WorldWideScience

Sample records for major results obtained

  1. Experimental results obtained at GANIL

    International Nuclear Information System (INIS)

    Borrel, V.

    1993-01-01

    A review of experimental results obtained at GANIL on the study of nuclear structure and nuclear reactions with secondary radioactive beams is presented. Mass measurements by means of the GANIL cyclotrons are described. The possibilities of GANIL/LISE3 for the production and separation of radioactive beams are illustrated through a large variety of experiments. (author). 19 refs., 8 figs

  2. Overview of galactic results obtained by MAGIC

    Energy Technology Data Exchange (ETDEWEB)

    Zanin, Roberta

    2013-06-15

    MAGIC is a system of two atmospheric Cherenkov telescopes which explores the very-high-energy sky, from some tens of GeV up to tens of TeV. Located in the Canary island of La Palma, MAGIC has the lowest energy threshold among the instruments of its kind, well suited to study the still poorly explored energy band below 100 GeV. Although the space-borne gamma-ray telescope Fermi/LAT is sensitive up to 300 GeV, gamma-ray rates drop fast with increasing energy, so γ-ray collection areas larger than 10{sup 4}m{sup 2}, as those provided by grounds-based instruments, are crucial above a few GeV. The combination of MAGIC and Fermi/LAT observations have provided the first astrophysical spectra sampled in the inverse Compton peak region, resulting in a complete coverage from MeV up to TeV energies, as well as the discovery of a pulsed emission in the very-high-energy band. This paper focuses on the latest results on Galactic sources obtained by MAGIC which are highlighted by the detection of the pulsed gamma-ray emission from the Crab pulsar up to 400 GeV. In addition, we will present the morphological study on the W51 complex which allowed to pinpoint the location of the majority of the emission around the interaction point between the supernova remnant W51C and the star forming region W51B, but also to find a possible contribution from the associated pulsar wind nebula. Other important scientific achievements involve the Crab Nebula with an unprecedented spectrum covering three decades in energy starting from 50 GeV and a morphological study of the unidentified source HESS J1857+026 which supports the pulsar wind nebula scenario. Finally we will report on the searches of very-high-energy signals from gamma-ray binaries, mainly LS I 303+ and HESS J0632+057.

  3. Major components in oils obtained from Amazonian palm fruits

    Directory of Open Access Journals (Sweden)

    Santos, M. F. G.

    2013-06-01

    Full Text Available Native palm trees belong to the Arecaceae family and are among the most useful plant resources in the Amazons. Despite its great diversity and various uses, few species have been study in detail, which makes it necessary to perform more comprehensive studies on the quality and composition of species not yet explored. This study deals with the characterization of the major compounds in the oils obtained from the mesocarp of fruits of the main palm species from the State of Amapá, Brasil, i.e. bacaba (Oenocarpus bacaba, buriti (Mauritia flexuosa, inajá (Maximiliana maripa, pupunha (Bactris gasipaes and tucumã (Astrocaryum vulgare. Physicochemical characteristics, fatty acids and triacylglycerol (TAG contents were analyzed by HPLC and GC. The proximate composition of the fruits was also analyzed. The results relating to acidity, peroxide value and polar compounds indicate good quality of the oils obtained. Oleic acid ranging from 39.2 to 71.6% and palmitic acid ranging from 20.8 to 39.6% were the two major fatty acids in all the samples. The oils from inajá were characterized by the presence of significant amounts of lauric (4.6% and miristic (10.7% acids while in bacaba, buriti, pupunha and tucumã, as in most edible vegetable oils, only the fatty acids of 16 and 18 carbon atoms were present. Accordingly, the major TAG species in all the samples were POP, POO and OOO. The mesocarp of the palm fruit had a high content in lipids ranging from 17.0% for pupunha to 38.3% for bacaba, expressed as dry basis.Las palmeras nativas de la familia Arecaceae constituyen recursos alimentarios de gran importancia en la región amazónica. A pesar de su diversidad y utilidad, muchas especies son poco conocidas por lo que son de interés los estudios dirigidos a conocer la calidad y composición de las especies menos exploradas para evaluar su potencial económico. El objetivo de este estudio fue la caracterización de los aceites obtenidos del mesocarpio

  4. Results obtained on dileptons and prospects

    International Nuclear Information System (INIS)

    Roche, G.

    1992-01-01

    Experimental results (mostly from the DLS collaboration at LBL) and model calculations of dielectron production in pp/pd/pBe (1-5 GeV) and CaCa (1-2 GeV/A) are presented. Dileptons appear to be a suitable probe to approach in-medium properties of hadrons in nuclear matter. At the present time, the ρ/ω region looks the most promising. Oncoming programs are briefly presented, in particular the HADES project at GSI. 7 figs

  5. Test Beam Results Obtained with the Q4 Prototype

    Energy Technology Data Exchange (ETDEWEB)

    Aguilar-Benitez, M.; Alberdi, J.; Cerrada, M.; Colino, N.; Daniel, M.; Fouz, M. c.; Marin, J.; Mocholi, J.; Oller, J. C.; Puerta, J.; Romero, L.; Salicio, J. M.

    2000-07-01

    A prototype of the CMS Barrel Muon Detector incorporating all the features of the final chambers was built at CIEMAT using the mass production assembly procedures and tools. The performance of this prototype was studied in a muon test beam at CERN and the results obtained are presented here. (Author)

  6. Test beam results obtained with the Q4 prototype

    International Nuclear Information System (INIS)

    Aguilar-Benitez, M.; Alberdi, J.; Cerrada, M.; Colino, N.; Daniel, M.; Fouz, M.C.; Marin, J.; Mocholi, J.; Oller, J. C.; Puerta, J.; Romero, L.; Salicio, J. M.; Willmott, C.

    2000-10-01

    A prototype of the CMS Barrel Muon Detector incorporating all the features of the final chambers was built at CIEMAT using the mass production assembly procedures and tools. The performance of this prototype was studied in a muon test beam at CERN and the results obtained are presented here. (Author)

  7. DIFFERENCES IN RESULTS OBTAINED BY STUDENTS OF DIFFERENT FACULTIES

    Directory of Open Access Journals (Sweden)

    OTAVOVÁ, Miroslava

    2016-03-01

    Full Text Available The paper presents and discusses the results of statistical analysis of differences among scores obtained by students of different faculties of the University of Economics in Prague. The analysed dataset contains the scores for 2256 students that took basic mathematics course during the academic year 2013/2014. A two way analysis of variance was performed with semester and faculty as main factors. The interaction between these two factors was also considered. Students have to take two tests. At first, the sum of the scores obtained from both tests is analysed and then, the two tests are analysed separately. It turns out that the significance of factors is the same in the three analyses. The assumptions of linear models are verified. Due to problem of heteroscedasticity, weighted least squares are used and the possibility of using Box-Cox transformation is also discussed, as the errors are not normally distributed. Finally, the differences between the faculties are described.

  8. Lambing results obtained with imported Ile de France rarn semen

    African Journals Online (AJOL)

    insemination was carried out either 54,5 h (fixed time single ... Table 1 Conception rate obtained using two batches of frozen lle de France ... Pregnant mare serum gonadotrophin (Fostim, 300 ... Effect of initial freezing temperature, addition.

  9. Novel Design for Quantum Dots Cellular Automata to Obtain Fault-Tolerant Majority Gate

    International Nuclear Information System (INIS)

    Razieh Farazkish, R.; Sayedsalehi, S.; Navi, K.

    2012-01-01

    Quantum-dot Cellular Automata (QCA) is one of the most attractive technologies for computing at nano scale. The principle element in QCA is majority gate. In this paper, fault-tolerance properties of the majority gate is analyzed. This component is suitable for designing fault-tolerant QCA circuits. We analyze fault-tolerance properties of three-input majority gate in terms of misalignment, missing, and dislocation cells. In order to verify the functionality of the proposed component some physical proofs using kink energy (the difference in electrostatic energy between the two polarization states) and computer simulations using QCA Designer tool are provided. Our results clearly demonstrate that the redundant version of the majority gate is more robust than the standard style for this gate.

  10. Novel Design for Quantum Dots Cellular Automata to Obtain Fault-Tolerant Majority Gate

    Directory of Open Access Journals (Sweden)

    Razieh Farazkish

    2012-01-01

    Full Text Available Quantum-dot Cellular Automata (QCA is one of the most attractive technologies for computing at nanoscale. The principle element in QCA is majority gate. In this paper, fault-tolerance properties of the majority gate is analyzed. This component is suitable for designing fault-tolerant QCA circuits. We analyze fault-tolerance properties of three-input majority gate in terms of misalignment, missing, and dislocation cells. In order to verify the functionality of the proposed component some physical proofs using kink energy (the difference in electrostatic energy between the two polarization states and computer simulations using QCA Designer tool are provided. Our results clearly demonstrate that the redundant version of the majority gate is more robust than the standard style for this gate.

  11. Preliminary results obtained from a dense plasma focus

    International Nuclear Information System (INIS)

    Sinman, S.; Sinman, A.

    1982-01-01

    In this study, for the data processing in our Dense Plasma Focus (DPF) system, a multiparameters numerical hierarchy obtained from the fundamental equations based on the snowplows model and its conclusions have been developed. Evaluating the data along the transients of the total plasma current, the anode current and the focus voltage recorded by an oscilloscope, they have been possible to determine the time domain plasma parameters such as the shock thickness, the sheath temperature, velocity and electron density, the pressure at the focus phase and the plasma temperature. Besides, the dissipated energy through the focus notch or in other words, the plasma temperature has also been calculated by means of the numerical integration. In the text, a performance chart together with some other correlation curves for the optimization of the DPF systems are submitted and discussed. (author)

  12. Results Obtained in Training Romanian Sport Horses for Jumping Competitions

    Directory of Open Access Journals (Sweden)

    Flavia Luminiţa Bochiş

    2012-10-01

    Full Text Available A number of 29 equines, Romanian Sport Horse stallions, were taken as green horses, break into the saddle, andteach into basic training while later train as jumpers over three years. The obstacle courses results had been obtainedin our country, in Hungary and in Serbia. There were courses jumped in the national championship, somedemonstrations organized in Romania or in the two foreign countries, or periodically test pattern courses run on theown arena. The best results, respectively more than 50% obstacle courses with no fault points over 3 years, were runby five stallions, and the same percent for 2 seasons, was reached by nine stallions.

  13. Paternity tests in Mexico: Results obtained in 3005 cases.

    Science.gov (United States)

    García-Aceves, M E; Romero Rentería, O; Díaz-Navarro, X X; Rangel-Villalobos, H

    2018-04-01

    National and international reports regarding the paternity testing activity scarcely include information from Mexico and other Latin American countries. Therefore, we report different results from the analysis of 3005 paternity cases analyzed during a period of five years in a Mexican paternity testing laboratory. Motherless tests were the most frequent (77.27%), followed by trio cases (20.70%); the remaining 2.04% included different cases of kinship reconstruction. The paternity exclusion rate was 29.58%, higher but into the range reported by the American Association of Blood Banks (average 24.12%). We detected 65 mutations, most of them involving one-step (93.8% and the remaining were two-step mutations (6.2%) thus, we were able to estimate the paternal mutation rate for 17 different STR loci: 0.0018 (95% CI 0.0005-0.0047). Five triallelic patterns and 12 suspected null alleles were detected during this period; however, re-amplification of these samples with a different Human Identification (HID) kit confirmed the homozygous genotypes, which suggests that most of these exclusions actually are one-step mutations. HID kits with ≥20 STRs detected more exclusions, diminishing the rate of inconclusive results with isolated exclusions (Powerplex 21 kit (20 STRs) and Powerplex Fusion kit (22 STRs) offered similar PI (p = 0.379) and average number of exclusions (PE) (p = 0.339) when a daughter was involved in motherless tests. In brief, besides to report forensic parameters from paternity tests in Mexico, results describe improvements to solve motherless paternity tests using HID kits with ≥20 STRs instead of one including 15 STRs. Copyright © 2018 Elsevier Ltd and Faculty of Forensic and Legal Medicine. All rights reserved.

  14. Results obtained by Trillo Nuclear Power Plant in 2001

    International Nuclear Information System (INIS)

    Solar, V.

    2002-01-01

    Unification of the Almaraz and Trillo plant managements was given a strong boost with unification of the central offices and management computer platforms (economic and technical) and with signature of an agreement with Madrid's trade unions providing for appropriate management of surpluses and the transfer of knowledge between people leaving the company and those taking their place. The operating results have been maintained at a high level although they were lower than last year, which was exceptional. The plant was on line for 7,979 hours, most of them at full load. (Author)

  15. Measurement results obtained from air quality monitoring system

    Energy Technology Data Exchange (ETDEWEB)

    Turzanski, P.K.; Beres, R. [Provincial Inspection of Environmental Protection, Cracow (Poland)

    1995-12-31

    An automatic system of air pollution monitoring operates in Cracow since 1991. The organization, assembling and start-up of the network is a result of joint efforts of the US Environmental Protection Agency and the Cracow environmental protection service. At present the automatic monitoring network is operated by the Provincial Inspection of Environmental Protection. There are in total seven stationary stations situated in Cracow to measure air pollution. These stations are supported continuously by one semi-mobile (transportable) station. It allows to modify periodically the area under investigation and therefore the 3-dimensional picture of creation and distribution of air pollutants within Cracow area could be more intelligible.

  16. The similia principle: results obtained in a cellular model system.

    Science.gov (United States)

    Wiegant, Fred; Van Wijk, Roeland

    2010-01-01

    This paper describes the results of a research program focused on the beneficial effect of low dose stress conditions that were applied according to the similia principle to cells previously disturbed by more severe stress conditions. In first instance, we discuss criteria for research on the similia principle at the cellular level. Then, the homologous ('isopathic') approach is reviewed, in which the initial (high dose) stress used to disturb cellular physiology and the subsequent (low dose) stress are identical. Beneficial effects of low dose stress are described in terms of increased cellular survival capacity and at the molecular level as an increase in the synthesis of heat shock proteins (hsps). Both phenomena reflect a stimulation of the endogenous cellular self-recovery capacity. Low dose stress conditions applied in a homologous approach stimulate the synthesis of hsps and enhance survival in comparison with stressed cells that were incubated in the absence of low dose stress conditions. Thirdly, the specificity of the low dose stress condition is described where the initial (high dose) stress is different in nature from the subsequently applied (low dose) stress; the heterologous or 'heteropathic' approach. The results support the similia principle at the cellular level and add to understanding of how low dose stress conditions influence the regulatory processes underlying self-recovery. In addition, the phenomenon of 'symptom aggravation' which is also observed at the cellular level, is discussed in the context of self-recovery. Finally, the difference in efficiency between the homologous and the heterologous approach is discussed; a perspective is indicated for further research; and the relationship between studies on the similia principle and the recently introduced concept of 'postconditioning hormesis' is emphasized. Copyright 2009 The Faculty of Homeopathy. Published by Elsevier Ltd. All rights reserved.

  17. Results obtained using the pellet charge exchange diagnostic on TFTR

    International Nuclear Information System (INIS)

    McChesney, J.M.; Fisher, R.K.; Parks, P.B.; Duong, H.H.; Mansfield, D.K.; Medley, S.S.; Roquemore, A.L.; Petrov, M.P.

    1994-05-01

    Experiments are underway on TFTR to measure the confined alpha particle distribution functions using small low-Z pellets injected into the plasma. Upon entering the plasma, the pellet ablates, forming a plasma ablation cloud, elongated in the magnetic field direction, that travels alongside the pellet. A small fraction of the fusion produced 3.5 MeV alpha particles incident on the cloud are converted to helium neutrals. By measuring the resultant helium neutrals escaping from the plasma by means of a mass and energy resolving charge exchange analyzer, the energy distribution of the alpha particles incident on the cloud can be inferred. Preliminary experiments to observe neutrals from the 100-1000 keV He tail produced during ICRF minority heating experiments were successful. However, no significant alpha particle signals have been observed during D-T operation on TFTR. The authors attribute this lack of signal to stochastic toroidal field ripple loss in the outer regions of the plasma. They are studying ways to improve the pellet penetration so that the pellet penetrates into the central regions of the plasma where ripple induced losses are small and the alpha population is high

  18. Does major depression result in lasting personality change?

    Science.gov (United States)

    Shea, M T; Leon, A C; Mueller, T I; Solomon, D A; Warshaw, M G; Keller, M B

    1996-11-01

    Individuals with a history of depression are characterized by high levels of certain personality traits, particularly neuroticism, introversion, and interpersonal dependency. The authors examined the "scar hypothesis," i.e., the possibility that episodes of major depression result in lasting personality changes that persist beyond recovery from the depression. A large sample of first-degree relatives, spouses, and comparison subjects ascertained in connection with the proband sample from the National Institute of Mental Health Collaborative Program on the Psychobiology of Depression were assessed at two points in time separated by an interval of 6 years. Subjects with a prospectively observed first episode of major depression during the interval were compared with subjects remaining well in terms of change from time 1 to time 2 in self-reported personality traits. All subjects studied were well (had no mental disorders) at the time of both assessments. There was no evidence of negative change from premorbid to postmorbid assessment in any of the personality traits for subjects with a prospectively observed first episode of major depression during the interval. The results suggested a possible association of number and length of episodes with increased levels of emotional reliance and introversion, respectively. The findings suggest that self-reported personality traits do not change after a typical episode of major depression. Future studies are needed to determine whether such change occurs following more severe, chronic, or recurrent episodes of depression.

  19. Phytotoxicity of the organic phase and major compound obtained from the fruit pulp of Crescentia cujete L. (Bignoniaceae

    Directory of Open Access Journals (Sweden)

    Sinval Garcia Pereira

    2015-09-01

    Full Text Available http://dx.doi.org/10.5007/2175-7925.2015v28n4p51 The phytotoxity of ethanol extracts, of the organic phase and major compound (cinnamic acid obtained from the fruit pulp of Crescentia cujete L., were evaluated for their potential to inhibit seed germination, hypocotyl development and radicle development of the invasive weeds Senna obtusifolia (L. Irwin & Barneby and Mimosa pudica Mill. The organic phase at a concentration of 0.5% inhibited 100% seed germination of both weeds. Cinnamic acid obtained from the organic phase inhibited seed germination by 95% for S. obtusifolia and 99% for M. pudica at a concentration of 0.1%, with concentrations (% inhibiting 50% (IC50 seed germination equal to 0.063% and 0.037%, respectively. For the seedling growth bioassays, the toxicity of the cinnamic acid was more efficient for the S. obtusifolia radicle (IC50 equal to 0.009%, and for M. pudica the IC50 values were 0.097% and 0.117% for the radicle and hypocotyl, respectively. This research reinforces the phytotoxic potential of cinnamic acid, verified initially in the organic phase (in ethyl acetate, which is rich in this phenylpropanoid. he rainiest months in the Amazon region. The increased BAP and GA3 concentrations in the culture medium provided significant improvements in the material multiplication rates. In spite of the results obtained, the species shows peculiarities and limitations to in vitro cultivation that were identified and described in this paper.

  20. Deep-sequencing protocols influence the results obtained in small-RNA sequencing.

    Directory of Open Access Journals (Sweden)

    Joern Toedling

    Full Text Available Second-generation sequencing is a powerful method for identifying and quantifying small-RNA components of cells. However, little attention has been paid to the effects of the choice of sequencing platform and library preparation protocol on the results obtained. We present a thorough comparison of small-RNA sequencing libraries generated from the same embryonic stem cell lines, using different sequencing platforms, which represent the three major second-generation sequencing technologies, and protocols. We have analysed and compared the expression of microRNAs, as well as populations of small RNAs derived from repetitive elements. Despite the fact that different libraries display a good correlation between sequencing platforms, qualitative and quantitative variations in the results were found, depending on the protocol used. Thus, when comparing libraries from different biological samples, it is strongly recommended to use the same sequencing platform and protocol in order to ensure the biological relevance of the comparisons.

  1. Marketing paediatric influenza vaccination: results of a major metropolitan trial

    Science.gov (United States)

    Van Buynder, Paul G.; Carcione, Dale; Rettura, Vince; Daly, Alison; Woods, Emily

    2010-01-01

    Please cite this paper as: Van Buynder et al. (2010) Marketing paediatric influenza vaccination: results of a major metropolitan trial. Influenza and Other Respiratory Viruses 5(1), 33–38. Objectives  After a cluster of rapidly fulminant influenza related toddler deaths in a Western Australian metropolis, children aged six to 59 months were offered influenza vaccination in subsequent winters. Some parental resistance was expected and previous poor uptake of paediatric influenza vaccination overseas was noted. A marketing campaign addressing barriers to immunization was developed to maximise uptake. Design  Advertising occurred in major statewide newspapers, via public poster displays and static ‘eye‐lite’ displays, via press releases, via a series of rolling radio advertisements, via direct marketing to child care centres, and via a linked series of web‐sites. Parents were subsequently surveyed to assess reasons for vaccination. Main Outcome Results  The campaign produced influenza vaccination coverage above that previously described elsewhere and led to a proportionate reduction in influenza notifications in this age group compared to previous seasons. Conclusions  Influenza in children comes with significant morbidity and some mortality. Paediatric influenza vaccination is safe, well tolerated and effective if two doses are given. A targeted media campaign can increase vaccine uptake if it reinforces the seriousness of influenza and addresses community ‘myths’ about influenza and influenza vaccine. The lessons learned enabling enhancements of similar programs elsewhere. PMID:21138538

  2. DOES M31 RESULT FROM AN ANCIENT MAJOR MERGER?

    International Nuclear Information System (INIS)

    Hammer, F.; Wang, J. L.; Puech, M.; Flores, H.; Fouquet, S.; Yang, Y. B.

    2010-01-01

    The M31 haunted halo is likely associated with a rich merger history, currently assumed to be caused by multiple minor mergers. Here we use the GADGET2 simulation code to test whether M31 could have experienced a major merger in its past history. Our results indicate that a (3 ± 0.5):1 gaseous-rich merger with r pericenter = 25 ± 5 kpc and a polar orbit can explain many properties of M31 and of its halo. The interaction and fusion may have begun 8.75 ± 0.35 and 5.5 ± 0.5 Gyr ago, respectively. Observed fractions of the bulge and the thin and thick disks can be retrieved for a star formation history that is almost quiescent before the fusion. This also accords well with the observed relative fractions of intermediate age and old stars in both the thick disk and the Giant Stream. In this model, the Giant Stream is caused by returning stars from a tidal tail which contains material previously stripped from the satellite prior to the fusion. These returning stars are trapped into elliptical orbits or loops for long periods of time which can reach a Hubble time, and belong to a plane that is 45 0 offset from the M31 disk position angle. Because these streams of stars are permanently fed by new infalling stars with high energy from the tidal tail, we predict large loops which scale rather well with the features recently discovered in the M31 outskirts. We demonstrate that a single merger could explain first-order (intensity and size), morphological, and kinematical properties of the disk, thick disk, bulge, and streams in the halo of M31, as well as the observed distribution of stellar ages, and perhaps metallicities. This challenges the current scenarios assuming that each feature in the disk (the 10 kpc ring) or in its outskirts (thick disk, the Giant Stream, and the numerous streams) is associated with an equivalent number of minor mergers. Given the large number of parameters, further constraints are certainly required to better render the complexity of M31 and

  3. The interrelation between premenstrual syndrome and major depression: Results from a population-based sample

    Directory of Open Access Journals (Sweden)

    Weiss Carine

    2011-10-01

    Full Text Available Abstract Background Research about the relationship between premenstrual syndrome (PMS and major depression is limited. This study examined the relationship between moderate to severe PMS and major depression in a population-based sample of women of reproductive age. The objectives of the study were to assess the association between premenstrual syndrome and major depression, to analyse how PMS and major depression differ and to characterise the group of women who report both PMS and major depression. Methods Data were obtained from the Swiss Health Survey 2007. Included in the analysis was data from women under the age of 55 without hysterectomy and who answered the questions on PMS symptoms. The population-based sample consisted of 3518 women. Weighted prevalence rates were calculated and relative risk ratios for PMS, major depression and women who reported both PMS and major depression, were calculated with logistic multinominal logit regression. Results The prevalence of major depression was 11.3% in women screening positive for moderate PMS and 24.6% in women screening positive for severe PMS. Compared to women without any of these conditions, women who reported moderate to severe alcohol consumption had a lower risk for PMS. Women reporting use of antidepressants, and use of oral contraceptives had a higher risk for major depression compared to women without any of these conditions. Women reporting work dissatisfaction had a higher risk for PMS. A higher relative risk to report both PMS and major depression compared to women without PMS or major depression was related to factors such as high psychological distress, low mastery, psychotropic drug consumption, and low self-rated health. Conclusions The results suggested that women who suffer from both PMS and major depression are more impaired compared to women with only one disorder. The results further indicated that PMS and major depression are different disorders that can, however, co-occur.

  4. Self-propelled prospection methodology: first results obtained in the northeast basin (Uruguay)

    International Nuclear Information System (INIS)

    Goso, H; Spoturno, J; Peciozzi, F.

    2008-01-01

    This report refers about uranium prospection methodology in Uruguay and its first results obtained in the northeast basin.The preliminary radiometric researching is carried out four works phases: material preparation, radiometric, statistics analysis, anomalies revision

  5. CIEMAT interlaboratories comparison of the results obtained in the proficiency test run by IAEA

    International Nuclear Information System (INIS)

    Gasco, C.; Anton, M. P.; Alvarez, A.; Navarro, N.; Meral, J.; Gonzalez, A.; Higueras Lafaja, E.

    2000-01-01

    This report contains the results obtained by two different laboratories from CIEMAT after participating in the Proficiency Test organised by IAEA (International Atomic Energy Agency) in 1999. This test involves the analysis of fly ashes containing natural radionuclides and different amounts of added transuranics. The extraction techniques, counting methods and results obtained are detailed. This type of test are used for the labs to achieve their accreditation and check the reliability of the procedures routinely employed. (Author) 4 refs

  6. Analysis of the results obtained by optical measurements in plasma focus equipments

    International Nuclear Information System (INIS)

    Bilbao, L.; Bruzzone, H.

    1982-01-01

    The results obtained by shadow and Schlieren photographies and interferometry in a 1MJ plasma focus device of Frascati (CNEN-EURATOM, Italy) are compared with a great number of similar measurement results in several devices of the world. A critical analysis of the above results is presented. (L.C.) [pt

  7. Marketing paediatric influenza vaccination: results of a major metropolitan trial.

    Science.gov (United States)

    Van Buynder, Paul G; Carcione, Dale; Rettura, Vince; Daly, Alison; Woods, Emily

    2011-01-01

    After a cluster of rapidly fulminant influenza related toddler deaths in a Western Australian metropolis, children aged six to 59 months were offered influenza vaccination in subsequent winters. Some parental resistance was expected and previous poor uptake of paediatric influenza vaccination overseas was noted. A marketing campaign addressing barriers to immunization was developed to maximise uptake. Advertising occurred in major statewide newspapers, via public poster displays and static 'eye-lite' displays, via press releases, via a series of rolling radio advertisements, via direct marketing to child care centres, and via a linked series of web-sites. Parents were subsequently surveyed to assess reasons for vaccination. The campaign produced influenza vaccination coverage above that previously described elsewhere and led to a proportionate reduction in influenza notifications in this age group compared to previous seasons. Influenza in children comes with significant morbidity and some mortality. Paediatric influenza vaccination is safe, well tolerated and effective if two doses are given. A targeted media campaign can increase vaccine uptake if it reinforces the seriousness of influenza and addresses community 'myths' about influenza and influenza vaccine. The lessons learned enabling enhancements of similar programs elsewhere. © 2010 Blackwell Publishing Ltd.

  8. Comparison of the results of radiation transport calculation obtained by means of different programs

    International Nuclear Information System (INIS)

    Gorbatkov, D.V.; Kruchkov, V.P.

    1995-01-01

    Verification of calculational results of radiation transport, obtained by the known, programs and constant libraries (MCNP+ENDF/B, ANISN+HILO, FLUKA92) by means of their comparison with the precision results calculations through ROZ-6N+Sadko program constant complex and with experimental data, is carried out. Satisfactory agreement is shown with the MCNP+ENDF/B package data for the energy range of E<14 MeV. Analysis of the results derivations, obtained trough the ANISN-HILO package for E<400 MeV and the FLUKA92 programs of E<200 GeV is carried out. 25 refs., 12 figs., 3 tabs

  9. Phytotoxicity of the organic phase and major compound obtained from the fruit pulp of Crescentia cujete L. (Bignoniaceae

    Directory of Open Access Journals (Sweden)

    Sinval Garcia Pereira

    2015-12-01

    Full Text Available The phytotoxity of ethanol extracts, of the organic phase and major compound (cinnamic acid obtained from the fruit pulp of Crescentia cujete L., were evaluated for their potential to inhibit seed germination, hypocotyl development and radicle development of the invasive weeds Senna obtusifolia (L. Irwin & Barneby and Mimosa pudica Mill. The organic phase at a concentration of 0.5% inhibited 100% seed germination of both weeds. Cinnamic acid obtained from the organic phase inhibited seed germination by 95% for S. obtusifolia and 99% for M. pudica at a concentration of 0.1%, with concentrations (% inhibiting 50% (IC50 seed germination equal to 0.063% and 0.037%, respectively. For the seedling growth bioassays, the toxicity of the cinnamic acid was more efficient for the S. obtusifolia radicle (IC50 equal to 0.009%, and for M. pudica the IC50 values were 0.097% and 0.117% for the radicle and hypocotyl, respectively. This research reinforces the phytotoxic potential of cinnamic acid, verified initially in the organic phase (in ethyl acetate, which is rich in this phenylpropanoid.

  10. The major results of the PISC II RRT

    International Nuclear Information System (INIS)

    Crutzen, S.; Jehenson, P.; McDonald, N.

    1989-01-01

    Non Destructive Testing (NDT) forms part of the in-service inspection (ISI) of a reactor pressure vessel (RPV) and its associated pressure circuit, and the results of the NDT are used in conjunction with fracture mechanics or as part of a code-defined treatment to assess the significance of flaws. Detection, location and sizing of crack-like flaws play an important role in helping to establish the integrity of these reactor steel structures. (orig.)

  11. Misleading reporting and interpretation of results in major infertility journals.

    Science.gov (United States)

    Glujovsky, Demian; Sueldo, Carlos E; Borghi, Carolina; Nicotra, Pamela; Andreucci, Sara; Ciapponi, Agustín

    2016-05-01

    To evaluate the proportion of randomized controlled trials (RCTs) published in top infertility journals indexed on PubMed that reported their results with proper effect estimates and their precision estimation, while correctly interpreting both measures. Cross-sectional study evaluating all the RCTs published in top infertility journals during 2014. Not applicable. Not applicable. Not applicable. Proportion of RCTs that reported both relative and absolute effect size measures and its precision. Among the 32 RCTs published in 2014 in the top infertility journals reviewed, 37.5% (95% confidence interval [CI], 21.1-56.3) did not mention in their abstracts whether the difference among the study arms was statistically or clinically significant, and only 6.3% (95% CI, 0.8-20.8) used a CI of the absolute difference. Similarly, in the results section, these elements were observed in 28.2% (95% CI, 13.7-46.7) and 15.6% (95% CI, 5.3-32.8), respectively. Only one study clearly expressed the minimal clinically important difference in their methods section, but we found related proxies in 53% (95% CI, 34.7-70.9). None of the studies used CIs to draw conclusions about the clinical or statistical significance. We found 13 studies where the interpretation of the findings could be misleading. Recommended reporting items are underused in top infertility journals, which could lead to misleading interpretations. Authors, reviewers, and editorial boards should emphasize their use to improve reporting quality. Copyright © 2016 American Society for Reproductive Medicine. Published by Elsevier Inc. All rights reserved.

  12. The major results from W7-AS stellarator

    Science.gov (United States)

    Wagner, Friedrich

    2002-11-01

    W7-AS has terminated operation this summer. In the last phase, W7-AS was equipped with an island divertor using the natural edge islands of the low-shear, n=5 design. NBI heating has been done with co-injection (3 MW), ECRH was successfully extended to high density with the OXB scheme, and ICRH was applied in all standard modes but also in beach wave heating. The island divertor allowed high β and provided excellent exhaust conditions thanks to the accessibility to high densities (ne rationals; in the plasma core the neo-classical bifurcation between ion and electron roots is observed. A distinct difference to tokamaks is the lack of Te - profile resilience. The H-mode operational range is governed by poloidal flow damping. At high density, a further bifurcation appears into a regime characterised by good energy and low impurity confinement (HDH). Because of its appealing features, this regime will be described in detail. The most visible MHD are beam driven global Alfven modes and ELMs. The operational limits are set by NBI power: The balance of heating and edge radiation determines the density limit; the maximal β is limited to 3.1%. The operation at high densities and high β is quiescent and quasi-steady state. The intrinsic stellarator features - steady state and no disruptions - remain close to operational limits. The results of W7-AS confirm the design criteria of W7-X and contribute to establish the stellarator line as independent route to a reactor.

  13. Brief review of topmost scientific results obtained in 2016 at the Joint Institute for Nuclear Research

    International Nuclear Information System (INIS)

    Kravchenko, E.I.; Sabaeva, E.V.

    2017-01-01

    This brief review presents the topmost scientific results obtained in 2016 at the Joint Institute for Nuclear Research in such fields as theoretical and experimental physics, radiation and radiobiological research, accelerators, information technology and computer physics. It also provides information about the publications by JINR staff members and activities carried out at the JINR University Centre in 2016. [ru

  14. Brief review of topmost scientific results obtained in 2015 at the Joint Institute for Nuclear Research

    International Nuclear Information System (INIS)

    Sabaeva, E.V.; Krupko, E.I.

    2016-01-01

    This brief review presents the topmost scientific results obtained in 2015 at the Joint Institute for Nuclear Research in such fields as theoretical and experimental physics, radiation and radiobiological research, accelerators, information technology and computer physics. It also provides information about the publications by JINR staff members, awards given to JINR scientists, and activities carried out at the JINR University Centre in 2015. [ru

  15. An overview of results obtained in intercomparison exercises for determination of actinides

    International Nuclear Information System (INIS)

    Benedik, L.

    2013-01-01

    In recent years the Jožef Stefan Institute participated in numerous intercomparison exercises for determination of natural and man-made radionuclides. The reported values were mostly in good agreement with the resulting reference values. This paper describes an analysis of the measurement results obtained in intercomparison exercises for determination of actinides in the period from 2009 to 2011, organised by the National Physical Laboratory and the Bundesamt für Strahlenschutz. The review covers neptunium, plutonium and americium radioisotopes over this period. - Highlights: • The goal of this study is an overview of results obtained in intercomparison exercises for determination of actinides. • The disagreement of results for Np-237 was evaluated. • Improvements in separation procedures were done

  16. Near-Infrared Scintillation of Liquid Argon: Recent Results Obtained with the NIR Facility at Fermilab

    Energy Technology Data Exchange (ETDEWEB)

    Escobar, C. O. [Fermilab; Rubinov, P. [Fermilab; Tilly, E. [Sewanee U.

    2018-03-19

    After a short review of previous attempts to observe and measure the near-infrared scintillation in liquid argon, we present new results obtained with NIR, a dedicated cryostat at the Fermilab Proton Assembly Building (PAB). The new results give confidence that the near-infrared light can be used as the much needed light signal in large liquid argon time projection chambers.11 pages,

  17. Acoustic emission results obtained from testing the ZB-1 intermediate scale pressure vessel

    International Nuclear Information System (INIS)

    Hutton, P.H.; Kurtz, R.J.; Pappas, R.A.; Dawson, J.F.; Dake, L.S.; Skorpik, J.R.

    1985-09-01

    Acoustic emission (AE) monitoring of flaw growth in an intermediate scale vessel during cyclic loading at 65 0 C and 288 0 C is described in this report. The report deals with background, methodology, and results. The work discussed is of major significance in a program supported by NRC to develop and demonstrate application of AE monitoring for continuous surveillance of reactor pressure boundaries to detect and evaluate growing flaws. Several areas of technical concern are addressed. Results support the feasibility of effective continuous monitoring

  18. LEP and results obtained by DELPHI after four years of operation

    International Nuclear Information System (INIS)

    Blocki, J.

    1993-10-01

    We characterize the most important problems of modern elementary particles physics, for the solution of which the LEP (Large Electron Positron) accelerator was built. We present the characteristics of this accelerator. The structure and properties of the DELPHI detector are described with special emphasis on the contribution of Polish groups. The most important results obtained so far in the LEP accelerator are discussed. (author). 12 refs, 17 figs, 1 tab

  19. Brief review of topmost scientific results obtained in 2013 at the Joint Institute for Nuclear Research

    International Nuclear Information System (INIS)

    Sabaeva, E.V.; Kravchenko, E.I.

    2014-01-01

    This brief review presents the topmost scientific results obtained in 2013 at the Joint Institute for Nuclear Research in such areas as theoretical physics, experimental physics, radiation and radiobiological research, accelerators, information technology and computer physics. It also provides information on the number of publications by JINR staff members, awards given to JINR scientists, and activities carried out at the JINR University Centre in 2013.

  20. Brief review of topmost scientific results obtained in 2014 at the Joint Institute for Nuclear Research

    International Nuclear Information System (INIS)

    Bulatova, V.V.; Sabaeva, E.V.

    2015-01-01

    This brief review presents the topmost scientific results obtained in 2014 at the Joint Institute for Nuclear Research in such fields as theoretical and experimental physics, radiation and radiobiological research, accelerators, information technology and computer physics. It also provides information about the publications by JINR staff members, patents for inventions, awards given to JINR scientists, and activities carried out at the JINR University Centre in 2014. [ru

  1. Obtaining patient test results from clinical laboratories: a survey of state law for pharmacists.

    Science.gov (United States)

    Witry, Matthew J; Doucette, William R

    2009-01-01

    To identify states with laws that restrict to whom clinical laboratories may release copies of laboratory test results and to describe how these laws may affect pharmacists' ability to obtain patient laboratory test results. Researchers examined state statutes and administrative codes for all 50 states and the District of Columbia at the University of Iowa Law Library between June and July 2007. Researchers also consulted with lawyers, state Clinical Laboratory Improvement Amendments officers, and law librarians. Laws relating to the study objective were analyzed. 34 jurisdictions do not restrict the release of laboratory test results, while 17 states have laws that restrict to whom clinical laboratories can send copies of test results. In these states, pharmacists will have to use alternative sources, such as physician offices, to obtain test results. Pharmacists must consider state law before requesting copies of laboratory test results from clinical laboratories. This may be an issue that state pharmacy associations can address to increase pharmacist access to important patient information.

  2. Results of Investigative Tests of Gas Turbine Engine Compressor Blades Obtained by Electrochemical Machining

    Science.gov (United States)

    Kozhina, T. D.; Kurochkin, A. V.

    2016-04-01

    The paper highlights results of the investigative tests of GTE compressor Ti-alloy blades obtained by the method of electrochemical machining with oscillating tool-electrodes, carried out in order to define the optimal parameters of the ECM process providing attainment of specified blade quality parameters given in the design documentation, while providing maximal performance. The new technological methods suggested based on the results of the tests; in particular application of vibrating tool-electrodes and employment of locating elements made of high-strength materials, significantly extend the capabilities of this method.

  3. The effect of uncertainty of reactor parameters obtained using k0-NAA on result of analysis

    International Nuclear Information System (INIS)

    Sasajima, Fumio

    2006-01-01

    Neutron Activation Analysis using the k 0 method is a useful method allowing convenient and accurate simultaneous analysis of plural elements, eliminating the need for the use of comparative reference samples. As already well known, it is essential for the correct result of an analysis to obtain the α-factor and f-factor for a neutron spectrum in an irradiation field accurately when an attempt is made to use the k 0 method. For this reason, based on data obtained from the experiment conducted in the JRR-3 PN-3 system, how uncertainty of the measured values for α-factor and f-factor affects the result of an analysis was evaluated. The process of evaluation involved intentionally varying the values for reactor parameters followed by making an analysis of environmental reference samples (NIST SRM-1632c) using the k 0 method to examine the effect of these factors on the concentrations of 19 elements. The result of the evaluation revealed that the degree of the effect of uncertainty on the concentrations of 19 elements was at best approx. 1% under the condition of this experiment assuming that the factor α, a reactor parameter, had uncertainty of approx. 200%. (author)

  4. Leaching of Major and Minor Elements during the Transport and Storage of Coal Ash Obtained in Power Plant

    Directory of Open Access Journals (Sweden)

    Rada Krgović

    2014-01-01

    Full Text Available In power plant, coal ash obtained by combustion is mixed with river water and transported to the dump. Sequential extraction was used in order to assess pollution caused by leaching of elements during ash transport through the pipeline and in the storage (cassettes. A total of 80 samples of filter ash as well as the ash from active (currently filled and passive (previously filled cassettes were studied. Samples were extracted with distilled water, ammonium acetate, ammonium oxalate/oxalic acid, acidic solution of hydrogen-peroxide, and a hydrochloric acid. Concentrations of the several elements (Al, As, Cd, Co, Cu, Cr, Fe, Ba, Ca, Mg, Ni, Pb, and Zn in all extracts were determined by inductively coupled plasma atomic emission spectrometry. Pattern recognition method was carried out in order to provide better understanding of the nature of distribution of elements according to their origins. Results indicate possible leaching of As, Ca, Cd, Cu, Zn, and Pb. Among these elements As, Cd, and Pb are toxicologically the most important but they were not present in the first two phases with the exception of As. The leaching could be destructive and cause negative effects on plants, water pollution, and damage to some life forms.

  5. Results obtained with the passive radiation detectors in the ICCHIBAN-4 experiment

    International Nuclear Information System (INIS)

    Bilski, P.; Horwacik, T.

    2005-05-01

    In frame of the InterComparison of Cosmic rays with Heavy Ions Beams at NIRS (ICCHIBAN) organized at the HIMAC accelerator in Chiba several types of the thermoluminescent detectors (TLD), as well as CR-39 track detectors, were exposed. Four different types of TLDs were used: MTS-7 ( 7 LiF:Mg,Ti), MTS-6 ( 6 LiF:Mg,Ti), MCP-7 ( 7 LiF:Mg,Cu,P) and MTT-7 ( 7 LiF:Mg,Ti with changed activator composition. All TLDs were manufactured at the Institute of Nuclear Physics (INP) in Cracow. The detectors were irradiated with various doses of He, C, Ne and Fe ions. Part of exposures were done in unknown conditions, to test measuring capabilities of the detectors. For analyses of these results, the method of obtaining information on ionisation density of an unknown radiation field, which is based on ratios of responses of different LiF detectors, was successfully used. (author)

  6. Experimental Results Obtained with Air Liquide Cold Compression System CERN LHC and SNS Projects

    CERN Document Server

    Delcayre, F; Hamber, F; Hilbert, B; Monneret, E; Toia, J L

    2006-01-01

    Large scale collider facilities will make intensive use of superconducting magnets, operating below 2.0 K. This dictates high‐capacity refrigeration systems operating below 2.0 K. These systems, making use of cryogenic centrifugal compressors in a series arrangement with room temperature screw compressors will be coupled to a refrigerator, providing a certain power at 4.5 K. A first Air Liquide Cold Compression System (CCS) unit was built and delivered to CERN in 2001. Installed at the beginning of 2002, it was commissioned and tested successfully during year 2002. A series of four sets of identical CCS were then tested in 2004. Another set of four cryogenic centrifugal compressors (CCC) has been delivered to Thomas Jefferson National Accelerator Facility (JLAB) for the Spallation Neutron Source (SNS) in 2002. These compressors were tested and commissioned from December 2004 to July 2005. The experimental results obtained with these systems will be presented and discussed: the characteristics of the CCC wil...

  7. First results obtained from the Cello liquid argon end cap calorimeters

    International Nuclear Information System (INIS)

    Le Diberder, F.

    1981-05-01

    The Cello liquid argon calorimeter is presented in the first part of this thesis. The cryogenic system has to supply three cryostats filled with liquid argon: one cylindrical cryostat of 25 m 3 volume contains 2x8 separate modules; each of the two symmetric end cap cryostats contains two half cylindrical modules. Each module in the end cap part consists of 42 layers of lead strips interleaved with 43 full plates. The strips are alternatively vertical, horizontal and circular. In front of the lead calorimeter are 4 planes of copper foils glued on epoxy for dE/dx measurement. The electronics, signal processing and data acquisition system are described. In the second part, the performance and analysis of data measured by the end cap calorimeters are reported: study of Bhabha scattering e + e - → e + e - ; preliminary results obtained in two photon physics e + e - → e + e - γγ → e + e - X [fr

  8. Report of test and research results on atomic energy obtained in national institutes in fiscal 1985

    International Nuclear Information System (INIS)

    1986-01-01

    As for the test and research on the utilization of atomic energy in national institutes, the budget was appropriated for the first time in fiscal year 1956, and since then, the many valuable results of research have been obtained so far in the diversified fields of nuclear fusion, safety research, the irradiation of foods, medicine and others, thus the test and research accomplished the large role for promoting the utilization of atomic energy in Japan. In this report, the gists of the results of the test and research on the utilization of atomic energy carried out by national institutes in fiscal year 1985 are collected. No.1 of this report was published in 1960, and this is No.26. It is desired to increase the understanding about the recent trend and the results of the test and research on atomic energy utilization with this book. The researches on nuclear fusion, engineering safety and environmental radioactivity safety, the irradiation of foods, the countermeasures against cancer, fertilized soil, the quality improvement of brewing and farm products, the protection of farm products and the improvement of breeding, diagnosis and medical treatment, pharmaceuticals, environmental hygiene, the application to physiology and pathology, radiochemistry, radiation measurement, process analysis, nuclear reactor materials, nuclear powered ships, civil engineering, radioactivation analysis and injury prevention are reported. (Kako, I.)

  9. Summary of personal neutron dosemeter results obtained within the EVIDOS project

    International Nuclear Information System (INIS)

    Luszik-Bhadra, M.; Reginatto, M.; Schuhmacher, H.; Bolognese-Milsztajn, T.; Lacoste, V.; Boschung, M.; Fiechtner, A.; Coeck, M.; Vanhavere, F.; Curzio, G.; Errico d', F.; Kylloenen, J.-E.; Lindborg, L.; Bartlett, D.; Tanner, R.

    2005-01-01

    Full text: Within the EC project EVIDOS ('Evaluation of Individual Dosimetry in Mixed Neutron and Photon Radiation Fields'), different types of neutron personal dosemeters were irradiated in workplace fields in nuclear installations in Europe. Mostly electronic personal neutron dosemeters were tested, among them commercial devices (Thermo Electron EPD-N, Aloka PDM-313), devices from first industrial prototype series (Thermo Electron EPD-N2, Saphydose-n) and laboratory prototypes which were already in the stage of lightweight battery-operated instruments (PTB DOS-2002). In addition, dosemeters with (almost) immediate readout (BTI bubble detectors, Rados DIS-N) and passive dosemeters which needed no fielddependent calibration factors (PADC track detectors from PSI and NRPB) were used, as well as those TLD albedo dosemeters which are routinely used in the facilities visited. The results of measurements obtained within the EVIDOS project in workplace fields in nuclear installations in Europe, i.e. at Kruemmel (boiling water reactor, transport cask), at Mol (Venus research reactor, fuel facility Belgonucleaire) and at Ringhals (pressurized water reactor, transport cask) are presented and compared to reference values of personal dose equivalent H p (10) determined by means of Bonner spheres and novel directional spectrometers. In fields with strong back-scatter and moderation of neutrons, several dosemeters showed overreadings by more than a factor of two. In strongly directed fields with neutron dose equivalent peaked at about 1 MeV (MOX fuel), the same dosemeters showed under-readings of about a factor of two. These under- and over-readings in the workplace fields can be explained in terms of the dosemeter response functions for mono-energetic neutrons, which show over-responses in the thermal and intermediate neutron energy region and under-responses at about 1 MeV neutron energy. The dosemeter readings obtained in the workplace fields were checked for consistency by

  10. Experimental results obtained with the simulated cold moderator system. System characteristics and technical issues

    CERN Document Server

    Aso, T; Hino, R; Kaminaga, M; Kinoshita, H; Takahashi, T

    2002-01-01

    The Japan Atomic Energy Research Institute and the High Energy Accelerator Research Organization have been developing a Mega-Watt scale spallation target system. In the system, neutrons generated in a target are sorted out their energy to the proper values in liquid-hydrogen moderators. Then, the liquid-hydrogen is forced to circulate in order to suppress hydrogen temperature increase. In the operation of moderators, it is very important to establish a safety protection system against emergency shutdown of the accelerator or accidents of the cold moderator system. In order to obtain a technical data for design and safety review of the liquid-hydrogen system, we have fabricated an experimental apparatus simulated the cold moderator system using liquid nitrogen (max. 1.5 MPa, mini. 77 K) instead of liquid hydrogen. The experiments on a controllability of the system were carried out to investigate dynamic characteristics of the system. This report presents the experimental results and technical issues for the co...

  11. Experimental Results Obtained with Air Liquide Cold Compression System: CERN LHC and SNS Projects

    Science.gov (United States)

    Delcayre, F.; Courty, J.-C.; Hamber, F.; Hilbert, B.; Monneret, E.; Toia, J.-L.

    2006-04-01

    Large scale collider facilities will make intensive use of superconducting magnets, operating below 2.0 K. This dictates high-capacity refrigeration systems operating below 2.0 K. These systems, making use of cryogenic centrifugal compressors in a series arrangement with room temperature screw compressors will be coupled to a refrigerator, providing a certain power at 4.5 K. A first Air Liquide Cold Compression System (CCS) unit was built and delivered to CERN in 2001. Installed at the beginning of 2002, it was commissioned and tested successfully during year 2002. A series of four sets of identical CCS were then tested in 2004. Another set of four cryogenic centrifugal compressors (CCC) has been delivered to Thomas Jefferson National Accelerator Facility (JLAB) for the Spallation Neutron Source (SNS) in 2002. These compressors were tested and commissioned from December 2004 to July 2005. The experimental results obtained with these systems will be presented and discussed: the characteristics of the CCC will be detailed. The principles of control for the CCC in series will be detailed.

  12. The results obtained by INR-Pitesti to an international in-situ intercomparison exercise

    International Nuclear Information System (INIS)

    Dobrin, Relu; Dulama, Cristian; Toma, Alexandru

    2008-01-01

    Full text: The determination of soil contamination, dose rate measurements and in-situ gamma spectrometry are well established and widely used measurement procedures, especially after large scale nuclear incidents. To support decision makers and first responders with a more comprehensive and accurate overview immediately after a large scale nuclear or radiological emergency, as releases from a nuclear power plant or a terrorist attack with a dirty bomb, a fast and clear presentation of measurement data is indispensable. In 2007, the Austrian Research Centers GmbH - ARC (Seibersdorf) in cooperation with IAEA and the Austrian NBC Defense School organized an international measurement campaign, 'In-Situ Intercomparison Scenario' ISIS 2007, with the focus on In-Situ Gamma Spectrometry and Dose Rate Measurements in Emergency Situations. 56 teams from 25 countries, worldwide, took part to this exercise. The only Romanian team was 'CROWN'. The CROWN Laboratory is part of the Radiation Protection Laboratory of the Institute for Nuclear Research - Pitesti, certified for characterization of radioactive wastes and nuclear materials. The paper presents results obtained during different tasks of the exercise: 'Dose rate mapping'; 'Localization - Drive by'; 'Simulation of a contamination'; 'Identification Shielded; 'Identification/Quantification'; 'Buried sources; 'Environmental measurement'. (authors)

  13. Experimental results obtained with the simulated cold moderator system. System characteristics and technical issues

    Energy Technology Data Exchange (ETDEWEB)

    Aso, Tomokazu; Kaminaga, Masanori; Haga, Katsuhiro; Kinoshita, Hidetaka; Takahashi, Toshio; Hino, Ryutaro [Japan Atomic Energy Research Inst., Tokai, Ibaraki (Japan). Tokai Research Establishment

    2002-12-01

    The Japan Atomic Energy Research Institute and the High Energy Accelerator Research Organization have been developing a Mega-Watt scale spallation target system. In the system, neutrons generated in a target are sorted out their energy to the proper values in liquid-hydrogen moderators. Then, the liquid-hydrogen is forced to circulate in order to suppress hydrogen temperature increase. In the operation of moderators, it is very important to establish a safety protection system against emergency shutdown of the accelerator or accidents of the cold moderator system. In order to obtain a technical data for design and safety review of the liquid-hydrogen system, we have fabricated an experimental apparatus simulated the cold moderator system using liquid nitrogen (max. 1.5 MPa, mini. 77 K) instead of liquid hydrogen. The experiments on a controllability of the system were carried out to investigate dynamic characteristics of the system. This report presents the experimental results and technical issues for the construction of a practical liquid-hydrogen moderator system of the Mega-Watt scale target system. (author)

  14. Preliminary observations and results obtained with the ultraviolet spectrometer and polarimeter

    International Nuclear Information System (INIS)

    Tandberg-Hanssen, E.; Athay, R.G.; Beckers, J.M.; Brandt, J.C.; Bruner, E.C.; Chapman, R.D.; Cheng, C.C.; Burman, J.G.; Henze, W.; Hyder, C.L.; Michalitsianos, A.G.; Shine, R.A.; Schoolman, S.A.; Woodgate, B.E.

    1981-01-01

    We present new observations with the Ultraviolet Spectrometer and Polarimeter (UVSP) of a number of manifestations of solar activity obtained during the first 3 months of Solar Maximum Mission operations

  15. Rotation technique for irradiation of the bladder and the results obtained

    Energy Technology Data Exchange (ETDEWEB)

    Backhouse, T W [Coventry and Warwickshire Hospital (UK). Dept. of Radiotherapy and Oncology

    1979-05-01

    An argument is advanced for the use of partial rotational techniques for the treatment of carcinoma of the bladder. One hundred and seventy cases are analysed; the majority were T3 solid transitional cell lesions with an overall (corrected) survival rate of 24.7%. Salvage cystectomy produced a four-year survival rate of 40% when performed within six months of the radiotherapy.

  16. Preliminary observations and results obtained with the ultraviolet spectrometer and polarimeter. [for Solar Maximum Mission

    Science.gov (United States)

    Tandberg-Hassen, E.; Cheng, C. C.; Athay, R. G.; Beckers, J. M.; Brandt, J. C.; Chapman, R. D.; Bruner, E. C.; Henze, W.; Hyder, C. L.; Gurman, J. B.

    1981-01-01

    New observation with the Ultraviolet Spectrometer and Polarimeter (UVSP) of a number of manifestations of solar activity obtained during the first three months of Solar Maximum Mission operations are presented. Attention is given to polarimetry in sunspots, oscillations above sunspots, density diagnostics of transition-zone plasmas in active regions, and the eruptive prominence - coronal transient link.

  17. Analysis of results obtained from field tracing test under natural rain condition

    International Nuclear Information System (INIS)

    Mukai, M.; Kamiyama, H.; Tanaka, T.; Wang Zhiming; Zhao Yingjie; Li Zhengtang

    1993-01-01

    As one of the tests arranged by the cooperative research between CIRP and JAERI, field tracing tests using 3 H, 60 Co, 85 Sr and 134 Cs were conducted in pits at the CIRP's field test site located on a loess tableland under natural rain condition. Precipitation amount and evaporation rate were measured to study complicated spatial-temporal behavior of soil water movement under that condition. The evaporation rate was obtained through an analysis on the measured data by a combined method of heat balance and eddy correlation. Numerical model, that is based on piston flow assumption of soil water movement, was developed and applied to determine the behavior of the soil water movement in the pits. Using the determined water movement, 3 H migration was evaluated by numerical simulation. Change of 3 H distribution as a function of elapsed time as well explained by careful evaluation of the soil water movement that carried out before the analysis. (5 figs.)

  18. Preliminary Results from Duplex Procedure for Obtain of Fe Based Materials for Automotive Applications

    Science.gov (United States)

    Crăciun, R. C.; Stanciu, S.; Geantă, V.; Voiculescu, I.; Manole, V.; Gârneţ, I. A.; Alexandru, A.; Cimpoesu, N.; Săndulache, F.

    2017-06-01

    Abstract Iron based materials still represent a high percentage from metallic materials used in industry, in general, and in automotive industry, in particular. In this case we used a duplex process in order to obtain the FeMnSiAl experimental alloy for a more efficient use of various units. In the first stage iron, manganese, silicon and aluminum were melted and mixed together using arc melting technology and for the second stage the alloy was re-melt for homogeneity in an induction furnace. Chemical composition, after each melting step, was analyzed using EDS Bruker detector for various areas and microstructural characterization using SEM, VegaTescan LMH II with SE detector, equipment. This alloy is proposed as a metallic approach of mechanical dumpers used in automotive industry for low and medium impact contacts.

  19. Vehicle Animation Software (VAS) to Animate Results Obtained from Vehicle Handling and Rollover Simulations and Tests

    Science.gov (United States)

    1991-04-01

    Results from vehicle computer simulations usually take the form of numeric data or graphs. While these graphs provide the investigator with the insight into vehicle behavior, it may be difficult to use these graphs to assess complex vehicle motion. C...

  20. Occupational radioprotection program at Nuclear Engineering Institute -IEN: results obtained in 1991

    International Nuclear Information System (INIS)

    Fajardo, P.W.; Pastura, V.F.S.; Soares, M.L.; LeRoy, C.L.; Teixeira, M.V.; Santos, I.H.T.; Pujol Filho, S.V.

    1992-01-01

    The results of occupational radioprotection program at Nuclear Engineering Institute-IEN- in 1991 are presented. The personnel monitoring, the routine monitoring of limited areas, the operational monitoring during the operation and the cyclotron CV-28 maintenance, the radioisotope processing and Argonauta Reactor operation, the control of radioprotection equipment and the control of radiation sources are included. (C.G.C.)

  1. Alecto - results obtained with homogeneous critical experiments on plutonium 239, uranium 235 and uranium 233

    International Nuclear Information System (INIS)

    Bruna, J.G.; Brunet, J.P.; Caizegues, R.; Clouet d'Orval, Ch.; Kremser, J.; Tellier, H.; Verriere, Ph.

    1965-01-01

    In this report are given the results of the homogeneous critical experiments ALECTO, made on plutonium 239, uranium 235 and uranium 233. After a brief description of the equipment, the critical masses for cylinders of diameters varying from 25 to 42 cm, are given and compared with other values (foreign results, criticality guide). With respect to the specific conditions of neutron reflection in the ALECTO experiments the minimal values of critical masses are: Pu239 M c = 910 ± 10 g, U235 M c = 1180 ± 12 g and U233 M c = 960 ± 10 g. Experiments relating to cross sections and constants to be used on these materials are presented. Lastly, kinetic experiments allow to compare pulsed neutron methods to fluctuation methods [fr

  2. Macromolecular crystallographic results obtained using a 2048x2048 CCD detector at CHESS

    International Nuclear Information System (INIS)

    Thiel, D.J.; Ealick, S.E.; Tate, M.W.; Gruner, S.M.; Eikenberry, E.F.

    1996-01-01

    We present results of macromolecular crystallographic experiments performed at the Cornell High Energy Synchrotron Source (CHESS) with a new CCD-based detector. This detector, installed in January 1995, complements a 1024x1024 CCD detector that has been in continuous operation at CHESS since December 1993. The new detector is based on a 4-port, 2048x2048 pixel CCD that is directly coupled to a Gd 2 O 2 S:Tb phosphor by a 3:1 tapered fiber optic. The active area of the phosphor is a square 82 mm on an edge. The readout time is 7 seconds. In the standard mode of operation, the pixel size at the active area is 41 μm on the edge leading to the capability of resolving approximately 200 orders of diffraction across the detector face. The detector also operates in a 1024x1024 mode in which the pixel size is electronically increased by a factor of 4 in area resulting in smaller data files and faster detector readout but at the expense of spatial resolution. Most of the data that has been collected by this detector has been collected in this mode. Dozens of data sets have been collected by many experimenters using this detector at CHESS during the four month period from its installation until the start of the six-month down period of the storage ring. The capabilities of the detector will be illustrated with results from various crystallographic measurements including experiments in which the recorded diffraction patterns extend in resolution as far as 1 A. The results demonstrate that this detector is capable of collecting data of quality at least equal to that of imaging plates but, in many circumstances, with much greater beamline efficiency. copyright 1996 American Institute of Physics

  3. Irradiation devices for fusion reactor materials results obtained from irradiated lithium aluminate at the OSIRIS reactor

    International Nuclear Information System (INIS)

    Lefevre, F.; Thevenot, G.; Rasneur, B.; Botter, F.

    1986-06-01

    Studies about controlled fusion reactor of the Tokamak type require the examination of the radiation effects on the behaviour of various potential materials. Thus, in the first part of this paper, are presented the devices adapted to these materials studies and used in the OSIRIS reactor. In a second part, is described an experiment of irradiation ceramics used as candidates for breeding material and are given the first results

  4. Report of test and research results on atomic energy obtained in national institutes in fiscal 1987

    International Nuclear Information System (INIS)

    1989-01-01

    The test and research regarding the utilization of atomic energy carried out in national institutions have produced many valuable results in diverse fields so far, such as nuclear fusion, safety research, food irradiation and medicine, since the budget had been appropriated for the first time in 1956. It has accomplished large role in the promotion of atomic energy utilization in Japan. This report is volume 28, in which the results of the test and research on atomic energy utilization carried out by national institutions in fiscal year 1987 are summarized. It is hoped that the understanding about the recent trend and the results of the test and research on atomic energy utilization is further promoted by this report. The contents of this report are nuclear fusion; the research on engineering safety and environmental radioactivity safety; food irradiation; the countermeasures against cancer; fertilized soil, the improvement of quality, the protection of plants and the improvement of breeding in agriculture and fishery fields; diagnosis and medical treatment, pharmaceuticals, environmental hygiene and the application to physiology and pathology in medical field; radiation measurement and process analysis in mining and industry fields; nuclear reactor materials and nuclear-powered ships; civil engineering; radioactivation analysis; the research on the prevention of injuries; and the basic researches on materials and acessment and reduction of irradiation risk. (J.P.N.)

  5. Report of test and research results on atomic energy obtained in national institutes in fiscal 1986

    International Nuclear Information System (INIS)

    1988-01-01

    The test and research regarding the utilization of atomic energy carried out in national institutions have produced many valuable results in diverse fields so far, such as nuclear fusion, safety research, food irradiation and medicine, since the budget had been appropriated for the first time in 1956. It has accomplished large role in the promotion of atomic energy utilization in Japan. This report is volume 27, in which the results of the test and research on atomic energy utilization carried out by national institutions in fiscal year 1986 are summarized. It is hoped that the understanding about the recent trend and the results of the test and research on atomic energy utilization is further promoted by this report. The contents of this report are nuclear fusion; the research on engineering safety and environmental radioactivity safety; food irradiation; the countermeasures against cancer; fertilized soil, the improvement of quality, the protection of plants and the improvement of breeding in agriculture and fishery fields; diagnosis and medical treatment, pharmaceuticals, environmental hygiene and the application to physiology and pathology in medical field; radiation chemistry and radiation measurement in mining and industry fields; nuclear reactor materials and nuclear-powered ships; civil engineering; radioactivation analysis; and the research on the prevention of injuries. (Kako, I.)

  6. Report of test and research results on atomic energy obtained in national institutes in fiscal 1984

    International Nuclear Information System (INIS)

    1985-01-01

    The test and research regarding the utilization of atomic energy carried out in national institutions have produced many valuable results in diverse fields so far, such as nuclear fusion, safety research, food irradiation and medicine, since the budget had been appropriated for the first time in 1956. It has accomplished large role in the promotion of atomic energy utilization in Japan. This report is Volume 25, in which the results of the test and research on atomic energy utilization carried out by national institutions in fiscal year 1984 are summarized. It is hoped that the understanding about the recent trend and the results of the test and research on atomic energy utilization is further promoted by this report. The contents of this report are nuclear fusion; the research on engineering safety and environmental radioactivity safety; food irradiation; the countermeasures against cancer; fertilized soil, the improvement of quality, the protection of plants and the improvement of breeding in agriculture and fishery fields; diagnosis and medical treatment, pharmaceuticals, environmental hygiene and the application to physiology and pathology in medical field; radiation chemistry and radiation measurement in mining and industry fields; nuclear reactor materials and nuclear-powered ships; civil engineering; radioactivation analysis; and the research on the prevention of injuries. (Kako, I.)

  7. Radon in Estonian buildings. Establishment of a measurement system and obtained results

    International Nuclear Information System (INIS)

    Pahapill, L.; Rulkov, A.; Swedjemark, G.A.

    1996-12-01

    One purpose of this project was the establishment of a radon monitoring programme inside the state environmental monitoring programme. Another purpose was to investigate regions, expected to have high radon levels indoors. A new method for the long-term measurement of indoor radon was established and the staff for these measurements was trained. The results of the measurement can be used by Estonian decision-makers to work out rules and standards. There is no legislative act in the field of radiation in Estonian at this time. To summarize the results of the measurements we can say that indoor radon concentrations vary by region. The radon investigations must be continued to identify the risk areas and types of housing construction. The results of the state radon monitoring are provided to the municipalities, who advice the owners of planned new houses to select the right construction for the house. A new project will follow with an investigation of radon in randomly selected dwellings, training and equipment for radon measurement in soil, and general advice with regard to radon, as well as assistance in preparing information about radon. 7 refs, 5 figs

  8. Experimental results on advanced inertial fusion schemes obtained within the HiPER project

    International Nuclear Information System (INIS)

    Batani, Dimitri; Santos, Jorge J.; Schurtz, Guy; Hulin, Sebastien; Ribeyre, Xavier; Nicolai, Philippe; Vauzour, Benjamin; Dorchies, Fabien; Gizzi, Leonida A.; Koester, Petra; Labate, Luca; Honrubia, Javier; Antonelli, Luca; Morace, Alessio; Volpe, Luca; Nazarov, Wiger; Pasley, John; Richetta, Maria; Lancaster, Kate; Spindloe, Christopher; Tolley, Martin; Neely, David; Kozlova, Michaela; Nejdl, Jaroslav; Rus, Bedrich; Wolowski, Jerzy; Badziak, Jan

    2012-01-01

    This paper presents the results of experiments conducted within the Work Package 10 (fusion experimental programme) of the HiPER project. The aim of these experiments was to study the physics relevant for advanced ignition schemes for inertial confinement fusion, i.e. the fast ignition and the shock ignition. Such schemes allow to achieve a higher fusion gain compared to the indirect drive approach adopted in the National Ignition Facility in United States, which is important for the future inertial fusion energy reactors and for realising the inertial fusion with smaller facilities. (authors)

  9. Using the Viking biology experimental results to obtain chemical information about Martian regolith

    Science.gov (United States)

    Plumb, Robert C.

    1992-01-01

    Although initially formulated as biology experiments, most of the results produced by the Viking Labeled Release (LR), Gas Exchange (GEX), and Pyrolytic Release (PR) experiments have been reproduced by chemical means. The experiments do not need more study as 'biological' phenomena, but they do deserve much more careful consideration from a chemical viewpoint. They are the only 'wet-chemical' experiments that scientists have performed on another planet, but they have not found very general use as sources of scientific information. There is a large set of potentially useful chemical observations, e.g., the three resolvable and precisely measured kinetic components of the release of C-14-labeled gases, the thermal sensitivity and magnitudes of the oxidation reaction(s) of the LR experiments, the kinetics and magnitude of the O2 and CO2 release of the GEX experiments, the thermal sensitivity of the GEX results, the differences between the thermal sensitivity of the GEX and the thermal sensitivity of the LR responses, and the kinetics and magnitudes of the LR successive injection reabsorption effect. It should be possible to test many chemical aspects of hypothetical martian phenomena in experiments using the biology experimental configurations and derive much valuable information by comparisons with the Viking observations.

  10. Report of test and research results on atomic energy obtained in national institutes in fiscal 1990

    International Nuclear Information System (INIS)

    1991-01-01

    The tests and researches on the development and utilization of atomic energy in national laboratories were begun in 1956, and have accomplished the great role for the advance of the development and utilization of atomic energy in Japan by having produced many valuable results so far. Atomic energy has been utilized in diverse fields, and also in national laboratories, the research for expanding the development and utilization of atomic energy in food irradiation, medicine, agriculture, forestry, fishery and others in addition to the basic research on nuclear fusion and safety have been advanced. Further expecting the pervasive effect to general science and technology, the development of basic technology and integrated research are promoted from the viewpoint of new techical innovation and creative technology. This is 31st report in which the results of the tests and researches carried out by national laboratories in fiscal year 1990 are summarized. Nuclear fusion, safety research, food irradiation, cancer countermeasures, agriculture, forestry, fishery, medicine, mining and manufacture, power utilization, construction, radioactivation analysis and so on were the main subjects. (K.I.)

  11. Report of test and research results on atomic energy obtained in national institutes in fiscal 1982

    International Nuclear Information System (INIS)

    1983-01-01

    As for the test and research on the utilization of atomic energy by national organizations, the budget was appropriated for the first time in fiscal year 1956. Since then, many valuable results of research have been produced in the diverse fields of nuclear fusion, safety research, food irradiation, medicine and others, in this way, the test and research have played large roles in the promotion of the utilization of atomic energy in Japan. This is the 23rd report, in which the results of the test and research on the utilization of atomic energy carried out in fiscal year 1982 by national organizations are summarized. 5 researches on nuclear fusion, 12 researches on engineering safety, 5 researches on environmental radioactivity safety, 3 researches on food irradiation, 5 researches on the countermeasures to cancer, 8 researches on soil fertilization, 4 researches on quality improvement, 7 researches on crop protection, 5 researches on the improvement of breeding, 8 researches on diagnosis and treatment, 8 researches on pharmaceuticals, 10 researches on the application to pathology, 6 researches on mining and industry, 6 researches on power reactors and nuclear ships, 1 research on underground water, 6 researches on activation analysis and 3 researches on injury prevention are reported. (Kako, I.)

  12. Report of test and research results on atomic energy obtained in national institutes in fiscal 1983

    International Nuclear Information System (INIS)

    1984-01-01

    As for the test and research on the utilization of atomic energy by national organizations, the budget was appropriated for the first time in fiscal year 1956. Since then, many valuable results of research have been produced in the diverse fields of nuclear fusion, safety research, food irradiation, medicine and others, in this way, the test and research have played large roles in the promotion of the utilization of atomic energy in Japan. This is the 24th report, in which the results of the test and research on the utilization of atomic energy carried out in fiscal year 1983 by national organizations are summarized. 5 researches on nuclear fusion, 19 researches on engineering safety and environmental radioactivity safety, 3 researches on food irradiation, 6 researches on the countermeasures to cancer, 19 researches on agriculture, forestry and fishery, 30 researches on medicine, pharmaceuticals and environmental hygiene, 6 researches on mining and industry, 6 researches on power reactors and nuclear ships, 1 research on agricultural water, 7 researches on activation analysis and 4 researches on injury prevention are reported. (Kako, I.)

  13. Aircrew Exposure To Cosmic Radiation Evaluated By Means Of Several Methods; Results Obtained In 2006

    International Nuclear Information System (INIS)

    Ploc, Ondrej; Spurny, Frantisek; Jadrnickova, Iva; Turek, Karel

    2008-01-01

    Routine evaluation of aircraft crew exposure to cosmic radiation in the Czech Republic is performed by means of calculation method. Measurements onboard aircraft work as a control tool of the routine method, as well as a possibility of comparison of results measured by means of several methods. The following methods were used in 2006: (1) mobile dosimetry unit (MDU) type Liulin--a spectrometer of energy deposited in Si-detector; (2) two types of LET spectrometers based on the chemically etched track detectors (TED); (3) two types of thermoluminescent detectors; and (4) two calculation methods. MDU represents currently one of the most reliable equipments for evaluation of the aircraft crew exposure to cosmic radiation. It is an active device which measures total energy depositions (E dep ) in the semiconductor unit, and, after appropriate calibration, is able to give a separate estimation for non-neutron and neutron-like components of H*(10). This contribution consists mostly of results acquired by means of this equipment; measurements with passive detectors and calculations are mentioned because of comparison. Reasonably good agreement of all data sets could be stated

  14. Report of test and research results on atomic energy obtained in national institutes in fiscal 1992

    International Nuclear Information System (INIS)

    1994-01-01

    The tests and researches on the development and utilization of atomic energy in national laboratories were begun in 1956, and have accomplished the great role for the advance of the development and utilization of atomic energy in Japan by having produced many valuable results so far. Atomic energy has been utilized not only in the field of nuclear power but also in diverse fields, and in national laboratories, the research for expanding the development and utilization of atomic energy in medicine, agriculture, forestry, fishery, radioactivation analysis and others in addition the basic research on nuclear fusion have been advanced. Further expecting the pervasive effect to general science and technology, the development of integrated research are promoted from the viewpoint of new technical innovation and creative technology. The safety research of nuclear facilities have been carried out to keep them high level on the basis of the yearly program enacted by Nuclear Safety Commission. This is the report No. 33, in which the results of the test and research in the fields of nuclear fusion safety research, food irradiation, cancer countermeasures, agriculture, forestry, fishery, medicine, mining and manufacture, power utilization, construction, radioactivation analysis carried on in fiscal 1992 are summarized. (J.P.N.)

  15. Operating results obtained in a nuclear power plant with a sensor surveillance prototype

    International Nuclear Information System (INIS)

    Jacquot, J.P.; Poujol, A.; Beaubatie, J.; Ciaramitaro, W.

    1983-03-01

    Surveillance methods have been validated and specific equipment have been built to measure the response time of sensors from a nuclear power plant protection channel. The reason of the choice of this parameter is twofold: the sensor response time is representative of the sensor physical status and is also part of the overall channel response time. Two surveillance methods are used: noise analysis (by AR or PSD modeling), and loop current step response (for resistance thermometer detectors only). The methods were validated on test facilities and on nuclear power plants. Two test equipments were built and tested on plants. Results are represented and conclusions are drawn on the feasibility of such methods for sensor surveillance [fr

  16. 2D and 3D core-collapse supernovae simulation results obtained with the CHIMERA code

    Energy Technology Data Exchange (ETDEWEB)

    Bruenn, S W; Marronetti, P; Dirk, C J [Physics Department, Florida Atlantic University, 777 W. Glades Road, Boca Raton, FL 33431-0991 (United States); Mezzacappa, A; Hix, W R [Physics Division, Oak Ridge National Laboratory, Oak Ridge, TN 37831-6354 (United States); Blondin, J M [Department of Physics, North Carolina State University, Raleigh, NC 27695-8202 (United States); Messer, O E B [Center for Computational Sciences, Oak Ridge National Laboratory, Oak Ridge, TN 37831-6354 (United States); Yoshida, S, E-mail: bruenn@fau.ed [Max-Planck-Institut fur Gravitationsphysik, Albert Einstein Institut, Golm (Germany)

    2009-07-01

    Much progress in realistic modeling of core-collapse supernovae has occurred recently through the availability of multi-teraflop machines and the increasing sophistication of supernova codes. These improvements are enabling simulations with enough realism that the explosion mechanism, long a mystery, may soon be delineated. We briefly describe the CHIMERA code, a supernova code we have developed to simulate core-collapse supernovae in 1, 2, and 3 spatial dimensions. We then describe the results of an ongoing suite of 2D simulations initiated from a 12, 15, 20, and 25 M{sub o-dot} progenitor. These have all exhibited explosions and are currently in the expanding phase with the shock at between 5,000 and 20,000 km. We also briefly describe an ongoing simulation in 3 spatial dimensions initiated from the 15 M{sub o-dot} progenitor.

