Działalność akademicka Henryka Batowskiego we Lwowie (1925-1927

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Sebastian Grudzień

2009-06-01

Full Text Available Henryk Batowski’s academic activity in Lvov (1925-1927The article is a contribution to the biography of an eminent Polish historian and Slavist Henryk Batowski (1907-1999. It presents his academic activity from sum- mer of 1925 until autumn of 1927. Atthattime he was studying philology atthe John Casimir University in Lvov. Batowski became a leader of several Polish student associations. Ali of them were under the influence of the National Democratic Youth. He took part in works of few other, non-academic societies, most of which were connected to Slav cooperation, the idea to which Batowski paid great attention. Neither Józef Piłsudski’s ruling camp nor an anti-government student community of Lvov were supporting Batowski’s favorite ideas.

PREFACE: Joint European Magnetic Symposia - JEMS 2010

Science.gov (United States)

Spałek, Jozef

2011-07-01

Conference banner The Joint European Magnetic Symposia JEMS 2010 took place in the complex Auditorium Maximum of the Jagiellonian University in Kraków, Poland, between 23-28 August 2010. It followed the series of the conferences in Grenoble (2001), Dresden (2004), San Sebastian (2006), and Dublin (2008). The next Symposia will be held in 2012 in Parma (Italy). The Symposia cover a broad range of aspects of magnetism and magnetic materials, as well as providing a forum for the magnetism community to discuss new concepts, properties, and developments in all branches of fundamental and applied magnetism. The JEMS 2010 Symposia were organized by the Institute of Physics of Jagiellonian University, in cooperation with AGH University of Science and Technology (Kraków), Cracow University of Technology, Institute of Nuclear Physics of the Polish Academy of Sciences in Kraków, and the Silesian University in Katowice. I thank the Local Committee, and in particular Professor Krzysztof Tomala, for their hard work long before, during, and after the Conference. We dedicate this volume to Professor Henryk Szymczak from the Institute of Physics of the Polish Academy of Sciences for his long lasting service to the magnetism community and the organizational effort in bringing this Conference to our community. Thank you Henryk! The Conference contained Plenary Sessions and 16 Symposia, which are listed below. Most of them had two chairpersons (also listed), one from abroad and one from Poland. I believe that a collective chairmanship of the Symposia is very helpful in both their organization, as well as in the reviewing process of the papers submitted to the Conference Proceedings. I would like to cordially thank all the persons listed below, who have contributed enormously to the success of our meeting. The Proceedings comprises 116 invited and contributed papers. I thank the Co-editors for their continuing work long after the Conference. Arrivederci in Parma! Jozef Spa

BBC võttis Eestis üles materjali Arvo Pärdi dokfilmi jaoks / Andres Laasik

Index Scriptorium Estoniae

Laasik, Andres, 1960-2016

2009-01-01

BBC klassikalise muusika osakond teeb filmi klassikaliste heliloojate sarja jaoks. A. Pärdi kõrval käsitletakse filmis ka poola heliloojat Henryk Goreckit. Filmi režissöör on Simon Broughton ja moderaator tuntud näitleja Simon Russell-Beale

Europa : Landschaft mit Stadt / Henryk Samsonowicz

Index Scriptorium Estoniae

Samsonowicz, Henryk

2005-01-01

Alates 8. sajandist hakkasid kirjutajad huvi tundma võõraste (väljaspool Roomat asuvate) maade vastu. Euroopa kaardile jõudsid linnad alles teise aastatuhande esimese kahe sajandi jooksul. Ida-Euroopa linnad lülitati geograafilisse kaanonisse 13.-14. sajandil

27 November 2014 - Warsaw University of Technology (PL) Vice-Rector for Research R. Bacewicz visitng the ALICE control room and undergorund experimental area with WUT students, accompanied by A. Charkiewicz and A. Siemko; joint signature ceremony with HNINP Director-General M. Jezabek

CERN Multimedia

Guillaume, Jeanneret

2014-01-01

CERN-PHOTO-201411-245-95: from left to right: Professor D.Sc.Ph.D. Rajmund Bacewicz, Vice-Rector for Research, Warsaw University of Technology, CERN Director-General R. Heuer and Prof. Marek Jeżabek, Director-General, Henryk Niewodniczanski Institute of Nuclear Physics, Republic of Poland

Correction to: Impact of a mixed educational and semi-restrictive antimicrobial stewardship project in a large teaching hospital in Northern Italy.

Science.gov (United States)

Giacobbe, Daniele Roberto; Del Bono, Valerio; Mikulska, Malgorzata; Gustinetti, Giulia; Marchese, Anna; Mina, Federica; Signori, Alessio; Orsi, Andrea; Rudello, Fulvio; Alicino, Cristiano; Bonalumi, Beatrice; Morando, Alessandra; Icardi, Giancarlo; Beltramini, Sabrina; Viscoli, Claudio

2017-12-01

A technical error led to incorrect rendering of the author group in this article. The correct authorship is as follows: Daniele Roberto Giacobbe 1 , Valerio Del Bono 1 , Malgorzata Mikulska 1 , Giulia Gustinetti 1 , Anna Marchese 2 , Federica Mina 3 , Alessio Signori 4 , Andrea Orsi 5 , Fulvio Rudello 6 , Cristiano Alicino 5 , Beatrice Bonalumi 3 , Alessandra Morando 7 , Giancarlo Icardi 5 , Sabrina Beltramini 3 , Claudio Viscoli 1 ; On behalf of the San Martino Antimicrobial Stewardship Group.

Very forward calorimeters readout and machine interface

Indian Academy of Sciences (India)

The paper describes the requirements for the readout electronics and DAQ for the instrumentation of the forward region of the future detector at the international linear collider. The preliminary design is discussed. Author Affiliations. Wojciech Wierba1 on behalf of the FCAL Collaboration. The Henryk Niewodniczański ...

Response to “Oral health in the elderly patient and its impact on general well-being: a nonsystematic review” paper

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Muc-Wierzgoń M

2015-05-01

Full Text Available Malgorzata Muc-Wierzgoń, Teresa Kokot, Ewa Nowakowska-Zajdel, Adam Błażelonis, Edyta Fatyga Department of Internal Medicine, Silesian Medical University, Bytom, PolandDear editorGil-Montoya et al has recently published an interesting article in Clinical Interventions in Aging entitled: “Oral health in the elderly patient and its impact on general well-being: a nonsystematic review”.1 Authors presented a non-systematic review of the published data regarding the oral health status of the elderly and its main repercussions, including its impact on general health and nutrition.View original paper by Gil-Montoya and colleagues.

Bagatellid : maailm / Nele-Eva Steinfeld, Ivo Heinloo

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Steinfeld, Nele-Eva

2010-01-01

Lühisõnumaid maailmast: Vene pianist Julianna Avdejeva saavutas XVI rahvusvahelisel Chopini konkursil Varssavis võidu. Suri poola helilooja Henryk Mikolaj Gorecki. Daniel Barenboimi 60 lava-aastat. Suri dirigent ja vioolamängija Rudolf Baršai. Kitarrilegend Sonny Sharrock sai oma kodulinnas enda nimelise tänava. 23. Thelonious Monki nimelise jazzkonkursi võitis Cecile McLorin Salvant. Youn Sun Nah Prantsuse müügiedetabeli tipus. Ansamblil Jamiroquai ilmus uus plaat. Suri saksofonist Marion Brown

Annual report 1991

Energy Technology Data Exchange (ETDEWEB)

Broda, R; Lesniak, L; Malecki, P; Stachura, Z; Wojciechowski, H [eds.

1993-12-31

The material presented describing the scientific activities of the Henryk Niewodniczanski Institute of Nuclear Physics in 1991 is the first annual report in several years.The arrangement of the report from various departments reflect the present structure of the Institute and is meant to help in the future task of reconstructing the Institute. Few guidelines proposed by the editorial board gave the individual departments much freedom in selecting the material and choosing the volume and format of presentation. (author).

Annual report 1991

Energy Technology Data Exchange (ETDEWEB)

Broda, R.; Lesniak, L.; Malecki, P.; Stachura, Z.; Wojciechowski, H. [eds.

1992-12-31

The material presented describing the scientific activities of the Henryk Niewodniczanski Institute of Nuclear Physics in 1991 is the first annual report in several years.The arrangement of the report from various departments reflect the present structure of the Institute and is meant to help in the future task of reconstructing the Institute. Few guidelines proposed by the editorial board gave the individual departments much freedom in selecting the material and choosing the volume and format of presentation. (author).

Annual report 1991

International Nuclear Information System (INIS)

Broda, R.; Lesniak, L.; Malecki, P.; Stachura, Z.; Wojciechowski, H.

1992-01-01

The material presented describing the scientific activities of the Henryk Niewodniczanski Institute of Nuclear Physics in 1991 is the first annual report in several years.The arrangement of the report from various departments reflect the present structure of the Institute and is meant to help in the future task of reconstructing the Institute. Few guidelines proposed by the editorial board gave the individual departments much freedom in selecting the material and choosing the volume and format of presentation. (author)

Krytyka dziewiętnastowiecznego rozumu. Źródła i konteksty Pałuby Karola Irzykowskiego

OpenAIRE

Jauksz, Marcin

2010-01-01

Wydział Filologii Polskiej i Klasycznej: Instytut Filologii Polskiej The author interprets one of the crucial novels of the Young Poland in the context of prominent nineteenth and twentieth century literary works in order to show its prominent aspect – the fact of its being a document of its author experience. Due to the setting of The Hag alongside the literary pieces of Henryk Sienkiewicz, Stendhal, Stanisław Brzozowski, Edgar Alan Poe, Kazimierz Przerwa-Tetmajer and Wacław Berent and t...

