Unanswered Questions in the Electroweak Theory

International Nuclear Information System (INIS)

Quigg, Chris

2009-01-01

This article is devoted to the status of the electroweak theory on the eve of experimentation at CERN's Large Hadron Collider. A compact summary of the logic and structure of the electroweak theory precedes an examination of what experimental tests have established so far. The outstanding unconfirmed prediction of the electroweak theory is the existence of the Higgs boson, a weakly interacting spin-zero particle that is the agent of electroweak symmetry breaking, the giver of mass to the weak gauge bosons, the quarks, and the leptons. General arguments imply that the Higgs boson or other new physics is required on the TeV energy scale. Indirect constraints from global analyses of electroweak measurements suggest that the mass of the standard-model Higgs boson is less than 200 GeV. Once its mass is assumed, the properties of the Higgs boson follow from the electroweak theory, and these inform the search for the Higgs boson. Alternative mechanisms for electroweak symmetry breaking are reviewed, and the importance of electroweak symmetry breaking is illuminated by considering a world without a specific mechanism to hide the electroweak symmetry. For all its triumphs, the electroweak theory has many shortcomings.

Pollination ecology in the 21st century: Key Questions for future research

OpenAIRE

STOUT, JANE CATHERINE

2011-01-01

PUBLISHED To inspire new ideas in research on pollination ecology, we list the most important unanswered questions in the field. This list was drawn up by contacting 170 scientists from different areas of pollination ecology and asking them to contribute their opinion on the greatest knowledge gaps that need to be addressed. Almost 40% of them took part in our email poll and we received more than 650 questions and comments, which we classified into different categories repr...

Pollination ecology in the 21st century:key questions for future research

OpenAIRE

Mayer, Caroline; Adler, Lynn; Armbruster, W. Scott; Dafni, Amots; Eardley, Connal; Huang, Shuang-Quan; Kevan, Peter; Ollerton, Jeff; Packer, Laurence; Ssymank, Axel; Stout, Jane C.; Potts, Simon G.

2011-01-01

To inspire new ideas in research on pollination ecology, we list the most important unanswered questions in the field. This list was drawn up by contacting 170 scientists from different areas of pollination ecology and asking them to contribute their opinion on the greatest knowledge gaps that need to be addressed. Almost 40% of them took part in our email poll and we received more than 650 questions and comments, which we classified into different categories representing various aspects of p...

Flower development: open questions and future directions.

Science.gov (United States)

Wellmer, Frank; Bowman, John L; Davies, Brendan; Ferrándiz, Cristina; Fletcher, Jennifer C; Franks, Robert G; Graciet, Emmanuelle; Gregis, Veronica; Ito, Toshiro; Jack, Thomas P; Jiao, Yuling; Kater, Martin M; Ma, Hong; Meyerowitz, Elliot M; Prunet, Nathanaël; Riechmann, José Luis

2014-01-01

Almost three decades of genetic and molecular analyses have resulted in detailed insights into many of the processes that take place during flower development and in the identification of a large number of key regulatory genes that control these processes. Despite this impressive progress, many questions about how flower development is controlled in different angiosperm species remain unanswered. In this chapter, we discuss some of these open questions and the experimental strategies with which they could be addressed. Specifically, we focus on the areas of floral meristem development and patterning, floral organ specification and differentiation, as well as on the molecular mechanisms underlying the evolutionary changes that have led to the astounding variations in flower size and architecture among extant and extinct angiosperms.

Pollination ecology in the 21st Century: key questions for future research\\ud

OpenAIRE

Mayer, Carolin; Adler, Lynn; Armbruster, W Scott; Dafni, Amots; Eardley, Connal; Huang, Shuang-Quan; Kevan, Peter G; Ollerton, Jeff; Packer, Laurence; Ssymank, Axel; Stout, Jane C; Potts, Simon G

2011-01-01

To inspire new ideas in research on pollination ecology, we list the most important unanswered questions in the field. This list was drawn up by contacting 170 scientists from different areas of pollination ecology and asking them to contribute their opinion on the greatest knowledge gaps that need to be addressed. Almost 40% of them took part in our email poll and we received more than 650 questions and comments, which we classified into different categories representing various aspects of p...

Guarino Guarini open questions, possible solutions

CERN Document Server

2009-01-01

Baroque architect and mathematician Guarino Guarini is the subject of this issue of the Nexus Network Journal. A group of international scholars were invited to contribute papers that shed light on the unanswered questions in several areas: Baroque architecture in general and Guarini’s architecture in particular; philosophy; history of structural mechanics; mathematics and history of mathematics, cosmology. As always, the NNJ takes an interdisciplinary approach to the broad range of subjects that Guarini concerned himself with, thus the final results will add significantly to our understanding of how Guarini’s actual practical and technical processes were informed by knowledge of his multifaceted scientific and philosophical interests.

Disability Discrimination and Obesity: The Big Questions?

Science.gov (United States)

Flint, Stuart W; Snook, Jeremé

2015-12-01

Obesity discrimination in employment and recruitment has become a topic of focus for research examination with increasing reports of discrimination by colleagues and managers. Whilst a limited number of legal cases have emerged, disability law is consulted in line with the expectation of anti-discriminatory practices at work. In line with disability law, whether obesity is defined as a disability or not has an impact on the outcome of a court ruling. Ambiguity when defining obesity through either the medical or social model means there are many questions that remain unanswered which might lead to inconsistency in court rulings.

The cyclopurine deoxynucleosides: DNA repair, biological effects, mechanistic insights, and unanswered questions.

Science.gov (United States)

Brooks, Philip J

2017-06-01

Patients with the genetic disease xeroderma pigmentosum (XP) who lack the capacity to carry out nucleotides excision repair (NER) have a dramatically elevated risk of skin cancer on sun exposed areas of the body. NER is the DNA repair mechanism responsible for the removal of DNA lesions resulting from ultraviolet light. In addition, a subset of XP patients develop a progressive neurodegenerative disease, referred to as XP neurologic disease, which is thought to be the result of accumulation of endogenous DNA lesions that are repaired by NER but not other repair pathways. The 8,5-cyclopurine deoxynucleotides (cyPu) have emerged as leading candidates for such lesions, in that they result from the reaction of the hydroxyl radical with DNA, are strong blocks to transcription in human cells, and are repaired by NER but not base excision repair. Here I present a focused perspective on progress into understating the repair and biological effects of these lesions. In doing so, I emphasize the role of Tomas Lindahl and his laboratory in stimulating cyPu research. I also include a critical evaluation of the evidence supporting a role for cyPu lesions in XP neurologic disease, with a focus on outstanding questions, and conceptual and technologic challenges. Copyright © 2017. Published by Elsevier Inc.

To autoregulate or not to autoregulate--that is no longer the question

DEFF Research Database (Denmark)

Greisen, Gorm

2009-01-01

In the late 1970s, high cerebral blood flow was perceived as a cause of intracranial hemorrhage in the preterm infant. Intracranial hemorrhage was diagnosed by computed tomography and ultrasound found to be frequent not only in babies who died. Hemorrhage was soon linked to cerebral palsy...... involved in cerebral blood flow and oxygenation. Meanwhile, some basic questions regarding autoregulation remain unanswered, and some concepts from the 1970s still direct clinical practice....

Serum levels of brain-derived neurotrophic factor in major depressive disorder: state-trait issues, clinical features and pharmacological treatment

NARCIS (Netherlands)

Molendijk, M.L.; Bus, B.A.A.; Spinhoven, P.; Penninx, B.W.J.H.; Kenis, G.; Prickaerts, J.; Voshaar, R.C.O.; Elzinga, B.M.

2011-01-01

Recent evidence supports 'the neurotrophin hypothesis of depression' in its prediction that brain-derived neurotrophic factor (BDNF) is involved in depression. However, some key questions remain unanswered, including whether abnormalities in BDNF persist beyond the clinical state of depression,

IIIB or not IIIB: a previously unanswered question.

Science.gov (United States)

Thibodeau, Jennifer T; Mishkin, Joseph D; Patel, Parag C; Mammen, Pradeep P A; Markham, David W; Drazner, Mark H

2012-05-01

The term New York Heart Association (NYHA) class IIIB has been used increasingly in clinical medicine, including as an inclusion criteria for many clinical trials assessing left ventricular assist devices (LVADs). Indeed, NYHA class IIIB is incorporated in the Food and Drug Administration's approved indication for the Heartmate II. However, on review of the medical literature, we found that there is no consensus definition of NYHA class IIIB. Until the ambiguity is resolved, we suggest that this designation not be used in clinical practice or by investigators leading clinical trials assessing therapies which convey substantial risk to patients and therefore require clarity in describing the enrolled patient population. With ongoing improvements in LVADs, this therapy will increasingly be considered in patients less sick than those who require inotropic support, providing urgency to establish a consensus system of classifying such patients who nevertheless fall within the spectrum of advanced heart failure. Herein we propose a modification of the standard NYHA classification system which can be used to fill this void. Copyright © 2012 Elsevier Inc. All rights reserved.

Dynamical scaling laws – A few unanswered questions

Indian Academy of Sciences (India)

a highly nonlinear process far from equilibrium. The second phase grows with ... The scaling hypothesis assumes the existence of a single characteristic length scale L(t) such that the domain sizes and ... the mean density of the medium varies as a function of distance from a given point, should exhibit the scaling form with ...

In the Gray Zone in the Fragile X Gene: What are the Key Unanswered Clinical and Biological Questions?

Directory of Open Access Journals (Sweden)

Deborah A. Hall

2014-06-01

Full Text Available Smaller expansions (41–54 CGG repeats in the fragile X mental retardation 1 (FMR1 gene are termed "gray zone" alleles. Only recently has interest in these expansions increased due to reporting of phenotypes unique to gray zone carriers or similar to those seen in individuals with larger expansions. As minimal research has focused on gray zone expansions, this paper asks several questions related to this topic. These include the following: What is the definition of the gray zone? Is there a risk of developing neurological signs in these carriers? Are there secondary gene effects that impact gray zone alleles or a biologic advantage to carrying these repeats? How do we counsel patients with gray zone expansions? The answers to these questions will help to determine the significance of these expansions and provide needed information to the research community and clinicians.

Rapid Response Teams: Is it Time to Reframe the Questions of Rapid Response Team Measurement?

Science.gov (United States)

Salvatierra, Gail G; Bindler, Ruth C; Daratha, Kenn B

2016-11-01

The purpose of this article is to present an overview of rapid response team (RRT) history in the United States, provide a review of prior RRT effectiveness research, and propose the reframing of four new questions of RRT measurement that are designed to better understand RRTs in the context of contemporary nursing practice as well as patient outcomes. RRTs were adopted in the United States because of their intuitive appeal, and despite a lack of evidence for their effectiveness. Subsequent studies used mortality and cardiac arrest rates to measure whether or not RRTs "work." Few studies have thoroughly examined the effect of RRTs on nurses and on nursing practice. An extensive literature review provided the background. Suppositions and four critical, unanswered questions arising from the literature are suggested. The results of RRT effectiveness, which have focused on patient-oriented outcomes, have been ambiguous, contradictory, and difficult to interpret. Additionally, they have not taken into account the multiple ways in which these teams have impacted nurses and nursing practice as well as patient outcomes. What happens in terms of RRT process and utilization is likely to have a major impact on nurses and nursing care on general medical and surgical wards. What that impact will be depends on what we can learn from measuring with an expanded yardstick, in order to answer the question, "Do RRTs work?" Evidence for the benefits of RRTs depends on proper framing of questions relating to their effectiveness, including the multiple ways RRTs contribute to nursing efficacy. © 2016 Sigma Theta Tau International.

Health-Related Quality of Life (HRQOL Measures: There are Still Many Unanswered Questions about Human Life

Directory of Open Access Journals (Sweden)

Mayowa Ojo Owolabi

2008-01-01

Full Text Available Health-related quality of life (HRQOL measures are used to assess the multifaceted impact of disease, and determine the utility and associated disability. In addition, the impact of medical interventions must be assessed by psychometrically robust HRQOL measures based on a comprehensive and dynamic model. To develop such a model, the concepts of life, its quality, domains, essence, and purpose must be properly and clearly understood. The correct understanding of these entities is specifically important for patient-centered medicine and has universal implications for all fields of human endeavor. Therefore, in order to explore questions about life and quality of life adequately, every necessary field of knowledge should be employed. A multilinguistic and etymological appraisal reveals that life is related to medicine, freedom, being, soul, and spirit, all of which must therefore be considered in its conceptualization.

Provider Initiated Testing and Counseling (PITC for HIV in resource-limited clinical settings: important questions unanswered

Directory of Open Access Journals (Sweden)

Peter Twyman

2009-09-01

Full Text Available Testing is the gateway to HIV care and support services, and efforts to broaden treatment must include a proactive and inclusive approach to testing. Provider Initiated Testing and Counseling (PITC for HIV utilizes the opportunity afforded by the clinical encounter for the care provider to make a clinical recommendation that the patient have a voluntary HIV test. It is hoped that by broadening testing by such strategies as PITC more patients may be identified and linked to treatment and support. However, there exist multiple challenges and questions regarding the provision of routine HIV testing and counseling in clinical facilities. In order to support further PITC efforts and scale up of current testing programs, a research agenda that addresses the ethical, social and operational components of PITC programming in health facilities, is critically needed to further guide its expansion.

Frequency and change mechanisms of psychotherapy among depressed patients: study protocol for a multicenter randomized trial comparing twice-weekly versus once-weekly sessions of CBT and IPT

NARCIS (Netherlands)

Bruijniks, S.J.; Bosmans, J.; Peeters, F.P.M.L.; Hollon, S.D.; van Oppen, P.; van den Boogaard, M.; Dingemanse, P.; Cuijpers, P.; Arntz, A.; Franx, G.; Huibers, M.J.H.

2015-01-01

Background: Cognitive behavioral therapy (CBT) and interpersonal therapy (IPT) are among the most well established therapies for the treatment of depression. However, some major questions remain unanswered. First, it is unknown what session frequency results in the most optimal (cost) effectiveness

Pollination ecology in the 21st Century: Key questions for future research

Directory of Open Access Journals (Sweden)

Jane C. Stout

2011-03-01

Full Text Available To inspire new ideas in research on pollination ecology, we list the most important unanswered questions in the field. This list was drawn up by contacting 170 scientists from different areas of pollination ecology and asking them to contribute their opinion on the greatest knowledge gaps that need to be addressed. Almost 40% of them took part in our email poll and we received more than 650 questions and comments, which we classified into different categories representing various aspects of pollination research. The original questions were merged and synthesised, and a final vote and ranking led to the resultant list. The categories cover plant sexual reproduction, pollen and stigma biology, abiotic pollination, evolution of animal-mediated pollination, interactions of pollinators and floral antagonists, pollinator behaviour, taxonomy, plant-pollinator assemblages, geographical trends in diversity, drivers of pollinator loss, ecosystem services, management of pollination, and conservation issues such as the implementation of pollinator conservation. We focused on questions that were of a broad scope rather than case-specific; thus, addressing some questions may not be feasible within single research projects but constitute a general guide for future directions. With this compilation we hope to raise awareness of pollination-related topics not only among researchers but also among non-specialists including policy makers, funding agencies and the public at large.

The Unanswered Question of Musical Meaning. : A Cross-Domain Approach

NARCIS (Netherlands)

Tom Langhorst

2014-01-01

Designing meaningful audio for interactive applications such as video games or sonic user interfaces, presents designers with several challenges. One challenge is the fact that the perception of musical meaning involves cultural or learned aspects when it comes to tonality (Huron, 2006; Patel,

Telomere Shortening in Neurological Disorders: An Abundance of Unanswered Questions

OpenAIRE

Eitan, Erez; Hutchison, Emmette R.; Mattson, Mark P.

2014-01-01

Telomeres, ribonucleoprotein complexes that cap eukaryotic chromosomes, typically shorten in leukocytes with aging. Aging is a primary risk factor for neurodegenerative disease (ND), and a common assumption has arisen that leukocyte telomere length (LTL) can serve as a predictor of neurological disease. However, the evidence for shorter LTL in Alzheimer’s and Parkinson’s patients is inconsistent. The diverse causes of telomere shortening may explain variability in LTL between studies and indi...

Aging issues: unanswered questions in marital and family therapy literature.

Science.gov (United States)

Lambert-Shute, Jennifer; Fruhauf, Christine A

2011-01-01

Researchers have reviewed couple and family therapy journals to determine the extent to which issues concerning older populations are addressed. In an effort to extend previous work, we conducted content analyses of 957 articles published in three of the leading marital and family therapy journals between 1997 and 2006. From the articles, 27 (2.8%) mentioned aging or included older adults in their sample. Results indicate that the number of articles emphasizing older adults has not substantially increased. While this result has been substantiated by other researchers in previous years, a new finding in this study concerns the quality of articles on aging issues. The articles reviewed in this study indicated a greater focus on aging issues and addressing issues during this life cycle stage. © 2011 American Association for Marriage and Family Therapy.

Medical Rights of Minors: Some Answered and Unanswered Legal Questions.

Science.gov (United States)

Talbutt, Lou

1980-01-01

Because school counselors work with minors they must keep up with current laws, as well as state and local school policies. Special caution is needed concerning medical rights of minors and parental consent in dealing with student pregnancy, abortion, drug abuse, and child abuse. (JAC)

Emotion theory and research: highlights, unanswered questions, and emerging issues.

Science.gov (United States)

Izard, Carroll E

2009-01-01

Emotion feeling is a phase of neurobiological activity, the key component of emotions and emotion-cognition interactions. Emotion schemas, the most frequently occurring emotion experiences, are dynamic emotion-cognition interactions that may consist of momentary/situational responding or enduring traits of personality that emerge over developmental time. Emotions play a critical role in the evolution of consciousness and the operations of all mental processes. Types of emotion relate differentially to types or levels of consciousness. Unbridled imagination and the ability for sympathetic regulation of empathy may represent both potential gains and losses from the evolution and ontogeny of emotion processes and consciousness. Unresolved issues include psychology's neglect of levels of consciousness that are distinct from access or reflective consciousness and use of the term "unconscious mind" as a dumpster for all mental processes that are considered unreportable. The relation of memes and the mirror neuron system to empathy, sympathy, and cultural influences on the development of socioemotional skills are unresolved issues destined to attract future research.

Answers to Health Questions: Internet Search Results Versus Online Health Community Responses.

Science.gov (United States)

Kanthawala, Shaheen; Vermeesch, Amber; Given, Barbara; Huh, Jina

2016-04-28

About 6 million people search for health information on the Internet each day in the United States. Both patients and caregivers search for information about prescribed courses of treatments, unanswered questions after a visit to their providers, or diet and exercise regimens. Past literature has indicated potential challenges around quality in health information available on the Internet. However, diverse information exists on the Internet-ranging from government-initiated webpages to personal blog pages. Yet we do not fully understand the strengths and weaknesses of different types of information available on the Internet. The objective of this research was to investigate the strengths and challenges of various types of health information available online and to suggest what information sources best fit various question types. We collected questions posted to and the responses they received from an online diabetes community and classified them according to Rothwell's classification of question types (fact, policy, or value questions). We selected 60 questions (20 each of fact, policy, and value) and the replies the questions received from the community. We then searched for responses to the same questions using a search engine and recorded the Community responses answered more questions than did search results overall. Search results were most effective in answering value questions and least effective in answering policy questions. Community responses answered questions across question types at an equivalent rate, but most answered policy questions and the least answered fact questions. Value questions were most answered by community responses, but some of these answers provided by the community were incorrect. Fact question search results were the most clinically valid. The Internet is a prevalent source of health information for people. The information quality people encounter online can have a large impact on them. We present what kinds of questions people ask

Form and function: Perspectives on structural biology and resources for the future

International Nuclear Information System (INIS)

Vaughan, D.

1990-12-01

The purpose of this study is largely to explore and expand on the thesis that biological structures and their functions are suited to. Form indeed follows function and if we are to understand the workings of a living system, with all that such an understanding promises, we must first seek to describe the structure of its parts. Descriptions of a few achievements of structural biology lay the groundwork, but the substance of this booklet is a discussion of important questions yet unanswered and opportunities just beyond our grasp. The concluding pages then outline a course of action in which the Department of Energy would exercise its responsibility to develop the major resources needed to extend our reach and to answer some of those unanswered questions. 22 figs

Form and function: Perspectives on structural biology and resources for the future

Energy Technology Data Exchange (ETDEWEB)

Vaughan, D. (ed.)

1990-12-01

The purpose of this study is largely to explore and expand on the thesis that biological structures and their functions are suited to. Form indeed follows function and if we are to understand the workings of a living system, with all that such an understanding promises, we must first seek to describe the structure of its parts. Descriptions of a few achievements of structural biology lay the groundwork, but the substance of this booklet is a discussion of important questions yet unanswered and opportunities just beyond our grasp. The concluding pages then outline a course of action in which the Department of Energy would exercise its responsibility to develop the major resources needed to extend our reach and to answer some of those unanswered questions. 22 figs.

Titan's cold case files - Outstanding questions after Cassini-Huygens

Science.gov (United States)

Nixon, C. A.; Lorenz, R. D.; Achterberg, R. K.; Buch, A.; Coll, P.; Clark, R. N.; Courtin, R.; Hayes, A.; Iess, L.; Johnson, R. E.; Lopes, R. M. C.; Mastrogiuseppe, M.; Mandt, K.; Mitchell, D. G.; Raulin, F.; Rymer, A. M.; Todd Smith, H.; Solomonidou, A.; Sotin, C.; Strobel, D.; Turtle, E. P.; Vuitton, V.; West, R. A.; Yelle, R. V.

2018-06-01

The entry of the Cassini-Huygens spacecraft into orbit around Saturn in July 2004 marked the start of a golden era in the exploration of Titan, Saturn's giant moon. During the Prime Mission (2004-2008), ground-breaking discoveries were made by the Cassini orbiter including the equatorial dune fields (flyby T3, 2005), northern lakes and seas (T16, 2006), and the large positive and negative ions (T16 & T18, 2006), to name a few. In 2005 the Huygens probe descended through Titan's atmosphere, taking the first close-up pictures of the surface, including large networks of dendritic channels leading to a dried-up seabed, and also obtaining detailed profiles of temperature and gas composition during the atmospheric descent. The discoveries continued through the Equinox Mission (2008-2010) and Solstice Mission (2010-2017) totaling 127 targeted flybys of Titan in all. Now at the end of the mission, we are able to look back on the high-level scientific questions from the start of the mission, and assess the progress that has been made towards answering these. At the same time, new scientific questions regarding Titan have emerged from the discoveries that have been made. In this paper we review a cross-section of important scientific questions that remain partially or completely unanswered, ranging from Titan's deep interior to the exosphere. Our intention is to help formulate the science goals for the next generation of planetary missions to Titan, and to stimulate new experimental, observational and theoretical investigations in the interim.

Artificial Intelligence in Medical Practice: The Question to the Answer?

Science.gov (United States)

Miller, D Douglas; Brown, Eric W

2018-02-01

Computer science advances and ultra-fast computing speeds find artificial intelligence (AI) broadly benefitting modern society-forecasting weather, recognizing faces, detecting fraud, and deciphering genomics. AI's future role in medical practice remains an unanswered question. Machines (computers) learn to detect patterns not decipherable using biostatistics by processing massive datasets (big data) through layered mathematical models (algorithms). Correcting algorithm mistakes (training) adds to AI predictive model confidence. AI is being successfully applied for image analysis in radiology, pathology, and dermatology, with diagnostic speed exceeding, and accuracy paralleling, medical experts. While diagnostic confidence never reaches 100%, combining machines plus physicians reliably enhances system performance. Cognitive programs are impacting medical practice by applying natural language processing to read the rapidly expanding scientific literature and collate years of diverse electronic medical records. In this and other ways, AI may optimize the care trajectory of chronic disease patients, suggest precision therapies for complex illnesses, reduce medical errors, and improve subject enrollment into clinical trials. Copyright © 2018 Elsevier Inc. All rights reserved.

The relationship between facilitators' questions and the level of reflection in postsimulation debriefing.

Science.gov (United States)

Husebø, Sissel Eikeland; Dieckmann, Peter; Rystedt, Hans; Søreide, Eldar; Friberg, Febe

2013-06-01

Simulation-based education is a learner-active method that may enhance teamwork skills such as leadership and communication. The importance of postsimulation debriefing to promote reflection is well accepted, but many questions concerning whether and how faculty promote reflection remain largely unanswered in the research literature. The aim of this study was therefore to explore the depth of reflection expressed in questions by facilitators and responses from nursing students during postsimulation debriefings. Eighty-one nursing students and 4 facilitators participated. The data were collected in February and March 2008, the analysis being conducted on 24 video-recorded debriefings from simulated resuscitation teamwork involving nursing students only. Using Gibbs' reflective cycle, we graded the facilitators' questions and nursing students' responses into stages of reflection and then correlated these. Facilitators asked most evaluative and fewest emotional questions, whereas nursing students answered most evaluative and analytic responses and fewest emotional responses. The greatest difference between facilitators and nursing students was in the analytic stage. Only 23 (20%) of 117 questions asked by the facilitators were analytic, whereas 45 (35%) of 130 students' responses were rated as analytic. Nevertheless, the facilitators' descriptive questions also elicited student responses in other stages such as evaluative and analytic responses. We found that postsimulation debriefings provide students with the opportunity to reflect on their simulation experience. Still, if the debriefing is going to pave the way for student reflection, it is necessary to work further on structuring the debriefing to facilitate deeper reflection. Furthermore, it is important that facilitators consider what kind of questions they ask to promote reflection. We think future research on debriefing should focus on developing an analytical framework for grading reflective questions. Such

Tenofovir alafenamide (TAF) treatment of HBV, what are the unanswered questions?

Science.gov (United States)

Viganò, Mauro; Loglio, Alessandro; Grossi, Glenda; Lampertico, Pietro

2018-02-01

Tenofovir disoproxil fumarate (TDF), an ester prodrug of tenofovir (TFV), is one of the recommended drugs for chronic hepatitis B (CHB) patients. However, reduced kidney function and loss of bone mineral density have been reported in some CHB patients treated with TDF. Consequent to these safety issues, tenofovir alafenamide (TAF) [Vemlidy®], a phosphonate prodrug of TFV, was developed for the treatment of CHB patients. Areas covered: The favourable pharmacological profile of TAF allows a marked reduction in dosage (25 mg/day) thus reducing systemic exposure to tenofovir and improving the bone and renal safety, keeping however the same virological efficacy, compared to TDF 300 mg/day. In two ongoing 96-week phase III trials in mainly treatment-naive HBeAg-positive or -negative patients, TAF showed similar viral suppression but was associated with significantly higher alanine aminotransferase normalization rates and more favourable renal and bone safety compared to TDF. In a 48-week TAF switch study enrolling patients treated with TDF for 96 weeks, glomerular, tubular and bone safety parameters rapidly improved while virological suppression was maintained. Expert commentary: Waiting long-term large scale clinical practice studies aimed to confirm these advantages, TAF represents an helpful treatment option for both naïve and TDF-exposed CHB patients.

Drug-Resistant Tuberculosis-Current Dilemmas, Unanswered Questions, Challenges, and Priority Needs

NARCIS (Netherlands)

Zumla, Alimuddin; Abubakar, Ibrahim; Raviglione, Mario; Hoelscher, Michael; Ditiu, Lucica; McHugh, Timothy D.; Squire, S. Bertel; Cox, Helen; Ford, Nathan; McNerney, Ruth; Marais, Ben; Grobusch, Martin; Lawn, Stephen D.; Migliori, Giovanni-Battista; Mwaba, Peter; O'Grady, Justin; Pletschette, Michel; Ramsay, Andrew; Chakaya, Jeremiah; Schito, Marco; Swaminathan, Soumya; Memish, Ziad; Maeurer, Markus; Atun, Rifat

2012-01-01

Tuberculosis was declared a global emergency by the World Health Organization (WHO) in 1993. Following the declaration and the promotion in 1995 of directly observed treatment short course (DOTS), a cost-effective strategy to contain the tuberculosis epidemic, nearly 7 million lives have been saved

Major questions about derivation of variance-covariance information for nuclear data evaluations

International Nuclear Information System (INIS)

Peelle, R.W.

1982-01-01

The uncertainties in and correlations among some evaluated nuclear data are now evaluated to permit estimation of data-related uncertainties in the outputs of neutronic calculations and to focus data improvement efforts. Questions are discussed that arise in trying to obtain adequate numerical files of variance-covariance uncertainty information. These involve (1) discrepant data, (2) experimental data with incompletely reported uncertainties, (3) uncertainties in nuclear model results, (4) uncertainty data for the resonance regions and for angle and energy distributions, and (5) the role of integral data in nuclear data evaluation. The question also arises whether files of uncertainty data designed for technological applications can suffice to represent past knowledge in an evaluation that includes new data. Directions are indicated toward resolving these questions

Children's Media Use and Sleep Problems: Issues and Unanswered Questions. Research Brief

Science.gov (United States)

Zimmerman, Frederick J.

2008-01-01

Research shows that most children and adolescents do not get enough high-quality sleep, and that their sleep times appear to have declined over the last two decades. Coinciding with this trend has been the rise in popularity of new media forms including the Internet, video games, cell phones and DVDs. Because of the immediacy and interactivity of…

Regulatory T-cells in autoimmune diseases: challenges, controversies and--yet--unanswered questions.

Science.gov (United States)

Grant, Charlotte R; Liberal, Rodrigo; Mieli-Vergani, Giorgina; Vergani, Diego; Longhi, Maria Serena

2015-02-01

Regulatory T cells (Tregs) are central to the maintenance of self-tolerance and tissue homeostasis. Markers commonly used to define human Tregs in the research setting include high expression of CD25, FOXP3 positivity and low expression/negativity for CD127. Many other markers have been proposed, but none unequivocally identifies bona fide Tregs. Tregs are equipped with an array of mechanisms of suppression, including the modulation of antigen presenting cell maturation and function, the killing of target cells, the disruption of metabolic pathways and the production of anti-inflammatory cytokines. Treg impairment has been reported in a number of human autoimmune conditions and includes Treg numerical and functional defects and conversion into effector cells in response to inflammation. In addition to intrinsic Treg impairment, resistance of effector T cells to Treg control has been described. Discrepancies in the literature are common, reflecting differences in the choice of study participants and the technical challenges associated with investigating this cell population. Studies differ in terms of the methodology used to define and isolate putative regulatory cells and to assess their suppressive function. In this review we outline studies describing Treg frequency and suppressive function in systemic and organ specific autoimmune diseases, with a specific focus on the challenges faced when investigating Tregs in these conditions. Copyright © 2014 Elsevier B.V. All rights reserved.

Talent identification and specialization in sport: an overview of some unanswered questions.

Science.gov (United States)

Gonçalves C, E B; Rama L, M L; Figueiredo, António B

2012-12-01

The theory of deliberate practice postulates that experts are always made, not born. This theory translated to the youth-sport domain means that if athletes want to be high-level performers, they need to deliberately engage in practice during the specialization years, spending time wisely and always focusing on tasks that challenge current performance. Sport organizations in several countries around the world created specialized training centers where selected young talents practice under the supervision of experienced coaches in order to become professional athletes and integrate onto youth national teams. Early specialization and accurate observation by expert coaches or scouts remain the only tools to find a potential excellent athlete among a great number of participants. In the current study, the authors present 2 of the problems raised by talent search and the risks of such a search. Growth and maturation are important concepts to better understand the identification, selection, and development processes of young athletes. However, the literature suggests that sport-promoting strategies are being maintained despite the increased demands in the anthropometric characteristics of professional players and demands of actual professional soccer competitions. On the other hand, identifying biological variables that can predict performance is almost impossible.

Timing of return from altitude training for optimal sea level performance.

Science.gov (United States)

Chapman, Robert F; Laymon Stickford, Abigail S; Lundby, Carsten; Levine, Benjamin D

2014-04-01

While a number of published studies exist to guide endurance athletes with the best practices regarding implementation of altitude training, a key unanswered question concerns the proper timing of return to sea level prior to major competitions. Evidence reviewed here suggests that, altogether, the deacclimatization responses of hematological, ventilatory, and biomechanical factors with return to sea level likely interact to determine the best timing for competitive performance.

Fuel conservation integrated into airline economics

Energy Technology Data Exchange (ETDEWEB)

Ferguson, D.R.

1981-01-01

Fuel conservation efforts at most major airlines involve close scrutiny and intensive analysis in all areas - flight, maintenance and ground handling. Yet, despite the concern and attention devoted, the fundamental question of fuel saving versus time trade-offs remains unanswered. This paper introduces and defines the concept ''The value of an airplane to an airline is that airplane's earning power.

Repetitive Questioning II

Directory of Open Access Journals (Sweden)

R. C. Hamdy MD

2018-02-01

Full Text Available Repetitive questioning is a major problem for caregivers, particularly taxing if they are unable to recognize and understand the reasons why their loved one keeps asking the same question over and over again. Caregivers may be tempted to believe that the patient does not even try to remember the answer given or is just getting obnoxious. This is incorrect. Repetitive questioning is due to the underlying disease: The patient’s short term memory is impaired and he is unable to register, encode, retain and retrieve the answer. If he is concerned about a particular topic, he will keep asking the same question over and over again. To the patient each time she asks the question, it is as if she asked it for the first time. Just answering repetitive questioning by providing repeatedly the same answer is not sufficient. Caregivers should try to identify the underlying cause for this repetitive questioning. In an earlier case study, the patient was concerned about her and her family’s safety and kept asking whether the doors are locked. In this present case study, the patient does not know how to handle the awkward situation he finds himself in. He just does not know what to do. He is not able to adjust to the new unexpected situation. So he repeatedly wants to reassure himself that he is not intruding by asking the same question over and over again. We discuss how the patient’s son-in-law could have avoided this situation and averted the catastrophic ending.

The origin of the future ten questions for the next ten years

CERN Document Server

Gribbin, John

2006-01-01

How did the universe begin? Where do galaxies come from? How do stars and planets form? Where do the material particles we are made of come from? How did life begin? Today we have only provisional answers to such questions. But scientific progress will improve these answers dramatically over the next ten years, predicts John Gribbin in this riveting book. He focuses on what we know—or think we know—about ten controversial, unanswered issues in the physical sciences and explains how current cutting-edge research may yield solutions in the very near future. With his trademark facility for engaging readers with or without a scientific background, the author explores ideas concerning the creation of the universe, the possibility of other forms of life, and the fate of the expanding cosmos. He examines “theories of everything,” including grand unified theories and string theory, and he discusses the Big Bang theory, the origin of structure and patterns of matter in the galaxies, and dark mass and dark ene...

CURBSIDE CONSULTATION IN KNEE ARTHROPLASTY: 49 CLINICAL QUESTIONS

Directory of Open Access Journals (Sweden)

Craig J. Della Vale

2008-12-01

Full Text Available A user- friendly reference for decision making in complicated cases of knee arthroplasty desingned in a question and answers format composed of articles containing current concepts and preferences of experts in total knee replacement surgery, enhanced by several images, diagrams and references and written in the form of a casual advice by Craig J. Della Vale, MD. and his collaborators. PURPOSE By this practical reference of knee arthroplasty, the editor and the contributors have aimed providing straightforward and brief answers, evidence-based advices, their preference and opinions containing current concepts for unanswered questions about complicated cases in total knee replacement surgery which are often controversial and not addressed clearly in traditional knee arthroplasty references. FEATURES There are 49 subjects each written by a different expert designed in 4 sections in a question and answers format including several images and diagrams and also essential references at the end of each article. In the first section preoperative questions is subjected including indications, unicompartmental osteoarthritis of the knee, patient with vascular problems, donating blood, bilateral arthroplasty, patellar resurfacing, range of motion, bearing surface, contraindications, teaching class for patients prior surgery. The second section is about intraoperative questions including skin incision, patella femoral maltracking, femoral component rotation, tibial component rotation, lateral release, femoral component sizing, flexion instability, varus deformity, and valgus deformity, tightness in extension, iatrogenic MCL injury, antibiotic-loaded cement, and perioperative pain. The third section subjects postoperative questions including wound drainage, preventing tromboembolic events, vascular complications, foot drop, manipulation under anesthesia, patella fractures, supracondylar femur fractures, acute extensor mechanism disruptions. In the fourth

A Decision Tree for Psychology Majors: Supplying Questions as Well as Answers.

Science.gov (United States)

Poe, Retta E.

1988-01-01

Outlines the development of a psychology careers decision tree to help faculty advise students plan their program. States that students using the decision tree may benefit by learning more about their career options and by acquiring better question-asking skills. (GEA)

The ecological crisis: a question of justice

International Nuclear Information System (INIS)

Kempf, H.

2010-01-01

The question of ecology has become a major issue for international relations in the next half-century. But it poses new problems of worldwide justice more than questions of power politics, and its solution will always be a reflection of internal social issues in the countries concerned. (author)

Questioning the Questions

Science.gov (United States)

Tienken, Christopher H.; Goldberg, Stephanie; DiRocco, Dominic

2010-01-01

Historical accounts of questioning used in the education process trace back to Socrates. One of the best examples of his use of questioning is found in Plato's "The Republic." Socrates used a series of strategic questions to help his student Glaucon come to understand the concept of justice. Socrates purposefully posed a series of…

Commentary: Recommendations and remaining questions for health care leadership training programs.

Science.gov (United States)

Stoller, James K

2013-01-01

Effective leadership is critical for optimizing cost, access, and quality in health care. Creating a pipeline of effective health care leaders requires developing leadership competencies that differ from the usual criteria of clinical and scientific excellence by which physicians have traditionally been promoted to leadership positions. Specific competencies that differentiate effective leaders from average leaders, especially emotional intelligence and its component abilities, are essential for effective leadership.Adopting a long-standing practice from successful corporations, some health care institutions, medical societies, and business schools now offer leadership programs that address these differentiating leadership competencies. The author draws on experience with such programs through the Cleveland Clinic Academy to provide recommendations for health care leadership training and to identify unanswered questions about such programs.The author recommends that such training should be broadly available to all health care leadership communities (i.e., nurses, administrators, and physicians). A progressive curriculum, starting with foundational concepts and extending to coaching and feedback opportunities through experiential learning, recognizes the challenge of becoming an effective leader and the long time line needed to do so. Linking leadership courses to continuing medical education and to graduate credit opportunities is appealing to participants. Other recommendations focus on the importance of current leaders' involvement in nominating emerging leaders for participation, embedding leadership development discussions in faculty's professional reviews, and blending discussion of frameworks and theory with practical, experiential lessons. The author identifies questions about the benefits of formal health care leadership training that remain to be answered.

[Current recommendations for basic/advanced life support : Addressing unanswered questions and future prospects].

Science.gov (United States)

Fink, K; Schmid, B; Busch, H-J

2016-11-01

The revised guidelines for cardiopulmonary resuscitation were implemented by the European Resuscitation Council (ERC) in October 2015. There were few changes concerning basic and advanced life support; however, some issues were clarified compared to the ERC recommendations from 2010. The present paper summarizes the procedures of basic and advanced life support according to the current guidelines and highlights the updates of 2015. Furthermore, the article depicts future prospects of cardiopulmonary resuscitation that may improve outcome of patients after cardiac arrest in the future.

CURBSIDE CONSULTATION OF THE ACL: 49 CLINICAL QUESTIONS

Directory of Open Access Journals (Sweden)

Bernard R. Bach

2008-09-01

, pain and instability, one stage ACL reconstruction and HTO, patellar fracture in patients with patellar tendon graft, tunnel position in revision setting. The fifth section is about pediatric/adolescent patients including, ACL injury in adolescent with open growth plates, surgical options in adolescents, the risk for adoles-cent females, the risk for opposite side, prevention pro-gram. The last chapter is about miscellaneous questions including non-operative treatment protocol, long-term implications of recurrent instability, and implications of ACL reconstruction on future development of degenera-tive arthritis. AUDIENCE Medical students, orthopedic residents, fellows in sports traumatology, practicing orthopedic surgeons and even high-volume clinicians may benefit "Curbside consultation of ACL". Clinicians other than orthopedic practitioners like physical treatment specialists, sports medicine practitioners, nonphysician medical stuff in sports medicine like physiotherapists and even some curious patients in an extent may benefit this referral. ASSESSMENT In the professional practice of the management in ACL injuries many of us have unanswered questions that are not addressed clearly in classical textbooks, which we use to look for the answers in the advises of experienced colleagues. Now the readers have the chance to get these answers for decision making in complicated cases or in complications from the many experts of ACL surgery. In the form of questions and brief answers to learn the cur-rent concepts from this pitfalls and pearls by most experi-enced authors makes me feeling in a safer side in my practice

Collaborative Chat Reference Service Effectiveness Varies by Question Type for Public Library Patrons. A review of: Kwon, Nahyun. ʺPublic Library Patronsʹ Use of Collaborative Chat Reference Service: The Effectiveness of Question Answering by Question Type.ʺ Library & Information Science Research 29.1 (Mar. 2007: 70‐91.

Directory of Open Access Journals (Sweden)

Stephanie Hall

2008-03-01

Full Text Available Objective – To assess the effectiveness of a collaborative chat reference service in answering different types of question. Specifically, the study compares the degree of answer completion and the level of user satisfaction for simple factual questions vs. more in‐depth subject‐based reference questions, and for ‘local’ (pertaining to a particular library and non‐local questions.Design – Content analysis of 415 transcripts of reference transactions, which were also compared to corresponding user satisfaction survey results.Setting – An online collaborative reference service offered by a large public library system (33 branch and regional locations. This service is part of the Metropolitan Cooperative Library System: a virtual reference consortium of U.S. libraries (public, academic, special, and corporate that provides 24/7 service.Subjects – Reference librarians from around the U.S. (49 different libraries, and users logging into the service via the public library system’s portal (primarily patrons of the 49 libraries. Method – Content analysis was used to evaluate virtual reference transcripts recorded between January and June, 2004. Reliability was enhanced through triangulation, with researchers comparing the content analysis of each transcript against the results of a voluntary exit survey. Of 1,387 transactions that occurred during the period of study, 420 users completed the survey and these formed the basis of the study, apart from 5 transactions that were omitted because the questions were incomprehensible. Questions were examined and assigned to five categories: “simple, factual questions; subject‐based research questions; resource access questions; circulation‐related questions; and local library information inquiries” (80‐81. Answers were classed as either “completely answered, partially answered or unanswered, referred, and problematic endings” (82. Lastly, user satisfaction was surveyed on three

Managing missing scores on the Roland Morris Disability Questionnaire

DEFF Research Database (Denmark)

Lauridsen, Henrik Hein

Background and purpose: It is likely that the most common method for calculating a Roland Morris Disability Index (RMDQ) sum score is to simply ignore any unanswered questions. In contrast, the raw sum score on the Oswestry Disability Index (ODI) is converted to a 0-100 scale, with the advantage...... of unanswered RMDQ questions was measured in a research and a routine care setting. The accuracy of the RMDQ proportional recalculation method was measured using 311 fully completed RMDQ and matching ODI questionnaire sets. Raw sum scores were calculated, and questions systematically dropped. At each stage, sum...

A statistical analysis of student questions in a cell biology laboratory.

Science.gov (United States)

Keeling, Elena L; Polacek, Kelly M; Ingram, Ella L

2009-01-01

Asking questions is an essential component of the practice of science, but question-asking skills are often underemphasized in science education. In this study, we examined questions written by students as they prepared for laboratory exercises in a senior-level cell biology class. Our goals were to discover 1) what types of questions students asked about laboratory activities, 2) whether the types or quality of questions changed over time, and 3) whether the quality of questions or degree of improvement was related to academic performance. We found a majority of questions were about laboratory outcomes or seeking additional descriptive information about organisms or processes to be studied. Few questions earned the highest possible ranking, which required demonstration of extended thought, integration of information, and/or hypotheses and future experiments, although a majority of students asked such a question at least once. We found no correlation between types of student questions or improvement in questions and final grades. Only a small improvement in overall question quality was seen despite considerable practice at writing questions about science. Our results suggest that improving students' ability to generate higher-order questions may require specific pedagogical intervention.

An official American Thoracic Society/European Respiratory Society statement: research questions in COPD

Directory of Open Access Journals (Sweden)

Bartolome R. Celli

2015-06-01

Full Text Available Chronic obstructive pulmonary disease (COPD is a leading cause of morbidity, mortality and resource use worldwide. The goal of this official American Thoracic Society (ATS/European Respiratory Society (ERS Research Statement is to describe evidence related to diagnosis, assessment, and management; identify gaps in knowledge; and make recommendations for future research. It is not intended to provide clinical practice recommendations on COPD diagnosis and management. Clinicians, researchers and patient advocates with expertise in COPD were invited to participate. A literature search of Medline was performed, and studies deemed relevant were selected. The search was not a systematic review of the evidence. Existing evidence was appraised and summarised, and then salient knowledge gaps were identified. Recommendations for research that addresses important gaps in the evidence in all areas of COPD were formulated via discussion and consensus. Great strides have been made in the diagnosis, assessment and management of COPD, as well as understanding its pathogenesis. Despite this, many important questions remain unanswered. This ATS/ERS research statement highlights the types of research that leading clinicians, researchers and patient advocates believe will have the greatest impact on patient-centred outcomes.

Effect of two types of control questions and two question formats on the outcomes of polygraph examinations.

Science.gov (United States)

Horvath, Frank; Palmatier, John J

2008-07-01

Two major variations of polygraph "Control Question" testing, the Zone Comparison (ZoC) and the Modified General Question Test (MGQT) were evaluated. Within each, the type of control question, Exclusive or "time bar" (e.g., "Before you were 21, did you ever...") and Nonexclusive or "no time bar" (e.g., "Did you ever....?") was manipulated in a mock theft scenario, with 80 male and 40 female subjects randomly assigned to be either innocent or guilty. Polygraphic data collected by experienced field examiners were numerically scored by an evaluator blind to all aspects of the study. Decision accuracy was not related to the type of procedure (ZoC/MGQT) used or the subject's sex. Accuracy was significantly related to the type of control question [chi(2) (2) = 11.46, p = 0.003; tau c = 0.29]. Nonexclusive control questions produced greater accuracy than Exclusive control questions on both innocent and guilty subjects. These results and subjects' self-reports support the general "theory" on which control question (CQ) testing is based. The need for better empirical support of accepted dogma and current field practices is strongly indicated by these findings.

