Grand Mal Seizure

Science.gov (United States)

... grand mal seizures include: A family history of seizure disorders Any injury to the brain from trauma, a ... the risk of birth defects. If you have epilepsy and plan to become pregnant, work with your ...

Knowing and praxis

DEFF Research Database (Denmark)

Axel, Erik

2005-01-01

This paper explores the interconnectedness of knowledge and praxis in a concrete context. It argues that, and demonstrates how, knowledge is connected to its context and changes with context. A preconception of this point was used and developed further in a participatory observation in the contro...

Consentimiento informado: una praxis dialogica para la investigacion

Science.gov (United States)

Mondragon-Barrios, Liliana

2009-01-01

El consentimiento informado es un proceso, en el que una persona acepta participar en una investigation, conociendo los riesgos, beneficios, consecuencias o problemas que se puedan presenter durante el desarrollo de la misma. El objetivo de este trabajo es reunir las caracteristicas del proceso de consentimiento informado (PCI) pare que su discernimiento y cumplimiento posibilite el ejercicio etc° dialogico, reflexivo y responsable del investigador. Se presentan los resultados de una extensa revision de les elementos del PCI, desde sus cornponentes hasta su fundamento etico y legal, incluyendo los mites y realidades que existen sobre el formato de consentimiento informado come recurso legal de protection. El consentimiento informado no es un formato establecido que los investigadores repliquen, se trata de que la praxis del PCI sea una tarea cotidiana dentro de la investigation con seres humanos, como comunicaciOn deliberative y critica, responsable y comprometida entre dos agentes morales, investigador-investigado. PMID:19507477

Mal de terre

CERN Document Server

Reeves, Hubert

2003-01-01

Notre planète va mal: réchauffement climatique, épuisement des ressources naturelles, pollutions des sols et de l'eau provoquées par les industries civiles et guerrières, disparité des richesses, malnutrition des hommes, taux d'extinction effarant des espèces vivantes, etc.

From theory to praxis

DEFF Research Database (Denmark)

Ejersbo, Lisser Rye; Misfeldt, Morten

2017-01-01

This article is a description and discussion of a design research project in which we introduced a research idea about the influence of language on number concepts development into praxis on a school in grades K-3. Danish children have difficulties remembering the Danish number names because the ...

Praxis y confianza

OpenAIRE

Arias-Castañeda, Eduardo

2001-01-01

Para hacer real la tarea filosófica de orientar la actividad humana, y enriquecer los procesos formativos y educativos, se aborda el tema de la confianza desde la perspectiva del análisis de la praxis de Antonio González. Se incluye la reproducción en blanco y negro de una obra del artista plástico Rubén Méndez.

Gupta, Dr Chhitar Mal

Indian Academy of Sciences (India)

Gupta, Dr Chhitar Mal Ph.D. (Agra), FNA, FNASc, FAMS, FTWAS Council Service: 1998-2000. Date of birth: 1 September 1944. Specialization: Membrane Biology, Bio-organic Chemistry and Molecular Biophysics Address: Distinguished Professor and Infosys Chair, Institute of Bioinformatics & Applied Biotechnology, Room ...

El mal de ojo en Toledo

OpenAIRE

Salvador Hernández, Pedro Pablo

2017-01-01

La presente tesis doctoral estudia el fenómeno del Mal de Ojo en la provincia de Toledo desde una perspectiva antropológica. El trabajo se estructura en tres partes. Por un lado, se analiza el marco general de la antropología médica, la medicina popular, el curanderismo y los síndromes culturales. Por otro lado, se aborda el fenómeno del Mal de Ojo, analizando los síntomas, la etiología, el tratamiento y la prevención de esta enfermedad cultural. La tercera parte recoge cuatro estudios de cas...

[Clonage of the "malA" region of "Escherichia coli" K12: nucleotide sequence of the regulatory region and the promoters, identification and purification of the MalT-activator protein (author's transl)].

Science.gov (United States)

Raibaud, O; Débarbouillé, M; Cossart, P

1982-01-01

A 5,800-bp (base pair) HindIII-EcoRI DNA fragment containing malT, the positive regulator gene of the maltose regulon, and most of malP, the structural gene for maltodextrin phosphorylase, was cloned into pBR322. A sequence of 802 bp was established in a DNA segment containing the promotor for malPQ and the promoter for malT. A total of 611 bp separates the initiation codons for these two genes, which are transcribed in opposite directions. The malT product was identified as a 94,000 dalton polypeptide.

Exploring graduate teachers' perceptions of their praxis after an AELS course

Directory of Open Access Journals (Sweden)

Arnold, Laura Jane

2015-12-01

Full Text Available While speakers of English as an additional language are more common than native English speakers, most English teachers do not know how to teach plurilingual learners in their classrooms. Though studies have looked at the effect of teacher education on praxis, there is a dearth of studies in South Africa that have examined teachers’ perceptions of their praxis after a course on bilingual education models and practices. This study investigates whether in-service teachers feel that the ‘Paradigms and Methods in Applied English Language Studies’ course helped them to further develop their praxis. Students’ weekly reflection pieces were examined for evidence of critical reflection before interviews were conducted with three students who have taught, or are currently teaching in under-resourced areas. All participants reported that they had developed a more bilingual teaching praxis, but they often felt unsure of how to practically implement their learning from the course. Based on this finding two recommendations to lecturers and course coordinators of AELS courses are provided. Teacher praxis could be strengthened by 1 referring students to articles on bilingual education models and practices that mirror their teaching contexts and 2 explicitly teaching students how to reflect on implementing the theories that they have learned during the course within their classrooms.

Mucin 1 (MUC1 is a novel partner for MAL2 in breast carcinoma cells

Directory of Open Access Journals (Sweden)

McGuckin Michael A

2009-01-01

Full Text Available Abstract Background The MAL2 gene, encoding a four-transmembrane protein of the MAL family, is amplified and overexpressed in breast and other cancers, yet the significance of this is unknown. MAL-like proteins have trafficking functions, but their molecular roles are largely obscure, partly due to a lack of known binding partners. Methods Yeast two-hybrid screening of a breast carcinoma cDNA expression library was performed using a full-length MAL2 bait, and subsequent deletion mapping experiments were performed. MAL2 interactions were confirmed by co-immunoprecipitation analyses and confocal microscopy was employed to compare protein sub-cellular distributions. Sucrose density gradient centrifugation of membranes extracted in cold Triton X-100 was employed to compare protein distributions between Triton X-100-soluble and -insoluble fractions. Results The tumor-associated protein mucin 1 (MUC1 was identified as a potential MAL2 partner, with MAL2/MUC1 interactions being confirmed in myc-tagged MAL2-expressing MCF-10A cells using co-immunoprecipitation assays. Deletion mapping experiments demonstrated a requirement for the first MAL2 transmembrane domain for MUC1 binding, whereas the MAL2 N-terminal domain was required to bind D52-like proteins. Confocal microscopy identified cytoplasmic co-localisation of MUC1 and MAL2 in breast cell lines, and centrifugation of cell lysates to equilibrium in sucrose density gradients demonstrated that MAL2 and MUC1 proteins were co-distributed between Triton X-100-soluble and -insoluble fractions. However co-immunoprecipitation analyses detected MAL2/MUC1 interactions in Triton X-100-soluble fractions only. Myc-MAL2 expression in MCF-10A cells was associated with both increased MUC1 detection within Triton X-100-soluble and -insoluble fractions, and increased MUC1 detection at the cell surface. Conclusion These results identify MUC1 as a novel MAL2 partner, and suggest a role for MAL2 in regulating MUC1

To Leave a Praxis to Itself May Be to Upset It in Unintended Ways

DEFF Research Database (Denmark)

Olsen, Poul Bitsch; Axel, Erik

by the researchers on a conception of situated praxis, of conflictual cooperation, and on an interest in morals and the meaning of upsetting practices. The organization of the material may hopefully provoke discussions around praxis as part of its further development. Thus, our presentation is based on a notion...... of praxis. Praxis is formed by the reciprocal differentiations of acts. In order to be able to act here, we try to arrange things to be done in specific ways there. In order to build the house here, we arrange a supply of inhabitants here, a conglomerate of producers there etc.. Furthermore, what we achieve...

Evidence for tension-based regulation of Drosophila MAL and SRF during invasive cell migration.

Science.gov (United States)

Somogyi, Kálmán; Rørth, Pernille

2004-07-01

Cells migrating through a tissue exert force via their cytoskeleton and are themselves subject to tension, but the effects of physical forces on cell behavior in vivo are poorly understood. Border cell migration during Drosophila oogenesis is a useful model for invasive cell movement. We report that this migration requires the activity of the transcriptional factor serum response factor (SRF) and its cofactor MAL-D and present evidence that nuclear accumulation of MAL-D is induced by cell stretching. Border cells that cannot migrate lack nuclear MAL-D but can accumulate it if they are pulled by other migrating cells. Like mammalian MAL, MAL-D also responds to activated Diaphanous, which affects actin dynamics. MAL-D/SRF activity is required to build a robust actin cytoskeleton in the migrating cells; mutant cells break apart when initiating migration. Thus, tension-induced MAL-D activity may provide a feedback mechanism for enhancing cytoskeletal strength during invasive migration.

Modelling of innovative SANEX process mal-operations

International Nuclear Information System (INIS)

McLachlan, F.; Taylor, R.; Whittaker, D.; Woodhead, D.; Geist, A.

2016-01-01

The innovative (i-) SANEX process for the separation of minor actinides from PUREX highly active raffinate is expected to employ a solvent phase comprising 0.2 M TODGA with 5 v/v% 1-octanol in an inert diluent. An initial extract / scrub section would be used to extract trivalent actinides and lanthanides from the feed whilst leaving other fission products in the aqueous phase, before the loaded solvent is contacted with a low acidity aqueous phase containing a sulphonated bis-triazinyl pyridine ligand (BTP) to effect a selective strip of the actinides, so yielding separate actinide (An) and lanthanide (Ln) product streams. This process has been demonstrated in lab scale trials at Juelich (FZJ). The SACSESS (Safety of Actinide Separation processes) project is focused on the evaluation and improvement of the safety of such future systems. A key element of this is the development of an understanding of the response of a process to upsets (mal-operations). It is only practical to study a small subset of possible mal-operations experimentally and consideration of the majority of mal-operations entails the use of a validated dynamic model of the process. Distribution algorithms for HNO_3, Am, Cm and the lanthanides have been developed and incorporated into a dynamic flowsheet model that has, so far, been configured to correspond to the extract-scrub section of the i-SANEX flowsheet trial undertaken at FZJ in 2013. Comparison is made between the steady state model results and experimental results. Results from modelling of low acidity and high temperature mal-operations are presented. (authors)

Open Praxis vol. 8 issue 4

Directory of Open Access Journals (Sweden)

Inés Gil-Jaurena (ed., Various authors

2016-12-01

Full Text Available This last Open Praxis issue in 2016 is an open issue that includes four research papers, two innovative practice papers and two book reviews. It also includes the list of reviewers that have collaborated in volume 8.

Estados de mal epiléptico na sindrome Delennox-Gastaut: aspectos terapeuticos

Directory of Open Access Journals (Sweden)

José Geraldo Speciali

1977-09-01

Full Text Available Foram descritas as condutas terapêuticas utilizadas nos estados de mal epiléptico, convulsivos e não convulsivos, observados em 14 pacientes com síndrome de Lennox-Gastaut. Verificou-se relação temporal entre aparecimento de estado de mal epiléptico e início de tratamento com clonazepam e difenilhidantoina; a retirada dessas medicações foi seguida pelo desaparecimento dos estados de mal. Indicou-se a possibilidade de tratamento dos estados de mal epiléptico modificando-se o esquema terapêutico administrado por via oral, reservando-se o tratamento parenteral para os estados com comprometimento progressivo da consciência e/ou dos distúrbios neurovegetativos.

A Multicultural Education Praxis: Integrating Past and Present, Living Theories, and Practice

Science.gov (United States)

Shannon-Baker, Peggy

2018-01-01

In our current climate of heightened conservatism and criticism, multicultural education is as important as ever. This article argues for the need to reframe multicultural education as a praxis based on its social justice-oriented principles, values, and practices. Using practitioner action research, I examine my implementation of such a praxis in…

El Gobierno del mal menor

DEFF Research Database (Denmark)

Agustin, Oscar Garcia

2012-01-01

El Gobierno no aspira a ser bueno ni malo. Se conforma con ser el Gobierno del mal menor, cuyas medidas drásticas y poco populares están destinadas a salvar a los ciudadanos del desastre que no ha llegado todavía pero podría llegar....

Impact of Enquiry Based Learning (EBL) on student midwife praxis.

Science.gov (United States)

Byrne, Anita; McNeill, Jennifer; Rogers, Katherine; Porter, Sam

2018-03-01

Midwifery training in Ireland moved to Higher Education in 2006. This shift established a physical and educational separation of theory and practice. The adoption of Enquiry Based Learning (EBL) by one Irish midwifery education institution attempted to address this division. Enquiry Based Learning (EBL) has the potential to develop student reflexivity and evidence assimilation across the career-span and may therefore enhance student praxis. EBL has been championed as an example of an educational model that supports praxis, helping to create competent practitioners through the use of authentic learning scenarios that address the theory practice divide. The current research study represents the first formal evaluation of EBL in undergraduate midwifery education in the South of Ireland. The study was a mixed-methods design that utilised focus groups, interviews and survey to ascertain the opinions of first exposure to EBL amongst a cohort of first year student midwives. Findings demonstrate the value of EBL in enhancing student midwife praxis. Copyright © 2018 Elsevier Ltd. All rights reserved.

Epigenetic silencing of MAL, a putative tumor suppressor gene, can contribute to human epithelium cell carcinoma

Directory of Open Access Journals (Sweden)

Zhang Jun

2010-11-01

Full Text Available Abstract Background To identify new and useful candidate biomarkers in head and neck squamous cell carcinoma (HNSCC, we performed a genome-wide survey and found that Myelin and lymphocyte-associated protein (MAL was a gene that was markedly down-regulated in HNSCC. Hence, we investigated the mechanism of MAL silencing and the effects of MAL on the proliferation, invasion, and apoptotic potential in HNSCC. Results MAL was significantly down-regulated in 91.7% of HNSCC specimens at the mRNA level as compared with adjacent normal tissues (P = 0.0004. Moreover, the relative transcript levels of the MAL gene were remarkably decreased by five-fold in nine HNSCC cell lines as compared with normal head and neck epithelium cells. MAL gene expression was restored in 44%, 67%, and 89% in HNSCC cell lines treated with TSA, 5-Aza-dC, and TSA plus 5-Aza-dC, respectively. Furthermore, bisulfate-treated DNA sequencing demonstrated that the two CpG islands (that is, M1 and M2 located in MAL promoter region were completely methylated in the HNSCC cell lines (CpG methylated ratio was more than 90%, and only one CpG island (that is, M1 was partially methylated in HNSCC tissues (CpG methylated ratio between 20% and 90%. A significant reduction in cell proliferation and a change in the cell cycle profile were also observed in MAL transfectants. Matrigel assay demonstrated that the invasiveness of HNSCC cells significantly decreased. A significant increase in the population of apoptotic cells was observed in MAL transfected cells. The exogenous expression of the MAL gene suppressed malignant phenotypes, while the cell death induced by MAL gene transfer was a result of apoptosis as demonstrated by the induction of cleavage of the poly (that is, ADP-ribose polymerase. Additionally, tumor growth was suppressed in cells expressing MAL as compared with cells not expressing MAL. Conclusion Our data suggest that the epigenetic inactivation of MAL, as a candidate tumor

Analysis of refrigerant mal-distribution

DEFF Research Database (Denmark)

Kærn, Martin Ryhl; Elmegaard, Brian

2009-01-01

to be two straight tubes. The refrigerant maldistribution is then induced to the evaporator by varying the vapor quality at the inlet to each tube and the air-flow across each tube. Finally it is shown that mal-distribution can be compensated by an intelligent distributor, that ensures equal superheat...

Assessment of allelic diversity in intron-containing Mal d 1 genes and their association to apple allergenicity

Directory of Open Access Journals (Sweden)

Bolhaar Suzanne THP

2008-11-01

Full Text Available Abstract Background Mal d 1 is a major apple allergen causing food allergic symptoms of the oral allergy syndrome (OAS in birch-pollen sensitised patients. The Mal d 1 gene family is known to have at least 7 intron-containing and 11 intronless members that have been mapped in clusters on three linkage groups. In this study, the allelic diversity of the seven intron-containing Mal d 1 genes was assessed among a set of apple cultivars by sequencing or indirectly through pedigree genotyping. Protein variant constitutions were subsequently compared with Skin Prick Test (SPT responses to study the association of deduced protein variants with allergenicity in a set of 14 cultivars. Results From the seven intron-containing Mal d 1 genes investigated, Mal d 1.01 and Mal d 1.02 were highly conserved, as nine out of ten cultivars coded for the same protein variant, while only one cultivar coded for a second variant. Mal d 1.04, Mal d 1.05 and Mal d 1.06 A, B and C were more variable, coding for three to six different protein variants. Comparison of Mal d 1 allelic composition between the high-allergenic cultivar Golden Delicious and the low-allergenic cultivars Santana and Priscilla, which are linked in pedigree, showed an association between the protein variants coded by the Mal d 1.04 and -1.06A genes (both located on linkage group 16 with allergenicity. This association was confirmed in 10 other cultivars. In addition, Mal d 1.06A allele dosage effects associated with the degree of allergenicity based on prick to prick testing. Conversely, no associations were observed for the protein variants coded by the Mal d 1.01 (on linkage group 13, -1.02, -1.06B, -1.06C genes (all on linkage group 16, nor by the Mal d 1.05 gene (on linkage group 6. Conclusion Protein variant compositions of Mal d 1.04 and -1.06A and, in case of Mal d 1.06A, allele doses are associated with the differences in allergenicity among fourteen apple cultivars. This information

Maltose-binding protein effectively stabilizes the partially closed conformation of the ATP-binding cassette transporter MalFGK2

KAUST Repository

Weng, Jingwei; Gu, Shuo; Gao, Xin; Huang, Xuhui; Wang, Wenning

2017-01-01

Maltose transporter MalFGK2 is a type-I importer in the ATP-binding cassette (ABC) transporter superfamily. Upon the binding of its periplasmic binding protein, MalE, the ATPase activity of MalFGK2 can be greatly enhanced. Crystal structures of the MalFGK2-MalE-maltose complex in a so-called

Maltose-binding protein effectively stabilizes the partially closed conformation of the ATP-binding cassette transporter MalFGK2

KAUST Repository

Weng, Jingwei

2017-02-23

Maltose transporter MalFGK2 is a type-I importer in the ATP-binding cassette (ABC) transporter superfamily. Upon the binding of its periplasmic binding protein, MalE, the ATPase activity of MalFGK2 can be greatly enhanced. Crystal structures of the MalFGK2-MalE-maltose complex in a so-called

Kewenangan Baitul Mal Aceh dalam Pendistribusian Zakat

Directory of Open Access Journals (Sweden)

Surya Darma

2017-08-01

ABSTRACT: Aceh is a province in Indonesia that is granted a special authority to govern and manage its own government affairs. One of them is zakat as one of the original source of income. Baitul Mal institution is established by qanun (local law to manage the zakat fund. In regard with its management procedure as the original revenue of the area, which is managed by Baitul Mal, is regulated in qanun and governor regulation. Its expenditure or distribution is in accordance with the guidance of the Islamic Sharia, that is, it may only be the part specified in the Qur'an, not for others. One of the forms of its distributions’ forms is the provision of vocational capital to productive zakat recipients through Productive Zakat Management Units. It is done in the form of interest-free loans. It is slightly different, as the zakat must be divided in full without needing to be returned. Although its interest-free loan is legal, it requires further explanation to avoid negative views. The finding shows that in 2013, 2014 and 2015, Baitul Mal Aceh, gains its funds more than expected. It requires careful handling in order to avoid  any problems in the future.

BAYT AL-MAL AND ITS ROLE IN ECONOMIC DEVELOPMENT: A CONTEMPORARY STUDY

Directory of Open Access Journals (Sweden)

Md. Habibur RAHMAN

2015-08-01

Full Text Available Bayt al-Mal, known as the public treasury of Islamic state, was established by the Prophet-may peace be upon Him- and then it was further extended and expanded by Abu Bakr and Umar, who succeeded the Prophet as the Caliph of the Islamic state. It is the state treasury that keeps the sole authority to mobilize the funds of the state. This paper aims to study the potential role and contribution of Bayt al-Mal to economic development in the contemporary context. It will be a qualitative paper and the analytical and descriptive method will be applied. Historically Bayt al-Mal played a great role in the distribution and redistribution of funds. It performed the function that is similar to the function of the ministry of finance at present. It also carried out the jobs of central bank in terms of monitoring, issuing currencies, controlling credits and so forth. Through discussing its sources and expenditures the paper posits that the role of Bayt al-Mal can be revived and accelerated by, for example, providing small-medium funds, managing Zakah and awqaf, channeling the funds, issuing various financial instruments and so forth. Bayt al-Mal could have a significant role in the eradication of poverty from the state. The paper concludes that with the rapid growth of Islamic finance, the Bayt al-Mal can be utilized in parallel in order to have a robust economic development.

Social justice praxis in education: Towards sustainable ...

African Journals Online (AJOL)

Lastly, these practitioners aligned their management strategies with human rights values, as well as human dignity and equality, and their strategies found pride of place in extant ubuntu principles. Keywords: determinants; education; human rights; management strategies; restorative; social justice praxis; sustainable ...

Meaningful Academic Work as Praxis in Emergence

Directory of Open Access Journals (Sweden)

Keijo Räsänen

2008-01-01

Full Text Available The managerial form of university governance has changed the conditions of academic work in many countries. While some academics consider this a welcome development, others experience it as a threat to their autonomy and to the meaningfulness of their work. This essay suggests a stance in response to the current conditions that should serve especially the latter group of academics. The claim is that by approaching academic work as a potential praxis in emergence, it is possible to appreciate local, autonomous activity in renewing academic work. Even if such efforts remain difficult, dispersed in space, discontinuous in time, and incomplete, they may provide a sense of direction and keep up hope. The conception of praxis is a way of articulating the mission of such efforts; simultaneously, it is also a way of defining an epistemic object for research on academic work.

Estado de mal epiléptico en pediatría

Directory of Open Access Journals (Sweden)

Jorge Malagón Valdez

2013-09-01

Full Text Available El estado de mal epiléptico es una emergencia médica en la cual se presentan crisis epilépticas por 30 minutos o más de actividad continua, o bien dos o más crisis consecutivas sin recuperación completa de la conciencia entre las mismas. Actualmente se considera que una crisis epiléptica convulsiva o no, que dure más de 5 minuto se deberá considerar un estado de mal epiléptico. Se han utilizado diversos fármacos para el tratamiento de esta patología y sus secuelas. Hay un consenso generalizado en que se debe realizar un manejo agresivo para disminuir su morbi-mortalidad, sin olvidarse que la causa del estado de mal es importante para su manejo, control y sus secuelas.

Religion and covenantal praxis in first century Judeanism

African Journals Online (AJOL)

p1243322

This article indicates how the two cultural features of religion and covenantal praxis .... and the home, introduced Judeans into a world where religion and covenantal ... states that Judeans from Mesopotamia made “dedicatory offerings” to the.

Open Praxis, volume 9 issue 2

Directory of Open Access Journals (Sweden)

Inés Gil-Jaurena (ed., various authors

2017-06-01

Full Text Available For a fourth consecutive year Open Praxis has partnered with the Open Education Consortium for the publication of selected papers among those presented in the 2017 Open Education Global Conference (Cape Town, South Africa, 8-10 March, 2017. After the peer-review process 7 papers were accepted for publication. Additionaly, this issue includes 3 innovative practice papers.

Automethodology: Tracing a Home for Praxis-Oriented Ethnography

Directory of Open Access Journals (Sweden)

Sandra L. Pensoneau-Conway

2011-12-01

Full Text Available The authors trace the development of ethnographic practices according to the methodological assumptions of ethnographers within different historical periods. As communication scholars, the authors find Calvin O. Schrag's conceptualization of the self to be informative and advantageous for navigating an ethnographic sense of ‘self in the current status of the methodological contestation. Borrowing from Schrag’ s work, which focuses on communicative praxis in understanding the self, this article explores an innovative methodological framework called automethodology. By examining the deployment and emplotment of the self within the automethods of autobiography, autoethnography, narrative co-construction, community autoethnography, critical complete-member ethnography, reflexive ethnography, autoperformance, and layered account, the authors develop epistemological foundations for praxis-oriented ethnographers. Throughout this journey, the authors end up situating themselves in a place they consider home-in the practices of automethodology.

Maltase protein of Ogataea (Hansenula) polymorpha is a counterpart to resurrected ancestor protein ancMALS of yeast maltases and isomaltases

DEFF Research Database (Denmark)

Viigand, Katrin; Visnapuu, Triinu; Mardo, Karin

2016-01-01

and mutation of the genes. We studied substrate specificity of the maltase protein MAL1 from an earlier diverged yeast, Ogataea polymorpha (Op), in the light of this hypothesis. MAL1 has extended substrate specificity and its properties are strikingly similar to those of resurrected ancMALS. Moreover, amino......, indicating the power of the method to predict substrate binding. Deletion of either the maltase (MAL1) or α-glucoside permease (MAL2) gene in Op abolished the growth of yeast on MAL1 substrates, confirming the requirement of both proteins for usage of these sugars....

Religion and covenantal praxis in first century Judeanism

African Journals Online (AJOL)

p1243322

long term. Indeed, religion and covenantal praxis combined to make Judeanism a ..... The meat was to be eaten in the Temple, on the same day, sharing it ...... for consumption from “impure” food that was disallowed (Lv 11:1-23; Dt 14:3-. 21).

Characterization of different crystal forms of the alpha-glucosidase MalA from Sulfolobus solfataricus

DEFF Research Database (Denmark)

Ernst, Heidi Asschenfeldt; Willemoës, Martin; Lo Leggio, Leila

2005-01-01

MalA is an alpha-glucosidase from the hyperthermophilic archaeon Sulfolobus solfataricus. It belongs to glycoside hydrolase family 31, which includes several medically interesting alpha-glucosidases. MalA and its selenomethionine derivative have been overproduced in Escherichia coli...

Tackling racism as a "wicked" public health problem: Enabling allies in anti-racism praxis.

Science.gov (United States)

Came, Heather; Griffith, Derek

2018-02-01

Racism is a "wicked" public health problem that fuels systemic health inequities between population groups in New Zealand, the United States and elsewhere. While literature has examined racism and its effects on health, the work describing how to intervene to address racism in public health is less developed. While the notion of raising awareness of racism through socio-political education is not new, given the way racism has morphed into new narratives in health institutional settings, it has become critical to support allies to make informing efforts to address racism as a fundamental cause of health inequities. In this paper, we make the case for anti-racism praxis as a tool to address inequities in public health, and focus on describing an anti-racism praxis framework to inform the training and support of allies. The limited work on anti-racism rarely articulates the unique challenges or needs of allies or targets of racism, but we seek to help fill that gap. Our anti-racism praxis for allies includes five core elements: reflexive relational praxis, structural power analysis, socio-political education, monitoring and evaluation and systems change approaches. We recognize that racism is a modifiable determinant of health and racial inequities can be eliminated with the necessary political will and a planned system change approach. Anti-racism praxis provides the tools to examine the interconnection and interdependence of cultural and institutional factors as a foundation for examining where and how to intervene to address racism. Copyright © 2017 Elsevier Ltd. All rights reserved.

Historia de la voluntad y banalidad del mal

Directory of Open Access Journals (Sweden)

Prior Olmos, Ángel

2010-04-01

Full Text Available This article discusses the connections existing in The Life of the Mind between the theory of the banality of evil and the history of the will. It interprets Eichmann in Jerusalem as a work about bureaucratic evil, but above all as research concerning both moral and juridical responsibility. From the history of the will it highlights three different aspects that can be connected with the problem of responsibility: the ontology of contingency, the idea of individuality linked to the will and the capacity of transcendence and resistance that we see in the Duns Scotus’ theory, where liberty equals indifference. Finally, it suggests a link between the banality of evil and the ontology of good as these are present in “Some questions of moral philosophy” (1965-1966, the fight against Gnosticism and the defense of a relationship between morality and evil’s intelligibility.

El artículo plantea las conexiones entre la tesis de la banalidad del mal y la historia de la voluntad presente en La vida del espíritu. Interpreta Eichmann en Jerusalén como una obra sobre el mal burocrático, pero sobre todo como estudio acerca de la responsabilidad, tanto jurídica como moral. De la historia de la voluntad resalta tres aspectos que pueden ser puestos en conexión con el problema de la responsabilidad: la ontología de la contingencia, la idea de individualidad vinculada a la voluntad y la capacidad de trascendencia y resistencia subyacentes en la teoría de Duns Escoto de la libertad como indiferencia. Por último, sugiere una vinculación entre la banalidad del mal y la ontología del bien desarrolladas en “Algunas cuestiones de filosofía moral”, de 1965-1966, la lucha contra el gnosticismo y la defensa de una relación entre moralidad e inteligibilidad del mal.

"Pedagogies of Resistance" and Critical Peace Education Praxis

Science.gov (United States)

Bajaj, Monisha

2015-01-01

This paper explores "pedagogies of resistance"--or critical and democratic educational models utilized by social movements--and how global examples of engaged educational praxis may inform peace education. The central inquiry of this article is "How can educational projects that resist larger social, political and economic…

Praxis educativa ecopacifista de enriquecimiento curricular: Conceptuacion, diseno y divulgacion

Science.gov (United States)

Osorio, Carlos Agustin Muniz

A general consensus exists that the present worldwide state of the natural environment is in crisis. Tied to this crisis, the social dimension presents a discouraging picture in aspects like violence and poverty. The predominant neoliberal economic system---ecocidal and genocidal---just as the production system that sustains it, affects this crisis. Puerto Rico, in its political and economic relationship with the United States of America, is not exempt of this situation. Education arises as an alternative to transform this reality. Science education has the potential to address these socio-environmental problems in a creative way. From a scientific educational framework, we conceptualized, designed and disseminated diverse approaches and tools that integrate socio-ecological and environmental aspects, as well as issues related to violence, conflict and peace. The central research questions were: At present, what are some of the main characteristics of the social-ecological and environmental global and local (glocal) issues and what relation do they have with formal education?; What is the ethical responsibility of science education when, facing social-ecological and environmental situations and issues concerning peace?; What educational foundations justify the "Praxis Educativa Ecopacifista de Enriquecimiento Curricular" as an alternative to the situations and issues considered?; What didactic tools do we propose?; What curricular design and revision processes do we propose? What dissemination processes do we propose? The nature of our methodology is qualitative and is centered around curricular design. It includes a research-theoretical dimension, a practical-research dimension, and systematizing of learning elements. We emphasize the conceptualization of the theoretical-philosophical and methodological dimensions of the ecopacifist approach and its fundamental principles. We highlight the praxis, integrating creativity, intelligence and talent development

La praxis en el pensamiento de Adolfo Sánchez Vázquez

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Manuel Uc Sánchez

2006-09-01

Full Text Available Sobre la base de las Tesis sobre Feuerbach de Marx, obra en la que se expone epigramáticamenteel núcleo teórico de la revolución marxista en la historia de la filosofía y en la concepción de la historia,surge un conjunto de autores que perciben dicha propuesta como filosofía de la praxis. Ejemplos ilustrativosson, entre los más relevantes: Antonio Labriola, seguido por Antonio Gramsci, G. Lukács, K. Korsch,los fundadores de la Escuela de Frankfurt y a partir de los años 50, participan en esta dirección críticaMaurice Marleau-Ponty y de la Revista Praxis Gajo Petrovic y Mihailo Markovic. Se destacan, además,los representantes de la Escuela de Budapest (Agnes Heller, Ferenc Feher, etc. así como Karel Kosic deChecoslovaquia y las reflexiones del francés Jean Paul Sartre, entre otros1, incluyendo desde luego al Dr.Adolfo Sánchez Vázquez, cuya eminente obra, Filosofía de la praxis, (1967 y 1980 desde el principiode la introducción delimita con profundidad su objetivo primordial:

O conceito de mal radical The concept of radical evil

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Adriano Correia

2005-01-01

Full Text Available A noção de mal radical aparece em Kant no contexto da discussão da religião nos limites da simples razão e busca dar conta da complexa relação entre o respeito pela lei moral e o amor-próprio na definição do móbil para a ação. Na busca por identificar o fundamento da propensão para o mal no homem, Kant se vê diante da dificuldade de ter de articular natureza e liberdade, e ainda que a noção de mal radical possa conservar algumas ambigüidades, permite conceber uma noção de responsabilidade compatível com uma inata propensão para o mal. Neste texto busco explicitar alguns passos fundamentais na construção do conceito por Kant.The concept of radical evil appears in Kant's theory when he discusses the religion in the limits of the mere reason and aims explain the complex relationship between respect for the moral law and the self-love, for establish the motive of the action. By aiming identify the basis of human inclination to evil, Kant is faced with the trouble of have to put nature and freedom in connection. Despite of the concept of radical evil retain some ambiguity, it allows conceive a notion of responsibility suitable to an inherent inclination to evil. In this paper is my purpose to explain some basic moments of Kantian formulation of that notion.

Theory and practice in psychoanalysis: psychoanalytic praxis. 1969.

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Bleger, José

2012-08-01

The author systematises and examines the relation between theory and practice in psychoanalysis in three directions: one, eminently epistemological, which is only mentioned because it pertains not only to psychoanalysis but to all the sciences; another, the relation between theory and technique; and the third, the relation between theory and the institutional organisation of psychoanalysis and psychoanalysts. All the problems described, especially the second and third points, together define psychoanalytic praxis. With regard to contradictions between theory and technique, the author points out that psychoanalytic theory is constructed fundamentally on the basis of an approach that is historico-genetic, dynamic and consistent with formal logic, whereas psychoanalytic practice occurs within a transference–countertransference relation, in a situation configured as an analytic field, a ‘here and now’, within a dramatic explanation and in a dialectic process. This triple diagnosis involves naturalistic and phenomenological approaches, the problem of objectivity and the role given to sexuality as a privileged parameter in psychoanalytic theory. In relation to the third direction mentioned above,the author refers briefly to the problem of psychoanalytic organisations, in the sense that they come into conflict with the development of psychoanalytic theory and the deepening of investigation. In reference to the latter, the author emphasises the need to widen the perspective of what constitutes psychoanalytic praxis. He points out that praxis is always replete with contradictions and that it is not a question of ignoring,denying or impeding these contradictions themselves (which would in any case be totally ineffective), but that by taking them into account, scientific development could be managed in a more planned way, less blindly; that is to say, less abandoned to spontaneity.

Mal de meleda with congenital cataract: A novel case report

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Anisha Sethi

2015-01-01

Full Text Available Mal de meleda (MdM, a rare autosomal recessive genodermatosis is characterized by erythema and hyperkeratosis of the palms and soles with a sharp demarcation and that progress with age (progrediens and extend to the dorsal aspects of the hands and feet (transgrediens. It has been associated with various conditions albeit rarely with congenial cataract. Ocular lens and the skin have the same embryological origins. We hereby present this novel case report of Mal de meleda in association with congenital posterior subcapsular cataract which to the best of our knowledge has not been reported from India before.

A zase ta malá povodí...

Czech Academy of Sciences Publication Activity Database

Tesař, Miroslav

2017-01-01

Roč. 67, č. 8 (2017), s. 33-38 ISSN 1211-0760. [Hydrologie malého povodí 2017. Praha, 18.04.2017-20.04.2017] Institutional support: RVO:67985874 Keywords : small basin * experimental hydrology * water balance * conference * watershed * hydrology * watershed Subject RIV: DA - Hydrology ; Limnology OBOR OECD: Hydrology

Maltase protein of Ogataea (Hansenula) polymorpha is a counterpart to the resurrected ancestor protein ancMALS of yeast maltases and isomaltases

Science.gov (United States)

Viigand, Katrin; Visnapuu, Triinu; Mardo, Karin; Aasamets, Anneli

2016-01-01

Abstract Saccharomyces cerevisiae maltases use maltose, maltulose, turanose and maltotriose as substrates, isomaltases use isomaltose, α‐methylglucoside and palatinose and both use sucrose. These enzymes are hypothesized to have evolved from a promiscuous α‐glucosidase ancMALS through duplication and mutation of the genes. We studied substrate specificity of the maltase protein MAL1 from an earlier diverged yeast, Ogataea polymorpha (Op), in the light of this hypothesis. MAL1 has extended substrate specificity and its properties are strikingly similar to those of resurrected ancMALS. Moreover, amino acids considered to determine selective substrate binding are highly conserved between Op MAL1 and ancMALS. Op MAL1 represents an α‐glucosidase in which both maltase and isomaltase activities are well optimized in a single enzyme. Substitution of Thr200 (corresponds to Val216 in S. cerevisiae isomaltase IMA1) with Val in MAL1 drastically reduced the hydrolysis of maltose‐like substrates (α‐1,4‐glucosides), confirming the requirement of Thr at the respective position for this function. Differential scanning fluorimetry (DSF) of the catalytically inactive mutant Asp199Ala of MAL1 in the presence of its substrates and selected monosaccharides suggested that the substrate‐binding pocket of MAL1 has three subsites (–1, +1 and +2) and that binding is strongest at the –1 subsite. The DSF assay results were in good accordance with affinity (K m) and inhibition (K i) data of the enzyme for tested substrates, indicating the power of the method to predict substrate binding. Deletion of either the maltase (MAL1) or α‐glucoside permease (MAL2) gene in Op abolished the growth of yeast on MAL1 substrates, confirming the requirement of both proteins for usage of these sugars. © 2016 The Authors. Yeast published by John Wiley & Sons, Ltd. PMID:26919272

Effect of postharvest storage on the expression of the apple allergen Mal d 1

NARCIS (Netherlands)

Sancho, Ana I.; Foxall, Robert; Browne, Tom; dey, Rickmer; Zuidmeer, Laurian; Marzban, Gorji; Waldron, Keith W.; van Ree, Ronald; Hoffmann-Sommergruber, Karin; Laimer, Margit; Mills, E. N. Clare

2006-01-01

Consumption of fresh apples can cause allergy in susceptible individuals. A competitive enzyme-linked immunosorbent assay (ELISA) has been developed to determine Mal d 1 levels in apple pulp using a monoclonal antibody (BIP-1). The ELISA was able to rank ten cultivars according to their Mal d 1

Introduction to Open Praxis volume 8 issue 3

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Inés Gil-Jaurena

2016-08-01

Full Text Available This third Open Praxis issue in 2016 is an open issue that includes six research papers and one book review. If this introduction I would like to deepen in the role of the Editorial team and present our Editorial Board past and current members, partially renewed in July 2016.

Religion and covenantal praxis in first century Judeanism

African Journals Online (AJOL)

p1243322

long term. Indeed, religion and covenantal praxis combined to make Judeanism a ... Socialization into all three social domains, the Temple, the synagogue, .... the American flag over an entrance to the mosque in Mecca. ..... The meat was to be eaten in the Temple, on the same day, sharing it ...... Celebrated by all Judeans.

Contribución al conocimiento de los malófagos (Phthiraptera, Amblycera, Ischnocera de aves peruanas. Parte 1

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Luis A. Gomez-Puerta

2015-12-01

Full Text Available En el presente trabajo se reporta nueve especies de malófagos colectados de aves peruanas. Dos malófagos Amblycera: Heteromenopon laticapitis y Menacanthus pici, así como siete malófagos Ischnocera: Alcedoffula theresae, Brueelia brunneinucha, Chelopistes meleagridis, Columbicola columbae, Paragoniocotes aratingae, Penenirmus jungens y Saemundssonia (Saemundssonia lari, fueron determinados mediante el diagnóstico morfológico. Se realiza una breve descripción de cada malófago, así como la discusión de sus hospederos y distribución.

Activist engineering: changing engineering practice by deploying praxis.

Science.gov (United States)

Karwat, Darshan M A; Eagle, Walter E; Wooldridge, Margaret S; Princen, Thomas E

2015-02-01

In this paper, we reflect on current notions of engineering practice by examining some of the motives for engineered solutions to the problem of climate change. We draw on fields such as science and technology studies, the philosophy of technology, and environmental ethics to highlight how dominant notions of apoliticism and ahistoricity are ingrained in contemporary engineering practice. We argue that a solely technological response to climate change does not question the social, political, and cultural tenet of infinite material growth, one of the root causes of climate change. In response to the contemporary engineering practice, we define an activist engineer as someone who not only can provide specific engineered solutions, but who also steps back from their work and tackles the question, What is the real problem and does this problem "require" an engineering intervention? Solving complex problems like climate change requires radical cultural change, and a significant obstacle is educating engineers about how to conceive of and create "authentic alternatives," that is, solutions that differ from the paradigm of "technologically improving" our way out of problems. As a means to realize radically new solutions, we investigate how engineers might (re)deploy the concept of praxis, which raises awareness in engineers of the inherent politics of technological design. Praxis empowers engineers with a more comprehensive understanding of problems, and thus transforms technologies, when appropriate, into more socially just and ecologically sensitive interventions. Most importantly, praxis also raises a radical alternative rarely considered-not "engineering a solution." Activist engineering offers a contrasting method to contemporary engineering practice and leads toward social justice and ecological protection through problem solving by asking not, How will we technologize our way out of the problems we face? but instead, What really needs to be done?

Praxis Exiled: Herbert Marcuse and the One Dimensional University

Science.gov (United States)

Cunningham, Joseph

2013-01-01

Leading Frankfurt School theorist, Herbert Marcuse, possessed an intricate relationship with higher education. As a professor, Marcuse participated in the 1960s student movements, believing that college students had potential as revolutionary subjects. Additionally, Marcuse advocated for a college education empowered by a form of praxis that…

Going Places: Praxis and Pedagogy in Australian Cultural Studies

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Rebecca Rey

2011-09-01

Full Text Available This article considers the pedagogical value of praxis in maintaining the relevance of cultural studies in the Australian academic environment. Following its highly politicised beginnings at the Birmingham Centre for Contemporary Cultural Studies, we consider whether traditional classroom practices are commensurate with the contemporary expectations of students and staff. As a working model of the current Australian university climate, we consider the discipline group of English and Cultural Studies (ECS at the University of Western Australia. After evaluating data gathered from interviews and surveys across the undergraduate, postgraduate and staff population, we suggest potential pedagogical innovations to be implemented in cultural studies at UWA, as a case study within Australia. Our findings show that students are calling for practical activities that would benefit their studies as a complement to theory in the classroom. As a result, we argue that praxis is not only important, but vital, in the teaching of cultural studies as an enabling activity that encourages the use of new teaching methods.

Manual praxis in stone tool manufacture: implications for language evolution.

Science.gov (United States)

Ruck, Lana

2014-12-01

Alternative functions of the left-hemisphere dominant Broca's region have induced hypotheses regarding the evolutionary parallels between manual praxis and language in humans. Many recent studies on Broca's area reveal several assumptions about the cognitive mechanisms that underlie both functions, including: (1) an accurate, finely controlled body schema, (2) increasing syntactical abilities, particularly for goal-oriented actions, and (3) bilaterality and fronto-parietal connectivity. Although these characteristics are supported by experimental paradigms, many researchers have failed to acknowledge a major line of evidence for the evolutionary development of these traits: stone tools. The neuroscience of stone tool manufacture is a viable proxy for understanding evolutionary aspects of manual praxis and language, and may provide key information for evaluating competing hypotheses on the co-evolution of these cognitive domains in our species. Copyright © 2014 Elsevier Inc. All rights reserved.

Interaction of PLP with GFP-MAL2 in the human oligodendroglial cell line HOG.

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Raquel Bello-Morales

Full Text Available The velocity of the nerve impulse conduction of vertebrates relies on the myelin sheath, an electrically insulating layer that surrounds axons in both the central and peripheral nervous systems, enabling saltatory conduction of the action potential. Oligodendrocytes are the myelin-producing glial cells in the central nervous system. A deeper understanding of the molecular basis of myelination and, specifically, of the transport of myelin proteins, will contribute to the search of the aetiology of many dysmyelinating and demyelinating diseases, including multiple sclerosis. Recent investigations suggest that proteolipid protein (PLP, the major myelin protein, could reach myelin sheath by an indirect transport pathway, that is, a transcytotic route via the plasma membrane of the cell body. If PLP transport relies on a transcytotic process, it is reasonable to consider that this myelin protein could be associated with MAL2, a raft protein essential for transcytosis. In this study, carried out with the human oligodendrocytic cell line HOG, we show that PLP colocalized with green fluorescent protein (GFP-MAL2 after internalization from the plasma membrane. In addition, both immunoprecipitation and immunofluorescence assays, indicated the existence of an interaction between GFP-MAL2 and PLP. Finally, ultrastructural studies demonstrated colocalization of GFP-MAL2 and PLP in vesicles and tubulovesicular structures. Taken together, these results prove for the first time the interaction of PLP and MAL2 in oligodendrocytic cells, supporting the transcytotic model of PLP transport previously suggested.

Praxis de la interrupción voluntaria del embarazo. Yo también fui zigoto

OpenAIRE

Queiruga Dios, Marián

2016-01-01

La praxis de la Interrupción Voluntaria del Embarazo es lo que se pret ende plantear en este estudio, con el subtítulo “yo también fui zigoto”, se personaliza la cuestión. Nos acercaremos a dicha praxis y haremos una valoración ética de la misma desde el ámbito filosófico: la licitud ética de la Interrupción Voluntaria del Embarazo.

Magnetic moment of short lived {beta}-emitter {sup 24m}Al

Energy Technology Data Exchange (ETDEWEB)

Nishimura, D., E-mail: daiki@vg.phys.sci.osaka-u.ac.jp; Komurasaki, J.; Matsuta, K.; Mihara, M.; Matsumiya, R. [Osaka University, Department of Physics (Japan); Momota, S. [Kochi University of Technology (Japan); Ohtsubo, T. [Niigata University, Department of Physics (Japan); Izumikawa, T. [Niigata University, RI Center (Japan); Hirano, H. [Niigata University, Department of Physics (Japan); Kitagawa, A.; Kanazawa, M.; Torikoshi, M.; Sato, S. [National Institute of Radiological Sciences (Japan); Fukuda, M.; Ishikawa, D. [Osaka University, Department of Physics (Japan); Minamisono, T. [Fukui University of Technology (Japan); Watanabe, R.; Kubo, T. [Niigata University, Department of Physics (Japan); Nojiri, Y. [Kochi University of Technology (Japan); Alonso, J. R. [Lawrence Berkeley Laboratory (United States)

2007-11-15

The magnetic moment of short lived {beta}-emitter {sup 24m}Al (426 keV, I{sup {pi}} = 1{sup +}, T{sub 1/2} = 131 ms) has been measured by means of {beta}-NMR technique, for the first time. From the {beta}-NMR spectrum, the magnetic moment was determined as |{mu}({sup 24m}Al)|=(2.99{+-}0.09){mu}{sub N}. Combined with the known magnetic moment of the mirror partner {sup 24m}Na, the expectation value of < S{sub z} > is obtained to be (0.08 {+-} 0.12). These values are reproduced well by the shell model calculation.

Malária grave em gestantes Severe malaria in pregnant women

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Flavia Barbosa Fernandes

2010-12-01

Full Text Available OBJETIVO: analisar a evolução clínica de três pacientes grávidas com malária grave internadas em unidade de terapia intensiva de um hospital localizado em Porto Velho (RO. MÉTODOS: foi realizado estudo descritivo em três gestantes, portadoras de malária por Plasmodium falciparum, internadas em unidade de terapia intensiva em Porto Velho, no período de 2005 a 2006. As variáveis categóricas utilizadas foram os critérios de classificação da Organização Mundial de Saúde para classificação de malária grave e os índices Acute Physiology and Chronic Health disease Classification System II (APACHE II e Sepsis Related Organ Failure Assessment (SOFA preditores de morbidade e gravidade das doenças em unidade de terapia intensiva. RESULTADOS: a malária adquirida pelas gestantes, caracterizada pela infecção por Plasmodium falciparum na forma grave da doença, resultou em óbito para as três pacientes e seus conceptos. CONCLUSÕES: embora a casuística seja pequena, a importância deste estudo reflete a repercussão da malária grave em gestantes, bem como a necessidade de um acompanhamento pré-natal mais criterioso e atento à identificação precoce do início das complicações da malária em gestantes.PURPOSE: to analyze the clinical course of three pregnant patients with severe malaria admitted to the intensive care unit of a hospital in Porto Velho (RO, Brazil. METHODS: a descriptive study was conducted on three pregnant women infected with Plasmodium falciparum malaria, admitted to the intensive care unit of a hospital in Porto Velho from 2005 to 2006. Categorical variables used were the classification criteria of the World Health Organization which ranks severe malaria and the Acute Physiology and Chronic Health Disease Classification System II (APACHE II and Sepsis Related Organ Failure Assessment (SOFA predictors of morbidity and severity of intensive care unit diseases. RESULTS: the malaria acquired by the pregnant

Praxis, subjectivity and sense

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Alfredo Gómez-Muller

2006-07-01

Full Text Available A primordial aspect of the Sartrian critique of alienation concerns understanding the analytic ideology as the domination of materiality over the symbolic, in other words as the reification of the human, and therefore as anticulture. In the context of contemporary nihilism, the decoding of the mechanisms which consign praxis to the practico-inert requires a critique of the relations between the social sciences and philosophy, which in its turn implies a new theory of the relation between what Sartre calls the "notion" (the area of subjectivity and the "concept" (objectivity, From this perspective, the deconstruction of the established frontiers between the social sciences and philosophy, and between the conceptual and the narrative, is corelative to a redefinition of the relation between theory and practice.

Glucose and maltose metabolism in MIG1-disrupted and MAL-constitutive strains of Saccharomyces cerevisiae

DEFF Research Database (Denmark)

Klein, Christopher; Olsson, Lisbeth; Rønnow, B

1997-01-01

in a mixed glucose-maltose medium revealed that the MAL-constitutive strains were more alleviated than the single MIG1-disrupted transformant. While all transformants exhibited higher maximum specific growth rates (0.24-0.25 h(-1)) in glucose-maltose mixtures than the wild type strain (0.20 h(-1)), the MAL-constitutive...

Ablative fractional laser enhances MAL-induced PpIX accumulation

DEFF Research Database (Denmark)

Haak, C S; Christiansen, K; Erlendsson, Andrés M

2016-01-01

BACKGROUND AND OBJECTIVES: Pretreatment of skin with ablative fractional laser enhances accumulation of topical provided photosensitizer, but essential information is lacking on the interaction between laser channel densities and pharmacokinetics. Hence our objectives were to investigate how...... (range 46-133min) induced fluorescence levels similar to curettage and 180min incubation. Furthermore, MAL 80 and 160mg/g induced similar fluorescence intensities in skin exposed to laser densities of 1, 2 and 5% (p>0.0537, 30-180min). CONCLUSION: MAL-induced protoporphyrin accumulation is augmented...... protoporphyrin accumulation was affected by laser densities, incubation time and drug concentration. METHODS: We conducted the study on the back of healthy male volunteers (n=11). Test areas were pretreated with 2940nm ablative fractional Er:YAG laser, 11.2mJ per laser channel using densities of 1, 2, 5, 10...

"MathePraxis"--Connecting First-Year Mathematics with Engineering Applications

Science.gov (United States)

Harterich, Jorg; Kiss, Christine; Rooch, Aeneas; Monnigmann, Martin; Darup, Moritz Schulze; Span, Roland

2012-01-01

First-year engineering students often complain about their mathematics courses as the significance of the difficult and abstract calculus to their field of study remains unclear. We report on the project "MathePraxis", a feasibility study which was designed as a means to give first-year students some impression about the use of…

Artistic Praxis and the Neoliberalization of the Educational Space

Science.gov (United States)

Gielen, Pascal

2013-01-01

Referring to the work of Richard Sennett, this article puts forth the proposition that art production is possible only when there is a correct relation between theory and artistic practice. An effective artistic praxis can only be realized by incorporating theory in artistic practices. Based on empirical research, the author elaborates on the…

Mal, daño y justicia

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Carlos THIEBAUT

2009-11-01

Full Text Available RESUMEN: Algunas experiencias del siglo XX -Auschwitz, el Gulag, Hiroshima- han vuelto a herir la conciencia ilustrada y replanteado el problema del mal en nuestra cultura. Más que una indagación metafísica sobre la naturaleza del mal, el artículo aboga por un análisis de cómo llegamos a elaborar su experiencia, un proceso que aquí prefiere concebirse como una indagación en torno al daño. Se analizan las estructuras conceptuales, modales y temporales de esa experiencia y, en la segunda parte, se propone la idea de que la elaboración pública del daño es una clave para comprender la dimensión normativa del espacio público.ABSTRACT: Some experiences of the Twentieth Century have, yet again, wounded the Enlightment program and have rephrased the problem of evil in our culture. The article avoids a metaphysical inquiry into the essence of evil and proposes an analysis of how we come to work and elabórate its experience, a process that is here understood as the experience of harm. Its conceptual, modal and temporal structures are analysed and, in its second part, the idea that the public labouring of harm is a clue to understanding the normative dimensión of the public sphere is proposed.

Comparing motor performance, praxis, coordination, and interpersonal synchrony between children with and without Autism Spectrum Disorder (ASD).

Science.gov (United States)

Kaur, Maninderjit; M Srinivasan, Sudha; N Bhat, Anjana

2018-01-01

Children with Autism Spectrum Disorder (ASD) have basic motor impairments in balance, gait, and coordination as well as autism-specific impairments in praxis/motor planning and interpersonal synchrony. Majority of the current literature focuses on isolated motor behaviors or domains. Additionally, the relationship between cognition, symptom severity, and motor performance in ASD is unclear. We used a comprehensive set of measures to compare gross and fine motor, praxis/imitation, motor coordination, and interpersonal synchrony skills across three groups of children between 5 and 12 years of age: children with ASD with high IQ (HASD), children with ASD with low IQ (LASD), and typically developing (TD) children. We used the Bruininks-Oseretsky Test of Motor Proficiency and the Bilateral Motor Coordination subtest of the Sensory Integration and Praxis Tests to assess motor performance and praxis skills respectively. Children were also examined while performing simple and complex rhythmic upper and lower limb actions on their own (solo context) and with a social partner (social context). Both ASD groups had lower gross and fine motor scores, greater praxis errors in total and within various error types, lower movement rates, greater movement variability, and weaker interpersonal synchrony compared to the TD group. In addition, the LASD group had lower gross motor scores and greater mirroring errors compared to the HASD group. Overall, a variety of motor impairments are present across the entire spectrum of children with ASD, regardless of their IQ scores. Both, fine and gross motor performance significantly correlated with IQ but not with autism severity; however, praxis errors (mainly, total, overflow, and rhythmicity) strongly correlated with autism severity and not IQ. Our study findings highlight the need for clinicians and therapists to include motor evaluations and interventions in the standard-of-care of children with ASD and for the broader autism community to

MAL2 and tumor protein D52 (TPD52 are frequently overexpressed in ovarian carcinoma, but differentially associated with histological subtype and patient outcome

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Fanayan Susan

2010-09-01

Full Text Available Abstract Background The four-transmembrane MAL2 protein is frequently overexpressed in breast carcinoma, and MAL2 overexpression is associated with gain of the corresponding locus at chromosome 8q24.12. Independent expression microarray studies predict MAL2 overexpression in ovarian carcinoma, but these had remained unconfirmed. MAL2 binds tumor protein D52 (TPD52, which is frequently overexpressed in ovarian carcinoma, but the clinical significance of MAL2 and TPD52 overexpression was unknown. Methods Immunohistochemical analyses of MAL2 and TPD52 expression were performed using tissue microarray sections including benign, borderline and malignant epithelial ovarian tumours. Inmmunohistochemical staining intensity and distribution was assessed both visually and digitally. Results MAL2 and TPD52 were significantly overexpressed in high-grade serous carcinomas compared with serous borderline tumours. MAL2 expression was highest in serous carcinomas relative to other histological subtypes, whereas TPD52 expression was highest in clear cell carcinomas. MAL2 expression was not related to patient survival, however high-level TPD52 staining was significantly associated with improved overall survival in patients with stage III serous ovarian carcinoma (log-rank test, p Conclusions MAL2 is frequently overexpressed in ovarian carcinoma, and TPD52 overexpression is a favourable independent prognostic marker of potential value in the management of ovarian carcinoma patients.

La seducción del mal en Estrella Distante de Roberto Bolaño

OpenAIRE

Montes, Cristian

2013-01-01

En el presente artículo se trabajará en torno a la novela Estrella distante de Roberto Bolaño. La intención del análisis será demostrar cómo se expresa y opera la seducción del mal al interior de la representación y proponer cuáles son las formas en que el mal encarna en una figura representativa de la dictadura militar chilena.

Performances of air source heat pump system for a kind of mal-defrost phenomenon appearing in moderate climate conditions

International Nuclear Information System (INIS)

Wang, W.; Feng, Y.C.; Zhu, J.H.; Li, L.T.; Guo, Q.C.; Lu, W.P.

2013-01-01

Highlights: ► Mal-defrost performances of ASHP in moderate environment are investigated. ► The system COP decreases to 2.3 under environment temperature of 7.9 °C. ► The decrease of the ASHP heating capacity can get to 43.4%. ► The origins of this special mal-defrost phenomenon were discussed. ► Suggestions were proposed to modify the current defrosting control strategies. - Abstract: To quantify the performance drop of the air source heat pump (ASHP) system under a special kind of mal-defrost phenomenon appearing in moderate climate conditions, a field test was conducted for 8 days at the initial stage of a heating season in Beijing, China. The mal-defrost was found with the more than 60% frosted area of the outdoor heat exchanger after the system running 5 days. During this frosting period, the system COP was significantly degraded, only 2.3 under an environment temperature of 7.9 °C. Comparing the test data before and after frosting, it was found that the mal-defrost decreased the COP up to 40.4% and the heating capacity to 43.4%. Such low energy efficiency continued quite a long time until the defrost control was started up manually by the authors. After defrosting, the COP reclaimed to the normal level of 5.0. The origins of this special mal-defrost phenomenon were discussed. And some suggestions were proposed to modify the current defrosting control strategy, which were helpful to avoid the mal-defrost problem in the current ASHP system and therefore improve the system performances

RPL as cognitive praxis in linking higher education, the African ...

African Journals Online (AJOL)

This article argues that we can use the Recognition of Prior Learning (RPL) to reconceptualise the project of bridging the articulation gap between further and higher education in South Africa by framing the cognitive praxis of this project simultaneously within the African Renaissance and within a progressive global project ...

Social Justice Leadership as Praxis: Developing Capacities through Preparation Programs

Science.gov (United States)

Furman, Gail

2012-01-01

Purpose: The purpose of this article is to propose a conceptual framework for social justice leadership as praxis and to explore the implications of this framework for leadership preparation programs. Conceptual Argument: The conceptual framework for social justice leadership is grounded in a review of literature and organized around three central…

Pearson-Praxis Assessments Review Teacher Certification Assessment Technology Education: A Report for the Council on Technology and Engineering Teacher Education

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Mahoney, Mark P.

2015-01-01

The Praxis Series, developed by Educational Testing Services (ETS), has been the long standing assessment for teacher licensure. It is comprised of three separate skills examinations: (1) Praxis Core Academic Skills for Educators (Core) (attempts to measure academic skills in reading, writing, and mathematics; content knowledge of candidates…

[Science, public health and nursing: highlighting the gender and generation categories in the episteme of praxis].

Science.gov (United States)

Egry, Emiko Yoshikawa; da Fonseca, Rosa Maria Godoy Serpa; Oliveira, Maria Amélia de Campos

2013-09-01

This essay aims to show the relevance of sociological categories gender and generation that underlie the phenomenon of nursing in public health, the episteme of praxis. We understand praxis as the foundation of the historical and dialectic materialism, demonstrating its importance in the process of construction of knowledge in public health nursing. The sociological categories of gender and generation were chosen in this paper because it has the privilege to better illuminate certain phenomena that have been the subject of scientific concern, such as violence against women, children and the elderly, in all its vulnerabilities. The dialectical method was adopted, with an emphasis on the secondary laws of "essence and phenomena" and "reality and possibility". Finally, given that the choice of the approach to the object, as well as the instruments for intervention towards a purpose in the process of scientific knowledge is the choice of the knowing subject, the ethics was related to praxis.

Torsional vibration analysis in turbo-generator shaft due to mal-synchronization fault

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Bangunde, Abhishek; Kumar, Tarun; Kumar, Rajeev; Jain, S. C.

2018-03-01

A rotor of turbo-generator shafting is many times subjected to torsional vibrations during its lifespan. The reasons behind these vibrations are three-Phase fault, two-phase fault, line to ground fault, faulty-mal synchronization etc. Sometimes these vibrations can cause complete failure of turbo-generator shafting system. To calculate moment variation during these faults on the shafting system vibration analysis is done using Finite Elements Methods to calculate mass and stiffness matrix. The electrical disturbance caused during Mal-synchronization is put on generator section, and corresponding second order equations are solved by using “Duhamel Integral”. From the moment variation plots at four sections critically loaded sections are identified.

Brucella TIR-like protein TcpB/Btp1 specifically targets the host adaptor protein MAL/TIRAP to promote infection.

Science.gov (United States)

Li, Wenna; Ke, Yuehua; Wang, Yufei; Yang, Mingjuan; Gao, Junguang; Zhan, Shaoxia; Xinying, Du; Huang, Liuyu; Li, Wenfeng; Chen, Zeliang; Li, Juan

2016-08-26

Brucella spp. are known to avoid host immune recognition and weaken the immune response to infection. Brucella like accomplish this by employing two clever strategies, called the stealth strategy and hijacking strategy. The TIR domain-containing protein (TcpB/Btp1) of Brucella melitensis is thought to be involved in inhibiting host NF-κB activation by binding to adaptors downstream of Toll-like receptors. However, of the five TIR domain-containing adaptors conserved in mammals, whether MyD88 or MAL, even other three adaptors, are specifically targeted by TcpB has not been identified. Here, we confirmed the effect of TcpB on B.melitensis virulence in mice and found that TcpB selectively targets MAL. By using siRNA against MAL, we found that TcpB from B.melitensis is involved in intracellular survival and that MAL affects intracellular replication of B.melitensis. Our results confirm that TcpB specifically targets MAL/TIRAP to disrupt downstream signaling pathways and promote intra-host survival of Brucella spp. Copyright © 2016 Elsevier Inc. All rights reserved.

The Powers of the Exploited and the Social Ontology of Praxis

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Michael Hardt

2018-05-01

Full Text Available This contribution is the first part of a debate between Michael Hardt/Toni Negri and David Harvey on the occasion of Marx’s bicentenary. The discussion focuses on the question of what capitalism looks like today and how it can best be challenged. This contribution asks: In what type of capitalist society are we living today? And what is the Marxian praxis that we need to challenge it? First, this paper analyses capitalism in respect to the extraction of value from the common, immaterial labour, digitisation, automation, and finance capital. The greatest abstraction in the productive process of value, in its implementation of languages, codes, immaterial articulations of being together, cooperation, affective elements, and so forth presents also in the multitude the virtuality of an extraordinary potential of resistance and autonomy from capital. Second, the paper discusses what forms of praxis are needed today. Marxian ontology is constituted and always renewed by class struggle, by the material antagonism that distributes the elements of real being and by the continuous excess of value that living labour expresses. Today, we discuss Marxian praxis in a society where intelligence is put to work at the centre of the productive process. Here emerges with great force the theme of the liberation of humans from work, on the basis of the transformations of work. Marx demonstrates how much cognitive and intellectual activity is central to production, and how much fixed capital is mixed with cognitive labour. In this context, the notion of the appropriation of fixed capital is of key importance for class struggles.