  17. THE ANALYSIS OF SEVERAL RESULTS OBTAINED BY ROMANIA IN THE FIELD OF SUSTAINABLE TRANSPORT

    Directory of Open Access Journals (Sweden)

    Perțicaș Diana Claudia

    2015-07-01

    Full Text Available We know that between the transport sector and all other branches of economy there is a strong interdependence link but also between it and the surrounding environment, being one of the most polluting sectors of activity. Transport is considered a primary field in any national economy development context, especially if we take into account its interdependence with other branches of national economy. Developing of transports also includes improving road, rail, river and sea services, as well as air transports. The objectives of the EU aim especially to modernize the transport infrastructures, be them by road, ship or by air, which would result in increasing the speed of freight transport, fluidizing traffic, attracting new foreign investors in various areas, accelerating the renewal of the auto park and decommissioning morally and physically worn vehicles which are extremely pollutant, the revival of maritime transports through Romanian ports, progressive completion of imposed performances through standards and regulations on the transport market, etc. All these objectives have as a main purpose the reducing of energy consumption, reducing transport costs as well as increasing competition in the national transport system.The development of transport has the role of stimulating public transport services and to guarantee a minimum general accessibility to public services for all citizens. Children, the elderly, disabled people or other vulnerable categories of people are not and will not be forgotten, for which certain standards set by the European Union must be respected.The present paper wishes to analyze a part of the results, either positive or negative, in the field of transports, made by our country.

  18. Comparison of different scenarios for the deployment of fast reactors in France. Results obtained with COSI

    International Nuclear Information System (INIS)

    Coquelet-Pascal, Christine; Meyer, Maryan; Girieud, Richard

    2011-01-01

    In the frame of the French Act for waste management, scenarios studies are carried out with the simulation software COSI to compare different options of evolution of the French reactor fleet, possibilities of plutonium recycling, and options of separation and transmutation of minor actinides. The goal of these studies is to evaluate the sustainability of Sodium cooled Fast Reactors (SFR) deployment from plutonium availability viewpoint, as well as the interest of minor actinides transmutation options in SFR and associated impacts (decay heat and toxicity) on cycle facilities and geological storage. Each option has been evaluated separately in dynamic scenarios taking into account the transition between the current nuclear reactor fleet and a generation IV fleet, with the deployment of SFR in replacement of PWR. In this paper, the results of three types of scenarios, in the continuity of the paper of GLOBAL 2009, are discussed: 1 - plutonium recycling in SFR; 2 - plutonium recycling and minor actinides transmutation in SFR; 3 - plutonium recycling and americium transmutation in SFR. MA transmutation in heterogeneous mode (named 'het.') and in homogeneous mode (named 'hom.') are distinguished. By comparison with the previous paper, new scenarios and extended results are added and a global comparison between transmutation performances is done. Scenarios have been optimized to minimize the impacts on fuel cycle: stabilization of plants capacities over 40 years, limitation of minor actinides storage in the case of heterogeneous transmutation, limitation of MA content in the case of homogeneous transmutation. The impact of MA transmutation on decay heat of fresh and spent fuel are also assessed. The selected scenarios bring also elements on the impact of a SFR deployment delayed from 2040 to 2080, with or without MA transmutation, and the impact of an increase in the total power capacity installed by maximizing the SFR share in a symbiotic fleet PWR-SFR. Whatever the

  19. Gravity Changes and Internal Processes: Some Results Obtained from Observations at Three Volcanoes

    Science.gov (United States)

    Jentzsch, Gerhard; Weise, Adelheid; Rey, Carlos; Gerstenecker, Carl

    Temporal gravity changes provide information about mass and/or density variations within and below the volcano edifice. Three active volcanoes have been under investigation; each of them related to a plate boundary: Mayon/Luzon/Philippines, Merapi/Java/Indonesia, and Galeras/Colombia. The observed gravity changes are smaller than previously expected but significant. For the three volcanoes under investigation, and within the observation period, mainly the increase of gravity is observed, ranging from 1,000 nm-2 to 1,600 nms-2. Unexpectedly, the gravity increase is confined to a rather small area with radii of 5 to 8 km around the summit. At Mayon and Merapi the parallel GPS measurements yield no significant elevation changes. This is crucial for the interpretation, as the internal pressure variations do not lead to significant deformation at the surface. Thus the classical Mogi-model for a shallow extending magma reservoir cannot apply. To confine the possible models, the attraction due to changes of groundwater level or soil moisture is estimated along the slope of Merapi exemplarily by 2-D modelling. Mass redistribution or density changes were evaluated within the vent as well as deeper fluid processes to explain the gravity variations; the results are compared to the model incorporating the additional effect of elastic deformation.

  20. Development, calibration and experimental results obtained with an innovative calorimeter (CALMOS) for nuclear heating measurements

    International Nuclear Information System (INIS)

    Carcreff, H.; Cloute-Cazalaa, V.; Salmon, L.

    2011-01-01

    Nuclear heating inside an MTR reactor has to be known in order to be able to control samples temperature during irradiation experiments. An R and D program has been carried out at CEA to design a new type of in-core calorimetric system. This new development, started in 2002, has for main objective to manufacture a calorimeter suitable to monitoring nuclear heating inside the 70 MWth OSIRIS material testing reactor operated by CEA's Nuclear Energy Div. at the Saclay research center. An innovative calorimetric probe, associated to a specific handling system, has been designed to provide access to measurements both along the fissile height and on the upper part of the core, where nuclear heating still remains high. Two mock-ups of the probe were manufactured and tested in 2005 and 2009 in ex-core area of OSIRIS reactor for process validation, while a displacement system has been especially studied to move the probe along a given axial measurement range. This paper deals with the development, tests on preliminary mock-ups and the finalization of the probe. Main modeling and experimental results are presented. Moreover, alternative methods to calibration for nuclear heating rate measurements which are now possible with this new calorimeter are presented and discussed. (authors)

  1. Development, calibration, and experimental results obtained with an innovative calorimeter (CALMOS) for nuclear heating measurements

    International Nuclear Information System (INIS)

    Carcreff, Hubert; Cloute-Cazalaa, Veronique; Salmon, Laurent

    2012-01-01

    Nuclear heating inside an MTR reactor has to be known in order to be able to control samples temperature during irradiation experiments. An R and D program has been carried out at CEA to design a new type of in-core calorimetric system. This new development, started in 2002, has for main objective to manufacture a calorimeter suitable to monitoring nuclear heating inside the 70 MWth OSIRIS material testing reactor operated by CEA's Nuclear Energy Division at the Saclay research center. An innovative calorimetric probe, associated to a specific handling system, has been designed to provide access to measurements both along the fissile height and on the upper part of the core, where nuclear heating still remains high. Two mock-ups of the probe were manufactured and tested in 2005 and 2009 in ex-core area of OSIRIS reactor for process validation, while a displacement system has been especially studied to move the probe along a given axial measurement range. This paper deals with the development, tests on preliminary mock-ups and the finalization of the probe. Main modeling and experimental results are presented. Moreover, alternative methods to calibration for nuclear heating rate measurements which are now possible with this new calorimeter are presented and discussed. (authors)

  2. Preliminary physico-chemical results obtained on water using new data acquisition systems for deep wells

    International Nuclear Information System (INIS)

    Vinson, J.M.; Peyrus, J.C.

    1984-02-01

    Data acquisition systems recently developed in the context of research on deep storage facilities have provided with an initial set of interesting observations for the physico-chemical study of boreholes. It is possible to make correlations between the chemical compositions of water, pH and the nature of the substrate. The sampling done at Auriat with a Gerhardt-Owen probe shows the variability in the composition of water as a function of depth. The variation in calcium content, following that of pH, is particularly notable. Examination of pH measurements is of particular interest. A general gradient correlates exactly with the nature of the substrate. Whereas steel piping has a very alkaline pH, distinct pH values correspond to the two types of granite substrate. In this general gradient, series of disturbances can be seen which correspond perfectly to fracturation zones or large fractures. These most promising preliminary results lead to believe that in situ physico-chemical measurements should be continued and developed with a view to improved evaluation of the safety of deep storage facilities

  3. Latest results of SEE measurements obtained by the STRURED demonstrator ASIC

    Energy Technology Data Exchange (ETDEWEB)

    Candelori, A. [INFN, Section of Padova, Via Marzolo 8, c.a.p. 35131, Padova (Italy); De Robertis, G. [INFN Section of Bari, Via Orabona 4, c.a.p. 70126, Bari (Italy); Gabrielli, A. [Physics Department, University of Bologna, Viale Berti Pichat 6/2, c.a.p. 40127, Bologna (Italy); Mattiazzo, S.; Pantano, D. [INFN, Section of Padova, Via Marzolo 8, c.a.p. 35131, Padova (Italy); Ranieri, A., E-mail: antonio.ranieri@ba.infn.i [INFN Section of Bari, Via Orabona 4, c.a.p. 70126, Bari (Italy); Tessaro, M. [INFN, Section of Padova, Via Marzolo 8, c.a.p. 35131, Padova (Italy)

    2011-01-21

    With the perspective to develop a radiation-tolerant circuit for High Energy Physics (HEP) applications, a test digital ASIC VLSI chip, called STRURED, has been designed and fabricated using a standard-cell library of commercial 130 nm CMOS technology by implementing three different radiation-tolerant architectures (Hamming, Triple Modular Redundancy and Triple Time Redundancy) in order to correct circuit malfunctions induced by the occurrence of Soft Errors (SEs). SEs are one of the main reasons of failures affecting electronic digital circuits operating in harsh radiation environments, such as in experiments performed at HEP colliders or in apparatus to be operated in space. In this paper we present and discuss the latest results of SE cross-section measurements performed using the STRURED digital device, exposed to high energy heavy ions at the SIRAD irradiation facility of the INFN National Laboratories of Legnaro (Padova, Italy). In particular the different behaviors of the input part and the core of the three radiation-tolerant architectures are analyzed in detail.

  4. Multi-Grid detector for neutron spectroscopy: results obtained on time-of-flight spectrometer CNCS

    Science.gov (United States)

    Anastasopoulos, M.; Bebb, R.; Berry, K.; Birch, J.; Bryś, T.; Buffet, J.-C.; Clergeau, J.-F.; Deen, P. P.; Ehlers, G.; van Esch, P.; Everett, S. M.; Guerard, B.; Hall-Wilton, R.; Herwig, K.; Hultman, L.; Höglund, C.; Iruretagoiena, I.; Issa, F.; Jensen, J.; Khaplanov, A.; Kirstein, O.; Lopez Higuera, I.; Piscitelli, F.; Robinson, L.; Schmidt, S.; Stefanescu, I.

    2017-04-01

    The Multi-Grid detector technology has evolved from the proof-of-principle and characterisation stages. Here we report on the performance of the Multi-Grid detector, the MG.CNCS prototype, which has been installed and tested at the Cold Neutron Chopper Spectrometer, CNCS at SNS. This has allowed a side-by-side comparison to the performance of 3He detectors on an operational instrument. The demonstrator has an active area of 0.2 m2. It is specifically tailored to the specifications of CNCS. The detector was installed in June 2016 and has operated since then, collecting neutron scattering data in parallel to the He-3 detectors of CNCS. In this paper, we present a comprehensive analysis of this data, in particular on instrument energy resolution, rate capability, background and relative efficiency. Stability, gamma-ray and fast neutron sensitivity have also been investigated. The effect of scattering in the detector components has been measured and provides input to comparison for Monte Carlo simulations. All data is presented in comparison to that measured by the 3He detectors simultaneously, showing that all features recorded by one detector are also recorded by the other. The energy resolution matches closely. We find that the Multi-Grid is able to match the data collected by 3He, and see an indication of a considerable advantage in the count rate capability. Based on these results, we are confident that the Multi-Grid detector will be capable of producing high quality scientific data on chopper spectrometers utilising the unprecedented neutron flux of the ESS.

  5. Simbol-X Hard X-ray Focusing Mirrors: Results Obtained During the Phase A Study

    International Nuclear Information System (INIS)

    Tagliaferri, G.; Basso, S.; Civitani, M.; Conconi, P.; Cotroneo, V.; Pareschi, G.; Spiga, D.; Borghi, G.; Garoli, D.; Mattarello, V.; Orlandi, A.; Valsecchi, G.; Vernani, D.; Burkert, W.; Freyberg, M.; Hartner, G.; Citterio, O.; Gorenstein, P.; Romaine, S.

    2009-01-01

    Simbol-X will push grazing incidence imaging up to 80 keV, providing a strong improvement both in sensitivity and angular resolution compared to all instruments that have operated so far above 10 keV. The superb hard X-ray imaging capability will be guaranteed by a mirror module of 100 electroformed Nickel shells with a multilayer reflecting coating. Here we will describe the technogical development and solutions adopted for the fabrication of the mirror module, that must guarantee an Half Energy Width (HEW) better than 20 arcsec from 0.5 up to 30 keV and a goal of 40 arcsec at 60 keV. During the phase A, terminated at the end of 2008, we have developed three engineering models with two, two and three shells, respectively. The most critical aspects in the development of the Simbol-X mirrors are i) the production of the 100 mandrels with very good surface quality within the timeline of the mission, ii) the replication of shells that must be very thin (a factor of 2 thinner than those of XMM-Newton) and still have very good image quality up to 80 keV, iii) the development of an integration process that allows us to integrate these very thin mirrors maintaining their intrinsic good image quality. The Phase A study has shown that we can fabricate the mandrels with the needed quality and that we have developed a valid integration process. The shells that we have produced so far have a quite good image quality, e.g. HEW < or approx. 30 arcsec at 30 keV, and effective area. However, we still need to make some improvements to reach the requirements. We will briefly present these results and discuss the possible improvements that we will investigate during phase B.

  6. Simbol-X Hard X-ray Focusing Mirrors: Results Obtained During the Phase A Study

    Science.gov (United States)

    Tagliaferri, G.; Basso, S.; Borghi, G.; Burkert, W.; Citterio, O.; Civitani, M.; Conconi, P.; Cotroneo, V.; Freyberg, M.; Garoli, D.; Gorenstein, P.; Hartner, G.; Mattarello, V.; Orlandi, A.; Pareschi, G.; Romaine, S.; Spiga, D.; Valsecchi, G.; Vernani, D.

    2009-05-01

    Simbol-X will push grazing incidence imaging up to 80 keV, providing a strong improvement both in sensitivity and angular resolution compared to all instruments that have operated so far above 10 keV. The superb hard X-ray imaging capability will be guaranteed by a mirror module of 100 electroformed Nickel shells with a multilayer reflecting coating. Here we will describe the technogical development and solutions adopted for the fabrication of the mirror module, that must guarantee an Half Energy Width (HEW) better than 20 arcsec from 0.5 up to 30 keV and a goal of 40 arcsec at 60 keV. During the phase A, terminated at the end of 2008, we have developed three engineering models with two, two and three shells, respectively. The most critical aspects in the development of the Simbol-X mirrors are i) the production of the 100 mandrels with very good surface quality within the timeline of the mission, ii) the replication of shells that must be very thin (a factor of 2 thinner than those of XMM-Newton) and still have very good image quality up to 80 keV, iii) the development of an integration process that allows us to integrate these very thin mirrors maintaining their intrinsic good image quality. The Phase A study has shown that we can fabricate the mandrels with the needed quality and that we have developed a valid integration process. The shells that we have produced so far have a quite good image quality, e.g. HEW <~30 arcsec at 30 keV, and effective area. However, we still need to make some improvements to reach the requirements. We will briefly present these results and discuss the possible improvements that we will investigate during phase B.

  7. Comparison of NDT techniques to evaluate CFRP. Results obtained in a MAIzfp round robin test

    Energy Technology Data Exchange (ETDEWEB)

    Grosse, Christian U. [Technische Univ. Muenchen (Germany). Chair of Non-destructive Testing; Goldammer, Matthias; Grager, Jan-Carl [Siemens AG Corporate Technology, Muenchen (Germany); and others

    2016-10-01

    Fiber reinforced polymeric materials are used for lightweight constructions and are an integral part of cars, airplanes or rotor blades of wind turbines. Nondestructive testing (NDT) methods play an increasing role concerning the manufacturing process and the inspection during lifetime. The selection of the best NDT technique for a certain application depends - of course - on many factors including the type, position and size of the defect to be detected but also on secondary issues like accessibility, automation, testing costs, reliability and resolution to mention only some. For the more technical-scientific part of these issues, the determination of the probability of detection (PoD) plays a significant role. Early in the design process questions should be raised concerning the probability with which certain attribute of interest (a defect that has an effect on the structural behavior) can be detected (and localized) in a certain construction. Several defect types have been identified to be critical like impact damages, undulations and porosity. Test samples out of differently processed Carbon Fiber-Reinforced Polymers (CFRP) as used in the automotive or aeronautical industry have been produced including defects of different type and size. In order to determine the PoD and to check whether a technique is applicable the different partners applied a broad variety of selected NDT techniques including Micro CT, Ultrasound (including phased-array and air-coupled UT), Active Thermography, Eddy Current, Vibration and Visual Analysis and Local Acoustic Resonance Spectroscopy (LARS). The presentation will summarize some of the results of the experiments and ongoing data analysis.

  8. Comparison of NDT techniques to evaluate CFRP. Results obtained in a MAIzfp round robin test

    International Nuclear Information System (INIS)

    Grosse, Christian U.

    2016-01-01

    Fiber reinforced polymeric materials are used for lightweight constructions and are an integral part of cars, airplanes or rotor blades of wind turbines. Nondestructive testing (NDT) methods play an increasing role concerning the manufacturing process and the inspection during lifetime. The selection of the best NDT technique for a certain application depends - of course - on many factors including the type, position and size of the defect to be detected but also on secondary issues like accessibility, automation, testing costs, reliability and resolution to mention only some. For the more technical-scientific part of these issues, the determination of the probability of detection (PoD) plays a significant role. Early in the design process questions should be raised concerning the probability with which certain attribute of interest (a defect that has an effect on the structural behavior) can be detected (and localized) in a certain construction. Several defect types have been identified to be critical like impact damages, undulations and porosity. Test samples out of differently processed Carbon Fiber-Reinforced Polymers (CFRP) as used in the automotive or aeronautical industry have been produced including defects of different type and size. In order to determine the PoD and to check whether a technique is applicable the different partners applied a broad variety of selected NDT techniques including Micro CT, Ultrasound (including phased-array and air-coupled UT), Active Thermography, Eddy Current, Vibration and Visual Analysis and Local Acoustic Resonance Spectroscopy (LARS). The presentation will summarize some of the results of the experiments and ongoing data analysis.

  9. The main tasks and obtained results within soil protection working group of the Danube countries

    International Nuclear Information System (INIS)

    Dzatko, M.

    1997-01-01

    In the frame of the Danube Countries Working Community activities was in 1993 constituted independent Soil Protection Working Group (SPWG). Its primary task is to elaborate principles and common soil protection concept in given countries accepted on the level of governments and related authorities, and also to the solution of the solution of the problems on regional levels. Final objective is to implement such concept of soil protection policy, which is able to maintain its quality and productivity potential for next generations also. Based on four years activities coordination could be significance and the SPWG relevance expressed in following topics: (1) Soil pollution and soil degradation, particularly in most pos-communistic countries has been attaining high degree, and in many locations also the threshold of ecological be arability. As reclamation and revitalization of the degraded and polluted soils require long time and considerable financial means, it is not only moral;, even also economically more effective to protect preventively than subsequent reclamation. (2) Main objective of the correct soil protection policy should be its high quality conservation also for the next generations. To this is joined also the protection not only productional, but also non-productional functions, particularly filtrational, transformational and buffering capacibility, including its role and significance, as land and environment. From, in this way considered relationships reality is resulting that the soil protection objectives are not only laws and prohibition approvement, but also active relationships harmonization between the man requirements and soil productivity potential, in order of the sustainable land resources use for the next generations. (3) Based on mentioned realities and relationships we consider the SPWG as an active gremium for elaboration of the the uniform soil protection concepts for governments and responsible organisations that in financial consequence

  10. Implantation of peritoneal catheters by laparotomy: nephrologists obtained similar results to general surgeons

    Directory of Open Access Journals (Sweden)

    Restrepo CA

    2014-10-01

    Full Text Available Cesar A Restrepo, Carlos Alberto Buitrago, Cielo Holguin Division of Nephrology, Department of Health Sciences, Caldas University, Caldas, ColombiaPurpose: To analyze the complications and costs of minilaparotomies performed by a nephrologist (group A compared with conventional laparotomies performed by a surgeon (group B for peritoneal catheter implantation.Setting: Two university hospitals (Santa Sofia and Caldas in Manizales, Caldas, Colombia.Methods: The study included stage 5 chronic kidney disease patients, with indication of renal replacement therapy, who were candidates for peritoneal dialysis and gave informed consent for a peritoneal catheter implant. Minilaparotomies were performed by a nephrologist in a minor surgery room under local anesthesia. Conventional laparotomies were performed by a surgeon in an operating room under general anesthesia.Results: Two nephrologists inserted 157 peritoneal catheters, and seven general surgeons inserted 185 peritoneal catheters. The groups had similar characteristics: the mean age was 55 years, 49.5% were men, and the primary diagnoses were diabetic nephropathy, hypertensive nephropathy, and unknown etiology. The implant was successful for 98.09% of group A and 99.46% of group B. There was no procedure-related mortality. The most frequent complications in the first 30 days postsurgery in group A versus group B, respectively, were: peritonitis (6.37% versus 3.78%, exit-site infection (3.82% versus 2.16%, tunnel infection (0% versus 0.54%, catheter entrapment by omentum (1.27% versus 3.24%, peritoneal effluent spillover (1.91% versus 2.16%, draining failure (4.46% versus 6.49%, hematoma (0% versus 1.08%, catheter migration with kinking (3.18% versus 2.70%, hemoperitoneum (1.27% versus 0%, and hollow viscera accidental puncture (1.91% versus 0.54%. There were no statistically significant differences in the number of complications between groups. In 2013, the cost of a surgeon-implanted peritoneal

  11. Study liquid length penetration results obtained with a direct acting piezo electric injector

    International Nuclear Information System (INIS)

    Payri, Raul; Gimeno, Jaime; Bardi, Michele; Plazas, Alejandro H.

    2013-01-01

    Highlights: ► A direct acting injector capable of controlling needle lift has been used to determine liquid phase penetration. ► The influence of injection pressure, chamber density and chamber temperature have been measured. ► When needle lift is reduced the stabilized liquid length is shortened. ► The relationship between needle lift and liquid length makes needle lift as a new way to control the injection event. - Abstract: A state of the art prototype common rail injector featuring direct control of the needle by means of a piezo stack (direct acting) has been tested. Liquid phase penetration of the sprays in diesel engine-like conditions has been studied via imaging technique in a novel continuous flow test chamber that allows an accurate control on a wide range of thermodynamic conditions (up to 1000 K and 15 MPa). This state of the art injector fitted with a 7-hole nozzle, allows a fully flexible control on the nozzle needle movement, enabling various fuel injection rate typologies. The temporal evolution of the seven sprays has been studied recording movies of the injection event in evaporative conditions via Mie scattering imaging technique and using a high speed camera. The results showed a strong influence of needle position on the stabilized liquid length while the effect of the injection pressure is negligible: the decrease of the needle lift causes a pressure drop in the needle seat and thus a reduction in the effective pressure upstream of the orifices (in the nozzle sac). According to known literature the stabilized liquid-length depends mainly on effective diameter, spray cone-angle and fuel/air properties and does not depend on fuel velocity at the orifice outlet. Therefore, due to small change in the spray cone-angle, higher injection pressures give slightly lower liquid length. However, partial needle lifts has an opposite effect: when needle is partially lifted a dramatic increase of the spray cone-angle and a consequent reduction of

  12. Major results of the electron cyclotron heating experiment in the PDX tokamak

    International Nuclear Information System (INIS)

    Hsuan, H.; Bol, K.; Bowen, N.

    1984-07-01

    Electron Cyclotron Heating (ECH) experiments on PDX have been carried out with two 60 GHz pulsed gyrotrons each yielding up to approximately 100 kW. The ECH system used two waveguide runs each about 30 meters long. One run included 5 bends and the other, 7 bends. Predetermined waveguide modes were transmitted. The electron cyclotron waves were launched in narrow beams from both the high field and the low field sides of the plasma torus. The major new physics results are: (1) efficient central electron heating for both ohmic and neutral beam heated target plasmas; (2) alteration of MHD behavior using ECH; (3) identification of the trapped electron population with ECH; and (4) signature of velocity-space time evolution during ECH. In the best heating results obtained, Thomson scattering data indicated a central temperature increase from less than or equal to 1.5 keV to greater than or equal to 2.5 keV. This occurred with an average density of about 10 13 cm -3 and approximately 80 kW outside-launch ordinary-mode heating

  13. Results from CrIS-ATMS Obtained Using the AIRS Science Team Retrieval Methodology

    Science.gov (United States)

    Susskind, Joel; Kouvaris, Louis C.; Iredell, Lena

    2013-01-01

    which significantly improved results of AIRS Version-6. Version-5.70 CrIS/ATMS temperature profile and surface skin temperature retrievals are of very good quality, and are better than AIRS Version-5 retrievals, but are still significantly poorer than those of AIRS Version-6. CrIS/ATMS retrievals should improve when a Neural-Net start-up system is ready for use. We also examined CrIS/ATMS retrievals generated by NOAA using their NUCAPS retrieval algorithm, which is based on earlier versions of the AIRS Science Team retrieval algorithms. We show that the NUCAPS algorithm as currently configured is not well suited for climate monitoring purposes.

  14. Methodology to obtain exchange properties of the calcite surface-Application to major and trace elements: Ca(II), HCO3-, and Zn(II)

    International Nuclear Information System (INIS)

    Tertre, E.; Beaucaire, C.; Juery, A.; Ly, J.; Tertre, E.; Beaucaire, C.; Juery, A.; Ly, J.

    2010-01-01

    Sorption of inorganic elements onto carbonate minerals has been intensively described in the literature by two reaction steps: (1) a first one rapid and completed within a few hours and (2) a second one slower, eventually irreversible, and occurring at a constant rate. The first step is often attributed to an ion-exchange process, but its reversibility is rarely investigated. Consequently, discrimination of the global sorption phenomenon into two different mechanisms is not always justified. In this study, we investigated, by batch experiments, both sorption and desorption of Ca(II), HCO 3 - , and Zn(II), radiolabeled with isotopes 45 Ca(II), H 14 CO 3 - , and 65 Zn(II), respectively, onto synthetic pure calcite. Solutions were pre-equilibrated with atmospheric p(CO 2 ) and saturated with respect to calcite. Therefore, our purpose was to: (1) obtain experimental distribution coefficients of major elements (Ca(II) and HCO 3 - ) and a trace element (Zn(II)) onto calcite from sorption and desorption experiments, (2) test the validity of a first-occurring ion-exchange process generally noted in the literature, by calculating distribution coefficients for the 'sole' exchange process, and (3) quantify the amounts of Ca(II), HCO 3 - , and Zn(II) sorbed on the calcite surface by the sole 'exchange process' and compare them with surface crystallochemical data. Ca(II) or HCO 3 - sorption experimental data suggest that a significant fraction of these two elements was sorbed irreversibly onto or in the calcite. By using a method based on isotopic ratios, the Ca(II) or HCO 3 - concentrations, which are reversibly adsorbed on the calcite, have been quantified. These concentrations are respectively estimated at 4. 0 ± 2. 0 * 10 -4 and 7. 0 ± 1. 5 * 10 -4 mol/kg. The obtained Ca(II) surface concentration value is one order of magnitude lower than the one obtained from isotopic measurement by former authors [Geochim. Cosmochim. Acta 55 (1991) 1549; Geochim. Cosmochim. Acta 51

  15. An Objective Screening Method for Major Depressive Disorder Using Logistic Regression Analysis of Heart Rate Variability Data Obtained in a Mental Task Paradigm

    Directory of Open Access Journals (Sweden)

    Guanghao Sun

    2016-11-01

    Full Text Available Background and Objectives: Heart rate variability (HRV has been intensively studied as a promising biological marker of major depressive disorder (MDD. Our previous study confirmed that autonomic activity and reactivity in depression revealed by HRV during rest and mental task (MT conditions can be used as diagnostic measures and in clinical evaluation. In this study, logistic regression analysis (LRA was utilized for the classification and prediction of MDD based on HRV data obtained in an MT paradigm.Methods: Power spectral analysis of HRV on R-R intervals before, during, and after an MT (random number generation was performed in 44 drug-naïve patients with MDD and 47 healthy control subjects at Department of Psychiatry in Shizuoka Saiseikai General Hospital. Logit scores of LRA determined by HRV indices and heart rates discriminated patients with MDD from healthy subjects. The high frequency (HF component of HRV and the ratio of the low frequency (LF component to the HF component (LF/HF correspond to parasympathetic and sympathovagal balance, respectively.Results: The LRA achieved a sensitivity and specificity of 80.0% and 79.0%, respectively, at an optimum cutoff logit score (0.28. Misclassifications occurred only when the logit score was close to the cutoff score. Logit scores also correlated significantly with subjective self-rating depression scale scores (p < 0.05.Conclusion: HRV indices recorded during a mental task may be an objective tool for screening patients with MDD in psychiatric practice. The proposed method appears promising for not only objective and rapid MDD screening, but also evaluation of its severity.

  16. Cognitive Learning Strategy as a Partial Effect on Major Field Test in Business Results

    Science.gov (United States)

    Strang, Kenneth David

    2014-01-01

    An experiment was developed to determine if cognitive learning strategies improved standardized university business exam results. Previous studies revealed that factors such as prior ability, age, gender, and culture predicted a student's Major Field Test in Business (MFTB) score better than course content. The experiment control consisted of…

  17. Residual life assessment of major LWR components: NPAR approach and results

    International Nuclear Information System (INIS)

    Shah, V.N.; Weidenhamer, G.H.; Vora, J.P.

    1991-01-01

    The nuclear plant aging research (NPAR) program is systematically addressing the technical issues associated with understanding and managing aging of major LWR components. Twenty-one major components have been identified and prioritized according to their relevance to plant safety. Qualitative aging assessment has identified pertinent design features, materials, stressors, environments, aging mechanisms. and failure modes for each of the components. Emerging inspection, surveillance, and monitoring methods to characterize aging damage and mitigation methods to reduce the damage are currently being assessed. The results of all these assessments are used to develop life-assessment procedures for the components and are included in appropriate documents supporting the regulatory requirements for license renewal. (author)

  18. Pipeline inspection - failures selection and results obtained; Inspeccion interna de ductos - seleccion de fallas y resultados obtenidos

    Energy Technology Data Exchange (ETDEWEB)

    Motylicki, Juan Enrique [Oleoductos del Valle S.A. (OLDEVAL S.A.), (Argentina)

    2003-07-01

    The main objective of the pipelines maintenance is to assure the integrity of them in order to have a reliable operation and with an acceptable level of risk that minimizes the impact to people, to the environment and the business. The objective of this work is to expose the experiences obtained before by Oldelval and after the passages of the intelligent pig, carried out in the years 1999/2000. In the same one they will be described: How the flaws were selected to verify / to repair. Results obtained in digs. Laboratory studies to determine like they affect to the integrity of the pipeline, the different types of opposing plane defects. Conclusions. (author)

  19. Competency test result of vocational school teacher's majoring light vehicles subject in East Jakarta

    Science.gov (United States)

    Dudung, Agus

    2018-03-01

    The purpose of this study of Teacher Competency Test (UKG) is to know about (a) the description of the vocational school teachers' competency test result majoring light vehicle subject in eastern Jakarta, (b) the effect between those certified teachers, non-certified teachers, civil servant teachers and non-civil servant teachers to Teacher Competency Test (UKG) result. The UKG result indicates that (1) certified teachers hold the highest score, however non-certified teachers obtain at the average of 55, in terms of UKG technicality preparation; (2) there are 43 teachers (48.9%) mention that the room facility for conducting UKG is good, while 45 teachers (51.1%) mention the opposite opinion. This shows that the average UKG room is relatively good enough. Meanwhile, in terms of youth facilities availability, (3) there are 86 teachers (97.7%) agree that the facilities are good while 2 teachers (2.3%) say the opposite opinion. This shows that the average UKG preparation is relatively very good. About the implementation of UKG, (4) there are 65 teachers (73,9%) give good impression, while 23 teachers (26,1%) give poor quality impression. This shows that the average UKG implementation is relatively good. About the way UKG is managed, (5) there are 87 teachers (98,9%) identify satisfactory comments, while there is only 1 teacher (1,1%) gives unsatisfactory comment. This shows that the average UKG management is relatively very good. ANNOVA analysis is used in this study to estimate the effect of UKG on certified and non-certified teachers. The ANNOVA test result shows that (6) H_0 is accepted because α = 0,05 facilities such as (a) test Room, (b) UKG readiness, (c) UKG implementation (d) UKG management including UKG materials. (2) The grid in the given test should (a) represent the content of the syllabus/curriculum or materials that teachers teach appropriately and proportionately (b) represent the components which are clearly and easily understood by the teachers as

  20. Evaluation of major polluting accidents in China-Results and perspectives

    International Nuclear Information System (INIS)

    Hou Yu; Zhang Tianzhu

    2009-01-01

    Lessons learnt from accidents are essential sources for updating state-of-the-art requirements in pollution accident prevention. To improve this input in the People's Republic of China in a systematic way, a database for collecting and evaluating major pollution accidents is being established. This is being done in co-operation with Chinese Society for Environment Sciences and other national Institutions. At the time of writing over 80 major events from 2002-2006 have been collected. In this paper, a summary evaluation on the major polluting events in China from 2002 to 2006 is presented and some basic lessons drawn shown. There is no a systematic pollution accident notification system currently in China. The results from root cause analysis underline the importance of emergency measures, maintenance, human factor issues and the role of safety organization. Chronic pollution, especially water pollution and air pollution should be paid the same attention as the sudden pollution. It is important to keep in mind that collecting information from major accidents represents a small percentage of the actual number of events taking place.

  1. Overview of results and perspectives from the Shoreham major common-cause initiating events study

    International Nuclear Information System (INIS)

    Joksimovich, V.; Orvis, D.D.; Paccione, R.J.

    1986-01-01

    This study represents the continuation of a large effort by LILCO to fully understand the potential hazards posed by future operation of the Shoreham Nuclear Power Stations (SNPS). The Shoreham Probabilistic Risk Assessment, a level 3 PRA without external events, provided a characterization of the accident sequences that could leave the core in a condition in which it would be vulnerable to severe damage if further mitigating actions were not taken. It estimated the frequency and magnitude of the potential radioactivity releases associated with such sequences. The study was limited to accident sequences initiated by so called internal events to the plant including a loss of offsite power. It also characterized the public risk associated with those accident sequences. The ''Major Common-Cause Initiating Events Study'' (MCCI) for the Shoreham plant was performed to obtain insights into the plant's susceptibility to, and inherent defenses against, certain MCCIs. Major common-cause initiating events are occurrences which have the potential to initiate a plant transient or LOCA and, also, damage one or more plant systems needed to mitigate the effects of a transient or LOCA. The scope of the MCCI study included detailed analyses of seismic events and fires through the severe core damage and bounding analyses of aircraft crashes, windstorms, turbine missiles and release of hazardous materials near the plant

  2. New high-definition thickness data obtained at tropical glaciers: preliminary results from Antisana volcano (Ecuador) using GPR prospection

    Science.gov (United States)

    Zapata, Camilo; Andrade, Daniel; Córdova, Jorge; Maisincho, Luis; Carvajal, Juan; Calispa, Marlon; Villacís, Marcos

    2014-05-01

    The study of tropical glaciers has been a significant contribution to the understanding of glacier dynamics and climate change. Much of the data and results have been obtained by analyzing plan-view images obtained by air- and space-borne sensors, as well as depth data obtained by diverse methodologies at selected points on the glacier surface. However, the measurement of glacier thicknesses has remained an elusive task in tropical glaciers, often located in rough terrains where the application of geophysical surveys (i.e. seismic surveys) requires logistics sometimes hardly justified by the amount of obtained data. In the case of Ecuador, however, where most glaciers have developed on active volcanoes and represent sources/reservoirs of fresh water, the precise knowledge of such information is fundamental for scientific research but also in order to better assess key aspects for the society. The relatively recent but fast development of the GPR technology has helped to obtain new highdefinition thickness data at Antisana volcano that will be used to: 1) better understand the dynamics and fate of tropical glaciers; 2) better estimate the amount of fresh water stored in the glaciers; 3) better assess the hazards associated with the sudden widespread melting of glaciers during volcanic eruptions. The measurements have been obtained at glaciers 12 and 15 of Antisana volcano, with the help of a commercial GPR equipped with a 25 MHz antenna. A total of 30 transects have been obtained, covering a distance of more than 3 km, from the glacier ablation zone, located at ~ 4600 masl, up to the level of 5200 masl. The preliminary results show a positive correlation between altitude and glacier thickness, with maximum and minimum calculated values reaching up to 80 m, and down to 15 m, respectively. The experience gained at Antisana volcano will be used to prepare a more widespread GPR survey in the glaciers of Cotopaxi volcano, whose implications in terms of volcanic hazards

  3. Pregnancy does not affect HIV incidence test results obtained using the BED capture enzyme immunoassay or an antibody avidity assay.

    Directory of Open Access Journals (Sweden)

    Oliver Laeyendecker

    2010-10-01

    Full Text Available Accurate incidence estimates are needed for surveillance of the HIV epidemic. HIV surveillance occurs at maternal-child health clinics, but it is not known if pregnancy affects HIV incidence testing.We used the BED capture immunoassay (BED and an antibody avidity assay to test longitudinal samples from 51 HIV-infected Ugandan women infected with subtype A, C, D and intersubtype recombinant HIV who were enrolled in the HIVNET 012 trial (37 baseline samples collected near the time of delivery and 135 follow-up samples collected 3, 4 or 5 years later. Nineteen of 51 women were also pregnant at the time of one or more of the follow-up visits. The BED assay was performed according to the manufacturer's instructions. The avidity assay was performed using a Genetic Systems HIV-1/HIV-2 + O EIA using 0.1M diethylamine as the chaotropic agent.During the HIVNET 012 follow-up study, there was no difference in normalized optical density values (OD-n obtained with the BED assay or in the avidity test results (% when women were pregnant (n = 20 results compared to those obtained when women were not pregnant (n = 115; for BED: p = 0.9, generalized estimating equations model; for avidity: p = 0.7, Wilcoxon rank sum. In addition, BED and avidity results were almost exactly the same in longitudinal samples from the 18 women who were pregnant at only one study visit during the follow-up study (p = 0.6, paired t-test.These results from 51 Ugandan women suggest that any changes in the antibody response to HIV infection that occur during pregnancy are not sufficient to alter results obtained with the BED and avidity assays. Confirmation with larger studies and with other HIV subtypes is needed.

  4. Method of forecasting pollutant transfer in an aquifer initial results obtained in a sandy medium (Barp site, Gironde)

    International Nuclear Information System (INIS)

    Madoz-Escande, C.; Peyrus, J.-C.

    1979-01-01

    Hydrogeological studies are undertaken in the context of the radiological safety of nuclear plants to forecast consequences of accidental releases of radioactive pollutants into an aquifer (transfer time, concentration at points of emergence). This quantitative forecast is obtained with the aid of a mathematical model with sequential emission. This requires a knowledge of the physical parameters of the aquifer and of the behavior of the pollutant in relation to the water-bearing medium. The physical parameters of a saturated porous medium are presented with the aid of radioactive tracer tests on a model and also in the field. The initial results obtained in a sandy medium are presented. In view of the difficulty of extrapolating to field conditions the conclusions of tests on models, it was necessary to set up a mobile laboratory with which in situ studies could be undertaken. The behavior of the pollutant in relation to the water-bearing medium is the subject of preliminary laboratory research on the laws of adsorption under different pH and temperature conditions. The numerical results obtained call for confirmation in the field. A description is given of a method which should enable the distribution coefficients to be evaluated in situ

  5. Assessment of the French environment radiological status in 2009. Synthesis of the results obtained by the IRSN survey networks

    International Nuclear Information System (INIS)

    2009-01-01

    After a brief recall of the IRSN's missions, this report describes why and how radioactivity is controlled in France. It presents the national network for environment radioactivity measurements, and indicates the objectives of this radiological survey. It comments the status and levels of the natural and artificial radioactivity in France, discusses the results of the territory general survey (atmosphere, inland, coast, regions), the results of fuel cycle related sites (nuclear sites, old mining sites, front end industries, electricity production plants, back end industries, waste storage sites), the results concerning the nuclear medicine radioactive releases, the results obtained during selective expertises, and discusses the assessment of the exposure of the French population to ionizing radiations. It finally indicates how those data are published

  6. New dynamics information from experimental results obtained in d-Au collisions at RHIC-BNL energies

    International Nuclear Information System (INIS)

    Jipa, Alexandru

    2004-01-01

    During the last runs d-Au collisions at √s NN = 200 GeV have been investigated at RHIC-BNL using the BRAHMS Experiment. Some interesting experimental results on charged particle multiplicities, rapidity distributions, transverse momentum spectra, antiparticle to particle ratios, participant spectator evolution have been obtained. In this work the most interesting results are presented for different rapidity and collision centrality ranges. Taking into account the importance of the collision geometry and collision symmetry in the collision dynamics, comparisons with the similar experimental results obtained in Au-Au collisions have been done. New interesting results can be reported. The most significant are related to the evolution of the nuclear modification factor with rapidity and collision centrality. The high transverse momentum suppression and the behaviours in different rapidity and centrality ranges suggest strong initial state effects. These effects could be related to the gluonic structure of the colliding nuclei. Some insights on the Color Glass Condensate formation are possible. (author)

  7. [The medical dissertation--no definitive model. Results of a survey about obtaining a doctorate contradict frequently stated opinions].

    Science.gov (United States)

    Weihrauch, M; Strate, J; Pabst, R

    2003-12-05

    The relevance of medical dissertations is controversial in Germany. The "Wissenschaftsrat" (Science Council) of Germany even made the radical proposal of abolishing medical dissertations, in their present form, in the recently published "Guidelines on writing a thesis". Using a questionnaire with 22 items all students submitting their dissertations within one year at the Medical School in Hannover were asked to participate in a survey about the dissertation, supervision, time spent on it and publishing the results. The answers were evaluated statistically by explorative data analysis. A total of 232 questionnaires were evaluated, which is equivalent to a response rate of 87% (47% were women). A majority of 69% had prepared their thesis in a clinical institution. The supervision during various phases of the dissertation was graded as good. Altogether 90% thought that it had been personally worth-while. In 57% of cases the data of the dissertation had already been published and in 39 % of these cases the author of the dissertation was listed as first author of the publication. In agreement with former studies in German universities an overwhelming majority of 90% of respondents graded dissertations as a significant part of their medical studies, although requiring much additional time. They would recommend such a research phase to younger students as highly valuable. These results are in contrast to many repeatedly made statements.

  8. Matching the results of a theoretical model with failure rates obtained from a population of non-nuclear pressure vessels

    International Nuclear Information System (INIS)

    Harrop, L.P.

    1982-02-01

    Failure rates for non-nuclear pressure vessel populations are often regarded as showing a decrease with time. Empirical evidence can be cited which supports this view. On the other hand theoretical predictions of PWR type reactor pressure vessel failure rates have shown an increasing failure rate with time. It is shown that these two situations are not necessarily incompatible. If adjustments are made to the input data of the theoretical model to treat a non-nuclear pressure vessel population, the model can produce a failure rate which decreases with time. These adjustments are explained and the results obtained are shown. (author)

  9. Aero thermal test results obtained on the n. C 5 EL 4 Cluster in the atmospheric pressure cell

    International Nuclear Information System (INIS)

    Gasc, B.

    1964-01-01

    In the framework of thermal studies on the EL-4 cluster, the full-scale tests at atmospheric pressure are designed to permit measurement of local values of the wall temperature, of the velocity and of the temperature in the fluid. The experimental results, obtained with the help of an original measuring apparatus, make it possible to follow the changes in these values along the cluster and to predict in much detail the in-pile thermal behaviour. In particular it is shown that changes in the wall temperature along the cluster are greatly influenced by disruption of the flow caused by grids and supports. (author) [fr

  10. Comparison between dosimeter films and electronic dosimeters results obtained in F-18 production practices at IEN/CNEN

    International Nuclear Information System (INIS)

    Paulo, Osvaldir; Carlos, Luiz R.J.; Mendes, Milton

    2008-01-01

    Full text: The aim of the present work is the comparison of the dose rates values obtained from dosimeter films with the values obtained from electronic dosimeters used by radiological protection technician involved in practices with fluorine-18 production in CV-28 cyclotron at IEN/CNEN. The motivation for this work was the increase on the demand of this radiopharmaceutical. Nowadays there is an increase demand on the number of clinics and hospitals which had started to use the technique of radiodiagnostic using positron-emission tomography (PET). Therefore, the produced radionuclide activities (physics quantity) and also the complexity of the practices of radiological protection in the areas of that facility had increased a lot. The conventional statistical methods will be used to evaluate the results obtained in the analysis of the data obtained in the reading of the dosimeters. This comparative method is however a first step to taking decisions regarding radiological protection service. Therefore that the radiometric surveys of routine are taken in consideration, as well as the information from the technician of radiological protection that is working in those areas. All this data will give support to improve and implement methods and practices on the accelerators' facilities. In addition, the use of these electronic dosimeters will makes possible the technician read these dose rates received immediately during the practices and use these information you make decisions. In case of dose rates values to present above the expected the practice will be ploughed. Another point to be considered is that this work will propitiate the future updates of the procedures designated to those practices and to conduct at the radiological protection optimization. (author)

  11. The Normal Position of Umbilicus in the Newborn: An Aid to Improve Cosmetic Result in Exomphalos Major

    Directory of Open Access Journals (Sweden)

    H Davari

    2004-02-01

    Full Text Available Background: Position of umbilicus is an important esthetic landmark and its absence or deformity may be associated with poor self-image. In abdominoplasty, the creation of a normal-looking, well shaped and sufficiently deep umbilicus on a normal position seems essential. The aim of this study was to determine the normal position of umbilicus and hence to improve the cosmetic result of exomphalos major repair. Methods: In a cross-sectional study the position of umbilicus was determined in a random sample of 200 healthy and normal neonates (107 boys and 93 girls who were born in Isfahan University hospitals from Oct. 2002 till Mar. 2003, with respect to the xiphisternum and pubis. Results: The normal umbilical position was 59.3 ± 5.2 percent of the way from the inferior border of xiphisternum to the superior border of the pubis in the midline and it was independent of gender and neonatal Conclusions: Recent years have witnessed major improvements in the survival of newborns with exomphalocele. The primary repair of the abdominal wall with umbilicoplasty is generally considered the treatment of choice, and the cosmetic appearance of the navel becomes increasingly important as children grow older. In repair of exomphalos major, the most esthetically pleasing result is obtained if the umbilicus is placed 59.3% of the way from the xiphisternum to the pubis. Keywords: Umbilicus, Exomphalos, Neonate, Umbilicoplasty, Isfahan

  12. [Results of hematopoietic stem cell transplantation in hemoglobinopathies: thalassemia major and sickle cell disease].

    Science.gov (United States)

    Hladun, R; Elorza, I; Olivé, T; Dapena, J L; Llort, A; Sánchez de Toledo, J; Díaz de Heredia, C

    2013-08-01

    The prevalence of hemoglobinopathies in Spain is increasing as a result of immigration. Thalassemia major presents with chronic hemolytic anemia that requires regular red blood cell transfusions within the first year of life. Patients with sickle cell disease suffer from chronic anemia, vasculopathy and progressive damage in almost any organ. There is decreased life expectancy in both conditions. Allogeneic hematopoietic stem cell transplantation represents the only potentially curative option. Seventeen patients (fourteen thalassemia major, and three sickle cell disease) underwent allogeneic hematopoietic stem cell transplantations. In the thalassemia group, nine donors were HLA-geno-identical siblings, two were partially matched related donors (one HLA allele mismatch), and three unrelated donors. All three patients with sickle cell disease were transplanted from HLA-geno-identical siblings. The source of stem cells was bone marrow in sixteen cases. Median patient age at transplant was six years (range: 1-16) in the thalassemia group, and twelve years (range: 8-15) in the sickle cell disease group. The graft was successful in all patients. Secondary graft rejection was observed in two thalassemia patients rendering them dependent on blood transfusions. Complete chimerism was observed in thirteen patients and, although mixed chimerism occurred in two, with all of them showing normal hemoglobin levels after transplantation and not requiring further transfusion support. Patients affected by sickle cell disease did not present with new vaso-occlusive crises, and stabilization of pulmonary and neurological function was observed. Chronic graft-versus-host disease was detected in three patients affected by thalassemia, and hypogonadotrophic hypogonadism in five patients. We conclude that for thalassemia major and sickle cell disease, allogenic hematopoietic stem cell transplantation from HLA-geno-identical siblings offers a high probability of complication-free survival

  13. Major results of gravity and magnetic studies at Yucca Mountain, Nevada

    International Nuclear Information System (INIS)

    Oliver, H.W.; Ponce, D.A.; Sikora, R.F.

    1991-01-01

    About 4000 gravity stations have been obtained at Yucca Mountain and vicinity since the beginning of radioactive-waste studies there in 1978. These data have been integrated with data from about 29,000 stations previously obtained in the surrounding region to produce a series of Bouguer and isostatic-residual-gravity maps of the Nevada Test Site and southeastern Nevada. Yucca Mountain is characterized by a WNW-dipping gravity gradient whereby residual values of -10 mGal along the east edge of Yucca Mountain decrease to about -38 mGal over Crater Flat. Using these gravity data, two-dimensional modeling predicted the depth to pre-Cenozoic rocks near the proposed repository to be about 1220 ± 150 m, an estimate that was subsequently confirmed by drilling to be 1244 m. Three-dimensional modeling of the gravity low over Crater Flat indicates the thickness of Cenozoic volcanic rocks and alluvial cover to be about 3000 m. Considerable aeromagnetic coverage of southwestern Nevada was obtained in 1978--1979 to help characterize Yucca Mountain and vicinity. One significant result is the discovery of a series of circular magnetic anomalies in Crater Flat and the northern Amargosa Desert that suggest the presence of buried volcanic centers there. Elongate magnetic highs and associated lows over Yucca Mountain correlate with mapped faults, some of which are only partially exposed. Thus, the data provide inforamtion on the extent and continuity of these faults. 31 refs., 3 figs

  14. Potential theory for stationary Schrödinger operators: a survey of results obtained with non-probabilistic methods

    Directory of Open Access Journals (Sweden)

    Marco Bramanti

    1992-05-01

    Full Text Available In this paper we deal with a uniformly elliptic operator of the kind: Lu  Au + Vu, where the principal part A is in divergence form, and V is a function assumed in a “Kato class”. This operator has been studied in different contexts, especially using probabilistic techniques. The aim of the present work is to give a unified and simplified presentation of the results obtained with non probabilistic methods for the operator L on a bounded Lipschitz domain. These results regard: continuity of the solutions of Lu=0; Harnack inequality; estimates on the Green's function and L-harmonic measure; boundary behavior of positive solutions of Lu=0, in particular a “Fatou's theorem”.

  15. Analysis of results obtained with different cutting techniques and associated filtration systems for the dismantling of radioactive metallic components

    International Nuclear Information System (INIS)

    Bach, F.W.; Steiner, H.; Schreck, G.

    1993-01-01

    The present joint study performed by the Commissariat a l'energie atomique and the Universitaet Hannover and coordinated by the Commission of the European Communities was intended to analyse the results generated in a number of research contracts concerned with cutting tests in air and underwater, with consideration of the prevailing working conditions. The analysis has led to a large database, giving broadly-assessed information for the dismantling of radioactive components. The range of study was enlarged, where possible, to include recently obtained results outside the present research programme, consideration also being given to supplementary cutting tools and filtration systems not covered by the present programme. Data was concentrated in structured information packages on practical experience available for a series of cutting tools and filters. These were introduced into a computerized user-friendly databank, to be considered as a first-stage development, which should be continuously updated and possibly oriented in the future to an expert system

  16. Determination of averaged axisymmetric flow surfaces according to results obtained by numerical simulation of flow in turbomachinery

    Directory of Open Access Journals (Sweden)

    Bogdanović-Jovanović Jasmina B.

    2012-01-01

    Full Text Available In the increasing need for energy saving worldwide, the designing process of turbomachinery, as an essential part of thermal and hydroenergy systems, goes in the direction of enlarging efficiency. Therefore, the optimization of turbomachinery designing strongly affects the energy efficiency of the entire system. In the designing process of turbomachinery blade profiling, the model of axisymmetric fluid flows is commonly used in technical practice, even though this model suits only the profile cascades with infinite number of infinitely thin blades. The actual flow in turbomachinery profile cascades is not axisymmetric, and it can be fictively derived into the axisymmetric flow by averaging flow parameters in the blade passages according to the circular coordinate. Using numerical simulations of flow in turbomachinery runners, its operating parameters can be preliminarily determined. Furthermore, using the numerically obtained flow parameters in the blade passages, averaged axisymmetric flow surfaces in blade profile cascades can also be determined. The method of determination of averaged flow parameters and averaged meridian streamlines is presented in this paper, using the integral continuity equation for averaged flow parameters. With thus obtained results, every designer can be able to compare the obtained averaged flow surfaces with axisymmetric flow surfaces, as well as the specific work of elementary stages, which are used in the procedure of blade designing. Numerical simulations of flow in an exemplary axial flow pump, used as a part of the thermal power plant cooling system, were performed using Ansys CFX. [Projekat Ministarstva nauke Republike Srbije, br. TR33040: Revitalization of existing and designing new micro and mini hydropower plants (from 100 kW to 1000 kW in the territory of South and Southeast Serbia

  17. Major results of gravity and magnetic studies at Yucca Mountain, Nevada

    International Nuclear Information System (INIS)

    Oliver, H.W.; Ponce, D.A.; Sikora, R.F.

    1991-01-01

    About 4,000 gravity stations have been obtained at Yucca Mountain and vicinity since the beginning of radioactive-waste studies there in 1978. These data have been integrated with data from about 29,000 stations previously obtained in the surrounding region to produce a series of Bouguer and isostatic-residual-gravity maps of the Nevada Test Site and southeastern Nevada. Yucca Mountain is characterized by a WNW-dipping gravity gradient whereby residual values of -10 mGal along the east edge of Yucca Mountain decrease to about -38 mGal over Crater Flat. Using these gravity data, two-dimensional modeling predicted the depth to pre-Cenozoic rocks near the proposed repository to be about 1,220±150 m, an estimate that was subsequently confirmed by drilling to be 1,244 m. Three-dimensional modeling of the gravity low over Crater Flat indicates the thickness of Cenozoic volcanic rocks and alluvial cover to be about 3,000 m. Gravity interpretations also identified the Silent Canyon caldera before geologic mapping of Pahute Mesa and provided an estimate of the thickness of the volcanic section there of nearly 5 km. Considerable aeromagnetic coverage of southwestern Nevada was obtained in 1978-79 to help characterize Yucca Mountain and vicinity. One significant result is the discovery of a series of circular magnetic anomalies in Crater Flat and the northern Amargosa Desert that suggest the presence of buried volcanic centers there. If this interpretation is confirmed by drilling, the magnetic data can be used to help estimate the total volume of buried volcanic rocks, which, along with radiometric dating, could help provide a better prediction of future volcanism. Elongate magnetic highs and associated lows over Yucca Mountain correlate with mapped faults, some of which are only partially exposed. Thus, the data provide information on the extent and continuity of these faults

  18. Edaphic macrofauna as biological indicator of the conservation/disturbance status of soil. Results obtained in Cuba

    International Nuclear Information System (INIS)

    Cabrera, Grisel

    2012-01-01

    In order to predict the degradation status of a soil, a group of variables comprising its physical, chemical and/or biological properties is used. Macrofauna, which includes soil invertebrates higher than 2 mm of diameter, is a biological component that can be used for such purpose. Its taxonomic richness as well as its density, biomass and functional composition change depending on the effect of diverse land uses and managements. This review reaffirms that the macrofauna characteristics and the results obtained, mainly in Cuba, about its variation in ecosystems with different anthropization levels, support the potential use of this fauna as biological indicator of the soil's conservation status. Future studies should consider a lower taxonomic level in the identification of macrofauna, and relate its taxonomic and functional composition to the climate and pedological factors. (author)

  19. Major Results of SBLOCA Tests with VISTA-ITL for the SMART Design

    International Nuclear Information System (INIS)

    Park, Hyun Sik; Min, Byoung Yeon; Shin, Yong Chul; Choi, Nam Hyun; Chung, Young Jong; Lee, Won Jae; Yi, Sung Jae

    2012-01-01

    A thermal-hydraulic integral effect test facility, VISTAITL, for the SMART design has been constructed by the Korea Atomic Energy Research Institute (KAERI). The VISTA-ITL has the simulation capability of small break loss of coolant accident (SBLOCA), passive residual heat removal system (PRHRS) performance, and complete loss of RCS (Reactor Coolant System) flowrate (CLOF), etc. The VISTA-ITL is a 1/2.77- height and 1/1310-volume scaled test facility based on the design features of SMART. The reference scale ratios of length (1/2.77) and area (1/472.9) are based on the elevation difference between the core and steam generator centers and the core flow area, respectively. According to the scaling law, the reduced height scaling results in time reducing results in the model and the time scale ratio is 1/1.664. Three SBLOCA tests of safety injection system (SIS) line break, shutdown cooling system (SCS) line break and pressurizer safety valve (PSV) line break were successfully performed and its major results have been compared and discussed in this paper

  20. Major results of geophysical investigations at Yucca Mountain and vicinity, southern Nevada

    International Nuclear Information System (INIS)

    Oliver, H.W.; Ponce, D.A.; Hunter, W.C.

    1995-01-01

    In the consideration of Yucca Mountain as a possible site for storing high level nuclear waste, a number of geologic concerns have been suggested for study by the National Academy of Sciences which include: (1) natural geologic and geochemical barriers, (2) possible future fluctuations in the water table that might flood a mined underground repository, (3) tectonic stability, and (4) considerations of shaking such as might be caused by nearby earthquakes or possible volcanic eruptions. This volume represents the third part of an overall plan of geophysical investigation of Yucca Mountain, preceded by the Site Characterization Plan (SCP; dated 1988) and the report referred to as the Geophysical White Paper, Phase 1, entitled Status of Data, Major Results, and Plans for Geophysical Activities, Yucca Mountain Project (Oliver and others, 1990). The SCP necessarily contained uncertainty about applicability and accuracy of methods then untried in the Yucca Mountain volcano-tectonic setting, and the White Paper, Phase 1, focused on summarization of survey coverage, data quality, and applicability of results. For the most part, it did not present data or interpretation. The important distinction of the current volume lies in presentation of data, results, and interpretations of selected geophysical methods used in characterization activities at Yucca Mountain. Chapters are included on the following: gravity investigations; magnetic investigations; regional magnetotelluric investigations; seismic refraction investigations; seismic reflection investigations; teleseismic investigations; regional thermal setting; stress measurements; and integration of methods and conclusions. 8 refs., 60 figs., 2 tabs

  1. First In-Core Measurement Results Obtained with the Innovative Mobile Calorimeter CALMOS inside the OSIRIS Material Testing Reactor

    International Nuclear Information System (INIS)

    Carcreff, Hubert; Salmon, Laurent; Courtaux, Cedric

    2013-06-01

    Nuclear heating rate inside an MTR has to be known in order to design and to run irradiation experiments which have to fulfill target temperature constraints. This measurement is usually carried out by calorimetry [1, 2]. An innovative calorimetric system, CALMOS, has been studied and built in 2011 for the 70 MWth OSIRIS reactor operated by CEA. Thanks to a new calorimetric probe, associated to a specific displacement system, it provides measurements along the fissile height and above the core. The development of the calorimetric probe required the manufacturing and the irradiation of mock-ups in the ex-core area, where nuclear heating rate does not exceed 2 W.g -1 . The calorimeter working mode, the different measurement procedures allowed with such a new probe and main modeling and experimental results have been already presented [3, 4]. In this paper, we present the first results obtained during several measurement campaigns carried out in 2012 and 2013 inside the OSIRIS core with the final device. For the first time, this new experimental measurement system was operated in nominal in-core thermo hydraulic conditions with nominal neutron and gamma fluxes (up to 6 W.g -1 ) in several experimental locations. After a brief presentation of the displacement system specificities, first nuclear heating distributions are presented and discussed. Experimental data were also used to upgrade the Finite Element model of the calorimeter in order to match measured temperatures with calculated ones. This model allowed to estimate a Kc correction factor which takes into account small nonlinearities when the heating rate is deduced from the calibration method. A comparison is made between nuclear heating rates determined from the probe calibration and from the zero method. In addition, an evaluation of the global uncertainty associated to the measurements is detailed. Finally, a global comparison is made with available measurements obtained from previous calorimeters. (authors)

  2. First in-core measurement results obtained with the innovative mobile calorimeter CALMOS inside the OSIRIS material testing reactor

    International Nuclear Information System (INIS)

    Carcreff, Hubert; Salmon, Laurent; Courtaux, Cedric

    2014-01-01

    Nuclear heating rate inside an MTR has to be known in order to design and to run irradiation experiments which have to fulfill target temperature constraints. This measurement is usually carried out by calorimetry. An innovative calorimetric system, CALMOS, has been studied and built in 2011 for the 70 MWth OSIRIS reactor operated by CEA. Thanks to a new calorimetric probe, associated to a specific displacement system, it provides measurements along the fissile height and above the core. Development of the calorimetric probe required manufacturing and irradiation of mock-ups in the ex-core area, where nuclear heating rate does not exceed 2 W.g -1 . The calorimeter working mode, the different measurement procedures, main modeling and ex-core experimental results have been already presented in previous papers. In this paper, we present in-core results obtained from 2011 to 2013 with the final device. For the first time, this new experimental measurement system was operated in several experimental locations, with nominal in-core thermal hydraulic conditions, nominal neutron flux and nuclear heating rate up to 6 W.g -1 (in graphite). After a brief presentation of the displacement system specificities, first nuclear heating distributions are presented and discussed. The Finite Element model of the calorimeter was upgraded in order to match calculated temperatures with measured ones. This 'validated' model allowed to estimate a Kc factor which tends to correct small nonlinearities when heating rate is calculated from the 'calibration method'. A comparison is made between nuclear heating rates determined from 'calibration' and 'zero methods'. In addition, an evaluation of the global uncertainty associated to the measurements is detailed. Finally, a comparison is made with available measurements obtained from previous calorimeters. (authors)

  3. Standardization of a fluconazole bioassay and correlation of results with those obtained by high-pressure liquid chromatography.

    Science.gov (United States)

    Rex, J H; Hanson, L H; Amantea, M A; Stevens, D A; Bennett, J E

    1991-01-01

    An improved bioassay for fluconazole was developed. This assay is sensitive in the clinically relevant range (2 to 40 micrograms/ml) and analyzes plasma, serum, and cerebrospinal fluid specimens; bioassay results correlate with results obtained by high-pressure liquid chromatography (HPLC). Bioassay and HPLC analyses of spiked plasma, serum, and cerebrospinal fluid samples (run as unknowns) gave good agreement with expected values. Analysis of specimens from patients gave equivalent results by both HPLC and bioassay. HPLC had a lower within-run coefficient of variation (less than 2.5% for HPLC versus less than 11% for bioassay) and a lower between-run coefficient of variation (less than 5% versus less than 12% for bioassay) and was more sensitive (lower limit of detection, 0.1 micrograms/ml [versus 2 micrograms/ml for bioassay]). The bioassay is, however, sufficiently accurate and sensitive for clinical specimens, and its relative simplicity, low sample volume requirement, and low equipment cost should make it the technique of choice for analysis of routine clinical specimens. PMID:1854166

  4. Prenatal cytogenetic diagnosis in Spain: analysis and evaluation of the results obtained from amniotic fluid samples during the last decade.

    Science.gov (United States)

    Mademont-Soler, Irene; Morales, Carme; Clusellas, Núria; Soler, Anna; Sánchez, Aurora

    2011-08-01

    Chromosome abnormalities are one of the main causes of congenital defects, and establishing their frequency according to the different clinical indications for invasive procedure during pregnancy is especially important for genetic counselling. We analyzed the results of 29,883 amniotic fluid samples referred to our laboratory for cytogenetic studies from 1998 to 2009, which constitutes the largest series of cytogenetic analysis performed on amniotic fluid samples in Spain. The number of samples received tended to increase from 1998 to 2005, but after 2005 it decreased substantially. Cytogenetic results were obtained in 99.5% of the samples, and the detected incidence of chromosome abnormalities was 2.9%. Of these, 48.1% consisted of classical autosomal aneuploidies, trisomy 21 being the most frequent one. The main clinical indications for amniocentesis were positive prenatal screening and advanced maternal age, but referral reasons with highest positive predictive values were, excluding parental chromosome rearrangement, increased nuchal translucency (9.2%) and ultrasound abnormalities (6.6%). In conclusion, performing the karyotype on amniotic fluid samples is a good method for the detection of chromosome abnormalities during pregnancy. The number of cytogenetic studies on amniotic fluid has now decreased, however, due to the implementation of first trimester prenatal screening for the detection of Down syndrome, which allows karyotyping on chorionic villus samples. Our results also show that both ultrasound abnormalities and increased nuchal translucency are excellent clinical indicators for fetal chromosome abnormality. Copyright © 2011 Elsevier Ireland Ltd. All rights reserved.

  5. Atmospheric and climatic consequences of a major nuclear war: Results of recent research

    International Nuclear Information System (INIS)

    Golitsyn, G.S.; MacCracken, M.C.

    1987-09-01

    During the last several years, comprehensive three-dimensional atmospheric circulation models, including detailed parametric formulations of a wide range of climatologically significant processes, have been applied to study the potential consequences of a major nuclear war involving the injection of smoke which could result from the large-scale fires ignited by such an exchange. For plausible smoke injections during the warm season of the year, all model calculations suggest that a significant climatic perturbation would result. In the lower range of smoke injection scenarios (producing of order 10 Tg of highly carbonaceous smoke), smoke would act primarily to inhibit convection and rainfall, especially over land areas, including possibly some disruption of the summer monsoon. The upper range of smoke scenarios (of order 100 Tg of highly carbonaceous smoke) would cause not only rapid and sharp decreases in land temperature and precipitation (a mid-latitude average land-temperature drop of the order of 20 0 C, up to perhaps twice this amount in continental interiors), but also seems likely to leave enough smoke in the atmosphere to persist into the following warm season, inducing a cooling of several degrees

  6. Evaluation of the CDTN's cementation facility using the results obtained in two different sizes: laboratory and facility

    International Nuclear Information System (INIS)

    Haucz, Maria Judite A.; Calabria, Jaqueline A. Almeida; Tello, Cledola Cassia O.; Candido, Francisco Donizete; Seles, Sandro Rogerio Novaes

    2011-01-01

    At CDTN R and D activities generate low-level radioactive wastes, among them the aqueous liquid ones, which need special attention due to their volumes. The usual treatment for these wastes is the volume reduction process using chemicals in order to change the radionuclides of the waste to an insoluble form. The resultant sludge is incorporated into cement in 200-liter drums using an in-line batch mixing system (CDTN Cementation Facility). The process parameters and solidified product quality are evaluated at the Cementation Laboratory (LABCIM), where tests are carried out to determine the viscosity, set time and density of the paste. In addition of the visual examination, compressive strength test and density are also established in the solidified product. In the cementation facility some pastes are also prepared for the immobilization of non-compactable waste, such as dump, scrap metal, wood, and other ones. This paper aims to present the study comparing the results of tests done in the pastes and products prepared in LABCIM and the ones obtained in CDTN's cementation facility, in order to check the efficiency of the cementation system. (author)

  7. Evaluation of the CDTN cementation facility using the results obtained in two different sizes: laboratory and facility

    International Nuclear Information System (INIS)

    Haucz, Maria Judite A.; Calabria, Jaqueline A. Almeida; Tello, Cledola Cassia O.; Candido, Francisco Donizete; Seles, Sandro Rogerio Novaes

    2011-01-01

    At CDTN R and D activities generate low-level radioactive wastes, among them the aqueous liquid ones, which need special attention due to their volumes. The usual treatment for these wastes is the volume reduction process using chemicals in order to change the radionuclides of the waste to an insoluble form. The resultant sludge is incorporated into cement in 200-liter drums using an in-line batch mixing system (CDTN Cementation Facility). The process parameters and solidified product quality are evaluated at the Cementation Laboratory (LABCIM), where tests are carried out to determine the viscosity, set time and density of the paste. In addition of the visual examination, compressive strength test and density are also established in the solidified product. In the cementation facility some pastes are also prepared for the immobilization of non-compactable waste, such as dump, scrap metal, wood, and other ones. This paper aims to present the study comparing the results of tests done in the pastes and products prepared in LABCIM and the ones obtained in CDTN's cementation facility, in order to check the efficiency of the cementation system. (author)

  8. Decontamination in preparation for dismantlement - AREVA's chemical decontamination technologies, projects performed and results obtained in the period 2011-2016

    International Nuclear Information System (INIS)

    Topf, C.; Sempere Belda, L.

    2017-01-01

    As a consequence of the nuclear phase-out decreed by the German government, several nuclear power plants in the country have already ceased operation. The remaining ones will cease operation by 2022. This has turned Germany into one of the most active regions worldwide in the field of nuclear decommissioning, with new and emerging technologies being deployed on the field, and already preexisting technologies being put to the test, optimized and developed into full maturity. The chemistry services division of AREVA GmbH has already performed 5 Full System Decontaminations (FSD) in preparation for decommissioning in this period - three in PWRs and two in BWRs - along with other international projects of relevance for decommissioning operations. During a FSD, the complete primary circuit of a nuclear power plant including auxiliary systems is subject to a chemical treatment; designed to remove radioactive matter accumulated onto system surfaces during operation. Through the effective removal of this radioactive accumulations contact dose rates on the different components of the primary circuit can be consistently reduced by factors larger than 50. This results in much lower ambient dose rates and, hence, in very significant dose savings for subsequent decommissioning activities. Additionally, dismantlement operations of large components are considerably simplified and can be performed under conditions that wouldn't have been possible before. The project specific objectives and challenges, the technologies employed, and the results obtained are presented and commented here. (authors)

  9. Biomonitoring of heavy metal deposition in the south Ural region: some preliminary results obtained by nuclear and related techniques

    International Nuclear Information System (INIS)

    Frontas'eva, M.V.; Steinnes, E.; Lyapunov, S.M.; Cherchintsev, V.D.; Smirnov, L.I.

    1999-01-01

    The first results are reported from the analysis of feather mosses used to study heavy metal atmospheric deposition in the vicinity of Magnitogorsk, the center of the steel industry in Russia. Moss samples collected at sites 30 km to the north-west of the industry were analyzed by instrumental neutron activation analysis using epithermal neutrons (ENAA), Results for a total of 38 elements are reported, including Pb, Cd, and Cu determined by atomic absorption spectroscopy (AAS). The element concentrations in moss samples from this work are compared with relevant literature data for strongly polluted areas in Central and Northern Europe and background values from Norway obtained by the same biomonitoring technique. The concentrations of Sb in the examined area are the highest ever reported for mosses, and also levels of Fe, Cr, and V are found to be particularly high. A scanning electron microscope connected to an XRF analyzer (SEM-XRF) was used to examine the surface of the moss samples. Photographs of identified iron spherules along with other aerosol particles made at magnification of 3500 to 5000 times and corresponding XRF analyses verifying the nature of typical particles are presented

  10. How many replicate tests do I need?$-$ Variability of cookstove performance and emissions has implications for obtaining useful results

    Energy Technology Data Exchange (ETDEWEB)

    Wang, Yungang [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States). Environmental Energy Technologies Division; Sohn, Michael D. [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States). Environmental Energy Technologies Division; Gadgil, Ashok J. [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States). Environmental Energy Technologies Division; Wang, Yilun [ISO Innovative Analytics San Francisco, CA (United States); Lask, Kathleen M. [Univ. of California, Berkeley, CA (United States). College of Engineering Applied Science and Technology Program; Kirchstetter, Thomas W. [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States). Environmental Energy Technologies Division

    2013-02-01

    Almost half of the world’s population still cooks on biomass cookstoves of poor efficiency and primitive design, such as three stone fires (TSF). Emissions from biomass cookstoves contribute to adverse health effects and climate change. A number of “improved cookstoves” with higher energy efficiency and lower emissions have been designed and promoted across the world. During the design development, and for selection of a stove for dissemination, the stove performance and emissions are commonly evaluated, communicated and compared using the arithmetic average of replicate tests made using a standardized laboratory-based test, commonly the water boiling test (WBT). However, published literature shows different WBT results reported from different laboratories for the same stove technology. Also, there is no agreement in the literature on how many replicate tests should be performed to ensure “significance” in the reported average performance. This matter has not received attention in the rapidly growing literature on stoves, and yet is crucial for estimating and communicating the performance of a stove, and for comparing the performance between stoves. We present results of statistical analyses using data from a number of replicate tests of performance and emission of the Berkeley-Darfur Stove (BDS) and the TSF under well-controlled laboratory conditions. We observed moderate variability in the test results for the TSF and BDS when measuring several characteristics. Here we focus on two as illustrative: time-to-boil and PM2.5 (particulate matter less than or equal to 2.5 micrometers in diameter) emissions. We demonstrate that interpretation of the results comparing these stoves could be misleading if only a small number of replicates had been conducted. We then describe a practical approach, useful to both stove testers and designers, to assess the number of replicates needed to obtain useful data. Caution should be exercised in attaching high credibility to

  11. IRRITABLE MOOD IN ADULT MAJOR DEPRESSIVE DISORDER: RESULTS FROM THE WORLD MENTAL HEALTH SURVEYS

    Science.gov (United States)

    Kovess-Masfety, Viviane; Alonso, Jordi; Angermeyer, Matthias; Bromet, Evelyn; de Girolamo, Giovanni; de Jonge, Peter; Demyttenaere, Koen; Florescu, Silvia E.; Gruber, Michael J.; Gureje, Oye; Hu, Chiyi; Huang, Yueqin; Karam, Elie G.; Jin, Robert; Lépine, Jean-Pierre; Levinson, Daphna; McLaughlin, Katie A.; Medina-Mora, María E.; O’Neill, Siobhan; Ono, Yutaka; Posada-Villa, José A.; Sampson, Nancy A.; Scott, Kate M.; Shahly, Victoria; Stein, Dan J.; Viana, Maria C.; Zarkov, Zahari; Kessler, Ronald C.

