WorldWideScience

Sample records for main factor controlling

  1. Evaluation of human factors in interface design in main control rooms

    International Nuclear Information System (INIS)

    Hwang, S.-L.; Liang, S.-F.M.; Liu, T.-Y.Y.; Yang, Y.-J.; Chen, P.-Y.; Chuang, C.-F.

    2009-01-01

    An evaluation of human factors in a new nuclear power plant was conducted prior to the beginning of any business operations. After the task analysis and observation of training, two stages of interviews were carried out with the operators in the Fourth Nuclear Power Plant (NPP4). The main concerns identified were problems resulting from the operating interface of the display and controls in the main control room, usability of procedures, and the layout of the main control room. The latent human errors and suggestions were listed, and the top three problems were analyzed. The operators indicated that the alarm design issues and the critical problem of the operating mode with the VDU were worth further study in order to provide suggestions for a new interface design for future power plants.

  2. Psychological factors of professional success of nuclear power plant main control room operators

    Directory of Open Access Journals (Sweden)

    Kosenkov A.A.

    2014-12-01

    Full Text Available Aim: to conduct a comparative analysis of the psychological characteristics of the most and least successful main control room operators. Material and Methods. Two NPP staff groups: the most and least successful main control room operators, who worked in routine operating conditions, were surveyed. Expert evaluation method has been applied to identify the groups. The subjects were administered the Minnesota Multiphasic Personality Inventory (MMPI, Cattell's Sixteen Personality Factor Questionnaire (16PF form A and Raven's Progressive Matrices test. Results. Numerous significant psychological differences between the groups of most and least successful control room operators were obtained: the best operators were significantly more introverted and correctly solved more logical tasks with smaller percentage of mistakes under time pressure than worst ones. Conclusions: 1. The psychodiagnostic methods used in the study were adequate to meet research objective 2. Tendency to introversion, as well as developed the ability to solve logic problems undertime pressure, apparently, are important professional qualities for control room operators. These indicators should be considered in the process of psychological selection and professional guidance of nuclear power plant operators.

  3. Research on cognitive reliability model for main control room considering human factors in nuclear power plants

    International Nuclear Information System (INIS)

    Jiang Jianjun; Zhang Li; Wang Yiqun; Zhang Kun; Peng Yuyuan; Zhou Cheng

    2012-01-01

    Facing the shortcomings of the traditional cognitive factors and cognitive model, this paper presents a Bayesian networks cognitive reliability model by taking the main control room as a reference background and human factors as the key points. The model mainly analyzes the cognitive reliability affected by the human factors, and for the cognitive node and influence factors corresponding to cognitive node, a series of methods and function formulas to compute the node cognitive reliability is proposed. The model and corresponding methods can be applied to the evaluation of cognitive process for the nuclear power plant operators and have a certain significance for the prevention of safety accidents in nuclear power plants. (authors)

  4. Nuclear power station main control room habitability

    International Nuclear Information System (INIS)

    Paschal, W.B.; Knous, W.S.

    1989-01-01

    The main control room at a nuclear power station must remain habitable during a variety of plant conditions and postulated events. The control room habitability requirement and the function of the heating, ventilating, air-conditioning, and air treatment system are to control environmental factors, such as temperature, pressure, humidity, radiation, and toxic gas. Habitability requirements provide for the safety of personnel and enable operation of equipment required to function in the main control room. Habitability as an issue has been gaining prominence with the Advisor Committee of Reactor Safeguards and the Nuclear Regulatory Commission since the incident at Three Mile Island. Their concern is the ability of the presently installed habitability systems to control the main control room environment after an accident. This paper discusses main control room HVAC systems; the concern, requirements, and results of NRC surveys and notices; and an approach to control room habitability reviews

  5. Analysis of Human Error Types and Performance Shaping Factors in the Next Generation Main Control Room

    International Nuclear Information System (INIS)

    Sin, Y. C.; Jung, Y. S.; Kim, K. H.; Kim, J. H.

    2008-04-01

    Main control room of nuclear power plants has been computerized and digitalized in new and modernized plants, as information and digital technologies make great progresses and become mature. Survey on human factors engineering issues in advanced MCRs: Model-based approach, Literature survey-based approach. Analysis of human error types and performance shaping factors is analysis of three human errors. The results of project can be used for task analysis, evaluation of human error probabilities, and analysis of performance shaping factors in the HRA analysis

  6. Fresh chicken as main risk factor for campylobacteriosis, Denmark

    DEFF Research Database (Denmark)

    Wingstrand, Anne; Neimann, Jakob; Engberg, Jørgen

    2006-01-01

    We report the findings of a case-control study of risk factors for sporadic cases of human campylobacteriosis in Denmark. In 3 different analytical models, the main domestic risk factor identified was eating fresh, unfrozen chicken. Specifically, 28 of 74 domestically acquired case-patients were...... exposed to fresh chicken compared with 21 of 114 controls (multivariate matched odds ratio 5.8; 95% confidence interval 2.1-15.9). In contrast, a risk from eating other poultry, including previously frozen chicken, was only indicated from borderline significant 2-factor interactions. The marked increase...

  7. Fresh Chicken as Main Risk Factor for Campylobacteriosis, Denmark

    OpenAIRE

    Wingstrand, Anne; Neimann, Jakob; Engberg, Jørgen; Nielsen, Eva Møller; Gerner-Smidt, Peter; Wegener, Henrik C.; Mølbak, Kåre

    2006-01-01

    We report the findings of a case-control study of risk factors for sporadic cases of human campylobacteriosis in Denmark. In 3 different analytical models, the main domestic risk factor identified was eating fresh, unfrozen chicken. Specifically, 28 of 74 domestically acquired case-patients were exposed to fresh chicken compared with 21 of 114 controls (multivariate matched odds ratio 5.8; 95% confidence interval 2.1–15.9). In contrast, a risk from eating other poultry, including previously f...

  8. ANS main control complex three-dimensional computer model development

    International Nuclear Information System (INIS)

    Cleaves, J.E.; Fletcher, W.M.

    1993-01-01

    A three-dimensional (3-D) computer model of the Advanced Neutron Source (ANS) main control complex is being developed. The main control complex includes the main control room, the technical support center, the materials irradiation control room, computer equipment rooms, communications equipment rooms, cable-spreading rooms, and some support offices and breakroom facilities. The model will be used to provide facility designers and operations personnel with capabilities for fit-up/interference analysis, visual ''walk-throughs'' for optimizing maintain-ability, and human factors and operability analyses. It will be used to determine performance design characteristics, to generate construction drawings, and to integrate control room layout, equipment mounting, grounding equipment, electrical cabling, and utility services into ANS building designs. This paper describes the development of the initial phase of the 3-D computer model for the ANS main control complex and plans for its development and use

  9. Sedimentary facies and lithologic characters as main factors controlling hydrocarbon accumulations and their critical conditions

    Directory of Open Access Journals (Sweden)

    Jun-Qing Chen

    2015-10-01

    Full Text Available Taking more than 1000 clastic hydrocarbon reservoirs of Bohai Bay Basin, Tarim Basin and Junggar Basin, China as examples, the paper has studied the main controlling factors of hydrocarbon reservoirs and their critical conditions to reveal the hydrocarbon distribution and to optimize the search for favorable targets. The results indicated that the various sedimentary facies and lithologic characters control the critical conditions of hydrocarbon accumulations, which shows that hydrocarbon is distributed mainly in sedimentary facies formed under conditions of a long-lived and relatively strong hydrodynamic environment; 95% of the hydrocarbon reservoirs and reserves in the three basins is distributed in siltstones, fine sandstones, lithified gravels and pebble-bearing sandstones; moreover, the probability of discovering conventional hydrocarbon reservoirs decreases with the grain size of the clastic rock. The main reason is that the low relative porosity and permeability of fine-grained reservoirs lead to small differences in capillary force compared with surrounding rocks small and insufficiency of dynamic force for hydrocarbon accumulation; the critical condition for hydrocarbon entering reservoir is that the interfacial potential in the surrounding rock (Φn must be more than twice of that in the reservoir (Φs; the probability of hydrocarbon reservoirs distribution decreases in cases where the hydrodynamic force is too high or too low and when the rocks have too coarse or too fine grains.

  10. A new Main Control Room for the AGS complex

    International Nuclear Information System (INIS)

    Ingrassia, P.F.; Zaharatos, R.M.; Dyling, O.H.

    1991-01-01

    A new Main Control Room (MCR) has been built to control the accelerators of the AGS Complex. A new physical environment was produced to better control light, sound, temperature, and traffic. New control consoles were built around the work-stations that make up the distributed control system. Equipment placement within consoles and console placement within the room reflect attention to the 'human factors' needs of the operator

  11. Study on the task categorization of main control room in NPP

    International Nuclear Information System (INIS)

    Fang Zhou; Ma Zhicai; Ma Xusheng; Zheng Mingguang

    2005-01-01

    The paper states the importance and trendy requirements of Main Control Room (MCR) in nuclear power plant and introduces how to implement the human factor engineering principle in the design of advanced main control room. It mainly focuses on the purpose and functions, strategy and methodology, scope and contents of the MCR task categorization. The preliminary MCR task categorization is performed according to these principles. (authors)

  12. A new main control room for the AGS complex

    International Nuclear Information System (INIS)

    Ingrassia, P.F.; Zaharatos, R.M.; Dyling, O.H.

    1991-01-01

    A new Main Control Room (MCR) has been built to control the accelerators of the AGS Complex. A new physical environment was produced to better control light, sound, temperature, and traffic. New control consoles were built around the work-stations that make up the distributed control system. Equipment placement within consoles and console placement within the room reflect attention to the ''human factors'' needs of the operator. 1 ref., 2 figs

  13. The advanced main control console for next japanese PWR plants

    International Nuclear Information System (INIS)

    Tsuchiya, A.; Ito, K.; Yokoyama, M.

    2001-01-01

    The purpose of the improvement of main control room designing in a nuclear power plant is to reduce operators' workload and potential human errors by offering a better working environment where operators can maximize their abilities. In order to satisfy such requirements, the design of main control board applied to Japanese Pressurized Water Reactor (PWR) type nuclear power plant has been continuously modified and improved. the Japanese Pressurized Water Reactor (PWR) Utilities (Electric Power Companies) and Mitsubishi Group have developed an advanced main control board (console) reflecting on the study of human factors, as well as using a state of the art electronics technology. In this report, we would like to introduce the configuration and features of the Advanced Main Control Console for the practical application to the next generation PWR type nuclear power plants including TOMARI No.3 Unit of Hokkaido Electric Power Co., Inc. (author)

  14. New Main Ring control system

    International Nuclear Information System (INIS)

    Seino, K.; Anderson, L.; Ducar, R.; Franck, A.; Gomilar, J.; Hendricks, B.; Smedinghoff, J.

    1990-03-01

    The Fermilab Main Ring control system has been operational for over sixteen years. Aging and obsolescence of the equipment make the maintenance difficult. Since the advent of the Tevatron, considerable upgrades have been made to the controls of all the Fermilab accelerators except the Main Ring. Modernization of the equipment and standardization of the hardware and software have thus become inevitable. The Tevatron CAMAC serial system has been chosen as a basic foundation in order to make the Main Ring control system compatible with the rest of the accelerator complex. New hardware pieces including intelligent CAMAC modules have been designed to satisfy unique requirements. Fiber optic cable and repeaters have been installed in order to accommodate new channel requirements onto the already saturated communication medium system. 8 refs., 2 figs

  15. 30 CFR 57.8519 - Underground main fan controls.

    Science.gov (United States)

    2010-07-01

    ... 30 Mineral Resources 1 2010-07-01 2010-07-01 false Underground main fan controls. 57.8519 Section... Ventilation Surface and Underground § 57.8519 Underground main fan controls. All underground main fans shall have controls placed at a suitable protected location remote from the fan and preferably on the surface...

  16. 14 CFR 23.527 - Hull and main float load factors.

    Science.gov (United States)

    2010-01-01

    ... 14 Aeronautics and Space 1 2010-01-01 2010-01-01 false Hull and main float load factors. 23.527... Water Loads § 23.527 Hull and main float load factors. (a) Water reaction load factors nw must be...=seaplane landing weight in pounds. (6) K1=empirical hull station weighing factor, in accordance with figure...

  17. Spatial variability and its main controlling factors of the permafrost soil-moisture on the northern-slope of Bayan Har Mountains in Qinghai-Tibet Plateau

    Science.gov (United States)

    Cao, W.; Sheng, Y.

    2017-12-01

    The soil moisture movement is an important carrier of material cycle and energy flow among the various geo-spheres in the cold regions. It is very critical to protect the alpine ecology and hydrologic cycle in Qinghai-Tibet Plateau. Especially, it becomes one of the key problems to reveal the spatial-temporal variability of soil moisture movement and its main influence factors in earth system science. Thus, this research takes the north slope of Bayan Har Mountains in Qinghai-Tibet Plateau as a case study. The present study firstly investigates the change of permafrost moisture in different slope positions and depths. Based on this investigation, this article attempts to investigate the spatial variability of permafrost moisture and identifies the key influence factors in different terrain conditions. The method of classification and regression tree (CART) is adopted to identify the main controlling factors influencing the soil moisture movement. And the relationships between soil moisture and environmental factors are revealed by the use of the method of canonical correspondence analysis (CCA). The results show that: 1) the change of the soil moisture on the permafrost slope is divided into 4 stages, including the freezing stability phase, the rapid thawing phase, the thawing stability phase and the fast freezing phase; 2) this greatly enhances the horizontal flow in the freezing period due to the terrain slope and the freezing-thawing process. Vertical migration is the mainly form of the soil moisture movement. It leads to that the soil-moisture content in the up-slope is higher than that in the down-slope. On the contrary, the soil-moisture content in the up-slope is lower than that in the down-slope during the melting period; 3) the main environmental factors which affect the slope-permafrost soil-moisture are elevation, soil texture, soil temperature and vegetation coverage. But there are differences in the impact factors of the soil moisture in different

  18. 14 CFR 25.527 - Hull and main float load factors.

    Science.gov (United States)

    2010-01-01

    ... 14 Aeronautics and Space 1 2010-01-01 2010-01-01 false Hull and main float load factors. 25.527... AIRCRAFT AIRWORTHINESS STANDARDS: TRANSPORT CATEGORY AIRPLANES Structure Water Loads § 25.527 Hull and main... 1=empirical hull station weighing factor, in accordance with figure 2 of appendix B. (7) r x=ratio...

  19. Alarm system for ABWR main control panels

    Energy Technology Data Exchange (ETDEWEB)

    Kobayashi, Yuji; Saito, Koji [Toshiba Corp., Yokohoma (Japan)

    1997-09-01

    TOSHIBA has developed integrated digital control and instrumentation system for ABWR, which is the third-generation man machine interface system for main control room that we call A-PODIA (Advanced PODIA). A-Podia has been introduced the first actual ABWR plant in Japan. in A-PODIA, TOSHIBA has realized improvement of alarm system that all operator crews in the control room can recognize plant anomalies easily. The alarm system can recognize essential alarms for plant safety easily and understand annunciators with each integrated annunciators and their prioritized color easily by classifying alarms into plant-level essential annunciators, system-level integrated annunciators and equipment level individual annunciators with hierarchical structure. This paper describes conventional alarm system and the design philosophy, alarm system design and operation of ``Alarm System for ABWR Main Control Panels``. (author). 5 refs, 8 figs, 1 tab.

  20. Alarm system for ABWR main control panels

    International Nuclear Information System (INIS)

    Kobayashi, Yuji; Saito, Koji

    1997-01-01

    TOSHIBA has developed integrated digital control and instrumentation system for ABWR, which is the third-generation man machine interface system for main control room that we call A-PODIA (Advanced PODIA). A-Podia has been introduced the first actual ABWR plant in Japan. in A-PODIA, TOSHIBA has realized improvement of alarm system that all operator crews in the control room can recognize plant anomalies easily. The alarm system can recognize essential alarms for plant safety easily and understand annunciators with each integrated annunciators and their prioritized color easily by classifying alarms into plant-level essential annunciators, system-level integrated annunciators and equipment level individual annunciators with hierarchical structure. This paper describes conventional alarm system and the design philosophy, alarm system design and operation of ''Alarm System for ABWR Main Control Panels''. (author). 5 refs, 8 figs, 1 tab

  1. Improvement of main control room

    International Nuclear Information System (INIS)

    Chae, Sung Ki; Ham, Chang Sik; Kwon, Ki Chun

    1991-07-01

    Information display system, advanced alarm system and fiber optical communication system were developed to improve the main control room in nuclear power plant. Establishing the new hierachical information structure of plant operation data, plant overview status board(POSB) and digital indicator(DI) were designed and manufactured. The prototype advanced alarm system which employed the new alarm logics and algorithm compared with the conventional alarm system were developed and its effectiveness was proved. Optical communication system which has multi-drop feature and capability of upgrading to large-scale system by using BITBUS communication protocol which is proven technology, were developed. Reliability of that system was enhanced by using distributed control. (Author)

  2. At ISR Main Control Room

    CERN Multimedia

    1983-01-01

    After 13 years the exploitation of the Intersecting Storage Rings as a beam-beam collider went to an end. In this last year the demands were very exacting, both in terms of operating time and diversified running conditions (Annual Report 1983 p. 123). Before dismantelement the photographer made a last tour, see photos 8310889X --> 8310667X. This photo shows the Main Control Room.

  3. PMBLDC motor drive with power factor correction controller

    DEFF Research Database (Denmark)

    George, G.J.; Ramachandran, Rakesh; Arun, N.

    2012-01-01

    reliability, and low maintenance requirements. The proposed Power Factor Controller topology improves power quality by improving performance of PMBLDCM drive, such as reduction of AC main current harmonics, near unity power factor. PFC converter forces the drive to draw sinusoidal supply current in phase...

  4. Influence factors analysis of water environmental quality of main rivers in Tianjin

    Science.gov (United States)

    Li, Ran; Bao, Jingling; Zou, Di; Shi, Fang

    2018-01-01

    According to the evaluation results of the water environment quality of main rivers in Tianjin in 1986-2015, this paper analyzed the current situation of water environmental quality of main rivers in Tianjin retrospectively, established the index system and multiple factors analysis through selecting factors influencing the water environmental quality of main rivers from the economy, industry and nature aspects with the combination method of principal component analysis and linear regression. The results showed that water consumption, sewage discharge and water resources were the main factors influencing the pollution of main rivers. Therefore, optimizing the utilization of water resources, improving utilization efficiency and reducing effluent discharge are important measures to reduce the pollution of surface water environment.

  5. The Main Suppressing Factors of Dry Forage Intake in Large-type Goats

    Directory of Open Access Journals (Sweden)

    Tran Van Thang

    2012-03-01

    Full Text Available In large-type goats that were fed on dry forage twice daily, dry forage intake was markedly suppressed after 40 min of feeding had elapsed. The objective of this study was to determine whether or not marked decreases in dry forage intake after 40 min of feeding are mainly caused by the two factors, that is, ruminal distension and increased plasma osmolality induced thirst produced by dry forage feeding. Six large-type male esophageal- and ruminal-fistulated goats (crossbred Japanese Saanen/Nubian, aged 2 to 6 years, weighing 85.1±4.89 kg were used in two experiments. The animals were fed ad libitum a diet of roughly crushed alfalfa hay cubes for 2 h from 10:00 to 12:00 am during two experiments. Water was withheld during feeding in both experiments but was available for a period of 30 min after completion of the 2 h feeding period. In experiment 1, saliva lost via the esophageal fistula was replenished by an intraruminal infusion of artificial parotid saliva (RIAPS in sham feeding conditions (SFC control, and the treatment was maintained under normal feeding conditions (NFC. In experiment 2, a RIAPS and non-insertion of a balloon (RIAPS-NB control was conducted in the same manner as the SFC control of experiment 1. The intraruminal infusion of hypertonic solution and insertion of a balloon (RIHS-IB treatment was carried out simultaneously to reproduce the effects of changing salt content and ruminal distension due to feed entering the rumen. The results of experiment 1 showed that due to the effects of multiple dry forage suppressing factors when feed boluses entered the rumen, eating rates in the NFC treatment decreased (p<0.05 after 40 min of feeding and cumulative dry forage intake for the 2 h feeding period reduced to 43.8% of the SFC control (p<0.01. The results of experiment 2 indicated that due to the two suppressing factors of ruminal distension and increased plasma osmolality induced thirst, eating rates in the RIHS-IB treatment were

  6. Operation Aspect of the Main Control Room of NPP

    International Nuclear Information System (INIS)

    Sahala M Lumbanraja

    2009-01-01

    The main control room of Nuclear Power Plant (NPP) is operational centre to control all of the operation activity of NPP. NPP must be operated carefully and safely. Many aspect that contributed to operation of NPP, such as man power whose operated, technology type used, ergonomic of main control room, operational management, etc. The disturbances of communication in control room must be anticipated so the high availability of NPP can be achieved. The ergonomic of the NPP control room that will be used in Indonesia must be designed suitable to anthropometric of Indonesia society. (author)

  7. Main factors in E-Learning for the Equivalency Education Program (E-LEEP)

    Science.gov (United States)

    Yel, M. B.; Sfenrianto

    2018-03-01

    There is a tremendous learning gap between formal education and non-formal education. E-Learning can facilitate non-formal education learners in improving the learning process. In this study, we present the main factors behind the E-learning for the Equivalency Education Program (E-LEEP) initiative in Indonesia. There are four main factors proposed, namely: standardization, learning materials, learning process, and learners’ characteristics. Each factor supports each other to achieve the learning process of E-LEEP in Indonesia. Although not yet proven, the E-learning should be developed followed the main factors for the non-formal education. This is because those factors can improve the quality of E-Learning for the Equivalency Education Program.

  8. Taking account of human factors in control-room design

    International Nuclear Information System (INIS)

    Dien, Y.; Montmayeul, R.

    1995-07-01

    Since the Three Mile Island accident two ways for improving the Human-Machine Interface have mainly been followed: the development of computerized operator aids in existing control-rooms and the design of advanced control-rooms. Insufficient attention paid to human factors in the design of operator aids has generally led to these aids being neglected or unused by their potential users. While for the design of advanced control-rooms efforts have been made for dealing with human factors in more extensive way. Based upon this experience, a general method for taking account of human factors in a control-room design has been devised and is described in this paper. (author)

  9. Two-Level Designs to Estimate All Main Effects and Two-Factor Interactions

    NARCIS (Netherlands)

    Eendebak, P.T.; Schoen, E.D.

    2017-01-01

    We study the design of two-level experiments with N runs and n factors large enough to estimate the interaction model, which contains all the main effects and all the two-factor interactions. Yet, an effect hierarchy assumption suggests that main effect estimation should be given more prominence

  10. Concept of Advanced Back-up Control Panel Design of Digital Main Control Room

    International Nuclear Information System (INIS)

    Jiang, Guo Jin; Sun, Yong Bin; Tan, Ke; Zhang, Li Ming; Shi, Ji; Zhang, Xue Gang; Huang, Wei Jun; Mao, Ting; Liu Yanzi

    2011-01-01

    Back-up control panel (BCP) of digital main control room (DMCR) is the backup means for main computerized control means (MCM). This paper focus on technical issues for advanced design of Backup Panel (BCP) for CPR1000 using qualified computer-based video display unit to display plant process indication and alarms. HFE issues also have been considered in the BCP design. Then, mean to fulfill safety target of NPP, best ergonomic effect has been described. At last conclusion on advanced BCP design is provided

  11. Concept of Advanced Back-up Control Panel Design of Digital Main Control Room

    Energy Technology Data Exchange (ETDEWEB)

    Jiang, Guo Jin; Sun, Yong Bin; Tan, Ke; Zhang, Li Ming; Shi, Ji; Zhang, Xue Gang; Huang, Wei Jun; Mao, Ting; Liu Yanzi [China Nuclear Power Engineering Company, Shenzen (China)

    2011-08-15

    Back-up control panel (BCP) of digital main control room (DMCR) is the backup means for main computerized control means (MCM). This paper focus on technical issues for advanced design of Backup Panel (BCP) for CPR1000 using qualified computer-based video display unit to display plant process indication and alarms. HFE issues also have been considered in the BCP design. Then, mean to fulfill safety target of NPP, best ergonomic effect has been described. At last conclusion on advanced BCP design is provided.

  12. Main factors controlling the sedimentation of high-quality shale in the Wufeng–Longmaxi Fm, Upper Yangtze region

    Directory of Open Access Journals (Sweden)

    Yuman Wang

    2017-09-01

    Full Text Available In this paper, the shale of Upper Ordovician Wufeng Fm–Lower Silurian Longmaxi Fm was taken as an example to reveal the distribution patterns and the main sedimentation controlling factors of high-quality shale in the Upper Yangtze region. This study was made from the aspects of plate movement, fluctuation of sea level, palaeo-productivity, deposition rate and paleogeographic environment, based on the field outcrop sections and drilling data of the southern Sichuan Basin, together with geochemical element testing and biostratigraphical analysis results. The following findings were obtained. First, the collision and joint of Yangtze Plate and its periphery plates and the intra-plate deformation were gentle in the early stage, strong in the late stage, gentle in northwest and strong in southeast, so the sedimentation center in the Upper Yangtze region migrated to the northwest and the closure of sea area in the southern Sichuan Basin changed from weak in early stages to strong in late stages. Second, at the turning period from Ordovician to Silurian, sea levels presented the cycle change of deep–shallow–deep–shallow. Due to the combination of high sea levels and a stable ocean basin in early stages, an extensive anoxic tectonic sedimentary space favorable for organic matters preservation was formed in the sea floor. Third, due to the effect of tectonic movements and sea closure, palaeo-productivity of sea areas in the southern Sichuan Basin presented a trend of being high in the early stage and low in the late stage, and the deposition rate was also low in the early stage and high in the late stage. And fourth, extensive deposition and distribution of shale rich in organic matters and silica was mainly controlled by a stable sea basin with a low subsidence rate, a relatively high sea level, semi-closed waters and low deposition rates. To sum up, the high-quality shale in the Upper Yangtze region is characterized by multiphase

  13. Evaluate Influence to Space Lighting Intensity in Main Control Room of RSG-GAS

    International Nuclear Information System (INIS)

    Teguh-Sulistyo; Yuyut-S-M; Yahya; Adin S

    2006-01-01

    Have been done by an activity evaluate factor depreciation influence to light source in Main Control Room (RKU). This Factor Depreciation is resulted from by defilement of effect of dirt, duration of light source utilized, way of installation, and others. Method used by perceives directly at light source, determining measurement dot in space RKU, measurement by using meter lux equipment and group storey; level depreciation of light source become light depreciation, and heavy. Than measurement result that lighting intensity in space RKU experience of decrease of equal to 1.5 %. After by stage; steps overcome the factor depreciation, result of measurement repeat obtained by decrease of equal to 0.87 %. Thereby the lighting intensity in space RKU becomes better. (author)

  14. OVERVIEW OF A RECONFIGURABLE SIMULATOR FOR MAIN CONTROL ROOM UPGRADES IN NUCLEAR POWER PLANTS

    Energy Technology Data Exchange (ETDEWEB)

    Ronald L. Boring

    2012-10-01

    This paper provides background on a reconfigurable control room simulator for nuclear power plants. The main control rooms in current nuclear power plants feature analog technology that is growing obsolete. The need to upgrade control rooms serves the practical need of maintainability as well as the opportunity to implement newer digital technologies with added functionality. There currently exists no dedicated research simulator for use in human factors design and evaluation activities for nuclear power plant modernization in the U.S. The new research simulator discussed in this paper provides a test bed in which operator performance on new control room concepts can be benchmarked against existing control rooms and in which new technologies can be validated for safety and usability prior to deployment.

  15. Function analysis and function assignment of NPP advanced main control room

    International Nuclear Information System (INIS)

    Zheng Mingguang; Xu Jijun

    2001-01-01

    The author addresses the requirements of function analysis and function assignment, which should be carried out in the design of main control room in nuclear power plant according to the design research of advanced main control room, then states its contents, functions, importance and necessity as well as how to implement these requirements and how to do design verification and validation in the design of advanced main control room of nuclear power plant

  16. High Precision Current Control for the LHC Main Power Converters

    CERN Document Server

    Thiesen, H; Hudson, G; King, Q; Montabonnet, V; Nisbet, D; Page, S

    2010-01-01

    Since restarting at the end of 2009, the LHC has reached a new energy record in March 2010 with the two 3.5 TeV beams. To achieve the performance required for the good functioning of the accelerator, the currents in the main circuits (Main Bends and Main Quadrupoles) must be controlled with a higher precision than ever previously requested for a particle accelerator at CERN: a few parts per million (ppm) of nominal current. This paper describes the different challenges that were overcome to achieve the required precision for the current control of the main circuits. Precision tests performed during the hardware commissioning of the LHC illustrate this paper.

  17. Ergonomic Investigation On The Layout And Design Of The Main Control Room Of (MCR)Reactor Thermalhydraulic Testing Loop

    International Nuclear Information System (INIS)

    DARLlS; WIDAGDO, SUHARYO

    2000-01-01

    Ergonomics investigation on the layout and design of the reactor thermalhydraulic testing loop main control room has been done. This reason is needed to be done as the primary step for evaluating of operator workload. The operator work load be influence on the operator performance, and finally would influencing the installation operation safety. Generally, the factors that is influencing on operator performance are the layout and design of MCR and its supporting physical environments factors for instance lighting, noising and climatic condition respectively. From investigation had been done, cod be identified that ergonomics point of view not implemented yet on the main control console design, especially on the alarm panel, and also found a little bit brightness problem. Otherwise the temperature and noise room are still in the tolerance boundary

  18. Evaluation of structural integrity and controllability of main feed water control valve for APWRS

    International Nuclear Information System (INIS)

    Koji Tachibana; Toshikazu Maeda; Hideyuki Morita; Takaharu Hiroe; Koichiro Oketani

    2005-01-01

    In Pressurized Water Reactors (PWR), the main feed water control valve always controls the mass flow rate of main feed water to maintain the water level of steam generator within the allowable range. For the main feed water control valve of PWR, we have used an air operated globe valve conventionally since it has large capacity and quick responsibility. On the Advanced Pressurized Water Reactors (APWR) system conditions, the mass flow rate of main feed water increases compared with the conventional PWR system conditions as an increase of the generating power. So, it is expected that the fluid force will increase, and it could cause critical damage on internal parts of the valve, such as plug, stem, etc. and uncontrollability of the valve. In this study, we measured the stem strain in the fluid tests using scale model and test loop under the APWR feed water flow rate conditions. The stem strain gave the stem stress and the fluid force acting on the plug surface. We evaluated the stem integrity from the stem stress and confirmed the influence which the fluid force had on the valve controllability by simulating the feed water system considering the fluid force. (authors)

  19. Enhancing training in the main control room

    International Nuclear Information System (INIS)

    McGuigan, K.; O'Leary, K.; Canavan, K.

    2004-01-01

    In 2003 Pickering B Nuclear of Ontario Power Generation installed a Desktop Simulator (DTS) in the Main Control Room (MCR) for training purposes. This paper will outline why this training enhancement was undertaken and the approach taken to secure its use in an active MCR environment while minimizing distractions to plant operations. (author)

  20. Optimization of the main control room habitability system in nuclear power plant

    International Nuclear Information System (INIS)

    Zheng Guanghui; Zhao Xinyan

    2013-01-01

    This article describes the optimization of main control room habitability system in nuclear power plant. It also describes the design shortage in terms of habitability in the main control room. Through modification and optimization, habitable conditions are met for personnel staying in the emergency area of the main control room for a period of time, with an aim to take accident intervention measures smoothly and reduce the accident loss and radioactive contamination as low as possible. (authors)

  1. The main factor affecting the competitiveness of Contractor Company

    Science.gov (United States)

    Nurisra; Malahayati, Nurul; Mahmuddin

    2018-05-01

    Contractor companies must have the competitive advantage to compete in maintaining the survival of the company. Problems arise because quite a lot of advantages can be used and these advantages must be used appropriately to produce competitiveness for the company to continue to compete and to win the competition. This study aims to determine the main factors affecting the competitiveness of medium-class contractors in Banda Aceh. Data collection was obtained through questionnaires distributed to 31 middle-class contractors in Banda Aceh. Data processing and analysis is done by using descriptive analysis. Based on the result of descriptive analysis, it can be concluded that the most important competitiveness factor with a mean score value 4.52 is the relationship, and the factor that has the highest mean score value is the relationship with the government of 4.97, while the result of the ranking analysis is obtained 25 factor that is critical to the competitiveness of medium-class contractors in Banda Aceh.

  2. Study on the green total factor productivity in main cities of China

    Directory of Open Access Journals (Sweden)

    Zhang Jiansheng

    2016-06-01

    Full Text Available The aim of this research is to investigate China’s urban green total factor productivity (TFP under the background of progressing urbanization and intensifying environmental pollution, and found out its main influencing factors. In this paper, green TFP of 285 prefecture-level cities in China from 2005 to 2012 was estimated through Malmquist productivity index. Results showed that the annual growth of green TFP in main cities in China is 3.5% and the overall growth declines gradually. Viewed from decomposition of green TFP, technical progress is the main contributor of green TFP growth. Furthermore, the northern coastal region has achieved the highest annual growth of green TFP (4.5% and the northwest region achieved the lowest growth of green TFP (1.24%, indicating the great regional differences of green TFP and economic growth quality in China. According to analysis on influencing factors of green TFP in main cities, it has been concluded that per-capita urban road area, number of Internet users, proportion of fiscal expenditures, environmental regulation level and technical input are significantly positively correlated with green TFP, while industrial structure and foreign direct investment (FDI are significantly negatively correlated. Finally, policy suggestions to improve urban green TFP in China were proposed.

  3. Experience with the TRIUMF Main Tank Vacuum Control System

    International Nuclear Information System (INIS)

    Sarkar, S.; Yandon, J.C.; Sievers, W.; Bennett, P.; Gurd, D.P.; Harmer, P.; Nelson, J.

    1993-01-01

    The TRIUMF Main Tank Vacuum Control System was upgraded in 1984. The earlier system, which consisted of a collection of hardwired relay logic boxes housed in three standard instrumentation racks, was replaced with a compact and flexible microprocessor-based control system. The user interface, previously distributed over the three racks, was consolidated into a single hardwired control and mimic panel. Since 1984, the Main Tank Vacuum System has undergone a series of changes in configuration and vacuum pumping hardware with necessary changes being implemented in the control system logic. Corresponding changes to the user interface were sometimes difficult to implement and in time exhausted the spare input/output capacity which had been built into the panel. The availability of inexpensive personal computers with adequate graphics capability and the ease of modifying, or adding to a programmable user interface precipitated the retirement of the hardwired panel and its replacement by a PC-based graphics user interface. System configuration, safety considerations, the hardware and the software implementation using the open-quote C close-quote programming language are described. The evolution of the control system and its performance, both over the years and in adapting to the vacuum system changes, are discussed

  4. Study on the main control room design for Hamaoka Unit No.5

    International Nuclear Information System (INIS)

    Tsuruta, Tadakazu; Sakamoto, Minoru; Maruyama, Tohru; Saito, Tadashi

    2000-01-01

    The main control room of nuclear power station is important to operate the power station and to promote public acceptance of nuclear power station. To enhance them, there is an idea of high ceiling control room with a gallery room located in backside middle upper floor. The control room is expected to enhance habitability and to offer visitors the fine view of the control room. In this study, psychological and physiological influence of such a high ceiling control room design on operators was investigated first. And then some human engineering requirements for desirable main control room were identified. A control room (ceiling height: about 5 meters) adequate to the requirements was designed, and finally the validity of the design was verified by means of full mockup model room tests. The results of this study are applied to the main control room design of Hamaoka Nuclear Power Station Unit No.5 (Chubu Electric Power Co., Inc.) (author)

  5. The main factors affecting somatic cell count in organic dairy farming

    Energy Technology Data Exchange (ETDEWEB)

    Orjales, I.; Lopez-Alonso, M.; Miranda, M.; Rodríguez-Bermúdez, R.; Rey-Crespo, F.; Villar, A.

    2017-07-01

    Preventive management practices are essential for maintaining acceptable udder health status, especially in organic farming, in which the use of antimicrobials is restricted. The contribution of the following factors to somatic cell count (SCC) was assessed in 788 cows from 15 organically reared herds in northern Spain: milk production, lactation number, treatments applied, selective dry cow therapy and teat dipping routines. The data were examined by linear logistic regression. Lactation number was the main factor affecting logSCC (β= 0.339, p<0.001) followed in order of importance by milk production (β= -0.205, p<0.001), use of alternative treatments (β=0.153, p<0.001), selective dry cow therapy (β=0.120, p=0.005) and teat dipping routines (β=-0.076, p=0.028). However, the model only explained 17.0% of the total variation in SCC. This variable depends on factors other than those considered here, amongst which udder infection is probably one of the most important. Nonetheless, the study findings enabled us to determine the contribution of the main management factors that should be taken into account to improve udder health status on organic farms.

  6. Main requirements and criteria for State nuclear material control and accounting

    International Nuclear Information System (INIS)

    Ryazanov, B.G.; Goryunov, V.K.; Erastov, V.V.

    1999-01-01

    The paper presents comments and substantiation of the main requirements and criteria for the State nuclear materials (NM) control and accounting system in the draft of the federal Main regulations of NM control and accounting. The State NM control and accounting system structure and design principles, the list of nuclear and special non-nuclear materials which are subject to the control and accounting, NM control and accounting principles are considered. Measurement system for the values for NM control and accounting and measurement assurance program, NM transfer procedures, physical inventory taking, closing a material balance and evaluation of inventory difference and balance closure of bulk form NM are shown. Accounting units in the inventory, the system accounting report documentation and preliminary notifications, the NM control and accounting arrangement, the federal and departmental control in the State NM control and accounting system, the State NM control and accounting system supervision and requirement to the personnel carrying out the NM control and accounting are discussed [ru

  7. Verbal Communication Quality Analysis of Human Operators in Main Control Room

    International Nuclear Information System (INIS)

    Kim, Seung Hwan; Park, Jin kyun

    2012-01-01

    Verbal communication problems have been one of the major human factors causing serious problems in many industries. The results of existing researches have revealed that keeping good communication quality is essential to ensure the safety of a large-sized and highly advanced industrial process system. Communication Quality is ensured only when both parties involved in a communication process understand and comprehend each other correctly, and it can be decided based on the correctness of the messages communicated between them. In this paper, we suggested a method to measure the quality of communication during off-normal situation in main control room of nuclear power plants. It evaluates the cosine similarity that is a measure of sentence similarity between two operators by finding the cosine of the angle between them

  8. THE MAIN SOCIAL RISK FACTORS IN THE FEMININ DELINQUENT BEHAVIOR

    Directory of Open Access Journals (Sweden)

    Mirela Cristiana NILĂ STRATONE

    2018-05-01

    Full Text Available The feminine criminality is a social phenomenon of defining importance in trying to draw the portrait of contemporary human society. What is the basic mechanism of this dimension of human behavior remains a continuing challenge for criminology researchers and beyond. The feminine offenses segment dresses a form of atypical aggressivity. This is the main reason who determine the identification, analization and explanation of the factors that influence and shapes the behavior of the woman, bringing it to the form of criminal behavior. The contradiction between femininity and criminality is outlined as an intrigue of gender stereotypes, which the researcher can not bypass. That is why patterns, items, everything on the background of social change are considered. The social change comes, in turn, with challenges both from the domestic area and from the outside of the family. In this paper we will review the main social nature factors that trigger the deviant behavior leading this to delinquency and even determining its identification with forms of delinquency. Women's evolution in time, in terms of age and social modernization, results in changes in the feminine attitude, the typical female actions, woman's personality as a mother, married couple, daughter, girlfriend, etc. The purpose of this study is to present risk factors with criminogen potential on women's behavior in society. Behavioral deviance, as a result of the multitude of bio-psychological, econ- omic, socio-cultural, political, natural factors, turns into violence, and violence tends to become an increasingly strong component of female temper. Last but not least, it is observed that the femininity itself, under the pressure of social factors, takes on new forms, dominated by aggressiveness.

  9. CHILD-PARENT VIOLENCE: MAIN CHARACTERISTICS, RISK FACTORS AND KEYS TO INTERVENTION

    Directory of Open Access Journals (Sweden)

    M. Luisa Martínez

    2015-09-01

    Full Text Available Child-parent Violence (hereinafter CPV is an increasingly evident problem in the social, health, and judicial protection systems which, however, continue to show a number of major deficiencies with respect to the main characteristics of CPV, the people involved, the underlying factors, and efficacious interventions. Nevertheless, there is a consensus regarding its devastating consequences. The present bibliographical review is focused on analysing the problem of CPV with the aim of offering useful data for future research and intervention proposals. Specifically, this paper provides a definition of CPV and its types, some data on prevalence, the main characteristics of aggressive children and abused parents, and the most important individual, family, school and community risk factors highlighted in the current scientific literature. The keys areas of intervention with this group are also presented.

  10. Risk assessment of main control board fire using fire dynamics simulator

    Energy Technology Data Exchange (ETDEWEB)

    Kang, Dae Il, E-mail: dikang@kaeri.re.kr [KAERI, 1045 Daedeokdaero, Yuseong-Gu, Daejeon 305-353 (Korea, Republic of); Kim, Kilyoo; Jang, Seung-Cheol [KAERI, 1045 Daedeokdaero, Yuseong-Gu, Daejeon 305-353 (Korea, Republic of); Yoo, Seong Yeon [Chungnam National University, 79, Daehagro, Yuseong-Gu, Daejeon (Korea, Republic of)

    2015-08-15

    Highlights: • A decision tree for evaluating the risk of a main control board (MCB) fire was proposed to systematically determine the MCB fire scenarios. • Fire simulations using fire dynamics simulator (FDS) were performed to estimate the time to MCR abandonment. • Non-propagating and propagating fire scenarios were considered for fire simulations. • The current study indicates that the quantification of the MCB fire risk should address the propagating fire and non-propagating fire scenarios if the MCB has no internal barriers between the panels. - Abstract: This paper presents the process and results of a risk assessment for a main control board (MCB) fire using fire dynamics simulator (FDS). A decision tree for evaluating the risk of a MCB fire was proposed to systematically determine the MCB fire scenarios, and fire simulations using FDS were performed to estimate the time to MCR abandonment. As a reference NPP for this study, Hanul unit 3 in Korea was selected and its core damage frequency (CDF) owing to the MCB fire was quantified. Two types of fire scenarios were considered for fire simulations: non-propagating fire scenarios occurring within a single MCB panel and propagating fire scenarios spreading from one control panel to the adjacent panels. Further, the fire scenarios were classified into fires with and without a heating, ventilation, and air conditioning system (HVACS). The fire simulation results showed that the major factor causing the MCR evacuation was the optical density irrelevant to the availability of the HVACS. The risk assessment results showed that the abandonment fire scenario risk was less than the non-abandonment fire scenario risk and the propagating fire scenario risk was greater than the non-propagating fire scenario risk.

  11. Risk assessment of main control board fire using fire dynamics simulator

    International Nuclear Information System (INIS)

    Kang, Dae Il; Kim, Kilyoo; Jang, Seung-Cheol; Yoo, Seong Yeon

    2015-01-01

    Highlights: • A decision tree for evaluating the risk of a main control board (MCB) fire was proposed to systematically determine the MCB fire scenarios. • Fire simulations using fire dynamics simulator (FDS) were performed to estimate the time to MCR abandonment. • Non-propagating and propagating fire scenarios were considered for fire simulations. • The current study indicates that the quantification of the MCB fire risk should address the propagating fire and non-propagating fire scenarios if the MCB has no internal barriers between the panels. - Abstract: This paper presents the process and results of a risk assessment for a main control board (MCB) fire using fire dynamics simulator (FDS). A decision tree for evaluating the risk of a MCB fire was proposed to systematically determine the MCB fire scenarios, and fire simulations using FDS were performed to estimate the time to MCR abandonment. As a reference NPP for this study, Hanul unit 3 in Korea was selected and its core damage frequency (CDF) owing to the MCB fire was quantified. Two types of fire scenarios were considered for fire simulations: non-propagating fire scenarios occurring within a single MCB panel and propagating fire scenarios spreading from one control panel to the adjacent panels. Further, the fire scenarios were classified into fires with and without a heating, ventilation, and air conditioning system (HVACS). The fire simulation results showed that the major factor causing the MCR evacuation was the optical density irrelevant to the availability of the HVACS. The risk assessment results showed that the abandonment fire scenario risk was less than the non-abandonment fire scenario risk and the propagating fire scenario risk was greater than the non-propagating fire scenario risk

  12. Evaluation Logic of Main Control Board Fire Risk

    Energy Technology Data Exchange (ETDEWEB)

    Kang, Dae Il; Kim, Kilyoo; Lim, Ho Gon [KAERI, Daejeon (Korea, Republic of)

    2015-05-15

    The main control board (MCB) is defined as the collection of control panels inside the main control room (MCR) of a nuclear power plant (NPP). As the MCB has the control and instrumentation circuits of redundant trains for almost all plant systems, small fires within the control panels may be detrimental to the safe shutdown capability. A big fire affecting many panels in the MCB can cause a forced MCR abandonment of the operators as well as function failures or spurious operations of the control and instrumentation-related components. If the MCR cannot be habitable, a safe shutdown from outside the MCR can be achieved and maintained at an alternate shutdown panel electrically and physically independent from the MCR. Because the MCB consist of many electrical panels, it may have internal barriers between them to prevent a fire from spreading from its origin to neighboring locations. However, most MCBs of domestic NPPs do not have internal barriers within them. If the MCB cabinets are not separated by a double wall with an air gap, the fire propagation of an MCB panel fire cannot be ruled out. Recently, Joglar et al. proposed a new evaluation logic for the MCB panel fires and mentioned that an MCB fire can be divided into propagation and non-propagating fires for abandonment and non-abandonment fire scenarios. However, they did not present the details on the fire modeling approaches and probability formulas for the fire scenarios. In this paper, a decision tree for evaluating the risk of an MCB fire is proposed to systematically determine the fire scenarios in terms of the fire modeling approaches. This paper proposed a decision tree for evaluating the risk of an MCB fire to systematically determine the fire scenarios in terms of fire modeling approaches.

  13. Mass Alarms in Main Control Room Caused Condensate on the Instrumentation and Control Cards in Turbine Building

    International Nuclear Information System (INIS)

    Goo, Cheol-Soo

    2015-01-01

    A bunch of alarms and trouble lights on the main control room simultaneously turned on during inspection and exchange of the coolers of the turbine building at pressurized water reactor of the Hanbit nuclear power plant No. 6. The main cause was condensate on instrumentation cards of plant control system (PCS) installed at enclosures in the turbine building which have MUX cabinets to transmit signals between the main control room and local equipment. To control the temperature and humidity of the MUX cabinets, two coolers of the plant chilled water system supply air to the compact enclosures at turbine building where temperature and humidity is high in the summer. It is an unusual experience that mass alarms abnormally were occurred in the main control room during normal plant operation phases. Spurious signals with unknown cause at control and instrumentation system occasionally may have an unnecessary actuation of monitoring equipment and a plant scram even. One of the main causes is humidity by a rapid temperature change of the control and instrumentation cards. Dew on the instrumentation cards could form an abnormal short circuit in printed circuit board with the compact circuits and make any malfunction of the related system. Instrumentation and control cards with integrated circuits are vulnerable to high humidity and temperature where the system is enclosed in a small housing or enclosure surrounding with hash environment such as a turbine building. It was found that there was no functional degradation of the safety systems and no outsides releases of radioactive materials by this occurrence. (author)

  14. What are the main risk factors for running-related injuries?

    Science.gov (United States)

    Saragiotto, Bruno Tirotti; Yamato, Tiê Parma; Hespanhol Junior, Luiz Carlos; Rainbow, Michael J; Davis, Irene S; Lopes, Alexandre Dias

    2014-08-01

    Despite several studies that have been conducted on running injuries, the risk factors for running-related injuries are still not clear in the literature. The aim of this study was to systematically review prospective cohort studies that investigated the risk factors for running injuries in general. We conducted electronic searches without restriction of language on EMBASE (1980 to Dec 2012), PUBMED (1946 to Dec 2012), CINAHL (1988 to Dec 2012) SPORTDiscus (1977 to Dec 2012), Latin American and Caribbean Centre on Health Sciences Information (1985 to Dec 2012) and Scientific Electronic Library Online (1998 to Dec 2012) databases, using subject headings, synonyms, relevant terms and variant spellings for each database. Only prospective cohort studies investigating the risk factors for running-related musculoskeletal injuries were included in this review. Two independent reviewers screened each article and, if they did not reach a consensus, a third reviewer decided whether or not the article should be included. Year of publication, type of runners, sample size, definition of running-related musculoskeletal injury, baseline characteristics, reported risk factors and the statistical measurement of risk or protection association were extracted from the articles. A scale adapted by the authors evaluated the risk of bias of the articles. A total of 11 articles were considered eligible in this systematic review. A total of 4,671 pooled participants were analysed and 60 different predictive factors were investigated. The main risk factor reported was previous injury (last 12 months), reported in 5 of the 8 studies that investigated previous injuries as a risk factor. Only one article met the criteria for random selection of the sample and only six articles included a follow-up of 6 months or more. There was no association between gender and running injuries in most of the studies. It is possible that eligible articles for this review were published in journals that were

  15. Tales of two self-control scales: Relations with Five-Factor and HEXACO traits

    NARCIS (Netherlands)

    de Vries, R.E.; van Gelder, J.L.

    2013-01-01

    This study compared the Five-Factor and HEXACO personality correlates of two common self-control constructs - Tangney self-control and Grasmick self-control - and their relations with delinquency. In both a student and a community sample, conscientiousness (mainly the prudence facet) was the most

  16. Safety measures for the main control board replacement project at Ikata units 1 and 2

    International Nuclear Information System (INIS)

    Hashimoto, Nozomu; Tada, Kenji

    2013-01-01

    When Units 1 and 2 of the Ikata Power Station underwent replacement of their main control boards, control cabinets, and associated equipment, it was necessary to remove all the control boards, cabinets, and cables from the control building including from the main control room. This meant the loss of operation and monitoring functions in the main control room and functions of control cabinets. To maintain the operation and monitoring functions required under plant shutdown conditions, temporary operation and monitoring equipment (i.e., temporary main control board) was installed in the temporary main control room. The advance preparations included a trial switching from the permanent to the temporary main control board to identify and address potential problems in advance. When the replacement work was underway, a work schedule sheet posted in the temporary and the permanent control rooms was used to prevent human errors caused by operators’ recognition errors. Monitoring and control signals were switched from the old boards to the temporary boards and from the temporary boards to the new boards at appropriate timings to ensure plant safety during the replacement operation. (author)

  17. RF control at transient beamloading for high-duty-factor linacs

    Energy Technology Data Exchange (ETDEWEB)

    Chernogubovsky, M.A.; Sugimoto, Masayoshi [Japan Atomic Energy Research Inst., Tokai, Ibaraki (Japan). Tokai Research Establishment

    1998-08-01

    An effective RF control with the transient beamloading is the major issue in the operation of the high-duty-factor linacs to suppress the undesirable beam loss. The RF control method is considered to obtain the control principle and the state equation, under the analysis of electrodynamical properties of the excitation in the resonator of the linac due to the transient beamloading. The concept of the directional selective coupling is applied for the RF system to define the main characteristics and to optimize the RF control parameters. (author)

  18. Development and validation process of the advanced main control board for next Japanese PWR plants

    International Nuclear Information System (INIS)

    Tani, M.; Ito, K.; Yokoyama, M.; Imase, M.; Okamoto, H.

    2000-01-01

    The purpose of main control room improvement is to reduce operator workload and potential human errors by offering a better working environment where operators can maximize their abilities. Japanese pressurized water reactor (PWR) utilities and Mitsubishi group have developed a touch -screen-based main control console (i.e. advanced main control room) the next generation PWRs to further improve the plant operability using a state of the art electronics technology. The advanced main control room consists of an operator console, a supervisor console and large display panels. The functional specifications were evaluated by utility operators using a prototype main control console connected to a plant simulator. (author)

  19. An experimental investigation on relationship between PSFs and operator performances in the digital main control room

    International Nuclear Information System (INIS)

    Park, Jooyoung; Lee, Daeil; Jung, Wondea; Kim, Jonghyun

    2017-01-01

    Highlights: • The relationship between performance shaping factors and operator performances are experimentally investigated. • The experiment includes features of digital main control room. • The result indicates that the operator’s experience level is the most effective on the performance. - Abstract: This study designs an experiment to investigate the relationship between performance shaping factors (PSFs) and operator performances. This study involves selecting three PSFs that are controllable in the experiments: (1) experience, (2) complexity, and (3) urgency. Six scenarios are developed to reflect the PSFs. The experiment involves the participation of licensed operators and the use of an APR1400 simulator. During the experiment, operator performances, such as completion time, error, secondary task, workload, and situation awareness, are measured and collected. The experimental result indicates that the operator’s experience is most effective on the overall performances. The task complexity influences the secondary tasks and situation awareness.

  20. Visual control as a key factor in a production process of a company from automotive branch

    Directory of Open Access Journals (Sweden)

    Stanisław Borkowski

    2013-04-01

    Full Text Available This article presents a theoretical basis for one type of control in enterprises – visual control. It presents the meaning of visual control in the Toyota Production System and BOST researches as a tool of measure, among other things, the importance of visual control in production companies. The level of importance of visual control usage as one of the production process elements in the analysed company was indicated. The usage of visual control is a main factor in a production process of the analyzed company, the factor which provides continuous help to employees to check whether the process differs from the standard. The characteristic progression of production process elements was indicated and the SW factor (the use of visual control took the third place, PE factor (interruption of production when it detects a problem of quality turned out to be the most important one, while the least important was the EU factor (granting power of attorney down. The main tools for this evaluation: an innovative BOST survey - Toyota's management principles in questions, in particular, the Pareto-Lorenz diagram, radar graph and series of importance as graphical interpretation tools, were used to present the importance of each factor in relation to individual assessments.

  1. MECAR (Main Ring Excitation Controller and Regulator): A real time learning regulator for the Fermilab Main Ring or the Main Injector synchrotron

    International Nuclear Information System (INIS)

    Flora, R.; Martin, K.; Moibenko, A.; Pfeffer, H.; Wolff, D.; Prieto, P.; Hays, S.

    1995-04-01

    The real time computer for controlling and regulating the FNAL Main Ring power supplies has been upgraded with a new learning control system. The learning time of the system has been reduced by an order of magnitude, mostly through the implementation of a 95 tap FIR filter in the learning algorithm. The magnet system consists of three buses, which must track each other during a ramp from 100 to 1700 amps at a 2.4 second repetition rate. This paper will present the system configuration and the tools used during development and testing

  2. Human error mode identification for NPP main control room operations using soft controls

    International Nuclear Information System (INIS)

    Lee, Seung Jun; Kim, Jaewhan; Jang, Seung-Cheol

    2011-01-01

    The operation environment of main control rooms (MCRs) in modern nuclear power plants (NPPs) has considerably changed over the years. Advanced MCRs, which have been designed by adapting digital and computer technologies, have simpler interfaces using large display panels, computerized displays, soft controls, computerized procedure systems, and so on. The actions for the NPP operations are performed using soft controls in advanced MCRs. Soft controls have different features from conventional controls. Operators need to navigate the screens to find indicators and controls and manipulate controls using a mouse, touch screens, and so on. Due to these different interfaces, different human errors should be considered in the human reliability analysis (HRA) for advanced MCRs. In this work, human errors that could occur during operation executions using soft controls were analyzed. This work classified the human errors in soft controls into six types, and the reasons that affect the occurrence of the human errors were also analyzed. (author)

  3. Reliability analysis of operator's monitoring behavior in digital main control room of nuclear power plants and its application

    International Nuclear Information System (INIS)

    Zhang Li; Hu Hong; Li Pengcheng; Jiang Jianjun; Yi Cannan; Chen Qingqing

    2015-01-01

    In order to build a quantitative model to analyze operators' monitoring behavior reliability of digital main control room of nuclear power plants, based on the analysis of the design characteristics of digital main control room of a nuclear power plant and operator's monitoring behavior, and combining with operators' monitoring behavior process, monitoring behavior reliability was divided into three parts including information transfer reliability among screens, inside-screen information sampling reliability and information detection reliability. Quantitative calculation model of information transfer reliability among screens was established based on Senders's monitoring theory; the inside screen information sampling reliability model was established based on the allocation theory of attention resources; and considering the performance shaping factor causality, a fuzzy Bayesian method was presented to quantify information detection reliability and an example of application was given. The results show that the established model of monitoring behavior reliability gives an objective description for monitoring process, which can quantify the monitoring reliability and overcome the shortcomings of traditional methods. Therefore, it provides theoretical support for operator's monitoring behavior reliability analysis in digital main control room of nuclear power plants and improves the precision of human reliability analysis. (authors)

  4. An analysis of main factors in electron beam flue gas purification

    International Nuclear Information System (INIS)

    Zhang Ming; Xu Guang

    2003-01-01

    Electron beam flue gas purification method is developing very quickly in recent years. Based on the experiment setting for electron beam flue gas purification in Institute of Nuclear Energy and Technology, Tsinghua University, how the technique factors affect the ratio of desulphurization and denitrogenation are described. Radiation dose (D), temperature (T), humidity (H), pour ammonia quantity (α) and initial concentration of SO 2 (C SO 2 ) and NO x (C NO x ) are main factors influencing flue gas purification. Using the methods of correlation analysis and regression analysis, the primary effect factors are found out and the regression equations are set to optimize the system process, predigest the system structure and to forecast the experimental results. (authors)

  5. Radial oil injection applied to main engine bearings: evaluation of injection control rules

    DEFF Research Database (Denmark)

    Estupiñan, EA; Santos, Ilmar

    2012-01-01

    , the dynamic behaviour of the main bearing of a medium-size engine is theoretically analysed when the engine operates with controllable radial oil injection and four different injection control rules. The theoretical investigation is based on a single-cylinder combustion engine model. The performance......The performance of main bearings in a combustion engine affects key functions such as durability, noise and vibration. Thus, with the aim of reducing friction losses and vibrations between the crankshaft and the bearings, the work reported here evaluates different strategies for applying...... controllable radial oil injection to main crankshaft journal bearings. In an actively lubricated bearing, conventional hydrodynamic lubrication is combined with controllable hydrostatic lubrication, where the oil injection pressures can be modified depending on the operational conditions. In this study...

  6. Robust Backstepping Control for Cold Rolling Main Drive System with Nonlinear Uncertainties

    Directory of Open Access Journals (Sweden)

    Xu Yang

    2013-01-01

    Full Text Available The nonlinear model of main drive system in cold rolling process, which considers the influence with parameter uncertainties such as clearance and variable friction coefficient, as well as external disturbance by roll eccentricity and variation of strip material quality, is built. By transformation, the lower triangular structure form of main drive system is obtained. The backstepping algorithm based on signal compensation is proposed to design a linear time-invariant (LTI robust controller, including a nominal controller and a robust compensator. A comparison with PI controller shows that the controller has better disturbance attenuation performance and tracking behaviors. Meanwhile, according to its LTI characteristic, the robust controller can be realized easily; therefore it is also appropriated to high speed dynamic rolling process.

  7. Analysis of man-machine interaction for control and display system in main control room of light water reactor

    International Nuclear Information System (INIS)

    Santosa, Kussigit; Supriatna, Piping; Karlina, Itjeu; Widagdo, Suharyo; Darlis; Sudiono, Bambang

    1998-01-01

    One of potential hazard in Nuclear Power Plant is the failure of its operation. The accident or operation failure in the reactor must be concerned event its probability is low. The important thing should be concerned is 'Analysis of Man-Machine Interaction (MMI) for Control and Display System in Main Control Room (MCR) of Nuclear Power Reactor', especially LWR type. Control and Display System in MCR of Reactor is the main part of MMI link process in Reactor MCR work system. Signal from display system showed performance process in reactor, while this signal will be received by operator. This signal will be described through central nerve for making decision what kind must be done. Then the operator manage the next process of reactor operation through control system. So by knowing Analysis of Man-Machine Interaction for Control and Display System in Main Control Room of Power Reactor, we can understand human error probability of the operator in reactor operation

  8. Emittance and trajectory control in the main linacs of the NLC

    International Nuclear Information System (INIS)

    Assmann, R.; Adolphsen, C.; Bane, K.; Raubenheimer, T.O.; Thompson, K.

    1996-09-01

    The main linacs of the next generation of linear colliders need to accelerate the particle beams to energies of up to 750 GeV while maintaining very small emittances. This paper describes the main mechanisms of static emittance growth in the main linacs of the Next Linear Collider (NLC). The authors present detailed simulations of the trajectory and emittance control algorithms that are foreseen for the NLC. They show that the emittance growth in the main linacs can be corrected down to about 110%. That number is significantly better than required for the NLC design luminosity

  9. Uncertainty analysis for parameters of CFAST in the main control room fire scenario

    Energy Technology Data Exchange (ETDEWEB)

    Wang, Wanhong; Guo, Yun; Peng, Changhong [Univ. of Science and Technology of China No. 96, Anhui (China). School of Nuclear Science and Technology

    2017-07-15

    The fire accident is one of important initial events in the nuclear power plant. Moreover, the fire development process is extremely difficult and complex to predict accurately. As a result, the plant internal fire accidents have become one of the most realistic threat on the safety of the nuclear power plants. The main control room contains all the control and monitoring equipment that operators need. Once it is on fire, hostile environments would greatly impact on the safety of human operations. Therefore, fire probability safety analysis on the main control room has become a significant task. By using CFAST and Monte Carlo sampling method as a tool for fire modeling to simulate main control room on fire, we can examine uncertainty analysis for the important parameters of CFAST.

  10. Migration of Older to New Digital Control Systems in Nuclear Power Plant Main Control Rooms

    Energy Technology Data Exchange (ETDEWEB)

    Kovesdi, Casey Robert [Idaho National Lab. (INL), Idaho Falls, ID (United States); Joe, Jeffrey Clark [Idaho National Lab. (INL), Idaho Falls, ID (United States)

    2016-04-01

    The United States (U.S.) Department of Energy (DOE) Office of Nuclear Energy (NE) has the primary mission to advance nuclear power by resolving socio-technical issues through research and development (R&D). One DOE-NE activity supporting this mission is the Light Water Reactor Sustainability (LWRS) program. LWRS has the overall objective to sustain the operation of existing commercial nuclear power plants (NPPs) through conducting R&D across multiple “pathways,” or R&D focus areas. The Advanced Instrumentation, Information, and Control (II&C) Systems Technologies pathway conducts targeted R&D to address aging and reliability concerns with the legacy instrumentation and control (I&C) and related information systems in operating U.S. NPPs. This work involves (1) ensuring that legacy analog II&C systems are not life-limiting issues for the LWR fleet, and (2) implementing digital II&C technology in a manner that enables broad innovation and business improvement in the NPP operating model. Under the LWRS Advanced II&C pathway, Human Factors experts at Idaho National Laboratory (INL) have been conducting R&D in support of NPP main control room (MCR) modernization activities. Work in prior years has focused on migrating analog I&C systems to new digital I&C systems (). In fiscal year 2016 (FY16), one new focus area for this research is migrating older digital I&C systems to new and advanced digital I&C systems. This report summarizes a plan for conducting a digital-to-digital migration of a legacy digital I&C system to a new digital I&C system in support of control room modernization activities.

  11. Migration of Older to New Digital Control Systems in Nuclear Power Plant Main Control Rooms

    International Nuclear Information System (INIS)

    Kovesdi, Casey Robert; Joe, Jeffrey Clark

    2016-01-01

    The United States (U.S.) Department of Energy (DOE) Office of Nuclear Energy (NE) has the primary mission to advance nuclear power by resolving socio-technical issues through research and development (R&D). One DOE-NE activity supporting this mission is the Light Water Reactor Sustainability (LWRS) program. LWRS has the overall objective to sustain the operation of existing commercial nuclear power plants (NPPs) through conducting R&D across multiple ''pathways,'' or R&D focus areas. The Advanced Instrumentation, Information, and Control (II&C) Systems Technologies pathway conducts targeted R&D to address aging and reliability concerns with the legacy instrumentation and control (I&C) and related information systems in operating U.S. NPPs. This work involves (1) ensuring that legacy analog II&C systems are not life-limiting issues for the LWR fleet, and (2) implementing digital II&C technology in a manner that enables broad innovation and business improvement in the NPP operating model. Under the LWRS Advanced II&C pathway, Human Factors experts at Idaho National Laboratory (INL) have been conducting R&D in support of NPP main control room (MCR) modernization activities. Work in prior years has focused on migrating analog I&C systems to new digital I&C systems (). In fiscal year 2016 (FY16), one new focus area for this research is migrating older digital I&C systems to new and advanced digital I&C systems. This report summarizes a plan for conducting a digital-to-digital migration of a legacy digital I&C system to a new digital I&C system in support of control room modernization activities.

  12. Main factors affecting the fixing work about nuclear engineering and its discussion

    International Nuclear Information System (INIS)

    Zhang Zhihua; Liu Yaoguan; Qian Dazhi; Liu Hangang; Xu Xianqi; Deng Yue

    2010-01-01

    Main factors to the impact of the fixing work about nuclear engineering such as project design, construction, plan program, document, preparation, order, locale management, surveillance, quality assurance system and so on were presented. These factors were analyzed and discussed in this paper. Some measures and suggestions were put forward to accelerate construction fixing plan and insure good quality. We wish provide some references and help for someone engaged with construction of nuclear engineering. (authors)

  13. Simulation and analysis of main steam control system based on heat transfer calculation

    Science.gov (United States)

    Huang, Zhenqun; Li, Ruyan; Feng, Zhongbao; Wang, Songhan; Li, Wenbo; Cheng, Jiwei; Jin, Yingai

    2018-05-01

    In this paper, after thermal power plant 300MW boiler was studied, mat lab was used to write calculation program about heat transfer process between the main steam and boiler flue gas and amount of water was calculated to ensure the main steam temperature keeping in target temperature. Then heat transfer calculation program was introduced into Simulink simulation platform based on control system multiple models switching and heat transfer calculation. The results show that multiple models switching control system based on heat transfer calculation not only overcome the large inertia of main stream temperature, a large hysteresis characteristic of main stream temperature, but also adapted to the boiler load changing.

  14. WORKPLACE MOTIVATION IN ROMANIA: WHAT ARE THE MAIN FACTORS AND THEIR CULTURAL BACKGROUND?

    OpenAIRE

    Lauren?iu HAUSER

    2014-01-01

    Workplace motivation strongly depends on local cultural values. But while there is a large number of studies that focus on the US-American and Western European background, the specifically Romanian factors still remain in the shadow. This text aims to explain the main factors that form the „typically Romanian” set of social employee needs and their origin.

  15. Further improvement of human-machine interface for ABWR main control room

    International Nuclear Information System (INIS)

    Makino, S.

    2001-01-01

    Tokyo Electric Power Company (TEPCO) has developed main control room panels based on progress in C and I technology. ABWR type main control room panels (ABWR MCR PNLs) are categorized as third generation type domestic BWR MCR, that is, they are were developed step by step based on operating experience with the first and the second generation BWR. ABWR type main control room panels were applied to Kashiwazaki-Kariwa Nuclear Power Station Units Number 6 and 7 (K-6/7) for the first time. K-6/7 are the first advanced BWR (ABWR), which started commercial operation in November 1996 and July 1997, respectively. The concept of ABWR MCR design was verified through wooden mock-up panels, start-up tests and commercial operation. Though the K-6/7 design has borne fruit, we are planning to refine and standardize the design based on the following concepts: to maintain the plant operation and monitoring style of ABWR MCR PNLs; to introduce brand-new HMI technology and devices; to incorporate operators' advice in the design. This paper outlines the features and improvements of the K6/7 MCR PNLs design. (author)

  16. Measuring Situation Awareness of Operating Team in Different Main Control Room Environments of Nuclear Power Plants

    Directory of Open Access Journals (Sweden)

    Seung Woo Lee

    2016-02-01

    Full Text Available Environments in nuclear power plants (NPPs are changing as the design of instrumentation and control systems for NPPs is rapidly moving toward fully digital instrumentation and control, and modern computer techniques are gradually introduced into main control rooms (MCRs. Within the context of these environmental changes, the level of performance of operators in a digital MCR is a major concern. Situation awareness (SA, which is used within human factors research to explain to what extent operators of safety-critical systems know what is transpiring in the system and the environment, is considered a prerequisite factor to guarantee the safe operation of NPPs. However, the safe operation of NPPs can be guaranteed through a team effort. In this regard, the operating team's SA in a conventional and digital MCR should be measured in order to assess whether the new design features implemented in a digital MCR affect this parameter. This paper explains the team SA measurement method used in this study and the results of applying this measurement method to operating teams in different MCR environments. The paper also discusses several empirical lessons learned from the results.

