WorldWideScience

Sample records for maintenance improving human

  1. Improving human performance in maintenance personnel

    International Nuclear Information System (INIS)

    Gonzalez Anez, Francisco; Agueero Agueero, Jorge

    2010-01-01

    The continuous evolution and improvement of safety-related processes has included the analysis, design and development of training plans for the qualification of maintenance nuclear power plant personnel. In this respect, the international references in this area recommend the establishment of systematic qualification programmes for personnel performing functions or carrying out safety related tasks. Maintenance personnel qualification processes have improved significantly, and training plans have been designed and developed based on Systematic Approach to Training methodology to each job position. These improvements have been clearly reflected in recent training programmes with new training material and training facilities focused not only on developing technical knowledge and skills but also on improving attitudes and safety culture. The objectives of maintenance training facilities such as laboratories, mock-ups real an virtual, hydraulic loops, field simulators and other training material to be used in the maintenance training centre are to cover training necessities for initial and continuous qualification. Evidently, all these improvements made in the qualification of plant personnel should be extended to include supplemental personnel (external or contracted) performing safety-related tasks. The supplemental personnel constitute a very spread group, covering the performance of multiple activities entailing different levels of responsibility. Some of these activities are performed permanently at the plant, while others are occasional or sporadic. In order to establish qualification requirements for these supplemental workers, it is recommended to establish a rigorous analysis of job positions and tasks. The objective will be to identify the qualification requirements to assure competence and safety. (authors)

  2. Proceedings of the workshop on better nuclear plant maintenance: improving human and organisational performance

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2007-04-05

    A significant proportion of nuclear plant events is attributable to failures that take place during maintenance and periodic testing. Human and organisational factors are frequently identified as making a major contribution to these events. Despite this recognition, licensee and regulatory oversight in the human and organisational area has tended to focus more on operational matters than maintenance. Owing to the importance of human and organisational performance on nuclear plant maintenance, the CSNI Special Experts' Group on Human and Organisational Factors (SEGHOF) hosted a workshop entitled 'Better nuclear plant maintenance: improving human and organisational performance'. The workshop provided an international forum for staff from nuclear plants, research bodies, and regulators to discuss human and organisational challenges to maintenance, and initiatives to support effective performance. Over 60 participants from about 20 countries participated. The workshop was divided into five sessions: 1) International guidance to improve maintenance performance; 2) Lessons learned through maintenance operating experience; 3) Licensee initiatives to support reliable maintenance; 4) Regulatory approaches to assuring effective licensee maintenance; and 5) Recent trends and their impact on maintenance. Sessions commenced with oral presentations of papers followed by break-out and plenary discussions. Session 4 on regulatory approaches included short presentations from ten regulatory bodies and was followed by discussion comparing these approaches. The main findings of the workshop concern: the retirements of experienced staff; the increasing use of contractors to perform maintenance activities; the use of skill-broadening in maintenance; the role of supervisors at the plant level; the organisational changes that are used to optimise the use of plant staff resources; the effective planning of maintenance tasks; the time allowed to complete maintenance tasks; the development

  3. Latent human error analysis and efficient improvement strategies by fuzzy TOPSIS in aviation maintenance tasks.

    Science.gov (United States)

    Chiu, Ming-Chuan; Hsieh, Min-Chih

    2016-05-01

    The purposes of this study were to develop a latent human error analysis process, to explore the factors of latent human error in aviation maintenance tasks, and to provide an efficient improvement strategy for addressing those errors. First, we used HFACS and RCA to define the error factors related to aviation maintenance tasks. Fuzzy TOPSIS with four criteria was applied to evaluate the error factors. Results show that 1) adverse physiological states, 2) physical/mental limitations, and 3) coordination, communication, and planning are the factors related to airline maintenance tasks that could be addressed easily and efficiently. This research establishes a new analytic process for investigating latent human error and provides a strategy for analyzing human error using fuzzy TOPSIS. Our analysis process complements shortages in existing methodologies by incorporating improvement efficiency, and it enhances the depth and broadness of human error analysis methodology. Copyright © 2015 Elsevier Ltd and The Ergonomics Society. All rights reserved.

  4. Human factors interventions to reduce human errors and improve productivity in maintenance tasks

    International Nuclear Information System (INIS)

    Isoda, Hachiro; Yasutake, J.Y.

    1992-01-01

    This paper describes work in progress to develop interventions to reduce human errors and increase maintenance productivity in nuclear power plants. The effort is part of a two-phased Human Factors research program being conducted jointly by the Central Research Institute of Electric Power Industry (CRIEPI) in Japan and the Electric Power Research Institute (EPRI) in the United States. The overall objective of this joint research program is to identify critical maintenance tasks and to develop, implement and evaluate interventions which have high potential for reducing human errors or increasing maintenance productivity. As a result of the Phase 1 effort, ten critical maintenance tasks were identified. For these tasks, over 25 candidate interventions were identified for potential development. After careful analysis, seven interventions were selected for development during Phase 2. This paper describes the methodology used to analyze and identify the most critical tasks, the process of identifying and developing selected interventions and some of the initial results. (author)

  5. Maintenance improvement program

    International Nuclear Information System (INIS)

    Derbonne, D.R.; Plunkett, T.F.; Simpson, J.R.

    1989-01-01

    During fuel cycle 1 at River Bend station, considerable effort was expended to reduce corrective maintenance work orders (MWOs) to <1,000. This was done by complementing the plant staff with costly contract personnel. Coming out of the first refueling outage, most contract personnel were released. The change in MWO backlog started a steady rise. It became readily apparent that to avoid costly contract staff time, a maintenance improvement program (MIP) was necessary. The MIP Was primarily directed at two areas: crew efficiency improvements and improved preplanned MWO packages. The overall effect of the MIP was to achieve significant productivity improvements with reduced operation and maintenance cost by providing frequent accountability to all levels of maintenance supervision. The MIP also produced a feeling of pride among the maintenance department employees that had not really existed before. This was the best benefit of all

  6. A human factors approach to effective maintenance

    International Nuclear Information System (INIS)

    Penington, J.; Shakeri, S.

    2006-01-01

    Traditionally in the field of Human Factors within the nuclear industry, the focus has been to identify the potential for human errors in operating tasks, and develop strategies to prevent their occurrence, provide recovery mechanisms, and mitigate the consequences of error as appropriate. Past experience has demonstrated however a significant number of human errors within the nuclear industry occur during maintenance tasks. It is for this reason, and the fact that our nuclear power plants are ageing and increasingly in need of maintenance, that the industry must pay more attention to maintenance tasks. The purpose of this paper is to present a framework for effective maintenance programs, and based upon this framework discuss an approach (an audit tool) that can be used to both design such a program, and to assess existing programs. In addition, this tool can form the basis of cost benefit decisions relating to priorities for improvements to existing programs. (author)

  7. The human factor in maintenance work

    International Nuclear Information System (INIS)

    Hansson, B.

    1996-01-01

    In most of the maintenance works performed at operating plants, the personnel is the warranty for both efficient performance and good quality. To reach the right quality level in performance, the personnel needs adequate tools and of course a maintenance strategy and an organisation that supports the efficient work. The human factor is mostly referred to when something went wrong and analyses are done. There is a great potential of doing preventive analysis. The presentation will focus on experience in this field and what has been done at Barsebaeck NPP to analyse and improve the maintenance work. As maintenance work can't be seen as an isolated area, the rest of the plant organisation is included in the presentation. (author) figs., tabs

  8. Human errors related to maintenance and modifications

    International Nuclear Information System (INIS)

    Laakso, K.; Pyy, P.; Reiman, L.

    1998-01-01

    about weakness in audits made by the operating organisation and in tests relating to plant operation. The number of plant-specific maintenance records used as input material was high and the findings were discussed thoroughly with the plant maintenance personnel. The results indicated that instrumentation is more prone to human error than the rest of maintenance. Most errors stem from refuelling outage periods and about a half of them were identified during the same outage they were committed. Plant modifications are a significant source of common cause failures. The number of dependent errors could be reduced by improved co-ordination and auditing, post-installation checking, training and start-up testing programmes. (orig.)

  9. Maintenance performance improvement with System Dynamics : A Corrective Maintenance showcase

    NARCIS (Netherlands)

    Deenen, R.E.M.; Van Daalen, C.E.; Koene, E.G.C.

    2008-01-01

    This paper presents a case study of an analysis of a Corrective Maintenance process to realize performance improvement. The Corrective Maintenance process is supported by SAP, which has indicated the performance realisation problem. System Dynamics is used in a Group Model Building process to

  10. Residual life management. Maintenance improvement

    International Nuclear Information System (INIS)

    Sainero Garcia, J.; Hevia Ruperez, F.

    1995-01-01

    The terms Residual Life Management, Life Cycle Management and Long-Term Management are synonymous with a concept which aims to establish efficient maintenance for the profitable and safe operation of a power plant for as long as possible. A Residual Life Management programme comprises a number of stages, of which Maintenance Evaluation focuses on how power plant maintenance practices allow the mitigation and control of component ageing. with this objective in mind, a methodology has been developed for the analysis of potential degradative phenomena acting on critical components in terms of normal power plant maintenance practices. This methodology applied to maintenance evaluation enables the setting out of a maintenance programme based on the Life Management concept, and the programme's subsequent up-dating to allow for new techniques and methods. Initial applications have shown that although, in general terms, power plant maintenance is efficient, the way in which Residual Life Management is approached requires changes in maintenance practices. These changes range from modifications to existing inspection and surveillance methods or the establishment of new ones, to the monitoring of trends or the performance of additional studies, the purpose of which is to provide an accurate evaluation of the condition of the installations and the possibility of life extension. (Author)

  11. Spares management for improved maintenance

    International Nuclear Information System (INIS)

    Moncrief, E.C.; Schroder, R.M.

    1987-01-01

    A recent survey by the US Nuclear Regulatory Commission (NRC) of maintenance practices at US nuclear power plants confirms that spare parts availability is, to some extent, a problem at all but a few plants, and that 57% of the plants sometimes operated in a limiting condition for operation over the last year due to unavailability of spare parts. That's the bad news. The good news is that significant improvement is possible without ballooning inventory. The vast majority of total dollar value of spare parts inventory at power generation stations, whether nuclear or fossil, is rarely used (parts or components that are used 12 or less times per year including many with a history of no use for many years). Inventory Solutions of Akron, Ohio, has developed such a tool, called rarely used inventory stocking logic (RUSL) which is a user-friendly decision support tool for setting spare parts reorder points. Based on statistical computations enhanced to include the most advanced techniques developed for use in aerospace and military combat readiness, RUSL calculates the optimum stocking level to achieve the desired spare part availability at the station. In doing so, it considers the importance of the part in preventing an outage, as well as key economic ordering parameters, such as part cost, carrying cost, number of parts in service, historical observed usage, anticipated future usage, and lead time to replenish

  12. Software Maintenance Management Evaluation and Continuous Improvement

    CERN Document Server

    April, Alain

    2008-01-01

    This book explores the domain of software maintenance management and provides road maps for improving software maintenance organizations. It describes full maintenance maturity models organized by levels 1, 2, and 3, which allow for benchmarking and continuous improvement paths. Goals for each key practice area are also provided, and the model presented is fully aligned with the architecture and framework of software development maturity models of CMMI and ISO 15504. It is complete with case studies, figures, tables, and graphs.

  13. Improving industrial maintenance contract relationships

    NARCIS (Netherlands)

    De Jong, A.

    2010-01-01

    Unavailability of technical systems, such as aircraft, is expensive. Technical systems require maintenance to prevent and to remedy defects that cause unavailability. Users of technical systems usually bear the consequences of the risk of unavailability, in particular the loss of productivity. This

  14. Improving Minuteman III Maintenance Concepts

    Science.gov (United States)

    2017-03-23

    the ground . Then figure out what your challenges are. We’ll have those” (Pappalardo, 2011). Another challenge facing the maintenance personnel...as assets aged as indicated by the pattern ‘B’ shown in Figure 2. With the increase in the mechanization of processes, more attention has been...concepts could be applied to the sustainment of the MM III as well as benefit its planned replacement, the Ground Based Strategic Deterrent (GBDS

  15. Improving regulatory oversight of maintenance programs

    International Nuclear Information System (INIS)

    Cook, S.

    2008-01-01

    Safe nuclear power plant operation requires that risks due to failure or unavailability of Structures, Systems and Components (SSCs) be minimized. Implementation of an effective maintenance program is a key means for achieving this goal. In its regulatory framework, the important relationship between maintenance and safety is acknowledged by the CNSC. A high level maintenance program requirement is included in the Class I Facilities Regulations. In addition, the operating licence contains a condition based on the principle that the design function and performance of SSCs needs to remain consistent with the plant's design and analysis documents. Nuclear power plant licensees have the primary responsibility for safe operation of their facilities and consequently for implementation of a successful maintenance program. The oversight role of the Canadian Nuclear Safety Commission (CNSC) is to ensure that the licensee carries out that responsibility. The challenge for the CNSC is how to do this consistently and efficiently. Three opportunities for improvement to regulatory maintenance oversight are being pursued. These are related to the regulatory framework, compliance verification inspection activities and monitoring of self-reporting. The regulatory framework has been improved by clarifying expectations through the issuance of S-210 'Maintenance Programs for Nuclear Power Plants'. Inspection activities have been improved by introducing new maintenance inspections into the baseline program. Monitoring is being improved by making better use of self-reported and industry produced maintenance related performance indicators. As with any type of program change, the challenge is to ensure the consistent and optimal application of regulatory activities and resources. This paper is a summary of the CNSC's approach to improving its maintenance oversight strategy. (author)

  16. Cloud Computing for Maintenance Performance Improvement

    OpenAIRE

    Kour, Ravdeep; Karim, Ramin; Parida, Aditya

    2013-01-01

    Cloud Computing is an emerging research area. It can be utilised for acquiring an effective and efficient information logistics. This paper uses cloud-based technology for the establishment of information logistics for railway system which requires information based on data from different data sources (e.g. railway maintenance, railway operation, and railway business data). In order to improve the performance of the maintenance process relevant data from various sources need to be acquired, f...

  17. Maintenance system improvement in cast iron foundry

    Directory of Open Access Journals (Sweden)

    S. Kukla

    2011-07-01

    Full Text Available The work presents the issue of technical equipment management in an iron foundry basing on the assumptions of the TPM system (Total Productive Maintenance. Exploitation analysis of automatic casting lines has been carried out and their work’s influence on the whole production system’s functioning has been researched. Within maintenance system improvement, implementation of autonomic service and planned lines’ review have been proposed in order to minimize the time of breakdown stoppages. The SMED method was used to optimize changeover time, and the OEE (Overall Equipment Effectiveness was applied to evaluate the level of resources usage before and after implementing changes. Further, the influence of the maintenance strategy of casting devices’ efficiency on own costs of casting manufac- ture was estimated.

  18. Improving the TRIGA facility maintenance by predictive maintenance techniques

    International Nuclear Information System (INIS)

    Preda, M.; Sabau, C.; Barbalata, E.

    1997-01-01

    This work deals with the specific operation of equipment in radioactive environment or in conditions allowing radioactive contamination. The requirements of remote operation ensuring the operators' protection are presented. Also, the requirements of international standards issued by IAEA-Vienna are reviewed. The organizational withdraws of the maintenance activities, based on the standards and maintenance and repair directives still in force, are shown. It is emphasized the fact that this type of maintenance was adequate to a given level of technical development, characteristic for pre-computerized industry, but, at present, it is obsolete and uneconomic both in utilization and maintenance. Such a system constitutes already a burden hindering the efforts of maximizing the availability, maintenance, prolongation the service life of equipment and utilities, finally, of increasing the efficiency of complex installations. Moreover, the predictive maintenance techniques are strongly requested by the character of radioactive installations precluding the direct access in given zones (a potential risk of irradiation or radioactive contamination) of installations during operation. The results obtained by applying the predictive maintenance techniques in the operation of the double circuit irradiation loop, used in the TRIGA reactors, are presented

  19. Human Factors in Aviation Maintenance. Phase 1

    Science.gov (United States)

    1991-11-01

    solution is war- more effe-ctive use of human resoUrecs , the neat step Ls to ane- uassol o efogte.S a hr sn tes te de. Af piot progfctram can...and Subtitle 5. Report Date November 1991 Human Factors in Aviation Maintenance - Phase One Progress Report 6. Perfarng Oon z’on Code i8. Perfo-rrng...Independence Avenue, SW 14. Sponsor,mg Agency Code Washington, DC 20591 15. Supplementary Notes 16. Abstract "• This human factors research in aviation

  20. The contributions of human factors on human error in Malaysia aviation maintenance industries

    Science.gov (United States)

    Padil, H.; Said, M. N.; Azizan, A.

    2018-05-01

    Aviation maintenance is a multitasking activity in which individuals perform varied tasks under constant pressure to meet deadlines as well as challenging work conditions. These situational characteristics combined with human factors can lead to various types of human related errors. The primary objective of this research is to develop a structural relationship model that incorporates human factors, organizational factors, and their impact on human errors in aviation maintenance. Towards that end, a questionnaire was developed which was administered to Malaysian aviation maintenance professionals. Structural Equation Modelling (SEM) approach was used in this study utilizing AMOS software. Results showed that there were a significant relationship of human factors on human errors and were tested in the model. Human factors had a partial effect on organizational factors while organizational factors had a direct and positive impact on human errors. It was also revealed that organizational factors contributed to human errors when coupled with human factors construct. This study has contributed to the advancement of knowledge on human factors effecting safety and has provided guidelines for improving human factors performance relating to aviation maintenance activities and could be used as a reference for improving safety performance in the Malaysian aviation maintenance companies.

  1. Computerizing Maintenance Management Improves School Processes.

    Science.gov (United States)

    Conroy, Pat

    2002-01-01

    Describes how a Computerized Maintenance Management System (CMMS), a centralized maintenance operations database that facilitates work order procedures and staff directives, can help individual school campuses and school districts to manage maintenance. Presents the benefits of CMMS and things to consider in CMMS selection. (EV)

  2. Lean Maintenance Applied to Improve Maintenance Efficiency in Thermoelectric Power Plants

    OpenAIRE

    Orlando Duran; Andrea Capaldo; Paulo Andrés Duran Acevedo

    2017-01-01

    Thermoelectric power plants consist of a set of critical equipment that require high levels of availability and reliability. Due to this, maintenance of these physical assets is gaining momentum in industry. Maintenance is considered as an activity that contributes to improving the availability, efficiency and productivity of each piece of equipment. Several techniques have been used to achieve greater efficiencies in maintenance, among which we can find the lean maintenance philosophy. Despi...

  3. Performance Improvement through Implementation of Lean Maintenance

    OpenAIRE

    S. Kolanjiappan; Dr. K. Maran

    2011-01-01

    Lean Maintenance is a relatively new term, invented in the last decade of the twentieth century, but the principles are well established in Total Productive Maintenance (TPM). Lean Maintenance—taking its lead from Lean Manufacturing—applies some new techniques to TPM concepts to render a more structured implementation path. Tracing its roots back to Henry Ford with modern refinements born in Japanese manufacturing, specifically the Toyota Production System (TPS). Lean seeks to eliminate a...

  4. TRIZ method application for improving the special vehicles maintenance

    OpenAIRE

    Petrović Saša; Lozanović-Šajić Jasmina; Knežević Tijana; Pavlović Jovan; Ivanov Goran

    2014-01-01

    TRIZ methodology provides an opportunity for improving the classical engineering approach based on personal knowledge and experience. This paper presents the application of TRIZ methods for improving vehicle maintenance where special equipment is installed. A specific problem is the maintenance of the periscopes with heating system. Protective glass panels with heating system are rectangular glass elements. Their purpose is to perform mechanical protection ...

  5. Lean Maintenance Applied to Improve Maintenance Efficiency in Thermoelectric Power Plants

    Directory of Open Access Journals (Sweden)

    Orlando Duran

    2017-10-01

    Full Text Available Thermoelectric power plants consist of a set of critical equipment that require high levels of availability and reliability. Due to this, maintenance of these physical assets is gaining momentum in industry. Maintenance is considered as an activity that contributes to improving the availability, efficiency and productivity of each piece of equipment. Several techniques have been used to achieve greater efficiencies in maintenance, among which we can find the lean maintenance philosophy. Despite the wide diffusion of lean maintenance, there is no structured method that supports the prescription of lean tools applied to the maintenance function. This paper presents the experience gathered in two lean maintenance projects in thermoelectric power plants. The application of lean techniques was based on using a previously developed multicriterial decision making process that uses the Fuzzy Analytic Hierarchy Process (AHP methodology to carry out a diagnosis and prescription tasks. That methodology allowed the prescription of the appropriated lean techniques to resolve the main deficiencies in maintenance function. The results of applying such lean tools show that important results can be obtained, making the maintenance function in thermoelectric power plants more efficient and lean.

  6. Maintenance modeling and optimization integrating human and material resources

    International Nuclear Information System (INIS)

    Martorell, S.; Villamizar, M.; Carlos, S.; Sanchez, A.

    2010-01-01

    Maintenance planning is a subject of concern to many industrial sectors as plant safety and business depend on it. Traditionally, the maintenance planning is formulated in terms of a multi-objective optimization (MOP) problem where reliability, availability, maintainability and cost (RAM+C) act as decision criteria and maintenance strategies (i.e. maintenance tasks intervals) act as the only decision variables. However the appropriate development of each maintenance strategy depends not only on the maintenance intervals but also on the resources (human and material) available to implement such strategies. Thus, the effect of the necessary resources on RAM+C needs to be modeled and accounted for in formulating the MOP affecting the set of objectives and constraints. In this paper RAM+C models to explicitly address the effect of human resources and material resources (spare parts) on RAM+C criteria are proposed. This extended model allows accounting for explicitly how the above decision criteria depends on the basic model parameters representing the type of strategies, maintenance intervals, durations, human resources and material resources. Finally, an application case is performed to optimize the maintenance plan of a motor-driven pump equipment considering as decision variables maintenance and test intervals and human and material resources.

  7. Maintenance modeling and optimization integrating human and material resources

    Energy Technology Data Exchange (ETDEWEB)

    Martorell, S., E-mail: smartore@iqn.upv.e [Dpto. Ingenieria Quimica y Nuclear, Universidad Politecnica Valencia (Spain); Villamizar, M.; Carlos, S. [Dpto. Ingenieria Quimica y Nuclear, Universidad Politecnica Valencia (Spain); Sanchez, A. [Dpto. Estadistica e Investigacion Operativa Aplicadas y Calidad, Universidad Politecnica Valencia (Spain)

    2010-12-15

    Maintenance planning is a subject of concern to many industrial sectors as plant safety and business depend on it. Traditionally, the maintenance planning is formulated in terms of a multi-objective optimization (MOP) problem where reliability, availability, maintainability and cost (RAM+C) act as decision criteria and maintenance strategies (i.e. maintenance tasks intervals) act as the only decision variables. However the appropriate development of each maintenance strategy depends not only on the maintenance intervals but also on the resources (human and material) available to implement such strategies. Thus, the effect of the necessary resources on RAM+C needs to be modeled and accounted for in formulating the MOP affecting the set of objectives and constraints. In this paper RAM+C models to explicitly address the effect of human resources and material resources (spare parts) on RAM+C criteria are proposed. This extended model allows accounting for explicitly how the above decision criteria depends on the basic model parameters representing the type of strategies, maintenance intervals, durations, human resources and material resources. Finally, an application case is performed to optimize the maintenance plan of a motor-driven pump equipment considering as decision variables maintenance and test intervals and human and material resources.

  8. Identification of the human factors contributing to maintenance failures in a petroleum operation.

    Science.gov (United States)

    Antonovsky, Ari; Pollock, Clare; Straker, Leon

    2014-03-01

    This research aimed to identify the most frequently occurring human factors contributing to maintenance-related failures within a petroleum industry organization. Commonality between failures will assist in understanding reliability in maintenance processes, thereby preventing accidents in high-hazard domains. Methods exist for understanding the human factors contributing to accidents. Their application in a maintenance context mainly has been advanced in aviation and nuclear power. Maintenance in the petroleum industry provides a different context for investigating the role that human factors play in influencing outcomes. It is therefore worth investigating the contributing human factors to improve our understanding of both human factors in reliability and the factors specific to this domain. Detailed analyses were conducted of maintenance-related failures (N = 38) in a petroleum company using structured interviews with maintenance technicians. The interview structure was based on the Human Factor Investigation Tool (HFIT), which in turn was based on Rasmussen's model of human malfunction. A mean of 9.5 factors per incident was identified across the cases investigated.The three most frequent human factors contributing to the maintenance failures were found to be assumption (79% of cases), design and maintenance (71%), and communication (66%). HFIT proved to be a useful instrument for identifying the pattern of human factors that recurred most frequently in maintenance-related failures. The high frequency of failures attributed to assumptions and communication demonstrated the importance of problem-solving abilities and organizational communication in a domain where maintenance personnel have a high degree of autonomy and a wide geographical distribution.

  9. Assessment and improvement of urban streets maintenance: Case study Kragujevac

    Directory of Open Access Journals (Sweden)

    Jokanović Igor

    2017-01-01

    Full Text Available City of Kragujevac struggles with providing road maintenance services due to limited funds and low capacity within the existing Public Utility Companies. As a solution to problems with traditional methods of contracting, many road authorities have moved to contracting road maintenance works to the private sector based on performance measures. The paper presents the outcomes of the study conducted for the purpose of improving current practice and condition of urban network within the City of Kragujevac through the application of performance-based maintenance contracting.

  10. Maintenance of Improved Attitudes Toward Stuttering.

    Science.gov (United States)

    St Louis, Kenneth O; Flynn, Timothy W

    2018-05-03

    This study sought to determine the extent to which experimentally induced positive attitudes in high school students in a previous investigation were maintained 7 years later. Authors and assistants recruited 36 adults in their early 20s (Follow-up group) who, in high school, had witnessed either a live oral talk by a person who stutters or a professionally made video on stuttering designed for teens followed by a short talk by the same speaker. The Public Opinion Survey of Human Attributes-Stuttering was administered before and after the interventions in high school and 7 years later such that pre-post group comparisons were made. Previously, the Follow-up group had demonstrated highly positive changes in their attitudes after the interventions. In addition, a control group of 56 former high school students from the same state, who did not participate in the interventions, were recruited and compared to the Follow-up group. The Follow-up group, which was found to be representative of the original high school cohort, held more positive Public Opinion Survey of Human Attributes-Stuttering mean ratings than the Control group, although somewhat less positive than their previous postintervention ratings. The Follow-up group maintained many of the positive changes in their beliefs and self reactions regarding stuttering that were induced 7 years earlier after witnessing personal stories and facts about stuttering.

  11. Enhanced human performance of utility maintenance programs

    International Nuclear Information System (INIS)

    Fresco, A.; Haber, S.; O'Brien, J.

    1993-01-01

    Assuring the safe operation of a nuclear power plant depends, to a large extent, on how effectively one understands and manages the aging-related degradation that occurs in structures, systems, and components (SSCs). Aging-related degradation is typically managed through a nuclear plant's maintenance program. A review of 44 Maintenance Team Inspection (MTI) Reports indicated that while some plant organizations appeared to assume a proactive mode in preventing aging-related failures of their SSCs important to safety, others seemed to be taking a passive or reactive mode. Across all plants, what is clearly needed, is a strong recognition of the importance of aging-related degradation and the use of existing organizational assets to effectively detect and mitigate those effects. Many of those assets can be enhanced by the consideration of organizational and management factors necessary for the implementation of an effective aging management program. This report provides a discussion of this program

  12. Applying PPM to ERP Maintenance and Continuous Improvement Initiatives

    DEFF Research Database (Denmark)

    El-Tal, Nada Maria; Fonnesbæk, Majbrit; Kræmmergaard, Pernille

    2006-01-01

    to gain business benefits from the systems. However the ERP literature on how to do this is limited. The purpose of this article is to explore how Project Portfolio Management (PPM) from the Research and Development (R&D) literature can be applied to an ERP second wave context, when companies...... are to prioritize and select maintenance and continuous improvement initiatives. This is done by reviewing the existing literature in the fields of PPM from R&D literature and then by reviewing the existing literature about maintenance and improvement initiatives in the ERP literature, after which the two...... are compared and discussed using three case-studies. The paper contributes with a discussion on how PPM from R&D can be applied to maintenance and continuous improvement initiatives in the second wave of ERP. The paper ends with arguing that emphasis needs to be given to this field, since a conscious...

  13. TRIZ method application for improving the special vehicles maintenance

    Directory of Open Access Journals (Sweden)

    Petrović Saša

    2014-01-01

    Full Text Available TRIZ methodology provides an opportunity for improving the classical engineering approach based on personal knowledge and experience. This paper presents the application of TRIZ methods for improving vehicle maintenance where special equipment is installed. A specific problem is the maintenance of the periscopes with heating system. Protective glass panels with heating system are rectangular glass elements. Their purpose is to perform mechanical protection of built-in prisms and provide heating of the prisms. Aging and long-term use leads to failure of these elements. The practice requires solutions in order to extend the lifetime of the system. New solution is evaluated by simulation and experiment.

  14. Developing Predictive Maintenance Expertise to Improve Plant Equipment Reliability

    International Nuclear Information System (INIS)

    Wurzbach, Richard N.

    2002-01-01

    On-line equipment condition monitoring is a critical component of the world-class production and safety histories of many successful nuclear plant operators. From addressing availability and operability concerns of nuclear safety-related equipment to increasing profitability through support system reliability and reduced maintenance costs, Predictive Maintenance programs have increasingly become a vital contribution to the maintenance and operation decisions of nuclear facilities. In recent years, significant advancements have been made in the quality and portability of many of the instruments being used, and software improvements have been made as well. However, the single most influential component of the success of these programs is the impact of a trained and experienced team of personnel putting this technology to work. Changes in the nature of the power generation industry brought on by competition, mergers, and acquisitions, has taken the historically stable personnel environment of power generation and created a very dynamic situation. As a result, many facilities have seen a significant turnover in personnel in key positions, including predictive maintenance personnel. It has become the challenge for many nuclear operators to maintain the consistent contribution of quality data and information from predictive maintenance that has become important in the overall equipment decision process. These challenges can be met through the implementation of quality training to predictive maintenance personnel and regular updating and re-certification of key technology holders. The use of data management tools and services aid in the sharing of information across sites within an operating company, and with experts who can contribute value-added data management and analysis. The overall effectiveness of predictive maintenance programs can be improved through the incorporation of newly developed comprehensive technology training courses. These courses address the use of

  15. Discussing the Effective Factors on Maintenance of Human Resources

    OpenAIRE

    Bahare Shahriari

    2016-01-01

    In this research, the author has elaborated on detection of effective factors on maintenance and retention of human resources. Since human resources are the most resources for obtaining competitive advantage, it is essential to pay attention to different dimensions of human resources management. One of these dimensions is retention of human resources. Factors such as providing correct and valid information at the time of recruitment, assigning tasks based on competence, existence of a clear c...

  16. Human Error Probability Assessment During Maintenance Activities of Marine Systems

    Directory of Open Access Journals (Sweden)

    Rabiul Islam

    2018-03-01

    Full Text Available Background: Maintenance operations on-board ships are highly demanding. Maintenance operations are intensive activities requiring high man–machine interactions in challenging and evolving conditions. The evolving conditions are weather conditions, workplace temperature, ship motion, noise and vibration, and workload and stress. For example, extreme weather condition affects seafarers' performance, increasing the chances of error, and, consequently, can cause injuries or fatalities to personnel. An effective human error probability model is required to better manage maintenance on-board ships. The developed model would assist in developing and maintaining effective risk management protocols. Thus, the objective of this study is to develop a human error probability model considering various internal and external factors affecting seafarers' performance. Methods: The human error probability model is developed using probability theory applied to Bayesian network. The model is tested using the data received through the developed questionnaire survey of >200 experienced seafarers with >5 years of experience. The model developed in this study is used to find out the reliability of human performance on particular maintenance activities. Results: The developed methodology is tested on the maintenance of marine engine's cooling water pump for engine department and anchor windlass for deck department. In the considered case studies, human error probabilities are estimated in various scenarios and the results are compared between the scenarios and the different seafarer categories. The results of the case studies for both departments are also compared. Conclusion: The developed model is effective in assessing human error probabilities. These probabilities would get dynamically updated as and when new information is available on changes in either internal (i.e., training, experience, and fatigue or external (i.e., environmental and operational conditions

  17. Improvement of industrial efficiency by knowledge management in maintenance engineering

    Directory of Open Access Journals (Sweden)

    Carlos Alberto Mariotoni

    2015-09-01

    Full Text Available This article shows research and studies dealing with the management of knowledge in industrial maintenance engineering, developed in the field of applied research in real industrial companies of Europe, which are the consequences of  having knowledge on islands, as well as measures improvements when there is an adequate knowledge management. The peculiarities which are given in the maintenance of the company departments, knowledge of operators and technicians operating in these areas, is heavily based on their experiences (strong tacit component, what is difficult to measure and articulate, and however, on numerous occasions, this break from the knowledge, can impose a high cost for the industry.

  18. Improved Nuclear Power Plant maintenance. Application to Cofrentes NPP

    International Nuclear Information System (INIS)

    Serradell, V.

    2002-01-01

    The Industrial Safety and Environment Group (MEDASEGI) of the Valencia Polytechnic University (UPV) develops its activities in the fields of environmental radioactivity metrology and risk analysis and management aimed at improving industrial safety. The different lines of research developed by this group include collaboration with Cofrentes NPP. This collaboration began in 1993 and has primarily focused on issues related to improved maintenance and currently on life management. (Author)

  19. Human error in maintenance: An investigative study for the factories of the future

    International Nuclear Information System (INIS)

    Dhillon, B S

    2014-01-01

    This paper presents a study of human error in maintenance. Many different aspects of human error in maintenance considered useful for the factories of the future are studied, including facts, figures, and examples; occurrence of maintenance error in equipment life cycle, elements of a maintenance person's time, maintenance environment and the causes for the occurrence of maintenance error, types and typical maintenance errors, common maintainability design errors and useful design guidelines to reduce equipment maintenance errors, maintenance work instructions, and maintenance error analysis methods

  20. IMPROVING THE QUALITY OF MAINTENANCE PROCESSES USING INFORMATION TECHNOLOGY

    Directory of Open Access Journals (Sweden)

    Zora Arsovski

    2008-06-01

    Full Text Available In essence, process of maintaining equipment is a support process, because it indirectly contributes to operational ability of the production process necessary for the supply chain of the new value. Taking into account increased levels of automatization and quality, this proces s becomes more and more significant and for some branches of industry, even crucial. Due to the fact that the quality of the entire process is more and more dependent on the maintenance process, these processes must be carefully designed and effectively im plemented. There are various techniques and approaches at our disposal, such as technical, logistical and intensive application of the information - communication technologies. This last approach is presented in this work. It begins with organizational goa ls, especially quality objectives. Then, maintenance processes and integrated information system structures are defined. Maintenance process quality and improvement processes are defined using a set of performances, with a special emphasis placed on effectiveness and quality economics. At the end of the work, information system for improving maintenance economics is structured. Besides theoretical analysis, work also presents results authors obtained analyzing food industry, metal processing industry an d building materials industry.

  1. Basic study of the plant maintenance model considering plant improvement/modification

    International Nuclear Information System (INIS)

    Tsumaya, Akira; Inoue, Kazuya; Mochizuki, Masahito; Wakamatsu, Hidefumi; Arai, Eiji

    2007-01-01

    This paper proposes a maintenance activity model that considers not only routine maintenance activity but also functional maintenance including improvement/modification. Required maintenance types are categorized, and limitation of Activity Domain Integration Diagram (ADID) proposed by ISO18435 are discussed based on framework for life cycle maintenance management of manufacturing assets. Then, we proposed extension ADID model for plant maintenance activity model considering functional improvement/modification. (author)

  2. Predictive Maintenance: One key to improved power plant availability

    International Nuclear Information System (INIS)

    Mobley; Allen, J.W.

    1986-01-01

    Recent developments in microprocessor technology has provided the ability to routinely monitor the actual mechanical condition of all rotating and reciprocating machinery and process variables (i.e. pressure, temperature, flow, etc.) of other process equipment within an operating electric power generating plant. This direct correlation between frequency domain vibration and actual mechanical condition of machinery and trending process variables of non-rotating equipment can provide the ''key'' to improving the availability and reliability, thermal efficiency and provide the baseline information necessary for developing a realistic plan for extending the useful life of power plants. The premise of utilizing microprocessor-based Predictive Maintenance to improve power plant operation has been proven by a number of utilities. This paper provides a comprehensive discussion of the TEC approach to Predictive Maintenance and examples of successful programs

  3. Advances in new WWER designs to improve operation and maintenance

    International Nuclear Information System (INIS)

    Dragunov, Y.G.; Ryzhov, S.B.; Podshibiakin, A.K.; Vasilchenko, I.N.; Repin, A.I.; Nikitenko, M.P.; Konoplev, N.P.; Fil, N.S.

    2000-01-01

    Economic operational indices of WWER-type reactors show their competitiveness in all the countries where these reactors operate. Advanced WWERs being designed and constructed now have the improved characteristics of economical efficiency and are more convenient for operation and maintenance. Many technical solutions aimed at improvement of the operational performance are implemented in the design of WWER-1000/V-392 and WWER-640/V-407, and these reactors are the important basis for the nuclear power expansion in Russia. Some of these solutions are considered in the present paper. (author)

  4. Improvement of nuclear power plant operation and maintenance in Japan

    International Nuclear Information System (INIS)

    Kazushige Hamazaki

    1987-01-01

    Following the inauguration of commercial nuclear power generation in Japan in 1966, capacity factors were held in the relatively low level until around 1975 due to initial-period troubles. With subsequent improvement, however, capacity factors have climbed steadily and recently been sustaining more than 70%. To obtain this successful result, a various kind of improvement have been made not only for the operation management area but also for the maintenance management area in conjunction with the successive effort to reflect the operating experiences to the early stage design. Nowadays nuclear generation has assumed increasing importance for Japan's electrical power needs, and is making a great contribution to stabilizing power supply costs. (author)

  5. A study on human performance enhancement plan in maintenance field by survey on actual condition of human performance tools - 15035

    International Nuclear Information System (INIS)

    Park, J.; Jeong, H.; Kim, Y.

    2015-01-01

    Human errors in nuclear power plant are one of the important factors that may cause reactor trip. Most operating companies of nuclear power plants manage human factor systematically through tools like HPES (Human Performance Enhancement), PSR (Periodic Safety Review), OE (Operating Experience), human performance tools, safety culture assessment and CAP (Corrective Action Program). But human factors are managed passively in maintenance field, because maintenance works are carrying out by partner companies. KHNP also contracts the maintenance work to the partner companies, and advise them to use human performance tools. But the actual condition on partner companies has not been surveyed. This paper suggests some plans that can improve human performance by analyzing the opinion of partner company employees about the causes and solutions of human errors, by analyzing utilization of human performance tools and by comparing the results of the partner companies survey with the results of the operating company survey. The survey is conducted to 3 partner companies by similar contents and categories in order to compare partner company with operating company, and the main analysis fields are the following: -1) Level of understanding and utilization of the human performance tools, -2) Difficulties of applying the human performance tools, -3) Level of employee's training (or education) in the use of the human performance tools, and -4) Root causes of human errors and countermeasures. (authors)

  6. Improvement of testing and maintenance based on fault tree analysis

    International Nuclear Information System (INIS)

    Cepin, M.

    2000-01-01

    Testing and maintenance of safety equipment is an important issue, which significantly contributes to safe and efficient operation of a nuclear power plant. In this paper a method, which extends the classical fault tree with time, is presented. Its mathematical model is represented by a set of equations, which include time requirements defined in the house event matrix. House events matrix is a representation of house events switched on and off through the discrete points of time. It includes house events, which timely switch on and off parts of the fault tree in accordance with the status of the plant configuration. Time dependent top event probability is calculated by the fault tree evaluations. Arrangement of components outages is determined on base of minimization of mean system unavailability. The results show that application of the method may improve the time placement of testing and maintenance activities of safety equipment. (author)

  7. Implementing a customer focused continual business improvement program to improve the maintenance process

    International Nuclear Information System (INIS)

    Kharshafdjian, G.; Fisher, C.; Beres, T.; Brooks, S.; Forbes, S.; Krause, M.; McAuley, K.; Wendorf, M.

    2006-01-01

    Global market pressures and increasing competition demands that successful companies establish a continual business improvement program as part of implementing its business strategy. Such programs must be driven by the definition of quality from the customer's perspective. This customer quality focus often requires a change in all aspects of the business including products, services, processes and culture. This paper will describe how Atomic Energy of Canada Limited implemented a Continual Business Improvement Program in their Nuclear Laboratories Business Unit. In particular, to review how the techniques were applied to improve the maintenance process and the status of the project. Customer (internal users of the processes at CRL) feedback has shown repeatedly there is dissatisfaction of the maintenance process. Customers complain about jobs not getting done to schedule or being deferred. A project has been launched with the following goals: to improve the maintenance process customer satisfaction and increase trades wrench time by 30 minutes / trade / day. DMAIC (Define-Measure-Analyze-Improve-Control) methodology was applied to find out the Root Cause(s) of the problem, provide solutions, and implement improvements. The expected Operational Benefits include: Executing work efficiently to quality standards and business performance of the site, improve maintenance efficiencies, reduce cycle time for maintenance process and improve process yield, and improve customer and employee satisfaction. (author)

  8. Implementing a customer focused continual business improvement program to improve the maintenance process

    Energy Technology Data Exchange (ETDEWEB)

    Kharshafdjian, G.; Fisher, C.; Beres, T.; Brooks, S.; Forbes, S.; Krause, M.; McAuley, K.; Wendorf, M. [Atomic Energy of Canada Limited, Chalk River, Ontario (Canada)

    2006-07-01

    Global market pressures and increasing competition demands that successful companies establish a continual business improvement program as part of implementing its business strategy. Such programs must be driven by the definition of quality from the customer's perspective. This customer quality focus often requires a change in all aspects of the business including products, services, processes and culture. This paper will describe how Atomic Energy of Canada Limited implemented a Continual Business Improvement Program in their Nuclear Laboratories Business Unit. In particular, to review how the techniques were applied to improve the maintenance process and the status of the project. Customer (internal users of the processes at CRL) feedback has shown repeatedly there is dissatisfaction of the maintenance process. Customers complain about jobs not getting done to schedule or being deferred. A project has been launched with the following goals: to improve the maintenance process customer satisfaction and increase trades wrench time by 30 minutes / trade / day. DMAIC (Define-Measure-Analyze-Improve-Control) methodology was applied to find out the Root Cause(s) of the problem, provide solutions, and implement improvements. The expected Operational Benefits include: Executing work efficiently to quality standards and business performance of the site, improve maintenance efficiencies, reduce cycle time for maintenance process and improve process yield, and improve customer and employee satisfaction. (author)

  9. Systematic analysis of dependent human errors from the maintenance history at finnish NPPs - A status report

    Energy Technology Data Exchange (ETDEWEB)

    Laakso, K. [VTT Industrial Systems (Finland)

    2002-12-01

    Operating experience has shown missed detection events, where faults have passed inspections and functional tests to operating periods after the maintenance activities during the outage. The causes of these failures have often been complex event sequences, involving human and organisational factors. Especially common cause and other dependent failures of safety systems may significantly contribute to the reactor core damage risk. The topic has been addressed in the Finnish studies of human common cause failures, where experiences on latent human errors have been searched and analysed in detail from the maintenance history. The review of the bulk of the analysis results of the Olkiluoto and Loviisa plant sites shows that the instrumentation and control and electrical equipment is more prone to human error caused failure events than the other maintenance and that plant modifications and also predetermined preventive maintenance are significant sources of common cause failures. Most errors stem from the refuelling and maintenance outage period at the both sites, and less than half of the dependent errors were identified during the same outage. The dependent human errors originating from modifications could be reduced by a more tailored specification and coverage of their start-up testing programs. Improvements could also be achieved by a more case specific planning of the installation inspection and functional testing of complicated maintenance works or work objects of higher plant safety and availability importance. A better use and analysis of condition monitoring information for maintenance steering could also help. The feedback from discussions of the analysis results with plant experts and professionals is still crucial in developing the final conclusions and recommendations that meet the specific development needs at the plants. (au)

  10. Human cognitive task distribution model for maintenance support system of a nuclear power plant

    Energy Technology Data Exchange (ETDEWEB)

    Park, Young Ho

    2007-02-15

    In human factors research, more attention has been devoted to the operation of nuclear power plants (NPPs) than to their maintenance. However, human error related to maintenance is 45% among the total human errors from 1990 to 2005 in Korean nuclear power plants. Therefore, it is necessary to study human factors in the maintenance of an NPP. There is a current trend toward introducing digital technology into both safety and non-safety systems in NPPs. A variety of information about plant conditions can be used digitally. In the future, maintenance support systems will be developed based on an information-oriented NPP. In this context, it is necessary to study the cognitive tasks of the personnel involved in maintenance and the interaction between the personnel and maintenance support systems. The fundamental purpose of this work is how to distribute the cognitive tasks of the personnel involved in the maintenance in order to develop a maintenance support system that considers human factors. The second purpose is to find the causes of errors due to engineers or maintainers and propose system functions that are countermeasures to reduce these errors. In this paper, a cognitive task distribution model of the personnel involved in maintenance is proposed using Rasmussen's decision making model. First, the personnel were divided into three groups: the operators (inspectors), engineers, and maintainers. Second, human cognitive tasks related to maintenance were distributed based on these groups. The operators' cognitive tasks are detection and observation; the engineers' cognitive tasks are identification, evaluation, target state, select target, and procedure: and the maintainers' cognitive task is execution. The case study is an analysis of failure reports related to human error in maintenance over a period of 15years. By using error classification based on the information processing approach, the human errors involved in maintenance were classified

  11. Human cognitive task distribution model for maintenance support system of a nuclear power plant

    International Nuclear Information System (INIS)

    Park, Young Ho

    2007-02-01

    In human factors research, more attention has been devoted to the operation of nuclear power plants (NPPs) than to their maintenance. However, human error related to maintenance is 45% among the total human errors from 1990 to 2005 in Korean nuclear power plants. Therefore, it is necessary to study human factors in the maintenance of an NPP. There is a current trend toward introducing digital technology into both safety and non-safety systems in NPPs. A variety of information about plant conditions can be used digitally. In the future, maintenance support systems will be developed based on an information-oriented NPP. In this context, it is necessary to study the cognitive tasks of the personnel involved in maintenance and the interaction between the personnel and maintenance support systems. The fundamental purpose of this work is how to distribute the cognitive tasks of the personnel involved in the maintenance in order to develop a maintenance support system that considers human factors. The second purpose is to find the causes of errors due to engineers or maintainers and propose system functions that are countermeasures to reduce these errors. In this paper, a cognitive task distribution model of the personnel involved in maintenance is proposed using Rasmussen's decision making model. First, the personnel were divided into three groups: the operators (inspectors), engineers, and maintainers. Second, human cognitive tasks related to maintenance were distributed based on these groups. The operators' cognitive tasks are detection and observation; the engineers' cognitive tasks are identification, evaluation, target state, select target, and procedure: and the maintainers' cognitive task is execution. The case study is an analysis of failure reports related to human error in maintenance over a period of 15years. By using error classification based on the information processing approach, the human errors involved in maintenance were classified

  12. Using systematic aging assessments to improve effectiveness of plant maintenance programs

    International Nuclear Information System (INIS)

    Watson, P.; Yang, J.X.; Dam, R.F.; Nickerson, J.H.

    2003-01-01

    Nuclear plant equipment aging assessment studies provided by AECL include life assessments, condition assessments or systematic assessments of maintenance. AECL has developed several tools to apply the results of aging assessment studies to improve the effectiveness of actual plant maintenance programs. The Systematic Assessment of Maintenance and the SYSTMS tool generate maintenance tasks for a system. The System Maintenance Datastore tool assesses the maintenance resources on a system basis, and can thus quantify the savings realized by optimizing the maintenance program. Long term trends in condition-based maintenance due to component aging can be predicted, and resource savings due to optimum timing of component replacement or general plant refurbishment can be quantified. The System based Adaptive Maintenance Process ensures the maintenance program is continually updated to reflect the latest plant equipment condition and maintenance strategy information. (author)

  13. Improving nuclear power plant reliability through predictive maintenance

    International Nuclear Information System (INIS)

    Geilhausen, R.; Kunze, U.

    1996-01-01

    Maintenance strategies can be assigned to one of three categories: failure maintenance, periodic maintenance or condition-oriented maintenance. The optimum maintenance scheme can be selected on the basis of a cost-benefit analysis but the safety of life and limb or the political climate for NPP can hardly expressed in numbers. The implementation of preventive maintenance needs two preconditions: high-performance instrumentation in the form of stationary and mobile monitoring systems for the determination of the condition of the nuclear power plant components and provision of a tool that can handle both the organization of the work and the evaluation of the results obtained. (authors)

  14. Identifying Human Factors Issues in Aircraft Maintenance Operations

    Science.gov (United States)

    Veinott, Elizabeth S.; Kanki, Barbara G.; Shafto, Michael G. (Technical Monitor)

    1995-01-01

    Maintenance operations incidents submitted to the Aviation Safety Reporting System (ASRS) between 1986-1992 were systematically analyzed in order to identify issues relevant to human factors and crew coordination. This exploratory analysis involved 95 ASRS reports which represented a wide range of maintenance incidents. The reports were coded and analyzed according to the type of error (e.g, wrong part, procedural error, non-procedural error), contributing factors (e.g., individual, within-team, cross-team, procedure, tools), result of the error (e.g., aircraft damage or not) as well as the operational impact (e.g., aircraft flown to destination, air return, delay at gate). The main findings indicate that procedural errors were most common (48.4%) and that individual and team actions contributed to the errors in more than 50% of the cases. As for operational results, most errors were either corrected after landing at the destination (51.6%) or required the flight crew to stop enroute (29.5%). Interactions among these variables are also discussed. This analysis is a first step toward developing a taxonomy of crew coordination problems in maintenance. By understanding what variables are important and how they are interrelated, we may develop intervention strategies that are better tailored to the human factor issues involved.

  15. A predictive maintenance approach for improved nuclear plant availability

    International Nuclear Information System (INIS)

    Verma, R.M.P.; Pandya, M.B.; Kini, M.P.

    1979-01-01

    Predictive maintenance programme as against preventive maintenance programme aims at diagnosing, inspecting, monitoring, and objective condition-checking of equipment. It helps in forecasting failures, and scheduling the optimal frequencies for overhauls, replacements, lubrication etc. It also helps in establishing work load, manpower, resource planning and inventory control. Various stages of predictive maintenance programme for a nuclear power plant are outlined. A partial list of instruments for predictive maintenance is given. (M.G.B.)

  16. Human-centered automation of testing, surveillance and maintenance

    International Nuclear Information System (INIS)

    Bhatt, S.C.; Sun, B.K.H.

    1991-01-01

    Manual surveillance and testing of instrumentation, control and protection systems at nuclear power plants involves system and human errors which can lead to substantial plant down time. Frequent manual testing can also contribute significantly to operation and maintenance cost. Automation technology offers potential for prudent applications at the power plant to reduce testing errors and cost. To help address the testing problems and to harness the benefit of automation application, input from utilities is obtained on suitable automation approaches. This paper includes lessens from successful past experience at a few plants where some island of automation exist. The results are summarized as a set of specifications for semi automatic testing. A human-centered automation methodology is proposed with the guidelines for optimal human/computer division of tasks given. Implementation obstacles for significant changes of testing practices are identified and methods acceptable to nuclear power plants for addressing these obstacles have been suggested

  17. Improving the development, use and control of maintenance procedures

    International Nuclear Information System (INIS)

    Morgenstern, M.H.; Barnes, V.E.; Radford, L.R.; Wheeler, W.A.; Badalamente, R.V.

    1985-12-01

    This paper describes the results of a project conducted for the US Nuclear Regulatory Commission (NRC) to assess and document the need for guidance or regulatory involvement by the NRC in the development, upgrading, use and control of maintenance procedures in US nuclear power plants. Presented are the findings of the following activities: (1) a survey of current maintenance procedure practices in seven US nuclear power plants; (2) a review and analysis of plant administrative and maintenance procedures; (3) a survey of maintenance procedure practices in industries that share some characteristics with the nuclear industry; and (4) a review of the research pertaining to job performance aids and a brief analysis of their applicability to maintenance in nuclear power plants. Based on these findings, several recommendations to upgrade maintenance procedures are offered

  18. Instrumentalization of eating improves weight loss maintenance in obesity

    DEFF Research Database (Denmark)

    Christensen, Bodil Just; Iepsen, Eva Pers Winning; Lundgren, Julie Rehné

    2017-01-01

    Aim: The purpose of this study was to identify psychosocial determinants for maintaining weight loss. Methods: 42 obese individuals who achieved a 12% weight loss before entering a 52-week weight maintenance program were interviewed qualitatively. Psychosocial factors related to weight loss...... weight loss maintenance was associated with an interplay between behavioral, affective and contextual changes. ‘Instrumentalization of eating behavior' seems to be an important element in long-term weight maintenance....

  19. Human factor analysis and preventive countermeasures of maintenance in nuclear power plant

    International Nuclear Information System (INIS)

    Zhang Li; Hu Chao

    2008-01-01

    Based on the human error analysis theory and the characteristics of maintenance in a nuclear power plant, human factors of maintenance in NPP are divided into three different areas: human, technology, and organization, in which human refers to the individual factors, mainly including psychological quality, physiological characteristic, state of health, knowledge, skill level, and interpersonal relationship. Technology includes the maintenance technology, maintenance strategy, maintenance tool, maintenance interface, maintenance regulation, and work environment. Organization includes task arrangement, information communication, training, personnel external environment, team construction, and leadership. The analysis also reveals that the organization factors, which can indirectly influence personnel performance, are the primary initiators of human error. Based on these, some countermeasures are brought forward in order to reduce human errors. (authors)

  20. Human temporal cortical single neuron activity during working memory maintenance.

    Science.gov (United States)

    Zamora, Leona; Corina, David; Ojemann, George

    2016-06-01

    The Working Memory model of human memory, first introduced by Baddeley and Hitch (1974), has been one of the most influential psychological constructs in cognitive psychology and human neuroscience. However the neuronal correlates of core components of this model have yet to be fully elucidated. Here we present data from two studies where human temporal cortical single neuron activity was recorded during tasks differentially affecting the maintenance component of verbal working memory. In Study One we vary the presence or absence of distracting items for the entire period of memory storage. In Study Two we vary the duration of storage so that distractors filled all, or only one-third of the time the memory was stored. Extracellular single neuron recordings were obtained from 36 subjects undergoing awake temporal lobe resections for epilepsy, 25 in Study one, 11 in Study two. Recordings were obtained from a total of 166 lateral temporal cortex neurons during performance of one of these two tasks, 86 study one, 80 study two. Significant changes in activity with distractor manipulation were present in 74 of these neurons (45%), 38 Study one, 36 Study two. In 48 (65%) of those there was increased activity during the period when distracting items were absent, 26 Study One, 22 Study Two. The magnitude of this increase was greater for Study One, 47.6%, than Study Two, 8.1%, paralleling the reduction in memory errors in the absence of distracters, for Study One of 70.3%, Study Two 26.3% These findings establish that human lateral temporal cortex is part of the neural system for working memory, with activity during maintenance of that memory that parallels performance, suggesting it represents active rehearsal. In 31 of these neurons (65%) this activity was an extension of that during working memory encoding that differed significantly from the neural processes recorded during overt and silent language tasks without a recent memory component, 17 Study one, 14 Study two

  1. Human Temporal Cortical Single Neuron Activity During Working Memory Maintenance

    Science.gov (United States)

    Zamora, Leona; Corina, David; Ojemann, George

    2016-01-01

    The Working Memory model of human memory, first introduced by Baddeley and Hitch (1974), has been one of the most influential psychological constructs in cognitive psychology and human neuroscience. However the neuronal correlates of core components of this model have yet to be fully elucidated. Here we present data from two studies where human temporal cortical single neuron activity was recorded during tasks differentially affecting the maintenance component of verbal working memory. In Study One we vary the presence or absence of distracting items for the entire period of memory storage. In Study Two we vary the duration of storage so that distractors filled all, or only one-third of the time the memory was stored. Extracellular single neuron recordings were obtained from 36 subjects undergoing awake temporal lobe resections for epilepsy, 25 in Study one, 11 in Study two. Recordings were obtained from a total of 166 lateral temporal cortex neurons during performance of one of these two tasks, 86 study one, 80 study two. Significant changes in activity with distractor manipulation were present in 74 of these neurons (45%), 38 Study one, 36 Study two. In 48 (65%) of those there was increased activity during the period when distracting items were absent, 26 Study One, 22 Study Two. The magnitude of this increase was greater for Study One, 47.6%, than Study Two, 8.1%, paralleling the reduction in memory errors in the absence of distracters, for Study One of 70.3%, Study Two 26.3% These findings establish that human lateral temporal cortex is part of the neural system for working memory, with activity during maintenance of that memory that parallels performance, suggesting it represents active rehearsal. In 31 of these neurons (65%) this activity was an extension of that during working memory encoding that differed significantly from the neural processes recorded during overt and silent language tasks without a recent memory component, 17 Study one, 14 Study two

  2. Analysis of human-in-the-loop tele-operated maintenance inspection tasks using VR

    International Nuclear Information System (INIS)

    Boessenkool, H.; Abbink, D.A.; Heemskerk, C.J.M.; Steinbuch, M.; Baar, M.R. de; Wildenbeest, J.G.W.; Ronden, D.; Koning, J.F.

    2013-01-01

    Highlights: ► Execution of tele-operated inspection tasks for ITER maintenance was analyzed. ► Human factors experiments using Virtual Reality showed to be a valuable approach. ► A large variation in time performance and number of collisions was found. ► Results indicate significant room for improvement for teleoperated free space tasks. ► A promising solution is haptic shared control: assist operator with guiding forces. -- Abstract: One of the challenges in future fusion plants such as ITER is the remote maintenance of the plant. Foreseen human-in-the-loop tele-operation is characterized by limited visual and haptic feedback from the environment, which results in degraded task performance and increased operator workload. For improved tele-operated task performance it is required to get insight in the expected tasks and problems during maintenance at ITER. By means of an exploratory human factor experiment, this paper analyses problems and bottlenecks during the execution of foreseen tele-operated maintenance at ITER, identifying most promising areas of improvement. The focus of this paper is on free space (sub)tasks where contact with the environment needs to be avoided. A group of 5 subjects was asked to carry-out an ITER related free space task (visual inspection), using a six degree of freedom master device connected to a simulated hot cell environment. The results show large variation in time performance between subjects and an increasing number of collisions for more difficult tasks, indicating room for improvement for free space (sub)tasks. The results will be used in future research on the haptic guidance strategies in the ITER Remote Handling framework

  3. Analysis of human-in-the-loop tele-operated maintenance inspection tasks using VR

    Energy Technology Data Exchange (ETDEWEB)

    Boessenkool, H., E-mail: h.boessenkool@differ.nl [FOM Institute DIFFER (Dutch Institute for Fundamental Energy Research), Association EURATOM-FOM, Partner in the Trilateral Euregio Cluster, PO Box 1207, 3430 BE Nieuwegein (Netherlands); Eindhoven University of Technology, Department of Mechanical Engineering, Dynamics and Control Group, PO Box 513, 5600 MB Eindhoven (Netherlands); Abbink, D.A. [Delft University of Technology, Faculty of 3mE, BioMechanical Engineering Department, Mekelweg 2, 2628 CD Delft (Netherlands); Heemskerk, C.J.M. [Heemskerk Innovative Technology B.V., Jonckerweg 12, 2201 DZ Noordwijk (Netherlands); Steinbuch, M. [Eindhoven University of Technology, Department of Mechanical Engineering, Dynamics and Control Group, PO Box 513, 5600 MB Eindhoven (Netherlands); Baar, M.R. de [FOM Institute DIFFER (Dutch Institute for Fundamental Energy Research), Association EURATOM-FOM, Partner in the Trilateral Euregio Cluster, PO Box 1207, 3430 BE Nieuwegein (Netherlands); Eindhoven University of Technology, Department of Mechanical Engineering, Dynamics and Control Group, PO Box 513, 5600 MB Eindhoven (Netherlands); Wildenbeest, J.G.W. [Delft University of Technology, Faculty of 3mE, BioMechanical Engineering Department, Mekelweg 2, 2628 CD Delft (Netherlands); Heemskerk Innovative Technology B.V., Jonckerweg 12, 2201 DZ Noordwijk (Netherlands); Ronden, D. [FOM Institute DIFFER (Dutch Institute for Fundamental Energy Research), Association EURATOM-FOM, Partner in the Trilateral Euregio Cluster, PO Box 1207, 3430 BE Nieuwegein (Netherlands); Koning, J.F. [Heemskerk Innovative Technology B.V., Jonckerweg 12, 2201 DZ Noordwijk (Netherlands)

    2013-10-15

    Highlights: ► Execution of tele-operated inspection tasks for ITER maintenance was analyzed. ► Human factors experiments using Virtual Reality showed to be a valuable approach. ► A large variation in time performance and number of collisions was found. ► Results indicate significant room for improvement for teleoperated free space tasks. ► A promising solution is haptic shared control: assist operator with guiding forces. -- Abstract: One of the challenges in future fusion plants such as ITER is the remote maintenance of the plant. Foreseen human-in-the-loop tele-operation is characterized by limited visual and haptic feedback from the environment, which results in degraded task performance and increased operator workload. For improved tele-operated task performance it is required to get insight in the expected tasks and problems during maintenance at ITER. By means of an exploratory human factor experiment, this paper analyses problems and bottlenecks during the execution of foreseen tele-operated maintenance at ITER, identifying most promising areas of improvement. The focus of this paper is on free space (sub)tasks where contact with the environment needs to be avoided. A group of 5 subjects was asked to carry-out an ITER related free space task (visual inspection), using a six degree of freedom master device connected to a simulated hot cell environment. The results show large variation in time performance between subjects and an increasing number of collisions for more difficult tasks, indicating room for improvement for free space (sub)tasks. The results will be used in future research on the haptic guidance strategies in the ITER Remote Handling framework.

