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Sample records for macaca irus teeth

  1. Probing around implants and teeth with healthy or inflamed peri-implant mucosa/gingival. A histologic comparison in cynomolgus monkeys. (Macaca fascicularis)

    DEFF Research Database (Denmark)

    Schou, Søren; Holmstrup, Palle; Stoltze, K.

    2002-01-01

    Osseointegrated oral implants; teeth; phathology; peri-implant mucositis; gingivitis; peri-implantitis; periodontitis; diagnosis; probing depth; non-human primates; cynomolgus monkeys: Macaca fascicularis......Osseointegrated oral implants; teeth; phathology; peri-implant mucositis; gingivitis; peri-implantitis; periodontitis; diagnosis; probing depth; non-human primates; cynomolgus monkeys: Macaca fascicularis...

  2. Differences in the morphology of the maxillary sinus and roots of teeth between Macaca fuscata and Macaca fuscata yakui determined using cone beam computed tomography.

    Science.gov (United States)

    Zaizen, Tomonori; Sato, Iwao; Miwa, Yoko; Sunohara, Masataka; Yosue, Takashi; Mine, Kazuharu; Koseki, Hirohisa; Shimada, Kazuyuki

    2013-01-01

    The Japanese macaque is an endemic species consisting of two subspecies: Macaca fuscata fuscata (MFF) and Macaca fuscata yakui (MFY). The MFY is indigenous to Yakushima Island and represents a subspecies of MFF that lives from Honshu to Shikoku and Kyushu, Japan. However, the differences in the skulls of the MFY and MFF are unknown, despite these subspecies having different skull sizes. The maxillary sinus (MS) indicates that the features of the frontal view reflect the transversal growth of the maxilla of the skull. In this study, we show the MS structures of the MFF (n = 9, 18 sides) and MFY (n = 10, 20 sides) using a cone-beam computed tomography instrument. Base on three-dimensional (3D) reconstructed images the MS and nasal cavity were found to present almost to no significant differences between MFF and MFY. However, we designated three classifications of the sinus floor based on the 3D MS images of these Japanese macaques: a round-like shape (type a, MFF = 66.7% (12/18), MFY = 45% (9/20)), a flat-like shape (type b, MFF = 22.2% (4/18), MFY = 35% (7/20)), and an irregular shape (type c, MFF = 11.1% (2/18), MFY = 20.0% (4/20)). The sinus floor shapes of the MFF were mostly type a, while those of the MFY were mostly type b. The prevalence of a root contacting the cortical bone is higher in the canine (26.7%, (8/30)) and second premolar (20%, (6/30) of the MFY at the nasal cavity, moreover, this value is higher in the third molar (42.9%, (9/21)) of the MS in the MFY. These results suggest that the features of the floor of the MS are related to the differences in maxillary root apices teeth between MMF and MMF.

  3. Intrusion resistant underground structure (IRUS) : design and operations

    Energy Technology Data Exchange (ETDEWEB)

    Lange, B.A. [Atomic Energy of Canada Ltd., Chalk River, ON (Canada)

    1997-12-31

    The safety case for the IRUS low-level radioactive waste disposal facility is based on the fact that IRUS will contain three specific types of wastes only. The types of these wastes are baled wastes, bituminized incinerator ash, and bituminized reverse osmosis concentrate. IRUS will be a below-ground vault consisting of an open bottom reinforced-concrete structure (approximate dimensions 30m x 20m x 8m) with a reinforced-concrete roof. This paper covers the vault design and construction and operational features. 2 tabs.

  4. Teething

    Science.gov (United States)

    ... because this can lead to infection. Avoid teething powders. NEVER give your child aspirin or place it against the gums or teeth. DO NOT rub alcohol on your baby's gums. DO NOT use homeopathic remedies, as they ...

  5. Research and Development in Natural Language Understanding as Part of the Strategic Computing Program. Volume 3. A Guide to IRUS-II Application Development. Revision.

    Science.gov (United States)

    1990-10-01

    Section 26 4.2.1 Variable Binding List 26 4.2.2 [Rule Body 27 4.2.3 IRule Examples 28 4.3 Creating !Rules 30 4.3.1 Using IRACQ 30 4.3.2 An IRACQ session...representing a user’s input) i; addition contains fields for the parse tree, WML, discourse entities, and anaphor resolution information for that input...more than one possible referent is found for an anaphor , the options are presented to the user, who indicates which to use. 2.2 IRUS-II Capabilities

  6. Craniodental variation among Macaques (Macaca, nonhuman primates

    Directory of Open Access Journals (Sweden)

    Pan Ruliang

    2002-05-01

    Full Text Available Abstract Background In terms of structure and function, the skull is one of the most complicated organs in the body. It is also one of the most important parts in terms of developmental and evolutionary origins. This complexity makes it difficult to obtain evolutionary assessments if, as is usually the case with fossils, only part of the skull is available. For this reason this study involves a set of comparisons whereby the smallest functional units are studied first, and these built up, through a triple-nested hierarchical design, into more complex anatomical regions and eventually into the skull-as-a-whole. This design has been applied to macaques (Macaca in order to reveal patterns of variation at the different levels. The profiles of such variation have been obtained both within and between species. This has lead to a search for the skull parts that have undergone similar selection pressures during evolution and comparable development patterns in both ontogeny and phylogeny. Results Morphometric analysis (Principal Components was used to obtain these profiles of species and sex separations based on 77 cranial variables from 11 species of macaques. The results showed that 7 functional units could be aggregated into three functionally reasonable anatomical regions on the basis of similarities in profiles. These were: the masticatory apparatus containing mandible, lower teeth and upper teeth, the face as a whole combining maxilla (actually lower face and upper face, and the cranium as a whole involving cranium and calvaria. Twenty-six variables were finally selected for analyzing the morphology of the whole skull. This last showed an overall profile similar to that revealed in the masticatory apparatus but also contained additional information pertaining to individual species and species-groups separations. Conclusions The study provides a model for carrying out analysis of species separations and sex variation simultaneously. Through this

  7. False Teeth

    African Journals Online (AJOL)

    FOMCS2

    More than 80% of the respondents used traditional medicine alone or in combination with modern .... Table 2. Perceived causes of false teeth and millet disease in Bushenyi district ..... “Killer” canine removal and its sequelae in Addis Ababa.

  8. Teething Tots

    Science.gov (United States)

    ... some may seem cranky for weeks, with crying spells and disrupted sleeping and eating patterns. Teething can ... it can't break into small pieces. A wet washcloth placed in the freezer for 30 minutes ...

  9. Finnegan's teeth

    OpenAIRE

    Cowan, Judith

    2009-01-01

    Finnegan's Teeth is a visual journey seen through the eyes of the animal, Finnegan. Taking place around King's Cross in London, it follows the area as it goes through construction and deconstruction. Photographs of the happenings and events that Finnegan notices on his travels accompany the voices of the street life around him. Finnegan's Teeth is the title of a recently published book by artist Judith Cowan, which has now developed into a major public Art project. This takes Finnegan's ...

  10. Pediculosis in Macaca sylvanus of Gibraltar.

    Science.gov (United States)

    Cohn, Douglas L; Smith, Vincent; Pizarro, Mark; Jones-Engel, Lisa; Engel, Gregory; Fuentes, Agustin; Shaw, Eric; Cortes, John

    2007-04-10

    Pedicinus spp. parasitize several species of nonhuman primates. This is the first published report confirming the presence of Pedicinus albidus (Rudow) infestation in the free-ranging macaques (Macaca sylvanus) of Gibraltar. The diagnosis of pediculosis was based upon finding adult lice on host animals.

  11. Prototype Abstraction by Monkeys ("Macaca Mulatta")

    Science.gov (United States)

    Smith, J. David; Redford, Joshua S.; Haas, Sarah M.

    2008-01-01

    The authors analyze the shape categorization of rhesus monkeys ("Macaca mulatta") and the role of prototype- and exemplar-based comparison processes in monkeys' category learning. Prototype and exemplar theories make contrasting predictions regarding performance on the Posner-Homa dot-distortion categorization task. Prototype theory--which…

  12. Wisdom Teeth Management

    Science.gov (United States)

    Wisdom Teeth Management Wisdom teeth, or third molars, are the last teeth to develop and appear in your mouth. They come ... of third molars, disease status, and to suggest management options ranging from removal to a monitored retention ...

  13. Wisdom Teeth Management

    Science.gov (United States)

    Wisdom Teeth Management Wisdom teeth, or third molars, are the last teeth to develop and appear in your mouth. They come ... of third molars, disease status, and to suggest management options ranging from removal to a monitored retention ...

  14. ESTHETICS IN PRIMARY TEETH

    National Research Council Canada - National Science Library

    Mathew Renu Ann

    2013-01-01

    .... Esthetic restoration of primary anterior teeth can be especially challenging due to the small size of the teeth, close proximity of pulp to tooth surface, relatively thin enamel and surface area...

  15. Hepatitis G virus genomic RNA is pathogenic to Macaca mulatta

    Institute of Scientific and Technical Information of China (English)

    Hao Ren; Fen-Lu Zhu; Ming-Mei Cao; Xin-Yu Wen; Ping Zhao; Zhong-Tian Qi

    2005-01-01

    AIM: To explore the pathogenicity and infectivity of hepatitis G virus (HGV) by observing replication and expression of the virus, as well as the serological and histological changes of Macaca mulatta infected with HGV genomic RNA or HGV RNA-positive serum.METHODS: Full-length HGV cDNA clone (HGVqz) was constructed and proved to be infectious, from which HGV genomic RNA was transcribed in vitro. Macaca mulatta BY1 was intra-hepatically inoculated with HGV genomic RNA, HGV RNA-positive serum from BY1 was intravenously inoculated into Macaca mulatta BM1, and then BB1 was infected with serum from BM1. Serum and liver tissue were taken regularly, and checked with RT-PCR, in situ hybridization and other immunological, serological,histological assays.RESULTS: Serum HGV RNA was detectable in all the 3Macaca mulattas, serological and histological examinations showed the experimental animals had slightly elevated alanine transaminase (ALT) and developed HGV viremia during the infectious period. The histology, immunohistochemistry, and in situ hybridization in liver tissues of the inoculated animals demonstrated a very mild hepatitis with HGV antigen expression in cytoplasm of hepatocytes.RT-PCR and quantitative PCR results showed that HGV could replicate in liver.CONCLUSION: The genomic RNA from full-length HGV cDNA is infectious to the Macaca mulatta and can cause mild hepatitis. HGV RNA-positive serum, from HGV RNA inoculated Macaca mulatta, is infectious to other Macaca mulattas. Macaca mulatta is susceptible to the inoculated HGV, and therefore can be used as an experimental animal model for the studies of HGV infection and pathogenesis.

  16. Can Monkeys (Macaca mulatta) Represent Invisible Displacement?

    Science.gov (United States)

    Filion, Christine M.; Washburn, David A.; Gulledge, Jonathan P.

    1996-01-01

    Four experiments were conducted to assess whether or not rhesus macaques (Macaca mulatta) could represent the unperceived movements of a stimulus. Subjects were tested on 2 computerized tasks, HOLE (monkeys) and LASER (humans and monkeys), in which subjects needed to chase or shoot at, respectively, a moving target that either remained visible or became invisible for a portion of its path of movement. Response patterns were analyzed and compared between target-visible and target-invisible conditions. Results of Experiments 1, 2, and 3 demonstrated that the monkeys are capable of extrapolating movement. That this extrapolation involved internal representation of the target's invisible movement was suggested but not confirmed. Experiment 4, however, demonstrated that the monkeys are capable of representing the invisible displacements of a stimulus.

  17. Osseointegration of dental implants in Macaca fascicularis

    Science.gov (United States)

    Dewi, R. S.; Odang, R. W.; Odelia, L.

    2017-08-01

    Osseointegration is an important factor in determining the success of a dental implant. It can be assessed from the osseointegration that occurs between the implant and the bone. The implant stability is determined by the osseous support at the implant-bone interface, which is commonly evaluated by histomorphometric analysis. This study aimed to evaluate whether the osseointegration level measured by a Low Resonance Frequency Analyzer (LRFA) gave results as good as those obtained by histomorphometric examination. Six male Macaca fascicularis were used in this study. In each animal, two types of loading were performed: immediate and delayed loading. Clinical examination and LRFA measurement were performed to determine osseointegration at the first and second weeks and at the first, second, third, and fourth months. After four months, histomorphometric examination was performed. The relationship between the histomorphometric examination and LRFA measurement was compared using the Pearson correlation coefficient. There was no significant difference in the osseointegration between immediate loading and delayed loading (p > 0.05) The bone-implant contact percentage in the first group did not differ significantly from that in the second group. Statistical analysis showed that there was a strong correlation between LRFA measurement and histomorphometric examination. Osseointegration could be evaluated through LRFA measurement as well as through histomorphometric examination.

  18. Malocclusion of teeth

    Science.gov (United States)

    ... clean and decrease risk of tooth decay and periodontal diseases ( gingivitis or periodontitis ). Eliminate strain on the teeth, ... JA, ed. McDonald and Avery's Dentistry for the Child and Adolescent . 10th ed. St. Louis, MO: Elsevier; 2016:chap ...

  19. Supernumerary teeth in clinical practice

    Directory of Open Access Journals (Sweden)

    Anna K. Szkaradkiewicz

    2011-07-01

    Full Text Available Introduction: Hyperdontia is the condition of having supernumerary teeth, or teeth which appear in addition to the regular number of teeth. The prevalence rates of supernumerary teeth in the permanent dentition amounts 0.1-6.9%, and in deciduous dentition 0.4-0.8%. The presence of supernumerary teeth can be found in everyday dental practice.Case presentation: We describe 3 cases of patients with supernumerary teeth. First patient had supernumerary lateral incisor 12s, second - premolar fused, multicuspid, supernumerary deciduous tooth 64s of having several interconnected roots, and third - erupted odontoma between teeth 13 and 14. In all cases treatment involved the removal of the supernumerary tooth.Conclusions: The decision on proceeding with the supernumerary teeth should be based on the full clinical picture and interview. Early diagnosis and removal of supernumerary teeth allow to avoid or reduce possible complications.

  20. Estimating Gear Teeth Stiffness

    DEFF Research Database (Denmark)

    Pedersen, Niels Leergaard

    2013-01-01

    The estimation of gear stiffness is important for determining the load distribution between the gear teeth when two sets of teeth are in contact. Two factors have a major influence on the stiffness; firstly the boundary condition through the gear rim size included in the stiffness calculation...... and secondly the size of the contact. In the FE calculation the true gear tooth root profile is applied. The meshing stiffness’s of gears are highly non-linear, it is however found that the stiffness of an individual tooth can be expressed in a linear form assuming that the contact length is constant....

  1. Malocclusion (Misaligned Teeth)

    Science.gov (United States)

    ... More Information Medical Dictionary Also of Interest (Quiz) Biology of the Mouth (Video) Root Canal Additional Content Medical News Malocclusion ˌmal-ə-ˈklü-zhən (Misaligned Teeth) By David F. Murchison, DDS, MMS, Clinical Professor, Department of Biological Sciences;Clinical Professor, The University ...

  2. Management of supernumerary teeth

    Directory of Open Access Journals (Sweden)

    Abhishek Parolia

    2011-01-01

    Full Text Available Supernumerary paramolars are the rare anomalies of the maxillofacial complex. These are more common in the maxilla than in the mandible. This article reviews the etiology, frequency, classification, complications, diagnosis and management of supernumerary teeth (bilateral maxillary paramolars

  3. About Kids' Teeth

    Science.gov (United States)

    ... “smile insurance.” Baby Tooth Decay Baby Tooth Decay Is Real As soon as teeth appear in ... of a mouth appliance. Prevent Decay Prevent Kids’ Tooth Decay You can prevent tooth decay for your kids ...

  4. Snow-white teeth

    National Research Council Canada - National Science Library

    Sarll, D

    2006-01-01

    ... well have pointed out, but unavailingly, that snow-white teeth adorn only the grins of infants.There is, however, another ploy that colleagues might try in their quest to enlighten patients, particularly those of a literary disposition: adduce the attributes of 'youthful beauty' given to us by Virginia Woolf (1882 - 1941). From her novel, Orla...

  5. Mouth and Teeth (For Parents)

    Science.gov (United States)

    ... Reading Is Your Child Too Busy? Helping Your Child Adjust to Preschool School Lunches Kids and Food: ... in this article? Basic Anatomy of the Mouth and Teeth Normal Development of the Mouth and Teeth What the Mouth ...

  6. Rhesus monkeys (Macaca mulatta) map number onto space

    OpenAIRE

    Drucker, Caroline B.; Brannon, Elizabeth M.

    2014-01-01

    Humans map number onto space. However, the origins of this association, and particularly the degree to which it depends upon cultural experience, are not fully understood. Here we provide the first demonstration of a number-space mapping in a non-human primate. We trained four adult male rhesus macaques (Macaca mulatta) to select the fourth position from the bottom of a five-element vertical array. Monkeys maintained a preference to choose the fourth position through changes in the appearance...

  7. [Multiple retained deciduous teeth: a case report].

    Science.gov (United States)

    Wang, Jing; Lai, Wen-Li

    2009-06-01

    Retained deciduous teeth are defined as the succedaneous permanent teeth have erupted while the primary teeth were retained, or the permanent teeth unerupted while the primary teeth remained in the permanent dentition. One case of multiple retained deciduous teeth was reported.

  8. [Infants wearing teething necklaces].

    Science.gov (United States)

    Taillefer, A; Casasoprana, A; Cascarigny, F; Claudet, I

    2012-10-01

    Numerous infants wear teething necklaces, a quack remedy with a real risk of strangulation or aspiration of small beads. Evaluate parental perceptions and beliefs about the use of teething necklaces and analyze parental knowledge about the associated dangers. Between March and July 2011, in three different pediatric units of a tertiary children's hospital and a general hospital in Toulouse and Montauban (southwest France), voluntary parents were invited to be interviewed about their child wearing a teething necklace. The interviews were conducted following an anthropological approach: they were recorded and then fully transcribed and analyzed. Parents were informed that the conversation was recorded. During the study period, 48 children were eligible. Eleven families refused to participate, 29 parents were interviewed face to face. The children's mean age was 14 years ± 7 months, the male:female ratio was equal to 0.8 (12 boys, 15 girls). The mean age of children when necklace wearing was started was equal to 4 ± 2 months. The mean mother's age was 31 ± 5 years and 33 ± 4 years for fathers. The parents' religion was mostly Catholic (60%). Teething necklaces were mainly made of amber (n=23). Sales information about the risks associated with the necklaces was for the most part absent (92%). The most frequent positive parental perceptions were analgesic properties and a soothing remedy (73%); a birth accessory and memory (64%); an esthetic accessory (60%); a protective amulet (60%); and an alternative or additional element to other traditional therapeutics (55%). The negative parental perceptions (n=4) were an unnecessary accessory, costume jewelry, a pure commercial abuse of a popular belief, a dangerous item with a risk of strangulation, and the absence of proof of its efficacy. Although parents concede that teeth eruption is benign, they fear its related symptoms. To a natural phenomenon a natural response: they use a necklace to satisfy the analogy. The

  9. New teeth from old: treatment options for retained primary teeth.

    Science.gov (United States)

    Robinson, S; Chan, M F W-Y

    2009-10-10

    Retention of primary teeth beyond their expected exfoliation date is encountered relatively frequently. Most commonly this is due to absence of the permanent successor. In this article patient assessment and the restorative treatment options are discussed with particular emphasis on retention of the primary tooth/teeth in the medium to long-term. The restorative techniques that may be used to improve aesthetics and function of retained primary teeth are illustrated. Consideration of this minimally invasive approach is commended in such cases.

  10. Management of multiple impacted teeth

    Directory of Open Access Journals (Sweden)

    Nidhi Bansal

    2012-01-01

    Full Text Available An impacted or missing permanent tooth can add significant complications to an otherwise straightforward case. When multiple impacted teeth are present, the case complexity increases further. Developing a treatment sequence, determining appropriate anchorage, and planning and executing sound biomechanics can be a challenge. The following case report illustrates a patient with three retained primary teeth and three impacted permanent canines. After careful treatment planning and extraction of multiple primary teeth;, followed by attempted guided eruption of impacted teeth, the patient finished with a significantly improved functional and aesthetic result.

  11. Keeping Your Child's Teeth Healthy

    Science.gov (United States)

    ... options than ever. A silver-colored material called amalgam (a special mix of metals) was once the substance of choice for most fillings in permanent teeth. But now, other materials like composite resins are becoming popular. Resins bond to the teeth ...

  12. Fructosamine reference ranges in rhesus macaques (Macaca mulatta).

    Science.gov (United States)

    Williams-Fritze, Misty J; Smith, Peter C; Zelterman, Daniel; Scholz, Jodi A Carlson

    2011-07-01

    Naturally occurring diabetes mellitus (DM) is common in several species of Old and New World nonhuman primates. Fructosamine values provide important information about recent glycemic control and can be useful in the diagnosis and management of DM. However, despite an abundance of reports in the literature describing spontaneous and induced DM in monkeys, few reference ranges are available for fructosamine. Reference ranges have been published for woolly monkeys (Lagothrix lagotricha), cynomolgus macaques (Macaca fascicularis), and stumptail macaques (Macaca arctoides) but currently are not available for rhesus macaques. At our institution, DM is a common diagnosis in aging rhesus macaques. Here we report a reference range for fructosamine in rhesus macaques. The overall range was 157 to 230 μmol/L, with male rhesus and macaques 10 y or older having significantly higher values than do female rhesus and macaques younger than 10 y, respectively. This range provides clinical veterinarians with an additional tool for evaluating glycemic control in rhesus macaques. Copyright 2011 by the American Association for Laboratory Animal Science

  13. Triple Teeth: Report of an Unusual Case

    OpenAIRE

    Prashant Babaji; M. A. Prasanth; Gowda, Ajith R.; Soumya Ajith; Henston D'Souza; Ashok, K. P.

    2012-01-01

    Fusion or synodontia is a union of two or more than two developing teeth. Commonly fusion occurs between teeth of the same dentition, mixed dentition, or between normal and supernumerary teeth. Fused primary teeth present with several clinical problems like caries, periodontal problem, arch asymmetry, delayed eruption, ectopic eruption of succedaneous teeth, aesthetic, and other complications. This paper presents a rare and unusual case of triple teeth in mandibular primary dentition.

  14. Triple Teeth: Report of an Unusual Case

    Directory of Open Access Journals (Sweden)

    Prashant Babaji

    2012-01-01

    Full Text Available Fusion or synodontia is a union of two or more than two developing teeth. Commonly fusion occurs between teeth of the same dentition, mixed dentition, or between normal and supernumerary teeth. Fused primary teeth present with several clinical problems like caries, periodontal problem, arch asymmetry, delayed eruption, ectopic eruption of succedaneous teeth, aesthetic, and other complications. This paper presents a rare and unusual case of triple teeth in mandibular primary dentition.

  15. Biologic data of Macaca mulatta, Macaca fascicularis, and Saimiri sciureusused for research at the fiocruz primate center

    Directory of Open Access Journals (Sweden)

    Márcia Cristina Ribeiro Andrade

    2004-10-01

    Full Text Available Physiological parameters of laboratory animals used for biomedical research is crucial for following several experimental procedures. With the intent to establish baseline biologic parameters for non-human primates held in closed colonies, hematological and morphometric data of captive monkeys were determined. Data of clinically healthy rhesus macaques (Macaca mulatta, cynomolgus monkeys (Macaca fascicularis, and squirrel monkeys (Saimiri sciureus were collected over a period of five years. Animals were separated according to sex and divided into five age groups. Hematological data were compared with those in the literature by Student's t test. Discrepancies with significance levels of 0.1, 1 or 5% were found in the hematological studies. Growth curves showed that the sexual dimorphism of rhesus monkeys appeared at an age of four years. In earlier ages, the differences between sexes could not be distinguished (p < 0.05. Sexual dimorphism in both squirrel monkeys and cynomolgus monkeys occurred at an age of about 32 months. Data presented in this paper could be useful for comparative studies using primates under similar conditions.

  16. Pharmacokinetics of Cefovecin in Cynomolgus Macaques (Macaca fascicularis), Olive Baboons (Papio anubis), and Rhesus Macaques (Macaca mulatto)

    Energy Technology Data Exchange (ETDEWEB)

    Raabe, Brigitte M.; Lovaglio, Jamie A.; Grover, GScott; Brown, Scott A.; Boucher, Joseph F.; Yuan, Yang; Civil, Jacqueline R.; Gillhouse, Kimberly A.; Stubbs, Makeida N.; Hoggatt, Amber F.; Halliday, Lisa C.; Fortman, Jeffrey D.

    2011-05-01

    Cefovecin sodium is a long-acting, third-generation, cephalosporin antibiotic approved for the treatment of skin infections in dogs and cats. The pharmacokinetic properties of cefovecin were evaluated in cynomolgus macaques (Macaca fascicularis), olive baboons (Papio anubis), and rhesus macaques (Macaca mulatto) by using a single-dose (8 mg/kg SC) dosing regimen. Plasma cefovecin concentrations were determined by using ultra-performance liquid chromatography with tandem mass spectrometry, and a noncompartmental model was used to determine pharmacokinetic parameters. The half-life of cefovecin was 4.95 {+-} 1.47 h in cynomolgus macaques, 9.17 {+-} 1.84 h in olive baboons, and 8.40 {+-} 2.53 h in rhesus macaques. These values are considerably lower than the half-lives previously published for dogs (133 h) and cats (166 h). The extended half-life of cefovecin in dogs and cats is speculated to be due to active reabsorption of drug in the kidney tubules because plasma clearance is well below the normal glomerular filtration rate. In nonhuman primates, renal clearance rates approximated plasma clearance rates, suggesting that active renal reabsorption of cefovecin does not occur in these species. The pharmacokinetic properties of cefovecin in nonhuman primates are vastly different from the pharmacokinetic properties in dogs and cats, precluding its use as a long-acting antibiotic in nonhuman primates. This study highlights the importance of performing pharmacokinetic studies prior to extralabel drug usage.

  17. Supernumerary Teeth in Nepalese Children

    Directory of Open Access Journals (Sweden)

    Varun Pratap Singh

    2014-01-01

    Full Text Available Objective. The objectives of the present study were to investigate the prevalence and characteristics of supernumerary teeth in a patient sample of Nepalese children. Study Design. A survey was performed on 2684 patients (1829 females and 1035 males ranging in age from 6 to 14 for the presence of supernumerary teeth. For each patient with supernumerary teeth the demographic variables (age and sex, number, location, eruption status, and morphology were recorded. Descriptive statistics were performed. Results. Supernumerary teeth were detected in 46 subjects (1.6%, of which 26 were males and 20 were females with a male : female ratio of 1.3 : 1. The most commonly found supernumerary tooth was mesiodens followed by maxillary premolars, maxillary lateral incisor, and mandibular lateral incisor. Of the 55 supernumerary teeth examined, 58.18% (n=32 had conical morphology, followed by tuberculate (30.90%, n=17 and supplemental (10.90%, n=6 forms. The majority of the supernumerary teeth were erupted (56.36%, n=31. Conclusion. The prevalence of supernumerary teeth in Nepalese children was found to be 1.6%, the most frequent type being mesiodens. Conical morphology was found to be the most common form of supernumerary tooth.

  18. Supernumerary teeth in Nepalese children.

    Science.gov (United States)

    Singh, Varun Pratap; Sharma, Amita; Sharma, Sonam

    2014-01-01

    The objectives of the present study were to investigate the prevalence and characteristics of supernumerary teeth in a patient sample of Nepalese children. A survey was performed on 2684 patients (1829 females and 1035 males) ranging in age from 6 to 14 for the presence of supernumerary teeth. For each patient with supernumerary teeth the demographic variables (age and sex), number, location, eruption status, and morphology were recorded. Descriptive statistics were performed. Supernumerary teeth were detected in 46 subjects (1.6%), of which 26 were males and 20 were females with a male : female ratio of 1.3 : 1. The most commonly found supernumerary tooth was mesiodens followed by maxillary premolars, maxillary lateral incisor, and mandibular lateral incisor. Of the 55 supernumerary teeth examined, 58.18% (n = 32) had conical morphology, followed by tuberculate (30.90%, n = 17) and supplemental (10.90%, n = 6) forms. The majority of the supernumerary teeth were erupted (56.36%, n = 31). The prevalence of supernumerary teeth in Nepalese children was found to be 1.6%, the most frequent type being mesiodens. Conical morphology was found to be the most common form of supernumerary tooth.