El mal de ojo y su relación con el marasmo y kwashiorkor: El caso de las madres de Turbo, Antioquia, Colombia Mal de ojo and its relationship with marasm and kwashiorkor: the Turbo mother’s case

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Gildardo Uribe Gil

2007-03-01

Full Text Available Objetivo: Describir las percepciones y prácticas socio-culturales de las madres frente al proceso de desnutrición aguda grave de los niños: marasmo y kwashiorkor. Metodología: Etnografía descriptiva. Se realizaron 20 entrevistas semiestructuradas, 2 entrevistas grupales y observación en los hogares y en el hospital. El análisis se realizó manualmente. Resultados: Las madres perciben la desnutrición aguda grave como una consecuencia del mal de ojo, el cual afecta a los niños menores de 7 años. El mal de ojo se clasifica como "ojo secador" y "ojo de la calle". Para las madres, el ojo secador enmagrece totalmente a los niños, lo cual podríamos asimilar al marasmo. No es claro si el ojo de la calle conlleva al kwashiorkor, pero es claro que el kwashirkor es causado por el mal de ojo. Los médicos tradicionales, como los rezanderos, ocupan un lugar importante en el tratamiento de las enfermedades de filiación cultural. Conclusiones: En el modelo biomédico no existen ni el mal de ojo ni la desnutrición como enfermedad. La desnutrición se conceptúa como estado y finalmente se objetiviza en cifras estadísticas, lo cual dificulta la atención integral de los niños. El estudio devela un mundo desconocido por el sistema biomédico, y un mundo de prácticas culturales frente al proceso de desnutrición, que adecuadamente valoradas permitirían mejorar la atención integral y evitar la muerte infantil por desnutrición aguda grave o por el mal de ojo.Objective: To describe perceptions and socio- cultural practices by the mothers facing severe malnutrition in children: Marasm and Kwashiorkor. Methodology: Descriptive ethnography. Twenty semi-structured interviews and two tribal ones were carried. Homes and hospitalized children were observed. Analysis was manually performed. Results: Mother perceives severe malnutrition like "mal de ojo" consequence afflicting children under seven. Mal de ojo is classified as "drying-eye" or as "street

A Novel Bifunctional Amino Acid Racemase With Multiple Substrate Specificity, MalY From Lactobacillus sakei LT-13: Genome-Based Identification and Enzymological Characterization

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Shiro Kato

2018-03-01

Full Text Available The Lactobacillus sakei strain LK-145 isolated from Moto, a starter of sake, produces potentially large amounts of three D-amino acids, D-Ala, D-Glu, and D-Asp, in a medium containing amylase-digested rice as a carbon source. The comparison of metabolic pathways deduced from the complete genome sequence of strain LK-145 to the type culture strain of Lactobacillus sakei strain LT-13 showed that the L- and D-amino acid metabolic pathways are similar between the two strains. However, a marked difference was observed in the putative cysteine/methionine metabolic pathways of strain LK-145 and LT-13. The cystathionine β-lyase homolog gene malY was annotated only in the genome of strain LT-13. Cystathionine β-lyase is an important enzyme in the cysteine/methionine metabolic pathway that catalyzes the conversion of L-cystathionine into L-homocysteine. In addition to malY, most genome-sequenced strains of L. sakei including LT-13 lacked the homologous genes encoding other putative enzymes in this pathway. Accordingly, the cysteine/methionine metabolic pathway likely does not function well in almost all strains of L. sakei. We succeeded in cloning and expressing the malY gene from strain LT-13 (Ls-malY in the cells of Escherichia coli BL21 (DE3 and characterized the enzymological properties of Ls-MalY. Spectral analysis of purified Ls-MalY showed that Ls-MalY contained a pyridoxal 5′-phosphate (PLP as a cofactor, and this observation agreed well with the prediction based on its primary structure. Ls-MalY showed amino acid racemase activity and cystathionine β-lyase activity. Ls-MalY showed amino acid racemase activities in various amino acids, such as Ala, Arg, Asn, Glu, Gln, His, Leu, Lys, Met, Ser, Thr, Trp, and Val. Mutational analysis revealed that the -amino group of Lys233 in the primary structure of Ls-MalY likely bound to PLP, and Lys233 was an essential residue for Ls-MalY to catalyze both the amino acid racemase and β-lyase reactions. In

Hacia una praxis territorial

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Clara Olóriz Sanjuán

2017-01-01

Full Text Available Hoy, la profesión de la arquitectura se ha visto disminuida y el impacto de la disciplina, en algunos casos, es casi irrelevante para la producción de nuestro mundo contemporáneo. En comparación con otras profesiones, economistas, políticos, desarrolladores, científicos de la computación; los arquitectos juegan un modesto papel en la configuración social, política y física de nuestro mundo. Pareciera que con mayor frecuencia la arquitectura le importa sólo a los arquitectos, puesto que el trabajo que se produce es admirado por la singularidad del objeto diseñado. Es elogiado por su capacidad técnica o características estéticas, pero fuera del ámbito de la vida cotidiana de la mayoría de las personas. Dentro del Programa de Posgrado Landscape Urbanism del Architectural Association School of Architecture y el estudio Groundlab, se aborda el surgimiento del “territorio” como campo para el ejercicio del diseño e investigación y como forma de intervenirlo mediante el diseño, con la finalidad de incorporar la arquitectura dentro de un marco cada vez más amplio y a la luz de la urgentes condiciones contemporáneas. Within current contemporary conditions the profession of Architecture has been diminished and the impact of the discipline in some cases is almost irrelevant to the production of our contemporary world. Compare to other professions, economists, politicians, developers, policy-makers, computer scientists, architecture plays a tiny role in shaping our world, socially, politically and physically. Architecture seems to increasingly matter only to architects and the work that is produced admired for the singularity of the designed object. It is praised by its technical ability or aesthetical features but outside the realm of the majority’s everyday life. In this essay we explain the emergence of “territory” as a field of design praxis as research and praxis by the Landscape Urbanism Master Programme at the

Praxis II mathematics content knowledge test (0061)

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McCune, Ennis Donice

2007-01-01

Your guide to a higher score on the Praxis II?: Mathematics Content Knowledge Test (0061) Why CliffsTestPrep Guides? Go with the name you know and trust Get the information you need--fast! Written by test-prep specialists About the contents: Introduction * Overview of the exam * How to use this book * Proven study strategies and test-taking tips Part I: Subject Review * Focused review of all exam topics: arithmetic and basic algebra, geometry, trigonometry, analytic geometry, functions and their graphs, calculus, probability and statistics, discrete mathematics, linear algebra, compute

High temperature increases the masculinization rate of the all-female (XX) rainbow trout "Mal" population.

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Valdivia, Karina; Jouanno, Elodie; Volff, Jean-Nicolas; Galiana-Arnoux, Delphine; Guyomard, René; Helary, Louise; Mourot, Brigitte; Fostier, Alexis; Quillet, Edwige; Guiguen, Yann

2014-01-01

Salmonids are generally considered to have a robust genetic sex determination system with a simple male heterogamety (XX/XY). However, spontaneous masculinization of XX females has been found in a rainbow trout population of gynogenetic doubled haploid individuals. The analysis of this masculinization phenotype transmission supported the hypothesis of the involvement of a recessive mutation (termed mal). As temperature effect on sex differentiation has been reported in some salmonid species, in this study we investigated in detail the potential implication of temperature on masculinization in this XX mal-carrying population. Seven families issued from XX mal-carrying parents were exposed from the time of hatching to different rearing water temperatures ((8, 12 and 18°C), and the resulting sex-ratios were confirmed by histological analysis of both gonads. Our results demonstrate that masculinization rates are strongly increased (up to nearly two fold) at the highest temperature treatment (18°C). Interestingly, we also found clear differences between temperatures on the masculinization of the left versus the right gonads with the right gonad consistently more often masculinized than the left one at lower temperatures (8 and 12°C). However, the masculinization rate is also strongly dependent on the genetic background of the XX mal-carrying families. Thus, masculinization in XX mal-carrying rainbow trout is potentially triggered by an interaction between the temperature treatment and a complex genetic background potentially involving some part of the genetic sex differentiation regulatory cascade along with some minor sex-influencing loci. These results indicate that despite its rather strict genetic sex determinism system, rainbow trout sex differentiation can be modulated by temperature, as described in many other fish species.

Delayed surgical treatment for neglected or mal-reduced talar fractures.

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Huang, Peng-Ju; Cheng, Yuh-Min

2005-10-01

From 1993 to 2002, we treated nine patients for neglected or mal-reduced talar fractures. Average patient age was 39 (20-64) years and average follow-up 53 months. The time interval between injury and index operation ranged from 4 weeks to 4 years. Surgical procedures included open reduction with or without bone grafting in six cases, open reduction combined with ankle fusion in one case, talar neck osteotomy in one case, and talar neck osteotomy combined with subtalar fusion in one case. All cases had solid bone union. One patient developed avascular necrosis of the talus needing subsequent ankle arthrodesis. In six patients, adjacent hindfoot arthrosis occurred. The overall AOFAS ankle-hindfoot score was in average 77.4. We conclude that in neglected and mal-reduced talar fractures, surgical treatment can lead to a favourable outcome if the hindfoot joints are not arthritic.

MAL2 and tumor protein D52 (TPD52) are frequently overexpressed in ovarian carcinoma, but differentially associated with histological subtype and patient outcome

International Nuclear Information System (INIS)

Byrne, Jennifer A; Sutherland, Robert L; Fazio, Anna de; O'Brien, Philippa M; Maleki, Sanaz; Hardy, Jayne R; Gloss, Brian S; Murali, Rajmohan; Scurry, James P; Fanayan, Susan; Emmanuel, Catherine; Hacker, Neville F

2010-01-01

The four-transmembrane MAL2 protein is frequently overexpressed in breast carcinoma, and MAL2 overexpression is associated with gain of the corresponding locus at chromosome 8q24.12. Independent expression microarray studies predict MAL2 overexpression in ovarian carcinoma, but these had remained unconfirmed. MAL2 binds tumor protein D52 (TPD52), which is frequently overexpressed in ovarian carcinoma, but the clinical significance of MAL2 and TPD52 overexpression was unknown. Immunohistochemical analyses of MAL2 and TPD52 expression were performed using tissue microarray sections including benign, borderline and malignant epithelial ovarian tumours. Inmmunohistochemical staining intensity and distribution was assessed both visually and digitally. MAL2 and TPD52 were significantly overexpressed in high-grade serous carcinomas compared with serous borderline tumours. MAL2 expression was highest in serous carcinomas relative to other histological subtypes, whereas TPD52 expression was highest in clear cell carcinomas. MAL2 expression was not related to patient survival, however high-level TPD52 staining was significantly associated with improved overall survival in patients with stage III serous ovarian carcinoma (log-rank test, p < 0.001; n = 124) and was an independent predictor of survival in the overall carcinoma cohort (hazard ratio (HR), 0.498; 95% confidence interval (CI), 0.34-0.728; p < 0.001; n = 221), and in serous carcinomas (HR, 0.440; 95% CI, 0.294-0.658; p < 0.001; n = 182). MAL2 is frequently overexpressed in ovarian carcinoma, and TPD52 overexpression is a favourable independent prognostic marker of potential value in the management of ovarian carcinoma patients

Pequeno mal epiléptico em crianças. Considerações sobre o efeito do tridione em 4 casos

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Antonio B. Lefévre

1949-03-01

Full Text Available The author administered Tridione in four patients under five years of age with "petit mal" seizures. In all cases there was complete disappearance of the seizures eventhough small doses were used. In one case the EEG, taken after the Tridione treatment, did not show the previous "petit mal" pattern. In no case there were signs of intolerance. In conclusion the author thoroughly agree that Tridione is the drug of choice in "petit mal" seizures.

El problema del mal y la violencia en Colombia

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Victor Eligio Espinosa Galán

2015-09-01

Full Text Available La historia de la humanidad está marcada por conflictos de distinta naturaleza: religiosos, ideológicos, raciales, etc., expresados en guerras, ataques terroristas, masacres, entre muchas otras situaciones de crueldad que muestran maldad y sevicia ejercida sobre seres humanos. Ante estos acontecimientos que nos enfrentan a la pregunta: ¿qué es aquello que nos hace humanos?, parece, en un contexto como el colombiano, que se asiste a formas oficiales de una agencia de maldad como posibilidad de un ethos cultural que hace plausibles las acciones más perversas en una desoladora minimización de responsabilidad moral, necesaria para construcción de una sociedad justa y en paz. Este escrito es un esfuerzo por pensar el problema del mal en el contexto de la violencia en Colombia y dar cuenta de algunos aspectos de la reflexión filosófica sobre el mal, el sufrimiento y el sentido de la vida; se toma como contexto el conflicto armado en Colombia y las narraciones de sus protagonistas.

Exposure to Glycolytic Carbon Sources Reveals a Novel Layer of Regulation for the MalT Regulon

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Sylvia A. Reimann

2011-01-01

Full Text Available Bacteria adapt to changing environments by means of tightly coordinated regulatory circuits. The use of synthetic lethality, a genetic phenomenon in which the combination of two nonlethal mutations causes cell death, facilitates identification and study of such circuitry. In this study, we show that the E. coli ompR malTcon double mutant exhibits a synthetic lethal phenotype that is environmentally conditional. MalTcon, the constitutively active form of the maltose system regulator MalT, causes elevated expression of the outer membrane porin LamB, which leads to death in the absence of the osmoregulator OmpR. However, the presence and metabolism of glycolytic carbon sources, such as sorbitol, promotes viability and unveils a novel layer of regulation within the complex circuitry that controls maltose transport and metabolism.

DMPD: The Troll in Toll: Mal and Tram as bridges for TLR2 and TLR4 signaling. [Dynamic Macrophage Pathway CSML Database

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Full Text Available 17449723 The Troll in Toll: Mal and Tram as bridges for TLR2 and TLR4 signaling. Sh...Show The Troll in Toll: Mal and Tram as bridges for TLR2 and TLR4 signaling. PubmedID 17449723 Title The Tro...ll in Toll: Mal and Tram as bridges for TLR2 and TLR4 signaling. Authors Sheedy F

Discourses and Social Praxis of Entrepreneurship. A Glance from the Critical Discourse Analysis Discursos y praxis social del emprendimiento. Una mirada desde el análisis crítico del discurso

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Jaime Andrés Ararat Herrera

2009-06-01

Full Text Available The objective of this article is to socialize some findings related to the understanding of the discourses that guide the teaching of entrepreneurship in Higher Education Institutions in Medellin city. It is explored through a qualitative approach and the Critical Discourse Analysis Methodology, its "construction" through the discursive practices with people in charge of the social praxis of the analyzed institutions. It identifies commonalities and differentiators that support the "discourse" (values, ideologies and discursive devices used in each. The information was gathered through semi structured interviews and textual analysis of the structure of institutional newspaper news. It also provided an institutional context in which students understand, memorize and use the entrepreneurship information for their social praxis. In the given discourse, the use of semantic macrostructures is evident, providing cohesion and coherence in each of the analyzed institutions. Con el artículo se pretende socializar algunos hallazgos relacionados con la comprensión de los discursos que orientan la enseñanza del emprendimiento en las Instituciones de Educación Superior de la ciudad de Medellín. Se examina, mediante un enfoque cualitativo y una metodología de Análisis Crítico del Discurso, la “construcción” de los mismos, a través de las prácticas discursivas de los encargados de orientar su praxis social en las entidades analizadas. Se identifican aspectos comunes y diferenciadores que soportan dicho “discurso” (valores, ideologías y dispositivos discursivos utilizados en cada una de ellas. La información se recopiló a través de entrevistas semiestructuradas y análisis de la estructura textual de noticias en periódicos institucionales. Se proporcionó también un contexto institucional en donde los estudiantes entienden, memorizan y utilizan la información del emprendimiento para su praxis social. En el discurso emitido se evidencia

Structural complementarity of Toll/interleukin-1 receptor domains in Toll-like receptors and the adaptors Mal and MyD88.

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Dunne, Aisling; Ejdeback, Mikael; Ludidi, Phumzile L; O'Neill, Luke A J; Gay, Nicholas J

2003-10-17

The Toll/interleukin 1 receptor (TIR) domain is a region found in the cytoplasmic tails of members of the Toll-like receptor/interleukin-1 receptor superfamily. The domain is essential for signaling and is also found in the adaptor proteins Mal (MyD88 adaptor-like) and MyD88, which function to couple activation of the receptor to downstream signaling components. Experimental structures of two Toll/interleukin 1 receptor domains reveal a alpha-beta-fold similar to that of the bacterial chemotaxis protein CheY, and other evidence suggests that the adaptors can make heterotypic interactions with both the receptors and themselves. Here we show that the purified TIR domains of Mal and MyD88 can form stable heterodimers and also that Mal homodimers and oligomers are dissociated in the presence of ATP. To identify structural features that may contribute to the formation of signaling complexes, we produced models of the TIR domains from human Toll-like receptor 4 (TLR4), Mal, and MyD88. We found that although the overall fold is conserved the electrostatic surface potentials are quite distinct. Docking studies of the models suggest that Mal and MyD88 bind to different regions in TLRs 2 and 4, a finding consistent with a cooperative role of the two adaptors in signaling. Mal and MyD88 are predicted to interact at a third non-overlapping site, suggesting that the receptor and adaptors may form heterotetrameric complexes. The theoretical model of the interactions is supported by experimental data from glutathione S-transferase pull-downs and co-immunoprecipitations. Neither theoretical nor experimental data suggest a direct role for the conserved proline in the BB-loop in the association of TLR4, Mal, and MyD88. Finally we show a sequence relationship between the Drosophila protein Tube and Mal that may indicate a functional equivalence of these two adaptors in the Drosophila and vertebrate Toll pathways.

Maturity and storage influence on the apple (Malus domestica) allergen Mal d 3, a nonspecific lipid transfer protein

NARCIS (Netherlands)

Sancho, Ana I.; Foxall, Robert; Rigby, Neil M.; Browne, Thomas; Zuidmeer, Laurian; van Ree, Ronald; Waldron, Keith W.; Mills, E. N. Clare

2006-01-01

Consumption of apples can provoke severe allergic reactions, in susceptible individuals, due to the presence of the allergen Mal d 3, a nonspecific lipid transfer protein, found largely in the fruit skin. Levels of Mal d 3 were determined in peel as a function of apple cultivar, position of the

The Importance of "Praxis" in Financial Literacy Education: An Indigenous Perspective

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Blue, Levon; Grootenboer, Peter; Brimble, Mark

2015-01-01

We argue the importance of "praxis" in financial literacy education teaching practices that is, the moral and ethical nature of teaching and learning. Post the global financial crisis of 2008, the teaching of financial literacy has become a priority for many countries. Indigenous communities are often the target of broad FLE strategies…

Battling Inertia in Educational Leadership: CRT Praxis for Race Conscious Dialogue

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Agosto, Vonzell; Karanxha, Zorka; Bellara, Aarti

2015-01-01

The purpose of this article is to illustrate how institutional racism is mediated by faculty negotiating power and privilege in the selection of Black (African American) women into an educational leadership preparation program. Critical race theory (CRT) praxis is used to analyze the faculty dynamics in the candidate selection process situated in…

Human Praxis: A New Basic Assumption for Art Educators of the Future.

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Hodder, Geoffrey S.

1980-01-01

After analyzing Vincent Lanier's five characteristic roles of art education, the article briefly explains the pedagogy of Paulo Freire, based on human praxis, and applies it to the existing "oppresive" art education system. The article reduces Lanier's roles to resemble a single Freirean model. (SB)

"Kevad uhkelt sammub mal kui jumalanna..." : [luuletused] / Ljubov Dergatshova ; tlk. Arvo Valton

Index Scriptorium Estoniae

Dergatshova, Ljubov

2006-01-01

Sisu: "Kevad uhkelt sammub mal kui jumalanna..." ; "Maga, pojake, maga mu päike..." ; "Mis kaunis õhtu! Lumi tahke..." ; "Raskel tunnil sirutab kes käe...". Luuletused paralleelselt ersa ja eesti keeles

La Seducción del mal en estrella distante de Roberto Bolaño

OpenAIRE

Montes, Cristian

2013-01-01

En el presente artículo se trabajará en torno a la novela Estrella distante de Roberto Bolaño. La intención del análisis será demostrar cómo se expresa y opera la seducción del mal al interior de la representación y proponer cuáles son las formas en que el mal encarna en una figura representativa de la dictadura militar chilena. This article is based on the Roberto Bolaño novel Estrella Distante. The analysis aims to demonstrate the ways that the seduction of evil is expressed and operates...

Rotational Mal-Alignment after Reamed Intramedullary Nailing for tibial shaft fracture.

Science.gov (United States)

Khan, Sher Baz; Mohib, Yasir; Rashid, Rizwan Haroon; Rashid, Haroonur

2016-10-01

Intra-medullary (IM) nailing is standard of care for unstable tibial shaft fractures. Malrotation is very common but it is under-recognised, inpart because of variation in normal anatomy and partly due to difficulty in accurately assessing rotation. This study was planned to evaluate the frequency of rotational mal-alignment after reamed tibia IMnailing. This cross-sectional study was conducted at Aga khan University Hospital, Karachi, and comprised patients with tibia shaft fractures managed with IMnailing from January to December 2014. All the patients were assessed intra-operatively for rotational alignment using the knee and ankle fluoroscopic images. There were 81 patients with a mean age of 38±16.9 years. There were 64(79%) male patients. Overall the incidence of malrotation was in 20(24.7%) cases. Rotational mal-alignment is one of the preventable complications after IMnailing which can be assesed intra-operatively under fluoroscope.

VALIDITY OF THE CONNECTION INTER-LEXICAL A-SEMANTICS IN THE COGNITIVE MODEL OF PROCESSING PRAXIS

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P. G. Gómez

2011-07-01

Full Text Available Rothia Gonzalez et al. (1991, 1997 postulated a cognitive model of praxis on which changes were proposed (Cubelli et al., 2000, including the removal of the direct path between both input praxicon and output. Was suggested that to validate an inter-lexical a-semantics path (Cubelli et al., 2000 would enough to find a patientwith preserved ability for imitate familiar gestures, but with disturbances in the ability to access to the meaning of familiar gestures and alterations in ability for imitate unfamiliar gestures. The aim of this work is present two patients whose patterns ofperformance on praxis supports the existence of a pathway inter-lexical a-semantic. We evaluated two patients with Alzheimer type dementia unlikely with a battery of cognitive assessment of apraxia (Politis 2003. Both patients show alterations in test of Imitation of unfamiliar gestures and on tasks which assess semantic action objecttool watching and naming by function, with good performance on the task of imitating familiar gestures. Based on cognitive models of praxis Rothia Gonzalez et al. (1991, 1997 and Cubelli et al. (2000 is require a direct connection between both input praxicon and output to explain the performance of these patients. Of thus, the performance pattern showing both patients confirms existence of a pathway.Interlexical asemantics

Securitización en el desierto: Una respuesta al terrorismo en Malí y en Níger, 2009 - 2013.

OpenAIRE

Guerrero Escobar, Laura Catalina

2014-01-01

Este es un estudio sobre las dinámicas de seguridad en Malí durante el periodo de 2009 a 2013. La investigación busca explicar de qué manera se ha dado un proceso de securitización de los grupos insurgentes frente a la amenaza generada por la proliferación de grupos armados no estatales en el territorio comprendido entre Malí y Níger. Se toma a Níger con el ánimo de ver la existencia de un subcomplejo regional de seguridad entre este país y Malí. De esta manera se afirma que el aumento de las...

Theoretical Communities of Praxis: The University Writing Center as Cultural Contact Zone

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Monty, Randall William

2013-01-01

The fundamental purpose of "Theoretical Communities of Praxis: The University Writing Center as Cultural Contact Zone" is to investigate the situatedness of Writing Center Studies, defining it as an autonomous (sub)discipline and interdisciplinary contact zone within the larger discipline of Rhetoric and Composition. In order to meet…

Rising Mal-Employment and the Great Recession: The Growing Disconnection between Recent College Graduates and the College Labor Market

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Fogg, Neeta P.; Harrington, Paul E.

2011-01-01

This article looks at the phenomenon of mal-employment among college graduates in the United States, beginning with an overview of labor-market trends and the effects of the Great Recession on the job-market experiences of young people, including recent college graduates. It then defines "mal-employment" and examines its incidence over…

Synthesis, crystal structure and magnetic properties of [Cu(mal)(abpt ...

African Journals Online (AJOL)

Complex 1 consist of a neutral mononuclear [Cu(mal)(abpt)(H2O)] unit and water molecule of crystallization in a distorted square pyramidal coordination sphere, while complex 2 is viewed as being made up of [Cu(sq)(abpt)2] units with the squarato ligand bridging the two copper(II) cations. Variable temperature magnetic ...

MAL Overexpression Leads to Disturbed Expression of Genes That Influence Cytoskeletal Organization and Differentiation of Schwann Cells

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Daniela Schmid

2014-09-01

Full Text Available In the developing peripheral nervous system, a coordinated reciprocal signaling between Schwann cells and axons is crucial for accurate myelination. The myelin and lymphocyte protein MAL is a component of lipid rafts that is important for targeting proteins and lipids to distinct domains. MAL overexpression impedes peripheral myelinogenesis, which is evident by a delayed onset of myelination and reduced expression of the myelin protein zero (Mpz/P0 and the low-affinity neurotrophin receptor p75NTR . This study shows that MAL overexpression leads to a significant reduction of Mpz and p75NTR expression in primary mouse Schwann cell cultures, which was already evident before differentiation, implicating an effect of MAL in early Schwann cell development. Their transcription was robustly reduced, despite normal expression of essential transcription factors and receptors. Further, the cAMP response element-binding protein (CREB and phosphoinositide 3-kinase signaling pathways important for Schwann cell differentiation were correctly induced, highlighting that other so far unknown rate limiting factors do exist. We identified novel genes expressed by Schwann cells in a MAL-dependent manner in vivo and in vitro. A number of those, including S100a4, RhoU and Krt23, are implicated in cytoskeletal organization and plasma membrane dynamics. We showed that S100a4 is predominantly expressed by nonmyelinating Schwann cells, whereas RhoU was localized within myelin membranes, and Krt23 was detected in nonmyelinating as well as in myelinating Schwann cells. Their differential expression during early peripheral nerve development further underlines their possible role in influencing Schwann cell differentiation and myelination.

4. Meeting on cooling towers. From practice - for practice; 4. Kuehlturm-Tagung. Aus der Praxis - Fuer die Praxis

Energy Technology Data Exchange (ETDEWEB)

NONE

1998-09-01

The 4th Cooling Tower meeting brought into focus aspects of economic efficiency of the water cooling system, i.e. the papers analyse investment cost and operating cost taking into account environmental policy and interests. Numerous examples from practice are discussed in the papers showing how wet cooling tower design and application-specific selection of design features can influence the performance of the entire system. (orig./CB) [Deutsch] Im Mittelpunkt der 4. Kuehlturm-Tagung steht die Wirtschaftlichkeit der Wasserrueckkuehlanlage, d.h. die Betrachtung der Investitions- und Betriebskosten unter Beruecksichtigung der Belange des Umweltschutzes. Mit Beispielen aus der Praxis zeigen die Referenten, wie sich die Auslegung und Auswahl eines Nasskuehlturms auf das Betriebsergebnis der Anlage auswirken. (orig./GL)

SmartMal: a service-oriented behavioral malware detection framework for mobile devices.

Science.gov (United States)

Wang, Chao; Wu, Zhizhong; Li, Xi; Zhou, Xuehai; Wang, Aili; Hung, Patrick C K

2014-01-01

This paper presents SmartMal--a novel service-oriented behavioral malware detection framework for vehicular and mobile devices. The highlight of SmartMal is to introduce service-oriented architecture (SOA) concepts and behavior analysis into the malware detection paradigms. The proposed framework relies on client-server architecture, the client continuously extracts various features and transfers them to the server, and the server's main task is to detect anomalies using state-of-art detection algorithms. Multiple distributed servers simultaneously analyze the feature vector using various detectors and information fusion is used to concatenate the results of detectors. We also propose a cycle-based statistical approach for mobile device anomaly detection. We accomplish this by analyzing the users' regular usage patterns. Empirical results suggest that the proposed framework and novel anomaly detection algorithm are highly effective in detecting malware on Android devices.

From Research to Praxis: Empowering Trinidadian Primary School Teachers via Action Research

Science.gov (United States)

Bissessar, Charmaine S.

2015-01-01

An exponential body of extant research illustrates the symbiotic dyad action research, andragogy, reflective praxis, and transformative learning share. This paper contains a narrative review of 83 action research papers submitted to the researcher as part of the fulfilment of the Bachelor of Education degree from April 2011 to May 2013.…

Praxis Psicosocial Comunitaria en Salud, los Movimientos Sociales y la Participación Psicosocial Communitarian Praxis on Health, Social Movements and Participation

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Graciela Zaldúa

2005-12-01

Full Text Available Desde la Praxis Psicosocial comunitaria se abordan situaciones de deterioro de las condiciones de vida y aumento de la pobreza e indigencia. El enfoque crítico y de la emancipación propicia los valores de la autode-terminación, la justicia distributiva y el empoderamiento frente a la subordinación y opresión de clase, género y etnia. Los objetivos de monitorear representaciones y prácticas en escenarios comunitarios se inscribe en una Etica relacional. La metodología implementada es participativa y reflexiva, con triangulación metodológica y análisis hermenéutico. El análisis crítico de la dimensión participación, contribuye a un conocimiento subjetivo y colectivo de la realidad y posibilita la promoción de acciones que transformen las condiciones que afectan la salud y el bienestar.From the praxis social psychology we approach to the situation of deterioration of health conditions and increase of poverty and indigence The emancipatory approaches promote balance between self-determination and distributive justice and empowerment. Good society and good life are bases on mutuality and removal of oppression of gender, social systems and ethnicity. Methodology is participative and reflexive with methodological triangulation and hermeneutic analysis We propose the emphasis on participation to promote strategic monitory of needs and to facilitate promotion and prevention health.

Luminescence properties of Eu2+-doped MAl2-xSixO4-xNx (M = Ca, Sr, Ba) conversion phosphor for white LED applications

NARCIS (Netherlands)

Li, Y.Q.; With, de G.; Hintzen, H.T.J.M.

2006-01-01

Undoped and Eu-doped MAl2-xSixO4-2Nx (M = Ca, Sr, Ba) were synthesized by a solid-state reaction method at 1300 - 1400 ¿C under nitrogen-hydrogen atmosphere. The solubility of (SiN)+, in MAl2O4 was determined. Nitrogen can be incorporated into MAl2O4 by replacement of (AlO)+ by (SiN)+, whose amount

Strategie řízení třídy u studentů učitelství na praxi

OpenAIRE

Lojdová Kateřina; Škarková Lucie; Lukas Josef

2016-01-01

Cílem výzkumu je popsat strategie řízení třídy u studentů učitelství na praxi na druhém stupni českých základních škol. Právě řízení třídy je pro studenty učitelství na praxi obtížné. Nezvládnutí práce se třídou může vést až ke změně kariérní dráhy. Výzkum hloubkově interpretuje strategie řízení třídy u studentů učitelství na praxi a popisuje některé problémy, se kterými se studenti učitelství potýkají. Skrze strategie řízení třídy učitel ovlivňuje fyzický a sociální prostor školní třídy za ú...

Norms for CERAD Constructional Praxis Recall

Science.gov (United States)

Fillenbaum, Gerda G.; Burchett, Bruce M.; Unverzagt, Frederick W.; Rexroth, Daniel F.; Welsh-Bohmer, Kathleen

2012-01-01

Recall of the 4-item constructional praxis measure was a later addition to the Consortium to Establish a Registry for Alzheimer’s Disease (CERAD) neuropsychological battery. Norms for this measure, based on cognitively intact African Americans age ≥70 (Indianapolis-Ibadan Dementia Project, N=372), European American participants age ≥66 (Cache County Study of Memory, Health and Aging, N=507), and European American CERAD clinic controls age ≥50 (N=182), are presented here. Performance varied by site; by sex, education and age (African Americans in Indianapolis); education and age (Cache County European Americans; and only age (CERAD European American controls). Performance declined with increased age, within age with less education, and was poorer for women. Means, standard deviations, and percentiles are presented separately for each sample. PMID:21992077

Situação da malária na tríplice fronteira entre Brasil, Colômbia e Peru

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Paulo César Peiter

2013-12-01

Full Text Available O objetivo deste artigo é analisar a situação da vigilância da malária na tríplice fronteira entre Brasil, Colômbia e Peru. É um estudo qualitativo com aplicação de questionários em cidades da fronteira realizado em 2011. Os resultados foram analisados pela metodologia DOFA e apontaram diferenças significativas entre os sistemas de vigilância da malária na fronteira. Observou-se como debilidades a desarticulação entre atores responsáveis, a insuficiência de pessoal treinado, a alta rotatividade das equipes e a falta de médicos especialistas em malária nos hospitais locais. Verificou-se ainda o desconhecimento sobre a malária e suas formas de prevenção na população entrevistada. As fortalezas são a inserção de novos atores institucionais, a melhora da qualificação profissional, a distribuição de mosquiteiros impregnados e possibilidades de complementaridade entre os sistemas de vigilância a serem aproveitadas pela cooperação entre as equipes de saúde da fronteira, pois o controle da malária só pode ter sucesso tomando-se esta região em seu conjunto.

Causas mal definidas de morte e óbitos sem assistência Ill-defined causes of death and unattended deaths, Brazil, 2003

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Augusto Hasiak Santo

2008-02-01

Full Text Available OBJETIVOS: Este trabalho estuda a distribuição dos óbitos por causas mal definidas no Brasil, no ano de 2003, entre as quais identifica a proporção de mortes sem assistência. MÉTODOS: Os dados provieram do Sistema de Informações Sobre Mortalidade, coordenado pelo Ministério da Saúde. As causas mal definidas de morte compreenderam as incluídas no "Capítulo XVIII - Sintomas, sinais e achados anormais de exames clínicos e de laboratório não classificados em outra parte" da Classificação Estatística Internacional de Doenças e Problemas Relacionados à Saúde, décima revisão, capítulo este no qual a categoria R98 identificava a "morte sem assistência". RESULTADOS: No Brasil, em 2003, a causa básica de 13,3% dos óbitos foi identificada como mal definida, sendo que as proporções maiores ocorreram nas Regiões Nordeste e Norte. Do total de causas mal definidas no país, 53,3% corresponderam a mortes sem assistência, proporção esta que superou 70% nos Estados do Maranhão, Piauí, Rio Grande do Norte, Pernambuco, Bahia, Paraíba e Alagoas. CONCLUSÃO: Dada a estrutura descentralizada para o levantamento dos óbitos no país, identifica-se a maior responsabilidade dos municípios e, em seguida, dos Estados para o aprimoramento da qualidade das estatísticas de mortalidade.BACKGROUND: We studied the distribution of deaths from ill-defined causes that occurred in Brazil during 2003, from which was identified the proportion of unattended deaths. METHODS: Data were obtained from the Mortality Information System, coordinated by the Ministry of Health. Causes of death included in "Chapter XVIII - Symptoms, signs and abnormal clinical and laboratory findings, not classified elsewhere" of the International Statistical Classification of Diseases and Related Health Problems, tenth revision, were considered ill-defined, among which the category R98 identified "unattended deaths". RESULTS: In Brazil during 2003 the underlying causes of

Association of Mal/TIRAP S180L variant polymorphism with decreased infection risk in patients with advanced HIV-1 infection.

NARCIS (Netherlands)

Papadopoulos, A.I.; Ferwerda, B.; Antoniadou, A.; Sakka, V.; Galani, L.; Kavatha, D.; Panagopoulos, P.; Poulakou, G.; Protopapas, K.; Meer, J.W.M. van der; Netea, M.G.; Giamarellos-Bourboulis, E.J.

2012-01-01

OBJECTIVES: MyD88 adaptor-like (Mal/TIRAP) is an adaptor protein bridging activation of Toll-like receptors 2 and 4 after stimulation by exogenous and endogenous ligands. We investigated the association between the presence of the S180L SNP of Mal and the risk of severe infection in individuals with

Disambiguating Praxis from Practice in Natural Resource Management: A Practical Space for Enhancing Experiential Learning in the Eastern Coast of Tanzania

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Sabai Daniel

2017-03-01

Full Text Available It is evident that practice and praxis have significantly contributed to knowledge generation in the Tanzanian coastal belt, especially where Integrated Coastal Management (ICM programmes have been adopted and practiced such as Tanga, Dar es Salaam, Mtwara, Lindi, and the Coastal region (KICAMP, 2001; NICEMS, 2003. In spite of such learning evidences, users of generated natural resource data in the coastal area tend to employ practice and praxis interchangeably, conflating the two concepts together; leading to a situation where one may hardly ascribe generated knowledge appropriately to contexts that favour occurrence of each of the two constructs. The paper adopts ethnographic approach in a defined coastal case study to examine contexts and situations that signals “conflationˮ and it employs examples that may help readers of the article to disambiguate praxis from practice.

La Justificación de la Presencia del Mal en el Mundo desde la Estética Agustiniana

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David Ezequiel Téllez Maqueo

2016-07-01

Full Text Available La posibilidad de establecer una conciliación entre Dios como principio absoluto de bondad, y el mal presente en la realidad en sus más diversas manifestaciones (miseria, guerras, enfermedad, ignorancia, etc., ha sido una preocupación constante en la historia del pensamiento occidental. Si Dios existe, ¿cómo puede suceder que exista mal en el mundo? Para dar una respuesta racional satisfactoria se han planteado diversas respuestas. Pero Agustin de Hipona representa la primera teodicea dominante de la historia occidental, por lo que el conocimiento de su postura ante este problema es digno de interés. Para ello, el objetivo de estas líneas es triple: 1 establecer en qué consiste la solución estética de san Agustin al problema del mal, II señalar algunas de las críticas más conocidas que ha recibido en el siglo XX, y III afirmar que la solución agustiniana puede seguir siendo base de una teodicea capaz de hacer compatible la existencia de Dios y el mal en el mundo, tras la valoración de las distintas posturas críticas que ha recibido.

When Cathy Was a Little Girl: The Healing "Praxis" of Tarot Images

Science.gov (United States)

Semetsky, Inna

2010-01-01

This paper is a sequel to an earlier article that presented an argument for Tarot symbolic system functioning as a "techne" that can serve as a valuable educational aid. The present paper shifts the focus from "techne" to "praxis" as a practical art of interpreting images and creating imaginative narratives in the context of counselling and…

Grounding the past : the praxis of participatory archaeology in the Mixteca Alta, Oaxaca, Mexico

NARCIS (Netherlands)

Geurds, Alexander

2007-01-01

"Grounding the Past" addresses archaeological field praxis and its role in the political present of Santiago Tilantongo and Santiago Apoala, two communities in the Mixteca Alta region of Oaxaca, Mexico. Efforts to involve local stakeholder communities in archaeology have become an important issue

Specialization of the left supramarginal gyrus for hand-independent praxis representation is not related to hand dominance

Science.gov (United States)

Króliczak, Gregory; Piper, Brian J.; Frey, Scott H.

2016-01-01

Data from focal brain injury and functional neuroimaging studies implicate a distributed network of parieto-fronto-temporal areas in the human left cerebral hemisphere as playing distinct roles in the representation of meaningful actions (praxis). Because these data come primarily from right-handed individuals, the relationship between left cerebral specialization for praxis representation and hand dominance remains unclear. We used functional magnetic resonance imaging (fMRI) to evaluate the hypothesis that strongly left-handed (right hemisphere motor dominant) adults also exhibit this left cerebral specialization. Participants planned familiar actions for subsequent performance with the left or right hand in response to transitive (e.g., “pounding”) or intransitive (e.g. “waving”) action words. In linguistic control trials, cues denoted non-physical actions (e.g., “believing”). Action planning was associated with significant, exclusively left-lateralized and extensive increases of activity in the supramarginal gyrus (SMg), and more focal modulations in the left caudal middle temporal gyrus (cMTg). This activity was hand- and gesture-independent, i.e., unaffected by the hand involved in subsequent action performance, and the type of gesture (i.e., transitive or intransitive). Compared directly with right-handers, left-handers exhibited greater involvement of the right angular gyrus (ANg) and dorsal premotor cortex (dPMC), which is indicative of a less asymmetric functional architecture for praxis representation. We therefore conclude that the organization of mechanisms involved in planning familiar actions is influenced by one’s motor dominance. However, independent of hand dominance, the left SMg and cMTg are specialized for ideomotor transformations—the integration of conceptual knowledge and motor representations into meaningful actions. These findings support the view that higher-order praxis representation and lower-level motor dominance rely

A formação humana e a incapacidade de pensar: considerações sobre o problema do mal em Hannah Arendt

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Marcos Alexandre Alves

2017-08-01

Full Text Available Este artigo pretende apresentar o tema da formação humana conectado à incapacidade de pensar, tecendo considerações sobre o problema do mal no pensamento de Hannah Arendt. A autora é conhecida como pensadora da política que concentrou atenção especial ao problema do mal que assolou o mundo na primeira metade do século XX. A partir da análise de Origens do Totalitarismo, de 1951, e de Eichmann em Jerusalém: um relato sobre a banalidade do mal, de 1963, pretende-se refletir acerca dos mecanismos que produzem o adormecimento da capacidade de pensar frente à necessidade da formação humana. A partir dessa análise, se perceberá que o problema do mal assume um viés radical, uma possibilidade de destruição completa do humano. Na análise do caso Eichmann, Arendt percebeu que o réu agia banalmente, manifestando sua incapacidade de pensar, o que tornou possível a normalização da insensibilidade frente o diferente. Portanto, a banalidade do mal implica na incapacidade de pensar, uma ameaça sempre constante à formação humana

Urban (revolutions. Radical rhetoric versus reformist praxis

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Przemysław Pluciński

2013-01-01

Full Text Available The paper deals with the idea of ??the right to the city (RTTC, one ofthe leading ideologies of contemporary emancipatory politics. It also focuses on socialactors (mainly Polish urban social movements as the RTTC users and deals with theproblem how urban activists use the idea in everyday political praxis. The right to thecity is analysed with respect to the Laclau’s notion of an “empty signifier”, that is, as anelement which depends on the interpretation put on it in the pragmatics of social struggles.Furthermore, the article examines the fact of consistent functionalization of theRTTC idea. The initially Marxian concept of revolutionary origins is now becomingincreasingly reformist and is being used mainly as a popular political label.

Education for Sustainable Development in Higher Education: Evaluating Coherence between Theory and "Praxis"

Science.gov (United States)

Amador, Filomena; Martinho, Ana Paula; Bacelar-Nicolau, Paula; Caeiro, Sandra; Oliveira, Carla Padrel

2015-01-01

Universities are an important part of the process of change taking place in society. However, this is often overshadowed by these institutions giving priority to technocratic models in the relationship between science and society. In this context, according to Habermas, theories can serve to clarify practical questions and guide praxis into the…

Conunents on Wagar' s "Toward a Praxis of World Integration"

OpenAIRE

Richard Schauffler

2015-01-01

Warren Wagar's 1995 ASA paper is an attempt to articulate a view of global political praxis culminating in a "democratic, liberal, and socialist world commonwealth." This is an admirable idea, but do the ideas in that paper get us closer to its realization--I think not. As I will argue below, Wagar's paper is nothing more than the Third International writ large, a polemic on organizational form ironically tied to a Eurocentric Second International view of the world that appears to ignore the ...

O problema do mal: a interpretação de São Boaventura = The problem of evil: the interpretation of Saint Bonaventure

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Vasconcellos, Manoel

2012-01-01

Full Text Available Tomando, especialmente, o Breviloquium como guia, podemos entender o modo como São Boaventura analisa o problema do mal e sua relação com o pecado. O homem foi criado bom, para viver num mundo bom. Com o pecado, rompeu com o projeto divino, instaurando o mal no mundo. Deus, o princípio primeiro e perfeitíssimo, contudo, não deixa de levar à perfeição sua obra, razão pela qual vem ao encontro do homem para vencer o pecado e o mal. Numa reflexão em que Filosofia e Teologia se entrecruzam, Boaventura, ao discorrer sobre a origem, transmissão e superação do mal, deixa transparecer o papel singular e afirmativo do homem, pois, apesar do pecado, não perdeu sua atração natural às virtudes, sendo capaz de agir bem

Understanding Academic Work as Practical Activity--and Preparing (Business-School) Academics for Praxis?

Science.gov (United States)

Rasanen, Keijo

2009-01-01

This text suggests a way of framing academic work and outlines a design for a preparatory event based on this understanding. It conceives academic work as "practical activity" and potential "praxis" in emergence by focusing on four issues: how can I do this work (tactical stance), what can I accomplish and achieve in it…

The Mastery Matrix for Integration Praxis: The development of a rubric for integration practice in addressing weight-related public health problems.

Science.gov (United States)

Berge, Jerica M; Adamek, Margaret; Caspi, Caitlin; Grannon, Katherine Y; Loth, Katie A; Trofholz, Amanda; Nanney, Marilyn S

2018-06-01

In response to the limitations of siloed weight-related intervention approaches, scholars have called for greater integration that is intentional, strategic, and thoughtful between researchers, health care clinicians, community members, and policy makers as a way to more effectively address weight and weight-related (e.g., obesity, diabetes, cardiovascular disease, cancer) public health problems. The Mastery Matrix for Integration Praxis was developed by the Healthy Eating and Activity across the Lifespan (HEAL) team in 2017 to advance the science and praxis of integration across the domains of research, clinical practice, community, and policy to address weight-related public health problems. Integrator functions were identified and developmental stages were created to generate a rubric for measuring mastery of integration. Creating a means to systematically define and evaluate integration praxis and expertise will allow for more individuals and teams to master integration in order to work towards promoting a culture of health. Copyright © 2018 Elsevier Inc. All rights reserved.

Extrametodical truth and ontology of the praxis: The mediator rationality of the phronesis

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Gaetano Chiurazzi

2016-05-01

Full Text Available Gadamer’s vindication of the extra-methodical feature of truth in the human sciences put forward in Truth and Method does not mean a mere refusal of method: rather, it arises from the awareness that there are truths which are not reducible to the conditions of repeatability and commensurability set up by methodical thinking. In fact, the truths of the human sciences refer to the ontological dimension of the contingent and the accidental, i.e. to the dimension of the historical. In this essay I aim at highlighting this ontological dimension, which for Aristotle is eminently that of the praxis and of human action. I will show that such an ontology is a consequence of the logical and ontological discussions which crisscrossed Greek thought after the discovery of the incommensurable magnitudes. The ontology of praxis is an ontology which takes into account the “irrationality” represented by the contingent, the accidental, to which a new form of rationality corresponds: that of phrónesis. Phrónesis is in fact not a commensurative but a mediative rationality

THEORIA, PRAXIS, POIESIS: A CONTINUUM SCHEME

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Ayla Ayyıldız Potur

2011-07-01

Full Text Available The present age provides that the new production technologies are in a continuous experimental production in terms of both quantitative and rapidness criteria. Thinking and testing speed comes closer with these experiences. Knowledge management systems begin to be more important when knowledge and experience generated in the virtual environment with the increased processing of information exceeds the individual’s processing capacity. The continuous transformation process with new technologies, organizational models and cross-distance communication, installs a variety of responsibilities to both academic and professional environment. In this study, based on Aristotle’s fundamental “theory” (theoria, “practice” (praxis, “poetik” (poiesis, parser for disciplinary point of view will be discussed related to “thinking”, “doing” and “creating” actions. The different nature of design disciplines in relation to theoretical knowledge, practical knowledge, and creative knowledge will also be discussed.

Mal de Meleda: A Report of Two Cases In One Family

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M.Kantor

2006-08-01

Full Text Available Mal de Meleda is a rare autosomal recessive skin disorder, characterized by transgressive palmoplantar keratoderma, lichenoid skin lesions, perioral erythema, brachydactyly and nail abnormalities. We are reporting two cases of a clinically typical disease in a family. No consanguineous relationship between the parents was known and cases could not be detected in three generations of the patient's family.

De culpable a perseguido: Baudelaire y el proceso de Las Flores del Mal

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Juan Zapata

2018-01-01

Full Text Available ¿Cómo el poeta de Las Flores del Mal pasó de ser un escritor proscrito, y en consecuencia sospechoso, al autor perseguido e incomprendido que ha inmortalizado la historia literaria? ¿Cómo Baudelaire pudo desviar a su favor una circunstancia que, a primera  vista, era desafortunada? Baudelaire supo utilizar el escándalo que provocó la publicación de Las Flores del Mal para promover su figura pública. Un análisis de las posturas discursivas desplegadas por Baudelaire antes, durante y después del proceso nos permitirá comprender mejor la inversión que el poeta hace de su condenación, al transformar la sanción penal y moral, así como la exclusión a la que esta conduce, en un signo de su grandeza y de su gloria póstuma.

The Continuous Quality Improvement Book Club: Developing a Book Club to Promote Praxis

Science.gov (United States)

Lyons, Becky; Ray, Chris

2014-01-01

This article poses a model for developing a book club to promote praxis. This model is built upon a basic four step framework for developing book clubs and includes specific recommendations to focus the book club on reflection of theory and how to incorporate it into practice. This model will be used to start a book club examining Continuous…

Environmental justice in Scotland: policy, pedagogy and praxis

International Nuclear Information System (INIS)

Scandrett, Eurig

2007-01-01

In the first decade of Scottish devolution, environmental justice became a significant component of environmental policy for the Scottish Executive, especially under First Minister Jack McConnell. This paper analyses how a discourse developed within policy narratives which separated environmental justice from economic growth and the interests of capital. In particular, it explores the role which research has played in justifying this discourse. By contrast, an alternative discourse has developed through reflexive and dialogical research associated with the praxis of the environmental organization Friends of the Earth Scotland. This alternative discourse is embedded in the embryonic environmental justice movement in Scotland, and identifies environmental justice as a social conflict which exposes negative externalities at the heart of economic development

Environmental justice in Scotland: policy, pedagogy and praxis

Energy Technology Data Exchange (ETDEWEB)

Scandrett, Eurig [Queen Margaret University, Edinburgh (United Kingdom)

2007-10-15

In the first decade of Scottish devolution, environmental justice became a significant component of environmental policy for the Scottish Executive, especially under First Minister Jack McConnell. This paper analyses how a discourse developed within policy narratives which separated environmental justice from economic growth and the interests of capital. In particular, it explores the role which research has played in justifying this discourse. By contrast, an alternative discourse has developed through reflexive and dialogical research associated with the praxis of the environmental organization Friends of the Earth Scotland. This alternative discourse is embedded in the embryonic environmental justice movement in Scotland, and identifies environmental justice as a social conflict which exposes negative externalities at the heart of economic development.

Efficacy and safety of 4 months of sublingual immunotherapy with recombinant Mal d 1 and Bet v 1 in patients with birch pollen-related apple allergy.

Science.gov (United States)

Kinaciyan, Tamar; Nagl, Birgit; Faustmann, Sandra; Frommlet, Florian; Kopp, Stephan; Wolkersdorfer, Martin; Wöhrl, Stefan; Bastl, Katharina; Huber, Hans; Berger, Uwe; Bohle, Barbara

2018-03-01

Birch pollen-related apple allergy is among the most prevalent food allergies in adolescent/adult subjects and mainly results from sensitization to the major birch pollen allergen Bet v 1 and subsequent cross-reaction with the apple protein Mal d 1. However, specific immunotherapy with birch pollen has inconsistent effects on apple allergy. We sought to compare the safety and efficacy of sublingual immunotherapy (SLIT) with 2 formulations containing either rMal d 1 or rBet v 1 on birch pollen-related apple allergy. Sixty participants with birch pollen-related apple allergy were randomized to daily sublingual application of placebo (n = 20) or 25 μg of rMal d 1 (n = 20) or rBet v 1 (n = 20) for 16 weeks. Adverse events were regularly recorded. Sublingual challenges with standardized doses of rMal d 1, skin prick tests with recombinant allergens, and measurements of allergen-specific IgE and IgG 4 antibodies were performed before and after treatment. Both formulations caused comparable, mainly local adverse events. No systemic reactions occurred. Compared with the placebo and rBet v 1-treated groups, SLIT with rMal d 1 reduced rMal d 1-induced oral symptoms (P = .001 and P = .038) accompanied by longitudinally reduced rMal d 1-specific cutaneous reactions (P = .022) and enhanced IgG 4 /IgE ratios (P = .012). SLIT with rBet v 1 neither improved the clinical reactivity to rMal d 1 nor enhanced rMal d 1-specific IgG 4 /IgE ratios. Participants receiving placebo showed no allergen-specific changes. Sublingual treatment with a recombinant food allergen was safe and clinically effective, as determined by using standardized challenges. We present a promising approach for the effective treatment of birch pollen-related apple allergy. Copyright © 2017 American Academy of Allergy, Asthma & Immunology. Published by Elsevier Inc. All rights reserved.

Ethics in Research on Learning: Dialectics of Praxis and Praxeology

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SungWon Hwang

2005-01-01

Full Text Available Qualitative social research designed to develop ways of understanding and explaining lived experience of human beings is a reflexive human endeavor. It is reflexive in that as researchers attempt to better understand their participants, they also come to better understand themselves. Consequently, research ethics itself becomes an ethical project, for it pertains to participant and researcher at the same time: Both are subjects, knower and known. Particularly in case of research on learning, reflexivity arises from the fact that the research itself constitutes learning about learning. How is ethics in research on learning reflexive of, in its praxis and praxeology, ongoing events and changes of the human learning? In this study, from our experience of conducting a project designed to inquire into "learning in unfamiliar environments," we develop pertinent ethical issues through a dialectical process—not unlike that used by G.W.F. HEGEL in Phenomenology of Spirit—grounded in our lived experience and developed in three theoretical claims concerning a praxeology of ethics. First, ethics is an ongoing historical event; second, ethics is based on the communicative praxis of material bodies; and third, ethics involves the creation of new communicative configurations. We conclude that ethics is grounded in a fundamental answerability of human beings for their actions, which requires communicative action that itself is a dialectical process in opening up possibilities for acting in an answerable manner. URN: urn:nbn:de:0114-fqs0501198

Savoir gérer le mal

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Michel Maffesoli

2015-09-01

Full Text Available Le sens commun, conservatoire immémorial de la sagesse humaine « sait », de savoir incorporé, que le mal, l’ombre, la mort, la douleur sont des caractéristiques essentielles de l’existence en son entièreté. Dès lors les créatures quelles qu’elles soient, sont des manifestations de la vie et, dès lors, méritent une attitude « compassionnelle », fraternelle, parce qu’ensemble elles constituent le flux vital. C’est ainsi que l’on peut comprendre l’utilité sociale de ces divers « mondes intermédiaires » que sont les croyances, religieuses ou philosophiques, au « double », au « daimon », aux esprits et autres figures tutélaires ou effrayantes. Elles aident à vivre, au jour le jour, la souffrance en la communalisant.

Retardo no crescimento intrauterino, baixo peso ao nascer e prematuridade em recém-nascidos de grávidas com malária, na Colômbia

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Alberto Tobón-Castaño

2011-06-01

Full Text Available INTRODUÇÃO: É frequente a associação da malária com complicações como prematuridade, retardo no crescimento intrauterino, baixo peso ao nascer e mortalidade infantil, efeitos pouco estudados em áreas hipoendêmicas para malaria. O objetivo deste estudo foi analisar a relação da malária gestacional com estes efeitos em recém-nascidosnuma região endêmica para malária na Colômbia, entre 1993 e 2007. MÉTODOS: Foram estudadas as características em 1.716 recém-nascidos num estudo de coorte. Fez-se seguimento em 394 gestantes com malária (27% por Plasmodium falciparum e 73% por P. vivax e 1.322 sem malária. RESULTADOS: Foi encontrada uma relação entre a exposição à malária na gestação e o risco maior de baixo peso ao nascer (RR = 1,37; 1,03-1,83, assim como estatura baixa (RR = 1,52; 1,25-1,85, retardo no crescimento intrauterino (RR = 1,29; 1,0-1,66 e prematuridade (RR = 1,68; 1,3-2,17. A frequência de nascimentos prematuros foi maior nas mães com malária por P. falciparum (77% que aquelas com P. vivax (RR = 1,77; IC 95%: 1,2-2,6. CONCLUSÕES: O baixo peso ao nascer e o retardo no crescimento foi associado com malária na gestação na Colômbia. A infecção por P. vivax foi relacionada com efeitos adversos sobre o recém-nascido, de modo semelhante em relação ao P. falciparum.

Reflexion in der Praxis der Sozialen Arbeit: Informeller Austausch versus methodengeleitete Reflexion

OpenAIRE

Hofer, Andi; Pivarci, Pavol

2010-01-01

Die qualitative Studie «Reflexion in der Praxis der Sozialen Arbeit» basiert auf der Annahme, dass ein unterschiedliches Verständnis zu einer unterschiedlichen Umsetzung der Reflexion führt. Reflexion ist jedoch ein gefordertes Qualitätskriterium der Sozialen Arbeit. In der relevanten Literatur ist Reflexion ein Bestandteil des methodischen Handelns und wird als Evaluation oder reflexive Aufgabenbearbeitung definiert, wobei sie durch individuelle und institutionelle Faktoren wechselseitig bed...

Une localisation exceptionnelle de la tuberculose vertébrale Mal de Pott sous-occipital

Science.gov (United States)

Yahyaoui, Sana; Majdoub, Senda; Zaghouani, Houneida; Fradj, Hosni Ben; Bakir, Dejla; Bouajina, Elyes; Kraiem, Chakib

2013-01-01

Le mal de Pott est la forme la plus commune de la tuberculose osseuse touchant essentiellement le rachis dorso-lombaire. La localisation sous-occipitale reste exceptionnelle. Le diagnostic de cette entité est le plus souvent tardif ce qui expose à des complications graves. Les radiographies standard ne sont parlantes qu’à un stade tardif de la maladie, d'où l'intérêt de l'imagerie moderne notamment la tomodensitométrie (TDM) et l'imagerie par résonance magnétique (IRM) qui permettent un diagnostic précoce. Nous rapportons un nouveau cas de tuberculose sous-occipitale. Le diagnostic était posé sur l'imagerie en coupe et confirmé histologiquement à la biopsie transorale. Sont rappelés les aspects en imagerie de cette localisation particulière du mal de Pott. PMID:23819005

Structure of the conserved hypothetical protein MAL13P1.257 from Plasmodium falciparum

International Nuclear Information System (INIS)

Holmes, Margaret A.; Buckner, Frederick S.; Van Voorhis, Wesley C.; Mehlin, Christopher; Boni, Erica; Earnest, Thomas N.; DeTitta, George; Luft, Joseph; Lauricella, Angela; Anderson, Lori; Kalyuzhniy, Oleksandr; Zucker, Frank; Schoenfeld, Lori W.; Hol, Wim G. J.; Merritt, Ethan A.

2006-01-01

The crystal structure of a conserved hypothetical protein, MAL13P1.257 from P. falciparum, has been determined at 2.17 Å resolution. The structure represents a new protein fold and is the first structural representative for Pfam sequence family PF05907. The structure of a conserved hypothetical protein, PlasmoDB sequence MAL13P1.257 from Plasmodium falciparum, Pfam sequence family PF05907, has been determined as part of the structural genomics effort of the Structural Genomics of Pathogenic Protozoa consortium. The structure was determined by multiple-wavelength anomalous dispersion at 2.17 Å resolution. The structure is almost entirely β-sheet; it consists of 15 β-strands and one short 3 10 -helix and represents a new protein fold. The packing of the two monomers in the asymmetric unit indicates that the biological unit may be a dimer.

Aristotle's Rhetoric, Hitler's Program, and the Ideological Problem of Praxis, Power, and Professional Discourse.

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Katz, Steven B.

1993-01-01

Examines Hitler's use of propaganda to construct praxis and define phronesis in Nazi Germany in terms of the rational but open-ended nature of Aristotle's political-ethical thought. Examines the failure of professional discourse surrounding the siting of a low-level nuclear waste facility to create a persuasive reality and yet ideologically…

Light fractionation increases the efficacy of ALA-PDT but not of MAL-PDT: What is the role of (vascular) endothelial cells?

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de Bruijn, H. S.; de Vijlder, H. C.; de Haas, E. R. M.; van der Ploeg-van den Heuvel, A.; Kruijt, B.; Poel-Dirks, D.; Sterenborg, H. J. C. M.; ten Hagen, T. L. M.; Robinson, D. J.

2009-06-01

Photodynamic therapy (PDT) using protoporpyrin IX (PpIX) precursors like 5-aminolevulinic acid (ALA) or methyl-aminolevulinate (MAL) has shown to be effective in the treatment of various skin diseases. Using ALA we have shown in numerous studies a significantly improved efficacy by applying light fractionation with a long dark interval. In contrast, in the hairless mouse model, the PDT efficacy using MAL is unaffected by adopting this approach. More acute edema is found after ALA-PDT suggesting a difference in response of endothelial cells to PDT. To investigate the role of endothelial cells, cryo-sections of hairless mouse skin after 4 hours of topical MAL or ALA application were stained with a fluorescent endothelial cell marker (CD31). Co-localization of this marker with the PpIX fluorescence was performed using the spectral imaging function of the confocal microscope. We have also used intra-vital confocal microscopy to image the PpIX fluorescence distribution in correlation with the vasculature of live mouse skin. Our results show PpIX fluorescence at depth in cryo-sections of mouse skin after 4 hours of topical application. Co-localization has shown to be difficult due to the changes in tissue organization caused by the staining procedure. As expected we found high PpIX fluorescence levels in the epidermis after both MAL and ALA application using intra-vital microscopy. After ALA application more PpIX fluorescence was found deep in the dermal layer of the skin than after MAL. Furthermore we detected localized fluorescence in unidentified structures that could not be correlated to blood vessels or nerves.

"Makin' Somethin' Outta Little-to-Nufin'': Racism, Revision and Rotating Records--The Hip-Hop DJ in Composition Praxis

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Craig, Todd

2015-01-01

Prompted by a moment in the classroom in which the DJ becomes integral for the writing instructor, this article looks at how the hip-hop DJ and hip-hop DJ/Producer become the intrinsic examples for first-year college writing students to think about how they conduct revision in their writing. After a review of two seminal hip-hop books and other…

[Eugen Helimski, Urlike Kahrs. Nordselkupisches Wörterbuch von F. G. Mal'cev (1903)] / Ago Künnap

Index Scriptorium Estoniae

Künnap, Ago, 1941-

2003-01-01

Raamatust: Helimski, Eugen, Kahrs, Urlike. Nordselkupisches Wörterbuch von F. G. Mal'cev (1903). Hamburg, 2001. (Hamburger Sibirische und Finnisch-Ugrische Materialen / Habent Sua Fata Manuscripts; 1)

GENEALOGÍA, VIDA, PRAXIS - ACERCA DE LOS DESAFÍOS CONCEPTUALES DE LA “NUDA VIDA”

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Marcelo Córdoba

2010-12-01

Full Text Available Resumen El propósito de este artículo es desarrollar una evaluación polémica de las premisas y las conclusiones que Giorgio Agamben despliega en la serie Homo Sacer. Específicamente, esta polémica se concentrará en el abusivo empleo de la genealogía foucaultiana. El artículo comienza con una exposición sintética de las tesis centrales de Agamben. A continuación, hace referencia a las debilidades constitutivas del paradigma estructuralista para pensar el cuerpo. Estas debilidades habrían sido superadas por la teoría postestructuralista de Deleuze, quien concibió un modelo dinámico del cuerpo y del deseo, llegando a postularlos como el principio mismo de la praxis y la historicidad humanas. Este principio es asumido por el “materialismo antidialéctico” de Toni Negri, presentado como una filosofía de la praxis adecuada a un contexto de dominación biopolítica planetaria. Pero si Negri restituye la historicidad de la condición humana, su concepción totalizadora de “biopolítica” impide pensar un criterio operativo de crítica social. El artículo concluye exponiendo la noción de “crítica” que Foucault sugiriera hacia el final de su producción; a esta luz, explicita las razones que vuelven a la investigación de Agamben incompatible, no sólo con la propuesta de Foucault, sino con cualquier forma de crítica y praxis sociales de liberación. 

