Two-dimensional intraventricular flow mapping by digital processing conventional color-Doppler echocardiography images.

Science.gov (United States)

Garcia, Damien; Del Alamo, Juan C; Tanne, David; Yotti, Raquel; Cortina, Cristina; Bertrand, Eric; Antoranz, José Carlos; Perez-David, Esther; Rieu, Régis; Fernandez-Aviles, Francisco; Bermejo, Javier

2010-10-01

Doppler echocardiography remains the most extended clinical modality for the evaluation of left ventricular (LV) function. Current Doppler ultrasound methods, however, are limited to the representation of a single flow velocity component. We thus developed a novel technique to construct 2D time-resolved (2D+t) LV velocity fields from conventional transthoracic clinical acquisitions. Combining color-Doppler velocities with LV wall positions, the cross-beam blood velocities were calculated using the continuity equation under a planar flow assumption. To validate the algorithm, 2D Doppler flow mapping and laser particle image velocimetry (PIV) measurements were carried out in an atrio-ventricular duplicator. Phase-contrast magnetic resonance (MR) acquisitions were used to measure in vivo the error due to the 2D flow assumption and to potential scan-plane misalignment. Finally, the applicability of the Doppler technique was tested in the clinical setting. In vitro experiments demonstrated that the new method yields an accurate quantitative description of the main vortex that forms during the cardiac cycle (mean error for vortex radius, position and circulation). MR image analysis evidenced that the error due to the planar flow assumption is close to 15% and does not preclude the characterization of major vortex properties neither in the normal nor in the dilated LV. These results are yet to be confirmed by a head-to-head clinical validation study. Clinical Doppler studies showed that the method is readily applicable and that a single large anterograde vortex develops in the healthy ventricle while supplementary retrograde swirling structures may appear in the diseased heart. The proposed echocardiographic method based on the continuity equation is fast, clinically-compliant and does not require complex training. This technique will potentially enable investigators to study of additional quantitative aspects of intraventricular flow dynamics in the clinical setting by

Doppler tomography in fusion plasmas and astrophysics

DEFF Research Database (Denmark)

Salewski, Mirko; Geiger, B.; Heidbrink, W. W.

2015-01-01

Doppler tomography is a well-known method in astrophysics to image the accretion flow, often in the shape of thin discs, in compact binary stars. As accretion discs rotate, all emitted line radiation is Doppler-shifted. In fast-ion Dα (FIDA) spectroscopy measurements in magnetically confined plasma......, the Dα-photons are likewise Doppler-shifted ultimately due to gyration of the fast ions. In either case, spectra of Doppler-shifted line emission are sensitive to the velocity distribution of the emitters. Astrophysical Doppler tomography has lead to images of accretion discs of binaries revealing bright...... and limits, analogies and differences in astrophysical and fusion plasma Doppler tomography and what can be learned by comparison of these applications....

Power Doppler ultrasonography for assessment of synovitis in the metacarpophalangeal joints of patients with rheumatoid arthritis: a comparison with dynamic magnetic resonance imaging

DEFF Research Database (Denmark)

Szkudlarek, Marcin; Court-Payen, M; Strandberg, C

2001-01-01

OBJECTIVE: To evaluate the effectiveness of power Doppler ultrasonography (PDUS) for assessing inflammatory activity in the metacarpophalangeal (MCP) joints of patients with rheumatoid arthritis (RA), using dynamic magnetic resonance imaging (MRI) as a reference method. METHODS: PDUS and dynamic...... MRI were performed on 54 MCP joints of 15 patients with active RA and on 12 MCP joints of 3 healthy controls. PDUS was performed with a LOGIQ 500 unit by means of a 7-13-MHz linear array transducer. Later the same day, MRI was performed with a 1.0T MR unit. A series of 24 coronal T1-weighted images...

Wide Angle Michelson Doppler Imaging Interferometer (WAMDII)

Science.gov (United States)

Roberts, B.

1986-01-01

The wide angle Michelson Doppler imaging interferometer (WAMDII) is a specialized type of optical Michelson interferometer working at sufficiently long path difference to measure Doppler shifts and to infer Doppler line widths of naturally occurring upper atmospheric Gaussian line emissions. The instrument is intended to measure vertical profiles of atmospheric winds and temperatures within the altitude range of 85 km to 300 km. The WAMDII consists of a Michelson interferometer followed by a camera lens and an 85 x 106 charge coupled device photodiode array. Narrow band filters in a filter wheel are used to isolate individual line emissions and the lens forms an image of the emitting region on the charge coupled device array.

Doppler-Zeeman mapping of the magnetic CP star HD 215441

Science.gov (United States)

Khokhlova, V. L.; Vasilchenko, D. V.; Stepanov, V. V.; Tsymbal, V. V.

1997-07-01

The method of Vasilchenko et al. (1996) is used to obtain a Doppler-Zeeman map of the magnetic CP star HD 215441. The magnetic field is approximated by a magnetic dipole that is arbitrarily shifted from the star center. The solution of the inverse problem yields the dipole parameters and the maps of Si, Ti, Cr, and Fe abundance anomalies; the coordinates of local magnetic vectors on the star surface are computed. A comparison of the distribution of abundance anomalies and the magnetic-field configuration reveals that in the region where the magnetic-field lines are vertical (near the magnetic pole), Si, Ti and Cr are highly deficient, while the Fe enhancement is strongest. In the regions where the magnetic-field lines are horizontal (near the magnetic equator), Si, Ti and Cr show the greatest overabundance. In these regions, the Fe abundance is also slightly enhanced and exhibits, as it were, a secondary maximum. The factors that limit the accuracy of Doppler-Zeeman mapping are reviewed.

ISAR imaging using the instantaneous range instantaneous Doppler method

CSIR Research Space (South Africa)

Wazna, TM

2015-10-01

Full Text Available In Inverse Synthetic Aperture Radar (ISAR) imaging, the Range Instantaneous Doppler (RID) method is used to compensate for the nonuniform rotational motion of the target that degrades the Doppler resolution of the ISAR image. The Instantaneous Range...

21 CFR 892.1550 - Ultrasonic pulsed doppler imaging system.

Science.gov (United States)

2010-04-01

... system. (a) Identification. An ultrasonic pulsed doppler imaging system is a device that combines the... 21 Food and Drugs 8 2010-04-01 2010-04-01 false Ultrasonic pulsed doppler imaging system. 892.1550... include signal analysis and display equipment, patient and equipment supports, component parts, and...

Neurilemmoma of the glans penis: ultrasonography and magnetic resonance imaging findings.

Science.gov (United States)

Jung, Dae Chul; Hwang, Sung Il; Jung, Sung Il; Kim, Sun Ho; Kim, Seung Hyup

2006-01-01

Neurilemmoma of the glans penis is rare, and no imaging findings have been reported. A case of neurilemmoma of the glans penis is presented. Ultrasonography (US) and magnetic resonance imaging revealed a well-defined small mass in the glans penis. The mass appeared hypoechoic on gray-scale US and hypervascular on color Doppler US. Magnetic resonance imaging revealed high signal intensity of the mass on a T2-weighted image and strong enhancement on a contrast-enhanced T1-weighted image.

Clinical outcome and imaging changes after intraarticular (IA) application of etanercept or methylprednisolone in rheumatoid arthritis: Magnetic resonance imaging and ultrasound-Doppler show no effect of IA injections in the wrist after 4 weeks

DEFF Research Database (Denmark)

Boesen, M.; Boesen, L.; Jensen, K.E.

2008-01-01

Objective. To assess the magnetic resonance imaging (MRI) and ultrasound (US) changes in the wrist of patients with rheumatoid arthritis (RA) 4 weeks after an US guided intraarticular (IA) injection. Methods. Contrast enhanced MRI and US-Doppler were performed at baseline and 4 weeks after IA....... Conclusion. In contrast to the clinical evaluation, imaging measures of relevance for the estimation of inflammation, US-Doppler, US RI, MRI synovitis, and bone-marrow edema did not change 4 weeks after a single IA injection of either methylprednisolone or etanercept in the wrist. Within the same period...... target joint score (p 4 weeks. Baseline MRI synovitis score was mean 5.08 (range 3-9) and was unchanged at followup in the whole group (p = 0.52) and between treatment groups (p = 0.43). MRI edema score (mean 4.46, range 0...

A Comparison Study of Vector Velocity, Spectral Doppler and Magnetic Resonance of Blood Flow in the Common Carotid Artery

DEFF Research Database (Denmark)

Brandt, Andreas Hjelm; Hansen, Kristoffer Lindskov; Ewertsen, Caroline

2018-01-01

Magnetic resonance phase contrast angiography (MRA) is the gold standard for blood flow evaluation. Spectral Doppler ultrasound (SDU) is the first clinical choice, although the method is angle dependent. Vector flow imaging (VFI) is an angle-independent ultrasound method. The aim of the study...

Longitudinal microvascularity in achilles tendinopathy (power doppler ultrasound, magnetic resonance imaging time-intensity curves and the Victorian Institute of Sport Assessment-Achilles questionnaire): a pilot study

International Nuclear Information System (INIS)

Richards, Paula J.; McCall, Iain W.; Day, Christopher; Belcher, John; Maffulli, Nicola

2010-01-01

To evaluate the imaging of the natural history of Achilles tendinopathy microvascularisation in comparison with symptoms, using a validated disease-specific questionnaire [the Victorian Institute of Sport Assessment-Achilles (VISA-A)]. A longitudinal prospective pilot study of nine patients with post-contrast magnetic resonance imaging (MRI), time-intensity curve (TIC) enhancement, ultrasound (US) and power Doppler (PD) evaluation of tendinopathy of the mid-Achilles tendon undergoing conservative management (eccentric exercise) over 1 year. There were five men and four women [mean age 47 (range 30-62) years]. Six asymptomatic tendons with normal US and MRI appearance showed less enhancement than the tibial metaphysis did and showed a flat, constant, but very low rate of enhancement in the bone and Achilles tendon (9-73 arbitrary TIC units). These normal Achilles tendons on imaging showed a constant size throughout the year (mean 4.9 mm). At baseline the TIC enhancement in those with tendinopathy ranged from 90 arbitrary units to 509 arbitrary units. Over time, 11 abnormal Achilles tendons, whose symptoms settled, were associated with a reduction in MRI enhancement mirrored by a reduction in the number of vessels on power Doppler (8.0 to 2.7), with an improvement in morphology and a reduction in tendon size (mean 15-10.6 mm). One tendon did not change its abnormal imaging features, despite improving symptoms. Two patients developed contralateral symptoms and tendinopathy, and one had more abnormal vascularity on power Doppler and higher MRI TIC peaks in the asymptomatic side. In patient with conservatively managed tendinopathy of the mid-Achilles tendon over 1 year there was a reduction of MRI enhancement and number of vessels on power Doppler, followed by morphological improvements and a reduction in size. Vessels per se related to the abnormal morphology and size of the tendon rather than symptoms. Symptoms improve before the Achilles size reduces and the

Thyroid perfusion imaging as a diagnostic tool in Graves' disease. Arterial spin labeling magnetic resonance imaging vs. colour-coded Doppler ultrasound

Energy Technology Data Exchange (ETDEWEB)

Muessig, K. [University Hospital of Duesseldorf (Germany). Dept. of Metabolic Diseases; Leibniz Center for Diabetes Research, Duesseldorf (Germany). Inst. for Clinical Diabetology; University Hospital of Tuebingen (Germany). Div. of Endocrinology, Diabetes, Nephrology, Angiology, and Clinical Chemistry; Schraml, C.; Schwenzer, N.F. [University Hospital of Tuebingen (Germany). Dept. of Radiology, Section on Experimental Radiology; University Hospital of Tuebingen (Germany). Dept. of Radiology, Diagnostic and Interventional Radiology; Rietig, R.; Balletshofer, B. [University Hospital of Tuebingen (Germany). Div. of Endocrinology, Diabetes, Nephrology, Angiology, and Clinical Chemistry; Martirosian, P.; Haering, H.U.; Schick, F. [University Hospital of Tuebingen (Germany). Dept. of Radiology, Section on Experimental Radiology; Claussen, C.D. [University Hospital of Tuebingen (Germany). Dept. of Radiology, Diagnostic and Interventional Radiology

2012-12-15

Purpose: Though increased thyroid perfusion assessed by colour-coded Doppler ultrasound (CDUS) is characteristic of Graves' disease (GD), sometimes perfusion assessment by CDUS is not possible. In these cases, arterial spin labelling (ASL), a novel magnetic resonance imaging (MRI) technique allowing non-invasive thyroid perfusion quantification, may have additional diagnostic value. We aimed to evaluate the potential of ASL-MRI for assessment of increased blood perfusion in patients with GD compared to CDUS. Materials and Methods: Thyroid perfusion was measured by CDUS (volume flow rate calculated from pulsed wave Doppler signals and vessel diameter) and ASL-MRI at 1.5 T in 7 patients with GD and 10 healthy controls. Results: In patients with GD, average perfusion in both thyroid lobes was markedly increased compared to controls. Both techniques applied for volume related perfusion as well as absolute volume flow in thyroid feeding vessels provided similar results (all p = 0.0008). Using a cut-off value of 22 ml/min for the volume flow rate assessed by CDUS in the four feeding vessels allowed discrimination between patients with GD and controls in all cases. After adjusting thyroid perfusion for the differences in organ volume, both CDUS and ASL revealed also complete discrimination between health and disease. Conclusion: Thyroid perfusion measurement by ASL-MRI reliably discriminate GD from normal thyroid glands. In patients in whom thyroid arteries cannot be depicted by CDUS for technical or anatomical reasons, ASL-MRI may have additional diagnostic value. (orig.)

Evaluation of aortic regurgitation using cine magnetic resonance imaging

International Nuclear Information System (INIS)

Tamai, Takuya; Konishi, Tokuji; Okamoto, Shinya; Sakuma, Hajime; Takeda, Kan; Nakano, Takeshi

1993-01-01

Cine magnetic resonance imaging (MRI) was used to assess aortic regurgitation (AR) in 13 patients with valvular disease and 3 normal subjects, and the results were compared to color Doppler flow mapping findings. AR produced a signal void in the left ventricle during the diastolic phase in all patients by MRI. There were no false positive or negative results compared with echocardiographic findings. Visual grading of cine MRI gave results similar to color flow Doppler echocardiography (88%). The distance and the area of aortic regurgitation using MRI correlated well with color Doppler flow mapping (r=0.82 and 0.88). However, measurements of distance and area by color flow Doppler tended to be larger than those by cine MRI. With current techniques echocardiography may overestimate the severity of AR as compared with cine MRI. In addition, MRI gives clinically useful information in patients in whom transthoracic Doppler echocardiography is not adequate. (author)

Evaluation of mitral regurgitation by cine magnetic resonance imaging

International Nuclear Information System (INIS)

Kobayashi, Shiro; Kishi, Naohiro; Kumai, Toshihiko

1993-01-01

Valvular regurgitation can be detected as a region of signal loss ('flow void') by cardiac cine magnetic resonance (MR) imaging. Cine MR images of 36 patients with mitral regurgitation caused by mitral valve prolapse (MVP) and non-MVP were evaluated and compared with color Doppler flow images. The direction, distance, area and timing of flow void were detected in all patients in several different planes at mitral level with a 0.5 Tesla superconducting magnet by an ECG-gated fast field echo technique. In 23 of the 36 patients contiguous multiple transaxial images were also obtained to calculate the volumes of flow void and the left atrium. The direction of flow void tended to deviate to the opposite side within the left atrium in MVP. The frame showing maximal area of flow void was demonstrated in mid-systole in 24 of the 36 patients (67%). The distance, area and volume of flow void were concordant with the grade from color Doppler flow images. The volumes of flow void and the left atrium correlated (n=19, r=0.74, p<0.05) in MVP. In conclusion, cine MR images in several different planes or contiguous multiple slices are useful in determining spatial orientation and the extent and timing of mitral regurgitation noninvasively. Furthermore, calculation of the volume of flow void enables the assessment of the semiquantitation of mitral regurgitation. (author)

Automated flow quantification in valvular heart disease based on backscattered Doppler power analysis: implementation on matrix-array ultrasound imaging systems.

Science.gov (United States)

Buck, Thomas; Hwang, Shawn M; Plicht, Björn; Mucci, Ronald A; Hunold, Peter; Erbel, Raimund; Levine, Robert A

2008-06-01

Cardiac ultrasound imaging systems are limited in the noninvasive quantification of valvular regurgitation due to indirect measurements and inaccurate hemodynamic assumptions. We recently demonstrated that the principle of integration of backscattered acoustic Doppler power times velocity can be used for flow quantification in valvular regurgitation directly at the vena contracta of a regurgitant flow jet. We now aimed to accomplish implementation of automated Doppler power flow analysis software on a standard cardiac ultrasound system utilizing novel matrix-array transducer technology with detailed description of system requirements, components and software contributing to the system. This system based on a 3.5 MHz, matrix-array cardiac ultrasound scanner (Sonos 5500, Philips Medical Systems) was validated by means of comprehensive experimental signal generator trials, in vitro flow phantom trials and in vivo testing in 48 patients with mitral regurgitation of different severity and etiology using magnetic resonance imaging (MRI) for reference. All measurements displayed good correlation to the reference values, indicating successful implementation of automated Doppler power flow analysis on a matrix-array ultrasound imaging system. Systematic underestimation of effective regurgitant orifice areas >0.65 cm(2) and volumes >40 ml was found due to currently limited Doppler beam width that could be readily overcome by the use of new generation 2D matrix-array technology. Automated flow quantification in valvular heart disease based on backscattered Doppler power can be fully implemented on board a routinely used matrix-array ultrasound imaging systems. Such automated Doppler power flow analysis of valvular regurgitant flow directly, noninvasively, and user independent overcomes the practical limitations of current techniques.

Endosonographic and color doppler flow imaging alterations observed within irradiated rectal cancer

International Nuclear Information System (INIS)

Alexander, Archie A.; Palazzo, Juan P.; Ahmad, Neelofur R.; Liu, J.-B.; Forsberg, Flemming; Marks, John

1996-01-01

Purpose: To correlate the endosonographic and color Doppler flow imaging alterations observed in irradiated rectal cancers with the pathologic features of radiation response, and to evaluate the potential impact of altered blood flow on the integrity of the surgical anastamosis. Methods and Materials: Endosonography with color and pulsed wave Doppler was performed on 20 rectal cancer masses before and after high dose preoperative radiation (XRT). Pre- and post-XRT observations included comparing alterations in tumor size, sonographic echotexture, color Doppler flow, and pulsatility indices. Comparisons were made with pathologic findings in the irradiated specimens and with the incidence of anastomotic failure. Results: Compared to pre-XRT observations, irradiated rectal cancers decreased in size and became either mixed in echogenicity with less apparent color Doppler flow (16 of 20) or unchanged in color Doppler flow and echotexture (4 of 20). Those with less flow (16 of 20) were imaged later (mean = 90.2 ± 12.1 days) than those without change in color Doppler flow (mean = 21.7 ± 2.7 days). Pathologically, the group of four without change in color Doppler signal had features of acute inflammation which were not observed in 16 of 20 imaged later. Based on pulsatility index measurements, both high and low resistance vessels were detected and confirmed by immunohistochemical staining, and features of postradiation obliterative vasculitis were observed. Only one primary anastomosis in 14 patients with decreased flow failed. Conclusions: The sonographic and color Doppler flow imaging alterations observed within irradiated rectal cancer correlated with changes of postradiation obliterative vasculitis. The apparent diminished local blood flow within high and low resistance vessels post-XRT did not result in an increased incidence of anastomotic failures

Phylloedes tumor of breast: findings at mammography, sonography and color Doppler imaging

International Nuclear Information System (INIS)

Park, Kun Choon; Ahn, Sei Hyun; Kim, Young Hwan; Choi, Hye Yong; Baek, Seung Yon; Yoon, Jeong Hyun

1994-01-01

The phylloides tumor of the breast is rare. the purposes of this study were to find the characteristic findings at mammography, sonography, and color Doppler imaging and to evaluate the usefulness of color Doppler study as an additional modality in the diagnosis of phylloides tumor and differentiation between benign and malignant varieties. Eight cases, who were pathologically proven as pylloides tumors, were retrospectively studied. The findings at histologic examination suggested benign in five, malignantin two, and borderline in one. We analyzed the mammograms of all eight patients and sonogram and color Doppler images of four patients. Phylloides tumors were seen as dense masses with lobulated margins in mammograms. On sonography, they showed relatively well-defined masses with in homogenous internal echo pattern and central echogenic areas. They were characterized by the presence of arterial and venous flows in the center and periphery of the lesion on color Doppler imaging and spectral analysis. We conclude that mammographic, sonographic and even color Doppler findings are not predictive of benign or malignant nature of the phylloides tumor. However, mammography and sonography with color Doppler interrogation are helpful in the diagnosis of phylloides tumor

The Assessment of Left Ventricular Time-Varying Radius Using Tissue Doppler Imaging

Directory of Open Access Journals (Sweden)

Fardin Mirbolouk

2012-03-01

Full Text Available Background: Left ventricular twist/torsion is believed to be a sensitive indicator of systolic and diastolic performance. To obtain circumferential rotation using tissue Doppler imaging, we need to estimate the time-varying radius of the left ventricle throughout the cardiac cycle to convert the tangential velocity into angular velocity. Objectives: The aim of this study was to investigate accuracy of measured LV radius using tissue Doppler imaging throughout the cardiac cycle compared to two-dimensional (2D imaging. Methods: A total of 35 subjects (47±12 years old underwent transthoracic echocardiographic standard examinations. Left ventricular radius during complete cardiac cycle measured using tissue Doppler and 2D-imaging at basal and apical short axis levels. For this reason, the 2D-images and velocity-time data derived and transferred to a personal computer for off-line analysis. 2D image frames analyzed via a program written in the MATLAB software. Velocity-time data from anteroseptal at basal level (or anterior wall at apical level and posterior walls transferred to a spreadsheet Excel program for the radius calculations. Linear correlation and Bland-Altman analysis were calculated to assess the relationships and agreements between the tissue Doppler and 2D-measured radii throughout the cardiac cycle. Results: There was significant correlation between tissue Doppler and 2D-measured radii and the Pearson correlation coefficients were 0.84 to 0.97 (P<0.05. Bland-Altman analysis by constructing the 95% limits of agreement showed that the good agreements existed between the two methods. Conclusion: It can be concluded from our experience that the tissue Doppler imaging can reasonably estimate radius of the left ventricle throughout the cardiac cycle.

Doppler ultrasound and magnetic resonance for evaluation of patients treated surgically for aortic coarctation

International Nuclear Information System (INIS)

Canteli, B.; Saez, F.; Garcia, F.; Cabrera, A.; Galdeano, J.M.; Rodriguez, O.

1994-01-01

Doppler ultrasound and magnetic resonance were performed in a series of 39 patients who had been treated surgically for aortic coarctation. The purpose was to assess the different Doppler gradients, comparing the findings with morphological data disclosed by magnetic resonance. The aortic caliber in the operative field was pathological in 7 patients (ratio between the caliber at the level of the lesion and that of descending aorta of less than 0.7). When the patients were considered as a group. Doppler ultrasound did not show satisfactory sensitivity (29%-43%), specificity (74%) or positive predictive value (17%-23%). Only the negative predictive value (85%-88%) presented more favorable results. When the Subgroup of patients without associated cardiac abnormalities or collateral circulation was studied alone, the following results were found: sensitivity, 100%; specificity, 81%-90%, positive predictive value, 33%-50%, negative predictive value, 100%, similar to those reported in the literature. Thus, we consider that Doppler ultrasound is a harmless and low cost diagnostic method that is highly suitable for follow-up of these patients, within certain limits. Magnetic resonance is the method of choice for the noninvasive assessment of aortic morphology. (Author)

Imaging doppler lidar for wind turbine wake profiling

Science.gov (United States)

Bossert, David J.

2015-11-19

An imaging Doppler lidar (IDL) enables the measurement of the velocity distribution of a large volume, in parallel, and at high spatial resolution in the wake of a wind turbine. Because the IDL is non-scanning, it can be orders of magnitude faster than conventional coherent lidar approaches. Scattering can be obtained from naturally occurring aerosol particles. Furthermore, the wind velocity can be measured directly from Doppler shifts of the laser light, so the measurement can be accomplished at large standoff and at wide fields-of-view.

2D Doppler backscattering using synthetic aperture microwave imaging of MAST edge plasmas

Science.gov (United States)

Thomas, D. A.; Brunner, K. J.; Freethy, S. J.; Huang, B. K.; Shevchenko, V. F.; Vann, R. G. L.

2016-02-01

Doppler backscattering (DBS) is already established as a powerful diagnostic; its extension to 2D enables imaging of turbulence characteristics from an extended region of the cut-off surface. The Synthetic Aperture Microwave Imaging (SAMI) diagnostic has conducted proof-of-principle 2D DBS experiments of MAST edge plasma. SAMI actively probes the plasma edge using a wide (±40° vertical and horizontal) and tuneable (10-34.5 GHz) beam. The Doppler backscattered signal is digitised in vector form using an array of eight Vivaldi PCB antennas. This allows the receiving array to be focused in any direction within the field of view simultaneously to an angular range of 6-24° FWHM at 10-34.5 GHz. This capability is unique to SAMI and is a novel way of conducting DBS experiments. In this paper the feasibility of conducting 2D DBS experiments is explored. Initial observations of phenomena previously measured by conventional DBS experiments are presented; such as momentum injection from neutral beams and an abrupt change in power and turbulence velocity coinciding with the onset of H-mode. In addition, being able to carry out 2D DBS imaging allows a measurement of magnetic pitch angle to be made; preliminary results are presented. Capabilities gained through steering a beam using a phased array and the limitations of this technique are discussed.

Dispersed single-phase-step Michelson interferometer for Doppler imaging using sunlight.

Science.gov (United States)

Wan, Xiaoke; Ge, Jian

2012-09-15

A Michelson interferometer is dispersed with a fiber array-fed spectrograph, providing 59 Doppler sensing channels using sunlight in the 510-570 nm wavelength region. The interferometer operates at a single-phase-step mode, which is particularly advantageous in multiplexing and data processing compared to the phase-stepping mode of other interferometer spectrometer instruments. Spectral templates are prepared using a standard solar spectrum and simulated interferometer modulations, such that the correlation function with a measured 1D spectrum determines the Doppler shift. Doppler imaging of a rotating cylinder is demonstrated. The average Doppler sensitivity is ~12 m/s, with some channels reaching ~5 m/s.

Evaluation of tissue doppler echocardiography and T2* magnetic resonance imaging in iron load of patients with thalassemia major.

Science.gov (United States)

Saravi, Mehrdad; Tamadoni, Ahmad; Jalalian, Rozita; Mahmoodi-Nesheli, Hassan; Hojati, Mosatafa; Ramezani, Saeed

2013-01-01

Iron-mediated cardiomyopathy is the main complication of thalassemia major (TM) patients. Therefore, there is an important clinical need in the early diagnosis and risk stratification of patients. The aim of this study was to evaluate the efficacy of tissue doppler imaging (TDI) to study cardiac iron overload in patients with TM using T2* magnetic resonance (MR) as the gold-standard non-invasive diagnostic test. A total of 100 TM patients with the mean age of 19±7 years and 100 healthy controls 18.8±7 years were evaluated. Conventional echocardiography, TDI, and cardiac MRI T2* were performed in all subjects. TDI measures included myocardial systolic (Sm), early (Em) and late (Am) diastolic velocities at basal and middle segments of septal and lateral LV wall. The TM patients were also subgrouped according to those with iron load (T2* ≤ 20 ms) and those without (T2* > 20 ms), and also severe (T2* ≤ 10 ms) versus the non-severe (T2* ≤ 10 ms). Using T2* cardiovascular MR, abnormal myocardial iron load (T2* ≤ 20 ms) was detected in 84% of the patients and among these, 50% (42/84) had severe (T2* ≤ 10 ms) iron load. The mean T2* was 11.6±8.6 ms (5-36.7). A negative linear correlation existed between transfusion period of patients and T2* levels (r = -0.53, p=0.02). The following TDI measures were lower in patients than in controls: basal septal Am (p<0.05), mid-septal Em and Am (p<0.05), basal lateral Am (p<0.05), mid-lateral LV wall Sm (p<0.05) and Am (p<0.05). Tissue doppler imaging is helpful in predicting the presence of myocardial iron load in Thalassemia patients. Therefore, it can be used for screening of thalassemia major patients.

Diagnostic agreement between panoramic radiographs and color doppler images of carotid atheroma

Directory of Open Access Journals (Sweden)

Claudia Maria Romano-Sousa

2009-02-01

Full Text Available The aim of this study was to investigate the agreement between diagnoses of calcified atheroma seen on panoramic radiographs and color Doppler images. Our interest stems from the fact that panoramic images can show the presence of atheroma regardless of the level of obstruction detected by color Doppler images. Panoramic and color Doppler images of 16 patients obtained from the archives of the Health Department of the city of Valença, RJ, Brazil, were analyzed in this study. Both sides of each patient were observed on the images, with a total of 32 analyzed cervical regions. The level of agreement between diagnoses was analyzed using the Kappa statistics. There was a high level of agreement, with a Kappa value of 0.78. In conclusion, panoramic radiographs can help detecting calcifications in the cervical region of patients susceptible to vascular diseases predisposing to myocardial infarction and cerebrovascular accidents. If properly trained and informed, dentists can refer their patients to a physician for a cardiovascular evaluation in order to receive proper and timely medical treatment.

Design and Ground Calibration of the Helioseismic and Magnetic Imager (HMI) Instrument on the Solar Dynamics Observatory (SDO)

Science.gov (United States)

Schou, J.; Scherrer, P. H.; Bush, R. I.; Wachter, R.; Couvidat, S.; Rabello-Soares, M. C.; Bogart, R. S.; Hoeksema, J. T.; Liu, Y.; Duvall, T. L., Jr.;

Evaluation of renal allograft rejection by Doppler sonography and MR imaging

International Nuclear Information System (INIS)

Steinberg, H.V.; Nelson, R.C.; Murphy, F.B.; Baumgartner, B.R.; Bourke, E.; Delaney, V.B.; Whelchel, J.B.; Bernardino, M.E.

1986-01-01

The authors prospectively studies the efficacy of Doppler sonography and MR imaging in evaluating renal allografts, with specific attention to transplant rejection. Based on study findings, we were unable to make a statement with respect to the appearance or accuracy of diagnosing cyclosporin toxicity or acute tubular necrosis by either modality due to concomitant rejection in the few patients so afflicted. Moreover, the ability to predict and diagnose the presence or absence of allograft rejection was not affected by different serum creatinine values. Most important, however, Doppler sonography was shown to be superior to MR imaging in evaluating for allograft rejection, as evidenced by its higher sensitivity (100% vs. 71%), specificity (88% vs. 75%), and accuracy (96% vs. 73%). Thus, because of its low cost and ease of accessibility, Doppler sonography should become the primary modality for renal transplant screening

Spatially Resolved MR-Compatible Doppler Ultrasound: Proof of Concept for Triggering of Diagnostic Quality Cardiovascular MRI for Function and Flow Quantification at 3T.

Science.gov (United States)

Crowe, Lindsey Alexandra; Manasseh, Gibran; Chmielewski, Aneta; Hachulla, Anne-Lise; Speicher, Daniel; Greiser, Andreas; Muller, Hajo; de Perrot, Thomas; Vallee, Jean-Paul; Salomir, Rares

2018-02-01

We demonstrate the use of a magnetic-resonance (MR)-compatible ultrasound (US) imaging probe using spatially resolved Doppler for diagnostic quality cardiovascular MR imaging (MRI) as an initial step toward hybrid US/MR fetal imaging. A newly developed technology for a dedicated MR-compatible phased array ultrasound-imaging probe acquired pulsed color Doppler carotid images, which were converted in near-real time to a trigger signal for cardiac cine and flow quantification MRI. Ultrasound and MR data acquired simultaneously were interference free. Conventional electrocardiogram (ECG) and the proposed spatially resolved Doppler triggering were compared in 10 healthy volunteers. A synthetic "false-triggered" image was retrospectively processed using metric optimized gating (MOG). Images were scored by expert readers, and sharpness, cardiac function and aortic flow were quantified. Four-dimensional (4-D) flow (two volunteers) showed feasibility of Doppler triggering over a long acquisition time. Imaging modalities were compatible. US probe positioning was stable and comfortable. Image quality scores and quantified sharpness were statistically equal for Doppler- and ECG-triggering (p ). ECG-, Doppler-triggered, and MOG ejection fractions were equivalent (p ), with false-triggered values significantly lower (p 0.05). 4-D flow quantification gave consistent results between ECG and Doppler triggering. We report interference-free pulsed color Doppler ultrasound during MR data acquisition. Cardiovascular MRI of diagnostic quality was successfully obtained with pulsed color Doppler triggering. The hardware platform could further enable advanced free-breathing cardiac imaging. Doppler ultrasound triggering is applicable where ECG is compromised due to pathology or interference at higher magnetic fields, and where direct ECG is impossible, i.e., fetal imaging.

Doppler ultrasound imaging techniques for assessment of synovial inflammation

Directory of Open Access Journals (Sweden)

Filippucci E

2013-09-01

Full Text Available Emilio Filippucci,1 Fausto Salaffi,1 Marina Carotti,2 Walter Grassi1 1Rheumatology Department, Polytechnic University of the Marche, Ancona, Italy; 2Department of Radiology, Polytechnic University of the Marche, Ancona, Italy Abstract: Ultrasound is an evolving technique, and the rapid progress made in ultrasound technology over the past ten years has dramatically increased its range of applications in rheumatology. One of the most exciting advances is the use of Doppler ultrasound imaging in the assessment of blood flow abnormalities at the synovial tissue level in patients with chronic inflammatory arthritis. This review describes the Doppler techniques available and their main applications in patients with inflammatory arthritis, discusses the evidence supporting their use, and outlines the latest advances in hardware and software. Spectral, color, and power Doppler allow sensitive assessment of vascular abnormalities at the synovial tissue level. Use of contrast agents enhances visualization of the small synovial vessels using color or power Doppler ultrasound and allows for accurate characterization of the rheumatoid pannus. Doppler techniques represent a unique method for assessment of synovial inflammation, showing blood flow characteristics in real time. They are safe, noninvasive, cost-effective, and have high sensitivity in revealing and monitoring synovitis. However, several questions still need to be answered. In the near future, the Doppler techniques described here, together with upcoming hardware and software facilities, will be investigated further and a consensus will be reached on their feasibility and appropriate use in daily rheumatologic practice. Keywords: power and color Doppler techniques, ultrasound, contrast media, synovitis, rheumatoid arthritis

Preliminary measurements of the edge magnetic field pitch from 2-D Doppler backscattering in MAST and NSTX-U (invited)

Science.gov (United States)

Vann, R. G. L.; Brunner, K. J.; Ellis, R.; Taylor, G.; Thomas, D. A.

2016-11-01

The Synthetic Aperture Microwave Imaging (SAMI) system is a novel diagnostic consisting of an array of 8 independently phased antennas. At any one time, SAMI operates at one of the 16 frequencies in the range 10-34.5 GHz. The imaging beam is steered in software post-shot to create a picture of the entire emission surface. In SAMI's active probing mode of operation, the plasma edge is illuminated with a monochromatic source and SAMI reconstructs an image of the Doppler back-scattered (DBS) signal. By assuming that density fluctuations are extended along magnetic field lines, and knowing that the strongest back-scattered signals are directed perpendicular to the density fluctuations, SAMI's 2-D DBS imaging capability can be used to measure the pitch of the edge magnetic field. In this paper, we present preliminary pitch angle measurements obtained by SAMI on the Mega Amp Spherical Tokamak (MAST) at Culham Centre for Fusion Energy and on the National Spherical Torus Experiment Upgrade at Princeton Plasma Physics Laboratory. The results demonstrate encouraging agreement between SAMI and other independent measurements.

Laser Doppler perfusion imaging with a complimentary metal oxide semiconductor image sensor

NARCIS (Netherlands)

Serov, Alexander; Steenbergen, Wiendelt; de Mul, F.F.M.

2002-01-01

We utilized a complimentary metal oxide semiconductor video camera for fast f low imaging with the laser Doppler technique. A single sensor is used for both observation of the area of interest and measurements of the interference signal caused by dynamic light scattering from moving particles inside

FIRST ZEEMAN DOPPLER IMAGING OF A COOL STAR USING ALL FOUR STOKES PARAMETERS

International Nuclear Information System (INIS)

Rosén, L.; Kochukhov, O.; Wade, G. A.

2015-01-01

Magnetic fields are ubiquitous in active cool stars, but they are in general complex and weak. Current Zeeman Doppler imaging (ZDI) studies of cool star magnetic fields chiefly employ circular polarization observations because linear polarization is difficult to detect and requires a more sophisticated radiative transfer modeling to interpret. But it has been shown in previous theoretical studies, and in the observational analyses of magnetic Ap stars, that including linear polarization in the magnetic inversion process makes it possible to correctly recover many otherwise lost or misinterpreted magnetic features. We have obtained phase-resolved observations in all four Stokes parameters of the RS CVn star II Peg at two separate epochs. Here we present temperature and magnetic field maps reconstructed for this star using all four Stokes parameters. This is the very first such ZDI study of a cool active star. Our magnetic inversions reveal a highly structured magnetic field topology for both epochs. The strength of some surface features is doubled or even quadrupled when linear polarization is taken into account. The total magnetic energy of the reconstructed field map also becomes about 2.1–3.5 times higher. The overall complexity is also increased as the field energy is shifted toward higher harmonic modes when four Stokes parameters are used. As a consequence, the potential field extrapolation of the four Stokes parameter ZDI results indicates that magnetic field becomes weaker at a distance of several stellar radii due to a decrease of the large-scale field component

The utility of ultrasound superb microvascular imaging for evaluation of breast tumour vascularity: comparison with colour and power Doppler imaging regarding diagnostic performance.

Science.gov (United States)

Park, A Y; Seo, B K; Woo, O H; Jung, K S; Cho, K R; Park, E K; Cha, S H; Cha, J

2018-03-01

To investigate the utility of superb microvascular imaging (SMI) for evaluating the vascularity of breast masses in comparison with colour or power Doppler ultrasound (US) and the effect on diagnostic performance. A total of 191 biopsy-proven masses (99 benign and 92 malignant) in 166 women with greyscale, colour Doppler, power Doppler, and SMI images were enrolled in this retrospective study. Three radiologists analysed the vascular images using a three-factor scoring system to evaluate the number, morphology, and distribution of tumour vessels. They assessed the Breast Imaging-Reporting and Data System categories for greyscale US alone and combinations of greyscale US and each type of vascular US. The Kruskal-Wallis test was performed and the area under the receiver-operating characteristic curve (AUC) measured. On SMI, vascular scores were compared between benign and malignant masses and the optimal cut-off value for the overall score was determined. SMI showed higher vascular scores than colour or power Doppler US and malignant masses had higher scores than benign masses (ppower Doppler US (AUC, 0.815 versus 0.774, 0.789, 0.791; ppower Doppler US for characterising the vascularity in breast masses and improving diagnostic performance. Copyright © 2017 The Royal College of Radiologists. Published by Elsevier Ltd. All rights reserved.

Cardiac Time Intervals by Tissue Doppler Imaging M-Mode

DEFF Research Database (Denmark)

Biering-Sørensen, Tor; Mogelvang, Rasmus; de Knegt, Martina Chantal

2016-01-01

PURPOSE: To define normal values of the cardiac time intervals obtained by tissue Doppler imaging (TDI) M-mode through the mitral valve (MV). Furthermore, to evaluate the association of the myocardial performance index (MPI) obtained by TDI M-mode (MPITDI) and the conventional method of obtaining...

Steerable Doppler transducer probes

International Nuclear Information System (INIS)

Fidel, H.F.; Greenwood, D.L.

1986-01-01

An ultrasonic diagnostic probe is described which is capable of performing ultrasonic imaging and Doppler measurement consisting of: a hollow case having an acoustic window which passes ultrasonic energy and including chamber means for containing fluid located within the hollow case and adjacent to a portion of the acoustic window; imaging transducer means, located in the hollow case and outside the fluid chamber means, and oriented to direct ultrasonic energy through the acoustic window toward an area which is to be imaged; Doppler transducer means, located in the hollow case within the fluid chamber means, and movably oriented to direct Doppler signals through the acoustic window toward the imaged area; means located within the fluid chamber means and externally controlled for controllably moving the Doppler transducer means to select one of a plurality of axes in the imaged area along which the Doppler signals are to be directed; and means, located external to the fluid chamber means and responsive to the means for moving, for providing an indication signal for identifying the selected axis

Language Lateralization in Children Using Functional Transcranial Doppler Sonography

Science.gov (United States)

Haag, Anja; Moeller, Nicola; Knake, Susanne; Hermsen, Anke; Oertel, Wolfgang H.; Rosenow, Felix; Hamer, Hajo M.

2010-01-01

Aim: Language lateralization with functional transcranial Doppler sonography (fTCD) and lexical word generation has been shown to have high concordance with the Wada test and functional magnetic resonance imaging in adults. We evaluated a nonlexical paradigm to determine language dominance in children. Method: In 23 right-handed children (12…

Quantitative measurement of portal blood flow by magnetic resonance phase contrast. Comparative study of flow phantom and Doppler ultrasound in vivo

International Nuclear Information System (INIS)

Tsunoda, Masatoshi; Kimoto, Shin; Hamazaki, Keisuke; Takeda, Yoshihiro; Hiraki, Yoshio.

1994-01-01

A non-invasive method for measuring portal blood flow by magnetic resonance (MR) phase contrast was evaluated in a flow phantom and 20 healthy volunteers. In a flow phantom study, the flow volumes and mean flow velocities measured by MR phase contrast showed close correlations with those measured by electromagnetic flow-metry. In 20 healthy volunteers, the cross-sectional areas, flow volumes and mean flow velocities measured by MR phase contrast correlated well with those measured by the Doppler ultrasound method. Portal blood flow averaged during the imaging time could be measured under natural breathing conditions by using a large number of acquisitions without the limitations imposed on the Doppler ultrasound method. MR phase contrast is considered to be useful for the non-invasive measurement of portal blood flow. (author)

Three-dimensional power Doppler sonography: imaging and quantifying blood flow and vascularization.

Science.gov (United States)

Pairleitner, H; Steiner, H; Hasenoehrl, G; Staudach, A

1999-08-01

To assess the feasibility of imaging low-velocity blood flow in adnexal masses by transvaginal three-dimensional power Doppler sonography, to analyze three-dimensional power Doppler sonography data sets with a new computer-assisted method and to test the reproducibility of the technique. A commercially available 5-MHz Combison 530 ultrasound system was used to perform three-dimensional power Doppler sonography transvaginally. A cube (= volume of interest) was defined enclosing the vessels of the cyst and the Cartesian characteristics were stored on a hard disk. This cube was analyzed using specially designed software. Five indices representing vascularization (the vascularization index (VI) or blood flow (the flow index (FI)) or both (the vascularization-flow index (VFI)) were calculated. The intraobserver repeatability of cube definition and scan repetition was assessed using Hartley's test for homogeneous variances. Interobserver agreement was assessed by the Pearson correlation coefficient. Imaging of vessels with low-velocity blood flow by three-dimensional power Doppler sonography and cube definition was possible in all adnexal massed studied. In some cases even induced non-vascular flow related to endometriosis was detected. The calculated F value with intraobserver repeated Cartesian file-saving ranged from 0 to 18.8, with intraobserver scan repetition from 4.74 to 24.8 for VI, FI 1, FI 2 and VFI 1; for VFI 2 the calculated F value was 64. The interobserver correlation coefficient ranged between 0.83 and 0.92 for VI, FI 1, FI 2 and VFI 1; for VFI 2 the correlation coefficient was less than 0.75. Vessels with low-velocity blood flow can be imaged using three-dimensional power Doppler sonography. Induced non-vascular flow was detected in endometriotic cyst fluid. Three-dimensional power Doppler sonography combined with the cube method gave reproducible information for all indices except VFI 2. These indices might prove to be a new predictor in all fields of

New Approaches For Asteroid Spin State and Shape Modeling From Delay-Doppler Radar Images

Science.gov (United States)

Raissi, Chedy; Lamee, Mehdi; Mosiane, Olorato; Vassallo, Corinne; Busch, Michael W.; Greenberg, Adam; Benner, Lance A. M.; Naidu, Shantanu P.; Duong, Nicholas

2016-10-01

Delay-Doppler radar imaging is a powerful technique to characterize the trajectories, shapes, and spin states of near-Earth asteroids; and has yielded detailed models of dozens of objects. Reconstructing objects' shapes and spins from delay-Doppler data is a computationally intensive inversion problem. Since the 1990s, delay-Doppler data has been analyzed using the SHAPE software. SHAPE performs sequential single-parameter fitting, and requires considerable computer runtime and human intervention (Hudson 1993, Magri et al. 2007). Recently, multiple-parameter fitting algorithms have been shown to more efficiently invert delay-Doppler datasets (Greenberg & Margot 2015) - decreasing runtime while improving accuracy. However, extensive human oversight of the shape modeling process is still required. We have explored two new techniques to better automate delay-Doppler shape modeling: Bayesian optimization and a machine-learning neural network.One of the most time-intensive steps of the shape modeling process is to perform a grid search to constrain the target's spin state. We have implemented a Bayesian optimization routine that uses SHAPE to autonomously search the space of spin-state parameters. To test the efficacy of this technique, we compared it to results with human-guided SHAPE for asteroids 1992 UY4, 2000 RS11, and 2008 EV5. Bayesian optimization yielded similar spin state constraints within a factor of 3 less computer runtime.The shape modeling process could be further accelerated using a deep neural network to replace iterative fitting. We have implemented a neural network with a variational autoencoder (VAE), using a subset of known asteroid shapes and a large set of synthetic radar images as inputs to train the network. Conditioning the VAE in this manner allows the user to give the network a set of radar images and get a 3D shape model as an output. Additional development will be required to train a network to reliably render shapes from delay-Doppler

Real time 3D structural and Doppler OCT imaging on graphics processing units

Science.gov (United States)

Sylwestrzak, Marcin; Szlag, Daniel; Szkulmowski, Maciej; Gorczyńska, Iwona; Bukowska, Danuta; Wojtkowski, Maciej; Targowski, Piotr

2013-03-01

In this report the application of graphics processing unit (GPU) programming for real-time 3D Fourier domain Optical Coherence Tomography (FdOCT) imaging with implementation of Doppler algorithms for visualization of the flows in capillary vessels is presented. Generally, the time of the data processing of the FdOCT data on the main processor of the computer (CPU) constitute a main limitation for real-time imaging. Employing additional algorithms, such as Doppler OCT analysis, makes this processing even more time consuming. Lately developed GPUs, which offers a very high computational power, give a solution to this problem. Taking advantages of them for massively parallel data processing, allow for real-time imaging in FdOCT. The presented software for structural and Doppler OCT allow for the whole processing with visualization of 2D data consisting of 2000 A-scans generated from 2048 pixels spectra with frame rate about 120 fps. The 3D imaging in the same mode of the volume data build of 220 × 100 A-scans is performed at a rate of about 8 frames per second. In this paper a software architecture, organization of the threads and optimization applied is shown. For illustration the screen shots recorded during real time imaging of the phantom (homogeneous water solution of Intralipid in glass capillary) and the human eye in-vivo is presented.

Doppler time-of-flight imaging

KAUST Repository

Heide, Felix

2015-07-30

Over the last few years, depth cameras have become increasingly popular for a range of applications, including human-computer interaction and gaming, augmented reality, machine vision, and medical imaging. Many of the commercially-available devices use the time-of-flight principle, where active illumination is temporally coded and analyzed on the camera to estimate a per-pixel depth map of the scene. In this paper, we propose a fundamentally new imaging modality for all time-of-flight (ToF) cameras: per-pixel velocity measurement. The proposed technique exploits the Doppler effect of objects in motion, which shifts the temporal frequency of the illumination before it reaches the camera. Using carefully coded illumination and modulation frequencies of the ToF camera, object velocities directly map to measured pixel intensities. We show that a slight modification of our imaging system allows for color, depth, and velocity information to be captured simultaneously. Combining the optical flow computed on the RGB frames with the measured metric axial velocity allows us to further estimate the full 3D metric velocity field of the scene. We believe that the proposed technique has applications in many computer graphics and vision problems, for example motion tracking, segmentation, recognition, and motion deblurring.

Quaternion-based transformation for extraction of image-generating Doppler for ISAR

CSIR Research Space (South Africa)

Abdul Gaffar, MY

2008-10-01

Full Text Available contributing motion that is useful to the ISAR imaging process; the contributing motion consists of the Doppler generating axis and the effective angle of rotation. This letter presents a quaternion-based transformation that converts measured attitude...

High-frequency dual mode pulsed wave Doppler imaging for monitoring the functional regeneration of adult zebrafish hearts

OpenAIRE

Kang, Bong Jin; Park, Jinhyoung; Kim, Jieun; Kim, Hyung Ham; Lee, Changyang; Hwang, Jae Youn; Lien, Ching-Ling; Shung, K. Kirk

2015-01-01

Adult zebrafish is a well-known small animal model for studying heart regeneration. Although the regeneration of scars made by resecting the ventricular apex has been visualized with histological methods, there is no adequate imaging tool for tracking the functional recovery of the damaged heart. For this reason, high-frequency Doppler echocardiography using dual mode pulsed wave Doppler, which provides both tissue Doppler (TD) and Doppler flow in a same cardiac cycle, is developed with a 30 ...