  4. Improvement of the M/S manipulator maintenance at OSL

    International Nuclear Information System (INIS)

    Kuwana, Koichi; Ouchi, Hiroshi; Ito, Yutaka; Sato, Yoshihiro; Midorikawa, Mituhiro; Hayakawa, Tuyoshi

    2010-01-01

    The safeguards inspection samples from the JNFL Rokkasho Reprocessing Plant (RRP) are received and analyzed at the On Site Laboratory (OSL). Since the samples from the input accountancy tank of the RRP contain a lot of fission products, they are treated in a hot-cell line with a M/S (Master /Slave) manipulator. Special equipment and tools were used for the maintenance of the M/S manipulator, especially for the exchange of the M/S manipulator. However, the manipulator exchange work was not easy due to the limitation of the space in the OSL. For solution to this problem, a monorail and monorail hoist equipment was installed onto wall surface of analytical room close to each M/S manipulator, and then it made the exchange of M/S manipulator easy without special equipment and tools. Additionally, operator was freed from the burden of working space arranging for the exchange of M/S manipulator such as removing of analytical equipments. This report represents the improvement of operation for the exchange of M/S manipulator with installation of monorail and hoist equipment. (author)

  5. PSA Model Improvement Using Maintenance Rule Function Mapping

    Energy Technology Data Exchange (ETDEWEB)

    Seo, Mi Ro [KHNP-CRI, Nuclear Safety Laboratory, Daejeon (Korea, Republic of)

    2011-10-15

    The Maintenance Rule (MR) program, in nature, is a performance-based program. Therefore, the risk information derived from the Probabilistic Safety Assessment model is introduced into the MR program during the Safety Significance determination and Performance Criteria selection processes. However, this process also facilitates the determination of the vulnerabilities in currently utilized PSA models and offers means of improving them. To find vulnerabilities in an existing PSA model, an initial review determines whether the safety-related MR functions are included in the PSA model. Because safety-related MR functions are related to accident prevention and mitigation, it is generally necessary for them to be included in the PSA model. In the process of determining the safety significance of each functions, quantitative risk importance levels are determined through a process known as PSA model basic event mapping to MR functions. During this process, it is common for some inadequate and overlooked models to be uncovered. In this paper, the PSA model and the MR program of Wolsong Unit 1 were used as references

  6. Summary of EPRI projects for improving power plant maintenance and maintainability

    International Nuclear Information System (INIS)

    Shugars, H.G.; Poole, D.N.; Pack, R.W.

    1979-01-01

    The Electric Power Research Institute is sponsoring projects to improve power plant maintenance and maintainability. Areas presently being emphasized are improvements in plant design for maintainability, improvements in performing nuclear plant refuelings, and development of on-line monitoring and diagnostic systems for various plant components. The seven projects are reviewed. They are: (1) human factors review of power plant maintainability; (2) refueling outage improvement; (3) on-line monitoring and diagnostics for power plant machinery; (4) acoustic emission and vibrati1on signature analysis of fossil fuel plant components; (5) acoustic monitoring of power plant valves; (6) on-line monitoring and diagnostics for generators; and (7) detection of water induction in steam turbines. Each project contractor and the project manager are listed for reference. 8 references

  7. ATP economy of force maintenance in human tibialis anterior muscle

    DEFF Research Database (Denmark)

    Nakagawa, Yoshinao; Ratkevicius, Aivaras; Mizuno, Masao

    2005-01-01

    PURPOSE: The aim of this study was investigate ATP economy of force maintenance in the human tibialis anterior muscle during 60 s of anaerobic voluntary contraction at 50% of maximum voluntary contraction (MVC). METHODS: ATP turnover rate was evaluated using P magnetic resonance spectroscopy (P...... contraction. It averaged at 4.81 +/- 0.42 N.s.micromol-1, and correlated with the relative cross-sectional area of the muscle occupied by Type I fiber (r = 0.73, P contraction, subjects dropping in force showed lower ATP economy compared with those maintaining the force (3.......7 +/- 0.6 vs 5.3 +/- 0.6 N.s.micromol-1; P contraction could be due to an increase in the ATP economy of contracting muscle fibers offsetting the effects of increased temperature and low ATP economy...

  8. Equipment reliability process improvement and preventive maintenance optimization

    International Nuclear Information System (INIS)

    Darragi, M.; Georges, A.; Vaillancourt, R.; Komljenovic, D.; Croteau, M.

    2004-01-01

    The Gentilly-2 Nuclear Power Plant wants to optimize its preventive maintenance program through an Integrated Equipment Reliability Process. All equipment reliability related activities should be reviewed and optimized in a systematic approach especially for aging plants such as G2. This new approach has to be founded on best practices methods with the purpose of the rationalization of the preventive maintenance program and the performance monitoring of on-site systems, structures and components (SSC). A rational preventive maintenance strategy is based on optimized task scopes and frequencies depending on their applicability, critical effects on system safety and plant availability as well as cost-effectiveness. Preventive maintenance strategy efficiency is systematically monitored through degradation indicators. (author)

  9. Improved Navy Maintenance Through Corrosion-Fatigue Assessment Program

    National Research Council Canada - National Science Library

    Hoppe, Wally

    2008-01-01

    ... to evaluate issues relevant to corrosion-fatigue of aircraft components. In this multi-year, multi-contract program, tools have been developed to assist in the establishment of maintenance options for corroded components...

  10. Improvement of the availability of nuclear power station maintenance teleprocessing

    International Nuclear Information System (INIS)

    Badellon, D.; Bloton, Y.; Bres, J.P.; Cuche, A.; Trabaud, C.

    1993-11-01

    The Data processing department at the DEPT manages a centralized maintenance application for the nineteen power plants in France. This application performs fourteen million CICS transactions every month, passing through the Electricite de France national teleprocessing network. Operation is split among two IBM 9021 computer partitions located one hundred kilometres apart for backup and security reasons in the two computer centres of the STI (EDF Data Processing Department) and the R and DD (EDF Research and Development Department). The CICS are stopped each night at 10.30 so that the data bases can be backed up onto cassettes and so that the work from the plants can be processed in batches. The plants update the number of bases and extract subsets intended for the plants. From the outset, considerable resources were assigned to this operation: cassette insertion robots, a high-power batch processing scheduling and planning tool optimizing parallel step work, high-power computers: two IBM 3090-40J computers were dedicated to this application as early as 1989. However, the buildup and evolution of this application led to ever greater basic volumes and increasingly voluminous and complex batch processing, leading to reduced transactional availability by pushing back the startup times. To combat this trend, the Data Processing Department at the DEPT, together with the Departments operating the computers, took a number of steps to speed up batch processing and thus improve teleprocessing availability. In particular, on the partition operated by the computer Centre in the Applied Mathematics and Data Processing Service of the Research and Development Department at EDF, a number of studies were conducted, as described in the following text. This description comprises three parts: - report on the studies and steps taken, both from the hardware and the software viewpoint; - an evaluation of their effectiveness and the results obtained; - the new areas for study selected

  11. Instrumentalization of Eating Improves Weight Loss Maintenance in Obesity

    Directory of Open Access Journals (Sweden)

    Bodil Just Christensen

    2017-12-01

    Full Text Available Aim: The purpose of this study was to identify psychosocial determinants for maintaining weight loss. Methods: 42 obese individuals who achieved a 12% weight loss before entering a 52-week weight maintenance program were interviewed qualitatively. Psychosocial factors related to weight loss maintenance were identified in two contrasting groups: weight reducers and weight regainers. Groups were defined by health-relevant weight maintenance (additional weight loss > 3% at week 52, n = 9 versus weight gain > 3%, at week 52, n = 20. Results: Weight reducers reported structured meal patterns (p = 0.008, no comfort eating (p = 0.016 and less psychosocial stress (p = 0.04 compared to weight regainers. The ability to instrumentalize eating behavior emerged as an important factor (p = 0.007. Nutritional knowledge, motivation or exercise level did not differ between groups (p > 0.05. Conclusions: Successful weight loss maintenance was associated with an interplay between behavioral, affective and contextual changes. ‘Instrumentalization of eating behavior' seems to be an important element in long-term weight maintenance.

  12. Improving Maintenance Data Collection Via Point-Of-Maintenance (POMX) Implementation

    Science.gov (United States)

    2006-03-01

    accurate documentation, (3) identifying and correcting the root causes for poor data integrity, and (4) educating the unit on the critical need for data ...the validity of the results. The data in this study were analyzed using the SAS JMP 6.0 statistical software package. The results for the tests...traditional keyboard data entry methods at a computer terminal. These terminals are typically located in the aircraft maintenance unit (AMU) facility , away

  13. A Study on Human Factors in Maintenance of a Nuclear Power Plant (NPP)

    International Nuclear Information System (INIS)

    Park, Young Ho; Seong, Poong Hyun

    2006-01-01

    In human factors research, more attention has been devoted to the operation of a nuclear power plant (NPP) than to their maintenance. However, more NPP incidents are caused by inadequate maintenance rather than by faulty operation. There is a trend in NPP toward introducing digital technology into safety and non-safety systems. This lead to changes of maintenance, and support systems such as diagnosis system, augmentation system and handy terminal will be developed. In this context, it is important to identify tasks of human related to each phase of maintenance and their relation in order to apply those to maintenance. However, there are few researches of human factors in maintenance. This paper studies on framework of cognitive task analysis for developing maintenance support systems

  14. Human Resources Training Requirement on NPP Operation and Maintenance

    International Nuclear Information System (INIS)

    Nurlaila; Yuliastuti

    2009-01-01

    This paper discussed the human resources requirement on Nuclear Power Plant (NPP) operation and maintenance (O&M) phase related with the training required for O&M personnel. In addition, this paper also briefly discussed the availability of training facilities domestically include with some suggestion to develop the training facilities intended for the near future time in Indonesia. This paper was developed under the assumptions that Indonesia will build twin unit of NPP with capacity 1000 MWe for each using the turnkey contract method. The total of NPP O&M personnel were predicted about 692 peoples which consists of 42 personnel located in the head quarter and the rest 650 people work at NPP site. Up until now, Indonesia had the experience on operating and maintaining the nonnuclear power plant and several research reactors namely Kartini Reactor Yogyakarta, Triga Mark II Reactor Bandung, and GA Siwabessy Reactor Serpong. Beside that, experience on operating and maintaining the NPP in other countries would act as one of the reference to Indonesia in formulating an appropriate strategy to develop NPP human resources particularly in O&M phases. Education and training development program could be done trough the cooperation with vendor candidates. (author)

  15. PROBING GENOME MAINTENANCE FUNCTIONS OF HUMAN RECQ1

    Directory of Open Access Journals (Sweden)

    Furqan Sami

    2013-03-01

    Full Text Available The RecQ helicases are a highly conserved family of DNA-unwinding enzymes that play key roles in protecting the genome stability in all kingdoms of life.'Human RecQ homologs include RECQ1, BLM, WRN, RECQ4, and RECQ5β.'Although the individual RecQ-related diseases are characterized by a variety of clinical features encompassing growth defects (Bloom Syndrome and Rothmund Thomson Syndrome to premature aging (Werner Syndrome, all these patients have a high risk of cancer predisposition.'Here, we present an overview of recent progress towards elucidating functions of RECQ1 helicase, the most abundant but poorly characterized RecQ homolog in humans.'Consistent with a conserved role in genome stability maintenance, deficiency of RECQ1 results in elevated frequency of spontaneous sister chromatid exchanges, chromosomal instability, increased DNA damage and greater sensitivity to certain genotoxic stress.'Delineating what aspects of RECQ1 catalytic functions contribute to the observed cellular phenotypes, and how this is regulated is critical to establish its biological functions in DNA metabolism.'Recent studies have identified functional specialization of RECQ1 in DNA repair; however, identification of fundamental similarities will be just as critical in developing a unifying theme for RecQ actions, allowing the functions revealed from studying one homolog to be extrapolated and generalized to other RecQ homologs.

  16. Information Management System Development for the Characterization and Analysis of Human Error in Naval Aviation Maintenance Related Mishaps

    National Research Council Canada - National Science Library

    Wood, Brian

    2000-01-01

    .... The Human Factors Analysis and Classification System-Maintenance Extension taxonomy, an effective framework for classifying and analyzing the presence of maintenance errors that lead to mishaps...

  17. UNC Nuclear Industries' human-factored approach to the operating or maintenance procedure

    International Nuclear Information System (INIS)

    Nelson, A.A.; Clark, J.E.

    1982-01-01

    The development of Human Factors Engineering (HFE) and UNC Nuclear Industries' (UNC) commitment to minimizing the potential for human error in the performance of operating or maintenance procedures have lead to a procedure upgrade program. Human-factored procedures were developed using information from many sources including, but not limited to, operators, a human factors specialist, engineers and supervisors. This has resulted in the Job Performance Aid (JPA). This paper presents UNC's approach to providing human-factored operating and maintenance procedures

  18. Ballistic characteristics improving and maintenance of protective ballistic vests

    OpenAIRE

    RADONJIC VOJKAN M.; JOVANOVIC DANKO M.; ZIVANOVIC GORAN Z.; RESIMIC BRANKO V.

    2014-01-01

    The work presents research of the materials necessary for the maintenance of protective ballistic vests. In this paper is proposed a new construction design with modern materials for ballistic inserts producing. This paper also presents the results of laboratory tests of ballistic cartridges with new materials. Based on the test results, it can be concluded, the proposed technical solution for making ballistic inserts adequately meets current standards.

  19. Use of passive systems to improve plant operation and maintenance

    International Nuclear Information System (INIS)

    Shah, D.

    2000-01-01

    In a deregulated future, a utility's strength will depend on its ability to be cost competitive in the marketplace. However, the competitive advantage of nuclear power will depend on each owner's ability to reduce Operating and Maintenance (O and M) costs without sacrificing nuclear safety. The use of passive systems (i.e., systems without any moving parts) can reduce plant O and M costs while increasing safety in nuclear power plants. (author)

  20. Research on operation and maintenance support system adaptive to human recognition and understanding in human-centered plant

    International Nuclear Information System (INIS)

    Numano, Masayoshi; Matsuoka, Takeshi; Mitomo, N.

    2004-01-01

    As a human-centered plant, advanced nuclear power plant needs appropriate role sharing between human and mobile intelligent agents. Human-machine cooperation for plant operation and maintenance activities is also required with an advanced interface. Plant's maintenance is programmed using mobile robots working under the radiation environments instead of human beings. Operation and maintenance support system adaptive to human recognition and understanding should be developed to establish adequate human and machine interface so as to induce human capabilities to the full and enable human to take responsibility for plan's operation. Plant's operation and maintenance can be cooperative activities between human and intelligent automonous agents having surveillance and control functions. Infrastructure of multi-agent simulation system for the support system has been investigated and developed based on work plans derived from the scheduler. (T. Tanaka)

  1. An analysis of human maintenance failures of a nuclear power plant

    International Nuclear Information System (INIS)

    Pyy, P.

    2000-01-01

    In the report, a study of faults caused by maintenance activities is presented. The objective of the study was to draw conclusions on the unplanned effects of maintenance on nuclear power plant safety and system availability. More than 4400 maintenance history reports from the years 1992-1994 of Olkiluoto BWR nuclear power plant (NPP) were analysed together with the maintenance personnel. The human action induced faults were classified, e.g., according to their multiplicity and effects. This paper presents and discusses the results of a statistical analysis of the data. Instrumentation and electrical components appeared to be especially prone to human failures. Many human failures were found in safety related systems. Several failures also remained latent from outages to power operation. However, the safety significance of failures was generally small. Modifications were an important source of multiple human failures. Plant maintenance data is a good source of human reliability data and it should be used more in the future. (orig.)

  2. Statistical analysis of human maintenance failures of a nuclear power plant

    International Nuclear Information System (INIS)

    Pyy, P.

    2000-01-01

    In this paper, a statistical study of faults caused by maintenance activities is presented. The objective of the study was to draw conclusions on the unplanned effects of maintenance on nuclear power plant safety and system availability. More than 4400 maintenance history reports from the years 1992-1994 of Olkiluoto BWR nuclear power plant (NPP) were analysed together with the maintenance personnel. The human action induced faults were classified, e.g., according to their multiplicity and effects. This paper presents and discusses the results of a statistical analysis of the data. Instrumentation and electrical components are especially prone to human failures. Many human failures were found in safety related systems. Similarly, several failures remained latent from outages to power operation. The safety significance was generally small. Modifications are an important source of multiple human failures. Plant maintenance data is a good source of human reliability data and it should be used more, in future. (orig.)

  3. Systematic analysis and prevention of human originated common cause failures in relation to maintenance activities at Finnish nuclear power plants

    Energy Technology Data Exchange (ETDEWEB)

    Laakso, K. [VTT Industrial Systems, Espoo (Finland)

    2006-12-15

    The focus in human reliability analysis of nuclear power plants has traditionally been on human performance in disturbance conditions. On the other hand, human maintenance failures and design deficiencies, remained latent in the system, have an impact on the severity of a disturbance, e.g. by disabling safety-related equipment on demand. Especially common cause failures (CCFs) of safety related systems can affect the core damage risk to a significant extent. The topic has been addressed in Finnish studies, where experiences of latent human errors have been searched and analysed systematically from the maintenance history stored in the the power plant information systems of the Loviisa and Olkiluoto NPPs. Both the single and multiple errors (CCFs) were classified in detail and documented as error and event reports. The human CCFs involved human, organisational and technical factors. The review of the analysed single and multiple errors showed that instrumentation and control and electrical equipment are more prone to human error caused failure events than the other maintenance objects. The review of the analysed experience showed that most errors stem from the refuelling and maintenance outage periods. More than half of the multiple errors from the outages remained latent to the power operating periods. The review of the analysed multiple errors showed that difficulties with small plant modifications and planning of maintenance and operability were significant sources of common cause failures. The most dependent human errors originating from small modifications could be reduced by a more tailored planning and coverage of their start-up testing programs. Improvements could also be achieved by identifying better in work planning from the operating experiences those complex or intrusive repair and preventive maintenance work tasks and actions which are prone to errors. Such uncertain cases in important equipment require a more tailored work planning of the installation

  4. Systematic analysis and prevention of human originated common cause failures in relation to maintenance activities at Finnish nuclear power plants

    International Nuclear Information System (INIS)

    Laakso, K.

    2006-12-01

    The focus in human reliability analysis of nuclear power plants has traditionally been on human performance in disturbance conditions. On the other hand, human maintenance failures and design deficiencies, remained latent in the system, have an impact on the severity of a disturbance, e.g. by disabling safety-related equipment on demand. Especially common cause failures (CCFs) of safety related systems can affect the core damage risk to a significant extent. The topic has been addressed in Finnish studies, where experiences of latent human errors have been searched and analysed systematically from the maintenance history stored in the the power plant information systems of the Loviisa and Olkiluoto NPPs. Both the single and multiple errors (CCFs) were classified in detail and documented as error and event reports. The human CCFs involved human, organisational and technical factors. The review of the analysed single and multiple errors showed that instrumentation and control and electrical equipment are more prone to human error caused failure events than the other maintenance objects. The review of the analysed experience showed that most errors stem from the refuelling and maintenance outage periods. More than half of the multiple errors from the outages remained latent to the power operating periods. The review of the analysed multiple errors showed that difficulties with small plant modifications and planning of maintenance and operability were significant sources of common cause failures. The most dependent human errors originating from small modifications could be reduced by a more tailored planning and coverage of their start-up testing programs. Improvements could also be achieved by identifying better in work planning from the operating experiences those complex or intrusive repair and preventive maintenance work tasks and actions which are prone to errors. Such uncertain cases in important equipment require a more tailored work planning of the installation

  5. Can training improve human performance

    International Nuclear Information System (INIS)

    Waylett, W.J. Jr.

    1986-01-01

    The nuclear industry has made a significant commitment to improve training through the implementation of performance-based training programs. Senior management expects that human performance improvement will result from this significant resource allocation. The author examines this hypothesis and discusses other issues that may interfere with enhancing human performance through training. The integration of quality improvement concepts to support training is also discussed by the author, who was a pioneer facilitator during the development of Florida Power and Light Company's Quality Improvement Program. Critical success factors are proposed based on the author's experience as a plant manager, training manager and quality facilitator

  6. Competence within Maintenance

    OpenAIRE

    Nerland, Annette Smørholm

    2010-01-01

    Maintenance can be a contributing factor to unwanted events, as well as desired events and states. Human competence can be defined as the ability to perform a specific task, action or function successfully, and is therefore a key factor to proper execution of maintenance tasks. Hence,maintenance will have negative consequences if done wrong, and give positive results when done right. The purpose of this report is to study the many aspects of maintenance competence. Endeavoring to improve ...

  7. Human Error Probability Assessment During Maintenance Activities of Marine Systems

    OpenAIRE

    Rabiul Islam; Faisal Khan; Rouzbeh Abbassi; Vikram Garaniya

    2018-01-01

    Background: Maintenance operations on-board ships are highly demanding. Maintenance operations are intensive activities requiring high man–machine interactions in challenging and evolving conditions. The evolving conditions are weather conditions, workplace temperature, ship motion, noise and vibration, and workload and stress. For example, extreme weather condition affects seafarers' performance, increasing the chances of error, and, consequently, can cause injuries or fatalities to personne...

  8. Engine health monitoring systems: Tools for improved maintenance management in the 1980's

    Science.gov (United States)

    Kimball, J. C.

    1981-01-01

    The performance monitoring aspect of maintenance, characteristic of the engine health monitoring system are discussed. An overview of the system activities is presented and a summary of programs for improved monitoring in the 1980's are discussed.

  9. Environmental Assessment for Waterfront Facilities Maintenance and Improvements, Pearl Harbor Naval Complex, Oahu, Hawaii

    National Research Council Canada - National Science Library

    2005-01-01

    Commander, Navy Region Hawaii (CNRH) proposes to repair, maintain, and improve waterfront berthing and maintenance facilities for ships and submarines on an as-needed basis within the Pearl Harbor Naval Complex (PHNC...

  10. Human factors in operational maintenance on future naval vessels

    NARCIS (Netherlands)

    Post, W.M.; Schreurs, J.C.; Rakhorst-Oudendijk, M.L.W.; Badon Ghijben, N.A.; Diggelen, J. van

    2014-01-01

    The increasing complexity of operational maintenance on naval platforms and the need to sustain this also in battle conditions are in conflict with the requirement for crew reduction. This asks for a new approach. The Netherlands MoD knows how to develop technical solutions for operational

  11. Maintenance of hyperglycaemia does not improve performance in a ...

    African Journals Online (AJOL)

    a glucose clamp, improves 100 km cycling time-trial (TT) performance. Design. .... each TT, subjects were permitted to ingest water ad libitum. statistical .... The effects of normal and glucose syrup work diets on the ... Fructose and glucose ...

  12. Human factors issues in aircraft maintenance and inspection : "information exchange and communications".

    Science.gov (United States)

    1990-11-01

    The Federal Aviation Administration sponsored a 2-day meeting in December 1989 as part of a continuing program to address issues of human factors and personnel performance in aviation maintenance and inspection. This meeting focused on issues of "inf...

  13. Improvement of the preventive maintenance program of an emergency diesel generator set

    International Nuclear Information System (INIS)

    Jacquot, J.P.; Meuwisse, C.; Cailleaux, J.P.

    1995-01-01

    An exhaustive Reliability Centered Maintenance (RCM) analysis was performed of the emergency diesel generator sets in Electricite de France 900-MW nuclear power plants. The first part of this paper describes the Reliability Centered Maintenance approach, including the functional breakdown, complete analysis of operation feedback and safety assessment of the risk induced by functional diesel failures. The second part shows how this kind of RCM analysis can be used to improve the efficiency of periodic tests of the machine, and more generally, the efficiency of condition-directed maintenance tasks. The underlying objective is to minimize risk and aging of the machine

  14. Operation, maintenance and improvements of the ALS. Chapter 3

    International Nuclear Information System (INIS)

    New amplitude modulating circuit for the injector is used with switched beams. New transistorized circuit for the transmitters is developed. Various improvements are made on HF measurements. Focusing and steering apparatus are improved. Description of the solution adopted for adjusting the beam at the new repetition rate of 6.17 Hz. A new 200 A fast switched supply is under construction. 1000 hours test has been made on the high power rotating target for the e - /e + converter. Studies for beam position monitors either with ferrites or with HF cavities are in progress. Sensitivity of the ferrite beam intensity monitors is now as good as 0.25 μA peak current. Vacuum and magnetic measurements are improved [fr

  15. 25 CFR 170.808 - Can BIA Road Maintenance Program funds be used to improve IRR transportation facilities?

    Science.gov (United States)

    2010-04-01

    ... 25 Indians 1 2010-04-01 2010-04-01 false Can BIA Road Maintenance Program funds be used to improve... THE INTERIOR LAND AND WATER INDIAN RESERVATION ROADS PROGRAM BIA Road Maintenance § 170.808 Can BIA Road Maintenance Program funds be used to improve IRR transportation facilities? No. BIA Road...

  16. Innovative predictive maintenance concepts to improve life cycle management

    NARCIS (Netherlands)

    Tinga, Tiedo

    2014-01-01

    For naval systems with typically long service lives, high sustainment costs and strict availability requirements, an effective and efficient life cycle management process is very important. In this paper four approaches are discussed to improve that process: physics of failure based predictive

  17. ISO 9000 and quality standards improvement in the maintenance ...

    African Journals Online (AJOL)

    This study investigated ISO 9000 as a tool for improving quality standards in ... The study used cross-sectional descriptive research design, using quantitative research ... enhance business performance and competiveness of manufacturing firms. ... By Country · List All Titles · Free To Read Titles This Journal is Open Access.

  18. AREVA NP products and services for NPP operation and maintenance improvement

    International Nuclear Information System (INIS)

    Dechelette, Anne; Rat, Guy Le

    2009-01-01

    AREVA supplies customized services throughout the reactor improvement process according to clients' requirements: safety, performance, availability, obsolescence, operating and maintenance conditions, environment and technical assistance. Form design studies to on site modification and implementation including requalification tests, AREVA, as OEM*, has various products and services in the field of Engineering and Upgrading to satisfy client demands. In keeping with Inpo's AP913 approach, AREVA is particularly skilled in this methodology to help utilities improve availability factor and maintenance programs. AREVA has customized its services to many utilities in cooperating with local partners, suppliers, and engineering service providers through partnerships, consortiums, joint ventures, etc. AREVA's knowledge of the fleet's operation and maintenance experience helps NPP clients to identify the most cost effective improvements and approaches. Different examples of modifications of modifications and improvements performed in France and abroad illustrate AREVA's involvement in the NPP continuous upgrade process

  19. Designing nuclear power plants for improved operation and maintenance

    International Nuclear Information System (INIS)

    1996-09-01

    The purpose of this publication is to compile demonstrated, experience based design guidelines for improving the operability and maintainability of nuclear power plants. The guidelines are for use principally in the design of new nuclear power plants, but should also be useful in upgrading existing designs. The guidelines derive from the experience of operating and maintaining existing nuclear power plants as well as from the design of recent plants. In particular these guidelines are based on and consistent with both the EPRI advanced Light Water Reactor Utility Requirements Document, Volume 1, and the European Utility Requirements for LWR Nuclear Power Plants. 6 refs, 1 fig

  20. Designing nuclear power plants for improved operation and maintenance

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1996-09-01

    The purpose of this publication is to compile demonstrated, experience based design guidelines for improving the operability and maintainability of nuclear power plants. The guidelines are for use principally in the design of new nuclear power plants, but should also be useful in upgrading existing designs. The guidelines derive from the experience of operating and maintaining existing nuclear power plants as well as from the design of recent plants. In particular these guidelines are based on and consistent with both the EPRI advanced Light Water Reactor Utility Requirements Document, Volume 1, and the European Utility Requirements for LWR Nuclear Power Plants. 6 refs, 1 fig.

  1. A Simulation Model for Machine Efficiency Improvement Using Reliability Centered Maintenance: Case Study of Semiconductor Factory

    Directory of Open Access Journals (Sweden)

    Srisawat Supsomboon

    2014-01-01

    Full Text Available The purpose of this study was to increase the quality of product by focusing on the machine efficiency improvement. The principle of the reliability centered maintenance (RCM was applied to increase the machine reliability. The objective was to create preventive maintenance plan under reliability centered maintenance method and to reduce defects. The study target was set to reduce the Lead PPM for a test machine by simulating the proposed preventive maintenance plan. The simulation optimization approach based on evolutionary algorithms was employed for the preventive maintenance technique selection process to select the PM interval that gave the best total cost and Lead PPM values. The research methodology includes procedures such as following the priority of critical components in test machine, analyzing the damage and risk level by using Failure Mode and Effects Analysis (FMEA, calculating the suitable replacement period through reliability estimation, and optimizing the preventive maintenance plan. From the result of the study it is shown that the Lead PPM of test machine can be reduced. The cost of preventive maintenance, cost of good product, and cost of lost product were decreased.

  2. Task analysis of human-in-the-loop tele-operated maintenance: What can be learned from JET?

    International Nuclear Information System (INIS)

    Boessenkool, H.; Thomas, J.; Heemskerk, C.J.M.; Baar, M.R. de; Steinbuch, M.; Abbink, D.A.

    2014-01-01

    Highlights: •Maintenance task execution at JET was analyzed to guide improvements for ITER. •A large variation in task duration was found for various operator experience levels. •Results indicate significant room for improvement for tele-operated performance. •Improvent of visual feedback and artificial guiding forces was considered promising. -- Abstract: Remote maintenance will determine the available uptime of future fusion plants such as ITER. Experience at predecessor JET showed that a human-in-the-loop tele-operated approach is crucial, although this approach entails drawbacks such as the unavoidable extensive operator training and relatively long execution times. These drawbacks are common knowledge, but little quantitative research is available to guide improvements (such as improved training methods, or active operator support systems). The aim of this paper is to identify the key areas for further improvement of tele-operated maintenance. This is achieved by a detailed task analysis based on recent maintenance at JET, using task logbooks and video data as well as interviews with experienced master–slave operators. The resulting task analysis shows the (sub)tasks that were most time-consuming and shows a large variance in time performance within operators, but also substantial differences between qualified operators with different levels of experience. The operator interviews indicate that intuitive (virtual) visual feedback and artificial (guiding) forces are promising directions for improvement. The results found in this study will be used for future research and development activities focusing on haptic guiding strategies, with the aim to further design and optimize RH maintenance systems for ITER and beyond

  3. Industry assessment of human factors in aviation maintenance and inspection research program : an assessment of industry awareness and use of the Federal Aviation Administration Office of Aviation Medicine Human Factors in Aviation Maintenance and Inspect

    Science.gov (United States)

    1998-03-01

    Ten years ago the Federal Aviation Administration (FAA) Office of Aviation Medicine embarked on a research and development program dedicated to human factors in aviation maintenance and inspection. Since 1989 FAA has invested over $12M in maintenance...

  4. Long-term maintenance of human induced pluripotent stem cells by automated cell culture system.

    Science.gov (United States)

    Konagaya, Shuhei; Ando, Takeshi; Yamauchi, Toshiaki; Suemori, Hirofumi; Iwata, Hiroo

    2015-11-17

    Pluripotent stem cells, such as embryonic stem cells and induced pluripotent stem (iPS) cells, are regarded as new sources for cell replacement therapy. These cells can unlimitedly expand under undifferentiated conditions and be differentiated into multiple cell types. Automated culture systems enable the large-scale production of cells. In addition to reducing the time and effort of researchers, an automated culture system improves the reproducibility of cell cultures. In the present study, we newly designed a fully automated cell culture system for human iPS maintenance. Using an automated culture system, hiPS cells maintained their undifferentiated state for 60 days. Automatically prepared hiPS cells had a potency of differentiation into three germ layer cells including dopaminergic neurons and pancreatic cells.

  5. Different genome maintenance strategies in human and tobacco cells.

    Science.gov (United States)

    Pelczar, Pawel; Kalck, Véronique; Kovalchuk, Igor

    2003-08-22

    In this work, genome maintenance strategies of organisms belonging to different kingdoms (animals versus plants) but of similar genome size were investigated using a novel, universal double-strand break (DSB) repair assay. Different plasmids linearised with KpnI, Acc65I or EcoRV yielding either 3' or 5' protruding or blunt DNA termini, respectively, were transfected into HeLa cells and Nicotiana plumbaginifolia protoplasts and assayed for the efficiency and fidelity of DSB repair. We show that the mechanism of break sealing is similar but that drastic differences are seen in the fidelity of repair: in HeLa cells, 50-55% DSBs were repaired precisely, compared to as little as 15-30% in tobacco cells. Moreover, the DSB repair in plants resulted in 30-40% longer deletions and significantly shorter insertions. Combined, these led to more than twofold larger net DNA loss in tobacco cells. Our observations point to possible differences in the strategies of DSB repair and genome maintenance in plants and animals.

  6. Towards Improved Human Resource Development In Nigeria ...

    African Journals Online (AJOL)

    Towards Improved Human Resource Development In Nigeria: Challenges And Prospects. ... Journal of Research in National Development ... Consequently, the paper recommended; improved investment in education, implementable policies on human resource development, involvement of private organization in human ...

  7. Web-Based Information Management System for the Investigation, Reporting, and Analysis of Human Error in Naval Aviation Maintenance

    National Research Council Canada - National Science Library

    Boex, Anthony

    2001-01-01

    .... The Human Factors Analysis and Classification System-Maintenance Extension (HFACS-ME) taxonomy, a framework for classifying and analyzing the presence of maintenance errors that lead to mishaps, is the foundation of this tool...

  8. Human Reliability Analysis. Applicability of the HRA-concept in maintenance shutdown

    International Nuclear Information System (INIS)

    Obenius, Aino

    2007-08-01

    Probabilistic Safety Analysis (PSA) is performed for Swedish nuclear power plants in order to make predictions and improvements of system safety. The analysis of the Three Mile Island and Chernobyl accidents contributed to broaden the approach to nuclear power plant safety. A system perspective focusing on the interaction between aspects of Man, Technology and Organization (MTO) emerged in addition to the development of Human Factors knowledge. To take the human influence on the technical system into consideration when performing PSAs, a Human Reliability Analysis (HRA) is performed. PSA is performed for different stages and plant operating states, and the current state of Swedish analyses is Low power and Shutdown (LPSD), also called Shutdown PSA (SPSA). The purpose of this master's thesis is to describe methods and basic models used when analysing human reliability for the LPSD state. The following questions are at issue: 1. How can the LPSD state be characterised and defined? 2. What is important to take into consideration when performing a LPSD HRA? 3. How can human behaviour be modelled for a LPSD risk analysis? 4. According to available empirical material, how are the questions above treated in performed analysis of human operation during LPSD? 5. How does the result of the questions above affect the way methods for analysis of LPSD could and/or should be developed? The procedure of this project has mainly consisted of literature studies of available theory for modelling of human behaviour and risk analysis of the LPSD state. This study regards analysis of planned outages when maintenance, fuel change, tests and inspections are performed. The outage period is characterised by planned maintenance activities performed in rotating 3-shifts, around the clock, as well as many of the persons performing work tasks on the plant being external contractors. The working conditions are characterised by stress due to heat, radiation and physically demanding or monotonous

  9. Improvement of railway ballast maintenance approach, incorporating ballast geometry and fouling conditions

    Science.gov (United States)

    Sadeghi, J.; Motieyan-Najar, M. E.; Zakeri, J. A.; Yousefi, B.; Mollazadeh, M.

    2018-04-01

    Ballast plays an important role in the stability of railway track systems. The effectiveness of the ballast in maintaining the track stability is very much dependent on its mechanical conditions. The available ballast maintenance approaches are mainly based on only track geometry conditions (such as track profile) which do not sufficiently reflect the ballast mechanical behaviors. That is, the ballast potential of degradation (i.e., ballast long term behaviors) has been omitted. This makes the effectiveness of the current ballast maintenance approach questionable, indicating a need for a more comprehensive and effective ballast conditions assessment technique. In response to this need, two ballast condition indices based on ballast geometry degradation (BGI) and the level of ballast fouling (BFI) as the main indicators of ballast mechanical behavior were developed. The BGI is a function of the standard deviations of track alignment, unevenness and twist. The BFI was developed based on the data obtained from the ground penetration radar (GPR). Making use of the new indices, a more reliable maintenance algorithm was developed. Through illustrations of the applicability of the new maintenance algorithm in a railway line, it was shown that the new algorithm causes a considerable improvement in the maintenance effectiveness and an increase in the life cycle of railway tracks by making more effective allocation of resources and more accurate maintenance planning.

  10. Research on gesture recognition of augmented reality maintenance guiding system based on improved SVM

    Science.gov (United States)

    Zhao, Shouwei; Zhang, Yong; Zhou, Bin; Ma, Dongxi

    2014-09-01

    Interaction is one of the key techniques of augmented reality (AR) maintenance guiding system. Because of the complexity of the maintenance guiding system's image background and the high dimensionality of gesture characteristics, the whole process of gesture recognition can be divided into three stages which are gesture segmentation, gesture characteristic feature modeling and trick recognition. In segmentation stage, for solving the misrecognition of skin-like region, a segmentation algorithm combing background mode and skin color to preclude some skin-like regions is adopted. In gesture characteristic feature modeling of image attributes stage, plenty of characteristic features are analyzed and acquired, such as structure characteristics, Hu invariant moments features and Fourier descriptor. In trick recognition stage, a classifier based on Support Vector Machine (SVM) is introduced into the augmented reality maintenance guiding process. SVM is a novel learning method based on statistical learning theory, processing academic foundation and excellent learning ability, having a lot of issues in machine learning area and special advantages in dealing with small samples, non-linear pattern recognition at high dimension. The gesture recognition of augmented reality maintenance guiding system is realized by SVM after the granulation of all the characteristic features. The experimental results of the simulation of number gesture recognition and its application in augmented reality maintenance guiding system show that the real-time performance and robustness of gesture recognition of AR maintenance guiding system can be greatly enhanced by improved SVM.

  11. Improving maintenance of lost weight following a commercial liquid meal replacement program: a preliminary study.

    Science.gov (United States)

    Ames, Gretchen E; Patel, Roshni H; McMullen, Jillian S; Thomas, Colleen S; Crook, Julia E; Lynch, Scott A; Lutes, Lesley D

    2014-01-01

    Clinic-based liquid meal replacement (800kcals/day) programs produce substantial weight loss. Nevertheless, long-term maintenance remains a challenge. A limitation of maintenance programs is that they continue to promote large behavior changes that are initially required to induce weight loss which may be unsustainable long-term. The study aims were to conduct a preliminary assessment of the feasibility, acceptability, and effectiveness of a small changes maintenance intervention (SCM) for 30 patients who completed liquid meal replacement program (LMR). The 20-session SCM delivered over 52 weeks offered no preset goals for maintenance behaviors and all changes in behavior were self-selected. Participants had a median BMI of 40.9 kg/m(2) and weight of 111 kg at the start of LMR. At LMR completion, they lost 18% (21 kg) of body weight. The SCM was completed by 22 patients (73%); 19 completers (86%) attended ≥ 17 of 20 sessions with a median satisfaction rating of 9 (on a scale of 1 to 9). Completers were asked to record self-selected maintenance behaviors daily (median 351 days recorded). The most commonly reported daily behaviors were self-weighing, use of meal replacements and step counting. Median percent regain at week 52 was 14% (2.8 kg) of lost weight (range, -42 to 74%), significantly less than a median of 56% (11 kg) percent regain of lost weight (range, -78 to 110%) in a demographically similar historical control group with no maintenance intervention after LMR completion (P<0.001). Thus, SCM holds promise for improving weight maintenance. Future research should compare SCM to standard maintenance programs that promote large program-directed changes. © 2013.

  12. The mapping and preparation of human resources for NPP’S operation and maintenance in Indonesia

    International Nuclear Information System (INIS)

    Moch-Djoko Birmano; Yohanes Dwi Anggoro

    2013-01-01

    The preparation of the competent human resources (HRs) is one of the basic infrastructure of NPP’s development. IAEA recommends that at the initial activity in preparation of human resources for NPP is doing Business Process Mapping by identifying the knowledge, skills and abilities of required human resources to carry out the operation and maintenance of NPPs. This study aims to mapping and preparing of human resources for NPP’s operation and maintenance in Indonesia. The method used are mapping business processes at operation and maintenance stage of NPP, identifying positions, conducting surveys with questionnaires and calculations, and data analysis. Surveys and questionnaires to determine the level of technical competence of personnel in BATAN at operation and maintenance stage. Analysis using the Method of Gap Analysis with human resources Competency Standards Criteria based on technical competence qualifications. This study uses the assumption that the nuclear power plant will be built 2 units (twin) and start operation in 2027. The results showed that from the aspect of education, BATAN able to meet the needs of human resources at 53.64 to 73.75%. While from the aspect of training and specific work experience, participation level of BATAN’s human resources is still very low of IAEA requirements. This case caused because young human resources in BATAN who have educational qualifications, experience, training and technical certifications in the field of operation and maintenance of nuclear power plants is still limited. Based on this, there should be preparation of NPP’s human resources with establish NPP’s human resources development program based on required qualifications. (author)

  13. The improvement of maintenance service for traction networks equipment on the base of process approach

    Directory of Open Access Journals (Sweden)

    D. V. Mironov

    2014-12-01

    Full Text Available Purpose. The new methods development for improving the maintenance service for equipment of traction networks in order to increase its efficiency and quality. Methodology. In world practice of solving problems related to the quality of products and services is usually achieved by introducing quality management system in to the enterprises. The provisions of quality management system were used for solving the problem. The technologies of process engineering were used for describing the main stages of maintenance service. Findings. The development of high-speed movement and growth of its intensity, the use of electric rolling stock of a new generation require the introduction of new methods diagnostics of equipment technical state and improvement of the existing maintenance system and repair of power supply. Developing a model of business-processes, their optimization with using techniques of process engineering and system management is needed for the transition to the management system based on the process approach. From the standpoint of the process approach and in accordance with the requirements of the quality management system (ISO 9001-2009, the operation of the E (Department of electrification and power supply infrastructure sector is represented as a scheme of business-processes in which the guaranteed supply with electricity of railway and third-party consumers is defined as the main business-process of management. Each of the sub-process of power supply for consumers is described in details. The use methods and main stages of process approach for sample management system reorganization were investigated. The methodology and the application method of PDCA (Plan-Do-Check-Act closed loop to the equipment maintenance system were described. The monitoring process of traction networks maintenance using the process approach was divided into components after investigations. The technical documentation of maintenance service was investigated in

  14. Teacher Evaluation: Organizational Maintenance Versus Stimulation of Improved Teaching Performance. The New Mexico Principalship Study.

    Science.gov (United States)

    Wood, Carolyn J.; Pohland, Paul A.

    Teacher evaluation procedures appear to focus on organizational maintenance aspects more heavily than on helping teachers improve their teaching performance. This conclusion was reached after a content analysis of teacher evaluation instruments used in New Mexico schools. Items focusing on the instructional role constituted only 28% of the items…

  15. Improvement of maintenance engineering using plant network and personal digital assistant

    International Nuclear Information System (INIS)

    Otani, Yohei; Hasegawa, Takeshi; Hoshino, Masateru; Kato, Takahisa; Yokoi, Miki

    2015-01-01

    Toshiba has developed and adopted wired and/or wireless maintenance network at nuclear power plant in cooperate with industry. Toshiba also developed a tablet PC based field testing tool that enables to display test procedures and record test results in the field to improve the efficiency of such testing. Recently, we have adopted remote desktop protocol that enables to support the operator. (author)

  16. Improvement in renal function after everolimus introduction and calcineurin inhibitor reduction in maintenance thoracic transplant recipients

    DEFF Research Database (Denmark)

    Arora, Satish; Gude, Einar; Sigurdardottir, Vilborg

    2012-01-01

    The NOCTET (NOrdic Certican Trial in HEart and lung Transplantation) trial demonstrated that everolimus improves renal function in maintenance thoracic transplant (TTx) recipients. Nevertheless, introduction of everolimus is not recommended for patients with advanced renal failure. We evaluated...... NOCTET data to assess everolimus introduction amongst TTx recipients with advanced renal failure....

  17. Information management in supply chain partnering : improving maintenance processes in Dutch housing associations

    NARCIS (Netherlands)

    Debby Goedknegt

    2017-01-01

    From the article: "Abstract Maintenance processes of Dutch housing associations are often still organized in a traditional manner. Contracts are based on lowest price instead of ‘best quality for lowest price’ considering users’ demands. Dutch housing associations acknowledge the need to improve

  18. Impact of improved operation and maintenance on cohesive sediment transport in Gezira Scheme, Sudan

    NARCIS (Netherlands)

    Osman, I.S.E.

    2015-01-01

    Summary

    Efficient operation and maintenance of irrigation schemes are needed for improving the hydraulic performance of the canals, enhancing the crop yields and insuring sustainable production. There is a great need to enhance the researches and for a variety of tools such as

  19. Homologous mechanisms of visuospatial working memory maintenance in macaque and human: Properties and sources

    Science.gov (United States)

    Reinhart, Robert M.G.; Heitz, Richard P.; Purcell, Braden A.; Weigand, Pauline K.; Schall, Jeffrey D.; Woodman, Geoffrey F.

    2012-01-01

    Although areas of frontal cortex are thought to be critical for maintaining information in visuospatial working memory, the event-related potential (ERP) index of maintenance is found over posterior cortex in humans. In the present study, we reconcile these seemingly contradictory findings. Here we show that macaque monkeys and humans exhibit the same posterior ERP signature of working memory maintenance that predicts the precision of the memory-based behavioral responses. In addition, we show that the specific pattern of rhythmic oscillations in the alpha band, recently demonstrated to underlie the human visual working memory ERP component, is also present in monkeys. Next, we concurrently recorded intracranial local field potentials from two prefrontal and another frontal cortical area to determine their contribution to the surface potential indexing maintenance. The local fields in the two prefrontal areas, but not the cortex immediately posterior, exhibited amplitude modulations, timing, and relationships to behavior indicating that they contribute to the generation of the surface ERP component measured from the distal posterior electrodes. Rhythmic neural activity in the theta and gamma bands during maintenance provided converging support for the engagement of the same brain regions. These findings demonstrate that nonhuman primates have homologous electrophysiological signatures of visuospatial working memory to those of humans and that a distributed neural network, including frontal areas, underlies the posterior ERP index of visuospatial working memory maintenance. PMID:22649249

  20. Basic Characteristics of Human Erroneous Actions during Test and Maintenance Activities Leading to Unplanned Reactor Trips

    International Nuclear Information System (INIS)

    Kim, Jae Whan; Park, Jin Kyun

    2010-01-01

    Test and maintenance (T and M) activities of nuclear power plants are essential for sustaining the safety of a power plant and maintaining the reliability of plant systems and components. However, the potential of human errors during T and M activities has also the potential to induce unplanned reactor trips or power derate or making safety-related systems unavailable. According to the major incident/accident reports of nuclear power plants in Korea, contribution of human errors takes up about 20% of the total events. The previous study presents that most of human-related unplanned reactor trip events during normal power operation are associated with T and M activities (63%), which are comprised of plant maintenance activities such as a 'periodic preventive maintenance (PPM)', a 'planned maintenance (PM)' and a 'corrective maintenance (CM)'. This means that T and M activities should be a major subject for reducing the frequency of human-related unplanned reactor trips. This paper aims to introduce basic characteristics of human erroneous actions involved in the test and maintenance-induced unplanned reactor trip events that have occurred between 1986 and 2006 in Korean nuclear power plants. The basic characteristics are described by dividing human erroneous actions into planning-based errors and execution-based errors. For the events associated with planning failures, they are, firstly, classified according to existence of the work procedure and then described for what aspects of the procedure or work plan have deficiency or problem. On the other hand, for the events associated with execution failures, they are described from the aspect of external error modes

  1. Skeletal muscle structural lipids improve during weight-maintenance after a very low calorie dietary intervention

    DEFF Research Database (Denmark)

    Haugaard, Steen B; Vaag, Allan; Mu, Huiling

    2009-01-01

    -guided 24-weeks weight-maintenance program (-1.2 +/- 1.5 kg, P = ns). SMPL FA composition was determined by gas liquid chromatography. During the preceding VLCD, insulin sensitivity (HOMA-IR) and glycemic control (HbA1c) improved but no change in SMPL omega-3 FA was observed. During the weight......-maintenance program five subjects received the pancreas lipase inhibitor Orlistat 120 mg t.i.d. versus placebo. RESULTS: HOMA-IR and HbA1c stabilized and SMPL total omega-3 FA, docosahexaenoic acid and ratio of n-3/n-6 polyunsaturated FA increased by 24% (P

  2. A multicriteria decision making approach applied to improving maintenance policies in healthcare organizations.

    Science.gov (United States)

    Carnero, María Carmen; Gómez, Andrés

    2016-04-23

    decision-making group. This approach is better suited to actual health care organization practice and depending on the subsystem analysed, improvements are introduced that are not included in normal maintenance policies; in this way, not only have different maintenance policies been suggested, but also alternatives that, in each case and according to viability, provide a more complete decision tool for the maintenance manager.

  3. Present Situation and Problems of Land Improvement District as an Operation and Maintenance Organization of Land Improvement Facilities

    OpenAIRE

    長堀, 金造; 赤江, 剛夫; 大田, 征六

    1994-01-01

    Land improvement districts originally started as organizations after World War II: They are in charge of construction and operation of irrigation and drainage facilities, Development of agricultural land, reclamation from sea water, reclamation by filling, Recovery from disaster, exchange and consolidation of agricultural land and so on. As the Main construction projects were completed, the purpose of land improvement districts Has shifted from facilities construction to operation and mainten...

  4. MAPPS (Maintenance Personnel Performance Simulation): a computer simulation model for human reliability analysis

    International Nuclear Information System (INIS)

    Knee, H.E.; Haas, P.M.

    1985-01-01

    A computer model has been developed, sensitivity tested, and evaluated capable of generating reliable estimates of human performance measures in the nuclear power plant (NPP) maintenance context. The model, entitled MAPPS (Maintenance Personnel Performance Simulation), is of the simulation type and is task-oriented. It addresses a number of person-machine, person-environment, and person-person variables and is capable of providing the user with a rich spectrum of important performance measures including mean time for successful task performance by a maintenance team and maintenance team probability of task success. These two measures are particularly important for input to probabilistic risk assessment (PRA) studies which were the primary impetus for the development of MAPPS. The simulation nature of the model along with its generous input parameters and output variables allows its usefulness to extend beyond its input to PRA

  5. The Maintenance Personnel Performance Simulation (MAPPS) model: A human reliability analysis tool

    International Nuclear Information System (INIS)

    Knee, H.E.

    1985-01-01

    The Maintenance Personnel Performance Simulation (MAPPS) model is a computerized, stochastic, task-oriented human behavioral model developed to provide estimates of nuclear power plant (NPP) maintenance team performance measures. It is capable of addressing person-machine, person-environment, and person-person relationships, and accounts for interdependencies that exist between the subelements that make up the maintenance task of interest. The primary measures of performance estimated by MAPPS are: 1) the probability of successfully completing the task of interest and 2) the task duration time. MAPPS also estimates a host of other performance indices, including the probability of an undetected error, identification of the most- and least-likely error-prone subelements, and maintenance team stress profiles during task execution

  6. Maintenance of prolactin receptors in human breast cancer

    International Nuclear Information System (INIS)

    Ben-David, M.; Dror, Y.; Biran, S.

    1981-01-01

    Breast tissue specimens of 110 women with various stages of breast cancer were tested in vitro to determine their specific binding sites for human prolactin. In contrast to the case of steroid receptors, binding sites for prolactin were found in the vast majority of breast cancer tissue. Distribution profiles giving amount of prolactin receptor and their affinity coefficients were found to be similar in the tissues of women whose ages, hormonal status, or stage of breast cancer varied. These findings show that in contrast to steroid receptors, human breast cancer tissue maintains binding sites for prolactin. The findings also indicate that there may be a higher dependency of breast cancer on prolactin than on steroids. Clinical trials must be carried out to determine the role of ''positive'' prolactin receptors in prognosis and prediction of response to future hormone therapy. (author)

  7. Management of remanent lifetime. Short-term benefits of the maintenance evaluation and improvement programme

    International Nuclear Information System (INIS)

    Sainero Garcia, J.

    1993-01-01

    Remanent Lifetime Management, which is scientifically based on knowing the degradatory phenomena associated with aging, today allows us to optimize plant life through a long-term maintenance strategy combining preventive maintenance and condition monitoring programmes. Within a project for Remanent Lifetime Management (RLM), the determination of methods of control and mitigation of degradations due to aging depends on the programme of Maintenance Evaluation and Improvement (MEI). This programme, underpinned by the analysis of degradatory phenomena to which plant components are subjected, evaluates current maintenance practices and defines the complementary actions which would facilitate establishment of a long-term strategy to control aging. Together with this main objective of the RLM project, the MEI programme achieves short-term benefits since, right from the beginning, it offers solutions to mitigate and guard against degradations in crucial plant components, and generally sets out a programme to control aging. The MEI programme further serves as a tool to reach the final objectives of the new 10CFR50.65 rule, 'Requirements for Maintenance Programs for NPPs'. The MEI always offers the option should the Utility Owner decide to extend plant life. (author)

  8. Evidence Accumulation and Choice Maintenance Are Dissociated in Human Perceptual Decision Making.

    Directory of Open Access Journals (Sweden)

    Mads Lund Pedersen

    Full Text Available Perceptual decision making in monkeys relies on decision neurons, which accumulate evidence and maintain choices until a response is given. In humans, several brain regions have been proposed to accumulate evidence, but it is unknown if these regions also maintain choices. To test if accumulator regions in humans also maintain decisions we compared delayed and self-paced responses during a face/house discrimination decision making task. Computational modeling and fMRI results revealed dissociated processes of evidence accumulation and decision maintenance, with potential accumulator activations found in the dorsomedial prefrontal cortex, right inferior frontal gyrus and bilateral insula. Potential maintenance activation spanned the frontal pole, temporal gyri, precuneus and the lateral occipital and frontal orbital cortices. Results of a quantitative reverse inference meta-analysis performed to differentiate the functions associated with the identified regions did not narrow down potential accumulation regions, but suggested that response-maintenance might rely on a verbalization of the response.

  9. Investigating the causes of human error-induced incidents in the maintenance operations of petrochemical industry by using HFACS

    Directory of Open Access Journals (Sweden)

    Mohammadreza Azhdari

    2017-03-01

    Full Text Available Background & Objectives: Maintenance is an important tool for the petrochemical industries to prevent of accidents and increase operational and process safety success. The purpose of this study was to identify the possible causes of incidents caused by human error in the petrochemical maintenance activities by using Human Factors Analysis and Classification System (HFACS. Methods: This study is a cross-sectional analysis that was conducted in Zagros Petrochemical Company, Asaluyeh-Iran. A checklist of human error-induced incidents was developed based on four HFACS main levels and nineteen sub-groups. Hierarchical task analysis (HTA technique was used to identify maintenance activities and tasks. The main causes of possible incidents were identified by checklist and recorded. Corrective and preventive actions were defined depending on priority.   Results: The content analysis of worksheets of 444 activities showed 37.6% of the causes at the level of unsafe actions, 27.5% at the level of unsafe supervision, 20.9% at the level of preconditions for unsafe acts and 14% of the causes at the level of organizational effects. The HFACS sub-groups showed errors (24.36% inadequate supervision (14.89% and violations (13.26% with the most frequency. Conclusion: In order to prevent and reduce the occurrence of the identified errors, reducing the rate of the detected errors is crucial. Findings of this study showed that appropriate controlling measures such as periodical training of work procedures and supervision improvement decrease the human error-induced incidents in petrochemical industry maintenance.

  10. Comparative analysis of genome maintenance genes in naked mole rat, mouse, and human

    NARCIS (Netherlands)

    S.L. Macrae (Sheila L.); Q. Zhang (Quanwei); C. Lemetre (Christophe); I. Seim (Inge); R.B. Calder (Robert B.); J.H.J. Hoeijmakers (Jan); Y. Suh (Yousin); V.N. Gladyshev (Vadim N.); A. Seluanov (Andrei); V. Gorbunova (Vera); J. Vijg (Jan); Z.D. Zhang (Zhengdong D.)

    2015-01-01

    textabstractGenome maintenance (GM) is an essential defense system against aging and cancer, as both are characterized by increased genome instability. Here, we compared the copy number variation and mutation rate of 518 GM-associated genes in the naked mole rat (NMR), mouse, and human genomes. GM

  11. Human errors in test and maintenance of nuclear power plants. Nordic project work

    International Nuclear Information System (INIS)

    Andersson, H.; Liwaang, B.

    1985-08-01

    The present report is a summary of the NKA/LIT-1 project performed for the period 1981-1985. The report summarizes work on human error influence in test and calibration activities in nuclear power plants, reviews problems regarding optimization of the test intervals, organization of test and maintenance activities, and the analysis of human error contribution to the overall risk in test and mainenace tasks. (author)

  12. Mobile robotics for CANDU reactor maintenance: case studies and near-term improvements

    International Nuclear Information System (INIS)

    Lipsett, M. G.; Rody, K.H.

    1995-01-01

    Although robotics researchers have been promising that robotics would soon be performing tasks in hazardous environments, the reality has yet to live up to the hype. The presently available crop of robots suitable for deployment in industrial situations are remotely operated, requiring skilled users. This talk describes cases where mobile robots have been used successfully in CANDU stations, discusses the difficulties in using mobile robots for reactor maintenance, and provides near-term goals for achievable improvements in performance and usefulness. (author)

  13. Criteria and model for assessing and improving information technology maturity within maintenance

    International Nuclear Information System (INIS)

    Kans, M; Ehsanifard, K; Moniri, A

    2012-01-01

    Maintenance optimization and decision-making processes have been both influenced considerably by Information Technology (IT) developments mainly by increasing data availability. The decision-making process in its turn has affected systems trustworthiness positively. Therefore, theoretically speaking it could be said that Maintenance Management Information technology (MMIT) has the potential to provide applicable solutions for many of the maintenance management problems. Nevertheless, this potential has been hardly experienced in practice because of the mismatch between the level of IT maturity in the organizations and their selected MMIT solutions. To fill this gap this paper suggests a number of criteria which are crucial in decision making for selecting a MMIT application. The criteria are formed based on previous findings utilising an extensive literature review. A model is further developed for this purpose which is also tested on a case company active in power generation in Sweden. The model proved to be helpful when taking further improvement steps for reaching high utilization of IT in maintenance.

  14. An Improved Distribution Policy with a Maintenance Aspect for an Urban Logistic Problem

    Directory of Open Access Journals (Sweden)

    Nadia Ndhaief

    2017-07-01

    Full Text Available In this paper, we present an improved distribution plan supporting an urban distribution center (UDC to solve the last mile problem of urban freight. This is motivated by the need of UDCs to satisfy daily demand in time under a high service level in allocated urban areas. Moreover, these demands could not be satisfied in individual cases because the delivery rate can be less than daily demand and/or affected by random failure or maintenance actions of vehicles. The scope of our work is to focus on a UDC, which needs to satisfy demands in a finite horizon. To that end, we consider a distribution policy on two sequential plans, a distribution plan correlated to a maintenance plan using a subcontracting strategy with several potential urban distribution centers (UDCs and performing preventive maintenance to ensure deliveries for their allocated urban area. The choice of subcontractor will depend on distance, environmental and availability criteria. In doing so, we define a mathematical model for searching the best distribution and maintenance plans using a subcontracting strategy. Moreover, we consider delay for the next periods with an expensive penalty. Finally, we present a numerical example illustrating the benefits of our approach.

  15. Interface technology based on human cognition and understanding for the operation and maintenance of advanced human cooperative plants

    International Nuclear Information System (INIS)

    Numano, Masayoshi; Niwa, Yasuyuki; Itoh, Hiroko; Miyazaki, Keiko; Fukuto, Junji; Okazaki, Tadatsugi; Matsukura, Hiroshi; Tanaka, Kunihiko; Matsuoka, Takeshi; Liu, Qiao; Mitomo, Nobuo

    2006-01-01

    'Development of Intelligent Systems Technology for Advanced Human Cooperative Plants' was implemented as 'Nuclear Energy Fundamentals Crossover Research' by 3 institutes (The Institute of Physical and Chemical Research; RIKEN, National Institute of Advanced Industrial Science and Technology; AIST and National Maritime Research Institute; NMRI). Aiming at appropriate interaction between human and agents in Digital Maintenance Field which spreads widely in time and space, NMRI developed technologies on contraction of plant information, generalization and intuition of the information through visual presentation. Intuitive presentation gave on-site information for identifying the source of abnormalities to human operators. And a human-machine cooperation infrastructure for plant maintenance was proposed and developed, where an overview display was used to show position and state information of all the agents in the plant and each agent view was used to show the corresponding agent's information in detail. A part of this technology was implemented in a demonstration program. Two agents were developed to support human operators' plant maintenance activities in this program. This demonstration showed the effectiveness of human-agent cooperation for early plant abnormality detection. (author)

  16. Study on the methodology for predicting and preventing errors to improve reliability of maintenance task in nuclear power plant

    International Nuclear Information System (INIS)

    Hanafusa, Hidemitsu; Iwaki, Toshio; Embrey, D.