  19. A case of congenital absence of numerous primary teeth treated with a denture for deciduous teeth

    OpenAIRE

    向井, 綾子; MUKAI, AYAKO

    2015-01-01

    Anomalies of the number of teeth include anodontia. The congenital absence of all teeth is called complete anodontia, and that of several teeth is called partial anodontia. Agenesis of numerous teeth causes a decrease in mastication and esthetic problems, and its treatment is often difficult.In the present paper, we report the case of a partial anodontia patient congenitally missing 6 primary teeth and some permanent teeth. The patient was treated using a denture for deciduous teeth to improv...

  20. Restoring primary anterior teeth.

    Science.gov (United States)

    Waggoner, William F

    2002-01-01

    A variety of esthetic restorative materials are available for restoring primary incisors. Knowledge of the specific strengths, weakness, and properties of each material will enhance the clinician's ability to make the best choice of selection for each individual situation. Intracoronal restorations of primary teeth may utilize resin composites, glass ionomer cements, resin-modified ionomers, or polyacid-modified resins. Each has distinct advantages and disadvantages and the clinical conditions of placement may be a strong determining factor as to which material is utilized. Full coronal restoration of primary incisors may be indicated for a number of reasons. Crowns available for restoration of primary incisors include those that are directly bonded onto the tooth, which generally are a resin material, and those crowns that are luted onto the tooth and are some type of stainless steel crown. However, due to lack of supporting clinical data, none of the crowns can be said to be superior to the others under all circumstances. Though caries in the mandibular region is rare, restorative solutions for mandibular incisors are needed. Neither stainless steel crowns nor celluloid crown forms are made specifically for mandibular incisors. Many options exist to repair carious primary incisors, but there is insufficient controlled, clinical data to suggest that one type of restoration is superior to another. This does not discount the fact that dentists have been using many of these crowns for years with much success. Operator preferences, esthetic demands by parents, the child's behavior, and moisture and hemorrhage control are all variables which affect the decision and ultimate outcome of whatever restorative treatment is chosen.

  1. Variation in Clitoral Length in Rhesus Macaques (Macaca mulatta)

    Science.gov (United States)

    Goldschmidt, Beatriz; Cabello, Pedro H; Kugelmeier, Tatiana; Pereira, Barbara B; Lopes, Claudia A; Fasano, Daniele M; Andrade, Marcia C; Santos, Joice S; Marinho, Antonio M

    2009-01-01

    Clitoromegaly in the neonatal period is an important morphologic sign that can be useful for sexual determination in aberrant cases. In rhesus monkeys, differentiation of the external genitalia occurs early during gestation (at 55 to 60 d) and is complete by approximately 80 d. Most of the critical steps in genital differentiation in primates occur prenatally. We sought to determine clitoral size in normal rhesus monkeys (Macaca mulatta) and possible effects of age and inheritance. Clitoral length was highly variable and had no relationship to fertility. Statistical evaluation revealed no association in the distribution of daughters with and without clitoris between mothers with and without clitoris. However, even when mated with several female monkeys, some male macaques produced primarily daughters without clitoris. PMID:19807967

  2. Bayes reconstruction of missing teeth

    DEFF Research Database (Denmark)

    Sporring, Jon; Jensen, Katrine Hommelhoff

    2008-01-01

     We propose a method for restoring the surface of tooth crowns in a 3D model of a human denture, so that the pose and anatomical features of the tooth will work well for chewing. This is achieved by including information about the position and anatomy of the other teeth in the mouth. Our system...... contains two major parts: A statistical model of a selection of tooth shapes and a reconstruction of missing data. We use a training set consisting of 3D scans of dental cast models obtained with a laser scanner, and we have build a model of the shape variability of the teeth, their neighbors...... regularization of the log-likelihood estimate based on differential geometrical properties of teeth surfaces, and we show general conditions under which this may be considered a Bayes prior.Finally we use Bayes method to propose the reconstruction of missing data, for e.g. finding the most probable shape...

  3. Endodontic management of taurodontic teeth

    Directory of Open Access Journals (Sweden)

    Prakash R

    2005-01-01

    Full Text Available Taurodontism is a morpho-anatomical change in the shape of the tooth in which the body of the tooth is enlarged and the roots are reduced in size. Although taurodontism is a dental rarity, this unusual radicular form should merit circumspect considerations in planning and treatment. Endodontic management in taurodont teeth has been described as complex and difficult. The present paper describes the successful completion of endodontic treatment in three taurodontic teeth with appropriate use of instruments and techniques and also emphasizes the need for post endodontic rehabilitation.

  4. Identification and Characterization of MicroRNAs in Macaca fascicularis by EST Analysis

    Directory of Open Access Journals (Sweden)

    Hao Yang

    2012-01-01

    Full Text Available MicroRNAs (miRNAs are small noncoding RNAs which repress gene expression at the posttranscriptional level. In this study, an expressed sequence tag (EST-based combined method was applied for the detection of miRNAs in Macaca fascicularis which is used as a model animal extensively in medical experiments, particularly those involved with neuroscience and disease. Initially, previously known miRNA sequences from metazoans were used to blast with the EST databases of Macaca fascicularis, and then a range of filtering criteria was conducted to remove some pseudo ones. At last a total of 8 novel conserved miRNAs were identified; their functions were further predicted and analyzed. Together, our study provides insight into miRNAs and their functions in Macaca fascicularis, indicating that the EST analysis is an efficient and affordable alternative approach for identifying novel miRNA candidates.

  5. High resolution karyotype of Thai crab-eating macaque (Macaca fascicularis

    Directory of Open Access Journals (Sweden)

    Fan Xiaobo

    2014-01-01

    Full Text Available Comparative chromosome banding analysis and/or fluorescence in situ hybridization (FISH studies are established approaches to compare human and ape chromosomes. FISH banding is a relatively new and not routinely applied method very well suited to provide to a better understanding of the evolutionary history of primate and human phylogeny. Here multicolor banding (MCB-applying probes derived from Homo sapiens were used to analyze the chromosomes of Thai crab-eating macaque (Macaca fascicularis. The results agree with those of previous studies in other macaques, e.g. Macaca sylvanus or Macaca nemestrina. This result highlights that morphological differences within the Cercopithecoidea must be found rather in subchromosomal changes or even in epigenetics than in gross structural alterations.

  6. High resolution karyotype of thai crab-eating macaque (Macaca fascicularis

    Directory of Open Access Journals (Sweden)

    Fan Xiaobo

    2014-01-01

    Full Text Available Comparative chromosome banding analysis and/or fluorescence in situ hybridization (FISH studies are established approaches to compare human and ape chromosomes. FISH-banding is a relatively new and not routinely applied method suited very well to provide to a better understanding of the evolutionary history of primate and human phylogeny. Here multicolor banding (MCB applying probes derived from Homo sapiens was used to analyze the chromosomes of Thai crab-eating macaque (Macaca fascicularis. The results agree with those of previous studies in other macaques, e.g. Macaca sylvanus or Macaca nemestrina. This result pinpoints, that morphological differences within the Ceropithecoidae must be founded rather in subchromosomal changes or even in epigenetics than in gross structural alterations.

  7. Grooming reciprocity in female tibetan macaques macaca thibetana.

    Science.gov (United States)

    Xia, Dongpo; Li, Jinhua; Garber, Paul A; Sun, Lixing; Zhu, Yong; Sun, Binghua

    2012-06-01

    Grooming among nonhuman primates is widespread and may represent an important service commodity that is exchanged within a biological marketplace. In this study, using focal animal sampling methods, we recorded grooming relationships among 12 adult females in a free-ranging group of Tibetan macaques (Macaca thibetana) at Huangshan, China, to determine the influence of rank and kinship on grooming relationships, and whether females act as reciprocal traders (exchange grooming received for grooming given) or interchange traders (interchange grooming for social tolerance or other commodities). The results showed that: (1) grooming given was positively correlated with grooming received; (2) kinship did not exert a significant influence on grooming reciprocity; and (3) grooming reciprocity occurred principally between individuals of adjacent rank; however, when females of different rank groomed, females tended to groom up the hierarchy (lower ranking individuals groomed higher ranking individuals more than vice versa). Our results support the contention that both grooming reciprocity and the interchange of grooming for tolerance represent important social tactics used by female Tibetan macaques.

  8. Evaluation of Infrared Thermometry in Cynomolgus Macaques (Macaca fascicularis)

    Science.gov (United States)

    Laffins, Michael M; Mellal, Nacera; Almlie, Cynthia L; Regalia, Douglas E

    2017-01-01

    Recording an accurate body temperature is important to assess an animal's health status. We compared temperature data from sedated cynomolgus macaques (Macaca fascicularis) to evaluate differences between rectal, infrared (inguinal and chest), and implanted telemetry techniques with the objective of demonstrating the diagnostic equivalence of the infrared device with other approaches. Infrared thermometer readings are instantaneous and require no contact with the animal. Body temperature data were obtained from 205 (137 male, 68 female) cynomolgus macaques under ketamine (10 mg/kg IM) sedation over a 3-mo period during scheduled physical examinations. Infrared measurements were taken 5 cm from the chest and inguinal areas. We evaluated 10 (9 functional devices) sedated cynomolgus macaques (5 male, 5 female) implanted with telemetry units in a muscular pouch between the internal and external abdominal oblique muscles. We determined that the mean body temperature acquired by using telemetry did not differ from either the mean of inguinal and chest infrared measurements but did differ from the mean of temperature obtained rectally. In addition, the mean rectal temperature differed from the mean of the inguinal reading but not the mean of the chest temperature. The results confirm our hypothesis that the infrared thermometer can be used to replace standard rectal thermometry. PMID:28905720

  9. Cynomolgus macaque (Macaca fascicularis) immunoglobulin heavy chain locus description.

    Science.gov (United States)

    Yu, Guo-Yun; Mate, Suzanne; Garcia, Karla; Ward, Michael D; Brueggemann, Ernst; Hall, Matthew; Kenny, Tara; Sanchez-Lockhart, Mariano; Lefranc, Marie-Paule; Palacios, Gustavo

    2016-07-01

    Cynomolgus macaques (Macaca fascicularis) have become an important animal model for biomedical research. In particular, it is the animal model of choice for the development of vaccine candidates associated with emerging dangerous pathogens. Despite their increasing importance as animal models, the cynomolgus macaque genome is not fully characterized, hindering molecular studies for this model. More importantly, the lack of knowledge about the immunoglobulin (IG) locus organization directly impacts the analysis of the humoral response in cynomolgus macaques. Recent advances in next generation sequencing (NGS) technologies to analyze IG repertoires open the opportunity to deeply characterize the humoral immune response. However, the IG locus organization for the animal is required to completely dissect IG repertoires. Here, we describe the localization and organization of the rearranging IG heavy (IGH) genes on chromosome 7 of the cynomolgus macaque draft genome. Our annotation comprises 108 functional genes which include 63 variable (IGHV), 38 diversity (IGHD), and 7 joining (IGHJ) genes. For validation, we provide RNA transcript data for most of the IGHV genes and all of the annotated IGHJ genes, as well as proteomic data to validate IGH constant genes. The description and annotation of the rearranging IGH genes for the cynomolgus macaques will significantly facilitate scientific research. This is particularly relevant to dissect the immune response during vaccination or infection with dangerous pathogens such as Ebola, Marburg and other emerging pathogens where non-human primate models play a significant role for countermeasure development.

  10. Risk factors for dystocia in pigtailed macaques (Macaca nemestrina).

    Science.gov (United States)

    Stockinger, Diane E; Torrence, Anne E; Hukkanen, Renee R; Vogel, Keith W; Hotchkiss, Charlotte E; Ha, James C

    2011-04-01

    Dystocia (difficult labor) is an important component of the management of nonhuman primates and results in significant fetal and maternal morbidity and increased use of veterinary resources. Dystocias can arise from abnormalities of the maternal pelvis or fetus or uncoordinated uterine activity. Although risk factors for stillbirths have been established in nonhuman primates, risk factors for dystocias have not. The objective of this study was to determine maternal and fetal risk factors for dystocia in macaques. Retrospective data were collected from 83 pigtailed macaques (Macaca nemestrina) diagnosed with dystocia. The diagnosis of dystocia was made based on clinical or pathologic evidence. Maternal records of age, reproductive history, experimental history, clinical records, and fetal birth weight and any applicable fetal necropsy reports were reviewed. The gestational age of the fetus, the infant's birth weight, total previous births by the dam, and the proportions of both viable delivery (inverse effect) and surgical pregnancy interventions (direct effect) in the dam's history generated a model that maximized the experimental variance for predicting dystocia in the current pregnancy and explained 24% of the dystocia deliveries. The number of total previous births and proportion of previous cesarean sections accounted for the greatest effect. This model can identify individual dams within a colony that are at risk for dystocias and allow for changes in breeding colony management, more intense monitoring of dams at risk, or allocation of additional resources.

  11. A Macaca mulatta model of fulminant hepatic failure

    Institute of Scientific and Technical Information of China (English)

    Ping Zhou; Hong Bu; Jie Xia; Gang Guo; Li Li; Yu-Jun Shi; Zi-Xing Huang; Qiang Lu; Hong-Xia Li

    2012-01-01

    AIM: To establish an appropriate primate model of fulminant hepatic failure (FHF). METHODS: We have, for the first time, established a large animal model of FHF in Macaca mulatta by intraperitoneal infusion of amatoxin and endotoxin. Clinical features, biochemical indexes, histopathology and iconography were examined to dynamically investigate the progress and outcome of the animal model. RESULTS: Our results showed that the enzymes and serum bilirubin were markedly increased and the enzyme-bilirubin segregation emerged 36 h after toxin administration. Coagulation activity was significantly decreased. Gradually deteriorated parenchymal abnormality was detected by magnetic resonance imaging (MRI) and ultrasonography at 48 h. The liver biopsy showed marked hepatocyte steatosis and massive parenchymal necrosis at 36 h and 49 h, respectively. The autopsy showed typical yellow atrophy of the liver. Hepatic encephalopathy of the models was also confirmed by hepatic coma, MRI and pathological changes of cerebral edema. The lethal effects of the extrahepatic organ dysfunction were ruled out by their biochemical indices, imaging and histopathology. CONCLUSION: We have established an appropriate large primate model of FHF, which is closely similar to clinic cases, and can be used for investigation of the mechanism of FHF and for evaluation of potential medical therapies.

  12. Rhesus monkeys (Macaca mulatta) map number onto space.

    Science.gov (United States)

    Drucker, Caroline B; Brannon, Elizabeth M

    2014-07-01

    Humans map number onto space. However, the origins of this association, and particularly the degree to which it depends upon cultural experience, are not fully understood. Here we provide the first demonstration of a number-space mapping in a non-human primate. We trained four adult male rhesus macaques (Macaca mulatta) to select the fourth position from the bottom of a five-element vertical array. Monkeys maintained a preference to choose the fourth position through changes in the appearance, location, and spacing of the vertical array. We next asked whether monkeys show a spatially-oriented number mapping by testing their responses to the same five-element stimulus array rotated ninety degrees into a horizontal line. In these horizontal probe trials, monkeys preferentially selected the fourth position from the left, but not the fourth position from the right. Our results indicate that rhesus macaques map number onto space, suggesting that the association between number and space in human cognition is not purely a result of cultural experience and instead has deep evolutionary roots.

  13. Molecular mapping of striatal subdivisions in juvenile Macaca Mulata

    Science.gov (United States)

    O’Connor, Joann; Muly, Emil C.; Hemby, Scott E.

    2016-01-01

    The striatum of the primate brain can be subdivided into three distinct anatomical subregions: caudate (CAU), putamen (PUT), and ventral striatum (VS). Although these subregions share several anatomical connections, cell morphological, and histochemical features, they differ considerably in their vulnerability to different neurological and psychiatric diseases, and these brain regions have significantly different functions in health and disease. In order to better understand the molecular underpinnings of the different disease and functional vulnerabilities, transcriptional profiles were generated from the CAU, PUT, and VS of five juvenile rhesus macaques (Macaca mulatta) using human cDNA neuromicroarrays containing triplicate spots of 1227 cDNAs. Differences in microarray gene expression were assessed using z score analysis and 1.5-fold change between paired subregions. Clustering of genes based on dissimilarity of expression patterns between regions revealed subregion specific expression profiles encoding G-protein-coupled receptor signaling transcripts, transcription factors, kinases and phosphatases, and cell signaling and signal transduction transcripts. Twelve transcripts were examined using quantitative real-time PCR (qPCR), and 81% demonstrated alterations similar to those seen with microarray analysis, some of which were statistically significant. Subregion specific transcription profiles support the anatomical differentiation and potential disease vulnerabilities of the respective subregions. PMID:16455077

  14. "Early baby teeth": Folklore and facts.

    Science.gov (United States)

    Maheswari, N Uma; Kumar, B P; Karunakaran; Kumaran, S Thanga

    2012-08-01

    Variations in the newborns' oral cavity have been an enduring interest to the pediatric dentist. The occurrence of natal and neonatal teeth is a rare anomaly, which for centuries has been associated with diverse superstitions among many different ethnic groups. Natal teeth are more frequent than neonatal teeth, the ratio being approximately 3:1. The purpose of this case report is to review the literature related to the natal teeth folklore and misconceptions and discuss their possible etiology and treatment.

  15. Bayes reconstruction of missing teeth

    DEFF Research Database (Denmark)

    Sporring, Jon; Jensen, Katrine Hommelhoff

    2008-01-01

     We propose a method for restoring the surface of tooth crowns in a 3D model of a human denture, so that the pose and anatomical features of the tooth will work well for chewing. This is achieved by including information about the position and anatomy of the other teeth in the mouth. Our system...... of a missing tooth based on the best match with our shape model on the known data, and we superior improved reconstructions of our full system....

  16. Delayed replantation of avulsed teeth

    Directory of Open Access Journals (Sweden)

    Adil N

    2007-05-01

    Full Text Available Dental injuries are very common and their extent has been classified by Ellis. Avulsion of tooth is a grievous injury and ranges from 1-16% among the traumatic injuries, of which maxillary anterior are commonest. Reimplantation of avulsed teeth is a standard procedure. However, it has certain limitations. Most often their management is very challenging. In this case report we are presenting the management of maxillary incisors by replantation after 36 hrs in a 12 year old girl.

  17. Emotional states after grooming interactions in Japanese macaques (Macaca fuscata).

    Science.gov (United States)

    Ueno, Masataka; Yamada, Kazunori; Nakamichi, Masayuki

    2015-11-01

    In animal societies, the effect of grooming interactions on anxiety reduction is unclear. This study examined the effects of giving and receiving grooming on anxiety reduction in free ranging female Japanese macaques (Macaca fuscata) by measuring rates of self-scratching as an index of anxiety. In this study, the authors used a focal-animal sampling method, targeting 17 females at Katsuyama, Okayama prefecture, Japan. They evaluated affiliative relationships, which were defined by standard proximity rates, and found that females' self-scratching rates were lower after grooming affiliated partners than during matched-control periods (occurring on another day, beginning at approximately the same time of day as the corresponding postgrooming period) and not after grooming unaffiliated partners. Moreover, regardless of affiliative relationships, self-scratching rates were lower after receiving grooming than during matched-control periods. These findings did not change after excluding data in which groomer and groomee were in proximity after the grooming interaction. In addition, multivariable analysis showed that affiliative relationships, but not kinship or rank distances, were related to differences in the rates of self-scratching between giving grooming and matched-control periods. In contrast, neither affiliative relationships nor kinship nor rank distances affected differences in self-scratching rates between receiving grooming and matched-control periods. Therefore, individuals' anxiety levels decreased both after giving grooming to affiliated partners and after receiving grooming, regardless of affiliative relationships. This is the first empirical study to support the notion that giving grooming to affiliated partners is self-rewarding in Japanese macaques.

  18. Seed dispersal by rhesus macaques Macaca mulatta in Northern India.

    Science.gov (United States)

    Sengupta, Asmita; McConkey, Kim R; Radhakrishna, Sindhu

    2014-12-01

    Frugivorous primates are important seed dispersers and their absence from forest patches is predicted to be detrimental to tropical forest regeneration and recruitment. With the reduction of primate populations globally, ecologically resilient primate species, characterized by dietary flexibility and the ability to thrive in a variety of habitats, assume new importance as seed dispersers. The most widely distributed non-human primate, the rhesus macaque Macaca mulatta has been intensively studied but little is known about its role in maintaining ecosystem structure and functions. Due to their frugivorous diet, large group sizes, large home ranges and tolerance to disturbance, rhesus macaques may be effective seed dispersers. We studied seed dispersal by rhesus macaques at the Buxa Tiger Reserve, India, through a combination of behavioural observations and germination experiments. Rhesus macaques dispersed 84% of the 49 species they fed on either through spitting or defecation. Nearly 96% of the handled seeds were undamaged and 61% of the species for which germination tests were performed had enhanced germination. Almost 50% of the monitored seeds among those deposited in situ germinated and 22% established seedlings, suggesting that rhesus macaques are important seed dispersers in tropical forests. Due to their widespread distribution and large populations, rhesus macaques are perceived as common and are categorized as Least Concern on the IUCN Red List, effectively excluding them from any conservation plans. Based on the results of our study, we argue that rhesus macaques fulfill critical ecological functions in their habitat and that this parameter must be taken into consideration when they are reviewed for conservation priorities.

  19. Temporomandibular joint forces measured at the condyle of Macaca arctoides.

    Science.gov (United States)

    Boyd, R L; Gibbs, C H; Mahan, P E; Richmond, A F; Laskin, J L

    1990-06-01

    Forces were measured at the articular surface of the temporomandibular joint (TMJ) condyle in two stump-tail monkeys (Macaca arctoides) during chewing, incisal biting, and drinking and also during aggressive behaviors. Force was measured with a thin piezoelectric foil transducer, which was cemented over the anterior and superior surfaces of the condyle. Wires from the upper and lower surfaces of the foil were insulated between two layers of Teflon tape and run subcutaneously to a telemetry unit, which was implanted in the upper back. Force applied across the foil by the condyle was detected by the telemetry unit and transmitted to an FM radio receiver outside the animal. The FM signals were received and demodulated, and a signal proportional to the force applied between the condyle and the TMJ fossa was displayed on a chart recorder. Data were collected over an 8-day period. The animals were not constrained. The TMJ was found to be load bearing. The greatest force of 39.0 lb (17.7 kg) was measured during feisty vocal aggression. Forces ranged as high as 34.5 lb (15.7 kg) during chewing and 28.5 lb (13.0 kg) during incisal biting. Forces were greater on the working (food) side than on the nonworking (balancing) side by average ratios of 1.4 to 2.6. A large unilateral interference at the most distal molar greatly disturbed chewing. It reduced TMJ forces by 50% or more, and the monkey refused to chew on the side opposite the interference.

  20. Iron deposition in modern and archaeological teeth

    Energy Technology Data Exchange (ETDEWEB)

    Williams, A.-M.M., E-mail: AnneMarie.Williams@utas.edu.au [School of Medicine, Private Bag 34, University of Tasmania, Hobart 7001 (Australia); Siegele, R. [Australian Nuclear Science and Technology Organisation, PMB 1, Menai, NSW 2234 (Australia)

    2014-09-15

    Iron surface concentrations and profile maps were measured on the enamel of archaeological and modern teeth to determine how iron is deposited in tooth enamel and if it was affected by the post-mortem environment. Teeth from Australian children who died in the second half of the 19th century were compared with contemporary teeth extracted for orthodontic purposes. Surface analysis of the teeth was performed using the 3 MV Van Der Graff Accelerator at The Australian Nuclear Science and Technology Organisation (ANSTO), Sydney, Australia. A small sample of teeth were then cut in the mid sagittal plane and analysed using ANSTO High Energy Heavy Ion Microprobe. Maps and linear profiles were produced showing the distribution of iron across the enamel. Results show that both the levels and distribution of iron in archaeological teeth is quite different to contemporary teeth, raising the suggestion that iron has been significantly altered by the post-mortem environment.

  1. Iron deposition in modern and archaeological teeth

    Science.gov (United States)

    Williams, A.-M. M.; Siegele, R.

    2014-09-01

    Iron surface concentrations and profile maps were measured on the enamel of archaeological and modern teeth to determine how iron is deposited in tooth enamel and if it was affected by the post-mortem environment. Teeth from Australian children who died in the second half of the 19th century were compared with contemporary teeth extracted for orthodontic purposes. Surface analysis of the teeth was performed using the 3 MV Van Der Graff Accelerator at The Australian Nuclear Science and Technology Organisation (ANSTO), Sydney, Australia. A small sample of teeth were then cut in the mid sagittal plane and analysed using ANSTO High Energy Heavy Ion Microprobe. Maps and linear profiles were produced showing the distribution of iron across the enamel. Results show that both the levels and distribution of iron in archaeological teeth is quite different to contemporary teeth, raising the suggestion that iron has been significantly altered by the post-mortem environment.

  2. Acute-phase responses in healthy and diseased rhesus macaques (Macaca mulatta)

    DEFF Research Database (Denmark)

    Krogh, Anne Kirstine Havnsøe; Lundsgaard, Jo F. H.; Bakker, Jaco

    2014-01-01

    Five acute-phase reactants—serum amyloid A (SAA), C-reactive protein (CRP), haptoglobin, albumin, and iron—were measured using commercially available assays in 110 healthy rhesus macaques (Macaca mulatta), and reference intervals were established for future use in health monitoring of this specie...

  3. Essentialism in the Absence of Language? Evidence from Rhesus Monkeys ("Macaca mulatta")

    Science.gov (United States)

    Phillips, Webb; Shankar, Maya; Santos, Laurie R.

    2010-01-01

    We explored whether rhesus monkeys (Macaca mulatta) share one important feature of human essentialist reasoning: the capacity to track category membership across radical featural transformations. Specifically, we examined whether monkeys--like children (Keil, 1989)--expect a transformed object to have the internal properties of its original…

  4. Positioning of anterior teeth in removable dentures

    Directory of Open Access Journals (Sweden)

    Strajnić Ljiljana

    2002-01-01

    Full Text Available Introduction The aim of this paper was to present methods of placement of artificial anterior teeth in edentulous individuals. The following review takes account of the majority of papers published during the last 100 years. The review has been divided into sections regarding the method used to determine the position of artificial anterior teeth. Geometric aspect Gysi (1895-1920 produced the first scientific theory about the position of artificial anterior teeth. Physiognomic theory The aim of this theory is to find the most natural position for artificial anterior teeth for each individual. Camper's "face angle" as a physiognomic criterion, has been introduced in papers of Wehrli (1961, Marxhors (1966, Tanzer (1968, Lombardi (1973. Esthetic aspect Important names in the field of dental esthetics are: Schön and Singer (1961, Arnheim (1965, Krajiček (1969, Tanzer (1968, Lombardi (1973, Goldstein (1976. They have introduced principles of visual aspects for selection of contours, dimension and position of artificial anterior teeth. Constitution aspect Flagg (1880, Williams (1913 and Hrauf (1957, 1958, have considered body constitution and individual characteristics regarding position of artificial anterior teeth. Physiological theory In 1971, Marxhors pointed to the fact that the position of artificial teeth corresponds with the function of the surrounding soft tissue and from the aspect of physiognomy as well. Phonetic aspect According to Silverman (1962 artificial anterior teeth are nearest when we pronounce the sound "S". Cephalometrical research Rayson (1970, Watson (1989, Strajnić Lj. (1999, Bassi F. (2001 have presented cephalometric radiographic analyses of natural anterior teeth compared with cephalometric radiographic analyses of artificial anterior teeth. A review of dental literature shows several factors suggesting modalities which should determine the position of artificial anterior teeth. Numerous methods have been designed for

  5. Supernumerary teeth "mesiodens". Case report.

    Science.gov (United States)

    Itro, A; Difalco, P

    2003-09-01

    The supernumerary tooth is an anomaly of dental eruption that is not rare to find in the clinical practice. Among the supernumerary teeth the "mesiodens" is most frequent. The mesiodens is found in the region of the superior central incisors and it can be the cause of many complications. The aim of this work is the description of a rare symptomatic case of mesiodens and the diagnostic and therapeutic strategies to adopt when this dental anomaly occurs. In particular the authors suggest making radiographic examinations only in the family of patients with dental anomalies of number, thinking that the incidence of such anomalies is too low to justify mass radiographic examinations.