    2014-01-01

    Background Although irritability is a core symptom of DSM-IV major depressive disorder (MDD) for youth but not adults, clinical studies find comparable rates of irritability between nonbipolar depressed adults and youth. Including irritability as a core symptom of adult MDD would allow detection of depression-equivalent syndromes with primary irritability hypothesized to be more common among males than females. We carried out a preliminary examination of this issue using cross-national community-based survey data from 21 countries in the World Mental Health (WMH) Surveys (n = 110,729). Methods The assessment of MDD in the WHO Composite International Diagnostic Interview includes one question about persistent irritability. We examined two expansions of the definition of MDD involving this question: (1) cases with dysphoria and/or anhedonia and exactly four of nine Criterion A symptoms plus irritability; and (2) cases with two or more weeks of irritability plus four or more other Criterion A MDD symptoms in the absence of dysphoria or anhedonia. Results Adding irritability as a tenth Criterion A symptom increased lifetime prevalence by 0.4% (from 11.2 to 11.6%). Adding episodes of persistent irritability increased prevalence by an additional 0.2%. Proportional prevalence increases were significantly higher, but nonetheless small, among males compared to females. Rates of severe role impairment were significantly lower among respondents with this irritable depression who did not meet conventional DSM-IV criteria than those with DSM-IV MDD. Conclusion Although limited by the superficial assessment in this single question on irritability, results do not support expanding adult MDD criteria to include irritable mood. PMID:23364997

  12. Seasonal differences in the subjective assessment of outdoor thermal conditions and the impact of analysis techniques on the obtained results

    Science.gov (United States)

    Kántor, Noémi; Kovács, Attila; Takács, Ágnes

    2016-11-01

    Wide research attention has been paid in the last two decades to the thermal comfort conditions of different outdoor and semi-outdoor urban spaces. Field studies were conducted in a wide range of geographical regions in order to investigate the relationship between the thermal sensation of people and thermal comfort indices. Researchers found that the original threshold values of these indices did not describe precisely the actual thermal sensation patterns of subjects, and they reported neutral temperatures that vary among nations and with time of the year. For that reason, thresholds of some objective indices were rescaled and new thermal comfort categories were defined. This research investigates the outdoor thermal perception patterns of Hungarians regarding the Physiologically Equivalent Temperature ( PET) index, based on more than 5800 questionnaires. The surveys were conducted in the city of Szeged on 78 days in spring, summer, and autumn. Various, frequently applied analysis approaches (simple descriptive technique, regression analysis, and probit models) were adopted to reveal seasonal differences in the thermal assessment of people. Thermal sensitivity and neutral temperatures were found to be significantly different, especially between summer and the two transient seasons. Challenges of international comparison are also emphasized, since the results prove that neutral temperatures obtained through different analysis techniques may be considerably different. The outcomes of this study underline the importance of the development of standard measurement and analysis methodologies in order to make future studies comprehensible, hereby facilitating the broadening of the common scientific knowledge about outdoor thermal comfort.

  13. Design, operational experiences and beam results obtained with the SNS H- ion source and LEBT at Berkeley Lab

    International Nuclear Information System (INIS)

    Keller, R.; Thomae, R.; Stockli, M.; Welton, R.

    2002-01-01

    The ion source and Low-Energy Transport (LEBT) system that will provide H - ion beams to the Spallation Neutron Source (SNS)** Front End and the accelerator chain have been developed into a mature unit that fully satisfies the operational requirements through the commissioning and early operating phases of SNS. Compared to the early R and D version, many features of the ion source have been improved, and reliable operation at 6% duty factor has been achieved producing beam currents in the 35-mA range and above. LEBT operation proved that the purely electrostatic focusing principle is well suited to inject the ion beam into the RFQ accelerator, including the steering and pre-chopping functions. This paper will discuss the latest design features of the ion source and LEBT, give performance data for the integrated system, and report on commissioning results obtained with the SNS RFQ and Medium-Energy Beam Transport (MEBT) system. Prospects for further improvements will be outlined in concluding remarks

  14. Gender differences in major depressive disorder : Results from the Netherlands study of depression and anxiety

    NARCIS (Netherlands)

    Schuch, Jerome J. J.; Roest, Annelieke M.; Nolen, Willem A.; Penninx, Brenda W. J. H.; de Jonge, Peter

    Background: Although an overall gender difference in prevalence of major depressive disorder (MDD) has been well established, several questions concerning gender differences in the clinical manifestation of depression remain. This study aims to identify gender differences in psychopathology,

  15. Solar heating by radiant floor: Experimental results and emission reduction obtained with a micro photovoltaic–heat pump system

    International Nuclear Information System (INIS)

    Izquierdo, M.; Agustín-Camacho, P. de

    2015-01-01

    Highlights: • This work presents a PVT multicrystalline solar heating system for buildings. • The PV DC electricity generated was converted to AC to drive an air–water heat pump. • Experimental results obtained from December 1, 2012 to April 30, 2013 are detailed. • An environmental study is also presented. - Abstract: An experimental research with a solar photovoltaic thermal (PVT) micro grid feeding a reversible air–water, 6 kW heating capacity heat pump, has been carried out from December 2012 to April 2013. Its purpose is to heat a laboratory that is used as a house prototype for the study of heating/cooling systems. It was built in accordance with the 2013 Spanish CTE, and has an area of 35 m 2 divided into two internal rooms: one of them housing the storage system, the solar controller, the inverter and the control system; the other one is occupied by three people. Its main thermal characteristics are: UA = 125 W/°C and a maximum thermal load about 6.0 kW at the initial time. The PVT field consists of 12 modules, with a total area of 15.7 m 2 and useful area of 14 m 2 . Each module is composed of 48 polycrystalline silicon cells of 243.4 cm 2 , which with a nominal efficiency 14% can generate a power of 180 W, being the total nominal power installed 2.16 kW. The PV system stores electricity in 250 Ah batteries from where is converted from DC to AC through a 3.0 kW inverter that feeds the heat pump. This works supplying 840 l/h of hot water at 35–45 °C to the radiant floor. The data storing system is recording variables such as solar radiation; temperatures; input power to batteries; heat produced; heat transferred by the radiant floor; heat pump’s COP; isolated ratio; and solar fraction. The objective of this work is to present and discuss the experimental results and the emission reduction of CO 2 obtained during the period from 01/12/2012 to 30/04/2013, including the detailed results of two representative days of Madrid’s climate: 28

  16. Results from the first year as a major trauma radiology unit in the UK

    International Nuclear Information System (INIS)

    Adiotomre, A.; Chopra, A.; Kirwadi, A.; Kotnis, N.

    2014-01-01

    Aim: To record and analyse data from all facets of practice in the first year as a newly set-up major trauma centre radiology department. Materials and methods: Retrospective analysis of all patients who underwent whole-body computed tomography (WBCT) for suspected polytrauma over a 1 year period was performed. The mechanism, the time of day, the number of body parts injured, the type of injuries, and resulting surgical or radiological interventions were recorded. Also recorded was the time from the CT examination to the formal report. Where applicable, the consultant-verified reports were cross-referenced with the out-of-hours registrar reports to assess for discrepancies. Results: Two hundred and one patients underwent WBCT for suspected polytrauma. Sixty-four percent (128/201) of WBCT examinations were performed “out-of-hours”. Fifty-seven percent (115/201) were road traffic accidents (RTAs), 33% (66/201) were falls, and 6% (12/201) were assaults. At WBCT, 31% (63/201) had no injuries; 27% (54/201) had injury to one body area; 21% (43/201) had injury to two areas; and 20% (41/201) had injury to three or more areas. Nineteen percent (39/201) required urgent radiological or surgical intervention. The mean time from end-of-CT to a formal report was 27 min. There were discrepancies between consultant reports and registrar reports in 22% (31/142) of cases; 1% (2/142) led to a change in acute management. Conclusion: Based on our early experiences, nearly one-third of patients who undergo a WBCT scan for suspected polytrauma, will have no acute injury at WBCT. One-fifth of patients in our study required emergency surgical or radiological intervention for acute injuries found on WBCT. A low discrepancy rate was found between on-call registrar reports and the consultant-verified reports. - Highlights: • Almost one-third of patients with clinically suspected polytrauma had no acute injury at whole body CT. • One-fifth of clinically suspected polytrauma patients

  17. Major results and lessons learned for performance assessments of spent fuel geological disposal: the SPA project

    International Nuclear Information System (INIS)

    Baudoin, P.; Serres, C.; Certes, C.; Gay, D.

    2001-01-01

    This paper presents a summary of the results obtained in the framework of the SPA (spent fuel disposal performance assessment) project. The project was undertaken by ENRESA, E; GRS, D; IPSN, F; NRG, NL; SCK.CEN, B and VTT, FIN between May 1996 and April 1999. Devoted to the study of spent fuel disposal in various host rock formations (clay, crystalline rocks and salt formation), it notably had the objective to evaluate the long-term performance of different repository systems and to identify the most influential elements. The variety of concepts, sites and scenarios considered in the framework of this project provides a wide range of information from which some general conclusions can be drawn. Focusing on the work done in the case of granite host rock formations, this paper describes the various approaches adopted and states the main sources of differences. It particularly stresses the differences related to the geosphere and biosphere modelling. For the geosphere modelling, ENRESA, GRS and VTT use one dimensional discrete approaches to model the migration of contaminants through the geosphere taking into account for matrix diffusion, whereas IPSN uses a three dimensional continuum approach based on a single porosity model. The comparison of the biosphere conversion factors shows the high influence on the calculated radionuclide dose contributions that can results from biosphere modelling assumptions. It notably points out the differences existing between a simplified ''water drinking'' approach as implemented by VTT and a more classical one in which a wider range of exposure pathways are taken into account. (orig.)

  18. The effects of metal ion PCR inhibitors on results obtained with the Quantifiler(®) Human DNA Quantification Kit.

    Science.gov (United States)

    Combs, Laura Gaydosh; Warren, Joseph E; Huynh, Vivian; Castaneda, Joanna; Golden, Teresa D; Roby, Rhonda K

    2015-11-01

    Forensic DNA samples may include the presence of PCR inhibitors, even after extraction and purification. Studies have demonstrated that metal ions, co-purified at specific concentrations, inhibit DNA amplifications. Metal ions are endogenous to sample types, such as bone, and can be introduced from environmental sources. In order to examine the effect of metal ions as PCR inhibitors during quantitative real-time PCR, 2800 M DNA was treated with 0.0025-18.750 mM concentrations of aluminum, calcium, copper, iron, nickel, and lead. DNA samples, both untreated and metal-treated, were quantified using the Quantifiler(®) Human DNA Quantification Kit. Quantification cycle (Cq) values for the Quantifiler(®) Human DNA and internal PCR control (IPC) assays were measured and the estimated concentrations of human DNA were obtained. Comparisons were conducted between metal-treated and control DNA samples to determine the accuracy of the quantification estimates and to test the efficacy of the IPC inhibition detection. This kit is most resistant to the presence of calcium as compared to all metals tested; the maximum concentration tested does not affect the amplification of the IPC or quantification of the sample. This kit is most sensitive to the presence of aluminum; concentrations greater than 0.0750 mM negatively affected the quantification, although the IPC assay accurately assessed the presence of PCR inhibition. The Quantifiler(®) Human DNA Quantification Kit accurately quantifies human DNA in the presence of 0.5000 mM copper, iron, nickel, and lead; however, the IPC does not indicate the presence of PCR inhibition at this concentration of these metals. Unexpectedly, estimates of DNA quantity in samples treated with 18.750 mM copper yielded values in excess of the actual concentration of DNA in the samples; fluorescence spectroscopy experiments indicated this increase was not a direct interaction between the copper metal and 6-FAM dye used to label the probe that

  19. Uncertainty and Sensitivity Analysis Results Obtained in the 1996 Performance Assessment for the Waste Isolation Pilot Plant

    Energy Technology Data Exchange (ETDEWEB)

    Bean, J.E.; Berglund, J.W.; Davis, F.J.; Economy, K.; Garner, J.W.; Helton, J.C.; Johnson, J.D.; MacKinnon, R.J.; Miller, J.; O' Brien, D.G.; Ramsey, J.L.; Schreiber, J.D.; Shinta, A.; Smith, L.N.; Stockman, C.; Stoelzel, D.M.; Vaughn, P.

    1998-09-01

    The Waste Isolation Pilot Plant (WPP) is located in southeastern New Mexico and is being developed by the U.S. Department of Energy (DOE) for the geologic (deep underground) disposal of transuranic (TRU) waste. A detailed performance assessment (PA) for the WIPP was carried out in 1996 and supports an application by the DOE to the U.S. Environmental Protection Agency (EPA) for the certification of the WIPP for the disposal of TRU waste. The 1996 WIPP PA uses a computational structure that maintains a separation between stochastic (i.e., aleatory) and subjective (i.e., epistemic) uncertainty, with stochastic uncertainty arising from the many possible disruptions that could occur over the 10,000 yr regulatory period that applies to the WIPP and subjective uncertainty arising from the imprecision with which many of the quantities required in the PA are known. Important parts of this structure are (1) the use of Latin hypercube sampling to incorporate the effects of subjective uncertainty, (2) the use of Monte Carlo (i.e., random) sampling to incorporate the effects of stochastic uncertainty, and (3) the efficient use of the necessarily limited number of mechanistic calculations that can be performed to support the analysis. The use of Latin hypercube sampling generates a mapping from imprecisely known analysis inputs to analysis outcomes of interest that provides both a display of the uncertainty in analysis outcomes (i.e., uncertainty analysis) and a basis for investigating the effects of individual inputs on these outcomes (i.e., sensitivity analysis). The sensitivity analysis procedures used in the PA include examination of scatterplots, stepwise regression analysis, and partial correlation analysis. Uncertainty and sensitivity analysis results obtained as part of the 1996 WIPP PA are presented and discussed. Specific topics considered include two phase flow in the vicinity of the repository, radionuclide release from the repository, fluid flow and radionuclide

  20. Uncertainty and Sensitivity Analysis Results Obtained in the 1996 Performance Assessment for the Waste Isolation Pilot Plant

    International Nuclear Information System (INIS)

    Bean, J.E.; Berglund, J.W.; Davis, F.J.; Economy, K.; Garner, J.W.; Helton, J.C.; Johnson, J.D.; MacKinnon, R.J.; Miller, J.; O'Brien, D.G.; Ramsey, J.L.; Schreiber, J.D.; Shinta, A.; Smith, L.N.; Stockman, C.; Stoelzel, D.M.; Vaughn, P.

    1998-01-01

    The Waste Isolation Pilot Plant (WPP) is located in southeastern New Mexico and is being developed by the U.S. Department of Energy (DOE) for the geologic (deep underground) disposal of transuranic (TRU) waste. A detailed performance assessment (PA) for the WIPP was carried out in 1996 and supports an application by the DOE to the U.S. Environmental Protection Agency (EPA) for the certification of the WIPP for the disposal of TRU waste. The 1996 WIPP PA uses a computational structure that maintains a separation between stochastic (i.e., aleatory) and subjective (i.e., epistemic) uncertainty, with stochastic uncertainty arising from the many possible disruptions that could occur over the 10,000 yr regulatory period that applies to the WIPP and subjective uncertainty arising from the imprecision with which many of the quantities required in the PA are known. Important parts of this structure are (1) the use of Latin hypercube sampling to incorporate the effects of subjective uncertainty, (2) the use of Monte Carlo (i.e., random) sampling to incorporate the effects of stochastic uncertainty, and (3) the efficient use of the necessarily limited number of mechanistic calculations that can be performed to support the analysis. The use of Latin hypercube sampling generates a mapping from imprecisely known analysis inputs to analysis outcomes of interest that provides both a display of the uncertainty in analysis outcomes (i.e., uncertainty analysis) and a basis for investigating the effects of individual inputs on these outcomes (i.e., sensitivity analysis). The sensitivity analysis procedures used in the PA include examination of scatterplots, stepwise regression analysis, and partial correlation analysis. Uncertainty and sensitivity analysis results obtained as part of the 1996 WIPP PA are presented and discussed. Specific topics considered include two phase flow in the vicinity of the repository, radionuclide release from the repository, fluid flow and radionuclide

  1. Outcome measurements in major trauma--results of a consensus meeting.

    Science.gov (United States)

    Ardolino, A; Sleat, G; Willett, K

    2012-10-01

    The NHS Outcomes Framework for England has identified recovery from major injury as an important clinical area. At present, there are no established outcome indicators. As more patients survive major trauma, outcomes will need to be measured in terms of morbidity and not mortality alone. To make recommendations for a selection of outcome measures that could be integrated into National Clinical Audit data collection and form part of clinical governance requirements for Regional Trauma Networks (RTNs) and measures by which RTNs are held to account by government. Specific focus was given to acute care and rehabilitation for both adults and children. A Multiprofessional, multidisciplinary expert group reviewed the current evidence on outcome measures for major trauma in the adult and children's populations, informed by a systematic review carried out jointly by the Trauma Audit and Research Network (TARN) and the Cochrane Injuries Group. A structured discussion covered functional and quality of life outcome measures as well as patient experience and indicators such as return to work, education and social dependency. For the adult population the group agreed with the in-hospital performance and hospital discharge measures recommended in the TARN and Cochrane systematic review. Concerning longer-term outcome indicators, the group suggested the use of the Glasgow Outcome Scale - Extended (GOS-E) and European Quality of Life 5D (EQ-5D) with consideration to be given to the World Health Organisation Quality of Life survey (WHO-QoL). For patients who had ongoing inpatient rehabilitation needs the group thought the measurement of the Rehabilitation Complexity Scale (RCS) and Functional Independence Measure (FIM) were important in total brain injury and, the American Spinal Injury Association Impairment Scale (ASIA) and Spinal Cord Independence Measure (SCIM) in spinal cord injury. For children the group recommended the use of the King's Outcome Scale for Childhood Head Injury

  2. Results of environmental radiation monitoring and meteorology measurements (material prepared for obtaining the licence for RA reactor experimental operation)

    International Nuclear Information System (INIS)

    1980-10-01

    According to the demands for obtaining the licence for restarting the Ra reactor and the experimental operation this document includes the radiation monitoring measured data in the working space and environment of the RA reactor, i.e. Boris Kidric Institute. The meteorology measured data are included as well. All the measurements are performed according to the radiation protection program applied actually from the first reactor start-up at the end of 1959 [sr

  3. Obtaining a citric tristeza virus p65 protein antibody and preliminary results of p65 in vivo expression

    Directory of Open Access Journals (Sweden)

    Yanneth Torres

    2003-07-01

    Full Text Available The citric tristeza virus (CTV belongs to the Closteroviridae family which indudes the only vegetal viruses possessing genes homologous to HSP70 thermal cellular shock proteins in their genome. Such is the case of the gene encoding for the CTV p65 protein which presents high homology with the HSP70 protein family. It has been shown recently that HSP70h viral proteins (such as CTV p65 are involved both in viral assembly, as a microtubule binding protein, and in cell-cell movement. Since CTV is the most deleterious citrus pathogen, understanding this protein's role in the pathogenesis process is important. Rabbits were immunised with four synthetic peptides (corresponding to CTV p65 thermal shock protein's carboxyl-terminal region to obtain polyclonal antibodies. All the peptides used were immunogenic, even though two of them showed greater response. Whilst none of the antibodies obtained reacted to non-infected plant extract, the p65 proteins was detected in extracts taken from citric plants infected with CTV Based on the antibody's reaction to two Colombian isolates having different serological characteristics, the p65 antibody's immunological behaviour appeared to be independent of the symptomatic severity of the CTV isolates. It was shown that the ORF encoded for the HSP70 homologue in CTV was expressed in vivo, even though the p65 antibody was only detected in concentrated protein extracts taken from infected plants, supporting reports from other studies that the concentration of this protein in plants infected with CTV is low. This is the first time that a polyclonal CTV antibody has been obtained in Colombia against p65 (a protein intervening in viral assembly and movement. Adapting a technique for obtaining p65 antibodies by using synthetic peptides as immunogens could be useful in the future for detecting or diagnosing p65 proteins present in different Colombian CTV isolates, especially in developing studies contributing towards greater

  4. Visualization of atomic distances at the 1MV electron microscope: first results obtained on the Grenoble 1MV microscope

    International Nuclear Information System (INIS)

    Bourret, A.

    1975-01-01

    Practical and theoretical conditions for obtaining high resolution lattice images are presented. The use of a high voltage electron microscope is particularly powerful to visualize distances smaller than 3A. A 2A resolution test on (200) gold planes has been carried out on the Grenoble 1MV microscope. It would be possible at this level to study the crystalline defects such as dislocations or grain boundaries [fr

  5. Shaking table testing of a HTGR reactor core, comparison with the results obtained using a nonlinear mathematical model

    International Nuclear Information System (INIS)

    Berriaud, C.; Cebe, E.; Livolant, M.; Buland, P.

    1975-01-01

    Two series of horizontal tests have been performed at Saclay on the shaking table VESUVE: sinusoidal test and time history response. Sinusoidal tests have shown the strongly nonlinear dynamic behavior of the core. The resonant frequency of the core is dependent on the level of the excitation. These phenomena have been explained by a computer code, which is a lumped mass nonlinear model. El Centro time history displacement at the level of PCRV was reproduced on the shaking table. The analytical model was applied to this excitation and good comparison was obtained for forces and velocities [fr

  6. Endocrinopathies in Turkish children with Beta thalassemia major: results from a single center study.

    Science.gov (United States)

    Isik, Pamir; Yarali, Nese; Tavil, Betül; Demirel, Fatma; Karacam, Gülşah Bayram; Sac, Rukiye Unsal; Fettah, Ali; Ozkasap, Serdar; Kara, Abdurrahman; Tunc, Bahattin

    2014-10-01

    The endocrinological complications in β-thalassemia major patients do affect the life quality to a large extend. In this study, the endocrinological complications of 47 β-thalassemia patients, who have been followed-up at our hospital's pediatric hematology department, were evaluated. Out of β-thalassemia major cases included to this study, the 55.3% was male and 44.7% was female. The patients' mean levels of ferritin, whose mean age was 10.0 ± 4.5 years (2-20 years), were 2497 ± 1469 ng/mL (472-8558 ng/mL). At least one endocrinological pathology in 27 out of 47 (57.4%) and more than one endocrinological pathology in 14 out of 47 (29.7%) thalassemia patients were observed. The most frequently observed complication in followed-up cases was vitamin D insufficiency and deficiency (78.2%). The other complications in decreasing order were pubertal failure (41.6%), growth retardation (25.5%), decreased bone-mineral density (22.2%), secondary hyperparathyroidism (11.5%), overt hypothyroidism (4.25%), subclinical hypothyroidism (2.12%), and impaired glucose tolerance (2.12%). There was no statistically significant difference between serum mean ferritin level and endocrin complications (P > .05). Four patients (8.5%) had decreased signal intensity in pituitary magnetic resonance imaging (MRI) but this finding was not associated with ferritin levels (P = .87). MRI parameters were similar between patients with and without gonadal dysfunction. Mean height of the pituitary gland was 4.98 ± 1.1 mm (3-9 mm) and this was similar to those normal values in the literature. Ferritin levels were not correlated with pituitary height (P > .05). Beta thalassemia major, having the potential of leading to multisystemic complications, is a chronic disease that should be treated and followed-up by a multidisciplinary approach. Due to frequently encountered endocrinological complications, beta thalassemic patients should be followed-up regularly by hematology and endocrinology

  7. Psychosocial work factors, major depressive and generalised anxiety disorders: results from the French national SIP study.

    Science.gov (United States)

    Murcia, Marie; Chastang, Jean-François; Niedhammer, Isabelle

    2013-04-25

    Anxiety and depression are prevalent mental disorders in working populations. The risk factors of these disorders are not completely well known. Developing knowledge on occupational risk factors for mental disorders appears crucial. This study investigates the association between various classical and emergent psychosocial work factors and major depressive and generalised anxiety disorders in the French working population. The study was based on a national random sample of 3765 men and 3944 women of the French working population (SIP 2006 survey). Major Depressive Disorder (MDD) and Generalised Anxiety Disorder (GAD) were measured using a standardised diagnostic interview (MINI). Occupational factors included psychosocial work factors as well as biomechanical, physical, and chemical exposures. Adjustment variables included age, occupation, marital status, social support, and life events. Multivariate analysis was performed using logistic regression analysis. Low decision latitude, overcommitment, and emotional demands were found to be risk factors for both MDD-GAD among both genders. Other risk factors were observed: high psychological demands, low reward, ethical conflict, and job insecurity, but differences were found according to gender and outcome. Significant interaction terms were observed suggesting that low decision latitude, high psychological demands, and job insecurity had stronger effects on mental disorders for men than for women. Given the cross-sectional study design, no causal conclusion could be drawn. This study showed significant associations between classical and emergent psychosocial work factors and MDD-GAD. Preventive actions targeting various psychosocial work factors, including emergent factors, may help to reduce mental disorders at the workplace. Copyright © 2012 Elsevier B.V. All rights reserved.

  8. An easy way to obtain strong duality results in linear, linear semidefinite and linear semi-infinite programming

    NARCIS (Netherlands)

    Pop, P.C.; Still, Georg J.

    1999-01-01

    In linear programming it is known that an appropriate non-homogeneous Farkas Lemma leads to a short proof of the strong duality results for a pair of primal and dual programs. By using a corresponding generalized Farkas lemma we give a similar proof of the strong duality results for semidefinite

  9. Recent results from Pb - Au collisions at 158 GeV/c per nucleon obtained with the CERES spectrometer

    CERN Document Server

    Agakichiev, G; Baur, R; Braun-Munzinger, P; Ceretto, F; Cherlin, A; Drees, A; Esumi, S C; Faschingbauer, U; Fraenkel, Zeev; Glässel, P; Hering, G; Holl, P; Jung, C; Lenkeit, B C; Marin, A; Messer, M; Miskowiec, D; Panebratsev, Yu A; Pfeiffer, A; Rak, J; Ravinovich, I; Razin, S V; Rehak, P; Richter, M; Saveljic, N; Schmitz, W; Schükraft, Jürgen; Seipp, W; Shimansky, S S; Slivova, J; Socol, E; Specht, H J; Stachel, J J; Tserruya, Itzhak; Ullrich, T S; Voigt, C A; Voloshin, S A; Weber, C; Wessels, J P; Wienold, T; Wurm, J P; Yurevich, V I

    1999-01-01

    During the 1996 lead run time, CERES has accumulated 42 million events, corresponding to a factor of 5 more statistics than in 1995 and 2.5 million events of a special photon-run. We report on the results of the low-mass e/sup +/e/sup -/-pair analysis. Since the most critical item is the poor signal-to-background ratio we also discuss the understanding of this background, in absolute terms, with the help of a detailed Monte Carlo simulation. We show preliminary results of the photon analysis and summarize the results of the hadron analysis preliminarily reported on already at QM'97. (19 refs) .

  10. The French program on the spent nuclear fuel long term evolution: Major results, uncertainties and new requirements

    International Nuclear Information System (INIS)

    Ferry, Cecile; Poinssot, Christophe; Gras, Jean-Marie

    2006-01-01

    conditions; oxidation kinetics of UO 2 and spent fuel are assessed by coupling a microscopic approach with macroscopic classical methods; - in water, this boundary condition corresponds to the nominal scenario after the breaching of the canister during geological disposal; in this case, the effect of water a radiolysis on the spent fuel matrix dissolution is investigated. An overview of the state of knowledge on the long-term behaviour of spent fuel under these various conditions has been provided by Ferry et al. (2005). This report constitutes the scientific synthesis due at the term of the law. This state of the art was derived from the results obtained under the PRECCI project as well as from a review of the literature and some of the data issued from the 5. PRDC European project 'Spent Fuel Stability under Repository Conditions' (Poinssot et al, 2005). Regarding these results, this paper presents for each initial operational question and concept, the main scientific issues, the major results obtained since 1999, and the remaining uncertainties. The new requirements in the frame of a broader context which includes transport and in-pool storage issues are also identified. The contents of this paper is as follows: 1 Introduction; 2 The retrievability of spent fuel assemblies after storage; 2.1 Main scientific issues; 2.2 Major results; 2.2.1 Mechanical evolution of the cladding and structural materials; 2.2.2 Specific case of the defected fuel rods - Evolution of the spent fuel pellets; 2.3 Remaining uncertainties and new requirements for each operational context; 3 The treatment of spent fuel after a long period of storage; 3.1 Main scientific issues; 3.2 Major results; 3.3 Remaining uncertainties and new requirements; 4 The definition of the radionuclide source terms; 4.1 Main scientific issues; 4.2 Major results; 4.3 Remaining uncertainties and new requirements for each operational context; 5 The compatibility between dry storage and subsequent disposal; 5.1 Main

  11. Study of the nuclear multifragmentation: recent results obtained with the INDRA detector in the intermediate energy domain

    International Nuclear Information System (INIS)

    Saint-Laurent, F.

    1994-01-01

    The new 4π multidetector INDRA, designed for the study of hot nuclear systems decaying by multifragmentation, is available for experiments since the beginning of 1993. First results emphasize its very high detection capabilities. Preliminary results on multiplicity distributions and elemental charge distributions in the most violent collisions for the 36 Ar + 58 Ni and 129 Xe + nat Sn systems are presented. (author) 5 figs., 22 refs

  12. Main results obtained in France in the development of the gaseous diffusion process for uranium isotope separation

    International Nuclear Information System (INIS)

    Frejacques, C.; Bilous, O.; Dixmier, J.; Massignon, D.; Plurien, P.

    1958-01-01

    The main problems which occur in the study of uranium isotope separation by the gaseous diffusion process, concern the development of the porous barrier, the corrosive nature of uranium hexafluoride and also the chemical engineering problems related to process design and the choice of best plant and stage characteristics. Porous barriers may be obtained by chemical attack of non porous media or by agglomeration of very fine powders. Examples of these two types of barriers are given. A whole set of measurement techniques were developed for barrier structure studies, to provide control and guidance of barrier production methods. Uranium hexafluoride reactivity and corrosive properties are the source of many difficult technological problems. A high degree of plant leak tightness must be achieved. This necessity creates a special problem in compressor bearing design. Barrier lifetime is affected by the corrosive properties of the gas, which may lead to a change of barrier structure with time. Barrier hexafluoride permeability measurements have helped to make a systematic study of this point. Finally an example of a plant flowsheet, showing stage types and arrangements and based on a minimisation of enriched product costs is also given as an illustration of some of the chemical engineering problems present. (author) [fr

  13. Recovery in patients with major depressive disorder (MDD): results of a 6-month, multinational, observational study.

    Science.gov (United States)

    Novick, Diego; Montgomery, William; Vorstenbosch, Ellen; Moneta, Maria Victoria; Dueñas, Héctor; Haro, Josep Maria

    2017-01-01

    Not all individuals treated for major depressive disorder (MDD) achieve recovery. This observational study examined the recovery rates in MDD patients and the patient characteristics associated with achieving recovery in a naturalistic clinical setting. Recovery was defined as having both clinical and functional remission. Data for this post hoc analysis were taken from a 24-week prospective, observational study that involved 1,549 MDD patients. Clinical remission was assessed using the 16-item Quick Inventory of Depressive Symptomatology Self-Report and functional remission through the Sheehan Disability Scale and no days of reduced productivity in the previous week. Generalized estimating equation regression models were used to examine the baseline factors associated with recovery during follow-up. Clinical and functional remission was achieved in 70.6% and 56.1% of the MDD patients, respectively. MDD patients who achieved recovery (52.1%) were significantly less likely to have impaired levels of functioning, concurrent medical or psychiatric conditions, low levels of education, or nonadherence to therapy at follow-up. The level of functioning during the index episode seems to be a better predictor of recovery than symptom severity. Therefore, the level of functioning should be considered while determining recovery from depression.

  14. Friction and wear in liquid-metal systems: comparability problems of test results obtained from different test facilities

    International Nuclear Information System (INIS)

    Wild, E.; Mack, K.J.

    1976-01-01

    Operational induced relative movements take place between contacting components in the core region of sodium cooled reactors. To ensure reliable long term functioning of such friction loaded components, materials are needed with good sliding properties and high wear resistance. Therefore, tribological properties of material combinations in liquid metal have been investigated experimentally for many years at various research establishments. However, despite identical boundary conditions, the comparison of results published does not yield a satisfactory agreement. The cause must be seen in the individual design and concept of the test sections used. This discrepancy was investigated. The results show that the elasticity, mass movement, and relative motion characteristic to the system prove to be the most important criteria influencing the test results

  15. A new warfarin dosing algorithm including VKORC1 3730 G > A polymorphism: comparison with results obtained by other published algorithms.

    Science.gov (United States)

    Cini, Michela; Legnani, Cristina; Cosmi, Benilde; Guazzaloca, Giuliana; Valdrè, Lelia; Frascaro, Mirella; Palareti, Gualtiero

    2012-08-01

    Warfarin dosing is affected by clinical and genetic variants, but the contribution of the genotype associated with warfarin resistance in pharmacogenetic algorithms has not been well assessed yet. We developed a new dosing algorithm including polymorphisms associated both with warfarin sensitivity and resistance in the Italian population, and its performance was compared with those of eight previously published algorithms. Clinical and genetic data (CYP2C9*2, CYP2C9*3, VKORC1 -1639 G > A, and VKORC1 3730 G > A) were used to elaborate the new algorithm. Derivation and validation groups comprised 55 (58.2% men, mean age 69 years) and 40 (57.5% men, mean age 70 years) patients, respectively, who were on stable anticoagulation therapy for at least 3 months with different oral anticoagulation therapy (OAT) indications. Performance of the new algorithm, evaluated with mean absolute error (MAE) defined as the absolute value of the difference between observed daily maintenance dose and predicted daily dose, correlation with the observed dose and R(2) value, was comparable with or slightly lower than that obtained using the other algorithms. The new algorithm could correctly assign 53.3%, 50.0%, and 57.1% of patients to the low (≤25 mg/week), intermediate (26-44 mg/week) and high (≥ 45 mg/week) dosing range, respectively. Our data showed a significant increase in predictive accuracy among patients requiring high warfarin dose compared with the other algorithms (ranging from 0% to 28.6%). The algorithm including VKORC1 3730 G > A, associated with warfarin resistance, allowed a more accurate identification of resistant patients who require higher warfarin dosage.

  16. Cytogenetical effects of low doses: results obtained by N.N.Luchik and present-day problems

    International Nuclear Information System (INIS)

    Geras'kin, S.A.; Sevan'kaev, A.V.

    1996-01-01

    The analysis of present status of the problem of quantitative assessment of cytogenetic effects low is presented. The importance of works of N.V. Luchik is demonstrated for the development of this field of radiobiology. The results of the author's own experimental and theoretical research on the regularities of induction of cytogenetical damage by low doses of ionising radiation are presented

  17. Recovery in patients with major depressive disorder (MDD: results of a 6-month, multinational, observational study

    Directory of Open Access Journals (Sweden)

    Novick D

    2017-10-01

    Full Text Available Diego Novick,1 William Montgomery,2 Ellen Vorstenbosch,3 Maria Victoria Moneta,3 Héctor Dueñas,4 Josep Maria Haro3 1Eli Lilly and Company, Windlesham, Surrey, UK; 2Eli Lilly Australia Pty Ltd, West Ryde, NSW, Australia; 3Parc Sanitari Sant Joan de Déu, Fundació Sant Joan de Déu, CIBERSAM, Universitat de Barcelona, Barcelona, Spain; 4Eli Lilly de Mexico, Mexico City, Mexico Abstract: Not all individuals treated for major depressive disorder (MDD achieve recovery. This observational study examined the recovery rates in MDD patients and the patient characteristics associated with achieving recovery in a naturalistic clinical setting. Recovery was defined as having both clinical and functional remission. Data for this post hoc analysis were taken from a 24-week prospective, observational study that involved 1,549 MDD patients. Clinical remission was assessed using the 16-item Quick Inventory of Depressive Symptomatology Self-Report and functional remission through the Sheehan Disability Scale and no days of reduced productivity in the previous week. Generalized estimating equation regression models were used to examine the baseline factors associated with recovery during follow-up. Clinical and functional remission was achieved in 70.6% and 56.1% of the MDD patients, respectively. MDD patients who achieved recovery (52.1% were significantly less likely to have impaired levels of functioning, concurrent medical or psychiatric conditions, low levels of education, or nonadherence to therapy at follow-up. The level of functioning during the index episode seems to be a better predictor of recovery than symptom severity. Therefore, the level of functioning should be considered while determining recovery from depression. Keywords: remission, functional impairment, clinical remission, course of illness, disability, predictors

  18. Gender differences in major depressive disorder: results from the Netherlands study of depression and anxiety.

    Science.gov (United States)

    Schuch, Jérôme J J; Roest, Annelieke M; Nolen, Willem A; Penninx, Brenda W J H; de Jonge, Peter

    2014-03-01

    Although an overall gender difference in prevalence of major depressive disorder (MDD) has been well established, several questions concerning gender differences in the clinical manifestation of depression remain. This study aims to identify gender differences in psychopathology, treatment, and public health consequences in patients with MDD. Baseline data from the Netherlands Study of Depression and Anxiety (NESDA) were used, including 1115 participants (364 men, 751 women, mean age 41 years) with a DSM-IV diagnosis of current MDD. Characteristics studied included symptom profiles, comorbidity, treatment, and public health consequences. Women reported a younger age of onset of single (27.8 years vs. 31.6 years; p=0.001) and recurrent MDD (24.8 years vs. 27.6 years; p=0.014), a higher comorbidity of panic disorder with agoraphobia (24.9% vs. 17.3%; p=0.006) and life-time overall anxiety disorder (77.6% vs. 71.4%; p=0.029) than men. More men than women suffered from comorbid alcohol dependence or abuse (48.1% vs. 24.5%; pdepression in women (24.6% vs. 17.3%; p=0.009) was found. Women were treated more frequently by an alternative caretaker (20.6% vs. 14.8%; p=0.025), men more often in mental health care organizations (61.0% vs. 53.7%; p=0.025). No gender differences in frequency of medication use or counseling were found. Cross sectional design. Main gender differences in the clinical presentation of MDD concerned a younger age of onset, higher anxiety and lower alcohol use comorbidity and higher prevalence of atypical depression in women. These differences were accompanied by differences in health care use. Copyright © 2013 Elsevier B.V. All rights reserved.

  19. Reduced parahippocampal and lateral temporal GABAA-[11C]flumazenil binding in major depression: preliminary results

    International Nuclear Information System (INIS)

    Klumpers, Ursula M.H.; Veltman, Dick J.; Drent, Madeleine L.; Boellaard, Ronald; Lammertsma, Adriaan A.; Comans, Emile F.I.; Meynen, Gerben; Hoogendijk, Witte J.G.

    2010-01-01

    Major depressive disorder (MDD) has been related to both a dysfunctional γ-amino butyric acid (GABA) system and to hyperactivity of the hypothalamic-pituitary-adrenal axis (HPA). Although GABA has been suggested to inhibit HPA axis activity, their relationship has never been studied at the level of the central GABA A -benzodiazepine receptor in depressed patients or in relation to antidepressant treatment. Eleven depressed outpatients were compared, before and after treatment with citalopram, with nine age-matched healthy controls. The subjects were scanned using the positron emission tomography (PET) tracer [ 11 C]flumazenil ([ 11 C]FMZ). Parametric voxel-by-voxel Logan plots were compared with methods based on regions of interest (ROI), to provide volume of distribution (V T ) and binding potential (BP ND ) values. Plasma GABA levels were determined and a dexamethasone-corticotropin releasing hormone (DEX-CRH) test was performed. In MDD, parametric voxel-by-voxel Logan plots showed bilateral reduced [ 11 C]FMZ binding in the parahippocampal gyrus and right lateral superior temporal gyrus (p uncorrected ≤0.001). In the temporal area, [ 11 C]FMZ binding showed a strong inverse correlation with HPA axis activity. Plasma GABA did not discriminate MDD from controls, but correlated inversely with [ 11 C]FMZ binding in the right insula. Following treatment with citalopram, voxel-based analysis revealed reduced binding in the right lateral temporal gyrus and dorsolateral prefrontal cortex. The bilateral reduction in limbic parahippocampal and right temporal [ 11 C]FMZ binding found in MDD indicates decreased GABA A -benzodiazepine receptor complex affinity and/or number. The inverse relationship between GABA A binding in the temporal lobe and HPA axis activity, suggests that HPA axis hyperactivity is partly due to reduced GABA-ergic inhibition. (orig.)

  20. Detection of occlusal caries lesions using fluorescence: correlation between histology and obtained results for Diagnodent and spectroscopy

    International Nuclear Information System (INIS)

    Rocha-Cabral, Renata Maciel

    2006-01-01

    The aims of this study were to develop and test a method to detect caries lesions in vivo and in vitro, using a portable spectrometer (PS); to analyze the performance of PS as well as the commercial device Diagnodent (Dd); correlate them with the gold standard, their transversal section areas and lesions depth and between themselves. 66 occlusal pre-molars sites were examined in vivo with Dd. Sequentially, fluorescence (λexc ∼ 657 nm) was collected by an optical fiber, conducted to PS and then analyzed as spectra, which were normalized and had calculated the Ratios of their Areas Under the Curves (RAUC) of carious and sound tissues. Experiments were conducted in vitro in the same sites. Gold Standard was obtained by polarized light microscopy. Pearson correlation was used to compare the devices with transversal section area, lesions depth and between themselves. The area under ROC curve, sensitivity, specificity as well as accuracy were calculated and verified with McNemar test. Dd and RAUC showed statistically significant correlation with gold standard (p < 0.01 for Dd and p < 0.05 for RAUC) and between themselves (r = 0,83 in vivo and r = 0,87 in vitro). Although it was significant, the devices showed low correlation with depth of lesions in vivo and in vitro (r = ∼ 0.43). The transversal section area of the lesion had no influence on readings in both devices. Dd showed higher sensitivity (0.76) than PS (0.60) in vivo (p < 0.05), though this fact was not able to improve its performance. In turn, PS showed higher sensitivity (0.88) than Dd (0.79) in vitro, but this difference was not significantly. The other parameters did not show statistically significant differences (p < 0.05) between methods. PS showed positive correlation with Dd, equal correlation with lesions depth and higher ability of detecting the disease in vitro, what suggests that if accompanied with a conic and an angulated probe and a dedicated software, the PS method could be useful in clinics

  1. Quality control of baby food products on the basis of results obtained using the instrumental neutron-activation analysis technique

    International Nuclear Information System (INIS)

    Mukhammedov, S.; Khaydarov, A.; Pardaev, O.

    2013-01-01

    The purpose of this study was to use the instrumental neutron-activation analysis (INAA) to determine the elemental composition of some kind of imported baby food products (BFP) and to compare the results with the permissible contents. The nuclear reactor WWR-SM of INP has been used to develop INAA to study the mineral composition of some children's food products. The concentration of 26 trace elements, including Mg, Ca, Fe, Zn, etc. was found. The comparison of the results with regulation contents and the daily data on food needs have shown that the investigated group of BFP does not meet the requirements for all trace and macro elements composition. (authors)

  2. Pressure suppression system (PSS) for nuclear ships. Experimental results obtained at the GKSS PSS-test-facillity

    International Nuclear Information System (INIS)

    Aust, E.; Niemann, H.R.; Schwan, H.; Vollbrandt, J.

    1978-01-01

    The PSS-test facility is shortly presented which was designed to show experimentally the operation of the pressure suppression containment for the NCS 80 concept. The results of the experimental LOCA-simulation tests in the PSS-test facility are illustrated by diagrams. The observed phenomena as chugging and pessure oscillations immediately after vent clearing are reported as well as the thermohydraulic loadings of the total system. Finally a short view is given on the future test program

  3. Study of Finite Element Number Influence over the Obtained Results in Finite Element Analyses of a Mechanical Structure

    Directory of Open Access Journals (Sweden)

    Ana-Maria Budai

    2013-05-01

    Full Text Available This paper present the results of a study that was made to establish the influence of finite element number used to determined the real load of a structure. Actually, the study represent a linear static analyze for a link gear control mechanism of a Kaplan turbine. The all analyze was made for the normal condition of functioning having like final scope to determine de life time duration of mentioned mechanism.

  4. Constructing kinetics fatigue diagrams using testing results obtained on a machine with rigid loading for specimens of various thickness

    International Nuclear Information System (INIS)

    Simin'kovich, V.N.; Gladkij, Ya.N.; Deev, N.A.

    1981-01-01

    Bending tests of 40KhS steel specimens, tempered at 200 and 500 deg C, are conducted to investigate the possible effects of specimen thickness on fatigue crack growth. Kinetic fatigue diagrams are constructed using the investigation results. An increase in crack growth with thickness is observed only in high-tempered specimens. Changes in specimen thickness do not affect crack growth in 40KhS low-tempered steel [ru

  5. Characterization of High-Power Turbomachinery Tilting Pad Journal Bearings: First Results Obtained on a Novel Test Bench

    Directory of Open Access Journals (Sweden)

    Enrico Ciulli

    2018-01-01

    Full Text Available Tilting pad journal bearings are usually employed in turbomachines for their stable behavior at high rotational speeds. Devoted test rigs have been realized to validate the predictions of theoretical models. However, the design of new high-performance and large-size bearings needs to be supported by experimental investigations on high-performance large test rigs. The main characteristics of a recently built facility for testing large tilting pad journal bearings with diameters from 150 to 300 mm are described in this work. The test rig is versatile and can be used to test bearings of different size, configurations and to investigate the influence of many parameters, even the effect of misalignment. Sample results of the static characterization of a four-pad high-performance tilting pad journal bearing are reported evidencing some transient effects. A few sample dynamic results are also reported. The presented experimental results demonstrated the capabilities of the rig for investigating the static and the dynamic characteristics of the bearings accurately measuring slow and fast variables.

  6. Porous titanium obtained by a new powder metallurgy technique: Preliminary results of human osteoblast adhesion on surface polished substrates.

    Science.gov (United States)

    Biasotto, M; Ricceri, R; Scuor, N; Schmid, C; Sandrucci, M A; Di Lenarda, R; Matteazzi, P

    2003-01-01

    This study concerns a novel powder metallurgy method for producing porous titanium (pTi) exhibiting high mechanical properties. The preparation procedure consisted of the following stages: first, the preparation of Ti and titanium hydride (TiH2) powder mixtures and their consolidation with a cold isostatic press, followed by a sintering of the green bodies performed with hot isostatic press (HIP) equipment. Thermal decomposition in controlled environment of the TiH2 phase results in the foam structure. The resulting porosity percolates with a volume fraction of approximately 20%. The final material exhibits interesting mechanical properties, comparable to those of full density titanium (between grade 2 and grade 3), with the advantage of a minor density. The samples produced were tested to verify their biological response by studying the effectiveness of osteoblast adhesion and growth. In this preliminary study, osteoblastic cell morphology was investigated and compared to that observed on fully dense commercially pure titanium (Ti-cp) (ASTM, grade 3). The preliminary results were promising regarding cellular adhesion and spreading. (Journal of Applied Biomaterials & Biomechanics 2003; 1: 172-7).

  7. The majority of irregular menstrual cycles in adolescence are ovulatory: results of a prospective study.

    Science.gov (United States)

    Peña, Alexia S; Doherty, Dorota A; Atkinson, Helen C; Hickey, Martha; Norman, Robert J; Hart, Roger

    2018-03-01

    While ovulation is most likely to occur in adolescent girls with regular menstrual cycles, there are limited data on the incidence of ovulation in girls with irregular menstrual cycles in early postmenarcheal years. The aim of the study was to evaluate the presence of ovulation in healthy postmenarcheal girls with irregular menstrual cycles. Prospective cohort study over 12 weeks including 40 healthy postmenarcheal girls recruited from the population-based cohort of adolescents from Western Australian Pregnancy Cohort (Raine) Study with irregular menstrual cycles defined by either menstrual cycles 35 days in duration or cycle length that varied from month to month by >4 days according to menstrual diaries. Ovulation defined by urinary pregnanediol-3α-glucuronide/creatinine measurements higher than three times above minimum value obtained from 12 samples (1 per week). Forty girls (37 Caucasians) with irregular menstrual cycles aged 15.1 (median (IQR) 14.9-15.4) years who were 2.3 (1.9-3.3) years postmenarche were assessed. Urinary pregnanediol-3α-glucuronide/creatinine values identified that 33 girls (82.5%) ovulated during the 3 months of observation and 7 girls had anovulatory cycles. Menstrual diaries collected for a median (IQR) of 159 (137.5-188.2) days showed median minimal and maximum menstrual cycle duration of 24 (11.5-29) and 38.5 (35-48) days, respectively. A large proportion of healthy adolescent girls with irregular menstrual cycles are still ovulating despite irregular and infrequent menses. © Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2018. All rights reserved. No commercial use is permitted unless otherwise expressly granted.

  8. High resolution spectrometry: how the analyzer and spectrometer performances and the beam emittance contribute to the results obtained

    International Nuclear Information System (INIS)

    Roussel, P.

    1984-01-01

    Using first order calculations derived for an achromatic system A) (deltaxsub(F)/deltaEsub(i)=0) or an optimised system O) (xsub(F) minima). It is shown that the final resolution measured in the local plane of the spectrometer depends only on the emittance of the accelerator and of the efficient area of the analyser exclusive of the properties of the spectrometer. The use of this result is only limited by higher order terms in the calculation or considerations out of this scope like target effects etc.. [fr

  9. Thermal monitoring of hydrothermal activity by permanent infrared automatic stations: Results obtained at Solfatara di Pozzuoli, Campi Flegrei (Italy)

    Science.gov (United States)

    Chiodini, G.; Vilardo, G.; Augusti, V.; Granieri, D.; Caliro, S.; Minopoli, C.; Terranova, C.

    2007-12-01

    A permanent automatic infrared (IR) station was installed at Solfatara crater, the most active zone of Campi Flegrei caldera. After a positive in situ calibration of the IR camera, we analyze 2175 thermal IR images of the same scene from 2004 to 2007. The scene includes a portion of the steam heated hot soils of Solfatara. The experiment was initiated to detect and quantify temperature changes of the shallow thermal structure of a quiescent volcano such as Solfatara over long periods. Ambient temperature is the main parameter affecting IR temperatures, while air humidity and rain control image quality. A geometric correction of the images was necessary to remove the effects of slow movement of the camera. After a suitable correction the images give a reliable and detailed picture of the temperature changes, over the period October 2004 to January 2007, which suggests that origin of the changes were linked to anthropogenic activity, vegetation growth, and the increase of the flux of hydrothermal fluids in the area of the hottest fumaroles. Two positive temperature anomalies were registered after the occurrence of two seismic swarms which affected the hydrothermal system of Solfatara in October 2005 and October 2006. It is worth noting that these signs were detected in a system characterized by a low level of activity with respect to systems affected by real volcanic crisis where more spectacular results will be expected. Results of the experiment show that this kind of monitoring system can be a suitable tool for volcanic surveillance.

  10. Development of the safety evaluation system in the respects of organizational factors and workers' consciousness. Pt. 1. Study of validities of functions for necessary evaluation and results obtained

    International Nuclear Information System (INIS)

    Takano, Kenichi; Tsuge, Tadafumi; Hasegawa, Naoko; Hirose, Ayako; Sasou, Kunihide

    2002-01-01

    CRIEPI decided to develop the safety evaluation system to investigate the safety level of the industrial sites due to questionnaires of organizational climate, safety managements, and workers' safety consciousness to workers. This report describes the questionnaire survey to apply to the domestic nuclear power plant for using obtained results as a fundamental data in order to construct the safety evaluation system. This system will be used for promoting safety culture in organizations of nuclear power plants. The questionnaire survey was conducted to 14 nuclear power stations for understanding the present status relating to safety issues. This questionnaire involves 122 items classified into following three categories: (1) safety awareness and behavior of plant personnel; (2) safety management; (3) organizational climate, based on the model considering contributing factor groups to safety culture. Obtained results were analyzed by statistical method to prepare functions of evaluation. Additionally, by applying a multivariate analysis, it was possible to extract several crucial factors influencing safety performance and to find a comprehensive safety indicator representing total organizational safety level. Significant relations were identified between accident rates (both labor accidents and facility failures) and above comprehensive safety indicator. Next, 122 questionnaire items were classified into 20 major safety factors to grasp the safety profiles of each site. This profile is considered as indicating the features of each site and also indicating the direction of progress for improvement of safety situation in the site. These findings can be reflected in developing the safety evaluation system, by confirming the validity of the evaluation method and giving specific functions. (author)

  11. Overview of experimental results obtained under the Prestressed Concrete Nuclear Pressure Vessel Development Program at the Oak Ridge National Laboratory

    International Nuclear Information System (INIS)

    Naus, D.J.

    1978-01-01

    Under the Prestressed Concrete Nuclear Pressure Vessel Development Program at the Oak Ridge National Laboratory, various aspects of Prestressed Concrete Pressure Vessels (PCPVs) are investigated and evaluated with respect to reliability, structural performance, constructability, and economy. Based upon identified needs, analytical and experimental investigations are conducted. Areas of interest include finite-element analysis development, materials and structural behavior tests, instrumentation evaluation and development, and structural model tests. Studies have been recently completed in the following areas: concrete embedment instrumentation systems for PCPVs, grouted-nongrouted prestressing systems, acoustic emission as a technique for structural integrity monitoring, and model tests of steam-generator cavity closure plugs for a Gas-Cooled Fast Reactor (GCFR). An overview of results is presented

  12. Wear of control rod cluster assemblies and of instrumentation thimbles: first results obtained with the vibrateau wear simulator

    International Nuclear Information System (INIS)

    Zbinden, M.; Hersant, D.

    1993-07-01

    Several REP components are affected by a particular sort of damage called impact/sliding wear. This kind of wear, originating from flow induced vibrations, affects loosely supported tubular structures. The main involved components are: - the RCCAs claddings and the guides tubes, - the instrumentation thimbles, - the fuel rods claddings, - the SG tubes. The R and D Division is concerned with studies aiming to understand and to master the phenomena leading to this wear. The MTC Branch is charged of the study of the wear itself. Tests are carried out on wear rigs to understand and to model wear mechanisms. The following work is related to the two first wear tests campaigns on the VIBRATEAU wear simulator: - a reproducibility test series in order to assess the spreading of the experimental results, - a comparative test series on surface treatments used to improve the components war resistance. (authors). 7 figs., 2 tabs., 4 refs

  13. Short Communication: Testosterone Measured with an Automatic Immunoassay Compares Reasonbly Well to Results Obtained by LC-MS/MS

    DEFF Research Database (Denmark)

    Knudsen, Cindy Søndersø; Højskov, Carsten Schriver; Møller, Holger Jon

    2016-01-01

    Background: Previous studies have reported problems measuring testosterone with immunological assays. Here we explore an automatic second generation immunoassay compared to a LC-MS/MS method. Methods: We collected blood samples from 76 women and measured testosterone, progesterone, gender...... hormonebinding globulin (SHBG), and albumin employing Cobas e601/c501. Testosterone, androstenedione (andro), dehydroepiandrosterone sulphate (DHEAS), and 17-hydroxyprogesterone (17-OHP) concentrations were measured employing LC-MS/MS. We evaluated the difference between testosterone measured by the two methods...... and examined the potential interference from the selected steroids and bindings proteins. Results: Testosterone concentrations measured by the two methods yielded: Cobas e601 = 1.240 x (LC-MS/MS) - 0.197, r = 0.84, for testosterone concentrations between 0.22 - 4.9 nmol/L. A positive correlation was observed...

  14. First results of registering ionospheric disturbances obtained with SibNet network of GNSS receivers in active space experiments

    Science.gov (United States)

    Ishin, Artem; Perevalova, Natalia; Voeykov, Sergey; Khakhinov, Vitaliy

    2017-12-01

    Global and regional networks of GNSS receivers have been successfully used for geophysical research for many years; the number of continuous GNSS stations in the world is steadily growing. The article presents the first results of the use of a new regional network of GNSS stations (SibNet) in active space experiments. The Institute of Solar-Terrestrial Physics of Siberian Branch of Russian Academy of Sciences (ISTP SB RAS) has established this network in the South Baikal region. We describe in detail SibNet, characteristics of receivers in use, parameters of antennas and methods of their installation. We also present the general structure of observation site and the plot of coverage of the receiver operating zone at 50-55° latitudes by radio paths. It is shown that the selected location of receivers allows us to detect ionospheric irregularities of various scales. The purpose of the active space experiments was to reveal and record parameters of the ionospheric irregu larities caused by effects from jet streams of Progress cargo spacecraft. The mapping technique enabled us to identify weak, vertically localized ionospheric irregularities and associate them with the Progress spacecraft engine impact. Thus, it has been shown that SibNet deployed in the Southern Baikal region is an effective instrument for monitoring ionospheric conditions.

  15. Plutonium burning and minor actinides transmutation in fast reactors: first results obtained within the frame of the CAPRA programme

    International Nuclear Information System (INIS)

    Garnier, J.C.; Rouault, J.; Kiefhaber, E.; Sunderland, R.

    1994-01-01

    The CAPRA program gas been established by the CEA in early 1993 with the primary goal of investigating the feasibility of a fast reactor core optimised to burn plutonium. CAPRA is now being jointly pursued by the European Research and Development (R and D) organisations (CEA in France, AEA in the UK and KFK in Germany) and the design companies grouped under the European Fast Reactor Associates umbrella. The first phase of the CAPRA programme is planned to last until the end of 1994. Its goal is to deliver an overall assessment on the feasibility of fast reactor plutonium burner cores. This assessment will also include the minor actinides transmutation capability of such cores. The objective of this paper is to present the progress made so far. After an introduction to the basic physics boundary conditions of burner cores, a description of the studies performed and the main results are given. Then the efforts made towards the definition of an accompanying experimental Research and Development (R and D) program are summarised, followed by the conclusions and an outlook to the future work. (authors). 4 refs., 3 figs., 2 tabs

  16. Major Results of the OECD BEMUSE (Best Estimate Methods; Uncertainty and Sensitivity Evaluation) Programme

    International Nuclear Information System (INIS)

    Reventos, F.

    2008-01-01

    One of the goals of computer code models of Nuclear Power Plants (NPP) is to demonstrate that these are designed to respond safely at postulated accidents. Models and codes are an approximation of the real physical behaviour occurring during a hypothetical transient and the data used to build these models are also known with certain accuracy. Therefore code predictions are uncertain. The BEMUSE programme is focussed on the application of uncertainty methodologies to large break LOCAs. The programme intends to evaluate the practicability, quality and reliability of best-estimate methods including uncertainty evaluations in applications relevant to nuclear reactor safety, to develop common understanding and to promote/facilitate their use by the regulator bodies and the industry. In order to fulfil its objectives BEMUSE is organized in to steps and six phases. The first step is devoted to the complete analysis of a LB-LOCA (L2-5) in an experimental facility (LOFT) while the second step refers to an actual Nuclear Power Plant. Both steps provide results on thermalhydraulic Best Estimate simulation as well as Uncertainty and sensitivity evaluation. At the time this paper is prepared, phases I, II and III are fully completed and the corresponding reports have been issued. Phase IV draft report is by now being reviewed while participants are working on Phase V developments. Phase VI consists in preparing the final status report which will summarizes the most relevant results of the whole programme.

  17. Status of data, major results, and plans for geophysical activities, Yucca Mountain Project

    Energy Technology Data Exchange (ETDEWEB)

    Oliver, H.W. [Geological Survey, Menlo Park, CA (USA); Hardin, E.L. [Science Applications International Corp., Las Vegas, NV (USA); Nelson, P.H. [Geological Survey, Denver, CO (USA)] [eds.

    1990-07-01

    This report describes past and planned geophysical activities associated with the Yucca Mountain Project and is intended to serve as a starting point for integration of geophysical activities. This report relates past results to site characterization plans, as presented in the Yucca Mountain Site Characterization Plan (SCP). This report discusses seismic exploration, potential field methods, geoelectrical methods, teleseismic data collection and velocity structural modeling, and remote sensing. This report discusses surface-based, airborne, borehole, surface-to-borehole, crosshole, and Exploratory Shaft Facility-related activities. The data described in this paper, and the publications discussed, have been selected based on several considerations; location with respect to Yucca Mountain, whether the success or failure of geophysical data is important to future activities, elucidation of features of interest, and judgment as to the likelihood that the method will produce information that is important for site characterization. 65 refs., 19 figs., 12 tabs.

  18. Status of data, major results, and plans for geophysical activities, Yucca Mountain Project

    International Nuclear Information System (INIS)

    Oliver, H.W.; Hardin, E.L.; Nelson, P.H.

    1990-07-01

    This report describes past and planned geophysical activities associated with the Yucca Mountain Project and is intended to serve as a starting point for integration of geophysical activities. This report relates past results to site characterization plans, as presented in the Yucca Mountain Site Characterization Plan (SCP). This report discusses seismic exploration, potential field methods, geoelectrical methods, teleseismic data collection and velocity structural modeling, and remote sensing. This report discusses surface-based, airborne, borehole, surface-to-borehole, crosshole, and Exploratory Shaft Facility-related activities. The data described in this paper, and the publications discussed, have been selected based on several considerations; location with respect to Yucca Mountain, whether the success or failure of geophysical data is important to future activities, elucidation of features of interest, and judgment as to the likelihood that the method will produce information that is important for site characterization. 65 refs., 19 figs., 12 tabs

  19. KRAS mutation testing in colorectal cancer: comparison of the results obtained using 3 different methods for the analysis of codons G12 and G13.

    Science.gov (United States)

    Bihl, Michel P; Hoeller, Sylvia; Andreozzi, Maria Carla; Foerster, Anja; Rufle, Alexander; Tornillo, Luigi; Terracciano, Luigi

    2012-03-01

    Targeting the epidermal growth factor receptor (EGFR) is a new therapeutic option for patients with metastatic colorectal or lung carcinoma. However, the therapy efficiency highly depends on the KRAS mutation status in the given tumour. Therefore a reliable and secure KRAS mutation testing is crucial. Here we investigated 100 colorectal carcinoma samples with known KRAS mutation status (62 mutated cases and 38 wild type cases) in a comparative manner with three different KRAS mutation testing techniques (Pyrosequencing, Dideoxysequencing and INFINITI) in order to test their reliability and sensitivity. For the large majority of samples (96/100, 96%), the KRAS mutation status obtained by all three methods was the same. Only two cases with clear discrepancies were observed. One case was reported as wild type by the INFINITI method while the two other methods detected a G13C mutation. In the second case the mutation could be detected by the Pyrosequencing and INFINITI method (15% and 15%), while no signal for mutation could be observed with the Dideoxysequencing method. Additional two unclear results were due to a detection of a G12V with the INFINITI method, which was below cut-off when repeated and which was not detectable by the other two methods and very weak signals in a G12V mutated case with the Dideoxy- and Pyroseqencing method compared to the INFINITI method, respectively. In summary all three methods are reliable and robust methods in detecting KRAS mutations. INFINITI, however seems to be slightly more sensitive compared to Dideoxy- and Pyrosequencing.

  20. Fetal Environment Is a Major Determinant of the Neonatal Blood Thyroxine Level: Results of a Large Dutch Twin Study.

    Science.gov (United States)

    Zwaveling-Soonawala, Nitash; van Beijsterveldt, Catharina E M; Mesfum, Ertirea T; Wiedijk, Brenda; Oomen, Petra; Finken, Martijn J J; Boomsma, Dorret I; van Trotsenburg, A S Paul

    2015-06-01

    The interindividual variability in thyroid hormone function parameters is much larger than the intraindividual variability, suggesting an individual set point for these parameters. There is evidence to suggest that environmental factors are more important than genetic factors in the determination of this individual set point. This study aimed to quantify the effect of genetic factors and (fetal) environment on the early postnatal blood T4 concentration. This was a classical twin study comparing the resemblance of neonatal screening blood T4 concentrations in 1264 mono- and 2566 dizygotic twin pairs retrieved from the population-based Netherlands Twin Register. Maximum-likelihood estimates of variance explained by genetic and environmental influences were obtained by structural equation modeling in data from full-term and preterm twin pairs. In full-term infants, genetic factors explained 40%/31% of the variance in standardized T4 scores in boys/girls, and shared environment, 27%/22%. The remaining variance of 33%/47% was due to environmental factors not shared by twins. For preterm infants, genetic factors explained 34%/0% of the variance in boys/girls, shared environment 31%/57%, and unique environment 35%/43%. In very preterm twins, no significant contribution of genetic factors was observed. Environment explains a large proportion of the resemblance of the postnatal blood T4 concentration in twin pairs. Because we analyzed neonatal screening results, the fetal environment is the most likely candidate for these environmental influences. Genetic influences on the T4 set point diminished with declining gestational age, especially in girls. This may be due to major environmental influences such as immaturity and nonthyroidal illness in very preterm infants.

  1. Clinical results of a surgical technique using endobuttons for complete tendon tear of pectoralis major muscle: report of five cases

    Directory of Open Access Journals (Sweden)

    Uchiyama Yoshiyasu

    2011-09-01

    Full Text Available Abstract Background We herein describe a surgical technique for the repair of complete tear of the pectoralis major (PM tendon using endobuttons to strengthen initial fixation. Methods Five male patients (3 judo players, 1 martial arts player, and 1 body builder were treated within 2 weeks of sustaining complete tear of the PM tendon. Average age at surgery and follow-up period were 28.4 years (range, 23-33 and 28.8 months (range, 24-36. A rectangular bone trough (about 1 × 4 cm was created on the humerus at the insertion of the distal PM tendon. The tendon stump was introduced into this trough, and fixed to the reverse side of the humeral cortex using endobuttons and non-absorbable suture. Clinical assessment of re-tear was examined by MRI. Shoulder range of motion (ROM, outcome of treatment, and isometric power were measured at final follow-up. Results There were no clinical re-tears, and MRI findings also showed continuity of the PM tendon in all cases at final follow-up. Average ROM did not differ significantly between the affected and unaffected shoulders. The clinical outcomes at final follow-up were excellent (4/5 cases or good (1/5. In addition, postoperative isometric power in horizontal flexion of the affected shoulder showed complete recovery when compared with the unaffected side. Conclusions Satisfactory outcomes could be obtained when surgery using the endobutton technique was performed within 2 weeks after complete tear of the PM tendon. Therefore, our new technique appears promising as a useful method to treat complete tear of the PM tendon.

  2. Residential Proximity to Major Roadways Is Not Associated with Cardiac Function in African Americans: Results from the Jackson Heart Study

    Directory of Open Access Journals (Sweden)

    Anne M. Weaver

    2016-06-01

    Full Text Available Cardiovascular disease (CVD, including heart failure, is a major cause of morbidity and mortality, particularly among African Americans. Exposure to ambient air pollution, such as that produced by vehicular traffic, is believed to be associated with heart failure, possibly by impairing cardiac function. We evaluated the cross-sectional association between residential proximity to major roads, a marker of long-term exposure to traffic-related pollution, and echocardiographic indicators of left and pulmonary vascular function in African Americans enrolled in the Jackson Heart Study (JHS: left ventricular ejection fraction, E-wave velocity, isovolumic relaxation time, left atrial diameter index, and pulmonary artery systolic pressure. We examined these associations using multivariable linear or logistic regression, adjusting for potential confounders. Of 4866 participants at study enrollment, 106 lived <150 m, 159 lived 150–299 m, 1161 lived 300–999 m, and 3440 lived ≥1000 m from a major roadway. We did not observe any associations between residential distance to major roads and these markers of cardiac function. Results were similar with additional adjustment for diabetes and hypertension, when considering varying definitions of major roadways, or when limiting analyses to those free from cardiovascular disease at baseline. Overall, we observed little evidence that residential proximity to major roads was associated with cardiac function among African Americans.

  3. Identification of hazelnut major allergens in sensitive patients with positive double-blind, placebo-controlled food challenge results

    DEFF Research Database (Denmark)

    Pastorello, Elide A; Vieths, Stefan; Pravettoni, Valerio

    2002-01-01

    The hazelnut major allergens identified to date are an 18-kd protein homologous to Bet v 1 and a 14-kd allergen homologous to Bet v 2. No studies have reported hazelnut allergens recognized in patients with positive double-blind, placebo-controlled food challenge (DBPCFC) results or in patients...

  4. Evaluation of instrumental parameters for obtaining acceptable analytical results of the Dosimetry Laboratory of Chemistry of the Regional Center of Nuclear Sciences, CNEN-NE, Recife, Brazil

    International Nuclear Information System (INIS)

    Souza, V.L.B.; Figueiredo, M.D.C.; Cunha, M.S.

    2008-01-01

    Instrumental parameters need to be evaluated for obtaining acceptable analytical results for a specific instrument. The performance of the UV-VIS spectrophotometer can be verified for wavelengths and absorbances with appropriate materials (solutions of different concentrations of K 2 CrO 4 , for example). The aim of this work was to demonstrate the results of the procedures to control the quality of the measurements carried out in the laboratory in the last four years. The samples were analyzed in the spectrophotometer and control graphics were obtained for K 2 CrO 4 and Fe 3+ absorbance values. The variation in the results obtained for the stability of the spectrophotometer and for the control of its calibration did not exceed 2%. (author)

  5. Review of the scientific results obtained at the research reactor-booster IBR-30 and the Program of investigations at the neutron source IREN

    CERN Document Server

    Furman, W

    2002-01-01

    Brief review of the main scientific results obtained at research reactor booster IBR-30 and its predecessor IBR and IBR-1 for the period 1960 - 2001 is presented. The thesis of the scientific program for the upgrade of IBR-30 resonance neutron source IREN are adduced

  6. Aircraft and ground vehicle friction correlation test results obtained under winter runway conditions during joint FAA/NASA Runway Friction Program

    Science.gov (United States)

    Yager, Thomas J.; Vogler, William A.; Baldasare, Paul

    1988-01-01

    Aircraft and ground vehicle friction data collected during the Joint FAA/NASA Runway Friction Program under winter runway conditions are discussed and test results are summarized. The relationship between the different ground vehicle friction measurements obtained on compacted snow- and ice-covered conditions is defined together with the correlation to aircraft tire friction performance under similar runway conditions.

  7. Most recent developments in combined radium and high voltage therapy of uterine tumours as shown by the results obtained at the municipal hospital Passau

    International Nuclear Information System (INIS)

    Moos, G.

    1987-01-01

    It was the aim of the study described here to review data on healing successes achieved in malignant changes of the uterus. The results obtained were analysed on the bais of tumour stage and, in particular, the radiation dose actually administered. It could be shown that the treatment results currently achieved at this clinic are in keeping with relevant patient data collected previously or by other centres. (orig./MG) [de

  8. Structured health care for subjects with diabetic foot ulcers results in a reduction of major amputation rates

    Science.gov (United States)

    2013-01-01

    Objective We tested the effects of structured health care for the diabetic foot in one region in Germany aiming to reduce the number of major amputations. Research design and methods In a prospective study we investigated patients with diabetic foot in a structured system of outpatient, in-patient and rehabilitative treatment. Subjects were recruited between January 1st, 2000 and December 31, 2007. All participants underwent a two-year follow-up. The modified University of Texas Wound Classification System (UT) was the basis for documentation and data analysis. We evaluated numbers of major amputations, rates of ulcer healing and mortality. In order to compare the effect of the structured health care program with usual care in patients with diabetic foot we evaluated the same parameters at another regional hospital without interdisciplinary care of diabetic foot (controls). Results 684 patients with diabetic foot and 508 controls were investigated. At discharge from hospital 28.3% (structured health care program, SHC) vs. 23.0% (controls) of all ulcers had healed completely. 51.5% (SHC) vs. 49.8% (controls) were in UT grade 1. Major amputations were performed in 32 subjects of the structured health care program group (4.7%) vs. 110 (21.7%) in controls (p<0.0001). Mortality during hospitalization was 2.5% (SHC) vs. 9.4% in controls (p<0.001). Conclusions With the structured health care program we achieved a significant reduction of major amputation rates by more than 75% as compared to standard care. PMID:23497152

  9. Interobserver agreement of the injury diagnoses obtained by postmortem computed tomography of traffic fatality victims and a comparison with autopsy results

    DEFF Research Database (Denmark)

    Leth, Peter Mygind; Struckmann, Henrik; Lauritsen, Jens

    2013-01-01

    The present study investigated the interobserver variation between a radiologist and a forensic pathologist in 994 injury diagnoses obtained by postmortem computed tomography (CT) of 67 traffic fatality victims, and the results were compared with diagnoses obtained by autopsy. The injuries were...... system, but the pathologist diagnosed more organ injuries. We recommend the use of a radiologist as a consultant for the evaluation of postmortem CT images. Training in radiology should be included in forensic medicine postgraduate training. CT was superior to autopsy in detecting abnormal air...

  10. Major results from safety-related integral effect tests with VISTA-ITL for the SMART design

    International Nuclear Information System (INIS)

    Park, H. S.; Min, B. Y.; Shin, Y. C.; Yi, S. J.

    2012-01-01

    A series of integral effect tests (IETs) was performed by the Korea Atomic Energy Research Inst. (KAERI) using the VISTA integral test loop (VISTA-ITL) as a small-scale IET program. Among them this paper presents major results acquired from the safety-related IETs with the VISTA-ITL facility for the SMART design. Three small-break loss-of-coolant accident (SBLOCA) tests of safety injection system (SIS) line break, shutdown cooling system (SCS) line break and pressurizer safety valve (PSV) line break were successfully performed and the transient characteristics of a complete loss of flowrate (CLOF) was simulated properly with the VISTA-ITL facility. (authors)

  11. Comparative analysis of the results obtained by computer code ASTEC V2 and RELAP 5.3.2 for small leak ID 80 for VVER 1000

    International Nuclear Information System (INIS)

    Atanasova, B.; Grudev, P.

    2011-01-01

    The purpose of this report is to present the results obtained by simulation and subsequent analysis of emergency mode for small leak with ID 80 for WWER 1000/B320 - Kozloduy NPP Units 5 and 6. Calculations were performed with the ASTEC v2 computer code used for calculation of severe accident, which was designed by French and German groups - IRSN and GRS. Integral RELAP5 computer code is used as a reference for comparison of results. The analyzes are focused on the processes occurring in reactor internals phase of emergency mode with significant core damage. The main thermohydraulic parameters, start of reactor core degradation and subsequent fuel relocalization till reactor vessel failure are evaluated in the analysis. RELAP5 computer code is used as a reference code to compare the results obtained till early core degradation that occurs after core stripping and excising of fuel temperature above 1200 0 C

  12. Fermentation Results and Chemical Composition of Agricultural Distillates Obtained from Rye and Barley Grains and the Corresponding Malts as a Source of Amylolytic Enzymes and Starch.

    Science.gov (United States)

    Balcerek, Maria; Pielech-Przybylska, Katarzyna; Dziekońska-Kubczak, Urszula; Patelski, Piotr; Strąk, Ewelina

    2016-10-01

    The objective of this study was to determine the efficiency of rye and barley starch hydrolysis in mashing processes using cereal malts as a source of amylolytic enzymes and starch, and to establish the volatile profile of the obtained agricultural distillates. In addition, the effects of the pretreatment method of unmalted cereal grains on the physicochemical composition of the prepared mashes, fermentation results, and the composition of the obtained distillates were investigated. The raw materials used were unmalted rye and barley grains, as well as the corresponding malts. All experiments were first performed on a semi-technical scale, and then verified under industrial conditions in a Polish distillery. The fermentable sugars present in sweet mashes mostly consisted of maltose, followed by glucose and maltotriose. Pressure-thermal treatment of unmalted cereals, and especially rye grains, resulted in higher ethanol content in mashes in comparison with samples subjected to pressureless liberation of starch. All agricultural distillates originating from mashes containing rye and barley grains and the corresponding malts were characterized by low concentrations of undesirable compounds, such as acetaldehyde and methanol. The distillates obtained under industrial conditions contained lower concentrations of higher alcohols (apart from 1-propanol) than those obtained on a semi-technical scale.