VQABQ: Visual Question Answering by Basic Questions

KAUST Repository

Huang, Jia-Hong

2017-03-19

Taking an image and question as the input of our method, it can output the text-based answer of the query question about the given image, so called Visual Question Answering (VQA). There are two main modules in our algorithm. Given a natural language question about an image, the first module takes the question as input and then outputs the basic questions of the main given question. The second module takes the main question, image and these basic questions as input and then outputs the text-based answer of the main question. We formulate the basic questions generation problem as a LASSO optimization problem, and also propose a criterion about how to exploit these basic questions to help answer main question. Our method is evaluated on the challenging VQA dataset and yields state-of-the-art accuracy, 60.34% in open-ended task.

VQABQ: Visual Question Answering by Basic Questions

KAUST Repository

Huang, Jia-Hong; Alfadly, Modar; Ghanem, Bernard

2017-01-01

Taking an image and question as the input of our method, it can output the text-based answer of the query question about the given image, so called Visual Question Answering (VQA). There are two main modules in our algorithm. Given a natural language question about an image, the first module takes the question as input and then outputs the basic questions of the main given question. The second module takes the main question, image and these basic questions as input and then outputs the text-based answer of the main question. We formulate the basic questions generation problem as a LASSO optimization problem, and also propose a criterion about how to exploit these basic questions to help answer main question. Our method is evaluated on the challenging VQA dataset and yields state-of-the-art accuracy, 60.34% in open-ended task.

Questioning in Distributed Product Development Teams: Supporting Shared Understanding

DEFF Research Database (Denmark)

Cash, Philip; Ahmed-Kristensen, Saeema

2015-01-01

globally distributed NPD activities. Poor shared understanding can ultimately result in delays and rework. One major antecedent of shared understanding development is question asking. This work uses a quasiexperimental study to test the impact of questioning support on different types of distributed teams...

Research in thermal biology: Burning questions for coldwater stream fishes

Science.gov (United States)

McCullough, D.A.; Bartholow, J.M.; Jager, H.I.; Beschta, R.L.; Cheslak, E.F.; Deas, M.L.; Ebersole, J.L.; Foott, J.S.; Johnson, S.L.; Marine, K.R.; Mesa, M.G.; Petersen, J.H.; Souchon, Y.; Tiffan, K.F.; Wurtsbaugh, W.A.

2009-01-01

With the increasing appreciation of global warming impacts on ecological systems, in addition to the myriad of land management effects on water quality, the number of literature citations dealing with the effects of water temperature on freshwater fish has escalated in the past decade. Given the many biological scales at which water temperature effects have been studied, and the growing need to integrate knowledge from multiple disciplines of thermal biology to fully protect beneficial uses, we held that a survey of the most promising recent developments and an expression of some of the remaining unanswered questions with significant management implications would best be approached collectively by a diverse research community. We have identified five specific topic areas of renewed research where new techniques and critical thought could benefit coldwater stream fishes (particularly salmonids): molecular, organism, population/species, community and ecosystem, and policy issues in water quality. Our hope is that information gained through examination of recent research fronts linking knowledge at various scales will prove useful in managing water quality at a basin level to protect fish populations and whole ecosystems. Standards of the past were based largely on incipient lethal and optimum growth rate temperatures for fish species, while future standards should consider all integrated thermal impacts to the organism and ecosystem. ?? Taylor and Francis Group, LLC.

Semantic annotation of consumer health questions.

Science.gov (United States)

Kilicoglu, Halil; Ben Abacha, Asma; Mrabet, Yassine; Shooshan, Sonya E; Rodriguez, Laritza; Masterton, Kate; Demner-Fushman, Dina

2018-02-06

Consumers increasingly use online resources for their health information needs. While current search engines can address these needs to some extent, they generally do not take into account that most health information needs are complex and can only fully be expressed in natural language. Consumer health question answering (QA) systems aim to fill this gap. A major challenge in developing consumer health QA systems is extracting relevant semantic content from the natural language questions (question understanding). To develop effective question understanding tools, question corpora semantically annotated for relevant question elements are needed. In this paper, we present a two-part consumer health question corpus annotated with several semantic categories: named entities, question triggers/types, question frames, and question topic. The first part (CHQA-email) consists of relatively long email requests received by the U.S. National Library of Medicine (NLM) customer service, while the second part (CHQA-web) consists of shorter questions posed to MedlinePlus search engine as queries. Each question has been annotated by two annotators. The annotation methodology is largely the same between the two parts of the corpus; however, we also explain and justify the differences between them. Additionally, we provide information about corpus characteristics, inter-annotator agreement, and our attempts to measure annotation confidence in the absence of adjudication of annotations. The resulting corpus consists of 2614 questions (CHQA-email: 1740, CHQA-web: 874). Problems are the most frequent named entities, while treatment and general information questions are the most common question types. Inter-annotator agreement was generally modest: question types and topics yielded highest agreement, while the agreement for more complex frame annotations was lower. Agreement in CHQA-web was consistently higher than that in CHQA-email. Pairwise inter-annotator agreement proved most

Questioning Questions: Elementary Teachers' Adaptations of Investigation Questions Across the Inquiry Continuum

Science.gov (United States)

Biggers, Mandy

2018-02-01

Questioning is a central practice in science classrooms. However, not every question translates into a "good" science investigation. Questions that drive science investigations can be provided by many sources including the teacher, the curriculum, or the student. The variations in the source of investigation questions were explored in this study. A dataset of 120 elementary science classroom videos and associated lesson plans from 40 elementary teachers (K-5) across 21 elementary school campuses were scored on an instrument measuring the amount of teacher-direction or student-direction of the lessons' investigation questions. Results indicated that the investigation questions were overwhelmingly teacher directed in nature, with no opportunities for students to develop their own questions for investigation. This study has implications for researchers and practitioners alike, calling attention to the teacher-directed nature of investigation questions in existing science curriculum materials, and the need for teacher training in instructional strategies to adapt their existing curriculum materials across the continuum of teacher-directed and student-directed investigation questions. Teachers need strategies for adapting the teacher-directed questions provided in their existing curriculum materials in order to allow students the opportunity to engage in this essential scientific practice.

Characteristics of dune-paleosol-sequences in Fuerteventura. - What should be questioned?

Science.gov (United States)

Faust, Dominik; Willkommen, Tobias; Yanes, Yurena; Richter, David; Zöller, Ludwig

2013-04-01

Characteristics of dune-paleosol-sequences in Fuerteventura. - What should be questioned? Dominik Faust, TU Dresden, Germany Tobias Willkommen, TU Dresden, Germany Yurena Yanes, CSIC Granada/Cincinatti, Spain/USA David Richter, TU Dresden, Germany Ludwig Zöller, Uni Bayreuth, Germany The northern part of Fuerteventura is characterized by large dune fields. We investigated dune-paleosol-sequences in four pits to establish a robust stratigraphy and to propose a standard section. An interaction of processes like dune formation, soil formation and redeposition of soils and sand are most important to understand the principles of landscape development in the study area. To our mind a process cycle seem to be important: First climbing-dunes are formed by sand of shelf origin. Then soil formation could have taken place. Soil and/or sand were then eroded and deposited at toe slope position. This material in turn is the source of new sand supply and dune formation. The described cycle may be repeated several times and this ping-pong-process holds on. The results are sections composed of dune layers, paleosols and colluvial material interbedded. Fundamental questions still remain unanswered: Is climate change responsable for changes in process combination (e.g. from dune formation to soil formation)? Or are these features due to divergence phenomenon, where different effects/results (dune and soils) may be linked to similar causes (here: climate)? Assuming that different features (soils and dunes) were formed under one climate, increasing soil forming intensity could be mainly a function of decreasing sand supply. This in turn could be caused by reduced sand production (s. ZECH et al. accepted). However geochemical data and mollusc assemblages point to changing environments in space and even climate modifications in time.

Managing missing scores on the Roland Morris Disability Questionnaire

DEFF Research Database (Denmark)

Lauridsen, Henrik Hein

2009-01-01

systematically dropped from each person’s raw scores and the standardized score was proportionally recalculated. This process was repeated until 6 questions had been dropped from each person’s questionnaire. ·         The error (absolute and percentage) introduced by each level of dropped question was calculated......MANAGING MISSING SCORES ON THE ROLAND MORRIS DISABILITY QUESTIONNAIRE  Peter Kenta and Henrik Hein Lauridsenb  aBack Research Centre and bInstitute of Sports Science and Clinical Biomechanics, University of Southern Denmark Background There is no standard method to calculate Roland Morris...... Disability Questionnaire (RMDQ) sum scores when one or more questions have not been answered. However, missing data are common on the RMDQ and the current options are: calculate a sum score regardless of unanswered questions, reject all data containing unanswered questions, or to impute scores. Other...

Ten questions about systems biology

DEFF Research Database (Denmark)

Joyner, Michael J; Pedersen, Bente K

2011-01-01

to understand how whole animals adapt to the real world. We argue that a lack of fluency in these concepts is a major stumbling block for what has been narrowly defined as 'systems biology' by some of its leading advocates. We also point out that it is a failure of regulation at multiple levels that causes many......In this paper we raise 'ten questions' broadly related to 'omics', the term systems biology, and why the new biology has failed to deliver major therapeutic advances for many common diseases, especially diabetes and cardiovascular disease. We argue that a fundamentally narrow and reductionist...

Ten questions about systems biology

DEFF Research Database (Denmark)

Joyner, Michael J; Pedersen, Bente K

2011-01-01

In this paper we raise 'ten questions' broadly related to 'omics', the term systems biology, and why the new biology has failed to deliver major therapeutic advances for many common diseases, especially diabetes and cardiovascular disease. We argue that a fundamentally narrow and reductionist...... to understand how whole animals adapt to the real world. We argue that a lack of fluency in these concepts is a major stumbling block for what has been narrowly defined as 'systems biology' by some of its leading advocates. We also point out that it is a failure of regulation at multiple levels that causes many...

It's worth the wait: optimizing questioning methods for effective intraoperative teaching.

Science.gov (United States)

Barrett, Meredith; Magas, Christopher P; Gruppen, Larry D; Dedhia, Priya H; Sandhu, Gurjit

2017-07-01

The use of questioning to engage learners is critical to furthering resident education intraoperatively. Previous studies have demonstrated that higher level questioning and optimal wait times (>3 s) result in learner responses reflective of higher cognition and retention. Given the importance of intraoperative learning, we investigated question delivery in the operating room. A total of 12 laparoscopic cholecystectomies were observed and recorded. All questions were transcribed and classified using Bloom's Taxonomy, a framework associated with hierarchical levels of learning outcomes. Wait time between question end and response was recorded. Six faculty attendings and seven house officers at our institution were observed. A total of 133 questions were recorded with an average number of questions per case of 11.2. The majority of questions 112 out of 133 (84%) were classified as Bloom's levels 1-3, with only 6% of questions of the highest level. The wait time before the resident answered the question averaged 1.75 s, with attendings interceding after 2.50 s. Question complexity and wait time did not vary based on resident postgraduate year level suggesting limited tailoring of question to learner. Intraoperative questioning is not aligned with higher level thinking. The majority of questions were Bloom's level 3 or below, limiting the complexity of answer formulation. Most responses were given within 2 s, hindering opportunity to pursue higher-order thinking. This suggests including higher level questions and tailoring questions to learner level may improve retention and maximize gains. In addition, with attendings answering 20% of their own questions, increasing their wait time offers another area for teaching development. © 2017 Royal Australasian College of Surgeons.

Six Significant Questions About Performance and Performance Courses in the Major.

Science.gov (United States)

Lawson, Hal A.; Pugh, D. Lionel

James Bryant Conant's book, "The Education of America" (1963), triggered a major change in physical education curricula. Formerly a (sports) skills and applied techniques oriented discipline, physical education has expanded to areas such as kinesiology and sports sociology. However, performance and performance courses are still an important aspect…

The effects of higher-order questioning strategies on nonscience majors' achievement in an introductory environmental science course and their attitudes toward the environment

Science.gov (United States)

Eason, Grace Teresa

The purpose of this quasi-experimental study was to determine the effect a higher-order questioning strategy (Bloom, 1956) had on undergraduate non-science majors' attitudes toward the environment and their achievement in an introductory environmental science course, EDS 1032, "Survey of Science 2: Life Science," which was offered during the Spring 2000 term. Students from both treatment and control groups (N = 63), which were determined using intact classes, participated in eight cooperative group activities based on the Biological Sciences Curriculum Studies (BSCS) 5E model (Bybee, 1993). The treatment group received a higher-order questioning method combined with the BSCS 5E model. The control group received a lower-order questioning method, combined with the BSCS 5E model. Two instruments were used to measure students' attitude and achievement changes. The Ecology Issue Attitude (EIA) survey (Schindler, 1995) and a comprehensive environmental science final exam. Kolb's Learning Style Inventory (KLSI, 1985) was used to measure students' learning style type. After a 15-week treatment period, results were analyzed using MANCOVA. The overall MANCOVA model used to test the statistical difference between the collective influences of the independent variables on the three dependent variables simultaneously was found to be not significant at alpha = .05. This differs from findings of previous studies in which higher-order questioning techniques had a significant effect on student achievement (King 1989 & 1992; Blosser, 1991; Redfield and Rousseau, 1981; Gall 1970). At the risk of inflated Type I and Type II error rates, separate univariate analyses were performed. However, none of the research factors, when examined collectively or separately, made any significant contribution to explaining the variability in EIA attitude, EIA achievement, and comprehensive environmental science final examination scores. Nevertheless, anecdotal evidence from student's self

Questioning Questions: Elementary Teachers' Adaptations of Investigation Questions across the Inquiry Continuum

Science.gov (United States)

Biggers, Mandy

2018-01-01

Questioning is a central practice in science classrooms. However, not every question translates into a "good" science investigation. Questions that drive science investigations can be provided by many sources including the teacher, the curriculum, or the student. The variations in the source of investigation questions were explored in…

KEMAMPUAN MAHASISWA DALAM MEMBUAT COMPREHENSION QUESTIONS

Directory of Open Access Journals (Sweden)

Pudiyono Pudiyono

2016-10-01

Full Text Available The aims of the research were to find out (a the level of the students’ ability in making comprehension questions, (b the students’ map of problems in making comprehension questions. The population of the research was all students joining Reading 4 academic year 2016, totaling to 30 students, while the sample was taken from all students. The result of data analysis showed that the average ability of the students, with score more than 70 reached 66.66%. In details, only 4 of the samples (13.33% got no wrong answers or an A. Those who got good achievement (B, considered as majority, amounted to 16 students (53.33%. The participants achieving enough grades (C reached 7 students or 23.33%. The last level achieved in this research was D with the number reaching 3 (10%. The map of problems laid on their inability in identifying between yes/no and WH questions, inverted sentence, choosing the right auxiliary and verbs and their spelling ability. Keyword: comprehension, questions, inversion, problem map, ability

Rhetorical questions or rhetorical uses of questions?

Directory of Open Access Journals (Sweden)

Špago Džemal

2016-12-01

Full Text Available This paper aims to explore whether some rhetorical questions contain certain linguistic elements or forms which would differentiate them from answer-eliciting and action-eliciting questions, and thereby hint at their rhetorical nature even outside the context. Namely, despite the fact that the same questions can be rhetorical in one context, and answer-eliciting in another, some of them are more likely to be associated with rhetorical or non-rhetorical use. The analysis is based on extensive data (over 1200 examples of rhetorical questions taken from 30 plays by two British and two American writers, and the results are expected to give an insight into whether we can talk about rhetorical questions or just a rhetorical use of questions.

Assessment, diagnosis, and treatment of HIV-associated neurocognitive disorder: a consensus report of the mind exchange program

NARCIS (Netherlands)

Antinori, Andrea; Arendt, Gabriele; Grant, Igor; Letendre, Scott; Chair, N. N.; Munoz-Moreno, Jose A.; Eggers, Christian; Brew, Bruce; Brouillette, Marie-Josee; Bernal-Cano, Francisco; Carvalhal, Adriana; Christo, Paulo Pereira; Cinque, Paola; Cysique, Lucette; Ellis, Ronald; Everall, Ian; Gasnault, Jacques; Husstedt, Ingo; Korten, Volkan; Machala, Ladislav; Obermann, Mark; Ouakinin, Silvia; Podzamczer, Daniel; Portegies, Peter; Rackstraw, Simon; Rourke, Sean; Sherr, Lorraine; Streinu-Cercel, Adrian; Winston, Alan; Wojna, Valerie; Yazdanpannah, Yazdan; Arbess, Gordon; Baril, Jean-Guy; Begovac, Josip; Bergin, Colm; Bonfanti, Paolo; Bonora, Stefano; Brinkman, Kees; Canestri, Ana; Cholewinska-Szymanska, Grazyna; Chowers, Michal; Cooney, John; Corti, Marcelo; Doherty, Colin; Elbirt, Daniel; Esser, Stefan; Florence, Eric; Force, Gilles; Gill, John; Goffard, Jean-Christophe

2013-01-01

Many practical clinical questions regarding the management of human immunodeficiency virus (HIV)-associated neurocognitive disorder (HAND) remain unanswered. We sought to identify and develop practical answers to key clinical questions in HAND management. Sixty-six specialists from 30 countries

The second language acquisition of French tense, aspect, mood and modality

CERN Document Server

Ayoun, Dalila

2013-01-01

Temporal-aspectual systems have a great potential of informing our understanding of the developing competence of second language learners. So far, the vast majority of empirical studies investigating L2 acquisition have largely focused on past temporality, neglecting the acquisition of the expression of the present and future temporalities with rare exceptions (aside from ESL learners), leaving unanswered the question of how the investigation of different types of temporality may inform our understanding of the acquisition of temporal, aspectual and mood systems as a whole. This monograph addr

The Future of Geomagnetic Storm Predictions: Implications from Recent Solar and Interplanetary Observations

Science.gov (United States)

Tsurutani, B. T.; Gonzalez, W. D.

1995-01-01

Within the last 7-8 years, there has been a substantial growth in out knowledge of the solar and interplanetary causes of geomagnetic storms at Earth. This review article will not attempt to cover all of the work done during this period. This can be found elsewhere. Our emphasis here will be on recent efforts that expose important, presently unanswered questions that must be addressed and solved before true predictability of storms can be possible. Hopefully, this article will encourage some readers to join this effort and perhaps make major contributions to the field.

Do cortical gamma oscillations promote or suppress perception? An under-asked question with an over-assumed answer

Directory of Open Access Journals (Sweden)

William eSedley

2013-09-01

Full Text Available Cortical gamma oscillations occur alongside perceptual processes, and in proportion to perceptual salience. They have a number of properties that make them ideal candidates to explain perception, including incorporating synchronised discharges of neural assemblies, and their emergence over a fast timescale consistent with that of perception. These observations have led to widespread assumptions that gamma oscillations’ role is to cause or facilitate conscious perception (i.e. a ‘positive’ role. While the majority of the human literature on gamma oscillations is consistent with this interpretation, many or most of these studies could equally be interpreted as showing a suppressive or inhibitory (i.e. ‘negative’ role. For example, presenting a stimulus and recording a response of increased gamma oscillations would only suggest a role for gamma oscillations in the representation of that stimulus, and would not specify what that role were. For instance, if gamma oscillations were inhibitory, then they would become selectively activated in response to the stimulus they acted to inhibit.In this review, we consider two classes of gamma oscillations: broadband and narrowband, which have very different properties (and likely roles. We first discuss studies on gamma oscillations that are non-discriminatory, with respect to the role of gamma oscillations, followed by studies that specifically support specifically a positive or negative role. These include work on perception in healthy individuals, and in the pathological contexts of phantom perception and epilepsy. Reference is based as much as possible on magnetoencephalography (MEG and electroencephalography (EEG studies, but we also consider evidence from invasive recordings in humans and other animals. Attempts are made to reconcile findings within a common framework. We conclude with a summary of the pertinent questions that remain unanswered, and suggest how future studies might address

Mobility and language change in real time

DEFF Research Database (Denmark)

Monka, Malene

Diachronic studies of the interrelationship between mobility and language change leave us with some unanswered questions of causation. The most important question is whether language change is caused by mobility, or if mobile informants mark themselves linguistically different than their non-mobi...... mobile and non-mobile informants. I also suggest a human geographic approach to place to explain the differences between the language change of the mobile informants (e.g. Britain 2009; Johnstone 2004).......Diachronic studies of the interrelationship between mobility and language change leave us with some unanswered questions of causation. The most important question is whether language change is caused by mobility, or if mobile informants mark themselves linguistically different than their non......-mobile peers prior to being geographically and socially mobile (e.g. Andersson & Thelander 1994). In the presentation I discuss this question by presenting a real time panel-study of language change in 23 speakers from three municipalities in distinct dialect areas in Denmark. The language change of six mobile...

Uncovering the Genetic History of the Present Day Greenlandic Population

DEFF Research Database (Denmark)

Moltke, Ida; Fumagalli, Matteo; Korneliussen, Thorfinn S

2015-01-01

Because of past limitations in samples and genotyping technologies, important questions about the history of the present-day Greenlandic population remain unanswered. In an effort to answer these questions and in general investigate the genetic history of the Greenlandic population, we analyzed...

Can we share questions? Performance of questions from different question banks in a single medical school.

Science.gov (United States)

Freeman, Adrian; Nicholls, Anthony; Ricketts, Chris; Coombes, Lee

2010-01-01

To use progress testing, a large bank of questions is required, particularly when planning to deliver tests over a long period of time. The questions need not only to be of good quality but also balanced in subject coverage across the curriculum to allow appropriate sampling. Hence as well as creating its own questions, an institution could share questions. Both methods allow ownership and structuring of the test appropriate to the educational requirements of the institution. Peninsula Medical School (PMS) has developed a mechanism to validate questions written in house. That mechanism can be adapted to utilise questions from an International question bank International Digital Electronic Access Library (IDEAL) and another UK-based question bank Universities Medical Assessment Partnership (UMAP). These questions have been used in our progress tests and analysed for relative performance. Data are presented to show that questions from differing sources can have comparable performance in a progress testing format. There are difficulties in transferring questions from one institution to another. These include problems of curricula and cultural differences. Whilst many of these difficulties exist, our experience suggests that it only requires a relatively small amount of work to adapt questions from external question banks for effective use. The longitudinal aspect of progress testing (albeit summatively) may allow more flexibility in question usage than single high stakes exams.

When is a research question not a research question?

Science.gov (United States)

Mayo, Nancy E; Asano, Miho; Barbic, Skye Pamela

2013-06-01

Research is undertaken to answer important questions yet often the question is poorly expressed and lacks information on the population, the exposure or intervention, the comparison, and the outcome. An optimal research question sets out what the investigator wants to know, not what the investigator might do, nor what the results of the study might ultimately contribute. The purpose of this paper is to estimate the extent to which rehabilitation scientists optimally define their research questions. A cross-sectional survey of the rehabilitation research articles published during 2008. Two raters independently rated each question according to pre-specified criteria; a third rater adjudicated all discrepant ratings. The proportion of the 258 articles with a question formulated as methods or expected contribution and not as what knowledge was being sought was 65%; 30% of questions required reworking. The designs which most often had poorly formulated research questions were randomized trials, cross-sectional and measurement studies. Formulating the research question is not purely a semantic concern. When the question is poorly formulated, the design, analysis, sample size calculations, and presentation of results may not be optimal. The gap between research and clinical practice could be bridged by a clear, complete, and informative research question.

Work Values and College Major Choice

Science.gov (United States)

Balsamo, Michela; Lauriola, Marco; Saggino, Aristide

2013-01-01

Our study sought to clarify the nature of the known individual differences in work values associated with academic college major choice, specifically the question whether these precede or follow the choice of an academic major. To rule out environmental influences during academic study, group differences in five value orientations were evaluated…

Questions and Questioning Techniques: A View of Indonesian Students’ Preferences

Directory of Open Access Journals (Sweden)

Debora Tri Ragawanti

2009-01-01

Full Text Available This study investigated students’ preference on teacher’s questions and questionings techniques and more importantly on how they could facilitate or impede their learning. The results on teacher’s questioning techniques showed that random nomination was more preferred than pre-arranged format nomination. In addition, techniques of nominating volunteering students and of giving wait-time were disliked by most student-respondents. As for types of question, the yes/no question was favored by most of the respondents. Different from the yes/no question, the number of respondents leaning forward to the analysis question, questions about fact of life, and questions to state opinion did not show a significant difference from the number of those leaning against the same questions.

Open Innovation Thinking as a Mechanism for Strategic Development of Knowledge Intensive Ventures

DEFF Research Database (Denmark)

Lassen, Astrid Heidemann; McKelvey, Maureen

questions on the specificities hereof remain unanswered. This is the starting point of the current research study. In order to research the identified gap in knowledge, we address the following research question in this paper. How do strategic considerations unfold in the context of knowledge intensive...

Denitrification, nitrification, and atmospheric nitrous oxide

National Research Council Canada - National Science Library

Delwiche, C. C

1981-01-01

In this book, a number of unanswered questions particularly demanding of attention are analyzed to determine the significance of various chemical and biological processes involved with the atmospheric...

Radiation epidemiology: the 'past is prologue' to the twenty-first century

International Nuclear Information System (INIS)

Boice, J.D.

1998-01-01

Although the latter part of the twentieth century has seen major advances in the understanding of radiation effects, there are many questions which remain unanswered. This paper notes the recent advances in radiation epidemiology and discusses the health effects of ionizing radiation from certain occupations, from nuclear exposures (the A-bomb and nuclear accidents), from medical procedures, from radon gas and from environmental radiation. It concludes with a forward look at what the new millennium may bring in terms of improved understanding and clarification of radiation risks, particularly in key areas such as susceptibility and interaction. (author)

Characteristic sizes of life in the oceans - from bacteria to whales

DEFF Research Database (Denmark)

Andersen, Ken Haste; Berge, T.; Goncalves, R.

2016-01-01

-based scaling laws for resource acquisition, mobility, sensory range, and progeny size for all pelagic marine life, from bacteria to whales. Further, we review and develop simple theoretical arguments for observed scaling laws and the characteristic sizes of a change or breakdown of power laws. We divide life...... in the ocean into seven major realms based on trophic strategy, physiology, and life history strategy. Such a categorization represents a move away from a taxonomically oriented description toward a trait-based description of life in the oceans. Finally, we discuss life forms that transgress the simple size......-based rules and identify unanswered questions....

HOW TO GENERATE AUTONOMOUS QUESTIONING IN SECONDARY MATHEMATICS TEACHING?

DEFF Research Database (Denmark)

Jessen, Britta Eyrich

2017-01-01

In mathematics education it is still a major challenge to find ways to nurture students to pose and pursue their own questions in order to learn mathematics. During the last three decades problem posing has been explored through different approaches and in empirical studies. This paper presents...... the result of an empirical study, where teaching was designed and conducted based on The Anthropological Theory of the Didactic. It is shown how a changed didactic contract and open generating questions posed by the teacher can support students’ autonomous questioning of the taught knowledge. In the study......, students developed knowledge that went beyond curriculum requirements through autonomous activities, which were different from more traditional school and pedagogical culture....

Question popularity analysis and prediction in community question answering services.

Science.gov (United States)

Liu, Ting; Zhang, Wei-Nan; Cao, Liujuan; Zhang, Yu

2014-01-01

With the blooming of online social media applications, Community Question Answering (CQA) services have become one of the most important online resources for information and knowledge seekers. A large number of high quality question and answer pairs have been accumulated, which allow users to not only share their knowledge with others, but also interact with each other. Accordingly, volumes of efforts have been taken to explore the questions and answers retrieval in CQA services so as to help users to finding the similar questions or the right answers. However, to our knowledge, less attention has been paid so far to question popularity in CQA. Question popularity can reflect the attention and interest of users. Hence, predicting question popularity can better capture the users' interest so as to improve the users' experience. Meanwhile, it can also promote the development of the community. In this paper, we investigate the problem of predicting question popularity in CQA. We first explore the factors that have impact on question popularity by employing statistical analysis. We then propose a supervised machine learning approach to model these factors for question popularity prediction. The experimental results show that our proposed approach can effectively distinguish the popular questions from unpopular ones in the Yahoo! Answers question and answer repository.

Robustness Analysis of Visual Question Answering Models by Basic Questions

KAUST Repository

Huang, Jia-Hong

2017-11-01

Visual Question Answering (VQA) models should have both high robustness and accuracy. Unfortunately, most of the current VQA research only focuses on accuracy because there is a lack of proper methods to measure the robustness of VQA models. There are two main modules in our algorithm. Given a natural language question about an image, the first module takes the question as input and then outputs the ranked basic questions, with similarity scores, of the main given question. The second module takes the main question, image and these basic questions as input and then outputs the text-based answer of the main question about the given image. We claim that a robust VQA model is one, whose performance is not changed much when related basic questions as also made available to it as input. We formulate the basic questions generation problem as a LASSO optimization, and also propose a large scale Basic Question Dataset (BQD) and Rscore (novel robustness measure), for analyzing the robustness of VQA models. We hope our BQD will be used as a benchmark for to evaluate the robustness of VQA models, so as to help the community build more robust and accurate VQA models.

Robustness Analysis of Visual Question Answering Models by Basic Questions

KAUST Repository

Huang, Jia-Hong

2017-01-01

Visual Question Answering (VQA) models should have both high robustness and accuracy. Unfortunately, most of the current VQA research only focuses on accuracy because there is a lack of proper methods to measure the robustness of VQA models. There are two main modules in our algorithm. Given a natural language question about an image, the first module takes the question as input and then outputs the ranked basic questions, with similarity scores, of the main given question. The second module takes the main question, image and these basic questions as input and then outputs the text-based answer of the main question about the given image. We claim that a robust VQA model is one, whose performance is not changed much when related basic questions as also made available to it as input. We formulate the basic questions generation problem as a LASSO optimization, and also propose a large scale Basic Question Dataset (BQD) and Rscore (novel robustness measure), for analyzing the robustness of VQA models. We hope our BQD will be used as a benchmark for to evaluate the robustness of VQA models, so as to help the community build more robust and accurate VQA models.

Two-Year-Old Children Differentiate Test Questions from Genuine Questions

Science.gov (United States)

Grosse, Gerlind; Tomasello, Michael

2012-01-01

Children are frequently confronted with so-called "test questions". While genuine questions are requests for missing information, test questions ask for information obviously already known to the questioner. In this study we explored whether two-year-old children respond differentially to one and the same question used as either a genuine question…

Poverty and Maternal Responsiveness: The Role of Maternal Stress and Social Resources

Science.gov (United States)

Evans, Gary W.; Boxhill, Louise; Pinkava, Michael

2008-01-01

One of the main reasons poverty is bad for children's development is because it reduces maternal responsiveness. This study addresses a heretofore unanswered question: why do low-income children experience diminished maternal responsiveness compared with their more affluent counterparts? In addition, we examine this question among a largely…

Experimenting with Extinction

Science.gov (United States)

DeSantis, Larisa; DeSantis, Derek

2017-01-01

This article describes a lesson in which high school biology, ecology, environmental science, anatomy, and physiology students can devise hypotheses and test them with scientific data, identify unanswered questions, and design an additional study to answer those questions. This module connects students with exciting research and current science…

Nuclear questions; Le nucleaire en questions

Energy Technology Data Exchange (ETDEWEB)

Berg, Eugene

2012-02-15

Civilian and military nuclear questions fill a multitude of publications these days, especially after the Japanese tsunami and the Fukushima disaster. The author analyses some of them and highlights the links between civil and military nuclear industries, the realities of the nuclear cycle and related industrial questions before concluding on the controversial issue of weapons and their proliferation potential

Priority Questions and Horizon Scanning for Conservation: A Comparative Study

Science.gov (United States)

Kark, Salit; Sutherland, William J.; Shanas, Uri; Klass, Keren; Achisar, Hila; Dayan, Tamar; Gavrieli, Yael; Justo-Hanani, Ronit; Mandelik, Yael; Orion, Nir; Pargament, David; Portman, Michelle; Reisman-Berman, Orna; Safriel, Uriel N.; Schaffer, Gad; Steiner, Noa; Tauber, Israel; Levin, Noam

2016-01-01

Several projects aimed at identifying priority issues for conservation with high relevance to policy have recently been completed in several countries. Two major types of projects have been undertaken, aimed at identifying (i) policy-relevant questions most imperative to conservation and (ii) horizon scanning topics, defined as emerging issues that are expected to have substantial implications for biodiversity conservation and policy in the future. Here, we provide the first overview of the outcomes of biodiversity and conservation-oriented projects recently completed around the world using this framework. We also include the results of the first questions and horizon scanning project completed for a Mediterranean country. Overall, the outcomes of the different projects undertaken (at the global scale, in the UK, US, Canada, Switzerland and in Israel) were strongly correlated in terms of the proportion of questions and/or horizon scanning topics selected when comparing different topic areas. However, some major differences were found across regions. There was large variation among regions in the percentage of proactive (i.e. action and response oriented) versus descriptive (non-response oriented) priority questions and in the emphasis given to socio-political issues. Substantial differences were also found when comparing outcomes of priority questions versus horizon scanning projects undertaken for the same region. For example, issues related to climate change, human demography and marine ecosystems received higher priority as horizon scanning topics, while ecosystem services were more emphasized as current priority questions. We suggest that future initiatives aimed at identifying priority conservation questions and horizon scanning topics should allow simultaneous identification of both current and future priority issues, as presented here for the first time. We propose that further emphasis on social-political issues should be explicitly integrated into future

Treatment of "Battlefield Detainees" in the War on Terrorism

National Research Council Canada - National Science Library

Elsea, Jennifer K

2006-01-01

.... court has jurisdiction to hear petitions for "habeas corpus" on behalf of the detainees because they are aliens detained abroad, but left questions involving prisoners' rights and status unanswered...

Treatment of "Battlefield Detainees" in the War on Terrorism

National Research Council Canada - National Science Library

Elsea, Jennifer K

2006-01-01

.... court has jurisdiction to hear petitions for habeas corpus on behalf of the detainees because they are aliens detained abroad, but left questions involving prisoners rights and status unanswered...

Treatment of Battlefield Detainees in the War on Terrorism

National Research Council Canada - National Science Library

Elsea, Jennifer

2005-01-01

.... court has jurisdiction to hear petitions for habeas corpus on behalf of the detainees because they are aliens detained abroad, but left questions involving prisoners rights and status unanswered...

Treatment of "Battlefield Detainees" in the War on Terrorism

National Research Council Canada - National Science Library

Elsea, Jennifer

2005-01-01

.... court has jurisdiction to hear petitions for habeas corpus on behalf of the detainees because they are aliens detained abroad, but left questions involving prisoners' rights and status unanswered...

Treatment of 'Battlefield Detainees' in the War on Terrorism

National Research Council Canada - National Science Library

Elsea, Jennifer K

2007-01-01

.... court has jurisdiction to hear petitions for habeas corpus on behalf of the detainees because they are aliens detained abroad, but left questions involving prisoners rights and status unanswered...

Some of the most interesting things we know, and don't know, about the biochemistry and physiology of elasmobranch fishes (sharks, skates and rays).

Science.gov (United States)

Ballantyne, James S

2016-09-01

The urea-retaining strategy of elasmobranchs has shaped their biochemistry and physiology; from their metabolic organization to the structure of their membranes. It has also affected their capacity to live in freshwater. Although much new information has been uncovered in the past 30years, many unanswered questions remain. These include: a) why was urea selected as the major organic osmolyte, b) why is glutamine used as a nitrogen donor, c) why was plasma albumin lost in marine elasmobranchs, d) what membranes are involved in urea retention in the gills, e) how do urea and trimethylamine N-oxide (TMAO) affect membranes, and f) why retain urea in freshwater. Hypotheses are presented for future investigations but some questions may require a time machine to answer. Copyright © 2016 Elsevier Inc. All rights reserved.

The future of the oceans past: towards a global marine historical research initiative.

Science.gov (United States)

Schwerdtner Máñez, Kathleen; Holm, Poul; Blight, Louise; Coll, Marta; MacDiarmid, Alison; Ojaveer, Henn; Poulsen, Bo; Tull, Malcolm

2014-01-01

Historical research is playing an increasingly important role in marine sciences. Historical data are also used in policy making and marine resource management, and have helped to address the issue of shifting baselines for numerous species and ecosystems. Although many important research questions still remain unanswered, tremendous developments in conceptual and methodological approaches are expected to contribute to a comprehensive understanding of the global history of human interactions with life in the seas. Based on our experiences and knowledge from the "History of Marine Animal Populations" project, this paper identifies the emerging research topics for future historical marine research. It elaborates on concepts and tools which are expected to play a major role in answering these questions, and identifies geographical regions which deserve future attention from marine environmental historians and historical ecologists.

The Complex Chemistry of Embedded Protostars

DEFF Research Database (Denmark)

Lykke, Julie Maria

- or molecular astrophysics - has evolved fast in recent years, due to major technological advancements for radio telescopes. But some of the most central questions still remain unanswered: how, where and when are complex organic molecules formed around young stars? How complex can these molecules become......? Is there a difference in the chemistry for high- and low-mass protostars? The work in this thesis aim to provide answer for these questions by searching for molecules where they have not been detected before and by comparing the relative abundance of different molecules to models and laboratory work as well as between......- and low-mass sources. Modified models and laboratory work as well as more observations are therefore needed to further develop our understanding of the chemistry occurring in star-forming regions....

Can multiple-choice questions simulate free-response questions?

OpenAIRE

Lin, Shih-Yin; Singh, Chandralekha

2016-01-01

We discuss a study to evaluate the extent to which free-response questions could be approximated by multiple-choice equivalents. Two carefully designed research-based multiple-choice questions were transformed into a free-response format and administered on the final exam in a calculus-based introductory physics course. The original multiple-choice questions were administered in another similar introductory physics course on final exam. Findings suggest that carefully designed multiple-choice...

Relationships of Stress Exposures to Health in Gulf War Veterans

National Research Council Canada - National Science Library

Fairbank, John

2000-01-01

Research on Gulf War (GW) illnesses leaves many questions unanswered about diagnostic syndromes of GW illnesses, dimensions of stressor exposures encountered by GW veterans, relations among stressor exposures and GW syndromes...

Relationship of Stress Exposure to Health in Gulf War Veterans

National Research Council Canada - National Science Library

Fairbank, John

2002-01-01

Research on Gulf War (GW) illnesses leaves many questions unanswered about diagnostic syndromes of GW illnesses, dimensions of stressor exposures encountered by GW veterans, relations among stressor exposures and GW syndromes...

Questions that calls for a genius

CERN Multimedia

McKie, Robin

2006-01-01

"Last week an eccentric Russian was tipped to win a "Maths Nobel" for solving the fiendishly difficult Poincare Conjecture, one of seven major "millennium" mathematical mysteries that have been earmarked for urgent solution. But these problems are just the tip of a scientific iceberg. Other fields are also beset by frustrating theoretical failures. Here Robin McKie highlights the most baffing of those questions and suggests how science will one day provide those elusive answers." (1 page)

Four Questions

Science.gov (United States)

Hark-Weber, Amara G., Ed.

2013-01-01

The author is pleased to introduce a new section in "TAJ," Four Questions. The structure is simple: four questions are asked to teaching artists working in various media and locations. The questions are always the same, but because each teaching artist's approach is unique, their answers will provide an insight into particular methodologies that…

On pseudorandom generators in NC⁰

DEFF Research Database (Denmark)

Cryan, Mary; Miltersen, Peter Bro

2001-01-01

In this paper we consider the question of whether NC 0 circuits can generate pseudorandom distributions. While we leave the general question unanswered, we show – • Generators computed by NC 0 circuits where each output bit depends on at most 3 input bits (i.e, DNC 3 0 circuits) and with stretch ...

Alexithymia and the processing of emotional facial expressions (EFEs: systematic review, unanswered questions and further perspectives.

Directory of Open Access Journals (Sweden)

Delphine Grynberg

Full Text Available Alexithymia is characterized by difficulties in identifying, differentiating and describing feelings. A high prevalence of alexithymia has often been observed in clinical disorders characterized by low social functioning. This review aims to assess the association between alexithymia and the ability to decode emotional facial expressions (EFEs within clinical and healthy populations. More precisely, this review has four main objectives: (1 to assess if alexithymia is a better predictor of the ability to decode EFEs than the diagnosis of clinical disorder; (2 to assess the influence of comorbid factors (depression and anxiety disorder on the ability to decode EFE; (3 to investigate if deficits in decoding EFEs are specific to some levels of processing or task types; (4 to investigate if the deficits are specific to particular EFEs. Twenty four studies (behavioural and neuroimaging were identified through a computerized literature search of Psycinfo, PubMed, and Web of Science databases from 1990 to 2010. Data on methodology, clinical characteristics, and possible confounds were analyzed. The review revealed that: (1 alexithymia is associated with deficits in labelling EFEs among clinical disorders, (2 the level of depression and anxiety partially account for the decoding deficits, (3 alexithymia is associated with reduced perceptual abilities, and is likely to be associated with impaired semantic representations of emotional concepts, and (4 alexithymia is associated with neither specific EFEs nor a specific valence. These studies are discussed with respect to processes involved in the recognition of EFEs. Future directions for research on emotion perception are also discussed.

Sexuality Information Needs of Latino and African American Ninth Graders: A Content Analysis of Anonymous Questions

Science.gov (United States)

Angulo-Olaiz, Francisca; Goldfarb, Eva S.; Constantine, Norman A.

2014-01-01

This study used qualitative content analysis to examine anonymous questions about sex and sexuality submitted by Latino and African American adolescents in Los Angeles, California, classrooms. The majority of questions asked about sexuality and sexual behavior, or anatomy and physiology, with fewer questions about pregnancy and pregnancy…

Phrasal Paraphrase Based Question Reformulation for Archived Question Retrieval.

Directory of Open Access Journals (Sweden)

Yu Zhang

Full Text Available Lexical gap in cQA search, resulted by the variability of languages, has been recognized as an important and widespread phenomenon. To address the problem, this paper presents a question reformulation scheme to enhance the question retrieval model by fully exploring the intelligence of paraphrase in phrase-level. It compensates for the existing paraphrasing research in a suitable granularity, which either falls into fine-grained lexical-level or coarse-grained sentence-level. Given a question in natural language, our scheme first detects the involved key-phrases by jointly integrating the corpus-dependent knowledge and question-aware cues. Next, it automatically extracts the paraphrases for each identified key-phrase utilizing multiple online translation engines, and then selects the most relevant reformulations from a large group of question rewrites, which is formed by full permutation and combination of the generated paraphrases. Extensive evaluations on a real world data set demonstrate that our model is able to characterize the complex questions and achieves promising performance as compared to the state-of-the-art methods.

Questioning care at the end of life.

Science.gov (United States)

Ruopp, Patricia; Good, Mary-Jo Delvecchio; Lakoma, Matthew; Gadmer, Nina M; Arnold, Robert M; Block, Susan D

2005-06-01

The goal of the larger study was to explore physicians' emotional responses to the death of their patients; this study analyzed a subset of physician transcripts to elucidate the construct of questioning care, which emerged from the larger study. To analyzes how physicians question care-expressing concern, unease, or uncertainty about treatment decisions and practices, errors, or adverse events-as they attend dying patients. Retrospective interview study of physicians caring for randomly selected deaths on the medical service of a major academic teaching hospital, using qualitative and quantitative measures. SETTING, SUBJECTS: 188 attendings, residents, and interns on the internal medical services of two academic medical centers were part of the larger study. A subsample of 75 physician narratives was selected for qualitative data analysis for this study. Qualitative measures included open-ended questions eliciting physicians' stories of the most recent and a most emotionally powerful patient death they have experienced. Grounded theory was used to analyze physician narratives. Quantitative instruments measured physician attitudes toward end-of-life care and responses to the most recent and most emotional patient death. Physicians question care more frequently in most emotional deaths (42%) than in most recent deaths (34%). Physicians question communication with patients and families and within medical teams, medical judgment and technique, standards of practice, and high-risk treatments, often assigning responsibility for medical management they perceive as inappropriate, futile, overly aggressive, or mistakes in judgment and technique. Responsibility ranges from the distal (the culture of medicine) to the proximal (personal). Frustration, guilt, and anger are more frequently expressed in these narratives when care is questioned. A typology of questioning care emerged from these physicians' narratives that parallels and reflects recent and classic research on

Browse Title Index

African Journals Online (AJOL)

Items 801 - 850 of 3286 ... ... thyroid tissue: unusual differential diagnosis of cervical paraganglioma, Abstract PDF ... clinical settings: important questions unanswered, Abstract PDF ... on the control of Highly Pathogenic Avian Influenza in Nigeria ...

A questions-based investigation of consumer mental-health information

Science.gov (United States)

Kart, Joyce Brothers

2015-01-01

Despite the wealth of mental-health information available online to consumers, research has shown that the mental-health information needs of consumers are not being met. This study contributes to that research by soliciting consumer questions directly, categorizing them, analyzing their form, and assessing the extent to which they can be answered from a trusted and vetted source of online information, namely the website of the US National Institute of Mental Health (NIMH). As an alternative to surveys and analyses of online activity, this study shows how consumer questions provide new insight into what consumers do not know and how they express their information needs. The study crowdsourced 100 consumer questions through Amazon Inc.’s Mechanical Turk. Categorization of the questions shows broad agreement with earlier studies in terms of the content of consumer questions. It also suggests that consumers’ grasp of mental health issues may be low compared to other health topics. The majority of the questions (74%) were simple in form, with the remainder being multi-part, multifaceted or narrative. Even simple-form questions could, however, have complex interpretations. Fifty four questions were submitted to the search box at the NIMH website. For 32 questions, no answer could be found in the top one to three documents returned. Inadequacies in the search and retrieval technology deployed at websites account for some of the failure to find answers. The nature of consumer questions in mental health also plays a role. A question that has a false presupposition is less likely to have an answer in trusted and vetted sources of information. Consumer questions are also expressed with a degree of specificity that makes the retrieval of relevant information difficult. The significance of this study is that it shows what an analysis of consumer mental-health questions can tell us about consumer information needs and it provides new insight into the difficulties facing

Theory of Compliance: Indicator Checklist Statistical Model and Instrument Based Program Monitoring Information System.