  6. [Esthetic restorations of primary anterior teeth].

    Science.gov (United States)

    Elqadir, A Jamil; Shapira, J; Ziskind, K; Ram, D

    2013-04-01

    Esthetic treatment of primary teeth is one of the greatest challenges to pediatric dentists. A variety of restorative options using full coverage are available for anterior primary teeth. In the last half century the emphasis on treatment of severely decayed primary teeth shifted from extraction to restoration. In the past, restorations consisted of placement of stainless steel crowns on severely decayed teeth. However, they are esthetically unacceptable today. Over the last decade parents expect a higher esthetic standard for their children's primary teeth. Thus, the restoration should provide esthetic appearance and durability in addition to restoring function. The purpose of this review is to describe the types of full coverage options for anterior primary teeth currently available.

  7. Supernumerary teeth in non-syndromic patients

    Energy Technology Data Exchange (ETDEWEB)

    Mali, Santosh; Karjodkar, Freny Rashmiraj; Sontakke, Subodh; Sansare, Kaustubh [Nair Hospital Dental College, Maharashtra (India)

    2012-03-15

    Hyperdontia or supernumerary teeth without associated syndrome is a rare phenomenon, as supernumerary teeth are usually associated with cleft lip and palate or other syndromes such as Gardner's syndrome, cleidocranial dysplasia, and so on. Five patients with supernumerary teeth visited our department. They had no familial history or other pathology, certain treatment protocols was modified due to the presence of supernumerary teeth. Non-syndromic supernumerary teeth, if asymptomatic, need to have periodical radiographic observation. If they showed no variation as they impacted in the jaw, careful examination is necessary because they may develop into pathological status such as dentigerous cysts. The importance of a precise clinical history and radiographic examination for patients with multiple supernumerary teeth should be emphasized.

  8. Orthodontic movement of endodontically treated teeth

    Directory of Open Access Journals (Sweden)

    Alberto Consolaro

    2013-08-01

    Full Text Available Often there is the need of moving teeth endodontically treated or teeth still in endodontic treatment. In order to collaborate with the comprehension and substantiation of the following subjects will be discussed: 1 Orthodontic movement in endodontically treated teeth without periapical lesion, 2 Orthodontic movement in endodontically treated teeth with inflammatory periapical lesion, and 3 Orthodontic movement in teeth endodontically treated due to aseptic pulp necrosis by dental trauma. In practically all situations, endodontically treated teeth to be orthodontically moved must be subjected to a careful evaluation by the endodontist about the conditions, adequate or not, of the endodontic treatment. Then, in this paper it was sought to induce an insight for new clinical researches about the theme that may definitely prove the information obtained by interrelations of information in parallel to clinical practice.

  9. Regional odontodysplasia (Ghost teeth). A case report.

    OpenAIRE

    Kannan S; Saraswathi K

    2001-01-01

    Regional odontodysplasia is a rare development anomaly affecting the teeth with an unknown etiology. This dental abnormality involves the hard tissues of the teeth that are derived from both epithelial (enamel) and mesenchymal (dentine & cementum) components of the tooth forming apparatus. Teeth in a region or quadrant of maxilla or mandible are affected to the extent that they exhibit short roots, wide open apical foramen and large pulp chamber, the thinness and poor mineralisation quali...

  10. Surrogate Mobility and Orientation Affect the Early Neurobehavioral Development of Infant Rhesus Macaques (Macaca mulatta)

    OpenAIRE

    Amanda M Dettmer; Ruggerio, Angela M.; Novak, Melinda A.; Meyer, Jerrold S.; Suomi, Stephen J.

    2008-01-01

    A biological mother’s movement appears necessary for optimal development in infant monkeys. However, nursery-reared monkeys are typically provided with inanimate surrogate mothers that move very little. The purpose of this study was to evaluate the effects of a novel, highly mobile surrogate mother on motor development, exploration, and reactions to novelty. Six infant rhesus macaques (Macaca mulatta) were reared on mobile hanging surrogates (MS) and compared to six infants reared on standard...

  11. STEREOLOGICAL ANALYSIS OF THE COCHLEAR NUCLEI OF MONKEY (MACACA FASCICULARIS AFTER DEAFFERENTATION

    Directory of Open Access Journals (Sweden)

    Ana M Insausti

    2011-05-01

    Full Text Available The cochlear nuclei (CN in the brainstem receive the input signals from the inner ear through the cochlear nerve, and transmit these signals to higher auditory centres. A variety of lesions of the cochlear nerve cause deafness. As reported in the literature, artificial removal of auditive input, or 'deafferentation', induces structural alterations in the CN. The purpose of this study was to estimate a number of relevant stereological parameters of the CN in control and deafferented Macaca fascicularis monkeys.

  12. Construction and Validation of a Systematic Ethogram of Macaca fascicularis in a Free Enclosure

    OpenAIRE

    Fan Xu; Liang Xie; Xin Li; Qi Li; Tao Wang; Yongjia Ji; Fei Kong; Qunlin Zhan; Ke Cheng; Liang Fang; Peng Xie

    2012-01-01

    Behavioral studies in non-human primates have become ideal models for further investigations into advanced cognitive function in humans. To date, there is no systematic ethogram of the cynomolgus monkey (Macaca fascicularis) in a free enclosure. In a field observation of 6012 subjects, 107 distinct behaviors of M. fascicularis were preliminarily described. 83 of these behaviors were then independently validated through a randomized cohort and classified into 12 behavioral categories. 53 of th...

  13. Positive reinforcement training as enrichment for singly housed rhesus macaques (Macaca mulatta)

    OpenAIRE

    Baker, KC; Bloomsmith, MA; Neu, K; Griffis, C; Maloney, M.

    2010-01-01

    Positive reinforcement training is one component of behavioural management employed to improve psychological well-being. There has been regulatory promotion to compensate for restricted social housing in part by providing human interaction to singly caged primates, implying an efficacy standard for evaluating human interaction. The effect of positive reinforcement training on the behaviour of 61 singly housed laboratory rhesus macaques (Macaca mulatta) was evaluated at two large primate facil...

  14. Concrescent triplets involving primary anterior teeth

    Directory of Open Access Journals (Sweden)

    Urvashi Sharma

    2013-01-01

    Full Text Available Odontogenesis is a complex process wherein more than 200 genes are known to play a significant role in tooth development. An imbalance can lead to an abnormality in the number, size, shape or structure of the developing tooth/teeth. The presence of an extra dental lamina forms a supernumerary tooth. The supernumerary teeth are of two types: A rudimentary tooth where the supernumerary tooth does not resemble any tooth in the normal series or a supplemental tooth in which this anomalous tooth resembles one in the normal series. It is also very rare to encounter triple teeth in primary dentition. The union of these teeth may be through fusion, gemination, concrescence or a combination of fusion and gemination. Presented is a rare case of concrescence involving maxillary deciduous incisors and a supplemental tooth in a 7-year-old boy. The differential diagnosis, etiology, and complications of primary anterior triple teeth are discussed.

  15. White-cheeked macaque (Macaca leucogenys): A new macaque species from Medog, southeastern Tibet.

    Science.gov (United States)

    Li, Cheng; Zhao, Chao; Fan, Peng-Fei

    2015-07-01

    We describe a newly discovered Macaca species from the Medog, in southeastern Tibet, China, Macaca leucogenys sp. nov or the "white-cheeked macaque". Based on 738 photos taken during direct observations and captured by camera traps this new species appears to be distinct from the Macaca sinica species group. Moreover, the species is distinguished from all potential sympatric macaque species (M. mulatta, M. thibetana, M. assamensis, and M. munzala) in exhibiting a suite of pelage characteristics including relatively uniform dorsal hair pattern, hairy ventral pelage, relative hairless short tail, prominent pale to white side- and chin-whiskers creating a white cheek and round facial appearance, dark facial skin on the muzzle, long and thick hairs on its neck, and a round rather than arrow-shaped male genitalia. This new macaque species was found to exploit a diverse set of habitat types from tropical forest at 1395 m, to primary and secondary evergreen broad-leaved forest at 2000 m, as well as mixed broadleaf-conifer forest at 2700 m. Its range may extend to neighboring counties in Tibet and the part of southeastern Tibet controlled by India. The white-cheeked macaque is threatened by illegal hunting and the construction of hydropower stations. Discovery of this new primate species further highlights the high value for biodiversity conservation of southeastern Tibet and calls for more intensive surveys, studies, and environmental protection in this area.

  16. Caries detection in primary teeth is less challenging than in permanent teeth

    Directory of Open Access Journals (Sweden)

    Fausto M Mendes

    2013-01-01

    Full Text Available Introduction: Most studies about caries detection methods have been performed using permanent teeth. Primary teeth, however, present significant differences from permanent teeth; hence findings of these studies with permanent teeth cannot be extrapolated. The Hypothesis: Our hypothesis is that the caries diagnosis process in primary teeth is less challenging than in permanent teeth. This assertion is based on the fact that primary enamel is thinner and the caries process progresses faster in this type of teeth when compared to permanent teeth. For these reasons, the majority of caries lesions in primary teeth would be more evident and therefore, easily detected through visual inspection. Only a few number of caries lesions would be missed by visual inspection. Thus, adjunct diagnostic methods, such as radiographs, would be unnecessary for primary teeth. Evaluation of the Hypothesis: To evaluate this hypothesis, researchers should conduct studies about the performance of the caries detection methods avoiding selection bias and defining appropriate settings. Clinical trials randomizing the diagnostic strategies would be worthwhile. The evidence supporting the benefits of adjunct methods in detecting caries lesions in primary lesions is limited. However, clinical guidelines have recommended the use of the radiographic method to detect caries in primary teeth in all symptomless children. The confirmation of our hypothesis would lead to the need to re-evaluate such guidelines.

  17. HYPODONTIA OF PERMANENT TEETH IN A KENYAN POPULATION

    African Journals Online (AJOL)

    Of the children with hypodontia, about 80 % lacked one or two teeth, 54 % had ... of patients prior to removal of permanent teeth for orthodontic reasons. INTRODUCTION .... (iv) extraction of the primary teeth followed by immediate orthodontic ...

  18. Bruxism (Teeth Grinding or Clenching) (For Parents)

    Science.gov (United States)

    ... Old Feeding Your 1- to 2-Year-Old Bruxism (Teeth Grinding or Clenching) KidsHealth > For Parents > Bruxism ( ... called bruxism , which is common in kids. About Bruxism Bruxism is the medical term for the grinding ...

  19. Mothers Perception of Teething in Children

    African Journals Online (AJOL)

    TNHJOURNALPH

    manage them. ... commonest problems reported were fever ... serious health implications for management of ... babies may refuse to eat due to the pain. 4 The pain associated with teething is ... Also, the level of pain each baby can handle.

  20. Take Care of Your Teeth and Gums

    Science.gov (United States)

    ... drink alcohol, drink only in moderation. What causes tooth decay and gum disease? Plaque (“plak”) is a sticky ... your teeth too long, it can lead to tooth decay and gum disease. Brushing and flossing help get ...

  1. Supernumerary teeth: Report of four unusual cases

    Directory of Open Access Journals (Sweden)

    Arun Kumar

    2012-01-01

    Full Text Available Supernumerary tooth denotes duplication of tooth in the normal series. It is a developmental anomaly and has been argued to arise from multiple etiologies. These teeth may remain embedded in the alveolar bone or can erupt into the oral cavity. The supernumerary tooth might cause esthetic and/or functional problems, especially if it is situated in the maxillary anterior region. Complications reported were delayed or prevented eruption of succedaneous teeth, displacement or rotation, crowding of the affected region, abnormal diastema, dilacerations, cystic formation, and sometime eruption into the nasal cavity. In this case report, four unusual cases of supernumerary teeth that resulted in varying degrees of disturbances in permanent dentition are presented. Conservative surgical intervention and light orthodontic forces were used to bring the teeth into normal position with minimal disturbance to the surrounding oral structures.

  2. Surgical and orthodontic management of impacted teeth.

    Science.gov (United States)

    Kokich, V G; Mathews, D P

    1993-04-01

    This article has accomplished four objectives. First of all, the most commonly impacted teeth have been identified. Aside from the third molars, these teeth include the maxillary canines, maxillary central incisors, mandibular second premolars, and mandibular second molars. Second, the cause of impaction has been discussed. In most situations, these unerupted teeth have been diverted or are angulated aberrantly during development. Once the root apex has closed, they lose their potential to erupt. Third, the various surgical procedures to uncover these impacted teeth have been described. Three different techniques (excision, apically positioned flap, and closed eruption technique) may be used to uncover the impacted tooth. The specific criteria used to select the proper surgical technique were stated. Last, the orthodontic mechanics and integration of tooth movement and surgical procedures were delineated and illustrated for each of the various types of impactions and uncovering techniques.

  3. Supernumerary teeth: Report of four unusual cases.

    Science.gov (United States)

    Kumar, Arun; Namdev, Ritu; Bakshi, Lokesh; Dutta, Samir

    2012-04-01

    Supernumerary tooth denotes duplication of tooth in the normal series. It is a developmental anomaly and has been argued to arise from multiple etiologies. These teeth may remain embedded in the alveolar bone or can erupt into the oral cavity. The supernumerary tooth might cause esthetic and/or functional problems, especially if it is situated in the maxillary anterior region. Complications reported were delayed or prevented eruption of succedaneous teeth, displacement or rotation, crowding of the affected region, abnormal diastema, dilacerations, cystic formation, and sometime eruption into the nasal cavity. In this case report, four unusual cases of supernumerary teeth that resulted in varying degrees of disturbances in permanent dentition are presented. Conservative surgical intervention and light orthodontic forces were used to bring the teeth into normal position with minimal disturbance to the surrounding oral structures.

  4. Non-syndromic supernumerary teeth: report of a case with 6 supernumerary teeth

    Directory of Open Access Journals (Sweden)

    Taghibakhsh M

    2011-02-01

    Full Text Available "nBackground and Aims: Multiple supernumerary teeth are rare and often found in association with syndromes such as Gardner, Cleidocranial dysplasia and cleft lip and palate, with a much less chance for isolated"nnon-syndromic cases. The aim of this study was to report a case with 6 supernumerary teeth without syndromic association."nCase Report: The patient was a 33 year-old female, referred to oral diseases and diagnosis department with chief complaint of sensitivity to cold and hot food in right upper premolar region. Oral examination revealed 5 erupted lingually supernumerary teeth (four in mandibular and one in maxillary premolar region, respectively. Further panoramic radiography clarified an extra impacted tooth in the palatal region of left premolar maxillary area. All extra teeth had been appeared since the age of 17 during one year, as the patient claimed. Medical history and thorough clinical and paraclinical examinations were not significant except for the hypothyroidism, since 5 years ago. No other family member noticed to be the case. Based on our findings, a diagnosis of non-syndromic multiple supernumerary teeth was established."nConclusion: A thorough examination of each patient presented with supernumerary teeth, including panoramic and intraoral radiographic images may provide valuable information regarding accompanying syndromes and unerupted teeth. Early diagnosis is an essential step for orthodontic or surgical decisions making, preventing or avoiding worsening complications such as malocclusion, adjacent normal teeth delayed eruption or rotation, diasthema, cystic lesions and resorption of contiguous teeth.

  5. Supernumerary and supplemental teeth: case report.

    Science.gov (United States)

    Lo Giudice, G; Nigrone, V; Longo, A; Cicciù, M

    2008-06-01

    This is to report the case of a ten year old child affected by a numeric dental anomaly showing the pathologic condition characterised by the simultaneous presence of supernumerary and supplemental teeth. The anomaly was analysed to plan the best surgical and orthodontic treatments. Dental history, clinical and instrumental examinations were made to perform a correct orthodontic examination and diagnosis. A young patient was affected by numeric dental anomaly in the upper jaw. We observed a high number of teeth, specifically two normally formed supplemental lateral permanent incisors and an unerupted mesiodens placed between the upper central incisors. Firstly, the supplemental lateral teeth were extracted. This surgical therapy and the application of a space maintainer were made to permit the eruption of the permanent canines. Then the mesiodens also underwent surgical treatment (i.e. extraction). Eventually, physiologic eruption of permanent teeth was allowed by the planned surgical-orthodontic treatment. Aim of the surgical-orthodontic treatment was extraction of the unerupted supernumerary teeth to obtain the physiologic eruption of the permanent ones. Orthodontic treatment is important to solve malocclusions and maintaining the space for the eruption of permanent teeth. Aesthetics and function are two important parameters in modern dentistry. All clinicians should try to make a correct and rational diagnosis for both simple and complex dental pathologies. Particularly in young children, invasive and surgical disinclusive techniques can be substituted by interceptive orthodontic treatments.

  6. Straight, white teeth as a social prerogative.

    Science.gov (United States)

    Khalid, Abeer; Quiñonez, Carlos

    2015-06-01

    A distinguishing feature of North American society is preoccupation with self-image, as seen in the ritualistic nature of bodily practices aimed at constantly improving the body. Nowhere is this more apparent than in the prevailing fixation with straight, white teeth. While there is an ever-expanding literature on the sociology of body, very little has been written on teeth in this context. Using literature from anthropology, biology, dentistry, sociology and social psychology, this study attempts to answer: (1) Why have straight, white teeth become a beauty ideal in North American society? (2) What is the basis for this ideal? (3) How is this ideal propagated? It demonstrates that dental aesthetic tendencies are biologically, culturally and socially patterned. Concepts from the works of Pierre Bourdieu and Michel Foucault are used to illustrate how straight, white teeth contribute towards reinforcing class differences and how society exercises a disciplinary power on individuals through this ideal. It is concluded that modified teeth are linked to self and identity that are rooted in social structure. Moreover, teeth demonstrate the ways in which class differences are embodied and projected as symbols of social advantage or disadvantage. Implications on professional, public health, sociological and political levels are considered.

  7. What are the longevities of teeth and oral implants?

    DEFF Research Database (Denmark)

    Holm-Pedersen, Poul; Lang, Niklaus P; Müller, Frauke

    2007-01-01

    To analyse tooth loss and to evaluate the longevity of healthy teeth and teeth compromised by diseases and influenced by therapy as well as that of oral implants.......To analyse tooth loss and to evaluate the longevity of healthy teeth and teeth compromised by diseases and influenced by therapy as well as that of oral implants....

  8. Phylogeography of Barbary macaques (Macaca sylvanus) and the origin of the Gibraltar colony.

    Science.gov (United States)

    Modolo, Lara; Salzburger, Walter; Martin, Robert D

    2005-05-17

    The Barbary macaque (Macaca sylvanus) is the earliest offshoot of the genus Macaca and the only extant African representative, all other species being Asiatic. Once distributed throughout North Africa, M. sylvanus is now restricted to isolated forest fragments in Algeria and Morocco. The species is threatened; the maximum total wild population size is estimated at 10,000 individuals. Relationships among surviving wild subpopulations in Algeria (96 samples) and Morocco (116 samples) were examined by using 468-bp sequences from hypervariable region I of the mitochondrial DNA control region. Twenty-four different haplotypes were identified, differing by 1-26 mutational steps (0.2-5.6%) and 1 insertion. With one exception (attributable to secondary introduction in coastal Morocco), Algerian and Moroccan haplotypes are clearly distinct. However, whereas Moroccan subpopulations show little divergence in hypervariable region I sequences and little correspondence with geographical distribution, there is a deep division between two main subpopulations in Algeria and one marked secondary division, with haplotypes generally matching geographical distribution. Accepting an origin of the genus Macaca of 5.5 million years ago, the Moroccan population and the two main Algerian subpopulations diverged approximately 1.6 million years ago. Distinction between Moroccan and Algerian haplotypes permitted analysis of the origin of the Gibraltar colony of Barbary macaques (68 samples; 30% of the population). It is generally held that the present Gibraltar population descended from a dozen individuals imported during World War II. However, the Gibraltar sample was found to include Algerian and Moroccan haplotypes separated by at least 16 mutational steps, revealing a dual origin of the founding females.

  9. Construction and validation of a systematic ethogram of Macaca fascicularis in a free enclosure.

    Science.gov (United States)

    Xu, Fan; Xie, Liang; Li, Xin; Li, Qi; Wang, Tao; Ji, Yongjia; Kong, Fei; Zhan, Qunlin; Cheng, Ke; Fang, Liang; Xie, Peng

    2012-01-01

    Behavioral studies in non-human primates have become ideal models for further investigations into advanced cognitive function in humans. To date, there is no systematic ethogram of the cynomolgus monkey (Macaca fascicularis) in a free enclosure. In a field observation of 6012 subjects, 107 distinct behaviors of M. fascicularis were preliminarily described. 83 of these behaviors were then independently validated through a randomized cohort and classified into 12 behavioral categories. 53 of these behaviors were then selected to accurately reflect the daily mundane activity of the species in a free enclosure. These findings systematically document the behavior of M. fascicularis in a free enclosure for use in further investigations.

  10. Construction and validation of a systematic ethogram of Macaca fascicularis in a free enclosure.

    Directory of Open Access Journals (Sweden)

    Fan Xu

    Full Text Available Behavioral studies in non-human primates have become ideal models for further investigations into advanced cognitive function in humans. To date, there is no systematic ethogram of the cynomolgus monkey (Macaca fascicularis in a free enclosure. In a field observation of 6012 subjects, 107 distinct behaviors of M. fascicularis were preliminarily described. 83 of these behaviors were then independently validated through a randomized cohort and classified into 12 behavioral categories. 53 of these behaviors were then selected to accurately reflect the daily mundane activity of the species in a free enclosure. These findings systematically document the behavior of M. fascicularis in a free enclosure for use in further investigations.

  11. Are teeth evidence in acid environment

    Directory of Open Access Journals (Sweden)

    Makesh Raj

    2013-01-01

    Full Text Available Aim: Teeth are the most durable structures that resist destruction more than skeletal tissue Commercially available acids can be used to destroy the body or a part, to mask human identification. The present study examines the effect of caustic acids on human dentition. Materials and Methods: Ten upper anterior teeth each were immersed in 37% hydrochloric acid (conc. HCl, 65% nitric acid (conc. HNO 3 and 96% sulfuric acid (conc. H 2 SO 4 . Teeth were retrieved, washed in distilled water, dried, photographed and radiographed at intervals of 15 min, 30 min, 1 hr, 3 hr, 5 hr and 8 hr. Results: Teeth placed in conc. HCl and conc. HNO 3 dissolved completely after 8 hours, while that placed in conc. H 2 SO 4 retained its morphology and radiographic dimension even after 8 hours. Conclusion: Hence teeth can serve as a tool in identification (age estimation and sex determination of the victim when in contact with conc. H 2 SO 4 .

  12. Translucency measurements in teeth and dental materials

    Science.gov (United States)

    Rawicz, Andrew H.; Melnyk, Ivan; Kowalski, Pawel

    2003-06-01

    Exact color matching of dental restorative materials to vital teeth is a difficult task. There are several reasons for this difficulty and they will be elaborated upon in the presentation. One of the most important reasons is the fact that teeth, as well as dental restorative materials are translucent, and thus the color impression is a product of light scattering, back scattering, transmission, and spectral modifications inside of these objects. Classic colorimetry is insufficient to provide an exact color match. Additional information about the translucency factor of the considered object (material and geometry) is necessary to provide full reproducibility. Translucency has a direct effect on perceived brightness. In this article we describe the TransluDent, a complementary product to ColorDent, which measures translucency of teeth and dental materials. TransluDent determines translucency by measuring light transmitted through an object and light scattered inside of the object. The translucency measurements were performed on two groups of subjects. One group consisted of people in their twenties and the second group of subjects was in fifties. For comparison several sets of dental shade-guides were also tested. The great discrepancy in translucency factor between human teeth and popular on the market shades may explain difficulty in color matching of dental restorative materials to teeth.

  13. Construction of an integrated welfare assessment system (MacWel) for Macaques (Macaca spp.) in human husbandry

    DEFF Research Database (Denmark)

    Kirchner, Marlene; Bakker, Jaco

    2015-01-01

    The paper describes the construction procedure of an assessment protocol for Macaques (Macaca spp.). The authors have chosen an integrative approach, currently frequently used for the construction of such protocols with a clear preference for animal-based parameters to assess the welfare states o...

  14. Rotary endodontics in primary teeth - A review.

    Science.gov (United States)

    George, Sageena; Anandaraj, S; Issac, Jyoti S; John, Sheen A; Harris, Anoop

    2016-01-01

    Endodontic treatment in primary teeth can be challenging and time consuming, especially during canal preparation, which is considered one of the most important steps in root canal therapy. The conventional instrumentation technique for primary teeth remains the "gold-standard" over hand instrumentation, which makes procedures much more time consuming and adversely affects both clinicians and patients. Recently nickel-titanium (Ni-Ti) rotary files have been developed for use in pediatric endodontics. Using rotary instruments for primary tooth pulpectomies is cost effective and results in fills that are consistently uniform and predictable. This article reviews the use of nickel-titanium rotary files as root canal instrumentation in primary teeth. The pulpectomy technique is described here according to different authors and the advantages and disadvantages of using rotary files are discussed.

  15. Extreme strength observed in limpet teeth

    Science.gov (United States)

    Barber, Asa H.; Lu, Dun; Pugno, Nicola M.

    2015-01-01

    The teeth of limpets exploit distinctive composite nanostructures consisting of high volume fractions of reinforcing goethite nanofibres within a softer protein phase to provide mechanical integrity when rasping over rock surfaces during feeding. The tensile strength of discrete volumes of limpet tooth material measured using in situ atomic force microscopy was found to range from 3.0 to 6.5 GPa and was independent of sample size. These observations highlight an absolute material tensile strength that is the highest recorded for a biological material, outperforming the high strength of spider silk currently considered to be the strongest natural material, and approaching values comparable to those of the strongest man-made fibres. This considerable tensile strength of limpet teeth is attributed to a high mineral volume fraction of reinforcing goethite nanofibres with diameters below a defect-controlled critical size, suggesting that natural design in limpet teeth is optimized towards theoretical strength limits. PMID:25694539

  16. Dietary Variation of Long Tailed Macaques (Macaca fascicularis in Telaga Warna, Bogor, West Java

    Directory of Open Access Journals (Sweden)

    Sarah Nila

    2014-03-01

    Full Text Available The genus Macaca, member of sub-family Cercopithecinae, is the most widely distributed non-human primates in Asian countries. The habitats are strongly influence the dietary variation of the populations. The dietary variation of the macaques reflect ecological plasticity in coping with differences both in availability and abundance of food. The macaques are plastic in taking any kind of food that available in their home range and adjust their behaviour according to its abundance. Here, we present the dietary variation of long-tailed macaques (Macaca fascicularis in the high altitude rain forest of Telaga Warna, West Java, Indonesia. The proportion of their food from natural sources is greater than those from visitors. The natural food consisted of plants, small animals (insects and earthworm, fungi and water from lake. The plant food comprised of 29 species plus a few mosses. The frequency of eating artificial food was influenced by visitors who come for picnic. In this site, the macaques learned that the visiting of tourists is identical with food.

  17. Pharmacokinetics of tramadol following intravenous and oral administration in male rhesus macaques (Macaca mulatta)

    Science.gov (United States)

    Kelly, Kristi R.; Pypendop, Bruno H.; Christe, Kari L.