MAL Is a Regulator of the Recruitment of Myelin Protein PLP to Membrane Microdomains

NARCIS (Netherlands)

Bijlard, Marjolein; de Jonge, Jenny C.; Klunder, Bert; Nomden, Anita; Hoekstra, Dick; Baron, Wia

2016-01-01

In oligodendrocytes (OLGs), an indirect, transcytotic pathway is mediating transport of de novo synthesized PLP, a major myelin specific protein, from the apical-like plasma membrane to the specialized basolateral-like myelin membrane to prevent its premature compaction. MAL is a well-known

Ubuntu-Praxis: Re-Modelling the Balanced Scorecard Model at a University, an Afrocentric Perspective

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Ndoda, Gladys Ruvimbo; Sikwila, Mike Nyamazana

2014-01-01

The authors design the innovation and learning perspective of the Balanced Scorecard (BSC) of "Ubuntu and client service charter nexus." This article borrows and advances the research carried out by Khomba, Vermaak and Gouws (2011). The point of departure is on praxis of ubuntu/unhu as a holistic approach in the re-modelling of the BSC…

Le problème du mal dans le Guide des Perplexes et son arrière-plan talmudique

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Costa, José

2010-12-01

Full Text Available At first sight, the question of evil is regarded in the Guide for the Perplexed in a paradoxical manner. Thus, in Guide I, 2, Maimonides examines the notions of good and evil as subjective evaluations possessing neither the rigour not the exactness of the notions of true and false. However, the question of evil occupies an essential place in the Guide, as various modern authors have shown. This question is important to Maimonides because he is, in this respect, the heir of the rabbinic tradition and his conception of evil is largely based on an interaction with the Talmudic and Midrašic texts. Therefore, we would like to review thirty-nine rabbinic ‘quotes’ which appear in chapters 8 to 24 in the third part of the Guide and deal with the origin of evil, the meaning of suffering and the evil inclination. Maimonides reappropriates the midrašim that are susceptible of being in agreement with his rationalist positions and also quotes some rabbinic traditions that are too close to mu ͑tazilism, undoubtedly aware of the more profound resemblance that exists between the rabbinic and mu ͑tazilite doctrines of evil and retribution.A primera vista, el problema del mal es abordado en la Guía de Perplejos de manera paradójica. Para Maimónides, las nociones de bien y mal son subjetivas y no resultan ni rigorosas ni exactas, a la inversa de las nociones de verdad y falsedad (Guía I, 2. Sin embargo, el problema del mal es muy importante en la Guía, como lo demostraran varios autores. Maimónides es el heredero de la tradición rabínica y existe en la Guía una interacción entre la filosofia de Maimónides y los textos talmúdicos y midrásicos. Es particularmente el caso de las treinta y nueve citas rabínicas de la Guía II, 8-24, que tratan del origen del mal, del significado del sufrimiento y de la inclinación al mal. Maimónides cita los midrašim que concuerdan con sus posiciones racionalistas y evoca también algunas tradiciones rab

Arendt, Eichmann y la banalidad del mal

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López, Marina

2010-04-01

Full Text Available In this text I describe the characteristics that Hannah Arendt attributes to the SS agents through the figure of Eichmann, during the German Nazi regime of the 20th century. According to this characterization, I intend to show, on the one hand, that there is not a break in Arendt’s thought on evil, i.e. from The Origins of Totalitarianism to Eichmann in Jerusalem: a report on the banality of evil, but a continuous line of thought. And, on the other hand, I try to follow the clues that Arendt gives concerning the “banality” that defines the behavior of individuals such as Eichmann. Both premises will permit me to point out what, in my understanding, the banalization of humanity implies, not only in the context of the Jewish Holocaust, but in each of the societies in which the elimination of spontaneity is a reality.

En el texto se describen las características que Hannah Arendt, a través de la figura de Eichmann, atribuye a los agentes SS durante el régimen nazi alemán de mediados del siglo XX. Con la caracterización se persigue mostrar, en principio, que no hay una ruptura en el pensamiento de Hannah Arendt respecto a su manera de considerar el mal, desde Los orígenes del Totalitarismo hasta Eichmann en Jerusalén, un estudio sobre la banalidad del mal, sino una continuidad y, por otra parte, seguir las pistas que Arendt propone en torno a la “banalidad” que define el comportamiento de individuos como Eichmann. Ambas premisas nos permitirán poner de relieve lo que, a nuestro parecer, implica la banalización de la humanidad no sólo en el contexto del Holocausto judío, sino en cada una de las sociedades en las que la eliminación de la espontaneidad es una realidad.

Differences in praxis performance and receptive language during fingerspelling between deaf children with and without autism spectrum disorder.

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Bhat, Anjana N; Srinivasan, Sudha M; Woxholdt, Colleen; Shield, Aaron

2018-04-01

Children with autism spectrum disorder present with a variety of social communication deficits such as atypicalities in social gaze and verbal and non-verbal communication delays as well as perceptuo-motor deficits like motor incoordination and dyspraxia. In this study, we had the unique opportunity to study praxis performance in deaf children with and without autism spectrum disorder in a fingerspelling context using American Sign Language. A total of 11 deaf children with autism spectrum disorder and 11 typically developing deaf children aged between 5 and 14 years completed a fingerspelling task. Children were asked to fingerspell 15 different words shown on an iPad. We coded various praxis errors and fingerspelling time. The deaf children with autism spectrum disorder had greater errors in pace, sequence precision, accuracy, and body part use and also took longer to fingerspell each word. Additionally, the deaf children with autism spectrum disorder had poor receptive language skills and this strongly correlated with their praxis performance and autism severity. These findings extend the evidence for dyspraxia in hearing children with autism spectrum disorder to deaf children with autism spectrum disorder. Poor sign language production in children with autism spectrum disorder may contribute to their poor gestural learning/comprehension and vice versa. Our findings have therapeutic implications for children with autism spectrum disorder when teaching sign language.

Praxis development in relation to gang conflicts in Copenhagen, Denmark

DEFF Research Database (Denmark)

Mørck, Line Lerche; Hussain, Khaled; Møller-Andersen, Camilla

2013-01-01

The primary question addressed in this article is how to understand and produce praxis development in the complex and contentious field of street communities of young marginalized men, an area highlighted almost on a daily basis in the Danish media under headlines with terms such as ‘foreigner...... othering of young minority men since the late 1990s, to other societal changes escalating ‘gang-conflicts’ to ‘gang-war’. The article examines how these changes produce new dynamics, tensions and dimensions of binary thinking, which in turn creates new dilemmas in the everyday lives of the people involved...

Emancipatory Nursing Praxis: A Theory of Social Justice in Nursing.

Science.gov (United States)

Walter, Robin R

Emancipatory nursing praxis (ENP) is a middle-range nursing theory of social justice developed from an international, grounded theory study of the critical factors influencing nurses' perceptions of their role in social justice. The ENPs implementing processes (becoming, awakening, engaging, and transforming) and 2 conditional contexts (relational and reflexive) provide an in-depth understanding of the transformative learning process that determines nurse engagement in social justice. Interpretive findings include the voice of Privilege primarily informed ENP theory, the lack of nursing educational and organizational support in social justice role development, and the advocate role should expand to include the role of an ally.

Kärnproblem : opinionsbildning i kärnavfallsdiskursen i Malå

OpenAIRE

Sjölander, Annika

2004-01-01

At the centre of this study lies one of the critical questions faced by (late-)modern society, namely that of taking care of the long-lived radioactive waste from nuclear power production. The problems of nuclear waste management are pictured as embracing a complex web of essential issues for society today, in terms of both its capacities and its shortcomings – so called core issues. The principal aim of the thesis is to examine the nuclear waste discourse in Malå, Västerbotten, from a critic...

Recombinant Mal d 1 facilitates sublingual challenge tests of birch pollen-allergic patients with apple allergy.

Science.gov (United States)

Kinaciyan, T; Nagl, B; Faustmann, S; Kopp, S; Wolkersdorfer, M; Bohle, B

2016-02-01

It is still unclear whether allergen-specific immunotherapy (AIT) with birch pollen improves birch pollen-related food allergy. One reason for this may be the lack of standardized tests to assess clinical reactions to birch pollen-related foods, for example apple. We tested the applicability of recombinant (r) Mal d 1, the Bet v 1-homolog in apple, for oral challenge tests. Increasing concentrations of rMal d 1 in 0.9% NaCl were sublingually administered to 72 birch pollen-allergic patients with apple allergy. The dose of 1.6 μg induced oral allergy syndromes in 26.4%, 3.2 μg in 15.3%, 6.3 μg in 27.8%, 12.5 μg in 8.3%, 25 μg in 11.1%, and 50 μg in 4.2% of the patients. No severe reactions occurred. None of the patients reacted to 0.9% NaCl alone. Sublingual administration of 50 μg of rMal d 1 induced no reactions in three nonallergic individuals. Our approach allows straight forward, dose-defined sublingual challenge tests in a high number of birch pollen-allergic patients that inter alia can be applied to evaluate the therapeutic efficacy of birch pollen AIT on birch pollen-related food allergy. © 2015 The Authors. Allergy Published by John Wiley & Sons Ltd.

Arte y Terapia. Historia, Interrelaciones, Praxis y Situación Actual

OpenAIRE

Tedejo Rodríguez, Estifen

2016-01-01

[ES] “Arte y terapia. Historia, Interrelaciones, praxis y situación actual” El Arteterapia parte de la idea motriz de que específicamente, las representaciones visuales objetivadas a través del material plástico contribuyen de manera sustancial a la construcción de significados en los conflictos psíquicos, favoreciendo su resolución. La representación plástica sería, desde esta óptica, un proceso fundamental como forma de interlocución para explorar y construir el pensamiento. Este p...

ANALISA PERBEDAAN MOTIVASI DAN PERSEPSI BERBELANJA DI MAL ANTARA ORANG TUA (IBU DAN PARA REMAJA PUTRINYA

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Sasung Luckytawati

2008-10-01

The conceptual framework consists of the following constructs: consumption motivation social and con umption motivation objective as independent variables, and Mall Perception that consist ambience, design, layout, variety, excitement, involvement, desire to stay and desire to return as dependent variable. Moreover, five hypotheses were developed and tested. instrument test of validity and reliability used to test the measures, while independent t-test and multiple regressions were used in hypotheses testing. Data were collected from 100 dyadic pairs of mothers and daughters who had recently visited Mal at Jakarta. The resuIts indicate that mothers and daughters are motivated to consume by different factors, and tha they differ significantly in terms of their perceptions of critical mal environmental variables. Keywords: Consumption motivation social, Consumer behaviour, Mall Perception, and Design factors.

Innovation management from the inside: An approach from attention and everyday praxis

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Fran Morente

2017-08-01

Originality/value: The originality of the present study is in two sense: the conceptual framework explores innovation management for the first time through attention; under the methodological framework, we leave aside the hegemonic quantitative-structural approach, to focus the study in the everyday life of Innovation Project Managers (the organizational agents, who actually go on to implement innovation management. Thus, we elude the discursive rhetoric of innovation to cling to the real praxis, that by which organizations will get results and survive.

Sobre a psicogênese do "mal de engasgo"

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Durval Marcondes

1947-06-01

Full Text Available O A. ressalta o aspecto psicológico da etiologia do cardiospasmo ou mal de engasgo, assunto até agora não abordado nos meios científicos brasileiros. Sem pretender afastar outros elementos causais que tenham sido, porventura, verificados e que poderão, talvez, agir concomitantemente, o A. é de opinião que o mal de engasgo é um disturbio funcional condicionado psìquicamente, cujas conseqüências se tornam irreversíveis depois de certo tempo. As conclusões apresentadas baseiam-se no material fornecido por pacientes em tratamento psicanalítico que apresentam fenômenos disfágicos, e por vários casos das clínicas de orientação infantil entre cujos problemas se incluem, além da dificuldade de engulir, a anorexia e a bulimia. Com respeito às atividades emocionais típicas que formam o substrato psicológico do mal de engasgo, o ponto fundamental está em que êste representa um compromisso, expresso ao nível oral, entre tendências passivo-receptivas e ativo-expulsivas. A essa situação psíquica correspondem condições de ambiente, atuais ou pretéritas, que, de modo contraditório, favorecem uma atitude de dependência infantil, ao mesmo tempo que acarretam repetidas frustrações. Trata-se, em geral, de mães dominadoras que, enquanto superprotegem a criança, agem para com ela com demasiado rigor. A superproteção centraliza-se sobretudo no que se refere aos alimentos, que se investem, assim, de grande significado emocional. O A. apresenta o resumo de uma observação clínica que apoia seu ponto de vista. Também a anorexia e a bulimia, em seu substrato psicodinâmico, estão relacionadas com o problema do apego e da emancipação e giram em torno da pessoa da mãe e da função alimentar. A solução do conflito faz-se, porém, num dos casos, pela rejeição do alimento e, noutro, pela avidez. O mal de engasgo constitui o meio têrmo entre os dois extremos. Existem, igualmente, nas neuroses gástricas e em sua conseq

Utilizing the Critical Inclusive Praxis: The Voyage of Five Selected School Principals in Building Inclusive School Cultures

Science.gov (United States)

Osiname, Ayodeji Tolulope

2018-01-01

This article integrates relevant literature with the lived experiences of five school principals regarding how they utilized different leadership styles to build an inclusive school culture. The conceptual framework--a Critical Inclusive Praxis, including culture, change, leadership, inclusion and challenge--provided a base for the literature and…

Crystallization, data collection and data processing of maltose-binding protein (MalE) from the phytopathogen Xanthomonas axonopodis pv. citri

International Nuclear Information System (INIS)

Souza, C. S.; Ferreira, L. C. S.; Thomas, L.; Barbosa, J. A. R. G.; Balan, A.

2009-01-01

The Xanthomonas axonopodis pv. citri maltose-binding protein MalE has been crystallized at 293 K using the hanging-drop vapour-diffusion method. Maltose-binding protein is the periplasmic component of the ABC transporter responsible for the uptake of maltose/maltodextrins. The Xanthomonas axonopodis pv. citri maltose-binding protein MalE has been crystallized at 293 K using the hanging-drop vapour-diffusion method. The crystal belonged to the primitive hexagonal space group P6 1 22, with unit-cell parameters a = 123.59, b = 123.59, c = 304.20 Å, and contained two molecules in the asymetric unit. It diffracted to 2.24 Å resolution

Caring as emancipatory nursing praxis: the theory of relational caring complexity.

Science.gov (United States)

Ray, Marilyn A; Turkel, Marian C

2014-01-01

In the culture of health care, nurses are challenged to understand their values and beliefs as humanistic within complex technical and economically driven bureaucratic systems. This article outlines the language of social justice and human rights and the advance of a Theory of Relational Caring Complexity, which offers insights into caring as emancipatory nursing praxis. Recommendations provide knowledge of the struggle to balance economics, technology, and caring. As nurses practice from a value-driven, philosophical, and ethical social justice framework, they will find "their voice" and realize the full potential that the power of caring has on patient and organizational outcomes.

Nursing praxis, compassionate caring and interpersonal relations: an observational study.

Science.gov (United States)

Fry, Margaret; MacGregor, Casimir; Ruperto, Kate; Jarrett, Kate; Wheeler, Janet; Fong, Jacqueline; Fetchet, Wendy

2013-05-01

The Clinical Initiative Nurse (CIN) is a role that requires experienced emergency nurses to assess, initiate diagnostic tests, treat and manage a range of patient conditions. The CIN role is focused on the waiting room and to 'communicate the wait', initiate diagnostics or treatment and follow-up for waiting room patients. We aim to explore what emergency nurses' do in their extended practice role in observable everyday life in the emergency department (ED). The paper argues that compassionate caring is a core nursing skill that supports CIN interpersonal relations, despite the role's highly clinical nature. Sixteen non-participant observations were undertaken in three EDs in New South Wales, Australia. Nurses were eligible for inclusion if they had two years of emergency experience and had worked in the CIN role for more than one year. All CIN's that were observed were highly experienced with a minimum three year ED experience. The CIN observations revealed how compassionate caring was utilised by CIN's to quickly build a therapeutic relationship with patients and colleagues, and helped to facilitate core communication and interpersonal skills. While the CIN role was viewed as extended practice, the role relied heavily on compassionate care to support interpersonal relationships and to actualise extended practice care. The study supports the contribution made by emergency nurses and demonstrates how compassionate caring is central to nursing praxis. This paper also demonstrates that the CIN role utilises a complex mix between advanced clinical skills and compassion that supports interpersonal and therapeutic relationships. Further research is needed to understand how compassionate care can be optimised within nursing praxis and the duty of care between nurses and patients, nurses and other health care professionals so that future healthcare goals can be realised. Copyright © 2013 College of Emergency Nursing Australasia Ltd. All rights reserved.

Towards radical praxis through a new formation in practice development

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Toni Wright

2017-11-01

Full Text Available Background: This article argues that achieving social and cultural transformation in healthcare, and beyond, needs to come from an orientation of explicit ethical stance around critical awareness and articulation of the affects of historical, political, social and cultural structures of oppression. There is discussion around how practice development language forms a discourse of harm, and how practice development environments reproduce and maintain structures of oppression. Aim: Drawing on the work of feminist critical social praxis concerned with corporeal experiences and the affects emanating from embodied practices, this article will bring to the fore marginalisations and oppressions experienced by particular bodies, and ask what do practice developers need to consider and act on to make practice development more socially just? Method: Application of feminist critical social praxis, a theoretical dimension thus far unexplored in the practice development field, as a framework for asking what practice development can learn. Particular attention is drawn to the benefits of orientating a new formation in practice development around the work of Black feminists and feminists of colour – of looking to the margins and bringing those centre. Findings: Illumination of new insights into how to build a feminist critical social justice oriented practice development through the explicit practice of naming and raising consciousness around the lived experiences and materiality of oppressed and marginalised peoples. Conclusion: Achieving radical cultural, social, political and economic transformation needs to come from an orientation of explicit critical awareness and recognition of the politics of affects of neoliberal, neo-colonial capitalist systems. Implications for practice: A feminist critical social justice ethical stance can enable practice development, as a methodology, and practice developers as implementers of that methodology, to respond to this

Praxis and reflexivity for interprofessional education: towards an inclusive theoretical framework for learning.

Science.gov (United States)

Hutchings, Maggie; Scammell, Janet; Quinney, Anne

2013-09-01

While there is growing evidence of theoretical perspectives adopted in interprofessional education, learning theories tend to foreground the individual, focusing on psycho-social aspects of individual differences and professional identity to the detriment of considering social-structural factors at work in social practices. Conversely socially situated practice is criticised for being context-specific, making it difficult to draw generalisable conclusions for improving interprofessional education. This article builds on a theoretical framework derived from earlier research, drawing on the dynamics of Dewey's experiential learning theory and Archer's critical realist social theory, to make a case for a meta-theoretical framework enabling social-constructivist and situated learning theories to be interlinked and integrated through praxis and reflexivity. Our current analysis is grounded in an interprofessional curriculum initiative mediated by a virtual community peopled by health and social care users. Student perceptions, captured through quantitative and qualitative data, suggest three major disruptive themes, creating opportunities for congruence and disjuncture and generating a model of zones of interlinked praxis associated with professional differences and identity, pedagogic strategies and technology-mediated approaches. This model contributes to a framework for understanding the complexity of interprofessional learning and offers bridges between individual and structural factors for engaging with the enablements and constraints at work in communities of practice and networks for interprofessional education.

Pragmatism, Praxis, and Naturalism: The Importance for Music Education of Intentionality and Consummatory Experience in Musical Praxes

Science.gov (United States)

Regelski, Thomas A.

2017-01-01

The overlapping of pragmatic philosophy and the Aristotelian concept of praxis is explored with application to music and music education. John Dewey's philosophy of "Art as Experience" is contrasted with tacit aesthetic assumptions about music that music teachers often hold as a result of the aesthetic meme inherited from their…

Isolation of Mal d 1 and Api g 1 - specific recombinant antibodies from mouse IgG Fab fragment libraries - Mal d 1-specific antibody exhibits cross-reactivity against Bet v 1.

Science.gov (United States)

Haka, Jaana; Niemi, Merja H; Iljin, Kristiina; Reddy, Vanga Siva; Takkinen, Kristiina; Laukkanen, Marja-Leena

2015-05-27

Around 3-5% of the population suffer from IgE-mediated food allergies in Western countries and the number of food-allergenic people is increasing. Individuals with certain pollen allergies may also suffer from a sensitisation to proteins in the food products. As an example a person sensitised to the major birch pollen allergen, Bet v 1, is often sensitised to its homologues, such as the major allergens of apple, Mal d 1, and celery, Api g 1, as well. Development of tools for the reliable, sensitive and quick detection of allergens present in various food products is essential for allergic persons to prevent the consumption of substances causing mild and even life-threatening immune responses. The use of monoclonal antibodies would ensure the specific detection of the harmful food content for a sensitised person. Mouse IgG antibody libraries were constructed from immunised mice and specific recombinant antibodies for Mal d 1 and Api g 1 were isolated from the libraries by phage display. More detailed characterisation of the resulting antibodies was carried out using ELISA, SPR experiments and immunoprecipitation assays. The allergen-specific Fab fragments exhibited high affinity towards the target recombinant allergens. Furthermore, the Fab fragments also recognised native allergens from natural sources. Interestingly, isolated Mal d 1-specific antibody bound also to Bet v 1, the main allergen eliciting the cross-reactivity syndrome between the birch pollen and apple. Despite the similarities in Api g 1 and Bet v 1 tertiary structures, the isolated Api g 1-specific antibodies showed no cross-reactivity to Bet v 1. Here, high-affinity allergen-specific recombinant antibodies were isolated with interesting binding properties. With further development, these antibodies can be utilised as tools for the specific and reliable detection of allergens from different consumable products. This study gives new preliminary insights to elucidate the mechanism behind the pollen

Competence and Praxis: Sequential Analysis in German Sociology

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Kai-Olaf Maiwald

2005-09-01

Full Text Available In German social research nowadays most qualitative methodologies employ sequential analysis. This article explores the similarities and differences in conceptualising and practising this method. First, the working consensus, conceived as a shared set of methodological assumptions, is explicated. Second, with regard to three major paradigms of qualitative research in Germany—conversation analysis, objective hermeneutics, and hermeneutic sociology of knowledge—the dif­ferent ways of doing sequential analysis are investigated to locate the points of departure from a working consensus. It is argued that differences arise from different case-perspectives and, relative to that, from different modes of introducing general knowl­edge, i.e. knowledge that is not specific for the analysed case, into the interpretation. An import­ant notion to emerge from the comparison is the distinction between competence and praxis. URN: urn:nbn:de:0114-fqs0503310

Hybrid (laparoscopy + stent treatment of celiac trunk compression syndrome (Dunbar syndrome, median arcuate ligament syndrome (MALS

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Maciej Michalik

2016-12-01

Full Text Available Introduction : Celiac trunk (CT compression syndrome caused by the median arcuate ligament (MAL is a rarely diagnosed disease because of its nonspecific symptoms, which cause a delay in the correct diagnosis. Intestinal ischemia occurs, which causes symptoms of abdominal angina. One method of treatment for this disease is surgical release of the CT – the intersection of the MAL. Laparoscopy is the first step of the hybrid technique combined with percutaneous angioplasty and stenting of the CT. Aim: To demonstrate the usefulness and advantages of the laparoscopic approach in the treatment of Dunbar syndrome. Material and methods : Between 2013 and 2016 in the General and Minimally Invasive Surgery Department of the Medical Sciences Faculty of the University of Warmia and Mazury in Olsztyn, 6 laparoscopic procedures were performed because of median arcuate ligament syndrome. During the laparoscopy the MAL was cut with a harmonic scalpel. One month after laparoscopy 5 patients had Doppler percutaneous angioplasty of the CT with stent implantation in the Vascular Surgery Department in Pomeranian Medical University in Szczecin. Results : In one case, there was a conversion of laparoscopic surgery to open due to unmanageable intraoperative bleeding. In one case, postoperative ultrasound examination of the abdominal cavity demonstrated the presence of a large hematoma in the retroperitoneal space. All patients reported relief of symptoms in the first days after the operation. Conclusions : The hybrid method, combining laparoscopy and angioplasty, seems to be a long-term solution, which increases the comfort of the patient, brings the opportunity for normal functioning and minimizes the risk of restenosis.

Hybrid (laparoscopy + stent) treatment of celiac trunk compression syndrome (Dunbar syndrome, median arcuate ligament syndrome (MALS)).

Science.gov (United States)

Michalik, Maciej; Dowgiałło-Wnukiewicz, Natalia; Lech, Paweł; Majda, Kaja; Gutowski, Piotr

2016-01-01

Celiac trunk (CT) compression syndrome caused by the median arcuate ligament (MAL) is a rarely diagnosed disease because of its nonspecific symptoms, which cause a delay in the correct diagnosis. Intestinal ischemia occurs, which causes symptoms of abdominal angina. One method of treatment for this disease is surgical release of the CT - the intersection of the MAL. Laparoscopy is the first step of the hybrid technique combined with percutaneous angioplasty and stenting of the CT. To demonstrate the usefulness and advantages of the laparoscopic approach in the treatment of Dunbar syndrome. Between 2013 and 2016 in the General and Minimally Invasive Surgery Department of the Medical Sciences Faculty of the University of Warmia and Mazury in Olsztyn, 6 laparoscopic procedures were performed because of median arcuate ligament syndrome. During the laparoscopy the MAL was cut with a harmonic scalpel. One month after laparoscopy 5 patients had Doppler percutaneous angioplasty of the CT with stent implantation in the Vascular Surgery Department in Pomeranian Medical University in Szczecin. In one case, there was a conversion of laparoscopic surgery to open due to unmanageable intraoperative bleeding. In one case, postoperative ultrasound examination of the abdominal cavity demonstrated the presence of a large hematoma in the retroperitoneal space. All patients reported relief of symptoms in the first days after the operation. The hybrid method, combining laparoscopy and angioplasty, seems to be a long-term solution, which increases the comfort of the patient, brings the opportunity for normal functioning and minimizes the risk of restenosis.

Escaping History: Benjamin Fondane's 'Mal des fantômes' and Interiority

OpenAIRE

Dickow, A

2017-01-01

AbstractThis article undertakes a detailed comparison of the work of Emmanuel Levinas and the poet-philosopher Benjamin Fondane. Fondane’s most iconic poem, quoted at the entrance to the Hall of Names in Jerusalem’s Holocaust museum, resembles a poetic illustration of Levinas’s key themes, such as the ‘face’ and the concept of ‘ethical speech.’ Likewise, Fondane’s long poem ‘Le Mal des fantômes’ illustrates Levinas and Fondane’s shared conception of the subject’s interiority and day-to-day ex...

Telos versus Praxis in Bioethics.

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Chambers, Tod S

2016-09-01

The authors of "A Conceptual Model for the Translation of Bioethics Research and Scholarship" argue that bioethics must respond to institutional pressures by demonstrating that it is having an impact in the world. Any impact, the authors observe, must be "informed" by the goals of the discipline of bioethics. The concept of bioethics as a discipline is central to their argument. They begin by citing an essay that Daniel Callahan wrote in the first issue of Hastings Center Studies. Callahan argued in this 1973 piece that bioethics had yet to attain the status of a discipline, and he lauded the freedom of being able to define a new discipline. Callahan's essay shares with Mathews and colleague's a peculiarity: neither ever defines what it means to refer to something as a "discipline." To define a discipline does mean attending to the intended end product of scholarly activity, so I concur with Mathews et al.'s focus on outcomes. But I am concerned that in their argument they confusingly entangle their understanding of an academic discipline's internal goals, its telos, with its potential to have an impact on the external world, its praxis. The confusion that this can bring exposes what I believe is a profound problem within bioethics, the discipline's peculiar and at times intellectually hazardous relationship with its institutional hosts. © 2016 The Hastings Center.

Characterization of recombinant Mal d 4 and its application for component-resolved diagnosis of apple allergy

NARCIS (Netherlands)

Ma, Y.; Zuidmeer, L.; Bohle, B.; Bolhaar, S. T. H.; Gadermaier, G.; Gonzalez-Mancebo, E.; Fernandez-Rivas, M.; Knulst, A. C.; Himly, M.; Asero, R.; Ebner, C.; van Ree, R.; Ferreira, F.; Breiteneder, H.; Hoffmann-Sommergruber, K.

2006-01-01

BACKGROUND: Profilins are ubiquitous panallergens that have been extensively characterized; yet, their clinical relevance is still unclear. OBJECTIVE: The aim of the present study was to produce recombinant apple profilin (rMal d 4) and to evaluate its allergenic activity and its potency for

First successful reduction of clinical allergenicity of food by genetic modification: Mal d 1-silenced apples cause fewer allergy symptoms than the wild-type cultivar.

Science.gov (United States)

Dubois, A E J; Pagliarani, G; Brouwer, R M; Kollen, B J; Dragsted, L O; Eriksen, F D; Callesen, O; Gilissen, L J W J; Krens, F A; Visser, R G F; Smulders, M J M; Vlieg-Boerstra, B J; Flokstra-de Blok, B J; van de Weg, W E

2015-11-01

Genetic modification of allergenic foods such as apple has the potential to reduce their clinical allergenicity, but this has never been studied by oral challenges in allergic individuals. We performed oral food challenges in 21 apple-allergic individuals with Elstar apples which had undergone gene silencing of the major allergen of apple, Mal d 1, by RNA interference. Downregulation of Mal d 1 gene expression in the apples was verified by qRT-PCR. Clinical responses to the genetically modified apples were compared to those seen with the wild-type Elstar using a visual analogue scale (VAS). Gene silencing produced two genetically modified apple lines expressing Mal d 1.02 and other Mal d 1 gene mRNA levels which were extensively downregulated, that is only 0.1-16.4% (e-DR1) and 0.2-9.9% (e-DR2) of those of the wild-type Elstar, respectively. Challenges with these downregulated apple lines produced significantly less intense maximal symptoms to the first dose (Vmax1) than with Elstar (Vmax1 Elstar 3.0 mm vs 0.0 mm for e-DR1, P = 0.017 and 0.0 mm for e-DR2, P = 0.043), as well as significantly less intense mean symptoms per dose (meanV/d) than with Elstar (meanV/d Elstar 2.2 mm vs 0.2 mm for e-DR1, P = 0.017 and 0.0 mm for e-DR2, P = 0.043). Only one subject (5%) remained symptom-free when challenged with the Elstar apple, whereas 43% did so with e-DR1 and 63% with e-DR2. These data show that mRNA silencing of Mal d 1 results in a marked reduction of Mal d 1 gene expression in the fruit and reduction of symptoms when these apples are ingested by allergic subjects. Approximately half of the subjects developed no symptoms whatsoever, and virtually all subjects wished to consume the apple again in the future. © 2015 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

The Paradox and Fog of Supervision: Site for the Encounters and Growth of Praxis, Persons and Voices

Science.gov (United States)

Cherry, Nita

2012-01-01

Purpose: Several paradoxes have been presented in the literature as inherent in supervision of doctoral students. The purpose of this paper is to explore these paradoxes and offer the concept of praxis as a way of effectively engaging with complex and paradoxical dimensions of supervision, rather than denying or avoiding them.…

Efeito de ação educativa participativa no conhecimento de professores do ensino básico sobre malária

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Martha Cecilia Suárez-Mutis

2011-10-01

Full Text Available OBJETIVO: Descrever uma estratégia educativa participativa de construção de conhecimentos relacionados à malária entre professores em um município altamente endêmico. MÉTODOS: Foi feito um estudo observacional. Um curso de 40 horas foi realizado sob enfoque multidisciplinar e problematizador para 46 professores, prioritariamente da área rural, no município de Barcelos, AM, em 2008. O processo educativo participativo incluiu oficinas e aulas práticas. Para investigar os conhecimentos, aplicou-se um questionário previamente validado, antes e após o curso, avaliado por abordagens quantitativa e qualitativa usando a análise temática para respostas abertas. RESULTADOS: Previamente ao curso, os professores tinham pouca informação sobre os mecanismos de transmissão, meios de prevenção e a associação da malária aos seus vetores, bem como conceitos restritos sobre saúde. Após o curso, não somente aumentou o conhecimento dos professores sobre a malária como também emergiram reflexões sobre o papel do professor na sociedade. CONCLUSÕES: O efeito da ação educativa na construção de um saber contextualizado sobre malária e saúde indica o potencial da estratégia desenvolvida. Processos de educação permanente são necessários à sustentabilidade dos novos saberes e práticas, orientados pela promoção da saúde.

Preparation of MAl 2 O 4 : Eu 2+ , Sm 3+ (M = Ca, Sr, Ba) Phosphors ...

African Journals Online (AJOL)

A series of MAl2O4: Eu2+, Sm3+ (M = Ca, Sr, Ba) phosphors was prepared by the combustion method, and the influence of these alkaline earth metals on the structure and luminescent performances for these phosphors was investigated. A relationship was established between their composition, crystallization capacity and ...

Preparation of MAl O : Eu2+, Sm3+ (M = Ca, Sr, Ba) Phosphors by ...

African Journals Online (AJOL)

NJD

2007-10-15

Oct 15, 2007 ... clearly show that most peaks are assigned to those of the MAl2O4 structure. Moreover, their structures change with change of M. Samples A and B exhibit monoclinic crystal systems and sample. C a hexagonal structure. The doping Eu2+ and co-doping Sm3+ have very little influence on the structure of the ...

The use of plasma rich in growth factors (PRGF-Endoret) in the treatment of a severe mal perforant ulcer in the foot of a person with diabetes.

Science.gov (United States)

Orcajo, Beatriz; Muruzabal, Francisco; Isasmendi, María Concepción; Gutierrez, Nerea; Sánchez, Mikel; Orive, Gorka; Anitua, Eduardo

2011-08-01

A 71 year old person with diabetes with a severe mal perforant ulcer in the right foot was treated twice with autologous plasma-rich in growth factors (PRGF) obtained from her own blood. After PRGF treatment the severe mal perforant ulcer completely healed in 10 weeks. Copyright © 2011 Elsevier Ireland Ltd. All rights reserved.

COMPREENDER OS DIREITOS HUMANOS EM CABO VERDE: da retórica político-filosófica à praxis jurídica

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Nataniel Andrade Monteiro

2016-07-01

Full Text Available O artigo procura analisar a coerência entre a retórica político-filosófica e a praxis jurídica, tendo como locus de análise os direitos humanos em Cabo Verde. Numa perspectiva histórica, a afirmação dos direitos humanos aconteceu de forma paulatina num processo de sucessivas lutas e revindicações que culminaram em 1948 com a Declaração Universal dos Direitos Humanos. A Declaração é protegida pelo ordenamento jurídico de diferentes Estados e é um dos temas mais debatidos a nível mundial. O caso de Cabo Verde não constitui excepção a este fenómeno, apesar de ser um Estado modelo em África em matéria de direitos humanos. Porém, existem preocupações no que se refere às denúncias de violações constantes como sejam: a morosidade da justiça, as condições precárias das instalações prisionais, os abusos por parte de agentes policiais, a hostilidade contras as mulheres e os abusos contra as crianças. Deste modo, procuramos compreender esta problemática à luz da filosofia política contemporânea, analisando para o efeito um conjunto de perspectivas que configuram a retórica político-filosófica e a práxis jurídica. Palavras-chave: Democracia; Direitos Humanos; Retórica Político-filosófica; Praxis Jurídica. UNDERSTANDING HUMAN RIGHTS IN CAPE VERDE: Political-philosophical rhetoric to legal praxis ABSTRACT The article seeks to analyses the coherence between the political-philosophical rhetoric and legal praxis, with the locus of human rights analysis in Cape Verde. In a historical perspective, the affirmation of human rights happened so gradual a process of successive fights and claims that culminated in 1948 with the Universal Declaration of Human Rights. The statement is protected by the legislation of different States and is one of the most discussed themes worldwide. The case of Cape Verde is no exception to this phenomenon, despite being a model State in Africa in the field of human rights. However

Ankündigung und Projektbeschreibung: Ich zeig es Dir - HOCH 2

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Sandra Schön

2012-12-01

Full Text Available Haben Sie schon mal mit einem Kurzvideo gelernt? Die Praxis zeigt, dass sich kurze Videos ideal für das Lehren und Lernen in Peer-to-Peer-Kontexten eignen. Seit Mitte Oktober 2012 produzieren Jugendliche zwischen 9 und 13 Jahren Unterrichtsvideos. Dieser Beitrag gibt einen kurzen Einblick in das laufende Projekt.Did you ever use short videos for teaching and learning? The project that is presented in this paper shows how young people from 9 to 13 years are producing short videos for teaching and learning in peer-to-peer contexts.

A review of the prevalence and factors responsible for mal-nutrition in Pakistan

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Hafsa Hina

2015-01-01

Full Text Available Problems occupying special attention identified by the World Health Organization also include Childhood malnutrition (Beagle hole et al., 1993. Development goals are also program by the United Nations to halve the problem of under nutrition (Alderman et al., 2005. Despite of the involvement of international organizations still under nutrition has a main contribution to the high mortality rate of the children in the most part of the world (Caulfield et al., 2004. Poverty plays a main part in the high prevalence of childhood under nutrition. The child is said to be under-weight when its weight is lower than the weight of the reference rage for that age. The weight for height deficiency is known as wasting, while height for age deficiency as stunting. Wasting may be due to acute food shortage while prolonged food deprivation can cause stunting (Cosminsky et al., 1993; de Onis et al., 2000; Fernandez et al., 2002; and Zere & McIntyre, 2003. The factors responsible for the predisposition of children to mal nutrition vary and ranges from political instability to the economical status of the area (de Onis et al., 2000. Therefore protocols developed for the preventive measures of mal-nutrition should be multifaceted. 

Migrações internas e malária urbana - Bahia, Brasil Internal migration and urban malaria - Bahia, Brazil

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Sebastião Loureiro de Souza

1986-10-01

Full Text Available Estuda-se as características sócio-econômicas dos indivíduos acometidos pela malária, em 1983, na área urbana de Camaçari - Bahia, Brasil, com destaque para os subgrupos migrantes e não migrantes. As condições de vida precárias de ambos os subgrupos são apontadas como os determinantes do surto de malária desencadeado no local.It is proposed to study the socio-economic characteristics of individuals who were infected with malaria in the urban area of Camaçari, Bahia, Brazil, in 1983. Special emphasis being given to the subgroups of migrants and nonmigrants. The precarious living conditions of both subgroups are identified as determinative of the malaria outbreak which occurred there.

Ta splanchna: A theopaschitic approach to a hermeneutics of God’s praxis. From zombie categories to passion categories in theory formation for a practical theology of the intestines

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Daniel J. Louw

2011-11-01

Full Text Available It is argued that both the traditional clerical paradigm of an ecclesial approach and the phenomenological paradigm of an empirical approach are not sufficient enough to describe and maintain a theological methodology in practical theology. This has led to the introduction of a theopaschitic paradigm in theory formation. It is argued that the normative task of practical theology implies a philosophical-hermeneutical dimension, that is, to interpret under girding paradigms as related to meaning and being. It also implies a theological dimension; to reflect theologically on the praxis of God as an influential factor within human actions (inhabitational theology. With reference to ‘the pneumatological praxis of God’, a practical theology of the intestines is proposed. Bowel categories reveal a divine intentionality (teleology and describe a modus of God’s praxis, the how of God within the vulnerability and suffering of human beings. This divine ontological mode should operate as a practical theological paradigm determining being qualities (ontic status within human actions and processes of communication. The under girding theological presupposition is that ta splanchna [strong feeling of mercy and compassion expressed by the intestines] denotes a compassionate praxis of co-suffering (the passio Dei. Passion in practical theology emanates in parrhesia and instills a vivid hope: fides quaerens spem [faith in search of hope].

The Effects of Rhythm and Robotic Interventions on the Imitation/Praxis, Interpersonal Synchrony, and Motor Performance of Children with Autism Spectrum Disorder (ASD): A Pilot Randomized Controlled Trial

Science.gov (United States)

Srinivasan, Sudha M.; Kaur, Maninderjit; Park, Isabel K.; Gifford, Timothy D.; Marsh, Kerry L.; Bhat, Anjana N.

2015-01-01

We assessed the effects of three interventions, rhythm, robotic, and standard-of-care, on the imitation/praxis, interpersonal synchrony, and overall motor performance of 36 children with Autism Spectrum Disorder (ASD) between 5 and 12 years of age. Children were matched on age, level of functioning, and services received, prior to random assignment to one of the three groups. Training was provided for 8 weeks with 4 sessions provided each week. We assessed generalized changes in motor skills from the pretest to the posttest using a standardized test of motor performance, the Bruininks-Oseretsky Test of Motor Proficiency, 2nd edition (BOT-2). We also assessed training-specific changes in imitation/praxis and interpersonal synchrony during an early and a late session. Consistent with the training activities practiced, the rhythm and robot groups improved on the body coordination composite of the BOT-2, whereas the comparison group improved on the fine manual control composite of the BOT-2. All three groups demonstrated improvements in imitation/praxis. The rhythm and robot groups also showed improved interpersonal synchrony performance from the early to the late session. Overall, socially embedded movement-based contexts are valuable in promoting imitation/praxis, interpersonal synchrony, and motor performance and should be included within the standard-of-care treatment for children with ASD. PMID:26793394

The Effects of Rhythm and Robotic Interventions on the Imitation/Praxis, Interpersonal Synchrony, and Motor Performance of Children with Autism Spectrum Disorder (ASD: A Pilot Randomized Controlled Trial

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Sudha M. Srinivasan

2015-01-01

Full Text Available We assessed the effects of three interventions, rhythm, robotic, and standard-of-care, on the imitation/praxis, interpersonal synchrony, and overall motor performance of 36 children with Autism Spectrum Disorder (ASD between 5 and 12 years of age. Children were matched on age, level of functioning, and services received, prior to random assignment to one of the three groups. Training was provided for 8 weeks with 4 sessions provided each week. We assessed generalized changes in motor skills from the pretest to the posttest using a standardized test of motor performance, the Bruininks-Oseretsky Test of Motor Proficiency, 2nd edition (BOT-2. We also assessed training-specific changes in imitation/praxis and interpersonal synchrony during an early and a late session. Consistent with the training activities practiced, the rhythm and robot groups improved on the body coordination composite of the BOT-2, whereas the comparison group improved on the fine manual control composite of the BOT-2. All three groups demonstrated improvements in imitation/praxis. The rhythm and robot groups also showed improved interpersonal synchrony performance from the early to the late session. Overall, socially embedded movement-based contexts are valuable in promoting imitation/praxis, interpersonal synchrony, and motor performance and should be included within the standard-of-care treatment for children with ASD.

Malé osobnosti veľkých dejín – veľké osobnosti malých dejín IV. Príspevky k hudobnej regionalistike, Slovenské národné múzeum – Hudobné múzeum, Brämerova kúria, Bratislava 30. listopadu – 1. prosince 2017

Czech Academy of Sciences Publication Activity Database

Kachlík, Jan

2018-01-01

Roč. 55, č. 1 (2018), s. 102-104 ISSN 0018-7003. [Malé osobnosti veľkých dejín – veľké osobnosti malých dejín IV. Príspevky k hudobnej regionalistike. Bratislava, 30.11.2017-01.12.2017] Institutional support: RVO:68378076 Keywords : music ology * conference Subject RIV: AL - Art, Architecture, Cultural Heritage OBOR OECD: Performing arts studies ( Music ology, Theater science, Dramaturgy)

A critique of Bernstein's beyond objectivism and relativism: science, hermeneutics, and praxis.

Science.gov (United States)

Matusitz, Jonathan; Kramer, Eric

2011-06-01

This analysis comments on Bernstein's lack of clear understanding of subjectivity, based on his book, Beyond Objectivism and Relativism: Science, Hermeneutics, and Praxis. Bernstein limits his interpretation of subjectivity to thinkers such as Gadamer and Habermas. The authors analyze the ideas of classic scholars such as Edmund Husserl and Friedrich Nietzsche. Husserl put forward his notion of transcendental subjectivity and phenomenological ramifications of the relationship between subjectivity and objectivity. Nietzsche referred to subjectivity as "perspectivism," the inescapable fact that any and all consciousnesses exist in space and time. Consciousness is fundamentally constituted of cultural, linguistic, and historical dimensions.

Malária grave importada: relato de caso Severe imported malaria: case report

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Alessandra Alves

2007-06-01

Full Text Available JUSTIFICATIVA E OBJETIVOS: A malária ainda representa um problema de saúde global. A forma grave da doença é causada principalmente por P. falciparum e pode cursar com complicações cerebrais, renais, pulmonares, hematológicas, circulatórias e hepáticas. O objetivo deste estudo foi relatar um caso de paciente portador de malária grave importada. RELATO DO CASO: Paciente do sexo masculino, 30 anos, pardo, filipino, marinheiro, proveniente de embarcação vinda da Nigéria, com história de dor abdominal no hipocôndrio direito, icterícia, febre e rebaixamento do nível de consciência. Os exames laboratoriais de admissão mostraram hiperbilirrubinemia de 50 mg/dL, acidose metabólica grave, trombocitopenia, creatinina de 5,6 mg/dL, leucocitose com desvio até metamielócitos. O escore APACHE II foi de 37, com risco de óbito de 88%. Durante a internação foi diagnosticada malária por P. falciparum pelo teste de gota espessa. Mesmo com tratamento antimalárico adequado, o paciente evoluiu com insuficiência renal aguda necessitando de hemodiálise e síndrome de angústia respiratória aguda (SARA, necessitando de ventilação mecânica (VM, choque refratário tratado com aminas vasoativas, além de quadro hematológico, configurando um caso grave de disfunção de múltiplos de órgãos. Ainda apresentou pneumonia associada à VM e sepse relacionada ao uso de cateteres. Após a alta hospitalar, o paciente não apresentou seqüelas cerebral, pulmonar ou renal. CONCLUSÕES: Dos critérios definidores de malária grave descritos na literatura, o paciente preenchia: insuficiência renal aguda, síndrome da angústia respiratória aguda (SARA, acidose metabólica, alteração do nível de consciência, hemoglobinúria macroscópica, hiperparasitemia e hiperbilirrubinemia, que se relaciona a uma mortalidade maior que 10%, na dependência do tratamento precoce e dos recursos disponíveis. A malária grave exige diagnóstico e tratamento

Transglycosylation properties of maltodextrin glucosidase (MalZ) from Escherichia coli and its application for synthesis of a nigerose-containing oligosaccharide

Energy Technology Data Exchange (ETDEWEB)

Song, Kyung-Mo [Center for Agricultural Biomaterials and Department of Food Science and Biotechnology, Seoul National University, Seoul 151-921 (Korea, Republic of); Shim, Jae-Hoon [Department of Biology, University of Incheon, Incheon 406-772 (Korea, Republic of); Park, Jong-Tae; Kim, Sung-Hee [Center for Agricultural Biomaterials and Department of Food Science and Biotechnology, Seoul National University, Seoul 151-921 (Korea, Republic of); Kim, Young-Wan [Department of Food and Biotechnology, Korea University, Jochiwon 339-700 (Korea, Republic of); Boos, Winfried [Department of Biology, University of Konstanz, Konstanz 78457 (Germany); Park, Kwan-Hwa, E-mail: parkkh@incheon.ac.kr [Department of Biology, University of Incheon, Incheon 406-772 (Korea, Republic of)

2010-06-18

The transglycosylation reaction of maltodextrin glucosidase (MalZ) cloned and purified from Escherichia coli K12 was characterized and applied to the synthesis of branched oligosaccharides. Purified MalZ preferentially catalyzed the hydrolysis of maltodextrin, {gamma}-cyclodextrin (CD), and cycloamylose (CA). In addition, when the enzyme was incubated with 5% maltotriose (G3), a series of transfer products were produced. The resulting major transfer products, annotated as T1, T2, and T3, were purified and their structures were determined by TLC, MALDI-TOF/MS, {sup 13}C NMR, and enzymatic analysis. T1 was identified as a novel compound, maltosyl {alpha}-1,3-maltose, whereas T2 and T3 were determined to be isopanose and maltosyl-{alpha}-1,6-maltose, respectively. These results indicated that MalZ transferred sugar moiety mainly to C-3 or C-6-OH of glucose of the acceptor molecule. To obtain highly concentrated transfer products, the enzyme was reacted with 10% liquefied cornstarch, and then glucose and maltose were removed by immobilized yeast. The T1 content of the resulting reaction mixture reached 9.0%. The mixture of T1 containing a nigerose moiety can have an immunopotentiating effect on the human body and may be a potential functional sugar stuff.

Alterações do desenvolvimento de crianças prematuras nascidas de mães com malária no periodo gestacional

OpenAIRE

Simões, Maria da Conceição Ribeiro

2012-01-01

Objetivo : O estudo buscou avaliar as alterações no desenvolvimento de crianças prematuras nascidas de mães com malária no periodo gestacional, em Porto Velho, Rondônia. O objetivo principal é descrever as alterações encontradas nessas crianças aplicando um teste preditivo para alterações no desenvolvimento e compará-las à um grupo controle de crianças prematuras nascidas de mães que não apresentaram malária no periodo gestacional. Métodos : Por ser um estudo do tipo transvers...

Differences in Praxis Performance and Receptive Language during Fingerspelling between Deaf Children with and without Autism Spectrum Disorder

Science.gov (United States)

Bhat, Anjana N.; Srinivasan, Sudha M.; Woxholdt, Colleen; Shield, Aaron

2018-01-01

Children with autism spectrum disorder present with a variety of social communication deficits such as atypicalities in social gaze and verbal and non-verbal communication delays as well as perceptuo-motor deficits like motor incoordination and dyspraxia. In this study, we had the unique opportunity to study praxis performance in deaf children…

La naturaleza del mal en el pensamiento de Hannah Arendt | The nature of evil in Hannah Arendt’s thinking

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María Cristina Hermida del Llano

2016-12-01

Full Text Available RESUMEN. La cuestión del mal ocupa un lugar central en el pensamiento de Hannah Arendt al constituir un concepto transversal que recorre todos sus trenes de pensamiento. Se somete a análisis la “naturaleza del mal” a través del estudio de su obra y de su propia experiencia vital, especialmente al cubrir el juicio de Eichmann en Jerusalén, donde ella afirmaría que éste representaba “la banalidad del mal”. Se trata de averiguar si en su particular concepción del mal influyó Voltaire, por qué surge el mal, por qué se manifiesta de forma permanente en la historia y si puede ser destruido   ABSTRACT. The topic of evil has a central place in Hannah Arendt’s thinking as it lies at the core of all her trains of thought. We analyze the “nature of evil” in Hannah Arendt’s philosophy through the study of her work and of her life experience, especially when she covered the trial of Eichmann in Jerusalem where she pointed out that Eichmann represented “the banality of evil”. Our goal in this contribution is to understand whether the philosophy of Voltaire could have influenced Arendt’s conception of evil, why it arises, why it persists throughout history, and whether it can be destroyed

No Time for Nostalgia!: Asylum-Making, Medicalized Colonialism in British Columbia (1859-97) and Artistic Praxis for Social Transformation

Science.gov (United States)

Roman, Leslie G.; Brown, Sheena; Noble, Steven; Wainer, Rafael; Young, Alannah Earl

2009-01-01

This article asks: How have disability, indigenous arts and cultural praxis transformed and challenged the historical sociological archival research into relationships among asylum-making, medicalized colonialism and eugenics in the Woodlands School, formerly the Victoria Lunatic Asylum, the Provincial Asylum for the Insane in Victoria, BC 1859-72…

A banalidade do mal e as possibilidades da educação moral: contribuições arendtianas

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Marcelo Andrade

2010-01-01

Full Text Available Más que una época de crisis, enfrentamos hoy una crisis de época en la cual la educación desempeña un papel fundamental. En este sentido, el presente trabajo es una relectura de la obra de Hannah Arendt, filósofa que pensó y vivió en tiempos sombríos, con el fin de aclarar algunos conceptos que son fundamentales para que hoy pueda repensarse la educación moral o la educación en valores. A través de un estudio centrado en las obras Eichmann en Jerusalén: un estudio sobre la banalidad del mal y La vida del espíritu, este trabajo busca comprender cómo y por qué Hannah Arendt acuñó el concepto banalidad del mal y en qué sentido este se relaciona con el vacío del pensamiento y con una propuesta de educación en valores.

On the societal nature of praxis and organic research

Science.gov (United States)

Roth, Wolff-Michael

2016-03-01

In its focus on social practices, the feature article presents an interesting theoretical framework for rethinking not only where and how knowing and learning in science education exhibit themselves but also we might change our own research practice. The framework is not new to me, as I have advocated it explicitly for more than 15 years. But over time it became apparent to me that some particularities of participation in practice may be grounded more strongly in an orientation towards the societal nature of any human praxis. In this forum contribution, I present a theoretical approach built on societal-historical activity theory that also takes activism as a major category for theorizing participation. This approach not only covers the extent of the social practice framework but also allows us to make thematic the production of inequity and restrictions to access science and engineering that are characteristic of many societies.

Teaching Resistance to Narrative: Brecht's Theater Praxis as a Response to Florian Henckel Von Donnersmarck's "Das Leben der Anderen"

Science.gov (United States)

Koerner, Morgan

2016-01-01

This article explores the potential of Brecht's theater praxis for teaching millennial students to question dramatic narratives and rethink their own spectatorial positions, especially in regards to mainstream cinema that emphasizes character identification and plot. The article reflects on a five-day teaching unit on Brecht's theater in a senior…

Fingerpainting am Touchscreen. Fünf Mal- und Zeichen-Apps für Android-Tablets

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Christoph Kaindel

2015-06-01

Full Text Available Malen auf dem Touchscreen eines Smartphones oder Tablets ist eine natürliche und intuitive Tätigkeit; anders als bei der Nutzung eines Grafiktabletts am PC gibt es so gut wie keine Umstellungsphase. Christoph Kaindel hat für uns fünf Mal- und Zeichen-Apps unter die Lupe genommen. Bereits für Kinder ist in den diversen Appstores eine große Zahl an einfachen Mal-Apps zu finden, mit meist nur wenigen Einstellungsmöglichkeiten und oft fragwürdiger Qualität. Am anderen Ende des Spektrums liegt der professionelle Einsatz von Tablets im Grafikbereich, für den spezialisierte und entsprechend teure Geräte notwendig sind. Ich werde einige Apps aus dem Mittelfeld vorstellen, die sich für einfache wie anspruchsvolle Vorhaben und Projekte eignen, auch auf schwächeren Tablets laufen und preisgünstig oder gratis sind. Alle Apps bieten die Möglichkeit, unterwegs zu malen, zu skizzieren, Fotos zu verfremden und die entstandenen Bilder am PC weiter bearbeiten zu können. Für PCs gibt es einige empfehlenswerte kostenlose Malprogramme, die ich bereits in einem anderen Artikel (http://medienimpulse.at/articles/view/616 vorgestellt habe.

Moving to different streams of healing praxis: A reformed missionary approach of healing in the African context

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Thinandavha D. Mashau

2016-03-01

Full Text Available There are different streams of healing praxis in Africa today, namely African traditional healing, biomedical healing and spiritual healing (which includes the more recent �touch your TV screen� healing method among others. These streams offer contemporary African people diverse alternatives with regard to healing. As much as the hegemony of Western biomedicine, as endorsed by missionaries in the past, can no longer serve as a norm in the area of healing, we can also not use the African traditional healing methods and or any other alternative presented to Africa without discernment. This suggests therefore that Reformed mission ecclesiology and missionary practitioners should critically engage the African context, worldview and culture on the matter of healing. It should also engage other forms of spiritual healing methods on offer in the African soil.Intradisciplinary and/or interdisciplinary implications: The use of an indigenous knowledge system when coming to healing in the African context, alongside Western biomedicine and other forms of spiritual healing practices, provides African people with diverse alternatives. It also poses a missiological question regarding the acceptability of such a practice within the framework of the Reformed Missionary Paradigm.Keywords: healing; praxis; Reformed; Missionary; Africa

Olhar de dirigentes sindicais sobre qualidade de vida no trabalho e mal-estar no trabalho

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Remigio Todeschini

2013-06-01

Full Text Available O objeto do artigo consistiu em conhecer as percepções de dirigentes sindicais metalúrgicos e químicos sobre o tema Qualidade de Vida no Trabalho (QVT e as fontes de mal-estar no trabalho nessas categorias profissionais. A natureza metodológica aplicada foi quantitativa e qualitativa com utilização do software Alceste. Participaram da pesquisa 81 dirigentes sindicais brasileiros (56 dirigentes químicos e 25 metalúrgicos, 85% do gênero masculino e 15% do gênero feminino oriundos das regiões sudeste, sul e nordeste do país, com aplicação do questionário via e-mail. Os resultados encontrados forneceram bases empíricas para a formulação de recomendações em Ergonomia da Atividade visando prevenir as fontes de mal-estar no trabalho. Foram reforçadas as bases teóricas da Abordagem de Ergonomia da Atividade Aplicada à Qualidade de Vida no Trabalho (EAA_QVT e o desenho de subsídios para a formulação de políticas públicas neste campo.

Analytical Characterization of the Hydrolysis of Barley Malt Macromolecules During Enzymatic Degradation Over Time Using AF4/MALS/RI.

Science.gov (United States)

Rübsam, Heinrich; Becker, Thomas; Gastl, Martina

2017-06-01

The changes on the molecular weight distribution (MWD) and particle size distribution (PSD) during hydrolysis of barley malt in isothermal mashing procedures were determined using asymmetrical flow field flow fractionation coupled to multiangle laser light scattering and refractive index (AF4/MALS/RI). Mash/trials were focused on amylolytic starch degradation. Therefore, temperatures (65, 70, and 75 °C) were selected according to α- and β-amylases range of activity. Samples were produced by triplicate, tracking amylolytic processes over time periods from 10 to 90 min in each mash/trial. AF4/MALS/RI analysis demonstrated significant differences on the values of the MWD and PSD according to the temperature/time profile used. At mashing times over 30 min at a temperature of 65 °C, when α- and β-amylase are both active, the decrease over time of the MWD and PSD was significantly higher (P < 0.005) than at 70 °C when mainly α-amylase is active. At 75 °C, also the activity of α-amylase decreased and the MWD and PSD were significantly lower (P < 0.005) than at 70 or 65 °C at any time of the procedure. The MWD and PSD of beer components influence beer palate fullness, thus AF4/ MALS/RI would be a powerful tool for breweries to adapt their technological processes to obtain beers with particular sensorial attributes. © 2017 Institute of Food Technologists®.

Pathogenicity of Phytophthora austrocedrae on Austrocedrus chilensis and its relation with mal del ciprés in Patagonia

Science.gov (United States)

A. G. Greslebin; E. M. Hansen

2010-01-01

Field observations, isolations and pathogenicity tests were performed on Austrocedrus chilensis (Cupressaceae) trees to determine the pathogenicity of Phytophthora austrocedrae and its role in the aetiology of the cypress disease mal del ciprés (MDC) in Argentina. It was found that P. austrocedrae...

Faith community as a centre of liberationist praxis in the city

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Elina Hankela

2014-11-01

Full Text Available Theologians speak of the silence of churches’ prophetic voice in the ‘new’ South Africa, whilst the country features amongst the socio-economically most unequal countries in the world, and the urban areas in particular continue to be characterised by segregation. In this context I ask: where is liberation theology? I spell out my reading of some of the recent voices in the liberationist discourse. In dialogue with these scholars I, firstly, argue for the faith community to be made a conscious centre of liberationist debates and praxis. Secondly, I do this by suggesting two theoretical building blocks (i.e. critical deconstruction and radical friendship for local faith communities that wish to grow in a liberationist fashion.

Francisco Prat Puig: His pedagogical praxis at the Universidad de Oriente

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María Cristina Hierrezuelo-Planas

2017-05-01

Full Text Available Doctor Francisco Prat Puig was one of the spanish intellectualist who sheltered in the Island of Cuba after the falling down of the Spanish Republic and in 1948 was part of the staff of professors of the recently founded Universidad de Oriente. He developed a teaching process which was centered on instruction through education and which followed the transmission and formation of values departing from his personal behavior and attitude. This took peace until his death in may, 1997. These aspect constitute one of the mastery strategies of the High Level Education Ministry of Cuba. The fact that most of his educational performance was done by the time when these aspect were not deeply applied, gives his pedagogical praxis a precursory character.

No hay mal que por bien no venga: el optimismo según Rousseau

OpenAIRE

Baranzelli, Dante A.

2004-01-01

El deísmo rousseauniano desestima la existencia del caos o del Mal general. Por el contrario, ve en el sistema del mundo un orden perfecto que obedece a la divina Providencia, identificada con la legalidad universal de la naturaleza. Mas con ello su intención no es despreciar el sufrimiento de los individuos. De hecho Rousseau reconoce y admite la presencia, e incluso la abundancia, de diversos males que afectan al hombre. ¿Acaso él mismo no es un claro ejemplo de ello?

Practical event analysis; Durchfuehrung von Ereignisanalysen in der Praxis

Energy Technology Data Exchange (ETDEWEB)

Scheuring, R. [Bayernwerk Kernenergie GmbH - Kernkraftwerk Grafenrheinfeld (Germany)

1999-04-01

The paper explains the systematic approaches and practical aspects of evaluation of NPP operating reports and implementation of identified remedial action for enhancing the safety in terms of human, organisational, and technology factors. The procedures adopted for the Grafenrheinfeld nuclear power station (KKG) serve as an example. (orig./CB) [German] Ein wichtiger Bestandteil zur Erhaltung und Fortentwicklung des Sicherheitsniveaus ist das Lernen aus der Erfahrung. Hierzu wiederum ist ein systematisches Vorgehen zur Vermeidung von Fehlern und Behebung von Schwachstellen menschlicher, technischer und organisatorischer Natur unabdingbare Voraussetzung. Die Anwendung einer umfassenden Auswertemethodik beinhaltet - die Erfassung und Informationsweitergabe externer und interner Vorkommnisse und Erfahrungen - eine systematische Analyse/Auswertung - eine konsequente Umsetzung der Abhilfemassnahmen unter Einbeziehen aller betroffenen Organisationseinheiten. Wie erfolgt die Umsetzung dieser Vorgaben in die Praxis? Im Kernkraftwerk Grafenrheinfeld (KKG) ist die Auswertung von externen und internen Betriebserfahrungen als Aufgabe im Betriebshandbuch (BHB) 'Personelle Betriebsorganisation' vorgegeben und im Detail im Sinne der Ablauforganisation im Qualitaetssicherungshandbuch in Qualitaetssicherungsanweisungen (QSA) beschrieben. (orig.)

Nurses as Antibiotic Brokers: Institutionalized Praxis in the Hospital.

Science.gov (United States)

Broom, Alex; Broom, Jennifer; Kirby, Emma; Scambler, Graham

2017-11-01

We are likely moving rapidly toward a post-antibiotic era, as a result of escalating antimicrobial resistance, rapidly declining antibiotic production and profligate overuse. Hitherto research has almost exclusively focused on doctors' prescribing, with nurses' roles in antibiotic use remaining virtually invisible. Drawing on interviews with 30 nurses, we focus on nurses as brokers of doctors' antibiotic decisions, nursing capacity to challenge doctors' decisions, and, "back stage" strategies for circumnavigating organizational constraints. We argue that nurses occupy an essential and conscious position as brokers within the hospital; a subject position that is not neutral, facilitates (short-term) cohesion, and involves the pursuit of particular (preferred) nursing outcomes. Illustrating how authority can be diffuse, mediated by institutionalized praxis, and how professionals evade attempts to govern their practice, we challenge the reification of physician prescribing power, arguing that it may work against the utilization of nurses as important stakeholders in the future of antibiotics.

Lower expression of CADM1 and higher expression of MAL in Merkel cell carcinomas are associated with Merkel cell polyomavirus infection and better prognosis.