Science.gov (United States)

Fiene, Richard J.; Woods, Lawrence

Two unanswered questions about child care are: (1) Does compliance with state child care regulations have a positive impact on children? and (2) Have predictors of program quality been identified? This paper explores a research study and related model that have had some success in answering these questions. Section I, a general introduction,…

Dream machine hopes for a giant collider lie in a worldwide appeal

CERN Multimedia

Appell, D

2004-01-01

"High-energy physicists have a new machine in mind: an unprecedented accelerator 30 kilometers long that would offer a precise tool to explore some of the most imprtant unanswered questions in physics" (1 page)

Relationships of Stress Exposures to Health in Gulf War Veterans

National Research Council Canada - National Science Library

Fairbank, John

2003-01-01

Research on Gulf War (6W) illnesses leaves many questions unanswered about diagnostic syndromes of 6W illnesses, dimensions of stressor exposures encountered by 6W veterans, relations among stressor exposures and GW syndromes...

Living with a Star: New Opportunities in Sun-Climate Research

Science.gov (United States)

Eddy, John Allen

2003-01-01

Enormous advances have been made in the last quarter century in all of these needed areas, covering the two essential halves of the Sun-Climate question: in what we know of solar variations and, equally important, in what we know of the climate system and of climatic changes. These research achievements allow us to examine all aspects of the question more directly and quantitatively than was ever possible before, and in the brighter light and more objective context of other known or suspected climate change mechanisms, including human-induced global greenhouse warming. Brief summaries of present status and current understanding are given below for nine facets of Sun-Climate science in which major progress has been made in recent years. At the same time it will be seen that in every instance, significant elements of uncertainty still remain, Some of the most important of these unanswered questions are considered later, in Section IV.

Understanding Food Allergy | NIH MedlinePlus the Magazine

Science.gov (United States)

... contents Understanding Food Allergy Follow us Understanding Food Allergy Latest Updates from NIH Food allergies are often ... to diagnose, prevent, and treat the disease.” Food allergy studies With so many unanswered questions surrounding food ...

One voice or different choice?: Vote defection of European Union member states in the United Nations General Assembly

DEFF Research Database (Denmark)

Burmester, Nicolas; Jankowski, Michael

2018-01-01

Existing research suggests that European Union member states are increasingly able to act in concert in the United Nations General Assembly. Based on several hundred co-ordination meetings per year, the European Union ‘speaks with one voice’ on most of the resolutions voted upon in the United...... Nations General Assembly. However, little is known about instances where the European Union member states do not vote coherently. Three questions remain unanswered. First, which aspects affect deviating voting behaviour of European Union member states? Second, who are the most frequent defectors from...... the European Union’s majority position? Third, which voting blocs within the European Union can be identified? The article answers these questions in a quantitative design by controlling for domestic factors, issues of resolutions and the position of the United States. The results suggest that domestic aspects...

Executive summary of the 12th HHT international scientific conference.

Science.gov (United States)

Andrejecsk, Jillian W; Hosman, Anna E; Botella, Luisa M; Shovlin, Claire L; Arthur, Helen M; Dupuis-Girod, Sophie; Buscarini, Elisabetta; Hughes, Christopher C W; Lebrin, Franck; Mummery, Christine L; Post, Marco C; Mager, Johannes J

2018-02-01

Hereditary hemorrhagic telangiectasia is an autosomal dominant trait affecting approximately 1 in 5000 people. A pathogenic DNA sequence variant in the ENG, ACVRL1 or SMAD4 genes, can be found in the majority of patients. The 12th International Scientific HHT Conference was held on June 8-11, 2017 in Dubrovnik, Croatia to present and discuss the latest scientific achievements, and was attended by over 200 scientific and clinical researchers. In total 174 abstracts were accepted of which 58 were selected for oral presentations. This article covers the basic science and clinical talks, and discussions from three theme-based workshops. We focus on significant emergent themes and unanswered questions. Understanding these topics and answering these questions will help to define the future of HHT research and therapeutics, and ultimately bring us closer to a cure.

Comments on topical questions of nuclear energy

International Nuclear Information System (INIS)

Butz, H.; Noll, M.

1978-05-01

During the 7th legislative period (1972/76) of the German Bundestag the Federal Government has repeatedly commented on questions concerning nuclear energy. The present documentation comprises a selection of the most important issues. The collection contains in particular: written and oral answers of the Federal Government to written or oral questions of members of parliament; answers of the Federal Government to major and minor interpellations of fractions or factions; statements of the chancellor, the ministers and permanent secretaries; bills of the Federal Government if they were issued as parliamentary documents or as plenary minutes. The main attention when selecting the documents was drawn to giving complete recording of the statements on the safety of nuclear plants and on radiation protection. Furthermore, the comments on questions concerning nuclear energy were considered both in general and in connection with alternative energy sources. Eventually, the general situation concerning energy could be verified. The selection of documents has certainly not thoroughly remained uninfluenced by subjective decisions. The parliamentary documents and plenary minutes given here are recorded by chronological order. An index of subject headings will facilitate access to all documents. (orig.) 891 HP [de

Algorithmic, LOCS and HOCS (chemistry) exam questions: performance and attitudes of college students

Science.gov (United States)

Zoller, Uri

2002-02-01

The performance of freshmen biology and physics-mathematics majors and chemistry majors as well as pre- and in-service chemistry teachers in two Israeli universities on algorithmic (ALG), lower-order cognitive skills (LOCS), and higher-order cognitive skills (HOCS) chemistry exam questions were studied. The driving force for the study was an interest in moving science and chemistry instruction from an algorithmic and factual recall orientation dominated by LOCS, to a decision-making, problem-solving and critical system thinking approach, dominated by HOCS. College students' responses to the specially designed ALG, LOCS and HOCS chemistry exam questions were scored and analysed for differences and correlation between the performance means within and across universities by the questions' category. This was followed by a combined student interview - 'speaking aloud' problem solving session for assessing the thinking processes involved in solving these types of questions and the students' attitudes towards them. The main findings were: (1) students in both universities performed consistently in each of the three categories in the order of ALG > LOCS > HOCS; their 'ideological' preference, was HOCS > algorithmic/LOCS, - referred to as 'computational questions', but their pragmatic preference was the reverse; (2) success on algorithmic/LOCS does not imply success on HOCS questions; algorithmic questions constitute a category on its own as far as students success in solving them is concerned. Our study and its results support the effort being made, worldwide, to integrate HOCS-fostering teaching and assessment strategies and, to develop HOCS-oriented science-technology-environment-society (STES)-type curricula within science and chemistry education.

Questions and answers based on revised 10 CFR Part 20

International Nuclear Information System (INIS)

Borges, T.; Stafford, R.S.; Lu, P.Y.; Carter, D.

1994-05-01

NUREG/CR-6204 is a collection of questions and answers that were originally issued in seven sets and which pertain to revised 10 CFR Part 20. The questions came from both outside and within the NRC. The answers were compiled and provided by NRC staff within the offices of Nuclear Reactor Regulation, Nuclear Material Safety and Safeguards, Nuclear Regulatory Research, the Office of State Programs, and the five regional offices. Although all of the questions and answers have been reviewed by attorneys in the NRC Office of the General Counsel, they do not constitute official legal interpretations relevant to revised 10 CFR Part 20. The questions and answers do, however, reflect NRC staff decisions and technical options on aspects of the revised 10 CFR Part 20 regulatory requirements. This NUREG is being made available to encourage communication among the public, industry, and NRC staff concerning the major revisions of the NRC's standards for protection against radiation

Beyond the Standard Model (2/5)

CERN Multimedia

CERN. Geneva

2000-01-01

After a critical discussion of the questions left unanswered by the Standard Model, I will review the main attemps to construct new theories. In particular, I will discuss grand unification, supersymmetry, technicolour, and theories with extra dimensions.

Beyond the Standard Model (5/5)

CERN Multimedia

CERN. Geneva

2000-01-01

After a critical discussion of the questions left unanswered by the Standard Model, I will review the main attemps to construct new theories. In particular, I will discuss grand unification, supersymmetry, technicolour, and theories with extra dimensions.

Beyond the Standard Model (3/5)

CERN Multimedia

CERN. Geneva

2000-01-01

After a critical discussion of the questions left unanswered by the Standard Model, I will review the main attemps to construct new theories. In particular, I will discuss grand unification, supersymmetry, technicolour, and theories with extra dimensions.

Beyond the Standard Model (4/5)

CERN Multimedia

CERN. Geneva

2000-01-01

After a critical discussion of the questions left unanswered by the Standard Model, I will review the main attemps to construct new theories. In particular, I will discuss grand unification, supersymmetry, technicolour, and theories with extra dimensions.

Beyond the Standard Model (1/5)

CERN Multimedia

CERN. Geneva

2000-01-01

After a critical discussion of the questions left unanswered by the Standard Model, I will review the main attemps to construct new theories. In particular, I will discuss grand unification, supersymmetry, technicolour, and theories with extra dimensions.

Comedy workshop: an enjoyable way to develop multiple-choice questions.

Science.gov (United States)

Droegemueller, William; Gant, Norman; Brekken, Alvin; Webb, Lynn

2005-01-01

To describe an innovative method of developing multiple-choice items for a board certification examination. The development of appropriate multiple-choice items is definitely more of an art, rather than a science. The comedy workshop format for developing questions for a certification examination is similar to the process used by comedy writers composing scripts for television shows. This group format dramatically diminishes the frustrations faced by an individual question writer attempting to create items. The vast majority of our comedy workshop participants enjoy and prefer the comedy workshop format. It provides an ideal environment in which to teach and blend the talents of inexperienced and experienced question writers. This is a descriptive article, in which we suggest an innovative process in the art of creating multiple-choice items for a high-stakes examination.

Report on approaches to predicting probability of cyanobacteria blooms or related indices based on nutrient inputs and other ecosystem attributes in lakes

Science.gov (United States)

Despite a lengthy history of research on cyanobacteria, many important questions about this diverse group of aquatic, photosynthetic “blue-green algae” remain unanswered. For example, how can we more accurately predict cyanobacteria blooms in freshwater systems? Whi...

Personality, academic majors and performance

DEFF Research Database (Denmark)

Vedel, Anna; Thomsen, Dorthe Kirkegaard; Larsen, Lars

2015-01-01

Personality–performance research typically uses samples of psychology students without questioning their representativeness. The present article reports two studies challenging this practice. Study 1: group differences in the Big Five personality traits were explored between students (N = 1067......) in different academic majors (medicine, psychology, law, economics, political science, science, and arts/humanities), who were tested immediately after university enrolment. Study 2: six and a half years later the students’ academic records were obtained, and predictive validity of the Big Five personality...... traits and their subordinate facets was examined in the various academic majors in relation to Grade Point Average (GPA). Significant group differences in all Big Five personality traits were found between students in different academic majors. Also, variability in predictive validity of the Big Five...

Major depressive disorder as a co-morbid diagnosis in ...

African Journals Online (AJOL)

The purpose of this article is to focus on the importance of depressive symptoms in patients suffering from schizophrenia, and the dilemma posed by hierarchical classification methods, which exclude co-morbid diagnoses such as Major Depressive Disorder in patients with schizophrenia. The question arises that if Major ...

Socratic Questioning-Guided Discovery

Directory of Open Access Journals (Sweden)

M. Hakan Türkçapar

2012-04-01

Full Text Available “Socratic Method” is a way of teaching philosophical thinking and knowledge by asking questions which was used by antique period greek philosopher Socrates. Socrates was teaching knowledge to his followers by asking questions and the conversation between them was named “Socratic Dialogues”. In this meaning, no novel knowledge is taught to the individual but only what is formerly known is reminded and rediscovered. The form of socratic questioning which is used during the process of cognitive behavioral therapy is known as Guided Discovery. In this method it is aimed to make the client notice the piece of knowledge which he could notice but is not aware with a series of questions. Socratic method or guided discovery consists of several steps which are: Identifying the problem by listening to the client and making reflections, finding alternatives by examining and evaluating, reidentification by using the newly found information and questioning the old distorted belief and reaching to a conclusion and applying it. Question types used during these procedures are, questions for gaining information, questions revealing the meanings, questions revealing the beliefs, questions about behaviours during the similar past experiences, analyse questions and analytic synthesis questions. In order to make the patient feel understood it is important to be empathetic and summarising the problem during the interview. In this text, steps of Socratic Questioning-Guided Discovery will be reviewed with sample dialogues after eachstep. [JCBPR 2012; 1(1.000: 15-20

Challenges and Pitfalls in the Management of Phenylketonuria

NARCIS (Netherlands)

Feillet, Francois; van Spronsen, Francjan J.; MacDonald, Anita; Trefz, Friedrich K.; Demirkol, Muebeccel; Giovannini, Marcello; Belanger-Quintana, Amaya; Blau, Nenad

Despite recent advances in the management of phenylketonuria and hyperphenylalaninemia, important questions on the management of this disorder remain unanswered. Consensus exists on the need for neonatal screening and early treatment, yet disagreement persists over threshold levels of blood

Baseline and lifetime alcohol consumption and risk of differentiated thyroid carcinoma in the EPIC study

NARCIS (Netherlands)

Sen, Abhijit; Tsilidis, Konstantinos K.; Allen, Naomi E.; Rinaldi, Sabina; Appleby, Paul N.; Almquist, Martin; Schmidt, Julie A.; Dahm, Christina C.; Overvad, Kim; Tjønneland, Anne; Rostgaard-Hansen, Agnetha L.; Clavel-Chapelon, Françoise; Baglietto, Laura; Boutron-Ruault, Marie Christine; Kühn, Tilman; Katze, Verena A.; Boeing, Heiner; Trichopoulou, Antonia; Tsironis, Christos; Lagiou, Pagona; Palli, Domenico; Pala, Valeria; Panico, Salvatore; Tumino, Rosario; Vineis, Paolo; Bueno-de-Mesquita, H. B.; Peeters, Petra H.; Hjartåker, Anette; Lund, Eiliv; Weiderpass, Elisabete; Quirós, J. Ramón; Agudo, Antonio; Sánchez, María José; Arriola, Larraitz; Gavrila, Diana; Gurrea, Aurelio Barricarte; Tosovic, Ada; Hennings, Joakim; Sandström, Maria; Romieu, Isabelle; Ferrari, Pietro; Zamora-Ros, Raul; Khaw, Kay Tee; Wareham, Nicholas J.; Riboli, Elio; Gunter, Marc; Franceschi, Silvia

2015-01-01

Background: Results from several cohort and case-control studies suggest a protective association between current alcohol intake and risk of thyroid carcinoma, but the epidemiological evidence is not completely consistent and several questions remain unanswered. Methods: The association between

Age-related changes in the mitochondrial proteome of the fungus Podospora anserina analyzed by 2D-DIGE and LC-MS/MS

NARCIS (Netherlands)

Chimi, M.A.; Drose, S.; Wittig, I.; Heide, H.; Steger, M.; Werner, A.; Hamann, A.; Osiewacz, H.D.; Brandt, U.

2013-01-01

Many questions concerning the molecular processes during biological aging remain unanswered. Since mitochondria are central players in aging, we applied quantitative two-dimensional difference gel electrophoresis (2D-DIGE) coupled to protein identification by mass spectrometry to study the

Framework for Entrepreneurship Education in Nigerian Higher ...

African Journals Online (AJOL)

... aforementioned unending debates and unanswered questions; and advance the need for entrepreneurial education in Nigerian higher institutions of learning by reviewing and synthesizing available entrepreneurship education literature. The paper concludes that entrepreneurship education initiative is ideal for Nigeria, ...

The Majority of Library Clients Still Use Person-to-Person Interaction When Asking Reference Questions. A review of: De Groote, Sandra L. “Questions Asked at the Virtual and Physical Health Sciences Reference Desk: How Do They Compare and What Do They Tell Us?” Medical Reference Services Quarterly 24.2 (Summer 2005: 11-23.

Directory of Open Access Journals (Sweden)

Suzanne Pamela Lewis

2006-03-01

/staff. undergarduate student, graduate student, non0UIC, unknown; mode of submission (email, chat, phone, in person; and type of question asked (directional, ready reference, in-depth/mediated, instructional, technical, accounts/status and other. In subsequent analysis, the original seven types of questions were further broken down into 19 categories. Main results - It was not possible to undertake a meta-analysis or systematic review of the studies identified in the literature review because of differences in time frames, settings and the categories used to code reference questions. However the following trends emerged: directional questions accounted for between 30 and 35% of questions asked at both the physical and virtual reference desks; the remainder of questions were generally about known item searched, library policies and services, research, dadabase use and quick reference. The statistics collected at UIC Library of the Health Sciences over the period July 1997 to June 2003 were analyzed. Coded reference questions fell into one of four categories; ready reference, in-depth reference, mediated searched and digital reference. There was a noticeable drop in the number of reference questions received in 1999/2000 which reflects trends reported in some of the studies identified in the literature review. The number of mediated searches decreased from 154 in 1997-98 to 4 in 2002/2003, but the number of digital reference questions increased from 0 to 508 in the same period. Statistics were collected over the month of November 2003 for 939 questions asked at the reference and information desks which included: 38 email; 48 chat; 156 phone; and 697 in person. The major findings were as follows: - appoximately 55% of questions were reference questions (33.5% ready reference, 9.7% in-depth/mediated, 9.7% instructional; 30% were directional; and 10% were technical; it is not stated what the remaining 5% of questions were; - library clients who asked the questions comprised graduate

Beginning EFL Teachers' Beliefs about Quality Questions and Their Questioning Practices

Science.gov (United States)

Pham, Ly Ngoc Khanh; Hamid, M. Obaidul

2013-01-01

Motivated by the scarcity of research that examines the impact of teacher beliefs on their actual practices in Vietnam, this study investigated the relationship between teachers' beliefs about quality questions and their questioning behaviours in terms of questioning purposes, content focus, students' cognitive level, wording and syntax. Thirteen…

Is fasting leptin associated with insulin resistance among nondiabetic individuals? The Miami Community Health Study

DEFF Research Database (Denmark)

Donahue, R P; Prineas, R J; Donahue, R D

1999-01-01

Whether serum leptin levels are associated with insulin resistance independent of the effects of hyperinsulinemia and adiposity is an important unanswered question. We examined the relationship between the rate of insulin-mediated glucose uptake and serum leptin concentrations among nondiabetic men...

Universality in Nonaqueous Alkali Oxygen Reduction on Metal Surfaces: Implications for Li−O₂ and Na−O₂ Batteries

DEFF Research Database (Denmark)

Krishnamurthy, Dilip; Hansen, Heine Anton; Viswanathan, Venkatasubramanian

2016-01-01

Nonaqueous metal−oxygen batteries, particularly lithium−oxygen and sodium−oxygen, have emerged as possible high energy density alternatives to Li-ion batteries that could address the limited driving range issues faced by electric vehicles. Many fundamental questions remain unanswered, including t...

The University and Morality: A Revised Approach to University Autonomy and Its Limits.

Science.gov (United States)

Alexander, Jeffrey C.

1986-01-01

The "critical" and "established" positions on university morality leave important questions unanswered. A revised position distinguishing between the corporate and intellectual bodies of the university is offered. Three social conditions for maintaining a value-rational debate are proposed. (Author/MLW)

The Environmental Gains of Remanufacturing: Evidence from the Computer and Mobile Industry

NARCIS (Netherlands)

J. Quariguasi Frota Neto (João); J.M. Bloemhof-Ruwaard (Jacqueline)

2009-01-01

textabstractRemanufacturing has long been perceived as an environmentally-friendly initiative. The question of how remanufacturing moderates the relation between environmental impact and economic returns is still unanswered, however. In this paper, we focus our attention on the electronics industry.

Relative lack of depressive cognitions in post-myocardial infarction depression

DEFF Research Database (Denmark)

Martens, Elisabeth J; Denollet, Johan; Pedersen, Susanne S.

2006-01-01

Depression has been associated with adverse clinical events in myocardial infarction (MI) patients, but many questions about the nature of post-MI depression remain unanswered. We examined whether depressive cognitions characteristic of depression in psychiatric patients are also present in post-...

CA-MRSA puerperal mastitis and breast abscess: a potential problem emerging in Europe with many unanswered questions.

Science.gov (United States)

Pérez, Andrés; Orta, Lourdes; Padilla, Emma; Mesquida, Xavier

2013-06-01

Puerperal mastitis and breast abscess caused by community-acquired methicillin-resistant Staphylococcus aureus (CA-MRSA) is a condition rarely described in Europe to date. We report and comment on a case of CA-MRSA puerperal breast abscess in a 22-year-old primiparous mother. This aetiology was suspected before the antibiotic susceptibility profile of the strain isolated from the abscess was known on account of a history of previous skin colonisation detected in her baby. Additionally, the most striking epidemiological and therapeutic aspects, potential consequences of cross-infection between mother and child, and infection control management of this entity are briefly reviewed and discussed.

Unquestioned answers or unanswered questions: beliefs about science guide responses to uncertainty in climate change risk communication.

Science.gov (United States)

Rabinovich, Anna; Morton, Thomas A

2012-06-01

In two experimental studies we investigated the effect of beliefs about the nature and purpose of science (classical vs. Kuhnian models of science) on responses to uncertainty in scientific messages about climate change risk. The results revealed a significant interaction between both measured (Study 1) and manipulated (Study 2) beliefs about science and the level of communicated uncertainty on willingness to act in line with the message. Specifically, messages that communicated high uncertainty were more persuasive for participants who shared an understanding of science as debate than for those who believed that science is a search for absolute truth. In addition, participants who had a concept of science as debate were more motivated by higher (rather than lower) uncertainty in climate change messages. The results suggest that achieving alignment between the general public's beliefs about science and the style of the scientific messages is crucial for successful risk communication in science. Accordingly, rather than uncertainty always undermining the effectiveness of science communication, uncertainty can enhance message effects when it fits the audience's understanding of what science is. © 2012 Society for Risk Analysis.

Input Consistency in the Acquisition of Questions in Bulgarian and English: A Hypothesis Testing Model

Science.gov (United States)

Tornyova, Lidiya

2011-01-01

The goal of this dissertation is to address several major empirical and theoretical issues related to English-speaking children's difficulties with auxiliary use and inversion in questions. The empirical data on English question acquisition are inconsistent due to differences in methods and techniques used. A range of proposals about the source of…

Comparison between Two Assessment Methods; Modified Essay Questions and Multiple Choice Questions

Directory of Open Access Journals (Sweden)

Assadi S.N.* MD

2015-09-01

Full Text Available Aims Using the best assessment methods is an important factor in educational development of health students. Modified essay questions and multiple choice questions are two prevalent methods of assessing the students. The aim of this study was to compare two methods of modified essay questions and multiple choice questions in occupational health engineering and work laws courses. Materials & Methods This semi-experimental study was performed during 2013 to 2014 on occupational health students of Mashhad University of Medical Sciences. The class of occupational health and work laws course in 2013 was considered as group A and the class of 2014 as group B. Each group had 50 students.The group A students were assessed by modified essay questions method and the group B by multiple choice questions method.Data were analyzed in SPSS 16 software by paired T test and odd’s ratio. Findings The mean grade of occupational health and work laws course was 18.68±0.91 in group A (modified essay questions and was 18.78±0.86 in group B (multiple choice questions which was not significantly different (t=-0.41; p=0.684. The mean grade of chemical chapter (p<0.001 in occupational health engineering and harmful work law (p<0.001 and other (p=0.015 chapters in work laws were significantly different between two groups. Conclusion Modified essay questions and multiple choice questions methods have nearly the same student assessing value for the occupational health engineering and work laws course.

Formative student-authored question bank: perceptions, question quality and association with summative performance.

Science.gov (United States)

Walsh, Jason L; Harris, Benjamin H L; Denny, Paul; Smith, Phil

2018-02-01

There are few studies on the value of authoring questions as a study method, the quality of the questions produced by students and student perceptions of student-authored question banks. Here we evaluate PeerWise, a widely used and free online resource that allows students to author, answer and discuss multiple-choice questions. We introduced two undergraduate medical student cohorts to PeerWise (n=603). We looked at their patterns of PeerWise usage; identified associations between student engagement and summative exam performance; and used focus groups to assess student perceptions of the value of PeerWise for learning. We undertook item analysis to assess question difficulty and quality. Over two academic years, the two cohorts wrote 4671 questions, answered questions 606 658 times and posted 7735 comments. Question writing frequency correlated most strongly with summative performance (Spearman's rank: 0.24, p=<0.001). Student focus groups found that: (1) students valued curriculum specificity; and (2) students were concerned about student-authored question quality. Only two questions of the 300 'most-answered' questions analysed had an unacceptable discriminatory value (point-biserial correlation <0.2). Item analysis suggested acceptable question quality despite student concerns. Quantitative and qualitative methods indicated that PeerWise is a valuable study tool. © Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2018. All rights reserved. No commercial use is permitted unless otherwise expressly granted.

Nuclear questions

International Nuclear Information System (INIS)

Berg, Eugene

2012-01-01

Civilian and military nuclear questions fill a multitude of publications these days, especially after the Japanese tsunami and the Fukushima disaster. The author analyses some of them and highlights the links between civil and military nuclear industries, the realities of the nuclear cycle and related industrial questions before concluding on the controversial issue of weapons and their proliferation potential

Approaches to Exploring Category Information for Question Retrieval in Community Question-Answer Archives

DEFF Research Database (Denmark)

Cao, Xin; Cong, Gao; Cui, Bin

2012-01-01

, and it applies these approaches to existing question retrieval models, including a state-of-the-art question retrieval model. Experiments conducted on real CQA data demonstrate that the proposed techniques are effective and efficient and are capable of outperforming a variety of baseline methods significantly......Community Question Answering (CQA) is a popular type of service where users ask questions and where answers are obtained from other users or from historical question-answer pairs. CQA archives contain large volumes of questions organized into a hierarchy of categories. As an essential function...

Questioning ORACLE: An Assessment of ORACLE's Analysis of Teachers' Questions and [A Comment on "Questioning ORACLE"].

Science.gov (United States)

Scarth, John; And Others

1986-01-01

Analysis of teachers' questions, part of the ORACLE (Observation Research and Classroom Learning Evaluation) project research, is examined in detail. Scarth and Hammersley argue that the rules ORACLE uses for identifying different types of questions involve levels of ambiguity and inference that threaten reliability and validity of the study's…

32 questions concerning climate change (results of a questionnaire)

Energy Technology Data Exchange (ETDEWEB)

Auer, I; Boehm, R [Central Inst. for Meteorology and Geodynamics, Vienna (Austria); Steinacker, R [Vienna Univ. (Austria).Inst. for Meteorology and Geophysics

1996-12-31

The intention of the inquiry was to investigate the opinion within the scientific community about climate change questions that are believed to be already well solved in the public opinion. 32 questions were formulated that deal with 12 main assumptions about the existence, the predictability and the impacts of climate changes due to an artificially enhanced greenhouse effect. The possibilities to answer reached from `sure yes`, over `guess yes`, `not answerable or no opinion` to `guess no` and `sure no`. There were additional questions about the way the answers were gained: `by own research`, `by studying scientific literature or discussion with colleagues` and `by mass media consumption`. In the following some of the key assumptions about climate change topics will be discussed as the predictability of future evolution of climate by climate models and the detectability of an artificially enhanced greenhouse effect in climate time series. The other assumptions can be shown here only in the form of a comprehensive overview. In a very comprehensive form the results of the inquiry could be described in the following: A weak majority of climatologists believe today`s climate models to be able to describe a greenhouse gas induced climate change in global scale - much less in regional scale and not in local scale. A majority of climatologists believe an anthropogenic greenhouse gas forced climate and its impacts to be developing in the future but not already at present. The shape of the opinion spectra is in most cases far from that of a scientifically solved problem - a lot of work still has to be done

32 questions concerning climate change (results of a questionnaire)

Energy Technology Data Exchange (ETDEWEB)

Auer, I.; Boehm, R. [Central Inst. for Meteorology and Geodynamics, Vienna (Austria); Steinacker, R. [Vienna Univ. (Austria).Inst. for Meteorology and Geophysics

1995-12-31

The intention of the inquiry was to investigate the opinion within the scientific community about climate change questions that are believed to be already well solved in the public opinion. 32 questions were formulated that deal with 12 main assumptions about the existence, the predictability and the impacts of climate changes due to an artificially enhanced greenhouse effect. The possibilities to answer reached from `sure yes`, over `guess yes`, `not answerable or no opinion` to `guess no` and `sure no`. There were additional questions about the way the answers were gained: `by own research`, `by studying scientific literature or discussion with colleagues` and `by mass media consumption`. In the following some of the key assumptions about climate change topics will be discussed as the predictability of future evolution of climate by climate models and the detectability of an artificially enhanced greenhouse effect in climate time series. The other assumptions can be shown here only in the form of a comprehensive overview. In a very comprehensive form the results of the inquiry could be described in the following: A weak majority of climatologists believe today`s climate models to be able to describe a greenhouse gas induced climate change in global scale - much less in regional scale and not in local scale. A majority of climatologists believe an anthropogenic greenhouse gas forced climate and its impacts to be developing in the future but not already at present. The shape of the opinion spectra is in most cases far from that of a scientifically solved problem - a lot of work still has to be done

Curiosity Questions

Science.gov (United States)

Nelsen, Jane; DeLorenzo, Chip

2010-01-01

Have you ever found yourself lecturing a child, with the best of intentions, in an attempt to help him or her learn a lesson or process a situation in a manner that you feel will be productive? Curiosity questions, which the authors also call What and How questions, help children process an experience, event, or natural consequence so that they…

An urban geography of globalisation : New urban structures in the age of hyper-connectivity

NARCIS (Netherlands)

Rocco, R.

2008-01-01

How is Globalisation changing the form and spatial structure of cities today? Deceptively simple, this question presents us with a number of methodological challenges and unanswered theoretical problems. What is globalization? Can we define a series of distinctive new phenomena constituting a

Secure oil and alternative energy: the geopolitics of energy paths of China and the European Union

NARCIS (Netherlands)

Amineh, M.P.; Guang, Y.

2012-01-01

While intensive cooperation between China and the EU in the fields of energy use, environmental protection and sustainability is highly needed the question remains unanswered how this cooperation could be organized. This volume puts the geopolitical implementation of China's and the EU's energy

Observations of exotic inner core waves

NARCIS (Netherlands)

Waszek, Lauren; Deuss, A.F.|info:eu-repo/dai/nl/412396610

2015-01-01

The seismic structure of Earth’s inner core is highly complex, displaying strong anisotropy and further regional variations. However, few seismic waves are sensitive to the inner core and fundamental questions regarding the origin of the observed seismic features remain unanswered. Thus, new

Epidemiology and management of depression in cancer patients

NARCIS (Netherlands)

Ng, C.G.

2012-01-01

Depression is the most frequent psychiatric comorbidity in cancer patients especially those in terminal stage. Despite the large amount of studies on depression in cancer patients, there are a lot of unanswered questions with respect to diagnosis, prevalence and treatment. Diagnosing depression in

Awake Craniotomy and Coaching

NARCIS (Netherlands)

Ruis, Carla; Huenges Wajer, Irene; Robe, Pierre; van Zandvoort, Martine

2014-01-01

Background: The importance of monitoring cognition during awake craniotomy has been well described in previous studies. The relevance of being coached during such a procedure has received less attention and questions still remain unanswered about what factors are the most important herein.

The prevalence of lower urinary tract symptoms in men and women in four centres. The UrEpik study.

NARCIS (Netherlands)

Boyle, P.; Robertson, C.; Mazzetta, C.; Keech, M.; Hobbs, F.D.; Fourcade, R.; Kiemeney, L.A.L.M.; Lee, C.

2003-01-01

OBJECTIVE: To evaluate the epidemiology of lower urinary tract symptoms (LUTS) among men and women, as there are significant unanswered questions about the prevalence and impact of LUTS in different populations. SUBJECTS AND METHODS: A population-based, cross-sectional survey was completed in

Is it possible to catch leukemia from a cat?

NARCIS (Netherlands)

Horzinek, M.C.; Nowotny, N.; Uthman, A.; Haas, O.A.; Borkhardt, A.; Lechner, K.; Egberink, H.F.; Mostl, K.

1995-01-01

The commentary of Donaldson and colleagues lists several of the unanswered questions concerning the potential oncogenicity of feline leukaemia virus (FeLV) and feline immunodeficiency virus (FIV) in human beings. As a contribution to this debate, we report a study in patients with

Reminiscence bump in memory for public events

NARCIS (Netherlands)

Janssen, S.M.J.; Murre, J.M.J.; Meeter, M.

2008-01-01

People tend to recall more personal events from adolescence and early adulthood than from other lifetime periods. Most evidence suggests that differential encoding causes this reminiscence bump. However, the question why personal events are encoded better in those periods is still unanswered. To

Deepening Representative Democracy through Fiscal ...

African Journals Online (AJOL)

The ideas behind composite budgeting for effective fiscal decentralisation are noble, but the implementation is constrained by organisational, coordination, structural and technical factors. The key unanswered question is whether the failure to deliver the goods of fiscal decentralisation is fettered by misnomer ...

Dyscalculia: Neuroscience and Education

Science.gov (United States)

Kaufmann, Liane

2008-01-01

Background: Developmental dyscalculia is a heterogeneous disorder with largely dissociable performance profiles. Though our current understanding of the neurofunctional foundations of (adult) numerical cognition has increased considerably during the past two decades, there are still many unanswered questions regarding the developmental pathways of…

Future trials of endovascular mechanical recanalisation therapy in acute ischemic stroke patients: a position paper endorsed by ESMINT and ESNR. Pt. 1. Current situation and major research questions

Energy Technology Data Exchange (ETDEWEB)

Fiehler, Jens [University Medical Centre Hamburg-Eppendorf, Department of Neuroradiology, Hamburg (Germany); Soederman, Michael [Karolinska University Hospital, Department of Neuroradiology, Stockholm (Sweden); Turjman, Francis [Hopital Neurologique, Centre de Neurosciences Cognitives, Department of Neuroradiology, Lyon (France); White, Philip M. [Western General Hospital, University of Edinburgh, Department of Clinical Neurosciences, Edinburgh (United Kingdom); Bakke, Soeren Jacob [Oslo University Hospital, Rikshospitalet, Department of Neuroradiology, Oslo (Norway); Mangiafico, Salvatore [University Hospital Careggi, Interventional Neuroradiology Unit, Florence (Italy); Kummer, Ruediger von [University of Dresden, Department of Neuroradiology, Dresden (Germany); Muto, Mario [University of Naples, Department of Neuroradiology, Naples (Italy); Cognard, Christophe [Hopital Purpan, Service de Neuroradiologie, Toulouse (France); Gralla, Jan [Inselspital Bern, Department of Neuroradiology, Bern (Switzerland)

2012-12-15

A new era of stroke treatment may have begun with mechanical thrombectomy (MT) by fully deployed closed-cell self-expanding stents (stent-triever). Multiple case series and the first randomised controlled trials (RCTs) have now been published. More studies are under way involving large numbers of patients, which in turn has resulted in less strict ''pragmatic'' study protocols. Problems with current trials include a lack of standardisation in the conduct of the recanalisation procedure, the definition of primary endpoints such as the grade of arterial recanalisation and tissue reperfusion, and the post-surgical care provided. In Part 1 of this two part series, we outline the current situation and the major research questions. (orig.)

Experimental approaches to predict allergenic potential of novel food

DEFF Research Database (Denmark)

Madsen, Charlotte Bernhard; Kroghsbo, Stine; Bøgh, Katrine Lindholm

2013-01-01

’t know under what circumstances oral tolerance develops. With all these unanswered questions, it is a big challenge to designan animal model that, with relatively few animals, is able to predict if a food protein is a potential allergen. An even larger challenge is to predict its potency, a prerequisite...... for risk evaluation.Attempts have been made to rank proteins according to their allergenic potency based on the magnitude of the IgE response in experimental animals. This ranking has not included abundance as a parameter. We may be able to predict potential allergenicity i.e. hazard but our lack......There are many unanswered questions relating to food allergy sensitization in humans. We don’t know under what circumstances sensitization takes place i.e. route (oral, dermal, respiratory), age, dose, frequencyof exposure, infection or by-stander effect of other allergens. In addition we don...

THE EXPLICIT COMPREHENSION-STRATEGY INSTRUCTION: QUESTION-ANSWER RELATIONSHIP VS SELF-QUESTIONING

Directory of Open Access Journals (Sweden)

Lalu Thohir

2017-12-01

Full Text Available This study was aimed at examining and comparing the effectiveness of the Question-Answer Relationship (QAR and Self-Questioning (SQ strategies in improving the reading ability of the undergraduate students. This study was a quasi-experimental study in which two out of three classes of the third semester students at English department of Mataram University were selected randomly to receive either QAR strategy or SQ strategy instructions for ten weekly meetings. The findings of pre- and posttest with multiple-choice questions revealed that both comprehension strategies were effective in improving the undergraduate students‘ reading ability. The findings from the posttest with multiple-choice questions indicated the students who received SQ strategy instruction scored significantly higher than those students who received QAR strategy instruction. On the other hand, the students who received QAR strategy instruction scored slightly higher than those students who received SQ strategy instruction in the posttest with open-ended questions.

No major differences found between the effects of microwave-based and conventional heat treatment methods on two different liquid foods.

Science.gov (United States)

Géczi, Gábor; Horváth, Márk; Kaszab, Tímea; Alemany, Gonzalo Garnacho

2013-01-01

Extension of shelf life and preservation of products are both very important for the food industry. However, just as with other processes, speed and higher manufacturing performance are also beneficial. Although microwave heating is utilized in a number of industrial processes, there are many unanswered questions about its effects on foods. Here we analyze whether the effects of microwave heating with continuous flow are equivalent to those of traditional heat transfer methods. In our study, the effects of heating of liquid foods by conventional and continuous flow microwave heating were studied. Among other properties, we compared the stability of the liquid foods between the two heat treatments. Our goal was to determine whether the continuous flow microwave heating and the conventional heating methods have the same effects on the liquid foods, and, therefore, whether microwave heat treatment can effectively replace conventional heat treatments. We have compared the colour, separation phenomena of the samples treated by different methods. For milk, we also monitored the total viable cell count, for orange juice, vitamin C contents in addition to the taste of the product by sensory analysis. The majority of the results indicate that the circulating coil microwave method used here is equivalent to the conventional heating method based on thermal conduction and convection. However, some results in the analysis of the milk samples show clear differences between heat transfer methods. According to our results, the colour parameters (lightness, red-green and blue-yellow values) of the microwave treated samples differed not only from the untreated control, but also from the traditional heat treated samples. The differences are visually undetectable, however, they become evident through analytical measurement with spectrophotometer. This finding suggests that besides thermal effects, microwave-based food treatment can alter product properties in other ways as well.

No major differences found between the effects of microwave-based and conventional heat treatment methods on two different liquid foods.

Directory of Open Access Journals (Sweden)

Gábor Géczi

Full Text Available Extension of shelf life and preservation of products are both very important for the food industry. However, just as with other processes, speed and higher manufacturing performance are also beneficial. Although microwave heating is utilized in a number of industrial processes, there are many unanswered questions about its effects on foods. Here we analyze whether the effects of microwave heating with continuous flow are equivalent to those of traditional heat transfer methods. In our study, the effects of heating of liquid foods by conventional and continuous flow microwave heating were studied. Among other properties, we compared the stability of the liquid foods between the two heat treatments. Our goal was to determine whether the continuous flow microwave heating and the conventional heating methods have the same effects on the liquid foods, and, therefore, whether microwave heat treatment can effectively replace conventional heat treatments. We have compared the colour, separation phenomena of the samples treated by different methods. For milk, we also monitored the total viable cell count, for orange juice, vitamin C contents in addition to the taste of the product by sensory analysis. The majority of the results indicate that the circulating coil microwave method used here is equivalent to the conventional heating method based on thermal conduction and convection. However, some results in the analysis of the milk samples show clear differences between heat transfer methods. According to our results, the colour parameters (lightness, red-green and blue-yellow values of the microwave treated samples differed not only from the untreated control, but also from the traditional heat treated samples. The differences are visually undetectable, however, they become evident through analytical measurement with spectrophotometer. This finding suggests that besides thermal effects, microwave-based food treatment can alter product properties in other

Student questions in urban middle school science communities of practice

Science.gov (United States)

Groome, Meghan

This dissertation examines student questions within three Communities of Practice (CoP), all urban middle school science environments. The study analyzed student questions from a sociocultural perspective and used ethnographic research techniques to detail how the CoP's shaped questions in the classroom. In the first study, two case study girls attempted to navigate questioning events that required them to negotiation participation. Their access to participation was blocked by participation frameworks that elevated some students as "gatekeepers" while suppressing the participation of others. The next two studies detail the introduction of written questioning opportunities, one into a public middle school classroom and the other into an informal classroom. In both studies, students responded to the interventions differently, most notable the adoption of the opportunity by female students who do not participate orally. Dissertation-wide findings indicate all students were able to ask questions, but varied in level of cognitive complexity, and the diagnostic interventions were able to identify students who were not known to be "target students", students who asked a high number of questions and were considered "interested in science". Some students' roles were as "gatekeepers" to participation of their peers. Two out of three teachers in the studies reported major shifts in their teaching practice due to the focus on questions and the methods used here have been found to be effective in producing educational research as well as supporting high-need classrooms in prior research. In conclusion, these studies indicate that social factors, including participation frameworks, gender dynamics, and the availability of alternative participation methods, play an important role in how students ask science-related questions. It is recommended that researchers continue to examine social factors that reduce student questions and modify their teaching strategies to facilitate

Parenting Practices in Cultural Context: An Ecological Perspective

Science.gov (United States)

Zarnegar, Zohreh

2015-01-01

Despite general consensus that parenting practices influence the developmental processes of children, many questions about the impacts of parenting practices on child development within the cultural context remain unanswered. This article presents how cultural templates influence parenting practices and developmental processes of young children.…

From galaxy to universe? A cross-disciplinary review and analysis of public values publications from 1969 to 2012

NARCIS (Netherlands)

van der Wal, Z.; Nabatchi, T.; de Graaf, G.

2015-01-01

The study of public values (PVs) is generating growing interest in public administration and public management, yet many challenges and unanswered questions remain. For the study of PVs to progress, we need to go beyond the traditional boundaries of public administration and management, to explore

Stability and Change of Behavioral and Emotional Screening Scores

Science.gov (United States)

Dever, Bridget V.; Dowdy, Erin; Raines, Tara C.; Carnazzo, Katherine

2015-01-01

Universal screening for behavioral and emotional difficulties is integral to the identification of students needing early intervention and prevention efforts. However, unanswered questions regarding the stability of screening scores impede the ability to determine optimal strategies for subsequent screening. This study examined the 2-year…

Travel-Related Venous Thrombosis: Results from a Large Population-Based Case Control Study (MEGA Study)

NARCIS (Netherlands)

Cannegieter, Suzanne C.; Doggen, Catharina Jacoba Maria; van Houwelingen, Hans C.; Rosendaal, Frits R.

2006-01-01

Background Recent studies have indicated an increased risk of venous thrombosis after air travel. Nevertheless, questions on the magnitude of risk, the underlying mechanism, and modifying factors remain unanswered. Methods and Findings We studied the effect of various modes and duration of travel on

Introduction: The Future of Social Movement Research

NARCIS (Netherlands)

Stekelenburg, Jacquelien Van; Roggeband, Conny; Stekelenburg, Jacquelien Van; Roggeband, Conny; Klandermans, Bert

2013-01-01

In The Future of Social Movement Research, some of the most influential scholars in the field provide a wide-ranging understanding of how social movements arise and persist, engendering unanswered questions pointing to new theoretical strands and fields of research. The resulting work is

From entrepreneurship to economic growth: a three stage approach

NARCIS (Netherlands)

van Hemert, P.P.

2008-01-01

Over time, different economic theories have supported the idea that entrepreneurship and innovation are essential for spurring economic growth. One question, however, remains unanswered, namely, why some regions in different parts of the world manage to enter into a cycle of growth and development

From entrepreneurship to economic growth, a three stage approach

NARCIS (Netherlands)

van Hemert, P.P.

2007-01-01

Over time, different economic theories have supported the idea that entrepreneurship and innovation are essential for spurring economic growth. One question, however, remains unanswered, namely, why some regions in different parts of the world manage to enter into a cycle of growth and development

Editorial

African Journals Online (AJOL)

Raoul

2009-09-04

Sep 4, 2009 ... Provider Initiated Testing and Counseling (PITC) for HIV in resource-limited clinical settings: important questions unanswered. Joseph Becker 1&, Landry Tsague2, Ruben Sahabo2, Peter Twyman2. 1Stanford University School of Medicine, Department of Medicine, Division of Emergency Medicine, ...

Institutional aspects of integrating irrigation into urban wastewater management: the case of Hanoi, Vietnam

NARCIS (Netherlands)

Evers, J.G.; Huibers, F.P.; Vliet, van B.J.M.

2010-01-01

Wastewater flows of metropolitan cities and their downstream use for irrigation are often associated with technical systems. However, an engineering approach on its own will leave questions unanswered at the socio-technical and institutional level. Research was carried out in Hanoi, Vietnam, on the

Institutional aspects of integrating irrigation into urban wastewater management: the case of Hanoi, Vietnam

NARCIS (Netherlands)

Evers, J.G.; Huibers, Frans P.; van Vliet, Bas J.M.

2008-01-01

Wastewater flows of metropolitan cities and their downstream use for irrigation are often associated with technical systems. However, an engineering approach on its own will leave questions unanswered at the socio-technical and institutional level. Research was carried out in Hanoi, Vietnam, on the

The City as Metaphor for Integrated Learning in the Arts.