    2000-01-01

    The objective of this study was to develop and effective methodology for predicting and preventing errors in nuclear power plant maintenance tasks. A method was established by which chief maintenance personnel can predict and reduce errors when reviewing the maintenance procedures and while referring to maintenance supporting systems and methods in other industries including aviation and chemical plant industries. The method involves the following seven steps: 1. Identification of maintenance tasks. 2. Specification of important tasks affecting safety. 3. Assessment of human errors occurring during important tasks. 4. Identification of Performance Degrading Factors. 5. Dividing important tasks into sub-tasks. 6. Extraction of errors using Predictive Human Error Analysis (PHEA). 7. Development of strategies for reducing errors and for recovering from errors. By way of a trial, this method was applied to the pump maintenance procedure in nuclear power plants. This method is believed to be capable of identifying the expected errors in important tasks and supporting the development of error reduction measures. By applying this method, the number of accidents resulting form human errors during maintenance can be reduced. Moreover, the maintenance support base using computers was developed. (author)

  17. Introducing artificial depth cues to improve task performance in ITER maintenance actions

    International Nuclear Information System (INIS)

    Heemskerk, C.J.M.; Eendebak, P.T.; Schropp, G.Y.R.; Hermes, H.V.; Elzendoorn, B.S.Q.; Magielsen, A.J.

    2013-01-01

    Highlights: ► Operators regard lack of 3D perception as primary factor hindering remote maintenance. ► Promising techniques to improve depth perception are depth gauges and stereo vision. ► First experiment shows artificial depth gauges need to be designed with care. ► Second experiment shows that stereo vision improves task performance significantly. -- Abstract: Maintenance operations on ITER tokamak components will be largely performed by remote handling. In previous work it was shown that representative maintenance tasks could be performed significantly faster with direct visual feedback than with camera feedback. In post-test interviews, operators indicated that they regarded the lack of 3D perception as the primary factor hindering their performance. This paper discusses various techniques to improve depth perception in teleoperation, including stereo vision, head tracking, virtual camera views and depth gauges. The most promising techniques were tested. Performance metrics included time-to-complete, path analysis and operator work-load. In a first experiment, artificial depth gauges views were tested in a 1:1 scale hardware testbed with mechanical master-slave manipulators handled by experienced operators. Robust real-time image processing was achieved with marker-based objects. The simple depth gauge and graphical overlay did not significantly improve task performance. Operators commented on their view of the task being “obstructed” by the graphical overlay, and the depth gauge was judged not very informative. In a second experiment, real time tracking was combined with VR display including stereo and head tracking. While stereo was found to improve the task performance significantly over the 1 camera (mono) condition, head tracking unexpectedly did not

  18. Introducing artificial depth cues to improve task performance in ITER maintenance actions

    Energy Technology Data Exchange (ETDEWEB)

    Heemskerk, C.J.M., E-mail: c.heemskerk@heemskerk-innovative.nl [Heemskerk Innovative Technology, Sassenheim (Netherlands); Eendebak, P.T. [TNO Netherlands Organisation for Applied Scientific Research (Netherlands); Schropp, G.Y.R. [Heemskerk Innovative Technology, Sassenheim (Netherlands); Hermes, H.V. [TU Eindhoven (Netherlands); Elzendoorn, B.S.Q. [FOM Institute DIFFER (Dutch Institute for Fundamental Energy Research), Association EURATOM-FOM, Partner in the Trilateral Euregio Cluster, P.O. Box 1207, 3430 BE Nieuwegein (Netherlands); Magielsen, A.J. [NRG, P.O. Box 25, 1755 ZG Petten (Netherlands)

    2013-10-15

    Highlights: ► Operators regard lack of 3D perception as primary factor hindering remote maintenance. ► Promising techniques to improve depth perception are depth gauges and stereo vision. ► First experiment shows artificial depth gauges need to be designed with care. ► Second experiment shows that stereo vision improves task performance significantly. -- Abstract: Maintenance operations on ITER tokamak components will be largely performed by remote handling. In previous work it was shown that representative maintenance tasks could be performed significantly faster with direct visual feedback than with camera feedback. In post-test interviews, operators indicated that they regarded the lack of 3D perception as the primary factor hindering their performance. This paper discusses various techniques to improve depth perception in teleoperation, including stereo vision, head tracking, virtual camera views and depth gauges. The most promising techniques were tested. Performance metrics included time-to-complete, path analysis and operator work-load. In a first experiment, artificial depth gauges views were tested in a 1:1 scale hardware testbed with mechanical master-slave manipulators handled by experienced operators. Robust real-time image processing was achieved with marker-based objects. The simple depth gauge and graphical overlay did not significantly improve task performance. Operators commented on their view of the task being “obstructed” by the graphical overlay, and the depth gauge was judged not very informative. In a second experiment, real time tracking was combined with VR display including stereo and head tracking. While stereo was found to improve the task performance significantly over the 1 camera (mono) condition, head tracking unexpectedly did not.

  19. Human area MT+ shows load-dependent activation during working memory maintenance with continuously morphing stimulation.

    Science.gov (United States)

    Galashan, Daniela; Fehr, Thorsten; Kreiter, Andreas K; Herrmann, Manfred

    2014-07-11

    Initially, human area MT+ was considered a visual area solely processing motion information but further research has shown that it is also involved in various different cognitive operations, such as working memory tasks requiring motion-related information to be maintained or cognitive tasks with implied or expected motion.In the present fMRI study in humans, we focused on MT+ modulation during working memory maintenance using a dynamic shape-tracking working memory task with no motion-related working memory content. Working memory load was systematically varied using complex and simple stimulus material and parametrically increasing retention periods. Activation patterns for the difference between retention of complex and simple memorized stimuli were examined in order to preclude that the reported effects are caused by differences in retrieval. Conjunction analysis over all delay durations for the maintenance of complex versus simple stimuli demonstrated a wide-spread activation pattern. Percent signal change (PSC) in area MT+ revealed a pattern with higher values for the maintenance of complex shapes compared to the retention of a simple circle and with higher values for increasing delay durations. The present data extend previous knowledge by demonstrating that visual area MT+ presents a brain activity pattern usually found in brain regions that are actively involved in working memory maintenance.

  20. Human factors in maintenance: Development and research in Swedish nuclear power plants

    International Nuclear Information System (INIS)

    Salo, I.; Svensson, Ola

    2001-11-01

    The present report investigated previously completed, ongoing, and planned research and development projects focusing human factors and maintenance work carried out at Swedish nuclear power plants and SKI. In addition, needs for future research and development works were also investigated. Participants from all nuclear power plants and SKI were included in the study. Participants responded to a set of questions in an interview. The interviews also generated a list of future research and development projects

  1. Human factors in maintenance: development and research in Swedish nuclear power plants

    International Nuclear Information System (INIS)

    Salo, I.; Svenson, O.

    2001-11-01

    The report investigated previously completed, ongoing, and planned research and development projects focusing human factors and maintenance work carried out at Swedish nuclear power plants and SKI. In addition, needs for future research and development works were also investigated. Participants from all nuclear power plants and SKI were included in the study. Participants responded to a set of questions in an interview. The interviews also generated a list of future research and development projects. (au)

  2. Human factors in maintenance: Development and research in Swedish nuclear power plants

    Energy Technology Data Exchange (ETDEWEB)

    Salo, I. [Lund Univ. (Sweden). Dept. of Psychology; Svensson, Ola [Stockholm Univ. (Sweden). Dept. of Psychology

    2001-11-01

    The present report investigated previously completed, ongoing, and planned research and development projects focusing human factors and maintenance work carried out at Swedish nuclear power plants and SKI. In addition, needs for future research and development works were also investigated. Participants from all nuclear power plants and SKI were included in the study. Participants responded to a set of questions in an interview. The interviews also generated a list of future research and development projects.

  3. How and when will self-assessment improve maintenance of CANDU plants - evaluator's view

    International Nuclear Information System (INIS)

    Mika, K.

    1997-01-01

    Learning organizations use self-evaluation programs to compare their actual performance with their management's expectations and industry standards. In general, self-evaluations identify areas needing improvement. Self-evaluation activities in maintenance departments include self-assessments, management monitoring observations, root cause analyses, event investigations, benchmarking, use of operating experience, self-checking, and problem reporting systems. In Ontario Hydro Nuclear (OHN) we have used almost all forms of self-evaluation with mixed success. However, we did not use self-assessments. With emphasis on excellent maintenance this powerful form of self-evaluation is being introduced to all our plants. Because of its recency and relative inexperience with it, this paper is focused on self-assessment. The paper provides the author's perspective on how a self-assessment program would be evaluated by an independent internal evaluation and what attributes should be in place in order for maintenance departments to succeed in the implementation and successful continuation of the program. (author)

  4. Non destructive examinations and degradations: the use of feedback experience to improve maintenance policy

    International Nuclear Information System (INIS)

    Champigny, F.

    2007-01-01

    In France, since 1995, 58 pressurized water reactors have been operating to produce electricity. These reactors were built from 1975 to the beginning of nineties and are ranked in 4 standardized series, 900 MWe CP0 types, 900 MWe CPY types, 1300 MWe types and 1400 MWe types. The plants have undergone evolutions taking into account the feedback experience for manufacturing and construction, net power growth but also maintenance operations. In 1977 the first maintenance programs were based upon the American experience using ASME section XI code. As and when required, they have been modified with the events appeared during the operation. First of them concerned the steam generator tubes with the discover of the first primary water stress corrosion cracking at the end of the seventies then the under-clad cracking phenomenon in the 900 MWe pressure vessel nozzles. At the beginning of years 2000, the new departmental order dedicated to operation required to check and modify, if necessary, the maintenance policy to better take into account the possible damages, fast fracture studies for primary and secondary systems and, last but not least, qualification processes for non destructive examinations. These new requirements have induced a rewriting of the maintenance policies and inspection programs in the way to be more consistent with the need of an improved availability of the plants while keeping a high safety level. Through few examples, we show how the approaches and the practices have been modified in terms of non-destructive examination (NDE) and particularly the impact of the NDE qualification results. In addition, examples of the important choices between in-service inspection and repair policy are also described. (author)

  5. Improving motor reliability in nuclear power plants: Volume 1, Performance evaluation and maintenance practices

    International Nuclear Information System (INIS)

    Subudhi, M.; Gunther, W.E.; Taylor, J.H.; Sugarman, A.C.; Sheets, M.W.

    1987-11-01

    This report constitutes the first of the three volumes under this NUREG. The report presents recommendations for developing a cost-effective program for performance evaluation and maintenance of electric motors in nuclear power plants. These recommendations are based on current industry practices, available techniques for monitoring degradation in motor components, manufacturer's recommendations, operating experience, and results from two laboratory tests on aged motors. Two laboratory test reports on a small and a large motor are presented in separate volumes of this NUREG. These provide the basis for the various functional indicators recommended for maintenance programs in this report. The overall preventive maintenance program is separated into two broad areas of activity aimed at mitigating the potential effects of equipment aging: Performance Evaluation and Equipment Maintenance. The latter involves actually maintaining the condition of the equipment while the former involves those activities undertaken to monitor degradation due to aging. These monitoring methods are further categorized into periodic testing, surveillance testing, continuous monitoring and inspections. This study focuses on the methods and procedures for performing the above activities to maintain the motors operationally ready in a nuclear facility. This includes an assessment of various functional indicators to determine their suitability for trending to monitor motor component condition. The intrusiveness of test methods and the present state-of-the-art for using the test equipment in a plant environment are discussed. In conclusion, implementation of the information provided in this report, will improve motor reliability in nuclear power plants. The study indicates the kinds of tests to conduct, how and when to conduct them, and to which motors the tests should be applied. 44 refs., 12 figs., 13 tabs

  6. Maintenance Personnel Performance Simulation (MAPPS) model: a human reliability analysis tool

    International Nuclear Information System (INIS)

    Knee, H.E.

    1985-01-01

    The Maintenance Personnel Performance Simulation (MAPPS) model is a computerized, stochastic, task-oriented human behavioral model developed to provide estimates of nuclear power plant (NPP) maintenance team performance measures. It is capable of addressing person-machine, person-environment, and person-person relationships, and accounts for interdependencies that exist between the subelements that make up the maintenance task of interest. The primary measures of performance estimated by MAPPS are: (1) the probability of successfully completing the task of interest; and (2) the task duration time. MAPPS also estimates a host of other performance indices, including the probability of an undetected error, identification of the most- and least-likely error-prone subelements, and maintenance team stress profiles during task execution. The MAPPS model was subjected to a number of evaluation efforts that focused upon its practicality, acceptability, usefulness, and validity. Methods used for these efforts included a case method approach, consensus estimation, and comparison with observed task performance measures at a NPP. Favorable results, such as close agreement between task duration times for two tasks observed in the field (67.0 and 119.8 minutes, respectively), and estimates by MAPPS (72.0 and 124.0 minutes, respectively) enhance the confidence in the future use of MAPPS. 8 refs., 1 fig

  7. Managing railcar maintenance : a primer on practices and improvement opportunities for the U.S. transit industry.

    Science.gov (United States)

    2013-09-01

    This report surveys the state-of-practice of transit railcar maintenance management and fleet management practices. It emphasizes a lifecycle management approach to fleet management. It also emphasizes the role of performance improvement programs and...

  8. New roles of the human Suv3 helicase in genome maintenance

    DEFF Research Database (Denmark)

    Venø, Susanne Trillingsgaard

    During her PhD studies, Susanne Trillingsgaard Venø carried out research into the role of the human Suv3 protein in stabilising the human genome – DNA. Suv3 is a helicase that separates the two strands of the DNA’s double helix. Throughout our lives, the DNA in our cells is constantly exposed...... maintenance. Based on these new research results, the Suv3 protein could be a valuable model for genome stability as an important factor in our understanding of why we get old....

  9. American Board of Radiology Maintenance of Certification-Part IV: Practice Quality Improvement for Radiation Oncology

    International Nuclear Information System (INIS)

    Kun, Larry E.; Haffty, Bruce G.; Bosma, Jennifer; Strife, Janet L.; Hattery, Robert R.

    2007-01-01

    Maintenance of Certification is a physician-based response to public concerns about the quality of medical care and physician competency in a rapidly evolving, technically demanding specialty. American Board of Radiology (ABR) has previously described the first three components of the Maintenance of Certification. The ABR is currently developing a program in practice performance, completing Part IV of the competencies. The Practice Quality Improvement (PQI) program is meant to critically evaluate meaningful aspects of a physician's practice in a simple manner, using identifiable metrics and self-assessment to include an action plan for quality improvement. Each diplomate will be expected to complete three PQI projects during a full 10-year Maintenance of Certification cycle. Current diplomates with time-limited certificates will find prorated requirements determined by their year of certification on the ABR Website. Diplomates will have the option of completing zero to two Type I PQI projects (assessing factors relevant to clinical practice by peer review and self-reporting) and one to three Type II projects (i.e., at least one Type II projects of the three required, assessing parameters of practice by comparison with evidence-based guidelines, consensus statements, or peer comparisons; Type II projects are initiated and managed by professional societies). Several examples of Type I projects that might be offered by societies or directly through the ABR are provided, as well as highlights of the two Type II projects that have sought ABR qualification: American Society for Therapeutic Radiology and Oncology's Performance Assessment for the Advancement of Radiation Oncology Treatment program and American College of Radiology's RO-PEER program. An additional objective of the PQI is to develop national databases for future reference using aggregate data from the PQI projects

  10. Improvement of condition-based maintenance technology by utilization of thermography

    International Nuclear Information System (INIS)

    Shimada, Hiroki

    2004-01-01

    In the United States, condition-based maintenance technology comprising IR thermography (hereafter ''thermography'' for short) has been regarded in recent years as the established means for effectively improvement the performance of accident-preventive measures for nuclear power stations. As very few nuclear power plants in Japan have been utilizing the technology, measures for allowing power station personnel to use the technology with ease have been studied on an empirical basis. First, in view of improving the measuring efficiency to determine temperatures more accurately with a single measurement, principal factors affecting the measured temperature values have been analyzed. As a result, it has been found effective for accurate temperature measurement to make use of the table to radiation rates that have been determined for each facility coating specification by using a black body tape and to determine the measuring spot by avoiding rear heat sources (influence of reflection ratio) and background noise (influence of scattered light). Concurrently, as a result of determining the IR attenuation in the atmosphere, thermographic measurement has been found feasible without any significant attenuation as long as the distance is below 10 meters. Further, every power station facility (mainly electrical facilities) that is immune to thermography has been identified. These study results have been documented in the form of the ''Thermography Measurement Manual'' by also including in it the descriptions on abnormal thermal images and the judgment criteria at elevated temperatures that have been used in the United States. Based on these accomplishments, condition-based maintenance technology employing thermography has been applied to on-site investigation of nuclear power stations, and the effectiveness of thermography-aided accident-prevention has been demonstrated by detecting locally temperature rising spots of power cable joints. Moreover, with respect to maintenance

  11. The human CTC1/STN1/TEN1 complex regulates telomere maintenance in ALT cancer cells

    Energy Technology Data Exchange (ETDEWEB)

    Huang, Chenhui; Jia, Pingping; Chastain, Megan; Shiva, Olga; Chai, Weihang, E-mail: wchai@wsu.edu

    2017-06-15

    Maintaining functional telomeres is important for long-term proliferation of cells. About 15% of cancer cells are telomerase-negative and activate the alternative-lengthening of telomeres (ALT) pathway to maintain their telomeres. Recent studies have shown that the human CTC1/STN1/TEN1 complex (CST) plays a multi-faceted role in telomere maintenance in telomerase-expressing cancer cells. However, the role of CST in telomere maintenance in ALT cells is unclear. Here, we report that human CST forms a functional complex localizing in the ALT-associated PML bodies (APBs) in ALT cells throughout the cell cycle. Suppression of CST induces telomere instabilities including telomere fragility and elevates telomeric DNA recombination, leading to telomere dysfunction. In addition, CST deficiency significantly diminishes the abundance of extrachromosomal circular telomere DNA known as C-circles and t-circles. Suppression of CST also results in multinucleation in ALT cells and impairs cell proliferation. Our findings imply that the CST complex plays an important role in regulating telomere maintenance in ALT cells. - Highlights: • CST localizes at telomeres and ALT-associated PML bodies in ALT cells throughout the cell cycle. • CST is important for promoting telomeric DNA replication in ALT cells. • CST deficiency decreases ECTR formation and increases T-SCE. • CST deficiency impairs ALT cell proliferation and results in multinucleation.

  12. Implementation of Total Productive Maintenance (TPM to Improve Sheeter Machine Performance

    Directory of Open Access Journals (Sweden)

    Candra Nofri Eka

    2017-01-01

    Full Text Available This paper purpose is an evaluation of TPM implementation, as a case study at sheeter machine cut size line 5 finishing department, PT RAPP, Indonesia. Research methodology collected the Overall Equipment Effectiveness (OEE data of sheeter machine and computed its scores. Then, OEE analysis big losses, statistical analysis using SPSS 20 and focused maintenance evaluation of TPM were performed. The data collected to machine sheeter’s production for 10 months (January-October 2016. The data analyses was resulted the OEE average score of 82.75%. This score was still below the world class OEE (85% and the company target (90%. Based the big losses of OEE analysis was obtained the reduce speed losses, which most significant losses of OEE scores. The reduce speed losses value was 44.79% of total losses during the research period. The high score of these losses due to decreasing of machine production speed by operators, which intended to improve the quality of resulting products. The OEE scores statistical analysis was found breakdown losses and reduces speed losses, which significantly affected to OEE scores. Implementations of focused maintenance of TPM in the case study may need to improve because there were still occurred un-expecting losses during the research period.

  13. Improving CANDU plant operation and maintenance through retrofit information technology systems

    International Nuclear Information System (INIS)

    Lupton, L.R.; Judd, R.A.; MacBeth, M.J.

    1998-01-01

    CANDU plant owners are facing an increasingly competitive environment for the generation of electricity. To meet this challenge, all owners have identified that information technology offers opportunities for significant improvements in CANDU operation, maintenance and administration (OM and A) costs. Targeted information technology application areas include instrumentation and control, engineering, construction, operations and plant information management. These opportunities also pose challenges and issues that must be addressed if the full benefits of the advances in information technology are to be achieved. Key among these are system hardware and software maintenance, and obsolescence protection; AECL has been supporting CANDU stations with the initial development and evaluation of systems to improve plant performance and cost. Key initiatives that have been implemented or are in the process of being implemented in some CANDU plants to achieve operational benefits include: critical safety parameter monitor system; advanced computerized annunciation system; plant historical data system; and plant display system. Each system will be described in terms of its role in enhancing current CANDU plant performance and how they will contribute to future CANDU plant performance

  14. Improving CANDU plant operation and maintenance through retrofit information technology systems

    International Nuclear Information System (INIS)

    Lupton, L. R.; Judd, R. A.

    1998-01-01

    CANDU plant owners are facing an increasingly competitive environment for the generation of electricity. To meet this challenge, all owners have identified that information technology offers opportunities for significant improvements in CANDU operation, maintenance and administration (OM and A) costs. Targeted information technology application areas include instrumentation and control, engineering, construction, operations and plant information management. These opportunities also pose challenges and issues that must be addressed if the full benefits of the advances in information technology are to be achieved. Key among these are system hardware and software maintenance, and obsolescence protection. AECL has been supporting CANDU stations with the initial development and evaluation of systems to improve plant performance and cost. Five key initiatives that have been implemented or are in the process of being implemented in some CANDU plants to achieve cooperational benefits include: critical safety parameter monitor system; advanced computerized annunciation system; plant historical data system; plant display system; and digital protection system. Each system will be described in terms of its role in enhancing current CANDU plant performance and how they will contribute to future CANDU plant performance. (author). 8 refs., 3 figs

  15. Maintenance methods

    International Nuclear Information System (INIS)

    Sanchis, H.; Aucher, P.

    1990-01-01

    The maintenance method applied at the Hague is summarized. The method was developed in order to solve problems relating to: the different specialist fields, the need for homogeneity in the maintenance work, the equipment diversity, the increase of the materials used at the Hague's new facilities. The aim of the method is to create a knowhow formalism, to facilitate maintenance, to ensure the running of the operations and to improve the estimation of the maintenance cost. One of the method's difficulties is the demonstration of the profitability of the maintenance operations [fr

  16. A maintenance performance measurement framework that includesmaintenenace human factors: a case study from the electricity transmission industry

    Directory of Open Access Journals (Sweden)

    Peach, Rina

    2016-08-01

    Full Text Available Over the past two to three decades, maintenance management has undergone a paradigm shift; it is no longer seen as a necessary evil, but as an integral part of the business process that creates value for the organisation. The next step in the evolution of maintenance management is a maintenance performance measurement that includes human factors. The human factors in maintenance are well- known in the aviation industry, as it gained momentum in the early 1990s after a series of serious aviation accidents. Other industries, however, have been slow to integrate the human factor in their maintenance performance measurements. This paper discusses the results of a research project that investigated the use and importance of maintenance management performance measurements that focus specifically on human factors as part of the overall performance management system. From the research presented in this paper, ‘motivation’ and ‘competence’ were identified as the most important human performance factors in the maintenance of electricity transmission systems.

  17. Improved radioimmunoassay for human TSH

    International Nuclear Information System (INIS)

    Spencer, C.A.; Nicoloff, J.T.

    1980-01-01

    This study concerns the optimization of the human TSH (h-TSH) radioimmunoassay with special emphasis on reducing the heterogeneity of the 125 I h-TSH tracer. Enzymatic iodination of h-TSH with glucose oxidase/lactoperoxidase was shown to be superior to either low or high dose chloramine-T procedures, producing a high specific activity reagent (70-150 μCi/μg) with minimal evidence of damage. Tracer purification procedures not only affected initial immunoactivity but also storage stability and heterogeneity of the resulting 125 I h-TSH. The assay developed using these technical approaches shows a sensitivity limit of 0.005+-0.001 (S.E.M.) μU/tube; 50% displacement at 0.18+-0.08 (S.E.M.) μU/tube and complete delineation between euthyroid (n=49, 2.44+-0.18 (S.E.M.) mU/l, range 1.00-6.08) and hyperthyroid (n=62, 0.34+-0.02 (S.E.M.) mU/l, range 0.10-0.85), serum h-TSH levels. (Auth.)

  18. Human-robot collaborative navigation for autonomous maintenance management of nuclear installation

    International Nuclear Information System (INIS)

    Nugroho, Djoko Hari

    2002-01-01

    Development of human and robot collaborative navigation for autonomous maintenance management of nuclear installation has been conducted. The human-robot collaborative system is performed using a switching command between autonomous navigation and manual navigation that incorporate a human intervention. The autonomous navigation path is conducted using a novel algorithm of MLG method based on Lozano-Perez s visibility graph. The MLG optimizes the shortest distance and safe constraints. While the manual navigation is performed using manual robot tele operation tools. Experiment in the MLG autonomous navigation system is conducted for six times with 3-D starting point and destination point coordinate variation. The experiment shows a good performance of autonomous robot maneuver to avoid collision with obstacle. The switching navigation is well interpreted using open or close command to RS-232C constructed using LabVIEW

  19. Comparative analysis of genome maintenance genes in naked mole rat, mouse, and human.

    Science.gov (United States)

    MacRae, Sheila L; Zhang, Quanwei; Lemetre, Christophe; Seim, Inge; Calder, Robert B; Hoeijmakers, Jan; Suh, Yousin; Gladyshev, Vadim N; Seluanov, Andrei; Gorbunova, Vera; Vijg, Jan; Zhang, Zhengdong D

    2015-04-01

    Genome maintenance (GM) is an essential defense system against aging and cancer, as both are characterized by increased genome instability. Here, we compared the copy number variation and mutation rate of 518 GM-associated genes in the naked mole rat (NMR), mouse, and human genomes. GM genes appeared to be strongly conserved, with copy number variation in only four genes. Interestingly, we found NMR to have a higher copy number of CEBPG, a regulator of DNA repair, and TINF2, a protector of telomere integrity. NMR, as well as human, was also found to have a lower rate of germline nucleotide substitution than the mouse. Together, the data suggest that the long-lived NMR, as well as human, has more robust GM than mouse and identifies new targets for the analysis of the exceptional longevity of the NMR. © 2015 The Authors. Aging Cell published by the Anatomical Society and John Wiley & Sons Ltd.

  20. Comparative Proteomic Analysis of Supportive and Unsupportive Extracellular Matrix Substrates for Human Embryonic Stem Cell Maintenance*

    Science.gov (United States)

    Soteriou, Despina; Iskender, Banu; Byron, Adam; Humphries, Jonathan D.; Borg-Bartolo, Simon; Haddock, Marie-Claire; Baxter, Melissa A.; Knight, David; Humphries, Martin J.; Kimber, Susan J.

    2013-01-01

    Human embryonic stem cells (hESCs) are pluripotent cells that have indefinite replicative potential and the ability to differentiate into derivatives of all three germ layers. hESCs are conventionally grown on mitotically inactivated mouse embryonic fibroblasts (MEFs) or feeder cells of human origin. In addition, feeder-free culture systems can be used to support hESCs, in which the adhesive substrate plays a key role in the regulation of stem cell self-renewal or differentiation. Extracellular matrix (ECM) components define the microenvironment of the niche for many types of stem cells, but their role in the maintenance of hESCs remains poorly understood. We used a proteomic approach to characterize in detail the composition and interaction networks of ECMs that support the growth of self-renewing hESCs. Whereas many ECM components were produced by supportive and unsupportive MEF and human placental stromal fibroblast feeder cells, some proteins were only expressed in supportive ECM, suggestive of a role in the maintenance of pluripotency. We show that identified candidate molecules can support attachment and self-renewal of hESCs alone (fibrillin-1) or in combination with fibronectin (perlecan, fibulin-2), in the absence of feeder cells. Together, these data highlight the importance of specific ECM interactions in the regulation of hESC phenotype and provide a resource for future studies of hESC self-renewal. PMID:23658023

  1. The role of human error in risk analysis: Application to pre- and post-maintenance procedures of process facilities

    International Nuclear Information System (INIS)

    Noroozi, Alireza; Khakzad, Nima; Khan, Faisal; MacKinnon, Scott; Abbassi, Rouzbeh

    2013-01-01

    Human factors play an important role in the safe operation of a facility. Human factors include the systematic application of information about human characteristics and behavior to increase the safety of a process system. A significant proportion of human errors occur during the maintenance phase. However, the quantification of human error probabilities in the maintenance phase has not been given the amount of attention it deserves. This paper focuses on a human factors analysis in pre-and post- pump maintenance operations. The procedures for removing process equipment from service (pre-maintenance) and returning the equipment to service (post-maintenance) are considered for possible failure scenarios. For each scenario, human error probability is calculated for each activity using the Success Likelihood Index Method (SLIM). Consequences are also assessed in this methodology. The risk assessment is conducted for each component and the overall risk is estimated by adding individual risks. The present study is aimed at highlighting the importance of considering human error in quantitative risk analyses. The developed methodology has been applied to a case study of an offshore process facility

  2. Applying Systems Engineering to Improve the Main Gas Turbine Exhaust System Maintenance Strategy for the CG-47 Ticonderoga Class Cruiser

    Science.gov (United States)

    2015-09-01

    national security and prosperity (U.S. Navy 2014). In perspective, oceans are the lifeblood of the planet and its entire population . The National...maintenance strategy, reliability-centered maintenance, cost, schedule, performance, growth -work, new-work, optimal fleet response plan, time-directed...76 5. Main Gas Turbine Exhaust System Growth -Work ..................77 E. RECOMMENDATIONS TO IMPROVE THE MAIN GAS TURBINE EXHAUST SYSTEM

  3. Human performance improvement for nuclear power plants

    International Nuclear Information System (INIS)

    2005-01-01

    The IAEA assists NPP operating organizations to improve plant performance through a focus on human performance improvement in areas like organizational and leadership development, senior management decision making, organization and management of HPI programmes including tools needed for effective HPI implementation, safety culture enhancement, knowledge management, personnel selection and staffing, career development, training and development, work design, scheduling and conditions, procedure and other job-aid development and use, effective communications, human performance monitoring, motivation. Many NPP operating organizations in Member States, are not yet achieving the full potential of their NPP technology/equipment regarding safety, operational or economic performance due to human performance weaknesses. The IAEA's HPI (Human Performance Improvement) services provide a means for these organizations to efficiently and effectively learn from international experts and the experiences of others in improving plant performance through human performance improvements. NPP operating organizations can benefit from these services in a number of ways, including requesting a national project, participating in a regional project, or requesting an assist visit. The types of activities provided through these services include assistance in benchmarking practices of successful organizations, providing information exchange and reviews of current practices through assist missions, conducting workshops on focused human performance topics, evaluating current human performance methods, including assistance in implementing self assessment programmes and providing support to safety culture enhancement programmes based on self-assessment

  4. Expanding Educators' Contributions to Continuous Quality Improvement of American Board of Medical Specialties Maintenance of Certification.

    Science.gov (United States)

    Nora, Lois Margaret; Pouwels, Mellie Villahermosa; Irons, Mira

    2016-01-01

    The American Board of Medical Specialties board certification has transformed into a career-long process of learning, assessment, and performance improvement through its Program for Maintenance of Certification (MOC). Medical educators across many medical professional organizations, specialty societies, and other institutions have played important roles in shaping MOC and tailoring its overarching framework to the needs of different specialties. This Commentary addresses potential barriers to engagement in work related to MOC for medical school (MS) and academic health center (AHC) educators and identifies reasons for, and ways to accomplish, greater involvement in this work. The authors present ways that medical and other health professions educators in these settings can contribute to the continuous improvement of the MOC program including developing educational and assessment activities, engaging in debate about MOC, linking MOC with institutional quality improvement activities, and pursuing MOC-related scholarship. MS- and AHC-based educators have much to offer this still-young and continually improving program, and their engagement is sought, necessary, and welcomed.

  5. Continuous improvement of operation and maintenance conditions of french PWR nuclear islands

    International Nuclear Information System (INIS)

    Bitsch, D.

    1985-05-01

    Improvement of the nuclear island design, to facilitate maintenance and working conditions during plant shutdown, has been a subject of particular attention within the French PWR program. Standardization and industrial concentration created an unusually favourable context for approaching this objective. Progress efforts supported by the feedback of actual operating experience were pursued in the areas of plant layout-equipment installation, and on the design and technology of the component themselves. The progress efforts on the design and technology of the components were pursued along several paths including: - the resistance increase of specific parts submitted to various forms of in-service damage, - the reduction of the extent and duration of work during plant outages and - the reduction of the Occupational Radiation Exposure (ORE), one of the most important axes of development, through the appropriate selection of less releasing materials, the implementation of more efficient decontamination systems and by the use of robots

  6. CONSIDERATIONS UPON DESIGNING MODULAR CONSTRUCTIONS FOR IMPROVING THE PRODUCTS ASSEMBLING, MAINTENANCE AND RECYCLING PROCESSES

    Directory of Open Access Journals (Sweden)

    BÂRSAN Lucian

    2015-11-01

    Full Text Available Modular constructions are frequently used in industry because of their multiple advantages. Used from the antiquity as a measuring system that ensured good proportions for the objects or buildings, the module is used in present industry as a tool for improving the product maintenance, repair, upgrading, and/or recycling. Modular constructions can be assembled and disassembled easily, facilitating the postuse actions like subassemblies reuse, or materials recovering for the recycling process. An important aspect of this paper is that designers should create the modular solution even from the conceptual design stage and build a structure of functions based on well motivated arguments and which can easily be brake out according to technological possibilities, product functioning and assembly solutions.

  7. Opioid maintenance therapy in Switzerland: an overview of the Swiss IMPROVE study.

    Science.gov (United States)

    Besson, J; Beck, T; Wiesbeck, G; Hämmig, R; Kuntz, A; Abid, S; Stohler, R

    2014-01-01

    Switzerland's drug policy model has always been unique and progressive, but there is a need to reassess this system in a rapidly changing world. The IMPROVE study was conducted to gain understanding of the attitudes and beliefs towards opioid maintenance therapy (OMT) in Switzerland with regards to quality and access to treatment. To obtain a "real-world" view on OMT, the study approached its goals from two different angles: from the perspectives of the OMT patients and of the physicians who treat patients with maintenance therapy. The IMPROVE study collected a large body of data on OMT in Switzerland. This paper presents a small subset of the dataset, focusing on the research design and methodology, the profile of the participants and the responses to several key questions addressed by the questionnaires. IMPROVE was an observational, questionnaire-based cross-sectional study on OMT conducted in Switzerland. Respondents consisted of OMT patients and treating physicians from various regions of the country. Data were collected using questionnaires in German and French. Physicians were interviewed by phone with a computer-based questionnaire. Patients self-completed a paper-based questionnaire at the physicians' offices or OMT treatment centres. A total of 200 physicians and 207 patients participated in the study. Liquid methadone and methadone tablets or capsules were the medications most commonly prescribed by physicians (60% and 20% of patient load, respectively) whereas buprenorphine use was less frequent. Patients (88%) and physicians (83%) were generally satisfied with the OMT currently offered. The current political framework and lack of training or information were cited as determining factors that deter physicians from engaging in OMT. About 31% of OMT physicians interviewed were ≥60 years old, indicating an ageing population. Diversion and misuse were considered a significant problem in Switzerland by 45% of the physicians. The subset of IMPROVE data

  8. Evaluation of implementation an Integrated Safety and Preventive Maintenance System for Improving of Safety Indexes

    Directory of Open Access Journals (Sweden)

    I mohammadfam

    2014-03-01

    Full Text Available Accident analysis shows that one of the main reasons for accidents is non-integration of maintenance units with safety. Merging these two processes through an integrated system can reduce and or eliminate accidents, diseases, and environmental pollution. These issues lead to improvement in organizational performance, as well. The aim of this study is to design and establish an integrated system for obtaining the aforementioned goal. Integration was carried out at Nirou Moharreke Machine Tools Company via Structured System Analysis & Design Method (SSADM. In order to measure the effectiveness of the system, selected indexes were compared using statistical methods prior and after system establishment. Results show that the accident severity index reduced from 135.46 in 2010, to 43.85 in 2012. Moreover, system effectiveness improved equipment reliability and availability (e.g. reliability of the Pfeiffer Milling machine (P (t>50 increased from 0.89 in 2010, to 0.9 in 2012. This system by forecasting various failures, and planning and designing the required operations for preventing occurrence of these failures, plays an important role in improving safety conditions of equipment, and increasing organizational performance, and is capable of presenting an excellent accident prevention program.

  9. An improved segmentation-based HMM learning method for Condition-based Maintenance

    International Nuclear Information System (INIS)

    Liu, T; Lemeire, J; Cartella, F; Meganck, S

    2012-01-01

    In the domain of condition-based maintenance (CBM), persistence of machine states is a valid assumption. Based on this assumption, we present an improved Hidden Markov Model (HMM) learning algorithm for the assessment of equipment states. By a good estimation of initial parameters, more accurate learning can be achieved than by regular HMM learning methods which start with randomly chosen initial parameters. It is also better in avoiding getting trapped in local maxima. The data is segmented with a change-point analysis method which uses a combination of cumulative sum charts (CUSUM) and bootstrapping techniques. The method determines a confidence level that a state change happens. After the data is segmented, in order to label and combine the segments corresponding to the same states, a clustering technique is used based on a low-pass filter or root mean square (RMS) values of the features. The segments with their labelled hidden state are taken as 'evidence' to estimate the parameters of an HMM. Then, the estimated parameters are served as initial parameters for the traditional Baum-Welch (BW) learning algorithms, which are used to improve the parameters and train the model. Experiments on simulated and real data demonstrate that both performance and convergence speed is improved.

  10. Final Report on the Operation and Maintenance Improvement Program for Concentrating Solar Power Plants

    International Nuclear Information System (INIS)

    Cohen, Gilbert E.; Kearney, David W.; Kolb, Gregory J.

    1999-01-01

    This report describes the results of a six-year, $6.3 million project to reduce operation and maintenance (O ampersand M) costs at power plants employing concentrating solar power (CSP) technology. Sandia National Laboratories teamed with KJC Operating Company to implement the O ampersand M Improvement Program. O ampersand M technologies developed during the course of the program were demonstrated at the 150-MW Kramer Junction solar power park located in Boron, California. Improvements were made in the following areas: (a) efficiency of solar energy collection, (b) O ampersand M information management, (c) reliability of solar field flow loop hardware, (d) plant operating strategy, and (e) cost reduction associated with environmental issues. A 37% reduction in annual O ampersand M costs was achieved. Based on the lessons learned, an optimum solar- field O ampersand M plan for future CSP plants is presented. Parabolic trough solar technology is employed at Kramer Junction. However, many of the O ampersand M improvements described in the report are also applicable to CSP plants based on solar power tower or dish/engine concepts

  11. Final Report on the Operation and Maintenance Improvement Program for Concentrating Solar Power Plants

    Energy Technology Data Exchange (ETDEWEB)

    Cohen Gilbert E.; Kearney, David W.; Kolb, Gregory J.

    1999-06-01

    This report describes the results of a six-year, $6.3 million project to reduce operation and maintenance (O&M) costs at power plants employing concentrating solar power (CSP) technology. Sandia National Laboratories teamed with KJC Operating Company to implement the O&M Improvement Program. O&M technologies developed during the course of the program were demonstrated at the 150-MW Kramer Junction solar power park located in Boron, California. Improvements were made in the following areas: (a) efficiency of solar energy collection, (b) O&M information management, (c) reliability of solar field flow loop hardware, (d) plant operating strategy, and (e) cost reduction associated with environmental issues. A 37% reduction in annual O&M costs was achieved. Based on the lessons learned, an optimum solar- field O&M plan for future CSP plants is presented. Parabolic trough solar technology is employed at Kramer Junction. However, many of the O&M improvements described in the report are also applicable to CSP plants based on solar power tower or dish/engine concepts.

  12. Improvement of quality of life following 6 months of methadone maintenance therapy in Malaysia.

    Science.gov (United States)

    Baharom, Nizam; Hassan, Mohd Rohaizat; Ali, Norsiah; Shah, Shamsul Azhar

    2012-08-01

    Methadone Maintenance Therapy (MMT) is one of the popular choices for drug substitution therapy and is fairly new in Malaysia. Aside from its role in harm reduction against HIV infection, MMT programme may potentially enhances clients' quality of life. This study aims to identify the impact of MMT programme on clients' quality of life after 6 months in treatment and to explore factors that may be associated with changes in their quality of life. In this retrospective report review, 122 subjects from 2 government MMT clinics were selected from the district of Tampin, Negeri Sembilan, Malaysia. The raw score from the WHO Quality of Life questionnaire (WHOQOL-BREF), at baseline and 6 months after therapy were collected and converted to 0-100 scale form to give quality of life scores for four domains; physical, psychological, social relationships and environment. Other variables of interest were socio-demography, age when joining MMT programme, age and duration of illicit drug use, HIV and Hepatitis C status, and the Opiate Treatment Index (OTI) score on drug use, sexual and social aspect at the baseline. Statistical analysis used the SPSS version 16. There was significant improvement in all four domains of quality of life, after 6 months of MMT. The largest improvement was for psychological domain (mean score difference 15.54 ± 20.81). Multivariable linear regression analysis showed that, for the physical domain, there was no significant predictor. For both the psychological and social domains, having tertiary education is a significant predictor for improvement in both aspects of quality of life. Negative HIV status is associated with improvement for the environment domain. There was a significant short term improvement in the quality of life of MMT clients who stayed in the programme for at least 6 months in the district of Tampin, Negeri Sembilan, Malaysia.

  13. Preventative Maintenance.

    Science.gov (United States)

    Migliorino, James

    Boards of education must be convinced that spending money up front for preventive maintenance will, in the long run, save districts' tax dollars. A good program of preventive maintenance can minimize disruption of service; reduce repair costs, energy consumption, and overtime; improve labor productivity and system equipment reliability; handle…

  14. JIT maintenance improves the productivity and energy efficiency of the system

    Directory of Open Access Journals (Sweden)

    Marković Željko M.

    2016-01-01

    Full Text Available Maintenance planning in order to ensure the smooth functioning of the system, optimal interaction of system with the environment, and timely responses to the set requirements is one of the most important internal resources of the organization. Just-In-Time Maintenance enables rarely downtime and lower maintenance costs throughout the life cycle of the system, and dramatically increases the productivity and energy efficiency of the entire system. By adopting of the Just-In-Time Maintenance philosophy, minimum of objective function of energy or production system, as well as of production of services system, is achieved.

  15. Using lean methodology to improve efficiency of electronic order set maintenance in the hospital.

    Science.gov (United States)

    Idemoto, Lori; Williams, Barbara; Blackmore, Craig

    2016-01-01

    Order sets, a series of orders focused around a diagnosis, condition, or treatment, can reinforce best practice, help eliminate outdated practice, and provide clinical guidance. However, order sets require regular updates as evidence and care processes change. We undertook a quality improvement intervention applying lean methodology to create a systematic process for order set review and maintenance. Root cause analysis revealed challenges with unclear prioritization of requests, lack of coordination between teams, and lack of communication between producers and requestors of order sets. In March of 2014, we implemented a systematic, cyclical order set review process, with a set schedule, defined responsibilities for various stakeholders, formal meetings and communication between stakeholders, and transparency of the process. We first identified and deactivated 89 order sets which were infrequently used. Between March and August 2014, 142 order sets went through the new review process. Processing time for the build duration of order sets decreased from a mean of 79.6 to 43.2 days (pLean production principles to the order set review process resulted in significant improvement in processing time and increased quality of orders. As use of order sets and other forms of clinical decision support increase, regular evidence and process updates become more critical.

  16. Human mortality improvement in evolutionary context

    DEFF Research Database (Denmark)

    Burger, Oskar; Baudisch, Annette; Vaupel, James W

    2012-01-01

    Life expectancy is increasing in most countries and has exceeded 80 in several, as low-mortality nations continue to make progress in averting deaths. The health and economic implications of mortality reduction have been given substantial attention, but the observed malleability of human mortality...... about 4 of the roughly 8,000 human generations that have ever lived. Moreover, mortality improvement in humans is on par with or greater than the reductions in mortality in other species achieved by laboratory selection experiments and endocrine pathway mutations. This observed plasticity in age...

  17. Introducing artificial depth cues to improve task performance in ITER maintenance actions

    NARCIS (Netherlands)

    Heemskerk, C.J.M.; Eendebak, P.T.; Schropp, G.Y.R.; Hermes, H.V.; Elzendoorn, B.S.Q.; Magielsen, A.J.

    2013-01-01

    Maintenance operations on ITER tokamak components will be largely performed by remote handling. In previous work it was shown that representative maintenance tasks could be performed significantly faster with direct visual feedback than with camera feedback. In post-test interviews, operators

  18. Residual life management. Maintenance improvement; Gestion de vida remanente. Mejora del mantenimiento

    Energy Technology Data Exchange (ETDEWEB)

    Sainero Garcia, J; Hevia Ruperez, F

    1996-12-31

    The terms Residual Life Management, Life Cycle Management and Long-Term Management are synonymous with a concept which aims to establish efficient maintenance for the profitable and safe operation of a power plant for as long as possible. A Residual Life Management programme comprises a number of stages, of which Maintenance Evaluation focuses on how power plant maintenance practices allow the mitigation and control of component ageing. with this objective in mind, a methodology has been developed for the analysis of potential degradative phenomena acting on critical components in terms of normal power plant maintenance practices. This methodology applied to maintenance evaluation enables the setting out of a maintenance programme based on the Life Management concept, and the programme`s subsequent up-dating to allow for new techniques and methods. Initial applications have shown that although, in general terms, power plant maintenance is efficient, the way in which Residual Life Management is approached requires changes in maintenance practices. These changes range from modifications to existing inspection and surveillance methods or the establishment of new ones, to the monitoring of trends or the performance of additional studies, the purpose of which is to provide an accurate evaluation of the condition of the installations and the possibility of life extension. (Author)

  19. A Heuristic for Improving Legacy Software Quality during Maintenance: An Empirical Case Study

    Science.gov (United States)

    Sale, Michael John

    2017-01-01

    Many organizations depend on the functionality of mission-critical legacy software and the continued maintenance of this software is vital. Legacy software is defined here as software that contains no testing suite, is often foreign to the developer performing the maintenance, lacks meaningful documentation, and over time, has become difficult to…

  20. The Design of Management Practices To Improve the Physical Plant Maintenance of Southwest Texas Junior College.

    Science.gov (United States)

    Box, Wilford Winston

    A study was conducted of the physical plant maintenance department (PPMD) of Southwest Texas Junior College (SWTJC), in order to determine if the department was structured as a functional organization, if maintenance control procedures were in place, and if efficient management practices were being used. Consultations with the director of the PPMD…

  1. Human biomonitoring after chemical incidents and during short-term maintenance work as a tool for exposure analysis and assessment.

    Science.gov (United States)

    Bader, M; Van Weyenbergh, T; Verwerft, E; Van Pul, J; Lang, S; Oberlinner, C

    2014-12-15

    Human biomonitoring (HBM) is frequently used for the analysis and assessment of exposure to chemicals under routine working conditions. In recent years, HBM has also been applied to monitor the exposure of the general population, and of emergency responders in the aftermath of chemical incidents. Two examples of targeted HBM programs in the chemical industry are described and discussed in this paper: (1) analysis and assessment of the exposure of firefighters and chemical workers after the spill of p-chloroaniline from a burning chemical barrel, and (2) biomonitoring of maintenance workers potentially exposed to benzene during regular turnarounds. The results of these investigations underline that human biomonitoring contributes substantially to comprehensive exposure analyses, human health risk assessments and communication. In addition, regular HBM surveillance and feedback can assist in the continuous improvement of workplace safety measures and exposure control. In conclusion, data on accidental or short-term exposure to hazardous chemicals are an important source of information for the further development of limit and assessment values, the validation of biomarkers and of targeted HBM programs for both routine monitoring and disaster management. Copyright © 2014 Elsevier Ireland Ltd. All rights reserved.

  2. Improving maintenance medication adherence in adult inflammatory bowel disease patients: a pilot study

    Directory of Open Access Journals (Sweden)

    Michelle L. Matteson-Kome

    2014-01-01

    Full Text Available Medication nonadherence in inflammatory bowel disease (IBD may lead to suboptimal control of the disease, decreased quality of life, and poor outcomes. This pilot study evaluated the feasibility, intervention mechanism, and potential effectiveness of a three-month continuous self-improvement (CSI intervention to enhance medication adherence (MA in adult nonadherent IBD patients. Adult IBD patients taking a daily or twice-daily dosed maintenance medication were screened electronically for two months to determine baseline MA levels. Nonadherent IBD participants were randomized to the CSI or the attention control (AC intervention and monitored for three months. The CSI intervention consisted of a data evaluation and system refinement process in which system changes were identified and implemented. The AC group was given educational information regarding IBD disease process, extra-intestinal manifestations of IBD, and medical therapy. Demographic statistics, change scores for within and between- group differences, and effect size estimates were calculated. Nine nonadherent participants (medication adherence score <0.85 were eligible for randomization. The intervention was found feasible and acceptable. Although no statistically significant improvement in MA was found (P=0.14, adherence improved in 3 of 4 of the CSI group and 1 of 2 in the attention control group. The effect size calculation of 1.9 will determine the sample size for future study. The results of this pilot study showed the intervention was feasible and had a positive effect on MA change score and adherence levels. A larger fully powered study is needed to test of the effectiveness of this innovative intervention.

  3. Beneficial Effects of a Dietary Weight Loss Intervention on Human Gut Microbiome Diversity and Metabolism Are Not Sustained during Weight Maintenance.

    Science.gov (United States)

    Heinsen, Femke-Anouska; Fangmann, Daniela; Müller, Nike; Schulte, Dominik M; Rühlemann, Malte C; Türk, Kathrin; Settgast, Ute; Lieb, Wolfgang; Baines, John F; Schreiber, Stefan; Franke, Andre; Laudes, Matthias

    2016-01-01

    In the present study, we examined the effect of a very low-calorie diet(VLCD)-based obesity program on human gut microbiome diversity and metabolism during weight loss and weight maintenance. Obese subjects underwent 3 months of VLCD followed by 3 months of weight maintenance. A lean and an obese control group were included. The microbiome was characterized by performing high-throughput dual-indexed 16S rDNA amplicon sequencing. At baseline, a significant difference in the Firmicutes/Bacteroidetes ratio between the lean and obese individuals was observed (p = 0.047). The VLCD resulted in significant alterations in gut microbiome diversity from baseline to 3 months (p = 0.0053). Acinetobacter represented an indicator species for the observed effect (indicator value = 0.998, p = 0.006). Metabolic analyses revealed alterations of the bacterial riboflavin pathway from baseline to 3 months (pnom = 0.0078). These changes in diversity and bacterial metabolism induced by VLCD diminished during the weight maintenance phase, despite sustained reductions in body weight and sustained improvements of insulin sensitivity. The present data show that a VLCD is able to beneficially alter both gut microbiome diversity and metabolism in obese humans, but that these changes are not sustained during weight maintenance. This finding might suggest that the microbiome should be targeted during obesity programs. © 2016 The Author(s) Published by S. Karger GmbH, Freiburg.

  4. Beneficial Effects of a Dietary Weight Loss Intervention on Human Gut Microbiome Diversity and Metabolism Are Not Sustained during Weight Maintenance

    Directory of Open Access Journals (Sweden)

    Femke-Anouska Heinsen

    2016-11-01

    Full Text Available Objective: In the present study, we examined the effect of a very low-calorie diet(VLCD-based obesity program on human gut microbiome diversity and metabolism during weight loss and weight maintenance. Methods: Obese subjects underwent 3 months of VLCD followed by 3 months of weight maintenance. A lean and an obese control group were included. The microbiome was characterized by performing high-throughput dual-indexed 16S rDNA amplicon sequencing. Results: At baseline, a significant difference in the Firmicutes/Bacteroidetes ratio between the lean and obese individuals was observed (p = 0.047. The VLCD resulted in significant alterations in gut microbiome diversity from baseline to 3 months (p = 0.0053. Acinetobacter represented an indicator species for the observed effect (indicator value = 0.998, p = 0.006. Metabolic analyses revealed alterations of the bacterial riboflavin pathway from baseline to 3 months (pnom = 0.0078. These changes in diversity and bacterial metabolism induced by VLCD diminished during the weight maintenance phase, despite sustained reductions in body weight and sustained improvements of insulin sensitivity. Conclusion: The present data show that a VLCD is able to beneficially alter both gut microbiome diversity and metabolism in obese humans, but that these changes are not sustained during weight maintenance. This finding might suggest that the microbiome should be targeted during obesity programs.

  5. Maintenance Mentor

    National Research Council Canada - National Science Library

    Jacobs, John

    2003-01-01

    Maintenance Mentor (MXM) is a research effort conducted by a joint AFRL/HESR and Northrop Grumman Information Technology team to identify the basic, high-level requirements necessary for improving flight line diagnostic capabilities...

  6. Improving lumen maintenance by nanopore array dispersed quantum dots for on-chip light emitting diodes

    Science.gov (United States)

    Chen, Quan; Yang, Fan; Wan, Renzhuo; Fang, Dong

    2017-12-01

    The temperature stability of quantum dots (QDs), which is crucial for integrating into high power light-emitting diodes (LEDs) in the on-chip configuration, needs to be further improved. In this letter, we report warm white LEDs, where CdSe/ZnS nanoparticles were incorporated into a porous anodic alumina (PAA) matrix with a chain structure by the self-assembly method. Experiments demonstrate that the QD concentration range in toluene solvent from 1% mg/μl to 1.2% mg/μl in combination with the PAA matrix shows the best luminous property. To verify the reliability of the as-prepared device, a comparison experiment was conducted. It indicates excellent lumen maintenance of the light source and less chromaticity coordinate shift under accelerated life testing conditions. Experiments also prove that optical depreciation was only up to 4.6% of its initial value after the 1500 h aging test at the junction temperature of 76 °C.

  7. Maintenance and improvement of dairy feed quality by radiation for distribution system

    International Nuclear Information System (INIS)

    Kobayashi, Ryoei; Kawamoto, Hidenori; Uegaki, Ryuichi; Tanaka, Osamu; Ando, Sada; Akiyama, Noriaki; Yamada, Akio

    1997-01-01

    With an aim to improve the quality of crude feed and its maintenance, γ-ray radiation was carried out during the steps of preparation and storage of feed and the effects on the fermentation of silage crude feed and mixed feed were investigated. Of the γ-ray radiation significant effects on general constituents in the silage were not observed immediately after the radiation, but it was clear that the contents of fibrous components were apt to increase one month later. The ratio, VBN/TN in the silage decreased with the elevation of radiation dose. Further it was found that radiation at 16 Gy or more is needed to prevent butyric acid fermentation in the silage and aerobic deterioration. In addition, the amount of peroxide lipids was not increased by the γ-radiation, suggesting that no adverse effects on the quality of the feed in silage might be caused by radiation. Thus, it was concluded that γ-radiation in appropriate conditions has favorable influence on silage fermentation. (M.N.)

  8. Improved quality of input data for maintenance optimization using expert judgment

    International Nuclear Information System (INIS)

    Oien, Knut

    1998-01-01

    Most maintenance optimization models need an estimate of the so-called 'naked' failure rate function as input. In practice it is very difficult to estimate the 'naked' failure rate, because overhauls and other preventive maintenance actions tend to 'corrupt' the recorded lifelengths. The purpose of this paper is to stress the importance of utilizing the knowledge of maintenance engineers, i.e., expert judgment, in addition to recorded equipment lifelengths, in order to get credible input data. We have shown that without utilizing expert judgment, the estimated mean time to failure may be strongly biased, often by a factor of 2-3, depending on the life distribution that is assumed. We recommend including a simple question about the mean remaining lifelength on the work-order forms. By this approach the knowledge of maintenance engineers may be incorporated in a simple and cost-effective way

  9. Military Real Property Maintenance: Management Improvements are needed to Ensure Adequate Facilities

    National Research Council Canada - National Science Library

    Chan, Kwai-Cheung

    2000-01-01

    ... about $5 billion for each of the past 4 years (fiscal years 1996-1999). Separate accounts are used to fund maintenance and repair of family housing, many industrial-related facilities, and many military medical facilities...

  10. Education as a Basic Element of Improving Professional Important Qualities of Aviation Technical Maintenance Personnel

    Directory of Open Access Journals (Sweden)

    Gorbačovs Oļegs

    2016-12-01

    Full Text Available In this article the importance of professional qualities, competence and their increase, directly dependent on the training of aviation technical maintenance personnel and determination the level of flight safety is covered. This publication analyses necessary training and requirements for aviation technical personnel involved in aircraft maintenance, as well as the requirements for aviation training organizations, defined as per Part-147, for such personnel preparation and training.

  11. Human fetal liver stromal cells that overexpress bFGF support growth and maintenance of human embryonic stem cells.

    Directory of Open Access Journals (Sweden)

    Jiafei Xi

    Full Text Available In guiding hES cell technology toward the clinic, one key issue to be addressed is to culture and maintain hES cells much more safely and economically in large scale. In order to avoid using mouse embryonic fibroblasts (MEFs we isolated human fetal liver stromal cells (hFLSCs from 14 weeks human fetal liver as new human feeder cells. hFLSCs feeders could maintain hES cells for 15 passages (about 100 days. Basic fibroblast growth factor (bFGF is known to play an important role in promoting self-renewal of human embryonic stem (hES cells. So, we established transgenic hFLSCs that stably express bFGF by lentiviral vectors. These transgenic human feeder cells--bFGF-hFLSCs maintained the properties of H9 hES cells without supplementing with any exogenous growth factors. H9 hES cells culturing under these conditions maintained all hES cell features after prolonged culture, including the developmental potential to differentiate into representative tissues of all three embryonic germ layers, unlimited and undifferentiated proliferative ability, and maintenance of normal karyotype. Our results demonstrated that bFGF-hFLSCs feeder cells were central to establishing the signaling network among bFGF, insulin-like growth factor 2 (IGF-2, and transforming growth factor β (TGF-β, thereby providing the framework in which hES cells were instructed to self-renew or to differentiate. We also found that the conditioned medium of bFGF-hFLSCs could maintain the H9 hES cells under feeder-free conditions without supplementing with bFGF. Taken together, bFGF-hFLSCs had great potential as feeders for maintaining pluripotent hES cell lines more safely and economically.

  12. The analysis of human error as causes in the maintenance of machines: a case study in mining companies

    Directory of Open Access Journals (Sweden)

    Kovacevic, Srdja

    2016-12-01

    Full Text Available This paper describes the two-step method used to analyse the factors and aspects influencing human error during the maintenance of mining machines. The first step is the cause-effect analysis, supported by brainstorming, where five factors and 21 aspects are identified. During the second step, the group fuzzy analytic hierarchy process is used to rank the identified factors and aspects. A case study is done on mining companies in Serbia. The key aspects are ranked according to an analysis that included experts who assess risks in mining companies (a maintenance engineer, a technologist, an ergonomist, a psychologist, and an organisational scientist. Failure to follow technical maintenance instructions, poor organisation of the training process, inadequate diagnostic equipment, and a lack of understanding of the work process are identified as the most important causes of human error.

  13. Sexual dysfunction improved in heroin-dependent men after methadone maintenance treatment in Tianjin, China.

    Directory of Open Access Journals (Sweden)

    Minying Zhang

    Full Text Available OBJECTIVE: To investigate whether methadone maintenance treatment (MMT is correlated with sexual dysfunction in heroin-dependent men and to determine the prevalence and risk factors of sexual dysfunction among men on MMT. METHODS: The study included a retrospective survey and a cross-sectional survey which contained interviews of 293 men who are currently engaged in MMT. The results of the two surveys were compared. For a subset of 43 participants, radioimmunoassay was additionally conducted using retrospective and prospective blood samples to test the levels of plasma testosterone and luteinizing hormone. Other study evaluations were the International Index of Erectile Function (IIEF-15, and Self-rating Depression Scale. RESULTS: Sexual dysfunction in all five IIEF-15 domains (erectile function, orgasmic function, sexual desire, intercourse satisfaction, and overall satisfaction was strongly associated with long-term use of heroin. A decrease in the severity of sexual dysfunction was associated with MMT initiation. Erectile dysfunction, lack of sexual desire, inability to orgasm, and lack of intercourse satisfaction were significantly correlated with increasing age of the participants. Methadone dose and duration of methadone treatment were not found to be associated with sexual dysfunction. The level of plasma testosterone significantly declined during methadone treatment, but results from multivariate analysis indicated low levels of testosterone were not the main cause of sexual dysfunction. No correlation between reported depression status and sexual function was found. CONCLUSIONS: While high levels of sexual dysfunction were reported by heroin-dependent men in our study before and after MMT initiation, MMT appears to be correlated with improved sexual function in the population of the study.

  14. Improving Human Resources Recruitment in Maritime Domain

    OpenAIRE

    Surugiu Felicia; Dragomir Cristina

    2011-01-01

    In order to improve maritime human resources recruitment, most crewing and shipping companies implement an internal procedure of recruitment and management of ship’s crew. Based on observations at several crewing companies, this paper presents an example of such procedure meant to ensure that qualified and competent personnel is recruited and all ships in the fleet have crew members understanding their roles, duties and responsibilities and capable of working effectively in teams

  15. Design for improved maintenance of the fiber-optic cable system (As carried out in a concurrent engineering environment)

    Science.gov (United States)

    Tremoulet, P. C.

    The author describes a number of maintenance improvements in the Fiber Optic Cable System (FOCS). They were achieved during a production phase pilot concurrent engineering program. Listed in order of importance (saved maintenance time and material) by maintenance level, they are: (1) organizational level: improved fiber optic converter (FOC) BITE; (2) Intermediate level: reduced FOC adjustments from 20 to 2; partitioned FOC into electrical and optical parts; developed cost-effective fault isolation test points and test using standard test equipment; improved FOC chassis to have lower mean time to repair; and (3) depot level: revised test requirements documents (TRDs) for common automatic test equipment and incorporated ATE testability into circuit and assemblies and application-specific integrated circuits. These improvements met this contract's tailored logistics MIL-STD 1388-1A requirements of monitoring the design for supportability and determining the most effective support equipment. Important logistics lessons learned while accomplishing these maintainability and supportability improvements on the pilot concurrent engineering program are also discussed.