Annual report 1993

International Nuclear Information System (INIS)

Bartke, J.; Erbel, D.; Fornal, B.; Friendl, L.; Grebosz, J.; Krygowska-Doniec, M.; Malecki, P.; Waligorski, M.; Wojciechowski, H.

1994-01-01

The material presented describing the research activities of the Henryk Niewodniczanski Institute of Nuclear Physics in 1993. The main directions of scientific investigation were: elementary particle physics, nuclear reaction end nuclear spectroscopy, physics of condensed matter applying nuclear methods, theoretical physics, nuclear geophysics and hydrology, radiobiology, radiochemistry, nuclear methods including NMR imaging, environmental studies with nuclear and nonnuclear methods, TLD dosimetry and several technical enterprises, such as the construction of particle accelerators, semiconductor detectors for low, intermediate and high energy physics, ion implantation and development of computer networks for scientific purposes

Annual report 1993

Energy Technology Data Exchange (ETDEWEB)

Bartke, J; Erbel, D; Fornal, B; Friendl, L; Grebosz, J; Krygowska-Doniec, M; Malecki, P; Waligorski, M; Wojciechowski, H [eds.

1994-12-31

The material presented describing the research activities of the Henryk Niewodniczanski Institute of Nuclear Physics in 1993. The main directions of scientific investigation were: elementary particle physics, nuclear reaction end nuclear spectroscopy, physics of condensed matter applying nuclear methods, theoretical physics, nuclear geophysics and hydrology, radiobiology, radiochemistry, nuclear methods including NMR imaging, environmental studies with nuclear and nonnuclear methods, TLD dosimetry and several technical enterprises, such as the construction of particle accelerators, semiconductor detectors for low, intermediate and high energy physics, ion implantation and development of computer networks for scientific purposes.

The New Edition of Chopin’s Correspondence

Directory of Open Access Journals (Sweden)

Helman-Bednarczyk Zofia

2016-12-01

Full Text Available Some of Fryderyk Chopin’s letters were published individually or in groups already in the 2nd half of the 19th century. With the passage of time, more letters from and to Chopin were printed in monographs dedicated to his life and work. The first editions of Chopin’s collected letters come from the 1st half of the 20th century (by Scharlitt and von Guttry in Germany, Henryk Opieński – in Poland. B.E. Sydow’s Fryderyk Chopin’s Correspondence of 1955 continues to be used as the basic source edition by Chopin biographers. It has many strong points, but has become largely outdated.

Effects of intravitreal ranibizumab on the untreated eye and systemic gene expression profile in age-related macular degeneration

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Michalska-Małecka K

2016-03-01

Full Text Available Katarzyna Michalska-Małecka,1,2 Adam Kabiesz,2 Malgorzata W Kimsa,3 Barbara Strzałka-Mrozik,3 Maria Formińska-Kapuścik,2,4 Malgorzata Nita,5 Urszula Mazurek31Clinical Department of Ophthalmology, Medical University of Silesia, Katowice, Poland; 2University Center for Ophthalmology and Oncology, Independent Public Clinical Hospital, Medical University of Silesia, Katowice, Poland; 3Department of Molecular Biology, School of Pharmacy with the Division of Laboratory Medicine in Sosnowiec, Medical University of Silesia, Katowice, Poland; 4Clinical Department of Children Ophthalmology, Medical University of Silesia, Katowice, Poland; 5Domestic and Specialized Medicine Centre “Dilmed”, Katowice, PolandAbstract: The purpose of this study was to evaluate the systemic effects of intravitreal ranibizumab (Lucentis treatment in patients with neovascular age-related macular degeneration (AMD. The impact of intravitreal ranibizumab injections on central retinal thickness (CRT of treated and contralateral untreated eyes, and differences in gene expression patterns in the peripheral blood mononuclear cells were analyzed. The study included 29 patients aged 50 years old and over with diagnosed neovascular AMD. The treatment was defined as 0.5 mg of ranibizumab injected intravitreally in the form of one injection every month during the period of 3 months. CRT was measured by optical coherence tomography. The gene expression profile was assigned using oligonucleotide microarrays of Affymetrix HG-U133A. Studies have shown that there was a change of CRT between treated and untreated eyes, and there were differences in CRT at baseline and after 1, 2, and 3 months of ranibizumab treatment. Three months after intravitreal injection, mean CRT was reduced in the treated eyes from 331.97±123.62 to 254.31±58.75 µm, while mean CRT in the untreated fellow eyes reduced from 251.07±40.29 to 235.45±36.21 µm at the same time. Furthermore, the research has shown

Dziedzictwo Wielkiego Księstwa Litewskiego i Kresów północno-wschodnich w świetle ustaleń językoznawstwa erudycyjnego

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Katarzyna Węgorowska

2014-12-01

Full Text Available Heritage of the Grand Duchy of Lithuania and the Polish Northeastern Borderlands in the light of erudite linguistics The essay contains reflections on the ways of using erudite linguistics, a young discipline created by me, in the study of the Grand Duchy of Lithuania and the Polish Northeastern Borderlands. Correlation of linguistic and extralinguistic conclusions (culture, history, art, gemology permits us to look in a new way at many facts of the Polish Northeastern Borderlands that linguists had not been interested in before, such as old Polish Northeastern Borderlands museum artifacts, jewelry of Grand Duchy of Lithuania, icon of Our Lady of the Gate of Dawn, cult of the dead in the Polish Northeastern Borderlands, architecture of the old Vilnius, manor house in Czombrów – the prototype of Soplicowo (the village in Pan Tadeusz epic poem, descriptions of Henryk Poddębski’s daguerreotype images, Vilnius identity of Henryk Szylkin or symbolic-figurative nicknames of Vilnius.   Dziedzictwo Wielkiego Księstwa Litewskiego i Kresów północno-wschodnich w świetle ustaleń językoznawstwa erudycyjnego Szkic jest refleksją o sposobach wykorzystywania stworzonego przeze mnie, kilkunastoletniego zaledwie, językoznawstwa erudycyjnego w badaniach nad problematyką wielkoksiążęcą i północnokresową. Korelacja ustaleń językoznawczych z ustaleniami pozajęzykowymi (kultura, historia, sztuka, gemmologia… pozwoliła na nowe odczytanie wielu kresowych faktów, które nie były dotąd  przedmiotem zainteresowania językoznawców, jak np.: artefakty dawnych północnokresowych muzeów, wielkoksiążęce precjoza, Ikona Ostrobramska, północnokresowy kult zmarłych, architektura dawnego Wilna, prototyp Soplicowa – dwór w Czombrowie, opisy dagerotypów Henryka Poddębskiego, wileńska tożsamość Henryka Szylkina czy symboliczno-metaforyczne nazwy Wilna.

Annual report 1994

Energy Technology Data Exchange (ETDEWEB)

Bartke, J.; Erbel, D.; Freindl, L.; Krupinski, W.; Krygowska-Doniec, M.; Lekki, J.; Malecki, P.; Wojciechowski, H. [eds.

1995-12-31

The material presented describes the research activities of the Henryk Niewodniczanski Institute of Nuclear Physics in 1993. The main directions of scientific investigation were: nuclear reaction, nuclear spectroscopy, physics of condensed matter applying nuclear methods, theoretical physics, high energy physics, environmental and radiation transport physics, radiation and environmental biology, nuclear radio spectroscopy,nuclear physical chemistry, health physic. Technical enterprises, such as the construction of particle accelerators, detectors and electronics for low, intermediate and high energy physics, ion implantation and development of computer networks for scientific purposes. The report consist of 11 sections, each of them describes the activity of one among INP laboratories. Additionally an information as lists of personnel, publications, contributions to conferences, reports, seminars is presented. An introduction written by General Director of INP professor A. Budzanowski is also given.

Annual report 1994

Energy Technology Data Exchange (ETDEWEB)

Bartke, J; Erbel, D; Freindl, L; Krupinski, W; Krygowska-Doniec, M; Lekki, J; Malecki, P; Wojciechowski, H [eds.

1996-12-31

The material presented describes the research activities of the Henryk Niewodniczanski Institute of Nuclear Physics in 1993. The main directions of scientific investigation were: nuclear reaction, nuclear spectroscopy, physics of condensed matter applying nuclear methods, theoretical physics, high energy physics, environmental and radiation transport physics, radiation and environmental biology, nuclear radio spectroscopy,nuclear physical chemistry, health physic. Technical enterprises, such as the construction of particle accelerators, detectors and electronics for low, intermediate and high energy physics, ion implantation and development of computer networks for scientific purposes. The report consist of 11 sections, each of them describes the activity of one among INP laboratories. Additionally an information as lists of personnel, publications, contributions to conferences, reports, seminars is presented. An introduction written by General Director of INP professor A. Budzanowski is also given.

