RNA-seq analysis of Quercus pubescens Leaves: de novo transcriptome assembly, annotation and functional markers development.

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Sara Torre

Full Text Available Quercus pubescens Willd., a species distributed from Spain to southwest Asia, ranks high for drought tolerance among European oaks. Q. pubescens performs a role of outstanding significance in most Mediterranean forest ecosystems, but few mechanistic studies have been conducted to explore its response to environmental constrains, due to the lack of genomic resources. In our study, we performed a deep transcriptomic sequencing in Q. pubescens leaves, including de novo assembly, functional annotation and the identification of new molecular markers. Our results are a pre-requisite for undertaking molecular functional studies, and may give support in population and association genetic studies. 254,265,700 clean reads were generated by the Illumina HiSeq 2000 platform, with an average length of 98 bp. De novo assembly, using CLC Genomics, produced 96,006 contigs, having a mean length of 618 bp. Sequence similarity analyses against seven public databases (Uniprot, NR, RefSeq and KOGs at NCBI, Pfam, InterPro and KEGG resulted in 83,065 transcripts annotated with gene descriptions, conserved protein domains, or gene ontology terms. These annotations and local BLAST allowed identify genes specifically associated with mechanisms of drought avoidance. Finally, 14,202 microsatellite markers and 18,425 single nucleotide polymorphisms (SNPs were, in silico, discovered in assembled and annotated sequences. We completed a successful global analysis of the Q. pubescens leaf transcriptome using RNA-seq. The assembled and annotated sequences together with newly discovered molecular markers provide genomic information for functional genomic studies in Q. pubescens, with special emphasis to response mechanisms to severe constrain of the Mediterranean climate. Our tools enable comparative genomics studies on other Quercus species taking advantage of large intra-specific ecophysiological differences.

Retranslocation and localization of nutrient elements in various organs of moso bamboo (Phyllostachys pubescens)

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Umemura, Mitsutoshi, E-mail: mitsutoshi.ume@gmail.com; Takenaka, Chisato, E-mail: chisato@agr.nagoya-u.ac.jp

2014-09-15

Moso bamboo (Phyllostachys pubescens) is one of the major giant bamboo species growing in Japan, and the invasion of mismanaged bamboo populations into contiguous forests has been a serious problem. To understand expansion mechanisms of the bamboo, it is important to obtain some first insights into the plant's rapid growth from the viewpoints of the nutrient dynamics in bamboo organs. We have investigated seasonal changes in the concentrations of several nutrient elements in leaves of the plants from three P. pubescens forests and the distributions of those elements in both mature (culms, branches, leaves, roots, and rhizomes) and growing organs (shoots and rhizomes). Among all elements analyzed, boron (B) concentrations in leaves showed a specific seasonal variation that was synchronous across all study sites. Boron was detected at high concentrations in the younger parts of growing rhizomes and shoots, and in mature leaves. These results indicate that P. pubescens could actively utilize B for vegetative reproduction by the retranslocation and the local accumulation behaving as mobile B. Silicon (Si) was found in high concentrations in surface parts of culms and in the mature sheaths of growing rhizomes and shoots following those in mature leaves. P. pubescens, a plant known to accumulate Si, accumulated only low levels of Ca and B in the leaves, indicating that it is possible to utilize more Si for cell wall enhancement than Ca or B. In both mature culms and rhizomes, zinc (Zn) was found at much higher concentrations in the nodes with meristematic tissue than those in internodes, indicating that Zn might play a role in promoting culm and rhizome elongation. We suggest that specific and local utilization of B, Si, and Zn in P. pubescens might support the vegetative reproduction and rapid growth. - Highlights: • The bamboo efficiently utilizes boron by the retranslocation and local accumulation. • Zinc found in nodes at high concentrations may support

Retranslocation and localization of nutrient elements in various organs of moso bamboo (Phyllostachys pubescens)

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Umemura, Mitsutoshi; Takenaka, Chisato

2014-01-01

Moso bamboo (Phyllostachys pubescens) is one of the major giant bamboo species growing in Japan, and the invasion of mismanaged bamboo populations into contiguous forests has been a serious problem. To understand expansion mechanisms of the bamboo, it is important to obtain some first insights into the plant's rapid growth from the viewpoints of the nutrient dynamics in bamboo organs. We have investigated seasonal changes in the concentrations of several nutrient elements in leaves of the plants from three P. pubescens forests and the distributions of those elements in both mature (culms, branches, leaves, roots, and rhizomes) and growing organs (shoots and rhizomes). Among all elements analyzed, boron (B) concentrations in leaves showed a specific seasonal variation that was synchronous across all study sites. Boron was detected at high concentrations in the younger parts of growing rhizomes and shoots, and in mature leaves. These results indicate that P. pubescens could actively utilize B for vegetative reproduction by the retranslocation and the local accumulation behaving as mobile B. Silicon (Si) was found in high concentrations in surface parts of culms and in the mature sheaths of growing rhizomes and shoots following those in mature leaves. P. pubescens, a plant known to accumulate Si, accumulated only low levels of Ca and B in the leaves, indicating that it is possible to utilize more Si for cell wall enhancement than Ca or B. In both mature culms and rhizomes, zinc (Zn) was found at much higher concentrations in the nodes with meristematic tissue than those in internodes, indicating that Zn might play a role in promoting culm and rhizome elongation. We suggest that specific and local utilization of B, Si, and Zn in P. pubescens might support the vegetative reproduction and rapid growth. - Highlights: • The bamboo efficiently utilizes boron by the retranslocation and local accumulation. • Zinc found in nodes at high concentrations may support

Male Fruit Fly, Bactrocera tau (Diptera; Tephritidae) attractants from Elsholtzia pubescens Bth

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Hasyim, A.; Muryati,; Mizu Istianto,; Kogel, de W.J.

2007-01-01

Studies on the ability of different plant extracts to attract male fruit flies indicated that an extract of Elsholtzia pubescens attracted male Bactrocera tau fruit flies in Passion fruit orchards in West Sumatra, Indonesia. Analyses of the plant extract showed that the major compound present was

Regeneração de espécies nativas lenhosas sob plantio de Eucalyptus em área de Cerrado na Floresta Nacional de Paraopeba, MG, Brasil Regeneration of wood natives species under Eucalyptus stand of Cerrado area in the Floresta Nacional of Paraopeba, Minas Gerais, Brazil

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Andreza Viana Neri

2005-06-01

Full Text Available A regeneração de sub-bosques em plantios homogêneos tem estreita dependência de florestas vizinhas. Outros fatores exercem influência, como a ecologia da dispersão da espécie, os efeitos de borda e clareiras. Diante disto, procurou-se conhecer a florística e a estrutura da vegetação lenhosa de espécies nativas sob plantio de Eucalyptus em área de Cerrado na Floresta Nacional de Paraopeba, MG, e verificar a variação da riqueza, da densidade e de indivíduos zoocóricos e anemocóricos da borda para o interior do talhão. Para tal, foram alocadas cinco parcelas de 5×40 m, subdivididas em parcelas 5×10 m. Foram encontradas 47 espécies e destas as que se destacaram foram Magonia pubescens A. St.-Hil.e Miconia albicans (Sw. Triana, principalmente quanto à alta densidade. Das espécies amostradas 53% possuem dispersão zoocórica e 43% anemocórica. Verificou-se também a diminuição da riqueza, da densidade e da percentagem de indivíduos anemocóricos da borda para interior. Porém a percentagem de indivíduos zoocóricos aumentou no interior do talhão. A maior riqueza e densidade na borda dá-se pela dificuldade da dispersão de diásporos no interior do fragmento. O índice de diversidade (H'= 2,49 encontrado para este estudo foi próximo aos valores observados em estudos em regeneração sob Eucalyptus em áreas de Cerrado.The regeneration of understory in homogeneous stands is closely dependent of neighbour forests. Others factures also have influency such as the species dispersion ecology, the border effects and clearings. Therefore, the objective of this work were to study the floristic and structure of native woody plant species growing under stands of Eucalyptus in the Cerrado area in the Flona (Floresta Nacional - National Forest of Paraopeba, Minas Gerais, Brazil, and to determine the variations in richness, density and the zoochorous and anemochorous individual dispersions from the borders into the stand. To carry out

From the Western Alps across Central Europe: Postglacial recolonisation of the tufa stream specialist Rhyacophila pubescens (Insecta, Trichoptera

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Haase Peter

2011-05-01

Full Text Available Abstract Background Dispersal rates, i.e. the effective number of dispersing individuals per unit time, are the product of dispersal capacity, i.e. a species physiological potential for dispersal, dispersal behaviour, i.e. the decision to leave a habitat patch in favour of another, and connectivity of occupied habitat. Thus, dispersal of species that are highly specialised to a certain habitat is limited by habitat availability. Species inhabiting very stable environments may also adopt a sedentary life-style. Both factors should lead to strong genetic differentiation in highly specialised species inhabiting stable environments. These two factors apply to our model species Rhyacophila pubescens a highly specialised freshwater insect that occurs in tufa springs, a very stable habitat. Results We examined the genetic population structure and phylogeography using range-wide mtCOI sequence and AFLP data from 333 individuals of R. pubescens. We inferred the location of Pleistocene refugia and postglacial colonisation routes of R. pubescens, and examined ongoing local differentiation. Our results indicate intraregional differentiation with a high number of locally endemic haplotypes, that we attributed to habitat specificity and low dispersal rates of R. pubescens. We observed high levels of genetic diversity south of the Alps and genetic impoverishment north of the Alps. Estimates of migrants placed the refugium and the source of the colonisation in the Dauphiné Alps (SW Alps. Conclusions This is the first example of an aquatic insect with a colonisation route along the western margin of the Alps to the Central European highlands. The study also shows that specialisation to a stable environment may have promoted a behavioural shift to decreased dispersal rates, leading to stronger local population differentiation than in less specialised aquatic insects. Alternatively, the occurrence of highly specialised tufa spring habitats may have been more

[Chemical constituents from stems of Ilex pubescens].

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Xing, Xian-dong; Zhang, Qian; Feng, Feng; Liu, Wen-yuan

2012-09-01

To study the chemical constituents from the stems of Ilex pubescens Hook. et Am. The chemical constituents were isolated and purified by various column chromatographic methods with diatomite, silica gel, ODS and Sephadex LH-20. Their structures were identified on physical properties and spectroscopic methods. Nine compounds were isolated and determined as luteolin(1), quercetin(2), hyperoside(3), rutin(4), 1, 5-dihydroxy-3-methyl-anthraquinone(5),3,5-dimethoxy-4-hydroxy-benzoic acid-1-O-beta-D-glucoside(6), hexadecanoic acid(7), stearic acid(8), n-tetratriacontanol(9), respectively. All the compounds are isolated from this plant for the first time, and compounds 5 and 6 are isolated from this genus for the first time.

Traffic-emitted metal status and uptake by Carex meyeriana Kunth and Thelypteris palustris var. pubescens Fernald growing in roadside turfy swamp in the Changbai Mountain area, China.

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Wang, Hong; Nie, Lei; Xu, Yan; Li, Miao; Lv, Yan

2018-04-26

Six traffic-emitted metals (Cr, Zn, Cu, Cd, Pb, and Ni) were determined in soil and plants for below- and aboveground parts along different distances from highway to evaluate their behavior and uptake by Carex meyeriana Kunth and Thelypteris palustris var. pubescens Fernald growing in turfy swamps. The results indicated that the different plant tissues showed significantly different levels of metal content. Nonlinear regression analysis indicated that metal contents leveled off at constant values before they decreased as the distance from the roadside increased. The high R 2 values of the regression model indicated good fit of the exponential function applied to depict the distribution pattern of the metal elements. It was deduced that Cr, Cu, and Cd in Thelypteris palustris var. pubescens Fernald were mainly derived from the soil; Carex meyeriana Kunth and Thelypteris palustris var. pubescens Fernald absorbed Pb mainly through the stomata from atmospheric depositions; Cr, Cu, and Cd in Carex meyeriana Kunth and Zn in Thelypteris palustris var. pubescens Fernald were mainly affected by soil and atmospheric depositions. After excluding the effects of traffic, only the bioaccumulation factor of Cd (1.34) in Carex meyeriana Kunth and the translocation factor of Zn (1.13) in Thelypteris palustris var. pubescens Fernald were greater than 1, suggesting that Carex meyeriana Kunth could be a good candidate for assimilating Cd from soils and Thelypteris palustris var. pubescens Fernald could be suitable for the phytoextraction of Zn.

Rhizosphere bacterial diversity and heavy metal accumulation in Nymphaea pubescens in aid of phytoremediation potential

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RAISA KABEER

2014-04-01

Full Text Available The present work aims to characterize the bacterial diversity of the rhizosphere system of Nymphaea pubescens and the sediment system where it grows naturally. Heavy metal content in the sediment and Nymphea plant from the selected wetland system were also studied. Results of the current study showed that the concentration of copper, zinc and lead in the sediment ranged from 43 to 182 mg/Kg, from 331 to 1382 mg/Kg and from 121 to 1253 mg/Kg, respectively. Cadmium concentration in sediment samples was found to be zero and the order of abundance of heavy metals in the sediment samples was Zn>Pb>Cu>Cd. The abundance patterns of heavy metals in leaf, petiole and root were Cd>Cu>Pb>Zn. Microbial load in rhizosphere of Nymphea pubescens ranged from 93×102 to 69×103 and that of sediment was 62×102 to 125×103. Bacterial load in rhizosphere was higher than that of growing sediment. Four bacterial genera were identified from the rhizosphere of Nymphaea pubescens which include Acinetobacter, Alcaligens, Listeria and Staphylococcus. Acinetobacter, Alcaligens and Listeria are the three bacterial genera isolated from sediment samples. Copper resistance studies of the 14 bacterial isolates from rhizosphere and 7 strains from sediment samples revealed that most of them showed low resistance (<100 μg/ml and very few isolates showed high resistance of 400-500 μg/ml.

Decolorization and detoxification of reactive industrial dyes by immobilized fungi Trametes pubescens and Pleurotus ostreatus

Czech Academy of Sciences Publication Activity Database

Caiseri, L.; Varese, G.C.; Anastasi, A.; Prigione, V.; Svobodová, Kateřina; Marchisio, V.F.; Novotný, Čeněk

2008-01-01

Roč. 53, č. 1 (2008), s. 44-52 ISSN 0015-5632 R&D Projects: GA AV ČR IAA6020411 Institutional research plan: CEZ:AV0Z50200510 Keywords : decolorization * detoxification * trametes pubescens Subject RIV: EE - Microbiology, Virology Impact factor: 1.172, year: 2008

Variability of BVOC emissions from a Mediterranean mixed forest in southern France with a focus on Quercus pubescens

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Genard-Zielinski, A.-C.; Boissard, C.; Fernandez, C.; Kalogridis, C.; Lathière, J.; Gros, V.; Bonnaire, N.; Ormeño, E.

2015-01-01

We aimed at quantifying biogenic volatile organic compound (BVOC) emissions in June from three Mediterranean species located at the O3HP site (southern France): Quercus pubescens, Acer monspessulanum and C. coggygria (for isoprene only). As Q. pubescens was shown to be the main BVOC emitter with isoprene representing ≈ 99% of the carbon emitted as BVOC, we mainly focused on this species. C. coggygria was found to be a non-isoprene emitter (no other BVOCs were investigated). To fully understand both the canopy effect on Q. pubescens isoprene emissions and the inter-individual variability (tree to tree and within canopy), diurnal variations of isoprene were investigated from nine branches (seven branches located to the top of canopy at ≈ 4 m above ground level (a.g.l.), and two inside the canopy at ≈ 2 m a.g.l.). The Q. pubescens daily mean isoprene emission rate (ERd) fluctuated between 23 and 98 μgC gDM-1 h-1. Q. pubescens daily mean net assimilation (Pn) ranged between 5.4 and 13.8, and 2.8 and 6.4 μmol CO2 m-2 s-1 for sunlit and shaded branches respectively. Both ERd and isoprene emission factors (Is), assessed according to Guenther et al. (1993) algorithm, varied by a factor of 4.3 among the sunlit branches. While sunlit branches ERd was clearly higher than for shaded branches, there was a non-significant variability of Is (59 to 77 μgC gDM-1 h-1). Diurnal variations of isoprene emission rates (ERs) for sunlit branches were also investigated. ERs were detected at dawn 2 h after Pn became positive and were mostly exponentially dependent on Pn. Diurnal variations of ERs were not equally well described throughout the day by temperature (CT) and light (CL) parameters according to G93 algorithm. Temperature had more impact than photosynthetically active radiation (PAR) on the morning emissions increase, and ER was no longer correlated to CL × CT between solar noon (maximum ER) and mid-afternoon, possibly due to thermal stress of the plant. A comparison

[Fitness of sexual reproduction of Toona ciliata var. pubescens natural populations and their sexual reproduction and regeneration].

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Huang, Hong Lan; Zhang, Lu; Jia, Li Ming; Liang, Yue-Long; Cai, Jun Huo

2018-04-01

To examine the reproduction fitness coefficients and individual-level fitness of Toona ciliata var. pubescens, their sexual reproduction and natural regeneration were investigated during 2006-2016, with four natural populations in Jiulianshan National Reserve as test objects. The results showed that there were only 2-10 trees for the natural populations of T. ciliata var. pubescens with a small initial number of fruiting plants (3-9 trees), which were from the initial fruiting plants or their first/second generation. The sexual reproduction of these isolated populations were significantly different, and their seed production capacities tended to decline over time. With the maturing of communities, soil seed banks and seed germinations were extremely poor, and the number of trees that could be growing to mature stage was nearly zero. The optimum maturity age of T. ciliata var. pubescens was about 40 a, and the fitness coefficients (2.0-2.8) rapidly increased in early development stage, but then was sharply reduced (0.3-0.5), and then gradually dropped to almost 0. There were significant differences in the fitness at individual level (0-14 tree·cm -2 ) among different populations, but their values were low (close to zero). Based on the existing reproduction rate, the actual values of sexual reproduction and regeneration fitness were much lower than the predicted ones. Due to the low level of genetic fitness, the sexual reproductive ability of different populations all showed decreasing trends. The natural sexual regeneration ability tended to decline, while the fitness of T. ciliata var. pubescens further decreased. All those factors suggested higher investment risks. Therefore, the systems of sexual reproduction became unbalanced and deteriorating. We proposed that more studies, including breeding mating, pollination, seed setting, and genetic diversity evaluation, are needed. Moreover, we should provide suitable forest environment through cleaning up litter in the

Estabelecimento de Eriotheca pubescens (Bombacaceae por meio de semeadura direta e de mudas em cascalheira

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Clarêt Carrijo

2009-09-01

Full Text Available This study analyzed the arboreal specie Eriotheca pubescens ( Mart. Former Zucc. Schoutt & Endler. The main objective was to evaluate whether the seed’s performance, seedling production and field`s plantation, through direct sowing, with and without physical protection to develop the recovery of a degraded area that was explored as a gravel mine, at Água Limpa farm, from UnB (University of Brasilia – Brazil. The specie studied indicated that the seeds have neutral photoblastism and about 5.85% of humidity. The laboratory study indicated vermiculite as the most successfully substratum associated with no shading and temperature condition of 25ºC (77 F. The germination percentage increased after 171 days, indicating a great survival index. There was about 76.5% of survival seedlings that were planted in the field. The specie Eriotheca pubescens has a great potential to be used for restoring degraded areas, especially at the heterogeneous plantation.

Isoprene emission rates and fluxes measured above a Mediterranean oak ( Quercus pubescens) forest

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Simon, V.; Dumergues, L.; Bouchou, P.; Torres, L.; Lopez, A.

2005-03-01

The present work, carried out as part of the European fiEld experimentS to COnstrain Models of atmospheric Pollution and Transport of Emissions project (ESCOMPTE), brings a new contribution to the inventory of the main natural hydrocarbons sources that are liable to participate in the production of ozone. The measurement campaign was conducted in Montmeyan, a site close to Marseilles (France), with the aim of quantifying the terpenic emission pattern and the behaviour of Quercus pubescens, an important Mediterranean tree species. Biogenic emissions by Q. pubescens were determined by the enclosure of an intact branch of this tree in a Teflon cuvette. The total monoterpenic emission rates thus recorded were found to reach maximum values ranged between 40 and 350 μg g Dry Weight-1 h -1. Emissions were correlated strongly with leaf temperature and Photosynthetic Active Radiation (PAR). The fluxes were also determined by extrapolating the results of the enclosure method and by using aerodynamic gradient method. They reach around 73 mg m -2 h -1 with the first method and 55 mg m -2 h -1 with the second one. The obtained values fit with a maximal ratio of 2.

Water extractable phytochemicals from Capsicum pubescens (tree pepper) inhibit lipid peroxidation induced by different pro-oxidant agents in brain

International Nuclear Information System (INIS)

Oboh, G.; Rocha, J.B.T.

2006-03-01

Reactive oxygen species (ROS) is the cause of neurodegenerative disorders such as Lou Gehrig's disease, Parkinson's disease and Huntington's disease; one practical way to prevent and manage neurodegenerative diseases is through the eating of food rich in antioxidants (dietary means). In this study, the antioxidant and neuroprotective properties of aqueous extract of ripe and unripe Capsicum pubescens (popularly known as tree pepper) on different pro-oxidant induced lipid peroxidation in Rat's brain (in vitro) is been investigated. Aqueous extract of freshly harvested pepper was prepared, and the total phenol content, vitamin C, ferric reducing antioxidant property (FRAP) and Fe (II) chelating ability was determined. In addition, the ability of the extracts to protect the Rat's brain against some pro-oxidant FeSO 4 , Sodium nitroprusside and Quinolinic acid) - induced oxidative stress was also determined. The results of the study revealed that ripe Capsicum pubescens had a significantly higher (P 2 O 2 induced decomposition of deoxyribose. Therefore, ripe and unripe Capsicum pubescens would inhibit lipid peroxidation in vitro. However, the ripe potent was a more potent inhibitor of lipid peroxidation, which is probably due to its higher vitamin C and phenol content, reducing power and Fe (II) chelating ability. (author)

Efikasi Asap Cair dari Kayu Laban (Vitex pubescens terhadap Rayap Coptotermes curvignathus

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HA Oramahi

2014-03-01

Full Text Available ABSTRACT Efficacy of liquid smoke from laban wood (Vitex pubescens against Coptotermes curvignathus. Antitermitic activities of liquid smoke produced from Vitex pubescens against C. curvignathus was evaluated in this study. This research was conducted in two steps, i.e. pyrolisis of liquid smoke and efficacy test of liquid smoke as antitermite. Three kinds of liquid smoke were produced at three different pyrolysis temperatures, i.e.  350 oC, 400 oC and 450 oC. Termiticidal activity was evaluated by a no-choice test.  The research indicates that concentration of liquid smoke and pyrolysis temperatures significantly affected  termite mortality and mass losses of the filter paper. The relationship between the concentration of liquid smoke (X and termite mortality (Y at 350 oC, 400 oC,  and  450 oC were Y = 31,4 + 11,76X,  (r2 = 0,60,  Y = 30 + 11,86X (r2 = 0,59,  and Y = 26,66 + 7,6X (r2 = 0,429. The relationship between concentration of liquid smoke (X and mass losses (Y at 350 oC,  400 oC, and 450 oC were Y= 85,12 -3,188X (r2 = 0,723, Y= 88,06 – 3,435X + (r2 = 0,953 and Y= 91,56 – 3,867X  (r2 = 0,886.

Sesquiterpenes and other constituents from leaves of Pterodon pubescens Benth (Leguminosae); Sesquiterpenos e outros constituintes das folhas de Pterodon pubescens Benth (Leguminosae)

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Miranda, Mayker Lazaro Dantas; Garcez, Fernanda Rodrigues; Garcez, Walmir Silva, E-mail: walmir.garcez@ufms.br [Universidade Federal de Mato Grosso do Sul (UFMS), Campo Grande, MS (Brazil). Instituto de Quimica; Abot, Alfredo Raul [Universidade Estadual de Mato Grosso do Sul (UEMS), Aquidauana, MS (Brazil)

2014-05-15

In addition to β-sitosterol, stigmasterol, phaeophitin A, luteolin, kaempferol, quercetin, (+)-catechin, quercetin-3-O-α-L-rhamnopyranoside, rutin, and p-hydroxy-benzoic acid, six known sesquiterpenes, namely (rel)-2β,6β-epoxy-5β-hydroxy-isodaucane, oplopanone, 1β,6α-dihydroxy-4(15)-eudesmene, caryophyllene oxide, α-cadinol, and spathulenol, were isolated from the leaves of Pterodon pubescens (Leguminosae) growing in the Cerrado of Mato Grosso do Sul, Brazil. The (rel)-2β,6β-epoxy-5β-hydroxy-isodaucane corresponds to the correct structure of homalomenol D. The sesquiterpene oplopanone, which bears a modified cadinane skeleton, is being reported for the first time in this genus. The structures of the compounds were determined on the basis of spectral data (MS, IR, and NMR-1D and 2D) and subsequent comparison with data reported in the literature. (author)

Potential of two submontane broadleaved species (Acer opalus, Quercus pubescens) to reveal spatiotemporal patterns of rockfall activity

Science.gov (United States)

Favillier, Adrien; Lopez-Saez, Jérôme; Corona, Christophe; Trappmann, Daniel; Toe, David; Stoffel, Markus; Rovéra, Georges; Berger, Frédéric

2015-10-01

Long-term records of rockfalls have proven to be scarce and typically incomplete, especially in increasingly urbanized areas where inventories are largely absent and the risk associated with rockfall events rises proportionally with urbanization. On forested slopes, tree-ring analyses may help to fill this gap, as they have been demonstrated to provide annually-resolved data on past rockfall activity over long periods. Yet, the reconstruction of rockfall chronologies has been hampered in the past by the paucity of studies that include broadleaved tree species, which are, in fact, quite common in various rockfall-prone environments. In this study, we test the sensitivity of two common, yet unstudied, broadleaved species - Quercus pubescens Willd. (Qp) and Acer opalus Mill. (Ao) - to record rockfall impacts. The approach is based on a systematic mapping of trees and the counting of visible scars on the stem surface of both species. Data are presented from a site in the Vercors massif (French Alps) where rocks are frequently detached from Valanginian limestone and marl cliffs. We compare recurrence interval maps obtained from both species and from two different sets of tree structures (i.e., single trees vs. coppice stands) based on Cohen's k coefficient and the mean absolute error. A total of 1230 scars were observed on the stem surface of 847 A. opalus and Q. pubescens trees. Both methods yield comparable results on the spatial distribution of relative rockfall activity with similar downslope decreasing recurrence intervals. Yet recurrence intervals vary significantly according to tree species and tree structure. The recurrence interval observed on the stem surface of Q. pubescens exceeds that of A. opalus by > 20 years in the lower part of the studied plot. Similarly, the recurrence interval map derived from A. opalus coppice stands, dominant at the stand scale, does not exhibit a clear spatial pattern. Differences between species may be explained by the bark

Efeito de extratos naturais de folhas vegetais em Leucoagaricus gongylophorus (Möller Singer, (Agaricales: Agaricaceae / Effect of natural extracts of vegetable leaves in Leucoagaricus gongylophorus (Möller Singer, (Agaricales: Agaricaceae

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Marcelo Dias Souza

2011-12-01

Full Text Available O estudo teve como objetivo avaliar os efeitos dos extratos naturais, à base de folhas de diferentes espécies vegetais, em Leucoagaricus gongylophorus, fungo simbionte de formigas cortadeiras. O experimento foi realizado no Laboratório de Proteção Florestal, da Faculdade de Engenharia Florestal, da Universidade Federal de Mato Grosso, sob temperatura média 26 ± 2ºC, e umidade relativa de 70 ± 10%. Os tratamentos avaliados foram os extratos aquosos a 10% (peso/volume de dez diferentes espécies vegetais. Foram realizados onze tratamentos, sendo que para cada um foi utilizado um recipiente de 1,5 l de volume, colocado na parte central contendo fungo e formigas, no qual era interligado com mais dois recipientes, de igual volume, interligados entre si por um tubo plástico, propiciando condições necessárias para que as formigas desenvolvessem suas atividades normais. O fungo e as formigas cortadeiras, após coletados, foram transferidos para os recipientes em laboratório. Assim que os formigueiros artificiais apresentavam atividades normais, os extratos foram adicionados diretamente sobre o fungo, com exceção da testemunha. Os tratamentos que tiveram efeito deletério sobre o fungo, em ordem decrescente foram os à base de Tabebuia vellosoi (ipê-amarelo-liso, Azadirachta indica (Nim, Magonia pubescens (Timbó, Annona reticulata (Pinha e Amburana acreana (cerejeira.AbstractThe objective of this study was to evaluate the effects of natural extracts of leaves of different plant species, in Leucoagaricus gongylophorus, symbiotic fungus of leaf-cutting ants. The experiment was conducted at the Laboratory of Forest Protection, Federal University from Mato Grosso, on average temperature 26 ± 2º C and relative humidity of 70 ± 10%. The treatments evaluated were the aqueous extracts of 10% (weight/volume of ten different plant species. It was carried out 11 treatments, and for each one a container of 1.5 l volume was used, placed in the

Sesquiterpenes and other constituents from leaves of Pterodon pubescens Benth (Leguminosae)

International Nuclear Information System (INIS)

Miranda, Mayker Lazaro Dantas; Garcez, Fernanda Rodrigues; Garcez, Walmir Silva

2014-01-01

In addition to β-sitosterol, stigmasterol, phaeophitin A, luteolin, kaempferol, quercetin, (+)-catechin, quercetin-3-O-α-L-rhamnopyranoside, rutin, and p-hydroxy-benzoic acid, six known sesquiterpenes, namely (rel)-2β,6β-epoxy-5β-hydroxy-isodaucane, oplopanone, 1β,6α-dihydroxy-4(15)-eudesmene, caryophyllene oxide, α-cadinol, and spathulenol, were isolated from the leaves of Pterodon pubescens (Leguminosae) growing in the Cerrado of Mato Grosso do Sul, Brazil. The (rel)-2β,6β-epoxy-5β-hydroxy-isodaucane corresponds to the correct structure of homalomenol D. The sesquiterpene oplopanone, which bears a modified cadinane skeleton, is being reported for the first time in this genus. The structures of the compounds were determined on the basis of spectral data (MS, IR, and NMR-1D and 2D) and subsequent comparison with data reported in the literature. (author)

Water extractable phytochemicals from Capsicum pubescens (tree pepper) inhibit lipid peroxidation induced by different pro-oxidant agents in brain

Energy Technology Data Exchange (ETDEWEB)

Oboh, G [Biochemistry Department, Federal University of Technology, Akure, Ondo State (Nigeria); [Departamento de Quimica, Universidade Federal de Santa Maria (UFSM), Campus Universitario - Camobi, Santa Maria RS (Brazil); [Abdus Salam International Centre for Theoretical Physics, Trieste (Italy)]. E-mail: goboh2001@yahoo.com; Rocha, J B.T. [Campus Universitario - Camobi, Santa Maria RS (Brazil)

2006-03-15

Reactive oxygen species (ROS) is the cause of neurodegenerative disorders such as Lou Gehrig's disease, Parkinson's disease and Huntington's disease; one practical way to prevent and manage neurodegenerative diseases is through the eating of food rich in antioxidants (dietary means). In this study, the antioxidant and neuroprotective properties of aqueous extract of ripe and unripe Capsicum pubescens (popularly known as tree pepper) on different pro-oxidant induced lipid peroxidation in Rat's brain (in vitro) is been investigated. Aqueous extract of freshly harvested pepper was prepared, and the total phenol content, vitamin C, ferric reducing antioxidant property (FRAP) and Fe (II) chelating ability was determined. In addition, the ability of the extracts to protect the Rat's brain against some pro-oxidant FeSO{sub 4}, Sodium nitroprusside and Quinolinic acid - induced oxidative stress was also determined. The results of the study revealed that ripe Capsicum pubescens had a significantly higher (P<0.05) total phenol [ripe (113.7mg/100g), unripe (70.5mg/100g)] content and ferric reducing antioxidant property than the unripe pepper. However, there was no significant difference in the vitamin C [ripe (231.5{mu}g/g), unripe (224.4{mu}g/g)] content and Fe (II) chelating ability. Furthermore, the pepper extracts caused a significant decrease (P<0.05) in 25{mu}M Fe(II), 7{mu}M Sodium Nitroprusside and 1mM Quinolinic acid induced lipid peroxidation in the Rat's brain in a dose-dependent manner. However, the ripe pepper inhibited MDA (Malondialdehyhide) production in the Rat's brain than the unripe pepper. Conversely, both extract did not significantly inhibit Fe (II)/H{sub 2}O{sub 2} induced decomposition of deoxyribose. Therefore, ripe and unripe Capsicum pubescens would inhibit lipid peroxidation in vitro. However, the ripe potent was a more potent inhibitor of lipid peroxidation, which is probably due to its higher vitamin C and phenol content, reducing power and Fe

Growth response of downy birch (Betula pubescens) to moisture treatment at an cut-over peat bog in the Šumava Mts., Czech Republic

Czech Academy of Sciences Publication Activity Database

Lanta, Vojtěch; Hazuková, I.

2005-01-01

Roč. 42, - (2005), s. 247-256 ISSN 0003-3847 R&D Projects: GA ČR GD206/03/H034 Institutional research plan: CEZ:AV0Z6005908 Keywords : Betula pubescens * cut-over peatland * increment Subject RIV: EF - Botanics Impact factor: 0.315, year: 2005

Sesquiterpenos e outros constituintes das folhas de Pterodon pubescens Benth (Leguminosae

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Mayker Lazaro Dantas Miranda

2014-06-01

Full Text Available In addition to β-sitosterol, stigmasterol, phaeophitin A, luteolin, kaempferol, quercetin, (+-catechin, quercetin-3-O-α-L-rhamnopyranoside, rutin, and p-hydroxy-benzoic acid, six known sesquiterpenes, namely (rel-2β,6β-epoxy-5β-hydroxy-isodaucane, oplopanone, 1β,6α-dihydroxy-4(15-eudesmene, caryophyllene oxide, α-cadinol, and spathulenol, were isolated from the leaves of Pterodon pubescens (Leguminosae growing in the Cerrado of Mato Grosso do Sul, Brazil. The (rel-2β,6β-epoxy-5β-hydroxy-isodaucane corresponds to the correct structure of homalomenol D. The sesquiterpene oplopanone, which bears a modified cadinane skeleton, is being reported for the first time in this genus. The structures of the compounds were determined on the basis of spectral data (MS, IR, and NMR-1D and 2D and subsequent comparison with data reported in the literature.

DNA typing of birch: Development of a forensic STR system for Betula pendula and Betula pubescens.

Science.gov (United States)

Wesselink, Monique; Dragutinović, Aleksandar; Noordhoek, Jeroen W; Bergwerff, Leonie; Kuiper, Irene

2018-04-07

Although botanical trace evidence is often encountered in case investigations, the utilization of such traces in forensic investigations is still limited. Development of a forensic STR system for the two species of Betula (birch) indigenous to and abundant in North West Europe is a step in enhancing the applicability of traces from these species. We describe six microsatellite markers developed for birch species in detail, including repeat structure, and we propose a nomenclature for the encountered alleles. To assess the population characteristics, the genetic composition of wild, planted and intermediate populations of Betula pendula (a diploid species) and Betula pubescens (a tetraploid species) were investigated. The genetic differences between these two species were larger than the differences between populations of one species, even when both species co-occurred at one location. Therefore allele frequencies were estimated for both species separately. General, conservative random match probabilities were estimated for wild trees based on these allele frequencies (5∙10 -6 for the diploid B. pendula and 1∙10 -13 for the tetraploid B. pubescens), illustrating the potential relevance if trace evidence secured from a suspect is found to match a birch tree growing on or near a crime scene. Apart from wild trees, planted Betula trees also occur that may not originate from seeds, but may have been propagated through cloning. Based on the studied Betula trees, the random match probability of a potentially planted profile might be as high as 1.4∙10 -2 . Copyright © 2018 Elsevier B.V. All rights reserved.

Improved Laccase Production by Trametes pubescens MB89 in Distillery Wastewaters

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P. J. Strong

2011-01-01

Full Text Available Various culture parameters were optimised for laccase synthesis by Trametes pubescens MB89, including pH, carbon source, nitrogen source, lignocellulosic supplements, and reported inducers. Glucose, in conjunction with a complex nitrogen source at pH 5.0, resulted in the highest laccase yield. Adding ethanol, copper, or 2,5-xylidine prior to inoculation further improved laccase concentrations. The addition of 2,5-xylidine was further investigated with multiple additions applied at varying times. This novel application substantially improved laccase production when applied regularly from inoculation and during the growth phase, and also countered glucose repression of laccase synthesis. Single and multiple factor changes were studied in three distillery wastewaters and a wine lees. A synergistic increase in laccase synthesis was observed with the addition of glucose, copper, and 2,5-xylidine. Single addition of 2,5-xylidine proved most beneficial with distillery wastewaters, while copper addition was most beneficial when using the wine lees as a culture medium.

Stable isotope investigations from tree rings (Betula pubescens) in Northern Iceland

International Nuclear Information System (INIS)

Bertler, N.A.N.; Rose, J.J.; Mattey, D.P.; Brownlees, M.; Stoetter, J.E.

1999-01-01

Stable isotope investigations from recent trees (Betual pubescens) from two different locations in Northern Iceland have been carried out to examine applicability for paleoclimatic research. The aim was to correlate oxygen and carbon isotope data of annual and three year resolution derived from individual rings with meteorological data, in order to establish a calibration function for fossil wood samples. A precise dendrochronological record has been established for all cores to permit a direct comparison between different data sets. The material used for the isotopic analysis is pure α-cellulose. The oxygen and carbon ratios were measured using a new technique, employing CO with continuous flow mass spectrometry. As this method does not allow a simultaneous measurements of the carbon ratios, the δ 13 C values have been analysed separately, using CO 2 . Both methods demonstrated their reliability through high precision and accuracy in the values for the measured standards. However there is little confidence in the sample data, as they suffer from poor precision and non-consistency

Intraspecific variation of Bothrops pubescens (cope, 1869 venom in Uruguay (serpentes: viperidae

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V. Morais

2006-01-01

Full Text Available In Uruguay, there was no information about the variations degree in Bothrops pubescens venoms until the present work, in which we investigated intraspecific venom variation using polyacrylamide gel electrophoresis (SDS-PAGE. We found some differences in the venom protein profile; however, they were not related to the parameters studied (geographic distribution, weight, sex, and captivity time. Moreover, we distinguished two different groups in relation to band densities at 49 and 57 kDa. Specimens with predominant density in the 49kDa band tend to be predominantly females. Weight distribution in this group extended for all the range (150-1500 g with an average weight of 720 g. The other group (57kDa predominant band showed restricted weight range (150-400 g with an average weight of 280 g. Cluster analysis was also performed. The variability observed in the venom profile probably corresponds to genetic variations.

Arboreal component, phytosociology structure and environmental relations in a remnant of cerradão, Curvelo - MG

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Thiago José Ornelas Otoni

2013-06-01

Full Text Available This work aimed to verify the existence of variations in composition and distribution of tree species due to soil characteristics in a fragment of dystrophic savanna in Curvelo-MG. On description in the compartment of the phanerophytes of this plant community, were installed ten permanent plots with 1.000 m2 (20 x 50 m with fixed distances of 100 m between each plot. All alive individuals that had diameter at soil height (DSH - diameter to 0.3 m from ground level > 5.0 cm were sampled. The Individuals with multiple boles were sampled when the value of square root of the sum-square of DSH had been greater than criterion of the inventory. Were collected Soil samples at two depths (0-20 e 20-40 cm and was measured the distances of plots of a watercourse. To study the community were generated ordination diagrams of plots, species and environmental variables by means of a canonical correspondence analysis (CCA. The richness sampled was 92 species, 36 families and 74 genera, Erythroxylum, Byrsonima, Myrcia and Qualea. Jackknife estimators (first and second order designed a wealth of 106.4 and 107.8 species. The species Magonia pubescens, Terminalia argentea, Annona crassiflora, Eugenia dysenterica e Xylopia aromatica were distribuited underneath the environmental gradient.

Alkali extraction and physicochemical characterization of hemicelluloses from young bamboo (Phyllostachys pubescens Mazel

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Qiang Luo

2012-11-01

Full Text Available Two hemicellulose fractions were obtained by extraction of one-month- old young bamboo (Phyllostachys pubescens Mazel. The fractionation procedure employed 2% NaOH as extractant, followed by filtration, acidification, precipitation, and washing with 70% ethanol solution. The total yield was 26.2%, based on the pentosan content in bamboo. The physicochemical properties were determined and sugar composition analysis showed that the hemicelluloses consisted mainly of xylose, arabinose, galactose, and a small amount of uronic acid. Furthermore, based on FT-IR and NMR spectra analyses, the structure of hemicelluloses was determined to be mainly arabinoxylans linked via (1→4-β-glycosidic bonds with branches of arabinose and 4-O-methyl-D-glucuronic acid. The molecular weights were 6387 Da and 4076 Da, corresponding to the hemicelluloses HA and HB. Finally, the thermal stability was elucidated using the TG-DTG method. The obtained results can provide important information for understanding young bamboo and the hemicelluloses in it.

Evaluation of antioxidative and antidiabetic activity of bark of holarrhena pubescens wall.

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Bhusal, Anup; Jamarkattel, Nirmala; Shrestha, Aasmin; Lamsal, Nisha Kiran; Shakya, Sangam; Rajbhandari, Sneha

2014-09-01

The objectives of the study are to screen out various phytochemicals and to evaluate the antioxidant and antidiabetic potential of the stem bark of Holarrhena pubescens Wall (Holarrhena antidysenterica). The antioxidant activity was determined by the DPPH (2,2-diphenyl-1-picrylhydrazyl) radical scavenging activity where ascorbic acid was taken as positive control. The antioxidant property was later exploited and the methanolic extract of plant was tested for antihyperglycemic activity in glucose overloaded hyperglycemic mice. The extract was tested for its hypoglycemic activity at two-dose levels, 250 and 500 mg/kg respectively where Glipizide 5 mg/kg was taken as standard reference drug. All results are presented as mean ± SD (Standard Deviation). Significant differences between experimental groups were determined by Student's t-test. The methanolic and water extract showed strong antioxidant activity with inhibition of more than 90% DPPH free radicals at the concentration of 100μg/mL. The hypoglycemic activity of methanolic extract on glucose tolerance test were significant (p flavonoides, phenolic compounds suggested that they may be partially responsible for antioxidant and antidiabetic activity.

Quantitative Analysis of Ca, Mg, and K in the Roots of Angelica pubescens f. biserrata by Laser-Induced Breakdown Spectroscopy Combined with Artificial Neural Networks

Science.gov (United States)

Wang, J.; Shi, M.; Zheng, P.; Xue, Sh.; Peng, R.

2018-03-01

Laser-induced breakdown spectroscopy has been applied for the quantitative analysis of Ca, Mg, and K in the roots of Angelica pubescens Maxim. f. biserrata Shan et Yuan used in traditional Chinese medicine. Ca II 317.993 nm, Mg I 517.268 nm, and K I 769.896 nm spectral lines have been chosen to set up calibration models for the analysis using the external standard and artificial neural network methods. The linear correlation coefficients of the predicted concentrations versus the standard concentrations of six samples determined by the artificial neural network method are 0.9896, 0.9945, and 0.9911 for Ca, Mg, and K, respectively, which are better than for the external standard method. The artificial neural network method also gives better performance comparing with the external standard method for the average and maximum relative errors, average relative standard deviations, and most maximum relative standard deviations of the predicted concentrations of Ca, Mg, and K in the six samples. Finally, it is proved that the artificial neural network method gives better performance compared to the external standard method for the quantitative analysis of Ca, Mg, and K in the roots of Angelica pubescens.

Two new triterpene saponins from the anti-inflammatory saponin fraction of Ilex pubescens root.

Science.gov (United States)

Wang, Jing-Rong; Zhou, Hua; Jiang, Zhi-Hong; Liu, Liang

2008-07-01

The saponin fraction from the ethanolic extracts of the root of Ilex pubescens Hook. et Arn. (Ilexaceae) was found to exhibit potent anti-inflammatory effects on carrageenan-induced paw edema in rats. Two novel triterpene saponins, pubescenosides C and D (1 and 2, resp.), together with five known saponins were isolated from this saponin fraction. The structures of 1 and 2 were elucidated as (20beta)-3-O-[beta-D-glucopyranosyl-(1-->2)-beta-D-xylopyranosyl]ursa-12,18-dien-28-oic acid 28-O-beta-D-glucopyranosyl ester, and (20beta)-3-O-[alpha-L-rhamnopyranosyl-(1-->2)-beta-D-glucopyranosyl-(1-->2)-beta-D-xylopyranosyl]ursa- 12,18-dien-28-oic acid 28-O-beta-D-glucopyranosyl ester, respectively, on the basis of chemical and spectroscopic data. Five known saponins isolated from the saponin fraction were identified as ilexsaponin B(1), B(2), B(3), A(1), and chikusetsusaponin IV(a).

Metabolomic Profiling of the Nectars of Aquilegia pubescens and A. Canadensis.

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Christos Noutsos

Full Text Available To date, variation in nectar chemistry of flowering plants has not been studied in detail. Such variation exerts considerable influence on pollinator-plant interactions, as well as on flower traits that play important roles in the selection of a plant for visitation by specific pollinators. Over the past 60 years the Aquilegia genus has been used as a key model for speciation studies. In this study, we defined the metabolomic profiles of flower samples of two Aquilegia species, A. Canadensis and A. pubescens. We identified a total of 75 metabolites that were classified into six main categories: organic acids, fatty acids, amino acids, esters, sugars, and unknowns. The mean abundances of 25 of these metabolites were significantly different between the two species, providing insights into interspecies variation in floral chemistry. Using the PlantSEED biochemistry database, we found that the majority of these metabolites are involved in biosynthetic pathways. Finally, we explored the annotated genome of A. coerulea, using the PlantSEED pipeline and reconstructed the metabolic network of Aquilegia. This network, which contains the metabolic pathways involved in generating the observed chemical variation, is now publicly available from the DOE Systems Biology Knowledge Base (KBase; http://kbase.us.

Pterodon pubescens Benth: stability study of microencapsulated extract and isolated compounds monitored by antinociceptive assays

International Nuclear Information System (INIS)

Servat, Leila; Spindola, Humberto M.; Carvalho, Joao E. de; Foglio, Mary A.; Rodrigues, Rodney A.F.; Sousa, Ilza M.O.; Ruiz, Ana L.T.G.

2012-01-01

Pterodon pubescens Benth. (Pp) seeds, commercially available in Brazil, are used in folk medicine in anti-inflammatory, analgesic, and anti-rheumatic preparations. The present study demonstrated the antinociceptive properties of isomers 6a-hydroxy-7β-acetoxy-vouacapan-17β--oate methyl ester and 6a-acetoxy-7β-hydroxy-vouacapan-17β-oate methyl ester (C1), isolated from (Pp), employing different experimental models. A stability study was performed to investigate the relationship of microencapsulation by spray-drying on the maintenance of antinociceptive action. Therefore, C1 and Pp extract samples were monitored in accelerated stability study, evaluating both microencapsulated and non-microencapsulated samples. It was observed that sample C1 possess antinociceptive activity revealed by writhing and formalin tests; C1 showed significantly anti-allodynic, but not ntihyperalgesic effect; the microencapsulation maintained the activity and integrity of both, sample C1 and Pp crude extract; microencapsulation by spray drying is a useful alternative to increase shelf life. (author)

Sweat control in male by the use of alunogen and cypripedium pubescens

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Lorenzo Martini

2015-01-01

Full Text Available Aim of my study is to investigate upon the quality and quantity of the free fatty acids secreted by apocrine glands, as chief index to determine the real efficacy of a new model of antiperspirant-deodorant, that interferes directly with apocrine glands (by reducing drastically the secretion of free fatty acids and indirectly with eccrine glands, by minimising the salted water secretion. I created an innovative cosmetic formula that comprises the Alunogen, idest the heptadecahydrated form of aluminium sulphate, since the generic aluminium sulphate has been recently accused of the onset of the Alzheimer’s disease, when penetrating the epidermis, although definitive scientific proof is difficult to establish due to the lack of longitudinal studies, and therefore could be banished in the very next future. The formula comprises also the concrète of Cypripedium Pubescens (Lady’s slipper which contains, inter alia, the cypripedin, a quinine-analog, endowed by anticholinergic activities, that can be reputed useful as astringent agent with regards to eccrine glands, synergically to the action upon apocrine glands performed by alunogen. I recruited 11 young men, 11 bricklayers that customarily have to work 9 hours pro day after the hot summer sun and assert without doubt to sweat copiously, in order to carry out my experience.

Effect of postharvest temperature on the shelf life of gabiroba fruit (Campomanesia pubescens

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Edson Pablo da Silva

2013-12-01

Full Text Available The objective of this study was to determine the optimal temperature for storing gabiroba fruit (Campomanesia pubescens without affecting compounds' quality. The fruits were stored at different temperatures (0 ºC, 6 ºC, 12 ºC, and 20 ºC and the effect on the pH, total titratable acidity, soluble solids, total sugars, vitamin C, and antioxidant components such as tannins and total phenolic compounds was evaluated. It was observed an increase in the pH and total titratable acidity during storage at all the temperatures tested. Gabiroba fruits were stored for 9 and 3 days at 12 ºC and 20 ºC, respectively, and under both temperatures they showed a reduction in tannins and an increase in vitamin C content. As gabirobas armazenadas a 0º and 6 ºC alcançaram maior tempo de armazenamento After 12 days of storage, the fruits stored at 6 ºC contained higher amounts of water soluble solids, sugars, and antioxidants. In general, for long term storage, it is suggested to store gabiroba fruits at 6 ºC. On the other hand, for short term storage, the temperature of 12 ºC would be the better to keep high levels of vitamin C and phenolic compounds.

Drought impact on Quercus pubescens Willd. isoprene emissions over the Mediterranean area: what future?

Science.gov (United States)

Cyrielle Genard-Zielinski, Anne; Boissard, Christophe; Ormeño, Elena; Lathière, Juliette; Guenet, Bertrand; Gauquelin, Thierry; Fernandez, Catherine

2015-04-01

Biogenic Volatile Organic Compounds (BVOCs) released by plants mostly originate from their secondary metabolism. Their emissions are modulated, in terms of intensity and molecule diversity, by environmental conditions. Among BVOCs, isoprene has been especially studied due to its high emission fluxes and its contribution to tropospheric photochemistry, both in the gaseous and particulate phases. However, the way isoprene emissions are impacted by some abiotic factors, especially water stress, is still under debate. In a world facing climatic changes, global climate models expect air temperature and drought intensity to strengthen in the Mediterranean area by 2100. Our work focuses on the impact of water stress on isoprene emissions (ERiso) from Quercus pubescens Willd. This species covers large areas of the Mediterranean area where it appears to be the main isoprene emitter. An in situ experimentation was performed at the O3HP (Oak Observatory at OHP, southern France) in a pubescent oak forest with trees adapted to long lasting stress periods. We investigated during a whole seasonal cycle (from June 2012 to June 2013) the course of ERiso under both natural water stress (control treatment: C) and intensified water stress (stress treatment: S) by artificially reducing rain by 30% using a specific rain exclusion device. Restricted rain did not modify either the net CO2 assimilation or ERiso during the whole season. However, isoprene emission factors (Is) for trees under S were significantly higher (a factor of ˜ 2) than for trees growing under C in August (137.8 compared to 75.3 μgC.gDM-1.h-1 respectively) and September (75.3 compared to 40.2 μgC.gDM-1.h-1 respectively). Based on our experimental emission database, an appropriate isoprene emission algorithm (GZ2014) was developed using a statistic approach (an artificial neural network). Using ambient and edaphic environmental parameters integrated over up to 3 weeks, GZ2014 was found to represent more than 80% of

Biological Activities and Phytochemical Profiles of Extracts from Different Parts of Bamboo (Phyllostachys pubescens

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Akinobu Tanaka

2014-06-01

Full Text Available Besides being a useful building material, bamboo also is a potential source of bioactive substances. Although some studies have been performed to examine its use in terms of the biological activity, only certain parts of bamboo, especially the leaves or shoots, have been studied. Comprehensive and comparative studies among different parts of bamboo would contribute to a better understanding and application of this knowledge. In this study, the biological activities of ethanol and water extracts from the leaves, branches, outer culm, inner culm, knots, rhizomes and roots of Phyllostachys pubescens, the major species of bamboo in Japan, were comparatively evaluated. The phytochemical profiles of these extracts were tentatively determined by liquid chromatography-mass spectrometry (LC-MS analysis. The results showed that extracts from different parts of bamboo had different chemical compositions and different antioxidative, antibacterial and antiallergic activities, as well as on on melanin biosynthesis. Outer culm and inner culm were found to be the most important sources of active compounds. 8-C-Glucosylapigenin, luteolin derivatives and chlorogenic acid were the most probable compounds responsible for the anti-allergy activity of these bamboo extracts. Our study suggests the potential use of bamboo as a functional ingredient in cosmetics or other health-related products.

Germinación, microinjertación y cultivo de callos in vitro de Vasconcellea stipulata V.M. Badillo y Vasconcellea pubescens A.DC

OpenAIRE

Espinosa Soto, Isabel

2016-01-01

En varias poblaciones rurales de regiones andinas y centroamericanas se utilizan con fines etnomédicos las hojas, el látex y el fruto de las plantas de la familia Caricaceae cuyo miembro más representativo es la papaya (Carica papaya L.), la cual produce la fuente comercial más importante de la enzima proteolítica papaína. El presente trabajo estudia las especies Vasconcellea stipulata V.M. Badillo y Vasconcellea pubescens A.DC que pertenecen al género Vasconcellea, miembros de la familia Car...

Ecophysiological characteristics and cadmium accumulation in Downy Oak (Quercus pubescens Willd.

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Cocozza C

2012-10-01

Full Text Available Heavy metals provoke environmental pollution with potentially toxic effects on human and plants systems. Recently, investigations are conducted on plants that may play a relevant role on pollutants absorption or stabilization, focusing on fast growing tree species in agronomic conditions; little is known on the effects of contaminants on tree species colonizing abandoned fields to be used in restoration ecology. The effects of Cd on photosynthetic performance and metal accumulation were investigated in Quercus pubescens Willd. seedlings grown in pots containing a mixture of sand, clay, turf and Cd-treatments (0, 25 and 75 mg kg-1 dry soil. The studied photosynthetic parameters (Asat= net phytosynthesis; Rday= day respiration; Γcomp= CO2 compensation point; Vcmax= maximum carboxylation rate; Jmax = electron transport rate; TPU = triose phosphate use; Ci/Ca = ratio of intercellular (Ci to ambient (Ca [CO2] (Ci/Ca; Jmax/Vcmax = ratio; (gsmax = maximum stomatal conductance; (lg = stomatal conductance estimated relative to the photosynthetic rate; (Fv/Fm = maximum quantum yield of PSII photochemistry; (ΔF/F’m = effective photochemical efficiency varied progressively with increasing Cd concentration in the soil, highlighting a negative impact on photosynthetic potential and PSII functioning. Approximately 10% of added Cd was found to be extractable from the substrate, at the maximum concentration applied, with about 12 and 0.75 as bioaccumulation and translocation factors, respectively. Analogously, Cd accumulated up to 34, 30 and 46 mg kg−1 in leaves, stem and roots, respectively. While it is not possible to extrapolate from the present study with seedlings to effects on mature pine trees, there are clear implications for regeneration in soils contaminated with heavy metals, which may lead to ecosystem deterioration.

Preparation and characterization of microcapsules of Pterodon pubescens Benth. by using natural polymers

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Alexandre Espada Reinas

2014-12-01

Full Text Available An oleaginous fraction obtained from an alcohol extract of the fruit of Pterodon pubescensBenth. (FHPp was microencapsulated in polymeric systems. These systems were developed using a complex coacervation method and consisted of alginate/medium-molecular-weight chitosan (F1-MC, alginate/chitosan with greater than 75% deacetylation (F2-MC, and alginate/low-molecular-weight chitosan (F3-MC. These developed systems have the potential to both mask the taste of the extract, and to protect its constituents against possible chemical degradation. The influence of the formulation parameters and process were determined by chemical profiling and measurement of the microencapsulation efficiency of the oleaginous fraction, and by assessment of microcapsule morphology. The obtained formulations were slightly yellow, odorless, and had a pleasant taste. The average diameters of the microcapsules were 0.4679 µm (F2-MC, 0.5885 µm (F3-MC, and 0.9033 µm (F1-MC. The best formulation was F3-MC, with FHPp microencapsulation efficiency of 61.01 ± 2.00% and an in vitro release profile of 75.88 ± 0.45%; the content of vouacapans 3-4 was 99.49 ± 2.80%. The best model to describe the release kinetics for F1-MC and F3-MC was that proposed by Higuchi; however, F2-MC release displayed first-order kinetics; the release mechanism was of the supercase II type for all formulations.

Indigenous and inoculated yeast fermentation of gabiroba (Campomanesia pubescens) pulp for fruit wine production.

Science.gov (United States)

Duarte, Whasley Ferreira; Dias, Disney Ribeiro; de Melo Pereira, Gilberto Vinicius; Gervásio, Ivani Maria; Schwan, Rosane Freitas

2009-04-01

The objectives of this study were to evaluate the potential of gabiroba Campomanesia pubescens (DC) O. Berg in the production of a beverage fermented using selected and wild yeasts from indigenous fermentation, analyze the volatile compounds profile present during the process of fermentation, and evaluate the sensory quality of the final beverage produced. Throughout the process of fermentation, when Saccharomyces cerevisiae UFLA CA 1162 was inoculated, there were stable viable populations around 9 log cells ml(-1). During indigenous fermentation, yeast population increased from 3.7 log CFU ml(-1) to 8.1 log CFU ml(-1) after 14 days. The diversity and dynamics of the yeast population during indigenous fermentation observed by PFGE analysis showed five different karyotyping profiles in the first days of fermentation. After the seventh day, there was a higher frequency of a similar S. cerevisiae profile. The yeast non-Saccharomyces were identified by sequencing of the ITS region as Candida quercitrusa and Issatchenkia terricola. Inoculated fermentations yielded a higher amount of alcohol than indigenous ones, indicating the efficiency of selected strains. There was also a greater concentration of higher alcohols, which are usually responsible for the flavor found in alcoholic beverages. Based on the characteristics of the pulp and acceptance in the sensory analysis, gabiroba fruits showed good potential for use in the production of fermented beverage.

Critical electrolyte concentration of chromatin in polytene chromosomes of Trichosia pubescens (Diptera, Sciaridae

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Ana Lúcia P. Monteiro

1998-06-01

Full Text Available The binding of toluidine blue molecules to nucleic acid phosphates under conditions of competition with Mg2+ ions was studied in Trichosia pubescens polytene chromosome regions differing in composition and organization (RNA-rich areas and puffs, DNA puffs, heterochromatin. The aim was to find variability in the Mg2+ concentration at which metachromasy was completely prevented (= critical electrolyte concentration; CEC and that could reflect differences at the level of nucleoprotein complexes in particular chromosome regions and developmental phases. Although high CEC values have been found in tightly packed chromatin such as that of heterochromatin zones, the CEC values for the other regions have proven to be affected not only by availability and proximity of DNA phosphates but also by RNA richness and other factors. Among these, changes in DNA geometry and packing state have been assumed for explaining increased values after RNA removal in DNA puffs and RNA-rich zones. Based on CEC values it has been suggested that alterations at the level of nucleoprotein complexes may occur in puffs before they are morphologically detectable. CEC results for polytene chromosomes were thus revealed to vary considerably with slight variations in nucleoprotein composition and organization. However, since a complex and apparently contradictory rationale has to be used for explaining part of the results, CEC is not recommended as a useful tool for extensive and comparative studies of this particular model.A ligação de moléculas de azul de toluidina a grupamentos fosfatos de ácido nucléico em condições de competição com íons Mg2+ foi estudada em regiões de cromossomos politênicos de Trichosia pubescens que diferem em composição e organização (áreas ricas em RNA, pufes de RNA e DNA, heterocromatina. O objetivo foi encontrar variabilidade na concentração de Mg2+ na qual a metacromasia fosse completamente abolida (= concentração crítica de eletr

Water relations, stomatal response and transpiration of Quercus pubescens trees during summer in a Mediterranean carbon dioxide spring

Energy Technology Data Exchange (ETDEWEB)

Tognetti, R.; Miglietta, F.; Raschi, A. [Consiglio Nazionale della Ricerche, Firenze (Italy); Longobucco, A. [Centro Studi per l`Informatica applicata all`Agricoltura, Firenze (Italy)

1999-04-01

Variations in water relations and stomatal response of downy oak (Quercus pubescens) were analyzed under Mediterranean field conditions during two consecutive summers at two locations characterized by different atmospheric CO{sub 2} concentrations due to the presence of a CO{sub 2} spring at one of the locations. The heat-pulse velocity technique was used to estimate water use during a five-month period from June to November 1994. At the end of the sap flow measurements, the trees were harvested and foliage and sapwood area measured. The effect of elevated CO{sub 2} concentration on leaf conductance was less at high leaf-to-air water vapour pressure difference than at low leaf-to-air water vapour pressure difference. Mean and diurnal sap fluxes were consistently higher in trees at the control site than in the trees at the CO{sub 2} spring site. Results are discussed in terms of effects of elevated CO{sub 2} concentration on plant water use at the organ and whole-tree level. 76 refs., 9 figs.