    2014-01-01

    Recently, tramadol and its active metabolite, O-desmethyltramadol (M1), have been studied as analgesic agents in various traditional veterinary species (e.g. dogs, cats, etc.). This study explores the pharmacokinetics of tramadol and M1 after intravenous (IV) and oral (PO) administration in rhesus macaques (Macaca mulatta), a nontraditional veterinary species. Rhesus macaques are Old World monkeys that are commonly used in biomedical research. Effects of tramadol administration to monkeys are unknown, and research veterinarians may avoid inclusion of this drug into pain management programs due to this limited knowledge. Four healthy, socially-housed, adult male rhesus macaques (Macaca mulatta) were used in this study. Blood samples were collected prior to, and up to 10 h post tramadol administration. Serum tramadol and M1 were analyzed using liquid chromatography-mass spectrometry. Noncompartmental pharmacokinetic analysis was performed. Tramadol clearance was 24.5 (23.4-32.7) mL/min/kg. Terminal half-life of tramadol was 111 (106-127) min IV and 133 (84.9-198) min PO. Bioavailability of tramadol was poor [3.47% (2.14-5.96%)]. Maximum serum concentration of M1 was 2.28 (1.88-2.73) ng/mL IV and 11.2 (9.37-14.9) ng/mL PO. Sedation and pruritus were observed after IV administration (180 words). PMID:25488714

  18. Pharmacokinetics of tramadol following intravenous and oral administration in male rhesus macaques (Macaca mulatta).

    Science.gov (United States)

    Kelly, K R; Pypendop, B H; Christe, K L

    2015-08-01

    Recently, tramadol and its active metabolite, O-desmethyltramadol (M1), have been studied as analgesic agents in various traditional veterinary species (e.g., dogs, cats, etc.). This study explores the pharmacokinetics of tramadol and M1 after intravenous (IV) and oral (PO) administration in rhesus macaques (Macaca mulatta), a nontraditional veterinary species. Rhesus macaques are Old World monkeys that are commonly used in biomedical research. Effects of tramadol administration to monkeys are unknown, and research veterinarians may avoid inclusion of this drug into pain management programs due to this limited knowledge. Four healthy, socially housed, adult male rhesus macaques (Macaca mulatta) were used in this study. Blood samples were collected prior to, and up to 10 h post-tramadol administration. Serum tramadol and M1 were analyzed using liquid chromatography-mass spectrometry. Noncompartmental pharmacokinetic analysis was performed. Tramadol clearance was 24.5 (23.4-32.7) mL/min/kg. Terminal half-life of tramadol was 111 (106-127) min IV and 133 (84.9-198) min PO. Bioavailability of tramadol was poor [3.47% (2.14-5.96%)]. Maximum serum concentration of M1 was 2.28 (1.88-2.73) ng/mL IV and 11.2 (9.37-14.9) ng/mL PO. Sedation and pruritus were observed after IV administration.

  19. Effects of age and sex on the hematology and blood chemistry of Tibetan macaques (Macaca thibetana).

    Science.gov (United States)

    Wu, Di; Yi, Yong; Sun, Fei; Zhou, Liang; Yang, Feng; Wang, Hongxing; Zhang, Guodong; Zhang, Yu Alex; Yue, Feng

    2014-01-01

    Tibetan macaques (Macaca thibetana), also known as Chinese stump-tailed macaques, are a threatened primate species. Although Tibetan macaques are Old World monkeys in the genus of Macaca, limited age- and sex-related physiologic data are available for this particular species. We used 69 apparently healthy Tibetan male and female macaques to explore the effect of age and sex on physiologic parameters. Somatometric measurements, biochemistry, and hematologic parameters were analyzed. Significant age-related differences were found for weight, BMI, RBC count, Hgb, Hct, neutrophils, eosinophil count, ALT, AST, ALP, GGT, creatine kinase (muscle and brain subtypes), LDH, α-amylase, creatinine, apolipoprotein A1, total protein, albumin, cholesterol, HDL, and potassium. Significant differences by sex were noted for weight, BMI, ALT, total bilirubin, and indirect bilirubin. An interaction between age and sex accounted for statistically significant differences in the values for weight, BMI, and lymphocyte and eosinophil counts. These physiologic data will provide veterinarians and researchers with important age- and sex-specific reference ranges for evaluating experimental results from Tibetan macaques.

  20. Sterilisation of extracted human teeth for educational use

    Directory of Open Access Journals (Sweden)

    Kumar M

    2005-01-01

    Full Text Available Sixty intact, non-carious and unrestored teeth extracted due to periodontal disease were used to determine the most effective method of sterilisation. The teeth were divided into six groups, each containing 10 teeth. Group 1 teeth were immersed in 10% formalin for seven days, group 2 teeth were immersed in 3% hydrogen peroxide for seven days, group 3 teeth were immersed in 2.6% sodium hypochlorite for seven days, group 4 teeth were boiled in water at 100°C for 20 minutes, group 5 teeth were autoclaved at 121°C at 15 lbs psi for 30 minutes, and group 6 teeth were immersed in normal saline for seven days. After the treatment, the teeth were individually inoculated into trypticase soy broth and incubated for 48 hours. A questionnaire survey was also conducted to determine the awareness of dental students regarding infection due to extracted human teeth and the common disinfection/sterilisation methods used. Autoclaving at 121°C, 15 lbs psi for 30 minutes and immersion in 10% formalin for seven days were effective in disinfecting/sterilising extracted human teeth. Chemicals such as 2.6% sodium hypochlorite, 3% hydrogen peroxide and boiling in water were not effective. The results indicate that autoclaving for 30 minutes or immersion in 10% formalin for seven days could be effectively used for disinfection/sterilisation of extracted human teeth.

  1. Simulation of a flow around biting teeth

    Science.gov (United States)

    Narusawa, Hideaki; Yamamoto, Eriko; Kuwahara, Kunio

    2008-11-01

    We simulated a flow around biting teeth. The decayed tooth is a disease that a majority of people are annoyed. These are often generated from a deep groove at occlusal surface. It is known that a person who bites well doesn't suffer from a decayed tooth easily. Biting forces reach as much as 60 kg/cm^2 by an adult male, and when chewing, upper and lower teeth approach to bite by those forces. The crushed food mixed with saliva becomes high viscosity fluid, and is pushed out of ditches of teeth in the direction of the cheek or the tongue. Teeth with complex three dimension curved surface are thought to form venturi at this time, and to generate big pressure partially. An excellent dental articulation will possibly help a natural generation of a flow to remove dental plaque, i.e. the cause of the decayed tooth. Moreover, the relation of this flow with the destruction of the filled metal or the polymer is doubted. In this research, we try to clarify the pressure distributions by this flow generation as well as its dynamics when chewing. One of our goals is to enable an objective design of the shape of the dental fillings and the artificial tooth. Tooth has a very small uneven ground and a bluff body. In this case, to calculate a computational numerical simulation to solve the Navier-Stokes equations three dimension Cartesian coordinate system is employed.

  2. Set Someone's Teeth on Edge

    Institute of Scientific and Technical Information of China (English)

    江河

    2002-01-01

    有些人听到刺耳的声音,或尝到酸溜溜的滋味时,会被刺激得牙齿颤动。“Set someone's teeth on edge”的成语由此产生,解释为使某人不安、烦躁甚至咬牙切齿。

  3. Rows of small teeth in Ziphioid whales

    NARCIS (Netherlands)

    Boschma, H.

    1951-01-01

    In Ziphioid Whales the toothrows as a rule have been subject to pronounced reduction, so that the number of teeth of fairly large size is restricted to one pair in the lower jaw. Even these often are concealed in the gum and then must be regarded as functionless, though especially in old males the t

  4. Elephant teeth from the atlantic continental shelf

    Science.gov (United States)

    Whitmore, F.C.; Emery, K.O.; Cooke, H.B.S.; Swift, D.J.P.

    1967-01-01

    Teeth of mastodons and mastodons have been recovered by fishermen from at least 40 sites on the continental shelf as deep as 120 meters. Also present are submerged shorelines, peat deposits, lagoonal shells, and relict sands. Evidently elephants and other large mammals ranged this region during the glacial stage of low sea level of the last 25.000 years.

  5. Ultrastructure of basement membranes in monkey and shark teeth at an early stage of development.

    Science.gov (United States)

    Sawada, Takashi

    2003-12-01

    The basement membrane, which separates the inner enamel epithelium from the dental papilla in the early stages of tooth development, is known to play a significant role in odontogenesis. In this review article, this basement membrane was described in detail based on our recent findings with the use of high-resolution electron microscopy. Tooth germs of a monkey (Macaca fuscata) and a shark (Cephaloscyllium umbratile) were processed for thin-section observations. During the early stage of development, the basement membrane of the inner enamel (dental) epithelium was composed of a lamina lucida, lamina densa, and much wider lamina fibroreticularis. At higher magnification, the lamina densa in both species was made up of a fine network of cords, which are generally the main constituents of the basement membranes. In the monkey tooth, the lamina fibroreticularis was rich in fibrils, which were now characterized as basotubules, 10-nm-wide microfibril-like structures. The space between the basotubules was filled with a cord network that extended from the lamina densa. Dental papilla cell processes were inserted into the lamina fibroreticularis, and their surface was closely associated with numerous parallel basotubules via 1.5- to 3-nm-wide filaments. In the shark tooth during its early stage of development, the basotubules were absent in the lamina fibroreticularis and only narrow extensions, 60-90 nm wide and 1-2 microm long, of the cord network of the lamina densa were present. The dental papilla cells were immobilized by means of the binding of their processes to the extensions. These results indicate that basement membranes in both monkey and shark teeth at early stage of development are specialized for functions as anchoring and firm binding, which are essential for the successful differentiation of the odontoblasts.

  6. Congenital oligodontia of the deciduous teeth and anodontia of the permanent teeth in a cat.

    Science.gov (United States)

    Vieira, Ana Luiza S; Ocarino, Natalia de M; Boeloni, Jankerle N; Serakides, Rogeria

    2009-02-01

    This report describes a rare case of congenital oligodontia of the deciduous teeth and anodontia of the permanent teeth in a cat. According to cat's veterinarian, the patient had only two deciduous upper canines and no permanent teeth had ever erupted. Post-mortem evaluation showed a complete absence of teeth in the oral cavity and inflammatory lesions were not found on the gums. Histopathological analysis of serial sections of maxilla and mandible revealed absence of odontogenic epithelium, inflammatory cells and odontoclastic resorptive lesions. Diagnosis was confirmed after both the establishment that there were no remaining dental structures and the exclusion of other relevant diseases that lead to tooth loss, such as periodontal disease, renal fibrous osteodystrophy, odontoclastic resorptive lesions, ectodermal dysplasia and trauma.

  7. Assessment of the periapical health of abutment teeth: A ...

    African Journals Online (AJOL)

    Assessment of the periapical health of abutment teeth: A retrospective ... Materials and Methods: In this study, the digital OPTGs of adult patients between ... Keywords: Abutment teeth, apical periodontitis, endodontics, epidemiology, radiology ...

  8. Traumatic intrusion of permanent teeth. Part 1. An epidemiological study of 216 intruded permanent teeth.

    Science.gov (United States)

    Andreasen, Jens Ove; Bakland, Leif K; Matras, Rannva C; Andreasen, Francis Meriam

    2006-04-01

    An epidemiological study of traumatic intrusion of permanent teeth was performed on 216 teeth in 151 patients treated over a 50-year period at a major trauma center in Denmark (Copenhagen). This analysis showed that intrusion of permanent teeth was of rare injury only affecting 1.9% of traumatic injuries involving permanent teeth. The main etiologic factor appeared to be falling which resulted in axial impacts on maxillary or mandibular teeth. The most common injury patterns were intrusion without additional injuries (33.5%) and intrusion with crown fractures (60.5%). A few cases were combinations of intrusion and either crown/root-fractures or root fractures (6%). Most often one tooth was intruded (46.3%), followed by two teeth (32.4% ) and three or more teeth (21.3%). The majority of intruded teeth were displaced 2-8 mm. The age group of 6-12 years of age was most frequently involved and boys appeared to experience intrusion injuries more frequently than girls, and at an earlier age. Maxillary central and lateral incisors are the primary victims of intrusions and this seems to be identical to other trauma types and is possibly related to the known exposure to impacts of maxillary incisors. The reliability of clinical findings, such as lack of mobility (81.8%), metallic percussion tone (72.5%), and no pain to percussion (66%) was reasonably high, whereas a radiographic feature such as the obliteration of the periodontal ligament space appeared to be only a partly reliable diagnostic tool (52%).

  9. An overlay partial denture to restore worn mandibular anterior teeth.

    Science.gov (United States)

    Samant, Asha; DeSciscio, Peter

    2014-01-01

    Restoring worn anterior mandibular teeth is a challenge, especially when teeth are small, esthetics are a concern, the long-term prognosis is questionable, and/or patient finances are an issue. This article describes an alternate treatment for a patient with a collapsed bite, missing posterior mandibular teeth, an ill-fitting complete maxillary denture with poor esthetics, and irregular, worn mandibular anterior teeth.

  10. Reduction of contact stresses using involute gears with asymmetric teeth

    OpenAIRE

    2015-01-01

    Asymmetrical involute gears have a different value of the operating pressure angle for right and left side of the gear. These teeth are suitable for one direction of rotation. Such teeth enable to change the length of the generating line. They enable to improve the value of reduced radii of curvature. Asymmetrical teeth allow reducing the values of Hertz's pressures, especially on the root of the teeth. Hertz pressures are directly related to the asymmetry.

  11. Modular Permanent Magnet Machines with Alternate Teeth Having Tooth Tips

    OpenAIRE

    Li, G. J.; Zhu, Z.Q.; Foster, M. P.; Stone, D. A.; Zhan, H.L.

    2015-01-01

    This paper presents single layer modular permanent magnet machines with either wound or unwound teeth with tooth tips. The structures with wound teeth having tooth tips are suitable for modular machines with slot number higher than pole number to compensate for the drop in winding factor due to the flux gaps in alternate stator teeth, accordingly to maintain or even to increase their average torques. However, the structures with unwound teeth having tooth tips are suitable for modular machine...

  12. Natal teeth in an infant with congenital hypothyroidism

    Directory of Open Access Journals (Sweden)

    C Venkatesh

    2011-01-01

    Full Text Available Teeth erupting at birth are referred to as natal teeth. It is a common and benign finding in the neonatal period. However, they may be associated with genetic syndromes like Ellis Van Creveld syndrome and Hallermann-Streiff syndrome. We report here a case of natal teeth in an infant with congenital hypothyroidism.

  13. Dentinogenesis imperfecta - hardness and Young's modulus of teeth.

    Science.gov (United States)

    Wieczorek, Aneta; Loster, Jolanta; Ryniewicz, Wojciech; Ryniewicz, Anna M

    2013-01-01

    Dentinogenesis imperfecta type II (DI-II) is the most common dental genetic disease with reported incidence 1 in 8000. Elasticity and hardness of the enamel of teeth are important values which are connected with their resistance to attrition. It is hypothesized that values of physical properties for healthy teeth and teeth with DI-II are different. The aim of the study was to investigate some physical properties of teeth extracted from patients with DI-II in comparison with normal teeth. The material of the study was six teeth: three lower molars, with clinical signs of DI-II, which were extracted due to complications of pulp inflammation and three other lower molars which were extracted for orthodontic reasons - well formed, without any signs of pathology. The surfaces of DI-II and normal teeth were tested on the CSM Instruments Scratch Tester machine (producer CSEM Switzerland) by Oliver and Pharr method. The indenter used was Vicker's VG-73 diamond indenter. Additionally, the Scanning Electron Microscopy (SEM) analysis of the surface of the teeth with DI-II was made. Vickers hardness of the teeth with dental pathology (DI-II) was seven times smaller, and Young's modulus six times smaller than those of healthy teeth. The parameters of hardness and elasticity of enamel of teeth with clinical diagnosis of DI-II were very much smaller than in normal teeth and because of that can be responsible for attrition.

  14. An evaluation of factors associated with persistent primary teeth.

    Science.gov (United States)

    Aktan, Ali Murat; Kara, Isa; Sener, Ismail; Bereket, Cihan; Celik, Salih; Kirtay, Mustafa; Ciftçi, Mehmet Ertugrul; Arici, Nursel

    2012-04-01

    The aim of the present study was to investigate the reasons for the persistence of primary teeth and also use panoramic radiography to determine the characteristics of persistence teeth. Four-hundred and twenty-six panoramic radiographies, which diagnosed one or more retained primary teeth, were selected from 100,577 panoramic radiographic image files from nine clinics and six different cities in Turkey. The selected radiographies were evaluated to determine the reasons for the persistence of primary teeth; furthermore, this study analyzed the characteristics of the retained primary teeth including tooth type, number, location, and root resorption, and whether, or not, the primary teeth showed evidence of pathological conditions, such as periodontal problems, caries, ankylosis, infra-occlusions, or tipping of the adjacent permanent teeth. Six hundred and seventy-seven retained primary teeth were determined in 426 patients (148 males and 278 females). Retained primary teeth were found most frequently in the mandible rather than the maxilla and the left side was more frequently affected than the right side. Level 1 was found as a most frequently encountered root resorption level. Within the limitation of the present study, the most common type of persistent primary teeth seen on the dental arch were mandibular primary second molars, followed by maxillary primary canines. The most frequent reason for the persistence was the congenital absence of successors to the primary teeth, followed by impaction of the successor teeth.

  15. Analyses of 1100 supernumerary teeth in a nonsyndromic Turkish ...

    African Journals Online (AJOL)

    2015-03-02

    Mar 2, 2015 ... of deciduous teeth, delayed eruption of permanent teeth, ectopic ... incisors, cyst development, and root resorption of adjacent teeth.[12] The ... analysis of the largest number of ST cases in the literature. The aim of this study ...

  16. Recruitment and monitoring behaviors by leaders predict following in wild Barbary macaques (Macaca sylvanus

    Directory of Open Access Journals (Sweden)

    A. Seltmann

    2016-07-01

    collective movements in a group of wild Barbary macaques (Macaca sylvanus in the Middle Atlas, Morocco. The number of individuals displaying pre-departure behavior predicted the success of an initiation of a collective movement. Pauses of the first departing individual after departure enhanced following behavior and might have served as recruitment signal. However, the opposite was the case for back-glancing, which functions as a monitoring signal in other species. Because in our study frequently back-glancing individuals were also less socially integrated, back glances may better be interpreted as indicators of hesitation and insecurity. To successfully initiate a collective movement, it seemed to be sufficient for a socially integrated group member to take action when other group members signal their willingness prior to departure and to occasionally wait for the group while moving.

  17. Rosalie: the brazilian female monkey of Charcot Rosalie: a pequenina macaca brasileira de Charcot

    Directory of Open Access Journals (Sweden)

    Hélio A.G. Teive

    2005-09-01

    Full Text Available Jean-Martin Charcot, the father of Neurology, a very austere and reserved man that did not express affection freely for human being, had a profound affection to animals, particularly to a small female monkey, called "Rosalie", which came from Brazil and was a gift of Dom Pedro II to Charcot.Jean-Martin Charcot, considerado o pai da Neurologia, foi um homem de aspecto austero e reservado, que tinha dificuldades de expressar os seus sentimentos para outros seres humanos. Contudo ele tinha profunda afeição por animais, particularmente por uma pequena macaca, chamada de "Rosalie", oriunda do Brasil e que foi um presente dado a ele por Dom Pedro II.

  18. Effect of radiation and age on immunoglobulin levels in rhesus monkeys (Macaca mulatta)

    Science.gov (United States)

    Stone, W. H.; Saphire, D. G.; Hackleman, S. M.; Braun, A. M.; Pennington, P.; Scheffler, J.; Wigle, J. C.; Cox, A. B.

    1994-01-01

    We report the results of a study on the immunoglobulin levels of rhesus monkeys (Macaca mulatta) in a colony consisting of the survivors of monkeys that received a single whole-body exposure to protons, electrons or X rays between 1964 and 1969. This colony has been maintained to assess the long-term effects of ionizing radiation on astronauts and high-flying pilots. Of the original 358 monkeys that were retained for lifetime studies, 129 (97 irradiated and 32 controls) were available for our study. We found no significant difference between the irradiated and control monkeys in mean levels of IgA, IgG and IgM, irrespective of the radiation treatment. The availability of these aged monkeys provided a unique opportunity to compare their immunoglobulin levels to those of other monkeys of various ages, and thus assess the effect of age on immunoglobulin levels. We found that only the IgA levels increase with age.

  19. Effects of feeding selenium deficient diets to rhesus monkeys (Macaca Mulatta)

    Energy Technology Data Exchange (ETDEWEB)

    Butler, J.A.; Whanger, P.D.; Patton, N.M.

    1988-02-01

    Pregnant rhesus monkeys (Macaca mulatta) were fed either selenium (Se) deficient or Se supplemented diets with adequate vitamin E. Except for some cardiac irregularities in the first babies born to these females, no physiological disorders due to Se deficiency were seen in a subsequent offspring. Plasma and erythrocyte glutathione peroxidase activities and blood Se levels increased in the Se supplemented monkeys but decreased in the deficient ones. The data indicated that hair Se levels reflect long term exposure to this element. In a very preliminary experiment, evidence was obtained to indicate that dietary protein deficiency along with Se deficiency will generate cardiomyopathic lesions characteristic of Se deficiency. It is hypothesized that, in addition to Se deficiency, another dietary deficiency (or abnormality) is necessary to produce Se deficiency lesions in higher primates. Higher glutathione transferase (or non-Se glutathione peroxidase) activity in tissues of rhesus monkeys may account for this resistance.

  20. Campylobacter pylori isolated from the stomach of the monkey, Macaca nemestrina.

    Science.gov (United States)

    Bronsdon, M A; Schoenknecht, F D

    1988-09-01

    Campylobacter pylori was isolated from the gastric mucosa in 6 of 24 pigtailed macaques (Macaca nemestrina) examined by gastric biopsy and culture; 3 isolates were recovered during gastroendoscopy, and 3 were recovered at necropsy. The isolates were morphologically and biochemically similar to the human type strain NCTC 11638, differing only in colony diameter, pigmentation, and rate of growth. Identity of the isolates was confirmed by whole-genomic DNA-DNA hybridization with the type strain. Colonization of the monkey stomachs was associated with hypochlorhydria and histologic features resembling type B chronic gastritis in humans. Host animals exhibited no morbid clinical effects of colonization, although endoscopy revealed inflammation, erythema, and friable tissue in some animals. The discovery of C. pylori occurring spontaneously in M. nemestrina extends the known range of the hosts of the organism and offers the possibility of a natural or experimental model of the infection in monkeys.

  1. AKTIVITAS HARIAN KERA EKOR PANJANG (Macaca fascicularis DI TAMAN WISATA ALAM SANGEH, KABUPATEN BADUNG, BALI

    Directory of Open Access Journals (Sweden)

    Komang Gede Wahyu Saputra

    2015-02-01

    Full Text Available Penelitian tentang aktivitas harian kera ekor panjang (Macaca fascicularis telah dilakukan di Taman Wisata Alam Sangeh, Kabupaten Badung, Bali dari bulan Oktober – Desember 2012. Penelitian ini bertujuan untuk mengetahui perilaku harian kera ekor panjang (M.  fascicularis di Taman Wisata Alam Sangeh. Penelitian perilaku harian kera dilakukan dengan metode Focal Animal Sampling. Data yang terkumpul dari berbagai jenis perilaku di analisa secara deskriptif kuantitatif. Hasil penelitian menunjukan bahwa frekuensi aktivitas harian kera ekor panjang didominasi oleh perilaku bergerak, kemudian berturut-turut diikuti oleh perilaku istirahat, makan, grooming, mendekap di dada, objek manipulasi, cuddling, agresif. sedangkan perilaku yang paling jarang dilakukan adalah kawin. Berdasarkan jenis kelamin individu dewasa, perilaku istirahat, makan, bergerak, agresif, objek manipulasi dan kawin didominasi oleh jantan sedangkan perilaku mendekap di dada, cuddling, dan grooming di dominasi oleh betina.

  2. Pulpectomy procedures in primary molar teeth

    Directory of Open Access Journals (Sweden)

    Hany Mohamed Aly Ahmed

    2014-01-01

    Full Text Available Premature loss of primary molars can cause a number of undesirable consequences including loss of arch length, insufficient space for erupting premolars and mesial tipping of the permanent molars. Pulpectomy of primary molar teeth is considered as a reasonable treatment approach to ensure either normal shedding or a long-term survival in instances of retention. Despite being a more conservative treatment option than extraction, efficient pulpectomy of bizarre and tortuous root canals encased in roots programmed for physiologic resorption that show close proximity to developing permanent tooth buds presents a critical endodontic challenge. This article aims to provide an overview of this treatment approach, including partial and total pulpectomy, in primary molar teeth. In addition, the recommended guidelines that should be followed, and the current updates that have been developed, while commencing total pulpectomy in primary molars are discussed.

  3. Teaching parents to look after children's teeth.

    Science.gov (United States)

    Lloyd, S

    1994-03-01

    Children's toothpastes with fluoride help to prevent decay, but parents should ask their dentist before giving fluoride supplements to children. Overdosage is harmful. Sugars eaten as part of a meal do less harm to teeth than those eaten frequently as snacks. Sugar-free infant drinks and children's confectionery are now on the market and are more "tooth friendly". Look out for the "happy tooth" symbol. Babies can be registered with NHS dentists as soon as the first teeth start to come through, and should be taken regularly to the dentist throughout childhood. Under the NHS scheme, dentists are paid a capitation fee to provide continuing preventive care and treatment for children free of charge.

  4. Dental Trauma: An inside to Avulsion Teeth

    OpenAIRE

    Mendes PhD, Beatriz

    2015-01-01

    Several studies shows that a wide range from 3-16% of dentoalveolar traumatic injuries result in avulsion. The ideal treatment for avulsion would be the reimplantation of the tooth. Thus, it is recommended to replant the tooth as quickly as possible. However, immediate repositioning of teeth is not always possible, so the choice of a suitable storage medium for maintenance of Periodontal Ligament cell viability is of extreme importance for the success of replantation. At the present article a...

  5. Reconstruction of endodontically treated teeth: intraradicular retainers

    Directory of Open Access Journals (Sweden)

    Luciano Bonatelli Bispo

    2008-01-01

    Full Text Available There are many ways of restoring endodontically treated teeth. The quantity and quality of the dental remainder after endodontic treatment is questionable in terms of clinical longevity, not because of the coronal opening and therapy in themselves, but because of the destruction inherent to teeth affected by fractures and invasive carious processes. There are many commercial brands of posts and marketing artifices with the goal of maximizing resistance to masticatory forces. However, the major complexity found with regard to the definitive restoration is the doubt whether to insert a prefabricated post, cast metal or porcelain core as filling core. However, nothing is feasible if the parameters said to be safe were not used and the minimum mechanical requirements were not demanded. Growing commercial demand leads to unrestrained confusion in professionals that end up forgetting about or ignoring the minimum criteria demandable for a favorable prognosis. Compliance with the biomechanical bases is the most important parameter for increasing the quality of the intraradicular retainer. The aim of this study is to present basic techniques for more reliable restorations, maximizing the quality of the dental remainder when making extensive restorations that use intraradicular retainers in endodontically treated teeth.

  6. Sexual dimorphism in permanent teeth of modern Greeks.

    Science.gov (United States)

    Zorba, Eleni; Moraitis, Konstantinos; Manolis, Sotiris K

    2011-07-15

    Sex determination is considered an important step in reconstructing the biological profile of unknown individuals from a forensic context. Forensic anthropologists have long used teeth as an additional tool for sex determination as they resist postmortem destruction. In this case the use of population-specific data is necessary since sexual dimorphism varies between different populations. Currently there are no odontometric standards for determining sex in Greek populations. The purpose of this study is to examine the degree of sexual dimorphism in permanent teeth of modern Greeks. A total of 839 permanent teeth in 133 individuals (70 males and 63 females) from the Athens Collection were examined. Mesiodistal and buccolingual crown and cervical diameters of both maxillary and mandibular teeth were measured. It was found that males have bigger teeth than females and in 65 out of 88 dimensions measured, male teeth exceeded female teeth significantly (P<0.05). Canines were the most dimorphic teeth followed by first premolars, maxillary second premolar and mandibular second molar. Although other teeth were also sexually dimorphic they did not have a statistically significant difference in all dimensions. The most dimorphic dimension was buccolingual cervical diameter followed by buccolingual crown diameter. A comparison of sexual dimorphism in teeth between different populations showed that it differs among different groups. European population groups presented the highest degree of sexual dimorphism in teeth whereas Native South Americans the lowest.

  7. Microprobe analysis of teeth by synchrotron radiation: environmental contamination

    Energy Technology Data Exchange (ETDEWEB)

    Pinheiro, T. E-mail: murmur@itn1.itn.pt; Carvalho, M.L.; Casaca, C.; Barreiros, M.A.; Cunha, A.S.; Chevallier, P

    1999-09-02

    An X-ray fluorescence set-up with microprobe capabilities, installed at the Laboratoire pour l'Utilisation du Rayonnement Electromagnetique (LURE) synchrotron (France) was used for elemental determination in teeth. To evaluate the influence of living habits in dental elemental composition nine teeth collected post-mortem were analysed, five from a miner and four from a fisherman. All teeth from the fisherman were healthy. From the miner some teeth were carious and one of them was filled with metallic amalgam. Teeth were sliced under the vertical plane and each slice was scanned from the root to the enamel for elemental profile determination. The synchrotron microprobe resolution was of 100 {mu}m and incident photons of 18 keV energy were used. The elemental concentration values found suggest heterogeneity of the teeth material. Moreover, the distinct profiles for Mn, Sr, Br and Pb were found when teeth from the miner and from the fisherman are compared which can be associated with dietary habits and environmental influence. Higher concentrations of Mn and Sr were found for the fisherman teeth. In addition, Br was only observed in this group of teeth. Pb levels are higher for the miner teeth in particular for dentine regions. The influence of amalgam, such as, increase of Zn and Hg contents in the teeth material, is only noticed for the immediate surroundings of the treated cavity.