  16. Study on the improvement of working environment at night in maintenance works at nuclear power plants

    International Nuclear Information System (INIS)

    Hiramoto, Mitsuru; Kotani, Fumio

    2000-01-01

    At the maintenance work site in nuclear power plants, due to the shortening (reduction of a regular inspection period) of the regular inspection period, the tendency toward working on around-the-clock basis has increased; thus, nighttime work is on the rise. Based upon research both locally and internationally, as well as examples of measures against such a tendency and the results of on-site surveys of the environment surrounding maintenance works at nuclear power plants, the author comprehensively studied the effects of nighttime work on workers, the measures to cope with the situation, and how a working environment for nighttime work should be. Based on the results, the authors made a guidebook for nighttime maintenance work at nuclear power plants. This guidebook, which deals with the subject of nighttime maintenance work at nuclear power plants, is quite unique in the world. It is expected that by using this guidebook, the quality of nighttime maintenance work and the levels of techniques/skills would be enhanced and maintained, and the safety of workers would be ensured, promoting considerably thus the establishment of a comfortable workplace. (author)

  17. Study on the improvement of working environment at night in maintenance works at nuclear power plants

    Energy Technology Data Exchange (ETDEWEB)

    Hiramoto, Mitsuru; Kotani, Fumio [Institute of Nuclear Safety System Inc., Seika, Kyoto (Japan)

    2000-09-01

    At the maintenance work site in nuclear power plants, due to the shortening (reduction of a regular inspection period) of the regular inspection period, the tendency toward working on around-the-clock basis has increased; thus, nighttime work is on the rise. Based upon research both locally and internationally, as well as examples of measures against such a tendency and the results of on-site surveys of the environment surrounding maintenance works at nuclear power plants, the author comprehensively studied the effects of nighttime work on workers, the measures to cope with the situation, and how a working environment for nighttime work should be. Based on the results, the authors made a guidebook for nighttime maintenance work at nuclear power plants. This guidebook, which deals with the subject of nighttime maintenance work at nuclear power plants, is quite unique in the world. It is expected that by using this guidebook, the quality of nighttime maintenance work and the levels of techniques/skills would be enhanced and maintained, and the safety of workers would be ensured, promoting considerably thus the establishment of a comfortable workplace. (author)

  18. Activation of the ALT pathway for telomere maintenance can affect other sequences in the human genome.

    Science.gov (United States)

    Jeyapalan, Jennie N; Varley, Helen; Foxon, Jenny L; Pollock, Raphael E; Jeffreys, Alec J; Henson, Jeremy D; Reddel, Roger R; Royle, Nicola J

    2005-07-01

    Immortal human cells maintain telomere length by the expression of telomerase or through the alternative lengthening of telomeres (ALT). The ALT mechanism involves a recombination-like process that allows the rapid elongation of shortened telomeres. However, it is not known whether activation of the ALT pathway affects other sequences in the genome. To address this we have investigated, in ALT-expressing cell lines and tumours, the stability of tandem repeat sequences known to mutate via homologous recombination in the human germline. We have shown extraordinary somatic instability in the human minisatellite MS32 (D1S8) in ALT-expressing (ALT+) but not in normal or telomerase-expressing cell lines. The MS32 mutation frequency varied across 15 ALT+ cell lines and was on average 55-fold greater than in ALT- cell lines. The MS32 minisatellite was also highly unstable in three of eight ALT+ soft tissue sarcomas, indicating that somatic destabilization occurs in vivo. The MS32 mutation rates estimated for two ALT+ cell lines were similar to that seen in the germline. However, the internal structures of ALT and germline mutant alleles are very different, indicating differences in the underlying mutation mechanisms. Five other hypervariable minisatellites did not show elevated instability in ALT-expressing cell lines, indicating that minisatellite destabilization is not universal. The elevation of MS32 instability upon activation of the ALT pathway and telomere length maintenance suggests there is overlap between the underlying processes that may be tractable through analysis of the D1S8 locus.

  19. Maintenance Tools applied to Electric Generators to Improve Energy Efficiency and Power Quality of Thermoelectric Power Plants

    Directory of Open Access Journals (Sweden)

    Milton Fonseca Junior

    2017-07-01

    Full Text Available This paper presents a specific method to improve the reliability of the equipment and the quality of power supplied to the electrical systems with the frequency and voltage control of a thermoelectric plant, to guarantee a more stable system. The method has the novelty of combining Total Productive Maintenance (TPM using only four pillars, with Electrical Predictive Maintenance based in failure analysis and diagnostic. It prevents voltage drops caused by excessive reactive consumption, thus guaranteeing the company a perfect functioning of its equipment and providing a longer life of them. The Maintenance Management Program (MMP seeks to prevent failures from causing the equipment to be shut down from the electrical system, which means large financial losses, either by reducing billing or by paying fines to the regulatory agency, in addition to prejudice the reliability of the system. Using management tools, but applying only four TPM pillars, it was possible to achieve innovation in power plants with internal combustion engines. This study aims to provide maintenance with a more reliable process, through the implantation of measurement, control and diagnostic devices, thus allowing the management to reduce breakdown of plant equipment. Some results have been achieved after the implementation, such as reduction of annual maintenance cost, reduction of corrective maintenance, increase of MTBF (Mean Time between Failures and reduction of MTTR (Mean Time to Repair in all areas. Probabilistic models able to describe real processes in a more realistic way, and facilitate the optimization at maximum reliability or minimum costs are presented. Such results are reflected in more reliable and continual power generation.

  20. A virtual reality intervention (Second Life) to improve weight maintenance: Rationale and design for an 18-month randomized trial.

    Science.gov (United States)

    Sullivan, D K; Goetz, J R; Gibson, C A; Mayo, M S; Washburn, R A; Lee, Y; Ptomey, L T; Donnelly, J E

    2016-01-01

    Despite the plethora of weight loss programs available in the US, the prevalence of overweight and obesity (BMI≥25kg/m(2)) among US adults continues to rise at least, in part, due to the high probability of weight regain following weight loss. Thus, the development and evaluation of novel interventions designed to improve weight maintenance are clearly needed. Virtual reality environments offer a promising platform for delivering weight maintenance interventions as they provide rapid feedback, learner experimentation, real-time personalized task selection and exploration. Utilizing virtual reality during weight maintenance allows individuals to engage in repeated experiential learning, practice skills, and participate in real-life scenarios without real-life repercussions, which may diminish weight regain. We will conduct an 18-month effectiveness trial (6 months weight loss, 12 months weight maintenance) in 202 overweight/obese adults (BMI 25-44.9kg/m(2)). Participants who achieve ≥5% weight loss following a 6month weight loss intervention delivered by phone conference call will be randomized to weight maintenance interventions delivered by conference call or conducted in a virtual environment (Second Life®). The primary aim of the study is to compare weight change during maintenance between the phone conference call and virtual groups. Secondarily, potential mediators of weight change including energy and macronutrient intake, physical activity, consumption of fruits and vegetables, self-efficacy for both physical activity and diet, and attendance and completion of experiential learning assignments will also be assessed. Copyright © 2015 Elsevier Inc. All rights reserved.

  1. Proposal of a framework for solving human factors of artificial systems and its application to maintenance work

    International Nuclear Information System (INIS)

    Nagamatsu, Takashi; Otsuji, Tomoo; Yoshikawa, Hidekazu; Shiba, Shigenari

    2004-01-01

    A framework for solving human factors of artificial systems is proposed in this study, where a whole system of machines and the human organization that involves in the operation and management of machines is defined as an 'artificial system'. Five aspects of human factors in the artificial system are first discussed, and the types of artificial system with respect to the human factors are divided into three levels from a viewpoint of complexity. A framework that can treat artificial systems by unified methodology has been proposed for treating both the complexity level and the different kinds of human factors. As a concrete example of this framework application, a prototype system has been developed for advanced plant maintenance support by using ES-HMD (Eye Sensing-Head Mounted Display). This is a remote communication system of cooperative maintenance work between the expert in a remote support center and the maintenance worker at a certain machine in the plant site to conduct a complicated task without committing human error. It was confirmed by laboratory experiment that the expert would instruct the worker so that he or she could perform the task successfully, by observing the worker's eye gazing point and by pointing the right place of action on the transferred display of the worker's eyesight through the ES-MHD. (author)

  2. Maintenance Therapy in Ovarian Cancer with Targeted Agents Improves PFS and OS: A Systematic Review and Meta-Analysis.

    Directory of Open Access Journals (Sweden)

    Xinyu Qian

    Full Text Available Maintenance therapy with targeted agents for prolonging remission for ovarian cancer patients remains controversial. As a result, a meta-analysis was conducted to assess the effectiveness and safety of using maintenance therapy with targeted agents for the treatment of ovarian cancer.From inception to January 2015, we searched for randomized, controlled trials (RCTs using the following databases: PubMed, ScienceDirect, the Cochrane Library, Clinicaltrials.gov and EBSCO. Eligible trials included RCTs that evaluated standard chemotherapy which was either followed or not followed by targeted maintenance in patients with ovarian cancer who had been previously receiving adjunctive treatments, such as cytoreductive surgery and standard chemotherapy. The outcome measures included progression-free survival (PFS, overall survival (OS and incidence of adverse events.A total of 13 RCTs, which were published between 2006 and 2014, were found to be in accordance with our inclusion criteria. The primary meta-analysis indicated that both PFS and OS were statistically and significantly improved in the targeted maintenance therapy group as compared to the control group (PFS: HR = 0.84, 95%CI: 0.75 to 0.95, p = 0.001; OS: HR = 0.91, 95%CI: 0.84 to 0.98, p = 0.02. When taking safety into consideration, the use of targeted agents was significantly correlated with increased risks of fatigue, diarrhea, nausea, vomiting, and hypertension. However, no significant differences were found in incidence rates of abdominal pain, constipation or joint pain.Our results indicate that targeted maintenance therapy clearly improves the survival of ovarian cancer patients but may also increase the incidence of adverse events. Additional randomized, double-blind, placebo-controlled, multicenter investigations will be required on a larger cohort of patients to verify our findings.

  3. Low-dosage epoetin in maintenance haemodialysis: costs and quality-of-life improvement.

    Science.gov (United States)

    Harris, D C

    1994-01-01

    Decisions about epoetin (recombinant human erythropoetin) dosage and target haematocrit in dialysis patients have been determined largely by the high acquisition cost of epoetin, but are made with incomplete knowledge about which target haematocrit gives the optimum clinical benefit. Haematopoietic response to epoetin may be determined by pharmacodynamic factors such as rate and frequency of administration, as well as by individual patient characteristics such as ethnicity. Resistance to epoetin may be due to iron or vitamin deficiency, natural or exogenous inhibitors of erythropoiesis and bone marrow fibrosis. The high acquisition cost of epoetin must be considered along with a number of other factors that can influence the true cost of epoetin treatment. Hidden costs of epoetin treatment include administration costs, changes in other treatments, extra laboratory tests and adverse events. Administration costs and extra laboratory surveillance add little to overall cost. Depletion of iron stores, hypertension, increased blood coagulability and reduced dialyser efficiency resulting from epoetin treatment may all add a small additional component to the true cost. Severe complications with significant cost implications are rare. Amongst the various components of true cost, only the acquisition cost can definitely be reduced by low dosage treatment. Balanced against the true and potential costs of epoetin are a number of benefits which can result in potential savings. The need for blood transfusion is all but abolished, avoiding the cost of transfusion and its complications. Sensitisation against histocompatibility antigens is reduced by avoiding transfusion, and so the waiting time for cadaveric transplantation may be reduced. Rates of hospitalisation for all causes, especially those associated with anaemia, may be reduced by epoetin treatment. By improving well-being, epoetin may allow patients to be transferred to minimal-care units or home where dialysis can be

  4. Improving the turnaround maintenance of the Escravos gas plant / Ishekwene, I.V.

    OpenAIRE

    Ishekwene, Isaac Victor

    2011-01-01

    According to Oliver (2002) the success of turnaround maintenances is measured in terms of the cost of completion, time, safety performance and the performance of the plant afterwards. The Escravos gas plant (EGP) is a gas processing plant that converts associated gas from Chevron owned crude oil wells to liquefied petroleum gas, natural gas and gas condensate (Chevron intranet. Website assessed on September 14, 2007). According to the EGP plant operations coordinator (See inter...

  5. A Human Error Analysis Procedure for Identifying Potential Error Modes and Influencing Factors for Test and Maintenance Activities

    International Nuclear Information System (INIS)

    Kim, Jae Whan; Park, Jin Kyun

    2010-01-01

    Periodic or non-periodic test and maintenance (T and M) activities in large, complex systems such as nuclear power plants (NPPs) are essential for sustaining stable and safe operation of the systems. On the other hand, it also has been raised that human erroneous actions that might occur during T and M activities has the possibility of incurring unplanned reactor trips (RTs) or power derate, making safety-related systems unavailable, or making the reliability of components degraded. Contribution of human errors during normal and abnormal activities of NPPs to the unplanned RTs is known to be about 20% of the total events. This paper introduces a procedure for predictively analyzing human error potentials when maintenance personnel perform T and M tasks based on a work procedure or their work plan. This procedure helps plant maintenance team prepare for plausible human errors. The procedure to be introduced is focusing on the recurrent error forms (or modes) in execution-based errors such as wrong object, omission, too little, and wrong action

  6. Development of advanced human-machine system for plant operation and maintenance

    International Nuclear Information System (INIS)

    Wu, Wei; Ohi, Tadashi; Yoshikawa, Hidekazu; Sawaragi, Tetsuo; Kitamura, Masaharu; Furuta, Kazuo; Gofuku, Akio; Ito, Koji

    2004-01-01

    With the worldwide deregulation of the power industry, and the aging of the nuclear power plants (NPPs), concerns are growing over the reliability and safety of the NPPs, because the regulation of man power may lower the current high level of reliability and safety. In this paper, a concept of overall integrated plant management mechanism is proposed, in order to meet the requirements of cutting costs of NPPs and the requirements of maintaining or increasing safety and reliability. The concept is called as satellite operation maintenance center (SOMC). SOMC integrates the operation and maintenance activities of several NPP units by utilizing advanced information technologies to support cooperation activities between workers allocated at SOMC and the field workers. As for the operation activities, a framework called as Advanced Operation System (AOS) is proposed in this paper. AOS consists of three support sub-systems: dynamic operation permission system(DyOPS), supervisor information presentation system using interface agent, and crew performance evaluation system. As for the maintenance activities, a framework called as Ubiquitous-Computing-based Maintenance support System (UCMS) is proposed next. Two case studies are described, in order to show the way of how UCMS support field workers to do maintenance tasks efficiently, safely, and infallibly as well. Finally, a prospect of SOMC is shown in order to explain the way of how the technology elements developed in this project could be integrated as a whole one system to support maintenance activities of NPPs in the future. (author)

  7. Guidance for the design and management of a maintenance plan to assure safety and improve the predictability of a DOE nuclear irradiation facility. Final report

    International Nuclear Information System (INIS)

    Booth, R.S.; Kryter, R.C.; Shepard, R.L.; Smith, O.L.; Upadhyaya, B.R.; Rowan, W.J.

    1994-10-01

    A program is recommended for planning the maintenance of DOE nuclear facilities that will help safety and enhance availability throughout a facility's life cycle. While investigating the requirements for maintenance activities, a major difference was identified between the strategy suitable for a conventional power reactor and one for a research reactor facility: the latter should provide a high degree of predicted availability (referred to hereafter as ''predictability'') to its users, whereas the former should maximize total energy production. These differing operating goals necessitate different maintenance strategies. A strategy for scheduling research reactor facility operation and shutdown for maintenance must balance safety, reliability,and predicted availability. The approach developed here is based on three major elements: (1) a probabilistic risk analysis of the balance between assured reliability and predictability (presented in Appendix C), (2) an assessment of the safety and operational impact of maintenance activities applied to various components of the facility, and (3) a data base of historical and operational information on the performance and requirements for maintenance of various components. These factors are integrated into a set of guidelines for designing a new highly maintainable facility, for preparing flexible schedules for improved maintenance of existing facilities, and for anticipating the maintenance required to extend the life of an aging facility. Although tailored to research reactor facilities, the methodology has broader applicability and may therefore be used to improved the maintenance of power reactors, particularly in anticipation of peak load demands

  8. Dynamic optimization of maintenance and improvement planning for water main system: Periodic replacement approach

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Jong Woo; Choi, Go Bong; Lee, Jong Min [Seoul National University, Seoul (Korea, Republic of); Suh, Jung Chul [Samchully Corporation, Seoul (Korea, Republic of)

    2016-01-15

    This paper proposes a Markov decision process (MDP) based approach to derive an optimal schedule of maintenance, rehabilitation and replacement of the water main system. The scheduling problem utilizes auxiliary information of a pipe such as the current state, cost, and deterioration model. The objective function and detailed algorithm of dynamic programming are modified to solve the periodic replacement problem. The optimal policy evaluated by the proposed algorithm is compared to several existing policies via Monte Carlo simulations. The proposed decision framework provides a systematic way to obtain an optimal policy.

  9. Reliability and Maintainability Model (RAM): User and Maintenance Manual. Part 2; Improved Supportability Analysis

    Science.gov (United States)

    Ebeling, Charles E.

    1996-01-01

    This report documents the procedures for utilizing and maintaining the Reliability & Maintainability Model (RAM) developed by the University of Dayton for the National Aeronautics and Space Administration (NASA) Langley Research Center (LaRC). The purpose of the grant is to provide support to NASA in establishing operational and support parameters and costs of proposed space systems. As part of this research objective, the model described here was developed. This Manual updates and supersedes the 1995 RAM User and Maintenance Manual. Changes and enhancements from the 1995 version of the model are primarily a result of the addition of more recent aircraft and shuttle R&M data.

  10. Time since injury limits but does not prevent improvement and maintenance of gains in balance in chronic stroke.

    Science.gov (United States)

    Llorens, Roberto; Noé, Enrique; Alcañiz, Mariano; Deutsch, Judith E

    2018-01-01

    To determine the influence of time since injury on the efficacy and maintenance of gains of rehabilitation of balance after stroke. Forty-seven participants were assigned to a least (6-12 months), a moderate (12-24 months), or a most chronic (>24 months) group. Participants trained for 20 one-hour sessions, administered three to five times a week, combining conventional physical therapy and visual feedback-based exercises that trained the ankle and hip strategies. Participants were assessed before, after the intervention, and one month later with a posturography test (Sway Speed and Limits of Stability) and clinical scales. In contrast to other subjects, the most chronic participants failed to improve their sway and to maintain the benefits detected in the Limits of Stability after the intervention. Although all the participants improved in those clinical tests that better matched the trained skills, time since injury limited the improvement, and over all, the maintenance of gains. Time since injury limits but does not prevent improvement in chronic stages post-stroke, and this effect appears to be more pronounced with maintaining gains. These findings support that training duration and intensity as well as type of therapy may need to be adjusted based on time post-stroke.

  11. How and when will self-assessment improve maintenance of CANDU plants - evaluator's view

    Energy Technology Data Exchange (ETDEWEB)

    Mika, K. [Ontario Hydro. Bruce Nuclear Station. Tiverton, ON (Canada)

    1997-07-01

    Learning organizations use self-evaluation programs to compare their actual performance with their management's expectations and industry standards. In general, self-evaluations identify areas needing improvement. Self-evaluation activities in maintenance departments include self-assessments, management monitoring observations, root cause analyses, event investigations, benchmarking, use of operating experience, self-checking, and problem reporting systems. In Ontario Hydro Nuclear (OHN) we have used almost all forms of self-evaluation with mixed success. However, we did not use self-assessments. With emphasis on excellent maintenance this powerful form of self-evaluation is being introduced to all our plants. Because of its recency and relative inexperience with it, this paper is focused on self-assessment. The paper provides the author's perspective on how a self-assessment program would be evaluated by an independent internal evaluation and what attributes should be in place in order for maintenance departments to succeed in the implementation and successful continuation of the program. (author)

  12. Application of an integrated risk management system for improved maintenance in industrial plants

    Energy Technology Data Exchange (ETDEWEB)

    Jovanovic, A.; Balos, D.T.; Vinod, G.; Balos, D. [Steinbeis Advanced Risk Technologies, Stuttgart (Germany); Stanojevic, P. [NIS - Petroleum Industry of Serbia, Novi Sad (Serbia)

    2007-06-15

    The paper presents the application of the Integrated Risk Management System (iRiS) and its application to the areas of Risk Based Inspection (RBI), Reliability Centered Maintenance (RCM), Root Cause Failure Analysis (RCFA) and Health, Safety and Environment (HSE). The web-based system integrates also the aspects of risk management related to data acquisition and management and interactive reporting and controlled use of single parts of the system by various individual users and/or user levels. A complementing part of the system is a tool for project management including the documentation and activity management, as well as scheduling and e-education and e-training. The complementing parts of the system are the CMMS part (maintenance management), the extension of HSE to HSSE (including the 'security' aspects and providing links to the disaster management system) and further interfacing towards general management system and process modeling and management systems. Experiences from the applications of system in Hungary (at over 60 units) and in Serbia, for several refineries and further units in upstream and downstream, are presented in the paper. (orig.)

  13. An experimental study on the effect of noise and sleep loss on human performance using the measure of TCI during NPP maintenance

    Energy Technology Data Exchange (ETDEWEB)

    Jo, Hyun Jun

    2008-02-15

    There are various stressors in NPP maintenance, such as environmental stressors and work-related stressors. These stressors degrade human performance and increase human error. Stress has not been largely considered as a factor of human error in root cause analyses. Recently, however, regulatory bodies and research institutes have worked to manage the physical condition of the operator and improve the environment and methods of NPP maintenance. These efforts have focused on reducing the incidence of human error due to stress. It is necessary to study how much stress affects human performance before these efforts are complete. The objectives of the present study are to formulate a Task Concentration Index (TCI) based on Electrocardiogram (ECG) signals in order to evaluate the degree to which a person concentrates on a task experimentally. With the TCI, the study will also evaluate the effects of noise and sleep loss on human performance during NPP maintenance tasks. Stress influences the efficiency of information processing and data input and output. Stress and human error are tightly linked in a closed-loop combination. The human body responds to stress by activating the nervous system and specific hormones. Therefore, physiological signals are changed by stress. A spectral analysis of Heart Rate Variability (HRV) provides a noninvasive technique for indirectly measuring sympathetic and parasympathetic modulation during specific tasks. The high-frequency component (HF, 0.15∼0.4Hz) reflects momentary respiration and is mediated by the parasympathetic nervous system. The low-frequency component (LF, 0.04∼0.15Hz) has been interpreted mainly as an indicator of sympathetic influences (especially when expressed in normalized units). When the level of stress is high, the Normalized Low Frequency component (NoLF) of HRV signals is generally higher than the normal state. The difference in NoLF readings between a normal state and during a task could be used to evaluate

  14. An experimental study on the effect of noise and sleep loss on human performance using the measure of TCI during NPP maintenance

    International Nuclear Information System (INIS)

    Jo, Hyun Jun

    2008-02-01

    There are various stressors in NPP maintenance, such as environmental stressors and work-related stressors. These stressors degrade human performance and increase human error. Stress has not been largely considered as a factor of human error in root cause analyses. Recently, however, regulatory bodies and research institutes have worked to manage the physical condition of the operator and improve the environment and methods of NPP maintenance. These efforts have focused on reducing the incidence of human error due to stress. It is necessary to study how much stress affects human performance before these efforts are complete. The objectives of the present study are to formulate a Task Concentration Index (TCI) based on Electrocardiogram (ECG) signals in order to evaluate the degree to which a person concentrates on a task experimentally. With the TCI, the study will also evaluate the effects of noise and sleep loss on human performance during NPP maintenance tasks. Stress influences the efficiency of information processing and data input and output. Stress and human error are tightly linked in a closed-loop combination. The human body responds to stress by activating the nervous system and specific hormones. Therefore, physiological signals are changed by stress. A spectral analysis of Heart Rate Variability (HRV) provides a noninvasive technique for indirectly measuring sympathetic and parasympathetic modulation during specific tasks. The high-frequency component (HF, 0.15∼0.4Hz) reflects momentary respiration and is mediated by the parasympathetic nervous system. The low-frequency component (LF, 0.04∼0.15Hz) has been interpreted mainly as an indicator of sympathetic influences (especially when expressed in normalized units). When the level of stress is high, the Normalized Low Frequency component (NoLF) of HRV signals is generally higher than the normal state. The difference in NoLF readings between a normal state and during a task could be used to evaluate

  15. Improvement of the availability of nuclear power station maintenance teleprocessing; Amelioration de la disponibilite des teletraitements de maintenance des centrales nucleaires

    Energy Technology Data Exchange (ETDEWEB)

    Badellon, D; Bloton, Y; Bres, J P; Cuche, A; Trabaud, C

    1993-11-01

    The Data processing department at the DEPT manages a centralized maintenance application for the nineteen power plants in France. This application performs fourteen million CICS transactions every month, passing through the Electricite de France national teleprocessing network. Operation is split among two IBM 9021 computer partitions located one hundred kilometres apart for backup and security reasons in the two computer centres of the STI (EDF Data Processing Department) and the R and DD (EDF Research and Development Department). The CICS are stopped each night at 10.30 so that the data bases can be backed up onto cassettes and so that the work from the plants can be processed in batches. The plants update the number of bases and extract subsets intended for the plants. From the outset, considerable resources were assigned to this operation: cassette insertion robots, a high-power batch processing scheduling and planning tool optimizing parallel step work, high-power computers: two IBM 3090-40J computers were dedicated to this application as early as 1989. However, the buildup and evolution of this application led to ever greater basic volumes and increasingly voluminous and complex batch processing, leading to reduced transactional availability by pushing back the startup times. To combat this trend, the Data Processing Department at the DEPT, together with the Departments operating the computers, took a number of steps to speed up batch processing and thus improve teleprocessing availability. In particular, on the partition operated by the computer Centre in the Applied Mathematics and Data Processing Service of the Research and Development Department at EDF, a number of studies were conducted, as described in the following text. This description comprises three parts: - report on the studies and steps taken, both from the hardware and the software viewpoint; - an evaluation of their effectiveness and the results obtained; - the new areas for study selected.

  16. Augmented reality for improved communication of construction and maintenance plans in nuclear power plants

    International Nuclear Information System (INIS)

    Sorensen, Soren S.

    2010-01-01

    The purpose of implementing Augmented Reality, AR, in the planning, construction and maintenance of Nuclear Power Plants is to secure strict control, precise and correct constructions, exact execution of assignments and heightened safety at all levels. Communication of construction plans to ensure precise and correct assembly of structural elements is essential in all building projects. This is especially crucial in the construction of nuclear plants and installation of new components. The current ways in which construction plans are communicated, blueprints, 3D digital models and written descriptions all embody the need for significant levels of abstraction and interpretation, and are thus both difficult to understand and can lead to misinterpretations. A simulation system with full scale three dimensional models experienced in the physical setting where operations are to take place would bring operators closer to the real life assignments. Augmented Reality is a visualization technology that provides this motivation. (author)

  17. Improving linear transport infrastructure efficiency by automated learning and optimised predictive maintenance techniques (INFRALERT)

    Science.gov (United States)

    Jiménez-Redondo, Noemi; Calle-Cordón, Alvaro; Kandler, Ute; Simroth, Axel; Morales, Francisco J.; Reyes, Antonio; Odelius, Johan; Thaduri, Aditya; Morgado, Joao; Duarte, Emmanuele

    2017-09-01

    The on-going H2020 project INFRALERT aims to increase rail and road infrastructure capacity in the current framework of increased transportation demand by developing and deploying solutions to optimise maintenance interventions planning. It includes two real pilots for road and railways infrastructure. INFRALERT develops an ICT platform (the expert-based Infrastructure Management System, eIMS) which follows a modular approach including several expert-based toolkits. This paper presents the methodologies and preliminary results of the toolkits for i) nowcasting and forecasting of asset condition, ii) alert generation, iii) RAMS & LCC analysis and iv) decision support. The results of these toolkits in a meshed road network in Portugal under the jurisdiction of Infraestruturas de Portugal (IP) are presented showing the capabilities of the approaches.

  18. Effect of cAMP derivates on assembly and maintenance of tight junctions in human umbilical vein endothelial cells

    Directory of Open Access Journals (Sweden)

    Beese Michaela

    2010-09-01

    Full Text Available Abstract Background Endothelial tight and adherens junctions control a variety of physiological processes like adhesion, paracellular transport of solutes or trafficking of activated leukocytes. Formation and maintenance of endothelial junctions largely depend on the microenvironment of the specific vascular bed and on interactions of the endothelium with adjacent cell types. Consequently, primary cultures of endothelial cells often lose their specific junctional pattern and fail to establish tight monolayer in vitro. This is also true for endothelial cells isolated from the vein of human umbilical cords (HUVEC which are widely used as model for endothelial cell-related studies. Results We here compared the effect of cyclic 3'-5'-adenosine monophosphate (cAMP and its derivates on formation and stabilization of tight junctions and on alterations in paracellular permeability in HUVEC. We demonstrated by light and confocal laser microscopy that for shorter time periods the sodium salt of 8-bromoadenosine-cAMP (8-Br-cAMP/Na and for longer incubation periods 8-(4-chlorophenylthio-cAMP (pCPT-cAMP exerted the greatest effects of all compounds tested here on formation of continuous tight junction strands in HUVEC. We further demonstrated that although all compounds induced protein kinase A-dependent expression of the tight junction proteins claudin-5 and occludin only pCPT-cAMP slightly enhanced paracellular barrier functions. Moreover, we showed that pCPT-cAMP and 8-Br-cAMP/Na induced expression and membrane translocation of tricellulin. Conclusions pCPT-cAMP and, to a lesser extend, 8-Br-cAMP/Na improved formation of continuous tight junction strands and decreased paracellular permeability in primary HUVEC. We concluded that under these conditions HUVEC represent a feasible in vitro model to study formation and disassembly of endothelial tight junctions and to characterize tight junction-associated proteins

  19. Advanced maintenance research programs

    International Nuclear Information System (INIS)

    Marston, T.U.; Gelhaus, F.; Burke, R.

    1985-01-01

    The purpose of this paper is to provide the reader with an idea of the advanced maintenance research program at the Electric Power Research Institute (EPRI). A brief description of the maintenance-related activities is provided as a foundation for the advanced maintenance research projects. The projects can be divided into maintenance planning, preventive maintenance program development and implementation, predictive (or conditional) maintenance, and innovative maintenance techniques. The projects include hardware and software development, human factors considerations, and technology promotion and implementation. The advanced concepts include: the incorporation of artificial intelligence into outage planning; turbine and pump maintenance; rotating equipment monitoring and diagnostics with the aid of expert systems; and the development of mobile robots for nuclear power plant maintenance

  20. Improvement of robustness of optical see-through AR for a remote maintenance support system

    International Nuclear Information System (INIS)

    Nagamatsu, Takashi; Kaieda, Yohei; Kitagawa, Yuki; Shimada, Hiroyuki; Otsuji, Tomoo; Yoshikawa, Hidekazu

    2005-01-01

    A remote maintenance support system using optical see-through AR has been developed to keep safety and reliability in preparation for old experts' retirement. It enables plant workers to collaborate with a remote expert (supervisor) by using a wearable computer, an optical see-through AR (Augmented Reality) technology and eye-gaze information. The optical see-through AR enables a user to see the real world through a transparent display and it contributes to keeping safety of plant workers and acquiring detail information of machines. On the contrary, the registration between computer-generated objects and the real world is difficult, so we developed a method to correct the geometrical consistency for practical use of optical see-through AR. The developed method has two steps: (1) detection of the shift amount of HMD by the eye camera image and (2) adjustment of the display position on the HMD screen. This method made it possible to allow user's moving and physical shift of HMD, so it is capable of wide application to practical works

  1. Advanced diagnostics and predictive maintenance to improve availability and reliability of ENEL plants

    Energy Technology Data Exchange (ETDEWEB)

    Cenci, V.; Ghironi, M.; Guidi, L.; Lauro, M.; Pestonesi, D. [ENEL (Italy). Generation and Energy Management Division

    2007-07-01

    This paper reviews the ENEL Generation and Energy Management strategy for diagnostics and predictive maintenance of power plants and provides a comprehensive description of effective applications and systems. Exploiting the most advanced information and communication technologies makes it possible to capture weak and hidden signals and powerful processing can be used to discover forewarning symptoms and identify anomalies both in the process and, above all, inside the devices. The following systems and applications are presented together with results and impact on plant profitability: expert system for the diagnostics of plant main machinery; advanced diagnostics of 'intelligent' fieldbus devices such as on/off valve motor-driven actuators, control-valve positioners and pneumatic actuators, transmitters; control loop and control valve diagnostics in order to investigate valve friction with an estimation of the residual time to failure; multisensorial diagnostics for coal transport and storage systems aimed at preventing firing and structural damages; and wireless sensor networks for the diagnostics of medium and small size components. 4 refs., 14 figs., 1 tab.

  2. Emergence and maintenance of menopause in humans: A game theory model.

    Science.gov (United States)

    Thouzeau, Valentin; Raymond, Michel

    2017-10-07

    Menopause, the permanent cessation of ovulation, occurs in women well before the end of their expected life span. Several adaptive hypotheses have been proposed to solve this evolutionary puzzle, each based on a possible fitness benefit derived from an early reproductive senescence, but no consensus has emerged. The construction of a game theory model allowed us to jointly study the main adaptive hypotheses in emergence and maintenance of menopause. Four classical hypotheses on the benefits of menopause were considered (decreased maternal mortality, increased grandmothering, decreased conflict over reproductive resources between older and younger females, and changes in their relatedness) plus a fifth one derived from a possible pleiotropic trade-off. Interestingly, the conditions for the emergence of menopause are more restrictive than those for its maintenance due to the social and familial changes induced by the occurrence of non-reproductive older women. Copyright © 2017 Elsevier Ltd. All rights reserved.

  3. Involvement of DNA repair in telomere maintenance and chromosomal instability in human cells

    International Nuclear Information System (INIS)

    Ayouaz, Ali

    2008-01-01

    Telomeres are a major actor of cell immortalization, precursor of a carcinogenesis process. Thus, it appears that the maintenance of telomeres is crucial in the implementation of carcinogenesis process. Due to their structures and under some conditions, telomeres can be assimilated in some respects to chromosomal breakages. Within this perspective, this research thesis aims at determining under which circumstances telomeres can be taken as targets by DNA repair mechanisms. More precisely, the author addressed the respective contributions of two repair mechanisms (the Non-Homologous End-Joining or NHEJ, and Homologous Recombination or HR) in the maintenance of telomere integrity. The author first discusses knowledge related to the interaction between chromosomal extremities and repair mechanisms. Then, he defines the behaviour of these mechanisms with respect to telomeres. He shows that, in absence of recombination mechanisms, the integrity of telomeres is not affected. Finally, he reports the attempt to determine their respective contributions in telomeric homeostasis [fr

  4. Human-Technology Centric In Cyber Security Maintenance For Digital Transformation Era

    Science.gov (United States)

    Ali, Firkhan Ali Bin Hamid; Zalisham Jali, Mohd, Dr

    2018-05-01

    The development of the digital transformation in the organizations has become more expanding in these present and future years. This is because of the active demand to use the ICT services among all the organizations whether in the government agencies or private sectors. While digital transformation has led manufacturers to incorporate sensors and software analytics into their offerings, the same innovation has also brought pressure to offer clients more accommodating appliance deployment options. So, their needs a well plan to implement the cyber infrastructures and equipment. The cyber security play important role to ensure that the ICT components or infrastructures execute well along the organization’s business successful. This paper will present a study of security management models to guideline the security maintenance on existing cyber infrastructures. In order to perform security model for the currently existing cyber infrastructures, combination of the some security workforces and security process of extracting the security maintenance in cyber infrastructures. In the assessment, the focused on the cyber security maintenance within security models in cyber infrastructures and presented a way for the theoretical and practical analysis based on the selected security management models. Then, the proposed model does evaluation for the analysis which can be used to obtain insights into the configuration and to specify desired and undesired configurations. The implemented cyber security maintenance within security management model in a prototype and evaluated it for practical and theoretical scenarios. Furthermore, a framework model is presented which allows the evaluation of configuration changes in the agile and dynamic cyber infrastructure environments with regard to properties like vulnerabilities or expected availability. In case of a security perspective, this evaluation can be used to monitor the security levels of the configuration over its lifetime and

  5. Engineering, maintenance, and initiatives to improve LAMPF beam availability and system reliability

    International Nuclear Information System (INIS)

    Harris, H.W.; DeHaven, R.A.; Hart, V.E.; Parsons, W.M.; Sturrock, J.C.

    1992-01-01

    Two different requirements are driving engineering studies and hardware development to improve LAMPF. The first is concerned with component and system improvements to increase beam availability during the LAMPF production cycle. Hardware changes in RF, power supplies, and magnets are being implemented to increase mean time between failure and reduce time to replace or repair failed units. A joint LAMPF-Industry project is on-going to improve reliability of RF components. A component test stand is being refurbished to include significant development capability. The second approach includes several changes that will increase the duty factor of the existing accelerator. Major changes are being evaluated for replacing the front end of the accelerator. Other changes improving the high brightness capability could result in a new performance plateau for LAMPF. 2 refs., 2 figs

  6. Engineering, maintenance, and new initiatives to improve LAMPF beam availability and system reliability

    International Nuclear Information System (INIS)

    Harris, H.W.; DeHaven, R.A.; Hart, V.E.; Parsons, W.M.; Sturrock, J.C.

    1992-01-01

    Two different requirements are driving engineering studies and hardware development to improve LAMPF. The first is concerned with component and system improvements to increase beam availability during the LAMPF production cycle. Hardware changes in RF, power supplies, and magnets are being implemented to increase mean time between failure and reduce time to replace or repair failed units. A joint LAMPF-Industry project is on-going to improve reliability of RF components. A component test stand is being refurbished to include significant development capability. The second approach includes several changes that will increase the duty factor of the existing accelerator. Major changes are being evaluated for replacing the front end of the accelerator. Other changes improving high brightness capability could result in a new performance plateau for LAMPF

  7. Improving Naval Aviation Maintenance Quality Management Processes at the Organizational Maintenance Level: The Influences of the International Standards Organization (ISO) 9000 Quality Management System on the Naval Aviation Maintenance Program (NAMP)

    National Research Council Canada - National Science Library

    Couch, Christopher

    1999-01-01

    ... to make them consistent with the ISO 9000 QMS. The NAMP is Naval aviation's overall guiding document that outlines command, administrative, and management relationships, and assigns maintenance policy and procedure responsibilities...

  8. Development of a Field Management Standard for Improving Human Factors

    International Nuclear Information System (INIS)

    Yun, Young Su; Son, Il Moon; Son, Byung Chang; Kwak, Hyo Yean

    2009-07-01

    This project is to develop a management guideline for improving human performances as a part of the Human Factors Management System of Kori unit 1 which is managing all of human factors items such as man-machine system interfaces, work procedures, work environments, and human reliabilities in nuclear power plants. Human factors engineering includes an human factors suitability analysis and improvement of human works, an analysis of accidents by human error, an improvement of work environment, an establishment of human factors management rules and a development of human resources to manage and perform those things consistently. For assisting these human factors engineering tasks, we developed human factors management guidelines, checklists and work procedures to be used in staffing, qualification, training, and human information requirements and workload. We also provided a software tool for managing the above items. Additionally, contents and an item pool for a human factors qualifying examination and training programs were developed. A procedures improvement and a human factors V and V on the Kori unit 1 have been completed as a part of this project, too

  9. Stable isotopes for improving human nutrition

    International Nuclear Information System (INIS)

    Uauy, Ricardo

    2001-01-01

    , e.g., vitamin A, iron and zinc nutrition. Copper deficit and excess also have important implications for human health. Here, isotopic methods for measuring absorption, storage and excretion permit a more precise definition of the range of exposures that are tolerated without adverse effects. The mandate of IAEA to support national governments, UN agencies and others in using nuclear procedures to monitor the impact of interventions, demographic change and development is being served by regional technical cooperation projects in Latin America, Africa and Asia. Building local capacity has been incorporated in the process, establishing networks to support local programs, training activities, and laboratories. These efforts will serve applied researchers and planners who need the practical applications of novel methodologies to improve nutrition and the well being of underserved populations world-wide. (author)

  10. Improvement of availability of PWR nuclear plants through the reduction of the time required for refueling/maintenance outages

    International Nuclear Information System (INIS)

    Mayers, J.B.; Soth, L.G.

    1978-04-01

    The objective of the project, conducted by Commonwealth Research Corporation and Westinghouse Electric Corporation, is to identify improvements in procedures and equipment which will reduce the time required for refueling/maintenance outages at PWR nuclear power plants. The outage of Commonwealth Edison Zion Station Unit 1 in March through May of 1976 was evaluated to identify those items which caused delays and those work activities that offer the potential for significant improvements that could reduce the overall duration of the outage and achieve an improvement in the plant's availability for power production. Modifications in procedures have been developed and were evaluated during one or more outages in 1977. Conceptual designs have been developed for equipment modifications to the refueling system that could reduce the time required for the refueling portion of the outage. The purpose of the interim report is to describe those conceptual designs and to assess their impact upon future outages. Recommendations are included for the implementation of these equipment improvements in a continuation of this program as a demonstration of plant availability benefits that can be realized in PWR nuclear plants already in operation or under construction

  11. The role of NF-κB signaling in the maintenance of pluripotency of human induced pluripotent stem cells.

    Directory of Open Access Journals (Sweden)

    Osamu Takase

    Full Text Available NF-κB signaling plays an essential role in maintaining the undifferentiated state of embryonic stem (ES cells. However, opposing roles of NF-κB have been reported in mouse and human ES cells, and the role of NF-κB in human induced pluripotent stem (iPS cells has not yet been clarified. Here, we report the role of NF-κB signaling in maintaining the undifferentiated state of human iPS cells. Compared with differentiated cells, undifferentiated human iPS cells showed an augmentation of NF-κB activity. During differentiation induced by the removal of feeder cells and FGF2, we observed a reduction in NF-κB activity, the expression of the undifferentiation markers Oct3/4 and Nanog, and the up-regulation of the differentiated markers WT-1 and Pax-2. The specific knockdown of NF-κB signaling using p65 siRNA also reduced the expression of Oct3/4 and Nanog and up-regulated WT-1 and Pax-2 but did not change the ES-like colony formation. Our results show that the augmentation of NF-κB signaling maintains the undifferentiated state of human iPS and suggest the importance of this signaling pathway in maintenance of human iPS cells.

  12. The human factor in operation and maintenance of complex high-reliability systems

    International Nuclear Information System (INIS)

    Ryan, T.G.

    1989-01-01

    Human factors issues in probabilistic risk assessment (PRAs) of complex high-reliability systems are addressed. These PRAs influence system operation and technical support programs such as maintainability, test, and surveillance. Using the U.S. commercial nuclear power industry as the setting, the paper addresses the manner in which PRAs currently treat human performance, the state of quantification methods and source data for analyzing human performance, and the role of human factors specialist in the analysis. The paper concludes with a presentation of TALENT, an emerging concept for fully integrating broad-based human factors expertise into the PRA process, is presented. 47 refs

  13. DNMT1 but not its interaction with the replication machinery is required for maintenance of DNA methylation in human cells

    Science.gov (United States)

    Spada, Fabio; Haemmer, Andrea; Kuch, David; Rothbauer, Ulrich; Schermelleh, Lothar; Kremmer, Elisabeth; Carell, Thomas; Längst, Gernot; Leonhardt, Heinrich

    2007-01-01

    DNA methylation plays a central role in the epigenetic regulation of gene expression in vertebrates. Genetic and biochemical data indicated that DNA methyltransferase 1 (Dnmt1) is indispensable for the maintenance of DNA methylation patterns in mice, but targeting of the DNMT1 locus in human HCT116 tumor cells had only minor effects on genomic methylation and cell viability. In this study, we identified an alternative splicing in these cells that bypasses the disrupting selective marker and results in a catalytically active DNMT1 protein lacking the proliferating cell nuclear antigen–binding domain required for association with the replication machinery. Using a mechanism-based trapping assay, we show that this truncated DNMT1 protein displays only twofold reduced postreplicative DNA methylation maintenance activity in vivo. RNA interference–mediated knockdown of this truncated DNMT1 results in global genomic hypomethylation and cell death. These results indicate that DNMT1 is essential in mouse and human cells, but direct coupling of the replication of genetic and epigenetic information is not strictly required. PMID:17312023

  14. Program integration of predictive maintenance with reliability centered maintenance

    International Nuclear Information System (INIS)

    Strong, D.K. Jr; Wray, D.M.

    1990-01-01

    This paper addresses improving the safety and reliability of power plants in a cost-effective manner by integrating the recently developed reliability centered maintenance techniques with the traditional predictive maintenance techniques of nuclear power plants. The topics of the paper include a description of reliability centered maintenance (RCM), enhancing RCM with predictive maintenance, predictive maintenance programs, condition monitoring techniques, performance test techniques, the mid-Atlantic Reliability Centered Maintenance Users Group, test guides and the benefits of shared guide development

  15. Human Resource Management for Continuous Improvement

    DEFF Research Database (Denmark)

    Jørgensen, Frances; Boer, Harry; Laugen, Bjørge

    2006-01-01

    The objective of this paper is to investigate the relationship between HRM practices and Continuous Improvement (CI) activities in order to gain an understanding of how the HRM function may be utilized to improve CI implementation success, and consequently, organizational performance. The paper i...

  16. Improving Safety through Human Factors Engineering.

    Science.gov (United States)

    Siewert, Bettina; Hochman, Mary G

    2015-10-01

    Human factors engineering (HFE) focuses on the design and analysis of interactive systems that involve people, technical equipment, and work environment. HFE is informed by knowledge of human characteristics. It complements existing patient safety efforts by specifically taking into consideration that, as humans, frontline staff will inevitably make mistakes. Therefore, the systems with which they interact should be designed for the anticipation and mitigation of human errors. The goal of HFE is to optimize the interaction of humans with their work environment and technical equipment to maximize safety and efficiency. Special safeguards include usability testing, standardization of processes, and use of checklists and forcing functions. However, the effectiveness of the safety program and resiliency of the organization depend on timely reporting of all safety events independent of patient harm, including perceived potential risks, bad outcomes that occur even when proper protocols have been followed, and episodes of "improvisation" when formal guidelines are found not to exist. Therefore, an institution must adopt a robust culture of safety, where the focus is shifted from blaming individuals for errors to preventing future errors, and where barriers to speaking up-including barriers introduced by steep authority gradients-are minimized. This requires creation of formal guidelines to address safety concerns, establishment of unified teams with open communication and shared responsibility for patient safety, and education of managers and senior physicians to perceive the reporting of safety concerns as a benefit rather than a threat. © RSNA, 2015.

  17. An improved silhouette for human pose estimation

    Science.gov (United States)

    Hawes, Anthony H.; Iftekharuddin, Khan M.

    2017-08-01

    We propose a novel method for analyzing images that exploits the natural lines of a human poses to find areas where self-occlusion could be present. Errors caused by self-occlusion cause several modern human pose estimation methods to mis-identify body parts, which reduces the performance of most action recognition algorithms. Our method is motivated by the observation that, in several cases, occlusion can be reasoned using only boundary lines of limbs. An intelligent edge detection algorithm based on the above principle could be used to augment the silhouette with information useful for pose estimation algorithms and push forward progress on occlusion handling for human action recognition. The algorithm described is applicable to computer vision scenarios involving 2D images and (appropriated flattened) 3D images.

  18. Improvements to executive function during exercise training predict maintenance of physical activity over the following year

    Directory of Open Access Journals (Sweden)

    John eBest

    2014-05-01

    Full Text Available Previous studies have shown that exercise training benefits cognitive, neural, and physical health markers in older adults. It is likely that these positive effects will diminish if participants return to sedentary lifestyles following training cessation. Theory posits that that the neurocognitive processes underlying self-regulation, namely executive function (EF, are important to maintaining positive health behaviors. Therefore, we examined whether better EF performance in older women would predict greater adherence to routine physical activity (PA over 1 year following a 12-month resistance exercise training randomized controlled trial. The study sample consisted of 125 community-dwelling women aged 65 to 75 years old. Our primary outcome measure was self-reported PA, as measured by the Physical Activity Scale for the Elderly (PASE, assessed on a monthly basis from month 13 to month 25. Executive function was assessed using the Stroop Test at baseline (month 0 and post-training (month 12. Latent growth curve analyses showed that, on average, PA decreased during the follow-up period but at a decelerating rate. Women who made greater improvements to EF during the training period showed better adherence to PA during the 1-year follow-up period (β = -.36, p .10. Overall, these findings suggest that improving EF plays an important role in whether older women maintain higher levels of PA following exercise training and that this association is only apparent after training when environmental support for PA is low.

  19. Human Resource Management for Continuous Improvement

    DEFF Research Database (Denmark)

    Jørgensen, Frances; Laugen, Bjørge Timenes; Boer, Harry

    2007-01-01

    This paper investigates the relationship between HRM practices and Continuous Improvement (CI) activities in order to gain an understanding of how the HRM function may be utilized to improve CI implementation success, and consequently, company performance. The paper begins with a brief review...... of the HRM and CI literature and then presents statistical analyses of data collected from the Continuous Improvement Network Survey (2003), which demonstrate that HRM has a significant effect on CI behaviour and company performance, with the strongest relationship between HRM, CI and performance occurring...

  20. A randomized trial using motivational interviewing for maintenance of blood pressure improvements in a community-engaged lifestyle intervention: HUB city steps

    Science.gov (United States)

    Landry, Alicia; Madson, Michael; Thomson, Jessica; Zoellner, Jamie; Connell, Carol; Yadrick, Kathleen

    2015-01-01

    Little is known about the effective dose of motivational interviewing for maintaining intervention-induced health outcome improvements. The purpose of this study was to compare effects of two doses of motivational interviewing for maintaining blood pressure improvements in a community-engaged lifestyle intervention conducted with African-Americans. Participants were tracked through a 12-month maintenance phase following a 6-month intervention targeting physical activity and diet. For the maintenance phase, participants were randomized to receive a low (4) or high (10) dose of motivational interviewing delivered via telephone by trained research staff. Generalized linear models were used to test for group differences in blood pressure. Blood pressure significantly increased during the maintenance phase. No differences were apparent between randomized groups. Results suggest that 10 or fewer motivational interviewing calls over a 12-month period may be insufficient to maintain post-intervention improvements in blood pressure. Further research is needed to determine optimal strategies for maintaining changes. PMID:26590242

  1. Maintenance work management system

    International Nuclear Information System (INIS)

    Kanai, T.; Takahashi, Y.; Takahashi, K.; Nishino, M.; Takeshige, R.

    2000-01-01

    The maintenance work management system supports the efficient drawing up of various documents for the maintenance work at nuclear power stations and the speeding up of the permission procedure. In addition, it improves the quality assurance of the safety and reliability of the maintenance work. Key merits of the system are: 1. Efficiently drawing up various documents for the maintenance work by using the stored data for the previous maintenance work and the pipe and instrument diagram (P and ID) data. 2. Supporting the management work for the completion of maintenance work safety by using the isolation information stored on the computer system. 3. Speeding up the permission procedure by electronic mail and electronic permission. 4. Displaying additional information such as the specifications of equipment, maintenance result, and maintenance plan by linking up with the database of another system. 5. Reducing the cost of hardware devices by using client/server network configurations of personal computers and a personal computer server. (author)

  2. Human Reliability Analysis. Applicability of the HRA-concept in maintenance shutdown; Analys av maensklig tillfoerlitlighet. HRA-begreppets tillaempbarhet vid revisionsavstaellning

    Energy Technology Data Exchange (ETDEWEB)

    Obenius, Aino (MTO Psykologi AB, Stockholm (SE))

    2007-08-15

    Probabilistic Safety Analysis (PSA) is performed for Swedish nuclear power plants in order to make predictions and improvements of system safety. The analysis of the Three Mile Island and Chernobyl accidents contributed to broaden the approach to nuclear power plant safety. A system perspective focusing on the interaction between aspects of Man, Technology and Organization (MTO) emerged in addition to the development of Human Factors knowledge. To take the human influence on the technical system into consideration when performing PSAs, a Human Reliability Analysis (HRA) is performed. PSA is performed for different stages and plant operating states, and the current state of Swedish analyses is Low power and Shutdown (LPSD), also called Shutdown PSA (SPSA). The purpose of this master's thesis is to describe methods and basic models used when analysing human reliability for the LPSD state. The following questions are at issue: 1. How can the LPSD state be characterised and defined? 2. What is important to take into consideration when performing a LPSD HRA? 3. How can human behaviour be modelled for a LPSD risk analysis? 4. According to available empirical material, how are the questions above treated in performed analysis of human operation during LPSD? 5. How does the result of the questions above affect the way methods for analysis of LPSD could and/or should be developed? The procedure of this project has mainly consisted of literature studies of available theory for modelling of human behaviour and risk analysis of the LPSD state. This study regards analysis of planned outages when maintenance, fuel change, tests and inspections are performed. The outage period is characterised by planned maintenance activities performed in rotating 3-shifts, around the clock, as well as many of the persons performing work tasks on the plant being external contractors. The working conditions are characterised by stress due to heat, radiation and physically demanding or

  3. Resistant starch: promise for improving human health.

    Science.gov (United States)

    Birt, Diane F; Boylston, Terri; Hendrich, Suzanne; Jane, Jay-Lin; Hollis, James; Li, Li; McClelland, John; Moore, Samuel; Phillips, Gregory J; Rowling, Matthew; Schalinske, Kevin; Scott, M Paul; Whitley, Elizabeth M

    2013-11-01

    Ongoing research to develop digestion-resistant starch for human health promotion integrates the disciplines of starch chemistry, agronomy, analytical chemistry, food science, nutrition, pathology, and microbiology. The objectives of this research include identifying components of starch structure that confer digestion resistance, developing novel plants and starches, and modifying foods to incorporate these starches. Furthermore, recent and ongoing studies address the impact of digestion-resistant starches on the prevention and control of chronic human diseases, including diabetes, colon cancer, and obesity. This review provides a transdisciplinary overview of this field, including a description of types of resistant starches; factors in plants that affect digestion resistance; methods for starch analysis; challenges in developing food products with resistant starches; mammalian intestinal and gut bacterial metabolism; potential effects on gut microbiota; and impacts and mechanisms for the prevention and control of colon cancer, diabetes, and obesity. Although this has been an active area of research and considerable progress has been made, many questions regarding how to best use digestion-resistant starches in human diets for disease prevention must be answered before the full potential of resistant starches can be realized.

  4. A comparative evaluation plan for the Maintenance, Inventory, and Logistics Planning (MILP) System Human-Computer Interface (HCI)

    Science.gov (United States)

    Overmyer, Scott P.

    1993-01-01

    The primary goal of this project was to develop a tailored and effective approach to the design and evaluation of the human-computer interface (HCI) to the Maintenance, Inventory and Logistics Planning (MILP) System in support of the Mission Operations Directorate (MOD). An additional task that was undertaken was to assist in the review of Ground Displays for Space Station Freedom (SSF) by attending the Ground Displays Interface Group (GDIG), and commenting on the preliminary design for these displays. Based upon data gathered over the 10 week period, this project has hypothesized that the proper HCI concept for navigating through maintenance databases for large space vehicles is one based upon a spatial, direct manipulation approach. This dialogue style can be then coupled with a traditional text-based DBMS, after the user has determined the general nature and location of the information needed. This conclusion is in contrast with the currently planned HCI for MILP which uses a traditional form-fill-in dialogue style for all data access and retrieval. In order to resolve this difference in HCI and dialogue styles, it is recommended that comparative evaluation be performed which combines the use of both subjective and objective metrics to determine the optimal (performance-wise) and preferred approach for end users. The proposed plan has been outlined in the previous paragraphs and is available in its entirety in the Technical Report associated with this project. Further, it is suggested that several of the more useful features of the Maintenance Operations Management System (MOMS), especially those developed by the end-users, be incorporated into MILP to save development time and money.

  5. Maintenance management systems

    International Nuclear Information System (INIS)

    Rohan, M. de

    1989-01-01

    This paper is concerned principally with Maintenance Management systems and their effective introduction into organisations. Maintenance improvement is basically a problem of managing the maintenance department in the broadest sense. Improvement does not only lie in the area of special techniques, systems or procedures; although they are valuable tools, but rather in a balanced attack, carefully guided by management. Over recent years, maintenance systems have received the major emphasis and in many instances the selection of the system has become a pre-occupation, whereas the importance of each maintenance function must be recognised and good management practices applied to all maintenance activities. The ingredients for success in the implementation of maintenance management systems are summarised as: having a management committee, clear objectives, project approach using project management techniques and an enthusiastic leader, user managed and data processing supported project, realistic budget and an understanding of the financial audit requirements. (author)

  6. Effectiveness of Cognitive-Behavioral Group Therapy on Improving Quality of Life in Opiate Addicts under Methadone Maintenance Treatment

    Directory of Open Access Journals (Sweden)

    Fereshteh Momeni

    2013-04-01

    Full Text Available Objective: This study was aimed to assess the effectiveness of cognitive- behavioral group therapy on improvement of quality of life in opiate patients under methadone maintenance treatment. Method: This was a semi experimental study using control group also pre-test, post-test and follow-up. Thirty six patients on MMT were selected between the entire opiate addicts referred to Iranian national center for addiction studies within judgmental sampling and were randomly assigned into experimental and control groups. They were all administered the WHOQOL-BREF. In experimental group, cognitive behavior group therapy was performed in 8 sessions and the control group was registered in the waiting list for the CBGT. Findings: Data analysis revealed that the mean WHOQOL-BREF score in the experimental group had significant higher increase when compared with that of the control group. But it wasn’t significant in follow up. Conclusion: Results demonstrated the effectiveness of cognitive–behavior group therapy On improvement of quality of life of opiate addicts on MMT in short term but didn’t seem to be effective in long term.

  7. What's in It for Me? Maintenance of Certification as an Incentive for Faculty Supervision of Resident Quality Improvement Projects.

    Science.gov (United States)

    Rosenbluth, Glenn; Tabas, Jeffrey A; Baron, Robert B

    2016-01-01

    Residents are required to engage in quality improvement (QI) activities, which requires faculty engagement. Because of increasing program requirements and clinical demands, faculty may be resistant to taking on additional teaching and supervisory responsibilities without incentives. The authors sought to create an authentic benefit for University of California, San Francisco (UCSF) Pediatrics Residency Training Program faculty who supervise pediatrics residents' QI projects by offering maintenance of certification (MOC) Part 4 (Performance in Practice) credit. The authors identified MOC as an ideal framework to both more actively engage faculty who were supervising QI projects and provide incentives for doing so. To this end, in 2011, the authors designed an MOC portfolio program which included faculty development, active supervision of residents, and QI projects designed to improve patient care. The UCSF Pediatrics Residency Training Program's Portfolio Sponsor application was approved by the American Board of Pediatrics (ABP) in 2012, and faculty whose projects were included in the application were granted MOC Part 4 credit. As of December 2013, six faculty had received MOC Part 4 credit for their supervision of residents' QI projects. Based largely on the success of this program, UCSF has transitioned to the MOC portfolio program administered through the American Board of Medical Specialties, which allows the organization to offer MOC Part 4 credit from multiple specialty boards including the ABP. This may require refinements to screening, over sight, and reporting structures to ensure the MOC standards are met. Ongoing faculty development will be essential.

  8. Turbine maintenance and modernization

    Energy Technology Data Exchange (ETDEWEB)

    Unga, E. [Teollisuuden Voima Oy, Olkiluoto (Finland)

    1998-12-31

    The disturbance-free operation of the turbine plant plays an important role in reaching good production results. In the turbine maintenance of the Olkiluoto nuclear power plant the lifetime and efficiency of turbine components and the lifetime costs are taken into account in determining the turbine maintenance and modernization/improvement program. The turbine maintenance program and improvement/modernization measures taken in the plant units are described in this presentation. (orig.)

  9. Turbine maintenance and modernization

    Energy Technology Data Exchange (ETDEWEB)

    Unga, E [Teollisuuden Voima Oy, Olkiluoto (Finland)

    1999-12-31

    The disturbance-free operation of the turbine plant plays an important role in reaching good production results. In the turbine maintenance of the Olkiluoto nuclear power plant the lifetime and efficiency of turbine components and the lifetime costs are taken into account in determining the turbine maintenance and modernization/improvement program. The turbine maintenance program and improvement/modernization measures taken in the plant units are described in this presentation. (orig.)

  10. Improving the safety culture of human organizations

    International Nuclear Information System (INIS)

    1990-02-01

    Inquiries into past serious accidents, both nuclear and non-nuclear, reveal that the causes, largely attributed to human error, are also failures on the part of the institutions responsible. Conventional wisdom holds that quality assurance is an essential element for any production process, but the inquiries have not suggested applying quality assurance to the institutions themselves. The ACNS argues the need for Institutional Quality Assurance, with some illustrations of what might be involved, and proposes what should be done to achieve this end

  11. Improved human performance through appropriate work scheduling

    International Nuclear Information System (INIS)

    Morisseau, D.S.; Lewis, P.M.; Persensky, J.J.

    1987-01-01

    The Nuclear Regulatory Commission (NRC) has had a policy, Generic Letter 82-12, on hours of work since 1982. The policy states that licensees should establish controls to prevent situations where fatigue could reduce the ability of operating personnel to perform their duties safely (USNRC 1982). While that policy does give guidance on hours of work and overtime, it does not address periods of longer than 7 days or work schedules other than the routine 8-hour day, 40-hour week. Recognizing that NRC policy could provide broader guidance for shift schedules and hours of overtime work, the Division of Human Factors Safety conducted a project with Pacific Northwest Laboratories (PNL) to help the NRC better understand the human factors principles and issues concerning hours of work so that the NRC could consider updating their policy as necessary. The results of this project are recommendations for guidelines and limits for periods of 14 days, 28 days, and 1 year to take into account the cumulative effects of fatigue. In addition, routine 12-hour shifts are addressed. This latter type of shift schedule has been widely adopted in the petroleum and chemical industries and several utilities operating nuclear power plants have adopted it as well. Since this is the case, it is important to consider including guidelines for implementing this type of schedule. This paper discusses the bases for the PNL recommendations which are currently being studied by the NRC

  12. Human Resource Development's Contribution to Continuous Improvement

    DEFF Research Database (Denmark)

    Jørgensen, Frances; Hyland, Paul

    2007-01-01

    Continuous Improvement (CI) is an approach to organizational change that requires active involvement of skilled and motivated employees, which implies an important role for HRD practitioners. The findings from a literature review and a survey of 168 Danish manufacturing companies indicate however...... that HRD is rarely integrated with CI. The paper contributes by offering a model that depicts how HR and HRD functions could be exploited to support successful CI development and implementation....