  13. Fermentation Results and Chemical Composition of Agricultural Distillates Obtained from Rye and Barley Grains and the Corresponding Malts as a Source of Amylolytic Enzymes and Starch

    Directory of Open Access Journals (Sweden)

    Maria Balcerek

    2016-10-01

    Full Text Available The objective of this study was to determine the efficiency of rye and barley starch hydrolysis in mashing processes using cereal malts as a source of amylolytic enzymes and starch, and to establish the volatile profile of the obtained agricultural distillates. In addition, the effects of the pretreatment method of unmalted cereal grains on the physicochemical composition of the prepared mashes, fermentation results, and the composition of the obtained distillates were investigated. The raw materials used were unmalted rye and barley grains, as well as the corresponding malts. All experiments were first performed on a semi-technical scale, and then verified under industrial conditions in a Polish distillery. The fermentable sugars present in sweet mashes mostly consisted of maltose, followed by glucose and maltotriose. Pressure-thermal treatment of unmalted cereals, and especially rye grains, resulted in higher ethanol content in mashes in comparison with samples subjected to pressureless liberation of starch. All agricultural distillates originating from mashes containing rye and barley grains and the corresponding malts were characterized by low concentrations of undesirable compounds, such as acetaldehyde and methanol. The distillates obtained under industrial conditions contained lower concentrations of higher alcohols (apart from 1-propanol than those obtained on a semi-technical scale.

  14. LEP and results obtained by DELPHI after four years of operation; LEP i wyniki uzyskane przez DELPHI po czterech latach dzialania

    Energy Technology Data Exchange (ETDEWEB)

    Blocki, J. [Warsaw Univ. (Poland). Inst. Fizyki Doswiadczalnej; Brueckman de Renstrom, P.; Budziak, A. [Institute of Nuclear Physics, Cracow (Poland)] [and others

    1993-10-01

    We characterize the most important problems of modern elementary particles physics, for the solution of which the LEP (Large Electron Positron) accelerator was built. We present the characteristics of this accelerator. The structure and properties of the DELPHI detector are described with special emphasis on the contribution of Polish groups. The most important results obtained so far in the LEP accelerator are discussed. (author). 12 refs, 17 figs, 1 tab.

  15. Carbon and nitrogen determination in Zr by photon or proton activation analysis. Comparison between the results obtained by this method and other analytical techniques

    International Nuclear Information System (INIS)

    Petit, J.; Gosset, J.; Engelmann, C.

    1977-01-01

    Carbon and nitrogen are determined by the following nuclear reactions: 12 C(γ,n) 11 C and 14 N(p,α) 11 C. The performances of the method and the main interferences are considered. The process developed for the separation of carbon-11 from zirconium is described and its efficiency evaluated. The results obtained are compared with those given by different laboratories using various analytical techniques [fr

  16. Major Results from 1-Train Passive Safety System Tests for the SMART Design with the SMART-ITL Facility

    Energy Technology Data Exchange (ETDEWEB)

    Park, Hyun-Sik; Bae, Hwang; Ryu, Sung-Uk; Jeon, Byong-Guk; Ruy, Hyobong; Kim, Woo-Shik; Byun, Sun-Joon; Shin, Yong-Cheol; Min, Kyoung-Ho; Yi, Sung-Jae [KAERI, Daejeon (Korea, Republic of)

    2015-05-15

    To satisfy the domestic and international needs for nuclear safety improvement after the Fukushima accident, an effort to improve its safety has been studied, and a Passive Safety System (PSS) for SMART has been designed. In addition, an Integral Test Loop for the SMART design (SMART-ITL, or FESTA) has been constructed and it finished its commissioning tests in 2012. Consequently, a set of Design Base Accident (DBA) scenarios have been simulated using SMARTITL. Recently, a test program to validate the performance of the SMART PSS was launched and its scaled-down test facility was additionally installed at the existing SMART-ITL facility. In this paper, the major results from the 1-train passive safety system validation tests with the SMARTITL facility will be summarized. The acquired data will be used to validate the safety analysis code and its related models, to evaluate the performance of SMART PSS, and to provide base data during the application phase of the SDA revision and construction licensing. In this paper, the major results from the validation tests of the SMART passive safety system using a 1-train test facility were summarized. They include a dozen of SMART PSS tests using 1-train SMART PSS tests. From the test results, it was estimated that the SMART PSS has sufficient cooling capability to deal with the SBLOCA scenario of SMART. During the SBLOCA scenario, in the CMT, the water layer inventory was well stratified thermally and the safety injection water was injected efficiently into the RPV from the initial period, and cools down the RCS properly.

  17. Who is responsible for the team’s results? Media framing of sports actors’ responsibility in major sports competitions

    Directory of Open Access Journals (Sweden)

    Diana Luiza Dumitriu

    2016-05-01

    Full Text Available Media are no longer just a witness to sports events, facilitating our access to them, but have become the most powerful judging platform for sports competitions, serving as a guide for their interpretation and evaluation. The present study focuses on media framing of sports actors’ responsibility when it comes to major sports competitions. Who is responsible for the team’s performance and results? In analysing media discourse, framing effects of sports events coverage will be examined from two inter-correlated dimensions, textually and visually. Based on an event-related corpus of on-line press articles from four national newspapers, this case study covers two major sports events: 2010 European Women’s Handball Championship and 2011 World Women’s Handball Championship. The discursive analysis of the press articles shows that, if winning competitive settings favour the emergence of a personification effect, building up sports heroes on both textual and visual dimensions, the responsibility of failure is rather diffused towards a collective referent. However, the visual component of press articles, along with the indirect strategy of addressing the responsibility issue throughout reported speech techniques, works as an alternative to the personification effect.

  18. Religious versus Conventional Psychotherapy for Major Depression in Patients with Chronic Medical Illness: Rationale, Methods, and Preliminary Results

    Directory of Open Access Journals (Sweden)

    Harold G. Koenig

    2012-01-01

    Full Text Available This paper (1 reviews the physical and religious barriers to CBT that disabled medically ill-depressed patients face, (2 discusses research on the relationship between religion and depression-induced physiological changes, (3 describes an ongoing randomized clinical trial of religious versus secular CBT in chronically ill patients with mild-to-moderate major depression designed to (a overcome physical and religious barriers to CBT and (b compare the efficacy of religious versus secular CBT in relieving depression and improving immune and endocrine functions, and (4 presents preliminary results that illustrate the technical difficulties that have been encountered in implementing this trial. CBT is being delivered remotely via instant messaging, telephone, or Skype, and Christian, Jewish, Muslim, Buddhist, and Hindu versions of religious CBT are being developed. The preliminary results described here are particular to the technologies employed in this study and are not results from the CBT clinical trial whose findings will be published in the future after the study ends and data are analyzed. The ultimate goal is to determine if a psychotherapy delivered remotely that integrates patients’ religious resources improves depression more quickly than a therapy that ignores them, and whether religious CBT is more effective than conventional CBT in reversing depression-induced physiological changes.

  19. Comparison between two sampling methods by results obtained using petrographic techniques, specially developed for minerals of the Itataia uranium phosphate deposit, Ceara, Brazil

    International Nuclear Information System (INIS)

    Salas, H.T.; Murta, R.L.L.

    1985-01-01

    The results of comparison of two sampling methods applied to a gallery of the uranium-phosphate ore body of Itataia-Ceara State, Brazil, along 235 metres of mineralized zone, are presented. The results were obtained through petrographic techniques especially developed and applied to both samplings. In the first one it was studied hand samples from a systematically sampling made at intervals of 2 metres. After that, the estimated mineralogical composition studies were carried out. Some petrogenetic observations were for the first time verified. The second sampling was made at intervals of 20 metres and 570 tons of ore extracted and distributed in sections and a sample representing each section was studied after crushing at -65. Their mineralogy were quantified and the degree of liberation of apatite calculated. Based on the mineralogical data obtained it was possible to represent both samplings and to make the comparison of the main mineralogical groups (phosphates, carbonates and silicates). In spite of utilizing different methods and methodology and the kind of mineralization, stockwork, being quite irregular, the results were satisfactory. (Author) [pt

  20. Surgical Correction of Posttraumatic Scapulothoracic Bursitis, Rhomboid Major Muscle Injury, Ipsilateral Glenohumeral Instability, and Headaches Resulting from Circus Acrobatic Maneuvers

    Directory of Open Access Journals (Sweden)

    John G. Skedros

    2015-01-01

    Full Text Available We report the case of a 28-year-old transgender (male-to-female patient that had a partial tear of the rhomboid major tendon, scapulothoracic bursitis, and glenohumeral instability on the same side. These conditions resulted from traumatic events during circus acrobatic maneuvers. Additional aspects of this case that make it unique include (1 the main traumatic event occurred during a flagpole exercise, where the patient’s trunk was suspended horizontally while a vertical pole was grasped with both hands, (2 headaches were associated with the periscapular injury and they improved after scapulothoracic bursectomy and rhomboid tendon repair, (3 surgical correction was done during the same operation with an open anterior capsular-labral reconstruction, open scapulothoracic bursectomy without bone resection, and rhomboid tendon repair, (4 a postoperative complication of tearing of the serratus anterior and rhomboid muscle attachments with recurrent scapulothoracic pain occurred from patient noncompliance, and (5 the postoperative complication was surgically corrected and ultimately resulted in an excellent outcome at the one-year final follow-up.

  1. Warm magnetic measurements of MCBCs: comparison between the results obtained with the Quadrupole Industrial Magnetic Measurement and the Corrector Industrial Magnetic Measurement systems

    CERN Document Server

    Remondino, Vittorio; Catalan-Lasheras, N

    2005-01-01

    MCBCs modules are first magnetically measured at Tesla using a second-generation Corrector Industrial Magnetic Measurement (CIMM). After assembly into the SSS quadrupoles, measurements are repeated at CERN using the Quadrupole Industrial Magnetic Measurement (QIMM) system. In this note, we compare the measurements provided by the two systems. In all the 18 cases examined, the correlation found is excellent. The consistency of the results obtained indicates that both systems are effective, that modules are correctly measured by the firm personnel and that magnetic characteristics of the modules do not change during their assembly in cold masses.

  2. Comparison of visual field test results obtained through Humphrey matrix frequency doubling technology perimetry versus standard automated perimetry in healthy children

    Directory of Open Access Journals (Sweden)

    Sibel Kocabeyoglu

    2013-01-01

    Full Text Available Aims : The aim of this study was to compare the visual field test results in healthy children obtained via the Humphrey matrix 24-2 threshold program and standard automated perimetry (SAP using the Swedish interactive threshold algorithm (SITA-Standard 24-2 test. Materials and Methods: This prospective study included 55 healthy children without ocular or systemic disorders who underwent both SAP and frequency doubling technology (FDT perimetry visual field testing. Visual field test reliability indices, test duration, global indices (mean deviation [MD], and pattern standard deviation [PSD] were compared between the 2 tests using the Wilcoxon signed-rank test and paired t-test. The performance of the Humphrey field analyzer (HFA 24-2 SITA-standard and frequency-doubling technology Matrix 24-2 tests between genders were compared with Mann-Whitney U-test. Results: Fifty-five healthy children with a mean age of 12.2 ± 1.9 years (range from 8 years to 16 years were included in this prospective study. The test durations of SAP and FDT were similar (5.2 ± 0.5 and 5.1 ± 0.2 min, respectively, P = 0.651. MD and the PSD values obtained via FDT Matrix were significantly higher than those obtained via SAP (P < 0.001, and fixation losses and false negative errors were significantly less with SAP (P < 0.05. A weak positive correlation between the two tests in terms of MD (r = 0.352, P = 0.008 and PSD (r = 0.329, P = 0.014 was observed. Conclusion: Children were able to complete both the visual test algorithms successfully within 6 min. However, SAP testing appears to be associated with less depression of the visual field indices of healthy children. FDT Matrix and SAP should not be used interchangeably in the follow-up of children.

  3. Determination of residual stresses in steel 20 comparison of the results obtained by the Barkhausen noise and X-ray diffraction

    International Nuclear Information System (INIS)

    Fernandez, L. M.; Herrera, V.; Suarez, J.C.; Merino, F.J.

    1997-01-01

    During a heat treatment (quenching, surface hardening, Thermochemical treatment) the metallic alloys undergo temperature variations and phase transformation. The resulting changes give rise to internal stresses in the piece. Phase transformation modifies the thermomechanical behavior of the material through the change of mechanical properties ( hardness, fatigue-behaviour, corrosion resistance, electric resistivity, etc.) The aim of this paper is residual stress measurements in specimens of steel-20 submitted to different heat treatment, by two non destructive methods: Barkhausen and X-ray diffraction. Brakhausen Effects utilizes the magnetic properties of ferromagnetic materials such as ferritic and perlitic steels and provides a practical tool for surface streets evaluation. X-ray streets analysis is based on the measurement of lattice strains in different directions of specimen The results obtained by two techniques are compared, avowing a good agreement

  4. Preliminary interpretations of geologic results obtained from boreholes UE25a-4, -5, -6, and -7, Yucca Mountain, Nevada Test Site

    International Nuclear Information System (INIS)

    Spengler, R.W.; Rosenbaum, J.G.

    1980-01-01

    Since 1978, the USGS (US Geological Survey) has been providing technical assistance in characterizing suitable rock masses at or contiguous to the NTS (Nevada Test Site) for long-term storage of high-level nuclear waste. Current efforts have been focused on investigating Yucca Mountain, a volcanic highland situated along the western boundary of NTS in southern Nevada. Detailed stratigraphic and structural studies have been in progress along a northeastern segment of the highland in a wedge-shaped area bounded by Basin and Range faults, most of which trend north-northeast. A series of four locally steep-walled, nearly parallel, linear washes transect the northeastern half of the area of interest and display trends similar to major faults to the northeast. Prior to the present study, drill hole UE25a-1, located about 1600 feet southeast of the edge of the area of interest, was cored to a depth of 2500 feet. Subsurface information derived from the upper 500 feet of this drill hole is included in this report to compare with recently acquired data. Surface electrical surveys have been conducted by both the University of Utah and the USGS perpendicular to the trend of the washes in an attempt to better understand factors that have influenced the present drainage pattern. Preliminary data of both pole-dipole and dipole-dipole resistivity/IP electrical methods indicate numerous vertical and horizontal discontinuities between adjacent resistive bodies that strongly suggest a broad zone of faulting, fracturing, and (or) brecciation. To verify the existence of structural discontinuities suggested by the linear washes and electrical anomalies, a drilling program was initiated in June 1979, to obtain geologic information within the southernmost of four northwest-trending washes

  5. Comparison of visual field test results obtained through Humphrey matrix frequency doubling technology perimetry versus standard automated perimetry in healthy children.

    Science.gov (United States)

    Kocabeyoglu, Sibel; Uzun, Salih; Mocan, Mehmet Cem; Bozkurt, Banu; Irkec, Murat; Orhan, Mehmet

    2013-10-01

    The aim of this study was to compare the visual field test results in healthy children obtained via the Humphrey matrix 24-2 threshold program and standard automated perimetry (SAP) using the Swedish interactive threshold algorithm (SITA)-Standard 24-2 test. This prospective study included 55 healthy children without ocular or systemic disorders who underwent both SAP and frequency doubling technology (FDT) perimetry visual field testing. Visual field test reliability indices, test duration, global indices (mean deviation [MD], and pattern standard deviation [PSD]) were compared between the 2 tests using the Wilcoxon signed-rank test and paired t-test. The performance of the Humphrey field analyzer (HFA) 24-2 SITA-standard and frequency-doubling technology Matrix 24-2 tests between genders were compared with Mann-Whitney U-test. Fifty-five healthy children with a mean age of 12.2 ± 1.9 years (range from 8 years to 16 years) were included in this prospective study. The test durations of SAP and FDT were similar (5.2 ± 0.5 and 5.1 ± 0.2 min, respectively, P = 0.651). MD and the PSD values obtained via FDT Matrix were significantly higher than those obtained via SAP (P tests in terms of MD (r = 0.352, P = 0.008) and PSD (r = 0.329, P = 0.014) was observed. Children were able to complete both the visual test algorithms successfully within 6 min. However, SAP testing appears to be associated with less depression of the visual field indices of healthy children. FDT Matrix and SAP should not be used interchangeably in the follow-up of children.

  6. Lactation curves and economic results of Saanen goats fed increasing dietary energy levels obtained by the addition of calcium salts of fatty acids

    Directory of Open Access Journals (Sweden)

    Rodrigo de Souza

    2014-02-01

    Full Text Available The objective of this study was to evaluate the use of calcium salts of fatty acids (CSFA to increase the dietary energy levels for Saanen goats and their effects on the lactation curve, dry matter intake, body weight, and economic results of the goats. Twenty multiparous goats, weighing an average of 63.5±10.3 kg, were randomly assigned to one of four treatment groups, each receiving one of the following dietary energy levels: a control diet consisting of 2.6 Mcal of metabolizable energy per kg of dry matter (Mcal ME/kg DM or a test diet supplemented with CSFA (Lactoplus® to obtain 2.7, 2.8, or 2.9 Mcal ME/kg DM. Goats were housed in individual stalls and were fed and milked twice daily. The animals were evaluated until 180 days in milk by measuring dry matter intake and milk yield. These measurements were used to calculate feed efficiencies and the cost-benefit ratio of diet and lactation curves using Wood's nonlinear model. Increasing dietary energy levels showed no effect on body weight. Supplementation with CSFA did not limit dry matter intake; however, it changed the shape of the lactation curve by promoting a late peak lactation with a longer duration. Milk yields at 180 days in milk had a quadratic increase with a maximum energy level at 2.85 Mcal ME/kg DM. Increasing the dietary energy level for Saanen goats using CSFA changes their lactation curves, with the best milk production achieved with a 2.85 Mcal ME/kg DM diet; however, the greatest economic results were obtained with a 2.7 Mcal ME/kg DM diet.

  7. Recent Advances in Solid Catalysts Obtained by Metalloporphyrins Immobilization on Layered Anionic Exchangers: A Short Review and Some New Catalytic Results

    Directory of Open Access Journals (Sweden)

    Shirley Nakagaki

    2016-02-01

    Full Text Available Layered materials are a very interesting class of compounds obtained by stacking of two-dimensional layers along the basal axis. A remarkable property of these materials is their capacity to interact with a variety of chemical species, irrespective of their charge (neutral, cationic or anionic. These species can be grafted onto the surface of the layered materials or intercalated between the layers, to expand or contract the interlayer distance. Metalloporphyrins, which are typically soluble oxidation catalysts, are examples of molecules that can interact with layered materials. This work presents a short review of the studies involving metalloporphyrin immobilization on two different anionic exchangers, Layered Double Hydroxides (LDHs and Layered Hydroxide Salts (LHSs, published over the past year. After immobilization of anionic porphyrins, the resulting solids behave as reusable catalysts for heterogeneous oxidation processes. Although a large number of publications involving metalloporphyrin immobilization on LDHs exist, only a few papers have dealt with LHSs as supports, so metalloporphyrins immobilized on LHSs represent a new and promising research field. This work also describes new results on an anionic manganese porphyrin (MnP immobilized on Mg/Al-LDH solids with different nominal Mg/Al molar ratios (2:1, 3:1 and 4:1 and intercalated with different anions (CO32− or NO3−. The influence of the support composition on the MnP immobilization rates and the catalytic performance of the resulting solid in cyclooctene oxidation reactions will be reported.

  8. Assessment of the variations in fat content in normal liver using a fast MR imaging method in comparison with results obtained by spectroscopic imaging

    International Nuclear Information System (INIS)

    Irwan, Roy; Edens, Mireille A.; Sijens, Paul E.

    2008-01-01

    A recently published Dixon-based MRI method for quantifying liver fat content using dual-echo breath-hold gradient echo imaging was validated by phantom experiments and compared with results of biopsy in two patients (Radiology 2005;237:1048-1055). We applied this method in ten healthy volunteers and compared the outcomes with the results of MR spectroscopy (MRS), the gold standard in quantifying liver fat content. Novel was the use of spectroscopic imaging yielding the variations in fat content across the liver rather than a single value obtained by single voxel MRS. Compared with the results of MRS, liver fat content according to MRI was too high in nine subjects (range 3.3-10.7% vs. 0.9-7.7%) and correct in one (21.1 vs. 21.3%). Furthermore, in one of the ten subjects the MRI fat content according to the Dixon-based MRI method was incorrect due to a (100-x) versus x percent lipid content mix-up. The second problem was fixed by a minor adjustment of the MRI algorithm. Despite systematic overestimation of liver fat contents by MRI, Spearman's correlation between the adjusted MRI liver fat contents with MRS was high (r = 0.927, P < 0.001). Even after correction of the algorithm, the problem remaining with the Dixon-based MRI method for the assessment of liver fat content,is that, at the lower end range, liver fat content is systematically overestimated by 4%. (orig.)

  9. Recent Advances in Solid Catalysts Obtained by Metalloporphyrins Immobilization on Layered Anionic Exchangers: A Short Review and Some New Catalytic Results.

    Science.gov (United States)

    Nakagaki, Shirley; Mantovani, Karen Mary; Machado, Guilherme Sippel; Castro, Kelly Aparecida Dias de Freitas; Wypych, Fernando

    2016-02-29

    Layered materials are a very interesting class of compounds obtained by stacking of two-dimensional layers along the basal axis. A remarkable property of these materials is their capacity to interact with a variety of chemical species, irrespective of their charge (neutral, cationic or anionic). These species can be grafted onto the surface of the layered materials or intercalated between the layers, to expand or contract the interlayer distance. Metalloporphyrins, which are typically soluble oxidation catalysts, are examples of molecules that can interact with layered materials. This work presents a short review of the studies involving metalloporphyrin immobilization on two different anionic exchangers, Layered Double Hydroxides (LDHs) and Layered Hydroxide Salts (LHSs), published over the past year. After immobilization of anionic porphyrins, the resulting solids behave as reusable catalysts for heterogeneous oxidation processes. Although a large number of publications involving metalloporphyrin immobilization on LDHs exist, only a few papers have dealt with LHSs as supports, so metalloporphyrins immobilized on LHSs represent a new and promising research field. This work also describes new results on an anionic manganese porphyrin (MnP) immobilized on Mg/Al-LDH solids with different nominal Mg/Al molar ratios (2:1, 3:1 and 4:1) and intercalated with different anions (CO₃(2-) or NO₃(-)). The influence of the support composition on the MnP immobilization rates and the catalytic performance of the resulting solid in cyclooctene oxidation reactions will be reported.

  10. Comparison of Hematologic and Biochemical Test Results in Blood Samples Obtained by Jugular Venipuncture Versus Nail Clip in Moluccan Cockatoos (Cacatua moluccensis).

    Science.gov (United States)

    Bennett, Tracy D; Lejnieks, Daniel V; Koepke, Hoyt; Grimson, Fiona; Szucs, Jennifer; Omaits, Kerri; Lane, Rosalie

    2015-12-01

    In birds, blood samples are often collected from the jugular, medial metatarsal, and basilic vein. Samples are sometimes collected by toe nail clip, but concerns to avoid drawing blood from the nail include pain after nail clips for blood collection, potential differences in complete blood count (CBC) results, and potential contamination with uric acid values. To compare differences in biochemical and hematologic values in blood samples obtained by jugular venipuncture versus toenail clip, blood samples were collected from Moluccan cockatoos (Cacatua moluccensis) (N = 23) and sent to a commercial laboratory for routine CBCs and serum biochemical analysis. Results showed good agreement between venipuncture and nail clip blood samples in red blood cell count, packed cell volume, heterophil count and percentage, lymphocyte count and percentage, aspartate aminotransferase, chloride, creatine phosphokinase, glucose, lactate dehydrogenase, total protein, and uric acid values. Constant bias was found in values of bile acids, cholesterol, and hemoglobin. Proportional bias toward higher values in the jugular sample were found in total white blood cell (WBC) count and inorganic phosphorus. Serum calcium plots revealed a proportional bias toward higher values in the toe nail blood when values were increased. Results suggest some differences in WBC count, bile acids, calcium, cholesterol, hemoglobin, and phosphorus values between blood samples collected by jugular venipuncture and samples collected by toe nail clip, but the differences are mostly minor and, with the possible exception of inorganic phosphorus and marginally elevated or very low WBC counts, are unlikely to affect the use or interpretation of the avian blood panel.

  11. A review of experimental results obtained in Au-Au collisions at the RHIC-BNL energies using BRAHMS experimental set-up

    International Nuclear Information System (INIS)

    Jipa, Alexandru

    2003-01-01

    Ultrarelativistic heavy ion collisions are useful tools to investigate highly excited dense nuclear matter. At sufficiently high temperature, nuclear matter is expected to undergo a phase transition to quark-gluon plasma. Therefore, new experiments have been proposed to investigate the behaviour of the highly excited dense nuclear matter. One of the experiments performed at the Relativistic Heavy Ion Collider from Brookhaven National Laboratory is the BRAHMS Experiment. In the three running years many experimental data have been obtained. These data permitted to establish significant experimental results on charged pion, charged kaon, proton and antiproton production in Au-Au collisions at 130 A GeV and 200 A GeV in CMS. The present work summarizes the main experimental results on charged particle multiplicities, rapidity distributions, momentum spectra, antiparticle to particle ratios and connects these results with some interesting physical quantities. Their dependencies on the available energies in the CMS in similar collisions are included. Interesting behaviours with the increase of this energy are reported. The most interesting are related to the behaviour of the antiproton to proton ratio on the collision centrality and on the available energy in the centre of mass system, the strangeness production, Coulomb repulsion and slope parameters of the momentum spectra. A few new steps in the knowledge of the behaviour of the highly excited and dense nuclear matter can be reported. (authors)

  12. Containment Evaluation under Severe Accidents (CESA): synthesis of the predictive calculations and analysis of the first experimental results obtained on the Civaux mock-up

    International Nuclear Information System (INIS)

    Granger, L.; Rieg, C.Y.; Touret, J.P.; Fleury, F.; Nahas, G.; Danisch, R.; Brusa, L.; Millard, A.; Laborderie, C.; Ulm, F.; Contri, P.; Schimmelpfennig, K.; Barre, F.; Firnhaber, M.; Gauvain, J; Coulon, N.; Dutton, L.M.C.; Tuson, A.

    2001-01-01

    In 1996, EDF decided to build a containment model at the scale 1:3, the MAEVA mock-up, in order to check and study the behaviour of a pre-stressed concrete containment vessel without a liner in terms of mechanical strength and leaktightness, for loadings corresponding to its design and beyond design conditions. In parallel with the construction and testing of the mock-up, a cost-shared R and D action supported by the European Union, the CESA project, is dealing with quantification of leak rates through concrete cracks and porosity, predictive calculations of the behaviour of the mock-up and analysis of the experimental results. In this paper, we propose a synthesis of the main theoretical and experimental results, obtained after 2.5 years. It should however be noted that, due to some unexpected delays in the experimental programme, quite natural with such a huge and unique experimental set-up, only the design-basis accident sequences, already performed, have been reported in this paper. The first results are nevertheless very interesting, both from a scientific and nuclear utility point of view

  13. Major Depression and the Degree of Suicidality: Results of the European Group for the Study of Resistant Depression (GSRD).

    Science.gov (United States)

    Dold, Markus; Bartova, Lucie; Fugger, Gernot; Kautzky, Alexander; Souery, Daniel; Mendlewicz, Julien; Papadimitriou, George N; Dikeos, Dimitris; Ferentinos, Panagiotis; Porcelli, Stefano; Serretti, Alessandro; Zohar, Joseph; Montgomery, Stuart; Kasper, Siegfried

    2018-06-01

    This European multicenter study aimed to elucidate suicidality in major depressive disorder. Previous surveys suggest a prevalence of suicidality in major depressive disorder of ≥50%, but little is known about the association of different degrees of suicidality with socio-demographic, psychosocial, and clinical characteristics. We stratified 1410 major depressive disorder patients into 3 categories of suicidality based on the Hamilton Rating Scale for Depression item 3 (suicidality) ratings (0=no suicidality; 1-2=mild/moderate suicidality; 3-4=severe suicidality). Chi-squared tests, analyses of covariance, and Spearman correlation analyses were applied for the data analyses. The prevalence rate of suicidality in major depressive disorder amounted to 46.67% (Hamilton Rating Scale for Depression item 3 score ≥1). 53.33% were allocated into the no, 38.44% into the mild/moderate, and 8.23% into the severe suicidality patient group. Due to the stratification of our major depressive disorder patient sample according to different levels of suicidality, we identified some socio-demographic, psychosocial, and clinical variables differentiating from the patient group without suicidality already in presence of mild/moderate suicidality (depressive symptom severity, treatment resistance, psychotic features, add-on medications in general), whereas others separated only when severe suicidality was manifest (inpatient treatment, augmentation with antipsychotics and benzodiazepines, melancholic features, somatic comorbidities). As even mild/moderate suicidality is associated with a failure of achieving treatment response, adequate recognition of this condition should be ensured in the clinical practice.

  14. Some Results on Sea Ice Rheology for the Seasonal Ice Zone, Obtained from the Deformation Field of Sea Ice Drift Pattern

    Science.gov (United States)

    Toyota, T.; Kimura, N.

    2017-12-01

    Sea ice rheology which relates sea ice stress to the large-scale deformation of the ice cover has been a big issue to numerical sea ice modelling. At present the treatment of internal stress within sea ice area is based mostly on the rheology formulated by Hibler (1979), where the whole sea ice area behaves like an isotropic and plastic matter under the ordinary stress with the yield curve given by an ellipse with an aspect ratio (e) of 2, irrespective of sea ice area and horizontal resolution of the model. However, this formulation was initially developed to reproduce the seasonal variation of the perennial ice in the Arctic Ocean. As for its applicability to the seasonal ice zones (SIZ), where various types of sea ice are present, it still needs validation from observational data. In this study, the validity of this rheology was examined for the Sea of Okhotsk ice, typical of the SIZ, based on the AMSR-derived ice drift pattern in comparison with the result obtained for the Beaufort Sea. To examine the dependence on a horizontal scale, the coastal radar data operated near the Hokkaido coast, Japan, were also used. Ice drift pattern was obtained by a maximum cross-correlation method with grid spacings of 37.5 km from the 89 GHz brightness temperature of AMSR-E for the entire Sea of Okhotsk and the Beaufort Sea and 1.3 km from the coastal radar for the near-shore Sea of Okhotsk. The validity of this rheology was investigated from a standpoint of work rate done by deformation field, following the theory of Rothrock (1975). In analysis, the relative rates of convergence were compared between theory and observation to check the shape of yield curve, and the strain ellipse at each grid cell was estimated to see the horizontal variation of deformation field. The result shows that the ellipse of e=1.7-2.0 as the yield curve represents the observed relative conversion rates well for all the ice areas. Since this result corresponds with the yield criterion by Tresca and

  15. On the influence of infiltration of radioactive beds by flushing fluid on γ-ray logging results obtained from uranium deposit No. 387

    International Nuclear Information System (INIS)

    Ren Bingxiang; Zhang Yuechun; Ai Shuyi.

    1985-01-01

    A large number of field logging data obtained during the course of exploration on uranium deposit No. 387 show when the radioactive beds are encountered by drill holes and the drilling continues the γ-ray intensity decreases. It is considered that the escape of emanation does not considerably influence the logging results. Therefore, based upon the experiment of immerseing ores in fluid and geological and hydrogeological data of the deposit, the hypotheses that the γ-ray intensity in drill hole is closely related with the infiltration of flushing fluid is suggested. The ore bodies are strictly controlled by faults. Most of the uranium and thorium are absorbed by pelitic-carbonaceous cements or fill the porous spaces in structural breccia and cataclasite. They are easy to dissolve in water. Moreover, the ore-bearing structures are the unique water aquifers which is under pressure. As the level of flushing fluid is higher than the pressure head so it continuously pours into the ore-bearing beds, resulting in the infiltration of U and Ra. Consequently, the radioactivity detected is low

  16. Answers to the questions about food irradiation. Concerning results of animal experiments in the specified integrated research. Data carrying a problem in human health were obtained?

    International Nuclear Information System (INIS)

    Ito, Hitoshi

    2007-01-01

    Experts of Food and Agriculture Organization (FAO)/ International Atomic Energy Agency (IAEA)/ World Health Organization (WHO) committee obtained their conclusion in 1980 that food irradiated with <10 kGy of radiation is safe for human health, which is now globally approved. However, in Japan, there have been still opposite opinions based on the doubt in the title on the safety of irradiated food. In this paper, the author answers those questions as he was a member to arrange the Research in the title for food irradiation. Described are data presentation and explanation about results of toxicity studies of diets added with irradiated materials of: weight reductions in rat ovary by irradiated potato (ip) in chronic studies, and in mouse testicle and ovary of F3 generation from the ancestor mice kept on diet with irradiated onion (io); bone malformation in mice by io; and reduction of body weight gain in female rats by ip and increase of mortality of male rats by ip. These are analyzed on the aspects of radiation dose-response, sustained tendency of results throughout the living period or generation, and apparent abnormality by other factors; and normal variation due to individual difference is pointed out to contribute to these findings. The safety test of irradiated food has been conducted valid not only in animal experiments but also other tests like genotoxicity and analysis of radiation-degraded products. (R.T.)

  17. Cost-effectiveness of family psychoeducation to prevent relapse in major depression: Results from a randomized controlled trial

    Directory of Open Access Journals (Sweden)

    Shimodera Shinji

    2012-05-01

    Full Text Available Abstract Background Family psychoeducation is a relatively simple and straightforward intervention whose prophylactic effectiveness and cost-effectiveness is well-established for schizophrenia. We have recently demonstrated its effectiveness for unipolar depression, but its cost-effectiveness has never been examined. We hereby report a cost-effectiveness analysis alongside a randomized controlled trial in order to assess its cost-effectiveness for preventing relapse/recurrence in depression. Methods Fifty-seven patients diagnosed with major depression and undergoing its maintenance treatment, and their primary family members were randomized to treatment as usual (TAU only or to TAU plus family psychoeducation, which consisted of four 2-hour multiple-family sessions consisting of didactic lectures about depression (30 minutes and group discussion and problem solving (60–90 minutes. The economic analyses were undertaken from the perspective of the National Health Insurance (NHI, assuming the most reasonable price of US$50 per psychoeducation session per patient. The main outcome measures included relapse-free days and direct costs to the NHI. Results The intervention group enjoyed 272 (SD: 7.1 relapse-free days, while the control group spent 214 (SD: 90.8 relapse-free days (Cox proportional hazard ratio = 0.17, 95%CI: 0.04 to 0.75, p = 0.002. Cost-effectiveness acceptability curves suggested that the family psychoeducation has 90% or more chances of being cost-effective if the decision-maker is prepared to pay US$20 for one additional relapse-free day. This cost-effectiveness finding was robust when the price for family psychoeducation ranged between 50% to 150% of the baseline scenario in sensitivity analyses. If a relapse-free day is considered to be worth $30 or more, all the pricing scenarios have a close to 100% probability of being cost-effective. Conclusion Family psychoeducation is effective in the relapse prevention of

  18. Wildlife Reservoirs of Canine Distemper Virus Resulted in a Major Outbreak in Danish Farmed Mink (Neovison vison)

    DEFF Research Database (Denmark)

    Trebbien, Ramona; Chriél, Mariann; Struve, Tina

    2014-01-01

    A major outbreak of canine distemper virus (CDV) in Danish farmed mink (Neovison vison) started in the late summer period of 2012. At the same time, a high number of diseased and dead wildlife species such as foxes, raccoon dogs, and ferrets were observed. To track the origin of the outbreak virus...

  19. A comparison of two methods for prediction of response and rates of inbreeding in selected populations with the results obtained in two selection experiments

    Directory of Open Access Journals (Sweden)

    Verrier Etienne

    2005-05-01

    Full Text Available Abstract Selection programmes are mainly concerned with increasing genetic gain. However, short-term progress should not be obtained at the expense of the within-population genetic variability. Different prediction models for the evolution within a small population of the genetic mean of a selected trait, its genetic variance and its inbreeding have been developed but have mainly been validated through Monte Carlo simulation studies. The purpose of this study was to compare theoretical predictions to experimental results. Two deterministic methods were considered, both grounded on a polygenic additive model. Differences between theoretical predictions and experimental results arise from differences between the true and the assumed genetic model, and from mathematical simplifications applied in the prediction methods. Two sets of experimental lines of chickens were used in this study: the Dutch lines undergoing true truncation mass selection, the other lines (French undergoing mass selection with a restriction on the representation of the different families. This study confirmed, on an experimental basis, that modelling is an efficient approach to make useful predictions of the evolution of selected populations although the basic assumptions considered in the models (polygenic additive model, normality of the distribution, base population at the equilibrium, etc. are not met in reality. The two deterministic methods compared yielded results that were close to those observed in real data, especially when the selection scheme followed the rules of strict mass selection: for instance, both predictions overestimated the genetic gain in the French experiment, whereas both predictions were close to the observed values in the Dutch experiment.

  20. Obtaining land cover changes information from multitemporal analysis of Landsat-TM images: results from a case study in West African dryland

    Science.gov (United States)

    Nutini, F.; Boschetti, M.; Brivio, P. A.; Antoninetti, M.

    2012-04-01

    The Sahelian belt of West Africa is a semiarid region characterized by wide climate variations, which can in turn affect the livelihood of local populations particularly in rangeland areas, as happens during the dramatic food crisis in the 70-80s caused by rainfall scarcity. The monitoring of natural resources and rainfed agricultural activities, with the aim to provide information to support Sahelian food security action, needs the production of detailed thematic maps as emphasized by several scientific papers. In this framework, a study was conducted to develop a method to exploit time series of remote sensed satellite data to 1) provide reliable land cover (LC) map at local scale in a dry region and 2) obtain a LC change (LCC) map that contribute to identify the plausible causes of local environmental instability. Satellite images used for this work consist in a time series of Landsat Thematic Mapper (TM) (path row 195-50) acquired in the 2000 (6 scenes) and 2007 (9 scenes) from February (Dry season) to September (end of wet season). The study investigates the different contribution provided by spectra information of a single Landsat TM image and by time series of derived NDVI. Different tests have been conducted with different combination of data set (spectral and temporal)in order to identify the best approach to obtain a LC map in five classes of interest: Shrubland, Cultivated Land, Water body, Herbaceous vegetation and Bare soil. The best classification approach is exposed and applied on two years in the last decade. The comparison between this two LC results in land cover change map, that displays the changes of vegetation patterns that have been characterized the area. The discussed results show a largely stable dryland region, but locally characterized by hot-spot of decreasing in natural vegetation inside the rangelands and an increasing of cultivations along fossil valleys where human activities are slightly intense. The discussion shows that this hot

  1. Comparison of the identification results of Candida species obtained by BD Phoenix™ and Maldi-TOF (Bruker Microflex LT Biotyper 3.1).

    Science.gov (United States)

    Marucco, Andrea P; Minervini, Patricia; Snitman, Gabriela V; Sorge, Adriana; Guelfand, Liliana I; Moral, Laura López

    2018-02-05

    In patients with invasive fungal infections, the accurate and rapid identification of the genus Candida is of utmost importance since antimycotic sensitivity is closely related to the species. The aim of the present study was to compare the identification results of species of the genus Candida obtained by BD Phoenix™ (Becton Dickinson [BD]) and Maldi-TOF MS (Bruker Microflex LT Biotyper 3.1). A total of 192 isolates from the strain collection belonging to the Mycology Network of the Autonomous City of Buenos Aires, Argentina, were analyzed. The observed concordance was 95%. Only 10 strains (5%) were not correctly identified by the BD Phoenix™ system. The average identification time with the Yeast ID panels was 8h 22min. The BD Phoenix™ system proved to be a simple, reliable and effective method for identifying the main species of the genus Candida. Copyright © 2017 Asociación Argentina de Microbiología. Publicado por Elsevier España, S.L.U. All rights reserved.

  2. Influence of the microstructure on the resulting 18R martensitic transformation of polycrystalline Cu−Al−Zn thin films obtained by sputtering and reactive annealing

    International Nuclear Information System (INIS)

    Domenichini, P.; Condó, A.M.; Soldera, F.; Sirena, M.; Haberkorn, N.

    2016-01-01

    We report the influence of the microstructure on the martensitic transformation in polycrystalline Cu−Zn−Al thin films with 18R structure. The films are grown in two steps. First, Cu−Al thin films are obtained by DC sputtering. Second, the Zn is introduced in the Cu−Al thin films by the annealing them together with a bulk Cu−Zn−Al reference. The crystalline structure of the films was analyzed by X-ray diffraction and transmission electron microscopy. The martensitic transformation temperature was measured by electrical transport using conventional four probe geometry. It was observed that temperatures above 973 K are necessary for zincification of the samples to occur. The resulting martensitic transformation and its hysteresis (barrier for the transformation) depend on the grain size, topology and films thickness. - Highlights: • Polycrystalline Cu−Al−Zn thin films with nanometric grain size are sintered. • Influence of thermal annealing process on the microstructure is analyzed. • Martensitic transformation of Cu−Al−Zn thin films is strongly affected by the microstructure.

  3. Influence of the microstructure on the resulting 18R martensitic transformation of polycrystalline Cu−Al−Zn thin films obtained by sputtering and reactive annealing

    Energy Technology Data Exchange (ETDEWEB)

    Domenichini, P. [Instituto Balseiro, Bustillo 9500, S. C. de Bariloche (Argentina); Condó, A.M. [Instituto Balseiro, Bustillo 9500, S. C. de Bariloche (Argentina); Centro Atómico Bariloche, Comisión Nacional de Energía Atómica, Av. Bustillo 9500, 8400 San Carlos de Bariloche (Argentina); Soldera, F. [Department of Materials Science & Engineering, Saarland University, D-66123 Saarbruecken (Germany); Sirena, M. [Instituto Balseiro, Bustillo 9500, S. C. de Bariloche (Argentina); Centro Atómico Bariloche, Comisión Nacional de Energía Atómica, Av. Bustillo 9500, 8400 San Carlos de Bariloche (Argentina); Haberkorn, N., E-mail: nhaberk@cab.cnea.gov.ar [Instituto Balseiro, Bustillo 9500, S. C. de Bariloche (Argentina); Centro Atómico Bariloche, Comisión Nacional de Energía Atómica, Av. Bustillo 9500, 8400 San Carlos de Bariloche (Argentina)

    2016-04-15

    We report the influence of the microstructure on the martensitic transformation in polycrystalline Cu−Zn−Al thin films with 18R structure. The films are grown in two steps. First, Cu−Al thin films are obtained by DC sputtering. Second, the Zn is introduced in the Cu−Al thin films by the annealing them together with a bulk Cu−Zn−Al reference. The crystalline structure of the films was analyzed by X-ray diffraction and transmission electron microscopy. The martensitic transformation temperature was measured by electrical transport using conventional four probe geometry. It was observed that temperatures above 973 K are necessary for zincification of the samples to occur. The resulting martensitic transformation and its hysteresis (barrier for the transformation) depend on the grain size, topology and films thickness. - Highlights: • Polycrystalline Cu−Al−Zn thin films with nanometric grain size are sintered. • Influence of thermal annealing process on the microstructure is analyzed. • Martensitic transformation of Cu−Al−Zn thin films is strongly affected by the microstructure.

  4. The Escompte - Marseille 2001 International Field Experiment: Ground Based and Lidar Results Obtained At St. Chamas By The Epfl Mobile Laboratory

    Science.gov (United States)

    Balin, I.; Jimenez, R.; Simeonov, V.; Ristori, P.; Navarette, M.; van den Bergh, H.; Calpini, B.

    The assessment of the air pollution problems in term of understanding of the non- linear chemical mechanisms, the transport or the meteorological processes, and the choice of the abatement strategies could be based on the air pollution models. Nowa- days, very few of these models were validated due to the lack of 3D measurements. The goal of the ESCOMPTE experiment was to provide such of 3D database in order to constrain the air pollution models. The EPFL-LPA mobile laboratory was part of the ESCOMPTE extensive network and was located on the northern side of the Berre Lake at St.Chamas. In this framework, measurements of the air pollutants (O3, SO2, NOx, polycyclic aromatic hydrocarbons, black carbon and particulate matter of less than 10 microns mean diameter) and meteorological parameters (wind, temperature, pressure and relative humidity) were continuously performed from June 10 to July 13, 2001. They were combined with ground based lidar observations for ozone and aerosol estimation from 100m above ground level up to the free troposphere at ca.7 km agl. This paper will present an overview of the results obtained and will highlight one of the intensive observation period (IOP) during which clean air conditions were initially observed followed by highly polluted air masses during the second half of the IOP.

  5. Results of a real-world study on vortioxetine in patients with major depressive disorder in South East Asia (REVIDA).

    Science.gov (United States)

    Chin, Cheuk Ngen; Zain, Azhar; Hemrungrojn, Solaphat; Ung, Eng Khean; Kwansanit, Patanon; Au Yong, Koon Choong; Chong, Marvin Swee Woon; Inpa, Chalowat; Yen, Teck Hoe; Yeoh, Boon Beng David; Tay, Liam Kai; Bernardo, Carmina; Lim, Lionel Chee-Chong; Yap, Chin Hong; Fones, Calvin; Nayak, Ashwini; Nelleman, Lars

    2018-05-17

    The REVIDA study aimed to assess the evolution of major depression symptoms in South East Asian (SEA) patients treated with vortioxetine for major depression in real-world clinical practice. This non-interventional study was conducted from Aug 2016 to Apr 2017. A total of 138 patients (aged 18-65 years) with an active episode of major depression were recruited from Malaysia, Philippines, Singapore, and Thailand. Vortioxetine was initiated on the first visit and patients were followed for 3 months. Depression severity was assessed using the PHQ-9 questionnaire (patient-assessed) and CGI-S scale (physician-assessed); cognitive function was assessed with the PDQ-D questionnaire; work productivity and activity impairment (WPAI) was assessed with the WPAI questionnaire. At baseline, 89.9% of patients were moderately to severely depressed (PHQ-9 score ≥ 10). During the 3-month treatment period, mean±SD PHQ-9 score decreased from 18.7±5.7 to 5.0±5.3, mean±SD CGI-S score decreased from 4.4±0.7 to 2.2±1.1, and mean±SD PDQ-D score decreased from 42.1±18.8 to 13.4±13.0. By month 3, response and remission rates reached 80.8% and 59.0%, respectively. Work productivity loss decreased from 73.6% to 30.5%, while activity impairment decreased from 71.5% to 24.6%. Positive correlations were observed between PHQ-9, PDQ-D, and WPAI work productivity loss and activity impairment. By month 3, 82.0% of patients were either not depressed or only mildly depressed (PHQ-9 score ≤ 9). In real-world clinical settings, vortioxetine was effective in reducing depression severity and improving cognitive function and work productivity in SEA patients with major depression.

  6. Ziprasidone Augmentation of Escitalopram for Major Depressive Disorder: Efficacy Results From a Randomized, Double-Blind, Placebo-Controlled Study.

    Science.gov (United States)

    Papakostas, George I; Fava, Maurizio; Baer, Lee; Swee, Michaela B; Jaeger, Adrienne; Bobo, William V; Shelton, Richard C

    2015-12-01

    The authors sought to test the efficacy of adjunctive ziprasidone in adults with nonpsychotic unipolar major depression experiencing persistent symptoms after 8 weeks of open-label treatment with escitalopram. This was an 8-week, randomized, double-blind, parallel-group, placebo-controlled trial conducted at three academic medical centers. Participants were 139 outpatients with persistent symptoms of major depression after an 8-week open-label trial of escitalopram (phase 1), randomly assigned in a 1:1 ratio to receive adjunctive ziprasidone (escitalopram plus ziprasidone, N=71) or adjunctive placebo (escitalopram plus placebo, N=68), with 8 weekly follow-up assessments. The primary outcome measure was clinical response, defined as a reduction of at least 50% in score on the 17-item Hamilton Depression Rating Scale (HAM-D). The Hamilton Anxiety Rating scale (HAM-A) and Visual Analog Scale for Pain were defined a priori as key secondary outcome measures. Rates of clinical response (35.2% compared with 20.5%) and mean improvement in HAM-D total scores (-6.4 [SD=6.4] compared with -3.3 [SD=6.2]) were significantly greater for the escitalopram plus ziprasidone group. Several secondary measures of antidepressant efficacy also favored adjunctive ziprasidone. The escitalopram plus ziprasidone group also showed significantly greater improvement on HAM-A score but not on Visual Analog Scale for Pain score. Ten (14%) patients in the escitalopram plus ziprasidone group discontinued treatment because of intolerance, compared with none in the escitalopram plus placebo group. Ziprasidone as an adjunct to escitalopram demonstrated antidepressant efficacy in adult patients with major depressive disorder experiencing persistent symptoms after 8 weeks of open-label treatment with escitalopram.

  7. Relationship between signal intensity of blood flow in the pulmonary artery obtained by magnetic resonance imaging and results of right cardiac catheterization in patients with pulmonary disease

    Energy Technology Data Exchange (ETDEWEB)

    Yuguchi, Yasutoshi; Nagao, Keiichi; Kouno, Norihiro; Tanabe, Nobuhiro; Okita, Shinya; Tojima, Hirokazu; Okada, Osamu; Kuriyama, Takayuki [Chiba Univ. (Japan). School of Medicine; Yamaguchi, Tetsuo

    1992-08-01

    Electrocardiogram-gated spin-echo magnetic resonance (MR) images of the chest were obtained in five normal controls and 35 patients with pulmonary disease (11 chronic obstructive pulmonary disease, 6 pulmonary thromboembolism, 5 primary pulmonary hypertension, 4 interstitial pulmonary disease, 4 pulmonary hypertension with disturbance of portal circulation, and 5 other diseases) who underwent right cardiac catheterization. In transverse images at the level of the right main pulmonary artery (rPA) and sagittal images at the level through the midsternal line and the spinal cord, the signal intensity of blood flow in the rPA was quantitatively evaluated, and the correlations with the MR signal intensity of intravascular flow and the parameters of hemodynamics were studied. In diastole MR images of both normal controls and patients mostly showed a significant signal and visible flow images. In systolic MR images, the mean values of hemodynamic parameters (mean pulmonary arterial pressure (mPAP), pulmonary arteriolar resistance (PAR), and cardiac index (CI)) were abnormal in patients with significant signal intensity of flow compared with those in patients without sufficient MR signal. The signal intensity was not correlated with mPAP; however, it significantly increased as PAR increased, and it increased as CI decreased both in diastole and in systole. Especially in systole, there was good correlation between the signal intensity in transverse MR images and CI and between signal intensity in sagittal MR images and PAR . These results suggest that the signal intensity of blood flow in the rPA on MR images can be used as an index of the severity of right heart failure associated with pulmonary disease. MR imaging is a useful modality to evaluate pulmonary circulation disturbance because of its ability to assess blood flow in the pulmonary artery noninvasively without interference from other structures such as bone and normal lung. (J.P.N.).

  8. Using some results about the Lie evolution of differential operators to obtain the Fokker-Planck equation for non-Hamiltonian dynamical systems of interest

    Science.gov (United States)

    Bianucci, Marco

    2018-05-01

    Finding the generalized Fokker-Planck Equation (FPE) for the reduced probability density function of a subpart of a given complex system is a classical issue of statistical mechanics. Zwanzig projection perturbation approach to this issue leads to the trouble of resumming a series of commutators of differential operators that we show to correspond to solving the Lie evolution of first order differential operators along the unperturbed Liouvillian of the dynamical system of interest. In this paper, we develop in a systematic way the procedure to formally solve this problem. In particular, here we show which the basic assumptions are, concerning the dynamical system of interest, necessary for the Lie evolution to be a group on the space of first order differential operators, and we obtain the coefficients of the so-evolved operators. It is thus demonstrated that if the Liouvillian of the system of interest is not a first order differential operator, in general, the FPE structure breaks down and the master equation contains all the power of the partial derivatives, up to infinity. Therefore, this work shed some light on the trouble of the ubiquitous emergence of both thermodynamics from microscopic systems and regular regression laws at macroscopic scales. However these results are very general and can be applied also in other contexts that are non-Hamiltonian as, for example, geophysical fluid dynamics, where important events, like El Niño, can be considered as large time scale phenomena emerging from the observation of few ocean degrees of freedom of a more complex system, including the interaction with the atmosphere.

  9. An audit of the contribution to post-mortem examination diagnosis of individual analyte results obtained from biochemical analysis of the vitreous.

    Science.gov (United States)

    Mitchell, Rebecca; Charlwood, Cheryl; Thomas, Sunethra Devika; Bellis, Maria; Langlois, Neil E I

    2013-12-01

    Biochemical analysis of the vitreous humor from the eye is an accepted accessory test for post-mortem investigation of cause of death. Modern biochemical analyzers allow testing of a range of analytes from a sample. However, it is not clear which analytes should be requested in order to prevent unnecessary testing (and expense). The means and standard deviation of the values obtained from analysis of the vitreous humor for sodium, potassium, chloride, osmolality, glucose, ketones (β-hydroxybutyrate), creatinine, urea, calcium, lactate, and ammonia were calculated from which the contribution of each analyte was reviewed in the context of post-mortem findings and final cause of death. For sodium 32 cases were regarded as high (more than one standard deviation above the mean), from which 9 contributed to post-mortem diagnosis [drowning (4), heat related death (2), diabetic hyperglycemia (2), and dehydration (1)], but 25 low values (greater than one standard deviation below the mean) made no contribution. For chloride 29 high values contributed to 4 cases--3 drowning and 1 heat-related, but these were all previously identified by a high sodium level. There were 29 high and 35 low potassium values, none of which contributed to determining the final cause of death. Of 22 high values of creatinine, 12 contributed to a diagnosis of renal failure. From 32 high values of urea, 18 contributed to 16 cases of renal failure (2 associated with diabetic hyperglycemia), 1 heat-related death, and one case with dehydration. Osmolarity contributed to 12 cases (5 heat-related, 4 diabetes, 2 renal failure, and 1 dehydration) from 36 high values. There was no contribution from 32 high values and 19 low values of calcium and there was no contribution from 4 high and 2 low values of ammonia. There were 11 high values of glucose, which contributed to the diagnosis of 6 cases of diabetic hyperglycemia and 21 high ketone levels contributed to 8 cases: 4 diabetic ketosis, 3 hypothermia, 3

  10. A comparison of two methods for prediction of response and rates of inbreeding in selected populations with the results obtained in two selection experiments

    NARCIS (Netherlands)

    Loywyck, V.; Bijma, P.; Pinard-van der Laan, M.H.; Arendonk, van J.A.M.; Verrier, E.

    2005-01-01

    Selection programmes are mainly concerned with increasing genetic gain. However, short-term progress should not be obtained at the expense of the within-population genetic variability. Different prediction models for the evolution within a small population of the genetic mean of a selected trait,

  11. Wildlife Reservoirs of Canine Distemper Virus Resulted in a Major Outbreak in Danish Farmed Mink (Neovison vison)

    Science.gov (United States)

    Trebbien, Ramona; Chriel, Mariann; Struve, Tina; Hjulsager, Charlotte Kristiane; Larsen, Gitte; Larsen, Lars Erik

    2014-01-01

    A major outbreak of canine distemper virus (CDV) in Danish farmed mink (Neovison vison) started in the late summer period of 2012. At the same time, a high number of diseased and dead wildlife species such as foxes, raccoon dogs, and ferrets were observed. To track the origin of the outbreak virus full-length sequencing of the receptor binding surface protein hemagglutinin (H) was performed on 26 CDV's collected from mink and 10 CDV's collected from wildlife species. Subsequent phylogenetic analyses showed that the virus circulating in the mink farms and wildlife were highly identical with an identity at the nucleotide level of 99.45% to 100%. The sequences could be grouped by single nucleotide polymorphisms according to geographical distribution of mink farms and wildlife. The signaling lymphocytic activation molecule (SLAM) receptor binding region in most viruses from both mink and wildlife contained G at position 530 and Y at position 549; however, three mink viruses had an Y549H substitution. The outbreak viruses clustered phylogenetically in the European lineage and were highly identical to wildlife viruses from Germany and Hungary (99.29% – 99.62%). The study furthermore revealed that fleas (Ceratophyllus sciurorum) contained CDV and that vertical transmission of CDV occurred in a wild ferret. The study provides evidence that wildlife species, such as foxes, play an important role in the transmission of CDV to farmed mink and that the virus may be maintained in the wild animal reservoir between outbreaks. PMID:24454897

  12. Wildlife reservoirs of canine distemper virus resulted in a major outbreak in Danish farmed mink (Neovison vison.

    Directory of Open Access Journals (Sweden)

    Ramona Trebbien

    Full Text Available A major outbreak of canine distemper virus (CDV in Danish farmed mink (Neovison vison started in the late summer period of 2012. At the same time, a high number of diseased and dead wildlife species such as foxes, raccoon dogs, and ferrets were observed. To track the origin of the outbreak virus full-length sequencing of the receptor binding surface protein hemagglutinin (H was performed on 26 CDV's collected from mink and 10 CDV's collected from wildlife species. Subsequent phylogenetic analyses showed that the virus circulating in the mink farms and wildlife were highly identical with an identity at the nucleotide level of 99.45% to 100%. The sequences could be grouped by single nucleotide polymorphisms according to geographical distribution of mink farms and wildlife. The signaling lymphocytic activation molecule (SLAM receptor binding region in most viruses from both mink and wildlife contained G at position 530 and Y at position 549; however, three mink viruses had an Y549H substitution. The outbreak viruses clustered phylogenetically in the European lineage and were highly identical to wildlife viruses from Germany and Hungary (99.29% - 99.62%. The study furthermore revealed that fleas (Ceratophyllus sciurorum contained CDV and that vertical transmission of CDV occurred in a wild ferret. The study provides evidence that wildlife species, such as foxes, play an important role in the transmission of CDV to farmed mink and that the virus may be maintained in the wild animal reservoir between outbreaks.

  13. Oxidative stress in major depressive and anxiety disorders, and the association with antidepressant use; results from a large adult cohort.

    Science.gov (United States)

    Black, C N; Bot, M; Scheffer, P G; Penninx, B W J H

    2017-04-01

    Oxidative stress has been implicated in the pathophysiology of major depressive disorder (MDD) and anxiety disorders and may be influenced by antidepressant use. This study investigated the association of oxidative stress, measured by plasma levels of F2-isoprostanes and 8-hydroxy-2'-deoxyguanosine (8-OHdG) reflecting oxidative lipid and DNA damage respectively, with MDD, anxiety disorders and antidepressant use in a large cohort. Data was derived from the Netherlands Study of Depression and Anxiety including patients with current (N = 1619) or remitted (N = 610) MDD and/or anxiety disorder(s) (of which N = 704 antidepressant users) and 612 controls. Diagnoses were established with the Composite International Diagnostic Interview. Plasma 8-OHdG and F2-isoprostanes were measured using LC-MS/MS. ANCOVA was performed adjusted for sampling, sociodemographic, health and lifestyle variables. F2-isoprostanes did not differ between controls and patients, or by antidepressant use. Patients with current disorders had lower 8-OHdG (mean 42.1 pmol/l, 95% CI 40.4-43.8) compared to controls (45.0 pmol/l, 95% CI 42.9-47.2; p anxiety disorders), and all antidepressant types (SSRIs, TCAs, other antidepressants). Contrary to previous findings this large-scale study found no increased oxidative stress in MDD and anxiety disorders. Antidepressant use was associated with lower oxidative DNA damage, suggesting antidepressants may have antioxidant effects.

  14. Clinical Significance of the Number of Depressive Symptoms in Major Depressive Disorder: Results from the CRESCEND Study.

    Science.gov (United States)

    Park, Seon-Cheol; Sakong, Jeongkyu; Koo, Bon Hoon; Kim, Jae-Min; Jun, Tae-Youn; Lee, Min-Soo; Kim, Jung-Bum; Yim, Hyeon-Woo; Park, Yong Chon

    2016-04-01

    Our study aimed to establish the relationship between the number of depressive symptoms and the clinical characteristics of major depressive disorder (MDD). This would enable us to predict the clinical significance of the number of depressive symptoms in MDD patients. Using data from the Clinical Research Center for Depression (CRESCEND) study in Korea, 853 patients with DSM-IV MDD were recruited. The baseline and clinical characteristics of groups with different numbers of depressive symptoms were compared using the χ(2) test for discrete variables and covariance (ANCOVA) for continuous variables. In addition, the scores of these groups on the measurement tools were compared by ANCOVA after adjusting the potential effects of confounding variables. After adjusting the effects of monthly income and history of depression, a larger number of depressive symptoms indicated higher overall severity of depression (F [4, 756] = 21.458, P depressive symptoms (F [4, 767] = 19.145, P depressive symptoms can be used as an index of greater illness burden in clinical psychiatry.

  15. Prevalence of major depressive disorder and socio-demographic correlates: Results of a representative household epidemiological survey in Beijing, China.

    Science.gov (United States)

    Liu, Jing; Yan, Fang; Ma, Xin; Guo, Hong-Li; Tang, Yi-Lang; Rakofsky, Jeffrey J; Wu, Xiao-Mei; Li, Xiao-Qiang; Zhu, Hong; Guo, Xiao-Bing; Yang, Yang; Li, Peng; Cao, Xin-Dong; Li, Hai-Ying; Li, Zhen-Bo; Wang, Ping; Xu, Qiu-Yue

    2015-07-01

    Major depressive disorder (MDD) is the most prevalent mental disorder in the general population and has been associated with socioeconomic factors. Beijing has undergone significant socioeconomic changes in last decade, however no large-scale community epidemiological surveys of MDD have been conducted in Beijing since 2003. To determine the prevalence of MDD and its socio-demographic correlates in a representative household sample of the general population in Beijing, China. Data were collected from the 2010 representative household epidemiological survey of mental disorders in Beijing. The multistage cluster random sampling method was used to select qualified subjects in 18 districts and counties, and then face-to-face interviews were administered using the Chinese version of Structured Clinical Interview for DSM-IV-TR Axis I Disorders-Patient Edition (SCID-I/P) during November 1, 2010 to December 31, 2010. 19,874 registered permanent residents were randomly identified and 16,032 (response rate=80.7%) completed face-to-face interviews. The time-point and life-time prevalence rates of MDD were estimated to be 1.10% (95% CI: 0.94-1.26%) and 3.56% (95% CI: 3.27-3.85%) respectively. Significant differences were found in sex, age, location of residence, marital status, education, employment status, personal/family monthly income, perception of family environment and relationship with others, when comparing residents with MDD to those without MDD. Those who were female, aged 45 or above, reported low family income, or reported an "average" or "poor" family environment were associated with a higher risk of MDD. The prevalence of MDD reported in this survey is relatively lower than that in other western countries. Female sex, age older than 45, low family income, and poor family environment appear to be independent risk factors for MDD. Copyright © 2015 Elsevier B.V. All rights reserved.

  16. Potential Relationship between Season of Birth and Clinical Characteristics in Major Depressive Disorder in Koreans: Results from the CRESCEND Study.

    Science.gov (United States)

    Park, Seon-Cheol; Sakong, Jeong-Kyu; Koo, Bon Hoon; Kim, Jae-Min; Jun, Tae-Youn; Lee, Min-Soo; Kim, Jung-Bum; Yim, Hyeon-Woo; Park, Yong Chon

    2016-05-01

    We aimed to examine the potential relationship between season of birth (SOB) and clinical characteristics in Korean patients with unipolar non-psychotic major depressive disorder (MDD). Using data from the Clinical Research Center for Depression (CRESCEND) study in South Korea, 891 MDD patients were divided into two groups, those born in spring/summer (n=457) and those born in autumn/winter (n=434). Measurement tools comprising the Hamilton Depression Rating Scale, Hamilton Anxiety Rating Scale, Brief Psychiatric Rating Scale, Scale for Suicidal Ideation, Clinical Global Impression of severity, Social and Occupation Functional Assessment Scale, WHO Quality of Life assessment instrument-abbreviated version, Alcohol Use Disorder Identification Test, and Temperament and Character Inventory were used to evaluate depression, anxiety, overall symptoms, suicidal ideation, global severity, social function, quality of life, drinking, and temperament and character, respectively. Using independent t-tests for continuous variables and χ² tests for discrete variables, the clinical characteristics of the two groups were compared. MDD patients born in spring/summer were on average younger at onset of first depressive episode (t=2.084, p=0.038), had greater loss of concentration (χ²=4.589, p=0.032), and were more self-directed (t=2.256, p=0.025) than those born in autumn/winter. Clinically, there was a trend for the MDD patients born in spring/summer to display the contradictory characteristics of more severe clinical course and less illness burden; this may have been partly due to a paradoxical effect of the 5-HT system.

  17. Recession wedge trochleoplasty as an additional procedure in the surgical treatment of patellar instability with major trochlear dysplasia: early results.

    Science.gov (United States)

    Thaunat, M; Bessiere, C; Pujol, N; Boisrenoult, P; Beaufils, P

    2011-12-01

    The importance of a dysplastic trochlea as a component of patellar instability has long been recognized. An original trochleoplasty technique consisting in retro-trochlear recession wedge osteotomy was described by Goutallier et al. The aim is not to fashion a groove but to reduce the bump without modifying patellofemoral congruence. This retrospective study reports the operative technique and short-term outcomes of a consecutive case series of 17 patients (19 knees) who underwent recession wedge trochleoplasty for patellofemoral instability associated with severe trochlear dysplasia. Other contributing factors of patellar instability were also corrected as part of the surgical procedure: tibial tuberosity transfer (n=18), MPFL reconstruction (n=8). Minimum follow-up was 12 months (mean, 34 months; range, 12 to 71 months). The trochlear prominence was reduced from a mean 4.8mm (range, 0 to 8mm) to -0.8mm (range, -8 to 6mm). Patellar tilt was reduced from a mean 14° (range, 6° to 26°) to 6° (range, -1° to 24°). Two cases showed recurrent patellofemoral instability. Mean Kujala, KOOS and IKDC score were respectively 80 (± 17), 70 (± 18) and 67 (± 17) at last follow-up. Three patients required further operations, apart from removal of metal screws: arthroscopic arthrolysis for stiffness (n=1), revision for tibial tuberosity non-union (n=1), and supratrochlear exostosectomy (n=1). Recession wedge trochleoplasty is a feasible additional procedure addressing bony trochlear abnormality in the surgical treatment of patellar instability. Our attitude is to perform it never in isolation but associated to realignment of the extensor apparatus according to the à la carte surgery concept. It seems to be effective in preventing future patellar dislocation and reducing anterior knee pain in case of painful patellofemoral instability with a major dysplastic trochlea, or in revision cases when other realignment procedures have failed. Copyright © 2011 Elsevier Masson SAS

  18. A comparison between the Structural Results obtained by X-ray Single Crystal Data and by Neutron Powder Data for BaVs/sb3/

    International Nuclear Information System (INIS)

    Marezio, M.

    1986-01-01

    The structure of BaVs/sb3/, as refined from X-ray single-crystal data to an R factor of 0.011, is compared to the structure of the same compound obtained from neutron powder data (Rsb(ro) = 6.82, Rsb(psilon) = 4.09). As expected, the X-ray standard deviations of the positional and thermal parameters are smaller than the corresponding neutron standard deviations. However, the dynamical disorder deduced from the anomalously large thermal vibrations of the vanadium atoms obtained from the X-ray data is also evidenced by the neutron refinement. On the other hand, the neutron standard deviations of the lattice parameters are smaller than the X-ray counterparts

  19. Calculation of multigroup constants in WIMS format with programs fedgroup and flange and comparison of the results obtained using different evaluated libraries

    International Nuclear Information System (INIS)

    Trkov, A.; Budnar, M.; Copic, M.; Perdan, A.; Ravnik, M.

    1982-01-01

    Multigroup constants for 1-H-1, 92-U-235, and 92-U-238 have been calculated. Averaged cross-sections and other constants have been prepared in the WIMS 69-group format. Comparison has been made between group constants obtained with several evaluated libraries (KEDAK-3 1975, 1979, ENDF/B-4, ENDF/B-5) and the WIMS-D library. Observed differences are most pronounced in the resonance and fast region. From test runs on fuel cell with the WIMS program it can be deduced that these differences affect the fewgroup constants significantly. (author)

  20. Barriers to Point-of-Care Testing in India: Results from Qualitative Research across Different Settings, Users and Major Diseases

    Science.gov (United States)

    Engel, Nora; Ganesh, Gayatri; Patil, Mamata; Yellappa, Vijayashree; Pant Pai, Nitika; Vadnais, Caroline; Pai, Madhukar

    2015-01-01

    Background Successful point-of-care testing, namely ensuring the completion of the test and treat cycle in the same encounter, has immense potential to reduce diagnostic and treatment delays, and impact patient outcomes. However, having rapid tests is not enough, as many barriers may prevent their successful implementation in point-of-care testing programs. Qualitative research on diagnostic practices may help identify such barriers across different points of care in health systems. Methods In this exploratory qualitative study, we conducted 78 semi-structured interviews and 13 focus group discussions in an urban and rural area of Karnataka, India, with healthcare providers (doctors, nurses, specialists, traditional healers, and informal providers), patients, community health workers, test manufacturers, laboratory technicians, program managers and policy-makers. Participants were purposively sampled to represent settings of hospitals, peripheral labs, clinics, communities and homes, in both the public and private sectors. Results In the Indian context, the onus is on the patient to ensure successful point-of-care testing across homes, clinics, labs and hospitals, amidst uncoordinated providers with divergent and often competing practices, in settings lacking material, money and human resources. We identified three overarching themes affecting point-of-care testing: the main theme is ‘relationships’ among providers and between providers and patients, influenced by the cross-cutting theme of ‘infrastructure’. Challenges with both result in ‘modified practices’ often favouring empirical (symptomatic) treatment over treatment guided by testing. Conclusions Even if tests can be conducted on the spot and infrastructure challenges have been resolved, relationships among providers and between patients and providers are crucial for successful point-of-care testing. Furthermore, these barriers do not act in isolation, but are interlinked and need to be examined

  1. Results of regular study on radionuclidic purity of sup(99m)Tc obtained from 99Mo-sup(99m)Tc generators

    International Nuclear Information System (INIS)

    Vlcek, J.; Rohacek, J.; Husak, V.

    1979-01-01

    A total of 39 sup(99m)Tc eluates obtained from 9 99 Mo-sup(99m)Tc generators delivered by The Radiochemical Centre Amersham during one year was studied with regard to their radionuclide purity. Using a Ge(Li) spectrometer the contaminants 60 Co, 103 Ru, 131 I, 134 Cs, 140 La and 188 Re were found in sup(99m)Tc-eluates with average levels ranging from 2.9 x 10 -3 to 2.8 x 10 -1 per cent of sup(99m)Tc activity. The additional total body absorbed dose caused by these contaminants, as calculated from their average content in sup(99m)Tc eluates, was less than 1% of the dose due to sup(99m)Tc pertechnetate. (orig.) 891 MG/orig. 892 CS [de

  2. From global to local statistical shape priors novel methods to obtain accurate reconstruction results with a limited amount of training shapes

    CERN Document Server

    Last, Carsten

    2017-01-01

    This book proposes a new approach to handle the problem of limited training data. Common approaches to cope with this problem are to model the shape variability independently across predefined segments or to allow artificial shape variations that cannot be explained through the training data, both of which have their drawbacks. The approach presented uses a local shape prior in each element of the underlying data domain and couples all local shape priors via smoothness constraints. The book provides a sound mathematical foundation in order to embed this new shape prior formulation into the well-known variational image segmentation framework. The new segmentation approach so obtained allows accurate reconstruction of even complex object classes with only a few training shapes at hand.

  3. Comparison of ATLAS Tilecal MODULE No 8 high-precision metrology measurement results obtained by laser (JINR) and photogrammetric (CERN) methods

    CERN Document Server

    Batusov, V; Gayde, J C; Khubua, J I; Lasseur, C; Lyablin, M V; Miralles-Verge, L; Nessi, Marzio; Rusakovitch, N A; Sissakian, A N; Topilin, N D

    2002-01-01

    The high-precision assembly of large experimental set-ups is of a principal necessity for the successful execution of the forthcoming LHC research programme in the TeV-beams. The creation of an adequate survey and control metrology method is an essential part of the detector construction scenario. This work contains the dimension measurement data for ATLAS hadron calorimeter MODULE No. 8 (6 m, 22 tons) which were obtained by laser and by photogrammetry methods. The comparative data analysis demonstrates the measurements agreement within +or-70 mu m. It means, these two clearly independent methods can be combined and lead to the rise of a new-generation engineering culture: high-precision metrology when precision assembling of large scale massive objects. (3 refs).

  4. Comparison of ATLAS tilecal module No. 8 high-precision metrology measurement results obtained by laser (JINR) and photogrammetric (CERN) methods

    International Nuclear Information System (INIS)

    Batusov, V.; Budagov, Yu.; Gayde, J.C.

    2002-01-01

    The high-precision assembly of large experimental set-ups is of a principal necessity for the successful execution of the forthcoming LHC research programme in the TeV-beams. The creation of an adequate survey and control metrology method is an essential part of the detector construction scenario. This work contains the dimension measurement data for ATLAS hadron calorimeter MODULE No. 8 (6 m, 22 tons) which were obtained by laser and by photogrammetry methods. The comparative data analysis demonstrates the measurements agreement within ± 70 μm. It means, these two clearly independent methods can be combined and lead to the rise of a new-generation engineering culture: high-precision metrology when precision assembling of large scale massive objects

  5. Recovery potential of a western lowland gorilla population following a major Ebola outbreak: results from a ten year study.

    Science.gov (United States)

    Genton, Céline; Cristescu, Romane; Gatti, Sylvain; Levréro, Florence; Bigot, Elodie; Caillaud, Damien; Pierre, Jean-Sébastien; Ménard, Nelly

    2012-01-01

    Investigating the recovery capacity of wildlife populations following demographic crashes is of great interest to ecologists and conservationists. Opportunities to study these aspects are rare due to the difficulty of monitoring populations both before and after a demographic crash. Ebola outbreaks in central Africa have killed up to 95% of the individuals in affected western lowland gorilla (Gorilla gorilla gorilla) populations. Assessing whether and how fast affected populations recover is essential for the conservation of this critically endangered taxon. The gorilla population visiting Lokoué forest clearing, Odzala-Kokoua National Park, Republic of the Congo, has been monitored before, two years after and six years after Ebola affected it in 2004. This allowed us to describe Ebola's short-term and long-term impacts on the structure of the population. The size of the population, which included around 380 gorillas before the Ebola outbreak, dropped to less than 40 individuals after the outbreak. It then remained stable for six years after the outbreak. However, the demographic structure of this small population has significantly changed. Although several solitary males have disappeared, the immigration of adult females, the formation of new breeding groups, and several birth events suggest that the population is showing potential to recover. During the outbreak, surviving adult and subadult females joined old solitary silverbacks. Those females were subsequently observed joining young silverbacks, forming new breeding groups where they later gave birth. Interestingly, some females were observed joining silverbacks that were unlikely to have sired their infant, but no infanticide was observed. The consequences of the Ebola outbreak on the population structure were different two years and six years after the outbreak. Therefore, our results could be used as demographic indicators to detect and date outbreaks that have happened in other, non-monitored gorilla

  6. Barriers to Point-of-Care Testing in India: Results from Qualitative Research across Different Settings, Users and Major Diseases.