Annual report 1994

International Nuclear Information System (INIS)

Bartke, J.; Erbel, D.; Freindl, L.; Krupinski, W.; Krygowska-Doniec, M.; Lekki, J.; Malecki, P.; Wojciechowski, H.

1995-01-01

The material presented describes the research activities of the Henryk Niewodniczanski Institute of Nuclear Physics in 1993. The main directions of scientific investigation were: nuclear reaction, nuclear spectroscopy, physics of condensed matter applying nuclear methods, theoretical physics, high energy physics, environmental and radiation transport physics, radiation and environmental biology, nuclear radio spectroscopy,nuclear physical chemistry, health physic. Technical enterprises, such as the construction of particle accelerators, detectors and electronics for low, intermediate and high energy physics, ion implantation and development of computer networks for scientific purposes. The report consist of 11 sections, each of them describes the activity of one among INP laboratories. Additionally an information as lists of personnel, publications, contributions to conferences, reports, seminars is presented. An introduction written by General Director of INP professor A. Budzanowski is also given

Contribution IFJ PAN to the construction of the Wendelstein 7-X stellarator (2008 - 2009)

International Nuclear Information System (INIS)

Blocki, J.; Hajduk, L.; Kotula, J.; Stodulski, M.; Sulek, Z.

2010-05-01

The Wendelstein 7-X stellarator is now being assembled at the Max Planck Institute for Plasma Physic (IPP), Greifswald, Germany. The Agreement on Cooperation between the Max-Planck-Institut fur Plasmaphysik in Garching and the Henryk Niewodniczanski Institute of Nuclear Physics Polish Academy of Sciences in Krakow (IFJ PAN) was signed off in 2007. The intention of the agreement is to cover the whole period of the W7-X construction. According to the agreement IFJ PAN has taken over the following tasks: 1. to assembly of the bus bar system powering the superconducting coils of the stellarator; 2. to take part in design of equipment used during handling, transportation and assembly of outer vessels; 3. to manufacture 30 polichromators used for plasma diagnostics. Task No 2 was completed in 2008 while tasks No 1 and 3 are to be continued. (authors)

23 February 2010 - Polish Under Secretary of State, Ministry of Science and Higher Education, J. Szwed visiting CERN installations with sLHC Project Office T. Kurtyka and Machine Protection and Electrical Integrity Group Leader A. Siemko.

CERN Multimedia

Michel Blanc

2010-01-01

Tirage 1002023-01: In LHCb experimental area with Machine Protection and Electrical Integrity Group Leader A. Siemko; Mission Counselor M. Cichucka; Counselor to the Minister M. Klimkiewicz, Under Secretary of State J. Szwed; LHCb Collaboration, national group leader, Henryk Niewodniczanski Institut of Nuclear Physics G. Polok, Collaboration Spokesperson A. Golutvin and Delegate to CERN Council A. Zalewska. Tirage 28: Visiting the Computing Centre with IT Department Head F. Hemmer Tirage 49: In CMS Control centre, buiding 354 with Collaboration Spokesperson G. Tonelli and CMS Collaboration, national group leader, University of Warsaw J. Krolikowski. Tirage 62: visiting ALICE exhibition area and counting room with Collaboration Spokesperson J. Schukraft. Tirage 82-99: Under Secretary of State address to the Polish Community Tirage 82: Machine Protection and Electrical Integrity Group Leader A. Siemko Tirage 83: Polish Delegate to CERN Council A. Zalewska. Tirage 85: Directorate Office E. Rondio Tirage 86: ATLA...

“Wildness” as a metaphor for self-definition of the colonised subject in the Positivist period in Poland

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Anna Kołos

2011-06-01

Full Text Available This article discusses the question of the Polish nation's self-definition in the Positivist period both in belles-lettres and in journalism, which were dependent to a great extent on the colonial discourse. It is argued that crucial metaphors of “wildness,” “savageness” or “backwardness” stem from orientalising labels created by the colonisers. Examination of this issue requires some basic introduction to historical and anthropological ideas which date back to the Age of Enlightenment. The aim of this paper is to shed light – by analysing literature examples such as Ludwik Powidaj, Cyprian Kamil Norwid, Maria Konopnicka, Eliza Orzeszkowa and Henryk Sienkiewicz – on the so called “colonial trauma” that has condemned the Polish image to resentful ideology. Furthermore, the paper will provide arguments in favour of subscribing to the postcolonial studies in Central and Eastern Europe.

Z dziejów akcji antykomunistycznej w Polsce : miesięcznik "Walka z Bolszewizmem" w latach 1927-1931

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Arkadiusz Meller

2015-10-01

Full Text Available Critical reflections over marxist ideology, and especially political system in the USSR, were present in the polish political thought in the first half of the XXth century, due to publications, among others, by Adam Krzyżanowski, Stanisław Mackiewicz or Marian Zdziechowski. An important role in spreading anti-communist ideas played magazine “Fight with bolshevism” established in 1927 by Henryk Glass. The main task of the editorial board was to inform the Polish nation about the threats coming out from communism. To fulfill this task, magazine published official papers of the Communist International, communist parties, soviet government etc., along with some communist confidential materials. “Fight with bolshevism” used all possible means to warn the society of the danger coming from the east. The author talks over the most important problems and topics took up by the magazine, as well as the social undertakings supported by it.

Highly biocompatible, nanocrystalline hydroxyapatite synthesized in a solvothermal process driven by high energy density microwave radiation

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Smolen D

2013-02-01

Full Text Available Dariusz Smolen1, Tadeusz Chudoba1, Iwona Malka1, Aleksandra Kedzierska1, Witold Lojkowski1, Wojciech Swieszkowski2, Krzysztof Jan Kurzydlowski2, Malgorzata Kolodziejczyk-Mierzynska3, Malgorzata Lewandowska-Szumiel31Polish Academy of Science, Institute of High Pressure Physics, Warsaw, Poland; 2Faculty of Materials Engineering, Warsaw University of Technology, Warsaw, Poland; 3Department of Histology and Embryology, Center of Biostructure Research, Medical University of Warsaw, Warsaw, PolandAbstract: A microwave, solvothermal synthesis of highly biocompatible hydroxyapatite (HAp nanopowder was developed. The process was conducted in a microwave radiation field having a high energy density of 5 W/mL and over a time less than 2 minutes. The sample measurements included: powder X-ray diffraction, density, specific surface area, and chemical composition. The morphology and structure were investigated by scanning electron microscopy as well as transmission electron microscopy (TEM. The thermal behavior analysis was conducted using a simultaneous thermal analysis technique coupled with quadruple mass spectrometry. Additionally, Fourier transform infrared spectroscopy tests of heated samples were performed. A degradation test and a biocompatibility study in vitro using human osteoblast cells were also conducted. The developed method enables the synthesis of pure, fully crystalline hexagonal HAp nanopowder with a specific surface area close to 240 m2/g and a Ca/P molar ratio equal to 1.57. TEM measurements showed that this method results in particles with an average grain size below 6 nm. A 28-day degradation test conducted according to the ISO standard indicated a 22% loss of initial weight and a calcium ion concentration at 200 µmol/dm3 in the tris(hydroxymethylaminomethane hydrochloride test solution. The cytocompatibility of the obtained material was confirmed in a culture of human bone derived cells, both in an indirect test using the material

Design and characteristics of cytotoxic fibroblast growth factor 1 conjugate for fibroblast growth factor receptor-targeted cancer therapy

Directory of Open Access Journals (Sweden)

Szlachcic A

2016-08-01

Full Text Available Anna Szlachcic, Malgorzata Zakrzewska, Michal Lobocki, Piotr Jakimowicz, Jacek Otlewski Department of Protein Engineering, Faculty of Biotechnology, University of Wroclaw, Wroclaw, Poland Abstract: Fibroblast growth factor receptors (FGFRs are attractive candidate cancer therapy targets as they are overexpressed in multiple types of tumors, such as breast, prostate, bladder, and lung cancer. In this study, a natural ligand of FGFR, an engineered variant of fibroblast growth factor 1 (FGF1V, was conjugated to a potent cytotoxic drug, monomethyl auristatin E (MMAE, and used as a targeting agent for cancer cells overexpressing FGFRs, similar to antibodies in antibody–drug conjugates. The FGF1V–valine–citrulline–MMAE conjugate showed a favorable stability profile, bound FGFRs on the cell surface specifically, and efficiently released the drug (MMAE upon cleavage by the lysosomal protease cathepsin B. Importantly, the conjugate showed a prominent cytotoxic effect toward cell lines expressing FGFR. FGF1V–vcMMAE was highly cytotoxic at concentrations even an order of magnitude lower than those found for free MMAE. This effect was FGFR-specific as cells lacking FGFR did not show any increased mortality. Keywords: fibroblast growth factor 1, FGF receptor, targeted cancer therapy, cytotoxic conjugates, FGFR-dependent cancer, MMAE, auristatin

Limnological characterization of freshwater systems of the Thomas Point Oasis (Admiralty Bay, King George Island, West Antarctica)

Science.gov (United States)

Nędzarek, Arkadiusz; Pociecha, Agnieszka

2010-12-01

Hydrochemical research into the small, shallow water bodies and wetland areas around the Henryk Arctowski Polish Antarctic Station (King George Island) is presented. Concentrations of nitrite, nitrate, ammonium, and total nitrogen in these waters were determined, as were those of reactive and total phosphorous, inorganic carbon, organic carbon, total carbon, silicate, and chloride and sulfate ions. Conductivity and pH were also measured. Average concentrations ranged widely, e.g., total nitrogen 0.176-29.21 mg L -1, total phosphorus 0.022-18.35 mg L -1, total carbon 1.38-26.90 mg L -1, Cl - 30.17-850 mg L -1, and SO 42- 2.11-236 mg L -1. The trophic status was influenced by influxes of nitrogen and phosphorus from penguin rookeries. Selected water bodies supported 31 taxa of algae and 11 invertebrate taxa, with Euglenophyta dominating in waters with high concentrations of ammonium-nitrogen, whereas diatoms characterized Lake Wujka, with low ammonium concentrations. All water bodies studied had rotifers, but crustaceans were only represented in Lake Wujka.