  17. A review of the main driving factors of forest fire ignition over Europe.

    Science.gov (United States)

    Ganteaume, Anne; Camia, Andrea; Jappiot, Marielle; San-Miguel-Ayanz, Jesus; Long-Fournel, Marlène; Lampin, Corinne

    2013-03-01

    Knowledge of the causes of forest fires, and of the main driving factors of ignition, is an indispensable step towards effective fire prevention policies. This study analyses the factors driving forest fire ignition in the Mediterranean region including the most common human and environmental factors used for modelling in the European context. Fire ignition factors are compared to spatial and temporal variations of fire occurrence in the region, then are compared to results obtained in other areas of the world, with a special focus on North America (US and Canada) where a significant number of studies has been carried out on this topic. The causes of forest fires are varied and their distribution differs among countries, but may also differ spatially and temporally within the same country. In Europe, and especially in the Mediterranean basin, fires are mostly human-caused mainly due arson. The distance to transport networks and the distance to urban or recreation areas are among the most frequently used human factors in modelling exercises and the Wildland-Urban Interface is increasingly taken into account in the modelling of fire occurrence. Depending on the socio-economic context of the region concerned, factors such as the unemployment rate or variables linked to agricultural activity can explain the ignition of intentional and unintentional fires. Regarding environmental factors, those related to weather, fuel and topography are the most significant drivers of ignition of forest fires, especially in Mediterranean-type regions. For both human and lightning-caused fires, there is a geographical gradient of fire ignition, mainly due to variations in climate and fuel composition but also to population density for instance. The timing of fires depends on their causes. In populated areas, the timing of human-caused fires is closely linked to human activities and peaks in the afternoon whereas, in remote areas, the timing of lightning-caused fires is more linked to

  18. Research on design method of main control room intake air radioactive monitoring

    International Nuclear Information System (INIS)

    Li Lei; Sun Yu; Wang Jiaoya; Liu Hongtao

    2014-01-01

    According to the design of the main control room intake gamma radiation dose rate monitoring channels in CPR1000 project and the study of relevant regulations and standards, a design method of main control room air inlet radioactive monitoring was presented. The measured object, equipment layout and chain operation were described. The threshold setting was explored using a calculation model established by MCNP software. The advantages, disadvantages and improvement ideas of this design were presented on the basis of calculation results. (authors)

  19. Human factors engineering applied to Control Centre Design of a research nuclear reactor

    Energy Technology Data Exchange (ETDEWEB)

    Farias, Larissa P. de; Santos, Isaac J.A. Luquetti dos; Carvalho, Paulo V.R., E-mail: larissapfarias@ymail.com [Instituto de Engenharia Nuclear (DENN/SEESC/IEN/CNEN-RJ), Rio de Janeiro, RJ (Brazil). Lab, de Usabilidade e Confiabilidade Humana; Monteiro, Beany G. [Universidade Federal do Rio Janeiro (UFRJ), Rio Janeiro, RJ (Brazil). Departamento de Desenho Industrial

    2017-07-01

    The Human Factors Engineering (HFE) program is an essential aspect for the design of nuclear installations. The overall aim of the HFE program is the improvement of the operational reliability and safety of plant operation. The HFE program main purpose is to ensure that human factor practices are incorporated into the plant design, emphasizing man-machine interface issues and design improvement of the nuclear reactor Control Centre. The Control Centre of nuclear reactor is a combination of control rooms, control suites and local control stations, which are functionally connected and located on the reactor site. The objective of this paper is to present a design approach for the Control Centre of a nuclear reactor used to produce radioisotopes and for nuclear research, including human factor issues. The design approach is based on participatory design principles, using human factor standards, ergonomic guidelines, and the participation of a multidisciplinary team during all design phases. Using the information gathered, an initial sketch 3D of the Control Centre was developed. (author)

  20. Human factors engineering applied to Control Centre Design of a research nuclear reactor

    International Nuclear Information System (INIS)

    Farias, Larissa P. de; Santos, Isaac J.A. Luquetti dos; Carvalho, Paulo V.R.; Monteiro, Beany G.

    2017-01-01

    The Human Factors Engineering (HFE) program is an essential aspect for the design of nuclear installations. The overall aim of the HFE program is the improvement of the operational reliability and safety of plant operation. The HFE program main purpose is to ensure that human factor practices are incorporated into the plant design, emphasizing man-machine interface issues and design improvement of the nuclear reactor Control Centre. The Control Centre of nuclear reactor is a combination of control rooms, control suites and local control stations, which are functionally connected and located on the reactor site. The objective of this paper is to present a design approach for the Control Centre of a nuclear reactor used to produce radioisotopes and for nuclear research, including human factor issues. The design approach is based on participatory design principles, using human factor standards, ergonomic guidelines, and the participation of a multidisciplinary team during all design phases. Using the information gathered, an initial sketch 3D of the Control Centre was developed. (author)

  1. Imitative modeling automatic system Control of steam pressure in the main steam collector with the influence on the main Servomotor steam turbine

    Science.gov (United States)

    Andriushin, A. V.; Zverkov, V. P.; Kuzishchin, V. F.; Ryzhkov, O. S.; Sabanin, V. R.

    2017-11-01

    The research and setting results of steam pressure in the main steam collector “Do itself” automatic control system (ACS) with high-speed feedback on steam pressure in the turbine regulating stage are presented. The ACS setup is performed on the simulation model of the controlled object developed for this purpose with load-dependent static and dynamic characteristics and a non-linear control algorithm with pulse control of the turbine main servomotor. A method for tuning nonlinear ACS with a numerical algorithm for multiparametric optimization and a procedure for separate dynamic adjustment of control devices in a two-loop ACS are proposed and implemented. It is shown that the nonlinear ACS adjusted with the proposed method with the regulators constant parameters ensures reliable and high-quality operation without the occurrence of oscillations in the transient processes the operating range of the turbine loads.

  2. Quality control of three main materials for civil construction of nuclear power plant

    International Nuclear Information System (INIS)

    Wang Feng

    2011-01-01

    The construction and operation of nuclear power plant is a systematic engineering. To ensure quality and safety of nuclear power plants, each work from design to operation can have certain impact on the quality and safety of the project. The quality of each related work shall be controlled. Starting from the quality control over raw materials for the civil construction of nuclear power plant, this article mainly analyzes how to control the quality and manage the three main materials of steel, concrete and modular parts in the civil construction. (author)

  3. Factors controlling upper tropospheric relative humidity

    Directory of Open Access Journals (Sweden)

    B. Kärcher

    2004-03-01

    Full Text Available Factors controlling the distribution of relative humidity in the absence of clouds are examined, with special emphasis on relative humidity over ice (RHI under upper tropospheric and lower stratospheric conditions. Variations of temperature are the key determinant for the distribution of RHI, followed by variations of the water vapor mixing ratio. Multiple humidity modes, generated by mixing of different air masses, may contribute to the overall distribution of RHI, in particular below ice saturation. The fraction of air that is supersaturated with respect to ice is mainly determined by the distribution of temperature. The nucleation of ice in cirrus clouds determines the highest relative humdity that can be measured outside of cirrus clouds. While vertical air motion and ice microphysics determine the slope of the distributions of RHI, as shown in a separate study companion (Haag et al., 2003, clouds are not required to explain the main features of the distributions of RHI below the ice nucleation threshold. Key words. Atmospheric composition and structure (pressure, density and temperature; troposphere – composition and chemistry; general or miscellaneous

  4. Factors controlling upper tropospheric relative humidity

    Directory of Open Access Journals (Sweden)

    B. Kärcher

    2004-03-01

    Full Text Available Factors controlling the distribution of relative humidity in the absence of clouds are examined, with special emphasis on relative humidity over ice (RHI under upper tropospheric and lower stratospheric conditions. Variations of temperature are the key determinant for the distribution of RHI, followed by variations of the water vapor mixing ratio. Multiple humidity modes, generated by mixing of different air masses, may contribute to the overall distribution of RHI, in particular below ice saturation. The fraction of air that is supersaturated with respect to ice is mainly determined by the distribution of temperature. The nucleation of ice in cirrus clouds determines the highest relative humdity that can be measured outside of cirrus clouds. While vertical air motion and ice microphysics determine the slope of the distributions of RHI, as shown in a separate study companion (Haag et al., 2003, clouds are not required to explain the main features of the distributions of RHI below the ice nucleation threshold.

    Key words. Atmospheric composition and structure (pressure, density and temperature; troposphere – composition and chemistry; general or miscellaneous

  5. Improvement on Main/backup Controller Switching Device of the Nozzle Throat Area Control System for a Turbofan Aero Engine

    Science.gov (United States)

    Li, Jie; Duan, Minghu; Yan, Maode; Li, Gang; Li, Xiaohui

    2014-06-01

    A full authority digital electronic controller (FADEC) equipped with a full authority hydro-mechanical backup controller (FAHMBC) is adopted as the nozzle throat area control system (NTACS) of a turbofan aero engine. In order to ensure the switching reliability of the main/backup controller, the nozzle throat area control switching valve was improved from three-way convex desktop slide valve to six-way convex desktop slide valve. Simulation results show that, if malfunctions of FAEDC occur and abnormal signals are outputted from FADEC, NTACS will be seriously influenced by the main/backup controller switching in several working states, while NTACS will not be influenced by using the improved nozzle throat area control switching valve, thus the controller switching process will become safer and smoother and the working reliability of this turbofan aero engine is improved by the controller switching device improvement.

  6. Trigger factors mainly from the environmental type are reported by adolescents with migraine

    Directory of Open Access Journals (Sweden)

    Marcela Dalla Bernardina Fraga

    2013-05-01

    Full Text Available Migraine can be triggered by many factors such as stress, sleep, fasting and environmental causes. There are few studies that evaluated migraine trigger factors in the adolescent population. Methods: A total of 100 participants from 10 to 19 years were subjected to a detailed headache questionnaire, with demographic and clinical data, and a headache diary including trigger factors during a two-month period was asked. Results: Fifty of the participants exhibited chronic migraine and the other 50 participants demonstrated episodic migraine. The most common group of trigger factors reported was the environmental one, mainly sun/clarity, followed by hot weather and the smell of perfume. Conclusions: Ninety-one percent of children and adolescents with migraine reported a trigger factor precipitating the migraine attack.

  7. Risk Factors for Anemia in Pregnancy: A Case Control Study

    Directory of Open Access Journals (Sweden)

    Rutuja Pundkar

    2017-12-01

    Full Text Available Background: Aim of the study was to find the risk factors leading to Anemia in pregnancy. The main objective was to study the various sociodemographic factors leading to anemia. And to assess the knowledge about anemia among study participants. Material and methods: The present Case control study was carried out at Primary Health Centre, to determine the risk factors leading to anemia in pregnancy. A total of 308 pregnant females were registered. Among them two groups were made, group I cases and group II controls. Each group had 50 cases each. Laboratory test were done and females having hemoglobin less than 11mg/dl were considered anemic. Anemic females were considered cases and females having Hb >11mg/dl were considered controls. Data analysis was done using SPSS software. Results: The overall mean haemoglobin (Hb was 11.55g/dL in controls, whereas it was seen that among the cases it was 9.58g/dL.It would seem that diet, family size, education, social class, gravida and parity are associated with anemia in pregnancy. Conclusion: After adjusting for all the possible covariates there seems to be significant association between Hb levels and age group, education level, family size, diet, gravida and parity.

  8. The New Control and Interlock System for the SPS Main Power Converters

    CERN Document Server

    Denis, B; Mugnier, C; Varas, J

    1999-01-01

    The Control and Interlock System (CIS) of the SPS main power converters was designed in the mid-70s and became increasingly difficult to maintain. A new system based on Programmable Logic Controllers has been developed by an external contractor in close collaboration with CERN. The system is now operational and fully integrated in the SPS/LEP control infrastructure. The CIS is the first major contracted industrial solution used to control accelerator equipment directly involved in the production of particle beams at CERN. This paper gives an overview of the SPS main power converter installation and describes both the contractual and technical solution adopted for the CIS. It first explains how the system was specified and how the contractual relationship was defined to respect CERN’s purchasing rules and the operational requirements of the SPS accelerator. The architectural design of the new system is presented with special emphasis on how the conflict between safety and availability has been addressed.

  9. Analysis on nuclear power plant control room system design and improvement based on human factor engineering

    International Nuclear Information System (INIS)

    Gao Feng; Liu Yanzi; Sun Yongbin

    2014-01-01

    The design of nuclear power plant control room system is a process of improvement with the implementation of human factor engineering theory and guidance. The method of implementation human factor engineering principles into the nuclear power plant control room system design and improvement was discussed in this paper. It is recommended that comprehensive address should be done from control room system function, human machine interface, digital procedure, control room layout and environment design based on the human factor engineering theory and experience. The main issues which should be paid more attention during the control room system design and improvement also were addressed in this paper, and then advices and notices for the design and improvement of the nuclear power plant control room system were afforded. (authors)

  10. Main control computer security model of closed network systems protection against cyber attacks

    Science.gov (United States)

    Seymen, Bilal

    2014-06-01

    The model that brings the data input/output under control in closed network systems, that maintains the system securely, and that controls the flow of information through the Main Control Computer which also brings the network traffic under control against cyber-attacks. The network, which can be controlled single-handedly thanks to the system designed to enable the network users to make data entry into the system or to extract data from the system securely, intends to minimize the security gaps. Moreover, data input/output record can be kept by means of the user account assigned for each user, and it is also possible to carry out retroactive tracking, if requested. Because the measures that need to be taken for each computer on the network regarding cyber security, do require high cost; it has been intended to provide a cost-effective working environment with this model, only if the Main Control Computer has the updated hardware.

  11. A 3-Year Workplace-Based Intervention Program to Control Noncommunicable Disease Risk Factors in Sousse, Tunisia.

    Science.gov (United States)

    Bhiri, Sana; Maatoug, Jihene; Zammit, Nawel; Msakni, Zineb; Harrabi, Imed; Amimi, Souad; Mrizek, Nejib; Ghannem, Hassen

    2015-07-01

    To assess the effectiveness of a 3-year workplace-based intervention program on the control of the main noncommunicable disease risk factors (poor nutrition, physical inactivity, and tobacco use) among the employees of Sousse, Tunisia. We conducted a quasi-experimental study (pre- and postassessments with intervention and control groups) in six companies of the governorate of Sousse in Tunisia.The intervention program consisted of health education programs (eg, workshops, films and open sensitization days). We also scheduled free physical activity sessions and free smoking cessation consultations. Our intervention program showed meaningful improvement among the employees toward dietary and physical activity behaviors but not for tobacco use. Workplace is a crucial setting for health promotion, and future programs should consider a multisectoral approach to control the main noncommunicable disease risk factors.

  12. Improvement on main control room for Japanese PWR plants

    International Nuclear Information System (INIS)

    Matsumiya, Masayuki

    1996-01-01

    The main control room which is the information center of nuclear power plant has been continuously improved utilizing the state of the art ergonomics, a high performance computer, computer graphic technologies, etc. For the latest Japanese Pressurized Water Reactor (PWR) plant, the CRT monitoring system is applied as the major information source for facilitating operators' plant monitoring tasks. For an operating plant, enhancement of monitoring and logging functions has been made adopting a high performance computer

  13. The role of hormones and growth factors in the cellular proliferation control in mammals

    International Nuclear Information System (INIS)

    Armelin, H.A.

    1978-01-01

    A review is done about fibroblast proliferation, its control by classic hormones and hormonal growth factors, showing their main implications and the stage of this research at present. The control exerted on fibronlast proliferation by hormonal growth factors and classic hormones is demonstrated. The existence of basic mechanisms valid for all types of cells is suggested. Experiences are carried out with the aim of finding growth mutants useful in the elucidation of the biochemical mechanisms involved in growth regulation. Radiactive precursors and autoradiographic techniques are used in the research. (M.A.) [pt

  14. Main cycle controls for the AGS Booster synchrotron

    International Nuclear Information System (INIS)

    Culwick, B.B.; Yen, S.

    1991-01-01

    The AGS Booster is a separated function synchrotron with the main excitation coils of the dipoles and quadrupoles connected electrically in series. This circuit is driven by a complex modular power supply with current and voltage reference functions to obtain the desired magnetic fields as a function of time. The dipole cycle is defined by algebraic functions specifying the desired field profile as a function of time. These functions are processed through successive phases to convert to the signals needed to provide the power supply with one current and six voltage references. The user interface and algorithms to derive the control variables are described. 4 refs., 3 figs

  15. The human factors specialist in nuclear control centre design

    International Nuclear Information System (INIS)

    Wilson, R.B.; Beattie, J.D.

    The main focus at Ontario Hydro for man-machine interface design is in the design of control centres. Because the control of a nuclear generating unit is highly centralized there is an increasing need for effective information display and control layout. Control panel design innovations such as the use of CRT displays and the extended use of computerized control in the Darlington station have made it possible for Ontario Hydro to continue to have one first operator for each generating unit. The human factors specialist involved in control panel design must deal with people who know much more about the specific systems being controlled, and must become a generalist in all these systems as well. Designers have to use conceptual techniques such as task analysis, systems design, panel mock-ups, anthropometric data, and personal judgement based on experience as they design panels. They must find a balance between becoming locked into existing technology and methods, slavishly following the latest technological trends, and forgetting that real people will be using what they design

  16. Service Quality: A Main Determinant Factor for Health Information System Success in Low-resource Settings.

    Science.gov (United States)

    Tilahun, Binyam; Fritz, Fleur

    2015-01-01

    With the increasing implementation of different health information systems in developing countries, there is a growing need to measure the main determinants of their success. The results of this evaluation study on the determinants of HIS success in five low resource setting hospitals show that service quality is the main determinant factor for information system success in those kind of settings.

  17. Development of a hardware-in- loop simulation platform for NPP main control systems

    Directory of Open Access Journals (Sweden)

    Liu Pengfei

    2017-01-01

    Full Text Available The simulation technology of the nuclear power plant are gradually applying to the nuclear power industry. However, most of the research on nuclear power plant simulation system only focus on pure computerized simulation at present, and it is difficult to fully display the characteristics of the simulating objects. In order to simulate the response characteristics of control system more really, a hardware-in-loop simulation platform of main control systems in the nuclear power plant has been developed in this paper. This simulation platform consists of thermal-hydraulic model, control and protection system model, physical DCS system and real-time interactive database. A physical industrial DCS system has been coupled to this platform to simulate the main control systems in the NPP, which makes the simulation result much closer to the actual control systems. The devoloped simulation platform has been validated by some steady and transient cases in this paper. This hardware-in-loop simulation platform can be used in the simulation and optimal design of NPP control systems. Furthermore, it can be used in the failure mode and effect analysis of the instrumentation and control systems in the nuclear power plant.

  18. Supplementary control points for reactor shutdown without access to the main control room (International Electrotechnical Commission Standard Publication 965:1989)

    International Nuclear Information System (INIS)

    Kubalek, J.; Hajek, B.

    1993-01-01

    This standard establishes the requirements for supplementary Control Points provided to enable the operating staff to shut down the reactor and maintain the plant in a safe shut-down condition when the main control room is no longer available. This standard covers the functional selection, design and organization of the man/machine interface. It also establishes requirements for procedures which systematically verify and validate the functional design of supplementary control points. The requirements reflect the application of human engineering principles as they apply to man/machine interface. This standard does not cover special emergency response centres (e.g. a Technical Support Centre). It also does not include the detailed equipment design. Unavailability of the main control room controls due to intentionally man-induced events is not considered

  19. Biological stability of drinking water: controlling factors, methods and challenges

    Directory of Open Access Journals (Sweden)

    Emmanuelle ePrest

    2016-02-01

    Full Text Available Biological stability of drinking water refers to the concept of providing consumers with drinking water of same microbial quality at the tap as produced at the water treatment facility. However, uncontrolled growth of bacteria can occur during distribution in water mains and premise plumbing, and can lead to hygienic (e.g. development of opportunistic pathogens, aesthetic (e.g. deterioration of taste, odour, colour or operational (e.g. fouling or biocorrosion of pipes problems. Drinking water contains diverse microorganisms competing for limited available nutrients for growth. Bacterial growth and interactions are regulated by factors such as (i type and concentration of available organic and inorganic nutrients, (ii type and concentration of residual disinfectant, (iii presence of predators such as protozoa and invertebrates, (iv environmental conditions such as water temperature, and (v spatial location of microorganisms (bulk water, sediment or biofilm. Water treatment and distribution conditions in water mains and premise plumbing affect each of these factors and shape bacterial community characteristics (abundance, composition, viability in distribution systems. Improved understanding of bacterial interactions in distribution systems and of environmental conditions impact is needed for better control of bacterial communities during drinking water production and distribution. This article reviews (i existing knowledge on biological stability controlling factors and (ii how these factors are affected by drinking water production and distribution conditions. In addition, (iii the concept of biological stability is discussed in light of experience with well-established and new analytical methods, enabling high throughput analysis and in-depth characterization of bacterial communities in drinking water. We discuss how knowledge gained from novel techniques will improve design and monitoring of water treatment and distribution systems in order to

  20. Biological Stability of Drinking Water: Controlling Factors, Methods, and Challenges

    Science.gov (United States)

    Prest, Emmanuelle I.; Hammes, Frederik; van Loosdrecht, Mark C. M.; Vrouwenvelder, Johannes S.

    2016-01-01

    Biological stability of drinking water refers to the concept of providing consumers with drinking water of same microbial quality at the tap as produced at the water treatment facility. However, uncontrolled growth of bacteria can occur during distribution in water mains and premise plumbing, and can lead to hygienic (e.g., development of opportunistic pathogens), aesthetic (e.g., deterioration of taste, odor, color) or operational (e.g., fouling or biocorrosion of pipes) problems. Drinking water contains diverse microorganisms competing for limited available nutrients for growth. Bacterial growth and interactions are regulated by factors, such as (i) type and concentration of available organic and inorganic nutrients, (ii) type and concentration of residual disinfectant, (iii) presence of predators, such as protozoa and invertebrates, (iv) environmental conditions, such as water temperature, and (v) spatial location of microorganisms (bulk water, sediment, or biofilm). Water treatment and distribution conditions in water mains and premise plumbing affect each of these factors and shape bacterial community characteristics (abundance, composition, viability) in distribution systems. Improved understanding of bacterial interactions in distribution systems and of environmental conditions impact is needed for better control of bacterial communities during drinking water production and distribution. This article reviews (i) existing knowledge on biological stability controlling factors and (ii) how these factors are affected by drinking water production and distribution conditions. In addition, (iii) the concept of biological stability is discussed in light of experience with well-established and new analytical methods, enabling high throughput analysis and in-depth characterization of bacterial communities in drinking water. We discussed, how knowledge gained from novel techniques will improve design and monitoring of water treatment and distribution systems in order

  1. Biological Stability of Drinking Water: Controlling Factors, Methods, and Challenges

    KAUST Repository

    Prest, Emmanuelle I.

    2016-02-01

    Biological stability of drinking water refers to the concept of providing consumers with drinking water of same microbial quality at the tap as produced at the water treatment facility. However, uncontrolled growth of bacteria can occur during distribution in water mains and premise plumbing, and can lead to hygienic (e.g., development of opportunistic pathogens), aesthetic (e.g., deterioration of taste, odor, color) or operational (e.g., fouling or biocorrosion of pipes) problems. Drinking water contains diverse microorganisms competing for limited available nutrients for growth. Bacterial growth and interactions are regulated by factors, such as (i) type and concentration of available organic and inorganic nutrients, (ii) type and concentration of residual disinfectant, (iii) presence of predators, such as protozoa and invertebrates, (iv) environmental conditions, such as water temperature, and (v) spatial location of microorganisms (bulk water, sediment, or biofilm). Water treatment and distribution conditions in water mains and premise plumbing affect each of these factors and shape bacterial community characteristics (abundance, composition, viability) in distribution systems. Improved understanding of bacterial interactions in distribution systems and of environmental conditions impact is needed for better control of bacterial communities during drinking water production and distribution. This article reviews (i) existing knowledge on biological stability controlling factors and (ii) how these factors are affected by drinking water production and distribution conditions. In addition, (iii) the concept of biological stability is discussed in light of experience with well-established and new analytical methods, enabling high throughput analysis and in-depth characterization of bacterial communities in drinking water. We discussed, how knowledge gained from novel techniques will improve design and monitoring of water treatment and distribution systems in order

  2. Factors analysis of water hammer in FLOWMASTER for main feedwater systems of PWR nuclear power plants

    International Nuclear Information System (INIS)

    Wang Xin; Han Weishi

    2010-01-01

    The main feedwater system of a nuclear power plant (NPP) is an important part in ensuring the cooling of a steam generator. It is the main pipe section where water hammers frequently occur. Studying the regulator patterns of water hammers in the main feedwater systems is significant to the stable operation of the system. This article focuses on a parametric study to avoid the consequences of water hammer effect in PWR by employing a general purpose fluid dynamic simulation software-FLOWMASTER. Through FLOWMASTER's transient calculating functions, a mathematical model is established with boundary conditions such as feedwater pumps, control valves, etc., calculations of water hammer pressure when feedwater pumps and control valves shut down, and simulations during instantaneous changes in water hammer pressure. Combining a plethora of engineering practical examples, this research verified the viability of calculating water hammer pressure through FLOWMASTER's transient functions and we found out that, increasing the periods of closure of control valves and feedwater pumps control water hammers effectively. We also found out that changing the intervals of closing signals to feedwater pumps and control valves aid to relieve hydraulic impact. This could be a guideline for practical engineering design and system optimization. (author)

  3. Predictive factors for renal failure and a control and treatment algorithm

    Directory of Open Access Journals (Sweden)

    Denise de Paula Cerqueira

    2014-04-01

    Full Text Available OBJECTIVES: to evaluate the renal function of patients in an intensive care unit, to identify the predisposing factors for the development of renal failure, and to develop an algorithm to help in the control of the disease.METHOD: exploratory, descriptive, prospective study with a quantitative approach.RESULTS: a total of 30 patients (75.0% were diagnosed with kidney failure and the main factors associated with this disease were: advanced age, systemic arterial hypertension, diabetes mellitus, lung diseases, and antibiotic use. Of these, 23 patients (76.6% showed a reduction in creatinine clearance in the first 24 hours of hospitalization.CONCLUSION: a decline in renal function was observed in a significant number of subjects, therefore, an algorithm was developed with the aim of helping in the control of renal failure in a practical and functional way.

  4. MAIN FACTORS DRIVING SOCIAL PUBLIC SERVICES IN INTERNATIONAL CONTEXT

    Directory of Open Access Journals (Sweden)

    Mihaela, GHENTA

    2014-03-01

    Full Text Available Literature and the latest reports point out that not only in Europe, but all over the world there is a growing demand for social services. As social needs have diversified, the number of potential users of social services has increased and this has generated increased complexity of social services. This paper highlights some of the results of a study conducted by the author in the doctoral studies program. One of the aims of this study was to identify the main factors that cause the current configuration of social services at global level. The research analysed the demographic changes and the impact of the crisis in social services for Europe, the United States of America (USA and Japan based on statistical data provided by the national statistics institutes for the regions considered. The results highlight the necessity of continuous development and reconfiguration of social services in order to meet the social and economic demands and to ensure a better organisation of these type of services.

  5. Application of the reliability theory on the analysis of the effects of sbwr' main control console maintenance

    International Nuclear Information System (INIS)

    Widagdo, S.

    1997-01-01

    Maintenance activities on the main control console, which is a primary element of the man-machine interface system, are a source of concern. this concern has been arisen since the main control function is the central part to observe and control the reactor operation. the paper will discuss a study of the effects of main control console maintenance activity upon the operability of SBWR. the first step is learning the SBWR main control room design in order to know its monitoring and controlling capability and then makes an assumption of maintenance requirement followed by an evaluation of the effects of the maintenance activity. it is assumed that 2 years or equivalent to 17.520 hours are the reference time for one cycle operation of SBWR. the aim is to identify any adverse effects and eliminate or minimize them through design improvements. the evaluation method used here is the reability theory R(t) = e sup-λt. Based on the result of the evaluation can be concluded that there are no negative effects of maintenance activity upon the operability of the SBWR

  6. A HUMAN FACTORS META MODEL FOR U.S. NUCLEAR POWER PLANT CONTROL ROOM MODERNIZATION

    Energy Technology Data Exchange (ETDEWEB)

    Joe, Jeffrey C.

    2017-03-01

    Over the last several years, the United States (U.S.) Department of Energy (DOE) has sponsored human factors research and development (R&D) and human factors engineering (HFE) activities through its Light Water Reactor Sustainability (LWRS) program to modernize the main control rooms (MCR) of commercial nuclear power plants (NPP). Idaho National Laboratory (INL), in partnership with numerous commercial nuclear utilities, has conducted some of this R&D to enable the life extension of NPPs (i.e., provide the technical basis for the long-term reliability, productivity, safety, and security of U.S. NPPs). From these activities performed to date, a human factors meta model for U.S. NPP control room modernization can now be formulated. This paper discusses this emergent HFE meta model for NPP control room modernization, with the goal of providing an integrated high level roadmap and guidance on how to perform human factors R&D and HFE for those in the U.S. nuclear industry that are engaging in the process of upgrading their MCRs.

  7. Performance of Anidolic Daylighting Systems in tropical climates - Parametric studies for identification of main influencing factors

    Energy Technology Data Exchange (ETDEWEB)

    Linhart, Friedrich; Scartezzini, Jean-Louis [Solar Energy and Building Physics Laboratory (LESO-PB), Swiss Federal Institute of Technology in Lausanne (EPFL), 1015 Lausanne (Switzerland); Wittkopf, Stephen K. [School of Design and Environment, Department of Architecture, National University of Singapore, 4 Architecture Drive, Singapore 117566 (Singapore)

    2010-07-15

    Making daylight more available in buildings is highly desirable, not only for reasons of energy-efficiency, but also for improvement of occupants' health and well-being. Core-daylighting, that is daylight provision in areas situated at considerable distances from facades and windows, is currently one of the main challenges in sustainable building design. Anidolic Daylighting Systems (ADSs) are one very promising technology in the field of core-daylighting, but commercial solutions that are not only well-performing but also financially competitive are not yet widely available. This article presents results of parametric studies on Anidolic Integrated Ceilings (AICs), a special type of ADS, for identification of main influencing factors. The article describes a reliable method for simulating ADS and AIC performance under given sky conditions. Various simulation results for the example location Singapore are discussed in detail, it is concluded that the main influencing factors are coating material, system dimensions and external obstruction, and those influencing factors' potential impacts are quantified. It is shown that AIC overall efficiencies can reach up to almost 50% in Singapore. The essentially new results presented in this article can be of great help to architects, engineers and scientists in the future, when it comes to precisely dimensioning ADS for various buildings and daylight conditions. (author)

  8. Differential accumulation and distribution of natural gas and its main controlling factors in the Sinian Dengying Fm, Sichuan Basin

    Directory of Open Access Journals (Sweden)

    Shugen Liu

    2015-01-01

    Full Text Available In order to disclose the genetic relationship between the hydrocarbon reservoirs and the transformation mechanism between ancient and modern gas reservoirs in the Sinian Dengying Fm in the Sichuan Basin, by using the drilling data, and geologic, geophysical and geochemical methods together, the differential accumulation and distribution of natural gas and its main controlling factors in this study area were identified following the idea of corroborating macroscopic, mesoscopic and microscopic results each other. The results demonstrate as follows. (1 The crude oil in the paleo-oil reservoirs of the Dengying Fm cracked into gas to form the early overpressure paleo-gas reservoirs 100 Ma. From 100 Ma to 20 Ma, the constant uplifting of the Sichuan Basin coupled with the shift of structural highs and the initial occurrence of Weiyuan anticline caused the adjustment of the early overpressure paleo-gas reservoirs into the late overpressure paleo-gas reservoirs. (2 With the increase of uplifting magnitude since 20 Ma, the formations overlying the Dengying Fm in Weiyuan structure experienced rapid erosion, resulting in decline of the caprock sealing ability and damage to the preservation conditions. Therefore, the natural gas in the Dengying Fm started to leak and dissipate from the eroded window of the Lower Triassic Jialingjiang Fm located on the top of the Weiyuan anticline, which is the beginning of the differential accumulation and dissipation of the natural gas in the Dengying Fm across the Sichuan Basin. During the process of the differential accumulation and dissipation, the gas below the spill point of the structural gas traps in Ziyang, Jinshi and Longnüsi–Moxi–Anpingdian–Gaoshiti areas migrated to the Weiyuan anticline along the unconformity of the Dengying Fm, and dissipated through the eroded window of the Jialingjiang Fm on the top of the Weiyuan anticline, resulting in a transformation of abnormal high pressure of gas reservoir

  9. Digitized operator evaluation system for main control room of nuclear power plant

    International Nuclear Information System (INIS)

    Chen Yu; Yan Shengyuan; Chen Wenlong

    2014-01-01

    In order to evaluate the human-machine system matching relation of main control room in nuclear power plant accurately and efficiently, the expression and parameters of operator human body model were analyzed, and the evaluation required function of digital operator was determined. Based on the secondary development technology, the digital operator evaluation body model was developed. It could choose generation, gender, operation posture, single/eyes horizon, and left/right hand up to the domain according to the needs of specific evaluation, it was used to evaluate whether display information can be visible and equipment can be touch, and it also has key evaluation functions such as workspace and character visibility at the same time. The examples show that this method can complete the evaluation work of human-machine matching relation for main control room of nuclear power plant accurately, efficiently and quickly, and achieve the most optimal human-machine coordination relationship. (authors)

  10. The main features of control and operation of steam turbines at nuclear power plants

    International Nuclear Information System (INIS)

    Czinkoczky, B.

    1981-01-01

    The output and speed control of steam turbines at nuclear power plants as well as the combination of both controls are reviewed and evaluated. At the same time the tasks of unit control at nuclear power plants, the control of steady main steam pressure and medium pressure of primary circuit, further the connection of reactor and turbine controls and the self-controlling properties of pressurized water reactor are dealt with. Hydraulic and electro-hydraulic speed control, the connection of cach-up dampers and speed control and the application of electro-hydraulic signal converters are discussed. The accomplishment of protection is also described. (author)

  11. Human factors methods for nuclear control room design. Volume I. Human factors enhancement of existing nuclear control rooms. Final report

    International Nuclear Information System (INIS)

    Seminara, J.L.; Seidenstein, S.; Eckert, S.K.; Smith, D.L.

    1979-11-01

    Human factors engineering is an interdisciplinary specialty concerned with influencing the design of equipment systems, facilities, and operational environments to promote safe, efficient, and reliable operator performance. Human factors approaches were applied in the design of representative nuclear power plant control panels. First, methods for upgrading existing operational control panels were examined. Then, based on detailed human factors analyses of operator information and control requirements, designs of reactor, feedwater, and turbine-generator control panels were developed to improve the operator-control board interface, thereby reducing the potential for operator errors. In addition to examining present-generation concepts, human factors aspects of advanced systems and of hybrid combinations of advanced and conventional designs were investigated. Special attention was given to warning system designs. Also, a survey was conducted among control board designers to (1) develop an overview of design practices in the industry, and (2) establish appropriate measures leading to a more systematic concern for human factors in control board design

  12. AUTOMATIC CONTROL SYSTEM FOR REGULATED HIGH TEMPERATURE MAIN COMBUSTION CHAMBER OF MANEUVERABLE AIRCRAFT MULTIMODE GAS TURBINE ENGINE

    Directory of Open Access Journals (Sweden)

    T. V. Gras’Ko

    2014-01-01

    Full Text Available The paper describes choosing and substantiating the control laws, forming the appearance the automatic control system for regulated high temperature main combustion chamber of maneuverable aircraft multimode gas turbine engine aimed at sustainable and effective functioning of main combustion chamber within a broad operation range.

  13. Factors influencing organic-horizon carbon pools in mixed-species stands of central Maine, USA

    Science.gov (United States)

    Joshua J. Puhlick; Shawn Fraver; Ivan J. Fernandez; Aaron R. Weiskittel; Laura S. Kenefic; Randy Kolka; Marie-Cecile Gruselle

    2016-01-01

    The overall goal of this study was to evaluate the correlation of multiple abiotic and biotic factors with organic-horizon (O-horizon) carbon (C) content on the Penobscot Experimental Forest in central Maine, USA. O-horizon samples were collected and their associated depths were recorded from stands managed with a range of silvicultural and harvesting treatments (i.e...

  14. The simulation of control system for the KEK main ring power supply, 1

    International Nuclear Information System (INIS)

    Sato, Hikaru; Shintomi, Takakazu; Kubo, Tadashi; Masuda, Masayoshi; Nakano, Michio.

    1975-09-01

    The simulation of control system for the KEK main ring power supply is performed. The inductance of the magnet is assumed to be linear against to the current. The results of the simulations are described. (auth.)

  15. Design and su pply of main control rooms for nuclear progra mme in China Tecnatom has played a significant

    International Nuclear Information System (INIS)

    Rejas, L.; Martinez, V.

    2016-01-01

    Tecnatom has played a significant role in the challenging energy development programme in China, which expects to increase the production of nuclear energy in 150 GWe in 2030. Tecnatom scope of work consisted of the design and supply of 10 main control rooms for Fuqing 1-4, Fangjiashan 1-2, Hainan 1-2 and Yangjiang 5-6 nuclear power plants. These projects have reinforced Tecnatom capabilities on human factors engineering, operation environments design, equipment qualification, fabrication, testing and installation among others, in an international and complex environment, with very tight schedules, achieving very successful results. (Author)

  16. Design and su pply of main control rooms for nuclear progra mme in China Tecnatom has played a significant

    Energy Technology Data Exchange (ETDEWEB)

    Rejas, L.; Martinez, V.

    2016-07-01

    Tecnatom has played a significant role in the challenging energy development programme in China, which expects to increase the production of nuclear energy in 150 GWe in 2030. Tecnatom scope of work consisted of the design and supply of 10 main control rooms for Fuqing 1-4, Fangjiashan 1-2, Hainan 1-2 and Yangjiang 5-6 nuclear power plants. These projects have reinforced Tecnatom capabilities on human factors engineering, operation environments design, equipment qualification, fabrication, testing and installation among others, in an international and complex environment, with very tight schedules, achieving very successful results. (Author)

  17. Risk Assessment of the Main Control Room Fire Using Fire Simulations

    International Nuclear Information System (INIS)

    Kang, Dae Il; Kim, Kilyoo; Jang, Seung Cheol

    2013-01-01

    KAERI is performing a fire PSA for a reference plant, Ulchin Unit 3, as part of developing the Korean site risk profile (KSRP). Fire simulations of the MCR fire were conducted using the CFAST (Consolidated Fire Growth and Smoke Transport) model and FDS (fire dynamic simulator) to improve the uncertainty in the MCR fire risk analysis. Using the fire simulation results, the MCR abandonment risk was evaluated. Level 1 PSA (probabilistic safety assessment) results of Ulchin Unit 3 using the EPRI PRA (probabilistic risk assessment) implementation guide showed that the MCR (main control room) fire was the main contributor to the core damage frequency. Recently, U. S. NRC and EPRI developed NUREG/CR-6850 to provide state-of-the-art methods, tools, and data for the conduct of a fire PSA for a commercial NPP

  18. RESEARCH OF THE HIGH HARMONICS INDIVIDUAL BLADE CONTROL EFFECT ON VIBRATIONS CAUSED BY THE HELICOPTER MAIN ROTOR THRUST

    OpenAIRE

    2016-01-01

    The paper presents numerical results analysis of main rotor vibration due to helicopter main rotor thrust pulsation.The calculation method, the object of research and numerical research results with the aim to reduce the amplitude of the vibrations transmitted to the hub from the helicopters main rotor by the individual blade control in azimuth by the installation angle of blades cyclic changes are set out in the article. The individual blades control law for a five-blade main rotor based on ...

  19. Factors influencing the profitability of optimizing control systems

    International Nuclear Information System (INIS)

    Broussaud, A.; Guyot, O.

    1999-01-01

    Optimizing control systems supplement conventional Distributed Control Systems and Programmable Logic Controllers. They continuously implement set points, which aim at maximizing the profitability of plant operation. They are becoming an integral part of modern mineral processing plants. This trend is justified by economic considerations, optimizing control being among the most cost-effective methods of improving metallurgical plant performance. The paper successively analyzes three sets of factors, which influence the profitability of optimizing control systems, and provides guidelines for analyzing the potential value of an optimizing control system at a given operation: external factors, such as economic factors and factors related to plant feed; features of the optimizing control system; and subsequent maintenance of the optimizing control system. It is shown that pay back times for optimization control projects are typically measured in days. The OCS software used by the authors for their applications is described briefly. (author)

  20. Human factors methods for nuclear control room design. Volume 2. Human factors survey of control room design practices

    International Nuclear Information System (INIS)

    Seminara, J.L.; Parsons, S.O.

    1979-11-01

    An earlier review of the control rooms of operating nuclear power plants identified many design problems having potential for degrading operator performance. As a result, the formal application of human factors principles was found to be needed. This report demonstrates the use of human factors in the design of power plant control rooms. The approaches shown in the report can be applied to operating power plants, as well as to those in the design stage. This study documents human factors techniques required to provide a sustained concern for the man-machine interface from control room concept definition to system implementation

  1. Operational Strategy of CBPs for load balancing of Operators in Advanced Main Control Room

    International Nuclear Information System (INIS)

    Kim, Seunghwan; Kim, Yochan; Jung, Wondea

    2014-01-01

    With the using of a computer-based control room in an APR1400 (Advanced Pressurized Reactor-1400), the operators' behaviors in the main control room had changed. However, though the working environment of operators has been changed a great deal, digitalized interfaces can also change the cognitive tasks or activities of operators. First, a shift supervisor (SS) can confirm/check the conduction of the procedures and the execution of actions of board operators (BOs) while confirming directly the operation variables without relying on the BOs. Second, all operators added to their work the use of a new CBP and Soft Controls, increasing their procedural workload. New operational control strategies of CBPs are necessary for load balancing of operator's task load in APR1400. In this paper, we compared the workloads of operators in an APR1400 who work with two different usages of the CBP. They are SS oriented usage and SS-BO collaborative usage. In this research, we evaluated the workloads of operators in an advanced main control room by the COCOA method. Two types of CBP usages were defined and the effects of these usages on the workloads were investigated. The obtained results showed that the workloads between operators in a control room can be balanced according to the CBP usages by assigning control authority to the operators

  2. Operational Strategy of CBPs for load balancing of Operators in Advanced Main Control Room

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Seunghwan; Kim, Yochan; Jung, Wondea [Korea Atomic Energy Research Institute, Daejeon (Korea, Republic of)

    2014-05-15

    With the using of a computer-based control room in an APR1400 (Advanced Pressurized Reactor-1400), the operators' behaviors in the main control room had changed. However, though the working environment of operators has been changed a great deal, digitalized interfaces can also change the cognitive tasks or activities of operators. First, a shift supervisor (SS) can confirm/check the conduction of the procedures and the execution of actions of board operators (BOs) while confirming directly the operation variables without relying on the BOs. Second, all operators added to their work the use of a new CBP and Soft Controls, increasing their procedural workload. New operational control strategies of CBPs are necessary for load balancing of operator's task load in APR1400. In this paper, we compared the workloads of operators in an APR1400 who work with two different usages of the CBP. They are SS oriented usage and SS-BO collaborative usage. In this research, we evaluated the workloads of operators in an advanced main control room by the COCOA method. Two types of CBP usages were defined and the effects of these usages on the workloads were investigated. The obtained results showed that the workloads between operators in a control room can be balanced according to the CBP usages by assigning control authority to the operators.

  3. Multi-microprocessor control of the main ring magnet power supply of the 12 GeV KEK proton synchrotron

    International Nuclear Information System (INIS)

    Sueno, T.; Mikawa, K.; Toda, M.; Toyama, T.; Sato, H.; Matsumoto, S.

    1992-01-01

    A general description of the computer control system of the KEK 12 GeV PS main ring magnet power supply is given, including its peripheral devices. The system consists of the main HIDIC-V90/25 CPU and of the input and output controllers HISEC-04M. The main CPU, supervised by UNIX, provides the man-machine interfacing and implements the repetitive control algorithm to correct for any magnet current deviation from reference. Two sub-CPU's are linked by a LAN and supported by a real time multi-task monitor. The output process controller distributes the control patterns to 16-bit DAC's, at 1.67 ms clock period in synchronism with the 3-phase ac line systems. The input controller logs the magnet current and voltage, via 16-bit ADC's at the same clock rate. (author)

  4. Erectile Dysfunction Among HIV Patients Undergoing Highly Active Antiretroviral Therapy: Dyslipidemia as a Main Risk Factor

    Directory of Open Access Journals (Sweden)

    Gustavo Romero‐Velez, MD

    2014-04-01

    Conclusions: ED is highly prevalent in HIV patients. Dyslipidemia should be considered as a risk factor for ED in HIV patients. Romero‐Velez G, Lisker‐Cervantes A, Villeda‐Sandoval CI, Sotomayor de Zavaleta M, Olvera‐Posada D, Sierra‐Madero JG, Arreguin‐Camacho LO, and Castillejos‐Molina RA. Erectile dysfunction among HIV patients undergoing highly active antiretroviral therapy: Dyslipidemia as a main risk factor. Sex Med 2014;2:24–30.

  5. Characterizing Observed Limit Cycles in the Cassini Main Engine Guidance Control System

    Science.gov (United States)

    Rizvi, Farheen; Weitl, Raquel M.

    2011-01-01

    The Cassini spacecraft dynamics-related telemetry during long Main Engine (ME) burns has indicated the presence of stable limit cycles between 0.03-0.04 Hz frequencies. These stable limit cycles cause the spacecraft to possess non-zero oscillating rates for extended periods of time. This indicates that the linear ME guidance control system does not model the complete dynamics of the spacecraft. In this study, we propose that the observed limit cycles in the spacecraft dynamics telemetry appear from a stable interaction between the unmodeled nonlinear elements in the ME guidance control system. Many nonlinearities in the control system emerge from translating the linear engine gimbal actuator (EGA) motion into a spacecraft rotation. One such nonlinearity comes from the gear backlash in the EGA system, which is the focus of this paper. The limit cycle characteristics and behavior can be predicted by modeling this gear backlash nonlinear element via a describing function and studying the interaction of this describing function with the overall dynamics of the spacecraft. The linear ME guidance controller and gear backlash nonlinearity are modeled analytically. The frequency, magnitude, and nature of the limit cycle are obtained from the frequency response of the ME guidance controller and nonlinear element. In addition, the ME guidance controller along with the nonlinearity is simulated. The simulation response contains a limit cycle with similar characterstics as predicted analytically: 0.03-0.04 Hz frequency and stable, sustained oscillations. The analytical and simulated limit cycle responses are compared to the flight telemetry for long burns such as the Saturn Orbit Insertion and Main Engine Orbit Trim Maneuvers. The analytical and simulated limit cycle characteristics compare well with the actual observed limit cycles in the flight telemetry. Both have frequencies between 0.03-0.04 Hz and stable oscillations. This work shows that the stable limit cycles occur

  6. Applications of human factors engineering in the digital HMI

    International Nuclear Information System (INIS)

    Zhou Bingjian

    2014-01-01

    In order to prevent and minimize human errors in the digital main control room, the principles of human factors engineering must be complied strictly in the design process of digital human-machine interface. This paper briefly describes the basic human factors engineering principles of designing main control room, introduces the main steps to implement the human factors engineering verification and validation of main control room, including HSI task support verification, human factors engineering design verification and integrated system validation. Meanwhile, according to the new digital human-machine interface characteristics, the development models of human error are analyzed. (author)

  7. Continuous Trailing-Edge Flaps for Primary Flight Control of a Helicopter Main Rotor

    Science.gov (United States)

    Thornburgh, Robert P.; Kreshock, Andrew R.; Wilbur, Matthew L.; Sekula, Martin K.; Shen, Jinwei

    2014-01-01

    The use of continuous trailing-edge flaps (CTEFs) for primary flight control of a helicopter main rotor is studied. A practical, optimized bimorph design with Macro-Fiber Composite actuators is developed for CTEF control, and a coupled structures and computational fluid dynamics methodology is used to study the fundamental behavior of an airfoil with CTEFs. These results are used within a comprehensive rotorcraft analysis model to study the control authority requirements of the CTEFs when utilized for primary flight control of a utility class helicopter. A study of the effect of blade root pitch index (RPI) on CTEF control authority is conducted, and the impact of structural and aerodynamic model complexity on the comprehensive analysis results is presented. The results show that primary flight control using CTEFs is promising; however, a more viable option may include the control of blade RPI, as well.

  8. Anthropometric Considerations in the Modernized Main Control Room: Application to a Virtual Nuclear Power Plant Control Panel

    International Nuclear Information System (INIS)

    Yang, Chih Wei; Cheng, Tsung Chieh; Lin, Chiuhsiang Joe

    2011-01-01

    This study investigates the anthropometric considerations in the main control room (MCR) application to a virtual nuclear power plant (NPP) control panel. Influences of working postures and physical demands on the operational performance are also discussed. Finally, the present research provides a case example to illustrate the influences of anthropometric considerations on the control panel design for MCR operators by applying virtual reality (VR) technology. The MCR design primarily evolved in different countries. The datasets available is usually insufficient or inconsistent for the end users. To solve the upper mentioned problem, this study put emphasis on applying VR technology to anthropometric considerations support control panel design in the modernized MCR. Although the concept of applying VR technology on anthropometric considerations in this paper is related to the MCR in NPPs, it could be easily applied for the purposes of any type of control room in a similar manner

  9. Anthropometric Considerations in the Modernized Main Control Room: Application to a Virtual Nuclear Power Plant Control Panel

    Energy Technology Data Exchange (ETDEWEB)

    Yang, Chih Wei; Cheng, Tsung Chieh [Institute of Nuclear Energy Research, Taoyuan (China); Lin, Chiuhsiang Joe [Chung-Yuan Christian University, Chung Li (China)

    2011-08-15

    This study investigates the anthropometric considerations in the main control room (MCR) application to a virtual nuclear power plant (NPP) control panel. Influences of working postures and physical demands on the operational performance are also discussed. Finally, the present research provides a case example to illustrate the influences of anthropometric considerations on the control panel design for MCR operators by applying virtual reality (VR) technology. The MCR design primarily evolved in different countries. The datasets available is usually insufficient or inconsistent for the end users. To solve the upper mentioned problem, this study put emphasis on applying VR technology to anthropometric considerations support control panel design in the modernized MCR. Although the concept of applying VR technology on anthropometric considerations in this paper is related to the MCR in NPPs, it could be easily applied for the purposes of any type of control room in a similar manner.

  10. Pertinent spatio-temporal scale of observation to understand suspended sediment yield control factors in the Andean region: the case of the Santa River (Peru)

    Science.gov (United States)

    Morera, S. B.; Condom, T.; Vauchel, P.; Guyot, J.-L.; Galvez, C.; Crave, A.

    2013-11-01

    Hydro-sedimentology development is a great challenge in Peru due to limited data as well as sparse and confidential information. This study aimed to quantify and to understand the suspended sediment yield from the west-central Andes Mountains and to identify the main erosion-control factors and their relevance. The Tablachaca River (3132 km2) and the Santa River (6815 km2), located in two adjacent Andes catchments, showed similar statistical daily rainfall and discharge variability but large differences in specific suspended-sediment yield (SSY). In order to investigate the main erosion factors, daily water discharge and suspended sediment concentration (SSC) datasets of the Santa and Tablachaca rivers were analysed. Mining activity in specific lithologies was identified as the major factor that controls the high SSY of the Tablachaca (2204 t km2 yr-1), which is four times greater than the Santa's SSY. These results show that the analysis of control factors of regional SSY at the Andes scale should be done carefully. Indeed, spatial data at kilometric scale and also daily water discharge and SSC time series are needed to define the main erosion factors along the entire Andean range.

  11. Large screen mimic display design research for advanced main control room in nuclear power plant

    International Nuclear Information System (INIS)

    Zheng Mingguang; Yang Yanhua; Xu Jijun; Zhang Qinshun; Ning Zhonghe

    2002-01-01

    Firstly the evolution of mimic diagrams or displays used in the main control room of nuclear power plant was introduced. The active functions of mimic diagrams were analyzed on the release of operator psychological burden and pressure, the assistance of operator for the information searching, status understanding, manual actuation, correct decision making as well as the safe and reliable operation of the nuclear power plant. The importance and necessity to use the (large screen) mimic diagrams in advanced main control room of nuclear power plant, the design principle, design details and verification measures of large screen mimic display are also described

  12. Requirements to amend the main influence factors on the safety culture after fukushima accident

    International Nuclear Information System (INIS)

    Farcasiu, M.; Nitoi, M.

    2015-01-01

    The paper presents a general model that provides a framework for the safety culture assessment, creating the possibility to identify factors that can significantly influence the safety culture. The main safety culture influence factors (SCIF) used by model are the following: regulatory environment, organizational environment, worker characteristics, socio-political environment, national culture, organization history, business and technological characteristics. After the analysis of the deficiencies and weaknesses of SCIFc in evolution of the Fukushima accident, some issues that may become necessities and requirements to change and improve both the safety culture and safety of the nuclear installations were highlighted. For each influence factor were identified some requirements to amend. The results will emphasize the necesity of the human - technology - organization system assessment. Hence it was demonstrated that the safety culture results from the interaction of individuals with technology and with the organization. (authors)

  13. Colon cancer controls versus population controls in case-control studies of occupational risk factors

    DEFF Research Database (Denmark)

    Kaerlev, Linda; Lynge, Elsebeth; Sabroe, Svend

    2004-01-01

    are interchangeable with the experience for population controls. Patient controls may even be preferable from population controls under certain conditions. In this study we examine if colon cancer patients can serve as surrogates for proper population controls in case-control studies of occupational risk factors...... about occupational, medical and life style conditions. RESULTS: No statistical significant difference for educational level, medical history or smoking status was seen between the two control groups. There was evidence of a higher alcohol intake, less frequent work as a farmer and less exposure...... to pesticides among colon cancer controls. CONCLUSIONS: Use of colon cancer controls may provide valid exposure estimates in studies of many occupational risk factors for cancer, but not for studies on exposure related to farming....

  14. Operating experience with LAMPF main beam lines instrumentation and control system

    International Nuclear Information System (INIS)

    van Dyck, O.B.; Harvey, A.; Howard, H.H.; Roeder, D.L.

    1975-01-01

    Instrumentation and control (I and C) for the Los Alamos Clinton P. Anderson Meson Physics Facility (LAMPF) main beam line is based upon central computer control through remote stations which provide input and output to most devices. Operating experience shows that the ability of the computer to give high-quality graphical presentation of the measurements enhances operator performance and instrument usefulness. Experience also shows that operator efficiency degrades rapidly with increasing instrument response time, that is, with increasing delay between the time a control is changed and the result can be observed. For this reason, instrumentation upgrade includes speeding up data acquisition and display times to under 10 s. Similarly, television-viewed phosphors are being retained where possible since their instantaneous response is very useful. Other upgrading of the instrumentation system is planned to improve data accuracy, reliability, redundancy, and instrument radiation tolerance. Past experience is being applied in adding or relocating devices to simplify tuning procedures. (U.S.)

  15. Is always the family the main risk factor in Child to Parent Violence?

    Directory of Open Access Journals (Sweden)

    Rafael March Ortega

    2017-04-01

    Full Text Available Many of the programs carried out in order to intervene with Child to Parent Violence (CPV are directed mainly towards victims. The fact that family is the primary agent of socialization contributes to trying to find the reasons behind children and adolescents’ behavioral disorders in this field. Thus, many authors see CPV as a «high-risk» situation within the family in which minors are not properly treated, where there are degraded contexts, inadequate parenting styles, blurred boundaries, hostility and neglect, a pathological profile of the parents, conflicting relationships between the partner and disregard for the children who become considered as victims and tormentors at the same time. A large amount of research seems to support this point of view, but, is it true in most cases? Or, in other words: is always the family the main risk factor in Child to Parent Violence?

  16. Impact analysis of critical success factors on the benefits from statistical process control implementation

    Directory of Open Access Journals (Sweden)

    Fabiano Rodrigues Soriano

    Full Text Available Abstract The Statistical Process Control - SPC is a set of statistical techniques focused on process control, monitoring and analyzing variation causes in the quality characteristics and/or in the parameters used to control and process improvements. Implementing SPC in organizations is a complex task. The reasons for its failure are related to organizational or social factors such as lack of top management commitment and little understanding about its potential benefits. Other aspects concern technical factors such as lack of training on and understanding about the statistical techniques. The main aim of the present article is to understand the interrelations between conditioning factors associated with top management commitment (Support, SPC Training and Application, as well as to understand the relationships between these factors and the benefits associated with the implementation of the program. The Partial Least Squares Structural Equation Modeling (PLS-SEM was used in the analysis since the main goal is to establish the causal relations. A cross-section survey was used as research method to collect information of samples from Brazilian auto-parts companies, which were selected according to guides from the auto-parts industry associations. A total of 170 companies were contacted by e-mail and by phone in order to be invited to participate in the survey. However, just 93 industries agreed on participating, and only 43 answered the questionnaire. The results showed that the senior management support considerably affects the way companies develop their training programs. In turn, these trainings affect the way companies apply the techniques. Thus, it will reflect on the benefits gotten from implementing the program. It was observed that the managerial and technical aspects are closely connected to each other and that they are represented by the ratio between top management and training support. The technical aspects observed through SPC

  17. Operating experience with an on-line vibration control system for PWR main coolant pumps

    International Nuclear Information System (INIS)

    Runkel, J.; Stegemann, D.; Vortriede, A.

    1996-01-01

    The main circulation pumps are key components of nuclear power plants with pressurized water reactors, because the availability of the main circulation pumps has a direct influence on the availability and electrical output of the entire plant. The on-line automatic vibration control system ASMAS was developed for early failure detection during the normal operation of the main circulation pumps in order to avoid unexpected outages and to establish the possibility of preventive maintenance of the pumps. This system is permanently and successfully operating in three German 1300 MW el NPP's with PWR and has been successfully tested in a 350 MW el NPP with a PWR. (orig.)

  18. Operating experience with an on-line vibration control system for PWR main coolant pumps

    International Nuclear Information System (INIS)

    Runkel, J.; Stegemann, D.; Vortriede, A.

    1998-01-01

    The main circulation pumps are key components of nuclear power plants with pressurized water reactors (PWRs), because the availability of the main circulation pumps has a direct influence on the availability and electrical output of the entire plant. The on-line automatic vibration control system ASMAS was developed for early failure detection during the normal operation of the main circulation pumps in order to avoid unexpected outages and to establish the possibility of preventive maintenance of the pumps. This system is permanently and successfully operating in three German 1300 MW e1 NPP's with PWR and has been successfully tested in a 350 MW e1 NPP with a PWR. (orig.)

  19. Determination of functions of controlling drives of main executive mechanisms of mining excavators

    Science.gov (United States)

    Lagunova, Yu A.; Komissarov, A. P.; Lukashuk, O. A.

    2018-03-01

    It is shown that a special shovel is a feature of the structure of the drives of the main mechanisms (mechanisms of lifting and pressure) of career excavators with working equipment, the presence in the transfer device of a two-crank-lever mechanism of working equipment that connects the main mechanisms with the working body (bucket). In this case, the transformation of the mechanical energy parameters of the motors into energy-force parameters realized at the cutting edge of the bucket (teeth) takes place depending on the type of the kinematic scheme of the two-link-lever mechanism. The concept of “control function” defining the relationship between the parameters characterizing the position of the bucket in the face (the coordinates of the tip of the cutting edge of the bucket, the digging speed) and the required control level are introduced. These are the values of the lifting and head speeds ensuring the bucket movement along a given trajectory.

  20. Gulf of Maine - Control Points Used to Validate the Accuracies of the Interpolated Water Density Rasters

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — This feature dataset contains the control points used to validate the accuracies of the interpolated water density rasters for the Gulf of Maine. These control...

  1. Evaluation of Control and Adjustment Structures of the Shibab Main Canal Using HEC-RAS

    Directory of Open Access Journals (Sweden)

    maryam mohammadi

    2017-02-01

    simulation results of different scenarios and investigation of the effective factors onto the flow, onthe forms of charts and tables show that without management on controlling structures, it isn`t possible to appropriate of flow rate onto second class canals and traditional streams branched out main canal and also streams branched out second class canals, properly. Conclusion: The results show that the model of HEC-RAS is proper for hydraulic simulation of main canal in the irrigation and drainage network of Sistan plain. Based on the simulation results of different scenarios of this research, the mostimprovements intheobjective functionare allocated toequity and reliability indexes in the Shibab main canal with the proposed management method.

  2. Simplified Models for Analysis and Design of the Control System Main Loops of CAREM Reactor

    International Nuclear Information System (INIS)

    Etchepareborda, Andres; Flury, Celso

    2000-01-01

    The target of this work is to show a few models developed for control analysis and design of the reactor CAREM's main control loops within a broad range of power (between 40 % and 100%).By one side, it is shown the main features of a analytic model programed in MATLAB.This model is based on fitting steady state points at different power levels of the CAREM's RETRAN model.By the other side, it is shown linear models of black-box type denoting the perturbed behavior of the system for each level power point.These models are identified from temporal responses of CAREM's RETRAN model to perturbed input signals over the different steady power level points.Then the dynamics of these models are verified contrasting the temporal responses of the RETRAN model versus the responses of the MATLAB model and the identified models, in each steady power level point.Also are contrasting the frequency response of the linearization of MATLAB model versus the frequency response of the identified models, in each steady power level point.Either the MATLAB model as the identified models are good enough for the control analysis and design of the three main control loops.The MATLAB model has a few differences against the RETRAN model in the primary pressure output variable, that it must be taken into account in the design of this control loop if this model is used.The aim of these models is to represent in a satisfactory way the dynamics of the plant for a later control analysis and design of the control loops in a frequency range between 0.01 rad/seg and 0.3 rad/seg, and a power range between 40 % and 100 %

  3. Concepts of analytical user interface evaluation method for continuous work in NPP main control room

    International Nuclear Information System (INIS)

    Lee, S. J.; Heo, G. Y.; Jang, S. H.

    2003-01-01

    This paper describes a conceptual study of analytical evaluation method for computer-based user interface in the main control room of advanced nuclear power plant. User interfaces can classify them into two groups as static interface and dynamic interface. Existing evaluation and design methods of user interface have been mainly performed for the static user interface. But, it is useful for the dynamic user interface to control the complex system, and proper evaluation method for this is seldom. Therefore an evaluation method for dynamic user interface is proper for continuous works by standards of the load of cognition and the similarity of an interface

  4. RESEARCH OF THE HIGH HARMONICS INDIVIDUAL BLADE CONTROL EFFECT ON VIBRATIONS CAUSED BY THE HELICOPTER MAIN ROTOR THRUST

    Directory of Open Access Journals (Sweden)

    2016-01-01

    Full Text Available The paper presents numerical results analysis of main rotor vibration due to helicopter main rotor thrust pulsation.The calculation method, the object of research and numerical research results with the aim to reduce the amplitude of the vibrations transmitted to the hub from the helicopters main rotor by the individual blade control in azimuth by the installation angle of blades cyclic changes are set out in the article. The individual blades control law for a five-blade main rotor based on the blade frequencies is made. It allows reducing the vibration from thrust. Research takes into account the main rotor including and excluding the blade flapping motion. The minimal vibrations regime is identified.Numerical study of variable loads caused by unsteady flow around the main rotor blades at high relative speeds of flight, which transmitted to the rotor hub, is made. The scheme of a thin lifting surface and the rotor vortex theory are used for simulation of the aerodynamic loads on blades. Non - uniform loads caused by the thrust, decomposed on the blade harmonic and its overtones. The largest values of deviation from the mean amplitude thrust are received. The analysis of variable loads with a traditional control system is made. Algorithms of higher harmonics individual blade control capable of reducing the thrust pulsation under the average value of thrust are developed.Numerical research shows that individual blade control of high harmonics reduces variable loads. The necessary change in the blade installation is about ± 0,2 degree that corresponds to the maximum displacement of the additional con- trol stick is about 1 mm.To receive the overall picture is necessary to consider all six components of forces and moments. Control law with own constants will obtained for each of them. It is supposed, that each of six individual blade control laws have an impact on other components. Thus, the problem reduces to the optimization issue. The

  5. Factors influencing warfarin control in Australia and Singapore.

    Science.gov (United States)

    Bernaitis, Nijole; Ching, Chi Keong; Teo, Siew Chong; Chen, Liping; Badrick, Tony; Davey, Andrew K; Crilly, Julia; Anoopkumar-Dukie, Shailendra

    2017-09-01

    Warfarin is widely used for patients with non-valvular atrial fibrillation (NVAF). Variations in warfarin control, as measured by time in therapeutic range (TTR), have been reported across different regions and ethnicities, particularly between Western and Asian countries. However, there is limited data on comparative factors influencing warfarin control in Caucasian and Asian patients. Therefore, the aim of this study was to determine warfarin control and potential factors influencing this in patients with NVAF in Australia and Singapore. Retrospective data was collected for patients receiving warfarin for January to June 2014 in Australia and Singapore. TTR was calculated for individuals with mean patient TTR used for analysis. Possible influential factors on TTR were analysed including age, gender, concurrent co-morbidities, and concurrent medication. The mean TTR was significantly higher in Australia (82%) than Singapore (58%). At both sites, chronic kidney disease significantly lowered this TTR. Further factors influencing control were anaemia and ageWarfarin control was significantly higher in Australia compared to Singapore, however chronic kidney disease reduced control at both sites. The different levels of control in these two countries, together with patient factors further reducing control may impact on anticoagulant choice in these countries with better outcomes from warfarin in Australia compared to Singapore. Copyright © 2017 Elsevier Ltd. All rights reserved.

  6. International Organizations: the Main Factors of Emergence and Development

    Directory of Open Access Journals (Sweden)

    Lev S. Voronkov

    2015-01-01

    Full Text Available The author argues that the emergence of the first permanent intergovernmental (IIGO and non-governmental (INGO organizationsin the second half of the XIX-th century was due to common causes. He tries to justify the need to consider them not as independent objects of study, but as the phenomenon, caused by the high level of internationalization of economic life of states and of socio-economic consequences of the industrial revolution, reached in this period. The emergence of IIGOs, based on international treaty, was accompanied by establishment of a large number of INGOs operating in similar fields of human activity, which performed supplementary functions and regulated areas of cooperation and public needs, not covered by interstate agreements. The article presents the main factors that in later stages of internationalization and development of contemporary international relations gave the impetus to emergence and development of international organizations, including the military-technological revolution, that gave birth to mass destruction weapons and avalanche-like growth of the number of human and material losses during wars and military conflicts, the Cold War between world communism and world capitalism, the collapse of the colonial system and formation ofa new main contradiction of the world politics between the "Club of rich countries" and states of the "global periphery", beginning of development of regional integration processes and, finally, the emergence of global problems. The article emphasizes that both IIGOs and INGOs evolved from the supportive tools in implementation of multilateral interaction of sovereign states towards becoming an integral part of contemporary international relations, fulfilling many vital functions of modern human society and its citizens. Given the involvement of the overwhelming majority of modern sovereign states and tens of thousands of civil society organizations in activity of numerical IIGOs and INGOs

  7. Soft-Starting Power-Factor Motor Controller

    Science.gov (United States)

    Nola, F. J.

    1983-01-01

    Three-phase power-factor controller with soft start is based on earlier version that does not control starting transients. Additional components serve to turn off "run" command signal and substitute gradual startup command signal during preset startup interval. Improved controller reduces large current surge that usually accompanies starting. Controller applies power smoothly, without causing motor vibrations.