    Directory of Open Access Journals (Sweden)

    Nora Engel

    Full Text Available Successful point-of-care testing, namely ensuring the completion of the test and treat cycle in the same encounter, has immense potential to reduce diagnostic and treatment delays, and impact patient outcomes. However, having rapid tests is not enough, as many barriers may prevent their successful implementation in point-of-care testing programs. Qualitative research on diagnostic practices may help identify such barriers across different points of care in health systems.In this exploratory qualitative study, we conducted 78 semi-structured interviews and 13 focus group discussions in an urban and rural area of Karnataka, India, with healthcare providers (doctors, nurses, specialists, traditional healers, and informal providers, patients, community health workers, test manufacturers, laboratory technicians, program managers and policy-makers. Participants were purposively sampled to represent settings of hospitals, peripheral labs, clinics, communities and homes, in both the public and private sectors.In the Indian context, the onus is on the patient to ensure successful point-of-care testing across homes, clinics, labs and hospitals, amidst uncoordinated providers with divergent and often competing practices, in settings lacking material, money and human resources. We identified three overarching themes affecting point-of-care testing: the main theme is 'relationships' among providers and between providers and patients, influenced by the cross-cutting theme of 'infrastructure'. Challenges with both result in 'modified practices' often favouring empirical (symptomatic treatment over treatment guided by testing.Even if tests can be conducted on the spot and infrastructure challenges have been resolved, relationships among providers and between patients and providers are crucial for successful point-of-care testing. Furthermore, these barriers do not act in isolation, but are interlinked and need to be examined as such. Also, a test alone has only

  7. Recovery potential of a western lowland gorilla population following a major Ebola outbreak: results from a ten year study.

    Directory of Open Access Journals (Sweden)

    Céline Genton

    Full Text Available Investigating the recovery capacity of wildlife populations following demographic crashes is of great interest to ecologists and conservationists. Opportunities to study these aspects are rare due to the difficulty of monitoring populations both before and after a demographic crash. Ebola outbreaks in central Africa have killed up to 95% of the individuals in affected western lowland gorilla (Gorilla gorilla gorilla populations. Assessing whether and how fast affected populations recover is essential for the conservation of this critically endangered taxon. The gorilla population visiting Lokoué forest clearing, Odzala-Kokoua National Park, Republic of the Congo, has been monitored before, two years after and six years after Ebola affected it in 2004. This allowed us to describe Ebola's short-term and long-term impacts on the structure of the population. The size of the population, which included around 380 gorillas before the Ebola outbreak, dropped to less than 40 individuals after the outbreak. It then remained stable for six years after the outbreak. However, the demographic structure of this small population has significantly changed. Although several solitary males have disappeared, the immigration of adult females, the formation of new breeding groups, and several birth events suggest that the population is showing potential to recover. During the outbreak, surviving adult and subadult females joined old solitary silverbacks. Those females were subsequently observed joining young silverbacks, forming new breeding groups where they later gave birth. Interestingly, some females were observed joining silverbacks that were unlikely to have sired their infant, but no infanticide was observed. The consequences of the Ebola outbreak on the population structure were different two years and six years after the outbreak. Therefore, our results could be used as demographic indicators to detect and date outbreaks that have happened in other, non

  8. Microseismicity along major Ross Ice Shelf rift resulting from thermal contraction of the near-surface firn layer

    Science.gov (United States)

    Olinger, S.; Wiens, D.; Aster, R. C.; Bromirski, P. D.; Gerstoft, P.; Nyblade, A.; Stephen, R. A.

    2017-12-01

    Seismicity within ice shelves arises from a variety of sources, including calving, rifting, and movement along internal discontinuities. In this study, we identify and locate cryoseisms in the Ross Ice Shelf (RIS) to better understand ice shelf internal stress and deformation. We use data from a two-year 34-station deployment of broadband seismographs operational from December 2014 - November 2016. Two lines of seismographs intersect near 79Sº, 180º close to a large rift, and cryoseisms were recorded by up to 10 seismographs within 40 km of the rift tip. We identified 3600 events from 2015 and grouped them by quality based on the number of stations recording and signal-to-noise ratio. The events show a long-period character compared to similar magnitude tectonic earthquakes, with peak amplitudes at 1-4 Hz and P, S, longitudinal, and surface wave arrivals. Cross correlation analysis shows that the events cannot be divided into a small number of repeating event clusters with identical waveforms. 262 A-quality events were located with a least-squares algorithm using P and S arrivals, and the resulting locations show strong spatial correlation with the rift, with events distributed along the rift rather than concentrated at the tip or any other specific feature. The events do not show teleseismic triggering, and did not occur with increased frequency following the Illapel earthquake (8.3 Mw) or subsequent tsunami. Instead, we note a concentration of activity during the winter months, with several days exhibiting particularly high seismicity rates. We compare the full catalog of events with temperature data from the Antarctic Weather Stations (Lazzara et al, 2012) and find that the largest swarms occur during the most rapid periods of seasonal temperature decline. Internal stress in ice floes and shelves is known to vary with air temperature; as temperature drops, the upper layer of ice thermally contracts, causing near-surface extensional stress to accumulate. We

  9. [Management strategies for major depressive episodes as a function of initial response to an SSRI or SNRI antidepressant: results of the ORACLE survey].

    Science.gov (United States)

    Spadone, C; Sylvestre, M; Chiarelli, P; Richard-Berthe, C

    2005-01-01

    The main aim of the major depressive episode treatment is to obtain a complete remission. However, partial remission (persistence of residual symptoms) is a frequent outcome of major depressive episodes, concerning approximately half of the patients who were responders to the treatment. An inadequate treatment response after three weeks of treatment is considered by the ANAES recommendations as a potential reason to modify the treatment regimen. The primary objectives of this survey were to describe the therapeutic strategies implemented in subjects treated as outpatients for a major depressive episode following evaluation of the initial response to an SSRI or an SNRI antidepressant and to assess by a naturalistic way the impact of these strategies on the extent of remission at three months. The secondary objective was to determine, by multivariate analysis, others factors able to influence the remission. This prospective observational survey concerned 2 138 patients treated by community psychiatrists (n=582) and presenting a major depressive episode in the context of a recurrent depressive disorder. Patients were assessed at inclusion and at Weeks 3, at Week 6 and at Week 12. Changes in score on the Hamilton Depression Scale (Ham-D) and CGI severity between inclusion and Week 3 and improvement scores were evaluated. The therapeutic strategies after evaluation were described. Remission was defined as a score of 1 or 2 on the CGI-improvement scale; a treatment response at Week 3 was defined as a decrease of at least 50% in the Ham-D score. The physician also provided an overall rating of satisfaction with the treatment at Week 3. Data from 1 974 patients were analysed. The mean age at inclusion was 42.7 years, 70% of the patients were women; the mean age at first episode was 32.2 years, the average time since the last episode was 3.6 years. The mean Ham-D score at inclusion was 23.6 +/- 5.8. At Week 3, 29.1% of patients were considered treatment responders. The

  10. results of Breeding Tomato Programme (lycopesicon esculentum mill) for the obtaining of new Tolerant varieties to low inputs hidric through the employment of the Radioinduced mutation

    International Nuclear Information System (INIS)

    Gonzalez, Maria C.; Caballero, Alberto; Mukandama, Jean Pierre; Mohamed Ali, Mansoor; Suarez, Lorenzo; Fuentes, Jorge L

    1999-01-01

    Induced mutation have been mostly used in the improvement of different crops. This papers shows the main results of Breeding Tomato Programme. It was possible to select some promising lines with a good behavior under hidric stress

  11. Final results of the cadmium and spectral ratios obtained inside of the fuel rod positioned in the central position of the IPEN/MB-01 nuclear reactor

    Energy Technology Data Exchange (ETDEWEB)

    Bitelli, Ulysses d' Utra; Mura, Luiz Ernesto C.; Santos, Diogo Feliciano dos, E-mail: ubitelli@ipen.br [Instituto de Pesquisas Energeticas e Nucleares (IPEN/CNEN-SP), Sao Paulo, SP (Brazil); Lambiasi, Beatriz G.N. [Centro Tecnologico da Marinha em Sao Paulo (CTMSP), SP (Brazil)

    2015-07-01

    The spectral ratios are very important to determine some nuclear reactors parameters such as reaction rates, fuel lifetime, etc and some safety operational conditions. This study aims to determine the spectral ratios in 2 (two) spatial positions located inside the core of the Nuclear Reactor IPEN/MB-01. These places are at the central position of the nuclear reactor core in an asymptotic neutron flux region. The experiment consists in inserting different activation foil detectors inside an experimental fuel rod. The experimental rod is assembled at the central position of the reactor core. Activation neutron foil detectors of different elements such as {sup 197}Au, {sup 238}U, {sup 45}Sc, {sup 58}Ni, {sup 24}Mg, {sup 47}Ti and {sup 115m}In were used to cover a large range of neutron spectrum. Saturation activity per target nucleus was obtained by gamma spectrometry using a HPGe system. The experimental cadmium ratios compared with values computed by MCNP-4C code show good agreement. (author)

  12. Results and interpretation of groundwater data obtained from multiport-instrumented coreholes (GW-131 through GS-135), fiscal years 1990 and 1991

    International Nuclear Information System (INIS)

    Dreier, R.B.; Early, T.O.; King, H.L.

    1993-01-01

    With the increased emphasis by Department of Energy personnel on assessing the environmental impact of past waste disposal practices at all of its facilities, there has been an associated increase in characterization activities that focus on delineating site-specific groundwater flow regimes and contaminant migration pathways. At the Oak Ridge Y-12 Plant, the complex geologic and hydrologic relationships require a more detailed understanding of the three-dimensional properties of groundwater flow regimes than can be obtained by conventional monitoring activities. Thus, as part of groundwater characterization activities conducted by the Environmental Surveillance Section staff of the Y-12 Plant Environmental Management Department, five existing deep core holes were instrumented with multiport monitoring systems to provide greatly enhanced resolution of the hydraulic and hydrochemical properties of the groundwater system within Bear Creek Valley. With a multiport system, it is possible to measure hydraulic head and hydraulic conductivity and collect water samples from multiple levels within a single borehole. In this report, multiport data collected during fiscal years (FYs) 1990 and 1991 are summarized

  13. Results obtained in a spectrometry using junction detectors (1962); Resultats en spectrometrie {alpha} a l'aide de ''detecteurs jonction'' (1962)

    Energy Technology Data Exchange (ETDEWEB)

    Beaumevieille, H; Fontenille, J; Lottgequeue, J P; Longequeue, N; Rabour, C [Commissariat a l' Energie Atomique, Grenoble (France). Centre d' Etudes Nucleaires

    1962-07-01

    Junction detectors have been used for studying {alpha} spectra obtained by nuclear reactions (p, {alpha}), the protons being produced by an electrostatic accelerator (E{sub p} varying from 100 to 600 keV). Difficulties have been encountered arising from parasitic noise from the accelerator and from the distance (60 metres) between detectors and electronic equipment. Resolution of the counter has been found to be 0.6 per cent with {alpha} from {sup 210}Po and 1.2 pour cent with {alpha} (5.8 MeV) from the reaction {sup 11}B (p, {alpha}{sub 0}). (authors) [French] Des detecteurs a jonction ont ete utilises pour l'etude de spectres {alpha} obtenus par reactions nucleaires (p, {alpha}), les protons etant acceleres par un accelerateur electrostatique (E{sub p} variant de 100 a 600 keV). Des difficultes ont ete recontrees dues aux parasites provenant de l'accelerateur et a la distance des cables (60 metres) entre detecteurs et appareils de mesure. Le pouvoir de resolution de l'ensemble a ete de 0, 6 pour cent avec les {alpha} du {sup 210}Po et de 1,2 pour cent avec les {alpha} (5,8 MeV) de la reaction {sup 11}B (p, {alpha}{sub 0}). (auteurs)

  14. Preliminary Results Obtained from Flight Test of a Rocket Model Having the Tail Only of the Grumman XF10F Airplane Configuration, TED No. NACA DE 354

    Science.gov (United States)

    Gardner, William N.; Edmondson, James L.

    1950-01-01

    A flight test was made to determine the servoplane effectiveness and stability characteristics of the free-floating horizontal stabilizer to be used on the XF10F airplane. The results of this test indicate that servoplane effectiveness is practically constant through the speed range up to a Mach number of 1.15, and the stabilizer static stability is satisfactory. A loss of damping occurs over a narrow Mach number range near M = 1.0, resulting in dynamic instability of the stabilizer in this narrow range. Above M = 1.0 there is a gradual positive trim change of the stabilizer.

  15. A comparison of texture results obtained using precession electron diffraction and neutron diffraction methods at diminishing length scales in ordered bimetallic nanolamellar composites

    International Nuclear Information System (INIS)

    Carpenter, J.S.; Liu, X.; Darbal, A.; Nuhfer, N.T.; McCabe, R.J.; Vogel, S.C.; LeDonne, J.E.; Rollett, A.D.; Barmak, K.; Beyerlein, I.J.; Mara, N.A.

    2012-01-01

    Precession electron diffraction (PED) is used to acquire orientation information in Cu–Nb nanolamellar composites fabricated by accumulative roll bonding (ARB). The resulting maps quantify the grain size, shape, orientation distributions and interface planes in the vicinity of nanometer-thick deformation twins. The PED-based texture results compare favorably with bulk textures provided by neutron diffraction measurements, indicating uniformity in the ARB Cu–Nb texture. Additionally, {1 1 2} Cu ||{1 1 2} Nb interfaces are present, suggesting that ARB techniques can lead to stable interfaces with a special crystallography.

  16. A comparison of the impact of screen-positive results obtained from ultrasound and biochemical screening for Down syndrome in the first trimester : a pilot study

    NARCIS (Netherlands)

    Weinans, M.J.; Kooij, L.; Muller, M.A.; Bilardo, K.M.; van Lith, J.M.; Tymstra, T.

    2004-01-01

    OBJECTIVE: To compare the experiences of women who received a screen-positive test result for Down syndrome after nuchal translucency screening or after biochemical screening in the first trimester of pregnancy in the Netherlands. METHOD: Semi-quantitative questionnaires were sent to 40 women with a

  17. Comparison of stapes prostheses: a retrospective analysis of individual audiometric results obtained after stapedotomy by implantation of a gold and a teflon piston

    NARCIS (Netherlands)

    de Bruijn, A. J.; Tange, R. A.; Dreschler, W. A.

    1999-01-01

    PURPOSE: Evaluation of hearing results after implantation of a Teflon piston (type Causse; Xomed Surgical Products, Jacksonville, FL) and of a pure gold piston (K-piston; Heinz Kurz GmbH Medizintechnik, Dusslingen, Germany), both with a shaft diameter of 0.4 mm in cases of otosclerosis requiring

  18. A retrospective study of the hearing results obtained after stapedotomy by the implantation of two Teflon pistons with a different diameter

    NARCIS (Netherlands)

    Grolman, W.; Tange, R. A.; de Bruijn, A. J.; Hart, A. A.; Schouwenburg, P. F.

    1997-01-01

    This study reports the evaluation of hearing results after implantation of a Teflon piston of a different diameter in cases of otosclerosis requiring stapedotomy. By random selection, a Teflon piston with a shaft diameter of 0.3 mm was inserted in 34 cases and a piston with a shaft diameter of 0.4

  19. Compatibility study of the different pole figures in one and the same specimen. Comparison between the results obtained by neutron and by X-ray diffraction

    International Nuclear Information System (INIS)

    Pernot, M.; Penelle, R.; Dervin, P.

    1981-01-01

    Development of a calculation to show directly the compatibility of the different pole figures in the same specimen is exposed. A review of the method by serial development is given. Experimental methods are described. The position of the anisotropy axes is determined. Compatibilities resulting from X-ray and from neutron diffraction is analysed [fr

  20. Assessing representativeness of sampling methods for reaching men who have sex with men: a direct comparison of results obtained from convenience and probability samples.

    Science.gov (United States)

    Schwarcz, Sandra; Spindler, Hilary; Scheer, Susan; Valleroy, Linda; Lansky, Amy

    2007-07-01

    Convenience samples are used to determine HIV-related behaviors among men who have sex with men (MSM) without measuring the extent to which the results are representative of the broader MSM population. We compared results from a cross-sectional survey of MSM recruited from gay bars between June and October 2001 to a random digit dial telephone survey conducted between June 2002 and January 2003. The men in the probability sample were older, better educated, and had higher incomes than men in the convenience sample, the convenience sample enrolled more employed men and men of color. Substance use around the time of sex was higher in the convenience sample but other sexual behaviors were similar. HIV testing was common among men in both samples. Periodic validation, through comparison of data collected by different sampling methods, may be useful when relying on survey data for program and policy development.

  1. Development of integrated system of spatial coordinates for inputting cartographic information obtained as result of scientific researches at exclusion zone area

    International Nuclear Information System (INIS)

    Mazur, A.B.; Ermolenko, A.I.; Shaptala, D.V.; Postil, S.D.; Yachmenev, V.V.

    1999-01-01

    Integrated system of spatial coordinates was developed for modeling of diverse processes occurring in the exclusion zone. Technology of joint use of CAD and geoinformation system was worked out,which resulted in the 'Ukryttia' object fixing to the topographic base in accordance with geographic coordinates, editing of nomenclative sheets of the area adjacent to the ChNPP and renovation of its relief, as well as conversion of the files made in AutoCad to Arc View format files was performed

  2. Technique to Obtain a Predictable Aesthetic Result through Appropriate Placement of the Prosthesis/Soft Tissue Junction in the Edentulous Patient with a Gingival Smile.

    Science.gov (United States)

    Demurashvili, Georgy; Davarpanah, Keyvan; Szmukler-Moncler, Serge; Davarpanah, Mithridade; Raux, Didier; Capelle-Ouadah, Nedjoua; Rajzbaum, Philippe

    2015-10-01

    Treating the edentulous patient with a gingival smile requires securing the prosthesis/soft tissue junction (PSTJ) under the upper lip. To present a simple method that helps achieve a predictable aesthetic result when alveoplasty of the anterior maxilla is needed to place implants apical to the presurgical position of the alveolar ridge. The maximum smile line of the patient is recorded and carved on a thin silicone bite impression as a soft tissue landmark. During the three-dimensional radiographic examination, the patient wears the silicone guide loaded with radiopaque markers. The NobelClinician® software is then used to bring the hard and soft tissue landmarks together in a single reading. Using the software, a line is drawn 5 mm apical to the smile line; it dictates the position of the crestal ridge to be reached following the alveoplasty. Subsequently, the simulated implant position and the simulated residual bone height following alveoplasty can be simultaneously evaluated on each transverse section. An alveoplasty of the anterior maxilla was performed as simulated on the software, and implants were placed accordingly. The PSTJ was always under the upper lip, even during maximum smile events. The aesthetic result was, therefore, fully satisfactory. This simple method permits the placement of the PSTJ under the upper lip with a predictable outcome; it ensures a reliable aesthetic result for the edentulous patient with a gingival smile. © 2013 Wiley Periodicals, Inc.

  3. A feasibility study of prepubertal and over mature aged local goat in relation to results of In Vitro growth culture to obtain additional M-II oocyte resources

    Science.gov (United States)

    Ciptadi, Gatot; Ihsan, M. Nur; Rahayu, Sri; Widjaja, D. H. K.; Mudawamah, Mudawamah

    2017-11-01

    The aims of this research are to study the potential source of mature (M-II) oocytes of domestic animals using follicles isolated from prepubertal and over mature aged Indonesian local goats, resulting from an in vitro growth (IVG) method. This method of IVG could provide a new source of M-II oocytes for embryo production. In Indonesia, a very limited number of a good quality oocytes are available for research purposes, as there is a limited number of reproductive females slaughtered, which is dominated by prepubertal and old mature aged animals. IVG culture systems could be improved as an alternative method to provide a new source of a good quality oocytes for in vitro maturation of M-II oocytes. From a number of prepubertal and mature aged goats slaughtered in a local abattoir, the small oocytes in the preantral follicles were cultured in vitro to normal oocyte growth. The methods used in this research are experimental. Follicles were isolated, cultured in vitro for 14 days individually using a sticky medium containing 4% (w/v) polyvinylpyrrolidone in TCM 199 10% Fetal Bovine Serum supplemented with Follicle Stimulating Hormone, which was then evaluated for their follicle development and oocyte quality. The research results showed that a minimum follicle size and oocyte diameter is needed (>100 um) for early evaluation of maturation to be achieved, meanwhile oocytes recovered from IVG after being cultured in vitro for maturation resulted in a very low rate of maturation. However, in the future, IVG of the preantral follicles of Indonesian local goat could be considered as an alternative source of oocytes for both research purposes and embryo production in vitro.

  4. Contribution to a summary of the results obtained in the field of geology on the Oklo natural reactors and their environment

    International Nuclear Information System (INIS)

    Weber, F.

    1978-01-01

    The very special characteristics of the ore in the reaction zones may be attributed to the effects of the nuclear reactions themselves: de-structuration of the gangue by neutronic effects and hydrothermal leaching due to the generation of a true thermal syphon by the nuclear reactions. This mechanism contributes to the propagation of reactions from a number of initial reaction sites. The latter were initiated in certain parts of the deposit, enriched as a result of a tectonic episode, by oxidizing currents in the shear troughs. These enriched zones occur as anomalies within a pre-existent deposit, the formation of which still poses many questions of a metallogenic nature. (author)

  5. A nonparametric statistical method for determination of a confidence interval for the mean of a set of results obtained in a laboratory intercomparison

    International Nuclear Information System (INIS)

    Veglia, A.

    1981-08-01

    In cases where sets of data are obviously not normally distributed, the application of a nonparametric method for the estimation of a confidence interval for the mean seems to be more suitable than some other methods because such a method requires few assumptions about the population of data. A two-step statistical method is proposed which can be applied to any set of analytical results: elimination of outliers by a nonparametric method based on Tchebycheff's inequality, and determination of a confidence interval for the mean by a non-parametric method based on binominal distribution. The method is appropriate only for samples of size n>=10

  6. A cross-cultural study on noise problems: Comparison of the results obtained in Japan, West Germany, the U.S.A., China and Turkey

    Science.gov (United States)

    Namba, S.; Kuwano, S.; Schick, A.; Açlar, A.; Florentine, M.; Da Rui, Zheng

    1991-12-01

    Neighborhood noise has become a serious problem in many countries, and it is difficult to regulate by physical means alone. A cross-cultural survey was conducted in five countries, Japan, West Germany, the United States, China and Turkey, among residents of apartment houses in order to examine the cultural differences involved. Interesting differences were found in preferred countermeasures, highly annoying sounds, attitudes against noise, expectations for laws, etc. The use of loudspeakers in public places was accepted in all five countries, provided that they were used for conveying necessary information. The results suggest that it is important to take cultural or social backgrounds into consideration in order to find suitable countermeasures.

  7. Reducing the item number to obtain the same-length self-assessment scales: a systematic approach using result of graphical loglinear rasch models

    DEFF Research Database (Denmark)

    Nielsen, Tine; Kreiner, Svend

    2011-01-01

    The Revised Danish Learning Styles Inventory (R-D-LSI) (Nielsen 2005), which is an adaptation of Sternberg- Wagner Thinking Styles Inventory (Sternberg, 1997), comprises 14 subscales, each measuring a separate learning style. Of these 14 subscales, 9 are eight items long and 5 are seven items long...... Inventory (D-SA-LSI) comprising 14 subscales each with an item length of seven. The systematic approach to item reduction based on results of GLLRM will be presented and exemplified by its application to the R-D-LSI....

  8. On the Evaluation of Computational Results Obtained from Solving System of linear Equations With matlab The Dual affine Scalling interior Point

    International Nuclear Information System (INIS)

    Murfi, Hendri; Basaruddin, T.

    2001-01-01

    The interior point method for linear programming has gained extraordinary interest as an alternative to simplex method since Karmarkar presented a polynomial-time algorithm for linear programming based on interior point method. In implementation of the algorithm of this method, there are two important things that have impact heavily to performance of the algorithm; they are data structure and used method to solve linear equation system in the algorithm. This paper describes about solving linear equation system in variants of the algorithm called dual-affine scaling algorithm. Next, we evaluate experimentally results of some used methods, either direct method or iterative method. The experimental evaluation used Matlab

  9. Contribution to an understanding of the action of gamma radiation on granular starch - interpretation of results obtained using the enzymatic and chromatographic method

    International Nuclear Information System (INIS)

    Robin, J.P.; Tollier, M.Th.; Guilbot, A.

    1978-01-01

    Besides compounds of low molecular mass, the gamma irradiation of granular starch produces radiodextrins with a mass lying between that of the low-molecular-mass compounds and that of the amylose and amylopectin macromolecules from which they derive. The authors present the main results relating to characterization of the radiodextrins of strongly irradiated relating to characterization of the radiodextrins of strongly irradiated normal and waxy maize starches. The method of study - both enzymatic and chromatographic - is the one that has been in use for some ten years for studying the fine structure of α-1.4-1.6 glucanes. An attempt is made to interpret and integrate the results in the light of new data derived from a study of the controlled acid hydrolysis of starch. In particular, the following hypothesis is advanced: the 'hydrolytic' effect of irradiation is, at the qualitative level, independent of the nature of the starch and similar to the effect produced by acid hydrolysis; as with acid hydrolysis, the breaking of the covalent bonds is a function of the internal strucutre of the grain and especially of its amorphous/crystalline organization; the zones of an amorphous character are more easily degraded; on the other hand, the 'crystalline' zones are better protected; in fact, the 'hydrolytic' effect of irradiation is not homogeneous and does not conform to a statistical pattern. (author)

  10. The contribution of an asthma diagnostic consultation service in obtaining an accurate asthma diagnosis for primary care patients: results of a real-life study.

    Science.gov (United States)

    Gillis, R M E; van Litsenburg, W; van Balkom, R H; Muris, J W; Smeenk, F W

    2017-05-19

    Previous studies showed that general practitioners have problems in diagnosing asthma accurately, resulting in both under and overdiagnosis. To support general practitioners in their diagnostic process, an asthma diagnostic consultation service was set up. We evaluated the performance of this asthma diagnostic consultation service by analysing the (dis)concordance between the general practitioners working hypotheses and the asthma diagnostic consultation service diagnoses and possible consequences this had on the patients' pharmacotherapy. In total 659 patients were included in this study. At this service the patients' medical history was taken and a physical examination and a histamine challenge test were carried out. We compared the general practitioners working hypotheses with the asthma diagnostic consultation service diagnoses and the change in medication that was incurred. In 52% (n = 340) an asthma diagnosis was excluded. The diagnosis was confirmed in 42% (n = 275). Furthermore, chronic rhinitis was diagnosed in 40% (n = 261) of the patients whereas this was noted in 25% (n = 163) by their general practitioner. The adjusted diagnosis resulted in a change of medication for more than half of all patients. In 10% (n = 63) medication was started because of a new asthma diagnosis. The 'one-stop-shop' principle was met with 53% of patients and 91% (n = 599) were referred back to their general practitioner, mostly within 6 months. Only 6% (n = 41) remained under control of the asthma diagnostic consultation service because of severe unstable asthma. In conclusion, the asthma diagnostic consultation service helped general practitioners significantly in setting accurate diagnoses for their patients with an asthma hypothesis. This may contribute to diminish the problem of over and underdiagnosis and may result in more appropriate treatment regimens. SERVICE HELPS GENERAL PRACTITIONERS MAKE ACCURATE DIAGNOSES: A consultation service can

  11. An overview of experimental results obtained under the prestressed concrete nuclear pressure vessel development program at the Oak Ridge National Laboratory

    International Nuclear Information System (INIS)

    Naus, D.J.

    1979-01-01

    Under the Prestressed Concrete Nuclear Pressure Development Program at the Oak Ridge National Laboratory, various aspects of Prestressed Concrete Pressure Vessels (PCPVs) are investigated with respect to reliability, structural performance, constructability, and economy. These investigations are conducted under the High-Temperature Gas-Cooled Reactor (HTGR) Program and the Gas-Cooled Fast Reactor (GCFR) Program. The objectives are to: (1) provide technical support to ongoing PCPV design activities, (2) contribute to the overall technological data base, and (3) provide independent review and evaluations. Specific areas of interest at present include finite-element analysis development, materials and structural behaviour tests, instrumentation evaluations and development, and structural model tests. The following provides an overview of both the HTGR and GCFR PCPV activities and a summary of recent experimental results

  12. Correlation of results obtained by in-vivo optical spectroscopy with measured blood oxygen saturation using a positive linear regression fit

    Science.gov (United States)

    McCormick, Patrick W.; Lewis, Gary D.; Dujovny, Manuel; Ausman, James I.; Stewart, Mick; Widman, Ronald A.

    1992-05-01

    Near infrared light generated by specialized instrumentation was passed through artificially oxygenated human blood during simultaneous sampling by a co-oximeter. Characteristic absorption spectra were analyzed to calculate the ratio of oxygenated to reduced hemoglobin. A positive linear regression fit between diffuse transmission oximetry and measured blood oxygenation over the range 23% to 99% (r2 equals .98, p signal was observed in the patient over time. The procedure was able to be performed clinically without difficulty; rSO2 values recorded continuously demonstrate the usefulness of the technique. Using the same instrumentation, arterial input and cerebral response functions, generated by IV tracer bolus, were deconvoluted to measure mean cerebral transit time. Date collected over time provided a sensitive index of changes in cerebral blood flow as a result of therapeutic maneuvers.

  13. Can Good Infection Control Be Obtained in One-stage Exchange of the Infected TKA to a Rotating Hinge Design? 10-year Results.

    Science.gov (United States)

    Zahar, Akos; Kendoff, Daniel O; Klatte, Till O; Gehrke, Thorsten A

    2016-01-01

    Prosthetic joint infection (PJI) occurs in 1% to 2% of total knee arthroplasties (TKAs). Although two-stage exchange is the preferred management method of patients with chronic PJI in TKA in North America, one-stage exchange is an alternative treatment method, but long-term studies of this approach have not been conducted. We reviewed our minimum 9-year results of 70 patients who underwent one-stage exchange arthroplasty with a rotating hinge design to determine: (1) What was the proportion of patients free of infection? (2) What was the patient rate of survival free of any reoperation? (3) What were the clinical outcomes as measured by Hospital for Special Surgery scores? (4) What proportion of patients developed radiographic evidence of loosening? All one-stage revision TKAs for infection between January 1 and December 31, 2002, with a minimum 9-year followup (mean, 10 years; range, 9-11 years), in which patients had been seen within the last 1 year, were included in this retrospective review. During that period, 11 patients with infected TKAs were treated with other approaches (including two-stage approaches in eight); the general indication for one-stage revision was the diagnosis of PJI with a known causative organism. Exclusion criteria were culture-negative preoperative aspiration, known allergy to local antibiotics or bone cement, or cases in which radical débridement was impossible as a result of the involvement of important anatomical structures. Eighty-one patients with PJI were seen during this period; 70 underwent one-stage exchange using our strict protocol and were reimplanted with a rotating hinge TKA. Eleven patients (15.7%) were lost to followup. Hospital for Special Surgery scores were recorded and all radiographs were evaluated for prosthetic loosening. Failure was defined as revision surgery for infection or any other cause. Our 10-year infection-free survival was 93% (mean, 4.1; 95% confidence interval [CI], 89%-96%; p exchange techniques for

  14. Results of the new processing of images obtained from the surface of Venus in a TV experiment onboard the VENERA-9 lander (1975)

    Science.gov (United States)

    Ksanfomality, L. V.

    2012-09-01

    Data on the results of the analysis of the content of re-processed panorama of the VENERA-9 lander are presented. The panorama was transmitted historically for the first time from the surface of Venus in 1975. The low noise of the VENERA-9 data allowed allocating a large object of an unusual regular structure. Earlier, its fuzzy image was repeatedly cited in the literature being interpreted as a "strange stone". The complex shape and its other features suggest that the object may be a real habitant of the planet. It is not excluded that another similar object observed was damaged during the VENERA-9 landing. From the evidence of its movement and position of some other similar objects it is concluded that because of the limited energy capacity, the physical action of the Venusian fauna may be much slower than that of the Earth fauna. Another question considered is what sources of energy could be used by life in the conditions of the high temperature oxygenless atmosphere of the planet. It is natural to assume that, like on Earth, the Venusian fauna is heterotrophic and should be based on hypothetical flora, using photosynthesis (based on an unknown high temperature biophysical mechanism).

  15. Quantity and quality of black carbon molecular markers as obtained by two chromatographic methods (GC-FID and HPLC-DAD) - How do results compare?

    Science.gov (United States)

    Schneider, M. P. W.; Smittenberg, R. H.; Dittmar, T.; Schmidt, M. W. I.

    2009-04-01

    Chars produced by wildfires are an important source of black carbon (BC) in the environment. After their deposition on the soil surface they can be distributed into rivers, marine waters and sediments. The analysis of benzenepolycarboxylic acids (BPCAs) as a quantitative measure for black carbon (BC) in soil and sediment samples is a well-established method (Glaser et al., 1998; Brodowski et al., 2005). Briefly, the nitric acid oxidation of fused aromatic ring systems in BC forms eight molecular markers (BPCAs), which can be assigned to BC, and which subsequently can be quantified by GC-FID (gas chromatography with flame ionization detector). Recently, this method was modified for the quantification of BC in seawater samples using HPLC-DAD (High performance liquid chromatography with diode array detector) for the determination of individual BPCAs (Dittmar, 2008). A direct comparison of both analytical techniques is lacking but would be important for future data comparison aimed at the calculation of global BC budgets. Here we present a systematic comparison of the two BPCA quantification methods. We prepared chars under well-defined laboratory conditions. In order to cover a broad spectrum of char properties we used two sources of biomass and a wide range of pyrolysis temperatures. Chestnut hardwood chips (Castanea sativa) and rice straw (Oryza sativa) were pyrolysed at temperatures between 200 and 1000°C under a constant N2 stream. The maximum temperatures were held constant for 5 hours (Hammes et al., 2006). The BC contents of the chars have been analysed using the BPCA extraction method followed by either GC-FID or HPLC-DAD quantification. Preliminary results suggest that both methods yield similar total quantities of BPCA, and also the proportions of the individual markers are similar. Ongoing experiments will allow for a more detailed comparison of the two methods. The BPCA composition of chars formed at different temperatures and from different precursor

  16. Colorectal endoscopic submucosal dissection (ESD) in the West - when can satisfactory results be obtained? A single-operator learning curve analysis.

    Science.gov (United States)

    Spychalski, Michał; Skulimowski, Aleksander; Dziki, Adam; Saito, Yutaka

    2017-12-01

    Up to date we lack a detailed description of the colorectal endoscopic submucosal dissection (ESD) learning curve, that would represent the experience of the Western center. The aim of this study was to define the critical points of the learning curve and to draw up lesions qualification guidelines tailored to the endoscopists experience. We have carried out a single center prospective study. Between June 2013 and December 2016, 228 primary colorectal lesions were managed by ESD procedure. In order to create a learning curve model and to carry out the analysis the cases were divided into six periods, each consisting of 38 cases. The overall en bloc resection rate was 79.39%. The lowest en bloc resection rate (52.36%) was observed in the first period. After completing 76 procedures, the resection rate surged to 86% and it was accompanied by the significant increase in the mean procedure speed of ≥9 cm 2 /h. Lesions localization and diameter had a signification impact on the outcomes. After 76 procedures, en bloc resection rate of 90.9 and 90.67% were achieved for the left side of colon and rectum, respectively. In the right side of colon statistically significant lower resection rate of 67.57% was observed. We have proved that in the setting of the Western center, colorectal ESD can yield excellent results. It seems that the key to the success during the learning period is 'tailoring' lesions qualification guidelines to the experience of the endoscopist, as lesions diameter and localization highly influence the outcomes.

  17. Is the resulting phenotype of an embryo with balanced X-autosome translocation, obtained by means of preimplantation genetic diagnosis, linked to the X inactivation pattern?

    Science.gov (United States)

    Ferfouri, Fatma; Bernicot, Izabel; Schneider, Anouck; Haquet, Emmanuelle; Hédon, Bernard; Anahory, Tal

    2016-04-01

    To examine if a balanced female embryo with X-autosome translocation could, during its subsequent development, express an abnormal phenotype. Preimplantation genetic diagnosis (PGD) analysis on two female carriers with maternal inherited X-autosome translocations. Infertility center and genetic laboratory in a public hospital. Two female patients carriers undergoing PGD for a balanced X-autosome translocations: patient 1 with 46,X,t(X;2)(q27;p15) and patient 2 with 46,X,t(X;22)(q28;q12.3). PGD for balanced X-autosome translocations. PGD outcomes, fluorescence in situ hybridization in biopsied embryos and meiotic segregation patterns analysis of embryos providing from X-autosome translocation carriers. Controlled ovarian stimulation facilitated retrieval of a correct number of oocytes. One balanced embryo per patient was transferred and one developed, but the patient miscarried after 6 weeks of amenorrhea. In X-autosome translocation carriers, balanced Y-bearing embryos are most often phenotypically normal and viable. An ambiguous phenotype exists in balanced X-bearing embryos owing to the X inactivation mechanism. In 46,XX embryos issued from an alternate segregation, der(X) may be inactivated and partially spread transcriptional silencing into a translocated autosomal segment. Thus, the structural unbalanced genotype could be turned into a viable functional balanced one. It is relevant that a discontinuous silencing is observed with a partial and unpredictable inactivation of autosomal regions. Consequently, the resulting phenotype remains a mystery and is considered to be at risk of being an abnormal phenotype in the field of PGD. It is necessary to be cautious regarding to PGD management for this type of translocation, particularly in transferred female embryos. Copyright © 2016 American Society for Reproductive Medicine. Published by Elsevier Inc. All rights reserved.

  18. Comparative analysis of the long-term results of treatment in patients with Stages I-IIa breast cancer in relation to major prognostic factors

    Directory of Open Access Journals (Sweden)

    Yu. V. Efimkina

    2010-01-01

    Full Text Available The analysis of the long-term results of treatment in patients with Stages I-IIa breast cancer in relation to major prognostic factors re- vealed poor morphological factors that greatly influenced the lifespan of female patients, such as tumor invasion along the neural fibers, tumor necrosis, cancer emboli in the lymph gaps and vessels, vascular tumor invasion.

  19. Discordant results obtained with Francisella tularensis during in vitro and in vivo immunological studies are attributable to compromised bacterial structural integrity.

    Directory of Open Access Journals (Sweden)

    Anju Singh

    Full Text Available Francisella tularensis (Ft is a highly infectious intracellular pathogen and the causative agent of tularemia. Because Ft can be dispersed via small droplet-aerosols and has a very low infectious dose it is characterized as a category A Select Agent of biological warfare. Respiratory infection with the attenuated Live Vaccine Strain (LVS and the highly virulent SchuS4 strain of Ft engenders intense peribronchiolar and perivascular inflammation, but fails to elicit select pro-inflammatory mediators (e.g., TNF, IL-1β, IL-6, IL-12, and IFN-γ within the first ~72 h. This in vivo finding is discordant with the principally TH1-oriented response to Ft frequently observed in cell-based studies wherein the aforementioned cytokines are produced. An often overlooked confounding factor in the interpretation of experimental results is the influence of environmental cues on the bacterium's capacity to elicit certain host responses. Herein, we reveal that adaptation of Ft to its mammalian host imparts an inability to elicit select pro-inflammatory mediators throughout the course of infection. Furthermore, in vitro findings that non-host adapted Ft elicits such a response from host cells reflect aberrant recognition of the DNA of structurally-compromised bacteria by AIM2-dependent and -independent host cell cytosolic DNA sensors. Growth of Ft in Muller-Hinton Broth or on Muller-Hinton-based chocolate agar plates or genetic mutation of Ft was found to compromise the structural integrity of the bacterium thus rendering it capable of aberrantly eliciting pro-inflammatory mediators (e.g., TNF, IL-1β, IL-6, IL-12, and IFN-γ. Our studies highlight the profound impact of different growth conditions on host cell response to infection and demonstrate that not all in vitro-derived findings may be relevant to tularemia pathogenesis in the mammalian host. Rational development of a vaccine and immunotherapeutics can only proceed from a foundation of knowledge based upon

  20. Results from Mobile Lab Measurements Obtained in the Barnett Shale with Emphasis on Methane and Gaseous Mercury Emissions (Fort Worth, TX)

    Science.gov (United States)

    Laine, P. L.; Lan, X.; Anderson, D.; Talbot, R. W.

    2013-12-01

    Our work is part of a comprehensive analysis conducted through a collaboration of ground based measurements and airborne measurements with several research groups in order to gain a better understanding of methane and mercury emissions in the Barnett Shale. It's a vast rock formation that sits in the 5,000 square miles surrounding the Fort Worth area. To get the gas to market requires an underground highway of pipelines and compression stations. Texas state records show that since 2000 the number of gas compressors in the Barnett Shale has tripled (from a few hundred to 1,300), and they're ever infringing on populated areas. Recent preliminary data reported by Pétron et al. and Tollefson et al. (from the natural-gas operations in Denver-Julesburg Basin) point to CH4 loss from the process of 4-8%, not including additional losses in the pipeline and distribution system. Additionally, Howarth et al. have conducted a comprehensive analysis of greenhouse gases (methane, in particular) emitted from shale gas as a result of hydraulic fracturing and they estimate up to 8% of all natural gas mined from shale formations leaks to the atmosphere. Not only is this cause for alarm due to the global warming potential of methane, but we would expect similar losses of additional (potentially harmful) gases, i.e., atmospheric Hg, from the extraction systems. These preliminary findings are higher than the current U.S. Environment Protection Agency (EPA) leakage estimate of 2.3 percent. Our strategy employs the use of our mobile laboratory, a four door Chevrolet Silverado pickup truck with a camper shell, outfitted with trace gas instrumentation including a Picarro G2132i and a Tekran 2537 mercury analyzer. The Picarro cavity ring down instrument has high precision and accuracy H2O, CO2, CH4, and 13δC in CH4 and CO2 with very little drift due to precise temperature and pressure controls. The Tekran mercury analyzer allows for accurate total gaseous mercury measurements via

  1. Improving Prevention, Early Recognition and Management of Acute Kidney Injury after Major Surgery: Results of a Planning Meeting with Multidisciplinary Stakeholders

    Directory of Open Access Journals (Sweden)

    Matthew T James

    2014-08-01

    Full Text Available Purpose of review: Acute kidney injury (AKI is common after major surgery, and is associated with morbidity, mortality, increased length of hospital stay, and high health care costs. Although recent guidelines for AKI provide recommendations for identification of patients at risk, monitoring, diagnosis, and management of AKI, there is lack of understanding to guide successful implementation of these recommendations into clinical practice. Sources of information: We held a planning meeting with multidisciplinary stakeholders to identify barriers, facilitators, and strategies to implement recommendations for prevention, early identification, and management of AKI after major surgery. Barriers and facilitators to knowledge use for peri-operative AKI prevention and care were discussed. Findings: Stakeholders identified barriers in knowledge (how to identify high-risk patients, what criteria to use for diagnosis of AKI, attitudes (self-efficacy in preventive care and management of AKI, and behaviors (common use of diuretics, non-steroidal anti-inflammatory drugs, withholding of intravenous fluids, and competing time demands in peri-operative care. Educational, informatics, and organizational interventions were identified by stakeholders as potentially useful elements for future interventions for peri-operative AKI. Limitation: Meeting participants were from a single centre. Implications: The information and recommendations obtained from this stakeholder's meeting will be useful to design interventions to improve prevention and early care for AKI after major surgery.

  2. Results obtained during wall breaching research

    CSIR Research Space (South Africa)

    Hattingh, S

    2008-11-01

    Full Text Available To understand the physics of what is happening inside the wall directly after the detonation and the application of this knowledge in the improvement of the charge Measure the shock/stress waves in the masonry material and then in the wall as a whole... to maximise the effect of the charges on the walls and to broaden the knowledge of the physics of shock and stress waves. The thickness and characteristics of walls are not usually known in an operation. The effect of the charges on real buildings is still...

  3. Evaluation and modelling of the size fractionated aerosol particle number concentration measurements nearby a major road in Helsinki - Part I: Modelling results within the LIPIKA project

    Science.gov (United States)

    Pohjola, M. A.; Pirjola, L.; Karppinen, A.; Härkönen, J.; Korhonen, H.; Hussein, T.; Ketzel, M.; Kukkonen, J.

    2007-08-01

    A field measurement campaign was conducted near a major road "Itäväylä" in an urban area in Helsinki in 17-20 February 2003. Aerosol measurements were conducted using a mobile laboratory "Sniffer" at various distances from the road, and at an urban background location. Measurements included particle size distribution in the size range of 7 nm-10 μm (aerodynamic diameter) by the Electrical Low Pressure Impactor (ELPI) and in the size range of 3-50 nm (mobility diameter) by Scanning Mobility Particle Sizer (SMPS), total number concentration of particles larger than 3 nm detected by an ultrafine condensation particle counter (UCPC), temperature, relative humidity, wind speed and direction, driving route of the mobile laboratory, and traffic density on the studied road. In this study, we have compared measured concentration data with the predictions of the road network dispersion model CAR-FMI used in combination with an aerosol process model MONO32. For model comparison purposes, one of the cases was additionally computed using the aerosol process model UHMA, combined with the CAR-FMI model. The vehicular exhaust emissions, and atmospheric dispersion and transformation of fine and ultrafine particles was evaluated within the distance scale of 200 m (corresponding to a time scale of a couple of minutes). We computed the temporal evolution of the number concentrations, size distributions and chemical compositions of various particle size classes. The atmospheric dilution rate of particles is obtained from the roadside dispersion model CAR-FMI. Considering the evolution of total number concentration, dilution was shown to be the most important process. The influence of coagulation and condensation on the number concentrations of particle size modes was found to be negligible on this distance scale. Condensation was found to affect the evolution of particle diameter in the two smallest particle modes. The assumed value of the concentration of condensable organic

  4. Evaluation and modelling of the size fractionated aerosol particle number concentration measurements nearby a major road in Helsinki ─ Part I: Modelling results within the LIPIKA project

    Directory of Open Access Journals (Sweden)

    M. Ketzel

    2007-08-01

    Full Text Available A field measurement campaign was conducted near a major road "Itäväylä" in an urban area in Helsinki in 17–20 February 2003. Aerosol measurements were conducted using a mobile laboratory "Sniffer" at various distances from the road, and at an urban background location. Measurements included particle size distribution in the size range of 7 nm–10 μm (aerodynamic diameter by the Electrical Low Pressure Impactor (ELPI and in the size range of 3–50 nm (mobility diameter by Scanning Mobility Particle Sizer (SMPS, total number concentration of particles larger than 3 nm detected by an ultrafine condensation particle counter (UCPC, temperature, relative humidity, wind speed and direction, driving route of the mobile laboratory, and traffic density on the studied road. In this study, we have compared measured concentration data with the predictions of the road network dispersion model CAR-FMI used in combination with an aerosol process model MONO32. For model comparison purposes, one of the cases was additionally computed using the aerosol process model UHMA, combined with the CAR-FMI model. The vehicular exhaust emissions, and atmospheric dispersion and transformation of fine and ultrafine particles was evaluated within the distance scale of 200 m (corresponding to a time scale of a couple of minutes. We computed the temporal evolution of the number concentrations, size distributions and chemical compositions of various particle size classes. The atmospheric dilution rate of particles is obtained from the roadside dispersion model CAR-FMI. Considering the evolution of total number concentration, dilution was shown to be the most important process. The influence of coagulation and condensation on the number concentrations of particle size modes was found to be negligible on this distance scale. Condensation was found to affect the evolution of particle diameter in the two smallest particle modes. The assumed value of the concentration of

  5. Result

    African Journals Online (AJOL)

    Tsinuel

    BACKGROUND: Neonatal deaths in general, early neonatal deaths in particular now represent two- third of infant deaths and one-third of under-five deaths worldwide. Therefore, improving newborn survival is a major priority in child health today. Negotiation of improved neonatal health care practice into the community ...

  6. CIEMAT Interlaboratories Comparison of the Results obtained in the Proficiency Test Run by IAEA; Comparacion Interlaboratorios del CIEMAT de los Resultados Obtenidos en la Prueba de Capacitacion de Analisis de Transuranicos en Cenizas propocionadas por el OIEA

    Energy Technology Data Exchange (ETDEWEB)

    Gasco, C.; Anton, M. P.; Alvarez, A.; Navarro, N.; Meral, J.; Gonzalez, A.; Higueras Lafaja, E. [Ciemat. Madrid (Spain)

    2000-07-01

    This report contains the results obtained by two different laboratories from CIEMAT after participating in the Proficiency Test organised by IAEA (International Atomic Energy Agency) in 1999. This test involves the analysis of fly ashes containing natural radionuclides and different amounts of added transuranics. The extraction techniques, counting methods and results obtained are detailed. This type of test are used for the labs to achieve their accreditation and check the reliability of the procedures routinely employed. (Author) 4 refs.

  7. Short- and long-term effects of major organisational change on minor psychiatric disorder and self-rated health: results from the Whitehall II study.

    Science.gov (United States)

    Falkenberg, Helena; Fransson, Eleonor I; Westerlund, Hugo; Head, Jenny A

    2013-10-01

    To investigate short- and long-term effects of major organisational change on minor psychiatric disorder and self-rated health for women and men in different employment grades. Minor psychiatric disorder and self-rated health among 6710 British civil servants (1993 women and 4717 men) in three employment grades from the Whitehall II study were examined from 1985 to 1988 under stable employment conditions. The short-term effects of organisational change were investigated in 1991-1993 after a time of major restructuring aiming at increasing the influence of market forces in the civil service and the long-term effects were investigated in 1997-1999. Those who had experienced organisational change and those who anticipated organisational change reported more negative short-term health effects (minor psychiatric disorder and poor self-rated health) compared with those who reported no change. No major differences were found depending on employment grade or gender. The negative health effects had diminished during 1997-1999 for those who reported that a major change had happened before 1991-1993. Those who anticipated an organisational change in 1991-1993 still reported more ill-health in 1997-1999 (both minor psychiatric disorder and self-reported health) than those in the comparison group. The results indicate that organisational change affects employees' health negatively in the short term but also that it is possible to recover from such negative effects. As it was not possible to discern any definite difference between the gender and grades, the results point at the importance of working proactively to implement organisational change for women and men at all levels.

  8. Major depression

    Science.gov (United States)

    Depression - major; Depression - clinical; Clinical depression; Unipolar depression; Major depressive disorder ... providers do not know the exact causes of depression. It is believed that chemical changes in the ...

  9. results

    Directory of Open Access Journals (Sweden)

    Salabura Piotr

    2017-01-01

    Full Text Available HADES experiment at GSI is the only high precision experiment probing nuclear matter in the beam energy range of a few AGeV. Pion, proton and ion beams are used to study rare dielectron and strangeness probes to diagnose properties of strongly interacting matter in this energy regime. Selected results from p + A and A + A collisions are presented and discussed.

  10. Statistical data and results obtained on irradiated transistors 2N.2221 Sesco and 2N.2907 SGS; Donnees de fiabilite et resultats statistiques obtenus sur des transistors 2n.2221 Sesco et 2n.2907 SGS irradies

    Energy Technology Data Exchange (ETDEWEB)

    Blin, A; Le Ber, J

    1966-07-01

    This document provides results obtained on many samples of transistors irradiated in the laboratories of the Institut of Nuclear Physic of Lyon. The physical aspects of the irradiation,the statistical aspects of the study and the reliability under irradiation have been studied, but the accent is done on the statistical analysis. (A.L.B.)

  11. To report the obtained results in the operation multicycle study of the L V U-1 using design data with the FCSII (1D) and PRESTO (3D) codes of the FMS system

    International Nuclear Information System (INIS)

    Montes T, J.L.; Cortes C, C.C.

    1991-07-01

    This work is to carry out a multicycle study for the Laguna Verde U-1 reactor with the FCS-II (1 - 20 cycles) and PRESTO (1 - 6 cycles) codes and to compare the obtained results against those reported by General Electric. (Author)

  12. Do the results of respirable dust samples obtained from direct-on-filter X-ray diffraction, direct-on-filter infrared and indirect infrared (KBr pellet) methods correlate?

    CSIR Research Space (South Africa)

    Pretorius, C

    2010-11-01

    Full Text Available The objective of this study was to determine whether a correlation exists between the quartz results obtained from direct-on-filter X-ray Diffraction analysis, direct-on-filter Fourier-Transform Infrared analysis and indirect analysis (Potassium...

  13. Quantitative scintiscanning in the follow-up observation of carcinomas of the breast. A correlation of results thus obtained with X-ray and laboratory findings to evaluate the effects of local irradiation or cytostatics

    International Nuclear Information System (INIS)

    Bauer, U.

    1985-01-01

    Scintiscan studies using 99m-Tc methylene diphosphonate and the region-of-interest technique were carried out in order to obtain additional quantitative data on bone metastases that had already been confirmed by X-rays. Different degrees of density allowed to calculate the quotient of the ratio between bones and soft tissues. Changes in the behaviour of this quotient were found to provide information relevant to the value of chemotherapy or irradiation. Reduced quotients were interpreted as being a sign of a favourable response to treatment. One major drawback of this quotient is that it cannot be used without restriction for all kinds of therapy of laboratory examinations to assess the progress or remission of bone metastases. Nevertheless, it seems a meaningful parameter in the surveillance of patients receiving cytostatics or radiotherapy. (TRV) [de

  14. Report on the finally obtained results of the study of the basement technology for environmentally friendly type metal base material regenerative utilization; Kankyo chowagata kinzokukei sozai kaisei riyo kiban gijutsu no kenkyu saishu seika hokokusho

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2000-07-01

    For the purpose of contributing to the resource recycling and global environmental preservation, the R and D of metal base scrap regenerative utilization technology were conducted, and the report on the finally obtained results was summed up. As to the technology to remove impurities by the solid phase treatment, the Cu removal rate of more than 96% was made possible by the low temperature fracturing technology, and that of more than 90% by the hue difference discrimination separation system technology. From the results of the FS on the low temperature fracturing technology applied to car scraps, it was found out that the present price condition is not economically efficient in the present price condition, but a possibility of achieving the removal rate of 54% in the initial plan was obtained if applying the hue difference discrimination separation system to the pretreatment. Concerning the Sn removal, the Sn removal rate of more than 70% was obtained by the gaseous phase sulfuration method, and that of more than 50% was obtained in Sn removal/Cu removal/Zn removal by the oxidation reaction method. The targets were achieved. Relating to the treatment of impurities by melting (liquid phase), the Cu removal/Sn removal technology under reduced pressure was effective in vacuum melting furnace of 2-ton scale, but the needs for the development of large capacity plasma torch were recognized in that of 40-ton scale for practical use. (NEDO)

  15. Evaluation of two transport aircraft and several ground test vehicle friction measurements obtained for various runway surface types and conditions. A summary of test results from joint FAA/NASA Runway Friction Program

    Science.gov (United States)

    Yager, Thomas J.; Vogler, William A.; Baldasare, Paul

    1990-01-01

    Tests with specially instrumented NASA Boeing 737 and 727 aircraft together with several different ground friction measuring devices were conducted for a variety of runway surface types and conditions. These tests are part of joint FAA/NASA Aircraft/Ground Vehicle Runway Friction Program aimed at obtaining a better understanding of aircraft ground handling performance under adverse weather conditions and defining relationships between aircraft and ground vehicle tire friction measurements. Aircraft braking performance on dry, wet, snow and ice-covered runway conditions is discussed as well as ground vehicle friction data obtained under similar runway conditions. For a given contaminated runway surface condition, the correlation between ground vehicles and aircraft friction data is identified. The influence of major test parameters on friction measurements such as speed, test tire characteristics, type and amount of surface contaminant, and ambient temperature are discussed. The effect of surface type on wet friction levels is also evaluated from comparative data collected on grooved and ungrooved concrete and asphalt surfaces.

  16. The Ursa Major supercluster

    International Nuclear Information System (INIS)

    Schuch, N.J.

    1983-01-01

    An optical and a radio survey have been carried out. The optical observations consist of a spectroscopic survey in which redshift data for cluster galaxies and optical identifications of radio sources were obtained with the 98-inch Isaac Newton telescope at the Royal Greenwich Observatory, and the 200-inch Hale telescope; the photographic survey in B, V and R colors was made with the 48-inch Schmidt telescope at Palomar. Some results on the galaxy distribution in the Ursa Major supercluster are briefly discussed. (Auth.)

  17. Obtaining of inulin acetate

    OpenAIRE

    Khusenov, Arslonnazar; Rakhmanberdiev, Gappar; Rakhimov, Dilshod; Khalikov, Muzaffar

    2014-01-01

    In the article first obtained inulin ester inulin acetate, by etherification of inulin with acetic anhydride has been exposed. Obtained product has been studied using elementary analysis and IR spectroscopy.

  18. Lack of knowledge of HIV status a major barrier to HIV prevention, care and treatment efforts in Kenya: results from a nationally representative study.

    Directory of Open Access Journals (Sweden)

    Peter Cherutich

    Full Text Available BACKGROUND: We analyzed HIV testing rates, prevalence of undiagnosed HIV, and predictors of testing in the Kenya AIDS Indicator Survey (KAIS 2007. METHODS: KAIS was a nationally representative sero-survey that included demographic and behavioral indicators and testing for HIV, HSV-2, syphilis, and CD4 cell counts in the population aged 15-64 years. We used gender-specific multivariable regression models to identify factors independently associated with HIV testing in sexually active persons. RESULTS: Of 19,840 eligible persons, 80% consented to interviews and blood specimen collection. National HIV prevalence was 7.1% (95% CI 6.5-7.7. Among ever sexually active persons, 27.4% (95% CI 25.6-29.2 of men and 44.2% (95% CI 42.5-46.0 of women reported previous HIV testing. Among HIV-infected persons, 83.6% (95% CI 76.2-91.0 were unaware of their HIV infection. Among sexually active women aged 15-49 years, 48.7% (95% CI 46.8-50.6 had their last HIV test during antenatal care (ANC. In multivariable analyses, the adjusted odds ratio (AOR for ever HIV testing in women ≥35 versus 15-19 years was 0.2 (95% CI: 0.1-0.3; p<0.0001. Other independent associations with ever HIV testing included urban residence (AOR 1.6, 95% CI: 1.2-2.0; p = 0.0005, women only, highest wealth index versus the four lower quintiles combined (AOR 1.8, 95% CI: 1.3-2.5; p = 0.0006, men only, and an increasing testing trend with higher levels of education. Missed opportunities for testing were identified during general or pregnancy-specific contacts with health facilities; 89% of adults said they would participate in home-based HIV testing. CONCLUSIONS: The vast majority of HIV-infected persons in Kenya are unaware of their HIV status, posing a major barrier to HIV prevention, care and treatment efforts. New approaches to HIV testing provision and education, including home-based testing, may increase coverage. Targeted interventions should involve sexually active men, sexually

  19. An open pilot study of zonisamide augmentation in major depressive patients not responding to a low dose trial with duloxetine: preliminary results on tolerability and clinical effects

    Directory of Open Access Journals (Sweden)

    Benvenuti Marzia

    2011-09-01

    Full Text Available Abstract Background Despite multiple antidepressant options, major depressive disorder (MDD still faces high non-response rates, eventually requiring anticonvulsant augmentation strategies too. The aim of this study was to explore such a potential role for zonisamide. Methods A total of 40 MDD outpatients diagnosed using the Diagnostic and Statistical Manual for Mental Disorders, fourth edition criteria entered a 24 week open trial receiving duloxetine 60 mg/day for the first 12 weeks and subsequently (weeks 12 to 24 augmentation with zonisamide 75 mg/day if they did not respond to the initial monotherapy. Efficacy and tolerability were assessed using the Hamilton Scales for Anxiety and Depression (a 12 week score ≥50% vs baseline defined 'non-response', the Arizona Sexual Experience Scale, the Patient Rated Inventory of Side Effects and the Young Mania Rating Scale. Results At week 12, 15 patients out of 39 (38.5% were responders, and 1 had dropped out; remarkably, 14 patients out of 24 (58.3% had achieved response by week 24. Poor concentration and general malaise were associated with non-response both at week 12 and 24 (P = 0.001, while loss of libido and reduced energy were prominent among final timepoint non-responders. Patients receiving zonisamide also experienced weight reduction (2.09 ± 12.14 kg; P = 0.001 independently of the outcome. Conclusions Although only a preliminary study due to strong methodological limitations, and thus requiring confirmation by further controlled investigations, the current results indicate zonisamide may be a potential augmentation option for some depressed patients receiving low doses of duloxetine.

  20. Preoperative Radiotherapy and Wide Resection for Soft Tissue Sarcomas: Achieving a Low Rate of Major Wound Complications with the Use of Flaps. Results of a Single Surgical Team

    Directory of Open Access Journals (Sweden)

    Lester Wai Mon Chan

    2018-01-01

    Full Text Available BackgroundSurgery in combination with radiotherapy (RT has become the standard of care for most soft tissue sarcomas. The choice between pre- and postoperative RT is controversial. Preoperative RT is associated with a 32–35% rate of major wound complications (MWC and 16–25% rate of reoperation. The role of vascularized soft tissue “flaps” in reducing complications is unclear. We report the outcomes of patients treated with preoperative RT, resection, and flap reconstruction.Patients and methods122 treatment episodes involving 117 patients were retrospectively reviewed. All patients were treated with 50.4 Gy of external beam radiation. Surgery was performed at 4–8 weeks after completion of RT by the same combination of orthopedic oncology and plastic reconstructive surgeon. Defects were reconstructed with 64 free and 59 pedicled/local flaps.Results30 (25% patients experienced a MWC and 17 (14% required further surgery. 20% of complications were exclusively related to the donor site. There was complete or partial loss of three flaps. There was no difference in the rate of MWC or reoperation for complications with respect to age, sex, tumor site, previous unplanned excision, tumor grade, depth, and type of flap. Tumor size ≥8 cm was associated with a higher rate of reoperation (11/44 vs 6/78; P = 0.008 but the rate of MWC was not significant (16/44 vs 14/78; P = 0.066.ConclusionThe use of soft tissue flaps is associated with a low rate of MWC and reoperation. Our results suggest that a high rate of flap usage may be required to observe a reduction in complication rates.

  1. Evidence of a major locus for lipoprotein lipase (LPL) activity in addition to a pleiotropic locus for both LPL and fasting insulin: results from the HERITAGE Family Study.

    Science.gov (United States)

    Hong, Y; Rice, T; Després, J P; Gagnon, J; Nadeau, A; Bergeron, J; Pérusse, L; Bouchard, C; Leon, A S; Skinner, J S; Wilmore, J H; Rao, D C

    1999-06-01

    A major gene hypothesis for heparin releasable plasma lipoprotein lipase (PH-LPL) activity was assessed using segregation analyses of data on 495 members in 98 normolipidemic sedentary families of Caucasian descent who participated in the HERITAGE Family Study. Segregation analyses were performed on PH-LPL adjusted for age, and on PH-LPL activity adjusted for age and fasting insulin. Prior to adjustment for insulin, neither a major gene effect nor a multifactorial component could be rejected, and support for a major gene was equivocal i.e. neither the Mendelian transmission nor the no transmission (equal tau s) models were rejected. However, after adjusting for the effects of insulin, a major gene effect on PH-LPL activity was unambiguous. The putative locus accounted for 60% of the total phenotypic variance, and the homozygous recessive form affected 10% (q2) of the sample (i.e. gene frequency (q) = 0.31), and led to a low PH-LPL value. The lack of a significant multifactorial effect suggested that the familial etiology of PH-LPL activity adjusted for insulin was likely to be primarily a function of the major locus. In conclusion, the present study is the first to report segregation analyses on PH-LPL activity prior to and after adjusting for insulin, and suggests that there is an indication of a pleiotropic genetic effect on PH-LPL activity and insulin, in addition to a major gene effect on PH-LPL activity alone.

  2. Preoperative Radiotherapy and Wide Resection for Soft Tissue Sarcomas: Achieving a Low Rate of Major Wound Complications with the Use of Flaps. Results of a Single Surgical Team.

    Science.gov (United States)

    Chan, Lester Wai Mon; Imanishi, Jungo; Grinsell, Damien Glen; Choong, Peter

    2017-01-01

    Surgery in combination with radiotherapy (RT) has become the standard of care for most soft tissue sarcomas. The choice between pre- and postoperative RT is controversial. Preoperative RT is associated with a 32-35% rate of major wound complications (MWC) and 16-25% rate of reoperation. The role of vascularized soft tissue "flaps" in reducing complications is unclear. We report the outcomes of patients treated with preoperative RT, resection, and flap reconstruction. 122 treatment episodes involving 117 patients were retrospectively reviewed. All patients were treated with 50.4 Gy of external beam radiation. Surgery was performed at 4-8 weeks after completion of RT by the same combination of orthopedic oncology and plastic reconstructive surgeon. Defects were reconstructed with 64 free and 59 pedicled/local flaps. 30 (25%) patients experienced a MWC and 17 (14%) required further surgery. 20% of complications were exclusively related to the donor site. There was complete or partial loss of three flaps. There was no difference in the rate of MWC or reoperation for complications with respect to age, sex, tumor site, previous unplanned excision, tumor grade, depth, and type of flap. Tumor size ≥8 cm was associated with a higher rate of reoperation (11/44 vs 6/78; P  = 0.008) but the rate of MWC was not significant (16/44 vs 14/78; P  = 0.066). The use of soft tissue flaps is associated with a low rate of MWC and reoperation. Our results suggest that a high rate of flap usage may be required to observe a reduction in complication rates.

  3. The effect of major adverse renal cardiovascular event (MARCE) incidence, procedure volume, and unit cost on the hospital savings resulting from contrast media use in inpatient angioplasty.

    Science.gov (United States)

    Keuffel, Eric; McCullough, Peter A; Todoran, Thomas M; Brilakis, Emmanouil S; Palli, Swetha R; Ryan, Michael P; Gunnarsson, Candace

    2018-04-01

    To determine the net economic impact of switching from low-osmolar contrast media (LOCM) to iso-osmolar contrast media (IOCM; iodixanol) in patients undergoing inpatient coronary or peripheral angioplasty in the United States (US). A budget impact model (BIM) was developed from a hospital perspective. Nationally representative procedural and contrast media prevalence rates, along with MARCE (major adverse renal cardiovascular event) incidence and episode-related cost data were derived from Premier Hospital Data (October 2014 to September 2015). A previously estimated relative risk reduction in MARCE associated with IOCM usage (9.3%) was applied. The higher cost of IOCM was included when calculating the net impact estimates at the aggregate, hospital type, and per hospital levels. One-way (±25%) and probabilistic sensitivity analyses identified the model's most important inputs. Based on weighted analysis, 513,882 US inpatient angioplasties and 35,610 MARCE cases were estimated annually. Switching to an "IOCM only" strategy from a "LOCM only" strategy increases contrast media cost, but prevents 2,900 MARCE events. The annual budget impact was an estimated saving of $30.71 million, aggregated across all US hospitals, $6,316 per hospital, or $60 per procedure. Net savings were maintained across all univariate sensitivity analyses. While MARCE/event-free cost differential was the most important factor driving total net savings for hospitals in the Northeast and West, procedural volume was important in the Midwest and rural locations. Switching to an "IOCM only" strategy from a "LOCM only" approach yields substantial net global savings to hospitals, both at the national level and within hospital sub-groups. Hospital administrators should maintain awareness of the factors that are likely to be more influential for their hospital and recognize that purchasing on the basis of lower contrast media cost may result in higher overall costs for patients undergoing inpatient

  4. Clinical characteristics and treatment outcomes of patients with major depressive disorder and comorbid anxiety disorders - results from a European multicenter study.

    Science.gov (United States)

    Dold, Markus; Bartova, Lucie; Souery, Daniel; Mendlewicz, Julien; Serretti, Alessandro; Porcelli, Stefano; Zohar, Joseph; Montgomery, Stuart; Kasper, Siegfried

    2017-08-01

    This naturalistic European multicenter study aimed to elucidate the association between major depressive disorder (MDD) and comorbid anxiety disorders. Demographic and clinical information of 1346 MDD patients were compared between those with and without concurrent anxiety disorders. The association between explanatory variables and the presence of comorbid anxiety disorders was examined using binary logistic regression analyses. 286 (21.2%) of the participants exhibited comorbid anxiety disorders, 10.8% generalized anxiety disorder (GAD), 8.3% panic disorder, 8.1% agoraphobia, and 3.3% social phobia. MDD patients with comorbid anxiety disorders were characterized by younger age (social phobia), outpatient status (agoraphobia), suicide risk (any anxiety disorder, panic disorder, agoraphobia, social phobia), higher depressive symptom severity (GAD), polypsychopharmacy (panic disorder, agoraphobia), and a higher proportion receiving augmentation treatment with benzodiazepines (any anxiety disorder, GAD, panic disorder, agoraphobia, social phobia) and pregabalin (any anxiety disorder, GAD, panic disorder). The results in terms of treatment response were conflicting (better response for panic disorder and poorer for GAD). The logistic regression analyses revealed younger age (any anxiety disorder, social phobia), outpatient status (agoraphobia), suicide risk (agoraphobia), severe depressive symptoms (any anxiety disorder, GAD, social phobia), poorer treatment response (GAD), and increased administration of benzodiazepines (any anxiety disorder, agoraphobia, social phobia) and pregabalin (any anxiety disorder, GAD, panic disorder) to be associated with comorbid anxiety disorders. Our findings suggest that the various anxiety disorders subtypes display divergent clinical characteristics and are associated with different variables. Especially comorbid GAD appears to be characterized by high symptom severity and poor treatment response. Copyright © 2017 Elsevier Ltd. All

  5. Annual report on major results and progress of Fusion Research and Development Directorate of JAEA from April 1, 2006 to March 31, 2007

    International Nuclear Information System (INIS)

    Suzuki, Satoshi; Ishii, Yasutomo; Sukegawa, Atsuhiko; Iwai, Yasunori; Nakamura, Hiroo; Sugie, Tatsuo

    2008-08-01

    This annual report provides an overview of major results and progress on research and development (R and D) activities at Fusion Research and Development Directorate of Japan Atomic Energy Agency (JAEA) from April 1, 2006 to March 31, 2007, including those performed in collaboration with other research establishments of JAEA, research institutes, and universities. In JT-60, as a result of ferritic steel tiles (FSTs) installation to reduce the toroidal field ripple and the application of the real time current profile control, high boot strap current fraction (∼0.7) has successfully been sustained about 8 s. In addition, the conceptual design of JT-60SA, which was placed as a combined project of JA-EU Satellite Tokamak Programme under the Broader Approach Programme and JAEA's programme for national use, was progressed. In theoretical and analytical researches, studies on ITB events and their triggers, plasma shape effect on edge stability and driven magnetic island evolution in rotating plasmas were progressed. In the NEXT project, computer simulations of the plasma turbulence were progressed. In fusion reactor technologies, R and Ds for ITER and fusion DEMO plants have been carried out. For ITER, a steady state operation of the 170GHz gyrotron up to 10min with 0.82MW was demonstrated. Also current density of the neutral beam injector has been extended to 146A/m 2 at 0.84MeV. In the ITER Test Blanket Module (TBM), designs and R and Ds of Water and Helium Cooled Solid Breeder TBMs including tritium breeder/multiplier materials were progressed. Tritium processing technology for breeding blankets and neutronics integral experiments with a blanket mockup were also progressed. For ITER and DEMO blankets, studies on neutron irradiation effects and ion irradiation effects on F82H steel characteristics were continued using HFIR, TIARA and so on. In the IFMIF program, transitional activities to EVEDA were continued. In the ITER Program, under the framework of the ITER

  6. MODELS OF MAJOR ADVERSE CARDIAC EVENT RISK USING RESULTS OF EXERCISE STRESS ECHOCARDIOGRAPHY WITH NONINVASIVE CORONARY ARTERY FLOW ASSESSMENT IN PATIENTS WITH ISCHEMIC HEART DISEASE

    Directory of Open Access Journals (Sweden)

    A. V. Zagatina

    2017-01-01

    Full Text Available Ultrasound non-invasive coronary artery imaging contributes to the diagnosis of ischemic heart disease (IHD in clinical practice. However, data of the prognostic value obtained from a complex analysis of contractility disorders and coronary blood flow parameters during exercise tests in the world literature are still not available. Aim. To develop risk models for adverse outcomes in patients with probable or definite IHD based on the results of a stress test with a noninvasive coronary blood flow study. Material and methods. Medical data of 689 patients with probable or definite IHD who underwent stress echocardiography with satisfactory visualization of the anterior interventricular artery (AIVA were included in the analysis. All patients had stress echocardiography on a horizontal bicycle ergometer. Registration of coronary blood flow in the middle third of the AIVA was performed at rest and at the peak of the load with calculation of the coronary reserve value. Further patient follow-up lasted 3 years. Models of further negative outcomes were developed on the basis of the stress echocardiography results and of coronary blood flow parameters. Results. Three models that take into account the factors associated with further mortality, mortality/myocardial infarction and sum of negative outcomes were developed in the study. These models divide a cohort of patients with probable or definite IHD into groups of low, medium and very high risks. Factors associated with the risk of death include: age >56 years, load power <100 W, breach of contractility in the blood supply zone of the circumflex artery initially and during exercise, the difference in blood flow velocities in the AIVA<10 cm/s, coronary reserve of AIVA<2. The risk model of death, taking into account these factors, suggests dividing patients into low-risk group if there are ≤2 factors (mortality 0.6% for 3 years, medium risk – from 2 to 4 factors (mortality 1.8%, high risk – ≥5

  7. Major Links.

    Science.gov (United States)

    Henderson, Tona

    1995-01-01

    Provides electronic mail addresses for resources and discussion groups related to the following academic majors: art, biology, business, chemistry, computer science, economics, health sciences, history, literature, math, music, philosophy, political science, psychology, sociology, and theater. (AEF)

  8. Major Roads

    Data.gov (United States)

    Minnesota Department of Natural Resources — This data set contains roadway centerlines for major roads (interstates and trunk highways) found on the USGS 1:24,000 mapping series. These roadways are current...

  9. Ten years of sodium cooled steam generator tests on the C.G.V.S. Synthesis of the results obtained on these equipments and operation experiments of an industrial size test facility

    International Nuclear Information System (INIS)

    Fontaine, J.P.; Llory, M.; Quinet, J.L.

    1984-04-01

    From 1970 to 1980, Electricite de France carried out tests on four steam generators of the fast neutron reactor series on an industrial size testing equipment, the C.G.V.S. (large power testing Circuit for Steam Generators heated by Sodium). After a presentation of the testing installation, types of tests carried out and tested apparatus, a balance of lessons drawn from the circuit exploitation, and from the main results obtained on the tested equipments and on the means of calculation COPI and SICLE codes developed or adopted to simulate steam generator operation. 33 figs., 50 refs [fr

  10. Predictors of poor retention on antiretroviral therapy as a major HIV drug resistance early warning indicator in Cameroon: results from a nationwide systematic random sampling

    Directory of Open Access Journals (Sweden)

    Serge Clotaire Billong

    2016-11-01

    Full Text Available Abstract Background Retention on lifelong antiretroviral therapy (ART is essential in sustaining treatment success while preventing HIV drug resistance (HIVDR, especially in resource-limited settings (RLS. In an era of rising numbers of patients on ART, mastering patients in care is becoming more strategic for programmatic interventions. Due to lapses and uncertainty with the current WHO sampling approach in Cameroon, we thus aimed to ascertain the national performance of, and determinants in, retention on ART at 12 months. Methods Using a systematic random sampling, a survey was conducted in the ten regions (56 sites of Cameroon, within the “reporting period” of October 2013–November 2014, enrolling 5005 eligible adults and children. Performance in retention on ART at 12 months was interpreted following the definition of HIVDR early warning indicator: excellent (>85%, fair (85–75%, poor (<75; and factors with p-value < 0.01 were considered statistically significant. Results Majority (74.4% of patients were in urban settings, and 50.9% were managed in reference treatment centres. Nationwide, retention on ART at 12 months was 60.4% (2023/3349; only six sites and one region achieved acceptable performances. Retention performance varied in reference treatment centres (54.2% vs. management units (66.8%, p < 0.0001; male (57.1% vs. women (62.0%, p = 0.007; and with WHO clinical stage I (63.3% vs. other stages (55.6%, p = 0.007; but neither for age (adults [60.3%] vs. children [58.8%], p = 0.730 nor for immune status (CD4351–500 [65.9%] vs. other CD4-staging [59.86%], p = 0.077. Conclusions Poor retention in care, within 12 months of ART initiation, urges active search for lost-to-follow-up targeting preferentially male and symptomatic patients, especially within reference ART clinics. Such sampling strategy could be further strengthened for informed ART monitoring and HIVDR prevention perspectives.