Science.gov (United States)

Efland, Arthur

2000-01-01

Discusses a cognitive model that is an alternative to Jerome Bruner's spiral curriculum, developed and based on the metaphor that the mind's knowledge base is a lattice. States that the lattice metaphor offers an understanding of cognition but some questions still remained unanswered. (CMK)

A Critical Review of Models of Perinatal Infection

NARCIS (Netherlands)

Dean, Justin M.; Shi, Zhongjie; Fleiss, Bobbi; Gunn, Katherine C.; Groenendaal, Floris; Van Bel, Frank; Derrick, Matthew; Juul, Sandra E.; Tan, Sidhartha; Gressens, Pierre; Mallard, Carina; Bennet, Laura; Gunn, Alistair J.

2015-01-01

One of the central, unanswered questions in perinatology is why preterm infants continue to have such poor long-term neurodevelopmental, cognitive and learning outcomes, even though severe brain injury is now rare. There is now strong clinical evidence that one factor underlying disability may be

Asking Questions in Academia

DEFF Research Database (Denmark)

Hansen, Annette Skovsted

2014-01-01

Motivation for the activity In academia the most important skill is to ask academically relevant and sound questions. This is not easy and students need to practice asking questions orally and in writing before they write research papers.......Motivation for the activity In academia the most important skill is to ask academically relevant and sound questions. This is not easy and students need to practice asking questions orally and in writing before they write research papers....

EVIDENCE ON THE CHARACTERISTICS OF WOMEN ENTREPRENEURS IN BRAZIL: AN EMPIRICAL ANALYSIS

OpenAIRE

Andrea E. Smith-Hunter; Joshua Leone

2010-01-01

Interest in women entrepreneurs from various backgrounds and perspectives have led to increased publication in the literature about women entrepreneur issues. However many questions remain unanswered. This article aims to answer some of these questions by providing another perspective on women entrepreneurs. Specifically this study examines women entrepreneurs from Brasil, using a sample across racial lines. The article examines the characteristics of women entrepreneurs across three key cate...

Didžiojo penketo asmenybės bruožų ir kognityvinio stiliaus sąsajos

OpenAIRE

Bukšnytė, Loreta; Kovalčikienė, Kristina; Ciūnytė, Aldona

2012-01-01

In the realm of empirical research, it is known that personality traits and cognitive style are related. However, still remain unanswered questions (for example, the results are contradictory about the relationship between neuroticism and cognitive style; also, there is no answer to the question of whether agreeableness is related to cognitive style). Furthermore, although the empirical studies of relationships between personality traits and cognitive style were carried out in various countri...

Improving Student Question Classification

Science.gov (United States)

Heiner, Cecily; Zachary, Joseph L.

2009-01-01

Students in introductory programming classes often articulate their questions and information needs incompletely. Consequently, the automatic classification of student questions to provide automated tutorial responses is a challenging problem. This paper analyzes 411 questions from an introductory Java programming course by reducing the natural…

The therapeutic alliance in internet interventions: A narrative review and suggestions for future research.

Science.gov (United States)

Berger, Thomas

2017-09-01

Research on Internet interventions has grown rapidly over the recent years and evidence is growing that Internet-based treatments often result in similar outcomes as conventional face-to-face psychotherapy. Yet there are still unanswered concerns such as whether a therapeutic alliance can be established over the Internet and whether the alliance is important in this new treatment format. A narrative review of studies formally assessing the therapeutic alliance in Internet interventions was conducted. It is the first review summarizing findings on the therapeutic alliance that (i) distinguishes between different forms of Internet interventions and (ii) does not restrict itself to specific Internet-based treatment formats such as guided self-help treatments, e-mail or videoconferencing therapies. Independent of communication modalities, diagnostic groups and amount of contact between clients and therapists, client-rated alliance scores were high, roughly equivalent to alliance ratings found in studies on face-to-face therapy. Mixed results were found regarding the therapist-rated alliance and alliance-outcome associations. The review points to the limitations of the available evidence and identifies unanswered questions. It is concluded that one of the major tasks for future research is to identify unique characteristics of the therapeutic alliance in the different treatment formats.

Guided Discovery with Socratic Questioning

Directory of Open Access Journals (Sweden)

M. Hakan Türkçapar

2015-04-01

Full Text Available “The Socratic method” is a way of teaching philosophical thinking and knowledge by asking questions. It was first used by in ancient times by the Greek philosopher Socrates who taught his followers by asking questions; these conversations between them are known as “Socratic dialogues”. In this methodology, no new knowledge is taught to the individual; rather, the individual is guided to remember and rediscover what was formerly known through this process. The main method used in cognitive therapy is guided discovery. There are various methods of guided discovery in cognitive therapy. The form of verbal exchange between the therapist and client which is used during the process of cognitive behavioral therapy is known as “socratic questioning”. In this method the goal is to make the client rediscover, with a series of questions, a piece of knowledge which he could otherwise know but is not presently conscious of. The Socratic Questioning consists of several steps, including: identifying the problem by listening to the client and making reflections, finding alternatives by examining and evaluating, reidentification by using the newly rediscovered information and questioning the old distorted belief, and reaching a new conclusion and applying it. Question types used during these procedures are: questions for collecting information, questions revealing meanings, questions revealing beliefs, questions about behaviours during similar past experiences, analytic questions and analytic synthesis questions. In order to make the patient feel understood, it is important to be empathetic and summarize the problem during the interview. In this text, steps of Socratic Questioning-Guided Discovery will be reviewed with sample dialogues provided for each step. [JCBPR 2015; 4(1.000: 47-53

Humanistic Approaches to the Understanding and Treatment of Anorexia Nervosa.

Science.gov (United States)

Dittmar, Helga; Bates, Brian

1987-01-01

Summarizes some attempts to understand the causes and consequent treatments of anorexia nervosa from the viewpoints of psychoanalytically informed, family, existential and feminist psychology. These perspectives, which focus on the individual experience of the anorexic, leave many questions unanswered, but provide fresh frameworks from which to…

'In situ simulation' versus 'off site simulation' in obstetric emergencies and their effect on knowledge, safety attitudes, team performance, stress, and motivation

DEFF Research Database (Denmark)

Sørensen, Jette Led; Van der Vleuten, Cees; Lindschou, Jane

2013-01-01

learner outcomes. However, many questions on how SBME can be optimized remain unanswered. One unresolved issue is how 'in situ simulation' (ISS) versus 'off site simulation' (OSS) impact learning. ISS means simulation-based training in the actual patient care unit (in other words, the labor room...

Effects of large herbivores on wood pasture dynamics in a European wetland system

NARCIS (Netherlands)

Cornelissen, P.; Bokdam, J.; Sykora, K.V.; Berendse, F.

2014-01-01

Whether self-regulating large herbivores play a key role in the development of wood-pasture landscapes remains a crucial unanswered question for both ecological theory and nature conservation. We describe and analyse how a ‘partly self-regulating’ population of cattle, horses and red deer affected

The impact of different policy environments on agricultural land use in Europe

NARCIS (Netherlands)

Meijl, van H.; Rheenen, van T.; Tabeau, A.A.; Eickhout, B.

2006-01-01

The impact of globalization on trade, production and land use was key to the Doha development round. Although many studies have shown the positive influence of liberalization on trade and production, the environmental questions remain unanswered in most studies. Here we present a combination of an

Pramana – Journal of Physics | Indian Academy of Sciences

Indian Academy of Sciences (India)

Based on some of our recent observations on phase separation of a multicomponent alloy involving hydration of cementitious material, it is proposed to discuss some unanswered questions pertinent to the validity of dynamical scaling laws addressing some issues like (i) uniqueness of characteristic length (), (ii) the ...

Pharmacokinetics of Melatonin

DEFF Research Database (Denmark)

Andersen, Lars Peter Holst; Gögenur, Ismail; Rosenberg, Jacob

2016-01-01

Despite widespread clinical application of melatonin, several unanswered questions remain regarding the pharmacokinetics of this drug. This lack of knowledge may contribute to the inconsistency of results in previous clinical studies. Currently, a t max value of 30-45 min and a t ½elimination of ...

Intelligent Dispositions: Dewey, Habits and Inquiry in Teacher Education

Science.gov (United States)

Nelsen, Peter J.

2015-01-01

Despite much debate in the literature, accrediting agencies continue to require that teacher education programs demonstrate that candidates possess requisite sets of dispositions deemed necessary for licensure. At least three unresolved and important questions remain unanswered that directly affect programs' abilities to do so: Are…

Representation without Taxation: Citizenship and Suffrage in Indian Country.

Science.gov (United States)

Phelps, Glenn A.

1985-01-01

Reviews history of Arizona Indian voting rights. Details current dispute over voting rights in Apache County (Arizona). Explores three unanswered questions in light of current constitutional interpretation. Stresses solution to political disputes will require climate of mutual trust, awareness of constitutional rights/obligations of all concerned,…

Boiling Blood : Chemistry of Vital Fluids 
in Dutch Enlightenment Culture

NARCIS (Netherlands)

Verwaal, Ruben

2015-01-01

What is blood? Despite William Harvey’s discovery of the circulation of blood, many questions about blood itself unanswered. This paper asks how and why Dutch medical men in the eighteenth century initiated studies to understand the properties of blood. Some professor such as Herman Boerhaave and

Continuous gradient temperature Raman spectroscopy of the long chain polyunsaturated fatty acids Docosapentaenoic (DPA, 22:5n-6) and Docosahexaenoic (DHA; 22:6n-3) from -100 to 20° C

Science.gov (United States)

The structural, cognitive and visual development of the human brain and retina strictly require long-chain polyunsaturated fatty acids (LC-PUFA). Excluding water, the mammalian brain is about 60% lipid. One of the great unanswered questions with respect to biological science in general is the absolu...

Gryffindor, Hufflepuff, Ravenclaw or Slytherin: Your Context influences Your Future

DEFF Research Database (Denmark)

Lindahl Thomassen, Mette; Williams Middleton, Karen; Breum Ramsgaard, Michael

, little has been transferred into research of how educators and educational designers can actively work with their context. Implications With this study, we are introducing context as a design parameter for entrepreneurship educators. Nonetheless, there are still a number of unanswered questions...... environment for their students....

Think Tanks in Europe

DEFF Research Database (Denmark)

Kelstrup, Jesper Dahl

in their national contexts. Questions regarding patterns and differences in think tank organisations and functions across countries have largely been left unanswered. This paper advances a definition and research design that uses different expert roles to categorise think tanks. A sample of 34 think tanks from...

Gender Issues in Technical Communication Studies: An Overview of the Implications for the Profession, Research, and Pedagogy.

Science.gov (United States)

Allen, Jo

1991-01-01

Presents an overview of research and unanswered questions related to gender issues in technical communication. Addresses the consequences of the feminization of technical communication, research on gender differences in technical communication, and the means for encouraging a more gender-balanced view of business and industry. (SR)

Rooting the biggest problems in physics

DEFF Research Database (Denmark)

Javadi, Hossein; Forouzbakhsh, Farshid

2016-01-01

to combine these three theories of classical mechanics, quantum mechanics and relativity in order to reach to a unique physics. Eventually, by answering the unanswered questions, the physics problems will be solved. In this paper, the stems of physics problems are expressed and the solution of them...

Changing Roots : Remodelling after the Ross Operation

NARCIS (Netherlands)

A. Mookhoek (Aart)

2016-01-01

textabstractThe Ross operation is a surgical intervention in which a diseased aortic valve is replaced by the pulmonary valve of the same patient. A donor valve replaces the pulmonary valve. In this thesis, several key unanswered clinical questions are explored. Early mortality after the Ross

Antiangiogenic therapy for breast cancer

DEFF Research Database (Denmark)

Nielsen, D.L.; Andersson, M.; Andersen, Jon Alexander Lykkegaard

2010-01-01

tyrosine kinase activity, such as sorafenib, appear promising. While, the role of sunitinib and inhibitors of mammalian target of rapamycin (mTOR) in breast cancer has to be defined. Several unanswered questions remain, such as choice of drug(s), optimal duration of therapy and patient selection criteria...

Puzzles in quantum gravity : what can black hole microstates teach us about quantum gravity?

NARCIS (Netherlands)

El-Showk, S.

2009-01-01

In this thesis we review two independent lines of research directed towards helping us construct a theory of Quantum Gravity. While, in string/M-theory, we already enjoy a potential theory of this type there remain many unanswered foundational questions and missing precepts. By probing the

Epistemology: 5 Questions

DEFF Research Database (Denmark)

Epistemology: 5 Questions is a collection of short interviews based on 5 questions presented to some of the most influential and prominent scholars in epistemology. We hear their views on epistemology with particular emphasis on the intersection between mainstream and formal approaches to the field...

INDUSTRIAL BRANDING – DOES IT PAY OFF?

Directory of Open Access Journals (Sweden)

Anca BUTNARIU

2017-12-01

Full Text Available In a world characterized by the growth of global competition, a key question raised by business-to-business marketers is if brands in industrial markets really pay off, that is in which contexts and for what type of customers branding efforts are important and can bring competitive advantages for the companies owning those brands. The particularities and importance of branding in business has become a major field of scientific debate in the last years, but there are still questions unanswered and aspects unclear and under researched. Traditionally, B2B managers have been more skeptical about the benefits of branding, arguing that the organizational buying process is rational and focused on functional characteristics of the products and not based on the emotional values used in the B2C context. In this paper, we review the literature on brand equity in industrial markets and propose a synthetic conceptual model, with the purpose to shed more light on the issue of industrial branding.

What is the current status of ovarian suppression/ablation in women with premenopausal early-stage breast cancer?

Science.gov (United States)

Higgins, Michaela J; Davidson, Nancy E

2009-01-01

The role of ovarian suppression/ablation (OS/OA) in premenopausal women with hormone receptor-positive breast cancer has been evolving for more than a century. It is clear that OS/OA is an effective adjuvant therapy for these women, but despite numerous studies enrolling thousands of women, many unanswered questions remain. In particular, a major question is whether additional benefit is gained with combination treatment comprising luteinizing hormone-releasing hormone (LH-RH) agonists and tamoxifen over tamoxifen alone. Ongoing trials also are assessing the coupling of aromatase inhibitors (traditionally contraindicated in these patients because of paradoxic stimulation of estrogen production) and LH-RH agonists. Any potential disease-free or overall survival advantage of combination treatment must be balanced against a possible increase in adverse effects and impairment of quality of life. This review focuses on new data on how to incorporate OS/OA into the rational treatment of this challenging patient population.

Manganese oxide-based materials as electrochemical supercapacitor electrodes.

Science.gov (United States)

Wei, Weifeng; Cui, Xinwei; Chen, Weixing; Ivey, Douglas G

2011-03-01

Electrochemical supercapacitors (ECs), characteristic of high power and reasonably high energy densities, have become a versatile solution to various emerging energy applications. This critical review describes some materials science aspects on manganese oxide-based materials for these applications, primarily including the strategic design and fabrication of these electrode materials. Nanostructurization, chemical modification and incorporation with high surface area, conductive nanoarchitectures are the three major strategies in the development of high-performance manganese oxide-based electrodes for EC applications. Numerous works reviewed herein have shown enhanced electrochemical performance in the manganese oxide-based electrode materials. However, many fundamental questions remain unanswered, particularly with respect to characterization and understanding of electron transfer and atomic transport of the electrochemical interface processes within the manganese oxide-based electrodes. In order to fully exploit the potential of manganese oxide-based electrode materials, an unambiguous appreciation of these basic questions and optimization of synthesis parameters and material properties are critical for the further development of EC devices (233 references).

The Priority of the Question: Focus Questions for Sustained Reasoning in Science

Science.gov (United States)

Lustick, David

2010-08-01

Science education standards place a high priority on promoting the skills and dispositions associated with inquiry at all levels of learning. Yet, the questions teachers employ to foster sustained reasoning are most likely borrowed from a textbook, lab manual, or worksheet. Such generic questions generated for a mass audience, lack authenticity and contextual cues that allow learners to immediately appreciate a question’s relevance. Teacher queries intended to motivate, guide, and foster learning through inquiry are known as focus questions. This theoretical article draws upon science education research to present a typology and conceptual framework intended to support science teacher educators as they identify, develop, and evaluate focus questions with their students.

Barriers to optimal care between physicians and lesbian, gay, bisexual, transgender, and questioning adolescent patients.

Science.gov (United States)

Kitts, Robert Li

2010-01-01

The objective of this article was to identify barriers to optimal care between physicians and LGBTQ (lesbian, gay, bisexual, transgender, and questioning) adolescents. To this end, 464 anonymous, self-administered surveys were distributed in 2003 to residents and attending physicians in pediatrics, internal medicine, obstetrics-gynecology, psychiatry, emergency medicine, and family practice at Upstate Medical University. The survey included questions pertaining to practice, knowledge, and attitude pertaining to lesbian, gay, transgender, or questioning (LGBTQ) adolescents. One hundred eight four surveys were returned. The majority of physicians would not regularly discuss sexual orientation, sexual attraction, or gender identity while taking a sexual history from a sexually active adolescent. As well, the majority of physicians would not ask patients about sexual orientation if an adolescent presented with depression, suicidal thoughts, or had attempted suicide. If an adolescent stated that he or she was not sexually active, 41% of physicians reported that they would not ask additional sexual health-related questions. Only 57% agreed to an association between being a LGBTQ adolescent and suicide. The majority of physicians did not believe that they had all the skills they needed to address issues of sexual orientation with adolescents, and that sexual orientation should be addressed more often with these patients and in the course of training. This study concludes that barriers in providing optimal care for LGBTQ adolescents can be found with regard to practice, knowledge, and attitude regardless of medical field and other demographics collected. Opportunities exist to enhance care for LGBTQ adolescents.

A National Survey of Music Education Majors' Confidence in Teaching Improvisation

Science.gov (United States)

Bernhard, H. Christian, II.; Stringham, David A.

2016-01-01

The purpose of the study was to investigate undergraduate music education majors' confidence in teaching improvisation, according to the NAfME (1994) K-12 Achievement Standards. Specific research questions were: 1) How confident are music education majors in implementing the 11 improvisation achievement standards for grades K-12? 2) How confident…

Characteristics and contents of dreams.

Science.gov (United States)

Schredl, Michael

2010-01-01

Dreams have been studied from different perspectives: psychoanalysis, academic psychology, and neurosciences. After presenting the definition of dreaming and the methodological tools of dream research, the major findings regarding the phenomenology of dreaming and the factors influencing dream content are briefly reviewed. The so-called continuity hypothesis stating that dreams reflect waking-life experiences is supported by studies investigating the dreams of psychiatric patients and patients with sleep disorders, i.e., their daytime symptoms and problems are reflected in their dreams. Dreams also have an effect on subsequent waking life, e.g., on daytime mood and creativity. The question about the functions of dreaming is still unanswered and open to future research. Copyright © 2010 Elsevier Inc. All rights reserved.

Communities under climate change

DEFF Research Database (Denmark)

Nogues, David Bravo; Rahbek, Carsten

2011-01-01

The distribution of species on Earth and the interactions among them are tightly linked to historical and contemporary climate, so that global climate change will transform the world in which we live. Biological models can now credibly link recent decadal trends in field data to climate change......, but predicting future impacts on biological communities is a major challenge. Attempts to move beyond general macroecological predictions of climate change impact on one hand, and observations from specific, local-scale cases, small-scale experiments, or studies of a few species on the other, raise a plethora...... of unanswered questions. On page 1124 of this issue, Harley (1) reports results that cast new light on how biodiversity, across different trophic levels, responds to climate change....

Infrastructure Support for Collaborative Pervasive Computing Systems

DEFF Research Database (Denmark)

Vestergaard Mogensen, Martin

Collaborative Pervasive Computing Systems (CPCS) are currently being deployed to support areas such as clinical work, emergency situations, education, ad-hoc meetings, and other areas involving information sharing and collaboration.These systems allow the users to work together synchronously......, but from different places, by sharing information and coordinating activities. Several researchers have shown the value of such distributed collaborative systems. However, building these systems is by no means a trivial task and introduces a lot of yet unanswered questions. The aforementioned areas......, are all characterized by unstable, volatile environments, either due to the underlying components changing or the nomadic work habits of users. A major challenge, for the creators of collaborative pervasive computing systems, is the construction of infrastructures supporting the system. The complexity...

Attitudes towards assisted dying are influenced by question wording and order: a survey experiment.

Science.gov (United States)

Magelssen, Morten; Supphellen, Magne; Nortvedt, Per; Materstvedt, Lars Johan

2016-04-27

Surveys on attitudes towards assisted dying play an important role in informing public debate, policy and legislation. Unfortunately, surveys are often designed with insufficient attention to framing effects; that is, effects on the respondents' stated attitudes caused by question wording and context. The purpose of this study was to demonstrate and measure such framing effects. Survey experiment in which an eight-question survey on attitudes towards assisted dying was distributed to Norwegian citizens through a web-based panel. Two variations of question wording as well as two variations of question order were employed. Respondents were randomized to receive one of four questionnaire versions. Three thousand and fifty responses were received. There were moderate to large question wording and question order effects. A majority of Norwegian citizens favour the legalization of assisted dying for patients with terminal or chronic disease. Stakeholders in the assisted dying debate need to acknowledge potential framing effects, and accordingly should interpret survey results with caution. The same holds for researchers who conduct attitude surveys in the field of bioethics.

Pericardial adipose tissue and the metabolic syndrome is increased in patients with chronic major depressive disorder compared to acute depression and controls.

Science.gov (United States)

Kahl, K G; Herrmann, J; Stubbs, B; Krüger, T H C; Cordes, J; Deuschle, M; Schweiger, U; Hüper, K; Helm, S; Birkenstock, A; Hartung, D

2017-01-04

Major depressive disorder (MDD) is associated with an estimated fourfold risk for premature death, largely attributed to cardiovascular disorders. Pericardial adipose tissue (PAT), a fat compartment surrounding the heart, has been implicated in the development of coronary artery disease. An unanswered question is whether people with chronic MDD are more likely to have elevated PAT volumes versus acute MDD and controls (CTRL). The study group consists of sixteen patients with chronic MDD, thirty-four patients with acute MDD, and twenty-five CTRL. PAT and adrenal gland volume were measured by magnetic resonance tomography. Additional measures comprised factors of the metabolic syndrome, cortisol, relative insulin resistance, and pro-inflammatory cytokines (interleukin-6; IL-6 and tumor necrosis factor-α, TNF-α). PAT volumes were significantly increased in patients with chronic MDD>patients with acute MDD>CTRL. Adrenal gland volume was slightly enlarged in patients with chronic MDD>acute MDD>CTRL, although this difference failed to reach significance. The PAT volume was correlated with adrenal gland volume, and cortisol concentrations were correlated with depression severity, measured by BDI-2 and MADRS. Group differences were found concerning the rate of the metabolic syndrome, being most frequent in chronic MDD>acute MDD>CTRL. Further findings comprised increased fasting cortisol, increased TNF-α concentration, and decreased physical activity level in MDD compared to CTRL. Our results extend the existing literature in demonstrating that patients with chronic MDD have the highest risk for developing cardiovascular disorders, indicated by the highest PAT volume and prevalence of metabolic syndrome. The correlation of PAT with adrenal gland volume underscores the role of the hypothalamus-pituitary-adrenal system as mediator for body-composition changes. Metabolic monitoring, health advices and motivation for the improvement of physical fitness may be recommended in

Neutron Crystallography, Molecular Dynamics, and Quantum Mechanics Studies of the Nature of Hydrogen Bonding in Cellulose I beta

Science.gov (United States)

In the crystal structure of cellulose Ibeta, disordered hydrogen (H) bonding can be represented by the average of two mutually exclusive H bonding schemes that have been designated A and B. An unanswered question is whether A and B interconvert dynamically, or whether they are static but present in ...

Social Analogical Reasoning in School-Aged Children with Autism Spectrum Disorder and Typically Developing Peers

Science.gov (United States)

Green, Adam E.; Kenworthy, Lauren; Gallagher, Natalie M.; Antezana, Ligia; Mosner, Maya G.; Krieg, Samantha; Dudley, Katherina; Ratto, Allison; Yerys, Benjamin E.

2017-01-01

Analogical reasoning is an important mechanism for social cognition in typically developing children, and recent evidence suggests that some forms of analogical reasoning may be preserved in autism spectrum disorder. An unanswered question is whether children with autism spectrum disorder can apply analogical reasoning to social information. In…

Leadership of public health facilities in different climes | Nigerian ...

African Journals Online (AJOL)

In view of perceived marginalization of allied health professionals (AHPs) by the medical doctors, there are agitations by them for appointment to the position of the Medical Directors of hospitals. There are however unanswered questions. This article appraises the current situation and compares what is being done in ...

The value of cancer antigen 125 (CA 125) during treatment and follow-up of patients with ovarian cancer

NARCIS (Netherlands)

deBruijn, HWA; vanderZee, AGJ; Aalders, JG

Although the nature of the cancer antigen 125 leaves many questions unanswered, the use of serum measurements as a means to assess the response to surgery and chemotherapy in ovarian cancer is now well documented. Good prognostic significance is attributed to a rapid decline in cancer antigen 125

Continuous gradient temperature Raman spectroscopy of n-6 DPA and DHA from -100 C to 20°C

Science.gov (United States)

One of the great unanswered questions with respect to biological science in general is the absolute necessity of DHA in fast signal processing tissues. N-6 DPA, with just one less diene, group, is fairly abundant in terrestrial food chains yet cannot substitute for DHA. Gradient Temperature Raman sp...

Adaptive Advice in Learning With a Computer-Based Knowledge Management Simulation Game

NARCIS (Netherlands)

Leemkuil, Hendrik H.; de Jong, Anthonius J.M.

2012-01-01

Despite the long tradition of game-based learning, there are still many unanswered questions regarding the instructional design of educational games. An important issue is the support that learners can be given in a game to enhance their learning. One recommended type of support is “advice,” which

elements for a theology of care

African Journals Online (AJOL)

The novel – one million copies sold and made into a successful movie in 19811 – has had an .... being is a mother's child: I am being cared for, therefore I am. Care has a ..... We have learn to live with unanswered questions.11. But thinking the ...

Twenty years of research on fungal-plant interactions on Lyman Glacier forefront—lessons learned and questions yet unanswered

Science.gov (United States)

Ari Jumpponen; Shawn P. Brown; James M. Trappe; Efrén Cázares; Rauni. Strömmer

2012-01-01

Retreating glaciers and the periglacial areas that they vacate produce a harsh environment of extreme radiation, nutrient limitations and temperature oscillations. They provide a model system for studying mechanisms that drive the establishment and early assembly of communities. Here, we synthesize more than 20 years of research at the Lyman Glacier forefront in the...

Ten-year assessment of the 100 priority questions for global biodiversity conservation.

Science.gov (United States)

Jucker, Tommaso; Wintle, Bonnie; Shackelford, Gorm; Bocquillon, Pierre; Geffert, Jan Laurens; Kasoar, Tim; Kovacs, Eszter; Mumby, Hannah S; Orland, Chloé; Schleicher, Judith; Tew, Eleanor R; Zabala, Aiora; Amano, Tatsuya; Bell, Alexandra; Bongalov, Boris; Chambers, Josephine M; Corrigan, Colleen; Durán, América P; Duvic-Paoli, Leslie-Anne; Emilson, Caroline; da Silva, Jéssica Fonseca; Garnett, Emma E; Green, Elizabeth J; Guth, Miriam K; Hacket-Pain, Andrew; Hinsley, Amy; Igea, Javier; Kunz, Martina; Luke, Sarah H; Lynam, William; Martin, Philip A; Nunes, Matheus H; Ockendon, Nancy; Pavitt, Aly; Payne, Charlotte L R; Plutshack, Victoria; Rademacher, Tim T; Robertson, Rebecca J; Rose, David C; Serban, Anca; Simmons, Benno I; Emilson, Erik J S; Tayleur, Catherine; Wordley, Claire F R; Mukherjee, Nibedita

2018-06-20

In 2008, a group of conservation scientists compiled a list of 100 priority questions for the conservation of the world's biodiversity [Sutherland et al. (2009) Conservation Biology, 23, 557-567]. However, now almost a decade later, no one has yet published a study gauging how much progress has been made in addressing these 100 high-priority questions in the peer-reviewed literature. Here we take a first step toward re-examining the 100 questions and identify key knowledge gaps that still remain. Through a combination of a questionnaire and a literature review, we evaluated each of the 100 questions on the basis of two criteria: relevance and effort. We defined highly-relevant questions as those which - if answered - would have the greatest impact on global biodiversity conservation, while effort was quantified based on the number of review publications addressing a particular question, which we used as a proxy for research effort. Using this approach we identified a set of questions that, despite being perceived as highly relevant, have been the focus of relatively few review publications over the past ten years. These questions covered a broad range of topics but predominantly tackled three major themes: the conservation and management of freshwater ecosystems, the role of societal structures in shaping interactions between people and the environment, and the impacts of conservation interventions. We see these questions as important knowledge gaps that have so far received insufficient attention and may need to be prioritised in future research. This article is protected by copyright. All rights reserved. This article is protected by copyright. All rights reserved.

The emergence of cooking in Southwest Asia

OpenAIRE

Wright, Katherine

2004-01-01

There has been surprisingly little systematic study by prehistorians of how in the distant past people cooked and consumed food. There are many unanswered questions. For example, how did cooking emerge and affect human evolution, how did it change with the advent of farming, when did kitchens first appear and who built the earliest known ovens? Research on Palaeolithic and Neolithic food preparation and consumption is now beginning to suggest answers to such questions.

Self-directed questions to improve students' ability in solving chemical problems

Science.gov (United States)

Sanjaya, Rahmat Eko; Muna, Khairiatul; Suharto, Bambang; Syahmani

2017-12-01

Students' ability in solving chemical problems is seen from their ability to solve chemicals' non-routine problems. It is due to learning faced directly on non-routine problems will generate a meaningful learning for students. Observations in Banjarmasin Public High School 1 (SMA Negeri 1 Banjarmasin) showed that students did not give the expected results when they were given the non-routine problems. Learning activities by emphasizing problem solving was implemented based on the existence of knowledge about cognition and regulation of cognition. Both of these elements are components of metacognition. The self-directed question is a strategy that involves metacognition in solving chemical problems. This research was carried out using classroom action research design in two cycles. Each cycle consists of four stages: planning, action, observation and reflection. The subjects were 34 students of grade XI-4 at majoring science (IPA) of SMA Negeri 1 Banjarmasin. The data were collected using tests of the students' ability in problem solving and non-tests instrument to know the process of implementation of the actions. Data were analyzed with descriptivequantitativeand qualitative analysis. The ability of students in solving chemical problems has increased from an average of 37.96 in cycle I became 61.83 in cycle II. Students' ability to solve chemical problems is viewed based on their ability to answer self-directed questions. Students' ability in comprehension questions increased from 73.04 in the cycle I became 96.32 in cycle II. Connection and strategic questions increased from 54.17 and 16.50 on cycle I became 63.73 and 55.23 on cycle II respectively. In cycle I, reflection questions were 26.96 and elevated into 36.27 in cycle II. The self-directed questions have the ability to help students to solve chemical problems through metacognition questions. Those questions guide students to find solutions in solving chemical problems.

Asking a Great Question: A Librarian Teaches Questioning Skills to First-Year Medical Students.

Science.gov (United States)

Adams, Nancy E

2015-01-01

In a single one-hour session, first-year medical students were taught a framework for differentiating between lower-order questions that lead to knowledge of facts and higher-order questions that lead to integration of concepts and deeper learning, thereby preparing them for problem-based learning (PBL). Students generated lists of questions in response to an assertion prompt and categorized them according to Bloom's Taxonomy. These data were analyzed in addition to data from the course exam, which asked them to formulate a higher-level question in response to a prompt. Categorizing questions according to Bloom's Taxonomy was a more difficult task for students than was formulating higher-order questions. Students reported that the skills that they learned were used in subsequent PBL sessions to formulate higher-order learning objectives that integrated new and previously-learned concepts.

Efficient question answering with question decomposition and multiple answer streams

OpenAIRE

Hartrumpf, Sven; Glöckner, Ingo; Leveling, Johannes

2009-01-01

The German question answering (QA) system IRSAW (formerly: InSicht) participated in QA@CLEF for the fth time. IRSAW was introduced in 2007 by integrating the deep answer producer InSicht, several shallow answer producers, and a logical validator. InSicht builds on a deep QA approach: it transforms documents to semantic representations using a parser, draws inferences on semantic representations with rules, and matches semantic representations derived from questions and documents. InS...

CAT questions and answers

International Nuclear Information System (INIS)

1993-02-01

This document, prepared in February 1993, addresses the most common questions asked by APS Collaborative Access Teams (CATs). The answers represent the best judgment on the part of the APS at this time. In some cases, details are provided in separate documents to be supplied by the APS. Some of the answers are brief because details are not yet available. The questions are separated into five categories representing different aspects of CAT interactions with the APS: (1) Memorandum of Understanding (MOU), (2) CAT Beamline Review and Construction, (3) CAT Beamline Safety, (4) CAT Beamline Operations, and (5) Miscellaneous. The APS plans to generate similar documents as needed to both address new questions and clarify answers to present questions

Toward Question-Asking Machines: The Logic of Questions and the Inquiry Calculus

Science.gov (United States)

Knuth,Kevin H.

2005-01-01

For over a century, the study of logic has focused on the algebra of logical statements. This work, first performed by George Boole, has led to the development of modern computers, and was shown by Richard T. Cox to be the foundation of Bayesian inference. Meanwhile the logic of questions has been much neglected. For our computing machines to be truly intelligent, they need to be able to ask relevant questions. In this paper I will show how the Boolean lattice of logical statements gives rise to the free distributive lattice of questions thus defining their algebra. Furthermore, there exists a quantity analogous to probability, called relevance, which quantifies the degree to which one question answers another. I will show that relevance is not only a natural generalization of information theory, but also forms its foundation.

In-Situ XRD during Electrochemical CO Reduction on Cu

DEFF Research Database (Denmark)

Bertheussen, Erlend; Scott, Søren Bertelsen; Hogg, Thomas

2018-01-01

Almost all-successful CO2 and CO reduction catalysts to higher chain carbons are based on copper1, however various facets and pre-treatments of copper have shown to give a wide variety of product selectivity.2,3 Currently there are many unanswered questions regarding active sites and mechanisms t...

What Makes a Motivating Teacher? Teachers' Motivation and Beliefs as Predictors of Their Autonomy-Supportive Style

Science.gov (United States)

Katz, Idit; Shahar, Bat-Hen

2015-01-01

Findings from several studies suggest that teachers who embrace an autonomy-supportive style vis-à-vis their students promote student motivation. However, the question of what makes teachers adopt this supportive style remains unanswered. Using Self-Determination Theory as a framework, we suggest that teachers' own motivation and their beliefs…

Self Perceived Leadership Styles of Male and Female Superintendents in Wisconsin Public Schools

Science.gov (United States)

Rieckmann, Kelly Renée

2016-01-01

The number of female superintendents in Wisconsin public schools remains disproportionately low compared to males. With research supporting a connection between female leaders and transformational leadership, the question as to why more females do not enter the realm of leadership and how they see themselves as leaders remains unanswered. This…

The Effect of a Robot's Social Character on Children Task Engagement: Peer Versus Tutor

NARCIS (Netherlands)

Zaga, Cristina; Lohse, M.; Truong, Khiet Phuong; Evers, Vanessa; Tapus, Adriana; André, Elisabeth; Martin, Jean-Claude; Ferland, François; Ammi, Mehdi

2015-01-01

An increasing number of applications for social robots focuses on learning and playing with children. One of the unanswered questions is what kind of social character a robot should have in order to positively engage children in a task. In this paper, we present a study on the effect of two

Comparative MD analysis of the stability of transthyretin providing insight into the fibrillation mechanism

DEFF Research Database (Denmark)

Sørensen, Jesper; Hamelberg, Donald; Schiøtt, Birgit

2007-01-01

Proteins can misfold and aggregate, which is believed to be the cause of a variety of diseases, affecting very diverse organs in the body. Many questions about the nature of aggregation and the proteins that are involved in these events are still left unanswered. One of the proteins that is known...

Inclusive Research and Inclusive Education: Why Connecting Them Makes Sense for Teachers' and Learners' Democratic Development of Education

Science.gov (United States)

Nind, Melanie

2014-01-01

Following pushes from the disability movement(s) and increased interest in children and young people becoming involved in research concerning them, inclusive research is growing within and beyond education establishments. Yet this arena is alive with interesting and largely unanswered questions. This paper discusses some of them: What do inclusive…

Developing an Undergraduate Information Systems Security Track

Science.gov (United States)

Sharma, Aditya; Murphy, Marianne C.; Rosso, Mark A.; Grant, Donna

2013-01-01

Information Systems Security as a specialized area of study has mostly been taught at the graduate level. This paper highlights the efforts of establishing an Information Systems (IS) Security track at the undergraduate level. As there were many unanswered questions and concerns regarding the Security curriculum, focus areas, the benefit of…

A Culture Model as Mediator and Repository Source for Innovation

Science.gov (United States)

Mohammadisadr, Mohammad; Siadat, Seyed Ali; Azizollah, Arbabisarjou; Ebrahim, Ebrahimitabas

2012-01-01

As innovation has become one of the most important competitive advantages, academic practitioner's interest in the matter has increased. But, still the question "why lots of organizations fail in their path of article to be innovative" is remained unanswered. In this, among many factors influencing innovation capacity of an organization;…

Tone Discrimination as a Window into Acoustic Perceptual Deficits in Parkinson's Disease

Science.gov (United States)

Troche, Joshua; Troche, Michelle S.; Berkowitz, Rebecca; Grossman, Murray; Reilly, Jamie

2012-01-01

Purpose: Deficits in auditory perception compromise a range of linguistic processes in persons with Parkinson's disease (PD), including speech perception and sensitivity to affective and linguistic prosody. An unanswered question is whether this deficit exists not only at the level of speech perception, but also at a more pervasive level of…

Asking the Right Questions

DEFF Research Database (Denmark)

Richter, Line

Based on fieldwork in Mali this paper discusses the role of anthropology (and the anthropologist) in a large public health research project on children's health. In the uncertainty and disquiet that comes with the battle to combat and avoid diseases in a setting where poverty and abysmal diseases......, is the ability to move beyond even the best hidden assumptions and question our own questions, thereby enabling us to ask the right questions....

A beautiful question finding nature’s deep design

CERN Document Server

Wilczek, Frank

2015-01-01

Artists as well as scientists throughout human history have pondered this “beautiful question.” With Nobel laureate Frank Wilczek as your guide, embark on a voyage of related discoveries, from Plato and Pythagoras up to the present. Wilczek’s groundbreaking work in quantum physics was inspired by his intuition to look for a deeper order of beauty in nature. In fact, every major advance in his career came from this intuition: to assume that the universe embodies beautiful forms, forms whose hallmarks are symmetry—harmony, balance, proportion—and economy. There are other meanings of “beauty,” but this is the deep logic of the universe—and it is no accident that it is also at the heart of what we find aesthetically pleasing and inspiring. Wilczek is hardly alone among great scientists in charting his course using beauty as his compass. As he reveals in A Beautiful Question, this has been the heart of scientific pursuit from Pythagoras, the ancient Greek who was the first to argue that “all thi...

Female sex work and international sport events - no major changes in demand or supply of paid sex during the 2010 Soccer World Cup: a cross-sectional study

Science.gov (United States)

2012-01-01

Background Important unanswered questions remain on the impact of international sporting events on the sex industry. Speculation about increased demand and supply of sex work often generates significant attention, but also additional funding for HIV programmes. This study assessed whether changes occurred in the demand and supply of paid sex during the 2010 Soccer World Cup in South Africa. Methods Trained sex worker interviewers conducted face-to-face semi-structured interviews among consenting female sex workers during May-September 2010. Using bivariate analyses we compared supply, demand, sexual risk-taking, and police and health services contact pre-World Cup, to levels during the World Cup and after the event. Results No increases were detected in indicators of sex work supply, including the proportion of sex workers newly arrived in the city ( 92.4% in all phases). Health-care utilisation decreased non-significantly from the pre- to during World Cup period (62.4% to 57.0%; P = 0.075). Across all periods, about thirty percent of participants had interacted with police in the preceding month, two thirds of whom had negative interactions. Conclusions Contrary to public opinion, no major increases were detected in the demand or supply of paid sex during the World Cup. Although the study design employed was unable to select population-based samples, these findings do not support the public concern and media speculation prior to the event, but rather signal a missed opportunity for public health action. Given the media attention on sex work, future sporting events offer strategic opportunities to implement services for sex workers and their clients, especially as health service utilisation might decrease in this period. PMID:22967260

Developmental regression in autism: research and conceptual questions

Directory of Open Access Journals (Sweden)

Carolina Lampreia

2013-11-01

Full Text Available The subject of developmental regression in autism has gained importance and a growing number of studies have been conducted in recent years. It is a major issue indicating that there is not a unique form of autism onset. However the phenomenon itself and the concept of regression have been the subject of some debate: there is no consensus on the existence of regression, as there is no consensus on its definition. The aim of this paper is to review the research literature in this area and to introduce some conceptual questions about its existence and its definition.

The emergence of cooking in Southwest Asia

Directory of Open Access Journals (Sweden)

Katherine Wright

2004-08-01

Full Text Available There has been surprisingly little systematic study by prehistorians of how in the distant past people cooked and consumed food. There are many unanswered questions. For example, how did cooking emerge and affect human evolution, how did it change with the advent of farming, when did kitchens first appear and who built the earliest known ovens? Research on Palaeolithic and Neolithic food preparation and consumption is now beginning to suggest answers to such questions.

Non-SUSY Beyond Standard Model Searches: Recent Results from ATLAS and CMS

OpenAIRE

Malek, Fairouz

2015-01-01

The Standard Model of particle physics is a sensational success, especially since the discovery of the 125 GeV Higgs boson. However, there are still numerous unanswered questions. Why is the Higgs so light? Do the interactions couplings unify and how can gravity be included? Why three fermion generations? What is dark matter? Theories Beyond the Standard Model (BSM), such as Grand Unified Theories, Extra Dimensions or Technicolour are trying to answer these questions. In this proceedings, we ...

Live your questions now

OpenAIRE

Brownrigg, Jenny

2016-01-01

'Live Your Questions Now' is a case study for Cubitt Education's publication 'Aging in Public: creative practice in ageing and the public realm from across the UK', edited by Daniel Baker and published by Cubitt Gallery, Studios and Education, London in 2016. The publication was linked to Cubitt's programme 'Public Wisdom' (2011-2015). My case study is about 'Live your questions now', a group exhibition I curated in 2011 for Mackintosh Museum, The Glasgow School of Art. 'Live your questions n...

Management of Adult Syphilis: Key Questions to Inform the 2015 Centers for Disease Control and Prevention Sexually Transmitted Diseases Treatment Guidelines.

Science.gov (United States)

Ghanem, Khalil G

2015-12-15

vertical transmission from mother to infant is low. Several important questions regarding the management of syphilis remain unanswered and should be a priority for future research. © The Author 2015. Published by Oxford University Press on behalf of the Infectious Diseases Society of America. All rights reserved. For Permissions, please e-mail: journals.permissions@oup.com.

Business rescue: How can its success be evaluated at company level?

African Journals Online (AJOL)

The question of what constitutes a successful business rescue is a very topical and unanswered one. Reports on success are contradictory and seem to lack a set of standardised evaluation criteria. The purpose of this article is to investigate how business rescue success is evaluated internationally in order to develop a set ...

Intuition, Reason, and Metacognition

Science.gov (United States)

Thompson, Valerie A.; Prowse Turner, Jamie A.; Pennycook, Gordon

2011-01-01

Dual Process Theories (DPT) of reasoning posit that judgments are mediated by both fast, automatic processes and more deliberate, analytic ones. A critical, but unanswered question concerns the issue of monitoring and control: When do reasoners rely on the first, intuitive output and when do they engage more effortful thinking? We hypothesised…

Hillslope threshold response to rainfall: (1) a field based forensic approach

Science.gov (United States)

Chris B. Graham; Ross A. Woods; Jeffrey J. McDonnell

2010-01-01

Hillslope threshold response to storm rainfall is poorly understood. Basic questions regarding the type, location, and flow dynamics of lateral, subsurface flow remain unanswered, even at our most intensively studied field sites. Here we apply a forensic approach where we combined irrigation and excavation experiments at the well studied Maimai hillslope to determine...

The Time Parents and Children Spend Together.

Science.gov (United States)

Ziegler, Mark E.

Questions about how parents' childrearing time becomes associated with different developmental outcomes and about the relative importance of the quantity and quality of shared parent/child time remain largely unanswered. A study explored such associations in a sample of 48 white middle class third and fourth graders (24 boys and 24 girls) and…

Receptivity to Learner-Driven Feedback in EAP

Science.gov (United States)

Maas, Clare

2017-01-01

There is still debate surrounding what constitutes the most effective feedback on EFL learners' writing, particularly in English for Academic Purposes (EAP) settings. Unanswered questions are found in the literature on topics such as the best formats for feedback, the role of technology, authors' authority over written texts, and ways of helping…

A Technique Socratic Questioning-Guided Discovery

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M. Hakan Türkçapar

2012-03-01

Full Text Available “Socratic Method” is a way of teaching philosophical thinking and knowledge by asking questions which was used by antique period greek philosopher Socrates. Socrates was teaching knowledge to his followers by asking questions and the conversation between them was named “Socratic Dialogues”. In this meaning, no novel knowledge is taught to the individual but only what is formerly known is reminded and rediscovered. The form of socratic questioning which is used during the process of cognitive behavioral therapy is known as Guided Discovery. In this method it is aimed to make the client notice the piece of knowledge which he could notice but is not aware with a series of questions. Socratic method or guided discovery consists of several steps which are: Identifying the problem by listening to the client and making reflections, finding alternatives by examining and evaluating, reidentification by using the newly found information and questioning the old distorted belief and reaching to a conclusion and applying it. Question types used during these procedures are, questions for gaining information, questions revealing the meanings, questions revealing the beliefs, questions about behaviours during the similar past experiences, analyse questions and analytic synthesis questions. In order to make the patient feel understood it is important to be empathetic and summarising the problem during the interview. In this text, steps of Socratic Questioning-Guided Discovery will be reviewed with sample dialogues after each step

The European Union, the ESDP, and the question of Turkey /

OpenAIRE

Taylor, Alistair

2005-01-01

This paper analyses the potential contribution in terms of crude capabilities that Turkey could bring to the European Union’s ESDP security framework. The history of the European Union’s security aspirations and the security policy preferences of the major actors in European security will also be examined as a way of framing the question of Turkey's potential role within the emerging European security and defense framework. The second chapter will look at how European security has evolved fro...

