WorldWideScience

Sample records for manufacture commercial application

  1. Nanomanufacturing Portfolio: Manufacturing Processes and Applications to Accelerate Commercial Use of Nanomaterials

    Energy Technology Data Exchange (ETDEWEB)

    Industrial Technologies Program

    2011-01-05

    This brochure describes the 31 R&D projects that AMO supports to accelerate the commercial manufacture and use of nanomaterials for enhanced energy efficiency. These cost-shared projects seek to exploit the unique properties of nanomaterials to improve the functionality of industrial processes and products.

  2. Application of commercial sensor manufacturing methods for NOx/NH3 mixed potential sensors for emissions control

    Energy Technology Data Exchange (ETDEWEB)

    Brosha, Eric L [Los Alamos National Laboratory; Mukundan, Rangachary [Los Alamos National Laboratory; Nelson, Mark A [Los Alamos National Laboratory; Sekhar, Praveen [Los Alamos National Laboratory; Williamson, Todd [Los Alamos National Laboratory; Garzon, Fernando H [Los Alamos National Laboratory

    2009-01-01

    The purpose of this research effort is to develop a low cost on-board Nitrogen Oxide (NO{sub x})/Ammonia (NH{sub 3}) sensor that can not only be used for emissions control but has the potential to improve efficiency through better monitoring of the combustion process and feedback control in both vehicle and stationary systems. Over the past decade, Los AJamos National Laboratory (LANL) has developed a unique class of electrochemical gas sensors for the detection of carbon monoxide, hydrocarbons, hydrogen and nitrogen oxides. These sensors are based on the mixed-potential phenomenon and are a modification of the existing automotive lambda (oxygen) sensor and have the potential to meet the stringent sensitivity, selectivity and stability requirements of an on-board emissions/engine control sensor system. The current state of the art LANL technology is based on the stabilization of the electrochemical interfaces and relies on an externally heated, hand-made, tape cast device. We are now poised to apply our patented sensing principles in a mass production sensor platform that is more suitable for real world engine-out testing such as on dynamometers for vehicle applications and for exhaust-out testing in heavy boilers/SCR systems in power plants. In this present work, our goal is to advance towards commercialization of this technology by packaging the unique LANL sensor design in a standard automotive sensor-type platform. This work is being performed with the help of a leading US technical ceramics firm, utilizing commercial manufacturing techniques. Initial tape cast platforms with screen printed metal oxide and Pt sensor electrodes have shown promising results but also clearly show the need for us to optimize the electrode and electrolyte compositions/morphologies and interfaces of these devices in order to demonstrate a sensitive, selective, and stable NO{sub x} sensor. Our previous methods and routes to preparing stable and reproducible mixed potential sensors

  3. Commercial applications

    International Nuclear Information System (INIS)

    Anon.

    1982-01-01

    The objective of this paper is to assess the near term (one-to-five-year) needs of domestic and foreign commercial suppliers of radiochemicals and radiopharmaceuticals for electromagnetically separated stable isotopes. Only isotopes purchased to make products for sale and profit are considered in this assessment. Radiopharmaceuticals produced from enriched stable isotopes supplied by the Calutron facility at ORNL are used in about 600,000 medical procedures each year in the United States. A temporary or permanent disruption of the supply of stable isotopes to the domestic radiopharmaceutical industry could curtail, if not eliminate, the use of such diagnostic procedures as the thallium heart scan, the gallium cancer scan, the gallium abscess scan, and the low-radiation-dose thyroid scan. The word could in the preceding sentence is underlined because an alternative source of enriched stable isotopes does exist in the USSR. Alternative starting materials could, in theory, eventually be developed for both the thallium and gallium scans. The development of a new technology for these purposes, however, would take at least five years and would be expensive. Hence, any disruption of the supply of enriched isotopes from ORNL and the resulting unavailability of critical nuclear medicine procedures would have a dramatic negative effect on the level of health care in the United States

  4. Commercial applications

    Science.gov (United States)

    The near term (one to five year) needs of domestic and foreign commercial suppliers of radiochemicals and radiopharmaceuticals for electromagnetically separated stable isotopes are assessed. Only isotopes purchased to make products for sale and profit are considered. Radiopharmaceuticals produced from enriched stable isotopes supplied by the Calutron facility at ORNL are used in about 600,000 medical procedures each year in the United States. A temporary or permanent disruption of the supply of stable isotopes to the domestic radiopharmaceutical industry could curtail, if not eliminate, the use of such diagnostic procedures as the thallium heart scan, the gallium cancer scan, the gallium abscess scan, and the low radiation dose thyroid scan. An alternative source of enriched stable isotopes exist in the USSR. Alternative starting materials could, in theory, eventually be developed for both the thallium and gallium scans. The development of a new technology for these purposes, however, would take at least five years and would be expensive. Hence, any disruption of the supply of enriched isotopes from ORNL and the resulting unavailability of critical nuclear medicine procedures would have a dramatic negative effect on the level of health care in the United States.

  5. Commercial applications for COIL

    Science.gov (United States)

    Solomon, Wayne C.; Carroll, David L.; King, D. M.; Fockler, L. A.; Stromberg, D. S.; Sexauer, M.; Milmoe, A.; Sentman, Lee H.

    2000-01-01

    The chemical oxygen-iodine laser (COIL) is a high power, fiber deliverable tool, which can be used for a number of different industrial applications. COIL is of particular interest because of its short fiber deliverable wavelength, high scaleable continuous wave power, and excellent material interaction properties. In past research the University of Illinois at Urbana-Champaign identified and decommissioning and decontamination (DD) of nuclear facilities as a primary focus for COIL technology. DD will be a major challenge in the coming decades. The use of a robotically driven fiber delivered cutting/ablation tool in contaminated areas promises to lower risks to workers for the DD mission. Further, the high cutting speed of COIL will significantly reduce the time required to cut contaminated equipment, reducing costs. The high power of COIL will permit the dismantling of thick stacks of piping and equipment as well as reactor vessels. COIL is very promising for the removal of material from contaminated surfaces, perhaps to depths thicker than an inch. Laser cutting and ablation minimizes dust and fumes, which reduces the required number of high efficiency particulate accumulator filters, thus reducing costly waste disposal. Other potential industrial applications for COIL are shipbuilding, automotive manufacturing, heavy machinery manufacturing, tasks requiring underwater cutting or welding, and there appear to be very promising applications for high powers lasers in the oil industry.

  6. Green Manufacturing Fundamentals and Applications

    CERN Document Server

    2013-01-01

    Green Manufacturing: Fundamentals and Applications introduces the basic definitions and issues surrounding green manufacturing at the process, machine and system (including supply chain) levels. It also shows, by way of several examples from different industry sectors, the potential for substantial improvement and the paths to achieve the improvement. Additionally, this book discusses regulatory and government motivations for green manufacturing and outlines the path for making manufacturing more green as well as making production more sustainable. This book also: • Discusses new engineering approaches for manufacturing and provides a path from traditional manufacturing to green manufacturing • Addresses regulatory and economic issues surrounding green manufacturing • Details new supply chains that need to be in place before going green • Includes state-of-the-art case studies in the areas of automotive, semiconductor and medical areas as well as in the supply chain and packaging areas Green Manufactu...

  7. Commercial Manure Applicators

    Data.gov (United States)

    Iowa State University GIS Support and Research Facility — This layer represents the office location for Commercial Manure Services (CMS). They transport, handle, store or apply manure for a fee. The company must be licensed...

  8. Commercial Implementation of Model-Based Manufacturing of Nanostructured Metals

    Energy Technology Data Exchange (ETDEWEB)

    Lowe, Terry C. [Los Alamos National Laboratory

    2012-07-24

    Computational modeling is an essential tool for commercial production of nanostructured metals. Strength is limited by imperfections at the high strength levels that are achievable in nanostructured metals. Processing to achieve homogeneity at the micro- and nano-scales is critical. Manufacturing of nanostructured metals is intrinsically a multi-scale problem. Manufacturing of nanostructured metal products requires computer control, monitoring and modeling. Large scale manufacturing of bulk nanostructured metals by Severe Plastic Deformation is a multi-scale problem. Computational modeling at all scales is essential. Multiple scales of modeling must be integrated to predict and control nanostructural, microstructural, macrostructural product characteristics and production processes.

  9. Quasi-film commercials. Analysis of selected car manufacturer campaigns

    OpenAIRE

    Barczyk-Sitkowska, Agnieszka

    2017-01-01

    When seeking original forms of expression, contemporary commercials often reach for the achievements of film making. That is reflected in references to the conventions of certain film genres, and the references to particular films. The goal of the article was to present selected examples of the relationships between commercials and film, which can be found in car manufacturer advertising campaigns (Toyota, BMW, and Mercedes-Benz). The analysis of the gathered study material enabled me to iden...

  10. Micro manufacturing techniques and applications

    CERN Document Server

    Du, Ruxu; Li, Zifu

    2013-01-01

    Micro/meso-scale manufacturing has been developed in research fields of machining, forming, materials and others, but its potential to industries are yet to be fully realized. The theme of the current volume was to build a bridge joining academic research and industrial needs in micro manufacturing. Among the 12 papers selected for publication are three keynote addresses onmicro and desktop factories for micro/meso-scale manufacturing applicationsand future visions, tissue cutting mechanics and applications for needlecore biopsy and guidance, and micro-texturing onto amorphous carbonmaterials

  11. Application of manufactured products

    Science.gov (United States)

    Sastri, Sankar; Duke, Michael B.

    1992-01-01

    A wide range of products can be manufactured from the following materials: (1) lunar regolith or basalt; (2) regolith or rock beneficiated to concentrate plagioclase or other minerals; (3) iron, extracted from lunar soil or rocks by various means; (4) naturally occurring or easily obtained materials that have cementitious properties; and (5) byproducts of the above materials. Among the products that can be produced from these materials are the following: beams; plates and sheets; transparent plates (windows); bricks and blocks; pipes and tubes; low-density materials (foams); fiber, wire, and cables; foils and reflective coatings; hermetic seals (coatings); and formed objects. In addition to oxygen, which can be obtained by several processes, either from unbeneficiated regolith or by reduction of concentrated ilmenite, these materials make the simplest requirements of the lunar resource extraction system. A thorough analysis of the impact of these simplest products on the economics of space operations is not possible at this point. Research is necessary both to define optimum techniques and adapt them to space and to determine the probable market for the products so that the priority of various processes can be assessed. Discussions of the following products are presented: aerobraking heat shields; pressurized habitats; lunar photovoltaic farms; and agricultural systems.

  12. International Assessment of Carbon Nanotube Manufacturing and Applications

    National Research Council Canada - National Science Library

    Eklund, Peter; Ajayan, Pulickel; Blackmon, Robert; Hart, A. J; Kong, Jing; Pradhan, Bhabendra; Rao, Apparao; Rinzler, Andrew

    2007-01-01

    This WTEC study focuses on the manufacturing and applications of carbon nanotubes "CNTs" to identify recent progress in understanding the commercial potential of CNTs as viewed by academic, industrial...

  13. Commercial and PET radioisotope manufacturing with a medical cyclotron

    International Nuclear Information System (INIS)

    Boothe, T.E.; McLeod, T.F.; Plitnikas, M.; Kinney, D.; Tavano, E.; Feijoo, Y.; Smith, P.; Szelecsenyi, F.

    1993-01-01

    Mount Sinai has extensive experience in producing radionuclides for commercial sales and for incorporation into radiopharmaceuticals, including PET. Currently, an attempt is being made to supply radiochemicals to radiopharmaceutical manufacturers outside the hospital, to prepare radiopharmaceuticals for in-house use, and to prepare PET radiopharmaceuticals, such as 2-[F-18] FDG, for outside sales. This use for both commercial and PET manufacturing is atypical for a hospital-based cyclotron. To accomplish PET radiopharmaceutical sales, the hospital operates a nuclear pharmacy. A review of operational details for the past several years shows a continuing dependence on commercial sales which is reflected in research and developmental aspects and in staffing. Developmental efforts have centered primarily on radionuclide production, target development, and radiochemical processing optimization. (orig.)

  14. Commercial and PET radioisotope manufacturing with a medical cyclotron

    Science.gov (United States)

    Boothe, T. E.; McLeod, T. F.; Plitnikas, M.; Kinney, D.; Tavano, E.; Feijoo, Y.; Smith, P.; Szelecsényi, F.

    1993-06-01

    Mount Sinai has extensive experience in producing radionuclides for commercial sales and for incorporation into radiopharmaceuticals, including PET. Currently, an attempt is being made to supply radiochemicals to radiopharmaceutical manufacturers outside the hospital, to prepare radiopharmaceuticals for in-house use, and to prepare PET radiopharmaceuticals, such as 2-[F-18] FDG, for outside sales. This use for both commercial and PET manufacturing is atypical for a hospital-based cyclotron. To accomplish PET radiopharmaceutical sales, the hospital operates a nuclear pharmacy. A review of operational details for the past several years shows a continuing dependence on commercial sales which is reflected in research and developmental aspects and in staffing. Developmental efforts have centered primarily on radionuclide production, target development, and radiochemical processing optimization.

  15. Characterization and manufacture of braided composites for large commercial aircraft structures

    Science.gov (United States)

    Fedro, Mark J.; Willden, Kurtis

    1992-01-01

    Braided composite materials, one of the advanced material forms which is under investigation in Boeing's ATCAS program, have been recognized as a potential cost-effective material form for fuselage structural elements. Consequently, there is a strong need for more knowledge in the design, manufacture, test, and analysis of textile structural composites. The overall objective of this work is to advance braided composite technology towards applications to a large commercial transport fuselage. This paper summarizes the mechanics of materials and manufacturing demonstration results which have been obtained in order to acquire an understanding of how braided composites can be applied to a commercial fuselage. Textile composites consisting of 1D, 2D triaxial, and 3D braid patterns with thermoplastic and two RTM resin systems were investigated. The structural performance of braided composites was evaluated through an extensive mechanical test program. Analytical methods were also developed and applied to predict the following: internal fiber architectures, stiffnesses, fiber stresses, failure mechanisms, notch effects, and the entire history of failure of the braided composites specimens. The applicability of braided composites to a commercial transport fuselage was further assessed through a manufacturing demonstration. Three foot fuselage circumferential hoop frames were manufactured to demonstrate the feasibility of consistently producing high quality braided/RTM composite primary structures. The manufacturing issues (tooling requirements, processing requirements, and process/quality control) addressed during the demonstration are summarized. The manufacturing demonstration in conjunction with the mechanical test results and developed analytical methods increased the confidence in the ATCAS approach to the design, manufacture, test, and analysis of braided composites.

  16. Optimising the design and operation of semi-continuous affinity chromatography for clinical and commercial manufacture.

    Science.gov (United States)

    Pollock, James; Bolton, Glen; Coffman, Jon; Ho, Sa V; Bracewell, Daniel G; Farid, Suzanne S

    2013-04-05

    This paper presents an integrated experimental and modelling approach to evaluate the potential of semi-continuous chromatography for the capture of monoclonal antibodies (mAb) in clinical and commercial manufacture. Small-scale single-column experimental breakthrough studies were used to derive design equations for the semi-continuous affinity chromatography system. Verification runs with the semi-continuous 3-column and 4-column periodic counter current (PCC) chromatography system indicated the robustness of the design approach. The product quality profiles and step yields (after wash step optimisation) achieved were comparable to the standard batch process. The experimentally-derived design equations were incorporated into a decisional tool comprising dynamic simulation, process economics and sizing optimisation. The decisional tool was used to evaluate the economic and operational feasibility of whole mAb bioprocesses employing PCC affinity capture chromatography versus standard batch chromatography across a product's lifecycle from clinical to commercial manufacture. The tool predicted that PCC capture chromatography would offer more significant savings in direct costs for early-stage clinical manufacture (proof-of-concept) (∼30%) than for late-stage clinical (∼10-15%) or commercial (∼5%) manufacture. The evaluation also highlighted the potential facility fit issues that could arise with a capture resin (MabSelect) that experiences losses in binding capacity when operated in continuous mode over lengthy commercial campaigns. Consequently, the analysis explored the scenario of adopting the PCC system for clinical manufacture and switching to the standard batch process following product launch. The tool determined the PCC system design required to operate at commercial scale without facility fit issues and with similar costs to the standard batch process whilst pursuing a process change application. A retrofitting analysis established that the direct cost

  17. Additive Manufacturing: Ensuring Quality for Spacecraft Applications

    Science.gov (United States)

    Swanson, Theodore; Stephenson, Timothy

    2014-01-01

    Reliable manufacturing requires that material properties and fabrication processes be well defined in order to insure that the manufactured parts meet specified requirements. While this issue is now relatively straightforward for traditional processes such as subtractive manufacturing and injection molding, this capability is still evolving for AM products. Hence, one of the principal challenges within AM is in qualifying and verifying source material properties and process control. This issue is particularly critical for applications in harsh environments and demanding applications, such as spacecraft.

  18. Commercial applications of perfluorocarbon tracer (PFT) technology

    International Nuclear Information System (INIS)

    Dietz, R.N.

    1991-06-01

    Tracer technology can be successfully applied to many leak-checking and monitoring evaluations of operating systems (e.g., building HVACs), manufacturing processes and products (e.g., air conditioners), and subsurface components and systems (e.g., underground storage tanks). Perfluorocarbon tracer (PFT) technology is the most sensitive of all tracer technologies because the ambient background levels of the five (5) routinely-used PFTs are in the range of parts per 10 15 parts of air (i.e., parts per quadrillion-ppq) and this technology's instrumentation can measure down to those levels. The effectiveness of this technology is achieved both in terms of cost (very little PFT need to be used) and detectability; for example, very small leaks can be rapidly detected. The PFT compounds, which are environmentally and biologically safe to use, are commercially available as are the sampling and analysis instrumentation. This presentation concerns (1) the steps being taken to commercialize this technology, (2) new applications of processes currently under study, and (3) applications in areas of use that will be particularly beneficial to the environment. 21 refs., 2 figs., 2 tabs

  19. Planning and Operation of Commercial Application Center

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Jun Yeon; Kim, Kye Ryung; Lee, Tae Joon; Lee, Jae Hyeong; Park, Je Won; Lee, Jae Sang

    2003-06-15

    The objectives of this R and D project are as follows : First, transferring developed technologies to outside companies and operating technology market to vitalize technology transactions, Second, developing commercial application projects to transfer technologies for commercial purposes and to solve interface problems in commercial applications, Third, enhancing commercial utilizations of developed accelerator and beam utilization technologies, Finally. preparing infra-structures for the development of over 30 venture- businesses based on achieved technologies through the Proton Engineering Frontier Project.

  20. Planning and Operation of Commercial Application Center

    International Nuclear Information System (INIS)

    Kim, Jun Yeon; Kim, Kye Ryung; Lee, Tae Joon; Lee, Jae Hyeong; Park, Je Won; Lee, Jae Sang

    2003-06-01

    The objectives of this R and D project are as follows : First, transferring developed technologies to outside companies and operating technology market to vitalize technology transactions, Second, developing commercial application projects to transfer technologies for commercial purposes and to solve interface problems in commercial applications, Third, enhancing commercial utilizations of developed accelerator and beam utilization technologies, Finally. preparing infra-structures for the development of over 30 venture- businesses based on achieved technologies through the Proton Engineering Frontier Project

  1. Commercial Electric Vehicle (EV) Development and Manufacturing Program

    Energy Technology Data Exchange (ETDEWEB)

    Leeve, Dion

    2014-06-30

    Navistar with the Department of Energy’s assistance undertook this effort to achieve the project objectives as listed in the next section. A wholly owned subsidiary of Navistar, Workhorse Sales Corporation was the original grant awardee and upon their discontinuation as a standalone business entity, Navistar assumed the role of principal investigator. The intent of the effort, as part of the American Recovery and Reinvestment Act (ARRA) was to produce zero emission vehicles that could meet the needs of the marketplace while reducing carbon emissions to zero. This effort was predicated upon the assumption that concurrent development activities in the lithium ion battery industry investigations would significantly increase their production volumes thus leading to substantial reductions in their manufacturing costs. As a result of this development effort much was learned about the overall system compatibility between the electric motor, battery pack, and charging capabilities. The original system was significantly revised and improved during the execution of this development effort. The overall approach that was chosen was to utilize a British zero emissions, class 2 truck that had been developed for their market, homologate it and modify it to meet the product requirements as specified in the grant details. All of these specific goals were achieved. During the course of marketing and selling the product valuable information was obtained as relates to customer expectations, price points, and product performance expectations, specifically those customer expectations about range requirements in urban delivery situations. While the grant requirements specified a range of 100 miles on a single charge, actual customer usage logs indicate a range of 40 miles or less is typical for their applications. The price point, primarily due to battery pack costs, was significantly higher than the mass market could bear. From Navistar’s and the overall industry’s perspective

  2. Lean Application to Manufacturing Ramp-Up

    DEFF Research Database (Denmark)

    Christensen, Irene; Rymaszewska, Anna

    2016-01-01

    . Abstracting from the extant literature, the authors considered the competitiveness of manufacturing companies from two principal perspectives: the leanness of the ramp-up process and the new-value creation of quality managers. While much of the literature fails to acknowledge that the roots of lean actually......This article provides a theoretical overview of the concepts of lean and manufacturing ramp-up in an attempt to conceptualize the strategic areas in which lean philosophy and principles can be applied for continuous improvements. The application of lean principles during the final stage of a new...... product development process, that is, the ramp-up process, is a critical, early enabler of lean manufacturing. The manufacturing strategy literature conceptualizes a state of “leanness in operations,” which can consolidate both the concepts of lean and manufacturing ramp-up, providing a dual perspective...

  3. Commercial application of rainfall simulation

    Science.gov (United States)

    Loch, Rob J.

    2010-05-01

    Landloch Pty Ltd is a commercial consulting firm, providing advice on a range of land management issues to the mining and construction industries in Australia. As part of the company's day-to-day operations, rainfall simulation is used to assess material erodibility and to investigate a range of site attributes. (Landloch does carry out research projects, though such are not its core business.) When treated as an everyday working tool, several aspects of rainfall simulation practice are distinctively modified. Firstly, the equipment used is regularly maintained, and regularly upgraded with a primary focus on ease, safety, and efficiency of use and on reliability of function. As well, trained and experienced technical support is considered essential. Landloch's chief technician has over 10 years experience in running rainfall simulators at locations across Australia and in Africa and the Pacific. Secondly, the specific experimental conditions established for each set of rainfall simulator runs are carefully considered to ensure that they accurately represent the field conditions to which the data will be subsequently applied. Considerations here include: • wetting and drying cycles to ensure material consolidation and/or cementation if appropriate; • careful attention to water quality if dealing with clay soils or with amendments such as gypsum; • strong focus on ensuring that the erosion processes considered are those of greatest importance to the field situation of concern; and • detailed description of both material and plot properties, to increase the potential for data to be applicable to a wider range of projects and investigations. Other important company procedures include: • For each project, the scientist or engineer responsible for analysing and reporting rainfall simulator data is present during the running of all field plots, as it is essential that they be aware of any specific conditions that may have developed when the plots were subjected

  4. Commercial applications of neutron scattering

    International Nuclear Information System (INIS)

    Hutchings, M.T.

    1993-01-01

    The fact that industry is now willing to pay the full commercial cost for certain neutron scattering experiments aimed at solving its urgent materials - related problems is a true testimony to the usefulness of neutrons as microscopic probes. This paper gives examples of such use of three techniques drawn mainly from our experience at AEA Technology Harwell Laboratory. These are diffraction to measure residual stress, small angle neutron scattering to examine hardening precipitates in ferritic steels brought about by irradiation, and reflectivity to study amorphous diamond layers deposited on silicon. In most cases it is the penetrative power of the neutron which proves to be its best asset for commercial industrial applicaitons. (author)

  5. Nanofiber Manufacture, Properties, and Applications

    International Nuclear Information System (INIS)

    Lin, T.; Lukas, D.; Bhat, G.S.

    2013-01-01

    Nano fibers have shown many unique characteristics and enormous application potential in widely diverse areas. While considerable research has been conducted on exploring the properties and applications of nano fibers over the decade, the technology development for large-scale production of nano fibers has been hampered, which slows down the wide applications of nano fibers in practice. This special issue focuses on the recent progress in emerging nano fiber production techniques, such as needle less electro spinning, and novel properties and applications of nano fibers. It also covers unusual methods to process natural materials into nano fibrous materials. The special issue consists of four review articles and eighteen research papers. One review paper presents an overview of the recent developments in needle less electro spinning and the influences of needle less spinnerets on electro spinning process, nano fiber quality and productivity. The review also points out the challenges remaining for further research in this area. Other three reviews separately summarize the preparation, characterization and applications of ZnO nano wires and the applications of carbon nano fibers for neural electrical/chemical interfaces and for cement reinforcement. The research articles report new results of needle less electro spinning techniques, and novel methods to make bi component nano fibers, porous nano fibers, nano fiber hydrogel and chitin nan ofibrils. As Guest Editors for this special issue, we are pleased to see the progress in the applications of nano fibers, especially for sound absorption and for protective clothing, as well as the antibacterial properties of titanate nano fibers. We hope this special issue will promote further development of large-scale economically feasible nano fiber-making technologies, and also contribute to the wide use of nano fibers. We also hope that the articles collected in this special issue are well-received by the reader.

  6. Commercial application of laser fusion

    International Nuclear Information System (INIS)

    Booth, L.A.

    1976-01-01

    The fundamentals of laser-induced fusion, some laser-fusion reactor concepts, and attendant means of utilizing the thermonuclear energy for commercial electric power generation are discussed. Theoretical fusion-pellet microexplosion energy release characteristics are described and the effects of pellet design options on pellet-microexplosion characteristics are discussed. The results of analyses to assess the engineering feasibility of reactor cavities for which protection of cavity components is provided either by suitable ablative materials or by diversion of plasmas by magnetic fields are presented. Two conceptual laser-fusion electric generating stations, based on different laser-fusion reactor concepts, are described

  7. A new application for food customization with additive manufacturing technologies

    Science.gov (United States)

    Serenó, L.; Vallicrosa, G.; Delgado, J.; Ciurana, J.

    2012-04-01

    Additive Manufacturing (AM) technologies have emerged as a freeform approach capable of producing almost any complete three dimensional (3D) objects from computer-aided design (CAD) data by successively adding material layer by layer. Despite the broad range of possibilities, commercial AM technologies remain complex and expensive, making them suitable only for niche applications. The developments of the Fab@Home system as an open AM technology discovered a new range of possibilities of processing different materials such as edible products. The main objective of this work is to analyze and optimize the manufacturing capacity of this system when producing 3D edible objects. A new heated syringe deposition tool was developed and several process parameters were optimized to adapt this technology to consumers' needs. The results revealed in this study show the potential of this system to produce customized edible objects without qualified personnel knowledge, therefore saving manufacturing costs compared to traditional technologies.

  8. Commercialization of new biotechnology: a systematic review of 16 commercial case studies in a novel manufacturing sector.

    Science.gov (United States)

    Paul, Matthew J; Thangaraj, Harry; Ma, Julian K-C

    2015-10-01

    The 1980s and 1990s saw a major expansion of biotechnology into new areas of science including genomics and recombinant technologies. This was coupled to the widespread emergence of academics into the commercial sector as they were encouraged to spin out companies or commercialize their intellectual property. There were many opportunities to raise investment, and extraordinary success stories were prominent across many areas of technology. The field of plant biotechnology for manufacturing recombinant pharmaceuticals (molecular pharming) emerged and was developed in this period. Like other biotechnologies, this was an exciting new development which offered some very obvious benefits and commercial advantages. In particularly, plant molecular pharming represented a highly novel and potentially disruptive manufacturing technology for recombinant proteins. Twenty-five years on, a series of interviews with senior members of sixteen of the most prominent companies involved in the field provides insight into the original drivers for commercialization, strategic thinking and planning behind key commercial decisions and an insider view into the major reasons for commercial success or failure. These observations and recurring themes identified across a number of commercial ventures remain relevant today, as new biotech companies continue to spin out of the world of academia. © 2015 Society for Experimental Biology, Association of Applied Biologists and John Wiley & Sons Ltd.

  9. Non-manufacturing applications of robotics

    International Nuclear Information System (INIS)

    Dauchez, P.

    2000-12-01

    This book presents the different non-manufacturing sectors of activity where robotics can have useful or necessary applications: underwater robotics, agriculture robotics, road work robotics, nuclear robotics, medical-surgery robotics, aids to disabled people, entertainment robotics. Service robotics has been voluntarily excluded because this developing sector is not mature yet. (J.S.)

  10. Commercial application of fault tree analysis

    International Nuclear Information System (INIS)

    Crosetti, P.A.; Bruce, R.A.

    1970-01-01

    The potential for general application of Fault Tree Analysis to commercial products appears attractive based not only on the successful extension from the aerospace safety technology to the nuclear reactor reliability and availability technology, but also because combinatorial hazards are common to commercial operations and therefore lend themselves readily to evaluation by Fault Tree Analysis. It appears reasonable to conclude that the technique has application within the commercial industrial community where the occurrence of a specified consequence or final event would be of sufficient concern to management to justify such a rigorous analysis as an aid to decision making. (U.S.)

  11. Wood energy-commercial applications

    Science.gov (United States)

    Kennel, R. P.

    1978-01-01

    Wood energy is being widely investigated in many areas of the country because of the many obvious benefits of wood fuel such as the low price per million Btus relative to coal, oil, and gas; the wide availability of noncommercial wood and the proven ability to harvest it; established technology which is reliable and free of pollution; renewable resources; better conservation for harvested land; and the potential for jobs creation. The Southeastern United States has a specific leadership role in wood energy based on its established forest products industry experience and the potential application of wood energy to other industries and institutions. Significant questions about the widespread usage of wood energy are being answered in demonstrations around the country as well as the Southeast in areas of wood storage and bulk handling; high capitalization costs for harvesting and combustion equipment; long term supply and demand contracts; and the economic feasibility of wood energy outside the forest products industry.

  12. Commercial Demonstration of the Manufactured Aggregate Processing Technology Utilizing Spray Dryer Ash

    Energy Technology Data Exchange (ETDEWEB)

    Milton Wu; Paul Yuran

    2006-12-31

    Universal Aggregates LLC (UA) was awarded a cost sharing Co-operative Agreement from the Department of Energy (DOE) through the Power Plant Improvement Initiative Program (PPII) to design, construct and operate a lightweight aggregate manufacturing plant at the Birchwood Power Facility in King George, Virginia in October 2001. The Agreement was signed in November 2002. The installation and start-up expenses for the Birchwood Aggregate Facility are $19.5 million. The DOE share is $7.2 million (37%) and the UA share is $12.3 million (63%). The original project team consists of UA, SynAggs, LLC, CONSOL Energy Inc. and P. J. Dick, Inc. Using 115,000 ton per year of spray dryer ash (SDA), a dry FGD by-product from the power station, UA will produce 167,000 tons of manufactured lightweight aggregate for use in production of concrete masonry units (CMU). Manufacturing aggregate from FGD by-products can provide an economical high-volume use and substantially expand market for FGD by-products. Most of the FGD by-products are currently disposed of in landfills. Construction of the Birchwood Aggregate Facility was completed in March 2004. Operation startup was begun in April 2004. Plant Integration was initiated in December 2004. Integration includes mixing, extrusion, curing, crushing and screening. Lightweight aggregates with proper size gradation and bulk density were produced from the manufacturing aggregate plant and loaded on a stockpile for shipment. The shipped aggregates were used in a commercial block plant for CMU production. However, most of the production was made at low capacity factors and for a relatively short time in 2005. Several areas were identified as important factors to improve plant capacity and availability. Equipment and process control modifications and curing vessel clean up were made to improve plant operation in the first half of 2006. About 3,000 tons of crushed aggregate was produced in August 2006. UA is continuing to work to improve plant

  13. Commercial applications of inertial confinement fusion

    International Nuclear Information System (INIS)

    Booth, L.A.; Frank, T.G.

    1977-05-01

    This report describes the fundamentals of inertial-confinement fusion, some laser-fusion reactor (LFR) concepts, and attendant means of utilizing the thermonuclear energy for commercial electric power generation. In addition, other commercial energy-related applications, such as the production of fissionable fuels, of synthetic hydrocarbon-based fuels, and of process heat for a variety of uses, as well as the environmental and safety aspects of fusion energy, are discussed. Finally, the requirements for commercialization of laser fusion technologies are described

  14. Additive manufacturing techniques and their biomedical applications

    Directory of Open Access Journals (Sweden)

    Yujing Liu

    2017-12-01

    Full Text Available Additive manufacturing (AM, also known as three-dimensional (3D printing, is gaining increasing attention in medical fields, especially in dental and implant areas. Because AM technologies have many advantages in comparison with traditional technologies, such as the ability to manufacture patient-specific complex components, high material utilization, support of tissue growth, and a unique customized service for individual patients, AM is considered to have a large potential market in medical fields. This brief review presents the recent progress of 3D-printed biomedical materials for bone applications, mainly for metallic materials, including multifunctional alloys with high strength and low Young’s modulus, shape memory alloys, and their 3D fabrication by AM technologies. It describes the potential of 3D printing techniques in precision medicine and community health.

  15. Fully Disposable Manufacturing Concepts for Clinical and Commercial Manufacturing and Ballroom Concepts.

    Science.gov (United States)

    Boedeker, Berthold; Goldstein, Adam; Mahajan, Ekta

    2017-11-04

    The availability and use of pre-sterilized disposables has greatly changed the methods used in biopharmaceuticals development and production, particularly from mammalian cell culture. Nowadays, almost all process steps from cell expansion, fermentation, cell removal, and purification to formulation and storage of drug substances can be carried out in disposables, although there are still limitations with single-use technologies, particularly in the areas of pretesting and quality control of disposables, bag and connections standardization and qualification, extractables and leachables (E/L) validation, and dependency on individual vendors. The current status of single-use technologies is summarized for all process unit operations using a standard mAb process as an example. In addition, current pros and cons of using disposables are addressed in a comparative way, including quality control and E/L validation.The continuing progress in developing single-use technologies has an important impact on manufacturing facilities, resulting in much faster, less expensive and simpler plant design, start-up, and operation, because cell culture process steps are no longer performed in hard-piped unit operations. This leads to simpler operations in a lab-like environment. Overall it enriches the current landscape of available facilities from standard hard-piped to hard-piped/disposables hybrid to completely single-use-based production plants using the current segregation and containment concept. At the top, disposables in combination with completely and functionally closed systems facilitate a new, revolutionary design of ballroom facilities without or with much less segregation, which enables us to perform good manufacturing practice manufacturing of different products simultaneously in unclassified but controlled areas.Finally, single-use processing in lab-like shell facilities is a big enabler of transferring and establishing production in emergent countries, and this is

  16. Pattern database applications from design to manufacturing

    Science.gov (United States)

    Zhuang, Linda; Zhu, Annie; Zhang, Yifan; Sweis, Jason; Lai, Ya-Chieh

    2017-03-01

    Pattern-based approaches are becoming more common and popular as the industry moves to advanced technology nodes. At the beginning of a new technology node, a library of process weak point patterns for physical and electrical verification are starting to build up and used to prevent known hotspots from re-occurring on new designs. Then the pattern set is expanded to create test keys for process development in order to verify the manufacturing capability and precheck new tape-out designs for any potential yield detractors. With the database growing, the adoption of pattern-based approaches has expanded from design flows to technology development and then needed for mass-production purposes. This paper will present the complete downstream working flows of a design pattern database(PDB). This pattern-based data analysis flow covers different applications across different functional teams from generating enhancement kits to improving design manufacturability, populating new testing design data based on previous-learning, generating analysis data to improve mass-production efficiency and manufacturing equipment in-line control to check machine status consistency across different fab sites.

  17. Material selection for design, manufacturing and application

    International Nuclear Information System (INIS)

    Zaid, A.I.O.

    2011-01-01

    Developing a new engineering material product or changing an existing one requires new design selecting material and choosing appropriate and economical manufacturing processes. These three main factors play a great role on the performance of the product in service. These items are independent and should not be performed in isolation from each other. With the great advancement of technology in the last decade and with the greater number of engineering materials which are now available, together with the increasing pressure to produce more economic and get reliable products an integrated approach which considers design, material selection and the appropriate manufacturing process makes it easier to achieve the optimum product that combines the functional requirements with the reliability at competitive cost. These diverse activities or items are interdependent; therefore should not be considered in isolation from each other, for example, it is not sufficient that design of the product should satisfy the technical, safety and legal requirements, it must also be possible to be manufactured economically and to be sold at a competitive price and easily disposed at the end of its working life cycle. In this paper, the interaction of these items together in order to arrive to the optimum solution for a particular application are given and discussed. (author)

  18. #%Applications of artificial intelligence in intelligent manufacturing: a review

    Institute of Scientific and Technical Information of China (English)

    #

    2017-01-01

    #%Based on research into the applications of artificial intelligence (AI) technology in the manufacturing industry in recent years, we analyze the rapid development of core technologies in the new era of 'Internet plus AI', which is triggering a great change in the models, means, and ecosystems of the manufacturing industry, as well as in the development of AI. We then propose new models, means, and forms of intelligent manufacturing, intelligent manufacturing system architecture, and intelligent man-ufacturing technology system, based on the integration of AI technology with information communications, manufacturing, and related product technology. Moreover, from the perspectives of intelligent manufacturing application technology, industry, and application demonstration, the current development in intelligent manufacturing is discussed. Finally, suggestions for the appli-cation of AI in intelligent manufacturing in China are presented.

  19. Manufacturing, regulatory and commercial challenges of biopharmaceuticals production: a Finnish perspective.

    Science.gov (United States)

    Närhi, Marko; Nordström, Katrina

    2005-04-01

    Biopharmaceuticals product development is a broad and multidisciplinary field. Science and technology are combined with new manufacturing, regulatory and commercial challenges. However, although there is ample literature on the molecular biology and biochemistry of products, the implementation of processes from test tube to commercial scale has not received similar attention. Consequently, the present study aims to highlight, from practical point of view, some of the key issues involved with manufacturing technologies of biopharmaceuticals at a commercial scale. Regulatory requirements and investments are also addressed based on the practical experiences of start-up and small companies. Finland is used as a case-example of such companies as this is a EU-member state with strong technological growth and rapidly increasing number of biotech companies.

  20. REVIEW OF WATER JET APPLICATIONS IN MANUFACTURING

    Directory of Open Access Journals (Sweden)

    Faruk MENDİ

    1999-02-01

    Full Text Available Usage of water jets in manufacturing processes, has been known for many decades. A wide range of engineering materials can be cut by water jets with satisfactory results. Enhanced reliability and efficiency of the technique, have yielded the technology greater interest for manufacturing applications. Water jets are used to cut soft materials such as wood, plastics, aluminium and copper. Abrasive water jets are used to cut very hard materials such as titanium, inconel, glass and ceramics. It is impossible to cut these materials with classical cutting technics. A water jet processing system utilises water pressure in the range of 100Mpa-400Mpa, for the different applications. In abrasive water jet milling and abrasive water jet cutting processes, the pressure of the jet is about 400Mpa. In water jet surface penning, the jet pressure is about 100Mpa. The process of abrasives mixing with the water stream is a complex phenomena. Erosion processes involved in cutting not yet fully understood. The lack of understanding the process call for other strategies in finding appropriate ways to obtain a precision depth in cutting operation. In this paper the principles of water jet systems had been explained. Results of experiments that made on cutting process and surface strengthening with water jet had been given.

  1. Hazardous drug residue on exterior vial surfaces: evaluation of a commercial manufacturing process.

    Science.gov (United States)

    Power, Luci A; Sessink, Paul J M; Gesy, Kathy; Charbonneau, Flay

    2014-04-01

    Hazardous drug residue on the exterior surface of drug vials poses a potential risk for exposure of health care workers involved in handling these products. The purpose of this article is to heighten the awareness of this serious issue and to evaluate a commercial manufacturing process for removing and containing hazardous drug (HD) residue on exterior vial surfaces. Additionally, findings from this study are interpreted, incorporated into the current body of evidence, and discussed by experts in this field. This study includes separate evaluations for the presence or absence of surface drug contamination on the vials of 3 HD products: 5-fluorouracil, cisplatin, and methotrexate. The drug products were packaged in vials using a patented prewashing/decontamination method, application of a polyvinylchloride (PVC) base, and use of clear glass vials. An additional step of encasing the vial in a shrink-wrapped sheath was used for 5-fluorouracil and cisplatin. Of all 5-fluorouracil (110 vials), methotrexate (60 vials), and cisplatin (60 vials) tested, only 2 had detectable amounts of surface residue. One 5-fluorouracil vial was found to have approximately 4 mg of 5-fluorouracil on the surface of the vial. The second contaminated vial was cisplatin, which was discovered to have 131 ng of platinum, equal to 200 ng of cisplatin or 0.2 μL of cisplatin solution, on the vial sheath. Using validated extraction and analytic methods, all but 2 of the 230 tested vials were found to be free of surface drug contamination. Pharmacy leaders need to take an active role in promoting the need for clean HD vials. Manufacturers should be required to provide their clients with data derived from externally validated analytic studies, reporting the level of HD contamination on the exterior of their vial products.

  2. The development of a commercial MOX fuel manufacturing capability in the U.K

    International Nuclear Information System (INIS)

    Macphee, D.S.; Young, M.P.

    1995-01-01

    BNFL is implementing a strategy to establish a commercial MOX manufacturing capability within the UK. The design and provision of the fabrication plants is incorporating the considerable experience within the Company of MOX technology, fuel fabrication and nuclear plant design. The first phase of the strategy is complete with the successful operation of the Demonstration Facility. The development programmes supporting the increased scale of operation for a commercial scale facility are substantially complete. Design and construction of a 120t HM/year plant is well advanced supported by a substantial in-house design and project management team. (author)

  3. ERAST: Scientific Applications and Technology Commercialization

    Science.gov (United States)

    Hunley, John D. (Compiler); Kellogg, Yvonne (Compiler)

    2000-01-01

    This is a conference publication for an event designed to inform potential contractors and appropriate personnel in various scientific disciplines that the ERAST (Environmental Research Aircraft and Sensor Technology) vehicles have reached a certain level of maturity and are available to perform a variety of missions ranging from data gathering to telecommunications. There are multiple applications of the technology and a great many potential commercial and governmental markets. As high altitude platforms, the ERAST vehicles can gather data at higher resolution than satellites and can do so continuously, whereas satellites pass over a particular area only once each orbit. Formal addresses are given by Rich Christiansen, (Director of Programs, NASA Aerospace Technology Ent.), Larry Roeder, (Senior Policy Advisor, U.S. Dept. of State), and Dr. Marianne McCarthy, (DFRC Education Dept.). The Commercialization Workshop is chaired by Dale Tietz (President, New Vista International) and the Science Workshop is chaired by Steve Wegener, (Deputy Manager of NASA ERAST, NASA Ames Research Center.

  4. Commercial grade item (CGI) dedication of MDR relays for nuclear safety related applications

    Science.gov (United States)

    Das, Ranjit K.; Julka, Anil; Modi, Govind

    1994-08-01

    MDR relays manufactured by Potter & Brumfield (P&B) have been used in various safety related applications in commercial nuclear power plants. These include emergency safety features (ESF) actuation systems, emergency core cooling systems (ECCS) actuation, and reactor protection systems. The MDR relays manufactured prior to May 1990 showed signs of generic failure due to corrosion and outgassing of coil varnish. P&B has made design changes to correct these problems in relays manufactured after May 1990. However, P&B does not manufacture the relays under any 10CFR50 Appendix B quality assurance (QA) program. They manufacture the relays under their commercial QA program and supply these as commercial grade items. This necessitates CGI Dedication of these relays for use in nuclear-safety-related applications. This paper presents a CGI dedication program that has been used to dedicate the MDR relays manufactured after been used to dedicate the MDR relays manufactured after May 1990. The program is in compliance with current Nuclear Regulatory Commission (NRC) and Electric Power Research Institute (EPRI) guidelines and applicable industry standards; it specifies the critical characteristics of the relays, provides the tests and analysis required to verify the critical characteristics, the acceptance criteria for the test results, performs source verification to quality P&B for its control of the critical characteristics, and provides documentation. The program provides reasonable assurance that the new MDR relays will perform their intended safety functions.

  5. A feasible approach to implement a commercial scale CANDU fuel manufacturing plant in Egypt

    International Nuclear Information System (INIS)

    El-Shehawy, I.; El-Sharaky, M.; Yasso, K.; Selim, I.; Graham, N.; Newington, D.

    1995-01-01

    Many planning scenarios have been examined to assess and evaluate the economic estimates for implementing a commercial scale CANDU fuel manufacturing plant in Egypt. The cost estimates indicated strong influence of the annual capital costs on total fuel manufacturing cost; this is particularly evident in a small initial plant where the proposed design output is only sufficient to supply reload fuel for a single CANDU-6 reactor. A modular approach is investigated as a possible way, to reduce the capital costs for a small initial fuel plant. In this approach the plant would do fuel assembly operations only and the remainder of a plant would be constructed and equipped in the stages when high production volumes can justify the capital expenses. Such approach seems economically feasible for implementing a small scale CANDU fuel manufacturing plant in developing countries such as Egypt and further improvement could be achieved over the years of operation. (author)

  6. Additive Layer Manufacturing for Launcher's Applications

    Science.gov (United States)

    Vilanova, J.; Romera, P.; Lasagni, F.; Zorrilla, A.; Perinan, A.

    2014-06-01

    In the next years the European space industry has the challenge of maintaining its competitiveness in launch vehicles (LV) production, due to the growth of competition worldwide. It has to assure its position developing new applied technologies. In this field the effort is focussed on the production of short series of customized products, like payloads, flight components or launcher parts. ALM (Additive Layer Manufacturing) could be a powerful tool that offers new competitiveness factors for this industry, comprising a set of emerging technologies that are becoming a competitor to forming, casting and machining as well as being utilised directly as a complementary alternative.Originally used for prototypes and models, now ALM becomes a very useful technology capable to fabricate functional parts for the space industrial sector. Its demands on rapid technologies are different to "earth" industries, and they aren't so easily satisfied because space is a field with different requirements depending on its application: launchers, reusable vehicles, satellites, probes, low gravity researches, manned spacecraft, or even moon and planetary exploration.This paper reports on the ALM potential applications, under ESA requirements, exploring the challenges and possibilities for its use in the launchers market, trying to answer two basic questions: the first one, whether ALM is a mature technology to be ready for its use as flight hardware; and the second one, if it can be used to reduce the product cycle, and consequently, the development, production and operational costs.

  7. Commercial-scale biotherapeutics manufacturing facility for plant-made pharmaceuticals.

    Science.gov (United States)

    Holtz, Barry R; Berquist, Brian R; Bennett, Lindsay D; Kommineni, Vally J M; Munigunti, Ranjith K; White, Earl L; Wilkerson, Don C; Wong, Kah-Yat I; Ly, Lan H; Marcel, Sylvain

    2015-10-01

    Rapid, large-scale manufacture of medical countermeasures can be uniquely met by the plant-made-pharmaceutical platform technology. As a participant in the Defense Advanced Research Projects Agency (DARPA) Blue Angel project, the Caliber Biotherapeutics facility was designed, constructed, commissioned and released a therapeutic target (H1N1 influenza subunit vaccine) in manufacturing facilities, with the capacity to process over 3500 kg of plant biomass per week in an automated multilevel growing environment using proprietary LED lighting. The facility can commission additional plant grow rooms that are already built to double this capacity. In addition to the commercial-scale manufacturing facility, a pilot production facility was designed based on the large-scale manufacturing specifications as a way to integrate product development and technology transfer. The primary research, development and manufacturing system employs vacuum-infiltrated Nicotiana benthamiana plants grown in a fully contained, hydroponic system for transient expression of recombinant proteins. This expression platform has been linked to a downstream process system, analytical characterization, and assessment of biological activity. This integrated approach has demonstrated rapid, high-quality production of therapeutic monoclonal antibody targets, including a panel of rituximab biosimilar/biobetter molecules and antiviral antibodies against influenza and dengue fever. © 2015 Society for Experimental Biology, Association of Applied Biologists and John Wiley & Sons Ltd.

  8. Case study of lean manufacturing application in a die casting manufacturing company

    Science.gov (United States)

    Ching, Ng Tan; Hoe, Clarence Chan Kok; Hong, Tang Sai; Ghobakhloo, Morteza; Pin, Chen Kah

    2015-05-01

    The case study of lean manufacturing aims to study the application of lean manufacturing in a die casting manufacturing company located in Pulau Penang, Malaysia. This case study describes mainly about the important concepts and applications of lean manufacturing which could gradually help the company in increasing the profit by studying and analyzing their current manufacturing process and company culture. Many approaches of lean manufacturing are studied in this project which includes: 5S housekeeping, Kaizen, and Takt Time. Besides, the lean tools mentioned, quality tool such as the House of Quality is being used as an analysis tool to continuously improve the product quality. In short, the existing lean culture in the company is studied and analyzed, with recommendations written at the end of this paper.

  9. 26 CFR 145.4061-1 - Application to manufacturers tax.

    Science.gov (United States)

    2010-04-01

    ... 26 Internal Revenue 17 2010-04-01 2010-04-01 false Application to manufacturers tax. 145.4061-1...) MISCELLANEOUS EXCISE TAXES (CONTINUED) TEMPORARY EXCISE TAX REGULATIONS UNDER THE HIGHWAY REVENUE ACT OF 1982 (PUB. L. 97-424) § 145.4061-1 Application to manufacturers tax. The provisions of § 145.4051-1(e) (1...

  10. COMMERCIAL DEMONSTRATION OF THE MANUFACTURED AGGREGATE PROCESSING TECHNOLOGY UTILIZING SPRAY DRYER ASH

    Energy Technology Data Exchange (ETDEWEB)

    Roy Scandrol

    2003-10-01

    Universal Aggregates, LLC proposes to design, construct and operate a lightweight aggregate manufacturing plant at the Birchwood Power Facility in King George, Virginia. The installation and start-up expenses for the Birchwood Aggregate Facility are $19.5 million. The DOE share is $7.2 million (37%) and the Universal Aggregates share is $12.3 (63%). The project team consists of CONSOL Energy Inc., P.J. Dick, Inc., SynAggs, LLC, and Universal Aggregates, LLC. The Birchwood Facility will transform 115,000 tons per year of spray dryer by-products that are currently being disposed of in an offsite landfill into 167,000 tons of a useful product, lightweight aggregates that can be used to manufacture lightweight aggregates that can be used to manufacture lightweight and medium weight masonry blocks. In addition to the environmental benefits, the Birchwood Facility will create nine (9) manufacturing jobs plus additional employment in the local trucking industry to deliver the aggregate to customers or reagents to the facility. A successful demonstration would lead to additional lightweight aggregate manufacturing facilities in the United States. There are currently twenty-one (21) spray dryer facilities operating in the United States that produce an adequate amount of spray dryer by-product to economically justify the installation of a lightweight aggregate manufacturing facility. Industry sources believe that as additional scrubbing is required, dry FGD technologies will be the technology of choice. Letters from potential lightweight aggregate customers indicate that there is a market for the product once the commercialization barriers are eliminated by this demonstration project.

  11. COMMERCIAL DEMONSTRATION OF THE MANUFACTURED AGGREGATE PROCESSING TECHNOLOGY UTILIZING SPRAY DRYER ASH

    Energy Technology Data Exchange (ETDEWEB)

    Roy Scandrol

    2003-04-01

    Universal Aggregates, LLC proposes to design, construct and operate a lightweight aggregate manufacturing plant at the Birchwood Power Facility in King George, Virginia. The installation and start-up expenses for the Birchwood Aggregate Facility are $19.5 million. The DOE share is $7.2 million (37%) and the Universal Aggregates share is $12.3 (63%). The project team consists of CONSOL Energy Inc., P.J. Dick, Inc., SynAggs, LLC, and Universal Aggregates, LLC. The Birchwood Facility will transform 115,000 tons per year of spray dryer by-products that are currently being disposed of in an offsite landfill into 167,000 tons of a useful product, lightweight aggregates that can be used to manufacture lightweight aggregates that can be used to manufacture lightweight and medium weight masonry blocks. In addition to the environmental benefits, the Birchwood Facility will create eight (8) manufacturing jobs plus additional employment in the local trucking industry to deliver the aggregate to customers or reagents to the facility. A successful demonstration would lead to additional lightweight aggregate manufacturing facilities in the United States. There are currently twenty-one (21) spray dryer facilities operating in the United States that produce an adequate amount of spray dryer by-product to economically justify the installation of a lightweight aggregate manufacturing facility. Industry sources believe that as additional scrubbing is required, dry flue gas desulfurization (FGD) technologies will be the technology of choice. Letters from potential lightweight aggregate customers indicate that there is a market for the product once the commercialization barriers are eliminated by this demonstration project.

  12. Commercial gasifier for IGCC applications study report

    Energy Technology Data Exchange (ETDEWEB)

    Notestein, J.E.

    1990-06-01

    This was a scoping-level study to identify and characterize the design features of fixed-bed gasifiers appearing most important for a gasifier that was to be (1) potentially commercially attractive, and (2) specifically intended for us in integrated coal gasification/combined-cycle (IGCC) applications. It also performed comparative analyses on the impact or value of these design features and on performance characteristics options of the whole IGCC system since cost, efficiency, environmental traits, and operability -- on a system basis -- are what is really important. The study also reviewed and evaluated existing gasifier designs, produced a conceptual-level gasifier design, and generated a moderately advanced system configuration that was utilized as the reference framework for the comparative analyses. In addition, technical issues and knowledge gaps were defined. 70 figs., 31 tabs.

  13. Potential commercial applications of centrifuge technology

    International Nuclear Information System (INIS)

    1985-08-01

    As part of an effort to prevent the loss of and maximize the use of unique developments of the centrifuge program, this document identifies and briefly describes unclassified technologies potentially available for transfer. In addition, this document presents a preliminary plan for action needed to carry out the transfer activity. Continuing efforts will provide additional descriptions of technologies which have applications that are not as apparent or as obvious as those presented here. Declassification of some of the program information, now classified as restricted data, would permit the descriptions of additional technologies which have significant commercial potential. The following are major areas of technology where transfer opportunities exist: biomedical; separation; motors and control systems; materials; vacuum; dynamics and balancing; and diagnostics and instrumentation

  14. Marine Carotenoids: Biological Functions and Commercial Applications

    Science.gov (United States)

    Vílchez, Carlos; Forján, Eduardo; Cuaresma, María; Bédmar, Francisco; Garbayo, Inés; Vega, José M.

    2011-01-01

    Carotenoids are the most common pigments in nature and are synthesized by all photosynthetic organisms and fungi. Carotenoids are considered key molecules for life. Light capture, photosynthesis photoprotection, excess light dissipation and quenching of singlet oxygen are among key biological functions of carotenoids relevant for life on earth. Biological properties of carotenoids allow for a wide range of commercial applications. Indeed, recent interest in the carotenoids has been mainly for their nutraceutical properties. A large number of scientific studies have confirmed the benefits of carotenoids to health and their use for this purpose is growing rapidly. In addition, carotenoids have traditionally been used in food and animal feed for their color properties. Carotenoids are also known to improve consumer perception of quality; an example is the addition of carotenoids to fish feed to impart color to farmed salmon. PMID:21556162

  15. Rubber - application of radiation to tire manufacture

    International Nuclear Information System (INIS)

    Hunt, J.D.; Alliger, G.

    1979-01-01

    Since the advent of commercial accelerators during the last several years capable of producing controllable electron beams of high energy, Firestone has devoted a considerable effort to the better understanding of the possible applications of such radiation to the production of tires or tire components. A number of chemical reactions can occur when elastomeric compounds are exposed to high energy waves, but crosslinking and degradation are the most important. The degree to which the crosslinking reaction predominates depends upon the nature of the rubber, compounding ingredients and the dosage. In general then, the effects achieved by the radiation of a rubber are quite similar to those resulting from heat. However, radiation cure or precure of compounds offers the advantage that the degree of crosslinking can be better controlled. Uniform crosslinking is possible since the high speed electrons penetrate uniformly throughout the sample. Curing with heat on the other hand may result in a greater degree of crosslinking on the surface of the sample than the center because of low heat conductivity. In general, radiation can be used to advantage to crosslink partially rubber tire components so that they retain better their shape and dimension during tire assembly and final cure or vulcanization. Added advantages of radiation precure include: a reduction of material usage, substitution of synthetic for natural rubber without loss in strength and the fact that partially crosslinked components will not thin out or become displaced during construction and vulcanization of the tire. (author)

  16. Process analytical technology in continuous manufacturing of a commercial pharmaceutical product.

    Science.gov (United States)

    Vargas, Jenny M; Nielsen, Sarah; Cárdenas, Vanessa; Gonzalez, Anthony; Aymat, Efrain Y; Almodovar, Elvin; Classe, Gustavo; Colón, Yleana; Sanchez, Eric; Romañach, Rodolfo J

    2018-03-01

    The implementation of process analytical technology and continuous manufacturing at an FDA approved commercial manufacturing site is described. In this direct compaction process the blends produced were monitored with a Near Infrared (NIR) spectroscopic calibration model developed with partial least squares (PLS) regression. The authors understand that this is the first study where the continuous manufacturing (CM) equipment was used as a gravimetric reference method for the calibration model. A principal component analysis (PCA) model was also developed to identify the powder blend, and determine whether it was similar to the calibration blends. An air diagnostic test was developed to assure that powder was present within the interface when the NIR spectra were obtained. The air diagnostic test as well the PCA and PLS calibration model were integrated into an industrial software platform that collects the real time NIR spectra and applies the calibration models. The PCA test successfully detected an equipment malfunction. Variographic analysis was also performed to estimate the sampling analytical errors that affect the results from the NIR spectroscopic method during commercial production. The system was used to monitor and control a 28 h continuous manufacturing run, where the average drug concentration determined by the NIR method was 101.17% of label claim with a standard deviation of 2.17%, based on 12,633 spectra collected. The average drug concentration for the tablets produced from these blends was 100.86% of label claim with a standard deviation of 0.4%, for 500 tablets analyzed by Fourier Transform Near Infrared (FT-NIR) transmission spectroscopy. The excellent agreement between the mean drug concentration values in the blends and tablets produced provides further evidence of the suitability of the validation strategy that was followed. Copyright © 2018 Elsevier B.V. All rights reserved.

  17. application of nanotechnology in the manufacturing sector

    African Journals Online (AJOL)

    eobe

    of nanomaterials by the modification of conventional production techniques techniques techniques. ... that goal through nano materials manufacture can only be found in the .... attainable by use of computer aided design programmes to specify ...

  18. Commercial Application of In-Space Assembly

    Science.gov (United States)

    Lymer, John; Hanson, Mark; Tadros, Al; Boccio, Joel; Hollenstein, Bruno; Emerick, Ken; Doughtery, Sean; Doggett, Bill; Dorsey, John T.; King, Bruce D.; hide

    2016-01-01

    In-Space assembly (ISA) expands the opportunities for cost effective emplacement of systems in space. Currently, spacecraft are launched into space and deploy into their operational configuration through a carefully choreographed sequence of operations. The deployment operation dictates the arrangement of the primary systems on the spacecraft, limiting the ability to take full advantage of launch vehicles volume and mass capability. ISA enables vastly different spacecraft architectures and emplacement scenarios to be achieved, including optimal launch configurations ranging from single launch and assembly to on-orbit aggregation of multiple launches at different orbital locations and times. The spacecraft can be visited at different orbital locations and times to effect expansion and maintenance of an operational capability. To date, the primary application of ISA has been in large programs funded by government organizations, such as the International Space Station. Recently, Space Systems Loral (SSL) led a study funded by the Defense Advanced Research Projects Agency (DARPA), called Dragonfly, to investigate the commercial applicability and economic advantages of ISA. In the study, it was shown that ISA enables SSL to double the capability of a commercial satellite system by taking advantage of alternate packaging approaches for the reflectors. The study included an ultra-light-weight robotic system, derived from Mars manipulator designs, to complete assembly of portions of the antenna system using a tool derived from DARPA orbital express and National Aeronautics and Space Administration (NASA) automated structural assembly experience. The mechanical connector that enables robotic ISA takes advantage of decades of development by NASA from the 1970's to 1980's during the Space Station Freedom program, the precursor to the ISS. The mechanical connector was originally designed for rapid astronaut assembly while also providing a high quality structural connection

  19. Feasibility of commercial space manufacturing, production of pharmaceuticals. Volume 2: Technical analysis

    Science.gov (United States)

    1978-01-01

    A technical analysis on the feasibility of commercial manufacturing of pharmaceuticals in space is presented. The method of obtaining pharmaceutical company involvement, laboratory results of the separation of serum proteins by the continuous flow electrophoresis process, the selection and study of candidate products, and their production requirements is described. The candidate products are antihemophilic factor, beta cells, erythropoietin, epidermal growth factor, alpha-1-antitrypsin and interferon. Production mass balances for antihemophelic factor, beta cells, and erythropoietin were compared for space versus ground operation. A conceptual description of a multiproduct processing system for space operation is discussed. Production requirements for epidermal growth factor of alpha-1-antitrypsin and interferon are presented.