  8. PS Main Control Room (partial view)

    CERN Multimedia

    1974-01-01

    Jean-Pierre Potier (turning buttons) and Bertran Frammery (telephoning) on shift. The 26 GeV Synchrotron and later also its related machines (Linacs 1,2,3; PS-Booster; LEP-Injector Linacs and Electron-Positron Accumulator; Antiproton Accumulator, Antiproton Collector, Low Energy Antiproton Ring and more recently Antiproton Decelerator) were all controlled from the PS control room situated on the Meyrin site. The SPS and LEP were controlled from a separat control centre on the Prevessin site. In 2005 all controls were transferred to the Prevessin centre.

  9. Risk factors for pre-term birth in Iraq: a case-control study

    Directory of Open Access Journals (Sweden)

    Al-Dabbagh Samim A

    2006-04-01

    Full Text Available Abstract Background Preterm birth (PTBis a major clinical problem associated with perinatal mortality and morbidity. The aim of the present study is to identify risk factors associated with PTB in Mosul, Iraq. Methods A case-control study was conducted in Mosul, Iraq, from 1st September, 2003 to 28th February, 2004. Results A total of 200 cases of PTB and 200 controls of full-term births were screened and enrolled in the study. Forward logistic regression analysis was used in the analysis. Several significant risk associations between PTB and the following risk factors were identified: poor diet (OR = 4.33, heavy manual work (OR = 1.70, caring for domestic animals (OR = 5.06, urinary tract infection (OR = 2.85, anxiety (OR = 2.16, cervical incompetence (OR = 4.74, multiple pregnancies (OR = 7.51, direct trauma to abdomen (OR = 3.76 and abortion (OR = 6.36. Conclusion The main determinants of PTB in Iraq were low socio-economic status and factors associated with it, such as heavy manual work and caring for domestic animals, in addition to urinary tract infections and poor obstetric history.

  10. Analysis of the Main Factors Influencing Food Production in China Based on Time Series Trend Chart

    Institute of Scientific and Technical Information of China (English)

    Shuangjin; WANG; Jianying; LI

    2014-01-01

    Based on the annual sample data on food production in China since the reform and opening up,we select 8 main factors influencing the total food production( growing area,application rate of chemical fertilizer,effective irrigation area,the affected area,total machinery power,food production cost index,food production price index,financial funds for supporting agriculture,farmers and countryside),and put them into categories of material input,resources and environment,and policy factors. Using the factor analysis,we carry out the multi-angle analysis of these typical influencing factors one by one through the time series trend chart. It is found that application rate of chemical fertilizer,the growing area of food crops and drought-affected area become the key factors affecting food production. On this basis,we set forth the corresponding recommendations for improving the comprehensive food production capacity.

  11. Bone mineral density in children with acute leukemia and its associated factors in Iran: a case-control study.

    Science.gov (United States)

    Bordbar, Mohammad Reza; Haghpanah, Sezaneh; Dabbaghmanesh, Mohammad Hossein; Omrani, Gholamhossein Ranjbar; Saki, Forough

    2016-12-01

    Acute leukemia is the most common malignancy in children. We showed that low bone mass is prevalent among children with leukemia, especially in femur. Serum calcium, exercise, chemotherapy protocol, and radiotherapy are the main contributing factors. We suggest that early diagnosis and treatment of this problem could improve bone health in them. Acute leukemia is the most common malignancy in children and has been reported to be associated with low bone mass. Due to lack of sufficient data about the bone mineral density of children with leukemia in the Middle East, and inconsistencies between possible associated factors contributing to decreasing bone density in these children, we aimed to conduct a case-control study in Iran. This case-control study was conducted on 60 children with acute leukemia and 60 age- and sex-matched healthy controls. Anthropometric data, sun exposure, puberty, physical activity, and mineral biochemical parameters were assessed. Bone mineral density (BMD) was measured by dual-energy X-ray absorptiometry (DEXA). Data analysis was done by SPSS software v. 21. Serum calcium was higher in the control group (P = 0.012) while serum phosphorous, alkaline phosphatase, and serum 25(OH)D 3 were higher in children with leukemia with P values of 0.04, 0.002, and 0.036, respectively. Sun exposure and physical activity were more in healthy controls (P values children with leukemia, especially in the femoral neck. Serum calcium, physical activity, chemotherapy protocol, and radiotherapy are the main contributing factors.

  12. Eukaryotic Initiation Factor 4H Is under Transcriptional Control of p65/NF-κB

    Science.gov (United States)

    Fiume, Giuseppe; Rossi, Annalisa; de Laurentiis, Annamaria; Falcone, Cristina; Pisano, Antonio; Vecchio, Eleonora; Pontoriero, Marilena; Scala, Iris; Scialdone, Annarita; Masci, Francesca Fasanella; Mimmi, Selena; Palmieri, Camillo; Scala, Giuseppe; Quinto, Ileana

    2013-01-01

    Protein synthesis is mainly regulated at the initiation step, allowing the fast, reversible and spatial control of gene expression. Initiation of protein synthesis requires at least 13 translation initiation factors to assemble the 80S ribosomal initiation complex. Loss of translation control may result in cell malignant transformation. Here, we asked whether translational initiation factors could be regulated by NF-κB transcription factor, a major regulator of genes involved in cell proliferation, survival, and inflammatory response. We show that the p65 subunit of NF-κB activates the transcription of eIF4H gene, which is the regulatory subunit of eIF4A, the most relevant RNA helicase in translation initiation. The p65-dependent transcriptional activation of eIF4H increased the eIF4H protein content augmenting the rate of global protein synthesis. In this context, our results provide novel insights into protein synthesis regulation in response to NF-κB activation signalling, suggesting a transcription-translation coupled mechanism of control. PMID:23776612

  13. Mutual fund flows: an analysis of the main macroeconomic factors

    Directory of Open Access Journals (Sweden)

    Raphael Moses Roquete

    2015-03-01

    Full Text Available This paper analyzes whether some macroeconomic factors (country risk, IBrX volatility and Interbank Certificate of Deposit are related to mutual fund flows for the period between January 2005 and August 2014. In order to investigate whether the flow series behaved differently during this period, the Chow test was conducted for September 2008 (the month in which the Lehman Brothers investment bank collapsed. The regressions were performed and the parameters were estimated through the OLS method for both periods, the first running from January 2005 to August 2008 and the second from September 2008 to August 2014. For the period between January 2005 and August 2008, all the variables, except for the Interbank Certificate of Deposit, proved significant, at a significance level of 10%. For the subsequent period, none of the variables proved significant and the R² was very low, which may merely indicate that investors failed to analyze the main macroeconomic variables for mutual fund allocations or redemptions and simply considered other aspects, such as manager performance.

  14. COMPLIANCE AS FACTORING BUSINESS RISK MANAGEMENT: CONTROL ASPECTS

    Directory of Open Access Journals (Sweden)

    V.K. Makarovych

    2016-03-01

    Full Text Available Indetermination of modern economy conditions and the lack of theoretical knowledge gained by domestic scientists about risk in factoring business actualize the research concerning the methodology and technique of factoring companies’ risk management. The article examines compliance which is the technology innovative for Ukrainian market of factoring risk management technologies. It is determined that the compliance is the risk management process directed to free will correspondence to state, international legislation as well as to the ethics standards accepted in the field of regulated legal relations and to the traditions of business circulation to sustain the necessary regulations and standards of market behaviour, and to consolidate the image of a factoring company. Compliance risks should be understood as the risks of missed profit or losses caused by the conflicts of interests and the discrepancy of employees’ actions to internal and external standard documents. The attention is paid to the control over the compliance. The author singles out 3 kinds of the compliance control such as institutional, operational and the compliance control over the observance of conducting business professional ethics regulations which are necessary for providing of efficient management of factoring business risks. The paper shows the organizing process of factoring business compliance control (by the development of internal standard documents, a compliance program, the foundation of compliance control subdivision, monitoring of the risks cause the choice, made by management entities of a factoring company, of the management methods of risks for their business. The development of new and improvement of existed forms of compliance control organizing process help satisfy users’ information needs and requests of the risk management factoring company department. The suggestions proposed create the grounds for the transformation and improvement of factoring

  15. [Analysis of main risk factors causing foodborne diseases in food catering business].

    Science.gov (United States)

    Fan, Yong-xiang; Liu, Xiu-mei; Bao, Yi-dan

    2011-06-01

    To study main risk factors that cause foodborne diseases in food catering business. Data from references and investigations conducted in food catering units were used to establish models which based on @Risk 4.5 with Monte Carlo method referring to food handling practice model (FHPM) to make risk assessment on factors of food contamination in food catering units. The Beta-Poisson models on dose-response relationship to Salmonella (developed by WHO/FAO and United States Department of Agriculture) and Vibrio parahaemolyticus (developed by US FDA) were used in this article to analyze the dose-response relationship of pathogens. The average probability of food poisoning by consuming Salmonella contaminated cooked meat under refrigeration was 1.96 × 10(-4) which was 1/2800 of the food under non-refrigeration (the average probability of food poisoning was 0.35 at room temperature 25°C). The average probability by consuming 6 hours stored meat under room temperature was 0.11 which was 16 times of 2 hours storage (6.79 × 10(-3)). The average probability by consuming contaminated meat without fully cooking was 1.71 × 10(-4) which was 100 times of consuming fully cooked meat (1.88 × 10(-6)). The probability growth of food poisoning by consuming Vibrio parahaemolyticus contaminated fresh seafood was proportional with contamination level and prevalence. The primary contamination level, storage temperature and time, cooking process and cross contamination are important factors of catering food safety.

  16. Sensitivity Analysis on Fire Modeling of Main Control Board Fire Using Fire Dynamics Simulator

    International Nuclear Information System (INIS)

    Kang, Dae Il; Lim, Ho Gon

    2015-01-01

    In this study, sensitivity analyses for an MCB fire were performed to identify the effects on the MCR forced abandonment time according to the changes of height and number for fire initiation places. Hanul Unit 3 NPP was selected as a reference plant for this study. In this study, sensitivity analyses for an MCB fire were performed to identify the effects on the MCR forced abandonment time according to the changes of height and number of fire initiation places. A main control board (MCB) fire can cause a forced main control room (MCR) abandonment of the operators as well as the function failures or spurious operations of the control and instrumentation-related components. If the MCR cannot be habitable, a safe shutdown from outside the MCR can be achieved and maintained at an alternate shutdown panel independent from the MCR. When the fire modeling for an electrical cabinet such as an MCB was performed, its many input parameters can affect the fire simulation results. This study results showed that the decrease in the height of fire ignition place and the use of single fire ignition place in fire modeling for the propagating fire shortened MCR abandonment time

  17. Sensitivity Analysis on Fire Modeling of Main Control Board Fire Using Fire Dynamics Simulator

    Energy Technology Data Exchange (ETDEWEB)

    Kang, Dae Il; Lim, Ho Gon [Korea Atomic Energy Research Institute, Daejeon (Korea, Republic of)

    2015-10-15

    In this study, sensitivity analyses for an MCB fire were performed to identify the effects on the MCR forced abandonment time according to the changes of height and number for fire initiation places. Hanul Unit 3 NPP was selected as a reference plant for this study. In this study, sensitivity analyses for an MCB fire were performed to identify the effects on the MCR forced abandonment time according to the changes of height and number of fire initiation places. A main control board (MCB) fire can cause a forced main control room (MCR) abandonment of the operators as well as the function failures or spurious operations of the control and instrumentation-related components. If the MCR cannot be habitable, a safe shutdown from outside the MCR can be achieved and maintained at an alternate shutdown panel independent from the MCR. When the fire modeling for an electrical cabinet such as an MCB was performed, its many input parameters can affect the fire simulation results. This study results showed that the decrease in the height of fire ignition place and the use of single fire ignition place in fire modeling for the propagating fire shortened MCR abandonment time.

  18. Dietary pattern and lifestyle factors in asthma control

    Directory of Open Access Journals (Sweden)

    Mohammed Noufal Poongadan

    2016-01-01

    Full Text Available Background: The prevalence of asthma in adults varied from 0.96% to 11.03% while in children ranged from 2.3% to 11.9% in India. A number of factors including genetic predisposition, environment, and lifestyle factors including dietary habits influence the development and expression of asthma. The goal of asthma treatment is to achieve and maintain clinical control, which can be achieved in a majority of patients with pharmacologic intervention strategy. Objective: To assess the role of diet and lifestyle factors in asthma control in Indian population. Materials and Methods: Diagnosed asthma patients (aged 12-40 years were enrolled from the outpatient clinics. All patients were followed up and reassessed after 4 weeks with asthma control test (ACT and dietary and lifestyle questionnaire. The assessment of dietary pattern was performed by food frequency questionnaire (Nordic Nutrition Recommendations-Danish Physical Activity Questionnaire. The lifestyle factor included body mass index, smoking status, tobacco chewing, alcohol consumption, duration of travel (h/week, mental stress (visual analog scale: 0-10, sports activity - h/day, television (TV watching/video games - h/day, duration of sleep - h/day. Results: Seventy-five asthma patients (43 males and 32 females were divided into three groups according to ACT, 18 (24% patients in poorly-controlled asthma, 35 (46.7% in well-controlled asthma, and 22 (29.3% patients with totally-controlled asthma. Increased consumption of vegetables and cereals in patients with total-controlled asthma while increased consumption of sugar, nonvegetarian, fast food, salted and fried snacks in patients with poorly-controlled asthma. Poorly-controlled asthma had the highest duration of watching TV and sleep and least duration of travel and sports, though the results failed to reach statistical significance. Conclusion: The dietary and lifestyle factors too contribute to degree of control of asthma in India.

  19. Assessment of destabilizing factor for automatic control systems in propulsion systems of mechatronic and maritime transport objects

    Science.gov (United States)

    Zhilenkov, A. A.; Kapitonov, A. A.

    2017-10-01

    It is known that many of today’s ships and vessels have a shaft generator as a part of their power plants. Modern automatic control systems used in the world’s fleet do not enable their shaft generators to operate in parallel with the main diesel generators for long-term sustenance of the total load of the ship network. On the other hand, according to our calculations and experiments, a shaft generator operated in parallel with the main power plant helps save at least 10% of fuel while making the power system of the ship more efficient, reliable, and eco-friendly. The fouling and corrosion of the propeller as well as the weather conditions of navigation affect its modulus of resistance. It changes the free component of the transient process of shaft generator stress frequency changes in transient processes. While the shaft generator and the diesel generator of the ship power plant are paralleled, there emerges an angle between their EMF. This results in equalizing currents generated between them. The altering torque in the drive-shaft line—propeller system causes torsional fluctuations of the ship shaft line. To compensate for the effect of destabilizing factors and torsional fluctuations of the shaft line on the dynamic characteristics of the transient process that alters the RPM of the main engine, sliding mode controls can be used. To synthesize such a control, one has to evaluate the effect of destabilizing factors.

  20. Evaluation for the habitability of the main control room and the performance of the smoke control system at NPP

    International Nuclear Information System (INIS)

    Ji, M. H.; Hong, S. R.; Sung, C. K.

    2002-01-01

    In addition to the indoor air conditioning, the habitability of the main control room for the operators at Nuclear Power Plants (NPP) has to be ensured with a strict design requirements to protect the workers from the radiation exposure, hazardous chemicals, and the smoke with toxic combustion products. With this context, the internal pressure of the control room envelope shall be sustained at slightly higher pressure than the atmospheric pressure. At this paper, the internal pressure of the control room envelope was analyzed by use of the evaluation program, CONTANW that was developed by the NIST. On the basis of design values, the performance status of the smoke control system was also checked by the program, CFAST that was released by the NIST to confirm the dynamic smoke behaviors

  1. Human factors challenges for advanced process control

    International Nuclear Information System (INIS)

    Stubler, W.F.; O'Hara, J..M.

    1996-01-01

    New human-system interface technologies provide opportunities for improving operator and plant performance. However, if these technologies are not properly implemented, they may introduce new challenges to performance and safety. This paper reports the results from a survey of human factors considerations that arise in the implementation of advanced human-system interface technologies in process control and other complex systems. General trends were identified for several areas based on a review of technical literature and a combination of interviews and site visits with process control organizations. Human factors considerations are discussed for two of these areas, automation and controls

  2. Partial Least Squares Regression for Determining the Control Factors for Runoff and Suspended Sediment Yield during Rainfall Events

    Directory of Open Access Journals (Sweden)

    Nufang Fang

    2015-07-01

    Full Text Available Multivariate statistics are commonly used to identify the factors that control the dynamics of runoff or sediment yields during hydrological processes. However, one issue with the use of conventional statistical methods to address relationships between variables and runoff or sediment yield is multicollinearity. The main objectives of this study were to apply a method for effectively identifying runoff and sediment control factors during hydrological processes and apply that method to a case study. The method combines the clustering approach and partial least squares regression (PLSR models. The case study was conducted in a mountainous watershed in the Three Gorges Area. A total of 29 flood events in three hydrological years in areas with different land uses were obtained. In total, fourteen related variables were separated from hydrographs using the classical hydrograph separation method. Twenty-nine rainfall events were classified into two rainfall regimes (heavy Rainfall Regime I and moderate Rainfall Regime II based on rainfall characteristics and K-means clustering. Four separate PLSR models were constructed to identify the main variables that control runoff and sediment yield for the two rainfall regimes. For Rainfall Regime I, the dominant first-order factors affecting the changes in sediment yield in our study were all of the four rainfall-related variables, flood peak discharge, maximum flood suspended sediment concentration, runoff, and the percentages of forest and farmland. For Rainfall Regime II, antecedent condition-related variables have more effects on both runoff and sediment yield than in Rainfall Regime I. The results suggest that the different control factors of the two rainfall regimes are determined by the rainfall characteristics and thus different runoff mechanisms.

  3. Service provision patterns by main diagnoses and characteristics of patients.

    Science.gov (United States)

    Brennan, D S; Spencer, A J; Szuster, F S

    2000-06-01

    Service provision patterns may be influenced not only by clinical oral health status leading to a diagnosis and treatment plan, but also by other variables such as patient characteristics. The main aim of this study was to investigate whether associations between services provided and patient factors would persist after controlling for the main presenting diagnosis or condition. A random sample of dentists surveyed in 1993-94 provided a response rate of 74%. Private general practitioners recorded service provision data from logs of 1-2 typical days of practice. Caries (26.5%) was the most prevalent diagnosis, followed by recall/maintenance care (19.0%), pulpal/periapical infection (10.9%), and failed restorations (10.4%). Diagnoses were associated with variation in the percentage of patients receiving services in main areas of service, and also with insurance status, sex and age distributions of patients, and type of visit (chi-square; Pservices indicated statistically significant associations with patient characteristics and diagnosis categories. Controlling for diagnosis, uninsured patients and those visiting for emergencies had less favourable service patterns (e.g., higher odds of extractions, but lower odds of preventive and crown and bridge services) compared to patients who had dental insurance or visited for check-ups or other non-emergency dental problems. The influence of these factors on services provided has implications of public health importance in terms of appropriateness of care and social inequality.

  4. The frequency of bottle feeding as the main factor of baby bottle tooth decay syndrome

    Directory of Open Access Journals (Sweden)

    Mochamad Fahlevi Rizal

    2010-03-01

    Full Text Available Background: Dental caries remains as main problem in Indonesia and its prevalence is high (90.05%. However, there is no appropriate data that can be used to analyze dental caries in toddlers, especially baby bottle tooth decay syndrome (BBTD, though the number of BBTD cases is high in some pediatric dental clinics (90% of patients visiting the clinics. Even though some factors have already been considered to be the risk factor of BBTD, the main risk factor of BBTD is still unknown, especially BBTD in Indonesia. Purpose: This research was aimed to obtain data relating with bottle-feeding habit in 3-5 year old children in Indonesia and its caries risk. Method: The study was an observational research conducted with clinical examination through caries status (deft of each child deserved by pediatric dentists and through questionnaire distributed to parents to examine the risk factor of BBTD. Observation was conducted on 62 children in the range of age 3 to 5 years old with bottle-feeding habit. Result: The results revealed that status of caries was various. The data showed that the frequency of bottle feeding more than twice could trigger BBTD 2.27 times higher than other factors such as the use of bottle feeding as a pacifier prior sleeping, the period of bottle-feeding, and the breast-feeding experience. Conclusion: though milk as subtract can possibly become a factor triggering caries, the frequency of bottle-feeding is highly considered as main factor. Since it could modulated the bacterial colonization on dental surface, which affects its virulence.Latar belakang: Karies masih menjadi masalah utama di Indonesia. Dalam praktek sehari-hari prevalensi karies masih sangat tinggi (90.05%. Belum ada data yang memadai dalam penelaahan karies yang spesifik pada anak balita selama ini khususnya kasus sindroma karies botol (SKB sementara itu kasus SKB ditemukan sangat tinggi di beberapa klinik gigi anak (90% dari jumlah pasien yang datang ke klinik

  5. The effects of contingency factors on management control systems: an empirical study at CERN

    CERN Document Server

    Paaso, Ilkka

    Contingency theory and management control systems research offer avenues for investigating how contextual factors in organizations affect performance. This quantitative case study investigates how the context of CERN internal services influences the performance consciousness of functional service managers. A literature review recognized four contingency factors relevant for performance consciousness: interdependence, scope, standardization and variation. Data from these factors was measured empirically using a cross-sectional electronic survey and supplemented by data gathered from CERN internal documentation. A quantitative analysis of the data was performed using structural equation modelling. The main findings were congruent with existing literature indicating that a.) high interdependence between work units is associated with decreased variation, increased standardization and increased performance consciousness. b.) high scope is related to increased variation and decreased standardization. Overall, a bet...

  6. Diet-Related Risk Factors for Leprosy: A Case-Control Study

    Science.gov (United States)

    Wagenaar, Inge; van Muiden, Lisanne; Alam, Khorshed; Bowers, Robert; Hossain, Md. Anwar; Kispotta, Kolpona; Richardus, Jan Hendrik

    2015-01-01

    Background Food shortage was associated with leprosy in two recent studies investigating the relation between socioeconomic factors and leprosy. Inadequate intake of nutrients due to food shortage may affect the immune system and influence the progression of infection to clinical leprosy. We aimed to identify possible differences in dietary intake between recently diagnosed leprosy patients and control subjects. Methods In a leprosy endemic area of Bangladesh, newly diagnosed leprosy patients and control subjects were interviewed about their socioeconomic situation, health and diet. Dietary intakes were recorded with a 24-hour recall, from which a Dietary Diversity Score (DDS) was calculated. Body Mass Index (BMI) was calculated and Household Food Insecurity Access Scale (HFIAS) was filled out for every participant. Using logistic regression, a univariate, block wise multivariate, and an integrated analysis were carried out. Results 52 leprosy cases and 100 control subjects were included. Food shortage was more common, dietary diversity was lower and household food insecurity was higher in the patient group. Patients consumed significantly less items from the DDS food groups ‘Meat and fish’ and ‘Other fruits and vegetables.’ Lower food expenditure per capita, lower BMI, lower DDS and absence of household food stocks are the main factors associated with an increased risk of having leprosy. Conclusion Low income families have only little money to spend on food and consequently have a low intake of highly nutritious non-rice foods such as meat, fish, milk, eggs, fruits and vegetables. Development of clinical leprosy could be explained by deficiencies of the nutrients that these foods normally provide. PMID:25965879

  7. A Study on Large Display Panel Design for the Countermeasures against Team Errors within the Main Control Room of APR-1400

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Sa Kil; Lee, Yong Hee [Korea Atomic Energy Research Institute, Daejeon (Korea, Republic of)

    2015-10-15

    The personal aspect of human errors has been mainly overcome by virtue of the education and training. However, in the system aspect, the education and training system needs to be reconsidered for more effective reduction of human errors affected from various systems hazards. Traditionally the education and training systems are mainly not focused on team skills such as communication, situational awareness, and coordination, etc. but individual knowledge, skill, and attitude. However, the team factor is one of the crucial issues to reduce the human errors in most industries. In this study, we identify the emerging types of team errors, especially, in digitalized control room of nuclear power plants such as the APR-1400 main control room. Most works in nuclear industry are to be performed by a team of more than two persons. Even though the individual errors can be detected and recovered by the qualified others and/or the well trained team, it is rather seldom that the errors by team could be easily detected and properly recovered by the team itself. Note that the team is defined as two or more people who are appropriately interacting with each other, and the team is a dependent aggregate, which accomplishes a valuable goal. Team error is one of the typical organizational errors that may occur during performing operations in nuclear power plants. The large display panel is a representative feature of digitalized control room. As a group-view display, the large display panel provides plant overview to the operators. However, in terms of team performance and team errors, the large display panel is on a discussion board still because the large display panel was designed just a concept of passive display. In this study, we will propose revised large display panel which is integrated with several alternative interfaces against feasible team errors.

  8. A Study on Large Display Panel Design for the Countermeasures against Team Errors within the Main Control Room of APR-1400

    International Nuclear Information System (INIS)

    Kim, Sa Kil; Lee, Yong Hee

    2015-01-01

    The personal aspect of human errors has been mainly overcome by virtue of the education and training. However, in the system aspect, the education and training system needs to be reconsidered for more effective reduction of human errors affected from various systems hazards. Traditionally the education and training systems are mainly not focused on team skills such as communication, situational awareness, and coordination, etc. but individual knowledge, skill, and attitude. However, the team factor is one of the crucial issues to reduce the human errors in most industries. In this study, we identify the emerging types of team errors, especially, in digitalized control room of nuclear power plants such as the APR-1400 main control room. Most works in nuclear industry are to be performed by a team of more than two persons. Even though the individual errors can be detected and recovered by the qualified others and/or the well trained team, it is rather seldom that the errors by team could be easily detected and properly recovered by the team itself. Note that the team is defined as two or more people who are appropriately interacting with each other, and the team is a dependent aggregate, which accomplishes a valuable goal. Team error is one of the typical organizational errors that may occur during performing operations in nuclear power plants. The large display panel is a representative feature of digitalized control room. As a group-view display, the large display panel provides plant overview to the operators. However, in terms of team performance and team errors, the large display panel is on a discussion board still because the large display panel was designed just a concept of passive display. In this study, we will propose revised large display panel which is integrated with several alternative interfaces against feasible team errors

  9. 76 FR 35130 - Pipeline Safety: Control Room Management/Human Factors

    Science.gov (United States)

    2011-06-16

    ...: Control Room Management/Human Factors AGENCY: Pipeline and Hazardous Materials Safety Administration... the Control Room Management/Human Factors regulations in order to realize the safety benefits sooner... FR 5536). By this amendment to the Control Room Management/Human Factors (CRM) rule, an operator must...

  10. Risk factors associated with lipomyelomeningocele: a case-control study.

    Science.gov (United States)

    Esmaeili, Arash; Hanaei, Sara; Fadakar, Kaveh; Dadkhah, Sahar; Arjipour, Mahdi; Habibi, Zohreh; Nejat, Farideh; El Khashab, Mostafa

    2013-01-01

    In general, it seems that both genetic and environmental factors play important roles in the induction of neural tube defects. Lipomyelomeningocele (LipoMMC) is a rather common type of closed neural tube defect, but only limited studies have investigated the potential risk factors of this anomaly. Therefore, the purpose of this case-control study was to investigate the risk factors involved in LipoMMC formation. Various risk factors were evaluated in 35 children between 1 month and 10 years of age with LipoMMC in a hospital-based case-control study. The 2 control arms consisted of 35 children with myelomeningocele (MMC group) and 35 children with congenital anomalies other than central nervous system problems (control group). All groups were matched for age and visited the same hospital. A structured questionnaire was used for the collection of all data, including the mothers' weight and height during pregnancy, education, reproductive history, previous abortions, and socioeconomic status, as well as the parents' consanguinity and family history of the same anomalies. Univariate analysis of the children with LipoMMC compared to the control group showed that the use of periconceptional folic acid supplementation was significantly lower in the MMC and LipoMMC groups compared to the control group. In addition, comparison of the MMC and control groups revealed statistically significant differences regarding the use of folic acid and maternal obesity. In multivariate analysis, use of folic acid in the periconceptional period and during the first trimester was an independent risk factor for LipoMMC and MMC. Furthermore, maternal obesity was a significantly positive risk factor for MMC. The probable risk factors for LipoMMC were investigated in this case-control study. Consumption of folic acid in the periconceptional period and during the first trimester is an independent protective factor against LipoMMC. It seems that larger studies are needed to examine other possible

  11. [A case-control study of factors associated with repeat teen pregnancy based on a sample from a university maternity hospital].

    Science.gov (United States)

    Silva, Andréa de Albuquerque Arruda; Coutinho, Isabela C; Katz, Leila; Souza, Alex Sandro Rolland

    2013-03-01

    Repeat teen pregnancy is a frequent issue and is considered an aggravating factor for increased maternal and fetal morbidity and social problems. The aim of the study was to identify factors associated with repeat teen pregnancy. A case-control study was conducted in 90 postpartum adolescents with more than one pregnancy (cases) and 90 adult women with a history of only one pregnancy during adolescence (controls). Statistical analysis used hierarchical logistic regression with 5% significance. Early sexual initiation (pregnancy (pregnancy, while partner change was inversely associated. Repeat teen pregnancy was mainly associated with reproductive and socioeconomic factors. Partner change appeared as a protective factor. Measures should be adopted during the postpartum period of teenage mothers in order to avoid repeat pregnancy.

  12. Main factors of efficiency of automated radiographic complex

    International Nuclear Information System (INIS)

    Akopov, V.S.; Voronin, S.A.; Grachev, A.V.; Golenishchev, I.A.; Majorov, A.N.; Meshalkin, I.A.

    1978-01-01

    The amount of work providing an assessment of the efficiency of a complex for automatized radiographic control is considered. The technique involves four stages. An analysis was performed to ascertain the efficiency of control of flaw detectability with regard to each of the stages of radiographic control. The relationships used in determining control efficiency and cited in the paper serve as a foundation for optimizing the technical parameters of the devices of the automatized complex and for creating calculation methods for generalized assessments of the efficiency of radiographic control

  13. Human factors survey of advanced instrumentation and controls

    International Nuclear Information System (INIS)

    Carter, R.J.

    1989-01-01

    A survey oriented towards identifying the human factors issues in regard to the use of advanced instrumentation and controls (I ampersand C) in the nuclear industry was conducted. A number of United States (US) and Canadian nuclear vendors and utilities were participants in the survey. Human factors items, subsumed under the categories of computer-generated displays (CGD), controls, organizational support, training, and related topics, were discussed. The survey found the industry to be concerned about the human factors issues related to the implementation of advanced I ampersand C. Fifteen potential human factors problems were identified. They include: the need for an advanced I ampersand C guideline equivalent to NUREG-0700; a role change in the control room from operator to supervisor; information overload; adequacy of existing training technology for advanced I ampersand C; and operator acceptance and trust. 11 refs., 1 tab

  14. Rock avalanche occurrence in the San Juan province (Argentina): an analysis of their spatial distribution and main forcing factors

    Science.gov (United States)

    Penna, Ivanna; Tonini, Marj; Vega Orozco, Carmen D.; Longchamp, Céline; Derron, Marc-Henri; Jaboyedoff, Michel

    2013-04-01

    Rock avalanches are frequent phenomena in the Argentinean Andes and a particular high concentration of these events is observed in the Northwest (~25°S) and in the Central Andes from 30°S until the transition with the Patagonian Andes (~38°S). Tectonic deformation and seismicity are generally proposed as main driving factors, with weather and lithologic conditions playing a subordinate role. From 28°S to 33°S, the subhorizontal subduction of the Nazca plate drives higher shortening rates than in the surrounding areas, and an intense seismicity. Main morphotectonic units in this regions are the Cordillera and Precordillera, separated by the Barreal-Calingasta depression. In the southern central part of the flat subduction area (30°30'°-32°30'S), it is observed high valley incision and maximum local relief of 2900 m, while in the Precordillera main fluvial courses developed in the inter-thrust valleys, where local relief is up to 2400 m. In both mountain ranges, we recognized 34 rock avalanches deposits with volumes up to 0.3 km3. There is no apparent lithologic control on detachments, which involved sedimentary, volcanic and granite rocks, even though ~20% of them were favored by layering orientation. However, about 50% of the inventoried rock avalanches with the greatest volumes, developed along tectonic structures or less than 1 km far from them. The main objective of the present study is to explore the spatial distribution of rock avalanche deposits, and compare it with the instrumental seismicity and landscape conditions by means of statistical tools (e.g. exploratory data analyses, Ripley's K-function). Those analyses allow to highlight the spatial correlation between the geological events. Moreover, to visually display the detected cluster spatial patterns we elaborated kernel density maps. Our findings revealed that most of the rock avalanches show a high spatial aggregation mainly between 31°20'S-31°50'S. Main concentration of bedrock landslides

  15. Investigation of the impact of main control room digitalization on operators cognitive reliability in nuclear power plants.

    Science.gov (United States)

    Zhou, Yong; Mu, Haiying; Jiang, Jianjun; Zhang, Li

    2012-01-01

    Currently, there is a trend in nuclear power plants (NPPs) toward introducing digital and computer technologies into main control rooms (MCRs). Safe generation of electric power in NPPs requires reliable performance of cognitive tasks such as fault detection, diagnosis, and response planning. The digitalization of MCRs has dramatically changed the whole operating environment, and the ways operators interact with the plant systems. If the design and implementation of the digital technology is incompatible with operators' cognitive characteristics, it may have negative effects on operators' cognitive reliability. Firstly, on the basis of three essential prerequisites for successful cognitive tasks, a causal model is constructed to reveal the typical human performance issues arising from digitalization. The cognitive mechanisms which they impact cognitive reliability are analyzed in detail. Then, Bayesian inference is used to quantify and prioritize the influences of these factors. It suggests that interface management and unbalanced workload distribution have more significant impacts on operators' cognitive reliability.

  16. Canine diabetes mellitus risk factors: A matched case-control study.

    Science.gov (United States)

    Pöppl, Alan Gomes; de Carvalho, Guilherme Luiz Carvalho; Vivian, Itatiele Farias; Corbellini, Luis Gustavo; González, Félix Hilário Díaz

    2017-10-01

    Different subtypes of canine diabetes mellitus (CDM) have been described based on their aetiopathogenesis. Therefore, manifold risk factors may be involved in CDM development. This study aims to investigate canine diabetes mellitus risk factors. Owners of 110 diabetic dogs and 136 healthy controls matched by breed, sex, and age were interviewed concerning aspects related to diet, weight, physical activity, oral health, reproductive history, pancreatitis, and exposure to exogenous glucocorticoids. Two multivariate multivariable statistical models were created: The UMod included males and females without variables related to oestrous cycle, while the FMod included only females with all analysed variables. In the UMod, "Not exclusively commercial diet" (OR 4.86, 95%CI 2.2-10.7, Pdiet" (OR 4.14, 95%CI 1.3-12.7, P=0.01), "Table scraps abuse" (OR 3.62, 95%CI 1.1-12.2, P=0.03), "Overweight" (OR 3.91, 95%CI 1.2-12.6, P=0.02), and "Dioestrus" (OR 5.53, 95%CI 1.9-16.3, P=0.002) were statistically significant. The findings in this study support feeding not exclusively balanced commercial dog food, overweight, treats abuse, and diestrus, as main CDM risk factors. Moreover, those results give subside for preventive care studies against CDM development. Copyright © 2017 Elsevier Ltd. All rights reserved.

  17. Main factors causing intergranular and quasi-cleavage fractures at hydrogen-induced cracking in tempered martensitic steels

    Science.gov (United States)

    Kurokawa, Ami; Doshida, Tomoki; Hagihara, Yukito; Suzuki, Hiroshi; Takai, Kenichi

    2018-05-01

    Though intergranular (IG) and quasi-cleavage (QC) fractures have been widely recognized as typical fracture modes of the hydrogen-induced cracking in high-strength steels, the main factor has been unclarified yet. In the present study, the hydrogen content dependence on the main factor causing hydrogen-induced cracking has been examined through the fracture mode transition from QC to IG at the crack initiation site in the tempered martensitic steels. Two kinds of tempered martensitic steels were prepared to change the cohesive force due to the different precipitation states of Fe3C on the prior γ grain boundaries. A high amount of Si (H-Si) steel has a small amount of Fe3C on the prior austenite grain boundaries. Whereas, a low amount of Si (L-Si) steel has a large amount of Fe3C sheets on the grain boundaries. The fracture modes and initiations were observed using FE-SEM (Field Emission-Scanning Electron Microscope). The crack initiation sites of the H-Si steel were QC fracture at the notch tip under various hydrogen contents. While the crack initiation of the L-Si steel change from QC fracture at the notch tip to QC and IG fractures from approximately 10 µm ahead of the notch tip as increasing in hydrogen content. For L-Si steels, two possibilities are considered that the QC or IG fracture occurred firstly, or the QC and IG fractures occurred simultaneously. Furthermore, the principal stress and equivalent plastic strain distributions near the notch tip were calculated with FEM (Finite Element Method) analysis. The plastic strain was the maximum at the notch tip and the principle stress was the maximum at approximately 10 µm from the notch tip. The position of the initiation of QC and IG fracture observed using FE-SEM corresponds to the position of maximum strain and stress obtained with FEM, respectively. These findings indicate that the main factors causing hydrogen-induced cracking are different between QC and IG fractures.

  18. Assessing mental workload and situation awareness in the evaluation of computerized procedures in the main control room

    Energy Technology Data Exchange (ETDEWEB)

    Yang, Chih-Wei, E-mail: yangcw@iner.gov.tw [Institute of Nuclear Energy Research, 1000, Wenhua Rd., Jiaan Village, Longtan Township, Taoyuan County 32546, Taiwan (China); Yang, Li-Chen; Cheng, Tsung-Chieh [Institute of Nuclear Energy Research, 1000, Wenhua Rd., Jiaan Village, Longtan Township, Taoyuan County 32546, Taiwan (China); Jou, Yung-Tsan; Chiou, Shian-Wei [Department of Industrial Engineering, Chung-Yuan Christian University, 200, Chung Pei Rd., Chung-Li 32023, Taiwan (China)

    2012-09-15

    Highlights: Black-Right-Pointing-Pointer This study investigates procedure types' effects on operators' performance. Black-Right-Pointing-Pointer The computer-based procedure is suggested to be implemented in the main control room. Black-Right-Pointing-Pointer The computer-based procedure brings lowest mental workload. Black-Right-Pointing-Pointer And it also generates fewer error of omission, and the highest situation awareness. Black-Right-Pointing-Pointer The shift supervisor has the highest workload and the lowest situation awareness. - Abstract: Computerized procedure (CP) system has been developed in nuclear power plant (NPP) instrumentation and control (I and C) system. The system may include normal operating procedures (OPs), abnormal operating procedures (AOPs), alarm response procedures (ARPs), surveillance test procedures (STPs) and/or emergency operating procedures (EOPs). While there are many ways to evaluate computerized procedures design, the user's mental workload and situation awareness (SA) are particularly important considerations in the supervisory control of safety-critical systems. Users' mental workload and situation awareness may be influenced by human factor issues relating to computerized procedures, e.g., level of automation, dealing with (partially) unavailable I and C, switching to back-up system (e.g., paper-based procedures). Some of the positive impacts of CPs on operator performance include the following: tasks can be performed more quickly; overall workload can be reduced; cognitive workload can be minimized; fewer errors may be made in transitioning through or between procedures. However, various challenges have also been identified with CP systems. These should be addressed in the design and implementation of CPs where they are applicable. For example, narrower 'field of view' provided by CP systems than with paper-based procedures could reduce crew communications and crewmember awareness of the

  19. Assessing mental workload and situation awareness in the evaluation of computerized procedures in the main control room

    International Nuclear Information System (INIS)

    Yang, Chih-Wei; Yang, Li-Chen; Cheng, Tsung-Chieh; Jou, Yung-Tsan; Chiou, Shian-Wei

    2012-01-01

    Highlights: ► This study investigates procedure types’ effects on operators’ performance. ► The computer-based procedure is suggested to be implemented in the main control room. ► The computer-based procedure brings lowest mental workload. ► And it also generates fewer error of omission, and the highest situation awareness. ► The shift supervisor has the highest workload and the lowest situation awareness. - Abstract: Computerized procedure (CP) system has been developed in nuclear power plant (NPP) instrumentation and control (I and C) system. The system may include normal operating procedures (OPs), abnormal operating procedures (AOPs), alarm response procedures (ARPs), surveillance test procedures (STPs) and/or emergency operating procedures (EOPs). While there are many ways to evaluate computerized procedures design, the user's mental workload and situation awareness (SA) are particularly important considerations in the supervisory control of safety-critical systems. Users’ mental workload and situation awareness may be influenced by human factor issues relating to computerized procedures, e.g., level of automation, dealing with (partially) unavailable I and C, switching to back-up system (e.g., paper-based procedures). Some of the positive impacts of CPs on operator performance include the following: tasks can be performed more quickly; overall workload can be reduced; cognitive workload can be minimized; fewer errors may be made in transitioning through or between procedures. However, various challenges have also been identified with CP systems. These should be addressed in the design and implementation of CPs where they are applicable. For example, narrower “field of view” provided by CP systems than with paper-based procedures could reduce crew communications and crewmember awareness of the status and progress through the procedure. Based on a human factors experiment in which each participant monitored and controlled multiple simulated

  20. Burning mouth syndrome and associated factors: A case-control retrospective study.

    Science.gov (United States)

    Chimenos-Küstner, Eduardo; de Luca-Monasterios, Fiorella; Schemel-Suárez, Mayra; Rodríguez de Rivera-Campillo, María E; Pérez-Pérez, Alejandro M; López-López, José

    2017-02-23

    Burning mouth syndrome (BMS) can be defined as burning pain or dysesthesia on the tongue and/or other sites of the oral mucosa without a causative identifiable lesion. The discomfort is usually of daily recurrence, with a higher incidence among people aged 50 to 60 years, affecting mostly the female sex and diminishing their quality of life. The aim of this study was to evaluate the association between several pathogenic factors and burning mouth syndrome. 736 medical records of patients diagnosed of burning mouth syndrome and 132 medical records for the control group were studied retrospectively. The study time span was from January 1990 to December 2014. The protocol included: sex, age, type of oral discomfort and location, among other factors. Analysis of the association between pathogenic factors and BMS diagnosis revealed that only 3 factors showed a statistically significant association: triggers (P=.003), parafunctional habits (P=.006), and oral hygiene (P=.012). There were neither statistically significant differences in BMS incidence between sex groups (P=.408) nor association of BMS with the pathogenic factors of substance abuse (P=.915), systemic pathology (P=.685), and dietary habits (P=.904). Parafunctional habits like bruxism and abnormal movements of tongue and lips can explain the BMS main symptomatology. Psychological aspects and systemic factors should be always considered. As a multifactorial disorder, the treatment of BMS should be executed in a holistic way. Copyright © 2016 Elsevier España, S.L.U. All rights reserved.

  1. What factors play a role in preventing self-immolation?Results from a case-control study in Iran

    Directory of Open Access Journals (Sweden)

    Hosein Karim

    2015-07-01

    Full Text Available Abstract: Background: To investigate factors related to prevention of self-immolation in west of Iran. Methods: In a case-control study, 30 consecutive cases of deliberate self-inflicted burns admitted to the regional burn center (Imam Khomeini hospital in Kermanshah province, Iran were compared with controls selected from the community and matched by sex, age,district-county of residence, and rural vs urban living environment. The following characteristics relevant to preventing self immolation were collected from all cases and controls: main domestic fuel used in the household, awareness about complications of burn injuries, and use of counseling services. Results: Descriptive analyses revealed that kerosene was the main domestic fuel in the household for 83% of cases. Not surprisingly, the main means of self-immolation in 93% of the patients was kerosene, with other fuels such as petrol and domestic gas used in remaining cases. The majority of cases and controls were aware of the potential complications of burn injuries. Use of counseling services was more common in controls. Conclusions: All three aspects of preventing self-immolation – having kerosene and other fuels in the home, being aware of the complications of burn injuries, and using counseling services were present in both the cases and controls. This suggests a large portion of residents in rural Iran are potential self-immolation victims. Increasing preventive strategies may reduce risk of suicide by self-immolation.

  2. Salinity as the main factor structuring small-bodied fish assemblages in hydrologically altered Mediterranean coastal lagoons

    Directory of Open Access Journals (Sweden)

    Sílvia Rodríguez-Climent

    2013-03-01

    Full Text Available In the Ebro Delta coastal lagoons, one of the main anthropogenic pressures is the artificial freshwater input. Each coastal lagoon has different water management schemes causing profound changes in its physicochemical characteristics. The main objective of this water management is to favour some bird species with interest either for conservation or hunting activities. The present study assesses the influence of hydrological alteration on the fish assemblages of three coastal lagoons in the Ebro Delta. The small-bodied fish fauna was mainly composed of five families: Gobiidae, Poecilidae, Cyprinodontidae, Atherinidae and Mugilidae. Salinity was found to be the main factor structuring fish community in the lagoons. The dominant species was the common goby (Pomatochistus microps when the lagoons reached higher salinity values, whereas the invasive eastern mosquitofish (Gambusia holbrooki dominated during the period of higher freshwater inputs. The juveniles of the family Mugilidae showed low catch per unit effort, especially during the period of lower salinity. This same pattern was found for the endangered Spanish toothcarp (Aphanius iberus. Overall, introduced species were favoured by low salinity, which highlights the importance of changing the present water management by reducing the freshwater inputs in order to maintain suitable levels of salinity to favour native species that are important for both commercial and conservation purposes.

  3. Neonatal risk factors for cerebral palsy in very preterm babies: case-control study.

    Science.gov (United States)

    Murphy, D. J.; Hope, P. L.; Johnson, A.

    1997-01-01

    OBJECTIVE: To identify neonatal risk factors for cerebral palsy among very preterm babies and in particular the associations independent of the coexistence of antenatal and intrapartum factors. DESIGN: Case-control study. SETTING: Oxford health region. SUBJECTS: Singleton babies born between 1984 and 1990 at less than 32 weeks' gestation who survived to discharge from hospital: 59 with cerebral palsy and 234 randomly selected controls without cerebral palsy. MAIN OUTCOME MEASURES: Adverse neonatal factors expressed as odds ratios and 95% confidence intervals. RESULTS: Factors associated with an increased risk of cerebral palsy after adjustment for gestational age and the presence of previously identified antenatal and intrapartum risk factors were patent ductus arteriosus (odds ratio 2.3; 95% confidence interval 1.2 to 4.5), hypotension (2.3; 1.3 to 4.7), blood transfusion (4.8; 2.5 to 9.3), prolonged ventilation (4.8; 2.5 to 9.0), pneumothorax (3.5; 1.6 to 7.6), sepsis (3.6; 1.8 to 7.4), hyponatraemia (7.9; 2.1 to 29.6) and total parenteral nutrition (5.5; 2.8 to 10.5). Seizures were associated with an increased risk of cerebral palsy (10.0; 4.1 to 24.7), as were parenchymal damage (32; 12.4 to 84.4) and appreciable ventricular dilatation (5.4; 3.0 to 9.8) detected by cerebral ultrasound. CONCLUSION: A reduction in the rate of cerebral palsy in very preterm babies requires an integrated approach to management throughout the antenatal, intrapartum, and neonatal periods. PMID:9040385

  4. Duct corrosion in the ventilating air conditioning system for Main Control Room

    International Nuclear Information System (INIS)

    Yamada, Kohei; Kobayashi, Takashi; Minami, Akiko; Fukuba, Kazushi

    2014-01-01

    Higashidori Nuclear Power Station, start-of-operation in December 2005, is a relatively new plant. We decided to get original data of air duct condition to determine maintenance policy of air duct, because planned maintenance of air duct has never been done and the corrosion of air duct has occurred in other plant. In January 2014, we found a corrosion-hole at the downstream of the inlet damper in the ventilating air conditioning system for Main Control Room (MCR). We supposed that the cause of rapid corrosion is related to the characteristic environment of this site. (author)

  5. [Distribution and main influential factors of mental workload of middle school teachers in Nanchang City].

    Science.gov (United States)

    Xiao, Yuanmei; Li, Weijuan; Ren, Qingfeng; Ren, Xiaohui; Wang, Zhiming; Wang, Mianzhen; Lan, Yajia

    2015-01-01

    To investigate the distribution and main influential factors of mental workload of middle school teachers in Nanchang City. A total of 504 middle school teachers were sampled by random cluster sampling from middle schools in Nanchang City, and the mental workload level was assessed with National Aeronautics and Space Administration-Task Load Index (NASA-TLX) which was verified in reliability and validity. The mental workload scores of middle school teachers in Nanchang was approximately normal distribution. The mental workload level of middle school teachers aged 31 -35 years old was the highest. For those no more than 35 years old, there was positive correlation between mental workload and age (r = 0.146, P teachers with lower educational level seemed to have a higher mental workload (P teacher worked per day, the higher the mental workload was. Working hours per day was the most influential factor on mental workload in all influential factors (P teachers was closely related to age, educational level and work hours per day. Working hours per day was the important risk factor of mental workload. Reducing working hours per day, especially reducing it to be no more than 8 hours per day, may be a significant and useful approach alleviating mental workload of middle school teachers in Nanchang City.

  6. Environmental factors in the development of chronic inflammation: A case-control study on risk factors for Crohn's disease within New Zealand

    International Nuclear Information System (INIS)

    Han, Dug Yeo; Fraser, Alan G.; Dryland, Philippa; Ferguson, Lynnette R.

    2010-01-01

    The role of environmental factors in the risk for Crohn's disease (CD), an inflammatory bowel disease (IBD), was investigated in a North Island-based New Zealand case-control cohort. A total of 315 CD patients and 536 controls were recruited through various sources to the Auckland CD Risk Factor Study. As well as demographic characteristics, the self-reported questionnaire included (1) smoking and drinking alcohol, (2) breastfeeding in infancy, (3) early life exposures to allergens and microbes, (4) health conditions lasting 6 months or longer and (5) taking antibiotics and any medications. There was strong evidence for familial associations of the disease, and minor effects of birth order and number of siblings. Being a smoker, especially over a long time period, and exposure to smoking during childhood and adolescence periods increased risk, whereas drinking alcohol at least once per week showed a slight protective effect. Long term use of the oral contraceptive pill increased the risk of developing CD, but breastfeeding and immunisation during infancy showed no significant association. Long term and debilitating illness (lasting 6 months or more), taking antibiotics prior to developing CD, or taking four or more antibiotics or any regular medication in a year during adolescence substantially increased the CD risk. Having a pet during childhood was a protective factor, but regularly feeding an animal was not sufficient to protect. Many of these significant factors are likely to impact on the colonic microflora and/or immune system. We conclude that, in addition to strong evidence for genetic associations, factors likely to impact on immune response or reduce early exposure to microbes provide a main risk factor for CD in this New Zealand population.

  7. Robust extraction of basis functions for simultaneous and proportional myoelectric control via sparse non-negative matrix factorization

    Science.gov (United States)

    Lin, Chuang; Wang, Binghui; Jiang, Ning; Farina, Dario

    2018-04-01

    Objective. This paper proposes a novel simultaneous and proportional multiple degree of freedom (DOF) myoelectric control method for active prostheses. Approach. The approach is based on non-negative matrix factorization (NMF) of surface EMG signals with the inclusion of sparseness constraints. By applying a sparseness constraint to the control signal matrix, it is possible to extract the basis information from arbitrary movements (quasi-unsupervised approach) for multiple DOFs concurrently. Main Results. In online testing based on target hitting, able-bodied subjects reached a greater throughput (TP) when using sparse NMF (SNMF) than with classic NMF or with linear regression (LR). Accordingly, the completion time (CT) was shorter for SNMF than NMF or LR. The same observations were made in two patients with unilateral limb deficiencies. Significance. The addition of sparseness constraints to NMF allows for a quasi-unsupervised approach to myoelectric control with superior results with respect to previous methods for the simultaneous and proportional control of multi-DOF. The proposed factorization algorithm allows robust simultaneous and proportional control, is superior to previous supervised algorithms, and, because of minimal supervision, paves the way to online adaptation in myoelectric control.

  8. Control and reversal of biofilm episode in a nuclear power plant main condenser system

    International Nuclear Information System (INIS)

    Terry, J.P.; Schultz, G.; Ewens, S.

    1996-01-01

    This paper documents a biofilm episode in the main condenser of the Callaway Generating Station. The problem was reversed by the use of oxidizing biocide and a wetting/penetrating agent, along with pH adjustments and other measures. All of the factors leading up to the problem are discussed in detail as are the measures taken to reverse the problem. The most difficult aspect of the problem was identifying the onset of biofilm buildup. The existing background noise in the back pressure and fouling factor data obscured the early stages of the problem and delayed detection and treatment. Alternative monitoring techniques are discussed and the treatment and reversal of the problem are completely documented. The rationale for differentiating between biofouling and deposition caused by inorganic precipitation are discussed

  9. Economic and Social Factors in Designing Disease Control Strategies for Epidemics on Networks

    Science.gov (United States)

    Kleczkowski, A.; Dybiec, B.; Gilligan, C. A.

    2006-11-01

    Models for control of epidemics on local, global and small-world networks are considered, with only partial information accessible about the status of individuals and their connections. The main goal of an effective control measure is to stop the epidemic at a lowest possible cost, including treatment and cost necessary to track the disease spread. We show that delay in detection of infectious individuals and presence of long-range links are the most important factors determining the cost. However, the details of long-range links are usually the least-known element of the social interactions due to their occasional character and potentially short life-span. We show that under some conditions on the probability of disease spread, it is advisable to attempt to track those links, even if this involves additional costs. Thus, collecting some additional knowledge about the network structure might be beneficial to ensure a successful and cost-effective control.

  10. THE CONCEPT OF ENTERPRISE COMPETITIVENESS AND THE MAIN FACTORS FOR ITS PROVISION IN CONSTRUCTION INDUSTRY

    Directory of Open Access Journals (Sweden)

    Potapova Irina Ivanovna

    2018-01-01

    Full Text Available Competitiveness of construction enterprises is the most important characteristic of the enterprise activity, which every business entity must constantly evaluate and undertake various kinds of measures to increase it. The development and implementation of these activities should be carried out with a clear understanding of the content of the enterprise competitiveness, and also by forming and analyzing the list of factors that affect the competitiveness. Subject: competitiveness of construction industry enterprises. Research objectives: reflecting the content of the notion of enterprise competitiveness and the main factors of its provision in the construction industry. Materials and methods: in the process of research, we applied the principles of ascent from abstract to specific, the unity of logical analysis, systematization, structuring and generalization. In the process of writing the paper, we used research and educational literature, articles in periodicals, Internet sources. Results: it is proposed to adhere to an integrated approach, according to which the competitiveness of an enterprise should be understood as the ability of an enterprise to conduct activities in the market, outrunning competitors, effectively using its own internal capabilities and taking into account environmental factors, paying attention to market conditions, features of regional development, characteristics of the industry, and at the same time, making sufficient profit that allows the enterprise to increase its potential. It is important to note that the factors of ensuring the competitiveness of the enterprise are mostly divided into external and internal ones, which, of course, is suitable for construction companies because they are open systems influenced by factors of the external and internal environment. The conducted analysis of the external factors allowed us to divide them into four groups: world-class factors, macro-level factors, meso-level factors and

  11. The Relationship between Five Main Factors of Personality and Addiction to SMS in High School Students

    OpenAIRE

    Atefeh Beydokhti; Ramazan Hassanzadeh; Bahram Mirzaian

    2012-01-01

    Today, mobile phones compared with computers and Internet technology, have a greater impact on social life, people's lifestyle and their consumer behavior, because mobile phones are cheap and easy to use. This paper aims to examine the relationship between 5 main personality factors, neuroticism, extroversion and addiction of students to SMS. The statistical population consisted of all high school students studying in the academic year (2011-2012) which totally are 7520 people of which 364 st...

  12. Role Allocations and Communications of Operators during Emergency Operation in Advanced Main Control Rooms

    International Nuclear Information System (INIS)

    Lee, June Seung

    2009-01-01

    The advanced main control room (MCR) in GEN III + nuclear power plants has been designed by adapting modern digital I and C techniques and an advanced man machine interface system (MMIS). Large Display Panels (LDPs) and computer based workstations are installed in the MCR. A Computerized Procedure System (CPS) and Computerized Operation Support System (COSS) with high degrees of automation are supplied to operators. Therefore, it is necessary to set up new operation concepts in advanced MCRs that are different from those applied in conventional MCRs regarding role allocations and communications of operators. The following presents a discussion of the main differences between advanced MCRs and conventional MCRs from the viewpoint of role allocations and communications. Efficient models are then proposed on the basis of a task analysis on a series of emergency operation steps

  13. Experimental evidence of a dual endocrine control of biosynthesis in the main nidamental glands of Sepia officinalis L. by factors from the central nervous system and the ovary.

    Science.gov (United States)

    Henry, J; Boucaud-Camou, E

    1993-12-01

    1. A rapid, reliable and quantitative in vitro bioassay was developed to study the endocrine control of the biosynthesis of the egg capsule: incorporation of 14C-labelled D-glucose in polysaccharides and glycoproteins increased in dispersed-cell suspensions of main nidamental glands from maturing females. 2. Brain, optic lobes (OL) and ovary extracts from mature and maturing females stimulated the incorporation of 14C-labelled D-glucose in polysaccharidic and glycoproteic fractions of a nidamental cell suspension, whereas optic gland (OG) had no effect. 3. These results bring the first experimental evidence that one of the spawning events (egg-capsule edification) is controlled by the central nervous system and the ovary in a cephalopod.

  14. An Investigation for Arranging the Video Display Unit Information in a Main Control Room of Advanced Nuclear Power Plants

    Energy Technology Data Exchange (ETDEWEB)

    Hsu, Chong Cheng; Yang, Chih Wei [Institute of Nuclear Energy Research, Atomic Energy Council, Taoyuan (China)

    2014-08-15

    Current digital instrumentation and control and main control room (MCR) technology has extended the capability of integrating information from numerous plant systems and transmitting needed information to operations personnel in a timely manner that could not be envisioned when previous generation plants were designed and built. A MCR operator can complete all necessary operating actions on the video display unit (VDU). It is extremely flexible and convenient for operators to select and to control the system display on the screen. However, a high degree of digitalization has some risks. For example, in nuclear power plants, failures in the instrumentation and control devices could stop the operation of the plant. Human factors engineering (HFE) approaches would be a manner to solve this problem. Under HFE considerations, there exists 'population stereotype' for operation. That is, the operator is used to operating a specific display on the specific VDU for operation. Under emergency conditions, there is possibility that the operator will response with this habit population stereotype, and not be aware that the current situation has already changed. Accordingly, the advanced nuclear power plant should establish the MCR VDU configuration plan to meet the consistent teamwork goal under normal operation, transient and accident conditions. On the other hand, the advanced nuclear power plant should establish the human factors verification and validation plan of the MCR VDU configuration to verify and validate the configuration of the MCR VDUs, and to ensure that the MCR VDU configuration allows the operator shift to meet the HFE consideration and the consistent teamwork goal under normal operation, transient and accident conditions. This paper is one of the HF V V plans of the MCR VDU configuration of the advanced nuclear power plant. The purpose of this study is to confirm whether the VDU configuration meets the human factors principles and the consistent

  15. An Investigation for Arranging the Video Display Unit Information in a Main Control Room of Advanced Nuclear Power Plants

    International Nuclear Information System (INIS)

    Hsu, Chong Cheng; Yang, Chih Wei

    2014-01-01

    Current digital instrumentation and control and main control room (MCR) technology has extended the capability of integrating information from numerous plant systems and transmitting needed information to operations personnel in a timely manner that could not be envisioned when previous generation plants were designed and built. A MCR operator can complete all necessary operating actions on the video display unit (VDU). It is extremely flexible and convenient for operators to select and to control the system display on the screen. However, a high degree of digitalization has some risks. For example, in nuclear power plants, failures in the instrumentation and control devices could stop the operation of the plant. Human factors engineering (HFE) approaches would be a manner to solve this problem. Under HFE considerations, there exists 'population stereotype' for operation. That is, the operator is used to operating a specific display on the specific VDU for operation. Under emergency conditions, there is possibility that the operator will response with this habit population stereotype, and not be aware that the current situation has already changed. Accordingly, the advanced nuclear power plant should establish the MCR VDU configuration plan to meet the consistent teamwork goal under normal operation, transient and accident conditions. On the other hand, the advanced nuclear power plant should establish the human factors verification and validation plan of the MCR VDU configuration to verify and validate the configuration of the MCR VDUs, and to ensure that the MCR VDU configuration allows the operator shift to meet the HFE consideration and the consistent teamwork goal under normal operation, transient and accident conditions. This paper is one of the HF V V plans of the MCR VDU configuration of the advanced nuclear power plant. The purpose of this study is to confirm whether the VDU configuration meets the human factors principles and the consistent

  16. The factors controlling species density in herbaceous plant communities: An assessment

    Science.gov (United States)

    Grace, J.B.

    1999-01-01

    This paper evaluates both the ideas and empirical evidence pertaining to the control of species density in herbaceous plant communities. While most theoretical discussions of species density have emphasized the importance of habitat productivity and disturbance regimes, many other factors (e.g. species pools, plant litter accumulation, plant morphology) have been proposed to be important. A review of literature presenting observations on the density of species in small plots (in the vicinity of a few square meters or less), as well as experimental studies, suggests several generalizations: (1) Available data are consistent with an underlying unimodal relationship between species density and total community biomass. While variance in species density is often poorly explained by predictor variables, there is strong evidence that high levels of community biomass are antagonistic to high species density. (2) Community biomass is just one of several factors affecting variations in species density. Multivariate analyses typically explain more than twice as much variance in species density as can be explained by community biomass alone. (3) Disturbance has important and sometimes complex effects on species density. In general, the evidence is consistent with the intermediate disturbance hypothesis but exceptions exist and effects can be complex. (4) Gradients in the species pool can have important influences on patterns of species density. Evidence is mounting that a considerable amount of the observed variability in species density within a landscape or region may result from environmental effects on the species pool. (5) Several additional factors deserve greater consideration, including time lags, species composition, plant morphology, plant density and soil microbial effects. Based on the available evidence, a conceptual model of the primary factors controlling species density is presented here. This model suggests that species density is controlled by the effects of

  17. Risk factors for gallbladder cancer: a case-control study.

    Science.gov (United States)

    Jain, Kajal; Sreenivas, V; Velpandian, T; Kapil, Umesh; Garg, Pramod Kumar

    2013-04-01

    Risk factors for gallbladder cancer (GBC) except gallstones are not well known. The objective was to study the risk factors for GBC. In a case-control study, 200 patients with GBC, 200 healthy controls and 200 gallstones patients as diseased controls were included prospectively. The risk factors studied were related to socioeconomic profile, life style, reproduction, diet and bile acids. On comparing GBC patients (mean age 51.7 years; 130 females) with healthy controls, risk factors were chemical exposure [odd ratios (OR): 7.0 (2.7-18.2); p < 0.001)], family history of gallstones [OR: 5.3 (1.5-18.9); p < 0.01)], tobacco [OR: 4.1 (1.8-9.7); p < 0.001)], fried foods [OR: 3.1 (1.7-5.6); p < 0.001], joint family [OR: 3.2 (1.7-6.2); p < 0.001], long interval between meals [OR: 1.4 (1.2-1.6); p < 0.001] and residence in Gangetic belt [OR: 3.3 (1.8-6.2); p < 0.001]. On comparing GBC cases with gallstone controls, risk factors were female gender [OR: 2.4 (1.3-4.3); p = 0.004], residence in Gangetic belt [OR: 2.3 (1.2-4.4); p = 0.012], fried foods [OR: 2.5 (1.4-4.4); p < 0.001], diabetes [OR: 2.7 (1.2-6.4); p = 0.02)], tobacco [OR 3.8 (1.7-8.1); p < 0.001)] and joint family [OR: 2.1 (1.2-3.4); p = 0.004]. The ratio of secondary to primary bile acids was significantly higher in GBC cases than gallstone controls (20.8 vs. 0.44). Fried foods, tobacco, chemical exposure, family history of gallstones, residence in Gangetic belt and secondary bile acids were significant risk factors for GBC. Copyright © 2012 UICC.

  18. WHEN STRESS AND DEVELOPMENT GO HAND IN HAND: MAIN HORMONAL CONTROLS OF ADVENTITIOUS ROOTING IN CUTTINGS

    Directory of Open Access Journals (Sweden)

    Cibele Tesser Da Costa

    2013-05-01

    Full Text Available Adventitious rooting (AR is a multifactorial response leading to new roots at the base of stem cuttings, and the establishment of a complete and autonomous plant. AR has two main phases: a induction, with a requirement for higher auxin concentration; b formation, inhibited by high auxin and in which anatomical changes take place. The first stages of this process in severed organs necessarily include wounding and water stress responses which may trigger hormonal changes that contribute to reprogram target cells that are competent to respond to rooting stimuli. At severance, the roles of jasmonate and abscisic acid are critical for wound response and perhaps sink strength establishment, although their negative roles on the cell cycle may inhibit root induction. Strigolactones may also inhibit AR. A reduced cytokinin concentration in cuttings results from the separation of the root system, whose tips are a relevant source of these root induction inhibitors. The combined increased accumulation of basipetally transported auxins from the shoot apex at the cutting base is often sufficient for AR in easy-to-root species. The role of peroxidases and phenolic compounds in auxin catabolism may be critical at these early stages right after wounding. The events leading to AR strongly depend on mother plant nutritional status, both in terms of minerals and carbohydrates, as well as on sink establishment at cutting bases. Auxins play a central role in AR. Auxin transporters control auxin canalization to target cells. There, auxins act primarily through selective proteolysis and cell wall loosening, via their receptor proteins TIR1 and ABP1. A complex microRNA circuitry is involved in the control of auxin response factors essential for gene expression in AR. After root establishment, new hormonal controls take place, with auxins being required at lower concentrations for root meristem maintenance and cytokinins needed for root tissue differentiation.

  19. Autoconceito dos professores: principais factores usando modelos de Análise de Dados Multivariada Teachers' self-concept: finding main factors and clusters by EDA models

    Directory of Open Access Journals (Sweden)

    Vitor Franco

    2008-01-01

    Full Text Available O autoconceito tem sido considerado uma dimensão muito importante da personalidade do professor, da sua prática e do seu desenvolvimento pessoal (MARKUS; WURF, 1987; SIMÕES, 2001. A investigação que apresentamos foi efectuada com 281 professores de Ciências da Natureza, do terceiro ciclo do Ensino Básico, em Portugal, usando o ICAC- Inventário Clínico do Auto Conceito (VAZ-SERRA, 1986. Na análise dos dados obtidos foram usados diferentes métodos de Análise Multivariada, apresentando-se os resultados da análise factorial de correspondências e nos modelos de classificação hierárquica baseados no coeficiente de afinidade. Os resultados obtidos: 1 confirmam a importância de dois grandes factores presentes no Autoconceito: aceitação social e auto-eficácia; 2 caracterizam estes principais factores no que se refere ao Autoconceito clínico dos professores; 3 mostram como esses factores são determinantes na forma como cada professor constroi o seu autoconceito.The self-concept has been considered as a very important dimension on teacher's personality, practice and development (MARKUS; WURF, 1987;SIMÕES, 2001. The present research concerns a sample of 281 teachers of Natural Science of the Third Cycle of Basic Education from Portugal that responded to the I.C.A.C. - Self-Concept Clinical Inventory (VAZ-SERRA, 1986. In the analysis of the questionnaires different multivariate data analysis methods have been used. This paper describes some results issued from correspondence analysis and hierarchical clustering models based on the affinity coefficient. The results obtained: 1 confirm the importance of two general main factors / types which are present in self-concept: social acceptance and self-efficiency; 2 characterise these main factors when teachers'clinical self-concept is concerned and 3 show how determinant these factors are for the building of self-concept that allow us to differentiate teachers.