Science.gov (United States)

Iwasaki, Takeshi; Matsushita, Michiko; Nonaka, Daisuke; Nagata, Keiko; Kato, Masako; Kuwamoto, Satoshi; Murakami, Ichiro; Hayashi, Kazuhiko

2016-02-01

Merkel cell carcinoma (MCC) is a clinically aggressive neuroendocrine skin cancer; 80% of the cases are associated with the Merkel cell polyomavirus (MCPyV). We previously reported that MCPyV-negative MCCs have more irregular nuclei with abundant cytoplasm and significantly unfavorable outcomes than do MCPyV-positive MCCs. These results suggest that some cell adhesion or structural stabilization molecules are differently expressed depending on MCPyV infection status. Thus, we investigated the association of prognosis or MCPyV infection status in MCCs with cell adhesion molecule 1 (CADM1)/differentially expressed in adenocarcinoma of the lung protein 1 (DAL-1)/membrane protein, palmitoylated 3 (MPP3) tripartite complex and mal T-cell differentiation protein (MAL) expression, which play important roles in cell adhesion and oncogenesis and are related to cancer outcomes in various malignancies, to elucidate the role of these molecules. We analyzed the pathological and molecular characteristics of 26 MCPyV-positive and 15 MCPyV-negative MCCs. Univariate Cox regression analysis showed that advanced age (hazard ratio [HR], 8.249; P = .007) and high CADM1 expression (HR, 5.214; P = .012) were significantly unfavorable overall survival parameters, whereas MCPyV infection (HR, 0.043, P Merkel cells expressed DAL-1 and MAL but not CADM1. This study revealed that MCPyV-negative MCCs significantly expressed higher CADM1 and lower MAL than MCPyV-positive MCCs; these expression levels were markedly related to unfavorable outcomes. These data will give us important insights to develop novel molecular target therapies for MCCs. Copyright © 2015 Elsevier Inc. All rights reserved.

Theoretical Characteristics of Metalloporphyrins (OEP) M (CH 3 ) (M=Al, Ga, In and Tl)

OpenAIRE

Lepetit , M.B.; Kabbaj , O.K.; Zrineh , A.

2017-01-01

International audience; A theoretical study of metalloporphyrins molecules (OEP) M (CH 3) (M=Al, Ga, In and Tl) are brought to a few experimental data and to give background for future development of these complexes. The Quantum Chemistry Program (ORCA) program package based on Density Functional Theory (DFT) and Time-dependent Density Functional Theory (TDDFT) for transitions at the B3LYP level with ANO 2ζ+P base was used for calculations and determination of structural properties, electroni...

Synthesis, crystal structure and magnetic properties of [Cu(mal(abpt(H2O].3/2H2O and [Cu2(sq(abpt 2].2H2O (mal = malonate, sq = squarate, abpt = 4-amino-3,5-di-2-pyridyl-4H-1,2,4 triazole

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Eno A. Ededet

2011-04-01

Full Text Available Two new mixed-ligand complexes of formula [Cu(mal(abpt(H2O].3/2H2O (1 and [Cu2(sq(abpt2].2H2O (2 [mal = malonate, abpt = 4-amino-3,5-di-2-pyridyl-4H-1,2,4 triazole and sq = squarate], have been prepared and characterized by X-ray crystal structure determination and magnetic studies. Complex 1 crystallizes in the monoclinic system, space group C2/c, with a = 14.0086(2 Å, b = 10.0980(2 Å, c = 25.630(4 Å; β = 97.5900(10 o, and Z = 8. Complex 2 crystallizes in the triclinic system, space group P-1 with a = 7.5696(15 Å, b = 8.4697(17 Å, c = 11.049(2 Å; β = 93.00(3o, α = 96.98(3, γ = 90.111(3 and Z = 1. Complex 1 consist of a neutral mononuclear [Cu(mal(abpt(H2O] unit and water molecule of crystallization in a distorted square pyramidal coordination sphere, while complex 2 is viewed as being made up of [Cu(sq(abpt2] units with the squarato ligand bridging the two copper(II cations. Variable temperature magnetic behaviour of the complexes reveals the existence of weak antiferromagnetic interaction for complex 1 and weak ferromagnetic intrachain interaction for complex 2.

The Systemic Theory of Living Systems. Part IV: Systemic Medicine—The Praxis

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José A. Olalde Rangel

2005-01-01

Full Text Available This fourth lecture illustrates the praxis and results of Systemic Medicine (SM in various therapeutic applications. SM's success has made it popular throughout Venezuela and Puerto Rico. The treatment of over 300 000 patients by 150 orthodox MD's, trained and qualified in SM, in 35 medical establishments with above average results corroborate its effectiveness as an eCAM in chronic degenerative diseases. Herein we provide a synopsis of results obtained in four such pathologies—the journal's necessary space restrictions somewhat limiting content—as well as clinical and photographic evidence. The validity of any medical theory is substantiated by its degree of effectivity and success. The workability of evidence-based SM corroborates Systemic Theory's transcendence.

PENGARUH KEBUDAYAAN KONTEMPORER DALAM PERANCANGAN ARSITEKTUR MAL

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Freddy H. Istanto

2000-01-01

Full Text Available Market is traditionally known as the place where the seller and the buyers meet. In its development, it grows to be big shopping centers and even malls. Along with it, the concept of market has also changed within this building. It is not only the place where the transaction between the sellers and the buyers happen but also it expands to be the one where each person has turned to be the "player" in the nowadays "cultural-theatre". Being the designers, the architect is challenged to respond the changing pattern in the society by making use of the building. Abstract in Bahasa Indonesia : Pasar dikenal sebagai tempat dimana penjual dan pembeli bertemu. Dalam perkembangan lebih lanjut muncul pusat-pusat pertokoan yang sangat besar sampai hadirnya shopping-mall. Di dalam bangunan inilah konsep pasar secara tradisional telah berkembang, tidak saja tempat transaksi antara penjual dan pembeli, tetapi telah melebar menjadi tempat dimana setiap individu telah menjadi "pemain" di dalam sebuah teater kebudayaan masa kini. Arsitek sebagai perancang bangunan harus menyikapi perubahan-perubahan perilaku yang terjadi di masyarakat dalam menggunakan bangunannya. Kata kunci: kebudayaan kontemporer, arsitek, arsitektur mal, kebudayaan milenium tiga.

malERA: An updated research agenda for basic science and enabling technologies in malaria elimination and eradication

Science.gov (United States)

2017-01-01

Basic science holds enormous power for revealing the biological mechanisms of disease and, in turn, paving the way toward new, effective interventions. Recognizing this power, the 2011 Research Agenda for Malaria Eradication included key priorities in fundamental research that, if attained, could help accelerate progress toward disease elimination and eradication. The Malaria Eradication Research Agenda (malERA) Consultative Panel on Basic Science and Enabling Technologies reviewed the progress, continuing challenges, and major opportunities for future research. The recommendations come from a literature of published and unpublished materials and the deliberations of the malERA Refresh Consultative Panel. These areas span multiple aspects of the Plasmodium life cycle in both the human host and the Anopheles vector and include critical, unanswered questions about parasite transmission, human infection in the liver, asexual-stage biology, and malaria persistence. We believe an integrated approach encompassing human immunology, parasitology, and entomology, and harnessing new and emerging biomedical technologies offers the best path toward addressing these questions and, ultimately, lowering the worldwide burden of malaria. PMID:29190277

Fernandez osteotomy of radio distal with mal united fracture

International Nuclear Information System (INIS)

Garcia Herrera, Alvaro; Bocanegra, Sergio; Suarez, Fabio

2003-01-01

We review prospectively our experience in the military hospital in Bogota, Colombia, with the opening-wedge osteotomy for the treatment of a mal united fracture of the distal end of the radius in fifty-six consecutive patients from 1990 to 2002. The indications for operation were pain predominantly in the radio-ulnar joint and functional limitation with grip strength loss. Preoperative radiographs revealed an average ulnar inclination of 14 degrees, an average ulnar variance of four millimeters, and increased dorsal tilt (colles deformity) that averaged 28 degrees. All patients had limited function. The average grip strength was a force of fifteen kilograms compared with a force of thirty-one kilograms in the contralateral hand. Postoperatively, all of the patients had substantial improvement in function, relief of pain and grip strength increased. The functional results were rated as very good in eleven patients, good in thirty-six, fair in nine

Spiritual and ethical transformational leadership: Critical discourse analysis within a practical theology praxis

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Gordon E. Dames

2014-06-01

Full Text Available The objective of this article is to focus renewed attention on ethics in contemporary dialogue through value-based leadership. This is done with reference to the value of meaning in social research and critical discourse analysis within a framework of leadership discourse praxis. Discourse constructs, such as dominance and power, are analysed in the (reproduction of oppression, injustice and inequality. The objective is to analyse the way in which human ideas and the actions of powerful and dominant leadership elites are influencing and dominating ethical and/or unethical public enactments. The hypothesis is that ethical discourse enactments (practices could foster authentic ethical and transformational leadership.

The (Mal)Practice of Dowry in Contemporary India. A Challenge to Marriage and Family Ministry

OpenAIRE

Jainus Xavier, Nixen Raj; Jainus Xavier, Nixen Raj; Knieps-Port le Roi, Thomas

2012-01-01

The author explores the (mal)practice of dowry in contemporary India and the challenge it presents to marriage and family ministry. He explains how originally harmless and well-intended dowry customs changed under the influence of historical circumstances that turned them into a business-like family strategy aimed at rising families’ social status, wealth and power. This evolution had dramatic consequences for Indian marriage and family life and especially for women. Dowry-related violence an...

ACCUMULATION OF POLYHYDROXYALKANOIC ACIDS BY AZOTOBACTER CHROOCOCCUM MAL-201 FROM ORGANIC WASTE

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Soma Pal Saha

2013-08-01

Full Text Available Azotobacter chroococcum MAL-201 (MTCC 3853, a free-living nitrogen-fixing bacterium accumulated intracellular poly(3-hydroxybutyric acid [P(3HB] accounting 69% of cell dry weight (CDW when grown in nitrogrn-free Stockdale medium containing 2% (w/v glucose. It also produced copolymer of poly(3-hydroxybutyrate co-3-hydroxyvalerate [P(3HB-co-3HV] using glucose as primary carbon source and valerate cas cosubstrate. To make the polymer production cost effective four types of waste material of different origin were tested for growth and polymer production. Stockdale medium supplemented with 1% (w/v waste materials failed to yield good growth and polymer accumulation. Two–step cultivation was adopted for better growth and enhanced polymer accumulation. The candy factory waste was most suitable for synthesis of P(3HB accounting 17.8 and 40.58% using single and two-step cultivation conditions respectively. Wastes of domestic and poultry origin produced P(3HB-co-3HV with 3HV content 28.8 and 21.5 mol% respectively in two-step cultivation. Increase concentration of these wastes resulted in further upliftment of 3HV content of polymer with reduced growth and polymer accumulation. However, at optimum incubation the strain MAL-201 cells accumulated P(3HB 48.5% of CDW (at 40h from candy factory waste and P(3HB-co-3HV 24.75 % of CDW with 3HV 34.65 mol % from domestic waste. Intrinsic viscosity, molecular weight and thermal degradation of the polymers accumulated in the cells grown in glucose, glucose with valerate and glucose with waste were compared.

Structural distortions in Sr3-xAxMO4F (A=Ca, Ba; M=Al, Ga, In) anti-Perovskites and corresponding changes in photoluminescence

International Nuclear Information System (INIS)

Sullivan, Eirin; Avdeev, Maxim; Vogt, Thomas

2012-01-01

The ordered oxyfluoride family Sr 3 − x A x MO 4 F (A=Ca, Ba and M=Al, Ga) has formed the basis of several new inorganic phosphors, and shows great potential for use in phosphor-conversion LED lamp devices. This study examines the correlation between subtle structural changes and photoluminescent behaviour in some of these materials. In order to ascertain whether cation charge compensation has any influence on structure and subsequent photoluminescent behaviour, a comparison was carried out between phases with the nominal compositions Sr 2.975 Ce 0.025 AlO 4 F and Sr 2.95 Ce 0.025 Na 0.025 AlO 4 F using structural characterisation based upon high-resolution neutron powder diffraction (NPD) data. Additionally, NPD data has been used to elucidate the role of different M cations in these materials, using Sr 2.25 Ba 0.6 Eu 0.1 M 0.95 In 0.05 O 4−α F 1−δ (M=Al, Ga) to determine the effect M cation size has on structure and photoluminescent properties. - Graphical abstract: The structure of Sr3-xAxMO4F (A=Ca, Ba and M=Al, Ga) and excitation and emission spectra for Sr 2.25 Ba 0.6 Eu 0.1 Ga 0.95 In 0.05 O 4−α F 1−δ . Highlights: ► Correlation between structural changes and photoluminescence in Sr 3−x A x MO 4 F (A=Ca, Ba, M=Al, Ga). ► Comparison of Sr 2.975 Ce 0.025 AlO 4 F and Sr 2.95 Ce 0.025 Na 0.025 AlO 4 F using high-resolution NPD. ► Study of the effect of cation charge-compensation on structure and photoluminescent behaviour. ► Examination of high-resolution NPD data for Sr 2.25 Ba 0.6 Eu 0.1 M 0.95 In 0.05 O 4−α F 1−δ (M=Al, Ga). ► Determination of the effect M cation size has on structure and photoluminescent properties.

Troubling practices of control: re-visiting Hannah Arendt's ideas of human action as praxis of the unpredictable.

Science.gov (United States)

Kohlen, Helen

2015-07-01

In this article, Hannah Arendt's concept of action will be used to problematize current transformations of the health care sector and examine some responses by ethicists in light of those transformations. The sphere of human interaction that should typify health care work is identified as an action of unpredictable praxis in contrast to controllable procedures and techniques which increasingly take place in the health care sector. © 2015 John Wiley & Sons Ltd.

First successful reduction of clinical allergenicity of food by genetic modification: Mal d 1-silenced apples cause fewer allergy symptoms than the wild-type cultivar

DEFF Research Database (Denmark)

Dubois, A. E. J.; Pagliarani, G.; Brouwer, R. M.

2015-01-01

BACKGROUND: Genetic modification of allergenic foods such as apple has the potential to reduce their clinical allergenicity, but this has never been studied by oral challenges in allergic individuals. METHODS: We performed oral food challenges in 21 apple-allergic individuals with Elstar apples...... which had undergone gene silencing of the major allergen of apple, Mal d 1, by RNA interference. Downregulation of Mal d 1 gene expression in the apples was verified by qRT-PCR. Clinical responses to the genetically modified apples were compared to those seen with the wild-type Elstar using a visual...

CADM1, MAL and miR124-2 methylation analysis in cervical scrapes to detect cervical and endometrial cancer

NARCIS (Netherlands)

De Strooper, Lise M. A.; van Zummeren, Marjolein; Steenbergen, Renske D. M.; Bleeker, Maaike C. G.; Hesselink, Albertus T.; Schuurs-Wisman, G. Bea A.; Snijders, Peter J. F.; Heideman, Danielle A. M.; Meijer, Chris J. L. M.

2014-01-01

Aims Gene promoter hypermethylation is recognised as an essential early step in carcinogenesis, indicating important application areas for DNA methylation analysis in early cancer detection. The current study was set out to assess the performance of CADM1, MAL and miR124-2 methylation analysis in

Geography, population, demography, socioeconomic, anthropometry, and environmental status in the MAL-ED cohort and case-control study Sites in Fortaleza, Ceará, Brazil.

Science.gov (United States)

Lima, Aldo A M; Oriá, Reinaldo B; Soares, Alberto M; Filho, José Q; de Sousa, Francisco; Abreu, Cláudia B; Bindá, Alexandre; Lima, Ila; Quetz, Josiane; Moraes, Milena; Maciel, Bruna; Costa, Hilda; Leite, Alvaro M; Lima, Noélia L; Mota, Francisco S; Di Moura, Alessandra; Scharf, Rebecca; Barrett, Leah; Guerrant, Richard L

2014-11-01

The Etiology, Risk Factors and Interactions of Enteric Infections and Malnutrition and the Consequences for Child Health and Development (MAL-ED) cohort in the study's Fortaleza, Brazil, catchment area has a population of approximately 82 300 inhabitants. Most of the households (87%) have access to clean water, 98% have electricity, and 69% have access to improved toilet/sanitation. Most childbirths occur at the hospital, and the under-5 mortality rate is 20 per 1000 live births. The MAL-ED case-control study population, identified through the Institute for the Promotion of Nutrition and Human Development (IPREDE), serves 600 000 inhabitants from areas totaling about 42% of the city of Fortaleza. IPREDE receives referrals from throughout the state of Ceará for infant nutrition, and provides services including teaching activities and the training of graduate students and health professionals, while supporting research projects on child nutrition and health. In this article, we describe the geographic, demographic, socioeconomic, anthropometric, and environmental status of the MAL-ED cohort and case-control study populations in Fortaleza, Brazil. © The Author 2014. Published by Oxford University Press on behalf of the Infectious Diseases Society of America. All rights reserved. For Permissions, please e-mail: journals.permissions@oup.com.

Theoria cum Praxi? The (In- Compatibility of Demands in Science and Business World

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Monika Kritzmöller

2004-05-01

Full Text Available The necessity for co-operation between (scientific theory and (management praxis is apparent more than ever. There are countless parallels in the goals and objectives of social and marketing research, for example, learning more about communities—respectively customers—and explaining their behavior. Extending social research services to businesses can create synergistic effects. On the one hand, the scientists can benefit financially in dimensions not feasible at universities and have a fruitful dialogue with business practitioners. On the other hand, the business management have access to the latest scientific results of high quality before these results are available to competitors as official publications. These opportunities and advantages can no longer permit a prejudice-based, mutual ideological rejection, which can still be found in both spheres. In the course of my "Habilitation" at the University of St. Gallen (Switzerland, I created a successful method for combining theory with practice. I developed a sociological theory of social structure, which can be put into practice in order to analyze and comprehend the behavior of target groups in marketing. I co-operated with selected furniture manufacturers and received advanced payments during the entire period of my research. In return, these manufacturers received my consulting services. I applied the research findings directly to their business demands after the end of my project. On the one hand, this procedure requires that a scientist is experienced in business affairs and has the ability and readiness for transferring scientific results into every-day practice. On the other hand, management needs to give up short-term thinking of "KISS" (keep it short and simple and care about understanding things instead of merely describing them. My co-operation in the project and the implementation of "theoria cum praxi" approach was a positive experience, which I will continue using in future

MosquitoMap and the Mal-area calculator: new web tools to relate mosquito species distribution with vector borne disease.

Science.gov (United States)

Foley, Desmond H; Wilkerson, Richard C; Birney, Ian; Harrison, Stanley; Christensen, Jamie; Rueda, Leopoldo M

2010-02-18

Mosquitoes are important vectors of diseases but, in spite of various mosquito faunistic surveys globally, there is a need for a spatial online database of mosquito collection data and distribution summaries. Such a resource could provide entomologists with the results of previous mosquito surveys, and vector disease control workers, preventative medicine practitioners, and health planners with information relating mosquito distribution to vector-borne disease risk. A web application called MosquitoMap was constructed comprising mosquito collection point data stored in an ArcGIS 9.3 Server/SQL geodatabase that includes administrative area and vector species x country lookup tables. In addition to the layer containing mosquito collection points, other map layers were made available including environmental, and vector and pathogen/disease distribution layers. An application within MosquitoMap called the Mal-area calculator (MAC) was constructed to quantify the area of overlap, for any area of interest, of vector, human, and disease distribution models. Data standards for mosquito records were developed for MosquitoMap. MosquitoMap is a public domain web resource that maps and compares georeferenced mosquito collection points to other spatial information, in a geographical information system setting. The MAC quantifies the Mal-area, i.e. the area where it is theoretically possible for vector-borne disease transmission to occur, thus providing a useful decision tool where other disease information is limited. The Mal-area approach emphasizes the independent but cumulative contribution to disease risk of the vector species predicted present. MosquitoMap adds value to, and makes accessible, the results of past collecting efforts, as well as providing a template for other arthropod spatial databases.

Pedagogical Praxis Surrounding the Integration of Photography, Visual Literacy, Digital Literacy, and Educational Technology into Business Education Classrooms: A Focus Group Study

Science.gov (United States)

Schlosser, Peter Allen

2010-01-01

This paper reports on an investigation into how Marketing and Business Education Teachers utilize and integrate educational technology into curriculum through the use of photography. The ontology of this visual, technological, and language interface is explored with an eye toward visual literacy, digital literacy, and pedagogical praxis, focusing…

Avaliação de genótipos tetraploides de bananeira cultivados em área infestada pelo agente causal do mal-do-Panamá

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Sebastião de Oliveira e Silva

2011-03-01

Full Text Available O mal-do-Panamá é uma doença que causa grandes prejuízos à bananicultura no Brasil, uma vez que as principais cultivares em uso são suscetíveis ao Fusarium. Este trabalho teve como objetivos avaliar características agronômicas e resistência ao mal-do-Panamá de híbridos tetraploides de bananeira. O experimento foi conduzido no campo experimental da Embrapa Mandioca e Fruticultura Tropical, em delineamento casualizado, com 14 tratamentos e 10 repetições, nos anos de 2000 e 2001. Foram avaliados 14 tetraploides (FHIA-03, PV03-44, PC42-01, PV42-53, PV42-68, PV42-81, PV42-85, PV42-129, PV42-142, PV42-143, SH3640, ST12-31, ST42-08 e YB42-21 e a cultivar Maçã, usada como testemunha. Avaliaram-se as características altura da planta (m e diâmetro do pseudocaule (cm a 30 cm do solo, peso da massa do cacho (kg, penca (kg e fruto (g, número de pencas por cacho, de frutos por penca e de dias do florescimento à colheita, e a incidência do mal-do-Panamá. As médias dos genótipos foram agrupadas pelo teste de Scott e Knott, a 5% de probabilidade. Observa-se uma ampla variação genética nos caracteres avaliados. Os genótipos FHIA 03, ST12-31, SH3640, PV42-142, PV42-53 e PV42-68apresentam boas características agronômicas e resistência ao mal-do-Panamá.

PERTANGGUNGAN JAWAB PIDANA PEJABAT ATAS TINDAKAN MAL-ADMINISTRASI DALAM PENERBITAN IZIN DI BIDANG LINGKUNGAN

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Ahmad Basuki

2011-09-01

Full Text Available The democratic strengthen is very influencing to the demand of good governance in managing the government. One of the positive demand is it has been adopted the principle of accountability of the constitution of protection and management of environment for official functionary on the act of mal administration in establishing permit of environment field, Based on the principle community who become sacrifice of pollution of environment can appeal the legal permit and the responsibility of criminal case towards the official functionary of disadvantages they have got.

Malaria infection and the anthropological evolution Infecção por Malária e evolução antropológica

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Sergio Sabbatani

2010-03-01

malária exerceu papel biológico chave, influenciando até o desenvolvimento antropológico. Os Plasmódios causadores da malária desenvolveram dois tipos de evolução, segundo um ponto de vista biológico, e filogenético. Em particular, os Plasmódios vivax, malariae, e ovale poderiam ter coevoluído com a espécie humana ou ter atingido esta durante as fases mais antigas da evolução do gênero HOMO. Por outro lado, o Plasmódio falciparum teria sido transmitido aos humanos por macacos num período mais recente, provavelmente entre o fim da Idade Mesolítica e o início da Neolítica. Os Autores mostram evidências biomoleculares, tanto diretas como indiretas, de infecção por malária, observada em indivíduos enterrados, reportando ao Mundo Antigo, e trazidas à luz no decorrer de escavações arqueológicas em alguns sítios relevantes Mediterrâneos. Nesta revisão da literatura, os autores organizam evidências modernas. Confirmam o papel da malária ao afetar a evolução das populações no Mediterrâneo. As pessoas que moram nas várias regiões do Mediterrâneo foram progressivamente influenciadas pela malária, ao longo do avanço desta doença. Além disso, as populações afetadas desenvolveram adaptações culturais, alimentares, e de comportamento, contribuindo para uma redução no risco da doença. Entretanto, pode ser que ambas modificações (as biológicas e as dos hábitos usadas pelos Plasmódios da malária, favoreceram a emergência de grupos de pessoas com maior resistência contra a malária. Todos estes fatores considerados reduziram o impacto demográfico, influenciando de uma maneira favorável o desenvolvimento em geral, e o crescimento da civilização.

Gestalt y Heterodoxia: un cambio proactivo aplicable en la praxis investigativa universitaria

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Beatriz Carolina Carvajal

2017-01-01

Full Text Available La pesquisa que da origen a este artículo está soportada en la propia experiencia en el área de sistemas humanos, específica - mente en el estudio del quehacer investigativo y la gestión del conocimiento universitario latinoamericano. De esa experien - cia previa, se desprende la siguiente premisa: el contexto cam - biante exige a las universidades respuestas basadas en un en - foque vanguardista para comprender e interpretar los hechos sociales y naturales. El objetivo que fundamenta este reporte es proponer estrategias de acción creativas en el quehacer in- vestigativo para el reciclaje de los métodos de investigación, y así, generar una praxis proactiva, gestáltica y heterodoxa. Los métodos aplicados fueron la investigación documental y la re- flexión hermenéutica. Se tomó una muestra intencional y se rea - lizaron entrevistas a informantes clave provenientes de diversas universidades e institutos de investigación latinoamericanos y que están afiliados a una de estas redes: 1 Red para la Difusión Científica y Humanística Heterodoxias y 2 Red de Estudios Organizacionales en América Latina, el Caribe e Iberoamérica. Como soporte teórico se reflexiona con base en los constructos de Gestalt (Perls, 1977; Moreau, 1999; Vázquez-Badin, 2010 y de Heterodoxia (Savater y Villena, 1989; Carvajal, 2010a. Se concluye que el cambio proactivo aplicable en la praxis inves - tigativa universitaria supone la responsabilidad, el compromiso y el liderazgo del investigador universitario como agente trans - formacional, lo cual conlleva la revalorización de la vinculación universidad-sector socio productivo y demanda la innovación, la creatividad y la recreación permanentemente de los métodos de investigación usados para comprender e interpretar la reali- dad desde la heterodoxia y la totalidad.

Bibliothekarische Berufsethik in der Praxis – Ergebnisse eines Studienprojekts aus Deutschland und Großbritannien

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Jens Boye

2011-10-01

Full Text Available Sowohl in Deutschland als auch in Großbritannien existieren seit einigen Jahren Grundsatzpapiere zur Berufsethik im Informations- und Bibliotheksbereich. Neben der bloßen Existenz derartiger Kodizes stellt sich die Frage, welche Relevanz diese Dokumente in der beruflichen Praxis haben. Dieser Frage wurde im Rahmen einer Team-Projektarbeit an der FH Köln nachgegangen. Mithilfe eines standardisierten Fragebogens wurden deutsche Bibliotheksleitungen zu der Thematik befragt. In Großbritannien wurde ein Interview mit Paul Sturges geführt, darüber hinaus erfolgte eine Analyse der Online-Angebote von CILIP, insbesondere des Information Ethics Blog.

SUPERVISION IMPLEMENTATION IN MANAGEMENT QUALITY: AN ATTEMPT TO IMPROVE THE QUALITY OF LEARNING AT MADRASAH ALIYAH DARUL A’MAL METRO

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Subandi Subandi

2016-03-01

Full Text Available The primary purpose of this qualitative study is to identify and analyze supervision by implementing management quality to improve the quality of learning at Madrasah Aliyah Darul A’mal Metro, Lampung. The quality of management implementation is elaborated in the steps of assurance of learning quality. Two instruments, which consist of observation and questionnaire, were used in this study of which each instrument was analyzed based the deductive framework. The results of this study from each instrument revealed four steps of assurance of learning quality, among others (1 by socializing academic supervision program and its advantages to all stake holders, and (2 by implementing stages of assurance through academic supervision by the principals of Madrasah Aliyah Darul A’mal and supervisor, (3 performing supervision that is equipped with valid instrument to measure learning success, (4 performing the follow-up program by clinical and group discussion to provide appropriate model of performance.

"Con Café, Compañerismo, y Calidad": Latina Women Fashioning a Writing Group into a Space of Praxis and Belonging

Science.gov (United States)

Hurtig, Janise

2016-01-01

This article explores the spatial practices through which a group of Mexican immigrant women, participants in a school-based writing workshop I facilitated for four years, molded and gave meaning to our weekly writing routine to foster inclusivity as the basis for collective teaching and learning--creating what I refer to as a space of praxis and…

malERA: An updated research agenda for malaria elimination and eradication.

Science.gov (United States)

Rabinovich, Regina N; Drakeley, Chris; Djimde, Abdoulaye A; Hall, B Fenton; Hay, Simon I; Hemingway, Janet; Kaslow, David C; Noor, Abdisalan; Okumu, Fredros; Steketee, Richard; Tanner, Marcel; Wells, Timothy N C; Whittaker, Maxine A; Winzeler, Elizabeth A; Wirth, Dyann F; Whitfield, Kate; Alonso, Pedro L

2017-11-01

Achieving a malaria-free world presents exciting scientific challenges as well as overwhelming health, equity, and economic benefits. WHO and countries are setting ambitious goals for reducing the burden and eliminating malaria through the "Global Technical Strategy" and 21 countries are aiming to eliminate malaria by 2020. The commitment to achieve these targets should be celebrated. However, the need for innovation to achieve these goals, sustain elimination, and free the world of malaria is greater than ever. Over 180 experts across multiple disciplines are engaged in the Malaria Eradication Research Agenda (malERA) Refresh process to address problems that need to be solved. The result is a research and development agenda to accelerate malaria elimination and, in the longer term, transform the malaria community's ability to eradicate it globally.

malERA: An updated research agenda for malaria elimination and eradication.

Directory of Open Access Journals (Sweden)

Regina N Rabinovich

2017-11-01

Full Text Available Achieving a malaria-free world presents exciting scientific challenges as well as overwhelming health, equity, and economic benefits. WHO and countries are setting ambitious goals for reducing the burden and eliminating malaria through the "Global Technical Strategy" and 21 countries are aiming to eliminate malaria by 2020. The commitment to achieve these targets should be celebrated. However, the need for innovation to achieve these goals, sustain elimination, and free the world of malaria is greater than ever. Over 180 experts across multiple disciplines are engaged in the Malaria Eradication Research Agenda (malERA Refresh process to address problems that need to be solved. The result is a research and development agenda to accelerate malaria elimination and, in the longer term, transform the malaria community's ability to eradicate it globally.

Revising Translations

DEFF Research Database (Denmark)

Rasmussen, Kirsten Wølch; Schjoldager, Anne

2011-01-01

The paper explains the theoretical background and findings of an empirical study of revision policies, using Denmark as a case in point. After an overview of important definitions, types and parameters, the paper explains the methods and data gathered from a questionnaire survey and an interview...... survey. Results clearly show that most translation companies regard both unilingual and comparative revisions as essential components of professional quality assurance. Data indicate that revision is rarely fully comparative, as the preferred procedure seems to be a unilingual revision followed by a more...... or less comparative rereading. Though questionnaire data seem to indicate that translation companies use linguistic correctness and presentation as the only revision parameters, interview data reveal that textual and communicative aspects are also considered. Generally speaking, revision is not carried...

Gross Mal distribution Identification and Effect of Inlet Distributor on the Phase Holdup in a Trickle Bed Reactor Using Gamma-Ray Densitometry (GRD)

International Nuclear Information System (INIS)

Mohd Fitri Abdul Rahman; Alexander, V.; Al-Dahhan, M.

2016-01-01

Local liquid and gas mal distribution and their holdups in a packed column are difficult to identify due to multiphase properties and other design factors. Good liquid and gas flow distribution important to determine to get high performance of Trickle Bed Reactor (TBR). Gross mal distribution indicates some faulty or bad flow distribution of liquid and gas. In this work, gross mal distribution of phases has been identified using Gamma Ray Densitometry (GRD) technique with three types of inlet distributors (single inlet towards the wall, single inlet at the center, and proper shower) by measuring line average diameter profile of phases (Liquid, Gas, and Solids) holdups. Gamma-ray densitometry is a non-invasive technique which can be implemented at the laboratory, pilot plant, and industrial scales reactors. Experiments were performed on 0.14 m diameter reactor made of Plexiglas filled with 0.003 m glass bead which acts as the solid. The superficial velocities for both gas and liquid were in the range 0.03 m/s to 0.27 m/s and 0.004 m/s to 0.014 m/s respectively. Proper shower distributor showed early liquid spreading than compared with other distributors. The effect of superficial gas velocity on liquid spread was seen to be non-significant, and liquid distribution is found to be almost uniform at the center region of the catalyst bed. (author)

A computational fluid dynamics and effectiveness-NTU based co-simulation approach for flow mal-distribution analysis in microchannel heat exchanger headers

International Nuclear Information System (INIS)

Huang, Long; Lee, Moon Soo; Saleh, Khaled; Aute, Vikrant; Radermacher, Reinhard

2014-01-01

Refrigerant flow mal-distribution is a practical challenge in most microchannel heat exchangers (MCHXs) applications. Geometry design, uneven heat transfer and pressure drop in the different microchannel tubes are three main reasons leading to the flow mal-distribution. To efficiently and accurately account for these three effects, a new MCHX co-simulation approach is proposed in this paper. The proposed approach combines a detailed header simulation based on computational fluid dynamics (CFD) and a robust effectiveness-based finite volume tube-side heat transfer and refrigerant flow modeling tool. The co-simulation concept is demonstrated on a ten-tube MCHX case study. Gravity effect and uneven airflow effect were numerically analyzed using both water and condensing R134a as the working fluids. The approach was validated against experimental data for an automotive R134a condenser. The inlet header was cut open after the experimental data had been collected. The detailed header geometry was reproduced using the proposed CFD header model. Good prediction accuracy was achieved compared to the experimental data. The presented co-simulation approach is capable of predicting detailed refrigerant flow behavior while accurately predicts the overall heat exchanger performance. - Highlights: •MCHX header flow distribution is analyzed by a co-simulation approach. •The proposed method is capable of simulating both single-phase and two-phase flow. •An actual header geometry is reproduced in the CFD header model. •The modeling work is experimentally validated with good accuracy. •Gravity effect and air side mal-distribution are accounted for

An ecosystem approach to malaria control in an urban setting Uma abordagem ecossistêmica ao controle da malária em contexto urbano

Directory of Open Access Journals (Sweden)

Gabriel Carrasquilla

2001-01-01

Full Text Available We conducted a research project aimed at strengthening local government and the community for a sustainable malaria control strategy. The project began with a baseline diagnosis of malaria prevalence, a KAP survey, entomology, and health services delivery, after which an epidemiological study was performed to identify risk factors associated with malaria, thereafter used to plan intervention measures. A program evaluation was conducted five years later. By using an ecosystem approach to reanalyze data, this paper discusses how malaria arises from a complex interaction of cultural, economic, ecological, social, and individual factors. Intervention measures require an intersectorial and transdisciplinary approach that does not exist at the moment. Health sector leadership is limited, and there is no true community participation. Implications for research, including the use of qualitative and quantitative methods, study design, and complexity of data analysis are discussed. Finally, implications for malaria control are discussed, stressing the differences between the ecosystem and integrated disease control approaches.Os autores implementaram um projeto de pesquisa voltado ao fortalecimento do governo local e da comunidade com vistas à estratégia sustentável de controle da malária. O projeto iniciou com diagnóstico prévio, incluindo prevalência da malária, entomologia, KAP (conhecimentos, atitudes e práticas e oferta de serviços de saúde; a seguir, realizou-se inquérito epidemiológico para identificar fatores de risco associados à malária e a escolha de medidas de intervenção adequadas. O programa foi avaliado após cinco anos. Ao adotar a abordagem ecossistêmica para re-analisar os dados, o artigo discute como a malária surge a partir da interação complexa entre fatores culturais, econômicos, ecológicos, sociais e individuais. Medidas de intervenção exigem abordagem intersetorial e transdisciplinar ainda não existente. A

Reconciliación de Malí; mayo en Kidal, inflexión en la segunda fase del proceso

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Juan Carlos Castilla

2015-01-01

Full Text Available La reconciliación es uno de los retos de la consolidación de la paz. El ejercicio de la soberanía por parte de las instituciones locales, puede originar diferencias con las organizaciones internacionales durante la transformación del conflicto. El desafío es coordinar estrategias y medidas en el tiempo. El proceso de reconciliación comenzó en Malí con un gobierno de transición. Durante el año 2014, el gobierno ha tratado de impulsar el proceso, en un contexto en el que se han reproducido los enfrentamientos tribales, se han dado nuevos choques entre el MNLA y las Fuerzas Armadas malíes, y dónde sigue influyendo la actividad terrorista yihadista. IBK se refirió a aspectos fundamentales para el futuro inmediato del proceso tras los acontecimientos de mayo en Kidal. Tras estos acontecimientos, las negociaciones de paz se desarrollan con la mediación argelina. La complementariedad entre la justicia nacional y la internacional será una de las claves, lo que a su vez puede interrelacionar con la potencial re-integración futura de excombatientes.

Revision total hip arthoplasty: factors associated with re-revision surgery.

Science.gov (United States)

Khatod, Monti; Cafri, Guy; Inacio, Maria C S; Schepps, Alan L; Paxton, Elizabeth W; Bini, Stefano A

2015-03-04

The survivorship of implants after revision total hip arthroplasty and risk factors associated with re-revision are not well defined. We evaluated the re-revision rate with use of the institutional total joint replacement registry. The purpose of this study was to determine patient, implant, and surgeon factors associated with re-revision total hip arthroplasty. A retrospective cohort study was conducted. The total joint replacement registry was used to identify patients who had undergone revision total hip arthroplasty for aseptic reasons from April 1, 2001, to December 31, 2010. The end point of interest was re-revision total hip arthroplasty. Risk factors evaluated for re-revision total hip arthroplasty included: patient risk factors (age, sex, body mass index, race, and general health status), implant risk factors (fixation type, bearing surface, femoral head size, and component replacement), and surgeon risk factors (volume and experience). A multivariable Cox proportional hazards model was used. Six hundred and twenty-nine revision total hip arthroplasties with sixty-three (10%) re-revisions were evaluated. The mean cohort age (and standard deviation) was 57.0 ± 12.4 years, the mean body mass index (and standard deviation) was 29.5 ± 6.1 kg/m(2), and most of the patients were women (64.5%) and white (81.9%) and had an American Society of Anesthesiologists score of associated with the risk of re-revision. For every ten-year increase in patient age, the hazard ratio for re-revision decreases by a factor of 0.72 (95% confidence interval, 0.58 to 0.90). For every five revision surgical procedures performed by a surgeon, the risk of revision decreases by a factor of 0.93 (95% confidence interval, 0.86 to 0.99). At the time of revision, a new or retained cemented femoral implant or all-cemented hip implant increases the risk of revision by a factor of 3.19 (95% confidence interval, 1.22 to 8.38) relative to a retained or new uncemented hip implant. A ceramic on a

Abuso de drogas e transtornos alimentares entre mulheres: sintomas de um mal-estar de gênero?

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Regina Helena Simões-Barbosa

Full Text Available Resumo: O artigo discute o abuso de drogas e os transtornos alimentares sob as perspectivas críticas de gênero e do cuidado em saúde. Postula-se que o sofrimento subjetivo pode se expressar no corpo por meio das doenças psicossomáticas. Nessa perspectiva, a insaciável fome consumista das drogas ou de bens supérfluos, bem como o adoecimento pela fome voluntária em busca de um ideal de esbeltez, como na anorexia e bulimia, podem ser sintomas que denunciam o sofrimento feminino. Uma revisão nos campos da saúde coletiva e das teorias feministas destaca a magnitude dos fenômenos da medicalização e mercantilização da saúde presentes na psiquiatrização do mal-estar feminino. Na transição de gênero das sociedades capitalistas, as cobranças sociais pelo desempenho dos velhos e novos papéis femininos acentuam sentimentos de inadequação, traduzidos no mal-estar de gênero que circunda o abuso de drogas e os transtornos alimentares, analisados como patologias de protesto. Propõe-se o resgate do ideário do Programa de Assistência Integral à Saúde da Mulher, orientado pela integralidade, para enfrentar tais desafios.

Algoritmo para monitoramento da incidência da malária na Amazônia brasileira, 2003 a 2010

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Rui Moreira Braz

2014-03-01

Full Text Available OBJETIVO: Avaliar um algoritmo para detecção da variação da incidência da malária nos municípios da Amazônia brasileira. MÉTODOS: Avaliou-se um sistema de monitoramento automatizado, baseado em um algoritmo desenvolvido anteriormente pelos autores. O algoritmo utiliza o diagrama de controle por quartis para classificação dos municípios em quatro grupos, conforme a variação da incidência da malária: grupo 1 (redução da incidência-aqueles com incidência abaixo dos valores esperados; grupo 2 (incidência esperada-aqueles com incidência dentro dos valores esperados; grupo 3 (epidemia-aqueles com incidência acima dos valores esperados; grupo 4 (caso esporádico-aqueles com apenas um caso durante o ano. O período de análise foi de 2003 a 2010. Foram estudados todos os municípios existentes nos nove estados que compõem a Amazônia brasileira (805 municípios em 2003 e 807 a partir de 2004. RESULTADOS: Com base nessa metodologia, os municípios da região foram assim classificados: grupo 1, 152 municípios (18,8% da região em 2003 e 109 (13,5% em 2010; grupo 2, 206 (25,6% em 2003 e 331 (41,0% em 2010; grupo 3, 391 (48,6% em 2003 e 308 (38,2% em 2010; e grupo 4, 56 (7,0% em 2003 e 59 (7,3% em 2010. CONCLUSÕES: O algoritmo possibilitou verificar que, na Amazônia brasileira, o número de municípios com epidemias de malária em 2010 diminuiu em relação a 2003, enquanto o número de municípios com incidência esperada aumentou. No mesmo período, houve pouca variação no número de municípios com redução da incidência e daqueles com casos esporádicos.

Mal de Montaña, migraña y depresión: Coexistencia casual o causal? Posible rol de la hipoxia ambiental.

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Alberto Arregui

1995-10-01

Full Text Available Objetivo: Estudiar la posible asociación entre mal de montaña crónico, migraña y depresión. Material y métodos: Estudio epidemiológico realizado en setiembre de 1990en 379 hombres adultos con residencia permanente en la ciudad de Cerro de Pasco (4300 m.s.n.m.; se hicieron 15 preguntas asociadas a depresión y 9 preguntas asociadas al mal de montaña crónico (MMC con las que se calcularon puntajes de depresión y del mal de montaña crónico. Los puntajes por encima de dos desviaciones estándar de la media fueron considerados como altos. Resultados: La frecuencia de migrañas fue de 48.3% entre hombres con puntajes altos de MMC y de 26.5% entre aquellos con puntajes normales (p=0.013. El 16.7% de hombres con puntaje alto de MMC tuvo puntaje alto de depresión mientras que sólo el 6.5% con puntaje normal de MMC tuvo puntaje alto de depresión (p=0.04. El riesgo de tener puntaje alto de depresión o de MMC fue más del doble entre hombres con migrañas comparados con hombres sin migrañas. La posibilidad de tener migraña o puntajes alto de MMC, fue tres veces mayor entre hombres con puntajes alto de depresión comparados con los que tuvieron puntajes de MMC más altos que aquellos sin cefaleas o con otros tipos de cefaleas. Conclusiones: Los datos muestran una coexistencia más que casual entre estas tres entidades clínicas. Se sugiere que un factor de riesgo común a las tres sea la hipoxia crónica que podría producir cambios neuroquímicos en el cerebro que explicaría, en parte, los síntomas de estos tres síndromes. Los datos también sugieren que los síntomas subjetivos que ocurren en el mal de montaña crónico son similares a los que ocurren en la depresión. (Rev Med Hered 1996; 6: 163-167.

[Surgical procedures involved in claims for alleged defects in praxis].

Science.gov (United States)

Arimany-Manso, Josep; Benet-Travé, J; Bruguera-Cortada, M; Torné-Escasany, R; Klamburg-Pujol, J; Gómez-Durán, Esperanza L

2014-03-01

Medical professional liability and adverse events in health care are major concerns worldwide and the analysis of claims for alleged defects in praxis is a potential source of knowledge. High rates of adverse events and complaints have been reported in surgical procedures. This article analyzes the claims registered by the Council of Medical Colleges in Catalonia between 1986 and 2012, and explores surgical procedures claimed (ICD- 9-CM coding), as well as the final outcome of the claim. Among the 5,419 records identified on surgical procedures, the interventions of the musculoskeletal system and skin and integument showed the highest frequencies. Interventions related to "non-curative" medicine should be emphasized because of their higher rates of economical agreement or condemnation outcomes, which were significantly higher for mastopexia. The results underscore the importance of the surgical area in medical professional liability and the high risk of payouts among those procedures belonging to the so-called "non-curative" medicine. Copyright © 2014 Elsevier España, S.L. All rights reserved.

EDUCACIÓN Y SOCIEDAD: APUNTES PARA UNA APROXIMACIÓN A LA PRAXIS EDUCATIVA DESDE EL MARXISMO

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Luis Carlos Morales Zúñiga

2009-01-01

Full Text Available El artículo realiza un análisis sobre el fenómeno educativo desde la perspectiva marxista, con el propósito de observar las principales tesis que se han planteado desde el aparato teórico-metodológico marxista sobre la praxis educativa y sobre el sistema educativo. Por otro lado se analizan elementos como el rol docente, los libros de texto y los programas de estudio, como factores que actúan en el proceso de transposición ideológica en los procesos de enseñanza-aprendizaje.

El método antropológico-trascendental de Karl Rahner como hermenéutica teológica del mundo y de la praxis

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Fernando Berríos

2004-01-01

Full Text Available La conmemoración del 40º aniversario del Concilio Vaticano II (1962-1965 es una ocasión propicia para releer sus enseñanzas e intuiciones fundamentales y evaluar su recepción en el pensamiento y en la vida de la Iglesia. El artículo se propone aportar a esta tarea con una aproximación al tema de la praxis en sintonía con la doctrina de la constitución Gaudium et spes sobre la actividad humana en el mundo (GS 33-39. En ese espíritu, el artículo ofrece una presentación del método antropológico-trascendental del teólogo alemán Karl Rahner (1904-1984 como un camino de lectura teológica del mundo y de la praxis histórica relevante para los cristianos de hoy. Sitúa dicho método en el programa rahneriano de un "recentramiento antropológico" de la teología (1. y explica su enfoque "trascendental" a la luz de su subyacente apertura al mundo moderno (2.; analiza someramente las diversas líneas que constituyen su sustrato filosófico (3. y lo confronta con otro enfoque trascendental relevante como es el del filósofo francés Maurice Blondel (4., para concluir con algunas reflexiones y perspectivasThe commemoration of the 40th anniversary of the Vatican Council II (1962-1965 is a suitable occasion to go over its fundamental teaching and institutions again and assess their acceptance to the thought and life of the Church. This article attempts to make a contribution, presenting new lights on the issue of the praxis along with the doctrine of the Constitution Gaudium et Spes on the human activity in the world (GS 33-39. The article presents Karl Rahner's (1904-1984 anthropologic-transcendental method as a theological reading of the world and the historical praxis significant for modern Christians. The author sets this method within Rhaner's program of an `anthropological re-centering' of theology. Thus he (1 explains his `transcendental' approach in the light of the opening of the new world, (2 analyses the various lines underlying

Revision Total Hip Arthoplasty: Factors Associated with Re-Revision Surgery

OpenAIRE

Khatod, M; Cafri, G; Inacio, MCS; Schepps, AL; Paxton, EW; Bini, SA

2015-01-01

The survivorship of implants after revision total hip arthroplasty and risk factors associated with re-revision are not well defined. We evaluated the re-revision rate with use of the institutional total joint replacement registry. The purpose of this study was to determine patient, implant, and surgeon factors associated with re-revision total hip arthroplasty.A retrospective cohort study was conducted. The total joint replacement registry was used to identify patients who had undergone revi...

Presencia de Anopheles (Nyssorhynchus benarrochi en áreas de selva con transmisión malárica

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Roberto Fernández L

2004-10-01

Full Text Available Objetivos: Demostrar la presencia de An. (Nys. benarrochi en áreas de transmisión malárica, donde es frecuentemente identificado como An. evansae. Materiales y métodos: Se colectaron mosquitos en San José (Pucallpa, Muniches y Andoas (Alto Amazonas, localidades con transmisión de malaria. Con estos mosquitos se efectuaron crías biológicas en laboratorio con la finalidad de obtener material de estudio como son exuvias de larvas, pupas, adultos hembras y machos. Se efectuaron montajes de exuvias de larvas y pupas asociados con sus respectivos adultos, disecciones de las genitalias de machos y biometría de los adultos machos y hembras. Resultados: Además de las verificaciones efectuadas en el campo, basadas en el estudio de inmaduros y adultos, las crías biológicas efectuadas confirmaron la presencia de An. benarrochi en las localidades mencionadas. Asimismo, confirmaron también la existencia de gran variabilidad de los caracteres morfológicos externos, que pueden inducir al error en las identificaciones. Conclusiones: En las áreas maláricas estudiadas, la especie identificada como An. (Nys. evansae corresponde a An. (Nys. benarrochi, demostrado con nuestros estudios. Dada la variabilidad de caracteres que dificultan la identificación de las especies afines, es necesario realizar estudios completos con la finalidad de conocer la fauna local de anofelinos.

Casual Empire: Video Games as Neocolonial Praxis

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Sabine Harrer

2018-01-01

Full Text Available As a media form entwined in the U.S. military-industrial complex, video games continue to celebrate imperialist imagery and Western-centric narratives of the great white explorer (Breger, 2008; Dyer-Witheford & de Peuter, 2009; Geyser & Tshalabala, 2011; Mukherjee, 2016. While much ink has been spilt on the detrimental effects of colonial imagery on those it objectifies and dehumanises, the question is why these games still get made, and what mechanisms are at work in the enjoyment of empire-themed play experiences. To explore this question, this article develops the concept of ‘casual empire’, suggesting that the wish to play games as a casual pastime expedites the incidental circulation of imperialist ideology. Three examples – 'Resident Evil V' (2009, 'The Conquest: Colonization' (2015 and 'Playing History: Slave Trade' (2013 – are used to demonstrate the production and consumption of casual empire across multiple platforms, genres and player bases. Following a brief contextualisation of postcolonial (game studies, this article addresses casual design, by which I understand game designers’ casual reproduction of inferential racism (Hall, 1995 for the sake of entertainment. I then look at casual play, and players’ attitudes to games as rational commodities continuing a history of commodity racism (McClintock, 1995. Finally, the article investigates the casual involvement of formalist game studies in the construction of imperial values. These three dimensions of the casual – design, play and academia – make up the three pillars of the casual empire that must be challenged to undermine video games’ neocolonialist praxis.

Sobre el mal radical. Ensayo de la heterodoxia kantiana

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Gómez Caffarena, José

2004-06-01

Full Text Available The kantian theory of a «radical evil inhabiting human nature» contrasts with a general anthropological optimistic tenor perceptible in kantian philosophy. It meant a significant turning point in the often too superficial optimistic trends of the Enlightenment. Hut its literal sense (appealing to an act of pre-individual freedom has an obvious difficulty. The present paper proposes an heterodox interpretation, which would avoid the difficulty, although so losing part of the tempting enigmatic reach of the kantian proposal.

La teoría del «mal radical en la naturaleza humana», expuesta por Kant en La religión dentro de los límites de la mera razón, hace contraste con el optimismo antropológico que empapa el Criticismo. Constituyó, sin duda, una importante denuncia frente a la banalidad de muchos optimismos ilustrados. Pero su letra (acto de libertad pre-individual tiene una obvia dificultad. El artículo propone una reinterpretación que la evitaría, aunque desdramatizando un tanto el tentador alcance enigmático de la propuesta kantiana.

Revised

DEFF Research Database (Denmark)

Johannsen, Vivian Kvist; Nord-Larsen, Thomas; Riis-Nielsen, Torben

This report is a revised analysis of the Danish data on CO2 emissions from forest, afforestation and deforestation for the period 1990 - 2008 and a prognosis for the period until 2020. Revision have included measurements from 2009 in the estimations. The report is funded by the Ministry of Climate...

Gravidade do transtorno fonológico, consciência fonológica e praxia articulatória em pré-escolares Severity of phonological disorder, phonological awareness and articulatory praxis in preschoolers

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Thaís Nobre Uchôa Souza

2011-06-01

Full Text Available OBJETIVO: Caracterizar o transtorno fonológico quanto à gravidade, consciência fonológica e praxia articulatória e investigar a existência de correlações entre essas variáveis, em um grupo de pré-escolares. MÉTODOS: Participaram 56 pré-escolares entre 4 anos e 6 anos e 11 meses, meninos e meninas, separados em Grupo Pesquisa (GP e Grupo de Comparação (GC, respectivamente à presença ou ausência de alterações de fala. Foram aplicados: Teste de Linguagem Infantil ABFW: Fonologia; Consciência Fonológica: Instrumento de Avaliação Sequencial - CONFIAS; e o Protocolo de Avaliação das Praxias Articulatórias e Buco-faciais. Realizou-se o cálculo da Porcentagem de Consoantes Corretas - PCC para classificar a gravidade do transtorno fonológico. Os dados receberam análise estatística. RESULTADOS: Os pré-escolares com transtorno apresentaram desempenho inferior em tarefas de consciência fonológica e praxia articulatória quando comparados aos do GC. A gravidade correlacionou-se com consciência fonológica e praxia articulatória e esta com consciência fonológica nesses pré-escolares. Ambos os grupos mostraram correlação entre consciência fonológica total, consciência fonológica de sílaba e de fonema. CONCLUSÃO: O GP caracterizou-se pelo pior desempenho em consciência fonológica e praxia articulatória e pela presença de correlação entre a gravidade do transtorno, a consciência fonológica e a praxia articulatória.PURPOSE: To characterize the phonological disorder regarding severity, phonological awareness and articulatory praxis, and to investigate the existence of correlations among these variables in a group of preschoolers. METHODS: Participants were 56 preschoolers of both genders with ages between 4 years and 6 years and 11 months, split into Research Group (RG and Comparison Group (CG, according to the presence or absence of speech alterations. The following tests were carried out: Child Language

Development of hypo-allergenic apples: silencing of the major allergen Mal d 1 gene in "Elstar" apple and the effect of grafting

DEFF Research Database (Denmark)

Krath, Britta; Eriksen, Folmer Damsted; Pedersen, Bjarne H.

2009-01-01

Many people who are allergic to birch pollen are also allergic to apple fruit, due to cross-allergenicity. Since apples are the most extensively consumed fruit in Europe, it is highly relevant to develop a hypo-allergenic apple. Apples with significantly reduced levels of the allergen, Mal d 1, may...

DIREITO DE EXCEÇÃO: OS RISCOS DE UM MAL NECESSÁRIO

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Mariana Belchior Ribeiro Freire

2010-08-01

Full Text Available O presente trabalho tem como escopo analisar o estado de exceção no seu liame entre a manutenção do status quo ante e o salto para a revolução. Sob a óptica dos pensamentos de renomados filósofos (Jean Bodin, Thomas Hobbes, Rosseau, Hans Kelsen e Carl Schmitt, procuramos analisar os benefícios e os riscos da instituição do estado de exceção, tendo em vista que se pode considerar este um mal necessário. O estado de exceção é um avanço nas democracias contemporâneas, como observaremos a sua previsão importa uma segurança à sociedade de que é possível mudar preservando alguns direitos constitucionais.

Decision-Making and Sources of Evidence in Occupational Therapy and Other Health Professions. Evidence-Informed Practice / Entscheidungsfindung und Evidenzquellen in der Ergotherapie und weiteren Gesundheitsberufen. Evidenzinformierte Praxis

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Tomlin George S.

2014-12-01

Full Text Available Von den Gesundheitsberufen wird einerseits verlangt, dass jeder einzelne Praktiker wissenschaftsbasiert arbeitet, d.h. publizierte Evidenz in der Praxis anwendet (Evidence Based Practice, EBP. Andererseits müssen sie als Profession valide Evidenz der Ergebnisse ihres professionellen Handelns produzieren. Diese zwei Dimensionen von EBP werden in der Diskussion oft nicht auseinander gehalten, was zu Verwirrung führt. Dieser theoretische Beitrag differenziert diese beiden Prozesse als “Evidence- Supported Practice” und “Evidence-Informed Practice” und zeigt, wie sie wieder zusammengeführt werden können. Zur Bewertung der externen und internen Validität von externer Evidenz wird die Forschungspyramide verwendet. In der Alltagspraxis müssen externe und interne Evidenzarten verwendet werden. Um den Begriff der internen Evidenz zu erklären, werden Beispiele aus der Ergotherapie und aus der Literatur anderer Gesundheitsberufe herangezogen. Empfehlungen für eine umfassende Strategie Evidenz-Basierter Praxis, adressiert an Praktiker, Forscher, und Lehrer werden formuliert.

Theorie & Praxis des Lehrer Angst und Stress Test: (Lehramts-)StudentInnen & Lehrkräfte im Vergleich

OpenAIRE

Preidel, Julia; Weikamp, Julia; Werhand, Manuela

2009-01-01

Der Lehrer Angst und Stress Test (LAST) ist ein Test, der für die Messung von Lehrerangst angedacht ist. Lehrerangst umfasst all jene Ängste von Lehrern, die sie bei der Ausübung ihres Berufs erfahren. Der LAST fragt hierzu nach Reaktionsweisen auf Belastungssituationen, der Stärke zweier Angstkomponenten, nach Faktoren, die zur Angstverstärkung führen und nach Bewältigungsstrategien. Diese Arbeit soll die Testgüte des LAST ein weiteres Mal überprüfen. Diesbezüglich wurde getestet, inwiefe...

Transmisión del Mal de Río Cuarto virus por ninfas de primer y tercer estadio de Delphacodes kuscheli Transmission of Mal de Río Cuarto virus by first and third-instar nymphs of Delphacodes kuscheli

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Joel Arneodo

2005-02-01

Full Text Available Se comparó la capacidad de ninfas de primer y tercer estadío de Delphacodes kuscheli Fennah (Hemiptera: Delphacidae para adquirir y posteriormente transmitir el Mal de Río Cuarto virus (MRCV, bajo condiciones controladas. Ninfas I y III avirulíferas se alimentaron separadamente de plantas de trigo infectadas durante 48 horas, para luego ser colocadas en subgrupos de tres individuos sobre plantas de trigo sanas. Se realizaron transmisiones seriales utilizando períodos de inoculación de 24 horas. Ambos estadií os lograron adquirir y transmitir el MRCV, pero se evidenció una mayor cantidad de subgrupos infectivos cuando la adquisición se efectuó como ninfas I, así como una disminución significativa en la duración del período de latencia del virus respecto de los insectos que adquirieron el MRCV durante el tercer estadio ninfal.The ability of first and third-instar Delphacodes kuscheli Fennah (Hemiptera: Delphacidae nymphs to acquire and transmit Mal de Río Cuarto virus (MRCV, under controlled conditions, was investigated. First and third-instar nymphs were allowed acquisition feeding separately on infected wheat plants for 48 hours. The insects were then placed in groups of three for serial transmissions to healthy wheat plants, using inoculation periods of 24 hours. Both instars of D. kuscheli were demonstrated to acquire and subsequently transmit the virus. Nevertheless, transmission trials showed highest transmission efficiency and shortest latent period when MRCV was acquired by first-instar nymphs.

Hypothesis: The Vestibular and Cerebellar Basis of the Mal de Debarquement Syndrome

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Bernard Cohen

2018-02-01

Full Text Available The Mal de Debarquement syndrome (MdDS generally follows sea voyages, but it can occur after turbulent flights or spontaneously. The primary features are objective or perceived continuous rocking, swaying, and/or bobbing at 0.2 Hz after sea voyages or 0.3 Hz after flights. The oscillations can continue for months or years and are immensely disturbing. Associated symptoms appear to be secondary to the incessant sensation of movement. We previously suggested that the illness can be attributed to maladaptation of the velocity storage integrator in the vestibular system, but the actual neural mechanisms driving the MdDS are unknown. Here, based on experiments in subhuman primates, we propose a series of postulates through which the MdDS is generated: (1 The MdDS is produced in the velocity storage integrator by activation of vestibular-only (VO neurons on either side of the brainstem that are oscillating back and forth at 0.2 or 0.3 Hz. (2 The groups of VO neurons are driven by signals that originate in Purkinje cells in the cerebellar nodulus. (3 Prolonged exposure to roll, either on the sea or in the air, conditions the roll-related neurons in the nodulus. (4 The prolonged exposure causes a shift of the pitch orientation vector from its original position aligned with gravity to a position tilted in roll. (5 Successful treatment involves exposure to a full-field optokinetic stimulus rotating around the spatial vertical countering the direction of the vestibular imbalance. This is done while rolling the head at the frequency of the perceived rocking, swaying, or bobbing. We also note experiments that could be used to verify these postulates, as well as considering potential flaws in the logic. Important unanswered questions: (1 Why does the MdDS predominantly affect women? (2 What aspect of roll causes the prolongation of the tilted orientation vector, and why is it so prolonged in some individuals? (3 What produces the increase in symptoms of

Faktoring – jedna z hlavních forem financování malých a středních podniků

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Müllerová Libuše

2009-12-01

Full Text Available Faktoring představuje službu, kterou poskytují specializované faktoringové společnosti svým klientům v souvislosti s postoupením nebo se správou pohledávek. Ve své podstatě se jedná o určitý způsob úvěrování, využívaný zejména malými a středními podniky. V praxi existuje několik forem faktoringu v závislosti na tom, do jaké míry přechází na faktora vlastnictví pohledávek a rizika jejich nesplacení. Podle toho se pak faktoringové transakce promítají do účetnictví faktora i klienta. Vzhledem k tomu, že tato služba ani její formy není upravená žádným právním předpisem, postupují faktoringové společnosti často tak, že podmínky ve smlouvách – z důvodu daňových – často zakrývají svojí formou skutečný stav. Uvedený příspěvek základní formy faktoringu vymezuje, popisuje jejich správné účtování včetně daňových dopadů. Factoring is a service, which is offered by specialized factoring agencies to their clients in case of transfer (sale or governance of receivables. In fact, it represents a specific mode of crediting which is mostly preferred by small and medium enterprises. In practices of factoring several forms are differentiated depending on scale of property and risk transfer to the factor. According to these circumstances the factoring transactions are recognized by the factor and the client. The factoring services are not so far regulated by any legal provision. For this reason factoring agencies are proceeding in such a way, that contract conditions – because of tax considerations – hide by their form the substance. The paper describes the factoring forms and interprets their correct recognition on accounting, including tax consequences.

SmartMal: A Service-Oriented Behavioral Malware Detection Framework for Mobile Devices

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Chao Wang

2014-01-01

Full Text Available This paper presents SmartMal—a novel service-oriented behavioral malware detection framework for vehicular and mobile devices. The highlight of SmartMal is to introduce service-oriented architecture (SOA concepts and behavior analysis into the malware detection paradigms. The proposed framework relies on client-server architecture, the client continuously extracts various features and transfers them to the server, and the server’s main task is to detect anomalies using state-of-art detection algorithms. Multiple distributed servers simultaneously analyze the feature vector using various detectors and information fusion is used to concatenate the results of detectors. We also propose a cycle-based statistical approach for mobile device anomaly detection. We accomplish this by analyzing the users’ regular usage patterns. Empirical results suggest that the proposed framework and novel anomaly detection algorithm are highly effective in detecting malware on Android devices.