  20. Integrated continuous bioprocessing: Economic, operational, and environmental feasibility for clinical and commercial antibody manufacture

    Science.gov (United States)

    Pollock, James; Coffman, Jon; Ho, Sa V.

    2017-01-01

    This paper presents a systems approach to evaluating the potential of integrated continuous bioprocessing for monoclonal antibody (mAb) manufacture across a product's lifecycle from preclinical to commercial manufacture. The economic, operational, and environmental feasibility of alternative continuous manufacturing strategies were evaluated holistically using a prototype UCL decisional tool that integrated process economics, discrete‐event simulation, environmental impact analysis, operational risk analysis, and multiattribute decision‐making. The case study focused on comparing whole bioprocesses that used either batch, continuous or a hybrid combination of batch and continuous technologies for cell culture, capture chromatography, and polishing chromatography steps. The cost of goods per gram (COG/g), E‐factor, and operational risk scores of each strategy were established across a matrix of scenarios with differing combinations of clinical development phase and company portfolio size. The tool outputs predict that the optimal strategy for early phase production and small/medium‐sized companies is the integrated continuous strategy (alternating tangential flow filtration (ATF) perfusion, continuous capture, continuous polishing). However, the top ranking strategy changes for commercial production and companies with large portfolios to the hybrid strategy with fed‐batch culture, continuous capture and batch polishing from a COG/g perspective. The multiattribute decision‐making analysis highlighted that if the operational feasibility was considered more important than the economic benefits, the hybrid strategy would be preferred for all company scales. Further considerations outside the scope of this work include the process development costs required to adopt continuous processing. © 2017 The Authors Biotechnology Progress published by Wiley Periodicals, Inc. on behalf of American Institute of Chemical Engineers Biotechnol. Prog., 33:854–866, 2017

  1. Integrated continuous bioprocessing: Economic, operational, and environmental feasibility for clinical and commercial antibody manufacture.

    Science.gov (United States)

    Pollock, James; Coffman, Jon; Ho, Sa V; Farid, Suzanne S

    2017-07-01

    This paper presents a systems approach to evaluating the potential of integrated continuous bioprocessing for monoclonal antibody (mAb) manufacture across a product's lifecycle from preclinical to commercial manufacture. The economic, operational, and environmental feasibility of alternative continuous manufacturing strategies were evaluated holistically using a prototype UCL decisional tool that integrated process economics, discrete-event simulation, environmental impact analysis, operational risk analysis, and multiattribute decision-making. The case study focused on comparing whole bioprocesses that used either batch, continuous or a hybrid combination of batch and continuous technologies for cell culture, capture chromatography, and polishing chromatography steps. The cost of goods per gram (COG/g), E-factor, and operational risk scores of each strategy were established across a matrix of scenarios with differing combinations of clinical development phase and company portfolio size. The tool outputs predict that the optimal strategy for early phase production and small/medium-sized companies is the integrated continuous strategy (alternating tangential flow filtration (ATF) perfusion, continuous capture, continuous polishing). However, the top ranking strategy changes for commercial production and companies with large portfolios to the hybrid strategy with fed-batch culture, continuous capture and batch polishing from a COG/g perspective. The multiattribute decision-making analysis highlighted that if the operational feasibility was considered more important than the economic benefits, the hybrid strategy would be preferred for all company scales. Further considerations outside the scope of this work include the process development costs required to adopt continuous processing. © 2017 The Authors Biotechnology Progress published by Wiley Periodicals, Inc. on behalf of American Institute of Chemical Engineers Biotechnol. Prog., 33:854-866, 2017. © 2017 The

  2. Pollution prevention applications in batch manufacturing operations

    Science.gov (United States)

    Sykes, Derek W.; O'Shaughnessy, James

    2004-02-01

    Older, "low-tech" batch manufacturing operations are often fertile grounds for gains resulting from pollution prevention techniques. This paper presents a pollution prevention technique utilized for wastewater discharge permit compliance purposes at a batch manufacturer of detergents, deodorants, and floor-care products. This manufacturer generated industrial wastewater as a result of equipment rinses required after each product batch changeover. After investing a significant amount of capital on end of pip-line wastewater treatment technology designed to address existing discharge limits, this manufacturer chose to investigate alternate, low-cost approaches to address anticipated new permit limits. Mass balances using spreadsheets and readily available formulation and production data were conducted on over 300 products to determine how each individual product contributed to the total wastewater pollutant load. These mass balances indicated that 22 products accounted for over 55% of the wastewater pollutant. Laboratory tests were conducted to determine whether these same products could accept their individual changeover rinse water as make-up water in formulations without sacrificing product quality. This changeover reuse technique was then implement at the plant scale for selected products. Significant reductions in wastewater volume (25%) and wastewater pollutant loading (85+%) were realized as a direct result of this approach.

  3. Evaluation of Large Grained UO{sub 2} Pellet's Manufacturability in a Commercial Plant and Development of its Technology

    Energy Technology Data Exchange (ETDEWEB)

    Lee, Seung Jae; Lee, J. N.; Lee, S. J. [Korea Nuclear Fuel Co. Ltd., Daejeon (Korea, Republic of)] (and others)

    2007-02-15

    To apply the various methods for grain growth of the fuel pellet to the commercial manufacturing process, which have been developed through the 'Advanced Fuel Pellet Development Program' in KAERI, it is necessary to conduct the performance test on the mass product line of UO{sub 2} pellets. For this purpose there are two main areas to be evaluated: The first area is the manufacturability of the lab-developed methods on large volume equipment (kg-batch) and commercial manufacturing scale. As a second part the material characteristics should satisfy the specification requirements for the UO{sub 2} pellet design. Above all, the applicability tests for the 'Seed' and 'Micro-doping' technology respectively were performed in the KNFC UO{sub 2} pellet commercial product line. These tests focused on the manufacturability on mass production and acceptable properties of the developed samples on demands of UO{sub 2} pellet design criteria. The tests showed very positive results. Judging from all the test results, the Al micro-doping method is likely to be the best way to enhance the grain size of UO{sub 2} pellet in the KNFC commercial product line without installation of any additional equipment. Through a series of additional reproducibility tests and process optimization, the micro-doping technology will be good applied for X-gen fuel pellet in the near future.

  4. Commercial Applications of X Ray Spectrometric Techniques

    International Nuclear Information System (INIS)

    Wegrzynek, D.

    2013-01-01

    In the 21st century, the X-ray fluorescence (XRF) technique is widely used in process control, industrial applications and for routine elemental analysis. The technique has a multielement capability capable of detecting elements with Z ≥ 10, with a few instruments capable of detecting also elements with Z ≥ 5. It is characterized by a non-destructive analysis process and relatively good detection limits, typically one part per million, for a wide range of elements. The first commercial XRF instruments were introduced to the market about 50 years ago. They were the wavelength dispersive X ray fluorescence (WDXRF) spectrometers utilizing Bragg’s law and reflection on crystal lattices for sequential elemental analysis of sample composition. The advances made in radiation detector technology, especially the introduction of semiconductor detectors, improvements in signal processing electronics, availability and exponential growth of personal computer market led to invention of energy dispersive X ray fluorescence (EDXRF) technique. The EDXRF is more cost effective as compared to WDXRF. It also allows for designing compact instruments. Such instruments can be easily tailored to the needs of different customers, integrated with industrial installations, and also miniaturized for the purpose of in-situ applications. The versatility of the technique has been confirmed in a spectacular way by using the XRF and X-ray spectrometric techniques, among few others, during the NASA and ESA missions in search for the evidence of life and presence of water on the surface of Mars. The XRF technique has achieved its strong position within the atomic spectroscopy group of analytical techniques not only due to its versatility but also due to relatively low running costs, as compared to the commonly used methods, e.g., atomic absorption spectrometry (AAS) or inductively coupled plasma atomic emission/mass spectrometry (ICP-AES/MS). Presently, the XRF technique together with X ray

  5. Commercial Applications of X Ray Spectrometric Techniques

    Energy Technology Data Exchange (ETDEWEB)

    Wegrzynek, D., E-mail: D.Wedgrznek@iaea.org [International Atomic Energy Agency, The IAEA Laboratories, Seibersdorf, Vienna (Austria)

    2013-07-15

    In the 21st century, the X-ray fluorescence (XRF) technique is widely used in process control, industrial applications and for routine elemental analysis. The technique has a multielement capability capable of detecting elements with Z {>=} 10, with a few instruments capable of detecting also elements with Z {>=} 5. It is characterized by a non-destructive analysis process and relatively good detection limits, typically one part per million, for a wide range of elements. The first commercial XRF instruments were introduced to the market about 50 years ago. They were the wavelength dispersive X ray fluorescence (WDXRF) spectrometers utilizing Bragg's law and reflection on crystal lattices for sequential elemental analysis of sample composition. The advances made in radiation detector technology, especially the introduction of semiconductor detectors, improvements in signal processing electronics, availability and exponential growth of personal computer market led to invention of energy dispersive X ray fluorescence (EDXRF) technique. The EDXRF is more cost effective as compared to WDXRF. It also allows for designing compact instruments. Such instruments can be easily tailored to the needs of different customers, integrated with industrial installations, and also miniaturized for the purpose of in-situ applications. The versatility of the technique has been confirmed in a spectacular way by using the XRF and X-ray spectrometric techniques, among few others, during the NASA and ESA missions in search for the evidence of life and presence of water on the surface of Mars. The XRF technique has achieved its strong position within the atomic spectroscopy group of analytical techniques not only due to its versatility but also due to relatively low running costs, as compared to the commonly used methods, e.g., atomic absorption spectrometry (AAS) or inductively coupled plasma atomic emission/mass spectrometry (ICP-AES/MS). Presently, the XRF technique together with X ray

  6. Development of Commercial Applications of a FAPY Alloy; TOPICAL

    International Nuclear Information System (INIS)

    Sikka, VK

    2001-01-01

    The Fe-16 at. (8.5 wt)% Al alloy, known as FAPY, has been identified as a superior material for heating element applications. However, while the 15-lb heats melted at the Oak Ridge National Laboratory (ORNL) could be processed into wire, the large heat melted at Hoskins Manufacturing Company (Hoskins) could not be processed under commercial processing conditions. The primary objective of the Cooperative Research and Development Agreement (CRADA) was to demonstrate that wire of the FAPY alloy could be produced under commercial conditions from air-induction-melted (AIM) heats. The specific aspects of this CRADA included: (1) Melting 15-lb heats by AIM or vacuum-induction melting (VIM) at ORNL. (2) Development of detailed processing steps including warm drawing and annealing temperature and time during cold-drawing steps. (3) Melting of 1400-lb heats at Hoskins by the Exo-Melt(trademark) process and their chemical analysis and microstructural characterization. (4) Development of tensile properties of sections of ingots from the large heats in the as-cast, hot-worked, and hot- and cold-worked conditions. (5) Microstructural characterization of cast and wrought structures and the fractured specimens. (6) Successful demonstration of processing of AIM heats at Hoskins to heating element wire. The aspects of this CRADA listed above have demonstrated that the FAPY alloy of the desired composition can be commercially produced by AIM by the use of the Exo-Melt(trademark) process. Furthermore, it also demonstrated that the wire processing steps developed for 15-lb heats at ORNL can be successfully applied to the production of wire from the large AIM heats

  7. Solid state laser applications in photovoltaics manufacturing

    Science.gov (United States)

    Dunsky, Corey; Colville, Finlay

    2008-02-01

    Photovoltaic energy conversion devices are on a rapidly accelerating growth path driven by increasing government and societal pressure to use renewable energy as part of an overall strategy to address global warming attributed to greenhouse gas emissions. Initially supported in several countries by generous tax subsidies, solar cell manufacturers are relentlessly pushing the performance/cost ratio of these devices in a quest to reach true cost parity with grid electricity. Clearly this eventual goal will result in further acceleration in the overall market growth. Silicon wafer based solar cells are currently the mainstay of solar end-user installations with a cost up to three times grid electricity. But next-generation technology in the form of thin-film devices promises streamlined, high-volume manufacturing and greatly reduced silicon consumption, resulting in dramatically lower per unit fabrication costs. Notwithstanding the modest conversion efficiency of thin-film devices compared to wafered silicon products (around 6-10% versus 15-20%), this cost reduction is driving existing and start-up solar manufacturers to switch to thin-film production. A key aspect of these devices is patterning large panels to create a monolithic array of series-interconnected cells to form a low current, high voltage module. This patterning is accomplished in three critical scribing processes called P1, P2, and P3. Lasers are the technology of choice for these processes, delivering the desired combination of high throughput and narrow, clean scribes. This paper examines these processes and discusses the optimization of industrial lasers to meet their specific needs.

  8. Design and application of reconfigurable manufacturing systems in agile mass customization manufacturing environment.

    CSIR Research Space (South Africa)

    Xing, B

    2007-05-01

    Full Text Available processes. Many manufacturing techniques are based on the principles of Flexible Manufacturing and Dedicated Manufacturing for mass production. Reconfigurable Manufacturing System, (RMS), is a manufacturing system that can provide for Agile Manufacturing...

  9. A commercial real-time manufacturing integration platform for the new control system on FTU

    International Nuclear Information System (INIS)

    Panella, M.; Bertocchi, A.; Bozzolan, V.; Buceti, G.; Centioli, C.; Imparato, A.; Mazza, G.; Torelli, C.; Vitale, V.

    1999-01-01

    In 1994 a working group was set up in Frascati to investigate how to build up a new control system for FTU (Frascati tokamak upgrade) considering the evolution in the information technology. Strong emphasis was placed on the use of standard solutions (be they de-facto or de-jure) and commercial platforms where-ever possible. This paper describes our operational experience with the new control system based on the commercial DEC BASEstar family of products. BASEstar is based on client/server computing technologies, providing an environment to collect, process, manage, distribute and integrate real time manufacturing data. UNIX, VMS, PC Win, OS-9 are integrated to handle hosts, PC, VME CPUs. A 4 GL programming language, CIMfast, has been used to handle via automatic procedures the tokamak discharge. X11 standard based mimics are available to display the plants status. A real flexibility of the whole system has been experience and the further use of the this system has been planned for the ITER DTP (divertor test platform). (orig.)

  10. NASA Technology Applications Team: Commercial applications of aerospace technology

    Science.gov (United States)

    1994-01-01

    The Research Triangle Institute (RTI) Team has maintained its focus on helping NASA establish partnerships with U.S. industry for dual use development and technology commercialization. Our emphasis has been on outcomes, such as licenses, industry partnerships and commercialization of technologies, that are important to NASA in its mission of contributing to the improved competitive position of U.S. industry. The RTI Team has been successful in the development of NASA/industry partnerships and commercialization of NASA technologies. RTI ongoing commitment to quality and customer responsiveness has driven our staff to continuously improve our technology transfer methodologies to meet NASA's requirements. For example, RTI has emphasized the following areas: (1) Methodology For Technology Assessment and Marketing: RTI has developed and implemented effective processes for assessing the commercial potential of NASA technologies. These processes resulted from an RTI study of best practices, hands-on experience, and extensive interaction with the NASA Field Centers to adapt to their specific needs. (2) Effective Marketing Strategies: RTI surveyed industry technology managers to determine effective marketing tools and strategies. The Technology Opportunity Announcement format and content were developed as a result of this industry input. For technologies with a dynamic visual impact, RTI has developed a stand-alone demonstration diskette that was successful in developing industry interest in licensing the technology. And (3) Responsiveness to NASA Requirements: RTI listened to our customer (NASA) and designed our processes to conform with the internal procedures and resources at each NASA Field Center and the direction provided by NASA's Agenda for Change. This report covers the activities of the Research Triangle Institute Technology Applications Team for the period 1 October 1993 through 31 December 1994.

  11. Applications of Fiber-Reinforced Polymers in Additive Manufacturing

    DEFF Research Database (Denmark)

    Hofstätter, Thomas; Pedersen, David Bue; Tosello, Guido

    2017-01-01

    Additive manufacturing technologies are these years entering the market of functional final parts. Initial research has been performed targeting the integration of fibers into additive manufactured plastic composites. Major advantages, among others, are for example increased tensile strength...... and Young's modulus. Key challenges in the field, as of now, are proper fiber placement, fiber seizing, an increased knowledge in the used materials and how they are applied into engineering solutions through proper control of the additive manufacturing process. The aim of this research is the improved...... understanding of fiber-reinforcement in additive manufacturing in terms of production and application. Vat polymerization and material extrusion techniques for composite additive manufacturing were investigated with respect of increasing adhesion between the matrix material and the fibers. Process optimization...

  12. Biomedical hydrogels biochemistry, manufacture and medical applications

    CERN Document Server

    Rimmer, Steve

    2011-01-01

    Hydrogels are very important for biomedical applications because they can be chemically manipulated to alter and control the hydrogel's interaction with cells and tissues. Their flexibility and high water content is similar to that of natural tissue, making them extremely suitable for biomaterials applications. Biomedical hydrogels explores the diverse range and use of hydrogels, focusing on processing methods and novel applications in the field of implants and prostheses. Part one of this book concentrates on the processing of hydrogels, covering hydrogel swelling behaviour, superabsorbent cellulose-based hydrogels and regulation of novel hydrogel products, as well as chapters focusing on the structure and properties of hydrogels and different fabrication technologies. Part two covers existing and novel applications of hydrogels, including chapters on spinal disc and cartilage replacement implants, hydrogels for ophthalmic prostheses and hydrogels for wound healing applications. The role of hydrogels in imag...

  13. Coke gasification costs, economics, and commercial applications

    International Nuclear Information System (INIS)

    Jahnke, F.C.; Falsetti, J.S.; Wilson, R.F.

    1996-01-01

    The disposition of petroleum coke remains a problem for modern high conversion refineries. Market uncertainty and the price for coke can prevent the implementation of otherwise attractive projects. The commercially proven Texaco Gasification Process remains an excellent option for clean, cost effective coke disposition as demonstrated by the new coke gasification units coming on-line and under design. Previous papers, have discussed the coke market and general economics of coke gasification. This paper updates the current market situation and economics, and provide more details on cost and performance based on recent studies for commercial plants

  14. Study, design and manufacture eddy current probes for industry applications

    International Nuclear Information System (INIS)

    Nguyen Phuc; Nguyen Van Thuy; Vuong Binh Duong; Do Minh Duc; Trinh Dinh Truong; Tran Trong Duc; Do Tung Khanh; Dang Quang Trung

    2016-01-01

    This study is based on the studying, designing and manufacturing of eddy current probes for industry applications. The main tasks of this study include: i) Describes the overview and classification of eddy current probes (which can be classified into three categories based on the mode of operation: absolute eddy current probe, differential eddy current probe and reflect eddy current probe); ii) Describes the three methods of probe designing and manufacturing (including experimental, analytical and numerical designs); iii) Describes the designing and manufacturing of eddy current probes for industry applications, which based on experimental and analytical methods. Based on this study, we have successfully manufactured some current probes (including absolute eddy current probe, differential eddy current probe and reflect eddy current probe) for surface and tube inspections. (author)

  15. APPLICATION OF ADDITIVELY MANUFACTURED POLYMER COMPOSITE PROTOTYPES IN FOUNDRY

    Directory of Open Access Journals (Sweden)

    Wiesław Kuczko

    2015-05-01

    Full Text Available The paper presents a method, developed by the authors, for manufacturing polymer composites with the matrix manufactured in a layered manner (via 3D printing – Fused Deposition Modeling out of a thermoplastic material. As an example of practical application of this method, functional prototypes are presented, which were used as elements of foundry tooling – patterns for sand molding. In case of manufacturing prototype castings or short series of products, foundries usually cooperate with modeling studios, which produce patterns by conventional, subtractive manufacturing technologies. If patterns have complex shapes, this results in high manufacturing costs and significantly longer time of tooling preparation. The method proposed by the authors allows manufacturing functional prototypes in a short time thanks to utilizing capabilities of additive manufacturing (3D printing technology. Thanks to using two types of materials simultaneously (ABS combined with chemically hardened resins, the produced prototypes are capable of carrying increased loads. Moreover, the method developed by the authors is characterized by manufacturing costs lower than in the basic technology of Fused Deposition Modeling. During the presented studies, the pattern was produced as a polymer composite and it was used to prepare a mold and a set of metal castings.

  16. Manufacturing and application of micro computer for control

    International Nuclear Information System (INIS)

    Park, Seung Man; Heo, Gyeong; Yun, Jun Young

    1990-05-01

    This book deals with machine code and assembly program for micro computer. It composed of 20 chapters, which are micro computer system, practice of a storage cell, manufacturing 1 of micro computer, manufacturing 2 of micro computer, manufacturing of micro computer AID-80A, making of machine language, interface like Z80-PIO and 8255A(PPI), counter and timer interface, exercise of basic command, arithmetic operation, arrangement operation, an indicator control, music playing, detection of input of PIO. control of LED of PIO, PIO mode, CTC control by micro computer, SIO control by micro computer and application by micro computer.

  17. Applications of Metal Additive Manufacturing in Veterinary Orthopedic Surgery

    Science.gov (United States)

    Harrysson, Ola L. A.; Marcellin-Little, Denis J.; Horn, Timothy J.

    2015-03-01

    Veterinary medicine has undergone a rapid increase in specialization over the last three decades. Veterinarians now routinely perform joint replacement, neurosurgery, limb-sparing surgery, interventional radiology, radiation therapy, and other complex medical procedures. Many procedures involve advanced imaging and surgical planning. Evidence-based medicine has also become part of the modus operandi of veterinary clinicians. Modeling and additive manufacturing can provide individualized or customized therapeutic solutions to support the management of companion animals with complex medical problems. The use of metal additive manufacturing is increasing in veterinary orthopedic surgery. This review describes and discusses current and potential applications of metal additive manufacturing in veterinary orthopedic surgery.

  18. Advanced LWR technology for commercial application

    International Nuclear Information System (INIS)

    Redding, J.R.

    1993-01-01

    Advanced Light Water Reactors (ALWRs) are now being deployed and commercialized around the world. In Japan, the Tokyo Electric Power Company (TEPCO) is building the world's first ALWRs, two 1300 MWe Advanced BWRs (ABWRs). In the United States, the Department of Energy, utilities and suppliers are undertaking a cooperative program called First of a Kind Engineering (FOAKE). The purpose of FOAKE is to perform the detailed engineering of ALWRs to that they will be commercially available to U.S. utilities in the mid-1990s. The U.S. industry is in the second year of its strategic plan to have an ALWR in commercial operation by the year 2000. Elsewhere, the Taiwan Power Company has issued a Request for Proposal for two ALWRs so be built at its Lungmen site, with commercial operation of the first unit to be in the year 2000. Korea is formulating plans for an ALWR and other countries, such as Indonesia and Mexico, are looking into the feasibility of building ALWRs

  19. Enabling laser applications in microelectronics manufacturing

    Science.gov (United States)

    Delmdahl, Ralph; Brune, Jan; Fechner, Burkhard; Senczuk, Rolf

    2016-02-01

    In this experimental study, we report on high-pulse-energy excimer laser drilling into high-performance build-up films which are pivotal in microelectronics manufacturing. Build-up materials ABF-GX13 from Ajinomoto as well as ZS-100 from Zeon Corporation are evaluated with respect to their viability for economic excimer laser-based micro-via formation. Excimer laser mask imaging projection at laser wavelengths of 193, 248 and 308 nm is employed to generate matrices of smaller micro-vias with different diameters and via pitches. High drilling quality is achievable for all excimer laser wavelengths with the fastest ablation rates measured in the case of 248 and 308 nm wavelengths. The presence of glass fillers in build-up films as in the ABF-GX13 material poses some limitations to the minimum achievable via diameter. However, surprisingly good drilling results are obtainable as long as the filler dimensions are well below the diameter of the micro-vias. Sidewall angles of vias are controllable by adjusting the laser energy density and pulse number. In this work, the structuring capabilities of excimer lasers in build-up films as to taper angle variations, attainable via diameters, edge-stop behavior and ablation rates will be elucidated.

  20. Commercial glass beads as TLDs in radiotherapy produced by different manufacturers

    Science.gov (United States)

    Jafari, S. M.; Bates, N. M.; Jupp, T.; Abdul Sani, S. F.; Nisbet, A.; Bradley, D. A.

    2017-08-01

    While commercial jewellery glass beads offer the basis of novel radiotherapy TL dosimetry (Jafari et al. 2014a,b,c, 2015a,b), detailed study of TL variation is required for the products from various manufacturers. Investigation is made for glass beads from four manufacturers from four countries: China (Rocaille), Japan (Mill Hill), Indonesia (TOHO™) and Czech Republic (Czech). Sample composition was determined using an energy-dispersive X-ray unit coupled to a scanning electron microscope. Values of mass attenuation coefficient, μ/ρ, as a function of photon energy were then calculated for photons of energy 1 keV to 10 MeV, using the National Institute of Standards and Technology XCOM program. Radiation and energy response were determined using X-rays generated at accelerating potentials from 80 kVp to 6 MV (TPR20/10=0.670). All bead types showed TL to be linear with dose (R2>0.999). Glow curve dosimetric peaks reached a maximum value at 300 °C for the Toho and 290 °C for the Czech and Mill Hill products but was between 200-250 °C for the Rocaille product. Radiation sensitivity following mass normalisation varied within an order of magnitude; Toho samples showed the greatest and Rocaille the least sensitivity. For the Toho, Czech, Rocaille and Mill Hill samples the energy responses at 80 kVp were 5.0, 4.0, 3.6 and 3.3 times that obtained at 6 MV. All four glass bead types offer potential use as TL dosimeters over doses commonly applied in radiotherapy. Energy response variation was <1% at 6 MV but significant variation was found for photon beam energies covering the kV range; careful characterisation is required if use at this range is intended.

  1. Additive manufacturing: state-of-the-art and application framework

    Directory of Open Access Journals (Sweden)

    Vinícius Picanço Rodrigues

    2017-09-01

    Full Text Available Additive manufacturing encompasses a class of production processes with increasing applications in different areas and supply chains. Due to its flexibility for production in small batches and the versatility of materials and geometries, this technology is recognized as being capable of revolutionizing the production processes as well as changing production strategies that are currently employed. However, there are different technologies under the generic label of additive manufacturing, materials and application areas with different requirements. Given the growing importance of additive manufacturing as a production process, and also considering the need to have a better insight into the potential applications for driving research and development efforts, this article presents a proposal of organization for additive manufacturing applications in seven areas. Additionally, the article provides a panorama of the current development stage of this technology, with a review of its major technological variants. The results presented aim to serve as a basis to support driving initiatives in additive manufacturing in companies, development agencies and research institutions.

  2. Current use and potential of additive manufacturing for optical applications

    Science.gov (United States)

    Brunelle, Matthew; Ferralli, Ian; Whitsitt, Rebecca; Medicus, Kate

    2017-10-01

    Additive manufacturing, or 3D printing, has become widely used in recent years for the creation of both prototype and end-use parts. Because the parts are created in a layer-by-layer manner, the flexibility of additive manufacturing is unparalleled and has opened the design space to enable features like undercuts and internal channels which cannot exist on traditional, subtractively manufactured parts. This flexibility can also be leveraged for optical applications. This paper outlines some of the current uses of 3D printing in the optical manufacturing process at Optimax. Several materials and additive technologies are utilized, including polymer printing through fused deposition modeling, which creates parts by depositing a softened thermoplastic filament in a layerwise fashion. Stereolithography, which uses light to cure layers of a photopolymer resin, will also be discussed. These technologies are used to manufacture functional prototypes, fixtures, sealed housings, and other components. Additionally, metal printing through selective laser melting, which uses a laser to melt metal powder layers into a dense solid, will be discussed due to the potential to manufacture thermally stable opticalmechanical assembly frameworks and functional optics. Examples of several additively manufactured optical components will be shown.

  3. Machine learning in manufacturing: advantages, challenges, and applications

    Directory of Open Access Journals (Sweden)

    Thorsten Wuest

    2016-01-01

    Full Text Available The nature of manufacturing systems faces ever more complex, dynamic and at times even chaotic behaviors. In order to being able to satisfy the demand for high-quality products in an efficient manner, it is essential to utilize all means available. One area, which saw fast pace developments in terms of not only promising results but also usability, is machine learning. Promising an answer to many of the old and new challenges of manufacturing, machine learning is widely discussed by researchers and practitioners alike. However, the field is very broad and even confusing which presents a challenge and a barrier hindering wide application. Here, this paper contributes in presenting an overview of available machine learning techniques and structuring this rather complicated area. A special focus is laid on the potential benefit, and examples of successful applications in a manufacturing environment.

  4. Additive manufacturing: state-of-the-art and application framework

    DEFF Research Database (Denmark)

    Rodrigues, Vinicius Picanco; de Senzi Zancul, Eduardo; Gonçalves Mançanares, Cauê

    2017-01-01

    Additive manufacturing encompasses a class of production processes with increasing applications indifferent areas and supply chains. Due to its flexibility for production in small batches and the versatilityof materials and geometries, this technology is recognized as being capable...... of revolutionizing theproduction processes as well as changing production strategies that are currently employed. However,there are different technologies under the generic label of additive manufacturing, materials and applicationareas with different requirements. Given the growing importance of additive...... manufacturingas a production process, and also considering the need to have a better insight into the potential applicationsfor driving research and development efforts, this article presents a proposal of organizationfor additive manufacturing applications in seven areas. Additionally, the article provides...

  5. Application of Contact Mode AFM to Manufacturing Processes

    Science.gov (United States)

    Giordano, Michael A.; Schmid, Steven R.

    A review of the application of contact mode atomic force microscopy (AFM) to manufacturing processes is presented. A brief introduction to common experimental techniques including hardness, scratch, and wear testing is presented, with a discussion of challenges in the extension of manufacturing scale investigations to the AFM. Differences between the macro- and nanoscales tests are discussed, including indentation size effects and their importance in the simulation of processes such as grinding. The basics of lubrication theory are presented and friction force microscopy is introduced as a method of investigating metal forming lubrication on the nano- and microscales that directly simulates tooling/workpiece asperity interactions. These concepts are followed by a discussion of their application to macroscale industrial manufacturing processes and direct correlations are made.

  6. 75 FR 69464 - Manufacturer of Controlled Substances; Notice of Application

    Science.gov (United States)

    2010-11-12

    ... DEPARTMENT OF JUSTICE Drug Enforcement Administration Manufacturer of Controlled Substances; Notice of Application Pursuant to Sec. 1301.33(a), Title 21 of the Code of Federal Regulations (CFR), this is notice that on July 16, 2009, Cerilliant Corporation, 811 Paloma Drive, Suite A, Round Rock...

  7. 77 FR 2321 - Manufacturer of Controlled Substances; Notice of Application

    Science.gov (United States)

    2012-01-17

    ... DEPARTMENT OF JUSTICE Drug Enforcement Administration Manufacturer of Controlled Substances; Notice of Application Pursuant to Sec. 1301.33(a), Title 21 of the Code of Federal Regulations (CFR), this is notice that on June 28, 2011, Cerilliant Corporation, 811 Paloma Drive, Suite A, Round Rock...

  8. 76 FR 36577 - Manufacturer of Controlled Substances; Notice of Application

    Science.gov (United States)

    2011-06-22

    ... DEPARTMENT OF JUSTICE Drug Enforcement Administration Manufacturer of Controlled Substances; Notice of Application Pursuant to Sec. 1301.33(a), Title 21 of the Code of Federal Regulations (CFR), this is notice that on May 4, 2011, Boehringer Ingelheim Chemicals Inc., 2820 N. Normandy Drive...

  9. 75 FR 32506 - Manufacturer of Controlled Substances; Notice of Application

    Science.gov (United States)

    2010-06-08

    ... DEPARTMENT OF JUSTICE Drug Enforcement Administration Manufacturer of Controlled Substances; Notice of Application Pursuant to Sec. 1301.33(a) of Title 21 of the Code of Federal Regulations (CFR), this is notice that on April 12, 2010, Boehringer Ingelheim Chemicals Inc., 2820 N. Normandy Drive...

  10. Composites Materials and Manufacturing Technologies for Space Applications

    Science.gov (United States)

    Vickers, J. H.; Tate, L. C.; Gaddis, S. W.; Neal, R. E.

    2016-01-01

    Composite materials offer significant advantages in space applications. Weight reduction is imperative for deep space systems. However, the pathway to deployment of composites alternatives is problematic. Improvements in the materials and processes are needed, and extensive testing is required to validate the performance, qualify the materials and processes, and certify components. Addressing these challenges could lead to the confident adoption of composites in space applications and provide spin-off technical capabilities for the aerospace and other industries. To address the issues associated with composites applications in space systems, NASA sponsored a Technical Interchange Meeting (TIM) entitled, "Composites Materials and Manufacturing Technologies for Space Applications," the proceedings of which are summarized in this Conference Publication. The NASA Space Technology Mission Directorate and the Game Changing Program chartered the meeting. The meeting was hosted by the National Center for Advanced Manufacturing (NCAM)-a public/private partnership between NASA, the State of Louisiana, Louisiana State University, industry, and academia, in association with the American Composites Manufacturers Association. The Louisiana Center for Manufacturing Sciences served as the coordinator for the TIM.

  11. Optical intersatellite links - Application to commercial satellite communications

    Science.gov (United States)

    Paul, D.; Faris, F.; Garlow, R.; Inukai, T.; Pontano, B.; Razdan, R.; Ganz, Aura; Caudill, L.

    1992-01-01

    Application of optical intersatellite links for commercial satellite communications services is addressed in this paper. The feasibility of commercialization centers around basic issues such as the need and derived benefits, implementation complexity and overall cost. In this paper, commercialization of optical ISLs is assessed in terms of the services provided, systems requirements and feasibility of appropriate technology. Both long- and short-range ISLs for GEO-GEO, GEO-LEO and LEO applications are considered. Impact of systems requirements on the payload design and use of advanced technology in reducing its mass, power, and volume requirements are discussed.

  12. Diffractive optics for industrial and commercial applications

    Energy Technology Data Exchange (ETDEWEB)

    Turunen, J. [Joensuu Univ. (Finland); Wyrowski, F. [eds.] [Jena Univ. (Germany)

    1997-12-31

    The following topics were dealt with: diffractive optics, diffraction gratings, optical system design with diffractive optics, continuous-relief diffractive lenses and microlens arrays, diffractive bifocal intraocular lenses, diffractive laser resonators, diffractive optics for semiconductor lasers, diffractive elements for optical image processing, photorefractive crystals in optical measurement systems, subwavelenth-structured elements, security applications, diffractive optics for solar cells, holographic microlithography. 999 refs.

  13. Using microwave Doppler radar in automated manufacturing applications

    Science.gov (United States)

    Smith, Gregory C.

    Since the beginning of the Industrial Revolution, manufacturers worldwide have used automation to improve productivity, gain market share, and meet growing or changing consumer demand for manufactured products. To stimulate further industrial productivity, manufacturers need more advanced automation technologies: "smart" part handling systems, automated assembly machines, CNC machine tools, and industrial robots that use new sensor technologies, advanced control systems, and intelligent decision-making algorithms to "see," "hear," "feel," and "think" at the levels needed to handle complex manufacturing tasks without human intervention. The investigator's dissertation offers three methods that could help make "smart" CNC machine tools and industrial robots possible: (1) A method for detecting acoustic emission using a microwave Doppler radar detector, (2) A method for detecting tool wear on a CNC lathe using a Doppler radar detector, and (3) An online non-contact method for detecting industrial robot position errors using a microwave Doppler radar motion detector. The dissertation studies indicate that microwave Doppler radar could be quite useful in automated manufacturing applications. In particular, the methods developed may help solve two difficult problems that hinder further progress in automating manufacturing processes: (1) Automating metal-cutting operations on CNC machine tools by providing a reliable non-contact method for detecting tool wear, and (2) Fully automating robotic manufacturing tasks by providing a reliable low-cost non-contact method for detecting on-line position errors. In addition, the studies offer a general non-contact method for detecting acoustic emission that may be useful in many other manufacturing and non-manufacturing areas, as well (e.g., monitoring and nondestructively testing structures, materials, manufacturing processes, and devices). By advancing the state of the art in manufacturing automation, the studies may help

  14. Comparative Analysis of the Factors Necessitating Commercial Banks and Manufacturing Firms’ Involvement in Corporate Social Responsibility in Nigeria

    Directory of Open Access Journals (Sweden)

    Abiola Idowu

    2016-11-01

    Full Text Available This research investigates the factors necessitating commercial banks and manufacturing firms’ involvement in Corporate Social Responsibility (CSR in Nigeria comparatively. The research took place in Lagos State in South-west geo-political zone in Nigeria. The survey research design was used in this research. Moreover, the purposive sampling was used in selecting five commercial banks and five manufacturing firms. Primary data were gathered with the aid of questionnaire from 216 respondents out of 250 selected respondents from bank and 205 respondents out of 250 selected respondents from manufacturing firms. Fifty copies of the questionnaires were distributed to each company. All respondents selected were involved in CSR activities of their companies. Factors necessitating companies’ involvement in CSR were examined with Analysis of Variance. The research reveals that t-test value is -0.39 and p-value is 0.8, which shows that there is no significant difference between factors necessitating of the commercial banks and manufacturing firms’ involvement in CSR. The research recommends that corporate organizations should give attention to CSR initiatives as these lead to improvement of customers loyalty, improvement of the positive image of the organization, improved relationship with local communities,   and enhances shareholders values as well as improved relations with public authorities amongst others.

  15. Manufacturing technology of AS-SOFC prepared with different commercially available precursors

    Directory of Open Access Journals (Sweden)

    Kawalec M.

    2016-01-01

    Full Text Available Fuel cells are devices converting the chemical energy into the electrical energy and heat as result of the electrochemical reaction between gaseous fuel and a gas oxidant in flameless combustion process. Because of omission of thermo-mechanical steps that are present in any traditional energy conversion technology (e.g. gas turbine fuel cells show increased efficiency in comparison. Compact sizes and modular scalability predestines this technology for distributed energy generation including but not limited to renewable energy sources (e.g. wind, solar. Fuel cells technology also addresses other very important part of distributed renewable energy generation. Because of the unreliable energy production rates and the usual for renewable energy sources mismatch between energy supply and demand, some sort of energy storage is needed to store surplus of produced energy and release it when needed. Reversible fuel cells, that generate hydrogen from available surplus of energy and then generate energy from that stored fuel when needed are cheaper and more ecologically friendly alternative to usually used batteries. This technology is still under development, including research at IEn OC CEREL. In the early development of reversible fuel cells, new types of nickel oxide and porosity forming carbon was evaluated for this task. This work compares the electrical and mechanical parameters of SOFC manufactured with JT Backer NiO and Carbon Polska carbon with cells made from other commercially available materials. Based on evaluated quality, purity, availability and cost, following materials were selected for comparison: Novamet NiO, 99,9 % pure, grain size 1-2 µm and Aldrich carbon with parameters similar to graphite used previously. Preliminary tests show clear changes in the microstructural, mechanical and electrical parameters.

  16. The application of welding technology in power plant manufacture

    International Nuclear Information System (INIS)

    Price, A.T.; Chew, B.

    1989-02-01

    A strategy is presented for the application of welding technology in the manufacture of power plant. A flow chart description is adopted in the present paper to provide a general framework outlining the sequence of activities leading to manufacture. The broad chronological order of events is treated under the three headings, Component Design, Welding Development, and Implementation. Important factors that have to be considered at each of these stages are shown in subsidiary flow charts together with short notes to provide context and an aide memoire for those involved in welding technology. (author)

  17. Intersatellite link application to commercial communications satellites

    Science.gov (United States)

    Lee, Young S.; Atia, Ali E.; Ponchak, Denise S.

    1988-01-01

    The fundamental characteristics of intersatellite link (ISL) systems, and their application to domestic, regional, and global satellite communications, are described. The quantitative advantages of using ISLs to improve orbit utilization, spectrum occupancy, transmission delay (compared to multi-hop links), coverage, and connectivity, and to reduce the number of earth station antennas, are also presented. Cost-effectiveness and other systems benefits of using ISLs are identified, and the technical and systems planning aspects of ISL systems implementation are addressed.

  18. BENCHMARKING AND CONFIGURATION OF OPENSOURCE MANUFACTURING EXECUTION SYSTEM (MES APPLICATION

    Directory of Open Access Journals (Sweden)

    Ganesha Nur Laksmana

    2013-05-01

    Full Text Available Information now is an important element to every growing industry in the world. Inorder to keep up with other competitors, endless improvements in optimizing overall efficiency areneeded. There still exist barriers that separate departments in PT. XYZ and cause limitation to theinformation sharing in the system. Open-Source Manufacturing Execution System (MES presentsas an IT-based application that offers wide variety of customization to eliminate stovepipes bysharing information between departments. Benchmarking is used to choose the best Open-SourceMES Application; and Dynamic System Development Method (DSDM is adopted as this workguideline. As a result, recommendations of the chosen Open-Source MES Application arerepresented.Keywords: Manufacturing Execution System (MES; Open Source; Dynamic SystemDevelopment Method (DSDM; Benchmarking; Configuration

  19. Commercial applications of food ionization in France

    International Nuclear Information System (INIS)

    Santos, Pierre-Louis

    1994-01-01

    Due to the long history of nuclear energy in France, French public is not frightened by nuclear applications in its everyday life. The first industrial initiative on food ionization dates back to 1956. In 1980, the Joint Expert Committee on Food Ionization concluded that food ionization up to a certain maximum dose presented neither toxicological nor nutritional hazard. This opened the new era for the industrial development. But in 1988, a draft directive to harmonize national legislations was issued by the Commission of European Communities. This stopped many industrial initiatives due to uncertainty. It is estimated that nearly 14,000 tons of various food items have been ionized in France in 1991. About 40% are spices, followed by dry fruit, vegetables, and deboned poultry meat. Most of the present applications are intended to eliminate microorganisms. In 1992, 8 industrial facilities were in operation, mostly using gamma sources. Local research associations were founded to promote food ionization. Food ionization development in the past 30 years has been rapid and important, but the future of this process depends on the European harmonization of legislations. (K.I.)

  20. Apply Pesticides Correctly: A Guide for Commercial Applicators.

    Science.gov (United States)

    Environmental Protection Agency, Washington, DC.

    This document provides practical information needed by commercial pesticide applicators to meet the minimum Federal regulation requirements for the use of various pesticides. The text and accompanying illustrations cover the seven major topics of pests, pest control, pesticides, labels and labeling, using pesticides safely, application equipment,…

  1. Commercial application of bacterial heap leaching in Ganzhou uranium mine

    International Nuclear Information System (INIS)

    Liu Jian; Fan Baotuan; Meng Yunsheng; Xiao Jinfeng; Chen Sencai; Wu Jinjing; Liu Chengwu; Wu Yichang; Zeng Ruilong

    2003-01-01

    In this paper the situation of commercial application on bacterial heap leaching in Ganzhou Uranium Mine is introduced, and the construction of biomembrane oxidizing tank, regeneration and recycled utilization of barren solution are summarized. Total five heaps, 18436 t, uranium ore are leached by bacteria during the half of a year. The result is consistent with that of commercial experiment. The technology of bacterial heap leaching is more perfected

  2. Manufacturing Steps for Commercial Production of Nano-Structure Capacitors Final Report CRADA No. TC02159.0

    Energy Technology Data Exchange (ETDEWEB)

    Barbee, T. W. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Schena, D. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States)

    2017-08-29

    This was a collaborative effort between Lawrence Livermore National Security, LLC as manager and operator of Lawrence Livermore National Laboratory (LLNL) and TroyCap LLC, to develop manufacturing steps for commercial production of nano-structure capacitors. The technical objective of this project was to demonstrate high deposition rates of selected dielectric materials which are 2 to 5 times larger than typical using current technology.

  3. Implementing high-temperature short-time media treatment in commercial-scale cell culture manufacturing processes.

    Science.gov (United States)

    Pohlscheidt, Michael; Charaniya, Salim; Kulenovic, Fikret; Corrales, Mahalia; Shiratori, Masaru; Bourret, Justin; Meier, Steven; Fallon, Eric; Kiss, Robert

    2014-04-01

    The production of therapeutic proteins by mammalian cell culture is complex and sets high requirements for process, facility, and equipment design, as well as rigorous regulatory and quality standards. One particular point of concern and significant risk to supply chain is the susceptibility to contamination such as bacteria, fungi, mycoplasma, and viruses. Several technologies have been developed to create barriers for these agents to enter the process, e.g. filtration, UV inactivation, and temperature inactivation. However, if not implemented during development of the manufacturing process, these types of process changes can have significant impact on process performance if not managed appropriately. This article describes the implementation of the high-temperature short-time (HTST) treatment of cell culture media as an additional safety barrier against adventitious agents during the transfer of a large-scale commercial cell culture manufacturing process. The necessary steps and experiments, as well as subsequent results during qualification runs and routine manufacturing, are shown.

  4. Application of Additive Manufacturing in Oral and Maxillofacial Surgery.

    Science.gov (United States)

    Farré-Guasch, Elisabet; Wolff, Jan; Helder, Marco N; Schulten, Engelbert A J M; Forouzanfar, Tim; Klein-Nulend, Jenneke

    2015-12-01

    Additive manufacturing is the process of joining materials to create objects from digital 3-dimensional (3D) model data, which is a promising technology in oral and maxillofacial surgery. The management of lost craniofacial tissues owing to congenital abnormalities, trauma, or cancer treatment poses a challenge to oral and maxillofacial surgeons. Many strategies have been proposed for the management of such defects, but autogenous bone grafts remain the gold standard for reconstructive bone surgery. Nevertheless, cell-based treatments using adipose stem cells combined with osteoconductive biomaterials or scaffolds have become a promising alternative to autogenous bone grafts. Such treatment protocols often require customized 3D scaffolds that fulfill functional and esthetic requirements, provide adequate blood supply, and meet the load-bearing requirements of the head. Currently, such customized 3D scaffolds are being manufactured using additive manufacturing technology. In this review, 2 of the current and emerging modalities for reconstruction of oral and maxillofacial bone defects are highlighted and discussed, namely human maxillary sinus floor elevation as a valid model to test bone tissue-engineering approaches enabling the application of 1-step surgical procedures and seeding of Good Manufacturing Practice-level adipose stem cells on computer-aided manufactured scaffolds to reconstruct large bone defects in a 2-step surgical procedure, in which cells are expanded ex vivo and seeded on resorbable scaffolds before implantation. Furthermore, imaging-guided tissue-engineering technologies to predetermine the surgical location and to facilitate the manufacturing of custom-made implants that meet the specific patient's demands are discussed. The potential of tissue-engineered constructs designed for the repair of large oral and maxillofacial bone defects in load-bearing situations in a 1-step surgical procedure combining these 2 innovative approaches is

  5. Facility overview for commercial application of selected Rocky Flats facilities

    International Nuclear Information System (INIS)

    1996-11-01

    The purpose of this Facility Overview is to support the Rocky Flats Local Impacts Initiative's Request for Interest, to solicit interest from commercial corporations for utilizing buildings 865 and 883, and the equipment contained within each building, for a commercial venture. In the following sections, this document describes the Rocky Flats Site, the buildings available for lease, the equipment within these buildings, the site services available to a tenant, the human resources available to support operations in buildings 865 and 883, and the environmental condition of the buildings and property. In addition, a brief description is provided of the work performed to date to explore the potential products that might be manufactured in Buildings 865 and 883, and the markets for these products

  6. Dendritic cells for active immunotherapy: optimizing design and manufacture in order to develop commercially and clinically viable products.

    Science.gov (United States)

    Nicolette, C A; Healey, D; Tcherepanova, I; Whelton, P; Monesmith, T; Coombs, L; Finke, L H; Whiteside, T; Miesowicz, F

    2007-09-27

    Dendritic cell (DC) active immunotherapy is potentially efficacious in a broad array of malignant disease settings. However, challenges remain in optimizing DC-based therapy for maximum clinical efficacy within manufacturing processes that permit quality control and scale-up of consistent products. In this review we discuss the critical issues that must be addressed in order to optimize DC-based product design and manufacture, and highlight the DC based platforms currently addressing these issues. Variables in DC-based product design include the type of antigenic payload used, DC maturation steps and activation processes, and functional assays. Issues to consider in development include: (a) minimizing the invasiveness of patient biological material collection; (b) minimizing handling and manipulations of tissue at the clinical site; (c) centralized product manufacturing and standardized processing and capacity for commercial-scale production; (d) rapid product release turnaround time; (e) the ability to manufacture sufficient product from limited starting material; and (f) standardized release criteria for DC phenotype and function. Improvements in the design and manufacture of DC products have resulted in a handful of promising leads currently in clinical development.

  7. Agglomeration, isolation and dissolution of commercially manufactured silver nanoparticles in aqueous environments

    International Nuclear Information System (INIS)

    Elzey, Sherrie; Grassian, Vicki H.

    2010-01-01

    The increasing use of manufactured nanoparticles ensures these materials will make their way into the environment. Silver nanoparticles in particular, due to use in a wide range of applications, have the potential to get into water systems, e.g., drinking water systems, ground water systems, estuaries, and/or lakes. One important question is what is the chemical and physical state of these nanoparticles in water? Are they present as isolated particles, agglomerates or dissolved ions, as this will dictate their fate and transport. Furthermore, does the chemical and physical state of the nanoparticles change as a function of size or differ from micron-sized particles of similar composition? In this study, an electrospray atomizer coupled to a scanning mobility particle sizer (ES-SMPS) is used to investigate the state of silver nanoparticles in water and aqueous nitric acid environments. Over the range of pH values investigated, 0.5-6.5, silver nanoparticles with a bimodal primary particle size distribution with the most intense peak at 5.0 ± 7.4 nm, as determined from transmission electron microscopy (TEM), show distinct size distributions indicating agglomeration between pH 6.5 and 3 and isolated nanoparticles at pH values from 2.5 to 1. At the lowest pH investigated, pH 0.5, there are no peaks detected by the SMPS, indicating complete nanoparticle dissolution. Further analysis of the solution shows dissolved Ag ions at a pH of 0.5. Interestingly, silver nanoparticle dissolution shows size dependent behavior as larger, micron-sized silver particles show no dissolution at this pH. Environmental implications of these results are discussed.

  8. Agglomeration, isolation and dissolution of commercially manufactured silver nanoparticles in aqueous environments

    Energy Technology Data Exchange (ETDEWEB)

    Elzey, Sherrie; Grassian, Vicki H., E-mail: vicki-grassian@uiowa.ed [University of Iowa, Department of Chemical and Biochemical Engineering (United States)

    2010-06-15

    The increasing use of manufactured nanoparticles ensures these materials will make their way into the environment. Silver nanoparticles in particular, due to use in a wide range of applications, have the potential to get into water systems, e.g., drinking water systems, ground water systems, estuaries, and/or lakes. One important question is what is the chemical and physical state of these nanoparticles in water? Are they present as isolated particles, agglomerates or dissolved ions, as this will dictate their fate and transport. Furthermore, does the chemical and physical state of the nanoparticles change as a function of size or differ from micron-sized particles of similar composition? In this study, an electrospray atomizer coupled to a scanning mobility particle sizer (ES-SMPS) is used to investigate the state of silver nanoparticles in water and aqueous nitric acid environments. Over the range of pH values investigated, 0.5-6.5, silver nanoparticles with a bimodal primary particle size distribution with the most intense peak at 5.0 {+-} 7.4 nm, as determined from transmission electron microscopy (TEM), show distinct size distributions indicating agglomeration between pH 6.5 and 3 and isolated nanoparticles at pH values from 2.5 to 1. At the lowest pH investigated, pH 0.5, there are no peaks detected by the SMPS, indicating complete nanoparticle dissolution. Further analysis of the solution shows dissolved Ag ions at a pH of 0.5. Interestingly, silver nanoparticle dissolution shows size dependent behavior as larger, micron-sized silver particles show no dissolution at this pH. Environmental implications of these results are discussed.

  9. Transferring diffractive optics from research to commercial applications: Part II - size estimations for selected markets

    Science.gov (United States)

    Brunner, Robert

    2014-04-01

    In a series of two contributions, decisive business-related aspects of the current process status to transfer research results on diffractive optical elements (DOEs) into commercial solutions are discussed. In part I, the focus was on the patent landscape. Here, in part II, market estimations concerning DOEs for selected applications are presented, comprising classical spectroscopic gratings, security features on banknotes, DOEs for high-end applications, e.g., for the semiconductor manufacturing market and diffractive intra-ocular lenses. The derived market sizes are referred to the optical elements, itself, rather than to the enabled instruments. The estimated market volumes are mainly addressed to scientifically and technologically oriented optical engineers to serve as a rough classification of the commercial dimensions of DOEs in the different market segments and do not claim to be exhaustive.

  10. Application of adaptive antenna techniques to future commercial satellite communication

    Science.gov (United States)

    Ersoy, L.; Lee, E. A.; Matthews, E. W.

    1987-01-01

    The purpose of this contract was to identify the application of adaptive antenna technique in future operational commercial satellite communication systems and to quantify potential benefits. The contract consisted of two major subtasks. Task 1, Assessment of Future Commercial Satellite System Requirements, was generally referred to as the Adaptive section. Task 2 dealt with Pointing Error Compensation Study for a Multiple Scanning/Fixed Spot Beam Reflector Antenna System and was referred to as the reconfigurable system. Each of these tasks was further sub-divided into smaller subtasks. It should also be noted that the reconfigurable system is usually defined as an open-loop system while the adaptive system is a closed-loop system. The differences between the open- and closed-loop systems were defined. Both the adaptive and reconfigurable systems were explained and the potential applications of such systems were presented in the context of commercial communication satellite systems.

  11. Current state of commercial radiation detection equipment for homeland security applications

    International Nuclear Information System (INIS)

    Klann, R.T.; Shergur, J.; Mattesich, G.

    2009-01-01

    With the creation of the U.S. Department of Homeland Security (DHS) came the increased concern that terrorist groups would attempt to manufacture and use an improvised nuclear device or radiological dispersal device. As such, a primary mission of DHS is to protect the public against the use of these devices and to assist state and local responders in finding, locating, and identifying these types of devices and materials used to manufacture these devices. This assistance from DHS to state and local responders comes in the form of grant money to procure radiation detection equipment. In addition to this grant program, DHS has supported the development of American National Standards Institute standards for radiation detection equipment and has conducted testing of commercially available instruments. This paper identifies the types and kinds of commercially available equipment that can be used to detect and identify radiological material - for use in traditional search applications as well as primary and secondary screening of personnel, vehicles, and cargo containers. In doing so, key considerations for the conduct of operations are described as well as critical features of the instruments for specific applications. The current state of commercial instruments is described for different categories of detection equipment including personal radiation detectors, radioisotope identifiers, man-portable detection equipment, and radiation portal monitors. In addition, emerging technologies are also discussed, such as spectroscopic detectors and advanced spectroscopic portal monitors

  12. An Assessment of RFID Applications in Manufacturing Companies

    Directory of Open Access Journals (Sweden)

    Gładysz Bartłomiej

    2015-12-01

    Full Text Available The meaning of Cyber Physical Systems and an Internet of Things with indication of RFID position in those concepts was outlined. Research program related to assessment of RFID technology was presented. Author deducted on problems related to RFID implementations and RFID essentially for logistics of manufacturing companies. Research goals and problems were formulated. Tools, techniques, models and methods that could be utilized were proposed and discussed. Research was focused on design of a new method to support early decision making phases for RFID application in logistics of manufacturing companies. Author stated that literature and practice lacks of complex method to answer if RFID is strategically important for the company, which processes should be RFID-supported, how RFID-supported processes should be designed and if RFID-support is rational. Framework for assessment of RFID technology with illustrative example was discussed.

  13. MAIT application to the analysis of commercial power plants

    International Nuclear Information System (INIS)

    Goldman, L.A.; McDaniel, T.L.; Chapman, L.D.; Stack, D.

    1981-01-01

    This paper discusses a study which was conducted for the U.S. Nuclear Regulatory Commission (NRC) to determine the applicability of the Matrix Analysis of the Insider Threat (MAIT) code to the analysis of sabotage vulnerabilities of commercial power reactors. The sabotage of concern was the initiation of a release of radioactivity in excess of 10 CFR 100 guidelines. 5 refs

  14. Usage of Commercial Grade Programmable Digital Systems in Safety Related Applications

    International Nuclear Information System (INIS)

    Mandic, D.

    2006-01-01

    This paper explains methods and conditions, which if completely and correctly fulfilled, enable an operating NPP (Nuclear Power Plant) licensed and operating in accordance with the US codes and US regulatory requirements to use a commercial grade programmable digital device (PLC - Programmable Digital Controller, digital controller, digital computer or process computer) in a safety related application in a NPP. In mid 80's, when an intensive construction cycle of the new NPPs in the U.S.A. was completed, many equipment manufacturers either disappeared from the market or they abandoned their product lines that were designed and manufactured under 10 CFR Part 50 Appendix B quality assurance program. The quality assurance as defined by 10 CFR Part 50 Appendix B comprises all those planned and systematic actions necessary to provide adequate confidence that a Structure, System or Component (SSC) will perform satisfactorily in service . The operating NPPs faced the problem related to the availability of qualified equipment, components and spare parts. The US NRC (Nuclear Regulatory Commission) recognized that problem timely (Oct. 1978 revision of 10CFR21) and required a commercial grade item to be dedicated before it could be used as a basic component. A special process named Dedication of CGI - Commercial Grade Items if conducted properly, provides reasonable assurance that a commercial grade item to be used as a basic component will perform its intended safety related function and, in this respect, is deemed equivalent to an item designed and manufactured under 10 CFR Part 50 Appendix B. After that, the Dedication of CGI has been widely used mostly for relatively simple mechanical, electrical, and IandC components and spare parts. In order to provide guidance to the dedication process, EPRI has issued two documents (EPRI NP-5652 and Supplemental Guidance for EPRI NP-5652). All nuclear power plants, which comply with the US nuclear regulatory requirements, hindered as

  15. The Mobile Application Social Mode of Manufacturing Enterprise under the Environment of Mobile Internet

    Directory of Open Access Journals (Sweden)

    Zuo Cen

    2017-01-01

    Full Text Available The rapid development of the mobile internet, mobile communication technology and mobile terminal stimulate demand of mobile application in manufacturing enterprises, which makes the enterprise implement the mobile ERP. The implementation of mobile ERP changes the internal application management of manufacturing enterprises to social applications. We analyse the driving factors of implementing the mobile application social mode considering the complexity of organization relations and business processes of manufacturing enterprise. And then the mobile application social mode of the manufacturing enterprise is built based on mobile internet. Finally, we present the management strategies of the mobile application social network to provide references for the manufacturing enterprise.

  16. Short communication: The effects of frozen storage on the survival of probiotic microorganisms found in traditionally and commercially manufactured kefir.