Book of Abstracts - International Conference 'Radon in Environment', Zakopane, 10-14 May 2009

International Nuclear Information System (INIS)

Mazur, J.; Kozak, K.; Kobol, I.

2009-04-01

The Henryk Niewodniczanski Institute of Nuclear Physics, Polish Academy of Sciences has been organizing since 2000 the serial conferences, traditionally called RADON IN ENVIRONMENT. This is the first international meeting, two previous conferences (in 2000 and 2005) were national. The conference covers the following topics: · radon and thoron in air, water and soil, · modelling of radon transport, · geological aspects, · measurement techniques and interpretation of results, · techniques of reducing radon concentrations, · health aspects, · protection against radon risk, · uranium and thorium series, · NORM and TENORM elements in environment, · law regulations, · information policy. The Conference takes place in Zakopane (southern part of Poland, about 100 km distance from Krakow) at the conference and holiday centre '' ANTALOWKA ''. Zakopane, beautifully situated at the foot of the Tatra mountains, offers a chance to take advantage of outdoor recreation and to become acquainted with the unique folklore of the local mountaineers. We do hope that the conference will provide a forum to explore and discuss new scientific initiatives and all participants will benefit from this meeting. (author)

A tough truck for ATLAS

CERN Multimedia

2003-01-01

One of the mobile support structures that will be used to manoeuvre and assemble components of the ATLAS detector in its cavern was put through its paces at the end of July and passed its load tests with flying colours. The tests, which involved the surveyors taking measurements to detect any load-induced mechanical deformations, were carried out in Building 191. "The "truck" has been subjected to static tests with loads of up to 1250 tonnes and can carry and transport on air cushions a nominal load of up to 1000 tonnes at a top speed of 30 cm per minute," explains project leader Tommi Nyman. "It took two weeks to assemble the truck's components, the last of which arrived at CERN on 24 June. It then took a further 20 days to load the truck up for the test." The 8.5 metre-high truck will be used for final assembly of some of the ATLAS components, including the calorimeters, in cavern UX15. This powerful device is the result of a collaboration between CERN and the Henryk Niewodniczanski Institute of Nuclear ...

Between Connotation and Denotation. Posters Announcing the Warsaw Autumn International Festival of Contemporary Music in 1956-2015

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Knorowski Mariusz

2017-12-01

Full Text Available The posters that accompany the successive Warsaw Autumn Festival editions are a unique collection of works, mostly of outstanding quality. One might venture the thesis that their artistic value – living up to the high demands of the topic – exceeds the typical standards of representation characteristic of popular art. Formally speaking, they abandon the conventions of egalitarian iconographic art in favour of a more elite-oriented visual formula, addressed to a competent audience knowledgeable about contemporary music and its qualities. The authors of these WA posters include many artists associated with the Polish school, such as Jan Lenica, Jan Młodożeniec, Julian Pałka, Waldemar Świerzy, Henryk Tomaszewski, and Wojciech Zamecznik. Their graphic representations of the achievements of the musical avant-garde do not, however, situate this poster series within the well-sanctioned canon of the “Polish poster school”, mostly associated with the film and theatre – generally considered as more “democratic” and entertainment-oriented disciplines of art.

Barnkonventionens föregångare. Anteckningar om den polske barnläkaren och pedagogen Janusz Korczak

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Sven G Hartman

2001-01-01

Full Text Available The Polish paediatrician and educationalist Janusz Korczak ( Henryk Goldszmit 1878-1942 is one of the great names in the progressive wave in the decades around the First World War. International interest in Korczak is focusing on his many-sided work as an author, physician, educationalist and advocate of children’s rights. He was also one of the martyrs of the Holocaust. His work is one of the inspirations of the UN Convention on the Rights of Children. This paper focuses on different professional dimensions of educational work as described by Korczak: practice, basic values and educational science. It also deals with Korczak as a typical representative of modernity in medicine and education. Zygmunt Bauman’s view on modernity and Holocaust is applied on Korczak’s work. You can find similarities between Korczak and the Nazi doctors, for instance. But there is also a crucial difference connected to the moral dimensions of professional work. Respect for humanity and respect for children is a fundamental principal in the writings of Korczak. His thoughts about children’s right to respect are original and still worth reading.

Hydrogeological characteristics of aquifer near Arctowski Polish Antarctic Station on King George Island (South Shetland Islands), Antarctica

Science.gov (United States)

Krogulec, Ewa; Krogulec, Tomasz; Małecki, Jerzy; Pietrzykowski, Paweł; Dobak, Paweł

2018-06-01

During the Antarctic summer season of 2015/2016, the groundwater studies were performed in the area of Henryk Arctowski Polish Antarctic Station on King George Island (South Shetland Islands) in Admiralty Bay of Antarctica. Rock and groundwater samples were collected from 14 research excavations down to a depth of 0.8-2.5 m b.g.l. Analyses of surface waters were performed on water samples from streams, mossland, and a drinking water reservoir. The scope of hydrochemical studies comprised analyses of temperature, pH, mineralization, phosphates, nitrates, macroelements and selected microelements. Using empirical formulas, granulometric analysis of rock samples from various depths, measurements of sample moisture, and calculations of the hydraulic conductivity were performed. The groundwater is poorly mineralized, representing chloride-sulfate-bicarbonate-sodium and chloride-bicarbonate-sodium-calcium types. Studies on hydrochemical indicators show a small range of the effect of animal ecosystems on the waters; no effects of organic matter have been identified in the study area. Results of hydrogeochemical studies of waters and observations of groundwater levels in the summer season indicate groundwater recharge in a shallow groundwater circulation system, lateral inflow direction from land toward the seashore, and a low rate of rainwater infiltration. Groundwater drainage occurs through evapotranspiration and water runoff to the sea.

75 FR 43807 - Airworthiness Directives; Zaklad Szybo wcowy “Jeżów” Henryk Mynarski Model PW-6U Sailplanes

Science.gov (United States)

2010-07-27

...: Cracks on the lug of the rear attachment fitting of the horizontal stabilizer have been detected during..., Kansas City, Missouri 64106; telephone: (816) 329-4130; fax: (816) 329-4090. SUPPLEMENTARY INFORMATION... lug of the rear attachment fitting of the horizontal stabilizer have been detected during the...

Committees and organizers

Science.gov (United States)

2011-07-01

Chairman:Jozef Spałek (Kraków) Program Committee:Stephen Blundell (Oxford), J Michael D Coey (Dublin), Dominique Givord (Grenoble), Dariusz Kaczorowski (Wrocław), Roman Micnas (Poznań), Marek Przybylski (Halle), Ludiwig Schultz (Dresden), Vladimir Sechovsky (Prague), Jozef Spałek (Kraków), Henryk Szymczak (Warszawa), Manuel Vázquez (Madrid) Publication Committee:Dariusz Kaczorowski, Robert Podsiadły, Jozef Spałek, Henryk Szymczak, Andrzej Szytuła Local committee:Maria Bałanda, Anna Majcher, Robert Podsiadły, Michał Rams, Andrzej Ślebarski, Krzysztof Tomala Editors of the Proceedings:Jozef Spałek, Krzysztof Tomala, Danuta Goc-Jagło, Robert Podsiadły, Michał Rams, Anna Majcher Plenary, semi-plenary and tutorial speakers:Ernst Bauer (Wien)Stephen Blundell (Oxford)J Michael D Coey (Dublin)Russell P Cowburn (London)Burkard Hillebrands (Kaiserslautern)Claudine Lacroix (Grenoble)Lluís Mañosa (Barcelona)María del Carmen Muñoz (Madrid)Bernard Raveau (Caen)Pedro Schlottmann (Tallahassee)Frank Steglich (Dresden)Oliver Waldmann (Freiburg) Invited speakers within symposia: R Ahuja (Uppsala)A Kirilyuk (Nijmegen) M Albrecht (Vienna)L Theil Kuhn (Roskilde) K Bärner (Göttingen)J Liu (Dresden) U Bovensiepen (Duisburg)G Lorusso (Modena) V Buchelnikov (Chelyabinsk)M M Maska (Katowice) B Chevalier (Bordeaux)Y Mukovskii (Moscow) O Chubykalo-Fesenko (Madrid)M Pannetier-Lecoeur (Saclay) A V Chumak (Kaiserslautern)G Papavassiliou (Athens) J M D Coey (Dublin)K R Pirota (Campinas) B Dabrowski (DeKalb)P Przyslupski (Warszawa) S Das (Aveiro)M Reiffers (Košice) A del Moral (Zaragoza)K Sandeman (London) V E Demidov (Muenster)D Sander (Halle) B Djafari-Rouhani (Lille)M Sawicki (Sendai/Warsaw) H A Dürr (Menlo Park)J Schaefer (Würzburg) J Fassbender (Dresden)H Schmidt (Wetzikon) J Fontcuberta (Barcelona)J Spałek (Kraków) V Garcia (Orsay)L Straka (Helsinki) J N Gonçalves (Aveiro)A Szewczyk (Warszawa) M E Gruner (Duisburg)Y Taguchi (Wako) G Gubbiotti (Perugia)A Thiaville