Meiotic faults as a major cause of offspring inviability

DEFF Research Database (Denmark)

Levitis, Daniel; Zimmerman, Kolea; Pringle, Anne

2014-01-01

, this result demonstrates that failures associated with meiosis are a major cause of offspring inviability not only for meiotic parthenogenesis, but for sexual reproducers such as humans. Meiosis is necessary for genetic recombination in eukaryotes, but is vestigial, and costly, in parthenogens. The question...... range of organisms....

Frequent Questions on Recycling

Science.gov (United States)

This is a list of frequent questions on recycling, broken down into five categories. These are answers to common questions that EPA has received from press and web inquiries. This list is located on the Reduce, Reuse, Recycle website.

From Cultural Imperialists to Takeover Victims? Questions on Hollywood's Buyouts from the Critical Tradition.

Science.gov (United States)

McAnany, Emile G.; Wilkinson, Kenton T.

1992-01-01

Examines the history of the cultural imperialism debate. Reviews international questions raised concerning the role and influence of the still-popular Hollywood products. Examines changing ownership patterns in Hollywood (buyouts by major foreign interests). Notes important trends, and suggests areas for critical research. (SR)

Examining the Impact of Question Surface Features on Students’ Answers to Constructed-Response Questions on Photosynthesis

Science.gov (United States)

Weston, Michele; Haudek, Kevin C.; Prevost, Luanna; Urban-Lurain, Mark; Merrill, John

2015-01-01

One challenge in science education assessment is that students often focus on surface features of questions rather than the underlying scientific principles. We investigated how student written responses to constructed-response questions about photosynthesis vary based on two surface features of the question: the species of plant and the order of two question prompts. We asked four versions of the question with different combinations of the two plant species and order of prompts in an introductory cell biology course. We found that there was not a significant difference in the content of student responses to versions of the question stem with different species or order of prompts, using both computerized lexical analysis and expert scoring. We conducted 20 face-to-face interviews with students to further probe the effects of question wording on student responses. During the interviews, we found that students thought that the plant species was neither relevant nor confusing when answering the question. Students identified the prompts as both relevant and confusing. However, this confusion was not specific to a single version. PMID:25999312

Biology Question Generation from a Semantic Network

Science.gov (United States)

Zhang, Lishan

Science instructors need questions for use in exams, homework assignments, class discussions, reviews, and other instructional activities. Textbooks never have enough questions, so instructors must find them from other sources or generate their own questions. In order to supply instructors with biology questions, a semantic network approach was developed for generating open response biology questions. The generated questions were compared to professional authorized questions. To boost students' learning experience, adaptive selection was built on the generated questions. Bayesian Knowledge Tracing was used as embedded assessment of the student's current competence so that a suitable question could be selected based on the student's previous performance. A between-subjects experiment with 42 participants was performed, where half of the participants studied with adaptive selected questions and the rest studied with mal-adaptive order of questions. Both groups significantly improved their test scores, and the participants in adaptive group registered larger learning gains than participants in the control group. To explore the possibility of generating rich instructional feedback for machine-generated questions, a question-paragraph mapping task was identified. Given a set of questions and a list of paragraphs for a textbook, the goal of the task was to map the related paragraphs to each question. An algorithm was developed whose performance was comparable to human annotators. A multiple-choice question with high quality distractors (incorrect answers) can be pedagogically valuable as well as being much easier to grade than open-response questions. Thus, an algorithm was developed to generate good distractors for multiple-choice questions. The machine-generated multiple-choice questions were compared to human-generated questions in terms of three measures: question difficulty, question discrimination and distractor usefulness. By recruiting 200 participants from

The Spanish Exile Put to the Test: Polemics in the Pres between Indalecio Prieto and the Mexican Alfonso Junco regarding the gold aboard the yacht “Vita”

Directory of Open Access Journals (Sweden)

Carlos Sola Ayape

2014-04-01

Full Text Available In November, 1946, just a few days before Miguel Alemán took charge as new president of Mexico, the Mexican press –concretely, the newspaper Novedades– would become an ink-and-paper stage for an important dialectic dispute between Alfonso Junco, a Mexican Catholic hispanicist, and Indalecio Prieto, a Spanish Socialist exile and undoubtedly, one of the most important political references of the Second Spanish Republic. Among the many questions left unanswered, there appeared the edges of one of the major issues that haunted the Spanish pilgrimage during its diaspora: the treasures removed before the end of the Civil War. This was so because the legitimation of Franco's regime was also built from the constant pages of accusations towards the “reds” in exile.

Planetary Protection and Mars Special Regions--A Suggestion for Updating the Definition.

Science.gov (United States)

Rettberg, Petra; Anesio, Alexandre M; Baker, Victor R; Baross, John A; Cady, Sherry L; Detsis, Emmanouil; Foreman, Christine M; Hauber, Ernst; Ori, Gian Gabriele; Pearce, David A; Renno, Nilton O; Ruvkun, Gary; Sattler, Birgit; Saunders, Mark P; Smith, David H; Wagner, Dirk; Westall, Frances

2016-02-01

We highlight the role of COSPAR and the scientific community in defining and updating the framework of planetary protection. Specifically, we focus on Mars "Special Regions," areas where strict planetary protection measures have to be applied before a spacecraft can explore them, given the existence of environmental conditions that may be conducive to terrestrial microbial growth. We outline the history of the concept of Special Regions and inform on recent developments regarding the COSPAR policy, namely, the MEPAG SR-SAG2 review and the Academies and ESF joint committee report on Mars Special Regions. We present some new issues that necessitate the update of the current policy and provide suggestions for new definitions of Special Regions. We conclude with the current major scientific questions that remain unanswered regarding Mars Special Regions.

Post-Traumatic Hypopituitarism—Who Should Be Screened, When, and How?

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Mark Quinn

2018-02-01

Full Text Available Traumatic brain injury (TBI remains a major, global public health concern. Over the last 15 years, a significant body of evidence has emerged demonstrating that post-traumatic hypopituitarism (PTHP is a common and clinically significant consequence of TBI. Non-specific symptomology and the lack of an agreed approach to screening for PTHP has led to significant under-diagnosis of this debilitating disease. In this review, we will discuss the frequency and clinical significance of acute and chronic PTHP as described in the current literature highlighting the evidence base for screening and hormone replacement in these patients. We will also offer a pragmatic approach to identifying relevant anterior pituitary dysfunction after TBI and a follow-up strategy for those patients. Specific controversies and remaining unanswered questions will be addressed.

Preparing Teachers to Integrate Web 2.0 in School Practice: Toward a Framework for Pedagogy 2.0

Science.gov (United States)

Jimoyiannis, Athanassios; Tsiotakis, Panagiotis; Roussinos, Dimitrios; Siorenta, Anastasia

2013-01-01

Web 2.0 has captured the interest and the imagination of both educators and researchers while it is expected to exert a significant impact on instruction and learning, in the context of the 21st century education. Hailed as an open collaborative learning space, many questions remain unanswered regarding the appropriate teacher preparation and the…

Do Mobile Learning Devices Enhance Learning in Higher Education Anatomy Classrooms?

Science.gov (United States)

Wilkinson, Kate; Barter, Phil

2015-01-01

Recently there has been an increased volume of research and practice of mobile Learning (mLearning) and in particular of the tablet device. The question of how, when and where to best incorporate the tablet device into the learning environment in Higher Education remains largely unanswered. The article presents the findings of an empirical study…

Outrages Against Personal Dignity: Rationalizing Abuse and Torture in the War on Terror

Science.gov (United States)

Gregory Hooks; Clayton Mosher

2005-01-01

The outrage over revelations of torture and abuse at Abu Ghraib prison has faded from public discourse, but a number of questions remain unanswered. This paper criticizes official rationalizations offered for the abuse. We make the case that these abuses are systemic, resulting from dehumanization of the enemy and the long reliance on and…

Questions for Music Education Research

Science.gov (United States)

Jorgensen, Estelle R.

2008-01-01

In addressing the question-set "What questions do music education researchers need to address?", an illustrative list of juxtaposed descriptive and normative questions is sketched as follows: What are and should be the dimensions of music education? What are and should be the institutional agencies of music education? What are and should be the…

Dynamic Question Ordering in Online Surveys

Directory of Open Access Journals (Sweden)

Early Kirstin

2017-09-01

Full Text Available Online surveys have the potential to support adaptive questions, where later questions depend on earlier responses. Past work has taken a rule-based approach, uniformly across all respondents. We envision a richer interpretation of adaptive questions, which we call Dynamic Question Ordering (DQO, where question order is personalized. Such an approach could increase engagement, and therefore response rate, as well as imputation quality. We present a DQO framework to improve survey completion and imputation. In the general survey-taking setting, we want to maximize survey completion, and so we focus on ordering questions to engage the respondent and collect hopefully all information, or at least the information that most characterizes the respondent, for accurate imputations. In another scenario, our goal is to provide a personalized prediction. Since it is possible to give reasonable predictions with only a subset of questions, we are not concerned with motivating users to answer all questions. Instead, we want to order questions to get information that reduces prediction uncertainty, while not being too burdensome. We illustrate this framework with two case studies, for the prediction and survey-taking settings. We also discuss DQO for national surveys and consider connections between our statistics-based question-ordering approach and cognitive survey methodology.

Physical Activity and the Prevention of Hypertension

Science.gov (United States)

Diaz, Keith M.; Shimbo, Daichi

2013-01-01

As the worldwide prevalence of hypertension continues to increase, the primary prevention of hypertension has become an important global public health initiative. Physical activity is commonly recommended as an important lifestyle modification that may aid in the prevention of hypertension. Recent epidemiologic evidence has demonstrated a consistent, temporal, and dose-dependent relationship between physical activity and the development of hypertension. Experimental evidence from interventional studies have further confirmed a relationship between physical activity and hypertension as the favorable effects of exercise on blood pressure reduction have been well characterized in recent years. Despite the available evidence strongly supporting a role for physical activity in the prevention of hypertension, many unanswered questions regarding the protective benefits of physical activity in high-risk individuals, the factors that may moderate the relationship between physical activity and hypertension, and the optimal prescription for hypertension prevention remain. We review the most recent evidence for the role of physical activity in the prevention of hypertension and discuss recent studies that have sought to address these unanswered questions. PMID:24052212

Repetitive Questioning Exasperates Caregivers

Directory of Open Access Journals (Sweden)

R. C. Hamdy MD

2018-01-01

Full Text Available Repetitive questioning is due to an impaired episodic memory and is a frequent, often presenting, problem in patients with Alzheimer’s disease (amnestic type. It is due to the patients’ difficulties learning new information, retaining it, and recalling it, and is often aggravated by a poor attention span and easy distractibility. A number of factors may trigger and maintain repetitive questioning. Caregivers should try to identify and address these triggers. In the case discussion presented, it is due to the patient’s concerns about her and her family’s safety triggered by watching a particularly violent movie aired on TV. What went wrong in the patient/caregiver interaction and how it could have been avoided or averted are explored. Also reviewed are the impact of repetitive questioning, the challenges it raises for caregivers, and some effective intervention strategies that may be useful to diffuse the angst that caregivers experience with repetitive questioning.

Enterprise architecture for business success

CERN Document Server

Wijegunaratne, Inji; Evans-Greenwood, Peter

2014-01-01

Enterprise Architecture (EA) has evolved to become a prominent presence in today's information systems and technology landscape. The EA discipline is rich in frameworks, methodologies, and the like. However, the question of 'value' for business ;professionals remains largely unanswered - that is, how best can Enterprise Architecture and Enterprise Architects deliver value to the enterprise? Enterprise Architecture for Business Success answers this question. Enterprise Architecture for Business Success is primarily intended for IT professionals working in the area of Enterprise Architectu

Distance teaching using self-marking multiple choice questions.

Science.gov (United States)

Poore, P

1987-01-01

In Papua New Guinea health extension officers receive a 3-year course of training in college, followed by a period of in-service training in hospital. They are then posted to a health center, where they are in charge of all health services within their district. While the health extension officers received an excellent basic training, and were provided with books and appropriate, locally produced texts, they often spent months or even years after graduation in remote rural health centers with little communication from colleagues. This paper describes an attempt to improve communication, and to provide support inexpensively by post. Multiple choice questions, with a system for self-marking, were sent by post to rural health workers. Multiple choice questions are used in the education system in Papua New Guinea, and all health extension officers are familiar with the technique. The most obvious and immediate result was the great enthusiasm shown by the majority of health staff involved. In this way a useful exchange of correspondence was established. With this exchange of information and recognition of each other's problems, the quality of patient care must improve.

Requiring students to have computers: questions for consideration.

Science.gov (United States)

McAuley, R J

1998-06-01

For the past several years a dialogue has been taking place in the offices, lounges, and meeting rooms of medical schools about whether medical students should be required to bring or purchase computers when they enter school. Microcomputers offer educators a unique opportunity to provide students with access to computer-assisted instruction, asynchronous communication, and extensive knowledge bases. However, there is still no evidence attesting to the effectiveness of computers as teaching or learning tools in medical education. The author raises questions that schools need to consider before requiring students to own computers: What kind of computer best suits their needs? What might impede using computers to teach? And who is currently requiring computers? In addressing the last question, the author presents information about 15 North American schools that currently require their students to have computers, reporting each school's software and hardware requirements; how each expects students to use the computers; and who covers the cost of the computers (the students or the school). Finally, he argues that major institutional commitment is needed for computers to be successfully integrated into any medical school curriculum.

Assessing flight safety differences between the United States regional and major airlines

Science.gov (United States)

Sharp, Broderick H.

During 2008, the U.S. domestic airline departures exceeded 28,000 flights per day. Thirty-nine or less than 0.2 of 1% of these flights resulted in operational incidents or accidents. However, even a low percentage of airline accidents and incidents continue to cause human suffering and property loss. The charge of this study was the comparison of U.S. major and regional airline safety histories. The study spans safety events from January 1982 through December 2008. In this quantitative analysis, domestic major and regional airlines were statistically tested for their flight safety differences. Four major airlines and thirty-seven regional airlines qualified for the safety study which compared the airline groups' fatal accidents, incidents, non-fatal accidents, pilot errors, and the remaining six safety event probable cause types. The six other probable cause types are mechanical failure, weather, air traffic control, maintenance, other, and unknown causes. The National Transportation Safety Board investigated each airline safety event, and assigned a probable cause to each event. A sample of 500 events was randomly selected from the 1,391 airlines' accident and incident population. The airline groups' safety event probabilities were estimated using the least squares linear regression. A probability significance level of 5% was chosen to conclude the appropriate research question hypothesis. The airline fatal accidents and incidents probability levels were 1.2% and 0.05% respectively. These two research questions did not reach the 5% significance level threshold. Therefore, the airline groups' fatal accidents and non-destructive incidents probabilities favored the airline groups' safety differences hypothesis. The linear progression estimates for the remaining three research questions were 71.5% for non-fatal accidents, 21.8% for the pilot errors, and 7.4% significance level for the six probable causes. These research questions' linear regressions are greater than

Usage-based vs. rule-based learning: the acquisition of word order in wh-questions in English and Norwegian.

Science.gov (United States)

Westergaard, Marit

2009-11-01

This paper discusses different approaches to language acquisition in relation to children's acquisition of word order in wh-questions in English and Norwegian. While generative models assert that children set major word order parameters and thus acquire a rule of subject-auxiliary inversion or generalized verb second (V2) at an early stage, some constructivist work argues that English-speaking children are simply reproducing frequent wh-word+auxiliary combinations in the input. The paper questions both approaches, re-evaluates some previous work, and provides some further data, concluding that the acquisition of wh-questions must be the result of a rule-based process. Based on variation in adult grammars, a cue-based model to language acquisition is presented, according to which children are sensitive to minor cues in the input, called micro-cues. V2 is not considered to be one major parameter, but several smaller-scale cues, which are responsible for children's lack of syntactic (over-)generalization in the acquisition process.

The Question Complexity Rubric: Development and Application for a National Archive of Astro 101 Multiple-Choice Questions

Science.gov (United States)

Cormier, Sebastien; Prather, E. E.; Brissenden, G.; Collaboration of Astronomy Teaching Scholars CATS

2011-01-01

For the last two years we have been developing an online national archive of multiple-choice questions for use in the Astro 101 classroom. These questions are intended to either supplement an instructor's implementation of Think-Pair-Share or be used for assessment purposes (i.e. exams and homework). In this talk we will describe the development, testing and implementation of the Question Complexity Rubric (QCR), which is designed to guide the ranking of questions in this archive based on their conceptual complexity. Using the QCR, a score is assigned to differentiate each question based on the cognitive steps necessary to comprehensively explain the reasoning pathway to the correct answer. The lowest QCR score is given to questions with a reasoning pathway requiring only declarative knowledge whereas the highest QCR score is given to questions that require multiple pathways of multi-step reasoning. When completed, the online question archive will provide users with the utility to 1) search for and download questions based on subject and average QCR score, 2) use the QCR to score questions, and 3) add their own questions to the archive. We will also discuss other potential applications of the QCR, such as how it informs our work in developing and testing of survey instruments by allowing us to calibrate the range of question complexity. This material is based upon work supported by the National Science Foundation under Grant No. 0715517, a CCLI Phase III Grant for the Collaboration of Astronomy Teaching Scholars (CATS). Any opinions, findings, and conclusions or recommendations expressed in this material are those of the authors and do not necessarily reflect the views of the National Science Foundation.

The Value Question in Metaphysics

Science.gov (United States)

Kahane, Guy

2012-01-01

Much seems to be at stake in metaphysical questions about, for example, God, free will or morality. One thing that could be at stake is the value of the universe we inhabit—how good or bad it is. We can think of competing philosophical positions as describing possibilities, ways the world might turn out to be, and to which value can be assigned. When, for example, people hope that God exists, or fear that we do not possess free will, they express attitudes towards these possibilities, attitudes that presuppose answers to questions about their comparative value. My aim in this paper is to distinguish these evaluative questions from related questions with which they can be confused, to identify structural constraints on their proper pursuit, and to address objections to their very coherence. Answers to such evaluative questions offer one measure of the importance of philosophical disputes. PMID:23024399

The Value Question in Metaphysics.

Science.gov (United States)

Kahane, Guy

2012-07-01

Much seems to be at stake in metaphysical questions about, for example, God, free will or morality. One thing that could be at stake is the value of the universe we inhabit-how good or bad it is. We can think of competing philosophical positions as describing possibilities, ways the world might turn out to be, and to which value can be assigned. When, for example, people hope that God exists, or fear that we do not possess free will, they express attitudes towards these possibilities, attitudes that presuppose answers to questions about their comparative value. My aim in this paper is to distinguish these evaluative questions from related questions with which they can be confused, to identify structural constraints on their proper pursuit, and to address objections to their very coherence. Answers to such evaluative questions offer one measure of the importance of philosophical disputes.

Legal Philosophy - Five Questions

DEFF Research Database (Denmark)

This collection gathers together a host of the most eminent contemporary legal philosophers, who writes about their take on legal philosophy, its fundamental questions and potential.......This collection gathers together a host of the most eminent contemporary legal philosophers, who writes about their take on legal philosophy, its fundamental questions and potential....

An unanswered question in pediatric urology: the post pubertal persistence of prepubertal congenital penile curvature correction by tunical plication.

Science.gov (United States)

Ozkuvanci, Ünsal; Ziylan, Orhan; Dönmez, M Irfan; Yucel, Omer Baris; Oktar, Tayfun; Ander, Haluk; Nane, Ismet

2017-01-01

The aim of this study is to analyze post pubertal results of pre pubertal tunica albuginea plication with non-absorbable sutures in the correction of CPC. The files of patients who underwent tunica albuginea plication without incision (dorsal/lateral) were retrospectively reviewed. Patients younger than 13 years of age at the time of operation and older than 14 years of age in November 2015 were included. Patients with a penile curvature of less than 30 degrees & more than 45 degrees and penile/urethral anomalies were excluded. All of the patients underwent surgery followed by circumcision. The mean age of patients at the time of the operation was 9.7 years (range, 6-13 years). The mean degree of ventral penile curvature measured during the operation was 39 degrees while it was 41 degrees in the lateral curvatures. All of the patients were curvature-free at the end of the operation. At the time of the follow-up examination, the mean age was 16.7 years (range, 14-25 years). Six patients had a straight (0-10 degrees) penis during erection and seven patients had recurrent penile curvatures ranging from 30 to 50 degrees. Pre pubertal tunica albuginea plication of congenital penile curvature (30-45 degrees) with non-absorbable sutures performed without incision is a minimal invasive method especially when performed during circumcision. However, recurrence might be observed in half of the patients after puberty. Copyright® by the International Brazilian Journal of Urology.

An unanswered question in pediatric urology: the post pubertal persistence of prepubertal congenital penile curvature correction by tunical plication

Directory of Open Access Journals (Sweden)

Ünsal Ozkuvanci

Full Text Available ABSTRACT Objective: The aim of this study is to analyze post pubertal results of pre pubertal tunica albuginea plication with non-absorbable sutures in the correction of CPC. Materials and Methods: The files of patients who underwent tunica albuginea plication without incision (dorsal/lateral were retrospectively reviewed. Patients younger than 13 years of age at the time of operation and older than 14 years of age in November 2015 were included. Patients with a penile curvature of less than 30 degrees & more than 45 degrees and penile/urethral anomalies were excluded. All of the patients underwent surgery followed by circumcision. Results: The mean age of patients at the time of the operation was 9.7 years (range, 6-13 years. The mean degree of ventral penile curvature measured during the operation was 39 degrees while it was 41 degrees in the lateral curvatures. All of the patients were curvature-free at the end of the operation. At the time of the follow-up examination, the mean age was 16.7 years (range, 14-25 years. Six patients had a straight (0-10 degrees penis during erection and seven patients had recurrent penile curvatures ranging from 30 to 50 degrees. Conclusion: Pre pubertal tunica albuginea plication of congenital penile curvature (30-45 degrees with non-absorbable sutures performed without incision is a minimal invasive method especially when performed during circumcision. However, recurrence might be observed in half of the patients after puberty.

Positive, negative, and bipolar questions: The effect of question polarity on ratings of text readability

Directory of Open Access Journals (Sweden)

Naomi Kamoen

2013-12-01

Full Text Available For decades, survey researchers have known that respondents give different answers to attitude questions worded positively (X is good. Agree-Disagree, negatively (X is bad. Agree-Disagree or on a bipolar scale (X is bad-good. This makes survey answers hard to interpret, especially since findings on exactly how the answers are affected are conflicting. In the current paper, we present twelve studies in which the effect of question polarity was measured for a set of thirteen contrastive adjectives. In each study, the same adjectives were used so the generalizability of wording effects across studies could be examined for each word pair. Results show that for five of the word pairs an effect of question wording can be generalized. The direction of these effects are largely consistent: respondents generally give the same answers to positive and bipolar questions, but they are more likely to disagree with negative questions than to agree with positive questions or to choose the positive side of the bipolar scale. In other words, respondents express their opinions more positively when the question is worded negatively. Even though answers to the three wording alternatives sometimes differ, results also show that reliable answers can be obtained with all three wording alternatives. So, for survey practice, these results suggest that all three wording alternatives may be used for attitude measurement.

Human papillomavirus-associated cancers: A growing global problem

OpenAIRE

Bansal, Anshuma; Singh, Mini P; Rai, Bhavana

2016-01-01

Human papillomavirus (HPV) infection is linked with several cancers such as cancer cervix, vagina, vulva, head and neck, anal, and penile carcinomas. Although there is a proven association of HPV with these cancers, questions regarding HPV testing, vaccination, and treatment of HPV-related cancers continue to remain unanswered. The present article provides an overview of the HPV-associated cancers.

Expanding Boundaries: Current and New Directions in Study Abroad Research and Practice

Science.gov (United States)

Marijuan, Silvia; Sanz, Cristina

2018-01-01

In spite of advances in the understanding of the effects of the immersion experience on language and cultural development in the last three decades, many questions in study abroad (SA) research remain unanswered. The present article offers a close examination of the field as it is today with an eye toward future trends and gaps in the literature.…

Fostering Creativity for Leadership and Leading Change

Science.gov (United States)

Harding, Tayloe

2010-01-01

Creativity is about more than imagining or making something that has not previously existed. Though most of us perceive of the concept of creativity actualized as "creation", creativity is really much broader--it is that force in each of us that begins with a yearning to answer an unanswered (or ill-answered) question by imagining more than one…

Small animal positron emission tomography imaging and in vivo studies of atherosclerosis

DEFF Research Database (Denmark)

Hag, Anne Mette Fisker; Ripa, Rasmus Sejersten; Pedersen, Sune Folke

2013-01-01

Atherosclerosis is a growing health challenge globally, and despite our knowledge of the disease has increased over the last couple of decades, many unanswered questions remain. As molecular imaging can be used to visualize, characterize and measure biological processes at the molecular and cellu...... knowledge obtained from in vivo positron emission tomography studies of atherosclerosis performed in small animals....

Thousand Questions

DEFF Research Database (Denmark)

2012-01-01

(perhaps as an expanded Turing test) on its listeners. These questions are extracted in real-time from Twitter with the keyword search of the ‘?’ symbol to create a spatio-temporal experience. The computerized voice the audience hears is a collective one, an entanglement of humans and non-humans......In this work the network asks “If I wrote you a love letter would you write back?” Like the love letters which appeared mysteriously on the noticeboards of Manchester University’s Computer Department in the 1950s, thousands of texts circulate as computational processes perform the questions......, that circulates across networks. If I wrote you a love letter would you write back? (and thousands of other questions’ ) (封不回的情書？千言萬語無人回 was commissioned by the Microwave International New Media Festival 2012....

Setting research priorities in tobacco control: a stakeholder engagement project.

Science.gov (United States)

Lindson, Nicola; Richards-Doran, Dan; Heath, Laura; Hartmann-Boyce, Jamie

2017-12-01

The Cochrane Tobacco Addiction Group (TAG) conducts systematic reviews of the evidence for tobacco cessation and prevention interventions. In 2016 TAG conducted a priority-setting, stakeholder engagement project to identify where further research is needed in the areas of tobacco control and smoking cessation. The project comprised two surveys and a workshop. A range of stakeholders participated, including members of the public (smokers and ex-smokers), clinicians, researchers, research funders, health-care commissioners and public health organizations. The first survey phase identified unanswered research questions in the field of tobacco control. The second phase asked participants to rank these, with overall rankings calculated by combining scores across participants. The workshop allowed attendees to discuss prioritization of topics and questions in more depth. Workshop discussions were transcribed and analysed thematically, and a final voting activity at the close of the workshop allowed participants to choose topics to prioritize and to de-prioritize. A total of 304 stakeholders (researchers, health professionals, smokers and ex-smokers, guideline developers, research funders and policymakers, representing 28 countries) identified 183 unanswered research questions. These were categorized into 15 research categories. A total of 175 participants prioritized categories and questions in the second survey phase, with 'electronic cigarettes'; 'addressing inequalities'; and 'mental health and other substance abuse' prioritized as the top three categories. Forty-three stakeholders attended the workshop and discussed reasons for and against category prioritization. Prioritized research categories largely mirrored those in the survey stage, although 'treatment delivery' also emerged as a key category. Five cross-cutting themes emerged: efficacy; relative efficacy; cost effectiveness; addressing inequalities; and different types of evidence. There are many unanswered

Public worry and question about radiation hazard. Analysis of JHPS web-site opinion on Fukushima I accident

International Nuclear Information System (INIS)

Shimo, Michikuni

2011-01-01

This is a tentative interim report of worry and question appeared in Japan Health Physics Society (JHPS) web-site, which formally started from Mar. 25 in 2011 and had origins of voluntary activity by JHPS members from Mar. 16 and of subsequent Japan MECSST requirement on Mar. 18 concerning the Fukushima Daiichi Power Plant Accident (Fukushima I, Mar. 12). Replying to the health risk in the web essentially stood on the stance that the risk always exists, uncertainty is not unavoidable and risk concerns about public, not about individuals. Major two problems generated were solved by the answering with the manager name not with the responsible individual expert, and by the careful, detailed explanation (long sentence) about the safety dose standards. Questioners were thought mostly to be women of ages between 20 and 40 y. Their living addresses written were Tokyo, Chiba, Fukushima areas and so on, although they were mostly unwritten. The number of questions was 709 (10/day) until July 1; their major three items, when classified in 48, were related to the comparison with the nuclear explosion experiments, Chernobyl Accident and released nuclides from the Fukushima I; and their major key words contained were child (39 questions), health hazard and concern (25), food and water (16), etc. It has become clear that sufficient carefulness is necessary in telling non-experts who scarcely have the fundamental, systematic and mechanistic knowledge, about the assessment of the radiation health risk, where quantitativeness is highly important. The author hopes to publish answers not only as a documentary of the Accident but also as a system of concerned knowledge. (T.T.)

Future of mantle tomography and interface imaging: old questions, new challenges and opportunities

Science.gov (United States)

van der Hilst, R. D.

2011-12-01

Over the past three decades, tremendous progress has been made with the mapping of mantle heterogeneity and with the understanding of these structures in terms of, for instance, the evolution of Earth's crust, continental lithosphere, and thermo-chemical mantle convection. Converted wave imaging (e.g., receiver functions) and reflection seismology (e.g. SS stacks) have helped constrain interfaces in crust and mantle; surface wave dispersion (from earthquake or ambient noise signals) characterizes wavespeed variations in continental and oceanic lithosphere, and body wave and multi-mode surface wave data have been used to map trajectories of mantle convection and delineate mantle regions of anomalous elastic properties. Collectively, these studies have revealed substantial ocean-continent differences and suggest that convective flow is strongly influenced by but permitted to cross the upper mantle transition zone. Many questions have remained unanswered, however, and further advances in understanding require more accurate depictions of Earth's heterogeneity at a wider range of length scales. To meet this challenge we need new observations: more, better, and different types of data. Even without technological innovation, the use of new data will continue to produce spectacular results. Good examples are the positive impact on image quality of the seismograph arrays of the Australian Skippy project and USArray. At the same time, the huge volumes of (array) data and the desire to extract and interpret more signal from these data means that we have to abandon 'business as usual' (that is, simplified theory, manual inspection of seismograms, ...). Indeed, it inspires the development of automated full wave methods, both for tomographic delineation of smooth wavespeed variations and the imaging (for instance through inverse scattering) of medium contrasts. Adjoint tomography and reverse time migration, closely related wave equation methods, have begun to revolutionize

Legacy question

International Nuclear Information System (INIS)

Healy, J.W.

1977-01-01

The legacy question discussed refers to the definition of appropriate actions in this generation to provide a world that will allow future generations to use the earth without excessive limitations caused by our use and disposal of potentially hazardous materials

Production of Intonation Patterns of Non-English Major Student Teachers

Directory of Open Access Journals (Sweden)

Emily Luib-Beltran

2015-12-01

Full Text Available The study described the production of intonation pattern of the Non-English major student teachers during their on-campus teaching. The qualitative research method was used to analyze the data and describe their intonation patterns. The utterances were investigated in distinction between falling and rising intonation of wh-questions and yes/no questions. In the conduct of analysis, an interview guide was used to gather data on the language profile of the student teachers. Data confirm that the student teachers’ mother tongue (Filipino was commonly used in most of their verbal exchanges activities. It is worthy to note that the utterances of the student teachers displayed evidence of intonation patterns variation on wh-questions and yes/no questions. The erratic production of intonation patterns of the student teachers was resulted from the common linguistic phenomenon in which they tended to carry the intonation and pronunciation rules from their mother tongue (Filipino into their English spoken discourse. This qualitative research study implies that there is an interference of Filipino language in the production of the student teachers’ intonation patterns which describes the Philippine English intonation pattern for wh- questions and yes/no questions. Forthcoming studies may obtain more valued insights by gathering geographically varied samples that would include student teachers across disciplines.

An Online National Archive of Multiple-Choice Questions for Astro 101 and the Development of the Question Complexity Rubric

Science.gov (United States)

Cormier, S.; Prather, E.; Brissenden, G.

2011-09-01

We are developing a national archive of multiple-choice questions for use in the Astronomy 101 classroom. These questions are intended to supplement an instructor's implementation of Think-Pair-Share or for their assessment purposes (i.e., exams and homework). We are also developing the Question Complexity Rubric (QCR) to guide members of the Astro 101 teaching and learning community in assisting us with hierarchically ranking questions in this archive based on their conceptual complexity. Using the QCR, a score is assigned to differentiate each question based on the cognitive steps necessary to comprehensively explain the reasoning pathway to the correct answer. The lowest QCR score is given to questions with a reasoning pathway requiring only declarative knowledge. The highest QCR score is given to questions with a reasoning pathway that requires multiple connected cognitive steps. When completed, the online question archive will provide users with the utility to 1) use the QCR to score questions 2) search for and download questions based on topic and/or QCR score, and 3) add their own questions to the archive. Stop by our poster to test your skills at determining question complexity by trying out the QCR with our sample questions.

Difficult Questions of Difficult Questions: The Role of The Researcher and Transcription Styles

Science.gov (United States)

Henderson, Holly

2018-01-01

This paper refracts a comparison of three distinct transcription styles through questions of researcher reflexivity. It uses the data from a single question asked by the researcher in multiple interviews for a small empirical project. These data are transcribed in three ways, and the resulting transcripts are discussed in relation to the analysis…

Threat, Fear, and Persuasion: Review and Critique of Questions About Functional Form

Directory of Open Access Journals (Sweden)

Lijiang Shen

2014-01-01

Full Text Available Theories of threat appeals have been rightly concerned with the form of the relationship between fear and persuasion: Linear or curvilinear. They have not, however, clearly distinguished the question as a between- or within-persons phenomenon. In fact, the literature often treats these two perspectives as if they were interchangeable. We show that between- versus within-person questions about functional form are distinct from one another. Previous research, which is the product of between-persons designs, shows a linear relationship between fear and persuasion. Betweenpersons studies cannot address the question of how changes in fear over time produce persuasion. Consequently, a major piece of the fear appeals-persuasion puzzle may have been overlooked. Reanalysis of an existing data set shows curvilinearity of fear in within-persons data and demonstrates that the curve predicts persuasion. Audience segmentation reveals different curves for different groups as well as differential associations between those curves and persuasion. Overall, the argument and the empirical results suggest that a great deal less is known about fear appeals than it is currently believed.

The Impact of New Major Offerings on Student Retention

Science.gov (United States)

Sauer, Paul L.; O'Donnell, Joseph B.

2006-01-01

A strategy used by industry to retain customers and remain competitive is the design and launch of new products. One might then question whether the launch of new courses and new majors by colleges and universities has the potential of reducing student attrition. Combining survey data from matriculating freshmen with administrative data taken from…

Recent advances in food allergy

Directory of Open Access Journals (Sweden)

Marcos Julio Caruso Alcocer

Full Text Available Summary Food allergy is a public health issue that has significantly increased worldwide in the past decade, affecting consumers’ quality of life and making increasing demands on health service resources. Despite recent advances in many areas of diagnosis and treatment, our general knowledge of the basic mechanisms of the disease remain limited i.e., not at pace with the exponential number of new cases and the explosion of new technologies. Many important key questions remain: What defines a major allergen? Why do some individuals develop food allergies and others do not? Which are the environmental factors? Could the environmental factors be monitored through epigenetics or modified by changes in the microbiome? Can tolerance to food be induced? Why are some foods more likely to trigger allergies than others? Does the route and timing of exposure have any role on sensitization? These and many other related questions remain unanswered. In this short review some of these topics are addressed in the light of recent advances in the area.

malERA: An updated research agenda for basic science and enabling technologies in malaria elimination and eradication

Science.gov (United States)

2017-01-01

Basic science holds enormous power for revealing the biological mechanisms of disease and, in turn, paving the way toward new, effective interventions. Recognizing this power, the 2011 Research Agenda for Malaria Eradication included key priorities in fundamental research that, if attained, could help accelerate progress toward disease elimination and eradication. The Malaria Eradication Research Agenda (malERA) Consultative Panel on Basic Science and Enabling Technologies reviewed the progress, continuing challenges, and major opportunities for future research. The recommendations come from a literature of published and unpublished materials and the deliberations of the malERA Refresh Consultative Panel. These areas span multiple aspects of the Plasmodium life cycle in both the human host and the Anopheles vector and include critical, unanswered questions about parasite transmission, human infection in the liver, asexual-stage biology, and malaria persistence. We believe an integrated approach encompassing human immunology, parasitology, and entomology, and harnessing new and emerging biomedical technologies offers the best path toward addressing these questions and, ultimately, lowering the worldwide burden of malaria. PMID:29190277

Everything You Always Wanted to Know About Rabies Virus (But Were Afraid to Ask).

Science.gov (United States)

Davis, Benjamin M; Rall, Glenn F; Schnell, Matthias J

2015-11-01

The cultural impact of rabies, the fatal neurological disease caused by infection with rabies virus, registers throughout recorded history. Although rabies has been the subject of large-scale public health interventions, chiefly through vaccination efforts, the disease continues to take the lives of about 40,000-70,000 people per year, roughly 40% of whom are children. Most of these deaths occur in resource-poor countries, where lack of infrastructure prevents timely reporting and postexposure prophylaxis and the ubiquity of domestic and wild animal hosts makes eradication unlikely. Moreover, although the disease is rarer than other human infections such as influenza, the prognosis following a bite from a rabid animal is poor: There is currently no effective treatment that will save the life of a symptomatic rabies patient. This review focuses on the major unanswered research questions related to rabies virus pathogenesis, especially those connecting the disease progression of rabies with the complex dysfunction caused by the virus in infected cells. The recent applications of cutting-edge research strategies to this question are described in detail.

Do we track what we see? Common versus independent processing for motion perception and smooth pursuit eye movements: a review.

Science.gov (United States)

Spering, Miriam; Montagnini, Anna

2011-04-22

Many neurophysiological studies in monkeys have indicated that visual motion information for the guidance of perception and smooth pursuit eye movements is - at an early stage - processed in the same visual pathway in the brain, crucially involving the middle temporal area (MT). However, these studies left some questions unanswered: Are perception and pursuit driven by the same or independent neuronal signals within this pathway? Are the perceptual interpretation of visual motion information and the motor response to visual signals limited by the same source of neuronal noise? Here, we review psychophysical studies that were motivated by these questions and compared perception and pursuit behaviorally in healthy human observers. We further review studies that focused on the interaction between perception and pursuit. The majority of results point to similarities between perception and pursuit, but dissociations were also reported. We discuss recent developments in this research area and conclude with suggestions for common and separate principles for the guidance of perceptual and motor responses to visual motion information. Copyright © 2010 Elsevier Ltd. All rights reserved.

Stress and Cognition: A Cognitive Psychological Perspective

Science.gov (United States)

Bourne, Lyle E., Jr.; Yaroush, Rita A.

2003-01-01

Research in cognitive psychology has made a significant contribution to our understanding of how acute and chronic stress affect performance. It has done so by identifying some of the factors that contribute to operator error and by suggesting how operators might be trained to respond more effectively in a variety of circumstances. The major purpose of this paper was to review the literature of cognitive psychology as it relates to these questions and issues. Based on the existence of earlier reviews (e.g., Hamilton, & Warburton, 1979; Hockey, 1983) the following investigation was limited to the last 15 years (1988-2002) and restricted to a review of the primary peer-reviewed literature. The results of this examination revealed that while cognitive psychology has contributed in a substantive way to our understanding of stress impact on various cognitive processes, it has also left many questions unanswered. Concerns about how we define and use the term stress and the gaps that remain in our knowledge about the specific effects of stressors on cognitive processes are discussed in the text.

Let's talk nuclear energy in 30 questions; Parlons nucleaire en 30 questions

Energy Technology Data Exchange (ETDEWEB)

Reuss, Paul

2012-01-11

The Fukushima catastrophe of March 11, 2011 has called into question the share of nuclear energy in France and in foreign countries. Its replacement by renewable energy sources and the safety of nuclear power plants are in the center of today's debates. But what is the reality behind the mass of contradictory information that exists on this complex topic? This book moves the question out of the media noise and supplies objective and factual information with reliable figures about the nuclear industry by answering 30 key-questions. (J.S.)

Question, answer, compare: a cross-category comparison of answers on question and answer websites

Science.gov (United States)

Ocepek, Melissa G.; Westbrook, Lynn

2015-10-01

Online information seekers make heavy use of websites that accept their natural language questions. This study compared the three types of such websites: social question and answer (Q&A), digital reference services, and ask-an-expert services. Questions reflecting daily life, research, and crisis situations were posed to high use websites of all three types. The resulting answers' characteristics were analyzed in terms of speed, transparency, formality, and intimacy. The results indicate that social Q&A websites excel in speed, ask-an-expert websites in intimacy, and digital reference services in transparency and formality.

Examining the Impact of Question Surface Features on Students' Answers to Constructed-Response Questions on Photosynthesis

Science.gov (United States)

Weston, Michele; Haudek, Kevin C.; Prevost, Luanna; Urban-Lurain, Mark; Merrill, John

2015-01-01

One challenge in science education assessment is that students often focus on surface features of questions rather than the underlying scientific principles. We investigated how student written responses to constructed-response questions about photosynthesis vary based on two surface features of the question: the species of plant and the order of…

Generic Drugs: Questions and Answers

Science.gov (United States)

... Vaccines, Blood & Biologics Animal & Veterinary Cosmetics Tobacco Products Drugs Home Drugs Resources for You Information for Consumers (Drugs) Questions & Answers Generic Drugs: Questions & Answers Share Tweet Linkedin Pin it More ...

Introduction to the Major Contribution: Counseling Psychology and Online Counseling

Science.gov (United States)

Mallen, Michael J.; Vogel, David L.

2005-01-01

This article introduces the Major Contribution, which focuses on online counseling. Several acronyms and terms are presented to familiarize the reader with distance-communication technology, including a definition of online counseling. The authors show how counseling psychology provides a framework for specific questions related to the theory,…

Organic Chemistry Trivia: A Way to Interest Nonchemistry Majors

Science.gov (United States)

Farmer, Steven C.

2011-01-01

The use of in-class stories is an excellent way to keep a class interested in subject matter. Many organic chemistry classes are populated by nonchemistry majors, such as pre-med, pre-pharm, and biology students. Trivia questions are presented that are designed to show how organic chemistry is an important subject to students regardless of their…

Comparison of Performance on Multiple-Choice Questions and Open-Ended Questions in an Introductory Astronomy Laboratory

Science.gov (United States)

Wooten, Michelle M.; Cool, Adrienne M.; Prather, Edward E.; Tanner, Kimberly D.

2014-01-01

When considering the variety of questions that can be used to measure students' learning, instructors may choose to use multiple-choice questions, which are easier to score than responses to open-ended questions. However, by design, analyses of multiple-choice responses cannot describe all of students' understanding. One method that can…

Questioning context: a set of interdisciplinary questions for investigating contextual factors affecting health decision making

Science.gov (United States)

Charise, Andrea; Witteman, Holly; Whyte, Sarah; Sutton, Erica J.; Bender, Jacqueline L.; Massimi, Michael; Stephens, Lindsay; Evans, Joshua; Logie, Carmen; Mirza, Raza M.; Elf, Marie

2011-01-01

Abstract Objective  To combine insights from multiple disciplines into a set of questions that can be used to investigate contextual factors affecting health decision making. Background  Decision‐making processes and outcomes may be shaped by a range of non‐medical or ‘contextual’ factors particular to an individual including social, economic, political, geographical and institutional conditions. Research concerning contextual factors occurs across many disciplines and theoretical domains, but few conceptual tools have attempted to integrate and translate this wide‐ranging research for health decision‐making purposes. Methods  To formulate this tool we employed an iterative, collaborative process of scenario development and question generation. Five hypothetical health decision‐making scenarios (preventative, screening, curative, supportive and palliative) were developed and used to generate a set of exploratory questions that aim to highlight potential contextual factors across a range of health decisions. Findings  We present an exploratory tool consisting of questions organized into four thematic domains – Bodies, Technologies, Place and Work (BTPW) – articulating wide‐ranging contextual factors relevant to health decision making. The BTPW tool encompasses health‐related scholarship and research from a range of disciplines pertinent to health decision making, and identifies concrete points of intersection between its four thematic domains. Examples of the practical application of the questions are also provided. Conclusions  These exploratory questions provide an interdisciplinary toolkit for identifying the complex contextual factors affecting decision making. The set of questions comprised by the BTPW tool may be applied wholly or partially in the context of clinical practice, policy development and health‐related research. PMID:21029277

Developing Independence in a Capstone Course: Helping Students Ask and Answer Their Own Questions

Science.gov (United States)

Camenga, Kristin A.

2013-01-01

We discuss a mathematics capstone course designed to help students grow in mathematical independence. We describe how the course is structured to support this goal and the major assignments: a course wiki, a group expository project, and an individual problem to solve and extend. Students learn to ask and answer their own questions, helping them…

Adult Neurogenesis in the Mammalian Brain: Significant Answers and Significant Questions

Science.gov (United States)

Ming, Guo-li; Song, Hongjun

2011-01-01

Summary Adult neurogenesis, a process of generating functional neurons from adult neural precursors, occurs throughout life in restricted brain regions in mammals. The past decade has witnessed tremendous progress in addressing questions related to almost every aspect of adult neurogenesis in the mammalian brain. Here we review major advances in our understanding of adult mammalian neurogenesis in the dentate gyrus of the hippocampus and from the subventricular zone of the lateral ventricle, the rostral migratory stream to the olfactory bulb. We highlight emerging principles that have significant implications for stem cell biology, developmental neurobiology, neural plasticity, and disease mechanisms. We also discuss remaining questions related to adult neural stem cells and their niches, underlying regulatory mechanisms and potential functions of newborn neurons in the adult brain. Building upon the recent progress and aided by new technologies, the adult neurogenesis field is poised to leap forward in the next decade. PMID:21609825

Annotating Logical Forms for EHR Questions.