4-D flow magnetic resonance imaging: blood flow quantification compared to 2-D phase-contrast magnetic resonance imaging and Doppler echocardiography

Energy Technology Data Exchange (ETDEWEB)

Gabbour, Maya [Ann and Robert H. Lurie Children' s Hospital of Chicago, Department of Medical Imaging 9, Chicago, IL (United States); Schnell, Susanne [Northwestern University Feinberg School of Medicine, Department of Radiology, Chicago, IL (United States); Jarvis, Kelly [Northwestern University, Department of Biomedical Engineering, McCormick School of Engineering, Evanston, IL (United States); Robinson, Joshua D. [Ann and Robert H. Lurie Children' s Hospital of Chicago, Department of Pediatrics, Division of Pediatric Cardiology, Chicago, IL (United States); Northwestern University Feinberg School of Medicine, Department of Pediatrics, Chicago, IL (United States); Markl, Michael [Northwestern University Feinberg School of Medicine, Department of Radiology, Chicago, IL (United States); Northwestern University, Department of Biomedical Engineering, McCormick School of Engineering, Evanston, IL (United States); Rigsby, Cynthia K. [Ann and Robert H. Lurie Children' s Hospital of Chicago, Department of Medical Imaging 9, Chicago, IL (United States); Northwestern University Feinberg School of Medicine, Department of Radiology, Chicago, IL (United States)

2015-06-15

Doppler echocardiography (echo) is the reference standard for blood flow velocity analysis, and two-dimensional (2-D) phase-contrast magnetic resonance imaging (MRI) is considered the reference standard for quantitative blood flow assessment. However, both clinical standard-of-care techniques are limited by 2-D acquisitions and single-direction velocity encoding and may make them inadequate to assess the complex three-dimensional hemodynamics seen in congenital heart disease. Four-dimensional flow MRI (4-D flow) enables qualitative and quantitative analysis of complex blood flow in the heart and great arteries. The objectives of this study are to compare 4-D flow with 2-D phase-contrast MRI for quantification of aortic and pulmonary flow and to evaluate the advantage of 4-D flow-based volumetric flow analysis compared to 2-D phase-contrast MRI and echo for peak velocity assessment in children and young adults. Two-dimensional phase-contrast MRI of the aortic root, main pulmonary artery (MPA), and right and left pulmonary arteries (RPA, LPA) and 4-D flow with volumetric coverage of the aorta and pulmonary arteries were performed in 50 patients (mean age: 13.1 ± 6.4 years). Four-dimensional flow analyses included calculation of net flow and regurgitant fraction with 4-D flow analysis planes similarly positioned to 2-D planes. In addition, 4-D flow volumetric assessment of aortic root/ascending aorta and MPA peak velocities was performed and compared to 2-D phase-contrast MRI and echo. Excellent correlation and agreement were found between 2-D phase-contrast MRI and 4-D flow for net flow (r = 0.97, P < 0.001) and excellent correlation with good agreement was found for regurgitant fraction (r = 0.88, P < 0.001) in all vessels. Two-dimensional phase-contrast MRI significantly underestimated aortic (P = 0.032) and MPA (P < 0.001) peak velocities compared to echo, while volumetric 4-D flow analysis resulted in higher (aortic: P = 0.001) or similar (MPA: P = 0.98) peak

Clinical utility of eco-color-power Doppler ultrasonography and contrast enhanced magnetic resonance imaging for interpretation and quantification of joint synovitis: a review.

Science.gov (United States)

Carotti, Marina; Galeazzi, Vittoria; Catucci, Francesca; Zappia, Marcello; Arrigoni, Francesco; Barile, Antonio; Giovagnoni, Andrea

2018-01-19

With the introduction of new biologics such as anti-TNF-alpha antibodies and other therapies in the treatment of inflammatory arthritis, capable of halting joint destruction and functional disability, there are new pressures on diagnostic and prognostic imaging. Early demonstration of pre-erosive inflammatory features and monitoring of the long-term effects of treatment are becoming increasingly important. Early detection of synovitis offers advantages in terms of allowing early instigation of therapy and may allow the identification of those patients displaying more aggressive disease who might benefit from early intervention with expensive DMARD therapy. Advanced imaging techniques such as ultrasound (US) and magnetic resonance imaging (MRI) have focussed on the demonstration and quantification of synovitis and allow early diagnosis of inflammatory arthropathies such as rheumatoid arthritis (RA) and psoriatic arthritis (PsA). Synovitis represents a potential surrogate measure of disease activity that can be monitored using either MRI or US; the techniques have, generally, focused on monitoring synovial volume or quality as assessed by its vascularity. However to achieve these goals, standardisation and validation of US and MRI are required to ensure accurate diagnosis, reproducibility and reliability. Each modality has different strengths and weaknesses and levels of validation. This article aims to increase the awareness of radiologists and rheumatologists about this field and to encourage them to participate and contribute to the ongoing development of these modalities. Without this collaboration, it is unlikely that these modalities will reach their full potential in the field of rheumatological imaging. This review is in two parts. The first part addresses the role of US and colour or power Doppler sonography (PDUS) in the detection and monitoring of synovitis in inflammatory arthropathies. The second part will look at advanced MR imaging and Dynamic contrast

Hypercholesterolemia and Myocardial function evaluated via Tissue Doppler Imaging

Directory of Open Access Journals (Sweden)

Kotaru Pavan

2009-11-01

Full Text Available Abstract Objective To establish a link between hypercholesterolemia and myocardial dysfunction. Background Heart failure is a complex disease involving changes in systolic and diastolic function. Newer echocardiographic imaging modalities may be able to detect discreet changes in myocardial function associated with hypercholesterolemia. Therefore we sought to establish a link between hypercholesterolemia and myocardial dysfunction with tissue Doppler imaging (TDI. Methods Twenty-seven rabbits were studied: 7 were fed normal chow (group 1 and 20 a high cholesterol diet (10 with ezetimibe, 1 mg/kg/day; group 2 and 10 without, group 3. Echocardiographic images were obtained under general anesthesia. Serum cholesterol levels were obtained at baseline, 3 and 6 months and myocardial cholesterol levels measured following euthanasia. Results Doppler measurements, including E/A, E'/A' and S' were significantly lower in group 3 compared to both groups 1 and 2 but no significant differences were noted in chamber sizes or ejection fraction among the groups. Average serum cholesterol was higher in group 3 compared to groups 1 and 2 respectively (495 ± 305 mg/dl vs. 114 ± 95 mg/dl and 87 ± 37 mg/dl; p 2 = 0.17 p = 0.04, r2 = 0.37 p = 0.001 and r2 = 0.24 p = 0.01. Conclusion Cholesterol load in the serum and myocardium was significantly associated with decreased systolic and diastolic function by TDI. Moreover, lipid lowering was protective.

Tissue Doppler Imaging in the evaluation of abdominal aortic pulsatility: a useful tool for the neonatologist.

Science.gov (United States)

Valerio, Enrico; Grison, Alessandra; Capretta, Anna; Golin, Rosanna; Ferrarese, Paola; Bellettato, Massimo

2017-03-01

Sonographic cardiac evaluation of newborns with suspected aortic coarctation (AoC) should tend to demonstrate a good phasic and pulsatile flow and the absence of pressure gradient along a normally conformed aortic arch from the modified left parasternal and suprasternal echocardiographic views; these findings, however, may not necessarily rule out a more distal coarctation in the descending aorta. For this reason, the sonographic exam of newborns with suspected AoC should always include a Doppler evaluation of abdominal aortic blood flow from the subcostal view. Occasionally, however, a clearly pulsatile Doppler flow trace in abdominal aorta may be difficult to obtain due to the bad insonation angle existing between the probe and the vessel. In such suboptimal ultrasonic alignment situation, the use of Tissue Doppler Imaging instead of classic Doppler flow imaging may reveal a preserved aortic pulsatility by sampling the aortic wall motion induced by normal flow. We propose to take advantage of the TDI pattern as a surrogate of a normal pulsatile Doppler flow trace in abdominal aorta when the latter is difficult to obtain due to malalignment with the insonated vessel.

Doppler time-of-flight imaging

KAUST Repository

Heidrich, Wolfgang

2017-02-16

Systems and methods for imaging object velocity are provided. In an embodiment, at least one Time-of-Flight camera is used to capture a signal representative of an object in motion over an exposure time. Illumination and modulation frequency of the captured motion are coded within the exposure time. A change of illumination frequency is mapped to measured pixel intensities of the captured motion within the exposure time, and information about a Doppler shift in the illumination frequency is extracted to obtain a measurement of instantaneous per pixel velocity of the object in motion. The radial velocity information of the object in motion can be simultaneously captured for each pixel captured within the exposure time. In one or more aspects, the illumination frequency can be coded orthogonal to the modulation frequency of the captured motion. The change of illumination frequency can correspond to radial object velocity.

MRI (Magnetic Resonance Imaging)

Science.gov (United States)

... Procedures Medical Imaging MRI (Magnetic Resonance Imaging) MRI (Magnetic Resonance Imaging) Share Tweet Linkedin Pin it More sharing options Linkedin Pin it Email Print Magnetic Resonance Imaging (MRI) is a medical imaging procedure for ...

Avaliação dos tumores hepáticos ao Doppler Doppler evaluation of liver tumors

Directory of Open Access Journals (Sweden)

Márcio Martins Machado

2004-10-01

Full Text Available Os avanços recentes na ultra-sonografia têm ampliado a possibilidade de detecção de tumores hepáticos. Isto tem auxiliado na perspectiva de melhora do prognóstico destes pacientes, à medida que novas técnicas terapêuticas têm surgido. Neste artigo os autores relatam achados ao Doppler que podem auxiliar na identificação e caracterização dos tumores hepáticos, avaliando dados do Doppler colorido, pulsado e do Doppler de amplitude ("power Doppler". Fazem, também, referência a novas modalidades de imagem, como o uso da harmônica.Recent advances in ultrasound have optimized the detection of liver tumors and helped to improve the prognosis of patients with this condition as newly developed and improved therapeutic modalities have been established. The authors review important Doppler findings which may help in the identification and characterization of some hepatic tumors through the evaluation of color Doppler, pulsed Doppler and power Doppler features. New imaging methods such as the use of harmonics imaging are also reviewed.

Screening for stroke in sickle cell anemia: comparison of transcranial Doppler imaging and nonimaging US techniques.

Science.gov (United States)

Neish, Ariane S; Blews, David E; Simms, Catherine A; Merritt, Robert K; Spinks, Alice J

2002-03-01

To determine whether criteria for screening patients with sickle cell anemia for stroke established with a nonimaging transcranial Doppler ultrasonographic (US) technique are applicable to studies performed with a transcranial Doppler US imaging technique. One hundred sixty-eight examinations in 66 children were performed for sickle cell stroke screening. Children were examined with nonimaging and imaging transcranial Doppler US techniques on the same day, for a total of 84 paired examinations. The time-averaged maximum mean velocity (V(mean)) and resistive index (RI) were calculated in the middle cerebral arteries, bifurcations of the distal internal carotid arteries, distal internal carotid arteries, anterior cerebral arteries, posterior cerebral arteries, and basilar arteries. The maximum systolic velocity (V(max)) was evaluated in the distal internal carotid arteries and middle cerebral arteries. V(mean), V(max), and RI measurements were subjected to repeated-measures multivariate analysis of covariance, and the Pearson product moment correlation was used for middle cerebral artery velocity, age, and hemoglobin. V(mean) measurements obtained with nonimaging and imaging techniques varied substantially for the bifurcation of the distal internal carotid artery, the posterior cerebral artery, and the basilar artery. Substantial differences were found in RIs for every vessel. Examination time was shorter with the nonimaging technique. V(mean) measurements in the middle cerebral artery, distal internal carotid artery, and anterior cerebral artery did not vary substantially between nonimaging and imaging transcranial Doppler US. RI data did not yield comparable measurements.

Stellar magnetometry and Zeeman-Doppler imaging in exo-planets research using the radial velocity method

International Nuclear Information System (INIS)

Hebrard, Elodie

2015-01-01

Forthcoming instruments dedicated to exo-planets detection through the radial velocity method are numerous, and increasingly more accurate. However this method is indirect: orbiting planets are detected and characterised from variations on the spectrum of the host star. We are therefore sensitive to all activity phenomena impacting the spectrum and producing a radial velocity signal (pulsation, granulation, spots, magnetic cycle...). The detection of rocky Earth-like planets around main-sequence stars, and of hot Jupiters into young systems, are currently limited by the intrinsic magnetic activity of the host stars. The radial velocity fluctuations caused by activity (activity jitter) can easily mimic and hide signals from such planets, whose amplitude is of a few m/s and hundreds of m/s, respectively. As a result, the detection threshold of exo-planets is largely set by the stellar activity level. Currently, efforts are invested to overcome this intrinsic limitation. During my PhD, I studied how to take advantage of imaging tomographic techniques (Zeeman-Doppler imaging, ZDI) to characterize stellar activity and magnetic field topologies, ultimately allowing us to filter out the activity jitter. My work is based on spectro-polarimetric observations of a sample of weakly-active M-dwarfs, and young active T Tauri stars. Using a modified version of ZDI, we are able to reconstruct the distribution of active regions, and then model the induced stellar signal allowing us to clean RV curves from the activity jitter. First tests demonstrate that this technique can be efficient enough to recover the planet signal, especially for the more active ones. (author)

Cardiac Time Intervals Measured by Tissue Doppler Imaging M-mode

DEFF Research Database (Denmark)

Biering-Sørensen, Tor; Møgelvang, Rasmus; Schnohr, Peter

2016-01-01

function was evaluated in 1915 participants by using both conventional echocardiography and tissue Doppler imaging (TDI). The cardiac time intervals, including the isovolumic relaxation time (IVRT), isovolumic contraction time (IVCT), and ejection time (ET), were obtained by TDI M-mode through the mitral......). Additionally, they displayed a significant dose-response relationship, between increasing severity of elevated blood pressure and increasing left ventricular mass index (P

High PRF ultrafast sliding compound doppler imaging: fully qualitative and quantitative analysis of blood flow

Science.gov (United States)

Kang, Jinbum; Jang, Won Seuk; Yoo, Yangmo

2018-02-01

Ultrafast compound Doppler imaging based on plane-wave excitation (UCDI) can be used to evaluate cardiovascular diseases using high frame rates. In particular, it provides a fully quantifiable flow analysis over a large region of interest with high spatio-temporal resolution. However, the pulse-repetition frequency (PRF) in the UCDI method is limited for high-velocity flow imaging since it has a tradeoff between the number of plane-wave angles (N) and acquisition time. In this paper, we present high PRF ultrafast sliding compound Doppler imaging method (HUSDI) to improve quantitative flow analysis. With the HUSDI method, full scanline images (i.e. each tilted plane wave data) in a Doppler frame buffer are consecutively summed using a sliding window to create high-quality ensemble data so that there is no reduction in frame rate and flow sensitivity. In addition, by updating a new compounding set with a certain time difference (i.e. sliding window step size or L), the HUSDI method allows various Doppler PRFs with the same acquisition data to enable a fully qualitative, retrospective flow assessment. To evaluate the performance of the proposed HUSDI method, simulation, in vitro and in vivo studies were conducted under diverse flow circumstances. In the simulation and in vitro studies, the HUSDI method showed improved hemodynamic representations without reducing either temporal resolution or sensitivity compared to the UCDI method. For the quantitative analysis, the root mean squared velocity error (RMSVE) was measured using 9 angles (-12° to 12°) with L of 1-9, and the results were found to be comparable to those of the UCDI method (L  =  N  =  9), i.e.  ⩽0.24 cm s-1, for all L values. For the in vivo study, the flow data acquired from a full cardiac cycle of the femoral vessels of a healthy volunteer were analyzed using a PW spectrogram, and arterial and venous flows were successfully assessed with high Doppler PRF (e.g. 5 kHz at L�

High PRF ultrafast sliding compound doppler imaging: fully qualitative and quantitative analysis of blood flow.

Science.gov (United States)

Kang, Jinbum; Jang, Won Seuk; Yoo, Yangmo

2018-02-09

Ultrafast compound Doppler imaging based on plane-wave excitation (UCDI) can be used to evaluate cardiovascular diseases using high frame rates. In particular, it provides a fully quantifiable flow analysis over a large region of interest with high spatio-temporal resolution. However, the pulse-repetition frequency (PRF) in the UCDI method is limited for high-velocity flow imaging since it has a tradeoff between the number of plane-wave angles (N) and acquisition time. In this paper, we present high PRF ultrafast sliding compound Doppler imaging method (HUSDI) to improve quantitative flow analysis. With the HUSDI method, full scanline images (i.e. each tilted plane wave data) in a Doppler frame buffer are consecutively summed using a sliding window to create high-quality ensemble data so that there is no reduction in frame rate and flow sensitivity. In addition, by updating a new compounding set with a certain time difference (i.e. sliding window step size or L), the HUSDI method allows various Doppler PRFs with the same acquisition data to enable a fully qualitative, retrospective flow assessment. To evaluate the performance of the proposed HUSDI method, simulation, in vitro and in vivo studies were conducted under diverse flow circumstances. In the simulation and in vitro studies, the HUSDI method showed improved hemodynamic representations without reducing either temporal resolution or sensitivity compared to the UCDI method. For the quantitative analysis, the root mean squared velocity error (RMSVE) was measured using 9 angles (-12° to 12°) with L of 1-9, and the results were found to be comparable to those of the UCDI method (L  =  N  =  9), i.e.  ⩽0.24 cm s -1 , for all L values. For the in vivo study, the flow data acquired from a full cardiac cycle of the femoral vessels of a healthy volunteer were analyzed using a PW spectrogram, and arterial and venous flows were successfully assessed with high Doppler PRF (e.g. 5 kHz at L�

[Role of cardiac magnetic resonance in cardiac involvement of Fabry disease].

Science.gov (United States)

Serra, Viviana M; Barba, Miguel Angel; Torrá, Roser; Pérez De Isla, Leopoldo; López, Mónica; Calli, Andrea; Feltes, Gisela; Torras, Joan; Valverde, Victor; Zamorano, José L

2010-09-04

Fabry disease is a hereditary disorder. Clinical manifestations are multisystemic. The majority of the patients remain undiagnosed until late in life, when alterations could be irreversible. Early detection of cardiac symptoms is of major interest in Fabry's disease (FD) in order to gain access to enzyme replacement therapy. Echo-Doppler tissular imaging (TDI) has been used as a cardiologic early marker in FD. This study is intended to determine whether the cardiac magnetic resonance is as useful tool as TDI for the early detection of cardiac affectation in FD. Echocardiography, tissue Doppler and Cardio magnetic resonance was performed in 20 patients with confirmed Fabry Disease. Left ventricular hypertrophy was defined as septum and left ventricular posterior wall thickness ≥12 mm. An abnormal TDI velocity was defined as (Sa), (Ea) and/or (Aa) velocities gadolinium-enhanced images sequences were obtained using magnetic resonance. Twenty patients included in the study were divided into three groups: 1. Those without left ventricular hypertrophy nor tissue Doppler impairment 2. Those without left ventricular hypertrophy and tissue Doppler impairment 3. Those with left ventricular hypertrophy and Tissue Doppler impairment. Late gadolinium enhancement was found in only one patient, who has already altered DTI and LVH. Tissue Doppler imaging (TDI) is the only diagnostic tool able to provide early detection of cardiac affectation in patients with FD. Magnetic resonance provides information of the disease severity in patients with LVH, but can not be used as an early marker of cardiac disease in patients with FD. However MRI could be of great value for diagnostic stratification. Copyright © 2009 Elsevier España, S.L. All rights reserved.

High-frequency dual mode pulsed wave Doppler imaging for monitoring the functional regeneration of adult zebrafish hearts

Science.gov (United States)

Kang, Bong Jin; Park, Jinhyoung; Kim, Jieun; Kim, Hyung Ham; Lee, Changyang; Hwang, Jae Youn; Lien, Ching-Ling; Shung, K. Kirk

2015-01-01

Adult zebrafish is a well-known small animal model for studying heart regeneration. Although the regeneration of scars made by resecting the ventricular apex has been visualized with histological methods, there is no adequate imaging tool for tracking the functional recovery of the damaged heart. For this reason, high-frequency Doppler echocardiography using dual mode pulsed wave Doppler, which provides both tissue Doppler (TD) and Doppler flow in a same cardiac cycle, is developed with a 30 MHz high-frequency array ultrasound imaging system. Phantom studies show that the Doppler flow mode of the dual mode is capable of measuring the flow velocity from 0.1 to 15 cm s−1 with high accuracy (p-value = 0.974 > 0.05). In the in vivo study of zebrafish, both TD and Doppler flow signals were simultaneously obtained from the zebrafish heart for the first time, and the synchronized valve motions with the blood flow signals were identified. In the longitudinal study on the zebrafish heart regeneration, the parameters for diagnosing the diastolic dysfunction, for example, E/Em < 10, E/A < 0.14 for wild-type zebrafish, were measured, and the type of diastolic dysfunction caused by the amputation was found to be similar to the restrictive filling. The diastolic function was fully recovered within four weeks post-amputation. PMID:25505135

Cost-effectiveness of laser Doppler imaging in burn care in the Netherlands

NARCIS (Netherlands)

M.J. Hop (M. Jenda); J. Hiddingh (J.); C.M. Stekelenburg (C.); H.C. Kuipers (Hester); E. Middelkoop (Esther); M. Nieuwenhuis (Marianne); S. Polinder (Suzanne); M.E. van Baar (Margriet)

2013-01-01

textabstractBackground: Early accurate assessment of burn depth is important to determine the optimal treatment of burns. The method most used to determine burn depth is clinical assessment, which is the least expensive, but not the most accurate.Laser Doppler imaging (LDI) is a technique with which

Standardised imaging technique for guided M-mode and Doppler echocardiography in the horse.

Science.gov (United States)

Long, K J; Bonagura, J D; Darke, P G

1992-05-01

Eighteen echocardiographic images useful for diagnostic imaging, M-mode echocardiography, and Doppler echocardiography of the equine heart were standardised by relating the position of the axial beam to various intracardiac landmarks. The transducer orientation required for each image was recorded in 14 adult horses by describing the degree of sector rotation and the orientation of the axial beam relative to the thorax. Repeatable images could be obtained within narrow limits of angulation and rotation for 14 of the 18 standardised images evaluated. Twenty-seven National Hunt horses were subsequently examined using this standardised technique. Selected cardiac dimensions were measured from two-dimensional and guided M-mode studies. Satisfactory results were achieved in 26 of the 27 horses. There was no linear correlation between any of the measured cardiac values and bodyweight. There was no significant difference between measurements taken from the left and the right hemithorax. Six horses were imaged on three consecutive days to assess the repeatability of the measurements. No significant difference was found between measurements obtained on different days. This study demonstrates a method for standardised echocardiographic evaluation of the equine heart that is repeatable, valuable for teaching techniques of equine echocardiography, applicable for diagnostic imaging and quantification of cardiac size, and useful for the evaluation of blood-flow patterns by Doppler ultrasound.

Magnetic resonance imaging

International Nuclear Information System (INIS)

Anon.

1988-01-01

Magnetic resonance imaging (MRI) is a new and innovative technique that affords anatomic images in multiple planes and that may provide information about tissue characterization. The magnetic resonance images are obtained by placing the patient or the area of interest within a powerful, highly uniform, static magnetic field. Magnetized protons (hydrogen nuclei) within the patient align like small magnets in this field. Radiofrequency pulses are then used to create an oscillating magnetic field perpendicular to the main field. Magnetic resonance images differ from those produced by x-rays: the latter are associated with absorption of x-ray energy while magnetic resonance images are based on proton density and proton relaxation dynamics. Proton characteristics vary according to the tissue under examination and reflect its physical and chemical properties. To resolve issues regarding safety and efficacy, the Warren Grant Magnuson Clinical Center and the Office of Medical Applications of Research of the National Institutes of Health (NIH) convened a consensus conference about MRI Oct 26 through 28, 1987. At the NIH, the Consensus Development Conference brings together investigators in the biomedical sciences, clinical investigators, practicing physicians, and consumer and special interest groups to make a scientific assessment of technologies, including drugs, devices, and procedures, and to seek agreement on their safety and effectiveness

Characterization of benign and malignant solid breast masses in harmonic 3D power Doppler imaging

International Nuclear Information System (INIS)

Hsiao, Y.-H.; Huang, Y.-L.; Kuo, S.-J.; Liang, W.-M.; Chen, S.-T.; Chen, D.-R.

2009-01-01

Purpose: The authors assessed the characteristics of benign and malignant solid breast tumors in harmonic three-dimensional (3D) power Doppler imaging and proposed decision models to classify benign and malignant breast tumors. Materials and methods: A total of 86 malignant and 97 benign harmonic 3D power Doppler US images were analyzed. All the harmonic 3D power Doppler images were obtained using a Voluson730 US system (GE, Zipf, Austria) equipped with a RSP 6-12 transducer and tissue harmonic imaging modalities. Imaging analysis was performed using the Virtual Organ Computer-aided Analysis (VOCAL)-imaging program. Histogram indices, the vascularization index (VI), flow index (FI) and vascularization-flow index (VFI), were calculated for the intra-tumor and for shells with an outside thickness of 3 mm surrounding the breast tumors. The receiver operating characteristic (ROC) curves were calculated to estimate the diagnostic performances. Results: The results revealed that the choice of decision model comprised the parameters of patient age, intra-tumor VI, and tumor volume to classify benign and malignant breast tumors. The area under the ROC curve (Az) was 0.910, accuracy was 81.4%, and sensitivity and specificity were 81.4% and 81.4%, respectively. The parameter intra-tumor VI was the choice for all of the histogram indices in differentiating between malignant and benign lesions. Conclusion: The decision model, which was composed of patient age, tumor volume and intra-tumor VI, and a cut-off value for intra-tumor VI at the upper end of patient age and tumor volume, was recommended in clinical application.

Cost-effectiveness of laser Doppler imaging in burn care in the Netherlands

NARCIS (Netherlands)

Hop, M.J.; Hiddingh, J.; Stekelenburg, C.; Kuipers, H.C.; Middelkoop, E.; Nieuwenhuis, M.K.; Polinder, S.; van Baar, M.E.

2013-01-01

Background: Early accurate assessment of burn depth is important to determine the optimal treatment of burns. The method most used to determine burn depth is clinical assessment, which is the least expensive, but not the most accurate.Laser Doppler imaging (LDI) is a technique with which a more

Pediatric magnetic resonance imaging

International Nuclear Information System (INIS)

Cohen, M.D.

1986-01-01

This book defines the current clinical potential of magnetic resonance imaging and focuses on direct clinical work with pediatric patients. A section dealing with the physics of magnetic resonance imaging provides an introduction to enable clinicians to utilize the machine and interpret the images. Magnetic resonance imaging is presented as an appropriate imaging modality for pediatric patients utilizing no radiation

Magnetic resonance imaging apparatus

International Nuclear Information System (INIS)

Ehnholm, G.J.

1991-01-01

This patent describes an electron spin resonance enhanced magnetic resonance (MR) imaging (ESREMRI) apparatus able to generate a primary magnetic field during periods of nuclear spin transition excitation and magnetic resonance signal detection. This allows the generation of ESREMRI images of a subject. A primary magnetic field of a second and higher value generated during periods of nuclear spin transition excitation and magnetic resonance signal detection can be used to generate conventional MR images of a subject. The ESREMRI and native MR images so generated may be combined, (or superimposed). (author)

Comparative cardiac imaging

International Nuclear Information System (INIS)

Brundage, B.H.

1990-01-01

This book is designed to compare all major cardiac imaging techniques. All major imaging techniques - including conventional angiography, digital angiography, echocardiography and Doppler imaging, conventional radioisotope techniques, computed tomography, and magnetic resonance imaging - are covered in this text as they apply to the major cardiovascular disorders. There is brief coverage of positron emission tomography and an extensive presentation of ultrafast computed tomography

In-vivo imaging of blood flow in human retinal vessels using color Doppler optical coherence tomography

Science.gov (United States)

Yazdanfar, Siavash; Rollins, Andrew M.; Izatt, Joseph A.

1999-04-01

Quantification of retinal blood flow may lead to a better understanding of the progression and treatment of several ocular disorders, including diabetic retinopathy, age- related macular degeneration, and glaucoma. Current techniques, such as fluorescein angiography and laser Doppler velocimetry are limited, failing to provide sufficient information to the clinician. Color Doppler optical coherence tomography (CDOCT) is a novel technique using coherent heterodyne detection for simultaneous cross- sectional imaging of tissue microstructure and blood flow. This technique is capable of high spatial and velocity resolution imaging in highly scattering media. We implemented CDOCT for retinal blood flow mapping in human subjects. No dilation of the pupil was necessary. CDOCT is demonstrated for determining bidirectional flow in sub- 100micrometers diameter vessels in the retina. Additionally, we calculated Doppler broadening using the variance of depth- resolved spectra to identify regions with large velocity gradients within the Xenopus heart. This technique may be useful in quantifying local tissue perfusion in highly vascular retinal tissue.

The image of urachus adenocarcinoma on Doppler ultrasonography

Energy Technology Data Exchange (ETDEWEB)

Oyar, Orhan E-mail: o_oyar@hotmail.com; Yesildag, Ahmet; Gulsoy, Ufuk Kemal; Perk, Hakki

2002-10-01

Malignant urachal lesions are exceedingly rare and occur predominantly in adult life. In this case report, an adult patient with urachal carcinoma is presented with abdominal plain film, intravenous urography, gray-scale ultrasonography (US), Doppler US, and computed tomography (CT). Doppler US successfully showed the neovascularity with low resistive index value in the urachus tumor. We believe that Doppler US examination is helpful in the differential diagnosis of urachal carcinoma.

MR imaging of multiple fibroadenoma in breast: comparison with color doppler images and histologic findings

Energy Technology Data Exchange (ETDEWEB)

Chung, Soo Young; Yang, Ik; Park, Hai Jung; Lee, Yul; Chung, Bong Wha; Ahn, Hye Kyung [Hallym Univ. College of Medicine, Seoul (Korea, Republic of)

1997-10-01

To understand the different signal intensities seen on contrast enhanced magnetic resonance imaging (MRI) in multiple fibroadenoma of the breast, and to compare these with color Doppler ultrasonographic (CDUS) and histologic findings. MRI (1.0 Tesla, TIWI, T2WI, 3D-gradient echo dynamic contrast enhancement study) findings of 24 histologically proven cases of fibroadenoma in five patients were evaluated and compared with the histologic components (myxoid, adenomatous, fibrous). In addition, vascular flow, as seen on CDUS and histologic section, was compared. The observed degree of signal intensity waw classified into three groups, as follows: negative, 8.3%, mild to moderate, 54.2%; marked, 37.5%. On histologic section, the greater the fibrotic component, the higher the intensity of MRI enhancement, the greater the glandular component, and the intensity. CDUS showed vascular flow in only one tumor larger than 3cm in diameter. Vascular patterns of tumors on CDUS were dots in mass and detouring pattern, but in this case and in strongly enhanced cases, tumor vascularity-as seen on histologic section-showed no significant increase. Different signal intensities seen on contrast enhanced MRI in multiple fibroadenoma of the breast may be related more to the amount of glandular and fibrotic component than to increased tumor vascularity.

MR imaging of multiple fibroadenoma in breast: comparison with color doppler images and histologic findings

International Nuclear Information System (INIS)

Chung, Soo Young; Yang, Ik; Park, Hai Jung; Lee, Yul; Chung, Bong Wha; Ahn, Hye Kyung

1997-01-01

To understand the different signal intensities seen on contrast enhanced magnetic resonance imaging (MRI) in multiple fibroadenoma of the breast, and to compare these with color Doppler ultrasonographic (CDUS) and histologic findings. MRI (1.0 Tesla, TIWI, T2WI, 3D-gradient echo dynamic contrast enhancement study) findings of 24 histologically proven cases of fibroadenoma in five patients were evaluated and compared with the histologic components (myxoid, adenomatous, fibrous). In addition, vascular flow, as seen on CDUS and histologic section, was compared. The observed degree of signal intensity waw classified into three groups, as follows: negative, 8.3%, mild to moderate, 54.2%; marked, 37.5%. On histologic section, the greater the fibrotic component, the higher the intensity of MRI enhancement, the greater the glandular component, and the intensity. CDUS showed vascular flow in only one tumor larger than 3cm in diameter. Vascular patterns of tumors on CDUS were dots in mass and detouring pattern, but in this case and in strongly enhanced cases, tumor vascularity-as seen on histologic section-showed no significant increase. Different signal intensities seen on contrast enhanced MRI in multiple fibroadenoma of the breast may be related more to the amount of glandular and fibrotic component than to increased tumor vascularity

Patient-exposure data for doppler ultrasound

International Nuclear Information System (INIS)

Stewart, H.F.; Silvis, P.X.; Smith, S.W.

1986-01-01

In recent years ultrasound imaging and Doppler blood flow measurements have become important tools for use in diagnostic medicine. Commercial pulse-echo imaging equipment was first introduced into commerce in 1963. The first commercial continuous wave Doppler unit was introduced to the marketplace in 1966. As equipment improved and applications developed, the industry experienced rapid growth in the 1970s. One of the more recent growth areas in the application of diagnostic ultrasound has been the use of pulsed Doppler equipment for cardiac applications. Prior to 1976, some continuous wave Doppler ultrasound was used for cardiovascular diagnosis. However, only a single manufacturer marketed a pulsed Doppler clinical instrument for cardiac or peripheral vascular diagnosis. Currently, many continuous wave and pulsed Doppler instruments are commercially available for both peripheral vascular and cardiac diagnosis. This chapter (1) briefly reviews current safety guidelines, regulations, and recommendations for diagnostic ultrasound; (2) discusses the patient-exposure intensities associated with Doppler ultrasound medical equipment and compare these levels of exposure with intensities from other medical ultrasound devices; and (3) considers some of the current information as it relates to the safety of diagnostic ultrasound

SCANDI – an all-sky Doppler imager for studies of thermospheric spatial structure

Directory of Open Access Journals (Sweden)

A. L. Aruliah

2010-02-01

Full Text Available A new all-sky Fabry-Perot Interferometer called the Scanning Doppler Imager (SCANDI was built and installed at Longyearbyen in December 2006. Observations have been made of the Doppler shifts and Doppler broadening of the 630 nm airglow and aurora, from which upper thermospheric winds and temperatures are calculated. SCANDI allows measurements over a field-of-view (FOV with a horizontal radius of nearly 600 km for observations at an altitude of 250 km using a time resolution of 8 min. The instrument provides the ability to observe thermospheric spatial structure within a FOV which overlaps that of the EISCAT Svalbard radar and CUTLASS SuperDARN radars. Coordinating with these instruments provides an important opportunity for studying ion-neutral coupling. The all-sky image is divided into several sectors to provide a horizontal spatial resolution of between 100–300 km. This is a powerful extension in observational capability but requires careful calibration and data analysis, as described here. Two observation modes were used: a fixed and a scanning etalon gap. SCANDI results are corroborated using the Longyearbyen single look direction FPI, and ESR measurements of the ion temperatures. The data show thermospheric temperature gradients of a few Kelvins per kilometre, and a great deal of meso-scale variability on spatial scales of several tens of kilometres.

Non-invasive diagnosis in cerebral ischemia by means of magnetic resonance imaging and near-infrared spectroscopy

International Nuclear Information System (INIS)

Piepgras, A.; Gueckel, F.; Laemmler, B.; Weigel, R.; Schmiedek, P.

1994-01-01

We describe the non-invasive assessment of cerebrovascular reserve capacity by means of near-infrared spectroscopy (NIRS) and magnetic resonance imaging. Both methods are compared with transcranial Doppler sonography. There is a good correlation of the three methods in the changes in cerebral oxygen saturation and in blood velocity following acetazolamide stimulation of cerebral blood flow, except found in one patient with unilateral carotid artery occlusion. In this patient we found a decreased cerebrovascular reserve capacity, revealed by a magnetic resonance technique designed to quantify CBV and CBF. We postulate a raised oxygen extraction as raised oxygen extraction as the cause of his changes in oxygen saturation. (orig.) [de

Evaluation of valvular regurgitation by cine magnetic resonance imaging in patients with various cardiac diseases

International Nuclear Information System (INIS)

Kubota, Shuuhei; Nishimura, Tsunehiko

1990-01-01

In order to evaluate the clinical value and limitation of magnetic resonance imaging (MRI) for detection and quantification of valvular regurgitation, 98 patients with various cardiac diseases were studied by cine MRI and the results were compared with contrast angiography and doppler color-flow imaging. Cine MRI was carried out using FLASH (fast low angle shot) which employs TE of 10∼20 msec and TR of 30∼40 msec. 22 transverse tomograms per cardiac cycle with a slice thickness of 10 mm were obtained at the level of atrium and ventricle. The jet of valvular regurgitation was easily seen as a discrete are of low signal with cine MRI. Identification of the regurgitation and its severity were visually evaluated based on the relative size of the regurgitant jet from the incompetent valve orifice. Using contrast angiography as a gold standard, the sensitivity of cine MRI for detecting mitral regurgitation was 83% and was 94% for aortic regurgitation, with the specificity of 82% and 100%, respectively. For mitral requrgitation and aortic regurgitation, evaluation by cine MRI and severity agreed well with contrast angiography. By the comparative study with doppler color-flow imaging, relatively good agreement was found between the two methods in detection and quantitative evaluation of valvular regurgitation in any of four valves. Cine MRI was suggested to be useful for both the detection and semiquantification of valvular regurgitation in generally, but its clinical limitation at this point was also found because, 1)its images are not acquired in real times, as in contrast angiography or doppler color-flow imaging, but are compiled from the cumulative information from 128 heart beats, 2)the evaluation of regurgitation is made from only two-dimensional transverse tomograms. (author)

Differential magnetic force microscope imaging.

Science.gov (United States)

Wang, Ying; Wang, Zuobin; Liu, Jinyun; Hou, Liwei

2015-01-01

This paper presents a method for differential magnetic force microscope imaging based on a two-pass scanning procedure to extract differential magnetic forces and eliminate or significantly reduce background forces with reversed tip magnetization. In the work, the difference of two scanned images with reversed tip magnetization was used to express the local magnetic forces. The magnetic sample was first scanned with a low lift distance between the MFM tip and the sample surface, and the magnetization direction of the probe was then changed after the first scan to perform the second scan. The differential magnetic force image was obtained through the subtraction of the two images from the two scans. The theoretical and experimental results have shown that the proposed method for differential magnetic force microscope imaging is able to reduce the effect of background or environment interference forces, and offers an improved image contrast and signal to noise ratio (SNR). © Wiley Periodicals, Inc.

Power doppler 'blanching' after the application of transducer pressure

International Nuclear Information System (INIS)

Joshua, F.; Edmonds, J.; Lassere, M.; De Carle, R.; Rayment, M.; Bryant, C.; Shnier, R.

2005-01-01

The aim of this study was to determine if transducer pressure modifies power Doppler assessments of rheumatoid arthritis synovium at the metacarpophalangeal joints and metatarsophalangeal joints. Five rheumatoid arthritis patients of varying degrees of 'disease activity' and damage were assessed with power Doppler ultrasound scanning of the dominant hand second to fifth metacarpophalangeal joints. Two rheumatoid arthritis patients had their dominant foot first to fifth metatarsophalangeal joints assessed with power Doppler ultrasound. Ultrasonography was performed with a high frequency transducer (14 MHz) with a colour mode frequency of 10 Mhz, and a standard colour box and gain. In the joint that showed the highest power Doppler signal, an image was made. A further image was taken after transducer pressure was applied. In all patients, there was increased flow to at least one joint. After pressure was applied, power Doppler signal intensity markedly reduced in all images and in some there was no recordable power Doppler signal. Increased transducer pressure can result in a marked reduction or obliteration in power Doppler signal. This power Doppler 'blanching' shows the need for further studies to evaluate sources of error and standardization before power Doppler ultrasound becomes a routine measure of 'disease activity' in rheumatoid arthritis. Copyright (2005) Blackwell Science Pty Ltd

Explanation of the Inverse Doppler Effect Observed in Nonlinear Transmission Lines

International Nuclear Information System (INIS)

Kozyrev, Alexander B.; Weide, Daniel W. van der

2005-01-01

The theory of the inverse Doppler effect recently observed in magnetic nonlinear transmission lines is developed. We explain the crucial role of the backward spatial harmonic in the occurrence of an inverse Doppler effect and draw analogies of the magnetic nonlinear transmission line to the backward wave oscillator

Detection of Early Right Ventricular Dysfunction in Young Patients With Thalassemia Major Using Tissue Doppler Imaging

Science.gov (United States)

Bornaun, Helen; Dedeoglu, Reyhan; Oztarhan, Kazim; Dedeoglu, Savas; Erfidan, Erkan; Gundogdu, Muge; Aydogan, Gonul; Cengiz, Dicle

2016-01-01

Background Myocardial iron overload is the most common cause of mortality in patients with thalassemia major (TM), also known as beta-thalassemia. T2* cardiovascular magnetic resonance imaging (MRI) is the best way of monitoring cardiac iron, and new echocardiographic techniques can be used to assess cardiac function. Objectives The aim of this study was to assess the systolic and diastolic right ventricular (RV) function of patients with TM using tissue Doppler imaging (TDI) and to determine whether this echocardiographic technique is an adequate diagnostic tool for the screening and detection of subclinical cardiac dysfunction. Patients and Methods Eighty-four patients with TM were evaluated by conventional echocardiography and pulse-wave TDI. The data of the TM group (Group 1) were compared with that of 85 age- and sex-matched healthy controls (Group 2). Cardiovascular T2* MRI examinations were performed in 49 of the 85 patients. Results The patients with TM had significantly lower values for weight, height, body mass index, systolic arterial pressure, deceleration time, E’/A’, and ejection time (ET) than the controls. Group 1 also had significantly higher values for peak early diastolic velocity (E) over peak late diastolic velocity (A), peak early diastolic velocity of TDI (E’), peak late diastolic velocity of TDI (A’), E/E’, isovolumetric relaxation time, isovolumetric contraction time, and RV magnetic perfusion imaging (MPI) than Group 2. Conclusions RV diastolic dysfunction occurs before systolic deterioration in patients with TM and cannot be screened with conventional echocardiographic techniques. In routine practice, TDI measurements, MPI (for global function) and the E/E’ parameter (for diastolic function) can be used to screen and detect early RV dysfunction. PMID:27617076

Children's (Pediatric) Magnetic Resonance Imaging

Science.gov (United States)

... Physician Resources Professions Site Index A-Z Children’s (Pediatric) Magnetic Resonance Imaging Children’s magnetic resonance imaging (MRI) ... limitations of Children’s (Pediatric) MRI? What is Children’s (Pediatric) MRI? Magnetic resonance imaging (MRI) is a noninvasive ...

Magnetic Resonance Imaging (MRI) -- Head

Science.gov (United States)

... News Physician Resources Professions Site Index A-Z Magnetic Resonance Imaging (MRI) - Head Magnetic resonance imaging (MRI) of the head uses a powerful ... the Head? What is MRI of the Head? Magnetic resonance imaging (MRI) is a noninvasive medical test that ...

Children's (Pediatric) Magnetic Resonance Imaging

Medline Plus

Full Text Available ... Physician Resources Professions Site Index A-Z Children’s (Pediatric) Magnetic Resonance Imaging Children’s magnetic resonance imaging (MRI) ... limitations of Children’s (Pediatric) MRI? What is Children’s (Pediatric) MRI? Magnetic resonance imaging (MRI) is a noninvasive ...

Children's (Pediatric) Magnetic Resonance Imaging

Medline Plus

Full Text Available ... News Physician Resources Professions Site Index A-Z Children’s (Pediatric) Magnetic Resonance Imaging Children’s magnetic resonance imaging ( ... the limitations of Children’s (Pediatric) MRI? What is Children’s (Pediatric) MRI? Magnetic resonance imaging (MRI) is a ...

Imaging diagnosis and clinical findings of cerebral venous thrombosis in full-term neonates without brain damage: a ten-year review

International Nuclear Information System (INIS)

Monteiro, Alexandra Maria Vieira; Lima, Claudio Marcio Amaral de Oliveira; Ribeiro, Erica Barreiros; Lins, Maria Cristina; Miranda, Silvia; Miranda, Luis Eduardo

2010-01-01

Objective: to describe and compare imaging methods and clinical findings of cerebral venous thrombosis in four full-term neonates without brain damage, admitted to a neonatal intensive care unit. Materials and methods: ten-year review of four cases diagnosed with cerebral venous thrombosis by transfontanellar ultrasonography associated with Doppler fluxometry and confirmed by magnetic resonance imaging/magnetic resonance angiography in correlation with clinical findings and neurological progression. Results: ultrasonography presented normal results in 75% of cases and magnetic resonance imaging in 100%. Doppler fluxometry and magnetic resonance angiography were abnormal in 100% of cases. Hypoxia (100%) and early seizures (100%) were predominant among clinical findings with evoked potential changes in 50% of cases. In the assessment of the neuro development all the areas remained within normality parameters up to the conclusion of the present study. Conclusion: ultrasonography in association with Doppler can identify changes related to cerebral venous thrombosis and should be complemented with magnetic resonance imaging that is the gold standard for diagnosis in these cases. (author)

Cardiac magnetic resonance imaging

African Journals Online (AJOL)

2011-03-06

Mar 6, 2011 ... Cardiac magnetic resonance imaging. Cardiovascular magnetic resonance imaging is becoming a routine diagnostic technique. BRUCE s sPOTTiswOOdE, PhD. MRC/UCT Medical Imaging Research Unit, University of Cape Town, and Division of Radiology, Stellenbosch University. Bruce Spottiswoode ...

Magnetic Resonance Imaging (MRI) -- Head

Medline Plus

Full Text Available ... News Physician Resources Professions Site Index A-Z Magnetic Resonance Imaging (MRI) - Head Magnetic resonance imaging (MRI) of the head uses a powerful ... the Head? What is MRI of the Head? Magnetic resonance imaging (MRI) is a noninvasive medical test that ...

Correlation of transcranial Doppler ultrasonography with MRI and MRA in the evaluation of sickle cell disease patients with prior stroke

International Nuclear Information System (INIS)

Kogutt, M.S.; Goldwag, S.S.; Gupta, K.L.; Kaneko, K.; Humbert, J.R.

1994-01-01

We prospectively evaluated a group of patients with sickle cell disease and a clinical history of prior stroke, comparing transcranial Doppler sonography (TCD) to both magnetic resonance imaging (MRI) and magnetic resonance angiography (MRA) to determine its efficacy for the detection of flow abnormalities associated with prior cerebral infarction. Using MRI as the standard examination, there was 94 % sensitivity and 30 % specificity, and using MRA as the standard examination, there was 91 % sensitivity and 22 % specificity. We concur with other reports that the transcranial Doppler examination is a highly sensitive study. In our group of sickle cell disease patients with prior stroke, TCD reliably detected flow abnormalities that correlated to areas of prior cerebral infarction. (orig.)

Usefulness of Doppler echography for the diagnosis of traumatic carotid thrombosis

International Nuclear Information System (INIS)

Joaquín Castillo Duany.Santiago de Cuba (Cuba))" data-affiliation=" (Hospital Militar Joaquín Castillo Duany.Santiago de Cuba (Cuba))" >Rodríguez Montero, Enri; Joaquín Castillo Duany.Santiago de Cuba (Cuba))" data-affiliation=" (Hospital Militar Joaquín Castillo Duany.Santiago de Cuba (Cuba))" >González Méndez, Melvis; Joaquín Castillo Duany.Santiago de Cuba (Cuba))" data-affiliation=" (Hospital Militar Joaquín Castillo Duany.Santiago de Cuba (Cuba))" >González López, Ariel; Joaquín Castillo Duany.Santiago de Cuba (Cuba))" data-affiliation=" (Hospital Militar Joaquín Castillo Duany.Santiago de Cuba (Cuba))" >Campa, Belkis Ortega de la; Joaquín Castillo Duany.Santiago de Cuba (Cuba))" data-affiliation=" (Hospital Militar Joaquín Castillo Duany.Santiago de Cuba (Cuba))" >Germán Meliz, Jorge L.

2015-01-01

Carotid artery system traumas are rare and show high mortality rates. The case of right internal carotid artery thrombosis caused by a gunshot injury in the neck was presented in this report to show evidence of the usefulness of Doppler echography in the medical practice for the early diagnosis of these lesions in spite of the fact that literature highlights angiography, nuclear magnetic resonance and angioresonance as the imaging studies of choice. This case confirmed that carotid thrombosis due to trauma has low incidence but it can not be ignored in the cervical región traumas. For these reasons, the neurological complications stemming from artery occlusion are frequent and Doppler echography turned to be very useful for the early diagnosis of this illness in a patient. (author)

Systolic and Diastolic Function by Tissue Doppler Imaging Predicts Mortality in Patients with Atrial Fibrillation

DEFF Research Database (Denmark)

Dons, Maria; BieringSørensen, Tor; Jensen, Jan Skov

2015-01-01

AIM: Tissue Doppler Imaging (TDI) detects early signs of left ventricular dysfunction. The prognostic potential of TDI in patients with atrial fibrillation (AF) has, however, not yet been clarified. This study evaluates the prognostic value of TDI in patients with atrial fibrillation. METHODS...

Magnetic Resonance Imaging With Cochlear Implant Magnet in Place: Safety and Imaging Quality.

Science.gov (United States)

Carlson, Matthew L; Neff, Brian A; Link, Michael J; Lane, John I; Watson, Robert E; McGee, Kiaran P; Bernstein, Matt A; Driscoll, Colin L W

2015-07-01

To evaluate the safety and image quality of 1.5-T MRI in patients with cochlear implants and retained internal magnets. Retrospective case series from 2012 to 2014. Single tertiary academic referral center. All cochlear implant recipients undergoing 1.5-T MRI without internal magnet removal. MRI after tight headwrap application. Patient tolerance, complications, and characteristics of imaging artifact. Nineteen ears underwent a total of 34 MRI scans. Two patients did not tolerate imaging with the headwrap in place and required magnet removal before rescanning. One subject experienced two separate episodes of polarity reversal in the same device from physical realignment (i.e., flipping) of the internal magnet requiring surgical repositioning. Three patients were discovered to have canting of the internal magnet after imaging. In all three cases, the magnet could be reseated by applying gentle firm pressure to the scalp until the magnet "popped" back into place. These patients continue to use their device without difficulty and have not required surgical replacement. In patients receiving head MRI, the ipsilateral internal auditory canal and cerebellopontine angle could be visualized without difficulty in 94% of cases. There were no episodes of cochlear implant device failure or soft tissue complications. Under controlled conditions, 1.5-T MRI can be successfully performed in most patients without the need for cochlear implant magnet removal. In nearly all cases, imaging artifact does not impede evaluation of the ipsilateral skull base. Patients should be counseled regarding the risk of internal magnet movement that may occur in up to 15% of cases, even with tight headwrap application. If internal magnet polarity reversal occurs, a trial of reversing the external magnet can be considered. If canting or mild displacement of the internal magnet occurs, an attempt at reseating can be made by applying gentle firm pressure to the scalp over the internal magnet. If

Structure of a swirl-stabilized spray flame by imaging, laser Doppler velocimetry, and phase Doppler anemometry

Science.gov (United States)

Edwards, C. F.; Rudoff, R. C.

1991-01-01

Data are presented which describe the mean structure of a steady, swirl-stabilized, kerosene spray flame in the near-injector region of a research furnace. The data presented include ensemble-averaged results of schlieren, luminosity, and extinction imaging, measurement of the gas phase velocity field by laser Doppler velocimetry, and characterization of the condensed phase velocity by phase Doppler anemometry. The results of these studies define six key regions in the flame: the dense spray region; the rich, two-phase, fuel jet; the main air jet; the internal product recirculation zone; the external product recirculation zone; and the gaseous diffusion flame zone. The first five of these regions form a conical mixing layer which prepares the air and fuel for combustion. The air and fuel jets comprise the central portion of this mixing layer and are bounded on either side by the hot product gases of the internal and external recirculation zones. Entrainment of these product gases into the air/fuel streams provides the energy required to evaporate the fuel spray and initiate combustion. Intermittency of the internal recirculation and spray jet flows accounts for unexpected behavior observed in the aerodynamics of the two phases. The data reported herein are part of the database being accumulated on this spray flame for the purpose of detailed comparison with numerical modeling.