  20. European multi-centre case-control study on risk factors for rare cancers of unknown aetiology

    DEFF Research Database (Denmark)

    Lynge, Elsebeth; Afonso, Noemia; Kaerlev, Linda

    2005-01-01

    To search for occupational risk factors, we conducted a case-control study in nine European countries of cancers of the small intestine, male gall bladder, thymus, bone, male breast, melanoma of the eye, and mycosis fungoides. Recruitment was population based in Denmark, Latvia, France, Germany...... recruited 3374 population (61% interviewed) and 1284 colon cancer controls (86% interviewed). It was possible to undertake this complicated study across Europe, but we encountered three main problems. It was difficult to ensure complete case ascertainment, for population controls, we found a clear divide......, Italy, and Sweden, from hospital areas in Spain and Portugal, and from one United Kingdom (UK) hospital. We recruited 1457 cases (84% interviewed). Numbers identified corresponded to those in the EUROCIM database for Denmark, but were below those observed for France, Italy and Sweden in the database. We...

  1. A HUMAN FACTORS ENGINEERING PROCESS TO SUPPORT HUMAN-SYSTEM INTERFACE DESIGN IN CONTROL ROOM MODERNIZATION

    Energy Technology Data Exchange (ETDEWEB)

    Kovesdi, C.; Joe, J.; Boring, R.

    2017-05-01

    The primary objective of the United States (U.S.) Department of Energy (DOE) Light Water Reactor Sustainability (LWRS) program is to sustain operation of the existing commercial nuclear power plants (NPPs) through a multi-pathway approach in conducting research and development (R&D). The Advanced Instrumentation, Information, and Control (II&C) System Technologies pathway conducts targeted R&D to address aging and reliability concerns with legacy instrumentation and control (I&C) and other information systems in existing U.S. NPPs. Control room modernization is an important part following this pathway, and human factors experts at Idaho National Laboratory (INL) have been involved in conducting R&D to support migration of new digital main control room (MCR) technologies from legacy analog and legacy digital I&C. This paper describes a human factors engineering (HFE) process that supports human-system interface (HSI) design in MCR modernization activities, particularly with migration of old digital to new digital I&C. The process described in this work is an expansion from the LWRS Report INL/EXT-16-38576, and is a requirements-driven approach that aligns with NUREG-0711 requirements. The work described builds upon the existing literature by adding more detail around key tasks and decisions to make when transitioning from HSI Design into Verification and Validation (V&V). The overall objective of this process is to inform HSI design and elicit specific, measurable, and achievable human factors criteria for new digital technologies. Upon following this process, utilities should have greater confidence with transitioning from HSI design into V&V.

  2. IAEA technical meeting on integrating analog and digital instrumentation and control systems in hybrid main control rooms at nuclear power plants. Book of abstracts

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2007-07-01

    that digital technology offers are needed to increase cost-effective electricity production. As an integral part of the I and C modernization program at a nuclear power plant, the control room and other human-system interfaces (HSIs) will also be modernized. To support safe and effective operation, it is critical to specify, design, implement, operate, and maintain, as well as train for, the control room and HSI changes to take advantage of human cognitive processing abilities. This consideration of human factors is essential to increase performance and to reduce the likelihood of human errors. The plant I and C and HSI modifications can affect personnel in various ways. They can impact the role of personnel, the tasks to be performed, the way tasks are performed, and the knowledge, skills and training required of personnel. As part of modernization, HSIs are becoming more computer-based, incorporating features such as soft controls and computerized procedures, touch-screen interfaces, sit-down workstations, and large-screen overview displays. As computer-based technologies are integrated into control rooms that were largely based on conventional technology, hybrid control rooms are created. The potential benefits of implementing digital technology include more efficient operations and maintenance, leading to improved power plant availability and safety through the avoidance of transients, forced outages, and unnecessary shutdowns. The potential benefits also include increased efficiency and power output as well as reduced operating costs. New digital systems provide the opportunity to give personnel information they did not have with conventional systems. The importance of these issues has led the IAEA to organize (in conjunction with AECL) an international forum for presentations and discussions on the potential benefits and challenges related to the integration of Analog and Digital Instrumentation and Control Systems in Hybrid Main Control Rooms. Many of these

  3. Main Control Room Upgrade for Kori Unit 1 in Korea

    International Nuclear Information System (INIS)

    Ha, Jae Taeg; Choi, Moon Jae

    2014-01-01

    Kori Unit 1 is a 30 years old nuclear power plant and its MCR and MCB was upgraded based on the latest Human Factors Engineering (HFE) principles. The objectives of applying the Human Factors Engineering (HFE) principles are to minimize the human errors and to enhance the safe operation of the plant. In order to systematically incorporate the HFE design principles into the Human System Interface (HSI) design, HFE Program Plan (HFEPP) for Kori Unit 1 was developed and the plan provided an overview of the HSI design process along with detailed methods and results. The upgrade includes addition of Bypassed and Inoperable Status Indication System (BISI) and the replacement of the conventional MMI devices such as hardwired hand switches, recorders and indicators with new advanced control and display devices using VDUs (Video Display Units). The VDUs significantly improve the effectiveness and efficiency of the monitoring function. Plant Monitoring System (PMS) and Plant Annunciator System (PAS) were upgraded also by replacing the outdated systems with advanced digital systems with future expansion capability. In addition, the MCR related equipment and/or facilities were replaced or improved. Some of these include the enhancement of MCR interior designs for better working environment, dimmable ceiling lighting, aesthetically pleasing decor of ceiling, wall and floor as well as ergonomically improved operator consoles

  4. Main Control Room Upgrade for Kori Unit 1 in Korea

    Energy Technology Data Exchange (ETDEWEB)

    Ha, Jae Taeg; Choi, Moon Jae [KEPCO, Daejeon (Korea, Republic of)

    2014-08-15

    Kori Unit 1 is a 30 years old nuclear power plant and its MCR and MCB was upgraded based on the latest Human Factors Engineering (HFE) principles. The objectives of applying the Human Factors Engineering (HFE) principles are to minimize the human errors and to enhance the safe operation of the plant. In order to systematically incorporate the HFE design principles into the Human System Interface (HSI) design, HFE Program Plan (HFEPP) for Kori Unit 1 was developed and the plan provided an overview of the HSI design process along with detailed methods and results. The upgrade includes addition of Bypassed and Inoperable Status Indication System (BISI) and the replacement of the conventional MMI devices such as hardwired hand switches, recorders and indicators with new advanced control and display devices using VDUs (Video Display Units). The VDUs significantly improve the effectiveness and efficiency of the monitoring function. Plant Monitoring System (PMS) and Plant Annunciator System (PAS) were upgraded also by replacing the outdated systems with advanced digital systems with future expansion capability. In addition, the MCR related equipment and/or facilities were replaced or improved. Some of these include the enhancement of MCR interior designs for better working environment, dimmable ceiling lighting, aesthetically pleasing decor of ceiling, wall and floor as well as ergonomically improved operator consoles.

  5. The modern instrumentation used for monitoring and controlling the main parameters of the regenerative electro-mechano-hydraulic drive systems

    Science.gov (United States)

    Cristescu, Corneliu; Drumea, Petrin; Krevey, Petrica

    2009-01-01

    In this work is presented the modern instrumentation used for monitoring and controlling the main parameters for one regenerative drive system, used to recovering the kinetic energy of motor vehicles, lost in the braking phase, storing and using this energy in the starting or accelerating phases. Is presented a Romanian technical solution for a regenerative driving system, based on a hybrid solution containing a hydro-mechanic module and an existing thermal motor drive, all conceived as a mechatronics system. In order to monitoring and controlling the evolution of the main parameters, the system contains a series of sensors and transducers that provide the moment, rotation, temperature, flow and pressure values. The main sensors and transducers of the regenerative drive system, their principal features and tehnical conecting solutions are presented in this paper, both with the menaging electronic and informational subsystems.

  6. Environmental factors in the development of chronic inflammation: A case-control study on risk factors for Crohn's disease within New Zealand

    Energy Technology Data Exchange (ETDEWEB)

    Han, Dug Yeo [Discipline of Nutrition, Faculty of Medical and Health Sciences, University of Auckland, Private Bag 92019, Auckland (New Zealand); Fraser, Alan G. [Department of Medicine, Faculty of Medical and Health Sciences, University of Auckland, Private Bag 92019, Auckland (New Zealand); Dryland, Philippa [Discipline of Nutrition, Faculty of Medical and Health Sciences, University of Auckland, Private Bag 92019, Auckland (New Zealand); Ferguson, Lynnette R., E-mail: l.ferguson@auckland.ac.nz [Discipline of Nutrition, Faculty of Medical and Health Sciences, University of Auckland, Private Bag 92019, Auckland (New Zealand)

    2010-08-07

    The role of environmental factors in the risk for Crohn's disease (CD), an inflammatory bowel disease (IBD), was investigated in a North Island-based New Zealand case-control cohort. A total of 315 CD patients and 536 controls were recruited through various sources to the Auckland CD Risk Factor Study. As well as demographic characteristics, the self-reported questionnaire included (1) smoking and drinking alcohol, (2) breastfeeding in infancy, (3) early life exposures to allergens and microbes, (4) health conditions lasting 6 months or longer and (5) taking antibiotics and any medications. There was strong evidence for familial associations of the disease, and minor effects of birth order and number of siblings. Being a smoker, especially over a long time period, and exposure to smoking during childhood and adolescence periods increased risk, whereas drinking alcohol at least once per week showed a slight protective effect. Long term use of the oral contraceptive pill increased the risk of developing CD, but breastfeeding and immunisation during infancy showed no significant association. Long term and debilitating illness (lasting 6 months or more), taking antibiotics prior to developing CD, or taking four or more antibiotics or any regular medication in a year during adolescence substantially increased the CD risk. Having a pet during childhood was a protective factor, but regularly feeding an animal was not sufficient to protect. Many of these significant factors are likely to impact on the colonic microflora and/or immune system. We conclude that, in addition to strong evidence for genetic associations, factors likely to impact on immune response or reduce early exposure to microbes provide a main risk factor for CD in this New Zealand population.

  7. Assessing dietary and lifestyle risk factors and their associations with disease comorbidities among patients with schizophrenia: A case-control study from Bahrain.

    Science.gov (United States)

    Jahrami, Haitham Ali; Faris, Mo'ez Al-Islam Ezzat; Saif, Zahraa Qassim; Hammad, Laila Habib

    2017-08-01

    Acquired dietary habits and lifestyle behaviors of patients with schizophrenia may affect their life expectancy, disease complications and prognosis. The objectives of the current study were to assess the dietary habits and other lifestyle behaviors for Bahraini patients with schizophrenia, and to determine their associations with different medical comorbidities. A case-control study was conducted during the period of March to December 2016. A sample of 120 cases were recruited from the Psychiatric Hospital, Bahrain and age-sex-matched with 120 controls. Controls were recruited from primary health centres, and were free from serious mental illness. Dietary habits and lifestyle behaviors including smoking, alcohol intake and physical activity were assessed using a questionnaire. All medical records were reviewed retrospectively. Logistic regression analysis was used to identify dietary and lifestyle risk factors that are associated with one or more disease comorbidities. Cases had higher prevalence of smoking and alcohol intake, excessive dietary intake, and decreased physical activity (all Prisk for developing chronic medical conditions such as obesity, type 2 diabetes, hypertension, cardiovascular disease, and musculoskeletal disorders. Cases were three times more likely to have up to three or more medical comorbidities compared with controls. Excessive dietary intake and decreased physical activity were identified as the main risk factors. Excessive caloric intake and decreased physical activity represent the main dietary and lifestyle risk factors associated with comorbidities among patients with schizophrenia in Bahrain. Copyright © 2017 Elsevier B.V. All rights reserved.

  8. Factores de riesgo para carcinoma basocelular: Estudio de casos-controles en Córdoba Risk factors for basal cell carcinoma: Case-control study in Cordoba

    Directory of Open Access Journals (Sweden)

    Alejandro Ruiz Lascano

    2005-12-01

    Full Text Available El carcinoma basocelular es una enfermedad compleja. Su etiología es todavía poco clara y a pesar de su frecuencia hay pocos datos sobre factores de riesgo. Nosotros evaluamos factores de riesgo potenciales para carcinoma basocelular en una población de Córdoba (Argentina. Este estudio de casos y controles incluyó a 88 casos nuevos de carcinoma basocelular, y 88 controles pareados por sexo y edad. Los siguientes factores de riesgo fueron significativos en el análisis multivariado: fototipos I, II y III, exposición solar recreativa alta después de los 20 años de edad, exposición solar alta en vacaciones en la playa y la presencia de queratosis actínicas.Basal cell carcinoma is undoubtedly a complex disease. Its etiology is still unclear and despite its frequency, there is a paucity of data on its risk factors. We assessed potential risk factors for basal cell carcinoma in a population from Córdoba (Argentina. This case-control study involved 88 newly diagnosed cases and 88 controls, matched by age and sex. The following risk factors were significant in the multivariate analysis: skin type I-II-III, high recreational sun exposure after 20 years of age, high sun exposure for beach holidays and actinic keratosis.

  9. A proactive alarm reduction method and its human factors validation test for a main control room for SMART

    International Nuclear Information System (INIS)

    Jang, Gwi-sook; Suh, Sang-moon; Kim, Sa-kil; Suh, Yong-suk; Park, Je-yun

    2013-01-01

    Highlights: ► A proactive alarm reduction method improves effectiveness on the alarm reduction. ► The method suppresses alarms based on the ECA rules and facts for the alarm reduction under an alarm flood situation. ► The alarm reduction logics are supplemented to a high hit ratio of the reduction logics during on-line operations. ► The method is validated by human factors validation test based on regulatory requirements. -- Abstract: Conventional alarm systems tend to overwhelm operators during a transient because of a large number of nearly simultaneous annunciator activations with varying degrees of relevance to operator tasks. Thus alarm processing techniques have developed to support operators in coping with the volume of alarms, to identify which alarms are significant, and to reduce the need for operators to infer the plant conditions. This paper proposes a proactive alarm reduction method for SMART (System-integrated Modular Advanced ReacTor) whereby based on the contents of the past operating effects alarm reduction is carried out during the next transient. We designed and implemented the proactive alarm reduction system and constructed the environment for the human factors validation test. Also, eight subjects actually working in a nuclear power plant (NPP) tested the practical effectiveness of the proposed proactive alarm reduction method according to the procedure of human factors validation test under a dynamic simulation of a partial scope for an NPP.

  10. Development of Alarm System link Drawing for Operation Support for APR1400 Digital Main Control Room

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Ki-Hwan [KHNP CRI, Daejeon (Korea, Republic of)

    2016-10-15

    Digitalized MMI(Man-Machine Interface) including Digital Main Control Room(MCR) and digital I and C system was being applied for SKN 3 and 4 Nuclear Power Plant(NPP) and subsequent APR1400 NPP type. But, operators can not easily find instrument for alarm immediately. Therefore, Alarm system is required to easily find instrument for Alarm. For this implementation, we will plan system design considering design feature without affecting network load and CPU load. We have developed Alarm system link drawing for digital MCR. Operators of the digitalized MCR navigates from their consoles to the drawings related to the plant alarms and their instruments or the operation status. Such method gives cognitive load to the operators having to travel to different locations in finding the related information. Screen Sharing System, which is the fundamental technique for Drawing Interconnection Alarm System is close to completion, and it should be functionally tested and verified by the human factor engineering. For the actual application to the operating plants, the drawings to be interconnected to the alarms and the opinions from the operators/maintenance departments for designating alarm number should be surveyed, Also, another function that allows the access to the alarm related drawings not only from the MCR but also from the other offices.

  11. Development of Alarm System link Drawing for Operation Support for APR1400 Digital Main Control Room

    International Nuclear Information System (INIS)

    Kim, Ki-Hwan

    2016-01-01

    Digitalized MMI(Man-Machine Interface) including Digital Main Control Room(MCR) and digital I and C system was being applied for SKN 3 and 4 Nuclear Power Plant(NPP) and subsequent APR1400 NPP type. But, operators can not easily find instrument for alarm immediately. Therefore, Alarm system is required to easily find instrument for Alarm. For this implementation, we will plan system design considering design feature without affecting network load and CPU load. We have developed Alarm system link drawing for digital MCR. Operators of the digitalized MCR navigates from their consoles to the drawings related to the plant alarms and their instruments or the operation status. Such method gives cognitive load to the operators having to travel to different locations in finding the related information. Screen Sharing System, which is the fundamental technique for Drawing Interconnection Alarm System is close to completion, and it should be functionally tested and verified by the human factor engineering. For the actual application to the operating plants, the drawings to be interconnected to the alarms and the opinions from the operators/maintenance departments for designating alarm number should be surveyed, Also, another function that allows the access to the alarm related drawings not only from the MCR but also from the other offices

  12. A review on the gun barrel vibrations and control for a main battle tank

    Directory of Open Access Journals (Sweden)

    Tolga Dursun

    2017-10-01

    Full Text Available Achieving high hitting accuracy for a main battle tank is challenging while the tank is on the move. This can be reached by proper design of a weapon control and gun system. In order to design an effective gun system while the tank is moving, better understanding of the dynamic behavior of the gun system is required. In this study, the dynamic behaviour of a gun system is discussed in this respect. Both experimental and numerical applications for the determination of the dynamic behaviour of a tank gun system are investigated. Methods such as the use of muzzle reference system (MRS and vibration absorbers, and active vibration control technology for the control and the reduction of the muzzle tip deflections are also reviewed. For the existing gun systems without making substantial modifications, MRS could be useful in controlling the deflections of gun barrels with estimation/prediction algorithms. The vibration levels could be cut into half by the use of optimised vibration absorbers for an existing gun. A new gun system with a longer barrel can be as accurate as the one with a short barrel with the appropriate structural modifications.

  13. Risk Factors for Progression or Malignancy in Main-Duct and Mixed-Type Intraductal Papillary Mucinous Neoplasm of the Pancreas.

    Science.gov (United States)

    Jang, Dong Kee; Ryu, Ji Kon; Chung, Kwang Hyun; Lee, Ban Seok; Park, Joo Kyung; Lee, Sang Hyub; Kim, Yong-Tae

    2016-08-01

    The 2012 international guidelines state that surgery should be considered for all surgically fit patients with pancreatic main-duct (MD)/mixed intraductal papillary mucinous neoplasms (IPMNs). This study evaluated the follow-up results of MD/mixed IPMNs and risk factors for progression or malignancy. Patients with MD/mixed IPMNs were retrospectively enrolled and divided into surgical and nonsurgical groups. These 2 groups were compared and further categorized as progression/malignancy or not. In the nonsurgical group, disease progression was defined as radiologic tumor growth or adjacent organ invasion. Data from 101 patients (73 males; mean [SD] age, 66.3 [9.1] years), including 27 and 74 in the nonsurgical and surgical groups, respectively, were analyzed. Mural nodules were more frequently detected in the surgical group (7.4% vs 31.1%, P = 0.018), whereas more multifocal cysts were observed in the nonsurgical group (40.7% vs 20.3%, P = 0.037). Forty-one patients (40.6%) showed progression or malignancy. Multivariate analysis showed that main pancreatic duct of 10 mm or greater (odds ratio, 4.368; P = 0.024) and pre-existing diabetes (odds ratio, 3.077; P = 0.046) were independent risk factors for progression or malignancy. A watchful waiting strategy could be feasible for some patients with MD/mixed IPMNs, particularly those with a main pancreatic duct of less than 10 mm and without diabetes.

  14. Risk factors for cataract: A case control study

    Directory of Open Access Journals (Sweden)

    Ughade Suresh

    1998-01-01

    Full Text Available The present study was designed as a hospital-based, group-matched, case-control investigation into the risk factors associated with age-related cataract in central India. The study included 262 cases of age-related cataract and an equal number of controls. A total of 21 risk factors were evaluated: namely, low socioeconomic status (SES, illiteracy, marital status, history of diarrhoea, history of diabetes, glaucoma, use of cholinesterase inhibitors, steroids, spironolactone, nifedipine, analgesics, myopia early in life, renal failure, heavy smoking, heavy alcohol consumption, hypertension, low body mass index (BMI, use of cheaper cooking fuel, working in direct sunlight, family history of cataract, and occupational exposure. In univariate analysis, except marital status, low BMI, renal failure, use of steroids, spironolactone, analgesics, and occupational exposure, all 14 other risk factors were found significantly associated with age-related cataract. Unconditional multiple logistic regression analysis confirmed the significance of low SES, illiteracy, history of diarrhoea, diabetes, glaucoma, myopia, smoking, hypertension and cheap cooking fuel. The etiological role of these risk factors in the outcome of cataract is confirmed by the estimates of attributable risk proportion. The estimates of population attributable risk proportion for these factors highlight the impact of elimination of these risk factors on the reduction of cataract in this population.

  15. Labeling programs and efficiency standards to control the energy consumption of household appliances: current situation, main results and recommendations

    Energy Technology Data Exchange (ETDEWEB)

    Menanteau, Ph.

    2000-09-01

    To control the rise in electricity consumption for specific uses, the industrialized countries started by introducing special programs aimed at improving energy efficiency. Among the different instruments available, labeling programs and minimum energy performance standards (MEPS) have proved to be very effective. The first part of this document presents the current situation, the main results and recommendations concerning the labeling programs and efficiency standards to control the energy consumption of household appliances. This analyze is done for each country in details providing the name of the program or measure, the date of implementation, the objective and the main characteristics of the program, the impacts and evaluation. (A.L.B.)

  16. Revisiting factors controlling methane emissions from high-Arctic tundra

    DEFF Research Database (Denmark)

    Mastepanov, M.; Sigsgaard, C.; Tagesson, T.

    2013-01-01

    controlling methane emission, i.e. temperature and water table position. Late in the growing season CH4 emissions were found to be very similar between the study years (except the extremely dry 2010) despite large differences in climatic factors (temperature and water table). Late-season bursts of CH4...... short-term control factors (temperature and water table). Our findings suggest the importance of multiyear studies with a continued focus on shoulder seasons in Arctic ecosystems....

  17. Power factor improvement in three-phase networks with unbalanced inductive loads using the Roederstein ESTAmat RPR power factor controller

    Science.gov (United States)

    Diniş, C. M.; Cunţan, C. D.; Rob, R. O. S.; Popa, G. N.

    2018-01-01

    The paper presents the analysis of a power factor with capacitors banks, without series coils, used for improving power factor for a three-phase and single-phase inductive loads. In the experimental measurements, to improve the power factor, the Roederstein ESTAmat RPR power factor controller can command up to twelve capacitors banks, while experimenting using only six capacitors banks. Six delta capacitors banks with approximately equal reactive powers were used for experimentation. The experimental measurements were carried out with a three-phase power quality analyser which worked in three cases: a case without a controller with all capacitors banks permanently parallel connected with network, and two other cases with power factor controller (one with setting power factor at 0.92 and the other one at 1). When performing experiments with the power factor controller, a current transformer was used to measure the current on one phase (at a more charged or less loaded phase).

  18. Performance related factors are the main determinants of the von Willebrand factor response to exhaustive physical exercise.

    Science.gov (United States)

    van Loon, Janine E; Sonneveld, Michelle A H; Praet, Stephan F E; de Maat, Moniek P M; Leebeek, Frank W G

    2014-01-01

    Physical stress triggers the endothelium to release von Willebrand Factor (VWF) from the Weibel Palade bodies. Since VWF is a risk factor for arterial thrombosis, it is of great interest to discover determinants of VWF response to physical stress. We aimed to determine the main mediators of the VWF increase by exhaustive physical exercise. 105 healthy individuals (18-35 years) were included in this study. Each participant performed an incremental exhaustive exercise test on a cycle ergometer. Respiratory gas exchange measurements were obtained while cardiac function was continuously monitored. Blood was collected at baseline and directly after exhaustion. VWF antigen (VWF:Ag) levels, VWF collagen binding (VWF:CB) levels, ADAMTS13 activity and common variations in Syntaxin Binding Protein-5 (STXBP5, rs1039084 and rs9399599), Syntaxin-2 (STX2, rs7978987) and VWF (promoter, rs7965413) were determined. The median VWF:Ag level at baseline was 0.94 IU/mL [IQR 0.8-1.1] and increased with 47% [IQR 25-73] after exhaustive exercise to a median maximum VWF:Ag of 1.38 IU/mL [IQR 1.1-1.8] (pexercise (median increase 43% and 12%, both pexercise (females 1.2 IU/mL; males 1.7 IU/mL, p = 0.001), which was associated by a difference in performance. Genetic variations in STXBP5, STX2 and the VWF promoter were not associated with VWF:Ag levels at baseline nor with the VWF:Ag increase. VWF:Ag levels strongly increase upon exhaustive exercise and this increase is strongly determined by physical fitness level and the intensity of the exercise, while there is no clear effect of genetic variation in STXBP5, STX2 and the VWF promoter.

  19. Evaluation of factors affecting adherence to asthma controller ...

    African Journals Online (AJOL)

    Evaluation of factors affecting adherence to asthma controller therapy in chest clinics in a sub-Saharan African setting: a cross-sectional study. ... Background: Adherence to controller therapy in asthma is a major concern during the management of the disease. Objective: To determine the adherence rate and identify the ...

  20. Experience with multiple control groups in a large population-based case-control study on genetic and environmental risk factors.

    Science.gov (United States)

    Pomp, E R; Van Stralen, K J; Le Cessie, S; Vandenbroucke, J P; Rosendaal, F R; Doggen, C J M

    2010-07-01

    We discuss the analytic and practical considerations in a large case-control study that had two control groups; the first control group consisting of partners of patients and the second obtained by random digit dialling (RDD). As an example of the evaluation of a general lifestyle factor, we present body mass index (BMI). Both control groups had lower BMIs than the patients. The distribution in the partner controls was closer to that of the patients, likely due to similar lifestyles. A statistical approach was used to pool the results of both analyses, wherein partners were analyzed with a matched analysis, while RDDs were analyzed without matching. Even with a matched analysis, the odds ratio with partner controls remained closer to unity than with RDD controls, which is probably due to unmeasured confounders in the comparison with the random controls as well as intermediary factors. However, when studying injuries as a risk factor, the odds ratio remained higher with partner control subjects than with RRD control subjects, even after taking the matching into account. Finally we used factor V Leiden as an example of a genetic risk factor. The frequencies of factor V Leiden were identical in both control groups, indicating that for the analyses of this genetic risk factor the two control groups could be combined in a single unmatched analysis. In conclusion, the effect measures with the two control groups were in the same direction, and of the same order of magnitude. Moreover, it was not always the same control group that produced the higher or lower estimates, and a matched analysis did not remedy the differences. Our experience with the intricacies of dealing with two control groups may be useful to others when thinking about an optimal research design or the best statistical approach.

  1. Main influence factors on the final energy generation cost of a nuclear power plant in comparison with other energy sources

    International Nuclear Information System (INIS)

    Souza, J.A.M. de; Glardon, C.; Schmidt, R.M.

    1981-01-01

    The main factors in the construction and in the operation of nuclear power plants that affect the final energy generation cost are presented. The structure of the energy generation cost, of the nuclear fuel cost and the total investment are studied. (E.G.) [pt

  2. Chest cage angle difference and rotation of main thoracic curve are independent risk factors of postoperative shoulder imbalance in surgically treated patients with adolescent idiopathic scoliosis.

    Science.gov (United States)

    Yagi, Mitsuru; Takemitsu, Masakazu; Machida, Masafumi

    2013-09-01

    Retrospective case series of surgically treated adolescent patients with scoliosis. To assess the prevalence and independent risk factors for postoperative shoulder imbalance in surgically treated adolescent patients with idiopathic scoliosis. Despite recent reports that have identified risk factors for postoperative shoulder imbalance, the relative risks remain unclear. A retrospective review of 85 consecutive patients treated with thoracic fusion with a minimum 2-year follow-up (mean, 3.1 yr) was conducted to investigate the patient radiographical measurements and demographics. Shoulder height difference (SHD) was measured as the graded height difference of the soft tissue shadows. A SHD more than 2 cm indicated an unbalanced shoulder. Patient demographics and radiographical data were studied to determine risk factors for postoperative SHD. The potential risk factors included age, sex, Risser sign, Cobb angle, flexibility, and apical vertebral rotation (AVR) of the main curve, upper-instrumented vertebra level, SHD, and clavicle chest cage angle difference (CCAD). Univariate and multivariate logistic regression analyses were performed to determine the independent risk factors for postoperative shoulder imbalance. Of the 85 patients, 21 patients presented postoperative shoulder imbalance. The univariate analysis indicated age, Risser sign, Cobb angle of the main curve, AVR of the main curve, and CCAD as risk factors, but the multivariate logistic regression analysis showed that only AVR of the main curve and CCAD were independent risk factors for postoperative shoulder imbalance (AVR, P = 0.04, odds ratio (OR): 3.54; CCAD, P = 0.01, OR: 5.10). Postoperative shoulder imbalance was observed in 25% of the surgically treated adolescent patients. The CCAD and AVR of the main thoracic curve were independent risk factors for postoperative shoulder imbalance in surgically treated patients with adolescent idiopathic scoliosis. The significant correlation between CCAD and

  3. Transforming growth factor-β1/Smad/connective tissue growth factor axis: The main pathway in radiation-induced fibrosis of osteoradionecrosis?

    Directory of Open Access Journals (Sweden)

    Qian Wei Zhuang

    2013-01-01

    Full Text Available Introduction: Osteoradionecrosis (ORN of the mandible is a serious complication following radiation therapy for malignancies of the head and neck. Radiation-induced fibrosis (RIF is a new theory that accounts for the damage to normal tissues after radiotherapy, and the radiation-induced fibroatrophic mechanism includes the free-radical formation, endothelial dysfunction, inflammation, microvascular thrombosis, fibrosis and remodeling, and finally bone and tissue necrosis. The Hypothesis: Previous studies revealed that transforming growth factor-β1 (TGF-β1 is the master switch cytokine responsible for the regulation of fibroblast proliferation and differentiation that result in RIF. Among the targets of TGF-β1, connective tissue growth factor (CTGF is a downstream mediator through the Smad3/4 pathway and plays an important role in connective tissue homeostasis and fibroblast proliferation. Studies have proved that the TGF-β1/Smad/CTGF signaling pathway is involved in the RIF of soft tissues, so the authors put forward a hypothesis that the TGF-β1/Smad/CTGF axis is also the main pathway in RIF of ORN. Evaluation of the Hypothesis: The validation of our hypothesis may provide new insights for better understanding the pathogenesis of ORN and open new perspectives for anti-fibrotic therapies, and pioneer novel approaches to treat ORN.

  4. When stress and development go hand in hand: main hormonal controls of adventitious rooting in cuttings.

    Science.gov (United States)

    da Costa, Cibele T; de Almeida, Márcia R; Ruedell, Carolina M; Schwambach, Joseli; Maraschin, Felipe S; Fett-Neto, Arthur G

    2013-01-01

    Adventitious rooting (AR) is a multifactorial response leading to new roots at the base of stem cuttings, and the establishment of a complete and autonomous plant. AR has two main phases: (a) induction, with a requirement for higher auxin concentration; (b) formation, inhibited by high auxin and in which anatomical changes take place. The first stages of this process in severed organs necessarily include wounding and water stress responses which may trigger hormonal changes that contribute to reprogram target cells that are competent to respond to rooting stimuli. At severance, the roles of jasmonate and abscisic acid are critical for wound response and perhaps sink strength establishment, although their negative roles on the cell cycle may inhibit root induction. Strigolactones may also inhibit AR. A reduced concentration of cytokinins in cuttings results from the separation of the root system, whose tips are a relevant source of these root induction inhibitors. The combined increased accumulation of basipetally transported auxins from the shoot apex at the cutting base is often sufficient for AR in easy-to-root species. The role of peroxidases and phenolic compounds in auxin catabolism may be critical at these early stages right after wounding. The events leading to AR strongly depend on mother plant nutritional status, both in terms of minerals and carbohydrates, as well as on sink establishment at cutting bases. Auxins play a central role in AR. Auxin transporters control auxin canalization to target cells. There, auxins act primarily through selective proteolysis and cell wall loosening, via their receptor proteins TIR1 (transport inhibitor response 1) and ABP1 (Auxin-Binding Protein 1). A complex microRNA circuitry is involved in the control of auxin response factors essential for gene expression in AR. After root establishment, new hormonal controls take place, with auxins being required at lower concentrations for root meristem maintenance and cytokinins

  5. Analyzing the effect of selected control policy measures and sociodemographic factors on alcoholic beverage consumption in Europe within the AMPHORA project: statistical methods.

    Science.gov (United States)

    Baccini, Michela; Carreras, Giulia

    2014-10-01

    This paper describes the methods used to investigate variations in total alcoholic beverage consumption as related to selected control intervention policies and other socioeconomic factors (unplanned factors) within 12 European countries involved in the AMPHORA project. The analysis presented several critical points: presence of missing values, strong correlation among the unplanned factors, long-term waves or trends in both the time series of alcohol consumption and the time series of the main explanatory variables. These difficulties were addressed by implementing a multiple imputation procedure for filling in missing values, then specifying for each country a multiple regression model which accounted for time trend, policy measures and a limited set of unplanned factors, selected in advance on the basis of sociological and statistical considerations are addressed. This approach allowed estimating the "net" effect of the selected control policies on alcohol consumption, but not the association between each unplanned factor and the outcome.

  6. Identifying and controlling a multiresistant pseudomonas aeruginosa outbreak in a latin-american cancer centre and its associated risk factors

    Directory of Open Access Journals (Sweden)

    Jorge Alberto Cortes

    Full Text Available Pseudomonas aeruginosa is an important and frightening microorganism for patients suffering from cancer. Multiresistant P. aeruginosa (MRPA may appear as a consequence of exposure to multiple antibiotics or from a breakdown in infection control practices. This article reports an MRPA outbreak in a cancer treatment centre and the consequent case control study. Mechanical ventilation was identified as being the main risk factor for developing MRPA colonisation or infection; molecular analysis confirmed the outbreak. A multifaceted strategy was adopted, involving reinforcing hand-washing practices, contact isolation, antibiotic restriction and suction devices for mechanically-ventilated patients. MRPA was controlled and the outbreak ended. Such strategy may be effective in controlling MRPS in low-resource environments amongst high risk cancer patients.

  7. Decontamination of main coolant pumps

    International Nuclear Information System (INIS)

    Roofthooft, R.

    1988-01-01

    Last year a number of main coolant pumps in Belgian nuclear power plants were decontaminated. A new method has been developed to reduce the time taken for decontamination and the volume of waste to be treated. The method comprises two phases: Oxidation with permanganate in nitric acid and dissolution in oxalic acid. The decontamination of main coolant pumps can now be achieved in less than one day. The decontamination factors attained range between 15 and 150. (orig.) [de

  8. Development of staffing evaluation principle for advanced main control room and the effect on situation awareness and mental workload

    International Nuclear Information System (INIS)

    Lin, Chiuhsiang Joe; Hsieh, Tsung-Ling; Lin, Shiau-Feng

    2013-01-01

    Highlights: • A staffing evaluation principle was developed for the advanced main control room. • The principle proposed to improve situation awareness and mental workload. • The principle has good validity that was examined by experimental design. - Abstract: Situation awareness and mental workload, both of which influence operator performance in the advanced main control room of a nuclear power plant, can be affected by staffing level. The key goal of staffing is to ensure the proper number of personnel to support plant operations and events. If the staffing level is not adaptive, the operators may have low situation awareness and an excessive mental workload, which lead to human error. Accordingly, this study developed a staffing evaluation principle based on CPM-GOMS modeling for operations in the advanced main control room. A within-subject experiment was designed to examine the validity of the staffing evaluation principle. The results indicated that the situation awareness, mental workload, and operating performance of the staffing level determined by the staffing evaluation principle was significantly better than that of the non-evaluated staffing level; thus, the validity of the staffing evaluation technique is acceptable. The implications of the findings of this study on managerial practice are discussed

  9. Development of staffing evaluation principle for advanced main control room and the effect on situation awareness and mental workload

    Energy Technology Data Exchange (ETDEWEB)

    Lin, Chiuhsiang Joe, E-mail: cjoelin@mail.ntust.edu.tw [Department of Industrial Management, National Taiwan University of Science and Technology, 43, Section 4, Keelung Road, Taipei 10607, Taiwan (China); Hsieh, Tsung-Ling, E-mail: bm1129@gmail.com [Institute of Nuclear Energy Research, 1000, Wenhua Road, Chiaan Village, Lungtan 32546, Taiwan (China); Lin, Shiau-Feng, E-mail: g9602411@cycu.edu.tw [Department of Industrial Engineering, Chung-Yuan Christian University, 200, Chung Pei Road, Chung-Li 32023, Taiwan (China)

    2013-12-15

    Highlights: • A staffing evaluation principle was developed for the advanced main control room. • The principle proposed to improve situation awareness and mental workload. • The principle has good validity that was examined by experimental design. - Abstract: Situation awareness and mental workload, both of which influence operator performance in the advanced main control room of a nuclear power plant, can be affected by staffing level. The key goal of staffing is to ensure the proper number of personnel to support plant operations and events. If the staffing level is not adaptive, the operators may have low situation awareness and an excessive mental workload, which lead to human error. Accordingly, this study developed a staffing evaluation principle based on CPM-GOMS modeling for operations in the advanced main control room. A within-subject experiment was designed to examine the validity of the staffing evaluation principle. The results indicated that the situation awareness, mental workload, and operating performance of the staffing level determined by the staffing evaluation principle was significantly better than that of the non-evaluated staffing level; thus, the validity of the staffing evaluation technique is acceptable. The implications of the findings of this study on managerial practice are discussed.

  10. AN APPRAISAL OF FACTORS RESPONSIBLE FOR ERRORS IN ...

    African Journals Online (AJOL)

    Osondu

    2013-01-11

    Jan 11, 2013 ... management and clients are the main factors responsible for them. However, the collective .... planning/programming, stress, repetitive tasks. (Shelton, 1999) ... concurrent working control, communications) and global factors ...

  11. Intervention for children exposed to interparental violence : A randomized controlled trial of effectiveness of specific factors, moderators and mediators in community-based intervention

    NARCIS (Netherlands)

    Overbeek, M.M.

    2014-01-01

    The main aim of this thesis was to evaluate the added benefit of applying specific factors in community-based intervention for child witnesses of interparental violence (IPV) and their parents, by means of a randomized controlled trial (RCT). The results of this RCT showed no additional benefits of

  12. Use of a twin dataset to identify AMD-related visual patterns controlled by genetic factors

    Science.gov (United States)

    Quellec, Gwénolé; Abràmoff, Michael D.; Russell, Stephen R.

    2010-03-01

    The mapping of genotype to the phenotype of age-related macular degeneration (AMD) is expected to improve the diagnosis and treatment of the disease in a near future. In this study, we focused on the first step to discover this mapping: we identified visual patterns related to AMD which seem to be controlled by genetic factors, without explicitly relating them to the genes. For this purpose, we used a dataset of eye fundus photographs from 74 twin pairs, either monozygotic twins, who have the same genotype, or dizygotic twins, whose genes responsible for AMD are less likely to be identical. If we are able to differentiate monozygotic twins from dizygotic twins, based on a given visual pattern, then this pattern is likely to be controlled by genetic factors. The main visible consequence of AMD is the apparition of drusen between the retinal pigment epithelium and Bruch's membrane. We developed two automated drusen detectors based on the wavelet transform: a shape-based detector for hard drusen, and a texture- and color- based detector for soft drusen. Forty visual features were evaluated at the location of the automatically detected drusen. These features characterize the texture, the shape, the color, the spatial distribution, or the amount of drusen. A distance measure between twin pairs was defined for each visual feature; a smaller distance should be measured between monozygotic twins for visual features controlled by genetic factors. The predictions of several visual features (75.7% accuracy) are comparable or better than the predictions of human experts.

  13. Comparison of atherogenic risk factors among poorly controlled and well-controlled adolescent phenylketonuria patients.

    Science.gov (United States)

    Gündüz, Mehmet; Çakar, Sevim; Kuyum, Pınar; Makay, Balahan; Arslan, Nur

    2016-06-01

    Previous studies investigating the known risk factors of atherosclerosis in phenylketonuria patients have shown conflicting results. The primary aim of our study was to investigate the serum atherogenic markers in adolescent classical phenylketonuria patients and compare these parameters with healthy peers. The secondary aim was to compare these atherogenic markers in well-controlled and poorly controlled patients. A total of 59 patients (median age: 12.6 years, range: 11-17 years) and 44 healthy controls (median age: 12.0 years, range: 11-15 years) were enrolled in our study. Phenylketonuria patients were divided into two groups: well-controlled (serum phenylalanine levels below 360 µmol/L; 24 patients) and poorly controlled patients (serum phenylalanine levels higher than 360 µmol/L). The mean high-density lipoprotein cholesterol levels of well-controlled patients (1.0±0.2 mmol/L) were significantly lower compared with poorly controlled patients and controls (1.1±0.2 mmol/L, p=0.011 and 1.4±0.2 mmol/L, pphenylketonuria patients. In particular, these changes were more prominent in well-controlled patients. We conclude that phenylketonuria patients might be at risk for atherosclerosis, and therefore screening for atherosclerotic risk factors should be included in the phenylketonuria therapy and follow-up in addition to other parameters.

  14. Evaluating risk factors for protein-energy malnutrition in children under the age of six years: a case-control study from Iran

    Directory of Open Access Journals (Sweden)

    Sharghi A

    2011-08-01

    Full Text Available Afshan Sharghi1, Aziz Kamran2, Mohammad Faridan31Department of Community Medicine, Medical School, Ardebil University of Medical Sciences, Ardebil, 2Department of Public Health, Faculty of Health, Isfahan University of Medical Sciences, Isfahan, 3Department of Public Health, Faculty of Health, Lorestan University of Medical Sciences, Lorestan, IranIntroduction: Protein-energy malnutrition is one of the most important public health problems in Iran. It not only accounts for more than half of child mortality but can also produce somatic and mental impairment in survivors. The main aim of this study was to identify risk factors for protein-energy malnutrition in children under 6 years of age in Namin city.Methods: This was a population-based, multicenter case-control study. Seventy-six children with malnutrition and 76 children without malnutrition were randomly recruited for case and control groups. The prevalence of risk factors in the two groups was compared. Data were gathered from a health center database and interviews with mothers and health workers. The Wilcoxon signed-rank test and logistic regression were used for data analysis.Results: Female gender, poverty, short maternal height, and use of unhygienic latrines in the home were significantly associated with childhood malnutrition (P , 0.05.Conclusion: The results of this study indicate four main factors (poverty, small maternal height, female gender, and absence of hygienic latrines in the home as underlying factors in malnutrition of children under the age of 6 years.Keywords: protein-energy malnutrition, children, risk factors, Namin

  15. Factors Controlling Nitrogen Fluxes in Groundwater in Agricultural Areas

    Science.gov (United States)

    Liao, L.; Green, C. T.; Bekins, B. A.; Bohlke, J. K.

    2010-12-01

    Predictions of effects of land use changes on water quality require identification of the relative importance of geochemical and hydrologic factors. To understand the factors controlling the transport of nitrogen in groundwater, vertical fluxes of water and solutes were estimated for 13 aquifers in agricultural areas located in California, Iowa, Maryland, Minnesota, Mississippi, Nebraska, North Carolina, Texas, and Wisconsin. The aquifers are overlain by unsaturated zones with thicknesses ranging from 2.5 to 100 m. Precipitation ranges from 19 to 132 cm/yr and irrigation ranges from 0 to 120 cm/yr. Main crop types include corn, soybeans, forage, wheat, and cotton. A 1-dimensional mathematical model was developed to estimate vertical N transport in response to N inputs on the land surface from chemical fertilizer, manure and atmospheric deposition. Simulated vertical profiles of O2, NO3-, N2 from denitrification, Cl- and atmospheric age tracers were matched to observations by adjusting parameters for recharge rate, unsaturated zone travel time, N leaching ratio (defined as leaching fraction of N reaching water table of N input at land surface), Cl- leaching ratio, O2 reduction rate and denitrification rate. Results indicated that vertical NO3 fluxes below the water table were affected by both geochemical and physical factors. High vertical NO3 fluxes below the water table are associated with high N input at the land surface. Values of Cl- leaching ratios were less than 1 (0.42 to 1) likely as a result of runoff and exported harvested crops. N leaching ratios were lower (0.1 to 0.6), consistent with additional N losses such as denitrification and volatilization. The sites with high leaching ratios for both N and Cl tended to be those with high recharge rates and low ET loss, defined as the fraction of applied water lost to ET. Modeled zero-order denitrification rates in the saturated zone varied within an order of magnitude with a maximum rate of 1.6 mg

  16. An empirical study on the basic human error probabilities for NPP advanced main control room operation using soft control

    International Nuclear Information System (INIS)

    Jang, Inseok; Kim, Ar Ryum; Harbi, Mohamed Ali Salem Al; Lee, Seung Jun; Kang, Hyun Gook; Seong, Poong Hyun

    2013-01-01

    Highlights: ► The operation environment of MCRs in NPPs has changed by adopting new HSIs. ► The operation action in NPP Advanced MCRs is performed by soft control. ► Different basic human error probabilities (BHEPs) should be considered. ► BHEPs in a soft control operation environment are investigated empirically. ► This work will be helpful to verify if soft control has positive or negative effects. -- Abstract: By adopting new human–system interfaces that are based on computer-based technologies, the operation environment of main control rooms (MCRs) in nuclear power plants (NPPs) has changed. The MCRs that include these digital and computer technologies, such as large display panels, computerized procedures, soft controls, and so on, are called Advanced MCRs. Among the many features in Advanced MCRs, soft controls are an important feature because the operation action in NPP Advanced MCRs is performed by soft control. Using soft controls such as mouse control, touch screens, and so on, operators can select a specific screen, then choose the controller, and finally manipulate the devices. However, because of the different interfaces between soft control and hardwired conventional type control, different basic human error probabilities (BHEPs) should be considered in the Human Reliability Analysis (HRA) for advanced MCRs. Although there are many HRA methods to assess human reliabilities, such as Technique for Human Error Rate Prediction (THERP), Accident Sequence Evaluation Program (ASEP), Human Error Assessment and Reduction Technique (HEART), Human Event Repository and Analysis (HERA), Nuclear Computerized Library for Assessing Reactor Reliability (NUCLARR), Cognitive Reliability and Error Analysis Method (CREAM), and so on, these methods have been applied to conventional MCRs, and they do not consider the new features of advance MCRs such as soft controls. As a result, there is an insufficient database for assessing human reliabilities in advanced

  17. Simplifying the audit of risk factor recording and control

    DEFF Research Database (Denmark)

    Zhao, Min; Cooney, Marie Therese; Klipstein-Grobusch, Kerstin

    2016-01-01

    BACKGROUND: To simplify the assessment of the recording and control of coronary heart disease risk factors in different countries and regions. DESIGN: The SUrvey of Risk Factors (SURF) is an international clinical audit. METHODS: Data on consecutive patients with established coronary heart disease...

  18. Case control study to identify risk factors for acute hepatitis C virus infection in Egypt

    Directory of Open Access Journals (Sweden)

    Kandeel Amr M

    2012-11-01

    Full Text Available Abstract Background Identification of risk factors of acute hepatitis C virus (HCV infection in Egypt is crucial to develop appropriate prevention strategies. Methods We conducted a case–control study, June 2007-September 2008, to investigate risk factors for acute HCV infection in Egypt among 86 patients and 287 age and gender matched controls identified in two infectious disease hospitals in Cairo and Alexandria. Case-patients were defined as: any patient with symptoms of acute hepatitis; lab tested positive for HCV antibodies and negative for HBsAg, HBc IgM, HAV IgM; and 7-fold increase in the upper limit of transaminase levels. Controls were selected from patients’ visitors with negative viral hepatitis markers. Subjects were interviewed about previous exposures within six months, including community-acquired and health-care associated practices. Results Case-patients were more likely than controls to have received injection with a reused syringe (OR=23.1, CI 4.7-153, to have been in prison (OR=21.5, CI 2.5-479.6, to have received IV fluids in a hospital (OR=13.8, CI 5.3-37.2, to have been an IV drug user (OR=12.1, CI 4.6-33.1, to have had minimal surgical procedures (OR=9.7, CI 4.2-22.4, to have received IV fluid as an outpatient (OR=8, CI 4–16.2, or to have been admitted to hospital (OR=7.9, CI 4.2-15 within the last 6 months. Multivariate analysis indicated that unsafe health facility practices are the main risk factors associated with transmission of HCV infection in Egypt. Conclusion In Egypt, focusing acute HCV prevention measures on health-care settings would have a beneficial impact.

  19. An investigation of breast cancer risk factors in Cyprus: a case control study

    Directory of Open Access Journals (Sweden)

    Hadjisavvas Andreas

    2010-08-01

    Full Text Available Abstract Background Breast cancer is the most common form of malignancy affecting women worldwide. It is also the leading cancer in females in Cyprus, with approximately 400 new cases diagnosed annually. It is well recognized that genetic variation as well as environmental factors modulate breast cancer risk. The main aim of this study was to assess the strength of associations between recognized risk factors and breast cancer among Cypriot women. This is the first epidemiological investigation on risk factors of breast cancer among the Cypriot female population. Methods We carried out a case-control study, involving 1,109 breast cancer patients and a group of 1,177 controls who were recruited while participating in the National screening programme for breast cancer. Information on demographic characteristics and potential risk factors were collected from both groups during a standardized interview. Logistic regression analysis was used to assess the strength of the association between each risk factor and breast cancer risk, before and after adjusting for the possible confounding effect of other factors. Results In multivariable models, family history of breast cancer (OR 1.64, 95% CI 1.23, 2.19 was the strongest predictor of breast cancer risk in the Cypriot population. Late menarche (OR 0.64, 95% CI 0.45, 0.92 among women reaching menarche after the age of 15 vs. before the age of 12 and breastfeeding (OR 0.74, 95% CI 0.59, 0.92 exhibited a strong protective effect. In the case of breastfeeding, the observed effect appeared stronger than the effect of pregnancy alone. Surprisingly, we also observed an inverse association between hormone replacement therapy (HRT although this may be a product of the retrospective nature of this study. Conclusion Overall the findings of our study corroborate with the results of previous investigations on descriptive epidemiology of risk factors for breast cancer. This investigation provides important background

  20. The Ergonomically Principle Application On The Main Control Room At Modified Research Reactor TRIGA Mark II

    International Nuclear Information System (INIS)

    Santoso, Kussigit; Itjeu K; Piping S; Sudarmin; Bambang S; Suharyo W

    2000-01-01

    The main control room analysis has been done by using the application of ergonomically principle. The analysis has been stressed on the controller position and noisiness and lightness. The instrumentation position has been analyzed by using software DAP (Display Analysis Program) and noisiness and brightness has been measured by direct measurement at definite point. From the result, it is known that the analog panel display is not good, then it is advised to rearrange the data element and the character vertically or horizontally for reducing the position character complexities. From the noisiness and brightness measurement, it is know that it still fulfills the safety standard

  1. Research on characteristics of communication content of operation crew in digital main control room of nuclear power plant

    International Nuclear Information System (INIS)

    Zhang Li; Ye Haifeng; Qing Tao; Li Pengcheng

    2015-01-01

    Communication content, communication mode and timeliness of communication are the main three factors that influence the effectiveness of the communication between team members. Based on the work domain analysis to execution of state-oriented procedures (SOP), the assumptions for operation crews' characteristics of the communication content in executing SOP were proposed, which supposed that the power plant status and parameters, power plant system functions and equipment, and SOP as well were the main communication contents. On a full-scope simulator of nuclear power plant, three operation crews performed experiments simulating accident scenarios. The results show that the assumptions of characteristics of the communication content are valid. (authors)

  2. Evaluation on the Effect of Load Follow Controller's Weighting Factors

    Energy Technology Data Exchange (ETDEWEB)

    Yu, Keuk Jong; Lee, Jae Gon [KHNP CRI, Daejeon (Korea, Republic of)

    2016-10-15

    there are several important physical effects that limit the possibilities of power variations in NPPs. Some major effects are moderator and xenon effect. Moderator effect is relation with moderator density change and xenon effect is relation with the concentration change of Xe-135 which could affect axial power shape. These effects are more significant with large magnitudes of power variations and they are considered as major disturbances at the aspect of control method. Due to the above physical effects, it is necessary to carefully change nuclear power considering power distribution change in the core. So, when nuclear plants are required to operate on load variation mode, we could control not only reactor power but also power distribution. Generally, power distribution is controlled by reactor operators who have enough experience, whereas reactor power is automatically controlled by automatic controllers. So, it is necessary to design an automatic controller that controls both reactor power and power distribution for frequent load following operation. Korea Hydro and Nuclear Power Co., LTD (KHNP) has been developing automatic load follow controller as a part of Advanced Power Reactor Plus (APR+) development. The developing controller is composed of three algorithms which could control reactor power and axial power shape. This paper aimed to evaluate the effect of the controller’s weighting factors. So, in this paper, we identify the meaning of the weighting factors and the controlled output weighting factors are selected among them. In this study, the effect of output weighting factors is analyzed. According to the simulation results, it is recommended that the weighting factor of power be between 200 and 400 and that of ASI be between 200 and 600. In the near future, based on the study, optimization of power and ASI weighting factors will be performed at the same time.

  3. What are the Main Risk Factors for Running-Related Injuries?

    NARCIS (Netherlands)

    Saragiotto, B.T.; Yamato, T.P.; Hespanhol, L.C.; Rainbow, M.J.; Davis, I.S.; Lopes, A.D.

    2014-01-01

    Background: Despite several studies that have been conducted on running injuries, the risk factors for running-related injuries are still not clear in the literature. Objective: The aim of this study was to systematically review prospective cohort studies that investigated the risk factors for

  4. Factors controlling volume errors through 2D gully erosion assessment: guidelines for optimal survey design

    Science.gov (United States)

    Castillo, Carlos; Pérez, Rafael

    2017-04-01

    The assessment of gully erosion volumes is essential for the quantification of soil losses derived from this relevant degradation process. Traditionally, 2D and 3D approaches has been applied for this purpose (Casalí et al., 2006). Although innovative 3D approaches have recently been proposed for gully volume quantification, a renewed interest can be found in literature regarding the useful information that cross-section analysis still provides in gully erosion research. Moreover, the application of methods based on 2D approaches can be the most cost-effective approach in many situations such as preliminary studies with low accuracy requirements or surveys under time or budget constraints. The main aim of this work is to examine the key factors controlling volume error variability in 2D gully assessment by means of a stochastic experiment involving a Monte Carlo analysis over synthetic gully profiles in order to 1) contribute to a better understanding of the drivers and magnitude of gully erosion 2D-surveys uncertainty and 2) provide guidelines for optimal survey designs. Owing to the stochastic properties of error generation in 2D volume assessment, a statistical approach was followed to generate a large and significant set of gully reach configurations to evaluate quantitatively the influence of the main factors controlling the uncertainty of the volume assessment. For this purpose, a simulation algorithm in Matlab® code was written, involving the following stages: - Generation of synthetic gully area profiles with different degrees of complexity (characterized by the cross-section variability) - Simulation of field measurements characterised by a survey intensity and the precision of the measurement method - Quantification of the volume error uncertainty as a function of the key factors In this communication we will present the relationships between volume error and the studied factors and propose guidelines for 2D field surveys based on the minimal survey

  5. Factors associated with suicide: Case-control study in South Tyrol.

    Science.gov (United States)

    Giupponi, Giancarlo; Innamorati, Marco; Baldessarini, Ross J; De Leo, Diego; de Giovannelli, Francesca; Pycha, Roger; Conca, Andreas; Girardi, Paolo; Pompili, Maurizio

    2018-01-01

    As suicide is related to many factors in addition to psychiatric illness, broad and comprehensive risk-assessment for risk of suicide is required. This study aimed to differentiate nondiagnostic risk factors among suicides versus comparable psychiatric patients without suicidal behavior. We carried out a pilot, case-control comparison of 131 cases of suicide in South Tyrol matched for age and sex with 131 psychiatric controls, using psychological autopsy methods to evaluate differences in clinically assessed demographic, social, and clinical factors, using bivariate conditional Odds Risk comparisons followed by conditional regression modeling controlled for ethnicity. Based on multivariable conditional regression modeling, suicides were significantly more likely to have experienced risk factors, ranking as: [a] family history of suicide or attempt≥[b] recent interpersonal stressors≥[c] childhood traumatic events≥[d] lack of recent clinician contacts≥[e] previous suicide attempt≥[f] non-Italian ethnicity, but did not differ in education, marital status, living situation, or employment, nor by psychiatric or substance-abuse diagnoses. Both recent and early factors were associated with suicide, including lack of recent clinical care, non-Italian cultural subgroup-membership, familial suicidal behavior, and recent interpersonal distress. Copyright © 2017 Elsevier Inc. All rights reserved.

  6. Underlying Factors for Practicality of the Production Control Systems

    DEFF Research Database (Denmark)

    Arica, Emrah; Strandhagen, Jan Ola; Hvolby, Hans-Henrik

    2012-01-01

    and communication technology, coordination and feedback, human factors and decision making, and measurement are the identified factors to be taken into account. Industrial interviews with three case companies, that are participating to the research program called The Norwegian Manufacturing Future (SFI NORMAN......This paper gives indications to important factors that must be considered for effectiveness of the production control systems under uncertainty. Five key factors have been identified by the literature study. Production schedule generation and execution approach under uncertainty, information...

  7. Risk factors for measles among adults in Tianjin, China: Who should be controls in a case-control study?

    Science.gov (United States)

    Wagner, Abram L; Boulton, Matthew L; Gillespie, Brenda W; Zhang, Ying; Ding, Yaxing; Carlson, Bradley F; Luo, Xiaoyan; Montgomery, JoLynn P; Wang, Xiexiu

    2017-01-01

    Control groups in previous case-control studies of vaccine-preventable diseases have included people immune to disease. This study examines risk factors for measles acquisition among adults 20 to 49 years of age in Tianjin, China, and compares findings using measles IgG antibody-negative controls to all controls, both IgG-negative and IgG-positive. Measles cases were sampled from a disease registry, and controls were enrolled from community registries in Tianjin, China, 2011-2015. Through a best subsets selection procedure, we compared which variables were selected at different model sizes when using IgG-negative controls or all controls. We entered risk factors for measles in two separate logistic regression models: one with measles IgG-negative controls and the other with all controls. The study included 384 measles cases and 1,596 community controls (194 IgG-negative). Visiting a hospital was an important risk factor. For specialty hospitals, the odds ratio (OR) was 4.53 (95% confidence interval (CI): 1.28, 16.03) using IgG-negative controls, and OR = 5.27 (95% CI: 2.73, 10.18) using all controls. Variables, such as age or length of time in Tianjin, were differentially selected depending on the control group. Individuals living in Tianjin ≤3 years had 2.87 (95% CI: 1.46, 5.66) times greater odds of measles case status compared to all controls, but this relationship was not apparent for IgG-negative controls. We recommend that case-control studies examining risk factors for infectious diseases, particularly in the context of transmission dynamics, consider antibody-negative controls as the gold standard.

  8. Performance related factors are the main determinants of the von Willebrand factor response to exhaustive physical exercise.

    Directory of Open Access Journals (Sweden)

    Janine E van Loon

    Full Text Available Physical stress triggers the endothelium to release von Willebrand Factor (VWF from the Weibel Palade bodies. Since VWF is a risk factor for arterial thrombosis, it is of great interest to discover determinants of VWF response to physical stress. We aimed to determine the main mediators of the VWF increase by exhaustive physical exercise.105 healthy individuals (18-35 years were included in this study. Each participant performed an incremental exhaustive exercise test on a cycle ergometer. Respiratory gas exchange measurements were obtained while cardiac function was continuously monitored. Blood was collected at baseline and directly after exhaustion. VWF antigen (VWF:Ag levels, VWF collagen binding (VWF:CB levels, ADAMTS13 activity and common variations in Syntaxin Binding Protein-5 (STXBP5, rs1039084 and rs9399599, Syntaxin-2 (STX2, rs7978987 and VWF (promoter, rs7965413 were determined.The median VWF:Ag level at baseline was 0.94 IU/mL [IQR 0.8-1.1] and increased with 47% [IQR 25-73] after exhaustive exercise to a median maximum VWF:Ag of 1.38 IU/mL [IQR 1.1-1.8] (p<0.0001. VWF:CB levels and ADAMTS13 activity both also increased after exhaustive exercise (median increase 43% and 12%, both p<0.0001. The strongest determinants of the VWF:Ag level increase are performance related (p<0.0001. We observed a gender difference in VWF:Ag response to exercise (females 1.2 IU/mL; males 1.7 IU/mL, p = 0.001, which was associated by a difference in performance. Genetic variations in STXBP5, STX2 and the VWF promoter were not associated with VWF:Ag levels at baseline nor with the VWF:Ag increase.VWF:Ag levels strongly increase upon exhaustive exercise and this increase is strongly determined by physical fitness level and the intensity of the exercise, while there is no clear effect of genetic variation in STXBP5, STX2 and the VWF promoter.

  9. Risk factors for syphilis in women: case-control study

    Directory of Open Access Journals (Sweden)

    Vilma Costa de Macêdo

    2017-08-01

    Full Text Available ABSTRACT OBJECTIVE To determine the sociodemographic, behavioral, and health care factors related to the occurrence of syphilis in women treated at public maternity hospitals. METHODS This is a case-control study (239 cases and 322 controls with women admitted to seven maternity hospitals in the municipality of Recife, Brazil, from July 2013 to July 2014. Eligible women were recruited after the result of the VDRL (Venereal Disease Research Laboratory under any titration. The selection of cases and controls was based on the result of the serology for syphilis using ELISA (enzyme-linked immunosorbent assay. The independent variables were grouped into: sociodemographic, behavioral, clinical and obstetric history, and health care in prenatal care and maternity hospital. Information was obtained by interview, during hospitalization, with the application of a questionnaire. Odds ratios and 95% confidence intervals were estimated using logistic regression to identify the predicting factors of the variable to be explained. RESULTS The logistic regression analysis identified as determinant factors for gestational syphilis: education level of incomplete basic education or illiterate (OR = 2.02, lack of access to telephone (OR = 2.4, catholic religion (OR = 1.70 , four or more pregnancies (OR = 2.2, three or more sexual partners in the last year (OR = 3.1, use of illicit drugs before the age of 18 (OR = 3.0, and use of illicit drugs by the current partner (OR = 1.7. Only one to three prenatal appointments (OR = 3.5 and a previous history of sexually transmitted infection (OR = 9.7 were also identified as determinant factors. CONCLUSIONS Sociodemographic, behavioral, and health care factors are associated with the occurrence of syphilis in women and should be taken into account in the elaboration of universal strategies aimed at the prevention and control of syphilis, but with a focus on situations of greater vulnerability.

  10. Risk factors for syphilis in women: case-control study

    Science.gov (United States)

    de Macêdo, Vilma Costa; de Lira, Pedro Israel Cabral; de Frias, Paulo Germano; Romaguera, Luciana Maria Delgado; Caires, Silvana de Fátima Ferreira; Ximenes, Ricardo Arraes de Alencar

    2017-01-01

    ABSTRACT OBJECTIVE To determine the sociodemographic, behavioral, and health care factors related to the occurrence of syphilis in women treated at public maternity hospitals. METHODS This is a case-control study (239 cases and 322 controls) with women admitted to seven maternity hospitals in the municipality of Recife, Brazil, from July 2013 to July 2014. Eligible women were recruited after the result of the VDRL (Venereal Disease Research Laboratory) under any titration. The selection of cases and controls was based on the result of the serology for syphilis using ELISA (enzyme-linked immunosorbent assay). The independent variables were grouped into: sociodemographic, behavioral, clinical and obstetric history, and health care in prenatal care and maternity hospital. Information was obtained by interview, during hospitalization, with the application of a questionnaire. Odds ratios and 95% confidence intervals were estimated using logistic regression to identify the predicting factors of the variable to be explained. RESULTS The logistic regression analysis identified as determinant factors for gestational syphilis: education level of incomplete basic education or illiterate (OR = 2.02), lack of access to telephone (OR = 2.4), catholic religion (OR = 1.70 ), four or more pregnancies (OR = 2.2), three or more sexual partners in the last year (OR = 3.1), use of illicit drugs before the age of 18 (OR = 3.0), and use of illicit drugs by the current partner (OR = 1.7). Only one to three prenatal appointments (OR = 3.5) and a previous history of sexually transmitted infection (OR = 9.7) were also identified as determinant factors. CONCLUSIONS Sociodemographic, behavioral, and health care factors are associated with the occurrence of syphilis in women and should be taken into account in the elaboration of universal strategies aimed at the prevention and control of syphilis, but with a focus on situations of greater vulnerability. PMID:28832758

  11. Potential risk factors for diabetic neuropathy: a case control study

    Directory of Open Access Journals (Sweden)

    Nooraei Mahdi

    2005-12-01

    Full Text Available Abstract Background Diabetes mellitus type II afflicts at least 2 million people in Iran. Neuropathy is one of the most common complications of diabetes and lowers the patient's quality of life. Since neuropathy often leads to ulceration and amputation, we have tried to elucidate the factors that can affect its progression. Methods In this case-control study, 110 diabetic patients were selected from the Shariati Hospital diabetes clinic. Michigan Neuropathic Diabetic Scoring (MNDS was used to differentiate cases from controls. The diagnosis of neuropathy was confirmed by nerve conduction studies (nerve conduction velocity and electromyography. The multiple factors compared between the two groups included consumption of angiotensin converting enzyme inhibitors (ACEI, blood pressure, serum lipid level, sex, smoking, method of diabetes control and its quality. Results Statistically significant relationships were found between neuropathy and age, gender, quality of diabetes control and duration of disease (P values in the order: 0.04, 0.04, Conclusion In this study, hyperglycemia was the only modifiable risk factor for diabetic neuropathy. Glycemic control reduces the incidence of neuropathy, slows its progression and improves the diabetic patient's quality of life. More attention must be paid to elderly male diabetic patients with poor diabetes control with regard to regular foot examinations and more practical education.

  12. Human factors design, verification, and validation for two types of control room upgrades at a nuclear power plant

    Energy Technology Data Exchange (ETDEWEB)

    Boring, Laurids Ronald [Idaho National Lab. (INL), Idaho Falls, ID (United States)

    2014-10-01

    This paper describes the NUREG-0711 based human factors engineering (HFE) phases and associated elements required to support design, verification and validation (V&V), and implementation of a new plant process computer (PPC) and turbine control system (TCS) at a representative nuclear power plant. This paper reviews ways to take a human-system interface (HSI) specification and use it when migrating legacy PPC displays or designing displays with new functionality. These displays undergo iterative usability testing during the design phase and then undergo an integrated system validation (ISV) in a full scope control room training simulator. Following the successful demonstration of operator performance with the systems during the ISV, the new system is implemented at the plant, first in the training simulator and then in the main control room.

  13. Human factors design, verification, and validation for two types of control room upgrades at a nuclear power plant

    International Nuclear Information System (INIS)

    Boring, Laurids Ronald

    2014-01-01

    This paper describes the NUREG-0711 based human factors engineering (HFE) phases and associated elements required to support design, verification and validation (V&V), and implementation of a new plant process computer (PPC) and turbine control system (TCS) at a representative nuclear power plant. This paper reviews ways to take a human-system interface (HSI) specification and use it when migrating legacy PPC displays or designing displays with new functionality. These displays undergo iterative usability testing during the design phase and then undergo an integrated system validation (ISV) in a full scope control room training simulator. Following the successful demonstration of operator performance with the systems during the ISV, the new system is implemented at the plant, first in the training simulator and then in the main control room.

  14. Human factors evaluation of the engineering test reactor control room

    International Nuclear Information System (INIS)

    Banks, W.W.; Boone, M.P.