Science.gov (United States)

Roberts, Kirk; Demner-Fushman, Dina

2016-05-01

This paper discusses the creation of a semantically annotated corpus of questions about patient data in electronic health records (EHRs). The goal is to provide the training data necessary for semantic parsers to automatically convert EHR questions into a structured query. A layered annotation strategy is used which mirrors a typical natural language processing (NLP) pipeline. First, questions are syntactically analyzed to identify multi-part questions. Second, medical concepts are recognized and normalized to a clinical ontology. Finally, logical forms are created using a lambda calculus representation. We use a corpus of 446 questions asking for patient-specific information. From these, 468 specific questions are found containing 259 unique medical concepts and requiring 53 unique predicates to represent the logical forms. We further present detailed characteristics of the corpus, including inter-annotator agreement results, and describe the challenges automatic NLP systems will face on this task.

Generating ethnographic research questions

DEFF Research Database (Denmark)

Friberg, Torbjörn

2015-01-01

? By drawing on the conceptual history of anthropology, the aim of this article is to generate ethnographic-oriented research questions concerned with higher education. The first part of the article provides an ethnographic background, while the second part focuses on Paul Willis's reasoning on ethnographic......As part of recent complex transformations, it seems that higher educational organisations are being forced to reorganise, standardise and streamline in order to survive in the new political and economic context. How are ethnographers in general going to approach these contemporary phenomena...... imagination, as a prerequisite for generating alternative research questions. The third part makes explicit anthropologist Maurice Godelier's theoretical imagination, carving out some specific theoretical parts which may be used in the generating process. The conclusion then suggests a number of questions...

Major Thought Restructuring: The Roles of Different Prefrontal Cortical Regions.

Science.gov (United States)

Seyed-Allaei, Shima; Avanaki, Zahra Nasiri; Bahrami, Bahador; Shallice, Tim

2017-07-01

An important question for understanding the neural basis of problem solving is whether the regions of human prefrontal cortices play qualitatively different roles in the major cognitive restructuring required to solve difficult problems. However, investigating this question using neuroimaging faces a major dilemma: either the problems do not require major cognitive restructuring, or if they do, the restructuring typically happens once, rendering repeated measurements of the critical mental process impossible. To circumvent these problems, young adult participants were challenged with a one-dimensional Subtraction (or Nim) problem [Bouton, C. L. Nim, a game with a complete mathematical theory. The Annals of Mathematics, 3, 35-39, 1901] that can be tackled using two possible strategies. One, often used initially, is effortful, slow, and error-prone, whereas the abstract solution, once achieved, is easier, quicker, and more accurate. Behaviorally, success was strongly correlated with sex. Using voxel-based morphometry analysis controlling for sex, we found that participants who found the more abstract strategy (i.e., Solvers) had more gray matter volume in the anterior medial, ventrolateral prefrontal, and parietal cortices compared with those who never switched from the initial effortful strategy (i.e., Explorers). Removing the sex covariate showed higher gray matter volume in Solvers (vs. Explorers) in the right ventrolateral prefrontal and left parietal cortex.

Instance-Based Question Answering

Science.gov (United States)

2006-12-01

cluster-based query expan- sion, learning answering strategies, machine learning in NLP To my wife Monica Abstract During recent years, question...process is typically tedious and involves expertise in crafting and implement- ing these models (e.g. rule-based), utilizing NLP resources, and...questions. For languages that use capitalization (e.g. not Chinese or Arabic ) for named entities, IBQA can make use of NE classing (e.g. “Bob Marley

Protein Electrochemistry: Questions and Answers.

Science.gov (United States)

Fourmond, V; Léger, C

This chapter presents the fundamentals of electrochemistry in the context of protein electrochemistry. We discuss redox proteins and enzymes that are not photoactive. Of course, the principles described herein also apply to photobioelectrochemistry, as discussed in later chapters of this book. Depending on which experiment is considered, electron transfer between proteins and electrodes can be either direct or mediated, and achieved in a variety of configurations: with the protein and/or the mediator free to diffuse in solution, immobilized in a thick, hydrated film, or adsorbed as a sub-monolayer on the electrode. The experiments can be performed with the goal to study the protein or to use it. Here emphasis is on mechanistic studies, which are easier in the configuration where the protein is adsorbed and electron transfer is direct, but we also explain the interpretation of signals obtained when diffusion processes affect the response.This chapter is organized as a series of responses to questions. Questions 1-5 are related to the basics of electrochemistry: what does "potential" or "current" mean, what does an electrochemical set-up look like? Questions 6-9 are related to the distinction between adsorbed and diffusive redox species. The answers to questions 10-13 explain the interpretation of slow and fast scan voltammetry with redox proteins. Questions 14-19 deal with catalytic electrochemistry, when the protein studied is actually an enzyme. Questions 20, 21 and 22 are general.

IMS Learning Design Frequently Asked Questions

NARCIS (Netherlands)

Tattersall, Colin; Manderveld, Jocelyn; Hummel, Hans; Sloep, Peter; Koper, Rob; De Vries, Fred

2004-01-01

This list of frequently asked questions was composed on the basis of questions asked of the Educational Technology Expertise Centrum. The questions addessed are: Where can I find the IMS Learning Design Specification? What is meant by the phrase “Learning Design”? What is the IMS LD Specification

Initiation and propagation of neurodegeneration.

Science.gov (United States)

Haass, Christian

2010-11-01

Although substantial progress has been made in understanding the molecular and pathological bases of neurodegeneration, there have been few successes in the clinic and a number of fundamental questions remain unanswered. Is this skepticism misplaced, or do the words of Sir Isaac Newton hold true, that "what we know is a drop, what we don't know is an ocean"?

Questioning As a Pedagogical Tool for Eliciting Student Generated Questions During the Teaching of Acid-base Equilibria

Directory of Open Access Journals (Sweden)

Ayoade Ejiwale Okanlawon

2012-04-01

Full Text Available Traditionally, teachers simply taught problem-solving by explaining the worked-out examples taken from textbooks and students were expected to listen quietly, copy the solution to the problem, and then work independently at their desks. But a large body of research notes that guiding students to develop a solution pathway with questioning is more effective than simply explaining the sequence of steps to solve the problem. Students involved in question- and-answer sessions are more attentive than those who listen passively to teacher explanations and they are more likely to generate questions. The questions students ask during a lesson perform a number of important functions, including providing the teacher with valuable information about students’ understanding and misunderstanding, fostering self-regulation, inviting classroom discussions and aiding comprehension of contents presented. The skill of posing questions during classroom instruction is often under-valued and under taught in today’s classrooms. To encourage students to ask quality and thought provoking questions related to the contents taught, explicit instruction is required. This paper, therefore, qualitatively reports factors that foster student generated questions during the problem-solving instruction involving acid-base titration problem.

Major advances associated with hormone and growth factor regulation of mammary growth and lactation in dairy cows.

Science.gov (United States)

Akers, R M

2006-04-01

In recent years, the number of researchers interested in mammary development and mammary function in dairy animals has declined. More importantly this cadre of workers has come to rely more than ever on scientists focused on and funded by breast cancer interests to provide fundamental mechanistic and basic cellular insights. Philosophically and practically this is a risky path to better understand, manipulate, and control a national resource as important as the dairy cow. The efficiency, resourcefulness, and dedication of dairy scientists have mirrored the actions of many dairy producers but there are limits. Many of the applications of research, use of bovine somatotropin, management of transition cows, estrus synchronization techniques, and so on, are based on decades-old scientific principles. Specific to dairy, do rodents or breast cancer cell lines adequately represent the dairy cow? Will these results inspire the next series of lactation-related dairy improvements? These are key unanswered questions. Study of the classic mammogenic and lactogenic hormones has served dairy scientists well. But there is an exciting, and bewildering universe of growth factors, transcription factors, receptors, intracellular signaling intermediates, and extracellular molecules that must ultimately interact to determine the size of the mature udder and the functional capacity of mammary gland in the lactating cow. We can only hope that enough scientific, fiscal, and resource scraps fall from the biomedical research banquet table to allow dairy-focused mammary gland research to continue.

We be jammin’: an update on pectin biosynthesis, trafficking and dynamics

Energy Technology Data Exchange (ETDEWEB)

Anderson, Charles T.

2015-11-20

Pectins are complex polysaccharides that contain acidic sugars and are major determinants of the cohesion, adhesion, extensibility, porosity and electrostatic potential of plant cell walls. Recent evidence has solidified their positions as key regulators of cellular growth and tissue morphogenesis, although important details of how they achieve this regulation are still missing. Pectins are also hypothesized to function as ligands for wall integrity sensors that enable plant cells to respond to intrinsic defects in wall biomechanics and to wall degradation by attacking pathogens. This update highlights recent advances in our understanding of the biosynthesis of pectins, how they are delivered to the cell surface and become incorporated into the cell wall matrix and how pectins are modified over time in the apoplast. It also poses unanswered questions for further research into this enigmatic but essential class of carbohydrate polymers.

The Interplay of Top-Down and Bottom-Up

DEFF Research Database (Denmark)

Winkler, Till; Brown, Carol V.; Ozturk, Pinar

2014-01-01

The exchange of patient health information across different organizations involved in healthcare delivery has potential benefits for a wide range of stakeholders. However, many governments in Europe and in the U.S. have, despite both top-down and bottom-up initiatives, experienced major barriers...... in achieving sustainable models for implementing health information exchange (HIE) throughout their healthcare systems. In the case of the U.S., three years after stimulus funding allocated as part of the 2009 HITECH Act, the extent to which government funding will be needed to sustain health information...... organizations (HIOs) that facilitate HIE across regional stakeholders remains an unanswered question. This research investigates the impacts of top-down and bottom-up initiatives on the evolutionary paths of HIOs in two contingent states in the U.S. (New Jersey and New York) which had different starting...

The ALTA cosmic ray experiment electronics system

International Nuclear Information System (INIS)

Brouwer, W.; Burris, W.J.; Caron, B.; Hewlett, J.; Holm, L.; Hamilton, A.; McDonald, W.J.; Pinfold, J.L.; Price, P.; Schaapman, J.R.; Sibley, L.; Soluk, R.A.; Wampler, L.J.

2005-01-01

Understanding the origin and propagation of high-energy cosmic rays is a fundamental area of astroparticle physics with major unanswered questions. The study of cosmic rays with energy more than 10 14 eV, probed only by ground-based experiments, has been restricted by the low particle flux. The Alberta Large-area Time-coincidence Array (ALTA) uses a sparse array of cosmic ray detection stations located in high schools across a large geographical area to search for non-random high-energy cosmic ray phenomena. Custom-built ALTA electronics is based on a modular board design. Its function is to control the detectors at each ALTA site allowing precise measurements of event timing and energy in the local detectors as well as time synchronization of all of the sites in the array using the global positioning system

From Ethanol to Salsolinol: Role of Ethanol Metabolites in the Effects of Ethanol

Directory of Open Access Journals (Sweden)

Alessandra T. Peana

2016-01-01

Full Text Available In spite of the global reputation of ethanol as the psychopharmacologically active ingredient of alcoholic drinks, the neurobiological basis of the central effects of ethanol still presents some dark sides due to a number of unanswered questions related to both its precise mechanism of action and its metabolism. Accordingly, ethanol represents the interesting example of a compound whose actions cannot be explained as simply due to the involvement of a single receptor/neurotransmitter, a scenario further complicated by the robust evidence that two main metabolites, acetaldehyde and salsolinol, exert many effects similar to those of their parent compound. The present review recapitulates, in a perspective manner, the major and most recent advances that in the last decades boosted a significant growth in the understanding on the role of ethanol metabolism, in particular, in the neurobiological basis of its central effects.

If reform of science education is the answer - what were the questions?

DEFF Research Database (Denmark)

2003-01-01

questions remain open: What is the aim of modern natural science education? How can the teaching methods and curriculum structure best support all this? How are changes of teaching practices best initiated? How does the university teacher improve his or her own teaching? These questions were addressed......At most Danish universities dramatic changes of the natural science programmes are under way. These changes are carried out both in response to external forces, and to internal ones, such as the need to rethink curriculum and pedagogy. But while the answer - structural reforms - is clear, the major...... at the third May Conference of the Centre for Educational Development in University Science (Dansk Center for Naturvidenskabsdidaktik, DCN), 22 -23 May, 2003, in Korsør, Denmark. This publication contains presentations given at the conference by keynote speakers. Further, it includes extensive reports from...

Predicting How Nanoconfinement Changes the Relaxation Time of a Supercooled Liquid

DEFF Research Database (Denmark)

Ingebrigtsen, Trond; Errington, Jeff; Truskett, Tom

2013-01-01

The properties of nanoconfined fluids can be strikingly different from those of bulk liquids. A basic unanswered question is whether the equilibrium and dynamic consequences of confinement are related to each other in a simple way. We study this question by simulation of a liquid comprising...... asymmetric dumbbell-shaped molecules, which can be deeply supercooled without crystallizing. We find that the dimensionless structural relaxation times—spanning six decades as a function of temperature, density, and degree of confinement—collapse when plotted versus excess entropy. The data also collapse...

Managing missing scores on the Roland Morris Disability Questionnaire

DEFF Research Database (Denmark)

Kent, Peter; Lauridsen, Henrik Hein

2011-01-01

Study Design: Analysis of Roland Morris Disability Questionnaire (RMDQ) and Oswestry Disability Index (Oswestry) responses.Objectives: To determine the prevalence of unanswered questions on the RMDQ23 (23-item RMDQ version) and Oswestry questionnaires. To determine if managing RMDQ23 missing data...... fully completed RMDQ23 and matching Oswestry questionnaire sets. Raw sum scores were calculated, and questions systematically dropped. At each stage, sum scores were converted to a score on a 0-100 scale and the error calculated. Wilcoxon Tests were used to compare the magnitude of the error scores...

Uncovering the genetic history of the present-day greenlandic population

DEFF Research Database (Denmark)

Moltke, Ida; Fumagalli, Matteo; Korneliussen, Thorfinn Sand

2015-01-01

Because of past limitations in samples and genotyping technologies, important questions about the history of the present-day Greenlandic population remain unanswered. In an effort to answer these questions and in general investigate the genetic history of the Greenlandic population, we analyzed...... between the Norse Vikings who lived in Greenland for a limited period ∼600-1,000 years ago and the Inuit, we found no evidence supporting this hypothesis. Similarly, we found no evidence supporting a previously hypothesized admixture event between the Inuit in East Greenland and the Dorset people, who...

How social networks influence female students' choices to major in engineering

Science.gov (United States)

Weinland, Kathryn Ann

Scope and Method of Study: This study examined how social influence plays a part in female students' choices of college major, specifically engineering instead of science, technology, and math. Social influence may show itself through peers, family members, and teachers and may encompass resources under the umbrella of social capital. The purpose of this study was to examine how female students' social networks, through the lens of social capital, influence her major choice of whether or not to study engineering. The variables of peer influence, parental influence, teacher/counselor influence, perception of engineering, and academic background were addressed in a 52 question, Likert scale survey. This survey has been modified from an instrument previously used by Reyer (2007) at Bradley University. Data collection was completed using the Dillman (2009) tailored design model. Responses were grouped into four main scales of the dependent variables of social influence, encouragement, perceptions of engineering and career motivation. A factor analysis was completed on the four factors as a whole, and individual questions were not be analyzed. Findings and Conclusions: This study addressed the differences in social network support for female freshmen majoring in engineering versus female freshmen majoring in science, technology, or math. Social network support, when working together from all angles of peers, teachers, parents, and teachers/counselors, transforms itself into a new force that is more powerful than the summation of the individual parts. Math and science preparation also contributed to female freshmen choosing to major in engineering instead of choosing to major in science, technology, or math. The STEM pipeline is still weak and ways in which to reinforce it should be examined. Social network support is crucial for female freshmen who are majoring in science, technology, engineering, and math.

The Question Concerning Thinking

DEFF Research Database (Denmark)

Riis, Søren

2008-01-01

Martin Heidegger's thought-provoking essay "The Question Concerning Technology" (1977a) placed technology at the heart of philosophy. Heidegger tried to show that the essence of technology provokes humans to think about the world in a very dangerous way. Yet if we follow Heidegger's analysis...... of technology, what role does that ascribe to philosophy? To be able to understand the programmatic scope of Heidegger's question ‘concerning' technology, we need to see it as inseparable from his famous thesis about the end of philosophy (1977c) and what he considers to be the ideal kind of thinking. However......, by doing so, we will in the end realize two important things. First, that Heidegger's declaration of the end of philosophy in fact also means the end of anything we can meaningfully call thinking. Second, that Heidegger's own thinking is completely different from his own ideal of thinking. Our question...

Comparison of performance on multiple-choice questions and open-ended questions in an introductory astronomy laboratory

OpenAIRE

Michelle M. Wooten; Adrienne M. Cool; Edward E. Prather; Kimberly D. Tanner

2014-01-01

When considering the variety of questions that can be used to measure students’ learning, instructors may choose to use multiple-choice questions, which are easier to score than responses to open-ended questions. However, by design, analyses of multiple-choice responses cannot describe all of students’ understanding. One method that can be used to learn more about students’ learning is the analysis of the open-ended responses students’ provide when explaining their multiple-choice response. I...

Beyond Astro 101: A First Report on Applying Interactive Education Techniques to an Astronphysics Class for Majors

Science.gov (United States)

Perrin, Marshall D.; Ghez, A. M.

2009-05-01

Learner-centered interactive instruction methods now have a proven track record in improving learning in "Astro 101" courses for non-majors, but have rarely been applied to higher-level astronomy courses. Can we hope for similar gains in classes aimed at astrophysics majors, or is the subject matter too fundamentally different for those techniques to apply? We present here an initial report on an updated calculus-based Introduction to Astrophysics class at UCLA that suggests such techniques can indeed result in increased learning for major students. We augmented the traditional blackboard-derivation lectures and challenging weekly problem sets by adding online questions on pre-reading assignments (''just-in-time teaching'') and frequent multiple-choice questions in class ("Think-Pair-Share''). We describe our approach, and present examples of the new Think-Pair-Share questions developed for this more sophisticated material. Our informal observations after one term are that with this approach, students are more engaged and alert, and score higher on exams than typical in previous years. This is anecdotal evidence, not hard data yet, and there is clearly a vast amount of work to be done in this area. But our first impressions strongly encourage us that interactive methods should be able improve the astrophysics major just as they have improved Astro 101.

Purified Timothy grass pollen major allergen Phl p 1 may contribute to the modulation of allergic responses through a pleiotropic induction of cytokines and chemokines from airway epithelial cells.

NARCIS (Netherlands)

Röschmann, K.I.L.; van Kuijen, A.M.; Luiten, S.; Jonker, M.J.; Breit, T.M.; Fokkens, W.J.; Petersen, A.; van Drunen, C.M.

2012-01-01

By definition, allergens are proteins with the ability to elicit powerful T helper lymphocyte type 2 (Th2) responses, culminating in immunoglobulin (Ig)E antibody production. Why specific proteins cause aberrant immune responses has remained largely unanswered. Recent data suggest that there may be

Purified Timothy grass pollen major allergen Phl p 1 may contribute to the modulation of allergic responses through a pleiotropic induction of cytokines and chemokines from airway epithelial cells

NARCIS (Netherlands)

Röschmann, K. I. L.; van Kuijen, A.-M.; Luiten, S.; Jonker, M. J.; Breit, T. M.; Fokkens, W. J.; Petersen, A.; van Drunen, C. M.

2012-01-01

By definition, allergens are proteins with the ability to elicit powerful T helper lymphocyte type 2 (Th2) responses, culminating in immunoglobulin (Ig)E antibody production. Why specific proteins cause aberrant immune responses has remained largely unanswered. Recent data suggest that there may be

Questioning the Patient, Questioning Hippocrates: Rufus of Ephesus and the Pursuit of Knowledge.

Science.gov (United States)

Letts, Melinda

2016-01-01

Rufus of Ephesus' short treatise, Quaestiones Medicinales, the only ancient medical work that takes as its topic the dialogue between doctor and patient, has usually been seen as a procedural practical handbook serving an essentially operational purpose. In this paper I argue that the treatise, with its insistent message that doctors cannot properly understand and treat illnesses unless they supplement their own knowledge by questioning patients, and its remarkable appreciation of the singularity of each patient's experience, shows itself to be no mere handbook but a work addressing the place of questioning in the clinical encounter. I illustrate some of the differences between Rufus' conceptualisation of the relevance and use of questioning and that which can be seen in the theoretical and descriptive writings of Galen and in the Hippocratic corpus, and show how apparent resonances with some of the preoccupations of modern Western healthcare can be used judiciously to elucidate the significance of those differences.

Multiple primary malignancies of the liver and the colon: a complex diagnostic and decisional process with a final unanswered question.

Science.gov (United States)

Portolani, Nazario; Baiocchi, Gianluca; Baronchelli, Carla; Gheza, Federico; Giulini, Stefano Maria

2014-03-29

We herein present the case of a 78-year-old man with an incidental finding of a solid hepatic mass without symptoms and only a laparotomic cholecystectomy for acute cholecystitis in the past surgical history. A colonoscopy, a magnetic resonance imaging scan, a positron emission tomography scan, and a computed tomography scan completed the preoperative workup: a neoplastic lesion 4.3×3 cm in size was diagnosed at segments IV and V, associated with a neoplastic involvement of the splenic flexure without signs of colonic occlusion. After colonic resection, a frozen section on a granulomatous-like tissue at gastric border suggested a diagnosis of an adenocarcinoma of bilio-pancreatic type, changing the surgical strategy to include gastric resection and hepatic pedicle node dissection. The discussion turns around the idea that a final diagnosis of colon cancer with regional nodal involvement (pT3N1) and metastatic gallbladder cancer with multiple peritoneal seedings cannot be excluded.

50 years of nuclear fission

International Nuclear Information System (INIS)

Hilscher, D.

1989-01-01

The article tells the story of the discovery of nuclear fission in Berlin 50 years ago by Otto Hahn and Fritz Strassmann in cooperation with Lise Meitner. 50 years later nuclear fission is still a subject of research. Some question remain unanswered. Selected new research results are used to discuss the dynamics of the collective movement of the elementary nuclear fission process. (orig.) [de

The neural bases of cognitive processes in gambling disorder

OpenAIRE

Potenza, Marc N.

2014-01-01

Functional imaging is offering powerful new tools to investigate the neurobiology of cognitive functioning in people with and without psychiatric conditions like gambling disorder. Based on similarities between gambling and substance-use disorders in neurocognitive and other domains, gambling disorder has recently been classified in DSM-5 as a behavioral addiction. Despite the advances in understanding, there exist multiple unanswered questions about the pathophysiology underlying gambling di...

Biogeography of Iberian freshwater fishes revisited: The roles of historical versus contemporary constraints

Science.gov (United States)

Filipe, Ana F.; Araújo, Miguel B.; Doadrio, Ignacio; Angermeier, Paul L.; Collares-Pereira, Maria J.

2009-01-01

Aim The question of how much of the shared geographical distribution of biota is due to environmental vs. historical constraints remains unanswered. The aim of this paper is to disentangle the contribution of historical vs. contemporary factors to the distribution of freshwater fish species. In addition, it illustrates how quantifying the contribution of each type of factor improves the classification of biogeographical provinces.

Medical professionalism: a tale of two doctors.

Science.gov (United States)

Gorrindo, Tristan; Groves, James E

2011-01-01

The AMA's social media guidelines provide physicians with some basic rules for maintaining professional boundaries when engaging in online activities. Left unanswered are questions about how these guidelines are to be implemented by physicians of different generations. By examining the issues of privacy and technological skill through the eyes of digital natives and digital immigrants, the challenges associated with medical e-professionalism become clear.

Can we delay the replacement of this component?-an asset management approach to the question [for electric utilities

DEFF Research Database (Denmark)

Østergaard, Jacob; Jensen, A. Norsk

2001-01-01

Asset management is emerging as a new approach on how to exploit an electric utility physical asset in the most profitable way. One of the major questions to answer by the asset management staff is when to do replacements? This is a difficult question, which require weighting of several parameter...... on Windows CE handheld computers which are presented in this paper. The calculations shown in the paper are based on this tool, and the software system is today available and used by Danish electric utilities....

Challenges in the management of juvenile idiopathic arthritis with etanercept

Directory of Open Access Journals (Sweden)

Clare E Pain

2009-03-01

Full Text Available Clare E Pain, Liza J McCannAlder Hey Children’s NHS Foundation Trust, Eaton Road, Liverpool, UKAbstract: Biologic agents have been designed with the help of immunological studies to target particular areas of the immune system which are thought to play a role in the pathogenesis of disease. Etanercept is a soluble anti-tumor necrosis factor alpha (TNF-α agent licensed for the treatment of active poly-articular juvenile idiopathic arthritis (JIA in children aged 4 to 17 years who have failed to respond to methotrexate alone, or who have been intolerant of methotrexate. The safety and efficacy of etanercept in this patient group has been established by one randomized controlled trial and several longitudinal studies. This, together with the fact that until recently etanercept was the only anti-TNF licensed in JIA, has made it the most common first choice biologic for many clinicians. However, there are still many unanswered questions about etanercept, including its efficacy and safety in different subtypes of JIA, in children under 4 years of age and in those with uveitis. There are still concerns about the long term safety of TNF antagonists in the pediatric age group and unanswered questions about increased risks of malignancy and infection. Although adult studies are useful to improve understanding of these risks, they are not a substitute for good quality pediatric research and follow-up studies. Adult trials often include greater numbers of patients. However, they evaluate a different population and drug behavior may vary in children due to differences in metabolism, growth and impact on a developing immune system. In addition, rheumatoid arthritis is a different disease than JIA. Clinicians need to carefully weigh up the risk benefit ratio of anti-TNF use in children with JIA and push for robust clinical trials to address the questions that remain unanswered. This article summarizes the evidence available for use of etanercept in children

Structured Attentions for Visual Question Answering

OpenAIRE

Zhu, Chen; Zhao, Yanpeng; Huang, Shuaiyi; Tu, Kewei; Ma, Yi

2017-01-01

Visual attention, which assigns weights to image regions according to their relevance to a question, is considered as an indispensable part by most Visual Question Answering models. Although the questions may involve complex relations among multiple regions, few attention models can effectively encode such cross-region relations. In this paper, we demonstrate the importance of encoding such relations by showing the limited effective receptive field of ResNet on two datasets, and propose to mo...

A Technique Socratic Questioning-Guided Discovery

OpenAIRE

M. Hakan Türkçapar; A. Emre Sargýn

2012-01-01

“Socratic Method” is a way of teaching philosophical thinking and knowledge by asking questions which was used by antique period greek philosopher Socrates. Socrates was teaching knowledge to his followers by asking questions and the conversation between them was named “Socratic Dialogues”. In this meaning, no novel knowledge is taught to the individual but only what is formerly known is reminded and rediscovered. The form of socratic questioning which is used during t...

Basic Physics Questions Addressed by Astrophysics

Science.gov (United States)

Mather, John C.

2009-01-01

Dark matter, dark energy, the Big Bang, testing relativity -- all are physics questions accessible to astrophysicists -- but all require new equipment. As Harwit's "Cosmic Discovery" pointed out, almost all great surprises in astronomy came from new equipment or new uses of equipment designed for other purposes, and many of those had military applications. I will outline prospects for new equipment and discuss how that equipment can be developed and built. Bigger and lighter mirrors, wavefront sensing and control, new detector technology, cryogenics -- each has its own social network, its own special possibilities, and its own funding sources outside science. I will discuss some examples drawn from real-life experience with the James Webb Space Telescope, a telescope that was said to have a "giggle factor" when it was proposed in 1995. Now each of the 10 major technologies has been brought to maturity, flight hardware is being built, and launch is planned for 2014. As an instrument builder all my life, I will speculate a little on what may be within our reach over the next few decades.

Traveling questions

DEFF Research Database (Denmark)

Hoeyer, Klaus

2016-01-01

In this paper, I argue that uncertainty and nonknowledge, and not just research results, can be important vehicles of translation through which genetic research participation comes to affect the lives of research participants. Based on interviews with participants in a genetic research project, I....... Research questions, and not just results, may serve as a generative form of knowledge that can travel as fast as any answer....

Altitudinal zonation among lizards of the genus Liolaemus: questions answered and unanswered questions Zonación altitudinal en lagartijas del género Liolaemus: preguntas respondidas y pendientes

Directory of Open Access Journals (Sweden)

JOHN H. CAROTHERS

2001-06-01

Full Text Available We review factors influencing Liolaemus distributions in the central Chilean Andes and suggest areas of future research. Our previous studies reveal that lizard parasites (ectoparasitic mites and ticks, and the endoparasite Plasmodium do not set Liolaemus altitudinal limits. Thermal tolerances do not appear to limit altitudinal distributions, although cold ambient temperatures dictate that only live-bearing species can occur above 2,400 m elevation. Three Liolaemus species specialize on elevationally restricted microhabitats. Liolaemus tenuis is found exclusively in or at the base of trees, which are typically below 1,800 m. Liolaemus leopardinus specializes on large rocky outcrops found at high altitudes. Liolaemus monticola uses smaller rocks: oviparity set its upper distributional limit on two transects, but on one transect this lizard and its rocky habitat virtually disappeared above 1,500 m. Interspecific competition among Liolaemus appeared unrelated to elevational distribution. We found no instances of parapatric distributions among pairs of Liolaemus species having similar niche requirements. Other researchers have found that predation does not correlate with elevation: its role in determining lizard species distributions depends on both predator and prey identities. We conclude that factors setting distributional limits of Liolaemus species vary depending on individual circumstances in time and space: where physiology may be relevant on one transect, preferred microhabitat availability may be important in anotherRevisamos los factores que influyen sobre las distribuciones de Liolaemus en los Andes del centro de Chile y sugerimos futuras avenidas de investigación. Nuestros estudios previos revelan que los parásitos (garrapatas y ácaros ectoparásitos y el endoparásito Plasmodium no influyen sobre los límites altitudinales de Liolaemus. Las tolerancias térmicas tampoco parecen limitar dichas distribuciones altitudinales, aunque las temperaturas ambientales frías determinan que sólo las especies vivíparas puedan sobrevivir arriba de los 2.400 m de altura. Tres especies de Liolaemus se especializan en microhábitats de distribución restringida en el gradiente altitudinal. Liolaemus tenuis se encuentra exclusivamente en la base de árboles, los cuales se distribuyen típicamente debajo de los 1.800 m. Liolaemus leopardinus se especializa en rocas grandes que se encuentran sólo en altitudes mayores. Liolaemus monticola usa rocas pequeñas: la oviparidad determina su límite distribucional superior en dos de los tres transectos examinados, y en el tercero esta especie y su habitat rocoso virtualmente desaparecen arriba de los 1.500 m. La competencia interespecífica entre Liolaemus aparentemente no se relaciona con su distribución altitudinal. No encontramos ejemplos de distribuciones parapátricas entre pares de especies de Liolaemus con similares requerimientos de nicho. Otros investigadores han encontrado que la depredación no se correlaciona con la altitud: su papel en determinar las distribuciones altitudinales de especies depende tanto de las densidades de predadores como de las presas. Concluímos que los factores determinantes de los límites de distribución de las especies de Liolaemus varían dependiendo de sus circunstancias individuales en el tiempo y el espacio: si bien la fisiología puede ser relevante en un transecto, la disponibilidad del microhábitat preferido puede ser importante en otro

Using Mind Maps to Make Student Questioning Effective: Learning Outcomes of a Principle-Based Scenario for Teacher Guidance

Science.gov (United States)

Stokhof, Harry; de Vries, Bregje; Bastiaens, Theo; Martens, Rob

2018-01-01

Student questioning is an important learning strategy, but rare in many classrooms, because teachers have concerns if these questions contribute to attaining curricular objectives. Teachers face the challenge of making student questioning effective for learning the curriculum. To address this challenge, a principle-based scenario for guiding effective student questioning was developed and tested for its relevance and practicality in two previous studies. In the scenario, which consists of a sequence of pedagogical activities, mind maps support teachers and students to explore and elaborate upon a core curriculum, by raising, investigating, and exchanging student questions. In this paper, a follow-up study is presented that tested the effectiveness of the scenario on student outcomes in terms of attainment of curricular objectives. Ten teachers and their 231 students participated in the study. Pre- and posttest mind maps were used to measure individual and collective learning outcomes of student questioning. Findings show that a majority of students progressed in learning the core curriculum and elaborated upon it. The findings suggest that visualizing knowledge construction in a shared mind map supports students to learn a core curriculum and to refine their knowledge structures.

Cosmetic Procedure Questions

Science.gov (United States)

... for Every Season How to Choose the Best Skin Care Products In This Section Dermatologic Surgery What is dermatologic ... for Every Season How to Choose the Best Skin Care Products Cosmetic Procedure Questions Want to look younger? Start ...

QUESTION ANSWERING SYSTEM DAN PENERAPANNYA PADA ALKITAB

Directory of Open Access Journals (Sweden)

Gunawan Gunawan

2006-01-01

Full Text Available Question answering system is a system that allows user to state his or her information need in the form of natural language question, and return short text excerpts or even phrases as an answer. The availability of a wide and various information source and improvements in the techniques of natural language processing, information extraction (wrapper, and information retrieval give a big effect on the development of question answering system, from just answering questions in a specific domain by consulting to structured information source such as database, and like in this research, answering any questions based on information stored in an unstructured text collection. A general architecture of question answering system based on text consists of six processing stages, i.e. question analysis, document collection preprocessing, candidate document selection, candidate document analysis, answer extraction, and response generation. Application of question answering system like AnswerBus, Mulder, and Webclopedia that are developed with its own characteristics has similar processing steps as in the general architecture. Answers returned by a question answering system need to be evaluated for performance measure. This research completed with a simple question answering system application using english Bible in World English Bible (WEB version as the source of information to answer some questions. Because specific domain is selected: Bible, questions that can be posed by user could ask about information in the Bible itself only. Question is also limited to three types of answers that can be supported by the application: person (who, location (where, and date (when. Abstract in Bahasa Indonesia : Question answering system (QA system adalah sistem yang mengijinkan user menyatakan kebutuhan informasinya dalam bentuk natural language question (pertanyaan dalam bahasa alami, dan mengembalikan kutipan teks singkat atau bahkan frase sebagai jawaban. Ketersediaan

Identifying trial recruitment uncertainties using a James Lind Alliance Priority Setting Partnership - the PRioRiTy (Prioritising Recruitment in Randomised Trials) study.

Science.gov (United States)

Healy, Patricia; Galvin, Sandra; Williamson, Paula R; Treweek, Shaun; Whiting, Caroline; Maeso, Beccy; Bray, Christopher; Brocklehurst, Peter; Moloney, Mary Clarke; Douiri, Abdel; Gamble, Carrol; Gardner, Heidi R; Mitchell, Derick; Stewart, Derek; Jordan, Joan; O'Donnell, Martin; Clarke, Mike; Pavitt, Sue H; Guegan, Eleanor Woodford; Blatch-Jones, Amanda; Smith, Valerie; Reay, Hannah; Devane, Declan

2018-03-01

Despite the problem of inadequate recruitment to randomised trials, there is little evidence to guide researchers on decisions about how people are effectively recruited to take part in trials. The PRioRiTy study aimed to identify and prioritise important unanswered trial recruitment questions for research. The PRioRiTy study - Priority Setting Partnership (PSP) included members of the public approached to take part in a randomised trial or who have represented participants on randomised trial steering committees, health professionals and research staff with experience of recruiting to randomised trials, people who have designed, conducted, analysed or reported on randomised trials and people with experience of randomised trials methodology. This partnership was aided by the James Lind Alliance and involved eight stages: (i) identifying a unique, relevant prioritisation area within trial methodology; (ii) establishing a steering group (iii) identifying and engaging with partners and stakeholders; (iv) formulating an initial list of uncertainties; (v) collating the uncertainties into research questions; (vi) confirming that the questions for research are a current recruitment challenge; (vii) shortlisting questions and (viii) final prioritisation through a face-to-face workshop. A total of 790 survey respondents yielded 1693 open-text answers to 6 questions, from which 1880 potential questions for research were identified. After merging duplicates, the number of questions was reduced to 496. Questions were combined further, and those that were submitted by fewer than 15 people and/or fewer than 6 of the 7 stakeholder groups were excluded from the next round of prioritisation resulting in 31 unique questions for research. All 31 questions were confirmed as being unanswered after checking relevant, up-to-date research evidence. The 10 highest priority questions were ranked at a face-to-face workshop. The number 1 ranked question was "How can randomised trials become

Disclosing harmful medical errors to patients: tackling three tough cases.

Science.gov (United States)

Gallagher, Thomas H; Bell, Sigall K; Smith, Kelly M; Mello, Michelle M; McDonald, Timothy B

2009-09-01

A gap exists between recommendations to disclose errors to patients and current practice. This gap may reflect important, yet unanswered questions about implementing disclosure principles. We explore some of these unanswered questions by presenting three real cases that pose challenging disclosure dilemmas. The first case involves a pancreas transplant that failed due to the pancreas graft being discarded, an error that was not disclosed partly because the family did not ask clarifying questions. Relying on patient or family questions to determine the content of disclosure is problematic. We propose a standard of materiality that can help clinicians to decide what information to disclose. The second case involves a fatal diagnostic error that the patient's widower was unaware had happened. The error was not disclosed out of concern that disclosure would cause the widower more harm than good. This case highlights how institutions can overlook patients' and families' needs following errors and emphasizes that benevolent deception has little role in disclosure. Institutions should consider whether involving neutral third parties could make disclosures more patient centered. The third case presents an intraoperative cardiac arrest due to a large air embolism where uncertainty around the clinical event was high and complicated the disclosure. Uncertainty is common to many medical errors but should not deter open conversations with patients and families about what is and is not known about the event. Continued discussion within the medical profession about applying disclosure principles to real-world cases can help to better meet patients' and families' needs following medical errors.

Frequently Asked Questions about Bunion Surgery

Science.gov (United States)

... A | Print | Share Frequently Asked Questions About Bunion Surgery Here are some frequently asked questions (FAQs) and ... best for you. 5. How can I avoid surgery? Sometimes observation of the bunion is all that ...

Finding Question-Answer Pairs from Online Forums

DEFF Research Database (Denmark)

Cong, Gao; Wang, Long; Lin, Chin-Yew

2008-01-01

Online forums contain a huge amount of valuable user generated content. In this paper we address the problem of extracting question-answer pairs from forums. Question-answer pairs extracted from forums can be used to help Question Answering services (e.g. Yahoo! Answers) among other applications...

How to…write a good research question

NARCIS (Netherlands)

Mattick, Karen; Johnston, Jenny; de la Croix, Anne

This paper, on writing research questions, is the first in a series that aims to support novice researchers within clinical education, particularly those undertaking their first qualitative study. Put simply, a research question is a question that a research project sets out to answer. Most research

The Socratic Method and Levels of Questioning.

Science.gov (United States)

Watson, Karilee

1980-01-01

Determines if instruction in the Socratic method would increase higher level questioning during peer teaching experiences in teacher education programs. Raters, using the higher order questioning strategy, evaluated 14 students. A significant increase in higher level questions being asked suggests the Socratic Method may be useful. (Author)

Old or not so old: that is the question for deltas and fans in Xanthe Terra, Mars

NARCIS (Netherlands)

Hauber, E.; Platz, T.; Reiss, D.; Le Deit, L.; Kleinhans, M.G.; Carbonneau, P.; Haas, T. de; Marra, W.A.

2013-01-01

Most aqueous activity on Mars (except the outflow channels) is thought to be older than ~3.8 Ga [1]. After a major and global environmental change [e.g., 2] of yet unknown reasons [3], the planet approached its current hyperarid climate. Despite this general agreement, many open questions

Question Answering for Dutch : Simple does it

NARCIS (Netherlands)

Hoekstra, A.H.; Hiemstra, Djoerd; van der Vet, P.E.; Huibers, Theo W.C.; Schobbens, Pierre-Yves; Vanhoof, Wim; Schwanen, Gabriel

2006-01-01

When people pose questions in natural language to search for information on the web, the role of question answering (QA) systems becomes important. In this paper the QAsystem simpleQA, capable of answering Dutch questions on which the answer is a person or a location, is described. The system's

A critical analysis of the majority judgment in F v Minister of Safety ...

African Journals Online (AJOL)

The majority judgment of Mogoeng CJ in F v Minister of Safety and Security 2012 1 ... norms now play an important role in deciding questions of vicarious liability. ... the conduct of the employee wrongdoer and the business of his employer as ...

Is long-term planning obsolete? A discussion of integrated resource planning in the Pacific Northwest U.S. and a scenario for its demise

International Nuclear Information System (INIS)

Morlan, T.H.

1995-01-01

Slides presented at The Power of Change Conference in Vancouver, British Columbia, Canada in April 1995 dealing with integrated resource planning were provided. The creation of the Northwest Power Planning Council and the Northwest Power Act were described, including the goals that the the Act is expected to achieve. The Council's planning innovations were listed including the first regional integrated resource plan, a consistent and comprehensive treatment of demand side resources, and development of risk- averse plans through explicit treatment of uncertain demands. Resource planning analytical framework, modelling approach and resource strategy components were described. Major policy thrusts of the first regional power plan were presented. Factors promoting a competitive power supply industry, characteristics of that industry, and its effects on existing utilities were identified. Implications of integrated resource planning on long-term planning were assessed. A list of yet unanswered questions were appended to stimulate thought and discussion

Beyond Candida albicans: Mechanisms of immunity to non-albicans Candida species

Science.gov (United States)

Whibley, Natasha; Gaffen, Sarah L.

2015-01-01

The fungal genus Candida encompasses numerous species that inhabit a variety of hosts, either as commensal microbes and/or pathogens. Candida species are a major cause of fungal infections, yet to date there are no vaccines against Candida or indeed any other fungal pathogen. Our knowledge of immunity to Candida mainly comes from studies on C. albicans, the most frequent species associated with disease. However, non-albicans Candida (NAC) species also cause disease and their prevalence is increasing. Although research into immunity to NAC species is still at an early stage, it is becoming apparent that immunity to C. albicans differs in important ways from non-albicans species, with important implications for treatment, therapy and predicted demographic susceptibility. This review will discuss the current understanding of immunity to NAC species in the context of immunity to C. albicans, and highlight as-yet unanswered questions. PMID:26276374

Structural fire resistance experimental research priority needs of U.S. industry

CERN Document Server

Almand, Kathleen H

2012-01-01

Structural Fire Resistance Experimental Research – Priority Needs of U.S. Industry provides a synthesis of stakeholder input to a prioritized agenda for research at the National Fire Research Laboratory (NFRL) at the National Institute of Standards and Technology (NIST) designed to accelerate the implementation of performance-based fire engineering for structures. The NFRL presents a broad range of unanswered questions regarding the performance of real structures in fire conditions, and informs performance-based design methods and standards in this field. The authors conducted a comprehensive literature review of large-scale structural fire testing and compiled research needs from a variety of sources. The book addresses major issues of broad concern in the fire community, such as real fire exposure and structural response, composite floor system performance, enhancing modeling performance, and understanding the embedded safety features in design methods. It concludes with a prioritized set of research reco...

Anti-VEGF strategies - from antibodies to tyrosine kinase inhibitors: background and clinical development in human cancer.

LENUS (Irish Health Repository)

Korpanty, Grzegorz

2012-01-01

Tumour angiogenesis (formation of new blood vessels supporting tumour growth and metastasis) is a result of complex interactions between the tumour and the surrounding microenvironment. Targeting tumours with anti-angiogenic therapy remains an exciting area of preclinical and clinical studies. Although many significant advances have been achieved and the clinical use of anti-angiogenic drugs is now well recognized in many solid malignancies, these therapies fall short of their anticipated clinical benefits and leave many unanswered questions like exact mechanism of action, patients\\' selection and monitoring response to anti-angiogenic drugs. Tumour angiogenesis is controlled by complex signaling cascades and ongoing research into molecular mechanisms of tumour angiogenesis not only helps to understand its basic mechanisms but hopefully will identify new therapeutic targets. In 2012, both monoclonal antibodies and small molecule tyrosine kinase inhibitors remain the two major clinically useful therapeutic options that interfere with tumour angiogenesis in many solid malignancies.

Intimate partner violence against women and the Nordic paradox.

Science.gov (United States)

Gracia, Enrique; Merlo, Juan

2016-05-01

Nordic countries are the most gender equal countries in the world, but at the same time they have disproportionally high prevalence rates of intimate partner violence (IPV) against women. High prevalence of IPV against women, and high levels of gender equality would appear contradictory, but these apparently opposite statements appear to be true in Nordic countries, producing what could be called the 'Nordic paradox'. Despite this paradox being one of the most puzzling issues in the field, this is a research question rarely asked, and one that remains unanswered. This paper explores a number of theoretical and methodological issues that may help to understand this paradox. Efforts to understand the Nordic paradox may provide an avenue to guide new research on IPV and to respond to this major public health problem in a more effective way. Copyright © 2016 Elsevier Ltd. All rights reserved.

[Chagas's disease and deep ecology: the anti-vectorial fight in question].

Science.gov (United States)

Siqueira-Batista, Rodrigo; Gomes, Andréia Patrícia; Rôças, Giselle; Cotta, Rosângela Minardi Mitre; Rubião, Eduardo Cárdenas Nogueira; Pissinatti, Alcides

2011-02-01

The inter-relations between man and the environment are among the main themes currently debated by the Brazilian public health. On such horizon, the questions concerning Chagas's disease are found to remain specially in the scope of the directed actions of control to the triatomine, the anti-vectorial fight , though already a century since its first description by Carlos Chagas, a major epidemiological problem in Latin America. Based on these considerations the present article will seek to discuss the main ecological aspects related to the American trypanosomiasis, emphasizing the control of the vectorial transmission in the context of the deep ecology.