    Science.gov (United States)

    O'Brien, K V; Aryana, K J; Prinyawiwatkul, W; Ordonez, K M Carabante; Boeneke, C A

    2016-09-01

    Kefir is a fermented milk traditionally made from a unique starter culture, which consists of numerous bacteria and yeast species bound together in an exopolysaccharide matrix produced by certain lactic acid bacteria. Many health benefits are associated with traditionally produced kefir; however, bulging and leaking packaging, caused by secondary yeast fermentation during storage, has limited large-scale manufacture. Commercial kefir products have been designed to reduce these effects by using a pure starter culture consisting of a mixture of bacteria and yeast species that give a flavor similar to traditional kefir, but some health benefits may be lost in commercial production due to reduced microbial diversity and lack of beneficial exopolysaccharides. In this study, traditional and commercial kefir was frozen to study the effects of frozen storage on the viability of probiotic bacteria over time. Traditional kefir was prepared by inoculating 1L of pasteurized whole goat milk with approximately 30g of kefir grains. Commercial kefir was prepared by inoculating 1L of full-fat, pasteurized goat milk with a commercial kefir starter. The milk was allowed to ferment at room temperature (24-28°C) until pH 4.6 was reached. Samples were frozen (-8 to -14°C) immediately following the completion of fermentation and were thawed and plated for lactobacilli, lactococci, and yeasts on d 0, 7, 14, and 30 of frozen storage. Lactobacilli, lactococci, and yeasts were significantly reduced in number during frozen storage; however, the traditionally produced kefir was shown to have significantly higher counts of bacteria and yeast at each sampling. We concluded that frozen storage and the development of frozen kefir products could eliminate most packaging concerns associated with the large-scale manufacture of traditionally produced kefir, resulting in increased production and marketability of this healthful product. Copyright © 2016 American Dairy Science Association. Published

  17. Layered Thermal Insulation Systems for Industrial and Commercial Applications

    Science.gov (United States)

    Fesmire, James E.

    2015-01-01

    From the high performance arena of cryogenic equipment, several different layered thermal insulation systems have been developed for industrial and commercial applications. In addition to the proven areas in cold-work applications for piping and tanks, the new Layered Composite Insulation for Extreme Environments (LCX) has potential for broader industrial use as well as for commercial applications. The LCX technology provides a unique combination of thermal, mechanical, and weathering performance capability that is both cost-effective and enabling. Industry applications may include, for example, liquid nitrogen (LN2) systems for food processing, liquefied natural gas (LNG) systems for transportation or power, and chilled water cooling facilities. Example commercial applications may include commercial residential building construction, hot water piping, HVAC systems, refrigerated trucks, cold chain shipping containers, and a various consumer products. The LCX system is highly tailorable to the end-use application and can be pre-fabricated or field assembled as needed. Product forms of LCX include rigid sheets, semi-flexible sheets, cylindrical clam-shells, removable covers, or flexible strips for wrapping. With increasing system control and reliability requirements as well as demands for higher energy efficiencies, thermal insulation in harsh environments is a growing challenge. The LCX technology grew out of solving problems in the insulation of mechanically complex cryogenic systems that must operate in outdoor, humid conditions. Insulation for cold work includes equipment for everything from liquid helium to chilled water. And in the middle are systems for LNG, LN2, liquid oxygen (LO2), liquid hydrogen (LH2) that must operate in the ambient environment. Different LCX systems have been demonstrated for sub-ambient conditions but are capable of moderately high temperature applications as well.

  18. 10 CFR 32.72 - Manufacture, preparation, or transfer for commercial distribution of radioactive drugs containing...

    Science.gov (United States)

    2010-01-01

    ... radioactive drug; and the shielding provided by the packaging to show it is appropriate for the safe handling... constructed of lead, glass, plastic, or other material, of a radioactive drug to be transferred for commercial...

  19. Applications Of Laser Processing For Automotive Manufacturing In Japan

    Science.gov (United States)

    Ito, Masashi; Ueda, Katsuhiko; Takagi, Soya

    1986-11-01

    Recently in Japan, laser processing is increasingly being employed for production, so that laser cutting, laser welding and other laser material processing have begun to be used in various industries. As a result, the number of lasers sold has been increasing year by year in Japan. In the Japanese automotive industry, a number applications have been introduced in laboratories and production lines. In this paper, several current instances of such laser applications will be introduced. In the case of welding, studies have been conducted on applying laser welding to automatic transmission components, in place of electron beam welding. Another example of application, the combination of lasers and robots to form highly flexible manufacturing systems, has been adopted for trimming steel panel and plastic components.

  20. Applications of additive manufacturing in dentistry: A review.

    Science.gov (United States)

    Bhargav, Aishwarya; Sanjairaj, Vijayavenkatraman; Rosa, Vinicius; Feng, Lu Wen; Fuh Yh, Jerry

    2017-07-24

    Additive manufacturing (AM) or 3D printing has been hailed as the third industrial revolution as it has caused a paradigm shift in the way objects have been manufactured. Conventionally, converting a raw material to a fully finished and assembled, usable product comprises several steps which can be eliminated by using this process as functional products can be created directly from the raw material at a fraction of the time originally consumed. Thus, AM has found applications in several sectors including automotive, aerospace, printed electronics, and healthcare. AM is increasingly being used in the healthcare sector, given its potential to fabricate patient-specific customized implants with required accuracy and precision. Implantable heart valves, rib cages, and bones are some of the examples where AM technologies are used. A vast variety of materials including ceramics, metals, polymers, and composites have been processed to fabricate intricate implants using 3D printing. The applications of AM in dentistry include maxillofacial implants, dentures, and other prosthetic aids. It may also be used in surgical training and planning, as anatomical models can be created at ease using AM. This article gives an overview of the AM process and reviews in detail the applications of 3D printing in dentistry. © 2017 Wiley Periodicals, Inc. J Biomed Mater Res Part B: Appl Biomater, 2017. © 2017 Wiley Periodicals, Inc.

  1. Case Study: Commercialization of sweet sorghum juice clarification for large-scale syrup manufacture

    Science.gov (United States)

    The precipitation and burning of insoluble granules of starch from sweet sorghum juice on heating coils prevented the large scale manufacture of syrup at a new industrial plant in Missouri, USA. To remove insoluble starch granules, a series of small and large-scale experiments were conducted at the...

  2. Application of a mathematical model for ergonomics in lean manufacturing.

    Science.gov (United States)

    Botti, Lucia; Mora, Cristina; Regattieri, Alberto

    2017-10-01

    The data presented in this article are related to the research article "Integrating ergonomics and lean manufacturing principles in a hybrid assembly line" (Botti et al., 2017) [1]. The results refer to the application of the mathematical model for the design of lean processes in hybrid assembly lines, meeting both the lean principles and the ergonomic requirements for safe assembly work. Data show that the success of a lean strategy is possible when ergonomics of workers is a parameter of the assembly process design.

  3. Positron emitting radionuclides: manufacturing, labelling and examples of medical applications

    International Nuclear Information System (INIS)

    Comar, D.; Maziere, M.; Berger, G.; Crouzel, C.; Soussaline, F.; Kellershohn, C.

    1979-01-01

    The only radioisotopes of carbon, oxygen and nitrogen which can be used in medicine are positrons emitters. They may be incorporated in organic molecules and detected in vivo by quantitative emission tomography. The manufacture of these short lived radioisotopes need a cyclotron to be set up in a hospital. The main procedures for making these radioisotopes are described so as their incorporation in complex molecules. Some medical applications in the field of the brain blood-flow, and oxygen consumption, the cerebral amino-acids metabolism and the brain distribution of psychoactive drugs are described [fr

  4. Image slicer manufacturing: from space application to mass production

    Science.gov (United States)

    Bonneville, Christophe; Cagnat, Jean-François; Laurent, Florence; Prieto, Eric; Ancourt, Gérard

    2004-09-01

    This presentation aims to show technical and industrial inputs to be taking into account for Image Slicer systems design and development for different types of projects from space application to mass production for multi-IFU instruments. Cybernétix has a strong experience of precision optics assembled thanks to molecular adhesion and have already manufactured 6 prototypes of image slicer subsystem (prototypes of NIRSPEC-IFU, IFS for JWST, MUSE ...) in collaboration with the Laboratoire d"Astrophysique de Marseille (LAM) and the Centre de Recherche Astronomique de Lyon (CRAL). After a brief presentation of the principle of manufacturing and assembly, we will focus on the different performances achieved in our prototypes of slicer mirrors, pupil and slit mirrors lines: an accuracy on centre of curvature position better than 15 arsec has been obtained for a stack of 30 slices. The contribution of the slice stacking to this error is lower than 4 arcsec. In spite of very thin surfaces (~ 0.9 x 40 mm for instance), a special process allows to guarantee a surface roughness about 5 nm and very few digs on the slice borders. The WFE of the mini-mirror can also be measured at a stage of the manufacturing. Different environmental tests have shown the withstanding of these assemblies to cryogenic temperature (30 K). Then, we will describe the different solutions (spherical, flat, cylindrical surfaces) and characteristics of an image slicer that can influence difficulties of manufacturing and metrology, cost, schedule and risks with regard to fabrication. Finally, the study of a mass production plan for MUSE (CRAL) composed of 24 Image Slicers of 38 slices, that"s to say 912 slices, will be exposed as an example of what can be do for multi-module instruments.

  5. New developments in nickel-hydrogen cell and battery design for commercial applications

    Energy Technology Data Exchange (ETDEWEB)

    Caldwell, D.B.; Fox, C.L.; Miller, L.E. [Eagle-Picher Industries, Inc., Joplin, MO (United States)

    1997-12-31

    Nickel-hydrogen (NiH{sub 2}) battery systems were first developed for space applications more than 20 years ago. Currently, they are being manufactured for commercial, terrestrial applications. The battery is ideal for commercial terrestrial energy storage applications because it offers a better potential cycle life than any other battery system and is maintenance free. A selection of low-cost components, electrodes, cell designs and battery designs are being tested to determine their feasibility for commercial applications. The dependent pressure vessel (DPV) design, developed by Eagle-Picher Industries, is the newest step in the continued development and evolution of the NiH{sub 2} system. The unique feature of the DPV cell design is the prismatic electrode stack which is more efficient than the cylindrical electrode stack. The electrode stack is the electrochemically active part of the cell. It contains nickel and hydrogen electrodes interspersed with an absorbent separator. DPV cells of two sizes, 40 and 60 Ah cells, have been developed. The DPV cell offers high specific energy at a reduced cost. The advanced DPV design also offers an efficient mechanical, electrical and thermal configuration and a reduced parts count. The design promotes compact, minimum volume packaging and weight efficiency. 8 refs., 7 figs.

  6. Nuclear Analytical Techniques for Commercial Applications in China

    International Nuclear Information System (INIS)

    Chai, Z.; Zhang, Z.; Feng, S.; Yang, J.; Ouyang, H.; Feng, X.; Mao, X.

    2013-01-01

    Since the establishment of the first Chinese nuclear reactor and accelerator in 1958, the nuclear analytical techniques (NATs) in China have dramatically developed in past half century. Nowadays 10 research nuclear reactors and over 100 small accelerators are available in China. Roughly, about 50 % of the machine time is applied for commercial purpose at the moment. The versatile nuclear analytical methods, mainly NAA, PIXE, XRF, etc., in China have been and are being applied widely and extensively in the following three fields: scientific, training, and commercial. This paper will briefly describe the past experience and present status about NATs for commercial applications. Some practical examples to demonstrate the role of NATs in this aspect will be given as well. Basically, the NATs used for the commercial applications in China can be divided into two types, i.e. off-line and on-line. The former mainly includes instrumental neutron activation analysis (INAA) for compositional determination, particle induced X-ray emission (PIXE) also for compositional analysis, accelerator-based mass-spectrometry (AMS) for analysis of C-14, Be-7, Cl-36 and other long-lived radioactive nuclides, solid state nuclear track detector

  7. Polycrystalline Diamond Coating of Additively Manufactured Titanium for Biomedical Applications.

    Science.gov (United States)

    Rifai, Aaqil; Tran, Nhiem; Lau, Desmond W; Elbourne, Aaron; Zhan, Hualin; Stacey, Alastair D; Mayes, Edwin L H; Sarker, Avik; Ivanova, Elena P; Crawford, Russell J; Tran, Phong A; Gibson, Brant C; Greentree, Andrew D; Pirogova, Elena; Fox, Kate

    2018-03-14

    Additive manufacturing using selective laser melted titanium (SLM-Ti) is used to create bespoke items across many diverse fields such as medicine, defense, and aerospace. Despite great progress in orthopedic implant applications, such as for "just in time" implants, significant challenges remain with regards to material osseointegration and the susceptibility to bacterial colonization on the implant. Here, we show that polycrystalline diamond coatings on these titanium samples can enhance biological scaffold interaction improving medical implant applicability. The highly conformable coating exhibited excellent bonding to the substrate. Relative to uncoated SLM-Ti, the diamond coated samples showed enhanced mammalian cell growth, enriched apatite deposition, and reduced microbial S. aureus activity. These results open new opportunities for novel coatings on SLM-Ti devices in general and especially show promise for improved biomedical implants.

  8. 76 FR 39127 - Manufacturer of Controlled Substances; Notice of Application

    Science.gov (United States)

    2011-07-05

    ... Administration (DEA) to be registered as a bulk manufacturer of Remifentanil (9739) the basic class of controlled substance in schedule II. The company plans to utilize this facility to manufacture small quantities of the... primary manufacturing facility in West Deptford, New Jersey. The controlled substances manufactured in...

  9. 26 CFR 301.6511(e)-1 - Special rules applicable to manufactured sugar.

    Science.gov (United States)

    2010-04-01

    ... 26 Internal Revenue 18 2010-04-01 2010-04-01 false Special rules applicable to manufactured sugar... Assessment and Collection § 301.6511(e)-1 Special rules applicable to manufactured sugar. (a) Use as... the person entitled thereto. Such right accrues as of the date the manufactured sugar, or article...

  10. 40 CFR 417.80 - Applicability; description of the manufacture of liquid soaps subcategory.

    Science.gov (United States)

    2010-07-01

    ... manufacture of liquid soaps subcategory. 417.80 Section 417.80 Protection of Environment ENVIRONMENTAL... CATEGORY Manufacture of Liquid Soaps Subcategory § 417.80 Applicability; description of the manufacture of liquid soaps subcategory. The provisions of this subpart are applicable to discharges resulting from the...

  11. 40 CFR 426.100 - Applicability; description of the glass tubing (Danner) manufacturing subcategory.

    Science.gov (United States)

    2010-07-01

    ... glass tubing (Danner) manufacturing subcategory. 426.100 Section 426.100 Protection of Environment... CATEGORY Glass Tubing (Danner) Manufacturing Subcategory § 426.100 Applicability; description of the glass tubing (Danner) manufacturing subcategory. The provisions of this subpart are applicable to discharges...

  12. Survey of US Department of Defense Manufacturing Technology Program activities applicable to civilian manufacturing industries. Final report

    Energy Technology Data Exchange (ETDEWEB)

    Azimi, S.A.; Conrad, J.L.; Reed, J.E.

    1985-03-01

    Intent of the survey was to identify and characterize activities potentially applicable to improving energy efficiency and overall productivity in the civilian manufacturing industries. The civilian industries emphasized were the general manufacturing industries (including fabricated metals, glass, machinery, paper, plastic, textile, and transportation equipment manufacturing) and the primary metals industries (including primary aluminum, copper, steel, and zinc production). The principal steps in the survey were to: develop overview taxonomies of the general manufacturing and primary metals industries as well as specific industry taxonomies; identify needs and opportunities for improving process energy efficiency and productivity in the industries included; identify federal programs, capabilities, and special technical expertise that might be relevant to industry's needs and opportunities; contact federal laboratories/facilities, through visits and other forms of inquiry; prepare formatted profiles (descriptions) potentially applicable work efforts; review findings with industry; and compile and evaluate industry responses.

  13. Hide unhairing and characterization of commercial enzymes used in leather manufacture

    Directory of Open Access Journals (Sweden)

    A Dettmer

    2011-09-01

    Full Text Available The enzymatic treatment of hides in tannery processes is a promising technology. However, the reaction kinetics of commercial enzymes available to the leather industry are not fully understood and their activities have been mainly determined with model proteins such as casein as substrate, which are not of direct relevance for cattle hides. Therefore, it is important to determine their activities on collagen and keratin, the main proteins of skin, in order to use these enzymes in leather processing. This work describes the study of five proteases, used commercially in tanneries, to assess their ability to act upon collagen and keratin and to determine their unhairing. Results showed that all commercial enzymes tested had more activity on collagen than on keratin. Unhairing was also tested and four out of the five enzymes tested showed some unhairing activity. Optima of the temperature and pH of the enzymes were very similar for all five enzymes, with maximal activities around 55ºC and pH 9 to 12, respectively.

  14. Scrum application in service: analysis on an aircraft manufacturer

    Directory of Open Access Journals (Sweden)

    Stefano Petrini de Oliveira

    2015-02-01

    Full Text Available This article analyzes the application of Scrum approach in a test service area in aircraft. It is a qualitative study conducted at the largest aircraft manufacturer in Brazil. Scrum is widely used for software project management in several segments, but its features allow the use in project management in general applications, both development of products and services. This paper contributes to analyze the application for services and illustrates the Scrum use for managers. It explains the establishment, maturation, obstacles encountered and results achieved with the Scrum. The sector analyzed is the Hydro-Testing Systems and Controls Flight, responsible for performing system testing in laboratories composed of real parts and simulating systems of aircraft parts. Descriptive data were obtained through direct and interactive contact with the target situation. We sought information with the team members of testing using a questionnaire as a research tool. The application of agile approach Scrum in project management has brought good results for this testing area, subsequently for the related divisions and organization goals. It reached a better organization of management and staff, greater processing efficiency and completion targets were achieved close to that predicted. Scrum has brought transparency, since invested in increased visibility of the significant aspects of the process for all those listed. It assisted the inspections and monitoring results, propelling the guiding the process toward the goal and detecting undesirable variations and obstacles during the test campaign.

  15. Properties of Portland-Composite Cements with metakaolin: Commercial and manufactured by Thermal Activation of Serbian Kaolin Clay

    Directory of Open Access Journals (Sweden)

    Mitrovic A.

    2012-09-01

    Full Text Available Portland-composite cements (CEM II were prepared with addition of 5 to 35% of metakaolin (MK, manufactured by thermal activation/calcination of Serbian kaolin clay, and commercial matakaolin (CMK. Performance of the composite cements was evaluated, through the setting time (initial and final, compressive strengths (for ages 2, 7, 28, 90 and 180 days and soundness, and compared with control cement (Portland cement – CEM I. Setting time (initial and final is accelerated in Portlandcomposite cements, for both metakaolins used. The acceleration is higher in cement with addition of commercial metakaolin. Lower compressive strength is obtained after 2 days of curing for all Portland-composite cements in comparison with control cement, since pozzolanic reaction still did not show its effect. After 7 days, pozzolanic reaction show its effect, manifested as compressive strength increase of Portland-composite cements with addition of up to 35% of CMK, and 25% in the case of cements with MK. After 28 days compressive strength was higher than that for control cement for cements prepared with addition of CMK, and with addition of up to 25% MK. After 90 days increased compressive strength was noticed with addition of 10 - 20% of CMK, and with 10 and 15% of MK, while after 180 days addition of both metakaolins influences compressive strength decrease. The results of the soundness, 0.5 mm for CEM I, and 1.0 mm in most Portland-composite cements indicate soundness increase with addition of metakaolins. Generally, better performance of Portland-composite cements was obtained with addition of commercial metakaolin, which may be attributed to the differences in the pozzolanic activity of the applied metakaolins, 20.5 MPa and 14.9 MPa for CMK and MK, respectively. By our previous findings pozzolanic activity of the thermally activated clay may be increased by subsequent milling of the metakaolin manufactured by thermal activation process.

  16. Honeycomb technology materials, design, manufacturing, applications and testing

    CERN Document Server

    Bitzer, Tom

    1997-01-01

    Honeycomb Technology is a guide to honeycomb cores and honeycomb sandwich panels, from the manufacturing methods by which they are produced, to the different types of design, applications for usage and methods of testing the materials. It explains the different types of honeycomb cores available and provides tabulated data of their properties. The author has been involved in the testing and design of honeycomb cores and sandwich panels for nearly 30 years. Honeycomb Technology reflects this by emphasizing a `hands-on' approach and discusses procedures for designing sandwich panels, explaining the necessary equations. Also included is a section on how to design honeycomb energy absorbers and one full chapter discussing honeycomb core and sandwich panel testing. Honeycomb Technology will be of interest to engineers in the aircraft, aerospace and building industries. It will also be of great use to engineering students interested in basic sandwich panel design.

  17. Manufacturing radioactive material for medical, research and industrial applications

    International Nuclear Information System (INIS)

    Seidel, C.W.

    1992-01-01

    Hospitals, clinics and other medical complexes are among the most extensive users of radioactive material. Nuclear medicine uses radioactive solutions of Tc-99m, Tl-201, Ga-67, I-123, Xe-133 and other radiopharmaceuticals as diagnostic tools to evaluate dynamic functions of various organs in the body, detect cancerous tumors, sites of infection or other bodily dysfunctions. Examples of monitoring blood flow to the brain of a cocaine addict will be shown. Many different radionuclides are also produced for life science research and industrial applications. Some require long irradiations and are needed only periodically. Radiopharmaceutical manufactures look for reliable suppliers that can produce quality product at a reasonable cost. Worldwide production of the processed and unprocessed radionuclides and the enriched stable nuclides that are the target materials used in the accelerators and reactors around the world will be discussed. (author)

  18. 76 FR 5829 - Manufacturer of Controlled Substances; Notice of Application

    Science.gov (United States)

    2011-02-02

    ... bulk manufacturer of the following basic classes of controlled substances: Drug Schedule Marihuana.... In reference to drug code 7360 (Marihuana), the company plans to bulk manufacture cannabidiol as a...

  19. Scalable manufacturing of biomimetic moldable hydrogels for industrial applications

    Science.gov (United States)

    Yu, Anthony C.; Chen, Haoxuan; Chan, Doreen; Agmon, Gillie; Stapleton, Lyndsay M.; Sevit, Alex M.; Tibbitt, Mark W.; Acosta, Jesse D.; Zhang, Tony; Franzia, Paul W.; Langer, Robert; Appel, Eric A.

    2016-12-01

    Hydrogels are a class of soft material that is exploited in many, often completely disparate, industrial applications, on account of their unique and tunable properties. Advances in soft material design are yielding next-generation moldable hydrogels that address engineering criteria in several industrial settings such as complex viscosity modifiers, hydraulic or injection fluids, and sprayable carriers. Industrial implementation of these viscoelastic materials requires extreme volumes of material, upwards of several hundred million gallons per year. Here, we demonstrate a paradigm for the scalable fabrication of self-assembled moldable hydrogels using rationally engineered, biomimetic polymer-nanoparticle interactions. Cellulose derivatives are linked together by selective adsorption to silica nanoparticles via dynamic and multivalent interactions. We show that the self-assembly process for gel formation is easily scaled in a linear fashion from 0.5 mL to over 15 L without alteration of the mechanical properties of the resultant materials. The facile and scalable preparation of these materials leveraging self-assembly of inexpensive, renewable, and environmentally benign starting materials, coupled with the tunability of their properties, make them amenable to a range of industrial applications. In particular, we demonstrate their utility as injectable materials for pipeline maintenance and product recovery in industrial food manufacturing as well as their use as sprayable carriers for robust application of fire retardants in preventing wildland fires.

  20. Imaging requirements for medical applications of additive manufacturing.

    Science.gov (United States)

    Huotilainen, Eero; Paloheimo, Markku; Salmi, Mika; Paloheimo, Kaija-Stiina; Björkstrand, Roy; Tuomi, Jukka; Markkola, Antti; Mäkitie, Antti

    2014-02-01

    Additive manufacturing (AM), formerly known as rapid prototyping, is steadily shifting its focus from industrial prototyping to medical applications as AM processes, bioadaptive materials, and medical imaging technologies develop, and the benefits of the techniques gain wider knowledge among clinicians. This article gives an overview of the main requirements for medical imaging affected by needs of AM, as well as provides a brief literature review from existing clinical cases concentrating especially on the kind of radiology they required. As an example application, a pair of CT images of the facial skull base was turned into 3D models in order to illustrate the significance of suitable imaging parameters. Additionally, the model was printed into a preoperative medical model with a popular AM device. Successful clinical cases of AM are recognized to rely heavily on efficient collaboration between various disciplines - notably operating surgeons, radiologists, and engineers. The single main requirement separating tangible model creation from traditional imaging objectives such as diagnostics and preoperative planning is the increased need for anatomical accuracy in all three spatial dimensions, but depending on the application, other specific requirements may be present as well. This article essentially intends to narrow the potential communication gap between radiologists and engineers who work with projects involving AM by showcasing the overlap between the two disciplines.

  1. 76 FR 81979 - Manufacturer of Controlled Substances; Notice of Application

    Science.gov (United States)

    2011-12-29

    ...), the company presently manufactures a small amount of this controlled substance in bulk solely to conduct manufacturing internal process development. It is the company's intention that, when the... (1105) only, the company manufactures these controlled substances in bulk solely for distribution within...

  2. Application of mechatronic design approach in a reconfigurable manufacturing environment

    CSIR Research Space (South Africa)

    Xing, B

    2008-12-01

    Full Text Available manufacturing system (FMS) do not longer meet the requirement of modern manufacturing. DMS were designed for mass production, while FMS was designed for batch manufacturing. These systems cannot address mass customization. There is a need for greater, more...

  3. Influence of feeding thermally peroxidized soybean oil to finishing barrows on processing characteristics and shelf life of commercially manufactured bacon.

    Science.gov (United States)

    Overholt, M F; Lowell, J E; Kim, G D; Boler, D D; Kerr, B J; Dilger, A C

    2018-05-12

    Objectives were to evaluate effects of feeding soybean oil (SO) with varying levels of peroxidation on fresh belly characteristics, processing yields, and shelf life of commercially manufactured bacon stored under food-service style conditions. Fifty-six barrows were randomly assigned to 1 of 4 diets containing 10% fresh SO (22.5°C) or thermally processed SO (45°C for 288 h, 90°C for 72 h, or 180°C for 6 h), each infused with air at a rate of 15L/min. Individually housed pigs were provided ad libitum access to feed for 81 d. On d 82 pigs were slaughtered and on d 83 carcasses were fabricated and bellies collected for recording of weight, dimensions, and flop distance. Belly adipose tissue cores were collected for analysis of iodine value (IV) by near-infrared spectroscopy (NIR-IV). Bacon was manufactured at a commercial processing facility and sliced bacon was subsequently transferred to food-service style packaging and subjected to 0, 30, 60, or 90 d storage at -20°C. Stored bacon was evaluated for thiobarbituric acid reactive substances (TBARS) and trained sensory evaluation of oxidized odor and flavor. Fresh belly and bacon processing traits were analyzed as a one-way ANOVA with the fixed effect of SO; whereas, shelf life traits were analyzed as a one-way ANOVA repeated in time. There was no effect (P ≥ 0.30) of SO on belly weight, length, width, or thickness; but bellies of pigs fed 90°C SO had greater (P ≤ 0.04) flop distance (more firm) than all other SO treatments. Belly fat NIR-IV of pigs fed 90°C SO were 10.22 units less (P processed at 90°C and 180°C reduced belly adipose tissue IV, but feeding peroxidized SO did not affect processing yields or shelf life characteristics of commercially manufactured bacon.

  4. Bioreactors in tissue engineering - principles, applications and commercial constraints.

    Science.gov (United States)

    Hansmann, Jan; Groeber, Florian; Kahlig, Alexander; Kleinhans, Claudia; Walles, Heike

    2013-03-01

    Bioreactor technology is vital for tissue engineering. Usually, bioreactors are used to provide a tissue-specific physiological in vitro environment during tissue maturation. In addition to this most obvious application, bioreactors have the potential to improve the efficiency of the overall tissue-engineering concept. To date, a variety of bioreactor systems for tissue-specific applications have been developed. Of these, some systems are already commercially available. With bioreactor technology, various functional tissues of different types were generated and cultured in vitro. Nevertheless, these efforts and achievements alone have not yet led to many clinically successful tissue-engineered implants. We review possible applications for bioreactor systems within a tissue-engineering process and present basic principles and requirements for bioreactor development. Moreover, the use of bioreactor systems for the expansion of clinically relevant cell types is addressed. In contrast to cell expansion, for the generation of functional three-dimensional tissue equivalents, additional physical cues must be provided. Therefore, bioreactors for musculoskeletal tissue engineering are discussed. Finally, bioreactor technology is reviewed in the context of commercial constraints. Copyright © 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  5. Mobile Technology Applications for Manufacturing, Reduction of Muda (Waste and the Effect on Manufacturing Economy and Efficiency

    Directory of Open Access Journals (Sweden)

    Angela M Huenerfauth

    2014-10-01

    Full Text Available Mobile devices in the manufacturing setting offer mobility and information whenever and wherever it is needed; these advantages allow for a more efficient workflow and allow the user to make more informed decisions. Due to these advantages, companies are reducing muda (waste by using mobile devices (implementing Lean Manufacturing and therefore saving money. Some of the mobile applications discussed in this paper are the following: Augmented Reality for assembly training, pruefcubing, remotely-monitored shop floors, statistical process control (SPC, and change requests for construction, and the two types of muda (waste reduced by these mobile applications are “unnecessary / excess motion and defects.”

  6. Preliminary Evaluation Of Commercial Supercapacitors For Space Applications

    Science.gov (United States)

    Gineste, Valery; Loup, Didier; Mattesco, Patrick; Neugnot, Nicolas

    2011-10-01

    Supercapacitors are identified since years as a new technology enabling energy storage together with high power delivery capability to the system. A recent ESA study [1] led by Astrium has demonstrated the interest of these devices for space application, providing that reliability and end of life performances are demonstrated. A realistic commercial on the shelf (COTS) approach (or with limited design modification approved by potential suppliers) has been favoured (as for batteries). This paper presents preliminary test results done by Astrium on COTS supercapacitors: accelerated life tests, calendar life tests, technology analyses. Based on these results, assessment and lessons learnt are drawn in view of future exhaustive supercapacitor validation and future qualification.

  7. Performance measures in the earth observations commercialization applications program

    Science.gov (United States)

    Macauley, Molly K.

    1996-03-01

    Performance measures in the Earth Observations Commercialization Application Program (EOCAP) are key to its success and include net profitability; enhancements to industry productivity through generic innovations in industry practices, standards, and protocols; and documented contributions to public policy governing the newly developing remote sensing industry. Because EOCAP requires company co-funding, both parties to the agreement (the government and the corporate partner) have incentives to pursue these goals. Further strengthening progress towards these goals are requirements for business plans in the company's EOCAP proposal, detailed scrutiny given these plans during proposal selection, and regularly documented progress reports during project implementation.

  8. Extended Evaluations of the Commercial Spectrometer Systems for Safeguards Applications

    Energy Technology Data Exchange (ETDEWEB)

    Duc T. Vo

    1999-08-01

    Safeguards applications require the best of the spectrometer system with excellent resolution, stability, and throughput. Instruments must perform well in all situations and environments. Data communication to the computer should be convenient, fast, and reliable. The software should have all the necessary tools and be easy to use. Portable systems should be small in size, lightweight, and have a long battery life. Nine commercially available spectrometer systems are tested with five different germanium detectors. Considering the performance of the Digital Signal Processors (DSP), digital-based spectroscope y may become the way of future gamma-ray spectroscopy.

  9. The commissioning and acceptance of a commercially manufactured radiotherapy beam tissue compensating filter system

    International Nuclear Information System (INIS)

    Sorell, M.J.; Sorell, G.C.; Nicholls, R.L.

    1990-01-01

    The principles of tissue compensation in radiotherapy and the methods for their implementation on the GE RT/Plan computer are briefly described. The HEK Medizintechnik GmbH Medical Systems Tissue Compensator cutting device is also described, along with the tesing procedure adopted for its commissioning and quality assurance testing of the total system. The HEK machine hardware proved to be well engineered, but there were many deficiencies in the software supplied to interface it to the planning computer. Most errors were fatal to the program producing a compensator but a number of errors allowed the cutter to manufacture shapes which on close inspection turned out to be incorrect. These faults were traced to incorrect algorithms and/or incorrect software implementation. It is stressed that the software errors were entirely the responsibility of HEK and that the GE equipment and software were not deficient in any way. However, the experiences of the Adelaide group suggest that caution should be exercised when purchasing two pieces of interacting equipment from separate suppliers. 2 refs., 1 tab., 4 figs

  10. Review of Compact Commercial Accelerator Products and Applications.

    Science.gov (United States)

    Jongen, Y.

    1997-05-01

    Historically, particle accelerators were developed initially for nuclear, then for particle physics research. From this research resulted applications of accelerators in the field of medicine and industry. These application-oriented accelerators are generally built commercially, and they often emphasize other qualities than the accelerators for research. The research applications frequently require energies or beam qualities at the limit of the existing technologies. They offer the largest flexibility in term of particles and beam properties, but are more complex, more expensive and often require large and highly qualified staff to operate and maintain them. In contrast, most applications are done with low to moderate energy protons or electrons, but often with large average beam power. The accelerators are generally specialized for a specific application, and are therefore very simple and inexpensive to operate. The author will review some applications in the field of medicine, such as the production of radio-isotopes for medical diagnostic or the production of electrons, protons or fast neutron beams for cancer therapy. In the industrial field, high power electron beam are used for sterilization and for the modification of materials. Log No. 1001

  11. 40 CFR 417.60 - Applicability; description of the manufacture of soap flakes and powders subcategory.

    Science.gov (United States)

    2010-07-01

    ... manufacture of soap flakes and powders subcategory. 417.60 Section 417.60 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) EFFLUENT GUIDELINES AND STANDARDS SOAP AND DETERGENT MANUFACTURING POINT SOURCE CATEGORY Manufacture of Soap Flakes and Powders Subcategory § 417.60 Applicability...

  12. 40 CFR 417.160 - Applicability; description of the manufacture of liquid detergents subcategory.

    Science.gov (United States)

    2010-07-01

    ... manufacture of liquid detergents subcategory. 417.160 Section 417.160 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) EFFLUENT GUIDELINES AND STANDARDS SOAP AND DETERGENT MANUFACTURING POINT SOURCE CATEGORY Manufacture of Liquid Detergents Subcategory § 417.160 Applicability; description of the...

  13. Manufacturing polycrystalline pellets of natural quartz for applications in thermoluminescence dosimetry

    Energy Technology Data Exchange (ETDEWEB)

    Carvalho Junior, Alvaro Barbosa de; Khoury, Helen Jamil [Federal University of Pernambuco (UFPE), Recife, PE (Brazil). Department of Nuclear Energy; Barros, Thiago Fernandes; Guzzo, Pedro Luiz [Federal University of Pernambuco (UFPE), Recife, PE (Brazil). Department of Mining Engineering

    2012-07-15

    This paper describes the manufacturing process of quartz-pellets and shows their potential use as thermoluminescence dosimeters (TLD) for those applications where low-levels of ionising radiation are present. Two batches of cold-pressed pellets were produced and their resistance were evaluated by vibration tests and weight-loss measurements. The batch manufactured with 75 Multiplication-Sign 150 Micro-Sign m particles showed enough resistance to be employed as TLD. The dosimetric properties of the 310 Degree-Sign C peak appearing in the glow curves of these pellets were characterized together with commercial TLD-100 units using {gamma}- and X-ray beams with different energies. The uncertainties related to reproducibility and stability of the TL signal were better than 10%. The sensitivity and the linearity of the TL response of quartz-pellets were better than that measured for TLD-100 for doses ranging from 0.5 to 200mGy. The energy dependence of the quartz-pellets was higher than that of TLD-100 but it cannot be considered a restriction to their use in clinical procedures and industrial applications. (author)

  14. Plasma cleaning techniques and future applications in environmentally conscious manufacturing

    Energy Technology Data Exchange (ETDEWEB)

    Ward, P.P.

    1995-07-01

    Plasmas have frequently been used in industry as a last step surface preparation technique in an otherwise predominantly wet-etch process. The limiting factor in the usefulness of plasma cleaning techniques has been the rate at which organic materials are removed. Recent research in the field of plasma chemistry has provided some understanding of plasma processes. By controlling plasma conditions and gas mixtures, ultra-fast plasma cleaning and etching is possible. With enhanced organic removal rates, plasma processes become more desirable as an environmentally sound alternative to traditional solvent or acid dominated process, not only as a cleaning tool, but also as a patterning and machining tool. In this paper, innovations in plasma processes are discussed including enhanced plasma etch rates via plasma environment control and aggressive gas mixtures. Applications that have not been possible with the limited usefulness of past plasma processes are now approaching the realm of possibility. Some of these possible applications will be discussed along with their impact to environmentally conscious manufacturing.

  15. Film forming microbial biopolymers for commercial applications--a review.

    Science.gov (United States)

    Vijayendra, S V N; Shamala, T R

    2014-12-01

    Microorganisms synthesize intracellular, structural and extracellular polymers also referred to as biopolymers for their function and survival. These biopolymers play specific roles as energy reserve materials, protective agents, aid in cell functioning, the establishment of symbiosis, osmotic adaptation and support the microbial genera to function, adapt, multiply and survive efficiently under changing environmental conditions. Viscosifying, gelling and film forming properties of these have been exploited for specific significant applications in food and allied industries. Intensive research activities and recent achievements in relevant and important research fields of global interest regarding film forming microbial biopolymers is the subject of this review. Microbial polymers such as pullulan, kefiran, bacterial cellulose (BC), gellan and levan are placed under the category of exopolysaccharides (EPS) and have several other functional properties including film formation, which can be used for various applications in food and allied industries. In addition to EPS, innumerable bacterial genera are found to synthesis carbon energy reserves in their cells known as polyhydroxyalkanoates (PHAs), microbial polyesters, which can be extruded into films with excellent moisture and oxygen barrier properties. Blow moldable biopolymers like PHA along with polylactic acid (PLA) synthesized chemically in vitro using lactic acid (LA), which is produced by LA bacteria through fermentation, are projected as biodegradable polymers of the future for packaging applications. Designing and creating of new property based on requirements through controlled synthesis can lead to improvement in properties of existing polysaccharides and create novel biopolymers of great commercial interest and value for wider applications. Incorporation of antimicrobials such as bacteriocins or silver and copper nanoparticles can enhance the functionality of polymer films especially in food packaging

  16. Non-manufacturing applications of robotics; Applications non-manufacturieres de la robotique

    Energy Technology Data Exchange (ETDEWEB)

    Dauchez, P. [LIRMM, Laboratoire d' Informatique, de Robotique et de Microelectronique de Montpellier, 34 (France)

    2000-12-01

    This book presents the different non-manufacturing sectors of activity where robotics can have useful or necessary applications: underwater robotics, agriculture robotics, road work robotics, nuclear robotics, medical-surgery robotics, aids to disabled people, entertainment robotics. Service robotics has been voluntarily excluded because this developing sector is not mature yet. (J.S.)

  17. Technology requirements for commercial applications of inertial confinement fusion

    International Nuclear Information System (INIS)

    Frank, T.G.; Rossi, C.E.

    1981-01-01

    Current inertial confinement fusion (ICF) research is directed primarily at physics experiments intended to provide confidence in the scientific feasibility of the basic concept. In conjunction with these experiments, a variety of laser and particle beam drivers having potential for eventual use in fusion power plants is being developed. Expectations are that the scientific feasibility of ICF will be demonstrated in the latter part of the 1980s. At that time, the emphasis of the program will shift to engineering, economic, environmental, and licensing issues with the necessary technology development effort continuing into the early part of the next century. This paper discusses the technology requirements for the successive phases of engineering development leading to commercial application of ICF. The engineering areas requiring significant effort for ICF application include high average power driver development; pulsed high-energy power supply development; reactor cavity and heat transport system design; tritium extraction and control; commercial pellet development; pellet injection, tracking, and targeting systems design; materials radiation, fatigue, and corrosion behavior; and reactor plant systems integration and demonstration

  18. Deploying a Route Optimization EFB Application for Commercial Airline Operational Trials

    Science.gov (United States)

    Roscoe, David A.; Vivona, Robert A.; Woods, Sharon E.; Karr, David A.; Wing, David J.

    2016-01-01

    The Traffic Aware Planner (TAP), developed for NASA Langley Research Center to support the Traffic Aware Strategic Aircrew Requests (TASAR) project, is a flight-efficiency software application developed for an Electronic Flight Bag (EFB). Tested in two flight trials and planned for operational testing by two commercial airlines, TAP is a real-time trajectory optimization application that leverages connectivity with onboard avionics and broadband Internet sources to compute and recommend route modifications to flight crews to improve fuel and time performance. The application utilizes a wide range of data, including Automatic Dependent Surveillance Broadcast (ADS-B) traffic, Flight Management System (FMS) guidance and intent, on-board sensors, published winds and weather, and Special Use Airspace (SUA) schedules. This paper discusses the challenges of developing and deploying TAP to various EFB platforms, our solutions to some of these challenges, and lessons learned, to assist commercial software developers and hardware manufacturers in their efforts to implement and extend TAP functionality in their environments. EFB applications (such as TAP) typically access avionics data via an ARINC 834 Simple Text Avionics Protocol (STAP) server hosted by an Aircraft Interface Device (AID) or other installed hardware. While the protocol is standardized, the data sources, content, and transmission rates can vary from aircraft to aircraft. Additionally, the method of communicating with the AID may vary depending on EFB hardware and/or the availability of onboard networking services, such as Ethernet, WIFI, Bluetooth, or other mechanisms. EFBs with portable and installed components can be implemented using a variety of operating systems, and cockpits are increasingly incorporating tablet-based technologies, further expanding the number of platforms the application may need to support. Supporting multiple EFB platforms, AIDs, avionics datasets, and user interfaces presents a

  19. PERSPECTIVES OF NANOPOWDERS APPLICATION FOR MANUFACTURING OF MODIFYING ALLOYING COMPOSITIONS

    Directory of Open Access Journals (Sweden)

    A. Kalinichenko

    2015-01-01

    Full Text Available Application of nanomaterials for grain refining of metals and its allac is of great interest as it aimis achieveto higher physicalmechanical properties in finished parts. Analysis shows that to gain high effectiveness of nanoparticles it is important to provide proper input of these particles into alloying alloy. The aim of present research is study of initial nanoparticles structure on the base of titanium, boron, yttrium and carbon nanotubes as well as development of method to manufacture alloying alloys containing nanoparticles.Investigations of nanopowders phase compositions on the base of titanium, boron and yttrium have shown that active elements such as boron carbide, titanium carbide and nitride, yttrium oxide are base compounds of these nanopowders. Powder particles are formed by primary structural elements having mainly plate state (titanium and boron carbides and containing equiaxial inclusions with sizes of 5–200 nm. Chemical composition of specimens synthesized is uniform and contains 98.0 – 99.5% of main compound.Results of metal-protector and nanoparticles mixing have revealed that the increase of mixing duration from 2 to 6 hours assist to more uniform elements distribution through the pellet volume. Applying extrusion method specimens of alloying alloys have been produced and elements distribution in cross-section and longitudinal directions were determined.Analysis of research implemented has shown that distribution of active nanopowders in matrix is more uniform in extruded alloying alloys specimens compared to ones produced by methods of sintering or pressing of powder mixtures.

  20. The Enterprise Derivative Application: Flexible Software for Optimizing Manufacturing Processes

    Energy Technology Data Exchange (ETDEWEB)

    Ward, Richard C [ORNL; Allgood, Glenn O [ORNL; Knox, John R [ORNL

    2008-11-01

    The Enterprise Derivative Application (EDA) implements the enterprise-derivative analysis for optimization of an industrial process (Allgood and Manges, 2001). It is a tool to help industry planners choose the most productive way of manufacturing their products while minimizing their cost. Developed in MS Access, the application allows users to input initial data ranging from raw material to variable costs and enables the tracking of specific information as material is passed from one process to another. Energy-derivative analysis is based on calculation of sensitivity parameters. For the specific application to a steel production process these include: the cost to product sensitivity, the product to energy sensitivity, the energy to efficiency sensitivity, and the efficiency to cost sensitivity. Using the EDA, for all processes the user can display a particular sensitivity or all sensitivities can be compared for all processes. Although energy-derivative analysis was originally designed for use by the steel industry, it is flexible enough to be applied to many other industrial processes. Examples of processes where energy-derivative analysis would prove useful are wireless monitoring of processes in the petroleum cracking industry and wireless monitoring of motor failure for determining the optimum time to replace motor parts. One advantage of the MS Access-based application is its flexibility in defining the process flow and establishing the relationships between parent and child process and products resulting from a process. Due to the general design of the program, a process can be anything that occurs over time with resulting output (products). So the application can be easily modified to many different industrial and organizational environments. Another advantage is the flexibility of defining sensitivity parameters. Sensitivities can be determined between all possible variables in the process flow as a function of time. Thus the dynamic development of the

  1. 24 CFR 982.620 - Manufactured home: Applicability of requirements.

    Science.gov (United States)

    2010-04-01

    ... URBAN DEVELOPMENT SECTION 8 TENANT BASED ASSISTANCE: HOUSING CHOICE VOUCHER PROGRAM Special Housing... resident of manufactured home. (1) A family may reside in a manufactured home with assistance under the...-in aide. (1) If approved by the PHA, a live-in aide may reside with the family to care for a person...

  2. Clinical application of domestica manufactured BHP6601 SPECT

    International Nuclear Information System (INIS)

    Zhang Shuwen; Tian Jiahe; Liu Zilai; He Yijie; Shao Mingzhe; Zhang Jinming

    2005-01-01

    Clinical imaging of 150 patients with varying demand is carried out with BHP6601 SPECT manufactured locally, and the results are compared with that obtained by an E. CAM system manufactured by Siemens. The results show that BHP6601 had an acceptable and stable performance from a technical point of view. It offers a sufficient ability for organ imaging of clinical requirement. (authors)

  3. 75 FR 64744 - Manufacturer of Controlled Substances; Notice of Application

    Science.gov (United States)

    2010-10-20

    ... manufacturer of the basic classes of controlled substances listed in schedule I: Drug Schedule Marihuana (7360) I Tetrahydrocannabinols (7370) I The company plans to manufacture small quantities of marihuana derivatives for research purposes. In reference to drug code 7360 (Marihuana), the company plans to bulk...

  4. Application of Nanotechnology in the Manufacturing Sector: A Review

    African Journals Online (AJOL)

    This review of the manufacturing processes in the evolving field of nanotechnology describes the production of nanomaterials by the modification of conventional production techniques. A number of the manufacturing techniques for nanomaterials production and the challenges in the adaptation of the processes to enable ...

  5. Plasma promoted manufacturing of hydrogen and vehicular applications

    Science.gov (United States)

    Bromberg, Leslie

    2003-10-01

    Plasmas can be used for promoting reformation of fuels. Plasma-based reformers developed at MIT use a low temperature, low power, low current electrical discharge to promote partial oxidation conversion of hydrocarbon fuels into hydrogen and CO. The very fuel rich mixture is hard to ignite, and the plasmatron provides a volume-ignition. To minimize erosion and to simplify the power supply, a low current high voltage discharge is used, with wide area electrodes. The plasmatron fuel reformer operates at or slightly above atmospheric pressure. The plasma-based reformer technology provides the advantages of rapid startup and transient response; efficient conversion of the fuel to hydrogen rich gas; compact size; relaxation or elimination of reformer catalyst requirements; and capability to process difficult to reform fuels. These advantages enable use of hydrogen-manufacturing reformation technology in cars using available fuels, such as gasoline and diesel. This plasma-based reformer technology can provide substantial throughputs even without the use of a catalyst. The electrical power consumption of the device is minimized by design and operational characteristics (less than 500 W peak and 200 W average). The product from these plasma reactors is a hydrogen rich mixture that can be used for combustion enhancement and emissions aftertreatment in vehicular applications. By converting a small fraction of the fuel to hydrogen rich gas, in-cylinder combustion can be improved. With minor modification of the engine, use of hydrogen rich gas results in increased fuel efficiency and decreased emissions of smog producing gases. The status of plasma based reformer technology and its application to vehicles will be described.

  6. Applications for Gradient Metal Alloys Fabricated Using Additive Manufacturing

    Science.gov (United States)

    Hofmann, Douglas C.; Borgonia, John Paul C.; Dillon, Robert P.; Suh, Eric J.; Mulder, jerry L.; Gardner, Paul B.

    2013-01-01

    Recently, additive manufacturing (AM) techniques have been developed that may shift the paradigm of traditional metal production by allowing complex net-shaped hardware to be built up layer-by-layer, rather than being machined from a billet. The AM process is ubiquitous with polymers due to their low melting temperatures, fast curing, and controllable viscosity, and 3D printers are widely available as commercial or consumer products. 3D printing with metals is inherently more complicated than with polymers due to their higher melting temperatures and reactivity with air, particularly when heated or molten. The process generally requires a high-power laser or other focused heat source, like an electron beam, for precise melting and deposition. Several promising metal AM techniques have been developed, including laser deposition (also called laser engineered net shaping or LENS® and laser deposition technology (LDT)), direct metal laser sintering (DMLS), and electron beam free-form (EBF). These machines typically use powders or wire feedstock that are melted and deposited using a laser or electron beam. Complex net-shape parts have been widely demonstrated using these (and other) AM techniques and the process appears to be a promising alternative to machining in some cases. Rather than simply competing with traditional machining for cost and time savings, the true advantage of AM involves the fabrication of hardware that cannot be produced using other techniques. This could include parts with "blind" features (like foams or trusses), parts that are difficult to machine conventionally, or parts made from materials that do not exist in bulk forms. In this work, the inventors identify that several AM techniques can be used to develop metal parts that change composition from one location in the part to another, allowing for complete control over the mechanical or physical properties. This changes the paradigm for conventional metal fabrication, which relies on an

  7. Manufacture of functional surfaces through combined application of tool manufacturing processes and Robot Assisted Polishing

    DEFF Research Database (Denmark)

    Eriksen, Rasmus Solmer; Arentoft, Mogens; Grønbæk, J.

    2012-01-01

    The tool surface topography is often a key parameter in the tribological performance of modern metal forming tools. A new generation of multifunctional surfaces is achieved by combination of conventional tool manufacturing processes with a novel Robot Assisted Polishing process. This novel surface...

  8. 40 CFR 417.10 - Applicability; description of the soap manufacturing by batch kettle subcategory.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 28 2010-07-01 2010-07-01 true Applicability; description of the soap... PROTECTION AGENCY (CONTINUED) EFFLUENT GUIDELINES AND STANDARDS SOAP AND DETERGENT MANUFACTURING POINT SOURCE CATEGORY Soap Manufacturing by Batch Kettle Subcategory § 417.10 Applicability; description of the soap...

  9. 40 CFR 417.30 - Applicability; description of the soap manufacturing by fatty acid neutralization subcategory.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 28 2010-07-01 2010-07-01 true Applicability; description of the soap... ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) EFFLUENT GUIDELINES AND STANDARDS SOAP AND DETERGENT MANUFACTURING POINT SOURCE CATEGORY Soap Manufacturing by Fatty Acid Neutralization Subcategory § 417.30 Applicability...

  10. SiGe BiCMOS manufacturing platform for mmWave applications

    Science.gov (United States)

    Kar-Roy, Arjun; Howard, David; Preisler, Edward; Racanelli, Marco; Chaudhry, Samir; Blaschke, Volker

    2010-10-01

    TowerJazz offers high volume manufacturable commercial SiGe BiCMOS technology platforms to address the mmWave market. In this paper, first, the SiGe BiCMOS process technology platforms such as SBC18 and SBC13 are described. These manufacturing platforms integrate 200 GHz fT/fMAX SiGe NPN with deep trench isolation into 0.18μm and 0.13μm node CMOS processes along with high density 5.6fF/μm2 stacked MIM capacitors, high value polysilicon resistors, high-Q metal resistors, lateral PNP transistors, and triple well isolation using deep n-well for mixed-signal integration, and, multiple varactors and compact high-Q inductors for RF needs. Second, design enablement tools that maximize performance and lowers costs and time to market such as scalable PSP and HICUM models, statistical and Xsigma models, reliability modeling tools, process control model tools, inductor toolbox and transmission line models are described. Finally, demonstrations in silicon for mmWave applications in the areas of optical networking, mobile broadband, phased array radar, collision avoidance radar and W-band imaging are listed.

  11. Fabrication of Thermoelectric Devices Using Additive-Subtractive Manufacturing Techniques: Application to Waste-Heat Energy Harvesting

    Science.gov (United States)

    Tewolde, Mahder

    Thermoelectric generators (TEGs) are solid-state devices that convert heat directly into electricity. They are well suited for waste-heat energy harvesting applications as opposed to primary energy generation. Commercially available thermoelectric modules are flat, inflexible and have limited sizes available. State-of-art manufacturing of TEG devices relies on assembling prefabricated parts with soldering, epoxy bonding, and mechanical clamping. Furthermore, efforts to incorporate them onto curved surfaces such as exhaust pipes, pump housings, steam lines, mixing containers, reaction chambers, etc. require custom-built heat exchangers. This is costly and labor-intensive, in addition to presenting challenges in terms of space, thermal coupling, added weight and long-term reliability. Additive manufacturing technologies are beginning to address many of these issues by reducing part count in complex designs and the elimination of sub-assembly requirements. This work investigates the feasibility of utilizing such novel manufacturing routes for improving the manufacturing process of thermoelectric devices. Much of the research in thermoelectricity is primarily focused on improving thermoelectric material properties by developing of novel materials or finding ways to improve existing ones. Secondary to material development is improving the manufacturing process of TEGs to provide significant cost benefits. To improve the device fabrication process, this work explores additive manufacturing technologies to provide an integrated and scalable approach for TE device manufacturing directly onto engineering component surfaces. Additive manufacturing techniques like thermal spray and ink-dispenser printing are developed with the aim of improving the manufacturing process of TEGs. Subtractive manufacturing techniques like laser micromachining are also studied in detail. This includes the laser processing parameters for cutting the thermal spray materials efficiently by

  12. 76 FR 62449 - Manufacturer of Controlled Substances; Notice of Application

    Science.gov (United States)

    2011-10-07

    ...), this is notice that on May 4, 2011, Cambrex Charles City, Inc., 1205 11th Street, Charles City, Iowa... Concentrate of Poppy Straw (9670) II Sufentanil (9740) II Fentanyl (9801) II The company will manufacture the...

  13. 76 FR 66994 - Manufacturer of Controlled Substances; Notice of Application

    Science.gov (United States)

    2011-10-28

    ... following basic classes of controlled substances: Drug Schedule Marihuana (7360) I Cocaine (9041) II The Institute will manufacture marihuana, and cocaine derivatives for use by their customers in analytical kits...

  14. 76 FR 51401 - Manufacturer of Controlled Substances; Notice of Application

    Science.gov (United States)

    2011-08-18

    ... a bulk manufacturer of the following basic classes of controlled substances: Drug Schedule Marihuana... ingredients (APIs) for distribution to its customers. In reference to drug code 7360 (Marihuana), the company...

  15. Additive manufacturing for freeform mechatronics design: from concepts to applications

    NARCIS (Netherlands)

    Baars, G. van; Smeltink, J.; Werff, J. van der; Limpens, M.; Barink, M.; Berg, D. van den; Vreugd, J. de; Witvoet, G.; Galaktionov, O.S.

    2015-01-01

    This article presents developments of freeform mechatronics concepts, enabled by industrial Additive Manufacturing (AM), aiming at breakthroughs for precision engineering challenges such as lightweight, advanced thermal control, and integrated design. To assess potential impact in future

  16. Reconfigurable Manufacturing Systems as an Application of Mass Customisation

    DEFF Research Database (Denmark)

    Jørgensen, Steffen; Nielsen, Kjeld; Jørgensen, Kaj Asbjørn

    2011-01-01

    Manufacturing systems are today developed as engineer to order solutions tailored to producing a specific product or a limited product mix. Such dedicated systems are not consistent with market demands for rapid product changes, product variety, and customisation, which require flexibility...... and responsiveness of manufacturing systems. A Reconfigurable Manufacturing System (RMS) is aimed at possess such flexibility and responsiveness and is said to be the manufacturing paradigm of tomorrow. RMS is, though, not yet fully developed. A similarity between RMS and modular product families, known from Mass...... Customisation (MC), is seen and based on this similarity a potential to maturing RMS further by applying MC methods and techniques is identified. Based on literature surveys this paper analyses this potential by diagnosing gabs for RMS to succeed as a MC product. For each gab MC theory holds related methods...

  17. 77 FR 30021 - Agency Information Collection Activities: Application To Use the Automated Commercial Environment...

    Science.gov (United States)

    2012-05-21

    ... Activities: Application To Use the Automated Commercial Environment (ACE) AGENCY: U.S. Customs and Border...: Application to Use the Automated Commercial Environment (ACE). This is a proposed extension of an information... Environment (ACE) is a trade processing system that will eventually replace the Automated Commercial System...

  18. Commercial-grade motors in safety-related applications: Final report

    International Nuclear Information System (INIS)

    Holzman, P.M.

    1988-04-01

    The objective of this project was to discuss the process necessary to utilize commercial grade equipment in safety related applications and to provide utilities with guidance for accepting commercial grade motors for safety-related applications. The generic commercial-grade concepts presented in this report can be successfully applied to motors. Commercial grade item utilization has the greatest applicability to motors in ''mild'' environments, because these motors are essentially similar to commercial grade motors in materials, construction methods, and capabilities. The acceptance process is less applicable to motors that are subject to ''harsh'' environments during postulated accidents, because of the unique design features and testing required to qualify these motors

  19. Generic requirements specification for qualifying a commercially available PLC for safety-related applications in nuclear power plants. Final report

    International Nuclear Information System (INIS)

    Ostenso, A.; May, R.

    1996-12-01

    This is a specification for qualifying a commercially available PLC for application to safety systems in nuclear power plants. The specifications are suitable for evaluating a particular PLC product line as a platform for safety-related applications, establishing a suitable qualification test program, and confirming that the manufacturer has a quality assurance program that is adequate for safety-related applications or is sufficiently complete that, with a reasonable set of compensatory actions, it can be brought into conformance. The specification includes requirements for: (1) quality assurance measures applied to the qualification activities, (2) documentation to support the qualification, and (3) documentation to provide the information needed for applying the qualified PLC platform to a specific application. The specifications are designed to encompass a broad range of safety applications; however, qualifying a particular platform for a different range of applications can be accomplished by appropriate adjustments to the requirements

  20. Personalized skincare: from molecular basis to clinical and commercial applications

    Directory of Open Access Journals (Sweden)

    Markiewicz E

    2018-04-01

    Full Text Available Ewa Markiewicz, Olusola Clement Idowu Research & Development, Hexis Lab, Science Central, The Core, Bath Lane, Newcastle upon Tyne, UK Abstract: Individual responses of human skin to the environmental stress are determined by differences in the anatomy and physiology that are closely linked to the genetic characteristics such as pigmentation. Ethnic skin phenotypes can be distinguished based on defined genotypic traits, structural organization and compartmentalized sensitivity to distinct extrinsic aging factors. These differences are not only responsible for the variation in skin performance after exposure to damaging conditions, but can also affect the mechanisms of drug absorption, sensitization and other longer term effects. The unique characteristics of the individual skin function and, particularly, of the ethnic skin type are currently considered to shape the future of clinical and pharmacologic interventions as a basis for personalized skincare. Individual approaches to skincare render a novel and actively growing area with a range of biomedical and commercial applications within cosmetics industry. In this review, we summarize the aspects of the molecular and clinical manifestations of the environmental stress on human skin and proposed protective mechanisms that are linked to ethnic differences and pathophysiology of extrinsic skin aging. We subsequently discuss the possible applications and translation of this knowledge into personalized skincare. Keywords: pigmentation, gene polymorphism, photodamage, environmental stress, cosmetics

  1. Numerical Modeling and Design of Thermoelectric Cooling Systems and Its Application to Manufacturing Machines

    Science.gov (United States)

    Gallo, A.; Arana, A.; Oyanguren, A.; García, G.; Barbero, A.; Larrañaga, J.; Ulacia, I.

    2013-07-01

    In this work the properties of thermoelectric modules (TEMs) and their behavior have been numerically modeled. Moreover, their applications very often require modeling not only of the TEM but also of the working environment and the product in which they will be working. A clear example is the fact that TEMs are very often installed with heat-dissipating elements such as fans, heat sinks, and heat exchangers; thus, the module will only work according to the heat dissipation conditions that these external sources can provide in a certain environment. In this context, analytic approaches, even though they have been proved to be useful, do not provide enough, accurate information in this regard. Therefore, numerical modeling has been identified as a powerful tool to improve detailed designs of thermoelectric solutions. This paper presents numerical simulations of a TEM in different working conditions, as well as with different commercial dissipation devices. The objective is to obtain the characteristic curve of a TEM using a valid numerical model that can be introduced into larger models of different applications. Also, the numerical model of the module and different cooling devices is provided. Both of them are compared against real tested modules, so that the deviation between them can be measured and discussed. Finally, the TEM is introduced into a manufacturing application and results are discussed to validate the model for further use.