In-vivo imaging of blood flow dynamics using color Doppler optical coherence tomography

Science.gov (United States)

Yazdanfar, Siavash; Rollins, Andrew M.; Izatt, Joseph A.

2000-04-01

Noninvasive quantitation of blood flow in the retinal micro circulation may elucidate the progression and treatment of ocular disorders including diabetic retinopathy, age-related degeneration, and glaucoma. Color Doppler optical coherence tomography was recently introduced as a technique allowing simultaneous micron-scale resolution cross-sectional imaging of tissue micro structure and blood flow in the human retina. Here, time-resolved imaging of dynamics of blood flow profiles was performed to measure cardiac pulsatility within retinal vessels. Retinal pulsatility has been shown to decrease throughout the progression of diabetic retinopathy.

Ultrasonography with color Doppler and power Doppler in the diagnosis of periapical lesions

International Nuclear Information System (INIS)

Goel, Sumit; Nagendrareddy, Suma Gundareddy; Raju, Manthena Srinivasa; Krishnojirao, Dayashankara Rao Jingade; Rastogi, Rajul; Mohan, Ravi Prakash Sasankoti; Gupta, Swati

2011-01-01

To evaluate the efficacy of ultrasonography (USG) with color Doppler and power Doppler applications over conventional radiography in the diagnosis of periapical lesions. Thirty patients having inflammatory periapical lesions of the maxillary or mandibular anterior teeth and requiring endodontic surgery were selected for inclusion in this study. All patients consented to participate in the study. We used conventional periapical radiographs as well as USG with color Doppler and power Doppler for the diagnosis of these lesions. Their diagnostic performances were compared against histopathologic examination. All data were compared and statistically analyzed. USG examination with color Doppler and power Doppler identified 29 (19 cysts and 10 granulomas) of 30 periapical lesions accurately, with a sensitivity of 100% for cysts and 90.91% for granulomas and a specificity of 90.91% for cysts and 100% for granulomas. In comparison, conventional intraoral radiography identified only 21 lesions (sensitivity of 78.9% for cysts and 45.4% for granulomas and specificity of 45.4% for cysts and 78.9% for granulomas). There was definite correlation between the echotexture of the lesions and the histopathological features except in one case. USG imaging with color Doppler and power Doppler is superior to conventional intraoral radiographic methods for diagnosing the nature of periapical lesions in the anterior jaws. This study reveals the potential of USG examination in the study of other jaw lesions

Magnetic resonance imaging: effects of magnetic field strength

International Nuclear Information System (INIS)

Crooks, L.E.; Arakawa, M.; Hoenninger, J.; McCarten, B.; Watts, J.; Kaufman, L.

1984-01-01

Magnetic resonance images of the head, abdomen, and pelvis of normal adult men were obtained using varying magnetic field strength, and measurements of T1 and T2 relaxations and of signal-to-noise (SN) ratios were determined. For any one spin echo sequence, gray/white matter contrast decreases and muscle/fat contrast increases with field. SN levels rise rapidly up to 3.0 kgauss and then change more slowly, actually dropping for muscle. The optimum field for magnetic resonance imaging depends on tissue type, body part, and imaging sequence, so that it does not have a unique value. Magnetic resonance systems that operate in the 3.0-5.0 kgauss range achieve most or all of the gains that can be achieved by higher magnetic fields

NEW EVIDENCE OF MAGNETIC INTERACTIONS BETWEEN STARS FROM THREE-DIMENSIONAL DOPPLER TOMOGRAPHY OF ALGOL BINARIES: {beta} PER AND RS VUL

Energy Technology Data Exchange (ETDEWEB)

Richards, Mercedes T. [Department of Astronomy and Astrophysics, Pennsylvania State University, 525 Davey Laboratory, University Park, PA 16802 (United States); Agafonov, Michail I.; Sharova, Olga I., E-mail: mrichards@astro.psu.edu, E-mail: agfn@nirfi.sci-nnov.ru, E-mail: shol@nirfi.sci-nnov.ru [Radiophysical Research Institute (NIRFI), 25/12a, Bolshaya Pecherskaya St., Nizhny Novgorod 603950 (Russian Federation)

2012-11-20

Time-resolved H{alpha} spectra of magnetically active interacting binaries have been used to create three-dimensional (3D) Doppler tomograms by means of the Radioastronomical Approach. This is the first 3D reconstruction of {beta} Per, with RS Vul for comparison. These 3D tomograms have revealed evidence of the mass transfer process (gas stream, circumprimary emission, localized region, absorption zone), as well as loop prominences and coronal mass ejections (CMEs) in {beta} Per and RS Vul that could not be discovered from two-dimensional tomograms alone. The gas stream in both binaries may have been deflected beyond the central plane by the donor star's magnetic field. The stream was more elongated along the predicted trajectory in RS Vul than in {beta} Per, but not as pronounced as in U CrB (stream state). The loop prominence reached maximum V{sub z} velocities of {+-}155 km s{sup -1} in RS Vul compared to {+-}120 km s{sup -1} in {beta} Per, while the CME reached a maximum V{sub z} velocity of +150 km s{sup -1} in RS Vul and +100 km s{sup -1} in {beta} Per. The 3D tomograms show that the gas flows are not symmetric relative to the central plane and are not confined to that plane, a result confirmed by recent 15 GHz VLBI radio images of {beta} Per. Both the 3D H{alpha} tomography and the VLBI radio images support an earlier prediction of the superhump phenomenon in {beta} Per: that the gas between the stars is threaded with a magnetic field even though the hot B8V mass-gaining star is not known to have a magnetic field.

Cardiac time intervals by tissue Doppler imaging M-mode echocardiography

DEFF Research Database (Denmark)

Biering-Sørensen, Tor

2016-01-01

for myocardial myocytes to achieve an LV pressure equal to that of aorta increases, resulting in a prolongation of the isovolumic contraction time (IVCT). Furthermore, the ability of myocardial myocytes to maintain the LV pressure decreases, resulting in reduction in the ejection time (ET). As LV diastolic...... of whether the LV is suffering from impaired systolic or diastolic function. A novel method of evaluating the cardiac time intervals has recently evolved. Using tissue Doppler imaging (TDI) M-mode through the mitral valve (MV) to estimate the cardiac time intervals may be an improved method reflecting global...

Implementation and Comparison of Acoustic Travel-Time Measurement Procedures for the Helioseismic and Magnetic Imager Time-Distance Helioseismology Pipeline

Science.gov (United States)

Couvidat, S.; Zhao, J.; Birch, A. C.; Kosovichev, A. G.; Duvall, T. L., Jr.; Parchevsky, K.; Scherrer, P. H.

2009-01-01

The Helioseismic and Magnetic Imager (HMI) instrument on board the Solar Dynamics Observatory (SDO) satellite is designed to produce high-resolution Doppler velocity maps of oscillations at the solar surface with high temporal cadence. To take advantage of these high-quality oscillation data, a time-distance helioseismology pipeline has been implemented at the Joint Science Operations Center (JSOC) at Stanford University. The aim of this pipeline is to generate maps of acoustic travel times from oscillations on the solar surface, and to infer subsurface 3D flow velocities and sound-speed perturbations. The wave travel times are measured from cross covariances of the observed solar oscillation signals. For implementation into the pipeline we have investigated three different travel-time definitions developed in time-distance helioseismology: a Gabor wavelet fitting (Kosovichev and Duvall, 1997), a minimization relative to a reference cross-covariance function (Gizon and Birch, 2002), and a linearized version of the minimization method (Gizon and Birch, 2004). Using Doppler velocity data from the Michelson Doppler Imager (MDI) instrument on board SOHO, we tested and compared these definitions for the mean and difference travel-time perturbations measured from reciprocal signals. Although all three procedures return similar travel times in a quiet Sun region, the method of Gizon and Birch (2004) gives travel times that are significantly different from the others in a magnetic (active) region. Thus, for the pipeline implementation we chose the procedures of Kosovichev and Duvall (1997) and Gizon and Birch (2002). We investigated the relationships among these three travel-time definitions, their sensitivities to fitting parameters, and estimated the random errors they produce

Duplex sonography and magnetic resonance imaging in the clarification of nephrological complications after renal transplant

International Nuclear Information System (INIS)

Gueckel, C.; Krestin, G.P.; Wienand, P.

1989-01-01

A prospective study compared Duplex sonography and magnetic resonance imaging in evaluating renal transplant. Hundred and two Duplex sonographic and 24 MR examinations were performed and correlated with clinical course or biopsy. All normal renal allografts, 6 transplants with acute tubular necrosis and 2 cases of cyclosporin toxicity had normal Doppler waveforms, whereas 9 renal transplants with evidence of interstitial rejection by biopsy showed an obliteration or reversal of diastolic flow. MR imaging was less specific in identifying allograft rejection. There were false positive results in normal renal transplants, allografts with acute tubular necrosis and after rejection therapy. With regard to cost, accessibility and specificity, Duplex sonography is the method of choice for the evaluation of renal allografts. (orig.) [de

Prognostic value of tissue Doppler imaging for predicting ventricular arrhythmias and cardiovascular mortality in ischaemic cardiomyopathy

DEFF Research Database (Denmark)

Biering-Sørensen, Tor; Olsen, Flemming Javier; Storm, Katrine

2016-01-01

AIMS: Only 30% of patients receiving an implantable cardioverter defibrillator (ICD) for primary prevention receive appropriately therapy. We sought to investigate the value of tissue Doppler imaging (TDI) to predict ventricular tachycardia (VT), ventricular fibrillation (VF), and cardiovascular...

Magnetic resonance angiography in renal grafts. Comparison with color Doppler echography

International Nuclear Information System (INIS)

Yanagisawa, Takayoshi; Otsubo, Osamu; Nozaki, Harushige

1995-01-01

We studied relationship between magnetic resonance angiography (MRA) of renal graft and renal graft function in 14 renal transplantations (10 from living donors, 4 from cadaveric donors). MRA was performed on 0.3-T permanent magnet system (MRP 7000, HITACHI, JAPAN) using 2 dimensional time of flight technique (FOV: 350 mm 2 , RT: 60 msec, ET: 10 msec, FA: 90deg, Slice: volumes 60, thickness 4 mm, overlap 1 mm). As for parameters of renal graft function, we evaluated color doppler echography (CD) of transplanted renal artery, renal blood flow (RBF), velocity of interlobar artery (ILA) and serum creatinine level (S-Cr). CD, RBF and velocity of ILA were visualized and measured by duplex color doppler echosystem (EUB-565A, HITACHI, JAPAN). Depending on visualization of transplanted renal artery, MRA was graded into 3 groups (MA Grade 3: visualization of ILA, MA Grade 2: visualization of segmental artery and the first branch but no visualization of ILA, MA Grade 1: visualization of main renal artery only). Likewise, visualization of CD was graded into 3 groups (CD Grade 3: good visualization of arcuate artery (AA) and ILA, CD Grade 2: poor visualization of AA but good visualization of ILA, CD Grade 1: poor visualization of ILA). The MRA grading had a very significant correlation (r=0.79, p<0.001) with the CD grading. As for RBF and velocity of ILA, the RBF of MA Grade 3 group (n=8) was significantly (p<0.05) higher than the MA Grade 2 group (n=4) and the MA Grade 1 group (n=2), and the velocity of ILA of MA Grade 3 group was also higher than the above groups but not significantly. Furthermore, the S-Cr of MA Grade 3 was significantly (p<0.05) lower than the others. These results showed that MRA of renal graft had a qualitative index of renal graft function. (author)

Power Doppler ultrasonography and synovitis: correlating ultrasound imaging with histopathological findings and evaluating the performance of ultrasound equipments.

Science.gov (United States)

Koski, J M; Saarakkala, S; Helle, M; Hakulinen, U; Heikkinen, J O; Hermunen, H

2006-12-01

To examine the validity of power Doppler ultrasound imaging to identify synovitis, using histopathology as gold standard, and to assess the performance of ultrasound equipments. 44 synovial sites in small and large joints, bursae and tendon sheaths were depicted with ultrasound. A synovial biopsy was performed on the site depicted and a synovial sample was taken for histopathological evaluation. The performance of three ultrasound devices was tested using flow phantoms. A positive Doppler signal was detected in 29 of 35 (83%) of the patients with active histological inflammation. In eight additional samples, histological examination showed other pathological synovial findings and a Doppler signal was detected in five of them. No significant correlation was found between the amount of Doppler signal and histological synovitis score (r = 0.239, p = NS). The amount of subsynovial infiltration of polymorphonuclear leucocytes and surface fibrin correlated significantly with the amount of power Doppler signal: r = 0.397 (pultrasound devices differed in showing the smallest detectable flow. A negative Doppler signal does not exclude the possibility of synovitis. A positive Doppler signal in the synovium is an indicator of an active synovial inflammation in patients. A Doppler signal does not correlate with the extent of the inflammation and it can also be seen in other synovial reactions. It is important that the quality measurements of ultrasound devices are reported, because the results should be evaluated against the quality of the device used.

A superconducting magnet for whole-body magnetic-resonance imaging

International Nuclear Information System (INIS)

Kan, Hisao; Watanabe, Tsugio; Takechi, Moriaki; Ogino, Osamu; Yamada, Tadatoshi

1986-01-01

Magnetic-resonance imaging is a promising new clinical diagnosis system that employs magnetic resonance to generate cross-sectional images of the object under examination. A large magnet plays a critical role in this system-it must supply a high-strength magnetic field that meets rigid standards of space and time uniformity. Mitsubishi Electric has developed a superconducting magnet that not only offers excellent magnetic characteristics but also features reduced helium consumption and a horizontal service port, and permits direct mounting of a magnetic shield. (author)

MEMS-based handheld fourier domain Doppler optical coherence tomography for intraoperative microvascular anastomosis imaging.

Directory of Open Access Journals (Sweden)

Yong Huang

Full Text Available To demonstrate the feasibility of a miniature handheld optical coherence tomography (OCT imager for real time intraoperative vascular patency evaluation in the setting of super-microsurgical vessel anastomosis.A novel handheld imager Fourier domain Doppler optical coherence tomography based on a 1.3-µm central wavelength swept source for extravascular imaging was developed. The imager was minimized through the adoption of a 2.4-mm diameter microelectromechanical systems (MEMS scanning mirror, additionally a 12.7-mm diameter lens system was designed and combined with the MEMS mirror to achieve a small form factor that optimize functionality as a handheld extravascular OCT imager. To evaluate in-vivo applicability, super-microsurgical vessel anastomosis was performed in a mouse femoral vessel cut and repair model employing conventional interrupted suture technique as well as a novel non-suture cuff technique. Vascular anastomosis patency after clinically successful repair was evaluated using the novel handheld OCT imager.With an adjustable lateral image field of view up to 1.5 mm by 1.5 mm, high-resolution simultaneous structural and flow imaging of the blood vessels were successfully acquired for BALB/C mouse after orthotopic hind limb transplantation using a non-suture cuff technique and BALB/C mouse after femoral artery anastomosis using a suture technique. We experimentally quantify the axial and lateral resolution of the OCT to be 12.6 µm in air and 17.5 µm respectively. The OCT has a sensitivity of 84 dB and sensitivity roll-off of 5.7 dB/mm over an imaging range of 5 mm. Imaging with a frame rate of 36 Hz for an image size of 1000(lateral×512(axial pixels using a 50,000 A-lines per second swept source was achieved. Quantitative vessel lumen patency, lumen narrowing and thrombosis analysis were performed based on acquired structure and Doppler images.A miniature handheld OCT imager that can be used for intraoperative evaluation of

Detection of magnetic nanoparticles in tissue using magneto-motive ultrasound

International Nuclear Information System (INIS)

Oh, Junghwan; Feldman, Marc D; Kim, Jeehyun; Condit, Chris; Emelianov, Stanislav; Milner, Thomas E

2006-01-01

The purpose of this study was to demonstrate the magneto-motive ultrasonic detection of superparamagnetic iron oxide (SPIO) nanoparticles as a marker of macrophage recruitment in tissue. The capability of ultrasound to detect SPIO nanoparticles (core diameter ∼20 nm) taken up by murine liver macrophages was investigated. Eight mice were sacrificed two days after the intravenous administration of four SPIO doses (1.5, 1.0, 0.5, and 0.1 mmol Fe/kg body weight). In the iron-laden livers, ultrasound Doppler measurements showed a frequency shift in response to an applied time-varying magnetic field. M-mode scan and colour power Doppler images of the iron-laden livers also demonstrated nanoparticle movement under focused magnetic field excitation. In the livers of two saline injected control mice, no movement was observed using any ultrasound imaging modes. The results of our experiments indicate that ultrasound imaging of magneto-motive excitation is a candidate imaging modality to identify tissue-based macrophages containing SPIO nanoparticles

Total average diastolic longitudinal displacement by colour tissue doppler imaging as an assessment of diastolic function

DEFF Research Database (Denmark)

de Knegt, Martina Chantal; Biering-Sørensen, Tor; Søgaard, Peter

2016-01-01

BACKGROUND: The current method for a non-invasive assessment of diastolic dysfunction is complex with the use of algorithms of many different echocardiographic parameters. Total average diastolic longitudinal displacement (LD), determined by colour tissue Doppler imaging (TDI) via the measurement...

Children's (Pediatric) Magnetic Resonance Imaging

Medline Plus

Full Text Available ... Resources Professions Site Index A-Z Children’s (Pediatric) Magnetic Resonance Imaging Children’s magnetic resonance imaging (MRI) uses ... identify and accurately characterize diseases than other imaging methods. This detail makes MRI an invaluable tool in ...

Ultrasonography with color Doppler and power Doppler in the diagnosis of periapical lesions

Science.gov (United States)

Goel, Sumit; Nagendrareddy, Suma Gundareddy; Raju, Manthena Srinivasa; Krishnojirao, Dayashankara Rao Jingade; Rastogi, Rajul; Mohan, Ravi Prakash Sasankoti; Gupta, Swati

2011-01-01

Aim: To evaluate the efficacy of ultrasonography (USG) with color Doppler and power Doppler applications over conventional radiography in the diagnosis of periapical lesions. Materials and Methods: Thirty patients having inflammatory periapical lesions of the maxillary or mandibular anterior teeth and requiring endodontic surgery were selected for inclusion in this study. All patients consented to participate in the study. We used conventional periapical radiographs as well as USG with color Doppler and power Doppler for the diagnosis of these lesions. Their diagnostic performances were compared against histopathologic examination. All data were compared and statistically analyzed. Results: USG examination with color Doppler and power Doppler identified 29 (19 cysts and 10 granulomas) of 30 periapical lesions accurately, with a sensitivity of 100% for cysts and 90.91% for granulomas and a specificity of 90.91% for cysts and 100% for granulomas. In comparison, conventional intraoral radiography identified only 21 lesions (sensitivity of 78.9% for cysts and 45.4% for granulomas and specificity of 45.4% for cysts and 78.9% for granulomas). There was definite correlation between the echotexture of the lesions and the histopathological features except in one case. Conclusions: USG imaging with color Doppler and power Doppler is superior to conventional intraoral radiographic methods for diagnosing the nature of periapical lesions in the anterior jaws. This study reveals the potential of USG examination in the study of other jaw lesions. PMID:22223940

Ultrasonography with color Doppler and power Doppler in the diagnosis of periapical lesions

Directory of Open Access Journals (Sweden)

Sumit Goel

2011-01-01

Full Text Available Aim: To evaluate the efficacy of ultrasonography (USG with color Doppler and power Doppler applications over conventional radiography in the diagnosis of periapical lesions. Materials and Methods: Thirty patients having inflammatory periapical lesions of the maxillary or mandibular anterior teeth and requiring endodontic surgery were selected for inclusion in this study. All patients consented to participate in the study. We used conventional periapical radiographs as well as USG with color Doppler and power Doppler for the diagnosis of these lesions. Their diagnostic performances were compared against histopathologic examination. All data were compared and statistically analyzed. Results: USG examination with color Doppler and power Doppler identified 29 (19 cysts and 10 granulomas of 30 periapical lesions accurately, with a sensitivity of 100% for cysts and 90.91% for granulomas and a specificity of 90.91% for cysts and 100% for granulomas. In comparison, conventional intraoral radiography identified only 21 lesions (sensitivity of 78.9% for cysts and 45.4% for granulomas and specificity of 45.4% for cysts and 78.9% for granulomas. There was definite correlation between the echotexture of the lesions and the histopathological features except in one case. Conclusions: USG imaging with color Doppler and power Doppler is superior to conventional intraoral radiographic methods for diagnosing the nature of periapical lesions in the anterior jaws. This study reveals the potential of USG examination in the study of other jaw lesions.

Microvascular anastomosis in rodent model evaluated by Fourier domain Doppler optical coherence tomography

Science.gov (United States)

Huang, Yong; Tong, Dedi; Zhu, Shan; Wu, Lehao; Ibrahim, Zuhaib; Lee, WP Andrew; Brandacher, Gerald; Kang, Jin U.

2014-03-01

Vascular and microvascular anastomosis are critical components of reconstructive microsurgery, vascular surgery and transplant surgery. Imaging modality that provides immediate, real-time in-depth view and 3D structure and flow information of the surgical site can be a great valuable tool for the surgeon to evaluate surgical outcome following both conventional and innovative anastomosis techniques, thus potentially increase the surgical success rate. Microvascular anastomosis for vessels with outer diameter smaller than 1.0 mm is extremely challenging and effective evaluation of the outcome is very difficult if not impossible using computed tomography (CT) angiograms, magnetic resonance (MR) angiograms and ultrasound Doppler. Optical coherence tomography (OCT) is a non-invasive high-resolution (micron level), high-speed, 3D imaging modality that has been adopted widely in biomedical and clinical applications. Phaseresolved Doppler OCT that explores the phase information of OCT signals has been shown to be capable of characterizing dynamic blood flow clinically. In this work, we explore the capability of Fourier domain Doppler OCT as an evaluation tool to detect commonly encountered post-operative complications that will cause surgical failure and to confirm positive result with surgeon's observation. Both suture and cuff based techniques were evaluated on the femoral artery and vein in the rodent model.

Magnetic resonance imaging

International Nuclear Information System (INIS)

Robertson, Angus

1990-01-01

An assessment is made of the clinical benefits of expensive diagnostic technology, such as the magnetic resonance imaging. It is concluded that to most radiologists, magnetic resonance imaging has a definite place in the diagnostic scenario, especially for demonstrating central nervous system lesions in multiple sclerosis. While it is recognized that medical and financial resources are limited, it is emphasised that the cost to society must be balanced against the patient benefit. 17 refs

Temporal enhancement of two-dimensional color doppler echocardiography

Science.gov (United States)

Terentjev, Alexey B.; Settlemier, Scott H.; Perrin, Douglas P.; del Nido, Pedro J.; Shturts, Igor V.; Vasilyev, Nikolay V.

2016-03-01

Two-dimensional color Doppler echocardiography is widely used for assessing blood flow inside the heart and blood vessels. Currently, frame acquisition time for this method varies from tens to hundreds of milliseconds, depending on Doppler sector parameters. This leads to low frame rates of resulting video sequences equal to tens of Hz, which is insufficient for some diagnostic purposes, especially in pediatrics. In this paper, we present a new approach for reconstruction of 2D color Doppler cardiac images, which results in the frame rate being increased to hundreds of Hz. This approach relies on a modified method of frame reordering originally applied to real-time 3D echocardiography. There are no previous publications describing application of this method to 2D Color Doppler data. The approach has been tested on several in-vivo cardiac 2D color Doppler datasets with approximate duration of 30 sec and native frame rate of 15 Hz. The resulting image sequences had equivalent frame rates to 500Hz.

Quantification of colour Doppler activity in the wrist in patients with rheumatoid arthritis - the reliability of different methods for image selection and evaluation

DEFF Research Database (Denmark)

Ellegaard, K.; Torp-Pedersen, S.; Lund, H.

2008-01-01

measurements in the wrist of patients with rheumatoid arthritis (RA) using different selection and quantification methods. Materials and Methods: 14 patients with RA had their wrist scanned twice by the same investigator with an interval of 30 Minutes, The images for analysis were selected either......Purpose: The amount Of colour Doppler activity in the inflamed synovium is used to quantity inflammatory activity. The measurements may vary due to image selection, quantification method, and point in cardiac cycle. This study investigated the test-retest reliability Of ultrasound colour Doppler...... was obtained when the images were selected guided by colour Doppler and the Subsequent quantification was (done in an area defined by anatomical Structures. With this method, the intra-class coefficient ICC (2.1) was 0.95 and the within-subject SD (SW) was 0.017, indicating good reliability. In contrast, poor...

Wide angle Michelson Doppler imaging interferometer. [measuring atmospheric emissions

Science.gov (United States)

Shepherd, G. G.

1980-01-01

The optical system, stepping control, phase and modulation depth, array detector, and directions sensor are described for a specialized type of Michelson interferometer which works at sufficiently high resolution to measure the line widths and Doppler shifts of naturally occurring atmospheric emissions. With its imaging capability, the instrument can potentially supply this data independently for each element of the 100 x 100 detector array. The experiment seeks: (1) to obtain vertical profiles of atmospheric winds and temperatures as functions of latitude by observing near the limb; (2) to acquire exploratory wind and temperature data on smaller scale structures in airglow irregularities and in auroral forms; and (3) to collaborate with other Spacelab experiments, such as barium cloud releases, in providing wind and temperature data.

Complex regression Doppler optical coherence tomography

Science.gov (United States)

Elahi, Sahar; Gu, Shi; Thrane, Lars; Rollins, Andrew M.; Jenkins, Michael W.

2018-04-01

We introduce a new method to measure Doppler shifts more accurately and extend the dynamic range of Doppler optical coherence tomography (OCT). The two-point estimate of the conventional Doppler method is replaced with a regression that is applied to high-density B-scans in polar coordinates. We built a high-speed OCT system using a 1.68-MHz Fourier domain mode locked laser to acquire high-density B-scans (16,000 A-lines) at high enough frame rates (˜100 fps) to accurately capture the dynamics of the beating embryonic heart. Flow phantom experiments confirm that the complex regression lowers the minimum detectable velocity from 12.25 mm / s to 374 μm / s, whereas the maximum velocity of 400 mm / s is measured without phase wrapping. Complex regression Doppler OCT also demonstrates higher accuracy and precision compared with the conventional method, particularly when signal-to-noise ratio is low. The extended dynamic range allows monitoring of blood flow over several stages of development in embryos without adjusting the imaging parameters. In addition, applying complex averaging recovers hidden features in structural images.

Imaging of plantar fascia disorders: findings on plain radiography, ultrasound and magnetic resonance imaging.

Science.gov (United States)

Draghi, Ferdinando; Gitto, Salvatore; Bortolotto, Chandra; Draghi, Anna Guja; Ori Belometti, Gioia

2017-02-01

Plantar fascia (PF) disorders commonly cause heel pain and disability in the general population. Imaging is often required to confirm diagnosis. This review article aims to provide simple and systematic guidelines for imaging assessment of PF disease, focussing on key findings detectable on plain radiography, ultrasound and magnetic resonance imaging (MRI). Sonographic characteristics of plantar fasciitis include PF thickening, loss of fibrillar structure, perifascial collections, calcifications and hyperaemia on Doppler imaging. Thickening and signal changes in the PF as well as oedema of adjacent soft tissues and bone marrow can be assessed on MRI. Radiographic findings of plantar fasciitis include PF thickening, cortical irregularities and abnormalities in the fat pad located deep below the PF. Plantar fibromatosis appears as well-demarcated, nodular thickenings that are iso-hypoechoic on ultrasound and show low-signal intensity on MRI. PF tears present with partial or complete fibre interruption on both ultrasound and MRI. Imaging description of further PF disorders, including xanthoma, diabetic fascial disease, foreign-body reactions and plantar infections, is detailed in the main text. Ultrasound and MRI should be considered as first- and second-line modalities for assessment of PF disorders, respectively. Indirect findings of PF disease can be ruled out on plain radiography. Teaching Points • PF disorders commonly cause heel pain and disability in the general population.• Imaging is often required to confirm diagnosis or reveal concomitant injuries.• Ultrasound and MRI respectively represent the first- and second-line modalities for diagnosis.• Indirect findings of PF disease can be ruled out on plain radiography.

[Development of RF coil of permanent magnet mini-magnetic resonance imager and mouse imaging experiments].

Science.gov (United States)

Hou, Shulian; Xie, Huantong; Chen, Wei; Wang, Guangxin; Zhao, Qiang; Li, Shiyu

2014-10-01

In the development of radio frequency (RF) coils for better quality of the mini-type permanent magnetic resonance imager for using in the small animal imaging, the solenoid RF coil has a special advantage for permanent magnetic system based on analyses of various types.of RF coils. However, it is not satisfied for imaging if the RF coils are directly used. By theoretical analyses of the magnetic field properties produced from the solenoid coil, the research direction was determined by careful studies to raise further the uniformity of the magnetic field coil, receiving coil sensitivity for signals and signal-to-noise ratio (SNR). The method had certain advantages and avoided some shortcomings of the other different coil types, such as, birdcage coil, saddle shaped coil and phased array coil by using the alloy materials (from our own patent). The RF coils were designed, developed and made for keeled applicable to permanent magnet-type magnetic resonance imager, multi-coil combination-type, single-channel overall RF receiving coil, and applied for a patent. Mounted on three instruments (25 mm aperture, with main magnetic field strength of 0.5 T or 1.5 T, and 50 mm aperture, with main magnetic field strength of 0.48 T), we performed experiments with mice, rats, and nude mice bearing tumors. The experimental results indicated that the RF receiving coil was fully applicable to the permanent magnet-type imaging system.

Magnetic resonance imaging - first human images in Australia

International Nuclear Information System (INIS)

Baddeley, H.; Doddrell, D.M.; Brooks, W.M.; Field, J.; Irving, M.; Williams, J.E.

1986-01-01

The use of magnetic resonance imaging, in the demonstration of internal human anatomy and in the diagnosis of disease, has the major advantages that the technique is non-invasive, does not require the use of ionizing radiation and that it can demonstrate neurological and cardiovascular lesions that cannot be diagnosed easily by other imaging methods. The first magnetic resonance images of humans were obtained in Australia in October 1985 on the research instrument of the Queensland Medical Magnetic Resonance Research Centre, which is based at the Mater Hospital in Brisbane

Magnetic imaging and its applications to materials

CERN Document Server

De Graef, Marc

2000-01-01

Volume 36 provides an extensive introduction to magnetic imaging,including theory and practice, utilizing a wide range of magnetic sensitive imaging methods. It also illustrates the applications of these modern experimental techniques together with imaging calculations to today's advanced magnetic materials. This book is geared towards the upper-level undergraduate students and entry-level graduate students majoring in physics or materials science who are interested in magnetic structure and magnetic imaging. Researchers involved in studying magnetic materials should alsofind the book usef

Magnetic Resonance Imaging of Surgical Implants Made from Weak Magnetic Materials

Science.gov (United States)

Gogola, D.; Krafčík, A.; Štrbák, O.; Frollo, I.

2013-08-01

Materials with high magnetic susceptibility cause local inhomogeneities in the main field of the magnetic resonance (MR) tomograph. These inhomogeneities lead to loss of phase coherence, and thus to a rapid loss of signal in the image. In our research we investigated inhomogeneous field of magnetic implants such as magnetic fibers, designed for inner suture during surgery. The magnetic field inhomogeneities were studied at low magnetic planar phantom, which was made from four thin strips of magnetic tape, arranged grid-wise. We optimized the properties of imaging sequences with the aim to find the best setup for magnetic fiber visualization. These fibers can be potentially exploited in surgery for internal stitches. Stitches can be visualized by the magnetic resonance imaging (MRI) method after surgery. This study shows that the imaging of magnetic implants is possible by using the low field MRI systems, without the use of complicated post processing techniques (e.g., IDEAL).

Magnetic nanoparticles in magnetic resonance imaging and diagnostics.

Science.gov (United States)

Rümenapp, Christine; Gleich, Bernhard; Haase, Axel

2012-05-01

Magnetic nanoparticles are useful as contrast agents for magnetic resonance imaging (MRI). Paramagnetic contrast agents have been used for a long time, but more recently superparamagnetic iron oxide nanoparticles (SPIOs) have been discovered to influence MRI contrast as well. In contrast to paramagnetic contrast agents, SPIOs can be functionalized and size-tailored in order to adapt to various kinds of soft tissues. Although both types of contrast agents have a inducible magnetization, their mechanisms of influence on spin-spin and spin-lattice relaxation of protons are different. A special emphasis on the basic magnetism of nanoparticles and their structures as well as on the principle of nuclear magnetic resonance is made. Examples of different contrast-enhanced magnetic resonance images are given. The potential use of magnetic nanoparticles as diagnostic tracers is explored. Additionally, SPIOs can be used in diagnostic magnetic resonance, since the spin relaxation time of water protons differs, whether magnetic nanoparticles are bound to a target or not.

Magnetic Resonance Imaging (MRI) Safety

Science.gov (United States)

... News Physician Resources Professions Site Index A-Z Magnetic Resonance Imaging (MRI) Safety What is MRI and how ... What is MRI and how does it work? Magnetic resonance imaging, or MRI, is a way of obtaining ...

Evaluation of Portal Venous Velocity with Doppler Ultrasound in Patients with Nonalcoholic Fatty Liver Disease

Energy Technology Data Exchange (ETDEWEB)

Ulusan, Serife; Yakar, Tolga; Koc, Zafer [Baskent University Faculty of Medicine, Adana (Turkmenistan)

2011-08-15

We examined the relationship between portal venous velocity and hepatic-abdominal fat in patients with nonalcoholic fatty liver disease (NAFLD), using spectral Doppler ultrasonography (US) and magnetic resonance imaging (MRI). In this prospective study, 35 patients with NAFLD and 29 normal healthy adults (control group) underwent portal Doppler US. The severity of hepatic steatosis in patients with NAFLD was assessed by MRI through chemical shift imaging, using a modification of the Dixon method. Abdominal (intra-abdominal and subcutaneous) fat was measured by MRI. The difference in portal venous velocity between the patients with NAFLD and the control group was significant (p < 0.0001). There was no correlation between the degree of abdominal or hepatic fat and portal venous velocity (p > 0.05). There were strong correlations between the hepatic fat fraction and subcutaneous adiposity (p < 0.0001), intraperitoneal fat accumulation (p 0.017), and retroperitoneal fat accumulation (p < 0.0001). Our findings suggest that patients with NAFLD have lower portal venous velocities than normal healthy subjects.

Laser Doppler imaging as a tool in the burn wound treatment protocol

OpenAIRE

Venclauskiene, Algirda; Basevicius, Algidas; Zacharevskij, Ernest; Vaicekauskas, Vytautas; Rimdeika, Rytis; Lukosevicius, Saulius

2014-01-01

Introduction The main treatment of burns is early excision of injured tissues. Aim To compare two different methods of examination of burned patients: clinical burn depth examination (CDE) and laser Doppler imaging (LDI). Material and methods A prospective randomized study of 57 burn patients treated in 2009–2011 was carried out. The burned patients were randomized into a CDE group and an LDI group. The CDE and LDI scan were performed 72 h after injury, with the second and third CDE and LDI s...

Magnetic Resonance Imaging (MRI) -- Head

Medline Plus

Full Text Available ... by the interpreting radiologist. Frequently, the differentiation of abnormal (diseased) tissue from normal tissues is better with ... Tumor Treatment Magnetic Resonance Imaging (MRI) Safety Alzheimer's Disease Head Injury Brain Tumors Images related to Magnetic ...

Principles of magnetic resonance imaging

International Nuclear Information System (INIS)

Mlynarik, V.; Tkac, I.; Srbecky, M.

1995-01-01

The aim of this review is to describe and explain the basic principles of magnetic resonance imaging. The first part of the text is devoted to the phenomenon of magnetic resonance (the interaction of RF magnetic field with the set of magnetic moments in the homogeneous magnetic field) and to relaxation processes. Then, the creation of MR image is described (slice selection, phase and frequency encoding of spatial information). The basic and the most frequently used techniques are explained (spin echo, gradient echo). The way the repetition and echo times influence the image quality and contrast (T1 or T2 weighing) is described. The part with the technical description of the MR equipment is included in the review. The MR imagination examination are compared with X-ray computer tomography technique

Magnetic Resonance Imaging. Chapter 15

Energy Technology Data Exchange (ETDEWEB)

Leach, M. O. [The Institute of Cancer Research and The Royal Marsden Hospital, London (United Kingdom)

2014-09-15

In Chapter 14, the principles of nuclear magnetic resonance were presented, along with an introduction to image forming processes. In this chapter, magnetic resonance imaging (MRI) will be reviewed, beginning with the hardware needed and its impact on image quality. The acquisition processes and image reconstruction will be discussed, as well as the artefacts that are possible, with discussion of the important area of safety and bioeffects completing the chapter.

Musculoskeletal colour/power Doppler in sports medicine: image parameters, artefacts, image interpretation and therapy

DEFF Research Database (Denmark)

Boesen, M I; Boesen, Mikael; Kønig, Merete Juhl

2010-01-01

This review article discusses the aspects of sports medicine where musculoskeletal Doppler ultrasound has valuable contribution in diagnosis and/or treatment of some of the typical musculoskeletal sports injuries. Also, conditions where the Doppler ultrasound has no value are discussed. Some...

Musculoskeletal colour/power Doppler in sports medicine: image parameters, artefacts, image interpretation and therapy

DEFF Research Database (Denmark)

Boesen, M I; Boesen, Mikael; Kønig, Merete Juhl

2011-01-01

This review article discusses the aspects of sports medicine where musculoskeletal Doppler ultrasound has valuable contribution in diagnosis and/or treatment of some of the typical musculoskeletal sports injuries. Also, conditions where the Doppler ultrasound has no value are discussed. Some...

Magnetic Resonance Imaging of Stroke

NARCIS (Netherlands)

Bouts, Mark. J. R. J.; Wu, O.; Dijkhuizen, R. M.

2017-01-01

Magnetic resonance imaging (MRI) provides a powerful (neuro)imaging modality for the diagnosis and outcome prediction after (acute) stroke. Since MRI allows noninvasive, longitudinal, and three-dimensional assessment of vessel occlusion (with magnetic resonance angiography (MRA)), tissue injury

Preliminary measurements of the edge magnetic field pitch from 2-D Doppler backscattering in MAST and NSTX-U

OpenAIRE

Vann, Roderick G L; Brunner, Jakob; Ellis, R; Taylor, Gary; Thomas, David Allden

2016-01-01

The Synthetic Aperture Microwave Imaging (SAMI) system is a novel diagnostic consisting of an array of 8 independently-phased antennas. At any one time, SAMI operates at one of 16 frequencies in the range 10-34.5GHz. The imaging beam is steered in software post-shot to create a picture of the entire emission surface. In SAMI’s active probing mode of operation, the plasma edge is illuminated with a monochromatic source and SAMI reconstructs an image of the Doppler back-scattered (DBS) signal. ...

Moving Target Detection With Compact Laser Doppler Radar

Science.gov (United States)

Sepp, G.; Breining, A.; Eisfeld, W.; Knopp, R.; Lill, E.; Wagner, D.

1989-12-01

This paper describes an experimental integrated optronic system for detection and tracking of moving objects. The system is based on a CO2 waveguide laser Doppler ra-dar with homodyne receiver and galvanometer mirror beam scanner. A "hot spot" seeker consisting of a thermal imager with image processor transmits the coordinates of IR-emitting, i.e. potentially powered, objects to the laser radar scanner. The scanner addresses these "hot" locations operating in a large field-of-view (FOV) random ac-cess mode. Hot spots exhibiting a Doppler shifted laser signal are indicated in the thermal image by velocity-to-colour encoded markers. After switching to a small FOV scanning mode, the laser Doppler radar is used to track fast moving objects. Labora-tory and field experiments with moving objects including rotating discs, automobiles and missiles are described.

The role of magnetic resonance imaging and ultrasound in patients with adnexal masses.

Science.gov (United States)

Sohaib, S A; Mills, T D; Sahdev, A; Webb, J A W; Vantrappen, P O; Jacobs, I J; Reznek, R H

2005-03-01

To evaluate the accuracy of ultrasonography (US) and magnetic resonance imaging (MRI) in characterizing adnexal masses, and to determine which patients may benefit from MRI. We prospectively studied 72 women (mean age 53 years, range 19 to 86 years) with clinically suspected adnexal masses. A single experienced sonographer performed transabdominal and transvaginal greyscale spectral and colour Doppler examinations. MRI was carried out on a 1.5T system using T1, T2 and fat-suppressed T1-weighted sequences before and after intravenous injection of gadolinium. The adnexal masses were categorized as benign or malignant without knowledge of clinical details, according to the imaging features which were compared with the surgical and pathological findings. For characterizing lesions as malignant, the sensitivity, specificity and accuracy of MRI were 96.6%, 83.7% and 88.9%, respectively, and of US were 100%, 39.5% and 63.9%, respectively. MRI was more specific (pbenign and 28 (39%) cases with malignant masses. MRI correctly diagnosed 19 (26%) cases with benign lesion(s), which on US were thought to be malignant. The age, menopausal status and CA-125 levels in these women made benign disease likely, but US features were suggestive of malignancy (large masses and solid-cystic lesions with nodules). MRI is more specific and accurate than US and Doppler assessment for characterizing adnexal masses. Women who clinically have a relatively low risk of malignancy but who have complex sonographic features may benefit from MRI.

Children's (Pediatric) Magnetic Resonance Imaging

Medline Plus

Full Text Available ... Resources Professions Site Index A-Z Children’s (Pediatric) Magnetic Resonance Imaging Children’s magnetic resonance imaging (MRI) uses a powerful ... for an MRI exam contains a metal called gadolinium . Gadolinium can be used in patients with iodine ...

Diagnostic imaging of psoriatic arthritis. Part II: magnetic resonance imaging and ultrasonography

Directory of Open Access Journals (Sweden)

Iwona Sudoł-Szopińska

2016-06-01

Full Text Available Plain radiography reveals specific, yet late changes of advanced psoriatic arthritis. Early inflammatory changes are seen both on magnetic resonance imaging and ultrasound within peripheral joints (arthritis, synovitis, tendons sheaths (tenosynovitis, tendovaginitis and entheses (enthesitis, enthesopathy. In addition, magnetic resonance imaging enables the assessment of inflammatory features in the sacroiliac joints (sacroiliitis, and the spine (spondylitis. In this article, we review current opinions on the diagnostics of some selective, and distinctive features of psoriatic arthritis concerning magnetic resonance imaging and ultrasound and present some hypotheses on psoriatic arthritis etiopathogenesis, which have been studied with the use of magnetic resonance imaging. The following elements of the psoriatic arthritis are discussed: enthesitis, extracapsular inflammation, dactylitis, distal interphalangeal joint and nail disease, and the ability of magnetic resonance imaging to differentiate undifferentiated arthritis, the value of whole-body magnetic resonance imaging and dynamic contrast-enhanced magnetic resonance imaging.

The application of color Doppler flow imaging in the diagnosis and therapeutic effect evaluation of erectile dysfunction

Directory of Open Access Journals (Sweden)

Xu-Jun Xuan

2016-01-01

Full Text Available We aim to investigate the correlations between hemodynamic parameters, penile rigidity grading, and the therapeutic effects of phosphodiesterase type 5 inhibitors using color Doppler flow imaging after intracavernosal injection in patients with erectile dysfunction. This study involved 164 patients. After intracavernosal injection with a mixture of papaverine (60 mg, prostaglandin E 1 (10 mg, and lidocaine (2%, 0.5-1 ml, the penile vessels were assessed using color Doppler flow imaging. Penile rigidity was classified based on the Erection Hardness Score system as Grades 4, 3, 2 or 1 (corresponding to Schramek Grades V to II. Then, the patients were given oral sildenafil (50-100 mg and scored according to the International Index of Erectile Function (IIEF-5 questionnaire. The number of patients with penile rigidities of Schramek Grades II to V was 14, 18, 21, and 111, respectively. The IIEF-5 score was positively correlated with the refilling index of the penile cavernosal artery (r = 0.79, P< 0.05, the peak systolic velocity (r = 0.45, P< 0.05, and penile rigidity (r = 0.75, P< 0.05, and was negatively correlated with the end diastolic velocity (r = −0.74, P< 0.05. For patients with erectile dysfunction, both the IIEF-5 score after sildenafil administration, which is correlated with penile rigidity, and the hemodynamic parameters detected using color Doppler flow imaging may predict the effects of phosphodiesterase type 5 inhibitor treatment and could provide a reasonable model for the targeted-treatment of erectile dysfunction.

Doppler color flow mapping of peripheral vessels: Comparison of angiodynography with conventional duplex US

International Nuclear Information System (INIS)

Merritt, C.R.B.; Bluth, E.I.; Sullivan, M.A.

1986-01-01

A new Doppler color flow imager was compared to duplex US in the evaluation of carotid and peripheral vessels in 50 patients. A 7.5-MHz transducer permitted simultaneous high-resolution real-time imaging of Doppler flow and tissue. The system was found to have excellent image quality and Doppler sensitivity. Flow characteristics and velocity measurements obtained with this system correlated well with those obtained using the duplex scanner and were obtained more quickly than with the conventional system, allowing more complete assessment of flow characteristics. Color Doppler flow imaging appears to be an extremely promising method for the rapid and effective evaluation of peripheral vascular flow

WAMDII: The Wide Angle Michelson Doppler Imaging Interferometer

Science.gov (United States)

1992-01-01

As part of an effort to learn more about the upper atmosphere and how it is linked to the weather experienced each day, NASA and NRCC are jointly sponsoring the Wide Angle Michelson Doppler Imaging Interferometer (WAMDII) Mission. WAMDII will measure atmospheric temperature and wind speed in the upper atmosphere. In addition to providing data on the upper atmosphere, the wind speed and temperature readings WAMDII takes will also be highly useful in developing and updating computer simulated models of the upper atmosphere. These models are used in the design and testing of equipment and software for Shuttles, satellites, and reentry vehicles. In making its wind speed and temperature measurements, WAMDII examines the Earth's airglow, a faint photochemical luminescence caused by the influx of solar ultraviolet energy into the upper atmosphere. During periods of high solar flare activity, the amount of this UV energy entering the upper atmosphere increases, and this increase may effect airglow emissions.

Doppler imaging of hypoxic-ischemic encephalopathy in term neonates on the first day of life

International Nuclear Information System (INIS)

Wilczynska, M.; Stefanczyk, L.; Zieba, K.; Bieganski, T.; Gulczynska, E.

2004-01-01

Hypoxic-ischaemic encephalopathy (HIE) is the most important neurological cause of mortality and poor neurodevelopmental outcome in neonates and infants. The aim of the study was to perform routine transfontanellar US brain scanning together with doppler evaluation of blood flow in anterior cerebral artery in the group of neonates with perinatal asphyxia studied at the first day of their life. The study group consisted of asphyxiated neonates (n=11), birth weight 3576,0 ± 426,0 g, gestational age 39,4 ± 1,1 weeks, pH of cord arterial blood 6,89 ± 0,45, 1 st minute Apgar score 2 points. The control group were healthy neonates (n=20), , birth weight 3354,0 ± 378,0 g, gestational age 38,9 ± 1,8 weeks, pH of cord arterial blood 7,28 ± 0,41, 1 st minute Apgar score 8 points. As compared to healthy children asphyxiated neonates had significantly decreased RI value (right cerebral artery 0,53 ± 0,02 vs. 0,72 ± 0,02; left cerebral artery 0,55 ± 0,02 vs. 0,73 ± 0,02), despite not all of them had obvious HIE features in routine US examination. None of these neonates lived longer than 10 days. Doppler examination of cerebral blood flow in term neonates born with perinatal asphyxia could be valuable complementary method of US imaging, especially in those patients with very discreet or absent HIE features in routine US scan. Results of doppler imaging could serve as prognostic factor for clinical outcome. (author)

Standardization of the first-trimester fetal cardiac examination using spatiotemporal image correlation with tomographic ultrasound and color Doppler imaging.

Science.gov (United States)

Turan, S; Turan, O M; Ty-Torredes, K; Harman, C R; Baschat, A A

2009-06-01

The challenges of the first-trimester examination of the fetal heart may in part be overcome by technical advances in three-dimensional (3D) ultrasound techniques. Our aim was to standardize the first-trimester 3D imaging approach to the cardiac examination to provide the most consistent and accurate display of anatomy. Low-risk women with normal findings on first-trimester screening at 11 to 13 + 6 weeks had cardiac ultrasound using the following sequence: (1) identification of the four-chamber view; (2) four-dimensional (4D) volume acquisition with spatiotemporal image correlation (STIC) and color Doppler imaging (angle = 20 degrees, sweep 10 s); (3) offline, tomographic ultrasound imaging (TUI) analysis with standardized starting plane (four-chamber view), slice number and thickness; (4) assessment of fetal cardiac anatomy (four-chamber view, cardiac axis, size and symmetry, atrioventricular valves, great arteries and descending aorta) with and without color Doppler. 107 consecutive women (age, 16-42 years, body mass index 17.2-50.2 kg/m(2)) were studied. A minimum of three 3D volumes were obtained for each patient, transabdominally in 91.6%. Fetal motion artifact required acquisition of more than three volumes in 20%. The median time for TUI offline analysis was 100 (range, 60-240) s. Individual anatomic landmarks were identified in 89.7-99.1%. Visualization of all structures in one panel was observed in 91 patients (85%). Starting from a simple two-dimensional cardiac landmark-the four-chamber view-the standardized STIC-TUI technique enables detailed segmental cardiac evaluation of the normal fetal heart in the first trimester. (c) 2009 ISUOG.

Doppler optical cardiogram gated 2D color flow imaging at 1000 fps and 4D in vivo visualization of embryonic heart at 45 fps on a swept source OCT system.

Science.gov (United States)

Mariampillai, Adrian; Standish, Beau A; Munce, Nigel R; Randall, Cristina; Liu, George; Jiang, James Y; Cable, Alex E; Vitkin, I A; Yang, Victor X D

2007-02-19

We report a Doppler optical cardiogram gating technique for increasing the effective frame rate of Doppler optical coherence tomography (DOCT) when imaging periodic motion as found in the cardiovascular system of embryos. This was accomplished with a Thorlabs swept-source DOCT system that simultaneously acquired and displayed structural and Doppler images at 12 frames per second (fps). The gating technique allowed for ultra-high speed visualization of the blood flow pattern in the developing hearts of African clawed frog embryos (Xenopus laevis) at up to 1000 fps. In addition, four-dimensional (three spatial dimensions + temporal) Doppler imaging at 45 fps was demonstrated using this gating technique, producing detailed visualization of the complex cardiac motion and hemodynamics in a beating heart.