  11. A Taxometric Investigation of "DSM-IV" Major Depression in a Large Outpatient Sample: Interpretable Structural Results Depend on the Mode of Assessment

    Science.gov (United States)

    Ruscio, John; Brown, Timothy A.; Ruscio, Ayelet Meron

    2009-01-01

    Most taxometric studies of depressive constructs have drawn indicators from self-report instruments that do not bear directly on the "Diagnostic and Statistical Manual of Mental Disorders, 4th edition (DSM-IV)" diagnostic construct of major depressive disorder (MDD). The present study examined the latent structure of MDD using indicator sets…

  12. The treatment of irradiated uranium fuel. Results obtained while operating the pilot plant at Fontenay-aux-Roses; Le traitement de l'uranium irradie. Resultats d'exploitation de l'usine-pilote de Fontenay-aux-Roses

    Energy Technology Data Exchange (ETDEWEB)

    Regnaut, P; Faugeras, P; Brut, A; Helou, R; Redon, A [Commissariat a l' Energie Atomique, Saclay (France). Centre d' Etudes Nucleaires

    1958-07-01

    In this paper the results obtained from four years operation of the pilot plant when using bars of increasing activity, are summarised and compared with the results of parallel studies carried out in the laboratory. As a conclusion to the article, the optimum conditions for the different phases of a process based on solvent extraction are given. (author)Fren. [French] Cette conference resume les resultats obtenus durant quatre annees de fonctionnement de l'Usine-Pilote, avec des barreaux d'activite croissante et les compare aux resultats d'etudes conduites parallelement en laboratoire. En conclusion sont donnees les conditions optima pour les differentes phases d'un procede base sur l'extraction par solvant. (auteur)

  13. Fundamental principles for obtaining agricultural produce of standard purity in those parts of the Russian Federation which were radioactively contaminated as a result of the Chernobyl accident, and the effectiveness of the measures being taken

    International Nuclear Information System (INIS)

    Ratnikov, A.N.; Aleksakhin, R.M.; Popova, G.I.; Zhigareva, T.L.; Vasil'ev, A.V.

    1997-01-01

    For the decrease in radionuclide content in agricultural products a complex of countermeasures in plant and animal production should be carried out. The results from the investigations performed indicate that quarantined obtaining of high quality plant products may be achieved by optimization of crop cultivation technology when qualitatively implementing all the agrotechnical operations and introducing the techniques facilitating the decrease of radionuclide transfer to plants. The use of agricultural ameliorants (vermiculite, bentonite), capable of non-exchanging radionuclide absorption in soils, reduces the 137 Cs accumulation in yield from 1,5 to 3 times. One of the most reevaluates economically inexpensive techniques on arable and forage lands under conditions of radioactive contamination is a selection of the most productive crop species and varieties showing the minimum radionuclide accumulation. Specific distinction in 137 Cs accumulation may reach from 2 to 45 times. Variety distinction are less and account for 2 to 5 times. The basis for obtaining plant products fully satisfactory for human consumption is a rational organization of feed stuffs, production, provision for animals of complete balanced diet with minimum radionuclide content, availability of high-productive animals

  14. Determination of diets for the populations of eleven regions of the European community to be used for obtaining radioactive contamination levels. First results concerning the food consumption of individuals classified in nine age-groups

    International Nuclear Information System (INIS)

    Ledermann, S.; Lacourly, G.; Garnier, A.; Cresta, M.; Lombardo, E.

    1968-01-01

    The present document continues the report CEA-R--2979 - EUR--2768-f. The processing of the data given by the family food enquiry carried out in eleven regions of the European Community, has permitted to determine the food consumption of individuals classified in nine age-groups, in order to study the radioactive contamination levels in the food-chain. The used statistical method is described, and the obtained results are presented in form of double-entry tables giving for each region and for each age-group the mean weekly food-consumption and the contribution of each diet in nutrition principles, in minerals, vitamins, trace elements and calories. (authors) [fr

  15. Beneficial Effects of Early Enteral Nutrition After Major Rectal Surgery: A Possible Role for Conditionally Essential Amino Acids? Results of a Randomized Clinical Trial.

    Science.gov (United States)

    van Barneveld, Kevin W Y; Smeets, Boudewijn J J; Heesakkers, Fanny F B M; Bosmans, Joanna W A M; Luyer, Misha D; Wasowicz, Dareczka; Bakker, Jaap A; Roos, Arnout N; Rutten, Harm J T; Bouvy, Nicole D; Boelens, Petra G

    2016-06-01

    To investigate direct postoperative outcome and plasma amino acid concentrations in a study comparing early enteral nutrition versus early parenteral nutrition after major rectal surgery. Previously, it was shown that a low plasma glutamine concentration represents poor prognosis in ICU patients. A preplanned substudy of a previous prospective, randomized, open-label, single-centre study, comparing early enteral nutrition versus early parenteral nutrition in patients at high risk of postoperative ileus after surgery for locally advanced or locally recurrent rectal cancer. Early enteral nutrition reduced postoperative ileus, anastomotic leakage, and hospital stay. Tertiary referral centre for locally advanced and recurrent rectal cancer. A total of 123 patients with locally advanced or recurrent rectal carcinoma requiring major rectal surgery. Patients were randomized (ALEA web-based external randomization) preoperatively into two groups: early enteral nutrition (early enteral nutrition, intervention) by nasojejunal tube (n = 61) or early parenteral nutrition (early parenteral nutrition, control) by jugular vein catheter (n = 62). Eight hours after the surgical procedure artificial nutrition was started in hemodynamically stable patients, stimulating oral intake in both groups. Blood samples were collected to measure plasma glutamine, citrulline, and arginine concentrations using a validated ultra performance liquid chromatography-tandem mass spectrometric method. Baseline concentrations were comparable for both groups. Directly after rectal surgery, a decrease in plasma amino acids was observed. Plasma glutamine concentrations were higher in the parenteral group than in the enteral group on postoperative day 1 (p = 0.027) and day 5 (p = 0.008). Arginine concentrations were also significantly increased in the parenteral group at day 1 (p < 0.001) and day 5 (p = 0.001). Lower plasma glutamine and arginine concentrations were measured in the enteral group, whereas a

  16. Sex Differences in the Effect of Type 2 Diabetes on Major Cardiovascular Diseases: Results from a Population-Based Study in Italy

    Directory of Open Access Journals (Sweden)

    Paola Ballotari

    2017-01-01

    Full Text Available The aim of the study is to assess sex difference in association between type 2 diabetes and incidence of major cardiovascular events, that is, myocardial infarction, stroke, and heart failure, using information retrieved by diabetes register. The inhabitants of Reggio Emilia (Italy aged 30–84 were followed during 2012–2014. Incidence rate ratios and 95% confidence intervals were calculated using multivariate Poisson model. The age- and sex-specific event rates were graphed. Subjects with type 2 diabetes had an excess risk compared to their counterparts without diabetes for all the three major cardiovascular events. The excess risk is similar in women and men for stroke (1.8 times and heart failure (2.7 times, while for myocardial infarction, the excess risk in women is greater than the one observed in men (IRR 2.58, 95% CI 2.22–3.00 and IRR 1.78, 95% CI 1.60–2.00, resp.; P of interaction <0.0001. Women had always a lesser risk than men, but in case of myocardial infarction, the women with type 2 diabetes lost part of advantage gained by women free of diabetes (IRR 0.61, 95% CI 0.53–0.72 and IRR 0.36, 95% CI 0.33–0.39, resp.. In women with type 2 diabetes, the risk of major cardiovascular events is anticipated by 20–30 years, while in men it is by 15–20.

  17. Sex Differences in the Effect of Type 2 Diabetes on Major Cardiovascular Diseases: Results from a Population-Based Study in Italy

    Science.gov (United States)

    Greci, Marina; Manicardi, Valeria

    2017-01-01

    The aim of the study is to assess sex difference in association between type 2 diabetes and incidence of major cardiovascular events, that is, myocardial infarction, stroke, and heart failure, using information retrieved by diabetes register. The inhabitants of Reggio Emilia (Italy) aged 30–84 were followed during 2012–2014. Incidence rate ratios and 95% confidence intervals were calculated using multivariate Poisson model. The age- and sex-specific event rates were graphed. Subjects with type 2 diabetes had an excess risk compared to their counterparts without diabetes for all the three major cardiovascular events. The excess risk is similar in women and men for stroke (1.8 times) and heart failure (2.7 times), while for myocardial infarction, the excess risk in women is greater than the one observed in men (IRR 2.58, 95% CI 2.22–3.00 and IRR 1.78, 95% CI 1.60–2.00, resp.; P of interaction < 0.0001). Women had always a lesser risk than men, but in case of myocardial infarction, the women with type 2 diabetes lost part of advantage gained by women free of diabetes (IRR 0.61, 95% CI 0.53–0.72 and IRR 0.36, 95% CI 0.33–0.39, resp.). In women with type 2 diabetes, the risk of major cardiovascular events is anticipated by 20–30 years, while in men it is by 15–20. PMID:28316624

  18. Rates and factors associated with major modifications to first-line combination antiretroviral therapy: results from the Asia-Pacific region.

    Directory of Open Access Journals (Sweden)

    Stephen Wright

    Full Text Available In the Asia-Pacific region many countries have adopted the WHO's public health approach to HIV care and treatment. We performed exploratory analyses of the factors associated with first major modification to first-line combination antiretroviral therapy (ART in resource-rich and resource-limited countries in the region.We selected treatment naive HIV-positive adults from the Australian HIV Observational Database (AHOD and the TREAT Asia HIV Observational Database (TAHOD. We dichotomised each country's per capita income into high/upper-middle (T-H and lower-middle/low (T-L. Survival methods stratified by income were used to explore time to first major modification of first-line ART and associated factors. We defined a treatment modification as either initiation of a new class of antiretroviral (ARV or a substitution of two or more ARV agents from within the same ARV class.A total of 4250 patients had 961 major modifications to first-line ART in the first five years of therapy. The cumulative incidence (95% CI of treatment modification was 0.48 (0.44-0.52, 0.33 (0.30-0.36 and 0.21 (0.18-0.23 for AHOD, T-H and T-L respectively. We found no strong associations between typical patient characteristic factors and rates of treatment modification. In AHOD, relative to sites that monitor twice-yearly (both CD4 and HIV RNA-VL, quarterly monitoring corresponded with a doubling of the rate of treatment modifications. In T-H, relative to sites that monitor once-yearly (both CD4 and HIV RNA-VL, monitoring twice-yearly corresponded to a 1.8 factor increase in treatment modifications. In T-L, no sites on average monitored both CD4 & HIV RNA-VL concurrently once-yearly. We found no differences in rates of modifications for once- or twice-yearly CD4 count monitoring.Low-income countries tended to have lower rates of major modifications made to first-line ART compared to higher-income countries. In higher-income countries, an increased rate of RNA-VL monitoring was

  19. Ion exchange reactions of major inorganic cations (H+, Na+, Ca2+, Mg2+ and K+) on beidellite: Experimental results and new thermodynamic database. Toward a better prediction of contaminant mobility in natural environments

    International Nuclear Information System (INIS)

    Robin, Valentin; Tertre, Emmanuel; Beaufort, Daniel; Regnault, Olivier; Sardini, Paul; Descostes, Michael

    2015-01-01

    Highlights: • Multi-site ion exchange model for beidellite for Na + , Ca 2+ , Mg 2+ , K + and H + . • Validity over the 1–7 pH range and total normality >5 × 10 −3 mol/L. • Application to equilibrium between smectite and acidic solution from mining sites. • Impact of crystal chemistry of smectites on their sorption properties. - Abstract: To our knowledge, no thermodynamic database is available in the literature concerning ion-exchange reactions occurring in low-charge smectite with tetrahedral charge (beidellite). The lack of this information makes it difficult to predict the mobility of contaminants in environments where beidellite and major cations, which act as competitors with contaminants for sorption on the clay phase, are present. The present study proposes a multi-site ion exchange model able to describe experimental data obtained for H + and the four major cations (Na + , Ca 2+ , Mg 2+ and K + ) found in natural waters interacting with a <0.3 μm size fraction of Na-beidellite. The nature of the sites involved in the sorption processes is assessed using qualitative structural data. Moreover, the effect of the charge location in the smectite on the selectivity coefficient values is discussed by comparison with the results reported in the literature for smectite characterized by octahedral charge (montmorillonite). The new thermodynamic database proposed in this study is based on the same total sorption site density and distribution of sites regardless of the cations investigated. This database is valid for a large range of physico-chemical conditions: a [1–7] pH range, a total normality higher than 5 × 10 −3 mol/L corresponding to a flocculated state for water/clay systems, and when sorption of ions pairs can be neglected. Note that this study provides evidence that a thermodynamic database describing ion exchange reactions between H + and the four major cations of natural water for smectite cannot be valid irrespective of the total

  20. Treatment with selective serotonin reuptake inhibitors and mirtapazine results in differential brain activation by visual erotic stimuli in patients with major depressive disorder.

    Science.gov (United States)

    Kim, Won; Jin, Bo-Ra; Yang, Wan-Seok; Lee, Kyuong-Uk; Juh, Ra-Hyung; Ahn, Kook-Jin; Chung, Yong-An; Chae, Jeong-Ho

    2009-06-01

    The objective of this study was to identify patterns of brain activation elicited by erotic visual stimuli in patients treated with either Selective Serotonin Reuptake Inhibitors (SSRIs) or mirtazipine. Nine middle-aged men with major depressive disorder treated with an SSRI and ten middle-aged men with major depressive disorder treated with mirtazapine completed the trial. Ten subjects with no psychiatric illness were included as a control group. We conducted functional brain magnetic resonance imaging (fMRI) while a film alternatively played erotic and non-erotic contents for 14 minutes and 9 seconds. The control group showed activation in the occipitotemporal area, anterior cingulate gyrus, insula, orbitofrontal cortex, and caudate nucleus. For subjects treated with SSRIs, the intensity of activity in these regions was much lower compared to the control group. Intensity of activation in the group treated with mirtazapine was less than the control group but grea-ter than those treated with SSRIs. Using subtraction analysis, the SSRI group showed significantly lower activation than the mirtazapine group in the anterior cingulate gyrus and the caudate nucleus. Our study suggests that the different rates of sexual side effects between the patients in the SSRI-treated group and the mirtazapine-treated group may be due to different effects on brain activation.

  1. Atmospheric Extinction Coefficients in the Ic Band for Several Major International Observatories: Results from the BiSON Telescopes, 1984-2016

    Science.gov (United States)

    Hale, S. J.; Chaplin, W. J.; Davies, G. R.; Elsworth, Y. P.; Howe, R.; Lund, M. N.; Moxon, E. Z.; Thomas, A.; Pallé, P. L.; Rhodes, E. J., Jr.

    2017-09-01

    Over 30 years of solar data have been acquired by the Birmingham Solar Oscillations Network (BiSON), an international network of telescopes used to study oscillations of the Sun. Five of the six BiSON telescopes are located at major observatories. The observational sites are, in order of increasing longitude: Mount Wilson (Hale) Observatory (MWO), California, USA; Las Campanas Observatory, Chile; Observatorio del Teide, Izaña, Tenerife, Canary Islands; the South African Astronomical Observatory, Sutherland, South Africa; Carnarvon, Western Australia; and the Paul Wild Observatory, Narrabri, New South Wales, Australia. The BiSON data may be used to measure atmospheric extinction coefficients in the {{{I}}}{{c}} band (approximately 700-900 nm), and presented here are the derived atmospheric extinction coefficients from each site over the years 1984-2016.

  2. Towards a new classification of stable phase schizophrenia into major and simple neuro-cognitive psychosis: Results of unsupervised machine learning analysis.

    Science.gov (United States)

    Kanchanatawan, Buranee; Sriswasdi, Sira; Thika, Supaksorn; Stoyanov, Drozdstoy; Sirivichayakul, Sunee; Carvalho, André F; Geffard, Michel; Maes, Michael

    2018-05-23

    Deficit schizophrenia, as defined by the Schedule for Deficit Syndrome, may represent a distinct diagnostic class defined by neurocognitive impairments coupled with changes in IgA/IgM responses to tryptophan catabolites (TRYCATs). Adequate classifications should be based on supervised and unsupervised learning rather than on consensus criteria. This study used machine learning as means to provide a more accurate classification of patients with stable phase schizophrenia. We found that using negative symptoms as discriminatory variables, schizophrenia patients may be divided into two distinct classes modelled by (A) impairments in IgA/IgM responses to noxious and generally more protective tryptophan catabolites, (B) impairments in episodic and semantic memory, paired associative learning and false memory creation, and (C) psychotic, excitation, hostility, mannerism, negative, and affective symptoms. The first cluster shows increased negative, psychotic, excitation, hostility, mannerism, depression and anxiety symptoms, and more neuroimmune and cognitive disorders and is therefore called "major neurocognitive psychosis" (MNP). The second cluster, called "simple neurocognitive psychosis" (SNP) is discriminated from normal controls by the same features although the impairments are less well developed than in MNP. The latter is additionally externally validated by lowered quality of life, body mass (reflecting a leptosome body type), and education (reflecting lower cognitive reserve). Previous distinctions including "type 1" (positive)/"type 2" (negative) and DSM-IV-TR (eg, paranoid) schizophrenia could not be validated using machine learning techniques. Previous names of the illness, including schizophrenia, are not very adequate because they do not describe the features of the illness, namely, interrelated neuroimmune, cognitive, and clinical features. Stable-phase schizophrenia consists of 2 relevant qualitatively distinct categories or nosological entities with SNP

  3. Blind pre-analysis of the main building complex WWER-1000 Kozloduy. Comparison of analytical and experimental results obtained by explosive testing (task 8a of workplan 96/97)

    International Nuclear Information System (INIS)

    Krutzik, N.J.

    1999-01-01

    In accordance with the 96/97 workplan of the Research Programme on 'Benchmark Studies for Seismic Analysis and Testing of WWER-Type Nuclear Power Plants', blind pre analyses were prepared for the main building complex of the WWER-1000 based on given excitations derived from explosive tests. The investigations were performed by several institutions based on various mathematical models and procedures for consideration of soil-structure interaction effects, but on the same explosive test input data recently obtained. The methods of calculation and software tools used will also be different. The aim of this investigation is to validate different idealization concepts (mathematical models for the idealization of the structures and the soil) as well as investigation procedures (time domain and frequency domain analysis) and finally the software tools by comparing structural response results (time histories and response spectra). This report contains the results of the blind pre analysis performed by Siemens using an equivalent beam model of the main building of the WWER 1000. The calculations were performed by means of a frequency domain calculation

  4. Lifetime comorbidities between phobic disorders and major depression in Japan: results from the World Mental Health Japan 2002-2004 Survey.

    Science.gov (United States)

    Tsuchiya, Masao; Kawakami, Norito; Ono, Yutaka; Nakane, Yoshibumi; Nakamura, Yosikazu; Tachimori, Hisateru; Iwata, Noboru; Uda, Hidenori; Nakane, Hideyuki; Watanabe, Makoto; Naganuma, Yoichi; Furukawa, Toshiaki A; Hata, Yukihiro; Kobayashi, Masayo; Miyake, Yuko; Takeshima, Tadashi; Kikkawa, Takehiko; Kessler, Ronald C

    2009-01-01

    Although often considered of minor significance in themselves, evidence exists that early-onset phobic disorders might be predictors of later more serious disorders, such as major depressive disorder (MDD). The purpose of this study is to investigate the association of phobic disorders with the onset of MDD in the community in Japan. Data from the World Mental Health Japan 2002-2004 Survey were analyzed. A total of 2,436 community residents aged 20 and older were interviewed using the WHO Composite International Diagnostic Interview 3.0 (response rate, 58.4%). A Cox proportional hazard model was used to predict the onset of MDD as a function of prior history of DSM-IV specific phobia, agoraphobia, or social phobia, adjusting for gender, birth-cohort, other anxiety disorders, education, and marital status at survey. Social phobia was strongly associated with the subsequent onset of MDD (hazard ratio [HR]=4.1 [95% CI: 2.0-8.7]) after adjusting for sex, birth cohort, and the number of other anxiety disorders. The association between agoraphobia or specific phobia and MDD was not statistically significant after adjusting for these variables. Social phobia is a powerful predictor of the subsequent first onset of MDD in Japan. Although this finding argues against a simple neurobiological model and in favor of a model in which the cultural meanings of phobia play a part in promoting MDD, an elucidation of causal pathways will require more fine-grained comparative research.

  5. The TrialsTracker: Automated ongoing monitoring of failure to share clinical trial results by all major companies and research institutions.

    Science.gov (United States)

    Powell-Smith, Anna; Goldacre, Ben

    2016-01-01

    Background : Failure to publish trial results is a prevalent ethical breach with a negative impact on patient care. Audit is an important tool for quality improvement. We set out to produce an online resource that automatically identifies the sponsors with the best and worst record for failing to share trial results. Methods: A tool was produced that identifies all completed trials from clinicaltrials.gov, searches for results in the clinicaltrials.gov registry and on PubMed, and presents summary statistics for each sponsor online. Results : The TrialsTracker tool is now available. Results are consistent with previous publication bias cohort studies using manual searches. The prevalence of missing studies is presented for various classes of sponsor. All code and data is shared. Discussion: We have designed, built, and launched an easily accessible online service, the TrialsTracker, that identifies sponsors who have failed in their duty to make results of clinical trials available, and which can be maintained at low cost. Sponsors who wish to improve their performance metrics in this tool can do so by publishing the results of their trials.

  6. Regional assignment of seven genes on chromosome 1 of man by use of man-Chinese hamster somatic cell hybrids. II. Results obtained after induction of breaks in chromosome 1 by X-irradiation.

    Science.gov (United States)

    Burgerhout, W G; Smit, S L; Jongsma, A P

    1977-01-01

    The position of genes coding for PGD, PPH1, UGPP, GuK1, PGM1, Pep-C, and FH on human chromosome 1 was investigated by analysis of karyotype and enzyme phenotypes in man-Chinese hamster somatic cell hybrids carrying aberrations involving chromosome 1. Suitable hybrid cell lines were obtained by X-irradiation of hybrid cells carrying an intact chromosome 1 and by fusion of human cells from a clonal population carrying a translocation involving chromosome 1 with Chinese hamster cells. The latter human cell population had been isolated following X-irradiation of primary Lesch-Nyhan fibroblasts. In addition, products of de novo chromosome breakage in the investigated hybrid lines were utilized. By integrating the results of these analyses with earlier findings in our laboratory, the following positions of genes are deduced: PGD and PPH1 in 1p36 leads to 1p34; PGM1 in 1p32; UGPP in 1q21 leads to 1q23; GuK1 in 1q31 leads to 1q42; Pep-C in 1q42; and FH in 1qter leads to 1q42.

  7. The main characteristics of the Saclay proton synchrotron, and the results obtained at the time of its setting in operation; Les caracteristiques principales du synchrotron a protons de Saclay et les resultats obtenus lors de la mise en route

    Energy Technology Data Exchange (ETDEWEB)

    Bruck, H; Debraine, P; Levy-Mandel, R; Lutz, J; Maillet, R; Podliasky, I; Prevot, F; Taieb, J; Winter, S D [Commissariat a l' Energie Atomique, Saclay (France). Centre d' Etudes Nucleaires

    1958-07-01

    This paper consists on the one hand of a brief outline of the chief advantages of some characteristics peculiar to Saturne, particularly: the separation of the pole pieces from the body of the magnet, the structure of the vacuum chamber, the system of electrostatic deflectors of the injection optics and the HF cavity; and on the other hand of the difficulties encountered since starting up to improve the number of particles supplied by an induction electrode. The results obtained are also given, as for example the photographs taken in the propane chamber. (author)Fren. [French] La presente communication comporte d'une part un bref apercu des principaux avantages de quelques caracteristiques propres a Saturne et en particulier: la separation des pieces polaires de la masse de l'aimant, la structure de la chambre a vide, le systeme de deflecteurs electrostatiques de l'optique d'injection et la cavite HF; d'autre part, les difficultes rencontrees depuis la mise en route pour ameliorer le nombre de particules donne par une electrode d'induction, ainsi que les resultats obtenus comme par exemple les photographies prises dans la chambre a propane. (auteur)

  8. Employment status and health related quality of life among Hodgkin-lymphoma survivors'- results based on data from a major treatment center in Hungary.

    Science.gov (United States)

    Magyari, Ferenc; Kósa, Karolina; Berecz, Roland; Illés, Anna; Miltényi, Zsófia; Simon, Zsófia; Illés, Árpád

    2017-09-19

    Due to risk and response adapted treatment strategies, more than 80% of newly diagnosed classical Hodgkin lymphoma (HL) patients can be cured, and become long-term survivors. However, a high proportion of survivors suffer from treatment-related long-term side effects such as secondary malignancy, organ failure, persistent fatigue and psychological distress. The aim of this study was to evaluate psychological distress and its risk factors among our HL survivors. One hundred sixty-three (50% female) adult HL survivors were contacted between January 1, 2012 and march 31, 2015 in our outpatient centre. The patients were asked to complete a standardized, validated, self-administered Hungarian questionnaire with demographic questions and the following scales: Hospital anxiety and depression scale (HADS14), general health questionnaire (GHQ12), sense of coherence (SOC13) perceived stress scale (PSS4), dysfunctional attitude scale (DAS17). Disease and treatment data were acquired from hospital records. Majority of HL survivors are in early adulthood, our most important goal should be to return them to normal life after their lymphoma is cured. The employment status at the time of survey seemed to be crucial so patients were divided into either active (n = 93) or inactive (n = 47) group. Retired survivors (n = 19) were excluded from the subgroup analysis. Psychological distress was significantly lower in active patients. Multiple logistic regression analysis showed significant differences between the inactive and active subgroups, such as age at diagnosis (≥30 years or below, p = 0.001), education level (below college vs. college, p = 0.032) and treatment related long-term side effects (yes vs. no, p employment status and treatment-related long-term side effects play a critical role in the health related quality of life outcome among Hungarian HL survivors.

  9. The impact of exposure to interpersonal violence on gender differences in adolescent-onset major depression: results from the National Comorbidity Survey Replication (NCS-R).

    Science.gov (United States)

    Dunn, Erin C; Gilman, Stephen E; Willett, John B; Slopen, Natalie B; Molnar, Beth E

    2012-05-01

    Beginning in adolescence, females are at significantly higher risk for depression than males. Despite substantial efforts, gaps remain in our understanding of this disparity. This study tested whether gender differences in adolescent-onset depression arise because of female's greater exposure or sensitivity to violence. Data came from 5,692 participants in the National Comorbidity Survey Replication. Trained interviewers collected data about major depression and participants' exposure to four types of interpersonal violence (physical abuse, sexual assault, rape, and witnessing violence) using a modified version of the Composite International Diagnostic Interview. We used discrete time survival analysis to investigate gender differences in the risk of adolescent onset depression. Of the entire sample, 5.7% met DSM-IV criteria for depression by age 18; 5.8% of the sample reported being physically abused, 11.7% sexually assaulted, 8.5% raped, and 13.2% witnessed violence by age 18. Females had 1.51 times higher odds of depression by age 18 than males. Exposure to all types of violence was associated with an increased odds of depression in both the past year and the years following exposure. Adjusting for exposure to violence partially attenuated the association between gender and depression, especially for sexual assault (odds ratio [OR] attenuated = 1.28; 15.23%) and rape (OR attenuated = 1.32; 12.59%). There was no evidence that females were more vulnerable to the effects of violence than males. Gender differences in depression are partly explained by females' higher likelihood of experiencing interpersonal violence. Reducing exposure to sexual assault and rape could therefore mitigate gender differences in depression. © 2012 Wiley Periodicals, Inc.

  10. Reduced parahippocampal and lateral temporal GABA{sub A}-[{sup 11}C]flumazenil binding in major depression: preliminary results

    Energy Technology Data Exchange (ETDEWEB)

    Klumpers, Ursula M.H. [VU University Medical Center, Department of Psychiatry, Amsterdam (Netherlands); GGZ inGeest, partner of VUmc, Department of Psychiatry, Amsterdam (Netherlands); VU University Medical Center, Neuroscience Campus Amsterdam, Amsterdam (Netherlands); Veltman, Dick J. [VU University Medical Center, Department of Psychiatry, Amsterdam (Netherlands); VU University Medical Center, Neuroscience Campus Amsterdam, Amsterdam (Netherlands); Drent, Madeleine L. [VU University Medical Center, Department of Endocrinology, Amsterdam (Netherlands); Boellaard, Ronald; Lammertsma, Adriaan A. [VU University Medical Center, Department of Nuclear Medicine and PET Research, Amsterdam (Netherlands); VU University Medical Center, Neuroscience Campus Amsterdam, Amsterdam (Netherlands); Comans, Emile F.I. [VU University Medical Center, Department of Nuclear Medicine and PET Research, Amsterdam (Netherlands); Meynen, Gerben [VU University Medical Center, Department of Psychiatry, Amsterdam (Netherlands); Hoogendijk, Witte J.G. [VU University Medical Center, Department of Psychiatry, Amsterdam (Netherlands); VU University Medical Center, Center for Neurogenomics and Cognitive Research, Amsterdam (Netherlands); VU University Medical Center, Neuroscience Campus Amsterdam, Amsterdam (Netherlands)

    2010-03-15

    Major depressive disorder (MDD) has been related to both a dysfunctional {gamma}-amino butyric acid (GABA) system and to hyperactivity of the hypothalamic-pituitary-adrenal axis (HPA). Although GABA has been suggested to inhibit HPA axis activity, their relationship has never been studied at the level of the central GABA{sub A}-benzodiazepine receptor in depressed patients or in relation to antidepressant treatment. Eleven depressed outpatients were compared, before and after treatment with citalopram, with nine age-matched healthy controls. The subjects were scanned using the positron emission tomography (PET) tracer [{sup 11}C]flumazenil ([{sup 11}C]FMZ). Parametric voxel-by-voxel Logan plots were compared with methods based on regions of interest (ROI), to provide volume of distribution (V{sub T}) and binding potential (BP{sub ND}) values. Plasma GABA levels were determined and a dexamethasone-corticotropin releasing hormone (DEX-CRH) test was performed. In MDD, parametric voxel-by-voxel Logan plots showed bilateral reduced [{sup 11}C]FMZ binding in the parahippocampal gyrus and right lateral superior temporal gyrus (p uncorrected {<=}0.001). In the temporal area, [{sup 11}C]FMZ binding showed a strong inverse correlation with HPA axis activity. Plasma GABA did not discriminate MDD from controls, but correlated inversely with [{sup 11}C]FMZ binding in the right insula. Following treatment with citalopram, voxel-based analysis revealed reduced binding in the right lateral temporal gyrus and dorsolateral prefrontal cortex. The bilateral reduction in limbic parahippocampal and right temporal [{sup 11}C]FMZ binding found in MDD indicates decreased GABA{sub A}-benzodiazepine receptor complex affinity and/or number. The inverse relationship between GABA{sub A} binding in the temporal lobe and HPA axis activity, suggests that HPA axis hyperactivity is partly due to reduced GABA-ergic inhibition. (orig.)

  11. Prevalence and correlates of major depressive disorder and dysthymia in an eleven-year follow-up--results from the Finnish Health 2011 Survey.

    Science.gov (United States)

    Markkula, Niina; Suvisaari, Jaana; Saarni, Samuli I; Pirkola, Sami; Peña, Sebastian; Saarni, Suoma; Ahola, Kirsi; Mattila, Aino K; Viertiö, Satu; Strehle, Jens; Koskinen, Seppo; Härkänen, Tommi

    2015-03-01

    Up-to-date epidemiological data on depressive disorders is needed to understand changes in population health and health care utilization. This study aims to assess the prevalence of major depressive disorder (MDD) and dysthymia in the Finnish population and possible changes during the past 11 years. In a nationally representative sample of Finns aged 30 and above (BRIF8901), depressive disorders were diagnosed with the Composite International Diagnostic Interview (M-CIDI) in 2000 and 2011. To account for nonresponse, two methods were compared: multiple imputation (MI) utilizing data from the hospital discharge register and from the interview in 2000 and statistical weighting. The MI-corrected 12-month prevalence of MDD was 7.4% (95% CI 5.7-9.0) and of dysthymia was 4.5% (95% CI 3.1-5.9), whereas the corresponding figures using weights were 5.4% (95% CI 4.7-6.1) for MDD and 2.0% (95% CI 1.6-2.4) for dysthymia. Women (OR 2.33, 95% CI 1.6-3.4) and unmarried people (OR 1.54, 95% CI 1.2-2.0) had a higher risk of depressive disorders. There was a significant increase in the prevalence of depressive disorders during the follow-up period from 7.3% in 2000 to 9.6% in 2011. Prevalences were two percentage points higher, on average, when using MI compared to weighting. Hospital treatments for depressive disorders and other mental disorders were strongly associated with nonparticipation. The CIDI response rate dropped from 75% in 2000 to 57% in 2011, but this was accounted for by MI and weighting. Depressive disorders are a growing public health concern in Finland. Non-participation of persons with severe mental disorders may bias the prevalence estimates of mental disorders in population-based studies. Copyright © 2014 Elsevier B.V. All rights reserved.

  12. Comorbid thyroid disease in patients with major depressive disorder - results from the European Group for the Study of Resistant Depression (GSRD).

    Science.gov (United States)

    Fugger, Gernot; Dold, Markus; Bartova, Lucie; Kautzky, Alexander; Souery, Daniel; Mendlewicz, Julien; Serretti, Alessandro; Zohar, Joseph; Montgomery, Stuart; Frey, Richard; Kasper, Siegfried

    2018-06-01

    This multicenter study of the European Group for the Study of Resistant Depression (GSRD) aimed to explore the association between major depressive disorder (MDD) and comorbid thyroid disease. A total number of 1410 patients` characteristics in terms of demographic and clinical information were compared between MDD subjects with and without concurrent thyroid disease using descriptive statistics, analyses of covariance (ANCOVA) and binary logistic regression analyses. We determined a point prevalence rate for comorbid hypothyroidism of 13.2% and 1.6% for comorbid hyperthyroidism respectively. Patients with MDD+comorbid hypothyroidism were significantly older, more likely to be female, inpatient and suffering from other comorbid chronic somatic conditions. Furthermore, MADRS score at onset of the current depressive episode was significantly higher, psychotic features of depression were more likely pronounced. Overall, patients in the MDD+comorbid hypothyroidism group were rather treated with a combination of drugs, for example, pregabalin, antipsychotic drugs and mood stabilizers. In the MDD+comorbid hyperthyroidism group patients were significantly older, of Caucasian origin and diagnosed with other somatic comorbidities. In conclusion, our analyses suggest that abnormal thyroid function, especially hypothyroidism, is linked to depression severity and associated with distinct psychopathologic features of depression. However, comorbid thyroid disease has no influence on treatment response. A combination or augmentation of psychopharmacological drugs, especially with antipsychotics, mood stabilizers and pregabalin is more likely in patients with hypothyroid conditions. Thyroid disorder is frequently found in combination with other chronic somatic diseases including hypertension and heart disease. Copyright © 2018 Elsevier B.V. and ECNP. All rights reserved.

  13. COGNITION-CHILDHOOD MALTREATMENT INTERACTIONS IN THE PREDICTION OF ANTIDEPRESSANT OUTCOMES IN MAJOR DEPRESSIVE DISORDER PATIENTS: RESULTS FROM THE iSPOT-D TRIAL.

    Science.gov (United States)

    Miller, Shefali; McTeague, Lisa M; Gyurak, Anett; Patenaude, Brian; Williams, Leanne M; Grieve, Stuart M; Korgaonkar, Mayuresh S; Etkin, Amit

    2015-08-01

    Childhood maltreatment (CM) history has been associated with poor treatment response in major depressive disorder (MDD), but the mechanisms underlying this relationship remain opaque. Dysfunction in the neural circuits for executive cognition is a putative neurobiological consequence of CM that may contribute importantly to adverse clinical outcomes. We used behavioral and neuroimaging measures of executive functioning to assess their contribution to the relationship between CM and antidepressant response in MDD patients. Ninety eight medication-free MDD outpatients participating in the International Study to Predict Optimized Treatment in Depression were assessed at baseline on behavioral neurocognitive measures and functional magnetic resonance imaging during tasks probing working memory (continuous performance task, CPT) and inhibition (Go/No-go). Seventy seven patients completed 8 weeks of antidepressant treatment. Baseline behavioral and neuroimaging measures were assessed in relation to CM (history of childhood physical, sexual, and/or emotional abuse) and posttreatment depression outcomes. Patients with maltreatment exhibited decreased modulation of right dorsolateral prefrontal cortex (DLPFC) activity during working memory updating on the CPT, and a corresponding impairment in CPT behavioral performance outside the scanner. No between-group differences were found for imaging or behavior on the Go/No-go test of inhibition. Greater DLPFC activity during CPT significantly predicted posttreatment symptom improvement in patients without maltreatment, whereas the relationship between DLPFC activity and symptom change was nonsignificant, and in the opposite direction, in patients with maltreatment. The effect of CM on prefrontal circuitry involved in executive function is a potential predictor of antidepressant outcomes. © 2015 Wiley Periodicals, Inc.

  14. Resultados del LASIK miópico en el Instituto Cubano de Oftalmología "Ramón Pando Ferrer" Results of myopic LASIK obtained at “Ramón Pando Ferrer” Cuban Institute of Ophthalmology

    Directory of Open Access Journals (Sweden)

    Isabel Cristina Lantigua Maldonado

    2012-06-01

    Full Text Available Objetivos: Evaluar los resultados y la estabilidad del LASIK miópico realizado en el Instituto Cubano de Oftalmología "Ramón Pando Ferrer". Métodos: Se realizó un estudio descriptivo, prospectivo y comparativo. El universo estuvo compuesto por los pacientes operados mediante LASIK (4 011 ojos desde el inicio en nuestro centro (2005 de la cirugía refractiva corneal con láser de excímeros. Se seleccionaron los pacientes con estudios realizados un año después de la cirugía. Las variables estudiadas fueron queratometría, mejor agudeza visual sin corrección, mejor agudeza visual con corrección, equivalente esférico, paquimetría y topografía. Se compararon las variables antes de la cirugía y al año de esta. Los resultados se analizaron mediante la prueba t de Student para datos pareados con significación estadística cuando pObjective: To evaluate the results and the stability of the myopic Lasik carried out in “Ramón Pando Ferrer” Cuban Institute of Ophthalmology. Methods: A prospective, descriptive and comparative study was conducted. The universe of study was made up of the patients operated on by LASIK (4011 eyes from the beginning of the corneal refractive surgery with excimer laser in our center in 2005. The patients were selected from those that had been studied for ametropy correction one year after the surgery. The studied variables were keratometry, better visual acuity without correction, better visual acuity with correction, spherical equivalent, pachymetry and topography, and the obtained results were compared before and at one year of the surgery. The paired T test served to analyze the results with statistical significance of p < 0.05. Results: Significant changes took place in keratometry and spherical equivalent that brought about improved visual acuity without correction for distance vision. The best visual acuity with correction remained the same before and after the surgery. Pachymetry remained within safe

  15. Syntax Score and Major Adverse Cardiac Events in Patients with Suspected Coronary Artery Disease: Results from a Cohort Study in a University-Affiliated Hospital in Southern Brazil.

    Science.gov (United States)

    Fuchs, Felipe C; Ribeiro, Jorge P; Fuchs, Flávio D; Wainstein, Marco V; Bergoli, Luis C; Wainstein, Rodrigo V; Zen, Vanessa; Kerkhoff, Alessandra C; Moreira, Leila B; Fuchs, Sandra C

    2016-09-01

    The importance of coronary anatomy in predicting cardiovascular events is well known. The use of traditional anatomical scores in routine angiography, however, has not been incorporated to clinical practice. SYNTAX score (SXscore) is a scoring system that estimates the anatomical extent of coronary artery disease (CAD). Its ability to predict outcomes based on a baseline diagnostic angiography has not been tested to date. To evaluate the performance of the SXscore in predicting major adverse cardiac events (MACE) in patients referred for diagnostic angiography. Prospective cohort of 895 patients with suspected CAD referred for elective diagnostic coronary angiography from 2008 to 2011, at a university-affiliated hospital in Brazil. They had their SXscores calculated and were stratified in three categories: no significant CAD (n = 495), SXscoreLOW-INTERMEDIATE: prospectiva de 895 pacientes com suspeita de DAC encaminhados para cineangiocoronariografia diagnóstica eletiva de 2008 a 2011, em hospital universitário no Brasil. Os pacientes tiveram seus SXescores calculados e foram estratificados em três categorias: 'sem DAC significativa' (n = 495); SXescoreBAIXO-INTERMEDIÁRIO: < 23 (n = 346); e SXescoreALTO: ≥ 23 (n = 54). O desfecho primário foi composto de morte cardíaca, infarto do miocárdio e revascularização tardia. Os desfechos secundários foram MACE e morte por todas as causas. Em média, os pacientes foram acompanhados por 1,8 ± 1,4 anos. Desfecho primário ocorreu em 2,2%, 15,3% e 20,4% nos grupos 'sem DAC significativa', SXescoreBAIXO-INTERMEDIÁRIO e SXescoreALTO, respectivamente (p < 0,001). Morte por todas as causas foi significativamente mais frequente no grupo de SXescoreALTO comparado ao grupo 'sem DAC significativa', 16,7% e 3,8% (p < 0,001), respectivamente. Após ajuste para fatores de confusão, todos os desfechos permaneceram associados com o SXescore. O SXescore prediz independentemente MACE em pacientes submetidos a

  16. Single i.v. ketamine augmentation of newly initiated escitalopram for major depression: results from a randomized, placebo-controlled 4-week study.

    Science.gov (United States)

    Hu, Y-D; Xiang, Y-T; Fang, J-X; Zu, S; Sha, S; Shi, H; Ungvari, G S; Correll, C U; Chiu, H F K; Xue, Y; Tian, T-F; Wu, A-S; Ma, X; Wang, G

    2016-02-01

    While oral antidepressants reach efficacy after weeks, single-dose intravenous (i.v.) ketamine has rapid, yet time-limited antidepressant effects. We aimed to determine the efficacy and safety of single-dose i.v. ketamine augmentation of escitalopram in major depressive disorder (MDD). Thirty outpatients with severe MDD (17-item Hamilton Rating Scale for Depression total score ⩾ 24) were randomized to 4 weeks double-blind treatment with escitalopram 10 mg/day+single-dose i.v. ketamine (0.5 mg/kg over 40 min) or escitalopram 10 mg/day + placebo (0.9% i.v. saline). Depressive symptoms were measured using the Montgomery-Asberg Depression Rating Scale (MADRS) and the Quick Inventory of Depressive Symptomatology - Self-Report (QIDS-SR). Suicidal ideation was evaluated with the QIDS-SR item 12. Adverse psychopathological effects were measured with the Brief Psychiatric Rating Scale (BPRS)-positive symptoms, Young Mania Rating Scale (YMRS) and Clinician Administered Dissociative States Scale (CADSS). Patients were assessed at baseline, 1, 2, 4, 24 and 72 h and 7, 14, 21 and 28 days. Time to response (⩾ 50% MADRS score reduction) was the primary outcome. By 4 weeks, more escitalopram + ketamine-treated than escitalopram + placebo-treated patients responded (92.3% v. 57.1%, p = 0.04) and remitted (76.9% v. 14.3%, p = 0.001), with significantly shorter time to response [hazard ratio (HR) 0.04, 95% confidence interval (CI) 0.01-0.22, p escitalopram + placebo, escitalopram + ketamine was associated with significantly lower MADRS scores from 2 h to 2 weeks [(peak = 3 days-2 weeks; effect size (ES) = 1.08-1.18)], QIDS-SR scores from 2 h to 2 weeks (maximum ES = 1.27), and QIDS-SR suicidality from 2 to 72 h (maximum ES = 2.24). Only YMRS scores increased significantly with ketamine augmentation (1 and 2 h), without significant BPRS or CADSS elevation. Single-dose i.v. ketamine augmentation of escitalopram was safe and effective in severe MDD, holding promise for speeding up

  17. Non-energy use of fossil fuels and resulting carbon dioxide emissions: bottom-up estimates for the world as a whole and for major developing countries

    NARCIS (Netherlands)

    Weiss, M.; Neelis, M.L.; Blok, K.; Patel, M.K.

    2009-01-01

    We present and apply a simple bottom–up model for estimating non-energy use of fossil fuels and resulting CO2 (carbon dioxide) emissions.We apply this model for the year 2000: (1) to the world as a whole, (2) to the aggregate of Annex I countries and non-Annex I countries, and (3) to the ten

  18. Theoretical impacts of a range of major tobacco retail outlet reduction interventions: modelling results in a country with a smoke-free nation goal.

    Science.gov (United States)

    Pearson, Amber L; van der Deen, Frederieke S; Wilson, Nick; Cobiac, Linda; Blakely, Tony

    2015-03-01

    To inform endgame strategies in tobacco control, this study aimed to estimate the impact of interventions that markedly reduced availability of tobacco retail outlets. The setting was New Zealand, a developed nation where the government has a smoke-free nation goal in 2025. Various legally mandated reductions in outlets that were phased in over 10 years were modelled. Geographic analyses using the road network were used to estimate the distance and time travelled from centres of small areas to the reduced number of tobacco outlets, and from there to calculate increased travel costs for each intervention. Age-specific price elasticities of demand were used to estimate future smoking prevalence. With a law that required a 95% reduction in outlets, the cost of a pack of 20 cigarettes (including travel costs) increased by 20% in rural areas and 10% elsewhere and yielded a smoking prevalence of 9.6% by 2025 (compared with 9.9% with no intervention). The intervention that permitted tobacco sales at only 50% of liquor stores resulted in the largest cost increase (∼$60/pack in rural areas) and the lowest prevalence (9.1%) by 2025. Elimination of outlets within 2 km of schools produced a smoking prevalence of 9.3%. This modelling merges geographic, economic and epidemiological methodologies in a novel way, but the results should be interpreted cautiously and further research is desirable. Nevertheless, the results still suggest that tobacco outlet reduction interventions could modestly contribute to an endgame goal. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://group.bmj.com/group/rights-licensing/permissions.

  19. Telephone based cognitive behavioral therapy targeting major depression among urban dwelling, low income people living with HIV/AIDS: results of a randomized controlled trial.

    Science.gov (United States)

    Himelhoch, Seth; Medoff, Deborah; Maxfield, Jennifer; Dihmes, Sarah; Dixon, Lisa; Robinson, Charles; Potts, Wendy; Mohr, David C

    2013-10-01

    This pilot randomized controlled trial evaluated a previously developed manualized telephone based cognitive behavioral therapy (T-CBT) intervention compared to face-to-face (f2f) therapy among low-income, urban dwelling HIV infected depressed individuals. The primary outcome was the reduction of depressive symptoms as measured by the Hamliton rating scale for depression scale. The secondary outcome was adherence to HAART as measured by random telephone based pill counts. Outcome measures were collected by trained research assistants masked to treatment allocation. Analysis was based on intention-to-treat. Thirty-four participants met eligibility criteria and were randomly assigned to receive T-CBT (n = 16) or f2f (n = 18). There was no statistically significant difference in depression treatment outcomes comparing f2f to T-CBT. Within group evaluation demonstrated that both the T-CBT and the f2f psychotherapy groups resulted in significant reductions in depressive symptoms. Those who received the T-CBT were significantly more likely to maintain their adherence to antiretroviral medication compared to the f2f treatment. None of the participants discontinued treatment due to adverse events. T-CBT can be delivered to low-income, urban dwelling HIV infected depressed individuals resulting in significant reductions in depression symptoms and improved adherence to antiretroviral medication. Clinical Trial.gov identifier: NCT01055158.

  20. Contribution of the calving interval to dairy farm profitability: results of a cluster analysis of FADN data for a major milk production area in southern Italy

    Directory of Open Access Journals (Sweden)

    G. Dono

    2013-10-01

    Full Text Available In this study we investigated the potential economic impact of good management of the calving interval on dairy farms. This involved the assessment of economics and production of a sample of farms, selected from the Farm Accountancy Data Network (FADN, and located in Sardinia, Italy. Two farm models were derived from clustering the sample by k-means, which were validated by verifying their consistency in relation to nutritional needs, feed supply and milk production of the herds. Differences in indices of performance and dynamics were found (e.g. ROE is -0.8% vs 4.7%, with evident linkages between economic performance, greater efficiency, reproductive capacity, and potential turnover. The model better performing reflected greater economic feeding efficiency and a shorter calving interval. Hence, management, more than structural aspects, determined the economic results of the sampled farms.

  1. Oxidative stress and antioxidant parameters in patients with major depressive disorder compared to healthy controls before and after antidepressant treatment: results from a meta-analysis.

    Science.gov (United States)

    Jiménez-Fernández, Sara; Gurpegui, Manuel; Díaz-Atienza, Francisco; Pérez-Costillas, Lucía; Gerstenberg, Miriam; Correll, Christoph U

    2015-12-01

    To investigate the role of oxidative stress and antioxidants in depression. We searched the literature without language restrictions through MEDLINE/PubMed, Cochrane Library, Fisterra, and Galenicom from database inception until December 31, 2013, supplemented by a hand search of relevant articles. Search terms included (1) oxidative stress, antioxidant*, nitrosative stress, nitrative stress, nitro-oxidative stress, free radical*, and names of individual oxidative stress markers/antioxidants and (2) depression and related disorders and antidepressant. Included were studies in patients with depression comparing antioxidant or oxidative stress markers with those in healthy controls before and after antidepressant treatment. Two authors independently extracted the data for antioxidant or oxidative stress markers. Standardized mean differences (SMDs) ± 95% confidence intervals (CIs) for results from ≥ 3 studies were calculated. Altogether, 29 studies (N = 3,961; patients with depression = 2,477, healthy controls = 1,484) reported on the oxidative stress marker malondialdehyde (MDA) and total nitrites, the antioxidants uric acid and zinc, or the antioxidant-enhancing enzymes superoxide dismutase (SOD), catalase (CAT), and glutathione peroxidase (GPX). When patients with depression were compared with healthy controls, depression was associated with higher oxidative stress MDA levels (8 studies; n = 916; SMD = 1.34; 95% CI, 0.57 to 2.11; P Depression Rating Scale scores (24.6 ± 0.7 to 16.2 ± 1.6; SMD = 2.65; 95% CI, 1.13 to 4.15; P = .00065), reduced MDA (4 studies; n = 194; SMD = -1.45; 95% CI, -2.43 to -0.47; P = .004) and increased uric acid (3 studies; n = 212; SMD = 0.76; 95% CI, 0.03 to 1.49; P = .040) and zinc levels (3 studies; n = 65; SMD = 1.22; 95% CI, 0.40 to 2.04, P = .004), without differences in MDA (P = .60), uric acid (P = .10), and zinc (P = .163) levels compared to healthy controls. Results suggest that oxidative stress plays a role in depression

  2. PRELIMINARY RESULTS OF ATMOSPHERIC DEPOSITION OF MAJOR AND TRACE ELEMENTS IN THE GREATER AND LESSER CAUCASUS MOUNTAINS STUDIED BY THE MOSS TECHNIQUE AND NEUTRON ACTIVATION ANALYSIS

    Directory of Open Access Journals (Sweden)

    S. Shetekauri

    2015-05-01

    Full Text Available The method of moss biomonitoring of atmospheric deposition of trace elements was applied for the first time in the western Caucasus Mountains to assess the environmental situation in this region. The sixteen moss samples have been collected in 2014 summer growth period along altitudinal gradients in the range of altitudes from 600 m to 2665 m. Concentrations of Na, Mg, Al, Cl, K, Ca, Ti, V, Mn, Fe, Zn, As, Br, Rb, Mo, Cd, I, Sb, Ba, La, Sm, W, Au, and U determined by neutron activation analysis in the moss samples are reported. A comparison with the data for moss collected in Norway (pristine area was carried out.  Multivariate statistical analysis of the results was used for assessment pollution sources in the studied part of the Caucasus. The increase in concentrations of most of elements with rising altitude due to gradually disappearing vegetation cover and wind erosion of soil was observed. A comparison with the available data for moss collected in the Alps at the same altitude (~ 2500 m was performed.

  3. [Sociology as a Major Factor for the Psychiatrie-Enquete in the Federal Republic of Germany - Results from Expert Interviews and Document Analyses].

    Science.gov (United States)

    Söhner, Felicitas; Fangerau, Heiner; Becker, Thomas

    2018-05-01

    This paper examines the influence of sociology as a discipline on the Psychiatrie-Enquete by analysing interviews with expert (psychiatrist, psychologist, sociologist etc.) witnesses of the Enquete process and by analysing pertinent documents. 24 interviews were conducted and analysed using qualitative secondary analysis. Sociological texts and research results influenced the professional development of psychiatrists at the time. Cross-talk between psychiatry and sociology developed through seminal sociological analyses of psychiatric institutions and the interest taken in medical institutions in a number of sociological texts. Inter-disciplinary joint studies (of sociologists and psychiatrists) affected the research interest and professional behaviour of psychiatrists involved in the process on the way to the Psychiatrie-Enquete. Tenacity of psychiatrists' systems of opinion was dissolved by impulses from the sociological thought community. The forms of contact between the psychiatric and the sociological thought collective which we could reconstruct are an example of the evolution of knowledge and practice through transdisciplinary communication. © Georg Thieme Verlag KG Stuttgart · New York.

  4. [Using social network analysis to examine care for older drug users in three major cities in Germany : Results of a pilot study].

    Science.gov (United States)

    Kuhn, U; Hofmann, L; Hoff, T; Färber, N

    2018-05-04

    Compared with the general population, chronic drug addicts already start showing typical aging problems by the age of 40 years. The increasing number of older drug addicts leads to questions of what an adequate health and social care should look like. This discussion particularly takes place in the context of a sufficient integration of different care systems. A sufficient integration requires an improvement in the networking of substance treatment, nursing care and medical care services. The purpose of this study was to investigate the care structure of older people who use drugs and the services involved in a social network analysis. This was a descriptive design of the pilot study. The study objective was to gain first-hand knowledge about the health and social care situation, the quality of care concerning this client group and to identify supply gaps. Therefore, the three regions Cologne, Dusseldorf and Frankfurt/Main were exemplarily examined. The data for the social network analysis was gathered by a quantitative online questionnaire. Therefore, especially central network members were contacted and asked to participate. The survey was conducted in two waves. In total, 65 practitioners of all surveyed cities participated in the second wave. The centrality measures assessed indicated that in all regions institutions of the substance abuse service network hold central positions in terms of conveying information. The moderate density values of the networks suggest that there are sufficient cooperation structures. Care deficits were identified most frequently in the areas of housing and nursing care. The results provide the first systematic insights and a description of the cooperation practice in the care system. Because of the limitations, further research and practice issues are raised.

  5. Silencing of the major family of NBS-LRR-encoding genes in lettuce results in the loss of multiple resistance specificities.

    Science.gov (United States)

    Wroblewski, Tadeusz; Piskurewicz, Urszula; Tomczak, Anna; Ochoa, Oswaldo; Michelmore, Richard W

    2007-09-01

    The RGC2 gene cluster in lettuce (Lactuca sativa) is one of the largest known families of genes encoding nucleotide binding site-leucine-rich repeat (NBS-LRR) proteins. One of its members, RGC2B, encodes Dm3 which determines resistance to downy mildew caused by the oomycete Bremia lactucae carrying the cognate avirulence gene, Avr3. We developed an efficient strategy for analysis of this large family of low expressed genes using post-transcriptional gene silencing (PTGS). We transformed lettuce cv. Diana (carrying Dm3) using chimeric gene constructs designed to simultaneously silence RGC2B and the GUS reporter gene via the production of interfering hairpin RNA (ihpRNA). Transient assays of GUS expression in leaves accurately predicted silencing of both genes and were subsequently used to assay silencing in transgenic T(1) plants and their offspring. Levels of mRNA were reduced not only for RGC2B but also for all seven diverse RGC2 family members tested. We then used the same strategy to show that the resistance specificity encoded by the genetically defined Dm18 locus in lettuce cv. Mariska is the result of two resistance specificities, only one of which was silenced by ihpRNA derived from RGC2B. Analysis of progeny from crosses between transgenic, silenced tester stocks and lettuce accessions carrying other resistance genes previously mapped to the RGC2 locus indicated that two additional resistance specificities to B. lactucae, Dm14 and Dm16, as well as resistance to lettuce root aphid (Pemphigus bursarius L.), Ra, are encoded by RGC2 family members.

  6. Comparison of 230Th/234U Dating Results Obtained on Fossil Mollusk Shell from Morocco and Fossil Coral Samples from Egypt. Research of Methodological Criteria to Valid the Measured Age

    International Nuclear Information System (INIS)

    Choukri, A.; Hakam, O.K.; Reyss, J.L.

    2013-01-01

    Radiochemical ages of 126 unrecrystallized coral samples from the Egyptian shoreline and 125 fossil mollusk shell samples from the Atlantic coast of Moroccan High Atlas are discussed.For corals, the obtained ages are in good agreement with the ages reported previously on urecristallized corals except in some sites where some samples are affected by a cementation of younger aragonite.For mollusk shells, the obtained ages are in the most of cases, rejuvenated.This rejuvenation is due eventually to a post-incorporation of secondary uranium that is responsible of the wide dispersion of apparent ages of mollusk shells.

  7. Programs to obtain vertical heights from mean sea level and for computing volume of sand/mineral along beaches: A case study with Kalbadevi beach profiling data and results

    Digital Repository Service at National Institute of Oceanography (India)

    Ganesan, P.

    Two programs have been developed to process profile data, for obtaining vertical heights with respect to mean sea level (M.S.L.) and for computation of volume of heavy mineral / sand accumulation or erosion along the beaches. The final output...

  8. Windmills: selection method and results obtained by the Renewable Energy Center of UNESP - Guaratingueta Campus, Sao Paulo state, Brazil; Cata-vento: metodo de selecao e resultados obtidos pelo Centro de Energias Renovaveis da UNESP - Campus Guaratingueta

    Energy Technology Data Exchange (ETDEWEB)

    Moura, Luis Fernando Silva; Souza, Teofilo Miguel de [Universidade Estadual Paulista (UNESP), Guaratingueta, SP (Brazil). Centro de Energias Renovaveis], e-mail: teofilo@feg.unesp.br, e-mail: lfernandosm@uol.com.br

    2004-07-01

    Windmills are always a good option to promote irrigate in areas with adequate potential wind. Its correct selection can guarantee the enough water supply with minimum cost. Since April 2004 the Renewable Energy Center of UNESP - Campus Guaratingueta' has tested a commercial windmill with 18 blades rotor and 3,4 diameter meters, that in a area with approximately 3 m/s average wind speed, has been obtained a average daily 1500 water liters. This volume is enough to supply a small country state, however, it could be get with a smaller capacity machine, if this worked properly. (author)

  9. Preliminary Results Obtained from Flight Test of a 1/7-Scale Rocket-Powered Model of the Grumman XF10F Airplane Configuration in the Swept-Wing Condition, TED No. NACA DE 354

    Science.gov (United States)

    Gardner, William N.

    1951-01-01

    A flight investigation of a 1/7-scale rocket-powered model of the XF10F Grumman XFl0F airplane in the swept-wing configuration has been made. The purpose of this test was to determine the static longitudinal stability, damping in pitch, and longitudinal control effectiveness of the airplane with the center of gravity at 20 percent of the wing mean aerodynamic chord. Only a small amount of data was obtained from the test because, immediately after booster separation at a Mach number of 0.88, the configuration was directionally unstable and diverged in sideslip. Simultaneous with the sideslip divergence, the model became longitudinally unstable at 3 degree angle of attack and -6 degree sideslip and diverged in pitch to a high angle of attack. During the pitch-up the free-floating horizontal tail became unstable at 5 degree angle of attack and the tail drifted against its positive deflection limit.

  10. Results of environmental radiation monitoring and meteorology measurements (material prepared for obtaining the licence for RA reactor experimental operation); Rezultati merenja zracenja u okolini i rezultati meteoroloskih merenja (materijal pripremljen radi dobijanja dozvole za pustanje Reaktora RA u probni rad)

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1980-10-15

    According to the demands for obtaining the licence for restarting the Ra reactor and the experimental operation this document includes the radiation monitoring measured data in the working space and environment of the RA reactor, i.e. Boris Kidric Institute. The meteorology measured data are included as well. All the measurements are performed according to the radiation protection program applied actually from the first reactor start-up at the end of 1959. [Serbo-Croat] Saglasno zahtevu za dobijanje dozvole za ponovno pustanje u probni rad reaktora RA, ovaj dokument sadrzi rezultate merenja zracenja u okolini (radnoj i zivotnoj) reaktora RA odnosno instituta 'Boris Kidric' kao i podatke o meteoroloskim merenjima. Sve merenja rade se prema programu mera zastite od zracenja koje se sprovode prakticno od prvog pustanja reaktora u rad krajem 1959. godine.

  11. Application of Molecular Typing Results in Source Attribution Models: The Case of Multiple Locus Variable Number Tandem Repeat Analysis (MLVA) of Salmonella Isolates Obtained from Integrated Surveillance in Denmark

    DEFF Research Database (Denmark)

    de Knegt, Leonardo; Pires, Sara Monteiro; Löfström, Charlotta

    2016-01-01

    , and antibiotic resistance profiles for the Salmonella source attribution, and assess the utility of the results for the food safety decisionmakers. Full and simplified MLVA schemes from surveillance data were tested, and model fit and consistency of results were assessed using statistical measures. We conclude...

  12. Different percentages of false-positive results obtained using five methods for the calculation of reference change values based on simulated normal and ln-normal distributions of data

    DEFF Research Database (Denmark)

    Lund, Flemming; Petersen, Per Hyltoft; Fraser, Callum G

    2016-01-01

    a homeostatic set point that follows a normal (Gaussian) distribution. This set point (or baseline in steady-state) should be estimated from a set of previous samples, but, in practice, decisions based on reference change value are often based on only two consecutive results. The original reference change value......-positive results. The aim of this study was to investigate false-positive results using five different published methods for calculation of reference change value. METHODS: The five reference change value methods were examined using normally and ln-normally distributed simulated data. RESULTS: One method performed...... best in approaching the theoretical false-positive percentages on normally distributed data and another method performed best on ln-normally distributed data. The commonly used reference change value method based on two results (without use of estimated set point) performed worst both on normally...

  13. Analysis of positive control STR experiments reveals that results obtained for FGA, D3S1358, and D13S317 condition the success rate of the analysis of routine reference samples.

    Science.gov (United States)

    Murigneux, Valentine; Dufour, Anne-Béatrice; Lobry, Jean R; Pène, Laurent

    2014-07-01

    About 120,000 reference samples are analyzed each year in the Forensic Laboratory of Lyon. A total of 1640 positive control experiments used to validate and optimize the analytical method in the routine process were submitted to a multivariate exploratory data analysis approach with the aim of better understanding the underlying sources of variability. The peak heights of the 16 genetic markers targeted by the AmpFℓSTR(®) Identifiler(®) STR kit were used as variables of interest. Six different 3130xl genetic analyzers located in the same controlled environment were involved. Two major sources of variability were found: (i) the DNA load of the sample modulates all peak heights in a similar way so that the 16 markers are highly correlated, (ii) the genetic analyzer used with a locus-specific response for peak height and a better sensitivity for the most recently acquired. Three markers (FGA, D3S1358, and D13S317) were found to be of special interest to predict the success rate observed in the routine process. © 2014 American Academy of Forensic Sciences.

  14. Geopolymer obtained from coal ash

    International Nuclear Information System (INIS)

    Conte, V.; Bissari, E.S.; Uggioni, E.; Bernardin, A.M.

    2011-01-01

    Geopolymers are three-dimensional alumino silicates that can be rapidly formed at low temperature from naturally occurring aluminosilicates with a structure similar to zeolites. In this work coal ash (Tractebel Energy) was used as source of aluminosilicate according a full factorial design in eight formulations with three factors (hydroxide type and concentration and temperature) and two-levels. The ash was dried and hydroxide was added according type and concentration. The geopolymer was poured into cylindrical molds, cured (14 days) and subjected to compression test. The coal ash from power plants belongs to the Si-Al system and thus can easily form geopolymers. The compression tests showed that it is possible to obtain samples with strength comparable to conventional Portland cement. As a result, temperature and molarity are the main factors affecting the compressive strength of the obtained geopolymer. (author)

  15. Obtaining and analysis of results of fatigue and corrosion-fatigue in steel API 5L X60; Obtencao e analise de resultados de fadiga e corrosao-fadiga em aco API 5L X60

    Energy Technology Data Exchange (ETDEWEB)

    Araujo, Bruno Allison [Universidade Federal de Campina Grande (UFCG), PB (Brazil). Programa de Pos-Graduacao em Ciencia e Engenharia de Materiais; Silva, Antonio Almeida; Santos, Fabio Gualberto Chagas [Universidade Federal de Campina Grande (UFCG), PB (Brazil)

    2008-07-01

    The corrosion process allied to the fatigue, due to repetitive efforts of several natures, is the main responsible for the damages in pipeline and offshore structures that results in the appears of located faults, and by the way can results in leaks and financial and environmental loss. This phenomenon calls corrosion-fatigue, however, it is very complex, and mainly, in what it concerns the form as this it develops in the structure. The objective of this work is to present some results of experimental fatigue tests and corrosion-fatigue accomplished with specimen that the material originated a pipeline steel API 5L X60. The tests developed in a machine which could test until 12 specimens per time. For test of corrosion-fatigue was used a cell-of-corrosion especially projected, in this way simulated an aggressive environmental condition in a corrosion conditions. With the results of tests, was possible estimate the fatigue limits of the specimen when submitted to the repeated flexing, and compare it with evaluate corrosion-fatigue graphs, that as the literature comes moved down of the curve, in relation to the fatigue curve. (author)

  16. Quantitative comparison of the results obtained by the multiple-dose guinea pig maximization test and the non-radioactive murine local lymph-node assay for various biocides.

    Science.gov (United States)

    Yamano, Tetsuo; Shimizu, Mitsuru; Noda, Tsutomu

    2005-07-01

    We compared the results of the multiple-dose guinea pig maximization test (GPMT) and the non-radioactive murine local lymph-node assay (LLNA) for various biocides. Thirteen out of 17 positive biocides in the GPMT gave positive results in the LLNA. In the GPMT, the minimum first induction doses ranged over four orders (0.00005-0.5%), while elicitation-threshold doses, which were evaluated using an optimally sensitized group of animals in the multiple-dose studies, ranged over five orders (0.00006-2.8%). In the LLNA, minimum induction doses ranged over more than three orders (0.01-30%). With respect to 13 biocides that were positive in both the GPMT and the LLNA, results were quantitatively compared. When compared after conversion to corresponding area doses (microg/cm), the minimum doses required to elicit skin reaction in guinea pigs were always lower than that for induction in mice with all biocides. Correlation between minimum induction doses from the GPMT and the LLNA seemed poor (r=0.57), while that between minimum induction doses in the LLNA and elicitation-threshold doses in the GPMT was relatively good (r=0.73). The results suggest the possibility to estimate human elicitation-threshold doses, which are definitely lacking in the process of risk assessment for skin-sensitizers, from the data of the LLNA.

  17. Quantitative comparison of the results obtained by the multiple-dose guinea pig maximization test and the non-radioactive murine local lymph-node assay for various biocides

    International Nuclear Information System (INIS)

    Yamano, Tetsuo; Shimizu, Mitsuru; Noda, Tsutomu

    2005-01-01

    We compared the results of the multiple-dose guinea pig maximization test (GPMT) and the non-radioactive murine local lymph-node assay (LLNA) for various biocides. Thirteen out of 17 positive biocides in the GPMT gave positive results in the LLNA. In the GPMT, the minimum first induction doses ranged over four orders (0.00005-0.5%), while elicitation-threshold doses, which were evaluated using an optimally sensitized group of animals in the multiple-dose studies, ranged over five orders (0.00006-2.8%). In the LLNA, minimum induction doses ranged over more than three orders (0.01-30%). With respect to 13 biocides that were positive in both the GPMT and the LLNA, results were quantitatively compared. When compared after conversion to corresponding area doses (μg/cm), the minimum doses required to elicit skin reaction in guinea pigs were always lower than that for induction in mice with all biocides. Correlation between minimum induction doses from the GPMT and the LLNA seemed poor (r = 0.57), while that between minimum induction doses in the LLNA and elicitation-threshold doses in the GPMT was relatively good (r = 0.73). The results suggest the possibility to estimate human elicitation-threshold doses, which are definitely lacking in the process of risk assessment for skin-sensitizers, from the data of the LLNA

  18. Main results obtained in France in the development of the gaseous diffusion process for uranium isotope separation; Principaux resultats obtenus en France dans les etudes sur la separation des isotopes de l'uranium par diffusion gazeuse

    Energy Technology Data Exchange (ETDEWEB)

    Frejacques, C; Bilous, O; Dixmier, J; Massignon, D; Plurien, P [Commissariat a l' Energie Atomique, Saclay (France). Centre d' Etudes Nucleaires

    1958-07-01

    The main problems which occur in the study of uranium isotope separation by the gaseous diffusion process, concern the development of the porous barrier, the corrosive nature of uranium hexafluoride and also the chemical engineering problems related to process design and the choice of best plant and stage characteristics. Porous barriers may be obtained by chemical attack of non porous media or by agglomeration of very fine powders. Examples of these two types of barriers are given. A whole set of measurement techniques were developed for barrier structure studies, to provide control and guidance of barrier production methods. Uranium hexafluoride reactivity and corrosive properties are the source of many difficult technological problems. A high degree of plant leak tightness must be achieved. This necessity creates a special problem in compressor bearing design. Barrier lifetime is affected by the corrosive properties of the gas, which may lead to a change of barrier structure with time. Barrier hexafluoride permeability measurements have helped to make a systematic study of this point. Finally an example of a plant flowsheet, showing stage types and arrangements and based on a minimisation of enriched product costs is also given as an illustration of some of the chemical engineering problems present. (author) [French] Les principaux problemes qui se sont poses dans l'etude de la separation des isotopes de l'uranium par diffusion gazeuse, sont ceux relatifs a l'obtention de barrieres poreuses, ceux lies a l'utilisation de l'hexafluorure d'uranium, enfin les problemes de genie chimique relatifs au procede et a l'agencement optimum des etages et des cascades entre elles. On peut obtenir des barrieres poreuses soit par attaque de membranes pleines, soit par agglomeration de poudres de petites dimensions. Des exemples de ces deux types de barrieres seront donnes. L'etude des proprietes de texture des barrieres obtenues, necessaire pour orienter les recherches de

  19. Detection of occlusal caries lesions using fluorescence: correlation between histology and obtained results for Diagnodent and spectroscopy; Deteccao de lesoes de carie por fluorescencia: correlacao entre a histologia e os resultados obtidos com o Diagnodent e a espectroscopia

    Energy Technology Data Exchange (ETDEWEB)

    Rocha-Cabral, Renata Maciel

    2006-07-01

    The aims of this study were to develop and test a method to detect caries lesions in vivo and in vitro, using a portable spectrometer (PS); to analyze the performance of PS as well as the commercial device Diagnodent (Dd); correlate them with the gold standard, their transversal section areas and lesions depth and between themselves. 66 occlusal pre-molars sites were examined in vivo with Dd. Sequentially, fluorescence ({lambda}exc {approx} 657 nm) was collected by an optical fiber, conducted to PS and then analyzed as spectra, which were normalized and had calculated the Ratios of their Areas Under the Curves (RAUC) of carious and sound tissues. Experiments were conducted in vitro in the same sites. Gold Standard was obtained by polarized light microscopy. Pearson correlation was used to compare the devices with transversal section area, lesions depth and between themselves. The area under ROC curve, sensitivity, specificity as well as accuracy were calculated and verified with McNemar test. Dd and RAUC showed statistically significant correlation with gold standard (p < 0.01 for Dd and p < 0.05 for RAUC) and between themselves (r = 0,83 in vivo and r = 0,87 in vitro). Although it was significant, the devices showed low correlation with depth of lesions in vivo and in vitro (r = {approx} 0.43). The transversal section area of the lesion had no influence on readings in both devices. Dd showed higher sensitivity (0.76) than PS (0.60) in vivo (p < 0.05), though this fact was not able to improve its performance. In turn, PS showed higher sensitivity (0.88) than Dd (0.79) in vitro, but this difference was not significantly. The other parameters did not show statistically significant differences (p < 0.05) between methods. PS showed positive correlation with Dd, equal correlation with lesions depth and higher ability of detecting the disease in vitro, what suggests that if accompanied with a conic and an angulated probe and a dedicated software, the PS method could be

  20. Blind pre-analysis of the main building complex WWER-440/213 Paks for comparison of analytical and experimental results obtained by explosive testing (task 7a of workplan 95/96)

    International Nuclear Information System (INIS)

    1999-01-01

    Within the research programme on Benchmark studies of seismic analysis of WWER type reactors the blind pre-analysis must be prepared for the main building complex of Paks NPP, based on given excitations derived from explosion tests. The aim of the investigation was to validate different idealization concepts (mathematical models for the idealization of the structures and the soil) as well as investigation procedures (time domain and frequency domain analysis) and finally the software tools by comparing dynamic properties (eigenfrequencies, eigenmodes, modal values) and structural response results (time histories and response spectra). This report contains results of the blind pre-analysis performed by using three dimensional idealization of the main building complex (reactor building, turbine house, galleries) by means of time and frequency domian calculation procedures

  1. Results of flutter test OS6 obtained using the 0.14-scale wing/elevon model (54-0) in the NASA LaRC 16-foot transonic dynamics wind tunnel

    Science.gov (United States)

    Berthold, C. L.

    1977-01-01

    A 0.14-scale dynamically scaled model of the space shuttle orbiter wing was tested in the Langley Research Center 16-Foot Transonic Dynamics Wind Tunnel to determine flutter, buffet, and elevon buzz boundaries. Mach numbers between 0.3 and 1.1 were investigated. Rockwell shuttle model 54-0 was utilized for this investigation. A description of the test procedure, hardware, and results of this test is presented.

  2. Results of flutter test OS7 obtained using the 0.14-scale space shuttle orbiter fin/rudder model number 55-0 in the NASA LaRC 16-foot transonic dynamics wind tunnel

    Science.gov (United States)

    Berthold, C. L.

    1977-01-01

    A 0.14-scale dynamically scaled model of the space shuttle orbiter vertical tail was tested in a 16-foot transonic dynamic wind tunnel to determine flutter, buffet, and rudder buzz boundaries. Mach numbers between .5 and 1.11 were investigated. Rockwell shuttle model 55-0 was used for this investigation. A description of the test procedure, hardware, and results of this test is presented.