  8. Resistance to cyclic loading of teeth restored with posts

    DEFF Research Database (Denmark)

    Sahafi, A; Peutzfeldt, A; Ravnholt, G

    2005-01-01

    This in vitro study evaluated the effect of presence of post, presence of core, and of shape, type, and surface treatment of posts on resistance to cyclic loading of crowned human teeth. For all teeth, crowns designed without ferrule were cast in sterling silver and luted with resin cement (Panavia...... F). Each tooth underwent cyclic loading of 600 N at two loads per second until failure. Teeth that had only been crowned showed significantly higher resistance to cyclic loading than teeth with cores or with post and cores. No significant differences were found between teeth restored with cores only...... or with post and cores, irrespective of surface-treatment of the posts. Teeth restored with parallel-sided cast post (ParaPost XP) and cores showed significantly higher resistance to cyclic loading than teeth with either tapered cast posts or untreated prefabricated posts of titanium alloy (ParaPost XH...

  9. Shark teeth as edged weapons: serrated teeth of three species of selachians.

    Science.gov (United States)

    Moyer, Joshua K; Bemis, William E

    2017-02-01

    Prior to European contact, South Pacific islanders used serrated shark teeth as components of tools and weapons. They did this because serrated shark teeth are remarkably effective at slicing through soft tissues. To understand more about the forms and functions of serrated shark teeth, we examined the morphology and histology of tooth serrations in three species: the Tiger Shark (Galeocerdo cuvier), Blue Shark (Prionace glauca), and White Shark (Carcharodon carcharias). We show that there are two basic types of serrations. A primary serration consists of three layers of enameloid with underlying dentine filling the serration's base. All three species studied have primary serrations, although the dentine component differs (orthodentine in Tiger and Blue Sharks; osteodentine in the White Shark). Smaller secondary serrations are found in the Tiger Shark, formed solely by enameloid with no contribution from underlying dentine. Secondary serrations are effectively "serrations within serrations" that allow teeth to cut at different scales. We propose that the cutting edges of Tiger Shark teeth, equipped with serrations at different scales, are linked to a diet that includes large, hard-shelled prey (e.g., sea turtles) as well as smaller, softer prey such as fishes. We discuss other aspects of serration form and function by making analogies to man-made cutting implements, such as knives and saws. Copyright © 2016 Elsevier GmbH. All rights reserved.

  10. Impact of human pressure and forest fragmentation on the Endangered Barbary macaque Macaca sylvanus in the Middle Atlas of Morocco

    OpenAIRE

    Ménard, Nelly; Rantier, Yann; Foulquier, Adrien; Qarro, Mohamed; Chillasse, Lahcen; Vallet, Dominique; Pierre, Jean-Sébastien; Butet, Alain

    2014-01-01

    International audience; Overexploitation of forests by humans can lead to highly fragmented populations of forest-dependent species that have poor dispersal abilities. We tested the influence of habitat quality, landscape structure and human pressure on densities of the Barbary macaque Macaca sylvanus in the largest wild population, in the Middle Atlas of Morocco. We surveyed 14 forest fragments of 5-142 km2 that are separated from each other by an inhospitable matrix. We estimated the habita...

  11. Teething myths among nursing mothers in North-Western Nigeria

    Directory of Open Access Journals (Sweden)

    Ibrahim Aliyu

    2015-01-01

    Full Text Available Background: Teething has over the years been associated with complains of systemic symptoms from parents, and at times are over treated by health-care professionals. This study seeks to determine common teething complaints reported by nursing mothers. Materials and Methods: This study was multicenter involving 224 nursing mothers. It was cross-sectional and questionnaire-based relevant information collected were: The socio demographic characteristics, knowledge of teething and myths associated with teething, and the attitude of nursing mothers toward the use of teething remedies. Results: Two hundred and three (90.62% of them believed teething caused symptoms; common complaints that were attributed to teething by mothers were diarrhea, vomiting, increased salivation; however, fever was the predominant complaint, and their parents were the most common source of information on teething in 50% of them, while only a mother (0.4% was informed on the process of teething at the hospital. Furthermore, the number of children did not affect the desire to seek for medical care for teething symptoms. Common remedies used were as follows: 59 (26.3% nursing mothers used teething syrup, 43 (19.2% nursing mothers used teething powder, 16 (7.2% of them used traditional herbs while 8(3.6% of them used multiple preparations; however 91 (40.6% of them did not use any remedy. One hundred and seven (47.8% of the mothers believed that these remedies worked, 67 (29.9% of them disagreed while 50 (22.3% were not sure of their efficacy. Conclusion: Parents should be educated on normal expectations of the teething process; and not to undermine the seriousness of illnesses erroneously attributed to teething.

  12. Collection of Macaca fascicularis cDNAs derived from bone marrow, kidney, liver, pancreas, spleen, and thymus

    Directory of Open Access Journals (Sweden)

    Kameoka Yosuke

    2009-09-01

    Full Text Available Abstract Background Consolidating transcriptome data of non-human primates is essential to annotate primate genome sequences, and will facilitate research using non-human primates in the genomic era. Macaca fascicularis is a macaque monkey that is commonly used for biomedical and ecological research. Findings We constructed cDNA libraries of Macaca fascicularis, derived from tissues obtained from bone marrow, liver, pancreas, spleen, and thymus of a young male, and kidney of a young female. In total, 5'-end sequences of 56,856 clones were determined. Including the previously established cDNA libraries from brain and testis, we have isolated 112,587 cDNAs of Macaca fascicularis, which correspond to 56% of the curated human reference genes. Conclusion These sequences were deposited in the public sequence database as well as in-house macaque genome database http://genebank.nibio.go.jp/qfbase/. These data will become valuable resources for identifying functional parts of the genome of macaque monkeys in future studies.

  13. Cleidocranial dysplasia presenting with retained deciduous teeth and impacted permanent and supernumerary teeth

    Directory of Open Access Journals (Sweden)

    Mahalakshmi Ikkanur Puttaranganaik

    2014-01-01

    Full Text Available Cleidocranial dysplasia is a disease that occurs secondary to a dominant autosomal inheritance. There is no predilection for any genre or ethnic group. As there is a delay in the eruption and/or absence of permanent teeth, the patients usually report to a dental surgeon for replacement of the missing teeth. This condition is characterized by several cranial malformations and underdevelopment, absence of clavicles, and multiple impacted supernumerary and permanent teeth. The diagnosis of the condition is usually based on the presence of the above-mentioned main features and on clinical and familial evidence. Here we report a rare case of cleidocranial dysplasia in a male patient, having most of the characteristic features of this syndrome.

  14. A Diagnostic and Therapeutic Algorithm for Impacted Teeth for Plastic Surgeons: Outcomes of 242 Extracted Teeth

    Directory of Open Access Journals (Sweden)

    Nebil Yeşiloğlu

    2016-09-01

    Full Text Available Objective: Impacted teeth are important for plastic surgeons that frequently perform maxillofacial operations because of their tendency to affect dental occlusion, and thus, cephalometric results. Moreover, severe complications are also caused by the tooth and its surgical removal. In this study, retrospective analysis of 242 extracted teeth and 24 extracted roots was performed and an algorithmic approach to different types and the localizations of impacted teeth was presented. Possible complications and salvage procedures were also discussed. Material and Methods: A retrospective analysis of 128 patients who underwent impacted teeth removal surgery between 2013 and 2015 was performed. Mean age was 26 years (Range: 18–42 years, and the female to male ratio was 39/89. Sixteen of the patients were operated under regional nerve block, whereas the remaining were operated under general anesthesia. In 107 patients, the whole tooth was removed, whereas the residual root of the tooth was removed in 21 patients. In 89 patients, bone interventions like the creation of bone window or peridental milling to loosen the tooth were needed, whereas only oral mucosal incisions were performed in the remaining patients. Results: The most common onset symptom was localized pain, and the most common complications were swelling and edema. The most common extracted tooth was the mandibular 3rd molar. Lower lip hypoesthesia, which was continued up to eight months, was encountered in six patients who underwent mandibular 3rd molar extraction. Conclusion: In our opinion, a wide range of possible complications secondary to impacted teeth surgery makes them important for plastic surgeons who are more experienced than other disciplines, and learning teeth extraction is essential to learn in plastic surgery specialty training.

  15. A review on anterior teeth restorations

    Directory of Open Access Journals (Sweden)

    Gaurav Solanki

    2014-12-01

    Full Text Available Restorations of teeth have been a need of time since very long. As the time have passed, there have been different advances in the field of restorative materials and tooth restorations. Many newer restorative materials are now available to us for the purpose of tooth restorations still some of the older materials are materials of choice for a sector of society. This article focuses on few such restorative materials and also tells us about a few patents granted in such field.

  16. Tutankhamun's Dentition: The Pharaoh and his Teeth.

    Science.gov (United States)

    Pausch, Niels Christian; Naether, Franziska; Krey, Karl Friedrich

    2015-01-01

    Tutankhamun was a Pharaoh of the 18th Dynasty (New Kingdom) in ancient Egypt. Medical and radiological investigations of his skull revealed details about the jaw and teeth status of the mummy. Regarding the jaw relation, a maxillary prognathism, a mandibular retrognathism and micrognathism have been discussed previously. A cephalometric analysis was performed using a lateral skull X-ray and a review of the literature regarding King Tutankhamun´s mummy. The results imply diagnosis of mandibular retrognathism. Furthermore, third molar retention and an incomplete, single cleft palate are present.

  17. Newer methods of extraction of teeth

    Directory of Open Access Journals (Sweden)

    MHendra Chandha

    2016-06-01

    Full Text Available Atraumatic extraction methods are deemed to be important to minimize alveolar bone loss after tooth extraction. With the advent of such techniques, exodontia is no more a dreaded procedure in anxious patients. Newer system and techniques for extraction of teeth have evolved in the recent few decades. This article reviews and discusses new techniques to make simple and complex exodontias more efficient with improved patient outcomes. This includes physics forceps, powered periotome, piezosurgery, benex extractor, sonic instrument for bone surgery, lasers.

  18. Partial pulpotomy in young permanent teeth with deep carious lesions.

    Science.gov (United States)

    Mejàre, I; Cvek, M

    1993-12-01

    The material comprised 37 young posterior teeth with deep carious lesions and exposed pulps, treated with partial pulpotomy and dressed with calcium hydroxide. The teeth were divided into two groups. Group 1 consisted of 31 teeth with no clinical or radiographic symptoms before treatment, Group 2 of 6 teeth with temporary pain, widened periodontal space periapically and/or productive osteitis, i.e. increased density of the surrounding alveolar bone. After an observation time of 24 to 140 months (mean = 56 months), healing had occurred in 29 of 31 teeth in Group 1 (93.5%) and in 4 of 6 teeth in Group 2. It was concluded that the present, as well as previously reported results indicate that partial pulpotomy may be an adequate treatment for young permanent molars with a carious exposure, although more studies are needed before the treatment can be recommended for routine clinical use.

  19. Complex aesthetic treatment on anterior maxillary teeth with malposition

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    Febriastuti Febriastuti

    2008-12-01

    Full Text Available Background: Complex aesthetic treatment on anterior teeth involves more than one caries tooth with malformed shape and malposition. Purpose: The purpose of this paper is to find the alternative treatment for anterior maxillary teeth with malposition. Case: In this case, a 25 year-old man with a peg shaped teeth and caries on several teeth and malposition can be treated with complex aesthetic treatment. Case management: Endodontic pulpectomy treatment on anterior maxillary teeth and post construction with splint porcelain fused to metal crowns on 11, 12, and 21, 22 to correct the shape and position into normal position. Conclusion: Malformed and malpositioned teeth with caries can be treated with complex aesthetic treatment.

  20. Histological appearance of postmortem pink teeth: Report of two cases.

    Science.gov (United States)

    Gowda, Bk Charan; Sivapathasundharam, B; Chatterji, Ananjan; Chatterji, B L

    2015-01-01

    This article presents images and histological changes in the dentin of two cases involving posmortem pink teeth. Postmortem pink teeth were noted among two deceased male individuals. Pink teeth were noted during autopsy examination after twelve days in one corpse, and eight days following death in the second case. During the examination decomposition and putrefaction of the body was noted. Cause of death was drowning in one case and haemorrhages and shock in another. A central incisor tooth was obtained from each body. Both teeth exhibited a pink appearance and the intensity was more pronounced in the cervical region. Although pink teeth can be noted in death due to asphyxia, carbon monoxide poisoning and so on, it is necessary to study the exact role behind the appearance of pink teeth and try to incorporate the finding medico legally.

  1. Bacteriological analysis of necrotic pulp and fistulae in primary teeth

    OpenAIRE

    FABRIS, Antônio Scalco; Nakano, Viviane; Avila-Campos,Mario Júlio

    2014-01-01

    Objectives: Primary teeth work as guides for the eruption of permanent dentition, contribute for the development of the jaws, chewing process, preparing food for digestion, and nutrient assimilation. Treatment of pulp necrosis in primary teeth is complex due to anatomical and physiological characteristics and high number of bacterial species present in endodontic infections. The bacterial presence alone or in association in necrotic pulp and fistula samples from primary teeth of boys and gir...

  2. Restoring primary anterior teeth: updated for 2014.

    Science.gov (United States)

    Waggoner, William F

    2015-01-01

    The purpose of this paper was to review the current literature associated with the techniques and materials for the restoration of primary anterior teeth and make clinical recommendations based upon the available literature. A variety of esthetic restorative materials are available to utilize for restoring primary incisors. Awareness of the specific strengths, weakness, and properties of each material can enhance the clinician's ability to make the best choice of selection for each individual situation. Intracoronal restorations of primary teeth may utilize resin composites, glass ionomer cements, resin-modified ionomers, or polyacid-modified resins. Full coronal restoration of primary incisors may be indicated for a number of reasons. Crowns available for restoration of primary incisors include those that are directly bonded onto the tooth, which generally are a resin material, and crowns that are luted onto the tooth and are either some type of stainless steel or zirconia crown. There is insufficient controlled, clinical data to suggest that one type of restoration is superior to another. Operator preferences, esthetic demands by parents, the child's behavior, the amount of tooth structure remaining, and moisture and hemorrhage control are all variables that affect the decision and ultimate outcome of whatever restorative solution is chosen.

  3. Applying tribology to teeth of hoofed mammals.

    Science.gov (United States)

    Schulz, Ellen; Calandra, Ivan; Kaiser, Thomas M

    2010-01-01

    Mammals inhabit all types of environments and have evolved chewing systems capable of processing a huge variety of structurally diverse food components. Surface textures of cheek teeth should thus reflect the mechanisms of wear as well as the functional traits involved. We employed surface textures parameters from ISO/DIS 25178 and scale-sensitive fractal analysis (SSFA) to quantify dental wear in herbivorous mammals at the level of an individual wear enamel facet. We evaluated cheek dentitions of two grazing ungulates: the Blue Wildebeest (Connochaetes taurinus) and the Grevy's Zebra (Equus grevyi). Both inhabit the east African grassland savanna habitat, but they belong to fundamentally different taxonomic units. We tested the hypothesis that the foregut fermenting wildebeest and the hindgut fermenting zebra show functional traits in their dentitions that relate to their specific mode of food-composition processing and digestion. In general, surface texture parameters from SSFA as well as ISO/DIS 25178 indicated that individual enamel ridges acting as crushing blades and individual wear facets of upper cheek teeth are significantly different in surface textures in the zebra when compared with the wildebeest. We interpreted the complexity and anisotropy signals to be clearly related to the brittle, dry grass component in the diet of the zebra, unlike the wildebeest, which ingests a more heterogeneous diet including fresh grass and herbs. Thus, SSFA and ISO parameters allow distinctions within the subtle dietary strategies that evolved in herbivorous ungulates with fundamentally different systematic affinities but which exploit a similar dietary niche.

  4. MULTIPLE RETAINED TEETH IN MANDIBLE: A Case Report

    OpenAIRE

    Cvetan Cvetanov; Ivan Chenchev; A. Bakardjiev

    2010-01-01

    Purpose: The aim of this science report is to show a rare case of multiple impacted teeth at adult patient and our propose clinical approach.Materials and methods: The clinical case is showed from adult man /64-year old/ with multiple impacted teeth (6 impacted teeth in the anterior place on the mandible) were not suggestive of any syndrome or metabolic disorder. The extraction of the impacted teeth was made on two stage with piezosurgery unit under local anaesthesia. For prevention of post...

  5. Prognosis of teeth in the line of jaw fractures.

    Science.gov (United States)

    Aulakh, Kamaldeep K; Gumber, Tejinder Kaur; Sandhu, Sumeet

    2017-04-01

    The decision as to whether teeth in the line of jaw fractures should be extracted or retained remains a controversial issue. The aim of this study was to assess the prognosis of teeth directly in the line of, and adjacent to, jaw fracture sites. The study consisted of 50 patients with facial fractures in the dentate region, the diagnosis of which was made on the basis of clinical and radiographic examinations. A total of 124 teeth were present in 69 fracture sites (50 patients), of which 89 teeth were evaluated both, clinically (tooth mobility, pocket depth, pulp sensibility) and with periapical radiographs (degree of fracture displacement, marginal bone loss, root resorption). The results revealed that 61.9% of teeth in directly in the line of fractures showed no response to electric pulp testing compared with 48.9% teeth adjacent to fractures. The maximum frequency of non-responsive teeth was observed in Type I fractures followed by Type II fractures. Response to pulp tests was highly significant at postoperative 3- and 6-month periods (Wilcoxon's test). There was continuous reduction in the measurement for mean pocket depth at both test and control sites of teeth. The measurement of marginal bone levels of teeth in the line of fractures revealed a significant reduction (P jaw fractures should not be removed on a prophylactic basis and should be followed up clinically and radiographically to determine any treatment needs. © 2016 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

  6. Teeth size reduction in the prehistoric populations in Serbia

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    Pajević Tina

    2012-01-01

    Full Text Available Introduction. Anthropological studies show craniofacial changes with a reduction in teeth size during evolution of the human population. Objective. The objective was to measure and compare the sizes of teeth in the population of the Mesolithic-Neolithic sites in the Iron Gate Gorge and the population from the Early Bronze Age site of Mokrin. Methods. The study included teeth without advanced wear near the pulp. The material was divided according to the site of the skeletal population in two groups. Group 1 comprised 107 teeth from the Mesolithic-Neolithic sites Lepenski Vir and Vlasac. Group 2 included 158 teeth from the Mokrin graveyard dated in the Early Bronze Age. The mesio-distal diameter was measured in all teeth, while the vestibulo-oral diameter was measured in the molars only. Using the two-factor analysis of variance, the influence of sex, site and their interaction on the size of the teeth were investigated. Results. The vestibulo-oral diameter of the upper third molar was significantly higher in males compared to females. The comparison between the groups showed that the vestibulooral diameter of the lower first molar was significantly higher in group 1. Conclusion. The present difference in teeth size indicates the existence of reduction during the prehistoric times. However, the time period between the populations studied is probably too short to be manifested on a large number of teeth.

  7. Supernumerary teeth: Review of literature and decision support system

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    Deepti Amarlal

    2013-01-01

    Full Text Available Supernumerary teeth are those which are additional or in excess of the normal number. They can be either single or multiple, unilateral or bilateral and can be present anywhere in the dental arch with predilection for the premaxilla. Supernumerary teeth are mostly classified on position and form. Timing of surgical intervention of supernumerary teeth has been controversial with various authors having different opinions. Hence a new decision support system is put forward which can help in the treatment planning of supernumerary teeth.

  8. Factors influencing trace element composition in human teeth

    Energy Technology Data Exchange (ETDEWEB)

    Tandon, L. [Los Alamos National Lab., NM (United States); Iyengar, G.V. [Biomineral Sciences International, Inc., Bethesda, MD (United States)

    1997-12-01

    The authors recently compiled and reviewed the literature published in or after 1978 for 45 major, minor, and trace elements in human teeth as a part of an International Atomic Energy Agency (IAEA) study. The purpose of this paper is to discuss the various factors that influence the concentration levels of certain trace elements in human teeth. The sampling practices and analytical techniques that are applicable for trace element analysis are also discussed. It is also our intention to identify reference range of values, where data permit such conclusions. The scrutiny was designed to identify only the healthy permanent teeth, and values from teeth with fillings, caries, or periodontal diseases were eliminated.

  9. Soft dentin results in unique flexible teeth in scraping catfishes.

    Science.gov (United States)

    Geerinckx, Tom; Huysseune, Ann; Boone, Matthieu; Claeys, Myriam; Couvreur, Marjolein; De Kegel, Barbara; Mast, Peter; Van Hoorebeke, Luc; Verbeken, Kim; Adriaens, Dominique

    2012-01-01

    Teeth are generally used for actions in which they experience mainly compressive forces acting toward the base. The ordered tooth enamel(oid) and dentin structures contribute to the high compressive strength but also to the minor shear and tensile strengths. Some vertebrates, however, use their teeth for scraping, with teeth experiencing forces directed mostly normal to their long axis. Some scraping suckermouth catfishes (Loricariidae) even appear to have flexible teeth, which have not been found in any other vertebrate taxon. Considering the mineralized nature of tooth tissues, the notion of flexible teeth seems paradoxical. We studied teeth of five species, testing and measuring tooth flexibility, and investigating tooth (micro)structure using transmission electron microscopy, staining, computed tomography scanning, and scanning electron microscopy-energy-dispersive spectrometry. We quantified the extreme bending capacity of single teeth (up to 180°) and show that reorganizations of the tooth (micro)structure and extreme hypomineralization of the dentin are adaptations preventing breaking by allowing flexibility. Tooth shape and internal structure appear to be optimized for bending in one direction, which is expected to occur frequently when feeding (scraping) under natural conditions. Not all loricariid catfishes possess flexible teeth, with the trait potentially having evolved more than once. Flexible teeth surely rank among the most extreme evolutionary novelties in known mineralized biological materials and might yield a better understanding of the processes of dentin formation and (hypo)mineralization in vertebrates, including humans.

  10. Immunohistochemical studies of the periodontal membrane in primary teeth

    DEFF Research Database (Denmark)

    Bille, Marie-Louise Bastholm; Nolting, Dorrit; Kjær, Inger

    2009-01-01

    Objectives. To describe the periodontal membrane of human primary teeth immunohistochemically, while focusing on the epithelial layer of Malassez, fibers, and peripheral nerves, and to compare the findings with those of a previous study of human permanent teeth. Material and methods. Nineteen human...... could be identical to those in regions with no resorption. Conclusion. In regions without resorption, spatial organization of the periodontal membrane of primary teeth was similar to that of permanent teeth, although the number and distribution of epithelial cells and fibers differed. In regions...

  11. Triplication of deciduous teeth: A rare dental anomaly

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    Suresh Yadav

    2013-01-01

    Full Text Available Fusion of teeth is the union of two or more tooth germs, which are usually separated. Depending upon the stage of odontogenesis, it can be complete or incomplete. The present case describes fusion between the maxillary primary right central and lateral incisor with a supernumerary tooth. Clinical and radiographic examination revealed the presence of fused triple teeth. The fused teeth were extracted, sectioned and were visualized under stereomicroscope at three levels and the diagnosis of fusion of three teeth was confirmed histologically.

  12. Co-localization of histamine and norepinephrine in sympathetic ganglia and exocytosis of endogenous histamine from cardiac sympathetic nerve endings of macaca mulatto monkey

    Institute of Scientific and Technical Information of China (English)

    Ming-kaiLI; Xiao-xingLUO; Liang-weiCHEN; ZhongCHEN; JiaMENG; JingHU; Yu-meiWU; Jing-ruMENG; ZhengHOU; XueMA

    2005-01-01

    AIM To provide the evidence about localization, biosynthesis, metabolism and release of histamine from the cardiac sympathetic nerve terminals, and endogenous sympathetic histamine could inhibit itsel frelease from the nerve terminal through the presynaptic histamine H3 receptor. METHODS Using double-labeled immunohistochemistry to observe the co-localization of histamine and NE in the superior cer-vical ganglia (SCG) of macaca mulatto monkey; Different-speed centrifugation to obtain the cardiac sympathetic nerve terminal model (the cardiac synaptosomes), spectrofluorometer and ELISA techniques to detect the release of histamine from the cardiacsynaptosomes. RESULTS ( 1 ) The coexistence of histamine and norepinephrine immunoreactivities was identified in the same neuron within SCG of macaca mulatto monkey. (2) Depolarization of macaca mulatto monkey cardiac synaptosomes with 50 mmol/L potassium caused the release of endogenous histamine,

  13. The gothic arch tracing and the upper canine teeth as guides in the positioning of upper posterior teeth.

    Science.gov (United States)

    el-Gheriani, A S; Davies, A L; Winstanley, R B

    1989-09-01

    The relationship between the position of the buccal cusps of the natural upper posterior teeth and the distance between the lateral arms of the Gothic arch tracing or the distance between the upper canine teeth has been found to be constant to within +/- 2 mm. This may be of value when setting up artificial teeth for denture patients, enabling them to be positioned close to the natural predecessors.

  14. COMPARISON OF BOND STRENGTH OF THREE DENTURE TEETH MADE IN IRAN WITH RESIN BASES AND IVOCLAR DENTURE TEETH

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    R MOSHARRAF

    2002-09-01

    Full Text Available Introduction. One of the most common repairs in removable prostheses is, substitution debonded teeth in their places. In the other hand, with the incrased use of implants & the commensurate increase in force applied to prosthetic components, it is probable that tooth debonding will become an even greater clinical problem. Therefore in this study we are trying to select the strongest bond strength of Iranian denture teeth with respect to lvoclar denture teeth (Approved and recommended by ADA. Methods. In this study the upper anterior set of three Iranian denture teeth (called Berelian, Marjan and Supernevoclar and lvoclar denture teeth were used. of each type of denture teeth, 21 specimens was selected and the denture teeth glaze was removed in each specimen. Then the laboratory procedures (removal of wax & resin packing according to British Standard 3990 (BS 3990 or ISO 3336 was done. Each specimen was tested by an Instron machine. The tensile test used with the cross-head speed of 5mm/min until fracture occured. Results. The mean bond strength in Berelian teeth uppermost, afterward Marjan, Ivoclar and Super nevoclared in second, third and fourh rank respectively. But statistical analysis showed no significanrt difference among the mean bond strength in four groups of denture teeth. The percentage of cohesive fracture (sum of acrylic farcture and dental fracture in Berelian specimens was uppermost, afterward Supernevoclar and Marjan were placed in second, third & fourth rank respectively. But statistical analysis showed no significant difference among the percentage of cohesive fracture in different groups of denture teeth. Discussion. The bond strength and the percentage of cohesive fracture of Iranian denture teeth is the same & competitive to lvoclar denture teeth (approved and recommended by ADA.

  15. Efficacy of antibiotic-impregnated polymethylmethacrylate beads in a rhesus macaque (Macaca mulatta) with osteomyelitis.

    Science.gov (United States)

    Kelly, Kristi R; Kapatkin, Amy R; Zwingenberger, Allison L; Christe, Kari L

    2012-08-01

    Here we describe the successful surgical implementation of antibiotic-impregnated polymethylmethacrylate beads in a rhesus macaque (Macaca mulatta) with marked osteomyelitis. The macaque presented to the veterinary clinic with grossly contaminated bite wounds in the left ankle secondary to conspecific trauma. Radiographic findings were highly suggestive of osteomyelitis. Additional differential diagnoses included bony infarct, fracture, and cellulitis. In light of the location of the lesion and extensive tissue trauma, the animal had a poor prognosis. Systemic, broad-spectrum antibiotics were instituted. After 2 wk of care, lesions did not respond to empirical therapies. On consultation, a veterinary orthopedic surgeon at another facility recommended placement of antibiotic-impregnated polymethylmethacrylate beads at the sites of osteomyelitis. The animal underwent minor surgery in which beads were introduced into the wound. The monkey had a positive response to therapy. The animal regained full function and was returned to outdoor social housing. Veterinarians are encouraged to consider using antibiotic-impregnated polymethylmethacrylate beads when treating osteomyelitis in other nonhuman primates and in other traditional laboratory animal species.