Cardiac carcinoid: tricuspid delayed hyperenhancement on cardiac 64-slice multidetector CT and magnetic resonance imaging.

LENUS (Irish Health Repository)

Martos, R

2012-02-01

INTRODUCTION: Carcinoid heart disease is a rare condition in adults. Its diagnosis can be easily missed in a patient presenting to a primary care setting. We revised the advantages of using coronary multidetector computed tomography (MDCT) and cardiac magnetic resonance imaging (MRI) in diagnosing this condition. MATERIALS AND METHODS: We studied a 65-year-old patient with carcinoid heart disease and right heart failure using transthoracic Doppler-echocardiogram, cardiac MDCT and MRI. Cardiac echocardiogram revealed marked thickening and retraction of the tricuspid leaflets with dilated right atrium and ventricle. Cardiac MDCT and MRI demonstrated fixation and retraction of the tricuspid leaflets with delayed contrast hyperenhancement of the tricuspid annulus. CONCLUSION: This case demonstrates fascinating imaging findings of cardiac carcinoid disease and highlights the increasing utility of contrast-enhanced MRI and cardiac MDCT in the diagnosis of this interesting condition.

Magnetic resonance imaging and three-dimensional ultrasound of carotid atherosclerosis: mapping regional differences.

Science.gov (United States)

Krasinski, Adam; Chiu, Bernard; Fenster, Aaron; Parraga, Grace

2009-04-01

To evaluate differences in carotid atherosclerosis measured using magnetic resonance imaging (MRI) and three-dimensional ultrasound (3DUS). Ten subject volunteers underwent carotid 3DUS and MRI (multislice black blood fast spin echo, T1-weighted contrast, double inversion recovery, 0.5 mm in-plane resolution, 2 mm slice, 3.0 T) within 1 hour. 3DUS and MR images were manually segmented by two observers providing vessel wall and lumen contours for quantification of vessel wall volume (VWV) and generation of carotid thickness maps. MRI VWV (1040 +/- 210 mm(3)) and 3DUS VWV (540 +/- 110 mm(3)) were significantly different (P Power Doppler US confirmed that heterogeneity in the common carotid artery in all patients resulted from apparent flow disturbances, not atherosclerotic plaque. MRI and 3DUS VWV were significantly different and carotid maps showed homogeneous thickness differences and heterogeneity in specific regions of interest identified as MR flow artifacts in the common carotid artery.

Magnetic resonance imaging of the prostate

DEFF Research Database (Denmark)

Iversen, P; Kjaer, L; Thomsen, C

1988-01-01

Magnetic resonance imaging offers new possibilities in investigation of the prostate gland. Current results of imaging and tissue discrimination in the evaluation of prostatic disease are reviewed. Magnetic resonance imaging may be useful in the staging of carcinoma of the prostate....

Diagnosis of right-sided varicocele: A retrospective comparative study between clinical examination, Doppler findings, US imaging and vascular anatomy at phlebography

International Nuclear Information System (INIS)

Cariati, Maurizio; Pieri, Stefano; Agresti, Paolo; Cariati, Massimiliano; Candito, Davide Fabio; Damiani, Giovanni; Marzano, Domenico

2012-01-01

Historically varicocele is diagnosed almost exclusively on the left side. The introduction of new imaging techniques has allowed the identification and characterization of right varicocele. This study aims to compare the diagnostic accuracy of various imaging techniques to data obtained using phlebography in the diagnosis of right varicocele. Patients treated for isolated right varicocele between 1992 and 2010 were retrospectively identified. Data from clinical examination, Doppler-USS, Color-Doppler-USS and Retrograde Phlebography were collected for each patient. 133 out of 4305 patients (3.1%) presented with an isolated right varicocele. 34 of these patients (25.6%) presented with palpable right varicocele. Doppler-USS identified various degrees of type I right venous reflux in 90 patients (67.7%). Phlebography showed venous reflux in all the patients (133), although with variability in terms of internal spermatic vein anatomy. Right varicocele is characterized by predictable anatomic features. Identification and characterization of these features is useful in guiding percutaneous treatment, allowing to optimize radiological display and reducing failure rate

Diagnosis of right-sided varicocele: A retrospective comparative study between clinical examination, Doppler findings, US imaging and vascular anatomy at phlebography

Energy Technology Data Exchange (ETDEWEB)

Cariati, Maurizio, E-mail: davide.candito@libero.it [U.O.C. Radiologia, A.O. San Carlo Borromeo, via Pio II 3, 20153 Milan (Italy); Pieri, Stefano, E-mail: stefano.pieri@scamilloforlanini.rm.it [U.O.C. Diagnostica per Immagini Cardioscienze, A.O. San Camillo - Forlanini, Piazza Carlo Forlanini 1, 00151 Rome (Italy); Agresti, Paolo, E-mail: paolo.agresti@scamilloforlanini.rm.it [U.O.C. Diagnostica per Immagini Cardioscienze, A.O. San Camillo - Forlanini, Piazza Carlo Forlanini 1, 00151 Rome (Italy); Cariati, Massimiliano, E-mail: massimiliano.cariati@kcl.ac.uk [Department of Academic Oncology, King' s College London, 3rd Floor Bermondsey Wing, Guy' s Hospital, Great Maze Pond, London SE1 9RT (United Kingdom); Candito, Davide Fabio, E-mail: davide.candito@yahoo.it [Scuola di Specializzazione in Radiodiagnostica, Facoltà di Medicina e Chirurgia, Università degli studi di Milano, via Festa del Perdono 7, 20122 Milan (Italy); Damiani, Giovanni, E-mail: damiani_giovanni@libero.it [Scuola di Specializzazione in Radiodiagnostica, Facoltà di Medicina e Chirurgia, Università degli studi di Milano, via Festa del Perdono 7, 20122 Milan (Italy); Marzano, Domenico, E-mail: domenico.marzano@scamilloforlanini.rm.it [U.O.C. Urologia, A.O. San Camillo - Forlanini, Piazza Carlo Forlanini 1, 00151 Rome (Italy)

2012-09-15

Historically varicocele is diagnosed almost exclusively on the left side. The introduction of new imaging techniques has allowed the identification and characterization of right varicocele. This study aims to compare the diagnostic accuracy of various imaging techniques to data obtained using phlebography in the diagnosis of right varicocele. Patients treated for isolated right varicocele between 1992 and 2010 were retrospectively identified. Data from clinical examination, Doppler-USS, Color-Doppler-USS and Retrograde Phlebography were collected for each patient. 133 out of 4305 patients (3.1%) presented with an isolated right varicocele. 34 of these patients (25.6%) presented with palpable right varicocele. Doppler-USS identified various degrees of type I right venous reflux in 90 patients (67.7%). Phlebography showed venous reflux in all the patients (133), although with variability in terms of internal spermatic vein anatomy. Right varicocele is characterized by predictable anatomic features. Identification and characterization of these features is useful in guiding percutaneous treatment, allowing to optimize radiological display and reducing failure rate.

Imaging of the hip joint. Computed tomography versus magnetic resonance imaging

Science.gov (United States)

Lang, P.; Genant, H. K.; Jergesen, H. E.; Murray, W. R.

1992-01-01

The authors reviewed the applications and limitations of computed tomography (CT) and magnetic resonance (MR) imaging in the assessment of the most common hip disorders. Magnetic resonance imaging is the most sensitive technique in detecting osteonecrosis of the femoral head. Magnetic resonance reflects the histologic changes associated with osteonecrosis very well, which may ultimately help to improve staging. Computed tomography can more accurately identify subchondral fractures than MR imaging and thus remains important for staging. In congenital dysplasia of the hip, the position of the nonossified femoral head in children less than six months of age can only be inferred by indirect signs on CT. Magnetic resonance imaging demonstrates the cartilaginous femoral head directly without ionizing radiation. Computed tomography remains the imaging modality of choice for evaluating fractures of the hip joint. In some patients, MR imaging demonstrates the fracture even when it is not apparent on radiography. In neoplasm, CT provides better assessment of calcification, ossification, and periosteal reaction than MR imaging. Magnetic resonance imaging, however, represents the most accurate imaging modality for evaluating intramedullary and soft-tissue extent of the tumor and identifying involvement of neurovascular bundles. Magnetic resonance imaging can also be used to monitor response to chemotherapy. In osteoarthrosis and rheumatoid arthritis of the hip, both CT and MR provide more detailed assessment of the severity of disease than conventional radiography because of their tomographic nature. Magnetic resonance imaging is unique in evaluating cartilage degeneration and loss, and in demonstrating soft-tissue alterations such as inflammatory synovial proliferation.

Magnetic resonance imaging of the prostate

DEFF Research Database (Denmark)

Iversen, P; Kjaer, L; Thomsen, C

1987-01-01

Magnetic resonance imaging offers new possibilities in the investigation of the prostate. The current results of imaging and tissue discrimination in the evaluation of prostatic disease are reviewed. Magnetic resonance imaging may be of value in the staging of carcinoma of the prostate....

Clinical usefulness of cardiac cine magnetic resonance imaging in patients with atrial fibrillation

Energy Technology Data Exchange (ETDEWEB)

Sakakura, Kazuyoshi; Anno, Hirofumi; Kondo, Takeshi [Fujita Health Univ., Toyoake, Aichi (Japan); and others

1993-05-01

We studied the clinical usefulness of cine mode magnetic resonance (MR) imaging in patients with atrial fibrillation (AF) from aspects of image quality and cardiac function. The signal-to-noise (S/N) ratio in the myocardium was significantly (p<0.05) lower in patients with AF than those with normal sinus rhythm. Two radiologists who did not know any patient's information evaluated the image quality visually by marking method on a scale of 12 points. There was no difference of image quality between the two groups. The standard deviation of R-R interval was significantly (r=-0.92, p<0.001) correlated with the S/N ratio in myocardium. Consequently, it was not favorable to estimate visually cardiac cine MR image in patients with AF, when standard deviation of R-R interval was large. The left ventricular (LV) end diastolic, end systolic and stroke volumes and ejection fraction were closely (r=0.82[approx]0.95, p<0.05[approx]0.001) correlated between MR imaging and M-mode echocardiography, respectively. The ability to detect left side valvular regurgitation was almost equal in both MR imaging and color Doppler echocardiography. This result was coincided to previous papers in patients with normal sinus rhythm. In conclusion, cine mode MR imaging was also useful to analyze cardiac function and detect valvular regurgitation in patients with AF. (author).

Color-flow Doppler imaging in suspected extremity venous thrombosis

International Nuclear Information System (INIS)

Foley, W.D.; Middleton, W.D.; Lawson, T.L.; Hinson, G.W.; Puller, D.R.

1987-01-01

Color-flow Doppler imaging (CFDI) (Quanatum, 5 and 7.5 MHz, linear array) has been performed on 23 extremities (nine positive for venous thrombosis, 14 negative) with venographic correlation. CFDI criteria evaluated were venous color-flow respiratory variation, augmentation, compressibility, valve competence, and intraluminal echogenic filling defects. Both CFDI and venography were evaluated independently and prospectively. CFDI and venography agreed in all six cases of femoral vein thrombosis and eight of nine cases of popliteal vein thrombosis. CFDI was negative in one instance of recanalized popliteal vein thrombosis. Recanalized femoral vein thrombosis was documented in three patients by CFDI when the vein was nonopacified on conventional venography. CFDI provides a rapid and accurate assessment of the femoral popliteal venous system and can distinguish an occluded from a recanalized thrombus. Initial experience with auxiliary subclavian venous thrombus has produced equally accurate results

Magnetic resonance imaging the basics

CERN Document Server

Constantinides, Christakis

2014-01-01

Magnetic resonance imaging (MRI) is a rapidly developing field in basic applied science and clinical practice. Research efforts in this area have already been recognized with five Nobel prizes awarded to seven Nobel laureates in the past 70 years. Based on courses taught at The Johns Hopkins University, Magnetic Resonance Imaging: The Basics provides a solid introduction to this powerful technology. The book begins with a general description of the phenomenon of magnetic resonance and a brief summary of Fourier transformations in two dimensions. It examines the fundamental principles of physics for nuclear magnetic resonance (NMR) signal formation and image construction and provides a detailed explanation of the mathematical formulation of MRI. Numerous image quantitative indices are discussed, including (among others) signal, noise, signal-to-noise, contrast, and resolution. The second part of the book examines the hardware and electronics of an MRI scanner and the typical measurements and simulations of m...

Power and color Doppler ultrasound settings for inflammatory flow

DEFF Research Database (Denmark)

Torp-Pedersen, Søren; Christensen, Robin; Szkudlarek, Marcin

2015-01-01

OBJECTIVE: To determine how settings for power and color Doppler ultrasound sensitivity vary on different high- and intermediate-range ultrasound machines and to evaluate the impact of these changes on Doppler scoring of inflamed joints. METHODS: Six different types of ultrasound machines were used....... On each machine, the factory setting for superficial musculoskeletal scanning was used unchanged for both color and power Doppler modalities. The settings were then adjusted for increased Doppler sensitivity, and these settings were designated study settings. Eleven patients with rheumatoid arthritis (RA......) with wrist involvement were scanned on the 6 machines, each with 4 settings, generating 264 Doppler images for scoring and color quantification. Doppler sensitivity was measured with a quantitative assessment of Doppler activity: color fraction. Higher color fraction indicated higher sensitivity. RESULTS...

Investigating the effect of a targets time-varying doppler generating axis of rotation on isar image distortion

CSIR Research Space (South Africa)

Abdul Gaffar, MY

2007-10-01

Full Text Available , contributes to ISAR image blurring. Quaternion algebra is used to aid the characterisation of a time-varying Doppler generating axis of rotation on the migration through cross-range cells. Real motion data of a sailing yacht is used to examine the effects of 3...

Asset of Doppler Vascular Imaging and CTA in Diagnosis of Coagulation Disturbances in Pregnancy and Puerperium - case study

International Nuclear Information System (INIS)

Leskova, M.; Slobodnikova, J.

2009-01-01

Importance of earlier diagnosis of trombophilia. Trombophilia - its impression on development venous trombosis specially in the case of young woman with repeated spontaneous abortions. Value of not-invasive imaging methods (Doppler sonography and CT angiography ) in diagnosis deep phlebotrombosis. (author)

Formulation of novel lipid-coated magnetic nanoparticles as the probe for in vivo imaging

Directory of Open Access Journals (Sweden)

Mou Chung-Yuan

2009-09-01

Full Text Available Abstract Background Application of superparamagnetic iron oxide nanoparticles (SPIOs as the contrast agent has improved the quality of magnetic resonance (MR imaging. Low efficiency of loading the commercially available iron oxide nanoparticles into cells and the cytotoxicity of previously formulated complexes limit their usage as the image probe. Here, we formulated new cationic lipid nanoparticles containing SPIOs feasible for in vivo imaging. Methods Hydrophobic SPIOs were incorporated into cationic lipid 1,2-dioleoyl-3-(trimethylammonium propane (DOTAP and polyethylene-glycol-2000-1,2-distearyl-3-sn-phosphatidylethanolamine (PEG-DSPE based micelles by self-assembly procedure to form lipid-coated SPIOs (L-SPIOs. Trace amount of Rhodamine-dioleoyl-phosphatidylethanolamine (Rhodamine-DOPE was added as a fluorescent indicator. Particle size and zeta potential of L-SPIOs were determined by Dynamic Light Scattering (DLS and Laser Doppler Velocimetry (LDV, respectively. HeLa, PC-3 and Neuro-2a cells were tested for loading efficiency and cytotoxicity of L-SPIOs using fluorescent microscopy, Prussian blue staining and flow cytometry. L-SPIO-loaded CT-26 cells were tested for in vivo MR imaging. Results The novel formulation generates L-SPIOs particle with the average size of 46 nm. We showed efficient cellular uptake of these L-SPIOs with cationic surface charge into HeLa, PC-3 and Neuro-2a cells. The L-SPIO-loaded cells exhibited similar growth potential as compared to unloaded cells, and could be sorted by a magnet stand over ten-day duration. Furthermore, when SPIO-loaded CT-26 tumor cells were injected into Balb/c mice, the growth status of these tumor cells could be monitored using optical and MR images. Conclusion We have developed a novel cationic lipid-based nanoparticle of SPIOs with high loading efficiency, low cytotoxicity and long-term imaging signals. The results suggested these newly formulated non-toxic lipid-coated magnetic

Renal venous thrombosis in an infant with predisposing thrombotic factors: color Doppler ultrasound and MR evaluation

Energy Technology Data Exchange (ETDEWEB)

Argyropoulou, Maria I.; Papadopoulou, Frederica; Nikolopoulos, Pangiotis [Department of Radiology, Medical School, University of Ioannina, 45110, Ioannina (Greece); Giapros, Vassilios I.; Drougia, Aikaterini A.; Andronikou, Styliani [Neonatology Clinic, Medical School, University of Ioannina, 45110, Ioannina (Greece); Vartholomatos, Georgios A. [Department of Haematology, Medical School, University of Ioannina, 45110, Ioannina (Greece)

2003-08-01

We report a case of a neonate with hereditary thrombophilia presenting with renal venous thrombosis (RVT). Early color Doppler findings of RVT were lacking venous flow, and the arterial diastolic flow was reversed. This very high-resistance arterial flow is for the first time described in neonatal RVT. Magnetic resonance imaging showed low signal intensity of the renal pyramids on T1- and T2-weighted images, suggesting acute hemorrhage. After intravenous contrast injection, persistent cortical enhancement was observed along with lack of medullary enhancement. Despite the progressive reestablishment of some venous drainage, the kidney showed atrophy and loss of function. (orig.)

Renal venous thrombosis in an infant with predisposing thrombotic factors: color Doppler ultrasound and MR evaluation

International Nuclear Information System (INIS)

Argyropoulou, Maria I.; Papadopoulou, Frederica; Nikolopoulos, Pangiotis; Giapros, Vassilios I.; Drougia, Aikaterini A.; Andronikou, Styliani; Vartholomatos, Georgios A.

2003-01-01

We report a case of a neonate with hereditary thrombophilia presenting with renal venous thrombosis (RVT). Early color Doppler findings of RVT were lacking venous flow, and the arterial diastolic flow was reversed. This very high-resistance arterial flow is for the first time described in neonatal RVT. Magnetic resonance imaging showed low signal intensity of the renal pyramids on T1- and T2-weighted images, suggesting acute hemorrhage. After intravenous contrast injection, persistent cortical enhancement was observed along with lack of medullary enhancement. Despite the progressive reestablishment of some venous drainage, the kidney showed atrophy and loss of function. (orig.)

Adaptation of Dunn Solar Telescope for Jovian Doppler spectro imaging

Science.gov (United States)

Underwood, Thomas A.; Voelz, David; Schmider, François-Xavier; Jackiewicz, Jason; Dejonghe, Julien; Bresson, Yves; Hull, Robert; Goncalves, Ivan; Gualme, Patrick; Morand, Frédéric; Preis, Olivier

2017-09-01

This paper describes instrumentation used to adapt the Dunn Solar Telescope (DST) located on Sacramento Peak in Sunspot, NM for observations using the Doppler Spectro Imager (DSI). The DSI is based on a Mach-Zehnder interferometer and measures the Doppler shift of solar lines allowing for the study of atmospheric dynamics of giant planets and the detection of their acoustic oscillations. The instrumentation is being designed and built through a collaborative effort between a French team from the Observatoire de la Cote d'Azur (OCA) that designed the DSI and a US team at New Mexico State University (NMSU). There are four major components that couple the DSI to the DST: a guider/tracker, fast steering mirror (FSM), pupil stabilizer and transfer optics. The guider/tracker processes digital video to centroid-track the planet and outputs voltages to the DST's heliostat controls. The FSM removes wavefront tip/tilt components primarily due to turbulence and the pupil stabilizer removes any slow pupil "wander" introduced by the telescope's heliostat/turret arrangement. The light received at a science port of the DST is sent through the correction and stabilization components and into the DSI. The FSM and transfer optics designs are being provided by the OCA team and serve much the same functions as they do for other telescopes at which DSI observations have been conducted. The pupil stabilization and guider are new and are required to address characteristics of the DST.

Perfusion of burn wounds assessed by Laser Doppler Imaging is related to burn depth and healing time

NARCIS (Netherlands)

Kloppenberg, FWH; Beerthuizen, GIJM; ten Duis, H. J.

Average perfusion in various burn wounds was assessed using Laser Doppler Imaging (LDI). The time necessary for a complete healing of the wound was compared to the results of the LDI measurements. A certain depth of burn was associated with a typical pattern of perfusion in the course of time. There

Recommendations for terminology and display for doppler echocardiography

International Nuclear Information System (INIS)

Anon.

1986-01-01

Doppler echocardiography has recently emerged as a major noninvasive technique with many applications in cardiology. To a large extent, this has been based upon a combination of clinical and engineering advances which now make possible the use of quantitative Doppler echocardiography in combination with two-dimensional imaging for measurement of volume flows, transvalve gradients, and other physiologic flow parameters which reflect cardiac function. It was the purpose of this Committee to provide a glossary of terms which could be used in standard fashion for papers and discussions related to Doppler echocardiography. As part of its task, the Committee also undertook an attempt to recommend a standard for display of Doppler information which would be useful, both for manufacturers and for clinicians. The document, therefore, includes: Section I, the Committee's recommendations for Doppler display. Section II, the glossary of Doppler terms, related to engineering and to clinical applications

Magnetic particle imaging of blood coagulation

Energy Technology Data Exchange (ETDEWEB)

Murase, Kenya, E-mail: murase@sahs.med.osaka-u.ac.jp; Song, Ruixiao; Hiratsuka, Samu [Department of Medical Physics and Engineering, Division of Medical Technology and Science, Faculty of Health Science, Graduate School of Medicine, Osaka University, Osaka 565-0871 (Japan)

2014-06-23

We investigated the feasibility of visualizing blood coagulation using a system for magnetic particle imaging (MPI). A magnetic field-free line is generated using two opposing neodymium magnets and transverse images are reconstructed from the third-harmonic signals received by a gradiometer coil, using the maximum likelihood-expectation maximization algorithm. Our MPI system was used to image the blood coagulation induced by adding CaCl{sub 2} to whole sheep blood mixed with magnetic nanoparticles (MNPs). The “MPI value” was defined as the pixel value of the transverse image reconstructed from the third-harmonic signals. MPI values were significantly smaller for coagulated blood samples than those without coagulation. We confirmed the rationale of these results by calculating the third-harmonic signals for the measured viscosities of samples, with an assumption that the magnetization and particle size distribution of MNPs obey the Langevin equation and log-normal distribution, respectively. We concluded that MPI can be useful for visualizing blood coagulation.

ACHIEVING CONSISTENT DOPPLER MEASUREMENTS FROM SDO /HMI VECTOR FIELD INVERSIONS

International Nuclear Information System (INIS)

Schuck, Peter W.; Antiochos, S. K.; Leka, K. D.; Barnes, Graham

2016-01-01

NASA’s Solar Dynamics Observatory is delivering vector magnetic field observations of the full solar disk with unprecedented temporal and spatial resolution; however, the satellite is in a highly inclined geosynchronous orbit. The relative spacecraft–Sun velocity varies by ±3 km s −1 over a day, which introduces major orbital artifacts in the Helioseismic Magnetic Imager (HMI) data. We demonstrate that the orbital artifacts contaminate all spatial and temporal scales in the data. We describe a newly developed three-stage procedure for mitigating these artifacts in the Doppler data obtained from the Milne–Eddington inversions in the HMI pipeline. The procedure ultimately uses 32 velocity-dependent coefficients to adjust 10 million pixels—a remarkably sparse correction model given the complexity of the orbital artifacts. This procedure was applied to full-disk images of AR 11084 to produce consistent Dopplergrams. The data adjustments reduce the power in the orbital artifacts by 31 dB. Furthermore, we analyze in detail the corrected images and show that our procedure greatly improves the temporal and spectral properties of the data without adding any new artifacts. We conclude that this new procedure makes a dramatic improvement in the consistency of the HMI data and in its usefulness for precision scientific studies.

Achieving Consistent Doppler Measurements from SDO/HMI Vector Field Inversions

Science.gov (United States)

Schuck, Peter W.; Antiochos, S. K.; Leka, K. D.; Barnes, Graham

2016-01-01

NASA's Solar Dynamics Observatory is delivering vector magnetic field observations of the full solar disk with unprecedented temporal and spatial resolution; however, the satellite is in a highly inclined geosynchronous orbit. The relative spacecraft-Sun velocity varies by +/-3 kms-1 over a day, which introduces major orbital artifacts in the Helioseismic Magnetic Imager (HMI) data. We demonstrate that the orbital artifacts contaminate all spatial and temporal scales in the data. We describe a newly developed three-stage procedure for mitigating these artifacts in the Doppler data obtained from the Milne-Eddington inversions in the HMI pipeline. The procedure ultimately uses 32 velocity-dependent coefficients to adjust 10 million pixels-a remarkably sparse correction model given the complexity of the orbital artifacts. This procedure was applied to full-disk images of AR 11084 to produce consistent Dopplergrams. The data adjustments reduce the power in the orbital artifacts by 31 dB. Furthermore, we analyze in detail the corrected images and show that our procedure greatly improves the temporal and spectral properties of the data without adding any new artifacts. We conclude that this new procedure makes a dramatic improvement in the consistency of the HMI data and in its usefulness for precision scientific studies.

Children's (Pediatric) Magnetic Resonance Imaging

Medline Plus

Full Text Available ... magnetic resonance imaging (MRI) uses a powerful magnetic field, radio waves and a computer to produce detailed ... problems, medications, recent surgeries and allergies. The magnetic field is not harmful, but it may cause some ...

The role of magnetic resonance imaging and ultrasound in patients with adnexal masses

International Nuclear Information System (INIS)

Sohaib, S.A.; Mills, T.D.; Sahdev, A.; Webb, J.A.W.; VanTrappen, P.O.; Jacobs, I.J.; Reznek, R.H.

2005-01-01

AIMS: To evaluate the accuracy of ultrasonography (US) and magnetic resonance imaging (MRI) in characterizing adnexal masses, and to determine which patients may benefit from MRI. METHODS: We prospectively studied 72 women (mean age 53 years, range 19 to 86 years) with clinically suspected adnexal masses. A single experienced sonographer performed transabdominal and transvaginal greyscale spectral and colour Doppler examinations. MRI was carried out on a 1.5T system using T1, T2 and fat-suppressed T1-weighted sequences before and after intravenous injection of gadolinium. The adnexal masses were categorized as benign or malignant without knowledge of clinical details, according to the imaging features which were compared with the surgical and pathological findings. RESULTS: For characterizing lesions as malignant, the sensitivity, specificity and accuracy of MRI were 96.6%, 83.7% and 88.9%, respectively, and of US were 100%, 39.5% and 63.9%, respectively. MRI was more specific (p<0.05) than US. Both MRI and US correctly diagnosed 17 (24%) cases with benign and 28 (39%) cases with malignant masses. MRI correctly diagnosed 19 (26%) cases with benign lesion(s), which on US were thought to be malignant. The age, menopausal status and CA-125 levels in these women made benign disease likely, but US features were suggestive of malignancy (large masses and solid-cystic lesions with nodules). CONCLUSION: MRI is more specific and accurate than US and Doppler assessment for characterizing adnexal masses. Women who clinically have a relatively low risk of malignancy but who have complex sonographic features may benefit from MRI

Medulloblastoma: correlation among findings of conventional magnetic resonance imaging, diffusion-weighted imaging and proton magnetic resonance spectroscopy

Energy Technology Data Exchange (ETDEWEB)

Fonte, Mariana Vieira de Melo da; Otaduy, Maria Concepcion Garcia; Lucato, Leandro Tavares; Reed, Umbertina Conti; Leite, Claudia da Costa [Universidade de Sao Paulo (USP), Sao Paulo, SP (Brazil). Hospital das Clinicas. Inst. de Radiologia]. E-mail: mvmfonte@uol.com.br; Costa, Maria Olivia Rodrigues; Amaral, Raquel Portugal Guimaraes [Universidade de Sao Paulo (USP), Sao Paulo, SP (Brazil). Faculdade de Medicina. Dept. de Radiologia; Reed, Umbertina Conti [Universidade de Sao Paulo (USP), Sao Paulo, SP (Brazil). Faculdade de Medicina. Dept. de Neurologia; Rosemberg, Sergio [Universidade de Sao Paulo (USP), Sao Paulo, SP (Brazil). Hospital das Clinicas. Dept. de Patologia

2008-11-15

To correlate imaging findings of medulloblastomas at conventional magnetic resonance imaging, diffusion-weighted imaging and proton magnetic resonance spectroscopy, comparing them with data in the literature. Preoperative magnetic resonance imaging studies of nine pediatric patients with histologically confirmed medulloblastomas (eight desmoplastic medulloblastoma, and one giant cell medulloblastoma) were retrospectively reviewed, considering demographics as well as tumors characteristics such as localization, morphology, signal intensity, contrast-enhancement, dissemination, and diffusion-weighted imaging and spectroscopy findings. In most of cases the tumors were centered in the cerebellar vermis (77.8%), predominantly solid (88.9%), hypointense on T 1-weighted images and intermediate/hyperintense on T 2-FLAIR-weighted images, with heterogeneous enhancement (100%), tumor dissemination/extension (77.8%) and limited water molecule mobility (100%). Proton spectroscopy acquired with STEAM technique (n = 6) demonstrated decreased Na a / Cr ratio (83.3%) and increased Co/Cr (100%) and ml/Cr (66.7%) ratios; and with PRESS technique (n = 7) demonstrated lactate peak (57.1%). Macroscopic magnetic resonance imaging findings in association with biochemical features of medulloblastomas have been useful in the differentiation among the most frequent posterior fossa tumors. (author)

Medulloblastoma: correlation among findings of conventional magnetic resonance imaging, diffusion-weighted imaging and proton magnetic resonance spectroscopy

International Nuclear Information System (INIS)

Fonte, Mariana Vieira de Melo da; Otaduy, Maria Concepcion Garcia; Lucato, Leandro Tavares; Reed, Umbertina Conti; Leite, Claudia da Costa; Costa, Maria Olivia Rodrigues; Amaral, Raquel Portugal Guimaraes; Reed, Umbertina Conti; Rosemberg, Sergio

2008-01-01

To correlate imaging findings of medulloblastomas at conventional magnetic resonance imaging, diffusion-weighted imaging and proton magnetic resonance spectroscopy, comparing them with data in the literature. Preoperative magnetic resonance imaging studies of nine pediatric patients with histologically confirmed medulloblastomas (eight desmoplastic medulloblastoma, and one giant cell medulloblastoma) were retrospectively reviewed, considering demographics as well as tumors characteristics such as localization, morphology, signal intensity, contrast-enhancement, dissemination, and diffusion-weighted imaging and spectroscopy findings. In most of cases the tumors were centered in the cerebellar vermis (77.8%), predominantly solid (88.9%), hypointense on T 1-weighted images and intermediate/hyperintense on T 2-FLAIR-weighted images, with heterogeneous enhancement (100%), tumor dissemination/extension (77.8%) and limited water molecule mobility (100%). Proton spectroscopy acquired with STEAM technique (n = 6) demonstrated decreased Na a / Cr ratio (83.3%) and increased Co/Cr (100%) and ml/Cr (66.7%) ratios; and with PRESS technique (n = 7) demonstrated lactate peak (57.1%). Macroscopic magnetic resonance imaging findings in association with biochemical features of medulloblastomas have been useful in the differentiation among the most frequent posterior fossa tumors. (author)

Implementation and Comparison of Acoustic Travel-Time Measurement Procedures for the Solar Dynamics Observatory-Helioseismic and Magnetic Imager Time-Distance Helioseismology Pipeline

Science.gov (United States)

Couvidat, S.; Zhao, J.; Birch, A. C.; Kosovichev, A. G.; Duvall, Thomas L., Jr.; Parchevsky, K.; Scherrer, P. H.

2010-01-01

The Helioseismic and Magnetic Imager (HMI) instrument onboard the Solar Dynamics Observatory (SDO) satellite is designed to produce high-resolution Doppler-velocity maps of oscillations at the solar surface with high temporal cadence. To take advantage of these high-quality oscillation data, a time - distance helioseismology pipeline (Zhao et al., Solar Phys. submitted, 2010) has been implemented at the Joint Science Operations Center (JSOC) at Stanford University. The aim of this pipeline is to generate maps of acoustic travel times from oscillations on the solar surface, and to infer subsurface 3D flow velocities and sound-speed perturbations. The wave travel times are measured from cross-covariances of the observed solar oscillation signals. For implementation into the pipeline we have investigated three different travel-time definitions developed in time - distance helioseismology: a Gabor-wavelet fitting (Kosovichev and Duvall, SCORE'96: Solar Convection and Oscillations and Their Relationship, ASSL, Dordrecht, 241, 1997), a minimization relative to a reference cross-covariance function (Gizon and Birch, Astrophys. J. 571, 966, 2002), and a linearized version of the minimization method (Gizon and Birch, Astrophys. J. 614, 472, 2004). Using Doppler-velocity data from the Michelson Doppler Imager (MDI) instrument onboard SOHO, we tested and compared these definitions for the mean and difference traveltime perturbations measured from reciprocal signals. Although all three procedures return similar travel times in a quiet-Sun region, the method of Gizon and Birch (Astrophys. J. 614, 472, 2004) gives travel times that are significantly different from the others in a magnetic (active) region. Thus, for the pipeline implementation we chose the procedures of Kosovichev and Duvall (SCORE'96: Solar Convection and Oscillations and Their Relationship, ASSL, Dordrecht, 241, 1997) and Gizon and Birch (Astrophys. J. 571, 966, 2002). We investigated the relationships among

Magnonic holographic imaging of magnetic microstructures

Energy Technology Data Exchange (ETDEWEB)

Gutierrez, D.; Chiang, H.; Bhowmick, T.; Volodchenkov, A.D.; Ranjbar, M.; Liu, G.; Jiang, C.; Warren, C. [Department of Electrical and Computer Engineering, University of California - Riverside, Riverside, CA 92521 (United States); Khivintsev, Y.; Filimonov, Y. [Kotelnikov Institute of Radioengineering and Electronics of Russian Academy of Sciences, Saratov Branch, Saratov 410019 (Russian Federation); Saratov State University, Saratov 410012 (Russian Federation); Garay, J.; Lake, R.; Balandin, A.A. [Department of Electrical and Computer Engineering, University of California - Riverside, Riverside, CA 92521 (United States); Khitun, A., E-mail: akhitun@engr.ucr.edu [Department of Electrical and Computer Engineering, University of California - Riverside, Riverside, CA 92521 (United States)

2017-04-15

We propose and demonstrate a technique for magnetic microstructure imaging via their interaction with propagating spin waves. In this approach, the object of interest is placed on top of a magnetic testbed made of material with low spin wave damping. There are micro-antennas incorporated in the testbed. Two of these antennas are used for spin wave excitation while another one is used for the detecting of inductive voltage produced by the interfering spin waves. The measurements are repeated for different phase differences between the spin wave generating antennas which is equivalent to changing the angle of illumination. The collected data appear as a 3D plot – the holographic image of the object. We present experimental data showing magnonic holographic images of a low-coercivity Si/Co sample, a high-coercivity sample made of SrFe{sub 12}O{sub 19} and a diamagnetic copper sample. We also present images of the three samples consisting of a different amount of SrFe{sub 12}O{sub 19} powder. The imaging was accomplished on a Y{sub 3}Fe{sub 2}(FeO{sub 4}){sub 3} testbed at room temperature. The obtained data reveal the unique magnonic signatures of the objects. Experimental data is complemented by the results of numerical modeling, which qualitatively explain the characteristic features of the images. Potentially, magnonic holographic imaging may complement existing techniques and be utilized for non-destructive in-situ magnetic object characterization. The fundamental physical limits of this approach are also discussed. - Highlights: • A technique for magnetic microstructure imaging via their interaction with propagating spin waves is proposed. • In this technique, magnetic structures appear as 3D objects. • Several holographic images of magnetic microstructures are presented.

Doppler-shifted fluorescence imaging of velocity fields in supersonic reacting flows

Science.gov (United States)

Allen, M. G.; Davis, S. J.; Kessler, W. J.; Sonnenfroh, D. M.

1992-01-01

The application of Doppler-shifted fluorescence imaging of velocity fields in supersonic reacting flows is analyzed. Focussing on fluorescence of the OH molecule in typical H2-air Scramjet flows, the effects of uncharacterized variations in temperature, pressure, and collisional partner composition across the measurement plane are examined. Detailed measurements of the (1,0) band OH lineshape variations in H2-air combustions are used, along with single-pulse and time-averaged measurements of an excimer-pumped dye laser, to predict the performance of a model velocimeter with typical Scramjet flow properties. The analysis demonstrates the need for modification and control of the laser bandshape in order to permit accurate velocity measurements in the presence of multivariant flow properties.

Magnetic resonance imaging of the central nervous system

International Nuclear Information System (INIS)

Brant-Zawadzki, M.; Norman, D.

1987-01-01

This book presents the papers on technological advancement and diagnostic uses g magnetic resonance imaging. A comparative evaluation with computerized tomography is presented. Topics covered are imaging principles g magnetic resonance;instrumentation of magnetic resonance (MR);pathophysiology;quality and limitations g images;NMR imaging of brain and spinal cord;MR spectroscopy and its applications;neuroanatomy;Congenital malformations of brain and MR imaging;planning g MR imaging of spine and head and neck imaging

Dynamics of contrast enhancement in MR imaging and power Doppler ultrasonography of solid breast lesions

International Nuclear Information System (INIS)

Reinikainen, H.; Paeaekkoe, E.; Suramo, I.; Paeivaensalo, M.; Rissanen, T.

2002-01-01

Purpose: To evaluate the dynamics of contrast enhancement in solid breast lesions at contrast-enhanced MR imaging and power Doppler ultrasonography (US) and to compare the methods to histology and to each other. Material and Methods: Forty breast lesions were prospectively examined with dynamic MR and power Doppler US. Time-signal intensity curves of enhancement were obtained for both methods. The shape of the curve was analyzed to be benign, indeterminate or malignant. The curves were also analyzed quantitatively by calculating the slope of the curve and the area under the curve (both methods), relative enhancement (MR), and time to peak (US). The lesions were divided into malignant lesions, fibroadenomas, and other benign lesions. The results were compared to histology. Results: In the subjective analysis of the MR curve in differentiating between benign and malignant lesions the accuracy was 90%. The MR curve also enabled differentiation between fibroadenomas and malignancies. The accuracy of the US curve was 38%. Quantitatively, statistically significant differences were found using all the MR variables, except between malignancies and fibroadenomas. Using the US variables, no significant difference was found between the groups. Conclusion: The dynamics of contrast-enhanced MR were reliable in the differential diagnosis of solid breast lesions, but contrast-enhanced power Doppler US was of limited value

Performance evaluation of an all-fiber image-reject homodyne coherent Doppler wind lidar

DEFF Research Database (Denmark)

Abari, Cyrus F.; Pedersen, Anders Tegtmeier; Dellwik, Ebba

2015-01-01

The main purpose of this study is to evaluate the near-zero wind velocity measurement performance of two separate 1.5 µm all-fiber coherent Doppler lidars (CDLs). The performance characterization is carried out through the presentation of the results from two separate atmospheric field campaigns....... In one campaign, a recently developed continuous wave (CW) CDL benefiting from an image-reject front-end was deployed. The other campaign utilized a different CW CDL, benefiting from a heterodyne receiver with intermediate-frequency (IF) sampling. In both field campaigns the results are compared against...

Exercise and Cardiac Function by Tissue Doppler Imaging. The Copenhagen City Heart Study

DEFF Research Database (Denmark)

Joseph, Gowsini; Sogaard, Peter; Nielsen, Gitte

2016-01-01

diastolic (e') and late diastolic (a') velocities were measured by color TDI. Longitudinal displacement (LD) was calculated from the velocity curve during ejection. Statistical tests were performed by linear univariate and multivariable regression analyses, in relation to age groups (lt;50years, 50-65 years......Introduction: TDI (Tissue Doppler Imaging) is a sensitive marker of myocardial dysfunction and mortality in heart disease and in the general population. Regular physical activity is associated with risk reduction in coronary heart disease and mortality. There is a need for studies to clarify...

Exercise and Cardiac Function by Tissue Doppler Imaging. The Copenhagen City Heart Study

DEFF Research Database (Denmark)

Joseph, Gowsini; Sogaard, Peter; Nielsen, Gitte

diastolic (e') and late diastolic (a') velocities were measured by color TDI. Longitudinal displacement (LD) was calculated from the velocity curve during ejection. Statistical tests were performed by linear univariate and multivariable regression analyses, in relation to age groups (lt;50years, 50-65 years......Introduction: TDI (Tissue Doppler Imaging) is a sensitive marker of myocardial dysfunction and mortality in heart disease and in the general population. Regular physical activity is associated with risk reduction in coronary heart disease and mortality. There is a need for studies to clarify...

Magnetic imager and method

Science.gov (United States)

Powell, James; Reich, Morris; Danby, Gordon

1997-07-22

A magnetic imager 10 includes a generator 18 for practicing a method of applying a background magnetic field over a concealed object, with the object being effective to locally perturb the background field. The imager 10 also includes a sensor 20 for measuring perturbations of the background field to detect the object. In one embodiment, the background field is applied quasi-statically. And, the magnitude or rate of change of the perturbations may be measured for determining location, size, and/or condition of the object.

Evaluation of regional wall motion abnormalities of the heart. Comparison with Doppler tissue echocardiography, MR-tagging and levocardiography

International Nuclear Information System (INIS)

Kivelitz, D.E.; Enzweiler, C.N.H.; Hamm, B.; Borges, A.C.; Walde, T.; Rutsch, W.; Baumann, G.

2004-01-01

Purpose: To compare the visual analysis of magnetic resonance imaging (MRI) with the tagging technique and Doppler tissue echocardiography with invasive ventriculography in detecting and quantifying regional left ventricular wall motion abnormalities. Materials and Methods: Sixteen patients with coronary artery disease and a history of prior myocardial infarction underwent invasive ventriculography. Doppler tissue echocardiography and MR-tagging within one week. Regional wall motion abnormalities (WMA) were detected in all patients. WMA were graded as normal=1; hypokinetic=2; akinetic=3; or dyskinetic=4. For agreement between MRI, echocardiography, and ventriculography the kappa coefficient (κ) according to Cohen was calculated. Results: The kappa coefficient (κ) was 0.962 for agreement between MRI and echocardiography and 0.602 for agreement between MRI and ventriculography as well as between echocardiography and ventriculography. Conclusion: Reliable analysis of regional left ventricular wall motion abnormalities is feasible using visual analysis of MR-tagging. MRI and Doppler tissue echocardiography detect more WMA than invasive ventriculography and grade them as more severe. (orig.)

Laser Doppler imaging of cutaneous blood flow through transparent face masks: a necessary preamble to computer-controlled rapid prototyping fabrication with submillimeter precision.

Science.gov (United States)

Allely, Rebekah R; Van-Buendia, Lan B; Jeng, James C; White, Patricia; Wu, Jingshu; Niszczak, Jonathan; Jordan, Marion H

2008-01-01

A paradigm shift in management of postburn facial scarring is lurking "just beneath the waves" with the widespread availability of two recent technologies: precise three-dimensional scanning/digitizing of complex surfaces and computer-controlled rapid prototyping three-dimensional "printers". Laser Doppler imaging may be the sensible method to track the scar hyperemia that should form the basis of assessing progress and directing incremental changes in the digitized topographical face mask "prescription". The purpose of this study was to establish feasibility of detecting perfusion through transparent face masks using the Laser Doppler Imaging scanner. Laser Doppler images of perfusion were obtained at multiple facial regions on five uninjured staff members. Images were obtained without a mask, followed by images with a loose fitting mask with and without a silicone liner, and then with a tight fitting mask with and without a silicone liner. Right and left oblique images, in addition to the frontal images, were used to overcome unobtainable measurements at the extremes of face mask curvature. General linear model, mixed model, and t tests were used for data analysis. Three hundred seventy-five measurements were used for analysis, with a mean perfusion unit of 299 and pixel validity of 97%. The effect of face mask pressure with and without the silicone liner was readily quantified with significant changes in mean cutaneous blood flow (P face masks. Perfusion decreases with the application of pressure and with silicone. Every participant measured differently in perfusion units; however, consistent perfusion patterns in the face were observed.

Quantitation of stress echocardiography by tissue Doppler and strain rate imaging: a dream come true?

Science.gov (United States)

Galderisi, Maurizio; Mele, Donato; Marino, Paolo Nicola

2005-01-01

Tissue Doppler (TD) is an ultrasound tool providing a quantitative agreement of left ventricular regional myocardial function in different modalities. Spectral pulsed wave (PW) TD, performed online during the examination, measures instantaneous myocardial velocities. By means of color TD, velocity images are digitally stored for subsequent off-line analysis and mean myocardial velocities are measured. An implementation of color TD includes strain rate imaging (SRI), based on post-processing conversion of regional velocities in local myocardial deformation rate (strain rate) and percent deformation (strain). These three modalities have been applied to stress echocardiography for quantitative evaluation of regional left ventricular function and detection of ischemia and viability. They present advantages and limitations. PWTD does not permit the simultaneous assessment of multiple walls and therefore is not compatible with clinical stress echocardiography while it could be used in a laboratory setting. Color TD provides a spatial map of velocity throughout the myocardium but its results are strongly affected by the frame rate. Both color TD and PWTD are also influenced by overall cardiac motion and tethering from adjacent segments and require reference velocity values for interpretation of regional left ventricular function. High frame rate (i.e. > 150 ms) post-processing-derived SRI can potentially overcome these limitations, since measurements of myocardial deformation have not any significant apex-to-base gradient. Preliminary studies have shown encouraging results about the ability of SRI to detect ischemia and viability, in terms of both strain rate changes and/or evidence of post-systolic thickening. SRI is, however, Doppler-dependent and time-consuming. Further technical refinements are needed to improve its application and introduce new ultrasound modalities to overcome the limitations of the Doppler-derived deformation analysis.

Magnetic resonance imaging of the elbow. Part I: Normal anatomy, imaging technique, and osseous abnormalities

International Nuclear Information System (INIS)

Kijowski, Richard; Tuite, Michael; Sanford, Matthew

2004-01-01

Part I of this comprehensive review on magnetic resonance imaging of the elbow discusses normal elbow anatomy and the technical factors involved in obtaining high-quality magnetic resonance images of the elbow. Part I also discusses the role of magnetic resonance imaging in evaluating patients with osseous abnormalities of the elbow. With proper patient positioning and imaging technique, magnetic resonance imaging can yield high-quality multiplanar images which are useful in evaluating the osseous structures of the elbow. Magnetic resonance imaging can detect early osteochondritis dissecans of the capitellum and can be used to evaluate the size, location, stability, and viability of the osteochondritis dissecans fragment. Magnetic resonance imaging can detect early stress injury to the proximal ulna in athletes. Magnetic resonance imaging can detect radiographically occult fractures of the elbow in both children and adults. Magnetic resonance imaging is also useful in children to further evaluate elbow fractures which are detected on plain-film radiographs. (orig.)

Magnetic resonance imaging (MRI)

OpenAIRE

Takavar A

1993-01-01

Basic physical principles of nuclear magnetic resonance imaging (N.M.R.I), a nonionizing medical imaging technique, are described. Principles of NMRI with other conventional imaging methods, ie, isotope scanning, ultrasonography and radiography have been compared. T1 and T2 and spin density (S.D.) factors and different image construction techniques based on their different combinations is discussed and at the end physical properties of some N.M.R images is mentioned.

Laser Doppler Blood Flow Imaging Using a CMOS Imaging Sensor with On-Chip Signal Processing

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Cally Gill

2013-09-01

Full Text Available The first fully integrated 2D CMOS imaging sensor with on-chip signal processing for applications in laser Doppler blood flow (LDBF imaging has been designed and tested. To obtain a space efficient design over 64 × 64 pixels means that standard processing electronics used off-chip cannot be implemented. Therefore the analog signal processing at each pixel is a tailored design for LDBF signals with balanced optimization for signal-to-noise ratio and silicon area. This custom made sensor offers key advantages over conventional sensors, viz. the analog signal processing at the pixel level carries out signal normalization; the AC amplification in combination with an anti-aliasing filter allows analog-to-digital conversion with a low number of bits; low resource implementation of the digital processor enables on-chip processing and the data bottleneck that exists between the detector and processing electronics has been overcome. The sensor demonstrates good agreement with simulation at each design stage. The measured optical performance of the sensor is demonstrated using modulated light signals and in vivo blood flow experiments. Images showing blood flow changes with arterial occlusion and an inflammatory response to a histamine skin-prick demonstrate that the sensor array is capable of detecting blood flow signals from tissue.

Laser doppler blood flow imaging using a CMOS imaging sensor with on-chip signal processing.

Science.gov (United States)

He, Diwei; Nguyen, Hoang C; Hayes-Gill, Barrie R; Zhu, Yiqun; Crowe, John A; Gill, Cally; Clough, Geraldine F; Morgan, Stephen P

2013-09-18

The first fully integrated 2D CMOS imaging sensor with on-chip signal processing for applications in laser Doppler blood flow (LDBF) imaging has been designed and tested. To obtain a space efficient design over 64 × 64 pixels means that standard processing electronics used off-chip cannot be implemented. Therefore the analog signal processing at each pixel is a tailored design for LDBF signals with balanced optimization for signal-to-noise ratio and silicon area. This custom made sensor offers key advantages over conventional sensors, viz. the analog signal processing at the pixel level carries out signal normalization; the AC amplification in combination with an anti-aliasing filter allows analog-to-digital conversion with a low number of bits; low resource implementation of the digital processor enables on-chip processing and the data bottleneck that exists between the detector and processing electronics has been overcome. The sensor demonstrates good agreement with simulation at each design stage. The measured optical performance of the sensor is demonstrated using modulated light signals and in vivo blood flow experiments. Images showing blood flow changes with arterial occlusion and an inflammatory response to a histamine skin-prick demonstrate that the sensor array is capable of detecting blood flow signals from tissue.

Laser Doppler imaging, thermographic imaging, and tissue oxygen saturation measurements detect early skin reactions during breast radiotherapy

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Harrison, David K.; Harrison, Eileen M.; Newton, David J.; Windsor, Phyllis M.

2001-05-01

A range of acute skin reactions, ranging from mild erythema to moist desquamation, can be seen in patients receiving standard fractionated radiotherapy to the breast for conservation therapy of breast carcinoma. In a number of cases these reactions can cause considerable discomfort and seriously affect the patient's quality of life. In previous studies we have used the techniques of laser Doppler imaging, digital thermographic imaging and lightguide spectrophotometry to study oxygen supply and blood flow in inflammatory reactions induced experimentally in forearm skin. The present study is an attempt to use the same techniques to investigate whether any or all of them can detect changes in breast skin very early on in the course of radiotherapy treatment. A further aim of the longer term study is to investigate to what extent these early changes may be able to predict the occurrence later of severe acute or delayed reactions.