    1981-03-01

    The Reactor and Process Control Rooms at the Engineering Test Reactor were evaluated by a team of human factors engineers using available human factors design criteria. During the evaluation, ETR, equipment and facilities were compared with MIL-STD-1472-B, Human Engineering design Criteria for Military Systems. The focus of recommendations centered on: (a) displays and controls; placing displays and controls in functional groups; (b) establishing a consistent color coding (in compliance with a standard if possible); (c) systematizing annunciator alarms and reducing their number; (d) organizing equipment in functional groups; and (e) modifying labeling and lines of demarcation

  15. Modeling of a dependence between human operators in advanced main control rooms

    International Nuclear Information System (INIS)

    Lee, Seung Jun; Kim, Jaewhan; Jang, Seung-Cheol; Shin, Yeong Cheol

    2009-01-01

    For the human reliability analysis of main control room (MCR) operations, not only parameters such as the given situation and capability of the operators but also the dependence between the actions of the operators should be considered because MCR operations are team operations. The dependence between operators might be more prevalent in an advanced MCR in which operators share the same information using a computerized monitoring system or a computerized procedure system. Therefore, this work focused on the computerized operation environment of advanced MCRs and proposed a model to consider the dependence representing the recovery possibility of an operator error by another operator. The proposed model estimates human error probability values by considering adjustment values for a situation and dependence values for operators during the same operation using independent event trees. This work can be used to quantitatively calculate a more reliable operation failure probability for an advanced MCR. (author)

  16. Design of the control room of the N4-type PWR: main features and feedback operating experience

    International Nuclear Information System (INIS)

    Peyrouton, J.M.; Guillas, J.; Nougaret, Ch.

    2004-01-01

    This article presents the design, specificities and innovating features of the control room of the N4-type PWR. A brief description of control rooms of previous 900 MW and 1300 MW -type PWR allows us to assess the change. The design of the first control room dates back to 1972, at that time 2 considerations were taken into account: first the design has to be similar to that of control rooms for thermal plants because plant operators were satisfied with it and secondly the normal operating situation has to be privileged to the prejudice of accidental situations just as it was in a thermal plant. The turning point was the TMI accident that showed the weight of human factor in accidental situations in terms of pilot team, training, procedures and the ergonomics of the work station. The impact of TMI can be seen in the design of 1300 MW-type PWR. In the beginning of the eighties EDF decided to launch a study for a complete overhaul of the control room concept, the aim was to continue reducing the human factor risk and to provide a better quality of piloting the plant in any situation. The result is the control room of the N4-type PWR. Today the cumulated feedback experience of N4 control rooms represents more than 20 years over a wide range of situations from normal to incidental, a survey shows that the N4 design has fulfilled its aims. (A.C.)

  17. Influence of psychosocial factors on self-care behaviors and glycemic control in Turkish patients with type 2 diabetes mellitus.

    Science.gov (United States)

    Cosansu, Gulhan; Erdogan, Semra

    2014-01-01

    The main purpose of this study was to investigate the direct and indirect effects of psychosocial factors on self-care behavior and glycemic control in Turkish patients with type 2 diabetes mellitus. The study used a cross-sectional questionnaire survey design (N = 350). Data were collected using the Summary of Diabetes Self-Care Activities Scale and the Multidimensional Diabetes Questionnaire. The relationship between the study variables was analyzed using Pearson's correlation coefficient and structural equation modeling. Self-efficacy was associated with social support, outcome expectancies, perceived interference, educational level, and self-care and A1C. According to the structural equation model, self-efficacy was the predictor variable that influenced both self-care and glycemic control. Self-efficacy in achieving desired health outcomes was found to play a central role in Turkish patients. Although interventions are planned and implemented to achieve and maintain self-management in individuals with diabetes, strengthening psychosocial factors, particularly self-efficacy, may contribute to adjustment to disease and good glycemic control in the long term.

  18. Factores de necesidad asociados al uso adecuado del control prenatal

    Directory of Open Access Journals (Sweden)

    Clarybel Miranda Mellado

    2016-07-01

    Full Text Available Introducción: Por las implicaciones sociales de la mortalidad y morbilidad materna es importante determinar los factores de necesidad que influyen en el uso adecuado del control prenatal en gestantes de Sincelejo. Materiales y Métodos: Estudio analítico de corte transversal, que incluyó 730 gestantes, seleccionadas mediante muestreo aleatorio por conglomerados, de las comunas de la ciudad. La información fue recolectada por medio de una encuesta sociodemográfica, una ficha de uso de control prenatal y un Cuestionario para evaluar los factores de necesidad  propuestos por el Modelo de Promoción de la Salud de Nola Pender. Las gestantes fueron contactadas en sus domicilios y diligenciaron los instrumentos. Los datos fueron analizados aplicando estadística descriptiva e inferencial para determinar las asociaciones entre variables. Resultados: El 97,7% (713 de las gestantes asistía al control prenatal, con una mediana de 4 controles prenatales. Un 2,3% (17 no lo habían iniciado al momento de la encuesta y 24,4% (178 hizo uso inadecuado. El 80,7% (589 de las gestantes califican su estado de salud como bueno o muy bueno, 94,8% (692 percibieron beneficios del control prenatal. Se encontró asociación significativa entre la percepción de beneficios y el uso adecuado de control prenatal [OR=5,5 (IC 95%: 2,8 - 10,8]. Discusión y Conclusiones: La percepción que las mujeres tienen sobre los buenos resultados que reporta la asistencia al control prenatal, es el principal factor que puede explicar la adherencia al control y el cumplimiento regular de las consultas. Cómo citar este artículo: Miranda C, Castillo IY. Factores de necesidad asociados al uso adecuado del control prenatal. Rev Cuid. 2016; 7(2: 1345-51. http://dx.doi.org/10.15649/cuidarte.v7i2.340

  19. Controls on mercury and methylmercury deposition for two watersheds in Acadia National Park, Maine.

    Science.gov (United States)

    Johnson, K B; Haines, T A; Kahl, J S; Norton, S A; Amirbahman, Aria; Sheehan, K D

    2007-03-01

    Throughfall and bulk precipitation samples were collected for two watersheds at Acadia National Park, Maine, from 3 May to 16 November 2000, to determine which landscape factors affected mercury (Hg) deposition. One of these watersheds, Cadillac Brook, burned in 1947, providing a natural experimental design to study the effects of forest type on deposition to forested watersheds. Sites that face southwest received the highest Hg deposition, which may be due to the interception of cross-continental movement of contaminated air masses. Sites covered with softwood vegetation also received higher Hg deposition than other vegetation types because of the higher scavenging efficiency of the canopy structure. Methyl mercury (MeHg) deposition was not affected by these factors. Hg deposition, as bulk precipitation and throughfall was lower in Cadillac Brook watershed (burned) than in Hadlock Brook watershed (unburned) because of vegetation type and watershed aspect. Hg and MeHg inputs were weighted by season and vegetation type because these two factors had the most influence on deposition. Hg volatilization was not determined. The total Hg deposition via throughfall and bulk precipitation was 9.4 microg/m(2)/year in Cadillac Brook watershed and 10.2 microg/m(2)/year in Hadlock Brook watershed. The total MeHg deposition via throughfall and bulk precipitation was 0.05 microg/m(2)/year in Cadillac Brook watershed and 0.10 microg/m(2)/year in Hadlock Brook watershed.

  20. Proportional-Integral-Derivative (PID) Control of Secreted Factors for Blood Stem Cell Culture.

    Science.gov (United States)

    Caldwell, Julia; Wang, Weijia; Zandstra, Peter W

    2015-01-01

    Clinical use of umbilical cord blood has typically been limited by the need to expand hematopoietic stem and progenitor cells (HSPC) ex vivo. This expansion is challenging due to the accumulation of secreted signaling factors in the culture that have a negative regulatory effect on HSPC output. Strategies for global regulation of these factors through dilution have been developed, but do not accommodate the dynamic nature or inherent variability of hematopoietic cell culture. We have developed a mathematical model to simulate the impact of feedback control on in vitro hematopoiesis, and used it to design a proportional-integral-derivative (PID) control algorithm. This algorithm was implemented with a fed-batch bioreactor to regulate the concentrations of secreted factors. Controlling the concentration of a key target factor, TGF-β1, through dilution limited the negative effect it had on HSPCs, and allowed global control of other similarly-produced inhibitory endogenous factors. The PID control algorithm effectively maintained the target soluble factor at the target concentration. We show that feedback controlled dilution is predicted to be a more cost effective dilution strategy compared to other open-loop strategies, and can enhance HSPC expansion in short term culture. This study demonstrates the utility of secreted factor process control strategies to optimize stem cell culture systems, and motivates the development of multi-analyte protein sensors to automate the manufacturing of cell therapies.

  1. Factors controlling bacteria and protists in selected Mazurian eutrophic lakes (North-Eastern Poland) during spring

    Science.gov (United States)

    2013-01-01

    Background The bottom-up (food resources) and top-down (grazing pressure) controls, with other environmental parameters (water temperature, pH) are the main factors regulating the abundance and structure of microbial communities in aquatic ecosystems. It is still not definitively decided which of the two control mechanisms is more important. The significance of bottom-up versus top-down controls may alter with lake productivity and season. In oligo- and/or mesotrophic environments, the bottom-up control is mostly important in regulating bacterial abundances, while in eutrophic systems, the top-down control may be more significant. Results The abundance of bacteria, heterotrophic (HNF) and autotrophic (ANF) nanoflagellates and ciliates, as well as bacterial production (BP) and metabolically active cells of bacteria (CTC, NuCC, EST) were studied in eutrophic lakes (Mazurian Lake District, Poland) during spring. The studied lakes were characterized by high nanoflagellate (mean 17.36 ± 8.57 × 103 cells ml-1) and ciliate abundances (mean 59.9 ± 22.4 ind. ml-1) that were higher in the euphotic zone than in the bottom waters, with relatively low bacterial densities (4.76 ± 2.08 × 106 cells ml-1) that were lower in the euphotic zone compared to the profundal zone. Oligotrichida (Rimostrombidium spp.), Prostomatida (Urotricha spp.) and Scuticociliatida (Histiobalantium bodamicum) dominated in the euphotic zone, whereas oligotrichs Tintinnidium sp. and prostomatids Urotricha spp. were most numerous in the bottom waters. Among the staining methods used to examine bacterial cellular metabolic activity, the lowest percentage of active cells was recorded with the CTC (1.5–15.4%) and EST (2.7–14.2%) assay in contrast to the NuCC (28.8–97.3%) method. Conclusions In the euphotic zone, the bottom-up factors (TP and DOC concentrations) played a more important role than top-down control (grazing by protists) in regulating bacterial numbers and activity

  2. Culture beats gender? The importance of controlling for identity- and parenting-related risk factors in adolescent psychopathology.

    Science.gov (United States)

    Seiffge-Krenke, Inge; Persike, Malte; Besevegis, Elias; Chau, Cecilia; Karaman, Neslihan Güney; Lannegrand-Willems, Lyda; Lubiewska, Katharzyna; Rohail, Iffat

    2018-02-01

    This study analyzed the unique effects of gender and culture on psychopathology in adolescents from seven countries after controlling for factors which might have contributed to variations in psychopathology. In a sample 2259 adolescents (M = 15 years; 54% female) from France, Germany, Turkey, Greece, Peru, Pakistan, and Poland identity stress, coping with identity stress, maternal parenting (support, psychological control, anxious rearing) and psychopathology (internalizing, externalizing and total symptomatology) were assessed. Due to variations in stress perception, coping style and maternal behavior, these covariates were partialed out before the psychopathology scores were subjected to analyses of variance with gender and country as factors. These analyses leveled out the main effect of country and revealed country-specific gender effects. In four countries, males reported higher internalizing and total symptomatology than females. Partialing out the covariates resulted in a clearer picture of culture-specific and gender-dependent effects on psychopathology, which is helpful in designing interventions. Copyright © 2017 The Foundation for Professionals in Services for Adolescents. Published by Elsevier Ltd. All rights reserved.

  3. Factors Influencing Prevention and Control of Malaria among ...

    African Journals Online (AJOL)

    AJRH Managing Editor

    investigate factors that influence malaria prevention and control practices among pregnant ... treatment of clinical cases and the promotion of ... influence their decision regarding malaria ..... have the ability to purchase anti-malaria drugs that.

  4. Survey of control-room design practices with respect to human factors engineering

    International Nuclear Information System (INIS)

    Seminara, J.L.; Parsons, S.O.

    1980-01-01

    Human factors engineering is an interdisciplinary speciality concerned with influencing the design of equipment systems, facilities, and operational environments to promote safe, efficient, and reliable operator performance. This emphasis has been applied to most military and space systems in the past 30 y. A review of five nuclear power-plant control rooms, reported in the November-December 1977 issue of Nuclear Safety, revealed that human factors principles of design have generally not been incorporated in present-generation control rooms. This article summarizes the findings of a survey of 20 control-board designers from a mix of nuclear steam-supply system and architect-engineering firms. The interviews with these designers probed design methods currently used in developing control rooms. From these data it was concluded that there is currently no consistent, formal, uniform concern for the human factors aspects of control-room design on the part of the design organizations, the utilities, or the Nuclear Regulatory Commission. Although all the parties involved are concerned with human factors issues, this responsibility is not focused, and human factors yardsticks, or design standards, specific to power plants have not been evolved and applied in the development and verification of control-room designs from the standpoint of the man-machine interface

  5. Dealing With A Controllable Risk Factor Like Diet In The ...

    African Journals Online (AJOL)

    Cardiovascular disease (CVD) is a silent killer in Nigeria and many parts of the world. Certain factors increase the risk of CVD. While there are controllable factors that contribute and predispose to the development of CVD like diet, exercise, tobacco use, high blood pressure and obesity, there are uncontrollable factors like ...

  6. Factors Associated with Long-Term Control of Type 2 Diabetes Mellitus.

    Science.gov (United States)

    Badedi, Mohammed; Solan, Yahiya; Darraj, Hussain; Sabai, Abdullah; Mahfouz, Mohamed; Alamodi, Saleh; Alsabaani, Abdullah

    2016-01-01

    Aims. This study assessed factors associated with glycemic control among Saudi patients with Type 2 diabetes mellitus (T2DM). Methods. We conducted an analytical cross-sectional study, which included a random sample of 288 patients with T2DM proportional to the diabetes population of each primary health care center in Jazan city, Kingdom of Saudi Arabia. Results. More than two-thirds (74%) of patients had poor glycemic control. Lack of education, polypharmacy, and duration of diabetes ≥ 7 years were significantly associated with higher glycated hemoglobin (HbA1c). Moreover, patients who were smoker or divorced were significantly more likely to have higher HbA1c. The patients who did not comply with diet or take their medications as prescribed had poor glycemic control. The study found lower HbA1c levels among patients who received family support or had close relationship with their physicians. Similarly, knowledgeable patients towards diabetes or those with greater confidence in ability to manage self-care behaviors had a lower HbA1c. In contrast, risk factors such as depression or stress were significantly correlated with poorer glycemic control. Conclusion. The majority of T2DM patients had poor glycemic control. The study identified several factors associated with glycemic control. Effective and tailored interventions are needed to mitigate exposure to these risk factors. This would improve glycemic control and reduce the risks inherent to diabetes complications.

  7. Factors Associated with Long-Term Control of Type 2 Diabetes Mellitus

    Directory of Open Access Journals (Sweden)

    Mohammed Badedi

    2016-01-01

    Full Text Available Aims. This study assessed factors associated with glycemic control among Saudi patients with Type 2 diabetes mellitus (T2DM. Methods. We conducted an analytical cross-sectional study, which included a random sample of 288 patients with T2DM proportional to the diabetes population of each primary health care center in Jazan city, Kingdom of Saudi Arabia. Results. More than two-thirds (74% of patients had poor glycemic control. Lack of education, polypharmacy, and duration of diabetes ≥ 7 years were significantly associated with higher glycated hemoglobin (HbA1c. Moreover, patients who were smoker or divorced were significantly more likely to have higher HbA1c. The patients who did not comply with diet or take their medications as prescribed had poor glycemic control. The study found lower HbA1c levels among patients who received family support or had close relationship with their physicians. Similarly, knowledgeable patients towards diabetes or those with greater confidence in ability to manage self-care behaviors had a lower HbA1c. In contrast, risk factors such as depression or stress were significantly correlated with poorer glycemic control. Conclusion. The majority of T2DM patients had poor glycemic control. The study identified several factors associated with glycemic control. Effective and tailored interventions are needed to mitigate exposure to these risk factors. This would improve glycemic control and reduce the risks inherent to diabetes complications.

  8. Study on quality control measures of static casting main pipe in PWR nuclear power plant

    International Nuclear Information System (INIS)

    Jiang Zhenbiao; Li Guanying; Liu Zhicheng

    2013-01-01

    This study analyzes the main reasons which impact the quality of primary pipe static casting elbows in PWR-M310 nuclear power plant. The quality control measures are developed from the election and inspection of material, improving sand production and casting process, improving lean management of personnel. The static casting defects of primary pipe elbows for Fuqing Unit 1 and 2 were down to less than 50% of the former project. The quality of static casting for the primary pipe elbows was significantly improved. Moreover, the implementation saves human resources and financing to repair casting defects, and also helps to win the delivery schedule. The quality control measures are good reference for improving primary pipe casting process. This study provides valuable experience for further study of improving the quality of static casting for the primary pipe of PWR nuclear power plant. (authors)

  9. On frequency-weighted coprime factorization based controller reduction

    OpenAIRE

    Varga, Andras

    2003-01-01

    We consider the efficient solution of a class of coprime factorization based controller approximation problems by using frequency-weighted balancing related model reduction approaches. It is shown that for some special stability enforcing frequency-weights, the computation of the frequency-weighted controllability and observability grammians can be done by solving reduced order Lyapunov equations. The new approach can be used in conjunction with accuracy enhancing square-root and balancing-fr...

  10. Look into the PS Main Control Room (partial view)

    CERN Multimedia

    1974-01-01

    Jean-Pierre Potier at work. The 26 GeV Synchrotron and later also its related machines (Linacs 1,2,3; PS-Booster, LEP-Injector Linacs and Electron-Positron Accumulator; Antiproton Accumulator, Antiproton Collector, Low Energy Antiproton Ring and more recently Antiproton Decelerator) were all controlled from the PS control room situated at the Meyrin site. The SPS and LEP were controlled from a separat control centre on the Prevessin site. In 2005 all controls were transferred to the Prevessin centre.

  11. EVALUATION OF FOUR INTEGRATED PEST MANAGEMENT PACKAGES FOR CONTROLLING MAIN PESTS OF COTTON IN RAINFED FIELDS

    OpenAIRE

    Nurindah Nurindah; Dwi Adi Sunarto

    2014-01-01

    Cotton production nationally is low due to various constraints, including pests. Two main pests commonly found in cotton plantation in rain fed fields are cotton leafhopper (Amrasca biguttula) and cotton bollworm (Helicoverpa armigera). The study aimed to evaluate four packages of integrated pest management (IPM) techniques to control cotton leafhopper and cotton bollworm in rain fed fields. The experiment was conducted in farmers’ fields at Asembagus, East Java, between January and July 2012...

  12. Risk factors for posterior vitreous detachment: a case-control study.

    Science.gov (United States)

    Chuo, Jean Y; Lee, Tracy Y Y; Hollands, Hussein; Morris, Andrew H; Reyes, Romina C; Rossiter, Jonathan D; Meredith, Sarah P; Maberley, David A L

    2006-12-01

    To identify possible risk factors for the development of posterior vitreous detachment (PVD). Retrospective case-control study. A total of 138 cases with PVD and 114 age-matched controls were accrued from two different sites. Demographic, medical, ocular, and lifestyle data were obtained through chart review, questionnaires, and clinical examination. A 108-item semiquantitative food frequency questionnaire was also used to estimate macro- and micronutrient intake. Univariate and multivariate regression analyses were employed to identify variables significantly associated with the main outcome measure of PVD. Subgroup analysis of gender-specific variables was performed. Among all patients, multivariate regression analysis demonstrated female gender (odds ratio [OR] = 2.01, P = .016), myopic refraction (OR = 4.32, P < .0005), and higher intake of vitamin B6 (OR = 2.61, P = .001) to be associated with PVD after controlling for age. In the subgroup analysis of women, menopause (OR = 18.2, P < .0005), myopic refraction (OR = 3.42, P = .01), and higher intake of vitamin B6 (OR = 3.92, P = .005) were associated with PVD. Specifically, there was a significant association between vitamin B6 and PVD amongst premenopausal women but not amongst postmenopausal women. An association between PVD and menopause has not been documented previously. We suspect that high estrogen levels seen in premenopausal women may be protective against PVD and that hormonal changes associated with menopause may lead to changes in the vitreous, predisposing to PVD. Higher levels of intake of vitamin B6 were also associated with the development of PVD in premenopausal women possibly through an anti-estrogen effect. These findings should be investigated further with prospective studies.

  13. Factors controlling accumulation of soil organic carbon along vegetation succession in a typical karst region in Southwest China

    Energy Technology Data Exchange (ETDEWEB)

    Liu, Shujuan [Key Laboratory of Agro-ecological Processes in Subtropical Region, Institute of Subtropical Agriculture, Chinese Academy of Sciences, Changsha 410125 (China); Huanjiang Observation and Research Station of Karst Ecosystem, Chinese Academy of Sciences, Huanjiang, Guangxi Zhuang Autonomous Region 547100 (China); University of Chinese Academy of Sciences, Beijing 100049 (China); Zhang, Wei [Key Laboratory of Agro-ecological Processes in Subtropical Region, Institute of Subtropical Agriculture, Chinese Academy of Sciences, Changsha 410125 (China); Huanjiang Observation and Research Station of Karst Ecosystem, Chinese Academy of Sciences, Huanjiang, Guangxi Zhuang Autonomous Region 547100 (China); Wang, Kelin, E-mail: kelin@isa.ac.cn [Key Laboratory of Agro-ecological Processes in Subtropical Region, Institute of Subtropical Agriculture, Chinese Academy of Sciences, Changsha 410125 (China); Huanjiang Observation and Research Station of Karst Ecosystem, Chinese Academy of Sciences, Huanjiang, Guangxi Zhuang Autonomous Region 547100 (China); Pan, Fujing [Key Laboratory of Agro-ecological Processes in Subtropical Region, Institute of Subtropical Agriculture, Chinese Academy of Sciences, Changsha 410125 (China); Huanjiang Observation and Research Station of Karst Ecosystem, Chinese Academy of Sciences, Huanjiang, Guangxi Zhuang Autonomous Region 547100 (China); University of Chinese Academy of Sciences, Beijing 100049 (China); Yang, Shan [Changsha university, Changsha 410003 (China); Shu, Shiyan [Changjiang Project Supervision & Consultancy Co. Ltd, Wuhan 430010 (China); Changjiang Ecology (Hubei) Technology Development LLC, Wuhan 430010 (China)

    2015-07-15

    Vegetation succession enhances the accumulation of carbon in the soil. However, little is known about the mechanisms underlying soil organic carbon (SOC) accumulation in different vegetation types in the karst region of Southwest China. The goal of this study was to identify and prioritize the effects of environmental parameters, including soil physico-chemical properties, microbial biomass, enzyme activities, and litter characteristics, on SOC accumulation along a vegetation succession sere (grassland, shrubland, secondary forest, and primary forest) in the karst landscape of Southwest China. Relationships between these parameters and SOC were evaluated by redundancy analysis. The results showed that SOC accumulation was significantly different among vegetation types (P < 0.01) and increased with vegetation succession (from 29.10 g·kg{sup −1} in grassland to 73.92 g·kg{sup −1} in primary forest). Soil biochemistry and physical characteristics significantly affected the accumulation of SOC. Soil microbial biomass showed a predominant effect on SOC in each of the four vegetation types. In addition, the soil physical property (especially the silt content) was another controlling factor in the early stages (grassland), and urease activity and saccharase activity were important controlling factors in the early-middle and middle-late stages, respectively. Litter characteristics only showed mild effects on SOC accumulation. Variation partitioning analysis showed that the contribution of sole main factors to SOC variation decreased, while the interaction effect among parameters increased along the succession gradient. - Highlights: • Vegetation restoration is conducive to soil carbon sequestration in karst areas. • The factors controlling SOC accumulation differed along vegetation succession. • The interaction effect among significant factors became more and more prominent along succession.

  14. Mitochondrial respiratory control is lost during growth factor deprivation.

    Science.gov (United States)

    Gottlieb, Eyal; Armour, Sean M; Thompson, Craig B

    2002-10-01

    The ability of cells to maintain a bioenergetically favorable ATP/ADP ratio confers a tight balance between cellular events that consume ATP and the rate of ATP production. However, after growth factor withdrawal, the cellular ATP/ADP ratio declines. To investigate these changes, mitochondria from growth factor-deprived cells isolated before the onset of apoptosis were characterized in vitro. Mitochondria from growth factor-deprived cells have lost their ability to undergo matrix condensation in response to ADP, which is accompanied by a failure to perform ADP-coupled respiration. At the time of analysis, mitochondria from growth factor-deprived cells were not depleted of cytochrome c and cytochrome c-dependent respiration was unaffected, demonstrating that the inhibition of the respiratory rate is not due to loss of cytochrome c. Agents that disrupt the mitochondrial outer membrane, such as digitonin, or maintain outer membrane exchange of adenine nucleotide, such as Bcl-x(L), restored ADP-dependent control of mitochondrial respiration. Together, these data suggest that the regulation of mitochondrial outer membrane permeability contributes to respiratory control.

  15. Human Factors Analysis of Pipeline Monitoring and Control Operations: Final Technical Report

    Science.gov (United States)

    2008-11-26

    The purpose of the Human Factors Analysis of Pipeline Monitoring and Control Operations project was to develop procedures that could be used by liquid pipeline operators to assess and manage the human factors risks in their control rooms that may adv...

  16. [Preliminary study on main impacting factors on brand equity of listed traditional Chinese medicine companies].

    Science.gov (United States)

    Tan, Wei; Geng, Dong-Mei; Rong, Xue; Li, Zi; Liu, Wei; Yang, Li; Xu, Si-Qun; Jie, Xiao-Qian

    2013-05-01

    The brand equity is valuable intangible assets of traditional Chinese medicine companies, who are excellent representatives of traditional Chinese medicine enterprises and the most promising ones to good international medicine brands. However, there is still no systematic study on how to correctly evaluate the brand equity of listed traditional Chinese medicine companies at present. To make it clear, the main impacting factors on brand equity of listed traditional Chinese medicine companies, both structured open outline pre-research and closed questionnaire research were adopted for the field survey, and some suggestions for how to protect and enhance the brand equity were also presented on the basis of survey and analysis, in the hope of improving the brand management level of listed traditional Chinese medicine companies, and making a beneficial exploration for the development of brand theory of the traditional Chinese medicine industry.

  17. Environmental and hormonal factors controlling reversible colour change in crab spiders.

    Science.gov (United States)

    Llandres, Ana L; Figon, Florent; Christidès, Jean-Philippe; Mandon, Nicole; Casas, Jérôme

    2013-10-15

    Habitat heterogeneity that occurs within an individual's lifetime may favour the evolution of reversible plasticity. Colour reversibility has many different functions in animals, such as thermoregulation, crypsis through background matching and social interactions. However, the mechanisms underlying reversible colour changes are yet to be thoroughly investigated. This study aims to determine the environmental and hormonal factors underlying morphological colour changes in Thomisus onustus crab spiders and the biochemical metabolites produced during these changes. We quantified the dynamics of colour changes over time: spiders were kept in yellow and white containers under natural light conditions and their colour was measured over 15 days using a spectrophotometer. We also characterised the chemical metabolites of spiders changing to a yellow colour using HPLC. Hormonal control of colour change was investigated by injecting 20-hydroxyecdysone (20E) into spiders. We found that background colouration was a major environmental factor responsible for colour change in crab spiders: individuals presented with white and yellow backgrounds changed to white and yellow colours, respectively. An ommochrome precursor, 3-OH-kynurenine, was the main pigment responsible for yellow colour. Spiders injected with 20E displayed a similar rate of change towards yellow colouration as spiders kept in yellow containers and exposed to natural sunlight. This study demonstrates novel hormonal manipulations that are capable of inducing reversible colour change.

  18. Balance, Falls-Related Self-Efficacy, and Psychological Factors amongst Older Women with Chronic Low Back Pain: A Preliminary Case-Control Study

    OpenAIRE

    Champagne, Annick; Prince, François; Bouffard, Vicky; Lafond, Danik

    2012-01-01

    Objective. To investigate balance functions in older women and evaluate the association of the fear-avoidance beliefs model (FABM) factors with balance and mobility performance. Participants. Fifteen older women with CLBP was compared with age-matched pain-free controls (n = 15). Main Outcome Measures. Pain intensity, falls-related self-efficacy and intrinsic constructs in the FABM were evaluated. Postural steadiness (centre of pressure (COP)) and mobility functions were assessed. Linear rela...

  19. 75 FR 69912 - Pipeline Safety: Control Room Management/Human Factors

    Science.gov (United States)

    2010-11-16

    ... 192 and 195 [Docket ID PHMSA-2007-27954] RIN 2137-AE64 Pipeline Safety: Control Room Management/Human... Control Room Management/Human Factors rule at 49 CFR 192.631 and 195.446. The NPRM proposes to expedite... rule and to engage in open discussions with the agency at PHMSA's Control Room Management...

  20. 3D microwave cavity with magnetic flux control and enhanced quality factor

    Energy Technology Data Exchange (ETDEWEB)

    Reshitnyk, Yarema [The University of Queensland, School of Mathematics and Physics, St Lucia (Australia); Jerger, Markus [The University of Queensland, ARC Centre of Excellence for Engineered Quantum Systems, 4072 (Australia); Fedorov, Arkady [The University of Queensland, School of Mathematics and Physics, St Lucia (Australia); The University of Queensland, ARC Centre of Excellence for Engineered Quantum Systems, 4072 (Australia)

    2016-12-15

    Three-dimensional (3D) microwave cavities have been extensively used for coupling and interacting with superconducting quantum bits (qubits), providing a versatile platform for quantum control experiments and for realizing hybrid quantum systems. While having high quality factors (>10{sup 6}) superconducting cavities do not permit magnetic field control of qubits. In contrast, cavities made of normal metals are transparent to magnetic fields, but experience lower quality factors (∝10{sup 4}). We have created a hybrid cavity which is primarily composed of aluminium but also contains a small copper insert reaching the internal quality factor of ≅10{sup 5}, an order of magnitude improvement over all previously tested normal metal cavities. In order to demonstrate precise magnetic control, we performed spectroscopy of three superconducting qubits, where individual control of each qubit's frequency was exerted with small external wire coils. An improvement in quality factor and magnetic field control makes this 3D hybrid cavity an attractive new element for circuit quantum electrodynamics experiments. (orig.)

  1. [Growth characteristics of Porites lutea skeleton in east sea area of Hainan Island, China and main affecting environmental factors.

    Science.gov (United States)

    Jiang, Qiao Wen; Cao, Zhi Min; Wang, Dao Ru; Li, Yuan Chao; Ni, Jian Yu

    2016-03-01

    The growth characteristics of Porites lutea skeleton in east sea area of Hainan Island were studied by CoralXDS software based on X-ray chronology. The growth parameters obtained included extension rate (ER), skeleton density (D), and calcification rate (CR). The results showed that ER varied from 0.49 to 1.10 cm·a -1 with an annual average of 0.76 cm·a -1 , D varied from 1.11 to 1.35 g·cm -3 with an annual average of 1.22 g·cm -3 , and CR varied from 0.55 to 1.41 g·cm -2 ·a -1 with an annual average of 0.94 g·cm -2 ·a -1 . Statistical analyses indicated that sea surface temperature (SST) was the key environmental factor that controlled the growth characteristics, as it highly co-varied with ER and CR, less so with D. All of the three growth characteristics increased with the increase of SST. There were other factors that influenced the growth characteristics of the coral column, such as light, water salinity, and hydrodynamics, etc. In addition, typhoon and severe tropical storms also imposed a significant impact on the growth pattern of Porites lutea coral. The change in growth pattern of coral skeleton in east of Hainan Island was a response to complex climate fluctuation. Over the past century, SST of east Hainan Island dramatically increased at a rate of 0.15 ℃·(10 a) -1 . The SST increase trend for the oceanic region could be divided into two stages, early 1940s and early 1980s. The human activities and global warming was the main causes for the increase of SST.

  2. Analysis and Control of Buck-Boost Converter with the Same Input Polarity Based on Novel Energy Factor Evaluation

    Directory of Open Access Journals (Sweden)

    Mahmoud Shaker Nasr

    2017-03-01

    Full Text Available This paper presents firstly a buck-boost circuit with the advantage that its output voltage polarity is the same as the input polarity. The circuit operation is presented and analyzed in different modes of operation. The well known parameters used in evaluation of DC/DC converters like Total Harmonic Distortion THD, Power Factor PF, and Ripple Factor RF have no meaning in DC/DC converters, so it is to introduce efficient concepts to permit a fair evaluation of the converter. This paper present other parameters that can be used to study the characteristics of the converter and gives a real and logic means of its operation. These main parameters are: pumping energy PE, storage energy SE, energy factor EF, and energy losses EL. In addition, the converter efficiency is not considered as 100 % as taken in most analyzing studies. The positive DC/DC buck-boost converter is evaluated according to the new concepts and the system model is deduced for different cases of operation taking into account the resistance of the circuit inductor. The circuit is implemented practically and the presented obtained results show the correct operation under different modes of operation. In addition the control design of the converter is built such that a PI controller with windup is considered. In order to test the effectiveness of the designed control algorithm, the system were exposed to different voltage reference values and the obtained results demonstrate that the system responses for all cases are very acceptable according to the criteria of the control system theory.

  3. Erectile Dysfunction Among HIV Patients Undergoing Highly Active Antiretroviral Therapy: Dyslipidemia as a Main Risk Factor

    Science.gov (United States)

    Romero-Velez, Gustavo; Lisker-Cervantes, Andrés; Villeda-Sandoval, Christian I; Sotomayor de Zavaleta, Mariano; Olvera-Posada, Daniel; Sierra-Madero, Juan Gerardo; Arreguin-Camacho, Lucrecia O; Castillejos-Molina, Ricardo A

    2014-01-01

    Objective To assess the prevalence and risk factors of erectile dysfunction (ED) in HIV patients from the HIV clinic of a tertiary referral center in Mexico City. Design Prevalence was obtained from cross-sectional studies, and the International Index of Erectile Function (IIEF), a standardized method, was used to assess ED. Methods A cross-sectional study was performed in the HIV clinic. Participants completed the IIEF to allow ED assessment. Information on demographics, clinical and HIV-related variables was retrieved from their medical records. Results One hundred and nine patients were included, with a mean age of 39.9 ± 8.8 years. ED was present in 65.1% of the individuals. Patients had been diagnosed with HIV for a mean of 92.7 ± 70.3 months and had undergone a mean 56.4 ± 45.5 months of HAART. The only variable associated with ED in the univariate analysis was dyslipidemia, and this association was also found in the multivariate analysis (P = 0.01). Conclusions ED is highly prevalent in HIV patients. Dyslipidemia should be considered as a risk factor for ED in HIV patients. Romero-Velez G, Lisker-Cervantes A, Villeda-Sandoval CI, Sotomayor de Zavaleta M, Olvera-Posada D, Sierra-Madero JG, Arreguin-Camacho LO, and Castillejos-Molina RA. Erectile dysfunction among HIV patients undergoing highly active antiretroviral therapy: Dyslipidemia as a main risk factor. Sex Med 2014;2:24–30. PMID:25356298

  4. Factors controlling pathogen destruction during anaerobic digestion of biowastes

    International Nuclear Information System (INIS)

    Smith, S.R.; Lang, N.L.; Cheung, K.H.M.; Spanoudaki, K.

    2005-01-01

    Anaerobic digestion is the principal method of stabilising biosolids from urban wastewater treatment in the UK, and it also has application for the treatment of other types of biowaste. Increasing awareness of the potential risks to human and animal health from environmental sources of pathogens has focused attention on the efficacy of waste treatment processes at destroying pathogenic microorganisms in biowastes recycled to agricultural land. The degree of disinfection achieved by a particular anaerobic digester is influenced by a variety of interacting operational variables and conditions, which can often deviate from the ideal. Experimental investigations demonstrate that Escherichia coli and Salmonella spp. are not damaged by mesophilic temperatures, whereas rapid inactivation occurs by thermophilic digestion. A hydraulic, biokinetic and thermodynamic model of pathogen inactivation during anaerobic digestion showed that a 2 log 10 reduction in E. coli (the minimum removal required for agricultural use of conventionally treated biosolids) is likely to challenge most conventional mesophilic digesters, unless strict maintenance and management practices are adopted to minimise dead zones and by-pass flow. Efficient mixing and organic matter stabilisation are the main factors controlling the rate of inactivation under mesophilic conditions and not a direct effect of temperature per se on pathogenic organisms

  5. Performance ratings and personality factors in radar controllers.

    Science.gov (United States)

    1970-09-01

    The purpose of the study was to determine whether primary or second-order personality questionnaire factors were related to job performance ratings on the Employee Appraisal Record in a sample of 264 radar controllers. A Pearson correlation matrix wa...

  6. Research on transfer rule of the monitoring of operator in digital main control room of nuclear power plant

    International Nuclear Information System (INIS)

    Zhang Li; Li Linfeng; Li Pengcheng; Lu Changshen; Huang Weigang; Dai Zhonghua; Huang Yuanzheng; Chen Qingqing

    2013-01-01

    In the digital main control room of nuclear power plants, monitoring the operating status of the system of reactor is not only one of the most important tasks of the operators, but also the basis and premise of controlling the system of reactor running correctly. After analyzing, inducing, summarizing the data obtained, we found the operators' monitor behavior could be classified as procedure transfer, abnormal transfer, and exchange transfer. The times of exchange transfer is 29% of the total transfer times, abnormal transfer is 14%, regulation transfer is 36%, and others are 21%. (authors)

  7. Parasitism as the main factor shaping peptide vocabularies in current organisms.

    Science.gov (United States)

    Zemková, Michaela; Zahradník, Daniel; Mokrejš, Martin; Flegr, Jaroslav

    2017-06-01

    Self/non-self-discrimination by vertebrate immune systems is based on the recognition of the presence of peptides in proteins of a parasite that are not contained in the proteins of a host. Therefore, a reduction of the number of 'words' in its own peptide vocabulary could be an efficient evolutionary strategy of parasites for escaping recognition. Here, we compared peptide vocabularies of 30 endoparasitic and 17 free-living unicellular organisms and also eight multicellular parasitic and 16 multicellular free-living organisms. We found that both unicellular and multicellular parasites used a significantly lower number of different pentapeptides than free-living controls. Impoverished pentapeptide vocabularies in parasites were observed across all five clades that contain both the parasitic and free-living species. The effect of parasitism on a number of peptides used in an organism's proteins is larger than effects of all other studied factors, including the size of a proteome, the number of encoded proteins, etc. This decrease of pentapeptide diversity was partly compensated for by an increased number of hexapeptides. Our results support the hypothesis of parasitism-associated reduction of peptide vocabulary and suggest that T-cell receptors mostly recognize the five amino acids-long part of peptides that are presented in the groove of major histocompatibility complex molecules.

  8. Plate convergence, crustal delamination, extrusion tectonics and minimization of shortening work as main controlling factors of the recent Mediterranean deformation pattern

    Directory of Open Access Journals (Sweden)

    D. Babbucci

    1997-06-01

    Full Text Available It is argued that the time-space distribution of major post middle Miocene deformation events in the Central-Eastern Mediterranean region, deduced from the relevant literature, can be coherently explained as a consequence of the convergence between the Africa/Arabia and Eurasia blocks. This plate convergence has mainly been accommodated by the consumption of the thinnest parts of the Northern African (Ionian and Levantine basins and peri-Adriatic margins. During each evolutionary phase the space distribution of trench zones is controlled by the basic physical requirement of minimizing the work of horizontal forces, induced by plate convergence, against the resisting forces, i.e., the cohesion of the upper brittle crustal layer and the buoyancy forces at the consuming boundaries. The significant changes of tectonic styles which determined the transition from one phase to the next, like those which occurred around the Messinian and the late Pliocene-early Pleistocene, were determined by the suture of consuming boundaries. When such an event occurs, the system must activate alternative consuming processes to accommodate the convergence of the major confining blocks. The observed deformations in the study area suggest that this tectonic reorganization mostly developed by the lateral extrusion of crustal wedges away from the sutured borders. This mechanism allowed the translation of maximum horizontal stresses from the locked collisional fronts to the zones where consumable lithosphere was still present, in order to activate the next consuming processes. The extensional episodes which led to the formation of basins and troughs in the Tyrrhenian and Aegean zones are interpreted as secondary effects of the outward escape of crustal wedges, like those which occurred in response to longitudinal compressional regimes in the Apennines and Aegean regions.

  9. HIV Infection Is Not Associated With Aortic Stiffness. Traditional Cardiovascular Risk Factors Are the Main Determinants-Cross-sectional Results of INI-ELSA-BRASIL.

    Science.gov (United States)

    Moreira, Rodrigo C; Mill, José G; Grinsztejn, Beatriz; Veloso, Valdilea; Fonseca, Maria de Jesus; Griep, Rosane H; Bensenor, Isabela; Cardoso, Sandra W; Lotufo, Paulo; Chor, Dora; Pacheco, Antonio G

    2018-05-01

    Aortic stiffness measured by carotid-femoral pulse wave velocity (cf-PWV) is a marker of subclinical atherosclerosis. We propose to assess whether HIV infection is associated with arterial stiffness and their determinants in HIV-infected subjects. We compared data from an HIV cohort (644 patients, HIV+) in Rio de Janeiro with 2 groups: 105 HIV-negative (HIV-) individuals and 14,873 participants of the ELSA-Brasil study. We used multivariable linear regression to investigate factors associated with cf-PWV and whether HIV was independently associated with aortic stiffness and propensity score weighting to control for imbalances between groups. From 15,860 participants, cf-PWV was obtained in 15,622 (98.5%). Median age was 51 (interquartile range 45-58), 44.41 (35.73, 54.72), and 43.60 (36.01, 50.79) years (P ELSA-Brasil, HIV- and HIV+, respectively (P ELSA-Brasil [β = -0.05; 95% confidence interval (CI) = -0.23; P = 0.12; P = 0.52] or with the HIV- groups (β = 0.10; 95% CI = -0.10; 0, 31; P = 0.32). Traditional risk factors were associated with higher cf-PWV levels in the HIV+ group, particularly waist-to-hip ratio (β = 0.20; 95% CI = 0.10; 0.30; P < 0.001, result per one SD change). HIV infection was not associated with higher aortic stiffness according to our study. In HIV-infected subjects, the stiffness of large arteries is mainly associated with traditional risk factors and not to the HIV infection per se.

  10. The transcription factor Prep1 controls hepatic insulin sensitivity and gluconeogenesis by targeting nuclear localization of FOXO1

    International Nuclear Information System (INIS)

    Kulebyakin, Konstantin; Penkov, Dmitry; Blasi, Francesco; Akopyan, Zhanna; Tkachuk, Vsevolod

    2016-01-01

    Liver plays a key role in controlling body carbohydrate homeostasis by switching between accumulation and production of glucose and this way maintaining constant level of glucose in blood. Increased blood glucose level triggers release of insulin from pancreatic β-cells. Insulin represses hepatic glucose production and increases glucose accumulation. Insulin resistance is the main cause of type 2 diabetes and hyperglycemia. Currently thiazolidinediones (TZDs) targeting transcriptional factor PPARγ are used as insulin sensitizers for treating patients with type 2 diabetes. However, TZDs are reported to be associated with cardiovascular and liver problems and stimulate obesity. Thus, it is necessary to search new approaches to improve insulin sensitivity. A promising candidate is transcriptional factor Prep1, as it was shown earlier it could affect insulin sensitivity in variety of insulin-sensitive tissues. The aim of the present study was to evaluate a possible involvement of transcriptional factor Prep1 in control of hepatic glucose accumulation and production. We created mice with liver-specific Prep1 knockout and discovered that hepatocytes derived from these mice are much more sensitive to insulin, comparing to their WT littermates. Incubation of these cells with 100 nM insulin results in almost complete inhibition of gluconeogenesis, while in WT cells this repression is only partial. However, Prep1 doesn't affect gluconeogenesis in the absence of insulin. Also, we observed that nuclear content of gluconeogenic transcription factor FOXO1 was greatly reduced in Prep1 knockout hepatocytes. These findings suggest that Prep1 may control hepatic insulin sensitivity by targeting FOXO1 nuclear stability. - Highlights: • A novel model of liver-specific Prep1 knockout is established. • Ablation of Prep1 in hepatocytes increases insulin sensitivity. • Prep1 controls hepatic insulin sensitivity by regulating localization of FOXO1. • Prep1 regulates

  11. Risk factors for maternal mortality in the west of Iran: a nested case-control study

    Directory of Open Access Journals (Sweden)

    Jalal Poorolajal

    2014-11-01

    Full Text Available OBJECTIVES: With a gradual decline in maternal mortality in recent years in Iran, this study was conducted to identify the remaining risk factors for maternal death. METHODS: This 8-year nested case-control study was conducted in Hamadan Province, in the west of Iran, from April 2006 to March 2014. It included 185 women (37 cases and 148 controls. All maternal deaths that occurred during the study period were considered cases. For every case, four women with a live birth were selected as controls from the same area and date. Conditional logistic regression analysis was performed and the odds ratio (OR and its 95% confidence interval (CI were obtained for each risk factor. RESULTS: The majority of cases were aged 20-34 years, died in hospital, and lived in urban areas. The most common causes of death were bleeding, systemic disease, infection, and pre-eclampsia. The OR estimate of maternal death was 8.48 (95% CI=1.26-56.99 for advanced maternal age (≥35 years; 2.10 (95% CI=0.07-65.43 for underweight and 10.99 (95% CI=1.65-73.22 for overweight or obese women compared to those with normal weight; 1.56 (95% CI=1.08-2.25 for every unit increase in gravidity compared to those with one gravidity; 1.73 (95% CI=0.34-8.88 for preterm labors compared to term labors; and 17.54 (95% CI= 2.71-113.42 for women with systemic diseases. CONCLUSIONS: According to our results, advanced maternal age, abnormal body mass index, multiple gravidity, preterm labor, and systemic disease were the main risk factors for maternal death. However, more evidence based on large cohort studies in different settings is required to confirm our results.

  12. Tobacco control policy development in the European Union: do political factors matter?

    NARCIS (Netherlands)

    Bosdriesz, Jizzo R.; Willemsen, Marc C.; Stronks, Karien; Kunst, Anton E.

    2015-01-01

    There has been much variation between European countries in the development of tobacco control policy. Not much is known about the factors that shape this variation. This study aimed to assess the role of political factors in tobacco control policy development. We used data from 11 European

  13. Risk factors for Creutzfeldt-Jakob disease: a reanalysis of case-control studies.

    NARCIS (Netherlands)

    D.P.W.M. Wientjens (Dorothee); Z. Davanipour; K. Kondo; W.B. Matthews; R.G. Will (Robert); C.M. van Duijn (Cornelia); A. Hofman (Albert)

    1996-01-01

    textabstractTo review the evidence for risk factors of Creutzfeldt-Jakob disease (CJD), we pooled and reanalyzed the raw data of three case-control studies. The pooled data set comprised 178 patients and 333 control subjects. The strength of association between CJD and putative risk factors was

  14. Quality of Life after Young Ischemic Stroke of Mild Severity Is Mainly Influenced by Psychological Factors.

    Science.gov (United States)

    de Bruijn, Marienke A A M; Synhaeve, Nathalie E; van Rijsbergen, Mariëlle W A; de Leeuw, Frank-Erik; Mark, Ruth E; Jansen, Ben P W; de Kort, Paul L M

    2015-10-01

    Long-term prognosis in terms of quality of life (QoL) in young stroke patients is of importance because they usually have a long life expectancy and extensive daily life demands. We aimed at determining which medical and psychological factors influence the QoL in young stroke patients (Young ischemic stroke patients admitted to the St. Elisabeth Hospital and the TweeSteden Hospital, Tilburg, the Netherlands, between 2000 and 2010 were included. One hundred seventy patients and 61 controls filled out the following questionnaires: (1) the Hospital Anxiety and Depression Scale, (2) the Fatigue Assessment Scale, and (3) the shortened World Health Organization Quality of Life scale. Using linear multiple regression analysis, we assessed the factors influencing QoL. QoL did not differ significantly between patients (median modified Rankin Scale score at follow-up, 0) and controls after a mean follow-up of 4.5 (standard deviation, 2.8) years. The presence of excessive fatigue was associated with lower scores on all domains of the QoL (P ≤ .003), but not for general health domain (P = .010). Similarly, depression was associated with worse QoL on the physical (P = .004) and psychological (P = .001) domains and anxiety with lower scores on the psychological (P stroke-specific factors and QoL. Fatigue and to a lesser extent depression and anxiety affect the QoL in young adults after ischemic stroke of mild severity. Therefore, young stroke patients should be informed about, screened, and, if possible, treated for fatigue, depression, and anxiety. Copyright © 2015 National Stroke Association. Published by Elsevier Inc. All rights reserved.

  15. Daughter-specific transcription factors regulate cell size control in budding yeast.

    Science.gov (United States)

    Di Talia, Stefano; Wang, Hongyin; Skotheim, Jan M; Rosebrock, Adam P; Futcher, Bruce; Cross, Frederick R

    2009-10-01

    In budding yeast, asymmetric cell division yields a larger mother and a smaller daughter cell, which transcribe different genes due to the daughter-specific transcription factors Ace2 and Ash1. Cell size control at the Start checkpoint has long been considered to be a main regulator of the length of the G1 phase of the cell cycle, resulting in longer G1 in the smaller daughter cells. Our recent data confirmed this concept using quantitative time-lapse microscopy. However, it has been proposed that daughter-specific, Ace2-dependent repression of expression of the G1 cyclin CLN3 had a dominant role in delaying daughters in G1. We wanted to reconcile these two divergent perspectives on the origin of long daughter G1 times. We quantified size control using single-cell time-lapse imaging of fluorescently labeled budding yeast, in the presence or absence of the daughter-specific transcriptional regulators Ace2 and Ash1. Ace2 and Ash1 are not required for efficient size control, but they shift the domain of efficient size control to larger cell size, thus increasing cell size requirement for Start in daughters. Microarray and chromatin immunoprecipitation experiments show that Ace2 and Ash1 are direct transcriptional regulators of the G1 cyclin gene CLN3. Quantification of cell size control in cells expressing titrated levels of Cln3 from ectopic promoters, and from cells with mutated Ace2 and Ash1 sites in the CLN3 promoter, showed that regulation of CLN3 expression by Ace2 and Ash1 can account for the differential regulation of Start in response to cell size in mothers and daughters. We show how daughter-specific transcriptional programs can interact with intrinsic cell size control to differentially regulate Start in mother and daughter cells. This work demonstrates mechanistically how asymmetric localization of cell fate determinants results in cell-type-specific regulation of the cell cycle.

  16. Daughter-Specific Transcription Factors Regulate Cell Size Control in Budding Yeast

    Science.gov (United States)

    Di Talia, Stefano; Wang, Hongyin; Skotheim, Jan M.; Rosebrock, Adam P.; Futcher, Bruce; Cross, Frederick R.

    2009-01-01

    In budding yeast, asymmetric cell division yields a larger mother and a smaller daughter cell, which transcribe different genes due to the daughter-specific transcription factors Ace2 and Ash1. Cell size control at the Start checkpoint has long been considered to be a main regulator of the length of the G1 phase of the cell cycle, resulting in longer G1 in the smaller daughter cells. Our recent data confirmed this concept using quantitative time-lapse microscopy. However, it has been proposed that daughter-specific, Ace2-dependent repression of expression of the G1 cyclin CLN3 had a dominant role in delaying daughters in G1. We wanted to reconcile these two divergent perspectives on the origin of long daughter G1 times. We quantified size control using single-cell time-lapse imaging of fluorescently labeled budding yeast, in the presence or absence of the daughter-specific transcriptional regulators Ace2 and Ash1. Ace2 and Ash1 are not required for efficient size control, but they shift the domain of efficient size control to larger cell size, thus increasing cell size requirement for Start in daughters. Microarray and chromatin immunoprecipitation experiments show that Ace2 and Ash1 are direct transcriptional regulators of the G1 cyclin gene CLN3. Quantification of cell size control in cells expressing titrated levels of Cln3 from ectopic promoters, and from cells with mutated Ace2 and Ash1 sites in the CLN3 promoter, showed that regulation of CLN3 expression by Ace2 and Ash1 can account for the differential regulation of Start in response to cell size in mothers and daughters. We show how daughter-specific transcriptional programs can interact with intrinsic cell size control to differentially regulate Start in mother and daughter cells. This work demonstrates mechanistically how asymmetric localization of cell fate determinants results in cell-type-specific regulation of the cell cycle. PMID:19841732

  17. Daughter-specific transcription factors regulate cell size control in budding yeast.

    Directory of Open Access Journals (Sweden)

    Stefano Di Talia

    2009-10-01

    Full Text Available In budding yeast, asymmetric cell division yields a larger mother and a smaller daughter cell, which transcribe different genes due to the daughter-specific transcription factors Ace2 and Ash1. Cell size control at the Start checkpoint has long been considered to be a main regulator of the length of the G1 phase of the cell cycle, resulting in longer G1 in the smaller daughter cells. Our recent data confirmed this concept using quantitative time-lapse microscopy. However, it has been proposed that daughter-specific, Ace2-dependent repression of expression of the G1 cyclin CLN3 had a dominant role in delaying daughters in G1. We wanted to reconcile these two divergent perspectives on the origin of long daughter G1 times. We quantified size control using single-cell time-lapse imaging of fluorescently labeled budding yeast, in the presence or absence of the daughter-specific transcriptional regulators Ace2 and Ash1. Ace2 and Ash1 are not required for efficient size control, but they shift the domain of efficient size control to larger cell size, thus increasing cell size requirement for Start in daughters. Microarray and chromatin immunoprecipitation experiments show that Ace2 and Ash1 are direct transcriptional regulators of the G1 cyclin gene CLN3. Quantification of cell size control in cells expressing titrated levels of Cln3 from ectopic promoters, and from cells with mutated Ace2 and Ash1 sites in the CLN3 promoter, showed that regulation of CLN3 expression by Ace2 and Ash1 can account for the differential regulation of Start in response to cell size in mothers and daughters. We show how daughter-specific transcriptional programs can interact with intrinsic cell size control to differentially regulate Start in mother and daughter cells. This work demonstrates mechanistically how asymmetric localization of cell fate determinants results in cell-type-specific regulation of the cell cycle.

  18. Antepartum risk factors for newborn encephalopathy: the Western Australian case-control study

    Science.gov (United States)

    Badawi, Nadia; Kurinczuk, Jennifer J; Keogh, John M; Alessandri, Louisa M; O’Sullivan, Fiona; Burton, Paul R; Pemberton, Patrick J; Stanley, Fiona J

    1998-01-01

    Objective To ascertain antepartum predictors of newborn encephalopathy in term infants. Design Population based, unmatched case-control study. Setting Metropolitan area of Western Australia, June 1993 to September 1995. Subjects All 164 term infants with moderate or severe newborn encephalopathy; 400 randomly selected controls. Main outcome measures Adjusted odds ratio estimates. Results The birth prevalence of moderate or severe newborn encephalopathy was 3.8/1000 term live births. The neonatal fatality was 9.1%. The risk of newborn encephalopathy increased with increasing maternal age and decreased with increasing parity. There was an increased risk associated with having a mother who was unemployed (odds ratio 3.60), an unskilled manual worker (3.84), or a housewife (2.48). Other risk factors from before conception were not having private health insurance (3.46), a family history of seizures (2.55), a family history of neurological disease (2.73), and infertility treatment (4.43). Risk factors during pregnancy were maternal thyroid disease (9.7), severe pre-eclampsia (6.30), moderate or severe bleeding (3.57), a clinically diagnosed viral illness (2.97), not having drunk alcohol (2.91); and placenta described at delivery as abnormal (2.07). Factors related to the baby were birth weight adjusted for gestational age between the third and ninth centile (4.37) or below the third centile (38.23). The risk relation with gestational age was J shaped with 38 and 39 weeks having the lowest risk. Conclusions The causes of newborn encephalopathy are heterogeneous and many of the causal pathways start before birth. Key messagesThe birth prevalence of moderate or severe newborn encephalopathy was 3.8 per 1000 term live births and the neonatal case fatality was 9.1%Independent risk factors before conception and in the antepartum period for newborn encephalopathy include socioeconomic status, family history of seizures or other neurological disease, conception after

  19. Carotid intima-media thickness in mainly non-obese women with polycystic ovary syndrome and age-matched controls.

    Science.gov (United States)

    Kim, Jin Ju; Choi, Young Min; Kang, Jin Hwa; Hwang, Kyu Ri; Chae, Soo Jin; Kim, Sun Mie; Ku, Seung Yup; Kim, Seok Hyun; Kim, Jung Gu; Moon, Shin Yong

    2013-07-01

    Metabolic disturbances are well-recognized clinical features of polycystic ovary syndrome (PCOS). Carotid intima-media thickness (CIMT) has been widely used as a surrogate marker of atherosclerosis and cardiovascular disease (CVD). CIMT in women with PCOS has been investigated in many studies, but there has been only one report in the Korean population. The aim of the present study was to compare the presence of subclinical atherosclerosis in young untreated Korean women with PCOS and age-matched controls, specifically by measuring their CIMT. CIMT was measured by one radiologist in 56 PCOS patients and 56 controls. To compare the CIMT according to PCOS phenotypes, women with PCOS were divided into two subgroups according to the presence of hyperandrogenism. Although PCOS patients were more obese and had higher blood pressure and insulin resistance index than the age-matched controls, the CIMT was not different between the two groups (0.49 ± 0.09 mm in PCOS patients vs. 0.50 ± 0.11 mm in controls, respectively, p = 0.562). When the CIMT in the control group was compared with hyperandrogenic and non-hyperandrogenic PCOS groups, also no significant differences were found. Despite the significant differences in some vascular risk factors between women with PCOS and controls, PCOS patients did not have a significantly higher CIMT (even in the hyperandrogenic subgroups). Although our study did not show the increased risk of subclinical atherosclerosis in PCOS patients, the role of CIMT continues to be investigated considering the importance of screening and monitoring CVD risk factors in women with PCOS.

  20. Suitability for use of open market operations as a main tool of monetary control by the National bank of Moldova

    Directory of Open Access Journals (Sweden)

    Larisa MISTREAN

    2016-06-01

    Full Text Available The open-market have become the main instrument of monetary control in the developed countries, increased flexibility offered, from the point of view of volume of the monetary policy operations initiated by the central bank. They permit the establishment of impersonal relations between market participants, as well as inefficiency and to avoid market and of the economy, as a result of the direct control.

  1. [Intra-uterine growth restriction impact on maternal serum concentration of PlGF (placental growth factor): A case control study].

    Science.gov (United States)

    Margossian, A; Boisson-Gaudin, C; Subtil, F; Rudigoz, R-C; Dubernard, G; Allias, F; Huissoud, C

    2016-01-01

    Placental growth factor (PlGF) is a pro-angiogenic factor mainly assessed in preeclampsia in which its blood concentration is decreased. The aim of this study was to dose the blood concentration of PlGF in women with fetal intra-uterine growth restriction (IUGR) without associated preeclampsia at the time of diagnosis. Case/control study: IUGR was defined by a fetal biometry with abnormal uterine and/or umbilical doppler (n=23). This group was compared to a control group of fetuses (n=25) matched for gestational age at blood sampling for the dosage of maternal seric PlGF. Women with preeclampsia were not included. The plasma PlGF concentration was 11pg/mL (IQR [11-42,8]) in the IUGR group vs 287pg/mL [135-439] in the control group (P<0.001) and this difference was available after adjustment for gestational age at the time of blood sampling (P<0.001). PlGF sensitivity and specificity for discrimination were respectively 87% (CI 95% [66-97]) and 88% (CI 95% [69-97]). Maternal serum PlGF concentrations were very low in IUGR group compared with those of the control group. Copyright © 2015. Published by Elsevier SAS.

  2. [Current situation and impact factors of acid deposition in main cites of Shandong Province].

    Science.gov (United States)

    Jia, Hong-yu; Zhang, Qiao-xian; Deng, Hong-bing; Zhao, Jing-zhu; Mu, Jin-bo; Zhang, De-zhi

    2006-12-01

    Based on the monitoring data for years in Shandong Province, current situation of acid rain in every city was assessed, and the temporal distribution of the dry, wet and total sulfur deposition in Jinan and Qingdao were studied. The results showed that Qingdao which had the largest precipitation acidity was the single city whose annul average precipitation pH was below 5. 60. The precipitation acidities in the main cities of Shandong Province were in a descent tendency. The total sulfur desposition in Jinan and Qingdao was basically stable or in a descent tendency, but also reached 10 t/(km(2)x a) or so. Among the total sulfur deposition flux, the dry deposition of sulfur had the greater contribution, and the contribution of SO2 dry deposition was higher than that of SO42- dry deposition. By analyzing the relation between the precipitation acidity and the SO2 discharge intensity, soil acidity and meteorological condition, the impact factors of acid precipitation in the cities of Shandong Province were revealed.

  3. Rates of the main thermonuclear reactions

    International Nuclear Information System (INIS)

    Abramovich, S.N.; Guzhovskii, B.Ya.; Dunaeva, S.A.; Fomushkin, E.F.

    1992-01-01

    The data on the cross sections of main thermonuclear reactions have been estimated with an account of the latest experimental results in a form of S-factor spline presentation. Based on this estimation, the reates of these reactions in 0.0001-1 MeV temperature range in the supposition of Maxwell distribution of relative velocities have been computed. The Maxwell-Boltzmann averaged -factors were calculated according to the table values of the reaction rates. Then the -factors were approximated with the 3 order spline-function. The necessity of the account of electron shielding and intramolecular movement at low temperatures is discussed (orig.)

  4. Risk and resilience factors in coping with daily stress in adulthood: the role of age, self-concept incoherence, and personal control.

    Science.gov (United States)

    Diehl, Manfred; Hay, Elizabeth L

    2010-09-01

    This study observed young, middle-aged, and older adults (N = 239; Mage = 49.6 years; range = 18-89 years) for 30 consecutive days to examine the association between daily stress and negative affect, taking into account potential risk (i.e., self-concept incoherence) and resilience (i.e., age, perceived personal control) factors. Results indicated that younger individuals and individuals with a more incoherent self-concept showed higher average negative affect across the study. As well, individuals reported higher negative affect on days that they experienced more stress than usual and on days that they reported less control than usual. These main effects were qualified by significant interactions. In particular, the association between daily stress and negative affect was stronger on days on which adults reported low control compared with days on which they reported high control (i.e., perceptions of control buffered stress). Reactivity to daily stress did not differ for individuals of different ages or for individuals with different levels of self-concept incoherence. Although all individuals reported higher negative affect on days on which they reported less control than usual, this association was more pronounced among younger adults. The current study helps to elucidate the role of risk and resilience factors when adults are faced with daily stress.

  5. Project evaluation: main characteristics

    OpenAIRE

    Moutinho, Nuno

    2010-01-01

    — The evaluation process of real investment projects must consider not only the traditional financial approach, but also non-financial aspects. Non financial analysis can provide additional relevant information about projects. We investigate financial and non-financial areas most relevant in project appraisal. We present main critical success factors and areas of analysis that lead to the perception of project success. Finally, companies are segmented to verify its financial and non-financial...

  6. Human Factors Engineering Aspects of Modifications in Control Room Modernization

    Energy Technology Data Exchange (ETDEWEB)

    Hugo, Jacques [Idaho National Lab. (INL), Idaho Falls, ID (United States); Clefton, Gordon [Idaho National Lab. (INL), Idaho Falls, ID (United States); Joe, Jeffrey [Idaho National Lab. (INL), Idaho Falls, ID (United States)

    2017-06-01

    This report describes the basic aspects of control room modernization projects in the U.S. nuclear industry and the need for supplementary guidance on the integration of human factors considerations into the licensing and regulatory aspects of digital upgrades. The report pays specific attention to the integration of principles described in NUREG-0711 (Human Factors Engineering Program Review Model) and how supplementary guidance can help to raise general awareness in the industry regarding the complexities of control room modernization projects created by many interdependent regulations, standards and guidelines. The report also describes how human factors engineering principles and methods provided by various resources and international standards can help in navigating through the process of licensing digital upgrades. In particular, the integration of human factors engineering guidance and requirements into the process of licensing digital upgrades can help reduce uncertainty related to development of technical bases for digital upgrades that will avoid the introduction of new failure modes.

  7. Development of human factors experimental evaluation techniques - Human factors design and evaluation of the main control room of atomic power plants using visual display terminals

    Energy Technology Data Exchange (ETDEWEB)

    Han, Sung Ho; Chung, Min Kyun; Choi, Kyung Lim; Song, Young Woong; Eoh, Hong Joon; Lee, In Suk; Kim, Bom Soo; Yeo, Yun Shin; Lee, Haeo Sun [Pohang University of Science and Technology, Pohang (Korea, Republic of)

    1995-07-01

    This study was conducted to build a prototype of the operator interface on a visual display terminal, and to provide a framework for using and applying prototyping techniques. A typical subsystem of an MCR was prototyped and validated by operator testing. Lessons learned during the development as well as prototyping techniques were described in this report for an efficient development. In addition, human factors experimental plans were surveyed and summarized for evaluating new design alternatives as well as the current design of the operator interface. The major results of this study are listed as follow: A method for designing an operator interface prototype on a VDT, A prototype of the operator interface of a typical subsystem, Guidelines for applying prototyping techniques, Characteristics and major considerations of experimental plans, Guidelines for applying prototyping techniques, Characteristics and major considerations of experimental plans, Guidelines for analyzing experimental data, A paradigm for human factors experimentation including experimental designs, procedures, and data analyses. 27 refs., 60 tabs., 47 figs. (author)

  8. Factors influencing the control strategy of hybrid drive of urban public transport buses

    International Nuclear Information System (INIS)

    Barta, Dalibor; Mruzek, Martin

    2015-01-01

    The efficiency of each drives is dependent on many factors. Hybrid drives and specially the drives of urban public transport may be affected by other factors given by transport infrastructure or operational conditions. These factors condition the suitable configuration of the individual elements of hybrid drive and the establishment of good control strategy of such drive. The study of influencing factors of the control strategy is the aim of this paper. (full text)

  9. Risk factors for idiopathic orbital inflammation: a case-control study

    NARCIS (Netherlands)

    Bijlsma, Ward R.; van Gils, Carla H.; Paridaens, Dion; Mourits, Maarten P.; Kalmann, Rachel

    2011-01-01

    Objective To identify risk factors involved in the development of idiopathic orbital inflammation (IOI). Methods Case-control study of 69 adults who had had a first episode of IOI and 296 adult controls with rhegmatogenous retinal detachment (RD) selected from three orbital centres in The

  10. Analysis of containment parameters during the main steam line break with the failure of the feedwater control valves

    International Nuclear Information System (INIS)

    Fabjan, L.; Petelin, S.; Mavko, B.; Gortnar, O.; Tiselj, I.