Evaluation and decontamination of crude oil-polluted soils using Centrosema pubescen Benth and amendment-support options.

Science.gov (United States)

Nwaichi, Eucharia O; Osuji, Leo C; Onyeike, Eugene N

2011-04-01

Growth performance and phytoremediation of soil of the Niger Delta Region of Nigeria artificially-contaminated with crude oil (up to 100 mL/2 kg soil) using centrosema pubescen Benth was investigated for 12 weeks. The soil samples in which the plants were established were either un-amended, or amended with NPK, or UREA or chicken manure. The extents of removal of PAHs and BTEX were measured as well as the rates of growth of the plants. Gas Chromatographic analysis confirmed the degradation of carcinogenic hydrocarbons like BTEXs and PAHs with this technique. At the highest dose of crude, the contaminant concentrations were 43 mg/kg PAHs, 10 mg/kg BTEX, and 5,613 mg/kg O&G. The greatest percent removal of BTEX was observed at the highest contaminant dose, and with the manure amendment. Similar trends were observed with PAHs and although they were less marked, the trends with PAHs may have been more highly statistically significant. There was no measurable plant uptake of contaminants. Inhibition of plant growth (measured as leaf area, shoot length and production of dry weight) was proportional to the dose of crude oil, but the manure amendment was very effective at reducing the growth inhibition. Interestingly, manure amendment reduced the phytotoxicity significantly in this study.

Carotenoids and Carotenoid Esters of Red and Yellow Physalis (Physalis alkekengi L. and P. pubescens L.) Fruits and Calyces.

Science.gov (United States)

Wen, Xin; Hempel, Judith; Schweiggert, Ralf M; Ni, Yuanying; Carle, Reinhold

2017-08-02

Carotenoid profiles of fruits and calyces of red (Physalis alkekengi L.) and yellow (P. pubescens L.) Physalis were characterized by HPLC-DAD-APCI-MS n . Altogether 69 carotenoids were detected in red Physalis, thereof, 45 were identified. In yellow Physalis, 40 carotenoids were detected and 33 were identified. Zeaxanthin esters with various fatty acids were found to be the most abundant carotenoids in red Physalis, accounting for 51-63% of total carotenoids, followed by β-cryptoxanthin esters (16-24%). In yellow Physalis, mainly free carotenoids such as lutein and β-carotene were found. Total carotenoid contents ranged between 19.8 and 21.6 mg/100 g fresh red Physalis fruits and 1.28-1.38 mg/100 g fresh yellow Physalis fruits, demonstrating that Physalis fruits are rich sources of dietary carotenoids. Yellow Physalis calyces contained only 153-306 μg carotenoids/g dry weight, while those of red Physalis contained substantially higher amounts (14.6-17.6 mg/g dry weight), thus possibly exhibiting great potential as a natural source for commercial zeaxanthin extraction.

Roegneria alashanica Keng: a species with the StStStYStY genome constitution.

Science.gov (United States)

Wang, Richard R-C; Jensen, Kevin B

2017-06-01

The genome constitution of tetraploid Roegneria alashanica Keng has been in question for a long time. Most scientific studies have suggested that R. alashanica had two versions of the St genome, St 1 St 2 , similar to that of Pseudoroegneria elytrigioides (C. Yen & J.L. Yang) B.R. Lu. A study, however, concluded that R. alashanica had the StY genome formula typical for tetraploid species of Roegneria. For the present study, R. alashanica, Elymus longearistatus (Bioss.) Tzvelev (StY genomes), Pseudoroegneria strigosa (M. Bieb.) Á. Löve (St), Pseudoroegneria libanoctica (Hackel) D.R. Dewey (St), and Pseudoroegneria spicata (Pursh) Á. Löve (St) were screened for the Y-genome specific marker B14(F+R) 269 . All E. longearistatus plants expressed intense bands specific to the Y genome. Only 6 of 10 R. alashanica plants exhibited relatively faint bands for the STS marker. Previously, the genome in species of Pseudoroegneria exhibiting such faint Y-genome specific marker was designated as St Y . Based on these results, R. alashanica lacks the Y genome in E. longearistatus but likely possess two remotely related St genomes, St and St Y . According to its genome constitution, R. alashanica should be classified in the genus Pseudoroenera and given the new name Pseudoroegneria alashanica (Keng) R.R.-C. Wang and K.B. Jensen.

Floristic composition and soil fertility in gold mining of Lavrinha, Pontes and Lacerda, MT, Brazil

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Tatiani Botini Pires

2011-12-01

Full Text Available The mining activities cause intense environmental degradation, especially to the soil and vegetation. This study evaluated attributes of floristic composition and soil fertility in areas of open gold mining areas. One hundred plots of 10 × 10 m were distributed in the area effectively mined and in its surroundings. Stem circunference measures (AGC of all identified woody individuals with greater than or equal to 9 cm were taken at 0.3 m height above the ground. In all plots soil samples at 0-20 cm depth were collected for analysis of fertility attributes that are routinely evaluated. In total we observed the occurrence of 92 species and 43 families. The most abundant families were Myrtaceae, Fabaceae and Dilleniaceae; and families that had the greatest numbers of species were Fabaceae (10, Malpighiaceae (7 and Vochysiaceae (5. In the area effectively mined the species with higher importance value index (IVI were Curatella americana (89.1 Cecropia hololeuca (40.9, Roupala montana (12.5 and Pouteria ramiflora (10.2 while in surrounding of the mined area the species with the highest IVI were Myrcia multiflora (25.6, Caryocar brasiliense (15.7, Magonia pubescens (14.8 and Vatareia macrocarpa (14.4. In both areas, the soil had low pH, low availability of P, K+, Ca2+ and Mg2+ and high Al3+ saturation. In spite of the low soil fertility of the studied area, it was able to maintain an overall density of vegetation with AGC > 9 cm of 430 individuals per hectare in the effectively mined area and of 2,220 individuals per hectare in their surroundings.

Comparative analysis of Lacistema pubescens and dexamethasone on topical treatment of skin inflammation in a chronic disease model and side effects.

Science.gov (United States)

da Silva, Josiane M; Conegundes, Jéssica L M; Pinto, Nícolas C C; Mendes, Renata F; Castañon, Maria Christina M N; Scio, Elita

2018-04-01

This study aimed to evaluate the chronic topical anti-inflammatory activity of the pharmaceutical formulation ProHLP containing the hexane fraction of Lacistema pubescens (HLP). It was also investigated the possible cutaneous and systemic adverse effects of HLP and ProHLP in mice when compared to dexamethasone. The chronic topical anti-inflammatory activity was determined by croton oil multiple application-induced mouse ear oedema model. Histopathological analyses of ear tissue samples sensitized with croton oil were performed. Cutaneous atrophy induced by HLP and topical glucocorticoid treatments and excision skin wounds model to evidenced possible adverse reactions were also determined. ProHLP significantly reduced the mice ear oedema and considerably accelerated the wound-healing process. Also, HLP did not lead cutaneous atrophy and preserved the clinical aspect of the thymus, adrenal and spleen, unlike dexamethasone. The results suggested that ProHLP is an efficient and safer pharmaceutical formulation to treat chronic inflammatory diseases. © 2018 Royal Pharmaceutical Society.

Furano diterpenes from Pterodon pubescens Benth with selective in vitro anticancer activity for prostate cell line

International Nuclear Information System (INIS)

Spindola, Humberto M.; Carvalho, Joao E. de; Ruiz, Ana Lucia T.G.; Rodrigues, Rodney A. F.; Denny, Carina; Sousa, Ilza M. de Oliveira; Foglio, Mary Ann; Tamashiro, Jorge Y.

2009-01-01

Activity guided fractionation of Pterodon pubescens Benth. methylene chloride-soluble fraction afforded novel 6α-acetoxi 7β-hydroxy-vouacapan 1 and four known diterpene furans 2, 3, 4, 5. The compounds were evaluated for in vitro cytotoxic activities against human normal cells and tumour cell lines UACC-62 (melanoma), MCF-7 (breast), NCI-H460 (lung, non-small cells), OVCAR-03 (ovarian), PC-3 (prostate), HT-29 (colon), 786-0 (renal), K562 (leukemia) and NCI-ADR/RES (ovarian expressing phenotype multiple drugs resistance). Results were expressed by three concentration dependent parameters GI 50 (concentration that produces 50% growth inhibition), TGI (concentration that produces total growth inhibition or cytostatic effect) and LC 50 (concentration that produces .50% growth, a cytotoxicity parameter). Also, in vitro cytotoxicity was evaluated against 3T3 cell line (mouse embryonic fibroblasts). Antiproliferative properties of compounds 1, 4 and 5 are herein reported for the first time. These compounds showed selectivity in a concentration-dependent way against human PC-3. Compound 1 demonstrated selectivity 26 fold more potent than the positive control, doxorubicin, for PC-3 (prostrate) cell line based on GI 50 values, causing cytostatic effect (TGI value) at a concentration fifteen times less than positive control. Moreover comparison of 50% lethal concentration (LC 50 value) with positive control (doxorubicin) suggested that compound 1 was less toxic. (author)

Production of Trametes pubescens Laccase under Submerged and Semi-Solid Culture Conditions on Agro-Industrial Wastes

Science.gov (United States)

Rodriguez, Alexander; Osma, Johann F.; Alméciga-Díaz, Carlos J.; Sánchez, Oscar F.

2013-01-01

Laccases are copper-containing enzymes involved in the degradation of lignocellulosic materials and used in the treatment of phenol-containing wastewater. In this study we investigated the effect of culture conditions, i.e. submerged or semi-solid, and copper supplementation on laccase production by Trametes pubescens grown on coffee husk, soybean pod husk, or cedar sawdust. The highest specific laccase activity was achieved when the culture was conducted under submerged conditions supplemented with copper (5 mM), and using coffee husk as substrate. The crude extracts presented two laccase isoforms with molecular mass of 120 (Lac1) and 60 kDa (Lac2). Regardless of the substrate, enzymatic crude extract and purified fractions behaved similarly at different temperatures and pHs, most of them presented the maximum activity at 55 °C and a pH range between 2 and 3. In addition, they showed similar stability and electro-chemical properties. At optimal culture conditions laccase activity was 7.69±0.28 U mg-1 of protein for the crude extract, and 0.08±0.001 and 2.86±0.05 U mg-1 of protein for Lac1 and Lac2, respectively. In summary, these results show the potential of coffee husk as an important and economical growth medium to produce laccase, offering a new alternative use for this common agro-industrial byproduct. PMID:24019936

Impact of human-associated Escherichia coli clonal groups in Antarctic pinnipeds: presence of ST73, ST95, ST141 and ST131.

Science.gov (United States)

Mora, Azucena; García-Peña, Francisco Javier; Alonso, María Pilar; Pedraza-Diaz, Susana; Ortega-Mora, Luis Miguel; Garcia-Parraga, Daniel; López, Cecilia; Viso, Susana; Dahbi, Ghizlane; Marzoa, Juan; Sergeant, Martin J; García, Vanesa; Blanco, Jorge

2018-03-16

There is growing concern about the spreading of human microorganisms in relatively untouched ecosystems such as the Antarctic region. For this reason, three pinniped species (Leptonychotes weddellii, Mirounga leonina and Arctocephalus gazella) from the west coast of the Antartic Peninsula were analysed for the presence of Escherichia spp. with the recovery of 158 E. coli and three E. albertii isolates. From those, 23 harboured different eae variants (α1, β1, β2, ε1, θ1, κ, ο), including a bfpA-positive isolate (O49:H10-A-ST206, eae-k) classified as typical enteropathogenic E. coli. Noteworthy, 62 of the 158 E. coli isolates (39.2%) exhibited the ExPEC status and 27 (17.1%) belonged to sequence types (ST) frequently occurring among urinary/bacteremia ExPEC clones: ST12, ST73, ST95, ST131 and ST141. We found similarities >85% within the PFGE-macrorrestriction profiles of pinniped and human clinic O2:H6-B2-ST141 and O16:H5/O25b:H4-B2-ST131 isolates. The in silico analysis of ST131 Cplx genomes from the three pinnipeds (five O25:H4-ST131/PST43-fimH22-virotype D; one O16:H5-ST131/PST506-fimH41; one O25:H4-ST6252/PST9-fimH22-virotype D1) identified IncF and IncI1 plasmids and revealed high core-genome similarities between pinniped and human isolates (H22 and H41 subclones). This is the first study to demonstrate the worrisome presence of human-associated E. coli clonal groups, including ST131, in Antarctic pinnipeds.

Surveys in 1961 on St. Thomas & St. Croix

DEFF Research Database (Denmark)

Dahl, Thorkel; Licht, Kjeld de Fine

Registration of towns and buildings erected during the Danish reign of the Caribbean Isles of St. Thomas, St. Jan and St. Croix 1671-1917 (now belonging to the USA under the name of Virgin Islands)....

Three members of Medicago truncatula ST family are ubiquitous during development and modulated by nutritional status (MtST1) and dehydration (MtST2 and MtST3).

Science.gov (United States)

Albornos, Lucía; Martín, Ignacio; Labrador, Emilia; Dopico, Berta

2017-07-10

ShooT specific/Specific Tissue (ST) belong to a protein family of unknown function characterized by the DUF2775 domain and produced in specific taxonomic plant families, mainly Fabaceae and Asteraceae, with the Medicago truncatula ST family being the largest. The putative roles proposed for this family are cell elongation, biotic interactions, abiotic stress and N reserve. The aim of this work was to go deeper into the role of three M. truncatula ST proteins, namely ST1, ST2 and ST3. Our starting hypothesis was that each member of the family could perform a specific role, and hence, each ST gene would be subjected to a different type of regulation. The search for cis-acting regulatory elements (CREs) in silico in pST1, pST2 and pST3 promoters showed prevalence of tissue/organ specific motifs, especially root- and seed-specific ones. Light, hormone, biotic and abiotic related motifs were also present. None of these pSTs showed the same combination of CREs, or presented the same activity pattern. In general, pST activity was associated with the vascular cylinder, mainly in roots. Promoter activation was highly specific and dissimilar during reproductive development. The ST1, ST2 and ST3 transcripts accumulated in most of the organs and developmental stages analysed - decreasing with age - and expression was higher in the roots than in the aerial parts and more abundant in light-grown plants. The effect of the different treatments on transcript accumulation indicated that ST1 behaved differently from ST2 and ST3, mainly in response to several hormones and dehydration treatments (NaCl or mannitol), upon which ST1 transcript levels decreased and ST2 and ST3 levels increased. Finally, the ST1 protein was located in the cell wall whereas ST2 and ST3 were present both in the cytoplasm and in the cell wall. The ST proteins studied are ubiquitous proteins that could perform distinct/complementary roles in plant biology as they are encoded by differentially regulated genes

Effect of leaf extract buasbuas (Premna pubescens Blume) for against of bacteria growth Staphylococcus aureus and Salmonella sp in vitro

Science.gov (United States)

Restuati, Martina; Pratiwi, Nanda; Widiyastuti, Gita

2017-08-01

Buasbuas (Premna pubescens Blume) is the one of the medicinal plants in Indonesia. This plant contains flavonoids potential as an antibacterial. Staphylococcus aureus and Salmonella sp is the one of the bacteria that can cause poisoning. This research aims to find out of inhibitory the extract of buasbuas leaves the growth of Staphylococcus aureus and Salmonella sp. This research was conducted in Medan Health Laboratory used hole sinks methods. Buasbuas leaves which has been condensed ethanol extract was diluted using aquadest with a concentration of 0%, 50%, 60%, 70%, 80%, 90% and dropped into MSA (Mannitol Salt Agar) media inoculated bacteria and wich is a hole sinks. Them incubated for 1 × 24 hours at a temperature of 37°C. The results of this research that the buasbuas extract with the different concentrations can inhibit the growth of Staphylococcus aureus, then the result were analyzed used of Non Factorial Experimental Method (ANOVA) where Fcount (337.54)> Ftable 0,05 (2,77); Ftabel 0.01 (4.25). While the maximum concentration buasbuas extract were more effective the growh of bacteria is 90% with average inhibition zone diameter of 11 mm.

ACTIVIDAD FITOTÓXICA DE LOS EXTRACTOS DE CHILE MANZANO (Capsicum pubescens R & P

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Ma. del Rosario García-Mateos

2013-01-01

Full Text Available La búsqueda de nuevos herbicidas de origen natural se ha realizado mediante los estudios de sustancias fitotóxicas debido a que no afectan el ambiente y son menos tóxicos que los sintéticos. En la literatura existen pocas evidencias de los efectos fitotóxicos de los capsaicinoides presentes en el género Capsicum , por lo que el objetivo de la presente investigación fue evaluar in vitro el efecto fitotóxico de los extractos del fruto de chile manzano ( Capsicum pubescens R & P en la germinación y vigor de Amaranthus hybridus L., Lactuca sativa L., Ipomoea purpurea L. y Bidens odorata Cav. Se realizó una prueba de germinación de acuerdo con la metodología de la International Seed Testing Asociation. El efecto de seis concentraciones de extractos (0.5, 1.5, 2.5, 5.0, 10, 20 % v/v, capsaicina (0.1 p/v y ABA (0.01 p/v fue evaluado en un experimento, usando un diseño completamente al azar con cuatro repeticiones de 50 semillas cada una. El testigo fue agua destilada. Las variables evaluadas fueron el número de semillas germinadas (NSG y el vigor (longitud de radícula, LR; longitud de la parte aérea, LPA. Se realizaron análisis de varianza y comparaciones de medias de Tukey ( P ≤ 0.05. El extracto de diclorometano, comparado con el extracto etéreo, causó el mayor efecto fitotóxico sobre la germinación de A. hybridus y L. sativa , en las que el porcentaje se redujo hasta 100 %. También afectó en forma negativa el vigor de I. purpurea . El efecto fitotóxico de la capsaicina sobre la germinación y vigor sólo se manifestó en A. hybridus.

Peter St. John | NREL

Science.gov (United States)

St. John Photo of Peter St. John Peter St. John Researcher III-Chemical Engineering Peter.StJohn @nrel.gov | 303-384-7969 Orcid ID http://orcid.org/0000-0002-7928-3722 Education Peter St. John received his engineering from the University of California at Santa Barbara in 2015. During his Ph.D., St. John applied

Deshidratación osmótica de la papaya chilena (Vasconcellea pubescens) e influencia de la temperatura y concentración de la solución sobre la cinética de transferencia de materia

OpenAIRE

Vega-Gálvez,Antonio; Palacios,Marlene; Boglio,Francisca; Pássaro,Catarina; Jeréz,Catalina; Lemus-Mondaca,Roberto

2007-01-01

El objetivo de este trabajo fue estudiar la cinética de deshidratación osmótica de la papaya chilena (Vasconcellea pubescens), utilizando dos variables experimentales: la temperatura (30, 40, 50 °C) y concentración (40, 50 y 60%) de la solución osmótica. Se determinó la variación de masa total, masa de agua y masa de sólidos solubles y se modeló con las ecuaciones difusionales, además en esta investigación se consideró y utilizó una modificación de la ecuación propuesta por Biswal-Bozorgmehr....

Carbon stock quantification of Morella pubescens (H. & B. ex Willd. Wilbur in two agroecosystems (Nariño, Colombia

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Iván Andrés Delgado Vargas

2016-07-01

Full Text Available The carbon stored in radical biomass of Morella pubescens (Humb. & Bonpl. ex Willd. Wilbur, was quantified, in San Pablo, Nariño, Colombia, with height of 2010 m, average annual rainfall of 1300 mm and average temperature of 17ºC. Three experimental unites: silvopastoral system pasture alley cropping (Ac in two planting distances 4x3m and 4x4m, and natural regeneration system (Rn, 7 individual ware taken by experimental unite with (diameters 5 – 7 cm, by experimental unit, the sample was taken to 70 cm and 140 cm from the tree and three depths (0-15, 15-30, and 30-45 cm. In total 24 simples/trees were taken in 21 selected individuals. The mayor quantity of radical biomass and C stock was presented in the Ac arrangement 4x3 m of 27.6 t.ha-1 (14.1 t.C.ha-1; 24 4 t.ha-1 (12.1 t.C.ha-1 distance 4x4 m and 7.5 t.ha-1 and 2.9 t.ha-1In natural regeneration. In system Ac distance 4x4 m there were not differences in C stored by tree Rn, there was a decrease by 4x3 m, thus, the differences of accumulation between the systems, can obey to the density of the sowing.

Carbon stock of Moso bamboo (Phyllostachys pubescens) forests along a latitude gradient in the subtropical region of China.

Science.gov (United States)

Xu, Mengjie; Ji, Haibao; Zhuang, Shunyao

2018-01-01

Latitude is an important factor that influences the carbon stock of Moso bamboo (Phyllostachys pubescens) forests. Accurate estimation of the carbon stock of Moso bamboo forest can contribute to sufficient evaluation of forests in carbon sequestration worldwide. Nevertheless, the effect of latitude on the carbon stock of Moso bamboo remains unclear. In this study, a field survey with 36 plots of Moso bamboo forests along a latitude gradient was conducted to investigate carbon stock. Results showed that the diameter at breast height (DBH) of Moso bamboo culms increased from 8.37 cm to 10.12 cm that well fitted by Weibull model, whereas the bamboo culm density decreased from 4722 culm ha-1 to 3400 culm ha-1 with increasing latitude. The bamboo biomass carbon decreased from 60.58 Mg C ha-1 to 48.31 Mg C ha-1 from north to south. The total carbon stock of Moso bamboo forests, which comprises soil and biomass carbon, ranged from 87.83 Mg C ha-1 to 119.5 Mg C ha-1 and linearly increased with latitude. As a fast-growing plant, Moso bamboo could be harvested amounts of 6.0 Mg C ha-1 to 7.6 Mg C ha-1 annually, which indicates a high potential of this species for carbon sequestration. Parameters obtained in this study can be used to accurately estimate the carbon stock of Moso bamboo forest to establish models of the global carbon balance.

Desarrollo de un Protocolo de propagación in vitro de Geranium chilloense Wild. ex Kuth. Y Lupinus pubescens Benth. Para la obtención de plantas completas, para la primera etapa de restauración de las quebradas de Quito

OpenAIRE

Benavides Silva, Thaly Gabriela; Córdova Muñoz, Adriana Isabel

2015-01-01

Geranium chilloense Willd. ex Kunth known as geranio de los Chillos, is an ornamental plant, native of Los Andes it can be found in a wild way in the ravines of the Metropolitan District of Quito and it is part of the history of the native flora of Quito since has been described from the Alexander Humboldt and Aimé Bonpland expedition in 1802. Lupinus pubescens Benth, also known as Ashpa chocho or Allpa chocho, is an herbaceous, native and ornamental plant due to the beauty of his flowers, de...

Living and Dead Aboveground Biomass in Mediterranean Forests: Evidence of Old-Growth Traits in a Quercus pubescens Willd. s.l. Stand

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Emilio Badalamenti

2017-05-01

Full Text Available For a long time, human impact has deeply simplified most of the forest ecosystems of the Mediterranean Basin. Here, forests have seldom had the chance to naturally develop a complex and multilayered structure, to host large and old trees and rich biological communities, approaching old-growth conditions. Also for this reason, limited information is currently available about Mediterranean old-growth forests, particularly with regard to deadwood. The main aim of this work is to help fill this critical knowledge gap. In Sicily (Italy, we identified a Quercus pubescens forest that seemed to show some typical old-growth features. Total living volume (360 m3 ha−1 and basal area (34 m2 ha−1 were, respectively, about 6 and 3 times higher than the averages recorded in the regional forest inventory for this forest type. Deadwood was particularly abundant, exceeding the threshold of 30 m3 ha−1, mainly represented by lying dead elements. Dead to live wood ratio reached 9%, a value close to the threshold of 10% considered for Mediterranean old-growth forests. As the investigated forest showed some typical old-growth traits, it deserves to be fully protected and could be a permanent monitoring area for studying deadwood and stand dynamics in mature Mediterranean stands.

Stāstu stāstīšanas izmantošana lasīšanas veicināšanas pasākumos

OpenAIRE

Mežjāne, Signe

2014-01-01

Bakalaura darba mērķis ir noskaidrot, vai stāstu stāstīšana ir efektīvs lasīšanas veicināšanas paņēmiens bērniem. Pētījuma problēma ir mūsdienu bērnu nevēlēšanās lasīt, lasīšanu varētu veicināt stāstu stāstīšana bibliotēkās. Darbā tiek analizēts stāstu stāstīšanas process atbilstoši bērnu vecumposmam, izmantojot dažādus runas stilus. Teorētiskā bāze ir balstīta uz Lasītāja reakcijas kritikas teoriju un Runas darbības teoriju. Galvenie pētījuma uzdevumi ir noskaidrot, vai Latvijas bibliotē...

Metabolomics Analysis of Health Functions of Physalis Pubescens L. using by Ultra-performance Liquid Chromatography/Electrospray Ionization Quadruple Time-of-Flight Mass Spectrometry

Institute of Scientific and Technical Information of China (English)

Hang Chu; Hui Sun; Guang-Li Yan; Ai-Hua Zhang; Chang Liu; Hui Dong; Xiang-Cai Meng; Xi-Jun Wang

2015-01-01

Herbal medicines may benefit from metabolomics studies, and applying metabolomics may provide answers about which herbal interventions may be effective for individuals, which metabolic processes are triggered, and the subsequent chemical pathways of activity. Physalis pubescens L (PPL) is an herbal fruit for one year living plant and has been developed into healthy function’s food. However, the mechanisms of health functions are still unclear. To comprehensively and holistically assess its anti-fatigue and antioxidant effects, a novel integrative metabolomics approach was applied. In this study, we present metabolomics analysis applying ultra performance liquid chromatography coupled to quadrupole with time-of-flight mass spectrometry (UPLC-Q/TOF-MS) to determine metabolite alterations after oral administration PPL to rats. Fifteen metabolites in urine were identified as potential biomarkers. Pattern analysis of the UPLC-Q/TOF-MS data disclosed that PPL could relieve fatigue rats by ameliorating the disturbance in amino acids metabolism and energy metabolism, alleviating the oxidative stress from reactive oxygen species and the inflammatory damage, and recovering the destructed regulation. Based on these results, we demonstrated that PPL is a promising source of natural anti-fatigue and antioxidants material for use in functional foods and medicines.

75 FR 51945 - Safety Zone; Potomac River, St. Mary's River, St. Inigoes, MD

Science.gov (United States)

2010-08-24

...-AA00 Safety Zone; Potomac River, St. Mary's River, St. Inigoes, MD AGENCY: Coast Guard, DHS. ACTION... of the St. Mary's River, a tributary of the Potomac River. This action is necessary to provide for.... Navy helicopter located near St. Inigoes, Maryland. This safety zone is intended to protect the...

Organic acid compounds in root exudation of Moso Bamboo (Phyllostachys pubescens) and its bioactivity as affected by heavy metals.

Science.gov (United States)

Chen, Junren; Shafi, Mohammad; Wang, Ying; Wu, Jiasen; Ye, Zhengqian; Liu, Chen; Zhong, Bin; Guo, Hua; He, Lizhi; Liu, Dan

2016-10-01

Moso bamboo (Phyllostachys pubescens) has great potential as phytoremediation material in soil contaminated by heavy metals. A hydroponics experiment was conducted to determine organic acid compounds of root exudates of lead- (Pb), zinc- (Zn), copper- (Cu), and cadmium (Cd)-tolerant of Moso bamboo. Plants were grown in nutrients solution which included Pb, Zn, Cu, and Cd applied as Pb(NO 3 ) 2 (200 μM), ZnSO 4 ·7H 2 O (100 μM), CuSO 4 ·5H 2 O (25 μM), and CdCl 2 (10 μM), respectively. Oxalic acid and malic acid were detected in all treatments. Lactic acid was observed in Cu, Cd, and control treatments. The oxalic was the main organic acid exudated by Moso bamboo. In the sand culture experiment, the Moso bamboo significantly activated carbonate heavy metals under activation of roots. The concentration of water-soluble metals (except Pb) in sand were significantly increased as compared with control. Organic acids (1 mM mixed) were used due to its effect on the soil adsorption of heavy metals. After adding mixed organic acids, the Cu and Zn sorption capacity in soils was decreased markedly compared with enhanced Pb and Cd sorption capacity in soils. The sorption was analyzed using Langmuir and Freundlich equations with R 2 values that ranged from 0.956 to 0.999 and 0.919 to 0.997, respectively.

Recent invasion of the mountain birch Betula pubescens ssp. tortuosa above the treeline due to climate change: genetic and ecological study in northern Sweden.

Science.gov (United States)

Truong, C; Palmé, A E; Felber, F

2007-01-01

Mountain birch, Betula pubescens ssp. tortuosa, forms the treeline in northern Sweden. A recent shift in the range of the species associated with an elevation of the treeline is commonly attributed to climate warming. Using microsatellite markers, we explored the genetic structure of populations along an altitudinal gradient close to the treeline. Low genetic differentiation was found between populations, whereas high genetic diversity was maintained within populations. High level of gene flow compensated for possible losses of genetic diversity at higher elevations and dissipated the founding effect of newly established populations above the treeline. Spatial autocorrelation analysis showed low spatial genetic structure within populations because of extensive gene flow. At the treeline, significant genetic structure within the juvenile age class at small distances did not persist in the adult age class, indicating recent expansion of young recruits due to the warming of the climate. Finally, seedling performance above the treeline was positively correlated with parameters related to temperature. These data confirm the high migration potential of the species in response to fluctuating environmental conditions and indicate that it is now invading higher altitudes due to the recent warming of the climate.

Effect of epimedium pubescen flavonoid on bone mineral status and bone turnover in male rats chronically exposed to cigarette smoke.

Science.gov (United States)

Gao, Shu-guang; Cheng, Ling; Li, Kang-hua; Liu, Wen-He; Xu, Mai; Jiang, Wei; Wei, Li-Cheng; Zhang, Fang-jie; Xiao, Wen-feng; Xiong, Yi-lin; Tian, Jian; Zeng, Chao; Sun, Jin-peng; Xie, Qiang; Lei, Guang-hua

2012-06-19

Epimedii herba is one of the most frequently used herbs in formulas that are prescribed for the treatment of osteoporosis in China and its main constituent is Epimedium pubescen flavonoid (EPF). However, it is unclear whether EPF during chronic exposure to cigarette smoke may have a protective influence on the skeleton. The present study investigated the effect of EPF on bone mineral status and bone turnover in a rat model of human relatively high exposure to cigarette smoke. Fifty male Wistar rats were randomized into five groups: controls, passive smoking groups and passive smoking rats administered EPF at three dosage levels (75, 150 or 300 mg/kg/day) in drinking water for 4 months. A rat model of passive smoking was prepared by breeding male rats in a cigarette-smoking box. Bone mineral content (BMC), bone mineral density (BMD), bone turnover markers, bone histomorphometric parameters and biomechanical properties were examined. Smoke exposure decreased BMC and BMD, increased bone turnover (inhibited bone formation and stimulated its resorption), affected bone histomorphometry (increased trabecular separation and osteoclast surface per bone surface; decreased trabecular bone volume, trabecular thickness, trabecular number, cortical thickness, bone formation rate and osteoblast surface per bone surface), and reduced mechanical properties. EPF supplementation during cigarette smoke exposure prevented smoke-induced changes in bone mineral status and bone turnover. The results suggest that EPF can prevent the adverse effects of smoke exposure on bone by stimulating bone formation and inhibiting bone turnover and bone resorption.

78 FR 19632 - Special Local Regulations; St. Thomas Carnival Watersport Activities, Charlotte Amalie Harbor; St...

Science.gov (United States)

2013-04-02

...-AA08 Special Local Regulations; St. Thomas Carnival Watersport Activities, Charlotte Amalie Harbor; St... proposes to establish a special local regulation on the waters of Charlotte Amalie Harbor in St Thomas, USVI during the St. Thomas Carnival Watersport Activities, a high speed boat race. The event is...

ACRR fission product release tests: ST-1 and ST-2

International Nuclear Information System (INIS)

Allen, M.D.; Stockman, H.W.; Reil, K.O.; Grimley, A.J.; Camp, W.J.

1988-01-01

Two experiments (ST-1 and ST-2) have been performed in the Annular Core Research Reactor (ACRR) at Sandia National Laboratories (SNLA) to obtain time-resolved data on the release of fission products from irradiated fuels under light water reactor (LWR) severe accident conditions. Both experiments were conducted in a highly reducing environment at maximum fuel temperatures of greater than 2400 K. These experiments were designed specifically to investigate the effect of increased total pressure on fission product release; ST-1 was performed at approximately 0.16 MPa and ST-2 was run at 1.9 MPa, whereas other parameters were matched as closely as possible. Release rate data were measured for Cs, I, Ba, Sr, Eu, Te, and U. The release rates were higher than predicted by existing codes for Ba, Sr, Eu, and U. Te release was very low, but Te did not appear to be sequestered by the zircaloy cladding; it was evenly distributed in the fuel. In addition, in posttest analysis a unique fuel morphology (fuel swelling) was observed which may have enhanced fission product release, especially in the high pressure test (ST-2). These data are compared with analytical results from the CORSOR correlation and the VICTORIA computer model

Desidratação osmótica do mamão chileno (Vasconcellea pubescens) e influência da temperatura e concentração da solução sobre a cinética de transferência de matéria

OpenAIRE

Vega-Gálvez, Antonio; Palacios, Marlene; Boglio, Francisca; Pássaro, Catarina; Jeréz, Catalina; Lemus-Mondaca, Roberto

2007-01-01

El objetivo de este trabajo fue estudiar la cinética de deshidratación osmótica de la papaya chilena (Vasconcellea pubescens), utilizando dos variables experimentales: la temperatura (30, 40, 50 °C) y concentración (40, 50 y 60%) de la solución osmótica. Se determinó la variación de masa total, masa de agua y masa de sólidos solubles y se modeló con las ecuaciones difusionales, además en esta investigación se consideró y utilizó una modificación de la ecuación propuesta por Biswal-Bozorgmehr....

Galleria mellonella infection model demonstrates high lethality of ST69 and ST127 uropathogenic E. coli.

Directory of Open Access Journals (Sweden)

Majed F Alghoribi

Full Text Available Galleria mellonella larvae are an alternative in vivo model for investigating bacterial pathogenicity. Here, we examined the pathogenicity of 71 isolates from five leading uropathogenic E. coli (UPEC lineages using G. mellonella larvae. Larvae were challenged with a range of inoculum doses to determine the 50% lethal dose (LD50 and for analysis of survival outcome using Kaplan-Meier plots. Virulence was correlated with carriage of a panel of 29 virulence factors (VF. Larvae inoculated with ST69 and ST127 isolates (10(4 colony-forming units/larvae showed significantly higher mortality rates than those infected with ST73, ST95 and ST131 isolates, killing 50% of the larvae within 24 hours. Interestingly, ST131 isolates were the least virulent. We observed that ST127 isolates are significantly associated with a higher VF-score than isolates of all other STs tested (P≤0.0001, including ST69 (P<0.02, but one ST127 isolate (strain EC18 was avirulent. Comparative genomic analyses with virulent ST127 strains revealed an IS1 mediated deletion in the O-antigen cluster in strain EC18, which is likely to explain the lack of virulence in the larvae infection model. Virulence in the larvae was not correlated with serotype or phylogenetic group. This study illustrates that G. mellonella are an excellent tool for investigation of the virulence of UPEC strains. The findings also support our suggestion that the incidence of ST127 strains should be monitored, as these isolates have not yet been widely reported, but they clearly have a pathogenic potential greater than that of more widely recognised clones, including ST73, ST95 or ST131.

Epidemic potential of Escherichia coli ST131 and Klebsiella pneumoniae ST258: a systematic review and meta-analysis

Science.gov (United States)

Dautzenberg, M J D; Haverkate, M R; Bonten, M J M; Bootsma, M C J

2016-01-01

Objectives Observational studies have suggested that Escherichia coli sequence type (ST) 131 and Klebsiella pneumoniae ST258 have hyperendemic properties. This would be obvious from continuously high incidence and/or prevalence of carriage or infection with these bacteria in specific patient populations. Hyperendemicity could result from increased transmissibility, longer duration of infectiousness, and/or higher pathogenic potential as compared with other lineages of the same species. The aim of our research is to quantitatively estimate these critical parameters for E. coli ST131 and K. pneumoniae ST258, in order to investigate whether E. coli ST131 and K. pneumoniae ST258 are truly hyperendemic clones. Primary outcome measures A systematic literature search was performed to assess the evidence of transmissibility, duration of infectiousness, and pathogenicity for E. coli ST131 and K. pneumoniae ST258. Meta-regression was performed to quantify these characteristics. Results The systematic literature search yielded 639 articles, of which 19 data sources provided information on transmissibility (E. coli ST131 n=9; K. pneumoniae ST258 n=10)), 2 on duration of infectiousness (E. coli ST131 n=2), and 324 on pathogenicity (E. coli ST131 n=285; K. pneumoniae ST258 n=39). Available data on duration of carriage and on transmissibility were insufficient for quantitative assessment. In multivariable meta-regression E. coli isolates causing infection were associated with ST131, compared to isolates only causing colonisation, suggesting that E. coli ST131 can be considered more pathogenic than non-ST131 isolates. Date of isolation, location and resistance mechanism also influenced the prevalence of ST131. E. coli ST131 was 3.2 (95% CI 2.0 to 5.0) times more pathogenic than non-ST131. For K. pneumoniae ST258 there were not enough data for meta-regression assessing the influence of colonisation versus infection on ST258 prevalence. Conclusions With the currently available data

33 CFR 100.915 - St. Clair River Classic Offshore Race, St. Clair, MI.

Science.gov (United States)

2010-07-01

... 33 Navigation and Navigable Waters 1 2010-07-01 2010-07-01 false St. Clair River Classic Offshore Race, St. Clair, MI. 100.915 Section 100.915 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY REGATTAS AND MARINE PARADES SAFETY OF LIFE ON NAVIGABLE WATERS § 100.915 St. Clair River...

St2-80: a new FISH marker for St genome and genome analysis in Triticeae.

Science.gov (United States)

Wang, Long; Shi, Qinghua; Su, Handong; Wang, Yi; Sha, Lina; Fan, Xing; Kang, Houyang; Zhang, Haiqin; Zhou, Yonghong

2017-07-01

The St genome is one of the most fundamental genomes in Triticeae. Repetitive sequences are widely used to distinguish different genomes or species. The primary objectives of this study were to (i) screen a new sequence that could easily distinguish the chromosome of the St genome from those of other genomes by fluorescence in situ hybridization (FISH) and (ii) investigate the genome constitution of some species that remain uncertain and controversial. We used degenerated oligonucleotide primer PCR (Dop-PCR), Dot-blot, and FISH to screen for a new marker of the St genome and to test the efficiency of this marker in the detection of the St chromosome at different ploidy levels. Signals produced by a new FISH marker (denoted St 2 -80) were present on the entire arm of chromosomes of the St genome, except in the centromeric region. On the contrary, St 2 -80 signals were present in the terminal region of chromosomes of the E, H, P, and Y genomes. No signal was detected in the A and B genomes, and only weak signals were detected in the terminal region of chromosomes of the D genome. St 2 -80 signals were obvious and stable in chromosomes of different genomes, whether diploid or polyploid. Therefore, St 2 -80 is a potential and useful FISH marker that can be used to distinguish the St genome from those of other genomes in Triticeae.

76 FR 44531 - Safety Zone; Fourth Annual Chillounge Night St. Petersburg Fireworks Display, Tampa Bay, St...

Science.gov (United States)

2011-07-26

...-AA00 Safety Zone; Fourth Annual Chillounge Night St. Petersburg Fireworks Display, Tampa Bay, St... proposes to establish a temporary safety zone on the waters of Tampa Bay in St. Petersburg, Florida during the Fourth Annual Chillounge Night St. Petersburg Fireworks Display on Saturday, November 19, 2011...

76 FR 68098 - Safety Zone; Fourth Annual Chillounge Night St. Petersburg Fireworks Display, Tampa Bay, St...

Science.gov (United States)

2011-11-03

...-AA00 Safety Zone; Fourth Annual Chillounge Night St. Petersburg Fireworks Display, Tampa Bay, St... Guard is establishing a temporary safety zone on the waters of Tampa Bay in St. Petersburg, Florida during the Fourth Annual Chillounge Night St. Petersburg Fireworks Display on Saturday, November 19, 2011...

ST peak during percutaneous coronary intervention serves as an early prognostic predictor in patients with ST-segment elevation myocardial

DEFF Research Database (Denmark)

Lønborg, Jacob; Kelbæk, Henning; Engstrøm, Thomas

2014-01-01

AIMS: To evaluate the clinical importance of the ST peak phenomenon during primary percutaneous coronary intervention (PCI) in patients with ST-segment elevation myocardial infarction (STEMI). METHODS AND RESULTS: Continuous ST monitoring was performed in 942 STEMI patients from arrival until 90...... minutes after revascularisation. ST peak was defined as ≥1 mm increase in the ST-segment during PCI compared with the ST elevation before intervention. ST peak was observed in 26.9% of patients. During median follow-up of 4.1 years, 20.7% of patients experienced a major adverse cardiac event (MACE). ST...... and ST peak including ST resolution and epicardial flow, ST peak remained significantly associated with MACE: adjusted hazard ratio (HR) 1.40 (95% confidence interval [CI] 1.01-1.95) and 1.41 (95% CI: 1.02-1.96). CONCLUSIONS: In the largest study hitherto evaluating the ST peak phenomenon during primary...

Biosynthesis, Characterization, and Bioactivities Evaluation of Silver and Gold Nanoparticles Mediated by the Roots of Chinese Herbal Angelica pubescens Maxim

Science.gov (United States)

Markus, Josua; Wang, Dandan; Kim, Yeon-Ju; Ahn, Sungeun; Mathiyalagan, Ramya; Wang, Chao; Yang, Deok Chun

2017-01-01

A facile synthesis and biological applications of silver (DH-AgNps) and gold nanoparticles (DH-AuNps) mediated by the aqueous extract of Angelicae Pubescentis Radix (Du Huo) are explored. Du Huo is a medicinal root belonging to Angelica pubescens Maxim which possesses anti-inflammatory, analgesic, and antioxidant properties. The absorption spectra of nanoparticles in varying root extract and metal ion concentration, pH, reaction temperatures, and time were recorded by ultraviolet-visible (UV-Vis) spectroscopy. The presence of DH-AgNps and DH-AuNps was confirmed from the surface plasmon resonance intensified at 414 and 540 nm, respectively. Field emission transmission electron micrograph (FE-TEM) analysis revealed the formation of quasi-spherical DH-AgNps and spherical icosahedral DH-AuNps. These novel DH-AgNps and DH-AuNps maintained an average crystallite size of 12.48 and 7.44 nm, respectively. The biosynthesized DH-AgNps and DH-AuNps exhibited antioxidant activity against 2,2-diphenyl-1-picrylhydrzyl (DPPH) radicals and the former exhibited antimicrobial activity against clinical pathogens including Escherichia coli, Staphylococcus aureus, Pseudomonas aeruginosa, and Salmonella enterica. The expected presence of flavonoids, sesquiterpenes, and phenols on the nanoparticle surface were conjectured to grant protection against aggregation and free radical scavenging activity. DH-AgNps and DH-AuNps were further investigated for their cytotoxic properties in RAW264.7 macrophages for their potential application as drug carriers to sites of inflammation. In conclusion, this green synthesis is favorable for the advancement of plant mediated nano-carriers in drug delivery systems, cancer diagnostic, and medical imaging.

Effect of epimedium pubescen flavonoid on bone mineral status and bone turnover in male rats chronically exposed to cigarette smoke

Directory of Open Access Journals (Sweden)

Gao Shu-guang

2012-06-01

Full Text Available Abstract Background Epimedii herba is one of the most frequently used herbs in formulas that are prescribed for the treatment of osteoporosis in China and its main constituent is Epimedium pubescen flavonoid (EPF. However, it is unclear whether EPF during chronic exposure to cigarette smoke may have a protective influence on the skeleton. The present study investigated the effect of EPF on bone mineral status and bone turnover in a rat model of human relatively high exposure to cigarette smoke. Methods Fifty male Wistar rats were randomized into five groups: controls, passive smoking groups and passive smoking rats administered EPF at three dosage levels (75, 150 or 300 mg/kg/day in drinking water for 4 months. A rat model of passive smoking was prepared by breeding male rats in a cigarette-smoking box. Bone mineral content (BMC, bone mineral density (BMD, bone turnover markers, bone histomorphometric parameters and biomechanical properties were examined. Results Smoke exposure decreased BMC and BMD, increased bone turnover (inhibited bone formation and stimulated its resorption, affected bone histomorphometry (increased trabecular separation and osteoclast surface per bone surface; decreased trabecular bone volume, trabecular thickness, trabecular number, cortical thickness, bone formation rate and osteoblast surface per bone surface, and reduced mechanical properties. EPF supplementation during cigarette smoke exposure prevented smoke-induced changes in bone mineral status and bone turnover. Conclusion The results suggest that EPF can prevent the adverse effects of smoke exposure on bone by stimulating bone formation and inhibiting bone turnover and bone resorption.

From 21st century skills to 21st century human being

DEFF Research Database (Denmark)

Hjøllund, Niels-Peder Osmundsen; Jørgensen, Tobias Heiberg

2017-01-01

In Denmark, in Scandinavia and in all of Europe there is a lot of talk about the skills of the future. But if we want our students to aim for and gain a different learning outcome, we must set new and different standards for the way we teach – and start to walk the talk. The focus of the presenta...... CLD and we must take the next step, where we stop thinking about skills and competencies and start thinking and acting on the fundamental existential implication of the 21st century. What we need now is not more 21st century skills, but 21st century human beings....

76 FR 55158 - Approval of Noise Compatibility Program for Lambert-St. Louis International Airport, St. Louis, MO

Science.gov (United States)

2011-09-06

... Program for Lambert-St. Louis International Airport, St. Louis, MO AGENCY: Federal Aviation Administration... noise compatibility program submitted by the St. Louis Airport Authority under the provisions of 49 U.S...''). On April 5, 2011, the FAA determined that the noise exposure maps submitted by the St. Louis Airport...

The spread of KPC-producing Enterobacteriaceae in Spain: WGS analysis of the emerging high-risk clones of Klebsiella pneumoniae ST11/KPC-2, ST101/KPC-2 and ST512/KPC-3.

Science.gov (United States)

Oteo, Jesús; Pérez-Vázquez, María; Bautista, Verónica; Ortega, Adriana; Zamarrón, Pilar; Saez, David; Fernández-Romero, Sara; Lara, Noelia; Ramiro, Raquel; Aracil, Belén; Campos, José

2016-12-01

We analysed the microbiological traits and population structure of KPC-producing Enterobacteriaceae isolates collected in Spain between 2012 and 2014. We also performed a comparative WGS analysis of the three major KPC-producing Klebsiella pneumoniae clones detected. Carbapenemase and ESBL genes were sequenced. The Institut Pasteur MLST scheme was used. WGS data were used to construct phylogenetic trees, to identify the determinants of resistance and to de novo assemble the genome of one representative isolate of each of the three major K. pneumoniae clones. Of the 2443 carbapenemase-producing Enterobacteriaceae isolates identified during the study period, 111 (4.5%) produced KPC. Of these, 81 (73.0%) were K. pneumoniae and 13 (11.7%) were Enterobacter cloacae. Three major epidemic clones of K. pneumoniae were identified: ST11/KPC-2, ST101/KPC-2 and ST512/KPC-3. ST11/KPC-2 differed from ST101/KPC-2 and ST512/KPC-3 by 27 819 and 6924 SNPs, respectively. ST101/KPC-2 differed from ST512/KPC-3 by 28 345 SNPs. Nine acquired resistance genes were found in ST11/KPC-2, 11 in ST512/KPC-3 and 13 in ST101/KPC-2. ST101/KPC-2 had the highest number of virulence genes (20). An 11 bp deletion at the end of the mgrB sequence was the cause of colistin resistance in ST512/KPC-3. KPC-producing Enterobacteriaceae are increasing in Spain. Most KPC-producing K. pneumoniae isolates belonged to only five clones: ST11 and ST512 caused interregional spread, ST101 caused regional spread and ST1961 and ST678 produced independent hospital outbreaks. ST101/KPC-2 had the highest number of resistance and virulence genes. ST101/KPC-2 and ST512/KPC-3 were recently implicated in the spread of KPC in Italy. © The Author 2016. Published by Oxford University Press on behalf of the British Society for Antimicrobial Chemotherapy. All rights reserved. For Permissions, please e-mail: journals.permissions@oup.com.

Team Danmarks støttekoncept

DEFF Research Database (Denmark)

Storm, Rasmus K.

Evaluering af Team Danmarks støttekoncept 2005-2008 med omfattende analyser af Team Danmarks virke, dets støttekoncept og de samarbejdsrelationer med specialforbund, udøvere, politisk valgte ledere, trænere mv., som udmøntningen af støttekonceptet forudsætter. Herunder analyse af...

Ocular Toxicity Profile of ST-162 and ST-168 as Novel Bifunctional MEK/PI3K Inhibitors.

Science.gov (United States)

Smith, Andrew; Pawar, Mercy; Van Dort, Marcian E; Galbán, Stefanie; Welton, Amanda R; Thurber, Greg M; Ross, Brian D; Besirli, Cagri G

2018-04-30

ST-162 and ST-168 are small-molecule bifunctional inhibitors of MEK and PI3K signaling pathways that are being developed as novel antitumor agents. Previous small-molecule and biologic MEK inhibitors demonstrated ocular toxicity events that were dose limiting in clinical studies. We evaluated in vitro and in vivo ocular toxicity profiles of ST-162 and ST-168. Photoreceptor cell line 661W and adult retinal pigment epithelium cell line ARPE-19 were treated with increasing concentrations of bifunctional inhibitors. Western blots, cell viability, and caspase activity assays were performed to evaluate MEK and PI3K inhibition and dose-dependent in vitro toxicity, and compared with monotherapy. In vivo toxicity profile was assessed by intravitreal injection of ST-162 and ST-168 in Dutch-Belted rabbits, followed by ocular examination and histological analysis of enucleated eyes. Retinal cell lines treated with ST-162 or ST-168 exhibited dose-dependent inhibition of MEK and PI3K signaling. Compared with inhibition by monotherapies and their combinations, bifunctional inhibitors demonstrated reduced cell death and caspase activity. In vivo, both bifunctional inhibitors exhibited a more favorable toxicity profile when compared with MEK inhibitor PD0325901. Novel MEK and PI3K bifunctional inhibitors ST-162 and ST-168 demonstrate favorable in vitro and in vivo ocular toxicity profiles, supporting their further development as potential therapeutic agents targeting multiple aggressive tumors.

St. John's Wort (image)

Science.gov (United States)

The herb St. John's Wort is believed to be helpful in relieving mild to moderate depression, but should only be taken under a physician's supervision. St. John's Wort may clash with other medications or ...

ACHP | News | St. Elizabeths Programmatic Agreement Signed

Science.gov (United States)

Search skip specific nav links Home arrow News arrow St. Elizabeths Programmatic Agreement Signed St redevelopment of the St. Elizabeths West Campus, which is part of the St. Elizabeths National Historic Landmark this project, due to the historic significance of the NHL. GSA's client for the St. Elizabeths

First genome report on novel sequence types of Neisseria meningitidis: ST12777 and ST12778.

Science.gov (United States)

Veeraraghavan, Balaji; Lal, Binesh; Devanga Ragupathi, Naveen Kumar; Neeravi, Iyyan Raj; Jeyaraman, Ranjith; Varghese, Rosemol; Paul, Miracle Magdalene; Baskaran, Ashtawarthani; Ranjan, Ranjini

2018-03-01

Neisseria meningitidis is an important causative agent of meningitis and/or sepsis with high morbidity and mortality. Baseline genome data on N. meningitidis, especially from developing countries such as India, are lacking. This study aimed to investigate the whole genome sequences of N. meningitidis isolates from a tertiary care centre in India. Whole-genome sequencing was performed using an Ion Torrent™ Personal Genome Machine™ (PGM) with 400-bp chemistry. Data were assembled de novo using SPAdes Genome Assembler v.5.0.0.0. Sequence annotation was performed through PATRIC, RAST and the NCBI PGAAP server. Downstream analysis of the isolates was performed using the Center for Genomic Epidemiology databases for antimicrobial resistance genes and sequence types. Virulence factors and CRISPR were analysed using the PubMLST database and CRISPRFinder, respectively. This study reports the whole genome shotgun sequences of eight N. meningitidis isolates from bloodstream infections. The genome data revealed two novel sequence types (ST12777 and ST12778), along with ST11, ST437 and ST6928. The virulence profile of the isolates matched their sequence types. All isolates were negative for plasmid-mediated resistance genes. To the best of our knowledge, this is the first report of ST11 and ST437 N. meningitidis isolates in India along with two novel sequence types (ST12777 and ST12778). These results indicate that the sequence types circulating in India are diverse and require continuous monitoring. Further studies strengthening the genome data on N. meningitidis are required to understand the prevalence, spread, exact resistance and virulence mechanisms along with serotypes. Copyright © 2017 International Society for Chemotherapy of Infection and Cancer. Published by Elsevier Ltd. All rights reserved.

78 FR 7663 - SLR; 2013 International Rolex Regatta; St. Thomas Harbor; St. Thomas, U.S. Virgin Islands

Science.gov (United States)

2013-02-04

... 1625-AA08 SLR; 2013 International Rolex Regatta; St. Thomas Harbor; St. Thomas, U.S. Virgin Islands... special local regulations on the waters of St. Thomas Harbor in St. Thomas, U. S. Virgin Islands during... 5 p.m., Monday through Friday, except federal holidays. The telephone number is 202-366-9329. See...

Isolation and characterization of styrene metabolism genes from styrene-assimilating soil bacteria Rhodococcus sp. ST-5 and ST-10.

Science.gov (United States)

Toda, Hiroshi; Itoh, Nobuya

2012-01-01

Styrene metabolism genes were isolated from styrene-assimilating bacteria Rhodococcus sp. ST-5 and ST-10. Strain ST-5 had a gene cluster containing four open reading frames which encoded styrene degradation enzymes. The genes showed high similarity to styABCD of Pseudomonas sp. Y2. On the other hand, strain ST-10 had only two genes which encoded styrene monooxygenase and flavin oxidoreductase (styAB). Escherichia coli transformants possessing the sty genes of strains ST-5 and ST-10 produced (S)-styrene oxide from styrene, indicating that these genes function as styrene degradation enzymes. Metabolite analysis by resting-cell reaction with gas chromatography-mass spectrometry revealed that strain ST-5 converts styrene to phenylacetaldehyde via styrene oxide by styrene oxide isomerase (styC) reaction. On the other hand, strain ST-10 lacked this enzyme, and thus accumulated styrene oxide as an intermediate. HPLC analysis showed that styrene oxide was spontaneously isomerized to phenylacetaldehyde by chemical reaction. The produced phenylacetaldehyde was converted to phenylacetic acid (PAA) in strain ST-10 as well as in strain ST-5. Furthermore, phenylacetic acid was converted to phenylacetyl-CoA by the catalysis of phenylacetate-CoA ligase in strains ST-5 and ST-10. This study proposes possible styrene metabolism pathways in Rhodococcus sp. strains ST-5 and ST-10. Copyright © 2011 The Society for Biotechnology, Japan. Published by Elsevier B.V. All rights reserved.

Identifying 21st Century Capabilities

Science.gov (United States)

Stevens, Robert

2012-01-01

What are the capabilities necessary to meet 21st century challenges? Much of the literature on 21st century skills focuses on skills necessary to meet those challenges associated with future work in a globalised world. The result is a limited characterisation of those capabilities necessary to address 21st century social, health and particularly…

If F(ST) does not measure neutral genetic differentiation, then comparing it with Q(ST) is misleading. Or is it?

Science.gov (United States)

Edelaar, Pim; Björklund, Mats

2011-05-01

The comparison between neutral genetic differentiation (F(ST) ) and quantitative genetic differentiation (Q(ST) ) is commonly used to test for signatures of selection in population divergence. However, there is an ongoing discussion about what F(ST) actually measures, even resulting in some alternative metrics to express neutral genetic differentiation. If there is a problem with F(ST) , this could have repercussions for its comparison with Q(ST) as well. We show that as the mutation rate of the neutral marker increases, F(ST) decreases: a higher within-population heterozygosity (He) yields a lower F(ST) value. However, the same is true for Q(ST) : a higher mutation rate for the underlying QTL also results in a lower Q(ST) estimate. The effect of mutation rate is equivalent in Q(ST) and F(ST) . Hence, the comparison between Q(ST) and F(ST) remains valid, if one uses neutral markers whose mutation rates are not too high compared to those of quantitative traits. Usage of highly variable neutral markers such as hypervariable microsatellites can lead to serious biases and the incorrect inference that divergent selection has acted on populations. Much of the discussion on F(ST) seems to stem from the misunderstanding that it measures the differentiation of populations, whereas it actually measures the fixation of alleles. In their capacity as measures of population differentiation, Hedrick's G'(ST) and Jost's D reach their maximum value of 1 when populations do not share alleles even when there remains variation within populations, which invalidates them for comparisons with Q(ST) . © 2011 Blackwell Publishing Ltd.

Transpiration of montane Pinus sylvestris L. and Quercus pubescens Willd. forest stands measured with sap flow sensors in NE Spain

Directory of Open Access Journals (Sweden)

R. Poyatos

2005-01-01

Full Text Available Stand transpiration was measured during the 2003 and 2004 growing seasons using heat dissipation sap flow sensors in a Scots pine (Pinus sylvestris L. and a pubescent oak (Quercus pubescens Willd. forests located in a montane area of the Eastern Pyrenees (NE Spain. The first aim of the study was to assess the differences in quantitative estimates of transpiration (Ec and the response to evaporative demand of the two stands. Over the studied period of 2003, characterised by a severe drought episode during the summer, the oak stand (Ec was only 110 mm compared to the 239 mm transpired by the Scots pine stand, although the ratio of transpiration to reference evapotranspiration (Ec/ET0 in the oak stand compares well with the expected values predicted for low leaf area index (LAI oak forests in southern Europe. Scots pine showed a strong reduction in (Ec/ET0 as the drought developed, whereas pubescent oak was less affected by soil moisture deficits in the upper soil. As a second objective, and given the contrasting meteorological conditions between 2003 and 2004 summer periods, the interannual variability of transpiration was studied in the Scots pine plot. Rainfall during the summer months (June-September in 2003 was almost 40% less than in the same interval in 2004. Accordingly, transpiration was also reduced about 25% in 2003. Finally, Scots pine data from 2003 and 2004 was used to calibrate a simple transpiration model using ET0 and soil moisture deficit (SMD as input variables, and implicitly including stomatal responses to high vapour pressure deficits (Dd and soil water status.

Catalytic effect of KF-846 on the reforming of the primary intermediates from the co-pyrolysis of pubescens and LDPE

International Nuclear Information System (INIS)

Liu, Wen-wu; Hu, Chang-wei; Tong, Dong-mei; Yang, Yu; Li, Gui-ying; Zhu, Liang-fang; Tang, Jin-Qiang

2014-01-01

Highlights: • Reforming reactions were inhibited by H 2 , decrease of acidity and low temperature. • There was a synergistic effect on producing hydrogen between Ni and Mo. • The lattice oxygen over catalyst employed might transfer into the intermediates. • Co-pyrolysis, low temperature and N 2 could restrain oxygen transfer to some extent. - Abstract: Co-pyrolysis is regarded as an effective approach to upgrade the quality of pyrolysis products. In this work the activity of KF-846 was evaluated by co-pyrolysis of pubescens and low density polyethylene under different experimental conditions including catalytic mode, pyrolytic atmosphere and temperature, etc. The results showed that the fresh KF-846 exerted strong effects of cyclization, aromatization, hydrogen transfer and vapor-catalytic reforming reactions on the primary intermediates from the co-pyrolysis. The hydrogen-rich gases indicated a synergistic effect between Ni and Mo over KF-846 on producing hydrogen. More importantly, the reforming reactions might be inhibited to some extent by H 2 atmosphere, the low temperature and the decrease of acidity over catalyst. Furthermore, it was deduced that the oxygen over the lattice of catalyst or some intermediates might transfer into other intermediates, possibly resulting in more products with high oxygen content, but it was presumed that the low temperature, co-pyrolysis process and N 2 atmosphere could repress the trend to a certain degree. The mass and energy balance of co-pyrolysis were analyzed, and the main reaction pathways were also proposed. The interference in pyrolysis by regulating the catalytic mode, pyrolytic atmosphere and temperature, acidity over catalyst might posses a certain guiding significance for the pyrolytic technology and the design/selection of catalysts employed

Effect of ultrasonic treatment on total phenolic extraction from Lavandula pubescens and its application in palm olein oil industry.