İKİ POLONYALI GRAFİK TASARIMCI-HENRYK TOMASZEWSKI VE FRANCİSZEK STAROWİEYSKİ-ÖRNEĞİNDE II. DÜNYA SAVAŞI SONRASI TİYATRO AFİŞLERİ/THEATRE POSTERS AFTER THE SECOND WORLD WAR FROM TWO POLISH GRAPHIC DESIGNERS -HENRYK TOMASZEWSKI VE FRANCISZEK STAROWIEYSKI-A

OpenAIRE

Gümüştekin, Nuray

2012-01-01

ÖZETBu araştırmanın amacı, grafik tasarım tarihinde, tasarımcılarının az rastlanır bir fırsata sahip olduğu Polonya’da afiş tasarımcılarının, tiyatro afiş tasarımlarını içerik ve renk boyutunda incelemektir. Polonya’nın bu anlamda ayrıcalıklı bir yere sahip olması bu araştırmanın yapılmasında oldukça etkili olmuştur. Araştırmanın içeriğinde tiyatro sanatına eklenen afiş bir grafik tasarım ürünü olarak kendi değerleri içinde aç...

Dormancy in breast cancer

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Banys M

2012-12-01

Full Text Available Malgorzata Banys,1,2 Andreas D Hartkopf,1 Natalia Krawczyk,1 Tatjana Kaiser,1 Franziska Meier-Stiegen,1 Tanja Fehm,1 Hans Neubauer11Department of Obstetrics and Gynecology, University of Tuebingen, Tuebingen, Germany; 2Department of Obstetrics and Gynecology, Marienkrankenhaus Hamburg, Hamburg, GermanyAbstract: Tumor dormancy describes a prolonged quiescent state in which tumor cells are present, but disease progression is not yet clinically apparent. Breast cancer is especially known for long asymptomatic periods, up to 25 years, with no evidence of the disease, followed by a relapse. Factors that determine the cell's decision to enter a dormant state and that control its duration remain unclear. In recent years, considerable progress has been made in understanding how tumor cells circulating in the blood interact and extravasate into secondary sites and which factors might determine whether these cells survive, remain dormant, or become macrometastases. The mechanisms of tumor cell dormancy are still not clear. Two different hypotheses are currently discussed: tumor cells persist either by completely withdrawing from the cell cycle or by continuing to proliferate at a slow rate that is counterbalanced by cell death. Because dormant disseminated tumor cells may be the founders of metastasis, one hypothesis is that dormant tumor cells, or at least a fraction of them, share stem cell-like characteristics that may be responsible for their long half-lives and their suggested resistance to standard chemotherapy. Therefore, knowledge of the biology of tumor cell dormancy may be the basis from which to develop innovative targeted therapies to control or eliminate this tumor cell fraction. In this review, we discuss biological mechanisms and clinical implications of tumor dormancy in breast cancer patients.Keywords: tumor dormancy, disseminated tumor cell, circulating tumor cell, targeted therapy

Protection of Children's Human Rights and Health: A Legacy of Julian Kramsztyk, Janusz Korczak, and Ludwik Rajchman.

Science.gov (United States)

Woltanowski, Piotr; Wincewicz, Andrzej; Sulkowski, Stanisław

2018-01-01

Tutor of generations of Warsaw medical doctors, Julian Kramsztyk (1851-1926) was son of Rabbi Izaak Kramsztyk, Polish patriot and fighter for independent Poland. Julian Kramsztyk graduated in medicine from Warsaw University in 1873 to soon work as a supervisor of the Internal Diseases Department of Bersohns and Baumans Children's Hospital from 1878 to 1910, and despite of refusing professorship from Imperial Warsaw University, he worked as a lecturer of pediatric disorders from 1880 with strong association of his medical practice with scientific and editorial tasks as well as engaging in charity. This article focuses on selective retrieval of biographical data of social and scientific achievements of followers of Julian Kramsztyk: his student, pioneer of children human rights, and pioneer of healthy patterns of nutrition of children, pediatrician Janusz Korczak (Henryk Goldszmit; 1878 or 1879-1942); and a skilled bacteriologist and a brilliant epidemiologist who was a prominent activist of the League of Nations (later United Nations Organization), cofounder of the UNICEF (United Nations Children's Emergency Fund), and the first chairman of the Organization from 1946 to 1950, which was primarily dedicated to "provide emergency food and health care to children in postwar time," Ludwik Rajchman (1881-1965). Janusz Korczak works laid foundation for international recognition of children rights to health, respect, education, privacy, and all the other human rights to be included in the United Nations Convention on the Rights of the Child (UNCRC). In 1989, nutrition and vaccination issues were the main medical interests of these medical doctors and still remain major fields of UNICEF actions.

Fast-degrading PLA/ORMOGLASS fibrous composite scaffold leads to a calcium-rich angiogenic environment

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Sachot N

2017-07-01

Full Text Available Nadège Sachot,1,2 Agata Roguska,3 Josep Anton Planell,1,2 Malgorzata Lewandowska,3 Elisabeth Engel,1,2,4 Oscar Castaño1,2,5,6 1Biomaterials for Regenerative Therapies, Institute for Bioengineering of Catalonia (IBEC, Barcelona, 2CIBER en Bioingeniería, Biomateriales y Nanomedicina, CIBER-BBN, Zaragoza, Spain; 3Faculty of Materials Science and Engineering, Warsaw University of Technology, Warsaw, Poland; 4Department of Materials Science and Metallurgical Engineering, Universitat Politècnica de Catalunya (UPC, 5Department of Materials Science and Physical Chemistry, Universitat de Barcelona (UB, 6Department of Engineerings: Electronics, Universitat de Barcelona, Barcelona, Spain Abstract: The success of scaffold implantation in acellular tissue engineering approaches relies on the ability of the material to interact properly with the biological environment. This behavior mainly depends on the design of the graft surface and, more precisely, on its capacity to biodegrade in a well-defined manner (nature of ions released, surface-to-volume ratio, dissolution profile of this release, rate of material resorption, and preservation of mechanical properties. The assessment of the biological behavior of temporary templates is therefore very important in tissue engineering, especially for composites, which usually exhibit complicated degradation behavior. Here, blended polylactic acid (PLA calcium phosphate ORMOGLASS (organically modified glass nanofibrous mats have been incubated up to 4 weeks in physiological simulated conditions, and their morphological, topographical, and chemical changes have been investigated. The results showed that a significant loss of inorganic phase occurred at the beginning of the immersion and the ORMOGLASS maintained a stable composition afterward throughout the degradation period. As a whole, the nanostructured scaffolds underwent fast and heterogeneous degradation. This study reveals that an angiogenic calcium

Analysis of the relationships between edentulism, periodontal health, body composition, and bone mineral density in elderly women

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Ignasiak Z

2016-03-01

Full Text Available Zofia Ignasiak,1 Malgorzata Radwan-Oczko,2 Krystyna Rozek-Piechura,3 Marta Cholewa,4 Anna Skrzek,5 Tomasz Ignasiak,6 Teresa Slawinska1 1Department of Biostructure, University School of Physical Education, Wroclaw, Poland; 2Department of Periodontology, Wroclaw Medical University, Wroclaw, Poland; 3Department of Physiotherapy and Occupation Therapy in Internal Diseases, University School of Physical Education, Wroclaw, Poland; 4DENTARAMA Dentistry Center, Walbrzych, Poland; 5Department of Physiotherapy and Ocupation Therapy in Motor-System Dysfunction, University School of Physical Education, Wroclaw, Poland; 6Karkonosze State Higher School in Jelenia Gora, Jelenia Gora, Poland Objective: The relationship between bone mineral density (BMD and tooth loss in conjunction with periodontal disease is not clear. The suggested effects include alteration in bone remodeling rates as well as the multifaceted etiology of edentulism. There is also a question if other body-related variables besides BMD, such as body composition, may be associated with tooth number and general periodontal health. The aim of this study was to evaluate if tooth number and marginal periodontal status are associated with body composition and BMD in a sample of elderly women. Materials and methods: The study involved 91 postmenopausal women. Data included basic anthropometric characteristics, body composition via bioelectrical impedance analysis, and BMD analysis at the distal end of the radial bone of the nondominant arm via peripheral dual-energy X-ray absorptiometry. A dental examination was performed to assess tooth number, periodontal pocket depth (PD, and gingival bleeding. Results: In nonosteoporotic women, a significant positive correlation was found between BMD and lean body mass, total body water, and muscle mass. The indicators of bone metabolism correlated negatively with PD. Such relationships did not appear in osteoporotic women. In both groups, basic anthropometric