  2. Commercial Clinical Application of Boron Neutron Capture Therapy

    International Nuclear Information System (INIS)

    1999-01-01

    CRADA No. 95-CR-09 among the LITCO--now Bechtel BWXT Idaho, LLC; a private company, Neutron Therapies Limited Liability Company, NTL formerly Ionix Corporation; and Washington State University was established in 1996 to further the development of BNCT. NTL has established a laboratory for the synthesis, under US FDA approved current Good Manufacturing Practices (cGMP) guidelines, of key boron intermediates and final boron agents for BNCT. The company has focused initially on the development of the compound GB-10 (Na 2 B 10 H 10 ) as the first boron agent of interest. An Investigational New Drug (IND) application for GB-10 has been filed and approved by the FDA for a Phase I human biodistribution trial in patients with non-small cell lung cancer and glioblastoma multiforme at UW under the direction of Professor Keith Stelzer, Principal Investigator (PI). These trials are funded by NTL under a contract with the UW, Department of Radiation Oncology, and the initial phases are nearing completion. Initial results show that boron-10 concentrations on the order of 100 micrograms per gram (100 ppm) can be achieved and maintained in blood with no indication of toxicity

  3. Study on the Transformation and Upgrade of E-Commerce Application in Manufacturing Industry

    Directory of Open Access Journals (Sweden)

    Zhao Liang

    2017-01-01

    Full Text Available Under the Internet thinking, manufacturing management mode is changed, it is not depend on the scale, but in the user as the center, more dependent on the reaction rate of user requirements. As the big data, cloud computing, Internet of things technology such as the development of technology, manufacturing is from automatic to intelligent evolution, on the user's personalized customization is possible. Using Internet thinking positive development manufacturing enterprise electronic commerce application mode of transformation and upgrading of manufacturing industry plays an important role. Promoting the continued ascent of manufacturing industry informatization level, promote the transformation of the manufacturing production mode, provide greater profit space for the export of products. In industrial 4.0 mode, the user is the core of the enterprise, C2B model will be the mainstream of future manufacturing e-commerce application mode. This paper to present the sorted out the basic model of manufacturing enterprise electronic commerce application, point out the existing problems, and the computing technology, communication technology, the constant development of storage technology, such as background, puts forward the corresponding countermeasure, points out that the C2B model is the development direction of manufacturing enterprise electronic commerce application mode.

  4. Computers for Manned Space Applications Base on Commercial Off-the-Shelf Components

    Science.gov (United States)

    Vogel, T.; Gronowski, M.

    2009-05-01

    Similar to the consumer markets there has been an ever increasing demand in processing power, signal processing capabilities and memory space also for computers used for science data processing in space. An important driver of this development have been the payload developers for the International Space Station, requesting high-speed data acquisition and fast control loops in increasingly complex systems. Current experiments now even perform video processing and compression with their payload controllers. Nowadays the requirements for a space qualified computer are often far beyond the capabilities of, for example, the classic SPARC architecture that is found in ERC32 or LEON CPUs. An increase in performance usually demands costly and power consuming application specific solutions. Continuous developments over the last few years have now led to an alternative approach that is based on complete electronics modules manufactured for commercial and industrial customers. Computer modules used in industrial environments with a high demand for reliability under harsh environmental conditions like chemical reactors, electrical power plants or on manufacturing lines are entered into a selection procedure. Promising candidates then undergo a detailed characterisation process developed by Astrium Space Transportation. After thorough analysis and some modifications, these modules can replace fully qualified custom built electronics in specific, although not safety critical applications in manned space. This paper focuses on the benefits of COTS1 based electronics modules and the necessary analyses and modifications for their utilisation in manned space applications on the ISS. Some considerations regarding overall systems architecture will also be included. Furthermore this paper will also pinpoint issues that render such modules unsuitable for specific tasks, and justify the reasons. Finally, the conclusion of this paper will advocate the implementation of COTS based

  5. Application of green concept in mechanical design and manufacture

    Science.gov (United States)

    Liu, Xing ping

    2017-11-01

    With the development of productive forces, the relationship between human and nature is becoming tight increasingly, especially environmental pollution and resource consumption that comes from equipment manufacturing industry mainly. Green development concept is a new concept which can solve the current ecological environment. The philosophical foundation and theoretical basis of green idea are expounded through the study of scientific development and green concept. The difference between the traditional design and the green design is analyzed; the meaning and content of the mechanical design for green concept are discussed. And the evaluation method of green design is discussed too. The significance of green development concept in the mechanical design and manufacturing science is pinpointed clearly. The results show that the implementation of green design under the mechanical design, from the source of pollution control to achieve green manufacturing, is the only way to achieve sustainable development.

  6. Non-commercial vs. commercial clinical trials: a retrospective study of the applications submitted to a research ethics committee.

    Science.gov (United States)

    Fuentes Camps, Inmaculada; Rodríguez, Alexis; Agustí, Antonia

    2018-02-15

    There are many difficulties in undertaking independent clinical research without support from the pharmaceutical industry. In this retrospective observational study, some design characteristics, the clinical trial public register and the publication rate of noncommercial clinical trials were compared to those of commercial clinical trials. A total of 809 applications of drug-evaluation clinical trials were submitted from May 2004 to May 2009 to the research ethics committee of a tertiary hospital, and 16.3% of trials were noncommercial. They were mainly phase IV, multicentre national, and unmasked controlled trials, compared to the commercial trials that were mainly phase II or III, multicentre international, and double-blind masked trials. The commercial trials were registered and published more often than noncommercial trials. More funding for noncommercial research is still needed. The results of the research, commercial or noncommercial, should be disseminated in order not to compromise either its scientific or its social value. © 2018 The British Pharmacological Society.

  7. Technology and Manufacturing Readiness of Early Market Motive and Non-Motive Hydrogen Storage Technologies for Fuel Cell Applications

    Energy Technology Data Exchange (ETDEWEB)

    Ronnebro, Ewa

    2012-06-16

    PNNL’s objective in this report is to provide DOE with a technology and manufacturing readiness assessment to identify hydrogen storage technologies’ maturity levels for early market motive and non-motive applications and to provide a path forward toward commercialization. PNNL’s Technology Readiness Assessment (TRA) is based on a combination of Technology Readiness Level (TRL) and Manufacturing Readiness Level (MRL) designations that enable evaluation of hydrogen storage technologies in varying levels of development. This approach provides a logical methodology and roadmap to enable the identification of hydrogen storage technologies, their advantages/disadvantages, gaps and R&D needs on an unbiased and transparent scale that is easily communicated to interagency partners. The TRA report documents the process used to conduct the TRA, reports the TRL and MRL for each assessed technology and provides recommendations based on the findings.

  8. 76 FR 77257 - Manufacturer of Controlled Substances; Notice of Application

    Science.gov (United States)

    2011-12-12

    ...), this is notice that on September 15, 2011, Johnson Matthey Pharma Services, 70 Flagship Drive, North... Schedule Amphetamine (1100) II Methylphenidate (1724) II Hydrocodone (9193) II The company plans to utilize... conduct analytical testing in support of the company's primary manufacturing facility in West Deptford...

  9. 76 FR 25376 - Manufacturer of Controlled Substances; Notice of Application

    Science.gov (United States)

    2011-05-04

    ...), this is notice that on January 5, 2011, Johnson Matthey Pharma Services, 70 Flagship Drive, North... Schedule Amphetamine (1100) II Methylphenidate (1724) II Hydrocodone (9193) II The company plans to utilize... conduct analytical testing in support of the company's primary manufacturing facility in West Deptford...

  10. 76 FR 72974 - Manufacturer of Controlled Substances Notice of Application

    Science.gov (United States)

    2011-11-28

    ... is notice that on September 15, 2011, Johnson Matthey Pharmaceutical Materials Inc., Pharmaceutical... (9193) II Alfentanil (9737) II Remifentanil (9739) II Sufentanil (9740) II The company plans to utilize... conduct analytical testing in support of the company's primary manufacturing facility in West Deptford...

  11. 75 FR 47029 - Manufacturer of Controlled Substances; Notice of Application

    Science.gov (United States)

    2010-08-04

    ...), this is notice that on January 27, 2009, Johnson Matthey Pharma Services, 70 Flagship Drive, North... Schedule Amphetamine (1100) II Hydrocodone (9193) II Methylphenidate (1724) II The company plans to utilize... conduct analytical testing in support of the company's primary manufacturing facility in West Deptford...

  12. Biomedical applications of additive manufacturing: present and future

    NARCIS (Netherlands)

    Singh, Sunpreet; Ramakrishna, Seeram; Bouten, Carlijn V.C.; Narayan, Roger

    2017-01-01

    Three dimensional printing (3DP) or additive manufacturing (AM) of medical devices and scaffolds for tissue engineering, regenerative medicine, ex-vivo tissues and drug delivery is of intense interest in recent years. A few medical devices namely, ZipDose ® , Pharmacoprinting, powder bed fusion,

  13. Apparatus for manufacturing ceramics microspheres for cementing applications

    NARCIS (Netherlands)

    2012-01-01

    A method and apparatus for manufacturing ceramic microspheres from industrial slag. The micro spheres have a particle size of about 38 microns to about 150 microns. The microspheres are used to create a cement slurry having a density of at least about Illbs/g. The resultant cement slurry may then be

  14. Application of additive manufacturing in oral and maxillofacial surgery

    NARCIS (Netherlands)

    Farré-Guasch, E.; Wolff, J.; Helder, M.N.; Schulten, E.A.J.M.; Forouzanfar, T.; Klein-Nulend, J.

    2015-01-01

    Additive manufacturing is the process of joining materials to create objects from digital 3-dimensional (3D) model data,which is a promising technology in oral andmaxillofacial surgery. The management of lost craniofacial tissues owing to congenital abnormalities, trauma, or cancer treatment poses a

  15. Microstructure and texture evolution in aluminum and commercially pure titanium dissimilar welds fabricated using ultrasonic additive manufacturing

    International Nuclear Information System (INIS)

    Sridharan, Niyanth; Wolcott, Paul; Dapino, Marcelo; Babu, S.S.

    2016-01-01

    Ultrasonic additive manufacturing (UAM) is a solid-state hybrid manufacturing technique. In this work characterization using electron back scatter diffraction was performed on aluminum–titanium dissimilar metal welds made using a 9 kW ultrasonic additive manufacturing system. The results showed that the aluminum texture at the interface after ultrasonic additive manufacturing is similar to aluminum texture observed during accumulative roll bonding of aluminum alloys. It is finally concluded that the underlying mechanism of bond formation in ultrasonic additive manufacturing primarily relies on severe shear deformation at the interface.

  16. Challenges and opportunities of fibre-reinforced polymers in additive manufacturing with focus on industrial applications

    DEFF Research Database (Denmark)

    Hofstätter, Thomas; Pedersen, David Bue; Tosello, Guido

    2017-01-01

    Functional parts made by additive manufacturing of polymers have entered the area of industrial applications in recent years providing a wide range of materials with various mechanical, thermal, and electrical properties. These additive manufacturing processes can be combined with known fibre...

  17. The application of Quick Response Manufacturing practices in Brazil, Europe, and the USA : An exploratory study

    NARCIS (Netherlands)

    Godinho Filho, Moacir; Marchesini, Antonio Gilberto; Riezebos, Jan; Vandaele, Nico; Devos Ganga, Gilberto Miller

    2017-01-01

    This research investigates the application of Quick Response Manufacturing (QRM) practices by enterprises in Brazil, Europe, and the USA. QRM is a management concept that focuses on time as the key factor in competitive manufacturing, particularly in customer-oriented Engineer and Make to Order

  18. 77 FR 20356 - Foreign-Trade Zone 277-Western Maricopa County, AZ; Application for Manufacturing Authority...

    Science.gov (United States)

    2012-04-04

    ... Maricopa County, AZ; Application for Manufacturing Authority; Suntech Arizona, Inc., (Solar Panel... facility is used for the manufacture of 275 and 290 watt solar panels for industrial use. Components and... to solar panels (duty-free) for the foreign inputs noted above. Suntech would also be exempt from...

  19. 40 CFR 417.150 - Applicability; description of the manufacture of spray dried detergents subcategory.

    Science.gov (United States)

    2010-07-01

    ... detergents, including but not limited to assembly and storage of raw materials, crutching, spray drying... manufacture of spray dried detergents subcategory. 417.150 Section 417.150 Protection of Environment... POINT SOURCE CATEGORY Manufacture of Spray Dried Detergents Subcategory § 417.150 Applicability...

  20. Industrial and commercial applications for a Triga reactor

    International Nuclear Information System (INIS)

    Green, D.

    1986-01-01

    The Physics and Radioisotope Services Group of ICI operates a Triga Reactor in support of a commercial, Industrial Radioisotope Technology Service. The technical and commercial development of this business is discussed in the context of operating a Triga Reactor in an Industrial Environment. (author)

  1. Magnetic giant magnetoresistance commercial off the shelf for space applications

    DEFF Research Database (Denmark)

    Michelena, M.D.; Oelschlägel, Wulf; Arruego, I.

    2008-01-01

    The increase of complexity and miniaturizing level of Aerospace platforms make use of commercial off the shelf (COTS) components constitute a plausible alternative to the use of military or rad-tolerant components. In this work, giant magnetoresistance commercial sensors are studied to be used as......-375 mu T biasing field. (c) 2008 American Institute of Physics....

  2. Commercial-Industrial Cleaning, by Pressure-Washing, Hydro-Blasting and UHP-Jetting The Business Operating Model and How-To Manual for 450 Specific Applications

    CERN Document Server

    Maasberg, Wolfgang

    2012-01-01

    Commercial-Industrial Cleaning, by Pressure-Washing, Hydro-Blasting and UHP-Jetting is the first proprietary manual for cleaning and rehabilitation through pressure-washing, hydro-blasting and ultra high pressure water jetting (UHP).   It examines the cleaning, restoration and rehabilitation of statuary and historical structures; manufacturing hardware; and application technologies for residential, commercial and industrial areas, structures and buildings. Commercial-Industrial Cleaning, by Pressure-Washing, Hydro-Blasting and UHP-Jetting contains over 450 applications from agricultural, marine, municipal, food processing, paper-pulp, pharmaceutical and cosmetic, industrial and power generating maintenance areas. It includes gear lists to help readers easily identify the appropriate tooling and equipment for each specific application and industry.   Commercial-Industrial Cleaning, by Pressure-Washing, Hydro-Blasting and UHP-Jetting supplies readers with the tools to create a successful business model for re...

  3. 77 FR 14535 - Agency Information Collection Activities: Application To Use the Automated Commercial Environment...

    Science.gov (United States)

    2012-03-12

    ... Activities: Application To Use the Automated Commercial Environment (ACE) AGENCY: U.S. Customs and Border... Commercial Environment (ACE). This request for comment is being made pursuant to the Paperwork Reduction Act... Number: None. Abstract: The Automated Commercial Environment (ACE) is a trade processing system that will...

  4. Additive manufacturing: Characterization of TI-6AI-4V alloy intended for biomedical application

    CSIR Research Space (South Africa)

    Ramosoeu, ME

    2010-10-01

    Full Text Available Direct Metal Laser Sintering (DMLS) is one of the new Laser Additive Manufacturing (LAM) techniques used for producing complex topology components mostly found in medical applications. The work presented in this paper focuses on metallographic...

  5. 78 FR 19017 - Manufacturer of Controlled Substances; Notice of Application; Johnson Matthey Pharmaceutical...

    Science.gov (United States)

    2013-03-28

    ... DEPARTMENT OF JUSTICE Drug Enforcement Administration Manufacturer of Controlled Substances; Notice of Application; Johnson Matthey Pharmaceutical Materials, Inc. Pursuant to Sec. 1301.33(a), Title... Matthey Pharmaceutical Materials, Inc., Pharmaceutical Service, 25 Patton Road, Devens, Massachusetts...

  6. Tropical Fruit Irradiation-From Research to Commercial Application

    International Nuclear Information System (INIS)

    Moy, James H.

    2005-09-01

    Food irradiation is an emerging technology for the 21st century. Extensive research and development worldwide in the past 40 years have proved the versatility and efficacy. With low, medium to high dose, and using either a gamma, electrons, or x-ray source, radiation can: 1) disinfest plant products and spices; 2) extend shelf life of tubers, bulbs, and selected tropical fruits; 3) decontaminate meats and seafood; 4) sterilize spices and special meals; and 5) improve product utilization. Criteria for testing its efficacy include effectiveness, efficiency, and the ability to retain product quality. The use of irradiation as a quarantine treatment of tropical fruits is potentially attractive to countries growing these fruits. A two-prong research plan should aim at proving radiation's effectiveness in preventing emergence of all insect pests that might be on a fruit, and determining that all quality attributes of a host fruit are retained after irradiation, subsequent storage and shipment. ommercial application involves conducting an economical feasibility study; market research and testing; selection of radiation source and irradiator type; training of personnel for plant operations, radiation safety and dosimetry monitoring; designing of packages and choosing the most cost-effective means of transporting treated fruits to market destinations. When all of hese are achieved, it should lead to a continuous and profitable operation. Researchers at the University of Hawaii using a gamma irradiator from the mid-1960s to early 2000s had amassed a volume of data to prove the efficacy of radiation disinfestations. And installation of a commercial x-ray irradiator in 2000 on the Island of Hawaii has enabled fruit farmers and packers to use this technology for exporting tropical fruits to distant markets

  7. Additive Manufacturing Technologies Used for Processing Polymers: Current Status and Potential Application in Prosthetic Dentistry.

    Science.gov (United States)

    Revilla-León, Marta; Özcan, Mutlu

    2018-04-22

    There are 7 categories of additive manufacturing (AM) technologies, and a wide variety of materials can be used to build a CAD 3D object. The present article reviews the main AM processes for polymers for dental applications: stereolithography (SLA), digital light processing (DLP), material jetting (MJ), and material extrusion (ME). The manufacturing process, accuracy, and precision of these methods will be reviewed, as well as their prosthodontic applications. © 2018 by the American College of Prosthodontists.

  8. Application of text mining for customer evaluations in commercial banking

    Science.gov (United States)

    Tan, Jing; Du, Xiaojiang; Hao, Pengpeng; Wang, Yanbo J.

    2015-07-01

    Nowadays customer attrition is increasingly serious in commercial banks. To combat this problem roundly, mining customer evaluation texts is as important as mining customer structured data. In order to extract hidden information from customer evaluations, Textual Feature Selection, Classification and Association Rule Mining are necessary techniques. This paper presents all three techniques by using Chinese Word Segmentation, C5.0 and Apriori, and a set of experiments were run based on a collection of real textual data that includes 823 customer evaluations taken from a Chinese commercial bank. Results, consequent solutions, some advice for the commercial bank are given in this paper.

  9. Commercialization of terrestrial applications of aerospace power technology

    International Nuclear Information System (INIS)

    Landsberg, D.R.

    1992-01-01

    The potential for commercialization of terrestrial energy systems based upon aerospace power technology's explored. Threats to the aerospace power technology industry, caused by the end of the cold war and weak world economy are described. There are also new opportunities caused by increasing terrestrial energy needs and world-wide concern for the environment. In this paper, the strengths and weaknesses of the aerospace power industry in commercializing terrestrial energy technologies are reviewed. Finally, actions which will enable the aerospace power technology industry to commercialize products into terrestrial energy markets are described

  10. Space Commercialization

    Science.gov (United States)

    Martin, Gary L.

    2011-01-01

    A robust and competitive commercial space sector is vital to continued progress in space. The United States is committed to encouraging and facilitating the growth of a U.S. commercial space sector that supports U.S. needs, is globally competitive, and advances U.S. leadership in the generation of new markets and innovation-driven entrepreneurship. Energize competitive domestic industries to participate in global markets and advance the development of: satellite manufacturing; satellite-based services; space launch; terrestrial applications; and increased entrepreneurship. Purchase and use commercial space capabilities and services to the maximum practical extent Actively explore the use of inventive, nontraditional arrangements for acquiring commercial space goods and services to meet United States Government requirements, including measures such as public-private partnerships, . Refrain from conducting United States Government space activities that preclude, discourage, or compete with U.S. commercial space activities. Pursue potential opportunities for transferring routine, operational space functions to the commercial space sector where beneficial and cost-effective.

  11. 48 CFR 12.503 - Applicability of certain laws to Executive agency contracts for the acquisition of commercial items.

    Science.gov (United States)

    2010-10-01

    ... laws to Executive agency contracts for the acquisition of commercial items. 12.503 Section 12.503... COMMERCIAL ITEMS Applicability of Certain Laws to the Acquisition of Commercial Items and Commercially... acquisition of commercial items. (a) The following laws are not applicable to Executive agency contracts for...

  12. Prediction of Bending Stiffness for Laminated CFRP and Its Application to Manufacturing of Roof Reinforcement

    Directory of Open Access Journals (Sweden)

    Jeong-Min Lee

    2014-05-01

    Full Text Available Recently, carbon fiber reinforced plastic (CFRP with high strength, stiffness, and lightweight is used widely in number of composite applications such as commercial aircraft, transportation, machinery, and sports equipment. Especially, it is necessary to apply lightweight materials to car components for reducing energy consumption and CO2 emissions. In case of car roof reinforcement manufactured using CFRP, superior strength and bending stiffness are required for the safety of drivers in the rollover accident. Mechanical properties of CFRP laminates are generally dependent on the stacking sequence. Therefore, research of stacking sequence using CFRP prepreg is required for superior bending stiffness. In this study, the 3-point bending FE-analysis for predicting the bending stiffness of CFRP roof reinforcement was carried out on three cases [0PW∘]5, [0PW°/0UD°/0-PW°]s, and [0UD∘]5. Material properties that the six independent elastic constants are E11, E22, G12, G23, G13, and ν12 used in FE-analysis were evaluated by the tensile test in 0°, 45°, and 90° directions. Through structural strength analysis of the automobile roof reinforcement fabricated using CFRP, the effect of the stacking sequence on the bending stiffness was evaluated and validated through experiments under the same conditions as the analysis.

  13. Application of Best Industry Practices to the Design of Commercial Refrigerators

    Energy Technology Data Exchange (ETDEWEB)

    None

    2002-06-30

    The substantial efficiency improvements which have been realized in residential refrigerators over the last twenty years due to implementation of the National Appliance Energy Conservation Act and changing consumer reactions to energy savings give an indication of the potential for improvement in the commercial sector, where few such efficiency improvements have been made to date. The purchase decision for commercial refrigerators is still focused primarily on first cost and product performance issues such as maximizing storage capacity, quick pulldown, durability, and reliability. The project applied techniques used extensively to reduce energy use in residential refrigeration to a commercial reach-in refrigerator. The results will also be applicable to other commercial refrigeration equipment, such as refrigerated vending machines, reach-in freezers, beverage merchandisers, etc. The project described in this paper was a collaboration involving the Appliance and Building Technology Sector of TIAX, the Delfield Company, and the U. S. Department of Energy's Office of Building Technologies. Funding was provided by DOE through Cooperative Agreement No. DE-FC26-00NT41000. The program plan and schedule were structured to assure successful integration of the TIAX work on development of efficient design concepts into Delfield's simultaneous development of the Vantage product line. The energy-saving design options evaluated as part of the development included brushless DC and PSC fan motors, high-efficiency compressors, variable-speed compressor technology, cabinet thermal improvement (particularly in the face frame area), increased insulation thickness, a trap for the condensate line, improved insulation, reduced-wattage antisweat heaters, non-electric antisweat heating, off-cycle defrost termination, rifled heat exchanger tubing, and system optimization (selection of heat exchangers, fans, and subcooling, superheat, and suction temperatures for efficient

  14. Laser additive manufacturing of 3D meshes for optical applications.

    Science.gov (United States)

    Essa, Khamis; Sabouri, Aydin; Butt, Haider; Basuny, Fawzia Hamed; Ghazy, Mootaz; El-Sayed, Mahmoud Ahmed

    2018-01-01

    Selective laser melting (SLM) is a widely used additive manufacturing process that can be used for printing of intricate three dimensional (3D) metallic structures. Here we demonstrate the fabrication of titanium alloy Ti-6Al-4V alloy based 3D meshes with nodally-connected diamond like unit cells, with lattice spacing varying from 400 to 1000 microns. A Concept Laser M2 system equipped with laser that has a wavelength of 1075 nm, a constant beam spot size of 50μm and maximum power of 400W was used to manufacture the 3D meshes. These meshes act as optical shutters / directional transmitters and display interesting optical properties. A detailed optical characterisation was carried out and it was found that these structures can be optimised to act as scalable rotational shutters with high efficiencies and as angle selective transmission screens for protection against unwanted and dangerous radiations. The efficiency of fabricated lattice structures can be increased by enlarging the meshing size.

  15. Laser additive manufacturing of 3D meshes for optical applications.

    Directory of Open Access Journals (Sweden)

    Khamis Essa

    Full Text Available Selective laser melting (SLM is a widely used additive manufacturing process that can be used for printing of intricate three dimensional (3D metallic structures. Here we demonstrate the fabrication of titanium alloy Ti-6Al-4V alloy based 3D meshes with nodally-connected diamond like unit cells, with lattice spacing varying from 400 to 1000 microns. A Concept Laser M2 system equipped with laser that has a wavelength of 1075 nm, a constant beam spot size of 50μm and maximum power of 400W was used to manufacture the 3D meshes. These meshes act as optical shutters / directional transmitters and display interesting optical properties. A detailed optical characterisation was carried out and it was found that these structures can be optimised to act as scalable rotational shutters with high efficiencies and as angle selective transmission screens for protection against unwanted and dangerous radiations. The efficiency of fabricated lattice structures can be increased by enlarging the meshing size.

  16. 40 CFR 171.3 - Categorization of commercial applicators of pesticides.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 23 2010-07-01 2010-07-01 false Categorization of commercial applicators of pesticides. 171.3 Section 171.3 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) PESTICIDE PROGRAMS CERTIFICATION OF PESTICIDE APPLICATORS § 171.3 Categorization of commercial...

  17. Application of surface-enhanced Raman spectroscopy (SERS) for cleaning verification in pharmaceutical manufacture.

    Science.gov (United States)

    Corrigan, Damion K; Cauchi, Michael; Piletsky, Sergey; Mccrossen, Sean

    2009-01-01

    Cleaning verification is the process by which pharmaceutical manufacturing equipment is determined as sufficiently clean to allow manufacture to continue. Surface-enhanced Raman spectroscopy (SERS) is a very sensitive spectroscopic technique capable of detection at levels appropriate for cleaning verification. In this paper, commercially available Klarite SERS substrates were employed in order to obtain the necessary enhancement of signal for the identification of chemical species at concentrations of 1 to 10 ng/cm2, which are relevant to cleaning verification. The SERS approach was combined with principal component analysis in the identification of drug compounds recovered from a contaminated steel surface.

  18. Commercial Applications at FRM II Based on Neutron Irradiations

    Energy Technology Data Exchange (ETDEWEB)

    Gerstenberg, H.; Draack, A.; Kastenmuller, A. [Technische Universitaet Muenchen, Munchen (Germany)

    2013-07-01

    Due to its design as a heavy water moderated reactor with a very compact core FRM II, Germany's most modern and most powerful research reactor, offers excellent conditions for basic research using beam tubes. On the other hand it is equipped with various irradiation facilities to be used mainly for industrial purposes. From the very beginning of reactor operation a dedicated department had been implemented in order to provide a neutron irradiation service to interested parties on a commercial basis. As of today the most widely used application is Si doping. The semiautomatic doping facility accepts ingots with diameters between 125 mm and 200 mm and a maximum height of 500 mm. The irradiation channel is located deep in the heavy water tank and exhibits a ratio of thermal/fast neutron flux density of > 1000. This value allows the doping of Si to a target resistivity as high as 1100 Ωcm within the tight limits regarding accuracy and homogeneity specified by the customer. Typically the throughput of Si doped in FRM II sums up to about 15 t/year. Another topic of growing importance is the use of FRM II aiming the production of radioisotopes mainly for the radiopharmaceutical industry. The maybe most challenging example is the production of Lu-177 n. c. a. based on the irradiation of Yb{sub 2}O{sub 3} to a high fluence of thermal neutrons of typically 1.5E20 cm{sup -2}. The Lu-177 activity delivered to the customer is in the range of 750 GBq. With respect to further processing it turned out to be a highly advantageous to have the laboratories of ITG, the company extracting the Lu-177 from the freshly irradiated Yb{sub 2}O{sub 3} on site FRM II. Further irradiation facilities are available at FRM II in order to allow the activation of samples for analytical purposes or to irradiate samples for geochronological investigations using the fission track technique. Finally a project on the future installation of a facility dedicated to the irradiation of U-targets for

  19. Use of advanced commercial ICs (COTS) for space application

    International Nuclear Information System (INIS)

    Strobel, D.J.; Czajkowski, D.R.; Layton, P.; Shanken, S.

    1999-01-01

    A product line of space-qualified radiation-tolerant ICs based on a high-volume commercial-off-the-shelf (COTS) silicon has been developed. The basic results from over 300 lots of COTS silicon, assembled and screened to Class B and Class S requirements will be presented. Intelligent use of commercial ICs engineered to improve radiation performance, is effective in introducing advanced technology to new satellite systems. Space Electronics has introduced over 125 space-qualified microelectronics standard products, that are used on over 90 space projects. (authors)

  20. Process monitoring for intelligent manufacturing processes - Methodology and application to Robot Assisted Polishing

    DEFF Research Database (Denmark)

    Pilny, Lukas

    Process monitoring provides important information on the product, process and manufacturing system during part manufacturing. Such information can be used for process optimization and detection of undesired processing conditions to initiate timely actions for avoidance of defects, thereby improving...... quality assurance. This thesis is aimed at a systematic development of process monitoring solutions, constituting a key element of intelligent manufacturing systems towards zero defect manufacturing. A methodological approach of general applicability is presented in this concern.The approach consists...... of six consecutive steps for identification of product Vital Quality Characteristics (VQCs) and Key Process Variables (KPVs), selection and characterization of sensors, optimization of sensors placement, validation of the monitoring solutions, definition of the reference manufacturing performance...

  1. Analytics for smart energy management tools and applications for sustainable manufacturing

    CERN Document Server

    Oh, Seog-Chan

    2016-01-01

    This book introduces the issues and problems that arise when implementing smart energy management for sustainable manufacturing in the automotive manufacturing industry and the analytical tools and applications to deal with them. It uses a number of illustrative examples to explain energy management in automotive manufacturing, which involves most types of manufacturing technology and various levels of energy consumption. It demonstrates how analytical tools can help improve energy management processes, including forecasting, consumption, and performance analysis, emerging new technology identification as well as investment decisions for establishing smart energy consumption practices. It also details practical energy management systems, making it a valuable resource for professionals involved in real energy management processes, and allowing readers to implement the procedures and applications presented.

  2. Enhancing cell and gene therapy manufacture through the application of advanced fluorescent optical sensors (Review).

    Science.gov (United States)

    Harrison, Richard P; Chauhan, Veeren M

    2017-12-15

    Cell and gene therapies (CGTs) are examples of future therapeutics that can be used to cure or alleviate the symptoms of disease, by repairing damaged tissue or reprogramming defective genetic information. However, despite the recent advancements in clinical trial outcomes, the path to wide-scale adoption of CGTs remains challenging, such that the emergence of a "blockbuster" therapy has so far proved elusive. Manufacturing solutions for these therapies require the application of scalable and replicable cell manufacturing techniques, which differ markedly from the existing pharmaceutical incumbent. Attempts to adopt this pharmaceutical model for CGT manufacture have largely proved unsuccessful. The most significant challenges facing CGT manufacturing are process analytical testing and quality control. These procedures would greatly benefit from improved sensory technologies that allow direct measurement of critical quality attributes, such as pH, oxygen, lactate and glucose. In turn, this would make manufacturing more robust, replicable and standardized. In this review, the present-day state and prospects of CGT manufacturing are discussed. In particular, the authors highlight the role of fluorescent optical sensors, focusing on their strengths and weaknesses, for CGT manufacture. The review concludes by discussing how the integration of CGT manufacture and fluorescent optical sensors could augment future bioprocessing approaches.

  3. 19 CFR Appendix B to Part 191 - Sample Formats for Applications for Specific Manufacturing Drawback Rulings

    Science.gov (United States)

    2010-04-01

    ... rulings must be submitted to and reviewed and approved by CBP Headquarters. A specific manufacturing... Ruling Under 19 U.S.C. 1313(a) and 1313(b) (Combination) COMPANY LETTERHEAD (Optional) U.S. Customs and.... Customs will not approve an application which shows an unincorporated division or company as the applicant...

  4. 77 FR 67398 - Manufacturer of Controlled Substances; Notice of Application; INB Hauser Pharmaceutical Services...

    Science.gov (United States)

    2012-11-09

    ... DEPARTMENT OF JUSTICE Drug Enforcement Administration Manufacturer of Controlled Substances; Notice of Application; INB Hauser Pharmaceutical Services, Inc. Pursuant to Sec. 1301.33(a), Title 21 of... Pharmaceutical Services, Inc., 6880 N. Broadway, Suite H, Denver, Colorado 80221, made application by letter to...

  5. Commercial Off-The-Shelf (COTS) Electronics Reliability for Space Applications

    Science.gov (United States)

    Pellish, Jonathan

    2018-01-01

    This presentation describes the accelerating use of Commercial off the Shelf (COTS) parts in space applications. Component reliability and threats in the context of the mission, environment, application, and lifetime. Provides overview of traditional approaches applied to COTS parts in flight applications, and shows challenges and potential paths forward for COTS systems in flight applications it's all about data!

  6. Next-generation batteries and fuel cells for commercial, military, and space applications

    CERN Document Server

    Jha, A R

    2012-01-01

    Distilling complex theoretical physical concepts into an understandable technical framework, Next-Generation Batteries and Fuel Cells for Commercial, Military, and Space Applications describes primary and secondary (rechargeable) batteries for various commercial, military, spacecraft, and satellite applications for covert communications, surveillance, and reconnaissance missions. It emphasizes the cost, reliability, longevity, and safety of the next generation of high-capacity batteries for applications where high energy density, minimum weight and size, and reliability in harsh conditions are

  7. The commercial application prospect of HTGR plant in China

    International Nuclear Information System (INIS)

    Wang Yingsu

    2008-01-01

    With an introduction of the features and current situation of the HTGR power generation as well as the development of HTGR demonstration project in China, the article analyzes the necessity of developing HTGR power plants. The article proposes to exercise the advantages of HTGR to full extent so as to further develop HTGR power plants. It is believed that HTGR is of great commercial promotion value under appropriate circumstances. (authors)

  8. The commercial application of near real time materials accountancy

    International Nuclear Information System (INIS)

    Chater, S.P.; Jones, B.J.; Jones, R.F.; Westwood, L.N.; Wharrier, J.A.

    2001-01-01

    Full text: Near Real Time Materials Accountancy (NRTMA) is the leading edge technical solution employed by BNFL for in-process verification and timely detection of anomalies. It facilitates Safeguards inspection without intrusion and safeguards interim assurance without a monthly plant shut down. BNFL has been committed to the development of NRTMA for commercial plutonium plants. This multimedia poster presentation describes the features of Thorp and SMP relevant to the application of NRTMA, and then the statistical engine of NRTMA, which has many features in common across the two systems. This final point renders BNFL's implementation of NRTMA eligible for application to other nuclear and non-nuclear installations. NRTMA is operational in the Thermal Oxide Reprocessing Plant (Thorp). NRTMA supports fulfilment of the monthly timeliness component of the safeguards approach so that Thorp can remain operational between annual Physical Inventory Takings (PITs). The In-Process Inventory (IPI) is determined by for each vessel, or group of vessels, based on determination of weight and assay (or volume and concentration) or process models. Data trending enhances the quality of important sources of data. Plant status rules are used to determine times when it is appropriate to determine the IPI. The number of IPIs is currently some tens per annual campaign (PIT to PIT), although the NRTMA System can accommodate more. NRTMA is an intrinsic element in the safeguards and nuclear materials control and accountancy arrangements for the Sellafield MOX Plant (SMP). This fulfils the timeliness component of the safeguards approach and does not require monthly clean out or run down for verification. The SMP is a batch process. In a plant location, there is a 'Window of Opportunity' for determining that component of the inventory while it is stationary. The IPI can be determined when the 'Windows of Opportunity' for the entire Works Accountancy Area align. There are potentially many

  9. Application of lean manufacturing techniques in the Emergency Department.

    Science.gov (United States)

    Dickson, Eric W; Singh, Sabi; Cheung, Dickson S; Wyatt, Christopher C; Nugent, Andrew S

    2009-08-01

    "Lean" is a set of principles and techniques that drive organizations to continually add value to the product they deliver by enhancing process steps that are necessary, relevant, and valuable while eliminating those that fail to add value. Lean has been used in manufacturing for decades and has been associated with enhanced product quality and overall corporate success. To evaluate whether the adoption of Lean principles by an Emergency Department (ED) improves the value of emergency care delivered. Beginning in December 2005, we implemented a variety of Lean techniques in an effort to enhance patient and staff satisfaction. The implementation followed a six-step process of Lean education, ED observation, patient flow analysis, process redesign, new process testing, and full implementation. Process redesign focused on generating improvement ideas from frontline workers across all departmental units. Value-based and operational outcome measures, including patient satisfaction, expense per patient, ED length of stay (LOS), and patient volume were compared for calendar year 2005 (pre-Lean) and periodically after 2006 (post-Lean). Patient visits increased by 9.23% in 2006. Despite this increase, LOS decreased slightly and patient satisfaction increased significantly without raising the inflation adjusted cost per patient. Lean improved the value of the care we delivered to our patients. Generating and instituting ideas from our frontline providers have been the key to the success of our Lean program. Although Lean represents a fundamental change in the way we think of delivering care, the specific process changes we employed tended to be simple, small procedure modifications specific to our unique people, process, and place. We, therefore, believe that institutions or departments aspiring to adopt Lean should focus on the core principles of Lean rather than on emulating specific process changes made at other institutions.

  10. Simulation of Laser Additive Manufacturing and its Applications

    Science.gov (United States)

    Lee, Yousub

    Laser and metal powder based additive manufacturing (AM), a key category of advanced Direct Digital Manufacturing (DDM), produces metallic components directly from a digital representation of the part such as a CAD file. It is well suited for the production of high-value, customizable components with complex geometry and the repair of damaged components. Currently, the main challenges for laser and metal powder based AM include the formation of defects (e.g., porosity), low surface finish quality, and spatially non-uniform properties of material. Such challenges stem largely from the limited knowledge of complex physical processes in AM especially the molten pool physics such as melting, molten metal flow, heat conduction, vaporization of alloying elements, and solidification. Direct experimental measurement of melt pool phenomena is highly difficult since the process is localized (on the order of 0.1 mm to 1 mm melt pool size) and transient (on the order of 1 m/s scanning speed). Furthermore, current optical and infrared cameras are limited to observe the melt pool surface. As a result, fluid flows in the melt pool, melt pool shape and formation of sub-surface defects are difficult to be visualized by experiment. On the other hand, numerical simulation, based on rigorous solution of mass, momentum and energy transport equations, can provide important quantitative knowledge of complex transport phenomena taking place in AM. The overarching goal of this dissertation research is to develop an analytical foundation for fundamental understanding of heat transfer, molten metal flow and free surface evolution. Two key types of laser AM processes are studied: a) powder injection, commonly used for repairing of turbine blades, and b) powder bed, commonly used for manufacturing of new parts with complex geometry. In the powder injection simulation, fluid convection, temperature gradient (G), solidification rate (R) and melt pool shape are calculated using a heat transfer

  11. Guideline on evaluation and acceptance of commercial grade digital equipment for nuclear safety applications

    International Nuclear Information System (INIS)

    1996-10-01

    Nuclear power plants are increasingly upgrading their instrumentation and control (I ampersand C) systems with commercial digital equipment, which allows them to continue meeting safety and reliability requirements while controlling operating costs. However, the use of commercial software-based devices for safety related applications has raised new issues that impact design, procurement, and licensing activities. This guideline describes a consistent, comprehensive approach for the evaluation and acceptance of commercial digital equipment for nuclear safety systems

  12. Characterization of commercial supercapacitors for low temperature applications

    OpenAIRE

    Iwama, Etsuro; Taberna, Pierre-Louis; Azais, Philippe; Brégeon, Laurent; Simon, Patrice

    2012-01-01

    International audience; Electrochemical characterizations at low temperature and floating tests have been performed on 600F commercial supercapacitor (SC) for acetonitrile (AN)-based and AN + methyl acetate (MA) mixed electrolytes. From −40 to +20 °C, AN electrolyte showed slightly higher capacitance than those of AN + MA mixed electrolytes (25 and 33 vol.% of MA). At −55 °C, however, AN electrolyte did not cycle at all, while MA mixed electrolyte normally cycled with a slight decrease in the...

  13. 48 CFR 212.504 - Applicability of certain laws to subcontracts for the acquisition of commercial items.

    Science.gov (United States)

    2010-10-01

    ... laws to subcontracts for the acquisition of commercial items. 212.504 Section 212.504 Federal... PLANNING ACQUISITION OF COMMERCIAL ITEMS Applicability of Certain Laws to the Acquisition of Commercial Items 212.504 Applicability of certain laws to subcontracts for the acquisition of commercial items. (a...

  14. 48 CFR 12.504 - Applicability of certain laws to subcontracts for the acquisition of commercial items.

    Science.gov (United States)

    2010-10-01

    ... laws to subcontracts for the acquisition of commercial items. 12.504 Section 12.504 Federal Acquisition... Applicability of Certain Laws to the Acquisition of Commercial Items and Commercially Available Off-The-Shelf Items 12.504 Applicability of certain laws to subcontracts for the acquisition of commercial items. (a...

  15. Adaptation of commercial microscopes for advanced imaging applications

    Science.gov (United States)

    Brideau, Craig; Poon, Kelvin; Stys, Peter

    2015-03-01

    Today's commercially available microscopes offer a wide array of options to accommodate common imaging experiments. Occasionally, an experimental goal will require an unusual light source, filter, or even irregular sample that is not compatible with existing equipment. In these situations the ability to modify an existing microscopy platform with custom accessories can greatly extend its utility and allow for experiments not possible with stock equipment. Light source conditioning/manipulation such as polarization, beam diameter or even custom source filtering can easily be added with bulk components. Custom and after-market detectors can be added to external ports using optical construction hardware and adapters. This paper will present various examples of modifications carried out on commercial microscopes to address both atypical imaging modalities and research needs. Violet and near-ultraviolet source adaptation, custom detection filtering, and laser beam conditioning and control modifications will be demonstrated. The availability of basic `building block' parts will be discussed with respect to user safety, construction strategies, and ease of use.

  16. Carry-over of veterinary drugs from medicated to non-medicated feeds in commercial feed manufacturing plants

    NARCIS (Netherlands)

    Stolker, A.A.M.; Zuidema, T.; Egmond, van H.J.; Deckers, E.R.; Herbes, R.; Hooglught, J.; Olde Heuvel, E.; Jong, de J.

    2013-01-01

    Different compound feeds have to be manufactured in the same production line. As a consequence, traces of the first produced feed may remain in the production and get mixed with the next feed batches. This "carry-over" is unavoidable, and so non-medicated feed can be contaminated with veterinary

  17. Manufacture and Drug Delivery Applications of Silk Nanoparticles.

    Science.gov (United States)

    Wongpinyochit, Thidarat; Johnston, Blair F; Seib, F Philipp

    2016-10-08

    Silk is a promising biopolymer for biomedical and pharmaceutical applications due to its outstanding mechanical properties, biocompatibility and biodegradability, as well its ability to protect and subsequently release its payload in response to a trigger. While silk can be formulated into various material formats, silk nanoparticles are emerging as promising drug delivery systems. Therefore, this article covers the procedures for reverse engineering silk cocoons to yield a regenerated silk solution that can be used to generate stable silk nanoparticles. These nanoparticles are subsequently characterized, drug loaded and explored as a potential anticancer drug delivery system. Briefly, silk cocoons are reverse engineered first by degumming the cocoons, followed by silk dissolution and clean up, to yield an aqueous silk solution. Next, the regenerated silk solution is subjected to nanoprecipitation to yield silk nanoparticles - a simple but powerful method that generates uniform nanoparticles. The silk nanoparticles are characterized according to their size, zeta potential, morphology and stability in aqueous media, as well as their ability to entrap a chemotherapeutic payload and kill human breast cancer cells. Overall, the described methodology yields uniform silk nanoparticles that can be readily explored for a myriad of applications, including their use as a potential nanomedicine.

  18. Development of Smart Active Layer Sensor (II): Manufacturing and Application

    International Nuclear Information System (INIS)

    Lee, Young Sup; Lee, Sang Il; Kwon, Jae Hwa; Yoon, Dong Jin

    2004-01-01

    This paper is the second part of the study on the development of a smart active layer (SAL) sensor, which consists of two parts. As mentioned in the first paper, structural health monitoring (SHM) is a new technology that is being increasingly applied at the industrial field as a potential approach to improve cost and convenience of structural inspection. Recently, the development of smart sensor is very active for real application. This study has focused on preparation and application study of SAL sensor which is described with regard to the theory and concept of the SAL sensor in the first paper. In order to detect elastic wave, smart piezoelectric sensor, SAL, is fabricated by using a piezoelectric element, shielding layer and protection layer. This protection layer plays an important role in a patched network of distributed piezoelectric sensor and shielding treatment. Four types of SAL sensor are designed/prepared/tested, and these details will be discussed in the paper In this study, SAL sensor ran be feasibly applied to perform structural health monitoring and to detect damage sources which result in elastic waves

  19. Modelling streamflow reductions resulting from commercial afforestation in South Africa: From research to application

    CSIR Research Space (South Africa)

    Gush, Mark B

    2006-08-01

    Full Text Available , in 1972, of legislation that required timber growers to apply for permits to establish commercial plantations. Applications to establish forestry plantations became mandatory, and were rejected if it was deemed that the afforestation would use...

  20. 76 FR 16379 - Foreign-Trade Zone 177-Evansville, IN; Application for Manufacturing Authority, Best Chair, Inc...

    Science.gov (United States)

    2011-03-23

    ...--Evansville, IN; Application for Manufacturing Authority, Best Chair, Inc. d/b/a Best Home Furnishings... Zones Board (the Board) by the Ports of Indiana, grantee of FTZ 177, requesting manufacturing authority on behalf of Best Chair, Inc. d/b/a Best Home Furnishings (Best Home), to manufacture upholstered...

  1. Trends in genetic patent applications: The commercialization of academic intellectual property

    NARCIS (Netherlands)

    Kers, J.G.; van Burg, J.C.; Stoop, T.; Cornel, M.C.

    2014-01-01

    We studied trends in genetic patent applications in order to identify the trends in the commercialization of research findings in genetics. To define genetic patent applications, the European version (ECLA) of the International Patent Classification (IPC) codes was used. Genetic patent applications

  2. Application of commercial exploration techniques to site selection and characterization

    International Nuclear Information System (INIS)

    Brewer, W.A.

    1987-01-01

    Since 1976 the U.S Department of Energy has conducted intensive geologic studies of the Hanford Nuclear Reservation in south-central Washington. With passage of the Nuclear Waste Policy Act of 1982 the process of search for a geologically suitable waste repository site became more structured, and it has been subject to outside review by the state, affected Indian tribes and other federal agencies, notably the Nuclear Regulatory Commission and the U.S Geological Survey. This paper contrasts the USDOE approach with that of the mining and petroleum industries, highlighting fundamental differences in philosophy and techniques. It is proposed that the principle of ''condemnation,'' which is fundamental in commercial exploration methods, could greatly benefit the USDOE siting program, which by comparison has been slow, costly and not very productive

  3. Slightly Conductive Transparent Films for Space Applications: Manufacturability and Durability

    Science.gov (United States)

    Uppala, N.; Griffin, J.; Vemulapalli, J.; Hambourger, P. D.

    2001-01-01

    Highly transparent, slightly conductive films of co-deposited indium tin oxide (ITO) and MgF, have possible applications for environmental protection of exterior surfaces of spacecraft. Reliable preparation of films with the desired sheet resistivity (approximately 10(exp 8) ohms/square) is difficult because the electrical properties of ITO-Mg F, are highly dependent on film composition. We have investigated the use of plasma emission monitoring to improve the reproducibility of films prepared by RF magnetron sputtering. While considerable improve ment was observed, it appears that some in-situ electrical or optica l characterization will be needed for reliable production coating wit h ITO-MgF,. We have also done further evaluation of a possibly undesi rable photoconductive effect previously observed in these films.

  4. Manufacturing of copper-graphite brushes for automobile applications

    International Nuclear Information System (INIS)

    Answar, M.Y.

    2006-01-01

    Copper-graphite brushes are used in high-volume automotive applications, such as ignition switches, window lifts, wiper motors, engine cooling fans, ABS break system and seat actuators etc. The amount of graphite in these brushes may range from 5 -20 wt. %. In this paper, some of the results of a study carried out using locally produced electrolytic copper powder and imported graphite powder are being summarized. The green compacts were produced by compaction at 650 MPa. These compacts were sintered at temperatures between 950 to 1050 degree C for various time intervals. The effects of sintering temperatures and time on the properties are analyzed. The influence of small additions of zinc on hardness of the sintered alloy compacts is also investigated. (author)

  5. Applications of multi-criteria and game theory approaches manufacturing and logistics

    CERN Document Server

    Hennet, Jean-Claude; Tiwari, Manoj

    2014-01-01

    Aligning the latest practices, innovations and case studies with academic frameworks and theories, the broad area of multi-criteria and game theory applications in manufacturing and logistics is covered in comprehensive details. Part 1 presents ‘multi-criteria applications’ and includes chapters on  logistics with a focus on vehicle routing problems, a multi-objective decision making approach to select the best storage policy and an exploratory study to predict the most important factors that can lead to successful mobile supply chain management adoption for manufacturing firms. Part 2 covers ‘game theory applications’ and encompasses the process of forming a coalition within a corporate network to the problem of integrating inventory and distribution optimization together with game theory to effectively manage supply networks. Providing a forum to investigate, exchange novel ideas and disseminate knowledge covering the broad area of multi-criteria and game theory applications in manufacturing and l...

  6. A study on the applicability of just-in-time in manufacturing of ethanol

    Directory of Open Access Journals (Sweden)

    Marcelo Giroto Rebelato

    2012-08-01

    Full Text Available The aim of this paper is to analyze the applicability of the Just-in-Time (JIT System in manufacturing of ethanol. For this, were selected from the specialized literature the requirements that make up the JIT System so that each requirement identified was confronted to the characteristics and peculiarities of the process and current technology of producing ethanol. We conclude that, although the most significant requirement of the JIT system, manufacturing in the rhythm of "customer pull" is not possible in the manufacture of ethanol given the peculiar characteristic of its main raw material, sugarcane, we conclude that JIT is applicable to the ethanol production system and can bring real benefits to companies that adopt it.

  7. [Manufacture and clinical application of 215 IPS-Empress casting ceramic restorations].

    Science.gov (United States)

    Zhao, Na; Zhou, Jian

    2008-08-01

    To explore the manufacture and clinical application of IPS-Empress casting ceramic restorations. The problems in manufacture and clinical operation of 215 casting ceramic restorations were analyzed. In 215 casting ceramic restorations, 12 (5.58%) casting ceramic restorations were affected by clinical design or application, 15 (6.98%) casting ceramic restorations were affected by some manufacture problems, and 14 (6.51%) casting ceramic restorations were affected by clinical try-in. Through 2-3 years' follow-up, the achievement ratio of 215 IPS-Empress casting ceramic restorations was 94.88%, and 11 casting ceramic restorations were affected by some problems. Beauty and simultaneous enamel wear are the characteristics of casting ceramic restorations. But because of its brittle, the indications should be strictly selected.

  8. Manufacture of a ceramic paper for art applications

    Science.gov (United States)

    Dölle, K.; Honig, A.; Piatkowski, J.; Kuempel, C.

    2018-01-01

    Ceramic paper products are mostly used as high temperature ceramic insulation products. They offer an effective solution for most demanding heat management and insulation applications. The objective for this research project was to create a ceramic paper like product that combines the advantages of paper fibers, ceramic filler, and a clay product into one product, which can be produced on a continuous base with a paper machine. The produced ceramic paper product had a ceramic filler level between 59.68% and 78.8% with a basis weight between 322.9 g/m² and 693.7 g/m², and a final moisture content of 58.6% to 44.7% respectively. The wooden fiber served as a support medium for the ceramic filler material during production on the paper machine and during the conversion process into art pieces. During firing in a kiln, the fiber material combusted and the ceramic filler material mixture acts as common pottery clay, holding the desired shape of the art pieces produced.

  9. Response of commercial photodiodes for application in alpha spectrometry

    International Nuclear Information System (INIS)

    Ferreira Filho, Alfredo Lopes

    1998-06-01

    The use of semiconductor detector for ionizing radiations spectrometry and dosimetry has been growing in the last years due to its characteristics of fast response, good efficiency for unit of volume and excellent resolution. Since the working principle of a semiconductor detector is identical to that of the semiconductor junctions of commercial electronic devices, a study was carried out on the PIN-photodiodes response, aiming at set up an alpha spectrometry system of low cost and easy acquisition. The tested components have the following characteristics: active area varying between 13.2 and 25 mm 2 , window of thickness equal or lower than 57 mg/cm 2 , depletion area with depth ranging from 10 to 300 μm and junction capacitance of 16 to 20 pF.Am-241, Cm-244, U-233 and Np-237 alpha sources produced by electrodeposition were used to evaluate the response of the devices as a function of the radiation energy. The results have shown a linear response of the photodiodes with the incident alpha particle energy. The resolution varied from 1.6% to 0.45% and the better detection efficiency found was about 7.2. The low cost of the photodiodes and the excellent results obtained at room temperature make such components very attractive for teaching purposes for environmental monitoring. (author)

  10. Characterization of commercial supercapacitors for low temperature applications

    Science.gov (United States)

    Iwama, E.; Taberna, P. L.; Azais, P.; Brégeon, L.; Simon, P.

    2012-12-01

    Electrochemical characterizations at low temperature and floating tests have been performed on 600F commercial supercapacitor (SC) for acetonitrile (AN)-based and AN + methyl acetate (MA) mixed electrolytes. From -40 to +20 °C, AN electrolyte showed slightly higher capacitance than those of AN + MA mixed electrolytes (25 and 33 vol.% of MA). At -55 °C, however, AN electrolyte did not cycle at all, while MA mixed electrolyte normally cycled with a slight decrease in their capacitance. From electrochemical impedance spectroscopy measurements, the whole resistance for AN-based cells at -55 °C was found to be about 10,000 times higher than that of +20 °C, while a 40-fold increase in the cell resistance was obtained for the MA mixture between 20 and -55 °C. From the results of floating tests at 2.7 V and 60 °C for 1 month, the 25 vol.% MA mixture showed no change and slight decreased but stable capacitance.

  11. Thermal characterization of commercially pure titanium for dental applications

    Directory of Open Access Journals (Sweden)

    Enori Gemelli

    2007-09-01

    Full Text Available Thermal characterization of commercially pure titanium was carried out in dry air to investigate the oxidation kinetics, the oxide structures and their properties. Oxidation kinetics were performed by thermogravimetry in isothermal conditions between 300 and 750 °C for 48 hours and the oxide structures were studied by differential thermal analyses and X ray diffraction between room temperature and 1000 °C. The oxidation kinetic increases with temperature and is very fast in the initial period of oxidation, decreasing rapidly with time, especially up to 600 °C. Kinetic laws varied between the inverse logarithmic for the lower temperatures (300 and 400 °C and the parabolic for the higher temperatures (650, 700 and 750 °C. Evidences from X ray diffraction and differential thermal analyses showed that crystallization of the passive oxide film, formed at room temperature, into anatase occurs at about 276 °C. The crystallized oxide structure is composed of anatase between 276 and 457 °C, anatase and rutile sublayers between 457 and 718 °C, and a pure layer of rutile after 718 °C. Rockwell-C adhesion tests reveled that the oxide films formed up to 600 °C have a good adhesion. Vickers indentations on the oxidized surfaces showed that the hardness of the oxide film, measured at 600 and 650 °C, is approximately 9500 MPa. At these temperatures the surface roughness varied between 0.90 and 1.30 mm.

  12. 77 FR 67397 - Manufacturer of Controlled Substances; Notice of Application; Johnson Matthey, Inc.

    Science.gov (United States)

    2012-11-09

    ...; Notice of Application; Johnson Matthey, Inc. Pursuant to Sec. 1301.33(a), Title 21 of the Code of Federal Regulations (CFR), this is notice that on September 10, 2012, Johnson Matthey, Inc., Pharmaceuticals Materials... Thebaine (9333) II The company plans to manufacture the listed controlled substances in bulk for...

  13. 77 FR 30026 - Manufacturer of Controlled Substances; Notice of Application; Johnson Matthey, Inc.

    Science.gov (United States)

    2012-05-21

    ...; Notice of Application; Johnson Matthey, Inc. Pursuant to Sec. 1301.33(a), Title 21 of the Code of Federal Regulations (CFR), this is notice that on March 26, 2012, Johnson Matthey, Inc., Custom Pharmaceuticals...), a basic class of controlled substance listed in schedule II. The company plans to manufacture the...

  14. 77 FR 67676 - Manufacturer of Controlled Substances; Notice of Application; Johnson Matthey Inc.

    Science.gov (United States)

    2012-11-13

    ...; Notice of Application; Johnson Matthey Inc. Pursuant to Sec. 1301.33(a), Title 21 of the Code of Federal Regulations (CFR), this is notice that on September 10, 2012, Johnson Matthey Inc., Custom Pharmaceuticals... Remifentanil (9739) II Sufentanil (9740) II Fentanyl (9801) II The company plans to manufacture the listed...

  15. 78 FR 30332 - Manufacturer of Controlled Substances, Notice of Application, Austin Pharma, Llc.

    Science.gov (United States)

    2013-05-22

    ... DEPARTMENT OF JUSTICE Drug Enforcement Administration Manufacturer of Controlled Substances, Notice of Application, Austin Pharma, Llc. Pursuant to Sec. 1301.33(a), Title 21 of the Code of Federal Regulations (CFR), this is notice that on March 28, 2013, Austin Pharma, LLC., 811 Paloma Drive, Suite C...

  16. 77 FR 30027 - Manufacturer of Controlled Substances; Notice of Application; Austin Pharma, LLC.

    Science.gov (United States)

    2012-05-21

    ... DEPARTMENT OF JUSTICE Drug Enforcement Administration Manufacturer of Controlled Substances; Notice of Application; Austin Pharma, LLC. Pursuant to Sec. 1301.33(a), Title 21 of the Code of Federal Regulations (CFR), this is notice that on April 11, 2012, Austin Pharma, LLC., 811 Paloma Drive, Suite C...

  17. 77 FR 34073 - Manufacturer of Controlled Substances; Notice of Application; S&B Pharma, Inc.

    Science.gov (United States)

    2012-06-08

    ... DEPARTMENT OF JUSTICE Drug Enforcement Administration Manufacturer of Controlled Substances; Notice of Application; S&B Pharma, Inc. Pursuant to Sec. 1301.33(a), Title 21 of the Code of Federal Regulations (CFR), this is notice that on April 4, 2012, S&B Pharma Inc., 405 South Motor Avenue, Azusa...

  18. 78 FR 46613 - Manufacturer of Controlled Substances; Notice of Application; Siegfried (USA), LLC

    Science.gov (United States)

    2013-08-01

    ... DEPARTMENT OF JUSTICE Drug Enforcement Administration Manufacturer of Controlled Substances; Notice of Application; Siegfried (USA), LLC Pursuant to Sec. 1301.33(a), Title 21 of the Code of Federal Regulations (CFR), this is notice that on June 10, 2013, Siegfried (USA), LLC., 33 Industrial Park Road...

  19. 78 FR 5500 - Manufacturer of Controlled Substances, Notice of Application; Siegfried (USA)

    Science.gov (United States)

    2013-01-25

    ... DEPARTMENT OF JUSTICE Drug Enforcement Administration Manufacturer of Controlled Substances, Notice of Application; Siegfried (USA) Pursuant to Sec. 1301.33(a), Title 21 of the Code of Federal Regulations (CFR), this is notice that on June 19, 2012, Siegfried (USA), 33 Industrial Park Road, Pennsville...