Science.gov (United States)

Rashed, Marwan M A; Tong, Qunyi; Abdelhai, Mandour H; Gasmalla, Mohammed A A; Ndayishimiye, Jean B; Chen, Long; Ren, Fei

2016-03-01

The aims of the current study were to evaluate the best technique for total phenolic extraction from Lavandula pubescens (Lp) and its application in vegetable oil industries as alternatives of synthetic food additives (TBHQ and BHT). To achieve these aims, three techniques of extraction were used: ultrasonic-microwave (40 kHz, 50 W, microwave power 480 W, 5 min), ultrasonic-homogenizer (20 kHz, 150 W, 5 min) and conventional maceration as a control. By using the Folin-Ciocalteu method, the total phenolic contents (TPC) (mg gallic acid equivalent/g dry matter) were found to be 253.87, 216.96 and 203.41 for ultrasonic-microwave extract, ultrasonic-homogenizer extract and maceration extract, respectively. The ultrasonic-microwave extract achieved the higher scavenger effect of DPPH (90.53%) with EC50 (19.54 μg/mL), and higher inhibition of β-carotene/linoleate emulsion deterioration (94.44%) with IC50 (30.62 μg/mL). The activity of the ultrasonic-microwave treatment could prolong the induction period (18.82 h) and oxidative stability index (1.67) of fresh refined, bleached and deodorized palm olein oil (RBDPOo) according to Rancimat assay. There was an important synergist effect between citric acid and Lp extracts in improving the oxidative stability of fresh RBDPOo. The results of this work also showed that the ultrasonic-microwave assisted extract was the most effective against Gram-positive and Gram-negative strains that were assessed in this study. The uses of ultrasonic-microwave could induce the acoustic cavitation and rupture of plant cells, and this facilitates the flow of solvent into the plant cells and enhances the desorption from the matrix of solid samples, and thus would enhance the efficiency of extraction based on cavitation phenomenon. Copyright © 2015 Elsevier B.V. All rights reserved.

St. Thomas and St. John, U.S. Virgin Islands Coastal Digital Elevation Model

Data.gov (United States)

National Oceanic and Atmospheric Administration, Department of Commerce — The 1/3 arc-second St. Thomas and St. John, U.S. Virgin Islands Coastal Digital Elevation Model will be used to support NOAA's tsunami forecast system and for...

Radioimmunoimaging of human colon and gastric cancers xenografts by NCC-ST-439 and NCC-ST-433 monoclonal antibodies

International Nuclear Information System (INIS)

Nakamura, Kayoko; Tsukatani, Yasushi; Nishiguchi, Iku

1987-01-01

Both NCC-ST-439 and NCC-ST-433 are monoclonal antibodies raised against human gastric cancer (St-4) xenografts in nude mice. Imaging and localization experiments were performed by injecting I-125 labeled antibodies into nude mice bearing CO-4 (colon carcinoma) and H-111 (gastric carcinoma). There was uptake of NCC-ST-439 (polymer) into the CO-4, though it was not clearly visualized until 5 days post injection. By injecting NCC-ST-439 (monomer), CO-4 was better seen at day 3, while average accumulation into the tumors decreased compared with NCC-ST-439 (polymer). High radioactivities were observed in the liver and spleen, which was probably due to the immunocomplex with the antigen in the blood. NCC-ST-433 was selectively accumulated into the H-111 with tumor to blood ratio 7.8 at day 7, without significant uptake into the liver and spleen. Significant correlation was also found between the tumor uptake level of NCC-ST-433 and size of tumors. Excellent images of H-111 were obtained 3 days after the injection. NCC-ST-433 holds promise for the radioimmunodetection of gastric cancers. (author)

Draft Genome Sequences of Staphylococcus aureus AMRF1 (ST22) and AMRF2 (ST672), Ocular Methicillin-Resistant Isolates

KAUST Repository

Velusamy, Nithya

2014-03-20

Sequence type 22 (ST22) and ST672 are the two major emerging clones of community-acquired methicillin-resistant Staphylococcus aureus in India. ST672 strains were found to cause severe ocular infections. We report the draft genome sequences of two emerging strains of methicillin-resistant S. aureus, AMRF1 (ST22) and AMRF2 (ST672), isolated from patients with ocular infections.

Draft Genome Sequences of Staphylococcus aureus AMRF1 (ST22) and AMRF2 (ST672), Ocular Methicillin-Resistant Isolates

KAUST Repository

Velusamy, Nithya; Prakash, Logambiga; Neelamegam, Sivakumar; Antony, Aju; Prajna, Lalitha; Mohankumar, Vidyarani; Devarajan, Bharanidharan

2014-01-01

Sequence type 22 (ST22) and ST672 are the two major emerging clones of community-acquired methicillin-resistant Staphylococcus aureus in India. ST672 strains were found to cause severe ocular infections. We report the draft genome sequences of two emerging strains of methicillin-resistant S. aureus, AMRF1 (ST22) and AMRF2 (ST672), isolated from patients with ocular infections.

78 FR 16211 - Safety Zone, Corp. Event Finale UHC, St. Thomas Harbor; St. Thomas, U.S. Virgin Islands

Science.gov (United States)

2013-03-14

... 1625-AA00 Safety Zone, Corp. Event Finale UHC, St. Thomas Harbor; St. Thomas, U.S. Virgin Islands... establish a temporary safety zone on the waters of St. Thomas Harbor in St. Thomas, U.S. Virgin Islands... through Friday, except federal holidays. The telephone number is 202-366-9329. See the ``Public...

78 FR 23489 - Safety Zone; V.I. Carnival Finale, St. Thomas Harbor; St. Thomas, U.S.V.I.

Science.gov (United States)

2013-04-19

... waters of St. Thomas Harbor in St. Thomas, U.S. Virgin Islands during the V.I. Carnival Finale, a... through Friday, except Federal holidays. FOR FURTHER INFORMATION CONTACT: If you have questions on this... event. The event will be held on the waters of St. Thomas Harbor, St. Thomas, U. S. Virgin Islands...

78 FR 22778 - Safety Zone; Corp. Event Finale UHC, St. Thomas Harbor; St. Thomas, U.S.V.I.

Science.gov (United States)

2013-04-17

... waters of St. Thomas Harbor in St. Thomas, U.S. Virgin Islands during the Corp. Event Finale UHC, a.... and 5 p.m., Monday through Friday, except Federal holidays. FOR FURTHER INFORMATION CONTACT: If you..., St. Thomas, U. S. Virgin Islands. The fireworks will be launched from a barge stationed near the St...

Different properties of polysialic acids synthesized by the polysialyltransferases ST8SIA2 and ST8SIA4.

Science.gov (United States)

Mori, Airi; Hane, Masaya; Niimi, Yuki; Kitajima, Ken; Sato, Chihiro

2017-09-01

Polysialic acid (polySia) is mainly found as a modification of neural cell adhesion molecule (NCAM) in whole embryonic brains, as well as restricted areas of adult vertebrate brains, including the hippocampus. PolySia shows not only repulsive effects on NCAM-involved cell-cell interactions due to its bulky and hydrated properties, but also attractive effects on the interaction with neurologically active molecules, which exerts a reservoir function. Two different polysialyltransferases, ST8SIA2 and ST8SIA4, are involved in the synthesis of polySia chains; however, to date, the differences of the properties between polySia chains synthesized by these two enzymes remain unknown. In this study, to clarify this point, we first prepared polySia-NCAMs from HEK293 cells stably expressing ST8SIA4 and ST8SIA2, or ST8SIA2 (SNP-7), a mutant ST8SIA2 derived from a schizophrenia patient. The conventional sensitive chemical and immunological characterizations showed that the quantity and quality (structural features) of polySia are not so much different between ST8SIA4- and ST8SIA2-synthesized ones, apart from those of ST8SIA2 (SNP-7). Then, we assessed the homophilic and heterophilic interactions mediated by polySia-NCAM by adopting a surface plasmon resonance measurement as an in vitro analytical method. Our novel findings are as follows: (i) the ST8SIA2- and ST8SIA4-synthesized polySia-NCAMs exhibited different attractive and repulsive effects than each other; (ii) both polySia- and oligoSia-NCAMs synthesized by ST8SIA2 were able to bind polySia-NCAMs; (iii) the polySia-NCAM synthesized by a ST8SIA2 (SNP-7) showed markedly altered attractive and repulsive properties. Collectively, polySia-NCAM is suggested to simultaneously possess both attractive and repulsive properties that are highly regulated by the two polysialyltransferases. © The Author 2017. Published by Oxford University Press. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

77 FR 59035 - Notice of Intent To Rule on Request To Release Airport Property at the St. George Airport, St...

Science.gov (United States)

2012-09-25

... To Release Airport Property at the St. George Airport, St. George, UT AGENCY: Federal Aviation... rule and invite public comment on the release of land at St. George Airport under the provisions of..., City of St. George, Utah, at the following address: Mr. Gary Esplin, City Manager, City of St. George...

Growth response of seedlings of six Betula pubescens Ehrh. provenances to six ozone exposure regimes

Energy Technology Data Exchange (ETDEWEB)

Mortensen, L.M. [Agricultural Univ. of Norway, Aas (Norway). Dept. of Horticulture and Crop Science

1998-07-01

Seedlings of six provenances of Betula pubescens Ehrh. from different latitudes (59-70 deg N) were grown under six ozone exposure regimes by combining different concentrations and daily exposure periods. The different treatments at increasing O{sub 3} exposure over 40 nmol/mol (AOT40 given in parentheses) were: 19 nmol mol{sup -1}/24 h day{sup -1} (0.1 {mu}mol/mol-h), 42 nmol mol{sup -1}/12 h day{sup -1} (2.5 {mu}mol/mol-h), 44 nmol mol{sup -1}/24 h day{sup -1} (7.1 {mu}mol/mol-h), 76 nmol mol{sup -1}/6 day{sup -1} (9.4 {mu}mol/mol-h), 75 nmol mol{sup -1}/12 h day{sup -1} (17.8 {mu}mol/mol{sup -1}) and 116 nmol mol{sup -1}/6 h day{sup -1} (19.8 {mu}mol/mol{sup -1}) for 40 days at a 24 h day{sup -1} photoperiod in growth chambers placed in a greenhouse. The effect of increasing the O{sub 3} exposure from 19 nmol mol{sup -1}/24 h to 42 nmol mol{sup -1}/12 h was a decrease in root but not shoot dry weight. A further increase in the exposure to 44 nmol mol{sup -1}/24 h also decreased the shoot dry weight. An increase in the O{sub 3} concentration to 75 and 116 nmol mol{sup -1} further decreased shoot and root dry weights. A moderate O{sub 3} exposure (42 nmol mol{sup -1}/12 h) increased the plant height and leaf size, while a further increase in O{sub 3} concentration and exposure time decreased both of these variables. The birch provenances generally had a similar response to the O{sub 3} treatments. The accumulated O{sub 3} exposure over the 0, 10, 20, 30, 40 and 50 nmol mol{sup -1} concentrations (AOT0, AOT10, AOT20, AOT30, AOT40 and AOT50, respectively) was calculated for all O{sub 3} treatments. The shoot and root dry weights were correlated best with AOT40 and AOT30, and were estimated to decrease by 10% at an AOT40 of 7.0 and 5.5 {mu}mol mol{sup -1}-h, respectively. The development of O{sub 3} injury (yellow stipples/chlorosis) was most marked when correlated with AOT40 26 refs, 6 figs, 1 tab

Comportamento fisiológico de sementes osmocondicionadas de Platymiscium pubescens Micheli (tamboril-da-mata

Directory of Open Access Journals (Sweden)

Borges Eduardo Euclydes de Lima e

2002-01-01

Full Text Available O objetivo deste trabalho foi investigar alterações fisiológicas e bioquímicas em sementes osmocondicionadas de tamboril-da-mata (Platymiscium pubescens Micheli. Foram analisados o crescimento do eixo embrionário, a germinação, as alterações na parede celular, a mobilização de carboidratos e proteínas e a atividade de a-galactosidase. Observou-se que o teor de umidade das sementes da testemunha aumentou continuamente até 96 horas de embebição, enquanto as mantidas nas soluções de PEG estabilizaram-se a partir de 48 horas. A germinação ocorreu somente nas sementes mantidas em água, alcançando 30% em 120 horas. As sementes mantidas em solução-0,4 MPa de PEG por 120 horas tiveram 66% de germinação quando transferidas para água, sendo a maior em relação aos demais potenciais. A massa fresca e o comprimento do embrião aumentaram significativamente durante o período de 120 horas em solução de PEG (-0,4 MPa/120 horas, porém a massa seca teve incremento não-significativo. Os teores de arabinose e xilose em membranas lavadas com água decresceram significativamente durante o osmocondicionamento. A galactose não foi detectada na membrana em 120 horas. A arabinose mostrou ser a principal constituinte da membrana. A atividade de a-galactosidase mostrou diferença significativa durante o período de 120 horas. Os teores de ramnose, arabinose e xilose alteraram-se significativamente na fração péctica, enquanto a ramnose foi a única na fração hemicelulósica. A glicose foi detectada somente nessa última fração. Os teores de glicose no embrião e cotilédones alteraram-se significativamente durante o osmocondicionamento. Os teores de estaquiose e de rafinose não tiveram alterações significativas nos cotilédones, enquanto o de sacarose reduziu-se significativamente, mantendo-se mais alto do que os dos outros dois oligossacarídeos. O teor de proteína decresceu significativamente nas 120 horas de

78 FR 16208 - Safety Zone; V. I. Carnival Finale; St. Thomas Harbor; St. Thomas, U.S. Virgin Islands

Science.gov (United States)

2013-03-14

... 1625-AA00 Safety Zone; V. I. Carnival Finale; St. Thomas Harbor; St. Thomas, U.S. Virgin Islands AGENCY... establish a safety zone on the waters of St. Thomas Harbor in St. Thomas, U. S. Virgin Islands during the V... between 9 a.m. and 5 p.m., Monday through Friday, except federal holidays. The telephone number is 202-366...

St. Lucia.

Science.gov (United States)

1987-06-01

The population of St Lucia was 123,000 in 1986, with an annual growth rate of 2%. The infant mortality rate stands at 22.2/1000 live births, and life expectancy is 70.3 years for males and 74.9 years for females. The literacy rate is 78%. St Lucia's labor force is allocated as follows: agriculture, 36.6%; industry and commerce, 20.1%; and services, 18.1%. The gross national product (GNP) was US$146 million in 1985, with an annual growth rate of 3% and a per capita GNP of $1071. St Lucia is a parliamentary democracy modeled on the British Westminster system. The island is divided into 16 parishes and 1 urban area (the capital, Castries). St Lucia is currently a politically stable country, although the high level of youth unemployment is a cause for concern. Ongoing stability may depend on the government's ability to provide services such as jobs and housing. The economy has evolved from a monocrop sugar plantation type to a diversified economy based on agriculture, industry, and tourism. Agriculture, dominated by the banana industry, is characterized by the participation of a large number of small and medium-sized enterprises. Industry is being encouraged through the provision of incentives such as tax rebates. The government is attempting to maintain a sound investment climate through a tripartite dialogue with the private sector and trade unions. Overall economic policy is predicated on the attraction of sound investments, by both local and foreign entities, to accelerate the rate of economic growth, solve the unemployment problem, and generate a solid balance-of-payments position.

Development of HANARO ST3 shield

International Nuclear Information System (INIS)

Park, K. N.; Lee, J. S.; Shim, H. S.

2004-12-01

This report contains the design, fabrication and accurate installation of ST3 shield, which would be installed at ST3 beam port of HANARO. At first, we designed and fabricated ST3 shield casemate composed of 14 blocks. We filled it with heavy concrete, lead ingot and polyethylene that mixed B 4 C powder and epoxy. The average filling density of total shield casemate was 4.7g/cm 3 . The developed ST3 shield was installed at the ST3 beam port and the accuracy of installation for each beam path and channel was evaluated. We found that the extraction of neutron beam to meet the requirement of neutron spectrometer is possible. Also, we developed ancillary equipment such as BGU, quick shutter and exterior shield door for the effective opening and closing of neutron beam. As a result of this study, it was found that neutron spectrometer such as neutron reflectometer and high intensity powder diffractomater can be installed at the ST3 beam port

Teknisk Ståbi

DEFF Research Database (Denmark)

Teknisk Ståbi er de bygningsprojekterendes og entreprenørers håndbog. Den dækker matematik, fysik, statestik, laster og sikkerhed samt beggematerialerne: beton, stål, træ, murværk, letbeton, glas og endelig fundering. Denne udgave er en næsten totalrevision, baseret på de nye Eurocodes, der afløs...

The marine Algal Vegetation of St. Martin, St. Eustatius and Saba (Netherlands Antilles)

NARCIS (Netherlands)

Vroman, M.

1968-01-01

Along the coast of St. Martin, St. Eustatius and Saba the rocks above sea-level often show a number of differently coloured zones. This is clearly visible when the coast over a larger distance is formed by one type of rock, as for instance on Saba. In many places a light-coloured belt is seen above

75 FR 38723 - Safety Zone; St. Ignace 4th of July Fireworks, East Moran Bay, Lake Huron, St. Ignace, MI

Science.gov (United States)

2010-07-06

...-AA00 Safety Zone; St. Ignace 4th of July Fireworks, East Moran Bay, Lake Huron, St. Ignace, MI AGENCY... safety zone on East Moran Bay, Lake Huron, St. Ignace, Michigan. This zone is intended to restrict vessels from a portion of East Moran Bay during the St. Ignace 4th of July Fireworks display, July 4, 2010...

The Role of the st313-td Gene in Virulence of Salmonella Typhimurium ST313

DEFF Research Database (Denmark)

Herrero-Fresno, Ana; Wallrodt, Inke; Leekitcharoenphon, Pimlapas

2014-01-01

Multidrug-resistant Salmonella enterica serovar Typhimurium ST313 has emerged in sub-Saharan Africa causing severe infections in humans. Therefore, it has been speculated that this specific sequence type, ST313, carries factors associated with increased pathogenicity. We assessed the role in viru...

ST-intuitionistic fuzzy metric space with properties

Science.gov (United States)

Arora, Sahil; Kumar, Tanuj

2017-07-01

In this paper, we define ST-intuitionistic fuzzy metric space and the notion of convergence and completeness properties of cauchy sequences is studied. Further, we prove some properties of ST-intuitionistic fuzzy metric space. Finally, we introduce the concept of symmetric ST Intuitionistic Fuzzy metric space.

Chemical Composition of the Essential Oils of Three Thymus Taxa from Turkey with Antimicrobial and Antioxidant Activities

Directory of Open Access Journals (Sweden)

F. Zehra Küçükbay

2014-03-01

Full Text Available GC-MS analysis of the essential oils from aerial parts of Thymus migricus Klokov & Des.-Shost, Thymus fallax Fisch. & Mey. and Thymus pubescens Boiss. & Kotschy ex Celak var. pubescens resulted in the identification of 26, 35 and 53 constituents, respectively. The major components in the essential oil of T. migricus were found to be α-terpineol (30.6%, thymol (20.7% and α-terpinyl acetate (14.9% while in the essentiol oil of T. fallaxcis-carveol (29.6% and α-terpineol (10.8%. Carvacrol was a dominant compound with a percentage 66.1% of the essential oil of T. pubescens var. pubescens. The data obtained indicate that the essential oils of Thymus species generally exhibit some bacteriostatic activity. The antioxidant activity of the tested essential oils were found to be slightly lower than butylatedhydroxyanisole (BHA.

Henkilöstövoimavarojen johtamista megamarketissa

OpenAIRE

Setälä, Minna

2016-01-01

Henkilöstö on lähes kaikkien organisaatioiden tärkein voimavara ja menestyksen perusta. Ilman henkilöstön olemassaoloa ja osaamista, ei mikään organisaatio pystyisi toimimaan. Henkilöstövoimavarojen johtamisen tulisikin olla keskeinen osa yrityksen strategista toimintaa. Osaava ja hyvinvoiva henkilöstö tuottaa luonnollisesti vastinetta siihen sijoitetulle pääomalle. Tämä opinnäytetyö tehtiin Vantaalla sijaitsevalle elintarvike- ja päivittäistavaraketjun myymälälle, supermarketille. Tavo...

Baseline risk assessment for exposure to contaminants at the St. Louis Site, St. Louis, Missouri

International Nuclear Information System (INIS)

1993-11-01

The St. Louis Site comprises three noncontiguous areas in and near St. Louis, Missouri: the St. Louis Downtown Site (SLDS), the St. Louis Airport Storage Site (SLAPS), and the Latty Avenue Properties. The main site of the Latty Avenue Properties includes the Hazelwood Interim Storage Site (HISS) and the Futura Coatings property, which are located at 9200 Latty Avenue. Contamination at the St. Louis Site is the result of uranium processing and disposal activities that took place from the 1940s through the 1970s. Uranium processing took place at the SLDS from 1942 through 1957. From the 1940s through the 1960s, SLAPS was used as a storage area for residues from the manufacturing operations at SLDS. The materials stored at SLAPS were bought by Continental Mining and Milling Company of Chicago, Illinois, in 1966, and moved to the HISS/Futura Coatings property at 9200 Latty Avenue. Vicinity properties became contaminated as a result of transport and movement of the contaminated material among SLDS, SLAPS, and the 9200 Latty Avenue property. This contamination led to the SLAPS, HISS, and Futura Coatings properties being placed on the National Priorities List (NPL) of the US Environmental Protection Agency (EPA). The US Department of Energy (DOE) is responsible for cleanup activities at the St. Louis Site under its Formerly Utilized Sites Remedial Action Program (FUSRAP). The primary goal of FUSRAP is the elimination of potential hazards to human health and the environment at former Manhattan Engineer District/Atomic Energy Commission (MED/AEC) sites so that, to the extent possible, these properties can be released for use without restrictions. To determine and establish cleanup goals for the St. Louis Site, DOE is currently preparing a remedial investigation/feasibility study-environmental impact statement (RI/FS-EIS). This baseline risk assessment (BRA) is a component of the process; it addresses potential risk to human health and the environment associated wi

Herrens röst

DEFF Research Database (Denmark)

Rösing, Lilian Munk

2015-01-01

Om språket är gränsen mellan djur och människor, vad innebär det när hundar talar? I filmen Upp pratar de animerade hundarna, men med sin husses röst. Lilian Munk Rösing ser filmen i sällskap av bland andra Jacques Lacan, Slavoj Žižek och Renata Salecl och finner en röst utan kropp, en kropp besj...

Differences in symptoms, first medical contact and pre-hospital delay times between patients with ST- and non-ST-elevation myocardial infarction.

Science.gov (United States)

Ängerud, Karin H; Sederholm Lawesson, Sofia; Isaksson, Rose-Marie; Thylén, Ingela; Swahn, Eva

2017-11-01

In ST-elevation myocardial infarction, time to reperfusion is crucial for the prognosis. Symptom presentation in myocardial infarction influences pre-hospital delay times but studies about differences in symptoms between patients with ST-elevation myocardial infarction and non-ST-elevation myocardial infarction are sparse and inconclusive. The aim was to compare symptoms, first medical contact and pre-hospital delay times in patients with ST-elevation myocardial infarction and non-ST-elevation myocardial infarction. This multicentre, observational study included 694 myocardial infarction patients from five hospitals. The patients filled in a questionnaire about their pre-hospital experiences within 24 h of hospital admittance. Chest pain was the most common symptom in ST-elevation myocardial infarction and non-ST-elevation myocardial infarction (88.7 vs 87.0%, p=0.56). Patients with cold sweat (odds ratio 3.61, 95% confidence interval 2.29-5.70), jaw pain (odds ratio 2.41, 95% confidence interval 1.04-5.58), and nausea (odds ratio 1.70, 95% confidence interval 1.01-2.87) were more likely to present with ST-elevation myocardial infarction, whereas the opposite was true for symptoms that come and go (odds ratio 0.58, 95% confidence interval 0.38-0.90) or anxiety (odds ratio 0.52, 95% confidence interval 0.29-0.92). Use of emergency medical services was higher among patients admitted with ST-elevation myocardial infarction. The pre-hospital delay time from symptom onset to first medical contact was significantly longer in non-ST-elevation myocardial infarction (2:05 h vs 1:10 h, p=0.001). Patients with ST-elevation myocardial infarction differed from those with non-ST-elevation myocardial infarction regarding symptom presentation, ambulance utilisation and pre-hospital delay times. This knowledge is important to be aware of for all healthcare personnel and the general public especially in order to recognise symptoms suggestive of ST-elevation myocardial infarction and

Centrosema pubescens

African Journals Online (AJOL)

HP USER

to degrade fibrous feedstuffs and express their nutrient both to the host ... identified using a white nylon thread bearing a plastic plate at one ... forage fraction degraded in the rumen. ..... bacteria, especially when high concentrate (> 50%) diets.

Identification and characterization of two novel cytosolic sulfotransferases, SULT1 ST7 and SULT1 ST8, from zebrafish

Energy Technology Data Exchange (ETDEWEB)

Liu, T.-A. [Department of Pharmacology, College of Pharmacy, University of Toledo, Toledo, OH 43606 (United States); Department of Biological Science and Technology, College of Biological Science and Technology, National Chiao Tung University, Hsinchu, Taiwan (China); Bhuiyan, Shakhawat [Division of Arts and Sciences, Jarvis Christian College, Hawkins, TX 75765 (United States); Snow, Rhodora [School of Mathematics and Science, J. Sargeant Reynolds Community College, Richmond, VA 23285 (United States); Yasuda, Shin; Yasuda, Tomoko [Department of Pharmacology, College of Pharmacy, University of Toledo, Toledo, OH 43606 (United States); Yang, Y.-S. [Department of Biological Science and Technology, College of Biological Science and Technology, National Chiao Tung University, Hsinchu, Taiwan (China); Williams, Frederick E.; Liu, M.-Y.; Suiko, Masahito [Department of Pharmacology, College of Pharmacy, University of Toledo, Toledo, OH 43606 (United States); Carter, Glendora [School of Mathematics and Science, J. Sargeant Reynolds Community College, Richmond, VA 23285 (United States); Liu, M.-C. [Department of Pharmacology, College of Pharmacy, University of Toledo, Toledo, OH 43606 (United States)], E-mail: ming.liu@utoledo.edu

2008-08-29

Cytosolic sulfotransferases (SULTs) constitute a family of Phase II detoxification enzymes that are involved in the protection against potentially harmful xenobiotics as well as the regulation and homeostasis of endogenous compounds. Compared with humans and rodents, the zebrafish serves as an excellent model for studying the role of SULTs in the detoxification of environmental pollutants including environmental estrogens. By searching the expressed sequence tag database, two zebrafish cDNAs encoding putative SULTs were identified. Sequence analysis indicated that these two putative zebrafish SULTs belong to the SULT1 gene family. The recombinant form of these two novel zebrafish SULTs, designated SULT1 ST7 and SULT1 ST8, were expressed using the pGEX-2TK glutathione S-transferase (GST) gene fusion system and purified from transformed BL21 (DE3) cells. Purified GST-fusion protein form of SULT1 ST7 and SULT1 ST8 exhibited strong sulfating activities toward environmental estrogens, particularly hydroxylated polychlorinated biphenyls (PCBs), among various endogenous and xenobiotic compounds tested as substrates. pH-dependence experiments showed that SULT1 ST7 and SULT1 ST8 displayed pH optima at 6.5 and 8.0, respectively. Kinetic parameters of the two enzymes in catalyzing the sulfation of catechin and chlorogenic acid as well as 3-chloro-4-biphenylol were determined. Developmental expression experiments revealed distinct patterns of expression of SULT1 ST7 and SULT1 ST8 during embryonic development and throughout the larval stage onto maturity.

St. James marine terminal facility description

Energy Technology Data Exchange (ETDEWEB)

1993-10-01

The US Department of Energy (DOE) currently owns and operates a marine terminal on the west bank of the Mississippi River at St. James, Louisiana. The St. James facility was constructed by the Department to provide marine services associated with the fill and drawdown of the Strategic Petroleum Reserve (SPR) crude oil storage facilities located at Bayou Choctaw and Weeks Island, Louisiana. Although strategic to the mission of the SPR in the event of a national emergency, the St. James terminal is situated such that it has a high potential to also serve the commercial industry`s needs for crude oil terminalling and storage. The St. James terminal is located approximately 45 miles west of New Orleans and 30 miles southeast of Baton Rouge, and approximately 160 miles upstream from the mouth of the Mississippi River. Construction of the St. James terminal was initiated in 1978 and was completed in 1980. Since then, the terminal has received and transferred over 125 million barrels of crude oil to the SPR sites for storage. For crude oil distribution, the St. James terminal was connected to the neighboring LOCAP terminal by a 0.1 mile 36-inch pipeline in 1981 and to the Capline terminal by a 0.5 mile 30-inch pipeline in 1988. The terminal also has a 30-inch pipeline connection to the Koch oil terminal which was used for initial fill purposes; however, this pipeline has been disconnected and is currently inactive. A complete description of the St. James terminal facilities, operational capabilities, operational certifications, and future Government requirements are presented in Sections 2, 3, 4, and 5 respectively.

Meteor detection on ST (MST) radars

International Nuclear Information System (INIS)

Avery, S.K.

1987-01-01

The ability to detect radar echoes from backscatter due to turbulent irregularities of the radio refractive index in the clear atmosphere has lead to an increasing number of established mesosphere - stratosphere - troposphere (MST or ST) radars. Humidity and temperature variations are responsible for the echo in the troposphere and stratosphere and turbulence acting on electron density gradients provides the echo in the mesosphere. The MST radar and its smaller version, the ST radar, are pulsed Doppler radars operating in the VHF - UHF frequency range. These echoes can be used to determine upper atmosphere winds at little extra cost to the ST radar configuration. In addition, the meteor echoes can supplement mesospheric data from an MST radar. The detection techniques required on the ST radar for delineating meteor echo returns are described

Stereospecificity (ST) of the microsomal ethanol oxidizing system (MEOS)

International Nuclear Information System (INIS)

Alderman, J.; Kato, S.; Lasker, J.; Lieber, C.S.

1987-01-01

The ST of MEOS for the ethanol 1R hydrogen has been variously reported as absolute, partial or absent, with free radical involvement postulated in the latter case. To determine both the ST of MEOS and the participation of free radicals in the reaction, they investigated MEOS ST using 1R[1- 3 H] ethanol as substrate. ST is expressed as the fraction of 3 H labeling in acetaldehyde formed, relative to that in ethanol, and ranges from 0.5 to 0. Partial ST was observed using liver microsomes from both rats and hamsters; it significantly decreased after ethanol feeding. 0.1 mM desferrioxamine (dfx) did not increase ST in any of these microsomal preparations while ferric EDTA decreased it, suggesting that ethanol treatment induces a cytochrome P-450 with lower ST rather than increasing free radical involvement. This is supported by a virtual absence of ST observed in a reconstituted system containing purified hamster P-450/sub ALC/, a liver cytochrome P-450 isozyme induced in hamsters by ethanol treatment. Their results indicate that, unlike other enzymes that oxidize ethanol, MEOS has only partial ST. Thus, ST alone cannot be used as an index of free radical involvement but, when evaluated with the response of ST to dfx, it indicated that MEOS is unlikely to involve free radical attack on ethanol in solution

Reciprocal ST-Segment Changes in Myocardial Infarction: Ischemia at Distance Versus Mirror Reflection of ST-Elevation.

Science.gov (United States)

Vaidya, Gaurang Nandkishor; Antoine, Steve; Imam, Syed Haider; Kozman, Hani; Smulyan, Harold; Villarreal, Daniel

2018-02-01

Reciprocal ST-depression in the electrocardiograms (ECGs) of patients with ST-elevation myocardial infarction (STEMI) results from either true ischemia at a distance via collateral circulation diverting blood to the infarcted region or an electrical phenomenon that results from a mirror reflection of ST-elevation. We aimed to identify the role of reciprocal ECG changes in predicting collateral circulation to the infarcted area determined angiographically. In a retrospective study, ECG and angiography of 53 STEMI patients admitted to SUNY Upstate Medical University in 2014 were reviewed independently by experts blinded to the results of ECG and coronary angiography. Reciprocal changes (RC) in ECG were present in 41 patients (77%) and on angiography, 14 patients (26%) exhibited collateral vessels to the ischemic areas. No correlation was found between the presence of RC and collateral circulation (P = 0.384), or between the depth of reciprocal ST-depression and the degree of the collateral circulation (P = 0.195). However, 84% of patients without collaterals exhibited resolution of RC after successful percutaneous coronary intervention (PCI) (P = 0.036), suggesting that the ST depressions that resolved after reperfusion were directly caused by the culprit vessel. Patients without RC presented late after symptom onset (9.25 versus 3.83 hours, P = 0.004), also suggesting time related resolution. RC had no relation to or predictive value for collaterals on angiography. Among late presenting patients, RC were less frequent. Thus, reciprocal ST-depression may represent subendocardial ischemia from the primary coronary event or simply an electrical phenomenon, rather than ischemia at distance from impaired collateral circulation. Published by Elsevier Inc.

Firmaets Største Bedrift

DEFF Research Database (Denmark)

Hansen, Peer Henrik

fortæller, hvordan de tidligere modstandsfolk Arne Sejr og Niels Frommelt få år efter befrielsen etablerede deres såkaldte Firma for med støtte fra ledende danske politikere, Forsvarets Efterretningstjeneste og CIA at organisere en hemmelig krig mod Sovjetunionens danske støtter. Meget tyder på, at både...

Escherichia coli ST131, an Intriguing Clonal Group

Science.gov (United States)

Bertrand, Xavier; Madec, Jean-Yves

2014-01-01

SUMMARY In 2008, a previously unknown Escherichia coli clonal group, sequence type 131 (ST131), was identified on three continents. Today, ST131 is the predominant E. coli lineage among extraintestinal pathogenic E. coli (ExPEC) isolates worldwide. Retrospective studies have suggested that it may originally have risen to prominence as early as 2003. Unlike other classical group B2 ExPEC isolates, ST131 isolates are commonly reported to produce extended-spectrum β-lactamases, such as CTX-M-15, and almost all are resistant to fluoroquinolones. Moreover, ST131 E. coli isolates are considered to be truly pathogenic, due to the spectrum of infections they cause in both community and hospital settings and the large number of virulence-associated genes they contain. ST131 isolates therefore seem to contradict the widely held view that high levels of antimicrobial resistance are necessarily associated with a fitness cost leading to a decrease in pathogenesis. Six years after the first description of E. coli ST131, this review outlines the principal traits of ST131 clonal group isolates, based on the growing body of published data, and highlights what is currently known and what we need to find out to provide public health authorities with better information to help combat ST131. PMID:24982321

Role of myocardial ischemia on exercise-induced ST elevation

International Nuclear Information System (INIS)

Saito, Muneyasu; Sumiyoshi, Tetsuya; Nishimura, Tsunehiko; Uehara, Toshiisa; Hayashida, Kouhei; Haze, Kazuo; Fukami, Ken-ichi; Hiramori, Katsuhiko

1986-01-01

Exercise-induced ST elevation in patients with previous myocardial infarction (MI) has been recognized to be related to left ventricular (LV) asynergy, however it is also recognized that myocardial ischemia can induce ST elevation. In this study, factors which determine the extent of ST elevation, with special reference to myocardial ischemia, was re-evaluated using quantitative analysis of stress myocardial scintigraphy (S-SG). Among 65 patients with previous anterior myocardial infarction and documented single vessel disease of left anterior descending artery (LAD), 19 patients who had exercise-induced ST elevation (ΔST ≥ 2.0 mm) had more abnormal Q waves (p < 0.01), lower LV ejection fraction (EF) (p < 0.01), more severe LV asynergy (p < 0.05) and less incidence of post-MI angina pectoris (AP) (p < 0.01), compared to those with ΔST < 2.0 mm, indicating that ST elevation is primarily related to LV asynergy. Correlation studies among clinical, angiographic and scintigraphic parameters show that ΔST was significantly related to a size of MI represented by Tl score or relative defect Tl activity and number of abnormal Q waves (No.Q), the magnitude of work load expressed by changes in double product (ΔDP) and intervals between the onset and exercise test, as well as myocardial ischemia expressed by the extent of redistribution (%RD) in S-SG. Among 23 patients with post-MI AP, ΔST significantly correlated with %RD (r = 0.47), indicating that myocardial ischemia can be a mechanism of exercise-induced ST elevation in patients with previous MI. Furtheremore, among those with ST elevation, concave-type ST elevation was more related to myocardial ischemia compared to convex-type ST elevation as expressed by the incidence of post-MI AP and/or significant redistribution. (J.P.N.)

21st Century Skills Map: Geography

Science.gov (United States)

Partnership for 21st Century Skills, 2009

2009-01-01

This 21st Century Skills Map is the result of hundreds of hours of research, development and feedback from educators and business leaders across the nation. The Partnership for 21st Century Skills has issued this map for the core subject of Geography.

ST Elevation in aVR with Coexistent Multilead ST Depression

Directory of Open Access Journals (Sweden)

Benjamin Cooper

2017-01-01

Full Text Available History of present illness: An 80-year-old female with a history of Crohn’s disease presented to the emergency department with chest pain. She had two weeks of exertional chest pain that preceded an episode of chest pain immediately prior to arrival associated with diaphoresis. Her pain nearly completely resolved with sublingual nitroglycerin provided by pre-hospital personnel. She was hemodynamically stable with normal vital signs on arrival. An ECG was immediately obtained. Significant findings: The ECG shows ST-segment depressions in precordial leads V3 through V6, and limb leads I, II, and aVL, and 1 mm of ST-segment elevation in aVR. The initial troponin I was elevated at 1.37 ng/mL (upper limit of normal 0.40. Cardiology decided to delay catheterization until the next day when diffuse coronary disease was discovered (including 90% of the left circumflex stenosis, 60% proximal and 75% mid-left anterior descending stenosis, 75% third diagonal branch stenosis, and 90% posterior descending artery stenosis. The following day, the patient went to the operating room for coronary artery bypass grafting (CABG. Discussion: Traditionally, lead aVR has not received attention when interpreting acutely ischemic changes on ECG, leading some to refer to it as “the forgotten lead.”1 Current guidelines acknowledge the significance of multilead ST depression with coexistent ST elevation in aVR, and this pattern has been identified as the strongest predictor of severe left main coronary artery and/or 3-vessel disease (LM/3VD.2-3 When this ECG pattern is recognized in patients with ischemic symptoms, the emergency physician should involve cardiology early. When managing patients with suspected LM/3VD, it is important to withhold dual anti-platelet therapy as CABG is likely to be indicated,1,3 and guidelines recommend discontinuing P2Y12 inhibitors like clopidogrel or ticagrelor at least 24 hours prior to urgent CABG.2

The cognitive status of stød

DEFF Research Database (Denmark)

Clausen, Sara Juul; Kristensen, Line Burholt

2015-01-01

marked. Keeping in mind the cross-distribution between phonetic/phonological markedness and distributional patterns, we investigate here whether stød is also related to accent 1 when it comes to cognitive markedness. We present the results of a psycholinguistic study in which participants attended...... for words with non-stød stems, indicating that the cognitive markedness status of stød corresponds to that of accent 2....

Spot Støjbergs støj

DEFF Research Database (Denmark)

Kock, Christian Erik J

2015-01-01

Inger Støjberg er placeret på en af de mest profilerede poster i Løkkes regering. Spørger du hende om fortiden, taler hun om fremtiden. Spørger du hende om fremtiden, taler hun om fortiden. Ergo: Hun taler udenom, og hun er god til det. Hun er så god, at det skader demokratiet. Lær at spotte hend...

VaST: A variability search toolkit

Science.gov (United States)

Sokolovsky, K. V.; Lebedev, A. A.

2018-01-01

Variability Search Toolkit (VaST) is a software package designed to find variable objects in a series of sky images. It can be run from a script or interactively using its graphical interface. VaST relies on source list matching as opposed to image subtraction. SExtractor is used to generate source lists and perform aperture or PSF-fitting photometry (with PSFEx). Variability indices that characterize scatter and smoothness of a lightcurve are computed for all objects. Candidate variables are identified as objects having high variability index values compared to other objects of similar brightness. The two distinguishing features of VaST are its ability to perform accurate aperture photometry of images obtained with non-linear detectors and handle complex image distortions. The software has been successfully applied to images obtained with telescopes ranging from 0.08 to 2.5 m in diameter equipped with a variety of detectors including CCD, CMOS, MIC and photographic plates. About 1800 variable stars have been discovered with VaST. It is used as a transient detection engine in the New Milky Way (NMW) nova patrol. The code is written in C and can be easily compiled on the majority of UNIX-like systems. VaST is free software available at http://scan.sai.msu.ru/vast/.

Chicago-St. Louis high speed rail plan

International Nuclear Information System (INIS)

Stead, M.E.

1994-01-01

The Illinois Department of Transportation (IDOT), in cooperation with Amtrak, undertook the Chicago-St. Louis High Speed Rail Financial and Implementation Plan study in order to develop a realistic and achievable blueprint for implementation of high speed rail in the Chicago-St. Louis corridor. This report presents a summary of the Price Waterhouse Project Team's analysis and the Financial and Implementation Plan for implementing high speed rail service in the Chicago-St. Louis corridor

Chicago-St. Louis high speed rail plan

Energy Technology Data Exchange (ETDEWEB)

Stead, M.E.

1994-12-31

The Illinois Department of Transportation (IDOT), in cooperation with Amtrak, undertook the Chicago-St. Louis High Speed Rail Financial and Implementation Plan study in order to develop a realistic and achievable blueprint for implementation of high speed rail in the Chicago-St. Louis corridor. This report presents a summary of the Price Waterhouse Project Team`s analysis and the Financial and Implementation Plan for implementing high speed rail service in the Chicago-St. Louis corridor.

Data Abstraction Mechanisms in Sina/st

NARCIS (Netherlands)

Meyrowitz, N.K.; Aksit, Mehmet; Tripathi, Anand

1988-01-01

This paper describes a new data abstraction mechanism in an object-oriented model of computing. The data abstraction mechanism described here has been devised in the context of the design of Sina/st language. In Sina/st no language constructs have been adopted for specifying inheritance or

Pretreatment with soluble ST2 reduces warm hepatic ischemia/reperfusion injury

International Nuclear Information System (INIS)

Yin Hui; Huang Baojun; Yang Heng; Huang Yafei; Xiong Ping; Zheng Fang; Chen Xiaoping; Chen Yifa; Gong Feili

2006-01-01

The interleukin-1 receptor-like protein ST2 exists in both membrane-bound (ST2L) and soluble form (sST2). ST2L has been found to play an important regulatory role in Th2-type immune response, but the function of soluble form of ST2 remains to be elucidated. In this study, we report the protective effect of soluble ST2 on warm hepatic ischemia/reperfusion injury. We constructed a eukaryotic expression plasmid, psST2-Fc, which expresses functional murine soluble ST2-human IgG1 Fc (sST2-Fc) fusion protein. The liver damage after ischemia/reperfusion was significantly attenuated by the expression of this plasmid in vivo. sST2-Fc remarkably inhibited the activation of Kupffer cells and the production of proinflammatory mediators TNF-α and IL-6. Furthermore, the levels of TLR4 mRNA and the nuclear translocation of NF-κB were also suppressed by pretreatment with sST2-Fc. These results thus identified soluble ST2 as a negative regulator in hepatic I/R injury, possibly via ST2-TLR4 pathway

ST segment/heart rate slope as a predictor of coronary artery disease: comparison with quantitative thallium imaging and conventional ST segment criteria

International Nuclear Information System (INIS)

Finkelhor, R.S.; Newhouse, K.E.; Vrobel, T.R.; Miron, S.D.; Bahler, R.C.

1986-01-01

The ST segment shift relative to exercise-induced increments in heart rate, the ST/heart rate slope (ST/HR slope), has been proposed as a more accurate ECG criterion for diagnosing significant coronary artery disease (CAD). Its clinical utility, with the use of a standard treadmill protocol, was compared with quantitative stress thallium (TI) and standard treadmill criteria in 64 unselected patients who underwent coronary angiography. The overall diagnostic accuracy of the ST/HR slope was an improvement over TI and conventional ST criteria (81%, 67%, and 69%). For patients failing to reach 85% of their age-predicted maximal heart rate, its diagnostic accuracy was comparable with TI (77% and 74%). Its sensitivity in patients without prior myocardial infarctions was equivalent to that of thallium (91% and 95%). The ST/HR slope was directly related to the angiographic severity (Gensini score) of CAD in patients without a prior infarction (r = 0.61, p less than 0.001). The ST/HR slope was an improved ECG criterion for diagnosing CAD and compared favorably with TI imaging

E-st@r-I experience: Valuable knowledge for improving the e-st@r-II design

Science.gov (United States)

Corpino, S.; Obiols-Rabasa, G.; Mozzillo, R.; Nichele, F.

2016-04-01

Many universities all over the world have now established hands-on education programs based on CubeSats. These small and cheap platforms are becoming more and more attractive also for other-than-educational missions, such as technology demonstration, science applications, and Earth observation. This new paradigm requires the development of adequate technology to increase CubeSat performance and mission reliability, because educationally-driven missions have often failed. In 2013 the ESA Education Office launched the Fly Your Satellite! Programme which aims at increasing CubeSat mission reliability through several actions: to improve design implementation, to define best practices for conducting the verification process, and to make the CubeSat community aware of the importance of verification. Within this framework, the CubeSat team at Politecnico di Torino developed the e-st@r-II CubeSat as follow-on of the e-st@r-I satellite, launched in 2012 on the VEGA Maiden Flight. E-st@r-I and e-st@r-II are both 1U satellites with educational and technology demonstration objectives: to give hands-on experience to university students and to test an active attitude determination and control system based on inertial and magnetic measurements with magnetic actuation. This paper describes the know-how gained thanks to the e-st@r-I mission, and how this heritage has been translated into the improvement of the new CubeSat in several areas and lifecycle phases. The CubeSat design has been reviewed to reduce the complexity of the assembly procedure and to deal with possible failures of the on-board computer, for example re-coding the software in the communications subsystem. New procedures have been designed and assessed for the verification campaign accordingly to ECSS rules and with the support of ESA specialists. Different operative modes have been implemented to handle some anomalies observed during the operations of the first satellite. A new version of the on-board software is

Electrocardiogram ST-Segment Morphology Delineation Method Using Orthogonal Transformations.

Directory of Open Access Journals (Sweden)

Miha Amon

Full Text Available Differentiation between ischaemic and non-ischaemic transient ST segment events of long term ambulatory electrocardiograms is a persisting weakness in present ischaemia detection systems. Traditional ST segment level measuring is not a sufficiently precise technique due to the single point of measurement and severe noise which is often present. We developed a robust noise resistant orthogonal-transformation based delineation method, which allows tracing the shape of transient ST segment morphology changes from the entire ST segment in terms of diagnostic and morphologic feature-vector time series, and also allows further analysis. For these purposes, we developed a new Legendre Polynomials based Transformation (LPT of ST segment. Its basis functions have similar shapes to typical transient changes of ST segment morphology categories during myocardial ischaemia (level, slope and scooping, thus providing direct insight into the types of time domain morphology changes through the LPT feature-vector space. We also generated new Karhunen and Lo ève Transformation (KLT ST segment basis functions using a robust covariance matrix constructed from the ST segment pattern vectors derived from the Long Term ST Database (LTST DB. As for the delineation of significant transient ischaemic and non-ischaemic ST segment episodes, we present a study on the representation of transient ST segment morphology categories, and an evaluation study on the classification power of the KLT- and LPT-based feature vectors to classify between ischaemic and non-ischaemic ST segment episodes of the LTST DB. Classification accuracy using the KLT and LPT feature vectors was 90% and 82%, respectively, when using the k-Nearest Neighbors (k = 3 classifier and 10-fold cross-validation. New sets of feature-vector time series for both transformations were derived for the records of the LTST DB which is freely available on the PhysioNet website and were contributed to the LTST DB. The

Home of the 151st Air Refueling Wing

Science.gov (United States)

History HRA Alley Public Affairs SAPR Units Contact Us Search 151st ARW: 151st ARW The Roland R. Wright woman in the profession of arms President Trump visits Roland R. Wright Air National Guard Base 151st Commentaries Women's History Month: looking around as important as looking back Veterans Day: Pay tribute with

Phytochemical Evaluation of Wild and Cultivated Pepper (Capsicum annuum L. and C. pubescens Ruiz & Pav. from Oaxaca, Mexico Evaluación Fitoquímica en Chile (Capsicum annuum L. and C. pubescens Ruiz & Pav. Silvestre y Cultivado en Oaxaca, México

Directory of Open Access Journals (Sweden)

Araceli Minerva Vera-Guzmán

2011-12-01

positivamente con el contenido de fenoles totales y flavonoides. Los morfotipos evaluados difieren en el contenido de capsaicina y dihidrocapsaicina, en C. annuum fue mayor la cantidad de capsaicina (4.9 a 142 pig mL-1 que de dihidrocapsaicina (1.5 a 65.5 pg mL-1 y en C. pubescens Ruiz & Pav. el patrón fue inverso.

St. Louis Airport site environmental report for calendar year 1989, St. Louis, Missouri

Energy Technology Data Exchange (ETDEWEB)

none,

1990-05-01

The environmental monitoring program, which began in 1984, continued during 1989 at the St. Louis Airport Site (SLAPS) in St. Louis County, Missouri. SLAPS and its vicinity properties, including ditches north and south of the site, were designated for cleanup as part of the Formerly Utilized Sites Remedial Action Program (FUSRAP), a United States Department of Energy (DOE) program to identify and decontaminate or otherwise control sites where residual radioactive material remains from the early years of the nation's atomic energy program. The monitoring program at SLAPS measures radon concentrations in air; external gamma dose rates; and uranium, thorium, and radium concentrations in surface water, groundwater, and sediment. Additionally, several nonradiological parameters are measured in groundwater. To assess the potential effect of SLAPS on public health, the potential radiation dose was estimated for a hypothetical maximally exposed individual. This report presents the findings of the environmental monitoring program conducted at the St. Louis Airport Site (SLAPS) during calendar year 1989. 19 refs., 13 figs., 14 tabs.

Virulence of invasive Salmonella Typhimurium ST313 in animal models of infection.

Directory of Open Access Journals (Sweden)

Girish Ramachandran

2017-08-01

Full Text Available Salmonella Typhimurium sequence type (ST 313 produces septicemia in infants in sub-Saharan Africa. Although there are known genetic and phenotypic differences between ST313 strains and gastroenteritis-associated ST19 strains, conflicting data about the in vivo virulence of ST313 strains have been reported. To resolve these differences, we tested clinical Salmonella Typhimurium ST313 and ST19 strains in murine and rhesus macaque infection models. The 50% lethal dose (LD50 was determined for three Salmonella Typhimurium ST19 and ST313 strains in mice. For dissemination studies, bacterial burden in organs was determined at various time-points post-challenge. Indian rhesus macaques were infected with one ST19 and one ST313 strain. Animals were monitored for clinical signs and bacterial burden and pathology were determined. The LD50 values for ST19 and ST313 infected mice were not significantly different. However, ST313-infected BALB/c mice had significantly higher bacterial numbers in blood at 24 h than ST19-infected mice. ST19-infected rhesus macaques exhibited moderate-to-severe diarrhea while ST313-infected monkeys showed no-to-mild diarrhea. ST19-infected monkeys had higher bacterial burden and increased inflammation in tissues. Our data suggest that Salmonella Typhimurium ST313 invasiveness may be investigated using mice. The non-human primate results are consistent with clinical data, suggesting that ST313 strains do not cause diarrhea.

Virulence of invasive Salmonella Typhimurium ST313 in animal models of infection.

Science.gov (United States)

Ramachandran, Girish; Panda, Aruna; Higginson, Ellen E; Ateh, Eugene; Lipsky, Michael M; Sen, Sunil; Matson, Courtney A; Permala-Booth, Jasnehta; DeTolla, Louis J; Tennant, Sharon M

2017-08-01

Salmonella Typhimurium sequence type (ST) 313 produces septicemia in infants in sub-Saharan Africa. Although there are known genetic and phenotypic differences between ST313 strains and gastroenteritis-associated ST19 strains, conflicting data about the in vivo virulence of ST313 strains have been reported. To resolve these differences, we tested clinical Salmonella Typhimurium ST313 and ST19 strains in murine and rhesus macaque infection models. The 50% lethal dose (LD50) was determined for three Salmonella Typhimurium ST19 and ST313 strains in mice. For dissemination studies, bacterial burden in organs was determined at various time-points post-challenge. Indian rhesus macaques were infected with one ST19 and one ST313 strain. Animals were monitored for clinical signs and bacterial burden and pathology were determined. The LD50 values for ST19 and ST313 infected mice were not significantly different. However, ST313-infected BALB/c mice had significantly higher bacterial numbers in blood at 24 h than ST19-infected mice. ST19-infected rhesus macaques exhibited moderate-to-severe diarrhea while ST313-infected monkeys showed no-to-mild diarrhea. ST19-infected monkeys had higher bacterial burden and increased inflammation in tissues. Our data suggest that Salmonella Typhimurium ST313 invasiveness may be investigated using mice. The non-human primate results are consistent with clinical data, suggesting that ST313 strains do not cause diarrhea.

Henkilöstötilinpäätös konsultointiyritykselle

OpenAIRE

Halmesvaara, Riikka

2010-01-01

Tämän toiminnallisen opinnäytetyön tarkoituksena oli antaa Konsultointiyritykselle kokonaiskuvaa henkilöstöstä tekemällä ilmapiirikartoitustutkimus sekä kirjallinen henkilöstötilinpäätös, joka koostui henkilöstötuloslaskelmasta ja henkilöstökertomuksesta. Työ suoritettiin tutkimuksellisena kehittämishankkeena konsultointiyritykselle. Tutkimusongelmana oli kuvata Konsultointiyrityksen osaamispääomaa ja henkilöstön rakennetta sekä luoda työkalu strategiassa määriteltyjen henkilöstöä koskevien o...

St. John's Wort (Hypericum Perforatum) and Pregnancy

Science.gov (United States)

... best live chat Live Help Fact Sheets Share St. John’s Wort (Hypericum perforatum) Tuesday, 01 May 2018 ... risk. This sheet talks about whether exposure to St. John’s Wort may increase the risk for birth ...

ST2 IN REJECTION OF THE TRANSPLANTED HEART

Directory of Open Access Journals (Sweden)

O. P. Shevchenko

2015-01-01

Full Text Available This review summarizes the current literature devoted to the analysis of prognostic role of ST2 biomarker in rejection of the transplanted heart. ST2 is one of the most promising diagnostic markers of the development and severity of heart failure as well as the mortality risk in patients with cardiovascular diseases. ST2 is expressed in cardiomyocytes in response to a variety of pathological processes and mechanical damage to the heart, which allows diagnosing cardiovascular diseases before clinical manifestations. Presumably, measuring the level of ST2 in heart transplant may have diagnostic and prognostic value in the assessment of graft and risk of rejection. Currently, accumulated clinical data on the role of given biomarker in heart transplantation are not enough, and further research on the relation of ST2 levels with different clinical and laboratory parameters in heart recipients is necessary. 

Dimensionering af stålrammebygninger mod kipning

DEFF Research Database (Denmark)

Borchersen, E.; Frederiksen, J.O.; Skov, K.

Rapporten beskriver en metode til dimensionering af stålrammebygninger mod kipning. Metoden er baseret dels på elasticitetsteoretiske overvejelser, dels på forsøg udført med 3-charniers stålrammmer i fuld skala....

GeoTIFF of 3x3 m Bathymetry for St. Thomas & St. John, 2011, UTM 20N NAD83

Data.gov (United States)

National Oceanic and Atmospheric Administration, Department of Commerce — This image represents a LiDAR (Light Detection & Ranging) 3x3 meter resolution bathymetric surface for an area of shallow seabed surrounding St. Thomas and St....

Plutonium-induced osteosarcomas in the St. Bernard

International Nuclear Information System (INIS)

Taylor, G.N.; Thurman, G.B.; Mays, C.W.; Shabestari, L.; Angus, W.; Eaton, J.; Hitchman, J.

1978-01-01

Thirteen osteosarcomas have been observed among the 7 St. Bernards that have died following the injection of 239 Pu. Preliminary data indicate that the St. Bernard is about 6 times more sensitive than the Beagle, and about 150 times more sensitive than the average person is to 239 Pu-induced bone sarcomas. Thus, the St. Bernard may be an excellent model to study the pathogenesis of bone cancer induction, to evaluate the relationship between spontaneous susceptibility and radiosensitivity, and to determine whether or not radiosensitivity significantly affects the toxicity ratio

St. Louis FUSRAP Lessons Learned

International Nuclear Information System (INIS)

Eberlin, J.; Williams, D.; Mueller, D.

2003-01-01

The purpose of this paper is to present lessons learned from fours years' experience conducting Remedial Investigation and Remedial Action activities at the St. Louis Downtown Site (SLDS) under the Formerly Utilized Sites Remedial Action Program (FUSRAP). Many FUSRAP sites are experiencing challenges conducting Remedial Actions within forecasted volume and budget estimates. The St. Louis FUSRAP lessons learned provide insight to options for cost effective remediation at FUSRAP sites. The lessons learned are focused on project planning (budget and schedule), investigation, design, and construction

21st Century Skills Map: The Arts

Science.gov (United States)

Dean, Colleen; Ebert, Christie M. Lynch; McGreevy-Nichols, Susan; Quinn, Betsy; Sabol, F. Robert; Schmid, Dale; Shauck, R. Barry; Shuler, Scott C.

2010-01-01

This 21st Century Skills Map is the result of hundreds of hours of research, development and feedback from educators and business leaders across the nation. The Partnership for 21st Century Skills has issued this map for the core subject of the Arts.

Characterisation of Australian MRSA strains ST75- and ST883-MRSA-IV and analysis of their accessory gene regulator locus.

Directory of Open Access Journals (Sweden)

Stefan Monecke

Full Text Available BACKGROUND: Community-acquired methicillin-resistant Staphylococcus aureus have become a major problem in Australia. These strains have now been isolated throughout Australia including remote Indigenous communities that have had minimal exposure to healthcare facilities. Some of these strains, belonging to sequence types ST75 and ST883, have previously been reported to harbour highly divergent alleles of the housekeeping genes used in multilocus sequence typing. METHODOLOGY/PRINCIPAL FINDINGS: ST75-MRSA-IV and ST883-MRSA-IV isolates were characterised in detail. Morphological features as well as 16S sequences were identical to other S. aureus strains. Although a partial rnpB gene sequence was not identical to previously known S. aureus sequences, it was found to be more closely related to S. aureus than to other staphylococci. Isolates also were screened using diagnostic DNA microarrays. These isolates yielded hybridisation results atypical for S. aureus. Primer directed amplification assays failed to detect species markers (femA, katA, sbi, spa. However, arbitrarily primed amplification indicated the presence of unknown alleles of these genes. Isolates could not be assigned to capsule types 1, 5 or 8. The allelic group of the accessory gene regulator (agr locus was not determinable. Sequencing of a region of agrB, agrC and agrD (approximately 2,100 bp revealed a divergent sequence. However, this sequence is more related to S. aureus agr alleles I and IV than to agr sequences from other Staphylococcus species. The predicted auto-inducing peptide (AIP sequence of ST75 was identical to that of agr group I, while the predicted AIP sequence of ST883 was identical to agr group IV. CONCLUSIONS/SIGNIFICANCE: The genetic properties of ST75/ST883-MRSA may be due to a series of evolutionary events in ancient insulated S. aureus strains including a convergent evolution leading to agr group I- or IV-like AIP sequences and a recent acquisition of SCCmec IV

Plutonium-induced osteosarcomas in the St. Bernard

International Nuclear Information System (INIS)

Taylor, G.N.; Thurman, G.B.; Mays, C.W.; Shabestari, L.; Angus, W.; Atherton, D.R.

1981-01-01

Fourteen osteosarcomas were observed among the eight St. Bernards that died following the injection of 239 Pu. Early data tentatively indicate that the St. Bernard is about 5 times more sensitive than the beagle and about 130 times more sensitive than the average person is estimated to be to 239 Pu-induced bone sarcomas. Thus the St. Bernard may be an excellent model in which to study the pathogenesis of bone cancer induction, to evaluate the relationship between spontaneous susceptibility and radiosensitivity, and to determine whether radiosensitivity significantly affects the toxicity ration of 239 Pu/ 226 Ra

St. Vicent Ferrer’s Catalán sermon on St. Martin of Tours

Directory of Open Access Journals (Sweden)

Ferreiro, Alberto

2013-12-01

Full Text Available One of the most widely venerated saints in the Middle Ages was St. Martin of Tours whose cult continues to this day in many parts of the world. In the Middle Ages, he became as popular as other major saints such as Thomas Becket, Santiago de Compostela and the Virgin Mary. St. Martin’s cult became very prominent in the Iberian Peninsula before and after the emergence of the cult of Santiago de Compostela. In St. Vicent Ferrer’s voluminous sermons this one in Catalán is dedicated to this most venerated Gallic saint. The most important late antique and early medieval sources that form the background of this sermon are by Sulpicius Severus- the Gallus and Vita Sancti Martini. In the high Middle Ages, however, his cult was popularized through the Legenda Aurea written by the Dominican Jacobus of Voragine, who synthesized Sulpicius’ two works on St. Martin. Moreover, St. Vicent preached not to make any major doctrinal breakthroughs- his main interest was to evangelize, not to write academic theology- he nevertheless exhibited great creativity. The object of this study is St. Vicent’s Catalán sermon Alius Sermo Sancti Martini, CXXXIV.Uno de los santos más venerados en la edad media fue San Martín de Tours, cuyo culto continúa hasta hoy en muchas partes del mundo. En la edad media, se hizo tan popular como otros grandes Santos: Thomas Becket, Santiago de Compostela y la Virgen María. El culto de San Martín se hizo prominente en la Península Ibérica antes y después de la aparición del culto a Santiago de Compostela. En los sermones voluminosos de San Vicente Ferrer esta uno en Catalán que está dedicado a este santo tan venerado de Galia. Las fuentes más importantes procedentes de la antigu.edad tardía y principios medievales que forma el fondo de este sermón son Gallus y la Vita Sancti Martini de Sulpicio Severo. Sin embargo, en la alta edad media, su culto se popularizó a través de la Legenda Aurea escrita por el dominico

Frauen mit Eßstörungen im Ausdauersport

OpenAIRE

Bös, Annette

2003-01-01

Die vorliegende Arbeit untersucht das Phänomen Eßstörungen bei Ausdauersportlerinnen. Auf dem Hintergrund des identitätstheoretischen Ansatzes von Stahr et al. (1995) geht es um die Frage nach den Hauptverursachungsmomenten der Eßstörungen von sieben jungen Sportlerinnen. Im Rahmen einer qualitativen Sozialforschungsarbeit wurden sieben Athletinnen in einem problemzentrierten Interview zur Phase ihrer Eßstörungserkrankung befragt. Die Arbeit setzt sich zum Ziel, einen Beitrag zur systematisch...