  13. Dextromethorphan attenuated inflammation and combined opioid use in humans undergoing methadone maintenance treatment.

    Science.gov (United States)

    Chen, Shiou-Lan; Lee, Sheng-Yu; Tao, Pao-Luh; Chang, Yun-Hsuan; Chen, Shih-Heng; Chu, Chun-Hsien; Chen, Po See; Lee, I Hui; Yeh, Tzung Lieh; Yang, Yen Kuang; Hong, Jau-Shyong; Lu, Ru-Band

    2012-12-01

    Recent studies show that proinflammatory cytokines might be related to the development of opioid dependence (physiological, psychological, or both). In a double-blind, randomly stratified clinical trial investigating whether add-on dextromethorphan (60-120 mg/day) attenuated inflammation and the combined use of opioids in heroin-dependent patients undergoing methadone maintenance treatment, we evaluated whether inflammation is related to the progression of opioid dependence. All participants (107 heroin-dependent patients and 84 nondependent healthy controls) were recruited from National Cheng Kung University Hospital. Their plasma cytokine levels were measured to evaluate the effect of add-on dextromethorphan. Plasma TNF-α and IL-8 levels were significantly higher in long-term heroin-dependent patients than in healthy controls (p dextromethorphan. Moreover, both tolerance to methadone and the combined use of opioids were significantly (p dextromethorphan. We conclude that dextromethorphan might be a feasible adjuvant therapeutic for attenuating inflammation and inhibiting methadone tolerance and combined opioid use in heroin-dependent patients.

  14. A method for accounting for maintenance costs in flux balance analysis improves the prediction of plant cell metabolic phenotypes under stress conditions.

    Science.gov (United States)

    Cheung, C Y Maurice; Williams, Thomas C R; Poolman, Mark G; Fell, David A; Ratcliffe, R George; Sweetlove, Lee J

    2013-09-01

    Flux balance models of metabolism generally utilize synthesis of biomass as the main determinant of intracellular fluxes. However, the biomass constraint alone is not sufficient to predict realistic fluxes in central heterotrophic metabolism of plant cells because of the major demand on the energy budget due to transport costs and cell maintenance. This major limitation can be addressed by incorporating transport steps into the metabolic model and by implementing a procedure that uses Pareto optimality analysis to explore the trade-off between ATP and NADPH production for maintenance. This leads to a method for predicting cell maintenance costs on the basis of the measured flux ratio between the oxidative steps of the oxidative pentose phosphate pathway and glycolysis. We show that accounting for transport and maintenance costs substantially improves the accuracy of fluxes predicted from a flux balance model of heterotrophic Arabidopsis cells in culture, irrespective of the objective function used in the analysis. Moreover, when the new method was applied to cells under control, elevated temperature and hyper-osmotic conditions, only elevated temperature led to a substantial increase in cell maintenance costs. It is concluded that the hyper-osmotic conditions tested did not impose a metabolic stress, in as much as the metabolic network is not forced to devote more resources to cell maintenance. © 2013 The Authors The Plant Journal © 2013 John Wiley & Sons Ltd.

  15. The American Board of Radiology perspective on maintenance of certification: Part IV: Practice quality improvement in radiologic physics

    International Nuclear Information System (INIS)

    Frey, G. Donald; Ibbott, Geoffrey S.; Morin, Richard L.; Paliwal, Bhudatt R.; Thomas, Stephen R.; Bosma, Jennifer

    2007-01-01

    Recent initiatives of the American Board of Medical Specialties (ABMS) in the area of maintenance of certification (MOC) have been reflective of the response of the medical community to address public concerns regarding quality of care, medical error reduction, and patient safety. In March 2000, the 24 member boards of the ABMS representing all medical subspecialties in the USA agreed to initiate specialty-specific maintenance of certification (MOC) programs. The American Board of Radiology (ABR) MOC program for diagnostic radiology, radiation oncology, and radiologic physics has been developed, approved by the ABMS, and initiated with full implementation for all three disciplines beginning in 2007. The overriding objective of MOC is to improve the quality of health care through diplomate-initiated learning and quality improvement. The four component parts to the MOC process are: Part I: Professional standing, Part II: Evidence of life long learning and periodic self-assessment, Part III: Cognitive expertise, and Part IV: Evaluation of performance in practice (with the latter being the focus of this paper). The key components of Part IV require a physicist-based response to demonstrate commitment to practice quality improvement (PQI) and progress in continuing individual competence in practice. Diplomates of radiologic physics must select a project to be completed over the ten-year cycle that potentially can improve the quality of the diplomate's individual or systems practice and enhance the quality of care. Five categories have been created from which an individual radiologic physics diplomate can select one required PQI project: (1) Safety for patients, employees, and the public, (2) accuracy of analyses and calculations, (3) report turnaround time and communication issues, (4) practice guidelines and technical standards, and (5) surveys (including peer review of self-assessment reports). Each diplomate may select a project appropriate for an individual

  16. Importance of Lean Muscle Maintenance to Improve Insulin Resistance by Body Weight Reduction in Female Patients with Obesity

    Directory of Open Access Journals (Sweden)

    Yaeko Fukushima

    2016-03-01

    Full Text Available BackgroundIt has recently been suggested that skeletal muscle has an important role in insulin resistance in obesity, in addition to exercise tolerance and the fat index. The aim of this study was to identify body composition factors that contribute to improvement of insulin resistance in female patients with obesity who reduce body weight.MethodsWe studied 92 female obese patients (age 40.9±10.4 years, body mass index 33.2±4.6 kg/m2 who reduced body weight by ≥5% after an intervention program including diet, exercise therapy, and cognitive behavioral therapy. Before and after the intervention, body composition was evaluated by dual-energy X-ray absorptiometry to examine changes in skeletal muscle mass. Homeostasis model assessment of insulin resistance (HOMA-IR was measured as an index of insulin resistance. Cardiopulmonary exercise was also performed by all patients.ResultsThere were significant improvements in body weight (–10.3%±4.5%, exercise tolerance (anaerobic threshold oxygen uptake 9.1%±18.4%, peak oxygen uptake 11.0%±14.2%, and HOMA-IR (–20.2%±38.3%. Regarding body composition, there were significant decreases in total body fat (–19.3%±9.6%, total fat-free mass (–2.7%±4.3%, and % body fat (–10.1%±7.5%, whereas % skeletal muscle significantly increased (8.9%±7.2%. In stepwise multiple linear regression analysis with change in HOMA-IR as the dependent variable, the change in % skeletal muscle was identified as an independent predictor (β=–0.280, R2=0.068, P<0.01.ConclusionImprovement of insulin resistance in female obese patients requires maintenance of skeletal muscle mass.

  17. Suncor maintenance and reliability

    Energy Technology Data Exchange (ETDEWEB)

    Little, S. [Suncor Energy, Calgary, AB (Canada)

    2006-07-01

    Fleet maintenance and reliability at Suncor Energy was discussed in this presentation, with reference to Suncor Energy's primary and support equipment fleets. This paper also discussed Suncor Energy's maintenance and reliability standard involving people, processes and technology. An organizational maturity chart that graphed organizational learning against organizational performance was illustrated. The presentation also reviewed the maintenance and reliability framework; maintenance reliability model; the process overview of the maintenance and reliability standard; a process flow chart of maintenance strategies and programs; and an asset reliability improvement process flow chart. An example of an improvement initiative was included, with reference to a shovel reliability review; a dipper trip reliability investigation; bucket related failures by type and frequency; root cause analysis of the reliability process; and additional actions taken. Last, the presentation provided a graph of the results of the improvement initiative and presented the key lessons learned. tabs., figs.

  18. Network maintenance

    CERN Multimedia

    GS Department

    2009-01-01

    A site-wide network maintenance operation has been scheduled for Saturday 28 February. Most of the network devices of the general purpose network will be upgraded to a newer software version, in order to improve our network monitoring capabilities. This will result in a series of short (2-5 minutes) random interruptions everywhere on the CERN sites throughout the day. This upgrade will not affect the Computer Centre itself, Building 613, the Technical Network and the LHC experiments, dedicated networks at the pits. For further details of this intervention, please contact Netops by phone 74927 or e-mail mailto:Netops@cern.ch. IT/CS Group

  19. Network maintenance

    CERN Multimedia

    IT Department

    2009-01-01

    A site wide network maintenance has been scheduled for Saturday 28 February. Most of the network devices of the General Purpose network will be upgraded to a newer software version, in order to improve our network monitoring capabilities. This will result in a series of short (2-5 minutes) random interruptions everywhere on the CERN sites along this day. This upgrade will not affect: the Computer centre itself, building 613, the Technical Network and the LHC experiments dedicated networks at the pits. Should you need more details on this intervention, please contact Netops by phone 74927 or email mailto:Netops@cern.ch. IT/CS Group

  20. Neural sources of visual working memory maintenance in human parietal and ventral extrastriate visual cortex.

    Science.gov (United States)

    Becke, Andreas; Müller, Notger; Vellage, Anne; Schoenfeld, Mircea Ariel; Hopf, Jens-Max

    2015-04-15

    Maintaining information in visual working memory is reliably indexed by the contralateral delay activity (CDA) - a sustained modulation of the event-related potential (ERP) with a topographical maximum over posterior scalp regions contralateral to the memorized input. Based on scalp topography, it is hypothesized that the CDA reflects neural activity in the parietal cortex, but the precise cortical origin of underlying electric activity was never determined. Here we combine ERP recordings with magnetoencephalography based source localization to characterize the cortical current sources generating the CDA. Observers performed a cued delayed match to sample task where either the color or the relative position of colored dots had to be maintained in memory. A detailed source-localization analysis of the magnetic activity in the retention interval revealed that the magnetic analog of the CDA (mCDA) is generated by current sources in the parietal cortex. Importantly, we find that the mCDA also receives contribution from current sources in the ventral extrastriate cortex that display a time-course similar to the parietal sources. On the basis of the magnetic responses, forward modeling of ERP data reveals that the ventral sources have non-optimal projections and that these sources are therefore concealed in the ERP by overlapping fields with parietal projections. The present observations indicate that visual working memory maintenance, as indexed by the CDA, involves the parietal cortical regions as well as the ventral extrastriate regions, which code the sensory representation of the memorized content. Copyright © 2015 Elsevier Inc. All rights reserved.

  1. Do humans still forage in an obesogenic environment? Mechanisms and implications for weight maintenance.

    Science.gov (United States)

    Brunstrom, Jeffrey M; Cheon, Bobby K

    2018-02-19

    Many people struggle to control their food intake and bodyweight. This is often interpreted as evidence that humans are generally predisposed to consume food when it is available, because adiposity offered insurance against the threat of starvation in our ancestral environment. In this paper we suggest that modern humans have actually inherited a far broader range of foraging skills that continue to influence our dietary behaviour. To evaluate this idea, we identify three challenges that would need to be addressed to achieve efficient foraging; (1) monitoring the 'procurement cost' of foods, (2) determining the energy content of foods, and (3) proactively adapting to perceived food insecurity. In each case, we review evidence drawn from controlled and observational studies of contemporary humans and conclude that psychological mechanisms that address these challenges are conserved. For contemporary humans who live in fast-paced obesogenic environments, this foraging 'toolkit' no longer serves the same function to which it was adapted, and in many cases, this leads to an increase in food intake. Understanding these forms of 'evolutionary mismatch' is important because it can provide a stronger theoretical basis for informed dietary interventions that leverage fundamental foraging goals rather than work against them. Copyright © 2018. Published by Elsevier Inc.

  2. Preventive maintenance and reliability-centered maintenance

    International Nuclear Information System (INIS)

    Anderson, J.G.

    1989-01-01

    In the recent past, the primary function of the preventive maintenance program at a nuclear power plant was to maintain the operability and reliability of the plant. Reducing overall maintenance costs by performing effective preventive maintenance, instead of more costly and disruptive corrective maintenance, instead of more costly and disruptive corrective maintenance, was a secondary consideration. In today's operating environment, the preventive maintenance program must meet the test of cost-effectiveness as well as many new standards for performance that are being required by rate regulators. The preventive maintenance program must be able to withstand the challenge of independent audit to a new standard of technical adequacy and compliance with recommendations from component vendors. In this new environment, the standard that is being applied at the San Onofre nuclear generating station (SONGS) is that the preventive maintenance program must meet the test of cost-effectiveness, improve equipment performance, support increased plant availability, and (a) literally implement the recommendations of the vendor, (b) provide other compensation for the vendor recommendation, or (c) provide technical justification for the deviation. The subject of this paper is the way that reliability-centered maintenance (RCM) is helping SONGS meet these challenges

  3. The Comparison of Effectiveness of Cognitive-Behavioral Group Therapy Based on Coping Skills and Methadone Maintenance Treatment in Improvement of Emotional Regulation Strategies and Relapse Prevention

    Directory of Open Access Journals (Sweden)

    Tahereh Ghorbany

    2011-05-01

    Full Text Available Purpose: This study compared the effectiveness of group cognitive-behavioral therapy based on coping skills (CBT and methadone maintenance therapy (MMT in improvement of emotional regulation strategies and prevention of relapse. Method: The method of the present study was semi-experimental research design (pre-test-post-test with witness group. For sampling 45 substance abuse people who had referred to addiction treatment centers were selected and assigned to three groups of cognitive behavior therapy, methadone maintenance treatment and witness group randomly. The participants in all three groups completed the emotional intelligence questionnaire before and after the intervention. Data were analyzed by covariance method. Results: The results showed that cognitive-behavior therapy in comparison to methadone maintenance therapy and witness group led to significant improvement of emotional regulation in substance abusers, but there was no significant difference between the methadone maintenance treatment group and control group. Also, the rate of relapse in individuals who assigned to cognitive-behavior therapy group in comparison to methadone maintenance therapy and the witness group was significantly lower, but there was no significant difference between methadone therapy and witness. Conclusion: Cognitive-behavior therapy was an effective treatment that can change the cognitive and behavioral variables related to substance abuse, such as emotional regulation strategies. Thus, results suggested that drug abuse treatment programs must target these mediator variables.

  4. Defining differentially methylated regions specific for the acquisition of pluripotency and maintenance in human pluripotent stem cells via microarray.

    Directory of Open Access Journals (Sweden)

    WenYin He

    Full Text Available Epigenetic regulation is critical for the maintenance of human pluripotent stem cells. It has been shown that pluripotent stem cells, such as embryonic stem cells and induced pluripotent stem cells, appear to have a hypermethylated status compared with differentiated cells. However, the epigenetic differences in genes that maintain stemness and regulate reprogramming between embryonic stem cells and induced pluripotent stem cells remain unclear. Additionally, differential methylation patterns of induced pluripotent stem cells generated using diverse methods require further study.Here, we determined the DNA methylation profiles of 10 human cell lines, including 2 ESC lines, 4 virally derived iPSC lines, 2 episomally derived iPSC lines, and the 2 parental cell lines from which the iPSCs were derived using Illumina's Infinium HumanMethylation450 BeadChip. The iPSCs exhibited a hypermethylation status similar to that of ESCs but with distinct differences from the parental cells. Genes with a common methylation pattern between iPSCs and ESCs were classified as critical factors for stemness, whereas differences between iPSCs and ESCs suggested that iPSCs partly retained the parental characteristics and gained de novo methylation aberrances during cellular reprogramming. No significant differences were identified between virally and episomally derived iPSCs. This study determined in detail the de novo differential methylation signatures of particular stem cell lines.This study describes the DNA methylation profiles of human iPSCs generated using both viral and episomal methods, the corresponding somatic cells, and hESCs. Series of ss-DMRs and ES-iPS-DMRs were defined with high resolution. Knowledge of this type of epigenetic information could be used as a signature for stemness and self-renewal and provides a potential method for selecting optimal pluripotent stem cells for human regenerative medicine.

  5. Human Pro-Social Motivation and the Maintenance of Social Order

    OpenAIRE

    Gaechter, Simon

    2014-01-01

    This chapter presents some insights from basic behavioural research on the role of human pro-social motivation to maintain social order. I argue that social order can be conceptualized as a public good game. Past attempts to explain social order typically relied on the assumption of selfish and rational agents ("homo economicus"). The last twenty years of research in behavioural and experimental economics have challenged this view. After presenting the most important findings of recent resear...

  6. Improving the Status of Human and Material Resources in Public ...

    African Journals Online (AJOL)

    Improving the Status of Human and Material Resources in Public Primary School in Oyo States ... the Millennium Development Goals project in the State. ... libraries, well-equipped first aid centres, adequate electronically projected instructional ...

  7. [Acupuncture therapy for the improvement of sleep quality of outpatients receiving methadone maintenance treatment: a randomized controlled trial].

    Science.gov (United States)

    Li, Yi; Liu, Xue-bing; Zhang, Yao

    2012-08-01

    To study the efficacy and safety of acupuncture therapy for the improvement of sleep quality of outpatients receiving methadone maintenance treatment (MMT). Using randomized double-blinded controlled design, seventy-five MMT outpatients with low sleep quality [score of Pittsburgh sleep quality index (PSQI) > or = 8], were randomly assigned to the acupuncture group (38 cases) and the sham-acupuncture group (37 cases). All patients maintained previous MMT. Acupuncture was applied to Baihui (GV20), Shenmen (bilateral, TF4), Shenting (GV24), Sanyinjiao (bilateral, SP6), and Sishencong (EX-HN1) in the acupuncture group. The same procedures were performed in the sham-acupuncture group, but not to the acupoints (5 mm lateral to the acupoints selected in the acupuncture group) with shallow needling technique. The treatment was performed 5 times each week for 8 successive weeks. The PSQI was assessed before treatment, at the end of the 2nd, 4th, 6th, and 8th week of the treatment. The detection ratio of low sleep quality and the incidence of adverse acupuncture reactions were compared between the two groups at the end of the 8th week. The overall PSQI score was obviously higher in the acupuncture group than in the sham-acupuncture group with statistical difference (P acupuncture group (60.53%, 23/38 cases) than in the sham-acupuncture group (83.78%, 31/37 cases) with statistical difference (P acupuncture reaction was 5.26% (2/38 cases) in the acupuncture group and 2.70% (1/37 cases) in the sham-acupuncture group respectively, showing no statistical difference (P > 0.05). Acupuncture therapy could effectively and safely improve the sleep quality of outpatients receiving MMT.

  8. Ecological Interface Design of Augmented Reality Display for Nuclear Power Plant Maintenance

    International Nuclear Information System (INIS)

    Kim, In; Seong, Poong Hyun

    2008-01-01

    The importance of maintenance in nuclear power plants (NPPs) has been emphasized through many researches. The goals of maintenance in nuclear power plants are not only to reduce the number of shutdowns which directly affects to the profit, but also to prevent accidents or incidents hence improves nuclear safety. It is known that reduction of the rate of human error in maintenance tasks can be achieved if maintenance personnel are properly supported by maintenance support systems. Among many proposed maintenance support system, the use of augmented reality (AR) has been proposed

  9. A feeder-free, human plasma-derived hydrogel for maintenance of a human embryonic stem cell phenotype in vitro

    Directory of Open Access Journals (Sweden)

    Lewis Fiona C

    2012-08-01

    Full Text Available Abstract Background Human embryonic stem cells (hESCs represent a tremendous resource for cell therapies and the study of human development; however to maintain their undifferentiated state in vitro they routinely require the use of mouse embryonic fibroblast (MEF feeder-layers and exogenous protein media supplementation. Results These well established requirements can be overcome and in this study, it will be demonstrated that phenotypic stability of hESCs can be maintained using a novel, human plasma protein-based hydrogel as an extracellular culture matrix without the use of feeder cell co-culture. hESCs were resuspended in human platelet poor plasma (PPP, which was gelled by the addition of calcium containing DMEM-based hESC culture medium. Phenotypic and genomic expression of the pluripotency markers OCT4, NANOG and SOX2 were measured using immunohistochemistry and qRT-PCR respectively. Typical hESC morphology was demonstrated throughout in vitro culture and both viability and phenotypic stability were maintained throughout extended culture, up to 25 passages. Conclusions PPP-derived hydrogel has demonstrated to be an efficacious alternative to MEF co-culture with its hydrophilicity allowing for this substrate to be delivered via minimally invasive procedures in a liquid phase with polymerization ensuing in situ. Together this provides a novel technique for the study of this unique group of stem cells in either 2D or 3D both in vitro and in vivo.

  10. Sequence of interleukin-2 isolated from human placental poly A+ RNA: possible role in maintenance of fetal allograft.

    Science.gov (United States)

    Chernicky, C L; Tan, H; Burfeind, P; Ilan, J; Ilan, J

    1996-02-01

    There are several cell types within the placenta that produce cytokines which can contribute to the regulatory mechanisms that ensure normal pregnancy. The immunological milieu at the maternofetal interface is considered to be crucial for survival of the fetus. Interleukin-2 (IL-2) is expressed by the syncytiotrophoblast, the cell layer between the mother and the fetus. IL-2 appears to be a key factor in maintenance of pregnancy. Therefore, it was important to determine the sequence of human placental interleukin-2. Direct sequencing of human placental IL-2 cDNA was determined for the coding region. Subclone sequencing was carried out for the 5'- and 3'-untranslated regions (5'-UTR and 3'-UTR). The 5'-UTR for human placental IL-2 cDNA is 294 bp, which is 247 nucleotides longer than that reported for cDNA IL-2 derived from T cells. The sequence of the coding region is identical to that reported for T cell IL-2, while sequence analysis of the polymerase chain reaction (PCR) product showed that the cDNA from the 3' end was the same as that reported for cDNA from T cells. Human placental IL-2 cDNA is 1,028 base pairs (excluding the poly A tail), which is 247 bp longer at the 5' end than that reported for IL-2 T cell cDNA. Therefore, the extended 5'-UTR of the placental IL-2 cDNA may be a consequence of alternative promoter utilization in the placenta.

  11. Strategies for Improving Maintenance and Generalization of Academic Skills--So Students "Don't Leave Class without It."

    Science.gov (United States)

    Gable, Robert A.; And Others

    1992-01-01

    An instructional process for facilitating maintenance and generalization of academic skills is presented, using the ABCD'S (Antecedent Events, Behavior, Consequent Events, Data, and Setting Events) Generalization Intervention Model. (JDD)

  12. Human Factors in Aviation Maintenance. Phase 3. Volume 2. Progress Report

    Science.gov (United States)

    1994-07-01

    race-role identities are usually attributed to one of three factors: innate biological differences, cognitive-developmental parameters, or social...Improve facilities to be more gender fair 111 Chapter Four 4.7 REFERENCES Aburdene, P., & Naisbitt, J. (1992). Megatrends for women. New York... biological basis of personality. Springfield, Illinois: Thomas. Eysenck, S. B. G. & Eysenck, H. J. (1963). On the dual nature of extraversion. British

  13. Study on human-factors-engineering properties of reactor maintenance workers with protection suits, (2). Basic research on various biological characteristics in reactor maintenance simulation tests

    Energy Technology Data Exchange (ETDEWEB)

    Yoshino, K; Ishii, K; Nakasa, H [Central Research Inst. of Electric Power Industry, Tokyo (Japan); Shigeta, S

    1980-11-01

    To ensure the safety of reactor maintenance workers and to reduce the radiation exposure through the enhancement of labor efficiency, it is needed to evaluate quantitatively work-stress levels of workers with radiation-protection suits. This paper presents the results of reactor-maintenance simulation tests in which the relationship between the work stress and biological characteristics is investigated for 5 pinds of model works done by testees without protection suits in an artificial climate chamber. Major results obtained are: (1) the selected model works are mostly evaluated to be relatively heavy through the measurement of RMR (Relative Metabolic Rate). (2) biological characteristics such as heart rate and respiratory volume under the model works have close relationship to RMR which is the cumulative quantity in relatively long time, and then they may become the real-time indicator for the work stress level. (3) such biological characteristics are greatly affected by the high-temperature work-environment which is often seen in workers with protection suits.

  14. Providing Our Fellows in Training with Education on Inflammatory Bowel Disease Health Maintenance to Improve the Quality of Care in Our Health Care System.

    Science.gov (United States)

    Lee, Ann Joo; Kraemer, Dale F; Smotherman, Carmen; Eid, Emely

    2016-01-01

    Inflammatory bowel disease (IBD) quality measures were established in an effort to standardize IBD health care. Despite effort to improve clinical performance, considerable variations in practice still exist. To further improve IBD health care, we propose incorporating an in-service educational session on IBD health maintenance to provide trainees with increasing awareness and knowledge on IBD management. Fifty electronic medical charts were randomly selected, and the level of quality documentation was assessed for 15 core IBD quality measures. Data were reported as the percentage of charts meeting audit criteria (compliance score). Fellows then attended an in-service educational session to review IBD quality measures and reinforce practice expectations. A second audit was then performed on an additional 50 patient charts to determine whether documentation practices improved after the educational session. We found a positive correlation between an in-service educational session and fellows' compliance with IBD health maintenance. Overall, the fellows' compliance score increased by 18% (before intervention, 65%; after intervention, 83%; P bases for IBD health maintenance. Incorporating a standard curriculum on IBD health maintenance provides fellows in training with increased awareness and guidance on managing the unique preventive care needs of patients with IBD.

  15. The improving processes in the human resources management

    OpenAIRE

    Darja Holátová

    2002-01-01

    The quality management of the human resources management, the quality of the products, services and prosperities of the firms is among others dependent on the quality management. Managers convey a leadership and commitment necessary for creating the environment for quality improvement. The managers are responsible for their own actions, development and improvement of their own work processes.

  16. Management of remanent lifetime. Short-term benefits of the maintenance evaluation and improvement programme; Gestion de la vida remanente de instalaciones industriales. Extension de vida

    Energy Technology Data Exchange (ETDEWEB)

    Sainero Garcia, J [Empresarios Agrupados, Madrid (Spain)

    1993-12-15

    Remanent Lifetime Management, which is scientifically based on knowing the degradatory phenomena associated with aging, today allows us to optimize plant life through a long-term maintenance strategy combining preventive maintenance and condition monitoring programmes. Within a project for Remanent Lifetime Management (RLM), the determination of methods of control and mitigation of degradations due to aging depends on the programme of Maintenance Evaluation and Improvement (MEI). This programme, underpinned by the analysis of degradatory phenomena to which plant components are subjected, evaluates current maintenance practices and defines the complementary actions which would facilitate establishment of a long-term strategy to control aging. Together with this main objective of the RLM project, the MEI programme achieves short-term benefits since, right from the beginning, it offers solutions to mitigate and guard against degradations in crucial plant components, and generally sets out a programme to control aging. The MEI programme further serves as a tool to reach the final objectives of the new 10CFR50.65 rule, 'Requirements for Maintenance Programs for NPPs'. The MEI always offers the option should the Utility Owner decide to extend plant life. (author)

  17. Converging Technologies for Improving Human Performance: Integrating From the Nanoscale

    International Nuclear Information System (INIS)

    Roco, M.C.; Bainbridge, W.S.

    2002-01-01

    In the early decades of the twenty-first century, concentrated efforts can unify science based on the unity of nature, thereby advancing the combination of nanotechnology, biotechnology, information technology, and new humane technologies based in cognitive science. Converging technologies integrated from the nanoscale could determine a tremendous improvement in human abilities and societal outcomes. This is a broad, cross cutting, emerging, and timely opportunity of interest to individuals, society, and humanity in the long term.About eighty scientific leaders, industry experts, and policy makers across a range of fields have contributed to develop a vision for the potential to improve human physical, mental, and social capabilities through the convergence of the four technologies. Six major themes have emerged: (a) The broad potential of converging technologies; (b) Expanding human cognition and communication; (c) Improving human health and physical capabilities; (d) Enhancing group and societal outcomes; (e) National security, and (f) Unifying science and education. This article summarizes the observations, conclusions, and recommendations made in the report (Roco and Bainbridge, eds., 2002. Converging Technologies for Improving Human Performance, NSF-DOC Report, June 2002, Arlington VA, USA)

  18. Human Capacity Building in Energy Efficiency and Renewable Energy System Maintenance for the Yurok Tribe

    Energy Technology Data Exchange (ETDEWEB)

    Engel, R. A.' Zoellick, J J.

    2007-07-31

    From July 2005 to July 2007, the Schatz Energy Research Center (SERC) assisted the Yurok Tribe in the implementation of a program designed to build the Tribe’s own capacity to improve energy efficiency and maintain and repair renewable energy systems in Tribal homes on the Yurok Reservation. Funding for this effort was provided by the U.S. Department of Energy’s Tribal Program under First Steps grant award #DE-FG36-05GO15166. The program’s centerpiece was a house-by-house needs assessment, in which Tribal staff visited and conducted energy audits at over fifty homes. The visits included assessment of household energy efficiency and condition of existing renewable energy systems. Staff also provided energy education to residents, evaluated potential sites for new household renewable energy systems, and performed minor repairs as needed on renewable energy systems.

  19. Information Management System Development for the Investigation, Reporting, and Analysis of Human Error in Naval Aviation Maintenance

    National Research Council Canada - National Science Library

    Nelson, Douglas

    2001-01-01

    The purpose of this research is to evaluate and refine a safety information management system that will facilitate data collection, organization, query, analysis and reporting of maintenance errors...

  20. An experimental maintenance management system.

    Science.gov (United States)

    1979-01-01

    The purpose of this study was to evaluate Virginia's maintenance management system and to recommend modifications directed at improving it. The study revealed that (1) the current system of allocating maintenance monies is based upon centerline milea...

  1. Improved inflammatory activity with peginterferon alfa-2b maintenance therapy in non-cirrhotic prior non-responders: a randomized study.

    Science.gov (United States)

    Poynard, Thierry; Bruix, Jordi; Schiff, Eugene R; Diago, Moises; Berg, Thomas; Moreno-Otero, Ricardo; Lyra, Andre C; Carrilho, Flair; Griffel, Louis H; Boparai, Navdeep; Jiang, Ruiyun; Burroughs, Margaret; Brass, Clifford A; Albrecht, Janice K

    2013-03-01

    Therapeutic options for patients failing hepatitis C retreatment are limited. EPIC(3) included a prospective trial assessing long-term peginterferon alfa-2b (PegIFNα-2b) maintenance therapy in patients with METAVIR fibrosis scores (MFS) of F2 or F3 who previously failed hepatitis C retreatment. Patients with F2/F3 MFS who failed retreatment were randomized to PegIFNα-2b (0.5 μg/kg/week, n=270) or observation (n=270) for 36 months. Blinded liver biopsies obtained before retreatment and after maintenance therapy were evaluated using MFS and activity scores, and confirmatory testing was performed using FibroTest and ActiTest. In total, 348 patients had paired biopsies: 192 patients had missing post-treatment biopsies and were considered as having no change in fibrosis/activity scores. In total, 16% of patients receiving PegIFNα-2b and 11% of observation patients had improvement in MFS (p=0.32). More PegIFNα-2b than observation patients had improvement in activity score (20% vs. 9%; p 2.5 years, improvement in MFS or activity score was more common with PegIFNα-2b than observation (21% vs. 14%, p=0.08 and 26% vs. 10%, p 2.5 years. Both FibroTest and ActiTest were significantly improved during maintenance therapy. Copyright © 2012 European Association for the Study of the Liver. Published by Elsevier B.V. All rights reserved.

  2. Expansion and maintenance of human embryonic stem cell–derived endothelial cells by TGFβ inhibition is Id1 dependent

    Science.gov (United States)

    James, Daylon; Nam, Hyung-song; Seandel, Marco; Nolan, Daniel; Janovitz, Tyler; Tomishima, Mark; Studer, Lorenz; Lee, Gabsang; Lyden, David; Benezra, Robert; Zaninovic, Nikica; Rosenwaks, Zev; Rabbany, Sina Y; Rafii, Shahin

    2010-01-01

    Previous efforts to differentiate human embryonic stem cells (hESCs) into endothelial cells have not achieved sustained expansion and stability of vascular cells. To define vasculogenic developmental pathways and enhance differentiation, we used an endothelial cell–specific VE-cadherin promoter driving green fluorescent protein (GFP) (hVPr-GFP) to screen for factors that promote vascular commitment. In phase 1 of our method, inhibition of transforming growth factor (TGF)β at day 7 of differentiation increases hVPr-GFP+ cells by tenfold. In phase 2, TGFβ inhibition maintains the proliferation and vascular identity of purified endothelial cells, resulting in a net 36-fold expansion of endothelial cells in homogenous monolayers, which exhibited a transcriptional profile of Id1highVEGFR2highVE-cadherin+ ephrinB2+. Using an Id1-YFP hESC reporter line, we showed that TGFβ inhibition sustains Id1 expression in hESC-derived endothelial cells and that Id1 is required for increased proliferation and preservation of endothelial cell commitment. Our approach provides a serum-free method for differentiation and long-term maintenance of hESC-derived endothelial cells at a scale relevant to clinical application. PMID:20081865

  3. Improving human performance: Industry factors influencing the ability to perform

    OpenAIRE

    Güera Massyn Romo

    2013-01-01

    Learning interventions and new technologies that aim to improve human performance must take cognisance of industry factors inhibiting human performance. The dynamic and fast pace nature of the Information and Communication Technologies (ICT) and the engineering industries do not lend themselves to proper skills planning and management. These industries experience real skills gaps, to some of which they contribute by themselves. This study reports on these performance-inhibiting factors such a...

  4. National plan to enhance aviation safety through human factors improvements

    Science.gov (United States)

    Foushee, Clay

    1990-01-01

    The purpose of this section of the plan is to establish a development and implementation strategy plan for improving safety and efficiency in the Air Traffic Control (ATC) system. These improvements will be achieved through the proper applications of human factors considerations to the present and future systems. The program will have four basic goals: (1) prepare for the future system through proper hiring and training; (2) develop a controller work station team concept (managing human errors); (3) understand and address the human factors implications of negative system results; and (4) define the proper division of responsibilities and interactions between the human and the machine in ATC systems. This plan addresses six program elements which together address the overall purpose. The six program elements are: (1) determine principles of human-centered automation that will enhance aviation safety and the efficiency of the air traffic controller; (2) provide new and/or enhanced methods and techniques to measure, assess, and improve human performance in the ATC environment; (3) determine system needs and methods for information transfer between and within controller teams and between controller teams and the cockpit; (4) determine how new controller work station technology can optimally be applied and integrated to enhance safety and efficiency; (5) assess training needs and develop improved techniques and strategies for selection, training, and evaluation of controllers; and (6) develop standards, methods, and procedures for the certification and validation of human engineering in the design, testing, and implementation of any hardware or software system element which affects information flow to or from the human.

  5. Terroir as a Concept to Improve Human Health

    Science.gov (United States)

    Brevik, Eric C.; Steffan, Joshua J.; Burgess, Lynn C.; Cerdà, Artemi; Pereg, Lily

    2017-04-01

    Soil is important to human health because of the ability of healthy soils to supply nutrients through food products, medications derived from soil, its ability to clean water, and for many other positive reasons. On the other hand, degraded soils can have negative impacts on human health through processes such as dust generation and by acting as a point of human contact with heavy metals, organic chemicals, and pathogens. Despite the definite links between soil and human health, it is likely that most people don't think about soil when considering human health issues. In fact, there appears to be a disconnect between most people in our modern society and soil, and when people do notice soil it often seems to be in a negative context, leading to terms such as "soiled", "dirty", "dirt poor", etc. People pay attention to and care for things that matter to them, and creating a more positive public image of soil has the possibility of improving human health by leading to careful and caring treatment of the soil resource. The concept of terroir is a good example of a setting within which soils have a more positive image. While terroir originally established a connection between those who love wine and the soils that produce those wines, the concept has been expanded to many additional products such as cacao, cheese, coffee, fruits, olive oil, and vegetables. If the terroir concept could be expanded to include additional products that are important to people and expanded into parts of the world where it is not currently well known, that may provide an increased positive perception of soil, and thereby indirectly improve human health. It may even be possible to provide a terroir link to direct health benefits, such as medications derived from a given soil environment, and therefore provide a very focused emphasis on soil and human health issues. Therefore, we advocate a concerted effort to expand the terroir concept as a means to improve overall human health.

  6. Managing Human Performance to Improve Nuclear Facility Operation

    International Nuclear Information System (INIS)

    2013-01-01

    One of the IAEA's statutory objectives is to 'seek to accelerate and enlarge the contribution of atomic energy to peace, health and prosperity throughout the world.' One way this objective is achieved is through the publication of a range of technical series. Two of these are the IAEA Nuclear Energy Series and the IAEA Safety Standards Series. According to Article III.A.6 of the IAEA Statute, the safety standards establish 'standards of safety for protection of health and minimization of danger to life and property'. The safety standards include the Safety Fundamentals, Safety Requirements and Safety Guides. These standards are written primarily in a regulatory style, and are binding on the IAEA for its own programmes. The principal users are the regulatory bodies in Member States and other national authorities. The IAEA Nuclear Energy Series comprises reports designed to encourage and assist R and D on, and application of, nuclear energy for peaceful uses. This includes practical examples to be used by owners and operators of utilities in Member States, implementing organizations, academia, and government officials, among others. This information is presented in guides, reports on technology status and advances, and best practices for peaceful uses of nuclear energy based on inputs from international experts. The IAEA Nuclear Energy Series complements the IAEA Safety Standards Series. IAEA Nuclear Energy Series No. NG-G-2.1, Managing Human Resources in the Field of Nuclear Energy, was published in 2009. In that publication, four interrelated objectives of the management of human resources were identified and discussed: ensuring that nuclear industry personnel have the necessary competence for their jobs; effectively organizing work activities; anticipating human resource needs; and monitoring and continually improving performance. This publication addresses the fourth objective and, in particular, summarizes good practices in the area of managing human performance

  7. NOTCH-Mediated Maintenance and Expansion of Human Bone Marrow Stromal/Stem Cells: A Technology Designed for Orthopedic Regenerative Medicine.

    Science.gov (United States)

    Dong, Yufeng; Long, Teng; Wang, Cuicui; Mirando, Anthony J; Chen, Jianquan; O'Keefe, Regis J; Hilton, Matthew J

    2014-12-01

    Human bone marrow-derived stromal/stem cells (BMSCs) have great therapeutic potential for treating skeletal disease and facilitating skeletal repair, although maintaining their multipotency and expanding these cells ex vivo have proven difficult. Because most stem cell-based applications to skeletal regeneration and repair in the clinic would require large numbers of functional BMSCs, recent research has focused on methods for the appropriate selection, expansion, and maintenance of BMSC populations during long-term culture. We describe here a novel biological method that entails selection of human BMSCs based on NOTCH2 expression and activation of the NOTCH signaling pathway in cultured BMSCs via a tissue culture plate coated with recombinant human JAGGED1 (JAG1) ligand. We demonstrate that transient JAG1-mediated NOTCH signaling promotes human BMSC maintenance and expansion while increasing their skeletogenic differentiation capacity, both ex vivo and in vivo. This study is the first of its kind to describe a NOTCH-mediated methodology for the maintenance and expansion of human BMSCs and will serve as a platform for future clinical or translational studies aimed at skeletal regeneration and repair. ©AlphaMed Press.

  8. A modified HPLC method improves the simultaneous determination of plasma kynurenine and tryptophan concentrations in patients following maintenance hemodialysis

    Science.gov (United States)

    XIAO, CHENGGEN; CHEN, YUANHAN; LIANG, XINLING; XIE, ZHEN; ZHANG, MIN; LI, RUIZHAO; LI, ZHILIAN; FU, XIA; YU, XIYONG; SHI, WEI

    2014-01-01

    The ratio between plasma kynurenine (Kyn) and tryptophan (Trp) serves as a marker of indoleamine 2,3-dioxygenase, a critical immunomodulatory molecule. Simultaneous detection of the two markers may be performed using high-pressure liquid chromatography (HPLC). However, for uremic patients, the conventional detection method may be affected by a range of accumulated toxins. The current study aimed to establish a method for the simultaneous measurement of Kyn and Trp in patients following maintenance hemodialysis via HPLC-ultraviolet detection. The procedure involved the use of a SinoChrom ODS-BP C18 column (4.6×150 mm; inner diameter, 4.5 μm) and a mobile phase of 15 mmol/l sodium acetate acetic acid solution (containing 5% acetonitrile, pH 4.8). The modified method was verified using plasma samples from 10 healthy controls and 91 maintenance hemodialysis patients. The results demonstrated that the modified method was successful in simultaneously detecting the concentrations of Trp and Kyn in the healthy controls and maintenance hemodialysis patients. The method is simple, fast, accurate and suitable for clinical and research purposes in maintenance hemodialysis patients. PMID:24669249

  9. International Atomic Energy Agency specialists meeting on experience in ageing, maintenance, and modernization of instrumentation and control systems for improving nuclear power plant availability

    International Nuclear Information System (INIS)

    1993-10-01

    This report presents the proceedings of the Specialist's Meeting on Experience in Aging, Maintenance and Modernization of Instrumentation and Control Systems for Improving Nuclear Power Plant Availability that was held at the Ramada Inn in Rockville, Maryland on May 5--7, 1993. The Meeting was presented in cooperation with the Electric Power Research Institute, Oak Ridge National Laboratory and the International Atomic Energy Agency. There were approximately 65 participants from 13 countries at the Meeting. Individual reports have been cataloged separately

  10. Technologies for improving current and future light water reactor operation and maintenance: Development on the basis of experience. Proceedings of a technical committee meeting

    International Nuclear Information System (INIS)

    2000-09-01

    Application of efficient technologies for improving operation and maintenance of nuclear power plants is an important element for assuring their economic competitiveness with other means of generating electricity. The competitive environment, which nuclear power plant operators face in many countries as a result of de-regulation of the electricity market, imposes cost pressures that must be met while at the same time satisfying stringent safety requirements. Further, as currently operating plants age, proper management includes development and application of better technologies for inspection, maintenance and repair. For future plants, the opportunity exists during the design phase to incorporate design features for performing efficient inspection, maintenance and repairs. Despite the prevailing low prices of fossil fuels, the generation costs of nuclear electricity continue to be competitive with electricity generation costs from fossil-fuelled plants for base load generation in several countries. For nuclear power, the capital investment component of electricity generation cost is relatively high, while the nuclear fuel cycle cost is - and is expected to remain - relatively low. The prices of fossil fuels are fairly low today but are likely to increase over the long term because the resource is limited. Moreover, governments may introduce incentives to reduce the use of fossil fuels in order to protect the environment. In many countries, nuclear utilities are experiencing increased competition with other sources of electricity production due to deregulation of the electricity market, and nuclear plant operators can no longer pass along the generation costs to consumers through regulated electricity rates. This competitive environment has significant implications for plant operations to achieve efficient use of all resources, and to effectively manage plant activities including outages and maintenance. Over the past several years, steady improvements have been

  11. Technologies for improving current and future light water reactor operation and maintenance: Development on the basis of experience. Proceedings of a technical committee meeting

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2000-09-01

    Application of efficient technologies for improving operation and maintenance of nuclear power plants is an important element for assuring their economic competitiveness with other means of generating electricity. The competitive environment, which nuclear power plant operators face in many countries as a result of de-regulation of the electricity market, imposes cost pressures that must be met while at the same time satisfying stringent safety requirements. Further, as currently operating plants age, proper management includes development and application of better technologies for inspection, maintenance and repair. For future plants, the opportunity exists during the design phase to incorporate design features for performing efficient inspection, maintenance and repairs. Despite the prevailing low prices of fossil fuels, the generation costs of nuclear electricity continue to be competitive with electricity generation costs from fossil-fuelled plants for base load generation in several countries. For nuclear power, the capital investment component of electricity generation cost is relatively high, while the nuclear fuel cycle cost is - and is expected to remain - relatively low. The prices of fossil fuels are fairly low today but are likely to increase over the long term because the resource is limited. Moreover, governments may introduce incentives to reduce the use of fossil fuels in order to protect the environment. In many countries, nuclear utilities are experiencing increased competition with other sources of electricity production due to deregulation of the electricity market, and nuclear plant operators can no longer pass along the generation costs to consumers through regulated electricity rates. This competitive environment has significant implications for plant operations to achieve efficient use of all resources, and to effectively manage plant activities including outages and maintenance. Over the past several years, steady improvements have been

  12. Improved Human Erythropoiesis and Platelet Formation in Humanized NSGW41 Mice

    Directory of Open Access Journals (Sweden)

    Susann Rahmig

    2016-10-01

    Full Text Available Human erythro-megakaryopoiesis does not occur in humanized mouse models, preventing the in vivo analysis of human hematopoietic stem cell (HSC differentiation into these lineages in a surrogate host. Here we show that stably engrafted KIT-deficient NOD/SCID Il2rg−/− KitW41/W41 (NSGW41 mice support much improved human erythropoiesis and platelet formation compared with irradiated NSG recipients. Considerable numbers of human erythroblasts and mature thrombocytes are present in the bone marrow and blood, respectively. Morphology, composition, and enucleation capacity of de novo generated human erythroblasts in NSGW41 mice are comparable with those in human bone marrow. Overexpression of human erythropoietin showed no further improvement in human erythrocyte output, but depletion of macrophages led to the appearance of human erythrocytes in the blood. Human erythropoiesis up to normoblasts and platelet formation is fully supported in NSGW41 mice, allowing the analysis of human HSC differentiation into these lineages, the exploration of certain pathophysiologies, and the evaluation of gene therapeutic approaches.

  13. Warning Signals for Poor Performance Improve Human-Robot Interaction

    NARCIS (Netherlands)

    van den Brule, Rik; Bijlstra, Gijsbert; Dotsch, Ron; Haselager, Pim; Wigboldus, Daniel HJ

    2016-01-01

    The present research was aimed at investigating whether human-robot interaction (HRI) can be improved by a robot’s nonverbal warning signals. Ideally, when a robot signals that it cannot guarantee good performance, people could take preventive actions to ensure the successful completion of the

  14. Promoting Instructional Improvement: A Strategic Human Resource Management Perspective

    Science.gov (United States)

    Smylie, Mark A.; Wenzel, Stacy A.

    2006-01-01

    This report argues that instructional improvement, which goes hand-in-hand with efforts at education reform, can be promoted through the strategic use of human resource management (HRM) practices at the school, district, and state levels. The authors present information from the organizational and management literatures on how firms in several…

  15. Driving Performance Improvements by Integrating Competencies with Human Resource Practices

    Science.gov (United States)

    Lee, Jin Gu; Park, Yongho; Yang, Gi Hun

    2010-01-01

    This study explores the issues in the development and application of a competency model and provides implications for more precise integration of competencies into human resource (HR) functions driving performance improvement. This research is based on a case study from a Korean consumer corporation. This study employed document reviews,…

  16. Improving of the management quality of human resources

    OpenAIRE

    Miceski, Trajko

    2004-01-01

    Improvement of the management quality of human resources is a continuous process, based on multidimensional concept of activities, with special emphasis on increasing the level of competence of the employees both in their working place and in additional activities in the decision making bodies.

  17. Advances in safety related maintenance

    International Nuclear Information System (INIS)

    2000-03-01

    The maintenance of systems, structures and components in nuclear power plants (NPPs) plays an important role in assuring their safe and reliable operation. Worldwide, NPP maintenance managers are seeking to reduce overall maintenance costs while maintaining or improving the levels of safety and reliability. Thus, the issue of NPP maintenance is one of the most challenging aspects of nuclear power generation. There is a direct relation between safety and maintenance. While maintenance alone (apart from modifications) will not make a plant safer than its original design, deficient maintenance may result in either an increased number of transients and challenges to safety systems or reduced reliability and availability of safety systems. The confidence that NPP structures, systems and components will function as designed is ultimately based on programmes which monitor both their reliability and availability to perform their intended safety function. Because of this, approaches to monitor the effectiveness of maintenance are also necessary. An effective maintenance programme ensures that there is a balance between the improvement in component reliability to be achieved and the loss of component function due to maintenance downtime. This implies that the safety level of an NPP should not be adversely affected by maintenance performed during operation. The nuclear industry widely acknowledges the importance of maintenance in NPP safety and operation and therefore devotes great efforts to develop techniques, methods and tools to aid in maintenance planning, follow-up and optimization, and in assuring the effectiveness of maintenance

  18. Improved extraction procedure for carotenoids from human milk.

    Science.gov (United States)

    Schweigert, F J; Hurtienne, A; Bathe, K

    2000-05-01

    An improved method for the extraction of the major carotenoids from human milk is described. Carotenoids were extracted from milk first with ethanol and n-hexane. Then, polar xanthophylls were extracted from n-hexane into ethanol/water. The remaining n-hexane was evaporated, the residue combined with the ethanolic milk fraction and the mixture briefly saponified. Carotenoids were extracted from the hydrolysate with n-hexane, combined with the polar xanthophylls from the non-saponified ethanol/water-extract and separated by HPLC. Using this method we were able to significantly improve the recovery of xanthophylls such as lutein and zeaxanthin from human milk. The recovery rate of all carotenoids was > 90%. This method might not only be of value for milk but should be especially useful in the extraction of carotenoids from human tissues such as the adipose tissue.

  19. System ergonomics as an approach to improve human reliability

    International Nuclear Information System (INIS)

    Bubb, H.

    1988-01-01

    The application of system technics on ergonomical problems is called system ergonomics. This enables improvements of human reliability by design measures. The precondition for this is the knowledge of how information processing is performed by man and machine. By a separate consideration of sensory processing, cognitive processing, and motory processing it is possible to have a more exact idea of the system element 'man'. The system element 'machine' is well described by differential equations which allow an ergonomical assessment of the manouverability. The knowledge of information processing of man and machine enables a task analysis. This makes appear on one hand the human boundaries depending on the different properties of the task and on the other hand suitable ergonomical solution proposals which improve the reliability of the total system. It is a disadvantage, however, that the change of human reliability by such measures may not be quoted numerically at the moment. (orig.)

  20. Reducing the occurrence of plant events through improved human performance

    International Nuclear Information System (INIS)

    Ross, T.; Burkhart, A.D.

    1993-01-01

    During a routine control room surveillance, the reactor operator is distracted by an alarming secondary annunciator and a telephone call. When the reactor operator resumes the surveillance, he inadvertently performs the procedural steps out of order. This causes a reportable nuclear event. How can procedure-related human performance problems such as this be prevented? The question is vitally important for the nuclear industry. The U.S. Nuclear Regulatory Commission's Office for Analysis and Evaluation of Operational Data observed, open-quotes With the perceived reduction in the number of events caused by equipment failures, INPO and other industry groups and human performance experts agree that a key to continued improvement in plant performance and safety is improved human performance.close quotes In fact, open-quotes more than 50% of the reportable events occurring at nuclear power plants involve human error.close quotes Prevention (or correction) of a human performance problem is normally based on properly balancing the following three factors: (1) supervisory involvement; (2) personnel training; and (3) procedures. The nuclear industry is implementing a formula known as ACME, which better balances supervisory involvement, personnel training, and procedures. Webster's New World Dictionary defines acme as the highest point, the peak. ACME human performance is the goal: ACME Adherence to and use of procedures; Self-Checking; Management Involvement; and Event Investigations

  1. Fucoidan promotes early step of cardiac differentiation from human embryonic stem cells and long-term maintenance of beating areas.

    Science.gov (United States)

    Hamidi, Sofiane; Letourneur, Didier; Aid-Launais, Rachida; Di Stefano, Antonio; Vainchenker, William; Norol, Françoise; Le Visage, Catherine

    2014-04-01

    Somatic stem cells require specific niches and three-dimensional scaffolds provide ways to mimic this microenvironment. Here, we studied a scaffold based on Fucoidan, a sulfated polysaccharide known to influence morphogen gradients during embryonic development, to support human embryonic stem cells (hESCs) differentiation toward the cardiac lineage. A macroporous (pore 200 μm) Fucoidan scaffold was selected to support hESCs attachment and proliferation. Using a protocol based on the cardiogenic morphogen bone morphogenic protein 2 (BMP2) and transforming growth factor (TGFβ) followed by tumor necrosis factor (TNFα), an effector of cardiopoietic priming, we examined the cardiac differentiation in the scaffold compared to culture dishes and embryoid bodies (EBs). At day 8, Fucoidan scaffolds supported a significantly higher expression of the 3 genes encoding for transcription factors marking the early step of embryonic cardiac differentiation NKX2.5 (prelease TGFβ and TNFα was confirmed by Luminex technology. We also found that Fucoidan scaffolds supported the late stage of embryonic cardiac differentiation marked by a significantly higher atrial natriuretic factor (ANF) expression (pstress in the soft hydrogel impaired sarcomere formation, as confirmed by molecular analysis of the cardiac muscle myosin MYH6 and immunohistological staining of sarcomeric α-actinin. Nevertheless, Fucoidan scaffolds contributed to the development of thin filaments connecting beating areas through promotion of smooth muscle cells, thus enabling maintenance of beating areas for up to 6 months. In conclusion, Fucoidan scaffolds appear as a very promising biomaterial to control cardiac differentiation from hESCs that could be further combined with mechanical stress to promote sarcomere formation at terminal stages of differentiation.

  2. Three-dimensional spheroid culture of human umbilical cord mesenchymal stem cells promotes cell yield and stemness maintenance.

    Science.gov (United States)

    Li, Yi; Guo, Gang; Li, Li; Chen, Fei; Bao, Ji; Shi, Yu-Jun; Bu, Hong

    2015-05-01

    Mesenchymal stem cell (MSC) transplantation is a promising treatment of many diseases. However, conventional techniques with cells being cultured as a monolayer result in slow cell proliferation and insufficient yield to meet clinical demands. Three-dimensional (3D) culture systems are gaining attention with regard to recreating a complex microenvironment and to understanding the conditions experienced by cells. Our aim is to establish a novel 3D system for the culture of human umbilical cord MSCs (hUC-MSCs) within a real 3D microenvironment but with no digestion or passaging. Primary hUC-MSCs were isolated and grown in serum-free medium (SFM) on a suspension Rocker system. Cell characteristics including proliferation, phenotype and multipotency were recorded. The therapeutic effects of 3D-cultured hUC-MSCs on carbon tetrachloride (CCl4)-induced acute liver failure in mouse models were examined. In the 3D Rocker system, hUC-MSCs formed spheroids in SFM and maintained high viability and active proliferation. Compared with monolayer culture, the 3D-culture system yielded more hUC-MSCs cells within the same volume. The spheroids expressed higher levels of stem cell markers and displayed stronger multipotency. After transplantation into mouse, 3D hUC-MSCs significantly promoted the secretion of interferon-γ and interleukin-6 but inhibited that of tumor necrosis factor-α, thereby alleviating liver necrosis and promoting regeneration following CCl4 injury. The 3D culture of hUC-MSCs thus promotes cell yield and stemness maintenance and represents a promising strategy for hUC-MSCs expansion on an industrial scale with great potential for cell therapy and biotechnology.

  3. The resist diabetes trial: Rationale, design, and methods of a hybrid efficacy/effectiveness intervention trial for resistance training maintenance to improve glucose homeostasis in older prediabetic adults.

    Science.gov (United States)

    Marinik, Elaina L; Kelleher, Sarah; Savla, Jyoti; Winett, Richard A; Davy, Brenda M

    2014-01-01

    Advancing age is associated with reduced levels of physical activity, increased body weight and fat, decreased lean body mass, and a high prevalence of type 2 diabetes (T2D). Resistance training (RT) increases muscle strength and lean body mass, and reduces risk of T2D among older adults. The Resist Diabetes trial will determine if a social cognitive theory (SCT)-based intervention improves RT maintenance in older, prediabetic adults, using a hybrid efficacy/effectiveness approach. Sedentary, overweight/obese (BMI: 25-39.9 kg/m(2)) adults aged 50-69 (N = 170) with prediabetes (impaired fasting glucose and/or impaired glucose tolerance) completed a supervised 3-month RT (2×/wk) initiation phase and were then randomly assigned (N = 159; 94% retention) to one of two 6-month maintenance conditions: SCT or standard care. The SCT intervention consisted of faded contacts compared to standard care. Participants continue RT at an approved, self-selected community facility during maintenance. A subsequent 6-month period involves no contact for both conditions. Assessments occur at baseline and months 3 (post-initiation), 9 (post-intervention), and 15 (six months after no contact). Primary outcomes are prediabetes indices (i.e., impaired fasting and 2-hour glucose concentration) and strength. Secondary measures include insulin sensitivity, beta-cell responsiveness, and disposition index (oral glucose and C-peptide minimal model); adherence; body composition; and SCT measures. Resist Diabetes is the first trial to examine the effectiveness of a high fidelity SCT-based intervention for maintaining RT in older adults with prediabetes to improve glucose homeostasis. Successful application of SCT constructs for RT maintenance may support translation of our RT program for diabetes prevention into community settings. Copyright © 2013 Elsevier Inc. All rights reserved.

  4. Animal-Assisted Therapy for Improving Human Health

    Directory of Open Access Journals (Sweden)

    Sibel Cevizci

    2009-06-01

    Full Text Available ABSTRACT Animal Assisted Therapy (AAT or Pet Therapy is an adjunctive therapy by taking advantage of human and animal interaction, activate the physiological and psychological mechanisms, initiate positive changes improving health in metabolism. In recent years, this interaction are in use to treat psychological and psychiatric disorders such as stress, depression, loneliness, pervasive developmental disorders affect negatively to human health. Furthermore, AAT has been increasingly used to improve quality of life, hypertension, cardiovascular diseases, chronic illnesses such as cancer and AIDS. The aim of this paper is to identify AAT by reviewing human and animal interaction, evaluate how AAT has a scientific background from past to now. Also, we aim to give some information about the risks, institutional applications, some factors referring AAT’s mechanism of action and chronic diseases, psychological and physical improvements provided with animal assisted therapies. The therapy results will be evaluated more advisable providing AAT is being applied with public health specialist, veterinarian, physician, psychologist, psychiatrist and veterinary public health experts who are monitor applications. Especially, the psychosomatic effects result from physical, emotional and play mechanism of action of HDT can be used for improving quality of life in individuals with chronic diseases. In Turkey, there is no any investigation which have been performed in this scientific field. It is quitely important to evaluate the benefits of this therapy accurately and to select various methods proper to diseases. Consequently, it is obvious that AAT will be considered by the healthcare services as a supportive therapy process for improving human health in Turkey and needs further studies. [TAF Prev Med Bull 2009; 8(3.000: 263-272

  5. Quality Improvement Project to Improve Patient Satisfaction With Pain Management: Using Human-Centered Design.

    Science.gov (United States)

    Trail-Mahan, Tracy; Heisler, Scott; Katica, Mary

    2016-01-01

    In this quality improvement project, our health system developed a comprehensive, patient-centered approach to improving inpatient pain management and assessed its impact on patient satisfaction across 21 medical centers. Using human-centered design principles, a bundle of 6 individual and team nursing practices was developed. Patient satisfaction with pain management, as measured by the Hospital Consumer Assessment of Healthcare Providers and Systems pain composite score, increased from the 25th to just under the 75th national percentile.

  6. The nutrition intervention improved adult human capital and economic productivity.

    Science.gov (United States)

    Martorell, Reynaldo; Melgar, Paul; Maluccio, John A; Stein, Aryeh D; Rivera, Juan A

    2010-02-01

    This article reviews key findings about the long-term impact of a nutrition intervention carried out by the Institute of Nutrition of Central America and Panama from 1969 to 1977. Results from follow-up studies in 1988-89 and 2002-04 show substantial impact on adult human capital and economic productivity. The 1988-89 study showed that adult body size and work capacity increased for those provided improved nutrition through age 3 y, whereas the 2002-04 follow-up showed that schooling was increased for women and reading comprehension and intelligence increased in both men and women. Participants were 26-42 y of age at the time of the 2002-04 follow-up, facilitating the assessment of economic productivity. Wages of men increased by 46% in those provided with improved nutrition through age 2 y. Findings for cardiovascular disease risk factors were heterogeneous; however, they suggest that improved nutrition in early life is unlikely to increase cardiovascular disease risk later in life and may indeed lower risk. In conclusion, the substantial improvement in adult human capital and economic productivity resulting from the nutrition intervention provides a powerful argument for promoting improvements in nutrition in pregnant women and young children.

  7. Integrated maintenance program (IMP)

    International Nuclear Information System (INIS)

    Zemdegs, R.T.; Chout, Q.B.

    1998-01-01

    Approaches to the maintenance of nuclear power plants have undergone significant change in the past several decades. The traditional breakdown approach has been displaced by preventive (calendar-based) maintenance and more recently, by condition-based maintenance (CBM). This is largely driven by the fact that traditional maintenance programs, derived primarily from equipment vendor recommendations, are generally unsuccessful in controlling maintenance costs or equipment failures. Many advances in the maintenance field have taken place since the maintenance plans for Ontario Hydro's nuclear plants were initially established. Ontario Hydro nuclear plant operating costs can be substantially reduced and Incapability Factor improved with the application of modern maintenance processes and tools. Pickering is designated as the lead station for IMP. Of immediate concern is the fact that Pickering Nuclear Division has been experiencing a significant backlog of Operating Preventive Maintenance Callups. This backlog, over 2000, is unacceptable to both station management and the nuclear regulator, the Atomic Energy Control Board. In addition there are over 500 callups in various stages of revision (in hyperspace) without an adequate control nor reporting system to manage their completion. There is also considerable confusion about the classification of l icensing c allups, e.g. callups which are mandatory as a result of legal requirements. Furthermore the ineffectiveness of the Preventive Maintenance (PM) has been the subject of peer audits and Atomic Energy Control Board (AECB) findings over the past several years. The current preventive maintenance ratio PM2 /(PM+CM3) at Pickering ND is less than 20%, due to the current high load of equipment breakdown. This past summer, an Independent Integrated Performance Assessment (IIPA) review at Ontario Hydro confirmed these concerns. Over the past several years, Ontario Hydro nuclear staff have evaluated several programs to improve

  8. Improving Saliency Models by Predicting Human Fixation Patches

    KAUST Repository

    Dubey, Rachit

    2015-04-16

    There is growing interest in studying the Human Visual System (HVS) to supplement and improve the performance of computer vision tasks. A major challenge for current visual saliency models is predicting saliency in cluttered scenes (i.e. high false positive rate). In this paper, we propose a fixation patch detector that predicts image patches that contain human fixations with high probability. Our proposed model detects sparse fixation patches with an accuracy of 84 % and eliminates non-fixation patches with an accuracy of 84 % demonstrating that low-level image features can indeed be used to short-list and identify human fixation patches. We then show how these detected fixation patches can be used as saliency priors for popular saliency models, thus, reducing false positives while maintaining true positives. Extensive experimental results show that our proposed approach allows state-of-the-art saliency methods to achieve better prediction performance on benchmark datasets.