Epilepsia"Petit Mal" aspectos clínicos, eletrencefalográficos e evolutivos

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Paulo Pinto Pupo

1961-01-01

Full Text Available In the past few years somewhat new yet often differing points of view have been affirmed refering to Petit Mal epilepsy, with regard to its clinical, eletrencephalographic and evolutive aspects. The classical concept of PM epilepsy as established by Lennox and Gibbs, with its well defined clinical and EEGraphic characteristics is continually being modified with new research work on clinical and EEGraphic aspects. Numerous clinical cases have been published whose evolution clashes with that classically described and likewise numerous are those cases where the EEG shows signs of focal electric activity besides spike and wave dis-rythmia. Cases have been known where surgical exerese on the focus causes temporary desappearance of the spike and wave disrythmia. The present concept now holding sway is that PM epilepsy is a kind of reaction of infantile encephalon to diverse harmful causes. From this it will be seen we are very far from the concept that PM epilepsy is a pure form of idiopathic epilepsy. For these reasons we decided to re-examine those cases observed between 1950 and 1960. With this in mind we chose 141 PM epilepsy cases, from among over 23000 epileptics, all examined under a standard criterion by a small group of senior assistants. All cases suspected of Psm epilepsy were excluded. The analysis of this group of patients was compared to that of another group with GM as well as PM seizures (104 patients; in 52 of these cases, studies were made concerning the evolutive, clinical and EEGra-phic aspects. METHOD: Clinical criterion was used for selection of the cases. The results of the analysis from the clinical and EEGraphic point of view were exhibited in demonstrative graphs. From the clinical point of view we strove to find out positive hereditary elements, organic cerebral injury factor (intellectual deficit, mood and behaviour disturbances, neurologic or somatic signs, as well as other development anomalies, the presence of febrile

Nanotecnologia farmacêutica aplicada ao tratamento da malária Application of pharmaceutical nanotechnology to the treatment of malaria

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Lúcio Figueira Pimentel

2007-12-01

Full Text Available Apesar do desenvolvimento tecnológico e científico, a malária permanece como um dos maiores problemas de saúde a serem combatidos. As estratégias modernas para o controle da doença prevêem ações conjuntas, como o combate do inseto vetor, diagnóstico rápido e preciso, garantia de terapêutica adequada, redução dos casos de resistência, além do desenvolvimento de novos agentes terapêuticos e vacina e através da otimização da ação de fármacos utilizados na atualidade. Os sistemas de liberação controlada de fármacos vêm recebendo atenção especial nesta área de pesquisa, com o desenvolvimento de estratégias para a veiculação de agentes bioativos e vacinas na forma de nanodispositivos tais como lipossomas, nanopartículas e micropartículas. Diversos nanossistemas já demonstraram eficácia na otimização de vacinas e quimioterápicos destinados ao controle da malária. Este artigo de revisão tem por objetivo avaliar o estado da arte na terapêutica da malária e demonstrar o potencial da nanotecnologia farmacêutica como ferramenta destinada ao combate da doença.In spite of living in a scientific and technological era, malaria continues to be one of the worldwide greatest health challenges. The state-of-the-art policy to keep malaria under control is expected to comprise joint-strategies, such as the vector control, fast diagnosis, therapeutic guarantee, resistance cutback, drug optimization and development of new therapeutic agents and vaccines. Nano and microcarrier systems have been receiving a special attention, including the development of strategies for carrying bioactive agents, vaccines through nanodevices, such as liposomes and nanoparticles, and microdevices, such as microparticles and microemulsions. Numerous nanosystems have already substantiated their effectiveness to optimize vaccines, insecticides, and chemotherapeutic agents applied to the control of malaria. This review is intended to explain the

New environmental criminal law, effects and enforcement in practice; Neues Umweltstrafrecht und betriebliche Praxis

Energy Technology Data Exchange (ETDEWEB)

Knopp, L.

1994-11-20

Since the November 1, 1994 a more comprehensive and clearly tighter environmental criminal law is in force. With the amendment of the law defects and gaps of the previous environmental criminal administrative offence law are to be closed in order to imporve also the efficient flight against behaviour or measures which are detrimental or harmful to the environment. The author explains the most important new regulations and shows the effects of the enforcement of the law in practice. (orig.) [Deutsch] Seit 1.11.1994 gilt ein erweitertes und deutlich verschaerftes Umweltstrafrecht. Mit der Gesetzesnovelle sollen Luecken und Maengel des bislang geltenden Umweltstraf- und Ordnungswidrigkeitenrechts beseitigt werden, um damit zugleich eine wirksamere Bekaempfung umweltschaedlicher und umweltgefaehrlicher Handlungen zu verbessern. Der Autor gibt einen Ueberblick ueber die wichtigsten Neuregelungen und zeigt die Auswirkungen fuer die betriebliche Praxis auf. (orig.)

Retardo no crescimento intrauterino, baixo peso ao nascer e prematuridade em recém-nascidos de grávidas com malária, na Colômbia Intrauterine growth retardation, low birth weight and prematurity in neonates of pregnant women with malaria in Colombia

OpenAIRE

Alberto Tobón-Castaño; Martha Arismendi Solano; Luis Gonzalo Álvarez Sánchez; Silvia Blair Trujillo

2011-01-01

INTRODUÇÃO: É frequente a associação da malária com complicações como prematuridade, retardo no crescimento intrauterino, baixo peso ao nascer e mortalidade infantil, efeitos pouco estudados em áreas hipoendêmicas para malaria. O objetivo deste estudo foi analisar a relação da malária gestacional com estes efeitos em recém-nascidosnuma região endêmica para malária na Colômbia, entre 1993 e 2007. MÉTODOS: Foram estudadas as características em 1.716 recém-nascidos num estudo de coorte. Fez-se s...

Debata o památkové péči v 60. letech 20. století. Ivo Loos, Jindřich Malátek a Transgas

Czech Academy of Sciences Publication Activity Database

Švácha, Rostislav

2017-01-01

Roč. 77, č. 4 (2017), s. 361-372 ISSN 1210-5538 Institutional support: RVO:68378033 Keywords : Jindřich Malátek * Ivo Loos * postwar architecture * theory of architecture and heritage care * Transgas Subject RIV: AL - Art, Architecture, Cultural Heritage

Imaginative ethics--bringing ethical praxis into sharper relief.

Science.gov (United States)

Hansson, Mats G

2002-01-01

The empirical basis for this article is three years of experience with ethical rounds at Uppsala University Hospital. Three standard approaches of ethical reasoning are examined as potential explanations of what actually occurs during the ethical rounds. For reasons given, these are not found to be satisfying explanations. An approach called "imaginative ethics", is suggested as a more satisfactory account of this kind of ethical reasoning. The participants in the ethical rounds seem to draw on a kind of moral competence based on personal life experience and professional competence and experience. By listening to other perspectives and other experiences related to one particular patient story, the participants imagine alternative horizons of moral experience and explore a multitude of values related to clinical practice that might be at stake. In his systematic treatment of aesthetics in the Critique of Judgement, Kant made use of an operation of thought that, if applied to ethics, will enable us to be more sensitive to the particulars of each moral situation. Based on this reading of Kant, an account of imaginative ethics is developed in order to bring the ethical praxis of doctors and nurses into sharper relief. The Hebraic and the Hellenic traditions of imagination are used in order to illuminate some of the experiences of ethical rounds. In conclusion, it is argued that imaginative ethics and principle-based ethics should be seen as complementary in order to endow a moral discourse with ethical authority. Kantian ethics will do the job if it is remembered that Kant suggested only a modest, negative role of principle-based deliberation.

Uruguay mining inventory results of the Mal Abrigo aerial photography chemical prospect ion

International Nuclear Information System (INIS)

Zeegers, H.; Artignan, D.; Vairon, P.

1982-01-01

This report presents the results of the chemical prospecting strategic multielemental carried out, of the mining Inventory framework from the Uruguay aerial photography Mal Abrigo (sector M 25, area 82). The covered surface is of 660 km with a total of 753 samples, corresponding to an approximate sampling density of 1.14 samples for krri2; in parallel pH measures and radioactivity were made. The samples were analyzed in the laboratories of the BRGM (Orleans), for 22 elements for Spectrometry of Emission Captures. The geochemical answer in connection with the litology was good. Sixteen anomalies, little contrasted has been retained in what concerns to the elements Pb, Zn, Cu, Ace, Ag, and W; eight of those which are constituted for regrouping points. The main purpose has been to search ultramafic rocs in Cerro Chato -Durazno province.

Luminescent properties of MAl(SO4)2 Br:Eu(3+) (M = Sr or Mg) red phosphors for near-UV light-emitting diodes.

Science.gov (United States)

Deshmukh, Priti B; Puppalwar, S P; Dhoble, N S; Dhoble, S J

2015-02-01

Eu(3+) -activated MAl(SO4 )2 Br phosphors (where M = Mg or Sr) are successfully prepared using a wet chemical reaction technique. The samples are characterized by X-ray diffraction (XRD) and photoluminescence (PL) spectroscopies. The XRD pattern revealed that both the samples are microcrystalline in nature. PL of Eu(3+) -doped SrAl(SO4 )2 Br and MgAl(SO4 )2 Br phosphors exhibited characteristic red emission coming from the (5) D0  → (7) F2 (616 nm) electron transition, when excited by 396 nm wavelength of light. The maximum intensity of luminescence was observed at a concentration of 1 mol% Eu(3+) . The intensity of the electric dipole transition at 616 nm is greater than that of the magnetic dipole transition at 594 nm. The results showed that MAl(SO4 )2 Br:Eu(3+) , (M = Mg, Sr) phosphors have potential application in near-UV light-emitting diodes as efficient red-emitting phosphor. Copyright © 2014 John Wiley & Sons, Ltd.

Surto de malária induzida entre usuários de drogas injetáveis Outbreak of malaria among injectable-drug users

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Luiz Carlos Barradas Barata

1993-02-01

Full Text Available Em julho de 1990, foi registrado na cidade de Bauru, Estado de São Paulo, Brasil, um surto de malária envolvendo usuários de cocaína injetável. Uma ampla investigação epidemiológica, conduzida de 19 de julho a 13 de setembro, revelou que pelo menos 119 pessoas estavam envolvidas no surto, uma vez que haviam compartilhado seringas e agulhas com um ou mais casos confirmados nos 3 meses anteriores à ocorrência. Cento e duas dessas pessoas foram localizadas e entrevistadas, e destas, 99 foram submetidas a exame de gota espessa e 91 a exames sorológicos para malária. Foram confirmados por exame hemoscópico 21 casos de malária por P. vivax, e 3 outros tiveram exame sorológico positivo para P. vivax. O controle da transmissão foi obtido fornecendo-se cloroquina aos envolvidos no surto, numa dose inicial de 10 comprimidos, seguida de doses supressivas semanais de 2 comprimidos até que fosse identificado o último comunicante. Amostras de soro coletadas na ocasião revelaram, ao lado da malária, uma alta prevalência de infecções pelo HIV (58% e pelo vírus da hepatite B (40%. Foram discutidas as dificuldades para o controle do surto e a possibilidade da malária vir a se tornar uma doença endêmica entre usuários de drogas injetáveis, no Estado de São Paulo.Five cases of malaria were detected among cocaine users by the local health service in Bauru, a city with a population of 260,000, located 324 km from S. Paulo, Brazil, during the first three weeks of July 1990. Autochthonous malaria had not occurred in Bauru since 1978, and all the five cases denied having recently traveled to endemic areas. An extensive epidemiologic survey conducted from July 19 to September 13 revealed that the 5 cases were in fact part of a malaria outbreak among endovenous drug users. Moreover, at least 114 other people, who had in the last three months shared syringes and needles with one or more proved cases, were also involved in the outbreak. One

Teste de hemaglutinação na sorologia da malária humana empregando hemácias parasitadas pelo Plasmodium berghei

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Maria Carmen Arroyo Sanchez-Ruiz

1985-06-01

Full Text Available Foi padronizado um teste de hemaglutinação para a sorologia da malária humana, com reagente constituído de suspensão de hemácias de camundongos infectadas pelo Plasmodium berghei e preservadas por fixação aldeídica. Em pacientes com parasitemia por P. falciparum ou P. vivax obteve-se uma sensibilidade de 98,9% nos 88 casos estudados, o teste apresentando títulos entre 40 e 640. Para o grupo de 476 soros de indivíduos não-maláricos, obteve-se uma especificidade de 96,0%. O teste apresentou elevada reprodutibilidade, mesmo para diferentes lotes de antígenos. Nos 200 soros, obtidos ao acaso, de indivíduos de área endêmica, o teste apresentou positividade de 48,5%, contra 88,0% do teste de imunofluorescência-IgG. A baixa positividade pode ser devida a que o teste de hemaglutinação detecta anticorpos IgM. Após tratamento com 2-mercaptoetanol, todos os soros de pacientes com parasitemia tornaram-se não reagentes. Em relação ao teste de imunofluorescência-IgG, o teste de hemaglutinação apresentou índice de co-positívidade de 0,989 para os soros de maláricos com parasitemia. Para os soros de não-maláricos o teste de hemaglutinação apresentou índice de co-negatividade de 0,969. Por outro lado, no grupo de soros de área endêmica, o índice de co-positividade foi de 0,528 e o de co-negatividade, de 0,833.A hemagglutination test is described for human malaria serodiagnosis with aldehyde-fixed Plasmodium berghei infected mouse erythrocytes. In patients with a P. falciparum or P. vivax patent parasitemia positive results were seen in 98.9% ofthe 88 cases tested. Titres rangedfrom 40 to 640. A 96.0% specificity wasfoundfor 476 non-malarialpatients. A close reproducibility was observed forthe test, even for dijferent reagent batches. The test was positive in 48.5% of 200 residents in malaria endemic areas, taken at random. These subjects showed 88.0% positivity of the IgG-immunofluorescence test. This lower positivity for

The method of producing climate change datasets impacts the resulting policy guidance and chance of mal-adaptation

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Marie Ekström

2016-12-01

Full Text Available Impact, adaptation and vulnerability (IAV research underpin strategies for adaptation to climate change and help to conceptualise what life may look like in decades to come. Research draws on information from global climate models (GCMs though typically post-processed into a secondary product with finer resolution through methods of downscaling. Through worked examples set in an Australian context we assess the influence of GCM sub-setting, geographic area sub-setting and downscaling method on the regional change signal. Examples demonstrate that choices impact on the final results differently depending on factors such as application needs, range of uncertainty of the projected variable, amplitude of natural variability, and size of study region. For heat extremes, the choice of emissions scenario is of prime importance, but for a given scenario the method of preparing data can affect the magnitude of the projection by a factor of two or more, strongly affecting the indicated adaptation decision. For catchment level runoff projections, the choice of emission scenario is less dominant. Rather the method of selecting and producing application-ready datasets is crucial as demonstrated by results with opposing sign of change, raising the real possibility of mal-adaptive decisions. This work illustrates the potential pitfalls of GCM sub-sampling or the use of a single downscaled product when conducting IAV research. Using the broad range of change from all available model sources, whilst making the application more complex, avoids the larger problem of over-confidence in climate projections and lessens the chance of mal-adaptation.

 Phronesis and authenticity as keywords for philosophical praxis in teacher training

DEFF Research Database (Denmark)

Hansen, Finn Thorbjørn

2007-01-01

This essay describes the growing interest in and use of concepts such as phronesis and authenticity  in educational research and practice. While phronesis seems to be connected to the ethical dimension  of education and educational guidance, the concept of authenticity seems to be connected to th....... The essay suggests that this Being-dimension can be approached through the  emergence of Communities of Wonder between the teacher and teacher student in the classroom or  guidance session.   Udgivelsesdato: December......This essay describes the growing interest in and use of concepts such as phronesis and authenticity  in educational research and practice. While phronesis seems to be connected to the ethical dimension  of education and educational guidance, the concept of authenticity seems to be connected to the...... of respectively sensing and understanding the Being-dimension. This existence philosophical  approach opens up for a new kind of praxis of Philo-Sophia, which could be realized in teacher  training, when the focus is on how to become more mindful and aware of the Bildung-process in  education and guidance...

Homebirth as systems-challenging praxis: knowledge, power, and intimacy in the birthplace.

Science.gov (United States)

Cheyney, Melissa J

2008-02-01

In this article, I examine the processes and motivations involved when women in the United States choose to circumvent the dominant obstetric care paradigm by delivering at home with a group of care providers called direct-entry midwives. Using grounded theory, participant observation, and open-ended, semistructured interviewing, I collected and analyzed homebirth narratives from a theoretical sample of women (n = 50) in two research locales. Findings interpreted from the perspective of critical medical anthropology suggest that women who choose to birth at home negotiate fears associated with the "just in case something bad happens" argument that forms the foundation for hospital birth rationales through complex individual and social processes. These involve challenging established forms of authoritative knowledge, valuing alternative and more embodied or intuitive ways of knowing, and knowledge sharing through the informed consent process. Adherence to subjugated discourses combined with lived experiences of personal power and the cultivation of intimacy in the birthplace fuel homebirth not only as a minority social movement, but also as a form of systems-challenging praxis.

Malária pulmonar: aspectos na tomografia computadorizada de alta resolução - relato de caso

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Rodrigues Rosana

2004-01-01

Full Text Available Neste trabalho é relatado o caso de paciente do sexo masculino, de 38 anos de idade, que desenvolveu quadro de malária com comprometimento pulmonar. A tomografia computadorizada de alta resolução evidenciou espessamento de septos interlobulares e de bainhas peribroncovasculares, com áreas esparsas de atenuação em vidro fosco e de consolidações, além de derrame pleural bilateral, aspectos compatíveis com edema pulmonar. O paciente recebeu tratamento específico, evoluindo bem e tendo alta 11 dias após a internação.

Revising and editing for translators

CERN Document Server

Mossop, Brian

2014-01-01

Revising and Editing for Translators provides guidance and learning materials for translation students learning to edit texts written by others, and professional translators wishing to improve their self-revision ability or learning to revise the work of others. Editing is understood as making corrections and improvements to texts, with particular attention to tailoring them to the given readership. Revising is this same task applied to draft translations. The linguistic work of editors and revisers is related to the professional situations in which they work. Mossop offers in-depth coverage of a wide range of topics, including copyediting, style editing, structural editing, checking for consistency, revising procedures and principles, and translation quality assessment. This third edition provides extended coverage of computer aids for revisers, and of the different degrees of revision suited to different texts. The inclusion of suggested activities and exercises, numerous real-world examples, a proposed gra...

Sobre los saberes culturales y el fenómeno "sentirse bien-sentirse mal" On cultural knowledge and the phenomenon "feel good-fell bad"

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Virtudes Rodero Sánchez

2010-09-01

Full Text Available El objetivo del presente estudio es identificar los saberes culturales inmersos en el fenómeno "sentirse-bien, sentirse mal", en diferentes situaciones de cuidado. Se elaboró un estudio cualitativo con un enfoque fenomenológico interpretativo, mediante el análisis de 18 narrativas a partir de entrevistas en profundidad realizadas por alumnas del Máster en Ciencias de la Enfermería en diferentes contextos de cuidados. Las categorías identificadas fueron: (1 Cronicidad y concepto de sentirse bien-sentirse mal. En la cronicidad este concepto está íntimamente relacionado con la recuperación de las actividades de la vida diaria y es componente importante en la percepción individual del concepto "calidad de vida". (2 Momentos agudos de enfermedad y concepto de sentirse bien-sentirse mal. En el análisis de los relatos del paciente aparecieron aspectos esenciales del fenómeno "sentirse bien-sentirse mal" para aumentar la comprensión de aspectos universales de algunos de sus componentes. Destacar que el fenómeno está íntimamente relacionado con la recuperación de las actividades de la vida diaria, y es un mediador importante en la percepción individual del concepto "calidad de vida". El interés de cara al cuidado es distinguir sus componentes universales, contextualizarlos en la práctica, dentro de las singularidades que presenta cada persona, de modo que nos permita su potenciación. El resultado es un cambio en la experiencia sentida.The object of the present study is to identify cultural knowledges immersed in the feeling-well, feeling-bad phenomenon in different care settings. A qualitative study was undertaken using a phenomenological interpretation approach through a meta-analysis of 18 narratives of profound interviews undertaken by Nursing Science Master Degree Students in different care situations. The categories established were: (1 Chronicity and the concept of feeling well-feeling bad. In this category, this concept is

AKSESIBILITAS HOTEL HORISON BEKASI DENGAN MAL METROPOLITAN

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Nadia Nursintia

2016-03-01

Full Text Available Abstract - Development of accommodation services is growing very fast, the construction of hotels ranging from low to star property confirms that the business is very profitable and promising. Growing hotel development as the presence and development of tourism in a region. Concept of mix used and are now growing in demand by developers. In addition to shorten the land, its facilities are increasingly in demand, because the concept of developing the land into two business buildings comprising the hotel and mall, can provide ease of access for service users to carry out all the activities that support their activities. Accessibility is a very important thing to be considered for the service users to choose the hotel accommodation that will be flown them. Distance, transportation, facilities, road conditions, and ease of location had been the benchmark and consideration to get a suitable hotel for their activities.   Keyword : Accessibility, Hotel   Abstrak - Perkembangan jasa akomodasi saat ini berkembang sangat cepat, dibangunnya hotel mulai dari hotel rendah hingga bintang menegaskan bahwa bisnis properti ini sangat menguntungkan dan menjanjikan. Pembangunan hotel berkembang seiring hadirnya dan berkembangnya pariwisata di suatu daerah. Konsep mix used pun kini semakin berkembang dan diminati oleh para pengembang. Selain karena mempersingkat lahan, fasilitas nya pun semakin diminati, karena konsep mengembangkan satu lahan menjadi dua bangunan usaha yang terdiri dari hotel dan mal, dapat memberikan kemudahan akses untuk para pengguna jasa untuk melakukan segala aktifitas yang mendukung kegiatannya. Aksesbilitas merupakan hal yang sangat penting yang menjadi pertimbangan bagi para pengguna jasa akomodasi untuk memilih hotel yang akan mereka singgahi. Jarak, transportasi, fasilitas, kondisi jalan, dan kemudahan lokasi lah yang menjadi tolak ukur dan pertimbangan untuk mendapatkan hotel yang cocok bagi kegiatan mereka.   Kata Kunci

Loosening After Acetabular Revision

DEFF Research Database (Denmark)

Beckmann, Nicholas A.; Weiss, Stefan; Klotz, Matthias C.M.

2014-01-01

The best method of revision acetabular arthroplasty remains unclear. Consequently, we reviewed the literature on the treatment of revision acetabular arthroplasty using revision rings (1541 cases; mean follow-up (FU) 5.7 years) and Trabecular Metal, or TM, implants (1959 cases; mean FU 3.7 years...

Prostorové rozhraní informačního systému malé obce řešené v Open Source Software

Directory of Open Access Journals (Sweden)

Karel Jedlička

2006-12-01

Full Text Available Příspěvek si klade za cíl představit možnosti open source software pro implementaci prostorového rozhraní informačního systému malé obce.Zabývá se návrhem projektu po jednotlivých částech: identifikace požadavků zastupitelského úřadu (uživatele systému, popis obecné architektury systému a volba vhodných (nekomerčních technologií pro jeho implementaci. Součástí projektu je i popis vyvinuté technologie pro import nejdůležitějších datových vrstev (informací o vlastnictví do systému.Článek je doplněn výčtem využitelných datových zdrojů pro informační systém malé obce v České republice.

Viveret Patrick, 2005, Pourquoi ça ne va pas plus mal?, Fayard, 264 p.

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Fabien Thurette

2008-05-01

Full Text Available Patrick Viveret est philosophe de formation et Conseiller-maître à la Cour des comptes. Il a, en outre, été chargé d’une mission, confiée par l'éphémère Secrétaire d'État à l'économie solidaire Guy Hascoët, puis prolongée par le Président Chirac sur une « autre approche de la richesse », dont le rapport final a été publié sous le titre Reconsidérer la richesse (2004.Dans son essai Pourquoi ça ne va pas plus mal ? publié en 2005, Patrick Viveret nous livre une analyse philosophique sur le « m...

Co-expression of the Thermotoga neapolitana aglB gene with an upstream 3'-coding fragment of the malG gene improves enzymatic characteristics of recombinant AglB cyclomaltodextrinase.

Science.gov (United States)

Lunina, Natalia A; Agafonova, Elena V; Chekanovskaya, Lyudmila A; Dvortsov, Igor A; Berezina, Oksana V; Shedova, Ekaterina N; Kostrov, Sergey V; Velikodvorskaya, Galina A

2007-07-01

A cluster of Thermotoga neapolitana genes participating in starch degradation includes the malG gene of sugar transport protein and the aglB gene of cyclomaltodextrinase. The start and stop codons of these genes share a common overlapping sequence, aTGAtg. Here, we compared properties of expression products of three different constructs with aglB from T. neapolitana. The first expression vector contained the aglB gene linked to an upstream 90-bp 3'-terminal region of the malG gene with the stop codon overlapping with the start codon of aglB. The second construct included the isolated coding sequence of aglB with two tandem potential start codons. The expression product of this construct in Escherichia coli had two tandem Met residues at its N terminus and was characterized by low thermostability and high tendency to aggregate. In contrast, co-expression of aglB and the 3'-terminal region of malG (the first construct) resulted in AglB with only one N-terminal Met residue and a much higher specific activity of cyclomaltodextrinase. Moreover, the enzyme expressed by such a construct was more thermostable and less prone to aggregation. The third construct was the same as the second one except that it contained only one ATG start codon. The product of its expression had kinetic and other properties similar to those of the enzyme with only one N-terminal Met residue.

Santa Clara de Nanay: the MAL-ED cohort in Peru.

Science.gov (United States)

Yori, Pablo Peñataro; Lee, Gwenyth; Olórtegui, Maribel Paredes; Chávez, César Banda; Flores, Julian Torres; Vasquez, Angel Orbe; Burga, Rosa; Pinedo, Silvia Rengifo; Asayag, César Ramal; Black, Robert E; Caulfield, Laura E; Kosek, Margaret

2014-11-01

The Etiology, Risk Factors and Interactions of Enteric Infections and Malnutrition and the Consequences for Child Health and Development (MAL-ED) cohort study communities in Peru are located in Loreto province, in a rural area 15 km from the city of Iquitos. This riverine population of approximately 5000 individuals is fairly representative of Loreto. The province lags behind the rest of the country in access to water and sanitation, per capita income, and key health indicators including infant mortality (43.0 vs 16.0 per 1000 nationwide) and under-5 mortality (60.6 vs 21.0 per 1000). Total fertility rates are higher than elsewhere in the country (4.3 vs 2.6). Nationwide, the prevalence of human immunodeficiency virus is estimated at 0.45%, the prevalence of tuberculosis is 117 per 100 000, and the incidence of malaria is 258 per 100 000. Stunting in this community is high, whereas acute undernutrition is relatively uncommon. The population suffers from high rates of diarrheal disease. Prevalent enteric pathogens include Ascaris, Giardia, enterotoxigenic Escherichia coli, Shigella, and Campylobacter. © The Author 2014. Published by Oxford University Press on behalf of the Infectious Diseases Society of America. All rights reserved. For Permissions, please e-mail: journals.permissions@oup.com.

La seducción del mal: crimen, arte, dictadura y poesía en "Estrella distante"

OpenAIRE

Díaz de la Cruz, Elena

2017-01-01

Trabajo de fin de Grado. Grado en Filología Hispánica. Curso académico 2016-2017 [ES]En la presente investigación se trabajará en torno al mal y su seducción a través del arte contemporáneo, la dictadura, el crimen, y todo ello envuelto en la poesía como forma de llevar a cabo la finalidad más antipoética que nos pudiéramos imaginar. El espacio “entre”, lo indefinido y el abismo va a ser el terreno donde la poesía cobra vida pero, además, crea un aura de diferentes posibilidades en torno a...

Mala praxis médica en el quirófano

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Tania Amores Agulla

Full Text Available La mala praxis médica constituye actualmente un problema global de salud, incluso en los mejores centros hospitalarios del mundo. Se consultaron 26 referencias bibliográficas nacionales e internacionales acerca del tema con el objetivo de determinar el estado actual de los errores médicos en el quirófano. El ejercicio de la medicina tiene riesgos inherentes y la naturaleza humana hace imposible que el hombre sea infalible. Los tipos de errores más frecuentes en la práctica médica son: administración equívoca de medicamentos, diagnósticos inciertos, fallas técnicas (procedimientos insuficientes, incompletos y/o incorrectos y demora en el salón de operaciones. Las causas más frecuentes engloban el cansancio, la prisa, falta de conocimientos, entre otras. La prevención es posible y son numerosas las estrategias aplicadas por los diferentes sistemas de salud: estimular el trabajo en equipo, fortalecer la capacitación del médico y personal paramédico, evitar confiar en la memoria usando listas de chequeo, estandarizar procedimientos y protocolos, crear la cultura del reporte voluntario de errores. El error debe ser utilizado como una oportunidad para aprender, para mejorar la calidad en la atención y por ende, la seguridad de los enfermos.

Revision of the Competency Standards for Occupational Therapy Driver Assessors: An overview of the evidence for the inclusion of cognitive and perceptual assessments within fitness-to-drive evaluations.

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Fields, Sally M; Unsworth, Carolyn A

2017-08-01

Determination of fitness-to-drive after illness or injury is a complex process typically requiring a comprehensive driving assessment, including off-road and on-road assessment components. The competency standards for occupational therapy driver assessors (Victoria, Australia) define the requirements for performance of a comprehensive driving assessment, and we are currently revising these. Assessment of cognitive and perceptual skills forms an important part of the off-road assessment. The aim of this systematic review of systematic reviews (known as an overview) is to identify what evidence exists for including assessment of cognitive and perceptual skills within fitness-to-drive evaluations to inform revision of the competency standards. Five electronic databases (MEDLINE, CINAHL, PsycINFO, The Cochrane Library, OT Seeker) were systematically searched. Systematic review articles were appraised by two authors for eligibility. Methodological quality was independently assessed using the AMSTAR tool. Narrative analysis was conducted to summarise the content of eligible reviews. A total of 1228 results were retrieved. Fourteen reviews met the inclusion criteria. Reviews indicated that the components of cognition and perception most frequently identified as being predictive of fitness-to-drive were executive function (n = 13), processing speed (n = 12), visuospatial skills, attention, memory and mental flexibility (n = 11). Components less indicative were perception, concentration (n = 10), praxis (n = 9), language (n = 7) and neglect (n = 6). This overview of systematic reviews supports the inclusion of assessment of a range of cognitive and perceptual skills as key elements in a comprehensive driver assessment and therefore should be included in the revised competency standards for occupational therapy driver assessors. © 2017 Occupational Therapy Australia.

A cooperative inquiry into action learning and praxis development in a community nursing module.

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Jenkins, Emrys R; Mabbett, Gaynor M; Surridge, Andrea G; Warring, Joanna; Gwynn, Elizabeth D

2009-09-01

As nurse lecturers we investigated practice development and action learning approaches aimed at enabling postregistration bachelor's- and master's-level nursing students (Community Health Studies, Nursing in the Home) to advance practice in the context of policy and professional developments. A patchwork text was used to assess summatively what students achieved (practice change/development) and how this was informed critically, via an extended epistemology. First-person inquiry supplemented by cooperative inquiry postcourse completion (including reflective discussions with 16 students and 16 practice mentors) were used to assist coresearcher constructions of meaning. A relational, tripartite approach to learning and assessment (students', teachers', and practice mentors' collective contributions) depends on continuing reflective attention. Action learning enhances interrelation of experience with dialectic thinking. The patchwork text functions to promote creative writing, evaluative thinking, and praxis development. Role modeling by all, being genuine and not just "talking" genuine, is challenging yet crucial if people are to function as mutual resources for learning.

Una fuente potencial de conflictos jurídicos: la mala praxis en materia de incorporación de la normativa en el Mercosur

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Alejandro Pastori

2014-10-01

Full Text Available Los comentarios que se desarrollan en este arÚculo, tienen por finalidad el planteo y análisis de la falta de certeza que existe en materia de vigencia de la normativa del Mercado Común del Sur (MERCOSUR, como consecuencia, esencialmente, de la mala praxis de los Estados en cumplir con las disposiciones en materia de incorporación de la normativa MERCOSUR. Esta circunstancia, que por cierto no beneficia al proceso de integración en su conjunto, se traduce en la posibilidad cierta de conflictos entre Estados o particulares, por lo que creemos de interés el estudio del tema.Aclaramos que no constituye objeto de este trabajo ahondar en el hecho comprobado de la omisión de los Estados Parte de proceder a la incorporación de las normas y en la necesidad de que activen sus procedimientos internos,a estos efectos, sino el analizar las consecuencias jurídicas de las eventuales desviaciones, por parte de éstos, en la aplicación de las disposiciones vinculadas al procedimiento de incorporación de las normas MERCOSUR. A este último aspecto únicamente es al que nos referimos entonces con la expresión "mala praxis". 

Malária durante a gravidez: efeito sobre o curso da gestação na região amazônica Impact of malaria during pregnancy in the Amazon region

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Eda Cristina da Silva Chagas

2009-09-01

Full Text Available OBJETIVO: Estimar o efeito da malária sobre o curso da gestação em mulheres na região amazônica e investigar possíveis fatores de risco nessa população. MÉTODOS: Este estudo transversal é parte de um projeto maior para estudar malária e gravidez na região amazônica. Foram incluídas gestantes com malária atendidas na Fundação de Medicina Tropical do Amazonas que responderam a entrevistas estruturadas. Dados socio-econômicos, comportamentais e clínicos foram levantados na primeira consulta relacionada a cada novo episódio de malária na gestante. Todas as gestantes foram acompanhadas ao longo de sua gestação. Foram considerados os seguintes fatores de risco para alterações no curso da gestação: idade materna menor do que 20 anos, primeira gestação, primeira infecção malárica e espécie de plasmódio infectante. RESULTADOS: Foram avaliados 535 episódios de malária em 417 gestantes, sendo 20,56% causados pelo P. falciparum, 78,69% pelo P. vivax e 0,75% pela associação dos dois parasitas. Alteração no curso da gestação foi um evento muito frequente (26,2%. Ameaça de aborto ocorreu em 49 casos (25,5%, aborto em dois (1,0%, ameaça de parto prematuro em 74 (25,1% e parto prematuro em três (1,0%. Ser primigesta e adolescente apresentou associação estatisticamente significativa com ameaça de parto prematuro e abortamento. CONCLUSÃO: A alteração no curso da gestação foi um evento muito frequente durante o episódio agudo de malária, embora a interrupção da gestação tenha tido baixa ocorrência em nossa casuística. Os resultados não evidenciaram um fator de risco de destaque, sugerindo que qualquer gestante pode apresentar ameaça de interrupção ou interrupção da gestação na vigência de episódio agudo de malária.OBJECTIVE: To estimate the impact of malaria on the course of pregnancy in women from the Amazon region and to investigate possible risk factors in this population. METHODS: This

Revising Lecture Notes: How Revision, Pauses, and Partners Affect Note Taking and Achievement

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Luo, Linlin; Kiewra, Kenneth A.; Samuelson, Lydia

2016-01-01

Note taking has been categorized as a two-stage process: the recording of notes and the review of notes. We contend that note taking might best involve a three-stage process where the missing stage is revision. This study investigated the benefits of revising lecture notes and addressed two questions: First, is revision more effective than…

Effects of the substitution of iron for cobalt on the crystal and magnetic properties of PrCo4-xFexM (M=Al and Ga)

International Nuclear Information System (INIS)

Zlotea, C.; Isnard, O.

2003-01-01

We report on the structural and magnetic properties of PrCo 4-x Fe x M where x=0-4 and M=Al and Ga. The iron solubility limit in these phases is determined by means of X-ray diffraction and scanning electron microscopy. Our study confirms that single phase samples crystallizing in the CaCu 5 -type structure are stabilized for x 5 structure but with a slight preference for the 3g site. The saturation magnetization and the Curie temperature increase upon the iron substitution. The PrCo 4-x Fe x M compounds present spin reorientation transitions, whatever the substituting M and the Fe content. The substitution of iron for cobalt induces a significant increase of the spin reorientation temperature. Neutron and X-ray powder diffraction experiments as well as magnetic measurements are combined in order to clarify the effects of the presence of iron on the magnetocrystalline anisotropy and the spin reorientation transition. Finally, the magnetic phase diagrams of PrCo 4-x Fe x M (M=Al and Ga) have been determined in the whole ordered temperature range

A TIR domain variant of MyD88 adapter-like (Mal)/TIRAP results in loss of MyD88 binding and reduced TLR2/TLR4 signaling.

NARCIS (Netherlands)

Nagpal, K.; Plantinga, T.S.; Wong, J.; Monks, B.G.; Gay, N.J.; Netea, M.G.; Fitzgerald, K.A.; Golenbock, D.

2009-01-01

The adapter protein MyD88 adapter-like (Mal), encoded by TIR-domain containing adapter protein (Tirap) (MIM 606252), is the most polymorphic of the five adapter proteins involved in Toll-like receptor signaling, harboring eight non-synonymous single nucleotide polymorphisms in its coding region. We

Mal de Debarquement Syndrome: A Rare Entity—A Case Report and Review of the Literature

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Veronica Nwagwu

2015-01-01

Full Text Available Mal de Debarquement Syndrome (MDS is a rare, understudied, underdiagnosed, and self-limiting condition. Etiology and incidence are unknown. It is characterized by abnormal sensation of motion/balance reported after travel by air, land, and sea; being reexposed to motion/activity relieves it. Symptoms may last from minutes to years. Workup though required reveals no findings; it is a diagnosis of exclusion. While no efficacious treatment exists, amitriptyline and benzodiazepines as well as supportive therapy have proved to be useful. We have described a 40-year-old Caucasian female who presented for the evaluation of persistent rocking and swaying sensation after a ship cruise which lasted for one week. Patient was treated with benzodiazepines after extensive workup and is now stable. A high index of suspicion is required to make a diagnosis.

Malaria diagnosis and treatment under the strategy of the integrated management of childhood illness (IMCI): relevance of laboratory support from the rapid immunochromatographic tests of ICT Malaria P.f/P.v and OptiMal.

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Tarimo, D S; Minjas, J N; Bygbjerg, I C

2001-07-01

The algorithm developed for the integrated management of childhood illness (IMCI) provides guidelines for the treatment of paediatric malaria. In areas where malaria is endemic, for example, the IMCI strategy may indicate that children who present with fever, a recent history of fever and/or pallor should receive antimalarial chemotherapy. In many holo-endemic areas, it is unclear whether laboratory tests to confirm that such signs are the result of malaria would be very relevant or useful. Children from a holo-endemic region of Tanzania were therefore checked for malarial parasites by microscopy and by using two rapid immunochromatographic tests (RIT) for the diagnosis of malaria (ICT Malaria P.f/P.v and OptiMal. At the time they were tested, each of these children had been targeted for antimalarial treatment (following the IMCI strategy) because of fever and/or pallor. Only 70% of the 395 children classified to receive antimalarial drugs by the IMCI algorithm had malarial parasitaemias (68.4% had Plasmodium falciparum trophozoites, 1.3% only P. falciparum gametocytes, 0.3% P. ovale and 0.3% P. malariae). As indicators of P. falciparum trophozoites in the peripheral blood, fever had a sensitivity of 93.0% and a specificity of 15.5% whereas pallor had a sensitivity of 72.2% and a specificity of 50.8%. The RIT both had very high corresponding sensitivities (of 100.0% for the ICT and 94.0% for OptiMal) but the specificity of the ICT (74.0%) was significantly lower than that for OptiMal (100.0%). Fever and pallor were significantly associated with the P. falciparum asexual parasitaemias that equalled or exceeded the threshold intensity (2000/microl) that has the optimum sensitivity and specificity for the definition of a malarial episode. Diagnostic likelihood ratios (DLR) showed that a positive result in the OptiMal test (DLR = infinity) was a better indication of malaria than a positive result in the ICT (DLR = 3.85). In fact, OptiMal had diagnostic reliability (0

Analysis of Praxis physics subject assessment examinees and performance: Who are our prospective physics teachers?

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Shah, Lisa; Hao, Jie; Rodriguez, Christian A.; Fallin, Rebekah; Linenberger-Cortes, Kimberly; Ray, Herman E.; Rushton, Gregory T.

2018-06-01

A generally agreed upon tenant of the physics teaching community is the centrality of subject-specific expertise in effective teaching. However, studies which assess the content knowledge of incoming K-12 physics teachers in the U.S. have not yet been reported. Similarly lacking are studies on if or how the demographic makeup of aspiring physics educators is different from previously reported analyses of the actual high school physics teaching workforce. Here we present findings about the demographics and subject knowledge of prospective high school physics teachers using data from Praxis physics subject assessments administered between 2006 and 2016. Our analysis reveals significant variations in exam participation and performance between men and women, as well as those with different undergraduate majors and academic performance over the past decade. Findings from this work inform understandings and decisions about the quality, recruitment, and preparation of the high school physics teaching workforce.

Acetabular Cup Revision.

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Kim, Young-Ho

2017-09-01

The use of acetabular cup revision arthroplasty is on the rise as demands for total hip arthroplasty, improved life expectancies, and the need for individual activity increase. For an acetabular cup revision to be successful, the cup should gain stable fixation within the remaining supportive bone of the acetabulum. Since the patient's remaining supportive acetabular bone stock plays an important role in the success of revision, accurate classification of the degree of acetabular bone defect is necessary. The Paprosky classification system is most commonly used when determining the location and degree of acetabular bone loss. Common treatment options include: acetabular liner exchange, high hip center, oblong cup, trabecular metal cup with augment, bipolar cup, bulk structural graft, cemented cup, uncemented cup including jumbo cup, acetabular reinforcement device (cage), trabecular metal cup cage. The optimal treatment option is dependent upon the degree of the discontinuity, the amount of available bone stock and the likelihood of achieving stable fixation upon supportive host bone. To achieve successful acetabular cup revision, accurate evaluation of bone defect preoperatively and intraoperatively, proper choice of method of acetabular revision according to the evaluation of acetabular bone deficiency, proper technique to get primary stability of implant such as precise grafting technique, and stable fixation of implant are mandatory.

Failure of aseptic revision total knee arthroplasties.

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Leta, Tesfaye H; Lygre, Stein Håkon L; Skredderstuen, Arne; Hallan, Geir; Furnes, Ove

2015-02-01

In Norway, the proportion of revision knee arthroplasties increased from 6.9% in 1994 to 8.5% in 2011. However, there is limited information on the epidemiology and causes of subsequent failure of revision knee arthroplasty. We therefore studied survival rate and determined the modes of failure of aseptic revision total knee arthroplasties. This study was based on 1,016 aseptic revision total knee arthroplasties reported to the Norwegian Arthroplasty Register between 1994 and 2011. Revisions done for infections were not included. Kaplan-Meier and Cox regression analyses were used to assess the survival rate and the relative risk of re-revision with all causes of re-revision as endpoint. 145 knees failed after revision total knee arthroplasty. Deep infection was the most frequent cause of re-revision (28%), followed by instability (26%), loose tibial component (17%), and pain (10%). The cumulative survival rate for revision total knee arthroplasties was 85% at 5 years, 78% at 10 years, and 71% at 15 years. Revision total knee arthroplasties with exchange of the femoral or tibial component exclusively had a higher risk of re-revision (RR = 1.7) than those with exchange of the whole prosthesis. The risk of re-revision was higher for men (RR = 2.0) and for patients aged less than 60 years (RR = 1.6). In terms of implant survival, revision of the whole implant was better than revision of 1 component only. Young age and male sex were risk factors for re-revision. Deep infection was the most frequent cause of failure of revision of aseptic total knee arthroplasties.

O Enigma do Mal: uma leitura do 'De casu diaboli'de Santo Anselmo (The enigma of evil: a reading of St. Anselm’s De casu diaboli - DOI: 10.5752/P.2175-5841.2013v11n32p1551

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Manoel Luís Cardoso Vasconcellos

2013-12-01

Full Text Available O presente artigo quer investigar o problema do mal na perspectiva de Santo Anselmo, tomando como ponto de partida sua obra De casu diaboli, onde o tema é abordado, a partir da íntima ligação entre mal e pecado. Ao enfocar o mal na perspectiva da queda diabólica, o Doutor Magnífico intenta mostrar a conexão entre vontade, liberdade e justiça. Sua preocupação é investigar o significado moral da má escolha, realizada por uma criatura racional e puramente espiritual, feita boa e para ser boa. O pecado, consoante o autor, não está em almejar a felicidade, pois tal desejo é dádiva divina; o mal praticado pelo anjo está, precisamente, em querer a felicidade fora da justiça, isto é, ao querer ser feliz, ele foi de encontro ao que ele deveria ser: quis ser semelhante a Deus, extrapolando a sua própria natureza, pois ele desejou algo que, enquanto criatura, não caberia a ele almejar. Este é o ponto de partida para analisar o mal e sua mais dramática consequência, o sofrimento. Palavras-chave: Mal. Vontade. Justiça. Anselmo.   Abstract This article aims to investigate the problem of evil in Saint Anselm, especially in his treatise De casu diaboli. He approaches this issue from the close connection between evil and sin. Upon analyzing evil from the diabolic fall perspective, Dr. Magnificent tries to establish a connection between will, freedom and justice. This text investigates the moral meaning of misconduct, carried out by a rational and purely spiritual creature that was created good and meant to be good. Seeking for happiness is not itself a sin, according to the author, for such a wish is a gift from God. The evil done by the angel lies in the act of wanting happiness without justice, that is, on wanting to be happy, the angel contradicted what he was supposed to be: he wanted to be like God, transcending his own nature, as he wished for something that, as a creature, he was not fit to wish for. This is the starting point to

DNA hypermethylation and decreased mRNA expression of MAL, PRIMA1, PTGDR and SFRP1 in colorectal adenoma and cancer

International Nuclear Information System (INIS)

Kalmár, Alexandra; Péterfia, Bálint; Hollósi, Péter; Galamb, Orsolya; Spisák, Sándor; Wichmann, Barnabás; Bodor, András; Tóth, Kinga; Patai, Árpád V.; Valcz, Gábor; Nagy, Zsófia Brigitta; Kubák, Vivien; Tulassay, Zsolt; Kovalszky, Ilona; Molnár, Béla

2015-01-01

Colorectal cancer (CRC) development is accompanied by changes in expression for several genes; but the details of the underlying regulatory procesess remain unknown. Our aims were to assess the role of epigenetic processes in tumour formation and to identify characteristic DNA methylation and miRNA alterations in the colorectal adenoma-carcinoma sequence. Whole genome expression profiling was performed on colonic biopsy samples (49 healthy normal, 49 colorectal adenoma (AD), 49 CRC); on laser capture microdissected (LCM) epithelial and stromal cells from 6 CRC-normal adjacent tissue (NAT) samples pairs, and on demethylated human CRC cell lines using HGU133 Plus 2.0 microarrays (Affymetrix). Methylation status of genes with gradually altering expression along the AD-CRC sequence was further analysed on 10–10 macrodissected and 5–5 LCM samples from healthy colon, from adenoma and from CRC biopsy samples using bisulfite-sequencing PCR (BS-PCR) followed by pyrosequencing. In silico miRNA prediction for the selected genes was performed with miRWALK algorithm, miRNA expression was analysed on 3 CRC-NAT sample pairs and 3 adenoma tissue samples using the Human Panel I + II (Exiqon). SFRP1 immunohistochemistry experiments were performed. A set of transcripts (18 genes including MAL, SFRP1, SULT1A1, PRIMA1, PTGDR) showed decreasing expression (p < 0.01) in the biopsy samples along the adenoma-carcinoma sequence. Three of those (COL1A2, SFRP2, SOCS3) showed hypermethylation and THBS2 showed hypomethylation both in AD and in CRC samples compared to NAT, while BCL2, PRIMA1 and PTGDR showed hypermethylation only in the CRC group. miR-21 was found to be significantly (p < 0.01) upregulated in adenoma and tumour samples compared to the healthy colonic tissue controls and could explain the altered expression of genes for which DNA methylation changes do not appear to play role (e.g. BCL2, MAL, PTGS2). Demethylation treatment could upregulate gene expression of genes that were

Biologia de anofelinos amazônicos: XII. Ocorrência de espécies de Anopheles, dinâmica da transmissão e controle da malária na zona urbana de Ariquemes (Rondônia

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Wanderli Pedro Tadei

1988-06-01

Full Text Available Dados sobre o grau de incidência e distribuição de espécies Anopheles, em Ariquemes (RO, evidenciaram que a diversidade é maior na periferia da cidade e que Anopheles darlingi é registrada em praticamente todas as localidades de coleta. O inquérito entomológico revelou níveis diferentes de penetração da espécie na área urbana, podendo-se constatar que os Setores 1 e 3 são áreas livres de malária; Setores 2 e 4 mostram riscos na periferia; e a Área Industrial e Setor de Áreas Especiais, Conjunto BNH, Setor 5 e Vila Velha constituem áreas de alto risco da malária. Nestes últimos, os índices de mosquitos por homem/hora foram os mais elevados, observando-se variações no decorrer das amostragens e conforme a localização da área urbana. Medidas de densidade populacional revelaram mudanças estacionais, sendo os menores valores registrados no período de inverno. A transmissão da malária é discutida, considerando-se: 1 o papel da estrutura física da cidade, na época da fundação, 2 os igarapés que margeam a área urbana e suas relações com o ciclo de desenvolvimento dos anofelinos, 3 os padrões comportamentais da atividade de picar das espécies correlacionados a ambientes naturais e às áreas ecologicamente alteradas, e 4 a importância do manuseio ambiental no controle da malária, para redução da densidade populacional. Para conter o processo migratório do vetor é proposto um cinturão de proteção à cidade, constituído de mata não densa, incluindo também proteção biológica para incentivar a zoofilia dos anofelinos. Os resultados de infecção natural, obtidos em áreas de autoctonia da malária, permitem citar A. darlingi como vetor, sendo discutida a possibilidade de que outras espécies estejam envolvidas na transmissão.

NOTES ON THE APPLICATION OF THE THEORY AND PRAXIS TRAINING CURRICULUM FOR COMMUNICATION AND CULTURE OF PEACE

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Rocio Belandria Cerdeira

2011-04-01

Full Text Available The objective of this research is to present theoretical considerations on the application of the Theory and Praxis Training Curriculum for Communication and Culture of Peace. The theoretical study is descriptive and documentary. In the first stage were analyzed and discussed theoretical material related to the category of analysis. In a second stage developed a series of notes and reflective-critical comments, which point to consider hybrid forms of theories when designing curricular training in Communication and Culture of Peace. In conclusion, we feel the need to open the Multidisciplinary discussion on the subject, where the curriculum, the humanistic, existential communicational and bring new ways of learning, being, doing, living together, but above all to communicate, in order to take a step to build a communicative culture.

Bibliocable. Revised Edition.

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Cable Television Information Center, Washington, DC.

This selective, annotated bibliography is a revision of the original published in 1972 (ED 071 402). Some 104 books, articles, and reports included here deal with access, applications, franchising, regulation, technology, and other aspects of cable television. The listings are of two types in each category. First are revisions of the original…

Estudo de dose adequada da droga RO42-1611 (Arteflene) no tratamento da malária por Plasmodium falciparum

OpenAIRE

SILVA, Rita do Socorro Uchôa

1997-01-01

A resistência crescente do P. falciparum aos antimaláricos habitualmente empregados, torna urgente a avaliação de novas drogas. O Ro 42-1611 é um antimalárico derivado da planta chinesa Arlabotrys uncinatus. Usado apenas na África em três trabalhos no tratamento da malária por P. falciparum, tem sua ação desconhecida em sul-americanos com esta doença. Apesar do efeito antimalárico ter sido comprovado, ainda não se encontrou a dose adequada para o tratamento supressivo do P. falciparum. Avalia...

ÉTICA, PRAXIS Y GENERICIDAD EL EMPLAZAMIENTO DE LA FILOSOFÍA MORAL EN EL MARXISMO

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Jordi Magnet Colomer

2013-06-01

Full Text Available La construcción de una teoría ética de inspiración marxiana demanda una identificación de los intereses morales del movimiento emancipatorio con la ética; sin embargo, en no pocas ocasiones ha prevalecido la identificación de éstos con códigos de tipo consuetudinario. El primer punto aborda esta problemática junto a la refutación de los argumentos contrarios a elaborar una ética desde el marxismo. En la siguiente sección se lleva a cabo una discusión en torno la noción normativa y descriptiva de la praxis, seguido de un análisis del rol desempeñado por el concepto-valor genericidad en el humanismo marxista. Ya por último, vienen a apuntarse las directrices fundamentales del giro ético-comunicativo emprendido por J. Habermas y A. Wellmer en la Teoría Crítica.

How much change is true change?: The smallest detectable difference of the Preschool Imitation and Praxis Scale (PIPS) in preschoolers with intellectual disabilities of heterogeneous aetiology

OpenAIRE

Vanvuchelen, Marleen; Vochten, Christine

2011-01-01

The teaching of imitation skills is often the first step in interventions for young learners with intellectual disabilities. The main goal of this study was to determine the smallest detectable difference (SDD) at 95% confidence of the Preschool Imitation and Praxis Scale(PIPS) in preschoolers with intellectual disabilities. Two raters independently scored videotapes of the imitation performance of 44 preschoolers (27 with Down syndrome, 10 with Non-Specific Mental Retardation and 7 with Low-...

Keeping gay and bisexual men safe: The arena of HIV prevention science and praxis.

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Green, Adam Isaiah

2016-04-01

Abstract In this article, I draw from an ongoing ethnographic study of HIV prevention for gay, bisexual, and 'men who have sex with men' to develop an institutional analysis of HIV behavioral intervention science and praxis. I approach this analysis through the lens of the social worlds framework, focusing on the institutional arena in which HIV behavioral interventions are devised and executed. Toward this end, I focus on two fundamental points of contention that lie at the heart of the prevention enterprise and put its social organization in high relief: (1) conceptions of health and lifestyle practices and (2) attributions of expertise. These core contentions reveal less the steady advance of normal science than an arena of actors ensconced in boundary work and jurisdictional struggles over how to engineer behavior change and reduce the scale of the HIV epidemic. Their resolution, I argue, has occurred in a historically contingent process determined by the political economy of the US HIV prevention arena and the differential structural location of its social worlds.

O mal-estar na modernidade e a psicanálise: a psicanálise à prova do social The discontent in modernity and psychoanalysis: social-proof psychoanalysis

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Joel Birman

2005-01-01

Full Text Available O artigo tem a intenção de indicar a presença de dois discursos teóricos opostos em Freud, no que concerne às relações entre sujeito e modernidade. Pretende-se demonstrar que na sua segunda versão, desenvolvida em Mal-estar na civilização, o discurso psicanalítico realizou uma crítica sistemática de sua versão inicial, esboçada em "Moral sexual 'civilizada' e a doença nervosa dos tempos modernos". Pela construção dos conceitos de desamparo e de mal-estar, o discurso freudiano colocou então a psicanálise à prova do social. Além disso, indica que aquela pôde construir uma leitura sobre a modernidade, ao lado das que foram realizadas por Weber e Heidegger. Finalmente, esse percurso tem ainda a finalidade de pensar a crise da psicanálise na atualidade, nas novas condições do mal-estar na modernidade.The article aims at showing the presence of two opposing theoretical discourses in Freud, in what concerns the relationship between the subject and modemity. It intends to demonstrate that in its second version, developed in Malaise dansia civilisation, the analytical discourse achieved a systematic critical review of its initial version outlined in "La morale sexuelle 'civilisée' et la maladie nerveuse des temps modemes". Through constructing the concepts of discontent and distress, the Freudian discourse thus made psychoanalysis social-proof. ln addition, it indicates that psychoanalysis was able to build a reading of modemity other than those made by Weber and Heidegger. Finally, this joumey also aims at thinking over the present crisis of psychoanalysis within the new conditions of discontent in modemity.

Albertet, “En amor trob tantz de mals seignoratges” (BdT 16.13

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Francesca Sanguineti

2008-12-01

Full Text Available The article provides a commentary and a new critical edition of Albertet’s poem “En amor trob tantz de mals seignoratges”, in which the troubadour praises some of the most courtly ladies of his time. The poem can be linked to the genre of the collective eulogy, where the enumerated ladies are praised essentially for political reasons, since the commendation is clearly addressed to the men hidden behind them: famous specimena of this genre are the ‘tournoiements des dames’ by Huon d’Oisy and Richard de Semilli and Raimbaut de Vaqueiras’ “Carros” (BdT 392.32. Albertet’s song starts with a misogynic tone, since the poet declares that celebrating or loving ladies is worthless, given their immoral behaviour, and with a polemic against the strict rules of courtly love. This misogyny, as is further discovered, is a rhetorical device to praise women as well as a tool to renew the genre of the love song from a thematic point of view.

Guidance document for revision of DOE Order 5820.2A, Radioactive Waste Technical Support Program. Revision 1

Energy Technology Data Exchange (ETDEWEB)

Kudera, D.E.; McMurtrey, C.D.; Meagher, B.G.

1993-04-01

This document provides guidance for the revision of DOE Order 5820.2A, ``Radioactive Waste Management.`` Technical Working Groups have been established and are responsible for writing the revised order. The Technical Working Groups will use this document as a reference for polices and procedures that have been established for the revision process. The overall intent of this guidance is to outline how the order will be revised and how the revision process will be managed. In addition, this document outlines technical issues considered for inclusion by a Department of Energy Steering Committee.

Ideological leaning and praxis of housing co-operatives in South Africa: Matters arising

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Richard Jimoh

2013-06-01

Full Text Available Social movements came about as a result of dissatisfaction felt by society from the status quo. They present their grievances through demonstrations, strikes, riots, occupation of land, boycott of business or by the development of social and economic alternatives such as self-help schemes or saving clubs. In South Africa, people join housing co-operatives because it takes a long time to wait for the Reconstruction Development Project (RDP houses promised by the Government. The leaning of 5 housing co-operatives was examined within the context of ideology and praxis that are components of triad model. This was done through multi-case study whereby the chairpersons of the housing co-operatives were interviewed using structured interview format. Findings from the study indicated that all the housing co-operatives were not open and voluntary; also, the housing co-operatives were not administered the same way. In all, efforts were put in by the housing co-operatives in engendering the ideology of co-operatives on one hand and the government on the other hand in providing the necessary subsidy so that the gap in the housing deficit could be bridged since this fitted its policy on housing. 

Ideological leaning and praxis of housing co-operatives in South Africa: Matters arising

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Richard Jimoh

2013-06-01

Full Text Available Social movements came about as a result of dissatisfaction felt by society from the status quo. They present their grievances through demonstrations, strikes, riots, occupation of land, boycott of business or by the development of social and economic alternatives such as self-help schemes or saving clubs. In South Africa, people join housing co-operatives because it takes a long time to wait for the Reconstruction Development Project (RDP houses promised by the Government. The leaning of 5 housing co-operatives was examined within the context of ideology and praxis that are components of triad model. This was done through multi-case study whereby the chairpersons of the housing co-operatives were interviewed using structured interview format. Findings from the study indicated that all the housing co-operatives were not open and voluntary; also, the housing co-operatives were not administered the same way. In all, efforts were put in by the housing co-operatives in engendering the ideology of co-operatives on one hand and the government on the other hand in providing the necessary subsidy so that the gap in the housing deficit could be bridged since this fitted its policy on housing.

Background and managerial practice of nurses: paths for transforming praxis La formación y la práctica gerencial del enfermero: caminos para una praxis transformadora A formação e a prática gerencial do enfermeiro: caminhos para a práxis transformadora

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Zélia Marilda Rodrigues Resck

2008-02-01

Full Text Available Qualitative research using a dialectics view; the objective is to analyze the demands and the expectations from the setting of managerial practices in view of the Pedagogical Project and the strategies which may or may not favor the transforming praxis. It involves 11 students, 12 professors, and 12 service nurses who are the participants in the teaching-learning process of managerial knowledge, in the interceding space, in the fields of practice and in the curricular training programs, both in the hospital environment and in the basic health services and of the Nursing graduation course from a Federal University, from the city of Alfenas-MG. It uses the collecting technique by focal group and the analysis of the contents is subsided by two great discussions: background and work. The results point that the nurse's background and praxis must go through the work processes in the caring, managerial and educative dimensions as well as in the scientific investigation, building paths for the development of competences, in the teaching and service interaction, following the current National Curriculum Guidelines.Se trata de una investigación con enfoque cualitativo dentro de la perspectiva dialéctica; siendo el objetivo analizar las demandas y las expectativas de las prácticas gerenciales frente al Proyecto Pedagógico, así como las estrategias que favorecen la praxis transformadora. Participaron 11 alumnos, 12 docentes y 12 enfermeros del servicio, participantes del proceso enseñanza- aprendizaje en el saber gerencial del curso de Pre-grado en Enfermería de la Institución Federal de Enseñanza Superior de Alfenas-MG, en el lugar de intervención, en los campos prácticos y práctico curriculares del hospital dentro los servicios básicos. La recolección de datos fue a través del grupo focal y el análisis de contenido fue subsidiado por dos grandes vertientes: formación y actuación. Los resultados indican que la formación y la praxis del

Praxis política en y en torno a Retrato de la Lozana andaluza de Francisco Delicado

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María Cecilia Pavón

2014-12-01

Full Text Available Retrato de la Lozana andaluza written by Francisco Delicado presents a peculiar relation between word and image. To begin with, this is done through the introduction of engravings which accompany each Mamotreto (Chapter, and then through the use of a narrative procedure that we may call “audiovisual technique”. Moreover, the transposition of History to films and to television during the 20th Century is added to this complex relation. The purpose of this work is to lay the theoretical foundations to analyse the relations between textual and iconic discourse within the framework of key concepts from Georges Didi-Huberman´s theory, such as “writing in exile”, “montage”, “deconstruction” and “re-montage” and to specify the implications of the political praxis in and around Retrato de la Lozana andaluza

Contribuição ao estudo do mal de cadeiras na Ilha de Marajó

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Geth Jansen

1941-01-01

Full Text Available Como resultado de inspeções feitas à ilha de Marajó o autor assinala: 1º O mal de cadeiras continua existindo na ilha de Marajó sob a forma enzoótica, ao contrário do que pensavam os criadores, julgando-o extinto. As doenças designadas por estes como "barriga inchada" e "mormo seco", responsaveis pela grande mortalidade dos equinos, foram identificadas pelo autor como tal de cadeiras. 2º O autor considera indispensável para a pesquisa do trypanosoma o processo de inoculação em animais de laboratório, tendo utilizado para esse fim camondongos e ratos brancos. 3º Os surtos epizoóticos anuais coincidem com a época das chuvas, ocasião em que surgem os insetos hematófagos, o que faz pensar no papel desses últimos como transmissores. 4º Os cavalos podem atravessar o ano com trypanosomas no sangue e em estado de saude aparente, constituindo assim depositários do mal de cadeiras. 5º O extermínio da capivara, em consequência do seu aproveitamento econômico não modificou o carater endêmico da doença na ilha de Marajó. 6º O autor observou que os trypanosomas no tubo digestivo de Stomoxys e Tabanideos, ao cabo de 8 horas, apresentavam com movimentos diminuidos e em formas arrendondadas, não conseguindo inoculações positivas com esse material. 7º A saliva de um morcego do gênero Desmodus, que se infectou no laboratório, alimentando-se em animal doente, colhida de modo a evitar lesões da mucosa e consequente contaminação pelos trypanosomas do sangue circulante, mostrou-se incapaz de infectar, por inoculação, animais sensiveis. Este mesmo morcego não transmitiu a doença a um cão, o qual sugou durante 80 dias. Recentemente (1941 empregando um exemplar do gênero Desmodus, também infectado experimentalmente por alimentação em animal de laboratório, conseguimos transmitir o Trypanosoma equinum a uma cobaia normal. Este assunto será ventilado posteriormente.