  16. Troop Takeover and Reproductive Success of Wild Male Japanese Macaques on Yakushima Island (Macaca fuscata yakui

    Directory of Open Access Journals (Sweden)

    Sachiko Hayakawa

    2011-01-01

    Full Text Available Troop takeover is common in one-male primate groups, but there are few reports in multimale groups. Japanese macaques (Macaca fuscata form multimale groups and males commonly join troops at the bottom rank. On Yakushima island, however, where group size is relatively small, entrance into groups at the alpha position is also observed. This paper reports on the general features of troop takeover, on the predictors of takeover events, and on the reproductive success of takeover males. Troop takeovers occurred only in the mating season; nontroop males (NTMs did not cooperate with each other; former alpha males were rarely expelled from the troop; new alpha males did not commit infanticide; new alpha male tenure in the group was usually less than two years. Logistic regression analysis showed that the number of NTMs associating with a troop predicted the occurrence of troop takeover. Paternity discrimination revealed that 33.3% (3/9 of takeover males succeeded in siring offspring. Contrary to this low success rate, binary logistic regression analysis revealed that the takeover males can expect higher reproductive success compared to troop males. Entering a troop and out-competing the alpha male is one of many available strategies to attain reproductive success in male Japanese macaques.

  17. Male mate choice in Tibetan macaques Macaca thibetana at Mt. Huangshan, China

    Directory of Open Access Journals (Sweden)

    Min ZHANG, Jinhua LI, Yong ZHU, Xi WANG, Su WANG

    2010-04-01

    Full Text Available Though females are generally more selective in mate choice, males may also benefit from mate choice if male reproductive success is limited by factors other than simply the number of female mates, and if females differ in short-term reproductive potential. We studied male mate choice in a free-ranging troop of Tibetan macaques Macaca thibetana at Mt. Huangshan, China, from August 2007 to April 2008. We employed focal animal sampling and all occurrence sampling to record sexual related behaviors. Eight adult females were divided into three female quality categories according to the females’ age, rank and parity. Using male mating effort as a proxy for male mate choice, we found that males do distinguish female quality and show time-variant mating strategies. Specifically, females with dominant rank, high fecundity, and middle age attracted significantly more males. Our results suggest that female short-term reproductive potential appears to be an important variable in determining male mating effort. Male Tibetan macaques do exercise mate choice for higher quality females as well as reduce useless reproductive cost, which is consistent with the direct benefits theory of mate choice [Current Zoology 56 (2: 213–221, 2010].

  18. Gene expression profiling in the Cynomolgus macaque Macaca fascicularis shows variation within the normal birth range

    Directory of Open Access Journals (Sweden)

    Vickers Mark H

    2011-10-01

    Full Text Available Abstract Background Although an adverse early-life environment has been linked to an increased risk of developing the metabolic syndrome, the molecular mechanisms underlying altered disease susceptibility as well as their relevance to humans are largely unknown. Importantly, emerging evidence suggests that these effects operate within the normal range of birth weights and involve mechanisms of developmental palsticity rather than pathology. Method To explore this further, we utilised a non-human primate model Macaca fascicularis (Cynomolgus macaque which shares with humans the same progressive history of the metabolic syndrome. Using microarray we compared tissues from neonates in the average birth weight (50-75th centile to those of lower birth weight (5-25th centile and studied the effect of different growth trajectories within the normal range on gene expression levels in the umbilical cord, neonatal liver and skeletal muscle. Results We identified 1973 genes which were differentially expressed in the three tissue types between average and low birth weight animals (P Conclusion These differences in gene expression levels between animals in the upper and lower percentiles of the normal birth weight range may point towards early life metabolic adaptations that in later life result in differences in disease risk.

  19. Infeksi Cacing Saluran Pencernaan Monyet Ekor Panjang (Macaca fascicularis Yang Diperdagangkan Di Pasar Satria Denpasar

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    Kadek Ari Dwipayanti

    2014-02-01

    Full Text Available Penelitian ini bertujuan untuk mengetahui jenis dan intensitas serta prevalensi infeksi cacing saluran pencernaan pada monyet ekor panjang (Macaca fascicularis yang diperdagangkan di Pasar Satria Denpasar. Empat puluh lima sampel feses M. fascicularis (24 ekor monyet betina dan 21 ekor monyet jantan diambil secara aseptis, diberi label dan selanjutnya diperiksa di laboratorium Parasitologi FKH Universitas Udayana. Sampel diperiksa menggunakan metode konsentrasi sedimentasi untuk mengidentifikasi jenis cacing dan modifikasi McMaster untuk mengetahui intensitas infeksi. Jenis cacing saluran pencernaan yang berhasil diidentifikasi berturut-turut adalah Ancylostoma sp. (91,1%, Trichostrongylus sp./Oesophagostonum sp. (73,3%, Trichuris sp. (22,2%, Ascaris sp. dan Taenia sp. (4,4%. Rataan intensitas infeksi cacing      Ancylostoma sp. 4913 ± 4849 telur per gram tinja, Thrichostrongylus sp./ Oesophagostonum sp. 871 ± 816 telur per gram tinja, Trichuris sp. berkisar      171 ± 111 telur per gram tinja. Ascaris sp. dan Taenia sp. memiliki intensitas terendah yakni <100 telur per gram tinja. Secara umum prevalensi kecacingan adalah 93,3%. Prevalensi kecacingan pada monyet betina (52,2% sedangkan pada monyet jantan (48,8%. Berdasarkan umur, prevalensi kecacingan pada anakan, bayi, dan dewasa berturut-turut (72,1%, (25,6%, dan (2,3%. Pola infeksi umumnya tipe infeksi campuran (82,3% dibandingkan infeksi tunggal (17,7%.

  20. Nutritional Composition of Fruits Selected by Long-Tailed Macaques (Macaca fascicularis) in Kuala Selangor, Malaysia.

    Science.gov (United States)

    Kassim, Norazila; Hambali, Kamarul; Amir, Aainaa

    2017-01-01

    Proximate analysis of twelve species of fruits commonly consumed by long-tailed macaques (Macaca fascicularis), i.e., Arenga pinnata, Areca catechu, Terminalia catappa, Elaeis guineensis, Lagerstroemia tomentosa, Mangifera indica, Cascabela thevetia, Muntingia calabura, Musa sp., Artocarpus heterophyllus, Ficus tinctoria ssp. gibbosa and Ficus microcarpa, was conducted with the specific objective to determine the nutritional composition of the foodstuffs of long-tailed macaques. The results showed the following order of nutrients: fibre, protein, fat and ash. Based on the results of the chemical analysis, the highest percentage of fibre content (52.7%), protein (9.9%), fat (77.2%) and ash (8.5%) were found in A. catechu, T. catappa, E. guineensis and C. thevetia, respectively. The nutrient composition of these twelve fruit species was found to differ (ANOVA test: crude protein, F (11,24) = 87.978, p < 0.05; crude fibre, F (11,24) = 28.886, p < 0.05; crude fat, F (11,24) = 2081.396, p < 0.05 and ash, F (11,24) = 41.011, p < 0.05). Fibre was found in the highest amount among the four types of nutrients studied. Here, A. catechu had the highest relative fibre content of all tested fruits, E. guineensis had the highest fat content, T. catappa had the highest protein content, and the total mineral content was highest in C. thevetia.

  1. Development of an integrative database with 499 novel microsatellite markers for Macaca fascicularis

    Directory of Open Access Journals (Sweden)

    Higashino Atsunori

    2009-06-01

    Full Text Available Abstract Background Cynomolgus macaques (Macaca fascicularis are a valuable resource for linkage studies of genetic disorders, but their microsatellite markers are not sufficient. In genetic studies, a prerequisite for mapping genes is development of a genome-wide set of microsatellite markers in target organisms. A whole genome sequence and its annotation also facilitate identification of markers for causative mutations. The aim of this study is to establish hundreds of microsatellite markers and to develop an integrative cynomolgus macaque genome database with a variety of datasets including marker and gene information that will be useful for further genetic analyses in this species. Results We investigated the level of polymorphisms in cynomolgus monkeys for 671 microsatellite markers that are covered by our established Bacterial Artificial Chromosome (BAC clones. Four hundred and ninety-nine (74.4% of the markers were found to be polymorphic using standard PCR analysis. The average number of alleles and average expected heterozygosity at these polymorphic loci in ten cynomolgus macaques were 8.20 and 0.75, respectively. Conclusion BAC clones and novel microsatellite markers were assigned to the rhesus genome sequence and linked with our cynomolgus macaque cDNA database (QFbase. Our novel microsatellite marker set and genomic database will be valuable integrative resources in analyzing genetic disorders in cynomolgus macaques.

  2. Allele frequency of antiretroviral host factor TRIMCyp in wild-caught cynomolgus macaques (Macaca fascicularis)

    Science.gov (United States)

    Saito, Akatsuki; Kawamoto, Yoshi; Higashino, Atsunori; Yoshida, Tomoyuki; Ikoma, Tomoko; Suzaki, Yuriko; Ami, Yasushi; Shioda, Tatsuo; Nakayama, Emi E.; Akari, Hirofumi

    2012-01-01

    A recent study showed that the frequency of an antiretroviral factor TRIM5 gene-derived isoform, TRIMCyp, in cynomolgus macaques (Macaca fascicularis) varies widely according to the particular habitat examined. However, whether the findings actually reflect the prevalence of TRIMCyp in wild cynomolgus macaques is still uncertain because the previous data were obtained with captive monkeys in breeding and rearing facilities. Here, we characterized the TRIM5 gene in cynomolgus macaques captured in the wild, and found that the frequency of the TRIMCyp allele was comparable to those in captive monkeys. This suggests that the previous results with captive monkeys do indeed reflect the natural allele frequency and that breeding and rearing facilities may not affect the frequency of TRIM5 alleles. Interestingly, the prevalence of a minor haplotype of TRIMCyp in wild macaques from the Philippines was significantly lower than in captive ones, suggesting that it is advantageous for wild monkeys to possess the major haplotype of TRIMCyp. Overall, our results add to our understanding of the geographic and genetic prevalence of cynomolgus macaque TRIMCyp. PMID:22969754

  3. Circulation of Campylobacter spp. in rhesus monkeys (Macaca mulatta held in captivity: a longitudinal study

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    Márcia Cristina Ribeiro Andrade

    2007-02-01

    Full Text Available Campylobacteriosis is an extremely important zoonosis, circulating freely in the environment. In nonhuman primates kept in open facilities and bred for experimental purposes, the presence of Campylobacter spp. could cause severe damage to the production and interfere with the results of scientific research. In this paper, we assessed the circulation of Campylobacter spp. in a colony of clinically healthy rhesus monkeys (Macaca mulatta destined to research. The analysis was carried out during seven non-consecutive years. Data showed that despite several changes made in animal management along the studied years in order to control this zoonosis, reduction of bacterial charge did not occur. Significant differences among the age groups and sex were observed. Infants showed higher susceptibility than adult animals. In general males were more infected than females. Modifications adopted in the handling techniques need to be reviewed with the intent of improving the production, reducing bacterial infection of the stock and avoiding undesirable cross reactions in the research carried out with these animals. Therefore, this paper alerts professionals that work directly with captive rhesus monkeys about the risks of Campylobacter spp. infection and possible interference on the experimental procedures.

  4. New-Onset Diabetes Mellitus After Transplantation in a Cynomolgus Macaque (Macaca fasicularis).

    Science.gov (United States)

    Matthews, Kristin A; Tonsho, Makoto; Madsen, Joren C

    2015-08-01

    A 5.5-y-old intact male cynomolgus macaque (Macaca fasicularis) presented with inappetence and weight loss 57 d after heterotopic heart and thymus transplantation while receiving an immunosuppressant regimen consisting of tacrolimus, mycophenolate mofetil, and methylprednisolone to prevent graft rejection. A serum chemistry panel, a glycated hemoglobin test, and urinalysis performed at presentation revealed elevated blood glucose and glycated hemoglobin (HbA1c) levels (727 mg/dL and 10.1%, respectively), glucosuria, and ketonuria. Diabetes mellitus was diagnosed, and insulin therapy was initiated immediately. The macaque was weaned off the immunosuppressive therapy as his clinical condition improved and stabilized. Approximately 74 d after discontinuation of the immunosuppressants, the blood glucose normalized, and the insulin therapy was stopped. The animal's blood glucose and HbA1c values have remained within normal limits since this time. We suspect that our macaque experienced new-onset diabetes mellitus after transplantation, a condition that is commonly observed in human transplant patients but not well described in NHP. To our knowledge, this report represents the first documented case of new-onset diabetes mellitus after transplantation in a cynomolgus macaque.

  5. Training pair-housed Rhesus macaques (Macaca mulatta) using a combination of negative and positive reinforcement.

    Science.gov (United States)

    Wergård, Eva-Marie; Temrin, Hans; Forkman, Björn; Spångberg, Mats; Fredlund, Hélène; Westlund, Karolina

    2015-04-01

    When training animals, time is sometimes a limiting factor hampering the use of positive reinforcement training (PRT) exclusively. The aim of this study was to evaluate the effects of a combination of negative and positive reinforcement training (NPRT). Twenty naïve female Rhesus macaques (Macaca mulatta) were trained in 30 sessions with either PRT (n=8) or NPRT (n=12) to respond to a signal, move into a selected cage section and accept confinement. In the NPRT-group a signal preceded the presentation of one or several novel, and thus aversive, stimuli. When the correct behaviour was performed, the novel stimulus was removed and treats were given. As the animal learned to perform the correct behaviour, the use of novel stimuli was decreased and finally phased out completely. None of the PRT-trained animals finished the task. Ten out of 12 monkeys in the NPRT-group succeeded to perform the task within the 30 training sessions, a significant difference from the PRT-group (p=0.0007). A modified approach test showed no significant difference between the groups (p=0.67) in how they reacted to the trainer. The results from this study suggest that carefully conducted NPRT can be an alternative training method to consider, especially when under a time constraint.

  6. Facial width-to-height ratio relates to dominance style in the genus Macaca

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    Marta Borgi

    2016-03-01

    Full Text Available Background. Physical, visual, chemical, and auditory cues signalling fighting ability have independently evolved in many animal taxa as a means to resolve conflicts without escalating to physical aggression. Facial width-to-height ratio (fWHR, i.e., the relative width to height of the face has been associated with dominance-related phenotypes both in humans and in other primates. In humans, faces with a larger fWHR are perceived as more aggressive. Methods. We examined fWHR variation among 11 species of the genus Macaca. Macaques have been grouped into four distinct categories, from despotic to tolerant, based on their female dominance style. Female dominance style is related to intra- and inter-sexual competition in both males and females and is the result of different evolutionary pressure across species. We used female dominance style as a proxy of intra-/inter-sexual competition to test the occurrence of correlated evolution between competitive regimes and dominance-related phenotypes. fWHR was calculated from 145 2D photographs of male and female adult macaques. Results. We found no phylogenetic signal on the differences in fWHR across species in the two sexes. However, fWHR was greater, in females and males, in species characterised by despotic female dominance style than in tolerant species. Discussion. Our results suggest that dominance-related phenotypes are related to differences in competitive regimes and intensity of inter- and intra-sexual selection across species.

  7. Surrogate mobility and orientation affect the early neurobehavioral development of infant rhesus macaques (Macaca mulatta).

    Science.gov (United States)

    Dettmer, Amanda M; Ruggiero, Angela M; Novak, Melinda A; Meyer, Jerrold S; Suomi, Stephen J

    2008-05-01

    A biological mother's movement appears necessary for optimal development in infant monkeys. However, nursery-reared monkeys are typically provided with inanimate surrogate mothers that move very little. The purpose of this study was to evaluate the effects of a novel, highly mobile surrogate mother on motor development, exploration, and reactions to novelty. Six infant rhesus macaques (Macaca mulatta) were reared on mobile hanging surrogates (MS) and compared to six infants reared on standard stationary rocking surrogates (RS) and to 9-15 infants reared with their biological mothers (MR) for early developmental outcome. We predicted that MS infants would develop more similarly to MR infants than RS infants. In neonatal assessments conducted at Day 30, both MS and MR infants showed more highly developed motor activity than RS infants on measures of grasping (p = .009), coordination (p = .038), spontaneous crawl (p = .009), and balance (p = .003). At 2-3 months of age, both MS and MR infants displayed higher levels of exploration in the home cage than RS infants (p = .016). In a novel situation in which only MS and RS infants were tested, MS infants spent less time near their surrogates in the first five minutes of the test session than RS infants (p = .05), indicating a higher level of comfort. Collectively, these results suggest that when nursery-rearing of infant monkeys is necessary, a mobile hanging surrogate may encourage more normative development of gross motor skills and exploratory behavior and may serve as a useful alternative to stationary or rocking surrogates.

  8. Genetic diversity and population structure of long-tailed macaque (Macaca fascicularis) populations in Peninsular Malaysia.

    Science.gov (United States)

    Nikzad, Sonia; Tan, Soon Guan; Yong Seok Yien, Christina; Ng, Jillian; Alitheen, Noorjahan Banu; Khan, Razib; Rovie-Ryan, Jeffrine J; Valdiani, Alireza; Khajeaian, Parastoo; Kanthaswamy, Sree

    2014-12-01

    The genetic diversity and structure of long-tailed macaques (Macaca fascicularis) in Peninsular Malaysia, a widely used non-human primate species in biomedical research, have not been thoroughly characterized. Thirteen sites of wild populations of long-tailed macaques representing six states were sampled and analyzed with 18 STR markers. The Sunggala and Penang Island populations showed the highest genetic diversity estimates, while the Jerejak Island population was the most genetically discrete due to isolation from the mainland shelf. Concordant with pairwise F(st) estimates, STRUCTURE analyses of the seven PCA-correlated clusters revealed low to moderate differentiation among the sampling sites. No association between geographic and genetic distances exists, suggesting that the study sites, including island study sites, are genetically if not geographically contiguous. The status of the genetic structure and composition of long-tailed macaque populations require further scrutiny to develop this species as an important animal model in biomedical research. © 2014 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

  9. Toxic shock due to Streptococcus pyogenes in a rhesus monkey (Macaca mulatta).

    Science.gov (United States)

    García, Anapatricia; Paul, Katherine; Beall, Bernard; McClure, Harold

    2006-09-01

    Recent years have seen a worldwide resurgence in serious infections caused by group A streptococci. This group includes Streptococcus pyogenes, one of the most common pathogens among children which causes diverse suppurative infections, such as pharyngitis, as well as nonsuppurative infections with sequelae, such as rheumatoid fever and rheumatic heart disease. S. pyogenes produces several superantigen-like erythrogenic toxins, which are believed to be associated with pyrogenicity, erythromatous skin reactions, and various immunologic and cytotoxic effects. These toxins also can cause myocardial necrosis. In addition, recently reported streptococcal infections in obstetric human patients appear to be clinically different from classic puerperal sepsis. Here, we report a case of spontaneous streptococcal infection in a pregnant female rhesus monkey (Macaca mulatta). In addition to lesions consistent with bacteremia and toxic shock, this animal had severe cardiac lesions resembling those described in humans with rheumatic heart disease. S. pyogenes was isolated from intracardiac blood, liver, placenta, and fetal tissues. This isolate also had a unique M protein gene.

  10. Exploring the components, asymmetry and distribution of relationship quality in wild Barbary macaques (Macaca sylvanus.

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    Richard McFarland

    Full Text Available Social relationships between group members are a key feature of many animal societies. The quality of social relationships has been described by three main components: value, compatibility and security, based on the benefits, tenure and stability of social exchanges. We aimed to analyse whether this three component structure could be used to describe the quality of social relationships in wild Barbary macaques (Macaca sylvanus. Moreover, we examined whether relationship quality was affected by the sex, age and rank differences between social partners, and investigated the asymmetric nature of social relationships. We collected over 1,900 hours of focal data on seven behavioural variables measuring relationship quality, and used principal component analysis to investigate how these variables clustered together. We found that relationship quality in wild Barbary macaques can be described by a three component structure that represents the value, compatibility and security of a relationship. Female-female dyads had more valuable relationships and same-age dyads more compatible relationships than any other dyad. Rank difference had no effect on the quality of a social relationship. Finally, we found a high degree of asymmetry in how members of a dyad exchange social behaviour. We argue that the asymmetry of social relationships should be taken into account when exploring the pattern and function of social behaviour in animal societies.

  11. Diet of the Assamese macaque Macaca assamensis in lime-stone habitats of Nonggang, China

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    Qihai ZHOU, Hua WEI, Zhonghao HUANG, Chengming HUANG

    2011-02-01

    Full Text Available To enhance our understanding of dietary adaptations in macaques we studied the diet of the Assamese macaque Macaca assamensis in limestone seasonal rain forests at Nonggang Nature Reserve, China from September 2005 to August 2006. Our results show that although macaques fed on many plant species, 85.2% of the diet came from only 12 species, of which a bamboo species, Indocalamus calcicolus contributed to 62% of the diet. Young leaves were staple food items (74.1% of the diet for Assamese macaques at Nonggang, and constituted the bulk of monthly diets almost year-round, ranging from 44.9% (July to 92.9% (May. Young parts of Indocalamus calcicolus unexpanded leaves contributed to a large proportion of the young leaf diet in most months. Fruit accounted for only 17.4% of the diet, with a peak of consumption in July. We suggest that this highly folivorous diet may be related to the long lean season of fruit availability in limestone habitats as well as the utilization of cliffs of low fruit availability [Current Zoology 57 (1: 18–25, 2011].

  12. Body signals during social play in free-ranging rhesus macaques (Macaca mulatta): A systematic analysis.

    Science.gov (United States)

    Yanagi, Akie; Berman, Carol M

    2014-02-01

    Social play involves one of the most sophisticated types of communication, that is, the use of play signals. Most primate research on play signals has focused on the use of the play face. However, some species appear to exhibit a variety of play signals. For example, rhesus monkeys (Macaca mulatta) have been reported to use body movements or postures that might have signal value during social play, in addition to the play face. However, it is not clear whether these body signals actually meet several criteria necessary to label them as "play signals." Here we examine the forms and possible functions of seven candidate signals that we observed exclusively during social play contexts among free-ranging rhesus monkeys on Cayo Santiago. We aim to (1) distinguish them from actual play behavior (play involving contact or chasing) using loglinear analysis and (2) determine whether they predict playful behavior using modified PC-MC methods. Two candidate signals did not resemble any behaviors used in actual play. The other five signals contained elements that lasted longer or increased their conspicuousness over similar play behaviors, suggesting ritualized characteristics. Youngsters were likely to initiate contact or chasing play significantly sooner after candidate signals than in their absence. Thus, these candidate signals appear to meet critical criteria of signals that promote, moderate or facilitate play. As such, these findings open the door to questions about why multiple play signals have evolved. © 2013 Wiley Periodicals, Inc.

  13. A non-invasive study of alopecia in Japanese macaques Macaca fuscata

    Institute of Scientific and Technical Information of China (English)

    Peng ZHANG

    2011-01-01

    This article provides information on the phenomenon of alopecia in Japanese macaques, Macaca fuscata, in various environments and proposes a 3-step scoring system for a quantitative assessment of hair loss. Results suggest that alopecia is commonly observed in Japanese macaques, with 20.5% of individuals showing head alopecia and 4.7% showing back alopecia across eight study groups. Alopecia was more commonly observed in adult females (30.8% individuals showing head alopecia and 15.3% showing back alopecia) than in other age-sex classes. Seasonal variation of back alopecia was noted, in particular, individuals with patchy back hair were more frequently observed in winter than in summer. Seasonal variation was not observed in head hair. The distribution of alopecia was also different among study groups. The wild population generally had better hair condition than provisioned populations and captive populations. The present study used a non-invasive alopecia scoring system which can be a useful, rapid and non-invasive tool to monitor animal health and well-being at a population level.

  14. Positive reinforcement training as enrichment for singly housed rhesus macaques (Macaca mulatta).

    Science.gov (United States)

    Baker, K C; Bloomsmith, M A; Neu, K; Griffis, C; Maloney, M

    2010-08-01

    Positive reinforcement training is one component of behavioural management employed to improve psychological well-being. There has been regulatory promotion to compensate for restricted social housing in part by providing human interaction to singly caged primates, implying an efficacy standard for evaluating human interaction. The effect of positive reinforcement training on the behaviour of 61 singly housed laboratory rhesus macaques (Macaca mulatta) was evaluated at two large primate facilities. Training involved body part presentation and basic control behaviours. Baseline data were compared to two treatment phases presented in varying order across individuals, six minutes per week of positive reinforcement training and six minutes per week of unstructured human interaction. While a MANOVA involving behavioural categories and study conditions across study subjects was significant, univariate ANOVAs found no effect of phase within any behavioural category. Categorising subjects according to rearing, housing facility, or baseline levels of abnormal behaviour did not reveal changes in behaviour with positive reinforcement training or human interaction. This study failed to detect, to any degree, the types of behavioural changes documented in the scientific literature to result from pairing singly housed monkeys. Implementing short durations of positive reinforcement training across large numbers of singly housed animals may not be the most effective manner for incorporating positive reinforcement training in the behavioural management of laboratory macaques. Rather, directing efforts toward individuals with specific behavioural, management, clinical, research or therapeutic needs may represent a more fruitful approach to improving psychological well-being with this technique.

  15. Buton macaques (Macaca ochreata brunnescens): crops, conflict, and behavior on farms.

    Science.gov (United States)

    Priston, Nancy E C; Wyper, Rebecca M; Lee, Phyllis C

    2012-01-01

    One consequence of anthropogenic habitat alteration is that many nonhuman primates are forced into conflict interactions with humans and their livelihood activities, especially through crop raiding. These problems are particularly acute for the endemic and threatened Buton Island macaque (Macaca ochreata brunnescens), in southeast Sulawesi, Indonesia. Our study investigated the crop raiding behavior of this species over time. Foods eaten and the behavioral repertoire exhibited by macaques during crop raiding at and inside farm perimeters were observed over a period of 8 years (2002-2009). Storage organ crops (e.g. sweet potato) were abundant and most frequently raided by macaques. Individual macaques were most commonly observed to raid close (0-10 m) to farm perimeters. Activities such as feeding, resting, moving, and social interaction varied significantly as a function of penetration distance into the farm, but only marginally between age-sex classes. The annual average raid frequency per farm decreased over the latter years of the study period, raising questions about changes in macaque foraging and ranging behavior over time and their response to farm management and mitigation strategies.

  16. Blood genomic profiles of exposures to Venezuelan equine encephalitis in Cynomolgus macaques (Macaca fascicularis

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    Hammamieh Rasha

    2007-08-01

    Full Text Available Abstract Background Lymphocytes provide invaluable whistle blowers of changes due to infections. We use the information registered by these cells using their mRNAs as they encounter the pathogen to develop patterns of expression that correspond to that specific pathogen. Venezuelan equine encephalitis (VEE is a mosquito-borne viral disease characterized by fever and one or more of the following: severe headache, back pain, myalgias, prostration, chills, nausea, vomiting, weakness and other flu-like symptoms. Screening for host mRNA obtained from blood samples after exposure to VEEV may provide the means for early detection of surrogate markers of the impending illness and provide appropriate strategies for treatment. Results We have been carrying out gene expression analysis of PBMC exposed to VEEV to extract signatures and diagnostic markers of early exposure to be used in non invasive blood analysis methods. In this study, we used high throughput gene expression analysis to identify markers of early and late exposures to VEEV in vivo in Cynomolgus macaques (Macaca fascicularis. We carried out cDNA microarrays and real time PCR on blood samples obtained from the NHP model resulting in a panel of host genes that are altered in response to VEEV. Conclusion Screening for host mRNA obtained from blood samples after exposure to VEEV may provide the means for early detection of surrogate markers of the impending illness and provide appropriate strategies for treatment.