POTENSI BIJI DAN EKSTRAK BIJI TERATAI (Nymphaea pubescens Willd SEBAGAI PENCEGAH DIARE PADA TIKUS PERCOBAAN YANG DIINTERVENSI E.coli ENTEROPATOGENIK

Directory of Open Access Journals (Sweden)

Yuspihana Fitrial

2013-03-01

Full Text Available The Potency of Waterlily’s Seed (Nymphaea pubescens Willd and Its Extract as DiarrheaPreventative in Rats that Intervented with Enterophatogenic Escherichia coli Yuspihana Fitrial, Made Astawan, Soewarno T.Soekarto,Komang G.Wiryawan, Tutik Wresdiyati ABSTRAK Penelitian ini bertujuan untuk mengetahui komponen Þ tokimia yang terdapat pada biji teratai dan ekstrak etil asetat bijiteratai dan mengetahui aktivitas antibakterinya terhadap E.coli penyebab diare (E.coli Enteropatogenik K1.1, EPECK1.1 pada tikus percobaan. Perlakuan diberikan pada tikus jantan jenis Sprague Dawley (berat 140 ±5 g selama28 hari. Tikus percobaan dibagi menjadi 4 grup yaitu, grup 1, kontrol (mendapatkan ransum standar, grup 2 yangmendapat ransum yang disubstitusi tepung biji teratai (18,7 g/100 g, grup 3 yang mendapat ransum yang disubstitusiFOS (fruktooligosakarida, 6 g/100 g, dan grup 4 yang mendapat ransum standar dan ekstrak etil asetat biji teratai(17,8 mg/ml. Setelah 2 minggu perlakuan ransum, tikus percobaan diintervensi secara oral dengan 0,3 ml dari 106CFU/ml EPEC K1.1 selama 1 minggu sehingga diare. Aktivitas biologis ransum perlakuan diamati dengan mengamatibobot badan, konsumsi ransum per hari, eÞ siensi ransum, total mikroba, total E.coli dan total bakteri asam laktatdari isi sekum tikus percobaan. Hasil penelitian menunjukkan bahwa biji teratai mengandung alkaloid, ß avonoid,steroid, glikosida, tanin, saponin, dan triterpenoid, sedangkan ekstrak etil asetat biji teratai mengandung alkaloid,ß avonoid, tanin, glikosida, saponin dan triterpenoid. Substitusi biji teratai pada ransum mampu menurunkan totalE.coli isi sekum, baik setelah intervensi maupun setelah intervensi EPEC dihentikan. Sementara pemberian ekstrakbiji teratai mampu menurunkan total E.coli isi sekum setelah intervensi dihentikan. EÞ siensi ransum pada grup yangdisubstitusi biji teratai lebih tinggi dibandingkan kontrol dan ekstrak biji teratai (P<0.05. Perlakuan substitusi bijiteratai, dan

Kirjallisuuskatsaus tiimityöstä

OpenAIRE

Uimi, Jutta

2012-01-01

Laurea-ammattikorkeakoulu Tiivistelmä Laurea Lohja Hoitotyön koulutusohjelma Uimi Jutta Kirjallisuuskatsaus tiimityöstä Vuosi 2012 Sivumäärä 43 Tämän opinnäytetyön tavoitteena oli kuvata kirjallisuuskatsauksen muodossa, miten tiimityö määritellään terveydenhuollon organisaatiossa ja tiimityön käytettävyyttä sekä millaisissa yhteyksissä tiimityötä käytetään. Tarkoituksena oli tuottaa tutkittua tietoa tiimityöstä Helsingin ja Uudenmaan sairaanhoitopiiriin (HUS) kuulu...

ST-segment resolution with bivalirudin versus heparin and routine glycoprotein IIb/IIIa inhibitors started in the ambulance in ST-segment elevation myocardial infarction patients transported for primary percutaneous coronary intervention: The EUROMAX ST-segment resolution substudy.

Science.gov (United States)

Van't Hof, Arnoud; Giannini, Francesco; Ten Berg, Jurrien; Tolsma, Rudolf; Clemmensen, Peter; Bernstein, Debra; Coste, Pierre; Goldstein, Patrick; Zeymer, Uwe; Hamm, Christian; Deliargyris, Efthymios; Steg, Philippe G

2017-08-01

Myocardial reperfusion after primary percutaneous coronary intervention (PCI) can be assessed by the extent of post-procedural ST-segment resolution. The European Ambulance Acute Coronary Syndrome Angiography (EUROMAX) trial compared pre-hospital bivalirudin and pre-hospital heparin or enoxaparin with or without GPIIb/IIIa inhibitors (GPIs) in primary PCI. This nested substudy was performed in centres routinely using pre-hospital GPI in order to compare the impact of randomized treatments on ST-resolution after primary PCI. Residual cumulative ST-segment deviation on the single one hour post-procedure electrocardiogram (ECG) was assessed by an independent core laboratory and was the primary endpoint. It was calculated that 762 evaluable patients were needed to show non-inferiority (85% power, alpha 2.5%) between randomized treatments. A total of 871 participated with electrocardiographic data available in 824 patients (95%). Residual ST-segment deviation one hour after PCI was 3.8±4.9 mm versus 3.9±5.2 mm for bivalirudin and heparin+GPI, respectively ( p=0.0019 for non-inferiority). Overall, there were no differences between randomized treatments in any measures of ST-segment resolution either before or after the index procedure. Pre-hospital treatment with bivalirudin is non-inferior to pre-hospital heparin + GPI with regard to residual ST-segment deviation or ST-segment resolution, reflecting comparable myocardial reperfusion with the two strategies.

St. Sofia in Ohrid, space, structure, forms: Sources

Directory of Open Access Journals (Sweden)

Korać Vojislav

2008-01-01

Full Text Available This work comments in particular on studies dealing with the church of St. Sofia in Ohrid. Among them are the monographs of two authors, Barbara Maria Schellewald (Die Arhitektur der Sophien Kirchen in Ohrid, Bon 1986 and Boris Čipan (Sveta Sofija, katedralen hram na ohridskata arhiepiskopija, Skopje 1995. Special attention is devoted to the typological interpretation of St. Sofia, to its initial design as a triple-nave basilica with a dome at the centre. Insightful descriptions are given about the older monuments in the Byzantine capital, Constantinople. Special attention is paid to the external architectonic workmanship. The western façade of St. Sofia demonstrates the features of Late Byzantine architecture, while the eastern façade directly reveals the triple-nave spatial design. That is why this article on St. Sofia contains sketches of the western and the eastern façades, illustrating the features of its architectonic specificities. On the whole, the author presents St. Sofia in Ohrid as a unique work of architecture of the Byzantine region. .

The 21st Century as Whose Century?

Directory of Open Access Journals (Sweden)

David Scott

2015-08-01

Full Text Available Macro-analysis and East-West encounter are shown through consideration of objective yet subjective constructed concepts for the international system and international economy in the 21st century. Three paradigms are considered, namely the 21st century as the ‘Pacific Century’, as ‘China’s Century’ and as the ‘Asian Century’. Overlaps are shown between these three paradigms, as also developments in time, and gradually shift in geographical location. The ‘Pacific Century’, and its associated Rimspeak, was the paradigm emerging in the late 1970s, knitting together America’s West Coast and the Japanese economy. By the late 1980s this was already shifting to talk of the 21st century likely to be an ‘Asian Century’ model, mark-1, based on the Pacific Asia dynamism shown by the ‘Asian Tigers’ and Japan. However, the Asian financial crash of 1997-8, and the economic downturn in Japan, meant that such an ‘Asian Century’ seemed premature as the 21st century arrived. Instead, it was China’s economic growth that seemed most evident, and with it the concept of the 21st century as ‘China’s Century’. However, in turn that has already been modified during the first decade of the century by India’s arrival as a rapidly growing economy. Consequently the 21st century as ‘China’s Century’ and as ‘India’s Century’ has been combined into talk of an ‘Asian Century’, mark-2.

St Sava and the cloud-chasers

OpenAIRE

Loma Aleksandar

2013-01-01

A gloss in the Nomocanon of St Sava condemns folk superstitions related to magically provoking hailstorms and eclipses. St Sava’s miracle with the king of Hungary as described in his Vitae seems to go back to the same complex of popular beliefs. Its acceptance by the hagiography was probably due to the influence of the figure of prince magician as common to the Serbian and the Russian oral epics.

St. Augustine in Twentieth-Century Music

DEFF Research Database (Denmark)

Petersen, Nils Holger

2012-01-01

A discussion - in a cultural historical perspective - of primarily two important twentieth-century musical works setting texts by St Augustine: Klaus Huber's Soliloquia Sancti Aurelii Augustini and Michael Tippett's The Vision of Saint Augustine.......A discussion - in a cultural historical perspective - of primarily two important twentieth-century musical works setting texts by St Augustine: Klaus Huber's Soliloquia Sancti Aurelii Augustini and Michael Tippett's The Vision of Saint Augustine....

The nutritional quality of herbaceous legumes on goats: Intake, digestibility and nitrogen balances

Directory of Open Access Journals (Sweden)

Simon P Ginting

2005-12-01

Full Text Available The availability of forages is a critical factor that determine the sustainability of the animal-plantation production system. In this typical production system, cover crops could be an important sources of forages to support the animal production. The study is aimed to evaluate the nutritional quality (chemical compositions, intake, digestibility and N balances of herbaceous legumes namely Arachis pintoi and Arachis glabrata having potential for used as alternative cover crops in plantation. Centerocema pubescens, a conventional cover crops used in plantation, was used as control. Twenty-one mature male goats (16-18 kg were used in this experiment. The animals were put in individual metabolism cages, divided into three groups (7 animal per group based on the body weight, and were randomly allocated into one of the three forages. The experiment was run in a Completely Randomized Design. The animals were allocated to an adaptation period for 14 days, followed by intake measurement for 5 days and fecal and urine collection for the next 7 days. During the fecal and urine collection forages were offered at 90% of the maximum intake. Chemical analyses showed that the DM and OM contents were relatively equal among the forages, but the crude protein content of C. pubescens (23.56% are relatively higher than those of A. pintoi (16.94% or of A. glabrata (15.19% The fiber (NDF content was also relatively higher in C. pubescens (59.37% than in A. pintoi (16.94% or A. glabrata (41.50%. The forage intake was highest (P0.05 between goats fed A. pintoi (466 g/d or A. glabrata (453 g/d. A similar trend was seen when intake was expressed as % BW (3.80, 3.50 and 3.40, respectively or as g/kg BW0.75 (42.4, 39.5 and 38.4, respectively. The digestion coeficient of DM (81.3% or OM (83.5% were highest (P0.05 between A. glabrata (71.9 and 73.2%, respectively and C. pubescens (73.7 and 74.2%, respectively. The trends were the same with the digestion coeficient of ADF

Henkilöstötilinpäätös Yritys Oy

OpenAIRE

Turunen, Tytti

2011-01-01

Tämän opinnäytetyön aiheena oli Yritys Oy:n henkilöstötilinpäätös vuodelta 2009. Henkilöstötilinpäätös jaetaan kahteen osaan, henkilöstötuloslaskelmaan ja henkilöstökertomukseen. Tavoitteena oli laatia Yritys Oy:lle henkilöstötilinpäätöksestä malli, jota yritys voi käyttää ja hyödyntää tulevaisuudessa henkilöstötilinpäätöstä laatiessa. Tavoitteena oli myös antaa kehittämisehdotuksia, minkälaista tietoa kannattaa kerätä seuraavia henkilöstötilinpäätöksiä varten. Henkilöstötilinpäätöksen tavoit...

21st Century Skills Map: World Languages

Science.gov (United States)

Partnership for 21st Century Skills, 2011

2011-01-01

This 21st Century Skills Map is the result of hundreds of hours of research, development and feedback from educators and business leaders across the nation. The Partnership for 21st Century Skills has issued this map for the core subject of World Languages. [Funding for this paper was provided by EF Education.

Clinically Relevant ESBL-Producing K. pneumoniae ST307 and E. coli ST38 in an Urban West African Rat Population

Directory of Open Access Journals (Sweden)

Katharina Schaufler

2018-02-01

Full Text Available High-risk ESBL-producing Enterobacteriaceae (ESBL-E have been described in wild birds and rodents worldwide. Rats are of special interest not only due to their indicator role for environmental pollution with multi-resistant bacteria but also as possible infection source. Data on the presence of high-risk ESBL-E in urban wildlife from Africa remain scarce, however. Twenty-nine animals from three different rat (Rattus species were captured in the city of Conakry (Guinea, West Africa in 2015. Rectal swabs were analyzed for ESBL-E using selective media. Species typing and phenotypic antimicrobial resistance analysis to broad-spectrum beta-lactams and other classes of antimicrobials was performed for Enterobacteriaceae-like isolates using the VITEK®2 system (BioMérieux, Germany. Confirmed ESBL-producing E. coli and K. pneumoniae were whole-genome sequenced and resistance genes, phylogenetic background and genes related to bacterial fitness and virulence were analyzed. In total, six of twenty-nine rats (20% carried ESBL-E (K. pneumoniae and E. coli. All ESBL-producers were multi-drug resistant with blaCTX−M−15 as the dominating ESBL-type. Interestingly, ESBL-associated clonal lineages E. coli ST38 and K. pneumoniae ST307 were found. The ESBL-plasmid in K. pneumoniae ST307 revealed high sequence similarities to pKPN3-307_TypeC, a >200 kbp IncFII plasmid originating from a human clinical ST307 isolate. This was in contrast to the core genome: the rat isolate was distantly related to the human clinical ST307 isolate (27 SNPs/Mbp. In addition, we identified π-fimbrial, capsule 2, and glycogen synthesis clusters in the rodent ST307 isolate, whose involvement in the adaptation to survival outside the host and in human urinary tracts has been suggested. Our results demonstrate the presence of clinically relevant, ESBL-producing K. pneumoniae ST307 and E. coli ST38 clonal lineages in an urban West African rat population. The human community is likely

St Sava and the cloud-chasers

Directory of Open Access Journals (Sweden)

Loma Aleksandar

2013-01-01

Full Text Available A gloss in the Nomocanon of St Sava condemns folk superstitions related to magically provoking hailstorms and eclipses. St Sava’s miracle with the king of Hungary as described in his Vitae seems to go back to the same complex of popular beliefs. Its acceptance by the hagiography was probably due to the influence of the figure of prince magician as common to the Serbian and the Russian oral epics.

Manufacturing and Design Engineering Students St. Mary's Hospital, Phoenix Park.

OpenAIRE

Mitchell, Leah

2012-01-01

Poster with details of project to improve ease of movement for Kirton Stirling chairs in St. Mary's Hospital, Phoenix Park, Dublin. Third year students in the B Eng (Honours) Manufacturing and Design Engineering course at Bolton St. completed a project in conjunction with St. Mary‟s Hospital, Phoenix Park. The staff in St Mary‟s were experiencing difficulty in moving the Kirton Stirling chairs (pictured above). These chairs are used to transport elderly patients from one location to another. ...

Multidimensional Space-Time Methodology for Development of Planetary and Space Sciences, S-T Data Management and S-T Computational Tomography

Science.gov (United States)

Andonov, Zdravko

This R&D represent innovative multidimensional 6D-N(6n)D Space-Time (S-T) Methodology, 6D-6nD Coordinate Systems, 6D Equations, new 6D strategy and technology for development of Planetary Space Sciences, S-T Data Management and S-T Computational To-mography. . . The Methodology is actual for brain new RS Microwaves' Satellites and Compu-tational Tomography Systems development, aimed to defense sustainable Earth, Moon, & Sun System evolution. Especially, extremely important are innovations for monitoring and protec-tion of strategic threelateral system H-OH-H2O Hydrogen, Hydroxyl and Water), correspond-ing to RS VHRS (Very High Resolution Systems) of 1.420-1.657-22.089GHz microwaves. . . One of the Greatest Paradox and Challenge of World Science is the "transformation" of J. L. Lagrange 4D Space-Time (S-T) System to H. Minkovski 4D S-T System (O-X,Y,Z,icT) for Einstein's "Theory of Relativity". As a global result: -In contemporary Advanced Space Sciences there is not real adequate 4D-6D Space-Time Coordinate System and 6D Advanced Cosmos Strategy & Methodology for Multidimensional and Multitemporal Space-Time Data Management and Tomography. . . That's one of the top actual S-T Problems. Simple and optimal nD S-T Methodology discovery is extremely important for all Universities' Space Sci-ences' Education Programs, for advances in space research and especially -for all young Space Scientists R&D!... The top ten 21-Century Challenges ahead of Planetary and Space Sciences, Space Data Management and Computational Space Tomography, important for successfully de-velopment of Young Scientist Generations, are following: 1. R&D of W. R. Hamilton General Idea for transformation all Space Sciences to Time Sciences, beginning with 6D Eukonal for 6D anisotropic mediums & velocities. Development of IERS Earth & Space Systems (VLBI; LLR; GPS; SLR; DORIS Etc.) for Planetary-Space Data Management & Computational Planetary & Space Tomography. 2. R&D of S. W. Hawking Paradigm for 2D

The significance of early post-exercise ST segment normalization.

Science.gov (United States)

Chow, Rudy; Fordyce, Christopher B; Gao, Min; Chan, Sammy; Gin, Kenneth; Bennett, Matthew

2015-01-01

The persistence of ST segment depression in recovery signifies a strongly positive exercise treadmill test (ETT). However, it is unclear if early recovery of ST segments portends a similar prognosis. We sought to determine if persistence of ST depression into recovery correlates with ischemic burden based on myocardial perfusion imaging (MPI). This was a retrospective analysis of 853 consecutive patients referred for exercise MPI at a tertiary academic center over a 24-month period. Patients were stratified into three groups based on the results of the ETT: normal (negative ETT), persistence (positive ETT with >1mm ST segment depression at 1minute in recovery) and early normalization (positive ETT with normalization, while 105 patients met criteria for persistence. The persistence group had a significantly greater SSS (8.48±7.77) than both the early normalization (4.34±4.98, pnormal (4.47±5.31, pnormalization and normal groups were not statistically different and met the prespecified non-inferiority margin (mean difference 0.12, -0.66=lower 95% CI, pnormal and 7.4% of early normalization groups. Among patients with an electrically positive ETT, recovery of ST segment depression within 1minute was associated with a lower SSS than patients with persistence of ST depression beyond 1minute. Furthermore, early ST segment recovery conferred a similar SSS to patients with a negative ETT. These results suggest that among patients evaluated for chest pain with a positive ETT, early recovery of the ST segment during recovery is associated with a significantly less ischemic burden on subsequent MPI and thus may represent a false positive finding in exercise treadmill testing. Copyright © 2015 Elsevier Inc. All rights reserved.

Serum soluble ST2 is associated with ER-positive breast cancer

International Nuclear Information System (INIS)

Lu, Da-peng; Zhou, Xiang-yu; Yao, Lu-tian; Liu, Cai-gang; Ma, Wei; Jin, Feng; Wu, Yun-fei

2014-01-01

ST2, a member of the interleukin (IL)-1receptor family, regulates Th1/Th2 immune responses in autoimmune and inflammatory conditions. However, the role of ST2 signaling in tumor growth and metastasis of breast cancers has not been investigated. This study investigated the possible role of soluble ST2 (sST2) in breast cancer. The serum levels of IL-33, sST2, and vascular endothelial growth factor (VEGF) in 150 breast cancer patients and 90 healthy women were measured by enzyme-linked immunosorbent assay. Estrogen receptor(ER), progesterone receptor, human epithelial receptor (HER)-2, and cell cycle regulated protein Ki-67 were measured. Clinical stage, tumor size, lymph node metastasis, and histological type were also recorded. The serum levels of sST2, IL-33, and VEGF were significantly higher in breast cancer patients than in the control group (P < 0.05, each). Serum sST2 levels in ER-positive breast cancer patients were significantly associated with age, histological type, clinical stage, tumor size, and Ki-67 status (P < 0.05, each). Moreover, the serum levels of IL-33 and sST2 in breast cancers significantly correlated with VEGF levels (IL-33: r = 0.375, P < 0.0001; sST2: r = 0.164, P = 0.045). Serum levels of sST2, IL-33, and VEGF decreased after modified radical mastectomy in ER-positive breast cancers. Serum levels of IL-33, sST2, and VEGF and clinicopathological factors were not significantly correlated with disease-free survival and overall survival of ER-positive breast cancer women during follow-up. Serum sST2 levels in ER-positive breast cancer patients are significantly associated with factors that indicate poor prognosis

78 FR 22416 - Amendment of Class E Airspace; St. Helena, CA

Science.gov (United States)

2013-04-16

... more above the surface of the earth. * * * * * AWP CA E5 St. Helena, CA [Amended] Napa County Fire... the name of the heliport listed in the Class E airspace for St. Helena, CA. St. Helena Fire Department Heliport has been changed to Napa County Fire Department Heliport, St. Helena, CA. This action does not...

Environmental Assessment on the leasing of the Strategic Petroleum Reserve, St. James Terminal, St. James Parish, Louisiana

International Nuclear Information System (INIS)

1995-01-01

The US Department of Energy (DOE) proposes to lease the Strategic Petroleum Reserve's (SPR) St. James Terminal to private industry. The St. James Terminal consists of six storage tanks, a pumping station, two maine docks and ancillary facilities. DOE believes that the St. James Terminal presents an opportunity to establish a government- industry arrangement that could more effectively use this asset to serve the nations's oil distribution needs, reduce the operational cost of the SPR, and provide a source of revenue for the Government. DOE solicited interest in leasing its distribution facilities in a notice published March 16, 1994. In response, industry has expressed interest in leasing the St. James Terminal, as well as several DOE pipelines, to enhance the operation of its own facilities or to avoid having to construct new ones. Under such a lease, industry use would be subordinate to DOE use in the event of a national energy emergency. This Environmental Assessment describes the proposed leasing operation, its alternatives, and potential environmental impacts. Based on this analyses, DOE has determined that the proposed action is not a major Federal action significantly affecting the quality of the human environment within the meaning of the National Environmental Policy Act (NEPA) OF 1969 and has issued the Finding of No Significant Impact (FONSI)

Danmarks Største Fossiler

DEFF Research Database (Denmark)

Lindow, Bent Erik Kramer; Cuny, Gilles Guy Roger

2008-01-01

For 8 millioner år siden myldrede Nordsøen af en mangfoldighed af hajer, hvaler, havskildpadder og sæler, mange flere end i dag. Blandt dem finder man Danmarks største fossiler som er udstillet på Museum Sønderjylland - Naturhistorie og Palæontologi i Gram.......For 8 millioner år siden myldrede Nordsøen af en mangfoldighed af hajer, hvaler, havskildpadder og sæler, mange flere end i dag. Blandt dem finder man Danmarks største fossiler som er udstillet på Museum Sønderjylland - Naturhistorie og Palæontologi i Gram....

Diagnostics of ST Plasmas in NSTX: Challenges and Opportunities

International Nuclear Information System (INIS)

Johnson, D.; Efthimion, P.; Foley, J.; Jones, B.; Mazzucato, E.; Park, H.; Taylor, G.; Levinton, F.; Luhmann, N.

2001-01-01

This paper will highlight some of the challenges and opportunities present in the diagnosis of spherical torus (ST) plasmas on the National Spherical Torus Experiment (NSTX) and discuss the corresponding diagnostic development that is presently underway. After a brief description of diagnostic systems currently installed, examples of ST-specific diagnostic challenges will be highlighted, as will another case, where the ST configuration offers opportunities for new measurements

Detection of ST772 Panton-Valentine leukocidin-positive methicillin-resistant Staphylococcus aureus (Bengal Bay clone and ST22 S. aureus isolates with a genetic variant of elastin binding protein in Nepal

Directory of Open Access Journals (Sweden)

R.H. Pokhrel

2016-05-01

Full Text Available Genetic characteristics were analysed for recent clinical isolates of methicillin-resistant and -susceptible Staphylococcus aureus (MRSA and MSSA respectively in Kathmandu, Nepal. MRSA isolates harbouring Panton-Valentine leukocidin (PVL genes were classified into ST1, ST22 and ST88 with SCCmec-IV and ST772 with SCCmec-V (Bengal Bay clone, while PVL-positive MSSA into ST22, ST30 and ST772. ST22 isolates (PVL-positive MRSA and MSSA, PVL-negative MRSA possessed a variant of elastin binding protein gene (ebpS with an internal deletion of 180 bp, which was similar to that reported for ST121 S. aureus previously outside Nepal. Phylogenetic analysis indicated that the ebpS variant in ST22 might have occurred independently of ST121 strains. This is the first report of ST772 PVL-positive MRSA in Nepal and detection of the deletion variant of ebpS in ST22 S. aureus.

ST Safety What's on?

CERN Document Server

Jacot, C

2001-01-01

Du premier coup de pioche jusqu'à la mise en place de la tente abritant le buffet offert lors de la cérémonie d'achèvement d'un projet, la division ST est sur les rangs et apporte son savoir faire. Ces projets nombreux et pluridisciplinaires sont étudiés, se réalisent, s'exploitent et font l'objet de maintenance jusqu'à leur démantèlement. Durant leurs cycles de vie, la division ST avance les compétences professionnelles spécifiques à chaque corps de métiers incluant le recours à de nombreux contrats avec des entreprises extérieures pour réaliser les travaux sur les sites du CERN. Pour en conserver la maîtrise, la division ST applique une gestion de projet, une assurance de la qualité et s'attache tout particulièrement à la sécurité, à la réglementation, à la prévention des risques et la gestion de ceux-ci. Sous la supervision du DSO, un ensemble de procédures et de démarches a été développé afin de faciliter les tâches du maître d'ouvrage et des entreprises contractantes, c...

Simulation of ground-water flow in the St. Peter aquifer in an area contaminated by coal-tar derivatives, St. Louis Park, Minnesota. Water Resources Investigation

International Nuclear Information System (INIS)

Lorenz, D.L.; Stark, J.R.

1990-01-01

A model constructed to simulate ground-water flow in part of the Prairie du Chien-Jordan and St. Peter aquifers, St. Louis Park, Minnesota, was used to test hypotheses about the movement of ground water contaminated with coal-tar derivatives and to simulate alternatives for reducing the downgradient movement of contamination in the St. Peter aquifer. The model, constructed for a previous study, was applied to simulate the effects of current ground-water withdrawals on the potentiometric surface of the St. Peter aquifer. Model simulations predict that the multiaquifer wells have the potential to limit downgradient migration of contaminants in the St. Peter aquifer caused by cones of depression created around the multiaquifer wells. Differences in vertical leakage to the St. Peter aquifer may exist in areas of bedrock valleys. Model simulations indicate that these differences are not likely to affect significantly the general patterns of ground-water flow

Moving towards first science with the St. George recoil separator

Science.gov (United States)

Meisel, Zachary; Berg, G. P. A.; Gilardy, G.; Moran, M.; Schmitt, J.; Seymour, C.; Stech, E.; Couder, M.

2015-10-01

The St. George recoil mass separator has recently been coupled to the 5MV St. Ana accelerator at the University of Notre Dame's Nuclear Science Lab. St. George is a unique tool designed to measure radiative alpha-capture reactions for nuclei up to A = 40 in inverse kinematics in order to directly obtain cross sections required for astrophysical models of stellar and explosive helium burning. Commissioning of St. George is presently taking place with primary beams of hydrogen, helium, and oxygen. In this presentation, results will be shown for the measured energy acceptance of St. George, which compare favorably to COSY results when employing the calculated optimal ion-optical settings. Additionally, future plans will be discussed, such as assessing the angular acceptance of St. George and the re-integration of HiPPO at the separator target position to provide a dense, windowless helium gas-jet target. The material presented in this work is partially supported by the National Science Foundation Grant No. 1419765.

St. Bernard Parish : la crise d’un territoire suburbain St. Bernard Parish, the crisis of a suburban territory

Directory of Open Access Journals (Sweden)

Jean-Marc Zaninetti

2009-04-01

Full Text Available Situé à l’est de La Nouvelle-Orléans, St. Bernard Parish est l’un des territoires les plus vulnérables au risque d’ondes de tempêtes de toute la région métropolitaine. Après avoir été ravagée par le cyclone Katrina en 2005, St. Bernard peine à se redresser et montre le plus faible niveau de reprise de toute la région du Golfe du Mexique frappée par Katrina. De plus, la reconstruction est freinée par des polémiques virulentes qui nous rappellent les pires années des tensions raciales des années 1960. Cet article s’intéresse aux relations supposées entre les fragmentations urbaines et la faculté d’adaptation aux risques naturels. L’étude du cas de St. Bernard illustre la force d’inertie des territoires et comment de vieilles querelles ville-banlieue affaiblissent la résilience urbaine.Located east of New Orleans, St. Bernard Parish is one of the most vulnerable parts of the greater New Orleans metropolitan area to storm surges. After having been devastated by Hurricane Katrina in 2005, St. Bernard still struggles to recover from the storm, and displays the lowest recovery level of the entire Katrina-hit Gulf Coast area so far. Moreover, reconstruction is hampered by loud polemics that remind us of the worst years of racial polarization during the 1960’s. This paper explores the possible linkage between urban fragmentations and adaptive capacity to natural hazard. The St. Bernard case-study illustrates the strength of path dependency, and how long-entrenched suburb-central city mistrust hampers urban resilience.

Materials for the 21st century

CERN Document Server

Segal, David

2017-01-01

The book is a general text that shows how materials can contribute to solving problems facing nations in the 21st century. It is illustrated with diverse applications and highlights the potential of existing materials for everyday life, healthcare and the economies of nations. There are 13 chapters and a glossary of 500 materials with their descriptions, historical development, their use or potential use and a range of references. Specific areas include synthetic polymers (e.g. nylon), natural polymers (e.g. proteins, cellulose) and the role of materials in the development of digital computers and in healthcare. Solid-state lighting, energy supplies in the 21st century, disruptive technologies and intellectual property, in particular patents, are discussed. The book concludes by asking how the 21st century will be characterised. Will it be the Silicon Age, Genomic Age or New Polymer Age, as examples?

Analyse of Maintenance Cost in ST

CERN Document Server

Jenssen, B W

2001-01-01

An analyse has been carried out in ST concerning the total costs for the division. Even though the target was the maintenance costs in ST, the global budget over has been analysed. This has been done since there is close relation between investments & consolidation and the required level for maintenance. The purpose of the analyse was to focus on maintenance cost in ST as a ratio of total maintenance costs over the replacement value of the equipment, and to make some comparisons with other industries and laboratories. Families of equipment have been defined and their corresponding ratios calculated. This first approach gives us some "quantitative" measurements. This analyse should be combined with performance indicators (more "qualitative" measurements) that are telling us how well we are performing. This will help us in defending our budget, make better priorities, and we will satisfy the requirements from our external auditors.

Modelos matemáticos para estimar el crecimiento del fruto de chile manzano (Capsicum pubescens R y P

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P. C. Rojas-Lara

2008-01-01

Full Text Available El híbrido intervarietal de chile manzano (Capsicum pubescens R y P Puebla x Zongolica es de alto rendimiento por su volumen, grosor de pericarpio y peso de fruto. El rendimiento se explica principalmente por el tamaño del fruto, siendo recomendable conocer la dinámica del crecimiento del mismo. Normalmente su análisis se realiza por medio de muestreos destructivos, lo que hace imposible utilizar el mismo fruto durante el ciclo de cultivo, además la competencia entre los órganos de la planta disminuye su tamaño y peso, afectando negativamente la calidad y rendimiento. Por lo cual el estudio del crecimiento a través de modelos matemáticos utilizando variables no destructivas permite proponer un manejo adecuado del cultivo. Por esta razón se propuso evaluar e identificar modelos matemáticos que describan el crecimiento del fruto, sin realizar muestreos destructivos. Se evaluaron los modelos: regresión lineal simple, regresión lineal múltiple y cuatro modelos no lineales. Con la hipótesis de que alguno de los seis modelos estudiados, explica eficientemente dicho crecimiento por medio de la variable independiente volumen de agua desplazada. Las plantas de chile se cultivaron bajo un sistema de producción intensivo, en 2004 y 2005. La variable dependiente fue el peso fresco de fruto y las variables independientes fueron: tiempo de crecimiento del fruto, longitud, ancho promedio de los hombros del fruto, volumen de agua desplazada y volumen del mismo. Se encontraron diferencias significativas entre las medias de las variables evaluadas en los dos periodos de muestreo (P<0.05. Los modelos que mejor explican el crecimiento del fruto son: regresión lineal simple (sólo en el 2004 en función del volumen de agua desplazada y el volumen de fruto, el modelo de regresión lineal múltiple describe adecuadamente dicho crecimiento utilizando además de las variables anteriormente mencionadas, el tiempo de crecimiento, la longitud y el ancho

St. Croix trap study

Data.gov (United States)

National Oceanic and Atmospheric Administration, Department of Commerce — The data set contains detailed information about the catch from 600 trap stations around St. Croix. Data fields include species caught, size data, trap location...

Church of St. Peter and Paul in the village under Kopaonik

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Raičević Slobodan

2009-01-01

Full Text Available In the border of the municipality towards Kosovo, Kuršumlija preserved the St. Cemetery's church of Peter and Paul in village Lukovo near the famous rehabilitation center Lukovo's spa. Church is one nave with a semicircular apse at the east vaults with semicircular arch reinforced with cross sec­tion curve, which relies on a few strong pilasters placed inside long walls. According to folk tradition the church was built in the middle ages and served to diggers and foundries of lead ores of King Milutin. Upon termination of exploitation ore the church neglected and in the 19th century it suffered its first renewal 1871st and another 1895th year. Saved epigraphic inscription with carved year of renewal (1895th, icons and wall decor of the church provide information about reliably judging its recent history and artistic value. Soon after the bricklaying work 1895th Church has received from the altar wall of icons, and after that, and mural painting small artistic value. The crown of the vault is painted Pantocrator, about whose performances are painted scenes of the Transfiguration, Ascension of Christ, Vavedenje and Entry into Jerusalem. On the western wall are shown the Dormition of the Mother of God and in the first zone are shown standing figures of Sts. Constantine and Helena, St. Simon Mir refills and St. Prince Lazar - kefaloforos. On the triumphal arch are Old. Testament scenes of hospitality and sacrifice of Abraham and in the apse bust of God Savaot. In the zone of standing figures are shown Sts. Druid, St. Czar Uroš and St. King Stephen, St. Sunday, St. Petka, St. Procopius, and St. George. From the figures standing at the altar of bishops are shown St. John Chrysostom, St. Sava Serbian, St. Basil the Great and St. Athanasius. There was saved the altar compartments with icons. At the czar's gate are shown Blagovesti and in the order of main icons: Christ Almighty, Mother of God with Christ, St. John the Forerunner, icons of patron St

Principal Component Surface (2011) for St. Thomas East End Reserve, St. Thomas

Data.gov (United States)

National Oceanic and Atmospheric Administration, Department of Commerce — This image represents a 0.3x0.3 meter principal component analysis (PCA) surface for areas the St. Thomas East End Reserve (STEER) in the U.S. Virgin Islands (USVI)....

Clinical significance of stress-induced ST segment changes in patients with previous myocardial infarction

International Nuclear Information System (INIS)

Futagami, Yasuo; Hamada, Masayuki; Makino, Katsutoshi; Ichikawa, Takehiko; Konishi, Tokuji

1984-01-01

To explain the clinical significance of stress(st)-induced ST-segment (ST) changes postinfarction, 93 patients with previous myocardial infarction (MI) were performed st- 201 Tl myocardial single photon emission computed tomography (SPECT) and compared ST changes with SPECT, coronary arteriographic and left ventriculographic findings. 30 out of 93 cases (32%) had ST depression, 20 (21.5%) had ST elevation, 9 (10%) had both ST depression and elevation and remaining 34 (36.5 %) had no significant ST changes. In single vessel disease, ST depression were noted in 29% (12/42), while in multivessel disease, 53% (27/51). 35 out of 39 cases (90%) with ST depression had transient perfusion defect but no apparent relation was noted between location of ST depression on ECG and region of transient perfusion defect in SPECT. All of 28 cases with ST elevation were noted in anterior MI cases, and 26 out of these showed severe LV wall motion abnormality in contrast left ventriculography and broad anterior permanent defect in SPECT. Only 15 cases (54%) showed slight redistribution. Thus, we conclude that in patients with previous MI, st-induced ST depression seems to reflect myocardial ischemia and ST elevation possibly related abnormal LV wall motion. (author)

In vitro placental self and cross pollination in some species

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Azza Shehata

2014-01-01

Full Text Available Excised placentae with ovules of Primula pubescens, P. auricula, Scopolia carniolica, Digitalis purpurea, Torenia fournieri and Chionodoxa luciliae were self pollinated in vitro and the development of seeds was observed. The same method was used for obtaining hybrid globular embryos from crosses between: P. pubescens x P. auricula, Scopolia carniolica x Physochlaina praealta, Melandrium album x Silene saxifraga and M. album x Arenaria pungens.

ST-segment depression in aVR as a predictor of culprit artery in acute inferior wall ST-segment elevation myocardial infarction

Directory of Open Access Journals (Sweden)

Ahmed Hafez el-neklawy

2014-03-01

Conclusions: ST depression in aVR is common in patients with LCX-related acute inferior myocardial infarction. The ST changes in this lead are associated with an excellent specificity and a good sensitivity in differentiating LCX from RCA as the IRA.

At stå i det åbne

DEFF Research Database (Denmark)

Hansen, Finn Thorbjørn

Bogen At stå i det åbne: Dannelse gennem filosofisk undren og nævær er en pædagogisk-filosofisk undersøgelse af, hvad det vil sige at stå i et "undringsfællesskab" i en undervisnings- og vejledningssituation. Ved at trække på den eksistentiel-fænomenologiske og filosofisk-hermeneutiske forskning ...

Three centuries of multi-storied St. Petersburg

Science.gov (United States)

Lavrov, Leonid; Perov, Fedor; Eremeeva, Aleksandra; Temnov, Vladimir

2018-03-01

The article is devoted to assessment of the role of high-rise buildings in the St. Petersburg historic city's ensemble. Features of formation of city architectural look, the conditions of city typical silhouette's appearance which is characterized by the contrast of a small number of high-rise structures with a low horizontal mass building are observed. The consequences of the emergence of a significant number of great height buildings, the silhouette of which conflicts with the traditional St. Petersburg landscape's compositional principles, are analyzed. The economic reasons of high-rise construction of residential and office buildings are given. The conclusions about the prospects of St. Petersburg high-rise construction in the light of city-building and economic factors are made.

Orthodoxy and Islam. St. Cyril and St. Gregory Palamas in Dialogue with Muslims

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Grzegorz Makal

2014-12-01

Full Text Available The purpose of this study is to present the role of the Holy Fathers in the dialogue between the Orthodox and theMuslims. The first part of the article talks about the mission of St. Cyril in Baghdad Caliphate in historical perspective. Itdeals with his dialogue with Islam and presents an analysis of the arguments used by both sides. In the second part I talkabout the dialogue of St. Gregory Palamas with Muslims in the context of the mission of Cyril, comparing the argumentsof both fathers and their attitudes towards the dialogue with Islam. Finally, the theory of the “biblical roots of Europe” isaddressed, drawing on the example of the abovementioned Holy Fathers. In the article some excerpts from Palamas’worksare published in Polish for the first time.

Increased serum concentrations of soluble ST2 predict mortality after burn injury.

Science.gov (United States)

Hacker, Stefan; Dieplinger, Benjamin; Werba, Gregor; Nickl, Stefanie; Roth, Georg A; Krenn, Claus G; Mueller, Thomas; Ankersmit, Hendrik J; Haider, Thomas

2018-06-27

Large burn injuries induce a systemic response in affected patients. Soluble ST2 (sST2) acts as a decoy receptor for interleukin-33 (IL-33) and has immunosuppressive effects. sST2 has been described previously as a prognostic serum marker. Our aim was to evaluate serum concentrations of sST2 and IL-33 after thermal injury and elucidate whether sST2 is associated with mortality in these patients. We included 32 burn patients (total body surface area [TBSA] >10%) admitted to our burn intensive care unit and compared them to eight healthy probands. Serum concentrations of sST2 and IL-33 were measured serially using an enzyme-linked immunosorbent assay (ELISA) technique. The mean TBSA was 32.5%±19.6%. Six patients (18.8%) died during the hospital stay. Serum analyses showed significantly increased concentrations of sST2 and reduced concentrations of IL-33 in burn patients compared to healthy controls. In our study cohort, higher serum concentrations of sST2 were a strong independent predictor of mortality. Burn injuries cause an increment of sST2 serum concentrations with a concomitant reduction of IL-33. Higher concentrations of sST2 are associated with increased in-hospital mortality in burn patients.

Characterization of StABF1, a stress-responsive bZIP transcription factor from Solanum tuberosum L. that is phosphorylated by StCDPK2 in vitro.

Science.gov (United States)

Muñiz García, María Noelia; Giammaria, Verónica; Grandellis, Carolina; Téllez-Iñón, María Teresa; Ulloa, Rita María; Capiati, Daniela Andrea

2012-04-01

ABF/AREB bZIP transcription factors mediate plant abiotic stress responses by regulating the expression of stress-related genes. These proteins bind to the abscisic acid (ABA)-responsive element (ABRE), which is the major cis-acting regulatory sequence in ABA-dependent gene expression. In an effort to understand the molecular mechanisms of abiotic stress resistance in cultivated potato (Solanum tuberosum L.), we have cloned and characterized an ABF/AREB-like transcription factor from potato, named StABF1. The predicted protein shares 45-57% identity with A. thaliana ABFs proteins and 96% identity with the S. lycopersicum SlAREB1 and presents all of the distinctive features of ABF/AREB transcription factors. Furthermore, StABF1 is able to bind to the ABRE in vitro. StABF1 gene is induced in response to ABA, drought, salt stress and cold, suggesting that it might be a key regulator of ABA-dependent stress signaling pathways in cultivated potato. StABF1 is phosphorylated in response to ABA and salt stress in a calcium-dependent manner, and we have identified a potato CDPK isoform (StCDPK2) that phosphorylates StABF1 in vitro. Interestingly, StABF1 expression is increased during tuber development and by tuber-inducing conditions (high sucrose/nitrogen ratio) in leaves. We also found that StABF1 calcium-dependent phosphorylation is stimulated by tuber-inducing conditions and inhibited by gibberellic acid, which inhibits tuberization.

Environmental Assessment on the leasing of the Strategic Petroleum Reserve, St. James Terminal, St. James Parish, Louisiana

Energy Technology Data Exchange (ETDEWEB)

NONE

1995-01-01

The US Department of Energy (DOE) proposes to lease the Strategic Petroleum Reserve`s (SPR) St. James Terminal to private industry. The St. James Terminal consists of six storage tanks, a pumping station, two maine docks and ancillary facilities. DOE believes that the St. James Terminal presents an opportunity to establish a government- industry arrangement that could more effectively use this asset to serve the nations`s oil distribution needs, reduce the operational cost of the SPR, and provide a source of revenue for the Government. DOE solicited interest in leasing its distribution facilities in a notice published March 16, 1994. In response, industry has expressed interest in leasing the St. James Terminal, as well as several DOE pipelines, to enhance the operation of its own facilities or to avoid having to construct new ones. Under such a lease, industry use would be subordinate to DOE use in the event of a national energy emergency. This Environmental Assessment describes the proposed leasing operation, its alternatives, and potential environmental impacts. Based on this analyses, DOE has determined that the proposed action is not a major Federal action significantly affecting the quality of the human environment within the meaning of the National Environmental Policy Act (NEPA) OF 1969 and has issued the Finding of No Significant Impact (FONSI).

Contrasting short-term performance of mountain birch (Betula pubescens ssp. czerepanovii treeline along a latitudinal continentality-maritimity gradient in the southern Swedish Scandes

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Lisa Öberg

2012-01-01

Full Text Available Positional treeline shift is a fundamental aspect and indicator of high-mountain vegetation response to climate change. This study analyses treeline performance during the period 2005/2007 -2010/2011 in the Swedish Scandes. Focus is on mountain birch (Betula pubescens ssp. czerepanovii along a regional climatic maritimity-continentality gradient. Treeline upshift by 3.0 yr-1 in the maritime part differed significantly from retreat by 0.4 m yr-1 in the continental part of the transect. This discrepancy is discussed in terms of differential warming-induced snow cover phenology patterns and their influence on soil moisture conditions. In the continental area, earlier and more complete melting of prior relatively rare late-lying snow patches, even high above the treeline, has progressed to a state when melt water irrigation ceases. As a consequence, soil drought sets back the vigor of existing birches and precludes sexual regeneration and upslope advance of the treeline. In the maritime area, extensive and deep snow packs still exist above the treeline and constrain its position, although some release is taking place in the current warm climate. Thereby, the birch treeline expands upslope as the alpine snow patches shrink, but continue to provide sufficient melt water throughout the summer. Treeline rise appears to have been based primarily on seed regeneration over the past few decades. This is a novelty, since prior (1915-2007 treeline advance was accomplished mainly by in situ shifts in growth form of relict krummholz birches, in some cases millennial-old, prevailing above the treeline. By the snow phenology mechanism, birch can benefit from climate warming in the maritime region, which contrasts with the situation in the continental region. This discrepancy should be accounted for in projective models. In a hypothetical case of sustained warming, the subalpine birch forest belt may expand less extensively than often assumed, although advance may

Carl Størmer Auroral Pioneer

CERN Document Server

Egeland, Alv

2013-01-01

This biography summarizes the seminal contributions to auroral and space science of Carl Størmer (1874 - 1957). He was the first to develop precise photographic methods to calculate heights and morphologies of diverse auroral forms during four solar cycles. Størmer independently devised numerical techniques to determine the trajectories of high-energy charged particles allowed and forbidden in the Earth’s magnetic field. His theoretical analyses explained cosmic ray access to the upper atmosphere, 20 years before they were identified by other scientists. Størmer’s crowning achievement, “The Polar Aurora,” published when he was 81 years old, stands to this day as a regularly cited guide in graduate-level courses on space physics.   The authors present the life of this prodigious scientist in relation to the cultural life of early 20th century in Norway and to the development of the space sciences in the post-Sputnik era.

Using ichthyotoxic plants as bioinsecticide: A literature review

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J. N. ANDRADE

2015-12-01

Full Text Available ABSTRACTSome ichthyotoxic plants are study object aiming to discover promising substances in the field of Biotechnology, in search of plant extracts which can be used or even transformed into natural insecticides. This paper presents a bibliographical survey in order to check the traditional use of ichthyotoxic plants as bioinsecticide. Among the plants identified as ichthyotoxic, the most cited in traditional use are those from the genera Derris, Serjania, Lonchocarpus, Magonia, and Tephrosia. The survey suggests that ichthyotoxic plant extracts can contain classes of chemical compounds such as isoflavonoids and tannins with a bioinsecticidal effect and, thus, they can be used in Biotechnology, contributing to reduce the use of synthetic insecticides that present a high toxicity level.

GeoTIFF of 3x3 m Bathymetry for St. Thomas & St. John, 2011, UTM 20N NAD83 (NCEI Accession 0131858)

Data.gov (United States)

National Oceanic and Atmospheric Administration, Department of Commerce — This image represents a LiDAR (Light Detection & Ranging) 3x3 meter resolution bathymetric surface for an area of shallow seabed surrounding St. Thomas and St....

21st Century leadership skills for learning networks

NARCIS (Netherlands)

Basten, Floor; Evers, Arnoud; Geijsel, Femke; Vermeulen, Marjan

2018-01-01

Ultimate goal: to prepare pupils for a life in a society that requires 21st century skills and actions Immediate focus: teachers and principals develop 21st century skills in the practice of their work → together with researchers principals co-create tools to support teacher learning.

St. Louis encephalitis virus possibly transmitted through blood transfusion-Arizona, 2015.

Science.gov (United States)

Venkat, Heather; Adams, Laura; Sunenshine, Rebecca; Krow-Lucal, Elisabeth; Levy, Craig; Kafenbaum, Tammy; Sylvester, Tammy; Smith, Kirk; Townsend, John; Dosmann, Melissa; Kamel, Hany; Patron, Roberto; Kuehnert, Matthew; Annambhotla, Pallavi; Basavaraju, Sridhar V; Rabe, Ingrid B

2017-12-01

St. Louis encephalitis virus is a mosquito-borne flavivirus that infrequently causes epidemic central nervous system infections. In the United States, blood donors are not screened for St. Louis encephalitis virus infection, and transmission through blood transfusion has not been reported. During September 2015, St. Louis encephalitis virus infection was confirmed in an Arizona kidney transplant recipient. An investigation was initiated to determine the infection source. The patient was interviewed, and medical records were reviewed. To determine the likelihood of mosquito-borne infection, mosquito surveillance data collected at patient and blood donor residences in timeframes consistent with their possible exposure periods were reviewed. To investigate other routes of exposure, organ and blood donor and recipient specimens were obtained and tested for evidence of St. Louis encephalitis virus infection. The patient presented with symptoms of central nervous system infection. Recent St. Louis encephalitis virus infection was serologically confirmed. The organ donor and three other organ recipients showed no laboratory or clinical evidence of St. Louis encephalitis virus infection. Among four donors of blood products received by the patient via transfusion, one donor had a serologically confirmed, recent St. Louis encephalitis virus infection. Exposure to an infected mosquito was unlikely based on the patient's minimal outdoor exposure. In addition, no St. Louis encephalitis virus-infected mosquito pools were identified around the patient's residence. This investigation provides evidence of the first reported possible case of St. Louis encephalitis virus transmission through blood product transfusion. Health care providers and public health professionals should maintain heightened awareness for St. Louis encephalitis virus transmission through blood transfusion in settings where outbreaks are identified. © 2017 AABB.

Fusion power core engineering for the ARIES-ST power plant

International Nuclear Information System (INIS)

Tillack, M.S.; Wang, X.R.; Pulsifer, J.; Malang, S.; Sze, D.K.; Billone, M.; Sviatoslavsky, I.

2003-01-01

ARIES-ST is a 1000 MWe fusion power plant based on a low aspect ratio 'spherical torus' (ST) plasma. The ARIES-ST power core was designed to accommodate the unique features of an ST power plant, to meet the top-level requirements of an attractive fusion energy source, and to minimize extrapolation from the fusion technology database under development throughout the world. The result is an advanced helium-cooled ferritic steel blanket with flowing PbLi breeder and tungsten plasma-interactive components. Design improvements, such as the use of SiC inserts in the blanket to extend the outlet coolant temperature range were explored and the results are reported here. In the final design point, the power and particle loads found in ARIES-ST are relatively similar to other advanced tokamak power plants (e.g. ARIES-RS [Fusion Eng. Des. 38 (1997) 3; Fusion Eng. Des. 38 (1997) 87]) such that exotic technologies were not required in order to satisfy all of the design criteria. Najmabadi and the ARIES Team [Fusion Eng. Des. (this issue)] provide an overview of ARIES-ST design. In this article, the details of the power core design are presented together with analysis of the thermal-hydraulic, thermomechanical and materials behavior of in-vessel components. Detailed engineering analysis of ARIES-ST TF and PF systems, nuclear analysis, and safety are given in the companion papers

Molecular evidence for the thriving of Campylobacter jejuni ST-4526 in Japan.

Directory of Open Access Journals (Sweden)

Hiroshi Asakura

Full Text Available Campylobacter jejuni is a leading cause of human gastroenteritis worldwide. This study aimed at a better understanding of the genetic diversity of this pathogen disseminated in Japan. We performed multilocus sequence typing (MLST of Campylobacter jejuni isolated from different sources (100 human, 61 poultry, and 51 cattle isolates in Japan between 2005 and 2006. This approach identified 62 sequence types (STs and 19 clonal complexes (CCs, including 11 novel STs. These 62 STs were phylogenetically divided into 6 clusters, partially exhibiting host association. We identified a novel ST (ST-4526 that has never been reported in other countries; a phylogenetic analysis showed that ST-4526 and related STs showed distant lineage from the founder ST, ST-21 within CC-21. Comparative genome analysis was performed to investigate which properties could be responsible for the successful dissemination of ST-4526 in Japan. Results revealed that three representative ST-4526 isolates contained a putative island comprising the region from Cj0737 to Cj0744, which differed between the ST-4526 isolates and the reference strain NCTC11168 (ST-43/CC-21. Amino acid sequence alignment analyses showed that two of three ST-4526 isolates expressed 693aa- filamentous hemagglutination domain protein (FHA, while most of other C. jejuni strains whose genome were sequenced exhibited its truncation. Correspondingly, host cell binding of FHA-positive C. jejuni was greater than that of FHA-truncated strains, and exogenous administration of rFHA protein reduced cell adhesion of FHA-positive bacteria. Biochemical assays showed that this putative protein exhibited a dose-dependent binding affinity to heparan sulfate, indicating its adhesin activity. Moreover, ST-4526 showed increased antibiotic-resistance (nalidixic acid and fluoroquinolones and a reduced ability for DNA uptake. Taken together, our data suggested that these combined features contributed to the clonal thriving of ST

CDC WONDER: Population - Bridged-Race July 1st Estimates

Data.gov (United States)

U.S. Department of Health & Human Services — The Population - Bridged-Race July 1st Estimates online databases report bridged-race population estimates of the July 1st resident population of the United States,...

Perinnöstä luopuminen

OpenAIRE

Skoutti, Miia

2013-01-01

Tämän opinnäytetyön keskeisenä aiheena oli tutkia perinnöstä luopumiseen liittyviä edellytyksiä ja seurauksia. Tarkoituksena oli käsitellä perinnöstä luopumista erilaisista näkökulmista sekä miettiä joitakin siihen johtavia syitä. Opinnäytetyöhön sisältyy olennaisesti myös yleisesti perintöoikeudellisten asioiden selvittäminen. Opinnäytetyön alussa lukijalle selitetään lyhyesti sitä, mitä on lakimääräinen perimysjärjestys, ja miten perintöä voi Suomessa saada. Lisäksi huomiota kiinnitetään lu...

Omsorg/støtte i ungdomsskolen

OpenAIRE

Vasseng, Eli Dahl

2012-01-01

Master's thesis in Special education Denne studien handler om forholdet mellom lærer-elev og ser på hvordan ungdomsskoleelever beskriver omsorgsfulle/støttende lærere og den betydning det har for motivasjon i skolearbeid og læringsmiljø. Jeg har tatt utgangspunkt i ungdomsskoleelevenes forståelse av fenomenet omsorg/støtte og brukt en fenomenologisk tilnærming med intervju som metode. Seks elever fra ungdomstrinnet ble intervjuet og jeg har brukt en intervjuguide som er bygget på det teore...

Statistics in the 21st century

CERN Document Server

Wells, Martin T; Wells, Martin T

2001-01-01

Exactly what is the state of the art in statistics as we move forward into the 21st century? What promises, what trends does its future hold? Through the reflections of 70 of the world's leading statistical methodologists, researchers, theorists, and practitioners, Statistics in the 21st Century answers those questions. Originally published in the Journal of the American Statistical Association, this collection of vignettes examines our statistical past, comments on our present, and speculates on our future. Although the coverage is broad and the topics diverse, it reveals the essential intell

Energirenovering af større bygninger

DEFF Research Database (Denmark)

Mortensen, Lone Hedegaard; Birck Laustsen, Jacob; Vorre, Mette Havgaard

involverede parter i et renoveringsprojekt om, hvordan energirenoveringsprojekter gennemføres i alle faser. SBi-anvisning 269 kan bruges som styringsredskab for bygherrer og kravgrundlag for rådgivere, entreprenører og andre parter, der leverer ydelser til bygherren. For institutioner, der stiller kapital til......​SBi-anvisning 269 omhandler metode og proces for gennemførelse af energirenoveringsprojekter for større bygninger fra idefase til driftsfase. Større bygninger omfatter etageboliger, bygninger til privat handel- og service samt offentlige institutioner. Anvisningen giver vejledning for de...

31st Annual conference and the 21st annual theoretical seminar of the South African Institute of Physics

International Nuclear Information System (INIS)

1986-01-01

The 31st annual conference and the 21st annual theoretical seminar of the South African Institute of Physics was held from 7-11 July 1986 at the Rand Afrikaans University, Johannesburg. This publication contains only the abstracts of seminars delivered on the conference. The topics that were covered include the various facets of physics such as solid state physics, nuclear and particle physics, optics and spectroscopy, solar-terrestrial physics, education, and applied and industrial physics

Book of specifications (StLB) and solar technology in data processing

Energy Technology Data Exchange (ETDEWEB)

Jaehnig, W; Schiemann, W

1982-06-01

The book of specifications (StLB) is to create a common language for a system of integrated data processing in building construction to be used by all those participating in the process of construction. The StLB comprises e.g. special sectors from the field of framework construction and extension as well as of technical extension. Special performance sectors concerning solar energy are not yet included in the StLB. It can be expected that relevant texts for solar technology shall be included along with other editorial work. At present, analogous texts from various performance sectors can be transferred to solar technology. Different user programmes are available for the data-related utilization of the StLlB. The article illustrates the fields of application of the StLB and its data-related utilization procedure including text input as well as the various devices which are suitable for the individual processes of the StLB.

High water availability increases the negative impact of a native hemiparasite on its non-native host.

Science.gov (United States)

Cirocco, Robert M; Facelli, José M; Watling, Jennifer R

2016-03-01

Environmental factors alter the impacts of parasitic plants on their hosts. However, there have been no controlled studies on how water availability modulates stem hemiparasites' effects on hosts. A glasshouse experiment was conducted to investigate the association between the Australian native stem hemiparasite Cassytha pubescens and the introduced host Ulex europaeus under high (HW) and low (LW) water supply. Cassytha pubescens had a significant, negative effect on the total biomass of U. europaeus, which was more severe in HW than LW. Regardless of watering treatment, infection significantly decreased shoot and root biomass, nodule biomass, nodule biomass per unit root biomass, F v/F m, and nitrogen concentration of U. europaeus. Host spine sodium concentration significantly increased in response to infection in LW but not HW conditions. Host water potential was significantly higher in HW than in LW, which may have allowed the parasite to maintain higher stomatal conductances in HW. In support of this, the δ(13)C of the parasite was significantly lower in HW than in LW (and significantly higher than the host). C. pubescens also had significantly higher F v/F m and 66% higher biomass per unit host in the HW compared with the LW treatment. The data suggest that the enhanced performance of C. pubescens in HW resulted in higher parasite growth rates and thus a larger demand for resources from the host, leading to poorer host performance in HW compared with LW. C. pubescens should more negatively affect U. europaeus growth under wet conditions rather than under dry conditions in the field. © The Author 2015. Published by Oxford University Press on behalf of the Society for Experimental Biology.

The mean, the median, and the St. Petersburg paradox.

Science.gov (United States)

Hayden, Benjamin Y; Platt, Michael L

2009-06-01

The St. Petersburg Paradox is a famous economic and philosophical puzzle that has generated numerous conflicting explanations. To shed empirical light on this phenomenon, we examined subjects' bids for one St. Petersburg gamble with a real monetary payment. We found that bids were typically lower than twice the smallest payoff, and thus much lower than is generally supposed. We also examined bids offered for several hypothetical variants of the St. Petersburg Paradox. We found that bids were weakly affected by truncating the gamble, were strongly affected by repeats of the gamble, and depended linearly on the initial "seed" value of the gamble. One explanation, which we call the median heuristic , strongly predicts these data. Subjects following this strategy evaluate a gamble as if they were taking the median rather than the mean of the payoff distribution. Finally, we argue that the distribution of outcomes embodied in the St. Petersburg paradox is so divergent from the Gaussian form that the statistical mean is a poor estimator of expected value, so that the expected value of the St. Petersburg gamble is undefined. These results suggest that this classic paradox has a straightforward explanation rooted in the use of a statistical heuristic.

Geology of St. John, U.S. Virgin Islands

Science.gov (United States)

Rankin, Douglas W.

2002-01-01

The rocks of St. John, which is located near the eastern end of the Greater Antilles and near the northeastern corner of the Caribbean plate, consist of Cretaceous basalt, andesite, keratophyre, their volcaniclastic and hypabyssal intrusive equivalents, and minor calcareous rocks and chert. These rocks were intruded by Tertiary mafic dikes and tonalitic plutons. The oldest rocks formed in an extensional oceanic environment characterized by abundant keratophyre and sheeted dikes. Subduction-related volcanism of the east-west-trending marine Greater Antilles volcanic arc began on St. John near the transition between the Early and Late Cretaceous. South-directed compression, probably caused by the initial collision between the Greater Antilles arc of the Caribbean plate and the Bahama platform of the North American plate, deformed the Cretaceous strata into east-west-trending folds with axial-plane cleavage. Late Eocene tonalitic intrusions, part of the Greater Antilles arc magmatism, produced a contact aureole that is as much as two kilometers wide and that partly annealed the axial-plane cleavage. East-west compression, possibly related to the relative eastward transport of the Caribbean plate in response to the beginning of spreading at the Cayman Trough, produced long-wavelength, low-amplitude folds whose axes plunge gently north and warp the earlier folds. A broad north-plunging syncline-anticline pair occupies most of St. John. The last tectonic event affecting St. John is recorded by a series of post-late Eocene sinistral strike-slip faults related to the early stages of spreading at the Cayman Trough spreading center and sinistral strike-slip accommodation near the northern border of the Caribbean plate. Central St. John is occupied by a rhomb horst bounded by two of these sinistral faults. Unlike other parts of the Greater Antilles, evidence for recent tectonic movement has not been observed on St. John.