  20. 77 FR 70825 - Manufacturer of Controlled Substances; Notice of Application; Siegfried (USA), LLC

    Science.gov (United States)

    2012-11-27

    ... DEPARTMENT OF JUSTICE Drug Enforcement Administration Manufacturer of Controlled Substances; Notice of Application; Siegfried (USA), LLC Pursuant to Sec. 1301.33(a), Title 21 of the Code of Federal Regulations (CFR), this is notice that on November 5, 2012, Siegfried (USA) LLC, 33 Industrial Park Road...

  1. 78 FR 32458 - Manufacturer of Controlled Substances; Notice of Application; Siegfried USA, LLC

    Science.gov (United States)

    2013-05-30

    ... DEPARTMENT OF JUSTICE Drug Enforcement Administration Manufacturer of Controlled Substances; Notice of Application; Siegfried USA, LLC Pursuant to Sec. 1301.33(a), Title 21 of the Code of Federal Regulations (CFR), this is notice that on April 18, 2013, Siegfried USA, LLC., 33 Industrial Park Road...

  2. 77 FR 47108 - Manufacturer of Controlled Substances; Notice of Application; Cerilliant Corporation

    Science.gov (United States)

    2012-08-07

    ... DEPARTMENT OF JUSTICE Drug Enforcement Administration Manufacturer of Controlled Substances; Notice of Application; Cerilliant Corporation Pursuant to Title 21 Code of Federal Regulations 1301.34 (a), this is notice that on July 6, 2012, Cerilliant Corporation, 811 Paloma Drive, Suite A, Round Rock...

  3. 77 FR 52366 - Manufacturer of Controlled Substances; Notice of Application; Cerilliant Corporation

    Science.gov (United States)

    2012-08-29

    ... DEPARTMENT OF JUSTICE Drug Enforcement Administration Manufacturer of Controlled Substances; Notice of Application; Cerilliant Corporation Pursuant to Sec. 1301.33(a), Title 21 of the Code of Federal Regulations (CFR), this is notice that on July 16, 2012, Cerilliant Corporation, 811 Paloma Drive...

  4. 78 FR 54917 - Manufacturer of Controlled Substances; Notice of Application; Cerilliant Corporation

    Science.gov (United States)

    2013-09-06

    ... DEPARTMENT OF JUSTICE Drug Enforcement Administration Manufacturer of Controlled Substances; Notice of Application; Cerilliant Corporation Pursuant to Sec. 1301.33(a), Title 21 of the Code of Federal Regulations (CFR), this is notice that on July 10, 2013, Cerilliant Corporation, 811 Paloma Drive...

  5. 78 FR 5499 - Manufacturer of Controlled Substances; Notice of Application; Cerilliant Corporation

    Science.gov (United States)

    2013-01-25

    ... DEPARTMENT OF JUSTICE Drug Enforcement Administration Manufacturer of Controlled Substances; Notice of Application; Cerilliant Corporation Pursuant to Sec. 1301.33(a), Title 21 of the Code of Federal Regulations (CFR), this is notice that on October 4, 2012, Cerilliant Corporation, 811 Paloma...

  6. 77 FR 19717 - Manufacturer of Controlled Substances; Notice of Application; Cerilliant Corporation

    Science.gov (United States)

    2012-04-02

    ... DEPARTMENT OF JUSTICE Drug Enforcement Administration Manufacturer of Controlled Substances; Notice of Application; Cerilliant Corporation Pursuant to Sec. 1301.33(a), Title 21 of the Code of Federal Regulations (CFR), this is notice that on February 17, 2012, Cerilliant Corporation, 811 Paloma...

  7. 77 FR 43863 - Manufacturer of Controlled Substances; Notice of Application; Boehringer Ingelheim Chemicals Inc.

    Science.gov (United States)

    2012-07-26

    ... DEPARTMENT OF JUSTICE Drug Enforcement Administration Manufacturer of Controlled Substances; Notice of Application; Boehringer Ingelheim Chemicals Inc. Pursuant to Sec. 1301.33(a), Title 21 of the Code of Federal Regulations (CFR), this is notice that on June 8, 2012, Boehringer Ingelheim Chemicals...

  8. 78 FR 39340 - Manufacturer of Controlled Substances; Notice of Application; Boehringer Ingelheim Chemicals, Inc.

    Science.gov (United States)

    2013-07-01

    ... DEPARTMENT OF JUSTICE Drug Enforcement Administration Manufacturer of Controlled Substances; Notice of Application; Boehringer Ingelheim Chemicals, Inc. Pursuant to Sec. 1301.33(a), Title 21 of the Code of Federal Regulations (CFR), this is notice that on May 31, 2013, Boehringer Ingelheim Chemicals...

  9. 75 FR 57519 - Weather Shield Manufacturing, Medford, WI; Notice of Negative Determination Regarding Application...

    Science.gov (United States)

    2010-09-21

    ... DEPARTMENT OF LABOR Employment and Training Administration [TA-W-72,673] Weather Shield...), applicable to workers and former workers of Weather Shield Manufacturing, Inc., Medford, Wisconsin (subject... administrative support services related to the production of doors and windows at various Weather Shield...

  10. The scope of additive manufacturing in cryogenics, component design, and applications

    NARCIS (Netherlands)

    Stautner, W.; Vanapalli, S.; Weiss, K.-P.; Chen, R.; Amm, K.; Budesheim, E.; Ricci, J.

    2017-01-01

    Additive manufacturing techniques using composites or metals are rapidly gaining momentum in cryogenic applications. Small or large, complex structural components are now no longer limited to mere design studies but can now move into the production stream thanks to new machines on the market that

  11. 75 FR 4343 - Foreign-Trade Zone 22-Chicago, IL; Application for Manufacturing Authority; LG Electronics...

    Science.gov (United States)

    2010-01-27

    ... DEPARTMENT OF COMMERCE Foreign-Trade Zones Board [Docket 3-2010] Foreign-Trade Zone 22--Chicago, IL; Application for Manufacturing Authority; LG Electronics MobileComm USA, Inc. (Cell Phone Kitting... authority on behalf of LG Electronics MobileComm USA, Inc. (LGEMU), located in Bolingbrook, Illinois. The...

  12. 75 FR 17691 - Foreign-Trade Zone 196 - Fort Worth, Texas, Application for Manufacturing Authority, ATC...

    Science.gov (United States)

    2010-04-07

    ... Worth, Texas, Application for Manufacturing Authority, ATC Logistics & Electronics (Cell Phone Kitting... million unit capacity) is used for the kitting and distribution of cell phones. Components and materials sourced from abroad (representing 96% of the value of the finished product) include: cell phone batteries...

  13. Review of data mining applications for quality assessment in manufacturing industry: support vector machines

    Directory of Open Access Journals (Sweden)

    Rostami Hamidey

    2015-01-01

    Full Text Available In many modern manufacturing industries, data that characterize the manufacturing process are electronically collected and stored in databases. Due to advances in data collection systems and analysis tools, data mining (DM has widely been applied for quality assessment (QA in manufacturing industries. In DM, the choice of technique to be used in analyzing a dataset and assessing the quality depend on the understanding of the analyst. On the other hand, with the advent of improved and efficient prediction techniques, there is a need for an analyst to know which tool performs better for a particular type of dataset. Although a few review papers have recently been published to discuss DM applications in manufacturing for QA, this paper provides an extensive review to investigate the application of a special DM technique, namely support vector machine (SVM to deal with QA problems. This review provides a comprehensive analysis of the literature from various points of view as DM concepts, data preprocessing, DM applications for each quality task, SVM preliminaries, and application results. Summary tables and figures are also provided besides to the analyses. Finally, conclusions and future research directions are provided.

  14. 78 FR 64018 - Manufacturer of Controlled Substances; Notice of Application; GE Healthcare

    Science.gov (United States)

    2013-10-25

    ... DEPARTMENT OF JUSTICE Drug Enforcement Administration Manufacturer of Controlled Substances; Notice of Application; GE Healthcare Pursuant to Sec. 1301.33(a), Title 21 of the Code of Federal Regulations (CFR), this is notice that on September 12, 2013, GE Healthcare, 3350 North Ridge Avenue...

  15. 78 FR 12103 - Manufacturer of Controlled Substances; Notice of Application; GE Healthcare

    Science.gov (United States)

    2013-02-21

    ... DEPARTMENT OF JUSTICE Drug Enforcement Administration Manufacturer of Controlled Substances; Notice of Application; GE Healthcare Pursuant to Sec. 1301.33(a), Title 21 of the Code of Federal Regulations (CFR), this is notice that on August 31, 2012, GE Healthcare, 3350 North Ridge Avenue, Arlington...

  16. 78 FR 51210 - Manufacturer of Controlled Substances; Notice of Application; Halo Pharmaceutical, Inc.

    Science.gov (United States)

    2013-08-20

    ... DEPARTMENT OF JUSTICE Drug Enforcement Administration Manufacturer of Controlled Substances; Notice of Application; Halo Pharmaceutical, Inc. Pursuant to Sec. 1301.33(a), Title 21 of the Code of Federal Regulations (CFR), this is notice that on July 8, 2013, Halo Pharmaceutical, Inc., 30 North...

  17. 77 FR 47114 - Manufacturer of Controlled Substances; Notice of Application; Halo Pharmaceutical Inc.

    Science.gov (United States)

    2012-08-07

    ... DEPARTMENT OF JUSTICE Drug Enforcement Administration Manufacturer of Controlled Substances; Notice of Application; Halo Pharmaceutical Inc. Pursuant to Sec. 1301.33(a), Title 21 of the Code of Federal Regulations (CFR), this is notice that on July 6, 2012, Halo Pharmaceutical Inc., 30 North...

  18. Middle and small manufacture enterprise e-commerce application systems research

    Science.gov (United States)

    Zhu, Mingqiang

    2017-04-01

    With the extensive application of electronic commerce in manufacturing enterprises, e-commerce the influence of operation is increasingly becoming the focus of academic and business circles on the basis, this paper probes into the influence of e-commerce on the operation of the enterprise for the manufacturing enterprises to correctly understand the performance of e-commerce to provide a little help. The article first analyses e-commerce new environment on medium manufacturing enterprise requires, current medium manufacturing enterprise achieved e-commerce has many difficult, should e-commerce correctly awareness, and full planning, and points step implementation, and e-commerce and enterprise integration, and construction features of e-commerce platform, and procurement and supply chain of collaborative management, and attention customer management, and variety e-commerce of mode mixed, and flexible effective operations, and logistics socialization, views, focus on small and medium manufacturing enterprises in e-commerce applications to be innovative in design, production and management of agile and flexible production strategies.

  19. The impact of fit manufacturing on green manufacturing: A review

    Science.gov (United States)

    Qi, Ang Nian; Sin, Tan Chan; Fathullah, M.; Lee, C. C.

    2017-09-01

    Fit manufacturing and Green manufacturing are a new trend principle and concept. They are getting popular in industrial. This paper is identifying the impact between Fit manufacturing and Green manufacturing. Besides Fit manufacturing, Lean manufacturing, Agile manufacturing and Sustainable manufacturing gives big impacts to Green Manufacturing. On top of that, this paper also discuss the benefits of applying Fit manufacturing and Green manufacturing in industrial as well as environment. Hence, applications of Fit manufacturing and Green Manufacturing are increasing year by year.

  20. Strength analysis and modeling of cellular lattice structures manufactured using selective laser melting for tooling applications

    DEFF Research Database (Denmark)

    Mahshid, Rasoul; Hansen, Hans Nørgaard; Loft Højbjerre, Klaus

    2016-01-01

    Additive manufacturing is rapidly developing and gaining popularity for direct metal fabrication systems like selective laser melting (SLM). The technology has shown significant improvement for high-quality fabrication of lightweight design-efficient structures such as conformal cooling channels...... in injection molding tools and lattice structures. This research examines the effect of cellular lattice structures on the strength of workpieces additively manufactured from ultra high-strength steel powder. Two commercial SLM machines are used to fabricate cellular samples based on four architectures— solid......, hollow, lattice structure and rotated lattice structure. Compression test is applied to the specimens while they are deformed. The analytical approach includes finite element (FE), geometrical and mathematical models for prediction of collapse strength. The results from the the models are verified...

  1. Strength analysis and modeling of cellular lattice structures manufactured using selective laser melting for tooling applications

    DEFF Research Database (Denmark)

    Mahshid, Rasoul; Hansen, Hans Nørgaard; Loft Højbjerre, Klaus

    2016-01-01

    in injection molding tools and lattice structures. This research examines the effect of cellular lattice structures on the strength of workpieces additively manufactured from ultra high-strength steel powder. Two commercial SLM machines are used to fabricate cellular samples based on four architectures— solid...... with experimental data and it is shown that they agree well. The results from this research show that using lattice structures significantly reduces the strength of material with respect to solid samples while indicating no serious increase of strength compared to hollow structures. In combination with an analysis...

  2. The Application of the Method of Continuous Casting for Manufacturing of Welding Wire AMg6

    International Nuclear Information System (INIS)

    Azhazha, V.M.; Sverdlov, V.Ya.; Kondratov, A.A.; Rudycheva, T.Yu.

    2007-01-01

    The method of manufacturing semifinished item of high alloyed of aluminum, silver and copper alloys has been investigated on the basis of the continuous casting method. The sample of aluminum alloy AMg6 consist of small grains with the vios-cut dimension ∼ 15 mkm and which are stretched in the direction of longitudinal axis of the sample Such microstructure is favourable for plastic deformation of the sample. Welding wire which meets the demands of standards of commercial welding wires of this brand has been produced by the drawing from the sample

  3. Commercializing potassium terbium fluoride, KTF (KTb3F10) faraday crystals for high laser power optical isolator applications

    Science.gov (United States)

    Schlichting, Wolfgang; Stevens, Kevin; Foundos, Greg; Payne, Alexis

    2017-10-01

    Many scientific lasers and increasingly industrial laser systems operate in manufacture. However, for high-power laser applications TGG is limited by its absorption at 1064nm and its thermo-optic coefficient, dn/dT. Specifically, thermal lensing and depolarization effects become a limiting factor at high laser powers. While TGG absorption has improved significantly over the past few years, there is an intrinsic limit. Now, SYNOPTICS is commercializing the enhanced new crystal Potassium Terbium Fluoride KTF (KTb3F10) that exhibits much smaller nonlinear refractive index and thermo-optic coefficients, and still exhibits a Verdet constant near that of TGG. This cubic crystal has relatively low absorption and thermo-optic coefficients. It is now fully characterized and available for select production orders. At OPTIFAB in October 2017 we present recent results comparing the performance of KTF to TGG in optical isolators and show SYNOPTICS advances in large volume crystal growth and the production ramp up.

  4. Center for commercial applications of combustion in space (CCACS); A partnership for space commercialization at the Colorado School of Mines

    Science.gov (United States)

    Schowengerdt, F. D.; Kee, Bob; Linne, Mark; McKinnon, Tom; Moore, John; Parker, Terry; Readey, Dennis; Tilton, John E.; Helble, Joe

    1997-01-01

    The Center for Commercial Applications of Combustion in Space (CCACS) is a NASA/Industry/University consortium at the Colorado School of Mines (CSM). The mission of the Center is to assist industry in developing commercial products by conducting combustion research which takes advantage of the unique properties of space. By conducting experiments in near-zero gravity, convection and buoyancy effects can be minimized and new fundamental design-related knowledge can be gained which can be used to improve combustion-related products and processes on earth. Companies, government laboratories and universities most actively involved in CCACS at present include ABB Combustion, ADA Technologies, Advanced Refractory Technologies, Golden Technologies, Lockheed-Martin, Southwest Sciences, Space Systems/Lora, NASA-Lewis, JPL, the Baylor Dental School and the University of Connecticut. Products and processes of interest to the Center participants include industrial process combustors; catalytic combustion; Halon replacements; ceramic powders, whiskers and fibers; metal-matrix composites; NiTi for bone replacement; diamond coatings for oil-well drill bits; zeolites; imaging sensor arrays and other instrumentation for flame and particulate diagnostics. The center also assists member companies in marketing the resulting products and processes.

  5. A model to enable indirect manufacturing options transactions between organisations: An application to the ceramic industry

    International Nuclear Information System (INIS)

    Rodriguez-Rodriguez, R.; Gomez-Gasquet, P.; Oltra-Badenes, R. F.

    2014-01-01

    In the current competitive contexts, it is widely accepted and proved that inter-enterprise collaboration lead in many occasions to better results. The Spanish ceramic industry must improve, dropping its manufacturing costs in order to be able to compete with low cost products coming from Asia. In this sense, this work presents the main results obtained from applying an innovative model, which facilitates the transfer of manufacturing options between two ceramic enterprises that share a common supplier in the scenario where one of them needs more manufacturing capacity than the one booked according to its demand forecast and the another need less. Then, some decisional mechanisms are applied, which output the values for certain parameters in order to augment the benefit of all the three participants. With the application of this model better organisational results both economic and of service level are achieved. (Author)

  6. Usability of Commercially Available Mobile Applications for Diverse Patients.

    Science.gov (United States)

    Sarkar, Urmimala; Gourley, Gato I; Lyles, Courtney R; Tieu, Lina; Clarity, Cassidy; Newmark, Lisa; Singh, Karandeep; Bates, David W

    2016-12-01

    Mobile applications or 'apps' intended to help people manage their health and chronic conditions are widespread and gaining in popularity. However, little is known about their acceptability and usability for low-income, racially/ethnically diverse populations who experience a disproportionate burden of chronic disease and its complications. The objective of this study was to investigate the usability of existing mobile health applications ("apps") for diabetes, depression, and caregiving, in order to facilitate development and tailoring of patient-facing apps for diverse populations. Usability testing, a mixed-methods approach that includes interviewing and direct observation of participant technology use, was conducted with participants (n = 9 caregivers; n = 10 patients with depression; and n = 10 patients with diabetes) on a total of 11 of the most popular health apps (four diabetes apps, four depression apps, and three caregiver apps) on both iPad and Android tablets. The participants were diverse: 15 (58 %) African Americans, seven (27 %) Whites, two (8 %) Asians, two (8 %) Latinos with either diabetes, depression, or who were caregivers. Participants were given condition-specific tasks, such as entering a blood glucose value into a diabetes app. Participant interviews were video recorded and were coded using standard methods to evaluate attempts and completions of tasks. We performed inductive coding of participant comments to identify emergent themes. Participants completed 79 of 185 (43 %) tasks across 11 apps without assistance. Three themes emerged from participant comments: lack of confidence with technology, frustration with design features and navigation, and interest in having technology to support their self-management. App developers should employ participatory design strategies in order to have an impact on chronic conditions such as diabetes and depression that disproportionately affect vulnerable populations. While patients

  7. A novel classification and online platform for planning and documentation of medical applications of additive manufacturing.

    Science.gov (United States)

    Tuomi, Jukka; Paloheimo, Kaija-Stiina; Vehviläinen, Juho; Björkstrand, Roy; Salmi, Mika; Huotilainen, Eero; Kontio, Risto; Rouse, Stephen; Gibson, Ian; Mäkitie, Antti A

    2014-12-01

    Additive manufacturing technologies are widely used in industrial settings and now increasingly also in several areas of medicine. Various techniques and numerous types of materials are used for these applications. There is a clear need to unify and harmonize the patterns of their use worldwide. We present a 5-class system to aid planning of these applications and related scientific work as well as communication between various actors involved in this field. An online, matrix-based platform and a database were developed for planning and documentation of various solutions. This platform will help the medical community to structurally develop both research innovations and clinical applications of additive manufacturing. The online platform can be accessed through http://www.medicalam.info. © The Author(s) 2014.

  8. Statistical applications for chemistry, manufacturing and controls (CMC) in the pharmaceutical industry

    CERN Document Server

    Burdick, Richard K; Pfahler, Lori B; Quiroz, Jorge; Sidor, Leslie; Vukovinsky, Kimberly; Zhang, Lanju

    2017-01-01

    This book examines statistical techniques that are critically important to Chemistry, Manufacturing, and Control (CMC) activities. Statistical methods are presented with a focus on applications unique to the CMC in the pharmaceutical industry. The target audience consists of statisticians and other scientists who are responsible for performing statistical analyses within a CMC environment. Basic statistical concepts are addressed in Chapter 2 followed by applications to specific topics related to development and manufacturing. The mathematical level assumes an elementary understanding of statistical methods. The ability to use Excel or statistical packages such as Minitab, JMP, SAS, or R will provide more value to the reader. The motivation for this book came from an American Association of Pharmaceutical Scientists (AAPS) short course on statistical methods applied to CMC applications presented by four of the authors. One of the course participants asked us for a good reference book, and the only book recomm...

  9. 76 FR 34203 - Foreign-Trade Subzone 78A Application for Expansion of Manufacturing Authority Nissan North...

    Science.gov (United States)

    2011-06-13

    ... Application for Expansion of Manufacturing Authority Nissan North America, Inc. (Electric Passenger Vehicles... with authority granted for the manufacture of light-duty pickup trucks at the NNA plant located at 983...-1997). The applicant now seeks to expand the scope of authority to include electric-powered, light-duty...

  10. In Vitro Corrosion Assessment of Additively Manufactured Porous NiTi Structures for Bone Fixation Applications

    Directory of Open Access Journals (Sweden)

    Hamdy Ibrahim

    2018-03-01

    Full Text Available NiTi alloys possess distinct functional properties (i.e., shape memory effect and superelasticity and biocompatibility, making them appealing for bone fixation applications. Additive manufacturing offers an alternative method for fabricating NiTi parts, which are known to be very difficult to machine using conventional manufacturing methods. However, poor surface quality, and the presence of impurities and defects, are some of the major concerns associated with NiTi structures manufactured using additive manufacturing. The aim of this study is to assess the in vitro corrosion properties of additively manufactured NiTi structures. NiTi samples (bulk and porous were produced using selective laser melting (SLM, and their electrochemical corrosion characteristics and Ni ion release levels were measured and compared with conventionally fabricated NiTi parts. The additively manufactured NiTi structures were found to have electrochemical corrosion characteristics similar to those found for the conventionally fabricated NiTi alloy samples. The highest Ni ion release level was found in the case of 50% porous structures, which can be attributed to their significantly higher exposed surface area. However, the Ni ion release levels reported in this work for all the fabricated structures remain within the range of most of values for conventionally fabricated NiTi alloys reported in the literature. The results of this study suggest that the proposed SLM fabrication process does not result in a significant deterioration in the corrosion resistance of NiTi parts, making them suitable for bone fixation applications.

  11. Study of additive manufactured microwave cavities for pulsed optically pumped atomic clock applications

    Science.gov (United States)

    Affolderbach, C.; Moreno, W.; Ivanov, A. E.; Debogovic, T.; Pellaton, M.; Skrivervik, A. K.; de Rijk, E.; Mileti, G.

    2018-03-01

    Additive manufacturing (AM) of passive microwave components is of high interest for the cost-effective and rapid prototyping or manufacture of devices with complex geometries. Here, we present an experimental study on the properties of recently demonstrated microwave resonator cavities manufactured by AM, in view of their applications to high-performance compact atomic clocks. The microwave cavities employ a loop-gap geometry using six electrodes. The critical electrode structures were manufactured monolithically using two different approaches: Stereolithography (SLA) of a polymer followed by metal coating and Selective Laser Melting (SLM) of aluminum. The tested microwave cavities show the desired TE011-like resonant mode at the Rb clock frequency of ≈6.835 GHz, with a microwave magnetic field highly parallel to the quantization axis across the vapor cell. When operated in an atomic clock setup, the measured atomic Rabi oscillations are comparable to those observed for conventionally manufactured cavities and indicate a good uniformity of the field amplitude across the vapor cell. Employing a time-domain Ramsey scheme on one of the SLA cavities, high-contrast (34%) Ramsey fringes are observed for the Rb clock transition, along with a narrow (166 Hz linewidth) central fringe. The measured clock stability of 2.2 × 10-13 τ-1/2 up to the integration time of 30 s is comparable to the current state-of-the-art stabilities of compact vapor-cell clocks based on conventional microwave cavities and thus demonstrates the feasibility of the approach.

  12. Commercial grade item (CGI) dedication of generators for nuclear safety related applications

    International Nuclear Information System (INIS)

    Das, R.K.; Hajos, L.G.

    1993-01-01

    The number of nuclear safety related equipment suppliers and the availability of spare and replacement parts designed specifically for nuclear safety related application are shrinking rapidly. These have made it necessary for utilities to apply commercial grade spare and replacement parts in nuclear safety related applications after implementing proper acceptance and dedication process to verify that such items conform with the requirements of their use in nuclear safety related application. The general guidelines for the commercial grade item (CGI) acceptance and dedication are provided in US Nuclear Regulatory Commission (NRC) Generic Letters and Electric Power Research Institute (EPRI) Report NP-5652, Guideline for the Utilization of Commercial Grade Items in Nuclear Safety Related Applications. This paper presents an application of these generic guidelines for procurement, acceptance, and dedication of a commercial grade generator for use as a standby generator at Salem Generating Station Units 1 and 2. The paper identifies the critical characteristics of the generator which once verified, will provide reasonable assurance that the generator will perform its intended safety function. The paper also delineates the method of verification of the critical characteristics through tests and provide acceptance criteria for the test results. The methodology presented in this paper may be used as specific guidelines for reliable and cost effective procurement and dedication of commercial grade generators for use as standby generators at nuclear power plants

  13. 48 CFR 212.570 - Applicability of certain laws to contracts and subcontracts for the acquisition of commercially...

    Science.gov (United States)

    2010-10-01

    ..., DEPARTMENT OF DEFENSE ACQUISITION PLANNING ACQUISITION OF COMMERCIAL ITEMS Applicability of Certain Laws to the Acquisition of Commercial Items 212.570 Applicability of certain laws to contracts and... laws to contracts and subcontracts for the acquisition of commercially available off-the-shelf items...

  14. 48 CFR 212.503 - Applicability of certain laws to executive agency contracts for the acquisition of commercial items.

    Science.gov (United States)

    2010-10-01

    ... laws to executive agency contracts for the acquisition of commercial items. 212.503 Section 212.503... ACQUISITION PLANNING ACQUISITION OF COMMERCIAL ITEMS Applicability of Certain Laws to the Acquisition of Commercial Items 212.503 Applicability of certain laws to executive agency contracts for the acquisition of...

  15. Application, manufacturing and trends in development of nucleonic gauges in Poland

    International Nuclear Information System (INIS)

    Urbanski, P.

    1998-01-01

    The current status of manufacturing and application of radioisotope gauges in Poland is presented. Metrological performance of the gauges is briefly described and their expected feature prospects on the market of the industrial measuring instruments are discussed. Progress in electronic engineering and common use of the microprocessor systems in the radioisotope gauges made it possible the application of sophisticated methods of signal processing and data treatment, as for example statistical multivariate analysis. Some examples of the multivariate calibration of nucleonic gauges are presented. Application of the partial least square regression (PLS) and artificial neural network (ANN) for the calibration of gauges has been shown. (author)

  16. Application of Lean Manufacturing Tools in the Food and Beverage Industries

    Directory of Open Access Journals (Sweden)

    Rui Borges Lopes

    2015-10-01

    Full Text Available Recent years have shown an increasing use of lean manufacturing (LM principles and tools in several industrial sectors. Already a well-established management philosophy, it has shown numerous successful applications even outside production environments. This work presents the application of some LM tools, and the corresponding shift in philosophy, in two Portuguese companies of the food and beverage industries. Main implementation issues are presented and discussed; followed by the results obtained from the application of LM tools in the production system of these companies. Significant gains are obtained in both companies and, more importantly, it instills a continuous improvement culture and increases production flexibility while reducing lead times.

  17. 3D-Printed Chips: Compatibility of Additive Manufacturing Photopolymeric Substrata with Biological Applications

    Directory of Open Access Journals (Sweden)

    Megan Carve

    2018-02-01

    Full Text Available Additive manufacturing (AM is ideal for building adaptable, structurally complex, three-dimensional, monolithic lab-on-chip (LOC devices from only a computer design file. Consequently, it has potential to advance micro- to milllifluidic LOC design, prototyping, and production and further its application in areas of biomedical and biological research. However, its application in these areas has been hampered due to material biocompatibility concerns. In this review, we summarise commonly used AM techniques: vat polymerisation and material jetting. We discuss factors influencing material biocompatibility as well as methods to mitigate material toxicity and thus promote its application in these research fields.

  18. The application of virtual reality systems as a support of digital manufacturing and logistics

    Science.gov (United States)

    Golda, G.; Kampa, A.; Paprocka, I.

    2016-08-01

    Modern trends in development of computer aided techniques are heading toward the integration of design competitive products and so-called "digital manufacturing and logistics", supported by computer simulation software. All phases of product lifecycle: starting from design of a new product, through planning and control of manufacturing, assembly, internal logistics and repairs, quality control, distribution to customers and after-sale service, up to its recycling or utilization should be aided and managed by advanced packages of product lifecycle management software. Important problems for providing the efficient flow of materials in supply chain management of whole product lifecycle, using computer simulation will be described on that paper. Authors will pay attention to the processes of acquiring relevant information and correct data, necessary for virtual modeling and computer simulation of integrated manufacturing and logistics systems. The article describes possibilities of use an applications of virtual reality software for modeling and simulation the production and logistics processes in enterprise in different aspects of product lifecycle management. The authors demonstrate effective method of creating computer simulations for digital manufacturing and logistics and show modeled and programmed examples and solutions. They pay attention to development trends and show options of the applications that go beyond enterprise.

  19. The scope of additive manufacturing in cryogenics, component design, and applications

    Science.gov (United States)

    Stautner, W.; Vanapalli, S.; Weiss, K.-P.; Chen, R.; Amm, K.; Budesheim, E.; Ricci, J.

    2017-12-01

    Additive manufacturing techniques using composites or metals are rapidly gaining momentum in cryogenic applications. Small or large, complex structural components are now no longer limited to mere design studies but can now move into the production stream thanks to new machines on the market that allow for light-weight, cost optimized designs with short turnaround times. The potential for cost reductions from bulk materials machined to tight tolerances has become obvious. Furthermore, additive manufacturing opens doors and design space for cryogenic components that to date did not exist or were not possible in the past, using bulk materials along with elaborate and expensive machining processes, e.g. micromachining. The cryogenic engineer now faces the challenge to design toward those new additive manufacturing capabilities. Additionally, re-thinking designs toward cost optimization and fast implementation also requires detailed knowledge of mechanical and thermal properties at cryogenic temperatures. In the following we compile the information available to date and show a possible roadmap for additive manufacturing applications of parts and components typically used in cryogenic engineering designs.

  20. From design to manufacturing of asymmetric teeth gears using computer application

    Science.gov (United States)

    Suciu, F.; Dascalescu, A.; Ungureanu, M.

    2017-05-01

    The asymmetric cylindrical gears, with involutes teeth profiles having different base circle diameters, are nonstandard gears, used with the aim to obtain better function parameters for the active profile. We will expect that the manufacturing of these gears became possible only after the design and realization of some specific tools. The paper present how the computer aided design and applications developed in MATLAB, for obtain the geometrical parameters, in the same time for calculation some functional parameters like stress and displacements, transmission error, efficiency of the gears and the 2D models, generated with AUTOLISP applications, are used for computer aided manufacturing of asymmetric gears with standard tools. So the specific tools considered one of the disadvantages of these gears are not necessary and implicitly the expected supplementary costs are reduced. The calculus algorithm established for the asymmetric gear design application use the „direct design“ of the spur gears. This method offers the possibility of determining first the parameters of the gears, followed by the determination of the asymmetric gear rack’s parameters, based on those of the gears. Using original design method and computer applications have been determined the geometrical parameters, the 2D and 3D models of the asymmetric gears and on the base of these models have been manufacturing on CNC machine tool asymmetric gears.

  1. Country status of application, manufacturing and sterilization of single-use medical products

    International Nuclear Information System (INIS)

    Norimah Yusof

    1986-01-01

    The paper reviews the current status of application of single-use medical products in Malaysia. The status of their manufacturing and sterilization is also discussed. The increasing production of such items calls for a more reliable and efficient sterilization technique in particular, radiation sterilization. In line with the demand and the effort to increase local production of medical products, UTN would be providing irradiation service together with research and development in this particular field by 1988. (author)

  2. Evaluation of commercial and sulfated ZrO_2 aiming application catalysis

    International Nuclear Information System (INIS)

    Silva, F.N.; Dantas, J.; Costa, A.C.F.M.; Pallone, E.M.J.A.; Dutra, R.C.L.

    2014-01-01

    This study evaluates the performance of commercial and sulfated ZrO_2 for future application in catalysis. Commercial ZrO_2 was provided by the company Saint-Gobain Zirpro. The sulfation occurred with SO_4"-"2 ion content of 30% compared to the mass of ZrO_2. The samples were characterized by XRD, FTIR, EDX and GD. The results revealed the formation of a monoclinic phase for the commercial sample, and a monoclinic major phase with tetragonal traces for the sulfated sample. The commercial ZrO_2 showed a narrow, bimodal and asymmetric agglomerates distribution, while the sulfated sample showed a narrow, tetramodal and asymmetric agglomerates distribution. The presence of traces of the tetragonal phase in the SO_4"-"2/ZrO_2 XRD, and the presence of SO_3 in the EDX were good indicators for future use in catalysis to provide ester. (author)

  3. All-hexahedral meshing and remeshing for multi-object manufacturing applications

    DEFF Research Database (Denmark)

    Nielsen, Chris Valentin; Fernandes, J.L.M.; Martins, P.A.F.

    2013-01-01

    new developments related to the construction of adaptive core meshes and processing of multi-objects that are typical of manufacturing applications.Along with the aforementioned improvements there are other developments that will also be presented due to their effectiveness in increasing.......The presentation is enriched with examples taken from pure geometry and metal forming applications, and a resistance projection welding industrial test case consisting of four different objects is included to show the capabilities of selective remeshing of objects while maintaining contact conditions and local...

  4. A benchmark study of commercially available copper nanoparticle inks for application in organic electronic devices

    NARCIS (Netherlands)

    Polino, G.; Abbel, R.; Shanmugam, S.; Bex, G.J.P.; Hendriks, R.; Brunetti, F.; Di Carlo, A.; Andriessen, R.; Galagan, Y.

    2016-01-01

    A set of three commercial copper nanoparticle based inkjet inks has been benchmarked with respect to their potential to form conducting printed structures for future applications in organic electronic devices. Significant differences were observed in terms of jetting properties, spreading behaviour

  5. Technology Implementation Plan. Fully Ceramic Microencapsulated Fuel for Commercial Light Water Reactor Application

    International Nuclear Information System (INIS)

    Snead, Lance Lewis; Terrani, Kurt A.; Powers, Jeffrey J.; Worrall, Andrew; Robb, Kevin R.; Snead, Mary A.

    2015-01-01

    This report is an overview of the implementation plan for ORNL's fully ceramic microencapsulated (FCM) light water reactor fuel. The fully ceramic microencapsulated fuel consists of tristructural isotropic (TRISO) particles embedded inside a fully dense SiC matrix and is intended for utilization in commercial light water reactor application.

  6. Technology Implementation Plan. Fully Ceramic Microencapsulated Fuel for Commercial Light Water Reactor Application

    Energy Technology Data Exchange (ETDEWEB)

    Snead, Lance Lewis [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Terrani, Kurt A. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Powers, Jeffrey J. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Worrall, Andrew [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Robb, Kevin R. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Snead, Mary A. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States)

    2015-04-01

    This report is an overview of the implementation plan for ORNL's fully ceramic microencapsulated (FCM) light water reactor fuel. The fully ceramic microencapsulated fuel consists of tristructural isotropic (TRISO) particles embedded inside a fully dense SiC matrix and is intended for utilization in commercial light water reactor application.

  7. Manufacture of a heat-resistant alloy with modified specifications for HTGR structural applications

    International Nuclear Information System (INIS)

    Sahira, K.; Kondo, T.; Takeiri, T.

    1984-01-01

    A method of manufacturing a nuclear grade nickel-base heat-resistant alloy in application to heliumcooled reactor primary circuit components has been developed. The Hastelloy-XR alloy, a version of Hastelloy-X, was made available by combining the basic studies of the oxidation behavior of Hastelloy-X and the improvement of manufacturing techniques. In the primary and remelting steps, the choice of appropriate processes was made by performing numerical analyses of the statistical deviation of both chemical composition and the products' mechanical properties. The feasibility of making larger electroslag remelting ingots with reasonable control of macrosegregation was examined by the calculation of a molten metal pool shape during melting. The hot workability of Hastelloy-XR was confirmed to be equivalent to that of Hastelloy-X and the importance of controlling the thermal and mechanical processes more closely was stressed in obtaining a higher level of quality assurance for the nuclear applications. The possibility of enhancing the high-temperature mechanical performance of Hastelloy-XR was suggested based on the preliminary test results with the heats manufactured with controlled boron content

  8. Precision manufacturing

    CERN Document Server

    Dornfeld, David

    2008-01-01

    Today there is a high demand for high-precision products. The manufacturing processes are now highly sophisticated and derive from a specialized genre called precision engineering. Precision Manufacturing provides an introduction to precision engineering and manufacturing with an emphasis on the design and performance of precision machines and machine tools, metrology, tooling elements, machine structures, sources of error, precision machining processes and precision process planning. As well as discussing the critical role precision machine design for manufacturing has had in technological developments over the last few hundred years. In addition, the influence of sustainable manufacturing requirements in precision processes is introduced. Drawing upon years of practical experience and using numerous examples and illustrative applications, David Dornfeld and Dae-Eun Lee cover precision manufacturing as it applies to: The importance of measurement and metrology in the context of Precision Manufacturing. Th...

  9. Application of the iron-enriched basalt waste form for immobilizing commercial transuranic waste

    International Nuclear Information System (INIS)

    Owen, D.E.

    1981-08-01

    The principal sources of commercial transuranic (TRU) waste in the United States are identified. The physical and chemical nature of the wastes from these sources are discussed. The fabrication technique and properties of iron-enriched basalt, a rock-like waste form developed for immobilizing defense TRU wastes, are discussed. The application of iron-enriched basalt to commercial TRU wastes is discussed. Review of commercial TRU wastes from mixed-oxide fuel fabrication, light water reactor fuel reprocessing, and miscellaneous medical, research, and industrial sources, indicates that iron-enriched basalt is suitable for most types of commercial TRU wastes. Noncombustible TRU wastes are dissolved in the high temperature, oxidizing iron-enriched basalt melt. Combustible TRU wastes are immobilized in iron-enriched basalt by incinerating the wastes and adding the TRU-bearing ash to the melt. Casting and controlled cooling of the melt produces a devitrified, rock-like iron-enriched basalt monolith. Recommendations are given for testing the applicability of iron-enriched basalt to commercial TRU wastes

  10. New routes to the functionalization patterning and manufacture of graphene-based materials for biomedical applications.

    Science.gov (United States)

    De Sanctis, A; Russo, S; Craciun, M F; Alexeev, A; Barnes, M D; Nagareddy, V K; Wright, C D

    2018-06-06

    Graphene-based materials are being widely explored for a range of biomedical applications, from targeted drug delivery to biosensing, bioimaging and use for antibacterial treatments, to name but a few. In many such applications, it is not graphene itself that is used as the active agent, but one of its chemically functionalized forms. The type of chemical species used for functionalization will play a key role in determining the utility of any graphene-based device in any particular biomedical application, because this determines to a large part its physical, chemical, electrical and optical interactions. However, other factors will also be important in determining the eventual uptake of graphene-based biomedical technologies, in particular the ease and cost of manufacture of proposed device and system designs. In this work, we describe three novel routes for the chemical functionalization of graphene using oxygen, iron chloride and fluorine. We also introduce novel in situ methods for controlling and patterning such functionalization on the micro- and nanoscales. Our approaches are readily transferable to large-scale manufacturing, potentially paving the way for the eventual cost-effective production of functionalized graphene-based materials, devices and systems for a range of important biomedical applications.

  11. Robotics in space-age manufacturing

    Science.gov (United States)

    Jones, Chip

    1991-01-01

    Robotics technologies are developed to improve manufacturing of space hardware. The following applications of robotics are covered: (1) welding for the space shuttle and space station Freedom programs; (2) manipulation of high-pressure water for shuttle solid rocket booster refurbishment; (3) automating the application of insulation materials; (4) precision application of sealants; and (5) automation of inspection procedures. Commercial robots are used for these development programs, but they are teamed with advanced sensors, process controls, and computer simulation to form highly productive manufacturing systems. Many of the technologies are also being actively pursued in private sector manufacturing operations.

  12. ACE - Manufacturer Identification Code (MID)

    Data.gov (United States)

    Department of Homeland Security — The ACE Manufacturer Identification Code (MID) application is used to track and control identifications codes for manufacturers. A manufacturer is identified on an...

  13. Spectral imaging applications: Remote sensing, environmental monitoring, medicine, military operations, factory automation and manufacturing

    Energy Technology Data Exchange (ETDEWEB)

    Gat, N.; Subramanian, S. [Opto-Knowledge Systems, Inc. (United States); Barhen, J. [Oak Ridge National Lab., TN (United States); Toomarian, N. [Jet Propulsion Lab., Pasadena, CA (United States)

    1996-12-31

    This paper reviews the activities at OKSI related to imaging spectroscopy presenting current and future applications of the technology. The authors discuss the development of several systems including hardware, signal processing, data classification algorithms and benchmarking techniques to determine algorithm performance. Signal processing for each application is tailored by incorporating the phenomenology appropriate to the process, into the algorithms. Pixel signatures are classified using techniques such as principal component analyses, generalized eigenvalue analysis and novel very fast neural network methods. The major hyperspectral imaging systems developed at OKSI include the Intelligent Missile Seeker (IMS) demonstration project for real-time target/decoy discrimination, and the Thermal InfraRed Imaging Spectrometer (TIRIS) for detection and tracking of toxic plumes and gases. In addition, systems for applications in medical photodiagnosis, manufacturing technology, and for crop monitoring are also under development.

  14. The application of mechatronic design approach in a reconfigurable manufacturing environment

    CSIR Research Space (South Africa)

    Xing, B

    2010-12-01

    Full Text Available Manufacturing companies are faced with the challenge of unpredictable, high frequency market changes in both local and international markets. Two types of conventional manufacturing system: dedicated manufacturing system (DMS) and flexible...

  15. Aspects regarding manufacturing technologies of composite materials for brake pad application

    Science.gov (United States)

    Craciun, A. L.; Hepuţ, T.; Pinca-Bretotean, C.

    2018-01-01

    Current needs in road safety, requires the development of new technical solutions for automotive braking system. Their safe operation is subject to following factors: concept design, materials used and electronic control. Among the factors previously listed, choice of materials and manufacturing processes are difficult stage but very important for achieving technical performance and getting a relatively small cost of constituting parts of brake system. The choice is based on the promotion of organic composite material, popular in areas where the weight of materials plays an important role. The brake system is composed of many different parts including brake pads, a master cylinder, wheel cylinders and a hydraulic control system. The brake pads are an important component in the braking system of automotive. These are of different types, suitable for different types of automotive and engines. Brake pads are designed for friction stability, durability, minimization of noise and vibration. The typology of the brake pads depends on the material which they are made. The aim of this paper is to presents the manufacturing technologies for ten recipes of composite material used in brake pads applications. In this work will be done: choosing the constituents of the recipes, investigation of their basic characteristics, setting the proportions of components, obtaining the composite materials in laboratory, establishing the parameters of manufacturing technology and technological analysis.

  16. Metrology test object for dimensional verification in additive manufacturing of metals for biomedical applications.

    Science.gov (United States)

    Teeter, Matthew G; Kopacz, Alexander J; Nikolov, Hristo N; Holdsworth, David W

    2015-01-01

    Additive manufacturing continues to increase in popularity and is being used in applications such as biomaterial ingrowth that requires sub-millimeter dimensional accuracy. The purpose of this study was to design a metrology test object for determining the capabilities of additive manufacturing systems to produce common objects, with a focus on those relevant to medical applications. The test object was designed with a variety of features of varying dimensions, including holes, cylinders, rectangles, gaps, and lattices. The object was built using selective laser melting, and the produced dimensions were compared to the target dimensions. Location of the test objects on the build plate did not affect dimensions. Features with dimensions less than 0.300 mm did not build or were overbuilt to a minimum of 0.300 mm. The mean difference between target and measured dimensions was less than 0.100 mm in all cases. The test object is applicable to multiple systems and materials, tests the effect of location on the build, uses a minimum of material, and can be measured with a variety of efficient metrology tools (including measuring microscopes and micro-CT). Investigators can use this test object to determine the limits of systems and adjust build parameters to achieve maximum accuracy. © IMechE 2014.

  17. Additive manufacturing of titanium alloys in the biomedical field: processes, properties and applications.

    Science.gov (United States)

    Trevisan, Francesco; Calignano, Flaviana; Aversa, Alberta; Marchese, Giulio; Lombardi, Mariangela; Biamino, Sara; Ugues, Daniele; Manfredi, Diego

    2018-04-01

    The mechanical properties and biocompatibility of titanium alloy medical devices and implants produced by additive manufacturing (AM) technologies - in particular, selective laser melting (SLM), electron beam melting (EBM) and laser metal deposition (LMD) - have been investigated by several researchers demonstrating how these innovative processes are able to fulfil medical requirements for clinical applications. This work reviews the advantages given by these technologies, which include the possibility to create porous complex structures to improve osseointegration and mechanical properties (best match with the modulus of elasticity of local bone), to lower processing costs, to produce custom-made implants according to the data for the patient acquired via computed tomography and to reduce waste.

  18. The application of TIG-welding to the manufacture of modern boiler units. Chapter 3

    International Nuclear Information System (INIS)

    Dick, N.T.

    1978-01-01

    Stringent weld acceptance standards are necessary in nuclear installations. Mechanised TIG-welding is being used exclusively in the manufacture of the boiler pods for the Hartlepool and Heysham nuclear generating stations. The choice of a TIG welding process is discussed. Reliability, access, welding position, tube dimensions and weld profile were important as was the desirability of having ferrite control because in the austenitic stainless steel used, the acceptance standard does not permit microfissuring. Development of the technique and production equipment and conditions are given for tube butt welding, tube-to-tubeplate bore welding and tube-to-tubeplate face welding in AGR applications. (U.K.)

  19. PROSPECTS OF APPLICATION OF THE CONCEPTOF QUICK RESPONSE MANUFACTURING AT THE RUSSIAN INDUSTRIAL ENTERPRISES

    Directory of Open Access Journals (Sweden)

    Ch. V. Shipilova

    2016-01-01

    Full Text Available This article is devoted to research of such concept of the organization of production, as Quick Response Manufacturing or Quick-response production, at the center which, time of implementation of the order is put. Today domestic producers are compelled to function in new conditions, competing with a great number of players of the global market, as a result the emphasis on timely implementation of orders and a tendency of reduction of time of production will allow to reach competitive advantages. Fundamental aspects of Quick Response Manufacturing within functioning of the enterprise of branch are considered, and also the essential lack of this concept is revealed.The purpose / objectives. The purpose of article is research of the economic contents of the concept of the organization of production Quick Response Manufacturing and area of its use at the modern industrial enterprises. Article tasks: to investigate economic contents of the concept of Quick Response Manufacturing, to reveal its features and scopes in the modern industry.Methods. A methodical basis of this article are comparative methods of the analysis.Results. The economic contents of the concept of Quick Response Manufacturing are investigated. Four main key aspects which are the cornerstone of this concept are investigated: time force, organizational structure of the enterprise, system dynamics and possibilities of its application in scales of all enterprise. Components of positive work of system dynamics of the industrial enterprise are revealed, the trend of critical process of production is built. Considering that modern conditions demand from the enterprises to react, adapt quickly for the changing conditions, the factor of time plays an important role. Therefore the concept of QRM has rather perspective character, focusing attention on time of implementation of the order, in that communication that this parameter is one of key both for the enterprise, and for increase of its

  20. Application of secondary ion mass spectrometry for the characterization of commercial high performance materials

    International Nuclear Information System (INIS)

    Gritsch, M.

    2000-09-01

    The industry today offers an uncounted number of high performance materials, that have to meet highest standards. Commercial high performance materials, though often sold in large quantities, still require ongoing research and development to keep up to date with increasing needs and decreasing tolerances. Furthermore, a variety of materials is on the market that are not fully understood in their microstructure, in the way they react under application conditions, and in which mechanisms are responsible for their degradation. Secondary Ion Mass Spectrometry (SIMS) is an analytical method that is now in commercial use for over 30 years. Its main advantages are the very high detection sensitivity (down to ppb), the ability to measure all elements with isotopic sensitivity, the ability of gaining laterally resolved images, and the inherent capability of depth-profiling. These features make it an ideal tool for a wide field of applications within advanced material science. The present work gives an introduction into the principles of SIMS and shows the successful application for the characterization of commercially used high performance materials. Finally, a selected collection of my publications in reviewed journals will illustrate the state of the art in applied materials research and development with dynamic SIMS. All publications focus on the application of dynamic SIMS to analytical questions that stem from questions arising during the production and improvement of high-performance materials. (author)

  1. High-energy radiation and polymers: A review of commercial processes and emerging applications

    International Nuclear Information System (INIS)

    Clough, R.L.

    2001-01-01

    Ionizing radiation has been found to be widely applicable in modifying the structure and properties of polymers, and can be used to tailor the performance of either bulk materials or surfaces. Fifty years of research in polymer radiation chemistry has led to numerous applications of commercial and economic importance, and work remains active in the application of radiation to practical uses involving polymeric materials. This paper provides a survey of radiation-processing methods of industrial interest, ranging from technologies already commercially well established, through innovations in the active R and D stage which show exceptional promise for future commercial use. Radiation-processing technologies are discussed under the following categories: cross-linking of plastics and rubbers, curing of coatings and inks, heat-shrink products, fiber-matrix composites, chain-scission for processing control, surface modification, grafting, hydrogels, sterilization, natural product enhancement, plastics recycling, ceramic precursors, electronic property materials, ion-track membranes and lithography for microdevice production. In addition to new technological innovations utilizing conventional gamma and e-beam sources, a number of promising new applications make use of novel radiation types which include ion beams (heavy ions, light ions, highly focused microscopic beams and high-intensity pulses), soft X-rays which are focused, coherent X-rays (from a synchrotron) and e-beams which undergo scattering to generate patterns

  2. Application of IC Card License for Road Transportation in Commercial Vehicles Supervision and Service

    Directory of Open Access Journals (Sweden)

    Li Weiwei

    2016-01-01

    Full Text Available IC card electronic license for road transport includes the IC card commercial vehicle’s certificate and IC card practitioner’s qualification certificate. In China, the IC card electronic license for road transport is the electronic ID card which must be carried by each commercial vehicles and practitioners. This paper briefly introduces the basic situation, data format and security keys architecture of IC card electronic license for road transportation of China. In order to strengthen the supervision and service of commercial vehicles, this paper puts forward the overall application framework of IC card electronic license for road transport. The application examples of IC card license in the supervision of passenger station, dangerous goods transport management, governance overload and logistics park and port area management are discussed. The practical application results show that the application of IC card electronic license for road transport is an important technical means to improve the supervision ability and service quality of the road transportation industry.

  3. Trends in genetic patent applications: the commercialization of academic intellectual property.

    Science.gov (United States)

    Kers, Jannigje G; Van Burg, Elco; Stoop, Tom; Cornel, Martina C

    2014-10-01

    We studied trends in genetic patent applications in order to identify the trends in the commercialization of research findings in genetics. To define genetic patent applications, the European version (ECLA) of the International Patent Classification (IPC) codes was used. Genetic patent applications data from the PATSTAT database from 1990 until 2009 were analyzed for time trends and regional distribution. Overall, the number of patent applications has been growing. In 2009, 152 000 patent applications were submitted under the Patent Cooperation Treaty (PCT) and within the EP (European Patent) system of the European Patent Office (EPO). The number of genetic patent applications increased until a peak was reached in the year 2000, with >8000 applications, after which it declined by almost 50%. Continents show different patterns over time, with the global peak in 2000 mainly explained by the USA and Europe, while Asia shows a stable number of >1000 per year. Nine countries together account for 98.9% of the total number of genetic patent applications. In The Netherlands, 26.7% of the genetic patent applications originate from public research institutions. After the year 2000, the number of genetic patent applications dropped significantly. Academic leadership and policy as well as patent regulations seem to have an important role in the trend differences. The ongoing investment in genetic research in the past decade is not reflected by an increase of patent applications.

  4. Development and Hotfire Testing of Additively Manufactured Copper Combustion Chambers for Liquid Rocket Engine Applications

    Science.gov (United States)

    Gradl, Paul R.; Greene, Sandy; Protz, Chris

    2017-01-01

    NASA and industry partners are working towards fabrication process development to reduce costs and schedules associated with manufacturing liquid rocket engine components with the goal of reducing overall mission costs. One such technique being evaluated is powder-bed fusion or selective laser melting (SLM), commonly referred to as additive manufacturing (AM). The NASA Low Cost Upper Stage Propulsion (LCUSP) program was designed to develop processes and material characterization for GRCop-84 (a NASA Glenn Research Center-developed copper, chrome, niobium alloy) commensurate with powder bed AM, evaluate bimetallic deposition, and complete testing of a full scale combustion chamber. As part of this development, the process has been transferred to industry partners to enable a long-term supply chain of monolithic copper combustion chambers. To advance the processes further and allow for optimization with multiple materials, NASA is also investigating the feasibility of bimetallic AM chambers. In addition to the LCUSP program, NASA’s Marshall Space Flight Center (MSFC) has completed a series of development programs and hot-fire tests to demonstrate SLM GRCop-84 and other AM techniques. MSFC’s efforts include a 4,000 pounds-force thrust liquid oxygen/methane (LOX/CH4) combustion chamber. Small thrust chambers for 1,200 pounds-force LOX/hydrogen (H2) applications have also been designed and fabricated with SLM GRCop-84. Similar chambers have also completed development with an Inconel 625 jacket bonded to the GRCop-84 material, evaluating direct metal deposition (DMD) laser- and arc-based techniques. The same technologies for these lower thrust applications are being applied to 25,000-35,000 pounds-force main combustion chamber (MCC) designs. This paper describes the design, development, manufacturing and testing of these numerous combustion chambers, and the associated lessons learned throughout their design and development processes.

  5. Grain Refinement of Commercial EC Grade 1070 Aluminium Alloy for Electrical Application

    OpenAIRE

    Hassanabadi, Massoud

    2015-01-01

    The aluminium alloys for electrical conductivity applications are generally not grain refinedsince the addition of grain refiners drops the electrical conductivity by introducing impuritiesinto the melt. Non-grain refined aluminium may lead to bar fracture and cracks during themetalworking process. The present study focuses to find an optimum balance between the grain refiner addition andthe electrical conductivity of commercial EC grade 1070 aluminium alloy for electricalapplication. In orde...

  6. Wafer-level micro-optics: trends in manufacturing, testing, packaging, and applications

    Science.gov (United States)

    Voelkel, Reinhard; Gong, Li; Rieck, Juergen; Zheng, Alan

    2012-11-01

    Micro-optics is an indispensable key enabling technology (KET) for many products and applications today. Probably the most prestigious examples are the diffractive light shaping elements used in high-end DUV lithography steppers. Highly efficient refractive and diffractive micro-optical elements are used for precise beam and pupil shaping. Micro-optics had a major impact on the reduction of aberrations and diffraction effects in projection lithography, allowing a resolution enhancement from 250 nm to 45 nm within the last decade. Micro-optics also plays a decisive role in medical devices (endoscopes, ophthalmology), in all laser-based devices and fiber communication networks (supercomputer, ROADM), bringing high-speed internet to our homes (FTTH). Even our modern smart phones contain a variety of micro-optical elements. For example, LED flashlight shaping elements, the secondary camera, and ambient light and proximity sensors. Wherever light is involved, micro-optics offers the chance to further miniaturize a device, to improve its performance, or to reduce manufacturing and packaging costs. Wafer-scale micro-optics fabrication is based on technology established by semiconductor industry. Thousands of components are fabricated in parallel on a wafer. We report on the state of the art in wafer-based manufacturing, testing, packaging and present examples and applications for micro-optical components and systems.

  7. Atomic layer deposition for photovoltaics: applications and prospects for solar cell manufacturing

    International Nuclear Information System (INIS)

    Van Delft, J A; Garcia-Alonso, D; Kessels, W M M

    2012-01-01

    Atomic layer deposition (ALD) is a vapour-phase deposition technique capable of depositing high quality, uniform and conformal thin films at relatively low temperatures. These outstanding properties can be employed to face processing challenges for various types of next-generation solar cells; hence, ALD for photovoltaics (PV) has attracted great interest in academic and industrial research in recent years. In this review, the recent progress of ALD layers applied to various solar cell concepts and their future prospects are discussed. Crystalline silicon (c-Si), copper indium gallium selenide (CIGS) and dye-sensitized solar cells (DSSCs) benefit from the application of ALD surface passivation layers, buffer layers and barrier layers, respectively. ALD films are also excellent moisture permeation barriers that have been successfully used to encapsulate flexible CIGS and organic photovoltaic (OPV) cells. Furthermore, some emerging applications of the ALD method in solar cell research are reviewed. The potential of ALD for solar cells manufacturing is discussed, and the current status of high-throughput ALD equipment development is presented. ALD is on the verge of being introduced in the PV industry and it is expected that it will be part of the standard solar cell manufacturing equipment in the near future. (paper)

  8. Application of magnetic resonance imaging and spectroscopy in studying the biological effects of manufactured nanoparticles

    International Nuclear Information System (INIS)

    Lei Hao; Wei Li; Liu Maili

    2006-01-01

    With the rapid development of nanoscience and nanotechnology in recent years, growing research interest and efforts have been directed to study the biological effects of manufactured nanoparticles and substances alike. Despite the fact that significant progress has been made, this is still largely an uncharted field. Any advances in this field would certainly require thorough multi-disciplinary collaboration, in which the expertise and tools in nanoscience/nanotechnoloogy, physics, chemistry and biomedicine have to be combined. Due to their wide range of applications in physics, chemistry and biomedicine, magnetic resonance (MR) imaging and spectroscopy are among the most important and powerful research tools currently in use, mainly because these techniques can be used in situ and noninvasively to acquire dynamic and real-time information in various samples ranging from protein solution to the human brain. In this paper, the application of MR imaging and spectroscopy in studying the biological effects of manufactured nanoparticles is discussed. It is expected that these techniques will play important roles in 1) detecting the presence of nanoparticles in biological tissues and in vivo, 2) studying the interactions between the nanoparticles and biomolecules and 3) investigating the metabonomic aspect of the biological effects of nanoparticles. (authors)

  9. Application of lean manufacturing concepts to drug discovery: rapid analogue library synthesis.

    Science.gov (United States)

    Weller, Harold N; Nirschl, David S; Petrillo, Edward W; Poss, Michael A; Andres, Charles J; Cavallaro, Cullen L; Echols, Martin M; Grant-Young, Katherine A; Houston, John G; Miller, Arthur V; Swann, R Thomas

    2006-01-01

    The application of parallel synthesis to lead optimization programs in drug discovery has been an ongoing challenge since the first reports of library synthesis. A number of approaches to the application of parallel array synthesis to lead optimization have been attempted over the years, ranging from widespread deployment by (and support of) individual medicinal chemists to centralization as a service by an expert core team. This manuscript describes our experience with the latter approach, which was undertaken as part of a larger initiative to optimize drug discovery. In particular, we highlight how concepts taken from the manufacturing sector can be applied to drug discovery and parallel synthesis to improve the timeliness and thus the impact of arrays on drug discovery.

  10. Precision ring rolling technique and application in high-performance bearing manufacturing

    Directory of Open Access Journals (Sweden)

    Hua Lin

    2015-01-01

    Full Text Available High-performance bearing has significant application in many important industry fields, like automobile, precision machine tool, wind power, etc. Precision ring rolling is an advanced rotary forming technique to manufacture high-performance seamless bearing ring thus can improve the working life of bearing. In this paper, three kinds of precision ring rolling techniques adapt to different dimensional ranges of bearings are introduced, which are cold ring rolling for small-scale bearing, hot radial ring rolling for medium-scale bearing and hot radial-axial ring rolling for large-scale bearing. The forming principles, technological features and forming equipments for three kinds of precision ring rolling techniques are summarized, the technological development and industrial application in China are introduced, and the main technological development trend is described.