Evaluation of an anti-p185{sup HER2} (scFv-C{sub H}2-C{sub H}3){sub 2} fragment following radioiodination using two different residualizing labels: SGMIB and IB-Mal-D-GEEEK

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Vaidyanathan, Ganesan [Duke University Medical Center, Durham, NC 27710 (United States)], E-mail: ganesan.v@duke.edu; Jestin, Emmanuelle [Duke University Medical Center, Durham, NC 27710 (United States); Olafsen, Tove; Wu, Anna M. [Department of Molecular and Medical Pharmacology, Crump Institute for Molecular Imaging, David Geffen School of Medicine at University of California Los Angeles, Los Angeles, CA 90095 (United States); Zalutsky, Michael R. [Duke University Medical Center, Durham, NC 27710 (United States)

2009-08-15

Introduction: A 105-kDa double mutant single-chain Fv-Fc fragment (scFv-Fc DM) derived from the anti-p185{sup HER2} hu4D5v8 antibody (trastuzumab; Herceptin) has been described recently. The goal of this study was to investigate whether improved tumor targeting could be achieved with this fragment through the use of residualizing radioiodination methods. Methods: The scFv-Fc DM fragment was radioiodinated using N-succinimidyl 4-guanidinomethyl 3-[{sup 131}I]iodobenzoate ([{sup 131}I]SGMIB) and N{sup {epsilon}}-(3-[{sup 131}I]iodobenzoyl)-Lys{sup 5}-N{sup {alpha}}- maleimido-Gly{sup 1}-GEEEK ([{sup 131}I]IB-Mal-D-GEEEK), two residualizing radioiodination agents that have been used successfully with intact antibodies. Paired-label internalization assays of the labeled fragments were performed in vitro using MCF7 human breast cancer cells transfected to express HER2 (MCF7-HER2); comparisons were made to scFv-Fc DM directly radioiodinated using Iodogen. The tissue distribution of the scFv-Fc DM labeled with [{sup 125}I]IB-Mal-D-GEEEK and [{sup 131}I]SGMIB was compared in athymic mice bearing MCF7-HER2 xenografts. Results: The scFv-Fc DM fragment was labeled with [{sup 131}I]SGMIB and [{sup 131}I]IB-Mal-D-GEEEK in conjugation yields of 53% and 25%, respectively, with preservation of immunoreactivity for HER2. Internalization assays indicated that labeling via SGMIB resulted in a 1.6- to 3.5-fold higher (P<.05) retention of radioactivity, compared to that from the directly labeled fragment, in HER2-expressing cells during a 24-h observation period. Likewise, the amount of radioactivity retained in cells from the IB-Mal-D-GEEEK-labeled fragment was 1.4- to 3.3-fold higher (P<.05). Tumor uptake of radioiodine activity in athymic mice bearing MCF7-HER2 xenografts in vivo was significantly higher for the [{sup 125}I]IB-Mal-D-GEEEK-labeled scFv-Fc DM fragment compared with that of the [{sup 131}I]SGMIB-labeled fragment, particularly at later time points. The uptake of {sup

La filosofía como praxis La idea de superación mundana de la filosofía en Marx

OpenAIRE

Grueso, Delfín Ignacio

2008-01-01

Cuando Marx dice: “Los filósofos hasta ahora se han dedicado a interpretar el mundo en varios sentidos, cuando de lo que se trata es de cambiarlo”, ¿está sugiriendo superar la filosofía o abrirnos a una nueva forma de filosofía? ¿Qué tiene, entonces, de filosófica la obra de Marx y qué futuro le aguarda a la filosofía, según él? ¿Es su obra sólo posible gracias a la muerte de la filosofía? Y el concepto de praxis ¿qué tiene que ver con la visión marxiana de la filosofía?

Retardo no crescimento intrauterino, baixo peso ao nascer e prematuridade em recém-nascidos de grávidas com malária, na Colômbia Intrauterine growth retardation, low birth weight and prematurity in neonates of pregnant women with malaria in Colombia

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Alberto Tobón-Castaño

2011-06-01

Full Text Available INTRODUÇÃO: É frequente a associação da malária com complicações como prematuridade, retardo no crescimento intrauterino, baixo peso ao nascer e mortalidade infantil, efeitos pouco estudados em áreas hipoendêmicas para malaria. O objetivo deste estudo foi analisar a relação da malária gestacional com estes efeitos em recém-nascidosnuma região endêmica para malária na Colômbia, entre 1993 e 2007. MÉTODOS: Foram estudadas as características em 1.716 recém-nascidos num estudo de coorte. Fez-se seguimento em 394 gestantes com malária (27% por Plasmodium falciparum e 73% por P. vivax e 1.322 sem malária. RESULTADOS: Foi encontrada uma relação entre a exposição à malária na gestação e o risco maior de baixo peso ao nascer (RR = 1,37; 1,03-1,83, assim como estatura baixa (RR = 1,52; 1,25-1,85, retardo no crescimento intrauterino (RR = 1,29; 1,0-1,66 e prematuridade (RR = 1,68; 1,3-2,17. A frequência de nascimentos prematuros foi maior nas mães com malária por P. falciparum (77% que aquelas com P. vivax (RR = 1,77; IC 95%: 1,2-2,6. CONCLUSÕES: O baixo peso ao nascer e o retardo no crescimento foi associado com malária na gestação na Colômbia. A infecção por P. vivax foi relacionada com efeitos adversos sobre o recém-nascido, de modo semelhante em relação ao P. falciparum.INTRODUCTION: Association between malaria and pregnancy complications, such as prematurity, intrauterine growth restriction, low birthweight and infant mortality has been reported. These effects have been studied widely in areas hyperendemic for malaria, but studies in low-endemic areas are scarce. The study investigated the relation between gestational malaria and low birthweight and intrauterine growth retardation in neonates of a malarial endemic region in Colombia, between 1993 and 2007. METHODS: The pattern of development in 1,716 neonates of women with and without malaria infection during pregnancy was evaluated in a cohort study. A

Necropsia e mortalidade por causa mal definida no Estado de São Paulo, Brasil Autopsy and ill-defined cause of death in the state of São Paulo, Brazil

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Mauro Abrahão Rozman

2006-11-01

Full Text Available OBJETIVO: Investigar a proporção de mortes por causa mal definida no Estado de São Paulo entre 1980 e 2002, considerando a influência da realização de necropsia nessa proporção. MÉTODO: O número de óbitos foi obtido do Ministério da Saúde. Dividiu-se o Estado de São Paulo em três áreas: 1 municípios com serviço de verificação de óbitos (SVO, que pode realizar necropsias; 2 municípios sem SVO; e 3 Baixada Santista, região onde houve um aumento marcante na proporção de mortes por causa mal definida entre 1980 e 1995. O impacto das necropsias na proporção de óbitos por causa mal definida foi medido com base na classificação da causa de óbito pelo primeiro médico avaliador (aquele que encaminhou o caso para o SVO para necropsia ou que preencheu a declaração de óbito sem encaminhar o caso. Os óbitos por causas externas foram excluídos por ter necropsia obrigatória. Foram avaliadas as proporções 1 de casos classificados como de causa mal definida pelo primeiro avaliador; 2 de necropsias no total de óbitos excluindo causas externas; e 3 de óbitos com causa esclarecida por necropsia entre os classificados como de causa mal definida pelo primeiro avaliador. RESULTADOS: A proporção de óbitos classificados como de causa mal definida pelo primeiro avaliador aumentou entre 1980 e 2002 em todas as áreas: nos municípios com SVO, nos municípios sem SVO e na Baixada Santista. Para o Estado de São Paulo como um todo, o aumento foi de quase 30% no período de 1980 a 2002. Para o período de 1998 a 2002, a proporção média de necropsias no total de óbitos excluindo causas externas foi de 21,2, 6,4 e 2,6%, respectivamente, nas áreas com e sem SVO e na Baixada Santista. Entre 1998 e 2002, a proporção de óbitos com causa mal definida esclarecidos pela necropsia foi de 92,9 nas áreas com SVO, 32,5 nas áreas sem SVO e 10,7% na Baixada Santista. CONCLUSÕES: A realização de necropsias explica a diferença na

Unravelling Local Atomic Order of the Anionic Sublattice in M(Al1-x Gax )4 with M=Sr and Ba by Using NMR Spectroscopy and Quantum Mechanical Modelling.

Science.gov (United States)

Pecher, Oliver; Mausolf, Bernhard; Peters, Volker; Lamberts, Kevin; Korthaus, Alexander; Haarmann, Frank

2016-12-05

The quasibinary section of the intermetallic phases MAl 4 and MGa 4 with M=Sr and Ba have been characterised by means of X-ray diffraction (XRD) studies and differential thermal analysis. The binary phases show complete miscibility and form solid solutions M(Al 1-x Ga x ) 4 with M=Sr and Ba. These structures crystallise in the BaAl 4 structure type with four- and five-bonded Al and/or Ga atoms (denoted as Al(4b), Al(5b), Ga(4b), and Ga(5b), respectively) that form a polyanionic Al/Ga sublattice. Solid state 27 Al NMR spectroscopic analysis and quantum mechanical (QM) calculations were applied to study the bonding of the Al centres and the influence of Al/Ga substitution, especially in the regimes with low degrees of substitution. M(Al 1-x Ga x ) 4 with M=Sr and Ba and 0.925≤x≤0.975 can be described as a matrix of the binary majority compound in which a low amount of the Ga atoms has been substituted by Al atoms. In good agreement with the QM calculations, 27 Al NMR investigations and single crystal XRD studies prove a preferred occupancy of Al(4b) for these substitution regimes. Furthermore, two different local Al environments were found, namely isolated Al(4b1) atoms and Al(4b2), due to the formation of Al(4b)-Al(4b) pairs besides isolated Al(4b) atoms within the polyanionic sublattice. QM calculations of the electric field gradient (EFG) using superlattice structures under periodic boundary conditions are in good agreement with the NMR spectroscopic results. © 2016 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim.

José Gestoso y Pérez. Teoría y Praxis de la Conservación

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Mª Dolores Ruiz de Lacanal Ruiz-Mateos

2013-12-01

Full Text Available El objetivo de este artículo es hacer una reflexión sobre las aportaciones que José Gestoso y Pérez (1852-1917 realiza a la teoría y la praxis de la conservación. Persona de gran prestigio y mérito, desarrolló su labor profesional en Sevilla a mediados del siglo XIX y principios del siglo XX y ha sido objeto de numerosas investigaciones. Tras la lectura de los estudios, que le resaltan como un referente claro de la cultura sevillana en sus múltiples manifestaciones, (Historia y crítica del Arte, Arqueología, Archivística, etc., este artículo concentra la atención en sus propios textos, para descubrir que constituyen un conjunto coherente y estructurado de conocimientos teóricos y prácticos, aportan unos objetivos definidos y una metodología con recursos y estrategias, que son claros antecedentes de nuestros actuales “planes” de conservación.

48 CFR 15.307 - Proposal revisions.

Science.gov (United States)

2010-10-01

... AND CONTRACT TYPES CONTRACTING BY NEGOTIATION Source Selection 15.307 Proposal revisions. (a) If an... allow proposal revisions to clarify and document understandings reached during negotiations. At the... submit a final proposal revision. The contracting officer is required to establish a common cut-off date...

7 CFR 3015.115 - Budget revisions.

Science.gov (United States)

2010-01-01

... 7 Agriculture 15 2010-01-01 2010-01-01 false Budget revisions. 3015.115 Section 3015.115..., DEPARTMENT OF AGRICULTURE UNIFORM FEDERAL ASSISTANCE REGULATIONS Programmatic Changes and Budget Revisions § 3015.115 Budget revisions. (a) Nonconstruction projects. (1) Except as provided in paragraph (a)(2) of...

Sobre los saberes culturales y el fenómeno "sentirse bien-sentirse mal" On cultural knowledge and the phenomenon "feel good-fell bad"

OpenAIRE

Virtudes Rodero Sánchez; Carme Vives Relats; Sagrario Acebedo Urdiales; Carme Ferré Grau

2010-01-01

El objetivo del presente estudio es identificar los saberes culturales inmersos en el fenómeno "sentirse-bien, sentirse mal", en diferentes situaciones de cuidado. Se elaboró un estudio cualitativo con un enfoque fenomenológico interpretativo, mediante el análisis de 18 narrativas a partir de entrevistas en profundidad realizadas por alumnas del Máster en Ciencias de la Enfermería en diferentes contextos de cuidados. Las categorías identificadas fueron: (1) Cronicidad y concepto de sentirse b...

A study on scar revision

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Ashutosh Talwar

2016-04-01

Full Text Available Introduction: Scars are psychologically distressing for the patients and have an impact on the quality of life and self esteem of the patients. Scar revision is an aesthetic skill which is mastered by plastic surgeons and encroached now by dermatosurgeons. Scars on the face are aesthetically unacceptable and various techniques have been improvised for making a scar aesthetically acceptable. Various types of techniques are used for scar revision like W plasty, Z plasty and VY plasty. Aims: To see the efficacy of various scar revision techniques including Z plasty, VY plasty and W plasty in 30 patients with disfiguring scars. Methods: We selected twenty patients of disfiguring scars for the study. The scars from various causes including trauma and burns were included in our study. Various techniques of scar revision include Z plasty, W plasty and VY plasty were performed according to the type and site of scar. Results: Male: female was 1.5: 1. The scar revision surgery yielded excellent results with minimal complications including haematoma formation, secondary infection and delayed healing seen in 5% patients each. Regarding the efficacy of scar revision, excellent improvement was seen in 60% patients, moderate improvement was seen in 30% patients and mild improvement was seen in 10% patients. Conclusions: Dermatologists can employ a number of surgical scar revision techniques. While some are better suited to treat specific types of scars, they can be used in combination with each other or with adjunctive therapies to achieve optimal results.

Staying Home While Studying Abroad: Anti-Imperial Praxis for Globalizing Feminist Visions

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Shireen Roshanravan

2012-05-01

Full Text Available This paper hinges on the recognition that when study-abroad opportunities are presented and perceived as a means of access to global perspectives on women and gender, they reduce the problem of US-centrism in Women's Studies to a geographic rather than an epistemic limitation. According to this logic, physical travel away from the United States can serve as an effective method for overcoming US-centrism and attending to the "global," a curricular strategy that Chandra Mohanty and M. Jacqui Alexander call "the cartographic rule of the transnational as always 'elsewhere'" (Mohanty and Alexander 2010, 33. This cartographic rule reinforces hegemonic representations of the United States as a unified "modern" white/Anglo nation against which the culturally Other terrain of the "global" becomes understandable. As such, the study-abroad approach to internationalizing US Women's Studies relies on the re-erasure of US Women of Color genealogies and epistemologies that disrupt the white/Anglo cultural assumptions grounding the field's central category of "woman/women." If challenging US-centrism in US Women's Studies is meant to dismantle the white/Anglo monocultural perspective of US imperialism, I argue that the geographic travel imperative of "study abroad" must be tempered by a re-inhabitation of the field through the radical genealogies and epistemologies of US Women of Color, a strategy I call the anti-imperial feminist praxis of "staying home."

Elementos de la praxis y del corpus del conocimiento etnoecológico tseltal en comunidades de la Sierra Norte de Chiapas

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José Ramón Rodríguez Moreno

2014-01-01

Full Text Available Las estrategias de uso y manejo de los ecosistemas como las que practican los tseltales en la Sierra Norte de Chiapas han sido insistentemente descritas por una visión occidental “científica” como sistemas de baja productividad y derrochadoras de recursos naturales. En este estudio se reseñan algunos aspectos del cosmos, corpus y praxis del conocimiento que se posee en comunidades tseltales, a partir del hilo conductor de un rubro específico del campo mexicano, el maíz, y de otras manifestaciones del conocimiento local, que permiten desmontar la marginación del sistema de conocimiento local con que lo ha revestido la visión occidental.

Ventriculoperitoneal shunt complications needing shunt revision in children: A review of 5 years of experience with 48 revisions

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Rajendra K Ghritlaharey

2012-01-01

Full Text Available Background: The aim of this study was to review the management of ventriculoperitoneal (VP shunt complications in children. Patients and Methods: During the last 5 years (January 1, 2006 to December 31, 2010, 236 VP shunt operations were performed in children under 12 years of age; of these, 40 (16.94% developed shunt complications and those who underwent VP shunt revisions were studied. Results: This prospective study included 40 (28 boys and 12 girls children and required 48 shunt revisions. Complications following VP shunts that required shunt revisions were peritoneal catheter/peritoneal end malfunction (18, shunt/shunt tract infections (7, extrusion of peritoneal catheter through anus (5, ventricular catheter malfunction (4, cerebrospinal fluid (CSF leak from abdominal wound (4, shunt system failure (2, ventricular end/shunt displacement (2, CSF pseudocysts peritoneal cavity (2, extrusion of peritoneal catheter from neck, chest, abdominal scar and through umbilicus, one each. Four-fifth of these shunt complications occurred within 6 months of previous surgery. Surgical procedures done during shunt revisions in order of frequency were revision of peritoneal part of shunt (27, 56.25%, revision of entire shunt system (6, 12.5%, extra ventricular drainage and delayed re-shunt (5, 10.41%, shunt removal and delayed re-shunt (5, 10.41%, opposite side shunting (2, 4.16%, cysts excision and revision of peritoneal catheter (2, 4.16% and revision of ventricular catheter (1, 2.08%. The mortalities following VP shunt operations were 44 (18.64% and following shunt revisions were 4 (10%. Conclusions: VP shunt done for hydrocephalus in children is not only prone for complications and need for revision surgery but also associated with considerable mortality.

Malária no Brasil: panorama epidemiológico na última década

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Barata Rita de Cássia B.

1995-01-01

Full Text Available Este artigo apresenta, de maneira resumida, as principais alterações que marcaram a ocorrência de malária, no Brasil, nesta última década. Chama-se a atenção para o processo de focalização da doença, com a concentração da transmissão em áreas, relativamente restritas, da região amazônica. A mudança na situação epidemiológica acarreta a revisãoconceitual, levando ao abandono da concepção de "doença de massa" e à elaboração da teoria focal. Do mesmo modo, as ações de controle sofrem os impactos das transformações ocorridas e as tentativas de erradicação são abandonadas e substituídas por medidas de controle diversificadas e adaptadas a cada localidade. As novas propostas, oriundas da Conferência Ministerial de Amsterdam, são apresentadas e comentadas.

Praxis induction. Definition, relation to epilepsy syndromes, nosological and prognostic significance. A focused review.

Science.gov (United States)

Yacubian, Elza Márcia; Wolf, Peter

2014-04-01

There is increasing awareness that reflex epileptic mechanisms provide unique insight into ictogenesis in human epilepsies. Several of the described triggers have in common that they imply complex visuomotor coordination and decision-making; they are today regarded as variations of one principle, i.e. praxis induction (PI). This focused review considers PI from the aspects of history and delineation, clinical and electroencephalographic presentation, syndromatic relations, prevalence, mechanisms of ictogenesis and nosological implications, treatment and prognosis. We reviewed a series of published articles and case reports on PI in order to clarify clinical and electroencephalographic findings, treatment and outcome. Findings of both induction and inhibition by the same stimuli suggest widening the reflex epilepsy concept into a broader one of epilepsies with exogenous modification of ictogenesis. PI is closely related to juvenile myoclonic epilepsy (JME) where hyperexcitability and hyperconnectivity of the entire network of visuomotor coordination seem to provide the precondition for eliciting reflex myocloni in the musculature active in the precipitating task. The conclusions on ictogenesis derived from PI support the concept of JME as a system disorder of the brain. Copyright © 2014 British Epilepsy Association. Published by Elsevier Ltd. All rights reserved.

Simulação no contexto de problemas mal estruturados

Directory of Open Access Journals (Sweden)

Antônio Sérgio de Souza

1994-12-01

Full Text Available Simulação é atualmente reconhecida como uma poderosa ferramenta no projeto, análise e operação de sistemas produtivos. Apesar dos avanços recentes em linguagens de simulação, interfaces gráficas e geradores de aplicações, simulação ainda é uma técnica cara e pouco eficiente. Discute-se no texto algumas causas deste fato no contexto de problemas mal estruturados, como é o caso de planejamento e controle da produção. Discute-se a necessidade de realização da modelagem conceitual, não apenas como um passo estanque no processo de simulação, mas de forma progressiva e dinâmica, durante todo o ciclo de vida do projeto, servindo como uma interface entre os contextos real e de simulação.Simulation is now recognized as powerful tool in project, analyses and operation of produtive systems. Although the recent advances in simulation languages, graphical interfaces and in generating applications, simulation is still an expensive and not so efficient technique. In this text we dicuss some reasons for this in the context of not well strutured problems, asit is the case of production planning and control. It is also dicussed the necessity of developing the conceptual modeling of the real system, not only as a separated step in the simulation process, but in a progressive and dynamic way, during the project's life cycle as an interface between the real system and simulation.

Decodificando la esencia del mal, o del terror a la muerte del hijo

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Maximiliano Korstanje

2011-01-01

Full Text Available Durante muchos años filósofos y teólogos se han cuestionado sobre la cuestión de la caída. Es innumerable la bibliografía sobre el tema como así también las propias dudas sobre la omnipresencia y sabiduría de un Dios que implícitamente o no permite la presencia del pecado por medio de su propia creación. El mito fundador de querubín Lucifer no sólo simboliza la relación entre el hombre y la traición sino también el amor filial entre el padre y su creación las cuales concilian la negación cultural de la muerte de la progenie o generaciones más jóvenes. Utilizando la teoría antropológica de los dones de M. Mauss, el presente trabajo teórico intentará explicar el origen mítico del mal dentro de la tradición judeo-cristiana como una de las elaboraciones más temidas, la muerte del hijo.

Cochlear implant revision surgeries in children.

Science.gov (United States)

Amaral, Maria Stella Arantes do; Reis, Ana Cláudia Mirândola B; Massuda, Eduardo T; Hyppolito, Miguel Angelo

2018-02-16

The surgery during which the cochlear implant internal device is implanted is not entirely free of risks and may produce problems that will require revision surgeries. To verify the indications for cochlear implantation revision surgery for the cochlear implant internal device, its effectiveness and its correlation with certain variables related to language and hearing. A retrospective study of patients under 18 years submitted to cochlear implant Surgery from 2004 to 2015 in a public hospital in Brazil. Data collected were: age at the time of implantation, gender, etiology of the hearing loss, audiological and oral language characteristics of each patient before and after Cochlear Implant surgery and any need for surgical revision and the reason for it. Two hundred and sixty-five surgeries were performed in 236 patients. Eight patients received a bilateral cochlear implant and 10 patients required revision surgery. Thirty-two surgeries were necessary for these 10 children (1 bilateral cochlear implant), of which 21 were revision surgeries. In 2 children, cochlear implant removal was necessary, without reimplantation, one with cochlear malformation due to incomplete partition type I and another due to trauma. With respect to the cause for revision surgery, of the 8 children who were successfully reimplanted, four had cochlear calcification following meningitis, one followed trauma, one exhibited a facial nerve malformation, one experienced a failure of the cochlear implant internal device and one revision surgery was necessary because the electrode was twisted. The incidence of the cochlear implant revision surgery was 4.23%. The period following the revision surgeries revealed an improvement in the subject's hearing and language performance, indicating that these surgeries are valid in most cases. Copyright © 2018 Associação Brasileira de Otorrinolaringologia e Cirurgia Cérvico-Facial. Published by Elsevier Editora Ltda. All rights reserved.

Realezas entre o bem e o mal: as representações de monarcas nas páginas da Marvel Comics

OpenAIRE

Guerra, Fábio Vieira

2016-01-01

Este trabalho propõe analisar três das monarquias apresentadas nas narrativas da editora americana de quadrinhos Marvel Comics. Essas histórias têm como protagonistas seres com habilidades extraordinárias chamados de super-heróis. Pautados em uma disputa dualista entre o Bem e o Mal, os quadrinhos de super-heróis são expressão de um imaginário coletivo sobre a nação estadunidense e os valores que norteiam sua organização social e suas ações no mundo. Desse modo, a representação de outros país...

Diagnóstico tardio de malária em área endêmica de dengue na extra-Amazônia Brasileira: experiência recente de uma unidade sentinela no estado do Rio de Janeiro Delayed diagnosis of malaria in a dengue endemic area in the Brazilian extra-Amazon: recent experience of a malaria surveillance unit in state of Rio de Janeiro

Directory of Open Access Journals (Sweden)

Anielle de Pina Costa

2010-10-01

Full Text Available INTRODUÇÃO: A letalidade da malária na região extra-amazônica é cerca de 80 vezes maior do que na Amazônia, que concentra 99,8% dos casos do país. Em áreas de transmissão de dengue, como o Rio de Janeiro, o atraso no diagnóstico e tratamento da malária dos pacientes com febre, provenientes de áreas endêmicas de malária, pode ser, entre outros fatores, devido à confusão entre o diagnóstico das duas doenças pelos generalistas da rede de assistência médica. Neste trabalho, apresentamos as consequências do atraso diagnóstico em três pacientes com malária por Plasmodium falciparum; P. malariae e P. vivax, que, após o périplo habitual para tratamento de dengue, procuraram a nossa instituição onde foram corretamente diagnosticados e submetidos aos tratamentos adequados. MÉTODOS: Descrição de três casos de malária diagnosticada tardiamente e encaminhados ao IPEC/ FIOCRUZ, entre os anos de 2007 e 2008. RESULTADOS: uma brasileira proveniente de Moçambique, primo-infectada por P. falciparum, com malária diagnosticada após 6 dias do início da febre, morreu com malária cerebral e choque. Outro paciente com malária por P. malariae teve um curso grave e prolongado, mas ficou curado após o tratamento específico. A terceira paciente diagnosticada tardiamente apresentou malária por P. vivax adquirida na região de Mata Atlântica no Estado do Rio. CONCLUSÕES: Os profissionais de saúde do Rio devem ser treinados para aperfeiçoar a vigilância e o tratamento oportuno da malária e evitar desfechos mórbidos e fatais. Sugere-se que uma investigação de focos de malária autóctone em áreas de mata no estado seja realizada.INTRODUCTION: The mortality of malaria in the extra-Amazon region is about 80 times higher than in the Amazon region, where malaria is concentrated (99.8% of cases. In areas of dengue transmission, delay in the diagnosis and treatment of malaria in patients with fever who reside in areas of malaria

24 CFR 968.225 - Budget revisions.

Science.gov (United States)

2010-04-01

... 24 Housing and Urban Development 4 2010-04-01 2010-04-01 false Budget revisions. 968.225 Section... Fewer Than 250 Units) § 968.225 Budget revisions. (a) A PHA shall not incur any modernization cost in excess of the total HUD-approved CIAP budget. A PHA shall submit a budget revision, in a form prescribed...

Regresso às origens: pistas para a construção do bem e do mal

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Miguel Ângelo Rodrigues Fernandes

2011-01-01

Full Text Available Nowadays, divisions still impose themselves. One of those divisions has become particularly relevant in contemporary culture. On one side, the Axis of Good. On the other, the Axis of Evil. In between both ends, conflicts for power. That dualism and those conflicts, building blocks of the process of constructing cultural identities, being contemporary, find part of their history in discourses of old, of which Christianity is a part. / Atualmente, as divisões continuam a impor-se. Uma dessas divisões tornou-se particularmente pregnante na cultura contemporânea. De um lado, o Eixo do Bem. Do outro, o Eixo do Mal. Mediando os dois polos, conflitos de poder. Esse dualismo e esses conflitos, constituintes do processo de construção de identidades culturais, ainda que contemporâneos, encontram parte da sua história em discursos antigos, que o Cristianismo integra.

Sobre el control convencional en la praxis penal internacional y doméstica de los Derechos Fundamentales

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Duvi Teixidor

2013-12-01

Full Text Available Se trata de una aproximación a la dogmática penal internacional, en el ámbito interamericano y europeo, con especial énfasis en el paradigma normativo asumido en la praxis de derechos humanos. El enfoque discurre desde el principio transversal de imparcialidad a la justificación y aplicación del Derecho Penal Internacional de Derechos humanos, mediante la adopción del espiral hermenéutico. En este plano analítico relacional, se arriba al examen de la teoría del caso asumida en distintos ejemplos que consolidan una jurisprudencia principialista, para la efectiva realización de los derechos fundamentales aquí y ahora (Dasein. A partir de esa expresión de sentido, se hace hincapié en las fases del control de convencionalidad a nivel jurisdiccional doméstico e internacional.

Intrinsic magnetic properties of Sm2Fe17-xMxNy/Cy (M=Al, Ga or Si)

International Nuclear Information System (INIS)

Kubis, M.; Eckert, D.; Gebel, B.; Mueller, K.-H.; Schultz, L.

2000-01-01

Curie temperature T c , saturation polarization J s and anisotropy field H a of Sm 2 Fe 17-x M x N y /C y with M=Al, Ga or Si (x≤3, y∼3) were determined by thermomagnetic measurements and a numerical fitting procedure of demagnetization curves. An increasing amount of the substitutional element M leads to an increase of T c of the Sm 2 Fe 17-x M x parent compounds and generally to a decrease of T c , J s and H a for the interstitial nitrides and carbides. However, for small M contents, x≤1, an increased H a was observed compared to the substitution-free interstitial compounds. Gas-carburized and melt-carburized Sm 2 Fe 15 Ga 2 C y samples showed large differences in J s and H a but identical T c values

Revised National Pressure Ulcer Advisory Panel Pressure Injury Staging System: Revised Pressure Injury Staging System.

Science.gov (United States)

Edsberg, Laura E; Black, Joyce M; Goldberg, Margaret; McNichol, Laurie; Moore, Lynn; Sieggreen, Mary

Our understanding of pressure injury etiology and development has grown in recent years through research, clinical expertise, and global interdisciplinary expert collaboration. Therefore, the National Pressure Ulcer Advisory Panel (NPUAP) has revised the definition and stages of pressure injury. The revision was undertaken to incorporate the current understanding of the etiology of pressure injuries, as well as to clarify the anatomical features present or absent in each stage of injury. An NPUAP-appointed Task Force reviewed the literature and created drafts of definitions, which were then reviewed by stakeholders and the public, including clinicians, educators, and researchers around the world. Using a consensus-building methodology, these revised definitions were the focus of a multidisciplinary consensus conference held in April 2016. As a result of stakeholder and public input, along with the consensus conference, important changes were made and incorporated into the new staging definitions. The revised staging system uses the term injury instead of ulcer and denotes stages using Arabic numerals rather than Roman numerals. The revised definition of a pressure injury now describes the injuries as usually occurring over a bony prominence or under a medical or other device. The revised definition of a Stage 2 pressure injury seeks to clarify the difference between moisture-associated skin damage and injury caused by pressure and/or shear. The term suspected has been removed from the Deep Tissue Pressure Injury diagnostic label. Each definition now describes the extent of tissue loss present and the anatomical features that may or may not be present in the stage of injury. These important revisions reflect the methodical and collaborative approach used to examine the available evidence and incorporate current interdisciplinary clinical expertise into better defining the important phenomenon of pressure injury etiology and development.

Microcomputers and the Improvement of Revision Skills.

Science.gov (United States)

Balajthy, Ernest; And Others

1987-01-01

Discusses use of word processing software as an effective tool in writing and revision instruction, and describes the role of the teacher. Examples of exercises that encourage revision and of software designed to teach effective revision skills are reviewed. (MBR)

Individual questions of financial control and revision

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В. М. Глібко

2015-05-01

Full Text Available Problem setting. In modern conditions at investigation and gathering of proofs in criminal proceedings according to item 93 CPC of Ukraine collecting of proofs which is carried out by the criminal proceedings parties, victim is important, the representative of the legal person, in which relation carries out manufacture, including a way истребования and receptions from public authorities, local governments, the enterprises, establishments and organisations, official and physical persons of things, documents, data, conclusions of experts, conclusions of revisions and certificates of checks. Recent research and publications analisis. In scientific sources questions of carrying out of revisions S. B.Zhivko, V.V.Akimov, G.Demjanchuk, J.Buzdugan is considered. Paper objective. Article purpose is studying and definition of a place of revision among forms of inspection of the state control and use of results of revision in criminal proceedings. Paper main body. Off-schedule exit revision that is revision which is not provided in plans of work of body of the state financial control is considered and is spent at presence at least one of the circumstances listed in item 11 of the Law of Ukraine «About main principles of realisation of the state financial control in Ukraine». If revision is carried out on request of investigating bodies it is spent on the basis of the petition of the inspector and accepted by the results of consideration of this petition of the decision of the investigatory judge. The primary goal of revision on request of investigating bodies or on the basis of court definition is reception of proofs on business. Therefore the revision certificate admits the written proof as on the basis of its conclusion of the inspector, the public prosecutor receives the information on a perfect crime, abusing, and also on the persons who have committed a crime, on the period of commission of crime and an amount of damage. In criminal

Outcome, revision rate and indication for revision following resurfacing hemiarthroplasty for osteoarthritis of the shoulder

DEFF Research Database (Denmark)

Rasmussen, J V; Polk, A; Sorensen, A K

2014-01-01

In this study, we evaluated patient-reported outcomes, the rate of revision and the indications for revision following resurfacing hemiarthroplasty of the shoulder in patients with osteoarthritis. All patients with osteoarthritis who underwent primary resurfacing hemiarthroplasty and reported...... to the Danish Shoulder Arthroplasty Registry (DSR), between January 2006 and December 2010 were included. There were 772 patients (837 arthroplasties) in the study. The Western Ontario Osteoarthritis of the Shoulder (WOOS) index was used to evaluate patient-reported outcome 12 months (10 to 14) post......-operatively. The rates of revision were calculated from the revisions reported to the DSR up to December 2011 and by checking deaths with the Danish National Register of Persons. A complete questionnaire was returned by 688 patients (82.2%). The mean WOOS was 67 (0 to 100). A total of 63 hemiarthroplasties (7...

Expedited technology demonstration project (Revised mixed waste management facility project) Project baseline revision 4.0 and FY98 plan

International Nuclear Information System (INIS)

Adamson, M. G.

1997-01-01

The re-baseline of the Expedited Technology Demonstration Project (Revised Mixed Waste Facility Project) is designated as Project Baseline Revision 4.0. The last approved baseline was identified as Project Baseline Revision 3.0 and was issued in October 1996. Project Baseline Revision 4.0 does not depart from the formal DOE guidance followed by, and contained in, Revision 3.0. This revised baseline document describes the MSO and Final Forms testing activities that will occur during FY98, the final year of the ETD Project. The cost estimate for work during FY98 continues to be $2.OM as published in Revision 3.0. However, the funds will be all CENRTC rather than the OPEX/CENTRC split previously anticipated. LLNL has waived overhead charges on ETD Project CENRTC funds since the beginning of project activities. By requesting the $2.OM as all CENTRC a more aggressive approach to staffing and testing can be taken. Due to a cost under- run condition during FY97 procurements were made and work was accomplished, with the knowledge of DOE, in the Feed Preparation and Final Forms areas that were not in the scope of Revision 3.0. Feed preparation activities for FY98 have been expanded to include the drum opening station/enclosure previously deleted

Efficacy of tennis elbow (epicondylitis humeri radialis) treatment in CBR "Praxis".

Science.gov (United States)

Pecar, Dzemal; Avdić, Dijana

2009-02-01

Tennis elbow (Epicondylitis humeri radialis) is the most frequent reason that patients with elbow pain report to a physician. The exact cause of elbow pain is still unclear. However, it is certainly causally connected with connective intersection between forearm muscle and bone in the elbow region. In this paper, we analyzed patients that, over the period of 15 years, reported to "Praxis" clinic for elbow pain treatment (Epicondylitis humeri radialis). Of the total number of 228 patients, 126 were male, 101 female while one patient was younger than 14. Initial analysis established that average overall health condition grade was 2,87 at the onset of treatment. Following the treatment completion that grade was 4,48. Of the total number of 223 patients who were treated by combined method of manipulation and local corticosteroid instillation, eight patients received physical therapy as well. Thus, surgical treatment was not necessary in any patient. The patients' treatment included: 1. Application of manipulative methods in order to reestablish mobility in the "blocked" radio-humeral and the upper radio-ulnar joints. 2. Local instillation of corticosteroid depot in order to control inflammation (enthesitis) and thus, eliminate pain and establish physiological conditions for functioning of joint and local structures. Unlike conservative method which includes initial immobilization due to irritation and inflammation development prevention with concomitant analgesic and antirheumatic therapy, initial application of manipulation with reinstatement of joint mobility instead of immobilization with subsequent instillation of steroid preparations achieves functional restitution and fast reinstatement of full working ability, as a rule.

Circumcision revision in male children

Directory of Open Access Journals (Sweden)

Mohammed A. Al-Ghazo

2006-08-01

Full Text Available OBJECTIVE: To determine indications for circumcision revision and to identify the specialty of the person who performed unsatisfactory primary circumcision. MATERIALS AND METHODS: The authors reviewed medical records of 52 cases that underwent circumcision revision over a 6-year period (1998 to 2004. Sleeve surgical technique was used for revision in patients with redundant foreskin or concealed penis, penoplasty for partial or complete degloving of the penis and meatotomy for external meatal stenosis. The mean age of children was 32 months (range 6 months to 9 years. RESULTS: Most of unsatisfactory primary circumcisions (86.7% were performed by laymen. All patients who underwent circumcision revision had good to excellent cosmetic results. CONCLUSION: Primary circumcision performed by laymen carry a high complication rate and serious complications may occur. A period of training and direct supervision by physicians is required before allowing laymen to perform circumcision independently.

The economic impact of revision otologic surgery.

Science.gov (United States)

Nadimi, Sahar; Leonetti, John P; Pontikis, George

2016-03-01

Revision otologic surgery places a significant economic burden on patients and the healthcare system. We conducted a retrospective chart analysis to estimate the economic impact of revision canal-wall-down (CWD) mastoidectomy. We reviewed the medical records of all 189 adults who had undergone CWD mastoidectomy performed by the senior author between June 2006 and August 2011 at Loyola University Medical Center in Maywood, Ill. Institutional charges and collections for all patients were extrapolated to estimate the overall healthcare cost of revision surgery in Illinois and at the national level. Of the 189 CWD mastoidectomies, 89 were primary and 100 were revision procedures. The total charge for the revision cases was $2,783,700, and the net reimbursement (collections) was $846,289 (30.4%). Using Illinois Hospital Association data, we estimated that reimbursement for 387 revision CWD mastoidectomies that had been performed in fiscal year 2011 was nearly $3.3 million. By extrapolating our data to the national level, we estimated that 9,214 patients underwent revision CWD mastoidectomy in the United States during 2011, which cost the national healthcare system roughly $76 million, not including lost wages and productivity. Known causes of failed CWD mastoidectomies that often result in revision surgery include an inadequate meatoplasty, a facial ridge that is too high, residual diseased air cells, and recurrent cholesteatoma. A better understanding of these factors can reduce the need for revision surgery, which could have a positive impact on the economic strain related to this procedure at the local, state, and national levels.

Conflict fields of journalistic praxis in Colombia

Directory of Open Access Journals (Sweden)

Rousbeh Legatis

2010-10-01

Full Text Available The chronic uncertainty for journalists and editors in carrying out their professional work in Colombia has many sources and has been serious for decades. Currently – besides indicators of extreme physical violence (such as daily attacks, abuse, kidnappings and murders – problem areas are strongly marking journalistic work in Colombia that are often neglected in the international discussion, such as inadequate training offerings, unsatisfactory infrastructure in the workplace, precarious wage situations, lack of independence in relationship to editors and a poorly taught understanding of professional ethics. These structural problems produce qualitative deficiencies – especially in conflict reportage. But instead of stagnation, change is occurring. Colombian journalists are revising their self-image, at the same time developing a problem consciousness in their own work, and are actively trying to correct the deficiencies.

Permanent Training of Teachers as a Reference to Educational Quality

Directory of Open Access Journals (Sweden)

Johana Carolina Peña Lozada

2017-08-01

Full Text Available The present article of bibliographical revision intends to make a reflection to characterize the Permanent Formation of the Teachers as Referent of the Educational Quality, through a documentary revision, in order to realize an evaluation of the component permanent formation under the scheme of the educational quality, The analysis points to considerations made by different authors, in the most relevant aspects, it becomes notorious and imperative to include policies, plans and programs according to the ongoing training of the teacher to achieve all the objectives pursued by education in the Different spaces that comprise it involving the praxis of the teacher in its action with a view to a better educational quality.

How to Revise, and Revise Really Well, for Premier Academic Journals

DEFF Research Database (Denmark)

LaPlaca, Peter J.; Lindgreen, Adam; Vanhamme, Joelle

2018-01-01

Most of the premier academic journals in all fields routinely have rejection rates of 80%, 95%, or higher. All journals prefer articles that make significant contributions to the field. Revising a manuscript and responding properly to the comments of reviewers and editors often is challenging....... This article discusses how to revise effectively a manuscript according to the (minor or major) comments of reviewers and editors for premier academic journals. We provide a series of tips for helping the authors in their endeavor, making the process less arduous and improving the possibility of a positive...

A brief history of typical absence seizures - Petit mal revisited.

Science.gov (United States)

Brigo, Francesco; Trinka, Eugen; Lattanzi, Simona; Bragazzi, Nicola Luigi; Nardone, Raffaele; Martini, Mariano

2018-03-01

In this article, we have traced back the history of typical absence seizures, from their initial clinical description to the more recent nosological position. The first description of absence seizures was made by Poupart in 1705 and Tissot in 1770. In 1824, Calmeil introduced the term "absences", and in 1838, Esquirol for the first time used the term petit mal. Reynolds instead used the term "epilepsia mitior" (milder epilepsy) and provided a comprehensive description of absence seizures (1861). In 1854, Delasiauve ranked absences as the seizure type with lower severity and introduced the concept of idiopathic epilepsy. Otto Binswanger (1899) discussed the role of cortex in the pathophysiology of "abortive seizures", whereas William Gowers (1901) emphasized the importance of a detailed clinical history to identify nonmotor seizures or very mild motor phenomena which otherwise may go unnoticed or considered not epileptic. At the beginning of the 20th Century, the term pyknolepsy was introduced, but initially was not universally considered as a type of epilepsy; it was definitely recognized as an epileptic entity only in 1945, based on electroencephalogram (EEG) recordings. Hans Berger, the inventor of the EEG, made also the first EEG recording of an atypical absence (his results were published only in 1933), whereas the characteristic EEG pattern was reported by neurophysiologists of the Harvard Medical School in 1935. The discovery of EEG made it also possible to differentiate absence seizures from so called "psychomotor" seizures occurring in temporal lobe epilepsy. Penfield and Jasper (1938) considered absences as expression of "centrencephalic epilepsy". Typical absences seizures are now classified by the International League Against Epilepsy among generalized nonmotor (absence) seizures. Copyright © 2018 Elsevier Inc. All rights reserved.

A taxonomic revision of the genus Podocarpus

NARCIS (Netherlands)

Laubenfels, de D.J.

1985-01-01

In connection with the forthcoming revision of the Coniferae for the Flora Malesiana, the author thought it necessary to revise the genus Podocarpus. Although this genus has a substantial representation in Malesia (30 species), the revision is too involved to be appropriate with the Flora Malesiana

Nevada Test Site Radiological Control Manual. Revision 1

Energy Technology Data Exchange (ETDEWEB)

None, None

2010-02-09

This document supersedes DOE/NV/25946--801, “Nevada Test Site Radiological Control Manual,” Revision 0 issued in October 2009. Brief Description of Revision: A minor revision to correct oversights made during revision to incorporate the 10 CFR 835 Update; and for use as a reference document for Tenant Organization Radiological Protection Programs.

[An overview on the collation and revision of medical books by the Bureau for Revising Medical Books in the Northern Song Dynasty].

Science.gov (United States)

Meng, Yongliang; Liang, Yongxuan

2014-07-01

The Bureau for Revising Medical Books was a temporary agency established by the government of the Northern Song Dynasty in 1057, the 2nd year of Jiayou of Emperor Renzong, exclusively for the edition, revision and publishing of ancient medical books. 11 medical books were revised and edited by 13 Bureau members in a period of 12 years until 1069, the 2nd year of Xining of Emperor ShenZong, which eventually became the final versions until today. 8 medical books were initially planned for the revision, but 11 were actually completed in the end. The time for completing a revision varied from over 10 years at most to less than 1 year at least. Instead of working in the office, the officers of the Bureau for Revising Medical Books did their works at home. The members of the said Bureau came from the Tiju officer of the Bureau for Revising Medical Books and the officials of revising medical books, consisting of both Confucian ministers and medical officers. Confucian ministers played an important role in revising medical books. The Bureau had a strict workflow in electing revising officials, making the project, and the determination of the principles and arrangements of the tasks of editing and proofreading.

Molecular characterization of multivalent bioconjugates by size-exclusion chromatography (SEC) with multi-angle laser light scattering (MALS)

Science.gov (United States)

Pollock, Jacob F.; Ashton, Randolph S.; Rode, Nikhil A.; Schaffer, David V.; Healy, Kevin E.

2013-01-01

The degree of substitution and valency of bioconjugate reaction products are often poorly judged or require multiple time- and product- consuming chemical characterization methods. These aspects become critical when analyzing and optimizing the potency of costly polyvalent bioactive conjugates. In this study, size-exclusion chromatography with multi-angle laser light scattering was paired with refractive index detection and ultraviolet spectroscopy (SEC-MALS-RI-UV) to characterize the reaction efficiency, degree of substitution, and valency of the products of conjugation of either peptides or proteins to a biopolymer scaffold, i.e., hyaluronic acid (HyA). Molecular characterization was more complete compared to estimates from a protein quantification assay, and exploitation of this method led to more accurate deduction of the molecular structures of polymer bioconjugates. Information obtained using this technique can improve macromolecular engineering design principles and better understand multivalent macromolecular interactions in biological systems. PMID:22794081

Emotion Processes in Knowledge Revision

Science.gov (United States)

Trevors, Gregory J.; Kendeou, Panayiota; Butterfuss, Reese

2017-01-01

In recent years, a number of insights have been gained into the cognitive processes that explain how individuals overcome misconceptions and revise their previously acquired incorrect knowledge. The current study complements this line of research by investigating the moment-by-moment emotion processes that occur during knowledge revision using a…

75 FR 57597 - Revised Proposal for Revisions to the Schedules of Civil Penalties for a Violation of a Federal...

Science.gov (United States)

2010-09-21

... Revisions to the Schedules of Civil Penalties for a Violation of a Federal Railroad Safety Law or Federal... railroad safety laws and regulations are necessary because many of FRA's civil penalties have not been..., et al. Revised Proposal for Revisions to the Schedules of Civil Penalties for a Violation of a...

Comprometimento pulmonar na malária (revisão Pulmonary involvement in malaria

Directory of Open Access Journals (Sweden)

Marcos Boulos

1993-02-01

Full Text Available Com uma incidência de 3 a 10% dos casos e letalidade próxima a 70%, o comprometimento pulmonar constitui uma das manifestações mais graves da malária por Plasmodium falciparum. Embora sua patogênese não esteja perfeitamente esclarecida, reconhece-se que a hiperativação do sistema imune por antígenos liberados pelo Plasmodium falciparum desempenhe um importante papel no desencadeamento e agravamento das lesões. A estrutura alvo parece ser o endotélio capilar, responsável pelo fluxo de líquidos para o espaço intersticial. Essas células são ativadas por ação de citocinas, produzidas por linfócitos e macrófagos durante a resposta imune, e passam a expressar em sua membrana celular receptores e moléculas de aderência que facilitam a sequestração de eritrócitos parasitados e também a aderência de células capazes de produzir mediadores inflamatórios. A reação inflamatória e a lesão endotelial que se seguem, juntamente com as alterações hemodinâmicas induzidas pelo bloqueio capilar devido ao acúmulo local de eritrócitos e células inflamatórias causam alterações de permeabilidade vascular e, consequentemente, acúmulo de líquido nos espaços intersticiais e alvéolos. Nos casos mais graves, as manifestações clínicas assemelham-se às do quadro da Síndrome do desconforto respiratório do adulto. Comprometimento pulmonar grave pode se instalar rapidamente em qualquer estágio da evolução clínica da malária, mesmo após a cura parasitológica, desconhecendo-se os fatores desencadeantes. Hiperparasitismo, insuficiência renal e gravidez constituem fatores predisponentes. O prognóstico dependerá da rapidez com que o diagnóstico for estabelecido e o correto tratamento instituído. Além do tratamento instituído contra o parasita, especial atenção deverá ser dispensada à monitorização hemodinâmica, se possível através de cateter de Swan-Ganz, à manutenção de adequada oxigenação e balanço h

Student-initiated revision in child health.

Science.gov (United States)

Alfaham, M; Gray, O P; Davies, D P

1994-03-01

Most teaching of child health in Cardiff takes place in block attachments of 8 weeks. There is an introductory seminar of 2 days followed by a 6-week clinical attachment in a district general hospital in Wales, and then a revision period of one week designed to help students formalize and structure their basic knowledge and to clarify aspects of child health which they may have had difficulty in understanding. The revision programme has to take into account: the short time available, the small number of teaching staff, the most relevant basic knowledge and active participation by the student. This paper describes how this week has been improved through the use of student-initiated revision (SIR). The students' appraisal of this revision and in particular SIR is presented.

Revised licensee event report system

International Nuclear Information System (INIS)

Mays, G.T.; Poore, W.P.

1985-01-01

Licensee Event Reports (LERs) provide the basis for evaluating and assessing operating experience information from nuclear power plants. The reporting requirements for submitting LERs to the Nuclear Regulatory Commission have been revised. Effective Jan. 1, 1984, all events were to be submitted in accordance with 10 CFR 50.73 of the Code of Federal Regulations. Report NUREG-1022, Licensee Event Report System-Description of System and Guidelines for Reporting, describes the guidelines on reportability of events. This article summarizes the reporting requirements as presented in NUREG-1022, high-lights differences in data reported between the revised and previous LER systems, and presents results from a preliminary assessment of LERs submitted under the revised LER reporting system

Clinical and Economic Burden of Revision Knee Arthroplasty

Directory of Open Access Journals (Sweden)

Mohit Bhandari

2012-01-01

Full Text Available Surgery is indicated for symptomatic knee osteoarthritis (OA when conservative measures are unsuccessful. High tibial osteotomy (HTO, unicompartmental knee arthroplasty (UKA, and total knee arthroplasty (TKA are surgical options intended to relieve knee OA pain and dysfunction. The choice of surgical intervention is dependent on several factors such as disease location, patient age, comorbidities, and activity levels. Regardless of surgical treatment, complications such as infection, loosening or lysis, periprosthetic fracture, and postoperative pain are known risks and are indications for revision surgery. The clinical and economic implications for revision surgery are underappreciated. Over 55,000 revision surgeries were performed in 2010 in the US, with 48% of these revisions in patients under 65 years. Total costs associated with each revision TKA surgery have been estimated to be in excess of $49,000. The current annual economic burden of revision knee OA surgery is $2.7 billion for hospital charges alone. By 2030, assuming a 5-fold increase in the number of revision procedures, this economic burden will exceed $13 billion annually. It is appealing to envision a therapy that could delay or obviate the need for arthroplasty. From an actuarial standpoint, this would have the theoretical downstream effect of substantially reducing the number of revision procedures. Although no known therapies currently meet these criteria, such a breakthrough would have a tremendous impact in lessening the clinical and economic burden of knee OA revision surgery.

Humeral windows in revision total elbow arthroplasty.

Science.gov (United States)

Peach, Chris A; Salama, Amir; Stanley, David

2016-04-01

The use of cortical windows for revision elbow arthroplasty has not previously been widely reported. Their use aids safe revision of a well fixed humeral prosthesis and can be used in the setting of dislocation, periprosthetic fracture or aseptic loosening of the ulnar component. We describe our technique and results of cortical windows in the distal humerus for revision elbow arthroplasty surgery.

Diet History Questionnaire: Database Revision History

Science.gov (United States)

The following details all additions and revisions made to the DHQ nutrient and food database. This revision history is provided as a reference for investigators who may have performed analyses with a previous release of the database.

Metabolic and functional connectivity changes in mal de debarquement syndrome.

Directory of Open Access Journals (Sweden)

Yoon-Hee Cha

Full Text Available Individuals with mal de debarquement syndrome (MdDS experience a chronic illusion of self-motion triggered by prolonged exposure to passive motion, such as from sea or air travel. The experience is one of rocking dizziness similar to when the individual was originally on the motion trigger such as a boat or airplane. MdDS represents a prolonged version of a normal phenomenon familiar to most individuals but which persists for months or years in others. It represents a natural example of the neuroplasticity of motion adaptation. However, the localization of where that motion adaptation occurs is unknown. Our goal was to localize metabolic and functional connectivity changes associated with persistent MdDS.Twenty subjects with MdDS lasting a median duration of 17.5 months were compared to 20 normal controls with (18F FDG PET and resting state fMRI. Resting state metabolism and functional connectivity were calculated using age, grey matter volume, and mood and anxiety scores as nuisance covariates.MdDS subjects showed increased metabolism in the left entorhinal cortex and amygdala (z>3.3. Areas of relative hypometabolism included the left superior medial gyrus, left middle frontal gyrus, right amygdala, right insula, and clusters in the left superior, middle, and inferior temporal gyri. MdDS subjects showed increased connectivity between the entorhinal cortex/amygdala cluster and posterior visual and vestibular processing areas including middle temporal gyrus, motion sensitive area MT/V5, superior parietal lobule, and primary visual cortex, while showing decreased connectivity to multiple prefrontal areas.These data show an association between resting state metabolic activity and functional connectivity between the entorhinal cortex and amygdala in a human disorder of abnormal motion perception. We propose a model for how these biological substrates can allow a limited period of motion exposure to lead to chronic perceptions of self-motion.

Revision surgery for failed thermal capsulorrhaphy.

Science.gov (United States)

Park, Hyung Bin; Yokota, Atsushi; Gill, Harpreet S; El Rassi, George; McFarland, Edward G

2005-09-01

With the failure of thermal capsulorrhaphy for shoulder instability, there have been concerns with capsular thinning and capsular necrosis affecting revision surgery. To report the findings at revision surgery for failed thermal capsulorrhaphy and to evaluate the technical effects on subsequent revision capsular plication. Case series; Level of evidence, 4. Fourteen patients underwent arthroscopic evaluation and open reconstruction for a failed thermal capsulorrhaphy. The cause of the failure, the quality of the capsule, and the ability to suture the capsule were recorded. The patients were evaluated at follow-up for failure, which was defined as recurrent subluxations or dislocations. The origin of the instability was traumatic (n = 6) or atraumatic (n = 8). At revision surgery in the traumatic group, 4 patients sustained failure of the Bankart repair with capsular laxity, and the others experienced capsular laxity alone. In the atraumatic group, all patients experienced capsular laxity as the cause of failure. Of the 14 patients, the capsule quality was judged to be thin in 5 patients and ablated in 1 patient. A glenoid-based capsular shift could be accomplished in all 14 patients. At follow-up (mean, 35.4 months; range, 22 to 48 months), 1 patient underwent revision surgery and 1 patient had a subluxation, resulting in a failure rate of 14%. Recurrent capsular laxity after failed thermal capsular shrinkage is common and frequently associated with capsular thinning. In most instances, the capsule quality does not appear to technically affect the revision procedure.

Opava (K. Ú. Kateřinky, Malé Hoštice, okres Opava). " Na hoštických lukách". Doba laténská. Sídliště. Záchranný výzkum.

Czech Academy of Sciences Publication Activity Database

Juchelka, Jiří

2009-01-01

Roč. 50, 1-2 (2009), s. 312 ISSN 1211-7250 Institutional research plan: CEZ:AV0Z80010507 Keywords : Czech Silesia * Malé Hoštice * Latén Cultur e Subject RIV: AC - Archeology, Anthropology, Ethnology

Introductory Business Textbook Revision Cycles: Are They Getting Shorter?

Science.gov (United States)

Zinser, Brian; Brunswick, Gary

2010-01-01

The rate of textbook revision cycles is examined in light of the recent trend towards more rapid revisions (and adoptions of textbooks). The authors conduct background research to better understand the context for textbook revision cycles and the environmental forces that have been influencing what appears to be more rapid textbook revisions. A…

Revised Rules for Concrete Bridges

DEFF Research Database (Denmark)

Thoft-Christensen, Palle; Jensen, F. M.; Middleton, C.

This paper is based on research performed for the Highway Agency, London, UK under the project DPU/9/44 "Revision of Bridge Assessment Rules Based on Whole Life Performance: Concrete Bridges" It contains details of a methodology which can be used to generate Whole Life (WL) reliability profiles....... These WL reliability profiles may be used to establish revised rules for Concrete Bridges....

Inferential revision in narrative texts: An ERP study.

Science.gov (United States)

Pérez, Ana; Cain, Kate; Castellanos, María C; Bajo, Teresa

2015-11-01

We evaluated the process of inferential revision during text comprehension in adults. Participants with high or low working memory read short texts, in which the introduction supported two plausible concepts (e.g., 'guitar/violin'), although one was more probable ('guitar'). There were three possible continuations: a neutral sentence, which did not refer back to either concept; a no-revise sentence, which referred to a general property consistent with either concept (e.g., '…beautiful curved body'); and a revise sentence, which referred to a property that was consistent with only the less likely concept (e.g., '…matching bow'). Readers took longer to read the sentence in the revise condition, indicating that they were able to evaluate their comprehension and detect a mismatch. In a final sentence, a target noun referred to the alternative concept supported in the revise condition (e.g., 'violin'). ERPs indicated that both working memory groups were able to evaluate their comprehension of the text (P3a), but only high working memory readers were able to revise their initial incorrect interpretation (P3b) and integrate the new information (N400) when reading the revise sentence. Low working memory readers had difficulties inhibiting the no-longer-relevant interpretation and thus failed to revise their situation model, and they experienced problems integrating semantically related information into an accurate memory representation.

Programme for the Environmental Control at the Swedish Nuclear Facilities, Revision; Omgivningskontrollprogram foer de kaerntekniska anlaeggningarna, revision

Energy Technology Data Exchange (ETDEWEB)

Linden, Ann-Marie

2004-12-01

This report contains a revised version of the Environmental Monitoring Programme for the Swedish Nuclear Facilities. The revision is based on earlier experiences and evaluations. Some samples have been excluded. Some have been added, for example spruce cone and the food products apple and currant. The sediment samples of 2 cm length have been completed with samples of 10 cm length every fourth year to follow the migration of radio nuclides down the sediment layers over time. The revised Environmental Monitoring Programme is valid from the 1st of January 2005.

“Revising Nabokov Revising”

Directory of Open Access Journals (Sweden)

Marie Bouchet

2010-10-01

Full Text Available Nabokov revised his works as he translated them and, on another plane, canon revisionism has been having its backlash and provoked other refracting waves. The purpose of the conference was to advance Nabokov studies through the discussion of how our view of Nabokov’s standing and his works today should be revised, especially after the publication of The Original of Laura. However the conference was not confined to just this theme, since “revising” is a word rich with implications. To borrow s...

Revision of failed shoulder hemiarthroplasty to reverse total arthroplasty: analysis of 157 revision implants.

Science.gov (United States)

Merolla, Giovanni; Wagner, Eric; Sperling, John W; Paladini, Paolo; Fabbri, Elisabetta; Porcellini, Giuseppe

2018-01-01

There remains a paucity of studies examining the conversion of failed hemiarthroplasty (HA) to reverse total shoulder arthroplasty (RTSA). Therefore, the purpose of this study was to examine a large series of revision HA to RTSA. A population of 157 patients who underwent conversion of a failed HA to a revision RTSA from 2006 through 2014 were included. The mean follow-up was 49 months (range, 24-121 months). The indications for revision surgery included instability with rotator cuff insufficiency (n = 127) and glenoid wear (n = 30); instability and glenoid wear were associated in 38 cases. Eight patients with infection underwent 2-stage reimplantation. Patients experienced significant improvements in their preoperative to postoperative pain and shoulder range of motion (P surgeries, secondary to glenoid component loosening (n = 3), instability (n = 3), humeral component disassembly (n = 2), humeral stem loosening (n = 1), and infection (n = 2). Implant survivorship was 95.5% at 2 years and 93.3% at 5 years. There were 4 reoperations including axillary nerve neurolysis (n = 2), heterotopic ossification removal (n = 1), and hardware removal for rupture of the metal cerclage for an acromial fracture (n = 1). At final follow-up, there were 5 "at-risk" glenoid components. Patients experience satisfactory pain relief and recovery of reasonable shoulder function after revision RTSA from a failed HA. There was a relatively low revision rate, with glenoid loosening and instability being the most common causes. Copyright © 2017 Journal of Shoulder and Elbow Surgery Board of Trustees. Published by Elsevier Inc. All rights reserved.

Revision of the DELFIC Particle Activity Module

Energy Technology Data Exchange (ETDEWEB)

Hooper, David A [ORNL; Jodoin, Vincent J [ORNL

2010-09-01

The Defense Land Fallout Interpretive Code (DELFIC) was originally released in 1968 as a tool for modeling fallout patterns and for predicting exposure rates. Despite the continual advancement of knowledge of fission yields, decay behavior of fission products, and biological dosimetry, the decay data and logic of DELFIC have remained mostly unchanged since inception. Additionally, previous code revisions caused a loss of conservation of radioactive nuclides. In this report, a new revision of the decay database and the Particle Activity Module is introduced and explained. The database upgrades discussed are replacement of the fission yields with ENDF/B-VII data as formatted in the Oak Ridge Isotope Generation (ORIGEN) code, revised decay constants, revised exposure rate multipliers, revised decay modes and branching ratios, and revised boiling point data. Included decay logic upgrades represent a correction of a flaw in the treatment of the fission yields, extension of the logic to include more complex decay modes, conservation of nuclides (including stable nuclides) at all times, and conversion of key variables to double precision for nuclide conservation. Finally, recommended future work is discussed with an emphasis on completion of the overall radiation physics upgrade, particularly for dosimetry, induced activity, decay of the actinides, and fractionation.

Instrumentação anterior da coluna em espondilite tuberculosa mal de pott: Relato de caso

Directory of Open Access Journals (Sweden)

Farage Luciano

2002-01-01

Full Text Available Relatamos caso de tratamento cirúrgico com instrumentação anterior em espondilite tuberculosa (mal de Pott, em mulher de 71 anos, que se encontrava em tratamento para tuberculose na forma pulmonar e evoluiu com dor lombar, dificuldade progressiva para deambular, cifose e disfunção vesical. A ressonância magnética revelou lesão nos corpos vertebrais de T12 e L1 com abcesso paravertebral. A paciente foi tratada cirurgicamente por acesso tóraco-abdominal lateral. Os corpos vertebrais foram ressecados, foi instalado uma gaiola vertical (mesh cage e a coluna foi estabilizada com placa lateral (Z plate e parafusos fixados em T11 e L2. Essa técnica permite boa artrodese dos corpos vertebrais remanescentes e boa estabilidade da coluna, sem comprometer a eficácia dos tuberculostáticos. A paciente foi avaliada um ano após a operação e não apresentava déficit motor, dor residual e a cifose foi desfeita.

Teoría estética, telos del arte y ley formal en Oteiza. Tentativas teóricas y praxis vanguardistas en el contexto de la modernidad

OpenAIRE

Golvano Gutiérrez, Fernando

2018-01-01

426 p. Esta tesis indaga en la génesis y desarrollo de la teoría estética de Oteiza (1908-2003), que la concibe como una interciencia que imbrica intuiciones y postulados metafísicos y existencialistas con otros de signo experimental y racionalista. Examinamos la singularidad de su enfoque, su énfasis normativo y las analogías que establece entre su propósito experimental, que guía su praxis escultórica orientada a la conclusión y final del arte, y sus especulaciones teóricas. Se aborda un...

Integrating Relational Reasoning and Knowledge Revision during Reading

Science.gov (United States)

Kendeou, Panayiota; Butterfuss, Reese; Van Boekel, Martin; O'Brien, Edward J.

2017-01-01

Our goal in this theoretical contribution is to connect research on knowledge revision and relational reasoning. To achieve this goal, first, we review the "knowledge revision components framework" (KReC) that provides an account of knowledge revision processes, specifically as they unfold during reading of texts. Second, we review a…

Comparison of measles complications in well nourished and mal-nourished children

International Nuclear Information System (INIS)

Qaisar, I.; Ahmad, A.; Ahmad, A.

2009-01-01

Measles is the most common and the most infectious of the viral infections of childhood. It can cause severe pneumonia, diarrhoea, encephalitis, and death. A significant proportion of deaths due to measles in young children worldwide are attributable to low weight for age. To compare the measles complications in well-nourished and mal-nourished children, this cross-sectional study was conducted at Paediatric out-patient department and paediatric unit 1 Bahawal Victoria Hospital Bahawalpur. Total 120 patients were included in the study. All patients presented with signs and symptoms suggestive of measles according to WHO criteria. These patients were divided into well nourished and malnourished according to the modified Gomez classification. Both groups were evaluated for measles complications like pneumonia, diarrhoea, encephalitis, corneal ulceration, thrombocytopenia, otitis media and myocarditis by detailed history and complete physical examination, and statistically analysed. In the studied patients, 75 were males and 45 were females. Mean age was 23 months. Fifty-nine (49.2%) patients were well-nourished and 61 (50.8%) were undernourished. Fifty-two (43.3%) patients were having pneumonia. Fifty-three (44.2%) patients were having diarrhoea. Twenty-six (21.7%) patients were having encephalitis. Corneal ulceration was found in 9 (7.5%) patients. Thrombocytopenia and otitis media was present in 1 patient in each group. Fourteen patients expired. Measles is a global epidemic problem having many serious complications, including pneumonia, diarrhoea, encephalitis, corneal ulcerations etc. Moreover these complications are more frequent in under nourished children. Efforts should be made to improve the nutritional status of the children and to eradicate this disease by effective vaccination. (author)

(Mal)nutrition and the new epidemiological trend in a context of development and inequalities.