Alternative Fuels Data Center: St. Louis Airport Relies on Biodiesel and

Science.gov (United States)

Natural Gas Vehicles St. Louis Airport Relies on Biodiesel and Natural Gas Vehicles to someone by E-mail Share Alternative Fuels Data Center: St. Louis Airport Relies on Biodiesel and Natural Gas Vehicles on Facebook Tweet about Alternative Fuels Data Center: St. Louis Airport Relies on Biodiesel and

Bovine-associated MRSA ST398 in The Netherlands

Directory of Open Access Journals (Sweden)

Tavakol Mehri

2012-05-01

Full Text Available Abstract During routinely screening (50.000 milk samples on an annual basis 14 MRSA ST398 strains were identified in the period of January 2008 to September 2008 in 14 different dairy herds located in the provinces Overijssel and Gelderland, The Netherlands. Molecular analysis was performed by Cfr9I PFGE, ST398-specific diagnostic PCR, spa typing, SCCmec typing and Panton-Valentine Leukocidin (PVL gene PCR. The molecular analyses of 14 MRSA (one MRSA strain per herd strains revealed that all strains belong to ST398 with 3 closely related spa types (t011, t108 and t889, all commonly found in pigs and carry 2 different SCCmec types, IVa and V. All MRSA strains were resistant to two or more classes of antibiotics and also PVL negative. The majority of farms (n = 9, 64% harboured combined livestock with both cows and pigs present. Our study contributes to the growing evidence that MRSA ST398 is transmitted among various animal species and can be considered as an etiological agent of mastitis in dairy cows.

Methylphenidatinduceret ST-elevations-myokardieinfarkt

DEFF Research Database (Denmark)

Ruwald, Martin Huth; Ruwald, Anne-Christine Huth; Tønder, Niels

2012-01-01

Adult attention deficit and hyperkinetic disorder (ADHD) is increasingly diagnosed and treated with methylphenidate. We present the case of an 20 year-old man, who was diagnosed with ADHD and suffered a ST elevation acute myocardial infarction due to coronary vasospasm related to an overdose...

Simple stålrammebygninger

DEFF Research Database (Denmark)

Ellum, J.C.

Anvisningen gennemgår dimensioneringen og bringer detaljerede konstruktionstegninger til simple stålrammebygninger, dvs. lukkede, fritliggende bygninger i én etage, hvor tagkonstruktionen ud over egenlast kun er påvirket af naturlaster, dvs. sne og vind. Dimensioneringen sker ved at udfylde et di...

Right bundle branch block and anterior wall ST elevation myocardial infarction.

Science.gov (United States)

Trofin, Monica; Israel, Carsten W; Barold, S Serge

2017-09-01

We report the case of an acute anterior wall ST elevation myocardial infarction with new left anterior fascicular block and pre-existing right bundle branch block. Due to a wide right bundle branch block, no ST segment elevation was visible in lead V1. The left anterior fascicular block was caused by proximal occlusion of the left artery descending and disappeared after acute revascularization. However, also the R' of the right bundle branch block became significantly shorter after revascularization, dismanteling a minor ST segment elevation. The ST elevation in lead V1 in anterior wall infarction and right bundle branch block may merge with the R' and cause a further QRS widening as an "equivalent" to the ST elevation.

MHD simulation of relaxation to a flipped ST configuration

Energy Technology Data Exchange (ETDEWEB)

Kagei, Y [Department of Electrical Engineering and Computer Sciences, Himeji Institute of Technology, Himeji, Hyogo (Japan); Nagata, M [Department of Electrical Engineering and Computer Sciences, Himeji Institute of Technology, Himeji, Hyogo (Japan); Suzuki, Y [Center for Promotion of Computational Science and Engineering, Japan Atomic Energy Research Institute, Taito-ku, Tokyo (Japan); Kishimoto, Y [Naka Fusion Research Establishment, Japan Atomic Energy Research Institute, Naka-machi, Ibaraki (Japan); Hayashi, T [National Institute for Fusion Science, Toki, Gifu (Japan); Uyama, T [Department of Electrical Engineering and Computer Sciences, Himeji Institute of Technology, Himeji, Hyogo (Japan)

2003-02-01

The dynamics of spherical torus (ST) plasmas, when the external toroidal magnetic field is decreased to zero and then increased in the opposite direction, has been investigated using three-dimensional magnetohydrodynamic (MHD) numerical simulations. It has been found that the flipped ST configuration is self-organized after the ST configuration collapses because of the growth of the n = 1 mode in the open flux region and a following magnetic reconnection event. During the transition between these configurations, not only the paramagnetic toroidal field but also the poloidal field reverses polarity spontaneously. (letter to the editor)

Bathymetry (2011) of the St. Thomas East End Reserve

Data.gov (United States)

National Oceanic and Atmospheric Administration, Department of Commerce — This image represents a LiDAR (Light Detection & Ranging) 0.3x0.3 meter resolution depth surface for the St. Thomas East End Reserve (STEER), St. Thomas in the...

Policy perspective on the global use of Smokeless Tobacco (ST: a literature review

Directory of Open Access Journals (Sweden)

Kamran Siddiqi

2018-03-01

gaps in the implementation of key demand-reduction measures with regard to ST. Methods A series of focused literature reviews was conducted and findings were synthesized by relevant Articles (6 - 14 of the World Health Organization Framework Convention on Tobacco Control (WHO FCTC. Results We found sufficient evidence to support implementation of key demand-reduction measures for ST. For example, raising taxes can reduce ST consumption, with price elasticity on a par with, or sometimes higher than, cigarettes. Similarly, graphic pictorial warnings on ST packaging are far more effective than text-only warning labels. But despite supportive evidence, countries have either not implemented measures or have kept the bar much lower than that for cigarettes. For example, very few countries regulate the contents of ST products. Some have raised ST taxes but not to the extent of cigarette taxes, risking product substitution. Similarly, health-warning requirements for ST are less strict than those for cigarettes. Even where strong policies exist, compliance has been poor. For example, despite bans on ST advertising, most suppliers continue to promote products, especially at points of sale and via print and digital media. Consequently, ST demand-reduction measures have had limited impact. Conclusions The full implementation of FCTC Articles 6-14 is likely to reduce the global demand for ST, but their current state of implementation lags behind that for cigarettes. The existing policy gaps can be addressed through better knowledge of ST products, setting unambiguous standards, innovative systems for tax administration, building capacity in testing ST products and undertaking targeted research.

ACTIVITATEA ANTIOXIDANTĂ A SUBSTANŢELOR DIN MUGURII ARBORILOR STEJARULUI PUFOS (QUERCUS PUBESCENS WILLD. CARE CRESC ÎN DIFERITE CONDIŢII STAŢIONALE

Directory of Open Access Journals (Sweden)

Gheorghe FLORENTA

2018-03-01

Full Text Available A fost determinată activitatea sumară a oxidazelor, catalazelor şi a substanţelor reducătoare a extractelor din mugurii stejarului pufos prelevaţi primăvara de la arborii care cresc în diferite condiţii staţionale din sudul Republicii Moldova. În extracte se manifesta clar tendinţa de sporire a capacităţii sumare de utilizare a oxigenului datorită potenţialului reductiv al substanţelor fenolice şi activităţii oxidazelor la arborii care cresc mai la sud, ceea ce corespunde gradientului de sporire a temperaturii primăvara în direcţia nord-sud. Această tendinţă s-a manifestat şi pentru activitatea catalazelor, dar mai puţin pronunţat. Primăvara, în celulele mugurilor apicali schimbările componentelor care determină potenţialul oxidoreductiv se manifestă mai timpuriu, în comparaţie cu cele din mugurii laterali. Această accelerare poate fi o cauză a eliminării mai timpurii a dormitării mugurilor apicali în comparaţie cu cei laterali.THE ANTIOXIDANT ACTIVITY OF PUBESCENT OAK TREE BUDS (QUERCUS PUBESCENS WILLD. WHICH GROW UNDER DIFFERENT STATIONARY CONDITIONSIt was determined the summary activity of oxidases, catalases and reducing substances of extracts from pubescent oak shoots taken in spring from trees growing in different stationary conditions in the southern part of the Republic of Moldova. In the extracts, the tendency to increase the overall capacity of oxygen use due to the reductive potential of the phenolic substances and the activity of the oxidases in trees growing southwards is clearly manifested, which corresponds to the gradient of increasing the spring temperature in the north-south direction. This trend also manifested itself in the catalase activity, but less pronounced. In apical buds, in spring, the changes in the components that determine the oxidoreductive potential are manifested earlier, compared to those in lateral buds. This acceleration may be a reason of the early removal of

Methicillin-resistant Staphylococcus aureus in Rio de Janeiro hospitals: dissemination of the USA400/ST1 and USA800/ST5 SCCmec type IV and USA100/ST5 SCCmec type II lineages in a public institution and polyclonal presence in a private one.

Science.gov (United States)

Caboclo, Roberta Mello Ferreira; Cavalcante, Fernanda Sampaio; Iorio, Natalia Lopes Pontes; Schuenck, Ricardo Pinto; Olendzki, André Nogueira; Felix, Maria José; Chamon, Raiane Cardoso; dos Santos, Kátia Regina Netto

2013-03-01

Methicillin-resistant Staphylococcus aureus (MRSA) infections have changed since certain non-multiresistant MRSA lineages have emerged in hospitals. In this study, 99 MRSA isolates, 77 from a public and 22 from a private hospital, were characterized. Isolates were tested for antimicrobial susceptibility, whereas staphylococcal chromosomal cassette mec (SCCmec) typing and Panton-Valentine leukocidin genes were assessed by polymerase chain reaction. Pulsed-field gel electrophoresis and multilocus sequence typing analyses were carried out to determine the MRSA lineages. High rates of resistance were found to erythromycin (96%), ciprofloxacin (93%), and clindamycin (90%). The SCCmec types found were as follows: type II (14.2%), III (62.6%), and IV (23.2%). Approximately 85% of type III isolates was related to the Brazilian epidemic clone in both hospitals. For type IV isolates, 94.4% were related to both USA400/ sequence type (ST) 1 and USA800/ST5 lineages in the public hospital, whereas the USA400/ST1, USA800/ST5, USA1100/ST30, and EMRSA (Epidemic MRSA)-15/ST22 lineages were detected in the private hospital. Among the SCCmec II isolates, approximately 85% were related to the USA100/ST5 lineage. Three MRSA isolates were positive to Panton-Valentine leukocidin genes. The study showed that there was an emergence of USA400/ST1, USA800/ST5 SCCmec IV, and USA100/ST5 SCCmec II MRSA lineages in both hospitals. There was a dissemination of them in the public hospital and a polyclonal presence of the MRSA isolates in the private hospital. The spread of these lineages can be facilitated by the characteristics of the health institution. Copyright © 2013 Association for Professionals in Infection Control and Epidemiology, Inc. Published by Mosby, Inc. All rights reserved.

Doppler derived gradient of ST Jude Mechanical Prosthesis, early postoperative assessment

International Nuclear Information System (INIS)

Shaikh, A.H.; Hanif, B.; Adil, A.; Hashimi, S.; Qazi, H.A.; Mujtaba, I.

2010-01-01

Objective: To determine the doppler derived mean gradients of St Jude mechanical prosthesis in early postoperative period in patients undergoing valve replacement at a tertiary care cardiac centre. Methods: Medical records of 190 consecutive patients who underwent 233 mitral, aortic or dual (mitral and aortic) valve replacement by St Jude bileaflet mechanical prosthesis at Tabba Heart Institute, between March 2006 to December 2008 were reviewed. Doppler derived mean gradients were assessed predischarge and recorded. Results: There were 98 (51.5%) males and 92 (48.5%) females in the study cohort. The mean age was 40 +- 14 years. Of the total, 101 (53%) had mitral, 46 (24.2%) had aortic and 43 (22.6%) patients had dual valve replacement. Doppler derived mean gradient was assessed across 144 mitral and 89 aortic St Jude mechanical prosthesis. Doppler derived mean gradient for St Jude mitral prosthesis was 3.5 mm Hg and for St Jude aortic prosthesis was 10.2 mm Hg. Conclusions: The study determines baseline gradients across mitral and aortic St Jude mechanical prosthesis in our population. These can be used as reference gradients to assess St Jude prosthetic valve function in patients who did not have early postoperative doppler assessment. (author)

Organ accumulation and subcellular location of Cicer arietinum ST1 protein.

Science.gov (United States)

Albornos, Lucía; Cabrera, Javier; Hernández-Nistal, Josefina; Martín, Ignacio; Labrador, Emilia; Dopico, Berta

2014-07-01

The ST (ShooT Specific) proteins are a new family of proteins characterized by a signal peptide, tandem repeats of 25/26 amino acids, and a domain of unknown function (DUF2775), whose presence is limited to a few families of dicotyledonous plants, mainly Fabaceae and Asteraceae. Their function remains unknown, although involvement in plant growth, fruit morphogenesis or in biotic and abiotic interactions have been suggested. This work is focused on ST1, a Cicer arietinum ST protein. We established the protein accumulation in different tissues and organs of chickpea seedlings and plants and its subcellular localization, which could indicate the possible function of ST1. The raising of specific antibodies against ST1 protein revealed that its accumulation in epicotyls and radicles was related to their elongation rate. Its pattern of tissue location in cotyledons during seed formation and early seed germination, as well as its localization in the perivascular fibres of epicotyls and radicles, indicated a possible involvement in seed germination and seedling growth. ST1 protein appears both inside the cell and in the cell wall. This double subcellular localization was found in every organ in which the ST1 protein was detected: seeds, cotyledons and seedling epicotyls and radicles. Copyright © 2014 Elsevier Ireland Ltd. All rights reserved.

Communication from ST Group

CERN Multimedia

TS Department

2008-01-01

In order to prepare the organization of the Open Days, please note that FM Group will not able to take into account either specific requests for waste collection from 2nd to 6th of April, either removal or PC transport requests between the 31st and the 11th of March. We kindly ask you to plan the collection of any type of waste and the urgent transport of office furniture or PC before the 31st of March. Waste collection requests shall be formulated contacting FM Support at 77777 or at the email address mailto:Fm.Support@cern.ch; removal of office furniture or PC transport requests must be made using the EDH ‘Transport request’ form selecting the "Removals" or the "PC transport" category from the drop-down menu. For any question concerning the waste sorting, please consult the following web address: http://dechets-waste.web.cern.ch/dechets-waste/. Thank you for your understanding and collaboration. TS/FM Group

Neutron flux distribution measurement in the Fort St. Vrain initial core (results of Fort St. Vrain start-up test A-7)

International Nuclear Information System (INIS)

Marshall, A.C.; Brown, J.R.

1975-01-01

A description is given of a test to measure the axial flux distribution at several radial locations in the Fort St. Vrain core representing unrodded, rodded, and partially rodded regions. The measurements were intended to verify the calculational accuracy of the three-dimensional calculational model used to compute axial power distributions for the Fort St. Vrain core. (U.S.)

Control Strategy Tool (CoST)

Data.gov (United States)

U.S. Environmental Protection Agency — The EPA Control Strategy Tool (CoST) is a software tool for projecting potential future control scenarios, their effects on emissions and estimated costs. This tool...

Genomic Epidemiology of Hypervirulent Serogroup W, ST-11 Neisseria meningitidis.

Science.gov (United States)

Mustapha, Mustapha M; Marsh, Jane W; Krauland, Mary G; Fernandez, Jorge O; de Lemos, Ana Paula S; Dunning Hotopp, Julie C; Wang, Xin; Mayer, Leonard W; Lawrence, Jeffrey G; Hiller, N Luisa; Harrison, Lee H

2015-10-01

Neisseria meningitidis is a leading bacterial cause of sepsis and meningitis globally with dynamic strain distribution over time. Beginning with an epidemic among Hajj pilgrims in 2000, serogroup W (W) sequence type (ST) 11 emerged as a leading cause of epidemic meningitis in the African 'meningitis belt' and endemic cases in South America, Europe, Middle East and China. Previous genotyping studies were unable to reliably discriminate sporadic W ST-11 strains in circulation since 1970 from the Hajj outbreak strain (Hajj clone). It is also unclear what proportion of more recent W ST-11 disease clusters are caused by direct descendants of the Hajj clone. Whole genome sequences of 270 meningococcal strains isolated from patients with invasive meningococcal disease globally from 1970 to 2013 were compared using whole genome phylogenetic and major antigen-encoding gene sequence analyses. We found that all W ST-11 strains were descendants of an ancestral strain that had undergone unique capsular switching events. The Hajj clone and its descendants were distinct from other W ST-11 strains in that they shared a common antigen gene profile and had undergone recombination involving virulence genes encoding factor H binding protein, nitric oxide reductase, and nitrite reductase. These data demonstrate that recent acquisition of a distinct antigen-encoding gene profile and variations in meningococcal virulence genes was associated with the emergence of the Hajj clone. Importantly, W ST-11 strains unrelated to the Hajj outbreak contribute a significant proportion of W ST-11 cases globally. This study helps illuminate genomic factors associated with meningococcal strain emergence and evolution.

Biometria de frutos e sementes e emergência de plântulas de duas espécies frutíferas do gênero Campomanesia Biometrics of fruits and seeds and seedling emergence of two species fruit of the Campomanesia genus

Directory of Open Access Journals (Sweden)

Michele Camargo de Oliveira

2011-06-01

Full Text Available As espécies Campomanesia adamantium e Campomanesia pubescens são morfologicamente semelhantes, ocorrem em ambientes comuns do Bioma Cerrado, por isso são difíceis de serem separadas e identificadas. Os objetivos foram analisar dados biométricos de frutos e sementes de C. adamantium e de C. pubescens, além do processo de emergência das plântulas, para fins de comparações entre as espécies. Em novembro de 2007, de 50 frutos de cada espécie, foram realizadas medidas do comprimento transversal (mm e longitudinal (mm dos frutos e das sementes, massa da matéria fresca dos frutos (g, número de lóculos por fruto e número de lóculos com sementes. Para o teste de emergência, dois experimentos independentes, um para cada espécie, foram instalados em delineamento inteiramente casualizado, com seis métodos de beneficiamento dos frutos para remoção, secagem ou lavagem da mucilagem e quatro repetições com 40 sementes por parcela. Com frutos mais volumosos, com maior acúmulo de massa fresca e maior amplitude biométrica em relação aos de C. pubescens, C. adamantium apresenta potencial para seleção de materiais promissores para fins de melhoramento. A secagem à sombra por 24 horas das sementes com mucilagem reduz os percentuais de emergência e de plântulas normais, além da velocidade de emergência de plântulas de C. adamantium, embora este método seja indiferente para plântulas de C. pubescens. Sob as mesmas condições experimentais, plântulas de C. pubescens apresentam maior capacidade de emergência e de plântulas normais, além de maiores frequências diárias de plântulas emersas e redução dos tempos de emergência em relação às plântulas de C. adamantium.The species Campomanesia adamantium and Campomanesiapubescens are morphologically similar, occur in common areas in the Cerrado, so they are difficult to be separated and identified. The objectives were to analyze biometrics of fruits and seeds of C. adamantium

The Changing Pattern of Population Structure of Staphylococcus aureus from Bacteremia in China from 2013 to 2016: ST239-030-MRSA Replaced by ST59-t437.

Science.gov (United States)

Li, Shuguang; Sun, Shijun; Yang, Chentao; Chen, Hongbin; Yin, Yuyao; Li, Henan; Zhao, Chunjiang; Wang, Hui

2018-01-01

To investigate the epidemiology and genetic structure of Staphylococcus aureus bacteremia in China, a total of 416 isolates from 22 teaching hospitals in 12 cities from 2013 and 2016 were characterized by antibiogram analysis, multilocus sequence typing (MLST), spa typing and staphylococcal cassette chromosome mec (SCC mec ) typing. The predominant meticillin-susceptible (MSSA) genotypes in 2013 were ST188 (19.1%), ST7 (8.7%), and ST398 (7.8%), respectively, and they continued to be the main genotypes in 2016. The prevalence of meticillin-resistant S. aureus (MRSA) were 36.5% (66/181) and 36.6% (86/235) in 2013 and 2016, respectively. Interestingly, the susceptibility rates of MRSA to rifampicin and fluoroquinolones increased significantly from 2013 to 2016 ( P competition and fitness measurements were performed. Importantly, ST239-t030-MRSA displayed lower growth rate and lower competitive advantage compared to ST59-t437-MRSA. Together, our findings reveal that fitness advantage of ST59-t437-MRSA over ST239-t030-MRSA may lead to changes in genetic structure and increased susceptibility of MRSA to rifampicin and fluoroquinolones in Chinese patients with S. aureus bacteremia. Our study supports temporal dynamics in MRSA clone diversities, further providing critical insights into the importance of continued monitoring of MRSA.

Housing Service: Receptions of the CERN and St.-Genis-Pouilly Hostels

CERN Multimedia

2005-01-01

Opening times Please note the new and definitive opening times of the Receptions of the hostels on the Swiss site of CERN and in St. Genis : CERN hostels St.-Genis hostel from Monday to Friday 7:30 - 19:30 8:00 - 12:00 16:00 - 19:00 Saturday 9:00 - 13:00 closed Sunday 9:00 - 13:00 closed Outside these times keys to rooms reserved in advance can be obtained from the guards on duty at the main entrance to the Meyrin, Switzerland, CERN site (Gate B), where they are deposited some fifteen minutes after the closure of the Reception. As for the St. Genis hostel, for arrivals on Saturdays and Sundays, the keys are deposited with the guards in advance on the preceding Friday evening. Reminder : reservations, whether for the CERN hostels or the St. Genis hostel, are available through the Reception of the CERN hostels. Once the reservation has been confirmed, in the case of St. Genis, all other business, including payment, is dealt with by the St. Genis hostel reception. As far as possible, all r...

Exercise induced ST elevation and residual myocardial ischemia in previous myocardial infarction

International Nuclear Information System (INIS)

Shimonagata, Tsuyoshi; Nishimura, Tsunehiko; Uehara, Toshiisa; Hayashida, Kohei; Saito, Muneyasu; Sumiyoshi, Tetsuya

1987-01-01

The purpose of this study was to evaluate the clinical significance of stress induced ST elevation on infarcted area in 65 patients with previous myocardial infarction (single vessel disease) who had stress thallium scan. Stress induced ST changes on infarcted area were compared with quantitative assessment of myocardial ischemia (thallium ischemic score; TIS) and extent of myocardial infarction (defect score; DS) derived from circumferential profile analysis. In patients with previous myocardial infarction in less than 3 month from the onset (n = 36), left ventricular ejection fraction (LVEF) and extent of abnormal LV wall motion were not significantly different between patients with stress induced ST elevation ( ≥ 2 mm, n = 26) and those with stress induced ST elevation ( < 2 mm, n = 10), while, in patients with previous myocardial infarction in more than 3 month (n = 29), patients with stress induced ST elevation ( ≥ 2 mm, n = 15) showed left ventricular dyskinesis more frequently than those with ST elevation ( < 2 mm, n = 14). In addition, the former showed significantly higher DS and significantly lower TIS than the latter. In patients with previous myocardial infarction in less than 3 month, patients with ST elevation ( ≥ 2 mm, n = 15) with prominent upright T wave (n = 15) had transient thallium defect in infarcted area in 73 % and they had significantly higher LVEF and TIS than those with ST elevation ( < 2 mm, n = 11). These results indicated that ST elevation in infarcted area reflect different significance according to the recovery of injured myocardium and stress induced ST elevation with prominent upright T wave in infarcted area reflect residual myocardial ischemia in less than 3 month from the onset of myocardial infarction. (author)

The First Outbreak Caused by Acinetobacter baumannii ST208 and ST195 in China

Directory of Open Access Journals (Sweden)

Junyan Qu

2016-01-01

Full Text Available This study aimed to analyze the clinical characteristics of patients and molecular mechanisms of the first outbreak mainly caused by sequence types (STs 208 multidrug resistant (MDR Acinetobacter baumannii in China. A total of 10 clinical samples were collected from 5 patients who were involved in the outbreak. Bacterial identification and antibiotic sensitivity tests were performed by the VITEK-2 COMPACT automated system. MICs of tigecycline for clinical isolates were determined using broth microdilution. The clonal relatedness of A. baumannii clinical isolates in our local settings was determinated by pulsed-field gel electrophoresis (PFGE and multilocus sequence typing (MLST. A total of 7 A. baumannii strains were isolated and all were MDR strains; two of them were carbapenem-nonsusceptible strains. blaOXA-23 was the only acquired carbapenemase gene in the isolates. The isolates belonged to a single clonal pulsotype determined by PFGE and two sequences types (STs determined by MLST. The isolates belonged to the globally disseminated clonal complex 92, among which ST195 and ST208 were the most common sequence types (71.43% and 28.57%. The outbreak was successfully controlled by stringent infection control measures, especially improving the hand hygiene compliance and enhancing antimicrobial stewardship. In conclusion, this is the first description of an outbreak caused mainly by A. baumannii of ST208 in China. Infection control measures should be strengthened when infection outbreaks in hospital.

Henkilöstöjohtamisella vaikutusta työhyvinvointiin : Henkilöstöjohtamisen käsikirja tukena esimiestyön haasteissa

OpenAIRE

Viitasaari, Tuomas

2014-01-01

Yhteiskunnallisesti katsottuna työhyvinvointi on tärkeässä asemassa. Hyvällä johtamisella voidaan vaikuttaa työhyvinvointiin ja sen parantamiseen. Tässä opinnäytetyössä tutkitaan käytännön henkilöstöjohtamista ja henkilöstöjohtamisen käsikirjan merkitystä esimiestyössä. Opinnäytteeni ensimmäisenä tavoitteena on vastata siihen, mikä on hyvää henkilöstöjohtamista ja miten sitä voidaan tukea. Toinen tavoite on työpaikkani SPR Kontti kierrätystavarataloketjun toimeksiannon mukaisesti tutkia henki...

St. Anselm and Teaching

Science.gov (United States)

Evans, Gillian R.

1976-01-01

Discusses the educational principles and methods of the medieval philosopher and theologian, St. Anselm. Educational practices of medieval monastic schools, town schools, private tutors, and pastoral teaching are discussed. Available from: Taylor & Francis Ltd., P.O. Box 9137, Church Street Station, New York, N.Y. 10049. (Author/DB)

Using SDI-12 with ST microelectronics MCU's

Energy Technology Data Exchange (ETDEWEB)

Saari, Alexandra [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Hinzey, Shawn Adrian [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Frigo, Janette Rose [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Proicou, Michael Chris [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Borges, Louis [Los Alamos National Lab. (LANL), Los Alamos, NM (United States)

2015-09-03

ST Microelectronics microcontrollers and processors are readily available, capable and economical processors. Unfortunately they lack a broad user base like similar offerings from Texas Instrument, Atmel, or Microchip. All of these devices could be useful in economical devices for remote sensing applications used with environmental sensing. With the increased need for environmental studies, and limited budgets, flexibility in hardware is very important. To that end, and in an effort to increase open support of ST devices, I am sharing my teams' experience in interfacing a common environmental sensor communication protocol (SDI-12) with ST devices.

Methicillin-Resistant Staphylococcus aureus ST398 from Human Patients, Upper Austria

Science.gov (United States)

Metz-Gercek, Sigrid; Mittermayer, Helmut

2009-01-01

Methicillin-resistant Staphylococcus aureus (MRSA) clonal type ST398 is usually associated with animals. We examined 1,098 confirmed MRSA samples from human patients and found that 21 were MRSA ST398. Most (16) patients were farmers. Increasing prevalence from 1.3% (2006) to 2.5% (2008) shows emergence of MRSA ST398 in humans in Austria. PMID:19402964

The mean, the median, and the St. Petersburg paradox

Directory of Open Access Journals (Sweden)

Benjamin Y. Hayden

2009-06-01

Full Text Available The St.~Petersburg Paradox is a famous economic and philosophical puzzle that has generated numerous conflicting explanations. To shed empirical light on this phenomenon, we examined subjects' bids for one St.~Petersburg gamble with a real monetary payment. We found that bids were typically lower than twice the smallest payoff, and thus much lower than is generally supposed. We also examined bids offered for several hypothetical variants of the St.~Petersburg Paradox. We found that bids were weakly affected by truncating the gamble, were strongly affected by repeats of the gamble, and depended linearly on the initial ``seed'' value of the gamble. One explanation, which we call the extit{median} extit{heuristic}, strongly predicts these data. Subjects following this strategy evaluate a gamble as if they were taking the median rather than the mean of the payoff distribution. Finally, we argue that the distribution of outcomes embodied in the St.~Petersburg paradox is so divergent from the Gaussian form that the statistical mean is a poor estimator of expected value, so that the expected value of the St.~Petersburg gamble is undefined. These results suggest that this classic paradox has a straightforward explanation rooted in the use of a statistical heuristic.

Fossil fuels in the 21st century.

Science.gov (United States)

Lincoln, Stephen F

2005-12-01

An overview of the importance of fossil fuels in supplying the energy requirements of the 21st century, their future supply, and the impact of their use on global climate is presented. Current and potential alternative energy sources are considered. It is concluded that even with substantial increases in energy derived from other sources, fossil fuels will remain a major energy source for much of the 21st century and the sequestration of CO2 will be an increasingly important requirement.

Fort St. Vrain circulator operating experience

International Nuclear Information System (INIS)

Brey, H.L.

1988-01-01

Fort St. Vrain, on the system of Public Service Company of Colorado, is the only high-temperature gas-cooled power reactor in the United States. Four helium circulators are utilized in this plant to transfer heat from the reactor to the steam generators. These unique machines have a single stage axial flow helium compressor driven by a single stage steam turbine. A single stage water driven (pelton wheel) turbine is the back-up drive utilizing either feed water, condensate, or fire water as the driving fluid. Developmental testing of the circulators was accomplished prior to installation into Fort St. Vrain. A combined machine operating history of approximately 250,000 hours has shown these machines to be of conservative design and proven mechanical integrity. However, many problems have been encountered in operating the complex auxiliaries which are necessary for successful circulator and plant operation. It has been 15 years since initial installation of the circulators occurred at Fort St. Vrain. During this time, a number of significant issues had to be resolved dealing specifically with machine performance. These events include cavitation damage of the pelton wheels during the initial plant hot functional testing, cracks in the water turbine buckets and cervic coupling, static shutdown seal bellows failure, and, most recently, degradation of components within the steam drive assembly. Unreliable operation particularly with the circulator auxiliaries has been a focus of attention by Public Service Company of Colorado. Actions to replace or significantly modify the existing circulators and their auxiliaries are currently awaiting decisions concerning the long-term future of the Fort St. Vrain plant. (author). 10 refs, 7 figs, 2 tabs

Fort St. Vrain circulator operating experience

Energy Technology Data Exchange (ETDEWEB)

Brey, H. L.

1988-08-15

Fort St. Vrain, on the system of Public Service Company of Colorado, is the only high-temperature gas-cooled power reactor in the United States. Four helium circulators are utilized in this plant to transfer heat from the reactor to the steam generators. These unique machines have a single stage axial flow helium compressor driven by a single stage steam turbine. A single stage water driven (pelton wheel) turbine is the back-up drive utilizing either feed water, condensate, or fire water as the driving fluid. Developmental testing of the circulators was accomplished prior to installation into Fort St. Vrain. A combined machine operating history of approximately 250,000 hours has shown these machines to be of conservative design and proven mechanical integrity. However, many problems have been encountered in operating the complex auxiliaries which are necessary for successful circulator and plant operation. It has been 15 years since initial installation of the circulators occurred at Fort St. Vrain. During this time, a number of significant issues had to be resolved dealing specifically with machine performance. These events include cavitation damage of the pelton wheels during the initial plant hot functional testing, cracks in the water turbine buckets and cervic coupling, static shutdown seal bellows failure, and, most recently, degradation of components within the steam drive assembly. Unreliable operation particularly with the circulator auxiliaries has been a focus of attention by Public Service Company of Colorado. Actions to replace or significantly modify the existing circulators and their auxiliaries are currently awaiting decisions concerning the long-term future of the Fort St. Vrain plant. (author). 10 refs, 7 figs, 2 tabs.

St. Lawrence action plan meter

Energy Technology Data Exchange (ETDEWEB)

NONE

1992-12-31

The purpose of this bulletin is to report on the progress achieved under the St. Lawrence Action Plan. Under each of the Action Plan`s five objectives, it outlines environmental management indicators which identify actions taken and shows the results. This report presents the data collected in late August 1992 on the activities carried out by all partners of both governments involved in SLAP. The objectives examined in the bulletin are: to reduce by 90% the liquid toxic waste discharged by the 50 plants targeted for priority action; to prepare remediation plans for contaminated federal sites and restore wetlands; to conserve 5000 additional hectares of habitat and create a marine park; to develop and implement recovery plans for mammals, fish, birds, amphibians, reptiles, and plants; and to determine the state of the St. Lawrence River.

Influence of ST-segment recovery on infarct size and ejection fraction in patients with ST-segment elevation myocardial infarction receiving primary percutaneous coronary intervention

DEFF Research Database (Denmark)

Hallén, Jonas; Ripa, Maria Sejersten; Johanson, Per

2010-01-01

In patients with ST-segment elevation myocardial infarction treated with fibrinolytics, electrocardiogram-derived measures of ST-segment recovery guide therapy decisions and predict infarct size. The comprehension of these relationships in patients undergoing mechanical reperfusion is limited. We...

Examining the 21st Century Classroom: Developing an Innovation Configuration Map

Science.gov (United States)

Donovan, Loretta; Green, Tim D.; Mason, Candice

2014-01-01

Despite it being the second decade of the 21st century, there still exists a range of definitions of what a 21st century learning environment is. This can be troublesome for teacher educators as we strive to prepare teachers for environments we can't clearly describe. In order to describe a 21st century learning environment, we developed an IC Map…

Cleavage of ST6Gal I by Radiation-Induced BACE1 Inhibits Golgi-Anchored ST6Gal I-Mediated Sialylation of Integrin β1 and Migration in Colon Cancer Cells

International Nuclear Information System (INIS)

Lee, Minyoung; Park, Jung-Jin; Ko, Young-Gyu; Lee, Yun-Sil

2012-01-01

Previously, we found that β-galactoside α2,6-sialyltransferase (ST6Gal I), an enzyme that adds sialic acids to N-linked oligosaccharides of glycoproteins and is frequently overexpressed in cancer cells, is up-regulated by ionizing radiation (IR) and cleaved to a form possessing catalytic activity comparable to that of the Golgi-localized enzyme. Moreover, this soluble form is secreted into the culture media. Induction of ST6Gal I significantly increased the migration of colon cancer cells via sialylation of integrin β1. Here, we further investigated the mechanisms underlying ST6Gal I cleavage, solubilization and release from cells, and addressed its functions, focusing primarily on cancer cell migration. We performed immunoblotting and lectin affinity assay to analyze the expression of ST6 Gal I and level of sialylated integrin β1. After ionizing radiation, migration of cells was measured by in vitro migration assay. α2, 6 sialylation level of cell surface was analyzed by flow cytometry. Cell culture media were concentrated and then analyzed for soluble ST6Gal I levels using an α2, 6 sialyltransferase sandwich ELISA. We found that ST6Gal I was cleaved by BACE1 (β-site amyloid precursor protein-cleaving enzyme), which was specifically overexpressed in response to IR. The soluble form of ST6Gal I, which also has sialyltransferase enzymatic activity, was cleaved from the Golgi membrane and then released into the culture media. Both non-cleaved and cleaved forms of ST6Gal I significantly increased colon cancer cell migration in a sialylation-dependent manner. The pro-migratory effect of the non-cleaved form of ST6Gal I was dependent on integrin β1 sialylation, whereas that of the cleaved form of ST6Gal I was not, suggesting that other intracellular sialylated molecules apart from cell surface molecules such as integrin β1 might be involved in mediating the pro-migratory effects of the soluble form of ST6Gal I. Moreover, production of soluble form ST6Gal I by

Influence of ST-segment recovery on infarct size and ejection fraction in patients with ST-segment elevation myocardial infarction receiving primary percutaneous coronary intervention

DEFF Research Database (Denmark)

Hallén, Jonas; Ripa, Maria Sejersten; Johanson, Per

2010-01-01

percutaneous coronary intervention. Three methods for calculating and categorizing ST-segment recovery were used: (1) summed ST-segment deviation (STD) resolution analyzed in 3 categories (> or = 70%, > or = 30% to or = 2 mm). Infarct size and ejection fraction were assessed at 4 months by cardiac magnetic...... resonance imaging. All 3 ST-segment recovery algorithms predicted the final infarct size and cardiac function. Worst-lead residual STD performed the same as, or better than, the more complex methods and identified large subgroups at either end of the risk spectrum (median infarct size from the lowest...

Evolutionary history of the alpha2,8-sialyltransferase (ST8Sia) gene family: tandem duplications in early deuterostomes explain most of the diversity found in the vertebrate ST8Sia genes.

Science.gov (United States)

Harduin-Lepers, Anne; Petit, Daniel; Mollicone, Rosella; Delannoy, Philippe; Petit, Jean-Michel; Oriol, Rafael

2008-09-23

The animal sialyltransferases, which catalyze the transfer of sialic acid to the glycan moiety of glycoconjugates, are subdivided into four families: ST3Gal, ST6Gal, ST6GalNAc and ST8Sia, based on acceptor sugar specificity and glycosidic linkage formed. Despite low overall sequence identity between each sialyltransferase family, all sialyltransferases share four conserved peptide motifs (L, S, III and VS) that serve as hallmarks for the identification of the sialyltransferases. Currently, twenty subfamilies have been described in mammals and birds. Examples of the four sialyltransferase families have also been found in invertebrates. Focusing on the ST8Sia family, we investigated the origin of the three groups of alpha2,8-sialyltransferases demonstrated in vertebrates to carry out poly-, oligo- and mono-alpha2,8-sialylation. We identified in the genome of invertebrate deuterostomes, orthologs to the common ancestor for each of the three vertebrate ST8Sia groups and a set of novel genes named ST8Sia EX, not found in vertebrates. All these ST8Sia sequences share a new conserved family-motif, named "C-term" that is involved in protein folding, via an intramolecular disulfide bridge. Interestingly, sequences from Branchiostoma floridae orthologous to the common ancestor of polysialyltransferases possess a polysialyltransferase domain (PSTD) and those orthologous to the common ancestor of oligosialyltransferases possess a new ST8Sia III-specific motif similar to the PSTD. In osteichthyans, we have identified two new subfamilies. In addition, we describe the expression profile of ST8Sia genes in Danio rerio. Polysialylation appeared early in the deuterostome lineage. The recent release of several deuterostome genome databases and paralogons combined with synteny analysis allowed us to obtain insight into events at the gene level that led to the diversification of the ST8Sia genes, with their corresponding enzymatic activities, in both invertebrates and vertebrates. The

Evolutionary history of the alpha2,8-sialyltransferase (ST8Sia gene family: Tandem duplications in early deuterostomes explain most of the diversity found in the vertebrate ST8Sia genes

Directory of Open Access Journals (Sweden)

Petit Jean-Michel

2008-09-01

Full Text Available Abstract Background The animal sialyltransferases, which catalyze the transfer of sialic acid to the glycan moiety of glycoconjugates, are subdivided into four families: ST3Gal, ST6Gal, ST6GalNAc and ST8Sia, based on acceptor sugar specificity and glycosidic linkage formed. Despite low overall sequence identity between each sialyltransferase family, all sialyltransferases share four conserved peptide motifs (L, S, III and VS that serve as hallmarks for the identification of the sialyltransferases. Currently, twenty subfamilies have been described in mammals and birds. Examples of the four sialyltransferase families have also been found in invertebrates. Focusing on the ST8Sia family, we investigated the origin of the three groups of α2,8-sialyltransferases demonstrated in vertebrates to carry out poly-, oligo- and mono-α2,8-sialylation. Results We identified in the genome of invertebrate deuterostomes, orthologs to the common ancestor for each of the three vertebrate ST8Sia groups and a set of novel genes named ST8Sia EX, not found in vertebrates. All these ST8Sia sequences share a new conserved family-motif, named "C-term" that is involved in protein folding, via an intramolecular disulfide bridge. Interestingly, sequences from Branchiostoma floridae orthologous to the common ancestor of polysialyltransferases possess a polysialyltransferase domain (PSTD and those orthologous to the common ancestor of oligosialyltransferases possess a new ST8Sia III-specific motif similar to the PSTD. In osteichthyans, we have identified two new subfamilies. In addition, we describe the expression profile of ST8Sia genes in Danio rerio. Conclusion Polysialylation appeared early in the deuterostome lineage. The recent release of several deuterostome genome databases and paralogons combined with synteny analysis allowed us to obtain insight into events at the gene level that led to the diversification of the ST8Sia genes, with their corresponding enzymatic

Bulding and Ornamental Stone in the History of St Petersburg Architecture

Science.gov (United States)

Bulakh, Andrey

2013-04-01

First, the Our Lady of Kazan Orthodox Cathedral and some mansions are used to demonstrate Russian stones in the architectural décor of St Petersburg, XVIII-XX cc. These rocks are granites from Vyborg and Sortavala, lime tufa from Gatchina, marbles from Ruskeala and Juven at the Ladoga Lake, Tivdian marble, Shokshian quartzite, and black aspid slate of the Onega Lake. Later German and Polish sandstones and Finnish soap stone came to the city. Second, there is given a review of rock types used in St Petersburg at XX-XXI cc. margins. They are granites, granosyenites, syenites, gneisses, marbles, limestones both from Russia and from abroad. Which ones are more usual? From what regions did Russian stone come? References: 1) A.G.Bulakh, N.B.Abakumova, J.V.Romanovsky. St Petersburg: a History in Stone. 2010. Print. House of St Petersburg State University. 173 p. 2) A.Ya. Tutakova, A.Z. Romanovskiy, A.G. Bulakh, V.I. Leer. Dimension Stone of the Leningrad Region. Granites of the Karelia Isthmus in Architecture of the Modern St Petersburg. 2011. St Petersburg. 78 p. (In Russian).

Simple stålrammebygninger

DEFF Research Database (Denmark)

Ellum, J.C.; Buhelt, M.

Ved en simpel stålrammebygning forstås i anvisningen en lukket, fritliggende bygning i én etage, hvor tagkonstruktionen ud over egenlast kun er påvirket af naturlaster, dvs. sne og vind. Dimensioneringen af de bærende konstruktioner gennemføres ved at benytte publikationens omfattende tabeldata o...

The structural features of the sulfated heteropolysaccharide (ST-1) from Sargassum thunbergii and its neuroprotective activities.

Science.gov (United States)

Jin, Weihua; Liu, Bing; Li, Shuai; Chen, Jing; Tang, Hong; Jiang, Di; Zhang, Quanbin; Zhong, Weihong

2018-03-01

Polysaccharide (ST) was prepared from Sargassum thunbergii using hot water. Two fractions (ST-1 and ST-2) were prepared using anion exchange chromatography. One desulfated polysaccharide (ST-1-DS) was also prepared. Electrospray ionization mass spectrometry (ESI-MS) performed on ST-1-DS showed that the desulfated polysaccharides contained methyl glycosides of mono-sulfated and di-sulfated galacto-fucooligosaccharides. This result suggested that ST-1 might contain sulfated galactofucan, which consists of a backbone of alternating (Gal) n and (Fuc) n and sulfated randomly on Gal and mainly on C-2 in Fuc. In addition, ST-1 was degraded in 1M sulfuric acid. The solution was centrifuged, and the supernatant was concentrated and precipitated in ethanol to obtain the precipitate (ST-1-P). ST-1-P was then separated using gel chromatography and anion exchange chromatography to obtain the oligomers. ESI-MS spectra of oligomers indicated that ST-1 mostly contained sulfated glucuronomannan and fucoglucuronan. ESI-MS with collision-induced dissociation tandem mass spectrometry (ESI-CID-MS/MS) suggested that glucuronomannan contained alternating 2-linked Man and 4-linked GlcA, while fucoglucuronan contained 4-linked glucuronan with branched Fuc at C-3. Finally, the neuroprotective activities of ST, ST-1, ST-2 and MIX (a mixture of ST-1 and ST-2) were determined. ST showed the most neuroprotective activity, which indicated that ST might be a good candidate for curing neurodegenerative diseases. Copyright © 2017 Elsevier B.V. All rights reserved.

Inferior ST-Elevation Myocardial Infarction Associated with Takotsubo Cardiomyopathy

Directory of Open Access Journals (Sweden)

Oliver Koeth

2010-01-01

Full Text Available Takotsubo cardiomyopathy (TCM is usually characterized by transient left ventricular apical ballooning. Due to the clinical symptoms which include chest pain, electrocardiographic changes, and elevated myocardial markers, Takotsubo cardiomyopathy is frequently mimicking ST-elevation myocardial infarction in the absence of a significant coronary artery disease. Otherwise an acute occlusion of the left anterior descending coronary artery can produce a typical Takotsubo contraction pattern. ST-elevation myocardial infarction (STEMI is frequently associated with emotional stress, but to date no cases of STEMI triggering TCM have been reported. We describe a case of a female patient with inferior ST-elevation myocardial infarction complicated by TCM.

Detection of ST-T Episode Based on the Global Curvature of Isoelectric Level in ECG

Energy Technology Data Exchange (ETDEWEB)

Kang, D. W.; Jun, D. G.; Lee, K. J.; Yoon, H. R. [Yonsei University, Seoul (Korea)

2001-04-01

This paper describes an automated detection algorithm of ST-T episodes using global curvature which can connect the isoelectric level in ECG and can eliminate not only the slope of ST segment, but also difference of the baseline and global curve. This above method of baseline correction is very faster than classical baseline correction methods. The optimal values of parameters for baseline correction were found as the value having the highest detection rate of ST episode. The features as input of backpropagation Neural Network were extracted from the whole ST segment. The European ST-T database was used as training and test data. Finally, ST elevation, ST depression and normal ST were classified. The average ST episode sensitivity and predictivity were 85.42%, 80.29%, respectively. This result shows the high speed and reliability in ST episode detection. In conclusion, the proposed method showed the possibility in various applications for the Holter system. (author). 17 refs., 5 figs., 4 tabs.

Kalkgraslandvegetaties van de St. Pietersberg ten zuiden van Maastricht

NARCIS (Netherlands)

Willems, J.H.; Blanckenborg, F.G.

1975-01-01

In this publication the authors describe the grassland communities rich in species especially those which occur on basic soils. The investigation was done in the Belgian part as well as in the Dutch part of St. Pietersberg situated south of the Dutch town of Maastricht. See map – fig. 1. St.

Merging formation of FRC and its application to high-beta ST formation

International Nuclear Information System (INIS)

Ono, Y.; Inomoto, M.; Ueda, Y.; Matsuyama, T.; Ohshima, Y.; Katsurai, M.

2001-01-01

Merging formation of field-reversed configuration (FRC) explored not only a new scenario of highly-efficient FRC formation/amplification experiment but also a new boundary research between FRC, spheromak and spherical tokamak (ST). A new finding is that the produced FRC is transformed stably into an ultra-high-β ST by applying external toroidal field B t,ext . The toroidal field was observed to vanish around magnetic axis after the B t,ext application to the FRC, indicating formation of diamagnetic ST. The hollow current profile of FRC was maintained during the equilibrium transition, eliminating a need for the difficult hollow-current-formation process of start-up discharge of high-β ST. The energy-conversion effect of merging transformed the force-free merging spheromaks with paramagnetic current into the FRC with diamagnetic current and the further application of B t,ext did the FRC into the ultra-high-β (>60%)/diamagnetic ST, indicating the close relationship between FRC and ST in second stability. (author)

ST Elevation in AVR: When Time May Not Mean Muscle

Science.gov (United States)

2017-10-31

REPORT TYPE 1013112017 Presentation 4. TITLE AND SUBTITLE ST Elevation in AVR: When Thne May Not Mean !Vfu&cle 6. AUTHOR{S) Capt \\Villiam T...ACCF/AHA Guideline for the Management of ST -Elevation Myocardial Infarction A Report of the Arnerican College of C ardiology Foundation/ Ameri can...C7Q n ([) G) ro )::>t w :J r+ c.. < -· ro ti) ti) ro ti) OJ m ti) -ro n Take home points •Don’t ignore ST elevation in aVR •Look closely

LiDAR Relative Reflectivity Surface (2011) for the St. Thomas East End Reserve, St. Thomas

Data.gov (United States)

National Oceanic and Atmospheric Administration, Department of Commerce — This image represents a LiDAR (Light Detection & Ranging) 0.3x0.3 meter resolution relative seafloor reflectivity surface for the St. Thomas East End Reserve...

"Vi er ikke støttepædagoer"

DEFF Research Database (Denmark)

Knudsen, Louise Stjerne

2014-01-01

Hvilket talent(udviklings)miljø har talentfulde gymnasieelever brug for, og hvordan ’plejer’ man dem bedst muligt, så de ikke føler, at de bliver ’støttepædagoger’?......Hvilket talent(udviklings)miljø har talentfulde gymnasieelever brug for, og hvordan ’plejer’ man dem bedst muligt, så de ikke føler, at de bliver ’støttepædagoger’?...

The Danish St. Croix Project

DEFF Research Database (Denmark)

J. Douma, Michael; Rasmussen, Anders Bo

2014-01-01

H. Seward, commonly viewed as an anti-colonizationist, was at least a mild proponent of colonization in its earliest stages. The paper demonstrates further that in the summer of 1862 the St. Croix colonization project was an important stepping stone in the Lincoln administration’s legal......Working from previously unknown sources in Danish archives, this article establishes for the first time the important role that the island of St. Croix played in the Lincoln Administration’s considerations on colonizing African Americans abroad. The paper argues that U.S. Secretary of State William....... The substantial conclusion of the paper is that, contrary to earlier perceptions in the historiography, African American colonization during the Civil War was not led and directed entirely from Washington. Rather, in this case, the Danish minister proposed a colonization plan and then worked with the United...

46 CFR 7.85 - St. Simons Island, GA to Little Talbot Island, FL.

Science.gov (United States)

2010-10-01

... 46 Shipping 1 2010-10-01 2010-10-01 false St. Simons Island, GA to Little Talbot Island, FL. 7.85... BOUNDARY LINES Atlantic Coast § 7.85 St. Simons Island, GA to Little Talbot Island, FL. (a) A line drawn from latitude 31°04.1′ N. longitude 81°16.7′ W. (St. Simons Lighted Whistle Buoy “ST S”) to latitude 30...

Aligning Business and Education: 21st Century Skill Preparation

Science.gov (United States)

Campbell, Charles L., Jr.; Kresyman, Shelley

2015-01-01

The purpose of this paper is to explore stakeholder perceptions concerning four key 21st century skills required for graduates to be successful in today's workplace, and to report on common themes surrounding how a post-secondary school in the Southwest United States is preparing graduates with predominant 21st Century skills: interpersonal…

Preparing Students for the Future--21st Century Skills

Science.gov (United States)

Velez, Alejandra

2012-01-01

The 21st century economy is driven by information and communication technologies (ICT). This change has made innovation, manufacturing and production of products and services, rather than manufacturing of material goods, the driving force of economies of leading countries (Wagner, 2008). Due to this shift, today's 21st century society and…

Hmong Political Involvement in St. Paul, Minnesota and Fresno, California

Directory of Open Access Journals (Sweden)

Yang Lor

2010-01-01

Full Text Available Over the past several years, Hmong in the United States have gained prominence for their increasing involvement in politics. Most of the attention has understandably focused on Fresno, California and St. Paul, Minnesota, home to the two largest Hmong populations in this country. While the Hmong communities in both cities are similar in size and have made significant political progress as evidenced by the election of Hmong candidates, the Hmong community in St. Paul has made greater inroads in the political realm. In addition to the elections of two Hmong candidates to the Minnesota State Legislature and two to the St. Paul School Board, the Hmong community in St. Paul has been able to engage local and state governments in Minnesotato address issues that affect the Hmong community. Through interviews, census data, and newspaper coverage of political campaigns, I show that Hmong in St. Paul have achieved greaterrepresentation in local and state governments and received greater support from government officials than Hmong in Fresno because Minnesota offers a social, economic, and politicalcontext that is favorable to fostering Hmong political involvement. Compared to Hmong in Fresno, Hmong in St. Paul have higher levels of socioeconomic resources and are more visible given their large size relative to other minority groups. They live in a region with consistently high levels of political participation and have political candidates who devote resources to mobilizing the Hmong community. Moreover, the Hmong vote has been critical to the success of Hmong candidates in St. Paul, an indication of the increasing political clout of the Hmong community there and a major reason why politicians in Minnesota are more willing to respond toissues that affect the Hmong community. Overall, this study highlights the importance of local and regional context in understanding the political incorporation of immigrants.

Projections of Climate Change over China for the 21st Century

Institute of Scientific and Technical Information of China (English)

LUO Yong; ZHAO Zongci; XU Ying; GAO Xuejie; DING Yihui

2005-01-01

The projections of climate changes in China for the 21st century by about 40 climate scenarios and multi-model ensembles have been investigated in this research. All the models with the different scenarios project a warming of 1.2℃ to 9.2℃ in China by the end of 21st century. Most of the projections point show the increasing of precipitation in China for the 21st century.

Molecular Characterization of Methicillin-Resistant Staphylococcus aureus from Outpatients in Northern Japan: Increasing Tendency of ST5/ST764 MRSA-IIa with Arginine Catabolic Mobile Element.

Science.gov (United States)

Aung, Meiji Soe; Kawaguchiya, Mitsuyo; Urushibara, Noriko; Sumi, Ayako; Ito, Masahiko; Kudo, Kenji; Morimoto, Shigeo; Hosoya, Shino; Kobayashi, Nobumichi

2017-07-01

Arginine catabolic mobile element (ACME) is a genomic island of staphylococcus and is considered to confer enhanced ability to survive and growth on host bacterial cells. ACME has been typically identified in Panton-Valentine Leukocidin (PVL)-positive ST8 methicillin-resistant Staphylococcus aureus (MRSA) with SCCmec type IVa (USA300 clone), and it is also found in other lineages at low frequency. Prevalence and molecular characteristics of PVL + and/or ACME + MRSA were investigated for 624 clinical isolates collected from outpatients in northern Japan from 2013 to 2014. Both PVL genes and ACME type I were detected in nine isolates (1.4%), which were ST8-MRSA-SCCmec IVa/spa type t008/agr-I; whereas solely PVL genes were positive in two isolates, ST30-MRSA-SCCmec IV and ST59-MRSA-SCCmec V. ACME type II' (previously referred to as ACME ΔII) was detected in 36 isolates (5.8%) with SCCmec II and V (32 and 4 isolates, respectively), exhibiting an increased rate within SCCmec II-MRSA (7.1%) compared with our previous studies (0.86-4.5%, 2008-2011). ACME II'-positive MRSA strains were classified into ST5-SCCmec IIa/V or ST764-SCCmec IIa belonging to five different spa types, with t002 being dominant. They harbored mostly enterotoxin gene clusters (seg-sei-sem-sen-seo-seu) and some more enterotoxin genes (seb1, seb2, sec3, sel, sep), showing resistance to more antimicrobials than ST8-MRSA-SCCmec IVa. ACME-SCCmec composite island (CI) of the 36 ACME II'-positive MRSA was classified into five types (ii)-(vi), among which type (ii) (orfX-ΨSCC ΔJ1 SCCmec I -ACME II'-SCCmec II) was dominant and subdivided into the A3 variant and the less common A2 variant. CI types (v) and (vi) were considered novel genetic organizations having speG (acetyltransferase genes for polyamines) in inserted SCC4610/SCC266-like genetic elements. The present study revealed increased prevalence and genetic diversity of the ST5/ST764-MRSA-SCCmec II with ACME II' in northern Japan.

21st centuries skill implication on educational system

Science.gov (United States)

Wrahatnolo, T.; Munoto

2018-01-01

The purpose of this article is to identify skill needed in 21st centuries and its implication on Indonesia’s educational system. This research found that the 21st centuries skill application has more measurable benefits in some sections of life, such as critical thinking and problem solving, initiative, creativity, and entrepreneurship, communication, teamwork, metacognition (change of mindset), digital literature. This study applied qualitative data analysis. The data were taken from different sources and literature. The analysis showed that The 21st centuries education concept’s implementation can be applied in the curriculum of the required subject that is addressed to achieve learning and innovation skills competence and also technology and information media skills competence. While supporting subject group directed to achieve life and career skills competence. All subjects are the derivation from core subject 3R, which are reading, writing, and arithmetic. Based on the description above, it can be concluded that 21st centuries skill needs; (1) a life planning; (2) flexibility and adaptability; (3) initiative and self-management (4) entrepreneurship; (5) social and cultural interaction; (6) productivity and accountability; (7) leadership; (8) critical thinking, (9) problem solving; (10) communication; (11) collaboration and teamwork; (12) lifelong learning; and (13) digital literation.

Anstrengelsesinduceret ST-segmentdepression efter akut myokardieinfarkt. Forekomst og prognostisk betydning

DEFF Research Database (Denmark)

Mickley, H; Pless, P; May, O

1989-01-01

On the basis of a review of 20 investigations (3,587 patients), the prevalence of significant ST-segment-depression (ST-depr) in patients performing an exercise test 9-30 days after acute myocardial infarction (AMI) was found to be 33% (3-70%). The reason for the considerable variation is due...... to a combination of several factors: 1) different and frequently incomplete definition of significant ST-depr; 2) heterogenically composed patient groups (first vs subsequent AMI, different prevalence of infarct types and localization, consecutive vs selected patients, +/- cardioactive drugs during the exercise...

Constructive singularities and energy efficiency of St. Petersburg historic circuses

Science.gov (United States)

Sysoeva, Elena; Trushina, Ekaterina

2017-10-01

The article is devoted to the design and construction of St. Petersburg circuses during the period since 1822 till nowadays. The article presents the characteristics of all eight historic buildings of St. Petersburg and their structural and architectural features. The article raises some issues of energy-optimal shape of a building on the example of St. Petersburg modern circus building. There are several historical drawings and photographs of the circus buildings. The article includes overview of normative regulation of circus buildings in Russia since the middle of the twentieth century and prospects for the future.

Department of Energy: Nuclear S&T workforce development programs

International Nuclear Information System (INIS)

Bingham, Michelle; Bala, Marsha; Beierschmitt, Kelly; Steele, Carolyn; Sattelberger, Alfred P.; Bruozas, Meridith A.

2016-01-01

The U.S. Department of Energy (DOE) national laboratories use their expertise in nuclear science and technology (S&T) to support a robust national nuclear S&T enterprise from the ground up. Traditional academic programs do not provide all the elements necessary to develop this expertise, so the DOE has initiated a number of supplemental programs to develop and support the nuclear S&T workforce pipeline. This document catalogs existing workforce development programs that are supported by a number of DOE offices (such as the Offices of Nuclear Energy, Science, Energy Efficiency, and Environmental Management), and by the National Nuclear Security Administration (NNSA) and the Naval Reactor Program. Workforce development programs in nuclear S&T administered through the Department of Homeland Security, the Nuclear Regulatory Commission, and the Department of Defense are also included. The information about these programs, which is cataloged below, is drawn from the program websites. Some programs, such as the Minority Serving Institutes Partnership Programs (MSIPPs) are available through more than one DOE office, so they appear in more than one section of this document.

Orthophoto Mosaic (2012) of the St. Thomas East End Reserve

Data.gov (United States)

National Oceanic and Atmospheric Administration, Department of Commerce — This 0.3x0.3 meter imagery mosaic of the St. Thomas East End Reserve (STEER), St. Thomas in the U.S. Virgin Islands was created by the National Oceanic and...

Building a Stückelberg portal

Energy Technology Data Exchange (ETDEWEB)

Feng, Wan-Zhe [Center for Fundamental Physics and Institute for Advanced Study,Hong Kong University of Science and Technology (Hong Kong); Max-Planck-Institut für Physik (Werner-Heisenberg-Institut),80805 München (Germany); Shiu, Gary; Soler, Pablo; Ye, Fang [Center for Fundamental Physics and Institute for Advanced Study,Hong Kong University of Science and Technology (Hong Kong); Department of Physics, University of Wisconsin,Madison, WI 53706 (United States)

2014-05-15

We construct explicit string theory models realizing the recently proposed “Stückelberg Portal” scenario, a framework for building Z{sup ′} mediation models without the need to introduce unwanted exotic matter charged under the Standard Model. This scenario can be viewed purely field-theoretically, although it is particularly well motivated from string theory. By analyzing carefully the Stückelberg couplings between the Abelian gauge bosons and the RR axions, we construct the first global intersecting brane models which extend the Standard Model with a genuine hidden sector, to which it is nonetheless connected via U(1) mass mixings. Utilizing the explicit models we construct, we discuss some broad phenomenological properties and experimental implications of this scenario such as Z−Z{sup ′} mixings, dark matter stability and relic density, and supersymmetry mediation. With an appropriate confining hidden sector, our setup also provides a minimal realization of the hidden valley scenario. We further explore the possibility of obtaining small Z{sup ′} masses from a large ensemble of U(1) bosons. Related to the Stückelberg portal are two mechanisms that connect the visible and the hidden sectors, namely mediation by non-perturbative operators and the hidden photon scenario, on which we briefly comment.