Magnetic resonance imaging of the fetal brain.

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Tee, L Mf; Kan, E Yl; Cheung, J Cy; Leung, W C

2016-06-01

This review covers the recent literature on fetal brain magnetic resonance imaging, with emphasis on techniques, advances, common indications, and safety. We conducted a search of MEDLINE for articles published after 2010. The search terms used were "(fetal OR foetal OR fetus OR foetus) AND (MR OR MRI OR [magnetic resonance]) AND (brain OR cerebral)". Consensus statements from major authorities were also included. As a result, 44 relevant articles were included and formed the basis of this review. One major challenge is fetal motion that is largely overcome by ultra-fast sequences. Currently, single-shot fast spin-echo T2-weighted imaging remains the mainstay for motion resistance and anatomical delineation. Recently, a snap-shot inversion recovery sequence has enabled robust T1-weighted images to be obtained, which is previously a challenge for standard gradient-echo acquisitions. Fetal diffusion-weighted imaging, diffusion tensor imaging, and magnetic resonance spectroscopy are also being developed. With multiplanar capabilities, superior contrast resolution and field of view, magnetic resonance imaging does not have the limitations of sonography, and can provide additional important information. Common indications include ventriculomegaly, callosum and posterior fossa abnormalities, and twin complications. There are safety concerns about magnetic resonance-induced heating and acoustic damage but current literature showed no conclusive evidence of deleterious fetal effects. The American College of Radiology guideline states that pregnant patients can be accepted to undergo magnetic resonance imaging at any stage of pregnancy if risk-benefit ratio to patients warrants that the study be performed. Magnetic resonance imaging of the fetal brain is a safe and powerful adjunct to sonography in prenatal diagnosis. It can provide additional information that aids clinical management, prognostication, and counselling.

Magnetic resonance imaging (MRI

Directory of Open Access Journals (Sweden)

Takavar A

1993-04-01

Full Text Available Basic physical principles of nuclear magnetic resonance imaging (N.M.R.I, a nonionizing medical imaging technique, are described. Principles of NMRI with other conventional imaging methods, ie, isotope scanning, ultrasonography and radiography have been compared. T1 and T2 and spin density (S.D. factors and different image construction techniques based on their different combinations is discussed and at the end physical properties of some N.M.R images is mentioned.

Magnetic Resonance Imaging (MRI) -- Head

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Full Text Available ... it is useful to bring that to the attention of the scheduler before the exam and bring ... Image Gallery Magnetic Resonance Imaging (MRI) procedure View full size with caption Pediatric Content Some imaging tests ...

Gold nanorods as a contrast agent for Doppler optical coherence tomography.

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Bo Wang

Full Text Available To investigate gold nanorods (GNRs as a contrast agent to enhance Doppler optical coherence tomography (OCT imaging of the intrascleral aqueous humor outflow.A serial dilution of GNRs was scanned with a spectral-domain OCT device (Bioptigen, Durham, NC to visualize Doppler signal. Doppler measurements using GNRs were validated using a controlled flow system. To demonstrate an application of GNR enhanced Doppler, porcine eyes were perfused at constant pressure with mock aqueous alone or 1.0×10(12 GNR/mL mixed with mock aqueous. Twelve Doppler and volumetric SD-OCT scans were obtained from the limbus in a radial fashion incremented by 30°, forming a circular scan pattern. Volumetric flow was computed by integrating flow inside non-connected vessels throughout all 12 scans around the limbus.At the GNR concentration of 0.7×10(12 GNRs/mL, Doppler signal was present through the entire depth of the testing tube without substantial attenuation. A well-defined laminar flow profile was observed for Doppler images of GNRs flowing through the glass capillary tube. The Doppler OCT measured flow profile was not statistically different from the expected flow profile based upon an autoregressive moving average model, with an error of -0.025 to 0.037 mm/s (p = 0.6435. Cross-sectional slices demonstrated the ability to view anterior chamber outflow ex-vivo using GNR-enhanced Doppler OCT. Doppler volumetric flow measurements were comparable to flow recorded by the perfusion system.GNRs created a measureable Doppler signal within otherwise silent flow fields in OCT Doppler scans. Practical application of this technique was confirmed in a constant pressure ex-vivo aqueous humor outflow model in porcine eyes.

Functional magnetic resonance imaging by visual stimulation

International Nuclear Information System (INIS)

Nishimura, Yukiko; Negoro, Kiyoshi; Morimatsu, Mitsunori; Hashida, Masahiro

1996-01-01

We evaluated functional magnetic resonance images obtained in 8 healthy subjects in response to visual stimulation using a conventional clinical magnetic resonance imaging system with multi-slice spin-echo echo planar imaging. Activation in the visual cortex was clearly demonstrated by the multi-slice experiment with a task-related change in signal intensity. In addition to the primary visual cortex, other areas were also activated by a complicated visual task. Multi-slice spin-echo echo planar imaging offers high temporal resolution and allows the three-dimensional analysis of brain function. Functional magnetic resonance imaging provides a useful noninvasive method of mapping brain function. (author)

Magnetic Resonance Imaging (MRI): Brain (For Parents)

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... Staying Safe Videos for Educators Search English Español Magnetic Resonance Imaging (MRI): Brain KidsHealth / For Parents / Magnetic Resonance Imaging (MRI): Brain What's in this article? What ...

Magnetic Resonance Imaging (MRI) -- Head

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Full Text Available ... As the hydrogen atoms return to their usual alignment, they emit different amounts of energy that vary ... story about radiology? Share your patient story here Images × Image Gallery Magnetic Resonance Imaging (MRI) procedure View ...

Imaging of juvenile spondyloarthritis. Part II: Ultrasonography and magnetic resonance imaging

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Iwona Sudoł-Szopińska

2017-09-01

Full Text Available Juvenile spondyloarthropathies are mainly manifested by symptoms of peripheral arthritis and enthesitis. Early involvement of sacroiliac joints and spine is exceptionally rare in children; this usually happens in adulthood. Conventional radiographs visualize late inflammatory lesions. Early diagnosis is possible with the use of ultrasonography and magnetic resonance imaging. The first part of the article presented classifications and radiographic presentation of juvenile spondyloarthropathies. This part discusses changes seen on ultrasonography and magnetic resonance imaging. In patients with juvenile spondyloarthropathies, these examinations are conducted to diagnose inflammatory lesions in peripheral joints, tendon sheaths, tendons and bursae. Moreover, magnetic resonance also shows subchondral bone marrow edema, which is considered an early sign of inflammation. Ultrasonography and magnetic resonance imaging do not show specific lesions for any rheumatic disease. Nevertheless, they are conducted for early diagnosis, treatment monitoring and identifying complications. This article presents a spectrum of inflammatory changes and discusses the diagnostic value of ultrasonography and magnetic resonance imaging.

Magnetic resonance imaging

International Nuclear Information System (INIS)

Sigal, R.

1988-01-01

This book is an introduction to magnetic resonance imaging (MRI). The basic principles for the interpretation of MR images are developed. The book is divided into five chapters: introduction, tissue, parameters, acquisition parameters, contribution to diagnosis, and practical management of an MR examination. Eight exercises allow the reader to test the knowledge he has acquired. Signal localization and MR artefacts are reviewed in an appendix

Quantitative perfusion imaging in magnetic resonance imaging

International Nuclear Information System (INIS)

Zoellner, F.G.; Gaa, T.; Zimmer, F.; Ong, M.M.; Riffel, P.; Hausmann, D.; Schoenberg, S.O.; Weis, M.

2016-01-01

Magnetic resonance imaging (MRI) is recognized for its superior tissue contrast while being non-invasive and free of ionizing radiation. Due to the development of new scanner hardware and fast imaging techniques during the last decades, access to tissue and organ functions became possible. One of these functional imaging techniques is perfusion imaging with which tissue perfusion and capillary permeability can be determined from dynamic imaging data. Perfusion imaging by MRI can be performed by two approaches, arterial spin labeling (ASL) and dynamic contrast-enhanced (DCE) MRI. While the first method uses magnetically labelled water protons in arterial blood as an endogenous tracer, the latter involves the injection of a contrast agent, usually gadolinium (Gd), as a tracer for calculating hemodynamic parameters. Studies have demonstrated the potential of perfusion MRI for diagnostics and also for therapy monitoring. The utilization and application of perfusion MRI are still restricted to specialized centers, such as university hospitals. A broad application of the technique has not yet been implemented. The MRI perfusion technique is a valuable tool that might come broadly available after implementation of standards on European and international levels. Such efforts are being promoted by the respective professional bodies. (orig.) [de

Role of chelates in magnetic resonance imaging studies

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Tripathi Laxmi

2009-01-01

Full Text Available Imaging studies are tests performed with a variety of techniques that produce pictures of the inside of a patient′s body. Magnetic resonance imaging (MRI is an imaging technique based on the principles of nuclear magnetic resonance. MRI uses a powerful magnetic field, radio waves, and a computer to produce detailed pictures of organs, soft tissues, bone, and virtually all other internal body structures. Chelates have a wide application in such imaging techniques. Chelates in imaging studies are used alone as radioactive agents or conjugated to monoclonal antibodies or to DNA as radioactive agents. Technetium chelates and gadolinium chelates are being widely used as magnetic resonance contrast media.

Prediction of adverse pregnancy outcomes using uterine artery Doppler imaging at 22-24 weeks of pregnancy: A North Indian experience

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Deepti Verma

2016-06-01

Full Text Available Objective: The aim of this study was to assess the predictive value of uterine artery Doppler imaging at 22-24 weeks of gestation for adverse pregnancy outcomes. Materials and Methods: This was a prospective study in which uterine artery Doppler was performed at 22-24 weeks of gestation in 165 pregnant women with singleton pregnancies. A pulsatility index (PI more than 1.45 or bilateral uterine notching was labeled as abnormal Doppler. The pregnancy outcome was assessed in terms of normal outcome, preeclampsia, fetal growth restriction (FGR, low birth weight, spontaneous preterm delivery, oligohydramnios, fetal loss or at least one adverse outcome. Results: Out of 165 patients, 35 (21.2% had abnormal second trimester uterine artery Doppler. In pregnancies that resulted in preeclampsia (PE, (n=21, FGR, (n=21, and low birth weight (n=39, the median uterine artery PI was higher (1.52, 1.41, and 1.27 respectively. In the presence of abnormal Doppler, the risk of PE [OR=10.7, 95% confidence interval (CI: (3.91-29.1; p<0.001], FGR [OR=4.34, 95% CI: (1.62-11.6; p=0.002], low birth weight [OR=6.39, 95% CI: (3.16-12.9; p<0.001] and the risk of at least one obstetric complication [OR=8.73, 95% CI: (3.5-21.3; p<0.001] was significantly high. The positive predictive value of abnormal uterine artery Doppler was highest for preeclampsia (36.84% among all adverse pregnancy outcomes assessed. Conclusion: Uterine artery Doppler ultrasonography at 22-24 weeks of gestation is a significant predictor of at least one adverse pregnancy outcome, with the highest prediction for preeclampsia.

Magnetic resonance imaging in clinically-definite multiple sclerosis

International Nuclear Information System (INIS)

Noakes, J.B.; Herkes, G.K.; Frith, J.A.

1990-01-01

Forty-two patients with clinically-definite multiple sclerosis were examined by magnetic resonance imaging using a 1.5-T instrument. Magnetic resonance imaging detected an abnormality in 90% of patients. In four patients, no lesions were demonstrated. The number, size and site of the lesions by magnetic resonance imaging were compared with the patients' clinical status and other variables. The Kurtzke disability status scale score increased in patients with corpus callosum atrophy, brainstem and basal ganglia lesions, and correlated with the total number of lesions. No correlation was shown between the findings of magnetic resonance imaging and disease duration, age, sex or pattern-reversal visual-evoked potentials. The variety of magnetic resonance images that could be obtained in patients with clinically-definite multiple sclerosis is highlighted. 24 refs., 8 figs., 1 tab

Low field magnetic resonance imaging

Science.gov (United States)

Pines, Alexander; Sakellariou, Dimitrios; Meriles, Carlos A.; Trabesinger, Andreas H.

2010-07-13

A method and system of magnetic resonance imaging does not need a large homogenous field to truncate a gradient field. Spatial information is encoded into the spin magnetization by allowing the magnetization to evolve in a non-truncated gradient field and inducing a set of 180 degree rotations prior to signal acquisition.

Functional Magnetic Resonance Imaging

Science.gov (United States)

Voos, Avery; Pelphrey, Kevin

2013-01-01

Functional magnetic resonance imaging (fMRI), with its excellent spatial resolution and ability to visualize networks of neuroanatomical structures involved in complex information processing, has become the dominant technique for the study of brain function and its development. The accessibility of in-vivo pediatric brain-imaging techniques…

Color Doppler US of the penis

Energy Technology Data Exchange (ETDEWEB)

Bertolotto, Michele (ed.) [Trieste Univ. Ospedale di Cattinara (Italy). Dept. Radiology

2008-07-01

This book provides a comprehensive reference and practical guide on the application of US to penile diseases and conditions. After introductory chapters on technical requirements and penile anatomy, subsequent chapters offer a systematic overview of the diverse applications of color Doppler US. The topics covered include erectile dysfunction, Peyronie's disease, priapism, trauma, tumors, the postoperative penis, inflammation, and fibrosis. Each topic is introduced by a clinical overview with the purpose of clarifying the problems and elucidating what the urologist may expect from color Doppler US. Thereafter, performance of the US study is explained and the pathological anatomy reviewed. High-quality images obtained with high-end US equipment are included. Each chapter also contains a section on the diagnostic information provided by other imaging modalities, and in particular MRI. (orig.)

Nuclear Magnetic Resonance Imaging of Li-ion Battery

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D. Ohno

2010-12-01

Full Text Available Nuclear magnetic resonance (NMR imaging has high sensitivity to proton (1H and lithium (7Li. It is a useful measurement for electrolyte in Li-ion battery. 1H NMR images of lithium ion battery which is composed of LiMn2O4 / LiClO4 + propylene carbonate (PC / Li-metal have been studied. 1H NMR images of electrolyte near cathode material (LiMn2O4 showed anomalous intensity distribution, which was quite inhomogeneous. From NMR images as a function of repetition time (TR, it was concluded that the anomalous intensity distribution was not due to change of relaxation time but an indirect (spatial para-magnetization effect from cathode material. The paramagnetization induced by high magnetic field distorts linearity of magnetic gradient field, leading to apparent intensity variance. This functional image is an easy diagnostic measurement for magnetization of cathode material, which allows the possibility to check uniformity of cathode material and change of magnetization under electrochemical process.

Quantitative Assessment of Synovial Vascularity Using Contrast-Enhanced Power Doppler Ultrasonography: Correlation with Histologic Findings and MR Imaging Findings in Arthritic Rabbit Knee Model

International Nuclear Information System (INIS)

Lee, Sang Hoon; Shin, Myung Jin; Kim, Seong Moon; Kim, Namkug; Suh, Sang Hyun; Suh, Jin Suck

2008-01-01

To validate contrast-enhanced power Doppler ultrasonography (PD US) for the evaluation of synovial vascularity in an arthritic rabbit knee model in correlation with MR and histological findings. Power Doppler ultrasonography was performed for carrageenin-induced arthritic left knee and control right knee of 13 rabbits, first without and then with sonic contrast agent enhancement (Levovist, Schering, Berlin Germany), followed by gadolinium-enhanced MR imaging. Synovial vascularity was quantitatively assessed by calculating the color pixel area in power Doppler sonography using a computer-aided image analysis program and by grading the enhancement on MR images: grade 1, enhancement of knee joint is less than one-third of the area; grade 2, one-third to two-thirds enhancement; and grade 3, more than two-thirds enhancement. Microvessel density (MVD) was measured on slides stained immunohistochemically for CD31 antigen for histological assessment. The mean area of color pixels in PD US changed from 4.37 to 16.42 mm 2 in the arthritic knee after enhancement (p 2 in the control knee (p 0.05). Sonic contrast-enhanced PD US improves the visualization of synovial vascularity and allows quantitative measurement in experimentally induced rabbit arthritic knees

Helium temperature measurements in a hot filament magnetic mirror plasma using high resolution Doppler spectroscopy

Science.gov (United States)

Knott, S.; McCarthy, P. J.; Ruth, A. A.

2016-09-01

Langmuir probe and spectroscopic diagnostics are used to routinely measure electron temperature and density over a wide operating range in a reconfigured Double Plasma device at University College Cork, Ireland. The helium plasma, generated through thermionic emission from a negatively biased tungsten filament, is confined by an axisymmetric magnetic mirror configuration using two stacks of NdFeB permanent magnets, each of length 20 cm and diameter 3 cm placed just outside the 15 mm water cooling jacket enclosing a cylindrical vacuum vessel of internal diameter 25 cm. Plasma light is analysed using a Fourier Transform-type Bruker spectrometer with a highest achievable resolution of 0.08 cm-1 . In the present work, the conventional assumption of room temperature ions in the analysis of Langmuir probe data from low temperature plasmas is examined critically using Doppler spectroscopy of the 468.6 nm He II line. Results for ion temperatures obtained from spectroscopic data for a variety of engineering parameters (discharge voltage, gas pressure and plasma current) will be presented.

SQUID-detected magnetic resonance imaging in microtesla magnetic fields

International Nuclear Information System (INIS)

McDermott, Robert; Kelso, Nathan; Lee, SeungKyun; Moessle, Michael; Mueck, Michael; Myers, Whittier; Haken, Bernard ten; Seton, H.C.; Trabesinger, Andreas H.; Pines, Alex; Clarke, John

2003-01-01

We describe studies of nuclear magnetic resonance (NMR) spectroscopy and magnetic resonance imaging (MRI) of liquid samples at room temperature in microtesla magnetic fields. The nuclear spins are prepolarized in a strong transient field. The magnetic signals generated by the precessing spins, which range in frequency from tens of Hz to several kHz, are detected by a low-transition temperature dc SQUID (Superconducting QUantum Interference Device) coupled to an untuned, superconducting flux transformer configured as an axial gradiometer. The combination of prepolarization and frequency-independent detector sensitivity results in a high signal-to-noise ratio and high spectral resolution (∼1 Hz) even in grossly inhomogeneous magnetic fields. In the NMR experiments, the high spectral resolution enables us to detect the 10-Hz splitting of the spectrum of protons due to their scalar coupling to a 31P nucleus. Furthermore, the broadband detection scheme combined with a non-resonant field-reversal spin echo allows the simultaneous observation of signals from protons and 31P nuclei, even though their NMR resonance frequencies differ by a factor of 2.5. We extend our methodology to MRI in microtesla fields, where the high spectral resolution translates into high spatial resolution. We demonstrate two-dimensional images of a mineral oil phantom and slices of peppers, with a spatial resolution of about 1 mm. We also image an intact pepper using slice selection, again with 1-mm resolution. In further experiments we demonstrate T1-contrast imaging of a water phantom, some parts of which were doped with a paramagnetic salt to reduce the longitudinal relaxation time T1. Possible applications of this MRI technique include screening for tumors and integration with existing multichannel SQUID systems for brain imaging

Reducing Field Distortion in Magnetic Resonance Imaging

Science.gov (United States)

Eom, Byeong Ho; Penanen, Konstantin; Hahn, Inseob

2010-01-01

A concept for a magnetic resonance imaging (MRI) system that would utilize a relatively weak magnetic field provides for several design features that differ significantly from the corresponding features of conventional MRI systems. Notable among these features are a magnetic-field configuration that reduces (relative to the conventional configuration) distortion and blurring of the image, the use of a superconducting quantum interference device (SQUID) magnetometer as the detector, and an imaging procedure suited for the unconventional field configuration and sensor. In a typical application of MRI, a radio-frequency pulse is used to excite precession of the magnetic moments of protons in an applied magnetic field, and the decaying precession is detected for a short time following the pulse. The precession occurs at a resonance frequency proportional to the strengths of the magnetic field and the proton magnetic moment. The magnetic field is configured to vary with position in a known way; hence, by virtue of the aforesaid proportionality, the resonance frequency varies with position in a known way. In other words, position is encoded as resonance frequency. MRI using magnetic fields weaker than those of conventional MRI offers several advantages, including cheaper and smaller equipment, greater compatibility with metallic objects, and higher image quality because of low susceptibility distortion and enhanced spin-lattice-relaxation- time contrast. SQUID MRI is being developed into a practical MRI method for applied magnetic flux densities of the order of only 100 T

Comparison of magnetic resonance imaging and Laser Doppler Anemometry velocity measurements downstream of replacement heart valves: implications for in vivo assessment of prosthetic valve function.

Science.gov (United States)

Fontaine, A A; Heinrich, R S; Walker, P G; Pedersen, E M; Scheidegger, M B; Boesiger, P; Walton, S P; Yoganathan, A P

1996-01-01

The non-invasive, in-vivo assessment of prosthetic valve function is compromised by the lack of accurate measurements of the transvalvular flow fields or hemodynamics by current techniques. Short echo time magnetic resonance imaging (MRI) may provide a method for the non-invasive, in vivo assessment of prosthetic valve function by accurately measuring changes in the transvalvular flow fields associated with normal and dysfunctional prosthetic valves. The objectives of these in vitro experiments were to investigate the potential for using MRI as a tool to measure the complex flow fields distal to replacement heart valves, and to assess the accuracy of MRI velocity measurements by comparison with Laser Doppler Anemometry (LDA), a gold standard. The velocity fields downstream of tilting disc, bileaflet, ball and cage, and pericardial tissue valves were measured using both three-component LDA and MRI phase velocity encoding under a steady flow rate of 22.8 l/min, simulating peak systolic flow. The valves were tested under normal and stenotic conditions to assess the MRI capabilities under a wide range of local flow conditions, velocities and turbulence levels. A new short echo time MRI technique (FAcE), which allowed velocity measurements in stenotic jets with high turbulence, was tested. Good overall agreement was obtained between the MRI velocity measurements and the LDA data. The MRI velocity measurements adequately reproduced the spatial structure of the flow fields. In most cases peak velocities were accurately measured to within 15%. The results indicate that the FAcE MRI method has the potential to be used as a diagnostic tool to assess prosthetic valve function.

Magnetic Resonance Imaging (MRI) -- Head

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Full Text Available ... for Brain Tumors Radiation Therapy for Head and Neck Cancer Others : American Stroke Association National Stroke Association ... MRA) Magnetic Resonance, Functional (fMRI) - Brain Head and Neck Cancer Treatment Brain Tumor Treatment Magnetic Resonance Imaging ( ...

Generation of nuclear magnetic resonance images

International Nuclear Information System (INIS)

Beckmann, N.X.

1986-01-01

Two generation techniques of nuclear magnetic resonance images, the retro-projection and the direct transformation method are studied these techniques are based on the acquisition of NMR signals which phases and frequency components are codified in space by application of magnetic field gradients. The construction of magnet coils is discussed, in particular a suitable magnet geometry with polar pieces and air gap. The obtention of image contrast by T1 and T2 relaxation times reconstructed from generated signals using sequences such as spin-echo, inversion-recovery and stimulated echo, is discussed. The mathematical formalism of matrix solution for Bloch equations is also presented. (M.C.K.)

Doppler-Zeeman Mapping of the Rapidly Rotating Magnetic CP Star HD37776

Science.gov (United States)

Khokhlova, V. L.; Vasilchenko, D. V.; Stepanov, V. V.; Romanyuk, I. I.

2000-03-01

We present the results of our analysis of magnetic-field configuration and abundance anomalies on the surface of the rapidly rotating, chemically peculiar helium-strong variable B2 V star HD37776 with unresolved Zeeman components of spectral lines. Simultaneous inversion of the observed Stokes I and V profiles, which realizes the method of Doppler-Zeeman mapping (Vasilchenko et al. 1996), has been applied for the first time. Spectroscopic observations were carried out with the Main stellar spectrograph of the 6-m Special Astrophysical Observatory telescope equipped with a Zeeman analyzer and a CCD array, which allowed spectra in right- and left-hand circularly polarized light to be taken simultaneously at a signal-to-noise ratio S/N > 200 (Romanyuk et al. 1999). The profile width of winged spectral lines (reaching 5 A) is determined by Zeeman line splitting; however, the observed Zeeman components are blurred and unresolved because of the rapid stellar rotation. When solving the inverse problem, we sought for the magnetic-field configuration in the form of a combination of arbitrarily oriented dipole, quadrupole, and octupole placed at the stellar center. The observed Stokes I and V profiles for eight spectral lines of He, OII, AlIII, SiIII, and FeIII averaged over the visible stellar surface were used as input data. We constructed a model of the magnetic field from the condition of coincidence of magnetic maps obtained from different lines of different chemical elements and from the condition of a minimum profile residual. This model is a combination of centered coaxial dipole and quadrupole with the dominant quadrupole component at 30 deg < i < 50 deg, beta = 40 deg, and a maximum surface field strength H_s = 60 kG. A comparison of our abundance maps with the field configuration shows that the He concentration is at a maximum in the regions of maximum radial field, while the maximum concentrations of O, Al, Si, and Fe coincide with the regions of maximum

Magnetic resonance imaging of infectious myositis

Energy Technology Data Exchange (ETDEWEB)

Yun, Ji Young; Kim, Jee Young; Kim, Sang Heum; Jung, Youn Ju; Cha, Eun Suk; Park, Joung Mi; Park, Young Ha [The Catholic Univ., College of Medicine, Suwon (Korea, Republic of)

1998-09-01

To describe the findings of magnetic resonance imaging in infectious myositis and to determine their value for differentiation between ruberculous and bacterial myositis. Magnetic resonance images of ten proven cases of infectious myositis (five tuberculous and five bacterial) were retrospectively reviewed in the light of clinical and laboratory findings. On the basis of magnetic resonance images, signal intensity of the mass, the presence or absence of an abscess, signal intensity of the peripheral wall, patterns of contrast enhancement, and associated findings were evaluated. Compared with those of bacterial myositis, the symptoms of tuberculous myositis lasted longer but there were no difinite local inflammatory signs. In three of five cases of bacterial myositis there were specific medical records;trauma in two cases and systemic lupus erythematosus in one. All tuberculous myositis cases involved a single muscle, but bacterial myositis affected multipe muscles in three cases(60%). All but one case showed a mass in the involved muscles. In one bacterial case, there was diffuse swelling in the involved muscle. On T1-weighted images, eight infectious cases showed low signal intensity;two, of the bactrerial type, showed subtle increased signal intensity. all cases demonstrated high signal intensity on t2-weighted images. The signal intensity of peripheral wall was slightly increased on T1-weighted images, but low on T2-weighted. In four cases there was associated cellulitis, and in one case each, adjacent joint effusion and deep vein thrombosis were seen. After gadolinium infusion, peripheral rim enhancement was noted in nine cases and heterogeneous enhancement in one. After magnetic resonance imaging of infectious myositis, the characteristic finding was an abscessed lesion, with the peripheral wall showing high signal intensity on T1-weighted images and low signal intensity on T2 weighted. Although we found it difficult to differentiate bacterial from tuberculous

Magnetic resonance imaging of infectious myositis

International Nuclear Information System (INIS)

Yun, Ji Young; Kim, Jee Young; Kim, Sang Heum; Jung, Youn Ju; Cha, Eun Suk; Park, Joung Mi; Park, Young Ha

1998-01-01

To describe the findings of magnetic resonance imaging in infectious myositis and to determine their value for differentiation between ruberculous and bacterial myositis. Magnetic resonance images of ten proven cases of infectious myositis (five tuberculous and five bacterial) were retrospectively reviewed in the light of clinical and laboratory findings. On the basis of magnetic resonance images, signal intensity of the mass, the presence or absence of an abscess, signal intensity of the peripheral wall, patterns of contrast enhancement, and associated findings were evaluated. Compared with those of bacterial myositis, the symptoms of tuberculous myositis lasted longer but there were no difinite local inflammatory signs. In three of five cases of bacterial myositis there were specific medical records;trauma in two cases and systemic lupus erythematosus in one. All tuberculous myositis cases involved a single muscle, but bacterial myositis affected multipe muscles in three cases(60%). All but one case showed a mass in the involved muscles. In one bacterial case, there was diffuse swelling in the involved muscle. On T1-weighted images, eight infectious cases showed low signal intensity;two, of the bactrerial type, showed subtle increased signal intensity. all cases demonstrated high signal intensity on t2-weighted images. The signal intensity of peripheral wall was slightly increased on T1-weighted images, but low on T2-weighted. In four cases there was associated cellulitis, and in one case each, adjacent joint effusion and deep vein thrombosis were seen. After gadolinium infusion, peripheral rim enhancement was noted in nine cases and heterogeneous enhancement in one. After magnetic resonance imaging of infectious myositis, the characteristic finding was an abscessed lesion, with the peripheral wall showing high signal intensity on T1-weighted images and low signal intensity on T2 weighted. Although we found it difficult to differentiate bacterial from tuberculous

76 FR 58281 - Magnetic Resonance Imaging Safety; Public Workshop

Science.gov (United States)

2011-09-20

...] Magnetic Resonance Imaging Safety; Public Workshop AGENCY: Food and Drug Administration, HHS. ACTION... announcing a public workshop entitled: ``Magnetic Resonance Imaging (MRI) Safety Public Workshop.'' The purpose of the public workshop is to discuss factors affecting the safe use of magnetic resonance imaging...

Functional magnetic resonance imaging of the primary motor cortex ...

Indian Academy of Sciences (India)

Unknown

Abbreviations used: BOLD, Blood oxygenation level dependent; CBF, cerebral blood flow; fMRI, functional magnetic resonance imaging; EPI, eco-planar imaging; FOV, field of view; MRI, Magnetic resonance imaging; MRS, magnetic resonance spectroscopy;. PET, position emission tomography; rCBF, regional cerebral ...

Developments in target micro-Doppler signatures analysis: radar imaging, ultrasound and through-the-wall radar

OpenAIRE

Clemente, C.; Balleri, A.; Woodbridge, K.; Soraghan, J. J.

2013-01-01

Target motions, other than the main bulk translation of the target, induce Doppler modulations around the main Doppler shift that form what is commonly called a target micro-Doppler signature. Radar micro-Doppler signatures are generally both target and action speci c and hence can be used to classify and recognise targets as well as to identify possible threats. In recent years, research into the use of micro-Doppler signatures for target classi cation to address many defence and security ch...

Children's (Pediatric) Magnetic Resonance Imaging

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Full Text Available ... work? Unlike conventional x-ray examinations and computed tomography (CT) scans, MRI does not utilize ionizing radiation. Instead, ... Angiography Magnetic Resonance, Functional (fMRI) - Brain Children's (Pediatric) CT (Computed Tomography) Magnetic Resonance Imaging (MRI) Safety Contrast Materials Children ...

Susceptibility effects in nuclear magnetic resonance imaging

International Nuclear Information System (INIS)

Ziener, Christian Herbert

2008-01-01

The properties of dephasing and the resulting relaxation of the magnetization are the basic principle on which all magnetic resonance imaging methods are based. The signal obtained from the gyrating spins is essentially determined by the properties of the considered tissue. Especially the susceptibility differences caused by magnetized materials (for example, deoxygenated blood, BOLD-effect) or magnetic nanoparticles are becoming more important for biomedical imaging. In the present work, the influence of such field inhomogeneities on the NMR-signal is analyzed. (orig.)

Musculoskeletal applications of magnetic resonance imaging: Council on Scientific Affairs

International Nuclear Information System (INIS)

Harms, S.E.; Fisher, C.F.; Fulmer, J.M.

1989-01-01

Magnetic resonance imaging provides superior contrast, resolution, and multiplanar imaging capability, allowing excellent definition of soft-tissue and bone marrow abnormalities. For these reasons, magnetic resonance imaging has become a major diagnostic imaging method for the evaluation of many musculoskeletal disorders. The applications of magnetic resonance imaging for musculoskeletal diagnosis are summarized and examples of common clinical situations are given. General guidelines are suggested for the musculoskeletal applications of magnetic resonance imaging

Applications of Doppler in the first trimester

International Nuclear Information System (INIS)

Taylor, K.J.W.; Ramirez, B.; Grannum, P.

1986-01-01

Fifty patients have been studied by duplex Doppler US imaging in the first trimester. In normal gestations, luteal flow, characterized by a low pulsatility index (PI), can be seen in at least one ovary. Failure to detect luteal flow indicates a nonviable pregnancy. Six ectopic pregnancies demonstrated luteal flow and extrauterine heartbeat, detected by Doppler US. High PI values in the uterine artery are seen in the first trimester. Low PI values in the uterine arteries were found in patients with trophoblastic disease

Imaging by magnetic resonance

International Nuclear Information System (INIS)

Duroure, J.F.; Serpolay, H.; Vallens, D.

1995-01-01

Here are described the advanced technology for nuclear magnetic resonance imaging: reduction of acquisition times, and rebuilding times, images quality improvement. The tendency is to open the machines at low and middle field, on a market being at 10% of NMR I sales, with economical, scientifical and ergonomic reasons broadly developed by constructors

Doppler Spectrum-Based NRCS Estimation Method for Low-Scattering Areas in Ocean SAR Images

Directory of Open Access Journals (Sweden)

Hui Meng

2017-02-01

Full Text Available The image intensities of low-backscattering areas in synthetic aperture radar (SAR images are often seriously contaminated by the system noise floor and azimuthal ambiguity signal from adjacent high-backscattering areas. Hence, the image intensity of low-backscattering areas does not correctly reflect the backscattering intensity, which causes confusion in subsequent image processing or interpretation. In this paper, a method is proposed to estimate the normalized radar cross-section (NRCS of low-backscattering area by utilizing the differences between noise, azimuthal ambiguity, and signal in the Doppler frequency domain of single-look SAR images; the aim is to eliminate the effect of system noise and azimuthal ambiguity. Analysis shows that, for a spaceborne SAR with a noise equivalent sigma zero (NESZ of −25 dB and a single-look pixel of 8 m × 5 m, the NRCS-estimation precision of this method can reach −38 dB at a resolution of 96 m × 100 m. Three examples are given to validate the advantages of this method in estimating the low NRCS and the filtering of the azimuthal ambiguity.

Contrast-enhanced power Doppler US of hepatocellular carcinomas: Quantitative analysis

International Nuclear Information System (INIS)

Kim, Ah Young; Choi, Byung Ihn; Kim, Tae Kyoung; Lee, Kyoung Ho; Han, Joon Koo

1999-01-01

To determine peak time and duration of contrast enhancement of nodular hepatocellular carcinoma (HCC) on contrast-enhancement power Doppler ultrasound (US) with Levovist by quantitative analysis. Twenty eight patients with nodular HCC were prospectively evaluated with power Doppler US by one examiner. Serial images were obtained before and after injection of 300 mg/mL US contrast agent (SH U 508 A, Levovist, Schering) with the injection rate of 0.2 mL/sec. Power Doppler signals on obtained digital images were quantified using 'Ultrasound Imaging Tool Version 1.0' (Seoul, Korea). The grade, peak time and duration of contrast enhancement of the tumors were analyzed. For nodular HCCs, mean peak enhancement time was 60 seconds after injection of Levovist (mean enhanced area 41.6 ± 28.6 %). These tumoral enhancement decreased from 90 seconds and returned to near baseline state at 5 minutes after injection of Levovist. Maximum enhanced areas (%) were variable at a range of 8-98.5% and mean maximum enhanced area was 46.4 ± 28.6%. On contrast-enhanced power Doppler US with Levovist, nodular HCCs showed peak contrast enhancement (41.6± 28.6) at 60 seconds after injection of contrast agent. This tumoral enhancement nearly disappeared at 5 minutes after injection of contrast agent.

Pulse sequences for contrast-enhanced magnetic resonance imaging

International Nuclear Information System (INIS)

Graves, Martin J.

2007-01-01

The theory and application of magnetic resonance imaging (MRI) pulse sequences following the administration of an exogenous contrast agent are discussed. Pulse sequences are categorised according to the contrast agent mechanism: changes in proton density, relaxivity, magnetic susceptibility and resonant frequency shift. Applications in morphological imaging, magnetic resonance angiography, dynamic imaging and cell labelling are described. The importance of optimising the pulse sequence for each application is emphasised

Magnetic Resonance Imaging (MRI) -- Head

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Full Text Available Toggle navigation Test/Treatment Patient Type Screening/Wellness Disease/Condition Safety En Español More Info Images/Videos About Us News Physician Resources Professions Site Index A-Z Magnetic Resonance Imaging (MRI) - ...

Prognostic Value of Cardiac Time Intervals by Tissue Doppler Imaging M-Mode in Patients With Acute ST-Segment-Elevation Myocardial Infarction Treated With Primary Percutaneous Coronary Intervention

DEFF Research Database (Denmark)

Biering-Sørensen, Tor; Mogelvang, Rasmus; Søgaard, Peter

2013-01-01

Background- Color tissue Doppler imaging M-mode through the mitral leaflet is an easy and precise method to estimate all cardiac time intervals from 1 cardiac cycle and thereby obtain the myocardial performance index (MPI). However, the prognostic value of the cardiac time intervals and the MPI...... assessed by color tissue Doppler imaging M-mode through the mitral leaflet in patients with ST-segment-elevation myocardial infarction (MI) is unknown. Methods and Results- In total, 391 patients were admitted with an ST-segment-elevation MI, treated with primary percutaneous coronary intervention...

The Role of Color Doppler Ultrasonography in Characterization of Thyroid Tumors

International Nuclear Information System (INIS)

Kim, Hee Soo; Jeon, Pyong; Won, Jong Yoon; Na, Jae Beom; Lee, Hyang Mee; Yoo, Hyung Sik; Lee, Jong Tae; Park, Jeong Soo; Cho, Nam Hoon

1995-01-01

To assess the usefulness of color Doppler ultrasonography in the characterization of thyroid tumors, surgically proven 88 nodules in 85 patients were evaluated. Using 10 MHz linear array transducer, gray scale images were initially evaluated. Then, distribution pattern of color signals (marginal, intra-tumoral, mixed) and graded internal vascularity according to morphology of color signal (0:absence of internal signal, 1: spotty, 2: linear,3: branching) were observed on color doppler imaging. Pulsed doppler waves were analyzed with parameters including peak systolic velocity(PSV), resistive index(RI), and pulsatile index(PI). Significantly larger numbers of intra-tumoral type, 20 cases(62.5%), were observed in malignant nodules, whereas mixed forms were predominant in benign group, 37 cases (66%) In graded internal vascularity, malignant nodules tended to have grade 2 or 3 signals, whereas benign nodules tended to have grade 0 or 1 signals. Spectral wave analysis show no significant difference in the value of PSV, RI, and PI between malignancy and benignity group. In conclusion, color Doppler imaging has a potential role in the characterization of thyroid nodules as a supportive method for gray scale diagnosis

Bone surface enhancement in ultrasound images using a new Doppler-based acquisition/processing method

Science.gov (United States)

Yang, Xu; Tang, Songyuan; Tasciotti, Ennio; Righetti, Raffaella

2018-01-01

Ultrasound (US) imaging has long been considered as a potential aid in orthopedic surgeries. US technologies are safe, portable and do not use radiations. This would make them a desirable tool for real-time assessment of fractures and to monitor fracture healing. However, image quality of US imaging methods in bone applications is limited by speckle, attenuation, shadow, multiple reflections and other imaging artifacts. While bone surfaces typically appear in US images as somewhat ‘brighter’ than soft tissue, they are often not easily distinguishable from the surrounding tissue. Therefore, US imaging methods aimed at segmenting bone surfaces need enhancement in image contrast prior to segmentation to improve the quality of the detected bone surface. In this paper, we present a novel acquisition/processing technique for bone surface enhancement in US images. Inspired by elastography and Doppler imaging methods, this technique takes advantage of the difference between the mechanical and acoustic properties of bones and those of soft tissues to make the bone surface more easily distinguishable in US images. The objective of this technique is to facilitate US-based bone segmentation methods and improve the accuracy of their outcomes. The newly proposed technique is tested both in in vitro and in vivo experiments. The results of these preliminary experiments suggest that the use of the proposed technique has the potential to significantly enhance the detectability of bone surfaces in noisy ultrasound images.

Bone surface enhancement in ultrasound images using a new Doppler-based acquisition/processing method.

Science.gov (United States)

Yang, Xu; Tang, Songyuan; Tasciotti, Ennio; Righetti, Raffaella

2018-01-17

Ultrasound (US) imaging has long been considered as a potential aid in orthopedic surgeries. US technologies are safe, portable and do not use radiations. This would make them a desirable tool for real-time assessment of fractures and to monitor fracture healing. However, image quality of US imaging methods in bone applications is limited by speckle, attenuation, shadow, multiple reflections and other imaging artifacts. While bone surfaces typically appear in US images as somewhat 'brighter' than soft tissue, they are often not easily distinguishable from the surrounding tissue. Therefore, US imaging methods aimed at segmenting bone surfaces need enhancement in image contrast prior to segmentation to improve the quality of the detected bone surface. In this paper, we present a novel acquisition/processing technique for bone surface enhancement in US images. Inspired by elastography and Doppler imaging methods, this technique takes advantage of the difference between the mechanical and acoustic properties of bones and those of soft tissues to make the bone surface more easily distinguishable in US images. The objective of this technique is to facilitate US-based bone segmentation methods and improve the accuracy of their outcomes. The newly proposed technique is tested both in in vitro and in vivo experiments. The results of these preliminary experiments suggest that the use of the proposed technique has the potential to significantly enhance the detectability of bone surfaces in noisy ultrasound images.

Magnetic resonance imaging- physical principles and clinical application

International Nuclear Information System (INIS)

Tavri, Omprakash J.

1996-01-01

The advances in equipment and knowledge related to radiology are occurring at an astonishingly rapid rate. On November 8, 1895, William Conrad Roentgen discovered x-rays. In 1972, Godfrey Hounsfield and George Ambrose introduced computec tomography at a meeting of the British Institute of Radiology. In the same year, Paul Lauterbur published the idea of spatially resolving nuclear magnetic resonance samples, naming it zeugmatography. In 1977, Waldo Hinshaw and co-workers published a magnetic resonance image of a human hand and wrist, and by 1981 several centres were obtaining clinical magnetic resonance (MR) images. In a very short time, magnetic resonance imaging (MRI) has gained acceptance as a clinically useful imaging tool. (author)

Children's (Pediatric) Magnetic Resonance Imaging

Medline Plus

Full Text Available ... it is useful to bring that to the attention of the technologist or scheduler before the exam. ... patient for magnetic resonance imaging (MRI) exam. View full size with caption Pediatric Content Some imaging tests ...

Current recommendations for the study of carotid stenosis by doppler ultrasound and other imaging techniques

International Nuclear Information System (INIS)

Perez Matamoros, Angelica

2012-01-01

Ischemic cerebrovascular disease has been one of the most frequent causes of death from chronic disease, as well as cause of long-term disabilities, in both the United States, and in Latin American countries during recent years. It is therefore, important to know about it. An updated review of international recommendations to the Costa Rican health system is performed for carotid imaging study in patients at risk of accidents and ischemic cerebrovascular disease; with special emphasis on carotid Doppler ultrasonography, due to its wide availability in the medical field Costa Rican. Furthermore, certain relevant concepts of other imaging techniques currently available are listed to determine the appropriate choice of each method according to the individual patient's condition, such as conventional angiography and tomographic angiography [es

Multidimensionally encoded magnetic resonance imaging.

Science.gov (United States)

Lin, Fa-Hsuan

2013-07-01

Magnetic resonance imaging (MRI) typically achieves spatial encoding by measuring the projection of a q-dimensional object over q-dimensional spatial bases created by linear spatial encoding magnetic fields (SEMs). Recently, imaging strategies using nonlinear SEMs have demonstrated potential advantages for reconstructing images with higher spatiotemporal resolution and reducing peripheral nerve stimulation. In practice, nonlinear SEMs and linear SEMs can be used jointly to further improve the image reconstruction performance. Here, we propose the multidimensionally encoded (MDE) MRI to map a q-dimensional object onto a p-dimensional encoding space where p > q. MDE MRI is a theoretical framework linking imaging strategies using linear and nonlinear SEMs. Using a system of eight surface SEM coils with an eight-channel radiofrequency coil array, we demonstrate the five-dimensional MDE MRI for a two-dimensional object as a further generalization of PatLoc imaging and O-space imaging. We also present a method of optimizing spatial bases in MDE MRI. Results show that MDE MRI with a higher dimensional encoding space can reconstruct images more efficiently and with a smaller reconstruction error when the k-space sampling distribution and the number of samples are controlled. Copyright © 2012 Wiley Periodicals, Inc.

Children's (Pediatric) Magnetic Resonance Imaging

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Full Text Available ... As the hydrogen atoms return to their usual alignment, they emit different amounts of energy that vary ... story about radiology? Share your patient story here Images × Image Gallery Radiologist prepping patient for magnetic resonance ...

Automated synovium segmentation in doppler ultrasound images for rheumatoid arthritis assessment

Science.gov (United States)

Yeung, Pak-Hei; Tan, York-Kiat; Xu, Shuoyu

2018-02-01

We need better clinical tools to improve monitoring of synovitis, synovial inflammation in the joints, in rheumatoid arthritis (RA) assessment. Given its economical, safe and fast characteristics, ultrasound (US) especially Doppler ultrasound is frequently used. However, manual scoring of synovitis in US images is subjective and prone to observer variations. In this study, we propose a new and robust method for automated synovium segmentation in the commonly affected joints, i.e. metacarpophalangeal (MCP) and metatarsophalangeal (MTP) joints, which would facilitate automation in quantitative RA assessment. The bone contour in the US image is firstly detected based on a modified dynamic programming method, incorporating angular information for detecting curved bone surface and using image fuzzification to identify missing bone structure. K-means clustering is then performed to initialize potential synovium areas by utilizing the identified bone contour as boundary reference. After excluding invalid candidate regions, the final segmented synovium is identified by reconnecting remaining candidate regions using level set evolution. 15 MCP and 15 MTP US images were analyzed in this study. For each image, segmentations by our proposed method as well as two sets of annotations performed by an experienced clinician at different time-points were acquired. Dice's coefficient is 0.77+/-0.12 between the two sets of annotations. Similar Dice's coefficients are achieved between automated segmentation and either the first set of annotations (0.76+/-0.12) or the second set of annotations (0.75+/-0.11), with no significant difference (P = 0.77). These results verify that the accuracy of segmentation by our proposed method and by clinician is comparable. Therefore, reliable synovium identification can be made by our proposed method.

The Contribution of Three-Dimensional Power Doppler Imaging in the Preoperative Assessment of Breast Tumors: A Preliminary Report

Directory of Open Access Journals (Sweden)

K. Kalmantis

2009-01-01

Methods. One hundred and twenty five women with clinically or mammographically suspicious findings were referred for 3D Power Doppler ultrasound prior to surgery. Histological diagnosis was conducted after surgery and compared with ultrasound findings. Sonographic criteria used for breast cancer diagnosis were based on a system that included morphological characteristics and criteria of the vascular pattern of a breast mass by Power Doppler imaging. Results. Seventy-two lesions were histopathologically diagnosed as benign and 53 tumors as malignant. Three-dimensional ultrasound identified 49 out of 53 histologically confirmed breast cancers resulting in a sensitivity of 92.4% and a specificity of 86.1% in diagnosing breast malignancy (PPV: 0.83, NPV:0.94. Conclusions. 3D ultrasonography is a valuable tool in identifying preoperatively the possibility of a tumor to be malignant.

Shimming a superconducting nuclear-magnetic-resonance imaging magnet with steel

International Nuclear Information System (INIS)

Hoult, D.I.; Lee, D.

1985-01-01

Using a recently published paper as a basis, the magnetic field produced by steel bars inserted in a superconducting NMR imaging magnet is analyzed in a spherically harmonic basis set. A description is then given of how such bars were used to improve the homogeneity of the field within the magnet's imaging volume from 1.2 parts per thousand to about 10 ppm. The poor homogeneity was caused by the magnet's being placed in a steel-laden environment, a situation normally shunned by investigators, and it is the author's contention that the results obtained abrogate the main objection to NMR equipment's being installed in an ordinary hospital building. To facilitate the latter, the equations developed may also be used to estimate, prior to installation, the effects of the proposed environment on field homogeneity

Combined preclinical magnetic particle imaging and magnetic resonance imaging. Initial results in mice

International Nuclear Information System (INIS)

Kaul, M.G.; Mummert, T.; Jung, C.; Raabe, N.; Ittrich, H.; Adam, G.; Heinen, U.; Reitmeier, A.

2015-01-01

Magnetic particle imaging (MPI) is a new radiologic imaging modality. For the first time, a commercial preclinical scanner is installed. The goal of this study was to establish a workflow between MPI and magnetic resonance imaging (MRI) scanners for a complete in vivo examination of a mouse and to generate the first co-registered in vivo MR-MP images. The in vivo examination of five mice were performed on a preclinical MPI scanner and a 7 Tesla preclinical MRI system. MRI measurements were used for anatomical referencing and validation of the injection of superparamagnetic iron oxide (SPIO) particles during a dynamic MPI scan. We extracted MPI data of the injection phase and co-registered it with MRI data. A workflow process for a combined in vivo MRI and MPI examination was established. A successful injection of ferucarbotran was proven in MPI and MRI. MR-MPI co-registration allocated the SPIOs in the inferior vena cava and the heart during and shortly after the injection. The acquisition of preclinical MPI and MRI data is feasible and allows the combined analysis of MR-MPI information.

Combined preclinical magnetic particle imaging and magnetic resonance imaging. Initial results in mice

Energy Technology Data Exchange (ETDEWEB)

Kaul, M.G.; Mummert, T.; Jung, C.; Raabe, N.; Ittrich, H.; Adam, G. [University Medical Center Hamburg-Eppendorf, Hamburg (Germany). Dept. of Diagnostic and Interventional Radiology; Weber, O. [Philips Medical Systems DMC GmbH, Hamburg (Germany); Heinen, U. [Bruker BioSpin MRI GmbH, Ettlingen (Germany); Reitmeier, A. [Medical Center Hamburg-Eppendorf, Hamburg (Germany). Animal Facility; Knopp, T. [University Medical Center Hamburg-Eppendorf, Hamburg (Germany). Dept. of Diagnostic and Interventional Radiology; Hamburg University of Technology, Hamburg (Germany)

2015-05-15

Magnetic particle imaging (MPI) is a new radiologic imaging modality. For the first time, a commercial preclinical scanner is installed. The goal of this study was to establish a workflow between MPI and magnetic resonance imaging (MRI) scanners for a complete in vivo examination of a mouse and to generate the first co-registered in vivo MR-MP images. The in vivo examination of five mice were performed on a preclinical MPI scanner and a 7 Tesla preclinical MRI system. MRI measurements were used for anatomical referencing and validation of the injection of superparamagnetic iron oxide (SPIO) particles during a dynamic MPI scan. We extracted MPI data of the injection phase and co-registered it with MRI data. A workflow process for a combined in vivo MRI and MPI examination was established. A successful injection of ferucarbotran was proven in MPI and MRI. MR-MPI co-registration allocated the SPIOs in the inferior vena cava and the heart during and shortly after the injection. The acquisition of preclinical MPI and MRI data is feasible and allows the combined analysis of MR-MPI information.