Is the Unspeakable Singable? The Ethics of Holocaust Representation and the Reception of Górecki's Symphony no.3

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Alison Moore

2011-09-01

Full Text Available Debates about Holocaust representation have long been haunted by the idea that the enormity and intensity of human suffering in the events of World War Two are ‘unspeakable’. In many such statements the capacity for cognition and the ethical dimension of aestheticisation are blurred – the Holocaust is ‘unspeakable’ both in the sense of being impossible to imagine in its full horror, but also morally inappropriate as the subject of artistic production. But do all forms of cultural representation of the Holocaust fail in the same way as words or to the same degree, in the eyes of those who would judge their merits according the tenet of unspeakability? This paper considers one particularly renowned work Henryk Górecki’s symphony no. 3 (Symfonia pieśni żałosnych of 1976, discussing how it mediated both the global politics of Holocaust representation and the recuperation of victimhood in postcommunist Poland. Górecki claimed a subjectivity of failure in response to the challenge of representing the events of World War Two and has insisted that the symphony is not about war but about sorrow. The vocal lyrics are nonetheless profoundly thematised around war suffering, and the Second World War in particular - events he approached with a musical language of epic, pathos and redemption. In framing the subject of his work, he emphasised a Polish national suffering that both eschewed mention of specifically targeted groups of victims, and beckoned to Polish folk and catholic traditions. This article presents a new hypothesis about the success of Górecki’s work by considering it in relation to the ethical debates about Holocaust empathic response that have occurred in relation to historiographic, literary and filmic representation.

Department of Nuclear Spectroscopy - Overview

International Nuclear Information System (INIS)

Styczen, J.

2002-01-01

Full text: The Nuclear Spectroscopy Department is the largest department of the Institute. It merges a variety of research groups having been performing investigations with a rich diversity of methods: from pure studies of the structure of nucleus and of nuclear properties through applied nuclear spectroscopy in condensed matter research, to the complex biophysical investigations of biological tissues. The nuclear structure experiments were performed mainly in European Large Scale Facilities (ALPIINFN-Legnaro, VIVITRON-IReS-Strasbourg, JYFL-K100-Cyclotron) with the use of the GASP, EUROBALL IV, RITU systems and with application of ancillary detectors - HECTOR+HELENA, RFD. Some data were obtained with the GAMMASPHERE in USA. Other research has been based on our own instrumentation - VdG, AFM, Dual-Beam-Implanter, PAC, Moessbauer spectrometers etc., in a strong co-operation with Polish and European institutions, of course. The atomic studies were done on the ESR at GSI in Darmastadt. In several pages which follow, some important results of the investigations in the Department are presented. In 2001, Dr hab. Jerzy Dryzek and Dr hab. Adam Maj were granted the Associated Professor positions, and Miss Agnieszka Kulinska and Mrs Maria Kmiecik - the Ph.D. degrees. Dr Kmiecik was also awarded the Henryk Niewodniczanski prize for studies of 147 Eu compound nucleus shape evolution. Some of us became (continued to be) members of International Committees - the PHINUFY (R. Broda), the Steering Committee of RISING at GSI (J. Styczen), the PAC of the VIVITRON at Strasbourg (J. Styczen). We organized an International Conference on Condensed Matter Studies (100 participants), which belonged to the well known series of Zakopane School of Physics. It's Proceedings appeared as a volume of the Acta Physica Polonica A journal. (author)

Inflammatory etiopathogenesis of systemic lupus erythematosus: an update

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Podolska MJ

2015-08-01

Full Text Available Malgorzata J Podolska, Mona HC Biermann, Christian Maueröder, Jonas Hahn, Martin Herrmann Department of Internal Medicine 3, Institute for Clinical Immunology and Rheumatology, Friedrich-Alexander University of Erlangen-Nuremberg, Erlangen, Germany Abstract: The immune system struggles every day between responding to foreign antigens and tolerating self-antigens to delicately maintain tissue homeostasis. If self-tolerance is broken, the development of autoimmunity can be the consequence, as it is in the case of the chronic inflammatory autoimmune disease systemic lupus erythematosus (SLE. SLE is considered to be a multifactorial disease comprising various processes and cell types that act abnormally and in a harmful way. Oxidative stress, infections, or, in general, tissue injury are accompanied by massive cellular demise. Several processes such as apoptosis, necrosis, or NETosis (formation of Neutrophil Extracellular Traps [NETs] may occur alone or in combination. If clearance of dead cells is insufficient, cellular debris may accumulate and trigger inflammation and leakage of cytoplasmic and nuclear autoantigens like ribonucleoproteins, DNA, or histones. Inadequate removal of cellular remnants in the germinal centers of secondary lymphoid organs may result in the presentation of autoantigens by follicular dendritic cells to autoreactive B cells that had been generated by chance during the process of somatic hypermutation (loss of peripheral tolerance. The improper exposure of nuclear autoantigens in this delicate location is consequently prone to break self-tolerance to nuclear autoantigens. Indeed, the germline variants of autoantibodies often do not show autoreactivity. The subsequent production of autoantibodies plays a critical role in the development of the complex immunological disorder fostering SLE. Immune complexes composed of cell-derived autoantigens and autoantibodies are formed and get deposited in various tissues, such as the

Diet-induced metabolic hamster model of nonalcoholic fatty liver disease

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Bhathena J

2011-06-01

Full Text Available Jasmine Bhathena, Arun Kulamarva, Christopher Martoni, Aleksandra Malgorzata Urbanska, Meenakshi Malhotra, Arghya Paul, Satya PrakashBiomedical Technology and Cell Therapy Research Laboratory, Department of Biomedical Engineering, Artificial Cells and Organs Research Centre, Faculty of Medicine, McGill University, Montreal, Québec, CanadaBackground: Obesity, hypercholesterolemia, elevated triglycerides, and type 2 diabetes are major risk factors for metabolic syndrome. Hamsters, unlike rats or mice, respond well to diet-induced obesity, increase body mass and adiposity on group housing, and increase food intake due to social confrontation-induced stress. They have a cardiovascular and hepatic system similar to that of humans, and can thus be a useful model for human pathophysiology.Methods: Experiments were planned to develop a diet-induced Bio F1B Golden Syrian hamster model of dyslipidemia and associated nonalcoholic fatty liver disease in the metabolic syndrome. Hamsters were fed a normal control diet, a high-fat/high-cholesterol diet, a high-fat/high-cholesterol/methionine-deficient/choline-devoid diet, and a high-fat/high-cholesterol/choline-deficient diet. Serum total cholesterol, high-density lipoprotein cholesterol, low-density lipoprotein cholesterol, triglycerides, glucose, atherogenic index, and body weight were quantified biweekly. Fat deposition in the liver was observed and assessed following lipid staining with hematoxylin and eosin and with oil red O.Results: In this study, we established a diet-induced Bio F1B Golden Syrian hamster model for studying dyslipidemia and associated nonalcoholic fatty liver disease in the metabolic syndrome. Hyperlipidemia and elevated serum glucose concentrations were induced using this diet. Atherogenic index was elevated, increasing the risk for a cardiovascular event. Histological analysis of liver specimens at the end of four weeks showed increased fat deposition in the liver of animals fed

Actualité du roman archéologique

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Philippe Dufour

2009-01-01

Full Text Available Salammbô a beau se passer au IIIe siècle avant Jésus-Christ, Flaubert a beau y voir une ressource pour fuir le monde moderne, le roman antique n’en pense pas moins l’Histoire contemporaine, au moins par intermittence. On essaie de le montrer à propos d’un court fragment rescapé du chapitre explicatif, la description des assemblées des Syssites. Loin de démarquer simplement telle ou telle source (comme l’analyse aristotélicienne de la constitution carthaginoise dans La Politique, le paragraphe décrivant le banquet des Riches pendant que les Barbares entourent la ville évoque en surimpression la fête impériale sur fond de peur sociale. Des images relais (Les Romains de la décadence de Thomas Couture, Les Châtiments de Victor Hugo incitent le premier public à une lecture allégorique. Le chronotope de l’assemblée dénonce l’illusion d’un pouvoir et figure le devenir historique. Flaubert s’approprie ainsi de façon originale le genre du roman archéologique tel que l’abbé Barthélemy l’inventa ou tel que Henryk Sienkiewick le prolongera. S’y vérifie sa définition de l’histoire comme réflexion du présent sur le passé.Some scholars like Anne Green have shown that Flaubert in his historical novel, Salammbô, frequently alludes to contemporary history in spite of the obvious difference between the Carthaginian civilization and the modern world. In this essay I will try to grasp the shift in referenciality through a small description (a meeting between the wealthy, inspired by Aristotle’s Politics: Hugolian images of decadence from Les Châtiments appear superimposed on it, so that the archeological novel turns into an allegorical satire on the Second Empire.