  9. Improving Saliency Models by Predicting Human Fixation Patches

    KAUST Repository

    Dubey, Rachit; Dave, Akshat; Ghanem, Bernard

    2015-01-01

    There is growing interest in studying the Human Visual System (HVS) to supplement and improve the performance of computer vision tasks. A major challenge for current visual saliency models is predicting saliency in cluttered scenes (i.e. high false positive rate). In this paper, we propose a fixation patch detector that predicts image patches that contain human fixations with high probability. Our proposed model detects sparse fixation patches with an accuracy of 84 % and eliminates non-fixation patches with an accuracy of 84 % demonstrating that low-level image features can indeed be used to short-list and identify human fixation patches. We then show how these detected fixation patches can be used as saliency priors for popular saliency models, thus, reducing false positives while maintaining true positives. Extensive experimental results show that our proposed approach allows state-of-the-art saliency methods to achieve better prediction performance on benchmark datasets.

  10. Human Resources and Innovative Behaviour : Improving Nursing Performance

    OpenAIRE

    Xerri, Matthew; Reid, Stuart

    2017-01-01

    This study examines, using the social exchange theory, the mediating effect of employees’ perception of wellbeing on the relationship between two human resource (HR) management factors (satisfaction with teamwork and satisfaction with training opportunities) and innovative behaviour of nurses working in Australian public and private hospitals. Current nurse shortages and limited budgets have increased the need for hospitals to improve their efficiency and cost-effectiveness. It is proposed th...

  11. INTEGRATION MECHANISMS OF IMPROVEMENT OF HUMAN RESOURCES MANAGEMENT

    Directory of Open Access Journals (Sweden)

    Vera A. Akimenko

    2013-01-01

    Full Text Available In the current economic conditions, the efficiency of business processes of an organization is determined by the quality of the staff. Therefore, actual is the creation and application of new approaches to the management of human re-sources. The article presents a comparative analysis of management practices and their impact on the effectiveness of personnel management, the mechanism of their integration to improve the efficiency of the process.

  12. Improvement of hydration and epidermal barrier function in human skin by a novel compound isosorbide dicaprylate.

    Science.gov (United States)

    Chaudhuri, R K; Bojanowski, K

    2017-10-01

    The study involved the synthesis of a novel derivative of caprylic acid - isosorbide dicaprylate (IDC) - and the evaluation of its potential in improving water homoeostasis and epidermal barrier function in human skin. The effect of IDC on gene expression was assayed in skin organotypic cultures by DNA microarrays. The results were then confirmed for a few key genes by quantitative PCR, immuno- and cytochemistry. Final validation of skin hydration properties was obtained by four separate clinical studies. Level of hydration was measured by corneometer either by using 2% IDC lotion alone vs placebo or in combination with 2% glycerol lotion vs 2% glycerol only. A direct comparison in skin hydration between 2% IDC and 2% glycerol lotions was also carried out. The epidermal barrier function improvement was assessed by determining changes in transepidermal water loss (TEWL) on the arms before and after treatment with 2% IDC lotion versus placebo. IDC was found to upregulate the expression of AQP3, CD44 and proteins involved in keratinocyte differentiation as well as the formation and function of stratum corneum. A direct comparison between 2% IDC versus 2% glycerol lotions revealed a three-fold advantage of IDC in providing skin hydration. Severely dry skin treated with 2% IDC in combination with 2% glycerol showed 133% improvement, whereas 35% improvement was observed with moderately dry human skin. Topical isosorbide dicaprylate favourably modulates genes involved in the maintenance of skin structure and function, resulting in superior clinical outcomes. By improving skin hydration and epidermal permeability barrier, it offers therapeutic applications in skin ageing. © 2017 Society of Cosmetic Scientists and the Société Française de Cosmétologie.

  13. Developing and improving human capital and productivity in public companies

    Directory of Open Access Journals (Sweden)

    Nozipho Sithole

    2016-08-01

    Full Text Available This article assesses the impact of the Assisted Education Programme (AEP in developing, improving human capital and productivity specifically for eThekwini Municipality employee human resource. This programme offers funding to employees to further their studies in higher learning institutions, which are in partnership with and recognized by eThekwini Municipality. The core function of this programme is to improve and develop employee capabilities in order to enhance municipal productivity. However, different factors have prohibited the programme from reaching required funding polity objectives. Participants filled in questionnaires and from them data were collected. The study used quantitative research as a method of research. The target population for this study consisted of 100 participants. The study sample size were 64 participants which were randomly selected out of the Durban Solid Waste Unit, specifically general assistants. The study analyzed data using SPSS (version 23.0. A significant percentage of respondents indicated to a lack of transparency and poor consistency in the process of awarding the funding and to insufficient information, which detailed the criteria for eligibility of applicants. Henceforth, the study concluded that municipal employee underutilized the AEP because of being ill informed about it. This resulted in the employee perception that the programme had little or no benefit to them and that it had no value in improving their human capital development. This finding is shown by a Chi-square goodness of fit test to be statistically significant (std=1.49150; mean=2.7500; p=.000

  14. Improvement of human reliability analysis method for PRA

    International Nuclear Information System (INIS)

    Tanji, Junichi; Fujimoto, Haruo

    2013-09-01

    It is required to refine human reliability analysis (HRA) method by, for example, incorporating consideration for the cognitive process of operator into the evaluation of diagnosis errors and decision-making errors, as a part of the development and improvement of methods used in probabilistic risk assessments (PRAs). JNES has been developed a HRA method based on ATHENA which is suitable to handle the structured relationship among diagnosis errors, decision-making errors and operator cognition process. This report summarizes outcomes obtained from the improvement of HRA method, in which enhancement to evaluate how the plant degraded condition affects operator cognitive process and to evaluate human error probabilities (HEPs) which correspond to the contents of operator tasks is made. In addition, this report describes the results of case studies on the representative accident sequences to investigate the applicability of HRA method developed. HEPs of the same accident sequences are also estimated using THERP method, which is most popularly used HRA method, and comparisons of the results obtained using these two methods are made to depict the differences of these methods and issues to be solved. Important conclusions obtained are as follows: (1) Improvement of HRA method using operator cognitive action model. Clarification of factors to be considered in the evaluation of human errors, incorporation of degraded plant safety condition into HRA and investigation of HEPs which are affected by the contents of operator tasks were made to improve the HRA method which can integrate operator cognitive action model into ATHENA method. In addition, the detail of procedures of the improved method was delineated in the form of flowchart. (2) Case studies and comparison with the results evaluated by THERP method. Four operator actions modeled in the PRAs of representative BWR5 and 4-loop PWR plants were selected and evaluated as case studies. These cases were also evaluated using

  15. Design and evaluation of augmented reality for nuclear power plant maintenance based on Cognitive activity analysis

    International Nuclear Information System (INIS)

    Koo, Jwa Jin

    2008-02-01

    The goals of maintenance in nuclear power plants (NPPs) are to reduce the number of plant shutdowns, to decrease the shutdown time, to minimize the maintenance costs, and to improve nuclear safety. Furthermore, it is difficult for maintenance personnel to conduct work in NPPs due to the complexity of NPPs, safety issues and time constraints. Human errors should be prevented to achieve maintenance goals in NPPs. Therefore, it is necessary to improve working conditions by introducing support systems. Augmented Reality (AR) has the potential to assist with maintenance tasks and make maintenance personnel concentrate on the tasks, which will then the reduced human error and improve human performance. The working procedure for AR systems was designed based on the characteristics of cognitive activity, and an experiment was conducted to estimate the effectiveness of AR. The results indicated that a well-designed working procedure for AR systems was more effective than a conventional paper-based working procedure. In addition, participants made fewer errors using the designed working procedure. AR systems as maintenance support systems are beneficial technology that can improve maintenance performance by reducing cognitive loads and unnecessary movements. An AR application can be attractive and effective at supporting maintenance task

  16. An Improved AAM Method for Extracting Human Facial Features

    Directory of Open Access Journals (Sweden)

    Tao Zhou

    2012-01-01

    Full Text Available Active appearance model is a statistically parametrical model, which is widely used to extract human facial features and recognition. However, intensity values used in original AAM cannot provide enough information for image texture, which will lead to a larger error or a failure fitting of AAM. In order to overcome these defects and improve the fitting performance of AAM model, an improved texture representation is proposed in this paper. Firstly, translation invariant wavelet transform is performed on face images and then image structure is represented using the measure which is obtained by fusing the low-frequency coefficients with edge intensity. Experimental results show that the improved algorithm can increase the accuracy of the AAM fitting and express more information for structures of edge and texture.

  17. Data management in maintenance outsourcing

    International Nuclear Information System (INIS)

    Murthy, D.N.P.; Karim, M.R.; Ahmadi, A.

    2015-01-01

    Most businesses view maintenance as tasks carried out by technicians and the data collected is mostly cost related. There is a growing trend towards outsourcing of maintenance and the data collection issues are not addressed properly in most maintenance service contracts. Effective maintenance management requires proper data management - data collection and analysis for decision-making. This requires a proper framework and when maintenance is outsourced it raises several issues and challenges. The paper develops a framework for data management when maintenance is outsourced and looks at a real case study that highlights the need for proper data management. - Highlights: • Framework for data management in maintenance outsourcing. • Black-box to grey-box approaches for modelling. • Improvements to maintenance decision-making. • Case study to illustrate the approaches and the shortcomings in data collection

  18. International Atomic Energy Agency specialists meeting on experience in ageing, maintenance, and modernization of instrumentation and control systems for improving nuclear power plant availability

    Energy Technology Data Exchange (ETDEWEB)

    1993-10-01

    This report presents the proceedings of the Specialist`s Meeting on Experience in Aging, Maintenance and Modernization of Instrumentation and Control Systems for Improving Nuclear Power Plant Availability that was held at the Ramada Inn in Rockville, Maryland on May 5--7, 1993. The Meeting was presented in cooperation with the Electric Power Research Institute, Oak Ridge National Laboratory and the International Atomic Energy Agency. There were approximately 65 participants from 13 countries at the Meeting. Individual reports have been cataloged separately.

  19. Improvement of availability of PWR nuclear plants through the reduction of the time required for refueling/maintenance outages, Phase 1. Final report

    International Nuclear Information System (INIS)

    Thompson, C.A.

    1978-08-01

    The objective of this project is to identify improvements in procedures and equipment which will reduce the time required for refueling/maintenance outages at PWR nuclear power plants. The outage of Commonwealth Edison Zion Station Unit 1 in March through May of 1976 was evaluated to identify those items which caused delays and those work activities that offer the potential for significant improvements toward reducing its overall duration. Thus, the plant's availability for power production would be increased. Revisions in procedures and some equipment modifications were implemented and evaluated during the Zion Unit 2 refueling/maintenance outage beginning in January 1977. Analysis of the observed data has identified benefits available through improved refueling equipment and also areas where additional new, innovative refueling, or refueling-related equipment should be beneficial. A number of specific design concepts are recommended as a result of Phase 1. In addition, a new master planning mechanism is described for implementation during subsequent planned outages at Zion Station. This final report describes the recommended conceptual designs and planning mechanism and assesses their impact upon future outages. Their effect on savings in refueling time, labor, and radiation exposure is discussed. The estimated economic payoff for these concepts was found to be of such significance that an additional phase of the program is warranted. During this extended phase, a more detailed engineering study should be undertaken to determine the cost of implementation along with more specific estimates of the benefits for PWR plants already in operation or under construction

  20. New method of classifying human errors at nuclear power plants and the analysis results of applying this method to maintenance errors at domestic plants

    International Nuclear Information System (INIS)

    Takagawa, Kenichi; Miyazaki, Takamasa; Gofuku, Akio; Iida, Hiroyasu

    2007-01-01

    Since many of the adverse events that have occurred in nuclear power plants in Japan and abroad have been related to maintenance or operation, it is necessary to plan preventive measures based on detailed analyses of human errors made by maintenance workers or operators. Therefore, before planning preventive measures, we developed a new method of analyzing human errors. Since each human error is an unsafe action caused by some misjudgement made by a person, we decided to classify them into six categories according to the stage in the judgment process in which the error was made. By further classifying each error into either an omission-type or commission-type, we produced 12 categories of errors. Then, we divided them into the two categories of basic error tendencies and individual error tendencies, and categorized background factors into four categories: imperfect planning; imperfect facilities or tools; imperfect environment; and imperfect instructions or communication. We thus defined the factors in each category to make it easy to identify factors that caused the error. Then using this method, we studied the characteristics of human errors that involved maintenance workers and planners since many maintenance errors have occurred. Among the human errors made by workers (worker errors) during the implementation stage, the following three types were prevalent with approximately 80%: commission-type 'projection errors', omission-type comprehension errors' and commission type 'action errors'. The most common among the individual factors of worker errors was 'repetition or habit' (schema), based on the assumption of a typical situation, and the half number of the 'repetition or habit' cases (schema) were not influenced by any background factors. The most common background factor that contributed to the individual factor was 'imperfect work environment', followed by 'insufficient knowledge'. Approximately 80% of the individual factors were 'repetition or habit' or

  1. Instrumentation maintenance

    International Nuclear Information System (INIS)

    Mack, D.A.

    1976-09-01

    It is essential to any research activity that accurate and efficient measurements be made for the experimental parameters under consideration for each individual experiment or test. Satisfactory measurements in turn depend upon having the necessary instruments and the capability of ensuring that they are performing within their intended specifications. This latter requirement can only be achieved by providing an adequate maintenance facility, staffed with personnel competent to understand the problems associated with instrument adjustment and repair. The Instrument Repair Shop at the Lawrence Berkeley Laboratory is designed to achieve this end. The organization, staffing and operation of this system is discussed. Maintenance policy should be based on studies of (1) preventive vs. catastrophic maintenance, (2) records indicating when equipment should be replaced rather than repaired and (3) priorities established to indicate the order in which equipment should be repaired. Upon establishing a workable maintenance policy, the staff should be instructed so that they may provide appropriate scheduled preventive maintenance, calibration and corrective procedures, and emergency repairs. The education, training and experience of the maintenance staff is discussed along with the organization for an efficient operation. The layout of the various repair shops is described in the light of laboratory space and financial constraints

  2. Evidence for a double dissociation of articulatory rehearsal and non-articulatory maintenance of phonological information in human verbal working memory.

    Science.gov (United States)

    Trost, Sarah; Gruber, Oliver

    2012-01-01

    Recent functional neuroimaging studies have provided evidence that human verbal working memory is represented by two complementary neural systems, a left lateralized premotor-parietal network implementing articulatory rehearsal and a presumably phylogenetically older bilateral anterior-prefrontal/inferior-parietal network subserving non-articulatory maintenance of phonological information. In order to corroborate these findings from functional neuroimaging, we performed a targeted behavioural study in patients with very selective and circumscribed brain lesions to key regions suggested to support these different subcomponents of human verbal working memory. Within a sample of over 500 neurological patients assessed with high-resolution structural magnetic resonance imaging, we identified 2 patients with corresponding brain lesions, one with an isolated lesion to Broca's area and the other with a selective lesion bilaterally to the anterior middle frontal gyrus. These 2 patients as well as groups of age-matched healthy controls performed two circuit-specific verbal working memory tasks. In this way, we systematically assessed the hypothesized selective behavioural effects of these brain lesions on the different subcomponents of verbal working memory in terms of a double dissociation. Confirming prior findings, the lesion to Broca's area led to reduced performance under articulatory rehearsal, whereas the non-articulatory maintenance of phonological information was unimpaired. Conversely, the bifrontopolar brain lesion was associated with impaired non-articulatory phonological working memory, whereas performance under articulatory rehearsal was unaffected. The present experimental neuropsychological study in patients with specific and circumscribed brain lesions confirms the hypothesized double dissociation of two complementary brain systems underlying verbal working memory in humans. In particular, the results demonstrate the functional relevance of the anterior

  3. Use of Human Reliability Insights to Improve Decision-Making

    International Nuclear Information System (INIS)

    Julius, J. A.; Moieni, P.; Grobbelaar, J.; Kohlhepp, K.

    2016-01-01

    This paper describes the use of insights obtained during the development and application of human reliability analysis (HRA) as part of a probabilistic risk assessment (PRA) to support decision-making, including improvements to operations, training, and safety culture. Insights have been gained from the development and application of HRA as part of a PRA for nuclear power plants in the USA, Europe and Asia over the last two decades. These models consist of Level 1 and Level 2 PRA models of internal and external events, during full power and shutdown modes of plant operation. These insights include the use of human factors information to improve the qualitative portion of the HRA. The subsequent quantification in the HRA effectively prioritises the contributors to the unreliability of operator actions, and the process facilitates the identification of the factors that are important to the success of the operator actions. Additionally, the tools and techniques also allow for the evaluation of key assumptions and sources of uncertainty. The end results have been used to effectively support decision-making for day-to-day plant operations as well as licensing issues. HRA results have been used to provide feedback and improvements to plant procedures, operator training and other areas contributing the plant safety culture. Examples of the types of insights are presented in this paper. (author)

  4. Improving human performance: Industry factors influencing the ability to perform

    Directory of Open Access Journals (Sweden)

    Güera Massyn Romo

    2013-03-01

    Full Text Available Learning interventions and new technologies that aim to improve human performance must take cognisance of industry factors inhibiting human performance. The dynamic and fast pace nature of the Information and Communication Technologies (ICT and the engineering industries do not lend themselves to proper skills planning and management. These industries experience real skills gaps, to some of which they contribute by themselves. This study reports on these performance-inhibiting factors such as the underutilisation of available skills, tolerance for individual preferences, and dynamically, and informally refining a role objective while an employee is occupying a certain role. The important professional skills required by individuals to cope with these real life factors are also explored in the skills gaps management context. Moreover, these industries need a profile they refer to as Special Forces, which denotes a high calibre of worker that possesses well-developed professional skills whilst having advanced technical expertise and sufficient experience. This resource profile is required largely due to the poor management of human resource processes in practice and the current reported lack of adequate skills. Furthermore, this study refers to the recent lack of a working definition for these Special Forces leading to the omitted active development of these profiles in industry today, which appears to become a key human performance inhibiting factor.

  5. Managed maintenance, the next step in power plant maintenance

    International Nuclear Information System (INIS)

    Butterworth, G.; Anderson, T.M.

    1984-01-01

    The Westinghouse Nuclear Services Integration Division managed maintenance services are described. Essential to the management and control of a total plant maintenance programme is the development of a comprehensive maintenance specification. During recent years Westinghouse has jointly developed total plant engineering-based maintenance specifications with a number of utilities. The process employed and the experience to date are described. To efficiently implement the maintenance programme Westinghouse has developed a computer software program specifically designed for day to day use at the power plant by maintenance personnel. This program retains an equipment maintenance history, schedules maintenance activities, issues work orders and performs a number of sophisticated analyses of the maintenance backlog and forecast, equipment failure rates, etc. The functions of this software program are described and details of Westinghouse efforts to support the utilities in reducing outage times through development of predefined outage plans for critical report maintenance activities are given. Also described is the experience gained in the training of specialized maintenance personnel, employing competency-based training techniques and equipment mock-ups, and the benefits experienced, in terms of improved quality and productivity of maintenance performed. The success experienced with these methods has caused Westinghouse to expand the use of these training techniques to the more routine skill areas of power plant maintenance. A significant reduction in the operating costs of nuclear power plants will only be brought about by a significant improvement in the quality of maintenance. Westinghouse intends to effect this change by expanding its international service capabilities and to make major investments in order to promote technological developments in the area of power plant maintenance. (author)

  6. Maintenance: Two Views.

    Science.gov (United States)

    Ballard, J. Barry; Burdette, Clarence E.

    1987-01-01

    Presents two viewpoints on the question of using funding from the Vocational Education Act to maintain ongoing vocational programs. Ballard argues that programs have improved qualitatively because of additional program improvement monies, whereas Burdette argues that the ban on using funds for maintenance treats some states unfairly. (CH)

  7. Human-centred radiological software techniques supporting improved nuclear safety

    International Nuclear Information System (INIS)

    Szoeke, Istvan; Johnsen, Terje

    2013-01-01

    The Institute for Energy Technology (IFE) is an international research foundation for energy and nuclear technology. IFE is also the host for the international OECD Halden Reactor Project. The Software Engineering Department in the Man Technology Organisation at IFE is a leading international centre of competence for the development and evaluation of human-centred technologies, process visualisation, and the lifecycle of high integrity software important to safety. This paper is an attempt to give a general overview of the current, and some of the foreseen, research and development of human-centred radiological software technologies at the Software Engineering department to meet with the need of improved radiological safety for not only nuclear industry but also other industries around the world. (author)

  8. Interval of Routine Maintenance and Maintenance Performance: A Literature Review

    Directory of Open Access Journals (Sweden)

    Au-Yong Cheong Peng

    2016-01-01

    Full Text Available In high-rise residential buildings, the quality of facilities management services is significant to the normal operation of the facilities. Unfortunately, lack of concern towards building maintenance, especially preventive maintenance, happens in domestic housing industry in Malaysia. Majority of the maintenance operations of condominiums suffer from lack of planning, lack of proactive maintenance plan, and lack of proper implementation. Thus, this paper reviews the implementation of preventive maintenance strategy, routine maintenance in specific. An extensive review of literature published in 1987 to 2014 is performed for the purpose of this research. The publications are sourced from journal articles, conference proceedings and books. The literature analysis confirms that the routine maintenance of facilities and building services is vital and it can be influential towards the maintenance performance. Subsequently, a theoretical framework is developed, which shows the relationship between routine maintenance of building facilities & services and maintenance performance. The building facilities & services are divided into two categories. They are essential facilities & services that ensure the safety, health, habitability, and operability of buildings; while value-added facilities & services deal with property value, return on investment, and quality living of buildings. Based on the findings, a future research is proposed, which aims to identify the appropriate routine of maintenance for the facilities and services in high-rise residential buildings to improve the maintenance performance.

  9. Dr. Mainte. Integrated simulator of maintenance optimization of LWRs

    International Nuclear Information System (INIS)

    Isobe, Yoshihiro; Sagisaka, Mitsuyuki; Etoh, Junji; Matsunaga, Takashi; Kosaka, Toru; Matsumoto, Satoshi; Yoshimura, Shinobu

    2014-01-01

    Dr. Mainte, an integrated simulator for maintenance optimization of LWRs (Light Water Reactors) has been developed based on PFM (Probabilistic Fracture Mechanics) analyses. The concept of the simulator is to provide a decision-making system to optimize maintenance activities for representative components and piping systems in nuclear power plants totally and quantitatively in terms of safety, availability and economic efficiency, environmental impact and social acceptance. For the further improvement of the safety and availability, the effect of human error and its reduction on the optimization of plant maintenance activities and approaches of reducing it have been studied. (author)

  10. Airline Maintenance Manpower Optimization from the De Novo Perspective

    Science.gov (United States)

    Liou, James J. H.; Tzeng, Gwo-Hshiung

    Human resource management (HRM) is an important issue for today’s competitive airline marketing. In this paper, we discuss a multi-objective model designed from the De Novo perspective to help airlines optimize their maintenance manpower portfolio. The effectiveness of the model and solution algorithm is demonstrated in an empirical study of the optimization of the human resources needed for airline line maintenance. Both De Novo and traditional multiple objective programming (MOP) methods are analyzed. A comparison of the results with those of traditional MOP indicates that the proposed model and solution algorithm does provide better performance and an improved human resource portfolio.

  11. NAPUS 2000 Rapeseed (Brassica napus breeding for improved human nutrition

    Directory of Open Access Journals (Sweden)

    Friedt Wolfgang

    2001-01-01

    Full Text Available Following a competition announcement of the Federal Ministry of Research and Education (BMBF a project dealing with the improvement of the nutritional value of oilseed rape (Brassica napus for food applications and human nutrition was worked out and started in autumn 1999. A number of partners (Figure 2 are carrying out a complex project reaching from the discovery, characterisation, isolation and transfer of genes of interest up to breeding of well performing varieties combined with important agronomic traits. Economic studies and processing trials as well as nutritional investigations of the new qualities are undertaken. B. napus seed quality aspects with respect to seed coat colour, oil composition, lecithin and protein fractions and antioxidants like tocopherols and resveratrol will be improved.

  12. Improvement of human operator vibroprotection system in the utility machine

    Science.gov (United States)

    Korchagin, P. A.; Teterina, I. A.; Rahuba, L. F.

    2018-01-01

    The article is devoted to an urgent problem of improving efficiency of road-building utility machines in terms of improving human operator vibroprotection system by determining acceptable values of the rigidity coefficients and resistance coefficients of operator’s cab suspension system elements and those of operator’s seat. Negative effects of vibration result in labour productivity decrease and occupational diseases. Besides, structure vibrations have a damaging impact on the machine units and mechanisms, which leads to reducing an overall service life of the machine. Results of experimental and theoretical research of operator vibroprotection system in the road-building utility machine are presented. An algorithm for the program to calculate dynamic impacts on the operator in terms of different structural and performance parameters of the machine and considering combination of external pertrubation influences was proposed.

  13. Excellence through maintenance mastering

    International Nuclear Information System (INIS)

    Lamarche, M.; Guillot, M.; Monier, M.

    1987-01-01

    To improve the overall availability factor of nuclear power plants you have to cut either the forced outage role and the planned outage time or you need to reduce simultaneously the failures and the efforts devoted to avoiding them. Among other results, this goal leads to a decrease in the number of real or anticipated problems. Electricite de France policy, in this matter, is to focus on decreasing the compoents' maintenance needs through a comprehensive modification program, targeted to eliminating the weak points as revealed by the operation. Thereby one may reach, for simple equipment, a nearly maintenance-free condition in which the only maintenance needed is surveillance, which provides assurance that everything is operating properly. A good example of this type of equipment is the family of static components, drums, and pipes whose corrective maintenance is almost nil when their initial condition is good

  14. A collaborative brain-computer interface for improving human performance.

    Directory of Open Access Journals (Sweden)

    Yijun Wang

    Full Text Available Electroencephalogram (EEG based brain-computer interfaces (BCI have been studied since the 1970s. Currently, the main focus of BCI research lies on the clinical use, which aims to provide a new communication channel to patients with motor disabilities to improve their quality of life. However, the BCI technology can also be used to improve human performance for normal healthy users. Although this application has been proposed for a long time, little progress has been made in real-world practices due to technical limits of EEG. To overcome the bottleneck of low single-user BCI performance, this study proposes a collaborative paradigm to improve overall BCI performance by integrating information from multiple users. To test the feasibility of a collaborative BCI, this study quantitatively compares the classification accuracies of collaborative and single-user BCI applied to the EEG data collected from 20 subjects in a movement-planning experiment. This study also explores three different methods for fusing and analyzing EEG data from multiple subjects: (1 Event-related potentials (ERP averaging, (2 Feature concatenating, and (3 Voting. In a demonstration system using the Voting method, the classification accuracy of predicting movement directions (reaching left vs. reaching right was enhanced substantially from 66% to 80%, 88%, 93%, and 95% as the numbers of subjects increased from 1 to 5, 10, 15, and 20, respectively. Furthermore, the decision of reaching direction could be made around 100-250 ms earlier than the subject's actual motor response by decoding the ERP activities arising mainly from the posterior parietal cortex (PPC, which are related to the processing of visuomotor transmission. Taken together, these results suggest that a collaborative BCI can effectively fuse brain activities of a group of people to improve the overall performance of natural human behavior.

  15. Improvements for extending the time between maintenance periods for the Heidelberg ion beam therapy center (HIT) ion sources

    Energy Technology Data Exchange (ETDEWEB)

    Winkelmann, Tim, E-mail: tim.winkelmann@med.uni-heidelberg.de; Cee, Rainer; Haberer, Thomas; Naas, Bernd; Peters, Andreas; Schreiner, Jochen [Heidelberger Ionenstrahl-Therapie Centrum (HIT), D -69120 Heidelberg (Germany)

    2014-02-15

    The clinical operation at the Heidelberg Ion Beam Therapy Center (HIT) started in November 2009; since then more than 1600 patients have been treated. In a 24/7 operation scheme two 14.5 GHz electron cyclotron resonance ion sources are routinely used to produce protons and carbon ions. The modification of the low energy beam transport line and the integration of a third ion source into the therapy facility will be shown. In the last year we implemented a new extraction system at all three sources to enhance the lifetime of extraction parts and reduce preventive and corrective maintenance. The new four-electrode-design provides electron suppression as well as lower beam emittance. Unwanted beam sputtering effects which typically lead to contamination of the insulator ceramics and subsequent high-voltage break-downs are minimized by the beam guidance of the new extraction system. By this measure the service interval can be increased significantly. As a side effect, the beam emittance can be reduced allowing a less challenging working point for the ion sources without reducing the effective beam performance. This paper gives also an outlook to further enhancements at the HIT ion source testbench.

  16. How social information can improve estimation accuracy in human groups.

    Science.gov (United States)

    Jayles, Bertrand; Kim, Hye-Rin; Escobedo, Ramón; Cezera, Stéphane; Blanchet, Adrien; Kameda, Tatsuya; Sire, Clément; Theraulaz, Guy

    2017-11-21

    In our digital and connected societies, the development of social networks, online shopping, and reputation systems raises the questions of how individuals use social information and how it affects their decisions. We report experiments performed in France and Japan, in which subjects could update their estimates after having received information from other subjects. We measure and model the impact of this social information at individual and collective scales. We observe and justify that, when individuals have little prior knowledge about a quantity, the distribution of the logarithm of their estimates is close to a Cauchy distribution. We find that social influence helps the group improve its properly defined collective accuracy. We quantify the improvement of the group estimation when additional controlled and reliable information is provided, unbeknownst to the subjects. We show that subjects' sensitivity to social influence permits us to define five robust behavioral traits and increases with the difference between personal and group estimates. We then use our data to build and calibrate a model of collective estimation to analyze the impact on the group performance of the quantity and quality of information received by individuals. The model quantitatively reproduces the distributions of estimates and the improvement of collective performance and accuracy observed in our experiments. Finally, our model predicts that providing a moderate amount of incorrect information to individuals can counterbalance the human cognitive bias to systematically underestimate quantities and thereby improve collective performance. Copyright © 2017 the Author(s). Published by PNAS.

  17. Recent Changes to ABR Maintenance of Certification Part 4 (PQI): Acknowledgment of Radiologists' Activities to Improve Quality and Safety.

    Science.gov (United States)

    Donnelly, Lane F; Mathews, Vincent P; Laszakovits, David J; Jackson, Valerie P; Guiberteau, Milton J

    2016-02-01

    The ABR has recently reviewed and revised its policy establishing how ABR diplomates may comply with requirements for Maintenance of Certification Part 4: Practice Quality Improvement (PQI). The changes were deemed necessary by the Board of Trustees to acknowledge and credit the numerous ways in which radiology professionals contribute to improving patient care through existing and evolving activities available to them within the radiology community. In addition to meeting requirements by completing a traditional PQI project, the policy revision now allows diplomates to meet criteria by completing one of a number of activities in an expanded spectrum of PQI options recognized by the ABR. The new policy also acknowledges the maturing state of quality improvement science by permitting PQI projects to use "any standard quality improvement methodology," such as Six Sigma, Lean, the Institute for Healthcare Improvement's Model for Improvement, and others in addition to the previously prescribed three-phase plan-do-study-act format. Copyright © 2016 American College of Radiology. Published by Elsevier Inc. All rights reserved.

  18. Effectively managing nuclear risk through human performance improvement

    International Nuclear Information System (INIS)

    Coe, R.P.

    2004-01-01

    Full text: The US commercial nuclear industry has just completed an outstanding decade of plant performance. Safety levels and electric production are at unprecedented high levels and continue to exceed even high industry goals. Nuclear energy continues to keep the highest priority on performance improvement programs and highly trained/qualified people that maintain its record setting safety and reliability of operations. While the industry has maintained a consistently high level of performance, the advent of deregulation and the consolidation of NPP ownership, as well as the current climate of concern about both rising energy costs and availability of power, has raised the standard for nuclear energy's level of competitiveness in today's market place. The resulting challenge is how to more effectively manage risk and improve performance even further in a generally high performing organization. Newer technology and more training by themselves are not the answer. Rather, the answer will lie in the human side of the organization and management's ability to tap into the unused potential of employee commitment and productivity. It is people who offer the greatest potential for organizational success. Given the fact that human performance has been demonstrated to yield higher rates of return than physical capital, it makes good business sense to determine how to encourage the behaviors in the workplace to manage the risk that will accompany efforts to boost the nuclear industry to new heights of excellence. This means effectively developing a performance improvement culture through identifying measurable performance indicators and determining how behaviors can best be influenced to improve those indicators. It also means seeing a culture of performance improvement and risk management as a strategic planning tool rather than a solution to a particular problem. One of the most effective ways to develop this culture of performance improvement and effectively managing risk

  19. Trehalose improves cell proliferation and dehydration tolerance of human HaCaT cells

    Directory of Open Access Journals (Sweden)

    Lee Kyung Eun

    2015-01-01

    Full Text Available Trehalose is a disaccharide molecule that serves as a natural osmotic regulator in halophilic microorganisms and plants but not in mammals. We observed that human HaCaT cells supplied with trehalose improved cell proliferation and extended viability under dehydration. In HaCaT cells, in response to increasing concentrations of exogenous trehalose, the levels of heat shock protein (HSP 70 increased and matrix metalloproteinase (MMP 1 decreased. Proteome analysis of trehalose-treated HaCaT cells revealed remarkable increases in the levels of proteins involved in cell signaling and the cell cycle, including p21 activated kinase I, Sec I family domain protein and elongation factor G. Moreover, the proteins for cell stress resistance, tryptophan hydroxylase, serine/cysteine proteinase inhibitors and vitamin D receptors were also increased. In addition, the proteins responsible for the maintenance of the cytoskeleton and cellular structures including procollagen-lysine dioxygenase, vinculin and ezrin were increased. Proteomic data revealed that trehalose affected HaCaT cells by inducing the proteins involved in cell proliferation. These results suggest that trehalose improves the proliferation and dehydration tolerance of HaCaT cells by inducing proteins involved in cell growth and dehydration protection.

  20. Applying human rights to improve access to reproductive health services.

    Science.gov (United States)

    Shaw, Dorothy; Cook, Rebecca J

    2012-10-01

    Universal access to reproductive health is a target of Millennium Development Goal (MDG) 5B, and along with MDG 5A to reduce maternal mortality by three-quarters, progress is currently too slow for most countries to achieve these targets by 2015. Critical to success are increased and sustainable numbers of skilled healthcare workers and financing of essential medicines by governments, who have made political commitments in United Nations forums to renew their efforts to reduce maternal mortality. National essential medicine lists are not reflective of medicines available free or at cost in facilities or in the community. The WHO Essential Medicines List indicates medicines required for maternal and newborn health including the full range of contraceptives and emergency contraception, but there is no consistent monitoring of implementation of national lists through procurement and supply even for basic essential drugs. Health advocates are using human rights mechanisms to ensure governments honor their legal commitments to ensure access to services essential for reproductive health. Maternal mortality is recognized as a human rights violation by the United Nations and constitutional and human rights are being used, and could be used more effectively, to improve maternity services and to ensure access to drugs essential for reproductive health. Copyright © 2012 International Federation of Gynecology and Obstetrics. Published by Elsevier Ireland Ltd. All rights reserved.

  1. [Human factors and crisis resource management: improving patient safety].

    Science.gov (United States)

    Rall, M; Oberfrank, S

    2013-10-01

    A continuing high number of patients suffer harm from medical treatment. In 60-70% of the cases the sources of harm can be attributed to the field of human factors (HFs) and teamwork; nevertheless, those topics are still neither part of medical education nor of basic and advanced training even though it has been known for many years and it has meanwhile also been demonstrated for surgical specialties that training in human factors and teamwork considerably reduces surgical mortality.Besides the medical field, the concept of crisis resource management (CRM) has already proven its worth in many other industries by improving teamwork and reducing errors in the domain of human factors. One of the best ways to learn about CRM and HFs is realistic simulation team training with well-trained instructors in CRM and HF. The educational concept of the HOTT (hand over team training) courses for trauma room training offered by the DGU integrates these elements based on the current state of science. It is time to establish such training for all medical teams in emergency medicine and operative care. Accompanying safety measures, such as the development of a positive culture of safety in every department and the use of effective critical incident reporting systems (CIRs) should be pursued.

  2. Improving human object recognition performance using video enhancement techniques

    Science.gov (United States)

    Whitman, Lucy S.; Lewis, Colin; Oakley, John P.

    2004-12-01

    Atmospheric scattering causes significant degradation in the quality of video images, particularly when imaging over long distances. The principle problem is the reduction in contrast due to scattered light. It is known that when the scattering particles are not too large compared with the imaging wavelength (i.e. Mie scattering) then high spatial resolution information may be contained within a low-contrast image. Unfortunately this information is not easily perceived by a human observer, particularly when using a standard video monitor. A secondary problem is the difficulty of achieving a sharp focus since automatic focus techniques tend to fail in such conditions. Recently several commercial colour video processing systems have become available. These systems use various techniques to improve image quality in low contrast conditions whilst retaining colour content. These systems produce improvements in subjective image quality in some situations, particularly in conditions of haze and light fog. There is also some evidence that video enhancement leads to improved ATR performance when used as a pre-processing stage. Psychological literature indicates that low contrast levels generally lead to a reduction in the performance of human observers in carrying out simple visual tasks. The aim of this paper is to present the results of an empirical study on object recognition in adverse viewing conditions. The chosen visual task was vehicle number plate recognition at long ranges (500 m and beyond). Two different commercial video enhancement systems are evaluated using the same protocol. The results show an increase in effective range with some differences between the different enhancement systems.

  3. Improving Fleet and Industrial Supply Center, Sigonella, Italy: Detachment Bahrain’s Ship Maintenance Contracts in Southwest Asia

    Science.gov (United States)

    2011-05-16

    attention to managing our relationship with our customers . The lone success story in our relationships with our ship support repair activities is that...contracts • Limit competition • Poor quality of quotes/bids Process Improvements ) l h1 Customer  re ations ip  management ‐ Insist that sufficient time...Bulk funding/lack of proper controls/efficiency Process Improvements ) l h1 Customer  re ations ip  management ‐ Insist that sufficient time allocated to

  4. Predictive maintenance primer

    International Nuclear Information System (INIS)

    Flude, J.W.; Nicholas, J.R.

    1991-04-01

    This Predictive Maintenance Primer provides utility plant personnel with a single-source reference to predictive maintenance analysis methods and technologies used successfully by utilities and other industries. It is intended to be a ready reference to personnel considering starting, expanding or improving a predictive maintenance program. This Primer includes a discussion of various analysis methods and how they overlap and interrelate. Additionally, eighteen predictive maintenance technologies are discussed in sufficient detail for the user to evaluate the potential of each technology for specific applications. This document is designed to allow inclusion of additional technologies in the future. To gather the information necessary to create this initial Primer the Nuclear Maintenance Applications Center (NMAC) collected experience data from eighteen utilities plus other industry and government sources. NMAC also contacted equipment manufacturers for information pertaining to equipment utilization, maintenance, and technical specifications. The Primer includes a discussion of six methods used by analysts to study predictive maintenance data. These are: trend analysis; pattern recognition; correlation; test against limits or ranges; relative comparison data; and statistical process analysis. Following the analysis methods discussions are detailed descriptions for eighteen technologies analysts have found useful for predictive maintenance programs at power plants and other industrial facilities. Each technology subchapter has a description of the operating principles involved in the technology, a listing of plant equipment where the technology can be applied, and a general description of the monitoring equipment. Additionally, these descriptions include a discussion of results obtained from actual equipment users and preferred analysis techniques to be used on data obtained from the technology. 5 refs., 30 figs

  5. Modelling the Role of Human Resource Management in Continuous Improvement

    DEFF Research Database (Denmark)

    Jørgensen, Frances; Hyland, Paul; Kofoed, Lise B.

    2006-01-01

    Although it is widely acknowledged that both Human Resource Management (HRM) and Continuous Improvement have the potential to positively influencing organizational performance, very little attention has been given to how certain HRM practices may support CI, and consequently, a company...... developed by de Leede and Looise (2005) serve as the framework for examining how specific bundles of HRM practices utilized during different phases of the CI implementation process may contribute to sustained organizational performance and enhanced operational performance. The primary contribution...... of the paper is theoretical in nature, as the model developed provides a greater understanding of how HRM can contribute to CI; however, the model also has practical value in that it suggests important relationships between various HRM practices and the behaviors necessary for successful CI. The paper...

  6. Haptic Human-Human Interaction Through a Compliant Connection Does Not Improve Motor Learning in a Force Field

    NARCIS (Netherlands)

    Beckers, Niek; Keemink, Arvid; van Asseldonk, Edwin; van der Kooij, Herman; Prattichizzo, Domenico; Shinoda, Hiroyuki; Tan, Hong Z.; Ruffaldi, Emanuele; Frisoli, Antonio

    2018-01-01

    Humans have a natural ability to haptically interact with other humans, for instance during physically assisting a child to learn how to ride a bicycle. A recent study has shown that haptic human-human interaction can improve individual motor performance and motor learning rate while learning to

  7. Strategy to maximize maintenance operation

    OpenAIRE

    Espinoza, Michael

    2005-01-01

    This project presents a strategic analysis to maximize maintenance operations in Alcan Kitimat Works in British Columbia. The project studies the role of maintenance in improving its overall maintenance performance. It provides strategic alternatives and specific recommendations addressing Kitimat Works key strategic issues and problems. A comprehensive industry and competitive analysis identifies the industry structure and its competitive forces. In the mature aluminium industry, the bargain...

  8. Improving flight condition situational awareness through Human Centered Design.

    Science.gov (United States)

    Craig, Carol

    2012-01-01

    In aviation, there is currently a lack of accurate and timely situational information, specifically weather data, which is essential when dealing with the unpredictable complexities that can arise while flying. For example, weather conditions that require immediate evasive action by the flight crew, such as isolated heavy rain, micro bursts, and atmospheric turbulence, require that the flight crew receive near real-time and precise information about the type, position, and intensity of those conditions. Human factors issues arise in considering how to display the various sources of weather information to the users of that information and how to integrate this display into the existing environment. In designing weather information display systems, it is necessary to meet the demands of different users, which requires an examination of the way in which the users process and use weather information. Using Human Centered Design methodologies and concepts will result in a safer, more efficient and more intuitive solution. Specific goals of this approach include 1) Enabling better fuel planning; 2) Allowing better divert strategies; 3) Ensuring pilots, navigators, dispatchers and mission planners are referencing weather from the same sources; 4) Improving aircrew awareness of aviation hazards such as turbulence, icing, hail and convective activity; 5) Addressing inconsistent availability of hazard forecasts outside the United States Air Defense Identification Zone (ADIZ); and 6) Promoting goal driven approaches versus event driven (prediction).

  9. Protein supplements after weight loss do not improve weight maintenance compared with recommended dietary protein intake despite beneficial effects on appetite sensation and energy expenditure

    DEFF Research Database (Denmark)

    Kjølbæk, Louise; Sørensen, Lone Brinkmann; Søndertoft, Nadja Buus

    2017-01-01

    Background: High-protein diets increase weight loss (WL) during energy restriction; therefore, it has been suggested that additional protein intake may improve weight maintenance (WM) after WL.Objective: We investigated the effect of protein supplements from either whey with or without calcium...... were performed to investigate diet-induced-thermogenesis (DIT) and appetite sensation. Compliance was tested by 24-h urinary nitrogen excretion.Results: A total of 151 participants completed the WM period. The control and 3 protein supplements did not result in different mean ± SD weight regains (whey.......58 ± 1.4 kg; and control: 1.74 ± 1.4 kg; P = 0.50) during WM. Changes in blood pressure and blood biochemistry were not different between groups. Compared with the control, protein supplementation resulted in higher DIT (∼30 kJ/2.5 h) and resting energy expenditure (243 kJ/d) and an anorexigenic appetite...

  10. Behaviour change intervention to improve shared toilet maintenance and cleanliness in urban slums of Dhaka: a cluster-randomised controlled trial.

    Science.gov (United States)

    Alam, Mahbub-Ul; Winch, Peter J; Saxton, Ronald E; Nizame, Fosiul A; Yeasmin, Farzana; Norman, Guy; Masud, Abdullah-Al; Begum, Farzana; Rahman, Mahbubur; Hossain, Kamal; Layden, Anita; Unicomb, Leanne; Luby, Stephen P

    2017-08-01

    Shared toilets in urban slums are often unclean and poorly maintained, discouraging consistent use and thereby limiting impacts on health and quality of life. We developed behaviour change interventions to support shared toilet maintenance and improve user satisfaction. We report the intervention effectiveness on improving shared toilet cleanliness. We conducted a cluster-randomised controlled trial among users of 1226 shared toilets in 23 Dhaka slums. We assessed baseline toilet cleanliness in January 2015. The six-month intervention included provision of hardware (bin for solid waste, 4 l flushing bucket, 70 l water reservoir), and behaviour change communication (compound meetings, interpersonal household sessions, signs depicting rules for toilet use). We estimated the adjusted difference in difference (DID) to assess outcomes and accounted for clustering effects using generalised estimating equations. Compared to controls, intervention toilets were more likely to have water available inside toilet cubicles (DID: +4.7%, 95% CI: 0.2, 9.2), access to brush/broom for cleaning (DID: +8.4%, 95% CI: 2, 15) and waste bins (DID: +63%, 95% CI: 59, 66), while less likely to have visible faeces inside the pan (DID: -13%, 95% CI: -19, -5), the smell of faeces (DID: -7.6%, 95% CI: -14, -1.3) and household waste inside the cubicle (DID: -4%, 95% CI: -7, -1). In one of few efforts to promote shared toilet cleanliness, intervention compounds were significantly more likely to have cleaner toilets after six months. Future research might explore how residents can self-finance toilet maintenance, or employ mass media to reduce per-capita costs of behaviour change. © 2017 John Wiley & Sons Ltd.

  11. Mechanical stimulation improves tissue-engineered human skeletal muscle

    Science.gov (United States)

    Powell, Courtney A.; Smiley, Beth L.; Mills, John; Vandenburgh, Herman H.

    2002-01-01

    Human bioartificial muscles (HBAMs) are tissue engineered by suspending muscle cells in collagen/MATRIGEL, casting in a silicone mold containing end attachment sites, and allowing the cells to differentiate for 8 to 16 days. The resulting HBAMs are representative of skeletal muscle in that they contain parallel arrays of postmitotic myofibers; however, they differ in many other morphological characteristics. To engineer improved HBAMs, i.e., more in vivo-like, we developed Mechanical Cell Stimulator (MCS) hardware to apply in vivo-like forces directly to the engineered tissue. A sensitive force transducer attached to the HBAM measured real-time, internally generated, as well as externally applied, forces. The muscle cells generated increasing internal forces during formation which were inhibitable with a cytoskeleton depolymerizer. Repetitive stretch/relaxation for 8 days increased the HBAM elasticity two- to threefold, mean myofiber diameter 12%, and myofiber area percent 40%. This system allows engineering of improved skeletal muscle analogs as well as a nondestructive method to determine passive force and viscoelastic properties of the resulting tissue.

  12. Effectively Managing Nuclear Risk Through Human Performance Improvement

    International Nuclear Information System (INIS)

    Coe, Richard; Lake, Patricia

    2003-01-01

    The U.S. commercial nuclear industry has just completed an outstanding decade of plant performance. Safety levels and electric production are at unprecedented high levels and continue to exceed even high industry goals. Nuclear energy continues to keep the highest priority on performance improvement programs and highly trained and qualified people that maintain its record setting safety and reliability of operations. While the industry has maintained a high level of performance, the advent of deregulation and the consolidation of nuclear power plant ownership, as well as the current climate for concern about both rising energy costs and the availability of power, have raised the standard for nuclear energy's level of competitiveness in today's market place. The resulting challenge is how to more effectively manage risk and to improve performance even further in a generally high-performing industry. One of the most effective ways to develop this culture is to apply the principles of Hum an Performance Technology, or HPT. HPT is a relatively new field. Its principles are derived from the research and practice of behavioral and cognitive psychologists, instructional technologists, training designers, organizational developers, and various human resource specialists. Using the principles of HPT can help the nuclear industry successfully meet ever-changing environmental and business demands

  13. HMM Adaptation for Improving a Human Activity Recognition System

    Directory of Open Access Journals (Sweden)

    Rubén San-Segundo

    2016-09-01

    Full Text Available When developing a fully automatic system for evaluating motor activities performed by a person, it is necessary to segment and recognize the different activities in order to focus the analysis. This process must be carried out by a Human Activity Recognition (HAR system. This paper proposes a user adaptation technique for improving a HAR system based on Hidden Markov Models (HMMs. This system segments and recognizes six different physical activities (walking, walking upstairs, walking downstairs, sitting, standing and lying down using inertial signals from a smartphone. The system is composed of a feature extractor for obtaining the most relevant characteristics from the inertial signals, a module for training the six HMMs (one per activity, and the last module for segmenting new activity sequences using these models. The user adaptation technique consists of a Maximum A Posteriori (MAP approach that adapts the activity HMMs to the user, using some activity examples from this specific user. The main results on a public dataset have reported a significant relative error rate reduction of more than 30%. In conclusion, adapting a HAR system to the user who is performing the physical activities provides significant improvement in the system’s performance.

  14. Financial incentives to improve adherence to antipsychotic maintenance medication in non-adherent patients: a cluster randomised controlled trial.

    Science.gov (United States)

    Priebe, Stefan; Bremner, Stephen A; Lauber, Christoph; Henderson, Catherine; Burns, Tom

    2016-09-01

    Poor adherence to long-term antipsychotic injectable (LAI) medication in patients with psychotic disorders is associated with a range of negative outcomes. No psychosocial intervention has been found to be consistently effective in improving adherence. To test whether or not offering financial incentives is effective and cost-effective in improving adherence and to explore patient and clinician experiences with such incentives. A cluster randomised controlled trial with economic and nested qualitative evaluation. The intervention period lasted for 12 months with 24 months' follow-up. The unit of randomisation was mental health teams in the community. Community teams in secondary mental health care. Patients with a diagnosis of schizophrenia, schizoaffective psychosis or bipolar illness, receiving ≤ 75% of their prescribed LAI medication. In total, 73 teams with 141 patients (intervention n = 78 and control n = 63) were included. Participants in the intervention group received £15 for each LAI medication. Patients in the control group received treatment as usual. adherence to LAI medication (the percentage of received out of those prescribed). percentage of patients with at least 95% adherence; clinical global improvement; subjective quality of life; satisfaction with medication; hospitalisation; adverse events; and costs. Qualitative evaluation: semistructured interviews with patients in the intervention group and their clinicians. outcome data were available for 131 patients. Baseline adherence was 69% in the intervention group and 67% in the control group. During the intervention period, adherence was significantly higher in the intervention group than in the control group (85% vs. 71%) [adjusted mean difference 11.5%, 95% confidence interval (CI) 3.9% to 19.0%; p = 0.003]. Secondary outcome: patients in the intervention group showed statistically significant improvement in adherence of at least 95% (adjusted odds ratio 8.21, 95% CI 2.00 to 33

  15. Proceedings of the fourth international conference on CANDU maintenance

    International Nuclear Information System (INIS)

    1997-01-01

    These proceedings record the information presented at the 4th International Conference on CANDU Maintenance held November 16-18,1997 in Toronto, Canada. The papers for these proceedings were prepared on component maintenance, human performance, steam generator leak detection, fuel channel inspections, rotating equipment maintenance, surveillance programs, inspection techniques, valve maintenance, steam generator repairs and performance, reactor aging management and preventative maintenance

  16. Proceedings of the fourth international conference on CANDU maintenance

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1997-07-01

    These proceedings record the information presented at the 4th International Conference on CANDU Maintenance held November 16-18,1997 in Toronto, Canada. The papers for these proceedings were prepared on component maintenance, human performance, steam generator leak detection, fuel channel inspections, rotating equipment maintenance, surveillance programs, inspection techniques, valve maintenance, steam generator repairs and performance, reactor aging management and preventative maintenance.

  17. Training of maintenance personnel

    International Nuclear Information System (INIS)

    Rabouhams, J.

    1986-01-01

    This lecture precises the method and means developed by EDF to ensure the training of maintenance personnel according to their initial educational background and their experience. The following points are treated: General organization of the training for maintenance personnel in PWR and GCR nuclear power stations and in Creys Malville fast breeder reactor; Basic nuclear training and pedagogical aids developed for this purpose; Specific training and training provided by contractors; complementary training taking into account the operation experience and feedback; Improvement of velocity, competence and safety during shut-down operations by adapted training. (orig.)

  18. Importance of Lean Muscle Maintenance to Improve Insulin Resistance by Body Weight Reduction in Female Patients with Obesity.

    Science.gov (United States)

    Fukushima, Yaeko; Kurose, Satoshi; Shinno, Hiromi; Cao Thu, Ha; Takao, Nana; Tsutsumi, Hiromi; Kimura, Yutaka

    2016-04-01

    It has recently been suggested that skeletal muscle has an important role in insulin resistance in obesity, in addition to exercise tolerance and the fat index. The aim of this study was to identify body composition factors that contribute to improvement of insulin resistance in female patients with obesity who reduce body weight. We studied 92 female obese patients (age 40.9±10.4 years, body mass index 33.2±4.6 kg/m²) who reduced body weight by ≥5% after an intervention program including diet, exercise therapy, and cognitive behavioral therapy. Before and after the intervention, body composition was evaluated by dual-energy X-ray absorptiometry to examine changes in skeletal muscle mass. Homeostasis model assessment of insulin resistance (HOMA-IR) was measured as an index of insulin resistance. Cardiopulmonary exercise was also performed by all patients. There were significant improvements in body weight (-10.3%±4.5%), exercise tolerance (anaerobic threshold oxygen uptake 9.1%±18.4%, peak oxygen uptake 11.0%±14.2%), and HOMA-IR (-20.2%±38.3%). Regarding body composition, there were significant decreases in total body fat (-19.3%±9.6%), total fat-free mass (-2.7%±4.3%), and % body fat (-10.1%±7.5%), whereas % skeletal muscle significantly increased (8.9%±7.2%). In stepwise multiple linear regression analysis with change in HOMA-IR as the dependent variable, the change in % skeletal muscle was identified as an independent predictor (β=-0.280, R²=0.068, Pmaintenance of skeletal muscle mass.

  19. Development of plant maintenance systems

    International Nuclear Information System (INIS)

    Tomita, Jinji; Ike, Masae; Nakayama, Kenji; Kato, Hisatomo

    1989-01-01

    Toshiba is making active efforts for the continuing improvement of reliability and maintainability of operating nuclear power plants. As a part of these efforts, the company has developed new maintenance administration systems, diagnostic monitoring facilities for plant equipments, computer-aided expert systems, and remote-controlled machines for maintenance work. The maintenance administration systems provide efficient work plans and data acquisition capabilities for the management of personnel and equipments involved in nuclear power plant maintenance. The plant diagnostic facilities monitor and diagnose plant conditions for preventive maintenance, as well as enabling rapid countermeasures to be carried out should they be required. Expert systems utilizing artificial intelligence (AI) technology are also employed. The newly developed remote-controlled machines are useful tools for the maintenance inspection of equipment which can not be easily accessed. (author)

  20. PORTFOLIO OF POTENTIAL STRATEGIES IN AERONAUTIC MAINTENANCE

    International Nuclear Information System (INIS)

    Rolet, S.

    2010-01-01

    EADS divisions aim more and more at developing services associated to their platforms. EADS divisions, like Airbus and Eurocopter, are investigating on services associated to their platforms in order to add them value. One possible service consists in structural maintenance operation assistance, especially for NDT operations performed by the customer. EADS Innovation Works envisages three different and complementary enhanced structural maintenance categories. Enhanced NDT improves standard NDT operation environment. This is made possible by the existence of 'smart' NDT tools that are computer based and therefore able to support other functions. These functions range from local smart data processing and display to remote expert assisted operation. Passive Sensor Network relies on sensors permanently installed on aircraft structure. Interrogation of sensors is performed on ground and off line (while structure is not loaded except by its own weight). It can be done at arbitrary times in order to determine structure health. The aim is to give easy access to some hidden ''hot spots,'' to reduce human factor in structure health assessment and optimize maintenance. Structural Health Monitoring goes a step beyond Passive Sensor Network, because interrogation units are on board the aircraft and may be connected to aircraft network. It allows to use on-line techniques such as adapted acoustic emission and to automatically raise an alarm when a defect appears in the structure. This paper presents these different ways of improving structural maintenance operations in service, with their respective advantages and limitations.

  1. Reliability Centered Maintenance - Methodologies

    Science.gov (United States)

    Kammerer, Catherine C.

    2009-01-01

    Journal article about Reliability Centered Maintenance (RCM) methodologies used by United Space Alliance, LLC (USA) in support of the Space Shuttle Program at Kennedy Space Center. The USA Reliability Centered Maintenance program differs from traditional RCM programs because various methodologies are utilized to take advantage of their respective strengths for each application. Based on operational experience, USA has customized the traditional RCM methodology into a streamlined lean logic path and has implemented the use of statistical tools to drive the process. USA RCM has integrated many of the L6S tools into both RCM methodologies. The tools utilized in the Measure, Analyze, and Improve phases of a Lean Six Sigma project lend themselves to application in the RCM process. All USA RCM methodologies meet the requirements defined in SAE JA 1011, Evaluation Criteria for Reliability-Centered Maintenance (RCM) Processes. The proposed article explores these methodologies.

  2. Generation, isolation, and maintenance of human mast cells and mast cell lines derived from peripheral blood or cord blood

    DEFF Research Database (Denmark)

    Rådinger, Madeleine; Jensen, Bettina M; Kuehn, Hye Sun

    2010-01-01

    Antigen-mediated mast cell activation is a pivotal step in the initiation of allergic disorders including anaphylaxis and atopy. To date, studies aimed at investigating the mechanisms regulating these responses, and studies designed to identify potential ways to prevent them, have primarily been...... conducted in rodent mast cells. However, to understand how these responses pertain to human disease, and to investigate and develop novel therapies for the treatment of human mast cell-driven disease, human mast cell models may have greater relevance. Recently, a number of systems have been developed...... to allow investigators to readily obtain sufficient quantities of human mast cells to conduct these studies. These mast cells release the appropriate suite of inflammatory mediators in response to known mast cell activators including antigen. These systems have also been employed to examine the signaling...

  3. Maintenance for life management

    International Nuclear Information System (INIS)

    Hevia, F.

    1997-01-01

    Life Management is based on the detection, monitoring and control of long-term degradation that affects individual plant components and important populations. Experience has shown that in many cases current maintenance practices do not attend to ageing directly; instead they deal with the consequences when it is already too late, when good Life Management is no longer practical. This has brought about the need for specific Maintenance Evaluation and Improvement Programmes to adjust to the basic objective of Life Management which is to project against, monitor and mitigate ageing that can affect the safe and profitable operating life of the facility. New regulatory requirements for ageing monitoring and effective maintenance to ensure safety (Maintenance Rule) have made it even more necessary to implement the Maintenance Evaluation Programme to cope with ageing, and to integrate that tasks in both programmes to optimise effort and use of tools. This paper presents a brief description of the objectives and methodologies of these Programmes which has been applied to plants around the world and in Spain at the Garona and Vandellos II plants in Spain as part of the PIE project for developing a Remanent Life Evaluation System for nuclear power plants. (Author)

  4. Opportune maintenance and predictive maintenance decision support

    OpenAIRE

    Thomas , Edouard; Levrat , Eric; Iung , Benoît; Cocheteux , Pierre

    2009-01-01

    International audience; Conventional maintenance strategies on a single component are being phased out in favour of more predictive maintenance actions. These new kinds of actions are performed in order to control the global performances of the whole industrial system. They are anticipative in nature, which allows a maintenance expert to consider non-already-planned maintenance actions. Two questions naturally emerge: when to perform a predictive maintenance action; how a maintenance expert c...

  5. CANDU plant maintenance: Recent developments

    International Nuclear Information System (INIS)

    Charlebois, P.

    2000-01-01

    CANDU units have long been recognized for their exceptional safety and reliability. Continuing development in the maintenance area has played a key role in achieving this performance level. For over two decades, safety system availability has been monitored closely and system maintenance programs adjusted accordingly to maintain high levels of performance. But as the plants approach mid life in a more competitive environment and component aging becomes a concern, new methods and techniques are necessary. As a result, recent developments are moving the maintenance program largely from a corrective and preventive approach to predictive and condition based maintenance. The application of these techniques is also being extended to safety related systems. These recent developments include use of reliability centred methods to define system maintenance requirements and strategies. This approach has been implemented on a number of systems at Canadian CANDU plants with positive results. The pilot projects demonstrated that the overall maintenance effort remained relatively constant while the system performance improved. It was also possible to schedule some of the redundant component maintenance during plant operation without adverse impact on system availability. The probabilistic safety assessment was found to be useful in determining the safety implications of component outages. These new maintenance strategies are now making use of predictive and condition based maintenance techniques to anticipate equipment breakdown and schedule preventive maintenance as the need arises rather than time based. Some of these techniques include valve diagnostics, vibration monitoring, oil analysis, thermography. Of course, these tools and techniques must form part of an overall maintenance management system to ensure that maintenance becomes a living program. To facilitate this process and contain costs, new information technology tools are being introduced to provide system engineers

  6. Communication of Robot Status to Improve Human-Robot Collaboration

    Data.gov (United States)

    National Aeronautics and Space Administration — Future space exploration will require humans and robots to collaborate to perform all the necessary tasks. Current robots mostly operate separately from humans due...