AM-37 and ST-36 Are Small Molecule Bombesin Receptor Antagonists.

Science.gov (United States)

Moody, Terry W; Tashakkori, Nicole; Mantey, Samuel A; Moreno, Paola; Ramos-Alvarez, Irene; Leopoldo, Marcello; Jensen, Robert T

2017-01-01

While peptide antagonists for the gastrin-releasing peptide receptor (BB 2 R), neuromedin B receptor (BB 1 R), and bombesin (BB) receptor subtype-3 (BRS-3) exist, there is a need to develop non-peptide small molecule inhibitors for all three BBR. The BB agonist (BA)1 binds with high affinity to the BB 1 R, BB 2 R, and BRS-3. In this communication, small molecule BBR antagonists were evaluated using human lung cancer cells. AM-37 and ST-36 inhibited binding to human BB 1 R, BB 2 R, and BRS-3 with similar affinity ( K i = 1.4-10.8 µM). AM-13 and AM-14 were approximately an order of magnitude less potent than AM-37 and ST-36. The ability of BA1 to elevate cytosolic Ca 2+ in human lung cancer cells transfected with BB 1 R, BB 2 R, and BRS-3 was antagonized by AM-37 and ST-36. BA1 increased tyrosine phosphorylation of the EGFR and ERK in lung cancer cells, which was blocked by AM-37 and ST-36. AM-37 and ST-36 reduced the growth of lung cancer cells that have BBR. The results indicate that AM-37 and ST-36 function as small molecule BB receptor antagonists.

76 FR 77208 - Affirmation of Vertical Datum for Surveying and Mapping Activities for the Islands of St. Croix...

Science.gov (United States)

2011-12-12

... Datum for Surveying and Mapping Activities for the Islands of St. Croix, St. John, and St. Thomas... datum for surveying and mapping activities for the islands of St. Croix, St. John, and St. Thomas of the... by other Federal surveying and mapping agencies on St. Croix, St. John, and St. Thomas, with the...

Hemodialysis Infection Prevention Protocols Ontario—Shower Technique (HIPPO-ST: A Pilot Randomized Trial

Directory of Open Access Journals (Sweden)

S. Daisy Kosa

2017-03-01

Discussion: This HIPPO-ST pilot study demonstrated the feasibility of the larger HIPPO-ST study, especially given the high levels of education success with the HIPPO-ST arm and the low levels of contamination in the control arm.

The non-marine Mollusca of St. Martin (Lesser Antilles)

NARCIS (Netherlands)

Coomans, H.E.

1967-01-01

After our studies about the marine mollusks of St. Martin, (COOMANS 1963a, 1963b), this publication will deal with the land and freshwater shells of the island. The non-marine mollusks of St. Martin were already fairly well known at the end of the last century (MAZÉ 1890, p. 22—34), who mentioned 36

33 CFR 165.762 - Security Zone; St. Thomas, U.S. Virgin Islands.

Science.gov (United States)

2010-07-01

... 33 Navigation and Navigable Waters 2 2010-07-01 2010-07-01 false Security Zone; St. Thomas, U.S....762 Security Zone; St. Thomas, U.S. Virgin Islands. (a) Location. Moving and fixed security zones are established 50 yards around all cruise ships entering, departing, moored or anchored in the Port of St. Thomas...

Axial Fatigue Tests at Zero Mean Stress of 24S-T and 75S-T Aluminum-alloy Strips with a Central Circular Hole

Science.gov (United States)

Brueggeman, W C; Mayer, M JR

1948-01-01

Axial fatigue tests at zero mean stress have been made on 0.032- and 0.064-inch 24S-T and 0.032-inch 75S-T sheet-metal specimens 1/4, 1/2, 1, and 2 inches wide without a hole and with central holes giving a range of hole diameter D to specimen width W from 0.01 to 0.95. No systematic difference was noted between the results for the 0.032-inch and the 0.064-inch specimens although the latter seemed the more consistent. In general the fatigue strength based on the minimum section dropped sharply as the ration D/W was increased from zero to about 0.25. The plain specimens showed quite a pronounced decrease in fatigue strength with increasing width. The holed specimens showed only slight and rather inconclusive evidence of this size effect. The fatigue stress-concentration factor was higher for 75S-T than for 24S-T alloy. Evidence was found that a very small hole would not cause any reduction in fatigue strength.

ST product characteristics and relationships with perceptions and behaviors among rural adolescent males: a qualitative study.

Science.gov (United States)

Couch, Elizabeth T; Darius, Ellen F; Walsh, Margaret M; Chaffee, Benjamin W

2017-12-01

Although smoking declines in the United States, the prevalence of male adolescent smokeless tobacco (ST; moist snuff and chewing tobacco) use remains unchanged. ST product characteristics, such as flavoring, packaging, and branding, could influence adolescents' ST initiation and continued use. This qualitative study examines the potential role of product characteristics in shaping ST-related perceptions and behaviors among rural adolescent males. Semi-structured individual interviews were conducted at three California rural high schools. ST users were asked about their experiences and perceptions related to product characteristics. Interviews were transcribed, coded, and analyzed using a general inductive approach. Participants associated flavored ST with appealing non-tobacco products, such as chewing gum and alcohol. Availability of different varieties and flavors stimulated interest and curiosity in sampling or switching between ST products. Time-limited promotional flavors and packaging also enhanced product appeal. Adolescent ST users preferred certain brands based on perceived brand features and perceived nicotine content, associating higher-strength brands as better suited for experienced ST users. Brand preferences frequently reflected perceived ST brand popularity within peer groups. Based on these observations, potential ST regulation and health education campaigns to address misconceptions about ST characteristics could influence adolescents' ST-related perceptions and reduce ST use among this vulnerable population. © The Author 2017. Published by Oxford University Press. All rights reserved. For permissions, please email: journals.permissions@oup.com.

Minor Electrocardiographic ST-T Change and Risk of Stroke in the General Japanese Population.

Science.gov (United States)

Ishikawa, Joji; Hirose, Hideo; Schwartz, Joseph E; Ishikawa, Shizukiyo

2018-06-25

Minor ST-T changes are frequently observed on the electrocardiogram (ECG), but the risk of stroke associated with such changes is unclear.Methods and Results:In 10,642 subjects from the Japanese general population, we evaluated minor and major ST-T changes (major ST depression ≥0.1 mV) on ECGs obtained at annual health examinations. At baseline, minor ST-T changes were found in 10.7% of the subjects and 0.5% had major ST-T changes. Minor ST-T changes were associated with older age, female gender, higher systolic blood pressure, presence of hyperlipidemia, and use of antihypertensive medication. There were 375 stroke events during the follow-up period (128.7±28.1 months). In all subjects, minor ST-T changes (HR, 2.10; 95% CI: 1.57-2.81) and major ST-T changes (HR, 8.64; 95% CI: 4.44-16.82) were associated with an increased risk of stroke, but the stroke risk associated with minor ST-T changes had borderline significance after adjustment for conventional risk factors (P=0.055). In subgroup analysis, the risk of stroke was significantly associated with minor ST-T changes in subjects who had hyperlipidemia (HR, 1.75; 95% CI: 1.15-2.67) compared to those without hyperlipidemia (HR, 1.01; 95% CI: 0.64-1.59; P for interaction=0.016), even after adjustment for ECG-diagnosed left ventricular hypertrophy. Minor ST-T changes were particularly associated with a higher risk of stroke in subjects with hyperlipidemia and this association was independent of electrocardiographic left ventricular hypertrophy.

EKSPLORASI DAN PRODUKTIFITAS PADANG PENGGEMBALAAN DI KECAMATAN PAMONA TIMUR KABUPATEN POSO SULAWESI TENGAH

Directory of Open Access Journals (Sweden)

P.D.M.H. Karti

2015-06-01

Full Text Available Pasture in District of East Pamona, Poso Regency has potential as forage for livestock.. This study was conducted in two villages (Didiri and Kelei to explore of plant species as feed and productivity calculation such as botanical composition and carrying capacities. Type of grasses that grow are Sporobolus sp, Paspalum sp, Paspalum cartilagineum, Axonopus compresus, Euleusine indica. Type of legumes that grow are Stylosanthes guianensis, Desmodium sp, Centrocema pubescens, Callyandra callothyrsus, Leucaena leucocephala. Types of weeds have started to grow in several locations within the region, such as Melastoma, Mimosa pudica, Imperata cylindrica, Cromolena odorata, Cyperacea, and Lamtana camara. Botanical composition (% in Kelei for grass, legumes, weeds (84.76: 6.75: 8:49 and Didiri for grass, legumes, weeds (95.34: 0:51: 4.15. Carrying Capacities in Kelei and Didiri was 0.96 ± 0:23 and 1:12 ± 0:29 ST / ha.

Topical application of ST266 reduces UV-induced skin damage

Directory of Open Access Journals (Sweden)

Guan L

2017-11-01

Full Text Available Linna Guan,1 Amanda Suggs,1 Emily Galan,1 Minh Lam,1 Elma D Baron1,2 1Department of Dermatology, Case Western Reserve University, 2Cleveland Veterans Affairs Medical Center, Cleveland, OH, USA Abstract: Ultraviolet radiation (UVR has a significant impact on human skin and is the major environmental factor for skin cancer formation. It is also believed that 80% of the signs of skin aging are attributed to UVR. UVR induces inflammatory changes in the skin via the increase in oxidative stress, DNA damage vascular permeability, and fluctuation in a myriad of cytokines. Acutely, UVR causes skin inflammation and DNA damage, which manifest as sunburn (erythema. ST266 is the secretome of proprietary amnion-derived cells that have been shown to reduce inflammation and accelerate healing of various wounds by promoting migration of keratinocytes and fibroblasts in preclinical animal studies. We hypothesized that ST266 has anti-inflammatory effects that can be used to reduce ultraviolet (UV erythema and markers of inflammation. In this study, we examined the in vivo effects of ST266 on post UV-irradiated skin by measuring erythema, level of cyclobutane pyrimidine dimer (CPD, and expression level of xeroderma pigmentosum, complementation group A (XPA. We demonstrated that ST266 has the potential to reduce the acute effects of UV-induced skin damage when applied immediately after the initial exposure. In addition, ST266 is shown to reduce erythema, increase XPA DNA repair protein, and decrease damaged DNA. Keywords: ST266, photoaging, erythema, CPD, XPA, UV-induced DNA damage

Homogenate-assisted Vacuum-powered Bubble Extraction of Moso Bamboo Flavonoids for On-line Scavenging Free Radical Capacity Analysis.

Science.gov (United States)

Sun, Yinnan; Yang, Kui; Cao, Qin; Sun, Jinde; Xia, Yu; Wang, Yinhang; Li, Wei; Ma, Chunhui; Liu, Shouxin

2017-07-11

A homogenate-assisted vacuum-powered bubble extraction (HVBE) method using ethanol was applied for extraction of flavonoids from Phyllostachys pubescens (P. pubescens) leaves. The mechanisms of homogenate-assisted extraction and vacuum-powered bubble generation were discussed in detail. Furthermore, a method for the rapid determination of flavonoids by HPLC was established. HVBE followed by HPLC was successfully applied for the extraction and quantification of four flavonoids in P. pubescens , including orientin, isoorientin, vitexin, and isovitexin. This method provides a fast and effective means for the preparation and determination of plant active components. Moreover, the on-line antioxidant capacity, including scavenging positive ion and negative ion free radical capacity of different fractions from the bamboo flavonoid extract was evaluated. Results showed that the scavenging DPPH ˙ free radical capacity of vitexin and isovitexin was larger than that of isoorientin and orientin. On the contrary, the scavenging ABTS⁺ ˙ free radical capacity of isoorientin and orientin was larger than that of vitexin and isovitexin.

SOBREVIVENCIA Y CRECIMIENTO DE PLÁNTULAS DE TRES ESPECIES ARBÓREAS EN ÁREAS DE BOSQUE MONTANO ANDINO DEGRADADAS POR GANADERÍA EN COLOMBIA

Directory of Open Access Journals (Sweden)

Deisy Johanna Moreno-Betancur

2015-05-01

Full Text Available En la Región Lechera del centro de Antioquia el paisaje ha sido ampliamente transformado de bosques montanos a pastizales para pastoreo de ganado vacuno, siendo la restauración del paisaje en esta zona una acción primordial que debe ser incorporada en el plan de uso de la tierra. El objetivo general de este estudio fue seleccionar tres especies arbóreas que promuevan el proceso de regeneración de bosques montanos y evaluar el efecto de diferentes estrategias de siembra sobre el establecimiento de las plántulas. Se consideró el efecto del tipo de fertilización, combinación de especies, disponibilidad lumínica y niveles de precipitación sobre la sobrevivencia y crecimiento de las plántulas. Quercus humboldtii, Weinmannia pubescens y Myrsine coriacea fueron las especies seleccionadas por presentar alto índice de valor de importancia ecológica y alta disponibilidad de semillas. La fertilización orgánica favoreció la sobrevivencia de las tres especies evaluadas y el crecimiento para W. pubescens. La combinación de especies no afectó la tasa de crecimiento pero si la sobrevivencia. Se detectó también mayor sobrevivencia en las plántulas de las tres especies que recibieron sombra en algún momento del día; al contrario, disminuyó en la época de sequía. El éxito en el establecimiento de Q. humboldtii, la tolerancia de W. pubescens a las heladas y la dispersión de semillas de M. coriacea por aves son características que en conjunto convierten a estas especies en promisoras para procesos de restauración ecológica en áreas de bosque montano. ABSTRACT Mountain forest landscapes of the central region of Antioquia department (Colombia have been largely transformed into pastures; therefore, ecological restoration must be included as a primordial strategy. The aim of this study was the selection of three tree species that help to improve natural regeneration of mountain forest and to evaluate the effect of different sowing

Reliability and Validity of Michigan School Libraries for the 21st Century Measurement Benchmarks

Science.gov (United States)

Floyd, Natosha N.

2016-01-01

The purpose of this study was to examine the psychometric properties of the Michigan School Libraries for the 21st Century Measurement Benchmarks (SL21). The instrument consists of 19 items with three subscales: Building the 21st Century Learning Environment Subscale, Teaching for 21st Century Learning Subscale, and Leading the Way to 21st Century…

75 FR 32813 - St. Croix Chippewa Indians of Wisconsin Alcoholic Beverage Control Ordinance

Science.gov (United States)

2010-06-09

... DEPARTMENT OF THE INTERIOR Bureau of Indian Affairs St. Croix Chippewa Indians of Wisconsin...: This notice publishes the Secretary's certification of the amended St. Croix Chippewa Indians of... Country. The St. Croix Tribal Council of the adopted this amended Liquor Ordinance on December 3, 2009...

75 FR 21243 - Marine Mammals; Subsistence Taking of Northern Fur Seals; St. George

Science.gov (United States)

2010-04-23

... Mammals; Subsistence Taking of Northern Fur Seals; St. George AGENCY: National Marine Fisheries Service... (APA). The Pribilof Island Community of St. George Island, Traditional Council (Council) petitioned... St. George Island to take male fur seal young of the year during the fall. NMFS solicits public...

AM-37 and ST-36 Are Small Molecule Bombesin Receptor Antagonists

Directory of Open Access Journals (Sweden)

Terry W. Moody

2017-07-01

Full Text Available While peptide antagonists for the gastrin-releasing peptide receptor (BB2R, neuromedin B receptor (BB1R, and bombesin (BB receptor subtype-3 (BRS-3 exist, there is a need to develop non-peptide small molecule inhibitors for all three BBR. The BB agonist (BA1 binds with high affinity to the BB1R, BB2R, and BRS-3. In this communication, small molecule BBR antagonists were evaluated using human lung cancer cells. AM-37 and ST-36 inhibited binding to human BB1R, BB2R, and BRS-3 with similar affinity (Ki = 1.4–10.8 µM. AM-13 and AM-14 were approximately an order of magnitude less potent than AM-37 and ST-36. The ability of BA1 to elevate cytosolic Ca2+ in human lung cancer cells transfected with BB1R, BB2R, and BRS-3 was antagonized by AM-37 and ST-36. BA1 increased tyrosine phosphorylation of the EGFR and ERK in lung cancer cells, which was blocked by AM-37 and ST-36. AM-37 and ST-36 reduced the growth of lung cancer cells that have BBR. The results indicate that AM-37 and ST-36 function as small molecule BB receptor antagonists.

AM-37 and ST-36 Are Small Molecule Bombesin Receptor Antagonists

Science.gov (United States)

Moody, Terry W.; Tashakkori, Nicole; Mantey, Samuel A.; Moreno, Paola; Ramos-Alvarez, Irene; Leopoldo, Marcello; Jensen, Robert T.

2017-01-01

While peptide antagonists for the gastrin-releasing peptide receptor (BB2R), neuromedin B receptor (BB1R), and bombesin (BB) receptor subtype-3 (BRS-3) exist, there is a need to develop non-peptide small molecule inhibitors for all three BBR. The BB agonist (BA)1 binds with high affinity to the BB1R, BB2R, and BRS-3. In this communication, small molecule BBR antagonists were evaluated using human lung cancer cells. AM-37 and ST-36 inhibited binding to human BB1R, BB2R, and BRS-3 with similar affinity (Ki = 1.4–10.8 µM). AM-13 and AM-14 were approximately an order of magnitude less potent than AM-37 and ST-36. The ability of BA1 to elevate cytosolic Ca2+ in human lung cancer cells transfected with BB1R, BB2R, and BRS-3 was antagonized by AM-37 and ST-36. BA1 increased tyrosine phosphorylation of the EGFR and ERK in lung cancer cells, which was blocked by AM-37 and ST-36. AM-37 and ST-36 reduced the growth of lung cancer cells that have BBR. The results indicate that AM-37 and ST-36 function as small molecule BB receptor antagonists. PMID:28785244

The Gadaba and the "non-ST" Desia of Koraput, Orissa

NARCIS (Netherlands)

Berger, P.; Pfeffer, G.; Dehera, D.K.

2002-01-01

ABSTRACT: "Tribal studies" in Orissa (India) mainly focus on that part of the indigenous population of the hills, which is defined as " Scheduled Tribe" ("ST") by the administration. The southern-most Koraput District is no exception to that custom and the "non-ST" population of the region,

Tritium stripping in a nitrogen glovebox using SAES St 198

International Nuclear Information System (INIS)

Klein, J.E.; Wermer, J.R.

1994-01-01

SAES metal getter material St 198 was chosen for glovebox stripper tests to evaluate its effectiveness of removing tritium from a nitrogen atmosphere. The St 198 material is unique from a number of other metal hydride-based getter materials in that it is relatively inert to nitrogen and can thus be used in nitrogen glovebox atmospheres. Six tritium stripper experiments which mock-up the use of a SAES St 198 stripper bed for a full-scale (10,500 liter) nitrogen glovebox have been completed. Experiments consisted of a release of small quantity of protium/deuterium spiked with tritium which were scaled to simulate tritium releases of 0.1 g., 1.0 g., and 10 g. into the glovebox. The tritium spike allows detection using tritium ion chambers. The St 198 stripper system produced a reduction in tritium activity of approximately two orders of magnitude in 24 hours (6--8 atmosphere turn-overs) of stripper operation

File list: His.Lar.05.AllAg.1st_instar [Chip-atlas[Archive

Lifescience Database Archive (English)

Full Text Available His.Lar.05.AllAg.1st_instar dm3 Histone Larvae 1st instar SRX013088,SRX013009,SRX01...3064,SRX013044,SRX013097 http://dbarchive.biosciencedbc.jp/kyushu-u/dm3/assembled/His.Lar.05.AllAg.1st_instar.bed ...

File list: His.Lar.20.AllAg.1st_instar [Chip-atlas[Archive

Lifescience Database Archive (English)

Full Text Available His.Lar.20.AllAg.1st_instar dm3 Histone Larvae 1st instar SRX013009,SRX013088,SRX01...3044,SRX013064,SRX013097 http://dbarchive.biosciencedbc.jp/kyushu-u/dm3/assembled/His.Lar.20.AllAg.1st_instar.bed ...

File list: His.Lar.50.AllAg.1st_instar [Chip-atlas[Archive

Lifescience Database Archive (English)

Full Text Available His.Lar.50.AllAg.1st_instar dm3 Histone Larvae 1st instar SRX013009,SRX013088,SRX01...3044,SRX013064,SRX013097 http://dbarchive.biosciencedbc.jp/kyushu-u/dm3/assembled/His.Lar.50.AllAg.1st_instar.bed ...

File list: His.Lar.10.AllAg.1st_instar [Chip-atlas[Archive

Lifescience Database Archive (English)

Full Text Available His.Lar.10.AllAg.1st_instar dm3 Histone Larvae 1st instar SRX013088,SRX013064,SRX01...3044,SRX013009,SRX013097 http://dbarchive.biosciencedbc.jp/kyushu-u/dm3/assembled/His.Lar.10.AllAg.1st_instar.bed ...

76 FR 38357 - Reorganization of Foreign-Trade Zone 102, Under Alternative Site Framework; St. Louis, MO

Science.gov (United States)

2011-06-30

... Zone 102, Under Alternative Site Framework; St. Louis, MO Pursuant to its authority under the Foreign.../2010) as an option for the establishment or reorganization of general-purpose zones; Whereas, the St... the City of St. Louis and St. Louis County, Missouri, within and adjacent to the St. Louis Customs and...

Mount St. Helens aerosol evolution

Energy Technology Data Exchange (ETDEWEB)

Oberbeck, V.R.; Farlow, N.H.

1982-08-01

Stratospheric aerosol samples were collected using a wire impactor during the year following the eruption of Mount St. Helens. Analysis of samples shows that aerosol volume increased for 6 months due to gas-to-particle conversion and then decreased to background levels in the following 6 months.

Mount St. Helens aerosol evolution

Energy Technology Data Exchange (ETDEWEB)

Oberbeck, V.R.; Farlow, N.H.; Fong, W.; Snetsinger, K.G.; Ferry, G.V.; Hayes, D.M.

1982-09-01

Stratospheric aerosol samples were collected using a wire impactor during the year following the eruption of Mt. St. Helens. Analysis of samples show that aerosol volume increased for 6 months due to gas-to-particle conversion and then decreased to background levels in the following 6 months.

Interleukin-33 Receptor (ST2 Deficiency Improves the Outcome of Staphylococcus aureus-Induced Septic Arthritis

Directory of Open Access Journals (Sweden)

Larissa Staurengo-Ferrari

2018-05-01

Full Text Available The ST2 receptor is a member of the Toll/IL-1R superfamily and interleukin-33 (IL-33 is its agonist. Recently, it has been demonstrated that IL-33/ST2 axis plays key roles in inflammation and immune mediated diseases. Here, we investigated the effect of ST2 deficiency in Staphylococcus aureus-induced septic arthritis physiopathology. Synovial fluid samples from septic arthritis and osteoarthritis individuals were assessed regarding IL-33 and soluble (s ST2 levels. The IL-33 levels in samples from synovial fluid were significantly increased, whereas no sST2 levels were detected in patients with septic arthritis when compared with osteoarthritis individuals. The intra-articular injection of 1 × 107 colony-forming unity/10 μl of S. aureus American Type Culture Collection 6538 in wild-type (WT mice induced IL-33 and sST2 production with a profile resembling the observation in the synovial fluid of septic arthritis patients. Data using WT, and ST2 deficient (−/− and interferon-γ (IFN-γ−/− mice showed that ST2 deficiency shifts the immune balance toward a type 1 immune response that contributes to eliminating the infection due to enhanced microbicide effect via NO production by neutrophils and macrophages. In fact, the treatment of ST2−/− bone marrow-derived macrophage cells with anti-IFN-γ abrogates the beneficial phenotype in the absence of ST2, which confirms that ST2 deficiency leads to IFN-γ expression and boosts the bacterial killing activity of macrophages against S. aureus. In agreement, WT cells achieved similar immune response to ST2 deficiency by IFN-γ treatment. The present results unveil a previously unrecognized beneficial effect of ST2 deficiency in S. aureus-induced septic arthritis.

Expression of interleukin-33 and its receptor ST2 in periapical granulomas and radicular cysts.

Science.gov (United States)

Velickovic, Milena; Pejnovic, Nada; Petrovic, Renata; Mitrovic, Slobodanka; Jeftic, Ilija; Kanjevac, Tatjana; Lukic, Aleksandra

2016-01-01

Interleukin-33 (IL-33) is a recently identified cytokine belonging to the IL-1 family and ligand for the IL-1 receptor-related protein ST2. IL-33/ST2 signaling plays a critical role in allergy, autoimmunity, and chronic inflammatory disorders, but its role in the pathogenesis of periapical lesions is unknown. We aimed to investigate the expression patterns of IL-33 and ST2 in human periapical lesions. Periapical lesions (n = 36) and healthy periapical tissues (n = 10) were evaluated by immunohistochemistry using antibodies specific for human IL-33 and ST2. Lesion samples were further analyzed by double immunofluorescence to assess IL-33/ST2 co-expression. The numbers of IL-33- and ST2-positive fibroblasts were significantly higher in periapical lesions compared to healthy periapical tissues (both P 0.05). There were no significant differences in the numbers of IL-33- and ST2-positive fibroblasts and endothelial cells between periapical granulomas and radicular cysts (all P > 0.05). Similarly, numbers of ST2-positive mononuclear cells did not differ between periapical granulomas and radicular cysts (P > 0.05). The majority of epithelial cells in radicular cysts were IL-33 positive, while the small proportion of epithelial cells was ST2 positive. Double immunofluorescence analysis revealed IL-33/ST2 co-expression in fibroblasts and endothelial cells. IL-33 and ST2 are expressed in periapical granulomas and radicular cysts. Increased numbers of IL-33- and ST2-positive fibroblasts in periapical lesions when compared to healthy periapical tissues suggest that IL-33/ST2 signaling may be involved in periapical inflammation and tissue fibrosis. © 2015 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

77 FR 32391 - Building a 21st Century Digital Government

Science.gov (United States)

2012-06-01

... of May 23, 2012 Building a 21st Century Digital Government Memorandum for the Heads of Executive... century digital Government that delivers better digital services to the American people. Today, the CIO is releasing that strategy, entitled ``Digital Government: Building a 21st Century Platform to Better Serve the...

Army Research Laboratory S&T Campaign Plans 2015-2035

Science.gov (United States)

2014-09-01

for micro-robotics, and high quality factor communications, electronic warfare. Efforts focus on the maturation of LEAD zirconium titanate ( PZT ) and...spectrums (multiple impact, high energy impact, and high to low cycle fatigue ) to meet the needs of current and future Army platforms and structures...MATERIALS RESEARCH CAMPAIGN’s Polymer Coatings S&T Footprint S&T AREA POSTURE Polymer Coatings LEAD Corrosion & Fatigue research explores corrosion

Audiovisuaalinen koulutuspaketti ensihoitohenkilöstölle peruselintoimintojen mittaamisesta

OpenAIRE

Pelkonen, Juha

2013-01-01

Tiivistelmä Tämä opinnäyteyö oli kehittämistyö, jonka tarkoituksena oli laatia audiovisuaalinen koulutuspaketti peruselintoimintojen mittaamisesta Pohjois-Savon pelastuslaitokselle ensihoitohenkilöstölle. Kehittämistyön tavoitteena oli vahvistaa pelastuslaitoksen ensihoitohenkilöstön osaamista peruselintoimintojen mittaamisessa. Koulutuspaketin tavoitteena oli antaa vaihtoehtoinen tapa kerrata jo vanhaa opittua sekä motivoida uuteen oppimiseen audiovisuaalisesti demonstraati...

Construction: first of St. Lucie unit 2 successes

International Nuclear Information System (INIS)

Conway, W.F.

1989-01-01

The Nuclear Regulatory Commission (NRC) granted a full power operating license for St. Lucie Unit 2 on June 10, 1983, just six years after construction began. The industry average for nuclear power plant construction during this time was approximately ten years. The rate of completion had a positive effect on the cost of the facility. The price of the unit was $1.42 billion as compared to the $2 billion to $5 billion range experienced by other utilities for nuclear plants. These accomplishments were not serendipitous but the results of management techniques and personnel attitudes involved in the construction of the unit. More importantly, many of these same techniques and attitudes have now become part of a quality improvement program at St Lucie and are reflected in its performance indicators. This paper analyzes the construction success of St Lucie Unit 2 and demonstrates that excellent performance in the construction phase can be carried over to the operation of a facility

Advanced ST plasma scenario simulations for NSTX

International Nuclear Information System (INIS)

Kessel, C.E.; Synakowski, E.J.; Gates, D.A.; Kaye, S.M.; Menard, J.; Phillips, C.K.; Taylor, G.; Wilson, R.; Harvey, R.W.; Mau, T.K.

2005-01-01

Integrated scenario simulations are done for NSTX that address four primary milestones for developing advanced ST configurations: high β and high β N inductive discharges to study all aspects of ST physics in the high beta regime; non-inductively sustained discharges for flattop times greater than the skin time to study the various current drive techniques; non-inductively sustained discharges at high βfor flattop times much greater than a skin time which provides the integrated advanced ST target for NSTX; and non-solenoidal startup and plasma current rampup. The simulations done here use the Tokamak Simulation Code (TSC) and are based on a discharge 109070. TRANSP analysis of the discharge provided the thermal diffusivities for electrons and ions, the neutral beam (NB) deposition profile and other characteristics. CURRAY is used to calculate the High Harmonic Fast Wave (HHFW) heating depositions and current drive. GENRAY/CQL3D is used to establish the heating and CD deposition profiles for electron Bernstein waves (EBW). Analysis of the ideal MHD stability is done with JSOLVER, BALMSC, and PEST2. The simulations indicate that the integrated advanced ST plasma is reachable, obtaining stable plasmas with β ∼ 40% at β N 's of 7.7-9, I P = 1.0 MA and B T = 0.35 T. The plasma is 100% non-inductive and has a flattop of 4 skin times. The resulting global energy confinement corresponds to a multiplier of H 98(y,2 ) = 1.5. The simulations have demonstrated the importance of HHFW heating and CD, EBW off-axis CD, strong plasma shaping, density control, and early heating/H-mode transition for producing and optimizing these plasma configurations (author)

National Dam Safety Program. Eaton Dam (MO 31163), Mississippi - Kaskaskia - St. Louis Basin, St. Francois County, Missouri. Phase I Inspection Report.

Science.gov (United States)

1981-04-01

located near the north end of the Simms Mountain Fault System. The site is actually within this system which is about 5 mi wide and 40 mi long, in a...oLegon I V Roubidoux Formation u aleA "Z.Gasconade Dolomite Gunter Sandstone Member Of Eminence Dolomite m~neY, jrk-Potosi Dolomite Derby-Doerufl...westnMsoui Vow" Lamotte Sandstone Diabese (dikes and sills) St. Francois Mountains Intrusive Suite St. Francois Mountains Volcanic Supergiroup 0 10 20

Oliver St John Gogarty.

Science.gov (United States)

Clarke, R W

1997-01-01

Oliver St John Gogarty--Otolaryngologist to fashionable Edwardian Dublin--was a distinguished poet and a Senator in the fledgling Irish Free State after its establishment in 1922. He numbered amongst his acquaintances the poet William Butler Yeats, the novelist James Joyce and a host of political and literary persona who helped to shape modern Ireland. He was satirised as 'stately plump Buck Mulligan' in Joyce's novel Ulysses.

Smart Social Networking: 21st Century Teaching and Learning Skills

Science.gov (United States)

Boholano, Helen B.

2017-01-01

Education in the 21st century highlights globalization and internationalization. Pre-service teachers in the 21st century are technology savvy. To effectively engage and teach generation Z students, preservice teachers will help the educational system meet this requirement. The educational systems must be outfitted with a prerequisite of ICT…

Imaging QRS complex and ST segment in myocardial infarction

DEFF Research Database (Denmark)

Bacharova, Ljuba; Bang, Lia E; Szathmary, Vavrinec

2014-01-01

BACKGROUND: Acute myocardial infarction creates regions of altered electrical properties of myocardium resulting in typical QRS patterns (pathological Q waves) and ST segment deviations observed in leads related to the MI location. The aim of this study was to present a graphical method for imaging...... the changes in the sequence of depolarization and the ST segment deviations in myocardial infarction using the Dipolar ElectroCARdioTOpography (DECARTO) method. MATERIAL AND METHODS: Simulated ECG data corresponding to intramural, electrically inactive areas encircled by transmural areas with slowed impulse...... propagation velocity in anteroseptal and inferior locations were used for imaging the altered sequence of depolarization and the ST vector. The ECGs were transformed to areas projected on the image surface so as to image the process of ventricular depolarization based on the orientation and magnitude...

76 FR 30018 - Safety Zone; Marysville Days Fireworks, St. Clair River, Marysville, MI

Science.gov (United States)

2011-05-24

...-AA00 Safety Zone; Marysville Days Fireworks, St. Clair River, Marysville, MI AGENCY: Coast Guard, DHS. ACTION: Temporary final rule. SUMMARY: The Coast Guard is establishing a temporary safety zone on St. Clair River, Marysville, MI. This zone is intended to restrict vessels from a portion of St. Clair River...

77 FR 29901 - Safety Zone; Marysville Days Fireworks, St. Clair River, Marysville, MI

Science.gov (United States)

2012-05-21

...-AA00 Safety Zone; Marysville Days Fireworks, St. Clair River, Marysville, MI AGENCY: Coast Guard, DHS. ACTION: Temporary final rule. SUMMARY: The Coast Guard is establishing a temporary safety zone on the St. Clair River, Marysville, Michigan. This zone is intended to restrict vessels from a portion of the St...

St. John le calviniste, ou l’émule de Gil-Martin Charlotte Brontë’s Calvinist St. John Emulating James Hogg’s Gil-Martin

Directory of Open Access Journals (Sweden)

Jean Berton

2009-07-01

Full Text Available This article aims to show how far Hogg’s archetypal character, Gil-Martin, influenced Charlotte Brontë’s enigmatic character, St. John, who appears in chapters XXVI to XXXV and is mentioned again in the conclusion of Jane Eyre. Some unexpected words, like “glen”, in a greater Yorkshire area, operate as keywords to a “deep context” study in a neo-contextualist approach. Even though St. John cannot be mistaken for a double of Gil-Martin, a fair number of details tend to prove that James Hogg’s Private Memoirs and Confessions of a Justified Sinner deeply influenced Charlotte Brontë—both pride-driven St. John and Gil-Martin stand for demonic despotism. Yet, if Gil-Martin is a straightforward Gothic illustration of Satan, St. John is a reincarnation of a marble-cold Apollo in a dogma-trapped Calvinist. Brontë’s intention was not so much to denounce noxious excesses in religious beliefs as to set her heroine’s wise independence against nefarious male domination: whereas victimised Robert Wringhim is driven to despair and suicide, self-reliant Jane Eyre escapes from St. John’s grip. In both narratives relationships between men and women are shown as tragically warped by religious behavioural extravagance, but only the female character is granted a positive outcome to serve an optimistic view on life: Robert Wringhim is violently wrung out of the society of men and women, St. John Rivers, from “Marsh End”, blindly drifts away to his death in India, and airy Jane, of “Moor House”, wafts away to anchor to Edward Rochester, the sender of the airwave-born call.

Differentiating ST elevation myocardial infarction and nonischemic causes of ST elevation by analyzing the presenting electrocardiogram

DEFF Research Database (Denmark)

Jayroe, Jason B; Spodick, David H; Nikus, Kjell

2008-01-01

Guidelines recommend that patients with suggestive symptoms of myocardial ischemia and ST-segment elevation (STE) in > or =2 adjacent electrocardiographic leads should receive immediate reperfusion therapy. Novel strategies aimed to reduce door-to-balloon time, such as prehospital wireless...

ST ECS error handling and detector safety

CERN Document Server

Esperante Pereira, D

2010-01-01

This note describes the automatic operation sequences that the ECS implements in order to operate the ST detector in a safe and reliable way. First, the start-up sequences to set the detector in a well known state are described. In addition the possible ST detector states based on the status of the different detector elements will be defined. The states are of crucial interest for the safe operation of the detector when the LHC beam is ready. Besides, the ECS automatic actions taken in case of abnormal status of any of the detector elements are reported. Next, the operational alarm ranges and the error recovery mechanisms are mentioned.

Unintended and unwanted pregnancy in St. Lucia.

Science.gov (United States)

Denton, A B; Chase, W M; Scott, K

1994-09-01

Among 200 mothers interviewed in St. Lucia, 82.5% described their pregnancy as unintended and 44% as unwanted; 80% of women having an intended pregnancy and 94.6% having an unintended pregnancy were unmarried and 18.5% were teenagers. Mothers of unintended pregnancies were significantly younger, were of significantly higher parity and had begun sexual relations at a significantly earlier age than mothers of intended pregnancies; and, unlike mothers of planned pregnancies, their desired interpregnancy interval was significantly longer than the actual interval. These results and the sporadic and ineffective use of contraception in St. Lucia emphasize the need for improvements in fertility regulation in that country.

ST/EL and ST/CV services for TI2 & TI8 LHC injection tunnels

CERN Document Server

Akhtar, S; CERN. Geneva. ST Division

2002-01-01

This paper describes the ST/EL and ST/CV services for TI2 & TI8 LHC injection tunnels. The cooling and ventilation part describes the requirements for design and installation of more than 10 km of pipeline that is going to be laid down in the tunnels. Main operating parameters as well as manufacture procedures are explained. Preliminary work schedule with the cost estimate is also presented. Electrical power will be distributed from the LHC side and the SPS side for the machine and the general services. All power converters will be installed on surface buildings. The link between the main bend converters and the main bend magnets will be realised with water-cooled cables. Rest of the magnets will be cabled by using conventional copper and aluminium cables. Due to long lengths of the injection tunnels a dry 18kV transformer will be installed in TJ8 to serve the general services for TI8. The same will apply to TI2 by installing a transformer at the bottom of the PMI2 shaft.

Novos sinônimos e uma nova combinação em Pusillanthus (Loranthaceae New synonyms and a new combination in Pusillanthus (Loranthaceae

Directory of Open Access Journals (Sweden)

Claudenir Simões Caires

2012-09-01

Full Text Available Uma revisão de Pusillanthus Kuijt para o Brasil é apresentada. O gênero monotípico recém-descrito ocorre na Venezuela, Guiana e Brasil. No Brasil, distribui-se somente na Caatinga, nos estados de Alagoas, Bahia e Paraíba. A nova combinação Pusillanthus pubescens (Rizzini Caires é proposta e as espécies Phthirusa caatingae Rizzini, Pusillanthus trichodes (Rizzini Kuijt e Struthanthus pubescens var. bahiensis Rizzini são tratadas como seus sinônimos taxonômicos. Uma prancha ilustrativa e um mapa de distribuição para o gênero no Brasil são apresentados, bem como estudos da arquitetura foliar, de superfícies de caule, folha e grãos de pólen usando Microscopia Eletrônica de Varredura.A revision of Pusillanthus Kuijt for Brazil is presented. The recently described monotypic genus occurs in Venezuela, Guyana, and Brazil. In Brazil, it is distributed only within the Caatinga domain, in the states of Alagoas, Bahia and Paraíba. The new combination Pusillanthus pubescens (Rizzini Caires is proposed and the species Phthirusa caatingae Rizzini, Pusillanthus trichodes (Rizzini Kuijt, and Struthanthus pubescens var. bahiensis Rizzini are treated as its taxonomic synonyms. An illustrative plate and a distribution map for the genus in Brazil are presented, as well as information about leaf architecture, and stem, leaf, and pollen grain surfaces (based on scanning electron microscopy.

File list: ALL.Lar.10.AllAg.1st_instar [Chip-atlas[Archive

Lifescience Database Archive (English)

Full Text Available ALL.Lar.10.AllAg.1st_instar dm3 All antigens Larvae 1st instar SRX013088,SRX013064,...SRX013044,SRX013009,SRX013072,SRX013097,SRX013055,SRX013056 http://dbarchive.biosciencedbc.jp/kyushu-u/dm3/assembled/ALL.Lar.10.AllAg.1st_instar.bed ...

File list: ALL.Lar.50.AllAg.1st_instar [Chip-atlas[Archive

Lifescience Database Archive (English)

Full Text Available ALL.Lar.50.AllAg.1st_instar dm3 All antigens Larvae 1st instar SRX013009,SRX013072,...SRX013088,SRX013044,SRX013064,SRX013097,SRX013056,SRX013055 http://dbarchive.biosciencedbc.jp/kyushu-u/dm3/assembled/ALL.Lar.50.AllAg.1st_instar.bed ...

File list: ALL.Lar.20.AllAg.1st_instar [Chip-atlas[Archive

Lifescience Database Archive (English)

Full Text Available ALL.Lar.20.AllAg.1st_instar dm3 All antigens Larvae 1st instar SRX013009,SRX013072,...SRX013088,SRX013044,SRX013064,SRX013097,SRX013055,SRX013056 http://dbarchive.biosciencedbc.jp/kyushu-u/dm3/assembled/ALL.Lar.20.AllAg.1st_instar.bed ...

File list: ALL.Lar.05.AllAg.1st_instar [Chip-atlas[Archive

Lifescience Database Archive (English)

Full Text Available ALL.Lar.05.AllAg.1st_instar dm3 All antigens Larvae 1st instar SRX013088,SRX013009,...SRX013064,SRX013044,SRX013072,SRX013055,SRX013097,SRX013056 http://dbarchive.biosciencedbc.jp/kyushu-u/dm3/assembled/ALL.Lar.05.AllAg.1st_instar.bed ...

Multiple protein biomarker assessment for recombinant bovine somatotropin (rbST abuse in cattle.

Directory of Open Access Journals (Sweden)

Susann K J Ludwig

Full Text Available Biomarker profiling, as a rapid screening approach for detection of hormone abuse, requires well selected candidate biomarkers and a thorough in vivo biomarker evaluation as previously done for detection of growth hormone doping in athletes. The bovine equivalent of growth hormone, called recombinant bovine somatotropin (rbST is (illegally administered to enhance milk production in dairy cows. In this study, first a generic sample pre-treatment and 4-plex flow cytometric immunoassay (FCIA were developed for simultaneous measurement of four candidate biomarkers selected from literature: insulin-like growth factor 1 (IGF-1, its binding protein 2 (IGFBP2, osteocalcin and endogenously produced antibodies against rbST. Next, bovine serum samples from two extensive controlled rbST animal treatment studies were used for in vivo validation and biomarker evaluation. Finally, advanced statistic tools were tested for the assessment of biomarker combination quality aiming to correctly identify rbST-treated animals. The statistical prediction tool k-nearest neighbours using a combination of the biomarkers osteocalcin and endogenously produced antibodies against rbST proved to be very reliable and correctly predicted 95% of the treated samples starting from the second rbST injection until the end of the treatment period and even thereafter. With the same biomarker combination, only 12% of untreated animals appeared false-positive. This reliability meets the requirements of Commission Decision 2002/657/EC for screening methods in veterinary control. From the results of this multidisciplinary study, it is concluded that the osteocalcin - anti-rbST-antibodies combination represent fit-for-purpose biomarkers for screening of rbST abuse in dairy cattle and can be reliably measured in both the developed 4-plex FCIA as well as in a cost-effective 2-plex microsphere-based binding assay. This screening method can be incorporated in routine veterinary monitoring

Postcolonial Identity Politics, Language and the Schools in St. Lucia

Science.gov (United States)

St. Hilaire, Aonghas

2009-01-01

In the postcolonial era, a cultural nationalist movement has sought to elevate the status of St. Lucia's creole vernacular, Kweyol, and with some success--it is now the most visible symbol of St. Lucian national identity. This relatively new development has altered somewhat the historic linguistic status quo between the official, high status…

Hydrologic data summary for the St. Lucie River Estuary, Martin and St. Lucie Counties, Florida, 1998-2001

Science.gov (United States)

Byrne, Michael J.; Patino, Eduardo

2004-01-01

A hydrologic analysis was made at three canal sites and four tidal sites along the St. Lucie River Estuary in southeastern Florida from 1998 to 2001. The data included for analysis are stage, 15-minute flow, salinity, water temperature, turbidity, and suspended-solids concentration. During the period of record, the estuary experienced a drought, major storm events, and high-water discharge from Lake Okeechobee. Flow mainly occurred through the South Fork of the St. Lucie River; however, when flow increased through control structures along the C-23 and C-24 Canals, the North Fork was a larger than usual contributor of total freshwater inflow to the estuary. At one tidal site (Steele Point), the majority of flow was southward toward the St. Lucie Inlet; at a second tidal site (Indian River Bridge), the majority of flow was northward into the Indian River Lagoon. Large-volume stormwater discharge events greatly affected the St. Lucie River Estuary. Increased discharge typically was accompanied by salinity decreases that resulted in water becoming and remaining fresh throughout the estuary until the discharge events ended. Salinity in the estuary usually returned to prestorm levels within a few days after the events. Turbidity decreased and salinity began to increase almost immediately when the gates at the control structures closed. Salinity ranged from less than 1 to greater than 35 parts per thousand during the period of record (1998-2001), and typically varied by several parts per thousand during a tidal cycle. Suspended-solids concentrations were observed at one canal site (S-80) and two tidal sites (Speedy Point and Steele Point) during a discharge event in April and May 2000. Results suggest that most deposition of suspended-solids concentration occurs between S-80 and Speedy Point. The turbidity data collected also support this interpretation. The ratio of inorganic to organic suspended-solids concentration observed at S-80, Speedy Point, and Steele Point

IDENTIFIKASI SURFAKTIN PADA PSEUDOMONAS FLUORESCENS ST1 PENGENDALI EFEKTIF PENYAKIT PUSTUL KEDELAI

Directory of Open Access Journals (Sweden)

Suskandini Ratih Dirmawati .

2011-11-01

Full Text Available Identification of surfactin in Pseudomonas fluorescens ST1 which effectively suppres soybean bacterial pustule.   Identification of surfactin in Pseudomonas fluorescens ST1 filtrate was conducted in Plant Pest and Disease Laboratory, Bogor Agriculture University.  The 48 hours cultured suspension of  P. fluorescens ST1 with 108 CFU/ml density was centrifuged to obtain the supernatant.  The supernatant was analyzed for its surfactin content by High Performance Liquid Chromatography with Colum ODS-5 and eluen acetonitril and acetat acid.  The result showed  that  surfactin was producted by P. fluorescens ST1 and this bioactive substance could suppres the bacterial pustule on soybean.

Penaeid prawns in the St Lucia Lake System: Post-larval recruitment ...

African Journals Online (AJOL)

Penaeid prawns in the St Lucia Lake System: Post-larval recruitment and the bait fishery. ... Recruitment of post-larval penaeid prawns and the bait prawn fishery in the St Lucia Lake System were monitored for ... AJOL African Journals Online.

Immunogenicity of nuclear-encoded LTB:ST fusion protein from Escherichia coli expressed in tobacco plants.

Science.gov (United States)

Rosales-Mendoza, Sergio; Soria-Guerra, Ruth E; Moreno-Fierros, Leticia; Govea-Alonso, Dania O; Herrera-Díaz, Areli; Korban, Schuyler S; Alpuche-Solís, Ángel G

2011-06-01

Enterotoxigenic Escherichia coli (ETEC) is one of the main causative agents of diarrhea in infants and for travelers. Inclusion of a heat-stable (ST) toxin into vaccine formulations is mandatory as most ETEC strains can produce both heat-labile (LT) and ST enterotoxins. In this study, a genetic fusion gene encoding for an LTB:ST protein has been constructed and transferred into tobacco via Agrobacterium tumefaciens-mediated transformation. Transgenic tobacco plants carrying the LTB:ST gene are then subjected to GM1-ELISA revealing that the LTB:ST has assembled into pentamers and displays antigenic determinants from both LTB and ST. Protein accumulation of up to 0.05% total soluble protein is detected. Subsequently, mucosal and systemic humoral responses are elicited in mice orally dosed with transgenic tobacco leaves. This has suggested that the plant-derived LTB:ST is immunogenic via the oral route. These findings are critical for the development of a plant-based vaccine capable of eliciting broader protection against ETEC and targeting both LTB and ST. Features of this platform in comparison to transplastomic approaches are discussed.

Analysis and reconstructed modelling of the debris flow event of the 21st of July 2012 of St. Lorenzen (Styria, Austira)

Science.gov (United States)

Janu, Stefan; Mehlhorn, Susanne; Moser, Markus

2013-04-01

Analysis and reconstructed modelling of the debris flow event of the 21st of July 2012 of St. Lorenzen (Styria, Austria) Authors: Stefan Janu, Susanne Mehlhorn, Markus Moser The village of St. Lorenzen, in the Styrian Palten valley is situated on the banks of the Lorenz torrent, in which a debris flow event occurred in the early morning hours of the 21st of July 2012, causing catastrophic damage to residential buildings and other infrastructural facilities. In the ministry-approved hazard zone map of 2009, the flood water discharge and bedload volume associated with a 150-year event was estimated at 34 m³/s and 25,000 m³ respectively for the 5.84 km² catchment area. The bedload transport capacity of the torrent was classified as ranging from 'heavy' to 'capable of producing debris flows'. The dominant process type of the mass movement event may be described as a fine-grained debris flow. The damage in the residential area of St.Lorenzen was caused by a debris flow pulse in the lower reach of the Lorenz torrent. This debris flow pulse was in turn caused by numerous landslides along the middle reaches of the torrent, some of which caused blockages, ultimately leading to an outburst event in the main torrent. Discharge cross-sections ranging from 65 - 90 m², and over 100 m² in a few instances, were measured upstream of the St. Lorenzen residential area. Back-calculations of velocities yielded an average debris flow velocity along the middle reaches of the torrent between 11 and 16 m/s. An average velocity of 9 m/s was calculated for the debris flow at the neck of the alluvial fan directly behind the center of the village. Due to both the high discharge values as well as to the height of the mass movement deposits, the natural hazard event of 21 July 2012 in St. Lorenzen is clearly to be described as having had an extreme intensity. A total of 67 buildings were damaged along the Lorenz torrent, 7 of were completely destroyed. According to the Austrian Service for

A 3000 yr paleostorm record from St. Catherines Island, Georgia

Science.gov (United States)

Braun, Erick; Meyer, Brian; Deocampo, Daniel; Kiage, Lawrence M.

2017-09-01

Tropical cyclones (hurricanes in the northern hemisphere) are amongst the most devastating of the world's natural disasters and cause billions of dollars in damage every year. Data on the likelihood of a coastal site being struck by a major hurricane strike can potentially aid in planning and mitigation efforts that could save money and lives. However, forecasting requires data that are currently insufficient for the Georgia Bight. This study provides information to enhance the paleohurricane record by analysis of a 467 cm thick vibracore raised from St. Catherines Island, GA. Sediment geochemistry and foraminiferal assemblages indicate deposits attributable to seven paleohurricane events, five of which were likely major hurricanes when they made landfall on St. Catherines. Magnitudes were estimated by comparison to the overwash deposit left by ;The Sea Islands hurricane of 1893;, a major hurricane recorded by the recent sediment of St. Catherines Island. The St. Catherines record also shows a change in the activity levels on the Georgia coast with two distinct activity regimes over the past 3000 years.

RESTAURANT AND CAFETERIA SERVICES ARRANGEMENTS FOR MAY 1ST, 2001

CERN Multimedia

Restaurant Supervisory Committee

2001-01-01

1. Restaurants As Tuesday, May 1st, is an official CERN holiday, restaurants no 2 (DSR : Bldg. 504 - Meyrin) and no 3 (Avenance : Bldg. 866 - Prévessin) will be closed as from Monday, April 30 at 18h00. They will reopen on Wednesday, May 2nd at 6h30 (rest. no 2) and at 7h00 (rest. no 3). On May 1st, a limited service will be provided by restaurant no. 1 (COOP : Bldg. 501 - Meyrin) from 8h00 to 21h00 with hot meals served from 11h30 to 14h00 and from 18h00 to 19h30. 2. Satellite cafétérias All satellite cafétérias will be closed on May 1st. They will all operate normally on Monday, April 30, except for buildings 17 (Meyrin), 865 and 892 (Prévessin) which will be closed. 3. Newspaper stand The newspaper kiosque in building 501 will be closed on May 1st.

Advanced ST Plasma Scenario Simulations for NSTX

International Nuclear Information System (INIS)

Kessel, C.E.; Synakowski, E.J.; Gates, D.A.; Harvey, R.W.; Kaye, S.M.; Mau, T.K.; Menard, J.; Phillips, C.K.; Taylor, G.; Wilson, R.

2004-01-01

Integrated scenario simulations are done for NSTX [National Spherical Torus Experiment] that address four primary milestones for developing advanced ST configurations: high β and high β N inductive discharges to study all aspects of ST physics in the high-beta regime; non-inductively sustained discharges for flattop times greater than the skin time to study the various current-drive techniques; non-inductively sustained discharges at high β for flattop times much greater than a skin time which provides the integrated advanced ST target for NSTX; and non-solenoidal start-up and plasma current ramp-up. The simulations done here use the Tokamak Simulation Code (TSC) and are based on a discharge 109070. TRANSP analysis of the discharge provided the thermal diffusivities for electrons and ions, the neutral-beam (NB) deposition profile, and other characteristics. CURRAY is used to calculate the High Harmonic Fast Wave (HHFW) heating depositions and current drive. GENRAY/CQL3D is used to establish the heating and CD [current drive] deposition profiles for electron Bernstein waves (EBW). Analysis of the ideal-MHD stability is done with JSOLVER, BALMSC, and PEST2. The simulations indicate that the integrated advanced ST plasma is reachable, obtaining stable plasmas with β ∼ 40% at β N 's of 7.7-9, I P = 1.0 MA, and B T = 0.35 T. The plasma is 100% non-inductive and has a flattop of 4 skin times. The resulting global energy confinement corresponds to a multiplier of H 98(y,2) 1.5. The simulations have demonstrated the importance of HHFW heating and CD, EBW off-axis CD, strong plasma shaping, density control, and early heating/H-mode transition for producing and optimizing these plasma configurations

A Correction Formula for the ST Segment Measurements for the AC-coupled Electrocardiograms

DEFF Research Database (Denmark)

Schmid, Ramun; Isaksen, Jonas; Leber, Remo

2017-01-01

Goal: The ST segment of an electrocardiogram (ECG) is very important for the correct diagnosis of an acute myocardial infarction. Most clinical ECGs are recorded using an AC-coupled ECG amplifier. It is well known, that first-order high-pass filters used for the AC coupling can affect the ST...... segment of an ECG. This effect is stronger the higher the filter's cut-off frequency is and the larger the QRS integral is. We present a formula that estimates these changes in the ST segment and therefore allows for correcting ST measurements that are based on an AC-coupled ECG. Methods: The presented...

[Treatment and management after acute coronary syndrome without ST-elevation].

Science.gov (United States)

Drogoul, Laurent; Scarlatti, Didier; Ferrari, Emile

2010-03-01

Coronary syndromes without ST elevation, previously known as unstable angina, are now more frequent than ST elevation myocardial infarction. Evidence-based studies should guide their management after hospital discharge. This management seeks to fulfill precise objectives and has been demonstrated to be effective in terms of survival. Copyright (c) 2009 Elsevier Masson SAS. All rights reserved.

Flora of St Katherine Protectorate: key to families and genera ...

African Journals Online (AJOL)

An illustrated key to families and genera of the flora of the St Katherine Protectorate is provided to facilitate the identification of the unique flora of the area, based on five years of collecting mainly in the mountains and wadis surrounding the town of St Katherine. The key includes 43 families and 141 genera, the families ...

Transformations in Air Transportation Systems For the 21st Century

Science.gov (United States)

Holmes, Bruce J.

2004-01-01

Globally, our transportation systems face increasingly discomforting realities: certain of the legacy air and ground infrastructures of the 20th century will not satisfy our 21st century mobility needs. The consequence of inaction is diminished quality of life and economic opportunity for those nations unable to transform from the 20th to 21st century systems. Clearly, new thinking is required regarding business models that cater to consumers value of time, airspace architectures that enable those new business models, and technology strategies for innovating at the system-of-networks level. This lecture proposes a structured way of thinking about transformation from the legacy systems of the 20th century toward new systems for the 21st century. The comparison and contrast between the legacy systems of the 20th century and the transformed systems of the 21st century provides insights into the structure of transformation of air transportation. Where the legacy systems tend to be analog (versus digital), centralized (versus distributed), and scheduled (versus on-demand) for example, transformed 21st century systems become capable of scalability through technological, business, and policy innovations. Where air mobility in our legacy systems of the 20th century brought economic opportunity and quality of life to large service markets, transformed air mobility of the 21st century becomes more equitable available to ever-thinner and widely distributed populations. Several technological developments in the traditional aircraft disciplines as well as in communication, navigation, surveillance and information systems create new foundations for 21st thinking about air transportation. One of the technological developments of importance arises from complexity science and modern network theory. Scale-free (i.e., scalable) networks represent a promising concept space for modeling airspace system architectures, and for assessing network performance in terms of robustness

StAR Enhances Transcription of Genes Encoding the Mitochondrial Proteases Involved in Its Own Degradation

Science.gov (United States)

Bahat, Assaf; Perlberg, Shira; Melamed-Book, Naomi; Lauria, Ines; Langer, Thomas

2014-01-01

Steroidogenic acute regulatory protein (StAR) is essential for steroid hormone synthesis in the adrenal cortex and the gonads. StAR activity facilitates the supply of cholesterol substrate into the inner mitochondrial membranes where conversion of the sterol to a steroid is catalyzed. Mitochondrial import terminates the cholesterol mobilization activity of StAR and leads to mounting accumulation of StAR in the mitochondrial matrix. Our studies suggest that to prevent mitochondrial impairment, StAR proteolysis is executed by at least 2 mitochondrial proteases, ie, the matrix LON protease and the inner membrane complexes of the metalloproteases AFG3L2 and AFG3L2:SPG7/paraplegin. Gonadotropin administration to prepubertal rats stimulated ovarian follicular development associated with increased expression of the mitochondrial protein quality control system. In addition, enrichment of LON and AFG3L2 is evident in StAR-expressing ovarian cells examined by confocal microscopy. Furthermore, reporter studies of the protease promoters examined in the heterologous cell model suggest that StAR expression stimulates up to a 3.5-fold increase in the protease gene transcription. Such effects are StAR-specific, are independent of StAR activity, and failed to occur upon expression of StAR mutants that do not enter the matrix. Taken together, the results of this study suggest the presence of a novel regulatory loop, whereby acute accumulation of an apparent nuisance protein in the matrix provokes a mitochondria to nucleus signaling that, in turn, activates selected transcription of genes encoding the enrichment of mitochondrial proteases relevant for enhanced clearance of StAR. PMID:24422629

St 2-22 - Another Symbiotic Star with High-Velocity Bipolar Jets

Science.gov (United States)

Tomov, T.; Zamanov, R.; Gałan, C.; Pietrukowicz, P.

2017-09-01

We report the detection of high-velocity components in the wings of Hα emission line in spectra of symbiotic binary star St 2-22 obtained in 2005. This finding encouraged us to start the present investigation in order to show that this poorly-studied object is a jet-producing system. We have used high-resolution optical and low-resolution near-infrared spectra, as well as available optical and infrared photometry, to evaluate some physical parameters of the St 2-22 components and characteristics of the jets. We confirm that St 2-22 is a S-type symbiotic star. Our results demonstrate that an unnoticed outburst, similar to those in classical symbiotic systems, occurred in the first half of 2005. During the outburst, collimated bipolar jets were ejected by the hot component of St 2-22 with an average velocity of about 1700 km/s.

Biometria de frutos e sementes e emergência de plântulas de duas espécies frutíferas do gênero Campomanesia

Directory of Open Access Journals (Sweden)

Michele Camargo de Oliveira

2011-06-01

Full Text Available As espécies Campomanesia adamantium e Campomanesia pubescens são morfologicamente semelhantes, ocorrem em ambientes comuns do Bioma Cerrado, por isso são difíceis de serem separadas e identificadas. Os objetivos foram analisar dados biométricos de frutos e sementes de C. adamantium e de C. pubescens, além do processo de emergência das plântulas, para fins de comparações entre as espécies. Em novembro de 2007, de 50 frutos de cada espécie, foram realizadas medidas do comprimento transversal (mm e longitudinal (mm dos frutos e das sementes, massa da matéria fresca dos frutos (g, número de lóculos por fruto e número de lóculos com sementes. Para o teste de emergência, dois experimentos independentes, um para cada espécie, foram instalados em delineamento inteiramente casualizado, com seis métodos de beneficiamento dos frutos para remoção, secagem ou lavagem da mucilagem e quatro repetições com 40 sementes por parcela. Com frutos mais volumosos, com maior acúmulo de massa fresca e maior amplitude biométrica em relação aos de C. pubescens, C. adamantium apresenta potencial para seleção de materiais promissores para fins de melhoramento. A secagem à sombra por 24 horas das sementes com mucilagem reduz os percentuais de emergência e de plântulas normais, além da velocidade de emergência de plântulas de C. adamantium, embora este método seja indiferente para plântulas de C. pubescens. Sob as mesmas condições experimentais, plântulas de C. pubescens apresentam maior capacidade de emergência e de plântulas normais, além de maiores frequências diárias de plântulas emersas e redução dos tempos de emergência em relação às plântulas de C. adamantium.