    1992-01-01

    U.S. Nuclear Regulatory Commission (NRC) information notice 91-69: 'Errors in Main Steam Line Break Analyses for Determining Containment Parameters' shows the possibility of an accident which could lead to beyond design containment pressure and temperature. Such accident would be caused by the continuation of feedwater flow following a main stream line break (MSLB) inside the containment. Krsko power plant already experienced problems with main feedwater control valves. For that reason, analysis of MSLB has been performed taking into account continuous feedwater addition scenario and different containment safety systems capabilities availability. Steam and water released into the containment during MSLB was calculated using RELAP5/MOD2 computer code. The containment response to MSLB was calculated using CONTEMPT-LT/028 computer code. The results indicated that the continuous feedwater flow following a MSLB could lead to beyond design containment pressure. The peak pressure and temperature depend on isolation time for main- and auxiliary-feedwater supply. In the case of low boron concentration injection, the core recriticality is characteristic for this type of accidents. It was concluded that the presented analysis of MSLB with continuous feedwater addition scenario is the worst case for containment design

  11. Individual and occupational risk factors for knee osteoarthritis – Study protocol of a case control study

    Directory of Open Access Journals (Sweden)

    Bouillon Bertil

    2008-02-01

    Full Text Available Abstract Background Knee osteoarthritis (OA is one of the frequent and functionally impairing disorders of the musculoskeletal system. In the literature, a number of occupational risk factors are discussed as being related to the development and progress of knee joint diseases, e.g. working in kneeling or squatting posture, lifting and carrying of heavy weights. The importance of the single risk factors and the possibility of prevention are currently under discussion. Besides the occupational factors, a number of individual risk factors are important, too. The distinction between work-related factors and individual factors is crucial in assessing the risk and in deriving preventive measures in occupational health. In existing studies, the occupational stress is determined mainly by surveys in employees and/or by making assumptions about individual occupations. Direct evaluation of occupational exposure has been performed only exceptionally. The aim of the research project ArGon is the assessment of different occupational factors in relation to individual factors (e.g. constitutional factors, leisure time activities, sports, which might influence the development and/or progression of knee (OA. The project is designed as a case control study. Methods/Design To raise valid data about the physical stress associated with occupational and leisure time activities, patients with and without knee OA are questioned by means of a standardised questionnaire and an interview. The required sample size was estimated to 800 cases and an equal number of controls. The degree and localisation of the knee cartilage or joint damages in the cases are documented on the basis of radiological, arthroscopic and/or operative findings in a patient record. Furthermore, occupational exposure is analysed at selected workplaces. To evaluate the answers provided in the questionnaire, work analysis is performed. Discussion In this research project, specific information on the

  12. Prostate cancer: The main risk and protective factors-Epigenetic modifications.

    Science.gov (United States)

    Adjakly, Mawussi; Ngollo, Marjolaine; Dagdemir, Aslihan; Judes, Gaëlle; Pajon, Amaury; Karsli-Ceppioglu, Seher; Penault-Llorca, Frédérique; Boiteux, Jean-Paul; Bignon, Yves-Jean; Guy, Laurent; Bernard-Gallon, Dominique

    2015-02-01

    With 13 million new cases worldwide every year, prostate cancer is as a very real public health concern. Prostate cancer is common in over-50s men and the sixth-leading cause of cancer-related death in men worldwide. Like all cancers, prostate cancer is multifactorial - there are non-modifiable risk factors like heredity, ethnicity and geographic location, but also modifiable risk factors such as diet. Diet-cancer linkages have risen to prominence in the last few years, with accruing epidemiological data pointing to between-population incidence differentials in numerous cancers. Indeed, there are correlations between fat-rich diet and risk of hormone-dependent cancers like prostate cancer and breast cancer. Diet is a risk factor for prostate cancer, but certain micronutrients in specific diets are considered protective factors against prostate cancer. Examples include tomato lycopene, green tea epigallocatechin gallate, and soy phytoestrogens. These micronutrients are thought to exert cancer-protective effects via anti-oxidant pathways and inhibition of cell proliferation. Here, we focus in on the effects of phytoestrogens, and chiefly genistein and daidzein, which are the best-researched to date. Soy phytoestrogens are nonsteroid molecules whose structural similarity lends them the ability to mimic the effects of 17ß-estradiol. On top of anti-oxidant effects, there is evidence that soy phytoestrogens can modulate the epigenetic modifications found in prostate cancer. We also studied the impact of phytoestrogens on epigenetic modifications in prostate cancer, with special focus on DNA methylation, miRNA-mediated regulation and histone modifications. Copyright © 2014 Elsevier Masson SAS. All rights reserved.

  13. The transcription factor Prep1 controls hepatic insulin sensitivity and gluconeogenesis by targeting nuclear localization of FOXO1.

    Science.gov (United States)

    Kulebyakin, Konstantin; Penkov, Dmitry; Blasi, Francesco; Akopyan, Zhanna; Tkachuk, Vsevolod

    2016-12-02

    Liver plays a key role in controlling body carbohydrate homeostasis by switching between accumulation and production of glucose and this way maintaining constant level of glucose in blood. Increased blood glucose level triggers release of insulin from pancreatic β-cells. Insulin represses hepatic glucose production and increases glucose accumulation. Insulin resistance is the main cause of type 2 diabetes and hyperglycemia. Currently thiazolidinediones (TZDs) targeting transcriptional factor PPARγ are used as insulin sensitizers for treating patients with type 2 diabetes. However, TZDs are reported to be associated with cardiovascular and liver problems and stimulate obesity. Thus, it is necessary to search new approaches to improve insulin sensitivity. A promising candidate is transcriptional factor Prep1, as it was shown earlier it could affect insulin sensitivity in variety of insulin-sensitive tissues. The aim of the present study was to evaluate a possible involvement of transcriptional factor Prep1 in control of hepatic glucose accumulation and production. We created mice with liver-specific Prep1 knockout and discovered that hepatocytes derived from these mice are much more sensitive to insulin, comparing to their WT littermates. Incubation of these cells with 100 nM insulin results in almost complete inhibition of gluconeogenesis, while in WT cells this repression is only partial. However, Prep1 doesn't affect gluconeogenesis in the absence of insulin. Also, we observed that nuclear content of gluconeogenic transcription factor FOXO1 was greatly reduced in Prep1 knockout hepatocytes. These findings suggest that Prep1 may control hepatic insulin sensitivity by targeting FOXO1 nuclear stability. Copyright © 2016 Elsevier Inc. All rights reserved.

  14. Risk Factors Profile of Shoulder Dystocia in Oman: A Case Control Study

    OpenAIRE

    Maha M. Al-Khaduri; Rania Mohammed Abudraz; Sayed G. Rizvi; Yahya M. Al-Farsi

    2014-01-01

    Objective: This study aimed to assess the risk factor profile of shoulder dystocia and associated neonatal complications in Oman, a developing Arab country. Methods: A retrospective case-control study was conducted among 111 cases with dystocia and 111 controls, identified during 1994-2006 period in a tertiary care hospital in Oman. Controls were randomly selected among women who did not have dystocia, and were matched to cases on the day of delivery. Data related to potential risk factor...

  15. RISK FACTORS FOR VERY PRETERM DELIVERY

    Directory of Open Access Journals (Sweden)

    Наталья Витальевна Батырева

    2018-01-01

    Full Text Available The aim of the research – assess risk factors for very preterm delivery in the Omsk region. Materials and methods. The main group comprised women with very preterm delivery (n = 64; сomparison group – pregnant women with a threat of interruption in terms of 22-27 weeks and successful preserving therapy (n = 63; control group – pregnant women in whom this pregnancy was taking place without the threat of interruption (n = 62. Results. Risk factors for very preterm delivery were bacterial vaginosis, specific vaginitis, kidney disease and the threat of interruption. There was a significant lead in streptococci (32.3 ± 5.8 %, especially group B (19.0 ± 4.9 % in the main group. The risk factor for very preterm delivery was infectious viral diseases transferred during pregnancy, observed in 12.7 ± 4.2 % of women in the main group, in 7.8 ± 3.3 % in the comparison group (p < 0.01 and in 4.8 ± 2,7 % – control (p < 0,001. In the main group, placental insufficiency was 2 times more common than in the comparison group and 13 times than in the control group. Every sixth pregnant of the main group had manifestations of gestosis. Such complications of gestation as the premature detachment of the normally inserted placenta (7.8 ± 3.3 % and inborn malformations of a fruit (1.6 ± 1.6 % were observed only in the main group. Conclusion. The results of the research and literature data showed that the significant influence on the level of very early premature births is due to: the age of the parents, the abuse of nicotine, alcohol, drugs, abortion, preterm birth, urinary tract and genital tract infections, severe somatic diseases, multiple pregnancies. In the structure of complications of gestation during miscarriages, placental insufficiency predominates, the threat of abortion, fetal growth retardation, and polyhydramnios.

  16. Fine scale spatial variability of microbial pesticide degradation in soil: scales, controlling factors, and implications

    DEFF Research Database (Denmark)

    Dechesne, Arnaud; Badawi, N.; Aamand, Jens

    2014-01-01

    across pesticide classes: they include some soil characteristics (pH) and some agricultural management practices (pesticide application, tillage), while other potential controlling factors have more conflicting effects depending on the site or the pesticide. Evidence demonstrating the importance......Pesticide biodegradation is a soil microbial function of critical importance for modern agriculture and its environmental impact. While it was once assumed that this activity was homogeneously distributed at the field scale, mounting evidence indicates that this is rarely the case. Here, we...... critically examine the literature on spatial variability of pesticide biodegradation in agricultural soil. We discuss the motivations, methods, and main findings of the primary literature. We found significant diversity in the approaches used to describe and quantify spatial heterogeneity, which complicates...

  17. Does behaviour modification affect post-stroke risk factor control? Three-year follow-up of a randomized controlled trial.

    Science.gov (United States)

    McManus, Julie Ann; Craig, Alison; McAlpine, Christine; Langhorne, Peter; Ellis, Graham

    2009-02-01

    Little is known about the long-term effectiveness after stroke of interventions for behaviour modification and ensuring concordance with therapies. We describe a follow-up study of a previous randomized controlled trial of a brief period of behaviour modification. The aim of this study was to determine outcomes three years after the initial intervention. Survivors of the original cohort were contacted and asked to attend for follow-up interview, within a geriatric day hospital. This study was carried out in the Geriatric Day Hospital at Stobhill Hospital, Balornock Road, Glasgow. Details of risk factor control, including blood pressure, cholesterol levels and diabetic control, were assessed. Questionnaires used in the initial study were repeated including the Geriatric Depression Scale score, Euroqol Perceived Health Status and Stroke Services Satisfaction Questionnaire. Primary outcome was collective risk factor control. Clinical outcomes including recurrent cerebrovascular events, medication persistence and perceived health status were also recorded. Mean length of follow-up was 3.6 years (SD 0.43). Of the 205 patients enrolled in the initial study, 102 patients attended for repeat interview(49 intervention/53 control). There were no significant differences in the percentage of controlled risk factors between groups (intervention 51.7% versus control 55.9%, P = 0.53). Similarities were observed in the number of recurrent clinical events and medication persistence between groups. No overall difference was observed in perceived health status, satisfaction with care or depression scores. Brief intervention with respect to behaviour modification and risk factor control does not appear to have any long-term benefit. These results must be cautiously interpreted in light of the small study number and further research is required.

  18. [Risk factors associated to preclampsia].

    Science.gov (United States)

    López-Carbajal, Mario Joaquín; Manríquez-Moreno, María Esther; Gálvez-Camargo, Daniela; Ramírez-Jiménez, Evelia

    2012-01-01

    preeclampsia constitutes one of the main causes of maternal and perinatal morbidity and mortality. The aim was to identify the risk factors associated to the developmental of preeclampsia mild-moderate and severe, as well as the force of association of these factors in a hospital of second-level medical care. study of cases and controls, a relation 1:1, in women withdrawn of the Service of Gynecology and Obstetrics during 2004 to 2007. Pregnant women with more than 20 weeks gestation were included. In the cases group we included patients with diagnosis of preeclampsia mild-moderate or severe (corroborated clinical and laboratory). In the controls group that had a normal childbirth without pathology during the pregnancy. 42 cases and 42 controls. The average age was of 27 years. The associated risk factors were overweight, obesity, irregular prenatal control, short or long intergenesic period, history of caesarean or preeclampsia in previous pregnancies. the knowledge of the risk factors will allow the accomplishment of preventive measures and decrease the fetal and maternal morbidity and mortality due to preeclampsia.

  19. Impact of implementing electronic clinical practice guidelines for the diagnosis, control and treatment of cardiovascular risk factors: A pre-post controlled study.

    Science.gov (United States)

    Comin, Eva; Catalan-Ramos, Arantxa; Iglesias-Rodal, Manuel; Grau, Maria; Del Val, Jose Luis; Consola, Alicia; Amado, Ester; Pons, Angels; Mata-Cases, Manel; Franzi, Alicia; Ciurana, Ramon; Frigola, Eva; Cos, Xavier; Davins, Josep; Verdu-Rotellar, Jose M

    To evaluate the impact of computerized clinical practice guidelines on the management, diagnosis, treatment, control, and follow-up of the main cardiovascular risk factors: hypertension, hypercholesterolaemia, and type 2 diabetes mellitus. Pre-post controlled study. Catalonia, autonomous community located in north-eastern Spain. Individuals aged 35-74 years assigned to general practitioners of the Catalan Health Institute. The intervention group consisted of individuals whose general practitioners had accessed the computerized clinical practice guidelines at least twice a day, while the control group consisted of individuals whose general practitioner had never accessed the computerized clinical practice guidelines platform. The Chi-squared test was used to detect significant differences in the follow-up, control, and treatment variables for all three disorders (hypertension, hypercholesterolaemia, and type 2 diabetes mellitus) between individuals assigned to users and non-users of the computerized clinical practice guidelines, respectively. A total of 189,067 patients were included in this study, with a mean age of 56 years (standard deviation 12), and 55.5% of whom were women. Significant differences were observed in hypertension management, treatment and control; type 2 diabetes mellitus management, treatment and diagnoses, and the management and control of hypercholesterolaemia in both sexes. Computerized clinical practice guidelines are an effective tool for the control and follow-up of patients diagnosed with hypertension, type 2 diabetes mellitus, and hypercholesterolaemia. The usefulness of computerized clinical practice guidelines to diagnose and adequately treat individuals with these disorders remains unclear. Copyright © 2016 Elsevier España, S.L.U. All rights reserved.

  20. Integrated application of human factors to a power plant control room information system

    International Nuclear Information System (INIS)

    Fish, H.C. Jr.; Gutierrez, R.

    1988-01-01

    The human factors plan was developed as a methodology to apply human factors from the conceptual design of the EPIC system to the functional verification conducted at the plant. An integral part of the Human Factors Plan was the Functional Verification Plan. Developed in parallel, this second plan and its resultant programs verified functional appropriateness of the SPDS display, NSSS displays, EOP displays, man-machine interfaces (MMI), and workstation designs. The functional verification process was performed at the hardware/software developer's factory and at the JAFNPP, following installation of the EPIC system. Because the EPIC system replaces existing control room equipment, it is important that human factors be applied in a systematic manner consistent with other control room displays and controls. To ensure that this goal was met, a human factors plan was developed

  1. Epigenetic control of hypoxia inducible factor-1α-dependent expression of placental growth factor in hypoxic conditions.

    Science.gov (United States)

    Tudisco, Laura; Della Ragione, Floriana; Tarallo, Valeria; Apicella, Ivana; D'Esposito, Maurizio; Matarazzo, Maria Rosaria; De Falco, Sandro

    2014-04-01

    Hypoxia plays a crucial role in the angiogenic switch, modulating a large set of genes mainly through the activation of hypoxia-inducible factor (HIF) transcriptional complex. Endothelial cells play a central role in new vessels formation and express placental growth factor (PlGF), a member of vascular endothelial growth factor (VEGF) family, mainly involved in pathological angiogenesis. Despite several observations suggest a hypoxia-mediated positive modulation of PlGF, the molecular mechanism governing this regulation has not been fully elucidated. We decided to investigate if epigenetic modifications are involved in hypoxia-induced PlGF expression. We report that PlGF expression was induced in cultured human and mouse endothelial cells exposed to hypoxia (1% O 2), although DNA methylation at the Plgf CpG-island remains unchanged. Remarkably, robust hyperacetylation of histones H3 and H4 was observed in the second intron of Plgf, where hypoxia responsive elements (HREs), never described before, are located. HIF-1α, but not HIF-2α, binds to identified HREs. Noteworthy, only HIF-1α silencing fully inhibited PlGF upregulation. These results formally demonstrate a direct involvement of HIF-1α in the upregulation of PlGF expression in hypoxia through chromatin remodeling of HREs sites. Therefore, PlGF may be considered one of the putative targets of anti-HIF therapeutic applications.

  2. Main and interaction effects of extrusion temperature and usage ...

    African Journals Online (AJOL)

    ali

    2012-10-30

    Oct 30, 2012 ... The main and interaction effects of three extrusion ... oil extraction and allow the use of a homegrown protein supplement in the .... Statistical analysis. The main and .... acceptable level of antitrypsin factor is 4 mg/g; this level.

  3. Nuclear factor erythroid 2-related factor-2 activity controls 4-hydroxynonenal metabolism and activity in prostate cancer cells.

    Science.gov (United States)

    Pettazzoni, Piergiorgio; Ciamporcero, Eric; Medana, Claudio; Pizzimenti, Stefania; Dal Bello, Federica; Minero, Valerio Giacomo; Toaldo, Cristina; Minelli, Rosalba; Uchida, Koji; Dianzani, Mario Umberto; Pili, Roberto; Barrera, Giuseppina

    2011-10-15

    4-Hydroxynonenal (HNE) is an end product of lipoperoxidation with antiproliferative and proapoptotic properties in various tumors. Here we report a greater sensitivity to HNE in PC3 and LNCaP cells compared to DU145 cells. In contrast to PC3 and LNCaP cells, HNE-treated DU145 cells showed a smaller reduction in growth and did not undergo apoptosis. In DU145 cells, HNE did not induce ROS production and DNA damage and generated a lower amount of HNE-protein adducts. DU145 cells had a greater GSH and GST A4 content and GSH/GST-mediated HNE detoxification. Nuclear factor erythroid 2-related factor-2 (Nrf2) is a regulator of the antioxidant response. Nrf2 protein content and nuclear accumulation were higher in DU145 cells compared to PC3 and LNCaP cells, whereas the expression of KEAP1, the main negative regulator of Nrf2 activity, was lower. Inhibition of Nrf2 expression with specific siRNA resulted in a reduction in GST A4 expression and GS-HNE formation, indicating that Nrf2 controls HNE metabolism. In addition, Nrf2 knockdown sensitized DU145 cells to HNE-mediated antiproliferative and proapoptotic activity. In conclusion, we demonstrated that increased Nrf2 activity resulted in a reduction in HNE sensitivity in prostate cancer cells, suggesting a potential mechanism of resistance to pro-oxidant therapy. Copyright © 2011 Elsevier Inc. All rights reserved.

  4. Effect of main injection timing for controlling the combustion phasing of a homogeneous charge compression ignition engine using a new dual injection strategy

    International Nuclear Information System (INIS)

    Das, Pranab; Subbarao, P.M.V.; Subrahmanyam, J.P.

    2015-01-01

    Highlights: • A new dual injection concept is developed by minimum geometry modification. • The occurrence of combustion parameters strongly depend on main injection timing. • At higher load, premixed equivalence ratio dominates over main injection timing. • Retarded of main injection timing tends to retard combustion phasing. • Slightly retarded main injection timing is recommended to avoid intense knocking. - Abstract: Homogeneous charge compression ignition combustion of diesel fuel is implemented using a novel dual injection strategy. A new experimental technique is developed to modify a single cylinder direct injection diesel engine to run on homogeneous combustion mode. Effect of main injection timing is investigated covering a range from 26 to 8 crank angle degrees before top dead center with an interval of 3°. Retarded main injection timing is identified as a control strategy for delaying combustion phasing and a means of controlled combustion phasing of direct injection homogeneous charge compression ignition combustion. Two load conditions were investigated and it was observed that at higher load, start of combustion depends more on fuel air equivalence ratio than main injection timing, whereas at low load, it significantly varies with varying main injection timing. Significant improvements in smoke and oxides of nitrogen emissions are observed when compared with the baseline conventional combustion. By studying different combustion parameters, it is observed that there is an improvement in performance and emissions with marginal loss in thermal efficiency when the main injection timing is 20° before top dead center. This is identified as the optimum main injection timing for such homogeneous combustion under the same operating condition

  5. [Integrated Management Area of Vascular Risk: A new organisational model for global control of risk factors].

    Science.gov (United States)

    Armario, P; Jericó, C; Vila, L; Freixa, R; Martin-Castillejos, C; Rotllan, M

    Cardiovascular disease (CVD), is a major cause of morbidity and mortality that increases the cost of care. Currently there is a low degree of control of the main cardiovascular risk factors, although we have a good therapeutic arsenal. To achieve the improvement of this reality, a good coordination and multidisciplinary participation are essential. The development of new organizational models such as the Integrated Management Area of Vascular Risk can facilitate the therapeutic harmonization and unification of the health messages offered by different levels of care, based on clinical practice guidelines, in order to provide patient-centred integrated care. Copyright © 2016 SEH-LELHA. Publicado por Elsevier España, S.L.U. All rights reserved.

  6. Extended daily dialysis in acute kidney injury patients: metabolic and fluid control and risk factors for death.

    Directory of Open Access Journals (Sweden)

    Daniela Ponce

    Full Text Available Intermittent hemodialysis (IHD and continuous renal replacement therapies (CRRT are used as Acute Kidney Injury (AKI therapy and have certain advantages and disadvantages. Extended daily dialysis (EDD has emerged as an alternative to CRRT in the management of hemodynamically unstable AKI patients, mainly in developed countries.We hypothesized that EDD is a safe option for AKI treatment and aimed to describe metabolic and fluid control of AKI patients undergoing EDD and identify complications and risk factors associated with death.This is an observational and retrospective study describing introduction of EDD at our institution. A total of 231 hemodynamically unstable AKI patients (noradrenalin dose between 0.3 and 1.0 ucg/kg/min were assigned to 1367 EDD session. EDD consisted of 6-8 h of HD 6 days a week, with blood flow of 200 ml/min, dialysate flows of 300 ml/min.Mean age was 60.6±15.8 years, 97.4% of patients were in the intensive care unit, and sepsis was the main etiology of AKI (76.2. BUN and creatinine levels stabilized after four sessions at around 38 and 2.4 mg/dl, respectively. Fluid balance decreased progressively and stabilized around zero after five sessions. Weekly delivered Kt/V was 5.94±0.7. Hypotension and filter clotting occurred in 47.5 and 12.4% of treatment session, respectively. Regarding AKI outcome, 22.5% of patients presented renal function recovery, 5.6% of patients remained on dialysis after 30 days, and 71.9% of patients died. Age and focus abdominal sepsis were identified as risk factors for death. Urine output and negative fluid balance were identified as protective factors.EDD is effective for AKI patients, allowing adequate metabolic and fluid control. Age, focus abdominal sepsis, and lower urine output as well as positive fluid balance after two EDD sessions were associated significantly with death.

  7. Human-factors engineering-control-room design review: Shoreham Nuclear Power Station. Draft audit report

    International Nuclear Information System (INIS)

    Peterson, L.R.; Preston-Smith, J.; Savage, J.W.; Rousseau, W.F.

    1981-01-01

    A human factors engineering preliminary design review of the Shoreham control room was performed at the site on March 30 through April 3, 1981. This design review was carried out by a team from the Human Factors Engineering Branch, Division of Human Factors Safety. This report was prepared on the basis of the HFEB's review of the applicant's Preliminary Design Assessment and the human factors engineering design review/audit performed at the site. The presented sections are numbered to conform to the guidelines of the draft version of NUREG-0700. They summarize the teams's observations of the control room design and layout, and of the control room operators' interface with the control room environment

  8. Ranking malaria risk factors to guide malaria control efforts in African highlands.

    Science.gov (United States)

    Protopopoff, Natacha; Van Bortel, Wim; Speybroeck, Niko; Van Geertruyden, Jean-Pierre; Baza, Dismas; D'Alessandro, Umberto; Coosemans, Marc

    2009-11-25

    Malaria is re-emerging in most of the African highlands exposing the non immune population to deadly epidemics. A better understanding of the factors impacting transmission in the highlands is crucial to improve well targeted malaria control strategies. A conceptual model of potential malaria risk factors in the highlands was built based on the available literature. Furthermore, the relative importance of these factors on malaria can be estimated through "classification and regression trees", an unexploited statistical method in the malaria field. This CART method was used to analyse the malaria risk factors in the Burundi highlands. The results showed that Anopheles density was the best predictor for high malaria prevalence. Then lower rainfall, no vector control, higher minimum temperature and houses near breeding sites were associated by order of importance to higher Anopheles density. In Burundi highlands monitoring Anopheles densities when rainfall is low may be able to predict epidemics. The conceptual model combined with the CART analysis is a decision support tool that could provide an important contribution toward the prevention and control of malaria by identifying major risk factors.

  9. Risk Factors for Campylobacteriosis of Chicken, Ruminant, and Environmental Origin: A Combined Case-Control and Source Attribution Analysis

    Science.gov (United States)

    Wagenaar, Jaap A.; de Boer, Albert G.; Havelaar, Arie H.; Friesema, Ingrid H. M.; French, Nigel P.; Busani, Luca; van Pelt, Wilfrid

    2012-01-01

    Background Campylobacteriosis contributes strongly to the disease burden of food-borne pathogens. Case-control studies are limited in attributing human infections to the different reservoirs because they can only trace back to the points of exposure, which may not point to the original reservoirs because of cross-contamination. Human Campylobacter infections can be attributed to specific reservoirs by estimating the extent of subtype sharing between strains from humans and reservoirs using multilocus sequence typing (MLST). Methodology/Principal Findings We investigated risk factors for human campylobacteriosis caused by Campylobacter strains attributed to different reservoirs. Sequence types (STs) were determined for 696 C. jejuni and 41 C. coli strains from endemic human cases included in a case-control study. The asymmetric island model, a population genetics approach for modeling Campylobacter evolution and transmission, attributed these cases to four putative animal reservoirs (chicken, cattle, sheep, pig) and to the environment (water, sand, wild birds) considered as a proxy for other unidentified reservoirs. Most cases were attributed to chicken (66%) and cattle (21%), identified as the main reservoirs in The Netherlands. Consuming chicken was a risk factor for campylobacteriosis caused by chicken-associated STs, whereas consuming beef and pork were protective. Risk factors for campylobacteriosis caused by ruminant-associated STs were contact with animals, barbecuing in non-urban areas, consumption of tripe, and never/seldom chicken consumption. Consuming game and swimming in a domestic swimming pool during springtime were risk factors for campylobacteriosis caused by environment-associated STs. Infections with chicken- and ruminant-associated STs were only partially explained by food-borne transmission; direct contact and environmental pathways were also important. Conclusion/Significance This is the first case-control study in which risk factors for

  10. Risk factors for campylobacteriosis of chicken, ruminant, and environmental origin: a combined case-control and source attribution analysis.

    Directory of Open Access Journals (Sweden)

    Lapo Mughini Gras

    Full Text Available BACKGROUND: Campylobacteriosis contributes strongly to the disease burden of food-borne pathogens. Case-control studies are limited in attributing human infections to the different reservoirs because they can only trace back to the points of exposure, which may not point to the original reservoirs because of cross-contamination. Human Campylobacter infections can be attributed to specific reservoirs by estimating the extent of subtype sharing between strains from humans and reservoirs using multilocus sequence typing (MLST. METHODOLOGY/PRINCIPAL FINDINGS: We investigated risk factors for human campylobacteriosis caused by Campylobacter strains attributed to different reservoirs. Sequence types (STs were determined for 696 C. jejuni and 41 C. coli strains from endemic human cases included in a case-control study. The asymmetric island model, a population genetics approach for modeling Campylobacter evolution and transmission, attributed these cases to four putative animal reservoirs (chicken, cattle, sheep, pig and to the environment (water, sand, wild birds considered as a proxy for other unidentified reservoirs. Most cases were attributed to chicken (66% and cattle (21%, identified as the main reservoirs in The Netherlands. Consuming chicken was a risk factor for campylobacteriosis caused by chicken-associated STs, whereas consuming beef and pork were protective. Risk factors for campylobacteriosis caused by ruminant-associated STs were contact with animals, barbecuing in non-urban areas, consumption of tripe, and never/seldom chicken consumption. Consuming game and swimming in a domestic swimming pool during springtime were risk factors for campylobacteriosis caused by environment-associated STs. Infections with chicken- and ruminant-associated STs were only partially explained by food-borne transmission; direct contact and environmental pathways were also important. CONCLUSION/SIGNIFICANCE: This is the first case-control study in which risk

  11. Main control system verification and validation of NPP digital I and C system based on engineering simulator

    International Nuclear Information System (INIS)

    Lin Meng; Hou Dong; Liu Pengfei; Yang Zongwei; Yang Yanhua

    2010-01-01

    Full-scope digital instrumentation and controls system (I and C) technique is being introduced in Chinese new constructed Nuclear Power Plant (NPP), which mainly includes three parts: control system, reactor protection system and engineered safety feature actuation system. For example, SIEMENS TELEPERM XP and XS distributed control system (DCS) have been used in Ling Ao Phase II NPP, which is located in Guangdong province, China. This is the first NPP project in China that Chinese engineers are fully responsible for all the configuration of actual analog and logic diagram, although experience in NPP full-scope digital I and C is very limited. For the safety, it has to be made sure that configuration is right and control functions can be accomplished before the phase of real plant testing on reactor. Therefore, primary verification and validation (V and V) of I and C needs to be carried out. Except the common and basic way, i.e. checking the diagram configuration one by one according to original design, NPP engineering simulator is applied as another effective approach of V and V. For this purpose, a virtual NPP thermal-hydraulic model is established as a basis according to Ling Ao Phase II NPP design, and the NPP simulation tools can provide plant operation parameters to DCS, accept control signal from I and C and give response. During the test, one set of data acquisition equipments are used to build a connection between the engineering simulator (software) and SIEMENS DCS I/O cabinet (hardware). In this emulation, original diagram configuration in DCS and field hardware structures are kept unchanged. In this way, firstly judging whether there are some problems by observing the input and output of DCS without knowing the internal configuration. Then secondly, problems can be found and corrected by understanding and checking the exact and complex configuration in detail. At last, the correctness and functionality of the control system are verified. This method is

  12. Active Power Factor Correction Using a Sliding Mode Controller

    Directory of Open Access Journals (Sweden)

    Korhan KAYIŞLI

    2008-03-01

    Full Text Available In this paper, a sliding mode controller is designed for active shaping of the input current in the boost converter. Robustness of the designed controller is tested with variable output voltage references, different loads and network voltage variations. For the simulations, MATLAB/Simulink programme is used. From simulation results, the same phase was provided between input current and input voltage and nearly unity power factor was obtained.

  13. Factors affecting sustainable animal trypanosomosis control in parts ...

    African Journals Online (AJOL)

    This study examined the factors affecting sustainable trypanosomiasis control in parts of Kaduna State within the sub-humid savannah ecological zone of Nigeria. Focus group discussions were ... More awareness and preference for pour-on and aerial spraying were higher than the use of traps, target or screens. Rearing of ...

  14. Exhaust constituent emission factors of printed circuit board pyrolysis processes and its exhaust control

    Energy Technology Data Exchange (ETDEWEB)

    Chiang, Hung-Lung, E-mail: hlchiang@mail.cmu.edu.tw [Department of Health Risk Management, China Medical University, Taichung, Taiwan (China); Lin, Kuo-Hsiung [Department of Environmental Engineering and Science, Fooyin University, Kaohsiung, Taiwan (China)

    2014-01-15

    Highlights: • Recycling of waste printed circuit boards is an important issue. • Pyrolysis is an emerging technology for PCB treatment. • Emission factors of VOCs are determined for PCB pyrolysis exhaust. • Iron-Al{sub 2}O{sub 3} catalyst was employed for the exhaust control. -- Abstract: The printed circuit board (PCB) is an important part of electrical and electronic equipment, and its disposal and the recovery of useful materials from waste PCBs (WPCBs) are key issues for waste electrical and electronic equipment. Waste PCB compositions and their pyrolysis characteristics were analyzed in this study. In addition, the volatile organic compound (VOC) exhaust was controlled by an iron-impregnated alumina oxide catalyst. Results indicated that carbon and oxygen were the dominant components (hundreds mg/g) of the raw materials, and other elements such as nitrogen, bromine, and copper were several decades mg/g. Exhaust constituents of CO, H{sub 2}, CH{sub 4}, CO{sub 2}, and NOx, were 60–115, 0.4–4.0, 1.1–10, 30–95, and 0–0.7 mg/g, corresponding to temperatures ranging from 200 to 500 °C. When the pyrolysis temperature was lower than 300 °C, aromatics and paraffins were the major species, contributing 90% of ozone precursor VOCs, and an increase in the pyrolysis temperature corresponded to a decrease in the fraction of aromatic emission factors. Methanol, ethylacetate, acetone, dichloromethane, tetrachloromethane and acrylonitrile were the main species of oxygenated and chlorinated VOCs. The emission factors of some brominated compounds, i.e., bromoform, bromophenol, and dibromophenol, were higher at temperatures over 400 °C. When VOC exhaust was flowed through the bed of Fe-impregnated Al{sub 2}O{sub 3}, the emission of ozone precursor VOCs could be reduced by 70–80%.

  15. Factors supporting dentist leaders' retention in leadership.

    Science.gov (United States)

    Tuononen, T; Lammintakanen, J; Suominen, A L

    2017-12-01

    The aim was to study factors associated with staying in a dentist leadership position. We used an electronic questionnaire to gather data from 156 current or former Finnish dentist leaders in 2014. Principal component analysis categorized statements regarding time usage and opportunities in managerial work into five main components. Associations between these main component scores and the tendency to stay as a leader were analyzed with logistic regression. Out of the five main components, two were significantly associated with staying as a leader: 'career intentions', which represented intent to continue or to leave the leadership position; and 'work time control opportunities', which represented how leaders could control their own work time. Other factors that supported staying were leadership education, more work time available for leadership work, and lower age. The main component 'work pressure' decreased, although not significantly, the odds of continuing; it included lack of leadership work time, and pressure from superiors or subordinates. Leaders have important roles in health care, ensuring everyday operations as well as developing their organizations to meet future challenges. Knowledge of these supporting factors will enable dentist leaders and their organizations to improve working conditions in order to recruit and retain motivated and competent persons. In addition, well-designed education is important to inspire and encourage future leaders. Copyright© 2017 Dennis Barber Ltd.

  16. [Asthma control status in children and related factors in 29 cities of China].

    Science.gov (United States)

    Zhao, Jing

    2013-02-01

    To investigate the status of asthma control in the city and severity of asthma in children and to identify related factors. This study was conducted in one children's hospital or tertiary hospital in each of the 29 provinces except Xinjiang and Xizang Autonomous Regions. Totally, 2960 parents with asthmatic children ages 0 to 14 years, and all had been diagnosed with asthma at least 3 months ago and the course was more than 12 months, who visited those hospitals were selected for the knowledge, attitude, and practice (KAP) questionnaire survey, and separated into the controlled asthma group and uncontrolled asthma group according to children's asthma conditions in the past 12 months. Multivariate analysis was carried out based on the answers to 28 tested factors; 2485 of 2960 questionnaires from 29 provinces were valid. Of the 2485 valid questionnaires, 66.0% asthmatic children had asthma attacks in the past 12 months, 26.8% asthmatic children had visited the emergency department, 16.2% asthmatic children had been hospitalized. The total cost was significantly higher in the uncontrolled group than in contro group (χ² = 23.14, P asthma control, knowledge of "3 or more times recurrent wheezing suggesting asthma", knowledge of "cough lasting for more than 4 weeks suggesting asthma", knowledge of "cough improved with bronchodilators suggesting asthma", knowledge of "awareness of using short-acting β₂ agonist for acute attack", avoiding contact with plush toys, adhere to use nasal steroid, inhaled corticosteroids/composite preparation, age of children and course of asthma in children are protective factors that affect asthma control and severity of asthma in children. Food allergies, eczema and family history of asthma are risk factors. Asthma in many children was poorly controlled. Factors that affect asthma control and severity include parents' knowledge about asthma, exposure to adverse environment, the compliance with medication and regular visits for asthma

  17. Characteristics and controlling factors of micropore structures of the Longmaxi Shale in the Jiaoshiba area, Sichuan Basin

    Directory of Open Access Journals (Sweden)

    Xusheng Guo

    2014-12-01

    Full Text Available Pore structures in shales are a main factor affecting the storage capacity and production performance of shale gas reservoirs. Taking Longmaxi Shales in the Jiaoshiba area of the Sichuan Basin as a study object, we systematically study the microscopic pore structures of shales by using Argon-ion polishing Scanning Electron Microscope (SEM, high-pressure mercury injection and low-temperature nitrogen adsorption and desorption experiments. The study results show that: the Longmaxi Shale in this area are dominated by nano-scale pores which can be classified into organic pores, inorganic pores (intergranular pores, intragranular pores, inter-crystalline pores and dissolution pores, microfractures (intragranular structure fractures, interlayer sliding fractures, diagenetic shrinkage joints and abnormal-pressure fractures from organic evolution, among which organic pores and clay mineral pores are predominant and organic pores are the most common; a TOC value shows an obvious positive correlation with the content of organic pores, which account for up to 50% in the lower-quality shales with a TOC of over 2% where they are most developed; microscopic pore structures are very complex and open, with pores being mainly in cylinder shape with two ends open, or in parallel tabular shape with four sides open and 2–30 nm in diameter, being mostly medium pores. On this basis, factors affecting the micropore structures of shales in this area are studied. It is concluded that organic matter abundance and thermal maturity are the major factors controlling the microscopic pore structures of shales, while the effects of clay mineral content are relatively insignificant.

  18. Analysis of the main factors affecting the evaluation of the dose in workplaces: the case of tourist caves

    International Nuclear Information System (INIS)

    Sainz, C.; Santiago Quindos, L.; Fuente, I.; Nicolas, J.; Quindos, L.

    2006-01-01

    Since 2001, Spanish law incorporated EURATOM basic standards for radiological protection, which include a request at the European Communities Member States to determine the working places on which exposure to natural radiation is significant. On Title VII (BOE 178/2001) radiation coming from natural sources has analogous role than radiation emitted from artificial ones used to. High concentrations of radon exist in several workplaces like tourist caves mainly because of the low ventilation rates existing at these enclosures. In this sense, in its 1990 publication, the ICRP recommended that high exposures of radon in workplace could be regarded as the responsibility of the operating management and should be considered as occupational exposure. In developed caves in which guides provide tours for the general public great care is needed for taking remedial actions concerning radon, because in some circumstances forced ventilation may alter the humidity inside the cave affecting the some of the formations or paintings that attract tourists. Tourist guides can work about 1900 hours per year, so the only option to protect them and other cave workers from radon exposure is to apply an appropriate system of radiation protection mainly based on limitation of exposure by restricting the amount of time spent in the cave. The information needed for carrying out the above mentioned protecting actions is related with the specific characteristics of the cave concerning the behaviour of radon and it decay products. In order to perform a precise effective dose calculation, factors like unattached progeny fraction (fp), equilibrium factor (F) and particle concentration (Z) are of main importance. One of the specific characteristic of the caves is the high unattached fraction due to very low particle concentration. The fp values can be higher than 0.1, for places with low ventilation and without additional aerosol sources, with Z -3 .In this work the results of the first stage of

  19. Analysis of the main factors affecting the evaluation of the dose in workplaces: the case of tourist caves

    Energy Technology Data Exchange (ETDEWEB)

    Sainz, C.; Santiago Quindos, L.; Fuente, I.; Nicolas, J.; Quindos, L. [Cantabria Univ., Dept. of Medical Physics. RADON Group, Faculty of Medicine, (Spain)

    2006-07-01

    Since 2001, Spanish law incorporated EURATOM basic standards for radiological protection, which include a request at the European Communities Member States to determine the working places on which exposure to natural radiation is significant. On Title VII (BOE 178/2001) radiation coming from natural sources has analogous role than radiation emitted from artificial ones used to. High concentrations of radon exist in several workplaces like tourist caves mainly because of the low ventilation rates existing at these enclosures. In this sense, in its 1990 publication, the ICRP recommended that high exposures of radon in workplace could be regarded as the responsibility of the operating management and should be considered as occupational exposure. In developed caves in which guides provide tours for the general public great care is needed for taking remedial actions concerning radon, because in some circumstances forced ventilation may alter the humidity inside the cave affecting the some of the formations or paintings that attract tourists. Tourist guides can work about 1900 hours per year, so the only option to protect them and other cave workers from radon exposure is to apply an appropriate system of radiation protection mainly based on limitation of exposure by restricting the amount of time spent in the cave. The information needed for carrying out the above mentioned protecting actions is related with the specific characteristics of the cave concerning the behaviour of radon and it decay products. In order to perform a precise effective dose calculation, factors like unattached progeny fraction (fp), equilibrium factor (F) and particle concentration (Z) are of main importance. One of the specific characteristic of the caves is the high unattached fraction due to very low particle concentration. The fp values can be higher than 0.1, for places with low ventilation and without additional aerosol sources, with Z < 4 103 particle cm{sup -3}.In this work the results

  20. A new approach to evaluate factors controlling elemental sediment–seawater distribution coefficients (K{sub d}) in coastal regions, Japan

    Energy Technology Data Exchange (ETDEWEB)

    Takata, Hyoe, E-mail: takata@kaiseiken.or.jp [Marine Ecology Research Institute, Central Laboratory, Onjuku, Chiba (Japan); National Institute of Radiological Sciences, Chiba City, Chiba (Japan); Aono, Tatsuo; Tagami, Keiko; Uchida, Shigeo [National Institute of Radiological Sciences, Chiba City, Chiba (Japan)

    2016-02-01

    In numerical models to simulate the dispersion of anthropogenic radionuclides in the marine environment, the sediment–seawater distribution coefficient (K{sub d}) for various elements is an important parameter. In coastal regions, K{sub d} values are largely dependent on hydrographic conditions and physicochemical characteristics of sediment. Here we report K{sub d} values for 36 elements (Na, Mg, Al, K, Ca, V, Mn, Fe, Co, Ni, Cu, Se, Rb, Sr, Y, Mo, Cd, I, Cs, rare earth elements, Pb, {sup 232}Th and {sup 238}U) in seawater and sediment samples from 19 Japanese coastal regions, and we examine the factors controlling the variability of these K{sub d} values by investigating their relationships to hydrographic conditions and sediment characteristics. There was large variability in K{sub d} values for Al, Mn, Fe, Co, Ni, Cu, Se, Cd, I, Pb and Th. Variations of K{sub d} for Al, Mn, Fe, Co, Pb and Th appear to be controlled by hydrographic conditions. Although K{sub d} values for Ni, Cu, Se, Cd and I depend mainly on grain size, organic matter content, and the concentrations of hydrous oxides/oxides of Fe and Mn in sediments, heterogeneity in the surface characteristics of sediment particles appears to hamper evaluation of the relative importance of these factors. Thus, we report a new approach to evaluate the factors contributing to variability in K{sub d} for an element. By this approach, we concluded that the K{sub d} values for Cu, Se, Cd and I are controlled by grain size and organic matter in sediments, and the K{sub d} value for Ni is dependent on grain size and on hydrous oxides/oxides of Fe and Mn. - Highlights: • K{sub d}s for 36 elements were determined in 19 Japanese coastal regions. • K{sub d}s for several elements appeared to be controlled by multiple factors in sediments. • We evaluated these factors based on physico-chemical characteristics of sediments.

  1. Closed-loop control with a coupling factor using an AO system

    International Nuclear Information System (INIS)

    Seo, Y-S; Baik, S-H; Park, S-K; Hong, S-K; Lim, C; Kim, C-J

    2008-01-01

    To stabilize a closed-loop control for a wavefront correction of a distorted laser beam, the instrumentation of an adaptive optics system and the closed-loop wavefront correction algorithms were investigated. We proposed a new control algorithm using a coupling factor from the zonal and the modal ideas. Compensating for an arbitrary wavefront distortion of a laser beam in the real-time, the wavefront correction speed was 5 Hz using the proposed methods of a zonal control with a coupling factor. Although the correction speed is slower in the new algorithm, the correction accuracy is more stable. The experimental results show that the proposed algorithm is appropriate for the wavefront correction of a low frequency fluctuation

  2. Research progress on influencing factors of hospital infection and prevention and control measures

    Directory of Open Access Journals (Sweden)

    He Wenlong

    2015-03-01

    Full Text Available Hospital infections are associated with the emergence of hospitals. As the understanding of hospital infections deepen and prevention and control measures improve, hospital infections have become manageable. In recent years, affected by the increase in invasive treatment technology, antimicrobial abuse, and other factors, the control of hospital infection has encountered new problems. This paper reviews the influencing factors of hospital infections and their prevention and control measures.

  3. Approaches for the integration of human factors into the upgrading and refurbishment of control rooms - Summary and conclusions - Principal Working Group 1 on Operating Experience and Human Factors

    International Nuclear Information System (INIS)

    2002-01-01

    a broad range of interested parties, in relation to the upgrading and refurbishing of control rooms. The workshop attracted 16 contributions from 13 different countries and provided a range of insights and lessons based on design experience, practical experience, research and regulatory needs, and an opportunity for the exchange of experiences and approaches on a range of important topics. The workshop also sought to identify and prioritize areas meriting further consideration and research. The 34 participants shared their experiences and perceptions on a broad number of aspects including: - The identification of human factors issues from the utility, vendor, and regulatory perspectives. - Ensuring the inclusion and implementation of human factors issues within the upgrade or refurbishment process. - How this change process should be managed. - Feedback from practical experience and real concerns. - Meeting modern human factors requirements. This report presents a summary of the conclusions and recommendations from the workshop. five main points were considered by the participants in the workshop as important areas for future work or research: - There is a need to collate a 'lessons learnt' database relating to human factors and control room upgrades; - There is a need to co-ordinate the method/tool development and use in order to better support evaluations and comparisons; - there is a need to show how to establish a performance baseline before change in order to demonstrate that performance is at least as good, or better, that prior to the change; - It is important to support the use of a 'control room philosophy' prior to, during, and after the upgrade; - There is a need to have a better-shared understanding of the design process and how the different disciplines involved contribute to it

  4. Operations strategy for workload balancing of crews in an advanced main control room

    International Nuclear Information System (INIS)

    Kim, Seunghwan; Kim, Yochan; Jung, Wondea

    2016-01-01

    The advanced main control room (advanced-MCR) is the one that allows for reactor operations based on digital instrumentation and control (I and C) technology. Thus, the operators of an advanced-MCR operate the plant through digital I and C interfaces, and for this purpose, an additional digital manipulation task for the operating equipment should be performed that cannot be observed in a conventional-MCR. As a prior study proposing the cognitive, communicative, and operational activity measurement approach (COCOA), COCOA enables an evaluation of the operator's workload in an advanced-MCR,which includes newly generated tasks for Man-Machine Interface System based secondary operation under a digital environment, which does not exist in a conventional-MCR. As a result of observations on the workload level by utilizing COCOA for a reference plant with an advanced-MCR when conducting an emergency operating procedure, it was observed that the workload of the shift supervisor is about two times greater than that of other operators. This is because operators therein stuck to the old guidelines customized to a conventional-MCR and failed to accomplish load balancing in consideration of the operation environment that an advanced-MCR provides. In this context, it would be imperative to develop and apply an operations strategy for an advanced-MCR operation. This study proposes an operations strategy in an attempt to make a balanced workload of operators in an advanced-MCR. (author)

  5. Trade practices are main factors involved in the transmission of viral haemorrhagic septicaemia

    DEFF Research Database (Denmark)

    Reichert, M.; Matras, M.; Skall, Helle Frank

    2013-01-01

    subgroups. The main source of outbreaks in European rainbow trout farming is sublineage Ia isolates. Recently, this group of isolates has been further subdivided in to two subclades of which the Ia-2 consists of isolates occurring mainly in Continental Europe outside of Denmark. In this study, we sequenced...... the full-length G-gene sequences of 24 VHSV isolates that caused VHS outbreaks in Polish trout farms between 2005 and 2009. All these isolates were identified as genotype Ia-2; they divided however into two genetically distinct subgroups, that we name Pol I and Pol II. The Pol I isolates mainly caused...... cause of virus transmission appears to be movement of fish. At least in Polish circumstances trading practices appear to have significant impact on spreading of VHSV infection....

  6. Human factors inspection of current control room panel in Jose Cabrera NPP

    International Nuclear Information System (INIS)

    Almeida, P.; O'Hara, J.; Higgins, J.

    2002-01-01

    Within the process of renewal of Exploitation Permit of Jose Cabrera Nuclear Power Plant, UNION FENOSA GENERACIO, S. A. (UFG) has carried out an analysis and evaluation project regarding human factors implications of current control room panel arrangement. The project has been developed in two phases. In the first phase, leaded by EPRI and carried out by experts from SAIC, an independent review from a double viewpoint of human reliability and human factors was developed. In the second phase, a multidisciplinary team (composed by human factors, risk analysis, operation, engineering, training and instrumentation and controls experts) has developed a study on human factors implications of current panel arrangement, following the methodology pointed out in NUREG-0711. The project has been developed under the direction of Brookhaven National Laboratory (BNL), organisation that has authored the aforementioned methodology, with the participation of UFG and SOLUZIONA Ingenieria. For the development of the second study the following steps were taken: Firstly, the potential effects of panel arrangement on crew performance were identified its real evidence was analysed and the goals for the improvement of control room operation were established; following NUREG-0711. After this, several design alternatives that addressed these goals were identified and were analysed along three dimensions: human factors, risk analysis and economic costs. Finally the results of these evaluations were combined using a multi-attribute decision method to arrive at a recommended alternative as he best proposal to incorporate human factors criteria and good practices in the design of control room panels. (Author)

  7. New multi-microprocessor control system of the main ring magnet power supply for the KEK 12 GeV PS

    International Nuclear Information System (INIS)

    Matsumoto, S.; Sueno, T.; Mikawa, K.; Toda, M.; Baba, H.

    1987-01-01

    The new control computer system has been installed at the last June. The main cpu supervised by the Unix covers man-machine interfacing and correction of current deviation in periodic control algorithm. The two sub-cpu are linked by a LAN and supported by a real time multi-task monitor. The one as the output process controller distributes 15 control patterns to 16-bit D/A converters at every 1.67 ms synchronized 6 phase ac line. The other as the input logs B Qf and Qd magnet current and voltage by 7 sets of 16-bit ADC at the same clock. Resulting precision of the currents from beam injection to flat top would be estimated at about a resolution limit of ADC except for current ripple. Ripple currents estimated at several times of an intrinsic ripple in the DCCT

  8. Aspects of control measures in occupational hygiene

    NARCIS (Netherlands)

    Lumens, M.

    1997-01-01


    This thesis focuses on two aspects which are of major importance in the broad field of control measures in occupational hygiene: the selection of control measures in a structured way and the impact of factors modifying the effectiveness of these control measures.

    The main

  9. CONTROLLING FACTORS OF POTENTIAL EVAPOTRANSPIRATION ABOVE GRASSLAND IN HUMID AND ARID AREA

    Directory of Open Access Journals (Sweden)

    . Yanto

    2013-05-01

    Full Text Available Potential evapotranspiration (PET is an importance process in water balance studies controlled by a number of meteorological factors such as temperature, wind speed, atmospheric pressure, solar radiation, vapor pressure gradient, relative humidity and biological factors such as vegetation type, canopy height and plant density that varied in time-scale and in spatial scale. Of all those variables, determining the most controlling factors of evapotranspiration in humid and arid area is of interest of this paper. Two sites representing humid and arid area i.e. Fermi Prairie site in Illinois and Audubon Research Ranch in Arizona respectively were investigated in this study.  The flux data employed in this study was acquired from Ameriflux Netwotk. Penmann-Monteith formula is employed in to estimate evapotranspiration rate in both sites. The result shows that the PET is in dependence on the considered meteorological factor such as shortwave radiation, vapor pressure, air temperature, wind speed, net radiation and vapor pressure deficit. It is also can be inferred from the analysis that PET is also strongly controlled by vegetation factors represented as stomatal resistance. Keywords: Potential evapotranspiration, Penmann-Monteith, humid, arid.

  10. Ranking malaria risk factors to guide malaria control efforts in African highlands.

    Directory of Open Access Journals (Sweden)

    Natacha Protopopoff

    Full Text Available INTRODUCTION: Malaria is re-emerging in most of the African highlands exposing the non immune population to deadly epidemics. A better understanding of the factors impacting transmission in the highlands is crucial to improve well targeted malaria control strategies. METHODS AND FINDINGS: A conceptual model of potential malaria risk factors in the highlands was built based on the available literature. Furthermore, the relative importance of these factors on malaria can be estimated through "classification and regression trees", an unexploited statistical method in the malaria field. This CART method was used to analyse the malaria risk factors in the Burundi highlands. The results showed that Anopheles density was the best predictor for high malaria prevalence. Then lower rainfall, no vector control, higher minimum temperature and houses near breeding sites were associated by order of importance to higher Anopheles density. CONCLUSIONS: In Burundi highlands monitoring Anopheles densities when rainfall is low may be able to predict epidemics. The conceptual model combined with the CART analysis is a decision support tool that could provide an important contribution toward the prevention and control of malaria by identifying major risk factors.

  11. Analysis of Communication between Main Control Room Operators in Decision-making Process in Steam Generator Tube Rupture Accident

    International Nuclear Information System (INIS)

    Petkov, M.; Petkov, G.

    2006-01-01

    The paper presents an investigation results for Main Control Room operators' reliability by Performance Evaluation of Teamwork method, based on FSS-1000 training archives in KNPP in case of Steam Generator Tube Rupture accident. The advantages of operators' teamwork are shown: a) group decision-making vs. individual one: b) positive influence of crew initiated communication consisting of orders and reports that are required by instruction. (authors)

  12. Assessing risk factors in the organic control system: evidence from inspection data in Italy.

    Science.gov (United States)

    Zanoli, Raffaele; Gambelli, Danilo; Solfanelli, Francesco

    2014-12-01

    Certification is an essential feature in organic farming, and it is based on inspections to verify compliance with respect to European Council Regulation-EC Reg. No 834/2007. A risk-based approach to noncompliance that alerts the control bodies to activate planning inspections would contribute to a more efficient and cost-effective certification system. An analysis of factors that can affect the probability of noncompliance in organic farming has thus been developed. This article examines the application of zero-inflated count data models to farm-level panel data from inspection results and sanctions obtained from the Ethical and Environmental Certification Institute, one of the main control bodies in Italy. We tested many a priori hypotheses related to the risk of noncompliance. We find evidence of an important role for past noncompliant behavior in predicting future noncompliance, while farm size and the occurrence of livestock also have roles in an increased probability of noncompliance. We conclude the article proposing that an efficient risk-based inspection system should be designed, weighting up the known probability of occurrence of a given noncompliance according to the severity of its impact. © 2014 Society for Risk Analysis.

  13. [Case-control study of risk factors associated with constipation. The FREI Study].

    Science.gov (United States)

    Comas Vives, A; Polanco Allué, I

    2005-04-01

    Children represent one of the patient groups most affected by constipation. Our objective was to identify and describe the risk factors associated with childhood constipation. The study had a case-control, retrospective, open and multicenter design. Clinical data on possible risk factors were collected through an ad-hoc questionnaire. Two groups were studied: children with and without constipation. Nine hundred twenty-one children were recruited; of these, 898 (97.6%) were included in the statistical analysis. There were 408 (45.4%) children in the constipated group and 490 (54.5%) in the non-constipated group. Most of the children with constipation (53.6%) had a maternal history of constipation compared with 21.4% of children without constipation (p constipated children reported a lack of regularity in their toilet habits while 64.9 % of the children without constipation went to the toilet regularly. Toilet training started slightly earlier (at 3 years) in children without constipation (93.2%) than in those with the disorder (83.8%) (p constipation never used the toilet compared with 26.8% of those without constipation (p constipation drank less than four glasses of water per day compared with 47.1% of those without constipation (p constipation than in those without (p constipation found in this study were a familial history of constipation, irregular toilet habits, low dietary fiber contents and no fruit intake. The main preventive factors against constipation were water and vegetable consumption and training on the use of the toilet at school. Daily toilet training and dietary changes are needed to prevent constipation among children and to achieve regular defecation. This preventive intervention should be reinforced at school.

  14. State of oral hygiene and identification of the main risk factors for inflammatory diseases of periodontal tissues in young people.

    OpenAIRE

    Makarenko, M. V.

    2014-01-01

    A high percentage of prevalence of inflammatory periodontal diseases in young age causes urgency of treatment and prevention of inflammatory diseases of periodontal tissue in young age. Therefore, the research purpose was to investigate the hygienic condition and identification of the main risk factors for gingivitis in patients aged 18-30 years. 286 people aged from 18 to 30 years were observed in the study. To assess hygienic condition of the oral cavity and to determine the thickness of pl...

  15. Risk Factors For Ectopic Pregnancy : A Case Control Study

    Directory of Open Access Journals (Sweden)

    Deshmukh J.S

    1999-01-01

    Full Text Available Research question: Which are the risk factors for ectopic pregnancy . Objective: To study the strength of association between hypothesised risk factors and ectopic pregnancy. Study design: Unmatched case- control study. Setting: Government Medical College, Hospital, Nagpur. Participants: 133 cases of ectopic pregnancy and equal number of controls (non pregnant women admitted to study hospital. Study variables : Pelvic inflammatory diseases, sexually transmitted diseases, IUD use at conception , past use of IUD, prior ectopic pregnancy, OC pills use at the time of conception, past use of OC pills, induced abortion, spontaneous abortion, infertility and pelvic and abdominal surgery. Statistical analysis: Odds ratios & their 95% CI, Pearson’s chi square test, unconditional logistic regression analysis and population attributable risk proportion. Results : Use of IUD at conception, prior ectopic pregnancy , pelvic inflammatory disease, sexually transmitted diseases, infertility, OC pills use at the time of conception, past use of IUD and induced abortion were found to be significantly associated with ectopic pregnancy. Conclusion: Identification of these risk factors for etopic pregnancy shall help in early detection and appropriate management in an individual case and it may help in devising a comprehensive preventive strategy for ectopic pregnancy

  16. Occupational risk factors for testicular cancer: a registry-based case-control study in Rhineland Palatinate – Germany

    Science.gov (United States)

    Yousif, Lamyaa; Hammer, Gaël P.; Emrich, Katharina; Blettner, Maria; Zeeb, Hajo

    2013-01-01

    Objectives: Testicular cancer affects mainly men below the age of 50. An association with occupation and social status has been suggested but risk factors are not well understood. A registry-based case-control study focusing on occupation was performed in Germany. Methods: All 348 testicular cancer cases with available gainful occupational information registered between 2000 and 2005; as well as 564 suitable controls (from a pool of other cancers) were drawn from the Cancer Registry of Rhineland-Palatinate. Unconditional logistic regression was used to compute odds ratios (OR) and associated 95% confidence intervals (CI). Results: Slightly elevated OR were observed for technicians and related professionals (OR 1.62, 95% CI 1.00–2.63) and for clerical support workers (OR 1.71, 95% CI 1.14–2.56). This increase was highest in the age group 20–50 for technicians (OR 2.02, 95% CI 1.23–3.33) and clerks (OR 2.00, 95% CI 1.30–3.09), respectively. An association with testicular cancer was observed for no other occupation. Conclusion: An increased risk of testicular cancer was observed for technicians and related professionals and clerical support workers. This could be related to socioeconomic status or sedentary life style, two factors that were identified in previous studies. While the feasibility of a purely registry-based study was shown, missing occupational data and the choice of cancer controls represent challenges to the validity of this approach. PMID:24265602

  17. Enhancing the NCSU PULSTAR reactor control room with human factors considerations

    International Nuclear Information System (INIS)

    Glover, B.L.; Pupons, D.E.; Perez, P.B.

    1993-01-01

    The North Carolina PULSTAR research reactor was constructed to support teaching, training, and research. The training provided is not limited to academic students but encompasses plant operators, managers, engineers, designers, and supporting organizations in the nuclear industry. Our facility is under-going design changes to maximize teaching effectiveness and continued safe operation by providing current technology in the control room. The opportunity for the enhancements is a result of the generosity of neighboring utilities and the US Department of Energy instrumentation upgrade funds. Our objective, to provide a control room environment that conforms to selected industry practices, required human factors input. A human factors course, offered jointly between the industrial engineering and the psychology departments, included the PULSTAR control room enhancement as a case study

  18. 14 CFR 23.533 - Hull and main float bottom pressures.

    Science.gov (United States)

    2010-01-01

    ... 14 Aeronautics and Space 1 2010-01-01 2010-01-01 false Hull and main float bottom pressures. 23... Water Loads § 23.533 Hull and main float bottom pressures. (a) General. The hull and main float....00213; K2=hull station weighing factor, in accordance with figure 2 of appendix I of this part; VS1...

  19. Fatores associados à recorrência da gravidez na adolescência em uma maternidade escola: estudo caso-controle Factores asociados con la recurrencia de embarazos de adolescentes en una maternidad escuela: estudio de casos y controles A case-control study of factors associated with repeat teen pregnancy based on a sample from a university maternity hospital

    Directory of Open Access Journals (Sweden)

    Leila Katz

    2013-03-01

    Full Text Available Recorrência da gravidez na adolescência é uma situação frequente, sendo considerada como um fator agravante tanto para o aumento da morbidade materna e fetal quanto para aumento de problemas sociais. O objetivo desta pesquisa foi identificar fatores associados à recorrência de gravidez em adolescentes. Realizou-se estudo caso-controle com puérperas, incluindo 90 adolescentes com mais de uma gravidez (caso e 90 adultas, mulheres que tiveram uma gestação na adolescência, mas que não recorreram (controle. Para análise estatística, utilizou-se regressão logística hierarquizada, com nível de significância de 5%. Os fatores que permaneceram associados à recorrência da gravidez na adolescência foram: coitarca La recurrencia del embarazo en la adolescencia es una situación frecuente, siendo considerada como un factor agravante, tanto para el aumento de la morbilidad materna y fetal, como para el aumento de problemas sociales. El objetivo de esta investigación fue identificar factores asociados a la recurrencia de embarazo en adolescentes. Se realizó un estudio de caso-control con puérperas, incluyendo 90 adolescentes con más de un embarazo (caso y 90 adultas, mujeres que tuvieron una gestación en la adolescencia, pero que no recurrieron (control. Para el análisis estadístico, se utilizó la regresión logística jerarquizada, con un nivel de significancia de un 5%. Los factores que permanecieron asociados a la recurrencia de embarazo en la adolescencia fueron: coitarca Repeat teen pregnancy is a frequent issue and is considered an aggravating factor for increased maternal and fetal morbidity and social problems. The aim of the study was to identify factors associated with repeat teen pregnancy. A case-control study was conducted in 90 postpartum adolescents with more than one pregnancy (cases and 90 adult women with a history of only one pregnancy during adolescence (controls. Statistical analysis used hierarchical logistic

  20. Factors associated with good TB infection control practices among primary healthcare workers in the Free State Province, South Africa.

    Science.gov (United States)

    Engelbrecht, Michelle; Janse van Rensburg, André; Kigozi, Gladys; van Rensburg, Hcj Dingie

    2016-11-04

    Despite the availability of TB infection control guidelines, and good levels of healthcare worker knowledge about infection control, often these measures are not well implemented. This study sought to determine the factors associated with healthcare workers' good TB infection control practices in primary health care facilities in the Free State Province, South Africa. A cross-sectional self-administered survey among nurses (n = 202) and facility-based community healthcare workers (n = 34) as well as facility observations were undertaken at all 41 primary health care facilities in a selected district of the Free State Province. The majority of respondents were female (n = 200; 87.7 %) and the average age was 44.19 years (standard deviation ±10.82). Good levels of knowledge were recorded, with 42.8 % (n = 101) having an average score (i.e. 65-79 %) and 31.8 % (n = 75) a good score (i.e. ≥ 80 %). Most respondents (n = 189; 80.4 %) had positive attitudes towards TB infection control practices (i.e. ≥ 80 %). While good TB infection control practices were reported by 72.9 % (n = 161) of the respondents (i.e. ≥75 %), observations revealed this to not necessarily be the case. For every unit increase in attitudes, good practices increased 1.090 times (CI:1.016-1.169). Respondents with high levels of knowledge (≥80 %) were 4.029 (CI: 1.550-10.469) times more likely to have good practices when compared to respondents with poor levels of knowledge (control were the main factors associated with good infection control practices. Although many respondents reported good infection control practices - which was somewhat countered by the observations - there are areas that require attention, particularly those related to administrative controls and the use of personal protective equipment.

  1. Therapeutic interventions and success in risk factor control for secondary prevention of stroke.

    Science.gov (United States)

    Alvarez-Sabin, Jose; Quintana, Manuel; Hernandez-Presa, Miguel Angel; Alvarez, Carlos; Chaves, Jose; Ribo, Marc

    2009-01-01

    We sought to evaluate the success rates in achieving preventive therapeutic goals in patients who experienced an ischemic stroke (IS) and compare them with those achieved in patients with coronary artery disease (CAD). This was an observational multicenter case-control study (3 patients with IS and one control subject with CAD) performed in 1444 primary health centers in Spain. Preventive therapeutic objectives according to American Heart Association guidelines were predefined. Demographic data, vascular risk factors, and success/failure in achievement of objectives were recorded and compared between patients with IS and CAD. A total of 5458 patients were included, 4098 (75.1%) had IS and 1360 (24.9%) had CAD. Although more than 90% of patients with hypertension, diabetes, or dyslipidemia were under specific drug regimens, only about 25% achieved the recommended therapeutic objective for each risk factor. Success rate was especially low among patients with IS compared with CAD: hypertension (23.8% v 27.2%; P = .028); dyslipidemia (13.6% v 20.3%; P risk factors under control, compared with 5.6% of those with CAD (P = .006). For all patients, multivariate logistic regression model showed that independent predictors of full risk factor control were: presence of CAD as compared with IS (odds ratio [OR] 2.11; 95% confidence interval [CI] 1.35-3.29; P = .001), older age (OR 1.02; 95% CI 1.00-1.04; P = .028), and having less than 3 risk factors (OR 16.98; 95% CI 9.02-31.97; P risk factor control.

  2. Development of task analysis method for operator tasks in main control room of an advanced nuclear power plant

    International Nuclear Information System (INIS)

    Lin Chiuhsiangloe; Hsieh Tsungling

    2016-01-01

    Task analysis methods provide an insight for quantitative and qualitative predictions of how people will use a proposed system, though the different versions have different emphases. Most of the methods can attest to the coverage of the functionality of a system and all provide estimates of task performance time. However, most of the tasks that operators deal with in a digital work environment in the main control room of an advanced nuclear power plant require high mental activity. Such mental tasks overlap and must be dealt with at the same time; most of them can be assumed to be highly parallel in nature. Therefore, the primary aim to be addressed in this paper was to develop a method that adopts CPM-GOMS (cognitive perceptual motor-goals operators methods selection rules) as the basic pattern of mental task analysis for the advanced main control room. A within-subjects experiment design was used to examine the validity of the modified CPM-GOMS. Thirty participants participated in two task types, which included high- and low-compatibility types. The results indicated that the performance was significantly higher on the high-compatibility task type than on the low-compatibility task type; that is, the modified CPM-GOMS could distinguish the difference between high- and low-compatibility mental tasks. (author)

  3. Impact of therapeutic factors on local control in T2-T3 anal carcinoma treated by radiation or radiochemotherapy

    International Nuclear Information System (INIS)

    Allal, Abdelkarim S.; Mermillod, Bernadette; Kurtz, John M.; Marti, Marc-Claude

    1996-01-01

    Purpose: To investigate the influence of therapeutic parameters on local control in T2-T3 anal carcinoma treated by chemo-radiotherapy or radiation therapy alone. Materials and Methods: From 1976 to 1993, 137 patients with anal carcinoma staged T2 (85) or T3 (52) completed curative sphincter-conservating treatment, 54 with radiotherapy alone and 83 with concomitant chemo-radiotherapy. Radiation therapy was delivered in two sequences with a median gap of 46 days. The two main techniques used for the first sequence were a direct perineal cobalt field ± a sacral arc field with a median dose of 30 Gy/10 fractions/19 days (27.7%) and two antero-posterior opposed pelvic fields (≥ 6 MV photons) with a median dose of 40 Gy/20 fractions/31 days (62%). Iridium-192 implant boost was used in 116 patients (median dose 20 Gy, Paris system) and external radiation boost in 21 patients (median dose 20 Gy/10 fractions/13 days). Generally the chemoradiotherapy patients received starting on day 1 an IV bolus of Mitomycin-C (0.4 mg/kg, maximum 20 mg) and a 5-day continuous infusion of 5-fluorourcil 600-800 mg/m 2 /day. For surviving patients median follow-up was 65 months. Univariate and multivariate analyses were carried out to determine therapeutic parameters affecting local control after adjustment for clinical factors. Results: The 5-year actuarial local control was 77%. Factors associated with a decrease of local control in univariate analysis included: age less than 66 years (67% vs 85%), male gender (65% vs 81%), tumor extension more than (1(3)) circumference of the anal canal (68% vs 90%), lymph node involvement (64% vs 81%), use of external irradiation for the boost (62% vs 79%), and overall treatment time more than 74 days (69% vs 85%). In a multivariate analysis none of the therapeutic parameters remained significant when adjusted for the four significant clinical factors. The only therapeutic factor which might have had an impact was overall treatment time (p = .09

  4. Factors controlling contrail cirrus optical depth

    Directory of Open Access Journals (Sweden)

    B. Kärcher

    2009-08-01

    Full Text Available Aircraft contrails develop into contrail cirrus by depositional growth and sedimentation of ice particles and horizontal spreading due to wind shear. Factors controlling this development include temperature, ice supersaturation, thickness of ice-supersaturated layers, and vertical gradients in the horizontal wind field. An analytical microphysical cloud model is presented and validated that captures these processes. Many individual contrail cirrus are simulated that develop differently owing to the variability in the controlling factors, resulting in large samples of cloud properties that are statistically analyzed. Contrail cirrus development is studied over the first four hours past formation, similar to the ages of line-shaped contrails that were tracked in satellite imagery on regional scales. On these time scales, contrail cirrus optical depth and microphysical variables exhibit a marked variability, expressed in terms of broad and skewed probability distribution functions. Simulated mean optical depths at a wavelength of 0.55 μm range from 0.05-0.5 and a substantial fraction 20-50% of contrail cirrus stay subvisible (optical depth <0.02, depending on meteorological conditions.