  7. Maintenance management for nuclear power plant 'Integrated valve maintenance'

    International Nuclear Information System (INIS)

    Gerner, P.; Zanner, G.

    2001-01-01

    The deregulation of Europe's power market does force many utilities, and especially nuclear power plant operators, to introduce extensive cost-cutting measures in order to be able to compete within this new environment. The optimization of plant outages provides considerable potential for raising plant availability but can also lower operating costs by reducing e.g. expenditure on maintenance. Siemens Nuclear Power GmbH, in cooperation with plant operators, is currently implementing new and improved service concepts which can have a major effect on the way in which maintenance will be performed in the future. Innovative service packages for maintenance in nuclear power plants are available which can be used to perform a time- and cost-effective maintenance. The concepts encompass optimization of the overall sequence from planning in advance to the individual measures including reduction of the scope of maintenance activities, identification of cost cutting potential and bundling of maintenance activities. The main features of these maintenance activities are illustrated here using the examples of outage planning and integrated valve maintenance. In nuclear power plants approx. 5000 valves are periodically preventively, condition-based or breakdown-based maintained. Because of this large number of valves to be maintained a high potential of improvements and cost reductions can be achieved by performing an optimized, cost-effective maintenance based on innovative methods and tools. Siemens Nuclear Power GmbH has developed and qualified such tools which allow to reduce service costs while maintaining high standards of safety and availability. By changing from preventive to predictive (condition-based) maintenance - the number of valves to be maintained may be reduced considerably. The predictive maintenance is based on the Siemens Nuclear Power GmbH diagnostic and evaluation method (ADAM). ADAM is used to monitor the operability of valves by analytical verification of

  8. Application of Dr. Mainte, integrated simulator of maintenance optimization, to LWRs

    International Nuclear Information System (INIS)

    Isobe, Yoshihiro; Sagisaka, Mitsuyuki; Etoh, Junji; Matsunaga, Takashi; Kosaka, Toru; Matsumoto, Satoshi; Yoshimura, Shinobu

    2015-01-01

    Dr. Mainte, an integrated simulator for maintenance optimization of LWRs (Light Water Reactors) is based on PFM (Probabilistic Fracture Mechanics) analyses. The concept of the simulator is to provide a decision-making system to optimize maintenance activities for typical components and piping systems in nuclear power plants totally and quantitatively in terms of safety, availability, economic rationality, environmental impact and social acceptance. For the further improvement of the safety and availability of nuclear power plants, the effect of human error and its reduction on the optimization of maintenance activities have been studied. In addition, an approach of reducing human error is proposed. (author)

  9. Anaplasma phagocytophilum inhibits human neutrophil apoptosis via upregulation of bfl-1, maintenance of mitochondrial membrane potential and prevention of caspase 3 activation.

    Science.gov (United States)

    Ge, Yan; Yoshiie, Kiyotaka; Kuribayashi, Futoshi; Lin, Mingqun; Rikihisa, Yasuko

    2005-01-01

    The inhibition of neutrophil apoptosis plays a central role in human granulocytic anaplasmosis. Intracellular signalling pathways through which the obligatory intracellular bacterium Anaplasma phagocytophilum inhibits the spontaneous apoptosis of human peripheral blood neutrophils were investigated. bfl-1 mRNA levels in uninfected neutrophils after 12 h in culture were reduced to approximately 5-25% of 0 h levels, but remained high in infected neutrophils. The eukaryotic RNA synthesis inhibitor, actinomycin D, prevented the maintenance of bfl-1 mRNA levels by A. phagocytophilum. Differences in mcl-1, bax, bcl-w, bad or bak mRNA levels in infected versus uninfected neutrophils were not remarkable. By using mitochondrial fluorescent dyes, Mitotracker Red and JC-1, it was found that most uninfected neutrophils lost mitochondrial membrane potential after 10-12 h incubation, whereas A. phagocytophilum-infected neutrophils maintained high membrane potential. Caspase 3 activity and the degree of apoptosis were lower in dose-dependent manner in A. phagocytophilum-infected neutrophils at 16 h post infection, as compared to uninfected neutrophils. Anti-active caspase 3 antibody labelling showed less positively stained population in infected neutrophils compared to those in uninfected neutrophils after 12 h incubation. These results suggest that A. phagocytophilum inhibits human neutrophil apoptosis via transcriptional upregulation of bfl-1 and inhibition of mitochondria-mediated activation of caspase 3.

  10. Maintenance of drug metabolism and transport functions in human precision-cut liver slices during prolonged incubation for 5 days

    NARCIS (Netherlands)

    Starokozhko, Viktoriia; Vatakuti, Suresh; Schievink, Bauke; Merema, Marjolijn T.; Asplund, Annika; Synnergren, Jane; Aspegren, Anders; Groothuis, Geny M. M.

    Human precision-cut liver slices (hPCLS) are a valuable ex vivo model that can be used in acute toxicity studies. However, a rapid decline in metabolic enzyme activity limits their use in studies that require a prolonged xenobiotic exposure. The aim of the study was to extend the viability and

  11. Programme evaluation: Can it improve human resource management practice?

    Directory of Open Access Journals (Sweden)

    Johann Louw

    2012-07-01

    Full Text Available Orientation: This is the final article in the special edition on human resource (HR programmes and evaluation. Its starting point is that programme evaluation is the application of a wide range of social science research methods that provide credible information about the need, use, planning, effectiveness and cost of a programme. Research purpose: The purpose of this article is to review the other articles in this volume, and to draw out general conclusions about their contributions to knowledge in the field. Motivation for the study: If evaluations are undertaken in the HR domain in South Africa, they remain mostly unpublished, and thus cannot contribute to a knowledge base for the field. Research design, approach and method: This article provides a theory-based approach to programme evaluation. The seven articles were analysed in terms of two major functions of programme evaluation, namely to ask ‘How does a programme work?’, and ‘Does it work?‘ Main findings: Eight overarching themes are identified in the articles included in this volume. Practical/managerial implications: The evidence discussed here can be used to make better decisions, promote organisational learning, improve practice, and enhance employee wellbeing. Contribution/value-add: The main contribution of this concluding article is its argument that research and theory in this field can enhance the work of HR professionals, by providing evidence about how ‘good’ a programme is, and why it is good. This adds substantial value in a world characterised by accountability and evidence-based practice.

  12. Simulated maintenance a virtual reality

    International Nuclear Information System (INIS)

    Lirvall, P.

    1995-01-01

    The article describes potential applications of personal computer-based virtual reality software. The applications are being investigated by Atomic Energy of Canada Limited's (AECL) Chalk River Laboratories for the Canadian deuterium-uranium (Candu) reactor. Objectives include: (1) reduction of outage duration and improved safety, (2) cost-effective and safe maintenance of equipment, (3) reduction of exposure times and identification of overexposure situations, (4) cost-effective training in a virtual control room simulator, (5) human factors evaluation of design interface, and (6) visualization of conceptual and detailed designs of critical nuclear field environments. A demonstration model of a typical reactor control room, the use of virtual reality in outage planning, and safety issues are outlined

  13. Optimizing preventive maintenance with maintenance templates

    International Nuclear Information System (INIS)

    Dozier, I.J.

    1996-01-01

    Rising operating costs has caused maintenance professionals to rethink their strategy for preventive maintenance (PM) programs. Maintenance Templates are pre-engineered PM task recommendations for a component type based on application of the component. Development of the maintenance template considers the dominant failure cause of the component and the type of preventive maintenance that can predict or prevent the failure from occurring. Maintenance template development also attempts to replace fixed frequency tasks with condition monitoring tasks such as vibration analysis or thermography. For those components that have fixed frequency PM intervals, consideration is given to the maintenance drivers such as criticality, environment and usage. This helps to maximize the PM frequency intervals and maximize the component availability. Maintenance Templates have been used at PECO Energy's Limerick Generating Station during the Reliability Centered Maintenance (RCM) Process to optimize their PM program. This paper describes the development and uses of the maintenance templates

  14. Gap Balancing Sacrifices Joint-Line Maintenance to Improve Gap Symmetry: 5-Year Follow-Up of a Randomized Controlled Trial.

    Science.gov (United States)

    Babazadeh, Sina; Dowsey, Michelle M; Vasimalla, Michael G; Stoney, James D; Choong, Peter F M

    2018-01-01

    Gap balancing (GB) has been noted to sacrifice joint-line maintenance to improve gap symmetry. This study aims to determine whether this change affects function or quality of life in the midterm. A prospective blinded randomized controlled trial was completed with 103 patients randomized to measured resection (n = 52) or GB (n = 51). Primary outcome measured was femoral component rotation. Secondary outcomes measured were joint-line change, gap symmetry, and function and quality-of-life outcomes. At 5 years, 83 of 103 patients (85%) were assessed. There was no significant difference between groups in terms of functional or quality of life outcomes. A subgroup analysis revealed that there was no significant association between those with asymmetrical flexion and/or extension or medial and/or lateral gaps during knee replacement and subsequent functional outcomes. No significant difference was detected with those with an elevated joint line and postoperative function. In the midterm, the resultant change in joint-line and maintained gap symmetry noted with GB does not result in significant change to function or quality of life. Copyright © 2017 Elsevier Inc. All rights reserved.

  15. A Revised Guide for Improving Teacher Education in Human Rights.

    Science.gov (United States)

    Phi Delta Kappa, Bloomington, IN. Commission of Education, Human Rights, and Responsibilities.

    This document serves as a guide for teacher education institutions and programs designed to prepare educators for meeting their responsibilities in the area of human rights and human relations. This second edition of the guide represents a substantial modification of the original guide, and includes many activities, experiences, and suggestions…

  16. A passive heat maintenance strategy implemented during a simulated half-time improves lower body power output and repeated sprint ability in professional Rugby Union players.

    Directory of Open Access Journals (Sweden)

    Mark Russell

    Full Text Available Reduced physical performance has been observed following the half-time period in team sports players, likely due to a decrease in muscle temperature during this period. We examined the effects of a passive heat maintenance strategy employed between successive exercise bouts on core temperature (Tcore and subsequent exercise performance. Eighteen professional Rugby Union players completed this randomised and counter-balanced study. After a standardised warm-up (WU and 15 min of rest, players completed a repeated sprint test (RSSA 1 and countermovement jumps (CMJ. Thereafter, in normal training attire (Control or a survival jacket (Passive, players rested for a further 15 min (simulating a typical half-time before performing a second RSSA (RSSA 2 and CMJ's. Measurements of Tcore were taken at baseline, post-WU, pre-RSSA 1, post-RSSA 1 and pre-RSSA 2. Peak power output (PPO and repeated sprint ability was assessed before and after the simulated half-time. Similar Tcore responses were observed between conditions at baseline (Control: 37.06±0.05°C; Passive: 37.03±0.05°C and for all other Tcore measurements taken before half-time. After the simulated half-time, the decline in Tcore was lower (-0.74±0.08% vs. -1.54±0.06%, p<0.001 and PPO was higher (5610±105 W vs. 5440±105 W, p<0.001 in the Passive versus Control condition. The decline in PPO over half-time was related to the decline in Tcore (r = 0.632, p = 0.005. In RSSA 2, best, mean and total sprint times were 1.39±0.17% (p<0.001, 0.55±0.06% (p<0.001 and 0.55±0.06% (p<0.001 faster for Passive versus Control. Passive heat maintenance reduced declines in Tcore that were observed during a simulated half-time period and improved subsequent PPO and repeated sprint ability in professional Rugby Union players.

  17. A new theoretical approach to the functional meaning of sleep and dreaming in humans based on the maintenance of 'predictive psychic homeostasis'.

    Science.gov (United States)

    Agnati, Luigi F; Barlow, Peter W; Baluška, František; Tonin, Paolo; Guescini, Michele; Leo, Giuseppina; Fuxe, Kjell

    2011-11-01

    Different theories have been put forward during the last decade to explain the functional meaning of sleep and dreaming in humans. In the present paper, a new theory is presented which, while taking advantage of these earlier theories, introduces the following new and original aspects:   • Circadian rhythms relevant to various organs of the body affect the reciprocal interactions which operate to maintain constancy of the internal milieu and thereby also affect the sleep/wakefulness cycle. Particular attention is given to the constancy of natraemia and osmolarity and to the permissive role that the evolution of renal function has had for the evolution of the central nervous system and its integrative actions. • The resetting of neuro-endocrine controls at the onset of wakefulness leads to the acquisition of new information and its integration within previously stored memories. This point is dealt with in relation to Moore-Ede's proposal for the existence of a 'predictive homeostasis'. • The concept of 'psychic homeostasis' is introduced and is considered as one of the most important states since it is aimed at the well-being, or eudemonia, of the human psyche. Sleep and dreaming in humans are discussed as important functions for the maintenance of a newly proposed composite state: that of 'predictive psychic homeostasis'. On the basis of these assumptions, and in accordance with the available neurobiological data, the present paper puts forward the novel hypothesis that sleep and dreaming play important functions in humans by compensating for psychic allostatic overloads. Hence, both consolatory dreams and disturbing nightmares can be part of the vis medicatrix naturae, the natural healing power, in this case, the state of eudemonia.

  18. The long-term use of soap does not affect the pH-maintenance mechanism of human skin.

    Science.gov (United States)

    Takagi, Y; Kaneda, K; Miyaki, M; Matsuo, K; Kawada, H; Hosokawa, H

    2015-05-01

    The pH at the surface of healthy human skin is around 5. Cleansing the skin with soap increases the pH of the skin, which then returns to a more acidic pH within a few hours. However, the effects of skin cleansing with soap over a long time on the pH regulatory system is still unclear. We compared the pH of the skin between users of a soap-based cleanser and of a mild-acidic cleanser prior to and following the cleansing. This study had two groups of subjects, one group who had used a soap-based cleanser for more than 5 years and the other group who had used a mild-acidic cleanser for more than 5 years. The pH on the inner forearm of each subject was measured prior to and for 6 h after cleansing with a soap bar. There were no differences between the pH of the skin these two groups prior to cleansing, immediately after cleansing or in the pH recovery rate for 6 h. These results suggest that long-term continuous use of a soap-based cleanser does not affect the pH-maintaining mechanism of human skin. © 2014 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

  19. Maintenance in sustainable manufacturing

    Directory of Open Access Journals (Sweden)

    Vladimir Stuchly

    2014-09-01

    Full Text Available Background: Sustainable development is about reaching a balance between economic, social, and environmental goals, as well as people's participation in the planning process in order to gain their input and support. For a company, sustainable development means adoption of such business strategy and actions that contribute to satisfying present needs of company and stakeholders, as well as simultaneous protection, maintenance and strengthening of human and environmental potential which will be needed in the future. This new approach forces manufacturing companies to change their previous management paradigms. New management paradigm should include new issues and develop innovative methods, practices and technologies striving for solving problem of shortages of resources, softening environment overload and enabling development of environment-friendly lifecycle of products. Hence, its realization requires updating existing production models as they are based on previously accepted paradigm of unlimited resources and unlimited regeneration capabilities. Maintenance plays a crucial role because of its impact on availability, reliability, quality and life cycle cost, thus it should be one of the main pillars of new business running model.  Material and methods: The following paper is a result of research on the literature and observation of practices undertaken by a company within maintenance area. Results and conclusions: The main message is that considering sustainable manufacturing requires considerable expanding range of analysis and focusing on supporting processes. Maintenance offers numerous opportunities of decreasing influence of business processes on natural environment and more efficient resources utilization. The goal of maintenance processes realizing sustainable development strategy is increased profitability of exploitation and optimization of total lifecycle cost without disturbing safety and environmental issues. 

  20. Improved methods for reprogramming human dermal fibroblasts using fluorescence activated cell sorting.

    Directory of Open Access Journals (Sweden)

    David J Kahler

    Full Text Available Current methods to derive induced pluripotent stem cell (iPSC lines from human dermal fibroblasts by viral infection rely on expensive and lengthy protocols. One major factor contributing to the time required to derive lines is the ability of researchers to identify fully reprogrammed unique candidate clones from a mixed cell population containing transformed or partially reprogrammed cells and fibroblasts at an early time point post infection. Failure to select high quality colonies early in the derivation process results in cell lines that require increased maintenance and unreliable experimental outcomes. Here, we describe an improved method for the derivation of iPSC lines using fluorescence activated cell sorting (FACS to isolate single cells expressing the cell surface marker signature CD13(NEGSSEA4(POSTra-1-60(POS on day 7-10 after infection. This technique prospectively isolates fully reprogrammed iPSCs, and depletes both parental and "contaminating" partially reprogrammed fibroblasts, thereby substantially reducing the time and reagents required to generate iPSC lines without the use of defined small molecule cocktails. FACS derived iPSC lines express common markers of pluripotency, and possess spontaneous differentiation potential in vitro and in vivo. To demonstrate the suitability of FACS for high-throughput iPSC generation, we derived 228 individual iPSC lines using either integrating (retroviral or non- integrating (Sendai virus reprogramming vectors and performed extensive characterization on a subset of those lines. The iPSC lines used in this study were derived from 76 unique samples from a variety of tissue sources, including fresh or frozen fibroblasts generated from biopsies harvested from healthy or disease patients.

  1. Innovative strategies to improve human resources for health in Africa ...

    African Journals Online (AJOL)

    and scaling up health professionals' education and training, calling for sustainable and ... SA faces similar human resource challenges to other African countries. ... It also supports teacher ... as opposed to the traditional didactic-only lectures.

  2. Human Factors Guidance for Control Room and Digital Human-System Interface Design and Modification, Guidelines for Planning, Specification, Design, Licensing, Implementation, Training, Operation and Maintenance

    Energy Technology Data Exchange (ETDEWEB)

    R. Fink, D. Hill, J. O' Hara

    2004-11-30

    Nuclear plant operators face a significant challenge designing and modifying control rooms. This report provides guidance on planning, designing, implementing and operating modernized control rooms and digital human-system interfaces.

  3. Human Factors Guidance for Control Room and Digital Human-System Interface Design and Modification. Guidelines for Planning, Specification, Design, Licensing, Implementation, Training, Operation and Maintenance

    International Nuclear Information System (INIS)

    Fink, R.; Hill, D.; O'Hara, J.

    2004-01-01

    Nuclear plant operators face a significant challenge designing and modifying control rooms. This report provides guidance on planning, designing, implementing and operating modernized control rooms and digital human-system interfaces

  4. Kynurenine Pathway Metabolism is Involved in the Maintenance of the Intracellular NAD Concentration in Human Primary Astrocytes

    Directory of Open Access Journals (Sweden)

    Ross Grant

    2010-01-01

    Full Text Available Efficient synthesis of NAD + is critical to maintaining cell viability in all organs of the body. However, little is known of the pathway(s by which cells of the central nervous system produce NAD + . The aim of this study was to investigate the relationship, between tryptophan degradation via the kynurenine pathway (KP and de novo NAD + synthesis in human astrocytes, a major cell type within the brain. In this study we observed that inhibition of single enzymes of the KP resulted in significant decreases in NAD + levels in astroglial cells after a 24 hr period. We also observed that astrocytes cultured in media deficient in tryptophan, nicotinic acid and nicotinamide resulted in a 50% decrease in NAD + levels after 24 hrs. This decrease in NAD + was partially restored by supplementation of the culture media with either tryptophan or kynurenine, or nicotinic acid or with supply of the salvage pathway precursor nicotinamide.

  5. Kynurenine Pathway Metabolism is Involved in the Maintenance of the Intracellular NAD+ Concentration in Human Primary Astrocytes

    Science.gov (United States)

    Grant, Ross; Nguyen, Susan; Guillemin, Gilles

    2010-01-01

    Efficient synthesis of NAD+ is critical to maintaining cell viability in all organs of the body. However, little is known of the pathway(s) by which cells of the central nervous system produce NAD+. The aim of this study was to investigate the relationship, between tryptophan degradation via the kynurenine pathway (KP) and de novo NAD+ synthesis in human astrocytes, a major cell type within the brain. In this study we observed that inhibition of single enzymes of the KP resulted in significant decreases in NAD+ levels in astroglial cells after a 24 hr period. We also observed that astrocytes cultured in media deficient in tryptophan, nicotinic acid and nicotinamide resulted in a 50% decrease in NAD+ levels after 24 hrs. This decrease in NAD+ was partially restored by supplementation of the culture media with either tryptophan or kynurenine, or nicotinic acid or with supply of the salvage pathway precursor nicotinamide. PMID:22084595

  6. Development of a daily maintenance work management system for nuclear power plants

    International Nuclear Information System (INIS)

    Yoshimura, Sadanori; Maita, Keikichi; Ogawa, Koutaro; Tabata, Nobuyuki; Shibuya, Shinya

    1999-01-01

    Maintenance work plays an important role in keeping the safety and reliability of nuclear power plants. Especially, with the recent trends of reducing the outage length, safe and reliable execution of maintenance work is more earnestly required than ever. Taking this situation into account, a daily maintenance work management system has been developed to support the execution of maintenance work for nuclear power plants. This system supports maintenance personnel in writing and approving the daily work instruction sheet and reduces their workload by providing predetermined lists of items necessary for filling up the sheet and by applying an electronic approval procedure. It also provides information through a computer network to improve the communication among maintenance personnel. For work steps to be treated in the daily work instruction sheet, an analysis was made to identify potential human errors and related counter measures, which were then linked to safety and quality assurance instructions of the sheet. Based on this information, the system automatically presents the safety and quality assurance instructions related to the work content listed in the sheet to improve the appropriateness of the instructions. A prototype of the daily maintenance work management system was developed and a trial use was made for actual periodic maintenance work at a nuclear power plant. This experience shows the usefulness of the system in reducing the workload of maintenance personnel and in providing safer work instructions. (author)

  7. My4Sight: A Human Computation Platform for Improving Flu Predictions

    OpenAIRE

    Akupatni, Vivek Bharath

    2015-01-01

    While many human computation (human-in-the-loop) systems exist in the field of Artificial Intelligence (AI) to solve problems that can't be solved by computers alone, comparatively fewer platforms exist for collecting human knowledge, and evaluation of various techniques for harnessing human insights in improving forecasting models for infectious diseases, such as Influenza and Ebola. In this thesis, we present the design and implementation of My4Sight, a human computation system develope...

  8. Florida maintenance rating program (MRP) assessment and enhancement : final report, May 28, 2008.

    Science.gov (United States)

    2008-05-28

    The Maintenance Rating Program (MRP), developed in 1985 by FDOT, is a statewide maintenance system aimed : at evaluating the State highway maintenance conditions, and determining FDOT asset maintenance needs. In the : quest for continuous improvement...

  9. Glucocorticoids improve high-intensity exercise performance in humans

    DEFF Research Database (Denmark)

    Casuso, Rafael A; Melskens, Lars; Bruhn, Thomas

    2014-01-01

    It was investigated whether oral dexamethasone (DEX) administration improves exercise performance by reducing the initial rate of muscle fatigue development during dynamic exercise.......It was investigated whether oral dexamethasone (DEX) administration improves exercise performance by reducing the initial rate of muscle fatigue development during dynamic exercise....

  10. Tribulus terrestris Extract Improves Human Sperm Parameters In Vitro

    Science.gov (United States)

    Khaleghi, Sara; Bakhtiari, Mitra; Asadmobini, Atefeh; Esmaeili, Farzane

    2016-01-01

    Objective. The object of present study was to investigate the effects of direct addition of Tribulus terrestris extract on human sperm parameters. Design. Semen specimens from 40 healthy men volunteers were divided into 4 groups: one group received no treatment (control group) while the others were incubated with 20, 40, and 50 µg/mL of T terrestris extract (experimental groups). Motility, viability, and DNA fragmentation were assessed in all groups. Results. The incubation of human semen with 40 and 50 μg/mL of T terrestris extract significantly enhanced total sperm motility, number of progressive motile spermatozoa, and curvilinear velocity over 60 to 120 minutes’ holding time (P terrestris extract (P terrestris extract to human sperm could affect male fertility capacity. PMID:27694560

  11. Tribulus terrestris Extract Improves Human Sperm Parameters In Vitro.

    Science.gov (United States)

    Khaleghi, Sara; Bakhtiari, Mitra; Asadmobini, Atefeh; Esmaeili, Farzane

    2016-09-30

    The object of present study was to investigate the effects of direct addition of Tribulus terrestris extract on human sperm parameters. Semen specimens from 40 healthy men volunteers were divided into 4 groups: one group received no treatment (control group) while the others were incubated with 20, 40, and 50 µg/mL of T terrestris extract (experimental groups). Motility, viability, and DNA fragmentation were assessed in all groups. The incubation of human semen with 40 and 50 μg/mL of T terrestris extract significantly enhanced total sperm motility, number of progressive motile spermatozoa, and curvilinear velocity over 60 to 120 minutes' holding time (P terrestris extract (P terrestris extract to human sperm could affect male fertility capacity. © The Author(s) 2016.

  12. GRAPHICAL MODELS OF THE AIRCRAFT MAINTENANCE PROCESS

    Directory of Open Access Journals (Sweden)

    Stanislav Vladimirovich Daletskiy

    2017-01-01

    Full Text Available The aircraft maintenance is realized by a rapid sequence of maintenance organizational and technical states, its re- search and analysis are carried out by statistical methods. The maintenance process concludes aircraft technical states con- nected with the objective patterns of technical qualities changes of the aircraft as a maintenance object and organizational states which determine the subjective organization and planning process of aircraft using. The objective maintenance pro- cess is realized in Maintenance and Repair System which does not include maintenance organization and planning and is a set of related elements: aircraft, Maintenance and Repair measures, executors and documentation that sets rules of their interaction for maintaining of the aircraft reliability and readiness for flight. The aircraft organizational and technical states are considered, their characteristics and heuristic estimates of connection in knots and arcs of graphs and of aircraft organi- zational states during regular maintenance and at technical state failure are given. It is shown that in real conditions of air- craft maintenance, planned aircraft technical state control and maintenance control through it, is only defined by Mainte- nance and Repair conditions at a given Maintenance and Repair type and form structures, and correspondingly by setting principles of Maintenance and Repair work types to the execution, due to maintenance, by aircraft and all its units mainte- nance and reconstruction strategies. The realization of planned Maintenance and Repair process determines the one of the constant maintenance component. The proposed graphical models allow to reveal quantitative correlations between graph knots to improve maintenance processes by statistical research methods, what reduces manning, timetable and expenses for providing safe civil aviation aircraft maintenance.

  13. Maintenance of radiation monitoring systems

    International Nuclear Information System (INIS)

    Aoyama, Kei

    2001-01-01

    As the safety and quality of atomic power facilities are more strongly required, the reliability improvement and preventive maintenance of radiation monitoring systems are important. This paper describes the maintenance of radiation monitoring systems delivered by Fuji Electric and the present status of preventive maintenance technology. Also it introduces the case that we developed a fault diagnosis function adopting a statistics technique and artificial intelligence (AI) and delivered a radiation monitoring system including this function. This system can output a fault analysis result and a countermeasure from the computer in real time. (author)

  14. Pacific Northwest Laboratory Maintenance Implementation plan

    International Nuclear Information System (INIS)

    Bright, J.D.

    1992-06-01

    This Maintenance Implementation plan has been developed for Pacific Northwest Laboratory's (PNL) Nuclear Facilities: 306W, 324, 325, 327 and 329NMF. It is based on a graded approach, self-assessment of the existing maintenance program(s) per the requirements specified by US Department of Energy (DOE) Order 4330.4A, Chapter II, Change number-sign 3. The results of this assessment were evaluated to determine needed improvements in PNL Craft Services' current maintenance program. The objective of this implementation plan is to provide baseline information for compliance to the DOE 4330.4A, and for needed improvements. The prime consideration in applying a graded approach to the Order has been to maintain safe and reliable operations, environmental compliance, safeguards and security, programmatic mission, facility preservation, and/or other facility-specific requirements. Using the results of the self-assessment, PNL has selected nine of the 18 elements of the Maintenance Program defined by DOE Order 4330.4A for improvement. The elements selected for improvement are Training and Qualification of Maintenance Personnel; Maintenance Procedures; Planning, Scheduling, and Coordination of Maintenance; Control of Maintenance Activities; Post-Maintenance Testing; Facility Condition Inspection; Management Involvement; Maintenance History; and Additional Maintenance Requirements. Based upon graded approach and current funding, those elements considered most important have been selected as goals for earliest compliance. Commitment dates for these elements have been established for compliance. The remaining elements of noncompliance will be targeted for implementation during later budget periods

  15. Proceedings of the third international conference on CANDU maintenance

    International Nuclear Information System (INIS)

    1995-01-01

    The third international conference on Candu maintenance included sessions on the following topics: predictive maintenance, reliability improvements, steam generator monitoring, tools and instrumentation, valve performance, fuel channel inspection and maintenance, steam generator maintenance, environmental qualification, predictive maintenance, instrumentation and control, steam generator cleaning, decontamination and radiation protection, inspection techniques, maintenance program strategies and valve packing experience, remote tooling/ robotics and fuel handling. The individual papers have been abstracted separately

  16. Proceedings of the third international conference on CANDU maintenance

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1996-12-31

    The third international conference on Candu maintenance included sessions on the following topics: predictive maintenance, reliability improvements, steam generator monitoring, tools and instrumentation, valve performance, fuel channel inspection and maintenance, steam generator maintenance, environmental qualification, predictive maintenance, instrumentation and control, steam generator cleaning, decontamination and radiation protection, inspection techniques, maintenance program strategies and valve packing experience, remote tooling/ robotics and fuel handling. The individual papers have been abstracted separately.

  17. Improved genetic manipulation of human embryonic stem cells.

    NARCIS (Netherlands)

    Braam, S.R.; Denning, C.; van den Brink, S.; Kats, P.; Hochstenbach, R.; Passier, R.; Mummery, C.L.

    2008-01-01

    Low efficiency of transfection limits the ability to genetically manipulate human embryonic stem cells (hESCs), and differences in cell derivation and culture methods require optimization of transfection protocols. We transiently transferred multiple independent hESC lines with different growth

  18. Maintenance of differentiation potential of human bone marrow mesenchymal stem cells immortalized by human telomerase reverse transcriptase gene despite [corrected] extensive proliferation

    DEFF Research Database (Denmark)

    Abdallah, Basem M; Haack-Sørensen, Mandana; Burns, Jorge S

    2005-01-01

    Human bone marrow mesenchymal stem cells (hMSC) represent a population of stem cells that are capable of differentiation into multiple lineages. However, these cells exhibit senescence-associated growth arrest and phenotypic changes during long-term in vitro culture. We have recently demonstrated...

  19. Unmanned Aerial Systems: Air Force and Army Should Improve Strategic Human Capital Planning for Pilot Workforces

    Science.gov (United States)

    2017-01-01

    the best UAS pilot candidates, including by conducting additional research and testing a tool that measures multitasking ability, a competency...UNMANNED AERIAL SYSTEMS Air Force and Army Should Improve Strategic Human Capital Planning for Pilot Workforces...Should Improve Strategic Human Capital Planning for Pilot Workforces What GAO Found The Air Force and the Army have not fully applied four of the five

  20. Human resource leadership: the key to improved results in health

    Directory of Open Access Journals (Sweden)

    O'Neil Mary L

    2008-06-01

    Full Text Available Abstract This article is the lead article in the Human Resources for Health journal's first quarterly feature. The series of seven articles has been contributed by Management Sciences for Health (MSH under the theme of leadership and management in public health and will be published article by article over the next few weeks. The journal has invited Dr Manuel M. Dayrit, Director of the WHO Department of Human Resources for Health and former Minister of Health for the Philippines to launch the feature with an opening editorial to be found in the journal's blog. This opening article describes the human resource challenges that managers around the world report and analyses why solutions often fail to be implemented. Despite rising attention to the acute shortage of health care workers, solutions to the human resource (HR crisis are difficult to achieve, especially in the poorest countries. Although we are aware of the issues and have developed HR strategies, the problem is that some old systems of leading and managing human resources for health do not work in today's context. The Leadership Development Program (LDP is grounded on the belief that good leadership and management can be learned and practiced at all levels. The case studies in this issue were chosen to illustrate results from using the LDP at different levels of the health sector. The LDP makes a profound difference in health managers' attitudes towards their work. Rather than feeling defeated by a workplace climate that lacks motivation, hope, and commitment to change, people report that they are mobilized to take action to change the status quo. The lesson is that without this capacity at all levels, global policy and national HR strategies will fail to make a difference.

  1. Human retinal gene therapy for Leber congenital amaurosis shows advancing retinal degeneration despite enduring visual improvement

    OpenAIRE

    Cideciyan, Artur V.; Jacobson, Samuel G.; Beltran, William A.; Sumaroka, Alexander; Swider, Malgorzata; Iwabe, Simone; Roman, Alejandro J.; Olivares, Melani B.; Schwartz, Sharon B.; Komáromy, András M.; Hauswirth, William W.; Aguirre, Gustavo D.

    2013-01-01

    The first retinal gene therapy in human blindness from RPE65 mutations has focused on safety and efficacy, as defined by improved vision. The disease component not studied, however, has been the fate of photoreceptors in this progressive retinal degeneration. We show that gene therapy improves vision for at least 3 y, but photoreceptor degeneration progresses unabated in humans. In the canine model, the same result occurs when treatment is at the disease stage equivalent to humans. The study ...

  2. Building Maintenance Management System for Heritage Museum

    Directory of Open Access Journals (Sweden)

    Md Azree Othuman Mydin

    2012-09-01

    Full Text Available An investment in the building maintenance aspect is massive throughout the world. In most of the countries, it signifies approximately 50% of the entire revenue of the construction industry. The value of buildings depends on the eminence of the maintenance invested in them. Maintenance management engages obtaining utmost advantage from the investment made on the maintenance activities. At the moment, maintenance in buildings in Malaysia is on the increase in spite of size, category, location, and ownership. This study focuses on Building Maintenance Management System for Heritage Museum, which consists of two case studies in Penang State Museum and Art Gallery, Malaysia and Museum of Perak, Malaysia. The aim of this study is to propose methods to improve the maintenance management system for heritage museum. From the results, the common problem occurs during the implementation for the maintenance of each building is the budget for the maintenance and worker’s skill. The department of each museum must have their own maintenance unit to keep an eye on the maintenance activities for their buildings in order to improve the maintenance management system in their building.

  3. The human milk project: a quality improvement initiative to increase human milk consumption in very low birth weight infants.

    Science.gov (United States)

    Ward, Laura; Auer, Christine; Smith, Carrie; Schoettker, Pamela J; Pruett, Raymond; Shah, Nilesh Y; Kotagal, Uma R

    2012-08-01

    Human milk has well-established health benefits for preterm infants. We conducted a multidisciplinary quality improvement effort aimed at providing at least 500 mL of human milk/kg in the first 14 days of life to very low birth weight (VLBW) (milk program, and twice-daily physician evaluation of infants' ability to tolerate feedings. The number of infants receiving at least 500 mL of human milk/kg in their first 14 days of life increased from 50% to 80% within 11 months of implementation, and this increase has been sustained for 4 years. Infants who met the feeding goal because they received donor milk increased each year. Since September 2007, infants have received, on average, 1,111 mL of human milk/kg. Approximately 4% of infants did not receive any human milk. Respiratory instability was the most frequent physiological reason given by clinicians for not initiating or advancing feedings in the first 14 days of life. Our quality improvement initiative resulted in a higher consumption of human milk in VLBW infants in the first 14 days of life. Other clinicians can use these described quality improvement methods and techniques to improve their VLBW babies' consumption of human milk.

  4. Maintenance Business Plans.

    Science.gov (United States)

    Adams, Matt

    2002-01-01

    Discusses maintenance business plans, statements which provide accountability for facilities maintenance organizations' considerable budgets. Discusses the plan's components: statement of plan objectives, macro and detailed description of the facility assets, maintenance function descriptions, description of key performance indicators, milestone…

  5. Maintenance Management Update.

    Science.gov (United States)

    Sternloff, Robert E.

    1987-01-01

    Current trends in park maintenance are overviewed, including maintenance impact statements, avoidance of cost through efficient use and national resource conservation, horticultural accomplishments that influence maintenance management, and vandalism prevention. (CB)

  6. Observations of human factors as a continuous improvement tool

    International Nuclear Information System (INIS)

    Almeida, P.

    2015-01-01

    Principles for Excellence in Human Performance should promote behaviors throughout an organization that support safety and reliable operation of the plant. Such behaviors must be clearly defined, communicated and reinforced by managers, on a continuous basis. To identify if workers behaviors are in compliance with those expected is paramount to have an observations program in place, which in one hand identifies deviations from expectations to correct them, and on the other promotes the desired behaviors through positive reinforcement. (Author)

  7. Improving the Translation of Animal Ischemic Stroke Studies to Humans

    OpenAIRE

    Jickling, Glen C; Sharp, Frank R

    2014-01-01

    Despite testing more than 1026 therapeutic strategies in models ischemic stroke and 114 therapies in human ischemic stroke, only one agent tissue plasminogen activator has successfully been translated to clinical practice as a treatment for acute stroke. Though disappointing, this immense body of work has led to a rethinking of animal stroke models and how to better translate therapies to patients with ischemic stroke. Several recommendations have been made, including the STAIR recommendation...

  8. Improving Human/Autonomous System Teaming Through Linguistic Analysis

    Science.gov (United States)

    Meszaros, Erica L.

    2016-01-01

    An area of increasing interest for the next generation of aircraft is autonomy and the integration of increasingly autonomous systems into the national airspace. Such integration requires humans to work closely with autonomous systems, forming human and autonomous agent teams. The intention behind such teaming is that a team composed of both humans and autonomous agents will operate better than homogenous teams. Procedures exist for licensing pilots to operate in the national airspace system and current work is being done to define methods for validating the function of autonomous systems, however there is no method in place for assessing the interaction of these two disparate systems. Moreover, currently these systems are operated primarily by subject matter experts, limiting their use and the benefits of such teams. Providing additional information about the ongoing mission to the operator can lead to increased usability and allow for operation by non-experts. Linguistic analysis of the context of verbal communication provides insight into the intended meaning of commonly heard phrases such as "What's it doing now?" Analyzing the semantic sphere surrounding these common phrases enables the prediction of the operator's intent and allows the interface to supply the operator's desired information.

  9. Smad mediated regulation of inhibitor of DNA binding 2 and its role in phenotypic maintenance of human renal proximal tubule epithelial cells.

    Directory of Open Access Journals (Sweden)

    Mangalakumar Veerasamy

    Full Text Available The basic-Helix-Loop-Helix family (bHLH of transcriptional factors plays a major role in regulating cellular proliferation, differentiation and phenotype maintenance. The downregulation of one of the members of bHLH family protein, inhibitor of DNA binding 2 (Id2 has been shown to induce de-differentiation of epithelial cells. Opposing regulators of epithelial/mesenchymal phenotype in renal proximal tubule epithelial cells (PTEC, TGFβ1 and BMP7 also have counter-regulatory effects in models of renal fibrosis. We investigated the regulation of Id2 by these growth factors in human PTECs and its implication in the expression of markers of epithelial versus myofibroblastic phenotype. Cellular Id2 levels were reduced by TGFβ1 treatment; this was prevented by co-incubation with BMP7. BMP7 alone increased cellular levels of Id2. TGFβ1 and BMP7 regulated Id2 through Smad2/3 and Smad1/5 dependent mechanisms respectively. TGFβ1 mediated Id2 suppression was essential for α-SMA induction in PTECs. Although Id2 over-expression prevented α-SMA induction, it did not prevent E-cadherin loss under the influence of TGFβ1. This suggests that the loss of gate keeper function of E-cadherin alone may not necessarily result in complete EMT and further transcriptional re-programming is essential to attain mesenchymal phenotype. Although BMP7 abolished TGFβ1 mediated α-SMA expression by restoring Id2 levels, the loss of Id2 was not sufficient to induce α-SMA expression even in the context of reduced E-cadherin expression. Hence, a reduction in Id2 is critical for TGFβ1-induced α-SMA expression in this model of human PTECs but is not sufficient in it self to induce α-SMA even in the context of reduced E-cadherin.

  10. Improving HOG with image segmentation: application to human detection

    NARCIS (Netherlands)

    Salas, Y.S.; Bermudez, D.V.; Peña, A.M.L.; Gomez, D.G.; Gevers, T.

    2012-01-01

    In this paper we improve the histogram of oriented gradients (HOG), a core descriptor of state-of-the-art object detection, by the use of higher-level information coming from image segmentation. The idea is to re-weight the descriptor while computing it without increasing its size. The benefits of

  11. TECHNICAL MAINTENANCE EFFICIENCY OF THE AIRCRAFT MAINTENANCE-FREE ON-BOARD SYSTEM BETWEEN SCHEDULED MAINTENANCES

    Directory of Open Access Journals (Sweden)

    A. M. Bronnikov

    2017-01-01

    Full Text Available The avionics concept of the maintenance-free on-board equipment implies the absence of necessity to maintain onboard systems between scheduled maintenance, preserving the required operational and technical characteristics; it should be achieved by automatic diagnosis of the technical condition and the application of active means of ensuring a failsafe design, allowing to change the structure of the system to maintain its functions in case of failure. It is supposed that such equipment will reduce substantially and in the limit eliminate traditional maintenance of aircraft between scheduled maintenance, ensuring maximum readiness for use, along with improving safety. The paper proposes a methodology for evaluating the efficiency of maintenance-free between scheduled maintenance aircraft system with homogeneous redundancy. The excessive redundant elements allow the system to accumulate failures which are repaired during the routine maintenance. If the number of failures of any reserve is approaching a critical value, the recovery of the on-board system (elimination of all failures is carried out between scheduled maintenance by conducting rescue and recovery operations. It is believed that service work leads to the elimination of all failures and completely updates the on-board system. The process of system operational status changes is described with the discrete-continuous model in the flight time. The average losses in the sorties and the average cost of operation are used as integrated efficiency indicators of system operation. For example, the evaluation of the operation efficiency of formalized on-board system with homogeneous redundancy demonstrates the efficiency of the proposed methodology and the possibility of its use while analyzing the efficiency of the maintenance-free operation equipment between scheduled periods. As well as a comparative analysis of maintenance-free operation efficiency of the on-board system with excessive

  12. Using Empathy to Improve Human-Robot Relationships

    Science.gov (United States)

    Pereira, André; Leite, Iolanda; Mascarenhas, Samuel; Martinho, Carlos; Paiva, Ana

    For robots to become our personal companions in the future, they need to know how to socially interact with us. One defining characteristic of human social behaviour is empathy. In this paper, we present a robot that acts as a social companion expressing different kinds of empathic behaviours through its facial expressions and utterances. The robot comments the moves of two subjects playing a chess game against each other, being empathic to one of them and neutral towards the other. The results of a pilot study suggest that users to whom the robot was empathic perceived the robot more as a friend.

  13. 340 Facility maintenance implementation plan

    International Nuclear Information System (INIS)

    1995-03-01

    This Maintenance Implementation Plan (MIP) has been developed for maintenance functions associated with the 340 Facility. This plan is developed from the guidelines presented by Department of Energy (DOE) Order 4330.4B, Maintenance Management Program (DOE 1994), Chapter II. The objective of this plan is to provide baseline information for establishing and identifying Westinghouse Hanford Company (WHC) conformance programs and policies applicable to implementation of DOE order 4330.4B guidelines. In addition, this maintenance plan identifies the actions necessary to develop a cost-effective and efficient maintenance program at the 340 Facility. Primary responsibility for the performance and oversight of maintenance activities at the 340 Facility resides with Westinghouse Hanford Company (WHC). Maintenance at the 340 Facility is performed by ICF-Kaiser Hanford (ICF-KH) South Programmatic Services crafts persons. This 340 Facility MIP provides interface requirements and responsibilities as they apply specifically to the 340 Facility. This document provides an implementation schedule which has been developed for items considered to be deficient or in need of improvement. The discussion sections, as applied to implementation at the 340 Facility, have been developed from a review of programs and practices utilizing the graded approach. Biennial review and additional reviews are conducted as significant programmatic and mission changes are made. This document is revised as necessary to maintain compliance with DOE requirements

  14. 340 Facility maintenance implementation plan

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1995-03-01

    This Maintenance Implementation Plan (MIP) has been developed for maintenance functions associated with the 340 Facility. This plan is developed from the guidelines presented by Department of Energy (DOE) Order 4330.4B, Maintenance Management Program (DOE 1994), Chapter II. The objective of this plan is to provide baseline information for establishing and identifying Westinghouse Hanford Company (WHC) conformance programs and policies applicable to implementation of DOE order 4330.4B guidelines. In addition, this maintenance plan identifies the actions necessary to develop a cost-effective and efficient maintenance program at the 340 Facility. Primary responsibility for the performance and oversight of maintenance activities at the 340 Facility resides with Westinghouse Hanford Company (WHC). Maintenance at the 340 Facility is performed by ICF-Kaiser Hanford (ICF-KH) South Programmatic Services crafts persons. This 340 Facility MIP provides interface requirements and responsibilities as they apply specifically to the 340 Facility. This document provides an implementation schedule which has been developed for items considered to be deficient or in need of improvement. The discussion sections, as applied to implementation at the 340 Facility, have been developed from a review of programs and practices utilizing the graded approach. Biennial review and additional reviews are conducted as significant programmatic and mission changes are made. This document is revised as necessary to maintain compliance with DOE requirements.

  15. Edible Mushrooms: Improving Human Health and Promoting Quality Life

    Directory of Open Access Journals (Sweden)

    María Elena Valverde

    2015-01-01

    Full Text Available Mushrooms have been consumed since earliest history; ancient Greeks believed that mushrooms provided strength for warriors in battle, and the Romans perceived them as the “Food of the Gods.” For centuries, the Chinese culture has treasured mushrooms as a health food, an “elixir of life.” They have been part of the human culture for thousands of years and have considerable interest in the most important civilizations in history because of their sensory characteristics; they have been recognized for their attractive culinary attributes. Nowadays, mushrooms are popular valuable foods because they are low in calories, carbohydrates, fat, and sodium: also, they are cholesterol-free. Besides, mushrooms provide important nutrients, including selenium, potassium, riboflavin, niacin, vitamin D, proteins, and fiber. All together with a long history as food source, mushrooms are important for their healing capacities and properties in traditional medicine. It has reported beneficial effects for health and treatment of some diseases. Many nutraceutical properties are described in mushrooms, such as prevention or treatment of Parkinson, Alzheimer, hypertension, and high risk of stroke. They are also utilized to reduce the likelihood of cancer invasion and metastasis due to antitumoral attributes. Mushrooms act as antibacterial, immune system enhancer and cholesterol lowering agents; additionally, they are important sources of bioactive compounds. As a result of these properties, some mushroom extracts are used to promote human health and are found as dietary supplements.

  16. Maintenance of differentiation potential of human bone marrow mesenchymal stem cells immortalized by human telomerase reverse transcriptase gene despite of extensive proliferation

    International Nuclear Information System (INIS)

    Abdallah, Basem M.; Haack-Sorensen, Mandana; Burns, Jorge S.; Elsnab, Birgitte; Jakob, Franz; Hokland, Peter; Kassem, Moustapha

    2005-01-01

    Human bone marrow mesenchymal stem cells (hMSC) represent a population of stem cells that are capable of differentiation into multiple lineages. However, these cells exhibit senescence-associated growth arrest and phenotypic changes during long-term in vitro culture. We have recently demonstrated that overexpression of human telomerase reverse transcriptase (hTERT) in hMSC reconstitutes telomerase activity and extends life span of the cells [Nat. Biotechnol. 20 (2002) 592]. In the present study, we have performed extensive characterization of three independent cell lines derived from the parental hMSC-TERT cell line based on different plating densities during expansion in culture: 1:2 (hMSC-TERT2), 1:4 (hMSC-TERT4), and 1:20 (hMSC-TERT20). The 3 cell lines exhibited differences in morphology and growth rates but they all maintained the characteristics of self-renewing stem cells and the ability to differentiate into multiple mesoderm-type cell lineages: osteoblasts, adipocytes, chondrocytes, and endothelial-like cells over a 3-year period in culture. Also, surface marker studies using flow cytometry showed a pattern similar to that known from normal hMSC. Thus, telomerization of hMSC by hTERT overexpression maintains the stem cell phenotype of hMSC and it may be a useful tool for obtaining enough number of cells with a stable phenotype for mechanistic studies of cell differentiation and for tissue engineering protocols

  17. Improving human papilloma virus vaccination rates throughout military treatment facilities.

    Science.gov (United States)

    Dawson, Rachel; Lemmon, Keith; Trivedi, Nidhi J; Hansen, Shana

    2018-03-07

    The four objectives of this study were to (1) educate military healthcare providers on HPV disease and vaccine, (2) assess short term recall of information presented at educational sessions, (3) assess provider comfort level with the vaccine, and (4) assess improvement in HPV vaccination rates. Standardized interactive educational sessions were conducted at military primary care clinics with pre- and post-educational quizzes administered before and immediately following the sessions. Provider attitudes were assessed using Likert scale questionnaires. Vaccination rates in children and young adolescents ages 11-18 at one of the participating regions that had a champion and started a Quality Improvement (QI) project were assessed at baseline, at 3-months and at 6-months post sessions. 200 providers were reached at 48 primary care clinics during May 2014 through October 2015 with 200 quizzes and Likert scale questionnaires returned. There was increase in knowledge following the educational sessions as revealed in the pre- and post- test scores [t(57) = -5.04, p knowledge recall and comfort level in answering parents' questions was seen. We found that educational sessions can improve HPV vaccination rates in military clinics that have a vaccine champion for up to 3-months. Further research into the effects of having clinic vaccine champions is critical. Copyright © 2018. Published by Elsevier Ltd.

  18. Reducing maintenance costs

    International Nuclear Information System (INIS)

    Zaiss, W.; Reuschle, K.; Baier, B.

    2002-01-01

    The increasingly more expensive maintenance measures, cuts in the cost budget, and the loss of know-how on the part of vendors all require a change of policy with respect to maintenance concepts of the part of operators. This also applies to the existing valve concepts, the drives included. Under these aspects, the current drive, which is self-actuated and actuated by outside media, for a parallel-plate valve of a nomial width of 700 was reconsidered. The effort served to reduce maintenance costs and, at the same time, simplify the drive concept as well as cut back on the number of in-service inspections. Moreover, the number of active components were to be minimized and installation conditions in the plant were to be improved. When the boundary conditions to be observed with respect to process technology had been laid down, the competent technical department developed a concept of modification of the drive. A major constituent part was the demonstration of the functioning capability of the new drive under accident conditions. It was achieved mainly by an analytical approach. In the resultant drive concept, the same control valves are employed to actuate a driving cylinder by means of self-actuation or by an outside medium as a function of pressure. (orig.) [de

  19. Laboratory simulation of maintenance activity

    International Nuclear Information System (INIS)

    Kantowitz, B.H.

    1988-01-01

    Laboratory research in highly controlled settings can augment, but not replace, studies in plant or training center locations. A laboratory simulation involves abstraction of the human information processing and social interactions required in prototypical maintenance tasks. A variety of independent variables can be studied quickly, efficiently, and at relatively low cost. Sources of human error can be identified in terms of models of human perception, cognition, action, attention, and social/organizational processes. This paper discusses research in progress at the Battelle Human Performance Laboratory. Both theoretical aspects and practical implications are considered. Directions for future human factors research are indicated

  20. Managing and controlling maintenance

    International Nuclear Information System (INIS)

    Chavez, G.; Perla, H.F.

    1980-01-01

    A well-planned maintenance-management program can bring organized yet flexible scheduling, improved productivity, and a ready-access data bank. The system detailed in the article, developed for a nuclear power plant, has application to any equipment-intensive facility. Key features of the system include: documentation of all work requirements and their completion; automated prioritizing of work orders; automatic generation of work orders for repetitive work, when due; work lists in priority sequence; deferred, standby, and outage work reports; labor and work-order backlog information; equipment work histories and cumulative failure data

  1. Prototyping visual interface for maintenance and supply databases

    OpenAIRE

    Fore, Henry Ray

    1989-01-01

    Approved for public release; distribution is unlimited This research examined the feasibility of providing a visual interface to standard Army Management Information Systems at the unit level. The potential of improving the Human-Machine Interface of unit level maintenance and supply software, such as ULLS (Unit Level Logistics System), is very attractive. A prototype was implemented in GLAD (Graphics Language for Database). GLAD is a graphics object-oriented environment for databases t...

  2. A Situational Maintenance Model

    DEFF Research Database (Denmark)

    Luxhoj, James T.; Thorsteinsson, Uffe; Riis, Jens Ove

    1997-01-01

    An overview of trend in maintenance management and presentation of a situational model and an analytical tools for identification of managerial efforts in maintenance.......An overview of trend in maintenance management and presentation of a situational model and an analytical tools for identification of managerial efforts in maintenance....

  3. A study on mobile PC display design in NPP maintenance considering the level of expertise

    International Nuclear Information System (INIS)

    Kim, In

    2010-02-01

    Recently, the importance of effective maintenance in nuclear power plants (NPPs) has been emphasized and research into effective maintenance by adopting mobile maintenance aids (MMAs) have been attempted. MMAs are currently used during operation and maintenance in NPPs, but no method that considers the limitations of mobile devices has been proposed. For improved and effective use, an MMA display design method based on abstraction hierarchy (AH) is proposed and its design considerations are discussed in this study. Six levels of abstraction hierarchy are proposed in this paper to classify the maintenance information. By classifying and organizing maintenance information using AH, maintenance information can be used effectively by users either high or low levels of expertise. When information classification has been finished, the information requirements and relationships for MMA design is extracted from the analysis of the AH result. Representative human-machine interface (HMI) guidelines issued by the US NRC, which are generally used in NPPs, are applied. With the considerations of MMA design analysis and practical guidelines, AH-based MMA is designed for maintenance tasks. An experiment is conducted using the AH-based MMA in order to estimate the effectiveness of the proposed method for maintenance tasks and to identify design considerations to enhance the proposed MMAs. The result indicated that an AH-based manual was more effective than a conventional manual in terms of task completion time and number of errors. The workload for the AH-based manual was estimated to be less than the conventional manual for low levels of expertise. However, a conventional manual was more comprehensive than the proposed manual and the steps contained in the maintenance manual were easier to remember. As the level of expertise increases, subjects tended to follow more abstract information while the number of navigations decreased. It is believed that when mobile devices become

  4. Aerobic Exercise Training Improves Orthostatic Tolerance in Aging Humans.

    Science.gov (United States)

    Xu, Diqun; Wang, Hong; Chen, Shande; Ross, Sarah; Liu, Howe; Olivencia-Yurvati, Albert; Raven, Peter B; Shi, Xiangrong

    2017-04-01

    This study was designed to test the hypothesis that aerobic exercise training of the elderly will increase aerobic fitness without compromising orthostatic tolerance (OT). Eight healthy sedentary volunteers (67.0 ± 1.7 yr old, four women) participated in 1 yr of endurance exercise training (stationary bicycle and/or treadmill) program at the individuals' 65%-75% of HRpeak. Peak O2 uptake (V˙O2peak) and HRpeak were determined by a maximal exercise stress test using a bicycle ergometer. Carotid baroreceptor reflex (CBR) control of HR and mean arterial pressure (MAP) were assessed by a neck pressure-neck suction protocol. Each subject's maximal gain (Gmax), or sensitivity, of the CBR function curves were derived from fitting their reflex HR and MAP responses to the corresponding neck pressure-neck suction stimuli using a logistic function curve. The subjects' OT was assessed using lower-body negative pressure (LBNP) graded to -50 mm Hg; the sum of the product of LBNP intensity and time (mm Hg·min) was calculated as the cumulative stress index. Training increased V˙O2peak (before vs after: 22.8 ± 0.92 vs 27.9 ± 1.33 mL·min·kg, P stress index was increased from 767 ± 68 mm Hg·min pretraining to 946 ± 44 mm Hg·min posttraining (P Aerobic exercise training improved the aerobic fitness and OT in elderly subjects. An improved OT is likely associated with an enhanced CBR function that has been reset to better maintain cerebral perfusion and cerebral tissue oxygenation during LBNP.

  5. Lean thinking for a maintenance process

    Directory of Open Access Journals (Sweden)

    Sherif Mostafa

    2015-01-01

    Full Text Available The maintenance process shares significant operating costs in an organisation. Lean thinking can be incorporated into maintenance activities through applying its principles and practices/tools. Lean maintenance (LM is a prerequisite for lean manufacturing systems. This research proposes a new structure for LM process based on a systematic literature review of a significant number of related articles that were published on LM. The process structure is designed based on the five lean principles to guide and support organisations to pursue maintenance excellence. This study establishes a scheme for LM tools that are structured into 2 level 4 bundles and 26 lean practices/tools and develops a House of Waste (HoW to demonstrate the association between maintenance wastes and the LM tools. With a successful accomplishment of the proposed scheme, the performance of a maintenance department can create more improvement opportunities over time to reach the maintenance excellence status.

  6. Analysis on nuclear power plant control room system design and improvement based on human factor engineering

    International Nuclear Information System (INIS)

    Gao Feng; Liu Yanzi; Sun Yongbin

    2014-01-01

    The design of nuclear power plant control room system is a process of improvement with the implementation of human factor engineering theory and guidance. The method of implementation human factor engineering principles into the nuclear power plant control room system design and improvement was discussed in this paper. It is recommended that comprehensive address should be done from control room system function, human machine interface, digital procedure, control room layout and environment design based on the human factor engineering theory and experience. The main issues which should be paid more attention during the control room system design and improvement also were addressed in this paper, and then advices and notices for the design and improvement of the nuclear power plant control room system were afforded. (authors)

  7. Mitochondrial DNA maintenance is regulated in human hepatoma cells by glycogen synthase kinase 3β and p53 in response to tumor necrosis factor α.

    Science.gov (United States)

    Vadrot, Nathalie; Ghanem, Sarita; Braut, Françoise; Gavrilescu, Laura; Pilard, Nathalie; Mansouri, Abdellah; Moreau, Richard; Reyl-Desmars, Florence

    2012-01-01

    During chronic liver inflammation, up-regulated Tumor Necrosis Factor alpha (TNF-α) targets hepatocytes and induces abnormal reactive oxygen species (ROS) production responsible for mitochondrial DNA (mtDNA) alterations. The serine/threonine Glycogen Synthase Kinase 3 beta (GSK3β) plays a pivotal role during inflammation but its involvement in the maintenance of mtDNA remains unknown. The aim of this study was to investigate its involvement in TNF-α induced mtDNA depletion and its interrelationship with p53 a protein known to maintain mtDNA copy numbers. Using quantitative polymerase chain reaction (qPCR) we found that at 30 min in human hepatoma HepG2 cells TNF-α induced 0.55±0.10 mtDNA lesions per 10 Kb and a 52.4±2.8% decrease in mtDNA content dependent on TNF-R1 receptor and ROS production. Both lesions and depletion returned to baseline from 1 to 6 h after TNF-α exposure. Luminol-amplified chemiluminescence (LAC) was used to measure the rapid (10 min) and transient TNF-α induced increase in ROS production (168±15%). A transient 8-oxo-dG level of 1.4±0.3 ng/mg DNA and repair of abasic sites were also measured by ELISA assays. Translocation of p53 to mitochondria was observed by Western Blot and co-immunoprecipitations showed that TNF-α induced p53 binding to GSK3β and mitochondrial transcription factor A (TFAM). In addition, mitochondrial D-loop immunoprecipitation (mtDIP) revealed that TNF-α induced p53 binding to the regulatory D-loop region of mtDNA. The knockdown of p53 by siRNAs, inhibition by the phosphoSer(15)p53 antibody or transfection of human mutant active GSK3βS9A pcDNA3 plasmid inhibited recovery of mtDNA content while blockade of GSK3β activity by SB216763 inhibitor or knockdown by siRNAs suppressed mtDNA depletion. This study is the first to report the involvement of GSK3β in TNF-α induced mtDNA depletion. We suggest that p53 binding to GSK3β, TFAM and D-loop could induce recovery of mtDNA content through mtDNA repair.

  8. Mitochondrial DNA maintenance is regulated in human hepatoma cells by glycogen synthase kinase 3β and p53 in response to tumor necrosis factor α.

    Directory of Open Access Journals (Sweden)

    Nathalie Vadrot

    Full Text Available During chronic liver inflammation, up-regulated Tumor Necrosis Factor alpha (TNF-α targets hepatocytes and induces abnormal reactive oxygen species (ROS production responsible for mitochondrial DNA (mtDNA alterations. The serine/threonine Glycogen Synthase Kinase 3 beta (GSK3β plays a pivotal role during inflammation but its involvement in the maintenance of mtDNA remains unknown. The aim of this study was to investigate its involvement in TNF-α induced mtDNA depletion and its interrelationship with p53 a protein known to maintain mtDNA copy numbers. Using quantitative polymerase chain reaction (qPCR we found that at 30 min in human hepatoma HepG2 cells TNF-α induced 0.55±0.10 mtDNA lesions per 10 Kb and a 52.4±2.8% decrease in mtDNA content dependent on TNF-R1 receptor and ROS production. Both lesions and depletion returned to baseline from 1 to 6 h after TNF-α exposure. Luminol-amplified chemiluminescence (LAC was used to measure the rapid (10 min and transient TNF-α induced increase in ROS production (168±15%. A transient 8-oxo-dG level of 1.4±0.3 ng/mg DNA and repair of abasic sites were also measured by ELISA assays. Translocation of p53 to mitochondria was observed by Western Blot and co-immunoprecipitations showed that TNF-α induced p53 binding to GSK3β and mitochondrial transcription factor A (TFAM. In addition, mitochondrial D-loop immunoprecipitation (mtDIP revealed that TNF-α induced p53 binding to the regulatory D-loop region of mtDNA. The knockdown of p53 by siRNAs, inhibition by the phosphoSer(15p53 antibody or transfection of human mutant active GSK3βS9A pcDNA3 plasmid inhibited recovery of mtDNA content while blockade of GSK3β activity by SB216763 inhibitor or knockdown by siRNAs suppressed mtDNA depletion. This study is the first to report the involvement of GSK3β in TNF-α induced mtDNA depletion. We suggest that p53 binding to GSK3β, TFAM and D-loop could induce recovery of mtDNA content through mtDNA repair.