Karvian seurakunnan henkilöstötilinpäätös

OpenAIRE

Vaskela, Soila

2008-01-01

Tässä opinnäytetyössä tutkittiin yleisesti sekä käytännössä henkilöstötilinpäätöksen tarkoitusta ja sisältöä. Kohdeorganisaation eli Karvian seurakunnan avulla rakennettiin käytännön esimerkki seurakunnan ensimmäisestä henkilöstötilinpäätöksestä. Tutkimuksen tavoitteena oli löytää oikeat ratkaisut henkilöstötilinpäätöksen rakentamiseen organisaatiossa, jossa kyseinen asiakirja ei vielä ole tunnettu. Lisäksi tavoitteena oli laatia seurakunnalle käyttökelpoinen henkilöstötilinpäätösmalli, jota ...

Drinking games and contextual factors of 21st birthday drinking.

Science.gov (United States)

Neighbors, Clayton; Rodriguez, Lindsey M; Rinker, Dipali V; DiBello, Angelo M; Young, Chelsie M; Chen, Chun-Han

2014-09-01

21st birthday celebrations are among the highest risks for alcohol use throughout emerging adulthood and celebrants often experience a range of alcohol-related consequences. The present research considered what happens when drinking games are paired with an already high-risk event (i.e., 21st birthday celebrations) and how drinking games compare with other contextual factors on 21st birthdays. Approximately four days after turning 21, 1124 college students (55% women) completed an online survey assessing alcohol use and related consequences experienced during their birthday celebrations. Participants were also asked whether drinking games and other contextual factors were associated with their celebrations. Overall, 18% of participants reported playing drinking games during their 21st birthday celebrations. These individuals reported consuming more alcohol, had higher estimated BACs, and experienced more negative consequences than those who did not play drinking games. The association between playing drinking games and alcohol use and negative consequences was stronger for men. The effect of drinking games on negative consequences was mediated through elevated BAC levels. Receiving bar specials, having drinks purchased, playing drinking games, and loud music were uniquely and significantly associated with all alcohol outcomes. Together, these results suggest that drinking games are part of a larger context of risk contributing to extreme drinking on 21st birthdays. Furthermore, these results will help to facilitate interventions that are more individually tailored to target specific contextual risks, behaviors, and events.

Responsiveness summary for the engineering evaluation/cost analysis for decontamination at the St. Louis Downtown Site, St. Louis, Missouri

International Nuclear Information System (INIS)

Picel, M.H.; Peterson, J.M.; Williams, M.J.

1991-12-01

The US Department of Energy (DOE) is responsible for conducting remedial actions at the Mallinckrodt Chemical Plant, also referred to as the St. Louis Downtown Site (SLDS), located in the city of St. Louis, Missouri. Remedial activities at the SLDS are being carried out under DOE's Formerly Utilized Sites Remedial Action Program (FUSRAP) as part of the overall cleanup planned for three noncontiguous areas in St. Louis, which are collectively referred to as the St. Louis Site. Potential response action alternatives for managing the contaminated material generated at the SLDS have been evaluated in accordance with US Environmental Protection Agency (EPA) guidance for conducting interim actions under the Comprehensive Environmental Response, Compensation, and Liability Act (CERCLA), as amended. An engineering evaluation/cost analysis (EE/CA) report was prepared to document this process. On the basis of the analysis presented in the EE/CA, the preferred alternative for the management of contaminated wastes generated by DOE-supported plant activities is the provision of temporary storage capacity, which can be made available by modifying an existing building (i.e., Building 116) at SLDS. This alternative would enable DOE and Mallinckrodt to coordinate efforts to prevent the uncontrolled relocation of contamination and ensure that ultimate site cleanup objectives are not complicated by plant activities implemented by Mallinckrodt. The EE/CA, dated May 1991, was issued to the general public on June 7, 1991, and a public comment period was held from June 7 through July 10, 1991, in accordance with the public participation process identified in CERCLA. Comments on the proposed action were received in writing from the Missouri Department of Health, private citizen Kay Drey, and the EPA Region 7. This responsiveness summary has been prepared to respond to issues identified in these comment letters on the proposed action

Promoting the 21st century scientific literacy skills through innovative chemistry instruction

Science.gov (United States)

Rahayu, Sri

2017-12-01

Students need to be equipped with the 21st century skills/capabilities to ensure their competitiveness in the knowledge era. So, it is imperative that education at school should be changed in order to fulfill the need. However, there is not any specified approach on how to educate young students for the 21st century capabilities. Regardless the impediment for ts exist, we need to construct an innovative instruction that can develop the students' 21st century skills by incorporating the skills needed, based on contemporary theory of learning, necessary context of learning and appropriate assessment in a chemistry subject matter. This paper discuss the feasible skills to be promoted through chemistry course. Those skills/capabilities are scientific literacy, higher order thinking, communicationand collaboration and curiosity. The promoted are called the 21st century scientific literacy skills in which it emphasis on scientific literacy and embedded the other 21st century skills into the innovative chemistry instruction. The elements involve in the instruction such as inquiry and constructivist approach, nature of science, contemporary/socioscientific issues, critical thinking (higher order thinking).

21ST-CENTURY TEACHERS: THE STUDENTS’ PERSPECTIVES

Directory of Open Access Journals (Sweden)

Maida Norahmi

2017-03-01

Full Text Available The issues regarding the demands of creative, innovative, and professional teachers are certainly on the concern of stakeholders and practitioners in education. Substantial efforts were conducted by the government to meet the 21st-century teachers having the four competencies required for being a teacher and coping with the needs of modern education. A survey research was conducted to collect respondents’ opinion as the main source of data to describe whether the 21st-century teachers are on the demands and to gain information that the students have a similar perception to teacher’s competencies required by the government. Seventy-five questionnaires related to the competencies were given to students of English Education Study Program of 2013 to 2016. The questionnaires were aimed at collecting written information dealing with what the students perceived towards the activities implemented by teachers in the process of teaching and learning. The result of questionnaire analysis revealed that most students expected the 21st-century teachers to have skills in teaching and in connecting it with the development of today’s technology and today’s student characteristics. The data also showed that the students constructed the same characteristics of teacher’s competencies required by the government regarding pedagogy, personality, sociality, and professionality.

Comparative Genomic Characterization of the Highly Persistent and Potentially Virulent Cronobacter sakazakii ST83, CC65 Strain H322 and Other ST83 Strains

Directory of Open Access Journals (Sweden)

Hannah R. Chase

2017-06-01

Full Text Available Cronobacter (C. sakazakii is an opportunistic pathogen and has been associated with serious infections with high mortality rates predominantly in pre-term, low-birth weight and/or immune compromised neonates and infants. Infections have been epidemiologically linked to consumption of intrinsically and extrinsically contaminated lots of reconstituted powdered infant formula (PIF, thus contamination of such products is a challenging task for the PIF producing industry. We present the draft genome of C. sakazakii H322, a highly persistent sequence type (ST 83, clonal complex (CC 65, serotype O:7 strain obtained from a batch of non-released contaminated PIF product. The presence of this strain in the production environment was traced back more than 4 years. Whole genome sequencing (WGS of this strain together with four more ST83 strains (PIF production environment-associated confirmed a high degree of sequence homology among four of the five strains. Phylogenetic analysis using microarray (MA and WGS data showed that the ST83 strains were highly phylogenetically related and MA showed that between 5 and 38 genes differed from one another in these strains. All strains possessed the pESA3-like virulence plasmid and one strain possessed a pESA2-like plasmid. In addition, a pCS1-like plasmid was also found. In order to assess the potential in vivo pathogenicity of the ST83 strains, each strain was subjected to infection studies using the recently developed zebrafish embryo model. Our results showed a high (90–100% zebrafish mortality rate for all of these strains, suggesting a high risk for infections and illness in neonates potentially exposed to PIF contaminated with ST83 C. sakazakii strains. In summary, virulent ST83, CC65, serotype CsakO:7 strains, though rarely found intrinsically in PIF, can persist within a PIF manufacturing facility for years and potentially pose significant quality assurance challenges to the PIF manufacturing industry.

Organisation des travaux ST-CV

CERN Document Server

Martel, C; CERN. Geneva. ST Division

2003-01-01

Débutée il y a deux ans, la phase de construction des installations de refroidissement du LHC a atteint en 2003 son apogée. De nombreux autres projets sont également gérés par le groupe dans divers secteurs du laboratoire. La spécificité du groupe est de réaliser des installations complexes impliquant des spécificités diverses telles qu’aéraulique, hydraulique, électrique, etc. Pour faire face à ces demandes la section travaux du groupe ST CV a adopté une structure capable de réaliser ces divers projets avec un minimum de personnel. La première partie de ce document décrit l’organisation de la section travaux ST CV. Dans une deuxième partie, les auteurs dressent un état des lieux des chantiers par projet en décrivant plus particulièrement les activités dans les domaines du traitement d’air et de refroidissement par eau.

76 FR 68101 - Safety Zone; Art Gallery Party St. Pete 2011 Fireworks Display, Tampa Bay, St. Petersburg, FL

Science.gov (United States)

2011-11-03

... questions on this temporary final rule, call or email Marine Science Technician First Class Nolan L. Ammons, Sector St. Petersburg Prevention Department, Coast Guard; telephone (813) 228-2191, email Nolan.L.Ammons...

Emergence in Taiwan of novel imipenem-resistant Acinetobacter baumannii ST455 causing bloodstream infection in critical patients.

Science.gov (United States)

Lee, Hao-Yuan; Huang, Chih-Wei; Chen, Chyi-Liang; Wang, Yi-Hsin; Chang, Chee-Jen; Chiu, Cheng-Hsun

2015-12-01

Acinetobacter baumannii is one of the most important nosocomial pathogens worldwide. This study aimed to use multilocus sequence typing (MLST) for the epidemiological surveillance of A. baumannii isolates in Taiwan and analyze the clinical presentations and patients' outcome. MLST according to both Bartual's PubMLST and Pasteur's MLST schemes was applied to characterize bloodstream imipenem-resistant A. baumannii (IRAB) infection in intensive care units in a medical center. A total of 39 clinical IRAB bloodstream isolates in 2010 were enrolled. We also collected 13 imipenem-susceptible A. baumannii (ISAB) bloodstream isolates and 30 clinical sputum isolates (24 IRAB and 6 ISAB) for comparison. Clinical presentations and outcome of the patients were analyzed. We found that infection by ST455(B)/ST2(P) and inappropriate initial therapy were statistically significant risk factors for mortality. More than one-third of the IRAB isolates belonged to ST455(B)/ST2(P). Most ST455(B)/ST2(P) (80%) carried ISAba1-blaOXA-23, including 10 (66.7%) with Tn2006 (ISAba1-blaOXA-23-ISAba1) in an AbaR4-type resistance island. ST455(B)/ST2(P) appears to evolve from ST208(B)/ST2(P) of clonal complex (CC) 92(B)/CC2(P). In this hospital-based study, A. baumannii ST455 accounted for 38.5% of IRAB bacteremia, with a high mortality of 86.7%. Approximately 85% of ST455(B)/ST2(P)bacteremia had a primary source of ventilation-associated pneumonia. We report the emergence in Taiwan of IRAB ST455(B)/ST2(P), which is the current predominant clone of IRAB in our hospital and has been causing bacteremia with high mortality in critical patients. Copyright © 2015. Published by Elsevier B.V.

ST6GalNAc-I controls expression of sialyl-Tn antigen in gastrointestinal tissues

DEFF Research Database (Denmark)

Marcos, Nuno T; Bennett, Eric P; Gomes, Joana

2011-01-01

Sialyl-Tn is a simple mucin-type carbohydrate antigen aberrantly expressed in gastrointestinal adenocarcinomas and in the precursor lesion intestinal metaplasia. Sialyl-Tn tumour expression is an independent indicator of poor prognosis. We have previously shown in vitro that ST6GalNAc-I and ST6GalNAc......-II sialyltransferases can synthesize sialyl-Tn. The aim of the present study was to establish whether ST6GalNAc-I is the major enzyme responsible for the expression of sialyl-Tn. We used a model of CHO-ldlD cells producing only MUC1-Tn glycoform and showed that ST6GalNAc-I is the key-enzyme leading to sialyl......-Tn biosynthesis. We developed novel monoclonal antibodies specific for ST6GalNAc-I and evaluated its expression in gastrointestinal tissues. ST6GalNAc-I was detected in normal colon mucosa co-localized with O-acetylated sialyl-Tn. Expression was largely unaltered in colorectal adenocarcinomas. In contrast, we...

Superconducting poloidal field magnet engineering for the ARIES-ST

International Nuclear Information System (INIS)

Bromberg, Leslie; Pourrahimi, S.; Schultz, J.H.; Titus, P.; Jardin, S.; Kessel, C.; Reiersen, W.

2003-01-01

The critical issues of the poloidal systems for the ARIES-ST design have been presented in this paper. Because of the large plasma current and the need of highly shaped plasmas, the poloidal field (PF) coils should be located inside the toroidal field in order to reduce their current. Even then, the divertor coils carry large currents. The ARIES-ST PF coils are superconducting using the internally cooled cable-in-conduit conductor. The peak self field in the divertor coils is about 15 T and the highest field in the non-divertor coils is about 6 T. The PF magnets have built-in margins that are sufficient to survive disruptions without quenching. The costing study indicates that the specific cost of the PF system is $80/kg. Detailed design and trade-off studies of ARIES-ST are presented and remaining R and D issues are identified

[Observation on therapeutic effect of electroacupuncture at Tianshu (ST 25) with deep needling technique on functional constipation].

Science.gov (United States)

Wang, Cheng-Wei; He, Hong-Bo; Li, Ning; Wen, Qian; Liu, Zhi-Shun

2010-09-01

To probe into a better therapeutic method for functional constipation. Ninety-five cases of functional constipation were randomly divided into deep puncture at ST 25 group (48 cases), shallow puncture at ST 25 group (24 cases) and medication group (23 cases). In deep puncture at ST 25 group, Tianshu (ST 25) was punctured deeply to the peritoneum, with electric stimulation. In shallow puncture at ST 25 group, Tianshu (ST 25) was punctured shallowly, 5 mm beneath the skin, with electric stimulation. In medication group, Duphalac was administered orally. These cases were treated continuously for 4 weeks in 3 groups and followed up for 6 months. It was to observe the numbers of person who had defecation 4 times a week, difference in weekly defecation frequency and the difference in the Cleveland Clinic Score (CCS). In deep puncture at ST 25 group, the frequency of weekly defecation and the numbers of person who had defecation 4 times a week increased and CCS decreased, which were similar to the efficacy in shallow puncture at ST 25 group (all P > 0.05). But the efficacy of both ST 25 groups was superior to that in medication group (both P deep puncture at ST 25 group acted more quickly than either shallow puncture at ST 25 group or medication group and its efficacy remained much longer. The deep puncture at ST 25 with electric stimulation presents similar efficacy on functional constipation as shallow puncture at ST 25, but it acts more quickly than shallow puncture at ST 25, both of them are more advantageous than medication and the long-term efficacy is better.

77 FR 42642 - Safety Zone; City of Ogdensburg Fireworks, St. Lawrence River, Ogdensburg, NY

Science.gov (United States)

2012-07-20

...-AA00 Safety Zone; City of Ogdensburg Fireworks, St. Lawrence River, Ogdensburg, NY AGENCY: Coast Guard... portion of the St. Lawrence River during the City of Ogdensburg Fireworks display. This temporary safety... as follows: Sec. 165.T09-0608 Safety Zone; City of Ogdensburg Fireworks, St. Lawrence River...

Light spectrum on the quality of fruits of physalis species in subtropical area

Directory of Open Access Journals (Sweden)

Daniel Fernandes da Silva

2016-01-01

Full Text Available ABSTRACT The aim of this study was to analyze the effect of colored-shade nets on the physicochemical characteristics of physalis in subtropical area. The experimental design was the randomized blocks with a 4 × 5 factorial, being four species of physalis (Physalis peruviana, P. pubescens, P. minima and P. ixocarpa and four net colors (white, blue, red and black, besides the control under full sun. Titratable acidity (TA, pH, vitamin C, soluble solids (SS, SS/TA relation, total phenolics, anthocyanins and antioxidant capacity were evaluated. It was observed that P. peruviana and P. pubescens have more acid fruits, and P. minima shows vitamin C content higher than the other species. In general, fruits of P. peruviana and P. pubescens have better quality when grown in white, blue or black shade net; fruits of P. minima are physicochemically superior when produced under full sun or under white or blue shade net; finally, fruits of P. ixocarpa have low quality when produced under black net.

Moscow and St. Petersburgpsychological schools: from opposition to friendship

Directory of Open Access Journals (Sweden)

Victor M. Allakhverdov

2016-09-01

Full Text Available The paper is an attempt to summarize the interaction of the two largest schools of psychology in Russia: the psychological schools of Moscow and St. Petersburg. The paper is a sketch dedicated to the 50th anniversary of the psychological faculties of Moscow and St. Petersburg, and should not be appreciated as a historical treatise. Tense ties between the psychological schools, that originate in the distant past, have gone through different historical stages. Slavophilevs Westernizer traditions affected the initial difference in these schoolsemerging into the opposition: either the human being is studied entirety with his/her vast subjective experience, but losing the reliability of our statements (peculiarity of Moscow school, or we study the human being accurately using objective methods, but losing the integrity of our ideas (peculiarity of St.-Petersburg school. Both psychological schools, having gone through the ups and downs, have retained their identity and their emphasis on research. Moscow scholars in their studies are aimed to larger issues and still rely on large-scale Vygotsky-Leontiev approach. Scholars of St.-Petersburgtouch upon more specific issues using empirical methods, but still continue with nostalgia and hope making plans about creating a common concept of human individual according to Ananiev. Nowadays between the two schools there is no opposition, but only one mutual love.

33 CFR 110.250 - St. Thomas Harbor, Charlotte Amalie, V.I.

Science.gov (United States)

2010-07-01

... 33 Navigation and Navigable Waters 1 2010-07-01 2010-07-01 false St. Thomas Harbor, Charlotte... SECURITY ANCHORAGES ANCHORAGE REGULATIONS Anchorage Grounds § 110.250 St. Thomas Harbor, Charlotte Amalie.... Thomas, V.I. of the United States and approaches thereto, including all waters under its jurisdiction, as...

New FIGO and Swedish intrapartum cardiotocography classification systems incorporated in the fetal ECG ST analysis (STAN) interpretation algorithm: agreements and discrepancies in cardiotocography classification and evaluation of significant ST events.

Science.gov (United States)

Olofsson, Per; Norén, Håkan; Carlsson, Ann

2018-02-01

The updated intrapartum cardiotocography (CTG) classification system by FIGO in 2015 (FIGO2015) and the FIGO2015-approached classification by the Swedish Society of Obstetricians and Gynecologist in 2017 (SSOG2017) are not harmonized with the fetal ECG ST analysis (STAN) algorithm from 2007 (STAN2007). The study aimed to reveal homogeneity and agreement between the systems in classifying CTG and ST events, and relate them to maternal and perinatal outcomes. Among CTG traces with ST events, 100 traces originally classified as normal, 100 as suspicious and 100 as pathological were randomly selected from a STAN database and classified by two experts in consensus. Homogeneity and agreement statistics between the CTG classifications were performed. Maternal and perinatal outcomes were evaluated in cases with clinically hidden ST data (n = 151). A two-tailed p ST events, heterogeneities were significant and agreements moderate to almost perfect (STAN2007 vs. FIGO2015 0.86, 0.72; STAN2007 vs. SSOG2017 0.92, 0.84; FIGO2015 vs. SSOG2017 0.94, 0.87). Significant ST events occurred more often combined with STAN2007 than with FIGO2015 classification, but not with SSOG2017; correct identification of adverse outcomes was not significantly different between the systems. There are discrepancies in the classification of CTG patterns and significant ST events between the old and new systems. The clinical relevance of the findings remains to be shown. © 2017 The Authors. Acta Obstetricia et Gynecologica Scandinavica published by John Wiley & Sons Ltd on behalf of Nordic Federation of Societies of Obstetrics and Gynecology (NFOG).

Diagnostic value for coronary artery disease of ST depression and chest pain during dipyridamole loading

International Nuclear Information System (INIS)

Yonezawa, Yoshihiro; Doi, Yoshinori; Aono, Tadashi; Odawara, Hiroaki; Chikamori, Taishiro; Yamada, Mitsutoshi; Takata, Jun; Ozawa, Toshio; Hamashige, Naohisa.

1991-01-01

The diagnostic significance of both ST depression and chest pain during dipyridamole loading was assessed in 437 patients with coronary artery disease (CRD) who have received dipyridamole-loading thallium-201 myocardial scintigraphy and coronary arteriography. ST depression and chest pain were induced in 35% and 42%, respectively. ST depression occurred in 23% for one vessel disease, 55% for two-vessel disease, 67% for three-vessel disease, and 11% for non-significant disease. In the absence of myocardial infarction, it occurred in as many as 78% for two-vessel disease and 94% for three-vessel disease. ST depression had a sensitivity of 51% and a specificity of 89%. Chest pain had a lower specificity (77%), whereas the sensitivity remained the same (51%). In 42 (31%) of 134 patients with ST depression, coronary revascularization was necessary in the early stage. With a median follow up of 29 months, 3 patients (2%) died of cardiac events, and 12 (9%) had nonfatal cardiac complications. There was a significant correlation between reversible defects (RD) on myocardial scintigrams and ST depression; RD were seen in 81% of ST depression cases, and ST depression occurred in 51% of 210 RD cases. The more diseased vessels, the more frequently ST depression occurred in accordance with RD on myocardial scintigrams. Both ST depression and chest pain during dipyridamole loading tended to be associated with myocardial ischemia, suggesting the diagnostic value in CRD patients with limited exercise loading. RD on myocardial scintigrams was considered attributable to coronary steal phenomenon for multi-vessel disease and to the difference in the relative increase of the coronary flow for single vessel disease. (N.K.)

21st Century Power Partnership: September 2016 Fellowship Report

Energy Technology Data Exchange (ETDEWEB)

Reber, Timothy J. [National Renewable Energy Lab. (NREL), Golden, CO (United States); Rambau, Prudence [Eskom, Pretoria (South Africa); Mdhluli, Sipho [Eskom, Pretoria (South Africa)

2017-09-29

This report details the 21st Century Power Partnership fellowship from September 2016. This Fellowship is a follow-up to the Technical Audit of Eskom's Medium- and Long-term Modelling Capabilities, conducted by U.S. National Renewable Energy Laboratory (NREL) in April 2016. The prospect and role of variable renewable energy (vRE) in South Africa poses new modelling-related challenges that Eskom is actively working to address by improving the fidelity of PLEXOS LT and ST models.

In Vitro Evaluation of Beneficial Properties of Bacteriocinogenic Lactobacillus plantarum ST8Sh.

Science.gov (United States)

Todorov, Svetoslav Dimitrov; Holzapfel, Wilhelm; Nero, Luis Augusto

2017-06-01

Lactobacillus plantarum ST8Sh, isolated from Bulgarian salami "shpek" and previously characterized as bacteriocin producer, was evaluated for its beneficial properties. Based on the PCR analysis, Lb. plantarum ST8Sh was shown to host a gene related to the production of adhesion proteins such as Mab, Mub, EF, and PrgB. Genetic and physiological tests suggest Lb. plantarum ST8Sh to represent a potential probiotic candidate, including survival in the presence of low levels of pH and high levels of ox bile, production of β-galactosidase, bile salt deconjugation, high level of hydrophobicity, functional auto- and co-aggregation properties, and adhesion to cell lines. Application of semi-purified bacteriocin produced by Lb. plantarum ST8Sh in combination with ciprofloxacin presented synergistic effect on inhibition of Listeria monocytogenes Scott A. Based on observed properties, Lb. plantarum ST8Sh can be considered as a potential probiotic candidate with additional bacteriocinogenic properties.

Níveis de PCR são maiores em pacientes com síndrome coronariana aguda e supradesnivelamento do segmento ST do que em pacientes sem supradesnivelamento do segmento ST Niveles de PCR son mayores en pacientes con síndrome coronario agudo y supradesnivel del segmento ST que en pacientes sin supradesnivel del segmento ST CRP levels are higher in patients with ST elevation than non-ST elevation acute coronary syndrome

Directory of Open Access Journals (Sweden)

Syed Shahid Habib

2011-01-01

Full Text Available FUNDAMENTO: Há grande interesse no uso de proteína C-reativa de alta sensibilidade (PCR-as para avaliação de risco. Altos níveis de PCR-as no início da síndrome coronária aguda (SCA, antes da necrose tecidual, pode ser um marcador substituto para comorbidades cardiovasculares. OBJETIVO: Dessa forma, nosso objetivo foi estudar diferentes medidas de seguimento de níveis de PCR-as em pacientes com SCA e comparar as diferenças entre infarto do miocárdio sem elevação do segmento ST (NSTEMI com pacientes apresentando elevação do segmento ST (STEMI. MÉTODOS: Este é um estudo observacional. Dos 89 pacientes recrutados, 60 apresentavam infarto agudo do miocárdio (IAM. Três níveis seriados de PCR-us, a nível basal na hospitalização antes de 12 horas após inicio dos sintomas, níveis de pico 36-48 horas após hospitalização e níveis de acompanhamento após 4 a 6 semanas foram analisados e comparados entre pacientes com (IAMCSST e sem supradesnivelamento do segmento ST (IAMSSST. RESULTADOS: Pacientes com IAMCSST tinham IMC significantemente mais alta quando comparados com pacientes IAMSSST. Os níveis de creatino quinase fração MB (CK-MB e aspartato aminotransferase (AST eram significantemente mais altos em pacientes com IAMCSST quando comparados com pacientes com IAMSSST (pFUNDAMENTO: Hay gran interés en el uso de proteína C-reactiva de alta sensibilidad (PCR-as para evaluación de riesgo. Altos niveles de PCR-as en el comienzo del síndrome coronario agudo (SCA, antes de la necrosis tisular, puede ser un marcador sustituto para comorbilidades cardiovasculares. OBJETIVO: De esa forma, nuestro objetivo fue estudiar diferentes medidas de seguimiento de niveles de PCR-as en pacientes con SCA y comparar las diferencias entre infarto de miocardio sin elevación del segmento ST (NSTEMI con pacientes presentando elevación del segmento ST (STEMI. MÉTODOS: Este es un estudio observacional. De los 89 pacientes reclutados, 60

Education for Employment in Nigeria in the 21st Century: Some ...

African Journals Online (AJOL)

This paper examined education for employment in Nigeria in the 21st Century. This paper therefore looked at the demand of workplace employment skills, learning skills, literacy skills and life skills. This paper concludes by advocating how to teach 21st Century employment skills, how to guarantee gainful employment, and ...

Design assumptions and bases for small D-T-fueled Sperical Tokamak (ST) fusion core

International Nuclear Information System (INIS)

Peng, Y.K.M.; Galambos, J.D.; Fogarty, P.J.

1996-01-01

Recent progress in defining the assumptions and clarifying the bases for a small D-T-fueled ST fusion core are presented. The paper covers several issues in the physics of ST plasmas, the technology of neutral beam injection, the engineering design configuration, and the center leg material under intense neutron irradiation. This progress was driven by the exciting data from pioneering ST experiments, a heightened interest in proof-of-principle experiments at the MA level in plasma current, and the initiation of the first conceptual design study of the small ST fusion core. The needs recently identified for a restructured fusion energy sciences program have provided a timely impetus for examining the subject of this paper. Our results, though preliminary in nature, strengthen the case for the potential realism and attractiveness of the ST approach

The GEOSS Science and Technology Stakeholder Network and Service Suite: Linking S&T Communities and GEOSS

Science.gov (United States)

Plag, Hans-Peter; Jules-Plag, Shelley

2015-04-01

The Global Earth Observation System of Systems (GEOSS) developed by the Group on Earth Observations (GEO) aims to provide practice-relevant knowledge in support of decision making in a wide range of societal benefit areas. Generating this practice-relevant knowledge based on Earth observations, socio-economic data and models often depends on research, and utilization of the societal benefits of EOs requires the involvement of science and research communities. Building a GEOSS responding to the needs of a wide range of users necessitates contributions from many science and technology (S&T) communities. In particular, a strong engagement of science and technology (S&T) communities in both the development and use of GEOSS is necessary to address the complex issues associated with the on-going transition out of the Holocene. S&T support is needed to improve interoperability between global observing, modeling, and information systems; to enable data integration across disciplinary boundaries; to facilitate data sharing, archiving, dissemination, and reanalysis; to optimize the recording of observations, assimilation of data into models, and generation of data products; to enhance the value of observations from individual observing systems through their integration in the SBAs; and to harmonize well-calibrated, highly accurate, stable, sustained in-situ and satellite observations of the same variable recorded by different sensors and different agencies. Consequently, the GEO Work Plan includes several Tasks focusing on outreach to S&T communities, and most of the GEO Community of Practice have a strong S&T component. The GEOSS S&T Stakeholder Network facilitates input from S&T communities to GEO. Infrastructure serving and linking S&T users communities and GEOSS has been developed and is integrated into a GEOSS S&T Service Suite (GSTSS). The GSTSS has several outreach components for the demonstration of GEOSS and its value for S&T communities, and for services supporting

Středisko volného času Kostka

OpenAIRE

Křenková, Romana

2017-01-01

Tématem diplomové práce je novostavba školního zařízení Střediska volného času Kostka. SVČ je samostatně stojící objekt na mírně svažitém pozemku, se dvěma nadzemními podlažími. Objekt není podsklepen. SVČ se nachází vedle mateřské školy a základní školy. Dispozičně zahrnuje objekt 11 učeben a je navržen pro 163 dětí. Obvodové, vnitřní nosné i nenosné stěny jsou navrženy z cihelných bloků. Stropy jsou tvořeny pomocí předpjatých stropních panelů. Objekt je zastřešen jednoplášťovou plochou stře...

A look at S&T Awareness - Enhancements in India

Directory of Open Access Journals (Sweden)

Chandra Mohan Nautiyal

2008-06-01

Full Text Available Basing mainly on author's direct involvement in some science communication efforts in India, and other reports, this contribution depicts and analyses the present science communication/ popularization scenario in India. It tries to dispel a myth that rural people don't require or don’t crave for S&T information. It discusses need for science and technology communication, sustaining curiosity and creating role models. Citing cases of some natural, 'unnatural' and organized events, it recounts how S&T popularization efforts have fared during the past decade and a half. It's made possible using print, AV and interactive media which, at times, require lot of financial inputs. However, this contribution shows that a number of natural and other phenomena can be used to convince people about power of S&T and in molding their attitude. The cases cited may be from India, but, with a little variation, are true for most of the developing and under- developed societies.

Bimetal cup hydroforming of Al/St and Cu/St composites: Adaptive finite element analysis and experimental study

Energy Technology Data Exchange (ETDEWEB)

Hashemi, Abbas; Gollo, Mohammad Hoseinpour [Shahid Rajaee Teacher Training University, Tehran (Iran, Islamic Republic of); Seyedkashi, S. M. [University of Birjand, Birjand (Iran, Islamic Republic of)

2016-05-15

An adaptive Finite element analysis (FEA) was proposed in this paper for the industrial design of bimetal conical-cylindrical cup hydroforming. Forming circumstances for the perfect and imperfect parts were concluded through adaptive FEA using the ANSYS parametric design language. Effective parameters, including pressure loading path, layer placement order, and thickness ratio, were investigated for hydroforming of Al/St and Cu/St composite sheets. Experimental tests were implemented to validate adaptive finite element results. Rupture failure upon the pressure path occurred on the contact area between the blank and punch tip radius at low pressures and on the transition area of the conical-cylindrical portion at high pressures. The proposed method is applicable for any cylindrical, conical, or cylindrical/conical shapes with different materials and dimensions. Therefore, this method is beneficial as a practical design tool for engineers and researchers working in the process design of hydroformed shell products.

Severe Hyperthyroidism Presenting with Acute ST Segment Elevation Myocardial Infarction

Directory of Open Access Journals (Sweden)

Dayan Zhou

2015-01-01

Full Text Available Introduction. Acute myocardial infarction is life-threatening. A cardiac troponin rise accompanied by typical symptoms, ST elevation or depression is diagnostic of acute myocardial infarction. Here, we report an unusual case of a female who was admitted with chest pain. However, she did not present with a typical profile of an acute myocardial infarction patient. Case Presentation. A 66-year-old Han nationality female presented with chest pain. The electrocardiogram (ECG revealed arched ST segment elevations and troponin was elevated. However, the coronary angiography showed a normal coronary arterial system. Thyroid function tests showed that this patient had severe hyperthyroidism. Conclusion. Our case highlights the possibility that hyperthyroidism may cause a large area of myocardium injury and ECG ST segment elevation. We suggest routine thyroid function testing in patients with chest pain.

St. Laurent Construction Co., Inc. Information Sheet

Science.gov (United States)

St. Laurent Construction Co., Inc. (the Company) is located in Nashua, New Hampshire. The settlement involves renovation activities conducted at properties constructed prior to 1978, located in Merrimack and Nashua, New Hampshire.

Minimal pneumothorax with dynamic changes in ST segment similar to myocardial infarction.

Science.gov (United States)

Yeom, Seok-Ran; Park, Sung-Wook; Kim, Young-Dae; Ahn, Byung-Jae; Ahn, Jin-Hee; Wang, Il-Jae

2017-08-01

Pneumothorax can cause a variety of electrocardiographic changes. ST segment elevation, which is mainly observed in myocardial infarction, can also be induced by pneumothorax. The mechanism is presumed to be a decrease in cardiac output, due to increased intra-thoracic pressure. We encountered a patient with ST segment elevation with minimal pneumothorax. Coronary angiography with ergonovine provocation test and echocardiogram had normal findings. The ST segment elevation was normalized by decreasing the amount of pneumothorax. We reviewed the literature and present possible mechanisms for this condition. Copyright © 2017 Elsevier Inc. All rights reserved.

Adult Enrichment Learners in St. Cloud, Minnesota: Motivational Reasons for Participation

Science.gov (United States)

Wallner, Scott David

2012-01-01

The purpose of the study was to identify reasons and motivation of adult stakeholders that influence participation in adult community education enrichment classes in the St. Cloud Public School District, St. Cloud, Minnesota. The study also examined the perceptions about adult learners held by leaders, planners, and facilitators of these programs,…

The effect of porcine somatotropin (pST) and gender on production ...

African Journals Online (AJOL)

The effect of porcine somatotropin (pST) and gender on production parameters and tissue yield of pigs slaughtered at 135 kg live weight. ... No significant pST effects were found for live weight, carcass weight, % bone, % fat or % lean meat, but a significant increase in percentage skin was found. Keywords: triterpenoid, stem ...

ST peak during primary percutaneous coronary intervention predicts final infarct size, left ventricular function, and clinical outcome

DEFF Research Database (Denmark)

Lønborg, Jacob Thomsen; Kelbæk, Henning Skov; Holmvang, Lene

2012-01-01

One third of patients treated with primary percutaneous coronary intervention (PCI) for ST-elevation myocardial infarction develop a secondary increase in electrocardiographic ST segment (ST peak) during reperfusion. The purpose was to determine the clinical importance of ST peak during primary PCI....

Improved early risk stratification of patients with ST-segment elevation myocardial infarction undergoing primary percutaneous coronary intervention using a combination of serum soluble ST2 and NT-proBNP.

Directory of Open Access Journals (Sweden)

Jongwook Yu

Full Text Available Although soluble suppression of tumorigenicity 2 (sST2 in serum is known to be associated with ischemic heart disease and heart failure, data regarding its prognostic impact in ST-segment elevation myocardial infarction (STEMI is limited. We evaluated the prognostic impacts of serum sST2 and other serum biomarkers in STEMI patients undergoing primary percutaneous coronary intervention (PCI.Consecutive all 323 patients with STEMI that underwent primary PCI were enrolled. Blood tests and samples were obtained in an emergency room. The primary endpoint was 1-year major adverse cardiovascular and cerebrovascular events (MACCEs, defined as a composite of cardiovascular death, non-fatal MI, non-fatal stroke, and ischemia-driven revascularization.Mean age was 59.1±13.1 years (men 84%. MACCE (20 cardiovascular deaths, 7 non-fatal MI, 4 non-fatal stroke, 7 ischemia-driven revascularizations occurred in 38 patients (12%. After adjusting for confounding factors, Cox regression analysis revealed that high serum sST2 (>75.8 ng/mL mean value, adjusted hazard ratio 2.098, 95% CI 1.008-4.367, p = 0.048 and high serum NT-proBNP level (>400 pg/mL, adjusted hazard ratio 2.606, 95% CI 1.086-6.257, p = 0.032 at the time of presentation independently predicted MACCE within a year of primary PCI. Furthermore, when high serum sST2 level was combined with high serum NT-proBNP level, the hazard ratio of MACCE was highest (adjusted hazard ratio 7.93, 95% CI 2.97-20.38, p<0.001.Elevated serum levels of sST2 or NT-proBNP at the time of presentation were found to predict 1-year MACCE independently and elevated serum levels of sST2 plus NT-proBNP were associated with even poorer prognosis in patients with STEMI undergoing primary PCI.

1st quarterly report 1977

International Nuclear Information System (INIS)

1977-06-01

The present report describes the activities carried out in the 1st quarter of 1977 at the Gesellschaft fuer Kernforschung in Karlsruhe or on its behalf in the framework of the fast breeder project (PSB). The problems and main results of the partial projects fuel rod development, materials testing, reactor physics, reactor safety and reactor technology are presented. (RW) [de

78 FR 71037 - St. Lawrence & Atlantic Railroad Company-Discontinuance of Service Exemption-in Cumberland County...

Science.gov (United States)

2013-11-27

... DEPARTMENT OF TRANSPORTATION Surface Transportation Board [Docket No. AB 1117X] St. Lawrence..., 2013, St. Lawrence & Atlantic Railroad Company (SLR) filed with the Surface Transportation Board (Board..., FD 35440 (STB served Dec. 29, 2010); Maine--Acquisition Exemption--Certain Assets of St. Lawrence...

Interobserver reliability of the Amsterdam Severity Scale in Stenosing Tenosynovitis (ASSiST)

NARCIS (Netherlands)

Peter, W.F.; Steultjens, M.P.M.; Mesman, T.; Dekker, J.; Hoeksma, A.F.

2009-01-01

STUDY DESIGN: Interobserver reliability study. INTRODUCTION: A scale was developed to measure the severity of stenosing tenosynovitis: the Amsterdam Severity Scale in Stenosing Tenosynovitis (ASSiST). PURPOSE OF THE STUDY: To study the interobserver reliability of the ASSiST. METHODS: Patients

Association of HS6ST3 gene polymorphisms with obesity and ...

Indian Academy of Sciences (India)

The heparan sulfate 6-O-sulfotransferase 3 (HS6ST3) gene is involved in heparan sulphate and heparin metabolism, and has been reported to be associated with diabetic retinopathy in type 2 diabetes. We hypothesized that HS6ST3 gene polymorphisms might play an important role in obesity and related phenotypes (such ...

The Effect of Artificial Aging on the Tensile Properties of Alclad 24S-T and 24S-T Aluminum Alloy

Science.gov (United States)

Kotanchik, Joseph N.; Woods, Walter; Zender, George W.

1943-01-01

An experimental study was made to determine the effect of artificial aging on the tensile properties of alclad 24S-T and 24S-T aluminum-alloy sheet material. The results of the tests show that certain combinations of aging time and temperature cause a marked increase in the yield strength and a small increase in the ultimate strength; these increases are accompanied by a very large decrease in elongation. A curve is presented that shows the maximum yield strengths that can be obtained by aging this material at various combinations of time and temperature. The higher values of yield stress are obtained in material aged at relatively longer times and lower temperatures.

Detergents of the 21st century

Directory of Open Access Journals (Sweden)

Ho Tan Tai Louis

2001-03-01

Full Text Available Detergents of the 21st century will depend on evolutions in household appliances, in substrates and in consumer needs. In addition, the environmental constraints, which become more and more stringent, will also play an important role, particularly in the formulations. Surfactants, which constitute one of the main raw materials in detergents, will have to be more environmentally friendly with increasing criteria of biodegradability and renewable materials. Builders (phosphates or zeolithes, heavy metal complexants (EDTA and bleaching agents (combination perborate/TAED are also expected to be replaced by biodegradable compounds, with better performances and lower costs. The real raw materials of the detergents of the 21st century will probably be enzymes (oxidase, hydrolase, peroxidase which present several advantages. At the same time, efforts will be made on biodegradable packaging through the use of micro-organisms able to degrade polymers. Finally, in terms of product forms, the concept of concentration might come back through the use of tablets.

Dream of petroleum and petrochemical industries in the 21st century

Energy Technology Data Exchange (ETDEWEB)

Fujimoto, Kaoru; Sugioka, Masatoshi; Yoshizumi, Satoshi; Ishida, Kazufumi; Nakagawa, Takashi; Kamiyama, Hiroteru; Nagaoka, Takenori

1988-10-01

This paper summarizes the symposium held on June 6, 1988 to celebrate the 30th anniversary of the Petroleum Society. The themes discussed are as follows: (1) The oil crisis was a common experience. (2) Petroleum resources will be available by the middle 21st century. (3) The crude oil market will be led by OPEC again. (4) The petroleum demand will remain unchanged because of increase in developing countries and reduction in developed countries. (5) The development of alternative energy will be the key to the third oil crisis. (6) The combination of batch and flow processes is a key to refinery technology. (7) Low-cost refinery technology should be used in response to product import. (8) The main products will still be gasoline and kerosene also in the 21st century. (9) New petroleum refinery technology will focus on separation and reaction under low-temperature and low-pressure conditions. (10) Diversification in material will change petrochemistry. (11) Polymers in the 21st century will be multi-functional. (12) Outlook and dream for the 21st century.

St. John Shallow-water Ground Validation Sites

Data.gov (United States)

National Oceanic and Atmospheric Administration, Department of Commerce — Benthic habitat maps of the nearshore marine environment of St. John, U.S. Virgin Islands were created by visual interpretation of remotely sensed imagery. The...

Location - Managed Facility - St. Paul District (MVP)

Data.gov (United States)

Army Corps of Engineers, Department of the Army, Department of Defense — St. Paul District - US Army Corps of Engineers Managed Facility locations. District headquarters, Natural Resource, Recreation, Lock and Dam, and Regulatory offices...

Microalbuminuria modifies the mortality risk associated with electrocardiographic ST-T segment changes

NARCIS (Netherlands)

Diercks, GFH; Hillege, HL; van Boven, AJ; Kors, JA; Crijns, HJGM; Grobbee, DE; de Jong, PE; van Gilst, WH

2002-01-01

OBJECTIVES We sought to investigate whether microalbuminuria, a proposed marker of generalized vascular damage, enhances the prognostic value of ST-T segment changes for all-cause and cardiovascular mortality in the general population. BACKGROUND ST-T segment changes on the rest electrocardiogram

Marine geology of the St. Lawrence Estuary

Energy Technology Data Exchange (ETDEWEB)

St-Onge, Guillaume [Canada Research Chair in Marine Geology, Institut des sciences de la mer de Rimouski (ISMER) and GEOTOP Research Center, 310 allee des Ursulines, Rimouski, Quebec, G5L 3A1 (Canada); Duchesne, Mathieu J [Geological Survey of Canada, Quebec Division, 490 de la Couronne, Quebec City, Quebec, G1K 9A9 (Canada); Lajeunesse, Patrick, E-mail: guillaume_st-onge@uqar.qc.ca [Departement de geographie and Centre d' etudes nordiques, Universite Laval, Quebec City, Quebec, G1V 0A6 (Canada)

2011-05-15

The St. Lawrence Estuary, Eastern Canada, contains a very thick (>450 m) Quaternary sedimentary sequence. The results from recently conducted geophysical surveys in conjunction with piston coring indicate that these sediments were deposited under very high sedimentation rates, sometimes as high as {approx}30 m/ka during the last deglaciation. Results also reveal evidence of large submarine landslides during the Holocene, changes in sedimentation rates and the significant role of submarine canyons and channels to transfer sediments from the coast to the deeper marine environment. Finally, this paper highlights the presence of more than 1900 pockmarks on the seafloor of the St. Lawrence Estuary and discusses their possible origins: active hydrocarbon seeps in the Laurentian Channel and biogenic gas seepage on the northwestern shoulder of the Laurentian Channel.

Marine geology of the St. Lawrence Estuary

International Nuclear Information System (INIS)

St-Onge, Guillaume; Duchesne, Mathieu J; Lajeunesse, Patrick

2011-01-01

The St. Lawrence Estuary, Eastern Canada, contains a very thick (>450 m) Quaternary sedimentary sequence. The results from recently conducted geophysical surveys in conjunction with piston coring indicate that these sediments were deposited under very high sedimentation rates, sometimes as high as ∼30 m/ka during the last deglaciation. Results also reveal evidence of large submarine landslides during the Holocene, changes in sedimentation rates and the significant role of submarine canyons and channels to transfer sediments from the coast to the deeper marine environment. Finally, this paper highlights the presence of more than 1900 pockmarks on the seafloor of the St. Lawrence Estuary and discusses their possible origins: active hydrocarbon seeps in the Laurentian Channel and biogenic gas seepage on the northwestern shoulder of the Laurentian Channel.

Evaluation of the yield, molar mass of exopolysaccharides, and rheological properties of gels formed during fermentation of milk by Streptococcus thermophilus strains St-143 and ST-10255y.

Science.gov (United States)

Khanal, Som N; Lucey, John A

2017-09-01

The yield and chemical structures of exopolysaccharides (EPS) produced by many strains of Streptococcus thermophilus have been characterized. However, the kinetics (or production profile) for EPS during milk fermentation is not clear. In this study, we investigated whether any differences existed in the yield and molar mass of EPS when milk was fermented at the same acidification rate by 2 strains of S. thermophilus (St-143 and ST-10255y). The type of EPS produced by these 2 strains is different. Milk samples were analyzed for EPS concentration every 30 min during a fermentation period of 270 min (final pH 4.5) by using a modified quantification method, which was faster and validated for its recovery of added EPS. Rheological properties of milks during fermentation were also analyzed using small-strain dynamic oscillatory rheology. For the determination of molar mass, EPS extracts were isolated by ultrafiltration of whey obtained during fermentation of milk to pH values 5.2, 4.9, 4.7, and 4.5, and molar mass was analyzed using size-exclusion chromatography-multi-angle laser light scattering. During fermentation, both strains appeared to start producing significant amounts of EPS after about ∼150 min, which corresponded to pH ∼5.3, which was close to the point of gelation. During the remainder of the fermentation process (150-270 min), the EPS concentration from strains St-143 and ST-10255y significantly increased from 30 to 72 mg/L and from 26 to 56 mg/L, respectively. The quantity of EPS recovered by our modified method was estimated to represent ∼60% of the total EPS added to milk. The molar mass of EPS produced by both strains appeared to slightly decrease during fermentation. At pH 5.2, EPS from St-143 and ST-10255y had molar masses of 2.9 × 10 6 and 1.4 × 10 6 g/mol, respectively, which decreased to 1.6 × 10 6 and 0.8 × 10 6 g/mol, respectively, when the pH of milk was 4.5. Distinct differences were apparent in the rheological properties of gels

The new Facilities Management contract at CERN from 1st July 2002

CERN Document Server

Mauro Nonis

2002-01-01

Within the ST Division, all the Facilities Management activities have been under the ST/TFM group responsibility until the 30th June 2002, who has performed them using around 20 industrial support contracts. Starting from the 1st July 2002 a new unit, ST/FM, will take over these activities that will be unified into one single contract that has been adjudicated to the company Facilities Management Network SA. This contract will be in charge of the maintenance and minor works on tertiary installations (i.e. all structures and installations that have no direct relation to the running of the accelerators) for the following trades: - Technical: heating, ventilation, air conditioning, plumbing, electricity, civil engineering (painting, roofing, glazing, blinds, fencing, masonry etc.), passenger and goods lifts, automatic and powered doors, kitchen equipment, roads, signs, keys and locks, office furniture, - Services: waste collection, security, green areas, cleaning and sanitary supplies, disinfection, rodent cont...

THE NEW FACILITIES MANAGEMENT CONTRACT AT CERN FROM 1st JULY 2002

CERN Multimedia

Mauro Nonis

2002-01-01

Within the ST Division, all the Facilities Management activities have been under the ST/TFM group responsibility until the 30th June 2002, who has performed them using around 20 industrial support contracts. Starting from the 1st July 2002 a new unit, ST/FM, will take over these activities that will be unified into one single contract that has been adjudicated to the company Facilities Management Network SA. This contract will be in charge of the maintenance and minor works on tertiary installations (i.e. all structures and installations that have no direct relation to the running of the accelerators) for the following trades: Technical: heating, ventilation, air conditioning, plumbing, electricity, civil engineering (painting, roofing, glazing, blinds, fencing, masonry etc.), passenger and goods lifts, automatic and powered doors, kitchen equipment, roads, signs, keys and locks, office furniture, Services: waste collection, security, green areas, cleaning and sanitary supplies, disinfection, rodent contro...

Bakteriochlorophyllvorstufen und Pigment-Protein-Komplexe in Rhodospirillum rubrum ST3 und GN11

OpenAIRE

Hammel, Jörg U.

2006-01-01

In der vorliegenden Arbeit wurden zwei Mutanten des Alpha-Proteobakteriums Rhodospirillum rubrum untersucht, die im Bakteriochlorophyll-Biosyntheseweg unterbrochen sind, um einen Beitrag zum genaueren Verständnis der Biosynthese dieser Moleküle und der einzelnen daran beteiligten Schritte zu liefern. Von den beiden Stämmen ST3 und GN11 wurden die ins Kulturmedium ausgeschiedenen Pigmente aufgereinigt und spektroskopisch analysiert. Ebenfalls wurden sowohl von ST3, als auch von GN11 die in int...

ST2 negatively regulates TLR2 signaling, but is not required for bacterial lipoprotein-induced tolerance.

LENUS (Irish Health Repository)

Liu, Jinghua

2010-05-15

Activation of TLR signaling is critical for host innate immunity against bacterial infection. Previous studies reported that the ST2 receptor, a member of the Toll\\/IL-1 receptor superfamily, functions as a negative regulator of TLR4 signaling and maintains LPS tolerance. However, it is undetermined whether ST2 negatively regulates TLR2 signaling and furthermore, whether a TLR2 agonist, bacterial lipoprotein (BLP)-induced tolerance is dependent on ST2. In this study, we show that BLP stimulation-induced production of proinflammatory cytokines and immunocomplex formation of TLR2-MyD88 and MyD88-IL-1R-associated kinase (IRAK) were significantly enhanced in ST2-deficient macrophages compared with those in wild-type controls. Furthermore, overexpression of ST2 dose-dependently attenuated BLP-induced NF-kappaB activation, suggesting a negative regulatory role of ST2 in TLR2 signaling. A moderate but significantly attenuated production of TNF-alpha and IL-6 on a second BLP stimulation was observed in BLP-pretreated, ST2-deficient macrophages, which is associated with substantially reduced IRAK-1 protein expression and downregulated TLR2-MyD88 and MyD88-IRAK immunocomplex formation. ST2-deficient mice, when pretreated with a nonlethal dose of BLP, benefitted from an improved survival against a subsequent lethal BLP challenge, indicating BLP tolerance develops in the absence of the ST2 receptor. Taken together, our results demonstrate that ST2 acts as a negative regulator of TLR2 signaling, but is not required for BLP-induced tolerance.

76 FR 21939 - Noise Exposure Map; Receipt of Noise Compatibility Program and Request for Review; Lambert-St...

Science.gov (United States)

2011-04-19

... Compatibility Program and Request for Review; Lambert-St. Louis International Airport, St. Louis, MO AGENCY...) announces its determination that the noise exposure maps submitted by the St. Louis Airport Authority for the Lambert-St. Louis International Airport under the provisions of 49 U.S.C. 47501 et seq. (Aviation...

Aiming Talent Development toward Creative Eminence in the 21st Century

Science.gov (United States)

Olszewski-Kubilius, Paula; Subotnik, Rena F.; Worrell, Frank C.

2016-01-01

Much has been written about the social and scientific problems that face the world in the 21st century, including climate change and economic inequality. In this context, the development of talented individuals who can tackle these problems is most important. In this article, the authors discuss the implications of 21st-century challenges for the…

2008 St. Johns County, FL Countywide Lidar

Data.gov (United States)

National Oceanic and Atmospheric Administration, Department of Commerce — Airborne terrestrial LiDAR was collected for St. Johns County, FL. System Parameters/Flight Plan. The LiDAR system acquisition parameters were developed based on a...

Performance Evaluation and Opportunity Assessment for St. Bernard Project

Energy Technology Data Exchange (ETDEWEB)

Dickson, B.

2011-06-01

This report describes efforts by IBACOS, a Department of Energy Building America research team, in the St. Bernard Project, a nonprofit, community-based organization whose mission is to assist Hurricane Katrina survivors return to their homes in the New Orleans area. The report focuses on energy modeling results of two plans that the St. Bernard Project put forth as 'typical' building types and on quality issues that were observed during the field walk and Best Practice recommendations that could improve the energy efficiency and durability of the renovated homes.

Performance Evaluation and Opportunity Assessment for St. Bernard Project

Energy Technology Data Exchange (ETDEWEB)

Dickson, Bruce [IBACOS, Inc., Pittsburgh, PA (United States)

2011-06-01

This report describes efforts by IBACOS, a Building America research team, in the St. Bernard Project, a nonprofit, community-based organization whose mission is to assist Hurricane Katrina survivors to return to their homes in the New Orleans area. The report focuses on energy modeling results of two plans that the St. Bernard Project put forth as 'typical' building types and on quality issues that were observed during the field walk and best practice recommendations that could improve the energy efficiency and durability of the renovated homes.

Coal into the 21st century

International Nuclear Information System (INIS)

Beecy, D.J.

1991-01-01

The Plenary lecture to the conference addresses coal technologies with improved environmental performance to serve 21st century needs. The US DoE recognises the need for 'premium' processes for all stages of the fuel cycle. This has led to a research focus on fundamental science and technology

Cocaine use is associated with a higher prevalence of elevated ST2 concentrations.

Science.gov (United States)

van Wijk, Xander M R; Vittinghoff, Eric; Wu, Alan H B; Lynch, Kara L; Riley, Elise D

2017-09-01

Cocaine is a well-known risk factor for acute cardiac events, but the effects in users outside of acute events are less clear. We investigated a possible association between cocaine use and the concentration of a novel biomarker for cardiac stress and heart failure, ST2. A case-control study was conducted to compare ST2 concentrations by the presence of cocaine in patients presenting for care, but not cardiac care, at an urban safety net hospital. In samples taken from 100 cocaine-positive and 100 cocaine-negative patients, the presence of cocaine was associated with ST2 concentrations>35ng/mL. Serum concentrations of benzoylecgonine, a major cocaine metabolite, were significantly correlated with ST2 concentrations. Cocaine use is associated with subclinical cardiac stress and damage outside of acute cardiac events. This information could add to better stratification of cocaine users with elevated ST2 concentrations who may be at higher risk for developing heart failure and other cardiac complications. Copyright © 2017 The Canadian Society of Clinical Chemists. Published by Elsevier Inc. All rights reserved.

ST2 Deficiency Ameliorates High Fat Diet-Induced Liver Steatosis In BALB/c Mice

Directory of Open Access Journals (Sweden)

Jovicic Nemanja

2015-03-01

Full Text Available Non-alcoholic fatty liver disease (NAFLD is strongly associated with obesity, but the molecular mechanisms of liver steatosis and its progression to non-alcoholic steatohepatitis and fibrosis are incompletely understood. Immune reactivity plays an important role in the pathogenesis of NAFLD. The IL-33/ST2 axis has a protective role in adiposity and atherosclerosis, but its role in obesity-associated metabolic disorders requires further clarification. To investigate the unresolved role of IL-33/ST2 signalling in NAFLD, we used ST2-deficient (ST2-/- and wild type (WT BALB/c mice maintained on a high-fat diet (HFD for 24 weeks. HFD-fed ST2-/- mice exhibited increased weight gain, visceral adipose tissue weight and triglyceridaemia and decreased liver weight compared with diet-matched WT mice. Compared with WT mice on an HFD, ST2 deletion significantly reduced hepatic steatosis, liver inflammation and fibrosis and downregulated the expression of genes related to lipid metabolism in the liver. The frequency of innate immune cells in the liver, including CD68+ macrophages and CD11c+ dendritic cells, was lower in HFD-fed ST2-/- mice, accompanied by lower TNFα serum levels compared with diet-matched WT mice. Less collagen deposition in the livers of ST2-/- mice on an HFD was associated with lower numbers of profibrotic CD11b+Ly6clow monocytes and CD4+IL-17+ T cells in the liver, lower hepatic gene expression of procollagen, IL-33 and IL-13, and lower serum levels of IL-33 and IL-13 compared with diet-matched WT mice.

Case: Yritys X : henkilöstövaihtuvuuden syyt ja organisaatioon sitouttaminen

OpenAIRE

Jaatinen, Jenna

2017-01-01

Tämä opinnäytetyö on tehty yhteistyössä Yritys X:n kanssa ja aihe on valittu vastaamaan yrityksen tarpeita. Aiheeksi muodostui henkilöstön vaihtuvuuden syyt ja organisaatioon sitouttaminen, joka on rajattu Yritys X:n tavoitteiden mukaisesti. Heidän yksi neljästä tavoitteesta on saada vapaaehtoinen henkilöstövaihtuuvuus alle kymmeneen prosenttiin. Opinnäytetyön teoreettinen viitekehys käsittää vaihtuvuuden teoriaa yksilö- ja organisaatiotasolla sekä pitää sisällä olennaisia käsitteitä. Vi...

Sound velocity profiles in the St. Clair and St. Mary's Rivers in the Great Lakes area by the National Ocean Service's Navigation Response Team 4, May 2006 (NODC Accession 0006777)

Data.gov (United States)

National Oceanic and Atmospheric Administration, Department of Commerce — Sound velocity profile data were collected using sound velocimeter in the St. Clair and St. Mary rivers in the Great Lakes area by the NAVIGATION RESPONSE TEAM 4...

Clinical implications of anterior S-T segment depression in patients with acute inferior myocardial infarction

International Nuclear Information System (INIS)

Croft, C.H.; Woodward, W.; Nicod, P.; Corbett, J.R.; Lewis, S.E.; Willerson, J.T.; Rude, R.E.

1982-01-01

To assess various factors associated with anterior S-T segment depression during acute inferior myocardial infarction, 47 consecutive patients with electrocardiographic evidence of a first transmural inferior infarction were studied prospectively with radionuclide ventriculography an average of 7.3 hours (range 2.9 to 15.3) after the onset of symptoms. Thirty-nine patients (Group I) had anterior S-T depression in the initial electrocardiogram and 8 (Group II) did not have such reciprocal changes. There was no difference between the two groups in left ventricular end-diastolic or end-diastolic volume index or left ventricular ejection fraction. Stroke volume index was greater in Group I than in Group II. There were no group differences in left ventricular total or regional wall motion scores. A weak correlation existed between the quantities (mV) or inferior S-T segment elevation and reciprocal S-T depression. No relation between anterior S-T segment depression and the left ventricular end-diastolic volume index could be demonstrated; the extent of left ventricular apical and right ventricular wall motion abnormalities, both frequently associated with inferior infarction, did not correlate with the quantity of anterior S-T depression. These data show that anterior S-T segment depression occurs commonly during the early evolution of transmural inferior infarction, is not generally a marker of functionally significant anterior ischemia and cannot be used to predict left ventricular function in individual patients. Anterior S-T segment depression may be determined by reciprocal mechanisms

Efeito da utilização da somatotropina bovina recombinante (bST sobre a produção de leite em búfalas Effect of recombinant bovine somatotropin (bST utilization on milk production from buffaloes

Directory of Open Access Journals (Sweden)

André Mendes Jorge

2002-06-01

Full Text Available O objetivo deste trabalho foi estudar o resultado da utilização da somatotropina bovina recombinante (bST atuando na produção de leite em búfalas da raça Murrah. Empregaram-se 28 búfalas multíparas da raça Murrah, divididas em dois grupos homogêneos de 14 animais, recebendo os seguintes tratamentos: Grupo 1 ¾ Controle (solução salina e Grupo 2 ¾ 500 mg de bST/cabeça a cada 14 dias, durante 7 meses. Búfalas tratadas com bST exibiram incrementos de 48,52%, 32,80% e 32,80% nas produções total de leite, corrigida, depois, para 4% de gordura e média diária, respectivamente. A somatotropina elevou a produção total de gordura sem alterar a porcentagem dela no leite. A administração de bST não afetou a porcentagem de proteína do leite todavia, a produção total de proteína foi aumentada. Quanto à duração da lactação, o tratamento com bST diferiu do controle, o que demonstra a maior persistência da lactação de búfalas tratadas com bST.The objective of this work was to study the effect of recombinant bovine somatotropin (bST utilization on milk production from Murrah buffaloes. Twenty eight multiparous Murrah buffaloes were used and divided into two homogeneous groups of 14 animals, receiving the following treatments: Group 1 ¾ Control (salt solution and Group 2 ¾ 500 mg of bST/head every 14 days during 7 months. Buffaloes treated with bST presented increase of 48.52%, 32.80% and 32.80% on total milk yield, adjusted to 4% of fat and average daily milk yield, respectively. Somatotropin increased total fat milk yield without alter fat percentage of milk. Administration of bST did not affect protein percentage of milk while total protein milk yield increased. As for the lactating period, the treatment with bST differed of the control, what might have denoted in larger persistence of the lactation from buffaloes treated with bST.