Magnetic resonance imaging: hazard, risk and safety

International Nuclear Information System (INIS)

Narayan, Pradeep; Suri, S.; Singh, P.

2001-01-01

The hazard and risk associated with magnetic resonance imaging is a matter of concern. In 1982, the Food and Drug Administration (FDA), USA issued guidelines to Hospital's Investigational Review Board (IRBs) in 'Guidelines for Evaluating Electromagnetic Exposure Risks for Trials of Clinical Nuclear Magnetic Resonance (NMR)'. In 1997, the Berufsgenossenschaft (BG), professional association for precision engineering and electronics of Germany, in their preliminary proposal for safety limits extended their concerns on static magnetic field. Owing to both time varying and static magnetic fields applied in Magnetic Resonance Imaging (MRI) this became of immediate concern to user community to assess the potential hazard and risk associated with the NMR system

Magnetic resonance imaging by using nano-magnetic particles

Energy Technology Data Exchange (ETDEWEB)

Shokrollahi, H., E-mail: Shokrollahi@sutech.ac.ir [Electroceramics Group, Department of Materials Science and Engineering, Shiraz University of Technology, Shiraz (Iran, Islamic Republic of); Khorramdin, A. [Electroceramics Group, Department of Materials Science and Engineering, Shiraz University of Technology, Shiraz (Iran, Islamic Republic of); Isapour, Gh. [Department of Materials and Engineering, Hakim Sabzevari University (Iran, Islamic Republic of)

2014-11-15

Magnetism and magnetic materials play a major role in various biological applications, such as magnetic bioseparation, magnetic resonance imaging (MRI), hyperthermia treatment of cancer and drug delivery. Among these techniques, MRI is a powerful method not only for diagnostic radiology but also for therapeutic medicine that utilizes a magnetic field and radio waves. Recently, this technique has contributed greatly to the promotion of the human quality life. Thus, this paper presents a short review of the physical principles and recent advances of MRI, as well as providing a summary of the synthesis methods and properties of contrast agents, like different core materials and surfactants. - Highlights: • This paper studies the physics of MRI as a powerful diagnostic technique. • MRI uses the differentiation between healthy and pathological tissues. • The relaxation times can be shortened by the use of a magnetic contrast agent. • The magnetic nanoparticles act as contrast agents, helping to increase the resolution. • Different synthesis methods can influence the magnetic resonance behavior.

Magnetic Resonance Imaging (MRI): Lumbar Spine (For Parents)

Science.gov (United States)

... Staying Safe Videos for Educators Search English Español Magnetic Resonance Imaging (MRI): Lumbar Spine KidsHealth / For Parents / Magnetic Resonance Imaging (MRI): Lumbar Spine What's in this article? ...

A variable torque motor compatible with magnetic resonance imaging.

Science.gov (United States)

Roeck, W W; Ha, S-H; Farmaka, S; Nalcioglu, O

2009-04-01

High magnetic fields used in magnetic resonance imaging (MRI) do not allow the employment of conventional motors due to various incompatibility issues. This paper reports on a new motor that can operate in or near high field magnets used for MRI. The motor was designed to be operational with the MRI equipment and could be used in a rotating imaging gantry inside the magnet designed for dual modality imaging. Furthermore, it could also be used for image guided robotic interventional procedures inside a MRI system if so desired. The prototype motor was developed using magnetic resonance (MR) compatible materials, and its functionality with MR imaging was evaluated experimentally by measuring the performance of the motor and its effect on the MR image quality. Since in our application, namely, single photon emission tomography, the motor has to perform precise stepping of the gantry in small angular steps the most important parameter is the start-up torque. The experimental results showed that the motor has a start-up torque up to 1.37 Nm and rotates at 196 rpm when a constant voltage difference of 12 V is applied at a magnetic field strength of 1 T. The MR image quality was quantified by measuring the signal-to-noise of images acquired under different conditions. The results presented here indicate that the motor is MR compatible and could be used for rotating an imaging gantry or a surgical device inside the magnet.

X-ray magnetic circular dichroism used to image magnetic domains

CERN Document Server

Fischer, P; Kalchgruber, R; Schütz, G M; Schmahl, G; Guttmann, P; Bayreuther, G

1999-01-01

A new technique to image magnetic domain structures has been established by the combination of the high resolution transmission X- ray microscope (TXM) at BESSY I based on the zone plate technique with the X-ray magnetic circular $9 dichroism (X-MCD) providing a huge magnetic contrast. A lateral spatial resolution down to 30 nm could be achieved. Basic features of X-MCD are the inherent element- specificity and the potential to gain information on the local spin $9 and orbital moments of the absorbing species applying magneto-optical sum rules. Key results at the Fe L/sub 3,2/ edges of Fe in a layered GdFe system and at the Co L/sub 3/ edge of a PtCo layered system demonstrate the potential of $9 this microscopy. The images can be recorded in varying magnetic fields which allows to study the evolution of magnetic domains within a complete hysteresis loop. (8 refs).

Magnetic resonance imaging in the evaluation of periosteal reactions

Energy Technology Data Exchange (ETDEWEB)

Nogueira-Barbosa, Marcello Henrique; Trad, Clovis Simao; Muglia, Valdair Francisco; Elias Junior, Jorge; Simao, Marcelo Novelino, E-mail: marcello@fmrp.usp.b [Universidade de Sao Paulo (USP), Ribeirao Preto, SP (Brazil). Faculdade de Medicina. Centro de Ciencias das Imagens e Fisica Medica; Sa, Jose Luiz de [Universidade de Sao Paulo (USP), Ribeirao Preto, SP (Brazil). Faculdade de Medicina. Hospital das Clinicas; Oliveira, Rodrigo Cecilio Vieira de [Clinica de Diagnostico por Imagem Tomoson, Aracatuba, SP (Brazil); Engel, Edgard Eduard [Universidade de Sao Paulo (USP), Ribeirao Preto, SP (Brazil). Faculdade de Medicina. Dept. de Biomecanica, Medicina e Reabilitacao do Aparelho Locomotor

2010-07-15

The objective of the present essay was to encourage a careful evaluation of periosteal reactions on magnetic resonance images. The initial approach to bone lesions is made by conventional radiography and, based on the imaging findings, periosteal reactions are classified into classical subtypes. Although magnetic resonance imaging is considered as the gold standard for local staging of bone tumors, the utilization of such method in the study of periosteal reactions related to focal bone lesions has been poorly emphasized, with relatively few studies approaching this subject. The literature review revealed a study describing an experimental animal model of osteomyelitis suggesting that magnetic resonance imaging is superior to other imaging methods in the early identification of periosteal reactions. Another study has suggested a good correlation between conventional radiography and magnetic resonance imaging in the identification and classification of periosteal reactions in cases of osteosarcoma. The present essay illustrates cases of periosteal reactions observed at magnetic resonance imaging in correlation with findings of conventional radiography or other imaging methods. (author)

Magnetic resonance imaging in the evaluation of periosteal reactions

International Nuclear Information System (INIS)

Nogueira-Barbosa, Marcello Henrique; Trad, Clovis Simao; Muglia, Valdair Francisco; Elias Junior, Jorge; Simao, Marcelo Novelino; Engel, Edgard Eduard

2010-01-01

The objective of the present essay was to encourage a careful evaluation of periosteal reactions on magnetic resonance images. The initial approach to bone lesions is made by conventional radiography and, based on the imaging findings, periosteal reactions are classified into classical subtypes. Although magnetic resonance imaging is considered as the gold standard for local staging of bone tumors, the utilization of such method in the study of periosteal reactions related to focal bone lesions has been poorly emphasized, with relatively few studies approaching this subject. The literature review revealed a study describing an experimental animal model of osteomyelitis suggesting that magnetic resonance imaging is superior to other imaging methods in the early identification of periosteal reactions. Another study has suggested a good correlation between conventional radiography and magnetic resonance imaging in the identification and classification of periosteal reactions in cases of osteosarcoma. The present essay illustrates cases of periosteal reactions observed at magnetic resonance imaging in correlation with findings of conventional radiography or other imaging methods. (author)

Three-dimensional power Doppler sonography in screening for carotid artery disease.

Science.gov (United States)

Keberle, M; Jenett, M; Beissert, M; Jahns, R; Haerten, R; Hahn, D

2000-01-01

Color Doppler sonography has gained considerable recognition as a noninvasive method to detect carotid artery disease and to assess the degree of carotid artery stenosis. However, results are highly operator-dependent and cannot be presented as survey images. The purpose of this study was to evaluate real-time 3-dimensional (3D) power Doppler sonography as a method for screening for atherosclerosis in the carotid arteries. We prospectively screened 75 patients for carotid artery disease using both conventional color Doppler sonography and 3D power Doppler sonography, and the results from the 2 modalities were compared. A total of 150 common carotid arteries, 150 internal carotid arteries, and 150 external carotid arteries were examined utilizing a 7.5-MHz linear-array transducer combined with tissue harmonic imaging. Color Doppler sonography detected 297 normal or atherosclerotic arteries without stenosis, 57 arteries with mild (1-49%) stenosis, 41 with moderate (50-69%) stenosis, 32 with severe (70-99%) stenosis, and 9 with occlusions. The degree of stenosis determined by color Doppler sonography correlated with that determined by 3D power Doppler sonography (r = 0.982-0.998). Moreover, there was a good correlation between the measurements for both the length of the lesion and its distance from the bulb as determined by the 3D volume surveys and by color Doppler sonography (r = 0.986). The interobserver variability rate was 3.7% +/- 0.5%. Generally, the acquisition and reconstruction of the 3D data took less than 5 minutes. 3D power Doppler sonography is easy to perform and is an accurate method in screening for atherosclerotic lesions of the carotid arteries. Moreover, it provides excellent 3D volume surveys that may be helpful in the planning of surgical treatment. Copyright 2000 John Wiley & Sons, Inc.

An NV-Diamond Magnetic Imager for Neuroscience

Science.gov (United States)

Turner, Matthew; Schloss, Jennifer; Bauch, Erik; Hart, Connor; Walsworth, Ronald

2017-04-01

We present recent progress towards imaging time-varying magnetic fields from neurons using nitrogen-vacancy centers in diamond. The diamond neuron imager is noninvasive, label-free, and achieves single-cell resolution and state-of-the-art broadband sensitivity. By imaging magnetic fields from injected currents in mammalian neurons, we will map functional neuronal network connections and illuminate biophysical properties of neurons invisible to traditional electrophysiology. Furthermore, through enhancing magnetometer sensitivity, we aim to demonstrate real-time imaging of action potentials from networks of mammalian neurons.

Children's (Pediatric) Magnetic Resonance Imaging

Medline Plus

Full Text Available ... of which shows a thin slice of the body. The images can then be studied from different angles by ... about radiology? Share your patient story here Images ... Articles and Media Catheter Angiography Magnetic Resonance, Functional (fMRI) - Brain Children's ( ...

Magnetic Resonance Imaging (MRI) -- Head

Medline Plus

Full Text Available Toggle navigation Test/Treatment Patient Type Screening/Wellness Disease/Condition Safety En Español More Info Images/Videos About Us News Physician ... Magnetic resonance imaging (MRI) is a noninvasive medical test that physicians use to diagnose medical conditions. MRI ...

Children's (Pediatric) Magnetic Resonance Imaging

Medline Plus

Full Text Available Toggle navigation Test/Treatment Patient Type Screening/Wellness Disease/Condition Safety En Español More Info Images/Videos About Us News Physician ... Magnetic resonance imaging (MRI) is a noninvasive medical test that physicians use to diagnose medical conditions. MRI ...

New concepts in cardiac imaging 1985

Energy Technology Data Exchange (ETDEWEB)

Pohost, G.M.; Higgins, C.B.; Morganroth, J.; Ritchie, J.L.; Schelbert, H.R.

1985-01-01

This book presents 5 specialists work on reviewing and editing the area of applications for cardiac imaging: Contents: Ultrasound Methods; 1. Echocardiography in Valvular Heart Disease, 2. Echocardiography in Ischemic Heart Disease, 3. Current Status of Doppler Ultrasound for Assessing Regurgitant Valvular Lesions, Radionuclide Methods; 4. Cardiovascular Nuclear Medicine, 5. Single Photon Emission Computed Tomography (SPECT): Validation and Application for Myocardial Perfusion Imaging, 6. Assessment of Regional Myocardial Perfusion with Positron Emission Tomography, 7. Assessment of Regional Myocardial Substrate Metabolism with Positron Emission Tomography, X-Ray Imaging Techniques; 8. The Evaluation of Left Ventricular Function in Ischemic Heart Disease by Digital Subtraction Angigraphy, 9. Digital Angiography in the Assessment of Coronary Artery Disease, 10. Cardiac Computed Tomography: Its Potential Use in Evaluation of Ischemic Heart Disease, Magnetic Methods; 11. NMR Evaluation of the Cardiovascular System, 12. Magnetic Resonance Imaging of the Heart.

New concepts in cardiac imaging 1985

International Nuclear Information System (INIS)

Pohost, G.M.; Higgins, C.B.; Morganroth, J.; Ritchie, J.L.; Schelbert, H.R.

1985-01-01

This book presents 5 specialists work on reviewing and editing the area of applications for cardiac imaging: Contents: Ultrasound Methods; 1. Echocardiography in Valvular Heart Disease, 2. Echocardiography in Ischemic Heart Disease, 3. Current Status of Doppler Ultrasound for Assessing Regurgitant Valvular Lesions, Radionuclide Methods; 4. Cardiovascular Nuclear Medicine, 5. Single Photon Emission Computed Tomography (SPECT): Validation and Application for Myocardial Perfusion Imaging, 6. Assessment of Regional Myocardial Perfusion with Positron Emission Tomography, 7. Assessment of Regional Myocardial Substrate Metabolism with Positron Emission Tomography, X-Ray Imaging Techniques; 8. The Evaluation of Left Ventricular Function in Ischemic Heart Disease by Digital Subtraction Angigraphy, 9. Digital Angiography in the Assessment of Coronary Artery Disease, 10. Cardiac Computed Tomography: Its Potential Use in Evaluation of Ischemic Heart Disease, Magnetic Methods; 11. NMR Evaluation of the Cardiovascular System, 12. Magnetic Resonance Imaging of the Heart

Spectral pulsed-wave tissue Doppler imaging lateral-to-septal delay fails to predict clinical or echocardiographic outcome after cardiac resynchronization therapy

NARCIS (Netherlands)

O.I.I. Soliman (Osama Ibrahim Ibrahim); D.A.M.J. Theuns (Dominic); M.L. Geleijnse (Marcel); A. Nemes (Attila); K. Caliskan (Kadir); W.B. Vletter (Wim); L.J.L.M. Jordaens (Luc); F.J. ten Cate (Folkert)

2007-01-01

textabstractAims: The current study sought to assess if pre-implantation lateral-to-septal delay (LSD) ≥60 ms assessed by spectral pulsed-wave myocardial tissue Doppler imaging (PW-TDI) could predict successful long-term outcome after cardiac resynchronization therapy (CRT). Methods and results

Prenatal color Doppler ultrasonographic diagnosis of fetal tetralogy of Fallot

International Nuclear Information System (INIS)

Tan Buqiao

2009-01-01

Objective: To investigate the sonographic findings of tetralogy of Fallot in fetuses. Methods: The data of color Doppler ultrasonography and follow-up results of 5 fetal tetralogy of Fallot were analyzed retrospectively, and their abnormal ultrasound imaging characteristic were summarized. Results: Two cases were proved tetralogy of Fallot by autopsy, and three cases were confirmed to be tetralogy of Fallot by echocardiography after birth. The image features were the main aorta situated above the ventricular septal defect, pulmonary stenosis, no obvious thickening of the right wall. Conclusion: Fetal tetralogy of Fallot have characteristic ultrasound images, prenatal color Doppler ultrasonographic can diagnoses fetal tetralogy of Fallot correctly and has important clinical value. (authors)

Magnetic resonance imaging in the cranio-cervical region

International Nuclear Information System (INIS)

Koschorek, F.; Jensen, H.P.; Terwey, B.

1987-01-01

Since the introduction of nuclear magnetic resonance imaging (NMR) in the neurosurgical and neurological diagnostic this new imaging modality has shown to be of high diagnostic value - especially in disease process of the cranio-vertebral junction. Other imaging moralities such as x-ray CT and myelography are of inferior quality as the images are degraded by bone artifacts and superposition of other structures. NMR can reveal many aspects of the cranio-vertebral region in a single examination without artifacts from surrounding structures. A further improvement of NMR is the introduction of para-magnetic agents, such as gadolinium-DTPA, as it increases the specifity by dynamic magnetic resonance imaging. The authors present a review of their clinical experience

Normal perinatal and paediatric postmortem magnetic resonance imaging appearances

Energy Technology Data Exchange (ETDEWEB)

Arthurs, Owen J. [Department of Radiology, Great Ormond Street Hospital for Children NHS Foundation Trust, London (United Kingdom); UCL Institute of Child Health, London (United Kingdom); Barber, Joy L. [Department of Radiology, Great Ormond Street Hospital for Children NHS Foundation Trust, London (United Kingdom); Taylor, Andrew M. [Cardiorespiratory Division, Great Ormond Street Hospital for Children NHS Foundation Trust, London (United Kingdom); UCL Institute of Cardiovascular Science, Centre for Cardiovascular Imaging, London (United Kingdom); Sebire, Neil J. [UCL Institute of Child Health, London (United Kingdom); Department of Histopathology, Great Ormond Street Hospital for Children NHS Foundation Trust, London (United Kingdom)

2015-04-01

As postmortem imaging becomes more widely used following perinatal and paediatric deaths, the correct interpretation of images becomes imperative, particularly given the increased use of postmortem magnetic resonance imaging. Many pathological processes may have similar appearances in life and following death. A thorough knowledge of normal postmortem changes is therefore required within postmortem magnetic resonance imaging to ensure that these are not mistakenly interpreted as significant pathology. Similarly, some changes that are interpreted as pathological if they occur during life may be artefacts on postmortem magnetic resonance imaging that are of limited significance. This review serves to illustrate briefly those postmortem magnetic resonance imaging changes as part of the normal changes after death in fetuses and children, and highlight imaging findings that may confuse or mislead an observer to identifying pathology where none is present. (orig.)

Myocardial response to a triathlon in male athletes evaluated by Doppler tissue imaging and biochemical parameters

DEFF Research Database (Denmark)

Leetmaa, T H; Dam, A; Glintborg, D

2008-01-01

(cTnT) and pro-brain natriuretic peptide (pro-BNP)] and echocardiography. Conventional echocardiography techniques and new Doppler tissue imaging (DTI) modalities were applied before and immediately after the competition. Blood samples were drawn 1 week before, immediately after and 12-24 h post...... and systolic velocities decreased, thus suggesting reversible cardiac fatigue. When using cardiac markers and echocardiographic findings, a triathlon was found to have no significant negative effects on left ventricular function or myocardial tissue in male athletes....

Christian Andreas Doppler--the man and his legacy.

Science.gov (United States)

Coman, I M

2005-01-01

Reminding the life and legacy of the Austrian Scientist who discovered the famous 'Doppler Effect'. C.A. Doppler was born the 29th of November 1803 in Salzburg. After studies in Linz and Vienna, he graduated in mathematics, became assistant at the University and later worked as a professor in Prague. Back to Vienna, he was appointed as professor at the Polytechnic School and --in 1850--as first director of the new Institute of Physics. C.A. Doppler did publish on magnetism, electricity, optics, and astronomy. He remains in the history of science due to the discovery presented (May 25, 1842) at the Royal Bohemian Society of Science entitled "On the colored light of the double stars and certain other stars of the heavens"; the paper described (applied to light) the shift of frequency which bears nowadays his name. The theory was later experimentally proven and--extended for any electromagnetic and acoustic waves--got myriads if applications in astronomy, physics, aviation, meteorology, and health science. Satomura in Japan (1955) published it's first ultrasound vascular application--with successive achievements in the next decades. Doppler ultrasonagraphy became the main noninvasive instrument for functional assesment of heart and vessels.

Cost-effectiveness of laser Doppler imaging in burn care in the Netherlands

Directory of Open Access Journals (Sweden)

Hop M Jenda

2013-02-01

Full Text Available Abstract Background Early accurate assessment of burn depth is important to determine the optimal treatment of burns. The method most used to determine burn depth is clinical assessment, which is the least expensive, but not the most accurate. Laser Doppler imaging (LDI is a technique with which a more accurate (>95% estimate of burn depth can be made by measuring the dermal perfusion. The actual effect on therapeutic decisions, clinical outcomes and the costs of the introduction of this device, however, are unknown. Before we decide to implement LDI in Dutch burn care, a study on the effectiveness and cost-effectiveness of LDI is necessary. Methods/design A multicenter randomised controlled trial will be conducted in the Dutch burn centres: Beverwijk, Groningen and Rotterdam. All patients treated as outpatient or admitted to a burn centre within 5 days post burn, with burns of indeterminate depth (burns not obviously superficial or full thickness and a total body surface area burned of ≤ 20% are eligible. A total of 200 patients will be included. Burn depth will be diagnosed by both clinical assessment and laser Doppler imaging between 2–5 days post burn in all patients. Subsequently, patients are randomly divided in two groups: ‘new diagnostic strategy’ versus ‘current diagnostic strategy’. The results of the LDI-scan will only be provided to the treating clinician in the ‘new diagnostic strategy’ group. The main endpoint is the effect of LDI on wound healing time. In addition we measure: a the effect of LDI on other patient outcomes (quality of life, scar quality, b the effect of LDI on diagnostic and therapeutic decisions, and c the effect of LDI on total (medical and non-medical costs and cost-effectiveness. Discussion This trial will contribute to our current knowledge on the use of LDI in burn care and will provide evidence on its cost-effectiveness. Trial registration NCT01489540

Iron oxide nanoparticle-micelles (ION-micelles for sensitive (molecular magnetic particle imaging and magnetic resonance imaging.

Directory of Open Access Journals (Sweden)

Lucas W E Starmans

Full Text Available BACKGROUND: Iron oxide nanoparticles (IONs are a promising nanoplatform for contrast-enhanced MRI. Recently, magnetic particle imaging (MPI was introduced as a new imaging modality, which is able to directly visualize magnetic particles and could serve as a more sensitive and quantitative alternative to MRI. However, MPI requires magnetic particles with specific magnetic properties for optimal use. Current commercially available iron oxide formulations perform suboptimal in MPI, which is triggering research into optimized synthesis strategies. Most synthesis procedures aim at size control of iron oxide nanoparticles rather than control over the magnetic properties. In this study, we report on the synthesis, characterization and application of a novel ION platform for sensitive MPI and MRI. METHODS AND RESULTS: IONs were synthesized using a thermal-decomposition method and subsequently phase-transferred by encapsulation into lipidic micelles (ION-Micelles. Next, the material and magnetic properties of the ION-Micelles were analyzed. Most notably, vibrating sample magnetometry measurements showed that the effective magnetic core size of the IONs is 16 nm. In addition, magnetic particle spectrometry (MPS measurements were performed. MPS is essentially zero-dimensional MPI and therefore allows to probe the potential of iron oxide formulations for MPI. ION-Micelles induced up to 200 times higher signal in MPS measurements than commercially available iron oxide formulations (Endorem, Resovist and Sinerem and thus likely allow for significantly more sensitive MPI. In addition, the potential of the ION-Micelle platform for molecular MPI and MRI was showcased by MPS and MRI measurements of fibrin-binding peptide functionalized ION-Micelles (FibPep-ION-Micelles bound to blood clots. CONCLUSIONS: The presented data underlines the potential of the ION-Micelle nanoplatform for sensitive (molecular MPI and warrants further investigation of the Fib

Power Doppler Ultrasonography and Shear Wave Elastography as Complementary Imaging Methods for Suspected Local Breast Cancer Recurrence.

Science.gov (United States)

Jales, Rodrigo Menezes; Dória, Maira Teixeira; Serra, Kátia Piton; Miranda, Mila Meneguelli; Menossi, Carlos Alberto; Schumacher, Klaus; Sarian, Luis Otávio

2018-06-01

To prospectively investigate the diagnostic accuracy and clinical consequences of power Doppler morphologic criteria and shear wave elastography (SWE) as complementary imaging methods for evaluation of suspected local breast cancer recurrence in the ipsilateral breast or chest wall. Thirty-two breast masses with a suspicion of local breast cancer recurrence on B-mode ultrasonography underwent complementary power Doppler and SWE evaluations. Power Doppler morphologic criteria were classified as avascular, hypovascular, or hypervascular. Shear wave elastography was classified according to a 5-point scale (SWE score) and SWE maximum elasticity. Diagnostic accuracy was assessed by the sensitivity, specificity, and area under the curve. A decision curve analysis assessed clinical consequences of each method. The reference standard for diagnosis was defined as core needle or excisional biopsy. Histopathologic examinations revealed 9 (28.2%) benign and 23 (71.8%) malignant cases. Power Doppler ultrasonography (US) had sensitivity of 34.8% (95% confidence interval [CI], 6.6%-62.9%) and specificity of 45.4% (95% CI, 19.3%-71.5%). The SWE score (≥3) had sensitivity of 87.0% (95% CI, 66.4%-97.2%) and specificity of 44.4% (95% CI, 13.7%-78.8%). The SWE maximum elasticity (velocity > 6.5cm/s) had sensitivity of 87% (95% CI, 66.4%-97.2%) and specificity of 77.8% (95% CI, 40.0% to 97.2%). The areas under the curves for the SWE score and SWE maximum elasticity were 0.71 (95% CI, 0.53-0.87) and 0.82 (95% CI, 0.64-0.93), respectively (P = .32). Power Doppler US is unsuitable for discrimination between local breast cancer recurrence and fibrosis. Although the SWE score and SWE maximum elasticity can make this discrimination, the use of these methods to determine biopsy may lead to poorer clinical outcomes than the current practice of performing biopsies of all suspicious masses. © 2017 by the American Institute of Ultrasound in Medicine.

Alveolar Echinococcosis of the Liver: Correlative Color Doppler US, CT, and MRI Study

International Nuclear Information System (INIS)

Cokun, A.; Oeztuerk, M.; Karahan, O.I.; Erdogan, N.; Ikin, S.; Guelec, M.

2004-01-01

Purpose: To determine and compare the imaging features of hepatic alveolar Echinococcosis using color Doppler US, CT, and MRI. Material and Methods: Abdominal CT and MRI with and without contrast agents and color Doppler US were performed on seven patients with hepatic alveolar Echinococcosis. The lesions were evaluated for location, features of echogenicity, intensity and density, calcification, and vascular, hilar, and perihepatic involvement. The diagnosis was confirmed histopathologically in all patients. Results: Six patients had solitary lesions, and one displayed multiple lesions. The lesions were generally seen as heterogeneous and hyper- or hypoechoic when imaged with color Doppler US, hypodense with CT, and hypointense with MRI, in comparison with the liver parenchyma. Calcification, central necrosis, and small peripheral cysts were observed in six, seven, and four patients, respectively. Vascular flow or contrast enhancement was not observed in any of the cases. A look at the respective advantages of each method reveals that calcification was best rendered visible via CT, small peripheral cysts with T2-weighted MRI, central necrosis with CT and MRI, and perihepatic invasion with multiplanar MRI. Vascular involvement was revealed by all methods. Conclusion: Color Doppler US, CT, and MR imaging function extremely well as complementary methods in the diagnosis of HAE. Color Doppler US should be performed in these patients owing to its ability to efficiently detect the disease. Knowledge of imaging characteristics makes it possible to radiologically ascertain an early diagnosis

Content Based Retrieval System for Magnetic Resonance Images

International Nuclear Information System (INIS)

Trojachanets, Katarina

2010-01-01

The amount of medical images is continuously increasing as a consequence of the constant growth and development of techniques for digital image acquisition. Manual annotation and description of each image is impractical, expensive and time consuming approach. Moreover, it is an imprecise and insufficient way for describing all information stored in medical images. This induces the necessity for developing efficient image storage, annotation and retrieval systems. Content based image retrieval (CBIR) emerges as an efficient approach for digital image retrieval from large databases. It includes two phases. In the first phase, the visual content of the image is analyzed and the feature extraction process is performed. An appropriate descriptor, namely, feature vector is then associated with each image. These descriptors are used in the second phase, i.e. the retrieval process. With the aim to improve the efficiency and precision of the content based image retrieval systems, feature extraction and automatic image annotation techniques are subject of continuous researches and development. Including the classification techniques in the retrieval process enables automatic image annotation in an existing CBIR system. It contributes to more efficient and easier image organization in the system.Applying content based retrieval in the field of magnetic resonance is a big challenge. Magnetic resonance imaging is an image based diagnostic technique which is widely used in medical environment. According to this, the number of magnetic resonance images is enormously growing. Magnetic resonance images provide plentiful medical information, high resolution and specific nature. Thus, the capability of CBIR systems for image retrieval from large database is of great importance for efficient analysis of this kind of images. The aim of this thesis is to propose content based retrieval system architecture for magnetic resonance images. To provide the system efficiency, feature

State of the art magnetic resonance imaging

International Nuclear Information System (INIS)

Weissman, J.D.

1987-01-01

In less than a decade Magnetic Resonance Imaging (MRI) has evolved from a laboratory demonstration to a safe and effective technique for clinical diagnosis. This evolutionary process continues. At this time 2-D and 3-D imaging of the head and body is firmly established in clinical use. Surface coil imaging, two-component chemical shift imaging, in-vivo spectroscopy and flow imaging are currently in various stages of development. The present state of the art of MRI is a function of an array of technologies: magnet, Rf coil, Rf pulse amplifier, gradient coil and driver, pulse programmer, A/D converter, computer system architecture, array processors and mass storage (both magnetic and optical). The overall product design is the result of a complex process which balances the advantages and disadvantages of each component for optimal system performance and flexibility. The author discusses the organization of a state-of-the-art MRI system. Several examples of the kinds of system interactions affecting design choices are given. (Auth.)

Imaging pediatric magnet ingestion with surgical-pathological correlation.

Science.gov (United States)

Otjen, Jeffrey P; Rohrmann, Charles A; Iyer, Ramesh S

2013-07-01

Foreign body ingestion is a common problem in the pediatric population and a frequent cause for emergency room visits. Magnets are common household objects that when ingested can bring about severe, possibly fatal gastrointestinal complications. Radiography is an integral component of the management of these children. Pediatric and emergency radiologists alike must be aware of imaging manifestations of magnet ingestion, as their identification drives decision-making for consulting surgeons and gastroenterologists. Radiology can thus substantially augment the clinical history and physical exam, facilitating appropriate management. This manuscript sequentially presents cases of magnet ingestion featuring imaging findings coupled with surgical and pathological correlation. Each case is presented to highlight ways in which the radiologist can make impactful contributions to diagnosis and management. Clinical overview with pitfalls of magnet ingestion imaging and an imaging decision tree will also be presented.

Imaging pediatric magnet ingestion with surgical-pathological correlation

International Nuclear Information System (INIS)

Otjen, Jeffrey P.; Iyer, Ramesh S.; Rohrmann, Charles A.

2013-01-01

Foreign body ingestion is a common problem in the pediatric population and a frequent cause for emergency room visits. Magnets are common household objects that when ingested can bring about severe, possibly fatal gastrointestinal complications. Radiography is an integral component of the management of these children. Pediatric and emergency radiologists alike must be aware of imaging manifestations of magnet ingestion, as their identification drives decision-making for consulting surgeons and gastroenterologists. Radiology can thus substantially augment the clinical history and physical exam, facilitating appropriate management. This manuscript sequentially presents cases of magnet ingestion featuring imaging findings coupled with surgical and pathological correlation. Each case is presented to highlight ways in which the radiologist can make impactful contributions to diagnosis and management. Clinical overview with pitfalls of magnet ingestion imaging and an imaging decision tree will also be presented. (orig.)

Magnetic resonance imaging of breast implants.

Science.gov (United States)

Shah, Mala; Tanna, Neil; Margolies, Laurie

2014-12-01

Silicone breast implants have significantly evolved since their introduction half a century ago, yet implant rupture remains a common and expected complication, especially in patients with earlier-generation implants. Magnetic resonance imaging is the primary modality for assessing the integrity of silicone implants and has excellent sensitivity and specificity, and the Food and Drug Administration currently recommends periodic magnetic resonance imaging screening for silent silicone breast implant rupture. Familiarity with the types of silicone implants and potential complications is essential for the radiologist. Signs of intracapsular rupture include the noose, droplet, subcapsular line, and linguine signs. Signs of extracapsular rupture include herniation of silicone with a capsular defect and extruded silicone material. Specific sequences including water and silicone suppression are essential for distinguishing rupture from other pathologies and artifacts. Magnetic resonance imaging provides valuable information about the integrity of silicone implants and associated complications.

Magnetic resonance imaging of radiation optic neuropathy

International Nuclear Information System (INIS)

Zimmerman, C.F.; Schatz, N.J.; Glaser, J.S.

1990-01-01

Three patients with delayed radiation optic neuropathy after radiation therapy for parasellar neoplasms underwent magnetic resonance imaging. The affected optic nerves and chiasms showed enlargement and focal gadopentetate dimeglumine enhancement. The magnetic resonance imaging technique effectively detected and defined anterior visual pathway changes of radionecrosis and excluded the clinical possibility of visual loss because of tumor recurrence

Fetal cardiac stroke volume determination by four-dimensional ultrasound with spatio-temporal image correlation compared with two-dimensional and Doppler ultrasonography.

Science.gov (United States)

Rizzo, Giuseppe; Capponi, Alessandra; Cavicchioni, Ottavia; Vendola, Marianne; Arduini, Domenico

2007-12-01

To assess the agreement of stroke volume (SV) measured with two-dimensional (2D) ultrasonography with Doppler capability (vs) four-dimensional (4D) with spatiotemporal image correlation (STIC) in normal and growth restricted fetuses. 2D Doppler and 4D STIC were used to measure SV of 40 normal fetuses at 20 to 22 and 28 to 32 weeks, and 16 growth-restricted fetuses at 26 to 34 weeks of gestation. Intraclass correlation was used to evaluate the agreement between left and right SV obtained by the two techniques, and proportionate Bland-Altman plots constructed. The time necessary to obtain SV was analyzed. The intraclass correlation coefficient between 2D Doppler and 4D STIC measurements for the left ventricle were 0.977 and 0.980 for the right ventricle. The proportionate limits of agreement between the two methods were 18.7 to 23.9% for the left ventricle and - 20.9 to 21.7% for the right ventricle. The time necessary to measure SV was significantly shorter with 4D STIC (3.1 (vs) 7.9 min p < 0.0001) than with 2D Doppler. There is a good agreement between SV measured either by 2D Doppler or by 4D STIC. The 4D STIC represents a simple and rapid technique to estimate fetal SV and promises to become the method of choice. Copyright (c) 2007 John Wiley & Sons, Ltd.

Attenuated Vector Tomography -- An Approach to Image Flow Vector Fields with Doppler Ultrasonic Imaging

International Nuclear Information System (INIS)

Huang, Qiu; Peng, Qiyu; Huang, Bin; Cheryauka, Arvi; Gullberg, Grant T.

2008-01-01

The measurement of flow obtained using continuous wave Doppler ultrasound is formulated as a directional projection of a flow vector field. When a continuous ultrasound wave bounces against a flowing particle, a signal is backscattered. This signal obtains a Doppler frequency shift proportional to the speed of the particle along the ultrasound beam. This occurs for each particle along the beam, giving rise to a Doppler velocity spectrum. The first moment of the spectrum provides the directional projection of the flow along the ultrasound beam. Signals reflected from points further away from the detector will have lower amplitude than signals reflected from points closer to the detector. The effect is very much akin to that modeled by the attenuated Radon transform in emission computed tomography.A least-squares method was adopted to reconstruct a 2D vector field from directional projection measurements. Attenuated projections of only the longitudinal projections of the vector field were simulated. The components of the vector field were reconstructed using the gradient algorithm to minimize a least-squares criterion. This result was compared with the reconstruction of longitudinal projections of the vector field without attenuation. If attenuation is known, the algorithm was able to accurately reconstruct both components of the full vector field from only one set of directional projection measurements. A better reconstruction was obtained with attenuation than without attenuation implying that attenuation provides important information for the reconstruction of flow vector fields.This confirms previous work where we showed that knowledge of the attenuation distribution helps in the reconstruction of MRI diffusion tensor fields from fewer than the required measurements. In the application of ultrasound the attenuation distribution is obtained with pulse wave transmission computed tomography and flow information is obtained with continuous wave Doppler

Nuclear magnetic resonance imaging

International Nuclear Information System (INIS)

Young, I.R.

1984-01-01

In a method of imaging a body in which nuclear magnetic resonance is excited in a region including part of the body, and the free induction decay signal is measured, a known quantity of a material of known nuclear magnetic resonance properties, for example a bag of water, is included in the region so as to enhance the measured free induction decay signal. This then reduces the generation of noise during subsequent processing of the signal. (author)

Dental magnetic resonance imaging

International Nuclear Information System (INIS)

Hilgenfeld, Tim; Bendszus, Martin; Haehnel, Stefan

2016-01-01

Growing distribution and utilization of digital volume tomography (DVT) extend the spectrum of clinical dental imaging. Additional diagnostic value, however, comes along with an increasing amount of radiation. In contrast, magnetic resonance imaging is a radiation free imaging technique. Furthermore, it offers a high soft tissue contrast. Morphological and numerical dental anomalies, differentiation of periapical lesions and exclusion of complications of dental diseases are field of applications for dental MRI. In addition, detection of caries and periodontal lesions and injury of inferior alveolar nerve are promising application areas in the future.

Cranial magnetic resonance imaging

International Nuclear Information System (INIS)

Elster, A.D.

1988-01-01

Cranial Magnetic Resonance Imaging is comprehensive, well structured, and well written. The material is current and well referenced. The illustrations are good and complement the text well. The overall quality of publication is above average. The greatest attribute of the book is its readability. The author demonstrates ample skill in making complex subjects, such as MR physics and imaging of cerebral hemorrhage, easy to understand. The book closes with a detailed atlas on the anatomic appearance of the brain on MR images in the axial, coronal, and sagittal planes

Tissue Doppler imaging of carotid plaque wall motion: a pilot study

Directory of Open Access Journals (Sweden)

Naylor A Ross

2003-12-01

Full Text Available Abstract Background Studies suggest the physical and mechanical properties of vessel walls and plaque may be of clinical value in the diagnosis and treatment of cardiovascular atherosclerotic disease. The purpose of this pilot study was to investigate the potential clinical application of ultrasound Tissue Doppler Imaging (TDI of Arterial Wall Motion (AWM and to quantify simple wall motion indices in normal and diseased carotid arteries. Methods 224 normal and diseased carotid arteries (0–100% stenoses were imaged in 126 patients (age 25–88 years, mean 68 ± 11. Longitudinal sections of the carotid bifurcation were imaged using a Philips HDI5000 scanner and L12-5 probe under optimized TDI settings. Temporal and spatial AWMs were analyzed to evaluate the vessel wall displacements and spatial gradients at peak systole averaged over 5 cardiac cycles. Results AWM data were successfully extracted in 91% of cases. Within the carotid bifurcation/plaque region, the maximum wall dilation at peak systole ranged from -100 to 750 microns, mean 335 ± 138 microns. Maximum wall dilation spatial gradients ranged 0–0.49, mean 0.14 ± 0.08. The AWM parameters showed a wide variation and had poor correlation with stenoses severity. Case studies illustrated a variety of pertinent qualitative and quantitative wall motion features related to the biophysics of arterial disease. Conclusion Our clinical experience, using a challenging but realistic imaging protocol, suggests the use of simple quantitative AWM measures may have limitations due to high variability. Despite this, pertinent features of AWM in normal and diseased arteries demonstrate the potential clinical benefit of the biomechanical information provided by TDI.

Magnonic holographic imaging of magnetic microstructures

Science.gov (United States)

Gutierrez, D.; Chiang, H.; Bhowmick, T.; Volodchenkov, A. D.; Ranjbar, M.; Liu, G.; Jiang, C.; Warren, C.; Khivintsev, Y.; Filimonov, Y.; Garay, J.; Lake, R.; Balandin, A. A.; Khitun, A.

2017-04-01

We propose and demonstrate a technique for magnetic microstructure imaging via their interaction with propagating spin waves. In this approach, the object of interest is placed on top of a magnetic testbed made of material with low spin wave damping. There are micro-antennas incorporated in the testbed. Two of these antennas are used for spin wave excitation while another one is used for the detecting of inductive voltage produced by the interfering spin waves. The measurements are repeated for different phase differences between the spin wave generating antennas which is equivalent to changing the angle of illumination. The collected data appear as a 3D plot - the holographic image of the object. We present experimental data showing magnonic holographic images of a low-coercivity Si/Co sample, a high-coercivity sample made of SrFe12O19 and a diamagnetic copper sample. We also present images of the three samples consisting of a different amount of SrFe12O19 powder. The imaging was accomplished on a Y3Fe2(FeO4)3 testbed at room temperature. The obtained data reveal the unique magnonic signatures of the objects. Experimental data is complemented by the results of numerical modeling, which qualitatively explain the characteristic features of the images. Potentially, magnonic holographic imaging may complement existing techniques and be utilized for non-destructive in-situ magnetic object characterization. The fundamental physical limits of this approach are also discussed.

Multi-site laser Doppler flowmetry for assessing collateral flow in experimental ischemic stroke: Validation of outcome prediction with acute MRI.

Science.gov (United States)

Cuccione, Elisa; Versace, Alessandro; Cho, Tae-Hee; Carone, Davide; Berner, Lise-Prune; Ong, Elodie; Rousseau, David; Cai, Ruiyao; Monza, Laura; Ferrarese, Carlo; Sganzerla, Erik P; Berthezène, Yves; Nighoghossian, Norbert; Wiart, Marlène; Beretta, Simone; Chauveau, Fabien

2017-06-01

High variability in infarct size is common in experimental stroke models and affects statistical power and validity of neuroprotection trials. The aim of this study was to explore cerebral collateral flow as a stratification factor for the prediction of ischemic outcome. Transient intraluminal occlusion of the middle cerebral artery was induced for 90 min in 18 Wistar rats. Cerebral collateral flow was assessed intra-procedurally using multi-site laser Doppler flowmetry monitoring in both the lateral middle cerebral artery territory and the borderzone territory between middle cerebral artery and anterior cerebral artery. Multi-modal magnetic resonance imaging was used to assess acute ischemic lesion (diffusion-weighted imaging, DWI), acute perfusion deficit (time-to-peak, TTP), and final ischemic lesion at 24 h. Infarct volumes and typology at 24 h (large hemispheric versus basal ganglia infarcts) were predicted by both intra-ischemic collateral perfusion and acute DWI lesion volume. Collateral flow assessed by multi-site laser Doppler flowmetry correlated with the corresponding acute perfusion deficit using TTP maps. Multi-site laser Doppler flowmetry monitoring was able to predict ischemic outcome and perfusion deficit in good agreement with acute MRI. Our results support the additional value of cerebral collateral flow monitoring for outcome prediction in experimental ischemic stroke, especially when acute MRI facilities are not available.

Finite magnetic relaxation in x-space magnetic particle imaging: Comparison of measurements and ferrohydrodynamic models.

Science.gov (United States)

Dhavalikar, R; Hensley, D; Maldonado-Camargo, L; Croft, L R; Ceron, S; Goodwill, P W; Conolly, S M; Rinaldi, C

2016-08-03

Magnetic Particle Imaging (MPI) is an emerging tomographic imaging technology that detects magnetic nanoparticle tracers by exploiting their non-linear magnetization properties. In order to predict the behavior of nanoparticles in an imager, it is possible to use a non-imaging MPI relaxometer or spectrometer to characterize the behavior of nanoparticles in a controlled setting. In this paper we explore the use of ferrohydrodynamic magnetization equations for predicting the response of particles in an MPI relaxometer. These include a magnetization equation developed by Shliomis (Sh) which has a constant relaxation time and a magnetization equation which uses a field-dependent relaxation time developed by Martsenyuk, Raikher and Shliomis (MRSh). We compare the predictions from these models with measurements and with the predictions based on the Langevin function that assumes instantaneous magnetization response of the nanoparticles. The results show good qualitative and quantitative agreement between the ferrohydrodynamic models and the measurements without the use of fitting parameters and provide further evidence of the potential of ferrohydrodynamic modeling in MPI.

Second International Workshop on Magnetic Particle Imaging

CERN Document Server

Borgert, Jörn; Magnetic Particle Imaging : A Novel SPIO Nanoparticle Imaging Technique

2012-01-01

Magnetic Particle Imaging (MPI) is a novel imaging modality. In MPI superparamagnetic iron oxide nanoparticles are used as tracer materials. The volume is the proceeding of the 2nd international workshop on magnetic particle imaging (IWMPI). The workshop aims at covering the status and recent developments of both, the instrumentation and the tracer material, as each of them is equally important in designing a well performing MPI. For instance, the current state of the art in magnetic coil design for MPI is discussed. With a new symmetrical arrangement of coils, a field-free line (FFL) can be produced that promises a significantly higher sensitivity compared with the standard arrangement for a FFP. Furthermore, the workshop aims at presenting results from phantom and pre-clinical studies.

Doppler ultrasound for diagnosis of soft tissue sarcoma: efficacy of ultrasound-based screening score

Directory of Open Access Journals (Sweden)

Nagano Satoshi

2015-06-01

Full Text Available Background. The utility of ultrasound imaging in the screening of soft-part tumours (SPTs has been reported. We classified SPTs according to their blood flow pattern on Doppler ultrasound and re-evaluated the efficacy of this imaging modality as a screening method. Additionally, we combined Doppler ultrasound with several values to improve the diagnostic efficacy and to establish a new diagnostic tool.

Capsular contracture and possible implant rupture: is magnetic resonance imaging useful?

Science.gov (United States)

Paetau, Alyssa A; McLaughlin, Sarah A; McNeil, Rebecca B; Sternberg, Erez; TerKonda, Sarvam P; Waldorf, James C; Perdikis, Galen

2010-03-01

Currently, magnetic resonance imaging is considered the accepted standard to evaluate breast implant integrity. To evaluate its utility in diagnosing ruptured silicone implants in the setting of capsular contracture and to correlate the preoperative assessment of implant integrity with or without magnetic resonance imaging with operative findings, 319 capsulectomies (171 patients with capsular contractures) were retrospectively reviewed. Preoperative magnetic resonance imaging was done on 160 implants, whereas the remaining 159 were evaluated using only physical examination and/or mammography. Postoperative results were analyzed to determine the sensitivity, specificity, and accuracy of preoperative magnetic resonance imaging in comparison with clinical and/or mammography evaluation alone. Although occasionally valuable, overall, preoperative magnetic resonance imaging was no more accurate than clinical evaluation with or without mammography in predicting implant status: magnetic resonance imaging 124 of 160 (78 percent) and clinical 121 of 159 (76 percent; p = 0.77). In the setting of capsular contracture, physical examination with or without mammogram is as accurate as magnetic resonance imaging in determining implant integrity. Although magnetic resonance imaging is a sensitive diagnostic tool, in symptomatic patients with capsular contracture, it cannot be viewed as infallible.

Parasellar meningiomas: magnetic resonance imaging findings

International Nuclear Information System (INIS)

Santos, Alair Augusto S.M.D. dos; Fontes, Cristina Asvolinsque P.

2001-01-01

We reviewed 22 cases of patients with parasellar meningiomas evaluated with magnetic resonance imaging (MRI) in private clinics of the cities of Niteroi and Rio de Janeiro, Rio de Janeiro State, Brazil. Our aim was to characterize the imaging findings in this type of tumor. MRI scanners with 0.5 and 1.0 Tesla magnets were used for the acquisition of multiplanar T1-weighted (pre-and post-gadolinium administration) and T2-weighted images. The main symptoms observed were headache and visual disturbances. Hyperprolactinaemia was observed in only one patient. The most frequent imaging finding was a parasellar mass which appeared hypointense on T1-weighted and hyperintense on T2-weighted images, and enhanced intensively after gadolinium administration. MRI is useful to demonstrate the lesion and to asses the damage to adjacent structures, particularly when the patient presents visual disturbances due to involvement of the cavernous sinuses. (author)

Low-frequency high-definition power Doppler in visualizing and defining fetal pulmonary venous connections.

Science.gov (United States)

Liu, Lin; He, Yihua; Li, Zhian; Gu, Xiaoyan; Zhang, Ye; Zhang, Lianzhong

2014-07-01

The use of low-frequency high-definition power Doppler in assessing and defining pulmonary venous connections was investigated. Study A included 260 fetuses at gestational ages ranging from 18 to 36 weeks. Pulmonary veins were assessed by performing two-dimensional B-mode imaging, color Doppler flow imaging (CDFI), and low-frequency high-definition power Doppler. A score of 1 was assigned if one pulmonary vein was visualized, 2 if two pulmonary veins were visualized, 3 if three pulmonary veins were visualized, and 4 if four pulmonary veins were visualized. The detection rate between Exam-1 and Exam-2 (intra-observer variability) and between Exam-1 and Exam-3 (inter-observer variability) was compared. In study B, five cases with abnormal pulmonary venous connection were diagnosed and compared to their anatomical examination. In study A, there was a significant difference between CDFI and low-frequency high-definition power Doppler for the four pulmonary veins observed (P low-frequency high-definition power Doppler was higher than that when employing two-dimensional B-mode imaging or CDFI. There was no significant difference between the intra- and inter-observer variabilities using low-frequency high-definition power Doppler display of pulmonary veins (P > 0.05). The coefficient correlation between Exam-1 and Exam-2 was 0.844, and the coefficient correlation between Exam-1 and Exam-3 was 0.821. In study B, one case of total anomalous pulmonary venous return and four cases of partial anomalous pulmonary venous return were diagnosed by low-frequency high-definition power Doppler and confirmed by autopsy. The assessment of pulmonary venous connections by low-frequency high-definition power Doppler is advantageous. Pulmonary venous anatomy can and should be monitored during fetal heart examination.