  9. Mejoras al programa de mantenimiento de máquinas deslodadoras para la extracción de aceite de palma // Improving the maintenance program of extracting fruit palm oil machines

    Directory of Open Access Journals (Sweden)

    Jesús Cabrera - Gómez

    2010-09-01

    Full Text Available ResumenLa aplicación de nuevos enfoques de mantenimiento a partir de la identificación de oportunidades demejora de la confiabilidad operacional y los elementos que la componen, es una necesidad paratodas las organizaciones que pretendan incrementar sus indicadores de eficiencia. Las máquinasque son objeto de estudio en el presente trabajo, pertenecen a una importante empresa cuyo objetoes la extracción de aceite a partir de los frutos de la palma africana. Estas máquinas son atendidas,en teoría, a partir de un programa de mantenimiento preventivo que ha demostrado limitaciones, todavez que la mayor parte de las intervenciones realizadas en los últimos años muestran un caráctereminentemente reactivo. A partir de la realización de un análisis en el que fueron establecidas lasfunciones, los fallos funcionales, los modos de fallo y sus efectos, se identificaron los requerimientosde mantenimiento de estas máquinas y las tareas necesarias para asegurar la continuidad de lasfunciones, las que se cocentraron en una propuesta de programa con marcada tendencia a lasactividades proactivas.Palabras claves: mantenimiento de equipos rotatorios, confiabilidad operacional, mantenimiento__________________________________________________________________________AbstractThe application of new maintenance approaches related with operational reliability improvement andits elements is a necessity for all enterprises that intend to increase efficiency indicators. The rotatingmachines studied in this paper belong to an important plant that extracts oil from African palm treefruits. These machines are submitted, in theory, to a preventive maintenance program, but actuallythe most of maintenance activities are reactive. An analysis in order to identify functions, functionalfailures, failure modes and failure effects was made. Maintenance tasks for assuring the continuity offunctions were also identified and concentred in a proposal with a very proactive

  10. A Human/Computer Learning Network to Improve Biodiversity Conservation and Research

    OpenAIRE

    Kelling, Steve; Gerbracht, Jeff; Fink, Daniel; Lagoze, Carl; Wong, Weng-Keen; Yu, Jun; Damoulas, Theodoros; Gomes, Carla

    2012-01-01

    In this paper we describe eBird, a citizen-science project that takes advantage of the human observational capacity to identify birds to species, which is then used to accurately represent patterns of bird occurrences across broad spatial and temporal extents. eBird employs artificial intelligence techniques such as machine learning to improve data quality by taking advantage of the synergies between human computation and mechanical computation. We call this a Human-Computer Learning Network,...

  11. An Improved Methodology to Overcome Key Issues in Human Fecal Metagenomic DNA Extraction

    DEFF Research Database (Denmark)

    Kumar, Jitendra; Kumar, Manoj; Gupta, Shashank

    2016-01-01

    Microbes are ubiquitously distributed in nature, and recent culture-independent studies have highlighted the significance of gut microbiota in human health and disease. Fecal DNA is the primary source for the majority of human gut microbiome studies. However, further improvement is needed to obta...

  12. Spatio-Temporal Layout of Human Actions for Improved Bag-of-Words Action Detection

    NARCIS (Netherlands)

    Burghouts, G.J.; Schutte, K.

    2013-01-01

    We investigate how human action recognition can be improved by considering spatio-temporal layout of actions. From literature, we adopt a pipeline consisting of STIP features, a random forest to quantize the features into histograms, and an SVM classifier. Our goal is to detect 48 human actions,

  13. Effect of tailored educational intervention to improve self-care maintenance and quality of life in postmenopausal osteoporotic women after a fragility fracture: the Guardian Angel® study.

    Science.gov (United States)

    Basilici Zannetti, Emanuela; D'Agostino, Fabio; Cittadini, Noemi; Feola, Maurizio; Pennini, Annalisa; Rao, Cecilia; Vellone, Ercole; Tarantino, Umberto; Alvaro, Rosaria

    2017-01-01

    Osteoporosis has a significant impact on affected patients. Healthcare providers should encourage postmenopausal women to improve self-care maintenance behaviors and quality of life following a fragility fracture. The aims of this study were to a) develop two new instruments for measuring, respectively, self-care maintenance and quality of life, in postmenopausal women with osteoporosis; b) evaluate the effectiveness of a tailored educational intervention to improve self-care maintenance and quality of life after a fragility fracture in postmenopausal women. For the first aim, a cross-sectional study will be performed; for the second aim, a multicenter, quasi-experimental, interventional design will be used. A convenience sample of postmenopausal women admitted to 44 hospitals in Italy with a diagnosis of bone fragility fracture will be enrolled and surveyed at 7, 30, 60 and 180 days after discharge. Trained nurses will conduct the educational intervention. The new instruments will allow the measurement of self-care and quality of life in postmenopausal women following a fragility fracture. Through tailored educational interventions, women can be helped to take their medications correctly, adopt a healthy lifestyle, reduce the occurrence of bone fractures, and have a better quality of life.

  14. An improvement of the applicability of human factors guidelines for coping with human factors issues in nuclear power plants

    International Nuclear Information System (INIS)

    Lee, Y. H.; Lee, J. Y.

    2003-01-01

    Human factors have been well known as one of the key factors to the system effectiveness as well as the efficiency and safety of nuclear power plants(NPPs). Human factors engineering(HFE) are included in periodic safety review(PSR) on the existing NPPs and the formal safety assessment for the new ones. However, HFE for NPPs is still neither popular in practice nor concrete in methodology. Especially, the human factors guidelines, which are the most frequent form of human factors engineering in practice, reveal the limitations in their applications. We discuss the limitations and their casual factors found in human factors guidelines in order to lesson the workload of HFE practitioners and to improve the applicability of human factors guidelines. According to the purposes and the phases of HFE for NPPs, more selective items and specified criteria should be prepared carefully in the human factors guidelines for the each HFE applications in practice. These finding on the human factors guidelines can be transferred to the other HFE application field, such as military, aviation, telecommunication, HCI, and product safety

  15. Methadone maintenance treatment programme reduces criminal activity and improves social well-being of drug users in China: a systematic review and meta-analysis.

    Science.gov (United States)

    Sun, Hua-Min; Li, Xiao-Yan; Chow, Eric P F; Li, Tong; Xian, Yun; Lu, Yi-Hua; Tian, Tian; Zhuang, Xun; Zhang, Lei

    2015-01-08

    Methadone maintenance treatment (MMT) has been implemented in China since 2004 and has expanded into a nationwide programme. This study aims to evaluate changes in social functioning, family relations and drug-related criminal behaviour among MMT clients in China. Systematic review and meta-analysis. Both English and Chinese literature databases, including PubMed, Chongqing VIP Chinese Science and Technology Journals Database (CQVIP), China National Knowledge Infrastructure (CNKI) and Wanfang Data, were comprehensively searched over the period 2004-2014 for studied indicators. Study selection, quality assessment and data extraction were conducted according to the PRISMA (preferred reporting items for systematic reviews and meta-analyses) Statement. Meta-analyses were conducted using Comprehensive Meta-Analysis Biostat software. Thirty-eight articles were included in this review (1 in English and 37 in Chinese). The self-reported arrest rate decreased from 13.1% (95% CI 9.1% to 18.5%) at baseline to 3.4% (95% CI 1.5% to 7.7%) and 4.3% (95% CI 1.6% to 11.4%) after 6 and 12 months of MMT intervention, respectively. The rate of drug selling decreased from 7.6% (95% CI 3.8% to 14.8%) at baseline to 1.9% (95% CI 0.6% to 6.2%) and 3.0% (95% CI 1.0% to 8.9%) after 6 and 12 months of intervention, respectively. Similarly, the rates of selling sex for drugs and drug-related crime decreased from 5.3% (95% CI 2.4% to 11.1%) and 9.9% (95% CI 6.8% to 14.2%) at baseline to 1.1% (95% CI 0.5% to 2.3%) and 3.4% (95% CI 2.5% to 4.5%) at 6 months, then to 0.8% (95% CI 0.3% to 1.9%) and 3.4% (95% CI 0.8% to 13.1%) at 12 months after treatment initiation, respectively. In contrast, the rate of employment of clients and the proportion of clients having a good relationship with their family increased substantially from 26.4% (95% CI 22.9% to 30.1%) and 37.9% (95% CI 32.0% to 44.2%) to 41.6% (95% CI 36.6% to 48.0%) and 59.6% (95% CI 48.1% to 70.2%) at 6 months, then to 59.8% (95

  16. Upgrade of maintenance technologies of Nuclear Power Plants

    International Nuclear Information System (INIS)

    Kamada, Kazuaki

    2005-01-01

    In order to enhance long-term safe and stable operation of Ikata Nuclear Power Plants (NPPs) in more efficient way, maintenance technology upgrade project was started aiming at establishment of simplified and efficient self-maintenance system with affiliated companies. Maintenance technique and supervisor qualification system was introduced after improvement and reinforcement of personnel education and training. Reflecting investigation of maintenance activities of US NPPs and productivity improvement in other industries, preventive maintenance optimization project had been performed such as introduction of key performance indicator (KPI), new system incorporating reliability-centered maintenance (RCM) and condition-based maintenance (CBM), and on-line monitoring and maintenance (OLM) based on risk assessment. Enterprise asset management (EAM) to establish information data base and total productive maintenance (TPM) action for every personnel to participate in self-maintenance was also introduced. (T. Tanaka)

  17. Mesenchymal stromal cells improve human islet function through released products and extracellular matrix.

    Science.gov (United States)

    Arzouni, Ahmed A; Vargas-Seymour, Andreia; Rackham, Chloe L; Dhadda, Paramjeet; Huang, Guo-Cai; Choudhary, Pratik; Nardi, Nance; King, Aileen J F; Jones, Peter M

    2017-12-01

    The aims of the present study were (i) to determine whether the reported beneficial effects of mesenchymal stromal cells (MSCs) on mouse islet function extend to clinically relevant human tissues (islets and MSCs), enabling translation into improved protocols for clinical human islet transplantation; and (ii) to identify possible mechanisms through which human MSCs influence human islet function. Human islets were co-cultured with human adipose tissue-derived MSCs (hASCs) or pre-treated with its products - extracellular matrix (ECM) and annexin A1 (ANXA1). Mouse islets were pre-treated with mouse MSC-derived ECM. Islet insulin secretory function was assessed in vitro by radioimmunoassay. Quantitative RT-PCR was used to screen human adipMSCs for potential ligands of human islet G-protein-coupled receptors. We show that co-culture with hASCs improves human islet secretory function in vitro , as measured by glucose-stimulated insulin secretion, confirming previous reports using rodent tissues. Furthermore, we demonstrate that these beneficial effects on islet function can be partly attributed to the MSC-derived products ECM and ANXA1. Our results suggest that hASCs have the potential to improve the quality of human islets isolated for transplantation therapy of Type 1 diabetes. Furthermore, it may be possible to achieve improvements in human islet quality in a cell-free culture system by using the MSC-derived products ANXA1 and ECM. © 2017 The Author(s). Published by Portland Press Limited on behalf of the Biochemical Society.

  18. Equipment Maintenance management support system based on statistical analysis of maintenance history data

    International Nuclear Information System (INIS)

    Shimizu, S.; Ando, Y.; Morioka, T.

    1990-01-01

    Plant maintenance is recently becoming important with the increase in the number of nuclear power stations and in plant operating time. Various kinds of requirements for plant maintenance, such as countermeasures for equipment degradation and saving maintenance costs while keeping up plant reliability and productivity, are proposed. For this purpose, plant maintenance programs should be improved based on equipment reliability estimated by field data. In order to meet these requirements, it is planned to develop an equipment maintenance management support system for nuclear power plants based on statistical analysis of equipment maintenance history data. The large difference between this proposed new method and current similar methods is to evaluate not only failure data but maintenance data, which includes normal termination data and some degree of degradation or functional disorder data for equipment and parts. So, it is possible to utilize these field data for improving maintenance schedules and to evaluate actual equipment and parts reliability under the current maintenance schedule. In the present paper, the authors show the objectives of this system, an outline of this system and its functions, and the basic technique for collecting and managing of maintenance history data on statistical analysis. It is shown, from the results of feasibility tests using simulation data of maintenance history, that this system has the ability to provide useful information for maintenance and the design enhancement

  19. The maintenance management for lean organization

    OpenAIRE

    Daniel D. GEORGESCU

    2010-01-01

    The goal of lean maintenance approach is to maintain organization international competitiveness. In the spirit of continuously improvement, in the paper it is shown how by adjusting some Lean manufacturing specific techniques for Total Productive Maintenance (TPM) system, was born new maintenance system named Lean TPM. This is a systemic approach with three techniques, which don’t exclude specific techniques of TPM pillars, but complete them: the 7Ss as a critical first step in any improvemen...

  20. A Field Study of Scale Economies in Software Maintenance

    OpenAIRE

    Rajiv D. Banker; Sandra A. Slaughter

    1997-01-01

    Software maintenance is a major concern for organizations. Productivity gains in software maintenance can enable redeployment of Information Systems resources to other activities. Thus, it is important to understand how software maintenance productivity can be improved. In this study, we investigate the relationship between project size and software maintenance productivity. We explore scale economies in software maintenance by examining a number of software enhancement projects at a large fi...

  1. Improvement of Radiation-Mediated Immunosuppression of Human NSCLC Tumour Xenografts in a Nude Rat Model

    Directory of Open Access Journals (Sweden)

    Sergey V. Tokalov

    2010-01-01

    Full Text Available Human tumour xenografts in a nude rat model have consistently been used as an essential part of preclinical studies for anticancer drugs activity in human. Commonly, these animals receive whole body irradiation to assure immunosuppression. But whole body dose delivery might be inhomogeneous and the resulting incomplete bone marrow depletion may modify tumour behaviour. To improve irradiation-mediated immunosuppression of human non-small cell lung cancer (NSCLC xenografts in a nude rat model irradiation (2 + 2 Gy from opposite sides of animals has been performed using a conventional X-ray tube. The described modification of whole body irradiation improves growth properties of human NSCLC xenografts in a nude rat model. The design of the whole body irradiation mediated immunosuppression described here for NSCLC xenografts may be useful for research applications involving other types of human tumours.

  2. Knowledge engineering thinking of maintenance

    International Nuclear Information System (INIS)

    2007-01-01

    Maintenance optimization problem could not always settled mathematically and was obliged to use quasi-optimum solution with omitting non-formulated limiting condition or neglecting part of optimization object. In such a case knowledge engineering thinking was encouraged. Maintenance of complicated plant and artificial system should be considered from artificial object (equipment/facility hardware and system), technical information and knowledge base, and organizational and human aspect or society and institution. Comprehensive management system in organization and society was necessary not only for assuring integrity of equipment but also for attaining higher performance, reliability and economics of system. For better judgment it was important to share mechanism to make use of more information with organization or whole society. It was required to create database and data mining for knowledge base management system of maintenance. Maintenance was called 'last fortress' to assure quality such as reliability and safety of required function of equipment. Strategic approach to develop maintenance technology under cooperation was considered. Life extension R and D road map was launched in 2005. (T. Tanaka)

  3. Unsurfaced Road Maintenance Management

    Science.gov (United States)

    1992-12-01

    This draft manual describes an unsurfaced road maintenance management system for use on military installations. This system is available in either a manual or computerized mode (Micro PAVER). The maintenance standards prescribed should protect Govern...

  4. Winter maintenance performance measure.

    Science.gov (United States)

    2016-01-01

    The Winter Performance Index is a method of quantifying winter storm events and the DOTs response to them. : It is a valuable tool for evaluating the States maintenance practices, performing post-storm analysis, training : maintenance personnel...

  5. Genetically modified human bone marrow derived mesenchymal stem cells for improving the outcome of human islet transplantation.

    Directory of Open Access Journals (Sweden)

    Vaibhav Mundra

    Full Text Available The objective of this study was to determine the potential of human bone marrow derived mesenchymal stem cells (hBMSCs as gene carriers for improving the outcome of human islet transplantation. hBMSCs were characterized for the expression of phenotypic markers and transduced with Adv-hVEGF-hIL-1Ra to overexpress human vascular endothelial growth factor (hVEGF and human interleukin-1 receptor antagonist (hIL-1Ra. Human islets were co-cultured with hBMSCs overexpressing hVEGF and hIL-1Ra. Islet viability was determined by membrane fluorescent method and glucose stimulation test. Transduced hBMSCs and human islets were co-transplanted under the kidney capsule of NOD.Cg-Prkdc(scid Il2rg(tm1Wjl /SzJ (NSG diabetic mice and blood glucose levels were measured over time to demonstrate the efficacy of genetically modified hBMSCs. At the end of study, immunofluorescent staining of kidney section bearing islets was performed for insulin and von Willebrand Factor (vWF. hBMSCs were positive for the expression of CD73, CD90, CD105, CD146 and Stro-1 surface markers as determined by flow cytometry. Transduction of hBMSCs with adenovirus did not affect their stemness and differentiation potential as confirmed by mRNA levels of stem cell markers and adipogenic differentiation of transduced hBMSCs. hBMSCs were efficiently transduced with Adv-hVEGF-hIL-1Ra to overexpress hVEGF and hIL-1Ra. Live dead cell staining and glucose stimulation test have shown that transduced hBMSCs improved the viability of islets against cytokine cocktail. Co-transplantation of human islets with genetically modified hBMSCs improved the glycemic control of diabetic NSG mice as determined by mean blood glucose levels and intraperitoneal glucose tolerance test. Immunofluorescent staining of kidney sections was positive for human insulin and vWF. In conclusion, our results have demonstrated that hBMSCs may be used as gene carriers and nursing cells to improve the outcome of islet

  6. Forecasts of the Maintenance Activity

    Directory of Open Access Journals (Sweden)

    Marius Romocea

    2017-11-01

    Full Text Available Enhancing the machines’ technical and technological performance through constructive improvements that allow for the automation of orders, contributes to the increasing of the production capacity of the system and for maintaining an optimal level of product costs. In order to achieve these goals, it is necessary to organize the maintenance work well, in order to quickly diagnose the malfunctions and to shorten the repair time. Given the scale of the phenomena, this paper seeks to answer two questions, namely: how will be the maintenance in future and also how to prepare this activity.

  7. Simulation based comparison of predictive maintenance policies

    NARCIS (Netherlands)

    Tinga, Tiedo; Janssen, R.H.P.; Steenbergen, R.; van Gelder, P.

    2013-01-01

    When an asset is operated in variable conditions, its operational efficiency can be improved significantly when the maintenance is performed in a dynamic manner. This means that variations in usage and operating environment are taken into account when deciding on the length of the maintenance

  8. [Development of Hospital Equipment Maintenance Information System].

    Science.gov (United States)

    Zhou, Zhixin

    2015-11-01

    Hospital equipment maintenance information system plays an important role in improving medical treatment quality and efficiency. By requirement analysis of hospital equipment maintenance, the system function diagram is drawed. According to analysis of input and output data, tables and reports in connection with equipment maintenance process, relationships between entity and attribute is found out, and E-R diagram is drawed and relational database table is established. Software development should meet actual process requirement of maintenance and have a friendly user interface and flexible operation. The software can analyze failure cause by statistical analysis.

  9. MOV predictive maintenance program at Darlington NGS

    International Nuclear Information System (INIS)

    Morrison, J.F.

    1992-01-01

    This paper details the Motor Operated Valve (MOV) Predictive Maintenance program at Darlington Nuclear Generating Station. The program encompasses the use of diagnostics tooling in conjunction with more standard maintenance techniques, with the goal of improving performance of MOV's. Problems encountered and solutions developed during the first two phases of this program are presented, along with proposed actions for the final trending phase of the program. This paper also touches on the preventive and corrective maintenance aspects of an overall MOV maintenance program. 6 refs., 6 tabs., 6 figs

  10. Asphalt in Pavement Maintenance.

    Science.gov (United States)

    Asphalt Inst., College Park, MD.

    Maintenance methods that can be used equally well in all regions of the country have been developed for the use of asphalt in pavement maintenance. Specific information covering methods, equipment and terminology that applies to the use of asphalt in the maintenance of all types of pavement structures, including shoulders, is provided. In many…

  11. Optimization of surface maintenance

    International Nuclear Information System (INIS)

    Oeverland, E.

    1990-01-01

    The present conference paper deals with methods of optimizing the surface maintenance of steel-made offshore installations. The paper aims at identifying important approaches to the problems regarding the long-range planning of an economical and cost effective maintenance program. The methods of optimization are based on the obtained experiences from the maintenance of installations on the Norwegian continental shelf. 3 figs

  12. Dukovany NPP maintenance management

    International Nuclear Information System (INIS)

    Siegel, F.

    2005-01-01

    Maintenance planning and management for the technological equipment of the Dukovany NPP are described. A Maintenance Control and Evaluation System has been developed and is in use to help manage the complex maintenance issue. Practical examples of outputs of the System, with a comprehensive use of the cost, reliability and safety related data, are presented. (author)

  13. Maintenance program decision-making utilizing crash data.

    Science.gov (United States)

    2013-07-01

    This document describes methods that may be used by UDOT Maintenance personnel to improve highway safety. Four programs have been recommended using crash data to make more informed decisions concerning maintenance programs as follows: : Snow & Ic...

  14. Cost savings from performance-based maintenance contracting

    NARCIS (Netherlands)

    Straub, A.

    2009-01-01

    New procurement approaches combined with performance-based building approaches should reduce costs, but empirical qualitative and quantitative studies are lacking. Performance-based maintenance contracts give maintenance suppliers incentives to improve their way of working. Innovative,

  15. A Real-Time Quantitative Condition Alerting and Analysis Support System for Aircraft Maintenance, Phase I

    Data.gov (United States)

    National Aeronautics and Space Administration — Financial constraints and the need for improved operational efficiency are requiring airlines to emphasize "on-condition" maintenance over scheduled maintenance...

  16. Overview of human performance improvement initiatives in Nuclear Power Plants (NPPs )

    International Nuclear Information System (INIS)

    Sharma, Ashok Kumar

    2006-01-01

    Nuclear Power Plants (NPPs) are very complex systems. Diverse, multiple and redundant technological systems are used for effective control and safety of the NPPs. The increased numbers of such systems require increased operator attention. Additionally, the control stations (man-machine interfaces) are to be kept manageable in size. This sometimes reduces the scope for truly ergonomic design. These limitations, coupled with the shortcomings of human nature, led to unintended human performance problems and errors resulting into poor plant performance worldwide. Some organisational weaknesses, managerial decisions and latent errors also aided and abetted human errors. In view of this, a need was felt for development of performance culture at all levels in NPP organisations. Towards this end, ready-to-use performance improvement tools were developed and used for individual performers, supervisors and managers in the NPPs. This paper describes the experiences of the global nuclear electricity generating industry towards human performance improvement and error reduction. (author)

  17. Using human factors engineering to improve the effectiveness of infection prevention and control.

    Science.gov (United States)

    Anderson, Judith; Gosbee, Laura Lin; Bessesen, Mary; Williams, Linda

    2010-08-01

    Human factors engineering is a discipline that studies the capabilities and limitations of humans and the design of devices and systems for improved performance. The principles of human factors engineering can be applied to infection prevention and control to study the interaction between the healthcare worker and the system that he or she is working with, including the use of devices, the built environment, and the demands and complexities of patient care. Some key challenges in infection prevention, such as delayed feedback to healthcare workers, high cognitive workload, and poor ergonomic design, are explained, as is how human factors engineering can be used for improvement and increased compliance with practices to prevent hospital-acquired infections.

  18. Architecture and Key Techniques of Augmented Reality Maintenance Guiding System for Civil Aircrafts

    Science.gov (United States)

    hong, Zhou; Wenhua, Lu

    2017-01-01

    Augmented reality technology is introduced into the maintenance related field for strengthened information in real-world scenarios through integration of virtual assistant maintenance information with real-world scenarios. This can lower the difficulty of maintenance, reduce maintenance errors, and improve the maintenance efficiency and quality of civil aviation crews. Architecture of augmented reality virtual maintenance guiding system is proposed on the basis of introducing the definition of augmented reality and analyzing the characteristics of augmented reality virtual maintenance. Key techniques involved, such as standardization and organization of maintenance data, 3D registration, modeling of maintenance guidance information and virtual maintenance man-machine interaction, are elaborated emphatically, and solutions are given.

  19. EPR design for maintenance

    International Nuclear Information System (INIS)

    Krugmann, U.

    1998-01-01

    Preventive maintenance is very important in achieving high plant availability. For the European Pressurized Reactor (EPR) preventive maintenance has been carefully addressed in the design stage. This is particularly necessary because of the traditionally different maintenance strategies employed in France and Germany. This paper emphasizes the following features introduced in the ERP design to minimize the duration of the refueling outage: (1) containment accessibility during power operation; (2) overall plant layout to facilitate inspections and maintenances within the containment; and (3) safety system design for enabling preventive maintenance during power operation. (author)

  20. Modern electronic maintenance principles

    CERN Document Server

    Garland, DJ

    2013-01-01

    Modern Electronic Maintenance Principles reviews the principles of maintaining modern, complex electronic equipment, with emphasis on preventive and corrective maintenance. Unfamiliar subjects such as the half-split method of fault location, functional diagrams, and fault finding guides are explained. This book consists of 12 chapters and begins by stressing the need for maintenance principles and discussing the problem of complexity as well as the requirements for a maintenance technician. The next chapter deals with the connection between reliability and maintenance and defines the terms fai

  1. Managing nuclear maintenance

    International Nuclear Information System (INIS)

    Anon.

    1990-01-01

    For utilities operating nuclear powerplants, the rules of the game continue to change. Conflicting regulatory pressures and a tougher competitive environment will make management's job more complicated and difficult in the 1990s. Dealing with these pressures successfully requires greater attention to maintenance effectiveness. Utilities can help shape their future environment by developing a well-planned strategy to guide their actions. Parts of the strategy that are discussed include developing a sound maintenance philosophy, selecting a service company, radiation exposure, and managing spare parts. This article also addresses the Swedish experience in maintenance, German philosophy regarding maintenance and the current maintenance practices of the Electricite de France

  2. AIRCRAFT MAINTENANCE HANGAR

    Directory of Open Access Journals (Sweden)

    GEAMBASU Gabriel George

    2017-05-01

    Full Text Available The paper presents the maintenance process that is done on an airplane, at a certain period of time, or after a number of flight hours or cycles and describes the checks performed behind each inspection. The first part of research describes the aircraft maintenance process that has to be done after an updated maintenance manual according with aircraft type, followed by a short introduction about maintenance hangar. The second part of the paper presents a hangar design with a foldable roof and walls, which can be folded or extended, over an airplane when a maintenance process is done, or depending on weather condition.

  3. Inspection of licensee - Maintenance programme and activities

    International Nuclear Information System (INIS)

    2013-01-01

    An effective maintenance programme is critical to sustained safe and reliable operation of nuclear power plants. The Working Group on Inspection Practices (WGIP) concluded that when a licensee has an effective maintenance programme, the overall operating safety of the plant is improved and the protection of public health and safety enhanced. All Regulatory Bodies (RB) consider maintenance to be an important area for oversight. Although a variety of inspection practices are being used; RB are actively monitoring licensee performance. Specifically the following conclusions were reached and commendable practices identified: - Maintenance oversight by regulators appears to be in a stable continuous improvement state. Most regulators are executing inspection oversight based on an existing regulatory framework. - The performance of a licensee's maintenance programme is recognized as important part of maintaining nuclear safety. The result of the maintenance program assessment is included in the overall performance assessment of a license. - Maintenance inspection activities are recognized as an important part of the regulatory oversight process. Inspection activities are based on the safety significance and nature of work being performed by the licensee. - The effectiveness of the maintenance inspection activities is recognized to rely on properly qualified inspectors; who are adequately supported by specialists. Training and qualification of inspectors should be based on how the RB reviews and inspects licensee maintenance programmes. - Reporting requirements are identified to provide information on the licensees maintenance programme, and to help guide inspection activities. - Performance Indicators are recognized as a useful tool for helping focus regulatory activities. Basic PI are identified and tracked by the RB, and use of PI by the licensee is monitored. - Inspections are designed to confirm that the licensee is planning and scheduling maintenance with due

  4. Predictors of improvement in subjective sleep quality reported by older adults following group-based cognitive behavior therapy for sleep maintenance and early morning awakening insomnia.

    Science.gov (United States)

    Lovato, Nicole; Lack, Leon; Wright, Helen; Kennaway, David J

    2013-09-01

    Cognitive behavior therapy is an effective nonpharmacologic treatment for insomnia. However, individualized administration is costly and often results in substantial variability in treatment response across individual patients, particularly so for older adults. Group-based administration has demonstrated impressive potential for a brief and inexpensive answer to the effective treatment of insomnia in the older population. It is important to identify potential predictors of response to such a treatment format to guide clinicians when selecting the most suitable treatment for their patients. The aim of our study was to identify factors that predict subjective sleep quality of older adults following group-based administration of cognitive behavior therapy for insomnia (CBT-I). Eighty-six adults (41 men; mean age, 64.10 y; standard deviation [SD], 6.80) with sleep maintenance or early morning awakening insomnia were selected from a community-based sample to participate in a 4-week group-based treatment program of CBT-I. Participants were required to complete 7-day sleep diaries and a comprehensive battery of questionnaires related to sleep quality and daytime functioning. Hierarchical multiple regression analyses were used to identify factors predicting subjective sleep quality immediately following treatment and at 3-month follow-up. Sleep diaries reported average nightly sleep efficiency (SE), which was used as the outcome measure of sleep quality. Participants with the greatest SE following treatment while controlling for pretreatment SE were relatively younger and had more confidence in their ability to sleep at pretreatment. These characteristics may be useful to guide clinicians when considering the use of a group-based CBT-I for sleep maintenance or early morning awakening insomnia in older adults. Copyright © 2013 Elsevier B.V. All rights reserved.

  5. HUMAN RESOURCES EMPOWERMENT, WORKING MOTIVATION AND ORGANIZATION CHANGE IN IMPROVING HOTEL BUSINESS PERFORMANCE IN BALI

    Directory of Open Access Journals (Sweden)

    Gusti Kade Sutawa

    2016-03-01

    Full Text Available This study aims to test and analyze impact of human resource development on working motivation of hotel business workers in Bali, impact of human resource development on organizational changes of hotel business in Bali, impact of human resource development on the performance of hotel business in Bali, impact of working motivation against organizational changes in hotel business in Bali, impact of working motivation on the organizations performance of the hotel business in Bali, and impact of organizational changes against organizations performance of the hotel business in Bali. There were 170 respondents of star-rated hotel employees which were selected through purposive sampling technique. Structural Equation Modeling with the application Analysis of Moment Structure was used to analyze the data. The results show that empowerment of human resources (HR has positive and significant impact on working motivation, organizational changes, and the organization performance of hotel business in Bali, working motivation has positive and significant impact on organizational changes and the organization performance of hotel business in Bali and organizational changes have significant and positive impact on the organization performance of hotel business in Bali. Empowerment variables have the most powerful impact to support the improvement of organizational performance, followed by organizational changes and working motivation variables. The results indicate that human resource empowerment improves the performance of the hotel business in Bali. Therefore, human resource development need to be prioritized in order to improve organizational performance of star hotels in Bali.

  6. Improving solubility and refolding efficiency of human V(H)s by a novel mutational approach.

    Science.gov (United States)

    Tanha, Jamshid; Nguyen, Thanh-Dung; Ng, Andy; Ryan, Shannon; Ni, Feng; Mackenzie, Roger

    2006-11-01

    The antibody V(H) domains of camelids tend to be soluble and to resist aggregation, in contrast to human V(H) domains. For immunotherapy, attempts have therefore been made to improve the properties of human V(H)s by camelization of a small set of framework residues. Here, we have identified through sequence comparison of well-folded llama V(H) domains an alternative set of residues (not typically camelid) for mutation. Thus, the solubility and thermal refolding efficiency of a typical human V(H), derived from the human antibody BT32/A6, were improved by introduction of two mutations in framework region (FR) 1 and 4 to generate BT32/A6.L1. Three more mutations in FR3 of BT32/A6.L1 further improved the thermal refolding efficiency while retaining solubility and cooperative melting profiles. To demonstrate practical utility, BT32/A6.L1 was used to construct a phage display library from which were isolated human V(H)s with good antigen binding activity and solubility. The engineered human V(H) domains described here may be useful for immunotherapy, due to their expected low immunogenicity, and in applications involving transient high temperatures, due to their efficient refolding after thermal denaturation.

  7. Hepatocyte nuclear factor 4A improves hepatic differentiation of immortalized adult human hepatocytes and improves liver function and survival.

    Science.gov (United States)

    Hang, Hua-Lian; Liu, Xin-Yu; Wang, Hai-Tian; Xu, Ning; Bian, Jian-Min; Zhang, Jian-Jun; Xia, Lei; Xia, Qiang

    2017-11-15

    Immortalized human hepatocytes (IHH) could provide an unlimited supply of hepatocytes, but insufficient differentiation and phenotypic instability restrict their clinical application. This study aimed to determine the role of hepatocyte nuclear factor 4A (HNF4A) in hepatic differentiation of IHH, and whether encapsulation of IHH overexpressing HNF4A could improve liver function and survival in rats with acute liver failure (ALF). Primary human hepatocytes were transduced with lentivirus-mediated catalytic subunit of human telomerase reverse transcriptase (hTERT) to establish IHH. Cells were analyzed for telomerase activity, proliferative capacity, hepatocyte markers, and tumorigenicity (c-myc) expression. Hepatocyte markers, hepatocellular functions, and morphology were studied in the HNF4A-overexpressing IHH. Hepatocyte markers and karyotype analysis were completed in the primary hepatocytes using shRNA knockdown of HNF4A. Nuclear translocation of β-catenin was assessed. Rat models of ALF were treated with encapsulated IHH or HNF4A-overexpressing IHH. A HNF4A-positive IHH line was established, which was non-tumorigenic and conserved properties of primary hepatocytes. HNF4A overexpression significantly enhanced mRNA levels of genes related to hepatic differentiation in IHH. Urea levels were increased by the overexpression of HNF4A, as measured 24h after ammonium chloride addition, similar to that of primary hepatocytes. Chromosomal abnormalities were observed in primary hepatocytes transfected with HNF4A shRNA. HNF4α overexpression could significantly promote β-catenin activation. Transplantation of HNF4A overexpressing IHH resulted in better liver function and survival of rats with ALF compared with IHH. HNF4A improved hepatic differentiation of IHH. Transplantation of HNF4A-overexpressing IHH could improve the liver function and survival in a rat model of ALF. Copyright © 2017 Elsevier Inc. All rights reserved.

  8. Knowledge based maintenance

    Energy Technology Data Exchange (ETDEWEB)

    Sturm, A [Hamburgische Electacitaets-Werke AG Hamburg (Germany)

    1998-12-31

    The establishment of maintenance strategies is of crucial significance for the reliability of a plant and the economic efficiency of maintenance measures. Knowledge about the condition of components and plants from the technical and business management point of view therefore becomes one of the fundamental questions and the key to efficient management and maintenance. A new way to determine the maintenance strategy can be called: Knowledge Based Maintenance. A simple method for determining strategies while taking the technical condition of the components of the production process into account to the greatest possible degree which can be shown. A software with an algorithm for Knowledge Based Maintenance leads the user during complex work to the determination of maintenance strategies for this complex plant components. (orig.)

  9. Knowledge based maintenance

    Energy Technology Data Exchange (ETDEWEB)

    Sturm, A. [Hamburgische Electacitaets-Werke AG Hamburg (Germany)

    1997-12-31

    The establishment of maintenance strategies is of crucial significance for the reliability of a plant and the economic efficiency of maintenance measures. Knowledge about the condition of components and plants from the technical and business management point of view therefore becomes one of the fundamental questions and the key to efficient management and maintenance. A new way to determine the maintenance strategy can be called: Knowledge Based Maintenance. A simple method for determining strategies while taking the technical condition of the components of the production process into account to the greatest possible degree which can be shown. A software with an algorithm for Knowledge Based Maintenance leads the user during complex work to the determination of maintenance strategies for this complex plant components. (orig.)

  10. Probabilistic analysis of free ways for maintenance

    International Nuclear Information System (INIS)

    Torres V, A.; Rivero O, J.J.

    2004-01-01

    The safety during the maintenance interventions is treated in limited manner and in general independent of the systems of management of the maintenance. This variable is affected by multiple technical or human factors many times subjective and difficult to quantifying, what limits the design of preventive plans. However, some factors constitute common points: the isolation configurations during the free ways (bank drafts in the oil industry) and the human errors associated to their violation. This characteristic allowed to develop the analysis of such situations through the methodology of fault trees that it links faults of teams and human errors cohesively. The methodology has been automated inside the MOSEG Win Ver 1.0 code and the same one can embrace from the analysis of a particular situation of free way until that of a complete strategy of maintenance from the point of view of the safety of the maintenance personal. (Author)

  11. Role of zinc in human body and approaches for improvement with reference to status in Pakistan

    International Nuclear Information System (INIS)

    Yameen, A.; Bilal, R.

    2001-01-01

    Importance of micronutrients for human health has been recognized and efforts are being made to eradicate their deficiency. Micronutrient deficiency is also termed as hidden hunger. Zinc is an important micronutrient and its deficiency cause serious effects on human health. This paper intends to describe the importance of zinc and methods of its assessment, highlighting the consequences of its deficiency in human body in order to create awareness. Some information on deficiency data in Pakistan, status of current national nutrition survey for future policies and possible measures to improve the zinc status of population is also mentioned. (author)

  12. Human performance in an operational event - how to improve it? An initiative in a French NPP

    International Nuclear Information System (INIS)

    Meslin, M.

    1998-01-01

    In the case of the Saint-Laurent-des-Eaux French nuclear power station, the author comments the elements and principles of human factor policy which have been implemented, the organizational implications of this implementation (building up of an internal human factors network), and briefly evokes studies and initiatives aimed at improving the quality of operation from a general point of view and through projects aiming at analyzing and at a valorisation of human reliability in activities dealing with reactor operation. He also comments the perception and appropriation of quality in the different departments

  13. Operations and maintenance - Safety challenges

    Energy Technology Data Exchange (ETDEWEB)

    Nielsen, Liv [Oljedirektoratet, Stavanger (Norway)

    1999-07-01

    With the unsteady oil prices and the possible consequences of the deregulation of the European energy markets one may expect further optimization of operating and maintenance costs. One may also expect extended use of various risk-based optimization techniques such as RCM (Reliability Centered Maintenance) and RBI (Risk Based Inspection). This presentation addresses the need for further research and development in this area. Maintenance work is necessary, but it can also create risk. The accident statistics show many examples of this. The Norwegian petroleum industry's ability to learn from previous incidents is questioned. Maintenance staff must be well trained and possess the necessary routines. Technical documentation must be updated. Uncertainties with respect to future oil and gas prices combined with the effect of the deregulation of the European energy markets will lead to even more focus on cost-effective operations and maintenance. The need for long-term research and development is stressed. Risk based techniques such as RCM and RBI are extensively used in the defence industry and the nuclear industry, but applying them to the petroleum industry requires improved risk models. Ageing effects such as corrosion, erosion, fatigue etc. can be expected, but the capability to predict, monitor and control them should be improved. At present, not even the most sophisticated risk analysis can model ageing effects. The importance of efficient use of information technology (IT) is stressed. Improving the product quality and safety often requires new technology and so research and development is important. Close cooperation with the industry is required.

  14. Progress with the national infrastructure maintenance strategy

    CSIR Research Space (South Africa)

    Wall, K

    2008-07-01

    Full Text Available infrastructure investment and maintenance that will result from this strategy will not only improve infrastructure performance and underpin services sustainability, but will also contribute significantly towards national and local economic growth and will add...

  15. The maintenance management for lean organization

    Directory of Open Access Journals (Sweden)

    Daniel D. GEORGESCU

    2010-12-01

    Full Text Available The goal of lean maintenance approach is to maintain organization international competitiveness. In the spirit of continuously improvement, in the paper it is shown how by adjusting some Lean manufacturing specific techniques for Total Productive Maintenance (TPM system, was born new maintenance system named Lean TPM. This is a systemic approach with three techniques, which don’t exclude specific techniques of TPM pillars, but complete them: the 7Ss as a critical first step in any improvement program; instantaneous maintenance; improvement setup operations. In the spirit of Lean principle, Lean TPM adjusts overall equipment effectiveness concept for all supply-chain from supplier to customer. Maintaining equipment in its optimal state and continually improving its productivity is the whole strategy behind Lean TPM.

  16. South Blackwater Coal`s maintenance program

    Energy Technology Data Exchange (ETDEWEB)

    Nash, J. [South Blackwater Coal Limited, Blackwater, Qld. (Australia)

    1998-09-01

    The South Blackwater operation consists of two opencut mining areas and two underground mines (Laleham and Kenmure) near Blackwater in central Queensland, all of which supply coal to a central coal preparation plant. South Blackwater Coal Ltd. recently developed a maintenance improvement programme, described in this article. The programme involved implementation systems of key performance indicators (KPIs), benchmaking, condition monitoring, work planning and control, failure analysis and maintenance audit. Some improvements became almost immediately apparent, others were quite gradual. Major results included: improved availability (and reliability) of all opencast fleets, improvements in rear dump availability; reduced maintenance man-hours for opencast fleets; and increased availability of the coal handling and preparation plant. The paper is an edited version of that presented at the `Maintenance in mining conference` 16-19 March 1998, held in Bali, Indonesia. 4 figs., 2 photos.

  17. 49 CFR 260.39 - Maintenance standards.

    Science.gov (United States)

    2010-10-01

    ... REHABILITATION AND IMPROVEMENT FINANCING PROGRAM Standards for Maintenance of Facilities Involved in the Project... the project. (b) When the proceeds of a direct loan or an obligation guaranteed by the Administrator...

  18. Recombinant human endostatin improves tumor vasculature and alleviates hypoxia in Lewis lung carcinoma

    International Nuclear Information System (INIS)

    Peng Fang; Wang Jin; Zou Yi; Bao Yong; Huang Wenlin; Chen Guangming; Luo Xianrong; Chen Ming

    2011-01-01

    Objective: To investigate whether recombinant human endostatin can create a time window of vascular normalization prior to vascular pruning to alleviate hypoxia in Lewis lung carcinoma in mice. Methods: Kinetic changes in morphology of tumor vasculature in response to recombinant human endostatin were detected under a confocal microscope with immunofluorescent staining in Lewis lung carcinomas in mice. The hypoxic cell fraction of different time was assessed with immunohistochemical staining . Effects on tumor growth were monitored as indicated in the growth curve of tumors . Results: Compared with the control group vascularity of the tumors was reduced over time by recombinant human endostatin treatment and significantly regressed for 9 days. During the treatment, pericyte coverage increased at day 3, increased markedly at day 5, and fell again at day 7. The vascular basement membrane was thin and closely associated with endothelial cells after recombinant human endostatin treatment, but appeared thickened, loosely associated with endothelial cells in control tumors. The decrease in hypoxic cell fraction at day 5 after treatment was also found. Tumor growth was not accelerated 5 days after recombinant human endostatin treatment. Conclusions: Recombinant human endostatin can normalize tumor vasculature within day 3 to 7, leading to improved tumor oxygenation. The results provide important experimental basis for combining recombinant human endostatin with radiation therapy in human tumors. (authors)

  19. Designing and Implementing an Ergonomics Inventory to Improve Management of Human Factors Programs.

    Science.gov (United States)

    Johnson, Kenneth A.

    Self-report ergometric inventories can provide valuable information to employers and can serve as a means of intervention to improve employee attributes. Based on the science of ergonomics (a science that studies the natural laws of work in order to maximize human efficiency in job performance), such an inventory focuses on the interaction of the…

  20. Ethics in action: Approving and improving medical research with human subjects

    NARCIS (Netherlands)

    de Jong, J.P.

    2013-01-01

    In this thesis, Jean Philippe de Jong presents a new understanding of ethical oversight on medical research with human subjects and proposes that two philosophies for ethical oversight exist: '(dis)approving' and 'improving'. Systems for ethical oversight on medical research have been in place for

  1. Human Albumin Fragments Nanoparticles as PTX Carrier for Improved Anti-cancer Efficacy

    Directory of Open Access Journals (Sweden)

    Liang Ge

    2018-06-01

    Full Text Available For enhanced anti-cancer performance, human serum albumin fragments (HSAFs nanoparticles (NPs were developed as paclitaxel (PTX carrier in this paper. Human albumins were broken into fragments via degradation and crosslinked by genipin to form HSAF NPs for better biocompatibility, improved PTX drug loading and sustained drug release. Compared with crosslinked human serum albumin NPs, the HSAF-NPs showed relative smaller particle size, higher drug loading, and improved sustained release. Cellular and animal results both indicated that the PTX encapsulated HSAF-NPs have shown good anti-cancer performance. And the anticancer results confirmed that NPs with fast cellular internalization showed better tumor inhibition. These findings will not only provide a safe and robust drug delivery NP platform for cancer therapy, but also offer fundamental information for the optimal design of albumin based NPs.

  2. Human Genome Epidemiology : A scientific foundation for using genetic information to improve health and prevent disease

    Directory of Open Access Journals (Sweden)

    Stefania Boccia

    2005-03-01

    Full Text Available

    Human health is determined by the interplay of genetic factors and the environment. In this context the recent advances in human genomics are expected to play a central role in medicine and public health by providing genetic information for disease prediction and prevention.

    After the completion of the human genome sequencing, a fundamental step will be represented by the translation of these discoveries into meaningful actions to improve health and prevent diseases, and the field of epidemiology plays a central role in this effort. These are some of the issues addressed by Human Genome Epidemiology –A scientific foundation for using genetic information to improve health and prevent disease, a volume edited by Prof. M. Khoury, Prof. J. Little, Prof.W. Burke and published by Oxford university Press 2004.

    This book describes the important role that epidemiological methods play in the continuum from gene discovery to the development and application of genetic tests. The Authors calls this continuum human genome epidemiology (HuGE to denote an evolving field of inquiry that uses systematic applications of epidemiological methods to assess the impact of human genetic variation on health and disease.

    The book is divided into four sections and it is structured to allow readers to proceed systematically from the fundamentals of genome technology and discovery, to the epidemiological approaches, to gene characterisation, to the evaluation of genetic tests and their use in health services and public health.

  3. Modulation of the Gastrointestinal Microbiome with Nondigestible Fermentable Carbohydrates To Improve Human Health.

    Science.gov (United States)

    Deehan, Edward C; Duar, Rebbeca M; Armet, Anissa M; Perez-Muñoz, Maria Elisa; Jin, Mingliang; Walter, Jens

    2017-09-01

    There is a clear association between the gastrointestinal (GI) microbiome and the development of chronic noncommunicable diseases, providing a rationale for the development of strategies that target the GI microbiota to improve human health. In this article, we discuss the potential of supplementing the human diet with nondigestible fermentable carbohydrates (NDFCs) to modulate the composition, structure, diversity, and metabolic potential of the GI microbiome in an attempt to prevent or treat human disease. The current concepts by which NDFCs can be administered to humans, including prebiotics, fermentable dietary fibers, and microbiota-accessible carbohydrates, as well as the mechanisms by which these carbohydrates exert their health benefits, are discussed. Epidemiological research presents compelling evidence for the health effects of NDFCs, with clinical studies providing further support for some of these benefits. However, rigorously designed human intervention studies with well-established clinical markers and microbial endpoints are still essential to establish (i) the clinical efficiency of specific NDFCs, (ii) the causal role of the GI microbiota in these effects, (iii) the underlying mechanisms involved, and (iv) the degree by which inter-individual differences between GI microbiomes influence these effects. Such studies would provide the mechanistic understanding needed for a systematic application of NDFCs to improve human health via GI microbiota modulation while also allowing the personalization of these dietary strategies.

  4. Improving human reliability through better nuclear power plant system design. Progress report

    International Nuclear Information System (INIS)

    Golay, M.W.

    1995-01-01

    The project on open-quotes Development of a Theory of the Dependence of Human Reliability upon System Designs as a Means of Improving Nuclear Power Plant Performanceclose quotes has been undertaken in order to address the important problem of human error in advanced nuclear power plant designs. Most of the creativity in formulating such concepts has focused upon improving the mechanical reliability of safety related plant systems. However, the lack of a mature theory has retarded similar progress in reducing the likely frequencies of human errors. The main design mechanism used to address this class of concerns has been to reduce or eliminate the human role in plant operations and accident response. The plan of work being pursued in this project is to perform a set of experiments involving human subject who are required to operate, diagnose and respond to changes in computer-simulated systems, relevant to those encountered in nuclear power plants. In the tests the systems are made to differ in complexity in a systematic manner. The computer program used to present the problems to be solved also records the response of the operator as it unfolds. Ultimately this computer is also to be used in compiling the results of the project. The work of this project is focused upon nuclear power plant applications. However, the persuasiveness of human errors in using all sorts of electromechanical machines gives it a much greater potential importance. Because of this we are attempting to pursue our work in a fashion permitting broad generalizations

  5. Technologies for improving current and future light water reactor operation and maintenance: Development on the basis of O and M experiences - the WANO perspective

    International Nuclear Information System (INIS)

    Chang, M.J.

    2000-01-01

    World Association of Nuclear Operators (WANO) plays a role of promoting safety and reliability to nuclear industry after Chernobyl accident. Four programmes or so called cornerstones, operating experience, peer review, professional and technical development, and technical support and exchange have significantly promoted the nuclear operating performance in the past years. A WANO biennial general meeting was recently held in Victoria, Canada, which disclosed apparent achievements on higher unit capability factor, lower unplanned automatic scram per 7000 hours critical, lower collective radiation exposure and lower industrial safety accident rate. In more practical, exchange visits to learn good practices and measures in operation, maintenance, and management have shown benefits among WANO members. Recurring events can be minimized when members learn lessons from significant operating experience reports, significant event reports, and those events have posted on the WANO Web site. Particularly, plant managers' meetings that Tokyo Centre host have created an environment, which allows plant management to exchange ideas by such a face-to-face channel. WANO aims at nuclear safety and reliability. Economic and public acceptance are regarded as pillars to support WANO's mission as well. (author)

  6. A Randomized Trial Using Motivational Interviewing for Maintenance of Blood Pressure Improvements in a Community-Engaged Lifestyle Intervention: HUB City Steps

    Science.gov (United States)

    Landry, Alicia; Madson, Michael; Thomson, Jessica; Zoellner, Jamie; Connell, Carol; Yadrick, Kathleen

    2015-01-01

    Little is known about the effective dose of motivational interviewing for maintaining intervention-induced health outcome improvements. The purpose of this study was to compare effects of two doses of motivational interviewing for maintaining blood pressure improvements in a community-engaged lifestyle intervention conducted with…

  7. A randomized trail using motivational interviewing for maintenance of blood pressure improvements in a community-engaged lifestyle intervention: HUB City Steps

    Science.gov (United States)

    Background: Little is known about the effective dose of motivational interviewing for maintaining intervention-induced health outcome improvements. Purpose: To compare effects of two doses of motivational interviewing for maintaining blood pressure improvements in a community-engaged lifestyle int...

  8. Reliability centered maintenance streamlining through lessons learned

    International Nuclear Information System (INIS)

    Strong, D.K.

    1991-01-01

    In late 1986, PSE and G concluded that the Nuclear Department would develop a consistent approach to maintenance at Artificial Island (Salem and Hope Creak nuclear units). Preventive maintenance (PM) would be the heart of this approach. In the last six months of 1987 departments affected by the maintenance program participated on working groups that developed the Artificial Island maintenance philosophy. The central theme of the maintenance philosophy is the RCM (reliability centered maintenance) process. A pilot project tested the process in 1988. In 1989 the Central PM Group formed and in 1990 was given responsibility and authority to analyze, approve, implement, and control PM program changes. RCM is the central theme of the PM improvement effort but not the whole effort. Other important pieces included in this paper are: development of a common PM program, improvement of work instructions, development of predictive maintenance techniques into programs, development of a PM basis database, development of PM feedback from failure trends, root cause analysis, maintenance performance indicators, technicians, and engineers

  9. Random maintenance policies

    CERN Document Server

    Nakagawa, Toshio

    2014-01-01

    Exploring random maintenance models, this book provides an introduction to the implementation of random maintenance, and it is one of the first books to be written on this subject.  It aims to help readers learn new techniques for applying random policies to actual reliability models, and it provides new theoretical analyses of various models including classical replacement, preventive maintenance and inspection policies. These policies are applied to scheduling problems, backup policies of database systems, maintenance policies of cumulative damage models, and reliability of random redundant systems. Reliability theory is a major concern for engineers and managers, and in light of Japan’s recent earthquake, the reliability of large-scale systems has increased in importance. This also highlights the need for a new notion of maintenance and reliability theory, and how this can practically be applied to systems. Providing an essential guide for engineers and managers specializing in reliability maintenance a...

  10. Framework for Maintenance Planning

    DEFF Research Database (Denmark)

    Soares, C. Guedes; Duarte, J. Caldeira; Garbatov, Y.

    2010-01-01

    the design and during the whole life span of operational use, within an integrated framework founded on risk and reliability based techniques. The document addresses designers, decision makers and professionals responsible for or involved in establishing maintenance plans. The purpose of this document......The present document presents a framework for maintenance planning. Maintenance plays a fundamental role in counteracting degradation effects, which are present in all infrastructure and industrial products. Therefore, maintenance planning is a very critical aspect to consider both during...... is to present maintenance as an integrated approach that needs to be planned, designed, engineered, and controlled by proper qualitative and quantitative techniques. This document outlines the basic premises for maintenance planning and provides the general philosophies that can be followed and points to a best...

  11. Analysis of Human Errors in Industrial Incidents and Accidents for Improvement of Work Safety

    DEFF Research Database (Denmark)

    Leplat, J.; Rasmussen, Jens

    1984-01-01

    Methods for the analysis of work accidents are discussed, and a description is given of the use of a causal situation analysis in terms of a 'variation tree' in order to explain the course of events of the individual cases and to identify possible improvements. The difficulties in identifying...... 'causes' of accidents are discussed, and it is proposed to analyze accident reports with the specific aim of identifying the potential for future improvements rather than causes of past events. In contrast to traditional statistical analysis of work accident data, which typically give very general...... recommendations, the method proposed identifies very explicit countermeasures. Improvements require a change in human decisions during equipment design, work planning, or the execution itself. The use of a model of human behavior drawing a distinction between automated skill-based behavior, rule-based 'know...

  12. Improving human reliability through better nuclear power plant system design: Program for advanced nuclear power studies

    International Nuclear Information System (INIS)

    Golay, M.W.

    1993-01-01

    The project on ''Development of a Theory of the Dependence of Human Reliability upon System Designs as a Means of Improving Nuclear Power Plant Performance'' was been undertaken in order to address the problem of human error in advanced nuclear power plant designs. Lack of a mature theory has retarded progress in reducing likely frequencies of human errors. Work being pursued in this project is to perform a set of experiments involving human subjects who are required to operate, diagnose and respond to changes in computer-simulated systems, relevant to those encountered in nuclear power plants, which are made to differ in complexity in a systematic manner. The computer program used to present the problems to be solved also records the response of the operator as it unfolds

  13. Software evolution and maintenance

    CERN Document Server

    Tripathy, Priyadarshi

    2014-01-01

    Software Evolution and Maintenance: A Practitioner's Approach is an accessible textbook for students and professionals, which collates the advances in software development and provides the most current models and techniques in maintenance.Explains two maintenance standards: IEEE/EIA 1219 and ISO/IEC14764Discusses several commercial reverse and domain engineering toolkitsSlides for instructors are available onlineInformation is based on the IEEE SWEBOK (Software Engineering Body of Knowledge)

  14. Status of fusion maintenance

    International Nuclear Information System (INIS)

    Fuller, G.M.

    1984-01-01

    Effective maintenance will be an essential ingredient in determining fusion system productivity. This level of productivity will result only after close attention is paid to the entire system as an entity and appropriate integration of the elements is made. The status of fusion maintenance is reviewed in the context of the entire system. While there are many challenging developmental tasks ahead in fusion maintenance, the required technologies are available in several high-technology industries, including nuclear fission

  15. Laboratory equipment maintenance contracts.

    Science.gov (United States)

    Boudreau, D A; Scheer, W D; Catrou, P G

    1985-12-01

    The increasing level of technical sophistication and complexity found in clinical laboratory instrumentation today more than ever demands careful attention to maintenance service needs. The time-worn caution for careful definition of requirements for acquisition of a system should also carry over to acquisition of maintenance service. Guidelines are presented for specifications of terms and conditions for maintenance service from the perspective of the laboratorian in the automated clinical laboratory.

  16. Interactive videodisc in maintenance

    International Nuclear Information System (INIS)

    Zwingelstein, G.; Nguyen Van Nghi, B.

    1986-01-01

    After a recall of the videodisc characteristics, this paper presents its utilization by Electricite de France in the framework of training and maintenance. The SICMA (Interactive Communication System in Maintenance) developed and tested by Electricte de France is presented as also its utilization. It has been tested on the sites of Dampierre and Paluel in the cases of training and maintenance (deconnexion of drive rods of control elements); the conclusions of this experimentation are finally given. 4 refs [fr

  17. Human growth hormone stabilizes walking and improves strength in a patient with dominantly inherited calpainopathy

    DEFF Research Database (Denmark)

    Prahm, Kira Philipsen; Feldt-Rasmussen, Ulla; Vissing, John

    2017-01-01

    The aim was to investigate if daily low-dose treatment with recombinant human growth hormone (somatropine) can stabilize or improve muscle strength and walking capability in a patient with dominantly inherited calpainopathy. The patient was treated with daily injections of somatropine, except...... for a 6-month pause, over a period of 4.5 years. Efficacy was assessed by repeated muscle dynamometry tests and 6-minute walk tests (6MWT). Strength improved in most muscle groups on treatment, deteriorated in the 6-month off treatment, and improved again when treatment was resumed. The 6MWT stabilized...... during the initial 18-month treatment period, then deteriorated in the 6 months off treatment and improved to pre-trial levels when treatment was resumed. The findings suggest that supplementation with somatropine, within physiological ranges, may improve muscle strength and stabilize walking capability...

  18. Incentives for improving human resource outcomes in health care: overview of reviews.

    Science.gov (United States)

    Misfeldt, Renee; Linder, Jordana; Lait, Jana; Hepp, Shelanne; Armitage, Gail; Jackson, Karen; Suter, Esther

    2014-01-01

    To review the effectiveness of financial and nonfinancial incentives for improving the benefits (recruitment, retention, job satisfaction, absenteeism, turnover, intent to leave) of human resource strategies in health care. Overview of 33 reviews published from 2000 to 2012 summarized the effectiveness of incentives for improving human resource outcomes in health care (such as job satisfaction, turnover rates, recruitment, and retention) that met the inclusion criteria and were assessed by at least two research members using the Assessment of Multiple Systematic Reviews quality assessment tool. Of those, 13 reviews met the quality criteria and were included in the overview. Information was extracted on a description of the review, the incentives considered, and their impact on human resource outcomes. The information on the relationship between incentives and outcomes was assessed and synthesized. While financial compensation is the best-recognized approach within an incentives package, there is evidence that health care practitioners respond positively to incentives linked to the quality of the working environments including opportunities for professional development, improved work life balance, interprofessional collaboration, and professional autonomy. There is less evidence that workload factors such as job demand, restructured staffing models, re-engineered work designs, ward practices, employment status, or staff skill mix have an impact on human resource outcomes. Overall, evidence of effective strategies for improving outcomes is mixed. While financial incentives play a key role in enhancing outcomes, they need to be considered as only one strategy within an incentives package. There is stronger evidence that improving the work place environment and instituting mechanisms for work-life balance need to be part of an overall strategy to improve outcomes for health care practitioners.

  19. Industrial Maintenance Strategies

    International Nuclear Information System (INIS)

    Sajjad Akbar

    2006-01-01

    Industrial plants have become more complex due to technological advancement. This has made the task of maintenance more difficult. The maintenance costs in terms of resources and downtime loss are so high that maintenance function has become a critical factor in a plant's profitability. Industry should devote as much forethought to the management of maintenance function as to production. Maintenance has grown from an art to a precise, technical engineering science. Planning, organizing scheduling and control of maintenance using modern techniques pays dividends in the form of reduced costs and increased reliability. The magnitude and the dimension of maintenance have multiplied due to development in the engineering technologies. Production cost and capacities are directly affected by the breakdown time. Total operating cost including the maintenance cost plays an important role in replacement dimension. The integrated system approach would bring forth the desired results of high maintenance standards. The standards once achieved and sustained, would add to the reliability of the plan and relieve heavy stresses and strains on the engineering logistic support. (author)

  20. Analysis of maintenance strategies

    International Nuclear Information System (INIS)

    Laakso, K.; Simola, K.

    1998-01-01

    The main topics of the presentation include: (1) an analysis model and methods to evaluate maintenance action programs and the support decision to make changes in them and (2) to understand the maintenance strategies in a systems perspective as a basis for future developments. The subproject showed how systematic models for maintenance analysis and decision support, utilising computerised and statistical tool packages, can be taken into use for evaluation and optimisation of maintenance of active systems from the safety and economic point of view