Science.gov (United States)

Souza, Nathália Paula de; Lira, Pedro Israel Cabral de; Fontbonne, Annick; Pinto, Fernanda Cristina de Lima; Cesse, Eduarda Ângela Pessoa

2017-07-01

The current context of intense social, economic and political transformations has contributed to changes in the health profile of the population and generated discussions about the impact of these changes on the reorganization of society. At the present moment, the increase in non-communicable illnesses and diseases raises major concerns about the paradox of malnutrition and obesity. Based on an in-depth reading and interpretation of texts, documents and databases, this article discusses issues related to nutrition, considering the dimensions of shortages and excesses, the evolution of nutrition over time, and the connection with the new epidemiological trend. We begin with a conceptual characterization, the historical background and the anthropological connections with the guiding theme of the article. We then describe the prevalence, distribution and secular trend of malnutrition and obesity, as well as the temporal relationship with the new epidemiological trend in Brazil within a context of development and inequalities. Finally, we reflect on the issue of (mal)nutrition in post-modernity, the new interests at stake in the health-disease process, as well as international experiences and strategies of partnerships designed to overcome these problems. We conclude by discussing some current advances and challenges in relation to the complexity and speed of contemporary changes.

EPRI BWR Water Chemistry Guidelines Revision

International Nuclear Information System (INIS)

Garcia, Susan E.; Giannelli, Joseph F.

2014-01-01

BWRVIP-190: BWR Water Chemistry Guidelines – 2008 Revision has been revised. The revision committee consisted of U.S. and non-U.S. utilities (members of the BWR Vessel and Internals Protection (BWRVIP) Mitigation Committee), reactor system manufacturers, fuel suppliers, and EPRI and industry experts. The revised document, BWRVIP-190 Revision 1, was completely reformatted into two volumes, with a simplified presentation of water chemistry control, diagnostic and good practice parameters in Volume 1 and the technical bases in Volume 2, to facilitate use. The revision was developed in parallel and in coordination with preparation of the Fuel Reliability Guidelines Revision 1: BWR Fuel Cladding Crud and Corrosion. Guidance is included for plants operating under normal water chemistry (NWC), moderate hydrogen water chemistry (HWC-M), and noble metal application (GE-Hitachi NobleChem™) plus hydrogen injection. Volume 1 includes significant changes to BWR feedwater and reactor water chemistry control parameters to provide increased assurance of intergranular stress corrosion cracking (IGSCC) mitigation of reactor materials and fuel reliability during all plant conditions, including cold shutdown (≤200°F (93°C)), startup/hot standby (>200°F (93°C) and ≤ 10%) and power operation (>10% power). Action Level values for chloride and sulfate have been tightened to minimize environmentally assisted cracking (EAC) of all wetted surfaces, including those not protected by hydrogen injection, with or without noble metals. Chemistry control guidance has been enhanced to minimize shutdown radiation fields by clarifying targets for depleted zinc oxide (DZO) injection while meeting requirements for fuel reliability. Improved tabular presentations of parameter values explicitly indicate levels at which actions are to be taken and required sampling frequencies. Volume 2 provides the technical bases for BWR water chemistry control for control of EAC, flow accelerated corrosion

40 CFR 60.4124 - Hg budget permit revisions.

Science.gov (United States)

2010-07-01

... 40 Protection of Environment 6 2010-07-01 2010-07-01 false Hg budget permit revisions. 60.4124... Coal-Fired Electric Steam Generating Units Permits § 60.4124 Hg budget permit revisions. Except as provided in § 60.4123(b), the permitting authority will revise the Hg Budget permit, as necessary, in...

#FeesMustFall as social movement and emancipatory politics? Moving towards an apocalyptic theological praxis outside the limits of party politics

Directory of Open Access Journals (Sweden)

Felipe G.K. Buttelli

2017-11-01

Full Text Available This article proposes three reflexive movements. The first one offers an introduction to Fees Must Fall, pointing to some aspects that allow us to understand it as a social movement and some of its basic features. The second movement is a theoretical one, constructing the notion of emancipatory politics. It is based on the distinctions suggested by Jacques Rancière between ‘police and politics’ and by Michael Neocosmos between ‘excessive and expressive’ politics. It will also present the Freirean notion of ‘conscientisation and dialogicity’, emphasising the learning experience from the political praxis within emancipatory social movements. The third movement offers, as conclusion, an apocalyptic politics as suggested by Žižek, envisioned through the lens of Christian eschatology, as a critical approach to social movements towards the radical transformation of society.

A importância do perfil clínico-laboratorial no diagnóstico diferencial entre malária e hepatite aguda viral Importance of clinical and laboratory profiles for the differential diagnosis of malaria and acute viral hepatitis

Directory of Open Access Journals (Sweden)

Cacyane Naiff do Amaral

2003-10-01

Full Text Available OBJETIVOS: Destacar o perfil clínico-laboratorial de malária e hepatite aguda viral em dois grupos de crianças, ressaltando semelhanças e diferenças entre os dois quadros; subsidiar o aumento da sensibilidade clínica de presunção diagnóstica precoce de malária na infância. MÉTODOS: Foram estudados dois grupos de 30 crianças, de dois a dez anos de idade, portadoras de primo infecção malárica ou hepatite viral aguda, confirmados pela pesquisa de plasmódio e pesquisa de marcadores virais de hepatite A e B. As crianças foram submetidas às seguintes avaliações no primeiro dia de atendimento: hemograma, contagem de plaquetas, dosagem de enzimas hepáticas, uréia, creatinina e bilirrubinas. Os achados clínicos e laboratoriais foram descritos e comparados entre os dois grupos. Proporções de indivíduos com exames físicos alterados foram comparadas nos dois grupos, pelo teste exato de Fisher. RESULTADOS: A apresentação clínica inicial da doença foi semelhante em todos os pacientes: febre, cefaléia, sintomas digestivos e colúria. Metade dos portadores de malária não apresentou a tríade clássica, apesar de todos terem apresentado febre moderada ou alta, ao contrário dos portadores de hepatite. Na avaliação laboratorial, os portadores de malária apresentaram mais anemia e plaquetopenia quando comparados aos portadores de hepatite. Foram marcantes, nos portadores de hepatite, as elevações de bilirrubinas e enzimas hepáticas. CONCLUSÕES: A propedêutica detalhada e a avaliação criteriosa dos exames laboratoriais inespecíficos constituem peças fundamentais para a diferenciação clínica entre os dois diagnósticos, reforçando a identificação precoce do parasita e, conseqüentemente, o tratamento rápido de malária em crianças.OBJECTIVE: To establish clinical and diagnostic findings of malaria and acute viral hepatitis in children, stressing similarities and differences, so as to enhance the sensitivity of

La diástasis del tiempo real, entre el mito, la praxis y el éskhaton

Directory of Open Access Journals (Sweden)

Cencillo, Luis

2004-06-01

Full Text Available Unlike physical time, which is what docks measure, living time is multidimensional because it concerns the very being of the living. For the living human being, time is existing; his experiencing time is his experiencing the active rhythm of his existing. This experiencing varies as it is either individual or collective, subjectal or socially committed in a praxis that produces «a world.» There are several modes, levels or rhythms of time (e. g., existential, junctural, terminal, as there are several —personally lived— experiences in time, such as that of anticipation, rush, changing (developmentally or abruptly or aging. Mythical time is not an historical time, yet it is not unreal: explains the origins of a people and their institutions or a regular phenomenon. Lived real time is the active dynamics of joining a past that remains as the effect of «past» (but operative causes, unfolding toward a future that begins to appear before our eyes —sometimes against our will—, with a present that is tension and sudden movement for a project that is still unreal. Existing is an organic and structured totality (Gestalt, which will terminate because of its very nature as an articulated process.

A diferencia del tiempo físico, que es el que miden los relojes, el tiempo vital es múltiple, porque se trata del ser mismo del viviente. En el ser humano es el existir y su vivencia de tiempo es la vivencia de su ritmo vivo existiendo. Esta vivencia se diversifica en cuanto individual o en cuanto colectiva, en cuanto subjetal y en cuanto socialmente comprometida en una praxis productora de "mundo". Se pueden distinguir varias modalidades, niveles y ritmos de tiempo (v. g., un tiempo existencial, un tiempo coyuntural, un tiempo terminal, así como diversas experiencias personalmente vividas en el tiempo, como de anticipación, o de prisa, o de estar cambiando (evolutiva o abruptamente, o de envejecimiento. El tiempo mítico es un tiempo

A taxonomic revision of the genus Podocarpus

OpenAIRE

Laubenfels, de, D.J.

1985-01-01

In connection with the forthcoming revision of the Coniferae for the Flora Malesiana, the author thought it necessary to revise the genus Podocarpus. Although this genus has a substantial representation in Malesia (30 species), the revision is too involved to be appropriate with the Flora Malesiana per se. One new subgenus and 17 new sections are described, and 94 species are enumerated, of which 11 species and 1 variety are described as new, and 3 varieties have been raised to specific rank....

Revised Human Health Risk Assessment on Chlorpyrifos

Science.gov (United States)

We have revised our human health risk assessment and drinking water exposure assessment for chlorpyrifos that supported our October 2015 proposal to revoke all food residue tolerances for chlorpyrifos. Learn about the revised analysis.

REVISION PERMISSIABILITY IN CIVIL PROCEDURE IN REPUBLIC OF MACEDONIA

Directory of Open Access Journals (Sweden)

Marina Gligorova

2015-04-01

Full Text Available The revision as an extraordinary legal remedy is one more legal instrument for litigant in the effort to achieve protection of the rights or to defend against ungrounded claims of the other party. Litigants may declare revision of the litigation process due to substantive violations of the provisions of Civil Procedure and incorrect application of substantive law. Declaring revision because of a substantive violation of the provisions of Civil Procedure is limited. The purpose of this research paper is to investigate the most common reasons for filing revision of the litigation process in the period from June 2011 to June in 2012. The research includes what kind of reasons are often repeated, and the volume, or the number of reviews submitted to the Supreme Court of the Republic of Macedonia. As general hypothesis is that most of the adopted revisions are due to substantial violations of the provisions of civil procedure. Two-thirds of the stated revisions in front of the Supreme Court of Republic of Macedonia were rejected as unfounded and only one third of the submitted revisions from June 2011 to June 2012 were grounded. Since accepted revisions 59% due to incorrect application of substantive law, and 41% due to substantial violations of the provisions of Civil Procedure.

Test-Retest Reliability of the Parent Behavior Importance Questionnaire-Revised and the Parent Behavior Frequency Questionnaire-Revised

Science.gov (United States)

Mowder, Barbara A.; Shamah, Renee

2011-01-01

This study evaluated the test-retest reliability of two parenting measures: the Parent Behavior Importance Questionnaire-Revised (PBIQ-R) and Parent Behavior Frequency Questionnaire-Revised (PBFQ-R). These self-report parenting behavior assessment measures may be utilized as pre- and post-parent education program measures, with parents as well as…

Genesis of the Assif El Mal Zn-Pb (Cu, Ag) vein deposit. An extension-related Mesozoic vein system in the High Atlas of Morocco. Structural, mineralogical, and geochemical evidence

Science.gov (United States)

Bouabdellah, M.; Beaudoin, G.; Leach, D.L.; Grandia, F.; Cardellach, E.

2009-01-01

The Assif El Mal Zn-Pb (Cu-Ag) vein system, located in the northern flank of the High Atlas of Marrakech (Morocco), is hosted in a Cambro-Ordovician volcaniclastic and metasedimentary sequence composed of graywacke, siltstone, pelite, and shale interlayered with minor tuff and mudstone. Intrusion of synorogenic to postorogenic Late Hercynian peraluminous granitoids has contact metamorphosed the host rocks giving rise to a metamorphic assemblage of quartz, plagioclase, biotite, muscovite, chlorite, amphibole, chloritoid, and garnet. The Assif El Mal Zn-Pb (Cu-Ag) mineralization forms subvertical veins with ribbon, fault breccia, cockade, comb, and crack and seal textures. Two-phase liquid-vapor fluid inclusions that were trapped during several stages occur in quartz and sphalerite. Primary inclusion fluids exhibit Th mean values ranging from 104??C to 198??C. Final ice-melting temperatures range from -8.1??C to -12.8??C, corresponding to salinities of ???15 wt.% NaCl equiv. Halogen data suggest that the salinity of the ore fluids was largely due to evaporation of seawater. Late secondary fluid inclusions have either Ca-rich, saline (26 wt.% NaCl equiv.), or very dilute (3.5 wt.% NaCl equiv.) compositions and homogenization temperatures ranging from 75??C to 150??C. The ??18O and ??D fluid values suggest an isotopically heterogeneous fluid source involving mixing between connate seawater and black-shale-derived organic waters. Low ??13CVPDB values ranging from -7.5??? to -7.7??? indicate a homogeneous carbon source, possibly organic matter disseminated in black shale hosting the Zn-Pb (Cu-Ag) veins. The calculated ??34SH2S values for reduced sulfur (22.5??? to 24.3???) are most likely from reduction of SO42- in trapped seawater sulfate or evaporite in the host rocks. Reduction of sulfate probably occurred through thermochemical sulfate reduction in which organic matter was oxidized to produce CO2 which ultimately led to precipitation of saddle dolomite with

Maximum surgical blood ordering schedules for revision lower limb arthroplasty.

Science.gov (United States)

Mahadevan, Devendra; Challand, Christopher; Clarke, Andrew; Keenan, Jonathan

2011-05-01

Effective utilisation of blood products is fundamental. The introduction of maximum surgical blood ordering schedules (MSBOS) for operations has been shown to improve transfusion services. A retrospective analysis was undertaken to establish an evidence-based MSBOS for revision total hip replacement (THR) and total knee revision (TKR). The impact of this schedule on blood conservation was analysed. A retrospective analysis was undertaken on 397 patients who underwent revision THR and TKR over a 4-year period. The cross-match-to-transfusion ratio (CTR) and transfusion index (TI) were calculated. A MSBOS protocol was created based on the TIs and its' impact on transfusion services was assessed prospectively on 125 patients by comparing CTRs. In revision THR, TI was 1.19 for elective cases, 1.55 for emergency cases and 2.35 for infected cases. There was no difference in TI for revisions of cemented and uncemented components. Single component THR revision required less transfusion. In revision TKR, TI was 0.31 for elective cases, 2.0 for emergency cases and 1.23 for cases with infection. The introduction of the MSBOS protocol had resulted in a considerable improvement in blood ordering. Reductions in the CTR were seen for all types of revision surgery, but most evident in elective revision THR (3.24-2.18) and elective revision TKR (7.95-1.2). Analysis confirmed that excessive cross-matching occurred for revision lower limb arthroplasty. The introduction of our MSBOS protocol promoted blood conservation and compliance with established national guidelines.

Risk factors for total hip arthroplasty aseptic revision.

Science.gov (United States)

Khatod, Monti; Cafri, Guy; Namba, Robert S; Inacio, Maria C S; Paxton, Elizabeth W

2014-07-01

The purpose of this study was to evaluate patient, operative, implant, surgeon, and hospital factors associated with aseptic revision after primary THA in patients registered in a large US Total Joint Replacement Registry. A total of 35,960 THAs registered from 4/2001-12/2010 were evaluated. The 8-year survival rate was 96.7% (95% CI 96.4%-97.0%). Females had a higher risk of aseptic revision than males. Hispanic and Asian patients had a lower risk of revision than white patients. Ceramic-on-ceramic, ceramic-on-conventional polyethylene, and metal-on-conventional polyethylene bearing surfaces had a higher risk of revision than metal-on-highly cross-linked polyethylene. Body mass index, health status, diabetes, diagnosis, fixation, approach, bilateral procedures, head size, surgeon fellowship training, surgeon and hospital volume were not revision risk factors. Copyright © 2014 Elsevier Inc. All rights reserved.

Práxis de comunidade orgânica no trabalho: uma estratégia que melhora a performance da empresa / Praxis for community organic at work: a strategiy that improvies performance of the company

Directory of Open Access Journals (Sweden)

Jacir Leonir Casagrande

2013-05-01

Full Text Available Esta pesquisa, de abordagem qualitativa e do tipo estudo de caso, teve como objetivo compreender a práxis de comunidade orgânica desenvolvida no ambiente de trabalho de uma empresa brasileira e a relação com a qualidade de vida de seus trabalhadores. Os dados foram coletados no ambiente laboral, junto a 125 trabalhadores, por meio de observação participante e entrevistas. A análise dos dados, seguindo diretrizes qualitativas, foi conduzida pela técnica de identificação de categorias. A primeira análise mostra a dinâmica do ambiente laboral como uma práxis que é construída no cotidiano das diversas interações de trabalho. O processo de análise-reflexão-síntese dessa práxis evidencia um conjunto de categorias de dimensão técnico-humanística, que se caracteriza como um “construto de comunidade orgânica”. Essa práxis repercute na melhoria da qualidade de vida dos trabalhadores, no ambiente laboral e fora dele, e também na vida da própria empresa. As concepções teórico-metodológicas evidenciadas no estudo se constituem como um referencial para análise de contextos de trabalho, com vistas a diagnosticar as condições do ambiente laboral e também a gerar reflexões no contexto acadêmico e organizacional, visando a suscitar pesquisas sobre a temática e a aplicação do construto de comunidade orgânica no cotidiano de organizações com a finalidade de promover a saúde da população envolvida.Qualitative approach research, case-study, whose objective was to understand the organic community praxis performed in the workplace of a Brazilian company, and its relationship towards the quality of life of their employees. The data were collected from 125 employees of the company through participating observation and interview. The data analysis, following qualitative guidelines, was conducted with the aid of a class identification technique. The first analysis shows the dynamics of the work atmosphere as a praxis built

De Los Libros a Comunicación y cultura Praxis editorialista y proyecto intelectual en el itinerario de Héctor Schmucler

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Mariano Zarowsky

2016-05-01

Full Text Available [es] Nos proponemos reconstruir algunos momentos claves del itinerario intelectual de Héctor Schmucler. Su figura es productiva para poner de relieve el modo en que la emergencia de los estudios en comunicación y cultura en la Argentina se configura sobre una trama político-cultural que la contiene y desde la que este espacio de saber especializado se autonomiza. De Pasado y Presente (1963-1965 a Comunicación y cultura (1973-1985, pasando por su papel en la revista Los Libros (que fundó y dirigió entre 1969 y 1972, el itinerario de Héctor Schmucler, en especial su praxis editorialista, constituye un mirador privilegiado para seguir este proceso de múltiples aristas. En tanto nos interrogamos por las condiciones sociales de producción del conocimiento sobre lo social, se aspira a dar cuenta del espacio de cruces de discursos y saberes, de tradiciones intelectuales y político-culturales desde las que se recortan los estudios en comunicación y cultura en el país. Asimismo, se trata de pensar su historia como una entrada sugerente para abordar movimientos más amplios del campo político y cultural. [en] The present article attempts to reconstruct some of the key moments in Héctor Schmucler’s intellectual life. Studying Schmucler activity will help us to productively highlight the way in which Argentine communication and culture studies are contained within a political-cultural framework, from which it acquires autonomy as an independent knowledge corpus. Schmucler’s work, specially his publishing praxis, featuring the magazines Pasado y presente (1963–1965, Los libros (founded and headed by Schmucler between 1969 and 1972, and Comunicación y cultura (1973–1985, offers a privileged outlook on this multi-sided process. This article attempts to approach the encounter between discourses and knowledge corpora, as well as between intellectual and political-cultural traditions, that Argentine communication and culture studies emerge

Revision of infected knee arthroplasties in Denmark

DEFF Research Database (Denmark)

Lindberg-Larsen, Martin; Jørgensen, Christoffer C; Bagger, Jens

2016-01-01

Background and purpose - The surgical treatment of periprosthetic knee infection is generally either a partial revision procedure (open debridement and exchange of the tibial insert) or a 2-stage exchange arthroplasty procedure. We describe the failure rates of these procedures on a nationwide...... basis. Patients and methods - 105 partial revisions (100 patients) and 215 potential 2-stage revision procedures (205 patients) performed due to infection from July 1, 2011 to June 30, 2013 were identified from the Danish Knee Arthroplasty Register (DKR). Failure was defined as surgically related death...

75 FR 60485 - NRC Enforcement Policy Revision

Science.gov (United States)

2010-09-30

... NUCLEAR REGULATORY COMMISSION [NRC-2008-0497] NRC Enforcement Policy Revision AGENCY: Nuclear Regulatory Commission. ACTION: Policy statement. SUMMARY: The Nuclear Regulatory Commission (NRC or Commission) is publishing a major revision to its Enforcement Policy (Enforcement Policy or Policy) to...

[Revised practice guideline 'Anaemia in midwifery practice'

NARCIS (Netherlands)

Beentjes, M.; Jans, S.M.P.J.

2012-01-01

The practice guideline of the Royal Dutch Organization of Midwives 'Anaemia in primary care midwifery practice' published in 2000, has recently been revised. The revised guideline takes physiological haemodilution during pregnancy into consideration and provides gestation specific reference values

Surto de malária por Haemoproteus columbae em pombos An outbreak of malaria by Haemoproteus columbae in pigeons

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J.S. Resende

2001-06-01

Full Text Available Relata-se um surto de malária por Haemoproteus columbae em pombos-correio (Columba livia, caracterizado por um quadro agudo com mortalidade de 3% ao dia em aves de aspecto saudável ou crônico com prostração e fraqueza. O exame clínico das aves doentes evidenciou sinusite e conjuntivite e à necropsia traqueíte hemorrágica, aerossaculite, esplenomegalia, nefromegalia e hepatomegalia com hemorragias. O díptero hematófago da família Hippoboscidae Pseudolynchia canariensis foi encontrado inserido entre as penas dos indivíduos. Esfregaços de sangue periférico e cardíaco e impressões de baço e fígado corados por Giemsa permitiram a visualização de inclusões intraeritrocitárias características de Haemoproteus columbae

Analysis of NRC Regulatory Guide 1.21 Revision 2

Energy Technology Data Exchange (ETDEWEB)

Kim, Sung Il; Yook, Dae Sik; Lee, Byung Soo [KINS, Daejeon (Korea, Republic of)

2015-05-15

It is essential to have a degree of uniformity in the methods used for measuring, evaluating, recording, and reporting data on radioactive material in effluents and solid wastes. For this purpose, the U.S. Nuclear Regulatory Commission (NRC) released a revised version of the Regulatory Guide 1.21 'Measuring, evaluating, and reporting radioactive material in liquid and gaseous effluents and solid waste' (revision 2) in 2009, updating the revision 1 version released in 1974. This study compares the previous revision 1 (1974) version with the revision 2 (2009) version to elaborate on the application of the guidelines to Korea. This study consists of an analysis of the 2009 Revision 2 version of the U.S. NRC Regulatory Guidelines 1.21 and an exposition of methods for its application in the domestic environment. Major revisions were made to allow for the adoption of a risk informed approach. Radionuclides with lower than 1% contribution to emission or radiation levels can be selected as principal radionuclides. Requirements for analysis of leaks and spills have been reinforced, with additional groundwater monitoring and hydrological data analysis becoming necessary.

Efeitos benéficos e maléficos da malva sylvestris

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Ana Carolina Locatelli Ecker

2016-04-01

Full Text Available Objetivo. Revisar os efeitos benéficos e maléficos da Malva sylvestris para a saúde humana. Materiais e métodos. Foi realizada uma busca na base de dados BIREME, em setembro de 2014, por meio das pala­vras chaves malva AND sylvestris. Foram incluídos os artigos na língua inglesa e portuguesa sem limite de tempo. Foram excluídos os estudos repetidos e aqueles que não abordavam o tema. Resultados. Atra­vés da busca realizada, foram encontrados 56 artigos, destes, foram excluídos dois repetidos, um por encontrar-se no idioma chinês e, 41 por estarem fora do tema (benefícios para animais e solo, proprie­dades químicas da erva, pesquisa em campo de determinadas regiões do mundo abrangendo índices de utilização de muitas espécies de plantas para fins medicinais. Assim, foram, incluídos 12 artigos. Com grande importância terapêutica, a erva tem sido utilizada na área da saúde em geral para inflamações internas e externas, fins quimio-preventivos e antissépticos. Também alivia secreções como catarros, congestionamento das vias respiratórias e age como calmante no sistema neurológico. Segundo pes­quisas, o chá de malva apresenta resultados mais vantajosos do que tratamentos medicamentosos e é uma das mais utilizadas como auto-medicação. Conclusão. A Malva sylvestris é utilizada para muitos fins benéficos para o ser humano desde tempos remotos, mas sua comprovação científica tem ocorrido atualmente, evidenciando a veracidade de suas vantagens na saúde e no tratamento de patologias.

EJERCICIO Y LA DETECCION DEL MAL AGUDO DE MONTAÑA GRAVE

Science.gov (United States)

Garófoli, Adrián; Montoya, Paola; Elías, Carlos; Benzo, Roberto

2012-01-01

El Mal Agudo de Montaña (MAM) es un conjunto de síntomas inespecíficos padecidos por sujetos que ascienden rápidamente desde baja a alta altura sin adecuada aclimatación. Usualmente es autolimitado, pero las formas graves (edema pulmonar y cerebral) pueden causar la muerte. La hipoxemia exagerada en reposo está relacionada con el desarrollo de MAM pero su valor predictivo es limitado. Dado que el ejercicio en altura se acompaña de mayor hipoxemia y síntomas, postulamos el valor predictivo de un simple test de ejercicio para pronosticar MAM grave. Se estudió el valor predictivo de la saturación de oxígeno en reposo y ejercicio submáximo a 2 700m y 4 300m en 63 sujetos que ascendían al cerro Aconcagua (6 962m). Se consideró desaturación de oxígeno con ejercicio a una disminución >=5% respecto al reposo. Se utilizó la escala de Lake-Louise para establecer la presencia de MAM grave. 6 sujetos presentaron MAM grave (9.5%) y requirieron evacuación. La saturación de oxígeno en reposo a 2 700m no fue significativa para clasificar sujetos que luego desarrollaron MAM grave. Por el contrario, la asociación de desaturación durante el ejercicio a 2 700m más la saturación inapropiada en reposo a 4 300m fue significativa para clasificar a los sujetos que desarrollaron MAM grave con un valor predictivo positivo de 80% y un valor predictivo negativo del 97%. Nuestros resultados son relevantes para el montañismo y sugieren la adición de un simple test de ejercicio en la predicción del MAM grave. PMID:20228017

Construindo o estado de conhecimento do bem-estar e mal-estar docente na revista de educação da PUCRS = Building the state of knowledge of teachers well-being and burnout in "Revista Educação" of PUCRS

Directory of Open Access Journals (Sweden)

Pinheiro, Leandro Brum

2011-01-01

Full Text Available A imprensa atual tem retratado diversas situações de professores e alunos em alto nível de mal-estar: stress, violência, rendimento baixo nas avaliações institucionais, perda do valor da profissão docente, entre outros. Todavia, a Academia tem resgatado também as diversas tentativas de compreensão e promoção do bem-estar na escola. A Pontifícia Universidade Católica do Rio Grande do Sul, através da Revista Educação, tem tratado destes dois temas com séria análise contextual e profundidade científica, sendo por isso escolhida como a fonte de pesquisas deste artigo. Com o fim de analisar a construção do estado de conhecimento do bem-estar e mal-estar docente na citada revista, tomamos desde o primeiro caderno publicado (1978 até o mais recente (2009, selecionando os artigos sobre as temáticas e organizando-os em seis categorias: a década em que foi escrito, os autores e suas universidades de origem, a classificação dos artigos em resultados de pesquisa ou de revisão bibliográfica, os autores mais citados e a temática dominante – o bem-estar ou o mal-estar docente. A partir das categorizações levantadas para os nove artigos selecionados, observou-se que a produção destes começou a se tornar mais frequente a partir dos anos 90, em especial com contribuições de professores da PUCRS e da Universidade do Algarve – Portugal. A maioria destes artigos era de revisão bibliográfica. Outra conclusão importante é que houve, a partir do início desta década, uma preocupação maior com o bem-estar docente do que propriamente com o mal-estar docente. Assim, é nosso desejo que este artigo possa promover futuras pesquisas nesta área, enfatizando o bem-estar dos professores, consolidando a tendência mundial das publicações sobre o tema

Sustainable development - theory and practice of environmental consulting. Proceedings of a seminar of Zentrale Informationsstelle Umweltberatung Bayern. Vol. 11; Nachhaltige Entwicklung - Theorie und Praxis fuer die Umweltberatung. Seminarband der Zentralen Informationsstelle Umweltberatung Bayern. Bd. 11

Energy Technology Data Exchange (ETDEWEB)

Koller, U.; Behling, G.; Klemmer, A.; Haury, H.J. [comps.

1998-12-31

On 25/26 November, 1997, Zentrale Informationsstelle, Umweltberatung Bayern held its 11th seminar under the title ``Sustainable development - theory and practice of environmental consulting. Subjects related to the Agenda 21 were discussed in lectures and workshops. [Deutsch] Am 25. und 26. November 1997 veranstaltete die Zentrale Informationsstelle, Umweltberatung Bayern ihr elftes Seminar mit dem Thema ``Nachhaltige Entwicklung- Theorie und Praxis fuer die Umweltberatung``. In Fachvortraegen und Workshops wurden Themen zur Agenda 21 behandelt. (ABI)

Belief Revision in the GOAL Agent Programming Language

DEFF Research Database (Denmark)

Spurkeland, Johannes Svante; Jensen, Andreas Schmidt; Villadsen, Jørgen

2013-01-01

Agents in a multiagent system may in many cases find themselves in situations where inconsistencies arise. In order to properly deal with these, a good belief revision procedure is required. This paper illustrates the usefulness of such a procedure: a certain belief revision algorithm is consider...... in order to deal with inconsistencies and, particularly, the issue of inconsistencies, and belief revision is examined in relation to the GOAL agent programming language....

Current Epidemiology of Revision Total Knee Arthroplasty in the United States.

Science.gov (United States)

Delanois, Ronald E; Mistry, Jaydev B; Gwam, Chukwuweike U; Mohamed, Nequesha S; Choksi, Ujval S; Mont, Michael A

2017-09-01

Revision surgery for failed total knee arthroplasty (TKA) continues to pose a substantial burden for the United States healthcare system. The predominant etiology of TKA failure has changed over time and may vary between studies. This report aims to update the current literature on this topic by using a large national database. Specifically, we analyzed: (1) etiologies for revision TKA; (2) frequencies of revision TKA procedures; (3) various demographics including payer type and region; and (4) the length of stay (LOS) and total charges based on type of revision TKA procedure. The Healthcare Cost and Utilization Project (HCUP) National Inpatient Sample (NIS) database was used to identify all revision TKA procedures performed between 2009 and 2013. Clinical, economic, and demographic data were collected and analyzed for 337,597 procedures. Patients were stratified according to etiology of failure, age, sex, race, US census region, and primary payor class. The mean LOS and total charges were also calculated. Infection was the most common etiology for revision TKA (20.4%), closely followed by mechanical loosening (20.3%). The most common revision TKA procedure performed was all component revision (31.3%). Medicare was the primary payor for the greatest proportion of revisions (57.7%). The South census region performed the most revision TKAs (33.2%). The overall mean LOS was 4.5 days, with arthrotomy for removal of prosthesis without replacement procedures accounting for the longest stays (7.8 days). The mean total charge for revision TKAs was $75,028.07. Without appropriate measures in place, the burden of revision TKAs may become overwhelming and pose a strain on providers and institutions. Continued insight into the etiology and epidemiology of revision TKAs may be the principle step towards improving outcomes and mitigating the need for future revisions. Copyright © 2017 Elsevier Inc. All rights reserved.

Structure, microstructure and determination of optical constants from transmittance data of co-doped Zn0.90Co0.05M0.05O (M=Al, Cu, Cd, Na) films

International Nuclear Information System (INIS)

2 A Laboratoire des Structures, Propriétés et Interactions Inter Atomiques, Université Abbes Laghrour, Khenchela 40000 (Algeria))" data-affiliation=" (LASPI2 A Laboratoire des Structures, Propriétés et Interactions Inter Atomiques, Université Abbes Laghrour, Khenchela 40000 (Algeria))" >Roguai, S.; 2 A Laboratoire des Structures, Propriétés et Interactions Inter Atomiques, Université Abbes Laghrour, Khenchela 40000 (Algeria))" data-affiliation=" (LASPI2 A Laboratoire des Structures, Propriétés et Interactions Inter Atomiques, Université Abbes Laghrour, Khenchela 40000 (Algeria))" >Djelloul, A.; Nouveau, Corinne; Souier, T.; Dakhel, A.A.; Bououdina, M.

2014-01-01

Highlights: • A series of Zn 0.90 Co 0.05 M 0.05 O (M=Al, Cu, Cd, Na) films has been prepared. • Thin films of these prepared samples have been deposited using USP technique. • Absorption of electronic transition has been used to fit the transmittance data. • Optical and dispersion parameters have been determined. - Abstract: ZnO, Zn 0.95 Co 0.05 O and Zn 0.90 Co 0.05 M 0.05 O (M=Al, Cd, Na, Cu) single phase films have been successfully synthesized by ultrasonic spray pyrolysis technique. Structural analysis by X-ray diffraction show that all the films have hexagonal wurtzite structure with an average crystallite size in the range of 19–25 nm. SEM analysis revealed that Cd and Na preserve the shape of nanopetals observed with ZnO or Co-ZnO films, while the doping with Al or Cu promote the formation of dense films constituted of nanorods. By the application of Levenberg–Marquardt least square method, the experimental transmittance data were fitted perfectly with the transmittance data calculated via a combination of Wemple–DiDomenico model, absorption coefficient of an electronic transition and Tauc–Urbach model. The concentration of absorbing centres N Co and oscillator strength f of d–d transition of Co 2+ ions are calculated from Smakula’s formula

Planned revision to DOE Order 5820.2A, Radioactive Waste Management

Energy Technology Data Exchange (ETDEWEB)

Duggan, G.J. [Dept. of Energy, Washington, DC (United States); Williams, R.E.; Kudera, D.E. [EG and G Idaho, Inc., Idaho Falls, ID (United States). Idaho National Engineering Lab.; Bailey, D.E. [NJG, Inc. (United States)

1993-03-01

US Department of Energy Headquarters initiated efforts to revise DOE Order 5820.2A, ``Radioactive Waste Management``. The purpose of the revision is to enhance DOE waste management requirements, reflect new DOE organizational responsibilities, and consolidate requirements for management of all waste, under the responsibility of Environmental Restoration and Waste Management, into a single order. This paper discusses the revision philosophy, objectives of the revision, and strategy for the revision. Issues being considered for inclusion in the revision and recommended methods of resolving each issue are also discussed.

Descriptor revision belief change through direct choice

CERN Document Server

Hansson, Sven Ove

2017-01-01

This book provides a critical examination of how the choice of what to believe is represented in the standard model of belief change. In particular the use of possible worlds and infinite remainders as objects of choice is critically examined. Descriptors are introduced as a versatile tool for expressing the success conditions of belief change, addressing both local and global descriptor revision. The book presents dynamic descriptors such as Ramsey descriptors that convey how an agent’s beliefs tend to be changed in response to different inputs. It also explores sentential revision and demonstrates how local and global operations of revision by a sentence can be derived as a special case of descriptor revision. Lastly, the book examines revocation, a generalization of contraction in which a specified sentence is removed in a process that may possibly also involve the addition of some new information to the belief set.

El mal en las palabras: El hombre tempestad Evil in Words: El hombre tempestad

Directory of Open Access Journals (Sweden)

Ángela Uribe Botero

2009-06-01

Full Text Available En este trabajo se muestra cómo es posible que el mal pueda estar contenido en cierta forma de hablar. En términos de J. L. Austin, y de la mano de Hannah Arendt, a la luz de un ejemplo tomado de la historia colombiana, se ilustra la fuerza ilocucionaria de ciertas expresiones. El ejemplo está contenido en uno de los discursos más célebres del expresidente colombiano Laureano Gómez Castro. El texto concluye mostrando cómo, con los enunciados que Gómez emite, antes que cumplir las promesas que hace en su discurso o describir una serie de cosas, miente y en tanto hace esto, cambia el mundo en la forma de actuar sobre él con maldad.This text shows how evil can be contained in certain way of speaking. In terms of J. L. Austin, and considering Hannah Arendt, with the help of an example taken from recent Colombian history, it illustrates the ilocucionary force of certain expressions. The example is found in one of the most important speeches of former president Laureano Gómez Castro. The text concludes by showing how, Gómez, rather than maintaining promises that he makes in his speech or describing a series of things, lies, and in so doing, changes the world through his way of evilly acting above it.

Quema de libros y antitotalitarismo. Manuel Rivas Los libros arden mal y Ray Bradbury Fahrenheit 451

Directory of Open Access Journals (Sweden)

Mechthild Albert

2015-07-01

Full Text Available El presente artículo se propone comparar dos novelas cuyo común denominador es el compromiso antitotalitario con motivo de la quema de libros considerada como el culmen de la barbarie anticultural, a saber Los libros arden mal (2006 de Manuel Rivas y Fahrenheit 451 (1953 de Ray Bradbury. Partiendo de las reflexiones de Fernando Rodríguez de la Flor en torno al biblioclasmo (2004, el paralelo se centra en los siguientes aspectos: la descripción zoo- y antropomorfizada de los libros en llamas; el biblioclasmo como expresión del totalitarismo, denotando asimismo una relación ambivalente y dialéctica entre cultura y barbarie; los movimientos subversivos dedicados a mantener el culto al libro y la tradición filosófico-literaria; la intertextualidad y el papel destacado de la Biblia en cuanto Libro de los libros. En conclusión se podrá constatar que, a pesar de numerosos puntos en común, en particular su compromiso antitotalitario, ambos autores se distinguen en concreto por su orientación política y el enfoque de su crítica cultural

Explanatory Coherence and Belief Revision in Naive Physics

Science.gov (United States)

1988-07-01

continental drift (Thagard & Nowak, 1988), and debates about why the dinosaurs became extinct . Application of ECHO to the belief revisions in Pat and Hal...rewono of nocuamy Idid 4onoly by bodck number) Students of reasoning have long tried to understand how people revise systems of beliefs. We maintain...Princeton University Students of reasoning have long tried to understand how people revise systems of beliefs (see Wertheimer, 1945, for example). We will

Results of revision anterior shoulder stabilization surgery in adolescent athletes.

Science.gov (United States)

Blackman, Andrew J; Krych, Aaron J; Kuzma, Scott A; Chow, Roxanne M; Camp, Christopher; Dahm, Diane L

2014-11-01

The purpose of this study was to determine failure rates, functional outcomes, and risk factors for failure after revision anterior shoulder stabilization surgery in high-risk adolescent athletes. Adolescent athletes who underwent primary anterior shoulder stabilization were reviewed. Patients undergoing subsequent revision stabilization surgery were identified and analyzed. Failure rates after revision surgery were assessed by Kaplan-Meier analysis. Failure was defined as recurrent instability requiring reoperation. Functional outcomes included the Marx activity score; American Shoulder and Elbow Surgeons score; and University of California, Los Angeles score. The characteristics of patients who required reoperation for recurrent instability after revision surgery were compared with those of patients who required only a single revision to identify potential risk factors for failure. Of 90 patients who underwent primary anterior stabilization surgery, 15 (17%) had failure and underwent revision surgery (mean age, 16.6 years; age range, 14 to 18 years). The mean follow-up period was 5.5 years (range, 2 to 12 years). Of the 15 revision patients, 5 (33%) had recurrent dislocations and required repeat revision stabilization surgery at a mean of 50 months (range, 22 to 102 months) after initial revision. No risk factors for failure were identified. The Kaplan-Meier reoperation-free estimates were 86% (95% confidence interval, 67% to 100%) at 24 months and 78% (95% confidence interval, 56% to 100%) at 48 months after revision surgery. The mean final Marx activity score was 14.8 (range, 5 to 20); American Shoulder and Elbow Surgeons score, 82.1 (range, 33 to 100); and University of California, Los Angeles score, 30.8 (range, 16 to 35). At 5.5 years' follow-up, adolescent athletes had a high failure rate of revision stabilization surgery and modest functional outcomes. We were unable to convincingly identify specific risk factors for failure of revision surgery. Level IV

Plan-Belief Revision in Jason

DEFF Research Database (Denmark)

Jensen, Andreas Schmidt; Villadsen, Jørgen

2015-01-01

When information is shared between agents of unknown reliability, it is possible that their belief bases become inconsistent. In such cases, the belief base must be revised to restore consistency, so that the agent is able to reason. In some cases the inconsistent information may be due to use of...... of incorrect plans. We extend work by Alechina et al. to revise belief bases in which plans can be dynamically added and removed. We present an implementation of the algorithm in the AgentSpeak implementation Jason....

Revised Huang-Yang multipolar pseudopotential

International Nuclear Information System (INIS)

Derevianko, Andrei

2005-01-01

A number of authors have recently pointed out inconsistencies of results obtained with the Huang-Yang multipolar pseudopotential for low-energy scattering [K. Huang and K. C. Yang, Phys. Rev. 105, 767 (1957); later revised by Huang, Statistical Mechanics (Wiley, New York, 1963)]. The conceptual validity of their original derivation has been questioned. Here I show that these inconsistencies are rather due to an algebraic mistake made by Huang and Yang. With the corrected error, I present the revised version of the multipolar pseudopotential

Trends in Revision Elbow Ulnar Collateral Ligament Reconstruction in Professional Baseball Pitchers.

Science.gov (United States)

Wilson, Alexander T; Pidgeon, Tyler S; Morrell, Nathan T; DaSilva, Manuel F

2015-11-01

To determine the frequency of revision elbow ulnar collateral ligament (UCL) reconstruction in professional baseball pitchers. Data were collected on 271 professional baseball pitchers who underwent primary UCL reconstruction. Each player was evaluated retrospectively for occurrence of revision UCL reconstructive surgery to treat failed primary reconstruction. Data on players who underwent revision UCL reconstruction were compiled to determine total surgical revision incidence and revision rate by year. The incidence of early revision was analyzed for trends. Average career length after primary UCL reconstruction was calculated and compared with that of players who underwent revision surgery. Logistic regression analysis was performed to assess risk factors for revision including handedness, pitching role, and age at the time of primary reconstruction. Between 1974 and 2014, the annual incidence of primary UCL reconstructions among professional pitchers increased, while the proportion of cases being revised per year decreased. Of the 271 pitchers included in the study, 40 (15%) required at least 1 revision procedure during their playing career. Three cases required a second UCL revision reconstruction. The average time from primary surgery to revision was 5.2 ± 3.2 years (range, 1-13 years). The average length of career following primary reconstruction for all players was 4.9 ± 4.3 years (range, 0-22 years). The average length of career following revision UCL reconstruction was 2.5 ± 2.4 years (range, 0-8 years). No risk factors for needing revision UCL reconstruction were identified. The incidence of primary UCL reconstructions among professional pitchers is increasing; however, the rate of primary reconstructions requiring revision is decreasing. Explanations for the decreased revision rate may include improved surgical technique and improved rehabilitation protocols. Therapeutic IV. Copyright © 2015 American Society for Surgery of the Hand. Published by

Reposição cirúrgico-ortopédica de implante mal posicionado: relato de caso Surgical-orthopedic repositioning of malpositioned implant: a case report

Directory of Open Access Journals (Sweden)

Luiz Carlos Ferreira da Silva

2005-06-01

Full Text Available A reabilitação bucal por meio da colocação de implantes dentários tem se tornado um procedimento freqüente da clínica odontológica. Falhas no planejamento ou na execução da técnica podem levar a casos onde, apesar de osseointegrado, o implante não apresenta condições de restauração satisfatória devido ao seu mal posicionamento. Diversos autores têm relatado a possibilidade de se utilizar osteotomias segmentares de maxila ou mandíbula para reposicionar um segmento alveolar com implante, mostrando que esta pode ser uma técnica efetiva e previsível para restaurar implantes em posição anatômica comprometida. O presente trabalho apresenta o caso clínico de uma paciente de 20 anos de idade onde foi realizada osteotomia segmentar de maxila associada à distração osteogênica para correção de um implante mal posicionado.Oral rehabilitation through dental implants has become a common procedure at dental practice. However, if the implant is placed in an inappropriate position either because of inadequate presurgical planning or poor surgical technique, it may be unrestorable in spite of osseointegrated. Many authors have reported the possibility of using segmental maxillary or mandibular osteotomies to reposition an alveolar segment with its implants. This can be an effective, predictable technique for restoring implants in a compromised anatomic position. This paper presents a case report describing the use of this procedure associated to distraction osteogeneis to reposition one malpositioned implant in a 20 years old girl.

Investigación en didáctica de la física: tendencias actuales e incidencia en la formación del profesorado

OpenAIRE

García Carmona, Antonio

2009-01-01

En este artículo se hace una revisión de las tendencias actuales en investigación en didáctica de la Física. Se destaca la enseñanza de la Física como una actividad investigadora y la reflexión sobre la práctica como instrumento eficaz para el autodesarrollo profesional del profesorado de Física. This paper presents a revision of actually tendencies on research in physics education. Physics teaching as an inquiry activity and reflection about the teaching praxis as an effective in...

The nuclear liability conventions revised

International Nuclear Information System (INIS)

Reyners, P.

2004-01-01

The signature on 12 February 2004 of the Protocols amending respectively the 1960 Paris Convention and the 1963 Brussels Supplementary Convention was the second step of the process of modernisation of the international nuclear liability regime after the adoption in September 1997 of a Protocol revising the 1963 Vienna Convention and of a new Convention on Supplementary Compensation for Nuclear Damage. The common objective of the new instruments is to provide more funds to compensate a larger number of potential victims in respect of a broader range of damage. Another goal of the revision exercise was to maintain the compatibility between the Paris and Vienna based systems, a commitment enshrined in the 1988 Joint Protocol, as well as to ascertain that Paris/Brussels countries could also become a Party to the Convention on Supplementary Compensation. However, while generally consistent vis a vis the Joint Protocol, the provisions of the Paris and Vienna Conventions, as revised, differ on some significant aspects. Another remaining issue is whether the improved international nuclear liability regime will succeed in attracting in the future a larger number of countries, particularly outside Europe, and will so become truly universal. Therefore, the need for international co-operation to address these issues, to facilitate the adoption of new implementing legislation and to ensure that this special regime keeps abreast of economic and technological developments, is in no way diminished after the revision of the Conventions.(author)

Sequenced Peer Revision: Creating Competence and Community

Science.gov (United States)

Bowman, Ingrid K.; Robertson, John

2013-01-01

Mastering techniques of self- and peer revision is a valuable tool for all writers, especially US-educated Generation 1.5 students, whose near fluency enables them to dialogue successfully about their writing. Using action research, 2 academic writing instructors systematically trained students to more responsibly and effectively revise their…

Quantum interaction. Revised selected papers

International Nuclear Information System (INIS)

Song, Dawei; Zhang, Peng; Wang, Lei; Arafat, Sachi

2011-01-01

This book constitutes the thoroughly refereed post-conference proceedings of the 5th International Symposium on Quantum Interaction, QI 2011, held in Aberdeen, UK, in June 2011. The 26 revised full papers and 6 revised poster papers, presented together with 1 tutorial and 1 invited talk were carefully reviewed and selected from numerous submissions during two rounds of reviewing and improvement. The papers show the cross-disciplinary nature of quantum interaction covering topics such as computation, cognition, mechanics, social interaction, semantic space and information representation and retrieval. (orig.)

Fast-track revision knee arthroplasty

DEFF Research Database (Denmark)

Husted, Henrik; Otte, Niels Kristian Stahl; Kristensen, Billy B

2011-01-01

Abstract Background and purpose Fast-track surgery has reduced the length of hospital stay (LOS), morbidity, and convalescence in primary hip and knee arthroplasty (TKA). We assessed whether patients undergoing revision TKA for non-septic indications might also benefit from fast-track surgery....... Methods 29 patients were operated with 30 revision arthroplasties. Median age was 67 (34-84) years. All patients followed a standardized fast-track set-up designed for primary TKA. We determined the outcome regarding LOS, morbidity, mortality, and satisfaction. Results Median LOS was 2 (1-4) days...

Quantum interaction. Revised selected papers

Energy Technology Data Exchange (ETDEWEB)

Song, Dawei; Zhang, Peng; Wang, Lei [Aberdeen Univ. (United Kingdom). School of Computing; Melucci, Massimo [Padua Univ., Padova (Italy). Dept. of Information Engineering; Frommholz, Ingo [Bedfordshire Univ. (United Kingdom); Arafat, Sachi (eds.) [Glasgow Univ. (United Kingdom). School of Computing Science

2011-07-01

This book constitutes the thoroughly refereed post-conference proceedings of the 5th International Symposium on Quantum Interaction, QI 2011, held in Aberdeen, UK, in June 2011. The 26 revised full papers and 6 revised poster papers, presented together with 1 tutorial and 1 invited talk were carefully reviewed and selected from numerous submissions during two rounds of reviewing and improvement. The papers show the cross-disciplinary nature of quantum interaction covering topics such as computation, cognition, mechanics, social interaction, semantic space and information representation and retrieval. (orig.)

Medical writing, revising and editing

DEFF Research Database (Denmark)

Pilegaard, Morten

2006-01-01

The globalization of science makes medical writing, editing and revision a rapidly growing field of linguistic study and practice. Medical science texts are written according to uniform, general guidelines and medical genres have become highly conventionalized in terms of structure and linguistic...... form. Medical editing often takes the form of peer review and mainly addresses issues of contents and overall validity. Medical revision incorporates the checking of the macrostructure and the microstructure of the text, its language and style and its suitability for the target reader or client...

Microbiological diagnosis in revision of infected knee arthroplasties in Denmark

DEFF Research Database (Denmark)

Lindberg-Larsen, Martin; Pitter, Frederik Taylor; Voldstedlund, Marianne

2017-01-01

. METHODS: One hundred and two partial revisions (open debridement and exchange of tibial insert) and 213 two-stage procedures performed due to infection in 275 patients from 1 July 2011 to 30 June 2013 were included and analysed by linkage to data from a nationwide registry on microbiological test results....... RESULTS: 78 (24.8%) revisions were culture negative, 192 (60.9%) showed monomicrobial growth and 43 (14.3%) polymicrobial growth. Staphylococcus aureus was the most frequent isolate in mono-culture in 70 (22.2%) revisions and in polymicrobial culture in 15 revisions with a total frequency of 27.0%. Only...... one case (1.4%) of methicillin-resistance was registered. Coagulase-negative staphylococci (CoNS) were frequent, sole pathogen in 65 revisions and in polymicrobial cultures in 28 revisions with a total frequency of 29.5%. A pre-operative knee aspiration was performed in 50% and preoperative blood...

30 CFR 285.617 - What activities require a revision to my SAP, and when will MMS approve the revision?

Science.gov (United States)

2010-07-01

... 30 Mineral Resources 2 2010-07-01 2010-07-01 false What activities require a revision to my SAP, and when will MMS approve the revision? 285.617 Section 285.617 Mineral Resources MINERALS MANAGEMENT...: (1) Designed not to cause undue harm or damage to natural resources; life (including human and...

Pain and Function Following Revision Cubital Tunnel Surgery.

Science.gov (United States)

Davidge, Kristen M; Ebersole, Gregory C; Mackinnon, Susan E

2017-11-01

The purpose of this study was to determine pain and functional outcomes following revision cubital tunnel surgery and to identify predictors of poor postoperative outcome. A retrospective cohort study was conducted of all patients undergoing revision cubital tunnel surgery over a 5-year period at a high-volume peripheral nerve center. Intraoperative findings, demographic and injury factors, and outcomes were reviewed. Average pain, worst pain, and impact of pain on self-perceived quality of life were each measured using a 10-cm visual analog scale (VAS). Function was evaluated using pinch and grip strength, as well as the Disabilities of the Arm, Shoulder and Hand (DASH) questionnaire. Differences in preoperative and postoperative pain, strength, and DASH were analyzed using nonparametric tests. Predictors of postoperative average pain were evaluated using odds ratios and linear regression analyses. The final cohort consisted of 50 patients (mean age: 46.3 ± 12.5 years; 29 [68%] male) undergoing 52 revision ulnar nerve transpositions (UNTs). Pain VAS scores decreased significantly following revision UNT. Strength and DASH scores demonstrated nonsignificant improvements postoperatively. Worse preoperative pain and greater than 1 prior cubital tunnel procedure were significant predictors of worse postoperative average pain VAS scores. Patients can and do improve following revision cubital tunnel surgery, particularly as it relates to pain. Intraoperative findings during the revision procedure suggest that adherence to specific principles in the primary operation is key to prevention of secondary cubital tunnel syndrome.

Malária no Estado do Amapá, Brasil, de 1970 a 2003: trajetória e controle Malaria in Amapá State, Brazil, 1970-2003: background and control

Directory of Open Access Journals (Sweden)

Rosilene Ferreira Cardoso

2007-06-01

Full Text Available O presente estudo tem por objetivo dimensionar a ocorrência de malária no Estado do Amapá, Brasil, no período de 1970 a 2003. Com dados de lâminas positivas, obtidos junto a agências de informações em saúde, foi construída uma série temporal de índice parasitário anual (IPA, por mil habitantes, considerando as informações de população obtidas junto ao Instituto Brasileiro de Geografia e Estatística. No contexto de um intenso incremento populacional, associado ao desenvolvimento regional, os resultados evidenciaram um aumento no período - não linear - dos valores de IPA, que passaram de 15,1‰, em 1970, para 74‰ no ano 2000. No reverso desse movimento, em meio aos esforços de controle da doença, observa-se uma queda desses valores a partir de 2001, que alcança a ordem prevista de 50% em 2002. Acompanhando o movimento de incidência parasitária anual da malária na Amazônia, esses resultados apontaram para o aumento dos valores do IPA no período de 1970 a 2000, observando-se uma redução nos anos subseqüentes, cumprindo com as metas estabelecidas sob o programa vigente de controle da malária no Estado.The present study aims to describe malaria occurrence from 1970 to 2003 in the State of Amapá, Brazil. With positive films obtained from health agencies, temporal series on the annual parasite incidence - API (per 1,000 inhabitants were elaborated, taking into account population data available from the Brazilian Institute of Geography and Statistics. The results showed an increase in API values, although non-linear, related to the rapid population growth associated with regional economic and social development during the period, ranging from 15.1‰ in 1970 to 74.0‰ in 2000. Reversing this trend, a decrease appeared from 2001 onward, reaching a reduction of 50% in 2002. The results showed an increase in API values from 1970 to 2000, consistent with the incidence profile for malaria occurrence in the Amazon. A

Revision hip preservation surgery with hip arthroscopy: clinical outcomes.

Science.gov (United States)

Domb, Benjamin G; Stake, Christine E; Lindner, Dror; El-Bitar, Youseff; Jackson, Timothy J

2014-05-01

To analyze and report the clinical outcomes of a cohort of patients who underwent revision hip preservation with arthroscopy and determine predictors of positive and negative outcomes. During the study period from April 2008 to December 2010, all patients who underwent revision hip preservation with arthroscopy were included. This included patients who had previous open surgery and underwent revision with arthroscopy. Patient-reported outcome (PRO) scores were obtained preoperatively and at 3-month, 1-year, 2-year, and 3-year follow-up time points. Any revision surgeries and conversions to total hip arthroplasty were noted. A multiple regression analysis was performed to look for positive and negative predictive factors for improvement in PROs after revision hip arthroscopy. Forty-seven hips in 43 patients had completed 2 years' follow-up or needed total hip arthroplasty. The mean length of follow-up was 29 months (range, 24 to 47 months). Of the hips, 31 (66%) had either unaddressed or incompletely treated femoroacetabular impingement. There was a significant improvement in all PRO scores at a mean of 29 months after revision (P arthroscopy can achieve moderately successful outcomes and remains a viable treatment strategy after failed primary hip preservation surgery. Preoperative predictors of success after revision hip arthroscopy include segmental labral defects, unaddressed or incompletely addressed femoroacetabular impingement, heterotopic ossification, and previous open surgery. Level IV, therapeutic case series. Copyright © 2014 Arthroscopy Association of North America. Published by Elsevier Inc. All rights reserved.

HEDR modeling approach: Revision 1

International Nuclear Information System (INIS)

Shipler, D.B.; Napier, B.A.

1994-05-01

This report is a revision of the previous Hanford Environmental Dose Reconstruction (HEDR) Project modeling approach report. This revised report describes the methods used in performing scoping studies and estimating final radiation doses to real and representative individuals who lived in the vicinity of the Hanford Site. The scoping studies and dose estimates pertain to various environmental pathways during various periods of time. The original report discussed the concepts under consideration in 1991. The methods for estimating dose have been refined as understanding of existing data, the scope of pathways, and the magnitudes of dose estimates were evaluated through scoping studies

A reliability analysis of the revised competitiveness index.

Science.gov (United States)

Harris, Paul B; Houston, John M

2010-06-01

This study examined the reliability of the Revised Competitiveness Index by investigating the test-retest reliability, interitem reliability, and factor structure of the measure based on a sample of 280 undergraduates (200 women, 80 men) ranging in age from 18 to 28 years (M = 20.1, SD = 2.1). The findings indicate that the Revised Competitiveness Index has high test-retest reliability, high inter-item reliability, and a stable factor structure. The results support the assertion that the Revised Competitiveness Index assesses competitiveness as a stable trait rather than a dynamic state.

Praxis teaching in the ambit of learning assessment of endodontics in a Chilean university.

Science.gov (United States)

Sánchez-Sanhueza, Gabriela; Cisterna Cabrera, Francisco

2015-01-01

The practice of assessing must ensure that the outcome of the process be a reflection of the learning achieved by students. The aim of this study was to describe the essential attributes of the praxis teacher in the area of Endodontics Learning Evaluation, in the School of Dentistry at the Universidad de Concepción, Chile. This study is designed to diagnose the reliability and objectivity of assessing the learning process, as a framework for innovation, and with a focus on evaluating endodontics skills. This hermeneutic study has a qualitative methodology. It was based on in-depth semi-structured interviews applied to 14 students and 5 teachers, and two focus groups consisting of eight students each. When the study was conducted, the research findings indicated that the evaluation process was not objective and lacked established criteria, and especially a guide to determining the skills. The theoretical evaluation was only summative. The formative role was not formally established. The subjects answered mostly psychometric instruments by multiple choice and with short or extended answers. It was concluded that teacher practice held meaning only if it was backed by academic expertise in the area of endodontics, according to no clear criteria or validated instruments. On the other hand, the groundwork was in place for using an epistemological style in endodontics. This provided a basis for the actual improvements, and allowed the tools developed to be dialectically interconnected with teacher experience. A quantitative analysis was not considered, but could be supplemented later to enhance the data analysis in a future study.

Descriptive epidemiology of the Multicenter ACL Revision Study (MARS) cohort.

Science.gov (United States)

Wright, Rick W; Huston, Laura J; Spindler, Kurt P; Dunn, Warren R; Haas, Amanda K; Allen, Christina R; Cooper, Daniel E; DeBerardino, Thomas M; Lantz, Brett Brick A; Mann, Barton J; Stuart, Michael J

2010-10-01

Revision anterior cruciate ligament (ACL) reconstruction has worse outcomes than primary reconstructions. Predictors for these worse outcomes are not known. The Multicenter ACL Revision Study (MARS) Group was developed to perform a multisurgeon, multicenter prospective longitudinal study to obtain sufficient subjects to allow multivariable analysis to determine predictors of clinical outcome. To describe the formation of MARS and provide descriptive analysis of patient demographics and clinical features for the initial 460 enrolled patients to date in this prospective cohort. Cross-sectional study; Level of evidence, 2. After training and institutional review board approval, surgeons began enrolling patients undergoing revision ACL reconstruction, recording patient demographics, previous ACL reconstruction methods, intra-articular injuries, and current revision techniques. Enrolled subjects completed a questionnaire consisting of validated patient-based outcome measures. As of April 1, 2009, 87 surgeons have enrolled a total of 460 patients (57% men; median age, 26 years). For 89%, the reconstruction was the first revision. Mode of failure as deemed by the revising surgeon was traumatic (32%), technical (24%), biologic (7%), combination (37%), infection (MARS Group has been able to quickly accumulate the largest revision ACL reconstruction cohort reported to date. Traumatic reinjury is deemed by surgeons to be the most common single mode of failure, but a combination of factors represents the most common mode of failure. Allograft graft choice is more common in the revision setting than autograft. Concomitant knee injury is extremely common in this population.

Early childhood growth and cognitive outcomes: Findings from the MAL-ED study.

Science.gov (United States)

Scharf, Rebecca J; Rogawski, Elizabeth T; Murray-Kolb, Laura E; Maphula, Angelina; Svensen, Erling; Tofail, Fahmida; Rasheed, Muneera; Abreu, Claudia; Vasquez, Angel Orbe; Shrestha, Rita; Pendergast, Laura; Mduma, Estomih; Koshy, Beena; Conaway, Mark R; Platts-Mills, James A; Guerrant, Richard L; DeBoer, Mark D

2018-02-02

Although many studies around the world hope to measure or improve developmental progress in children to promote community flourishing and productivity, growth is sometimes used as a surrogate because cognitive skills are more difficult to measure. Our objective was to assess how childhood measures of anthropometry correlate with measures of child development in low-income settings with high prevalence of poor nutrition and enteric disease, to inform studies considering growth outcomes in the absence of direct child developmental skill assessment. Children from the MAL-ED study were followed from birth to 24 months of age in field sites in 8 low- and middle-income countries across 3 continents. Monthly weight, length, and head circumference measurements were performed. At 24 months, the Bayley Scales of Infant and Toddler Development was administered. We correlated cognitive measures at 24 months with anthropometric measurements from birth to 2 years comparing 3 constructs: absolute attained monthly measures, summative difference in measures from the mean growth curve, and rate of change in measures. Growth faltering at multiple time periods is related to Bayley cognitive outcomes at 24 months. Birthweight, overall growth by 18-24 months, and rate of growth in the 6- to 18-month period were most associated with 24-month developmental scores. In this study, head circumference measurements, compared with length, was more closely linked to cognitive scores at 24 months. Notably, all studies between growth and cognitive outcomes exhibited low r 2 values (0.001-0.049). Anthropometric measures, particularly head circumference, were related to cognitive development, although explaining a low percent of variance. When feasible, direct measures of child development may be more useful. © 2018 John Wiley & Sons Ltd.

Social, societal, and economic burden of mal de debarquement syndrome.

Science.gov (United States)

Macke, Allison; LePorte, Andrew; Clark, Brian C

2012-07-01

Mal de debarquement syndrome (MdDS) is a disorder of phantom perception of self-motion of unknown cause. The purpose of this work was to describe the quality of life (QOL) of patients with MdDS and to estimate the economic costs associated with this disorder. A modified version of a QOL survey used for another neurological disease (multiple sclerosis; MSQOL-54) was used to assess the impact of MdDS on QOL in 101 patients. The estimated economic costs were based on self-reported direct and indirect costs of individuals living in the United States using Medicare reimbursement payment rates for 2011 in 79 patients. Patients with MdDS reported a poor overall QOL as indicated by a mean composite QOL score of 59.26 ± 1.89 (out of 100). The subcategories having the lowest QOL rating were role limitations due to physical problems (18.32 ± 3.20), energy (34.24 ± 1.47), and emotional problems (36.30 ± 4.00). The overall physical health composite score including balance was 49.40 ± 1.69, and the overall mental health composite score was 52.40 ± 1.83. The cost to obtain a diagnosis was $2,997 ± 337, which included requiring an average of 19 physician visits per patient. The direct cost of MdDS medical care was $826 ± 140 per patient per year, which mainly included diagnostic imaging and physician visits. The indirect costs (i.e., lost wages) were $9,781 ± 2,347 per patient per year. Among 65 patients who were gainfully employed when they acquired MdDS, the indirect costs were $11,888 ± 2,786 per patient per year. Thus, the total annual cost of the disorder ranged from $11,493 ± 2,341 to $13,561 ± 2,778 per patient per year depending on employment status prior to developing MdDS. MdDS negatively and dramatically impacts QOL, and also imposes a substantial economic burden on MdDS patients. These findings underscore the need for further basic and clinical research on MdDS.