  11. Internal frictions and their application in the supervision and inspection of a manufacture

    International Nuclear Information System (INIS)

    Bourgain, L.; Samson, G.; Blay, D.

    1975-01-01

    The internal frictions of materials subjected to flexion or compression waves were studied. In the first part of the report, devoted to the theoretical aspect of the problem, an attempt is made to estimate how much of the total friction measured is exterior to the structure and how much is intrinsic. The mathematical models generally used to account for these phenomena, those of Maxwell and Voigt, were applied for this purpose. Part two deals with measurement methods and precautions necessary if good precision and reproducible experimental results are required. The last part gives several examples of application. It is shown how internal damping measurements are used to detect variations in a given manufacture. In the application specific to sintered materials a physical explanation is tentatively put forward to account for the peaks recorded at middle frequency (between 1000 and 10000 hertz) in the damping spectrum; these are connected with interface phenomena between the grains, sometimes known as surface/volume effect [fr

  12. The combined application of PIXE analysis and thermoluminescence (TL) dating for elucidating the origin of iron manufacturing in Japan

    International Nuclear Information System (INIS)

    Hagihara, N.; Miono, S.; Chengzhi, Z.; Nakayama, Y.; Hanamoto, K.; Manabe, S.

    1999-01-01

    For elucidating the origin of iron manufacturing in Japan, the usefulness of PIXE analysis was reconfirmed and a new technique of thermoluminescence (TL) dating was applied. Through reproducing experiments of iron manufacturing and forging, PIXE analysis was tested for classifying the iron slag produced from these two different process. The TL dating method was improved for experiments with the iron manufacturing furnace, burnt at high temperature (about 1300 K) and irradiated with relatively low dose. Utilizing PIXE analysis, the iron manufacturing furnace can be distinguished from the older forging furnace used for the imported iron plate. Adopting TL dating, the oldest iron manufacturing furnace can be found out. Some ancient samples in Japan were used as a test of this combined application, and the results were positive, thus proving the suitability of the method

  13. APPLICATION OF FORMS AND METHODS OF COMMERCIALIZATION OF INNOVATIONS THROUGH THE INTERACTION OF UNIVERSITIES AND ENTERPRISES

    Directory of Open Access Journals (Sweden)

    Svetlana E. Sitnikova

    2018-03-01

    Full Text Available In the conditions of formation of economy based on knowledge, a key condition for successful development is the effective integration of science, education and business. Currently, the commercialization of innovation becomes a necessary factor for sustainable development of universities, one of their main tools to increase its competitiveness in the market of educational services and products. The efficiency of the process of innovation commercialization is conditioned by the rational choice of forms and methods of implementing this process. The interaction of universities and enterprises in the innovative clusters provides benefits such as effective dissemination of information about the creation of innovations, the relevant areas of research, the granting of preferences to cluster participants. The creation of technoparks suggests the presence of a specially allocated site, which houses many new businesses, so that existing institutions can only be partners of the technopark. From the point of view of commercialization of University innovation, the cluster seems to be a more attractive method compared with the creation of technology parks, but its application is necessary to adjust the approach to conducting the state policy in the field of innovation management. The interaction of universities and enterprises via an intermediary – the chamber of commerce and industry – can be described as an obstacle to the commercialization of university innovations. On the contrary, technological innovation center protects the interests of universities, rather than enterprises, as it is created to facilitate the commercialization of university innovation. Direct interaction of universities and enterprises becomes possible with the help of methods of a single transaction, a regular cooperation and a contract for the supply of innovation. The choice of methods of commercialization of innovations should be made on the basis of existing university

  14. Application of narrow-band television to industrial and commercial communications

    Science.gov (United States)

    Embrey, B. C., Jr.; Southworth, G. R.

    1974-01-01

    The development of narrow-band systems for use in space systems is presented. Applications of the technology to future spacecraft requirements are discussed along with narrow-band television's influence in stimulating development within the industry. The transferral of the technology into industrial and commercial communications is described. Major areas included are: (1) medicine; (2) education; (3) remote sensing for traffic control; and (5) weather observation. Applications in data processing, image enhancement, and information retrieval are provided by the combination of the TV camera and the computer.

  15. 40 CFR 725.190 - Notice of commencement of manufacture or import.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 30 2010-07-01 2010-07-01 false Notice of commencement of manufacture... Microbial Commercial Activities Notification Requirements § 725.190 Notice of commencement of manufacture or import. (a) Applicability. Any person who commences the manufacture or import of a new microorganism for...

  16. Gas-cooled reactor commercialization study: introduction scenario and commercialization analyses for process heat applications. Final report, July 8, 1977--November 30, 1977

    International Nuclear Information System (INIS)

    1977-12-01

    This report identifies and presents an introduction scenario which can lead to the operation of High Temperature Gas Cooled Reactor demonstration plants for combined process heat and electric power generation applications, and presents a commercialization analysis relevant to the organizational and management plans which could implement a development program

  17. Gas-cooled reactor commercialization study: introduction scenario and commercialization analyses for process heat applications. Final report, July 8, 1977--November 30, 1977

    Energy Technology Data Exchange (ETDEWEB)

    1977-12-01

    This report identifies and presents an introduction scenario which can lead to the operation of High Temperature Gas Cooled Reactor demonstration plants for combined process heat and electric power generation applications, and presents a commercialization analysis relevant to the organizational and management plans which could implement a development program.

  18. Application of quality by design principles to the development and technology transfer of a major process improvement for the manufacture of a recombinant protein.

    Science.gov (United States)

    Looby, Mairead; Ibarra, Neysi; Pierce, James J; Buckley, Kevin; O'Donovan, Eimear; Heenan, Mary; Moran, Enda; Farid, Suzanne S; Baganz, Frank

    2011-01-01

    This study describes the application of quality by design (QbD) principles to the development and implementation of a major manufacturing process improvement for a commercially distributed therapeutic protein produced in Chinese hamster ovary cell culture. The intent of this article is to focus on QbD concepts, and provide guidance and understanding on how the various components combine together to deliver a robust process in keeping with the principles of QbD. A fed-batch production culture and a virus inactivation step are described as representative examples of upstream and downstream unit operations that were characterized. A systematic approach incorporating QbD principles was applied to both unit operations, involving risk assessment of potential process failure points, small-scale model qualification, design and execution of experiments, definition of operating parameter ranges and process validation acceptance criteria followed by manufacturing-scale implementation and process validation. Statistical experimental designs were applied to the execution of process characterization studies evaluating the impact of operating parameters on product quality attributes and process performance parameters. Data from process characterization experiments were used to define the proven acceptable range and classification of operating parameters for each unit operation. Analysis of variance and Monte Carlo simulation methods were used to assess the appropriateness of process design spaces. Successful implementation and validation of the process in the manufacturing facility and the subsequent manufacture of hundreds of batches of this therapeutic protein verifies the approaches taken as a suitable model for the development, scale-up and operation of any biopharmaceutical manufacturing process. Copyright © 2011 American Institute of Chemical Engineers (AIChE).

  19. Mobile clinical decision support systems and applications: a literature and commercial review.

    Science.gov (United States)

    Martínez-Pérez, Borja; de la Torre-Díez, Isabel; López-Coronado, Miguel; Sainz-de-Abajo, Beatriz; Robles, Montserrat; García-Gómez, Juan Miguel

    2014-01-01

    The latest advances in eHealth and mHealth have propitiated the rapidly creation and expansion of mobile applications for health care. One of these types of applications are the clinical decision support systems, which nowadays are being implemented in mobile apps to facilitate the access to health care professionals in their daily clinical decisions. The aim of this paper is twofold. Firstly, to make a review of the current systems available in the literature and in commercial stores. Secondly, to analyze a sample of applications in order to obtain some conclusions and recommendations. Two reviews have been done: a literature review on Scopus, IEEE Xplore, Web of Knowledge and PubMed and a commercial review on Google play and the App Store. Five applications from each review have been selected to develop an in-depth analysis and to obtain more information about the mobile clinical decision support systems. Ninety-two relevant papers and 192 commercial apps were found. Forty-four papers were focused only on mobile clinical decision support systems. One hundred seventy-one apps were available on Google play and 21 on the App Store. The apps are designed for general medicine and 37 different specialties, with some features common in all of them despite of the different medical fields objective. The number of mobile clinical decision support applications and their inclusion in clinical practices has risen in the last years. However, developers must be careful with their interface or the easiness of use, which can impoverish the experience of the users.

  20. 77 FR 68102 - Foreign-Trade Zone 163-Ponce, PR; Application for Subzone; Zimmer Manufacturing BV; Ponce, PR

    Science.gov (United States)

    2012-11-15

    ... DEPARTMENT OF COMMERCE Foreign-Trade Zones Board [B-81-2012] Foreign-Trade Zone 163--Ponce, PR; Application for Subzone; Zimmer Manufacturing BV; Ponce, PR An application has been submitted to the Foreign-Trade Zones Board (the Board) by CODEZOL, C.D., grantee of FTZ 163, requesting special- purpose subzone...

  1. Can surveillance systems identify and avert adverse drug events? A prospective evaluation of a commercial application.

    Science.gov (United States)

    Jha, Ashish K; Laguette, Julia; Seger, Andrew; Bates, David W

    2008-01-01

    Computerized monitors can effectively detect and potentially prevent adverse drug events (ADEs). Most monitors have been developed in large academic hospitals and are not readily usable in other settings. We assessed the ability of a commercial program to identify and prevent ADEs in a community hospital. and Measurement We prospectively evaluated the commercial application in a community-based hospital. We examined the frequency and types of alerts produced, how often they were associated with ADEs and potential ADEs, and the potential financial impact of monitoring for ADEs. Among 2,407 patients screened, the application generated 516 high priority alerts. We were able to review 266 alerts at the time they were generated and among these, 30 (11.3%) were considered substantially important to warrant contacting the physician caring for the patient. These 30 alerts were associated with 4 ADEs and 11 potential ADEs. In all 15 cases, the responsible physician was unaware of the event, leading to a change in clinical care in 14 cases. Overall, 23% of high priority alerts were associated with an ADE (95% confidence interval [CI] 12% to 34%) and another 15% were associated with a potential ADE (95% CI 6% to 24%). Active surveillance used approximately 1.5 hours of pharmacist time daily. A commercially available, computer-based ADE detection tool was effective at identifying ADEs. When used as part of an active surveillance program, it can have an impact on preventing or ameliorating ADEs.

  2. Technical meeting on commercial applications of nuclear analytical techniques. Meeting report

    International Nuclear Information System (INIS)

    2004-01-01

    This report summarizes the findings of the Technical Meeting on the Commercial Applications of Nuclear Analytical Techniques held in Vienna on 23-26 November 2004, where an assessment was initiated of the world capacity and market potentials for neutron activation analysis and nuclear spectroscopy, including an estimation of economic revenues. Industry and governmental agencies were identified as stakeholders for these laboratories. Examples are given of potential benefits of these techniques to the stakeholders. The potentials for commercial applications of neutron activation analysis and nuclear spectroscopy (measurement of alpha, beta and gamma ray emitting radionuclides) are addressed. First estimates are given of the worldwide capacity of these laboratories, suggestions and examples are given for potential markets and the typical organizational and technical constraints are discussed. Two case studies of commercial neutron activation analysis laboratories at a small and a medium-size reactor are given in the 'individual contributions' section of this document. An assessment of other nuclear analytical techniques such as X ray Fluorescence Spectrometry, Particle Induced X ray Emission Spectrometry or Ion Beam Analysis Spectrometry has been completed after a comprehensive collection of background information

  3. Technical meeting on commercial applications of nuclear analytical techniques. Meeting report

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2004-07-01

    This report summarizes the findings of the Technical Meeting on the Commercial Applications of Nuclear Analytical Techniques held in Vienna on 23-26 November 2004, where an assessment was initiated of the world capacity and market potentials for neutron activation analysis and nuclear spectroscopy, including an estimation of economic revenues. Industry and governmental agencies were identified as stakeholders for these laboratories. Examples are given of potential benefits of these techniques to the stakeholders. The potentials for commercial applications of neutron activation analysis and nuclear spectroscopy (measurement of alpha, beta and gamma ray emitting radionuclides) are addressed. First estimates are given of the worldwide capacity of these laboratories, suggestions and examples are given for potential markets and the typical organizational and technical constraints are discussed. Two case studies of commercial neutron activation analysis laboratories at a small and a medium-size reactor are given in the 'individual contributions' section of this document. An assessment of other nuclear analytical techniques such as X ray Fluorescence Spectrometry, Particle Induced X ray Emission Spectrometry or Ion Beam Analysis Spectrometry has been completed after a comprehensive collection of background information.

  4. Labour standards application among multinational and domestic firms in Ghana’s manufacturing sector

    Directory of Open Access Journals (Sweden)

    Dziedzom-Akorsu Angela

    2011-01-01

    Full Text Available This paper provides an empirical analysis of the labour standards application patterns and influences among multinational and domestic firms in Ghana. Discourses on labour standards application have continued to attract much interest in recent years. This is because globalization, in tandem with multinational corporations, has made the application of labour standards more challenging and ever more relevant. Yet competing viewpoints raised among social scientists on the subject are inconclusive and still on-going. While some are of the view that multinational companies (MNCs maintain higher labour standards than the domestic firms of their host countries, others concede that their standards are lower due to their exploitative tendencies. By means of a survey of 248 multinational and domestic firms in the manufacturing sector of Ghana, this paper concludes that there are a number of contingent factors that determine labour standards application, and so it is misleading to put all firms together and make blanket statements as to whether or not one group maintains higher labour standards than the other.

  5. Recent developments in turbomachinery component materials and manufacturing challenges for aero engine applications

    Science.gov (United States)

    Srinivas, G.; Raghunandana, K.; Satish Shenoy, B.

    2018-02-01

    In the recent years the development of turbomachinery materials performance enhancement plays a vital role especially in aircraft air breathing engines like turbojet engine, turboprop engine, turboshaft engine and turbofan engines. Especially the transonic flow engines required highly sophisticated materials where it can sustain the entire thrust which can create by the engine. The main objective of this paper is to give an overview of the present cost-effective and technological capabilities process for turbomachinery component materials. Especially the main focus is given to study the Electro physical, Photonic additive removal process and Electro chemical process for turbomachinery parts manufacture. The aeronautical propulsion based technologies are reviewed thoroughly where in surface reliability, geometrical precession, and material removal and highly strengthened composite material deposition rates usually difficult to cut dedicated steels, Titanium and Nickel based alloys. In this paper the past aeronautical and propulsion mechanical based manufacturing technologies, current sophisticated technologies and also future challenging material processing techniques are covered. The paper also focuses on the brief description of turbomachinery components of shaping process and coating in aeromechanical applications.

  6. Quality by design approach: application of artificial intelligence techniques of tablets manufactured by direct compression.

    Science.gov (United States)

    Aksu, Buket; Paradkar, Anant; de Matas, Marcel; Ozer, Ozgen; Güneri, Tamer; York, Peter

    2012-12-01

    The publication of the International Conference of Harmonization (ICH) Q8, Q9, and Q10 guidelines paved the way for the standardization of quality after the Food and Drug Administration issued current Good Manufacturing Practices guidelines in 2003. "Quality by Design", mentioned in the ICH Q8 guideline, offers a better scientific understanding of critical process and product qualities using knowledge obtained during the life cycle of a product. In this scope, the "knowledge space" is a summary of all process knowledge obtained during product development, and the "design space" is the area in which a product can be manufactured within acceptable limits. To create the spaces, artificial neural networks (ANNs) can be used to emphasize the multidimensional interactions of input variables and to closely bind these variables to a design space. This helps guide the experimental design process to include interactions among the input variables, along with modeling and optimization of pharmaceutical formulations. The objective of this study was to develop an integrated multivariate approach to obtain a quality product based on an understanding of the cause-effect relationships between formulation ingredients and product properties with ANNs and genetic programming on the ramipril tablets prepared by the direct compression method. In this study, the data are generated through the systematic application of the design of experiments (DoE) principles and optimization studies using artificial neural networks and neurofuzzy logic programs.

  7. Innovation leading the way: application of lean manufacturing to sample management.

    Science.gov (United States)

    Allen, M; Wigglesworth, M J

    2009-06-01

    Historically, sample management successfully focused on providing compound quality and tracking distribution within a diverse geographic. However, if a competitive advantage is to be delivered in a changing environment of outsourcing, efficiency and customer service must now improve or face reconstruction. The authors have used discrete event simulation to model the compound process from chemistry to assay and applied lean manufacturing techniques to analyze and improve these processes. In doing so, they identified a value-adding process time of just 11 min within a procedure that took days. Modeling also allowed the analysis of equipment and human resources necessary to complete the expected demand in an acceptable cycle time. Layout and location of sample management and screening departments are key in allowing process integration, creating rapid flow of work, and delivering these efficiencies. Following this analysis and minor process changes, the authors have demonstrated for 2 programs that solid compounds can be converted to assay-ready plates in less than 4 h. In addition, it is now possible to deliver assay data from these compounds within the same working day, allowing chemistry teams more flexibility and more time to execute the next chemistry round. Additional application of lean manufacturing principles has the potential to further decrease cycle times while using fewer resources.

  8. Application of the threshold of toxicological concern concept to pharmaceutical manufacturing operations.

    Science.gov (United States)

    Dolan, David G; Naumann, Bruce D; Sargent, Edward V; Maier, Andrew; Dourson, Michael

    2005-10-01

    A scientific rationale is provided for estimating acceptable daily intake values (ADIs) for compounds with limited or no toxicity information to support pharmaceutical manufacturing operations. These ADIs are based on application of the "thresholds of toxicological concern" (TTC) principle, in which levels of human exposure are estimated that pose no appreciable risk to human health. The same concept has been used by the US Food and Drug Administration (FDA) to establish "thresholds of regulation" for indirect food additives and adopted by the Joint FAO/WHO Expert Committee on Food Additives for flavoring substances. In practice, these values are used as a statement of safety and indicate when no actions need to be taken in a given exposure situation. Pharmaceutical manufacturing relies on ADIs for cleaning validation of process equipment and atypical extraneous matter investigations. To provide practical guidance for handling situations where relatively unstudied compounds with limited or no toxicity data are encountered, recommendations are provided on ADI values that correspond to three categories of compounds: (1) compounds that are likely to be carcinogenic, (2) compounds that are likely to be potent or highly toxic, and (3) compounds that are not likely to be potent, highly toxic or carcinogenic. Corresponding ADIs for these categories of materials are 1, 10, and 100 microg/day, respectively.

  9. Tokamaks with high-performance resistive magnets: advanced test reactors and prospects for commercial applications

    International Nuclear Information System (INIS)

    Bromberg, L.; Cohn, D.R.; Williams, J.E.C.; Becker, H.; Leclaire, R.; Yang, T.

    1981-10-01

    Scoping studies have been made of tokamak reactors with high performance resistive magnets which maximize advantages gained from high field operation and reduced shielding requirements, and minimize resistive power requirements. High field operation can provide very high values of fusion power density and n tau/sub e/ while the resistive power losses can be kept relatively small. Relatively high values of Q' = Fusion Power/Magnet Resistive Power can be obtained. The use of high field also facilitates operation in the DD-DT advanced fuel mode. The general engineering and operational features of machines with high performance magnets are discussed. Illustrative parameters are given for advanced test reactors and for possible commercial reactors. Commercial applications that are discussed are the production of fissile fuel, electricity generation with and without fissioning blankets and synthetic fuel production

  10. A spreadsheet-based microcomputer application for determining cost-effectiveness of commercial lighting retrofit opportunities

    International Nuclear Information System (INIS)

    Spain, T.K.

    1992-01-01

    Lighting accounts for 20-25% of electricity use in the United States. With estimates of 50-70% potential reductions being made by energy engineers, lighting is a promising area for cost-effective energy conservation projects in commercial buildings. With an extensive array of alternatives available to replace or modify existing lighting systems, simple but effective calculation tools are needed to help energy auditors evaluate lighting retrofits. This paper describes a spreadsheet-based microcomputer application for determining the cost-effectiveness of commercial lighting retrofits. Developed to support walk-through energy audits conducted by the Industrial Energy Advisory Service (IdEAS), the spreadsheet provides essential comparative data for evaluating the payback of alternatives. The impact of alternatives on environmental emissions is calculated to help communicate external costs and sell the project, if appropriate. The methodology and calculations are fully documented to allow the user to duplicate the spreadsheet and modify it as needed

  11. Methodology for validating technical tools to assess customer Demand Response: Application to a commercial customer

    International Nuclear Information System (INIS)

    Alcazar-Ortega, Manuel; Escriva-Escriva, Guillermo; Segura-Heras, Isidoro

    2011-01-01

    The authors present a methodology, which is demonstrated with some applications to the commercial sector, in order to validate a Demand Response (DR) evaluation method previously developed and applied to a wide range of industrial and commercial segments, whose flexibility was evaluated by modeling. DR is playing a more and more important role in the framework of electricity systems management for the effective integration of other distributed energy resources. Consequently, customers must identify what they are using the energy for in order to use their flexible loads for management purposes. Modeling tools are used to predict the impact of flexibility on the behavior of customers, but this result needs to be validated since both customers and grid operators have to be confident in these flexibility predictions. An easy-to-use two-steps method to achieve this goal is presented in this paper.

  12. Mapping the value of commercial PV applications in the US -- Accounting for externalities

    International Nuclear Information System (INIS)

    Perez, R.; Kmiecik, M.; Herig, C.; Wenger, H.

    1999-01-01

    In previous publications, the authors reported on the geographical distribution of the economic feasibility of customer-owned commercial PV systems in the US. The results showed that several regions in the country were near or above economic breakeven. However, the authors noted that these results only reflected business as usual assumptions. They did not account for existing or prospective external value elements that could, depending on the application, considerably increase PV's feasibility threshold. In this paper, the authors look at the individual and combined impact of the following value elements: (1) Replacement Value, (2) enhanced load management value, (3) emergency value and (4) environmental value. They show that accounting for these elements could significantly increase the size of cost-effective niche markets for customer-owned commercial PV installation

  13. Residential-commercial energy input estimation based on genetic algorithm (GA) approaches: an application of Turkey

    International Nuclear Information System (INIS)

    Ozturk, H.K.; Canyurt, O.E.; Hepbasli, A.; Utlu, Z.

    2004-01-01

    The main objective of the present study is to develop the energy input estimation equations for the residential-commercial sector (RCS) in order to estimate the future projections based on genetic algorithm (GA) notion and to examine the effect of the design parameters on the energy input of the sector. For this purpose, the Turkish RCS is given as an example. The GA Energy Input Estimation Model (GAEIEM) is used to estimate Turkey's future residential-commercial energy input demand based on gross domestic product (GDP), population, import, export, house production, cement production and basic house appliances consumption figures. It may be concluded that the three various forms of models proposed here can be used as an alternative solution and estimation techniques to available estimation techniques. It is also expected that this study will be helpful in developing highly applicable and productive planning for energy policies. (author)

  14. Effects of retail style or food service style packaging type and storage time on sensory characteristics of bacon manufactured from commercially sourced pork bellies.

    Science.gov (United States)

    Lowe, B K; Bohrer, B M; Holmer, S F; Boler, D D; Dilger, A C

    2014-06-01

    Objectives were to characterize differences in pork bellies that were stored frozen for different durations prior to processing and characterize sensory properties of the bacon derived from those bellies when stored in either retail or food service style packaging. Bellies (n = 102) were collected from 4 different time periods, fresh bellies (never frozen) and bellies frozen for 2, 5, or 7 mo, and manufactured into bacon under commercial conditions. Food service bacon was packaged in oxygen-permeable polyvinyl lined boxes layered on wax-covered lined paper and blast frozen (-33 °C) for 45 or 90 d after slicing. Retail bacon was vacuum-packaged in retail packages and refrigerated (2 °C) in the dark for 60 or 120 d after slicing. At the end of respective storage times after slicing, bacon was analyzed for sensory attributes and lipid oxidation. Off-flavor and oxidized odor of bacon increased (P food service packaged bacon from frozen bellies, but was unchanged (P ≥ 0.07) with time in food service packaged bacon from fresh bellies. Lipid oxidation was also unchanged (P ≥ 0.21) over time in retail packaged bacon, with the exception of bellies frozen for 5 mo, which was increased from day 0 to day 90. Overall, off-flavor, oxidized odor, and lipid oxidation increased as storage time after processing increased. Freezing bellies before processing may exacerbate lipid oxidation as storage time after processing was extended. Bacon can be packaged and managed several different ways before it reaches the consumer. This research simulated food service (frozen) and retail packaged (refrigerated) bacon over a range of storage times after slicing. Off-flavor and oxidized odor increased as storage time after processing increased in both packaging types. Lipid oxidation increased as storage time after slicing increased to a greater extent in food service packaging. © 2014 Institute of Food Technologists®

  15. Application of contemporary integrated manufacture systems to nuclear power plants management

    International Nuclear Information System (INIS)

    Zhou Gang; Wang Lushuai; Tang Yaoyang

    2005-01-01

    In order to improve the safety, economy and reliability of the operation of a nuclear power plant (NPP), a novel integrated management method is proposed based on the 'integration' concept of the computer and contemporary integrated manufacture systems (CIMS). The design of integrated management system for NPP is studied. In the design of this system, information integration method based on the database and product data management (PDM) technology is adopted. In order to design and integrated management system satisfying the needs of NPP management, all activities of NPP are divided into different categories according to its characteristics. There are subsystems under the general management system to conduct the management work of different categories. All subsystems are interrelated in the environment of CIMS, but relatively independent. The application of CIMS to NPP provides a new way for scientific management of NPP, and makes the best of human, material and information resources. (authors)

  16. Additive Biotech-Chances, challenges, and recent applications of additive manufacturing technologies in biotechnology.

    Science.gov (United States)

    Krujatz, Felix; Lode, Anja; Seidel, Julia; Bley, Thomas; Gelinsky, Michael; Steingroewer, Juliane

    2017-10-25

    The diversity and complexity of biotechnological applications are constantly increasing, with ever expanding ranges of production hosts, cultivation conditions and measurement tasks. Consequently, many analytical and cultivation systems for biotechnology and bioprocess engineering, such as microfluidic devices or bioreactors, are tailor-made to precisely satisfy the requirements of specific measurements or cultivation tasks. Additive manufacturing (AM) technologies offer the possibility of fabricating tailor-made 3D laboratory equipment directly from CAD designs with previously inaccessible levels of freedom in terms of structural complexity. This review discusses the historical background of these technologies, their most promising current implementations and the associated workflows, fabrication processes and material specifications, together with some of the major challenges associated with using AM in biotechnology/bioprocess engineering. To illustrate the great potential of AM, selected examples in microfluidic devices, 3D-bioprinting/biofabrication and bioprocess engineering are highlighted. Copyright © 2017 Elsevier B.V. All rights reserved.

  17. Application of artificial intelligence (AI) methods for designing and analysis of reconfigurable cellular manufacturing system (RCMS)

    CSIR Research Space (South Africa)

    Xing, B

    2009-12-01

    Full Text Available This work focuses on the design and control of a novel hybrid manufacturing system: Reconfigurable Cellular Manufacturing System (RCMS) by using Artificial Intelligence (AI) approach. It is hybrid as it combines the advantages of Cellular...

  18. Study of mandible reconstruction using a fibula flap with application of additive manufacturing technology.

    Science.gov (United States)

    Tsai, Ming-June; Wu, Ching-Tsai

    2014-05-06

    This study aimed to establish surgical guiding techniques for completing mandible lesion resection and reconstruction of the mandible defect area with fibula sections in one surgery by applying additive manufacturing technology, which can reduce the surgical duration and enhance the surgical accuracy and success rate. A computer assisted mandible reconstruction planning (CAMRP) program was used to calculate the optimal cutting length and number of fibula pieces and design the fixtures for mandible cutting, registration, and arrangement of the fibula segments. The mandible cutting and registering fixtures were then generated using an additive manufacturing system. The CAMRP calculated the optimal fibula cutting length and number of segments based on the location and length of the defective portion of the mandible. The mandible cutting jig was generated according to the boundary surface of the lesion resection on the mandible STL model. The fibular cutting fixture was based on the length of each segment, and the registered fixture was used to quickly arrange the fibula pieces into the shape of the defect area. In this study, the mandibular lesion was reconstructed using registered fibular sections in one step, and the method is very easy to perform. The application of additive manufacturing technology provided customized models and the cutting fixtures and registered fixtures, which can improve the efficiency of clinical application. This study showed that the cutting fixture helped to rapidly complete lesion resection and fibula cutting, and the registered fixture enabled arrangement of the fibula pieces and allowed completion of the mandible reconstruction in a timely manner. Our method can overcome the disadvantages of traditional surgery, which requires a long and different course of treatment and is liable to cause error. With the help of optimal cutting planning by the CAMRP and the 3D printed mandible resection jig and fibula cutting fixture, this all

  19. ANALYSIS AND APPLICATION PROSPECTS OF EFFECTIVE RESOURCES-SAVING TECHNOLOGIES IN CONCRETE MANUFACTURE

    Directory of Open Access Journals (Sweden)

    H. P. Ivanova

    2014-10-01

    Full Text Available Purpose. Prospectivity assessments of the nano-materials usage in construction technologies at the same time meeting the requirements of environmental safety and rational use of the natural resources. Methodology. During the study the building composites, in particular concretes, which are obtained on the base of the raw materials, which are introduced in the array of micro- and nanolevels were researched and analyzed. The deformation and deterioration processes of nanostructured concrete depending on their composition and manufacture parameters were simulated. Findings. Concrete manufacture is in the direct dependence on its components. Due to the extraction and processing of these components land degradation occurs because of soil destruction with oversize pits, which threatens the ecology of the environment. In this connection there is a need for another concept of building materials receiving for concrete manufacture. The new branch of science based on nanotechnologies, nanomaterials and nanostructuring is a key to its foundation. The special features of nanostructured concretes are the nanoagents in their composition (carbon nanotubes, mechanoactivated slags of blast furnace production. The study of deformation patterns and concrete deterioration based on the mechanoactivated material will purposefully affect the structure, physical and chemical properties, as well as the mechanical and deformational ones. Originality. The researches have shown that nano-structured concrete had high fluidity. The strength of such compositions is enhanced up to 13 % without reduction of concrete consumption and up to 8.8% at 10% reduced concrete consumption. Practical value. The application of the structured concretes based on the mechanoactivated material will increase the efficiency of the industrial wastes recycling and improve the physical, mechanical and technological properties of the produced composites. From the standpoint of the economic benefits

  20. Manufacturability evaluation for molded parts using fictitious physical models, and its application in topology optimization

    OpenAIRE

    Sato, Yuki; Yamada, Takayuki; Izui, Kazuhiro; Nishiwaki, Shinji

    2017-01-01

    Manufacturing methods using molds, such as casting and injection molding, are widely used in industries. A basic requirement when using such manufacturing methods is that design engineers must design products so that they incorporate certain geometrical features that allow the mold parts to be removed from the created solid object. In the present study, we propose a manufacturability evaluation method especially adapted for the use of molds. To evaluate the manufacturability, we introduce fic...

  1. Applications of picosecond lasers and pulse-bursts in precision manufacturing

    Science.gov (United States)

    Knappe, Ralf

    2012-03-01

    Just as CW and quasi-CW lasers have revolutionized the materials processing world, picosecond lasers are poised to change the world of micromachining, where lasers outperform mechanical tools due to their flexibility, reliability, reproducibility, ease of programming, and lack of mechanical force or contamination to the part. Picosecond lasers are established as powerful tools for micromachining. Industrial processes like micro drilling, surface structuring and thin film ablation benefit from a process, which provides highest precision and minimal thermal impact for all materials. Applications such as microelectronics, semiconductor, and photovoltaic industries use picosecond lasers for maximum quality, flexibility, and cost efficiency. The range of parts, manufactured with ps lasers spans from microscopic diamond tools over large printing cylinders with square feet of structured surface. Cutting glass for display and PV is a large application, as well. With a smart distribution of energy into groups of ps-pulses at ns-scale separation (known as burst mode) ablation rates can be increased by one order of magnitude or more for some materials, also providing a better surface quality under certain conditions. The paper reports on the latest results of the laser technology, scaling of ablation rates, and various applications in ps-laser micromachining.

  2. Assessment of the Current Level of Automation in the Manufacture of Fuel Cell Systems for Combined Heat and Power Applications

    Energy Technology Data Exchange (ETDEWEB)

    Ulsh, M.; Wheeler, D.; Protopappas, P.

    2011-08-01

    The U.S. Department of Energy (DOE) is interested in supporting manufacturing research and development (R&D) for fuel cell systems in the 10-1,000 kilowatt (kW) power range relevant to stationary and distributed combined heat and power applications, with the intent to reduce manufacturing costs and increase production throughput. To assist in future decision-making, DOE requested that the National Renewable Energy Laboratory (NREL) provide a baseline understanding of the current levels of adoption of automation in manufacturing processes and flow, as well as of continuous processes. NREL identified and visited or interviewed key manufacturers, universities, and laboratories relevant to the study using a standard questionnaire. The questionnaire covered the current level of vertical integration, the importance of quality control developments for automation, the current level of automation and source of automation design, critical balance of plant issues, potential for continuous cell manufacturing, key manufacturing steps or processes that would benefit from DOE support for manufacturing R&D, the potential for cell or stack design changes to support automation, and the relationship between production volume and decisions on automation.

  3. The Application of Lean Manufacturing for Operation Improvement: A Case Study of Black Cough Medicine Production in Indonesia

    Directory of Open Access Journals (Sweden)

    Pramadona Pramadona

    2013-09-01

    Full Text Available Nowadays, the pharmaceutical industry has a market tends to be unstable and volatile in meeting customer needs. This is due to the economic crisis that occurred in different parts of the world. The pharmaceutical industry currently uses good manufacturing practices (cGMP to ensure that products are consistently produced and controlled according to the required standards. Pharmaceutical industry slowly started to move from cGMP to lean manufacturing that focused on reducing operating costs while ensuring compliance. The purpose of this paper is to analyze the usage of lean manufacturing instead of the usage of cGMP to eliminate wastes. To conduct this study, literature review and company visit has been done. This analysis was applied by using value stream mapping (VSM and 7-wastes methodology to analyze the problems in the OBH (Black Cough Medicine production line one of the pharmaceutical industry in Bandung, Indonesia. For the improvement, the lean manufacturing approach has been carried out and the future VSM has been developed. Finding reveals that the application of lean manufacturing in the cGMP environment helps the company to eliminate wastes in reducing lead time and cycle time in the manufacturing process. Keywords: pharmaceutical industry, cGMP, lean manufacturing, value stream mapping, 7-wastes.

  4. Commercial applications of large-scale Research and Development computer simulation technologies

    International Nuclear Information System (INIS)

    Kuok Mee Ling; Pascal Chen; Wen Ho Lee

    1998-01-01

    The potential commercial applications of two large-scale R and D computer simulation technologies are presented. One such technology is based on the numerical solution of the hydrodynamics equations, and is embodied in the two-dimensional Eulerian code EULE2D, which solves the hydrodynamic equations with various models for the equation of state (EOS), constitutive relations and fracture mechanics. EULE2D is an R and D code originally developed to design and analyze conventional munitions for anti-armor penetrations such as shaped charges, explosive formed projectiles, and kinetic energy rods. Simulated results agree very well with actual experiments. A commercial application presented here is the design and simulation of shaped charges for oil and gas well bore perforation. The other R and D simulation technology is based on the numerical solution of Maxwell's partial differential equations of electromagnetics in space and time, and is implemented in the three-dimensional code FDTD-SPICE, which solves Maxwell's equations in the time domain with finite-differences in the three spatial dimensions and calls SPICE for information when nonlinear active devices are involved. The FDTD method has been used in the radar cross-section modeling of military aircrafts and many other electromagnetic phenomena. The coupling of FDTD method with SPICE, a popular circuit and device simulation program, provides a powerful tool for the simulation and design of microwave and millimeter-wave circuits containing nonlinear active semiconductor devices. A commercial application of FDTD-SPICE presented here is the simulation of a two-element active antenna system. The simulation results and the experimental measurements are in excellent agreement. (Author)

  5. Prepreg effects on honeycomb composite manufacturing

    Science.gov (United States)

    Martin, Cary Joseph

    Fiber reinforced composites offer many advantages over traditional materials and are widely utilized in aerospace applications. Advantages include a high stiffness to weight ratio and excellent fatigue resistance. However, the pace of new implementation is slow. The manufacturing processes used to transform composite intermediates into final products are poorly understood and are a source of much variability. This limits new implementation and increases the manufacturing costs of existing designs. One such problem is honeycomb core crush, in which a core-stiffened structure collapses during autoclave manufacture, making the structure unusable and increasing the overall manufacturing cost through increased scrap rates. Consequently, the major goal of this research was to investigate the scaling of core crush from prepreg process-structure-property relations to commercial composite manufacture. The material dependent nature of this defect was of particular interest. A methodology and apparatus were developed to measure the frictional resistance of prepreg materials under typical processing conditions. Through a characterization of commercial and experimental prepregs, it was found that core crush behavior was the result of differences in prepreg frictional resistance. This frictional resistance was related to prepreg morphology and matrix rheology and elasticity. Resin composition and prepreg manufacturing conditions were also found to affect manufacturing behavior. Mechanical and dimensional models were developed and demonstrated utility for predicting this crushing behavior. Collectively, this work explored and identified the process-structure-property relations as they relate to the manufacture of composite materials and suggested several avenues by which manufacturing-robust materials may be developed.

  6. Integrated vehicle control and guidance systems in unmanned ground vehicles for commercial applications

    Science.gov (United States)

    Kenyon, Chase H.

    1995-01-01

    While there is a lot of recent development in the entire IVHS field, very few have had the opportunity to combine the many areas of development into a single integrated `intelligent' unmanned vehicle. One of our systems was developed specifically to serve a major automobile manufacturer's need for an automated vehicle chassis durability test facility. Due to the severity of the road surface human drivers could not be used. A totally automated robotic vehicle driver and guidance system was necessary. In order to deliver fixed price commercial projects now, it was apparent system and component costs were of paramount importance. Cyplex has developed a robust, cost effective single wire guidance system. This system has inherent advantages in system simplicity. Multi-signal (per vehicle lane) systems complicate path planning and layout when multiple lanes and lane changes are required, as on actual highways. The system has demonstrated high enough immunity to rain and light snow cover that normal safety reductions in speed are adequate to stay within the required system performance envelope. This system and it's antenna interface have shown the ability to guide the vehicle at slow speeds (10 MPH) with a tracking repeatability of plus or minus 1/8 of an inch. The basic guide and antenna system has been tested at speeds up to 80 mph. The system has inherently superior abilities for lane changes and precision vehicle placement. The operation of this system will be described and the impact of a system that is commercially viable now for highway and off road use will be discussed.

  7. Intersatellite Link (ISL) application to commercial communications satellites. Volume 1: Executive summary

    Science.gov (United States)

    Young, S. Lee

    1987-01-01

    Based on a comprehensive evaluation of the fundamental Intersatellite Link (ISL) systems characteristics, potential applications of ISLs to domestic, regional, and global commercial satellite communications were identified, and their cost-effectiveness and other systems benefits quantified wherever possible. Implementation scenarios for the cost-effective communications satellite systems employing ISLs were developed for the first launch in 1993 to 1994 and widespread use of ISLs in the early 2000's. Critical technology requirements for both the microwave (60 GHz) and optical (0.85 micron) ISL implementations were identified, and their technology development programs, including schedule and cost estimates, were derived.

  8. Note: Commercial SQUID magnetometer-compatible NMR probe and its application for studying a quantum magnet.

    Science.gov (United States)

    Vennemann, T; Jeong, M; Yoon, D; Magrez, A; Berger, H; Yang, L; Živković, I; Babkevich, P; Rønnow, H M

    2018-04-01

    We present a compact nuclear magnetic resonance (NMR) probe which is compatible with a magnet of a commercial superconducting quantum interference device magnetometer and demonstrate its application to the study of a quantum magnet. We employ trimmer chip capacitors to construct an NMR tank circuit for low temperature measurements. Using a magnetic insulator MoOPO 4 with S = 1/2 (Mo 5+ ) as an example, we show that the T-dependence of the circuit is weak enough to allow the ligand-ion NMR study of magnetic systems. Our 31 P NMR results are compatible with previous bulk susceptibility and neutron scattering experiments and furthermore reveal unconventional spin dynamics.

  9. An application of commercial data averaging techniques in pulsed photothermal experiments

    International Nuclear Information System (INIS)

    Grozescu, I.V.; Moksin, M.M.; Wahab, Z.A.; Yunus, W.M.M.

    1997-01-01

    We present an application of data averaging technique commonly implemented in many commercial digital oscilloscopes or waveform digitizers. The technique was used for transient data averaging in the pulsed photothermal radiometry experiments. Photothermal signals are surrounded by an important amount of noise which affect the precision of the measurements. The effect of the noise level on photothermal signal parameters in our particular case, fitted decay time, is shown. The results of the analysis can be used in choosing the most effective averaging technique and estimating the averaging parameter values. This would help to reduce the data acquisition time while improving the signal-to-noise ratio

  10. A proposed acceptance process for commercial off-the-shelf (COTS) software in reactor applications

    International Nuclear Information System (INIS)

    Preckshot, G.G.; Scott, J.A.

    1996-03-01

    This paper proposes a process for acceptance of commercial off-the-shelf (COTS) software products for use in reactor systems important to safety. An initial set of four criteria establishes COTS software product identification and its safety category. Based on safety category, three sets of additional criteria, graded in rigor, are applied to approve/disapprove the product. These criteria fall roughly into three areas: product assurance, verification of safety function and safety impact, and examination of usage experience of the COTS product in circumstances similar to the proposed application. A report addressing the testing of existing software is included as an appendix

  11. Evaluations of the commercial spectrometer systems for safeguards applications using the germanium detectors

    International Nuclear Information System (INIS)

    Vo, D.T.

    1998-01-01

    Safeguards applications require the best spectrometer systems with excellent resolution, stability, and throughput. Instruments must perform well in all the situations and environments. Data communication to the computer should be convenient, fast, and reliable. The software should have all the necessary tools and be ease to use. Portable systems should be small in size, lightweight, and have a long battery life. Nine commercially available spectrometer systems are tested with both the planar and coaxial germanium detectors. Considering the performance of the Digital Signal Processors (DSP), digital-based spectroscopy may be the future of gamma-ray spectroscopy

  12. Note: Commercial SQUID magnetometer-compatible NMR probe and its application for studying a quantum magnet

    Science.gov (United States)

    Vennemann, T.; Jeong, M.; Yoon, D.; Magrez, A.; Berger, H.; Yang, L.; Živković, I.; Babkevich, P.; Rønnow, H. M.

    2018-04-01

    We present a compact nuclear magnetic resonance (NMR) probe which is compatible with a magnet of a commercial superconducting quantum interference device magnetometer and demonstrate its application to the study of a quantum magnet. We employ trimmer chip capacitors to construct an NMR tank circuit for low temperature measurements. Using a magnetic insulator MoOPO4 with S = 1/2 (Mo5+) as an example, we show that the T-dependence of the circuit is weak enough to allow the ligand-ion NMR study of magnetic systems. Our 31P NMR results are compatible with previous bulk susceptibility and neutron scattering experiments and furthermore reveal unconventional spin dynamics.

  13. Additive manufacturing of metals

    International Nuclear Information System (INIS)

    Herzog, Dirk; Seyda, Vanessa; Wycisk, Eric; Emmelmann, Claus

    2016-01-01

    Additive Manufacturing (AM), the layer-by layer build-up of parts, has lately become an option for serial production. Today, several metallic materials including the important engineering materials steel, aluminium and titanium may be processed to full dense parts with outstanding properties. In this context, the present overview article describes the complex relationship between AM processes, microstructure and resulting properties for metals. It explains the fundamentals of Laser Beam Melting, Electron Beam Melting and Laser Metal Deposition, and introduces the commercially available materials for the different processes. Thereafter, typical microstructures for additively manufactured steel, aluminium and titanium are presented. Special attention is paid to AM specific grain structures, resulting from the complex thermal cycle and high cooling rates. The properties evolving as a consequence of the microstructure are elaborated under static and dynamic loading. According to these properties, typical applications are presented for the materials and methods for conclusion.

  14. The Application of Time-Delay Dependent H∞ Control Model in Manufacturing Decision Optimization

    Directory of Open Access Journals (Sweden)

    Haifeng Guo

    2015-01-01

    Full Text Available This paper uses a time-delay dependent H∞ control model to analyze the effect of manufacturing decisions on the process of transmission from resources to capability. We establish a theoretical framework of manufacturing management process based on three terms: resource, manufacturing decision, and capability. Then we build a time-delay H∞ robust control model to analyze the robustness of manufacturing management. With the state feedback controller between manufacturing resources and decision, we find that there is an optimal decision to adjust the process of transmission from resources to capability under uncertain environment. Finally, we provide an example to prove the robustness of this model.

  15. Electric poling-assisted additive manufacturing process for PVDF polymer-based piezoelectric device applications

    International Nuclear Information System (INIS)

    Lee, ChaBum; Tarbutton, Joshua A

    2014-01-01

    This paper presents a new additive manufacturing (AM) process to directly and continuously print piezoelectric devices from polyvinylidene fluoride (PVDF) polymeric filament rods under a strong electric field. This process, called ‘electric poling-assisted additive manufacturing or EPAM, combines AM and electric poling processes and is able to fabricate free-form shape piezoelectric devices continuously. In this process, the PVDF polymer dipoles remain well-aligned and uniform over a large area in a single design, production and fabrication step. During EPAM process, molten PVDF polymer is simultaneously mechanically stresses in-situ by the leading nozzle and electrically poled by applying high electric field under high temperature. The EPAM system was constructed to directly print piezoelectric structures from PVDF polymeric filament while applying high electric field between nozzle tip and printing bed in AM machine. Piezoelectric devices were successfully fabricated using the EPAM process. The crystalline phase transitions that occurred from the process were identified by using the Fourier transform infrared spectroscope. The results indicate that devices printed under a strong electric field become piezoelectric during the EPAM process and that stronger electric fields result in greater piezoelectricity as marked by the electrical response and the formation of sharper peaks at the polar β crystalline wavenumber of the PVDF polymer. Performing this process in the absence of an electric field does not result in dipole alignment of PVDF polymer. The EPAM process is expected to lead to the widespread use of AM to fabricate a variety of piezoelectric PVDF polymer-based devices for sensing, actuation and energy harvesting applications with simple, low cost, single processing and fabrication step. (paper)

  16. SP-100 nuclear space power systems with application to space commercialization

    International Nuclear Information System (INIS)

    Smith, J.M.

    1988-01-01

    The purpose of this paper is to familiarize the Space Commercialization Community with the status and characteristics of the SP-100 space nuclear power system. The program is a joint undertaking by the Department of Defense, the Department of Energy and NASA. The goal of the program is to develop, validate, and demonstrate the technology for space nuclear power systems in the range of 10 to 1000 kWe electric for use in the future civilian and military space missions. Also discussed are mission applications which are enhanced and/or enabled by SP-100 technology and how this technology compares to that of more familiar solar power systems. The mission applications include earth orbiting platforms and lunar/Mars surface power

  17. NRC research on the application of advanced I and C technology to commercial nuclear power plants

    International Nuclear Information System (INIS)

    Gollei, K.R.; Hon, A.L.

    1983-01-01

    The operational safety and efficiency of commercial nuclear power plants (NPP's) could possibly be enhanced by utilizing advanced instrumentation and control technology developed by other industries. The NRC is interested in learning about new I and C technology that probably will or could be applied to new or existing plants. This would enable the NRC to be better prepared to evaluate the application without undue delays. It would also help identify any appropriate changes in NRC regulations or guidance necessary to facilitate the application of advanced IandC technology to NPP's. The NRC has initiated a project to work cooperatively with the advanced technology industry, power industry, EPRI, and technical organizations such as ISA toward this goal. This paper describes the objectives and plans of this cooperative effort. It summarizes the highlights of some of the advanced technology already being evaluated by NRC such as microprocessor applications, instruments to detect inadequate core cooling and other two-phase flow measurements, reactor noise surveillance and diagnostic techniques. This paper also suggests potential candidates for consideration such as utilization of advanced instruments for LOCA experiments. It also identifies some of the potential challenges facing the application of advanced technology to NPP's. It concludes that close cooperation between NRC and industry is essential for the success of such applications

  18. Commercial Smartphone-Based Devices and Smart Applications for Personalized Healthcare Monitoring and Management.

    Science.gov (United States)

    Vashist, Sandeep Kumar; Schneider, E Marion; Luong, John H T

    2014-08-18

    Smartphone-based devices and applications (SBDAs) with cost effectiveness and remote sensing are the most promising and effective means of delivering mobile healthcare (mHealthcare). Several SBDAs have been commercialized for the personalized monitoring and/or management of basic physiological parameters, such as blood pressure, weight, body analysis, pulse rate, electrocardiograph, blood glucose, blood glucose saturation, sleeping and physical activity. With advances in Bluetooth technology, software, cloud computing and remote sensing, SBDAs provide real-time on-site analysis and telemedicine opportunities in remote areas. This scenario is of utmost importance for developing countries, where the number of smartphone users is about 70% of 6.8 billion cell phone subscribers worldwide with limited access to basic healthcare service. The technology platform facilitates patient-doctor communication and the patients to effectively manage and keep track of their medical conditions. Besides tremendous healthcare cost savings, SBDAs are very critical for the monitoring and effective management of emerging epidemics and food contamination outbreaks. The next decade will witness pioneering advances and increasing applications of SBDAs in this exponentially growing field of mHealthcare. This article provides a critical review of commercial SBDAs that are being widely used for personalized healthcare monitoring and management.

  19. Commercial Smartphone-Based Devices and Smart Applications for Personalized Healthcare Monitoring and Management

    Directory of Open Access Journals (Sweden)

    Sandeep Kumar Vashist

    2014-08-01

    Full Text Available Smartphone-based devices and applications (SBDAs with cost effectiveness and remote sensing are the most promising and effective means of delivering mobile healthcare (mHealthcare. Several SBDAs have been commercialized for the personalized monitoring and/or management of basic physiological parameters, such as blood pressure, weight, body analysis, pulse rate, electrocardiograph, blood glucose, blood glucose saturation, sleeping and physical activity. With advances in Bluetooth technology, software, cloud computing and remote sensing, SBDAs provide real-time on-site analysis and telemedicine opportunities in remote areas. This scenario is of utmost importance for developing countries, where the number of smartphone users is about 70% of 6.8 billion cell phone subscribers worldwide with limited access to basic healthcare service. The technology platform facilitates patient-doctor communication and the patients to effectively manage and keep track of their medical conditions. Besides tremendous healthcare cost savings, SBDAs are very critical for the monitoring and effective management of emerging epidemics and food contamination outbreaks. The next decade will witness pioneering advances and increasing applications of SBDAs in this exponentially growing field of mHealthcare. This article provides a critical review of commercial SBDAs that are being widely used for personalized healthcare monitoring and management.

  20. Micro Manufacturing

    DEFF Research Database (Denmark)

    Hansen, Hans Nørgaard

    2003-01-01

    Manufacturing deals with systems that include products, processes, materials and production systems. These systems have functional requirements, constraints, design parameters and process variables. They must be decomposed in a systematic manner to achieve the best possible system performance....... If a micro manufacturing system isn’t designed rationally and correctly, it will be high-cost, unreliable, and not robust. For micro products and systems it is a continuously increasing challenge to create the operational basis for an industrial production. As the products through product development...... processes are made applicable to a large number of customers, the pressure in regard to developing production technologies that make it possible to produce the products at a reasonable price and in large numbers is growing. The micro/nano manufacturing programme at the Department of Manufacturing...

  1. Study on the Transformation and Upgrade of E-Commerce Application in Manufacturing Industry

    OpenAIRE

    Zhao Liang; Feng Mengzhao

    2017-01-01

    Under the Internet thinking, manufacturing management mode is changed, it is not depend on the scale, but in the user as the center, more dependent on the reaction rate of user requirements. As the big data, cloud computing, Internet of things technology such as the development of technology, manufacturing is from automatic to intelligent evolution, on the user's personalized customization is possible. Using Internet thinking positive development manufacturing enterprise electronic commerce a...

  2. "Industrie 4.0" and Smart Manufacturing – A Review of Research Issues and Application Examples

    OpenAIRE

    Klaus-Dieter Thoben; Stefan Wiesner; Thorsten Wuest

    2017-01-01

    A fourth industrial revolution is occurring in global manufacturing. It is based on the introduction of Internet of things and servitization concepts into manufacturing companies, leading to vertically and horizontally integrated production systems. The resulting smart factories are able to fulfill dynamic customer demands with high variability in small lot sizes while integrating human ingenuity and automation. To support the manufacturing industry in this conversion process and enhance glob...

  3. Commercial Optimization of a 100 kg/day PEM based Hydrogen Generator For Energy and Industrial Applications

    International Nuclear Information System (INIS)

    Moulthrop, L.; Anderson, E.; Chow, O.; Friedland, R.; Maloney, T.; Schiller, M.

    2006-01-01

    Commercial hydrogen generators using PEM water electrolysis are well proven, serving industrial applications worldwide in over 50 countries. Now, market and environmental requirements are converging to demand larger on-site hydrogen generators. North American liquid H 2 shortages, increasing trucking costs, developing economies with no liquid infrastructure, utilities, and forklift fuel cell fueling applications are all working to increase market demand for commercial on-site H 2 generation. These commercial applications may be satisfied by a 100 kg H 2 /day module; this platform can be the pathway towards a 500 kg H 2 /day generator desired for small fore-court hydrogen vehicle fueling stations. This paper discusses the steps necessary and activities already underway to develop a 100 to 500 kg H 2 /day PEM hydrogen generator platform to meet commercial market cost targets and approach US DoE transportation fueling cost targets. (authors)

  4. Application of the flotation process in the silver recovery from the wastes generated during the silvery semi-products manufacturing

    OpenAIRE

    B. Oleksiak; A. Blacha-Grzechnik; G. Siwiec

    2012-01-01

    In this work, the results of the flotation process application in the silver recovery from the wastes generated during the silvery semi-products manufacturing, are shown. The flotation process parameters, i.e. time of process, rotation frequency, gas flow rate and flotation reagents, were optimized.

  5. Application of the flotation process in the silver recovery from the wastes generated during the silvery semi-products manufacturing

    Directory of Open Access Journals (Sweden)

    B. Oleksiak

    2012-07-01

    Full Text Available In this work, the results of the flotation process application in the silver recovery from the wastes generated during the silvery semi-products manufacturing, are shown. The flotation process parameters, i.e. time of process, rotation frequency, gas flow rate and flotation reagents, were optimized.

  6. 77 FR 47114 - Manufacturer of Controlled Substances; Notice of Application; AMRI Rensselaer, Inc.

    Science.gov (United States)

    2012-08-07

    ... Marihuana (7360) I Tetrahydrocannabinols (7370) I Amphetamine (1100) II Lisdexamfetamine (1205) II... (Marihuana), the company plans to bulk manufacture cannabidiol as a synthetic intermediate, which will be...

  7. Standardization of Good Manufacturing Practice-compliant production of bone marrow-derived human mesenchymal stromal cells for immunotherapeutic applications.

    Science.gov (United States)

    Wuchter, Patrick; Bieback, Karen; Schrezenmeier, Hubert; Bornhäuser, Martin; Müller, Lutz P; Bönig, Halvard; Wagner, Wolfgang; Meisel, Roland; Pavel, Petra; Tonn, Torsten; Lang, Peter; Müller, Ingo; Renner, Matthias; Malcherek, Georg; Saffrich, Rainer; Buss, Eike C; Horn, Patrick; Rojewski, Markus; Schmitt, Anita; Ho, Anthony D; Sanzenbacher, Ralf; Schmitt, Michael

    2015-02-01

    Human mesenchymal stem or stromal cells (MSCs) represent a potential resource not only for regenerative medicine but also for immunomodulatory cell therapies. The application of different MSC culture protocols has significantly hampered the comparability of experimental and clinical data from different laboratories and has posed a major obstacle for multicenter clinical trials. Manufacturing of cell products for clinical application in the European Community must be conducted in compliance with Good Manufacturing Practice and requires a manufacturing license. In Germany, the Paul-Ehrlich-Institut as the Federal Authority for Vaccines and Biomedicines is critically involved in the approval process. This report summarizes a consensus meeting between researchers, clinicians and regulatory experts on standard quality requirements for MSC production. The strategy for quality control testing depends on the product's cell composition, the manufacturing process and the indication and target patient population. Important quality criteria in this sense are, among others, the immunophenotype of the cells, composition of the culture medium and the risk for malignant transformation, as well as aging and the immunosuppressive potential of the manufactured MSCs. This position paper intends to provide relevant information to interested parties regarding these criteria to foster the development of scientifically valid and harmonized quality standards and to support approval of MSC-based investigational medicinal products. Copyright © 2015 International Society for Cellular Therapy. Published by Elsevier Inc. All rights reserved.

  8. Large-scale commercial applications of the in situ vitrification remediation technology

    International Nuclear Information System (INIS)

    Campbell, B.E.; Hansen, J.E.; McElroy, J.L.; Thompson, L.E.; Timmerman, C.L.

    1994-01-01

    The first large-scale commercial application of the innovative In Situ Vitrification (ISV) remediation technology was completed at the Parsons Chemical/ETM Enterprises Superfund site in Michigan State midyear 1994. This project involved treating 4,800 tons of pesticide and mercury-contaminated soil. The project also involved performance of the USEPA SITE Program demonstration test for the ISV technology. The Parsons project involved consolidation and staging of contaminated soil from widespread locations on and nearby the site. This paper presents a brief description of the ISV technology along with case-study type information on these two sites and the performance of the ISV technology on them. The paper also reviews other remediation projects where ISV has been identified as the/a preferred remedy, and where ISV is currently planned for use. These sites include soils contaminated with pesticides, dioxin, PCP, paint wastes, and a variety of heavy metals. This review of additional sites also includes a description of a planned radioactive mixed waste remediation project in Australia that contains large amounts of plutonium, uranium, lead, beryllium, and metallic and other debris buried in limestone and dolomitic soil burial pits. Initial test work has been completed on this application, and preparations are now underway for pilot testing in Australia. This project will demonstrate the applicability of the ISV technology to the challenging application of buried mixed wastes

  9. Range of Applicability and Bias Determination for Postclosure Criticality of Commercial Spent Nuclear Fuel

    International Nuclear Information System (INIS)

    Radulescu, Georgeta; Mueller, Don; Goluoglu, Sedat; Hollenbach, Daniel F; Fox, Patricia B

    2007-01-01

    The purpose of this calculation report, Range of Applicability and Bias Determination for Postclosure Criticality of Commercial Spent Nuclear Fuel, is to validate the computational method used to perform postclosure criticality calculations. The validation process applies the criticality analysis methodology approach documented in Section 3.5 of the Disposal Criticality Analysis Methodology Topical Report. The application systems for this validation consist of waste packages containing transport, aging, and disposal canisters (TAD) loaded with commercial spent nuclear fuel (CSNF) of varying assembly types, initial enrichments, and burnup values that are expected from the waste stream and of varying degree of internal component degradation that may occur over the 10,000-year regulatory time period. The criticality computational tool being evaluated is the general-purpose Monte Carlo N-Particle (MCNP) transport code. The nuclear cross-section data distributed with MCNP 5.1.40 and used to model the various physical processes are based primarily on the Evaluated Nuclear Data File/B Version VI (ENDF/B-VI) library. Criticality calculation bias and bias uncertainty and lower bound tolerance limit (LBTL) functions for CSNF waste packages are determined based on the guidance in ANSI/ANS 8.1-1998 (Ref. 4) and ANSI/ANS 8.17-2004 (Ref. 5), as described in Section 3.5.3 of Ref. 1. The development of this report is consistent with Test Plan for: Range of Applicability and Bias Determination for Postclosure Criticality. This calculation report has been developed in support of licensing activities for the proposed repository at Yucca Mountain, Nevada, and the results of the calculation may be used in the criticality evaluation for CSNF waste packages based on a conceptual TAD canister.