    A detailed analysis based on an observational case study over the continental USA suggests that previous satellite measurements of line-shaped persistent contrails have missed about 89%, 50%, and 11% of contrails with optical depths 0-0.05, 0.05-0.1, and 0.1-0.2, respectively, amounting to 65% of contrail coverage of all optical depths. When comparing observations with simulations and when estimating the contrail cirrus climate impact, not only mean values but also the variability in optical depth and microphysical properties need to be considered.

  5. Multi-factor controls on terrestrial carbon dynamics in urbanised areas

    Science.gov (United States)

    Zhang, C.; Tian, H.; Pan, S.; Lockaby, G.; Chappelka, A.

    2013-11-01

    As urban land cover and populations continue rapidly increasing across the globe, much concern has been raised that urbanization may significantly alter terrestrial carbon dynamics that affects atmospheric CO2 concentration and climate. Urbanization involves complex changes in land structure and multiple environmental factors. Relative contribution of these and their interactive effects need be quantified to better understand urbanization effects on regional C dynamics as well as assess the effectiveness of C sequestration policies focusing on urban green space development. In this study, we analyzed the factors that may control the urbanization effect on ecosystem C dynamics, and proposed a numeric experimental scheme, i.e. scenarios design, to conduct factorial analysis on the effects of different factors. Then as a case study, a dynamic land ecosystem model (DLEM) was applied to quantify the urbanization effect on the C dynamics of the Southern US (SUS) from 1945-2007, and to analyze the relative contributions from each environmental factor and their interactive effects. We found the effect of urban land conversion dominated the C dynamics in the SUS, resulting in about 0.37 Pg C lost from 1945-2007. However, urban ecosystem management and urban-induced environmental changes enhanced C sequestration by 0.12 Pg and 0.03 Pg, respectively. Their C sequestration effects, which amounted to 40% of the magnitude of land conversion effect, partially compensated for the C loss during urbanization. Numeric experiments and factorial analyses indicated complex interactive effects among different factors and between various land covers and environmental controls, findings need to be further confirmed by field studies. The proposed numeric experimental scheme provides a quantitative approach for understanding the complex mechanisms controlling C dynamics, and defining best development practices in urbanised areas.

  6. Determinants of risk factor control in subjects with coronary heart disease : a report from the EUROASPIRE III investigators.

    LENUS (Irish Health Repository)

    Cooney, Marie Therese

    2012-04-18

    The EUROASPIRE audits of risk factor control have indicated that, even in those with established coronary heart disease, risk factor control remains poor. We therefore analysed the EUROASPRE III data set to establish the factors associated with success or failure in risk factor control in order to inform future risk factor management strategies. University education, attendance at a specialist cardiology clinic, and participation in a cardiac rehabilitation programme were associated with improved risk factor control. Risk factor control was poorer in women, those with diabetes, and those undergoing coronary artery bypass surgery as opposed to medical therapy or percutaneous coronary intervention. Increasing age, depression, and anxiety were not associated with poorer risk factor control.

  7. Fatores de risco para óbitos neonatais no Recife: um estudo caso-controle Risk factors for neonatal death in Recife: a case-control study

    Directory of Open Access Journals (Sweden)

    Sílvia W. Sarinho

    2001-08-01

    Full Text Available OBJETIVOS: a mortalidade neonatal é o componente mais importante da mortalidade infantil na cidade do Recife. Este estudo teve como objetivo determinar os principais fatores de risco para morte neonatal no município do Recife em 1995. MÉTODOS: o desenho do estudo foi do tipo caso-controle. Realizou-se a validação dos bancos de dados do Sistema de Informação em Mortalidade e Sistema de Informação Nascido Vivo, para mães residentes no Recife, no ano de 1995. Obteve-se, após técnica do linkage entre os dois bancos de dados, amostra com 456 casos e 2.280 controles. Como medida de risco utilizou-se Odds Ratio, com intervalo de confiança de 95% e para a diferença de proporção, o teste qui quadrado. Utilizou-se na análise multivariada a técnica da regressão logística. RESULTADOS: verificou-se que 358 (79,7% das crianças que evoluíram para óbito foram de baixo peso ao nascer, com risco de morte 46 vezes superior (IC=33,8-59,0 P 2.500g. Por ordem decrescente de valores da medida de associação de morte neonatal com as variáveis estudadas através da análise multivariada, os principais fatores de risco foram peso ao nascer OBJECTIVE: Neonatal mortality is the main cause of infant mortality in the city of Recife. The objective of the present study was to determine the major risk factors for neonatal death in Recife in 1995. METHODS: This is a case control study. Information was obtained from the mortality and live birth databases after validation of the data set, between January and December 1995. A sample of 456 cases and 2,280 controls was obtained after using the linkage technique between the two data sets. The difference in proportion was analyzed by the chi square test. The odds ratio was calculated as a risk measure, with a 95% confidence interval. The logistic regression technique was used to adjust potential confounding factors. RESULTS: 212 deaths (46.6% occurred in the first 24 hours of life. We found that 358 (79.7% of

  8. Body weight variation and control of cardiovascular risk factors in essential hypertension.

    Science.gov (United States)

    Pascual, Jose Maria; Rodilla, Enrique; Costa, Jose Antonio; Perez-Lahiguera, Francisco; Gonzalez, Carmen; Lurbe, Empar; Redón, Josep

    2009-01-01

    The objective was to assess the impact of weight changes on blood pressure (BP), lipids and glucose goals in a cohort of hypertensive subjects. Prospective follow-up. Hypertension clinic. 326 hypertensive non-diabetic subjects, 46% with metabolic syndrome (MS). Usual care treatment, which included diet, physical exercise and drugs prescribed when indicated. All patients were observed for up to 1 year. BP and low-density lipoprotein-cholesterol (LDL-C) goal were those in ESH/ESC and ATP III recommendations, respectively. The glucose goal was to delay progression to type 2 diabetes mellitus, or to achieve blood glucose <100 mg/dl for non-diabetics. According to body weight changes, patients were categorized using adjusted ROC curves models. Overall, there was a significant weight increment of 0.5 kg (95% CI 0.1-0.9 kg); 28 patients (8.6%) lost more than 5 kg, and only four (1.2%) lost more than 10 kg. BP, LDL-C and glucose goals were achieved in 56%, 78% and 61% of patients, respectively. To lose or not gain weight was an independent prognostic factor to achieve the BP goal in all the patients and the LDL goal in the presence of MS. For glucose control, being treated with beta-blockers and/or diuretics was a negative factor. In hypertensive subjects, even small changes in weight may have an important impact on achieving cardiovascular goals, mainly in those with MS.

  9. Ergonomic design of mosaic control panel and standardised control tile configurations for 500 MWe PHWR

    International Nuclear Information System (INIS)

    Ughade, A.V.; Das, R.N.; Ramakrishnan, S.

    1994-01-01

    A review of control rooms of operating nuclear power plants identified many design problems having potential for degrading the performance of operators. Many indications and controls on existing control panels are placed outside the recommended visual and reach envelopes for acceptable operator usage. As a result, the application of human factor principles was found to be needed. This paper describes the design approach for working out the dimensions of main control room panels and console using human engineering principles and recommends the ergonomic dimensions of the main control room panels and console. Further it gives the basis and works out the control tile configurations for 500 MWe PHWR project. It also suggests the use of a full scale mock up for design evaluation and verification. (author). 7 refs., 4 figs

  10. Risk Factors of Rheumatic Heart Disease in Bangladesh: A Case-Control Study

    Science.gov (United States)

    Riaz, Baizid Khoorshid; Karim, Md. Nazmul; Chowdhury, Kamrun Nahar; Chowdhury, Shahabul Huda; Rahman, Md. Ridwanur

    2013-01-01

    Not all cases of rheumatic fever (RF) end up as rheumatic heart disease (RHD). The fact raises the possibility of existence of a subgroup with characteristics that prevent RF patients from developing the RHD. The present study aimed at exploring the risk factors among patients with RHD. The study assessed the risk of RHD among people both with and without RF. In total, 103 consecutive RHD patients were recruited as cases who reported to the National Centre for Control of Rheumatic Fever and Heart Disease, Dhaka, Bangladesh. Of 309 controls, 103 were RF patients selected from the same centre, and the remaining 206 controls were selected from Shaheed Suhrawardy Medical College Hospital, who got admitted for other non-cardiac ailments. RHD was confirmed by auscultation and colour Doppler echocardiography. RF was diagnosed based on the modified Jones criteria. An unadjusted odds ratio was generated for each variable, with 95% confidence interval (CI), and only significant factors were considered candidate for multivariate analysis. Three separate binary logistic regression models were generated to assess the risk factors of RF, risk factors of RHD compared to non-rheumatic control patients, and risk factors of RHD compared to control with RF. RF and RHD shared almost a similar set of risk factors in the population. In general, age over 19 years was found to be protective of RF; however, age of the majority (62.1%) of the RHD cases was over 19 years. Women [odds ratio (OR)=2.2, 95% CI 1.1-4.3], urban resident (OR=3.1, 95% CI 1.2–8.4), dwellers in brick-built house (OR=3.6, 95% CI 1.6-8.1), having >2 siblings (OR=3.1, 95% CI 1.5- 6.3), offspring of working mothers (OR=7.6, 95% CI 2.0-24.2), illiterate mother (OR=2.6, 95% CI 1.2-5.8), and those who did not brush after taking meals (OR=2.5, 95% CI 1.0-6.3) were more likely to develop RF. However, more than 5 members in a family showed a reduced risk of RF. RHD shared almost a similar set of factors in general. More than

  11. Electron Flux Dropouts at L ˜ 4.2 From Global Positioning System Satellites: Occurrences, Magnitudes, and Main Driving Factors

    Science.gov (United States)

    Boynton, R. J.; Mourenas, D.; Balikhin, M. A.

    2017-11-01

    Dropouts in electron fluxes at L ˜ 4.2 were investigated for a broad range of energies from 120 keV to 10 MeV, using 16 years of electron flux data from Combined X-ray Dosimeter on board Global Positioning System (GPS) satellites. Dropouts were defined as flux decreases by at least a factor 4 in 12 h, or 24 h during which a decrease by at least a factor of 1.5 must occur during each 12 h time bin. Such fast and strong dropouts were automatically identified from the GPS electron flux data and statistics of dropout magnitudes, and occurrences were compiled as a function of electron energy. Moreover, the Error Reduction Ratio analysis was employed to search for nonlinear relationships between electron flux dropouts and various solar wind and geomagnetic activity indices, in order to identify potential external causes of dropouts. At L ˜ 4.2, the main driving factor for the more numerous and stronger 1-10 MeV electron dropouts turns out to be the southward interplanetary magnetic field Bs, suggesting an important effect from precipitation loss due to combined electromagnetic ion cyclotron and whistler mode waves in a significant fraction of these events, supplementing magnetopause shadowing and outward radial diffusion which are also effective at lower energies.

  12. Structure of the main control system for the FTU device

    International Nuclear Information System (INIS)

    Panaccione, L.

    1983-01-01

    The computer based control system for FTU (Frascati Tokamak Upgrade) machine is a distributed intelligence control system consisting of various subsystems, called ''specific units''. A specific unit can work as a stand-alone small system or as a part of more complex systems, together with other units, in any possible combination. In the case of combined units working mode, a dedicated specific unit performs supervisory functions. Communication between specific units is done on a dedicated bus-like network, in the form of temporary master-slave relationship. There are three groups of specific units: Plant Control Units, Supervisory Control Unit and Synoptic Handling Unit. Performances and structures of these specific units are described. In addition, a very simple hard-wired safety system works in parallel with the computer based control system, in order to save personnel and apparatus. (author)

  13. Performance related factors are the main determinants of the von Willebrand factor response to exhaustive physical exercise

    NARCIS (Netherlands)

    J.E. van Loon (Janine ); M.A.H. Sonneveld (Michelle); S.F.E. Praet (Stephan); M.P.M. de Maat (Moniek); F.W.G. Leebeek (Frank)

    2014-01-01

    textabstractBackground: Physical stress triggers the endothelium to release von Willebrand Factor (VWF) from the Weibel Palade bodies. Since VWF is a risk factor for arterial thrombosis, it is of great interest to discover determinants of VWF response to physical stress. We aimed to determine the

  14. Human Factors and Data Fusion as Part of Control Systems Resilience

    Energy Technology Data Exchange (ETDEWEB)

    David I. Gertman

    2009-05-01

    Human performance and human decision making is counted upon as a crucial aspect of overall system resilience. Advanced control systems have the potential to provide operators and asset owners a wide range of data, deployed at different levels that can be used to support operator situation awareness. However, the sheer amount of data available can make it challenging for operators to assimilate information and respond appropriately. This paper reviews some of the challenges and issues associated with providing operators with actionable state awareness and argues for the over arching importance of integrating human factors as part of intelligent control systems design and implementation. It is argued that system resilience is improved by implementing human factors in operations and maintenance. This paper also introduces issues associated with resilience and data fusion and highlights areas in which human factors including field studies hold promise.

  15. TILLAGE EROSION: THE PRINCIPLES, CONTROLLING FACTORS AND MAIN IMPLICATIONS FOR FUTURE RESEARCH

    Directory of Open Access Journals (Sweden)

    Agnieszka Wysocka-Czubaszek

    2014-10-01

    Full Text Available Tillage erosion is one of the major contributors to landscape evolution in hummocky agricultural landscapes. This paper summarizes the available data describing tillage erosion caused by hand-held or other simple tillage implements as well as tools used in typical conventional agriculture in Europe and North America. Variations in equipment, tillage speed, depth and direction result in a wide range of soil translocation rates observed all over the world. The variety of tracers both physical and chemical gives a challenge to introduce the reliable model predicting tillage erosion, considering the number and type of tillage operation in the whole tillage sequence.

  16. Internet-based control recruitment for a case-control study of major risk factors for stroke in Korea: lessons from the experience.

    Science.gov (United States)

    Park, Jong-Moo; Cho, Yong-Jin; Lee, Kyung Bok; Park, Tai Hwan; Lee, Soo Joo; Han, Moon-Ku; Ko, Youngchai; Lee, Jun; Cha, Jae-Kwan; Lee, Byung-Chul; Yu, Kyung-Ho; Oh, Mi-Sun; Lee, Ji Sung; Lee, Juneyoung; Bae, Hee-Joon

    2014-01-01

    This study aimed to estimate the population-attributable risks (PARs) of 9 major risk factors for stroke in Korea through a case-control study and to test the feasibility and validity of internet-based control recruitment. From April 2008 to September 2009, controls were enrolled via internet after providing consent for participation through a web-based survey. The cases included patients who were admitted to the participating centers due to acute stroke or transient ischemic attack within 7 days of onset during the study period. Each control was age- and sex-matched with 2 cases. Adjusted odd ratios, age-standardized prevalence, and PARs were estimated for the 9 major risk factors using the prevalence of risk factors in the control group and the age and sex characteristics from Korea's national census data. In total, 1041 controls were matched to 2082 stroke cases. Because of a shortage of elderly controls in the internet-based recruitment, 248 controls were recruited off-line. The PARs were 23.44%, 10.95%, 51.32%, and 6.35% for hypertension, diabetes, smoking, and stroke history, respectively. Hypercholesterolemia, atrial fibrillation, obesity, coronary heart disease, and a family history of stroke were not associated with stroke. Comparison with education and religion of the control group with that mentioned in the national census data showed a notable difference. The study results imply that internet-based control recruitment for a case-control study requires careful selection of risk factors with high self-awareness and effective strategies to facilitate the recruitment of elderly participants. Copyright © 2014 National Stroke Association. Published by Elsevier Inc. All rights reserved.

  17. Maternal and neonatal risk factors for early-onset group B streptococcal disease: a case control study

    Directory of Open Access Journals (Sweden)

    Al-Kadri HM

    2013-10-01

    Full Text Available Hanan M Al-Kadri,1 Samira S Bamuhair,2 Sameera M Al Johani,3 Namsha A Al-Buriki,1 Hani M Tamim4 1Department of Obstetrics and Gynecology, 2Department of Basic Medical Sciences, 3Microbiology Division, 4Department of Medical Education, College of Medicine, King Saud Bin Abdulaziz University for Health Sciences, King Abdulaziz Medical City, Riyadh, Kingdom of Saudi Arabia Objectives: To identify the prominent maternal and neonatal risk factors associated with early-onset group B streptococcus (EOGBS disease in neonates and to determine their importance by comparing them with a control group. Setting: Neonatal unit at King Abdulaziz Medical City, Riyadh, Kingdom of Saudi Arabia. Patients: Cases were infants <7 days of age with invasive group B streptococcus (GBS disease diagnosed between January 1, 2000 and December 31, 2009. Controls were healthy infants born in the same hospital during the same period having the same birth weight and gestational age category. Main outcome measures: Maternal risk factors for developing EOGBS disease, feto–maternal and neonatal clinical data, their morbidities, mortalities, and length of hospital stay. Results: A total of 99 cases and 200 controls were included. The majority of cases presented in the first 72 hours of life (62/99 [63.9%], of which 87/99 (89.7% had at least one clinical risk factor for the development of EOGBS disease. Mothers of neonates with EOGBS disease were more likely to have GBS bacteriuria (odds ratio [OR] 10.76, 95% confidence interval [CI] 1.24–93.42, infection in the peripartum period (OR 8.92, CI 2.87–27.68, and temperature ≥38°C (OR 7.10, CI 2.50–20.17. GBS disease was associated with premature rupture of membranes and fetal tachycardia (P<0.01 for both. Neonates with EOGBS disease were more likely to have respiratory distress disease and convulsions, require tube feeding, and have longer hospital stays compared with the controls (P<0.01 for all. Stepwise multiple logistic

  18. Risk factors for basal cell carcinoma: a case-control study

    Directory of Open Access Journals (Sweden)

    Marcus Maia

    1995-02-01

    Full Text Available A controlled trial was performed with the purpose of investigating which factors could be considered of significant risk for the development of basal cell carcinoma. A total of 259 cases of basal cell carcinoma diagnosed from July 1991 to July 1992 were compared with 518 controls matched for age and sex. All subjects in both groups were white. Protocol data were submitted to statistical analysis by the chi-square test and by multiple conditional logistic regression analysis and the following conclusions were reached: 1 light skin color (types I and II of the Fitzpatrick classification, odds ratio of 2.8; outdoor work under constant sunlight, odds ratio of 5.0; the presence of actinic lesions due to exposure to the sun, odds ratio of 4.9, are risk factors perse. 2 Type III skin in the Fitzpatrick classification only represents a risk factor when the patient reports a history of intense sunburns, but not in the absence of such a history. 3 Sunburns per se do not represent a risk factor althorig the point made in item 2 of these conclusions is valid. 4 Other suspected risk factors whose significance was not confirmed by multiple conditioned logistic regression analysis were: residence in rural areas, light eyes and blond hair color, extent of the awareness of the "sun x skin cancer" relationship, familial occurrence of skin cancer, excessive exposure to the sun, and freckles appearing in childhood.

  19. The significance of microsatellite instability in colorectal cancer after controlling for clinicopathological factors.

    Science.gov (United States)

    Kang, Sanghee; Na, Younghyun; Joung, Sung Yup; Lee, Sun Il; Oh, Sang Cheul; Min, Byung Wook

    2018-03-01

    The colorectal cancer (CRC) patients with microsatellite instability (MSI) have distinct clinicopathological characteristics consisting of factors predicting positive and negative outcomes, such as a high lymph node harvest and poor differentiation. In this study, we measured the value of MSI as a prognostic factor after controlling for these discrepant factors. A total of 603 patients who underwent curative surgery for stages I to III colorectal cancer were enrolled. The patients were divided into microsatellite instability high (MSI-H) and microsatellite stable/microsatellite instability low (MSS/MSI-L) groups. Propensity score matching was used to match clinicopathological factors between the 2 groups. MSI-H patients had a high lymph node harvest (median: 31.0 vs 23.0, P controlling for pathological characteristics, MSI-H could be a potent prognostic factor regarding patient survival.

  20. Study of the Academic Members Attitude about Main Factors of Not Approaching to Scientific Writing in Hamadan University of Medical Sciences

    Directory of Open Access Journals (Sweden)

    M. Koorki

    2008-01-01

    Full Text Available Introduction & Objective: one of the important indicators of scientific study and science production in the universities is original research and its scientific article. The aim of this study was to determine the academic members’ attitude about main factors of not approaching to scientific writing in Hamadan Uni. Med. Sci.Material & Methods: The current survey was a descriptive cross-sectional study. Statistical population was all of the academic members of this university in 2006 (N=260. The data collected through a questionnaire consists of 2 parts: I. the demographic characteristics, II. the questions related to their attitude. After distribution of the questionnaires we received 228 completed ones. The data was statistically analyzed by SPSS software.Results: Outcomes showed that the main factors of not approaching to write the scientific articles were: education, teaching and treatment engagement mean with 3.891.16 of 5, the barriers of doing original research and writing the articles (3.880.93, long duration of sending and acceptation of articles in Persian scientific journals (3.841.07 and weakness of English language skill (3.831.05.Conclusion: The barriers of scientific writing were in 3 parts: organizational, personal and personal-organizational problems. The academic members’ activities and university managers’ supports are needed to remove these barriers.

  1. Evaluation of main control room habitability in Japanese LWR (1). Outline of evaluation method and conditions

    International Nuclear Information System (INIS)

    Fujita, Yuko; Yoneda, Jiro; Okabayashi, Kazuki; Fukuda, Ryo

    2009-01-01

    It has been recognized that main control room habitability (CRH) is very important safety item. Its evaluation method and conditions was recently updated as a common method both for Boiling Water Reactor (BWR) and Pressurized Water Reactor (PWR) in Japan. This paper describes the common procedure for CRH evaluation. Postulated accidents for CRH evaluation are Loss of Coolant Accident (LOCA) for BWR and PWR, Main Steam Line Break Accident(MSLBA) for BWR, and Steam Generator Tube Rupture(SGTR) for PWR. Evaluation period is thirty days after each accident occurs. Acceptable criterion for each operator is 100mSv as total effective dose equivalent for thirty days, considering the net staying period of an operator in a control room and frequency of alternation of working staff. Total effective dose equivalent is calculated not only for an operator in control room, but also for an operator outside a building for alternation, and then total effective dose is compared with the criterion. The routes for dose evaluation are classified into five patterns, covering three patterns of location of radioactive source (i.e. source inside a building, source released into air, and source leaked into a control room) and covering two patterns of location of an operator (i.e. in control room and outside a building for alternation). Total effective dose by a route for source which is released into air and leaked into a control room is typically the largest contributor, in case of PWR LOCA evaluation, as an example showing relatively severe result. Evaluated dose for this dominant route is significantly affected by two calculations. One is a source term for calculation of radioactive gas release and the other is dispersion calculation in the air for concentration of radioactive gas in the vicinity of a control room. For LOCA 100% Kr,Xe and 50% iodine of total core radionuclide inventory are assumed to be released immediately into containment vessel. This is the most conservative assumption

  2. Spatial and Temporal Epidemiology of Nephropathia Epidemica Incidence and Hantavirus Seroprevalence in Rodent Hosts: Identification of the Main Environmental Factors in Europe.

    Science.gov (United States)

    Monchatre-Leroy, E; Crespin, L; Boué, F; Marianneau, P; Calavas, D; Hénaux, V

    2017-08-01

    In Europe, the increasing number of nephropathia epidemica (NE) infections in humans, caused by Puumala virus carried by bank voles (Myodes glareolus), has triggered studies of environmental factors driving these infections. NE infections have been shown to occur in specific geographical areas characterized by environmental factors that influence the distribution and dynamics of host populations and virus persistence in the soil. Here, we review the influence of environmental conditions (including climate factors, food availability and habitat conditions) with respect to incidence in humans and seroprevalence in rodents, considering both direct and indirect transmission pathways. For each type of environmental factor, results and discrepancies between studies are presented and examined in the light of biological hypotheses. Overall, food availability and temperature appear to be the main drivers of host seroprevalence and NE incidence, but data quality and statistical approaches varied greatly among studies. We highlight the issues that now need to be addressed and suggest improvements for study design in regard to the current knowledge on hantavirus epidemiology. © 2016 Blackwell Verlag GmbH.

  3. Bureaucracy and Culture: Toward Two-Factor Theory of Organizational Control

    Directory of Open Access Journals (Sweden)

    Tomasz Olejniczak

    2014-03-01

    Full Text Available Purpose: In this article we focus on the issue of organizational control in its bureaucratic and cultural forms. Methodology: This research uses exploratory case study analysis of Matsushita Konosuke’s management style of in the early years of the Panasonic Corporation. Findings: First of all, we fi nd that despite the impressive body of knowledge accumulated over the years, some questions concerning the relationship between two modes of control and their changes over time still remain unanswered. As a result of case study analysis we put forward an original model illustrating the relationship between bureaucratic and cultural modes of control over stages of the organization life cycle. Research implications and limitations: Implications of the study consist of prescriptions on how to successfully exert control by combining formal and informal measures. Main limitations of the study are related to its generalizability. Originality: Originality of the study results both from putting forward a new theoretical models and using original historical case of Panasonic Corporation.

  4. Modeling and Control of DC/DC Boost Converter using K-Factor Control for MPPT of Solar PV System

    DEFF Research Database (Denmark)

    Vangari, Adithya; Haribabu, Divyanagalakshmi; Sakamuri, Jayachandra N.

    2015-01-01

    This paper is focused on the design of a controller for the DC/DC boost converter using K factor control, which is based on modified PI control method, for maximum power point tracking (MPPT) of solar PV system. A mathematical model for boost converter based on small signal averaging approach...... is presented. Design of the passive elements of the boost converter as per the system specifications is also illustrated. The performance of the proposed K factor control method is verified with the simulations for MPPT on solar PV system at different atmospheric conditions. A new circuit based model for solar...... PV array, which includes the effect of solar insolation and temperature on PV array output, for the application in power system transient simulations, is also presented. The performance of the PV array model is verified with simulations at different atmospheric conditions. A 160W PV module from BP...

  5. Safety factor profile control in a tokamak

    CERN Document Server

    Bribiesca Argomedo, Federico; Prieur, Christophe

    2014-01-01

    Control of the Safety Factor Profile in a Tokamak uses Lyapunov techniques to address a challenging problem for which even the simplest physically relevant models are represented by nonlinear, time-dependent, partial differential equations (PDEs). This is because of the  spatiotemporal dynamics of transport phenomena (magnetic flux, heat, densities, etc.) in the anisotropic plasma medium. Robustness considerations are ubiquitous in the analysis and control design since direct measurements on the magnetic flux are impossible (its estimation relies on virtual sensors) and large uncertainties remain in the coupling between the plasma particles and the radio-frequency waves (distributed inputs). The Brief begins with a presentation of the reference dynamical model and continues by developing a Lyapunov function for the discretized system (in a polytopic linear-parameter-varying formulation). The limitations of this finite-dimensional approach motivate new developments in the infinite-dimensional framework. The t...

  6. Risk factors in lateral epicondylitis (tennis elbow): a case-control study.

    Science.gov (United States)

    Titchener, A G; Fakis, A; Tambe, A A; Smith, C; Hubbard, R B; Clark, D I

    2013-02-01

    Lateral epicondylitis is a common condition, but relatively little is known about its aetiology and associated risk factors. We have undertaken a large case-control study using The Health Improvement Network database to assess and quantify the relative contributions of some constitutional and environmental risk factors for lateral epicondylitis in the community. Our dataset included 4998 patients with lateral epicondylitis who were individually matched with a single control by age, sex, and general practice. The median age at diagnosis was 49 (interquartile range 42-56) years . Multivariate analysis showed that the risk factors associated with lateral epicondylitis were rotator cuff pathology (OR 4.95), De Quervain's disease (OR 2.48), carpal tunnel syndrome (OR 1.50), oral corticosteroid therapy (OR 1.68), and previous smoking history (OR 1.20). Diabetes mellitus, current smoking, trigger finger, rheumatoid arthritis, alcohol intake, and obesity were not found to be associated with lateral epicondylitis.

  7. Factors Leading to the Loss of Natural Elite Control of HIV-1 Infection.

    Science.gov (United States)

    Pernas, María; Tarancón-Diez, Laura; Rodríguez-Gallego, Esther; Gómez, Josep; Prado, Julia G; Casado, Concepción; Dominguez-Molina, Beatriz; Olivares, Isabel; Coiras, Maite; León, Agathe; Rodriguez, Carmen; Benito, Jose Miguel; Rallón, Norma; Plana, Montserrat; Martinez-Madrid, Onofre; Dapena, Marta; Iribarren, Jose Antonio; Del Romero, Jorge; García, Felipe; Alcamí, José; Muñoz-Fernández, M Ángeles; Vidal, Francisco; Leal, Manuel; Lopez-Galindez, Cecilio; Ruiz-Mateos, Ezequiel

    2017-12-06

    HIV-1 elite controllers (EC) maintain undetectable viral load (VL) in the absence of antiretroviral treatment. However, these subjects have heterogeneous clinical outcomes including a proportion loosing HIV-1 control over time. In this work we compared, in a longitudinal design, transient EC, analyzed before and after the loss of virological control, versus persistent EC. The aim was to identify factors leading to the loss of natural virological control of HIV-1-infection with a longitudinal retrospective study design. Gag-specific T-cell response was assessed by in vitro intracellular poly-cytokine production quantified by flow cytometry. Viral diversity and sequence-dating were performed in proviral DNA by PCR amplification at limiting dilution in env and gag genes. The expression profile of 70 serum cytokines and chemokines was assessed by multiplex immunoassays. We identified transient EC as subjects with low Gag-specific T-cell polyfunctionality, high viral diversity and high proinflammatory cytokines levels before the loss of control. Gag-specific T-cell polyfunctionality was inversely associated with viral diversity in transient controllers before the loss of control (r=-0.8; p =0.02). RANTES was a potential biomarker of transient control. This study identified, virological and immunological factors including inflammatory biomarkers associated with two different phenotypes within EC. These results may allow a more accurate definition of EC, which could help in a better clinical management of these individuals and in the development of future curative approaches. IMPORTANCE There is a rare group of HIV-infected patients who have the extraordinary capacity to maintain undetectable viral load levels in the absence of antiretroviral treatment, the so called HIV-1 elite controllers (EC). However, there is a proportion within these subjects that eventually loses this capability. In this work we found differences in virological and immune factors including soluble

  8. Risk and protective factors for spasmodic dysphonia: a case-control investigation.

    Science.gov (United States)

    Tanner, Kristine; Roy, Nelson; Merrill, Ray M; Kimber, Kamille; Sauder, Cara; Houtz, Daniel R; Doman, Darrin; Smith, Marshall E

    2011-01-01

    Spasmodic dysphonia (SD) is a chronic, incurable, and often disabling voice disorder of unknown pathogenesis. The purpose of this study was to identify possible endogenous and exogenous risk and protective factors uniquely associated with SD. Prospective, exploratory, case-control investigation. One hundred fifty patients with SD and 150 medical controls (MCs) were interviewed regarding their personal and family histories, environmental exposures, illnesses, injuries, voice use patterns, and general health using a previously vetted and validated epidemiologic questionnaire. Odds ratios and multiple logistic regression analyses (α<0.15) identified several factors that significantly increased the likelihood of having SD. These factors included (1) a personal history of mumps, blepharospasm, tremor, intense occupational and avocational voice use, and a family history of voice disorders; (2) an immediate family history of meningitis, tremor, tics, cancer, and compulsive behaviors; and (3) an extended family history of tremor and cancer. SD is likely multifactorial in etiology, involving both genetic and environmental factors. Viral infections/exposures, along with intense voice use, may trigger the onset of SD in genetically predisposed individuals. Future studies should examine the interaction among genetic and environmental factors to determine the pathogenesis of SD. Copyright © 2011 The Voice Foundation. Published by Mosby, Inc. All rights reserved.

  9. RIMACS, Reactor Inspection Main Control System

    International Nuclear Information System (INIS)

    2008-01-01

    1 - Description of program or function: RIMACS prepares for automatic inspection files on each inspection item for the reactor. These automatic inspection files provide the data to move RIROB (Reactor Inspection Robot) with laser by interpreting the coordinates of LASPO (Laser Positioner) and the laser detecting device of RIROB in three dimensional space. In addition, when RIROB arrives at the inspecting location, the files provide all values of the manipulator's motions to acquire the ultrasonic data. RIMACS provides various modules in order to perform these complex functions, and the functions are programmed on graphic user interface for the convenience of the user. RIMACS provides various functions, such as insertion of reactor production data, selection of the reactor for inspection, the creation of automatic inspection file, the selection of the inspection item, inspection simulation, and automatic inspection procedures. It also provides all other functions, which are necessary for the inspection, such as operating program download and manual control of LASPO and RIROB, the inspection simulation and the inspection status display by means of the graphic screen, and SODAS (ultra-Sonic Data Acquisition System) drive verification. 2 - Methods: Moving path and operation procedures for inspection robot are generated automatically with Kinematics algorithm. 3 - Restrictions on the complexity of the problem: A graphics display with MS-Window capability is required

  10. A ChIP-Seq benchmark shows that sequence conservation mainly improves detection of strong transcription factor binding sites.

    Directory of Open Access Journals (Sweden)

    Tony Håndstad

    Full Text Available BACKGROUND: Transcription factors are important controllers of gene expression and mapping transcription factor binding sites (TFBS is key to inferring transcription factor regulatory networks. Several methods for predicting TFBS exist, but there are no standard genome-wide datasets on which to assess the performance of these prediction methods. Also, it is believed that information about sequence conservation across different genomes can generally improve accuracy of motif-based predictors, but it is not clear under what circumstances use of conservation is most beneficial. RESULTS: Here we use published ChIP-seq data and an improved peak detection method to create comprehensive benchmark datasets for prediction methods which use known descriptors or binding motifs to detect TFBS in genomic sequences. We use this benchmark to assess the performance of five different prediction methods and find that the methods that use information about sequence conservation generally perform better than simpler motif-scanning methods. The difference is greater on high-affinity peaks and when using short and information-poor motifs. However, if the motifs are specific and information-rich, we find that simple motif-scanning methods can perform better than conservation-based methods. CONCLUSIONS: Our benchmark provides a comprehensive test that can be used to rank the relative performance of transcription factor binding site prediction methods. Moreover, our results show that, contrary to previous reports, sequence conservation is better suited for predicting strong than weak transcription factor binding sites.

  11. ENGINEERING AND ECONOMIC FACTORS AFFECTING THE INSTALLATION OF CONTROL TECHNOLOGIES FOR MULTIPOLLUTANT STRATEGIES

    Science.gov (United States)

    The report evaluates the engineering and economic factors associated with installing air pollution control technologies to meet the requirements of strategies to control sulfur dioxide (SO2), oxides of nitrogen (NOX), and mercury under the Clear Skies Act multipollutant control s...

  12. Study of factors controlling exposure dose and image quality of C-arm in operation room according to detector size of it (Mainly L-Spine AP study)

    Energy Technology Data Exchange (ETDEWEB)

    Chui, Sung Hyun; Jo, Hwang Woo [Dept. of Radiology, Kyung Hee University Hospital at Gangdong, Seoul (Korea, Republic of); Chun, Woon Kwan; Song, Ha Jin [Dept. of Nuclear Engineering, Chosun University, Gwangju (Korea, Republic of); Dong, Kyung Rae [Dept. of Radiological Technology, Gwangju Health University, Gwangju (Korea, Republic of); Choi, Eun Jin [Dept. of Public Health and Medicine, Dongshin University, Naju (Korea, Republic of)

    2015-02-15

    Time of operation has been reduced and accuracy of operation has been improved since C-arm, which offer real-time image of patient, was introduced in operation room. However, because of the contamination of patient, C-arm could not be used more appropriately. Therefore, this study is to know factors of controlling exposure dose, image quality and the exposed dose of health professional in operation room. Height of Wilson frame (bed for operation) was fixed at 130 cm. Then, Model 76-2 Phantom, which was set by assembling manual of Fluke Company, was set on the bed. Head/Spine Fluoroscopy AEC mode was set for exposure condition. According to detector size of C-arm, the absorbed dose per min was measured in the 7 steps OFD (cm) from 10 cm to 40 cm (10, 15, 20, 25, 30, 35, 40 cm). In each step of OFD, the absorbed dose per min of same diameter of collimation was measured. Moreover, using Nero MAX Model 8000, exposure dose per min was measured according to 3 step of distance from detector (20 cm, 60 cm, 100 cm). Finally, resolution was measured by CDRH Disc Phantom and magnification of each OFD was measured by aluminum stick bar. According to detector size of C-arm, difference of absorbed dose shows that the dose of 20 cm OFD is 1.750 times higher than the dose of 40 cm OFD. It means that the C-arm, which has smaller size of detector, shows the bigger difference of absorbed dose per min (p<0.05). In the difference of absorbed dose in the same step of OFD (from 20 cm to 40 cm), the absorbed dose of 9 inch detect or C-arm was 1.370 times higher than 12 inch' s (p<0.05). When OFD was set to 20 cm OFD, the absorbed dose of non-collimation case was approximately 0.816 times lower than the absorbed dose of collimation cases (p<0.05). When the distance was 20 cm from detector, exposed does includes first-ray and scatter-ray. When the distance was 60 cm and 100 cm from detector, exposed does includes just scatter-ray. So, there was the 2.200 times difference of absorbed

  13. [Cardiovascular risk factor control in a population with longstanding diabetes attending endocrinology departments].

    Science.gov (United States)

    Comi-Diaz, Cristina; Miralles-García, José M; Cabrerizo, Lucio; Pérez, María; Masramon, Xavier; De Pablos-Velasco, Pedro

    2010-12-01

    To determine the degree of control of cardiovascular risk factors (CVRF) in a sample of patients with diabetes mellitus (DM) attending Endocrinology and Nutrition Departments in Spain. An epidemiological, cross-sectional, multicenter and observational study involving 41 Departments of Endocrinology and Nutrition in Spain. Each department selected patients with DM with over 10 years of evolution, which were treated in outpatient settings. Demographic, anthropometric, clinical and biochemical data, including medication, were collected for each participant. 1159 patients who met the inclusion criteria were recruited. 52% of the participants were patients with type 2 DM. The mean duration of DM was 19.6 years. A proportion of 37%, 44%, 27.6% and 25.5% had good control of their blood pressure (BP), low density cholesterol (LDLc), lipids and glucose, respectively, and only 4.3% did well in all factors evaluated. The percentage of poorly controlled BP was four times higher in type 2 than in type 1 DM. Obesity, low cultural level and aggregation of cardiovascular risk factors were associated with poorer control. The degree of control of CVRF in diabetic patients with long disease duration is insufficient. Copyright © 2010 SEEN. Published by Elsevier Espana. All rights reserved.

  14. Human factors in remote control engineering development activities

    International Nuclear Information System (INIS)

    Clarke, M.M.; Hamel, W.R.; Draper, J.V.

    1983-01-01

    Human factors engineering, which is an integral part of the advanced remote control development activities at the Oak Ridge National Laboratory, is described. First, work at the Remote Systems Development Facility (RSDF) has shown that operators can perform a wide variety of tasks, some of which were not specifically designed for remote systems, with a dextrous electronic force-reflecting servomanipulator and good television remote viewing capabilities. Second, the data collected during mock-up remote maintenance experiments at the RSDF have been analyzed to provide guidelines for the design of human interfaces with an integrated advanced remote maintenance system currently under development. Guidelines have been provided for task allocation between operators, remote viewing systems, and operator controls. 6 references, 5 figures, 2 tables

  15. Forecasting optimal duration of a beer main fermentation process using the Kalman filter

    OpenAIRE

    Niyonsaba T.; Pavlov V.A.

    2016-01-01

    One of the most important processes of beer production is the main process of fermentation. In this process, the wort transforms into beer. The quality of beer depends on the dynamics of wort parameters. The main fermentation process continues for 10 days and requires high costs. Therefore, the main purpose of this article is to forecast the optimal duration of the beer main fermentation process and provide its optimal control. The Kalman filter can provide optimal control of the main ferment...

  16. Control of erythropoiesis by erythropoietin and stem cell factor: a novel role for Bruton's tyrosine kinase

    NARCIS (Netherlands)

    von Lindern, Marieke; Schmidt, Uwe; Beug, Hartmut

    2004-01-01

    Erythropoietin (Epo) and stem cell factor (SCF) are essential factors in the control of survival, expansion and differentiation of erythroid progenitors. Upon activation, their receptors, the EpoR and c-Kit, initiate multiple signalling pathways that control many cellular processes. To control

  17. Discussion on verification criterion and method of human factors engineering for nuclear power plant controller

    International Nuclear Information System (INIS)

    Yang Hualong; Liu Yanzi; Jia Ming; Huang Weijun

    2014-01-01

    In order to prevent or reduce human error and ensure the safe operation of nuclear power plants, control device should be verified from the perspective of human factors engineering (HFE). The domestic and international human factors engineering guidelines about nuclear power plant controller were considered, the verification criterion and method of human factors engineering for nuclear power plant controller were discussed and the application examples were provided for reference in this paper. The results show that the appropriate verification criterion and method should be selected to ensure the objectivity and accuracy of the conclusion. (authors)

  18. A main factors affecting average number of teats in pigs

    Directory of Open Access Journals (Sweden)

    Emil Krupa

    2016-09-01

    Full Text Available The influence of factors (breed, year and season of farrowing, herd, parity order, sire of litter, total number of born piglets - TNB, number of piglets born alive - NBA, number of weaned piglets - NW, and linear and quadratic regression on the number of teats, found for all piglets in the litter till ten days after born, expressed as arithmetic mean for each litter as sum of all teats number of each piglet in appropriate litter divided by number of piglets in this litter at first litter (ANT1 and second and subsequent litters (ANT2+ were analysed. The coefficient of determination was 0.46 and 0.33 for ANT1 and ANT2+, respectively. The statistically high influence (P<0.001 on ANT1 and ANT2+ was determined for year and season of farrowing, herd, parity order (only for ANT2+ and sire of litter effects. Impact of breed was found only on ANT2+ (P<0.001. The rest of factors have negligible of no impact on traits. Based on the data available for analyses, obtained results will serve as a relevant set-up in developing the model for genetic evaluation for these traits.

  19. Z80 based voltage and temperature monitor for the Main Ring control crate: the CC48 card

    International Nuclear Information System (INIS)

    Seino, K.

    1982-06-01

    Several years ago, there seemed to be a need to monitor the power supply voltages and temperatures in the three bay racks of the Main Ring service buildings. A few years ago, another engineer seemed to have done a preliminary design using analog voltage comparators. In late 1979, it was proposed to use a microprocessor instead of analog voltage comparators. It was dramatic that all the people at a meeting were excited about the idea and unanimously approved the project. The author can remember some of the reasons why they were so enthusiastic about the idea at the time, i.e., (1) it was new to have microprocessor based cards on the Main Ring control system, (2) programmable alarm limits were preferred to resistor dividers or potentiometers with analog voltage comparators, (3) it was the first to try the communication between a host computer and distributed intelligent cards. The author started the design on the CC48 in January, 1980 and completed in April, 1980. We had the prototype card working in July, 1980 and tested the card on the system in September, 1980. Seven CC48s of the pilot production were installed in July, 1981. We mass-produced 35 more cards and finished installing them around the Main Ring in May, 1982. The author talks about the hardware, software and operation on the CC48 card, and he will make some remarks on his experience on the project

  20. Human factors in aviation: Terminal control area boundary conflicts

    Science.gov (United States)

    Monan, William P.

    1989-01-01

    Air-to-air conflicts in the vicinity of Terminal Control Area (TCA) boundaries were studied to obtain a better understanding of the causal dynamics of these events with particular focus on human factor issues. The study dataset consisted of 381 Instrument Flight Rules/Visual Flight Rules (IFR/VFR) traffic conflicts in airspace layers above TCA ceiling and below TCA floors; 213 reports of incursions in TCA terminal airspace by VFR aircraft, of which 123 resulted in conflicts; and an additional set of reports describing problems with Air Traffic Control (ATC) services in and around TCAs. Results and conclusions are detailed.

  1. Estratificación epidemiológica en el control de los factores de riesgo de la tuberculosis Epidemiological stratification to control the risk factors of tuberculosis

    Directory of Open Access Journals (Sweden)

    Elba Nieves Moreno Díaz

    2011-12-01

    Full Text Available Se realizó un estudio descriptivo longitudinal, con el objetivo de implementar la estratificación epidemiológica en el control de los factores de riesgo de la tuberculosis, provincia Pinar del Río, 2008-2010. El universo de estudio lo constituyó, los habitantes de la provincia en cada uno de los años estudiados. Se revisó el registro de dispensarización y las encuestas epidemiológicas; de ellos se obtuvieron los factores de riesgo: alcoholismo, hábito de fumar, diabetes mellitus, ancianos solos, desnutrición, inmunodeprimidos y casos viviendo con VIH/Sida. Para el procesamiento de la información se trabajó con Microsoft Excel y MapInfo Professional. Se utilizó la metodología estratificación epidemiológica de riesgo hasta nivel municipal; los estratos para los factores de riesgo como para la enfermedad, se clasificaron en: muy alto, alto, mediano y bajo riesgo. Para determinar la significación de cambios se utilizó la prueba Mc Nemar. Los resultados mostraron que en el 2009, el 50% de los municipios que en la estratificación del 2008 estaban en el estrato de muy alto y alto riesgo, el 85,7% cambiaran de estratos, lo que indica un mejor control de los factores de riesgo. El proceso de estratificación en el 2010, no logró cambios favorables en los municipios con mayor riesgo en el 2008, estando el 65% clasificado en estratos de muy alto y alto riesgo, pues el plan de acción previsto, no fue ejecutado con efectividad y seriedad por los jefes de programa, debido a inestabilidad y ausencia de los mismos en los municipios de mayor riesgo.A descriptive, longitudinal study aimed at implementing epidemiological stratification to control the risk factors of tuberculosis in Pinar del Rio province was carried out form 2008 to 2010. The target group was comprised of the inhabitants of the province for each of the years under study. Records and epidemiological survey were revised; taking into account the risk factors of alcoholism

  2. Efficacy and safety of nerve growth factor for the treatment of neurological diseases:a meta-analysis of 64 randomized controlled trials involving 6,297 patients

    Institute of Scientific and Technical Information of China (English)

    Meng Zhao; Xiao-yan Li; Chun-ying Xu; Li-ping Zou

    2015-01-01

    OBJECTIVE:China is the only country where nerve growth factor is approved for large-scale use as a clinical medicine. More than 10 years ago, in 2003, nerve growth factor injection was listed as a national drug. The goal of this article is to evaluate comprehensively the efifcacy and safety of nerve growth factor for the treatment of neurological diseases. DATA RETRIEVAL:A computer-based retrieval was performed from six databases, including the Cochrane Library, PubMed, EMBASE, Sino Med, CNKI, and the VIP database, searching from the clinical establishment of nerve growth factor for treatment until December 31, 2013. The key words for the searches were “nerve growth factor, randomized controlled trials” in Chinese and in English. DATA SELECTION:Inclusion criteria: any study published in English or Chinese referring to randomized controlled trials of nerve growth factor; patients with neurological diseases such as peripheral nerve injury, central nerve injury, cranial neuropathy, and nervous system infections;patients older than 7 years; similar research methods and outcomes assessing symptoms; and measurement of nerve conduction velocities. The meta-analysis was conducted using Review Manager 5.2.3 software. MAIN OUTCOME MEASURES:The total effective rate, the incidence of adverse effects, and the nerve conduction velocity were recorded for each study. RESULTS:Sixty-four studies involving 6,297 patients with neurological diseases were included. The total effective rate in the group treated with nerve growth factor was significantly higher than that in the control group (P < 0.0001,RR: 1.35, 95%CI: 1.30–1.40). The average nerve conduction velocity in the nerve growth factor group was signiifcantly higher than that in the control group (P < 0.00001,MD: 4.59 m/s, 95%CI: 4.12–5.06). The incidence of pain or sclero-ma at the injection site in the nerve growth factor group was also higher than that in the control group (P < 0.00001,RR: 6.30, 95%CI: 3.53–11

  3. Development of the staffing evaluation technique for mental tasks of the advanced main control room

    International Nuclear Information System (INIS)

    Hsieh Tsungling; Yang Chihwei; Lin Chiuhsiangjoe

    2011-01-01

    The key goals of staffing and qualifications review element are to ensure that the right numbers of people with the appropriate skills and abilities are available to support plant operations and events. If the staffing level is too few, excessive stress that caused human errors possibly will be placed on the operators. Accordingly, this study developed a staffing evaluation technique based on CPM-GOMS for the mental tasks such as operations in the advanced main control room. A within-subject experiment was designed to examine the validity of the staffing evaluation technique. The results indicated the performance of evaluated staffing level via the staffing evaluation technique was significantly higher than that of non-evaluated staffing level; thus, validity of the staffing evaluation technique can be accepted. Finally, the implications for managerial practice on the findings of this study were discussed. (author)

  4. Emissions control of volatile organic compounds in petroleum industry; Controle de emissoes de compostos organicos volateis na industria do petroleo

    Energy Technology Data Exchange (ETDEWEB)

    Gutierres, Ricardo; Moreira, Andrea Cristina de Castro Araujo [PETROBRAS, Rio de Janeiro, RJ (Brazil). Centro de Pesquisas (CENPES). P e D de Energia e Desenvolvimento Sustentavel (PDEDS)

    2004-07-01

    Volatile organic compounds are among the most common pollutants emitted by refining processes. The sources of these emissions should be controlled for preserving the ambient air quality. This article outlines the main factors to be considered for defining an effective emissions control strategy and compares the major characteristics of the available control technologies. (author)

  5. Meta-analysis of the risk factor for endophthalmitis in patients after cataract surgery

    Directory of Open Access Journals (Sweden)

    Fei Wen

    2016-07-01

    Full Text Available AIM: To explore the main risk factors related to the incidence of endophthalmitis in patients after cataract surgery in China and to provide evidence for prevention. METHODS: The results of 5 studies on the main risk factors of endophthalmitis in patients after cataract surgery were analyzed by Meta-analysis method. RESULTS: The pooled odds ratio values and 95% CI of age(≥70, diabetes, vitreous overflow, operative time(≥10min, common operating room and control of using time of topical anesthetic were 1.81(95% CI: 1.43-1.69,3.66(95% CI: 1.64-8.16,2.21(95% CI: 1.46-3.32,3.54(95% CI: 2.47-5.06,2.77(95% CI: 2.07-3.72,2.09(95% CI: 1.53-2.86. CONCLUSION: The main risk factors of endophthalmitis were the age(≥70, diabetes, vitreous overflow, operative time(≥10min, common operating room and control of using time of topical anesthetic.

  6. Risk Factors Profile of Shoulder Dystocia in Oman: A Case Control Study

    Science.gov (United States)

    Al-Khaduri, Maha M.; Abudraz, Rania Mohammed; Al-Farsi, Yahya M.

    2014-01-01

    Objective This study aimed to assess the risk factor profile of shoulder dystocia and associated neonatal complications in Oman, a developing Arab country. Methods A retrospective case-control study was conducted among 111 cases with dystocia and 111 controls, identified during 1994-2006 period in a tertiary care hospital in Oman. Controls were randomly selected among women who did not have dystocia, and were matched to cases on the day of delivery. Data related to potential risk factors, delivery, and obstetric complications were collected. Results Dystocia was significantly associated with older maternal age, higher parity, larger BMI, diabetes, and previous record of dystocia. In addition, dystocia was associated more with vacuum and forceps deliveries. Routine traction (51%) was the most used manoeuvre. Among dystocia cases, 13% were associated with fetal complications of which Erb’s Palsy was the most prevalent (79%). Conclusion Our finding of significant associations with risk factors lays out the ground to develop a predictability index for shoulder dystocia, which would help in making it preventable. Further p rospective studies are required to confirm the obtained results. PMID:25337307

  7. Risk Factors Profile of Shoulder Dystocia in Oman: A Case Control Study

    Directory of Open Access Journals (Sweden)

    Maha M. Al-Khaduri

    2014-09-01

    Full Text Available Objective: This study aimed to assess the risk factor profile of shoulder dystocia and associated neonatal complications in Oman, a developing Arab country. Methods: A retrospective case-control study was conducted among 111 cases with dystocia and 111 controls, identified during 1994-2006 period in a tertiary care hospital in Oman. Controls were randomly selected among women who did not have dystocia, and were matched to cases on the day of delivery. Data related to potential risk factors, delivery, and obstetric complications were collected. Results: Dystocia was significantly associated with older maternal age, higher parity, larger BMI, diabetes, and previous record of dystocia. In addition, dystocia was associated more with vacuum and forceps deliveries. Routine traction (51% was the most used manoeuvre. Among dystocia cases, 13% were associated with fetal complications of which Erb’s Palsy was the most prevalent (79%. Conclusion: Our finding of significant associations with risk factors lays out the ground to develop a predictability index for shoulder dystocia, which would help in making it preventable. Further prospective studies are required to confirm the obtained results.

  8. Hospital visitors as controls in case-control studies

    Directory of Open Access Journals (Sweden)

    Gulnar Azevedo S Mendonça

    2001-10-01

    Full Text Available OBJECTIVE: Selecting controls is one of the most difficult tasks in the design of case-control studies. Hospital controls may be inadequate and random controls drawn from the base population may be unavailable. The aim was to assess the use of hospital visitors as controls in a case-control study on the association of organochlorinated compounds and other risk factors for breast cancer conducted in the main hospital of the "Instituto Nacional de Câncer" -- INCA (National Cancer Institute in Rio de Janeiro (Brazil. METHODS: The study included 177 incident cases and 377 controls recruited among female visitors. Three different models of control group composition were compared: Model 1, with all selected visitors; Model 2, excluding women visiting relatives with breast cancer; and Model 3, excluding all women visiting relatives with any type of cancer. Odds ratios (OR and 95% confidence intervals were calculated to test the associations. RESULTS: Age-adjusted OR for breast cancer associated with risk factors other than family history of cancer, except smoking and breast size, were similar in the three models. Regarding family history of all cancers, except for breast cancer, there was a decreased risk in Models 1 and 2, while in Model 3 there was an increased risk, but not statistically significant. Family history of breast cancer was a risk factor in Models 2 and 3, but no association was found in Model 1. In multivariate analysis a significant risk of breast cancer was found when there was a family history of breast cancer in Models 2 and 3 but not in Model 1. CONCLUSIONS: These results indicate that while investigating risk factors unrelated to family history of cancer, the use of hospital visitors as controls may be a valid and feasible alternative.

  9. Main Factors of Job Satisfaction among Primary School Educators: Factor Analysis of the Greek Reality

    Science.gov (United States)

    Saiti, Anna

    2007-01-01

    Job satisfaction is an important issue, but remains a complex one as it is difficult to measure. A wide range of factors such as the working environment, its manner of organisation, demography and individual circumstances, etc., can substantially affect the level of job satisfaction attained by individuals. Job satisfaction and the teaching…

  10. Human factors design review guidelines for advanced nuclear control room technologies

    International Nuclear Information System (INIS)

    O'Hara, J.; Brown, W.; Granda, T.; Baker, C.

    1991-01-01

    Advanced control rooms (ACRs) for future nuclear power plants are being designed utilizing computer-based technologies. The US Nuclear Regulatory Commission reviews the human engineering aspects of such control rooms to ensure that they are designed to good human factors engineering principles and that operator performance and reliability are appropriately supported in order to protect public health and safety. This paper describes the rationale, general approach, and initial development of an NRC Advanced Control Room Design Review Guideline. 20 refs., 1 fig

  11. Human factors review of nuclear power plant control room design. Final report

    International Nuclear Information System (INIS)

    Seminara, J.L.; Gonzalez, W.R.; Parsons, S.O.

    1976-11-01

    The human factors aspects of five representative nuclear power plant control rooms were evaluated using such methods as a checklist guided observation system, structured interviews with operators and trainers, direct observations of operator behavior, task analyses and procedure evaluation, and historical error analyses. The human factors aspects of design practices are illustrated, and many improvements in current practices are suggested. The study recommends that a detailed set of applicable human factors standards be developed to stimulate a uniform and systematic concern for human factors in design considerations

  12. Remarks on Risk-Sensitive Control Problems

    International Nuclear Information System (INIS)

    Menaldi, Jose-Luis; Robin, Maurice

    2005-01-01

    The main purpose of this paper is to investigate the asymptotic behavior of the discounted risk-sensitive control problem for periodic diffusion processes when the discount factor α goes to zero. If u α (θ,x) denotes the optimal cost function, θ being the risk factor, then it is shown that lim { α to 0}α u α (θ,x)=ξ(θ) where ξ(θ) is the average on ]0,θ[ of the optimal cost of the (usual) infinite horizon risk-sensitive control problem

  13. The Control Room Upgrade in Oskarshamn 2 Modernization Project Lesson Learned from Ongoing Human Factor design

    International Nuclear Information System (INIS)

    Thomas, Gunnarsson; Magnus, Eliasson

    2011-01-01

    Due to recent changes in Swedish commercial nuclear safety system requirements, OKG decided to make the changes required by the new safety requirements, apply for a 30-year license extension, and to concurrently make changes for a major power uprate; this project is called the Plant Life Extension project (PLEX). It was decided, in addition to several plant modifications, to re build the old control room to a new modern screen-based control room located in the same space as the old one, and with the same number of operators. This paper explains the approach taken when modernizing the control room as a part of the Oskarshamn 2 Modernization project PLEX, the results, and the lessons learned from this ongoing work. The combination of changes results in a modernization project that is expected to increase output power by approximately 50 MWe through increased efficiency and to result in an increase in thermal power from 1800 MWt to 2300 MWt (28%) and electrical power from 620 MWe to 840 MWe due to the power uprate. The license to operate OKG2 expires in 2012 The PLEX project is one of the most ambitious nuclear power plant modernization projects ever implemented, world-wide. The application of human factors engineering (HFE) and control room and HSI design is a complex challenge. The original main control room from 1975 in Oskarshamn 2, was quite compact and provided a fairly good overview of the process. New requirements for enhanced safety and other design changes in the process systems and instrumentation led to a step-wise installation of new information and control equipment in the control room. Since the control room was quite limited in space, the control room grew larger, and the new equipment was installed farther away from the operator workplaces into an adjacent control room. This was even the case for the new safety systems. These systems were functioning well separately as such, but in some cases their interfaces were inconsistent, leading to increased

  14. A retrospective likelihood approach for efficient integration of multiple omics factors in case-control association studies.

    Science.gov (United States)

    Balliu, Brunilda; Tsonaka, Roula; Boehringer, Stefan; Houwing-Duistermaat, Jeanine

    2015-03-01

    Integrative omics, the joint analysis of outcome and multiple types of omics data, such as genomics, epigenomics, and transcriptomics data, constitute a promising approach for powerful and biologically relevant association studies. These studies often employ a case-control design, and often include nonomics covariates, such as age and gender, that may modify the underlying omics risk factors. An open question is how to best integrate multiple omics and nonomics information to maximize statistical power in case-control studies that ascertain individuals based on the phenotype. Recent work on integrative omics have used prospective approaches, modeling case-control status conditional on omics, and nonomics risk factors. Compared to univariate approaches, jointly analyzing multiple risk factors with a prospective approach increases power in nonascertained cohorts. However, these prospective approaches often lose power in case-control studies. In this article, we propose a novel statistical method for integrating multiple omics and nonomics factors in case-control association studies. Our method is based on a retrospective likelihood function that models the joint distribution of omics and nonomics factors conditional on case-control status. The new method provides accurate control of Type I error rate and has increased efficiency over prospective approaches in both simulated and real data. © 2015 Wiley Periodicals, Inc.

  15. 5th National Audit Project (NAP5) on accidental awareness during general anaesthesia: summary of main findings and risk factors.

    Science.gov (United States)

    Pandit, J J; Andrade, J; Bogod, D G; Hitchman, J M; Jonker, W R; Lucas, N; Mackay, J H; Nimmo, A F; O'Connor, K; O'Sullivan, E P; Paul, R G; Palmer, J H M G; Plaat, F; Radcliffe, J J; Sury, M R J; Torevell, H E; Wang, M; Hainsworth, J; Cook, T M

    2014-10-01

    We present the main findings of the 5th National Audit Project (NAP5) on accidental awareness during general anaesthesia (AAGA). Incidences were estimated using reports of accidental awareness as the numerator, and a parallel national anaesthetic activity survey to provide denominator data. The incidence of certain/probable and possible accidental awareness cases was ~1:19,600 anaesthetics (95% confidence interval 1:16,700-23,450). However, there was considerable variation across subtypes of techniques or subspecialities. The incidence with neuromuscular block (NMB) was ~1:8200 (1:7030-9700), and without, it was ~1:135,900 (1:78,600-299,000). The cases of AAGA reported to NAP5 were overwhelmingly cases of unintended awareness during NMB. The incidence of accidental awareness during Caesarean section was ~1:670 (1:380-1300). Two-thirds (82, 66%) of cases of accidental awareness experiences arose in the dynamic phases of anaesthesia, namely induction of and emergence from anaesthesia. During induction of anaesthesia, contributory factors included: use of thiopental, rapid sequence induction, obesity, difficult airway management, NMB, and interruptions of anaesthetic delivery during movement from anaesthetic room to theatre. During emergence from anaesthesia, residual paralysis was perceived by patients as accidental awareness, and commonly related to a failure to ensure full return of motor capacity. One-third (43, 33%) of accidental awareness events arose during the maintenance phase of anaesthesia, mostly due to problems at induction or towards the end of anaesthesia. Factors increasing the risk of accidental awareness included: female sex, age (younger adults, but not children), obesity, anaesthetist seniority (junior trainees), previous awareness, out-of-hours operating, emergencies, type of surgery (obstetric, cardiac, thoracic), and use of NMB. The following factors were not risk factors for accidental awareness: ASA physical status, race, and use or omission

  16. Transcription Factor Zbtb20 Controls Regional Specification of Mammalian Archicortex

    DEFF Research Database (Denmark)

    Rosenthal, Eva Helga

    2010-01-01

    Combinatorial expression of sets of transcription factors (TFs) along the mammalian cortex controls its subdivision into functional areas. Unlike neocortex, only few recent data suggest genetic mechanisms controlling the regionalization of the archicortex. TF Emx2 plays a crucial role in patterning...... later on becoming restricted exclusively to postmitotic neurons of hippocampus (Hi) proper, dentate gyrus (DG), and two transitory zones, subiculum (S) and retrosplenial cortex (Rsp). Analysis of Zbtb20-/- mice revealed altered cortical patterning at the border between neocortex and archicortex...

  17. Prevalence of the main infectious causes of abortion in dairy cattle in Algeria

    Directory of Open Access Journals (Sweden)

    Derdour Salima-Yamina

    2017-09-01

    Full Text Available Introduction: Abortion in cattle is a major source of economic losses for the agriculture sector. It can be due to infectious or non-infectious factors. Among infectious factors, parasites, bacteria, viruses, and fungi can be involved. The present work investigated the prevalence of the main infectious agents of abortion in Algerian cattle. Material and Methods: Altogether 278 non-aborting and 82 aborting cows were analysed. Results: The prevalence ranged from 0% for Tritrichomonas foetus to 15% for Neospora caninum. Additionally, a case-control study was performed to find the association between the presence of the pathogens and the occurrence of abortion in cows. The odds ratios were significant for Neospora caninum, bovine herpes virus 4, BVD virus, Brucella abortus, Salmonella Dublin, Leptospira interrogans serovar Hardjo, and Coxiella burnetii. Conclusions: The pathogens enumerated here could be major causes of abortion among Algerian cattle.

  18. The association between biochemical control and cardiovascular risk factors in acromegaly.

    Science.gov (United States)

    Carmichael, John D; Broder, Michael S; Cherepanov, Dasha; Chang, Eunice; Mamelak, Adam; Said, Qayyim; Neary, Maureen P; Bonert, Vivien

    2017-03-09

    The study aim was to estimate the proportion of acromegaly patients with various comorbidities and to determine if biochemical control was associated with reduced proportion of cardiovascular risk factors. Data were from a single-center acromegaly registry. Study patients were followed for ≥12 months after initial treatment. Study period was from first to last insulin-like growth factor-I and growth hormone tests. Of 121 patients, 55% were female. Mean age at diagnosis was 42.4 (SD: 15.0). Mean study period was 8.8 (SD: 7.2) years. Macroadenomas were observed in 93 of 106 patients (87.7%), and microadenomas in 13 (12.3%). Initial treatment was surgery in 104 patients (86%), pharmacotherapy in 16 (13.2%), and radiation therapy in 1 (0.8%). Of 120 patients, 79 (65.8%) achieved control during the study period. New onset comorbidities (reported 6 months after study start) were uncommon (acromegaly compared to their controlled counterparts in this single-center registry. About a third of the patients remained uncontrolled after a mean of >8 years of treatment, demonstrating the difficulty of achieving control in some patients.

  19. Training of professional interpreters in Cuba: Its main historic backgrounds

    Directory of Open Access Journals (Sweden)

    Diana Oliveros-Domínguez

    2017-06-01

    Full Text Available The formation of interpreters in Cuba has as its main goal to train a professional who is able to mediate among Spanish speakers and not-Spanish speakers in our historic situation. This research article aims to analyze the main backgrounds of interpretation teaching at Universidad de Oriente, taking into account its dynamics and the didactic treatment of the cognitive factors involved in the interpretation process. This enables to deepen into the main characteristics of the process, through a study of short-term memory training and the didactic devices used for its improvement; and establish three main stages in the evolution.

  20. Applying human factors to the design of control centre and workstation of a nuclear reactor

    Energy Technology Data Exchange (ETDEWEB)

    Santos, Isaac J.A. Luquetti dos; Carvalho, Paulo V.R.; Goncalves, Gabriel de L., E-mail: luquetti@ien.gov.br [Instituto de Engenharia Nuclear (IEN/CNEN-RJ), Rio de Janeiro, RJ (Brazil); Souza, Tamara D.M.F.; Falcao, Mariana A. [Universidade Federal do Rio de Janeiro (UFRJ), Rio de Janeiro, RJ (Brazil). Dept. de Desenho Industrial

    2013-07-01

    Human factors is a body of scientific factors about human characteristics, covering biomedical, psychological and psychosocial considerations, including principles and applications in the personnel selection areas, training, job performance aid tools and human performance evaluation. Control Centre is a combination of control rooms, control suites and local control stations which are functionally related and all on the same site. Digital control room includes an arrangement of systems, equipment such as computers and communication terminals and workstations at which control and monitoring functions are conducted by operators. Inadequate integration between control room and operators reduces safety, increases the operation complexity, complicates operator training and increases the likelihood of human errors occurrence. The objective of this paper is to present a specific approach for the conceptual and basic design of the control centre and workstation of a nuclear reactor used to produce radioisotope. The approach is based on human factors standards, guidelines and the participation of a multidisciplinary team in the conceptual and basic phases of the design. Using the information gathered from standards and from the multidisciplinary team, an initial sketch 3D of the control centre and workstation are being developed. (author)

  1. Applying human factors to the design of control centre and workstation of a nuclear reactor

    International Nuclear Information System (INIS)

    Santos, Isaac J.A. Luquetti dos; Carvalho, Paulo V.R.; Goncalves, Gabriel de L.; Souza, Tamara D.M.F.; Falcao, Mariana A.