  3. Evaluation of the quality of results obtained in institutions participating in interlaboratory experiments and of the reliability characteristics of the analytical methods used on the basis of certification of standard soil samples

    Energy Technology Data Exchange (ETDEWEB)

    Parshin, A.K.; Obol' yaninova, V.G.; Sul' dina, N.P.

    1986-08-20

    Rapid monitoring of the level of pollution of the environment and, especially, of soils necessitates preparation of standard samples (SS) close in properties and material composition to the objects to be analyzed. During 1978-1982 four sets (three types of samples in each) of State Standard Samples of different soils were developed: soddy-podzolic sandy-loamy, typical chernozem, krasnozem, and calcareous sierozem. The certification studies of the SS of the soils were carried out in accordance with the classical scheme of interlab experiment (ILE). More than 100 institutions were involved in the ILE and the total number of independent analytical results was of the order of 10/sup 4/. With such a volume of analytical information at their disposal they were able to find some general characteristics intrinsic to certification studies, to assess the quality of work of the ILE participants with due regard for their specialization, and the reliability characteristics of the analytical methods used.

  4. Summarizing report on results obtained by institutions in Germany and Switzerland applying high-resolution detectors for health physics monitoring; Zusammenfassender Bericht ueber die Inkorporationsmessstellen mit hochaufloesenden Detektoren in Deutschland und der Schweiz

    Energy Technology Data Exchange (ETDEWEB)

    Sahre, P. [Verein fuer Kernverfahrenstechnik und Analytik Rossendorf e.V., Dresden (Germany)

    1997-12-01

    In order to gather as much information as possible about the performance of high-resolution detectors in whole-body and partial-body counters, a questionnaire was distributed to those health physics monitoring institutions in Germany and Switzerland known to apply such instruments. The inquiry also covered institutions in Prague, Budapest, and Seibersdorf which participate in activities of the AKI. The results of the inquiry are given in tabulated form. (orig./CB) [Deutsch] Um moeglichst viele Informationen ueber Ganz- und Teilkoerperzaehler, die mit hochaufloesenden Detektoren arbeiten, zu erfassen, wurde an alle in Deutschland und in der Schweiz arbeitenden Inkorporationsmessstellen ein Formular zur Erfassung von Erfahrungen mit hochaufloesenden Detektoren gesendet. In die Abfrage einbezogen wurden auch Messstellen aus Prag, Budapest und Seibersdorf, die im AKI involviert sind. Die Ergebnisse der Umfrage fuer Ganzkoerperzaehler und fuer Teilkoerperzaehler werden tabellarisch zusammengefasst. (orig./SR)

  5. Alecto - results obtained with homogeneous critical experiments on plutonium 239, uranium 235 and uranium 233; Alecto - resultats des experiences critiques homogenes realisees sur le plutonium 239, l'uranium 235 et l'uranium 233

    Energy Technology Data Exchange (ETDEWEB)

    Bruna, J G; Brunet, J P; Caizegues, R; Clouet d' Orval, Ch; Kremser, J; Tellier, H; Verriere, Ph [Commissariat a l' Energie Atomique, Saclay (France). Centre d' Etudes Nucleaires

    1965-07-01

    In this report are given the results of the homogeneous critical experiments ALECTO, made on plutonium 239, uranium 235 and uranium 233. After a brief description of the equipment, the critical masses for cylinders of diameters varying from 25 to 42 cm, are given and compared with other values (foreign results, criticality guide). With respect to the specific conditions of neutron reflection in the ALECTO experiments the minimal values of critical masses are: Pu239 M{sub c} = 910 {+-} 10 g, U235 M{sub c} = 1180 {+-} 12 g and U233 M{sub c} = 960 {+-} 10 g. Experiments relating to cross sections and constants to be used on these materials are presented. Lastly, kinetic experiments allow to compare pulsed neutron methods to fluctuation methods. [French] On presente dans ce rapport les resultats des experiences critiques homogenes ALECTO, effectuees sur le plutonium 239, l'uranium 235 et l'uranium 233. Apres avoir rappele la description des installations, on donne les masses critiques pour des cylindres de diametres variant entre 25 et 42 cm, qui sont comparees avec d'autres chiffres (resultats etrangers, guide de criticite). Dans les gammes des diametres etudies pour des cuves a fond plat reflechies lateralement, la valeur minimale des masses critiques est la suivante: Pu239 M{sub c} = 910 {+-} 10 g, U235 M{sub c} = 1180 {+-} 12 g et U233 M{sub c} 960 {+-} 10 g. Des experiences portant sur les sections efficaces et les constantes a utiliser sur ces milieux sont ensuite presentees. Enfin des experiences de cinetique permettent une comparaison entre la methode des neutrons pulses et la methode des fluctuations. (auteur)

  6. La influencia de la densidad competitiva en el resultado de los equipos en el fútbol de alto nivel. (The influence of a congested football calendar on the results obtained by teams in professional soccer.

    Directory of Open Access Journals (Sweden)

    Joaquín Lago Ballesteros

    2009-01-01

    Full Text Available Resumen Existe una considerable variación en el número de partidos disputados por los equipos de fútbol durante una temporada. Los mejores equipos juegan varios partidos a la semana tanto en las competiciones domesticas como en la Liga de Campeones. Se ha especulado que un período cargado de partidos puede limitar el rendimiento de los conjuntos. En este trabajo se estudia el efecto que tiene para un equipo disputar un partido de la Liga de Campeones sobre el resultado alcanzado en el encuentro de la Liga Española en el fin de semana anterior. La muestra consiste en 374 partidos de la Liga Española jugados por los equipos que se encontraban simultáneamente disputando la Liga de Campeones entre las temporadas 2003-2004 y 2006- 2007. Los resultados alcanzados mediante un modelo logit multinomial permiten demostrar que disputar un partido de la Liga de Campeones no reduce la probabilidad de ganar en el partido de la Liga Española. Además se ha verificado que la probabilidad de ganar en el partido del fin de semana de la Liga Española es mayor cuando el partido de la Liga de Campeones a disputar pertenece a la fase de liguilla respecto a si se corresponde con el formato de eliminación directa.Palabras clave: fútbol; liga española; liga de campeones; logit multinomial; densidad competitive. Abstract There is a considerable variation in the number of matches played per season by clubs in the Spanish Soccer. The successful top clubs play several matches a week in domestic leagues as well as in the UEFA Champions League. It has been speculated that a period full of matches can lead to player fatigue which may result in underperformance. Using data from 374 matches of the Spanish Soccer League played from the 2003-04 to the 2006-07 seasons and according to the estimation based on logit multinomial this study shows that Spanish Champions League teams did not perform below their normal standard at the weekend when they played a Champions

  7. Analysis of personnel monitoring results of external radiation doses received by occupationally exposed workers obtained using CaSO4: Dy TLD personnel monitoring badges at RAPS (2000-2004)

    International Nuclear Information System (INIS)

    Chourasiya, G.; Kher, R.K.; Rao, B.S.; Pradhan, S.M.

    2006-01-01

    Personnel monitoring is a key step in radiation protection programme. It helps in keeping a check on radiation hazards and safety aspects of the operating unit. Moreover, analysis of the temporal trends in exposure histories of the individuals/groups play an important role in assessing the need of improved standards of protection and the impact of implementation of such measures. The paper presents the analysis of annual effective dose and collective dose to the radiation workers, which are indicators of individual risk and the impact of the practice. The present study also gives the analysis of the effective dose, cumulative dose and various dose distribution ratios (SR E and NR E ) for the block of 5 years (2000-2004) of RAPS 1 and 2 the oldest PHWR in the country and RAPS 3 and 4 the latest in the series incorporating many improvements in design and operation. It is seen that occupational exposures at NPPs have been showing a steadily decreasing trend, which is a result of a number of design improvements, operation and protection measures. However, to achieve world standards, we have to go a long way by further carrying out identification of areas of improvement, good operating practices along with the desired modifications in design. (author)

  8. Obtaining zircaloy powder through hydriding

    International Nuclear Information System (INIS)

    Dupim, Ivaldete da Silva; Moreira, Joao M.L.

    2009-01-01

    Zirconium alloys are good options for the metal matrix in dispersion fuels for power reactors due to their low thermal neutron absorption cross-section, good corrosion resistance, good mechanical strength and high thermal conductivity. A necessary step for obtaining such fuels is producing Zr alloy powder for the metal matrix composite material. This article presents results from the Zircaloy-4 hydrogenation tests with the purpose to embrittle the alloy as a first step for comminuting. Several hydrogenation tests were performed and studied through thermogravimetric analysis. They included H 2 pressures of 25 and 50 kPa and temperatures ranging between from 20 to 670 deg C. X-ray diffraction analysis showed in the hydrogenated samples the predominant presence of ZrH 2 and some ZrO 2 . Some kinetics parameters for the Zircaloy-4 hydrogenation reaction were obtained: the time required to reach the equilibrium state at the dwell temperature was about 100 minutes; the hydrogenation rate during the heating process from 20 to 670 deg C was about 21 mg/h, and at constant temperature of 670 deg C, the hydride rate was about 1.15 mg/h. The hydrogenation rate is largest during the heating process and most of it occurs during this period. After hydrogenated, the samples could easily be comminuted indicating that this is a possible technology to obtain Zircaloy powder. The results show that only few minutes of hydrogenation are necessary to reach the hydride levels required for comminuting the Zircaloy. The final hydride stoichiometry was between 2.7 and 2.8 H for each Zr atom in the sample (author)

  9. Evaluation of real-time data obtained from gravimetric preparation of antineoplastic agents shows medication errors with possible critical therapeutic impact: Results of a large-scale, multicentre, multinational, retrospective study.

    Science.gov (United States)

    Terkola, R; Czejka, M; Bérubé, J

    2017-08-01

    Medication errors are a significant cause of morbidity and mortality especially with antineoplastic drugs, owing to their narrow therapeutic index. Gravimetric workflow software systems have the potential to reduce volumetric errors during intravenous antineoplastic drug preparation which may occur when verification is reliant on visual inspection. Our aim was to detect medication errors with possible critical therapeutic impact as determined by the rate of prevented medication errors in chemotherapy compounding after implementation of gravimetric measurement. A large-scale, retrospective analysis of data was carried out, related to medication errors identified during preparation of antineoplastic drugs in 10 pharmacy services ("centres") in five European countries following the introduction of an intravenous workflow software gravimetric system. Errors were defined as errors in dose volumes outside tolerance levels, identified during weighing stages of preparation of chemotherapy solutions which would not otherwise have been detected by conventional visual inspection. The gravimetric system detected that 7.89% of the 759 060 doses of antineoplastic drugs prepared at participating centres between July 2011 and October 2015 had error levels outside the accepted tolerance range set by individual centres, and prevented these doses from reaching patients. The proportion of antineoplastic preparations with deviations >10% ranged from 0.49% to 5.04% across sites, with a mean of 2.25%. The proportion of preparations with deviations >20% ranged from 0.21% to 1.27% across sites, with a mean of 0.71%. There was considerable variation in error levels for different antineoplastic agents. Introduction of a gravimetric preparation system for antineoplastic agents detected and prevented dosing errors which would not have been recognized with traditional methods and could have resulted in toxicity or suboptimal therapeutic outcomes for patients undergoing anticancer treatment.

  10. Results in energy saving obtained with the application of speed variator in fossil power stations; Resultados de ahorro de energia obtenidos con la aplicacion de variadores de velocidad en centrales termoelectricas

    Energy Technology Data Exchange (ETDEWEB)

    Merlos Rueda, Rosa Maria [Programa de Ahorro de Energia del Sector Electrico (PAESE), Mexico, D. F. (Mexico)

    1999-07-01

    The project of installation of speed variator in fossil power stations (CT's) of Comision Federal de Electricidad (CFE), as an energy saving measure, is a pilot project that began with the support of the Subdivision de Generacion, and promoted by the Energy Saving Program of the Electric Sector (PAESE), with the putting in operation of an equipment in the condensate pump of the Punta Prieta II C. T. U3. The energy saving observed was substantial, fluctuating between the 19.4% at high loads (at 90% load) and the 71.1% at low loads (at 40% load) of the generating unit. With these results, it was decided to extend the scope of the project with the installation of 6 more equipment for equal number of fossil power stations, located in 4 of the 5 Regions of Generation. The fossil power stations, selected for this stage of the project were: C. T. Felipe Carrillo Puerto U1, C.T. Lerma U4, C.T. Salamanca U1, C.T. Monterrey U6, C.T. Francisco Villa U3 and the C.T. Punta Prieta II-U1. The equipment was in operation during the first quarter of 1998, and the first results indicate an energy savings average per equipment, between 39% and 52%. The recovery of the investment fluctuates between the 48.4% and the 87.6% in less than two years of operation, with which a maximum period of recovery of 3 years is expected. The estimated potential of energy saving, considering the application of these devices in condensate pumps, feedwater pumps (where no speed variator is installed) forced draft fans, induced draft fans and gas recirculation fans, as well as circulation water pumps, of the existing Generating Power stations, ascends to an annual total of 830,000, which represents an approximate 9.4% of the National consumption of self services. [Spanish] El proyecto de instalacion de variadores de velocidad en Centrales Termoelectricas (CT's) de la Comision Federal de Electricidad (CFE), como medida de ahorro de energia, es un proyecto piloto que se inicio con el apoyo de la

  11. First results obtained by the Cluster STAFF experiment

    Czech Academy of Sciences Publication Activity Database

    Cornilleau-Wehrlin, N.; Chanteur, G.; Perraut, S.; Rezeau, L.; Robert, P.; Roux, A.; Villedary de, C.; Canu, P.; Maksimovic, M.; Conchy de, Y.; Hubert, D.; Lacombe, C.; Lefeuvre, F.; Parrot, M.; Pincon, J. L.; Decrau, P. M. E.; Harvey, C. C.; Louarn, Ph.; Santolík, Ondřej; Alleyne, H. St. C.; Roth, M.; Chust, T.; Contel Le, O.

    2003-01-01

    Roč. 21, - (2003), s. 437-456 ISSN 0992-7689 R&D Projects: GA ČR GA202/03/0832; GA MŠk ME 650 Institutional research plan: CEZ:AV0Z3042911 Keywords : magnetospheric physics * space plasma physics Subject RIV: BL - Plasma and Gas Discharge Physics Impact factor: 1.031, year: 2003

  12. Calibration results obtained with Liulin-4 type dosimeters

    Czech Academy of Sciences Publication Activity Database

    Dacheva, T.; Tomova, B.; Matviichuka, Y.; Dimitrova, P.; Lemaireb, J.; Gregoirec, G.; Cyamukunguc, M.; Schmitzc, H.; Fujitakad, K.; Uchihorid, Y.; Kitamurad, H.; Reitze, G.; Beaujeanf, R.; Petrovg, V.; Shurshakovg, V.; Benghing, V.; Spurný, František

    2002-01-01

    Roč. 30, č. 4 (2002), s. 917-925 ISSN 0273-1177 Institutional research plan: CEZ:AV0Z1048901 Keywords : CERN high-energy reference field * detector * dosimeter Subject RIV: BG - Nuclear, Atomic and Molecular Physics, Colliders Impact factor: 0.448, year: 2002

  13. The impact of comorbid post-traumatic stress disorder in patients with major depressive disorder on clinical features, pharmacological treatment strategies, and treatment outcomes - Results from a cross-sectional European multicenter study.

    Science.gov (United States)

    Dold, Markus; Bartova, Lucie; Kautzky, Alexander; Souery, Daniel; Mendlewicz, Julien; Serretti, Alessandro; Porcelli, Stefano; Zohar, Joseph; Montgomery, Stuart; Kasper, Siegfried

    2017-07-01

    This international, multicenter, cross-sectional study comprising 1346 adult in- and outpatients with major depressive disorder (MDD) investigated the association between MDD as primary diagnosis and comorbid post-traumatic stress disorder (PTSD). In a cross-sectional data collection process, the presence of comorbid PTSD was determined by the Mini International Neuropsychiatric Interview (MINI) and the patients' socio-demographic, clinical, psychopharmacological, and response information were obtained. Clinical features between MDD with and without concurrent PTSD were compared using descriptive statistics, analyses of covariance (ANCOVA), and binary logistic regression analyses. 1.49% of the MDD patients suffered from comorbid PTSD. Significantly more MDD + comorbid PTSD patients exhibited atypical features, comorbid anxiety disorders (any comorbid anxiety disorder, panic disorder, agoraphobia, and social phobia), comorbid bulimia nervosa, current suicide risk, and augmentation treatment with low-dose antipsychotic drugs. In the binary logistic regression analyses, the presence of atypical features (odds ratio (OR) = 4.49, 95%CI:1.01-20.12; p≤.05), any comorbid anxiety disorder (OR = 3.89, 95%CI:1.60-9.44; p = .003), comorbid panic disorder (OR = 6.45, 95%CI:2.52-16.51; p = .001), comorbid agoraphobia (OR = 6.51, 95%CI:2.54-16.68; p≤.001), comorbid social phobia (OR = 6.16, 95%CI:1.71-22.17; p≤.001), comorbid bulimia nervosa (OR = 10.39, 95%CI:1.21-88.64; p = .03), current suicide risk (OR = 3.58, 95%CI:1.30-9.91; p = .01), and augmentation with low-potency antipsychotics (OR = 6.66, 95%CI:2.50-17.77; pdisorders, and (3.) the increased suicide risk due to concurrent PTSD. Copyright © 2017 Elsevier B.V. and ECNP. All rights reserved.

  14. THE COMPATIBILITY STUDENT CHOICE OF UNIVERSITY MAJORING; A PRELIMINARY STUDIES

    Directory of Open Access Journals (Sweden)

    Daharnis Daharnis

    2016-06-01

    Full Text Available The continuous improvements in order to optimize the basic education to higher education are still running. Based on that purpose, there are many factors to supporting the students' learning activities success; one of the factors is suitability with majors in university. The purpose of this study is to reveal the condition of the compatibility of students majoring with their interest, then to describe the information when the student choose their majoring. Samples in this study were 122 peoples, taken by random sampling from the Padang State University. Data obtained by distributing questionnaires. The results showed that there are students that their major do not match with their interest (22.13%, only 3.28% of students who feel compatible with their major. This result should be a major concern, particularly for counselor in schools for design counseling services to solve these problems. The result of this study used as a grand tour or a preliminary study for further research.

  15. The prevalence and illness characteristics of DSM-5-defined "mixed feature specifier" in adults with major depressive disorder and bipolar disorder: Results from the International Mood Disorders Collaborative Project.

    Science.gov (United States)

    McIntyre, Roger S; Soczynska, Joanna K; Cha, Danielle S; Woldeyohannes, Hanna O; Dale, Roman S; Alsuwaidan, Mohammad T; Gallaugher, Laura Ashley; Mansur, Rodrigo B; Muzina, David J; Carvalho, Andre; Kennedy, Sidney H

    2015-02-01

    A substantial proportion of individuals with mood disorders present with sub-syndromal hypo/manic features. The objective of this analysis was to evaluate the prevalence and illness characteristics of the Diagnostic and Statistical Manual Version-5 (DSM-5) - defined mixed features specifier (MFS) in adults with major depressive disorder (MDD) and bipolar disorder (BD). Data from participants who met criteria for a current mood episode as part of MDD (n=506) or BD (BD-I: n=216, BD-II: n=130) were included in this post-hoc analysis. All participants were enrolled in the International Mood Disorders Collaborative Project (IMDCP): a collaborative research platform at the Mood Disorders Psychopharmacology Unit, University of Toronto and the Cleveland Clinic, Cleveland, Ohio. Mixed features specifier was operationalized as a score ≥ 1 on 3 or more select items on the Young Mania Rating Scale (YMRS) or ≥ 1 on 3 select items of the Montgomery Åsberg Depression Rating Scale (MADRS) or Hamilton Depression Rating Scale (HAMD-17) during an index major depressive episode (MDE) or hypo/manic episode, respectively. A total of 26.0% (n=149), 34.0% (n=65), and 33.8% (n=49) of individuals met criteria for MFS during an index MDE as part of MDD, BD-I and BD-II, respectively. Mixed features specifier during a hypo/manic episode was identified in 20.4% (n=52) and 5.1% (n=8) in BD-I and BD-II participants, respectively. Individuals with MDE-MFS as part of BD or MDD exhibited a more severe depressive phenotype (p=0.0002 and pdefined MFS is common during an MDE as part of MDD and BD. The presence of MFS identifies a subgroup of individuals with greater illness complexity and possibly a higher rate of cardiovascular comorbidity. The results herein underscore the common occurrence of MFS in adults with either BD or MDD. Moreover, the results of our analysis indicate that adults with mood disorders and MFS have distinct clinical characteristics and comorbidity patterns. Copyright

  16. Participation in a Year-Long CURE Embedded into Major Core Genetics and Cellular and Molecular Biology Laboratory Courses Results in Gains in Foundational Biological Concepts and Experimental Design Skills by Novice Undergraduate Researchers†

    Science.gov (United States)

    Peteroy-Kelly, Marcy A.; Marcello, Matthew R.; Crispo, Erika; Buraei, Zafir; Strahs, Daniel; Isaacson, Marisa; Jaworski, Leslie; Lopatto, David; Zuzga, David

    2017-01-01

    This two-year study describes the assessment of student learning gains arising from participation in a year-long curriculum consisting of a classroom undergraduate research experience (CURE) embedded into second-year, major core Genetics and Cellular and Molecular Biology (CMB) laboratory courses. For the first course in our CURE, students used micro-array or RNAseq analyses to identify genes important for environmental stress responses by Saccharomyces cerevisiae. The students were tasked with creating overexpressing mutants of their genes and designing their own original experiments to investigate the functions of those genes using the overexpression and null mutants in the second CURE course. In order to evaluate student learning gains, we employed three validated concept inventories in a pretest/posttest format and compared gains on the posttest versus the pretest with student laboratory final grades. Our results demonstrated that there was a significant correlation between students earning lower grades in the Genetics laboratory for both years of this study and gains on the Genetics Concept Assessment (GCA). We also demonstrated a correlation between students earning lower grades in the Genetics laboratory and gains on the Introductory Molecular and Cell Biology Assessment (IMCA) for year 1 of the study. Students furthermore demonstrated significant gains in identifying the variable properties of experimental subjects when assessed using the Rubric for Experimental (RED) design tool. Results from the administration of the CURE survey support these findings. Our results suggest that a year-long CURE enables lower performing students to experience greater gains in their foundational skills for success in the STEM disciplines. PMID:28904646

  17. Biodegradable Polyelectrolyte Obtained by Radiation Polymerization

    International Nuclear Information System (INIS)

    Craciun, G.; Martin, D.; Manaila, E.; Nemtanu, M.; Brasoveanu, M.; Ighigeanu, D.

    2009-01-01

    Poly electrolytes are water-soluble polymers carrying ionic charge along the polymer chain. Depending upon the charge, these polymers are anionic or cationic. The inherent solid - liquid separating efficiency makes these poly electrolytes a unique class of polymers which find extensive application in potable water, industrial raw and process water, municipal sewage treatment, mineral processing and metallurgy, oil drilling and recovery, etc. Also, due to their ability to produce advanced induced coagulation, a considerable amount of bacteria and viruses are precipitated together with the suspended solids. Especially the acrylamide polymers are very efficacious for water treatment but acrylamide is a toxic monomer and therefore their use are governed by international standards that provide the residual acrylamide monomer content (RAMC) in them be less than 0.05%. Under these circumstances our attention was focused on the following research steps that are presented in this paper: 1) Preparation of a special class of poly electrolytes, named Pn, with very low RAMC values, based on electron beam (EB), microwave (MW) and EB + MW induced co-polymerization of aqueous solutions containing appropriate mixtures of acrylamide (AMD) and acrylic acid (AA) monomers (AMD - AA co-polymers). The Pn were obtained by radiation technology with very small RAMC (under 0.01%) as well as in a wide range of molecular weights and charge densities. Very low AMD monomer content of Pn is due to the major advantages of radiation induced polymerization in aqueous solution containing monomers. Due to water presence in the EB irradiated system, irradiated water radicals facilitate the polymerization process and increase rate and level of monomers conversion in co-polymers. Also, once again, by the presence of water, which absorbs MW energy very strongly, the MW polymerization reaction rate is much enhanced resulting in a reaction time about 50-100 times lowers than by conventional heating. Also

  18. Adjuvant occupational therapy improves long-term depression recovery and return-to-work in good health in sick-listed employees with major depression: results of a randomised controlled trial

    NARCIS (Netherlands)

    Hees, Hiske L.; de Vries, Gabe; Koeter, Maarten W. J.; Schene, Aart H.

    2013-01-01

    To evaluate whether adjuvant occupational therapy (OT) can improve the effectiveness of treatment-as-usual (TAU) in sick-listed employees with major depression. In total, 117 employees sick-listed for a median duration of 4.8 months (IQR=2.6 to 10.1 months) because of major depression were

  19. Rosa damascena oil improves SSRI-induced sexual dysfunction in male patients suffering from major depressive disorders: results from a double-blind, randomized, and placebo-controlled clinical trial

    Directory of Open Access Journals (Sweden)

    Farnia V

    2015-03-01

    Full Text Available Vahid Farnia,1 Mehdi Shirzadifar,2 Jalal Shakeri,1 Mansour Rezaei,3 Hafez Bajoghli,4,5 Edith Holsboer-Trachsler,6 Serge Brand6,7 1Substance Abuse Prevention Research Center, Psychiatry Department, Kermanshah University of Medical Sciences, Kermanshah, Iran; 2Student Research Center, Psychiatry Department, Kermanshah University of Medical Sciences, Kermanshah, Iran; 3Department of Statistics and Epidemiology, Kermanshah University of Medical Sciences, Kermanshah, Iran; 4Iranian National Center for Addiction Studies, Iranian Institute for Reduction of High-Risk Behaviors, Tehran University of Medical Sciences, Tehran, Iran; 5ASEAN Institute for Health Development, Mahidol University, Nakhon Pathom, Thailand; 6Psychiatric Clinics of the Center for Affective, Stress and Sleep Disorders, Psychiatric Hospital of the University of Basel, Basel, Switzerland; 7Sport Science Section, Department of Sport, Exercise and Health, University of Basel, Basel, Switzerland Background: A substantial disadvantage of psychopharmacological treatment of major depressive disorder (MDD with selective serotonin-reuptake inhibitors (SSRIs is the impact on sexual dysfunction. The aim of the present study was to investigate whether the oil of Rosa damascena can have a positive influence on SSRI-induced sexual dysfunction (SSRI-I SD of male patients who are suffering from MDD and are being treated with SSRIs.Method: In a double-blind, randomized, and placebo-controlled clinical trial, a total of 60 male patients treated with an SSRI and suffering from MDD (mean age =32 years and SSRI-I SD were randomly assigned to take either verum (R. damascena oil or a placebo. Patients completed self-ratings of depression and sexual function at baseline, at 4 weeks later, and at the end of the study, 8 weeks after it started.Results: Over time, sexual dysfunction improved more in the verum group than in the control group. Improvements were observed in the verum group from week 4 to week

  20. Pitfalls and major issues in the histologic diagnosis of peripheral T-cell lymphomas: results of the central review of 573 cases from the T-Cell Project, an international, cooperative study.

    Science.gov (United States)

    Bellei, Monica; Sabattini, Elena; Pesce, Emanuela Anna; Ko, Young-Hyeh; Kim, Won Seog; Cabrera, Maria Elena; Martinez, Virginia; Dlouhy, Ivan; Paes, Roberto Pinto; Barrese, Tomas; Vassallo, Josè; Tarantino, Vittoria; Vose, Julie; Weisenburger, Dennis; Rüdiger, Thomas; Federico, Massimo; Pileri, Stefano

    2017-12-01

    Peripheral T-cell lymphomas (PTCLs) comprise a heterogeneous group of neoplasms that are derived from post-thymic lymphoid cells at different stages of differentiation with different morphological patterns, phenotypes and clinical presentations. PTCLs are highly diverse, reflecting the diverse cells from which they can originate and are currently sub-classified using World Health Organization (WHO) 2008 criteria. In 2006 the International T-Cell Lymphoma Project launched the T-Cell Project, building on the retrospective study previously carried on by the network, with the aim to prospectively collect accurate data to improve knowledge on this group of lymphomas. Based on previously published reports from International Study Groups it emerged that rendering a correct classification of PTCLs is quite difficult because the relatively low prevalence of these diseases results in a lack of confidence by most pathologists. This is the reason why the T-Cell Project requested the availability of diagnostic material from the initial biopsy of each patient registered in the study in order to have the initial diagnosis centrally reviewed by expert hematopathologists. In the present report the results of the review process performed on 573 cases are presented. Overall, an incorrect diagnosis was centrally recorded in 13.1% cases, including 8.5% cases centrally reclassified with a subtype eligible for the project and 4.6% cases misclassified and found to be disorders other than T-cell lymphomas; 2.1% cases were centrally classified as T-Cell disorders not included in the study population. Thus, the T-Cell Project confirmed the difficulties in providing an accurate classification when a diagnosis of PTCLs is suspected, singled out the major pitfalls that can bias a correct histologic categorization and confirmed that a centralized expert review with the application of adequate diagnostic algorithms is mandatory when dealing with these tumours. Copyright © 2016 John Wiley & Sons

  1. Truncated States Obtained by Iteration

    International Nuclear Information System (INIS)

    Cardoso, W. B.; Almeida, N. G. de

    2008-01-01

    We introduce the concept of truncated states obtained via iterative processes (TSI) and study its statistical features, making an analogy with dynamical systems theory (DST). As a specific example, we have studied TSI for the doubling and the logistic functions, which are standard functions in studying chaos. TSI for both the doubling and logistic functions exhibit certain similar patterns when their statistical features are compared from the point of view of DST

  2. Major results on the development of high density U-Mo fuel and pin-type fuel elements executed under the Russian RERTR program and in cooperation with ANL (USA)

    International Nuclear Information System (INIS)

    Vatulin, A.; Morozov, A.; Stetsky, Y.; Suprun, V.; Dobrikova, I.; Trifonov, Y.; Mishunin, V.; Sorokin, V.

    2003-01-01

    VNIINM is active participant of 'Russian program on Reduced Enrichment for Research and Test Reactors'. Institute Works in two main directions: 1) development of new high-density fuels (HDF) and 2) development of new design of fuel elements with LEU. The development of the new type fuel element is carried out both for existing reactors, and for developing new advanced reactors. The 'TVEL' concern is coordinator of works of this program. The majority enterprises of branch (NIIAR, PIYaF, RRC KI, NZChK) take part in this work. Since 2000 these works are being conducted in cooperation with Argonne National Laboratory (USA) within the RERTR program under VNIINM with ANL contract. At the present, a large set of pre-pile investigations has been completed. All necessary fabrication procedures have been developed for utilization of U-Mo dispersion fuel in Russian-designed research reactors. For irradiation tests the pin-type mini-fuel elements with HDF dispersion fuel with LEU and the uranium density equaled to 4,0 and 6,0 g/cm 3 (up to 40 vol.%) have been manufactured. Their irradiation began in August 2003 in the MIR reactor (NIIAR, Dimitrovgrad). A large set of works for preparation of lifetime tests (WWR-M reactor in Gatchina) of two full-scale fuel assemblies with new pin-type fuel elements on basis LEU UO 2 -Al and UMo-Al fuels has been completed. The in-pile tests of fuel assemblies began in September 2003. The summary of important results of performed works and their near-term future are presented in paper. (author)

  3. Plasticity characteristic obtained by indentation

    International Nuclear Information System (INIS)

    Milman, Yu V

    2008-01-01

    A dimensionless parameter δ H = ε p /ε t (where ε p and ε t are the average values of plastic and total deformation of material on the contact area indenter-specimen) may be used as the plasticity characteristic of materials, which made it possible to characterize the plasticity of materials that are brittle in standard mechanical tests. δ H may be calculated from the values of microhardness HM, Young's modulus E and Poisson's ratio ν. In instrumented indentation the plasticity characteristic δ A = A p /A t (A p and A t are the work of plastic and total deformation during indentation) may be calculated. δ A ∼ δ H for materials with δ H > 0.5, i.e. for all metals and the majority of ceramic materials. In this case, the theoretical equation δ A ∼ δ H = 1-10.2 · (1 - ν - 2ν 2 )(HM/E) is satisfied in experiments with the Berkovich indenter. The influence of the temperature and structural parameters (dislocation density and grain size including nanostructured materials) on δ H is discussed

  4. Major Sport Venues

    Data.gov (United States)

    Department of Homeland Security — The Major Public Venues dataset is composed of facilities that host events for the National Association for Stock Car Auto Racing, Indy Racing League, Major League...

  5. Major Depression Among Adults

    Science.gov (United States)

    ... Depressive Episode Among Adolescents Data Sources Share Major Depression Definitions Major depression is one of the most ... Bethesda, MD 20892-9663 Follow Us Facebook Twitter YouTube Google Plus NIMH Newsletter NIMH RSS Feed NIMH ...

  6. Psychosocial implications of Thalassemia Major.

    Science.gov (United States)

    Aydinok, Yesim; Erermis, Serpil; Bukusoglu, Nagihan; Yilmaz, Deniz; Solak, Ufuk

    2005-02-01

    Many causes including the chronicity of disease, burden of treatment modalities, morbidities, and the expectation of early death resulting from the disease complications, may lead to psychosocial burden in Thalassemia Major (TM) patients. A total of 38 patients with TM and their mothers were recruited to evaluate the psychosocial burden as well as to disclose whether the psychological status of the patients contribute to the compliance with the therapy or to the contrary. Demographic and disease variables were obtained. Child Behavior Check-list (CBCL) was completed by the mothers of the patients. A detailed psychiatric interview based on the 4th edition of the Diagnostic and Statistical Manual diagnostic criteria was performed for each patient. Symptom Distress Checklist 90 (SCL-90) scale was given to all mothers for evaluating their psychopathology. Although CBCL scores remained between the normal ranges, desferrioxamine mesylate (DFO)-compliant patients and the patients with lower ferritin values had significantly higher scores. A total of 24% of the patients had a psychiatric diagnosis including major depression, anxiety disorder, tic disorder, and enuresis nocturnal. The psychiatric diagnosis was significantly higher in the patients who were compliant with desferrioxamine compared with the non-compliant group (P = 0.007). The SCL-90 scores indicated that the mothers who had a child with good adherence to DFO had higher scale scores than the mothers with a poor adherent child. The increase risk of psychosocial and behavioral problems in thalassemics and their parents indicated the importance of a lifelong psychosocial support for the prevention of mental health issues. The patients and their parents, who were more conscious of the illness, were more worried but more compliant with the therapy and need stronger psychiatric support.

  7. Comparative Effect of Collaborative Care, Pain Medication, and Duloxetine in the Treatment of Major Depressive Disorder and Comorbid (SubChronic Pain: Results of an Exploratory Randomized, Placebo-Controlled, Multicenter Trial (CC:PAINDIP

    Directory of Open Access Journals (Sweden)

    Eric W. de Heer

    2018-04-01

    Full Text Available ObjectiveEvidence exists for the efficacy of collaborative care (CC for major depressive disorder (MDD, for the efficacy of the consequent use of pain medication against pain, and for the efficacy of duloxetine against both MDD and neuropathic pain. Their relative effectiveness in comorbid MDD and pain has never been established so far. This study explores the effectiveness of CC with pain medication and duloxetine, and CC with pain medication and placebo, compared with duloxetine alone, on depressive and pain symptoms. This study was prematurely terminated because of massive reorganizations and reimbursement changes in mental health care in the Netherlands during the study period and is therefore of exploratory nature.MethodsThree-armed, randomized, multicenter, placebo-controlled trial at three specialized mental health outpatient clinics with patients who screened positive for MDD. Interventions lasted 12 weeks. Pain medication was administered according to an algorithm that avoids opiate prescription as much as possible, where paracetamol, COX inhibitors, and pregabalin are offered as steps before opiates are considered. Patients who did not show up for three or more sessions were registered as non-compliant. Explorative, intention-to-treat and per protocol, multilevel regression analyses were performed. The trial is listed in the trial registration (http://www.trialregister.nl/trialreg/admin/rctview.asp?TC=1089; NTR number: NTR1089.ResultsSixty patients completed the study. Patients in all treatment groups reported significantly less depressive and pain symptoms after 12 weeks. CC with placebo condition showed the fastest decrease in depressive symptoms compared with the duloxetine alone group (b = −0.78; p = 0.01. Non-compliant patients (n = 31 did not improve over the 12-week period, in contrast to compliant patients (n = 29. Pain outcomes did not differ between the three groups.ConclusionIn MDD and pain, patient

  8. Obtaining of polycrystalline silicon for semiconductor industry

    International Nuclear Information System (INIS)

    Mukashev, F.; Nauryzbaev, M.; Kolesnikov, B.; Ivanov, Y.

    1996-01-01

    The purpose of the project is to create pilot equipment and optimize the process of obtaining polycrystalline silicon on semi-industrial level. In the past several decades, the historical experience in the developing countries has shown that one of the most promising ways to improve the economy,of a country is to establish semiconductor industry. First of all, the results can help increase defense, national security and create industrial production. The silane method, which has been traditionally' used for obtaining technical and polycrystalline silicon, is to obtain and then to pyrolyzed mono-and poly silanes. Although the traditional methods of obtaining silicon hydrides have specific advantages, such as utilizing by-products, they also have clear shortcomings, i.e. either low output of the ultimate product ( through hydrolysis of Mg 2 Si) or high contents of by-products in it or high contents of dissolving vapors (through decomposing Mg 2 Si in non-water solutions)

  9. Process for obtaining cobalt and lanthanum nickelate

    International Nuclear Information System (INIS)

    Tapcov, V.; Samusi, N.; Gulea, A.; Horosun, I.; Stasiuc, V.; Petrenco, P.

    1999-01-01

    The invention relates to the process for obtaining polycrystalline ceramics of cobalt and lanthanum nickelate with the perovskite structure from coordinative hetero metallic compounds. The obtained products can be utilized in the industry in the capacity of catalysts. Summary of the invention consists in obtaining polycrystalline ceramics LaCoO 3 and LaNiO 3 with the perovskite structure by pyrolysis of the parent compounds, namely, the coordinative hetero metallic compounds of the lanthanum cobalt or lanthanum nickel. The pyrolysis of the parent compound runs during one hour at 800 C. The technical result of the invention consists in lowering the temperature of the parent compound pyrolysis containing the precise ratio of metals necessary for ceramics obtaining

  10. Experiments for obtaining field influence mass particles.

    CERN Document Server

    Yahalomi, E

    2010-01-01

    Analyzing time dilation experiments the existence of a universal field interacting with moving mass particles is obtained. It is found that mass particle changes its properties depend on its velocity relative to this universal scalar field and not on its velocity relative to the laboratory. High energy proton momentum, energy and mass were calculated obtaining new results. Experiments in high energy accelerators are suggested as additional proofs for the existence of this universal field. This universal field may explain some results of other high energy experiments.

  11. Comparative effect of collaborative care, pain medication, and duloxetine in the treatment of major depressive disorder and comorbid (Sub)chronic pain: Results of an exploratory randomized, placebo-controlled, multicenter trial (CC:PAINDIP)

    NARCIS (Netherlands)

    de Heer, Eric W.; Dekker, Jack; Beekman, Aartjan T.F.; van Marwijk, Harm W.J.; Holwerda, Tjalling J.; Bet, Pierre M.; Roth, Joost; Timmerman, Lotte; van der Feltz-Cornelis, Christina M.

    2018-01-01

    Objective: Evidence exists for the efficacy of collaborative care (CC) for major depressive disorder (MDD), for the efficacy of the consequent use of pain medication against pain, and for the efficacy of duloxetine against both MDD and neuropathic pain. Their relative effectiveness in comorbid MDD

  12. Drugs obtained by biotechnology processing

    Directory of Open Access Journals (Sweden)

    Hugo Almeida

    2011-06-01

    Full Text Available In recent years, the number of drugs of biotechnological origin available for many different diseases has increased exponentially, including different types of cancer, diabetes mellitus, infectious diseases (e.g. AIDS Virus / HIV as well as cardiovascular, neurological, respiratory, and autoimmune diseases, among others. The pharmaceutical industry has used different technologies to obtain new and promising active ingredients, as exemplified by the fermentation technique, recombinant DNA technique and the hybridoma technique. The expiry of the patents of the first drugs of biotechnological origin and the consequent emergence of biosimilar products, have posed various questions to health authorities worldwide regarding the definition, framework, and requirements for authorization to market such products.Nos últimos anos, tem aumentado exponencialmente o número de fármacos de origem biotecnológica ao dispor das mais diversas patologias, entre elas destacam-se, os diferentes tipos de cancêr, as doenças infecciosas (ex. vírus AIDS/HIV, as doenças autoimunes, as doenças cardiovasculares, a Diabetes Mellitus, as doenças neurológicas, as doenças respiratórias, entre outras. A indústria farmacêutica tem recorrido a diferentes tecnologias para a obtenção de novos e promissores princípios ativos, como são exemplo a fermentação, a técnica de DNA Recombinante, a técnica de hidridoma, entre outras. A queda das patentes dos primeiros fármacos de origem biotecnológica e o consequente aparecimento dos produtos biossimilares têm colocado diferentes questões às autoridades de saúde mundiais, sobre a definição, enquadramento e exigências para a autorização de entrada no mercado deste tipo de produtos.

  13. Hydrodynamic analysis of the artificial recharge of aquifers during the planning stage. Results obtained in the Quaternary aquifer in the Valley of the Guadalquivir (Spain); Analisis hidrodinamico de la recarga artificial de acuiferos durante la etapa de planificacion. Resultados obtenidos en el acuifero cuaternario del valle del Guadalquivir (Espana)

    Energy Technology Data Exchange (ETDEWEB)

    Murillo, J. M.

    2014-10-01

    This paper shows a study on the viability of an artificial recharge in the flood-plain aquifer of the Guadalquivir River (Andalucia, Spain). The method used to the evaluation of the artificial recharge project is as follows: A simple model (one cell). The code has been made on the use of an EXCEL spreadsheet. A distributed parameters-flow model using a standard code (Modflow). A pilot recharge plant. The simple model has been applied in different zones. The model has only 5 parameters. It evaluates the artificial recharge by means of the depletion coefficient. The model was calibrated for a monthly time-step, although the water balances in the soil and in the aquifer were calculated daily. The calibration the distributed parameter-flow model shows a high transmissivity, storage coefficient and porosity. The pilot recharge plant is a trench with recharge wells within it. The water available for recharge is obtained from an irrigation canal. A network of control points has been established to monitor the piezometric levels. The results obtained show a high storage coefficient and porosity. These parameters show a rapid groundwater velocity. Finally, the paper compares and contrasts the results obtained with the simple model, distributed parameter- flow model and the pilot recharge plant. The results are quite similar. The groundwater velocity is rapid. Water remains in the aquifer for a few days before returning to the river. (Author)

  14. Obtaining of ceramics biphasic dense and porous

    International Nuclear Information System (INIS)

    Pallone, E.M.J.A.; Rigo, E.C.S.; Fraga, A.F.

    2010-01-01

    Among the bioceramic hydroxyapatite (HAP) and beta-tricalcium phosphate (beta-TCP) are materials commonly used in biomedical field. Their combined properties result in a material with absorbable and at the same time with bioactive surface. Called biphasic ceramics such materials respond more quickly when exposed to physiological environment. In this work, powders of HAP/beta-TCP were obtained by chemical precipitation. After obtaining the post-phase was added at a ratio of 0, 15% and 30w% aqueous solutions of corn starch in order to obtain porous bodies. After mixing the resulting solutions were dried, resigned in tablet form and sintered at 1300 deg C. The initial powder was characterized by X-ray diffraction with Rietveld refinement to quantify the phases present. Bodies-of-evidence has been characterized by calculating the bulk density, X-ray diffraction (XRD), scanning electron microscopy and diametral compression. (author)

  15. Results obtained in the intercomparison of dosimetry systems Total body organized by In 2012, the European Group for radiation dosimetry (EURADOS) has organized an intercomparison of systems; Resultados obtenidos en la intercomparacion de sistemas dosimetricos de cuerpo entero organizada pro Eurados (IC2012)

    Energy Technology Data Exchange (ETDEWEB)

    Casal Zamorano, E.; Soriano Cruz, A.; Alabau Albors, J.; Palma Copete, J. D.

    2013-07-01

    dosimetric full-length for photons, within the action on {sup h}armonization of the monitoring Individual of the radiation External{sup e}stablished by the group. 88 dosimetric systems, 75 30 institutions have participated in the intercomparison countries. Each participant has sent a group of 26 dosimeters which have been irradiated with various doses and radiation qualities. The overall results of the intercomparison were presented recently (1). This communication presents the results obtained by our Center. EURADOS (IC2012). (Author)

  16. Obtainment of tantalum oxide from national ores

    International Nuclear Information System (INIS)

    Pinatti, D.G.; Ribeiro, S.; Martins, A.H.

    1988-01-01

    The experimental results of tantalum oxides (Ta 2 O 5 ) obtainment from Brazilian ores of tantalite and columbite are described. This study is a part of the technologic and scientific research design of refractory metals (Ti, Zr, Hf, V, Nb, Ta, Cr, Mo and W) and correlate ceramics. (C.G.C.) [pt

  17. Annual report on major results and progress of Naka Fusion Research Establishment of JAERI from April 1 to September 30, 2005 and Fusion Research and Development Directorate of JAEA from October 1, 2005 to March 31, 2006

    International Nuclear Information System (INIS)

    Yoshida, Hidetoshi; Oasa, Kazumi; Hayashi, Takao; Nakamura, Hiroo; Ogawa, Hiroaki

    2006-09-01

    This annual report provides an overview of major results and progress on research and development (R and D) activities at Naka Fusion Research Establishment of Japan Atomic Energy Research Institute (JAERI) during the period from April 1 to September 30, 2005 and at Fusion Research and Development Directorate of Japan Atomic Energy Agency (JAEA) from October 1, 2005 to March 31, 2006, including those performed in collaboration with other research establishments of JAERI, research institutes, and universities. In JT-60, ferritic steel tiles (FSTs) were installed inside the vacuum vessel of JT-60U to reduce the toroidal field ripple. After the installation of FSTs, a high normalized beta plasma at β N ∼2.3 was sustained for 28.6s with ELMy H-mode confinement as required for an ITER hybrid operation scenario. National Centralized Tokamak was placed as the ITER satellite tokamak in collaboration with the EU fusion community, and the facility design was modified strongly in support of ITER. In theoretical and analytical researches, studies on H-mode confinement, ITB in reversed shear plasmas, aspect ratio effects on external MHD modes and magnetic island evolution in a rotating plasma were progressed. Progress was also made in the NEXT project in which the behaviors of collisionless MHD modes and the dynamics of zonal flows were simulated. In fusion reactor technologies, R and Ds for ITER and fusion DEMO plants have been carried out. For ITER, a steady state operation of the 170GHz gyrotron up to 1000 s with 0.2 MW was demonstrated. Also current density of the neutral beam injector has been extended to 134A/m 2 at 0.75MeV. In the ITER Test Blanket Module (TBM), designs of Water and Helium Cooled Solid Breeder TBMs and R and Ds of tritium breeder/multiplier materials were progressed. Tritium processing technology for breeding blankets was also progressed. For the DEMO reactors, high temperature superconductor such as Bi2212 has been examined. In plasma facing

  18. Majorization uncertainty relations for mixed quantum states

    Science.gov (United States)

    Puchała, Zbigniew; Rudnicki, Łukasz; Krawiec, Aleksandra; Życzkowski, Karol

    2018-04-01

    Majorization uncertainty relations are generalized for an arbitrary mixed quantum state ρ of a finite size N. In particular, a lower bound for the sum of two entropies characterizing the probability distributions corresponding to measurements with respect to two arbitrary orthogonal bases is derived in terms of the spectrum of ρ and the entries of a unitary matrix U relating both bases. The results obtained can also be formulated for two measurements performed on a single subsystem of a bipartite system described by a pure state, and consequently expressed as an uncertainty relation for the sum of conditional entropies.

  19. Personality, academic majors and performance

    DEFF Research Database (Denmark)

    Vedel, Anna; Thomsen, Dorthe Kirkegaard; Larsen, Lars

    2015-01-01

    Personality–performance research typically uses samples of psychology students without questioning their representativeness. The present article reports two studies challenging this practice. Study 1: group differences in the Big Five personality traits were explored between students (N = 1067......) in different academic majors (medicine, psychology, law, economics, political science, science, and arts/humanities), who were tested immediately after university enrolment. Study 2: six and a half years later the students’ academic records were obtained, and predictive validity of the Big Five personality...... traits and their subordinate facets was examined in the various academic majors in relation to Grade Point Average (GPA). Significant group differences in all Big Five personality traits were found between students in different academic majors. Also, variability in predictive validity of the Big Five...

  20. ACTIVATED CARBON (CHARCOAL OBTAINING . APPLICATION

    Directory of Open Access Journals (Sweden)

    Florin CIOFU

    2015-05-01

    Full Text Available The activated carbon is a microporous sorbent with a very large adsorption area that can reach in some cases even 1500sqm / gram. Activated carbon is produced from any organic material with high carbon content: coal, wood, peat or moor coal, coconut shells. The granular activated charcoal is most commonly produced by grinding the raw material, adding a suitable binder to provide the desired hardness and shape. Enabling coal is a complete process through which the raw material is fully exposed to temperatures between 600-900 degrees C, in the absence of oxygen, usually in a domestic atmosphere as gases such as nitrogen or argon; as material that results from this process is exposed in an atmosphere of oxygen and steam at a temperature in the interval from 600 - 1200 degrees C.

  1. Glasses obtained from industrial wastes

    International Nuclear Information System (INIS)

    Bortoluzzi, D.; Oliveira Fillho, J.; Uggioni, E.; Bernardin, A.M.

    2009-01-01

    This paper deals with the study of the vitrification mechanism as an inertization method for industrial wastes contaminated with heavy metals. Ashes from coal (thermoelectric), wastes from mining (fluorite and feldspar) and plating residue were used to compose vitreous systems planed by mixture design. The chemical composition of the wastes was determined by XRF and the formulations were melted at 1450 deg C for 2h using 10%wt of CaCO 3 (fluxing agent). The glasses were poured into a mold and annealed (600 deg C). The characteristic temperatures were determined by thermal analysis (DTA, air, 20 deg C/min) and the mechanical behavior by Vickers microhardness. As a result, the melting temperature is strongly dependent on silica content of each glass, and the fluorite residue, being composed mainly by silica, strongly affects Tm. The microhardness of all glasses is mainly affected by the plating residue due to the high iron and zinc content of this waste. (author)

  2. The preliminary result of the δ65Cu and δ34S values of major ore minerals in the Erdenetiin-Ovoo Cu-Mo porphyry deposit, Northern Mongolia

    Science.gov (United States)

    KIM, Y.; Lee, I.; Oyungerel, S.; Jargal, L.; Tsedenbal, T.; Ryu, J. S.

    2016-12-01

    The copper isotope (δ65Cu) and sulfur isotope (δ34S) compositions of major ore minerals from the Erdenetiin-Ovoo Cu-Mo porphyry deposit were measured to trace sources of copper and sulfur, and to evaluate the precipitation environment of ore minerals. The major ore minerals are pyrite, chalcopyrite, molybdenite and chalcocite developed in the QSP (Quartz-Sericite-Pyrite) alteration zone. The sulfide minerals such as sphalerite and covellite, and carbonate ore minerals like malachite, azurite are also identified. The copper isotope ratios (65Cu/63Cu) of copper ore minerals (chalcopyrite, chalcocite, malachite, azurite, covellite and chrysocolla) were analyzed by the MC-ICPMS in KBSI located in Ochang, South Korea. The measured δ65Cu values relative to NIST 976 range from -1.01 ‰ to 5.76 ‰. The average δ65Cu values of sulfide minerals such as chalcopyrite (1.03 ‰), chalcocite (0.62 ‰) and covellite (0.51 ‰) seem to be relatively lower than those of carbonate and silicate Cu minerals such as malachite (0.24 ‰), azurite (2.17 ‰) and chrysocolla (5.76 ‰). The sulfur isotope ratios (34S/32S) of major sulfide minerals were measured by EA-CF-IRMS (Elemental Analyzer - Continuous Flow - Isotope Ratio Mass Spectrometer) in NCIRF, Seoul National University. The average δ34SV-CDT value is -1.1 ‰ indicating the magmatic signature of sulfur. There is the difference of δ34S values between sulfide minerals. While the δ34S values of pyrite, chalcopyrite and molybdenite range from -0.9 to 0.8 ‰, the δ34S values of chalcocite range from -2.6 ‰ to -1.4 ‰. These lower values might be attributed to the sulfur isotope fractionation during its precipitation.

  3. Organoclays obtaining starting up of clays sodium

    International Nuclear Information System (INIS)

    Silva, M.M. da; Mota, M.F.; Oliveira, G.C. de; Rodrigues, M.G.F.

    2012-01-01

    Clays have several applications in many areas of fields of technology, however, modification of these materials using organic compounds can be performed to obtain further hydrophobic materials, for applications in the adsorption of organic pollutants. This study aimed to analyze the effects of modifying two clays using sodium quaternary ammonium surfactants through ion exchange reaction process, in obtaining organoclays. The samples with sodium and organoclays were characterized by the techniques of X-ray diffraction (XRD), Infrared Spectroscopy in the region (IV), Gravimetric and Differential Thermal Analysis (DTA / TG) and organic adsorption tests. The results show that the process of obtaining organoclay is efficient, and materials have the potential for future applications in removing organic contaminants. (author)

  4. Prospects after Major Trauma

    NARCIS (Netherlands)

    Holtslag, H.R.

    2007-01-01

    Introduction. After patients survived major trauma, their prospects, in terms of the consequences for functioning, are uncertain, which may impact severely on patient, family and society. The studies in this thesis describes the long-term outcomes of severe injured patients after major trauma. In

  5. Major operations and activities

    Energy Technology Data Exchange (ETDEWEB)

    Black, D.G.

    1995-06-01

    This section of the 1994 Hanford Site Environmental Report summarizes the major operations and activities on the site. These operations and activities include site management, waste management, environmental restoration and corrective actions, and research and technology development.

  6. A major safety overhaul

    CERN Multimedia

    2003-01-01

    A redefined policy, a revamped safety course, an environmental project... the TIS (Technical Inspection and Safety) Division has begun a major safety overhaul. Its new head, Wolfgang Weingarten, explains to the Bulletin why and how this is happening.

  7. Allegheny County Major Rivers

    Data.gov (United States)

    Allegheny County / City of Pittsburgh / Western PA Regional Data Center — This dataset contains locations of major rivers that flow through Allegheny County. These shapes have been taken from the Hydrology dataset. The Ohio River,...

  8. Major operations and activities

    International Nuclear Information System (INIS)

    Black, D.G.

    1995-01-01

    This section of the 1994 Hanford Site Environmental Report summarizes the major operations and activities on the site. These operations and activities include site management, waste management, environmental restoration and corrective actions, and research and technology development

  9. Never, non-daily, and daily smoking status and progression to daily cigarette smoking as correlates of major depressive episode in a national sample of youth: Results from the National Survey of Drug Use and Health 2013 to 2015.

    Science.gov (United States)

    Cohn, Amy M

    2018-09-01

    Cigarette smoking is associated with depression, and new initiates who progress more quickly to daily smoking may be at enhanced risk. In a nationally representative sample of youth, this study examined the association between daily, non-daily, and never smoking with past-year and lifetime major depressive episode (MDE) and, among daily smokers, whether faster progression to daily smoking was associated with increased MDE risk. Data were from n = 44,921 youth aged 12-17 in the 2013-2015 National Survey on Drug Use and Health. Weighted adjusted multivariable logistic regression models were used to examine the association of smoking status (daily, non-daily, never) with lifetime and past-year MDE, and the association between progression from cigarette trial to daily smoking with MDE outcomes among daily smokers. Daily and non-daily smokers had similar rates of lifetime and past-year MDE; rates of MDE were approximately 50% lower among never smokers. Compared to never smokers, adjusted models showed that non-daily smokers had a higher risk of past-year and lifetime MDE, while daily smokers had a higher risk of past-year but not lifetime MDE. Daily smoking youth who progressed more quickly from cigarette trial to daily use had an increased risk of both lifetime and past-year MDE. Prevention programs should target factors associated with the shift from cigarette experimentation to regular use to curb deleterious consequences of use. Copyright © 2018. Published by Elsevier Ltd.

  10. Stenting of major airway constriction

    International Nuclear Information System (INIS)

    Wu Xiaomei

    2002-01-01

    Objective: To investigate the correlated issues in the stenting treatment of major airway constriction. Methods: Nineteen cases of major airway stenting procedure were studied retrospectively. The clinical choice of stents of different advantages or deficiencies were discussed. The importance of intravenous anesthesia supporting, life-parameters monitoring during the procedures and the prevention of complications were analysed. Results: Under intravenous and local anesthesia, 19 Wallstents had been successively placed and relieved 19 cases of major airway constrictions due to malignant or benign diseases (15 of tumors, 3 of tuberculosis, 1 of tracheomalacia). Intravenous anesthesia and life-parameters monitoring had made the procedures more safe and precise. Conclusions: Major airway stenting is an reliable method for relieving tracheobronchial stenosis; and intravenous anesthesia supporting and life-parameters monitoring guarantee the satisfactions of procedures

  11. Purification of alcohol obtained from molasses

    Energy Technology Data Exchange (ETDEWEB)

    Visnevskaya, G L; Egorov, A S; Sokol' skaya, E V

    1960-01-01

    A study of the composition of alcohol liquids on different plates of a fractionation column of indirect action during purification of alcohol obtained from normal and defective molasses, and from starch raw material, showed that there were two local strength minima in the lower part of the column and on the plates (adjacent and feed). Aldehydes behaved as a typical head impurity; a noticeable increase in their concentration occurred only on the highest plates in the fractionation column. In the zone of the column containing liquids of a strength of 86 to 94% alcohol by weight a sharply pronounced local maximum of ester accumulation were observed, provisionally designated as intermediate, whose presence is apparently one of the causes of the specific sharp taste of alcohol obtained from molasses. These esters hinder the obtaining of high-grade alcohols which are standard in respect to ester content and oxidizability test. Reduction with 0.05N KMnO/sub 4/ occurs most rapidly with alcohol liquids in the zone of ester accumulation; purification of alcohols obtained from grain and potato raw material resulted in no zones of ester accumulation in the column.

  12. Effect of major lifestyle risk factors, independent and jointly, on life expectancy with and without cardiovascular disease: results from the Consortium on Health and Ageing Network of Cohorts in Europe and the United States (CHANCES).

    Science.gov (United States)

    O'Doherty, Mark G; Cairns, Karen; O'Neill, Vikki; Lamrock, Felicity; Jørgensen, Torben; Brenner, Hermann; Schöttker, Ben; Wilsgaard, Tom; Siganos, Galatios; Kuulasmaa, Kari; Boffetta, Paolo; Trichopoulou, Antonia; Kee, Frank

    2016-05-01

    Seldom have studies taken account of changes in lifestyle habits in the elderly, or investigated their impact on disease-free life expectancy (LE) and LE with cardiovascular disease (CVD). Using data on subjects aged 50+ years from three European cohorts (RCPH, ESTHER and Tromsø), we used multi-state Markov models to calculate the independent and joint effects of smoking, physical activity, obesity and alcohol consumption on LE with and without CVD. Men and women aged 50 years who have a favourable lifestyle (overweight but not obese, light/moderate drinker, non-smoker and participates in vigorous physical activity) lived between 7.4 (in Tromsø men) and 15.7 (in ESTHER women) years longer than those with an unfavourable lifestyle (overweight but not obese, light/moderate drinker, smoker and does not participate in physical activity). The greater part of the extra life years was in terms of "disease-free" years, though a healthy lifestyle was also associated with extra years lived after a CVD event. There are sizeable benefits to LE without CVD and also for survival after CVD onset when people favour a lifestyle characterized by salutary behaviours. Remaining a non-smoker yielded the greatest extra years in overall LE, when compared to the effects of routinely taking physical activity, being overweight but not obese, and drinking in moderation. The majority of the overall LE benefit is in disease free years. Therefore, it is important for policy makers and the public to know that prevention through maintaining a favourable lifestyle is "never too late".

  13. The day-to-day acute effect of wake therapy in patients with major depression using the HAM-D6 as primary outcome measure: results from a randomised controlled trial.

    Directory of Open Access Journals (Sweden)

    Klaus Martiny

    Full Text Available This paper reports day-to-day data for from a one-week intervention phase, part of a 9-weeks randomised parallel study with patient having major depression (data from weekly visits have been reported. Wake therapy (sleep deprivation has an established antidepressant effect with onset of action within hours. Deterioration on the following night's sleep is, however, common, and we used daily light therapy and sleep time stabilisation as a preventive measure. In particular, we evaluated the day-to-day acute effect of and tolerance to sleep deprivation and examined predictors of response.Patients were assessed at psychiatric inpatient wards. In the wake group (n = 36, patients did three wake therapies in combination with light therapy each morning together with sleep time stabilisation. In the exercise group (n = 38, patients did daily exercise. Hamilton subscale scores were primary outcome (not blinded, secondary outcome was self-assessment data from the Preskorn scale and sleep.Patients in the wake therapy group had an immediate, large, stable, and statistically significant better antidepressant effect than patients in the exercise group with response rates at day5 of 75.0%/25.1% and remission rates of 58.6%/6.0%, respectively. The response and remission rates were diminished at day8 with response rates of 41.9%/10.1% and remission rates of 19.4%/4.7%, respectively. Patients and ward personnel found the method applicable with few side effects. Positive diurnal variation (mood better in the evening predicted a larger response to wake therapy. In the wake group napping on days after intervention predicted greater deterioration on day8.The intervention induced an acute antidepressant response without relapse between wake nights but with a diminishing effect after intervention. Development is still needed to secure maintenance of response. Avoiding napping in the days after wake therapy is important.Clinical trials.gov NCT00149110.

  14. Prognostic value of myocardial perfusion single photon emission computed tomography for major adverse cardiac cerebrovascular and renal events in patients with chronic kidney disease: results from first year of follow-up of the Gunma-CKD SPECT multicenter study

    Energy Technology Data Exchange (ETDEWEB)

    Kasama, Shu [Gunma University Graduate School of Medicine, Department of Medicine and Biological Science (Cardiovascular Medicine), Maebashi, Gunma (Japan); Cardiovascular Hospital of Central Japan (Kitakanto Cardiovascular Hospital), Department of Cardiovascular Medicine, Gunma (Japan); Toyama, Takuji [Department of Cardiovascular Medicine, Gunma Prefectural Cardiovascular Center, Maebashi (Japan); Sato, Makito [Gunma University Graduate School of Medicine, Department of Medicine and Biological Science (Cardiovascular Medicine), Maebashi, Gunma (Japan); Tatebayashi Kosei Hospital, Department of Internal Medicine, Gunma (Japan); Sano, Hirokazu [Gunma University Graduate School of Medicine, Department of Medicine and Biological Science (Cardiovascular Medicine), Maebashi, Gunma (Japan); Isesaki Municipal Hospital, Department of Cardiovascular Medicine, Isesaki (Japan); Ueda, Tetsuya [Fujioka General Hospital, Division of Cardiology, Fujioka (Japan); Sasaki, Toyoshi [Takasaki General Medical Center, Division of Cardiology, Takasaki (Japan); Nakahara, Takehiro; Kurabayashi, Masahiko [Gunma University Graduate School of Medicine, Department of Medicine and Biological Science (Cardiovascular Medicine), Maebashi, Gunma (Japan); Higuchi, Tetsuya; Tsushima, Yoshito [Gunma University Graduate School of Medicine, Department of Diagnostic Radiology and Nuclear Medicine, Maebashi (Japan)

    2016-02-15

    Patients with chronic kidney disease (CKD) have an increased risk of adverse cardio-cerebrovascular events. We examined whether stress myocardial perfusion single photon emission computed tomography (SPECT) provides reliable prognostic markers for these patients. In this multicenter, prospective cohort trial from the Gunma-CKD SPECT study protocol, patients with CKD [estimated glomerular filtration rate (eGFR) < 60 min/ml per 1.73 m{sup 2}] undergoing stress {sup 99m}Tc-tetrofosmin SPECT for suspected or possible ischemic heart disease were initially followed for 1 year, with the following study endpoints: primary, the occurrence of cardiac deaths (CDs), and secondary, major adverse cardiac, cerebrovascular, and renal events (MACCREs). The summed stress score (SSS), summed rest score, and summed difference score (SDS) were estimated with the standard 17-segment, 5-point scoring model. Left ventricular end-diastolic volume, end-systolic volume (ESV), and ejection fraction were measured using electrocardiogram-gated SPECT. During the first year of follow-up, 69 of 299 patients experienced MACCREs (CD, n = 7; non-fatal myocardial infarction, n = 3; hospitalization for heart failure, n = 13; cerebrovascular accident, n = 1; need for revascularization, n = 38; and renal failure, i.e., hemodialysis initiation, n = 7). ESV and SSS were associated with CDs (p < 0.05), and eGFR and SDS were associated with MACCREs (p < 0.05), in multivariate logistic analysis. Patients with high ESV and high SSS had a significantly higher CD rate during the first year than the other CKD patient subgroups (p < 0.05). Patients with low eGFR and high SDS had a significantly higher MACCRE rate than the other subgroups (p < 0.05). Myocardial perfusion SPECT can provide reliable prognostic markers for patients with CKD. (orig.)

  15. Prognostic value of myocardial perfusion single photon emission computed tomography for major adverse cardiac cerebrovascular and renal events in patients with chronic kidney disease: results from first year of follow-up of the Gunma-CKD SPECT multicenter study

    International Nuclear Information System (INIS)

    Kasama, Shu; Toyama, Takuji; Sato, Makito; Sano, Hirokazu; Ueda, Tetsuya; Sasaki, Toyoshi; Nakahara, Takehiro; Kurabayashi, Masahiko; Higuchi, Tetsuya; Tsushima, Yoshito

    2016-01-01

    Patients with chronic kidney disease (CKD) have an increased risk of adverse cardio-cerebrovascular events. We examined whether stress myocardial perfusion single photon emission computed tomography (SPECT) provides reliable prognostic markers for these patients. In this multicenter, prospective cohort trial from the Gunma-CKD SPECT study protocol, patients with CKD [estimated glomerular filtration rate (eGFR) < 60 min/ml per 1.73 m 2 ] undergoing stress 99m Tc-tetrofosmin SPECT for suspected or possible ischemic heart disease were initially followed for 1 year, with the following study endpoints: primary, the occurrence of cardiac deaths (CDs), and secondary, major adverse cardiac, cerebrovascular, and renal events (MACCREs). The summed stress score (SSS), summed rest score, and summed difference score (SDS) were estimated with the standard 17-segment, 5-point scoring model. Left ventricular end-diastolic volume, end-systolic volume (ESV), and ejection fraction were measured using electrocardiogram-gated SPECT. During the first year of follow-up, 69 of 299 patients experienced MACCREs (CD, n = 7; non-fatal myocardial infarction, n = 3; hospitalization for heart failure, n = 13; cerebrovascular accident, n = 1; need for revascularization, n = 38; and renal failure, i.e., hemodialysis initiation, n = 7). ESV and SSS were associated with CDs (p < 0.05), and eGFR and SDS were associated with MACCREs (p < 0.05), in multivariate logistic analysis. Patients with high ESV and high SSS had a significantly higher CD rate during the first year than the other CKD patient subgroups (p < 0.05). Patients with low eGFR and high SDS had a significantly higher MACCRE rate than the other subgroups (p < 0.05). Myocardial perfusion SPECT can provide reliable prognostic markers for patients with CKD. (orig.)

  16. Investigation of major phenolic antioxidants from Camellia sinensis fruits

    Directory of Open Access Journals (Sweden)

    Ajay Rana

    2015-12-01

    Full Text Available The present study unveils major phenolic antioxidant compounds from Camellia sinensis fruits, followed by their investigation, purification and characterization using HPLC, ESI-MS and NMR studies. The spectrophotometric estimation results have clearly demonstrated that C. sinensis (tea fruits contain up to 14% of total polyphenols (as gallic acid equivalent and 7% of flavonoids (as quercetin equivalent on dry weight basis. Differential solvent-mediated extractions have been performed for quantitative assessment of major phytoconstituents by RP-HPLC analysis. And the results have revealed that these fruits contain adequate amount of tea catechins (4% along with caffeine (1% and theanine (0.4% on dry weight basis. Moreover, purification and characterization of major phytoconstituents such as epigallocatechin, epicatechin, epigallocatechin gallate and epicatechin gallate along with caffeine have been accomplished. Thus, it is clearly demonstrated that tea fruits could act as a possible and reliable source for obtaining major phenolic antioxidants.

  17. Major Decisions: Motivations for Selecting a Major, Satisfaction, and Belonging

    Science.gov (United States)

    Soria, Krista M.; Stebleton, Michael

    2013-01-01

    In this paper, we analyzed the relationship between students' motivations for choosing academic majors and their satisfaction and sense of belonging on campus. Based on a multi-institutional survey of students who attended large, public, research universities in 2009, the results suggest that external extrinsic motivations for selecting a major…

  18. Major international sport profiles.

    Science.gov (United States)

    Patel, Dilip R; Stier, Bernhard; Luckstead, Eugene F

    2002-08-01

    Sports are part of the sociocultural fabric of all countries. Although different sports have their origins in different countries, many sports are now played worldwide. International sporting events bring athletes of many cultures together and provide the opportunity not only for athletic competition but also for sociocultural exchange and understanding among people. This article reviews five major sports with international appeal and participation: cricket, martial arts, field hockey, soccer, and tennis. For each sport, the major aspects of physiological and biomechanical demands, injuries, and prevention strategies are reviewed.

  19. Edaphic macrofauna as biological indicator of the conservation/disturbance status of soil. Results obtained in Cuba; La macrofauna edáfica como indicador biológico del estado de conservación/perturbación del suelo. Resultados obtenidos en Cuba

    Energy Technology Data Exchange (ETDEWEB)

    Cabrera, Grisel [Instituto de Ecología y Sistemática, CITMA. Carretera de Varona km 3 1/2 Capdevila, Boyeros, La Habana 19 CP 11900 (Cuba)

    2012-07-01

    In order to predict the degradation status of a soil, a group of variables comprising its physical, chemical and/or biological properties is used. Macrofauna, which includes soil invertebrates higher than 2 mm of diameter, is a biological component that can be used for such purpose. Its taxonomic richness as well as its density, biomass and functional composition change depending on the effect of diverse land uses and managements. This review reaffirms that the macrofauna characteristics and the results obtained, mainly in Cuba, about its variation in ecosystems with different anthropization levels, support the potential use of this fauna as biological indicator of the soil's conservation status. Future studies should consider a lower taxonomic level in the identification of macrofauna, and relate its taxonomic and functional composition to the climate and pedological factors. (author)

  20. Major New Initiatives

    Indian Academy of Sciences (India)

    First page Back Continue Last page Overview Graphics. Major New Initiatives. Multi-party multi-rate video conferencing OOPS. Live Lecture OOPS. Rural ATM Machine Vortex. Finger print detection HP-IITM. Medical Diagnostic kit NeuroSynaptic. LCD projection system TeNeT. Web Terminal MeTeL Midas. Entertainment ...

  1. Major planning enquiries

    Energy Technology Data Exchange (ETDEWEB)

    Shore, P

    1978-11-01

    This is a speech delivered by the U.K. Secretary of State for the Environment in Manchester (UK) on September 13th 1978. It outlines the Minister's views on the role and significance of major planning inquiries - such as that proposed to be held on the Commercial Demonstration Fast Reactor. (CDFR) (author).

  2. Major Biomass Conference

    Science.gov (United States)

    Top Scientists, Industry and Government Leaders to Gather for Major Biomass Conference America, South America and Europe will focus on building a sustainable, profitable biomass business at the Third Biomass Conference of the Americas in Montreal. Scheduled presentations will cover all biomass

  3. Unity in Major Themes

    DEFF Research Database (Denmark)

    Booss-Bavnbek, Bernhelm; Davis, Philip J.

    We describe and explain the desire, common among mathematicians, both for unity and independence in its major themes. In the dialogue that follows, we express our spontaneous and considered judgment and reservations; by contrasting the development of mathematics as a goal-driven process as opposed...

  4. Understanding Business Majors' Learning Styles

    Science.gov (United States)

    Giordano, James; Rochford, Regina A.

    2005-01-01

    Recently, business education programs have experienced a decline in enrollment and an increase in attrition. To understand these issues and recommend solutions, the learning styles of 503 first-year business majors at an urban community college were examined. The results demonstrated that: (a) 94% of the participants were analytic learners; (b)…

  5. Lifetime obtained by ion beam assisted deposition

    Energy Technology Data Exchange (ETDEWEB)

    Chakaroun, M. [XLIM-MINACOM-UMR 6172, Faculte des Sciences et Techniques, 123 av. Albert Thomas, 87060 Limoges cedex (France); Antony, R. [XLIM-MINACOM-UMR 6172, Faculte des Sciences et Techniques, 123 av. Albert Thomas, 87060 Limoges cedex (France)], E-mail: remi.antony@unilim.fr; Taillepierre, P.; Moliton, A. [XLIM-MINACOM-UMR 6172, Faculte des Sciences et Techniques, 123 av. Albert Thomas, 87060 Limoges cedex (France)

    2007-09-15

    We have fabricated green organic light-emitting diodes based on tris-(8-hydroxyquinoline)aluminium (Alq3) thin films. In order to favor the charge carriers transport from the anode, we have deposited a N,N'-diphenyl-N,N'-bis (3-methylphenyl)-1,1'-diphenyl-4,4'-diamine (TPD) layer (hole transport layer) on a ITO anode. Cathode is obtained with a calcium layer covered with a silver layer. This silver layer is used to protect the other layers against oxygen during the OLED use. All the depositions are performed under vacuum and the devices are not exposed to air during their realisation. In order to improve the silver layer characteristics, we have realized this layer with the ion beam assisted deposition process. The aim of this process is to densify the layer and then reduce the permeation of H{sub 2}O and O{sub 2}. We have used argon ions to assist the silver deposition. All the OLEDs optoelectronic characterizations (I = f(V), L = f(V)) are performed in the ambient air. We compare the results obtained with the assisted layer with those obtained with a classical cathode realized by thermal unassisted evaporation. We have realized lifetime measurements in the ambient air and we discuss about the assisted layer influence on the OLEDs performances.

  6. Economic evaluation of a guided and unguided internet-based CBT intervention for major depression: Results from a multi-center, three-armed randomized controlled trial conducted in primary care.

    Directory of Open Access Journals (Sweden)

    Pablo Romero-Sanchiz

    Full Text Available Depression is one of the most common mental disorders and will become one of the leading causes of disability in the world. Internet-based CBT programs for depression have been classified as "well established" following the American Psychological Association criteria for empirically supported treatments. The aim of this study is to analyze the cost effectiveness at 12-month follow-up of the Internet-based CBT program "Smiling is fun" with (LITG and without psychotherapist support (TSG compared to usual care. The perspective used in our analysis is societal. A sample of 296 depressed patients (mean age of 43.04 years; 76% female; BDI-II mean score = 22.37 from primary care services in four Spanish regions were randomized in the RCT. The complete case and intention-to-treat (ITT perspectives were used for the analyses. The results demonstrated that both Internet-based CBT interventions exhibited cost utility and cost effectiveness compared with a control group. The complete case analyses revealed an incremental cost-effectiveness ratio (ICER of €-169.50 and an incremental cost-utility ratio (ICUR of €-11389.66 for the TSG group and an ICER of €-104.63 and an ICUR of €-6380.86 for the LITG group. The ITT analyses found an ICER of €-98.37 and an ICUR of €-5160.40 for the TSG group and an ICER of €-9.91 and an ICUR of €496.72 for the LITG group. In summary, the results of this study indicate that the two Internet-based CBT interventions are appropriate from both economic and clinical perspectives for depressed patients in the Spanish primary care system. These interventions not only help patients to improve clinically but also generate societal savings.clinicaltrials.gov NCT01611818.