  10. Self-made silver-bromide-based emulsions for users in holography: manufacturing, processing, and application

    Science.gov (United States)

    Duenkel, Lothar; Eichler, Juergen; Ackermann, Gerhard; Schneeweiss, Claudia

    2004-06-01

    Holography is the most fascinating technology for three-dimensional imaging. But despite of many decades of research, the seek for an ideal recording material has never been given up. From all ultra-fine materials, silver bromide emulsions with very small grain sizes have the highest sensitivity. In recent years however, many traditional manufacturers discontinued their production. Meanwhile, newcomers succeeded in manufacturing emulsions which are very suitable for holography, concerning extremely high resolution, brigthness and sensitivity1. But two problems may still linger: First, the deficient market situation for production and application on this field. Second, the reputation of the system of being extremely complicated for laboratory preparation. In such a crucial situation, the authors have succeeded in presenting a laboratory procedure for making do-it-yourself materials available to any expert who is well versed in holography, and who disposes of normal darkroom equipment2. The methodology is based on precipitation using the traditional double-jet method according to Thiry and predecessors3. But sensitization is carried out by a diffusion process according to the procedure as proposed by Blyth et al.4 Thus, precipitation and coating on one side and sensitization on the other one are separated strictly from one another. Efficient desaltation is an important process too, warranting the high opto-mechanical quality of the layer. The material has been sensitzed for HeNe-Laser radiation (632,8 nm) only up to now. The mean diameter of the silver bromide grains is about 15 nm, as determined by transmission electron microscopy (TEM). Phillips-Bjelkhagen Ultimate (PBU) or Fe3+ rehalogenation bleach are applied successfully5-6. In final result, a new generation of holograms with ultra-high resolution, proper contrast, excellent sharpness and light brightness has been obtained. Holography belongs to an advancing technology where the search for an ideal recording

  11. Development of wall thinning screening system and its application to a commercial nuclear power plant

    International Nuclear Information System (INIS)

    Ryu, Kyung Ha; Hwang, Il Soon; Kim, Ji Hyun

    2013-01-01

    Highlights: • Wall loss screening system (WalSS) has been developed based on ES-DCPD method. • Screening criteria was established based on the thinning of the actual shape that occur in the power plant. • With the criteria, the WalSS gives priority of the need for inspection. • This technique was successfully applied to commercial nuclear power plant. - Abstract: A new non-destructive evaluation (NDE) method has been developed for metal pipes for the detection wall thinning. The method has been showed to be suitable for applications to electric power generation plants where flow accelerated corrosion (FAC) of carbon steel piping is a significant cause of increased maintenance and plant personnel casualty. The wall thinning screening system (WalSS) was developed in two major phases. In the first phase, the equipotential switching direct current potential drop (ES-DCPD) method was developed for piping wall (Ryu et al., 2008a, 2010). In the second phase, in this paper, a quantitative detection criteria was developed. The relative ES-DCPD change of 3.8% has been defined as the screening criteria for wall thinning schematization. This criteria means that the component with measured ES-DCPD change greater than 3.8% is called for a more comprehensive examination. In the criteria development, all variables were taken into consideration based on commercial plant piping inspection data such as initial thickness distributions, wall thinning shape and nominal thickness. The developed WalSS based on ES-DCPD was applied to a moisture separator reheater (MSR) drain line of a commercial nuclear power plant (NPP) during a scheduled overhaul. The measured ES-DCPD change was 2.16%, which is lower than the ES-DCPD criteria, identifying the pipe having adequate wall thickness. This is confirmed by site thickness inspection using ultrasonic technique (UT)

  12. Comparison of mechanical compressive properties of commercial and autologous fibrin glues for tissue engineering applications.

    Science.gov (United States)

    Cravens, Matthew G; Behn, Anthony W; Dragoo, Jason L

    2017-11-01

    Fibrin glues are widely used in orthopedic surgery as adhesives and hemostatic agents. We evaluated the compressive properties of selected fibrin glues in order to identify which are appropriate for tissue regeneration applications subject to compression. Uniaxial unconfined compression tests were performed on fibrin gels prepared from commercial and autologous products: (1) Evicel (Ethicon), (2) Tisseel (Baxter), (3) Angel (Arthrex), and (4) ProPlaz (Biorich). Cyclic loads were applied from 0 to 30% strain for 100cycles at 0.5Hz. Following cyclic testing, specimens were subjected to ramp displacement of 1% strain per second to 80% strain. Throughout cyclic loading, Evicel and Tisseel deformed (shortened) less than Angel at all but one time point, and deformed less than ProPlaz at cycles 10 and 20. The dynamic moduli, peak stress, and strain energy were significantly greater in Tisseel than all other groups. Evicel displayed significantly greater dynamic moduli, peak stress, and strain energy than Angel and ProPlaz. Following cyclic testing, Tisseel and Evicel were significantly less deformed than Angel. No specimens exhibited gross failure during ramp loading to 80% strain. Ramp loading trends mirrored those of cyclic loading. The tested commercial glues were significantly more resistant to compression than the autologous products. The compressive properties of Tisseel were approximately twice those of Evicel. All preparations displayed moduli multiple orders of magnitude less than that of native articular cartilage. We conclude that in knee surgeries requiring fibrin glue to undergo compression of daily activity, commercial products are preferable to autologous preparations from platelet-poor plasma, though both will deform significantly. Copyright © 2017 Elsevier Ltd. All rights reserved.

  13. Autoclaved lightweight aerated concrete. ; Manufacture/performance/application. Keiryo kiho concrete. ; Sono seiho kino yoto

    Energy Technology Data Exchange (ETDEWEB)

    Isome, Y. (Asahi Chemical Industry Co. Ltd., Tokyo (Japan))

    1993-10-20

    This paper reviews the manufacturing process, performance, and application of autoclaved lightweight aerated concrete (ALC). ALC is produced by a two-step process composed of molding and autoclaving, using quartz, lime, portland cement, and small quantities of aluminum as raw materials. In the molding step, aluminum reacts with alkali to generate hydrogen gas, thus forming air pores in the slurry. On the other hand, calcium silicate hydrates are produced by the reaction of lime and portland cement with water, resulting in formation of voids in the intergranular spaces vacated by the reacting water. In the autoclaving step, tobermorite (crystalline calcium silicate hydrates) is formed by the reaction of quartz and calcium silicate hydrates under high temperature and high pressure steam, and the intergranular voids are reduced to micropores in size as a result of the hydrothermal reaction. The air-pore and micropore structure adds unique physical properties to the ALC, such as fire resistance, heat insulation, lightness and strength. ALC is widely used as a useful material for homes and multistory buildings. 10 refs., 10 figs., 1 tab.

  14. Improvement of nuclear power plants within the perspective of applications of lean manufacturing practices

    Science.gov (United States)

    Malek, A. K.; Muhammad, H. I.; Rosmaini, A.; Alaa, A. S.; Falah, A. M.

    2017-09-01

    Development and improvement process are essential to the companies and factories of various kinds and this necessity is related aspects of cost, time and risk that can be avoided, these aspects are available at the nuclear power stations essential demands cannot be ignored. The lean management technique is one of the recent trends in the management system. Where the lean management is stated as the system increases the customer value and reduces the wastage process in an industry or in a power plants. Therefore, there is an urgent necessity to ensure the development and improvement in nuclear power plants in the pre-established in process of being established and stage of the management and production. All of these stages according to the study are closely related to the necessity operationalize and apply lean manufacturing practices that these applications are ineffective and clear contribution to reduce costs and control of production processes and the process of reducing future risks that could be exposed to the station.

  15. Extraction and Optimization of Potato Starch and Its Application as a Stabilizer in Yogurt Manufacturing

    Directory of Open Access Journals (Sweden)

    Ammar B. Altemimi

    2018-01-01

    Full Text Available Starch is increasingly used as a functional group in many industrial applications and foods due to its ability to work as a thickener. The experimental values of extracting starch from yellow skin potato indicate the processing conditions at 3000 rpm and 15 min as optimum for the highest yield of extracted starch. The effect of adding different concentrations of extracted starch under the optimized conditions was studied to determine the acidity, pH, syneresis, microbial counts, and sensory evaluation in stored yogurt manufactured at 5 °C for 15 days. The results showed that adding sufficient concentrations of starch (0.75%, 1% could provide better results in terms of the minimum change in the total acidity, decrease in pH, reduction in syneresis, and preferable results for all sensory parameters. The results revealed that the total bacteria count of all yogurt samples increased throughout the storage time. However, adding different concentrations of optimized extracted starch had a significant effect, decreasing the microbial content compared with the control sample (YC. In addition, the results indicated that coliform bacteria were not found during the storage time.

  16. An Easy to Manufacture Micro Gas Preconcentrator for Chemical Sensing Applications.

    Science.gov (United States)

    McCartney, Mitchell M; Zrodnikov, Yuriy; Fung, Alexander G; LeVasseur, Michael K; Pedersen, Josephine M; Zamuruyev, Konstantin O; Aksenov, Alexander A; Kenyon, Nicholas J; Davis, Cristina E

    2017-08-25

    We have developed a simple-to-manufacture microfabricated gas preconcentrator for MEMS-based chemical sensing applications. Cavities and microfluidic channels were created using a wet etch process with hydrofluoric acid, portions of which can be performed outside of a cleanroom, instead of the more common deep reactive ion etch process. The integrated heater and resistance temperature detectors (RTDs) were created with a photolithography-free technique enabled by laser etching. With only 28 V DC (0.1 A), a maximum heating rate of 17.6 °C/s was observed. Adsorption and desorption flow parameters were optimized to be 90 SCCM and 25 SCCM, respectively, for a multicomponent gas mixture. Under testing conditions using Tenax TA sorbent, the device was capable of measuring analytes down to 22 ppb with only a 2 min sample loading time using a gas chromatograph with a flame ionization detector. Two separate devices were compared by measuring the same chemical mixture; both devices yielded similar peak areas and widths (fwhm: 0.032-0.033 min), suggesting reproducibility between devices.

  17. Commercialization of an S-band standing-wave electron accelerator for industrial applications

    Science.gov (United States)

    Moon, Jin-Hyeok; Kwak, Gyeong-Il; Han, Jae-Ik; Lee, Gyu-Baek; Jeon, Seong-Hwan; Kim, Jae-Young; Hwang, Cheol-Bin; Lee, Gi-Yong; Kim, Young-Man; Park, Sung-Ju

    2016-09-01

    An electron accelerator system has been developed for use in industrial, as well as possible medical, applications. Based on our experiences achieved during prototype system development and various electron beam acceleration tests, we have built a stable and compact system for sales purposes. We have integrated a self-developed accelerating cavity, an E-gun pulse driver, a radio-frequency (RF) power system, a vacuum system, a cooling system, etc. into a frame with a size of 1800 × 1000 × 1500 mm3. The accelerating structure is a side-coupled standing-wave type operating in the π/2 mode (tuned to~3 GHz). The RF power is provided by using a magnetron driven by a solid-state modulator. The electron gun is a triode type with a dispenser cathode (diameter of 11 mm). The system is capable of delivering a maximum 900-W average electron beam power with tight focusing at the target. Until now, we have performed various electron beam tests and X-ray beam tests after having built the system, have completed the beam assessment for commercializations, and have been preparing full-fledged sales activity. This article reports on our system development processes and on some of our early test results for commercializations.

  18. Development of a Topical Resveratrol Formulation for Commercial Applications Using Dendrimer Nanotechnology.

    Science.gov (United States)

    Pentek, Tyler; Newenhouse, Eric; O'Brien, Brennin; Chauhan, Abhay Singh

    2017-01-14

    Resveratrol (RSV) is well known for its anti-oxidant and anti-aging properties. However, resveratrol is insoluble in water and has stability issues. Recently, efforts were placed to prepare a resveratrol-based advanced anti-aging topical product but it contains harsh organic solvents and oils that could be harmful to the human body and the environment. Hence, we propose the use of a multifunctional dendrimer to solve the solubility and stability issues of resveratrol. A dendrimer-resveratrol complex was prepared, optimized and tested for solubility enhancement, stability in solution and cream dosage forms. We have also developed a high performance liquid chromatography method to measure the resveratrol within the final product. PAMAM dendrimers increased the solubility and stability of resveratrol in water and semisolid dosage forms. Therefore, this product would be water based 'green' formulation devoid of harsh organic solvents and oils and can be safely applied to the skin. Additionally, we have shown that the dendrimer helped to increase overall RSV loading and skin penetration of resveratrol. The dendrimer-RSV formulation was successfully scaled up towards commercialization. Dendrimer with RSV has led to an innovation in anti-aging cream and solutions that could be commercially marketed. Dendrimer-RSV complex could also be added to other product forms for additional purposes and applications.

  19. Advances in commercial application of gamma radiation in tropical fruits at Brazil

    Science.gov (United States)

    Sabato, S. F.; Silva, J. M.; Cruz, J. N.; Broisler, P. O.; Rela, P. R.; Salmieri, S.; Lacroix, M.

    2009-07-01

    All regions of Brazil are potential areas for growing tropical fruits. As this country is already a great producer and exporter of tropical fruits, ionizing radiation has been the subject of studies in many commodities. An important project has been carried out to increase the commercial use of gamma radiation in our country. Instituto de Pesquisas Energeticas e Nucleares (IPEN)-CNEN/SP together with field producers in northeast region and partners like International Atomic Energy Agency (IAEA), CIC, Empresa Brasileira Pesquisa na Agricultura (EMBRAPA) joined to demonstrate this technology, its application and commercial feasibility. The objective of this study is to show advances in feasibility demonstrate the quality of the irradiated fruits in an international consignment from Brazil to Canada. In this work, Tommy Atkins mangoes harvested in northeast region of Brazil were sent to Canada. The fruits were treated in a gamma irradiation facility at doses 0.4 and 1.0 kGy. The control group was submitted to hydrothermal treatment (46 °C for 110 min). The fruits were stored at 11 °C for 10 days until the international transportation and kept at an environmental condition (22 °C) for 12 days, where their physical-chemical and sensorial properties were evaluated. The financial part of the feasibility study covers the scope of the investment, including the net working capital and production costs.

  20. Commercial and industrial applications of color ink jet: a technological perspective

    Science.gov (United States)

    Dunand, Alain

    1996-03-01

    In just 5 years, color ink-jet has become the dominant technology for printing color images and graphics in the office and home markets. In commercial printing, the traditional printing processes are being influenced by new digital techniques. Color ink-jet proofing, and concepts such as computer to film/plate or digital processes are contributing to the evolution of the industry. In industrial color printing, the penetration of digital techniques is just beginning. All widely used conventional contact printing technologies involve mechanical printing forms including plates, screens or engraved cylinders. Such forms, which need to be newly created and set up for each job, increase costs. In our era of fast changing customer demands, growing needs for customization, and increasing use of digital exchange of information, the commercial and industrial printing markets represent an enormous potential for digital printing technologies. The adoption characteristics for the use of color ink-jet in these industries are discussed. Examples of color ink-jet applications in the fields of billboard printing, floor/wall covering decoration, and textile printing are described. The requirements on print quality, productivity, reliability, substrate compatibility, and color lead to the consideration of various types of ink-jet technologies. Key technical enabling factors and directions for future improvements are presented.

  1. Advances in commercial application of gamma radiation in tropical fruits at Brazil

    International Nuclear Information System (INIS)

    Sabato, S.F.; Silva, J.M.; Cruz, J.N.; Broisler, P.O.; Rela, P.R.; Salmieri, S.; Lacroix, M.

    2009-01-01

    All regions of Brazil are potential areas for growing tropical fruits. As this country is already a great producer and exporter of tropical fruits, ionizing radiation has been the subject of studies in many commodities. An important project has been carried out to increase the commercial use of gamma radiation in our country. Instituto de Pesquisas Energeticas e Nucleares (IPEN)-CNEN/SP together with field producers in northeast region and partners like International Atomic Energy Agency (IAEA), CIC, Empresa Brasileira Pesquisa na Agricultura (EMBRAPA) joined to demonstrate this technology, its application and commercial feasibility. The objective of this study is to show advances in feasibility demonstrate the quality of the irradiated fruits in an international consignment from Brazil to Canada. In this work, Tommy Atkins mangoes harvested in northeast region of Brazil were sent to Canada. The fruits were treated in a gamma irradiation facility at doses 0.4 and 1.0 kGy. The control group was submitted to hydrothermal treatment (46 o C for 110 min). The fruits were stored at 11 o C for 10 days until the international transportation and kept at an environmental condition (22 o C) for 12 days, where their physical-chemical and sensorial properties were evaluated. The financial part of the feasibility study covers the scope of the investment, including the net working capital and production costs.

  2. Application of a B ampersand W developed computer aided pictorial process planning system to CQMS for manufacturing process control

    International Nuclear Information System (INIS)

    Johanson, D.C.; VandeBogart, J.E.

    1992-01-01

    Babcock ampersand Wilcox (B ampersand W) will utilize its internally developed Computer Aided Pictorial Process Planning or CAPPP (pronounced open-quotes cap cubedclose quotes) system to create a paperless manufacturing environment for the Collider Quadruple Magnets (CQM). The CAPPP system consists of networked personal computer hardware and software used to: (1) generate and maintain the documents necessary for product fabrication, (2) communicate the information contained in these documents to the production floor, and (3) obtain quality assurance and manufacturing feedback information from the production floor. The purpose of this paper is to describe the various components of the CAPPP system and explain their applicability to product fabrication, specifically quality assurance functions

  3. Utility/Manufacturers Robots Users Group: a partnership promoting the applications of robots in all utility industries

    International Nuclear Information System (INIS)

    Meieran, H.B.; Roman, H.T.

    1988-01-01

    The purpose of this presentation is to describe the roles and the goals of the recently established Utility/Manufacturers Robots Users Group (U/M RUG), an organization which is dedicated to promoting the employment of robots in all utility facilities. This group is composed of volunteer representatives from the utilities, robot manufacturers, service organizations/consulting groups, academia, national and non-government funding agencies, and national laboratories. Although the Group primarily serves as a forum and a guide for technology transfer, exchanging ideas, and promoting philosophies of applications among its members, it also provides this type of assistance to external groups and agencies. (author)

  4. Application of virtual surgical planning with computer assisted design and manufacturing technology to cranio-maxillofacial surgery.

    Science.gov (United States)

    Zhao, Linping; Patel, Pravin K; Cohen, Mimis

    2012-07-01

    Computer aided design and manufacturing (CAD/CAM) technology today is the standard in manufacturing industry. The application of the CAD/CAM technology, together with the emerging 3D medical images based virtual surgical planning (VSP) technology, to craniomaxillofacial reconstruction has been gaining increasing attention to reconstructive surgeons. This article illustrates the components, system and clinical management of the VSP and CAD/CAM technology including: data acquisition, virtual surgical and treatment planning, individual implant design and fabrication, and outcome assessment. It focuses primarily on the technical aspects of the VSP and CAD/CAM system to improve the predictability of the planning and outcome.

  5. Evaluation of low-residue soldering for military and commercial applications: A report from the Low-Residue Soldering Task Force

    Energy Technology Data Exchange (ETDEWEB)

    Iman, R.L.; Anderson, D.J. [Sandia National Labs., Albuquerque, NM (United States); Burress, R.V. [SEHO (United States)] [and others

    1995-06-01

    The LRSTF combined the efforts of industry, military, and government to evaluate low-residue soldering processes for military and commercial applications. These processes were selected for evaluation because they provide a means for the military to support the presidential mandate while producing reliable hardware at a lower cost. This report presents the complete details and results of a testing program conducted by the LRSTF to evaluate low-residue soldering for printed wiring assemblies. A previous informal document provided details of the test plan used in this evaluation. Many of the details of that test plan are contained in this report. The test data are too massive to include in this report, however, these data are available on disk as Excel spreadsheets upon request. The main purpose of low-residue soldering is to eliminate waste streams during the manufacturing process.

  6. Application of statistics to VLSI circuit manufacturing : test, diagnosis, and reliability

    NARCIS (Netherlands)

    Krishnan, Shaji

    2017-01-01

    Semiconductor product manufacturing companies strive to deliver defect free, and reliable products to their customers. However, with the down-scaling of technology, increasing the throughput at every stage of semiconductor product manufacturing becomes a harder challenge. To avoid process-related

  7. 77 FR 47115 - Manufacturer of Controlled Substances; Notice of Application; Cayman Chemical Company

    Science.gov (United States)

    2012-08-07

    ...)-propylthiophenethylamine I (7348). Marihuana (7360) I Tetrahydrocannabinols (7370) I Mescaline (7381) I 3,4,5... (1205) II The company plans to manufacture small quantities of marihuana derivatives for research purposes. In reference to drug code 7360 (Marihuana), the company plans to bulk manufacture cannabidiol. In...

  8. Some problems of manufacturing and industrial application of CoMo-Al2O3 catalyst

    International Nuclear Information System (INIS)

    Walendziewski, J.

    1991-01-01

    The monograph presents results of studies of some selected problems relating to CoMo-Al 2 O 3 catalyst: method of production alumina support and catalyst; application of catalyst in the selected hydro refining processes; physicochemical properties of the used catalyst; reclamation of metal compounds from the spent catalyst. Results of investigations of catalyst preparation illustrate how the physicochemical properties of alumina support and catalyst, mainly porous structure could be controlled by the selection of raw materials and parameters of aluminum hydroxide precipitation, method of forming and calcination temperature of support. Application of the catalyst of modified porous structure has shown its high activity in hydro refining process of light cracking catalytic oil (over 95% hydrodesulphurization) and mild hydro cracking process of vacuum gas oil (sulphur content in product below 0.03% wt.). As an effect of studying of hydro refining process of aromatic hydrocarbon fraction it has been found that H 2 S concentration in reaction mixture is the main factor influencing process selectivity. Some effect on the selectivity exerts also other process parameters and chemical composition of the catalyst - cobalt molybdenum content ratio and promoters content. Long term exploitation of the domestic CoMo-Al 2 O 3 catalyst in hydrodesulphurization process indicates its satisfied thermal stability although results in deteriorating of mechanical resistance, lowering of specific surface area, increase in mean pore radius and decrease in acidity of catalyst. In the last chapter of the monograph the results of investigations of reclamation of metal compounds (molybdic acid, aluminum hydroxide, cobalt carbonate) from the spent catalyst as well as an original technology of manufacture of the fresh one using these compounds have been presented. (author). 338 refs, 31 figs, 32 tabs

  9. Micro-manufacturing technologies and their applications a theoretical and practical guide

    CERN Document Server

    Shipley, David

    2017-01-01

    This book provides in-depth theoretical and practical information on recent advances in micro-manufacturing technologies and processes, covering such topics as micro-injection moulding, micro-cutting, micro-EDM, micro-assembly, micro-additive manufacturing, moulded interconnected devices, and microscale metrology. It is designed to provide complementary material for the related e-learning platform on micro-manufacturing developed within the framework of the Leonardo da Vinci project 2013-3748/542424: MIMAN-T: Micro-Manufacturing Training System for SMEs. The book is mainly addressed to technicians and prospective professionals in the sector and will serve as an easily usable tool to facilitate the translation of micro-manufacturing technologies into tangible industrial benefits. Numerous examples are included to assist readers in learning and implementing the described technologies. In addition, an individual chapter is devoted to technological foresight, addressing market analysis and business models for mic...

  10. Digimarc MediaBridge: the birth of a consumer product from concept to commercial application

    Science.gov (United States)

    Perry, Burt; MacIntosh, Brian; Cushman, David

    2002-04-01

    This paper examines the issues encountered in the development and commercial deployment of a system based on digital watermarking technology. The paper provides an overview of the development of digital watermarking technology and the first applications to use the technology. It also looks at how we took the concept of digital watermarking as a communications channel within a digital environment and applied it to the physical print world to produce the Digimarc MediaBridge product. We describe the engineering tradeoffs that were made to balance competing requirements of watermark robustness, image quality, embedding process, detection speed and end user ease of use. Today, the Digimarc MediaBridge product links printed materials to auxiliary information about the content, via the Internet, to provide enhanced informational marketing, promotion, advertising and commerce opportunities.

  11. KrF laser cost/performance model for ICF commercial applications

    International Nuclear Information System (INIS)

    Harris, D.B.; Pendergrass, J.H.

    1985-01-01

    Simple expressions suitable for use in commercial-applications plant parameter studies for the direct capital cost plus indirect field costs and for the efficiency as a function of repetition rate were developed for pure-optical-compression KrF laser fusion drivers. These simple expressions summarize estimates obtained from detailed cost-performance studies incorporating recent results of ongoing physics, design, and cost studies. Contributions of KrF laser capital charges and D and M costs to total levelized constant-dollar (1984) unit ICF power generation cost are estimated as a function of plant size and driver pulse energy using a published gain for short-wavelength lasers and representative values of plant parameters

  12. Severe Plastic Deformation of Commercial Pure Titanium (CP-Ti) for Biomedical Applications: A Brief Review

    Science.gov (United States)

    Mahmoodian, Reza; Annuar, N. Syahira M.; Faraji, Ghader; Bahar, Nadia Dayana; Razak, Bushroa Abd; Sparham, Mahdi

    2017-11-01

    This paper reviews severe plastic deformation (SPD) techniques for producing ultrafine-grained (UFG) and nanostructured commercial pure titanium (CP-Ti) for biomedical applications as the best alternative to titanium alloys. SPD processes, effective parameters, and advantages of nanostructured CP-Ti over coarse-grained (CG) material and Ti alloys are briefly reviewed. It is reported that nanostructured CP-Ti processed via SPD exhibits higher mechanical strength comparable to Ti alloys but better biological response and superior biocompatibility. Also, different surface modification techniques offer different results on UFG and CG CP-Ti, leading to nanoscale surface topography in UFG samples. Overall, it is reported that nanostructured CP-Ti processed by SPD could be considered to be the best candidate for biomedical implants.

  13. Radiation tolerance study of a commercial 65 nm CMOS technology for high energy physics applications

    Energy Technology Data Exchange (ETDEWEB)

    Ding, Lili, E-mail: lili03.ding@gmail.com [Department of Information Engineering, Padova University, Via Gradenigo 6/B, 35131 Padova (Italy); INFN, Padova, Via Marzolo 8, 35131 Padova (Italy); State Key Laboratory of Pulsed Radiation Simulation and Effect, Northwest Institute of Nuclear Technology, Xi' an (China); Gerardin, Simone [Department of Information Engineering, Padova University, Via Gradenigo 6/B, 35131 Padova (Italy); INFN, Padova, Via Marzolo 8, 35131 Padova (Italy); Bagatin, Marta [Department of Information Engineering, Padova University, Via Gradenigo 6/B, 35131 Padova (Italy); Bisello, Dario [Department of Physics and Astronomy, Padova University, Via Marzolo 8, 35131 Padova (Italy); INFN, Padova, Via Marzolo 8, 35131 Padova (Italy); Mattiazzo, Serena [Department of Physics and Astronomy, Padova University, Via Marzolo 8, 35131 Padova (Italy); Paccagnella, Alessandro [Department of Information Engineering, Padova University, Via Gradenigo 6/B, 35131 Padova (Italy); INFN, Padova, Via Marzolo 8, 35131 Padova (Italy)

    2016-09-21

    This paper reports the radiation tolerance study of a commercial 65 nm technology, which is a strong candidate for the Large Hadron Collider applications. After exposure to 3 MeV protons till 1 Grad dose, the 65 nm CMOS transistors, especially the pMOSFETs, showed severe long-term degradation mainly in the saturation drain currents. There were some differences between the degradation levels in the nMOSFETs and the pMOSFETs, which were likely attributed to the positive charges trapped in the gate spacers. After exposure to heavy ions till multiple strikes, the pMOSFETs did not show any sudden loss of drain currents, the degradations in the characteristics were negligible.

  14. Catalog of Realizations for DXCCII using Commercially Available ICs and Applications

    Directory of Open Access Journals (Sweden)

    S. Maheshwari

    2012-04-01

    Full Text Available This paper presents fifteen distinct practical realizations for dual-X second generation current conveyor (DXCCII using commercially available integrated circuits. Detailed comparisons and results are presented to verify the utility of proposed realizations. The catalog of proposed realizations is a first attempt and is expected to be useful for testing newly developed circuits based on dual-X second generation current conveyor. Each of the first fourteen proposed realizations uses four ICs. One three IC based implementation is further given making the total count fifteen. Some additional features are also explored which further enhance the versatility of DXCCII. The paper further presents a novel and compact quadrature oscillator to verify the applicability of the proposed realizations. Single resistance control of the frequency of oscillation is also demonstrated by employing the new gain-variable DXCCII. Experimental results are also included along with simulation results to validate the proposed theory and its practical significance.

  15. Modification of polysaccharides: Pharmaceutical and tissue engineering applications with commercial utility (patents)

    Energy Technology Data Exchange (ETDEWEB)

    Malviya, Rishabha, E-mail: rishabhamalviya19@gmail.com [Polymer Science Laboratory, Department of Pharmacy, School of Medical & Allied Sciences, Galgotias University, Greator Noida, UP (India); Department of Pharmacy, Uttarkhand Technical University, Dehradun, Uttarkhand (India); Sharma, Pramod Kumar [Polymer Science Laboratory, Department of Pharmacy, School of Medical & Allied Sciences, Galgotias University, Greator Noida, UP (India); Dubey, Susheel Kumar [Siddarth Institute of Pharmacy, Dehradun, Uttarkhand (India)

    2016-11-01

    Polymer modifications open new era for the development of polymers with requisite properties. Use of modified polymers is practically boundless. Different studies focus on biomedical applications of chemically modified polysaccharides. Development and utilization of modified polysaccharides get attention to be used as carrier for pharmaceutical drug delivery as well as tissue engineering scaffolds. Grafted polymer shows better cellular regeneration, signal transmission, diagnostic and imaging material than putative form. This review article aims to discuss various approaches to modify naturally derived polymer and their applications as pharmaceutical drug carrier and as a material for wound dressing and artificial cartilage due to better biophysical cues. Manuscript included various patents based on the applications of modified polymers and techniques used to modify polymers. - Highlights: • Properties of natural polysaccharides can be modulated by modification in their basic backbone. • Polysaccharides can be easily modified using microwave irradiation as compared to conventional closed vessel modification. • Biodegradable and biocompatible nature of modified polymer promotes their use in targeted cellular delivery of pharmaceuticals. • Studies show strong support that biodegradable polymers have ability to modulate cell signaling, cellular attachment, migration, proliferation and differentiation. • Manuscript reveals the fact that various commercial patents have been granted for the use of modified polymer.

  16. Hardness variability in commercial technologies

    International Nuclear Information System (INIS)

    Shaneyfelt, M.R.; Winokur, P.S.; Meisenheimer, T.L.; Sexton, F.W.; Roeske, S.B.; Knoll, M.G.

    1994-01-01

    The radiation hardness of commercial Floating Gate 256K E 2 PROMs from a single diffusion lot was observed to vary between 5 to 25 krad(Si) when irradiated at a low dose rate of 64 mrad(Si)/s. Additional variations in E 2 PROM hardness were found to depend on bias condition and failure mode (i.e., inability to read or write the memory), as well as the foundry at which the part was manufactured. This variability is related to system requirements, and it is shown that hardness level and variability affect the allowable mode of operation for E 2 PROMs in space applications. The radiation hardness of commercial 1-Mbit CMOS SRAMs from Micron, Hitachi, and Sony irradiated at 147 rad(Si)/s was approximately 12, 13, and 19 krad(Si), respectively. These failure levels appear to be related to increases in leakage current during irradiation. Hardness of SRAMs from each manufacturer varied by less than 20%, but differences between manufacturers are significant. The Qualified Manufacturer's List approach to radiation hardness assurance is suggested as a way to reduce variability and to improve the hardness level of commercial technologies

  17. Implementation of manufacturing data management application in the scientific research project. Case: CERN, the European Organization for Nuclear Research

    CERN Document Server

    Saifoulina, Margarita

    2010-01-01

    This Bachelor’s thesis examined the implementation process of an MTF (Manufacturing and Test Folder) application in the CLIC (Compact Linear Collider) Radio Frequency Structure Development project for manufacturing data management purposes. The primary goal of the study was to investigate how MTF implementation and its integration with CERN EDMS (Engineering and Equipment Data Management System) system could facilitate product life cycle through the supply chain, and could affect on manufacturing operations performance in internaland external levels. The aim of the study was also to find out implementation differences within CERN (European Organization for Nuclear Research) projects. The study is divided into two parts: a qualitative theory section and an empirical section. In the theory section differences of features between PDM (Product Data Management), EDM (Engineering Data Management) and PLM (Product Life Cycle Management) systems were studied. The thesis examined the benefits and managerial challeng...

  18. New Sunshine Program for fiscal 2000. Development of photovoltaic power system commercialization technology (Development of ultrahigh-efficiency crystalline compound solar cell manufacturing technology - Surveys and studies of peripheral key technologies/Surveys of ultrahigh-efficiency solar cell application fields); 2000 nendo New sunshine keikaku seika hokokusho. Taiyoko hatsuden system jitsuyoka gijutsu kaihatsu - Chokokoritsu kessho kagobutsu taiyo denchi no seizo gijutsu kaihatsu, Shuhen yoso gijutsu ni kansuru chosa kenkyu (Chokokoritsu taiyo denchi tou oyo bunya kaitaku chosa)

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2001-03-01

    Surveys and studies were conducted in order to make propositions concerning the fields of application wherein the merits of ultrahigh-efficiency solar cells would be fully utilized. A questionnaire was held about solar cell application fields, and studies were made about new systems based on the need in the market for specific solar cell goods and capable of supporting their mass diffusion. Proposed as the result was the establishment of a rental (lease) system for photovoltaic power systems, a local photovoltaics advisory system, a market for used photovoltaic power systems, and so forth. In the feasibility study of photovoltaic power generation on unused land in agricultural villages, surveys were conducted concerning energy problems, the energy structure, the actual state of energy consumption, the abandoned farm and its utilization, and so forth. Propositions involving photovoltaic power feasibility were then made, which covered power consumption for greenhouse culture, energy supply for producing methanol out of biomass, power sources for insect incapacitating yellow fluorescent lamps, power sources for livestock barn air-conditioning, power sources for animal excretion treatment, and so forth. (NEDO)

  19. A study on the applications of AI in finishing of additive manufacturing parts

    Science.gov (United States)

    Fathima Patham, K.

    2017-06-01

    Artificial intelligent and computer simulation are the technological powerful tools for solving complex problems in the manufacturing industries. Additive Manufacturing is one of the powerful manufacturing techniques that provide design flexibilities to the products. The products with complex shapes are directly manufactured without the need of any machining and tooling using Additive Manufacturing. However, the main drawback of the components produced using the Additive Manufacturing processes is the quality of the surfaces. This study aims to minimize the defects caused during Additive Manufacturing with the aid of Artificial Intelligence. The developed AI system has three layers, each layer is trying to eliminate or minimize the production errors. The first layer of the AI system optimizes the digitization of the 3D CAD model of the product and hence reduces the stair case errors. The second layer of the AI system optimizes the 3D printing machine parameters in order to eliminate the warping effect. The third layer of AI system helps to choose the surface finishing technique suitable for the printed component based on the Degree of Complexity of the product and the material. The efficiency of the developed AI system was examined on the functional parts such as gears.

  20. Application of a risk analysis method to different technologies for producing a monoclonal antibody employed in hepatitis B vaccine manufacturing.

    Science.gov (United States)

    Milá, Lorely; Valdés, Rodolfo; Tamayo, Andrés; Padilla, Sigifredo; Ferro, Williams

    2012-03-01

    CB.Hep-1 monoclonal antibody (mAb) is used for a recombinant Hepatitis B vaccine manufacturing, which is included in a worldwide vaccination program against Hepatitis B disease. The use of this mAb as immunoligand has been addressed into one of the most efficient steps of active pharmaceutical ingredient purification process. Regarding this, Quality Risk Management (QRM) provides an excellent framework for the risk management use in pharmaceutical manufacturing and quality decision-making applications. Consequently, this study sought applying a prospective risk analysis methodology Failure Mode Effects Analysis (FMEA) as QRM tool for analyzing different CB.Hep-1 mAb manufacturing technologies. As main conclusions FMEA was successfully used to assess risks associated with potential problems in CB.Hep-1 mAb manufacturing processes. The severity and occurrence of risks analysis evidenced that the percentage of very high severe risks ranged 31.0-38.7% of all risks and the huge majority of risks have a very low occurrence level (61.9-83.3%) in all assessed technologies. Finally, additive Risk Priority Number, was descending ordered as follow: transgenic plants (2636), ascites (2577), transgenic animals (2046) and hollow fiber bioreactors (1654), which also corroborated that in vitro technology, should be the technology of choice for CB.Hep-1 mAb manufacturing in terms of risks and mAb molecule quality. Copyright © 2011 The International Alliance for Biological Standardization. Published by Elsevier Ltd. All rights reserved.

  1. Application Of Artificial Neural Networks In Modeling Of Manufactured Front Metallization Contact Resistance For Silicon Solar Cells

    Directory of Open Access Journals (Sweden)

    Musztyfaga-Staszuk M.

    2015-09-01

    Full Text Available This paper presents the application of artificial neural networks for prediction contact resistance of front metallization for silicon solar cells. The influence of the obtained front electrode features on electrical properties of solar cells was estimated. The front electrode of photovoltaic cells was deposited using screen printing (SP method and next to manufactured by two methods: convectional (1. co-fired in an infrared belt furnace and unconventional (2. Selective Laser Sintering. Resistance of front electrodes solar cells was investigated using Transmission Line Model (TLM. Artificial neural networks were obtained with the use of Statistica Neural Network by Statsoft. Created artificial neural networks makes possible the easy modelling of contact resistance of manufactured front metallization and allows the better selection of production parameters. The following technological recommendations for the screen printing connected with co-firing and selective laser sintering technology such as optimal paste composition, morphology of the silicon substrate, co-firing temperature and the power and scanning speed of the laser beam to manufacture the front electrode of silicon solar cells were experimentally selected in order to obtain uniformly melted structure well adhered to substrate, of a small front electrode substrate joint resistance value. The prediction possibility of contact resistance of manufactured front metallization is valuable for manufacturers and constructors. It allows preserving the customers’ quality requirements and bringing also measurable financial advantages.

  2. A Manufacturing Cost and Supply Chain Analysis of SiC Power Electronics Applicable to Medium-Voltage Motor Drives

    Energy Technology Data Exchange (ETDEWEB)

    Horowitz, Kelsey [National Renewable Energy Lab. (NREL), Golden, CO (United States); Remo, Timothy [National Renewable Energy Lab. (NREL), Golden, CO (United States); Reese, Samantha [National Renewable Energy Lab. (NREL), Golden, CO (United States)

    2017-03-24

    Wide bandgap (WBG) semiconductor devices are increasingly being considered for use in certain power electronics applications, where they can improve efficiency, performance, footprint, and, potentially, total system cost compared to systems using traditional silicon (Si) devices. Silicon carbide (SiC) devices in particular -- which are currently more mature than other WBG devices -- are poised for growth in the coming years. Today, the manufacturing of SiC wafers is concentrated in the United States, and chip production is split roughly equally between the United States, Japan, and Europe. Established contract manufacturers located throughout Asia typically carry out manufacturing of WBG power modules. We seek to understand how global manufacturing of SiC components may evolve over time by illustrating the regional cost drivers along the supply chain and providing an overview of other factors that influence where manufacturing is sited. We conduct this analysis for a particular case study where SiC devices are used in a medium-voltage motor drive.

  3. 270GHz SiGe BiCMOS manufacturing process platform for mmWave applications

    Science.gov (United States)

    Kar-Roy, Arjun; Preisler, Edward J.; Talor, George; Yan, Zhixin; Booth, Roger; Zheng, Jie; Chaudhry, Samir; Howard, David; Racanelli, Marco

    2011-11-01

    TowerJazz has been offering the high volume commercial SiGe BiCMOS process technology platform, SBC18, for more than a decade. In this paper, we describe the TowerJazz SBC18H3 SiGe BiCMOS process which integrates a production ready 240GHz FT / 270 GHz FMAX SiGe HBT on a 1.8V/3.3V dual gate oxide CMOS process in the SBC18 technology platform. The high-speed NPNs in SBC18H3 process have demonstrated NFMIN of ~2dB at 40GHz, a BVceo of 1.6V and a dc current gain of 1200. This state-of-the-art process also comes with P-I-N diodes with high isolation and low insertion losses, Schottky diodes capable of exceeding cut-off frequencies of 1THz, high density stacked MIM capacitors, MOS and high performance junction varactors characterized up to 50GHz, thick upper metal layers for inductors, and various resistors such as low value and high value unsilicided poly resistors, metal and nwell resistors. Applications of the SBC18H3 platform for millimeter-wave products for automotive radars, phased array radars and Wband imaging are presented.

  4. Prize for Industrial Applications of Physics: Reflective Cholesteric Liquid Crystals - Innovations in Materials, Display Technology, and Commercialization

    Science.gov (United States)

    Khan, Asad

    Reflective Cholesteric Liquid Crystals have been the subject of much research, development, and commercialization - in display technology as well as other embodiments, such as sensors, privacy films, etc. The liquid Crystal Institute (LCI) at Kent State University (KSU) served as a hot bed of much of the research and development in this field in the early 1990's. From here, the reflective technology was licensed to Kent Displays (KDI) to further develop and commercialize. The 90's saw some development in flexible technologies, drive scheme, display design, as well as materials. The early part of the century took a turn with a strong effort in encapsulation based flexible display development. In 2006, KDI engineers and technologists started firming up ambitious plans for the world's first roll-to-roll manufacturing line for bistable cholesteric displays. In 2009, this became a reality! In early 2010, the first eWriter product was launched into the consumer market under the brand Boogie Board®. Within months, this became a success forcing the rapid development of the manufacturing process for the flexible displays. Today, the company has two manufacturing lines, 24 hour roll-to-roll production of flexible displays, millions of Boogie Board products in the global market place, and a growing OEM business in the Boogie Board technology. KDI continues to do basic research, development, and exploration in the bistable display field. It also has had to become an expert in the supply chain management of the unique raw materials needed for flexible display manufacturing, while still managing global operations with sales offices in several continents and a growing and diversified group of individuals. In this presentation, we will present the story, research, development, technology, and latest trends in bistable cholesteric liquid crystal materials with a particular emphasis on the eWriter technology and market.

  5. One-step manufacturing of innovative flat-knitted 3D net-shape preforms for composite applications

    Science.gov (United States)

    Bollengier, Quentin; Wieczorek, Florian; Hellmann, Sven; Trümper, Wolfgang; Cherif, Chokri

    2017-10-01

    Mostly due to the cost-intensive manually performed processing operations, the production of complex-shaped fibre reinforced plastic composites (FRPC) is currently very expensive and therefore either restricted to sectors with high added value or for small batch applications (e.g. in the aerospace or automotive industry). Previous works suggest that the successful integration of conventional textile manufacturing processes in the FRPC-process chain is the key to a cost-efficient manufacturing of complex three-dimensional (3D) FRPC-components with stress-oriented fibre arrangement. Therefore, this work focuses on the development of the multilayer weft knitting technology for the one-step manufacturing of complex 3D net-shaped preforms for high performance FRPC applications. In order to highlight the advantages of net-shaped multilayer weft knitted fabrics for the production of complex FRPC parts, seamless preforms such as 3D skin-stringer structures and tubular fabrics with load oriented fibre arrangement are realised. In this paper, the development of the textile bindings and performed technical modifications on flat knitting machines are presented. The results show that the multilayer weft knitting technology meets perfectly the requirements for a fully automated and reproducible manufacturing of complex 3D textile preforms with stress-oriented fibre arrangement.

  6. Advantages of utilizing DMD based rapid manufacturing systems in mass customization applications

    Science.gov (United States)

    El-Siblani, A.

    2010-02-01

    The Use of DMD based Rapid Manufacturing Systems has proven to be very advantageous in the production of highly accurate plastic based components for use in mass customization market such as hearing aids, and dental markets. The voxelization process currently afforded with the DLP technology eliminates any layering effect associated with all existing additive Rapid Manufacturing technologies. The smooth accurate surfaces produced in an additive process utilizing DLP technology, through the voxelization approach, allow for the production of custom finished products. The implementation of DLP technology in rapid prototyping and rapid manufacturing systems allow for the usage of highly viscous photopolymer based liquid and paste composites for rapid manufacturing that could not be used in any other additive process prior to implementation of DLP technology in RP and RM systems. It also allowed for the greater throughput in production without sacrificing quality and accuracy.

  7. 77 FR 30327 - Manufacturer of Controlled Substances; Notice Of Application; Research Triangle Institute

    Science.gov (United States)

    2012-05-22

    ... the following basic classes of controlled substances: Drug Schedule Marihuana (7360) I Cocaine (9041) II The Institute will manufacture marihuana, and cocaine derivatives for use by their customers in...

  8. Nondestructive Testing of Additive Manufactured Metal Parts Used in Aerospace Applications

    Science.gov (United States)

    Waller, Jess M.

    2018-01-01

    NDE inspectors, QA/QE professionals, and program managers responsible for the out-sourcing, procurement, fabrication, finishing, inspection, and qualification and certification of additively manufactured (AM) parts should attend this course.

  9. [The application of two occupation health risk assessment models in a wooden furniture manufacturing industry].

    Science.gov (United States)

    Wang, A H; Leng, P B; Bian, G L; Li, X H; Mao, G C; Zhang, M B

    2016-10-20

    Objective: To explore the applicability of 2 different models of occupational health risk assessment in wooden furniture manufacturing industry. Methods: American EPA inhalation risk model and ICMM model of occupational health risk assessment were conducted to assess occupational health risk in a small wooden furniture enterprises, respectively. Results: There was poor protective measure and equipment of occupational disease in the plant. The concentration of wood dust in the air of two workshops was over occupational exposure limit (OEL) , and the C TWA was 8.9 mg/m 3 and 3.6 mg/m 3 , respectively. According to EPA model, the workers who exposed to benzene in this plant had high risk (9.7×10 -6 ~34.3×10 -6 ) of leukemia, and who exposed to formaldehyde had high risk (11.4 × 10 -6 ) of squamous cell carcinoma. There were inconsistent evaluation results using the ICMM tools of standard-based matrix and calculated risk rating. There were very high risks to be attacked by rhinocarcinoma of the workers who exposed to wood dust for the tool of calculated risk rating, while high risk for the tool of standard-based matrix. For the workers who exposed to noise, risk of noise-induced deafness was unacceptable and medium risk using two tools, respectively. Conclusion: Both EPA model and ICMM model can appropriately predict and assessthe occupational health risk in wooden furniture manufactory, ICMM due to the relatively simple operation, easy evaluation parameters, assessment of occupational - disease - inductive factors comprehensively, and more suitable for wooden furniture production enterprise.

  10. Design and manufacture of ceramic heat pipes for high temperature applications

    International Nuclear Information System (INIS)

    Meisel, Peter; Jobst, Matthias; Lippmann, Wolfgang; Hurtado, Antonio

    2015-01-01

    Heat exchangers based on ceramic heat pipes were designed for use under highly abrasive and corrosive atmospheres at temperatures in the range of 800–1200 °C for high-temperature power-engineering applications. The presented heat pipes are gravity assisted and based on a multi-layer concept comprising a ceramic cladding and an inner metal tube that contains sodium as the working fluid. Hermetical encapsulation of the working fluid was achieved by electron-beam welding of the inner metal tube. Subsequently, closure of the surrounding ceramic tube was performed by laser brazing technology using a glass solder. Temperature resistance and functionality of the manufactured ceramic thermosyphons could be confirmed experimentally in a hot combustion gas atmosphere at temperatures up to 1100 °C. The ceramic tubes used had an outer diameter of 22 mm and a total length of 770 mm. The measured axial heat transfer of the ceramic gravity assisted heat pipes at the stationary operating point with cold/hot gas temperature of 100 °C/900 °C was 400 W. The result of the calculation using the created mathematical model amounted to 459 W. - Highlights: • Heat-pipe design consists of a ceramic shell and an inner metallic tube. • Laser brazing technology is suitable to seal ceramic heat-pipes. • Thermal characteristic of double wall thermosyphon was modelled using FEM code. • Experimental investigations demonstrated functionality of double wall thermosyphons

  11. Development of ZIF-8 membranes: opportunities and challenges for commercial applications

    KAUST Repository

    Lai, Zhiping

    2018-03-24

    Metal organic framework (MOF) membranes have attracted significant attentions in recent years because of their potentials in gas and liquid separations and other applications such as catalysis and chemical sensors, etc. More than half of the MOF membrane publications up to date are related to ZIF-8 system, because of its easy synthesis, relatively high stability, and excellent gas separation performance, which allows many novel ideas to be easily implemented. Extensive studies have shown that ZIF-8 membranes hold great potentials in gas separations, but may face great challenges in liquid separations mainly because of their poor stability. This is also a common observation for other MOF membranes. As such, in this article we use ZIF-8 membrane as a prototype and focus on its development in gas separations for the discussions of the most concerned issues related to membrane commercialization including membrane synthesis, separation performance, stability, process reproducibility, and finally on the opportunities and challenges that MOF membranes may face in industrial applications.

  12. Development of ZIF-8 membranes: opportunities and challenges for commercial applications

    KAUST Repository

    Lai, Zhiping

    2018-01-01

    Metal organic framework (MOF) membranes have attracted significant attentions in recent years because of their potentials in gas and liquid separations and other applications such as catalysis and chemical sensors, etc. More than half of the MOF membrane publications up to date are related to ZIF-8 system, because of its easy synthesis, relatively high stability, and excellent gas separation performance, which allows many novel ideas to be easily implemented. Extensive studies have shown that ZIF-8 membranes hold great potentials in gas separations, but may face great challenges in liquid separations mainly because of their poor stability. This is also a common observation for other MOF membranes. As such, in this article we use ZIF-8 membrane as a prototype and focus on its development in gas separations for the discussions of the most concerned issues related to membrane commercialization including membrane synthesis, separation performance, stability, process reproducibility, and finally on the opportunities and challenges that MOF membranes may face in industrial applications.

  13. Image Analysis via Soft Computing: Prototype Applications at NASA KSC and Product Commercialization

    Science.gov (United States)

    Dominguez, Jesus A.; Klinko, Steve

    2011-01-01

    This slide presentation reviews the use of "soft computing" which differs from "hard computing" in that it is more tolerant of imprecision, partial truth, uncertainty, and approximation and its use in image analysis. Soft computing provides flexible information processing to handle real life ambiguous situations and achieve tractability, robustness low solution cost, and a closer resemblance to human decision making. Several systems are or have been developed: Fuzzy Reasoning Edge Detection (FRED), Fuzzy Reasoning Adaptive Thresholding (FRAT), Image enhancement techniques, and visual/pattern recognition. These systems are compared with examples that show the effectiveness of each. NASA applications that are reviewed are: Real-Time (RT) Anomaly Detection, Real-Time (RT) Moving Debris Detection and the Columbia Investigation. The RT anomaly detection reviewed the case of a damaged cable for the emergency egress system. The use of these techniques is further illustrated in the Columbia investigation with the location and detection of Foam debris. There are several applications in commercial usage: image enhancement, human screening and privacy protection, visual inspection, 3D heart visualization, tumor detections and x ray image enhancement.

  14. Applicability of chemical vapour polishing of additive manufactured parts to meet production-quality

    DEFF Research Database (Denmark)

    Pedersen, D. B.; Hansen, H. N.; Nielsen, J. S.

    2014-01-01

    The Fused Deposition Modelling (FDM) method is the most rapidly growing Additive Manufacturing (AM) method[1]. FDM employs a 2.5D deposition scheme which induce a step-ladder shaped surface definition [2], with seams of the individual layers clearly visible[3]. This paper investigate to which...... of FDM manufactured parts can be taken from their current quality into the precision engineering domain....

  15. A case study analysis of the application of design for manufacture principles by industrial design students

    OpenAIRE

    Marshall, R; Page, T

    2016-01-01

    This paper describes a case study evaluation of a module that engages students on product and industrial design programmes with the principles of Design for Manufacturing (DFM). The primary element of the module is to expose students to the constraints of a full design to manufacture process. The module explores the design of a small polymer promotional item, together with the means of mass producing that item. This is done through the process of injection moulding and students design an inje...

  16. Development and application of high-precision laser welding technology for manufacturing Ti alloy frames of glasses

    International Nuclear Information System (INIS)

    Kim, S. S.; Yang, M. S.; Kim, W. K.; Lee, D. Y.; Kim, J. M.; Leem, B. C.; Shin, J. S.; Lee, D. H.

    1999-12-01

    The research and development efforts of the high precision laser welding technology for manufacturing titanium alloy frames of glasses. For this purpose, laser welding device with the high beam quality is designed and fabricated, which consists of a optical fiber transmission part, a welding monitoring part and a welding controller. The welding nozzle and holding fixtures for manufacturing titanium and shape memory alloy frames of glasses. Titanium and shape memory alloy frames of glasses to be developed were experimentally manufactured by utilizing the laser welding using the optical fiber of GI 400 μm. As a result, the seam welding with the bead width of 0.3 mm or less and the weld penetration of 0.3-0.4mm could be accomplished. The fundamental technology was established through design of welding jigs with a variety of configurations and adequate welding conditions. Also, for the purpose to enable the companies participating in this project to commercialize the developed technology acceleratedly, a training program for the engineers belonging to such companies was conducted along with the technology transfer through joint experiments with the engineers. (author)

  17. Application of response surface methodology to maximize the productivity of scalable automated human embryonic stem cell manufacture.

    Science.gov (United States)

    Ratcliffe, Elizabeth; Hourd, Paul; Guijarro-Leach, Juan; Rayment, Erin; Williams, David J; Thomas, Robert J

    2013-01-01

    Commercial regenerative medicine will require large quantities of clinical-specification human cells. The cost and quality of manufacture is notoriously difficult to control due to highly complex processes with poorly defined tolerances. As a step to overcome this, we aimed to demonstrate the use of 'quality-by-design' tools to define the operating space for economic passage of a scalable human embryonic stem cell production method with minimal cell loss. Design of experiments response surface methodology was applied to generate empirical models to predict optimal operating conditions for a unit of manufacture of a previously developed automatable and scalable human embryonic stem cell production method. Two models were defined to predict cell yield and cell recovery rate postpassage, in terms of the predictor variables of media volume, cell seeding density, media exchange and length of passage. Predicted operating conditions for maximized productivity were successfully validated. Such 'quality-by-design' type approaches to process design and optimization will be essential to reduce the risk of product failure and patient harm, and to build regulatory confidence in cell therapy manufacturing processes.

  18. COTS low-cost 622-Mb/s free-space laser communications link for short-distance commercial applications

    Science.gov (United States)

    Morrison, Kenneth A.

    2000-05-01

    The results from a low cost 622 Mb/s, free-space laser communication link operating at 850 nm for short distance commercial applications is presented. The test results demonstrate the use of a free-space laser communications transceiver for building to building applications such as LAN, WAN and ATM operations, etc. This illustrates the potential for wide-use commercial computer network applications. The transceiver is constructed of commercial off-the-shelf materials for the development of a low-cost laser communications data link. The test system configuration utilizes standard Personal Computers with network cards and signal conversion cards for the copper to optical medical conversion. These tests precede the development of an increased data rate device operating at 2.5 Gb/s.

  19. Experimental performance evaluation for a carbon dioxide light commercial cooling application under transcritical and subcritical conditions

    International Nuclear Information System (INIS)

    Boccardi, G.; Calabrese, N.; Celata, G.P.; Mastrullo, R.; Mauro, A.W.; Perrone, A.; Trinchieri, R.

    2013-01-01

    CO 2 is one of the most interesting non toxic, nor flammable, low GWP natural fluid to be used in applications with a large direct contribution to global warming, such as vending machines. In this paper the results of an experimental investigation on a small capacity, air-forced refrigerating plant working with CO 2 are presented. The air inlet temperatures at gas cooler and evaporator were varied between 16 °C and 31 °C and between −25 °C and 25 °C, respectively, to cover the range of temperatures under conditions typical of commercial refrigeration, during quasi-steady operation. The thermodynamic analysis of the system performance was carried on varying independently the pressure at the gas cooler, by overfeeding the liquid receiver to point out the effect of refrigerant charge. The results allow to describe the performance of the system in a map varying the boundary conditions; at the same time the corresponding variations of the thermodynamic cycle, the COP and the mass flow rate are reported. -- Highlights: ► A light commercial refrigerating plant working with CO 2 was tested in order to evaluate its performance. ► 71 experimental points were collected varying the flow rates, the temperatures of air sources and the refrigerant charge. ► Mass flow rate, cooling capacity, electrical power and COP were evaluated as a function of pressures and superheating. ► The segregate influence of each operating parameter on each performance indicator was calculated. ► A map of plant performance as a function of air source temperatures is reported

  20. Application of geographical information systems for the optimal location of a commercial network

    Directory of Open Access Journals (Sweden)

    Vicente Rodríguez

    2017-07-01

    Full Text Available Purpose - The purpose of this paper is to study the optimization of the geographical location of a network of points of sale, so that each retailer can have access to a potential geographic market. In addition, the authors study the importance of the distance variable in the commercial viability of a point of sale and a network of points of sale, analysing if the best location for each point (local optimum is always the best location for the whole (global optimum. Design/methodology/approach - Location-allocation models are applied using p-median algorithms and spatial competition maximization to analyse the actual journeys of 64,740 car buyers in 1240 postal codes using a geographic information system (GIS and geomarketing techniques. Findings - The models show that the pursuit of individual objectives by each concessionaire over the collective provides poorer results for the whole network of points of sale when compared to coordinated competition. The solutions provided by the models considering geographic and marketing criteria permit a reduction in the length of journeys made by the buyers. GIS allows the optimal control of market demand coverage through the collaborative strategies of the supplying retailers, in this case, car dealerships. Originality/value - The paper contributes to the joint research of geography and marketing from a theoretical and practical point of view. The main contribution is the use of information on actual buyer journeys for the optimal location of a network of points of sale. This research also contributes to the analysis of the correlation between the optimum local and optimum global locations of a commercial network and is a pioneering work in the application of these models to the automotive sector in the territorial area of the study.

  1. Comparison of the applicability of commercial computer programs to study the thermodynamic stability of metal oxides

    International Nuclear Information System (INIS)

    Koukkari, P.; Olin, M.; Laitinen, T.; Sippola, H.

    1999-04-01

    The oxide films formed on primary circuit surfaces incorporate radioactive species from the coolant and influence different corrosion phenomena in nuclear power plants. One approach to improve the understanding on the formation and properties of these oxide films is to evaluate their thermodynamic stability. The aim of this work was to compare and demonstrate the applicability of different commercial thermodynamic computer programs to model the deposition of oxides containing iron, chromium and/or nickel in various nuclear power plant environments. The programs considered in this evaluation comprised the EQ3/6 program and a product group including such products as ChemSage, HSC (including SOLGASMIX and GIBBS), H+PLUS and ChemSheet. In the group the transfer of data between different products is relatively easy. The goal was to find out which programs can be applied to evaluate the stability of oxide films, but not to assess the absolute accuracy of the calculations. The evaluation was done by means of applying the programs to calculate the stability of pure and mixed oxides of iron, nickel and chromium on stainless steel both in WWER and BWR conditions at different temperatures and coolant compositions. The comparison showed that EQ3/6 is suitable for most thermodynamic calculations. EQ3/6 can be characterised as a professional tool, for which no commercial training is available. ChemSage is a versatile and reliable program, which can be well used together with HSC and H+PLUS. ChemSage is mainly a professional tool, while HSC is easier to operate by an occasional user. Commercial training and support is available for both ChemSage and HSC. ChemSheet has been designed to utilise the properties of ChemSage in a user-friendly spreadsheet environment. All the products tested calculate thermodynamic equilibrium. Thus they are suitable to characterise such conditions in which the formation of a certain phase is or becomes possible. On the other hand, the modelling of the

  2. Fiscal 2000 achievement report. Development of energy use rationalization-oriented silicon manufacturing process (Survey and study of analysis of commercialization of solar-grade silicon material manufacturing technology); 2000 nendo shin energy sangyo gijutsu sogo kaihatsu kiko kyodo kenkyu gyomu seika hokokusho. Energy shiyo gorika silicon seizo process kaihatsu (Taiyodenchiyou silicon genryo seizo gijutsu no jitsuyoka kaiseki ni kansuru chosa kenkyu)

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2001-03-01

    The trend of technology development, problems harbored therein, trend of the market, and the like were investigated for supporting the development of technologies for the mass production and commercialization of solar-grade silicon materials. Concerning the future of production enhancement and cost reduction in the manufacture of polycrystalline silicon solar cells, studies were made from the technological viewpoint. The results are shown below. It is estimated that approximately 4,500 tons of material silicon will be necessary in 2005 and 6,500-10,700 tons in 2010. Since the melting purification method of NEDO (New Energy and Industrial Technology Development Organization) now under development step by step toward commercialization as well as the conventional source will provide the necessary amount of material silicon, it is inferred that the development of solar cells will go on without any restraint originating in the semiconductor industry. With the commercialization of the technologies so far developed and the development/commercialization of the fast-acting high-performance solar cell technology, probabilities are high that the polycrystalline silicon solar cell manufacturing cost in 2010 will be as low as to be on the 100 yen/W (93-118 yen/W) level which is the level now held up as the goal. (NEDO)

  3. Procedure for the qualification of a manufacturer of ingot iron pieces for application in nuclear power plant components

    International Nuclear Information System (INIS)

    Rahn, K.M.M.; Jusevicius, E.; Michael, H.