  17. Nutritional Composition of Fruits Selected by Long-Tailed Macaques (Macaca fascicularis) in Kuala Selangor, Malaysia

    Science.gov (United States)

    Kassim, Norazila; Hambali, Kamarul; Amir, Aainaa

    2017-01-01

    Proximate analysis of twelve species of fruits commonly consumed by long-tailed macaques (Macaca fascicularis), i.e., Arenga pinnata, Areca catechu, Terminalia catappa, Elaeis guineensis, Lagerstroemia tomentosa, Mangifera indica, Cascabela thevetia, Muntingia calabura, Musa sp., Artocarpus heterophyllus, Ficus tinctoria ssp. gibbosa and Ficus microcarpa, was conducted with the specific objective to determine the nutritional composition of the foodstuffs of long-tailed macaques. The results showed the following order of nutrients: fibre, protein, fat and ash. Based on the results of the chemical analysis, the highest percentage of fibre content (52.7%), protein (9.9%), fat (77.2%) and ash (8.5%) were found in A. catechu, T. catappa, E. guineensis and C. thevetia, respectively. The nutrient composition of these twelve fruit species was found to differ (ANOVA test: crude protein, F (11,24) = 87.978, p < 0.05; crude fibre, F (11,24) = 28.886, p < 0.05; crude fat, F (11,24) = 2081.396, p < 0.05 and ash, F (11,24) = 41.011, p < 0.05). Fibre was found in the highest amount among the four types of nutrients studied. Here, A. catechu had the highest relative fibre content of all tested fruits, E. guineensis had the highest fat content, T. catappa had the highest protein content, and the total mineral content was highest in C. thevetia. PMID:28228918

  18. Japanese macaque (Macaca fuscata) mothers huddle with their young offspring instead of adult females for thermoregulation.

    Science.gov (United States)

    Ueno, Masataka; Nakamichi, Masayuki

    2016-08-01

    It is unclear whom animals select to huddle with for thermoregulation. In this study, we investigated whom Japanese macaque (Macaca fuscata) mothers huddled with-their young offspring or other adult group members-when there is need for thermoregulation. We used a focal-animal sampling method, targeting 17 females at Katsuyama, Okayama Prefecture, Japan. A majority of huddling among adult females was recorded during winter season (December, January, and February). Females who had young (0- or 1-year-old) offspring huddled less frequently with other adult females compared to females who did not have young offspring in winter. However, including young offspring, the frequency of huddling with any other individuals did not differ by whether females had young offspring. Moreover, the females who did not have young offspring huddled with other adult females more often in cloudy than in sunny weather during winter season. In contrast, females who had young offspring increased huddling with their young offspring in cloudy than in sunny weather, but did not do so with other adult females. This study indicates that Japanese macaque mothers huddle with their young offspring instead of other adult females when there is need for thermoregulation.

  19. Experimental and postexperimental effects of posteriorly directed extraoral traction in adult Macaca fascicularis.

    Science.gov (United States)

    Brandt, H C; Shapiro, P A; Kokich, V G

    1979-03-01

    The experimental, postexperimental, and postretention effects of continuous high-pull headgear force application to the maxilla were evaluated in four adult, nongrowing Macaca fascicularis monkeys. Force was applied at 450 grams per side to face-bows attached to cast maxillary splints with an implanted occipital plug for anchorage. The active experimental phase lasted from 84 days to 205 days, and its effects were documented histologically, cephalometrically, and with dry skull preparations. Postexperimental, retention, and postretention responses were documented cephalometrically. The findings of the present investigation lead to the following conclusions: 1. The termination active sutural growth is of little significance to the remodeling potential of the sutural articulations and the morphologic adaptability of the facial skeletal complex. 2. The length of time necessary for resorptive remodeling of the sutural bony projections is partially responsible for the slower rate of detectable skeletal movement in adult animals. 3. The sutural ligament in adult animals is initially less responsive to the effects of extraoral force application, possibly because of a diminished level of cellular activity at older ages. 4. Increases in age do not appear to affect the osteogenic potential of the periosteal envelope. 5. Retention aids in establishing a maintainable equilibrium following experimentally induced sutural and skeletal remodeling, but it is of little importance in maintaining the altered position of the denition. 6. The amount of postexperimental skeletal reorientation following force application to the maxilla may be related to the force level and the duration of force.

  20. Alterations in the upper facial growth of Macaca mulatta resulting from high-pull headgear.

    Science.gov (United States)

    Meldrum, R J

    1975-04-01

    Four prepubertal Macaca mulatta monkeys, ranging in age from 13 to 24 months, were used in an investigation of the effects of high-pull headgear (to a face-bow) therapy on the growth of the upper facial skeleton. Amalgam bone implants were placed across the frontomaxillary, frontozygomatic, zygomaticomaxillary, and zygomaticotemporal sutures in each animal. Three of the monkeys wore appliances consisting of a maxillary dental spling, a face-bow, two coil springs, and an acrylic helmet. The fourth monkey (control) wore only a dental splint and a face-bow. A continuous high-pull headgear force of 300 grams per side was applied to the three monkeys for 81, 87 and 89 days, respectively, before death. Procion brilliant red 8-HBS vital stain was administered to all four animals at the start of and 3 days before the end of the treatment period. The facial growth patterns were determined from lateral cephalograms taken before and after treatment, from direct measurement of implant separation at the sutures, and from histologic sections of the four mentioned facial sutures.

  1. Influence of testosterone and a novel SARM on gene expression in whole blood of Macaca fascicularis.

    Science.gov (United States)

    Riedmaier, Irmgard; Tichopad, Ales; Reiter, Martina; Pfaffl, Michael W; Meyer, Heinrich H D

    2009-04-01

    Anabolic hormones, including testosterone, have been suggested as a therapy for aging-related conditions, such as osteoporosis and sarcopenia. These therapies are sometimes associated with severe androgenic side effects. A promising alternative to testosterone replacement therapy are selective androgen receptor modulators (SARMs). SARMs have the potential to mimic the desirable central and peripheral androgenic anabolic effects of testosterone without having its side effects. In this study we evaluated the effects of LGD2941, in comparison to testosterone, on mRNA expression of selected target genes in whole blood in an non-human model. The regulated genes can act as potential blood biomarker candidates in future studies with AR ligands. Cynomolgus monkeys (Macaca fascicularis) were treated either with testosterone or LGD2941 for 90 days in order to compare their effects on mRNA expression in blood. Blood samples were taken before SARM application, on day 16 and on day 90 of treatment. Gene expression of 37 candidate genes was measured using quantitative real-time RT-PCR (qRT-PCR) technology. Our study shows that both testosterone and LGD2941 influence mRNA expression of 6 selected genes out of 37 in whole blood. The apoptosis regulators CD30L, Fas, TNFR1 and TNFR2 and the interleukins IL-12B and IL-15 showed significant changes in gene expression between control and the treatment groups and represent potential biomarkers for androgen receptor ligands in whole blood.

  2. Role of vocal tract characteristics in individual discrimination by Japanese macaques (Macaca fuscata)

    Science.gov (United States)

    Furuyama, Takafumi; Kobayasi, Kohta I.; Riquimaroux, Hiroshi

    2016-01-01

    The Japanese macaque (Macaca fuscata) exhibits a species-specific communication sound called the “coo call” to locate group members and maintain within-group contact. Monkeys have been demonstrated to be capable of discriminating between individuals based only on their voices, but there is still debate regarding how the fundamental frequencies (F0) and filter properties of the vocal tract characteristics (VTC) contribute to individual discrimination in nonhuman primates. This study was performed to investigate the acoustic keys used by Japanese macaques in individual discrimination. Two animals were trained with standard Go/NoGo operant conditioning to distinguish the coo calls of two unfamiliar monkeys. The subjects were required to continue depressing a lever until the stimulus changed from one monkey to the other. The test stimuli were synthesized by combining the F0s and VTC from each individual. Both subjects released the lever when the VTC changed, whereas they did not when the F0 changed. The reaction times to the test stimuli were not significantly different from that to the training stimuli that shared the same VTC. Our data suggest that vocal tract characteristics are important for the identification of individuals by Japanese macaques. PMID:27550840

  3. Thromboelastography values from pigtail macaques ( Macaca nemestrina): effects of age and sex.

    Science.gov (United States)

    Fong, Derek L; Ha, James C; Hotchkiss, Charlotte E

    2012-01-01

    Thromboelastography is a clinical laboratory test used to assess global hemostasis. With technologic advances and the test's reemergence in human medicine, its utility in veterinary medicine is being explored. Because assays for PT, aPTT, and d-dimers require platelet-poor plasma, whereas thromboelastography is performed on whole blood, thromboelastography provides a more accurate representation of coagulation and allows the identification of hypocoagulable, hypercoagulable, and hyperfibrinolytic states. Conflicting information has been reported about the effects of age and sex on thromboelastog- raphy in humans and animals. Human studies have reported significant effects of age and sex on thromboelastography more often than have animal studies, but few publications are available about thromboelastography in the nonhuman primate and laboratory animal literature. We used a sample of 50 pigtail macaques (Macaca nemestrina) to determine whether age or sex influence thromboelastography values. Of 5 measured and 2 calculated variables produced by thromboelastography, sex had a significant effect only on the lysis-30 parameter, which also showed significant interaction between age and sex; values increased with age in male macaques but decreased with age in female macaques. In addition, we used the data to define reference intervals for thromboelastography parameters in pigtail macaques.

  4. Clinical Manifestations of pathology of temporomandibular joints and masticatory muscles in patients with teeth occlusion and teeth row disturbances

    Directory of Open Access Journals (Sweden)

    A.V. Lepilin

    2010-06-01

    Full Text Available The aim of the research is a literature review about the problem of temporomandibular joints and masticatory muscles in patients with teeth occlusion and teeth row disturbances. Teeth occlusion and teeth row disturbances are widespread pathology of maxillofacial area, that can lead to different pathology alterations of masticatory system including musculo-articular dysfunction. Some specialists consider that the key factor of pathogenesis of musculo-articular dysfunction is occlusion disturbances, by the other opinion - discoordination of muscle contraction. Thus occlusive and muscular disorders are leading in pathogenesis and clinic of musculo-articular dysfunction

  5. Teething myths among nursing mothers in a Nigerian community

    Directory of Open Access Journals (Sweden)

    Opeodu Olanrewaju Ige

    2013-01-01

    Full Text Available Background: Many symptoms had been associated with teething in children with the possibility of overlooking potentially fatal condition. Symptoms that had been associated with teething include diarrhoea, fever, vomiting and cough. The possibility that any of these symptoms could have been due to other causes call for thorough investigation of the child before concluding that it is only "teething". Objectives: The study was carried out to assess the beliefs of nursing mothers concerning symptoms that are associated with teething among children and to identify those that would seek medical treatments in case of their children having such symptoms during teething. Materials and Methods: Two hundred and ninety nursing mothers whose children had erupted at least a tooth were interviewed in the immunisation clinics of the University College Hospital and Adeoyo Maternity Teaching Hospital, both in Ibadan, Nigeria, on their beliefs and practice concerning teething in children. Results: One hundred and eighty-eight (64.8% of the mothers associated symptoms such as fever, cough, catarrh and diarrhoea with eruption of teeth in their children. Over half of the women agreed that a child having either fever (51.0%, ear infection (57.6% or cough (50.3% should be promptly taken for medical consultation and not be tagged "teething", while for other symptoms such as gum pain (74.5%, sleepless night (56.6%, vomiting (51.4% and diarrhoea (51.7%, over half of the mothers believed that the symptoms will resolve following the eruption of the teeth. Conclusion: The study demonstrated that mothers in the study attributes several symptoms to teething, which could be detrimental to the survival of their children as the symptom could have been due to other causes. There is, therefore, need for public enlightenment to create awareness on the possible effect of presumptuous belief that childhood diseases are due to teething process.

  6. Electron probe microananlysis of fluorotic bovine teeth

    Energy Technology Data Exchange (ETDEWEB)

    Shearer, T.R.; Kolstad, D.L.; Suttie, J.W.

    1978-09-01

    Incisor teeth were obtained from adult cattle which since 4 months of age to 5 or 6 years were maintained on rations containing a yearly average of 40 ppM F in the forage. Microchemical analyses were performed on the fluorotic bovine incisors. The microdistribution of fluoride varied markedly at different sites within the same tooth. Fluoride concentrations varied with depth from the tooth surface and were influenced by the concentrations of fluoride present in the forage during amelogenesis, and the presence of hypoplastic pits and hyperplastic coronal cementum in enamel. The cementum in these lesions contained remarkably high concentrations of fluoride, and it was less calcified and more porous than adjacent enamel. 5 figures.

  7. The Vikings bare their filed teeth.

    Science.gov (United States)

    Arcini, Caroline

    2005-12-01

    Finds of deliberate dental modification have for the first time been found in archaeological human skeletal material from Europe. The type of modification is a horizontally filed furrow on the frontal upper part of the tooth crown. The furrows are single or, more usually, multiple, and are found on the front teeth in the maxilla. The affected individuals are 24 men from the Viking Age (ca. 800-1050 AD), found in present day Sweden and Denmark. The marks are so well-made that it is most likely they were filed by a person of great skill. The reason for, and importance of, the furrows are obscure. The affected individuals may have belonged to a certain occupational group (such as tradesmen), or the furrows could have been pure decoration.

  8. Dental fluorosis in bovine temporary teeth

    Energy Technology Data Exchange (ETDEWEB)

    Suttie, J.W.; Clay, A.B.; Shearer, T.R.

    1985-02-01

    Deciduous incisors from calves born to dams fed an average of 40 mg of fluoride/kg of forage ration (40 ppm) were compared with incisors from calves born to dams fed a normal dairy ration. Skeletal fluoride concentration in the calves born to fluoride-fed dams was increased 5 to 8 fold, but enamel mottling and hypoplasia, typical of permanent bovine incisor dental fluorosis were not seen by gross, histologic, or radiologic examination. Decreases in the amount of enamel on the tooth or hardness of the enamel were not observed. These data do not support recent reports of widespread dental fluorosis of deciduous bovine teeth as a clinical sign of fluoride toxicity.

  9. Triplication of Deciduous Teeth: A Rare Dental Anomaly

    African Journals Online (AJOL)

    with the formation of one abnormally large tooth or incomplete, ... primary teeth can appear in several ways, usually involving two ... The treatment plan was aimed at removal of fused teeth. ... Figure 6: The apical third showing merging of root canals of the fused ... If the fusion begins before calcification, then the union will.

  10. Pulp response in sound and carious teeth: a pilot study.

    Science.gov (United States)

    Paterson, R C

    1981-02-01

    This article describes a pilot investigation in which the response of the pulps in both sound and carious rat molar teeth to traumatic exposure and treatment with three different compounds was assessed. Two of the compounds appeared to give a more favorable response in carious teeth. These results are discussed, and future experiments described.

  11. Size variation in samples of fossil and recent murid teeth

    NARCIS (Netherlands)

    Freudenthal, M.; Martín Suárez, E.

    1990-01-01

    The variability coefficient proposed by Freudenthal & Cuenca Bescós (1984) for samples of fossil cricetid teeth, is calculated for about 200 samples of fossil and recent murid teeth. The results are discussed, and compared with those obtained for the Cricetidae.

  12. Size variation in samples of fossil and recent murid teeth

    NARCIS (Netherlands)

    Freudenthal, M.; Martín Suárez, E.

    1990-01-01

    The variability coefficient proposed by Freudenthal & Cuenca Bescós (1984) for samples of fossil cricetid teeth, is calculated for about 200 samples of fossil and recent murid teeth. The results are discussed, and compared with those obtained for the Cricetidae.

  13. Patterns of bone loss around teeth restored with endodontic posts

    NARCIS (Netherlands)

    Katsamakis, S.; Timmerman, M.; van der Velden, U.; de Cleen, M.; van der Weijden, F.

    2009-01-01

    Objectives: This retrospective study described the pattern of bone loss around teeth with endodontic posts in periodontitis patients, and compared it with contra-lateral teeth without posts. Material and Methods: From full-mouth radiographic surveys of 146 periodontitis patients (35 years), 194 root

  14. ELECTRIC PULP TEST OF TEETH WITH PERIODONTAL DISEASE.

    Directory of Open Access Journals (Sweden)

    Tsonko Uzunov

    2014-10-01

    Full Text Available Purpose: The aim of the research is to investigate the change in pulp vitality of teeth with periodontal disease using electric pulp tester (EPT. Methods: Subjected to observation were 108 patients with chronic periodontitis. Vitality of 805 teeth with periodontal pocket depth greater than 4 mm was studied by EPT. The research was conducted with EPT "Yonovit ". Results: The highest percentage of surveyed teeth (68.4% respond to the norm when they are tested with EPT – values between 3 μA and 10 μA . Teeth that respond to EPT with values ​​below 3 μA and between 35-100 μA are relatively equal - respectively 4.3% and 3.3%. With increased threshold of irritation – 10-35 μA react 23.4% of teeth. Small number of teeth have threshold of irritation over 100 μA - 0.6%. Conclusion: The value of EPT among periodontal damaged teeth depends on many factors - patient's age, extent of periodontal affect, group affiliation of teeth, etc.

  15. Rare occurrence of bilaterally impacted mandibular supernumerary teeth

    Directory of Open Access Journals (Sweden)

    Vinay Kumar Bhardwaj

    2012-01-01

    Full Text Available Introduction: Supernumerary teeth are present in addition to the normal complement of teeth in permanent or deciduous dentitions. Incidence is high in permanent dentition, affects both the gender. They are more common in males, with the male to female ratio of 2:1. When the supernumerary teeth are causing problems such as, extensive resorption of adjacent teeth, hindering the eruption or malposition of permanent teeth, early surgical intervention is recommended. Case Report: A case of bilaterally impacted supernumerary premolars was reported when an orthopentomograph view was taken which revealed the presence of additional teeth impacted in relation to 35-36 and 45-46. Surgical removal was done as they were resorbing the roots of teeth in their vicinity. Discussion: Literature reports increased occurrence of the supernumeraries in the maxilla but supernumerary premolars are more likely to develop in the mandible. Etiology of supernumerary teeth is ambiguous and is due to following conditions:atavism or reversion, heredity, aberrations during embryologic formation, progress zone, and unified etiologic explanation.

  16. The effects of impacted premaxillary supernumerary teeth on permanent incisors

    Energy Technology Data Exchange (ETDEWEB)

    Jung, Yun Hoa; Kim, Ji Yeon; Cho, Bong Hae [School of Dentistry, Pusan National University, Yangsan (Korea, Republic of)

    2016-12-15

    The aim of this study was to examine the radiographic features associated with impacted premaxillary supernumerary teeth, to determine the relationship between their characteristics and their effects on permanent incisors, and to investigate the types of orthodontic treatment that patients received after the extraction of impacted supernumerary teeth. The clinical records and radiographs of 193 patients whose impacted premaxillary supernumerary teeth were removed were retrospectively reviewed, and 241 impacted supernumerary teeth were examined. Cone-beam computed tomographic images and panoramic radiographs were examined to determine the number, location, sagittal position, orientation, and morphology of the supernumerary teeth. Their effects on permanent incisors and the orthodontic treatment received by patients after the extraction of the supernumeraries were also investigated. Supernumerary teeth were most frequently observed in the central incisor region, in the palatal position, in the inverted orientation, and were most commonly conical in shape. The most common complication was median diastema, followed by displacement and delayed eruption of the adjacent incisors. Ten (71.4%) of the 14 odontomas showed delayed eruption of the adjacent incisors. Displacement of the incisors was more frequently observed in association with supernumerary teeth with tuberculate or supplemental shapes. Orthodontic traction was most frequently performed after the removal of odontomas. In 32 cases (13.3%), permanent incisors erupted after the orthodontic creation of sufficient space. Median diastema was most common complication. The delayed eruption of incisors was common in supernumerary teeth with a vertical orientation and an odontoma shape.

  17. Assessment of the periapical health of abutment teeth: A ...

    African Journals Online (AJOL)

    2014-11-29

    Nov 29, 2014 ... the preparation of teeth for fixed partial dentures. This procedure may lead to irreversible damage of the dental pulp if not carried out carefully. ... diseases of endodontic origin which affect the abutment teeth are the biological ...

  18. Bilateral hamartoma of tonsils bearing ectopic teeth: a case report

    OpenAIRE

    Barman, Debasis; Majumdar, Pallab Kumar; Majumdar, Swapan Kumar

    2003-01-01

    Ectopic teeth presenting in bath the tonsils with hatnartomatous lesion has not been reported earlier. We present here a case of benign hamartoma of both the tonsils bearing 7 teeth in a 13 year old girl and also discuss about unusual Ectopic sites of tooth eruption as well as benign lesions of tonsil.

  19. Surgically facilitated experimental movement of teeth : systematic review

    NARCIS (Netherlands)

    Liem, A. M. L.; Hoogeveen, E. J.; Jansma, J.; Ren, Y.

    2015-01-01

    Several surgical techniques based on corticotomy and dental distraction have been developed to improve the movement of teeth and reduce the duration of orthodontic treatment. In this systematic review we have critically assessed published studies on the experimental movement of teeth to find out whe

  20. Modified Anchor Shaped Post Core Design for Primary Anterior Teeth

    OpenAIRE

    R. Rajesh; Kusai Baroudi; K. Bala Kasi Reddy; Praveen, B. H.; V. Sumanth Kumar; Amit, S

    2014-01-01

    Restoring severely damaged primary anterior teeth is challenging to pedodontist. Many materials are tried as a post core but each one of them has its own drawbacks. This a case report describing a technique to restore severely damaged primary anterior teeth with a modified anchor shaped post. This technique is not only simple and inexpensive but also produces better retention.

  1. Modified Anchor Shaped Post Core Design for Primary Anterior Teeth

    Directory of Open Access Journals (Sweden)

    R. Rajesh

    2014-01-01

    Full Text Available Restoring severely damaged primary anterior teeth is challenging to pedodontist. Many materials are tried as a post core but each one of them has its own drawbacks. This a case report describing a technique to restore severely damaged primary anterior teeth with a modified anchor shaped post. This technique is not only simple and inexpensive but also produces better retention.

  2. Modified anchor shaped post core design for primary anterior teeth.

    Science.gov (United States)

    Rajesh, R; Baroudi, Kusai; Reddy, K Bala Kasi; Praveen, B H; Kumar, V Sumanth; Amit, S

    2014-01-01

    Restoring severely damaged primary anterior teeth is challenging to pedodontist. Many materials are tried as a post core but each one of them has its own drawbacks. This a case report describing a technique to restore severely damaged primary anterior teeth with a modified anchor shaped post. This technique is not only simple and inexpensive but also produces better retention.

  3. The effects of impacted premaxillary supernumerary teeth on permanent incisors

    Science.gov (United States)

    Jung, Yun-Hoa; Kim, Ji-Yeon

    2016-01-01

    Purpose The aim of this study was to examine the radiographic features associated with impacted premaxillary supernumerary teeth, to determine the relationship between their characteristics and their effects on permanent incisors, and to investigate the types of orthodontic treatment that patients received after the extraction of impacted supernumerary teeth. Materials and Methods The clinical records and radiographs of 193 patients whose impacted premaxillary supernumerary teeth were removed were retrospectively reviewed, and 241 impacted supernumerary teeth were examined. Cone-beam computed tomographic images and panoramic radiographs were examined to determine the number, location, sagittal position, orientation, and morphology of the supernumerary teeth. Their effects on permanent incisors and the orthodontic treatment received by patients after the extraction of the supernumeraries were also investigated. Results Supernumerary teeth were most frequently observed in the central incisor region, in the palatal position, in the inverted orientation, and were most commonly conical in shape. The most common complication was median diastema, followed by displacement and delayed eruption of the adjacent incisors. Ten (71.4%) of the 14 odontomas showed delayed eruption of the adjacent incisors. Displacement of the incisors was more frequently observed in association with supernumerary teeth with tuberculate or supplemental shapes. Orthodontic traction was most frequently performed after the removal of odontomas. In 32 cases (13.3%), permanent incisors erupted after the orthodontic creation of sufficient space. Conclusion Median diastema was most common complication. The delayed eruption of incisors was common in supernumerary teeth with a vertical orientation and an odontoma shape. PMID:28035303

  4. Bonding of acrylic denture teeth to resin denture bases.

    Science.gov (United States)

    Geerts, G A V M; Stuhlinger, M E

    2012-07-01

    Anterior teeth debonding from dentures is a common problem. This study tested the bond strength of denture teeth to two types of denture resin, with and without grooving the ridge-lap surface. Bond strength and fracture type of three different groups were compared: 1. Teeth bonded to heat-cured polymethyl methacrylate (PMMA); 2. Teeth bonded to pour-type PMMA; 3. Grooved teeth bonded to pour-type PMMA. Specimens were manufactured following ISO standard 22112. Force values at failure were analysed using one-way analysis of variance, using the mixed procedure with confidence interval of 95%. Types of failure were identified as adhesive, cohesive or combination. In descending order, mean failure forces were 418.55N (Group One), 367.55N (Group Two) and 290.05N (Group Three). There was no significant difference between the means of groups 1 and 2 (p = 0.0627). Group Three differed from both other groups (p denture teeth (83% and 72% respectively); group Three showed predominantly cohesive fractures within the denture PMMA (75%). Without ridge-lap modification, the bond strengths of denture teeth to pour-type and heat-cured denture resin were similar. Failures were predominantly of cohesive nature within the teeth themselves. Grooving the ridge-lap reduced fracture resistance and led to breakages predominantly in denture PMMA.

  5. Facial lesions in piglets with intact or grinded teeth

    Directory of Open Access Journals (Sweden)

    Hansson Monica

    2012-04-01

    Full Text Available Abstract Background Piglets are born with eight sharp teeth that during nursing can cause facial lesions on littermates and teat lesions on the sow. Teeth grinding in piglets is therefore often practiced to reduce these lesions. The aim of this study was to assess the consequences of grinding piglet teeth in regard to the occurrence of lesions. In this study the piglets' teeth were grinded in 28 litters, and in 36 litters the piglets' teeth were kept intact. Twice, one time during the first week and one time during the second week after birth facial lesions of the piglets were scored and the teats of the sows were examined for lesions. The facial lesion score accounted for the amount and severity of lesions. The individual observations on piglets in the litter were synthesized in a litter facial lesion score. Findings 69.8% and 43.5% of the piglets had facial lesions in week 1 and week 2 respectively. The effect of treatment was not significant on litter facial lesion score. The litter facial lesion score was higher in week 1 than in week 2 (p p = 0.003 than in small litters. Mortality between week 1 and week 2 was higher in litters with intact teeth (p = 0.02. Sow teat lesions only occurred if litters had intact teeth. Conclusions According to our results teeth grinding is only justifiable in large litters.

  6. The influence of exposure to UVβ of fluorescent light on the bone remodeling of hypoestrogenic Macaca fascicularis

    Directory of Open Access Journals (Sweden)

    I. A. Rachman

    2001-06-01

    Full Text Available The prevention of osteoporosis is a spesific problem that should be dealt with by increasing the women's lift expectation. The decrease of calcitriol and estrogen levels, which have a receptor in the osteoblast, will result in bone mineralization (due to calcitriol and the information of type 1 collagen (due to estrogen. The formation of calcitriol with the main basic materials from vitamin D3 is achieved with the aid of sunray UVβ, The changes in the lifestyle of women, which make them now accustomed to performing indoor activities and prevent them from being exposed to UVβ all day, have resulted in the decrease of vitamin D3 in calcitriol in women. In addition, when entering the menopausal age they will be threatened with early osteoporosis. The exposure to the UVβ of fluorescent light with the wave length identical to sun of 290-320 nm has long been known as a modality for treating skin diseases in the hope that the production of vitamin D3  will be increased. We exposed Macaca fascicularis, whose estrogen levels were set at normal, beginning low, beginning very low levels, to UVβ of fluorescent light. It showed that the Macaca fascicularis that were exposed to UVβ experienced an increase in osteocalcin with unchanged DPD which means that bone remodeling remains unchanged. By contrast, Macaca fascicularis with normal, beginning low, and beginning very low estrogen levels which were not exposed to UVβ were found to experience a decrease in osteocalcin and unchanged DPD levels. This means that a change has occurred in the bone remodeling toward bone resorption. (Med J Indones 2001; 10: 63-8Keywords: UVβ, osteoporosis, estrogen, vitamin D3, calcitriol, osteocalcin, DPD

  7. Forensic study of sex determination using PCR on teeth samples.

    Directory of Open Access Journals (Sweden)

    Murakami H

    2000-02-01

    Full Text Available In this study, sex determination using polymerase chain reaction (PCR on tooth material was evaluated from the viewpoint of forensic medicine. The sensitivity of PCR for detection of the Y chromosome-specific alphoid repeat sequence and the X chromosome-specific alphoid repeat sequence was 0.5 pg of genomic DNA. Sex could be determined by PCR of DNA extracted from the pulp of 16 freshly extracted permanent teeth and dentine including the surface of the pulp cavity of 6 freshly extracted milk teeth. Sex could be determined using the pulp in all 20 teeth (10 male and 10 female preserved at room temperature for 22 years. For the pulp of teeth stored in sea water, the sex could be determined in all 8 teeth immersed for 1 week and in 5 of 6 teeth immersed for 4 weeks. In the remaining 1 tooth, in which sex determination based on the pulp failed, the sex could be determined correctly when DNA extracted from the tooth hard tissue was examined. For teeth stored in soil, the sex could be determined accurately in all 8 teeth buried for 1 week, 7 of 8 teeth buried for 4 weeks, and in all 6 teeth buried for 8 weeks. When teeth were heated for 30 min, sex determination from the pulp was possible in all teeth heated to 100, 150, and 200 degrees C, and even in some teeth heated to 250 degrees C. When this method was applied to actual forensic cases, the sex of a mummified body estimated to have been discovered half a year to 1 year after death could be determined readily by examination of the dental pulp. In the skeletons of 2 bodies placed under water for approximately 1 year and approximately 11 years and 7 months, pulp tissues had been dissolved and lost, but sex determination was possible using DNA extracted from hard dental tissues. These results indicate that this method is useful in forensic practices for sex determination based on teeth samples.