  7. The effects of land use on fluvial sediment chemistry for the conterminous U.S. - results from the first cycle of the NAWQA Program: trace and major elements, phosphorus, carbon, and sulfur.

    Science.gov (United States)

    Horowitz, Arthur J; Stephens, Verlin C

    2008-08-01

    In 1991, the U.S. Geological Survey (USGS) began the first cycle of its National Water Quality Assessment (NAWQA) Program. The Program encompassed 51 river basins that collectively accounted for more than 70% of the total water use (excluding power generation), and 50% of the drinking water supply in the U.S. The basins represented a variety of hydrologic settings, rock types (geology), land-use categories, and population densities. One aspect of the first cycle included bed sediment sampling; sites were chosen to represent baseline and important land-use categories (e.g., agriculture, urban) in each basin. In total, over 1200 bed sediment samples were collected. All samples were size-limited (or=95% of the concentrations present), rather than total-recoverable chemical data. Land-use percentages, upstream underlying geology, and population density were determined for each site and evaluated to asses their relative influence on sediment chemistry. Baseline concentrations for the entire U.S. also were generated from a subset of all the samples, and are based on material collected from low population (sediment chemistry. The only land-use category that appears to substantially affect sediment chemistry is percent urban, and this result is mirrored by population density; in fact, the latter appears more consistent than the former.

  8. Proximity of US schools to major roadways: a nationwide assessment.

    Science.gov (United States)

    Kingsley, Samantha L; Eliot, Melissa N; Carlson, Lynn; Finn, Jennifer; MacIntosh, David L; Suh, Helen H; Wellenius, Gregory A

    2014-01-01

    Long-term exposure to traffic pollution has been associated with adverse health outcomes in children and adolescents. A significant number of schools may be located near major roadways, potentially exposing millions of children to high levels of traffic pollution, but this hypothesis has not been evaluated nationally. We obtained data on the location and characteristics of 114,644 US public and private schools, grades prekindergarten through 12, and calculated their distance to the nearest major roadway. In 2005-2006, 3.2 million students (6.2%) attended 8,424 schools (7.3%) located within 100 m of a major roadway, and an additional 3.2 million (6.3%) students attended 8,555 (7.5%) schools located 100-250 m from a major roadway. Schools serving predominantly Black students were 18% (95% CI, 13-23%) more likely to be located within 250 m of a major roadway. Public schools eligible for Title I programs and those with a majority of students eligible for free/reduced price meals were also more likely to be near major roadways. In conclusion, 6.4 million US children attended schools within 250 m of a major roadway and were likely exposed to high levels of traffic pollution. Minority and underprivileged children were disproportionately affected, although some results varied regionally.

  9. Characterization of Wastewaters obtained from Hatay Tanneries

    Directory of Open Access Journals (Sweden)

    Şana Sungur

    2017-06-01

    Full Text Available The leather tanning industry is one of the most significant pollutants in terms of both conventional and toxic parameters. On the other hand, leather industry has an important economic role both in Turkey and in the World. In this study, wastewater samples were taken from 15 different tanneries in the Hatay Region. Wastewaters obtained from liming process and chromium tanning process was analyzed. Sulfide, chromium (III, chromium (VI, oil and grease, total suspended solids (TSS, organic matters, biochemical oxygen demand (BOD, chemical oxygen demand (COD, pH and alkalinity were determined according to Turkish Standard Methods. The determined averages values belong to wastewaters obtained from liming process were as following: pH 11.71; COD 16821 mg L-1; BOD 4357 mg L-1; TSS 39023 mg L-1; oil and grease 364 mg L-1; S-2 concentration 802 mg L-1; alkalinity 2115 mg L-1. The determined averages values belong to wastewaters obtained from chromium tanning process were also as following: pH 4.23; COD 6740 mg L-1; BOD 377 mg L-1; Cr+3 concentrations 372 mg L-1; Cr+6 concentrations 127 mg L-1; TSS 14553 mg L-1; oil and grease 343 mg L-1. The results of all analyzes were higher than wastewater discharge standards. As a result, it’s necessary to use more effective treatments in order to reduce the negative impacts of leather tanning industry that affect environment, natural water resources and at last human health and welfare.

  10. Cotton nanofibers obtained by different acid conditions

    International Nuclear Information System (INIS)

    Teixeira, Eliangela de M.; Oliveira, Caue Ribeiro de; Mattoso, Luiz H.C.; Correa, Ana Carolina; Palladin, Priscila

    2009-01-01

    The thermal stability of cellulose nanofibers is related to their application and especially to polymer processing which temperatures of processing are around 200 deg C. In this work, nanofibers of commercial cotton were obtained by acid hydrolysis employing different acids: sulfuric, hydrochloric and a mixture (2:1; sulfuric acid: hydrochloric acid).The morphology of the nanofibers were characterized by transmission microscopy (TEM), crystallinity by x-ray diffraction (XRD) and thermal stability in air atmosphere by thermogravimetric analysis (TGA). The results indicated a very similar morphology and crystallinity among them. The main differences were relative to aggregation state e and thermal stability. The aggregation state of the suspensions decreases in the order HCl 2 SO 4 :HCl 2 SO 4- . The hydrolysis with a mix of HCl and H 2 SO 4 resulted in cellulose nanofibers with higher thermal stability than those hydrolyzed with H 2 SO 4 . The hydrolysis employed with a mixture of sulphuric and hydrochloric acids also showed a better dispersion than those suspensions of nanofibers obtained by hydrolysis with only HCl. (author)

  11. The Future of the Teaching Profession from the Perspective of Students with a Major in Education

    Science.gov (United States)

    Céspedes, Jensy Campos; Gutiérrez, Walter Solano

    2017-01-01

    The article offers the results obtained in a study where, through the application of a survey and the development of a discussion forum with students from education majors, information about their perceptions with regard to four axes related to the future of the teaching profession was obtained, as follows: the teacher profile, the student…

  12. PbSe nanocubes obtained by high-energy milling

    Energy Technology Data Exchange (ETDEWEB)

    Rojas-Chavez, H., E-mail: hrojasc@ipn.mx [Centro de Investigacion en Ciencia Aplicada y Tecnologia Avanzada - IPN (Mexico); Reyes-Carmona, F. [Facultad de Quimica - UNAM (Mexico); Achimovicova, M. [Slovak Academy of Sciences, Institute of Geotechnics (Slovakia); Daneu, N. [Jozef Stefan Institute, Department for Nanostructured Materials (Slovenia); Jaramillo-Vigueras, D. [Centro de Investigacion e Innovacion Tecnologica - IPN (Mexico)

    2012-06-15

    In this study, PbSe nanocubes were obtained by high-energy milling, and their optical properties were investigated by measuring the UV-VIS-IR spectra in the range of 200-2,000 nm. The optical absorption of all samples showed a strong UV emission band at 1.45 eV. Previously, to obtain only PbSe nanocubes, an intermediate phase was identified, PbSeO{sub 3}. Although both PbSeO{sub 3} and PbSe were traced through this study, a major effort is devoted to characterize the latter. To trace how chemical transitions evolve from precursors to PbSe, X-ray diffraction and Rietveld refinement were carried out. Therefore, the following parameters were evaluated as a function of milling time: phase percentages, area-to-volume ratio, average crystallite dimensions, specific surface area, and morphology changes. To corroborate previous findings, nitrogen adsorption and transmission electron microscopy techniques were used. All the set experimental results unambiguously confirm that crystallites show a cubic morphology, with its average crystallite size distribution being around 24 nm.

  13. First results obtained about the hydrogeological behaviour of the Estana Lakes and their relation with Estopinan aquifer (Huesca, Spain); Primeros resultados obtenidos sobre el funcionamiento hidrogeologico de la Lagunas de Estana y su relacion con el acuifero de Estopinan (Huesca, Espana)

    Energy Technology Data Exchange (ETDEWEB)

    Perez, C.; Lamban, L. J.

    2009-07-01

    The study area is located in the Pyrenean Marginal Sierras. The main structural features are the Estopinan syncline, made of two permeable levels: Upper Cretaceous and Eocene, and the endo rheic karstic Lakes of Estana. In this work we present the first results obtained of the hydrogeochemical and isotopic ({delta}O{sup 1}8, {delta}H{sup 2} y H{sup 3}) groundwater description, made to determine, with other studies, the relation between Lakes of Estana and Estopinan syncline, as well as the general hydrological and hydrogeological functioning. This description allowed us to differentiate the groundwater main groups and to deduce qualitatively the chemical dominating processes, observing a larger regional chemical variability mainly attributed to the different permeable levels as well as mixing processes. On the other hand, there is exposed a geological cartography made in the surrounding area of the lakes, which suggest an improvement in the knowledge of the geology and hydrogeology of this area. (Author) 38 refs.

  14. Major Peripheral Nerve Injuries After Elbow Arthroscopy.

    Science.gov (United States)

    Desai, Mihir J; Mithani, Suhail K; Lodha, Sameer J; Richard, Marc J; Leversedge, Fraser J; Ruch, David S

    2016-06-01

    To survey the American Society for Surgery of the Hand membership to determine the nature and distribution of nerve injuries treated after elbow arthroscopy. An online survey was sent to all members of the American Society for Surgery of the Hand under an institutional review board-approved protocol. Collected data included the number of nerve injuries observed over a 5-year period, the nature of treatment required for the injuries, and the outcomes observed after any intervention. Responses were anonymous, and results were securely compiled. We obtained 372 responses. A total of 222 nerve injuries were reported. The most injured nerves reported were ulnar, radial, and posterior interosseous (38%, 22%, and 19%, respectively). Nearly half of all patients with injuries required operative intervention, including nerve graft, tendon transfer, nerve repair, or nerve transfer. Of the patients who sustained major injuries, those requiring intervention, 77% had partial or no motor recovery. All minor injuries resolved completely. Our results suggest that major nerve injuries after elbow arthroscopy are not rare occurrences and the risk of these injuries is likely under-reported in the literature. Furthermore, patients should be counseled on this risk because most nerve injuries show only partial or no functional recovery. With the more widespread practice of elbow arthroscopy, understanding the nature and sequelae of significant complications is critically important in ensuring patient safety and improving outcomes. Copyright © 2016 Arthroscopy Association of North America. Published by Elsevier Inc. All rights reserved.

  15. Safety of RBMK reactors: Major results and prospects

    International Nuclear Information System (INIS)

    Sidorenko, V.A.

    1996-01-01

    The paper considers the following issues: basic reasons for the advent of NPPs with RBMK reactors; the logic of identifying top-priority measures immediately after the accident; top-priority measures for improving the safety and reliability of NPPs with RBMK reactors; upgrading NPPs with RBMK reactors in compliance with the Norms; programmes for retrofitting and upgrading of NPPs of the ''Rosnergoatom'' Concern and progress with their implementation as of April 1996; the safety of RBMK plants and the programmes of its enhancement with regard to modern requirements in the light of national and international assessment; objective indicators of safety, reliability, and economic efficiency of NPPs with RBMK reactors; economics: rationale for continuing plants operation till the end of their design lifetime. 8 refs, 3 figs

  16. The major results of the PISC II Round Robin test

    International Nuclear Information System (INIS)

    Crutzen, S.

    1987-01-01

    The objectives of the PISC-II programme were: - To evaluate the effectiveness of NDT techniques either in use or being developed for the inspection of reactor pressure vessel components, with regard mainly to detecting and charaterising service-induced flaws. - To identify techniques for acceptance tests, pre-service inspection (PSI) and in-service inspection (ISI) which could be generally accepted, and - to bring the conclusions of the programme to the attention of the Code, Standard and Regulatory Bodies concerned with ISI. (orig./HP)

  17. Securing Major Events

    International Nuclear Information System (INIS)

    Loeoef, Susanna

    2013-01-01

    When asked why the IAEA should provide nuclear security support to countries that organize large public events, Nuclear Security Officer Sophia Miaw answers quickly and without hesitation. ''Imagine any major public event such as the Olympics, a football championship, or an Expo. If a dirty bomb were to be exploded at a site where tens of thousands of people congregate, the radioactive contamination would worsen the effects of the bomb, increase the number of casualties, impede a rapid emergency response, and cause long term disruption in the vicinity,'' she said. Avoiding such nightmarish scenarios is the driving purpose behind the assistance the IAEA offers States that host major sporting or other public events. The support can range from a single training course to a comprehensive programme that includes threat assessment, training, loaned equipment and exercises. The type and scope of assistance depends on the host country's needs. ''We incorporate nuclear security measures into their security plan. We don't create anything new,'' Miaw said

  18. Carbon nanofibers obtained from electrospinning process

    Science.gov (United States)

    Bovi de Oliveira, Juliana; Müller Guerrini, Lília; Sizuka Oishi, Silvia; Rogerio de Oliveira Hein, Luis; dos Santos Conejo, Luíza; Cerqueira Rezende, Mirabel; Cocchieri Botelho, Edson

    2018-02-01

    In recent years, reinforcements consisting of carbon nanostructures, such as carbon nanotubes, fullerenes, graphenes, and carbon nanofibers have received significant attention due mainly to their chemical inertness and good mechanical, electrical and thermal properties. Since carbon nanofibers comprise a continuous reinforcing with high specific surface area, associated with the fact that they can be obtained at a low cost and in a large amount, they have shown to be advantageous compared to traditional carbon nanotubes. The main objective of this work is the processing of carbon nanofibers, using polyacrylonitrile (PAN) as a precursor, obtained by the electrospinning process via polymer solution, with subsequent use for airspace applications as reinforcement in polymer composites. In this work, firstly PAN nanofibers were produced by electrospinning with diameters in the range of (375 ± 85) nm, using a dimethylformamide solution. Using a furnace, the PAN nanofiber was converted into carbon nanofiber. Morphologies and structures of PAN and carbon nanofibers were investigated by scanning electron microscopy, Raman Spectroscopy, thermogravimetric analyses and differential scanning calorimeter. The resulting residual weight after carbonization was approximately 38% in weight, with a diameters reduction of 50%, and the same showed a carbon yield of 25%. From the analysis of the crystalline structure of the carbonized material, it was found that the material presented a disordered structure.

  19. Experimental methodology for obtaining sound absorption coefficients

    Directory of Open Access Journals (Sweden)

    Carlos A. Macía M

    2011-07-01

    Full Text Available Objective: the authors propose a new methodology for estimating sound absorption coefficients using genetic algorithms. Methodology: sound waves are generated and conducted along a rectangular silencer. The waves are then attenuated by the absorbing material covering the silencer’s walls. The attenuated sound pressure level is used in a genetic algorithm-based search to find the parameters of the proposed attenuation expressions that include geometric factors, the wavelength and the absorption coefficient. Results: a variety of adjusted mathematical models were found that make it possible to estimate the absorption coefficients based on the characteristics of a rectangular silencer used for measuring the attenuation of the noise that passes through it. Conclusions: this methodology makes it possible to obtain the absorption coefficients of new materials in a cheap and simple manner. Although these coefficients might be slightly different from those obtained through other methodologies, they provide solutions within the engineering accuracy ranges that are used for designing noise control systems.

  20. Electrolytic Hydrogen obtaining by a photovoltaic source

    International Nuclear Information System (INIS)

    Pasculete, E.; Condrea, F.; Stanoiu, L.

    2005-01-01

    At present, the developed countries allocate large funds for the financing of some global programs for fundamental and applicative research for development of hydrogen non-conventional production technologies. One of these technologies is the photo-assisted electrolysis. This technology is adopted in the research, which results are presented in this paper. The experimental model includes as basic equipment 100 W photovoltaic source, electrolysis battery press filter type, control unit of the electric energy discharged, accumulator, hydrogen storage unit. Five types of material have been tested for the electrolysis cell diaphragm: asbestos; Netrom- unwoven material from fibers of polypropylene; ion changing composite membrane - polysulfone support with an active layer of sulfonated poly-sulfone (PSS/PSJ) and poly-sulfone support with an active layer of sulfonated poly-eter cetone (SPEEK/PSf); ion-exchange membrane made from sulfonated poly-eter cetone (SPEEK). The graphics and results from the test system are presented. The analysis of the experimental results lead to the establishment of the optimal configuration of battery and of the operational conditions of the assembly. The experimental results give the opportunity to obtain electrolytic hydrogen with a photovoltaic source, in an efficient system, and promote the Romanian research at a level of a demonstrative installation

  1. Obtaining shale oil suitable for lighting

    Energy Technology Data Exchange (ETDEWEB)

    Giraudel, M

    1851-11-12

    Treats with sulphuric acid and then with soda, obtaining 57 per cent of products suitable for lighting in place of the usual 35 to 40 per cent as obtained by present processes. The product has a less disagreeable odor.

  2. Polypropylene obtained through zeolite supported catalysts

    International Nuclear Information System (INIS)

    Bastos, Queli C.; Marques, Maria de Fatima V.

    2004-01-01

    Propylene polymerizations were carried out with φ 2 C(Flu)(Cp)ZrCl 2 and SiMe 2 (Ind)2ZrCl 2 catalysts supported on silica, zeolite sodic mordenite (NaM) and acid mordenite (HM). The polymerizations were performed at different temperatures and varying aluminium/zirconium molar ratios ([Al]/[Zr]). The effect of these reaction parameters on the catalyst activity was investigated using a proposed statistical experimental planning. In the case of f 2 C(Flu)(Cp)ZrCl 2 , SiO 2 and NaM were used as support and the catalyst performance evaluated using toluene and pentane as polymerization solvent. The molecular weight, molecular weight distribution, melting point and crystallinity of the polymers were examined. The results indicate very high activities for the syndiospecific heterogeneous system. Also, the polymers obtained had superior Mw and stereo regularity. (author)

  3. Polypropylene obtained through zeolite supported catalysts

    Directory of Open Access Journals (Sweden)

    Queli C. Bastos

    2004-01-01

    Full Text Available Propylene polymerizations were carried out with f2C(Flu(CpZrCl2 and SiMe2(Ind2ZrCl2 catalysts supported on silica, zeolite sodic mordenite (NaM and acid mordenite (HM. The polymerizations were performed at different temperatures and varying aluminium/zirconium molar ratios ([Al]/[Zr]. The effect of these reaction parameters on the catalyst activity was investigated using a proposed statistical experimental planning. In the case of f2C(Flu(CpZrCl2, SiO2 and NaM were used as support and the catalyst performance evaluated using toluene and pentane as polymerization solvent. The molecular weight, molecular weight distribution, melting point and crystallinity of the polymers were examined. The results indicate very high activities for the syndiospecific heterogeneous system. Also, the polymers obtained had superior Mw and stereoregularity.

  4. Process to Obtain Quick Counts from PREP

    Directory of Open Access Journals (Sweden)

    Martínez–Cruz M.Á.

    2011-10-01

    Full Text Available Considering the Preliminary Electoral Results Program (PERP as a database of the federal elections for president of the Mexican Republic, a methodology was developed in order to find representative samples of ballot boxes installed in the election’s day (quick count in different hours, due to its characteristics of gathering of information, the PREP in the first hours forms a non-representative sample of data. In a particular way, in the election of July 2, 2006, after 3 hours of opening the PREP, it was observed that the accuracy of the process of the quick counts was better than the one obtained by the IFE. Among other things, this allows to lower the cost, to increase the confidentiality of the ballot boxes used in the sampling and to distinguish in a precise moment the winning candidate long before PREP finishes.

  5. Major Depressive Disorder

    Directory of Open Access Journals (Sweden)

    G Grobler

    2013-08-01

    Full Text Available The treatment guideline draws on several international guidelines: (iPractice Guidelines of the American Psychiatric Association (APAfor the Treatment of Patients with Major Depressive Disorder, SecondEdition;[1](ii Clinical Guidelines for the Treatment of DepressiveDisorders by the Canadian Psychiatric Association and the CanadianNetwork for Mood and Anxiety Treatments (CANMAT;[2](iiiNational Institute for Clinical Excellence (NICE guidelines;[3](iv RoyalAustralian and New Zealand College of Psychiatrists Clinical PracticeGuidelines Team for Depression (RANZCAP;[4](v Texas MedicationAlgorithm Project (TMAP Guidelines;[5](vi World Federation ofSocieties of Biological Psychiatry (WFSBP Treatment Guideline forUnipolar Depressive Disorder;[6]and (vii British Association forPsychopharmacology Guidelines.[7

  6. Total magnetic reconnection during a tokamak major disruption

    International Nuclear Information System (INIS)

    Goetz, J.A.

    1990-09-01

    Magnetic reconnection has long been considered to be the cause of sawtooth oscillations and major disruptions in tokamak experiments. Experimental confirmation of reconnection models has been hampered by the difficulty of direct measurement of reconnection, which would involve tracing field lines for many transits around the tokamak. Perhaps the most stringent test of reconnection in a tokamak involves measurement of the safety factor q. Reconnection arising from a single helical disturbance with mode numbers m and n should raise q to m/n everywhere inside of the original resonant surface. Total reconnection should also flatten the temperature and current density profiles inside of this surface. Disruptive instabilities have been studied in the Tokapole 2, a poloidal divertor tokamak. When Tokapole 2 is operated in the material limiter configuration, a major disruption results in current termination as in most tokamaks. However, when operated in the magnetic limiter configuration current termination is suppressed and major disruptions appear as giant sawtooth oscillations. The objective of this thesis is to determine if total reconnection is occurring during major disruptions. To accomplish this goal, the poloidal magnetic field has been directly measured in Tokapole 2 with internal magnetic coils. A full two-dimensional measurement over the central current channel has been done. From these measurements, the poloidal magnetic flux function is obtained and the magnetic surfaces are plotted. The flux-surface-averaged safety factor is obtained by integrating the local magnetic field line pitch over the experimentally obtained magnetic surface

  7. Neurobiology of Major Depressive Disorder

    Directory of Open Access Journals (Sweden)

    Rosa Villanueva

    2013-01-01

    Full Text Available We survey studies which relate abnormal neurogenesis to major depressive disorder. Clinically, descriptive gene and protein expression analysis and genetic and functional studies revised here show that individual alterations of a complex signaling network, which includes the hypothalamic-pituitary-adrenal axis; the production of neurotrophins and growth factors; the expression of miRNAs; the production of proinflammatory cytokines; and, even, the abnormal delivery of gastrointestinal signaling peptides, are able to induce major mood alterations. Furthermore, all of these factors modulate neurogenesis in brain regions involved in MDD, and are functionally interconnected in such a fashion that initial alteration in one of them results in abnormalities in the others. We highlight data of potential diagnostic significance and the relevance of this information to develop new therapeutic approaches. Controversial issues, such as whether neurogenesis is the basis of the disease or whether it is a response induced by antidepressant treatments, are also discussed.

  8. Inequalities theory of majorization and its applications

    CERN Document Server

    Olkin, Ingram

    1980-01-01

    Although they play a fundamental role in nearly all branches of mathematics, inequalities are usually obtained by ad hoc methods rather than as consequences of some underlying ""theory of inequalities."" For certain kinds of inequalities, the notion of majorization leads to such a theory that is sometimes extremely useful and powerful for deriving inequalities. Moreover, the derivation of an inequality by methods of majorization is often very helpful both for providing a deeper understanding and for suggesting natural generalizations.Anyone wishing to employ majorization as a tool in applicati

  9. Rezultatele obţinute în cadrul proiectului AQUACON la analiza apelor de precipitaţii şi a apelor de suprafaţă de către laboratorul I.C.A.S. Câmpulung Moldovenesc [Results obtained in the framework of the AQUACON Project for precipitation and surface water samples by the I.C.A.S. Câmpulung Moldovenesc laboratory

    Directory of Open Access Journals (Sweden)

    Iacoban C

    1999-07-01

    Full Text Available In order to asses the air pollution effects on forests, the laboratories involved in the ICP Forests Program must use analytical methods that allow to obtain comparable results for the precipitation samples parameters (pH, conductivity, alkalinity, SO 4 2-, NO 3 - , NH 4 + , Cl - Ca2+, Mg2+, Na + , K + . In the framework of the project “Analytical Quality Control and Assessment in the Mediterranean Basin (AQUACON”, each year are organized intercomparison exercises using simulated water samples. The chemistry laboratory of the Forest Research Station Campulung Moldovenesc participated to these exercises in 1996, 1997 and 1998. The analytical methods used and the results obtained are presented in this article. It can be concluded that from the total of 110 results ( 10 for each parameter, 8 1 (74 % registered deviations less than 20% and 29 (26 % exceed this limit. The most frequent accepted results (deviation less than 20% were obtained for pH, Na + , conductivity and Mg2+, SO 4 2-, NO 3 - . The lower precisions were obtained for Cl - K + and Ca2+. For K + and Ca2+ we didn’t use the methods recommanded by the Manual ICP Forests and for Cl - we used an alternative method. In order to verify the precision of our methods and results, our laboratory will continue to participate to intercomparison exercises organised by laboratories certificated at European and international level.

  10. Evaluation of pelvic varicose veins using color Doppler ultrasound: comparison of results obtained with ultrasound of the lower limbs, transvaginal ultrasound, and phlebography Avaliação de varizes pélvicas por Doppler colorido: comparação dos resultados obtidos com ultrassom dos membros inferiores, ultrassom transvaginal e flebografia

    Directory of Open Access Journals (Sweden)

    Fanilda Souto Barros

    2010-06-01

    Full Text Available Introduction: Pelvic varicose veins, one of the main causes of chronic pelvic pain and dyspareunia, are an important source of reflux for lower limb varicose veins, especially in recurrent cases. Color Doppler ultrasound of the lower limbs and transvaginal ultrasound are the noninvasive diagnostic methods most commonly used to assess pelvic venous insufficiency, whereas phlebography is still considered as the gold standard. Objectives: To determine the prevalence of lower limb varicose veins originating from the pelvis in a group of female patients and to determine the agreement between results obtained via color Doppler ultrasound of the lower limbs, transvaginal ultrasound, and phlebography. Methods: The sample comprised female patients referred to a vascular laboratory for lower limb screening. Patients diagnosed with deep venous thrombosis were excluded. Data analysis included kappa coefficient of agreement, McNemar's test, sensitivity and specificity values. Results: Of a total of 1,020 patients, 124 (12.2% had findings compatible with reflux of pelvic origin. Among these patients, 51 (41.2% were recurrent cases. A total of 249 were submitted to transvaginal ultrasound. There was significant agreement between lower limb ultrasonographic findings and transvaginal findings. Phlebography was performed in 54 patients. The comparison between transvaginal ultrasound and phlebography was associated with a 96.2% sensitivity and 100% specificity. Conclusions: The authors draw attention to the relatively high prevalence of lower limb varicose veins originating from the pelvis, suggesting an important but underdiagnosed cause of recurrent varicose veins.Introdução: AS VARIZES Pélvicas, uma das principais causas de dor pélvica crônica e dispareunia, são uma importante fonte de refluxo para as varizes dos membros inferiores, especialmente em casos recorrentes. O Doppler colorido dos membros inferiores e o ultrassom transvaginal são os m

  11. Resultados del cabestrillo suburetral transobturatriz con cinta de polipropileno para el tratamiento quirúrgico de la incontinencia de orina de esfuerzo Results obtained with the trans-obturation subureteral sling procedure with polypropylen3 strip for surgical treatment of stress urinary incontinence

    Directory of Open Access Journals (Sweden)

    Radamés Isaac Adefna Pérez

    2011-09-01

    conducted to assess the main demographic variables and the impact on the quality of life and the continence according to the Quality of Life Questionnaire scale for patients presenting with a short urinary incontinence. Results: thirty six patients were operated on with a follow-up of 12 months. The man age is of 51.2 years with predominance of postmenopause and multipara ages. All patients had real or mixed stress incontinence. There was a significant improvement of preoperatory score related to the postoperative one. The yearly success percentage was of 86.1 %. The major complication was the prosthesis erosion and urinary infections. Conclusions: the carrying out of the subureteral sling with prosthesis via trans-obturation that must to be performed in country in patients con stress or mixed urinary incontinence since it is a real and feasible option achieving continence similar to other techniques, with a minor morbidity and a significant economic saving.

  12. Correlations between radiological technology graduates academic achievement and their obtainment of a license

    International Nuclear Information System (INIS)

    Park, Myeong Hwan; Kwon, Deok Moon; Seo, Soo Kyo

    2006-01-01

    The study analyzed the correlations between variables like characteristics related to admission, academic achievement, obtainment of a radiological technology license. A majority of participants were from Daegu and academic high schools. Many participants were accepted by general admission selection, and their reason to apply to Daegu Health College was high graduate employment. Their selection for the academic program was made by their parents and themselves. Those who took the same course twice held 35.1%, and those who got an academic warning took 8.5%. The degree of participants' academic achievement showed somewhat low, and they had difficulty in taking their major courses. The average grade for admission was lower in a following selection order: college graduates, general, special, and rural areas. The admission selections and taking science courses in high school showed little significant correlations with obtainment of a radiological technology license. However, the obtainment of the license had significant correlations with retaking the same course, getting an academic warning, and the degree of academic achievement. The results also revealed that the obtainment of the license had little significant correlations with a part-time job experience, having a boy/girlfriend, and student club participation, but it had significant correlations with accommodations and study club participation. In conclusion, it is important to point out that radiological technology graduates' obtainment of a license is closely related with the degree of their academic achievement and their college life

  13. Obtaining of potassium dicyan-argentate

    International Nuclear Information System (INIS)

    Sattarova, M.A.; Solojenkin, P.M.

    1997-01-01

    This work is devoted to obtaining of potassium dicyan-argentate. By means of exchange reaction between silver nitrate and potassium cyanide the potassium dicyan-argentate was synthesized. The analysis of obtained samples was carried out by means of titration and potentiometry.

  14. Treating shale oil to obtain sulfonates

    Energy Technology Data Exchange (ETDEWEB)

    Schaeffer, H

    1921-01-21

    The process shows as its principal characteristics: (1) treating the oil with chlorsulfonic acid at a temperature of about 100/sup 0/C; (2) the transformation of the sulfonic acid obtained into salts; (3) as new industrial products, the sulfonates obtained and their industrial application as disinfectants for hides and wood.

  15. Strategies for obtaining unpublished drug trial data

    DEFF Research Database (Denmark)

    Wolfe, Nicole; Gøtzsche, Peter C.; Bero, Lisa Anne

    2013-01-01

    Authors of systematic reviews have difficulty obtaining unpublished data for their reviews. This project aimed to provide an in-depth description of the experiences of authors in searching for and gaining access to unpublished data for their systematic reviews, and to give guidance on best...... practices for identifying, obtaining and using unpublished data....

  16. 38 CFR 21.5725 - Obtaining benefits.

    Science.gov (United States)

    2010-07-01

    ... 38 Pensions, Bonuses, and Veterans' Relief 2 2010-07-01 2010-07-01 false Obtaining benefits. 21... benefits. (a) Actions required of the individual. In order to obtain benefits under the educational assistance and subsistence allowance program, an individual must— (1) File a claim for benefits with VA, and...

  17. Shielding design to obtain compact marine reactor

    International Nuclear Information System (INIS)

    Yamaji, Akio; Sako, Kiyoshi

    1994-01-01

    The marine reactors equipped in previously constructed nuclear ships are in need of the secondary shield which is installed outside the containment vessel. Most of the weight and volume of the reactor plants are occupied by this secondary shield. An advanced marine reactor called MRX (Marine Reactor X) has been designed to obtain a more compact and lightweight marine reactor with enhanced safety. The MRX is a new type of marine reactor which is an integral PWR (The steam generator is installed in the pressure vessel.) with adopting a water-filled containment vessel and a new shielding design method of no installation of the secondary shield. As a result, MRX is considerably lighter in weight and more compact in size as compared with the reactors equipped in previously constructed nuclear ships. For instance, the plant weight and volume of the containment vessel of MRX are about 50% and 70% of those of the Nuclear Ship MUTSU, in spite of the power of MRX is 2.8 times as large as the MUTSU's reactor. The shielding design calculation was made using the ANISN, DOT3.5, QAD-CGGP2 and ORIGEN codes. The computational accuracy was confirmed by experimental analyses. (author)

  18. Reduced sensitivity RDX obtained from bachmann RDX

    Energy Technology Data Exchange (ETDEWEB)

    Spyckerelle, Christian; Eck, Genevieve [EURENCO France, Sorgues Plant 1928 route d' Avignon, BP 311, 84706 Sorgues Cedex (France); Sjoeberg, Per; Amneus, Anna-Maria [EURENCO Sweden, SE-69186 Karlskoga (Sweden)

    2008-02-15

    In recent years much interest has been generated in a quality of reduced sensitivity RDX (RS-RDX), like I-RDX {sup registered} which, when incorporated in cast cure and even pressable plastic bonded explosives (PBX compositions), can confer reduced shock sensitivity as measured through gap test. At crystal level, lot of work has been done to try to determine which property or properties may explain the behaviour of the corresponding cast PBX composition. But up to now, and despite an international inter-laboratory comparison (Round Robin) of seven lots of RDX from five different manufacturers conducted from 2003 to 2005, even if some techniques lead to interesting results, there is no dedicated specification to apply to RS-RDX. This quality (I-RDX {sup registered}) has proved to retain its low sensitivity even after ageing, which does not seem to be the case for standard RDX produced by the Bachmann process (when re-crystallized under I-RDX conditions in order to obtain RS-RDX). It has been shown that the higher sensitivity of RDX produced by the Bachmann process, or the evolution of sensitivity after ageing of RS-RDX produced from Bachmann RDX may be linked to the presence of octogen (HMX) during the crystallization process. In order to check such hypothesis, low HMX content RDX produced by the Bachmann process has been prepared and evaluated in cast PBX composition (PBX N 109). Results of the characterization of such quality of RDX and its evaluation in cast PBX composition as well as ageing behaviour are presented and discussed; there are indications that removal of HMX from Bachmann RDX may lead to RS-RDX, which retains its RS character even after ageing. (Abstract Copyright [2008], Wiley Periodicals, Inc.)

  19. Alterations of Regional Cerebral Blood Flow in Major Depressive Disorder

    Energy Technology Data Exchange (ETDEWEB)

    Lee, Won Hyoung; Chung, Yong An; Seo, Ye Young; Yoo, Ik Dong; Na, Sae Jung; Jung, Hyun Suk; Kim, Ki Jun [College of Medicine, The Catholic University of Korea, Seoul (Korea, Republic of)

    2009-04-15

    The authors analyzed how the regional cerebral blood flow (rCBF) findings of patients with major depression differ from the normal control, and our results were compared to previous reports. Twelve patients fulfilling DSM-IV criteria for major depression who were off all psychotropic medications for > 4 weeks (male: 7, female: 5, age range: 19approx52 years, average age: 29.3+-9.9 years) and 14 normal volunteers (male: 8, female: 6, age range: 19approx53 years, average age: 31.4+-9.2 years) were recruited. Images of brain perfusion SPECT were obtained using Tc-99m ECD and patterns of the rCBF were compared between patients with major depression and the healthy control subjects. The patients with major depression showed increase of the r-CBF in right lingual gyrus, right fusiform gyrus, left lingual gyrus, left precuneus, and left superior temporal gyrus, and showed decrease of r-CBF in right pons, left medial frontal gyrus, cingulate gyrus of left limbic lobe, cingulate gyrus of right frontal lobe, and cingulate gyrus of right limbic lobe compared to the normal control. The Tc-99m ECD brain perfusion SPECT findings in our study did not differ from the previously reported regional cerebral blood flow pattern of patients with major depression. Especially, decreased rCBF pattern typical to major depression patients in the right pons, left medial frontal gyrus, and cingulate regions was clearly demonstrated

  20. Alterations of Regional Cerebral Blood Flow in Major Depressive Disorder

    International Nuclear Information System (INIS)

    Lee, Won Hyoung; Chung, Yong An; Seo, Ye Young; Yoo, Ik Dong; Na, Sae Jung; Jung, Hyun Suk; Kim, Ki Jun

    2009-01-01

    The authors analyzed how the regional cerebral blood flow (rCBF) findings of patients with major depression differ from the normal control, and our results were compared to previous reports. Twelve patients fulfilling DSM-IV criteria for major depression who were off all psychotropic medications for > 4 weeks (male: 7, female: 5, age range: 19∼52 years, average age: 29.3±9.9 years) and 14 normal volunteers (male: 8, female: 6, age range: 19∼53 years, average age: 31.4±9.2 years) were recruited. Images of brain perfusion SPECT were obtained using Tc-99m ECD and patterns of the rCBF were compared between patients with major depression and the healthy control subjects. The patients with major depression showed increase of the r-CBF in right lingual gyrus, right fusiform gyrus, left lingual gyrus, left precuneus, and left superior temporal gyrus, and showed decrease of r-CBF in right pons, left medial frontal gyrus, cingulate gyrus of left limbic lobe, cingulate gyrus of right frontal lobe, and cingulate gyrus of right limbic lobe compared to the normal control. The Tc-99m ECD brain perfusion SPECT findings in our study did not differ from the previously reported regional cerebral blood flow pattern of patients with major depression. Especially, decreased rCBF pattern typical to major depression patients in the right pons, left medial frontal gyrus, and cingulate regions was clearly demonstrated

  1. To report the obtained results in the operation multicycle study of the L V U-1 using design data with the FCSII (1D) and PRESTO (3D) codes of the FMS system; Reportar los resultados obtenidos en el estudio de multiciclos de operacion de LV U-1 utilizando datos de diseno con los codigos FCSII (1D) y PRESTO (3D) del sistema FMS

    Energy Technology Data Exchange (ETDEWEB)

    Montes T, J L; Cortes C, C C

    1991-07-15

    This work is to carry out a multicycle study for the Laguna Verde U-1 reactor with the FCS-II (1 - 20 cycles) and PRESTO (1 - 6 cycles) codes and to compare the obtained results against those reported by General Electric. (Author)

  2. Aberrant thermoluminescence dates obtained from primary volcanic quartz

    International Nuclear Information System (INIS)

    Guerin, Gilles; Samper, Agnes

    2007-01-01

    This study deals with the dating by thermoluminescence (TL) of quartz from six volcanic formations of the Saint Lucia Island (Lesser Antilles Arc). Quartz microcrystals up to one millimetre in size were extracted from dacites and pumice flows and prepared in a way similar to the well-known inclusion technique. The TL properties of these quartz were used to estimate apparent palaeodoses using the multi-aliquot protocol. The quartz TL was studied in three different spectral domains: red, green and ultraviolet/blue. The calculated annual dose-rates yielded a set of 18 age-estimates. For some samples complementary dates were obtained using high temperature TL (HTTL) of plagioclase feldspars. These latter dates combined with previously determined radiocarbon and unspiked K-Ar dates were used to explore the validity of ages computed from the TL of quartz. Individual values for quartz appear to be scattered and do not match ages deduced from 14 C, unspiked K-Ar or HTTL on plagioclase dates. These results indicate that when conventional TL methodologies derived from the inclusion method are applied to volcanic quartz major dating problems are to be expected

  3. Aberrant thermoluminescence dates obtained from primary volcanic quartz

    Energy Technology Data Exchange (ETDEWEB)

    Guerin, Gilles [Laboratoire des Sciences du Climat et de l' Environnement, CEA-CNRS, avenue de la Terrasse, 91191 Gif-sur-Yvette (France)], E-mail: gilles.guerin@u-psud.fr; Samper, Agnes [Laboratoire de geochronologie multitechnique (UPS-IPGP), Universite de Paris-Sud Orsay, 91405 Orsay Cedex (France)

    2007-10-15

    This study deals with the dating by thermoluminescence (TL) of quartz from six volcanic formations of the Saint Lucia Island (Lesser Antilles Arc). Quartz microcrystals up to one millimetre in size were extracted from dacites and pumice flows and prepared in a way similar to the well-known inclusion technique. The TL properties of these quartz were used to estimate apparent palaeodoses using the multi-aliquot protocol. The quartz TL was studied in three different spectral domains: red, green and ultraviolet/blue. The calculated annual dose-rates yielded a set of 18 age-estimates. For some samples complementary dates were obtained using high temperature TL (HTTL) of plagioclase feldspars. These latter dates combined with previously determined radiocarbon and unspiked K-Ar dates were used to explore the validity of ages computed from the TL of quartz. Individual values for quartz appear to be scattered and do not match ages deduced from {sup 14}C, unspiked K-Ar or HTTL on plagioclase dates. These results indicate that when conventional TL methodologies derived from the inclusion method are applied to volcanic quartz major dating problems are to be expected.

  4. The Prototypical Majority Effect Under Social Influence.

    Science.gov (United States)

    Koriat, Asher; Adiv-Mashinsky, Shiri; Undorf, Monika; Schwarz, Norbert

    2018-05-01

    Majority views are reported with greater confidence and fluency than minority views, with the difference increasing with majority size. This Prototypical Majority Effect (PME) was attributed generally to conformity pressure, but Koriat et al. showed that it can arise from the processes underlying decision and confidence independent of social influence. Here we examined the PME under conditions that differ in social influence. In Experiment 1, a robust PME emerged in the absence of information about the majority views, but the provision sof that information increased the choice of the majority view and magnified the PME. In Experiment 2, a PME emerged in a minority-biased condition that misled participants to believe that the majority view was the minority view, but the PME was stronger in a majority-biased condition. The results were discussed in terms of a dual-process view: The PME observed under social influence may contain externally driven and internally driven components.

  5. Utilização da densitometria óssea como método de avaliação dos resultados da utilização de BMP bovina em artrodese de coluna em coelhos Bone densitometry in the evaluation of the results obtained with the use of bovine BMP in spine arthrodesis in rabbits

    Directory of Open Access Journals (Sweden)

    Paulo Roberto Moura Machado

    2005-01-01

    do osso normal nos dois grupos.The object of this study is to evaluate the use of the bone densitometry as an evaluation method of the bone increment observed when we used bovine BMP in intertransverse arthrodesis of the rabbits' lumbar spine. Since the discovery of the BMP bone inductive properties, countless experimental models have been proposed. This caused the need of setting up evaluation methods to make possible a better understanding of the found results. Twenty female rabbits from New Zealand, divided in two groups, were submitted to the intertransverse arthrodesis of the lumbar column, segment L5/L6, posterior side. In the first group it was used autologous graft and in the second an association of autologous graft with biocompound (bovine BMP, 1.0 mg and hydroxyapatite, 9.0 mg. The animals were maintained in captivity, isolated and after 15 weeks submitted to the execution of bone densitometry by computerized tomography. 268 bone density measures of the normal bone, 134 measures of the newly formed bone by the association of the isolated autologous graft and 134 measures of the newly formed bone by the association autologous graft and BMP were obtained, what demonstrated a significant bone increment after statistical analysis (p=0.034 of the BMP/HAP group, when compared to the control group. We found this same variation of bone density analyzing the normal bone. The bone densitometry accomplished by the computerized tomography is an alternative method to assess the results when the BMP is used in experimental studies. Further studies should be accomplished for better understanding of the bone density variation found when the measures of the normal bone in the two groups are compared.

  6. Production and characterization of pectinases obtained from ...

    African Journals Online (AJOL)

    Production and characterization of pectinases obtained from Aspergillus fumigatus in submerged fermentation system using pectin extracted from mango peels as carbon source. AL Ezugwu, SOO Eze, FC Chilaka, CU Anyanwu ...

  7. Treatment of biomass to obtain ethanol

    Science.gov (United States)

    Dunson, Jr., James B.; Elander, Richard T [Evergreen, CO; Tucker, III, Melvin P.; Hennessey, Susan Marie [Avondale, PA

    2011-08-16

    Ethanol was produced using biocatalysts that are able to ferment sugars derived from treated biomass. Sugars were obtained by pretreating biomass under conditions of high solids and low ammonia concentration, followed by saccharification.

  8. Silicon dioxide obtained by Polymeric Precursor Method

    International Nuclear Information System (INIS)

    Oliveira, C.T.; Granado, S.R.; Lopes, S.A.; Cavalheiro, A.A.

    2011-01-01

    The Polymeric Precursor Method is able for obtaining several oxide material types with high surface area even obtained in particle form. Several MO 2 oxide types such as titanium, silicon and zirconium ones can be obtained by this methodology. In this work, the synthesis of silicon oxide was monitored by thermal analysis, XRD and surface area analysis in order to demonstrate the influence of the several synthesis and calcining parameters. Surface area values as higher as 370m2/g and increasing in the micropore volume nm were obtained when the material was synthesized by using ethylene glycol as polymerizing agent. XRD analysis showed that the material is amorphous when calcinated at 600°C in despite of the time of calcining, but the material morphology is strongly influenced by the polymeric resin composition. Using Glycerol as polymerizing agent, the pore size increase and the surface area goes down with the increasing in decomposition time, when compared to ethylene glycol. (author)

  9. Metagenomics as a tool to obtain full genomes of process-critical bacteria in engineered systems

    DEFF Research Database (Denmark)

    Albertsen, Mads; Hugenholtz, Philip; Tyson, Gene W.

    of the community. The assembled genomes include many of the process-critical bacteria involved in wastewater treatment, such as Competibacter, Tetrasphaera and TM7. The approach is not limited to different extraction methods, but can be applied to any treatment that results in different relative abundance......Bacteria play a pivotal role in engineered systems such as wastewater treatment plants. Obtaining genomes of the bacteria provides the genetic potential of the system and also allows studies of in situ functions through transcriptomics and proteomics. Hence, it enables correlations of operational......, the sequencing of bulk genomic DNA from environmental samples, has the potential to provide genomes of this uncultured majority. However, so far only few bacterial genomes have been obtained from metagenomic data. In this study we present a new approach to obtain individual genomes from metagenomes. We deeply...

  10. Component Repair Times Obtained from MSPI Data

    International Nuclear Information System (INIS)

    Eide, Steven A.; Cadwallader, Lee

    2015-01-01

    Information concerning times to repair or restore equipment to service given a failure is valuable to probabilistic risk assessments (PRAs). Examples of such uses in modern PRAs include estimation of the probability of failing to restore a failed component within a specified time period (typically tied to recovering a mitigating system before core damage occurs at nuclear power plants) and the determination of mission times for support system initiating event (SSIE) fault tree models. Information on equipment repair or restoration times applicable to PRA modeling is limited and dated for U.S. commercial nuclear power plants. However, the Mitigating Systems Performance Index (MSPI) program covering all U.S. commercial nuclear power plants provides up-to-date information on restoration times for a limited set of component types. This paper describes the MSPI program data available and analyzes the data to obtain median and mean component restoration times as well as non-restoration cumulative probability curves. The MSPI program provides guidance for monitoring both planned and unplanned outages of trains of selected mitigating systems deemed important to safety. For systems included within the MSPI program, plants monitor both train UA and component unreliability (UR) against baseline values. If the combined system UA and UR increases sufficiently above established baseline results (converted to an estimated change in core damage frequency or CDF), a ''white'' (or worse) indicator is generated for that system. That in turn results in increased oversight by the US Nuclear Regulatory Commission (NRC) and can impact a plant's insurance rating. Therefore, there is pressure to return MSPI program components to service as soon as possible after a failure occurs. Three sets of unplanned outages might be used to determine the component repair durations desired in this article: all unplanned outages for the train type that includes the component of

  11. Component Repair Times Obtained from MSPI Data

    Energy Technology Data Exchange (ETDEWEB)

    Eide, Steven A. [Curtiss-Wright/Scietech, Ketchum, ID (United States); Cadwallader, Lee [Idaho National Lab. (INL), Idaho Falls, ID (United States)

    2015-05-01

    Information concerning times to repair or restore equipment to service given a failure is valuable to probabilistic risk assessments (PRAs). Examples of such uses in modern PRAs include estimation of the probability of failing to restore a failed component within a specified time period (typically tied to recovering a mitigating system before core damage occurs at nuclear power plants) and the determination of mission times for support system initiating event (SSIE) fault tree models. Information on equipment repair or restoration times applicable to PRA modeling is limited and dated for U.S. commercial nuclear power plants. However, the Mitigating Systems Performance Index (MSPI) program covering all U.S. commercial nuclear power plants provides up-to-date information on restoration times for a limited set of component types. This paper describes the MSPI program data available and analyzes the data to obtain median and mean component restoration times as well as non-restoration cumulative probability curves. The MSPI program provides guidance for monitoring both planned and unplanned outages of trains of selected mitigating systems deemed important to safety. For systems included within the MSPI program, plants monitor both train UA and component unreliability (UR) against baseline values. If the combined system UA and UR increases sufficiently above established baseline results (converted to an estimated change in core damage frequency or CDF), a “white” (or worse) indicator is generated for that system. That in turn results in increased oversight by the US Nuclear Regulatory Commission (NRC) and can impact a plant’s insurance rating. Therefore, there is pressure to return MSPI program components to service as soon as possible after a failure occurs. Three sets of unplanned outages might be used to determine the component repair durations desired in this article: all unplanned outages for the train type that includes the component of interest, only

  12. Análise invasiva e não invasiva do fuso meiótico de oócitos humanos obtidos de ciclos estimulados: dados preliminares Invasive and noninvasive analysis of the meiotic spindle of human oocytes obtained from stimulate cycles: preliminary results

    Directory of Open Access Journals (Sweden)

    Luciana Azôr Dib

    2012-11-01

    preditivo de normalidade meiótica oocitária.PURPOSE: To evaluate the concordance between polarization microscopy and confocal microscopy techniques in the evaluation of the meiotic spindle of human oocytes matured in vivo. METHODS: Prospective study that evaluated oocytes with the first polar extruded body obtained from infertile women who had undergone ovarian stimulation for intracytoplasmic sperm injection. The oocytes with the first polar extruded body were evaluated by polarization microscopy and were then immediately fixed and stained for microtubule and chromatin evaluation by high-performance confocal microscopy. We determined the correlation of polarization microscopy with confocal microscopy in the detection of meiotic oocyte anomalies, and we also evaluated the percentage of oocytes with a visible and non-visible cell spindle by polarization microscopy and with meiotic normality and abnormalities by confocal microscopy. Confidence intervals, Kappa's index and concordance between the methodologies were calculated, considering immunofluorescence microscopy analysis as the golden-standard for evaluating normal spindle and oocyte chromosome distribution. RESULTS: We observed that 72.7% of metaphase II oocytes with a nonvisible meiotic spindle by polarization microscopy showed no meiotic abnormalities by confocal analysis and 55.6% of metaphase II oocytes with a visible meiotic spindle by polarization microscopy were found to be abnormal oocytes by the confocal analysis. Only 44.4% of oocytes with a visible meiotic spindle by polarization microscopy were found to be normal by confocal analysis. Concordance between the methods was 51.1% (Kappa: 0.11; 95%CI -0.0958 - 0.319. CONCLUSIONS: The low correlation between polarization microscopy and confocal microscopy in the assessment of oocyte meiotic spindle suggests that visualization of the meiotic spindle of human oocytes at metaphase II by polarization microscopy is not a good indicator of oocyte meiotic normality.

  13. Thermal Radiation Anomalies Associated with Major Earthquakes

    Science.gov (United States)

    Ouzounov, Dimitar; Pulinets, Sergey; Kafatos, Menas C.; Taylor, Patrick

    2017-01-01

    Recent developments of remote sensing methods for Earth satellite data analysis contribute to our understanding of earthquake related thermal anomalies. It was realized that the thermal heat fluxes over areas of earthquake preparation is a result of air ionization by radon (and other gases) and consequent water vapor condensation on newly formed ions. Latent heat (LH) is released as a result of this process and leads to the formation of local thermal radiation anomalies (TRA) known as OLR (outgoing Longwave radiation, Ouzounov et al, 2007). We compare the LH energy, obtained by integrating surface latent heat flux (SLHF) over the area and time with released energies associated with these events. Extended studies of the TRA using the data from the most recent major earthquakes allowed establishing the main morphological features. It was also established that the TRA are the part of more complex chain of the short-term pre-earthquake generation, which is explained within the framework of a lithosphere-atmosphere coupling processes.

  14. A Major in Science? Initial Beliefs and Final Outcomes for College Major and Dropout

    OpenAIRE

    Ralph Stinebrickner; Todd R. Stinebrickner

    2014-01-01

    Taking advantage of unique longitudinal data, we provide the first characterization of what college students believe at the time of entrance about their final major, relate these beliefs to actual major outcomes, and provide an understanding of why students hold the initial beliefs about majors that they do. The data collection and analysis are based directly on a conceptual model in which a student's final major is best viewed as the end result of a learning process. We find that students en...

  15. Obtain of uranium concentrates from fertil liquids

    International Nuclear Information System (INIS)

    Narvaez Castillo, W.A.

    1992-01-01

    This research tried to encounter the form to remove uranium from the rock in the best way, for that it was used different process like leaching, extraction, concentration and precipitation. To leach the mineral was chosen basic leaching, using a mixture of carbonate-sodium bicarbonate, this method is more adequated for the basic nature of the mineral. In extraction was used specific uranium ionic interchanges, so was chosen a tertiary amine like Alamina 336. The concentration phase is intimately binding with the extraction by ionic interchange, for the capability of resine's extraction to obtain concentrated liquids. When the liquids were obtained with high concentration of uranium in the same time were purified and then were precipitated, for that we employed a precipitant agent like: Sodium hydroxide, Amonium hydroxide, Magnesium hydroxide, Hydrogen peroxide and phosphates. With all concentrates we obtain the YELLOW CAKE

  16. [Molecular characterization of Echinococcus granulosus isolates obtained from different hosts].

    Science.gov (United States)

    Erdoğan, Emrah; Özkan, Bora; Mutlu, Fatih; Karaca, Serkan; Şahin, İzzet

    2017-01-01

    Echinococcus granulosus is a parasite that can be seen throughout the world. So far, five species of genus Echinococcus have been identified as parasite in people: E.granulosus, E.multilocularis, E.vogeli, E.oligarthrus, E.shiquicus. Larval (metacestod) form of parasite settles in internal organs of hoofed animals (cattle, goats, pigs, horses, sheep, etc.) and human; the adult form is found in small intestine of final host, canine. Disease caused by parasite called as "Cystic echinococcosis" (CE) is an important health problem and causes economic losses in many countries including our country that livestock is common. Infective eggs cause infections in intermediate hosts by taking oral way and rarely inhalation. Received egg opens in the stomach and intestines of intermediate host and oncosphere is released. Oncosphere quickly reaches the lamina propria of the villus epithelium by its histolytic enzymes and hooks. It usually transported from here to the liver and lungs, less frequently, muscle, brain, spleen, kidney and to other organs through the veins. By molecular studies, five species have been validated taxonomically and 10 different variants or strains of E.granulosus have been identified. Host and developmental differences between strains may negatively affect control studies and fight against the parasite. This study aimed to determinate E.granulosus strains obtained from cyst material of different intermediate hosts from different regions of Turkey by molecular methods. In the study, 25 human, 8 cattle, 6 sheep and 2 goat cysts material has been collected. Total genomic DNA was isolated from protoscoleces in cyst fluid and analyzed by PCR with COX-1 (L) and COX-1 (S) genes specific primers. DNA sequence analysis for each PCR product has been made. DNA sequence analysis results evaluated phylogenetically by MEGA analyze and BLAST software. As a result of this study, all isolates were identified as E.granulosus sensu stricto (G1) by DNA sequence analysis. CE

  17. Weaving History through the Major

    Science.gov (United States)

    Mayfield, Betty

    2014-01-01

    The benefits of including the study of the history of mathematics in the education of mathematics majors have been discussed at length elsewhere. Many colleges and universities now offer a History of Mathematics course for mathematics majors, for mathematics education majors, or for general credit. At Hood College, we emphasize our commitment to…

  18. Obtaining the Andersen's chart, triangulation algorithm

    DEFF Research Database (Denmark)

    Sabaliauskas, Tomas; Ibsen, Lars Bo

    Andersen’s chart (Andersen & Berre, 1999) is a graphical method of observing cyclic soil response. It allows observing soil response to various stress amplitudes that can lead to liquefaction, excess plastic deformation or stabilizing soil response. The process of obtaining the original chart has...

  19. Obtaining shale distillate free from sulphur

    Energy Technology Data Exchange (ETDEWEB)

    Heyl, G E

    1917-09-14

    A process whereby, from sulfur-containing shale, products free from sulfur may be obtained, consisting of mixing with the finely ground shale a portion of iron salts containing sufficient metal to unite with all the sulfur in the shale and form sulfide therewith, grinding the mixture to a fine state of subdivision and subsequently subjecting it to destructive distillation.

  20. Obtaining a minimal set of rewrite rules

    CSIR Research Space (South Africa)

    Davel, M

    2005-11-01

    Full Text Available In this paper the authors describe a new approach to rewrite rule extraction and analysis, using Minimal Representation Graphs. This approach provides a mechanism for obtaining the smallest possible rule set – within a context-dependent rewrite rule...

  1. Isolation and characterization of microcrystalline cellulose obtained ...

    African Journals Online (AJOL)

    In this study, microcrystalline cellulose, coded MCC-PNF, was obtained from palm nut (Elaeis guineensis) fibres. MCC-PNF was examined for its physicochemical and powder properties. The powder properties of MCC-PNF were compared to those of the best commercial microcrystalline cellulose grade, Avicel PH 101.

  2. 47 CFR 54.615 - Obtaining services.

    Science.gov (United States)

    2010-10-01

    ... provided under § 54.621, that the requester cannot obtain toll-free access to an Internet service provider... thing of value; (6) If the service or services are being purchased as part of an aggregated purchase... submitted and select the most cost-effective alternative. (b) Receiving supported rate. Except with regard...

  3. Do Biology Majors Really Differ from Non–STEM Majors?

    Science.gov (United States)

    Cotner, Sehoya; Thompson, Seth; Wright, Robin

    2017-01-01

    Recent calls to action urge sweeping reform in science education, advocating for improved learning for all students—including those majoring in fields beyond the sciences. However, little work has been done to characterize the differences—if any exist—between students planning a career in science and those studying other disciplines. We describe an attempt to clarify, in broad terms, how non–STEM (science, technology, engineering, and mathematics) majors differ from life sciences majors, and how they are similar. Using survey responses and institutional data, we find that non–STEM majors are not unilaterally science averse; non–STEM majors are more likely than biology majors to hold misconceptions about the nature of science, yet they are not completely ignorant of how science works; non–STEM majors are less likely than biology majors to see science as personally relevant; and non–STEM majors populations are likely to be more diverse—with respect to incoming knowledge, perceptions, backgrounds, and skills—than a biology majors population. We encourage science educators to consider these characteristics when designing curricula for future scientists or simply for a well-informed citizenry. PMID:28798210

  4. Mathematical models for correction of images, obtained at radioisotope scan

    International Nuclear Information System (INIS)

    Glaz, A.; Lubans, A.

    2002-01-01

    The images, which obtained at radioisotope scintigraphy, contain distortions. Distortions appear as a result of absorption of radiation by patient's body's tissues. Two mathematical models for reducing of such distortions are proposed. Image obtained by only one gamma camera is used in the first mathematical model. Unfortunately, this model allows processing of the images only in case, when it can be assumed, that the investigated organ has a symmetric form. The images obtained by two gamma cameras are used in the second model. It gives possibility to assume that the investigated organ has non-symmetric form and to acquire more precise results. (authors)

  5. The ion-exchange obtaining of high purity samarium oxide

    International Nuclear Information System (INIS)

    Brzyska, W.; Soltysiak, I.; Cygan, J.

    1987-01-01

    The use of lactic acid - EDTA mixture as an eluent for the obtaining of high purity samarium oxide was studied. The studies were carried out at room temperature on cation exchange resin Wofatit KPS X 8. The best results were obtained for lactic acid (0,26 mol/dm 3 ) - EDTA (0,013 mol/dm 3 ) mixture at pH 3,3. As the result of 57% samarium concentrate elution with column load 1:3 and flow rate 0,4 cm/min, over 99% pure samarium oxide with 73% yield has been obtained. The yield of spectrally pure Sm 2 O 3 exceeded 45%. (author)

  6. Major Environmental Policy in 2000

    Energy Technology Data Exchange (ETDEWEB)

    Choi, Hong Jin [Ministry Of Environment, Kwachon (Korea)

    2000-04-01

    As a new millennium has started, there are active movements developing a basic paradigm of vision and policy over a nation-wide to prepare changes actively. For the environmental sector, it is possible to live in a pleasant environment if everyone prepare and work together like dealing with Y2K problem. With a goal of being an environmentally advanced country in the early new millennium, it is planned to improve a basic life environment such as water and air and to promote an advanced environmental management policy for showing results of its reform in 2000. Therefore, it examines environmental management circumstances and a direction of environmental policy first and it discusses more about major environmental policy related to petroleum industry. 7 tabs.

  7. Superconductive ceramics obtained with sol gel method

    International Nuclear Information System (INIS)

    Arcangeli, A.; Mosci, A.; Nardi, A.; Vatteroni, R.; Zondini, C.

    1988-01-01

    Several sol gel routes have been considered, studied and developed to produce large quantities of granulates which can be processed to obtain ceramics having good superconducting characteristics. In the considered process a mixture of commercial nitrates is atomized, at room temperature, in a solution 1:1 of Primene JMT and Benzene and a pale blue gel of the starting elements is suddently formed. The granulates obtained are free flowing, very reactive and well suited for pressing. For their intrinsic characteristics they could be very good precursors for the production of large quantities of superconductive ceramics in different forms. The precipitated gel is dried, calcinated, pressed in the form of cylindrical pellets which are sintered up to 960 degrees C. No griding or different thermal treatments are needed. The sintered material has low electric resistence, shows a clear Meissner effect and has a transition temperature of between 91 and 95 K

  8. Acoustic barriers obtained from industrial wastes.

    Science.gov (United States)

    Garcia-Valles, M; Avila, G; Martinez, S; Terradas, R; Nogués, J M

    2008-07-01

    Acoustic pollution is an environmental problem that is becoming increasingly more important in our society. Likewise, the accumulation of generated waste and the need for waste management are also becoming more and more pressing. In this study we describe a new material--called PROUSO--obtained from industrial wastes. PROUSO has a variety of commercial and engineering, as well as building, applications. The main raw materials used for this environmentally friendly material come from slag from the aluminium recycling process, dust from the marble industry, foundry sands, and recycled expanded polystyrene from recycled packaging. Some natural materials, such as plastic clays, are also used. To obtain PROUSO we used a conventional ceramic process, forming new mineral phases and incorporating polluted elements into the structure. Its physical properties make PROUSO an excellent acoustic and thermal insulation material. It absorbs 95% of the sound in the frequency band of the 500 Hz. Its compressive strength makes it ideal for use in ceramic wall building.

  9. Processing of hydroxyapatite obtained by combustion synthesis

    International Nuclear Information System (INIS)

    Canillas, M.; Rivero, R.; García-Carrodeguas, R.; Barba, F.; Rodríguez, M.A.

    2017-01-01

    One of the reasons of implants failure are the stress forces appearing in the material–tissue interface due to the differences between their mechanical properties. For this reason, similar mechanical properties to the surrounding tissue are desirable. The synthesis of hydroxyapatite by solution combustion method and its processing have been studied in order to obtain fully dense ceramic bodies with improved mechanical strength. Combustion synthesis provides nanostructured powders characterized by a high surface area to facilitate the following sintering. Moreover, synthesis was conducted in aqueous and oxidizing media. Oxidizing media improve homogenization and increase the energy released during combustion. It gives rise to particles whose morphology and size suggest lower surface energies compared with aqueous media. The obtained powders were sintered by using a controlled sintering rate schedule. Lower surfaces energies minimize the shrinkage during sintering and relative densities measurements and diametral compression test confirm improved densification and consequently mechanical properties. [es

  10. Process for obtaining luminescent glass layers

    International Nuclear Information System (INIS)

    Heindi, R.; Robert, A.

    1984-01-01

    Process for obtaining luminescent glass layers, application to the production of devices provided with said layers and to the construction of photoscintillators. The process comprises projecting onto a support, by cathodic sputtering, the material of at least one target, each target including silica and at least one chemical compound able to give luminescent centers, such as a cerium oxide, so as to form at least one luminescent glass layer of the said support. The layer or layers formed preferably undergo a heat treatment such as annealing in order to increase the luminous efficiency thereof. It is in this way possible to form a scintillating glass layer on the previously frosted entrance window of a photomultiplier in order to obtain an integrated photoscintillator

  11. Processing of hydroxyapatite obtained by combustion synthesis

    Directory of Open Access Journals (Sweden)

    M. Canillas

    2017-09-01

    Full Text Available One of the reasons of implants failure are the stress forces appearing in the material–tissue interface due to the differences between their mechanical properties. For this reason, similar mechanical properties to the surrounding tissue are desirable. The synthesis of hydroxyapatite by solution combustion method and its processing have been studied in order to obtain fully dense ceramic bodies with improved mechanical strength. Combustion synthesis provides nanostructured powders characterized by a high surface area to facilitate the following sintering. Moreover, synthesis was conducted in aqueous and oxidizing media. Oxidizing media improve homogenization and increase the energy released during combustion. It gives rise to particles whose morphology and size suggest lower surface energies compared with aqueous media. The obtained powders were sintered by using a controlled sintering rate schedule. Lower surfaces energies minimize the shrinkage during sintering and relative densities measurements and diametral compression test confirm improved densification and consequently mechanical properties.

  12. Trochleoplasty in major trochlear dysplasia: current concepts

    Directory of Open Access Journals (Sweden)

    Beaufils Philippe

    2012-02-01

    Full Text Available Abstract Trochleoplasty is the theoretical solution to persistent symptoms (pain and/or instability related to trochlear dysplasia where there is not only a trochlear flatness but also a trochlear prominence. The threshold of prominence indicating surgical intervention has as yet not been determined. A bump of 5 mm is generally accepted as the inferior limit. Given the interventional nature of this demanding procedure, it should be proposed in selected cases after considerable discussion with the patient. Trochleoplasty is indicated as a primary procedure for major trochlear dysplasia with a prominence > 5 mm. Stabilization is obtained in most of the cases with the risk of residual mild anterior knee pain. It is also indicated as a salvage procedure when a previous surgery failed. Despite the reputation of the procedure, the published results are encouraging in terms of prevention of re-dislocation, satisfaction index, and radiological outcomes. Post-operative stiffness is the main complication, which may require manipulation under anaesthesia or arthroscopic arthrolysis. There are few other complications reported and to date secondary necrosis of the trochlea has not been reported. Technically speaking, the deepening trochleoplasty is a difficult procedure without reliable landmarks. We propose a recession wedge trochleoplasty which is an easier procedure. It is never undertaken as an isolated procedure, but always in conjunction with other realignment procedures of the extensor apparatus according to the "a la carte" surgery concept.

  13. Process for obtaining ammonium uranyl tri carbonate

    International Nuclear Information System (INIS)

    Santos, L.R. dos; Riella, H.G.

    1992-01-01

    The procedure adopted for obtaining Ammonium Uranyl Carbonate (AUC) from uranium hexafluoride (U F 6 ) in a aqueous solutions of ammonium hydrogen carbonate is described in this work. The precipitation is made in temperature and pH controlled. This process consists of three steps: evaporation of U F 6 , AUC precipitation and filtration of the AUC slurry. An attempt is made of correlate the parameters involved in the precipitation process of AUC with its and U O 2 characteristics. (author)

  14. Superconducting materials fabrication process and materials obtained

    International Nuclear Information System (INIS)

    Lafon, M.O.; Magnier, C.

    1989-01-01

    The preparation process of a fine powder of YBaCuO type superconductors of easy sintering comprises: mixing in presence of alcohol an aqueous solution of rare earth nitrate or acetate, alkaline earth nitrate or acetate and copper nitrate or acetate and an oxalic acid solution, the pH value of the mixture is comprised between 2 and 4, the obtained precipitate is separated, dried, calcined and eventually crushed [fr

  15. PULP OBTAINING METHOD FOR PACKAGE PRODUCTION

    Directory of Open Access Journals (Sweden)

    V. V. Kuzmich

    2015-01-01

    Full Text Available The paper presents a new method for obtaining pulp which is used for production of cardboard, paper and package while using carbon dioxide and hydrazine hydrate and neutral-sulfite  shive cooking. Output increase of  the desired product can be explained by reduction in destruction of plant raw material carbohydrates during its cooking process. Quality improvement of the desired product (improvement in bleaching and output is attributed to the fact that usage of carbon dioxide and hydrazine contributes to provision of polysaccharide chain resistance to destruction due to the presence of  end links having structure of metasaccharinic and aldonic acids.The author has developed a new method for pulp obtaining on the basis of the executed investigations  and literature data.  СО2 and hydrazine hydrate have been used for obtaining pulp. Method invention concerns pulp obtaining and it can be used for paper and cardboard package manufacturing in pulp and paper industry.The method is to be carried in the following way: pulp-containing plant raw material is loaded into an autoclave and then aqua solution of sodium monosulfite containing hydrazine hydrate that constitutes 4–5 % of absolute dry pulp-containing raw material mass with liquid module 1:6–1:8 is supplied into the autoclave. The autoclave is closed for operation under pressure and the solution is carbonated under pressure which constitutes 5–8 % of absolute dry plant raw material (shover. Temperature is subsequently raised up to 180 °С in the space of 2 hours and cooking is carried out in the course of 4 hours. Usage of  the proposed method for shover cooking makes it possible to reduce monosulfite cooking process and improve qualitative characteristics and output of the desired product.  In addition to above mentioned fact there is a possibility to improve bleaching and final product output. 

  16. Interdisciplinary Project Experiences: Collaboration between Majors and Non-Majors

    Science.gov (United States)

    Smarkusky, Debra L.; Toman, Sharon A.

    2014-01-01

    Students in computer science and information technology should be engaged in solving real-world problems received from government and industry as well as those that expose them to various areas of application. In this paper, we discuss interdisciplinary project experiences between majors and non-majors that offered a creative and innovative…

  17. Program analysis and presentation of results of the profiles and depth dose rates obtained with the PTW software MC{sub 2} MEPHYSTO; Programa de analisis y presentacion de resultados de los perfiles y porcentajes de dosis en profundidad adquiridos con el software MEPHYSTO MC2 de PTW

    Energy Technology Data Exchange (ETDEWEB)

    Tato de la Cuevas, F.

    2011-07-01

    In the periodic quality control of linear accelerators is usually included acquisition and analysis of profiles and PDDs (percentage depth dose). In the protocol of Quality Control of electron accelerators for clinical use of the proposed analysis SEFM 4 Profiles for each of the energies used clinically. This involves a large number of curves to be analyzed and the subsequent introduction of the parameters in a spreadsheet or similar for your assessment as to the reference state. We have developed a program that analyzes the curves acquired by mcc Mephysto PTW software and presents the results of that analysis in a spreadsheet.

  18. Cost analysis of paroxetine versus imipramine in major depression.

    Science.gov (United States)

    Bentkover, J D; Feighner, J P

    1995-09-01

    A simulation decision analytical model was used to compare the annual direct medical costs of treating patients with major depression using the selective serotonin reuptake inhibitor (SSRI) paroxetine or the tricyclic antidepressant (TCA) imipramine. Medical treatment patterns were determined from focus groups of general and family practitioners and psychiatrists in Boston, Dallas and Chicago, US. Direct medical costs included the wholesale drug acquisition costs (based on a 6-month course of drug therapy), psychiatrist and/or general practitioner visits, hospital outpatient visits, hospitalisation and electroconvulsive therapy. Acute phase treatment failure rates were derived from an intention-to-treat analysis of a previously published trial of paroxetine, imipramine and placebo in patients with major depression. Maintenance phase relapse rates were obtained from a 12-month trial of paroxetine, supplemented from the medical literature. The relapse rates for the final 6 months of the year were obtained from medical literature and expert opinion. Direct medical costs were estimated from a health insurance claims database. The estimated total direct medical cost per patient was slightly lower using paroxetine ($US2348) than generic imipramine ($US2448) as first-line therapy. This result was sensitive to short term dropout rates but robust to changes in other major parameters, including hospitalisation costs and relapse rates. The financial benefit of paroxetine, despite its 15-fold higher acquisition cost compared with imipramine, is attributable to a higher rate of completion of the initial course of therapy and consequent reduced hospitalisation rates.

  19. Do Biology Majors Really Differ from Non-STEM Majors?

    Science.gov (United States)

    Cotner, Sehoya; Thompson, Seth; Wright, Robin

    2017-01-01

    Recent calls to action urge sweeping reform in science education, advocating for improved learning for all students-including those majoring in fields beyond the sciences. However, little work has been done to characterize the differences-if any exist-between students planning a career in science and those studying other disciplines. We describe an attempt to clarify, in broad terms, how non-STEM (science, technology, engineering, and mathematics) majors differ from life sciences majors, and how they are similar. Using survey responses and institutional data, we find that non-STEM majors are not unilaterally science averse; non-STEM majors are more likely than biology majors to hold misconceptions about the nature of science, yet they are not completely ignorant of how science works; non-STEM majors are less likely than biology majors to see science as personally relevant; and non-STEM majors populations are likely to be more diverse-with respect to incoming knowledge, perceptions, backgrounds, and skills-than a biology majors population. We encourage science educators to consider these characteristics when designing curricula for future scientists or simply for a well-informed citizenry. © 2017 S. Cotner et al. CBE—Life Sciences Education © 2017 The American Society for Cell Biology. This article is distributed by The American Society for Cell Biology under license from the author(s). It is available to the public under an Attribution–Noncommercial–Share Alike 3.0 Unported Creative Commons License (http://creativecommons.org/licenses/by-nc-sa/3.0).

  20. Propensity for obtaining alcohol through shoulder tapping.

    Science.gov (United States)

    Toomey, Traci L; Fabian, Lindsey E A; Erickson, Darin J; Lenk, Kathleen M

    2007-07-01

    Underage youth often obtain alcohol from adults who illegally provide the alcohol. One method for obtaining alcohol from adults is shoulder tapping, where youth approach an adult outside an alcohol establishment and ask the adult to purchase alcohol for them. The goal of this study was to assess what percentage of the general and youth-targeted adult population approached outside of a convenience/liquor store will agree to purchase and then provide alcohol to individuals who appear under age 21. We conducted 2 waves of pseudo-underage shoulder tap request attempts, using requesters who were age 21 or older but appeared 18 to 20 years old. In both waves, requests were conducted at randomly selected liquor and convenience stores, requesters explained that the reason they were asking the adult was because they did not have their identification with them, and requesters asked the adults to purchase a 6-pack of beer. During wave 1, we conducted 102 attempts, with the requester approaching the first adult entering the store alone. During wave 2, we conducted 102 attempts where the requester approached the first casually dressed male entering the store alone who appeared to be 21 to 30 years old. During wave 1, 8% of the general sample of approached adults provided alcohol to the pseudo-underage requesters. The odds of adults providing alcohol in urban areas were 9.4 times greater than in suburban areas. During wave 2, 19% of the approached young men provided alcohol to the requesters. No requester, request attempt, establishment, or community characteristics were associated with request attempt outcomes during wave 2. A small percentage of the general population of adults will agree to provide alcohol to underage youth when approached outside an alcohol establishment. The likelihood of underage youth obtaining alcohol through shoulder tapping increases substantially if the youth approach young men.