    2013-01-01

    Human factors is a body of scientific factors about human characteristics, covering biomedical, psychological and psychosocial considerations, including principles and applications in the personnel selection areas, training, job performance aid tools and human performance evaluation. Control Centre is a combination of control rooms, control suites and local control stations which are functionally related and all on the same site. Digital control room includes an arrangement of systems, equipment such as computers and communication terminals and workstations at which control and monitoring functions are conducted by operators. Inadequate integration between control room and operators reduces safety, increases the operation complexity, complicates operator training and increases the likelihood of human errors occurrence. The objective of this paper is to present a specific approach for the conceptual and basic design of the control centre and workstation of a nuclear reactor used to produce radioisotope. The approach is based on human factors standards, guidelines and the participation of a multidisciplinary team in the conceptual and basic phases of the design. Using the information gathered from standards and from the multidisciplinary team, an initial sketch 3D of the control centre and workstation are being developed. (author)

  2. Integration of biomass into urban energy systems for heat and power. Part II: Sensitivity assessment of main techno-economic factors

    International Nuclear Information System (INIS)

    Pantaleo, Antonio M.; Giarola, Sara; Bauen, Ausilio; Shah, Nilay

    2014-01-01

    Highlights: • Application of a MILP tool for optimal sizing and location of heating and CHP plants to serve residential energy demand. • Trade-offs between local vs centralized heat generation, district heating vs natural gas distribution systems. • Assessment of the key factors influencing the use of biomass and district heating in residential areas. - Abstract: The paper presents the application of a mixed integer linear programming (MILP) methodology to optimize multi-biomass and natural gas supply chain strategic design for heat and power generation in urban areas. The focus is on spatial and temporal allocation of biomass supply, storage, processing, transport and energy conversion (heat and CHP) to match the heat demand of residential end users. The main aim lies on the assessment of the trade-offs between centralized district heating plants and local heat generation systems, and on the decoupling of the biomass processing and biofuel energy conversion steps. After a brief description of the methodology, which is presented in detail in Part I of the research, an application to a generic urban area is proposed. Moreover, the influence of energy demand typologies (urban areas energy density, heat consumption patterns, buildings energy efficiency levels, baseline energy costs and available infrastructures) and specific constraints of urban areas (transport logistics, air emission levels, space availability) on the selection of optimal bioenergy pathways for heat and power is assessed, by means of sensitivity analysis. On the basis of these results, broad considerations about the key factors influencing the use of bioenergy into urban energy systems are proposed. Potential further applications of this model are also described, together with main barriers for development of bioenergy routes for urban areas

  3. Controlling factors of uranium mineralization and prospect prediction in Qimantage area

    International Nuclear Information System (INIS)

    Yao Chunling; Zhu Pengfei; Cai Yuqi; Zhang Wenming; Zhao Yong'an; Song Jiye; Zhang Xiaojin

    2011-01-01

    Based on the analysis of regional geology in Qimantage area, the condition for uranium mineralization is summarized in regional geology setting, volcanic, granite and faults. This study shows that this area has favorable prospect for uranium mineralization. The metallogenic model is built up according to the controlling factors over uranium mineralization. Under this model, six potential areas are predicted in MRAS software with mineralization factors of synthetically geological information method. (authors)

  4. Factors influencing the quality of patient data captured by nurses for the tuberculosis control programme in Oshakati District, Namibia

    Directory of Open Access Journals (Sweden)

    Linda V. Kagasi

    2013-07-01

    Full Text Available Effective tuberculosis control relies heavily upon the general health system of the country, particularly on well-functioning primary healthcare services. This study investigated factors influencing the quality of data for the tuberculosis control programme in Oshakati district in Namibia. A quantitative, contextual, cross-sectional descriptive survey was conducted using 50 nursing personnel of different cadres who were sampled from five departments in Oshakati State Hospital. Data was collected by means of a self-administered questionnaire. Most participants reported that tuberculosis-related training improved correct recording and reporting amongst nursing personnel, which is a requirement for a quality tuberculosis control programme. The number of documents to be completed for each patient influences the quality of data recording and completeness. Factors such as the lack of resources and of adequate training as well as knowledge of tuberculosis control guidelines, in particular the use of records to capture the core tuberculosis indicators, influence the quality of data in the tuberculosis control programme. Knowledge, attitudes and practice are the main factors influencing the quality of data in the tuberculosis control programme in Oshakati district. Die effektiewe beheer van tuberkulose steun grootliks op die algemene gesondheidstelsel van ’n land, veral op die goeie werkende primêre gesondheidsorgdienste. Die studie het faktore wat die gehalte van data vir die teringbeheerprogram in die Oshakati Distrik in Namibië ondersoek.’n Kwantitatiewe, kontekstuele, kruisseksionele, beskrywende opname was onderneem met ’n steekproef van 50 verpleegpersoneel van verskillende kadres uit vyf departemente in Oshakati Staatshospitaal. Data was deur middel van ’n selftoegediende vraelys ingewin. Die meeste deelnemers het genoem dat teringverwante opleiding die korrekte afneem en rapportering onder verpleegpersoneel verbeter het, wat

  5. Risk Factors for Bile Duct Injury After Percutaneous Thermal Ablation of Malignant Liver Tumors: A Retrospective Case-Control Study.

    Science.gov (United States)

    Lin, Man-Xia; Ye, Jie-Yi; Tian, Wen-Shuo; Xu, Ming; Zhuang, Bo-Wen; Lu, Ming-De; Xie, Xiao-Yan; Kuang, Ming

    2017-04-01

    Bile duct injury after ablation of malignant liver tumors (MLTs) was not unusual and should be avoided. However, few studies have focused on evaluating the risk factors for intrahepatic bile duct injury. To evaluate the risk factors for intrahepatic bile duct injury after ablation of MLTs and to evaluate the minimum safe distance for ablating tumors abutting bile ducts. Sixty-five patients with intrahepatic bile duct injury after ablation of MLTs, and 65 controls were recruited. Risk factors for intrahepatic bile duct injury were analyzed. Tumor location was recorded as ≤5 mm (group A), 5-10 mm (group B), and >10 mm (group C) from the right/left main duct or segmental bile duct. Ascites history (P bile duct dilatation before ablation (P bile duct injury. Significant differences in the risk of intrahepatic bile duct injury were found between groups B and C (P = 0.000), but not between groups A and B (P = 0.751). Ascites history (P = 0.002) and tumor location (P Bile duct injury after ablation of MLTs was the result of local treatment-related factors combined with the patients' general condition. The minimum safe distance for ablation of tumor abutting a bile duct was 10 mm.

  6. Relation between diagnosis of atheromatous plaque from orthopantomographs and cardiovascular risk factors. A study of cases and control subjects

    Science.gov (United States)

    Gutierrez-Bonet, Carmen; Leco-Berrocal, Isabel; Fernández-Cáliz, Fernando; Martínez-González, José-María

    2016-01-01

    Background In recent years the use of orthopantomography has been proposed as a low-cost, reliable and non-invasive diagnostic medium for detecting atheromatous plaque. The purpose of this study was to correlate the presence of carotid calcifications (atheroma) in orthopantomographs with specific risk factors for cerebrovascular accidents (previous cerebrovascular accidents, arterial hypertension, and diabetes). Material and Methods The methods used in this observational study of cases and control subjects followed STROBE (Strengthening the Reporting of Observational studies in Epidemiology) recommendations. The study analyzed a total of 1,602 panoramic radiographs taken for dental diagnostic purposes between January 2010 and February 2014. The main variables analyzed were the incidence of atheromatous plaque and other cardiovascular risk factors. Epidat 3.1 statistical software was used to determine minimum sample sizes and the results were analyzed using PASW (Predictive Analytics Software) Statistics 10.0.0. Results For all the variables analyzed, the correlation between radiographic detection of atheromatous plaque and the presence of cardiovascular disease risk factors was found to be statistically significant (RR>1.5). Conclusions The presence of cardiovascular risk factors is related to the incidence of radiopaque lesions at the carotid artery bifurcation, indicating the presence of atheromatous plaque. Key words:Orthopantomography, atheromatous plaque, cerebrovascular accident, diabetes, arterial hypertension. PMID:26595828

  7. AN ASSESSMENT OF FACTORS AFFECTING MATERIAL STOCK CONTROL PRACTICE ON SELECTED CONSTRUCTION SITES IN NIGERIA

    OpenAIRE

    Adafin, Johnson Kayode; Ayodele, Elijah Olusegun; Daramola, Olufemi

    2011-01-01

    This research examines the stock control methods utilized by construction firms on construction sites with a view to assessing the factors affecting material stock control practice by construction firms as well as determining the impact of factors affecting material stock control on building project performance. Data were collected with the aid of well-structured questionnaire administered on a number of construction professionals and technicians in some randomly selected building constructio...

  8. Parental 'affectionless control' as an antecedent to adult depression: a risk factor refined.

    Science.gov (United States)

    Mackinnon, A; Henderson, A S; Andrews, G

    1993-02-01

    It has been well established that individuals with a history of depression report their parents as being less caring and more overprotective of them than do controls. 'Affectionless control' in childhood has thus been proposed as a risk factor for depression. Evidence is presented from a logistic regression analysis of data from a volunteer community sample that lack of care rather than over-protection is the primary risk factor. No evidence for an interaction effect of low care and over-protection was found.

  9. From nano- to macro-scale: nanotechnology approaches for spatially controlled delivery of bioactive factors for bone and cartilage engineering.

    Science.gov (United States)

    Santo, Vítor E; Gomes, Manuela E; Mano, João F; Reis, Rui L

    2012-07-01

    The field of biomaterials has advanced towards the molecular and nanoscale design of bioactive systems for tissue engineering, regenerative medicine and drug delivery. Spatial cues are displayed in the 3D extracellular matrix and can include signaling gradients, such as those observed during chemotaxis. Architectures range from the nanometer to the centimeter length scales as exemplified by extracellular matrix fibers, cells and macroscopic shapes. The main focus of this review is the application of a biomimetic approach by the combination of architectural cues, obtained through the application of micro- and nanofabrication techniques, with the ability to sequester and release growth factors and other bioactive agents in a spatiotemporal controlled manner for bone and cartilage engineering.

  10. Main factors for fatigue failure probability of pipes subjected to fluid thermal fluctuation

    International Nuclear Information System (INIS)

    Machida, Hideo; Suzuki, Masaaki; Kasahara, Naoto

    2015-01-01

    It is very important to grasp failure probability and failure mode appropriately to carry out risk reduction measures of nuclear power plants. To clarify the important factors for failure probability and failure mode of pipes subjected to fluid thermal fluctuation, failure probability analyses were performed by changing the values of a stress range, stress ratio, stress components and threshold of stress intensity factor range. The important factors for the failure probability are range, stress ratio (mean stress condition) and threshold of stress intensity factor range. The important factor for the failure mode is a circumferential angle range of fluid thermal fluctuation. When a large fluid thermal fluctuation acts on the entire circumferential surface of the pipe, the probability of pipe breakage increases, calling for measures to prevent such a failure and reduce the risk to the plant. When the circumferential angle subjected to fluid thermal fluctuation is small, the failure mode of piping is leakage and the corrective maintenance might be applicable from the viewpoint of risk to the plant. (author)

  11. Fuzzy comprehensive evaluation of multiple environmental factors for swine building assessment and control.

    Science.gov (United States)

    Xie, Qiuju; Ni, Ji-Qin; Su, Zhongbin

    2017-10-15

    In confined swine buildings, temperature, humidity, and air quality are all important for animal health and productivity. However, the current swine building environmental control is only based on temperature; and evaluation and control methods based on multiple environmental factors are needed. In this paper, fuzzy comprehensive evaluation (FCE) theory was adopted for multi-factor assessment of environmental quality in two commercial swine buildings using real measurement data. An assessment index system and membership functions were established; and predetermined weights were given using analytic hierarchy process (AHP) combined with knowledge of experts. The results show that multi-factors such as temperature, humidity, and concentrations of ammonia (NH 3 ), carbon dioxide (CO 2 ), and hydrogen sulfide (H 2 S) can be successfully integrated in FCE for swine building environment assessment. The FCE method has a high correlation coefficient of 0.737 compared with the method of single-factor evaluation (SFE). The FCE method can significantly increase the sensitivity and perform an effective and integrative assessment. It can be used as part of environmental controlling and warning systems for swine building environment management to improve swine production and welfare. Copyright © 2017 Elsevier B.V. All rights reserved.

  12. Fine scale spatial variability of microbial pesticide degradation in soil: scales, controlling factors, and implications

    Directory of Open Access Journals (Sweden)

    Arnaud eDechesne

    2014-12-01

    Full Text Available Pesticide biodegradation is a soil microbial function of critical importance for modern agriculture and its environmental impact. While it was once assumed that this activity was homogeneously distributed at the field scale, mounting evidence indicates that this is rarely the case. Here, we critically examine the literature on spatial variability of pesticide biodegradation in agricultural soil. We discuss the motivations, methods, and main findings of the primary literature. We found significant diversity in the approaches used to describe and quantify spatial heterogeneity, which complicates inter-studies comparisons. However, it is clear that the presence and activity of pesticide degraders is often highly spatially variable with coefficients of variation often exceeding 50% and frequently displays nonrandom spatial patterns. A few controlling factors have tentatively been identified across pesticide classes: they include some soil characteristics (pH and some agricultural management practices (pesticide application, tillage, while other potential controlling factors have more conflicting effects depending on the site or the pesticide. Evidence demonstrating the importance of spatial heterogeneity on the fate of pesticides in soil has been difficult to obtain but modelling and experimental systems that do not include soil’s full complexity reveal that this heterogeneity must be considered to improve prediction of pesticide biodegradation rates or of leaching risks. Overall, studying the spatial heterogeneity of pesticide biodegradation is a relatively new field at the interface of agronomy, microbial ecology, and geosciences and a wealth of novel data is being collected from these different disciplinary perspectives. We make suggestions on possible avenues to take full advantage of these investigations for a better understanding and prediction of the fate of pesticides in soil.

  13. Simulation of the control system for the KEK main ring power supply-II

    International Nuclear Information System (INIS)

    Kabe, Atsushi; Sato, Hikaru; Masuda, Masayoshi; Takeda, Masahiro; Nakano, Michio

    1977-05-01

    The tracking error between the magnetic field of the bending magnets and that of the quadrupole magnets is a very important problem of the KEK main ring power supply. Tacking performance is simulated using DDS (Digital Dynamics Simulator) in cases of 8 GeV and 12 GeV operation of the KEK main ring. The results of simulation coincide with the data of actual system. (auth.)

  14. Effectiveness of exercise intervention and health promotion on cardiovascular risk factors in middle-aged men: a protocol of a randomized controlled trial

    Science.gov (United States)

    2013-01-01

    Background Although cardiovascular disease has decreased, there is still potential for prevention as obesity and diabetes increase. Exercise has a positive effect on many cardiovascular risk factors, and it can significantly reduce the components of metabolic syndrome. The main challenge with exercise in primary care is how to succeed in motivating the patients at risk to change and increase their exercise habits. The objective of this study is to modify the cardiovascular risk in middle-aged men, either through a health promotion intervention alone or combined with an exercise intervention. Methods/design During a two-year period we recruit 300 men aged from 35 to 45 years with elevated cardiovascular risk (> two traditional risk factors). The men are randomized into three arms: 1) a health promotion intervention alone, 2) both health promotion and exercise intervention, or 3) control with usual community care and delayed health promotion (these men receive the intervention after one year). The main outcome measures will be the existence of metabolic syndrome and physical activity frequency (times per week). The participants are assessed at baseline, and at 3, 6, and 12 months. The follow-up of the study will last 12 months. Discussion This pragmatic trial in primary health care aimed to assess the effect of a health promotion programme with or without exercise intervention on cardiovascular risk and physical activity in middle-aged men. The results of this study may help to plan the primary care interventions to further reduce cardiovascular mortality. The study was registered at the Controlled Trials ( http://www.controlled-trials.com). Trial number: ISRCTN80672011. The study received ethics approval from the Coordinating Ethics Committee at Helsinki University Hospital on 8 June 2009 (ref: 4/13/03/00/09). PMID:23398957

  15. Q-factor control of multilayer micromembrane using PZT composite material

    Science.gov (United States)

    Čekas, Elingas; Janušas, Giedrius; Palevicius, Arvydas; Janušas, Tomas; Ciganas, Justas

    2018-02-01

    Cantilever and membrane based sensors, which are capable of providing accurate detection of target analytes have been always an important research topic of medical diagnostics, food testing, and environmental monitoring fields. Here, the mechanical detection is achieved by micro- and nano-scale cantilevers for stress sensing and mass sensing, or micro- and nano-scale plates or membranes. High sensitivity is a major issue for the active element and it could be achieved via increased Q-factor. The ability to control the Q factor expands the range of application of the device and allows to achieve more accurate results. The aim of this paper is to investigate the mechanical and electrical properties, as well as, the ability to control the Q factor of the membrane with PZT nanocomposite. This multilayered membrane was formatted using the n-type silicon substrate by implementing the Low Pressure Chemical Vapor Deposition (LPCVD), photolithography by using photomask with defined dimensions, deep etching, and e-beam evaporation techniques. Dynamic and electrical characteristics of the membrane were numerically investigated using COMSOL Multiphysics software. The use of the multilayered membrane can range from simple monitoring of particles concentration in a closed environment to inspecting glucose levels in human fluids (blood, tears, sweat, etc.).

  16. Determination of power peak factor using control rods, ex-core detectors and neural networks

    International Nuclear Information System (INIS)

    Souza, Rose Mary Gomes do Prado

    2005-01-01

    This work presents a methodology based on the artificial neural network technique to predict in real time the power peak factor in a form that can be implemented in reactor protection systems. The neural network inputs were those available in the reactor protection systems, namely, the axial and quadrant power differences obtained from measured ex-core detector signals, and the position of control rods. The response of ex core detector signals was measured in experiments especially performed in the IPEN/MB-01 zero-power reactor. Several reactor states with different power density distribution were obtained by positioning the control rods in different configurations. The power distribution and its peak factor were calculated for each of these reactor states using the Citation code. The obtained results show that the power peak factor correlates well with the control rod position and the quadrant power difference, and with a lesser degree with the axial power differences. The data presented an inherent organisation and could be classified into different classes of power peak factor behaviour as a function of position of control rods, axial power difference and quadrant power difference. The RBF networks were able to identify classes and interpolate the power peak factor values. The relative error for the power peak factor estimation ranged from 0.19 % to 0.67 %, less than the one that was obtained performing a power density distribution map with in-core detectors. It was observed that the positions of control rods bear the detailed and localised information about the power density distribution, and that the axial and the quadrant power difference describe its global variations in the axial and radial directions. The results showed that the RBF and MLP networks produced similar results, and that a neural network correlation can be implemented in power reactor protection systems. (author)

  17. A case-control study of risk factors for male infertility in Southern ...

    African Journals Online (AJOL)

    Aim: The purpose of this study was to evaluate the association between selected potential socio-demographic and behavioural risk factors and infertility in Nigeria males. Methods: The study consisted of cases and controls. The cases were 150 males with proven male infertility, while the controls were 150 fertile males with ...

  18. Associated factors with attention deficit hyperactivity disorder (ADHD): a case-control study.

    Science.gov (United States)

    Malek, Ayyoub; Amiri, Shahrokh; Sadegfard, Majid; Abdi, Salman; Amini, Saeedeh

    2012-09-01

    The current study attempted to investigate factors associated with attention deficit hyperactivity disorder (ADHD) in children without co-morbidities. In this case-control study, 164 ADHD children who attended the Child and Adolescent Psychiatric Clinics of Tabriz University of Medical Sciences, Iran were compared with 166 normal children selected in a random-cluster method from primary and secondary schools. Clinical interviews based on DSM-IV-TR using K-SADS were used to diagnose ADHD cases and to select the control group. Participants were matched for age. We used chi-square and binary logistic regression for data analysis. Among the associated factors with ADHD were gender and maternal employment. Boys (OR 0.54; 95% confidence interval: 0.34 - 0.86) and those children with working mothers (OR 0.16: 95% confidence interval: 0.06 - 0.86) suffered more from ADHD. The birth season, family size, birth order, and parental kinship were not among risk factors for ADHD. The results of the study show that maternal employment and male gender are among the associated risk factors for ADHD.

  19. A human factors experiment on the event-paced control tasks issue

    Energy Technology Data Exchange (ETDEWEB)

    Lee, Hyun Chul; Park, Jae Chang; Oh, In Seok; Lee, Jung Woon; Lee, Ki Young; Park, Jong Kyun [Korea Atomic Energy Research Institute, Taejeon (Korea)

    2000-03-01

    KEPRI(Korea Electric Power Research Institute) requires human factors validation tests according to the progress of the KNGR MMI design. This report describes the experimental results of an human factors validation issue, Event-Paced Control Tasks issue. The Event-Paced Control Task issue is to test that the designed MMI shall support operators in performing control tasks in pace with the plant dynamics. Task completion time and successful execution are defined as performance measures on the issue. Through an experiment on the issue with 3 scenarios and 5 subjects, we report that the variation of task completion time between subjects has a narrow band for each scenarios, however two among the total 15 experimental runs result in the failure that subject does not reach to the predefined operational goal. Incorrect operational strategy, insufficient training, and MMI design discrepancies are inferred as the causes of the failures. However these experimental results don't indicate the close of the Event-Paced Control Tasks issue. The validation test results under the experimental environment composed of the partial MMI representations, an unstable simulator, and insufficient subject training, are significant in the limited conditions. Thus, for the purpose of the complete issue close, the validation test on the Event-Paced Control Tasks issue should be repeatedly carried out in pace with the performance improvement of the experimental environment. 13 figs., 4 tabs. (Author)

  20. Lyapunov-based distributed control of the safety-factor profile in a tokamak plasma

    International Nuclear Information System (INIS)

    Bribiesca Argomedo, Federico; Witrant, Emmanuel; Prieur, Christophe; Brémond, Sylvain; Nouailletas, Rémy; Artaud, Jean-François

    2013-01-01

    A real-time model-based controller is developed for the tracking of the distributed safety-factor profile in a tokamak plasma. Using relevant physical models and simplifying assumptions, theoretical stability and robustness guarantees were obtained using a Lyapunov function. This approach considers the couplings between the poloidal flux diffusion equation, the time-varying temperature profiles and an independent total plasma current control. The actuator chosen for the safety-factor profile tracking is the lower hybrid current drive, although the results presented can be easily extended to any non-inductive current source. The performance and robustness of the proposed control law is evaluated with a physics-oriented simulation code on Tore Supra experimental test cases. (paper)

  1. Relationship of associated secondary hyperparathyroidism to serum fibroblast growth factor-23 in end stage renal disease: A case-control study

    Science.gov (United States)

    Sliem, Hamdy; Tawfik, Gamal; Moustafa, Fadia; Zaki, Heba

    2011-01-01

    Introduction: Secondary hyperparathyroidism (SHPT) is an insidious disease that develops early in the course of chronic kidney disease (CKD) and increases in severity as the glomerular filtration rate deteriorates. Recent studies have identified fibroblast growth factor-23 (FGF23) as a new protein with phosphaturic activity. It is mainly secreted by osteoblasts and is now considered the most important factor for regulation of phosphorus homeostasis. It is not yet proven if there is any direct relation between parathyroid hormone (PTH) and FGF23. The present study aims to evaluate the relation between serum FGF23, phosphorus, and PTH in end-stage renal disease in patients with SHPT on regular hemodialysis. Materials and Methods: Forty-six consecutive CKD adult patients (case group) and 20 healthy adults (control group) were included in the study. All patients had SHPT and were on regular hemodialysis. Both groups were subjected to full medical history, clinical examination and biochemical studies. Serum phosphorus, calcium, ferritin, hemoglobin level, blood urea, creatinine, PTH, and FGF23 were analyzed. Results: Levels of FGF23 were significantly higher in the case group in comparison with those in the control group, viz., 4-fold, and positively correlated with PTH. Phosphorus levels in the case group were significantly high in spite of the increasing levels of FGF23. Both PTH and FGF23 were positively correlated with phosphorus and negatively with hemoglobin levels. Conclusion: SHPT and FGF23 may have a partial role in the development of anemia in patients with CKD. FGF23 could be a central factor in the pathogenesis of SHPT. Its role in controlling hyperphosphatemia in CKD is vague. PMID:21731867

  2. Relationship of associated secondary hyperparathyroidism to serum fibroblast growth factor-23 in end stage renal disease: A case-control study

    Directory of Open Access Journals (Sweden)

    Hamdy Sliem

    2011-01-01

    Full Text Available Introduction: Secondary hyperparathyroidism (SHPT is an insidious disease that develops early in the course of chronic kidney disease (CKD and increases in severity as the glomerular filtration rate deteriorates. Recent studies have identified fibroblast growth factor-23 (FGF23 as a new protein with phosphaturic activity. It is mainly secreted by osteoblasts and is now considered the most important factor for regulation of phosphorus homeostasis. It is not yet proven if there is any direct relation between parathyroid hormone (PTH and FGF23. The present study aims to evaluate the relation between serum FGF23, phosphorus, and PTH in end-stage renal disease in patients with SHPT on regular hemodialysis. Materials and Methods: Forty-six consecutive CKD adult patients (case group and 20 healthy adults (control group were included in the study. All patients had SHPT and were on regular hemodialysis. Both groups were subjected to full medical history, clinical examination and biochemical studies. Serum phosphorus, calcium, ferritin, hemoglobin level, blood urea, creatinine, PTH, and FGF23 were analyzed. Results: Levels of FGF23 were significantly higher in the case group in comparison with those in the control group, viz., 4-fold, and positively correlated with PTH. Phosphorus levels in the case group were significantly high in spite of the increasing levels of FGF23. Both PTH and FGF23 were positively correlated with phosphorus and negatively with hemoglobin levels. Conclusion: SHPT and FGF23 may have a partial role in the development of anemia in patients with CKD. FGF23 could be a central factor in the pathogenesis of SHPT. Its role in controlling hyperphosphatemia in CKD is vague.

  3. New factors controlling the balance between osteoblastogenesis and adipogenesis.

    Science.gov (United States)

    Abdallah, Basem M; Kassem, Moustapha

    2012-02-01

    The majority of conditions associated with bone loss, including aging, are accompanied by increased marrow adiposity possibly due to shifting of the balance between osteoblast and adipocyte differentiation in bone marrow stromal (skeletal) stem cells (MSC). In order to study the relationship between osteoblastogenesis and adipogenesis in bone marrow, we have characterized cellular models of multipotent MSC as well as pre-osteoblastic and pre-adipocytic cell populations. Using these models, we identified two secreted factors in the bone marrow microenviroment: secreted frizzled-related protein 1 (sFRP-1) and delta-like1 (preadipocyte factor 1) (Dlk1/Pref-1). Both exert regulatory effects on osteoblastogenesis and adipogenesis. Our studies suggest a model for lineage fate determination of MSC that is regulated through secreted factors in the bone marrow microenvironment that mediate a cross-talk between lineage committed cell populations in addition to controlling differentiation choices of multipotent MSC. Copyright © 2011 Elsevier Inc. All rights reserved.

  4. [Estimation of the impact of risk factors control on non-communicable diseases mortality, life expectancy and the labor force lost in China in 2030].

    Science.gov (United States)

    Zeng, X Y; Li, Y C; Liu, J M; Liu, Y N; Liu, S W; Qi, J L; Zhou, M G

    2017-12-06

    Objective: To estimate the impact of risk factors control on non-communicable diseases (NCDs) mortality, life expectancy and the numbers of labor force lost in China in 2030. Methods: We used the results of China from Global Burden of Disease Study 2013, according to the correlation between death of NCDs and exposure of risk factors and the comparative risk assessment theory, to calculate population attributable fraction (PAF) and disaggregate deaths of NCDs into parts attributable and un-attributable. We used proportional change model to project risk factors exposure and un-attributable deaths of NCDs in 2030, then to get deaths of NCDs in 2030. Simulated scenarios according to the goals of global main NCDs risk factors control proposed by WHO were constructed to calculate the impact of risk factors control on NCDs death, life expectancy and the numbers of labor force lost. Results: If the risk factors exposure changed according to the trend of 1990 to 2013, compared to the numbers (8.499 million) and mortality rate (613.5/100 000) of NCDs in 2013, the death number (12.161 million) and mortality rate (859.2/100 000) would increase by 43.1% and 40.0% respectively in 2030, among which, ischemic stroke (increasing by 103.3% for death number and 98.8% for mortality rate) and ischemic heart disease (increasing by 85.0% for death number and 81.0% for mortality rate) would increase most quickly. If the risk factors get the goals in 2030, the NCDs deaths would reduce 2 631 thousands. If only one risk factor gets the goal, blood pressure (1 484 thousands NCDs deaths reduction), smoking (717 thousands reduction) and BMI (274 thousands reduction) would be the most important factors affecting NCDs death. Blood pressure control would have greater impact on ischemic heart disease (662 thousands reduction) and hemorrhagic stroke (449 thousands reduction). Smoking control would have the greatest effect on lung cancer (251 thousands reduction) and chronic obstructive pulmonary

  5. Human factors engineering control-room-design review/audit report: Palo Verde Nuclear Generating Station, Arizona Public Service Company

    International Nuclear Information System (INIS)

    Savage, J.W.; Lappa, D.A.

    1981-01-01

    A human factors engineering design review of the Palo Verde control room simulator was performed at the site on September 15 through September 17, 1981. Observed human factors design discrepancies were given priority ratings. This report summarizes the team's observations of the control room design and layout and of the control room operators' interface with the control room environment. A list of the human factors strengths observed in the Palo Verde control room simulator is given

  6. Perinatal mortality and associated risk factors: a case control study ...

    African Journals Online (AJOL)

    BACKGROUND: Perinatal mortality is reported to be five times higher in developing than in developed nations. Little is known about the commonly associated risk factors for perinatal mortality in Southern Nations National Regional State of Ethiopia. METHODS: A case control study for perinatal mortality was conducted in ...

  7. Physiology and Endocrinology Symposium. Factors controlling puberty in beef heifers

    Science.gov (United States)

    The Physiology and Endocrinology Symposium on “Factors controlling puberty in beef heifers” was held at the joint annual meeting of the American Dairy Science Association and the American Society of Animal Science in New Orleans, Louisiana, USA, July 10 to 14, 2011. The objective of the symposium w...

  8. A computerized main control room for NPP: Development and investigation

    International Nuclear Information System (INIS)

    Anokhin, A. N.; Marshall, E. C.; Rakitin, I. D.; Slonimsky, V. M.

    2006-01-01

    An ergonomics assessment of the control room at Leningrad Nuclear Power Plant has been undertaken as part of an international project funded by the EU TACIS program. The project was focused on the upgrading of the existing control facilities and the installation of a validation facility to evaluate candidate refurbishment proposals before their implementation at the plant. The ergonomics methodology applied in the investigation was wide ranging and included an analysis of reported events, extensive task analysis (including novel techniques) and validation studies using experienced operators. The paper addresses the potential difficulties for the human operator associated with fully computerized interfaces and shows how the validation facility and the outcomes from ergonomics assessment will be used to minimise any adverse impact on performance that may be caused by proposed control room changes. (authors)

  9. Quality control in the development of coagulation factor concentrates.

    Science.gov (United States)

    Snape, T J

    1987-01-01

    Limitation of process change is a major factor contributing to assurance of quality in pharmaceutical manufacturing. This is particularly true in the manufacture of coagulation factor concentrates, for which presumptive testing for poorly defined product characteristics is an integral feature of finished product quality control. The development of new or modified preparations requires that this comfortable position be abandoned, and that the effect on finished product characteristics of changes to individual process steps (and components) be assessed. The degree of confidence in the safety and efficacy of the new product will be determined by, amongst other things, the complexity of the process alteration and the extent to which the results of finished product tests can be considered predictive. The introduction of a heat-treatment step for inactivation of potential viral contaminants in coagulation factor concentrates presents a significant challenge in both respects, quite independent of any consideration of assessment of the effectiveness of the viral inactivation step. These interactions are illustrated by some of the problems encountered with terminal dry heat-treatment (72 h. at 80 degrees C) of factor VIII and prothrombin complex concentrates manufactured by the Blood Products Laboratory.

  10. Control of glycemia and other cardiovascular disease risk factors in older adults with type 2 diabetes mellitus: data from the Adult Diabetes Control and Management.

    Science.gov (United States)

    Sazlina, Shariff-Ghazali; Mastura, Ismail; Ahmad, Zaiton; Cheong, Ai-Theng; Adam, Bujang-Mohamad; Jamaiyah, Haniff; Lee, Ping-Yein; Syed-Alwi, Syed-Abdul-Rahman; Chew, Boon-How; Sriwahyu, Taher

    2014-01-01

    The aims of the present study were to assess the control of glycemia and other cardiovascular disease risk factors, and the association between age and these controls among older adults with type 2 diabetes in Malaysia. A cross-sectional study was carried out using cases notified to the Adult Diabetes Control and Management database between 1 January and 31 December 2009. A total of 10 363 people aged over 60 years with type 2 diabetes mellitus were included in the analyses. A standard online case report form was used to record demographic data, clinical factors (diabetes duration, comorbid condition and treatment modalities), cardiovascular disease risk factors, diabetes complications and laboratory assessments. The cardiovascular disease risk factors controls assessed included glycosylated hemoglobin (HbA(1c)) control of cardiovascular disease risk factors was suboptimal in older adults with type 2 diabetes. The oldest elderly were more likely to achieve target HbA(1c) (<7.0%) and triglycerides (<1.7 mmol/L) than older adults aged 60-69 years. © 2013 Japan Geriatrics Society.

  11. A possible methodological approach to setting up control level of radiation factors

    International Nuclear Information System (INIS)

    Devyatajkin, E.V.; Abramov, Yu.V.

    1986-01-01

    The mathematical formalization of the concept of control levels (CL) which enables one to obtain CL numerical values of controllable parameters required for rapid control purposes is described. The initial data for the assessment of environmental radioactivity are the controllable parameter values that is practical characteristic of controllable radiation factor showing technically measurable or calculation value. The controllable parameters can be divided into two classes depending on the degree of radiation effect on a man: possessing additivity properties (dosimetric class) and non-possessing (radiation class, which comprises the results of control of medium alteration dynamics, equipment operation safety, completeness of protection measures performance). The CL calculation formulas with account for requirements of radiation safety standards (RSS-76) are presented

  12. Main causes and factors associated with liver cirrhosis in patients in the General Hospital of Zone 2 of Chiapas, Mexico

    Directory of Open Access Journals (Sweden)

    Carlos Alfredo Meléndez González

    2012-08-01

    Full Text Available Background: Liver cirrhosis is a worldwide public health problem. Its main characteristic is low life expectancy. In Mexico, it is the second leading cause of death in the age group with the highest work productivity. Methods: The study is observational, retrospective, descriptive and cross-sectional. Data were collected on age, sex, occupation, origin, risk factors for liver damage and probable etiology of patients referred with a diagnosis of cirrhosis in a period of 2 years. Purpose: To determine the causes and factors associated with liver cirrhosis in our population. Results: Females prevailed over males by 57.2% over 42.7%. Average age was 55.27 and 55.02% were Tuxtla Gutierrez residents. The following risk factors were found: alcohol consumption (74.67%, diabetes mellitus (56.33%, obesity (41.92%, use of alternative medicines (19.22%, frequent use of drugs (12.66%, and transfusion (9.17%. Housewives were most affected (50.21% [95% CI 43.6-56.9]. Alcoholism in 47.59% was found to be a triggering factor; in 41.92% the cause was unexplained or cryptogenic; and in 5.24% the cause was chronic viral hepatitis. Portal hypertension data were found in 89.5%: 59.8% had esophageal varices, 37.11% had ascites, and 2.62% had chronic hepatic encephalopathy. VP > 11 mm in 18.7%. The prevalence during the study period was 9.85%. Conclusions: There are significant differences observed in gender and cause of cirrhosis in this study. In the future more research should be done to look into the conditions under which women live in the city of Tuxtla Gutierrez, as well as whether other idiosyncratic factors or cultural conditions are leading to a higher prevalence of cirrhosis in this population group in the Southeast of Mexico.

  13. Main factors of thermal fatigue failure induced by thermal striping and total simulation of thermal hydraulic and structural behaviors (research report)

    International Nuclear Information System (INIS)

    Kasahara, Naoto; Muramatsu, Toshiharu

    1999-01-01

    At incomplete mixing area of high temperature and low temperature fluids near the surface of structures, temperature fluctuation of fluid gives thermal fatigue damage to wall structures. This phenomenon is called thermal striping, which becomes sometimes a critical problem in LMFR plants. Since thermal striping phenomenon is characterized by the complex thermohydraulic and thermomechanical coupled problem, conventional evaluation procedures require mock-up experiments. In order to replace them by simulation-base methods, the authors have developed numerical simulation codes and applied them to analyze a tee junction of the PHENIX secondary circuit due to thermal striping phenomenon, in the framework of the IAEA coordinated research program (CRP). Through this analysis, thermohydraulic and thermomechanical mechanism of thermal striping phenomenon was clarified, and main factors on structural integrity was extracted in each stage of thermal striping phenomenon. Furthermore, simulation base evaluation methods were proposed taking above factors of structural integrity into account. Finally, R and D problems were investigated for future development of design evaluation methods. (author)

  14. Factors Controlling Nanoparticle Pharmacokinetics: An Integrated Analysis and Perspective

    DEFF Research Database (Denmark)

    Moghimi, Seyed Moien; Hunter, A.C.; Andresen, T.L.

    2012-01-01

    of interrelated core and interfacial physicochemical and biological factors. Pertinent to realizing therapeutic goals, definitive maps that establish the interdependency of nanoparticle size, shape, and surface characteristics in relation to interfacial forces, biodistribution, controlled drug release, excretion......Intravenously injected nanoparticulate drug carriers provide a wide range of unique opportunities for site-specific targeting of therapeutic agents to many areas within the vasculature and beyond. Pharmacokinetics and biodistribution of these carriers are controlled by a complex array...... are already on the market and many are in late-phase clinical trials. With concomitant advances in extensive computational knowledge of the genomics and epigenomics of interindividual variations in drug responses, the boundaries toward development of personalized nanomedicines can be pushed further....

  15. Microcapsule Technology for Controlled Growth Factor Release in Musculoskeletal Tissue Engineering.

    Science.gov (United States)

    Della Porta, Giovanna; Ciardulli, Maria C; Maffulli, Nicola

    2018-06-01

    Tissue engineering strategies have relied on engineered 3-dimensional (3D) scaffolds to provide architectural templates that can mimic the native cell environment. Among the several technologies proposed for the fabrication of 3D scaffold, that can be attractive for stem cell cultivation and differentiation, moulding or bioplotting of hydrogels allow the stratification of layers loaded with cells and with specific additives to obtain a predefined microstructural organization. Particularly with bioplotting technology, living cells, named bio-ink, and additives, such as biopolymer microdevices/nanodevices for the controlled delivery of growth factors or biosignals, can be organized spatially into a predesigned 3D pattern by automated fabrication with computer-aided digital files. The technologies for biopolymer microcarrier/nanocarrier fabrication can be strategic to provide a controlled spatiotemporal delivery of specific biosignals within a microenvironment that can better or faster address the stem cells loaded within it. In this review, some examples of growth factor-controlled delivery by biopolymer microdevices/nanodevices embedded within 3D hydrogel scaffolds will be described, to achieve a bioengineered 3D interactive microenvironment for stem cell differentiation. Conventional and recently proposed technologies for biopolymer microcapsule fabrication for controlled delivery over several days will also be illustrated and critically discussed.

  16. Transcription factor YY1 can control AID-mediated mutagenesis in mice.

    Science.gov (United States)

    Zaprazna, Kristina; Basu, Arindam; Tom, Nikola; Jha, Vibha; Hodawadekar, Suchita; Radova, Lenka; Malcikova, Jitka; Tichy, Boris; Pospisilova, Sarka; Atchison, Michael L

    2018-02-01

    Activation-induced cytidine deminase (AID) is crucial for controlling the immunoglobulin (Ig) diversification processes of somatic hypermutation (SHM) and class switch recombination (CSR). AID initiates these processes by deamination of cytosine, ultimately resulting in mutations or double strand DNA breaks needed for SHM and CSR. Levels of AID control mutation rates, and off-target non-Ig gene mutations can contribute to lymphomagenesis. Therefore, factors that control AID levels in the nucleus can regulate SHM and CSR, and may contribute to disease. We previously showed that transcription factor YY1 can regulate the level of AID in the nucleus and Ig CSR. Therefore, we hypothesized that conditional knock-out of YY1 would lead to reduction in AID localization at the Ig locus, and reduced AID-mediated mutations. Using mice that overexpress AID (IgκAID yy1 f/f ) or that express normal AID levels (yy1 f/f ), we found that conditional knock-out of YY1 results in reduced AID nuclear levels, reduced localization of AID to the Sμ switch region, and reduced AID-mediated mutations. We find that the mechanism of YY1 control of AID nuclear accumulation is likely due to YY1-AID physical interaction which blocks AID ubiquitination. © 2017 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  17. Risk factors for acute Toxoplasma gondii diseases in Taiwan: a population-based case-control study.

    Directory of Open Access Journals (Sweden)

    Ting-Yi Chiang

    Full Text Available Although human toxoplasmosis is a notifiable disease in Taiwan since 2007, little is known about its risk factors. This study aimed to investigate the risk factors for acute Toxoplasma gondii diseases in Taiwan. We conducted a nationwide population-based case-control study. Cases of acute human toxoplasmosis notified to the Taiwan Centers for Diseases Control (Taipei, Taiwan during 2008-2013 were compared with controls that were randomly selected from healthy T. gondii-seronegative blood donors who participated in a nationwide T. gondii seroepidemiologic study during 2009-2010. Cases and controls were matched according to age, gender and residency at an 1:8 ratio. Structured questionnaires were used to gather information regarding risk factors. A total of 30 laboratory-confirmed acute T. gondii disease cases and 224 controls were enrolled. The most common clinical manifestation of the cases was flu-like symptoms (n = 20, followed by central nervous system disease (n = 4, ocular diseases (n = 3, abortion (n = 2, and congenital infection (n = 1. Multivariate conditional logistic regression showed that raw clam consumption (adjusted odds ratio [OR] = 3.7; 95% confidence interval [CI] = 1.4-9.9 and having a cat in the household (adjusted OR = 2.9; 95% CI = 1.1-7.9 were two independent risk factors for acute T. gondii disease. We conclude that raw shellfish consumption and domestic cat exposure were risk factors for acquiring acute T. gondii diseases in Taiwan. This finding may guide future research and control policies.

  18. Control to goal of cardiometabolic risk factors among Nigerians living with type 2 diabetes mellitus.

    Science.gov (United States)

    Okafor, C I; Ofoegbu, E N

    2012-01-01

    Cardiovascular risk factors contribute to morbidity and mortality among diabetic patients. National and international guidelines on management of diabetes therefore emphasize control to goals of blood glucose, blood pressure, dyslipidemia, and obesity so as to minimize the development of complications and enhance the patients' quality of life. To evaluate the status of control to goals of cardiometabolic risk factors among the diabetic patients attending the Diabetes clinic of University of Nigeria Teaching Hospital, Enugu. A survey of 233 type 2 diabetic patients recruited from the Diabetes clinic of our hospital was carried out. Standard procedures as described in the WHO STEP instrument were used to determine the waist circumference, weight, height, and systolic and diastolic blood pressure. Fasting blood glucose and lipid profiles were also assessed. Therapeutic goals used to define risk or poor control were values adopted by expert groups such as American diabetes association (ADA), National cholesterol education program (NCEP), American association of clinical endocrinologist (AACE) and International diabetes federation (IDF). There were 98 males and 135 females with mean (SD) duration of diabetes mellitus (DM) of 6.7 (6.3) years. Suboptimal glycemic, blood pressure control and dyslipidemia were observed in 65.7%, 51.9%, 97.1% of the subjects respectively while 60.1% of the subjects were found to be overweight/obese. Comparing the mean indices of risk factors with the recommended therapeutic goals, status of control was optimal for HDL-cholesterol, waist circumference and triglycerides. All the other risk factors were suboptimal. Control to goals of cardiovascular risk factors is poor among the patients. There is the need to identify and tackle the possible contributing factors so as to reduce the morbidity and mortality in these patients.

  19. Association between job strain (high demand-low control and cardiovascular disease risk factors among petrochemical industry workers

    Directory of Open Access Journals (Sweden)

    Siamak Poorabdian

    2013-08-01

    Full Text Available Objective: One of the practical models for assessment of stressful working conditions due to job strain is "job demand and control" or Karasek's job strain model. This model explains how adverse physical and psychological effects including cardiovascular disease risk factors can be established due to high work demand. The aim was to investigate how certain cardiovascular risk factors including body mass index (BMI, heart rate, blood pressure, serum total cholesterol levels, and cigarette smoking are associated with job demand and control in workers. Materials and Methods: In this cohort study, 500 subjects completed "job demand and control" questionnaires. Factor analysis method was used in order to specify the most important "job demand and control" questions. Health check-up records of the workers were applied to extract data about cardiovascular disease risk factors. Ultimately, hypothesis testing, based on Eta, was used to assess the relationship between separated working groups and cardiovascular risk factors (hypertension and serum total cholesterol level. Results: A significant relationship was found between the job demand-control model and cardiovascular risk factors. In terms of chisquared test results, the highest value was assessed for heart rate (Chi2 = 145.078. The corresponding results for smoking and BMI were Chi2 = 85.652 and Chi2 = 30.941, respectively. Subsequently, Eta result for total cholesterol was 0.469, followed by hypertension equaling 0.684. Moreover, there was a significant difference between cardiovascular risk factors and job demand-control profiles among different working groups including the operational group, repairing group and servicing group. Conclusion: Job control and demand are significantly related to heart disease risk factors including hypertension, hyperlipidemia, and cigarette smoking.

  20. Human factors review of nuclear power plant control room design. Summary report

    International Nuclear Information System (INIS)

    Seminara, J.L.; Gonzalez, W.R.; Parsons, S.O.

    1976-11-01

    Human factors engineering is an interdisciplinary specialty concerned with influencing the design of equipment systems, facilities, and operational environments to promote safe, efficient, and reliable operator performance. The human factors aspects of five representative nuclear power plant control rooms were evaluated using such methods as a checklist-guided observation system, structured interviews with operators and trainers, direct observations of operator behavior, task analyses and procedure evaluation, and historical error analyses. The human factors aspects of design practices are illustrated, and many improvements in current practices are suggested. The study recommends that a detailed set of applicable human factors standards be developed to stimulate a uniform and systematic concern for human factors in design considerations

  1. Non-uniform temperature field measurement and simulation of a radio telescope’s main reflector under solar radiation

    International Nuclear Information System (INIS)

    Chen, Deshen; Qian, Hongliang; Wang, Huajie; Zhang, Gang; Fan, Feng; Shen, Shizhao

    2017-01-01

    Highlights: • Solar non-uniform temperature field test of a telescope’s reflector is conducted initially. • Time-varying distribution regularities are analyzed contrastively. • Simulation methods are proposed involving environmental factors and self-shadowing. • Refined discrimination method for the shadow distribution is put forward. • Validity of simulation methods is evaluated with the experimental data. - Abstract: To improve the ability of deep-space exploration, many astronomers around the world are actively engaged in the construction of large-aperture and high-precision radio telescopes. The temperature effect is one of three main factors affecting the reflector accuracy of radio telescopes. To study the daily non-uniform temperature field of the main reflector, experimental studies are first carried out with a 3-m-aperture radio telescope model. According to the test results for 16 working conditions, the distribution rule and time-varying regularity of the daily temperature field are summarized initially. Next, theoretical methods for the temperature field of the main reflector are studied considering multiple environmental parameters and self-shadows. Finally, the validity of the theoretical methods is evaluated with test results. The experimental study demonstrates that the non-uniform temperature distribution of the main reflector truly exists and should not be overlooked, and that the theoretical methods for the reflector temperature field proposed in this paper are effective. The research methods and conclusions can provide valuable references for thermal design, monitoring and control of similar high-precision radio telescopes.

  2. Perinatal serotonergic activity: A decisive factor in the control of food intake

    Directory of Open Access Journals (Sweden)

    Isabeli Lins PINHEIRO

    Full Text Available ABSTRACT The serotoninergic system controls key events related to proper nervous system development. The neurotransmitter serotonin and the serotonin transporter are critical for this control. Availability of these components is minutely regulated during the development period, and the environment may affect their action on the nervous system. Environmental factors such as undernutrition and selective serotonin reuptake inhibitors may increase the availability of serotonin in the synaptic cleft and change its anorectic action. The physiological responses promoted by serotonin on intake control decrease when requested by acute stimuli or stress, demonstrating that animals or individuals develop adaptations in response to the environmental insults they experience during the development period. Diseases, such as anxiety and obesity, appear to be associated with the body’s response to stress or stimulus, and require greater serotonergic system action. These findings demonstrate the importance of the level of serotonin in the perinatal period to the development of molecular and morphological aspects of food intake control, and its decisive role in understanding the possible environmental factors that cause diseases in adulthood.

  3. Safety review for human factors engineering and control rooms of nuclear power plants

    International Nuclear Information System (INIS)

    Yang Mengzhuo

    1998-01-01

    Safety review for human factors engineering and control rooms of nuclear power plants (NPP) is in a forward position of science and technology, which began at American TMI severe accident and had been implemented in China. The importance and the significance of the safety review are expounded, the requirements of its scope and profundity are explained in detail. In addition, the situation of the technical document system for nuclear safety regulation on human factors engineering and control rooms of NPP in China is introduced briefly, on which the safety review is based

  4. Organic Food Market in Poland – Main Characteristics and Factors of Development

    Directory of Open Access Journals (Sweden)

    Hermaniuk Tomasz

    2016-03-01

    Full Text Available Since the early nineties of the twentieth century in the international arena began the interest in the issues of sustainable consumption and production. Undoubtedly, an important category of products, which have a significant impact on the environment, are food products. The intensive agriculture focused mainly on performance and reduction of manufacturing costs leads inevitably to destructive actions that have measurable adverse effects on the environment.

  5. Interface design and human factors considerations for model-based tight glycemic control in critical care.

    Science.gov (United States)

    Ward, Logan; Steel, James; Le Compte, Aaron; Evans, Alicia; Tan, Chia-Siong; Penning, Sophie; Shaw, Geoffrey M; Desaive, Thomas; Chase, J Geoffrey

    2012-01-01

    Tight glycemic control (TGC) has shown benefits but has been difficult to implement. Model-based methods and computerized protocols offer the opportunity to improve TGC quality and compliance. This research presents an interface design to maximize compliance, minimize real and perceived clinical effort, and minimize error based on simple human factors and end user input. The graphical user interface (GUI) design is presented by construction based on a series of simple, short design criteria based on fundamental human factors engineering and includes the use of user feedback and focus groups comprising nursing staff at Christchurch Hospital. The overall design maximizes ease of use and minimizes (unnecessary) interaction and use. It is coupled to a protocol that allows nurse staff to select measurement intervals and thus self-manage workload. The overall GUI design is presented and requires only one data entry point per intervention cycle. The design and main interface are heavily focused on the nurse end users who are the predominant users, while additional detailed and longitudinal data, which are of interest to doctors guiding overall patient care, are available via tabs. This dichotomy of needs and interests based on the end user's immediate focus and goals shows how interfaces must adapt to offer different information to multiple types of users. The interface is designed to minimize real and perceived clinical effort, and ongoing pilot trials have reported high levels of acceptance. The overall design principles, approach, and testing methods are based on fundamental human factors principles designed to reduce user effort and error and are readily generalizable. © 2012 Diabetes Technology Society.

  6. Personality Factors Predicting Smartphone Addiction Predisposition: Behavioral Inhibition and Activation Systems, Impulsivity, and Self-Control.

    Science.gov (United States)

    Kim, Yejin; Jeong, Jo-Eun; Cho, Hyun; Jung, Dong-Jin; Kwak, Minjung; Rho, Mi Jung; Yu, Hwanjo; Kim, Dai-Jin; Choi, In Young

    2016-01-01

    The purpose of this study was to identify personality factor-associated predictors of smartphone addiction predisposition (SAP). Participants were 2,573 men and 2,281 women (n = 4,854) aged 20-49 years (Mean ± SD: 33.47 ± 7.52); participants completed the following questionnaires: the Korean Smartphone Addiction Proneness Scale (K-SAPS) for adults, the Behavioral Inhibition System/Behavioral Activation System questionnaire (BIS/BAS), the Dickman Dysfunctional Impulsivity Instrument (DDII), and the Brief Self-Control Scale (BSCS). In addition, participants reported their demographic information and smartphone usage pattern (weekday or weekend average usage hours and main use). We analyzed the data in three steps: (1) identifying predictors with logistic regression, (2) deriving causal relationships between SAP and its predictors using a Bayesian belief network (BN), and (3) computing optimal cut-off points for the identified predictors using the Youden index. Identified predictors of SAP were as follows: gender (female), weekend average usage hours, and scores on BAS-Drive, BAS-Reward Responsiveness, DDII, and BSCS. Female gender and scores on BAS-Drive and BSCS directly increased SAP. BAS-Reward Responsiveness and DDII indirectly increased SAP. We found that SAP was defined with maximal sensitivity as follows: weekend average usage hours > 4.45, BAS-Drive > 10.0, BAS-Reward Responsiveness > 13.8, DDII > 4.5, and BSCS > 37.4. This study raises the possibility that personality factors contribute to SAP. And, we calculated cut-off points for key predictors. These findings may assist clinicians screening for SAP using cut-off points, and further the understanding of SA risk factors.

  7. Personality Factors Predicting Smartphone Addiction Predisposition: Behavioral Inhibition and Activation Systems, Impulsivity, and Self-Control.

    Directory of Open Access Journals (Sweden)

    Yejin Kim

    Full Text Available The purpose of this study was to identify personality factor-associated predictors of smartphone addiction predisposition (SAP. Participants were 2,573 men and 2,281 women (n = 4,854 aged 20-49 years (Mean ± SD: 33.47 ± 7.52; participants completed the following questionnaires: the Korean Smartphone Addiction Proneness Scale (K-SAPS for adults, the Behavioral Inhibition System/Behavioral Activation System questionnaire (BIS/BAS, the Dickman Dysfunctional Impulsivity Instrument (DDII, and the Brief Self-Control Scale (BSCS. In addition, participants reported their demographic information and smartphone usage pattern (weekday or weekend average usage hours and main use. We analyzed the data in three steps: (1 identifying predictors with logistic regression, (2 deriving causal relationships between SAP and its predictors using a Bayesian belief network (BN, and (3 computing optimal cut-off points for the identified predictors using the Youden index. Identified predictors of SAP were as follows: gender (female, weekend average usage hours, and scores on BAS-Drive, BAS-Reward Responsiveness, DDII, and BSCS. Female gender and scores on BAS-Drive and BSCS directly increased SAP. BAS-Reward Responsiveness and DDII indirectly increased SAP. We found that SAP was defined with maximal sensitivity as follows: weekend average usage hours > 4.45, BAS-Drive > 10.0, BAS-Reward Responsiveness > 13.8, DDII > 4.5, and BSCS > 37.4. This study raises the possibility that personality factors contribute to SAP. And, we calculated cut-off points for key predictors. These findings may assist clinicians screening for SAP using cut-off points, and further the understanding of SA risk factors.

  8. Cooperative research for human factors review of advanced control rooms

    Energy Technology Data Exchange (ETDEWEB)

    Lee, Jung Woon; Park, Jae Chang; Lee, Yong Hee; Oh, In Seok; Lee, Hyun Chul

    2000-12-01

    This project has been performed as cooperative research between KAERI and USNRC. Human factors issues related to soft controls, which is one of key features of advanced HSI, are identified in this project. The issues are analyzed for the evaluation approaches in either experimental or analytical ways. Also, issues requiring additional researches for the evaluation of advanced HSI are identified in the areas of advanced information systems design, computer-based procedure systems, soft controls, human systems interface and plant modernization process, and maintainability of digital systems. The issues are analyzed to discriminate the urgency of researches on it to high, medium, and low levels in consideration of advanced HSI development status in Korea, and some of the issues that can be handled by experimental researches are identified. Additionally, an experimental study is performed to compare operator's performance on human error detection in advanced control rooms vs. in conventional control rooms. It is found that advanced control rooms have several design characteristics hindering operator's error detection performance compared to conventional control rooms.

  9. Cooperative research for human factors review of advanced control rooms

    International Nuclear Information System (INIS)

    Lee, Jung Woon; Park, Jae Chang; Lee, Yong Hee; Oh, In Seok; Lee, Hyun Chul

    2000-12-01

    This project has been performed as cooperative research between KAERI and USNRC. Human factors issues related to soft controls, which is one of key features of advanced HSI, are identified in this project. The issues are analyzed for the evaluation approaches in either experimental or analytical ways. Also, issues requiring additional researches for the evaluation of advanced HSI are identified in the areas of advanced information systems design, computer-based procedure systems, soft controls, human systems interface and plant modernization process, and maintainability of digital systems. The issues are analyzed to discriminate the urgency of researches on it to high, medium, and low levels in consideration of advanced HSI development status in Korea, and some of the issues that can be handled by experimental researches are identified. Additionally, an experimental study is performed to compare operator's performance on human error detection in advanced control rooms vs. in conventional control rooms. It is found that advanced control rooms have several design characteristics hindering operator's error detection performance compared to conventional control rooms

  10. Smoking as the main factor of preventable mortality in Serbia

    Directory of Open Access Journals (Sweden)

    Marinković Ivan

    2017-01-01

    Full Text Available The use of tobacco in Serbia has for many years been one of the most frequent risk factors affecting disease development. Although its impact is often neglected and the effects on health minimised, reviewing the existing literature and calculating the tobacco consumption impact on the mortality of the population in Serbia (using the Peto-Lopez method show a clear link between smoking and health of the population. Serbian population is heavily burdened with the negative effects of tobacco on health, especially men. At the beginning of the second decade of the 21st century, mortality from the illness or cause of death associated with smoking was at about 17% of the total mortality. In men, it is estimated that even a quarter of the total mortality is associated with smoking. In the female population, the share of smokers is considerably lower, and consequently the mortality from this factor is lower, about 9% of the total mortality. Of all major disease groups, tumours are most affected by smoking. The share of tobaccorelated mortality in neoplasms is high and accounts for 30% (43% in men and 14% in women. In cardiovascular diseases, the impact of smoking is much smaller and about 6,000 deaths per year are associated with the use of tobacco. Since the early 1990s, the number of smoking-attributable death has been growing. Relatively, the share of men has not changed, but for 20 years of analysis the share of women has significantly increased from 5% to 9%. In all age groups, the share of smoking-related mortality has increased in the female population, especially in the 45-69 age range where mortality has been doubled. Surveys on the health of the Serbian population also confirm the trend of increasing the share of women smokers in the population, especially in the categories of young people. Men in Serbia (35-69 years of age have the highest smoking-attributable death rate in Europe. As much as 44% of total deaths in that age are directly related

  11. Women's perceived internal control of future pregnancy outcomes and its related factors.

    Science.gov (United States)

    Maleki, Azam; Mazloomzadeh, Saeideh

    2013-03-01

    With regards to the importance of women's beliefs in improving pregnancy outcomes, this study was performed to determine the perceived internal control on future pregnancy outcomes and its related factors in women who participated in pre-marital counseling. In a cross-sectional study, women's perceived internal control was investigated. The study population comprised the women in reproductive age of whom 400 were selected by random sampling. Data collection instrument was a questionnaire consisting of demographic, pre-conceptional care, and internal control questions. Two categories of favorite and not favorite levels of internal control were defined based on the total score. The validity of the questionnaire was determined via content validity method by use of experts' opinion and its reliability was evaluated through the calculation of Cronbach's alpha coefficient which was 0.76. Data were analyzed through frequency tables, correlation coefficient, and Chi-square test at the confidence level of 0.95. Two hundred sixty-five (65%) women had a good perceived internal control and it was significantly associated with the age, educational level, and hearing about pre-conceptional care. The internal control score also showed a positive and significant correlation with both age and the subject knowledge about folic acid (r = 0.19 and r = 0.15, respectively). The majority of women had a favorite perceived internal control. Since age and educational level were the affecting factors on the perceived internal control of women, promoting the level of internal control in young women and those with low education in pre-marital counseling classes seems necessary.

  12. Heterogeneity of critical systems as the main factor determining their radiostability

    International Nuclear Information System (INIS)

    Gudkov, I.N.

    1984-01-01

    It is shown that meristem can be considered as a convenient object for investigating regularities in the propagation kinetics of cells of critical systems and mechanisms of its regulation. Critical organs are rather perfect heterogeneous systems of automatic control where processes of their propagation and functional activity occur under strict control of spectral regulation systems to provide permanent composition and amount of cells. These systems influence purposeful cell alterations when they pass separate stages of the cell cycle. They provide the formation of funds of reserve cells and reliability of functioning of these highely sensitive organism tissues

  13. Skin problems in ostomy patients: a case-control study of risk factors

    DEFF Research Database (Denmark)

    Nybaek, Hanne; Bang Knudsen, Dorte; Nørgaard Laursen, Troels

    2009-01-01

    Skin complications are frequent in ostomy patients and a number of risk factors have been suggested. The data on risk factors have, however, been documented mainly in single-centre studies and the actual importance of the suggested risk factors should therefore be verified in a group of ostomy...... patients broadly selected from the gene-ral population. All patients with permanent ostomies living in Roskilde County, Denmark, were invited to participate in the study. A total of 338 responded and 199 agreed to participate. Forty-five percent of all patients presented a skin problem. Less than half (43......%) of patients with a skin problem were aware of the skin problems, and less than 1 in 5 (16%) had sought treatment for their skin problem. Ileostomies, ostomies with leakage and ostomies in patients with body mass index >30 were associated with skin problems. In conclusion, ileostomy, leakage and obesity...

  14. Basal progesterone level as the main determinant of progesterone elevation on the day of hCG triggering in controlled ovarian stimulation cycles.

    Science.gov (United States)

    Papaleo, Enrico; Corti, Laura; Vanni, Valeria Stella; Pagliardini, Luca; Ottolina, Jessica; De Michele, Francesca; La Marca, Antonio; Viganò, Paola; Candiani, Massimo

    2014-07-01

    Modest increases of serum progesterone at human chorionic gonadotrophin (hCG) administration in controlled ovarian hyperstimulation (COH) cycles have been shown to have a negative impact on pregnancy outcomes. The aim of this study was to identify early predictors of progesterone elevation at hCG. Pregnancy outcome of 303 consecutive patients undergoing COH and fresh day-3 embryo transfer was analysed. Considering the non-linear relationship between progesterone at hCG triggering and pregnancy outcomes, partial area under the curve (pAUC) analysis was used to implement marker identification potential of receiver operating characteristic (ROC) curve analysis. Multivariate logistic analysis was then performed to identify predictors of progesterone rise. Pregnancy outcomes could be predicted by pAUC analysis (pAUC = 0.58, 95 % CI 0.51-0.66, p = 0.02) and a significant detrimental cut-off could be calculated (progesterone at hCG > 1.35 ng/ml). Total dose of rFSH administered, E2 level at hCG but mostly basal progesterone level (OR = 12.21, 95 % CI 1.82-81.70) were predictors of progesterone rise above the cut-off. Basal progesterone is shown to be the main prognostic factor for progesterone elevation. This observation should be taken into consideration in the clinical management of IVF/ICSI cycles to improve pregnancy outcomes.

  15. Case-controlled Study on Risk Factors for the Development of Constipation in Hospitalized Patients

    OpenAIRE

    Ueki, Tetsuya; Nagai, Keiko; Ooe, Nobuharu; Nakashima, Mihoko N.; Nishida, Koyo; Nakamura, Junzo; Nakashima, Mikiro

    2011-01-01

    Constipation is a common problem in hospitalized patients; however, the relative risks of its development with various factors have not been clarified. To clarify the risk factors associated with constipation, we performed a case-controlled study of 165 hospitalized patients who were not laxative users on admission. They were divided into case (n=35) and control (n=130) groups according to laxative administration during hospitalization. Comparison of the patient backgrounds in the two groups ...

  16. Extracellular matrix and growth factor engineering for controlled angiogenesis in regenerative medicine

    Directory of Open Access Journals (Sweden)

    Mikaël M Martino

    2015-04-01

    Full Text Available Blood vessel growth plays a key role in regenerative medicine, both to restore blood supply to ischemic tissues and to ensure rapid vascularization of clinical-size tissue-engineered grafts. For example, vascular endothelial growth factor (VEGF is the master regulator of physiological blood vessel growth and is one of the main molecular targets of therapeutic angiogenesis approaches. However, angiogenesis is a complex process and there is a need to develop rational therapeutic strategies based on a firm understanding of basic vascular biology principles, as evidenced by the disappointing results of initial clinical trials of angiogenic factor delivery. In particular, the spatial localization of angiogenic signals in the extracellular matrix is crucial to ensure the proper assembly and maturation of new vascular structures. Here we discuss the therapeutic implications of matrix interactions of angiogenic factors, with a special emphasis on VEGF, as well as provide an overview of current approaches, based on protein and biomaterial engineering that mimic the regulatory functions of extracellular matrix to optimize the signaling microenvironment of vascular growth factors.

  17. Causal Analysis of The Uncontrolled Moderator In The HFEF Main Cell

    Energy Technology Data Exchange (ETDEWEB)

    Posegate, Charles R. [Idaho National Lab. (INL), Idaho Falls, ID (United States); Crofts, Bryan P. [Idaho National Lab. (INL), Idaho Falls, ID (United States)

    2012-12-01

    On 11/07/2012 while investigating the cause of defects in neutron radiography film at HFEF, oil was discovered near the elevator shaft located at the 4M location within the Main Cell. Subsequent investigation identified oil (untracked moderator) in several locations ofthe HFEF Main Cell. Initial analysis determined that oil leaking from a 1M shielding window had leaked past a compensatory containment system resulting in a thin layer of oil found in several locations on the main cell floor. The result of this condition is uncontrolled moderator in moderator controlled zones, which is a violation of Criticality Hazard Control Statements (CHCS) for HFEF.

  18. The role of nutrition as risk factor for polyneuropathy : a case-control study

    NARCIS (Netherlands)

    Visser, Nora A.; Notermans, Nicolette C.; de Vries, Jeanne H.M.; van den Berg, Leonard H.; Vrancken, Alexander F.J.E.

    2017-01-01

    The aim of this case–control study is to investigate the role of nutrition as risk factor for polyneuropathy. Three hundred eighteen patients with chronic idiopathic axonal polyneuropathy and 636 matched controls completed a validated food frequency questionnaire that covered nutrient intake and

  19. 75 FR 5536 - Pipeline Safety: Control Room Management/Human Factors, Correction

    Science.gov (United States)

    2010-02-03

    ... DEPARTMENT OF TRANSPORTATION Pipeline and Hazardous Materials Safety Administration 49 CFR Parts...: Control Room Management/Human Factors, Correction AGENCY: Pipeline and Hazardous Materials Safety... following correcting amendments: PART 192--TRANSPORTATION OF NATURAL AND OTHER GAS BY PIPELINE: MINIMUM...

  20. Factors Associated with the Adoption of Food Safety Controls by the Mexican Meat Industry

    Science.gov (United States)

    Maldonado-Simán, Ema; Martínez-Hernández, Pedro Arturo; García-Muñiz, José G.; Cadena-Meneses, José

    Food marketing at international and domestic markets has focused on processing systems that improve food safety. The objective of this research is to determine the factors influencing the implementation of the HACCP system in the Mexican meat industry, and to identify the main marketing destination of their products. Only 18.5% of enterprises reports fully operational HACCP in their plants. The main destination of their production in the domestic market is supermarkets, suppliers and distributors and specific niches of the domestic market. Exports are to USA, Japan, Korea and Central America and some niches of the domestic market with requirements of higher quality. The four principal factors that motivate enterprises to adopt HACCP are associated with improvement of plant efficiency and profitability, adoption of good practices, improvement of product quality and waste reduction. It is concluded that Mexican enterprises adopt HACCP to successfully remain and face competition by foreign enterprises in the domestic market and to a lesser extent to compete in the international market.