Career Development and Social Inclusion at St Patrick's College: A Case Study

Science.gov (United States)

Hughes, Cathy

2010-01-01

Consistent with the Commonwealth government's social inclusion agenda, the mission statement of St Patrick's College advocates the development and delivery of career development services and programs that promote social justice and social inclusion. This case study describes the evolving career development program at St Patrick's College, which…

Windmill, sugar works, 'Springhall', St. Lucy, Barbados

OpenAIRE

Unknown

2003-01-01

204 x 143 mm. Showing the windmill and other refinery buildings with workers leading bullock teams loaded with cane towards the refinery. The Spring Hall Estate lies in the centre of St. Lucy Parish in northern Barbados.

ST Elevation in Lead aVR and Its Association with Clinical Outcomes

Directory of Open Access Journals (Sweden)

Eka Ginanjar

2018-01-01

Full Text Available The purpose of this case repots are to evaluate the role of ST elevation in aVR lead and to make analysis between both cases. There are some atypical electrocardiogram (ECG presentations which need prompt management in patient with ischemic clinical manifestation such as ST elevation in aVR lead. In this case study, we report a 68-year old woman with chief symptoms of shortness of breath and chest discomfort. She was diagnosed with cardiogenic shock, with Killip class IV, and TIMI score of 8. The second case is a 57-year-old man with typical chest pain at rest which could not be relieved with nitrate treatment. He was diagnosed with ST elevation in inferior and aVR lead, and occlusion in left circumflex artery (LCX. Both patients underwent primary percutaneous coronary intervention (PPCI. Subsequently, both cases presented remarkable clinical improvements and improved ST elevation myocardial infarction (STEMI in aVR lead.

The dissemination of ST80-SCCmec-IV community-associated methicillin resistant Staphylococcus aureus clone in Kuwait hospitals

Directory of Open Access Journals (Sweden)

Sarkhoo Eiman

2010-11-01

Full Text Available Abstract Background Community-associated methicillin-resistant Staphylococcus aureus (CA-MRSA is a global healthcare problem. The purpose of this study was to characterize CA-MRSA clones and their distribution in Kuwait hospitals. Methods In total, 135 CA-MRSA isolates, carrying the SCCmec IV or V genetic elements, isolated in eight hospitals were characterized using antibiogram, pulsed-field gel electrophoresis, multilocus sequence typing, and carriage of genes for Panton-Valentine Leukocidin (PVL, capsular polysaccharides types (cap 5 and 8, accessory genes regulators (agr, Staphylococcal enterotoxins (SE and toxic shock syndrome toxin 1 (tst. Results They were susceptible to vancomycin, teicoplanin and linezolid but resistant to kanamycin (62%, fusidic acid (42.2%, tetracycline (39.3%, erythromycin and clindamycin (21.5%, gentamicin (5.9%, streptomycin (6.7%, trimethoprim (5.9%, mupirocin (6.6% and cadmium acetate (82.2%. They consisted of 10 pulsotypes with the majority belonging to PFGE type I (51.1%, type II (22.2%, type IV (13.3% and type III (3.7%. They belonged to 10 sequence types (ST comprising ST80 (51.1%, ST30 (22.2%, ST5 (14.1%, ST1 (4.45, ST6 (3.7%, ST88 (1.5%, ST834 (1.5%, ST8 (0.7%, ST46 (0.7% and ST950 (0.7%. Genes for PVL, cap 8, cap 5 and agr III, agr I and agr II were detected in 61.5%, 77.3%, 20.7% and 62.2%, 17% and 8.1% of the isolates respectively. Nine (6.7% isolates contained tst while 103 isolates were positive for SE genes with sei (63.0%, seg (41.5% and sed (29.6% as the common SE genes. Conclusions ST80-SCCmecIV was the most common CA-MRSA clone in Kuwait hospitals presenting new challenges for infection control.

FHR patterns that become significant in connection with ST waveform changes and metabolic acidosis at birth.

Science.gov (United States)

Rosén, Karl G; Norén, Håkan; Carlsson, Ann

2018-04-18

Recent developments have produced new CTG classification systems and the question is to what extent these may affect the model of FHR + ST interpretation? The two new systems (FIGO2015 and SSOG2017) classify FHR + ST events differently from the current CTG classification system used in the STAN interpretation algorithm (STAN2007). Identify the predominant FHR patterns in connection with ST events in cases of cord artery metabolic acidosis missed by the different CTG classification systems. Indicate to what extent STAN clinical guidelines could be modified enhancing the sensitivity. Provide a pathophysiological rationale. Forty-four cases with umbilical cord artery metabolic acidosis were retrieved from a European multicenter database. Significant FHR + ST events were evaluated post hoc in consensus by an expert panel. Eighteen cases were not identified as in need of intervention and regarded as negative in the sensitivity analysis. In 12 cases, ST changes occurred but the CTG was regarded as reassuring. Visual analysis of the FHR + ST tracings revealed specific FHR patterns: Conclusion: These findings indicate FHR + ST analysis may be undertaken regardless of CTG classification system provided there is a more physiologically oriented approach to FHR assessment in connection with an ST event.

Childhood cancer mortality in relation to the St Lucie nuclear power station

International Nuclear Information System (INIS)

Boice, John D Jr; Mumma, Michael T; Blot, William J; Heath, Clark W Jr

2005-01-01

An unusual county-wide excess of childhood cancers of brain and other nervous tissue in the late 1990s in St Lucie County, Florida, prompted the Florida Department of Health to conduct a case-control study within the county assessing residential chemical exposures. No clear associations were found, but claims were then made that the release of radioactive substances such as strontium 90 from the St Lucie nuclear power station, which began operating in 1976, might have played a role. To test the plausibility of this hypothesis, we extended by 17 years a previous study of county mortality conducted by the National Cancer Institute. Rates of total cancer, leukaemia and cancer of brain and other nervous tissue in children and across all ages in St Lucie County were evaluated with respect to the years before and after the nuclear power station began operation and contrasted with rates in two similar counties in Florida (Polk and Volusia). Over the prolonged period 1950-2000, no unusual patterns of childhood cancer mortality were found for St Lucie County as a whole. In particular, no unusual patterns of childhood cancer mortality were seen in relation to the start-up of the St Lucie nuclear power station in 1976. Further, there were no significant differences in mortality between the study and comparison counties for any cancer in the time period after the power station was in operation. Relative rates for all childhood cancers and for childhood leukaemia were higher before the nuclear facility began operating than after, while rates of brain and other nervous tissue cancer were slightly lower in St Lucie County than in the two comparison counties for both time periods. Although definitive conclusions cannot be drawn from descriptive studies, these data provide no support for the hypothesis that the operation of the St Lucie nuclear power station has adversely affected the cancer mortality experience of county residents

Multi-Marker Strategy in Heart Failure: Combination of ST2 and CRP Predicts Poor Outcome.

Directory of Open Access Journals (Sweden)

Anne Marie Dupuy

Full Text Available Natriuretic peptides (BNP and NT-proBNP are recognized as gold-standard predictive markers in Heart Failure (HF. However, currently ST2 (member of the interleukin 1 receptor family has emerged as marker of inflammation, fibrosis and cardiac stress. We evaluated ST2 and CRP as prognostic markers in 178 patients with chronic heart failure in comparison with other classical markers such as clinical established parameters but also biological markers: NT-proBNP, hs-cTnT alone or in combination. In multivariate analysis, subsequent addition of ST2 led to age, CRP and ST2 as the only remaining predictors of all-cause mortality (HR 1.03, HR 1.61 and HR 2.75, respectively as well as of cardiovascular mortality (HR 1.00, HR 2.27 and HR 3.78, respectively. The combined increase of ST2 and CRP was significant for predicting worsened outcomes leading to identify a high risk subgroup that individual assessment of either marker. The same analysis was performed with ST2 in combination with Barcelona score. Overall, our findings extend previous data demonstrating that ST2 in combination with CRP as a valuable tool for identifying patients at risk of death.

Sediment Characterization in St. Alban's Bay, VT

Science.gov (United States)

Nethercutt, S.; Manley, T.; Manley, P.

2017-12-01

St. Alban's Bay within Lake Champlain is plagued with harmful algal blooms. With future intensification due to climate change, a multidisciplinary program (BREE-Basin Resilience to Extreme Events) was initiated in 2016. In order to assess the mobilization of harmful nutrients from sediment resuspension events and riverine input, 74 sediment samples were collected in a grid fashion throughout St. Alban's Bay. Sediments were deflocculated and analyzed using a LA920 Horiba laser scattering particle size distribution analyzer to define the frequency of sediment sizes from clay to sand. Gridded surfaces of mean sortable silt percentage, silt percentage, sand percentage, and clay percentage were used to represent the sediment distribution of the region. A plot of diameter versus frequency showed the bimodal nature of some of the sediments, with one peak at about 10 microns diameter (silt) and the second at about 525 microns diameter (sand). The data showed an extremely low percentage of clay relative to that of sand and silt. The highest frequencies of sortable silt, which represents the most easily mobilized particle size, are found in the deepest areas of the bay, suggesting that these regions are where dominant bottom flow occurs. The high occurrence of sortable silt in the St. Alban's Bay does suggest that sediment mobilization, and therefore nutrient mobilization has the potential to occur. These data combined with high-resolution multibeam and hydrodynamic data will allow for future models of water flow and remobilization studies in the future.

Caribbean ST Thomas trap Logbook Survey (Vessels)

Data.gov (United States)

National Oceanic and Atmospheric Administration, Department of Commerce — This data set contains catch (landed catch) and effort for fishing trips made by vessels fishing in St. Thomas. The catch and effort data for the entire trip are...

The electrocardiographic "triangular QRS-ST-T waveform" pattern in patients with ST-segment elevation myocardial infarction: Incidence, pathophysiology and clinical implications.

Science.gov (United States)

Cipriani, Alberto; D'Amico, Gianpiero; Brunello, Giulia; Perazzolo Marra, Martina; Migliore, Federico; Cacciavillani, Luisa; Tarantini, Giuseppe; Bauce, Barbara; Iliceto, Sabino; Corrado, Domenico; Zorzi, Alessandro

A specific ECG pattern of presentation of ST-segment elevation acute myocardial infarction (STEMI), characterized by "triangular QRS-ST-T waveform" (TW), has been associated with poor in-hospital prognosis but longitudinal data on its incidence and clinical impact are lacking. We prospectively evaluated the incidence and prognostic meaning of the TW pattern in a cohort of consecutive STEMI patients. All STEMI patients who presented within 12h of symptoms onset and showed no complete bundle branch block or paced ventricular rhythm were included. The TW pattern was defined as a unique, giant wave (amplitude≥1mV) resulting from the fusion of the QRS complex, the ST-segment and the T-wave and showing a "triangular" morphology with a positive polarity in the leads exploring the ischemic region. Among 428 consecutive STEMI patients, 367 fulfilled the enrollment criteria. The TW pattern was identified in 5 of 367 patients (1.4%) on the admission ECG. This subset of STEMI patients with TW pattern significantly more often showed a left main coronary artery involvement (2/4, 50% vs 2/322, 0.6%; p<0.001), experienced ventricular fibrillation (5/5, 100% vs 35/362, 9.6% p<0.001), had cardiogenic shock (4/5, 80% vs. 14/362, 3.8%, p<0.001) and died during hospitalization (2/5, 40% vs 15/362, 4.1% p=0.02), compared with those with other ST-segment elevation ECG patterns. The TW pattern is an uncommon ECG finding, which reflects the presence of a large area of transmural myocardial ischemia and predicts cardiogenic shock accounting for high in-hospital mortality. When present, this ECG pattern should prompt aggressive therapeutic strategies, including mechanical support of circulation. Copyright © 2017 Elsevier Inc. All rights reserved.

33 CFR 165.720 - Safety/Security Zone: St. Johns River, Jacksonville, FL.

Science.gov (United States)

2010-07-01

... 33 Navigation and Navigable Waters 2 2010-07-01 2010-07-01 false Safety/Security Zone: St. Johns... OF HOMELAND SECURITY (CONTINUED) PORTS AND WATERWAYS SAFETY REGULATED NAVIGATION AREAS AND LIMITED... § 165.720 Safety/Security Zone: St. Johns River, Jacksonville, FL. (a) Location. The water and the land...

Game based learning for 21st century transferable skills: challenges and opportunities

NARCIS (Netherlands)

Bellotti, Francesco; Bottino, Rosa Maria; Nadolski, Rob; Fernández Manjón, Baltasar

2012-01-01

Bellotti, F., Bottino, R. M., Nadolski, R. J., & Fernández Manjón, B. (2012, 4-6 July). Game based learning for 21st century transferable skills: challenges and opportunities. Presentation at the Workshop Game based learning for 21st century transferable skills: challenges and opportunities, 12th

78 FR 43064 - Safety Zone; Maritime Heritage Festival Fireworks, St. Helens, OR

Science.gov (United States)

2013-07-19

...-AA00 Safety Zone; Maritime Heritage Festival Fireworks, St. Helens, OR AGENCY: Coast Guard, DHS. ACTION... associated with fireworks displays. As part of the Maritime Heritage Festival Fireworks in St. Helens, OR, the festival will feature a fireworks display. The Coast Guard expects approximately 1,000 people to...

The Image of St Knud Lavard in his Liturgical Offices and its Historical Impact

DEFF Research Database (Denmark)

Petersen, Nils Holger

2015-01-01

The offices and masses of St Knud Lavard as preserved in a thirteenth-century manuscript, that was in itself probably a copy of the liturgy composed for the Feast of the Translation of St Knud Lavard in Ringsted Church on 25 June 1170, were edited by Professor John Bergsagel in 2010. Building...... on John Bergsagel’s commentary and findings and on other recent work on the liturgy of St Knud Lavard, a consideration of the texts, as well as the way the texts and music were composed together, forms the immediate background for this investigation of the image of St Knud Lavard as it is expressed...... and justice into the story of Knud Lavard and his personal cult. The historical impact of this image of St Knud in the sixteenth century and its reappropriation for a notion of national identity in the nineteenth century, as well as in different ways in more recent times, is also examined....

Gallbladder Cancer in the 21st Century

Directory of Open Access Journals (Sweden)

Rani Kanthan

2015-01-01

Full Text Available Gallbladder cancer (GBC is an uncommon disease in the majority of the world despite being the most common and aggressive malignancy of the biliary tree. Early diagnosis is essential for improved prognosis; however, indolent and nonspecific clinical presentations with a paucity of pathognomonic/predictive radiological features often preclude accurate identification of GBC at an early stage. As such, GBC remains a highly lethal disease, with only 10% of all patients presenting at a stage amenable to surgical resection. Among this select population, continued improvements in survival during the 21st century are attributable to aggressive radical surgery with improved surgical techniques. This paper reviews the current available literature of the 21st century on PubMed and Medline to provide a detailed summary of the epidemiology and risk factors, pathogenesis, clinical presentation, radiology, pathology, management, and prognosis of GBC.

The effects of dominance, regular inbreeding and sampling design on Q(ST), an estimator of population differentiation for quantitative traits.

Science.gov (United States)

Goudet, Jérôme; Büchi, Lucie

2006-02-01

To test whether quantitative traits are under directional or homogenizing selection, it is common practice to compare population differentiation estimates at molecular markers (F(ST)) and quantitative traits (Q(ST)). If the trait is neutral and its determinism is additive, then theory predicts that Q(ST) = F(ST), while Q(ST) > F(ST) is predicted under directional selection for different local optima, and Q(ST) sampling designs and find that it is always best to sample many populations (>20) with few families (five) rather than few populations with many families. Provided that estimates of Q(ST) are derived from individuals originating from many populations, we conclude that the pattern Q(ST) > F(ST), and hence the inference of directional selection for different local optima, is robust to the effect of nonadditive gene actions.

ST2 is essential for Th2 responsiveness and resistance to pseudomonas aeruginosa keratitis.

Science.gov (United States)

Huang, Xi; Du, Wenjin; Barrett, Ronald P; Hazlett, Linda D

2007-10-01

To elucidate the role of ST2, a member of the TLR/IL-1R (TIR) superfamily, in protecting against Pseudomonas aeruginosa keratitis in BALB/c mice. ST2 mRNA and protein expression levels were tested by real-time PCR and Western-blot in C57BL/6 (B6; susceptible) versus BALB/c (resistant) mice before and after P. aeruginosa (strain 19660; American Type Culture Collection, Philadelphia, PA) challenge. Infected BALB/c mice also were tested after subconjunctival injection with recombinant murine (rm)ST2 or PBS. Disease was monitored by clinical score, slit lamp, bacterial plate count, a myeloperoxidase (MPO) assay to measure polymorphonuclear neutrophil (PMN) infiltrate, real-time RT-PCR, and ELISA. ST2 mRNA and protein were constitutively expressed in the uninfected normal corneas of both mouse groups. ST2 levels in the cornea of BALB/c compared with B6 mice were elevated significantly at 1 to 3 days post infection (PI), peaked at 3 and decreased at 5 days PI. BALB/c mice treated with rmST2 showed increased corneal opacity and perforation (at 5 days PI) when compared with PBS controls. rmST2- versus PBS-injected mice exhibited increased bacterial load, PMN infiltrate, and higher corneal mRNA levels for IL-1beta, MIP-2, IL-6, IL-1R1, and Th1-type cytokine such as IFN-gamma. Protein levels for IL-1beta, MIP-2, and IL-6 also were significantly upregulated, whereas the Th2 cytokines IL-4 (mRNA), IL-5 (mRNA), and IL-10 (mRNA and protein) were significantly reduced. ST2 is critical in resistance to P. aeruginosa keratitis, functioning to reduce corneal infection (bacterial load) and inflammation by negatively regulating proinflammatory cytokines and inhibiting type-1 immunity, but upregulating type-2 cytokine production, particularly IL-10.

On the History of the Publication of the Menaion Reader by Demetrius of Rostov (the Text On the Year of Death of St. Mary of Egypt as an Additional Article to the Menaion Reader by St. Demetrius

Directory of Open Access Journals (Sweden)

Marina A. Fedotova

2015-08-01

The author of the present paper makes available a new, unknown, and unpublished work by St. Demetrius of Rostov, On the Year of Death of St. Mary of Egypt, which was written as an additional calendar text referring to the Life of St. Mary of Egypt. The sources of the Life of St. Mary of Egypt were the Acta Sanctorum and De Probatis Sanctorum Historiis by Laurentius Surius. The text On the Year of Death of St. Mary of Egypt was written by Demetrius for the first edition, but it was not included in the printed edition and is preserved only in manuscript sources.

Making sense of Mount St. Helens

Science.gov (United States)

Steve Nash

2010-01-01

The eruption of Mount St. Helens in 1980 resulted in "a grand experiment that you could never have gotten anybody to fund," says Forest Service ecologist Charles Crisafulli. "Everything's new. It's a new landform." Unlike most misbehaving volcanoes, this one provided an accessible laboratory right along the Interstate-5 corridor, with the...

33 CFR 207.440 - St. Marys Falls Canal and Locks, Mich.; use, administration, and navigation.

Science.gov (United States)

2010-07-01

... 33 Navigation and Navigable Waters 3 2010-07-01 2010-07-01 false St. Marys Falls Canal and Locks... CORPS OF ENGINEERS, DEPARTMENT OF THE ARMY, DEPARTMENT OF DEFENSE NAVIGATION REGULATIONS § 207.440 St... include all of the natural waters of the St. Marys River on the U.S. side of the International Boundary...

[National Consultant in Cardiology Experts' Group Guidelines on dealing with patients implanted with some St. Jude Medical Riata and Riata ST leads].

Science.gov (United States)

Mitkowski, Przemysław; Grabowski, Marcin; Kowalski, Oskar; Kutarski, Andrzej; Mojkowski, Włodzimierz; Przybylski, Andrzej; Sterliński, Maciej; Trusz-Gluza, Maria; Opolski, Grzegorz

2014-01-01

In December 2010 St. Jude Medical informed about higher incidence of silicone insulation abrasion in implantable cardioverter-defibrillator leads Riata/Riata ST. The manifestation of this phenomenon is the externalisation of conductors outside the body of the lead, which is visible in a fluoroscopy. The abrasion could also involve an insulation under high-voltage coil and in the worst case could result in a short circuit within high voltage part of the system. The incidence of this phenomenon varies from part of to several dozen percent according to published papers and becomes higher in a longer follow-up. The highest probability of malfunction in 8 F single coil and the lowest in 7 F dual-coil leads is observed. For the needs of this guidelines all Riata/Riata ST leads were divided into: functioning, damaged but active (visible externalisation but electrically functioning), malfunctioning. In the last case the lead should be removed and a new one implanted (class of indication I) ,although only implantation of a new lead with abandoning malfunctioning one is allowed and should be considered (IIa). In patients with functioning lead extraction with a new lead implantation may be considered during elective replacement only in high risk patients (IIb). In case of damaged but active lead its extraction with the implantation of a new lead during elective replacement of the device should be considered in high risk population (IIa) and may be considered in other patients (IIb). The final decision related to Riata/Riata ST should be individualised and undertaken in co-operation with the patient after detailed assessment of the risk related to each treatment option.

Role of Soluble ST2 as a Marker for Rejection after Heart Transplant.

Science.gov (United States)

Lee, Ga Yeon; Choi, Jin-Oh; Ju, Eun-Seon; Lee, Yoo-Jung; Jeon, Eun-Seok

2016-11-01

Endomyocardial biopsy is obligatory during the first year after heart transplant (HTx) for the surveillance of acute rejection. Previous attempts using cardiac biomarkers for the detection of rejection failed to show enough evidence to substitute endomyocardial biopsy. Therefore, this study sought the possibility of using soluble ST2 (sST2), a novel cardiovascular marker, as a surrogate marker for acute allograft rejection after HTx. A total of 494 blood samples acquired at the time of endomyocardial biopsy were analyzed in 67 HTx cases from September 2006 to August 2014. Significant rejection was defined as International Society of Heart and Lung Transplant (ISHLT) score ≥2R and humoral rejection accompanied by hemodynamic instability. Twenty cases of HTx with 22 blood samples showed significant rejection in endomyocardial biopsy at 4.0 (2.0-9.0) months after HTx. The level of sST2 showed positive correlation with cardiac troponin I, and N-terminal pro-B-type natriuretic peptide (all prejection) (p=0.003). However, when we studied within-subject effects of sST2 using a mixed model, the sST2 level according to the predefined time point was not different according to the presence of significant rejection (p for interaction=0.94). Although sST2 is known as a promising predictor for cardiovascular events, its role in HTx patients to predict acute allograft rejection seems to be limited.

4CaaSt : Comprehensive management of Cloud services through a PaaS

NARCIS (Netherlands)

Garcia-Gomez, S.; Lelli, F.; Eschriche-Vicente, M.; Arozarena-Llopis, P.; Taher, Y.; Momm, C.; Spriestersbach, A.; Jimenez-Ganan, M.; Le Jeune, G.; Dao, M.; Carrie, S.P.; Niemoller, J.; Mazmanov, D.; Biro, J.; Giesmann, A.; Junker, F.

2012-01-01

The 4CaaSt project aims at developing a PaaS framework that enables flexible definition, marketing, deployment and management of Cloud-based services and applications. The major innovations proposed by 4CaaSt are the blueprint and its lifecycle management, a one stop shop for Cloud services and a

Physical medicine and rehabilitation in the 21st century.

Science.gov (United States)

Reinstein, L

1994-01-01

In conclusion, physical medicine and rehabilitation in the 21st century will be: new, exciting technologies, different patient populations, different practice settings, fewer PM&R residents, and more physician assistants, all operating under a universal access, single payer, Canadian-style health care system. I began my presentation with a quote from Yogi Berra. I'll close by paraphrasing the immortal words of Charles Dickens in the opening lines of A Tale Of Two Cities. PM&R in the 21st century will be "the best of times, the worst of times, the epoch of belief, the epoch of incredulity."

Rwanda. Dansk støtte er en god investering

DEFF Research Database (Denmark)

Larsen, Josefine Kühnel

2012-01-01

Danmark fortsætter militær støtte til Rwanda mens andre lande fryser bistand Rwandas regering har siden 2005 bidraget betydeligt til fredsbevarende operationer. Rwanda har gennem sit styrkebidrag til fredsbevarende operationer potentialet til at spille en væsentlig regional rolle pga. landets...... militære styrke og erfaring med forsoning, konfliktløsning og genopbygning efter krigen og folkemordet i 1994. Aktuelt bidrager Rwanda med 4,577 soldater til fredsbevarende missioner i FN-regi, hvilket betyder, at Rwanda er det land i verden, der leverer det sjette største militære styrkebidrag til FN...

76 FR 39890 - St. Johns National Wildlife Refuge, FL; Draft Comprehensive Conservation Plan and Environmental...

Science.gov (United States)

2011-07-07

... DEPARTMENT OF THE INTERIOR Fish and Wildlife Service [FWS-R4-R-2011-N053; 40136-1265-0000-S3] St... conservation plan and environmental assessment (Draft CCP/EA) for St. Johns National Wildlife Refuge (NWR) in... Complex, P.O. Box 2683, Titusville, FL 32781, or via e-mail at [email protected] , or St. Johns CCP...

A Case Study of 21st Century Skills in High Achieving Elementary Schools in Pennsylvania

Science.gov (United States)

Egnor, Gregory P.

2013-01-01

This study examines if practices that advocate for 21st century skills are in conflict with the mandates of NCLB. Interviews with influential school leaders of high achieving elementary schools focused on collecting data about 21st century skills. This study was designed to (a) Determine if 21st century skills are addressed in high achieving…

Genome sequencing and molecular characterisation of Staphylococcus aureus ST772-MRSA-V, "Bengal Bay Clone".

Science.gov (United States)

Monecke, Stefan; Baier, Vico; Coombs, Geoffrey W; Slickers, Peter; Ziegler, Albrecht; Ehricht, Ralf

2013-12-20

The PVL-positive ST772-MRSA-V is an emerging community-associated (CA-) MRSA clone that has been named Bengal Bay Clone since most patients have epidemiological connections to the Indian subcontinent. It is found increasingly common in other areas of the world. One isolate of ST772-MRSA-V was sequenced using the Illumina Genome Analyzer System. After initial assembling the multiple sequence contigs were analysed using different in-house annotation scripts. Results were compared to microarray hybridisation results of clinical isolates of ST772-MRSA-V, of related strains and to another ST772-MRSA-V genome sequence. According to MLST e-burst analysis, ST772-MRSA-V belongs to Clonal Complex (CC)1, differing from ST1 only in one MLST allele (pta-22). However, there are several additional differences including agr alleles (group II rather than III), capsule type (5 rather than 8), the presence of the egc enterotoxin gene cluster and of the enterotoxin homologue ORF CM14 as well as the absence of the enterotoxin H gene seh. Enterotoxin genes sec and sel are present. ST772-MRSA-V harbours the genes encoding enterotoxin A (sea) and PVL (lukS/F-PV). Both are located on the same prophage. ST772-MRSA-V may have emerged from the same lineage as globally spread CC1 and CC5 strains. It has acquired a variety of virulence factors, and for a CA-MRSA strain it has an unusually high number of genes associated with antibiotic resistance.

Bathymetry (2011) for Fish Bay, St. John

Data.gov (United States)

National Oceanic and Atmospheric Administration, Department of Commerce — This image represents a LiDAR (Light Detection & Ranging) 0.3x0.3 meter resolution depth surface for Fish Bay, St. John in the U.S. Virgin Islands (USVI). The...

Bathymetry (2011) for Coral Bay, St. John

Data.gov (United States)

National Oceanic and Atmospheric Administration, Department of Commerce — This image represents a LiDAR (Light Detection & Ranging) 0.3x0.3 meter resolution depth surface for Coral Bay, St. John in the U.S. Virgin Islands (USVI). The...

Progressive epicardial coronary blood flow reduction fails to produce ST-segment depression at normal heart rates.

Science.gov (United States)

de Chantal, Marilyn; Diodati, Jean G; Nasmith, James B; Amyot, Robert; LeBlanc, A Robert; Schampaert, Erick; Pharand, Chantal

2006-12-01

ST-segment depression is commonly seen in patients with acute coronary syndromes. Most authors have attributed it to transient reductions in coronary blood flow due to nonocclusive thrombus formation on a disrupted atherosclerotic plaque and dynamic focal vasospasm at the site of coronary artery stenosis. However, ST-segment depression was never reproduced in classic animal models of coronary stenosis without the presence of tachycardia. We hypothesized that ST-segment depression occurring during acute coronary syndromes is not entirely explained by changes in epicardial coronary artery resistance and thus evaluated the effect of a slow, progressive epicardial coronary artery occlusion on the ECG and regional myocardial blood flow in anesthetized pigs. Slow, progressive occlusion over 72 min (SD 27) of the left anterior descending coronary artery in 20 anesthetized pigs led to a 90% decrease in coronary blood flow and the development of ST-segment elevation associated with homogeneous and transmural myocardial blood flow reductions, confirmed by microspheres and myocardial contrast echocardiography. ST-segment depression was not observed in any ECG lead before the development of ST-segment elevation. At normal heart rates, progressive epicardial stenosis of a coronary artery results in myocardial ischemia associated with homogeneous, transmural reduction in regional myocardial blood flow and ST-segment elevation, without preceding ST-segment depression. Thus, in coronary syndromes with ST-segment depression and predominant subendocardial ischemia, factors other than mere increases in epicardial coronary resistance must be invoked to explain the heterogeneous parietal distribution of flow and associated ECG changes.

Entomologic studies after a St. Louis encephalitis epidemic in Grand Junction, Colorado.

Science.gov (United States)

Tasi, T F; Smith, G C; Ndukwu, M; Jakob, W L; Happ, C M; Kirk, L J; Francy, D B; Lampert, K J

1988-08-01

In 1986, after a St. Louis encephalitis epidemic in Grand Junction, Colorado, in 1985, vector mosquitoes in the city were surveyed to correlate their bionomics and infection rates with the occurrence of human disease. No human cases were reported, but mosquito surveillance disclosed St. Louis encephalitis virus in Culex tarsalis and Culex pipiens pipiens. Mosquitoes were collected with gravid traps designed to attract Cx. p. pipiens and with Centers for Disease Control light traps. Culex p. pipiens was the predominant vector mosquito collected and was captured chiefly in gravid traps. The Culex tarsalis population emerged and expanded approximately one month earlier than did the Cx. p. pipiens population. Consequently, Cx. p. pipiens was the predominant vector species after August. Infection rates throughout the surveillance period (June to September) were severalfold higher in Cx. tarsalis than in Cx. p. pipiens; however, in late summer, diminished numbers of Cx. tarsalis and a persistent population of Cx. p. pipiens resulted in relatively larger numbers of infected Cx. p. pipiens. Thus, the participation of Cx. p. pipiens as a St. Louis encephalitis vector would have been underestimated in previous studies employing light traps alone. These studies provide further evidence that Cx. p. pipiens-associated urban St. Louis encephalitis and rural Cx. tarsalis-associated St. Louis encephalitis cycles may coexist in the West.

Automated system for ST segment and arrhythmia analysis in exercise radionuclide ventriculography

International Nuclear Information System (INIS)

Hsia, P.W.; Jenkins, J.M.; Shimoni, Y.; Gage, K.P.; Santinga, J.T.; Pitt, B.

1986-01-01

A computer-based system for interpretation of the electrocardiogram (ECG) in the diagnosis of arrhythmia and ST segment abnormality in an exercise system is presented. The system was designed for inclusion in a gamma camera so the ECG diagnosis could be combined with the diagnostic capability of radionuclide ventriculography. Digitized data are analyzed in a beat-by-beat mode and a contextual diagnosis of underlying rhythm is provided. Each beat is assigned a beat code based on a combination of waveform analysis and RR interval measurement. The waveform analysis employs a new correlation coefficient formula which corrects for baseline wander. Selective signal averaging, in which only normal beats are included, is done for an improved signal-to-noise ratio prior to ST segment analysis. Template generation, R wave detection, QRS window size, baseline correction, and continuous updating of heart rate have all been automated. ST level and slope measurements are computed on signal-averaged data. Arrhythmia analysis of 13 passages of abnormal rhythm by computer was found to be correct in 98.4 percent of all beats. 25 passages of exercise data, 1-5 min in length, were evaluated by the cardiologist and found to be in agreement in 95.8 percent in measurements of ST level and 91.7 percent in measurements of ST slope

ST Elevations and Elevated Cardiac Enzymes Not Always a STEMI: Two Case Reports.

Science.gov (United States)

Fernández Fernández, Juan; Deliz-Guzmán, Claudia; Andino-Colón, César; Claudio-Hernández, Héctor; Lugo-Amador, Nannette

2016-01-01

Chest pain is a common complaint in the emergency department (ED). Besides a careful history and physical exam; electrocardiogram, laboratory tests and imaging studies are widely available diagnostic tests that are used for patient assessment. When ST elevation and elevated cardiac enzymes are present the most likely diagnosis are ST elevation myocardial infarction (STEMI) or myocarditis. In this case report we present two low risk patients for major adverse cardiac event with ST elevation and elevated cardiac enzymes and how a careful risk assessment and detailed electrocardiogram evaluation could help differentiating between these two diagnoses.

Influence of soil on St3 surface spectroscopic characteristics under cathode protection conditions

International Nuclear Information System (INIS)

Kuznetsova, E.G.; Lazorenko-Manevich, R.M.; Sokolova, L.A.; Remezkova, L.V.

1992-01-01

Using electroreflection spectra it is shown, that St3 surface following long holding in cold clay without cathode protection is less heterogeneous relative to water absorption, than surface of initial specimens, as well as, of specimens holded in wet clay. This variation of distribution of adsorption centres by heats of water absorption results from stable absorption of surface-and-active components of clayed soil and is accompanied by increase of St3 corrosion stability. Long-term cathode polarization reduces initial distribution and decreases corrosion stability of St3

Eesti goes St. Etienne / Anna Roomet

Index Scriptorium Estoniae

Roomet, Anna

2006-01-01

Näitus Eesti Kunstiakadeemia tootedisaini osakonna magistrantide viimase kahe aasta projektide paremikust esindas Eestit disainibiennaalil St. Etiennis Prantsusmaal. Näituse panid üles Pent Talvet ja Pavel Sidorenko, näitusel osalejad: Anna-Maria Einla, Kätlin Kangur, Triin Kuusler, Andri Laidre, Veiko Liis, Liina-Kai Raivet, P. Sidorenko, P. Talvet, Ingela Viks, Triin Voss

Genomic Analysis of Multidrug-Resistant Escherichia coli from North Carolina Community Hospitals: Ongoing Circulation of CTX-M-Producing ST131-H30Rx and ST131-H30R1 Strains.

Science.gov (United States)

Kanamori, Hajime; Parobek, Christian M; Juliano, Jonathan J; Johnson, James R; Johnston, Brian D; Johnson, Timothy J; Weber, David J; Rutala, William A; Anderson, Deverick J

2017-08-01

Escherichia coli sequence type 131 (ST131) predominates globally among multidrug-resistant (MDR) E. coli strains. We used whole-genome sequencing (WGS) to investigate 63 MDR E. coli isolates from 7 North Carolina community hospitals (2010 to 2015). Of these, 39 (62%) represented ST131, including 37 (95%) from the ST131- H 30R subclone: 10 (27%) from its H 30R1 subset and 27 (69%) from its H 30Rx subset. ST131 core genomes differed by a median of 15 (range, 0 to 490) single-nucleotide variants (SNVs) overall versus only 7 within H 30R1 (range, 3 to 12 SNVs) and 11 within H 30Rx (range, 0 to 21). The four isolates with identical core genomes were all H 30Rx. Epidemiological and clinical characteristics did not vary significantly by strain type, but many patients with MDR E. coli or H 30Rx infection were critically ill and had poor outcomes. H 30Rx isolates characteristically exhibited fluoroquinolone resistance and CTX-M-15 production, had a high prevalence of trimethoprim-sulfamethoxazole resistance (89%), sul1 (89%), and dfrA17 (85%), and were enriched for specific virulence traits, and all qualified as extraintestinal pathogenic E. coli The high overall prevalence of CTX-M-15 appeared to be possibly attributable to its association with the ST131- H 30Rx subclone and IncF[F2:A1:B-] plasmids. Some phylogenetically clustered non-ST131 MDR E. coli isolates also had distinctive serotypes/ fimH types, fluoroquinolone mutations, CTX-M variants, and IncF types. Thus, WGS analysis of our community hospital source MDR E. coli isolates suggested ongoing circulation and differentiation of E. coli ST131 subclones, with clonal segregation of CTX-M variants, other resistance genes, Inc-type plasmids, and virulence genes. Copyright © 2017 American Society for Microbiology.

Characteristics related to antimicrobial resistance and biofilm formation of widespread methicillin-resistant Staphylococcus epidermidis ST2 and ST23 lineages in Rio de Janeiro hospitals, Brazil.

Science.gov (United States)

Iorio, Natalia Lopes Pontes; Caboclo, Roberta Ferreira; Azevedo, Milena Borgo; Barcellos, Ariane Guimarães; Neves, Felipe Piedade Gonçalves; Domingues, Regina Maria Cavalcanti Pilotto; dos Santos, Kátia Regina Netto

2012-01-01

Staphylococcus epidermidis is a leading cause of hospital-acquired infections, mostly associated with the use of medical devices in seriously ill or immunocompromised patients. Currently, the characteristics of methicillin-resistant S. epidermidis (MRSE) isolates from Rio de Janeiro hospitals are unknown. In this study, staphylococcal chromosomal cassette mec (SCCmec) types, antimicrobial susceptibility profiles, biofilm formation genes, and multilocus sequence types (MLST) were investigated in 35 MRSE clinical isolates. The collection of isolates was previously well characterized by pulsed-field gel electrophoresis (PFGE) into 2 main genotypes (A and B, 22 isolates) and 10 sporadic genotypes (13 isolates). MLST revealed a total of 8 different sequence types (STs), but ST2 and ST23, which were icaAB-positive, represented the majority (71.4%) of MRSE isolates tested. Almost all isolates (91.4%) belonged to clonal complex 2. SCCmec types III and IV were identified among 71.4% of the isolates, while the remaining was nontypeable. The predominant MRSE genotypes were defined as SCCmec type III/ST2 (PFGE type A) and SCCmec type IV/ST23 (PFGE type B) isolates, which were both associated with high antimicrobial resistance and presence of biofilm-related genes. Copyright © 2012 Elsevier Inc. All rights reserved.

A comparative analysis of international frameworks for 21st century competences: implications for national curriculum policies

NARCIS (Netherlands)

Voogt, Joke; Pareja Roblin, N.N.

2012-01-01

National curricula need to change drastically to comply with the competences needed for the 21st century. In this paper eight frameworks describing 21st century competences were analysed. A comprehensive search for information about 21st century competences was conducted across the official websites

Comparative Genomic Analysis of Globally Dominant ST131 Clone with Other Epidemiologically Successful Extraintestinal Pathogenic Escherichia coli (ExPEC Lineages

Directory of Open Access Journals (Sweden)

Sabiha Shaik

2017-10-01

Full Text Available Escherichia coli sequence type 131 (ST131, a pandemic clone responsible for the high incidence of extraintestinal pathogenic E. coli (ExPEC infections, has been known widely for its contribution to the worldwide dissemination of multidrug resistance. Although other ExPEC-associated and extended-spectrum-β-lactamase (ESBL-producing E. coli clones, such as ST38, ST405, and ST648 have been studied widely, no comparative genomic data with respect to other genotypes exist for ST131. In this study, comparative genomic analysis was performed for 99 ST131 E. coli strains with 40 genomes from three other STs, including ST38 (n = 12, ST405 (n = 10, and ST648 (n = 18, and functional studies were performed on five in-house strains corresponding to the four STs. Phylogenomic analysis results from this study corroborated with the sequence type-specific clonality. Results from the genome-wide resistance profiling confirmed that all strains were inherently multidrug resistant. ST131 genomes showed unique virulence profiles, and analysis of mobile genetic elements and their associated methyltransferases (MTases has revealed that several of them were missing from the majority of the non-ST131 strains. Despite the fact that non-ST131 strains lacked few essential genes belonging to the serum resistome, the in-house strains representing all four STs demonstrated similar resistance levels to serum antibactericidal activity. Core genome analysis data revealed that non-ST131 strains usually lacked several ST131-defined genomic coordinates, and a significant number of genes were missing from the core of the ST131 genomes. Data from this study reinforce adaptive diversification of E. coli strains belonging to the ST131 lineage and provide new insights into the molecular mechanisms underlying clonal diversification of the ST131 lineage.

ST Implications in the CNGS Project

CERN Document Server

Wilhelmsson, M

2000-01-01

The CNGS project concerns the construction of a neutrino beam facility (CNGS = CERN Neutrino beam to Gran Sasso). A 450 GeV proton beam will be extracted from the SPS accelerator. This proton beam will hit a target a few hundred metres downstream from the extraction point (BA4). In the debris of the proton beam we will find pions which continue down a 1000 m, evacuated tunnel and a fraction of which decay into a neutrino beam. After this decay tunnel (1.1 km), a 'hadron stop' will separate the neutrinos, after which they will resume their journey down to a detector pit, outside Rome (Gran Sasso). The CERN facility has a total length of approximately 3 km. The ST division has an important share in the construction work, both of the above-mentioned tunnels as well as of all other infrastructure services, and this work concerns most of the groups in the division. This report will outline the technical design of the facility and explain how we, in the ST division, are involved in the project. The CERN council app...

Retendering of ST-CV maintenance contract

CERN Document Server

Battistin, M

2003-01-01

During the next three years, the ST/CV group will be deeply involved in the installation works for the LHC project. During this period the need for maintenance activity will decrease. The minimum level will be reached during the “long shutdown” of the PS and SPS machines in 2005. The budget for the maintenance will decrease accordingly, thus the CV group had to review its maintenance strategy. The new contract, which started on January 1st 2003, has been defined to cope with these workload variations during the next years and to guarantee the minimum maintenance activity on the existing equipment. A lump-sum contract based on a win-win strategy has been discarded. The contractor no longer has to guarantee the performance of the CERN cooling and ventilation systems. A new price list strategy based on performance indicators and penalties has been chosen. The contractor now has to guarantee the performance of every maintenance operation demanded by CERN. This modification obliged the Operation section of the...

Special report: Mt. St. Helens

Science.gov (United States)

Mt. St Helens Volcano, Cascade Range, Southern Washington, USA (46.20°N, 122.18°W.) All times are local (GMT - 7 h through October 24, GMT - 8 h thereafter. Lava extrusion that probably began October 30 added a new lobe to the composite dome in the crater of Mt. St. Helens. After lava extrusion ended September 10 (see September 22 Eos), rates of deformation in the crater remained low for several weeks, as they had after earlier extrusion episodes. Sulfur dioxide emission ranged from 70 to 190 tons per day between October 9 and 24, but showed no particular trends. Inflation of the dome has caused small thrust faults to form in the surrounding crater floor. In early October the most active thrust, south of the dome, was moving at about 1.5 cm/d, and stations on the north crater rampart showed outward movement of about 0.5 cm/d. By October 24 these rates had increased to 14.5 and 3.5-4 cm/d, respectively, and leveling profiles perpendicular to the dome showed that crater floor tilt rates had reached 400-500 μrad/d, prompting the U.S. Geological Survey (USGS) to issue an advisory prediction of renewed lava extrusion within the next two weeks.

Bigeminy: A result of digoxin and St John’s wort interaction

Directory of Open Access Journals (Sweden)

Anđelić Slađana

2003-01-01

Full Text Available A case of an by digoxin under unusual circumstances is reported. An 80-year-old man, previously on long-term digoxin treatment, started consuming St John’s wort herbal tea (2 000 ml/daily because of frequent episodes of depression. After the cessation of consuming herbal tea containing Hypericum perforatum, digoxin poisoning developed in our patient. Electrocardiography revealed nodal bradicardia 36/min and bigeminy. Manifested symptoms were the consequence of interaction between digoxin and Hypericum perforatum which were consumed simultaneously, and the cessation of consuming St John’s wort herbal tea afterwards. Therapy was the same as in the standard digitalis poisoning. Consumers of St John’s wort combined with medical products are advised not to discontinue tea consumption on their own, without consulting their physician.

Calibration of HERS-ST for estimating traffic impact on pavement deterioration in Texas.

Science.gov (United States)

2012-08-01

The Highway Economic Requirements System-State Version (or the HERS-ST) is a software package which was developed by the Federal Highway Administration as a tool for evaluating the performance of state highway systems. HERS-ST has the capabilities of...

78 FR 7387 - Advisory Committee on Biotechnology and 21st Century Agriculture; Renewal

Science.gov (United States)

2013-02-01

...;and investigations, committee meetings, agency decisions and rulings, #0;delegations of authority... Biotechnology and 21st Century Agriculture; Renewal AGENCY: Agricultural Research Service, USDA. ACTION: Advisory Committee on Biotechnology and 21st Century Agriculture Renewal. SUMMARY: Notice is hereby given...

Impact of metabolic syndrome on ST segment resolution after thrombolytic therapy for acute myocardial infarction

Directory of Open Access Journals (Sweden)

Ayşe Saatçı Yaşar

2010-09-01

Full Text Available Objectives: It has been shown that metabolic syndrome is associated with poor short-term outcome and poor long-term survival in patients with acute myocardial infarction. We aimed to investigate the effect of metabolic syndrome on ST segment resolution in patients received thrombolytic therapy for acute myocardial infarction.Materials and methods: We retrospectively analyzed 161 patients, who were admitted to our clinics with acute ST-elevated-myocardial infarction and received thrombolytic therapy within 12 hours of chest pain. Metabolic syndrome was diagnosed according to National Cholesterol Education Program Adult Treatment Panel III criteria. Resolution of ST segment elevation was assessed on the baseline and 90-minute electrocardiograms. ST segment resolution ≥70% was defined as complete resolution.Results: Metabolic syndrome was found in 56.5% of patients. The proportion of patients with metabolic syndrome who achieved complete ST segment resolution after thrombolysis was significantly lower than that of patients without metabolic syndrome (32.9% versus 58.6%, p=0.001. On multivariate analysis metabolic syndrome was the only independent predictor of ST segment resolution (p=0.01, Odds ratio=2.543, %95 CI:1.248-5.179Conclusion: The patients with metabolic syndrome had lower rates of complete ST segment resolution after thrombolytic therapy for acute myocardial infarction. This finding may contribute to the higher morbidity and mortality of patients with metabolic syndrome.

Energetic evaluation of indigenous tree and shrub species in Basilicata, Southern Italy

Directory of Open Access Journals (Sweden)

Todaro L

2007-01-01

Full Text Available An evaluation of energetic characteristics such as high calorific value (on ash-free dry weight basis, ash, carbon, nitrogen, and moisture content of 12 indigenous tree and shrub species of Southern Italy (Basilicata Region was carried out. The studied species are the most abundant in this area: Quercus cerris L., Quercus pubescens Willd., Fraxinus ornus L., Populus canescens (Aiton Smith, Salix alba L., Alnus cordata L., Robinia pseudoacacia L., Olea europaea L., Spartium junceum L., Rubus hirtus W., Onopordum illirium L., Arundo donax L. For Q. cerris, Q. pubescens and O. europaea L., the energetic characteristics were measured by separating the wood components from the leaves. Q. cerris leaves contained the greatest high calorific value. F. ornus leaves had a greater ash content than the other samples while the lowest values were measured for S. junceum, Q. pubescens and R. pseudoacacia. The highest content of Carbon was in O. europaea leaves. A. donax and O. illirium had the lower level of high calorific value and Carbon than all the other species. The highest Nitrogen content was measured in Q. cerris leaves and the lowest one in F. ornus wood components.

Smart Social Networking: 21st Century Teaching and Learning Skills

Directory of Open Access Journals (Sweden)

Helen B. Boholano

2017-06-01

Full Text Available Education in the 21st century highlights globalization and internationalization. Preservice teachers in the 21st century are technology savvy. To effectively engage and teach generation Z students, preservice teachers will help the educational system meet this requirement. The educational systems must be outfitted with a prerequisite of ICT resources both hardware and software, and curricula must be designed to promote a collaborative learner-centered environment to which students will relate and respond. This study determines the 21st century skills possessed by the pre-service teachers in terms of social networking. Pre-service teachers use computers in very advanced ways, but educators must remember that they still need guidance to use technology safely and effectively. Through social media the pre-service teachers can use a multitude of applications, including Web 2.0, for their projects. Smart social networking requires critical-thinking skills and the ability to integrate and evaluate real-world scenarios and authentic learning skills for validation.

78 FR 13379 - Wrangell-St. Elias National Park and Preserve, Alaska; Proposed Mining Plan of Operations

Science.gov (United States)

2013-02-27

...] Wrangell-St. Elias National Park and Preserve, Alaska; Proposed Mining Plan of Operations AGENCY: National...) unpatented placer claims within Wrangell-St. Elias National Park and Preserve. Public Availability: This plan...: Wrangell-St. Elias National Park and Preserve Headquarters, Mile 106.8 Richardson Highway, Post Office Box...

77 FR 38488 - Safety Zone; Alexandria Bay Chamber of Commerce, St. Lawrence River, Alexandria Bay, NY

Science.gov (United States)

2012-06-28

... 1625-AA00 Safety Zone; Alexandria Bay Chamber of Commerce, St. Lawrence River, Alexandria Bay, NY... restrict vessels from a portion of the St. Lawrence River during the Alexandria Bay Chamber of Commerce... of proposed rulemaking (NPRM) entitled Safety Zone; Alexandria Bay Chamber of Commerce, St. Lawrence...

Presence of selected chemicals of emerging concern in water and bottom sediment from the St. Louis River, St. Louis Bay, and Superior Bay, Minnesota and Wisconsin, 2010

Science.gov (United States)

Christensen, Victoria G.; Lee, Kathy E.; Kieta, Kristen A.; Elliott, Sarah M.

2012-01-01

The St. Louis Bay of Lake Superior receives substantial urban runoff, wastewater treatment plant effluent, and industrial effluent. In 1987, the International Joint Commission designated the St. Louis Bay portion of the lower St. Louis River as one of the Great Lakes Areas of Concern. Concerns exist about the potential effects of chemicals of emerging concern on aquatic biota because many of these chemicals, including endocrine active chemicals, have been shown to affect the endocrine systems of fish. To determine the occurrence of chemicals of emerging concern in the St. Louis River, the St. Louis Bay, and Superior Bay, the U.S. Geological Survey in cooperation with the Minnesota Pollution Control Agency and the Wisconsin Department of Natural Resources collected water and bottom-sediment samples from 40 sites from August through October 2010. The objectives of this study were to (1) identify the extent to which chemicals of emerging concern, including pharmaceuticals, hormones, and other organic chemicals, occur in the St. Louis River, St. Louis Bay, and Superior Bay, and (2) identify the extent to which the chemicals may have accumulated in bottom sediment of the study area. Samples were analyzed for selected wastewater indicators, hormones, sterols, bisphenol A, and human-health pharmaceuticals. During this study, 33 of 89 chemicals of emerging concern were detected among all water samples collected and 56 of 104 chemicals of emerging concern were detected in bottom-sediment samples. The chemical N,N-diethyl-meta-toluamide (DEET) was the most commonly detected chemical in water samples and 2,6-dimethylnaphthalene was the most commonly detected chemical in bottom-sediment samples. In general, chemicals of emerging concern were detected at a higher frequency in bottom-sediment samples than in water samples. Estrone (a steroid hormone) and hexahydrohexamethyl cyclopentabensopyran (a synthetic fragrance) were the most commonly detected endocrine active chemicals in

Sustainable Nuclear Energy for the 21st Century

International Nuclear Information System (INIS)

2010-09-01

Concerns over energy resource availability, energy security and climate change suggest an important role for nuclear power in supplying sustainable energy in the 21st century. The International Project on Innovative Nuclear Reactors and Fuel Cycles (INPRO) was initiated in 2000 by a resolution of the IAEA General Conference to help ensure that nuclear energy is available to contribute to meeting global energy needs of the 21st century in a sustainable manner. It is a mechanism for IAEA Member States that have joined the project as INPRO members to collaborate on topics of joint interest. By 2010, INPRO membership had grown to 30 countries and the European Commission. The results of INPRO's activities, however, are made available to all IAEA Member States

Towards a 21st century ready curriculum

NARCIS (Netherlands)

Vloon, N.G.J.; Hammer, M.H.M.; Brahimi, N.

2015-01-01

Entrepreneurship and entrepreneurship education is generally viewed upon as being important for economic growth in the 21st century. Teaching entrepreneurship however seems to need another approach than regular education to fulfill the professional and ever changing needs. In this perspective active

Morphing into a 21st Century Trainer.

Science.gov (United States)

Mager, R. F.

1996-01-01

Forces that will affect trainers into the next century include rapid change, information overload, globalization, downsizing, empowerment, and remote worksites. Key characteristics of a 21st-century trainer include performance orientation, technical skills, social skills, self-employability, bilingualism, and international competence. (JOW)

Expression of Functional Human Sialyltransferases ST3Gal1 and ST6Gal1 in Escherichia coli.

Directory of Open Access Journals (Sweden)

Maria Elena Ortiz-Soto

Full Text Available Sialyltransferases (STs are disulfide-containing, type II transmembrane glycoproteins that catalyze the transfer of sialic acid to proteins and lipids and participate in the synthesis of the core structure oligosaccharides of human milk. Sialic acids are found at the outermost position of glycostructures, playing a key role in health and disease. Sialylation is also essential for the production of recombinant therapeutic proteins (RTPs. Despite their importance, availability of sialyltransferases is limited due to the low levels of stable, soluble and active protein produced in bacterial expression systems, which hampers biochemical and structural studies on these enzymes and restricts biotechnological applications. We report the successful expression of active human sialyltransferases ST3Gal1 and ST6Gal1 in commercial Escherichia coli strains designed for production of disulfide-containing proteins. Fusion of hST3Gal1 with different solubility enhancers and substitution of exposed hydrophobic amino acids by negatively charged residues (supercharging-like approach were performed to promote solubility and folding. Co-expression of sialyltransferases with the chaperon/foldases sulfhydryl oxidase, protein disulfide isomerase and disulfide isomerase C was explored to improve the formation of native disulfide bonds. Active sialyltransferases fused with maltose binding protein (MBP were obtained in sufficient amounts for biochemical and structural studies when expressed under oxidative conditions and co-expression of folding factors increased the yields of active and properly folded sialyltransferases by 20%. Mutation of exposed hydrophobic amino acids increased recovery of active enzyme by 2.5-fold, yielding about 7 mg of purified protein per liter culture. Functionality of recombinant enzymes was evaluated in the synthesis of sialosides from the β-d-galactoside substrates lactose, N-acetyllactosamine and benzyl 2-acetamido-2-deoxy-3-O-(β-d-galactopyranosyl-α-d-galactopyranoside.

21st Century Security Manager

OpenAIRE

Stelian ARION

2010-01-01

We live in world of uncertainty that generates major paradigms changing that affect security risk management. Modern organization’s security risks management can’t be done without a profound knowlegde and daily practice for security governance, security risk management and resilience. 21st Century security manager need to deal with several areas of konwledge in order to succesfully manage security risks. The document presents the advantages, disadvantages and challenges for security managers ...

Middle Schools Preparing Young People for 21st Century Life and Work

Science.gov (United States)

Kay, Ken

2009-01-01

In this article, the author describes how middle schools can prepare young people for the challenges and opportunities of the 21st century. Integrating 21st century skills deliberately and systematically into middle school education will empower educators to accomplish many of the elusive goals they have tried to reach for years. Twenty-first…

Long-Lived Digital Data Collections Enabling Research and Education in the 21st Century

Science.gov (United States)

2005-09-01

Collections: Enabling Research and Education in the 21st Century40 LoNG-LiVED DiGiTAL DATA CoLLECTioNS AND LARGE FACiLiTiES Workshop participants drew...Long-Lived Digital Data Collections: Enabling Research and Education in the 21st Century NSB-05-40 Report Documentation Page Form...COVERED - 4. TITLE AND SUBTITLE Long-Lived Digital Data Collections Enabling Research and Education in the 21st Century 5a. CONTRACT NUMBER 5b

St. George Feast: Relation to Eastern Legends and Cults [In Bulgarian

Directory of Open Access Journals (Sweden)

S. Rulinski

2016-07-01

Full Text Available The article examines George as a counterpart to the Sumerian god Ninurta. Feast St. George boasts Georgy feat - creation of the world. The date of the feast – 6th of May, is commented in its relation to the astronomical arguments and Sumerian ancient texts. The main rituals of the feast are described. The most typical folk songs devoted to St. Georgy are listed in the paper appendix.

Myocarditis with ST elevation and elevated cardiac enzymes misdiagnosed as an ST-elevation myocardial infarction.

Science.gov (United States)

Sheldon, Seth H; Crandall, Mark A; Jaffe, Allan S

2012-12-01

Acute myocarditis can mimic ST-elevation myocardial infarction (STEMI). Quickly determining the correct diagnosis is critical given the "time is muscle" implication with a STEMI and the potential adverse effects associated with use of fibrinolytic therapy. A 46-year-old man presented to a rural emergency department with chest pain, and an electrocardiogram (ECG) read as showing 0.1 mV of ST-segment elevation in leads III and aVF. His initial cardiac troponin T was 0.44 ng/mL. He received fibrinolytic therapy for presumed STEMI. Cardiac magnetic resonance imaging was later performed and showed epicardial delayed enhancement consistent with myocarditis. Upon further questioning, he acknowledged 3 days of stuttering chest discomfort and a recent upper respiratory infection, as well as similar chest pain in his wife. A systematic evaluation is essential for acute chest pain, including a focused history, identification of cardiac risk factors, and ECG interpretation. A history of recent viral illness, absence of cardiac risk factors, or ECG findings inconsistent with a single anatomic lesion would suggest a potential alternate diagnosis to STEMI. This case emphasizes the importance of a focused history in the initial evaluation of chest pain. Copyright © 2012 Elsevier Inc. All rights reserved.

78 FR 72056 - Proposed Amendment of Class D and Class E Airspace; Christiansted, St. Croix, VI

Science.gov (United States)

2013-12-02

... Class D and Class E Airspace; Christiansted, St. Croix, VI AGENCY: Federal Aviation Administration (FAA... Class E Airspace at Christiansted, St. Croix, VI, to adjust the geographic coordinates of Henry E..., Christiansted, St. Croix, VI, to bring it in concert with the FAAs aeronautical database. The coordinates would...

ST Product Characteristics and Relationships with Perceptions and Behaviors among Rural Adolescent Males: A Qualitative Study

Science.gov (United States)

Couch, Elizabeth T.; Darius, Ellen F.; Walsh, Margaret M.; Chaffee, Benjamin W.

2017-01-01

Although smoking declines in the United States, the prevalence of male adolescent smokeless tobacco (ST; moist snuff and chewing tobacco) use remains unchanged. ST product characteristics, such as flavoring, packaging, and branding, could influence adolescents' ST initiation and continued use. This qualitative study examines the potential role of…

"Four Ways of Writing the City" : St. Petersburg-Leningrad as a Metaphor in the Poetry of Joseph Brodsky

OpenAIRE

Könönen, Maija

2003-01-01

The present study discusses the theme of St. Petersburg-Leningrad in Joseph Brodsky's verse works. The chosen approach to the evolving im-age of the city in Brodsky's poetry is through four metaphors: St. Petersburg as "the common place" of the Petersburg Text, St. Petersburg as "Paradise and/or Hell", St. Petersburg as "a Utopian City" and St. Petersburg as "a Void". This examination of the city-image focusses on the aspects of space and time as basic categories underlying the poet's po...

Early Stent Thrombosis and Mortality After Primary Percutaneous Coronary Intervention in ST-Segment-Elevation Myocardial Infarction

DEFF Research Database (Denmark)

Dangas, George D; Schoos, Mikkel M.; Steg, Philippe Gabriel

2016-01-01

BACKGROUND: Early stent thrombosis (ST) within 30 days after primary percutaneous coronary intervention in ST-segment-elevation myocardial infarction is a serious event. We sought to determine the predictors of and risk of mortality after early ST according to procedural antithrombotic therapy...... with bivalirudin compared with heparin±GPI because of increased ST within 4 hours after primary percutaneous coronary intervention. However, the mortality attributable to early ST was significantly lower after bivalirudin than after heparin±GPI. CLINICAL TRIAL REGISTRATION: URL: http....... METHODS AND RESULTS: In a patient-level pooled analysis from the Harmonizing Outcomes With Revascularization and Stents in Acute Myocardial Infarction (HORIZONS-AMI) and European Ambulance Acute Coronary Syndrome Angiography (EUROMAX) trials, we examined 30-day outcomes in 4935 patients undergoing primary...

From Imitation to Innovation: A Strategic Adjustment in China's S&T Development

Institute of Scientific and Technical Information of China (English)

Fang Xin

2005-01-01

@@ Since the latter half of 2004, China's top leaders have given higher priority to the issue of national capacity building for S&T innovation. Chinese President Hu Jintao reiterates that stress should be placed on the upgrading of innovation capacity when making overall plans for S&T development,and the task should remain the key link in promoting economic structural readjustment and raising national competitiveness. This strategic transition from imitation to innovation is also found in the National Long- &Medium-term Plan for S&T Development,which is being formulated under the leadership of Premier Wen Jiabao. The author explains the reason behind such a transition and the major administrative measures to be adopted for its implementation.