System and method for magnetic current density imaging at ultra low magnetic fields

Science.gov (United States)

Espy, Michelle A.; George, John Stevens; Kraus, Robert Henry; Magnelind, Per; Matlashov, Andrei Nikolaevich; Tucker, Don; Turovets, Sergei; Volegov, Petr Lvovich

2016-02-09

Preferred systems can include an electrical impedance tomography apparatus electrically connectable to an object; an ultra low field magnetic resonance imaging apparatus including a plurality of field directions and disposable about the object; a controller connected to the ultra low field magnetic resonance imaging apparatus and configured to implement a sequencing of one or more ultra low magnetic fields substantially along one or more of the plurality of field directions; and a display connected to the controller, and wherein the controller is further configured to reconstruct a displayable image of an electrical current density in the object. Preferred methods, apparatuses, and computer program products are also disclosed.

Differences between Doppler velocities of ions and neutral atoms in a solar prominence

Science.gov (United States)

Anan, T.; Ichimoto, K.; Hillier, A.

2017-05-01

Context. In astrophysical systems with partially ionized plasma, the motion of ions is governed by the magnetic field while the neutral particles can only feel the magnetic field's Lorentz force indirectly through collisions with ions. The drift in the velocity between ionized and neutral species plays a key role in modifying important physical processes such as magnetic reconnection, damping of magnetohydrodynamic waves, transport of angular momentum in plasma through the magnetic field, and heating. Aims: This paper aims to investigate the differences between Doppler velocities of calcium ions and neutral hydrogen in a solar prominence to look for velocity differences between the neutral and ionized species. Methods: We simultaneously observed spectra of a prominence over an active region in H I 397 nm, H I 434 nm, Ca II 397 nm, and Ca II 854 nm using a high dispersion spectrograph of the Domeless Solar Telescope at Hida observatory. We compared the Doppler velocities, derived from the shift of the peak of the spectral lines presumably emitted from optically-thin plasma. Results: There are instances when the difference in velocities between neutral atoms and ions is significant, for example 1433 events ( 3% of sets of compared profiles) with a difference in velocity between neutral hydrogen atoms and calcium ions greater than 3σ of the measurement error. However, we also found significant differences between the Doppler velocities of two spectral lines emitted from the same species, and the probability density functions of velocity difference between the same species is not significantly different from those between neutral atoms and ions. Conclusions: We interpreted the difference of Doppler velocities as being a result of the motions of different components in the prominence along the line of sight, rather than the decoupling of neutral atoms from plasma. The movie attached to Fig. 1 is available at http://www.aanda.org

Relaxation in x-space magnetic particle imaging.

Science.gov (United States)

Croft, Laura R; Goodwill, Patrick W; Conolly, Steven M

2012-12-01

Magnetic particle imaging (MPI) is a new imaging modality that noninvasively images the spatial distribution of superparamagnetic iron oxide nanoparticles (SPIOs). MPI has demonstrated high contrast and zero attenuation with depth, and MPI promises superior safety compared to current angiography methods, X-ray, computed tomography, and magnetic resonance imaging angiography. Nanoparticle relaxation can delay the SPIO magnetization, and in this work we investigate the open problem of the role relaxation plays in MPI scanning and its effect on the image. We begin by amending the x-space theory of MPI to include nanoparticle relaxation effects. We then validate the amended theory with experiments from a Berkeley x-space relaxometer and a Berkeley x-space projection MPI scanner. Our theory and experimental data indicate that relaxation reduces SNR and asymmetrically blurs the image in the scanning direction. While relaxation effects can have deleterious effects on the MPI scan, we show theoretically and experimentally that x-space reconstruction remains robust in the presence of relaxation. Furthermore, the role of relaxation in x-space theory provides guidance as we develop methods to minimize relaxation-induced blurring. This will be an important future area of research for the MPI community.

Sub-Doppler spectroscopy

International Nuclear Information System (INIS)

Hansch, T.W.

1983-01-01

This chapter examines Doppler-free saturation spectroscopy, tunable cw sources, and Doppler-free two-photon spectroscopy. Discusses saturation spectroscopy; continuous wave saturation spectroscopy in the ultraviolet; and two-photon spectroscopy of atomic hydrogen 1S-2S. Focuses on Doppler-free laser spectroscopy of gaseous samples. Explains that in saturation spectroscopy, a monochromatic laser beam ''labels'' a group of atoms within a narrow range of axial velocities through excitation or optical pumping, and a Doppler-free spectrum of these selected atoms is observed with a second, counterpropagating beam. Notes that in two-photon spectroscopy it is possible to record Doppler-free spectra without any need for velocity selection by excitation with two counterpropagating laser beams whose first order Doppler shifts cancel

[Vascular complications following kidney transplant: the role of color-Doppler imaging].

Science.gov (United States)

Granata, Antonio; Floccari, Fulvio; Lentini, Paolo; Vittoria, Salvatore; Di Pietro, Fabio; Zamboli, Pasquale; Fiorini, Fulvio; Fatuzzo, Pasquale

2012-01-01

The progressive decline in the incidence of graft rejection has made urological, surgical, parenchymal and vascular complications of kidney transplant more frequent. The latter, although accounting for only 5-10% of all post-transplant complications, are a frequent cause of graft loss. Ultrasonography, both in B-mode and with Doppler ultrasound, is an important diagnostic tool in case of clinical conditions which might impair kidney function. Even though ultrasonography is considered fundamental in the diagnosis of parenchymal and surgical complications of the transplanted kidney, its role is not fully understood in case of vascular complications of the graft. The specificity of Doppler ultrasound is very important in case of stenosis of the transplanted renal artery, pseudoaneurysms, arteriovenous fistulas, and thrombosis with complete or partial artery or vein occlusion. Doppler and color determinations present high diagnostic accuracy, which is higher in case of successive measurements performed during the follow-up of the graft. Modern techniques including contrast-enhanced ultrasound increase the diagnostic power of ultrasonography in case of vascular complications of the transplanted kidney, planted kidney.

Topical questions in magnetic resonance imaging

International Nuclear Information System (INIS)

Andrew, E.R.; Florida Univ., Gainesville, FL; Florida Univ., Gainesville, FL

1989-01-01

This paper examines a number of practical questions concerning magnetic resonance imaging. These include the choice of operating magnetic field strength, the problem of siting and screening, a procedure for securing precise slice selection and the use of paramagnetic contrast agents. (author). 5 refs

[Surface coils for magnetic-resonance images].

Science.gov (United States)

Rodríguez-González, Alfredo Odón; Amador-Baheza, Ricardo; Rojas-Jasso, Rafael; Barrios-Alvarez, Fernando Alejandro

2005-01-01

Since the introduction of magnetic resonance imaging in Mexico, the development of this important medical imaging technology has been almost non-existing in our country. The very first surface coil prototypes for clinical applications in magnetic resonance imaging has been developed at the Center of Research in Medical Imaging and Instrumentation of the Universidad Autónoma Metropolitana Iztapalapa (Metropolitan Autonomous University, Campus Iztapalapa). Two surface coil prototypes were built: a) a circular-shaped coil and b) a square-shaped coil for multiple regions of the body, such as heart, brain, knee, hands, and ankles. These coils were tested on the 1.5T imager of the ABC Hospital-Tacubaya, located in Mexico City. Brain images of healthy volunteers were obtained in different orientations: sagittal, coronal, and axial. Since images showed a good-enough clinical quality for diagnosis, it is fair to say that these coil prototypes can be used in the clinical environment, and with small modifications, they can be made compatible with almost any commercial scanner. This type of development can offer new alternatives for further collaboration between the research centers and the radiology community, in the search of new applications and developments of this imaging technique.

Comparative Analysis of Logistic Regression, Support Vector Machine and Artificial Neural Network for the Differential Diagnosis of Benign and Malignant Solid Breast Tumors by the Use of Three-Dimensional Power Doppler Imaging

International Nuclear Information System (INIS)

Chen, Shou Tung; Hsiao, Yi Hsuan; Kuo, Shou Jen; Tseng, Hsin Shun; Wu, Hwa Koon; Chen, Dar Ren; Huang, Yu Len

2009-01-01

Logistic regression analysis (LRA), Support Vector Machine (SVM) and a neural network (NN) are commonly used statistical models in computeraided diagnostic (CAD) systems for breast ultrasonography (US). The aim of this study was to clarify the diagnostic ability of the use of these statistical models for future applications of CAD systems, such as three-dimensional (3D) power Doppler imaging, vascularity evaluation and the differentiation of a solid mass. A database that contained 3D power Doppler imaging pairs of non-harmonic and tissue harmonic images for 97 benign and 86 malignant solid tumors was utilized. The virtual organ computer-aided analysis-imaging program was used to analyze the stored volumes of the 183 solid breast tumors. LRA, an SVM and NN were employed in comparative analyses for the characterization of benign and malignant solid breast masses from the database. The values of area under receiver operating characteristic (ROC) curve, referred to as Az values for the use of non-harmonic 3D power Doppler US with LRA, SVM and NN were 0.9341, 0.9185 and 0.9086, respectively. The Az values for the use of harmonic 3D power Doppler US with LRA, SVM and NN were 0.9286, 0.8979 and 0.9009, respectively. The Az values of six ROC curves for the use of LRA, SVM and NN for non-harmonic or harmonic 3D power Doppler imaging were similar. The diagnostic performances of these three models (LRA, SVM and NN) are not different as demonstrated by ROC curve analysis. Depending on user emphasis for the use of ROC curve findings, the use of LRA appears to provide better sensitivity as compared to the other statistical models

Image-optimized Coronal Magnetic Field Models

Energy Technology Data Exchange (ETDEWEB)

Jones, Shaela I.; Uritsky, Vadim; Davila, Joseph M., E-mail: shaela.i.jones-mecholsky@nasa.gov, E-mail: shaela.i.jonesmecholsky@nasa.gov [NASA Goddard Space Flight Center, Code 670, Greenbelt, MD 20771 (United States)

2017-08-01

We have reported previously on a new method we are developing for using image-based information to improve global coronal magnetic field models. In that work, we presented early tests of the method, which proved its capability to improve global models based on flawed synoptic magnetograms, given excellent constraints on the field in the model volume. In this follow-up paper, we present the results of similar tests given field constraints of a nature that could realistically be obtained from quality white-light coronagraph images of the lower corona. We pay particular attention to difficulties associated with the line-of-sight projection of features outside of the assumed coronagraph image plane and the effect on the outcome of the optimization of errors in the localization of constraints. We find that substantial improvement in the model field can be achieved with these types of constraints, even when magnetic features in the images are located outside of the image plane.

Image-Optimized Coronal Magnetic Field Models

Science.gov (United States)

Jones, Shaela I.; Uritsky, Vadim; Davila, Joseph M.

2017-01-01

We have reported previously on a new method we are developing for using image-based information to improve global coronal magnetic field models. In that work we presented early tests of the method which proved its capability to improve global models based on flawed synoptic magnetograms, given excellent constraints on the field in the model volume. In this follow-up paper we present the results of similar tests given field constraints of a nature that could realistically be obtained from quality white-light coronagraph images of the lower corona. We pay particular attention to difficulties associated with the line-of-sight projection of features outside of the assumed coronagraph image plane, and the effect on the outcome of the optimization of errors in localization of constraints. We find that substantial improvement in the model field can be achieved with this type of constraints, even when magnetic features in the images are located outside of the image plane.

Contrast Agent in Magnetic Resonance Imaging

DEFF Research Database (Denmark)

Vu-Quang, Hieu

2015-01-01

Nanoparticles have been employed as contrast agent in magnetic resonance imaging (MRI) in order to improve sensitivity and accuracy in diagnosis. In addition, these contrast agents are potentially combined with other therapeutic compounds or near infrared bio-imaging (NIR) fluorophores to obtain...... theranostic or dual imaging purposes, respectively. There were two main types of MRI contrast agent that were synthesized during this PhD project including fluorine containing nanoparticles and magnetic nanoparticles. In regard of fluorine containing nanoparticles, there were two types contrast agent...... cancer cells for cancer diagnosis in MRI. F127-Folate coated SPION were stable in various types of suspension medium for over six months. They could specifically target folate receptor of cancer cells in vitro and in vivo thus enhancing the contrast in MRI T2/T2* weighted images. These are preliminary...

Magnetic resonance imaging of hypophysis

International Nuclear Information System (INIS)

Malla Huesh, I. V.

2016-01-01

Hypothalamic-pituitary diseases represent with wide variety of symptoms in regard with changes in the endocrine function. Magnetic resonance imaging has a crucial role in detecting the morphologic appearance in physiologic conditions, malformative diseases and acquired pathologies. The MR-imaging is established as the method of choice in assessing the changes in the hypothalamic-pituitary axis. The pituitary gland is a complex structure with an important role in the homeostasis of the organism even though it is so small? It is surrounded by bony structures, vessels, nerves and the brain parenchyma. It consists of three parts - anterior called - adenohypophysis, posterior - neurohypophysis and pituitary stalk. The anterior part comprises about 75% of the gland. Computed tomography (CT) has a limited role in detecting the pituitary gland. It is mainly used in cases of elevated intracranial pressure due to suspected apoplexy. The gland's small size, relation to other structures and its soft tissue characteristic make it an accessible region of interest for detecting with MR-imaging. The lack of ionizing energy and the technical advances in the MR-methods are responsible for the creating images with better spatial resolution and signal to noise ratio. The examination is carried out on a standard protocol. It is important that thin slices are executed in sagittal and coronal planes. Performing a sequence, regarding the brain parenchyma is essential, since many malformations of the pituitary gland are associated with other congenital conditions. The examination starts with a T1W sequence to assess the normal anatomic condition of the gland. The intensity of the adenohypophysis is compared to the one in the pons. It is hypointense, whereas the neurohypophysis is hyperintense, due to the lipid neurosecretory granules transported along the hypothalamic-pituitary axis. T2W-images in coronal plane are used to evaluate the hypothalamus, pituitary stalk, optic chiasm, olfactory

Numerical study of remote detection outside the magnet with travelling wave Magnetic Resonance Imaging at 3T

International Nuclear Information System (INIS)

López, M; Vázquez, F; Solís-Nájera, S; Rodriguez, A O

2015-01-01

The use of the travelling wave approach for high magnetic field magnetic resonance imaging has been used recently with very promising results. This approach offer images one with greater field-of-view and a reasonable signal-to-noise ratio using a circular waveguide. This scheme has been proved to be successful at 7 T and 9.4 T with whole-body imager. Images have also been acquired with clinical magnetic resonance imaging systems whose resonant frequencies were 64 MHz and 128 MHz. These results motivated the use of remote detection of the magnetic resonance signal using a parallel-plate waveguide together with 3 T clinical scanners, to acquired human leg images. The cut-off frequency of this waveguide is zero for the principal mode, allowing us to overcome the barrier of transmitting waves at lower frequency than 300 MHz or 7 T for protons. These motivated the study of remote detection outside the actual magnet. We performed electromagnetic field simulations of a parallel-plate waveguide and a phantom. The signal transmission was done at 128 MHz and using a circular surface coil located almost 200 cm away for the magnet isocentre. Numerical simulations demonstrated that the magnetic field of the principal mode propagate inside a waveguide outside the magnet. Numerical results were compared with previous experimental-acquired image data under similar conditions

Evaluation of magnetic resonance velocimetry for steady flow.

Science.gov (United States)

Ku, D N; Biancheri, C L; Pettigrew, R I; Peifer, J W; Markou, C P; Engels, H

1990-11-01

Whole body magnetic resonance (MR) imaging has recently become an important diagnostic tool for cardiovascular diseases. The technique of magnetic resonance phase velocity encoding allows the quantitative measurement of velocity for an arbitrary component direction. A study was initiated to determine the ability and accuracy of MR velocimetry to measure a wide range of flow conditions including flow separation, three-dimensional secondary flow, high velocity gradients, and turbulence. A steady flow system pumped water doped with manganese chloride through a variety of test sections. Images were produced using gradient echo sequences on test sections including a straight tube, a curved tube, a smoothly converging-diverging nozzle, and an orifice. Magnetic resonance measurements of laminar and turbulent flows were depicted as cross-sectional velocity profiles. MR velocity measurements revealed such flow behavior as spatially varying velocity, recirculation and secondary flows over a wide range of conditions. Comparisons made with published experimental laser Doppler anemometry measurements and theoretical calculations for similar flow conditions revealed excellent accuracy and precision levels. The successful measurement of velocity profiles for a variety of flow conditions and geometries indicate that magnetic resonance imaging is an accurate, non-contacting velocimeter.

Presurgical mapping with magnetic source imaging. Comparisons with intraoperative findings

International Nuclear Information System (INIS)

Roberts, T.P.L.; Ferrari, P.; Perry, D.; Rowley, H.A.; Berger, M.S.

2000-01-01

We compare noninvasive preoperative mapping with magnetic source imaging to intraoperative cortical stimulation mapping. These techniques were directly compared in 17 patients who underwent preoperative and postoperative somatosensory mapping of a total of 22 comparable anatomic sites (digits, face). Our findings are presented in the context of previous studies that used magnetic source imaging and functional magnetic resonance imaging as noninvasive surrogates of intraoperative mapping for the identification of sensorimotor and language-specific brain functional centers in patients with brain tumors. We found that magnetic source imaging results were reasonably concordant with intraoperative mapping findings in over 90% of cases, and that concordance could be defined as 'good' in 77% of cases. Magnetic source imaging therefore provides a viable, if coarse, identification of somatosensory areas and, consequently, can guide and reduce the time taken for intraoperative mapping procedures. (author)

Lens-free imaging of magnetic particles in DNA assays.

Science.gov (United States)

Colle, Frederik; Vercruysse, Dries; Peeters, Sara; Liu, Chengxun; Stakenborg, Tim; Lagae, Liesbet; Del-Favero, Jurgen

2013-11-07

We present a novel opto-magnetic system for the fast and sensitive detection of nucleic acids. The system is based on a lens-free imaging approach resulting in a compact and cheap optical readout of surface hybridized DNA fragments. In our system magnetic particles are attracted towards the detection surface thereby completing the labeling step in less than 1 min. An optimized surface functionalization combined with magnetic manipulation was used to remove all nonspecifically bound magnetic particles from the detection surface. A lens-free image of the specifically bound magnetic particles on the detection surface was recorded by a CMOS imager. This recorded interference pattern was reconstructed in software, to represent the particle image at the focal distance, using little computational power. As a result we were able to detect DNA concentrations down to 10 pM with single particle sensitivity. The possibility of integrated sample preparation by manipulation of magnetic particles, combined with the cheap and highly compact lens-free detection makes our system an ideal candidate for point-of-care diagnostic applications.

Imaging Atherosclerosis with Hybrid Positron Emission Tomography/Magnetic Resonance Imaging

DEFF Research Database (Denmark)

Ripa, Rasmus Sejersten; Kjær, Andreas

2015-01-01

Noninvasive imaging of atherosclerosis could potentially move patient management towards individualized triage, treatment, and followup. The newly introduced combined positron emission tomography (PET) and magnetic resonance imaging (MRI) system could emerge as a key player in this context. Both...

Magnetic resonance imaging of central nervous system haemorrhage

International Nuclear Information System (INIS)

Silberstein, M.; Hennessy, O.

1993-01-01

The variable magnetic resonance imaging appearances of central nervous system haemorrhage, both intra- and extra-axial, are described. These will vary with the type of image contrast (T1 or T2 weighting), the nature of the imaging sequence (spin-echo or gradient-echo) and the time from onset of haemorrhage. Magnetic resonance imaging is a useful technique for imaging haemorrhage in the central nervous system as it yields temporal information about haematoma development, and it is the only non-invasive means of imaging intraspinal haemorrhage. However, in the imaging of haematomas within 24 h of onset and in subarachnoid haemorrhage computed tomography is the investigation of choice. 13 refs., 6 figs

Projection x-space magnetic particle imaging.

Science.gov (United States)

Goodwill, Patrick W; Konkle, Justin J; Zheng, Bo; Saritas, Emine U; Conolly, Steven M

2012-05-01

Projection magnetic particle imaging (MPI) can improve imaging speed by over 100-fold over traditional 3-D MPI. In this work, we derive the 2-D x-space signal equation, 2-D image equation, and introduce the concept of signal fading and resolution loss for a projection MPI imager. We then describe the design and construction of an x-space projection MPI scanner with a field gradient of 2.35 T/m across a 10 cm magnet free bore. The system has an expected resolution of 3.5 × 8.0 mm using Resovist tracer, and an experimental resolution of 3.8 × 8.4 mm resolution. The system images 2.5 cm × 5.0 cm partial field-of views (FOVs) at 10 frames/s, and acquires a full field-of-view of 10 cm × 5.0 cm in 4 s. We conclude by imaging a resolution phantom, a complex "Cal" phantom, mice injected with Resovist tracer, and experimentally confirm the theoretically predicted x-space spatial resolution.

A comparative study of colour and perfusion between two different post surgical scars. Do the laser Doppler imager and the colorimeter measure the same features of a scar?

Science.gov (United States)

Mermans, J F; Peeters, W J; Dikmans, R; Serroyen, J; van der Hulst, R R J W; Van den Kerckhove, E

2013-05-01

The purpose of this study was to investigate the influence of different located post surgical scars on both perfusion and redness. The pattern of change and correlation between perfusion and redness of post surgical scars is also examined. In this study, we measured redness and perfusion of the abdominal and breast scar of 24 women undergoing breast reconstruction with Deep Inferior Epigastric Perforator Free Flap surgery with the Minolta Chromameter CR-400/410 and the Moor Instruments laser Doppler imager 12IR, respectively, at different intervals post-operatively. The laser Doppler imager gives significantly higher values for the abdominal compared with the breast scar. There was no consistent correlation found between perfusion and redness at the different test moments for both locations. The scores of both parameters were significantly associated after 9 months follow-up for both locations. Scars closed with higher mechanical force show higher perfusion and prolonged activity; and more redness is associated with more perfusion for both post surgical scars. Nevertheless, there was no consistent correlation found between these parameters making the laser Doppler imager and the Colorimeter still non-replaceable instruments. © 2013 John Wiley & Sons A/S. Published by Blackwell Publishing Ltd.

Magnetic resonance imaging in sudden deafness

International Nuclear Information System (INIS)

Ramos, Hugo Valter Lisboa; Barros, Flavia Alencar; Penido, Norma de Oliveira; Souza, Ana Claudia Valerio de; Yamaoka, Wellington Yugo; Yamashita, Helio

2005-01-01

The etiology of sudden deafness can remain undetermined despite extensive investigation. This study addresses the value of magnetic resonance imaging in the analysis of sudden deafness patients.Study Design: transversal cohort.Material And Method: In a prospective study, 49 patients attended at otolaryngology emergency room of Federal University of Sao Paulo - Escola Paulista de Medicina, from April 2001 to May 2003, were submitted to magnetic resonance imaging.Results: Magnetic Resonance abnormalities were seen in 23 (46.9%) patients and revealed two tumors suggestive of meningioma, three vestibular schwannomas, thirteen microangiopathic changes of the brain and five (21.7%) pathological conditions of the labyrinth.Conclusion: Sudden deafness should be approached as a symptom common to different diseases. The presence of cerebellopontine angle tumors in 10.2% of our cases, among other treatable causes, justifies the recommendation of gadolinium-enhanced magnetic resonance use, not only to study the auditory peripheral pathway, but to study the whole auditory pathway including the brain. (author)

Study of the Myocardial Contraction and Relaxation Velocities through Doppler Tissue Imaging Echocardiography: A New Alternative in the Assessment of the Segmental Ventricular Function

Directory of Open Access Journals (Sweden)

Silva Carlos Eduardo Suaide

2002-01-01

Full Text Available OBJECTIVE: Doppler tissue imaging (DTI enables the study of the velocity of contraction and relaxation of myocardial segments. We established standards for the peak velocity of the different myocardial segments of the left ventricle in systole and diastole, and correlated them with the electrocardiogram. METHODS: We studied 35 healthy individuals (27 were male with ages ranging from 12 to 59 years (32.9 ± 10.6. Systolic and diastolic peak velocities were assessed by Doppler tissue imaging in 12 segments of the left ventricle, establishing their mean values and the temporal correlation with the cardiac cycle. RESULTS: The means (and standard deviation of the peak velocities in the basal, medial, and apical regions (of the septal, anterior, lateral, and posterior left ventricle walls were respectively, in cm/s, 7.35(1.64, 5.26(1.88, and 3.33(1.58 in systole and 10.56(2.34, 7.92(2.37, and 3.98(1.64 in diastole. The mean time in which systolic peak velocity was recorded was 131.59ms (±19.12ms, and diastolic was 459.18ms (±18.13ms based on the peak of the R wave of the electrocardiogram. CONCLUSION: In healthy individuals, maximum left ventricle segment velocities decreased from the bases to the ventricular apex, with certain proportionality between contraction and relaxation (P<0.05. The use of Doppler tissue imaging may be very helpful in detecting early alterations in ventricular contraction and relaxation.

Can magnetic resonance imaging differentiate undifferentiated arthritis?

DEFF Research Database (Denmark)

Østergaard, Mikkel; Duer, Anne; Hørslev-Petersen, K

2005-01-01

A high sensitivity for the detection of inflammatory and destructive changes in inflammatory joint diseases makes magnetic resonance imaging potentially useful for assigning specific diagnoses, such as rheumatoid arthritis and psoriatic arthritis in arthritides, that remain undifferentiated after...... conventional clinical, biochemical and radiographic examinations. With recent data as the starting point, the present paper describes the current knowledge on magnetic resonance imaging in the differential diagnosis of undifferentiated arthritis....

Model-based magnetization retrieval from holographic phase images

Energy Technology Data Exchange (ETDEWEB)

Röder, Falk, E-mail: f.roeder@hzdr.de [Helmholtz-Zentrum Dresden-Rossendorf, Institut für Ionenstrahlphysik und Materialforschung, Bautzner Landstr. 400, D-01328 Dresden (Germany); Triebenberg Labor, Institut für Strukturphysik, Technische Universität Dresden, D-01062 Dresden (Germany); Vogel, Karin [Triebenberg Labor, Institut für Strukturphysik, Technische Universität Dresden, D-01062 Dresden (Germany); Wolf, Daniel [Helmholtz-Zentrum Dresden-Rossendorf, Institut für Ionenstrahlphysik und Materialforschung, Bautzner Landstr. 400, D-01328 Dresden (Germany); Triebenberg Labor, Institut für Strukturphysik, Technische Universität Dresden, D-01062 Dresden (Germany); Hellwig, Olav [Helmholtz-Zentrum Dresden-Rossendorf, Institut für Ionenstrahlphysik und Materialforschung, Bautzner Landstr. 400, D-01328 Dresden (Germany); AG Magnetische Funktionsmaterialien, Institut für Physik, Technische Universität Chemnitz, D-09126 Chemnitz (Germany); HGST, A Western Digital Company, 3403 Yerba Buena Rd., San Jose, CA 95135 (United States); Wee, Sung Hun [HGST, A Western Digital Company, 3403 Yerba Buena Rd., San Jose, CA 95135 (United States); Wicht, Sebastian; Rellinghaus, Bernd [IFW Dresden, Institute for Metallic Materials, P.O. Box 270116, D-01171 Dresden (Germany)

2017-05-15

The phase shift of the electron wave is a useful measure for the projected magnetic flux density of magnetic objects at the nanometer scale. More important for materials science, however, is the knowledge about the magnetization in a magnetic nano-structure. As demonstrated here, a dominating presence of stray fields prohibits a direct interpretation of the phase in terms of magnetization modulus and direction. We therefore present a model-based approach for retrieving the magnetization by considering the projected shape of the nano-structure and assuming a homogeneous magnetization therein. We apply this method to FePt nano-islands epitaxially grown on a SrTiO{sub 3} substrate, which indicates an inclination of their magnetization direction relative to the structural easy magnetic [001] axis. By means of this real-world example, we discuss prospects and limits of this approach. - Highlights: • Retrieval of the magnetization from holographic phase images. • Magnetostatic model constructed for a magnetic nano-structure. • Decomposition into homogeneously magnetized components. • Discretization of a each component by elementary cuboids. • Analytic solution for the phase of a magnetized cuboid considered. • Fitting a set of magnetization vectors to experimental phase images.

Waveguide volume probe for magnetic resonance imaging and spectroscopy

DEFF Research Database (Denmark)

2015-01-01

The present disclosure relates to a probe for use within the field of nuclear magnetic resonance, such as magnetic resonance imaging (MRI), and magnetic resonance spectroscopy (MRS)). One embodiment relates to an RF probe for magnetic resonance imaging and/or spectroscopy comprising a conductive...... non-magnetic hollow waveguide having an internal volume and at least one open end, one or more capacitors and at least a first conductive non-magnetic wire, wherein said first conductive wire connects at least one of said one or more capacitors to opposite walls of one open end of the waveguide...

Magnetic resonance imaging in central nervous system tuberculosis

International Nuclear Information System (INIS)

Trivedi, Richa; Saksena, Sona; Gupta, Rakesh K

2009-01-01

Tuberculosis (TB) in any form is a devastating disease, which in its most severe form involves the central nervous system (CNS), with a high mortality and morbidity. Early diagnosis of CNS TB is necessary for appropriate treatment to reduce this morbidity and mortality. Routine diagnostic techniques involve culture and immunological tests of the tissue and biofluids, which are time-consuming and may delay definitive management. Noninvasive imaging modalities such as computed tomography (CT) scan and magnetic resonance imaging (MRI) are routinely used in the diagnosis of neurotuberculosis, with MRI offering greater inherent sensitivity and specificity than CT scan. In addition to conventional MRI imaging, magnetization transfer imaging, diffusion imaging, and proton magnetic resonance spectroscopy techniques are also being evaluated for better tissue characterization in CNS TB. The current article reviews the role of various MRI techniques in the diagnosis and management of CNS TB

Internal Magnetic Configuration Measured by ECE Imaging on EAST Tokamak

International Nuclear Information System (INIS)

Xu Ming; Wen Yizhi; Xie Jinlin; Yu Changxuan; Gao Bingxi; Xu Xiaoyuan; Liu Wandong; Hu Liqun; Sun Youwen; Qian Jinping; Wan Baonian

2013-01-01

ECE imaging (electron cyclotron emission imaging) is an important diagnostic which can give 2D imaging of temperature fluctuation in the core of tokamak. A method based on ECE imaging is introduced which can give the information of the position of magnetic axis and the structure of internal magnetic surface for EAST tokamak. The EFIT equilibrium reconstruction is not reliable due to the absence of important core diagnostic at the initial phase for EAST, so the information given by ECE imaging could help to improve the accuracy of EFIT equilibrium reconstruction. (magnetically confined plasma)

Magnetic particle imaging an introduction to imaging principles and scanner instrumentation

CERN Document Server

Knopp, Tobias

2012-01-01

This is an overview of recent progress in magnetic particle imaging, which uses various static and oscillating magnetic fields and tracer materials made from iron oxide nanoparticles to perform background-free measurements of the particles' local concentration.

Magnetic resonance imaging in neurologic diseases

International Nuclear Information System (INIS)

Chang, Kee Hyun; Han, Man Chung; Wan, Chu Wan; Myung, Ho Jin; Choi, Kil Soo; Ahn, Chang Beom; Oh, Chang Hyun; Cho, Zang Hee

1985-01-01

Magnetic resonance (MR) imaging with 0.15 Tesla resistive magnet developed by Korea Advanced Institute of Science were performed in 27 patients with various neurologic diseases and compared with x-ray computed tomography (CT). The purpose of the paper is to evaluate the image quality, the diagnostic value and limitation, and the optimal pulse sequence of MR imagings with a resistive magnet. The MR images were obtained by using a variety of pulse sequence with spin echo technique including saturation recovery. T2-weighted spin echo, and/or inversion recovery with various pulse repetition (TR) and echo delay (TE) times. The MR imaging demonstrated the capability of detecting the lesions shown on CT in al cases and also detected an additional finding in one case (multiple sclerosis) which was not seen on CT. The MR imaging appeared to be more useful than CT in the evaluation of syringomyelia of spinal cord and white matter disease, while it failed to demonstrated small calcific lesion or inflammatory nodule (less than 1 cm) shown on CT and has shown somewhat poor contrast resolution in the case of meingloma. The spatial resolution of saturation recovery images was similar or superior to CT, whereas the contrast resolution of saturation recovery was inferior to CT. While the saturation recovery images have shown false negative findings in 5 patients (19%), the inversion recovery and T2-weighted spin echo have shown consistently positive findings. The inversive recovery and T2-weighted spin echo images demonstrated better contrast discrimination between normal and pathologic conditions than the saturation recovery images, but somewhat poorer spatial resolution. Authors suggest that the MR images of both the saturation recovery with 300/30 and T2-weighted spin echo with 1000/90 be used as a routine procedure and additional inversion recovery of 1300/300/30 sequence as a option if white matter disease is suspected

Enhanced Methods to Estimate the Efficiency of Magnetic Nanoparticles in Imaging

Directory of Open Access Journals (Sweden)

Ann M. Hirt

2017-12-01

Full Text Available Magnetic resonance imaging (MRI and magnetic particle imaging (MPI are powerful methods in the early diagnosis of diseases. Both imaging techniques utilize magnetic nanoparticles that have high magnetic susceptibility, strong saturation magnetization, and no coercivity. FeraSpinTM R and its fractionated products have been studied for their imaging performances; however, a detailed magnetic characterization in their immobilized state is still lacking. This is particularly important for applications in MPI that require fixation of magnetic nanoparticles with the target cells or tissues. We examine the magnetic properties of immobilized FeraSpinTM R, its size fractions, and Resovist®, and use the findings to demonstrate which magnetic properties best predict performance. All samples show some degree of oxidation to hematite, and magnetic interaction between the particles, which impact negatively on image performance of the materials. MRI and MPI performance show a linear dependency on the slope of the magnetization curve, i.e., initial susceptibility, and average blocking temperature. The best performance of particles in immobilized state for MPI is found for particle sizes close to the boundary between superparamagnetic (SP and magnetically ordered, in which only Néel relaxation is important. Initial susceptibility and bifurcation temperature are the best indicators to predict MRI and MPI performance.

Magnetic resonance imaging of aneurysmal subarachnoid hemorrhage

International Nuclear Information System (INIS)

Ogawa, Toshihide; Shimosegawa, Eku; Inugami, Atsushi; Shishido, Fumio; Fujita, Hideaki; Ito, Hiroshi; Uemura, Kazuo; Yasui, Nobuyuki

1991-01-01

Magnetic resonance imaging of subarachnoid hemorrhage (SAH) due to aneurysm rupture was evaluated in relation to CT findings in nine patients. Six patients were studied within 3 days and the other three patients were studied 4 to 6 days from the ictus of SAH using a 0.5 Tesla superconducting unit. In all of the patients, hematoma in the subarachnoid space and ventricles was demonstrated by the proton density-weighted spin echo sequence, which showed that bloody cerebrospinal fluid (CSF) had a higher signal intensity than brain tissue or normal CSF. Magnetic resonance imaging was more sensitive in detecting SAH and more informative as to the site of the ruptured aneurysm than CT. Despite some limitations in applying it to patients with acute SAH, magnetic resonace imaging has clear advantages in the diagnosis of SAH. (author)

Magnetic resonance imaging of aneurysmal subarachnoid hemorrhage

Energy Technology Data Exchange (ETDEWEB)

Ogawa, Toshihide; Shimosegawa, Eku; Inugami, Atsushi; Shishido, Fumio; Fujita, Hideaki; Ito, Hiroshi; Uemura, Kazuo; Yasui, Nobuyuki (Research Inst. of Brain and Blood Vessels, Akita (Japan))

1991-11-01

Magnetic resonance imaging of subarachnoid hemorrhage (SAH) due to aneurysm rupture was evaluated in relation to CT findings in nine patients. Six patients were studied within 3 days and the other three patients were studied 4 to 6 days from the ictus of SAH using a 0.5 Tesla superconducting unit. In all of the patients, hematoma in the subarachnoid space and ventricles was demonstrated by the proton density-weighted spin echo sequence, which showed that bloody cerebrospinal fluid (CSF) had a higher signal intensity than brain tissue or normal CSF. Magnetic resonance imaging was more sensitive in detecting SAH and more informative as to the site of the ruptured aneurysm than CT. Despite some limitations in applying it to patients with acute SAH, magnetic resonace imaging has clear advantages in the diagnosis of SAH. (author).

Experimental study on blood flow patterns through the phantoms of the intracranial arterial aneurysms using color Doppler imaging

International Nuclear Information System (INIS)

Chung, Tae Sub; Jeong, Eun Kee; Rhim, Yoon Chul; Kim, Sung Bin; Lee, Dong Hoon; Kim, Dae In

1994-01-01

The occurrence, growth, thrombosis, and rupture of intracranial saccular aneurysms can be directly related to the effect of hemodynamic forces. We developed the phantom flow models and compared with the computer simulation program to analyse the flow pattern and hemodynamics that might be responsible for the intracranial arterial aneurysms. We designed the arterial phantoms of three major sites of intracranial arterial aneurysm ; 1) basilar artery tip, 2) internal carotid artery bifurcation, 3) curved area of internal carotid artery. Flow patterns in the aneurysmal portion of phantoms were evaluated with color Doppler system on the connection with automatic closed type of circulation system. Then, we compared the results with computer simulation. The hemodynamic characteristics of the phantoms were identical with those obtained by computerisation's. Three distinct zones of flow were identified by color Doppler studies on the aneurysm of the curved area of an internal carotid artery : 1) an inflow zone entering the aneurysm at the distal aspect of its orifice, 2) an outflow zone exiting the aneurysm at the proximal aspect of its orifice, 3) a central slow vortex.However, the phantoms of basilar artery tip and artery bifurcation showed a direct inflow stream at the dome of an aneurysm. Flow dynamics in the various phantoms of the aneurysms can be successfully evaluated with color Doppler imaging, and were consistent with those predicted by computer simulations

High resolution NMR imaging using a high field yokeless permanent magnet.

Science.gov (United States)

Kose, Katsumi; Haishi, Tomoyuki

2011-01-01

We measured the homogeneity and stability of the magnetic field of a high field (about 1.04 tesla) yokeless permanent magnet with 40-mm gap for high resolution nuclear magnetic resonance (NMR) imaging. Homogeneity was evaluated using a 3-dimensional (3D) lattice phantom and 3D spin-echo imaging sequences. In the central sphere (20-mm diameter), peak-to-peak magnetic field inhomogeneity was about 60 ppm, and the root-mean-square was 8 ppm. We measured room temperature, magnet temperature, and NMR frequency of the magnet simultaneously every minute for about 68 hours with and without the thermal insulator of the magnet. A simple mathematical model described the magnet's thermal property. Based on magnet performance, we performed high resolution (up to [20 µm](2)) imaging with internal NMR lock sequences of several biological samples. Our results demonstrated the usefulness of the high field small yokeless permanent magnet for high resolution NMR imaging.

High resolution NMR imaging using a high field yokeless permanent magnet

International Nuclear Information System (INIS)

Kose, Katsumi; Haishi, Tomoyuki

2011-01-01

We measured the homogeneity and stability of the magnetic field of a high field (about 1.04 tesla) yokeless permanent magnet with 40-mm gap for high resolution nuclear magnetic resonance (NMR) imaging. Homogeneity was evaluated using a 3-dimensional (3D) lattice phantom and 3D spin-echo imaging sequences. In the central sphere (20-mm diameter), peak-to-peak magnetic field inhomogeneity was about 60 ppm, and the root-mean-square was 8 ppm. We measured room temperature, magnet temperature, and NMR frequency of the magnet simultaneously every minute for about 68 hours with and without the thermal insulator of the magnet. A simple mathematical model described the magnet's thermal property. Based on magnet performance, we performed high resolution (up to [20 μm] 2 ) imaging with internal NMR lock sequences of several biological samples. Our results demonstrated the usefulness of the high field small yokeless permanent magnet for high resolution NMR imaging. (author)

Magnetic resonance imaging of chemistry.

Science.gov (United States)

Britton, Melanie M

2010-11-01

Magnetic resonance imaging (MRI) has long been recognized as one of the most important tools in medical diagnosis and research. However, MRI is also well placed to image chemical reactions and processes, determine the concentration of chemical species, and look at how chemistry couples with environmental factors, such as flow and heterogeneous media. This tutorial review will explain how magnetic resonance imaging works, reviewing its application in chemistry and its ability to directly visualise chemical processes. It will give information on what resolution and contrast are possible, and what chemical and physical parameters can be measured. It will provide examples of the use of MRI to study chemical systems, its application in chemical engineering and the identification of contrast agents for non-clinical applications. A number of studies are presented including investigation of chemical conversion and selectivity in fixed-bed reactors, temperature probes for catalyst pellets, ion mobility during tablet dissolution, solvent dynamics and ion transport in Nafion polymers and the formation of chemical waves and patterns.

A review of suspension-Scattered particles used in blood-mimicking fluid for doppler ultrasound imaging

Directory of Open Access Journals (Sweden)

Ammar A Oglat

2018-01-01

Full Text Available Doppler ultrasound imaging system description and calibration need blood-mimicking fluids (BMFs for the test target of medical ultrasound diagnostic tools, with known interior features and acoustic and physical properties of this fluid (BMF. Physical and acoustical properties determined in the International Electrotechnical Commission (IEC standard are specified as constant values, the materials used in the BMF preparation should have values similar to the IEC standard values. However, BMF is ready-made commercially from a field of medical usage, which may not be appropriate in the layout of ultrasound system or for an estimate of novel imaging mechanism. It is often eligible to have the capability to make sound properties and mimic blood arrangement for specific applications. In this review, sufficient BMF materials, liquids, and measures are described which have been generated by utilizing diverse operation mechanism and materials that have sculptured a range of biological systems.

Nuclear magnetic resonance imaging in pharmaceutical research

International Nuclear Information System (INIS)

Sarkar, S.K.

1991-01-01

Nuclear magnetic resonance imaging has important applications in pharmaceutical research since it allows specific tissue and disease characterization in animal models noninvasively with excellent anatomical resolution and therefore provides improved ability to monitor the efficacy of novel drugs. The utility of NMR imaging in renal studies to monitor the mechanism of drug action and renal function in rats is described. The extension of the resolution of an NMR image to microscopic domain at higher magnetic field strengths and the utility of NMR microimaging in cerebrovascular and tumour metastasis studies in mice are discussed. (author). 40 refs., 14 figs

Use of Doppler ultrasound for non-invasive urodynamic diagnosis

Directory of Open Access Journals (Sweden)

Hideo Ozawa

2009-01-01

Full Text Available Objectives: A totally non-invasive transperineal urodynamic technique using Doppler ultrasonography has been developed. Methods: Since normal urine does not have blood cells, urine was thought not to produce the Doppler effects. However, basic studies confirmed that the decrease of pressure at high velocity (Bernouilli effect caused dissolved gas to form microbubbles, which are detected by Doppler ultrasonography. Subjects sat and the probe was advanced via remote control to achieve gentle contact with the perineal skin. The digital uroflow data signals and the color Doppler ultrasound video images were processed on a personal computer. The flow-velocity curves from two sites; the distal prostatic urethra just above the external sphincter (V1 and the sphincteric urethra (V2 were plotted against time. The parameters of both the pressure-flow studies and the Doppler ultrasound urodynamic studies were compared in men who had various degrees of obstruction. Results: Functional cross-sectional area at prostatic urethra (A1, calculated by Q max /V1, was lower in the group of bladder outlet obstruction (BOO vs. control group. Velocity ratio (VR, which was calculated by V1/V2, was the parameter having the best correlation with BOO index, though A1 had a similar correlation. This method is viable to diagnose the degree of BOO. Conclusions: The development of non-invasive Doppler ultrasound videourodynamics (Doppler UDS will dramatically expand the information on voiding function.

Measurements of ion temperature and flow of pulsed plasmas produced by a magnetized coaxial plasma gun device using an ion Doppler spectrometer

Science.gov (United States)

Kitagawa, Y.; Sakuma, I.; Iwamoto, D.; Kikuchi, Y.; Fukumoto, N.; Nagata, M.

2012-10-01

It is important to know surface damage characteristics of plasma-facing component materials during transient heat and particle loads such as type I ELMs. A magnetized coaxial plasma gun (MCPG) device has been used as transient heat and particle source in ELM simulation experiments. Characteristics of pulsed plasmas produced by the MCPG device play an important role for the plasma material interaction. In this study, ion temperature and flow velocity of pulsed He plasmas were measured by an ion Doppler spectrometer (IDS). The IDS system consists of a light collection system including optical fibers, 1m-spectrometer and a 16 channel photomultiplier tube (PMT) detector. The IDS system measures the width and Doppler shift of HeII (468.58 nm) emission line with the time resolution of 1 μs. The Doppler broadened and shifted spectra were measured with 45 and 135 degree angles with respect to the plasmoid traveling direction. The observed emission line profile was represented by sum of two Gaussian components to determine the temperature and flow velocity. The minor component at around the wavelength of zero-velocity was produced by the stationary plasma. As the results, the ion velocity and temperature were 68 km/s and 19 eV, respectively. Thus, the He ion flow energy is 97 eV. The observed flow velocity agrees with that measured by a time of flight technique.

SQUID-Detected Magnetic Resonance Imaging in MicroteslaFields

Energy Technology Data Exchange (ETDEWEB)

Moessle, Michael; Hatridge, Michael; Clarke, John

2006-08-14

Magnetic resonance imaging (MRI) has developed into a powerful clinical tool for imaging the human body (1). This technique is based on nuclear magnetic resonance (NMR) of protons (2, 3) in a static magnetic field B{sub 0}. An applied radiofrequency pulse causes the protons to precess about B{sub 0} at their Larmor frequency {nu}{sub 0} = ({gamma}/2{pi})B{sub 0}, where {gamma} is the gyromagnetic ratio; {gamma}/2{pi} = 42.58 MHz/tesla. The precessing protons generate an oscillating magnetic field and hence a voltage in a nearby coil that is amplified and recorded. The application of three-dimensional magnetic field gradients specifies a unique magnetic field and thus an NMR frequency in each voxel of the subject, so that with appropriate encoding of the signals one can acquire a complete image (4). Most clinical MRI systems involve magnetic fields generated by superconducting magnets, and the current trend is to higher magnetic fields than the widely used 1.5-T systems (5). Nonetheless, there is ongoing interest in the development of less expensive imagers operating at lower fields. Commercially available 0.2-T systems based on permanent magnets offer both lower cost and a more open access than their higher-field counterparts, at the expense of signal-to-noise-ratio (SNR) and spatial resolution. At the still lower field of 0.03 mT maintained by a conventional, room-temperature solenoid, Connolly and co-workers (6, 7) obtain good spatial resolution and signal-to-noise ratio (SNR) by prepolarizing the protons in a field B{sub p} of 0.3 T. Prepolarization (8) enhances the magnetic moment of an ensemble of protons over that produced by the lower precession field; after the polarizing field is removed, the higher magnetic moment produces a correspondingly larger signal during its precession in B{sub 0}. Using the same method, Stepisnik et al. (9) obtained MR images in the Earth's magnetic field ({approx} 50 {micro}T). Alternatively, one can enhance the signal

A portable, low-cost, 3D-printed main magnetic field system for magnetic imaging.

Science.gov (United States)

Iksung Kang

2017-07-01

In this paper, a portable, low-cost, 3D-printed system for main magnetic field is proposed to suggest a solution for accessibility problems of current magnetic imaging systems, e.g. MRI scanner, their size and cost. The system consists of twelve pairs of NdFeB N35 permanent magnets arranged in a Halbach array in a 3D-printed, cylindrical container based on FEM simulation results by COMSOL Multiphysics 4.4b. Its magnetic field homogeneity and field strength were measured by Hall sensors, WSH-135 XPAN2 by Wilson Semiconductor, and the container was printed by 3DISON H700 by Rokit. The system generated a 5-mm imaging quality FOV and main magnetic field of 120 mT with a 12 % error in the field strength. Also, a hundred dollar was enough for the manufacture of the system with a radius of 6 cm and height of 10 cm. Given the results, I believe the system will be useful for some magnetic imaging applications, e.g. EPRI and low-field MRI.

Spectroscopic Doppler analysis for visible-light optical coherence tomography

Science.gov (United States)

Shu, Xiao; Liu, Wenzhong; Duan, Lian; Zhang, Hao F.

2017-12-01

Retinal oxygen metabolic rate can be effectively measured by visible-light optical coherence tomography (vis-OCT), which simultaneously quantifies oxygen saturation and blood flow rate in retinal vessels through spectroscopic analysis and Doppler measurement, respectively. Doppler OCT relates phase variation between sequential A-lines to the axial flow velocity of the scattering medium. The detectable phase shift is between -π and π due to its periodicity, which limits the maximum measurable unambiguous velocity without phase unwrapping. Using shorter wavelengths, vis-OCT is more vulnerable to phase ambiguity since flow induced phase variation is linearly related to the center wavenumber of the probing light. We eliminated the need for phase unwrapping using spectroscopic Doppler analysis. We split the whole vis-OCT spectrum into a series of narrow subbands and reconstructed vis-OCT images to extract corresponding Doppler phase shifts in all the subbands. Then, we quantified flow velocity by analyzing subband-dependent phase shift using linear regression. In the phantom experiment, we showed that spectroscopic Doppler analysis extended the measurable absolute phase shift range without conducting phase unwrapping. We also tested this method to quantify retinal blood flow in rodents in vivo.

Cervical myelopathy: magnetic imaging findings

International Nuclear Information System (INIS)

Kholin, A.V.; Makarov, A.Yu.; Gurevich, D.V.

1996-01-01

69 patients with clinical signs of cervical myelopathy were examined using magnetic imaging (T1- and T2-suspended tomograms of the sagittal and transverse section using a device with 0.04 T field intensity). Vertebral disk hernias were revealed in 35 patients, compression of the spinal cord with metastases into vertebral body in 2, extramedullary tumor in 11, intramedullary tumor in 9, and syringomyelia in 12 patients. T2-suspended tomograms proved to be more informative due to their higher sensitivity to aqueous content. T1-suspended tomograms help assess the degree of spinal cord compression and the direction of the disk protrusion. Magnetic imaging is an informative method used for objective identification of the cases of myelopathy of cervical localization [ru

Quantitative magnetic resonance micro-imaging methods for pharmaceutical research.

Science.gov (United States)

Mantle, M D

2011-09-30

The use of magnetic resonance imaging (MRI) as a tool in pharmaceutical research is now well established and the current literature covers a multitude of different pharmaceutically relevant research areas. This review focuses on the use of quantitative magnetic resonance micro-imaging techniques and how they have been exploited to extract information that is of direct relevance to the pharmaceutical industry. The article is divided into two main areas. The first half outlines the theoretical aspects of magnetic resonance and deals with basic magnetic resonance theory, the effects of nuclear spin-lattice (T(1)), spin-spin (T(2)) relaxation and molecular diffusion upon image quantitation, and discusses the applications of rapid magnetic resonance imaging techniques. In addition to the theory, the review aims to provide some practical guidelines for the pharmaceutical researcher with an interest in MRI as to which MRI pulse sequences/protocols should be used and when. The second half of the article reviews the recent advances and developments that have appeared in the literature concerning the use of quantitative micro-imaging methods to pharmaceutically relevant research. Copyright © 2010 Elsevier B.V. All rights reserved.