"I didn't write the questions!" - Negotiating telephone-survey questions on birth timing

Directory of Open Access Journals (Sweden)

Marian May

2008-06-01

Full Text Available This paper examines interviewer-respondent interaction in the collection of demographic data. Conversation analysis (CA makes transparent the interaction between an interviewer and 25 respondents on a question about pregnancy and birth timing in an Australian telephone survey, Negotiating the Life Course. The analysis focuses on the troubles that occur and the work interviewers do to fit respondents' answers to the survey researcher's categories. Interviewers are shown to act as mediators in difficult interaction, with responses often distorted by question format, the imperative of achieving an allowed response, and the need to keep the respondent in the survey.

[Pohoda no. I (death on music festival)].

Science.gov (United States)

Straka, I; Stuller, F; Krajcovic, J; Novomeský, F

2011-07-01

A fatal accident of a young man, visitor of the summer music festival, shocked the whole Slovak society. Many unanswered questions concerned a causality of the incident arose immediately. Altough most questions have been focused to technical experts concerning the cause of a tent fall, the forensic medicine can bring some important reflections and conclusions, too. An absence of natural defense mechanisms of the accident's victim should be explained only through malignant affection of the body reflectoris reactions by exogenous substance, which might depress natural senzoric or motoric response while being in acute danger from falling tent's construction.

Water vapour flux divergence over the Arabian Sea during 1987 summer monsoon using satellite data

Digital Repository Service at National Institute of Oceanography (India)

Vinayachandran, P.N.; RameshKumar, M.R.

the AS or the southern Indian Ocean. Another question which remains unanswered is whether all the NFD over AS is utilized only for precipitation over the Indian subcontinent or part of it is utilized for precipitation over the other southeast Asian countries. Only a... detailed and systematic surface and upper air data collection programme over the tropical Indian Ocean can throw light on the above questions. WATER VAPOUR FLUX DIVERGENCE OVER THE ARABIAN SEA 207 500 60’ 700 80” 500 60” 70” 500 60’ 70” 60” 700 Fig. 7...

Designing effective questions for classroom response system teaching

Science.gov (United States)

Beatty, Ian D.; Gerace, William J.; Leonard, William J.; Dufresne, Robert J.

2006-01-01

Classroom response systems can be powerful tools for teaching physics. Their efficacy depends strongly on the quality of the questions. Creating effective questions is difficult and differs from creating exam and homework problems. Each classroom response system question should have an explicit pedagogic purpose consisting of a content goal, a process goal, and a metacognitive goal. Questions can be designed to fulfill their purpose through four complementary mechanisms: directing students' attention, stimulating specific cognitive processes, communicating information to the instructor and students via classroom response system-tabulated answer counts, and facilitating the articulation and confrontation of ideas. We identify several tactics that are useful for designing potent questions and present four "makeovers" to show how these tactics can be used to convert traditional physics questions into more powerful questions for a classroom response system.

30 CFR 250.1200 - Question index table.

Science.gov (United States)

2010-07-01

... 30 Mineral Resources 2 2010-07-01 2010-07-01 false Question index table. 250.1200 Section 250.1200 Mineral Resources MINERALS MANAGEMENT SERVICE, DEPARTMENT OF THE INTERIOR OFFSHORE OIL AND GAS AND SULPHUR... Security § 250.1200 Question index table. The table in this section lists questions concerning Oil and Gas...

Using Targeted Active-Learning Exercises and Diagnostic Question Clusters to Improve Students' Understanding of Carbon Cycling in Ecosystems

Science.gov (United States)

Maskiewicz, April Cordero; Griscom, Heather Peckham; Welch, Nicole Turrill

2012-01-01

In this study, we used targeted active-learning activities to help students improve their ways of reasoning about carbon flow in ecosystems. The results of a validated ecology conceptual inventory (diagnostic question clusters [DQCs]) provided us with information about students' understanding of and reasoning about transformation of inorganic and organic carbon-containing compounds in biological systems. These results helped us identify specific active-learning exercises that would be responsive to students' existing knowledge. The effects of the active-learning interventions were then examined through analysis of students' pre- and postinstruction responses on the DQCs. The biology and non–biology majors participating in this study attended a range of institutions and the instructors varied in their use of active learning; one lecture-only comparison class was included. Changes in pre- to postinstruction scores on the DQCs showed that an instructor's teaching method had a highly significant effect on student reasoning following course instruction, especially for questions pertaining to cellular-level, carbon-transforming processes. We conclude that using targeted in-class activities had a beneficial effect on student learning regardless of major or class size, and argue that using diagnostic questions to identify effective learning activities is a valuable strategy for promoting learning, as gains from lecture-only classes were minimal. PMID:22383618

Using targeted active-learning exercises and diagnostic question clusters to improve students' understanding of carbon cycling in ecosystems.

Science.gov (United States)

Maskiewicz, April Cordero; Griscom, Heather Peckham; Welch, Nicole Turrill

2012-01-01

In this study, we used targeted active-learning activities to help students improve their ways of reasoning about carbon flow in ecosystems. The results of a validated ecology conceptual inventory (diagnostic question clusters [DQCs]) provided us with information about students' understanding of and reasoning about transformation of inorganic and organic carbon-containing compounds in biological systems. These results helped us identify specific active-learning exercises that would be responsive to students' existing knowledge. The effects of the active-learning interventions were then examined through analysis of students' pre- and postinstruction responses on the DQCs. The biology and non-biology majors participating in this study attended a range of institutions and the instructors varied in their use of active learning; one lecture-only comparison class was included. Changes in pre- to postinstruction scores on the DQCs showed that an instructor's teaching method had a highly significant effect on student reasoning following course instruction, especially for questions pertaining to cellular-level, carbon-transforming processes. We conclude that using targeted in-class activities had a beneficial effect on student learning regardless of major or class size, and argue that using diagnostic questions to identify effective learning activities is a valuable strategy for promoting learning, as gains from lecture-only classes were minimal.

The Significance of Sexuality and Intimacy in the Lives of Older African Americans With HIV/AIDS

Science.gov (United States)

Nevedal, Andrea; Sankar, Andrea

2016-01-01

Purpose of the Study: Aging and HIV/AIDS research focuses primarily on standardized clinical, social, and behavioral measures, leaving unanswered questions about how this chronic and stigmatizing condition affects life course expectations and the meaning of aging with the disease. Utilizing Gaylene Becker’s (1997) life course disruption theory, we explored older African Americans’ experiences of living with HIV/AIDS. Design and Methods: A purposive sample (N = 43) of seropositive African Americans aged 50 and older was selected from a parent study. Thirteen participants completed one semi-structured in-depth interview on life course expectations and experiences of living with HIV/AIDS. Interview transcripts were analyzed using standard qualitative coding and thematic analysis. Results: Responding to broad, open-ended questions about the impact of HIV on life course expectations, participants emphasized how HIV limited their ability to experience sexuality and intimacy. Two major themes emerged, damaged sexuality and constrained intimacy. Implications: Older African Americans’ discussions of living with HIV focused on the importance of and the challenges to sexuality and intimacy. Researchers and clinicians should be attentive to significant and ongoing HIV-related challenges to sexuality and intimacy facing older African Americans living with HIV/AIDS. PMID:26035889

Questions and dependency in intuitionistic logic

NARCIS (Netherlands)

Ciardelli, Ivano; Iemhoff, Rosalie; Yang, Fan

2017-01-01

In recent years, the logic of questions and dependencies has been investigated in the closely related frameworks of inquisitive logic and dependence logic. These investigations have assumed classical logic as the background logic of statements, and added formulas expressing questions and

Questions and Answers About Nuclear Power Plants.

Science.gov (United States)

Environmental Protection Agency, Washington, DC.

This pamphlet is designed to answer many of the questions that have arisen about nuclear power plants and the environment. It is organized into a question and answer format, with the questions taken from those most often asked by the public. Topics include regulation of nuclear power sources, potential dangers to people's health, whether nuclear…

Mergers and Product Quality: Evidence from the Airline Industry

OpenAIRE

Chen, Yongmin; Gayle, Philip

2013-01-01

Retrospective studies of horizontal mergers have focused on their price effects, leaving the important question of how mergers affect product quality largely unanswered. This paper empirically investigates this issue for two recent airline mergers: Delta/Northwest and Continental/United. Consistent with the theoretical premise that mergers improve coordination but diminish competitive pressure for quality provision, we find: (i) each merger is associated with a quality increase in markets whe...

Diabetic Cardiomyopathy: Bench to Bedside

Science.gov (United States)

Schilling, Joel D.; Mann, Douglas L.

2012-01-01

The study of diabetic cardiomyopathy (diabetic CM) is an area of significant interest given the strong association between diabetes and the risk of heart failure. Many unanswered questions remain regarding the clinical definition and pathogenesis of this metabolic cardiomyopathy. This article reviews the current understanding of diabetic CM with a particular emphasis on the unresolved issues that have limited translation of scientific discovery to patient bedside. PMID:22999244

The Dent Stage of Maize Kernels Is the Most Conducive for Fumonisin Biosynthesis under Field Conditions ▿

OpenAIRE

Picot, Adeline; Barreau, Christian; Pinson-Gadais, Laëtitia; Piraux, François; Caron, Daniel; Lannou, Christian; Richard-Forget, Florence

2011-01-01

The fungal pathogen Fusarium verticillioides infects maize ears and produces fumonisins, known for their adverse effects on human and animal health. Basic questions remain unanswered regarding the kernel stage(s) associated with fumonisin biosynthesis and the kernel components involved in fumonisin regulation during F. verticillioides-maize interaction under field conditions. In this 2-year field study, the time course of F. verticillioides growth and fumonisin accumulation in developing maiz...

[Quantified self movement--the new mantra of life insurance companies].

Science.gov (United States)

Becher, St

2016-06-01

Wearables are small personal minicomputers that register biometric data. In such a way, the insurance industry hopes to create new sales opportunities and products, and simplify underwriting. Lower premiums will promote the use of wearables. The related possibilities and unanswered questions are discussed in this article. Utilisation of big data offers the insurance industry a range of new opportunities. The benefit must be proven in the future, however.

Considerations for the rational design of a Chlamydia vaccine

OpenAIRE

Liang, Steven; Bulir, David; Kaushic, Charu; Mahony, James

2016-01-01

ABSTRACT Chlamydia trachomatis is the leading cause of preventable blindness and the most common bacterial sexually transmitted infection. Remarkable progress in vaccine research over the past six?decades has led to the advancement of novel C. trachomatis vaccine candidates into clinical trials. However, many questions regarding the role of specific cellular populations and molecular mechanisms in protective immunity against human C. trachomatis genital tract infections remain unanswered. Bio...

Technology-assisted education in graduate medical education: a review of the literature

OpenAIRE

Jwayyed, Sharhabeel; Stiffler, Kirk A; Wilber, Scott T; Southern, Alison; Weigand, John; Bare, Rudd; Gerson, Lowell W

2011-01-01

Studies on computer-aided instruction and web-based learning have left many questions unanswered about the most effective use of technology-assisted education in graduate medical education. Objective We conducted a review of the current medical literature to report the techniques, methods, frequency and effectiveness of technology-assisted education in graduate medical education. Methods A structured review of MEDLINE articles dealing with "Computer-Assisted Instruction," "Internet or World W...

Inclusive research and inclusive education: why connecting them makes sense for teachers’ and learners’ democratic development of education

OpenAIRE

Nind, Melanie

2014-01-01

Following pushes from the disability movement(s) and increased interest in children and young people becoming involved in research concerning them, inclusive research is growing within and beyond education establishments. Yet this arena is alive with interesting and largely unanswered questions. This paper discusses some of them: What do inclusive research and inclusive education have in common? Where have the moves towards inclusive (participatory and emancipatory) research happened and why?...

Spinal Cord Stimulation for the Relief of Pain: Proceedings of a Symposium during the 4th International Congress of the International Neuromodulation Society, September 16-20, 1998, Lucerne, Switzerland.

Science.gov (United States)

Oakley, J C

1999-07-01

Spinal cord stimulation has become an accepted technique used in the management of chronic neuropathic pain syndromes. However, a number of problematic questions remain unanswered. This introduction states some of these problems and concentrates on the problem of whether low back pain can be relieved by stimulation. This paper introduces subsequent contributions to this symposium, which offer some interesting new techniques, and attempts to answer some of the problems presented.

Using item response theory to explore the psychometric properties of extended matching questions examination in undergraduate medical education

Directory of Open Access Journals (Sweden)

Lawton Gemma

2005-03-01

Full Text Available Abstract Background As assessment has been shown to direct learning, it is critical that the examinations developed to test clinical competence in medical undergraduates are valid and reliable. The use of extended matching questions (EMQ has been advocated to overcome some of the criticisms of using multiple-choice questions to test factual and applied knowledge. Methods We analysed the results from the Extended Matching Questions Examination taken by 4th year undergraduate medical students in the academic year 2001 to 2002. Rasch analysis was used to examine whether the set of questions used in the examination mapped on to a unidimensional scale, the degree of difficulty of questions within and between the various medical and surgical specialties and the pattern of responses within individual questions to assess the impact of the distractor options. Results Analysis of a subset of items and of the full examination demonstrated internal construct validity and the absence of bias on the majority of questions. Three main patterns of response selection were identified. Conclusion Modern psychometric methods based upon the work of Rasch provide a useful approach to the calibration and analysis of EMQ undergraduate medical assessments. The approach allows for a formal test of the unidimensionality of the questions and thus the validity of the summed score. Given the metric calibration which follows fit to the model, it also allows for the establishment of items banks to facilitate continuity and equity in exam standards.

Impacts of Socratic questioning on moral reasoning of nursing students.

Science.gov (United States)

Torabizadeh, Camellia; Homayuni, Leyla; Moattari, Marzieh

2018-03-01

Nurses are often faced with complex situations that made them to make ethical decisions; and to make such decisions, they need to possess the power of moral reasoning. Studies in Iran show that the majority of nursing students lack proper ethical development. Socratic teaching is a student-centered method which is strongly opposed to the lecturing method. This study was conducted to evaluate the impacts of Socratic questioning on the moral reasoning of the nursing students. In a quasi-experimental study, Crisham's Nursing Dilemma Test was used to evaluate the results of three groups before, immediately after, and 2 months after intervention. The data were analyzed using the SPSS statistical software (v 15). Participants and research context: Through random allocation, 103 nursing students were divided into three groups. In experiment group 1 (37 students), intervention consisted of Socratic questioning-based sessions on ethics and how to deal with moral dilemmas; experiment group 2 (33 students) attended a 4-h workshop; and the control group (33 students) was not subject to any interventions. Signed informed consent forms: This research was approved by the Ethics Committee of the University. All the participants signed written informed consents. There were significant differences between experiment group 1 and experiment group 2's pre-test and post-test scores on moral reasoning (p ≤ 0.001, p ≤ 0.001), nursing principled thinking (p ≤ 0.001, p ≤ 0.001), and practical considerations (p ≤ 0.001, p ≤ 0.031). Both the teaching approaches improved the subjects' moral reasoning; however, Socratic questioning proved more effective than lecturing. Compared to other similar studies in Iran and other countries, the students had inadequate moral reasoning competence. This study confirms the need for the development of an efficient course on ethics in the nursing curriculum. Also, it appears that Socratic questioning is an effective method to teach nursing ethics

Factors influencing a nurse's decision to question medication administration in a neonatal clinical care unit.

Science.gov (United States)

Aydon, Laurene; Hauck, Yvonne; Zimmer, Margo; Murdoch, Jamee

2016-09-01

The aim of this study was to identify factors that influence nurse's decisions to question concerning aspects of medication administration within the context of a neonatal clinical care unit. Medication error in the neonatal setting can be high with this particularly vulnerable population. As the care giver responsible for medication administration, nurses are deemed accountable for most errors. However, they are recognised as the forefront of prevention. Minimal evidence is available around reasoning, decision making and questioning around medication administration. Therefore, this study focuses upon addressing the gap in knowledge around what nurses believe influences their decision to question. A critical incident design was employed where nurses were asked to describe clinical incidents around their decision to question a medication issue. Nurses were recruited from a neonatal clinical care unit and participated in an individual digitally recorded interview. One hundred and three nurses participated between December 2013-August 2014. Use of the constant comparative method revealed commonalities within transcripts. Thirty-six categories were grouped into three major themes: 'Working environment', 'Doing the right thing' and 'Knowledge about medications'. Findings highlight factors that influence nurses' decision to question issues around medication administration. Nurses feel it is their responsibility to do the right thing and speak up for their vulnerable patients to enhance patient safety. Negative dimensions within the themes will inform planning of educational strategies to improve patient safety, whereas positive dimensions must be reinforced within the multidisciplinary team. The working environment must support nurses to question and ultimately provide safe patient care. Clear and up to date policies, formal and informal education, role modelling by senior nurses, effective use of communication skills and a team approach can facilitate nurses to

What Do Patients Want to Know? Questions and Concerns Regarding Mammography Expressed Through Social Media.

Science.gov (United States)

Charlie, Abbas M; Gao, Yiming; Heller, Samantha L

2017-12-05

The purpose of this project is to identify questions and concerns patients have regarding breast cancer screening mammography to establish priorities in patient education and health care communication. A content analysis of posted questions (June 2010 to February 2017) containing the keywords mammogram and mammography was conducted on the social media question and answer website Quora (Quora Inc, Mountainview, California). Question topic, responses, and number of views were recorded. Comparisons were made by respondent type (medical professional or nonmedical professional) for screening recommendations and accompanying evidence. Descriptive statistics were employed to summarize the results. Overall, 197,620 views of mammography-related questions were identified, focused on 51 questions and 172 responses (51 of 172 [29.7%] by medical professionals [n = 25]; 121 of 172 [70.3%] by nonmedical professionals [n = 121]). Mammographic efficacy (16 of 51 [31.4%]) and screening guidelines (10 of 51 [19.6%]) were the most frequently queried topics. Overall, the majority of respondents were supportive of screening mammography. Most medical professionals recommended screening mammography starting at age 40, even after revisions in guidelines. Among nonmedical professionals, 4 of 22 (18.2%) were against screening mammography with less consensus regarding appropriate age of initial screen. Health society websites and journal articles were the most commonly referenced sources among medical and nonmedical professionals, respectively. A considerable interest in screening mammography guidelines and mammographic efficacy exists among users who seek health information on a social media question and answer website. Awareness of such platforms allows a unique opportunity for targeted health education and dissemination of accurate information, which may be able to reach a potentially untapped or hard-to-reach patient population. Copyright © 2017 American College of Radiology

Conducting systematic reviews of intervention questions I: Writing the review protocol, formulating the question and searching the literature.

Science.gov (United States)

O'Connor, A M; Anderson, K M; Goodell, C K; Sargeant, J M

2014-06-01

This article is the fourth of six articles addressing systematic reviews in animal agriculture and veterinary medicine. Previous articles in the series have introduced systematic reviews, discussed study designs and hierarchies of evidence, and provided details on conducting randomized controlled trials, a common design for use in systematic reviews. This article describes development of a review protocol and the first two steps in a systematic review: formulating a review question, and searching the literature for relevant research. The emphasis is on systematic reviews of questions related to interventions. The review protocol is developed prior to conducting the review and specifies the plan for the conduct of the review, identifies the roles and responsibilities of the review team and provides structured definitions related to the review question. For intervention questions, the review question should be defined by the PICO components: population, intervention, comparison and outcome(s). The literature search is designed to identify all potentially relevant original research that may address the question. Search terms related to some or all of the PICO components are entered into literature databases, and searches for unpublished literature also are conducted. All steps of the literature search are documented to provide transparent reporting of the process. © 2014 Blackwell Verlag GmbH.

To lead or to manage? That is a question the review of leadership theories

OpenAIRE

Lipińska-Grobelny, Agnieszka

2005-01-01

One of the major domain of empirical and theoretical interest in psychology of organisation and management is a leadership. Long ago professionals and scientists have been searching for universal prescription for an effective management. The inventor for sure will become one of the richest people in the world. Instantly, the question arises if such a universal prescription really exists? This article presents the survey of leadership theories as an important aspect of a managem...

How do 5-year-olds understand questions?

DEFF Research Database (Denmark)

Sauerland, Uli; Grohmann, Kleanthes; Teresa Guasti, Maria

2016-01-01

developing children across 19 European countries, 18 different languages, and 7 language (sub-)families. The study investigated the effects of two factors on question formation: (a) whether the question contains a simple interrogative word like ‘who’ or a complex one like ‘which princess’, and (b) whether......The comprehension of constituent questions is an important topic for language acquisition research and for applications in the diagnosis of language impairment. This article presents the results of a study investigating the comprehension of different types of questions by 5-year-old, typically...... the question word was related to the sentential subject or object position of the verb. The findings show that there is considerable variation among languages, but the two factors mentioned consistently affect children’s performance. The cross-linguistic variation shows that three linguistic factors facilitate...

Environmental Ethics: Questions for Adult Education.

Science.gov (United States)

Parker, Jenneth

1993-01-01

Presents a series of questions through which adult educators can explore controversial questions of environmental values and moral behavior in their programs. The subjects include geography, local history, natural history, economics, politics, business, labor education, world affairs, literature, women's studies, psychology, and courses for the…

From Question Answering to Visual Exploration

Energy Technology Data Exchange (ETDEWEB)

McColgin, Dave W.; Gregory, Michelle L.; Hetzler, Elizabeth G.; Turner, Alan E.

2006-08-11

Research in Question Answering has focused on the quality of information retrieval or extraction using the metrics of precision and recall to judge success; these metrics drive toward finding the specific best answer(s) and are best supportive of a lookup type of search. These do not address the opportunity that users? natural language questions present for exploratory interactions. In this paper, we present an integrated Question Answering environment that combines a visual analytics tool for unstructured text and a state-of-the-art query expansion tool designed to compliment the cognitive processes associated with an information analysts work flow. Analysts are seldom looking for factoid answers to simple questions; their information needs are much more complex in that they may be interested in patterns of answers over time, conflicting information, and even related non-answer data may be critical to learning about a problem or reaching prudent conclusions. In our visual analytics tool, questions result in a comprehensive answer space that allows users to explore the variety within the answers and spot related information in the rest of the data. The exploratory nature of the dialog between the user and this system requires tailored evaluation methods that better address the evolving user goals and counter cognitive biases inherent to exploratory search tasks.

'Any questions?'--Clinicians' usage of invitations to ask questions (IAQs) in outpatient plastic surgery consultations.

Science.gov (United States)

Bristowe, Katherine; Patrick, Peter L

2014-12-01

To explore use of 'Invitations to Ask Questions' (IAQs) by plastic surgeons in outpatient consultations, and consider how type of IAQ impacts on patients' responses to, and recollection of, IAQs. Descriptive study: 63 patients were audio recorded in consultation with 5 plastic surgeons, and completed a brief questionnaire immediately after the consultation. Consultation transcripts were analyzed using inductive qualitative methods of Discourse Analysis and compared with questionnaire findings. A taxonomy of IAQs was developed, including three types of IAQ (Overt, Covert, and Borderline). Overt IAQs were rarely identified, and almost all IAQs occurred in the closing stages of the consultation. However, when an overt IAQ was used, patients always recollected being asked if they had any questions after the consultation. Patients are rarely explicitly offered the opportunity to ask questions. When this does occur, it is often in the closing stages of the consultation. Clinicians should openly encourage patients to ask questions frequently throughout the consultation, and be mindful that subtle differences in construction of these utterances may impact upon interpretation. Clear communication, of message and intention, is essential in clinical encounters to minimize misunderstanding, misinterpretation, or missed opportunities for patients to raise concerns. Copyright © 2014. Published by Elsevier Ireland Ltd.

Probability of climatic change. Identification of key questions

International Nuclear Information System (INIS)

Fransen, W.

1995-01-01

Addressing the question what the probability is of an anthropogenically induced change in the climate, leads to a number of other, underlying questions. These questions, which deal with the characteristics of climate, of climatic change, and of probabilistic statements on climatic change, should be addressed first. The long-term objective of the underlying study, i.e. a quantitative assessment of the risks and opportunities of the predicted climatic change, sets the context against which of those questions should be answered. In addition, this context induces extra questions, i.e. about the characteristics of risk

Question-answer sequences in survey interviews

NARCIS (Netherlands)

Dijkstra, W.; Ongena, Y.P.

2006-01-01

Interaction analysis was used to analyze a total of 14,265 question-answer sequences of (Q-A Sequences) 80 questions that originated from two face-to-face and three telephone surveys. The analysis was directed towards the causes and effects of particular interactional problems. Our results showed

Six Open Questions about the Migration of Engineered Nano-Objects from Polymer-Based Food Contact Materials: A Review

DEFF Research Database (Denmark)

Jokar, Maryam; Pedersen, Gitte Alsing; Löschner, Katrin

2017-01-01

. Current research focusing on FCMs has often reached inconsistency regarding migration of ENOs. The scope of this critical review is to give a concise overview of the most relevant aspects of the subject, and to identify and discuss the major open questions in relation to migration of ENOs from FCMs....... This includes the very fundamental questions whether ENOs can migrate from FCMs at all and what the potential release mechanisms of ENOs could be. The inconsistency of findings from experimental studies is highlighted based on the example of silver nanoparticle migration from polymer-based FCMs. Challenges...

Question Word in the Mandarin Language

Directory of Open Access Journals (Sweden)

Xu Yunyu

2016-12-01

Full Text Available In an interrogative sentence in Mandarin language, a question word can be placed in the beginning, middle or end of a sentence. Because of the different nation and culture, when a foreign student learns Mandarin, they find it difficult to understand the question words and the position of the question words in that language. Because of that, the writer proposes to explain such problems. This research aims to find out what are the types of question words in Mandarin, and also to explain the function and usage of question words in the Mandarin interrogative sentence. An interrogative sentence is a very important sentence. In Mandarin, the following question words: 谁(shuí “Who”，在哪里(zài nǎli “where”, 在哪儿(zài nǎ’er “where”，为什么(wèi shénme “why”, 怎么(zěnme “why”，多少（duō shǎo） “how many”，多久(duō jiǔ “how long”，什么时候 (shénme shíhòu “when”，什么(shénme “what”，做什么(zuò shénme “why”，干 什么(gàn shénme “why”，干嘛(gànma “why” and so on are used to ask “who”, “where”, “what”, “how much”, “when”, “what time”, and “why”. Those words have different functions and usage. Each sentence has a certain structure and word order. A question word can be placed in the beginning, middle, or end of a sentence. When the place is changed, there is a possibility of miscommunication.   DOI: https://doi.org/10.24071/llt.2013.160106

Academic Oversight: Asking Questions, Building Bridges

Science.gov (United States)

Wilson, E. B.

2011-01-01

The best way for trustees to fully understand and fulfill their responsibility to ensure that their institution is providing quality education and meeting academic goals is by asking appropriate questions. Collaboration among trustees, faculty members, and administrators is essential to framing questions from a strategic perspective. Just the act…

37 CFR 354.2 - Novel questions.

Science.gov (United States)

2010-07-01

... of law, referral to the Register of Copyrights by the Copyright Royalty Judges is mandatory. A “novel... discretionary referral of material questions of copyright law to the Register of Copyrights by the Copyright... Copyrights in resolving material questions of substantive law is binding upon the Copyright Royalty Judges...

US fertility prevention as poverty prevention: an empirical question and social justice issue.

Science.gov (United States)

Romero, Diana; Agénor, Madina

2009-01-01

This paper examines the impact of the US welfare reform family-cap policy on the childbearing decisions of poor and low-income women by posing two complementary questions, both placed within a broader historical context. Specifically, it raises an empirical question pertaining to the family cap's effectiveness and a social justice question pertaining to the policy's ethical and legal justification in terms of human and reproductive rights. To address the first question, a thorough review of past and current research pertaining to the family cap at both the state and national levels is provided. The second question is addressed with an overview of international human and reproductive rights documents of relevance to the family-cap policy, as well as an analysis of the covenants' numerous components with which the family cap is in conflict. Finally, this paper situates the family cap in its historical context by investigating previous governmental attempts to control and regulate the reproductive health and rights of poor women and women of color in the United States. The majority of empirical analyses of the family cap have found that the policy has not had an impact on poor women's reproductive health behaviors. In addition, the exclusive application of this policy to poor women receiving cash assistance is demonstrated to be in violation of eight international human and reproductive rights documents, several of which the US is a signatory. These two findings make a strong case that policy makers and social and health researchers alike critically reexamine whether a policy that has not achieved its ostensible goal and is applied in a disparate manner-primarily to poor women and families and women of color-should continue to be implemented by the states.

Robustness Analysis of Visual QA Models by Basic Questions

KAUST Repository

Huang, Jia-Hong

2017-09-14

Visual Question Answering (VQA) models should have both high robustness and accuracy. Unfortunately, most of the current VQA research only focuses on accuracy because there is a lack of proper methods to measure the robustness of VQA models. There are two main modules in our algorithm. Given a natural language question about an image, the first module takes the question as input and then outputs the ranked basic questions, with similarity scores, of the main given question. The second module takes the main question, image and these basic questions as input and then outputs the text-based answer of the main question about the given image. We claim that a robust VQA model is one, whose performance is not changed much when related basic questions as also made available to it as input. We formulate the basic questions generation problem as a LASSO optimization, and also propose a large scale Basic Question Dataset (BQD) and Rscore (novel robustness measure), for analyzing the robustness of VQA models. We hope our BQD will be used as a benchmark for to evaluate the robustness of VQA models, so as to help the community build more robust and accurate VQA models.

Robustness Analysis of Visual QA Models by Basic Questions

KAUST Repository

Huang, Jia-Hong; Alfadly, Modar; Ghanem, Bernard

2017-01-01

Visual Question Answering (VQA) models should have both high robustness and accuracy. Unfortunately, most of the current VQA research only focuses on accuracy because there is a lack of proper methods to measure the robustness of VQA models. There are two main modules in our algorithm. Given a natural language question about an image, the first module takes the question as input and then outputs the ranked basic questions, with similarity scores, of the main given question. The second module takes the main question, image and these basic questions as input and then outputs the text-based answer of the main question about the given image. We claim that a robust VQA model is one, whose performance is not changed much when related basic questions as also made available to it as input. We formulate the basic questions generation problem as a LASSO optimization, and also propose a large scale Basic Question Dataset (BQD) and Rscore (novel robustness measure), for analyzing the robustness of VQA models. We hope our BQD will be used as a benchmark for to evaluate the robustness of VQA models, so as to help the community build more robust and accurate VQA models.

"Wh"-Questions in the English Language

Science.gov (United States)

Mowarin, Macaulay

2011-01-01

This paper analyzes "wh"-questions in the English Language based mainly on Chomsky's Minimalist Programme of transformational grammar as the theoretical model. The four main objectives of this paper are as follows: first, it undertakes a cross linguistic typological analysis of "wh"-questions and it then discusses the derivation of…

Paracetamol, Ibuprofen, and Recurrent Major Cardiovascular and Major Bleeding Events in 19 120 Patients With Recent Ischemic Stroke.

Science.gov (United States)

Gonzalez-Valcarcel, Jaime; Sissani, Leila; Labreuche, Julien; Bousser, Marie-Germaine; Chamorro, Angel; Fisher, Marc; Ford, Ian; Fox, Kim M; Hennerici, Michael G; Mattle, Heinrich P; Rothwell, Peter M; Steg, Philippe Gabriel; Vicaut, Eric; Amarenco, Pierre

2016-04-01

The presumed safety of paracetamol in high-cardiovascular risk patients has been questioned. We determined whether paracetamol or ibuprofen use is associated with major cardiovascular events (MACE) or major bleeding in 19 120 patients with recent ischemic stroke or transient ischemic attack of mainly atherothrombotic origin included in the Prevention of cerebrovascular and cardiovascular events of ischemic origin with terutroban in patients with a history of ischemic stroke or transient ischemic attack (PERFORM) trial. We performed 2 nested case-control analysis (2153 cases with MACE during trial follow-up and 4306 controls matched on Essen stroke risk score; 809 cases with major bleeding matched with 1616 controls) and a separate time-varying analysis. 12.3% were prescribed paracetamol and 2.5% ibuprofen. Median duration of treatment was 14 (interquartile range 5-145) days for paracetamol and 9 (5-30) days for ibuprofen. Paracetamol, but not ibuprofen, was associated with increased risk of MACE (odds ratio 1.21, 95% confidence interval [CI] 1.04-1.42) or a major bleeding (odds ratio 1.60, 95% CI 1.26-2.03), with no impact of daily dose and duration of paracetamol treatment. Time-varying analysis found an increased risk of MACE with both paracetamol (hazard ratio 1.22, 95% CI 1.05-1.43) and ibuprofen (hazard ratio 1.47, 95% CI 1.06-2.03) and of major bleeding with paracetamol (hazard ratio 1.95, 95% CI 1.45-2.62). There was a weak and inconsistent signal for association between paracetamol or ibuprofen and MACE or major bleeding, which may be related to either a genuine but modest effect of these drugs or to residual confounding. http://www.isrctn.com. Unique identifier: ISRCTN66157730. © 2016 American Heart Association, Inc.

Tests of fundamental symmetries with trapped antihydrogen

DEFF Research Database (Denmark)

Rasmussen, Chris Ørum

2016-01-01

Antihydrogen is the simplest pure antimatter atomic system, and it allows for direct tests of CPT symmetry as well as the weak equivalence principle. Furthermore the study of antihydrogen may provide clues to the matter- antimatter asymmetry observed in the universe - one of the major unanswered...

Three Key Questions on Measuring Learning

Science.gov (United States)

McTighe, Jay

2018-01-01

The author examines three essential questions on educational assessment: What really matters in a contemporary education? How should we assess those things that matter? How might our assessments enhance learning that matters, not just measure it? In answering these question, he argues that schools need a broader collection of measures, with a…

The acquisition of wh-questions in Russian

Directory of Open Access Journals (Sweden)

Nina Rojina

2005-02-01

Full Text Available In this paper, I study the acquisition of wh-questions in Russian by one Russian-speaking child from an early stage of syntactic development. For my analysis, I follow Plunkett (1992:73 in adopting a weak version of the Continuity Hypothesis where all the principles of UG are available from the outset of the acquisition process, but the structure of the functional template must be built up before parameter setting can begin. I adopt this hypothesis due to its compatibility with my finding that in the acquisition of Russian wh-questions, the functional projection CP appears at a later stage of syntactic development than other functional projections. Following Plunkett, I assume that in the beginning, the landing site for the wh-word is [Spec,TP] and later, for the valuation of other features (such as finiteness, the child is forced to acquire another functional projection (CP in order to create a landing site for the wh-word. The analysis shows that the first wh-questions acquired by the child are wh-complement questions. The child starts to produce subject wh-questions when the CP projection is acquired, and by the age of 2;4.14, the child’s structure of wh-questions is close to that of adult speech.

Semi-automated categorization of open-ended questions

Directory of Open Access Journals (Sweden)

Matthias Schonlau

2016-08-01

Full Text Available Text data from open-ended questions in surveys are difficult to analyze and are frequently ignored. Yet open-ended questions are important because they do not constrain respondents’ answer choices. Where open-ended questions are necessary, sometimes multiple human coders hand-code answers into one of several categories. At the same time, computer scientists have made impressive advances in text mining that may allow automation of such coding. Automated algorithms do not achieve an overall accuracy high enough to entirely replace humans. We categorize open-ended questions soliciting narrative responses using text mining for easy-to-categorize answers and humans for the remainder using expected accuracies to guide the choice of the threshold delineating between “easy” and “hard”. Employing multinomial boosting avoids the common practice of converting machine learning “confidence scores” into pseudo-probabilities. This approach is illustrated with examples from open-ended questions related to respondents’ advice to a patient in a hypothetical dilemma, a follow-up probe related to respondents’ perception of disclosure/privacy risk, and from a question on reasons for quitting smoking from a follow-up survey from the Ontario Smoker’s Helpline. Targeting 80% combined accuracy, we found that 54%-80% of the data could be categorized automatically in research surveys.

Emerging paradigms and questions on pro-angiogenic bone marrow-derived myelomonocytic cells.

Science.gov (United States)

Laurent, Julien; Touvrey, Cédric; Botta, Francesca; Kuonen, François; Ruegg, Curzio

2011-01-01

Cancer-related inflammation has emerged in recent years as a major event contributing to tumor angiogenesis, tumor progression and metastasis formation. Bone marrow-derived and inflammatory cells promote tumor angiogenesis by providing endothelial progenitor cells that differentiate into mature endothelial cells, and by secreting pro-angiogenic factors and remodeling the extracellular matrix to stimulate angiogenesis though paracrine mechanisms. Several bone marrow-derived myelonomocytic cells, including monocytes and macrophages, have been identified and characterized by several laboratories in recent years. While the central role of these cells in promoting tumor angiogenesis, tumor progression and metastasis is nowadays well established, many questions remain open and new ones are emerging. These include the relationship between their phenotype and function, the mechanisms of pro-angiogenic programming, their contribution to resistance to anti-angiogenic treatments and to metastasis and their potential clinical use as biomarkers of angiogenesis and anti-angiogenic therapies. Here, we will review phenotypical and functional aspects of bone marrow-derived myelonomocytic cells and discuss some of the current outstanding questions.

Gender differences in major depressive disorder : Results from the Netherlands study of depression and anxiety

NARCIS (Netherlands)

Schuch, Jerome J. J.; Roest, Annelieke M.; Nolen, Willem A.; Penninx, Brenda W. J. H.; de Jonge, Peter

Background: Although an overall gender difference in prevalence of major depressive disorder (MDD) has been well established, several questions concerning gender differences in the clinical manifestation of depression remain. This study aims to identify gender differences in psychopathology,

Two questions about surrogacy and exploitation.

Science.gov (United States)

Wertheimer, Alan

1992-01-01

In this article I will consider two related questions about surrogacy and exploitation: (1) Is surrogacy exploitative? (2) If surrogacy is exploitative, what is the moral force of this exploitation? Briefly stated, I shall argue that whether surrogacy is exploitative depends on whether exploitation must be harmful to the exploited party or whether (as I think) there can be mutually advantageous exploitation. It also depends on some facts about surrogacy about which we have little reliable evidence and on our philosophical view on what counts as a harm to the surrogate. Our answer to the second question will turn in part on the account of exploitation we invoke in answering the first question and in part on the way in which we resolve some other questions about the justification of state interference. I shall suggest, however, that if surrogacy is a form of voluntary and mutually advantageous exploitation, then there is a strong presumption that surrogacy contracts should be permitted and even enforceable, although that presumption may be overridden on other grounds.

Transforming classroom questioning using emerging technology.

Science.gov (United States)

Mahon, Paul; Lyng, Colette; Crotty, Yvonne; Farren, Margaret

2018-04-12

Classroom questioning is a common teaching and learning strategy in postgraduate nurse education. Technologies such as audience response systems (ARS) may offer advantage over traditional approaches to classroom questioning. However, despite being available since the 1960s, ARSs are still considered novel in many postgraduate nurse education classroom settings. This article aims to explicate the attitudes of postgraduate nursing students in an Irish academic teaching hospital towards classroom questioning (CQ) and the use of ARSs as an alternative to traditional CQ techniques. The results of this small-scale study demonstrate that ARSs have a role to play in CQ in the postgraduate setting, being regarded by students as beneficial to learning, psychological safety and classroom interaction.

Research priorities in mesothelioma: A James Lind Alliance Priority Setting Partnership.

Science.gov (United States)

Stephens, R J; Whiting, C; Cowan, K

2015-08-01

In the UK, despite the import and use of all forms of asbestos being banned more than 15 years ago, the incidence of mesothelioma continues to rise. Mesothelioma is almost invariably fatal, and more research is required, not only to find more effective treatments, but also to achieve an earlier diagnosis and improve palliative care. Following a debate in the House of Lords in July 2013, a package of measures was agreed, which included a James Lind Alliance Priority Setting Partnership, funded by the National Institute for Health Research. The partnership brought together patients, carers, health professionals and support organisations to agree the top 10 research priorities relating to the diagnosis, treatment and care of patients with mesothelioma. Following the established James Lind Alliance priority setting process, mesothelioma patients, current and bereaved carers, and health professionals were surveyed to elicit their concerns regarding diagnosis, treatment and care. Research questions were generated from the survey responses, and following checks that the questions were currently unanswered, an interim prioritisation survey was conducted to identify a shortlist of questions to take to a final consensus meeting. Four hundred and fifty-three initial surveys were returned, which were refined into 52 unique unanswered research questions. The interim prioritisation survey was completed by 202 responders, and the top 30 questions were taken to a final meeting where mesothelioma patients, carers, and health professionals prioritised all the questions, and reached a consensus on the top 10. The top 10 questions cover a wide portfolio of research (including assessing the value of immunotherapy, individualised chemotherapy, second-line treatment and immediate chemotherapy, monitoring patients with pleural thickening, defining the management of ascites in peritoneal mesothelioma, and optimising follow-up strategy). This list is an invaluable resource, which should be

Comparison of integrated testlet and constructed-response question formats

Directory of Open Access Journals (Sweden)

Aaron D. Slepkov

2014-09-01

Full Text Available Constructed-response (CR questions are a mainstay of introductory physics textbooks and exams. However, because of the time, cost, and scoring reliability constraints associated with this format, CR questions are being increasingly replaced by multiple-choice (MC questions in formal exams. The integrated testlet (IT is a recently developed question structure designed to provide a proxy of the pedagogical advantages of CR questions while procedurally functioning as set of MC questions. ITs utilize an answer-until-correct response format that provides immediate confirmatory or corrective feedback, and they thus allow not only for the granting of partial credit in cases of initially incorrect reasoning, but, furthermore, the ability to build cumulative question structures. Here, we report on a study that directly compares the functionality of ITs and CR questions in introductory physics exams. To do this, CR questions were converted to concept-equivalent ITs, and both sets of questions were deployed in midterm and final exams. We find that both question types provide adequate discrimination between stronger and weaker students, with CR questions discriminating slightly better than the ITs. There is some indication that any difference in discriminatory power may result from the baseline score for guessing that is inherent in MC testing. Meanwhile, an analysis of interrater scoring of the CR questions raises serious concerns about the reliability of the granting of partial credit when this traditional assessment technique is used in a realistic (but nonoptimized setting. Furthermore, we show evidence that partial credit is granted in a valid manner in the ITs. Thus, together with consideration of the vastly reduced costs of administering IT-based examinations compared to CR-based examinations, our findings indicate that ITs are viable replacements for CR questions in formal examinations where it is desirable both to assess concept integration and to

Interviewers' question rewording: not always a bad thing

NARCIS (Netherlands)

Haan, Marieke; Ongena, Yfke; Huiskes, Mike

2013-01-01

Although correct question reading is a fundamental assumption of standardized interviewing, in surveys, interviewers will not always read all questions exactly as worded. In this study the deviations in question reading by interviewers were analyzed. In addition, we studied if these deviations were

VERITAS: a Discovery-Class Venus Surface Geology and Geophysics Mission

Science.gov (United States)

Freeman, Anthony; Smrekar, Suzanne E.; Hensley, Scott; Wallace, Mark; Sotin, Christophe; Darrach, Murray; Xaypraseuth, Peter; Helbert, Joern; Mazarico, Erwan

2016-01-01

Our understanding of solar system evolution is limited by a great unanswered question: How Earthlike is Venus? We know that these "twin" planets formed with similar bulk composition and size. Yet the evolutionary path Venus followed has diverged from Earth's, in losing its surface water and becoming hotter than Mercury. What led to this? The answer has profound implications for how terrestrial planets become habitable and the potential for life in the universe.

Lightweight Portable Plasma Medical Device - Plasma Engineering Research Laboratory

Science.gov (United States)

2015-12-01

monocytic leukemia cancer cells ( THP -1) were also tested and the results 19 demonstrate that a preference for apoptosis in plasma treated THP -1...unanswered questions. We have tested the effects of indirect exposure of non-thermal air plasma on monocytic leukemia cancer cells ( THP -1) and deciphering... tested and the results are shown in Fig. above. The results demonstrate that a preference for apoptosis in plasma treated THP -1 cells under

Naval Medical Research and Development News. Volume 8, Issue 7, July 2016

Science.gov (United States)

2016-07-01

with the pathogen. The virus can be spread by infected people, contaminated food or water, or contact with contaminated surfaces, making...effectiveness to support approval by the U.S. Food and Drug Administration for widespread use among other U.S. military populations and civilians. NHRC has... Malaysia aims to address some of these unanswered questions. Led by Lt. Brian L. Pike of the Naval Medical Research Center – Asia (NMRC- A) based in

Poland: Lone Eagle over Europe

Science.gov (United States)

2012-05-17

found himself surrounded by enemies. To complicate matters, the Treaty of Versailles and the Paris Peace Conference left many unanswered questions...reported Russian forces 75 miles from Warsaw and laying siege to the fortresses of Lomza and Brest -Litovsk along the Bug River.80 Like Pilsudski’s drive...territories granted by the Treaty of Versailles and the Paris Peace Conference.124 With the possibility of war, the Poles turned their nation’s military

Periprosthetic Joint Infections: Clinical and Bench Research

Directory of Open Access Journals (Sweden)

Laurence Legout

2013-01-01

Full Text Available Prosthetic joint infection is a devastating complication with high morbidity and substantial cost. The incidence is low but probably underestimated. Despite a significant basic and clinical research in this field, many questions concerning the definition of prosthetic infection as well the diagnosis and the management of these infections remained unanswered. We review the current literature about the new diagnostic methods, the management and the prevention of prosthetic joint infections.

Does First Last: The Existence and Extent of First Mover Advantages on Spatial Networks

OpenAIRE

David Levinson; Feng Xie

2007-01-01

This paper examines the nature of first mover advantages on spatially-differentiated surface transportation networks. The literature on first mover advantages identifies a number of sources that explain their existence. However whether those sources exist on spatial networks, and how they play out with true capital immobility have been unanswered questions. By examining empirical examples including commuter rail and the Underground in London and roads in the Twin Cities of Minneapolis and St....