Letter of Map Revision

Data.gov (United States)

Earth Data Analysis Center, University of New Mexico — The National Flood Hazard Layer (NFHL) data incorporates all Digital Flood Insurance Rate Map(DFIRM) databases published by FEMA, and any Letters Of Map Revision...

Revision without ordinals

NARCIS (Netherlands)

Rivello, Edoardo

2013-01-01

We show that Herzberger’s and Gupta’s revision theories of truth can be recast in purely inductive terms, without any appeal neither to the transfinite ordinal numbers nor to the axiom of Choice. The result is presented in an abstract and general setting, emphasising both its validity for a wide

Partially overlapping sensorimotor networks underlie speech praxis and verbal short-term memory: evidence from apraxia of speech following acute stroke.

Science.gov (United States)

Hickok, Gregory; Rogalsky, Corianne; Chen, Rong; Herskovits, Edward H; Townsley, Sarah; Hillis, Argye E

2014-01-01

We tested the hypothesis that motor planning and programming of speech articulation and verbal short-term memory (vSTM) depend on partially overlapping networks of neural regions. We evaluated this proposal by testing 76 individuals with acute ischemic stroke for impairment in motor planning of speech articulation (apraxia of speech, AOS) and vSTM in the first day of stroke, before the opportunity for recovery or reorganization of structure-function relationships. We also evaluated areas of both infarct and low blood flow that might have contributed to AOS or impaired vSTM in each person. We found that AOS was associated with tissue dysfunction in motor-related areas (posterior primary motor cortex, pars opercularis; premotor cortex, insula) and sensory-related areas (primary somatosensory cortex, secondary somatosensory cortex, parietal operculum/auditory cortex); while impaired vSTM was associated with primarily motor-related areas (pars opercularis and pars triangularis, premotor cortex, and primary motor cortex). These results are consistent with the hypothesis, also supported by functional imaging data, that both speech praxis and vSTM rely on partially overlapping networks of brain regions.

Hickam AFB, Hawaii Revised Uniform Summary of Surface Weather Observations (RUSSWO). Parts A-F.

Science.gov (United States)

1985-04-01

ZkAN~,I EATV A. TO RELATIVE HUMIDITY -- EAT’E~SE; VIC /MAL I.I 2n 4CK A A F H---- 74-337 STATION STATION NAME PERIOD CUMULATIVE PERCENTAGE FREQUENCY...AL 1 li 9 o G l O 1 0 . 1; 99 .9 7 92 -6 71.2 4 1’_.1 l S 1 67 . 72 2- ] USAFETAC F 0.87-5 (OL A) ....... -LCAIAL CL!’"ATCL3Y -sRANCM EATV - c L r TAC

Smoking is associated with earlier time to revision of total knee arthroplasty.

Science.gov (United States)

Lim, Chin Tat; Goodman, Stuart B; Huddleston, James I; Harris, Alex H S; Bhowmick, Subhrojyoti; Maloney, William J; Amanatullah, Derek F

2017-10-01

Smoking is associated with early postoperative complications, increased length of hospital stay, and an increased risk of revision after total knee arthroplasty (TKA). However, the effect of smoking on time to revision TKA is unknown. A total of 619 primary TKAs referred to an academic tertiary center for revision TKA were retrospectively stratified according to the patient smoking status. Smoking status was then analyzed for associations with time to revision TKA using a Chi square test. The association was also analyzed according to the indication for revision TKA. Smokers (37/41, 90%) have an increased risk of earlier revision for any reason compared to non-smokers (274/357, 77%, p=0.031). Smokers (37/41, 90%) have an increased risk of earlier revision for any reason compared to ex-smokers (168/221, 76%, p=0.028). Subgroup analysis did not reveal a difference in indication for revision TKA (p>0.05). Smokers are at increased risk of earlier revision TKA when compared to non-smokers and ex-smokers. The risk for ex-smokers was similar to that of non-smokers. Smoking appears to have an all-or-none effect on earlier revision TKA as patients who smoked more did not have higher risk of early revision TKA. These results highlight the need for clinicians to urge patients not to begin smoking and encourage smokers to quit smoking prior to primary TKA. Copyright © 2017 Elsevier B.V. All rights reserved.

Hanford Site technical baseline database. Revision 1

International Nuclear Information System (INIS)

Porter, P.E.

1995-01-01

This report lists the Hanford specific files (Table 1) that make up the Hanford Site Technical Baseline Database. Table 2 includes the delta files that delineate the differences between this revision and revision 0 of the Hanford Site Technical Baseline Database. This information is being managed and maintained on the Hanford RDD-100 System, which uses the capabilities of RDD-100, a systems engineering software system of Ascent Logic Corporation (ALC). This revision of the Hanford Site Technical Baseline Database uses RDD-100 version 3.0.2.2 (see Table 3). Directories reflect those controlled by the Hanford RDD-100 System Administrator. Table 4 provides information regarding the platform. A cassette tape containing the Hanford Site Technical Baseline Database is available

Publishing and Revising Content

Science.gov (United States)

Editors and Webmasters can publish content without going through a workflow. Publishing times and dates can be set, and multiple pages can be published in bulk. Making an edit to published content created a revision.

Development and Psychometric Validation of the Family Outcomes Survey-Revised

Science.gov (United States)

Bailey, Donald B., Jr.; Raspa, Melissa; Olmsted, Murrey G.; Novak, Scott P.; Sam, Ann M.; Humphreys, Betsy P.; Nelson, Robin; Robinson, Nyle; Guillen, Chelsea

2011-01-01

Few psychometrically valid scales exist to assess family outcomes and the helpfulness of early intervention. This article describes the development and psychometric properties of the Family Outcomes Survey-Revised. The revision was prompted by the need to (a) create a new format that would be easier for parents to understand, (b) revise and expand…

Age and Early Revision After Primary Total Hip Arthroplasty for Osteoarthritis.

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Meyer, Zachary; Baca, Geneva; Rames, Richard; Barrack, Robert; Clohisy, John; Nam, Denis

2017-11-01

Prior reports have noted an increased risk of early revision among younger patients undergoing total hip arthroplasty (THA) but have been confounded by the inclusion of various diagnoses. The purpose of this study was to assess the revision rate and the time to revision for patients undergoing THA for osteoarthritis based on age. Patients with a diagnosis of osteoarthritis who underwent both primary and revision THA at the same institution were identified. The time between primary and revision surgery and the indication for revision were collected. Patients were stratified into 2 groups based on age at the time of primary THA: 64 years or younger (group 1) or 65 years or older (group 2). Between 1996 and 2016, a total of 4662 patients (5543 hips) underwent primary THA for a diagnosis of osteoarthritis. Of these, 100 patients (104 hips) received a revision THA (62 in group 1 and 42 in group 2). Mean age was 52.7±8.4 years in group 1 vs 73.4±6.3 years in group 2 (Pprimary to revision surgery was 3.0±3.2 years for group 1 and 1.1±2.1 years for group 2 (P=.001). Among patients undergoing primary THA for a diagnosis of osteoarthritis, younger age is not associated with an increased rate of early failure or revision. [Orthopedics. 2017; 40(6):e1069-e1073.]. Copyright 2017, SLACK Incorporated.

Revision washout decreases implant capsule tissue culture positivity: a multicenter study.

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Henry, Gerard D; Carson, Culley C; Wilson, Steven K; Wiygul, Jeremy; Tornehl, Chris; Cleves, Mario A; Simmons, Caroline J; Donatucci, Craig F

2008-01-01

Positive cultures, visible biofilm and confocal micrography confirm bacterial presence on clinically uninfected inflatable penile prostheses at revision surgery. Salvage irrigation has been proved to rescue patients with clinically infected inflatable penile prostheses. Similar washout at revision for noninfectious reasons significantly lowers subsequent infection rates. We investigated a larger series of patients for positive culture rates and evaluated implant capsule tissue culture rates before and after revision washout. At 4 institutions a total of 148 patients with inflatable penile prostheses underwent revision surgery for noninfectious reasons between June 2001 and September 2005. Swab cultures of the fluid around the pump and visible biofilm were obtained. Also, in 65 patients a wedge of tissue from the capsule that forms around the pump was cultured. After implant removal revision washout of the implant spaces was performed and a second wedge of tissue was cultured. Of the 148 patients 97 (66%) had positive bacterial swab cultures of the fluid around the pump or biofilm. A total of 124 isolates were cultured. Of the 65 implant capsule tissue cultures obtained before washout 28 (43%) were positive for bacteria, while 16 (25%) obtained after revision washout were positive. Positive cultures and visible bacterial biofilm are present on clinically uninfected inflatable penile prostheses at revision surgery in most patients. Revision washout appears to decrease the bacterial load on implant capsule tissue at revision surgery of inflatable penile prostheses for noninfectious reasons.

Psicoterapia v/s Farmacoterapia I. Aproximación inicial a las fronteras disciplinarias e ideológicas frente a una praxis compartida.

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Roberto Polanco C

2007-01-01

Full Text Available En el campo del tratamiento de los desordenes mentales existen hitos a lo largo de la historia moderna de la ciencia que sirven de referencia para poder entender el estado actual de dos importantes disciplinas cuyos campos disciplinarios se yuxtaponen. El objetivo de este artículo es aportar una primera reflexión sobre las formas de evaluar el campo de los desordenes mentales, se establece un especial énfasis crítico en el rol de la academia como ente formador y reproductor de estos grupos disciplinarios, además se introduce el debate sobre el papel de los psicólogos clínicos frente al uso de psicofármacos, proponiendo un debate que supere la reproducción de ciertos campos ideológicos que se traducen en “trincheras disciplinarias” las cuales se enfrentan al momento de establecer la praxis clínica en el campo social.

High proximal migration in cemented acetabular revisions operated with bone impaction grafting; 47 revision cups followed with RSA for 17 years.

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Mohaddes, Maziar; Herberts, Peter; Malchau, Henrik; Johanson, Per-Erik; Kärrholm, Johan

2017-05-12

Bone impaction grafting is a biologically and mechanically appealing option in acetabular revision surgery, allowing restitution of the bone stock and restoration of the biomechanics. We analysed differences in proximal migration of the revision acetabular components when bone impaction grafting is used together with a cemented or an uncemented cup. 43 patients (47 hips), revised due to acetabular loosening and judged to have less than 50% host bone-implant contact were included. The hips were randomised to either an uncemented (n = 20) or a cemented (n = 27) revision cup. Radiostereometry and radiography was performed postoperatively, at 3 and 6 months, 1, 2, 3, 5, 7, 10 and 13 and 17 years postoperatively. Clinical follow-up was performed at 1, 2 and 5 years postoperatively and thereafter at the same interval as in the radiographic follow-up. There were no differences in the base line demographic data between the 2 groups. At the last follow-up (17 years) 14 hips (10 cemented, 4 uncemented) had been re-revised due to loosening. 3 additional cups (1 uncemented and 2 cemented) were radiographically loose. There was a higher early proximal migration in the cemented cups. Cups operated on with cement showed a higher early migration measured with RSA and also a higher number of late revisions. The reason for this is not known, but factors such as inclusion of cases with severe bone defects, use of smaller bone chips and issues related to the impaction technique might have had various degrees of influence.

RCBI-II: The Second Revision of the Revised Cyber Bullying Inventory

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Topcu, Çigdem; Erdur-Baker, Özgür

2018-01-01

The aim of this study is to update the Turkish version of the Revised Cyber Bullying Inventory (RCBI) and eliminate specific technology names. Validity and reliability tests were carried out with 1,803 high school students. The updated version of the RCBI yields valid and reliable scores measuring cyberbullying and victimization.

Methods for implementing revisions to emergency operating procedures. Final report

International Nuclear Information System (INIS)

Myers, L.B.; Bell, A.J.

1984-05-01

In response to the Three Mile Island (TMI) accident, the US Nuclear Regulatory Commission (NRC) has published the TMI Action Plan. The TMI Action Plan Item I.C.1 called for the upgrading of Emergency Operating Procedures (EOPs) at nuclear power plants. The program developed from this Action Plan item has resulted in utility efforts to: (1) revise EOPs; (2) train personnel in the use of the EOPs; and (3) implement the revised EOPs. The NRC supported the study presented in this report to identify factors which influence the effectiveness of training and implementation of revised EOPs. The NRC's major concern was the possible effects of negative transfer of training. The report includes a summary of existing methods for implementing revisions to procedures based on interviews of plant personnel, a review of the training literature applicable to the effect of previously learned procedures on the learning of and performance with revised procedures (i.e., negative transfer) and recommendations of methods and schedules for implementing revised EOPs. While the study found that the concern over negative transfer of training was not as great as anticipated, several recommendations were made. These include: (1) overtraining of operators to reduce the effect of observed negative transfer; and (2) implementation of the revised EOPs as soon as possible after training to minimize the time operators must rely upon the old EOPs after having been trained on the revised EOPs. The results of the study should be useful both to the utilities and the NRC in the development and review of EOP implementation programs

Postoperative pain outcomes after transvaginal mesh revision.

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Danford, Jill M; Osborn, David J; Reynolds, W Stuart; Biller, Daniel H; Dmochowski, Roger R

2015-01-01

Although the current literature discusses mesh complications including pain, as well as suggesting different techniques for removing mesh, there is little literature regarding pain outcomes after surgical removal or revision. The purpose of this study is to determine if surgical removal or revision of vaginal mesh improves patient's subjective complaints of pelvic pain associated with original placement of mesh. After obtaining approval from the Vanderbilt University Medical Center Institutional Review Board, a retrospective review of female patients with pain secondary to previous mesh placement who underwent excision or revision of vaginal mesh from January 2000 to August 2012 was performed. Patient age, relevant medical history including menopause status, previous hysterectomy, smoking status, and presence of diabetes, fibromyalgia, interstitial cystitis, and chronic pelvic pain, was obtained. Patients' postoperative pain complaints were assessed. Of the 481 patients who underwent surgery for mesh revision, removal or urethrolysis, 233 patients met our inclusion criteria. One hundred and sixty-nine patients (73 %) reported that their pain improved, 19 (8 %) reported that their pain worsened, and 45 (19 %) reported that their pain remained unchanged after surgery. Prior history of chronic pelvic pain was associated with increased risk of failure of the procedure to relieve pain (OR 0.28, 95 % CI 0.12-0.64, p = 0.003). Excision or revision of vaginal mesh appears to be effective in improving patients' pain symptoms most of the time. Patients with a history of chronic pelvic pain are at an increased risk of no improvement or of worsening pain.

[The Use of Jumbo Cups in Revision Total Hip Arthroplasty].

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von Roth, Philipp; Wassilew, Georgi I

2017-10-01

Extra-large uncemented jumbo cups are among the most common methods of acetabular revision. Jumbo cups do not contribute to bone stock restoration, and in the case of a subsequent revision, an even larger bone defect is to be expected. Thus, understanding long-term survival is essential. The present article discusses the literature relevant to this topic and addresses technical and implant-specific characteristics of jumbo cups. In summary, jumbo cups show an acceptable long-term survival rate, with aseptic loosening as the most common reason for revision and dislocation being the most common complication. Through the development of alternative revision systems, jumbo cups have lost their importance in today's practice. However, they can serve as a benchmark for studies of newer technologies in revision total hip arthroplasty. Georg Thieme Verlag KG Stuttgart · New York.

Cement-in-cement acetabular revision with a constrained tripolar component.

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Leonidou, Andreas; Pagkalos, Joseph; Luscombe, Jonathan

2012-02-17

Dislocation of a total hip replacement (THR) is common following total hip arthroplasty (THA). When nonoperative management fails to maintain reduction, revision surgery is considered. The use of constrained acetabular liners has been extensively described. Complete removal of the old cement mantle during revision THA can be challenging and is associated with significant complications. Cement-in-cement revision is an established technique. However, the available clinical and experimental studies focus on femoral stem revision. The purpose of this study was to present a case of cement-in-cement acetabular revision with a constrained component for recurrent dislocations and to investigate the current best evidence for this technique. This article describes the case of a 74-year-old woman who underwent revision of a Charnley THR for recurrent low-energy dislocations. A tripolar constrained acetabular component was cemented over the primary cement mantle following removal of the original liner by reaming, roughening the surface, and thoroughly irrigating and drying the primary cement. Clinical and radiological results were good, with the Oxford Hip Score improving from 11 preoperatively to 24 at 6 months postoperatively. The good short-term results of this case and the current clinical and biomechanical data encourage the use of the cement-in-cement technique for acetabular revision. Careful irrigation, drying, and roughening of the primary surface are necessary. Copyright 2012, SLACK Incorporated.

Single-stage Acetabular Revision During Two-stage THA Revision for Infection is Effective in Selected Patients.

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Fink, Bernd; Schlumberger, Michael; Oremek, Damian

2017-08-01

The treatment of periprosthetic infections of hip arthroplasties typically involves use of either a single- or two-stage (with implantation of a temporary spacer) revision surgery. In patients with severe acetabular bone deficiencies, either already present or after component removal, spacers cannot be safely implanted. In such hips where it is impossible to use spacers and yet a two-stage revision of the prosthetic stem is recommended, we have combined a two-stage revision of the stem with a single revision of the cup. To our knowledge, this approach has not been reported before. (1) What proportion of patients treated with single-stage acetabular reconstruction as part of a two-stage revision for an infected THA remain free from infection at 2 or more years? (2) What are the Harris hip scores after the first stage and at 2 years or more after the definitive reimplantation? Between June 2009 and June 2014, we treated all patients undergoing surgical treatment for an infected THA using a single-stage acetabular revision as part of a two-stage THA exchange if the acetabular defect classification was Paprosky Types 2B, 2C, 3A, 3B, or pelvic discontinuity and a two-stage procedure was preferred for the femur. The procedure included removal of all components, joint débridement, definitive acetabular reconstruction (with a cage to bridge the defect, and a cemented socket), and a temporary cemented femoral component at the first stage; the second stage consisted of repeat joint and femoral débridement and exchange of the femoral component to a cementless device. During the period noted, 35 patients met those definitions and were treated with this approach. No patients were lost to followup before 2 years; mean followup was 42 months (range, 24-84 months). The clinical evaluation was performed with the Harris hip scores and resolution of infection was assessed by the absence of clinical signs of infection and a C-reactive protein level less than 10 mg/L. All

14 CFR 152.323 - Budget revision: Airport development.

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2010-01-01

... 14 Aeronautics and Space 3 2010-01-01 2010-01-01 false Budget revision: Airport development. 152... TRANSPORTATION (CONTINUED) AIRPORTS AIRPORT AID PROGRAM Accounting and Reporting Requirements § 152.323 Budget... change in the budget estimates, the sponsor shall submit a request for budget revision on a form...

Pending revisions to ANS 56.8-81 containment systems leakage testing requirements

International Nuclear Information System (INIS)

Brown, T.M.

1986-01-01

The US Nuclear Regulatory Commission is currently processing a revision to Appendix J of Part 50, Title 10 of the Code of Federal Regulations. The revised Appendix J will not reference any ANSI standard. Processed concurrently with the revised Appendix J is a draft Regulatory Guide which does endorse ANS Standard 56.8. The draft Regulatory Guide currently takes many exceptions to the Standard. Many of the exceptions are changes the Working Group had in process and the exceptions are to bring the draft Regulatory Guide in line with the future Standard. The Working Group has completed their revisions to the Standard and its appendices. These revisions have been submitted to the Nuclear Power Plants Standards Committee (NUPPSCO). The NUPPSCO comments have recently been addressed by the Working Group and the Working Group response has been sent to the NUPPSCO commentators. This paper will discuss the revisions made to the Standard, the significance of the revisions and future tasks or Standard revisions which the ANS 56.8 Working Group may address

Comparing contemporary revision burden among hip and knee joint replacement registries

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Brian J. McGrory, MD, MS

2016-06-01

Conclusions: Revision burden has gradually decreased for hip replacements and has remained relatively constant for knee replacements both for the last 4 years and compared to historic controls. Knee revision burden was lower than hip revision burden for each period examined. Revision burden is one measure that may be helpful in following the effect of changes in surgical technique and implant design over time in registry populations and may be a helpful way to compare overall results between registries.

Revision Hip Arthroscopy Indications and Outcomes: A Systematic Review.

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Sardana, Vandit; Philippon, Marc J; de Sa, Darren; Bedi, Asheesh; Ye, Lily; Simunovic, Nicole; Ayeni, Olufemi R

2015-10-01

To identify the indications and outcomes in patients undergoing revision hip arthroscopy. The electronic databases Embase, Medline, HealthStar, and PubMed were searched from 1946 to July 19, 2014. Two blinded reviewers searched, screened, and evaluated the data quality of the studies using the Methodological Index for Non-Randomized Studies scale. Data were abstracted in duplicate. Agreement and descriptive statistics are presented. Six studies were included (3 prospective case series and 3 retrospective chart reviews), with a total of 448 hips examined. The most common indications for revision hip arthroscopy included residual femoroacetabular impingement (FAI), labral tears, and chondral lesions. The mean interval between revision arthroscopy and the index procedure was 25.6 months. Overall, the modified Harris Hip Score improved by a mean of 33.6% (19.3 points) from the baseline score at 1-year follow-up. In 14.6% of patients, further surgical procedures were required, including re-revision hip arthroscopy (8.0%), total hip replacement (5.6%), and hip resurfacing (1.0%). Female patients more commonly underwent revision hip arthroscopy (59.7%). The current evidence examined in this review supports revision hip arthroscopy as a successful intervention to improve functional outcomes (modified Harris Hip Score) and relieve pain in patients with residual symptoms after primary FAI surgery, although the outcomes are inferior when compared with a matched cohort of patients undergoing primary hip arthroscopy for FAI. The main indication for revision is a candidate who has symptoms due to residual cam- or pincer-type deformity that was either unaddressed or under-resected during the index operation. However, it is important to consider that the studies included in this review are of low-quality evidence. Surgeons should consider incorporating a minimum 2-year follow-up for individuals after index hip-preservation surgery because revisions tended to occur within this

Rhinoplasty for the multiply revised nose.

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Foda, Hossam M T

2005-01-01

To evaluate the problems encountered on revising a multiply operated nose and the methods used in correcting such problems. The study included 50 cases presenting for revision rhinoplasty after having had 2 or more previous rhinoplasties. An external rhinoplasty approach was used in all cases. Simultaneous septal surgery was done whenever indicated. All cases were followed for a mean period of 32 months (range, 1.5-8 years). Evaluation of the surgical result depended on clinical examination, comparison of pre- and postoperative photographs, and degree of patients' satisfaction with their aesthetic and functional outcome. Functionally, 68% suffered nasal obstruction that was mainly caused by septal deviations and nasal valve problems. Aesthetically, the most common deformities of the upper two thirds of the nose included pollybeak (64%), dorsal irregularities (54%), dorsal saddle (44%), and open roof deformity (42%), whereas the deformities of lower third included depressed tip (68%), tip contour irregularities (60%), and overrotated tip (42%). Nasal grafting was necessary in all cases; usually more than 1 type of graft was used in each case. Postoperatively, 79% of the patients, with preoperative nasal obstruction, reported improved breathing; 84% were satisfied with their aesthetic result; and only 8 cases (16%) requested further revision to correct minor deformities. Revision of a multiply operated nose is a complex and technically demanding task, yet, in a good percentage of cases, aesthetic as well as functional improvement are still possible.

The Effects of the Revised CPPNM on Legislative Framework

International Nuclear Information System (INIS)

Kwak, Sung-Woo; Yoo, Ho-Sik; Shim, Hye-Won; Chang, Sun-Young; Lee, Jong-Uk

2006-01-01

A Diplomatic Conference was held last July at Vienna of Austria and adopted an important Convention in physical protection field. The Convention is the revised Convention on Physical Protection of Nuclear Material. A State Party to the revised CPPNM has obligation to meet the Convention. Since the Amendment to CPPNM is expected to enter into force in near future, there is an urgent need to prepare for implementing the international obligation. Thus, it is important to assess the effect of the revised Convention on national legislative and regulatory framework to govern physical protection of domestic nuclear material and facilities. The objective of this paper is to perform comparative assessment between new provisions of the revised Convention and national law in order to prepare for the implementation of the international norm

Linfoma Nasal de Células T/Natural Killer Extranodal Refractario Mal Diagnosticado, Tratado de Manera Exitosa: Informe de Caso.

Science.gov (United States)

Saavedra Ramírez, José Domingo

2017-01-01

El linfoma de células T/natural killer extranodal ("extranodal natural killer/T-cell lymphoma", ENKL) nasal es un linfoma no Hodgkin (LNH) agresivo y poco común para el cual no se ha establecido un tratamiento de referencia claro, especialmente en el escenario de la enfermedad recidivante/refractaria. Debido a su rareza, no se han llevado a cabo ensayos aleatorizados específicamente en ENKL nasal; sin embargo, los informes de caso y las series de caso pequeñas ofrecen un conocimiento importante sobre nuevos tratamientos potenciales. Presentamos el informe de caso de un paciente con ENKL nasal (previamente mal diagnosticado como una sinusitis crónica recidivante) en quien la enfermedad progresó durante la quimioterapia con múltiples agentes pero respondió al tratamiento de segunda línea con pralatrexato como agente único. Analizamos opciones de tratamiento para el ENKL nasal recidivante/refractario y sugerimos que el pralatrexato se evalúe más a fondo en este escenario clínico.

NRC revision to 10 CFR Part 20

International Nuclear Information System (INIS)

Baker, R.E.; Cool, W.S.; Mills, W.A.

1983-01-01

The Nuclear Regulatory Commission's pollution standards have been revised since publication in the late 1950s, but the basic approach has not changed. The revisions resulted in inaccuracies, conflicts, and ambiguities in requirements. The need for comprehensive updating including radiation-protection principles, risk, occupational exposure dose limits, standards for the public (including de minimis level), surveys and monitoring, disposal into sewerage systems, and records is discussed. 2 tables

Draft revision of human factors guideline HF-010

International Nuclear Information System (INIS)

Lee, Hyun Chul; Lee, Yong Hee; Oh, In Seok; Lee, Jung Woon; Cha, Woo Chang; Lee, Dhong Ha

2003-05-01

The Application of Human Factors to the design of Man-Machine Interfaces System(MMIS) in the nuclear power plant is essential to the safety and productivity of the nuclear power plants, human factors standards and guidelines as well as human factors analysis methods and experiments are weightily used to the design application. A Korean engineering company has developed a human factors engineering guideline, so-call HF-010, and has used it for human factors design, however the revision of HF-010 is necessary owing to lack of the contents related to the advanced MMI(Man-Machine Interfaces). As the results of the reviews of HF-010, it is found out that the revision of Section 9. Computer Displays of HF-010 is urgent, thus the revision was drafted on the basis of integrated human factors design guidelines for VDT, human factors design guidelines for PMAS SPADES display, human factors design guidelines for PMAS alarm display, and human factors design guidelines for electronic displays developed by the surveillance and operation support project of KOICS. The draft revision of HF-010 Section 9 proposed in this report can be utilized for the human factors design of the advanced MMI, and the high practical usability of the draft can be kept up through the continuous revision according to the advancement of digital technology

Avaliação nutricional, produção e incidência do mal-do-panamá em bananeira 'Prata-Anã' (AAB adubada com K, no quarto ciclo

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José Tadeu Alves da Silva

2013-12-01

Full Text Available O presente trabalho teve como objetivos estimar a dose de K para obter a máxima eficiência física e econômica, estimar o nível crítico foliar de K e relacionar o equilíbrio nutricional da bananeira 'Prata-Anã' com a incidência de plantas com mal-do-panamá no 4º ciclo. O experimento foi realizado em Latossolo Vermelho-Amarelo (LVA, textura média, na região semiárida do norte de Minas Gerais, Brasil. Os tratamentos consistiram nas aplicações de quatro doses de K (0; 400; 800 e 1.200 kg ha-1 ano de K2O. Estes foram distribuídos em blocos ao acaso, com cinco repetições. A adubação com K promoveu aumento na produção da bananeira no 4º ciclo. A máxima eficiência física (31 Mg ha-1 e a econômica (30,5 Mg ha-1 foram obtidas com as aplicações de 969 e 707 kg ha-1 ano-1 de K2O, respectivamente. Os níveis críticos foliares de K obtidos foram 29,5 e 27,1 g kg-1, para a máxima eficiência física e econômica, respectivamente. O aumento das doses de K proporcionou melhor equilíbrio nutricional à bananeira e reduziu a porcentagem de plantas infestadas com o mal-do-panamá.

Le mal de Pott: à propos de 82 cas

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Badr Fedoul

2011-03-01

Full Text Available Nous rapportant dans cette étude, les résultats de l’expérience du service de neurochirurgie du CHU Hassan II de Fès dans la prise en charge du mal de pott dans la région de Fès. Il s’agit d’une étude rétrospective de quatre-vingt-deux cas; étalée sur une période de cinq ans (janvier 2002 au décembre 2006. L’objectif de ce travail était d’illustrer les différents aspects épidémiologiques, diagnostiques et thérapeutiques de la localisation vertébrale de la tuberculose dans notre pratique. L'âge moyen de nos patients était de 43,1 ans, avec une légère prédominance féminine (53,82%. La durée d'évolution de la maladie était longue (dix mois en moyenne; ceci est expliquée par la symptomatologie initiale insidieuse faite de rachialgies (98,78% et une admission des patients au stade de complications neurologiques (41,46%. La radiographie standard était réalisée chez tous nos patients, et complétée par la TDM dans 86.58% des cas ce qui a permis de déceler la prédominance de l'atteinte dorsale et lombaire. L'IRM est l'examen de choix, elle était demandée chez tous les malades déficitaires (37,8%.Tous nos patients ont bénéficié d'un traitement antibacillaire associé à une immobilisation du foyer pottique. Une décompression par voie antérieure était réalisée chez 29 patients (35,36 %; alors que la laminectomie n'était pratiquée que chez 5 patients (6.09 %, tandis que l'évacuation de l'abcès de psoas était réalisée chez 25 patients (30,48 %. Le diagnostic de certitude histologique était posé dans 51 cas (62,19%. Les meilleurs résultats étaient obtenus chez les malades opérés par voie antérieure, 26 cas (89,65% de récupération totale et 3 cas (10,34% partielle. L'évolution vers la consolidation et la fusion vertébrale était la règle chez tous nos malades et ceci au bout de 4 à 18 mois après le traitement.

Mal de Asclepio o Síndrome Judicial Médico

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Hernán Urbina Joiro

2015-12-01

Full Text Available

Se asocian crecientemente, de manera criminal, abogados, pacientes y médicos perversos contra médicos honestos, alineando el factor que peor puede degradar la medicina de hoy y potenciar sus otros males. Siendo dios de la medicina, el nacimiento y la muerte de Asclepio estuvieron marcados por la vileza, la que hoy amenaza de muerte a la profesión médica. Pero no hay que olvidar que finalmente Asclepio pudo ser resguardado de la perversidad.

No se trata de la situación de quien denuncia legítimamente una transgresión cometida por un médico. El Mal de Asclepio o Síndrome Judicial Médico describe la actuación calculada por auténticos «enfermos» —en el sentido sociopático—, con manifiesta intención de ocasionar daño a médicos inocentes, comúnmente a través de prácticas delictivas, ocasionando además males permanentes en la salud física y mental de quienes se habían esforzado, irónicamente, para sanar a los demás, en esta era de degradación de la profesión médica, en este momento extraño donde el bastón de Asclepio, dios de la medicina, fue cambiado por el caduceo de Mercurio, dios del comercio y también de los ladrones (1.

Asclepio fue un hijo no nacido, rescatado por un prodigio desde el vientre de su madre muerta y a punto de ser consumida por la pira funeraria. Coronis —o Corónide—, la madre, lo concibió tras un asalto del dios Apolo en la rivera de un río y, sin saber de su estado, cumplió con un pacto matrimonial arreglado por su padre, lo que incitó a Apolo a dar muerte a su joven esposo e impulsó a Artemisa, hermana de Apolo, a asesinar a flechazos a la propia Coronis. Fue el mismo Apolo quien, en el último momento, resolvió extraer del cadáver de Coronis al niño que puso por nombre Asclepio y que en adelante lucharía contra la muerte, incluso resucitando difuntos, hasta que la propia muerte —Hades— convenció de mala fe a Zeus, lo indujo al error —que más tarde

Effect of graft choice on the outcome of revision anterior cruciate ligament reconstruction in the Multicenter ACL Revision Study (MARS) Cohort

Science.gov (United States)

Wright, Rick W.; Huston, Laura J.; Haas, Amanda K.; Spindler, Kurt P.; Nwosu, Sam K.; Allen, Christina R.; Anderson, Allen F.; Cooper, Daniel E.; DeBerardino, Thomas M.; Dunn, Warren R.; Lantz, Brett (Brick) A.; Stuart, Michael J.; Garofoli, Elizabeth A.; Albright, John P.; Amendola, Annunziato (Ned); Andrish, Jack T.; Annunziata, Christopher C.; Arciero, Robert A.; Bach, Bernard R.; Baker, Champ L.; Bartolozzi, Arthur R.; Baumgarten, Keith M.; Bechler, Jeffery R.; Berg, Jeffrey H.; Bernas, Geoffrey A.; Brockmeier, Stephen F.; Brophy, Robert H.; Bush-Joseph, Charles A.; Butler, J. Brad; Campbell, John D.; Carey, James L.; Carpenter, James E.; Cole, Brian J.; Cooper, Jonathan M.; Cox, Charles L.; Creighton, R. Alexander; Dahm, Diane L.; David, Tal S.; Flanigan, David C.; Frederick, Robert W.; Ganley, Theodore J.; Gatt, Charles J.; Gecha, Steven R.; Giffin, James Robert; Hame, Sharon L.; Hannafin, Jo A.; Harner, Christopher D.; Harris, Norman Lindsay; Hechtman, Keith S.; Hershman, Elliott B.; Hoellrich, Rudolf G.; Hosea, Timothy M.; Johnson, David C.; Johnson, Timothy S.; Jones, Morgan H.; Kaeding, Christopher C.; Kamath, Ganesh V.; Klootwyk, Thomas E.; Levy, Bruce A.; Ma, C. Benjamin; Maiers, G. Peter; Marx, Robert G.; Matava, Matthew J.; Mathien, Gregory M.; McAllister, David R.; McCarty, Eric C.; McCormack, Robert G.; Miller, Bruce S.; Nissen, Carl W.; O'Neill, Daniel F.; Owens, Brett D.; Parker, Richard D.; Purnell, Mark L.; Ramappa, Arun J.; Rauh, Michael A.; Rettig, Arthur C.; Sekiya, Jon K.; Shea, Kevin G.; Sherman, Orrin H.; Slauterbeck, James R.; Smith, Matthew V.; Spang, Jeffrey T.; Svoboda, Steven J.; Taft, Timothy N.; Tenuta, Joachim J.; Tingstad, Edwin M.; Vidal, Armando F.; Viskontas, Darius G.; White, Richard A.; Williams, James S.; Wolcott, Michelle L.; Wolf, Brian R.; York, James J.

2015-01-01

Background Most surgeons believe that graft choice for ACL reconstruction is an important factor related to outcome. Although graft choice may be limited in the revision setting based on previously used grafts, it is still felt to be important. Hypothesis The purpose of this study was to determine if revision ACL graft choice predicts outcomes related to sports function, activity level, OA symptoms, graft re-rupture, and reoperation at two years following revision reconstruction. We hypothesized that autograft use would result in increased sports function, increased activity level, and decreased OA symptoms (as measured by validated patient reported outcome instruments). Additionally, we hypothesized that autograft use would result in decreased graft failure and reoperation rate 2 years following revision ACL reconstruction. Study Design Prospective cohort study; Level of evidence, 2. Methods Revision ACL reconstruction patients were identified and prospectively enrolled by 83 surgeons over 52 sites. Data collected included baseline demographics, surgical technique and pathology, and a series of validated patient reported outcome instruments (IKDC, KOOS, WOMAC, and Marx activity rating score). Patients were followed up at 2 years, and asked to complete the identical set of outcome instruments. Incidence of additional surgery and reoperation due to graft failure were also recorded. Multivariate regression models were used to determine the predictors (risk factors) of IKDC, KOOS, WOMAC, Marx scores, graft re-rupture, and reoperation rate at 2 years following revision surgery. Results 1205 patients were successfully enrolled with 697 (58%) males. Median age was 26. In 88% this was their first revision. 341 (28%) were undergoing revision by the surgeon that had performed the previous reconstruction. 583 (48%) underwent revision reconstruction utilizing an autograft, 590 (49%) allograft, and 32 (3%) both autograft and allograft. Median time since their last ACL

9 CFR 108.6 - Revision of plot plans, blueprints, and legends.

Science.gov (United States)

2010-01-01

... 9 Animals and Animal Products 1 2010-01-01 2010-01-01 false Revision of plot plans, blueprints... FACILITY REQUIREMENTS FOR LICENSED ESTABLISHMENTS § 108.6 Revision of plot plans, blueprints, and legends... changes affecting the workflow are to be made. The licensee shall: (a) Prepare revised plot plans...

Poorer survival after a primary implant during revision total knee arthroplasty

NARCIS (Netherlands)

Meijer, Marrigje F.; Reininga, Inge H. F.; Boerboom, Alexander L.; Stevens, Martin; Bulstra, Sjoerd K.

Revision total knee arthroplasty (rTKA) is a complex procedure. Depending on the degree of ligament and bone damage, either primary or revision implants are used. The purpose of this study was to compare survival rates of primary implants with revision implants when used during rTKA. A retrospective

Malária em usuários de drogas de administração endovenosa associada à soropositividade para HIV The association of malaria, HIV seropositivity and intravenous administration in drug users

Directory of Open Access Journals (Sweden)

Shin Shiang Lo

1991-02-01

Full Text Available Infecções induzidas de malária têm sido verificadas nos últimos anos no Estado de São Paulo, Brasil concomitantemente com o aumento de casos importados procedentes da região endêmica do país. Destaca-se o registro de um caso em 1988 e onze casos em 1989 de malária induzida por Plasmodium vivax, em indivíduos residentes na cidade de Presidente Prudente, situada a oeste do Estado e considerada uma das "portas de entrada" de pessoas procedentes da Região Amazônica. Os pacientes afirmaram não terem se deslocado recentemente ou negaram deslocamentos para áreas com possibilidade de transmissão de malária. Todos fizeram uso de drogas injetáveis, participando de círculos de conhecidos afins e geralmente dividiam a mesma agulha e seringa no uso da cocaína. Foi detectado o doente de malária que transmitiu inicialmente a doença ao caso de 1988, e a um primeiro grupo de três indivíduos em 1989. Destes três casos, um transmitiu a doença a outro grupo de dois indivíduos em 1989. A partir destas primeiras infecções e do uso continuado das drogas injetáveis entre grupos, surgiram dois novos casos e houve reinfecção em dois indivíduos (um destes apresentou duas reinfecções. O exame para detecção de HIV foi positivo em cinco indivíduos, um apresentou resultado negativo e não foi realizado em outros três indivíduos. São analisadas as informações desses casos e discutida a importância de sua ocorrência no momento atual.Cases of induced malaria have been notified in S. Paulo State, Brazil, in recent years. At the same time the number of cases imported from endemic regions of Brazil has been increasing. One case of induced malaria by Plasmodium vivax was registered in Presidente Prudente, located in the west of the State, in 1988 and a further eleven cases in 1989. This city is considered to be one of the main transit ports for people who come into the State from the Amazonian region. The patients declared that they had

Malária em grávidas de uma maternidade pública de Rio Branco (Acre, Brasil Malaria in pregnant women of a public maternity of Rio Branco (Acre State, Brazil

Directory of Open Access Journals (Sweden)

Regina Jarude

2003-04-01

Full Text Available OBJETIVO: descrever a freqüência dos achados clínico-laboratoriais em grávidas portadoras de malária. MÉTODOS: foi realizado estudo descritivo, série de casos, de 445 grávidas da Maternidade e Clínica de Mulheres Bárbara Heliodora (Rio Branco, Acre, do período de janeiro de 1996 a dezembro de 2001, com diagnóstico parasitológico de malária. Foram revistos os prontuários do período e selecionados os casos portadores de malária. RESULTADOS: no total de pacientes (n=33.420 internadas no período, estavam incluídas 445 (1,4% grávidas. Entre essas, a freqüência da infecção por Plasmodium vivax foi de 52,8% (n=235, por P. falciparum, de 43,8% (n=195, e 3,4% (n=15 por ambos os plasmódios. As alterações clínico-laboratoriais mais freqüentes (pPURPOSE: to describe the frequency of clinical and laboratorial findings in pregnant women with malaria. METHODS: a descriptive study was performed including 445 pregnant women with a positive diagnosis of malaria of the Maternity and women's Clinic Bárbara Heliodora (Rio Branco, Acre State, from January 1996 to December 2001. These cases were reviewed and the pregant women with malaria were selected. RESULTS: a total of 33,420 patients were hospitalized in that period. Of these, 445 pregnant women (1.4% were included. Among these, the frequency of the infection with Plasmodium vivax was 52.8% (n=235, with P. falciparum, 43.8% (n=195, and 3.4% (n=15 with both plasmodia. The most frequent clinical and laboratorial alterations (p<0.05 were observed in the patients with P. falciparum: pale mucosa, jaundice hemoglobin and hematocrit decrease, hypoglycemia and increase in serum aminotransferase, urea, creatinine and in bilirubin levels. Only one patient (1/445, a pregnant woman infected with P. falciparum died. Abortions, premature birth and low birth weight were detected in 1.3, 1.1 and 1.1% of the cases, respectively. CONCLUSIONS: these findings reflect the repercussion of malaria during

Revision of Pachycentria (Melastomataceae)

NARCIS (Netherlands)

Clausing, Gudrun

2000-01-01

A revision of Pachycentria Blume, which includes the monotypic Pogonanthera Blume, is presented. Pachycentria comprises eight species and one subspecies. Two species, P. vogelkopensis and P. hanseniana, are newly described. The genus is distinguished from other genera in the Medinillinae by a small

Revised accident source terms for light-water reactors

Energy Technology Data Exchange (ETDEWEB)

Soffer, L. [Nuclear Regulatory Commission, Washington, DC (United States)

1995-02-01

This paper presents revised accident source terms for light-water reactors incorporating the severe accident research insights gained in this area over the last 15 years. Current LWR reactor accident source terms used for licensing date from 1962 and are contained in Regulatory Guides 1.3 and 1.4. These specify that 100% of the core inventory of noble gases and 25% of the iodine fission products are assumed to be instantaneously available for release from the containment. The chemical form of the iodine fission products is also assumed to be predominantly elemental iodine. These assumptions have strongly affected present nuclear air cleaning requirements by emphasizing rapid actuation of spray systems and filtration systems optimized to retain elemental iodine. A proposed revision of reactor accident source terms and some im implications for nuclear air cleaning requirements was presented at the 22nd DOE/NRC Nuclear Air Cleaning Conference. A draft report was issued by the NRC for comment in July 1992. Extensive comments were received, with the most significant comments involving (a) release fractions for both volatile and non-volatile species in the early in-vessel release phase, (b) gap release fractions of the noble gases, iodine and cesium, and (c) the timing and duration for the release phases. The final source term report is expected to be issued in late 1994. Although the revised source terms are intended primarily for future plants, current nuclear power plants may request use of revised accident source term insights as well in licensing. This paper emphasizes additional information obtained since the 22nd Conference, including studies on fission product removal mechanisms, results obtained from improved severe accident code calculations and resolution of major comments, and their impact upon the revised accident source terms. Revised accident source terms for both BWRS and PWRS are presented.

O desafio da malária: o caso brasileiro e o que se pode esperar dos progressos da era genômica The malaria challenge: the Brazilian case and what can be expected from progress in genomics

Directory of Open Access Journals (Sweden)

Luiz Hildebrando Pereira da Silva

2002-01-01

Full Text Available A área endêmica de malária no Brasil se estende atualmente à totalidade da região amazônica, com cerca de 500 mil casos anuais, em geral com situações de baixa e média endemicidade mas ainda apresentando focos de alto risco. Fatores demográficos e socioeconômicos são dominantes nos desafios que enfrentam os Serviços de Saúde Pública no controle da malária. No presente artigo são discutidos fatores determinantes da instabilidade da situação endêmica bem como a necessidade de ações permanentes de vigilância e de intervenção dos Serviços de Saúde para que se evitem surtos epidêmicos e alastramento das áreas endêmicas. No artigo, em seguida, apresenta-se uma síntese de progressos recentes nos estudos da era genômica e pós-genômica sobre o parasita, o vetor e o hospedeiro humano que podem favorecer, no futuro, o desenvolvimento e a melhoria dos métodos de controle da malária.Malaria endemic areas in Brazil are restricted to the Amazon Region, with an average of 500 thousand new cases every year. The situation can be defined as unstable hipoendemic with, however, foci of high endemicity. Demographic and socio economic factors are main determinants in the malaria challenge for the Public Health System. In the present paper, biological and social factors responsible for the unstable endemic situation are discussed. The need for a permanent surveillance and intervention of Public Health Services are stressed to avoid the occurrence of local epidemics and spreading of endemic areas. In the paper, are also summarised recent lines of research developed in the post genomic era in the studies of parasite, vector and human molecular genetics that would favour the development, in the future, of new tools and procedures for malaria control

Comparison of mode of failure between primary and revision total knee arthroplasties.

Science.gov (United States)

Liang, H; Bae, J K; Park, C H; Kim, K I; Bae, D K; Song, S J

2018-04-01

Cognizance of common reasons for failure in primary and revision TKA, together with their time course, facilitates prevention. However, there have been few reports specifically comparing modes of failure for primary vs. revision TKA using a single prosthesis. The goal of the study was to compare the survival rates, modes of failure, and time periods associated with each mode of failure, of primary vs. revision TKA. The survival rates, modes of failure, time period for each mode of failure, and risk factors would differ between primary and revision TKA. Data from a consecutive cohort comprising 1606 knees (1174 patients) of primary TKA patients, and 258 knees (224 patients) of revision TKA patients, in all of whom surgery involved a P.F.C ® prosthesis (Depuy, Johnson & Johnson, Warsaw, IN), was retrospectively reviewed. The mean follow-up periods of primary and revision TKAs were 9.2 and 9.8 years, respectively. The average 10- and 15-year survival rates for primary TKA were 96.7% (CI 95%,±0.7%) and 85.4% (CI 95%,±2.0%), and for revision TKA 91.4% (CI 95%,±2.5%) and 80.5% (CI 95%,±4.5%). Common modes of failure included polyethylene wear, loosening, and infection. The most common mode of failure was polyethylene wear in primary TKA, and infection in revision TKA. The mean periods (i.e., latencies) of polyethylene wear and loosening did not differ between primary and revision TKAs, but the mean period of infection was significantly longer for revision TKA (1.2 vs. 4.8 years, P=0.003). Survival rates decreased with time, particularly more than 10 years post-surgery, for both primary and revision TKAs. Continuous efforts are required to prevent and detect the various modes of failure during long-term follow-up. Greater attention is necessary to detect late infection-induced failure following revision TKA. Case-control study, Level III. Copyright © 2017 Elsevier Masson SAS. All rights reserved.

A democracia no Brasil não é um mal-entendido = Democracy in Brazil is not a misunderstanding

Directory of Open Access Journals (Sweden)

Coelho, Maria Francisca Pinheiro

2014-01-01

Full Text Available A ideia deste trabalho surgiu da famosa frase de Sérgio Buarque de Holanda, em Raízes do Brasil: “A democracia no Brasil foi sempre um lamentável mal-entendido. ” Para o autor, inspirado nos tipos ideais weberianos e sob um olhar comparativo, o Brasil com seu homem cordial – aquele que age mais pelo coração do que pela razão – e com o predomínio do espaço privado sobre o público não se apresentava como um solo receptivo aos valores de igualdade da democracia. O texto pretende sugerir que a institucionalização das regras do jogo democrático relativiza o peso da cultura, sem, contudo, alterar seus traços no ritmo compatível com as mudanças das normas. O Brasil, com todos os problemas decorrentes de uma sociedade desigual e hierárquica, situa-se atualmente entre as democracias mais consolidadas da América Latina, que mais interagem e que apresentam disposição para o diálogo

Revised accident source terms and control room habitability

International Nuclear Information System (INIS)

Lahti, G.P.; Hubner, R.S.; Johnson, W.J.; Schwartz, B.C.

1993-01-01

In April 1992, the NRC staff presented to the Commissioners the draft NUREG open-quotes Revised Accident Source Terms for Light-Water Nuclear Power Plants.close quotes This document is the culmination of more than ten years of NRC-sponsored research and represents the first change in the NRC's position on source terms since TID-14844 was issued in 1962. The purpose of this paper is to investigate the impact of the revised source terms on the current approach to analyzing control room habitability as required by 10 CFR 50. Sample calculations are presented that identify aspects of the model requiring clarification before the implementation of the revised source terms. 6 refs., 4 tabs

The elephant in the room: The need to re-discover the intersection between poverty, powerlessness and power in ‘Theology and Development’ praxis

Directory of Open Access Journals (Sweden)

Nadine Bowers Du Toit

2016-09-01

Full Text Available South Africa remains a divided community on many levels: socially, racially and socioeconomically. This is no more evident than in the recent protests – most notably waged on university campuses and on the streets in the past year. This, the article argues, is closely related to the need to reclaim the notion of power by those who feel they remain relegated to the social and economic peripheries after over 20 years of democracy. While ‘theology and development’ praxis has been most closely associated in a post-apartheid era with welfare and charity approaches or pragmatic interaction with state and civil society (both of which have been critiqued, what has not been sufficiently addressed is the notion of power which once dominated ecclesiastical discourses. This is the proverbial ‘elephant in the room’, which the article argues must once again be revisited and re-engaged – both within scholarly reflection and within church practice – in order to address these divides.

Revised SWAT. The integrated burnup calculation code system

International Nuclear Information System (INIS)

Suyama, Kenya; Mochizuki, Hiroki; Kiyosumi, Takehide

2000-07-01

SWAT is an integrated burnup code system developed for analysis of post irradiation examination, transmutation of radioactive waste, and burnup credit problem. This report shows an outline and a user's manual of revised SWAT. This revised SWAT includes expansion of functions, increasing supported machines, and correction of several bugs reported from users of previous SWAT. (author)

Revised SWAT. The integrated burnup calculation code system

Energy Technology Data Exchange (ETDEWEB)

Suyama, Kenya; Mochizuki, Hiroki [Department of Fuel Cycle Safety Research, Nuclear Safety Research Center, Tokai Research Establishment, Japan Atomic Energy Research Institute, Tokai, Ibaraki (Japan); Kiyosumi, Takehide [The Japan Research Institute, Ltd., Tokyo (Japan)

2000-07-01

SWAT is an integrated burnup code system developed for analysis of post irradiation examination, transmutation of radioactive waste, and burnup credit problem. This report shows an outline and a user's manual of revised SWAT. This revised SWAT includes expansion of functions, increasing supported machines, and correction of several bugs reported from users of previous SWAT. (author)

Text Revision in Deaf and Hearing Bilingual Students

Science.gov (United States)

Teruggi, Lilia A.; Gutiérrez-Cáceres, Rafaela

2016-01-01

In this study we explored the revision process and strategies implemented by deaf and hearing students who attend the same bilingual school context (LIS and Italian). For that we analysed and compared the types and quality of revisions made by deaf and hearing participants to their first draft of a narrative text ("Frog, Where Are You?")…

Revised Paris and Vienna Nuclear Liability Conventions - Challenges for Nuclear Insurers

International Nuclear Information System (INIS)

Tetley, M.

2006-01-01

The revisions recently implemented to both the Vienna and Paris nuclear liability Conventions are intended to widen significantly the amount and scope of compensation payable in the event of a nuclear accident. Whilst this is a laudable objective, the final extent of the revisions leaves nuclear site operators and their insurers with greater uncertainty as a result of the wider and unquantifiable nature of some aspects of the revised nuclear damage definition, in particular where reference is made to environmental reinstatement and extended prescription periods. Incorporating broader definitions in the Convention revisions will therefore leave gaps in the insurance cover where insurers are unable to insure the new, wider scope of cover. If no insurance is available, then the liability for the revised scope of cover must fall upon either the operator or the national Government. This presentation will give an overview of where and why the major gaps in nuclear liability insurance cover will occur in the revised Conventions; it will also examine the problems in defining the revised scope of cover and will look at where these unquantifiable risks should now reside, to ensure there is equity between the liabilities imposed on the nuclear industry and those imposed on other industrial sectors. (author)

The impact of subsidence on straight and curved modular cementless revision stems in hip revision surgery.

Science.gov (United States)

Fraile Suari, A; Gil González, S; Pérez Prieto, D; León García, A; Mestre Cortadellas, C; Tey Pons, M; Marqués López, F

Subsidence is one of the potential complications in femoral stem revision total hip arthroplasty surgery, and can affect stability and osseointegration. A retrospective study was conducted on the outcomes at one year and 5 years (specifically subsidence and clinical relevance) of 40 consecutive femoral total hip arthroplasty revisions, comparing two modular cementless revision stems, Straight vs. Curved, with 20 patients in each group. No mechanical failure was observed, and there was an improvement in functional outcomes. Mean radiological subsidence was 9.9±4.9mm (straight=10.75mm vs. curved=9.03mm), with no statistically significant difference between groups (p=0,076). Fourteen patients (35%) had ≥10mm of subsidence, up to a maximum of 22mm. The subsidence found in this study is similar to published series, with no short-term clinical manifestations, or an increased number of complications or stem loosening in either the Straight or Curved group. No differences in subsidence were observed at one year and 5 years after surgery between the 2 types of stems. Copyright © 2017 SECOT. Publicado por Elsevier España, S.L.U. All rights reserved.

EPR first responders revision test

International Nuclear Information System (INIS)

2011-01-01

In this revision test evaluates the acquired knowledge in case of radiological emergency confront. Actions to be taken in relation to people, equipment and the environment. Doses, radioactive sources, pollution

Peritoneal Dialysis Access Revision in Children: Causes, Interventions, and Outcomes.

Science.gov (United States)

Borzych-Duzalka, Dagmara; Aki, T Fazil; Azocar, Marta; White, Colin; Harvey, Elizabeth; Mir, Sevgi; Adragna, Marta; Serdaroglu, Erkin; Sinha, Rajiv; Samaille, Charlotte; Vanegas, Juan Jose; Kari, Jameela; Barbosa, Lorena; Bagga, Arvind; Galanti, Monica; Yavascan, Onder; Leozappa, Giovanna; Szczepanska, Maria; Vondrak, Karel; Tse, Kei-Chiu; Schaefer, Franz; Warady, Bradley A

2017-01-06

Little published information is available about access failure in children undergoing chronic peritoneal dialysis. Our objectives were to evaluate frequency, risk factors, interventions, and outcome of peritoneal dialysis access revision. Data were derived from 824 incident and 1629 prevalent patients from 105 pediatric nephrology centers enrolled in the International Pediatric Peritoneal Dialysis Network Registry between 2007 and 2015. In total, 452 access revisions were recorded in 321 (13%) of 2453 patients over 3134 patient-years of follow-up, resulting in an overall access revision rate of 0.14 per treatment year. Among 824 incident patients, 186 (22.6%) underwent 188 access revisions over 1066 patient-years, yielding an access revision rate of 0.17 per treatment year; 83% of access revisions in incident patients were reported within the first year of peritoneal dialysis treatment. Catheter survival rates in incident patients were 84%, 80%, 77%, and 73% at 12, 24, 36, and 48 months, respectively. By multivariate logistic regression analysis, risk of access revision was associated with younger age (odds ratio, 0.93; 95% confidence interval, 0.92 to 0.95; P<0.001), diagnosis of congenital anomalies of the kidney and urinary tract (odds ratio, 1.28; 95% confidence interval, 1.03 to 1.59; P=0.02), coexisting ostomies (odds ratio, 1.42; 95% confidence interval, 1.07 to 1.87; P=0.01), presence of swan neck tunnel with curled intraperitoneal portion (odds ratio, 1.30; 95% confidence interval, 1.04 to 1.63; P=0.02), and high gross national income (odds ratio, 1.10; 95% confidence interval, 1.02 to 1.19; P=0.01). Main reasons for access revisions included mechanical malfunction (60%), peritonitis (16%), exit site infection (12%), and leakage (6%). Need for access revision increased the risk of peritoneal dialysis technique failure or death (hazard ratio, 1.35; 95% confidence interval, 1.10 to 1.65; P=0.003). Access dysfunction due to mechanical causes doubled the risk

Peritoneal Dialysis Access Revision in Children: Causes, Interventions, and Outcomes

Science.gov (United States)

Aki, T. Fazil; Azocar, Marta; White, Colin; Harvey, Elizabeth; Mir, Sevgi; Adragna, Marta; Serdaroglu, Erkin; Sinha, Rajiv; Samaille, Charlotte; Vanegas, Juan Jose; Kari, Jameela; Barbosa, Lorena; Bagga, Arvind; Galanti, Monica; Yavascan, Onder; Leozappa, Giovanna; Szczepanska, Maria; Vondrak, Karel; Tse, Kei-Chiu; Schaefer, Franz; Warady, Bradley A.

2017-01-01

Background and objectives Little published information is available about access failure in children undergoing chronic peritoneal dialysis. Our objectives were to evaluate frequency, risk factors, interventions, and outcome of peritoneal dialysis access revision. Design, setting, participants, & measurements Data were derived from 824 incident and 1629 prevalent patients from 105 pediatric nephrology centers enrolled in the International Pediatric Peritoneal Dialysis Network Registry between 2007 and 2015. Results In total, 452 access revisions were recorded in 321 (13%) of 2453 patients over 3134 patient-years of follow-up, resulting in an overall access revision rate of 0.14 per treatment year. Among 824 incident patients, 186 (22.6%) underwent 188 access revisions over 1066 patient-years, yielding an access revision rate of 0.17 per treatment year; 83% of access revisions in incident patients were reported within the first year of peritoneal dialysis treatment. Catheter survival rates in incident patients were 84%, 80%, 77%, and 73% at 12, 24, 36, and 48 months, respectively. By multivariate logistic regression analysis, risk of access revision was associated with younger age (odds ratio, 0.93; 95% confidence interval, 0.92 to 0.95; P<0.001), diagnosis of congenital anomalies of the kidney and urinary tract (odds ratio, 1.28; 95% confidence interval, 1.03 to 1.59; P=0.02), coexisting ostomies (odds ratio, 1.42; 95% confidence interval, 1.07 to 1.87; P=0.01), presence of swan neck tunnel with curled intraperitoneal portion (odds ratio, 1.30; 95% confidence interval, 1.04 to 1.63; P=0.02), and high gross national income (odds ratio, 1.10; 95% confidence interval, 1.02 to 1.19; P=0.01). Main reasons for access revisions included mechanical malfunction (60%), peritonitis (16%), exit site infection (12%), and leakage (6%). Need for access revision increased the risk of peritoneal dialysis technique failure or death (hazard ratio, 1.35; 95% confidence interval, 1

Pensamentos, sentimentos, vontades e afetos: a fisio-psicologia de Nietzsche a partir do aforismo 19 de Para Além de Bem e Mal

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Bruno Martins Machado

2011-05-01

Full Text Available O presente estudo busca apresentar como a noçáo de fisio-psicologia proposta por Nietzsche se estrutura sobre o corpo e exige uma alteraçáo particular na determinaçáo da noçáo de vontade. Para realizar tal empreendimento, tomamos como parâmetro principalmente o aforismo 19 de Para Além de Bem e Mal. Neste texto, Nietzsche apresenta uma releitura da noçáo de vontade a partir da análise da estrutura dos afetos, dos pensamentos e dos sentimentos. A importância desse empreendimento se justifica por abrir espaço para uma proposta psicológica baseada em um dinamismo que está para além dos processos conscientes.

Resource description and access 2013 revision

CERN Document Server

2013-01-01

This e-book contains the 2013 Revision of RDA: Resource Description and Access, and includes the July 2013 Update. This e-book offers links within the RDA text and the capability of running rudimentary searches of RDA, but please note that this e-book does not have the full range of content or functionality provided by the subscription product RDA Toolkit. Included: A full accumulation of RDA- the revision contains a full set of all current RDA instructions. It replaces the previous version of RDA Print as opposed to being an update packet to that version. RDA has gone through many changes sin

Risk factors for revision of primary total hip arthroplasty: a systematic review

Directory of Open Access Journals (Sweden)

Prokopetz Julian JZ

2012-12-01

Full Text Available Abstract Background Numerous papers have been published examining risk factors for revision of primary total hip arthroplasty (THA, but there have been no comprehensive systematic literature reviews that summarize the most recent findings across a broad range of potential predictors. Methods We performed a PubMed search for papers published between January, 2000 and November, 2010 that provided data on risk factors for revision of primary THA. We collected data on revision for any reason, as well as on revision for aseptic loosening, infection, or dislocation. For each risk factor that was examined in at least three papers, we summarize the number and direction of statistically significant associations reported. Results Eighty-six papers were included in our review. Factors found to be associated with revision included younger age, greater comorbidity, a diagnosis of avascular necrosis (AVN as compared to osteoarthritis (OA, low surgeon volume, and larger femoral head size. Male sex was associated with revision due to aseptic loosening and infection. Longer operating time was associated with revision due to infection. Smaller femoral head size was associated with revision due to dislocation. Conclusions This systematic review of literature published between 2000 and 2010 identified a range of demographic, clinical, surgical, implant, and provider variables associated with the risk of revision following primary THA. These findings can inform discussions between surgeons and patients relating to the risks and benefits of undergoing total hip arthroplasty.

Perioperative transfusion threshold and ambulation after hip revision surgery

DEFF Research Database (Denmark)

Nielsen, Kamilla; Johansson, Pär I; Dahl, Benny

2014-01-01

BACKGROUND: Transfusion with red blood cells (RBC) may be needed during hip revision surgery but the appropriate haemoglobin concentration (Hb) threshold for transfusion has not been well established. We hypothesized that a higher transfusion threshold would improve ambulation after hip revision...... surgery. METHODS: The trial was registered at Clinicaltrials.gov ( NCT00906295). Sixty-six patients aged 18 years or older undergoing hip revision surgery were randomized to receive RBC at a Hb threshold of either 7.3 g/dL (restrictive group) or 8.9 g/dL (liberal group). Postoperative ambulation...... received RBC. CONCLUSIONS: A Hb transfusion threshold of 8.9 g/dL was associated with a statistically significantly faster TUG after hip revision surgery compared to a threshold of 7.3 g/dL but the clinical importance is questionable and the groups did not differ in Hb at the time of testing....

Structured Head and Neck CT Angiography Reporting Reduces Resident Revision Rates.

Science.gov (United States)

Johnson, Tucker F; Brinjikji, Waleed; Doolittle, Derrick A; Nagelschneider, Alex A; Welch, Brian T; Kotsenas, Amy L

2018-04-12

This resident-driven quality improvement project was undertaken to assess the effectiveness of structured reporting to reduce revision rates for afterhours reports dictated by residents. The first part of the study assessed baseline revision rates for head and neck CT angiography (CTA) examinations dictated by residents during afterhours call. A structured report was subsequently created based on templates on the RSNA informatics reporting website and critical findings that should be assessed for on all CTA examinations. The template was made available to residents through the speech recognition software for all head and neck CTA examinations for a duration of 2 months. Report revision rates were then compared with and without use of the structured template. The structured template was found to reduce revision rates by approximately 50% with 10/41 unstructured reports revised and 2/17 structured reports revised. We believe that structured reporting can help reduce reporting errors, particularly in term of typographical errors, train residents to evaluate complex examinations in a systematic fashion, and assist them in recalling critical findings on these examinations. Copyright © 2018 Elsevier Inc. All rights reserved.