Magnetic resonance imaging of generalised musculo-skeletal diseases

International Nuclear Information System (INIS)

Kaiser, W.A.; Schalke, B.C.G.

1989-01-01

The results presented are drawn from 320 examinations by NMR imaging of patients with various systemic muscle diseases (dystrophies, myositides, metabolic disorders), and are interpreted so as to explain the relevant characteristic distribution patterns of the degenerative processes in the femoral musculature as shown by the NMR images. Four basic patterns are presented according to the criteria homogeneous-heterogeneous and symmetric-asymmetric, and the diseases identified by the differential diagnostic evaluation are discussed. The optimum measuring conditions for magnetic resonance imaging of the musculature are given, and the specific magnetic resonance criteria of myositides, neurogenic myopathies, myofonous dystrophies, c.n. polio, morbus Pompe, familial hypokalemic paralysis, centronuclear mypathy, morbus Duchenne are explained. The significance of NMR imaging with regard to biopsy or therapy planning is discussed, and magnetic resonance examination is recommended to be applied prior to biopsy. (orig.) [de

Slew-rate dependence of tracer magnetization response in magnetic particle imaging

Science.gov (United States)

Shah, Saqlain A.; Ferguson, R. M.; Krishnan, K. M.

2014-10-01

Magnetic Particle Imaging (MPI) is a new biomedical imaging technique that produces real-time, high-resolution tomographic images of superparamagnetic iron oxide nanoparticle tracers. Currently, 25 kHz and 20 mT/μ0 excitation fields are common in MPI, but lower field amplitudes may be necessary for patient safety in future designs. Here, we address fundamental questions about MPI tracer magnetization dynamics and predict tracer performance in future scanners that employ new combinations of excitation field amplitude (Ho) and frequency (ω). Using an optimized, monodisperse MPI tracer, we studied how several combinations of drive field frequencies and amplitudes affect the tracer's response, using Magnetic Particle Spectrometry and AC hysteresis, for drive field conditions at 15.5, 26, and 40.2 kHz, with field amplitudes ranging from 7 to 52 mT/μ0. For both fluid and immobilized nanoparticle samples, we determined that magnetic response was dominated by Néel reversal. Furthermore, we observed that the peak slew-rate (ωHo) determined the tracer magnetic response. Smaller amplitudes provided correspondingly smaller field of view, sometimes resulting in excitation of minor hysteresis loops. Changing the drive field conditions but keeping the peak slew-rate constant kept the tracer response almost the same. Higher peak slew-rates led to reduced maximum signal intensity and greater coercivity in the tracer response. Our experimental results were in reasonable agreement with Stoner-Wohlfarth model based theories.

Multi-color imaging of magnetic Co/Pt heterostructures

Directory of Open Access Journals (Sweden)

Felix Willems

2017-01-01

Full Text Available We present an element specific and spatially resolved view of magnetic domains in Co/Pt heterostructures in the extreme ultraviolet spectral range. Resonant small-angle scattering and coherent imaging with Fourier-transform holography reveal nanoscale magnetic domain networks via magnetic dichroism of Co at the M2,3 edges as well as via strong dichroic signals at the O2,3 and N6,7 edges of Pt. We demonstrate for the first time simultaneous, two-color coherent imaging at a free-electron laser facility paving the way for a direct real space access to ultrafast magnetization dynamics in complex multicomponent material systems.

Using Flow Characteristics in Three-Dimensional Power Doppler Ultrasound Imaging to Predict Complete Responses in Patients Undergoing Neoadjuvant Chemotherapy.

Science.gov (United States)

Shia, Wei-Chung; Huang, Yu-Len; Wu, Hwa-Koon; Chen, Dar-Ren

2017-05-01

Strategies are needed for the identification of a poor response to treatment and determination of appropriate chemotherapy strategies for patients in the early stages of neoadjuvant chemotherapy for breast cancer. We hypothesize that power Doppler ultrasound imaging can provide useful information on predicting response to neoadjuvant chemotherapy. The solid directional flow of vessels in breast tumors was used as a marker of pathologic complete responses (pCR) in patients undergoing neoadjuvant chemotherapy. Thirty-one breast cancer patients who received neoadjuvant chemotherapy and had tumors of 2 to 5 cm were recruited. Three-dimensional power Doppler ultrasound with high-definition flow imaging technology was used to acquire the indices of tumor blood flow/volume, and the chemotherapy response prediction was established, followed by support vector machine classification. The accuracy of pCR prediction before the first chemotherapy treatment was 83.87% (area under the ROC curve [AUC] = 0.6957). After the second chemotherapy treatment, the accuracy of was 87.9% (AUC = 0.756). Trend analysis showed that good and poor responders exhibited different trends in vascular flow during chemotherapy. This preliminary study demonstrates the feasibility of using the vascular flow in breast tumors to predict chemotherapeutic efficacy. © 2017 by the American Institute of Ultrasound in Medicine.

Diffusion and Perfusion Magnetic Resonance Imaging:Fundamentals and Advances

OpenAIRE

Assili, Sanam

2016-01-01

Over the past few decades, magnetic resonance imaging has been utilized as a powerful imaging modality to evaluate the structure and function of various organs in the human body,such as the brain. Additionally, diffusion and perfusion MR imaging have been increasingly used in neurovascular clinical applications. In diffusion-weighted magnetic resonance imaging, the mobility of water molecules is explored in order to obtain information about the microscopic behavior of the tissues. In contrast...

In Vivo Deep Tissue Fluorescence and Magnetic Imaging Employing Hybrid Nanostructures.

Science.gov (United States)

Ortgies, Dirk H; de la Cueva, Leonor; Del Rosal, Blanca; Sanz-Rodríguez, Francisco; Fernández, Nuria; Iglesias-de la Cruz, M Carmen; Salas, Gorka; Cabrera, David; Teran, Francisco J; Jaque, Daniel; Martín Rodríguez, Emma

2016-01-20

Breakthroughs in nanotechnology have made it possible to integrate different nanoparticles in one single hybrid nanostructure (HNS), constituting multifunctional nanosized sensors, carriers, and probes with great potential in the life sciences. In addition, such nanostructures could also offer therapeutic capabilities to achieve a wider variety of multifunctionalities. In this work, the encapsulation of both magnetic and infrared emitting nanoparticles into a polymeric matrix leads to a magnetic-fluorescent HNS with multimodal magnetic-fluorescent imaging abilities. The magnetic-fluorescent HNS are capable of simultaneous magnetic resonance imaging and deep tissue infrared fluorescence imaging, overcoming the tissue penetration limits of classical visible-light based optical imaging as reported here in living mice. Additionally, their applicability for magnetic heating in potential hyperthermia treatments is assessed.

Diagnosis of Cervical Abortion by TransvaginaI Color Doppler Sonography : A Case Report

International Nuclear Information System (INIS)

Lee, Eun Ju; Ryu, Hee Sug; Ji, Hoon; Suh, Jung Ho

1995-01-01

Cervical abortion is a spontaneous abortion of an intrauterine pregnancy into the cervical canal where the abortus is retained by a closed external os, causing distension of the cervical canal. Cervical abortion should be distinguished from the cervical pregnancy. We present a case of cervical abortion diagnosed preoperatively by transvaginal sonography and color doppler imaging, and treated by dilatation and curettage. Charateristic transvaginal sonographic findings and identification of subtrophoblastic blood flow by color doppler imaging could allow differentiation of the cevical aborition from the cervical pregnancy

Analysis of fetal movements by Doppler actocardiogram and fetal B-mode imaging.

Science.gov (United States)

Maeda, K; Tatsumura, M; Utsu, M

1999-12-01

We have presented that fetal surveillance may be enhanced by use of the fetal actocardiogram and by computerized processing of fetal motion as well as fetal B-mode ultrasound imaging. Ultrasonic Doppler fetal actogram is a sensitive and objective method for detecting and recording fetal movements. Computer processing of the actograph output signals enables powerful, detailed, and convenient analysis of fetal physiologic phenomena. The actocardiogram is a useful measurement tool not only in fetal behavioral studies but also in evaluation of fetal well-being. It reduces false-positive, nonreactive NST and false-positive sinusoidal FHR pattern. It is a valuable tool to predict fetal distress. The results of intrapartum fetal monitoring are further improved by the antepartum application of the actocardiogram. Quantified fetal motion analysis is a useful, objective evaluation of the embryo and fetus. This method allows monitoring of changes in fetal movement, as well as frequency, amplitude, and duration. Furthermore, quantification of fetal motion enables evaluation of fetal behavior states and how these states relate to other measurements, such as changes in FHR. Numeric analysis of both fetal actogram and fetal motion from B-mode images is a promising application in the correlation of fetal activity or behavior with other fetal physiologic measurements.

Magnetic resonance imaging of tablet dissolution.

Science.gov (United States)

Nott, Kevin P

2010-01-01

Magnetic resonance imaging (MRI) is the technique of choice for measuring hydration, and its effects, during dissolution of tablets since it non-invasively maps (1)H nuclei associated with 'mobile' water. Although most studies have used MRI systems with high-field superconducting magnets, low-field laboratory-based instruments based on permanent magnet technology are being developed that provide key data for the formulation scientist. Incorporation of dissolution hardware, in particular the United States Pharmacopeia (USP) apparatus 4 flow-through cell, allows measurements under controlled conditions for comparison against other dissolution methods. Furthermore, simultaneous image acquisition and measurement of drug concentration allow direct comparison of the drug release throughout the hydration process. The combination of low-field MRI with USP-4 apparatus provides another tool to aid tablet formulation. Copyright 2009 Elsevier B.V. All rights reserved.

Magnetic imaging by dichroic x-ray holography

International Nuclear Information System (INIS)

Eisebitt, S.; Loergen, M.; Eberhardt, W.; Luening, M.; Schlotter, W.F.; Stoehr, J.; Hellwig, O.

2004-01-01

Full text: While holography has evolved to a powerful technique in the visible spectral range, it is difficult to apply at shorter wavelength as no intrinsically coherent (soft) x-ray laser is available as a light source. The progression from visible light towards shorter wavelength is motivated by the increase in spatial resolution that can be achieved. Of equal importance is the possibility to exploit special contrast mechanisms provided by scattering in resonance with transitions between electronic core and valence levels. These contrast mechanisms can be utilized in x-ray holography to form a spectroscopic image of the sample, in analogy to spectromicroscopy. So far, successful x-ray spectroholography has not been reported due to the experimental difficulties associated with the short wavelength and the limited coherent photon flux available. We present images of magnetic domain patterns forming in thin film Co-Pt multilayers, obtained by spectroholography at a wavelength of 1.59 nm. At this wavelength, we exploit x ray magnetic dichroism at the Co 2p 3/2 level in a Fourier transform holography experiment. Holography at this wavelength was made possible by combining nanostructured masks with coherence l tered synchrotron radiation from an undulator source in the experimental setup. The magnetic multilayers have perpendicular anisotropy and are probed using circular polarized x-rays. Dichroic holograms are recorded by combining measurements with positive and negative helicities. The spectroholograms can be numerically inverted to show the pure magnetic sample structure, such as labyrinth or stripe domains. Currently, we achieve a spatial resolution of 100 nm in the magnetic image. The advantages and limitations of this technique will be compared to other lensless imaging techniques such as over sampling phasing. The future prospects of imaging techniques based on coherent scattering are discussed in the context of the current development of free electron x

Comparisons between PW Doppler system and enhanced FM Doppler system

DEFF Research Database (Denmark)

Wilhjelm, Jens E.; Pedersen, P. C.

1995-01-01

This paper presents a new implementation of an echo-ranging FM Doppler system with improved performance, relative to the FM Doppler system reported previously. The use of long sweeps provides a significant reduction in peak to average power ratio compared to pulsed wave (PW) emission. A PW Doppler...... system exploits the direct relationship between arrival time of the received signal and range from the transducer. In the FM Doppler systems, a similar relationship exists in the spectral domain of the demodulated received signals, so that range is represented by frequency. Thus, a shift in location...... of moving scatterers between consecutive emissions corresponds to a frequency shift in the spectral signature. The improvement relative to the earlier version of the FM Doppler system is attained by utilizing cross-correlation of real spectra rather than of magnitude spectra for assessing flow velocity...

Magnetic Resonance Imaging (MRI) -- Head

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Full Text Available Toggle navigation Test/Treatment Patient Type Screening/Wellness Disease/Condition Safety En Español More Info Images/Videos About Us News Physician Resources Professions Site Index A-Z Magnetic ...

In Vivo Imaging of Nitric Oxide by Magnetic Resonance Imaging Techniques

Directory of Open Access Journals (Sweden)

Rakesh Sharma

2014-01-01

Full Text Available Nitric oxide (NO biosensors are novel tools for real-time bioimaging of tissue oxygen changes and physiological monitoring of tissue vasculature. Nitric oxide behavior further enhances its role in mapping signal transduction at the molecular level. Spectrometric electron paramagnetic resonance (EPR and fluorometric imaging are well known techniques with the potential for in vivo bioimaging of NO. In tissues, NO is a specific target of nitrosyl compounds for chemical reaction, which provides a unique opportunity for application of newly identified NO biosensors. However, the accuracy and sensitivity of NO biosensors still need to be improved. Another potential magnetic resonance technique based on short term NO effects on proton relaxation enhancement is magnetic resonance imaging (MRI, and some NO biosensors may be used as potent imaging contrast agents for measurement of tumor size by MRI combined with fluorescent imaging. The present review provides supporting information regarding the possible use of nitrosyl compounds as NO biosensors in MRI and fluorescent bioimaging showing their measurement limitations and quantitative accuracy. These new approaches open a perspective regarding bioimaging of NO and the in vivo elucidation of NO effects by magnetic resonance techniques.

Doppler laser imaging predicts response to topical minoxidil in the treatment of female pattern hair loss.

Science.gov (United States)

McCoy, J; Kovacevic, M; Situm, M; Stanimirovic, A; Bolanca, Z; Goren, A

2016-01-01

Topical minoxidil is the only drug approved by the US FDA for the treatment of female pattern hair loss. Unfortunately, following 16 weeks of daily application, less than 40% of patients regrow hair. Several studies have demonstrated that sulfotransferase enzyme activity in plucked hair follicles predicts topical minoxidil response in female pattern hair loss patients. However, due to patients’ discomfort with the procedure, and the time required to perform the enzymatic assay it would be ideal to develop a rapid, non-invasive test for sulfotransferase enzyme activity. Minoxidil is a pro-drug converted to its active form, minoxidil sulfate, by sulfotransferase enzymes in the outer root sheath of hair. Minoxidil sulfate is the active form required for both the promotion of hair regrowth and the vasodilatory effects of minoxidil. We thus hypothesized that laser Doppler velocimetry measurement of scalp blood perfusion subsequent to the application of topical minoxidil would correlate with sulfotransferase enzyme activity in plucked hair follicles. In this study, plucked hair follicles from female pattern hair loss patients were analyzed for sulfotransferase enzyme activity. Additionally, laser Doppler velocimetry was used to measure the change in scalp perfusion at 15, 30, 45, and 60 minutes, after the application of minoxidil. In agreement with our hypothesis, we discovered a correlation (r=1.0) between the change in scalp perfusion within 60 minutes after topical minoxidil application and sulfotransferase enzyme activity in plucked hairs. To our knowledge, this is the first study demonstrating the feasibility of using laser Doppler imaging as a rapid, non-invasive diagnostic test to predict topical minoxidil response in the treatment of female pattern hair loss.

Translation compensation and micro-Doppler extraction for precession ballistic targets with a wideband terahertz radar

Science.gov (United States)

Yang, Qi; Deng, Bin; Wang, Hongqiang; Zhang, Ye; Qin, Yuliang

2018-01-01

Imaging, classification, and recognition techniques of ballistic targets in midcourse have always been the focus of research in the radar field for military applications. However, the high velocity translation of ballistic targets will subject range profile and Doppler to translation, slope, and fold, which are especially severe in the terahertz region. Therefore, a two-step translation compensation method based on envelope alignment is presented. The rough compensation is based on the traditional envelope alignment algorithm in inverse synthetic aperture radar imaging, and the fine compensation is supported by distance fitting. Then, a wideband imaging radar system with a carrier frequency of 0.32 THz is introduced, and an experiment on a precession missile model is carried out. After translation compensation with the method proposed in this paper, the range profile and the micro-Doppler distributions unaffected by translation are obtained, providing an important foundation for the high-resolution imaging and micro-Doppler extraction of the terahertz radar.

Magnetic resonance imaging of the abdomen and pelvis

International Nuclear Information System (INIS)

Anon.

1989-01-01

Magnetic resonance imaging (MRI) of the abdomen presents greater inherent difficulties than other anatomic regions. However, new techniques now allow imaging comparable in quality to computed tomography (CT). Magnetic resonance imaging offers the advantages of greater tissue contrast, multiplanar imaging, and lack of ionizing radiation or risk of toxic reactions from iodinated contrast media. Its use remains limited by high cost, limited availability, lack of a bowel contrast agent, and long imaging time, which some patients cannot tolerate. In many areas of abdominal imaging, MRI is now comparable to CT, but because of the greater availability and lesser cost, CT remains the procedure of choice. Magnetic resonance imaging is more accurate for staging neoplasms of the liver, adrenal glands, kidneys, bladder, prostate, uterus, and cervix and may aid in diagnosis of hepatic, adrenal, and uterine masses. In selected patients, especially those in whom CT is inconclusive or those who cannot tolerate iodinated contrast material, MRI can provide valuable information. Development of faster scanning techniques and MRI contrast agents and wider availability will probably increase the usefulness of abdominal MRI. At this time, MRI complements other abdominal imaging procedures. In a small number of patients, however, it can provide unique information in a virtually risk-free manner

Diagnostic accuracy of color Doppler flow imaging and Duplex US in peripheral arterial disease

International Nuclear Information System (INIS)

Karmel, M.I.; Polak, J.F.; Whittemore, A.D.; Mannick, J.A.; Donaldson, M.C.; O'Leary, D.H.

1988-01-01

Color Doppler flow imaging (5 MHz) and Duplex US were used in a prospective examination of 154 arterial segments in the lower extremities of 11 symptomatic patients. Each extremity was divided into seven arterial segments (common femoral, profunda femoral, proximal, middle, and distal superficial femoral, and proximal and distal popliteal arteries). Arterial maps were drawn for each patient and compared with the arteriograms. Seventeen significant stenoses and 18 complete occlusions were predicted and confirmed by means of arteriography. Four significant stenoses and four occlusions were predicted and not confirmed. One hundred nine normal arterial segments were correctly predicted. No significant stenoses or occlusions were missed. Prospective identification of the severity and location of disease can help to optimize both the angiographic approach and hospital services utilization

Variações de parâmetros da função diastólica do ventrículo esquerdo de acordo com a idade através da ecocardiografia com Doppler tissular Changes in the parameters of left ventricular diastolic function according to age on tissue Doppler imaging

Directory of Open Access Journals (Sweden)

Márcia Duarte Pedone

2004-12-01

Full Text Available OBJETIVO: Determinar a correlação entre as velocidades diastólicas do Doppler tissular com a idade em amostra de adultos saudáveis, e correlacionar a idade com as velocidades do fluxo transmitral e de veias pulmonares. MÉTODOS: Estudados, através da ecocardiografia, 51 indivíduos saudáveis, com idades entre 21 e 69 anos e registradas as velocidades miocárdicas diastólicas ao Doppler tissular e determinadas as velocidades dos fluxos transmitral e venoso pulmonar. RESULTADOS: As velocidades miocárdicas diastólicas iniciais septal basal e lateral basal apresentaram correlação inversa com a idade, com r = - 0,40 (p = 0,004 e r = - 0,60 (p = 0,0001 respectivamente. As velocidades atriogênicas do Doppler tissular foram diretamente correlacionadas com a idade, sendo no segmento septal basal r = 0,56 (p = 0,0001 e no segmento lateral basal r = 0,50 (p = 0,0001. As velocidades do fluxo transmitral e do fluxo venoso pulmonar também mostraram correlação com a idade. CONCLUSÃO: Existe correlação entre a idade e as velocidades miocárdicas diastólicas do Doppler tissular e com as velocidades do fluxo transmitral e fluxo venoso pulmonar, demonstrando em indivíduos saudáveis uma variação de parâmetros da função diastólica do ventrículo esquerdo com a evolução natural da idade.OBJECTIVE: To determine the correlation between diastolic velocities on tissue Doppler imaging and age in a sample of healthy adults and to correlate age with the velocities of transmitral and pulmonary vein flows. METHODS: Echocardiographic assessment of 51 healthy individuals, whose ages ranged from 21 to 69 years. The diastolic myocardial velocities were recorded on tissue Doppler imaging. The velocities of the transmitral and pulmonary vein flows were also determined. RESULTS: The initial basal septal and basal lateral diastolic myocardial velocities showed an inverse correlation with age [r = - 0.40 (P = 0.004, and r = - 0.60 (P = 0.0001, respectively

Task-oriented lossy compression of magnetic resonance images

Science.gov (United States)

Anderson, Mark C.; Atkins, M. Stella; Vaisey, Jacques

1996-04-01

A new task-oriented image quality metric is used to quantify the effects of distortion introduced into magnetic resonance images by lossy compression. This metric measures the similarity between a radiologist's manual segmentation of pathological features in the original images and the automated segmentations performed on the original and compressed images. The images are compressed using a general wavelet-based lossy image compression technique, embedded zerotree coding, and segmented using a three-dimensional stochastic model-based tissue segmentation algorithm. The performance of the compression system is then enhanced by compressing different regions of the image volume at different bit rates, guided by prior knowledge about the location of important anatomical regions in the image. Application of the new system to magnetic resonance images is shown to produce compression results superior to the conventional methods, both subjectively and with respect to the segmentation similarity metric.

Analysis of multiple scattering effects in optical Doppler tomography

DEFF Research Database (Denmark)

Yura, H.T.; Thrane, L.; Andersen, Peter E.

2005-01-01

Optical Doppler tomography (ODT) combines Doppler velocimetry and optical coherence tomography (OCT) to obtain high-resolution cross-sectional imaging of particle flow velocity in scattering media such as the human retina and skin. Here, we present the results of a theoretical analysis of ODT where...... multiple scattering effects are included. The purpose of this analysis is to determine how multiple scattering affects the estimation of the depth-resolved localized flow velocity. Depth-resolved velocity estimates are obtained directly from the corresponding mean or standard deviation of the observed...

Parallel magnetic resonance imaging

International Nuclear Information System (INIS)

Larkman, David J; Nunes, Rita G

2007-01-01

Parallel imaging has been the single biggest innovation in magnetic resonance imaging in the last decade. The use of multiple receiver coils to augment the time consuming Fourier encoding has reduced acquisition times significantly. This increase in speed comes at a time when other approaches to acquisition time reduction were reaching engineering and human limits. A brief summary of spatial encoding in MRI is followed by an introduction to the problem parallel imaging is designed to solve. There are a large number of parallel reconstruction algorithms; this article reviews a cross-section, SENSE, SMASH, g-SMASH and GRAPPA, selected to demonstrate the different approaches. Theoretical (the g-factor) and practical (coil design) limits to acquisition speed are reviewed. The practical implementation of parallel imaging is also discussed, in particular coil calibration. How to recognize potential failure modes and their associated artefacts are shown. Well-established applications including angiography, cardiac imaging and applications using echo planar imaging are reviewed and we discuss what makes a good application for parallel imaging. Finally, active research areas where parallel imaging is being used to improve data quality by repairing artefacted images are also reviewed. (invited topical review)

Development of the 1.2 T~1.5 T Permanent Magnetic Resonance Imaging Device and Its Application for Mouse Imaging

Directory of Open Access Journals (Sweden)

Guangxin Wang

2015-01-01

Full Text Available By improving the main magnet, gradient, and RF coils design technology, manufacturing methods, and inventing new magnetic resonance imaging (MRI special alloy, a cost-effective and small animal specific permanent magnet-type three-dimensional magnetic resonance imager was developed. The main magnetic field strength of magnetic resonance imager with independent intellectual property rights is 1.2~1.5 T. To demonstrate its effectiveness and validate the mouse imaging experiments in different directions, we compared the images obtained by small animal specific permanent magnet-type three-dimensional magnetic resonance imager with that obtained by using superconductor magnetic resonance imager for clinical diagnosis.

The clinical study of 2D and power doppler ultrasound in esophagus varix

International Nuclear Information System (INIS)

Li Qiang; Zhou Liang; Zhang Yucheng; Yang Minghua; Ruan Fenglian; Lu Haixia; Li Yue

2008-01-01

Objective: To study the application of 2D and Power Doppler Ultrasound in diagnosing the abdominal esophageal varicose veins. Methods: 65 patients under suspicion with chronic hepatitis and cirrhosis for esophageal varicose at esophagus in abdomen section were examined by 2D and Power Doppler Ultrasound.Among them, 35 patients suffered from esophageal varicose veins proved by gastroscopy and the rest did not. Results: On the power doppler imaging map, colored blood stream signals were showed in varicose veins while without signals in non-varicose veins.The diagnostic sensitivity and specificity were 91.4% and 100% respectively. On the two-dimensional image chart, non-echoes were represented in varicose veins. The anteroposterior diameter, right-left diameter, as well as the thickness of esophagus wall were larger in patients with varicose veins than those in non varicose veins cases (P<0.01). Conclusion: 2D combined with Power Doppler Ultrasound was of non-invasive, safe, sensitive and high specificity, which is a valuable and practical tool in diagnosing the esophageal varicose veins. (authors)

The mechanism of mid-latitude Pi2 waves in the upper ionosphere as revealed by combined Doppler and magnetometer observations

Directory of Open Access Journals (Sweden)

V. A. Pilipenko

2013-04-01

Full Text Available The interpretation of simultaneous ionospheric Doppler sounding and ground magnetometer observations of low-latitude Pi2 waves is revised. We compare the theoretical estimates of the ionospheric Doppler velocity for the same amplitude of the ground magnetic disturbances produced by a large-scale compressional mode and an Alfvén mode. The plasma vertical displacement caused by the wave electric field is shown to be the dominating effect. Taking into account the correction of the previous paper, the observations of low-latitude Pi2 in the F layer ionosphere by Doppler sounding and SuperDARN (Super Dual Auroral Radar Network radars give consistent results. We suggest that the Doppler response to Pi2 waves is produced by the Alfvén wave component, but not the fast-mode component, whereas the ground magnetic signal is composed from both Alfvén and fast magnetosonic modes.

Concordance and reproducibility between M-mode, tissue Doppler imaging, and two-dimensional strain imaging in the assessment of mitral annular displacement and velocity in patients with various heart conditions

DEFF Research Database (Denmark)

de Knegt, Martina Chantal; Biering-Sorensen, Tor; Sogaard, Peter

2014-01-01

AIMS: Mitral annular (MA) displacement reflects longitudinal left ventricular (LV) deformation and systolic velocity measurements reflect the rate of contraction; both are valuable in the diagnosis and prognosis of cardiac disease. The aim of this study was to test the agreement and reproducibility...... between motion mode (M-mode), colour tissue Doppler imaging (TDI), and two-dimensional strain imaging (2DSI) when measuring MA displacement and systolic velocity. METHODS AND RESULTS: Using GE Healthcare Vivid 7 and E9 and Echopac BT11 software, MA displacement and velocity measurements by 2DSI, TDI...

Particle image and acoustic Doppler velocimetry analysis of a cross-flow turbine wake

Science.gov (United States)

Strom, Benjamin; Brunton, Steven; Polagye, Brian

2017-11-01

Cross-flow turbines have advantageous properties for converting kinetic energy in wind and water currents to rotational mechanical energy and subsequently electrical power. A thorough understanding of cross-flow turbine wakes aids understanding of rotor flow physics, assists geometric array design, and informs control strategies for individual turbines in arrays. In this work, the wake physics of a scale model cross-flow turbine are investigated experimentally. Three-component velocity measurements are taken downstream of a two-bladed turbine in a recirculating water channel. Time-resolved stereoscopic particle image and acoustic Doppler velocimetry are compared for planes normal to and distributed along the turbine rotational axis. Wake features are described using proper orthogonal decomposition, dynamic mode decomposition, and the finite-time Lyapunov exponent. Consequences for downstream turbine placement are discussed in conjunction with two-turbine array experiments.

Children's (Pediatric) Magnetic Resonance Imaging

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Full Text Available ... MRI) exam. View full size with caption Pediatric Content Some imaging tests and treatments have special pediatric considerations. The teddy bear denotes child-specific content. Related Articles and Media Catheter Angiography Magnetic Resonance, ...

Magnetic Resonance Imaging (MRI) -- Head

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Full Text Available ... MRI) procedure View full size with caption Pediatric Content Some imaging tests and treatments have special pediatric considerations. The teddy bear denotes child-specific content. Related Articles and Media MR Angiography (MRA) Magnetic ...

Magnetic resonance imaging of vulnerable atherosclerotic plaques: current imaging strategies and molecular imaging probes

NARCIS (Netherlands)

Briley-Saebo, Karen C.; Mulder, Willem J. M.; Mani, Venkatesh; Hyafil, Fabien; Amirbekian, Vardan; Aguinaldo, Juan Gilberto S.; Fisher, Edward A.; Fayad, Zahi A.

2007-01-01

The vulnerability or destabilization of atherosclerotic plaques has been directly linked to plaque composition. Imaging modalities, such as magnetic resonance (MR) imaging, that allow for evaluation of plaque composition at a cellular and molecular level, could further improve the detection of

Color Doppler Ultrasonographic Findings of Vascular Leiomyoma: Pathologic Correlation

Energy Technology Data Exchange (ETDEWEB)

Ko, Ji Young; Koh, Sung Hye; Min, Soo Kee; Choi, A Lam; Jang, Kyung Mi; Lee, Yul; Lee, Kwan Seop; Lee, Hyun; Sohn, Jeong Hee [Hallym University Sacred Heart Hospital, Anyang (Korea, Republic of); Kim, Sam Soo [Kangwon National University College of Medicine, Chuncheon (Korea, Republic of)

2009-12-15

To evaluate the distribution of color flow signals on color Doppler ultrasonography of vascular leiomyomas and to correlate them with pathologic findings. We retrospectively analyzed color Doppler ultrasonographic images and pathologic slides of six vascular leiomyomas. We classified the patterns of distribution of color flow signals into localized compact cluster types and non-cluster types, and the pathologic findings into three subtypes: solid, venous and cavernous. All cases showed well-defined homogenous hypoechoic subcutaneous masses on gray-scale ultrasonography. Three cases showed localized compact cluster types on color Doppler ultrasonography, one in each subtype (solid, venous and cavernous). For the three non-cluster types, again there was on in each subtype. In addition, on pathologic analysis the zone of the localized compact cluster of color flow signals coincided with a cluster of larger, vascular caliber masses. Localized compact clusters of color flow signals on color Doppler ultrasonography were seen in 50% of our cases and correlated with a cluster of larger vascular caliber in the mass. But the pattern of distribution of color flows didn't show a correlation with pathologic type

Color Doppler Ultrasonographic Findings of Vascular Leiomyoma: Pathologic Correlation

International Nuclear Information System (INIS)

Ko, Ji Young; Koh, Sung Hye; Min, Soo Kee; Choi, A Lam; Jang, Kyung Mi; Lee, Yul; Lee, Kwan Seop; Lee, Hyun; Sohn, Jeong Hee; Kim, Sam Soo

2009-01-01

To evaluate the distribution of color flow signals on color Doppler ultrasonography of vascular leiomyomas and to correlate them with pathologic findings. We retrospectively analyzed color Doppler ultrasonographic images and pathologic slides of six vascular leiomyomas. We classified the patterns of distribution of color flow signals into localized compact cluster types and non-cluster types, and the pathologic findings into three subtypes: solid, venous and cavernous. All cases showed well-defined homogenous hypoechoic subcutaneous masses on gray-scale ultrasonography. Three cases showed localized compact cluster types on color Doppler ultrasonography, one in each subtype (solid, venous and cavernous). For the three non-cluster types, again there was on in each subtype. In addition, on pathologic analysis the zone of the localized compact cluster of color flow signals coincided with a cluster of larger, vascular caliber masses. Localized compact clusters of color flow signals on color Doppler ultrasonography were seen in 50% of our cases and correlated with a cluster of larger vascular caliber in the mass. But the pattern of distribution of color flows didn't show a correlation with pathologic type

Micrometer-scale magnetic imaging of geological samples using a quantum diamond microscope

Science.gov (United States)

Glenn, D. R.; Fu, R. R.; Kehayias, P.; Le Sage, D.; Lima, E. A.; Weiss, B. P.; Walsworth, R. L.

2017-08-01

Remanent magnetization in geological samples may record the past intensity and direction of planetary magnetic fields. Traditionally, this magnetization is analyzed through measurements of the net magnetic moment of bulk millimeter to centimeter sized samples. However, geological samples are often mineralogically and texturally heterogeneous at submillimeter scales, with only a fraction of the ferromagnetic grains carrying the remanent magnetization of interest. Therefore, characterizing this magnetization in such cases requires a technique capable of imaging magnetic fields at fine spatial scales and with high sensitivity. To address this challenge, we developed a new instrument, based on nitrogen-vacancy centers in diamond, which enables direct imaging of magnetic fields due to both remanent and induced magnetization, as well as optical imaging, of room-temperature geological samples with spatial resolution approaching the optical diffraction limit. We describe the operating principles of this device, which we call the quantum diamond microscope (QDM), and report its optimized image-area-normalized magnetic field sensitivity (20 µTṡµm/Hz1/2), spatial resolution (5 µm), and field of view (4 mm), as well as trade-offs between these parameters. We also perform an absolute magnetic field calibration for the device in different modes of operation, including three-axis (vector) and single-axis (projective) magnetic field imaging. Finally, we use the QDM to obtain magnetic images of several terrestrial and meteoritic rock samples, demonstrating its ability to resolve spatially distinct populations of ferromagnetic carriers.

Magnetic Resonance Imaging (MRI) -- Head

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Magnetic Resonance Imaging (MRI) -- Head

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Full Text Available ... is not harmful, but it may cause some medical devices to malfunction. Most orthopedic implants pose no ... Head? Magnetic resonance imaging (MRI) is a noninvasive medical test that physicians use to diagnose medical conditions. ...

Children's (Pediatric) Magnetic Resonance Imaging

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Full Text Available Toggle navigation Test/Treatment Patient Type Screening/Wellness Disease/Condition Safety En Español More Info Images/Videos About Us News Physician Resources Professions Site Index A-Z Children’s (Pediatric) Magnetic Resonance ...

Children's (Pediatric) Magnetic Resonance Imaging

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Full Text Available ... a risk, depending on their nature and the strength of the MRI magnet. Many implanted devices will ... full size with caption Pediatric Content Some imaging tests and treatments have special pediatric considerations. The teddy ...

Magnetic Resonance Imaging (MRI) -- Head

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Full Text Available ... a risk, depending on their nature and the strength of the MRI magnet. Many implanted devices will ... full size with caption Pediatric Content Some imaging tests and treatments have special pediatric considerations. The teddy ...

Magnetic Resonance Imaging (MRI) -- Head

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Full Text Available ... be necessary. Your doctor will explain the exact reason why another exam is requested. Sometimes a follow- ... necessary in trauma situations. Although there is no reason to believe that magnetic resonance imaging harms the ...

Magnetic Resonance Imaging (MRI) -- Head

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Full Text Available ... distort images of the facial area or brain, so you should let the radiologist know about them. ... MRI units, called short-bore systems , are designed so that the magnet does not completely surround you. ...

Children's (Pediatric) Magnetic Resonance Imaging

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Full Text Available ... distort images of the facial area or brain, so the radiologist should be aware of them. Parents ... MRI units, called short-bore systems , are designed so that the magnet does not completely surround you. ...

RAPID COMMUNICATION: Magnetic resonance imaging inside metallic vessels

Science.gov (United States)

Han, Hui; Balcom, Bruce J.

2010-10-01

We introduce magnetic resonance imaging (MRI) measurements inside metallic vessels. Until now, MRI has been unusable inside metallic vessels because of eddy currents in the walls. We have solved the problem and generated high quality images by employing a magnetic field gradient monitoring method. The ability to image within metal enclosures and structures means many new samples and systems are now amenable to MRI. Most importantly this study will form the basis of new MRI-compatible metallic pressure vessels, which will permit MRI of macroscopic systems at high pressure.

Magnetic resonance imaging of parotid tumors, 1

International Nuclear Information System (INIS)

Nakamura, Akihiko; Yamashita, Toshio; Inoue, Toshiya; Kumazawa, Tadami; Kato, Tsutomu; Sawada, Satoshi; Tanaka, Yoshimasa

1987-01-01

We compared the usefulness of magnetic resonance imaging (MRI), with that of X-ray computed tomography in the preoperative diagnosis of parotid tumors. We performed in 13 patients with parotid tumors and 10 of them were operated. The MRI equipment had a magnetic fild of 0.15 Tesla. We used the spine echo acquisition technique and a repetition time of 600, 1000 and 2000 milli-seconds, and echo time of 40 and 80 milli-seconds. We found that the T 1 weighted image well visualized the duct of the parotid gland, the T 2 weighted image provided fine pictures of the parotid tumor. The facial nerve of normal parotid glands could not be visualized by MRI. (author)

Cardiovascular imaging and image processing: Theory and practice - 1975; Proceedings of the Conference, Stanford University, Stanford, Calif., July 10-12, 1975

Science.gov (United States)

Harrison, D. C.; Sandler, H.; Miller, H. A.

1975-01-01

The present collection of papers outlines advances in ultrasonography, scintigraphy, and commercialization of medical technology as applied to cardiovascular diagnosis in research and clinical practice. Particular attention is given to instrumentation, image processing and display. As necessary concomitants to mathematical analysis, recently improved magnetic recording methods using tape or disks and high-speed computers of large capacity are coming into use. Major topics include Doppler ultrasonic techniques, high-speed cineradiography, three-dimensional imaging of the myocardium with isotopes, sector-scanning echocardiography, and commercialization of the echocardioscope. Individual items are announced in this issue.

Contrast agents in magnetic resonance imaging

International Nuclear Information System (INIS)

Karadjian, V.

1987-01-01

The origine of nuclear magnetic resonance signal is reminded and different ways for contrast enhancement in magnetic resonance imaging are presented, especially, modifications of tissus relaxation times. Investigations have focused on development of agents incorporating either paramagnetic ions or stable free radicals. Pharmacological and toxicological aspects are developed. The diagnostic potential of these substances is illustrated by the example of gadolinium complexes [fr

Pocket atlas of cranial magnetic resonance imaging

International Nuclear Information System (INIS)

Haughton, V.M.; Daniels, D.L.

1986-01-01

This atlas illustrates normal cerebral anatomy in magnetic resonance images. From their studies in cerebral anatomy utilizing cryomicrotome and other techniques, the authors selected more than 100 high-resolution images that represent the most clinically useful scans

Magnetic Resonance Imaging (MRI) -- Head

Medline Plus

Full Text Available ... an MRI scan, but this is rare. Tooth fillings and braces usually are not affected by the magnetic field, but they may distort images of the facial area or brain, so you should let the ...

Children's (Pediatric) Magnetic Resonance Imaging

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Full Text Available ... lodged in the eyes are particularly important. Tooth fillings and braces usually are not affected by the magnetic field, but they may distort images of the facial area or brain, so the radiologist should be ...

Children's (Pediatric) Magnetic Resonance Imaging

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Full Text Available ... More Info Images/Videos About Us News Physician Resources Professions Site Index A-Z Children’s (Pediatric) Magnetic ... patient to have an allergy to a gadolinium-based contrast agent used for MRI than the iodine- ...

Magnetic resonance imaging findings in patients with Hallervorden-Spatz syndrome

International Nuclear Information System (INIS)

Nomura, Cesar Higa; Lima, Eduardo Carneiro; Cerri, Giovanni Guido; Leite, Claudia da Costa; Rosemberg, Sergio

2003-01-01

The objective of this study was to review the magnetic resonance imaging findings in patients with Hallervorden-Spatz syndrome. We evaluated eight patients with Hallervorden-Spatz syndrome using magnetic resonance imaging. The protocol included at least sagittal and axial T1-weighted images and axial and coronal T2-weighted images. Intravenous gadolinium was administered in a dose of 0.1 mmol/kg. Post-enhanced images were obtained at least in the axial and coronal planes. The results were: all patients presented a bilateral and symmetrical 'tiger-eye signal' on T2-weighted images, corresponding to central hyperintensity and peripheral hypointensity in the globi pallidus. FLAIR and diffusion images showed similar abnormalities. There was no gadolinium enhancement in any of the cases. We concluded that magnetic resonance imaging findings in patients with Hallervorden-Spatz syndrome are very typical and allow the diagnosis of the disease. (author)

Transcranial magnetic stimulation assisted by neuronavigation of magnetic resonance images

Science.gov (United States)

Viesca, N. Angeline; Alcauter, S. Sarael; Barrios, A. Fernando; González, O. Jorge J.; Márquez, F. Jorge A.

2012-10-01

Technological advance has improved the way scientists and doctors can learn about the brain and treat different disorders. A non-invasive method used for this is Transcranial Magnetic Stimulation (TMS) based on neuron excitation by electromagnetic induction. Combining this method with functional Magnetic Resonance Images (fMRI), it is intended to improve the localization technique of cortical brain structures by designing an extracranial localization system, based on Alcauter et al. work.

New design on air-core resistive NMR imaging magnet

Energy Technology Data Exchange (ETDEWEB)

Chen, Yan; Mingwu, Fan; Yixin, Miao

1984-08-01

A new type of NMR imaging air-core resistive magnet is designed. Based on the BIM Magnetostatic calculation the resultant four equiradial coils structure with optimized shapes of cross section possesses a larger spherical working volume obviously, comparing with the common four-coils imaging magnet. The manufacturing tolerance is also calculated.

Magnetic Resonance Imaging (MRI) -- Head

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Full Text Available ... structures of the brain and can also provide functional information (fMRI) in selected cases. MR images of ... Articles and Media MR Angiography (MRA) Magnetic Resonance, Functional (fMRI) - Brain Head and Neck Cancer Treatment Brain ...

FIRST SIMULTANEOUS DETECTION OF MOVING MAGNETIC FEATURES IN PHOTOSPHERIC INTENSITY AND MAGNETIC FIELD DATA

International Nuclear Information System (INIS)

Lim, Eun-Kyung; Yurchyshyn, Vasyl; Goode, Philip

2012-01-01

The formation and the temporal evolution of a bipolar moving magnetic feature (MMF) was studied with high-spatial and temporal resolution. The photometric properties were observed with the New Solar Telescope at Big Bear Solar Observatory using a broadband TiO filter (705.7 nm), while the magnetic field was analyzed using the spectropolarimetric data obtained by Hinode. For the first time, we observed a bipolar MMF simultaneously in intensity images and magnetic field data, and studied the details of its structure. The vector magnetic field and the Doppler velocity of the MMF were also studied. A bipolar MMF with its positive polarity closer to the negative penumbra formed, accompanied by a bright, filamentary structure in the TiO data connecting the MMF and a dark penumbral filament. A fast downflow (≤2 km s –1 ) was detected at the positive polarity. The vector magnetic field obtained from the full Stokes inversion revealed that a bipolar MMF has a U-shaped magnetic field configuration. Our observations provide a clear intensity counterpart of the observed MMF in the photosphere, and strong evidence of the connection between the MMF and the penumbral filament as a serpentine field.

Lymphoma of uterine cervix: magnetic resonance imaging findings

Energy Technology Data Exchange (ETDEWEB)

Kanaan, Daniel; Constantino, Carolina Pesce Lamas; Souza, Rodrigo Canellas de, E-mail: daniel.kanaan@hotmail.com [Department of Radiology, Universidade Federal do Rio de Janeiro (UFRJ), RJ (Brazil); Parente, Daniella Braz [Instituto D' Or de Pesquisa e Ensino, Rio de Janeiro, RJ (Brazil)

2012-05-15

Lymphoma of the cervix is a rare disease. About 1.0% to 1.5% of extranodal lymphomas originates in the female genital tract. The clinical presentation of this condition is nonspecific and magnetic resonance imaging is important for diagnostic elucidation. The present report describes the case of a 80-year-old patient with lumbar pain, whose magnetic resonance imaging showed a large uterine mass. The final diagnosis was lymphoma. (author)

Study on Zero-Doppler Centroid Control for GEO SAR Ground Observation

Directory of Open Access Journals (Sweden)

Yicheng Jiang

2014-01-01

Full Text Available In geosynchronous Earth orbit SAR (GEO SAR, Doppler centroid compensation is a key step for imaging process, which could be performed by the attitude steering of a satellite platform. However, this zero-Doppler centroid control method does not work well when the look angle of radar is out of an expected range. This paper primarily analyzes the Doppler properties of GEO SAR in the Earth rectangular coordinate. Then, according to the actual conditions of the GEO SAR ground observation, the effective range is presented by the minimum and maximum possible look angles which are directly related to the orbital parameters. Based on the vector analysis, a new approach for zero-Doppler centroid control in GEO SAR, performing the attitude steering by a combination of pitch and roll rotation, is put forward. This approach, considering the Earth’s rotation and elliptical orbit effects, can accurately reduce the residual Doppler centroid. All the simulation results verify the correctness of the range of look angle and the proposed steering method.

Brain Imaging Using Hyperpolarized 129Xe Magnetic Resonance Imaging.

Science.gov (United States)

Chahal, Simrun; Prete, Braedan R J; Wade, Alanna; Hane, Francis T; Albert, Mitchell S

2018-01-01

Hyperpolarized (HP) 129 Xe magnetic resonance imaging (MRI) is a novel iteration of traditional MRI that relies on detecting the spins of 1 H. Since 129 Xe is a gaseous signal source, it can be used for lung imaging. Additionally, 129 Xe dissolves in the blood stream and can therefore be detectable in the brain parenchyma and vasculature. In this work, we provide detailed information on the protocols that we have developed to image 129 Xe within the brains of both rodents and human subjects. © 2018 Elsevier Inc. All rights reserved.

Acoustically modulated magnetic resonance imaging of gas-filled protein nanostructures

Science.gov (United States)

Lu, George J.; Farhadi, Arash; Szablowski, Jerzy O.; Lee-Gosselin, Audrey; Barnes, Samuel R.; Lakshmanan, Anupama; Bourdeau, Raymond W.; Shapiro, Mikhail G.

2018-05-01

Non-invasive biological imaging requires materials capable of interacting with deeply penetrant forms of energy such as magnetic fields and sound waves. Here, we show that gas vesicles (GVs), a unique class of gas-filled protein nanostructures with differential magnetic susceptibility relative to water, can produce robust contrast in magnetic resonance imaging (MRI) at sub-nanomolar concentrations, and that this contrast can be inactivated with ultrasound in situ to enable background-free imaging. We demonstrate this capability in vitro, in cells expressing these nanostructures as genetically encoded reporters, and in three model in vivo scenarios. Genetic variants of GVs, differing in their magnetic or mechanical phenotypes, allow multiplexed imaging using parametric MRI and differential acoustic sensitivity. Additionally, clustering-induced changes in MRI contrast enable the design of dynamic molecular sensors. By coupling the complementary physics of MRI and ultrasound, this nanomaterial gives rise to a distinct modality for molecular imaging with unique advantages and capabilities.

Dual-frequency magnetic particle imaging of the Brownian particle contribution

Energy Technology Data Exchange (ETDEWEB)

Viereck, Thilo, E-mail: t.viereck@tu-bs.de; Kuhlmann, Christian; Draack, Sebastian; Schilling, Meinhard; Ludwig, Frank

2017-04-01

Magnetic particle imaging (MPI) is an emerging medical imaging modality based on the non-linear response of magnetic nanoparticles to an exciting magnetic field. MPI has been recognized as a fast imaging technique with high spatial resolution in the mm range. For some applications of MPI, especially in the field of functional imaging, the determination of the particle mobility (Brownian rotation) is of great interest, as it enables binding detection in MPI. It also enables quantitative imaging in the presence of Brownian-dominated particles, which is otherwise implausible. Discrimination of different particle responses in MPI is possible via the joint reconstruction approach. In this contribution, we propose a dual-frequency acquisition scheme to enhance sensitivity and contrast in the detection of different particle mobilities compared to a standard single-frequency MPI protocol. The method takes advantage of the fact, that the magnetization response of the tracer is strongly frequency-dependent, i.e. for low excitation frequencies a stronger Brownian contribution is observed.

Ferritin protein imaging and detection by magnetic force microscopy.

Science.gov (United States)

Hsieh, Chiung-Wen; Zheng, Bin; Hsieh, Shuchen

2010-03-14

Magnetic force microscopy was used to image and detect ferritin proteins and the strength of the magnetic signal is discussed, revealing a large workable lift height between the magnetic tip and the ferritin sample.

Children's (Pediatric) Magnetic Resonance Imaging

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Full Text Available ... Magnetic Resonance Imaging Sponsored by Please note RadiologyInfo.org is not a medical facility. Please contact your ... links: For the convenience of our users, RadiologyInfo .org provides links to relevant websites. RadiologyInfo.org , ACR ...

Structural magnetic resonance imaging in epilepsy

Energy Technology Data Exchange (ETDEWEB)

Deblaere, Karel [Ghent University Hospital, Department of Neuroradiology, Ghent (Belgium); Ghent University Hospital, MR Department - 1K12, Ghent (Belgium); Achten, Eric [Ghent University Hospital, Department of Neuroradiology, Ghent (Belgium)

2008-01-15

Because of its sensitivity and high tissue contrast, magnetic resonance imaging (MRI) is the technique of choice for structural imaging in epilepsy. In this review the effect of using optimised scanning protocols and the use of high field MR systems on detection sensitivity is discussed. Also, the clinical relevance of adequate imaging in patients with focal epilepsy is highlighted. The most frequently encountered MRI findings in epilepsy are reported and their imaging characteristics depicted. Imaging focus will be on the diagnosis of hippocampal sclerosis and malformations of cortical development, two major causes of medically intractable focal epilepsy. (orig.)

Structural magnetic resonance imaging in epilepsy

International Nuclear Information System (INIS)

Deblaere, Karel; Achten, Eric

2008-01-01

Because of its sensitivity and high tissue contrast, magnetic resonance imaging (MRI) is the technique of choice for structural imaging in epilepsy. In this review the effect of using optimised scanning protocols and the use of high field MR systems on detection sensitivity is discussed. Also, the clinical relevance of adequate imaging in patients with focal epilepsy is highlighted. The most frequently encountered MRI findings in epilepsy are reported and their imaging characteristics depicted. Imaging focus will be on the diagnosis of hippocampal sclerosis and malformations of cortical development, two major causes of medically intractable focal epilepsy. (orig.)