Expression Surpassing Words: Gorecki’s Symphony No. 3, Op. 36 “Sorrowful Songs”

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Alyssa K. Griffith

2015-12-01

Full Text Available The experience of listening to Gorecki’s Symphony no. 3, op. 36 “Sorrowful Songs” is one that is not easily forgotten. It is not only musically captivating, but also historically fascinating. After its premiere in 1977, Gorecki’s piece captivated listeners across the globe as it became a cultural phenomenon in both Europe and America. The music was a stunning success in both the Classical and popular cultures. What is it about the music that is so captivating? How did the trending, popular thoughts compare to Gorecki’s original ideas and compositional motives? What actually inspired this piece? By looking at the composition and premise of each movement, I am going to introduce how the piece was written around the theme of maternal love and separation of mother and child. The Third Symphony was heavily influenced by Gorecki’s personal past, but also by his Catholic beliefs and by Polish history. The separate texts to this three movement piece deal individually with a mother’s lament over her son’s departure, the Virgin Mary’s grief at her Son’s death, and finally the words of an incarcerated prison girl to her mother. Because of the setting from which the third text was drawn, and because of Gorecki’s Polish history and experiences in the post-holocaust world, many people have interpreted this to be a “war piece” which avenges the sufferers of the Holocaust. According to Gorecki, this piece is a lament- it expresses a profound sense of grief which, arguably, cannot accurately be expressed with words. Gorecki used his music to confront, mourn, and express his pain and the pain of many other people. By finding primary sources, such as interviews of Henryk Gorecki, and by looking at the scholarly books and journals by Luke B. Howard, Adrian Thomas, and other scholars of Polish avant-garde music, I hope to properly understand and express the intentions Gorecki wished to convey by writing The Symphony of Sorrowful Songs.

Efficacy of radiosensitizing doped titania nanoparticles under hypoxia and preparation of an embolic microparticle

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Morrison RA

2017-05-01

Full Text Available Rachel A Morrison,1,* Malgorzata J Rybak-Smith,1,* James M Thompson,2 Bénédicte Thiebaut,3 Mark A Hill,2 Helen E Townley1,4 1Department of Engineering Science, 2Gray Laboratories, CRUK/MRC Oxford Institute for Radiation Oncology, University of Oxford, Oxford, 3Johnson Matthey, Technology Centre, Reading, Berkshire, 4Nuffield Department of Obstetrics and Gynaecology, John Radcliffe Hospital, University of Oxford, Oxford, UK *These authors have contributed equally to this work Abstract: The aim of this study was to develop a manufacturing protocol for large-scale production of doped titania radiosensitizing nanoparticles (NPs to establish their activity under hypoxia and to produce a multimodal radiosensitizing embolic particle for cancer treatment. We have previously shown that radiosensitizing NPs can be synthesized from titania doped with rare earth elements, especially gadolinium. To translate this technology to the clinic, a crucial step is to find a suitable, scalable, high-throughput method. Herein, we have described the use of flame spray pyrolysis (FSP to generate NPs from titanium and gadolinium precursors to produce titania NPs doped with 5 at% gadolinium. The NPs were fully characterized, and their capacity to act as radiosensitizers was confirmed by clonogenic assays. The integrity of the NPs in vitro was also ascertained due to the potentially adverse effects of free gadolinium in the body. The activity of the NPs was then studied under hypoxia since this is often a barrier to effective radiotherapy. In vitro radiosensitization experiments were performed with both the hypoxia mimetics deferoxamine and cobalt chloride and also under true hypoxia (oxygen concentration of 0.2%. It was shown that the radiosensitizing NPs were able to cause a significant increase in cell death even after irradiation under hypoxic conditions such as those found in tumors. Subsequently, the synthesized NPs were used to modify polystyrene embolization

Kinematografia niepamięci. Polskie filmy dokumentalne o Litzmannstadt Getto

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Ewa Ciszewska

2016-05-01

Dokumentarfilmen nicht auf. Jedoch  werden regelmäßig Fotografien verwendet, die von Walter Genewein, Mandel Gross und Henryk Ross zu Zeiten des Ghettos aufgenommen wurden.

Executive Summary - Our mission

International Nuclear Information System (INIS)

2005-01-01

On September 1 st 2003, the Henryk Niewodniczanski Institute of Nuclear Physics in Cracow joined the Polish Academy of Sciences. The Polish Academy of Sciences (PAN), founded in 1952, is a state-sponsored scientific institution acting through an elected corporation of leading scholars, their research organizations and through numerous scientific establishments. PAN is a major national scientific advisory body acting via its scientific committees which represent all disciplines of science. There are currently 79 PAN research establishments (institutes and research centers, research stations, botanical gardens and other research units) and a number of auxiliary scientific units (such as archives, libraries, museums, and PAN stations abroad). Our Institute is currently one of the largest research institutions of the Polish Academy of Sciences. The research activity of the Academy is financed mainly from the State budget via the Ministry of Scientific Research and Information Technology. The mission of the Institute of Nuclear Physics, IFJ is stated in its Charter. According to Paragraphs 5, 6, and 7 of the 2004 Charter, the Institute's duty is to carry out research activities in the following areas:1. High energy and elementary particle physics (including astrophysics), 2. Nuclear physics and physics of mechanisms of nuclear interaction, 3. Condensed matter physics, 4. Interdisciplinary research, and in particular: in radiation and environmental biology, environmental physics, medical physics, dosimetry, nuclear geophysics, radiochemistry and material engineering. The main tasks of the Institute are: 1. To perform research in the above disciplines, 2. To promote the development of scientists and of specialists qualified to carry out research in these disciplines, 3. To organize a Post-Doctoral Study Course, 4. To permit, through agreements with national and foreign research institutions, external scholars to train and gain academic qualifications in the Institute

Masseter muscle tension, chewing ability, and selected parameters of physical fitness in elderly care home residents in Lodz, Poland

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Gaszynska E

2014-07-01

Full Text Available Ewelina Gaszynska,1 Malgorzata Godala,2 Franciszek Szatko,1 Tomasz Gaszynski3 1Department of Hygiene and Health Promotion, Medical University of Lodz, Poland; 2Department of Nutrition and Epidemiology, Medical University of Lodz, Poland; 3Department of Emergency Medicine and Disaster Medicine, Medical University of Lodz, Poland Background: Maintaining good physical fitness and oral function in old age is an important element of good quality of life. Disability-related impairment of oral function contributes to a deterioration of the diet of older people and to the reduction of their social activity.Objectives: Investigate the association between masseter muscle tension, dental status, and physical fitness parameters.Materials and methods: Two hundred fifty-nine elderly care home residents (97 men, 162 women; mean age, 75.3±8.9 years were involved in this cross-sectional study. Their chewing ability was evaluated by masseter muscle tension palpation, differences of masseter muscle thickness, self-reported chewing ability, number of present and functional teeth, and number of posterior tooth pairs. Masseter muscle thickness was measured by ultrasonography. To assess physical fitness, hand grip strength and the timed up-and-go test were performed. Nutritional status was assessed using body mass index and body cell mass index (BCMI, calculated on the basis of electrical bioimpedance measurements. Medical records were used to collect information on systemic diseases and the number of prescribed medications. Subjects were also evaluated for their ability to perform ten activities of daily living.Results: Ninety-seven percent of the subjects suffered from systemic diseases. The three most prevalent illnesses were cardiac/circulatory 64.5%, musculoskeletal 37.3%, and endocrine/metabolic/nutritional 29.3%. Of the participants, 1.5% were underweight and more than one third (34.4% were overweight. Malnutrition (BCMI below normal was found in almost

Overview

International Nuclear Information System (INIS)

Budzanowski, A.

2002-01-01

successfully extracted beam from our AIC-144 cyclotron. The dosimeter calibration laboratory obtained formal accreditation. The Marian Miesowicz award of the Polish Academy of Arts and Sciences went to dr K. Golec-Biernat for his work on saturation effects in DIS at low Q 2 . Dr M. Kmiecik was awarded the Henryk Niewodniczanski prize for her outstanding work on transitions between various Jacobi shapes at high angular momentum rotation of 46 Ti nuclei. 534 papers of which 318 in journals listed by the Philadelphia Institute of Science Information were published at our Institute. The Institute hosted eight international and three national scientific conferences. We participated in one FW4 and seven FW5 UE programmes. We also completed a large renovation effort aimed at preparing new facilities at the main campus of the Institute for our high energy departments. Eleven scientists got their PhD degrees, five completed their habilitations and one got the title of a full professor. Two distinguished scientists were awarded the title of a Honorary Professor of the Henryk Niewodniczanski Institute of Nuclear Physics, namely Professor Bernard Haas (IRS, Strasbourg) and Professor Bernard Hyams (CERN). Last but not least, let me take this opportunity to extend my sincere thank-you to my colleagues and co-workers at the Institute for their great involvement and effort which helped us to achieve all the excellent results in 2001

Efficacy of Lactobacillus Reuteri DSM 17938 for the Treatment of Acute Gastroenteritis in Children: Protocol of a Randomized Controlled Trial.

Science.gov (United States)

Szymański, Henryk; Szajewska, Hania

2017-08-23

and is planned to be finalized in June 2018 for rotavirus nonvaccinated children. The recruitment of rotavirus-vaccinated children may be slower due to a relatively low coverage rate in Poland. Data analysis and submission to a peer-reviewed journal is expected within 3 months after completion of the study. This study will add to current knowledge on the efficacy of L reuteri DSM 17938 for the management of AGE. ClinicalTrials.gov NCT02989350; https://clinicaltrials.gov/ct2/show/NCT02989350 (Archived by WebCite at http://www.webcitation.org/6slOFkyTH). ©Henryk Szymański, Hania Szajewska. Originally published in JMIR Research Protocols (http://www.researchprotocols.org), 23.08.2017.