    1981-01-01

    The process for the qualification of 'Sao Caetano do Sul (Acos Villares S/A)' Plant as manufacturers of ingot iron pieces for application in components of Angra 2 and Angra 3 Nuclear Power Plants, is presented. The qualification was executed by IBQN - Instituto Brasileiro de Qualidade Nuclear - the organ officially in charge of the execution of qualification of suppliers of materials for the nuclear industry. (E.G.) [pt

  4. Manufacturing and characterisation of SiC-fibre-reinforced copper in heat sink applications

    International Nuclear Information System (INIS)

    Kimmig, Stefan

    2013-01-01

    The wall materials in future fusion reactors will be operating under extreme thermal and mechanical load conditions. The divertor region of such a device is the most severely loaded component. This part is exposed to heat fluxes of up to 15 MW m 2 due to the impinging plasma particle flux. Tungsten is currently considered as the best choice for the plasmafacing-materials (PFM) in the divertor region. An efficient heat sink material is required underneath the PFM for sufficient heat transfer to the cooling channels. In the research reactor ITER a copper alloy (CuCrZr) is foreseen as heat sink material, which is able to withstand temperatures of up to 350 C, corresponding to a water coolant temperature of 150 C. For the commercial use of fusion energy an increase of the thermal efficiency is necessary by increasing the coolant temperature to over 300 C. This will cause higher stresses in the connection area between PFM and the heat sink due to different coefficients of thermal expansion combined with higher temperatures. The mechanical properties of CuCrZr are insufficient for these conditions and fibre reinforced copper metal matrix composites (CuMMC) are considered as an alternative material to strengthen the critical connection area between the heat sink and the PFM. The composite should combine the high heat conductivity of a copper matrix with the high stiffness and mechanical strength of silicon-carbide fibres (SiC-fibres). During this investigation SiC-fibres of two different production principles were studied regarding their usage for the manufacturing of a CuMMC. The main goals for the CuMMC are a tensile strength of 300 MPa combined with a heat conductivity of more than 200 W m -1 K -1 . Both of these parameters are affected by the single fibre tensile strength and by the bonding between the fibres and the copper matrix. The achievable heat conductivity in the CuMMC depends on the fibre volume ratio within the composite. Higher fibre strength reduces the

  5. Logic For Qualification And Industrialisation Of Additive Layer Manufacturing Parts For Spatial Application

    Science.gov (United States)

    Brindeau, Aymeric; Lopes, Jean-Louis; Brivot, Frederic; Bourneaud, Florent; Desagulier, Christian

    2012-07-01

    ASTRIUM Space Transportation has been manufacturing composite equipments for satellite for 25 years. For this business, the development of Additive Layer Manufacturing (ALM) processes has been identified as a real opportunity to improve design and performances. For satellite equipments, ASTRIUM ST has chosen to investigate in the Electron Beam Melting process (patented EBM® process from Arcam AB company) for the manufacturing of Titanium parts, in collaboration with MECACHROME who has developed strong skills in this ALM process. This first development step has been achieved by introducing a titanium part realised by EBM on an equipment of Atlantic Bird 7 satellite launched in September 2011. The new step consists in the formal industrialisation of the EBM process for the procurement of titanium parts for satellite equipments. The present paper describes the logic retained for this industrialisation. It includes the technical requirements but also the verifications and inspections which have to be performed to guarantee that technical requirements are met.

  6. Cement-Based Renders Manufactured with Phase-Change Materials: Applications and Feasibility

    Directory of Open Access Journals (Sweden)

    Luigi Coppola

    2016-01-01

    Full Text Available The paper focuses on the evaluation of the rheological and mechanical performances of cement-based renders manufactured with phase-change materials (PCM in form of microencapsulated paraffin for innovative and ecofriendly residential buildings. Specifically, cement-based renders were manufactured by incorporating different amount of paraffin microcapsules—ranging from 5% to 20% by weight with respect to binder. Specific mass, entrained or entrapped air, and setting time were evaluated on fresh mortars. Compressive strength was measured over time to evaluate the effect of the PCM addition on the hydration kinetics of cement. Drying shrinkage was also evaluated. Experimental results confirmed that the compressive strength decreases as the amount of PCM increases. Furthermore, the higher the PCM content, the higher the drying shrinkage. The results confirm the possibility of manufacturing cement-based renders containing up to 20% by weight of PCM microcapsules with respect to binder.

  7. [Application of occupational hazard risk index model in occupational health risk assessment in a decorative coating manufacturing enterprises].

    Science.gov (United States)

    He, P L; Zhao, C X; Dong, Q Y; Hao, S B; Xu, P; Zhang, J; Li, J G

    2018-01-20

    Objective: To evaluate the occupational health risk of decorative coating manufacturing enterprises and to explore the applicability of occupational hazard risk index model in the health risk assessment, so as to provide basis for the health management of enterprises. Methods: A decorative coating manufacturing enterprise in Hebei Province was chosen as research object, following the types of occupational hazards and contact patterns, the occupational hazard risk index model was used to evaluate occupational health risk factors of occupational hazards in the key positions of the decorative coating manufacturing enterprise, and measured with workplace test results and occupational health examination. Results: The positions of oily painters, water-borne painters, filling workers and packers who contacted noise were moderate harm. And positions of color workers who contacted chromic acid salts, oily painters who contacted butyl acetate were mild harm. Other positions were harmless. The abnormal rate of contacting noise in physical examination results was 6.25%, and the abnormality was not checked by other risk factors. Conclusion: The occupational hazard risk index model can be used in the occupational health risk assessment of decorative coating manufacturing enterprises, and noise was the key harzard among occupational harzards in this enterprise.

  8. Application of NAA and BA in chemical thinning of some commercial apple cultivars

    Directory of Open Access Journals (Sweden)

    Šebek Gordana

    2015-01-01

    Full Text Available This paper presents the fruit thinning response of some commercial apple cultivars to NAA and BA plant regulators. The experiment was designed to evaluate NAA applied separately at three concentrations - 13.2 ppm, 17.82 ppm and 26.73 ppm, and BA + NAA combinations (BA - 60 ppm, 100 ppm, 120 ppm or 140 ppm + NAA 4.29 ppm for thinning the assessed apple cultivars. All treatments with NAA and BA + NAA adequately thinned 'McIntosh' and 'Jonathan', whereas the application of NAA 17.82 ppm and 26.73 ppm and the combined treatment BA 140 ppm+ NAA 4.29 ppm were effective fruit thinners for 'Prima'. In terms of the average fruit weight, number of fruits categorized as large (> 75 mm or > 65 mm, and number of fruit per trunk cross-sectional area, the treatment BA 140 ppm + NAA 4.29 ppm was most effective on 'McIntosh' and 'Prima', whereas BA 100 ppm + NAA 4.29 ppm had the best effect on 'Jonathan'.

  9. Conceptual design of a hybrid KrF laser system for ICF commercial applications

    International Nuclear Information System (INIS)

    Harris, D.B.; Lowenthal, D.D.

    1986-01-01

    KrF lasers appear to be the most efficient lasers operating near the optimal wavelength for laser fusion. Most high-efficiency, low-cost KrF laser designs use large electron-beam-driven amplifiers and use pure angular multiplexing for the required pulse compression. A recent study carried out by Los Alamos National Lab. and Spectra Technology has defied a high-efficiency hybrid KrF laser system architecture that uses both angular multiplexing and Raman beam combination. The high overall system efficiency of this hybrid design, ∼ 12%, is achieved primarily through the use of electron-beam sustained discharge lasers (EBSDL), and by using the efficient forward rotational Raman process in hydrogen. The new system appears attractive as a commercial-applications driver because the calculated efficiency is higher than the usual large electron-beam-pumped (EBP) KrF laser/pure angular multiplexing approach. In this paper, the hybrid system architecture will be described, and the trade-offs with respect to the large EBP amplifier/angular multiplexed system will be discussed

  10. Conceptual design of a hybrid KrF laser system for ICF commercial applications

    International Nuclear Information System (INIS)

    Harris, D.B.; Lowenthal, D.D.

    1986-01-01

    KrF lasers appear to be the most efficient lasers operating near the optimal wavelength for laser fusion. Most high-efficiency, low-cost KrF laser designs use large electron-beam driven amplifiers and use pure angular multiplexing for the required pulse compression. A recent study carried out by Los Alamos and Spectra Technology has defined a high-efficiency hybrid KrF laser system architecture that uses both angular multiplexing and Raman beam combination. The high overall system efficiency of this hybrid design, approximately 12%, is achieved primarily through the use of e-beam sustained discharge lasers (EBSDL), and by using the efficient forward rotational Raman process in hydrogen. The new system appears attractive as a commercial-applications driver because the calculated efficiency is higher than the usual large e-beam pumped (EBP) KrF laser/pure angular multiplexing approach. In this paper, the hybrid system architecture is described, and the tradeoffs with respect to the large EBP amplifier/angular multiplexed system are discussed

  11. Application of AmBe source neutron irradiator for determination of inorganic elements in commercial fertilizers

    International Nuclear Information System (INIS)

    Madi Filho, Tufic; Armelim, Maria Jose Aguirre; Fulas, Paulo Marcelo Marangon; Trevizam, Anderson Ricardo; Figueira, Rubens Cesar Lopes

    2005-01-01

    The rational use of fertilizers , for the soil fertility correction, contributes to the increase of agricultural production, using the same areas previously available. The quality of products could ne improved with reduced costs. Therefore, knowledge of the chemical characteristics of the correctives used is required to streamline the application and avoid excesses or deficiencies. The studied characteristics are generally limited to the essential nutrients for the nutrition of plants and animals, e.g.: Mn, Zn, P, K, Cu and those known toxic, such as: As, Cd, Hg and Pb. Neutron activation analysis (NAA) is a highly sensitive non destructive technique, for the determination of the elemental composition in samples. It has been particularly useful in the simultaneous determination of inorganic elements in complex samples of several kinds. Several analysis methods for activation are used, such as: comparative and absolute. Commercial fertilizers were analyzed applying the absolute and comparative methods. Using the absolute method, samples were submitted to neutron flux generated by an irradiator with two Am Be sources. The obtained results were compared with those obtained by the comparative method using neutrons generated in the IEA-R1 Reactor. (author)

  12. Application of a commercial diffusion type carbon meter in a sodium circuit

    International Nuclear Information System (INIS)

    Bhat, N.P.; Borgstedt, H.U.; Peric, Z.; Witting, G.

    1980-01-01

    The exchange of carbon between structural materials and liquid sodium influences the mechanical properties of components of the cooling circuits. Therefore, the estimation of the carbon content of the alkali metal and the knowledge of its carburizing potential is of importance. Since some years the measurement of the carburizing potential of sodium is easy to perform by the application of the foil equilibration method which leads to good results in spite of the very low carbon concentrations in the liquid metal. Thin foils (0.025 to 0.125 mm) of Fe-18Cr-8Ni-C alloy (corresponding to stainless steel type AISI 304) are immersed in sodium at 550 to 700 deg. C for 200 to 400 hours. The equilibrium of the carbon distribution must be reached. Chemical analyses of the steel tabs and relation of concentration to activity of carbon lead to information on the carbon concentration in the sodium, if the saturation concentration of carbon in sodium is known. The method gives arbitrary values over a longer period of time. The time needed for equilibration and analysis causes a delay for the getting of results. Therefore, there is a need for instruments which are capable to measure carbon directly in the circuits and give continuously information on the actual carbon activities in the fluid. Until 1975 only one carbon meter was commercially available. One unit in was tested a chemical analytical sodium circuit

  13. The New Anechoic Shielded Chambers Designed for Space and Commercial Applications at LIT

    Science.gov (United States)

    da Silva, Benjamim; Galvao, M. C.; Pereira, Clovis Solano

    2008-01-01

    The main objective of this paper is to present the capabilities of the new anechoic shielded rooms designed for space and commercial applications as part of the Integration and Testing Laboratory (LIT, Laboratorio de Integracao e Testes) in Brazil. A new anechoic shielded room named CBA2 has been in full operation since March 2007 and a remodeled chamber CBA1 is planned to be ready by the end of 2008, replacing an old facility which was in operation for the last 18 years. The Brazilian Space Program started with very small and simple satellites and the old CBA1 chamber was conceived in 1987 to accomplish the EMI/EMC tests not requiring significant volumes. Since the very beginning this facility was also used by the private sector for other applications mainly due to the absorption of digital electronics in all kind of products. The intense use of this facility during the last years, operating three shifts a day, caused a normal degradation and imposed several limitations. Therefore, a new totally remodeled chamber was designed considering the state of the art in terms of absorbers and associated instrumentation. On the other hand the facility CBA2 was conceived, designed and implemented to test large satellites taking into account the advance of the technology in terms of RF frequencies, power level, testing methodologies and several other factors. A very interesting and unique aspect of this project was the partnership between the private sector and governmental institution. As a result, the total investment was shared between several companies and consequently a time-sharing use of the facility as well.

  14. 77 FR 34971 - Request for Applicants for Appointment to the Advisory Committee on Commercial Operations of...

    Science.gov (United States)

    2012-06-12

    ... automation, informed compliance and compliance assessment, account-based processing, commercial enforcement... professional biography or resume; Home address and telephone number; Work address, telephone number, and email...

  15. 40 CFR 171.7 - Submission and approval of State plans for certification of commercial and private applicators of...

    Science.gov (United States)

    2010-07-01

    ... authorities are pending enactment and/or promulgation, the Governor (or Chief Executive) may request that a...) Any changes in commercial applicator subcategories. (iii) A summary of enforcement activities related... contents of examinations (e.g., multiple choice, true-false) and submission of sample examination questions...

  16. Integrated and Intelligent Manufacturing: Perspectives and Enablers

    Directory of Open Access Journals (Sweden)

    Yubao Chen

    2017-10-01

    Full Text Available With ever-increasing market competition and advances in technology, more and more countries are prioritizing advanced manufacturing technology as their top priority for economic growth. Germany announced the Industry 4.0 strategy in 2013. The US government launched the Advanced Manufacturing Partnership (AMP in 2011 and the National Network for Manufacturing Innovation (NNMI in 2014. Most recently, the Manufacturing USA initiative was officially rolled out to further “leverage existing resources... to nurture manufacturing innovation and accelerate commercialization” by fostering close collaboration between industry, academia, and government partners. In 2015, the Chinese government officially published a 10-year plan and roadmap toward manufacturing: Made in China 2025. In all these national initiatives, the core technology development and implementation is in the area of advanced manufacturing systems. A new manufacturing paradigm is emerging, which can be characterized by two unique features: integrated manufacturing and intelligent manufacturing. This trend is in line with the progress of industrial revolutions, in which higher efficiency in production systems is being continuously pursued. To this end, 10 major technologies can be identified for the new manufacturing paradigm. This paper describes the rationales and needs for integrated and intelligent manufacturing (i2M systems. Related technologies from different fields are also described. In particular, key technological enablers, such as the Internet of Things and Services (IoTS, cyber-physical systems (CPSs, and cloud computing are discussed. Challenges are addressed with applications that are based on commercially available platforms such as General Electric (GE’s Predix and PTC’s ThingWorx.

  17. 78 FR 12102 - Manufacturer of Controlled Substances; Notice of Application; Mallinckrodt, LLC

    Science.gov (United States)

    2013-02-21

    ... plans to manufacture the listed controlled substances for internal use and for sale to other companies... Enforcement Administration, Office of Diversion Control, Federal Register Representative (ODL), 8701...: February 8, 2013. Joseph T. Rannazzisi, Deputy Assistant Administrator, Office of Diversion Control, Drug...

  18. 76 FR 43259 - Foreign-Trade Zone 109-Watertown, NY, Application for Manufacturing Authority, North American...

    Science.gov (United States)

    2011-07-20

    ... for the U.S. market and export. The manufacturing process under FTZ procedures would involve blending... finished tape's value) are woven cotton and polyester/cotton textile fabrics (duty rates: 10.5, 14.9%). The... company anticipates that some 58 percent of the plant's shipments will be exported. On its domestic sales...

  19. International manufacturing and logistics: application of a design method in five case studies

    NARCIS (Netherlands)

    Vos, G.C.J.M.

    1993-01-01

    International manufacturing and logistics has become an important topic for an increasing number of industrial firms. In this paper, a design method will be described which is aimed at supporting managers in decisions regarding the (re)design of international logistic structures. The heart of this

  20. 40 CFR 86.1851-01 - Application of good engineering judgment to manufacturers' decisions.

    Science.gov (United States)

    2010-07-01

    ... engineering judgment in making all decisions called for under this subpart, including but not limited to... overlooked, that the decision was not made in good faith, or that the decision was not made with a rational... judgment to manufacturers' decisions. 86.1851-01 Section 86.1851-01 Protection of Environment ENVIRONMENTAL...

  1. Effect of changes to the manufacturer application techniques 
on the shear bond strength of simplified dental adhesives.

    Science.gov (United States)

    Chasqueira, Ana Filipa; Arantes-Oliveira, Sofia; Portugal, Jaime

    2013-09-13

    The aim of this work was to assess the shear bond strength (SBS) between a composite resin and dentin, promoted by two dental adhesive systems (one-step self-etching adhesive Easy Bond [3M ESPE], and two-step etch-and-rinse adhesive Scotchbond 1XT [3M ESPE]) with different application protocols (per manufacturer's instruction (control group); with one to four additional adhesive layers; or with an extra hydrophobic adhesive layer). Proximal enamel was removed from ninety caries-free human molars to obtain two dentin discs per tooth, which were randomly assigned to twelve experimental groups (n=15). After adhesion protocol, the composite resin (Filtek Z250 [3M ESPE]) was applied. Specimens were mounted in the Watanabe test device and shear bond test was performed in a universal testing machine with a crosshead speed of 5 mm/min. Data were analyzed with ANOVA followed by Student-Newman-Keuls tests (PScotchbond 1XT per manufacturer's instructions (27.15±2.99 MPa). Easy Bond yielded higher SBS values than Scotchbond 1XT. There were no statistically significant differences (P>0.05) between the application protocols tested, except for the three and four layers groups, that presented higher SBS results compared to manufacturer's instruction groups (Padhesive layers when using Easy Bond and Scotchbond 1XT adhesives, since it improves SBS values without consuming much time.

  2. Application of microCT to the non-destructive testing of an additive manufactured titanium component

    Directory of Open Access Journals (Sweden)

    Anton du Plessis

    2015-11-01

    Full Text Available In this paper the application of X-ray microCT to the non-destructive testing of an additive manufactured titanium alloy component of complex geometry is demonstrated. Additive manufacturing of metal components is fast growing and shows great promise, yet these parts may contain defects which affect mechanical properties of the components. In this work a layered form of defect is found by microCT, which would have been very difficult or impossible to detect by other non-destructive testing methods due to the object complexity, defect size and shape and because the pores are entirely contained inside the object and not connected to the surface. Additionally, this test part was subjected to hot isostatic pressing (HIPPING and subsequently scanned. Comparing before and after scans by alignment of the volumes allows visualization and quantification of the pore size changes. The application of X-ray microCT to additive manufacturing is thus demonstrated in this example to be an ideal combination, especially for process improvements and for high value components.

  3. Design and dosimetry characteristics of a commercial applicator system for intra-operative electron beam therapy utilizing ELEKTA Precise accelerator.

    Science.gov (United States)

    Nevelsky, Alexander; Bernstein, Zvi; Bar-Deroma, Raquel; Kuten, Abraham; Orion, Itzhak

    2010-07-19

    The design concept and dosimetric characteristics of a new applicator system for intraoperative radiation therapy (IORT) are presented in this work. A new hard-docking commercial system includes polymethylmethacrylate (PMMA) applicators with different diameters and applicator end angles and a set of secondary lead collimators. A telescopic device allows changing of source-to-surface distance (SSD). All measurements were performed for 6, 9, 12 and 18 MeV electron energies. Output factors and percentage depth doses (PDD) were measured in a water phantom using a plane-parallel ion chamber. Isodose contours and radiation leakage were measured using a solid water phantom and radiographic films. The dependence of PDD on SSD was checked for the applicators with the smallest and the biggest diameters. SSD dependence of the output factors was measured. Hardcopies of PDD and isodose contours were prepared to help the team during the procedure on deciding applicator size and energy to be chosen. Applicator output factors are a function of energy, applicator size and applicator type. Dependence of SSD correction factors on applicator size and applicator type was found to be weak. The same SSD correction will be applied for all applicators in use for each energy. The radiation leakage through the applicators is clinically acceptable. The applicator system enables effective collimation of electron beams for IORT. The data presented are sufficient for applicator, energy and monitor unit selection for IORT treatment of a patient.

  4. Applications of commercial biosensors in clinical, food, environmental, and biothreat/biowarfare analyses.

    Science.gov (United States)

    Bahadır, Elif Burcu; Sezgintürk, Mustafa Kemal

    2015-06-01

    The lack of specific, low-cost, rapid, sensitive, and easy detection of biomolecules has resulted in the development of biosensor technology. Innovations in biosensor technology have enabled many biosensors to be commercialized and have enabled biomolecules to be detected onsite. Moreover, the emerging technologies of lab-on-a-chip microdevices and nanosensors offer opportunities for the development of new biosensors with much better performance. Biosensors were first introduced into the laboratory by Clark and Lyons. They developed the first glucose biosensor for laboratory conditions. Then in 1973, a glucose biosensor was commercialized by Yellow Springs Instruments. The commercial biosensors have small size and simple construction and they are ideal for point-of-care biosensing. In addition to glucose, a wide variety of metabolites such as lactate, cholesterol, and creatinine can be detected by using commercial biosensors. Like the glucose biosensors (tests) other commercial tests such as for pregnancy (hCG), Escherichia coli O157, influenza A and B viruses, Helicobacter pylori, human immunodeficiency virus, tuberculosis, and malaria have achieved success. Apart from their use in clinical analysis, commercial tests are also used in environmental (such as biochemical oxygen demand, nitrate, pesticide), food (such as glutamate, glutamine, sucrose, lactose, alcohol, ascorbic acid), and biothreat/biowarfare (Bacillus anthracis, Salmonella, Botulinum toxin) analysis. In this review, commercial biosensors in clinical, environmental, food, and biowarfare analysis are summarized and the commercial biosensors are compared in terms of their important characteristics. This is the first review in which all the commercially available tests are compiled together. Copyright © 2015 Elsevier Inc. All rights reserved.

  5. Technology data characterizing water heating in commercial buildings: Application to end-use forecasting

    Energy Technology Data Exchange (ETDEWEB)

    Sezgen, O.; Koomey, J.G.

    1995-12-01

    Commercial-sector conservation analyses have traditionally focused on lighting and space conditioning because of their relatively-large shares of electricity and fuel consumption in commercial buildings. In this report we focus on water heating, which is one of the neglected end uses in the commercial sector. The share of the water-heating end use in commercial-sector electricity consumption is 3%, which corresponds to 0.3 quadrillion Btu (quads) of primary energy consumption. Water heating accounts for 15% of commercial-sector fuel use, which corresponds to 1.6 quads of primary energy consumption. Although smaller in absolute size than the savings associated with lighting and space conditioning, the potential cost-effective energy savings from water heaters are large enough in percentage terms to warrant closer attention. In addition, water heating is much more important in particular building types than in the commercial sector as a whole. Fuel consumption for water heating is highest in lodging establishments, hospitals, and restaurants (0.27, 0.22, and 0.19 quads, respectively); water heating`s share of fuel consumption for these building types is 35%, 18% and 32%, respectively. At the Lawrence Berkeley National Laboratory, we have developed and refined a base-year data set characterizing water heating technologies in commercial buildings as well as a modeling framework. We present the data and modeling framework in this report. The present commercial floorstock is characterized in terms of water heating requirements and technology saturations. Cost-efficiency data for water heating technologies are also developed. These data are intended to support models used for forecasting energy use of water heating in the commercial sector.

  6. Commercial applications of solar total energy systems. Third quarterly progress report, November 1, 1976--January 31, 1977

    Energy Technology Data Exchange (ETDEWEB)

    1977-09-01

    The application of Solar Total Energy System (STES) to the commercial sector (e.g., office buildings, shopping centers, retail stores, etc.) in the United States is investigated. Candidate solar-thermal and solar-photovoltaic concepts are considered for providing on-site electrical power generation as well as thermal energy for both heating and cooling applications. The solar-thermal concepts include the use of solar concentrators (distributed or central-receiver) for collection of the thermal energy for conversion to electricity by means of a Rankine-cycle or Brayton-cycle power-conversion system. Recoverable waste heat from the power-generation process is utilized to help meet the building thermal-energy demand. Evaluation methodology is identified to allow ranking and/or selection of the most cost-effective concept for commercial-building applications.

  7. Characteristics of commercially available well scintillation counting systems

    International Nuclear Information System (INIS)

    Morris, A.C. Jr.; Dudley, R.A.

    1977-01-01

    The document contains data on commercially available well scintillation counting systems as collected during early 1977, and up-dated in July 1977, by the staff of the Medical Application Section, Division of Life Sciences, IAEA. These data also appear as Appendix 2 of IAEA-201, Well Scintillation Counting Systems for Nuclear Medicine Applications in Developing Countries, Vienna, 1977. An attempt was made to include instruments currently offered by all manufacturers. However, it is inevitable that several manufacturers remain unknown to the Section, and a number of known manufacturers failed to provide adequate information. (orig.) [de

  8. CAD/CAM/AM applications in the manufacture of dental appliances.

    Science.gov (United States)

    Al Mortadi, Noor; Eggbeer, Dominic; Lewis, Jeffrey; Williams, Robert J

    2012-11-01

    The purposes of this study were to apply the latest developments in additive manufacturing (AM) construction and to evaluate the effectiveness of these computer-aided design and computer-aided manufacturing (CAD/CAM) techniques in the production of dental appliances. In addition, a new method of incorporating wire into a single build was developed. A scanner was used to capture 3-dimensional images of Class II Division 1 dental models that were translated onto a 2-dimensional computer screen. Andresen and sleep-apnea devices were designed in 3 dimensions by using FreeForm software (version 11; Geo Magics SensAble Group, Wilmington, Mass) and a phantom arm. The design was then exported and transferred to an AM machine for building. Copyright © 2012 American Association of Orthodontists. Published by Mosby, Inc. All rights reserved.

  9. An Evidence-Based Environmental Perspective Of Manufactured Silver Nanoparticle In Syntheses And Applications: A Systematic Review And Critical Appraisal Of Peer-Reviewed Scientific Papers

    Science.gov (United States)

    Most recently, renewed interest has arisen in manufactured silver nanoparticles because of their unusually enhanced physiochemical properties and biological activities compared to the bulk parent materials. A wide range of applications has emerged in consumer products ranging fr...

  10. Application of Lean Focus onManufacturing Process : A Case Study of an American Furniture Company

    OpenAIRE

    ZHAO, QIAN; ZHOU, BOWEN

    2010-01-01

    Introduction: To improvement the target company’s manufacturing process by applyinglean principles, including using and analyzing the internal value stream mapping. Asmore and more companies have paid attention to implement lean thinking in theirmanufacturing process, the value stream mapping played an important role for manycompanies to make a transition from their traditional production systems to lean systems.The content and resources of this master thesis come from an American furnitureco...

  11. Introducing a Novel Hybrid Artificial Intelligence Algorithm to Optimize Network of Industrial Applications in Modern Manufacturing

    Directory of Open Access Journals (Sweden)

    Aydin Azizi

    2017-01-01

    Full Text Available Recent advances in modern manufacturing industries have created a great need to track and identify objects and parts by obtaining real-time information. One of the main technologies which has been utilized for this need is the Radio Frequency Identification (RFID system. As a result of adopting this technology to the manufacturing industry environment, RFID Network Planning (RNP has become a challenge. Mainly RNP deals with calculating the number and position of antennas which should be deployed in the RFID network to achieve full coverage of the tags that need to be read. The ultimate goal of this paper is to present and evaluate a way of modelling and optimizing nonlinear RNP problems utilizing artificial intelligence (AI techniques. This effort has led the author to propose a novel AI algorithm, which has been named “hybrid AI optimization technique,” to perform optimization of RNP as a hard learning problem. The proposed algorithm is composed of two different optimization algorithms: Redundant Antenna Elimination (RAE and Ring Probabilistic Logic Neural Networks (RPLNN. The proposed hybrid paradigm has been explored using a flexible manufacturing system (FMS, and results have been compared with Genetic Algorithm (GA that demonstrates the feasibility of the proposed architecture successfully.

  12. Three-Dimensional Printing of Multifunctional Nanocomposites: Manufacturing Techniques and Applications.

    Science.gov (United States)

    Farahani, Rouhollah D; Dubé, Martine; Therriault, Daniel

    2016-07-01

    The integration of nanotechnology into three-dimensional printing (3DP) offers huge potential and opportunities for the manufacturing of 3D engineered materials exhibiting optimized properties and multifunctionality. The literature relating to different 3DP techniques used to fabricate 3D structures at the macro- and microscale made of nanocomposite materials is reviewed here. The current state-of-the-art fabrication methods, their main characteristics (e.g., resolutions, advantages, limitations), the process parameters, and materials requirements are discussed. A comprehensive review is carried out on the use of metal- and carbon-based nanomaterials incorporated into polymers or hydrogels for the manufacturing of 3D structures, mostly at the microscale, using different 3D-printing techniques. Several methods, including but not limited to micro-stereolithography, extrusion-based direct-write technologies, inkjet-printing techniques, and popular powder-bed technology, are discussed. Various examples of 3D nanocomposite macro- and microstructures manufactured using different 3D-printing technologies for a wide range of domains such as microelectromechanical systems (MEMS), lab-on-a-chip, microfluidics, engineered materials and composites, microelectronics, tissue engineering, and biosystems are reviewed. Parallel advances on materials and techniques are still required in order to employ the full potential of 3D printing of multifunctional nanocomposites. © 2016 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  13. Estimating commercial property prices: an application of cokriging with housing prices as ancillary information

    Science.gov (United States)

    Montero-Lorenzo, José-María; Larraz-Iribas, Beatriz; Páez, Antonio

    2009-12-01

    A vast majority of the recent literature on spatial hedonic analysis has been concerned with residential property values, with only very few examples of studies focused on commercial property prices. The dearth of studies can be attributed to some of the challenges faced in the analysis of commercial properties, in particular the scarcity of information compared to residential transactions. In order to address this issue, in this paper we propose the use of cokriging and housing prices as ancillary information to estimate commercial property prices. Cokriging takes into account the spatial autocorrelation structure of property prices, and the use of more abundant information on housing prices helps to improve the accuracy of property value estimates. A case study of Toledo in Spain, a city for which commercial activity stemming from tourism is one of the key elements of the economy in the city, demonstrates that substantial accuracy and precision gains can be obtained from the use of cokriging.

  14. Future Role of Application of New Technologies in Small-and Medium Scale Manufacturing Systems - Regarding Intelligent and Advanced Manufacturing Systems in Northern Peripheral Area

    OpenAIRE

    Somlò, Kinga; Sziebig, Gabor

    2017-01-01

    Accepted manuscript version. Link to publishers version: http://doi.org/10.1109/ISIE.2017.8001510 Nowadays the concept of Industry 4.0. and the relating intelligent manufacturing system are getting more and more current and well-known. In the past years the outstanding development of different areas such as information technology computer science, machining, robotics and so on, made possible a comprehensive transformation of the manufacturing systems. Present paper aims to give a gener...

  15. Moving research to patient applications through commercialization: understanding and evaluating the role of intellectual property.

    Science.gov (United States)

    Patino, Robert M

    2010-03-01

    The advancement of research from discovery to the delivery of medical care can be limited without the support of industry to sponsor its continued development. Federal government financial support is generally crucial in early-stage development through funding from the NIH, National Science Foundation, and other federal agencies; however, government support generally stops shortly after basic research discoveries have been reported. Much of the cessation of financial support derives from the government's regulatory responsibilities, as sponsoring the commercialization of a product conflicts with regulation of the approval for clinical use of a drug or device. Furthermore, differences in goals, resources, and flexibility render government, as compared with private industry, inefficient and less responsive to market demands with regard to stream-lining the development of and enhancing the quality of products and services offered. Thus, industry and private investment provide the bridge that converts new discoveries into healthcare products that are available to consumers and patients. This conversion occurs through commercialization, which involves both high risks and high rewards. Taking advantage of the commercialization option for research development requires an understanding of the technology transfer process. This article reviews 5 topics: 1) industry motivation to invest in academic research; 2) institutional considerations in partnering with industry; 3) academia's interactions with inventors in the commercialization process; 4) the research institution's route to commercialization, and 5) the role of intellectual property and commercialization in the advancement of healthcare.

  16. Verification of fluid-structure-interaction algorithms through the method of manufactured solutions for actuator-line applications

    Science.gov (United States)

    Vijayakumar, Ganesh; Sprague, Michael

    2017-11-01

    Demonstrating expected convergence rates with spatial- and temporal-grid refinement is the ``gold standard'' of code and algorithm verification. However, the lack of analytical solutions and generating manufactured solutions presents challenges for verifying codes for complex systems. The application of the method of manufactured solutions (MMS) for verification for coupled multi-physics phenomena like fluid-structure interaction (FSI) has only seen recent investigation. While many FSI algorithms for aeroelastic phenomena have focused on boundary-resolved CFD simulations, the actuator-line representation of the structure is widely used for FSI simulations in wind-energy research. In this work, we demonstrate the verification of an FSI algorithm using MMS for actuator-line CFD simulations with a simplified structural model. We use a manufactured solution for the fluid velocity field and the displacement of the SMD system. We demonstrate the convergence of both the fluid and structural solver to second-order accuracy with grid and time-step refinement. This work was funded by the U.S. Department of Energy, Office of Energy Efficiency and Renewable Energy, Wind Energy Technologies Office, under Contract No. DE-AC36-08-GO28308 with the National Renewable Energy Laboratory.

  17. Summary of the Manufacture, Testing and Model Validation of a Full-Scale Radiator for Fission Surface Power Applications

    Science.gov (United States)

    Ellis, David L.; Calder, James; Siamidis, John

    2011-01-01

    A full-scale radiator for a lunar fission surface power application was manufactured by Material innovations, Inc., for the NASA Glenn Research Center. The radiator was designed to reject 6 kWt with an inlet water temperature of 400 K and a water mass flow rate of 0.5 kg/s. While not flight hardware, the radiator incorporated many potential design features and manufacturing techniques for future flight hardware. The radiator was tested at NASA Glenn Research Center for heat rejection performance. The results showed that the radiator design was capable of rejecting over 6 kWt when operating at the design conditions. The actual performance of the radiator as a function of operational manifolds, inlet water temperature and facility sink temperature was compared to the predictive model developed by NASA Glenn Research Center. The results showed excellent agreement with the model with the actual average face sheet temperature being within 1% of the predicted value. The results will be used in the design and production of NASA s next generation fission power heat rejection systems. The NASA Glenn Research Center s Technology Demonstration Unit will be the first project to take advantage of the newly developed manufacturing techniques and analytical models.

  18. Method for the manufacture of a superconductive Nb3Sn layer on a niobium surface for high frequency applications

    International Nuclear Information System (INIS)

    Martens, H.

    1978-01-01

    A manufacturing method for depositing an Nb 3 Sn layer on a niobium surface for high frequency applications comprising developing a tin vapor atmosphere which also contains a highly volatile tin compound in the gaseous state, and holding the portions of the surface which are to be provided with the Nb 3 Sn layer at a temperature of between 900 0 and 1500 0 C for a predetermined period of time to form the Nb 3 Sn layer permitting niobium surfaces of any shape to be provided with Nb 3 Sn layers of high uniformity and quality

  19. 3D Systems' Technology Overview and New Applications in Manufacturing, Engineering, Science, and Education

    Science.gov (United States)

    Andrews, Mike; Weislogel, Mark; Moeck, Peter; Stone-Sundberg, Jennifer; Birkes, Derek; Hoffert, Madeline Paige; Lindeman, Adam; Morrill, Jeff; Fercak, Ondrej; Friedman, Sasha; Gunderson, Jeff; Ha, Anh; McCollister, Jack; Chen, Yongkang; Geile, John; Wollman, Andrew; Attari, Babak; Botnen, Nathan; Vuppuluri, Vasant; Shim, Jennifer; Kaminsky, Werner; Adams, Dustin; Graft, John

    2014-01-01

    Abstract Since the inception of 3D printing, an evolutionary process has taken place in which specific user and customer needs have crossed paths with the capabilities of a growing number of machines to create value-added businesses. Even today, over 30 years later, the growth of 3D printing and its utilization for the good of society is often limited by the various users' understanding of the technology for their specific needs. This article presents an overview of current 3D printing technologies and shows numerous examples from a multitude of fields from manufacturing to education. PMID:28473997

  20. The Financial Factors that Determine the Profitability: An Application on Manufacturing Firms Traded in BIST

    Directory of Open Access Journals (Sweden)

    Mesut DOĞAN

    2016-01-01

    Full Text Available This paper examines the determinants of financial profitability firms listed in Borsa Istanbul (BIST. The study made use of data of 136 firms continuously active in BIST manufacturing industry between 2005 and 2012. In the study, panel data analysis was used. According to the findings it is determined that Return on Equity and Return on Assets have a positive relationship with the total assets, however, leverage ratio have a negative relationship. In addition, a statistically insignificant relation was established between firm age, liquid ratio and profitability. Findings of the research are important for investors, researchers, executives of business.

  1. Application of laser additive manufacturing to produce dies for aluminium high pressure die casting

    CSIR Research Space (South Africa)

    Pereira, MFVT

    2012-07-01

    Full Text Available through immersion in liquid aluminium. The dipping cycle closely resembles the heating and cooling cycle of a typical aluminium die under casting conditions. The suitability of any LAM technology, that can produce fully dense metallic components... cost vs wrought manufactured 5.2 1,7 2. 2 Average cost Very High Medium High Table 3: Processing and finishing costs of test coupons 3.1 Cyclic Immersion in Molten Aluminium Figure 3 below shows the testing apparatus developed to simulate...

  2. Application of commercial RIA kit in investigating milk contamination with M1 aflatoxin

    International Nuclear Information System (INIS)

    Fukal, L.

    1988-01-01

    Measured were samples of commercially sold milk produced by two Czech dairies and samples of unprocessed cow's milk from three farms. The determination of aflatoxin M 1 in liquid milk was carried out with a RIA-test-aflatoxin M 1 B 1 kit. The range of the calibration curve of the kit is 0.06 to 2.0 μg/l. In samples of commercially sold milk a higher share of aflatoxin M 1 free samples was found (93%) and 7% samples contained 0.050 to 0.1 μg aflatoxin/l. The dilution effect was manifest in commercially sold milk. On the other hand in 7% samples of raw milk aflatoxin concentration exceeded the limits set by hygiene inspection bodies for consumption by infants. The detected aflatoxin concentrations are compared with data from abroad. (E.S.). 2 tabs., 13 refs

  3. Practical application of game theory based production flow planning method in virtual manufacturing networks

    Science.gov (United States)

    Olender, M.; Krenczyk, D.

    2016-08-01

    Modern enterprises have to react quickly to dynamic changes in the market, due to changing customer requirements and expectations. One of the key area of production management, that must continuously evolve by searching for new methods and tools for increasing the efficiency of manufacturing systems is the area of production flow planning and control. These aspects are closely connected with the ability to implement the concept of Virtual Enterprises (VE) and Virtual Manufacturing Network (VMN) in which integrated infrastructure of flexible resources are created. In the proposed approach, the players role perform the objects associated with the objective functions, allowing to solve the multiobjective production flow planning problems based on the game theory, which is based on the theory of the strategic situation. For defined production system and production order models ways of solving the problem of production route planning in VMN on computational examples for different variants of production flow is presented. Possible decision strategy to use together with an analysis of calculation results is shown.

  4. Process-Structure Linkages Using a Data Science Approach: Application to Simulated Additive Manufacturing Data

    International Nuclear Information System (INIS)

    Popova, Evdokia; Rodgers, Theron M.; Gong, Xinyi; Cecen, Ahmet; Madison, Jonathan D.; Kalidindi, Surya R.

    2017-01-01

    A novel data science workflow is developed and demonstrated to extract process-structure linkages (i.e., reduced-order model) for microstructure evolution problems when the final microstructure depends on (simulation or experimental) processing parameters. Our workflow consists of four main steps: data pre-processing, microstructure quantification, dimensionality reduction, and extraction/validation of process-structure linkages. These methods that can be employed within each step vary based on the type and amount of available data. In this paper, this data-driven workflow is applied to a set of synthetic additive manufacturing microstructures obtained using the Potts-kinetic Monte Carlo (kMC) approach. Additive manufacturing techniques inherently produce complex microstructures that can vary significantly with processing conditions. Using the developed workflow, a low-dimensional data-driven model was established to correlate process parameters with the predicted final microstructure. In addition, the modular workflows developed and presented in this work facilitate easy dissemination and curation by the broader community.

  5. Challenges faced in selection, manufacture, quality assurance and qualification of the components for FBTR CRDM applications

    International Nuclear Information System (INIS)

    Ramesh, E.; Krovvidi, S.C.S.P. Kumar; Sarangarajan, S.; Kasinathan, N.; Srinivasan, G.

    2015-01-01

    Fast Breeder Test Reactor (FBTR) is a sodium cooled type experimental reactor. Six numbers of Control Rod Drive Mechanisms (CRDM) along with their B4C control rods perform reactor start up, controlled shutdown, reactivity control for power changing and burn-up compensation and to shut down the reactor by SCRAM action during abnormal conditions. Lower part of the CRDM which consists of translation tube, outer sheath and gripper is partially immersed in sodium. Nested Ripple type Welded Disc Bellows (NRWDB) called translation bellows prevents entry of sodium in the space between the translation tube and outer sheath and acts as primary leak tight barrier. Silicone bellows which is near ground level elevation acts as secondary leak tight barrier. Non standard Aluminium bronze rod was used as raw material for various drive components in CRDM. These components were imported earlier from FRANCE. Indigenous development of these items and bellows was taken up due to difficulties in procurement. Extensive studies were carried out on selection of materials, establishment of manufacturing procedures and stringent Quality Assurance Program (QAP) to ensure defect free component during indigenous development. Suitable methodology was arrived for qualification of these components. Successful development of silicone bellows and Aluminium bronze rods were completed as per our requirements and selection, establishment of manufacturing procedure and QAP were completed for (NRWDB). Prototype development of NRWDB is in progress. (author)

  6. Application of rapid prototyping technology in the prototype manufacturing for evaluation of NPP components and equipments

    International Nuclear Information System (INIS)

    Park, C. Y.; Kim, J. W.; Shon, H. K.; Choi, H. S.; Yang, D. Y.

    2001-01-01

    A brief overview of rapid prototyping technology in which a part with complex shape can be produced easily and rapidly in a layer-by-layer additive manner is given in this article. In addition, a prototype model of a complex fan is manufactured using three-dimensional solid CAD modeling and Laminated Object Manufacturing (LOM), a rapid prototyping technology. This enables designers to verify and modify design rapidly at an early stage of product development; and the prototype model of a fan can be used as a pattern for various secondary casting process such as vacumm casting, lost-paper casting to make prototypes of a fan. It has been shown that the combination of three-dimensional solid CAD modeling and rapid prototyping technology can reduce greatly the cost and time of prototyping of fans and turbine blades in comparison with conventional CNC machining. It should also be noted that rapid prototyping technology enables the visualization of various physical and chemical defects at a nuclear power plant so that it can help engineers understand those defects in an effective way

  7. Good Manufacturing Practices (GMP) / Good Laboratory Practices (GLP) Review and Applicability for Chemical Security Enhancements

    Energy Technology Data Exchange (ETDEWEB)

    Iveson, Steven W. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States). International Chemical Security Threat Reduction

    2014-11-01

    Global chemical security has been enhanced through the determined use and integration of both voluntary and legislated standards. Many popular standards contain components that specifically detail requirements for the security of materials, facilities and other vital assets. In this document we examine the roll of quality management standards and how they affect the security culture within the institutions that adopt these standards in order to conduct business within the international market place. Good manufacturing practices and good laboratory practices are two of a number of quality management systems that have been adopted as law in many nations. These standards are designed to protect the quality of drugs, medicines, foods and analytical test results in order to provide the world-wide consumer with safe and affective products for consumption. These standards provide no established security protocols and yet manage to increase the security of chemicals, materials, facilities and the supply chain via the effective and complete control over the manufacturing, the global supply chains and testing processes. We discuss the means through which these systems enhance security and how nations can further improve these systems with additional regulations that deal specifically with security in the realm of these management systems. We conclude with a discussion of new technologies that may cause disruption within the industries covered by these standards and how these issues might be addressed in order to maintain or increase the level of security within the industries and nations that have adopted these standards.

  8. Performance evaluation of a commercially available heat flow calorimeter and applicability assessment for safeguarding special nuclear materials

    International Nuclear Information System (INIS)

    Bracken, D.S.; Biddle, R.; Rudy, C.

    1998-01-01

    The performance characteristics of a commercially available heat-flow calorimeter will be presented. The heat-flow sensors within the calorimeter are based on thermopile technology with a vendor-quoted sensitivity of 150 microV/mW. The calorimeter is a full-twin design to compensate for ambient temperature fluctuations. The efficacy of temperature fluctuation compensations will also be detailed. Finally, an assessment of design applicability to special nuclear materials control and accountability and safeguarding will be presented

  9. Development and Hot-fire Testing of Additively Manufactured Copper Combustion Chambers for Liquid Rocket Engine Applications

    Science.gov (United States)

    Gradl, Paul R.; Greene, Sandy Elam; Protz, Christopher S.; Ellis, David L.; Lerch, Bradley A.; Locci, Ivan E.

    2017-01-01

    NASA and industry partners are working towards fabrication process development to reduce costs and schedules associated with manufacturing liquid rocket engine components with the goal of reducing overall mission costs. One such technique being evaluated is powder-bed fusion or selective laser melting (SLM), commonly referred to as additive manufacturing (AM). The NASA Low Cost Upper Stage Propulsion (LCUSP) program was designed to develop processes and material characterization for GRCop-84 (a NASA Glenn Research Center-developed copper, chrome, niobium alloy) commensurate with powder-bed AM, evaluate bimetallic deposition, and complete testing of a full scale combustion chamber. As part of this development, the process has been transferred to industry partners to enable a long-term supply chain of monolithic copper combustion chambers. To advance the processes further and allow for optimization with multiple materials, NASA is also investigating the feasibility of bimetallic AM chambers. In addition to the LCUSP program, NASA has completed a series of development programs and hot-fire tests to demonstrate SLM GRCop-84 and other AM techniques. NASA's efforts include a 4K lbf thrust liquid oxygen/methane (LOX/CH4) combustion chamber and subscale thrust chambers for 1.2K lbf LOX/hydrogen (H2) applications that have been designed and fabricated with SLM GRCop-84. The same technologies for these lower thrust applications are being applied to 25-35K lbf main combustion chamber (MCC) designs. This paper describes the design, development, manufacturing and testing of these numerous combustion chambers, and the associated lessons learned throughout their design and development processes.

  10. Synthesis and characterization of Ti-27.5Nb alloy made by CLAD® additive manufacturing process for biomedical applications

    International Nuclear Information System (INIS)

    Fischer, M.; Laheurte, P.; Acquier, P.; Joguet, D.; Peltier, L.; Petithory, T.; Anselme, K.; Mille, P.

    2017-01-01

    Biocompatible beta-titanium alloys such as Ti-27.5(at.%)Nb are good candidates for implantology and arthroplasty applications as their particular mechanical properties, including low Young's modulus, could significantly reduce the stress-shielding phenomenon usually occurring after surgery. The CLAD® process is a powder blown additive manufacturing process that allows the manufacture of patient specific (i.e. custom) implants. Thus, the use of Ti-27.5(at.%)Nb alloy formed by CLAD® process for biomedical applications as a mean to increase cytocompatibility and mechanical biocompatibility was investigated in this study. The microstructural properties of the CLAD-deposited alloy were studied with optical microscopy and electron back-scattered diffraction (EBSD) analysis. The conservation of the mechanical properties of the Ti-27.5Nb material after the transformation steps (ingot-powder atomisation-CLAD) were verified with tensile tests and appear to remain close to those of reference material. Cytocompatibility of the material and subsequent cell viability tests showed that no cytotoxic elements are released in the medium and that viable cells proliferated well. - Highlights: • Biomimetic implants can be provided from additive manufacturing with beta-titanium alloys. • We studied the properties of a Ti-Nb alloy elaborated with a laser deposition process. • TiNb alloy processed by LMD consists of only beta phase due to rapid cooling. • No preferential crystallographic texture is observed with EBSD analyses. • TiNb samples showed a combination of high strength and low Young's modulus.

  11. Synthesis and characterization of Ti-27.5Nb alloy made by CLAD® additive manufacturing process for biomedical applications

    Energy Technology Data Exchange (ETDEWEB)

    Fischer, M. [LEM3, Université de Lorraine, Ile du Saulcy, 57045 Metz (France); Laheurte, P., E-mail: pascal.laheurte@univ-lorraine.fr [LEM3, Université de Lorraine, Ile du Saulcy, 57045 Metz (France); Acquier, P. [IREPA Laser, Institut Carnot Mica, Parc d' Innovation, 67400 Illkirch (France); Joguet, D. [LERMPS, Université de Technologie de Belfort Montbéliard, Sevenans, 90010 Belfort (France); Peltier, L. [LEM3, Ecole Nationale Supérieure d' Arts et Métiers, 57078 Metz (France); Petithory, T.; Anselme, K. [IS2M, CNRS UMR7361, Université de Haute-Alsace, 68057 Mulhouse (France); Mille, P. [LGECO Institut National des Sciences Appliquées, 67000 Strasbourg (France)

    2017-06-01

    Biocompatible beta-titanium alloys such as Ti-27.5(at.%)Nb are good candidates for implantology and arthroplasty applications as their particular mechanical properties, including low Young's modulus, could significantly reduce the stress-shielding phenomenon usually occurring after surgery. The CLAD® process is a powder blown additive manufacturing process that allows the manufacture of patient specific (i.e. custom) implants. Thus, the use of Ti-27.5(at.%)Nb alloy formed by CLAD® process for biomedical applications as a mean to increase cytocompatibility and mechanical biocompatibility was investigated in this study. The microstructural properties of the CLAD-deposited alloy were studied with optical microscopy and electron back-scattered diffraction (EBSD) analysis. The conservation of the mechanical properties of the Ti-27.5Nb material after the transformation steps (ingot-powder atomisation-CLAD) were verified with tensile tests and appear to remain close to those of reference material. Cytocompatibility of the material and subsequent cell viability tests showed that no cytotoxic elements are released in the medium and that viable cells proliferated well. - Highlights: • Biomimetic implants can be provided from additive manufacturing with beta-titanium alloys. • We studied the properties of a Ti-Nb alloy elaborated with a laser deposition process. • TiNb alloy processed by LMD consists of only beta phase due to rapid cooling. • No preferential crystallographic texture is observed with EBSD analyses. • TiNb samples showed a combination of high strength and low Young's modulus.

  12. Synthesis and characterization of Ti-27.5Nb alloy made by CLAD® additive manufacturing process for biomedical applications.

    Science.gov (United States)

    Fischer, M; Laheurte, P; Acquier, P; Joguet, D; Peltier, L; Petithory, T; Anselme, K; Mille, P

    2017-06-01

    Biocompatible beta-titanium alloys such as Ti-27.5(at.%)Nb are good candidates for implantology and arthroplasty applications as their particular mechanical properties, including low Young's modulus, could significantly reduce the stress-shielding phenomenon usually occurring after surgery. The CLAD® process is a powder blown additive manufacturing process that allows the manufacture of patient specific (i.e. custom) implants. Thus, the use of Ti-27.5(at.%)Nb alloy formed by CLAD® process for biomedical applications as a mean to increase cytocompatibility and mechanical biocompatibility was investigated in this study. The microstructural properties of the CLAD-deposited alloy were studied with optical microscopy and electron back-scattered diffraction (EBSD) analysis. The conservation of the mechanical properties of the Ti-27.5Nb material after the transformation steps (ingot-powder atomisation-CLAD) were verified with tensile tests and appear to remain close to those of reference material. Cytocompatibility of the material and subsequent cell viability tests showed that no cytotoxic elements are released in the medium and that viable cells proliferated well. Copyright © 2017 Elsevier B.V. All rights reserved.

  13. Concept-Development of a Structure Supported Membrane for Deployable Space Applications - From Nature to Manufacture and Testing

    Science.gov (United States)

    Zander, Martin; Belvin, W. K.

    2012-01-01

    Current space applications of membrane structures include large area solar power arrays, solar sails, antennas, and numerous other large aperture devices like the solar shades of the new James Webb Space Telescope. These expandable structural systems, deployed in-orbit to achieve the desired geometry, are used to collect, reflect and/or transmit electromagnetic radiation. This work, a feasibility study supporting a diploma thesis, describes the systematic process for developing a biologically inspired concept for a structure supported (integrated) membrane, that features a rip stop principle, makes self-deployment possible and is part of an ultra-light weight space application. Novel manufacturing of membrane prototypes and test results are presented for the rip-stop concepts. Test data showed that the new membrane concept has a higher tear resistance than neat film of equivalent mass.

  14. Accelerating the commercialization of university technologies for military healthcare applications: the role of the proof of concept process

    Science.gov (United States)

    Ochoa, Rosibel; DeLong, Hal; Kenyon, Jessica; Wilson, Eli

    2011-06-01

    The von Liebig Center for Entrepreneurism and Technology Advancement at UC San Diego (vonliebig.ucsd.edu) is focused on accelerating technology transfer and commercialization through programs and education on entrepreneurism. Technology Acceleration Projects (TAPs) that offer pre-venture grants and extensive mentoring on technology commercialization are a key component of its model which has been developed over the past ten years with the support of a grant from the von Liebig Foundation. In 2010, the von Liebig Entrepreneurism Center partnered with the U.S. Army Telemedicine and Advanced Technology Research Center (TATRC), to develop a regional model of Technology Acceleration Program initially focused on military research to be deployed across the nation to increase awareness of military medical needs and to accelerate the commercialization of novel technologies to treat the patient. Participants to these challenges are multi-disciplinary teams of graduate students and faculty in engineering, medicine and business representing universities and research institutes in a region, selected via a competitive process, who receive commercialization assistance and funding grants to support translation of their research discoveries into products or services. To validate this model, a pilot program focused on commercialization of wireless healthcare technologies targeting campuses in Southern California has been conducted with the additional support of Qualcomm, Inc. Three projects representing three different universities in Southern California were selected out of forty five applications from ten different universities and research institutes. Over the next twelve months, these teams will conduct proof of concept studies, technology development and preliminary market research to determine the commercial feasibility of their technologies. This first regional program will help build the needed tools and processes to adapt and replicate this model across other regions in the

  15. Technology data characterizing refrigeration in commercial buildings: Application to end-use forecasting with COMMEND 4.0

    Energy Technology Data Exchange (ETDEWEB)

    Sezgen, O.; Koomey, J.G.

    1995-12-01

    In the United States, energy consumption is increasing most rapidly in the commercial sector. Consequently, the commercial sector is becoming an increasingly important target for state and federal energy policies and also for utility-sponsored demand side management (DSM) programs. The rapid growth in commercial-sector energy consumption also makes it important for analysts working on energy policy and DSM issues to have access to energy end-use forecasting models that include more detailed representations of energy-using technologies in the commercial sector. These new forecasting models disaggregate energy consumption not only by fuel type, end use, and building type, but also by specific technology. The disaggregation of the refrigeration end use in terms of specific technologies, however, is complicated by several factors. First, the number of configurations of refrigeration cases and systems is quite large. Also, energy use is a complex function of the refrigeration-case properties and the refrigeration-system properties. The Electric Power Research Institute`s (EPRI`s) Commercial End-Use Planning System (COMMEND 4.0) and the associated data development presented in this report attempt to address the above complications and create a consistent forecasting framework. Expanding end-use forecasting models so that they address individual technology options requires characterization of the present floorstock in terms of service requirements, energy technologies used, and cost-efficiency attributes of the energy technologies that consumers may choose for new buildings and retrofits. This report describes the process by which we collected refrigeration technology data. The data were generated for COMMEND 4.0 but are also generally applicable to other end-use forecasting frameworks for the commercial sector.

  16. 14 CFR 119.36 - Additional certificate application requirements for commercial operators.

    Science.gov (United States)

    2010-01-01

    ... following: (1) For corporate applicants: (i) The name and address of each stockholder who owns 5 percent or... person under direct or indirect control with the applicant. (2) For non-corporate applicants: (i) The... accounting principles applied on a consistent basis, and must contain the name and address of the applicant's...

  17. Application of reactors for testing neutron-induced upsets in commercial SRAMs

    International Nuclear Information System (INIS)

    Griffin, P.J.; Luera, T.F.; Sexton, F.W.; Cooper, P.J.; Karr, S.G.; Hash, G.L.; Fuller, E.

    1997-01-01

    Reactor neutron environments can be used to test/screen the sensitivity of unhardened commercial SRAMs to low-LET neutron-induced upset. Tests indicate both thermal/epithermal (< 1 keV) and fast neutrons can cause upsets in unhardened parts. Measured upset rates in reactor environments can be used to model the upset rate for arbitrary neutron spectra

  18. Energy analysis of fuel cell system for commercial greenhouse application – A feasibility study

    International Nuclear Information System (INIS)

    Vadiee, Amir; Yaghoubi, Mahmoud; Sardella, Marco; Farjam, Pardis

    2015-01-01

    Highlights: • Feasibility study of integrating a PEMFC with a commercial greenhouse. • An energy analysis has been performed in order to evaluate the energetic performance of the system. • A sensitivity analysis on the main influencing operating parameters for optimization. - Abstract: The purpose of this paper is to investigate the feasibility of integrating a proton exchange membrane fuel cell (PEMFC) system with a commercial greenhouse and assess the mutual benefits of such integration. The main objective is to recover the low quality waste heat of the PEMFC system in order to meet the thermal energy demand of a commercial greenhouse. In addition the PEMFC covers the some part of the greenhouse electrical demand. In this study an energy analysis has been performed in order to evaluate the energetic performance of the system. To achieve these aims, first, a system model has been developed using TRNSYS. Afterwards, a sensitivity analysis has been carried out varying the main influencing operating parameters in order to evaluate an optimal configuration of the system. In particular the influences of temperature and air stoichiometry have been investigated. The results show that a 3 kW fuel cell system is capable to cover approximately the 25% and 10% of the usual electricity and heat demands of a 1000 m 2 commercial greenhouse during a year, respectively

  19. Red alder kitchen cabinets—How does application of commercial stains influence customer choice?

    Science.gov (United States)

    David Nicholls; Joseph. Roos

    2007-01-01

    A better understanding of consumer reaction and preferences for red alder (Alnus rubra Bong.) secondary products will help Alaska producers in entering new markets. In this study, red alder kitchen cabinets were commercially stained to six different levels and displayed at home shows in Portland, Oregon, and Anchorage, Alaska. The stains simulated...

  20. 75 FR 33661 - Commercial Driver's License (CDL) Standards; Rotel North American Tours, LLC; Application for...

    Science.gov (United States)

    2010-06-14

    ... named drivers, employed by Rotel and possessing German CDLs, to operate commercial motor vehicles (CMVs.... ADDRESSES: You may submit comments identified by Federal Docket Management System Number FMCSA-2008-0078 by... . Follow the online instructions for submitting comments. Fax: 1-202-493-2251. Mail: Docket Management...