Patient Mobility in the Global Marketplace: A Multidisciplinary Perspective

Directory of Open Access Journals (Sweden)

Neil Lunt

2014-05-01

Full Text Available There is a growing global market in healthcare and patients. And while there is a small body of evidence emerging around this phenomenon commonly known as medical tourism there remain significant unanswered policy and research questions which need to be addressed. We outline some of the key issues set against the six key disciplinary preoccupations of the journal: epidemiology, health economics, health policy ethics, politics of health, health management, and health policy.

Opening the door to innovation in cloud computing

OpenAIRE

Clohessy, Trevor; Acton, Thomas

2013-01-01

peer-reviewed This paper describes research-in-progress that explores the applicability and implications of cloud computing in the creation of business value through open innovation. Both the cloud computing and open innovation paradigms represent recent phenomenon and as such many unanswered questions still persist. In responding to this research gap we propose a new value creation framework which is based on a review of the literature on cloud computing, innovation, open innovation and v...

Providing a Theoretical Basis for Nanotoxicity Risk Analysis Departing from Traditional Physiologically-Based Pharmacokinetic (PBPK) Modeling

Science.gov (United States)

2010-09-01

studies has left many unanswered questions, including one posed by Riviere and Tran in their article on pharmacokinetics of nanomaterials which asks...layer of thick mucus . Particles smaller than 10 m can reach the gas exchange surfaces (alveoli), where Brownian motion leads to deposition [8]. Very...breast milk are other possible means of secreting toxicants [34], but are 10 not included in this dissertation. 2.1.2 Organs of Concern. 2.1.2.1

Probability and Statistics: 5 Questions

DEFF Research Database (Denmark)

Probability and Statistics: 5 Questions is a collection of short interviews based on 5 questions presented to some of the most influential and prominent scholars in probability and statistics. We hear their views on the fields, aims, scopes, the future direction of research and how their work fits...... in these respects. Interviews with Nick Bingham, Luc Bovens, Terrence L. Fine, Haim Gaifman, Donald Gillies, James Hawthorne, Carl Hoefer, James M. Joyce, Joseph B. Kadane Isaac Levi, D.H. Mellor, Patrick Suppes, Jan von Plato, Carl Wagner, Sandy Zabell...

Recent progress in understanding of the ion composition in the magnetosphere and some major question mark

International Nuclear Information System (INIS)

Hultqvist, B.

1981-06-01

The observations of the energetic ion composition in the magnetosphere are reviewed with the emphasis on the recent measurements by means of GEOS-1 and -2, ISEE-1 and 2, PROGNOZ-7 and SCATHA. The observations are compared with the predictions of the open magnetosphere model. One of the major conclusions is that there are processes in the magnetosphere which play a much larger part than the model, as hitherto presented, predicts. Direct ejection of ionospheric ions, in combination with acceleration, along closed as well as open field lines may even be the dominating source process for the ring current/inner plasma sheet in magnetic storms. In very disturbed conditions this ejection mechanism must work over most of the hemispheres poleward of say 50degrees. Circulation of the ionospheric ions through the tail of the magnetosphere is not likely to be of primary importance for the energization of these ions in very disturbed conditions. (author)

Accuracy of questions related to allergic contact dermatitis.

Science.gov (United States)

Fleming, C J; Burden, A D; Forsyth, A

2000-12-01

The ability of a physician to select individuals likely to benefit from patch testing depends on his or her ability to interpret responses to enquiries related to contact allergy. The significance of such responses to questions of nickel, fragrance and colophon allergy is unclear. The specificity, sensitivity and predictive value of questions relating to nickel, fragrance and colophony allergy were determined. A total of 258 patients attending for routine patch testing were questioned about skin reactions to nickel, fragrances and Elastoplast (Smith and Nephew Healthcare, Hull, England). All subjects were then patch tested to nickel, fragrance mix, and colophony. Responses to questions were compared with patch test results. The sensitivity of questions relating to nickel, fragrance, and colophony was 82%, 49%, and 71%, respectively. The specificity of the same questions was 77%, 79%, and 90%; the positive predictive value was 54%, 46% and 29%, respectively. After adjustment to include clinical relevance, the sensitivity of nickel questions rose to 100%. These data permit greater understanding of the role of patient history in selection of patients for patch testing. Copyright 2000 by W.B. Saunders Company

Children's Question Asking and Curiosity: A Training Study

Science.gov (United States)

Jirout, Jamie; Klahr, David

2011-01-01

A primary instructional objective of most early science programs is to foster children's scientific curiosity and question-asking skills (Jirout & Klahr, 2011). However, little is known about the relationship between curiosity, question-asking behavior, and general inquiry skills. While curiosity and question asking are invariably mentioned in…

D-linking or set-restriction? Processing Which-questions in Dutch

NARCIS (Netherlands)

Donkers, Jantien; Hoeks, John C. J.; Stowe, Laurie A.

2013-01-01

Research on Wh-questions suggests that Which questions are harder to process than Who questions (e.g., Who/Which athlete won the competition?). According to the Discourse (D)-linking Hypothesis, Which-questions differ from Who-questions in that Which questions need a link to a preceding discourse,

[Ethical questions in the Spanish journal "Medicina Paliativa": 1994 - 2013].

Science.gov (United States)

Sanz Rubiales, Alvaro; Del Valle Rivero, María Luisa; Flores Pérez, Luis Alberto; Hernansanz de la Calle, Silvia; Gutiérrez Alonso, Celia; García Recio, Consuelo

2014-01-01

"Medicina Paliativa" is the official journal of the Spanish Society of Palliative Care ("Sociedad Española de Cuidados Paliativos"; SECPAL) and it reflects the interests, also on bioethics, of the professionals caring terminal people. We want to know what the bioethical questions they discuss and their approaches are. From all the published articles in "Medicina Paliativa" from 1994 to 2013 we selected those referred to bioethics topics. We analysed: number of publications, author, subtype of article, year of publication, topic, philosophic approach, and the presence of answers and discussion. Qualitative topics were reviewed and agreed by at least two authors. There were 60 (9%) publications with bioethics profile from a total of 672 analyzed articles. A majority were signed by only one author. 31 (51%) were published as letter. The most relevant topics were: euthanasia, dignity, proportionality of treatment and care, sedation, principles of bioethics, and information. The orientation of these papers was, in a majority, according to principles of palliative care. Most bioethics topics have been answered and even answered back. Bioethics is an interesting topic in palliative care. The arguments usually fit the principles of palliative care.

The "wh" questions of visual phonics: what, who, where, when, and why.

Science.gov (United States)

Narr, Rachel F; Cawthon, Stephanie W

2011-01-01

Visual Phonics is a reading instructional tool that has been implemented in isolated classrooms for over 20 years. In the past 5 years, several experimental studies demonstrated its efficacy with students who are deaf or hard of hearing. Through a national survey with 200 participants, this study specifically addresses who, where, how, and why a sample of teachers use Visual Phonics in their everyday reading instruction. Through checklists of teaching practice, rating scales, and open-ended questions, teachers self-reported their use of Visual Phonics, reflected upon its efficacy, and what they think about using it with students with a diverse set of instructional needs. The majority reported that Visual Phonics was easy to use, engaging to students, and easy to integrate into a structured reading curriculum. The majority of respondents agreed that it helps increase phonemic awareness and decoding skills, build vocabulary, as well as increase reading comprehension. The implications of these findings in bridging the research-to-practice gap are discussed.

Persistence among Minority STEM Majors: A Phenomenological Study

Science.gov (United States)

Williams-Watson, Stacey

The United States needs to increase the number of science, technology, engineering, and math (STEM) graduates to remain competitive in the global market and maintain national security. Minority students, specifically African-American and Hispanic, are underrepresented in STEM fields. As the minority population continues to grow it is essential that higher education institutions improve minority students' persistence in STEM education. This study examined the problem of minority students' lack of persistence in STEM programs. The purpose of this qualitative transcendental phenomenological study was to describe the lived experiences that minority students perceived as contributing to their persistence in STEM. The central research question was: What are the lived experiences of minority STEM students that have contributed to their persistence in a STEM program? The sub-questions were: a) What led participants to majors in STEM?; b) What contributed to students' success and persistence in STEM?; and c) What advice do students have to offer? The researcher interviewed 12 minority STEM students and uncovered 10 themes that described the lived experiences of minority students' persistence in STEM programs. The themes were 1) Childhood experiences and interests; 2) Positive educational experiences in secondary school; 3) Self- motivation; 4) Positive experiences with professors; 5) Family encouragement and values; 6) Lack of minorities; 7) Lack of educational preparation; 8) The need for financial assistance; 9) Clubs and organizations; and 10) Friends within the major. The significance of these findings is the potential to produce changes in curricula, programs, and retention methods that may improve the persistence of minority students in STEM programs.

Cellular Cholesterol Directly Activates Smoothened in Hedgehog Signaling

Energy Technology Data Exchange (ETDEWEB)

Huang, Pengxiang; Nedelcu, Daniel; Watanabe, Miyako; Jao, Cindy; Kim, Youngchang; Liu, Jing; Salic, Adrian

2016-08-01

In vertebrates, sterols are necessary for Hedgehog signaling, a pathway critical in embryogenesis and cancer. Sterols activate the membrane protein Smoothened by binding its extracellular, cysteine-rich domain (CRD). Major unanswered questions concern the nature of the endogenous, activating sterol and the mechanism by which it regulates Smoothened. We report crystal structures of CRD complexed with sterols and alone, revealing that sterols induce a dramatic conformational change of the binding site, which is sufficient for Smoothened activation and is unique among CRD-containing receptors. We demonstrate that Hedgehog signaling requires sterol binding to Smoothened and define key residues for sterol recognition and activity. We also show that cholesterol itself binds and activates Smoothened. Furthermore, the effect of oxysterols is abolished in Smoothened mutants that retain activation by cholesterol and Hedgehog. We propose that the endogenous Smoothened activator is cholesterol, not oxysterols, and that vertebrate Hedgehog signaling controls Smoothened by regulating its access to cholesterol.

Emissions of biogenic sulfur gases from northern bogs and fens

Science.gov (United States)

Demello, William Zamboni; Hines, Mark E.; Bayley, Suzanne E.

1992-01-01

Sulfur gases are important components of the global cycle of S. They contribute to the acidity of precipitation and they influence global radiation balance and climate. The role of terrestrial sources of biogenic S and their effect on atmospheric chemistry remain as major unanswered questions in our understanding of the natural S cycle. The role of northern wetlands as sources and sinks of gaseous S by measuring rates of S gas exchange as a function of season, hydrologic conditions, and gradients in tropic status was investigated. Experiments were conducted in wetlands in New Hampshire, particularly a poor fen, and in Mire 239, a poor fen at the Experimental Lakes Area (ELA) in Ontario. Emissions were determined using Teflon enclosures, gas cryotrapping methods and gas chromatography (GC) with flame photometric detection. Dynamic (sweep flow) and static enclosures were employed which yielded similar results. Dissolved S gases and methane were determined by gas stripping followed by GC.

Explosive mutation accumulation triggered by heterozygous human Pol ε proofreading-deficiency is driven by suppression of mismatch repair

Science.gov (United States)

Campbell, Brittany B; Ungerleider, Nathan; Light, Nicholas; Wu, Tong; LeCompte, Kimberly G; Goksenin, A Yasemin; Bunnell, Bruce A; Tabori, Uri; Shlien, Adam

2018-01-01

Tumors defective for DNA polymerase (Pol) ε proofreading have the highest tumor mutation burden identified. A major unanswered question is whether loss of Pol ε proofreading by itself is sufficient to drive this mutagenesis, or whether additional factors are necessary. To address this, we used a combination of next generation sequencing and in vitro biochemistry on human cell lines engineered to have defects in Pol ε proofreading and mismatch repair. Absent mismatch repair, monoallelic Pol ε proofreading deficiency caused a rapid increase in a unique mutation signature, similar to that observed in tumors from patients with biallelic mismatch repair deficiency and heterozygous Pol ε mutations. Restoring mismatch repair was sufficient to suppress the explosive mutation accumulation. These results strongly suggest that concomitant suppression of mismatch repair, a hallmark of colorectal and other aggressive cancers, is a critical force for driving the explosive mutagenesis seen in tumors expressing exonuclease-deficient Pol ε. PMID:29488881

A Dysregulated Endocannabinoid-Eicosanoid Network Supports Pathogenesis in a Mouse Model of Alzheimer's Disease

Directory of Open Access Journals (Sweden)

Justin R. Piro

2012-06-01

Full Text Available Although inflammation in the brain is meant as a defense mechanism against neurotoxic stimuli, increasing evidence suggests that uncontrolled, chronic, and persistent inflammation contributes to neurodegeneration. Most neurodegenerative diseases have now been associated with chronic inflammation, including Alzheimer's disease (AD. Whether anti-inflammatory approaches can be used to treat AD, however, is a major unanswered question. We recently demonstrated that monoacylglycerol lipase (MAGL hydrolyzes endocannabinoids to generate the primary arachidonic acid pool for neuroinflammatory prostaglandins. In this study, we show that genetic inactivation of MAGL attenuates neuroinflammation and lowers amyloid β levels and plaques in an AD mouse model. We also find that pharmacological blockade of MAGL recapitulates the cytokine-lowering effects through reduced prostaglandin production, rather than enhanced endocannabinoid signaling. Our findings thus reveal a role of MAGL in modulating neuroinflammation and amyloidosis in AD etiology and put forth MAGL inhibitors as a potential next-generation strategy for combating AD.

The roles of amensalistic and commensalistic interactions in large ecological network stability.

Science.gov (United States)

Mougi, Akihiko

2016-07-13

Ecological communities comprise diverse species and their interactions. Notably, ecological and evolutionary studies have revealed that reciprocal interactions such as predator-prey, competition, and mutualism, are key drivers of community dynamics. However, there is an argument that many species interactions are asymmetric, where one species unilaterally affects another species (amensalism or commensalism). This raises the unanswered question of what is the role of unilateral interactions in community dynamics. Here I use a theoretical approach to demonstrate that unilateral interactions greatly enhance community stability. The results suggested that amensalism and commensalism were more stabilizing than symmetrical interactions, such as competition and mutualism, but they were less stabilizing than an asymmetric antagonistic interaction. A mix of unilateral interactions increased stability. Furthermore, in communities with all interaction types, unilateral interactions tended to increase stability. This study suggests that unilateral interactions play a major role in maintaining communities, underlining the need to further investigate their roles in ecosystem dynamics.

Floral advertisement and the competition for pollination services.

Science.gov (United States)

Fishman, Michael A; Hadany, Lilach

2015-06-01

Flowering plants are a major component of terrestrial ecosystems, and most of them depend on animal pollinators for reproduction. Thus, the mutualism between flowering plants and their pollinators is a keystone ecological relationship in both natural and agricultural ecosystems. Though plant-pollinator interactions have received considerable amount of attention, there are still many unanswered questions. In this paper, we use methods of evolutionary game theory to investigate the co-evolution of floral advertisement and pollinator preferences Our results indicate that competition for pollination services among plant species can in some cases lead to specialization of the pollinator population to a single plant species (oligolecty). However, collecting pollen from multiple plants - at least at the population level - is evolutionarily stable under a wider parameter range. Finally, we show that, in the presence of pollinators, plants that optimize their investment in attracting vs. rewarding visiting pollinators outcompete plants that do not. Copyright © 2015 Elsevier Ireland Ltd. All rights reserved.

Question-asking behavior as a form of cognitive activity

Directory of Open Access Journals (Sweden)

Elvira A. Baranova

2017-03-01

Full Text Available Children’s questions are an indicator of active cognitive perception of reality. Questions but not answers are relevant in revealing a child’s mental life, consciousness and thinking. The lack of question-asking skills can hinder learning, searching and exploration in children. To determine in 7- and 8-year-old school children the common and variable peculiarities of designing a search process for necessary information concerning an unknown object by volitionally formulated questions, as well as the dynamics of the questioning process throughout a school year. The study was based on an experimental methodology, codenamed Guess what there is in the box, and was conducted in four schools in Cheboksary. The sample comprised 158 primary school first-graders who took part in a confirmatory experiment twice, once in September and once in May. The research showed that 96.3% of the questions asked were search questions. Only 30% of the first-graders initiated their searching activities of their own will without having to resort to the given search algorithm, while 70% did not begin asking questions without outside stimulation. The analysis of the dynamics of children’s question-asking behavior exhibited a tendency to decrease in a number of questions asked over the course of the school year. Primary school children need psychological and pedagogical scaffolding aimed at developing a question-asking behavior as a form of cognitive activity to achieve a possible age potential in development.

The role of teacher questions in the chemistry classroom

DEFF Research Database (Denmark)

Dohrn, Sofie Weiss; Dohn, Niels Bonderup

2018-01-01

, the students become highly accomplished in recalling facts but have difficulties when higher order thinking is required. The findings suggest that an interactive classroom can be created by using many engaging teacher questions. The six different categories of questions promote the students' learning process......The purpose of this study was to investigate how a chemistry teacher's questions influence the classroom discourse. It presents a fine-grained analysis of the rich variety of one teacher's questions and the roles they play in an upper secondary chemistry classroom. The study identifies six...... different functions for the teacher's questions: Student Knowledge, Request, Monologic Discourse, Clarification, Relations and Interaction of Contexts. Overall, these questions create a safe and interactive learning environment. However, the questions are predominantly closed in form. As a result...

Quorum sensing: a quantum perspective.

Science.gov (United States)

Majumdar, Sarangam; Pal, Sukla

2016-09-01

Quorum sensing is the efficient mode of communication in the bacterial world. After a lot of advancements in the classical theory of quorum sensing few basic questions of quorum sensing still remain unanswered. The sufficient progresses in quantum biology demands to explain these questions from the quantum perspective as non trivial quantum effects already have manifested in various biological processes like photosynthesis, magneto-reception etc. Therefore, it's the time to review the bacterial communications from the quantum view point. In this article we carefully accumulate the latest results and arguments to strengthen quantum biology through the addition of quorum sensing mechanism in the light of quantum mechanics.

Predicting how nanoconfinement changes the relaxation time of a supercooled liquid.

Science.gov (United States)

Ingebrigtsen, Trond S; Errington, Jeffrey R; Truskett, Thomas M; Dyre, Jeppe C

2013-12-06

The properties of nanoconfined fluids can be strikingly different from those of bulk liquids. A basic unanswered question is whether the equilibrium and dynamic consequences of confinement are related to each other in a simple way. We study this question by simulation of a liquid comprising asymmetric dumbbell-shaped molecules, which can be deeply supercooled without crystallizing. We find that the dimensionless structural relaxation times-spanning six decades as a function of temperature, density, and degree of confinement-collapse when plotted versus excess entropy. The data also collapse when plotted versus excess isochoric heat capacity, a behavior consistent with the existence of isomorphs in the bulk and confined states.

How can we not 'lose it' if we still don't understand how to 'use it'? Unanswered questions about the influence of activity participation on cognitive performance in older age--a mini-review.

Science.gov (United States)

Bielak, Allison A M

2010-01-01

The 'use it or lose it' hypothesis of cognitive aging predicts that engagement in intellectual, social, and physical activities offers protective benefits from age-related cognitive decline and lowers dementia risk. Although this hypothesis has not yet been supported conclusively, there is some empirical evidence in favor of the proposal. However, a number of questions surrounding the relationship between activity participation and cognitive ability in older adulthood are not yet well answered. This mini-review identifies seven key methodological and theoretical issues that are critical to our understanding and eventual possible promotion of activity participation as a way to maintain cognitive well-being. These include the mechanisms involved, the optimal ways of assessing activity engagement, which cognitive domains receive the most benefit from activity engagement, the temporal nature and the directionality of the relationship, the influence of demographic variables such as age, gender, or education, and whether one activity domain offers the most benefit to cognition. The current knowledge on each of these issues is critically evaluated, including describing what we already know about the issue, and identifying potential difficulties and opportunities that may exist in finding an answer. More studies need to take on the challenge of specifically targeting these issues, as each is essential to moving the field forward. Copyright (c) 2009 S. Karger AG, Basel.

Sex segregation in undergraduate engineering majors

Science.gov (United States)

Litzler, Elizabeth

Gender inequality in engineering persists in spite of women reaching parity in college enrollments and degrees granted. To date, no analyses of educational sex segregation have comprehensively examined segregation within one discipline. To move beyond traditional methods of studying the long-standing stratification by field of study in higher education, I explore gender stratification within one field: engineering. This dissertation investigates why some engineering disciplines have a greater representation of women than other engineering disciplines. I assess the individual and institutional factors and conditions associated with women's representation in certain engineering departments and compare the mechanisms affecting women's and men's choice of majors. I use national data from the Engineering Workforce Commission, survey data from 21 schools in the Project to Assess Climate in Engineering study, and Carnegie Foundation classification information to study sex segregation in engineering majors from multiple perspectives: the individual, major, institution, and country. I utilize correlations, t-tests, cross-tabulations, log-linear modeling, multilevel logistic regression and weighted least squares regression to test the relative utility of alternative explanations for women's disproportionate representation across engineering majors. As a whole, the analyses illustrate the importance of context and environment for women's representation in engineering majors. Hypotheses regarding hostile climate and discrimination find wide support across different analyses, suggesting that women's under-representation in certain engineering majors is not a question of choice or ability. However, individual level factors such as having engineering coursework prior to college show an especially strong association with student choice of major. Overall, the analyses indicate that institutions matter, albeit less for women, and women's under-representation in engineering is not

Usage-Based vs. Rule-Based Learning: The Acquisition of Word Order in "Wh"-Questions in English and Norwegian

Science.gov (United States)

Westergaard, Marit

2009-01-01

This paper discusses different approaches to language acquisition in relation to children's acquisition of word order in "wh"-questions in English and Norwegian. While generative models assert that children set major word order parameters and thus acquire a rule of subject-auxiliary inversion or generalized verb second (V2) at an early stage, some…

QUESTION FORMATION OF BAHASA INDONESIA AS A SECOND LANGUAGE

Directory of Open Access Journals (Sweden)

zulfa Sakhiyya

2013-07-01

Full Text Available Abstract: This article aims to implement Processability Theory (PT to Bahasa Indonesia or Indonesian language and to identify developmental stages for question formation in the setting of Bahasa Indonesia as a second language (ISL. PT provides a theoretical framework in making predictions about the course of language development, in this case the question formation acquisition. This study proposes developmental stages of question formation in ISL setting by contrasting the lexical functional grammar of Indonesian question as compared to ESL question formation. Four stages of ISL question formation were proposed. The proposed stages serve as the basis for data analysis and to show its plausibility.

Can we build a more efficient airplane? Using applied questions to teach physics

Science.gov (United States)

Bhatia, Aatish

2014-03-01

For students and for the science-interested public, applied questions can serve as a hook to learn introductory physics. Can we radically improve the energy efficiency of modern day aircraft? Are solar planes like the Solar Impulse the future of travel? How do migratory birds like the alpine swift fly nonstop for nearly seven months? Using examples from aeronautical engineering and biology, I'll discuss how undergraduate physics can shed light on these questions about transport, and place fundamental constraints on the flight properties of flying machines, whether birds or planes. Education research has shown that learners are likely to forget vast content knowledge unless they get to apply this knowledge to novel and unfamiliar situations. By applying physics to real-life problems, students can learn to build and apply quantitative models, making use of skills such as order of magnitude estimates, dimensional analysis, and reasoning about uncertainty. This applied skillset allows students to transfer their knowledge outside the classroom, and helps build connections between traditionally distinct content areas. I'll also describe the results of an education experiment at Rutgers University where my colleagues and I redesigned a 100+ student introductory physics course for social science and humanities majors to address applied questions such as evaluating the energy cost of transport, and asking whether the United States could obtain all its energy from renewable sources.

On the placement of practice questions during study.

Science.gov (United States)

Weinstein, Yana; Nunes, Ludmila D; Karpicke, Jeffrey D

2016-03-01

Retrieval practice improves retention of information on later tests. A question remains: When should retrieval occur during learning-interspersed throughout study or at the end of each study period? In a lab experiment, an online experiment, and a classroom study, we aimed to determine the ideal placement (interspersed vs. at-the-end) of retrieval practice questions. In the lab experiment, 64 subjects viewed slides about APA style and answered short-answer practice questions about the content or restudied the slides (restudy condition). The practice questions either appeared 1 every 1-2 slides (interspersed condition), or all at the end of the presentation (at-the-end condition). One week later, subjects returned and answered the same questions on a final test. In the online experiment, 175 subjects completed the same procedure. In the classroom study, 62 undergraduate students took quizzes as part of class lectures. Short-answer practice questions appeared either throughout the lectures (interspersed condition) or at the end of the lectures (at-the-end condition). Nineteen days after the last quiz, students were given a surprise final test. Results from the 3 experiments converge in demonstrating an advantage for interspersing practice questions on the initial tests, but an absence of this advantage on the final test. (c) 2016 APA, all rights reserved).

Radiation protection in questions and answers

International Nuclear Information System (INIS)

Ewen, K.; Hoppe, G.

1976-01-01

An easily surveyable catalogue of questions is presented which is to make it easier for medical personnel to get acquainted with the basic knowledge according to the X-ray Ordinance and to acquire the expert knowledge in radiation protection. The catalogue is arranged according to different subjects. There are several alternative answers to every question. The right answer is given in the solution index (annex). (HP) [de

The implications of nonauthentic questions in Galatians | Verster ...

African Journals Online (AJOL)

A new classification of non-authentic questions is helpful in understanding the way in which Paul uses persuasion in Galatians. Paul uses many non-authentic questions, and the implications thereof are evident in the type of question used. The way in which he violates the maxims identified by Grice also entails certain ...

Questions about elastic waves

CERN Document Server

Engelbrecht, Jüri

2015-01-01

This book addresses the modelling of mechanical waves by asking the right questions about them and trying to find suitable answers. The questions follow the analytical sequence from elementary understandings to complicated cases, following a step-by-step path towards increased knowledge. The focus is on waves in elastic solids, although some examples also concern non-conservative cases for the sake of completeness. Special attention is paid to the understanding of the influence of microstructure, nonlinearity and internal variables in continua. With the help of many mathematical models for describing waves, physical phenomena concerning wave dispersion, nonlinear effects, emergence of solitary waves, scales and hierarchies of waves as well as the governing physical parameters are analysed. Also, the energy balance in waves and non-conservative models with energy influx are discussed. Finally, all answers are interwoven into the canvas of complexity.

Remittances as aid following major sudden-onset natural disasters.

Science.gov (United States)

Bragg, Catherine; Gibson, Glenn; King, Haleigh; Lefler, Ashley A; Ntoubandi, Faustin

2018-01-01

There is a general assumption, based on macroeconomic studies, that remittances will rise following major sudden-onset natural disasters. This is confirmed by a few assessments involving country-specific research, and usually short-term data. This study, questioning conventional wisdom, reviewed and graphed annual and quarterly remittance flows using International Monetary Fund and World Bank data from 2000-14 for 12 countries that confronted 18 major natural disasters. It found that, regardless of event type, annual remittances rose steadily from 2000-14 except for after the 2008-09 financial crisis. Post disaster, there was a quarterly increase in the majority of cases (confirming previous research) but there was seldom an annual increase in the year of the disaster greater than the average annual increase in 2000-14. It appears that remittance senders rush to provide assistance after a natural disaster, but since their own financial situation has not changed, the immediate increase is compensated by a later decrease. © 2018 The Author(s). Disasters © Overseas Development Institute, 2018.

Rabies: Questions and Answers

Science.gov (United States)

Rabies: Questions and Answers Information about the disease and vaccines What causes rabies? Rabies is caused by a virus. The virus invades ... nervous system and disrupts its functioning. How does rabies spread? The rabies virus is transmitted in the ...

A Survey Study of Autonomous Learning by Chinese Non-English Major Post-Graduates

Science.gov (United States)

Xu, Jianping

2009-01-01

This thesis reports a survey study of the autonomous L2 learning by 100 first-year non-English-major Chinese post-graduates via the instruments of a questionnaire and semi-structured interview after the questionnaire. It attends to address the following research question: To what extent do Chinese postgraduate students conduct autonomous L2…

Categorization of questions posed before and after inquiry-based learning

Directory of Open Access Journals (Sweden)

Sandra Milena García González

2014-07-01

Full Text Available Posing research questions is the central ability of the scientific thought. This article examines the ability of sixth grade children to pose researchable questions before and after a three months’ work on a didactic sequence based on the inquiry school model. According to their purpose, the questions asked by children, after reading a text, were classified into researchable questions -susceptible to be empirically explored-, questions about a cause, and questions on a piece of data. The results show that the amount and the type of questions the students were able to pose during the intervention changed, from most of questions on data or information, to most of researchable questions, subsequently, the importance of designing teaching approaches to foster this ability was proved.

Questioning Strategies of Literature Teachers among Grade 8 Filipino Students

Directory of Open Access Journals (Sweden)

Magdalena M. Ocbian

2015-11-01

Full Text Available Questioning is a useful and relevant tool to facilitate classroom discussion in a literature class. This study identified the levels of questions teachers use in their literature class, determined the different question strategies they utilized and proposed activities to enhance the questioning strategies of literature teachers. Video analysis was the main instrument used. These videos were provided during the conduct of class observations by the researchers. There were eight respondents in the study selected through total enumeration. They are teachers from Gubat Cluster of secondary schools of Sorsogon Province. To identify the levels of questions and questioning strategies, question tally form and percentage were used. Results revealed that knowledge was the most used level of questions followed by comprehension, application, analysis, synthesis and evaluation. The most used question technique is the participation, followed by proving, sequencing, wait time, balance and student questions. It was recommended that literature teachers vary their level of questions when discussing literary pieces. They may utilize different question techniques to develop critical thinking skills of their students. The use of the proposed activities may enhance the questioning strategies of literature teachers. Likewise, school heads and program supervisors may utilize video analysis technique as a mode for classroom observation.

More spinoff from spin

International Nuclear Information System (INIS)

Masaike, Akira

1993-01-01

Despite playing a major role in today's Standard Model, spin - the intrinsic angular momentum carried by particles - is sometimes dismissed as an inessential complication. However several major spin questions with important implications for the Standard Model remain unanswered, and recent results and new technological developments made the 10th International Symposium on High Energy Spin Physics, held in Nagoya, Japan, in November, highly topical. The symposium covered a wide range of physics, reflecting the diversity of spin effects, however four main themes were - the spin content of the nucleon, tests of symmetries and physics beyond standard models, intermediate energy physics, and spin technologies. Opening the meeting, T. Kinoshita reviewed the status of measurements of the anomalous magnetic moment (g-2) of the electron and the muon. The forthcoming experiment at Brookhaven (September 1991, page 23) will probe beyond the energy ranges open to existing electronpositron colliders. For example muon substructure will be opened up to 5 TeV and Ws to 2 TeV. R.L. Jaffe classified quark-parton distributions in terms of their spin dependence, pointing out their leftright attributes, and emphasized the importance of measuring transverse spin distributions through lepton pair production

Children's Exhaustive Readings of Questions

Science.gov (United States)

Cremers, Alexandre; Tieu, Lyn; Chemla, Emmanuel

2017-01-01

Questions, just like plain declarative sentences, can give rise to multiple interpretations. As discussed by Spector & Egré (2015), among others, questions embedded under know are ambiguous between "weakly exhaustive" (WE), "intermediate exhaustive" (IE), and "strongly exhaustive" (SE) interpretations (for…

Altered neural processing of reward and punishment in adolescents with Major Depressive Disorder.

Science.gov (United States)

Landes, I; Bakos, S; Kohls, G; Bartling, J; Schulte-Körne, G; Greimel, E

2018-05-01

Altered reward and punishment function has been suggested as an important vulnerability factor for the development of Major Depressive Disorder (MDD). Prior ERP studies found evidence for neurophysiological dysfunctions in reinforcement processes in adults with MDD. To date, only few ERP studies have examined the neural underpinnings of reinforcement processing in adolescents diagnosed with MDD. The present event-related potential (ERP) study aimed to investigate neurophysiological mechanisms of anticipation and consumption of reward and punishment in adolescents with MDD in one comprehensive paradigm. During ERP recording, 25 adolescents with MDD and 29 healthy controls (12-17 years) completed a Monetary Incentive Delay Task comprising both a monetary reward and a monetary punishment condition. During anticipation, the cue-P3 signaling attentional allocation was recorded. During consumption, the feedback-P3 and Reward Positivity (RewP) were recorded to capture attentional allocation and outcome evaluation, respectively. Compared to controls, adolescents with MDD showed prolonged cue-P3 latencies to reward cues. Furthermore, unlike controls, adolescents with MDD displayed shorter feedback-P3 latencies in the reward versus punishment condition. RewPs did not differ between groups. It remains unanswered whether the observed alterations in adolescent MDD represent a state or trait. Delayed neural processing of reward cues corresponds to the clinical presentation of adolescent MDD with reduced motivational tendencies to obtain rewards. Relatively shorter feedback-P3 latencies in the reward versus punishment condition could indicate a high salience of performance-contingent reward. Frequent exposure of negatively biased adolescents with MDD to performance-contingent rewards might constitute a promising intervention approach. Copyright © 2018 Elsevier B.V. All rights reserved.

Sample Focus Group Questions for Girls in STEM

Energy Technology Data Exchange (ETDEWEB)

Coronado, Elizabeth Phillips [Los Alamos National Lab. (LANL), Los Alamos, NM (United States)

2018-02-13

These are sample questions for focus groups to be conducted as part of qualitative data collection for Year 2- Year 6 of Girls in STEM. You may use any of the questions from the list during the two sessions during the school year, as long as those questions are not repeated in both Baseline and follow-up sessions.

The kinds of questions asked by novice teachers in learning mathematics

Science.gov (United States)

Zahra, L.; Kusmayadi, T. A.; Usodo, B.

2018-05-01

This study describes the kinds of questions asked by novice teachers during mathematics learning process in senior high school. This study used descriptive analysis. The subjects of this study were two novice teachers who teach mathematics in 10th grade. The result showed that the frequently asked questions by novice teachers based on the objective were compliance questions, rethorical questions and sometimes prompting questions and probing questions. The frequently questions asked by novice teacher based on the cognitive process dimension of Revised Bloom’s Taxonomy were questions of remembering, questions of understanding, questions of applying, questions of analyzing and questions of evaluating. The novice teachers asked the routine questions which had same thinking level. The question with the highest level of thinking did not asked by the novice teachers.

Questions and Answers about Sex (For Parents)

Science.gov (United States)

... español Preguntas y respuestas sobre sexo Answering their kids' questions about sex is a responsibility that many parents dread. Otherwise ... avoided. Parents can help foster healthy feelings about sex if they answer kids' questions in an age-appropriate way. When do ...

Question presentation methods for paired-associate learning

NARCIS (Netherlands)

Engel, F.L.; Geerings, M.P.W.

1988-01-01

Four different methods of question presentation, in interactive computeraided learning of Dutch-English word pairs are evaluated experimentally. These methods are: 1) the 'open-question method', 2) the 'multiple-choice method', 3) the 'sequential method' and 4) the 'true/ false method'. When

[Two simple questions to diagnose post-stroke depression].

Science.gov (United States)

Nolte, C H; Müller-Nordhorn, J; Jungehülsing, G J; Rossnagel, K; Reich, A; Roll, S; Laumeier, I; Beerfelde, D; Willich, S N; Villringer, A

2006-05-01

Many patients develop a depression after having suffered a stroke. Such a Post-Stroke Depression (PSD) impairs rehabilitation and quality of life. PSD is underdiagnosed in spite of available treatment. Several questionnaires have been created to diagnose a PSD. But questionnaires have been considered cumbersome and time-consuming. The aim of this study was to find out whether two simple, standardised questions will identify those stroke patients, who have developed a PSD. The two case-finding questions and the Beck Depression Inventory (BDI) were sent to patients of the Berlin Acute Stroke Study (BASS) four years after their stroke. Incomplete questionnaires were complemented via mail or telephone. Severity of depression was assessed by means of BDI. Out of 211 patients, 199 responded to the questionnaire (94 %). 193 questionnaires were complete (97 %). Forty-two patients affirmed both case-finding questions (22 %). Compared to patients, who did not affirm both questions, these patients had a higher BDI score (19 +/- 8 vs. 7 +/- 5; p two questions were 89 % and 90 %, respectively. The positive and negative predictive value were 60 % and 98 % respectively. The number of confirmed questions (0, 1, 2) correlated well with the BDI score (r (2) = 0.67, p Two standardized questions can identify patients with PSD for further diagnostic evaluation and therapy. Diagnosis of PSD might be facilitated by using them as screening instrument.

America in Perspective: Yesterday's Questions and Today's Students.

Science.gov (United States)

Danzer, Gerald A.

In 1780, a prize was established in France for the best answer to the question; "Was the discovery of America a blessing or a curse to mankind?" This question and its only response from an individual living in America, constitute the basis of a high school history class unit. The background of the question and the content are developed,…

On safety goals and related questions

International Nuclear Information System (INIS)

Kaplan, S.

1985-01-01

The question of what safety goals should be established for nuclear power plants has been receiving a great deal of urgent attention and debate recently, both by those responsible for reactor licensing and by others interested in establishing a quantitative measure of reactor safety. The same question, phrased alternately in the forms: ''What is acceptable risk?'' and ''How safe is safe enough?,'' has been debated extensively for quite a long time. The purpose of the present paper, therefore, is to show that the above questions, taken at face value, exist within an unworkable context, which the authors shall call the Old Regulatory Context (ORC), and that within this context lead to several absurdities. They shall argue that this context needs to be replaced by another context, which they call the Decision Theory Context (DTC), and which the authors discuss here

[Genealogy of the Meckel anatomy family (from Hem[b]sbach)].

Science.gov (United States)

Viebig, Michael; Schultka, Rüdiger

2002-11-01

The main goal of our investigations is to complete the genealogy of the famous Meckel dynasty. It is important to answer a lot of questions which have remained unanswered until now. During the investigations we were able to find the names of three children who died early and were dissected by their father Philipp Friedrich Theodor Meckel (1755-1803). Besides, it was possible to extend distinctly our knowledge of the various genealogical lines of the Meckel family.

Sphagnum moss as a growing media constituent: some effects of harvesting, processing and storage

OpenAIRE

S. Kumar

2017-01-01

The Sphagnum material used in horticulture so far has been harvested manually, and most of the available data about Sphagnum properties have been obtained from this material. A question that remains unanswered is how changes during harvesting and processing, as well as the use of mechanical methods, affect the important properties of Sphagnum moss as a growing media constituent. Some of the effects have been evaluated in Sphagnum farming projects in Germany during the past ten years, and are ...

Lattices with unique complements

CERN Document Server

Saliĭ, V N

1988-01-01

The class of uniquely complemented lattices properly contains all Boolean lattices. However, no explicit example of a non-Boolean lattice of this class has been found. In addition, the question of whether this class contains any complete non-Boolean lattices remains unanswered. This book focuses on these classical problems of lattice theory and the various attempts to solve them. Requiring no specialized knowledge, the book is directed at researchers and students interested in general algebra and mathematical logic.

A Panel data analysis of locational determinants of outward Foreign Direct Investment from China and India

OpenAIRE

Duanmu, J; Guney, Y

2009-01-01

The upsurge of Chinese and Indian outward foreign direct investment (FDI) raises an unanswered question about locational determinants of direct investment from the two countries. Using an unbalanced bilateral FDI database, we find that Chinese and Indian FDI are attracted to countries with large market size, low GDP growth, high volumes of imports from China or India, and low corporate tax rates. We also find important differences between China and India. While Chinese FDI is drawn to countri...

The coal cleat system: A new approach to its study

OpenAIRE

C.F. Rodrigues; C. Laiginhas; M. Fernandes; M.J. Lemos de Sousa; M.A.P. Dinis

2014-01-01

After a general analysis regarding the concept of coal “cleat system”, its genetic origin and practical applications to coalbed methane (CBM) commercial production and to CO2 geological sequestration projects, the authors have developed a method to answer, quickly and accurately in accordance with the industrial practice and needs, the following yet unanswered questions: (1) how to define the spatial orientation of the different classes of cleats presented in a coal seam and (2) how to determ...

Fifty important research questions in microbial ecology.

Science.gov (United States)

Antwis, Rachael E; Griffiths, Sarah M; Harrison, Xavier A; Aranega-Bou, Paz; Arce, Andres; Bettridge, Aimee S; Brailsford, Francesca L; de Menezes, Alexandre; Devaynes, Andrew; Forbes, Kristian M; Fry, Ellen L; Goodhead, Ian; Haskell, Erin; Heys, Chloe; James, Chloe; Johnston, Sarah R; Lewis, Gillian R; Lewis, Zenobia; Macey, Michael C; McCarthy, Alan; McDonald, James E; Mejia-Florez, Nasmille L; O'Brien, David; Orland, Chloé; Pautasso, Marco; Reid, William D K; Robinson, Heather A; Wilson, Kenneth; Sutherland, William J

2017-05-01

Microbial ecology provides insights into the ecological and evolutionary dynamics of microbial communities underpinning every ecosystem on Earth. Microbial communities can now be investigated in unprecedented detail, although there is still a wealth of open questions to be tackled. Here we identify 50 research questions of fundamental importance to the science or application of microbial ecology, with the intention of summarising the field and bringing focus to new research avenues. Questions are categorised into seven themes: host-microbiome interactions; health and infectious diseases; human health and food security; microbial ecology in a changing world; environmental processes; functional diversity; and evolutionary processes. Many questions recognise that microbes provide an extraordinary array of functional diversity that can be harnessed to solve real-world problems. Our limited knowledge of spatial and temporal variation in microbial diversity and function is also reflected, as is the need to integrate micro- and macro-ecological concepts, and knowledge derived from studies with humans and other diverse organisms. Although not exhaustive, the questions presented are intended to stimulate discussion and provide focus for researchers, funders and policy makers, informing the future research agenda in microbial ecology. © FEMS 2017. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

Questions and answers on nuclear energy

International Nuclear Information System (INIS)

1989-04-01

Leading questions about nuclear power are posed. These include questions about how much extra radioactivity in the environments is due to the nuclear industry, the risk of a nuclear accident, radioactive wastes, nuclear power as a solution to the greenhouse effect, alternative energy sources, and the economics of nuclear power. The answers are presented from the view point of the authors, members of Greenpeace. A glossary, notes and references are included. (UK)

Power dynamics and questioning in elementary science lessons

Science.gov (United States)

Reinsvold, Lori Ann

Discourse interactions between a teacher and students in an inquiry-based fourth-grade science classroom were analyzed to investigate how power dynamics and questioning strategies within elementary science lessons help support students in building their science understanding. Five inquiry-based classroom sessions were observed; verbal interactions were audio- and video-recorded. Research data consisted of observation transcripts, teacher interviews, student work, and instructional materials. Analyses were conducted on the frequencies of utterances, participation roles, power categories, and questioning categories. Results revealed that when students used more frequent power, (a) no significant differences were noted between frequencies of teacher and student talk, (b) the teacher posed more questions than did the students, and (c) students explained what they knew and asked questions to clarify their understanding. When the teacher used more frequent power, she asked questions to provide students opportunities to negotiate investigative processes and explain what they knew and how they knew it. Evidence of student understanding of the science concepts was found in how students used subject matter to discuss what they knew and how they knew it. Pre-service and in-service teachers should be encouraged to consider how their use of power and questioning strategies can engage students to reflect on how they build understanding of science concepts. Teachers can use Professional Learning Communities to reflect on how their practice engages students. Future research should be employed to observe classrooms across an entire school year to determine how power and questioning dynamics flow among students and teachers and change over time. Research can also be used to understand the influence of gender and culture on power and questioning dynamics in classroom settings.

The social question revisited

DEFF Research Database (Denmark)

Kenneth, Petersson; Olsson, Ulf; Krejsler, John B.

2015-01-01

The focus of this chapter is the re-installation of the social question as a historical practice. The purpose is to investigate how historic figures return and are applied in contemporary political discourses, more precisely in the context of education, education policy and teacher education...

Michaelis' hundred Questions and the Royal Instructions

DEFF Research Database (Denmark)

Friis, Ib

2017-01-01

Michaelis' 100 questions for the expedition is a remarkable document. It provides insight into the sources and methods of biblical research anno 1762, at the same time as highlighting the challenges the members of the expedition faced. As the scholarly foundation of the expedition, the questions ...

Michaelis' Hundred Questions and the Royal Instruction

DEFF Research Database (Denmark)

Friis, Ib

2015-01-01

Michaelis' 100 questions for the expedition is a remarkable document. It provides insight into the sources and methods of biblical research anno 1762, at the same time as highlighting the challenges the members of the expedition faced. As the scholarly foundation of the expedition, the questions ...

asking questions for higher order thinking in visual literacy

African Journals Online (AJOL)

Numerous factors such as socio-economic back- ground of .... questions should comprise 40% low-order questions (Knowledge), 40% middle-order questions ... The data obtained from the class participants comprise details of a two-step tea-.

Open-ended questions in sensory testing practice

NARCIS (Netherlands)

Piqueras Fiszman, B.

2015-01-01

Why use open-ended questions? This chapter provides an up-to-date overview on the use of open-ended questions in novel rapid sensory methodologies and the potential applications in which they could provide unique benefits. Next, the step-by-step process is described (from task performance to

Questioning Danish Cartoon Images

DEFF Research Database (Denmark)

Bojsen, Heidi

2007-01-01

Danes today when it is considered demeaning and racist in most other countries. The conclusion does emphatically not plead in favour of law enforced limitations of the freedom of expression, but does question the prevalent "freedom of ignorance" concerning black identities which means...

Questions of Authenticity after Six Re-restorations of the Wall Paintings in Fjenneslev Church

DEFF Research Database (Denmark)

Brajer, Isabelle Eve; Haslund, Ida

2005-01-01

This article presents a case involving particularly difficult decisions pertaining to the aesthetic presentation of the Romanesque wall paintings in Fjenneslev Church (Denmark), which have undergone six major re-restorations in the past hundred years. The application of widely acknowledged modern...... ethical principles during the most recent intervention (2003) is questioned, and the result or consequence of an alternative course of action is discussed. The conclusion of these arguments might serve as an illustration for the need to apply a wider set of criteria in special cases where material...