Executive Summary - Our mission

International Nuclear Information System (INIS)

2007-01-01

Full text: The Henryk Niewodniczanski Institute of Nuclear Physics (Instytut Fizyki Jadrowej im. Henryka Niewodniczanskiego, IFJ PAN) is currently the largest research institution of the Polish Academy of Sciences (Polska Akademia Nauk). The research activity of the Academy is financed mainly from the State budget via the Ministry of Science and Higher Education. The mission of IFJ PAN is stated in its Charter. According to Paragraphs 5, 6, and 7 of the 2004 Charter, the Institute's duty is to carry out research activities in the following areas: 1. High energy and elementary particle physics (including astrophysics), 2. Nuclear physics and strong interaction, 3. Condensed matter physics, 4. Interdisciplinary research, in particular: in radiation and environmental biology, environmental physics, medical physics, dosimetry, nuclear geophysics, radiochemistry and material engineering. The main tasks of the Institute are: 1. To perform research in the above disciplines, 2. To promote the development of scientists and of specialists qualified to carry out research in these disciplines, 3. To organize a Post-Graduate Study Course, 4. To permit, through agreements with national and foreign research institutions, external scholars to train and gain academic qualifications in the Institute's laboratories, 5. To collaborate with national and local authorities in providing them with expertise in the Institute's research topics, especially concerning radiation protection. These tasks are fulfilled by: 1. Performing individual and coordinated research through individual and collective research grant projects, 2. Initiating and maintaining cooperation with laboratories, organizations and institutions performing similar activities, in Poland and abroad, 3. Conferring scientific degrees and titles, 4. Distributing research results obtained, through peer-reviewed publications and other public media, 5. Organizing scientific meetings, conferences, symposia, training workshops, etc

Department of Nuclear Reaction - Overview

International Nuclear Information System (INIS)

Budzanowski, A.

2001-01-01

asymmetry. The same effects can be crucial for the extraction of polarized quark distributions (spin puzzle) from semi-inclusive production of pions in DIS. It was carefully studied how production of dijets in real and virtual photoproduction provides new information on unintegrated gluon distribution. We have completed the construction of the Forward Wall detector for the CHICSi experiment at the Celsius synchrotron. First tests with 20 Ne beam at 200 MeV/nucleon on 40 Ar and 14 N targets were performed. New results on the formation of dtμ, Muonic Molecule in Solid Hydrogen Target were obtained. First tests of the low energy spallation apparatus for measuring low energy spallation products emitted in proton induced reactions were performed using accelerator facilities at Catania (Italy). Further studies of statistical aspects of nuclear coupling to continuum were pursued. It was found that in the region of higher density of states the coupling to continuum is consistent with the statistical model. One Ph.D. thesis was completed under the supervision of Prof. Drozdz. The newly born doctor J. Kwapien was awarded The Henryk Niewodniczanski prize for his scientific achievement in studying the brain function. (author)

Overview

International Nuclear Information System (INIS)

Budzanowski, A.

2002-01-01

. The value of the baryonic chemical potential consistently decreases down to the value of μ B = 29 MeV at the collision energy √s NN = 200 GeV for the Au + Au system. The time scale of the thermal multifragmentation of 197 Au nuclei induced by a fast proton of the energy of 8.1 GeV was established. It was proved that it is a fast process, with characteristic decay time τ of the order of 10 -22 s. The first observation of the Jacobi shape transition accompanying the fast rotation of the 46 Ti nucleus was made. For the first time, non-hem iron was found in the low - spin state of Fe 2+ which indicates that NHFe initiates the cyclic transport of electrons in photosystem II. The result was published in Applied Organometallic Chemistry. The medium T-matrix theory was developed for superfluid nuclear matter. This new theoretical achievement was published in Phys. Rev. C. Using the ''ab initio'' method for structure calculation of the FeBO 3 compound, a special phase transition with spatial group symmetry unchanged, was found for the metal - isolator and magnetic - nonmagnetic cases. The advantage of the ''ab initio'' method is that the phase transition can be studied in the region of pressure values often difficult to access experimentally. A high level of the concentration of Pu and Am was found in sculls of prehistoric fossil animals. Legal accreditation for measuring individual radiation doses was granted to our second laboratory. Together with the laboratory for scaling and legalizing portable dosimeters, it should resume public services in 2003, hopefully providing some additional income for the Institute. Two doctors obtained their habilitation degrees, and three Associate Professors became full Professors. A group of laboratories from different departments formed a Centre of Excellence in the field of the Quality of Life, which was approved by the European Union. This may help us to obtain additional money for research as well. The Henryk Niewodniczanski prize was

Executive Summary - Historical background

International Nuclear Information System (INIS)

2005-01-01

The Institute of Nuclear Physics (INP) was established in Cracow in 1955. The post-war excitement of engaging in scientific activity, can certainly be credited to the talent, experience and unusual personality of Professor Henryk Niewodniczanski, the founder and first Director of the INP. In the 60's the INP research activity was concentrated around the Russian U120 Cyclotron, built in 1958 which provided deuteron beams up to 14.5 MeV and of alpha particles up to 29 MeV. A small 48 cm pole-piece cyclotron with was in-house constructed, and used for PIXE analyses and RBA material studies. In 1960's, the nuclear spectroscopy group began building several types of magnetic beta ray spectrometers to study excited levels of neutron-deficient isotopes provided by the 660 MeV cyclotron of the JINR. In parallel, studies of spin polarization of n and p emitted in the deuteron stripping reaction were performed. Studies of condensed matter using pulsed neutron beams from the IBR30 and Kjeller (Norway) reactors had also began. The NMR signal was first observed in Poland by physicists from the Jagiellonian University, and a well equipped NMR Laboratory was also created at the INP. A small theoretical physics department was established to support experimental research. Applied physics, based on the research performed in the INP was also developed. Following the interest in fast neutron radiotherapy, initiated by the Gray Laboratory in Hammersmith, a beam of fast neutrons was produced on a Be target by 13.5 MeV deuterons from the U120 and applied for cancer therapy, in a collaborative effort with the Centre of Oncology in Cracow. Over a period of 10 years, some 500 patients were treated, in selected types of salivary gland cancer and post-mastectomy recurrences. In the late 60's a technology of thermoluminescent dosimeters (TLD) was developed at the INP, based on specially activated LiF. The method was patented and TLDs, manufactured at the INP, are nowadays applied by in over 30

The churches dedicated to Saint Bishop and Martyr Stanisław in Kraków, built in 20th century

Directory of Open Access Journals (Sweden)

Józef Szymon Wroński

2003-12-01

Full Text Available 1. Die Pfarrkirche Zum Hl Bischof und Märtyrer Stanislaus in Dąbie Dąbie liegt 3 Kilometer östlich vom Stadtzentrum entfernt. In die Stadt wurde es 1911 eingemeindet. In den Jahren 1965-75 entstand hier eine Wohnsiedlung. In den nächsten Jahren -infolge der zunehmenden Einwohnerzahl - erfolgte eine Verdichtung der Wohnsiedlungsbebauung. Das Grundstück, auf dem die Kirche steht, liegt im Winkel zwischen der Weichsel und der Białucha, im Bereich der ehemaligen österreichischen Schanze FS-16. Es war stark mit Bäumen bepflanzt. Das bereitete aber viele Schwierigkeiten, d.h. es gab Probleme sowohl mit der Ausdünnung der Bäume, als auch mit der Erhaltung des restlichen Baumbestandes. Am 11. März 1982 erhielt Dąbie endlich eine Baugenehmigung für den Bau einer Kirche in der Wohnsiedlung. Die Kirche, die nach einem Projekt des Architekten Henryk Kamiński in den Jahren 1984-2000 errichtet wurde, ist der Gemeinde zur Verfügung gestellt, aber im Innern noch nicht ausgestattet. Der Bau der Kirche zerfällt in zwei Phasen: die erste Phase dauerte bis zum Jahre 1989, in dem es zu einem Probstwechsel kam. Der neue Probst und zugleich der Investor Wiesław Macuda übernahm den Bau in dem Moment, als die Mauern der Kirche bis zu den Sohlbänken ausgeführt waren. Mit voller Energie ging er ans Werk, um den Bau weiterzuführen. Die Kirche hat zwei Geschosse: - die sog. Unterkirche im Erdgeschoss und die Oberkirche. Die Kirche hat einen fast quadratischen Grundriss, der diagonal gestellt und stark modifiziert ist. Die eigentliche Kirche - die Oberkirche ist dreischiffig. Die Seitenschiffe sind von dem Mittelschiff durch (je einen Pfeiler getrennt. Das Mittelschiff hat einen Obergaden (Region der Fenster im Mittelschiff iner Basilika in der Form einer Lichtnische, durch die das Licht in den Raum hineinfällt und die ganze Kirche mit Licht überflutet ist. Von hier aus streben die „Scheiben-wände” der Obergadenlichtnische nach oben. Ziel ist die