  8. [Clinical anatomy of the horse: teeth and dentition].

    Science.gov (United States)

    Staszyk, C

    2015-01-01

    The routine inspection of the equine oral cavity allows a numerical assessment of the teeth and provides information about positional changes within the dentition. By use of appropriate dental equipment, the occlusal surfaces of all teeth can be inspected and diagnosed. However, neither the teeth nor their occlusal surfaces are constant structures. Instead, equine teeth and, in particular, their occlusal surfaces are subjected to continuous morphological and positional changes due to the effects of aging and the equine-specific high amount of occlusal wear. Therefore, it is mandatory to define anatomical criteria, which allow us to distinguish between anatomical variations and pathological conditions. Moreover, an unambiguous nomenclature with regard to the equine-specific dental anatomy is essential. This article provides a tutorial overview of the equine dental anatomy as well as recent findings in the field of equine dentistry. Special attention is paid to dynamic changes within both individual teeth and dentition.

  9. Strontium in 19th century Australian children's teeth

    Science.gov (United States)

    Williams, A.-M. M.; Donlon, D. A.; Bennett, C. M.; Siegele, R.

    2002-05-01

    The enamel of teeth from 57 children, who died in the mid to late 1800s, were analysed to investigate strontium (Sr) concentrations in historic teeth. Teeth were analysed using proton induced X-ray emission at the Australian Nuclear Science and Technology Organisation (ANSTO). Where available, multiple teeth were analysed for each individual including permanent (molars and premolars) and deciduous teeth (molars). Preliminary results show that Sr does not appear to be affected by the postmortem environment. Sr levels in permanent molars strongly correlate with levels in the premolars but not with the deciduous molars. Concerns are raised over the large variation seen in Sr levels and the effect it would have on the interpretation of Sr levels in studies with small sample sizes.

  10. Prognosis of teeth involved in the line of mandibular fractures.

    Science.gov (United States)

    Kahnberg, K E; Ridell, A

    1979-06-01

    The management of teeth positioned in the line of mandibular jaw fractures was studied by a follow-up examination of 132 patients with mandibular fractures involving 185 teeth. The observation period varied from 1 to 3 years. The clinical and radiographic findings revealed complete recovery in 59% of the involved teeth. The degree of periodontal and pulpal complications were closely related to the displacement between the fragments and to the type of fracture. Six different fracture types were classified with regard to the extent of involvement of the tooth supporting tissue; 23% of the teeth which initially responded negatively to electric stimulation showed positive sensibility at the time of reexamination. Thus, a long time observation period is advisable with regard to the final outcome of the pulp damage. Conservative treatment of teeth involved in the line of mandibular fractures has a favorable prognosis especially if optimal reduction of the jaw fragments is achieved.

  11. The length of teeth : A statistical analysis of the differences in length of human teeth for radiologic purposes

    NARCIS (Netherlands)

    Verhoeven, J.W.; Aken, J. van; Weerdt, G.P. van der

    1979-01-01

    Intraoral radiograms can be made according to the long tube paralleling technique utilizing aiming devices. An important factor in the design of these instruments is the length of the teeth to be radiographed. Reliable data regarding the length of the teeth in the different regions of the mouth are

  12. Anesthetic management in intrauterine surgery to evaluate an experimental model of myelomeningocele in non human primates (Macaca mulatta Anestesia em cirurgia intra-uterina para avaliar um modelo experimental de mielomeningocele em primatas não humanos (Macaca mulatta

    Directory of Open Access Journals (Sweden)

    Alfonso Galván-Montaño

    2010-06-01

    Full Text Available PURPOSE: Evaluate the anesthetic management in intrauterine surgery to induce myelomeningocele in non human primates Macaca mulatta. METHODS: A total of nine fetuses had intrauterine surgery; laminectomy was performed on them in L5 and L6. The studied variables were: maternal death, fetus death, cardiac frequency, respiratory frequency, arterial pressure, temperature, and oxygen saturation. RESULTS: No maternal or fetal deaths occurred; the only variable that was reported below the normal ranges was temperature. CONCLUSION: No maternal or fetal deaths occurred; the only variable that was reported below the normal ranges was temperature.OBJETIVO: Avaliar o manejo anestésico em cirurgia intra-uterina para induzir mielomeningocelo em primatas não humanos, Macaca mulatta. MÉTODOS: Operaram-se um total de nove fetos in útero que foram submetidos à laminectomia em L5 e L6. As variáveis a estudar foram mortes maternas ou fetais, freqüência cardíaca e respiratória, pressão arterial, temperatura e saturação de oxigênio. RESULTADOS: Não se apresentaram mortes maternas ou fetais, a temperatura se manteve abaixo dos 36°C, não tendo repercussões no bem-estar dos macacos. CONCLUSÃO: Não ocorreu nenhum óbito materno ou fetal, sendo que a única variável abaixo do normal foi a temperatura.

  13. A 25-year-old man with 50 teeth: Astonishing but true!!

    OpenAIRE

    Bhatia, Vishwas; Jain, Nitul; Bhatia, Garima; Garg, Rakesh

    2013-01-01

    Retained primary teeth is a well-known process but multiple retained primary, permanent, and supernumerary teeth that too in an asymptomatic, non-syndromic patient is a rare possibility that has rarely been reported in literature. This case report discusses the clinical and radiographic details along with treatment options in a 21-year-old patient having a total number of 50 teeth, i.e., 16 retained primary teeth, 32 permanent teeth, and 2 supernumerary teeth without being associated with any...

  14. Urinary excretion of cortisol from rhesus monkeys (Macaca mulatta) habituated to restraint

    Science.gov (United States)

    Wade, C. E.; Ortiz, R. M.

    1997-01-01

    Use of monkeys in research has often required that they be restrained in a chair. However, chair restraint can elicit an initial neuroendocrine stress response. Also, inactivity associated with restraint can induce muscular atrophy. We proposed that prior habituation of monkeys to chair restraint would attenuate these neuroendocrine responses without causing substantial muscle wasting. Four rhesus monkeys (Macaca mulatta) were trained and habituated to a restraint chair specifically designed for spaceflight. During the study, monkeys were placed in metabolic cages for 7 days (prerestraint, Phase I), placed in a chair restraint for 18 days (Phase II), and then returned to their metabolic cages for 5 days (postrestraint, Phase III). Urine was collected between 0700-1100 daily, and measurements of cortisol, creatinine, and electrolyte concentrations were adjusted for hourly excretion rates. Body weights of the monkeys did not change between start of the prerestraint and postrestraint phases (10.3 +/- 0.8 vs. 10.3 +/- 0.9 kg, respectively). During the 3 phases, mean excretion rate of cortisol did not change (24.1 +/- 10.3, 26.7 +/- 7.7, and 19.3 +/- 5.8 microg/h, respectively). Mean excretion rate of creatinine (37.3 +/- 7.5, 37.5 +/- 12.2, and 36.9 +/- 17.1 mg/h, respectively), Na+ (3.3 +/- 1.2, 3.2 +/- 1.2, 2.2 +/- 1.8 mmol/h, respectively), and K+ (5.3 +/- 1.8, 5.4 +/- 1.6, and 4.3 +/- 2.8 mmol/h, respectively) were also not altered. Lack of an increase in excreted urinary cortisol suggested that prior habituation to chair restraint attenuated neuroendocrine responses reported previously. Also, the chair restraint method used appeared to allow adequate activity, because the monkeys did not have indices of muscle wasting.

  15. Experimental oral toxicity of domoic acid in cynomolgus monkeys (Macaca fascicularis) and rats. Preliminary investigations.

    Science.gov (United States)

    Tryphonas, L; Truelove, J; Todd, E; Nera, E; Iverson, F

    1990-10-01

    A recent outbreak of marine food poisoning in humans was attributed to the consumption of blue mussels (Mytilus edulis L.) contaminated with domoic acid (DA) that was produced by the diatom Nitzschia pungens. The clinical and morphological effects of single oral doses of extracts of mussels contaminated with DA or of DA isolated from toxic mussels were investigated in small groups (one to six) of cynomolgus monkeys (Macaca fascicularis; 0.5-10 mg DA/kg body weight) and of Sprague-Dawley rats (60 to 80 mg DA/kg body weight). Control animals were either given saline or were not treated. To test whether monosodium glutamate, present in the food consumed by some affected humans, and dimethylsulphoxide, suspected of being present in the plankton, enhanced the response, monosodium glutamate (at 0.25% of mussel extract bolus) or dimethylsulphoxide (at 1 g per bolus) were co-administered to two (one each) of the DA-treated monkeys. DA-treated monkeys developed transient excitation characterized by vomiting. DA-treated rats showed withdrawal followed by hyperexcitation and death (in one case). Mild to moderate central nervous system lesions consistent with neuroexcitation were present in both monkeys and rats. The addition of monosodium glutamate and dimethylsulphoxide had no significant effect on the appearance and severity of central nervous system clinical signs and lesions. The wide variations in the response of test animals to orally administered DA were attributed to the protective effect of vomiting, and to suspected incomplete or slow gastro-intestinal absorption of the toxic agent. The results reinforce the view that DA is an emetic and that under appropriate conditions may also inflict excitotoxic central nervous system damage.

  16. Concealed fertility and extended female sexuality in a non-human primate (Macaca assamensis.

    Directory of Open Access Journals (Sweden)

    Ines Fürtbauer

    Full Text Available In numerous primates living in mixed-sex groups, females display probabilistic cues of fertility to simultaneously concentrate paternity to dominant males while diluting it amongst others as a means to reduce the risk of infanticide and to increase male care for offspring. A few species, however, lack these cues and potentially conceal fertility from males; yet, to date, little is known about mating patterns and their underlying proximate mechanisms in such species. Here, we investigated mating activity and sexual consortships relative to female reproductive state in wild Assamese macaques (Macaca assamensis, a species where females lack prominent anogenital swellings and copulation calls. During two mating seasons (2837 contact hours we recorded sexual and social behaviors, sexual consortships, and collected 1178 fecal samples (n = 15 females which were analyzed for progestogen concentrations to assess female reproductive state and to determine the timing of ovulation and conception. Although mostly conceiving in their first ovarian cycle, females were sexually receptive throughout the entire 4-month mating season, and within-cycle mating frequencies were not increased during fertile phases. Dominant males did not monopolize fertile matings, and consortships by high-ranking males lasted for long periods, which were not exclusively linked to female fertile phases. Furthermore, females copulated promiscuously but not randomly, i.e. for almost every female, matings were concentrated to a certain male, irrespective of male rank. Collectively, we demonstrate that fertility is undisclosed to males. The extreme extended female sexuality facilitated by concealed fertility may allow females to create differentiated mating relationships within a promiscuous mating system. Our study provides important new insight into the plasticity of female sexuality in non-human primates.

  17. Microvasculature of the Olfactory Organ in the Japanese Monkey (Macaca fuscata fuscata)

    Science.gov (United States)

    Okada, Shigenori; Schraufnagel, Dean E.

    2002-06-01

    Olfaction is an important and primitive sense. As its importance has changed with evolution, anatomic adjustments have occurred in its structure and vasculature. Primates are a family of vertebrates that have had to develop their visual system to adapt to the arboreal environment and have evolved from a macrosmatic to a microsmatic species as the optic system has enlarged. This has resulted in anatomic changes of a small but critical area at the base of the brain. This paper describes the three-dimensional vascular anatomy of the olfactory organ of the Japanese monkey (Macaca fuscata fuscata). This is best understood by dividing the organ into three parts: the olfactory tract, olfactory bulb, and olfactory nerves in the nasal mucosa. The bulb can be partitioned into an outer or cortical part and inner or medullary part. The vasculature and tissue were examined grossly and with light microscopy and scanning electron microscopy of vascular corrosion casts. The olfactory tract and bulb were supplied by an arteriole from the anterior cerebral artery on each side. The tract was supplied by capillaries running spirally with a coarse network. At the olfactory bulb, the arteriole ramified into the intracortical and medullary branches that formed capillary networks. The bulbar intracortical capillaries were divided into two layers with different densities and vascular patterns. The capillaries of the superficial layer had a ladder-like pattern. The branches that ran into the medulla of the olfactory bulb were more widely spaced. Twigs from the posterior ethmoidal artery ran along the nerve fiber and formed intra- and extrafascicular networks. Each region of the olfactory organ had characteristic three-dimensional vascular patterns that were related to their cellular architecture.

  18. Whom to groom and for what? Patterns of grooming in female Barbary macaques (Macaca sylvanus).

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    Roubová, Veronika; Konečná, Martina; Šmilauer, Petr; Wallner, Bernard

    2015-01-01

    Grooming is one of the most conspicuous social interactions among nonhuman primates. The selection of grooming partners can provide important clues about factors relevant for the distribution of grooming within a social group. We analyzed grooming behavior among 17 semi-free ranging female Barbary macaques (Macaca sylvanus). We tested whether grooming is related to kinship, rank and friendship. Furthermore, we tested whether grooming is reciprocated or exchanged for rank related benefits (i.e. lower aggression and increased tolerance whilst feeding). We found that in general grooming was reciprocally exchanged, directed up the hierarchy and at the same time affected by friendship and kinship. Grooming was more frequent among individuals with higher friendship values as well as amongst related individuals. We also divided our data set on the basis of rank difference and tested if different power asymmetries between individuals affected the tendency to exchange grooming for rank related benefits and grooming reciprocation. In support of our initial hypothesis our results show that the reciprocation of grooming was a significant predictor of grooming interactions between individuals of similar rank, but not between those individuals more distantly separated in the social hierarchy. However, we did not find any evidence for grooming being exchanged for rank related benefits in either data set. Our results, together with previously published studies, illustrate the behavioral flexibility of macaques. It is clear that multiple studies of the same species are necessary to gather the data required for the solid comparative studies needed to shed light on patterns of grooming behavior in primates.

  19. Feeding behavior and aggression in wild Siberut macaques (Macaca siberu) living under low predation risk.

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    Richter, Christin; Gras, Pierre; Hodges, Keith; Ostner, Julia; Schülke, Oliver

    2015-07-01

    Investigating which factors influence feeding competition is crucial for our understanding of the diversity of social relationships. Socio-ecological models differ in their predictions whether predation risk directly influences feeding competition and which factors exactly predict contest competition. We investigated feeding competition in Siberut macaques (Macaca siberu), a species endemic to Siberut Island (West Sumatra, Indonesia). Siberut macaques experience low predation risk, as major predators (felids, raptors) are absent. They are therefore appropriate subjects to test the prediction that low predation risk reduces feeding competition. To estimate contest potential, we quantified size, spatial distribution and density of food plants, and the availability of alternative resources. We recorded behavior in food patches using a modified focal tree method. Food patches, sorted by decreasing average feeding group size, included large trees (40% of focal plant observations), lianas/strangler (16%), medium trees (9%), small (palm) trees (20%), and rattan (15%). Most food patches were clumped but occurred at low densities relative to the area of average group spread. Thus, availability of alternative food patches was low. Although food patch characteristics indicate high contest potential, the observed aggression rate (0.13 bouts between adults/h) was low relative to other primates. Average feeding group size was small relative to total group size, and feeding group size matched crown volume. Perceived predation risk was low, based on spatial and feeding behavior of juveniles. Together, these results suggest that predation risk may influence feeding competition. Social and temporal factors (patch feeding time), but not ecological factors (fruit abundance in patch and forest, alternative resources) predicted aggression frequency in food patches. Overall, comparative data are still relatively scarce, and researchers should collect more data on group spread, sub

  20. Pyrosequencing as a method for SNP identification in the rhesus macaque (Macaca mulatta

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    Kanthaswamy S

    2008-05-01

    Full Text Available Abstract Background Rhesus macaques (Macaca mulatta are the primate most used for biomedical research, but phenotypic differences between Indian-origin and Chinese rhesus macaques have encouraged genetic methods for identifying genetic differences between these two populations. The completion of the rhesus genome has led to the identification of many single nucleotide polymorphisms (SNPs in this species. These single nucleotide polymorphisms have many advantages over the short tandem repeat (STR loci currently used to assay genetic variation. However, the number of currently identified polymorphisms is too small for whole genome analysis or studies of quantitative trait loci. To that end, we tested a combination of methods to identify large numbers of high-confidence SNPs, and screen those with high minor allele frequencies (MAF. Results By testing our previously reported single nucleotide polymorphisms, we identified a subset of high-confidence, high-MAF polymorphisms. Resequencing revealed a large number of regionally specific SNPs not identified through a single pyrosequencing run. By resequencing a pooled sample of four individuals, we reliably identified loci with a MAF of at least 12.5%. Finally, we found that when applied to a larger, geographically variable sample of rhesus, a large proportion of our loci were variable in both populations, and very few loci were ancestry informative. Despite this fact, the SNP loci were more effective at discriminating Indian and Chinese rhesus than STR loci. Conclusion Pyrosequencing and pooled resequencing are viable methods for the identification of high-MAF SNP loci in rhesus macaques. These SNP loci are appropriate for screening both the inter- and intra-population genetic variation.

  1. Maxillary nerve compression in cynomolgus monkey Macaca fascicularis: altered somatic sensation and peripheral nerve firing

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    Guo Ning

    2012-12-01

    Full Text Available Abstract Background Trigeminal nerve is a major source of the sensory input of the face, and trigeminal neuropathology models have been reported in rodents with injury to branches of the maxillary or mandibular division of the trigeminal nerve. Non-human primates are neuroanatomically more closely related to human than rodents; however, nerve injury studies in non-human primates are limited. Results We describe here a nerve injury model of maxillary nerve compression (MNC in the cynomolgus macaque monkey, Macaca fascicularis, and the initial characterization of the consequences of damage to this trigeminal nerve branch. The nerve injury from the compression appeared to be mild, as we did not observe overt changes in home-cage behavior in the monkeys. When mechanical stimulation was applied to the facial area, monkeys with MNC displayed increased mechanical sensitivity, as the avoidance response scores were lower than those from the control animals. Such a change in mechanical sensitivity appeared to be somewhat bilateral, as the contralateral side also showed increased mechanical sensitivity, although the change on the ipsilateral side was more robust. Multiple-unit recording of the maxillary nerve showed a general pattern of increasing responsiveness to escalating force in mechanical stimulation on the contralateral side. Ipsilateral side of the maxillary nerve showed a lack of responsiveness to escalating force in mechanical stimulation, possibly reflecting a maximum stimulation threshold effect from sensitized nerve due to MNC injury. Conclusions These results suggest that MNC may produce increased sensitivity of the ipsilateral maxillary nerve, and that this model may serve as a non-human primate model to evaluate the effect of injury to trigeminal nerve branches.

  2. When dispersal fails: unexpected genetic separation in Gibraltar macaques (Macaca sylvanus).

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    Modolo, Lara; Martin, Robert D; van Schaik, Carel P; van Noordwijk, Maria A; Krũtzen, Michael

    2008-09-01

    Barbary macaques (Macaca sylvanus), now restricted in the wild to a few isolated forested areas of Morocco and Algeria, are present in a free-ranging colony on Gibraltar. For many decades, the Gibraltar colony was exposed to multiple bottlenecks due to highly nonrandom removal of animals, followed by repeated introductions of animals from North Africa. Moreover, because of complete isolation, Gibraltar's several social groups of macaques provide an ideal system to study the genetic consequences of dispersal in cercopithecines in situ. Predictions of genetic consequences due to male-biased dispersal in cercopithecines will be different for autosomal and maternally inherited genetic markers, such as the control region of the mitochondrial DNA. We used a panel of 14 highly polymorphic microsatellite loci and part of the hypervariable region I of the mitochondrial control region to estimate genetic structure between five social groups in Gibraltar. Surprisingly, for autosomal markers, both classical summary statistics and an individual-based method using a Bayesian framework detected significant genetic structure between social groups in Gibraltar, despite much closer proximity than wild Algerian and Moroccan populations. Mitochondrial data support this finding, as a very substantial portion of the total genetic variation (70.2%) was found between social groups. Using two Bayesian approaches, we likewise identified not only a small number of male first-generation immigrants (albeit less than expected for cercopithecines) but also unexpectedly a few females. We hypothesize that the culling of males that are more likely to disperse might slow down genetic homogenization among neighbouring groups, but may also and more perversely produce selection on certain behavioural traits. This may have important repercussions for conservation, as it could lead to evolutionary changes that are not due to inbreeding or genetic drift.

  3. Patterns of infant handling and relatedness in Barbary macaques (Macaca sylvanus) on Gibraltar.

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    Kümmerli, Rolf; Martin, Robert D

    2008-10-01

    Among papionin primates, the Barbary macaque (Macaca sylvanus) shows the most extensive interactions between infants and group members other than the mother. Two different types of interactions occur: (1) long-lasting dyadic interactions between a handler and an infant, and (2) brief triadic interactions between two handlers involving an infant. Previous investigations showed that infant handling by males is best explained as use of infants to manage relationships with other males. In contrast, no adaptive explanation for infant handling by females emerged. Here, we compared the infant-handling pattern between subadult/adult males and subadult/adult females in a free-ranging group of 46 Barbary macaques on Gibraltar to test whether the relationship management hypothesis also applies to female handlers. We further investigated the infant-handling pattern of juveniles and used microsatellite markers to estimate relatedness between infant handlers and the infant's mother. We found that males, females and juveniles all participated extensively in triadic interactions using infants of above-average related females. In contrast, only males and juveniles were highly involved in dyadic interactions with infants of related females, while females rarely handled infants other than their own. The pattern of infant handling was entirely compatible with the predictions of the relationship management hypothesis for males and mostly so for females. Moreover, our genetic analysis revealed that males and females differ in their partner choice: while females preferred to interact with related females, males had no significant preference to interact with related males. We further discuss the observed above-average relatedness values between infant handlers and the infant's mother in the light of kin-selection theory.

  4. Factors increasing snake detection and perceived threat in captive rhesus macaques (Macaca mulatta).

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    Etting, Stephanie F; Isbell, Lynne A; Grote, Mark N

    2014-02-01

    The primary predators of primates are all ambush hunters, and yet felids, raptors, and snakes differ in aspects of their ecology that affect the evasive strategies of their primate prey. Felids and raptors can traverse long distances quickly, thus the urgency of threat they present increases as they come closer in proximity to primates. In contrast, snakes do not move rapidly over long distances, and so primates may be reasonably safe even at close distances provided snakes can be detected and monitored. We investigated the ability of captive rhesus macaques (Macaca mulatta) to detect snakes at distances ranging from 15 to 1.5 m. We also examined variation in intensity of perceived threat by applying a Hidden Markov Model to infer changes in underlying state from observable behaviors, that is, increased attention and mobbing. We found that the macaques often failed to detect snake models but that closer proximity improved snake detection, which is necessary before threat can be perceived. We also found that having only one individual in fairly close proximity (≤ 7.5 m) was sufficient to alert the rest of the group and so the chances of detection did not increase with increasing group size. Finally, we found that when the snakes were perceived, they did not elicit greater intensity of response with closer proximity. These results provide evidence that the threat from snakes is greatest when they are in proximity to primates but are unseen. When snakes are seen, however, distance appears not to affect primates' perceived risk, in contrast to their perceived risk from raptors and felids.

  5. Antimicrobial resistance in Campylobacter coli and Campylobacter jejuni in cynomolgus monkeys (Macaca fascicularis) and eradication regimens.

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    Koga, Tetsufumi; Aoki, Wataru; Mizuno, Takashi; Wakazono, Kuniko; Ohno, Junki; Nakai, Tsunehiro; Nomiya, Takao; Fujii, Miki; Fusegawa, Keiichi; Kinoshita, Kazuya; Hamada, Takakazu; Ikeda, Yoshinori

    2017-02-01

    Campylobacter spp. are zoonotic pathogens, however, knowledge about their presence and antimicrobial resistance in nonhuman primates is limited. Our animal facility purchased cynomolgus monkeys (Macaca fascicularis) from various Asian countries: China, Cambodia, Indonesia, the Philippines, and Vietnam. Colonization by Campylobacter spp. was investigated in 238 of the monkeys from 2009 to 2012 and antimicrobial susceptibility testing was carried out for these isolates. Furthermore, we eradicated these pathogens from these monkeys. Campylobacter spp. were isolated from 47 monkeys from three specific countries: China, Cambodia, and Indonesia, with respective isolation rates of 15%, 36%, and 67%. Two monkeys, which were each infected with Campylobacter jejuni and Campylobacter coli, showed clinical symptoms of diarrhea and bloody feces. In total, 41 isolates of C. coli and 17 isolates of C. jejuni were detected. Antimicrobial susceptibility varied: in the monkeys from China, erythromycin (ERY)-, tetracycline (TET)-, and ciprofloxacin-resistant C. coli, in the monkeys from Cambodia, amoxicillin-intermediate, TET- and ciprofloxacin-resistant C. coli and amoxicillin- and ciprofloxacin-resistant C. jejuni, and in the monkeys from Indonesia, ciprofloxacin-resistant C. coli and TET- and ciprofloxacin-resistant C. jejuni were common (>75%). Multiresistant isolates of C. coli were found in monkeys from all countries and multiresistant isolates of C. jejuni were found in monkeys from Indonesia. The eradication rate with azithromycin was comparable to that with gentamicin (GEN) by oral administration, and was higher than those with amoxicillin-clavulanic acid (AMC) and chloramphenicol (CHL). From the perspective of zoonosis, we should acknowledge multiresistant Campylobacter spp. isolated from the monkeys as a serious warning. Copyright © 2015. Published by Elsevier B.V.

  6. Auditory Rehabilitation in Rhesus Macaque Monkeys (Macaca mulatta) with Auditory Brainstem Implants

    Institute of Scientific and Technical Information of China (English)

    Zhen-Min Wang; Zhi-Jun Yang; Fu Zhao; Bo Wang; Xing-Chao Wang; Pei-Ran Qu; Pi-Nan Liu

    2015-01-01

    Background:The auditory brainstem implants (ABIs) have been used to treat deafness for patients with neurofibromatosis Type 2 and nontumor patients.The lack of an appropriate animal model has limited the study of improving hearing rehabilitation by the device.This study aimed to establish an animal model of ABI in adult rhesus macaque monkey (Macaca mulatta).Methods:Six adult rhesus macaque monkeys (M.mulatta) were included.Under general anesthesia,a multichannel ABI was implanted into the lateral recess of the fourth ventricle through the modified suboccipital-retrosigmoid (RS) approach.The electrical auditory brainstem response (EABR) waves were tested to ensure the optimal implant site.After the operation,the EABR and computed tomography (CT) were used to test and verify the effectiveness via electrophysiology and anatomy,respectively.The subjects underwent behavioral observation for 6 months,and the postoperative EABR was tested every two weeks from the 1st month after implant surgery.Result:The implant surgery lasted an average of 5.2 h,and no monkey died or sacrificed.The averaged latencies of peaks Ⅰ,Ⅱ and Ⅳ were 1.27,2.34 and 3.98 ms,respectively in the ABR.One-peak EABR wave was elicited in the operation,and one-or two-peak waves were elicited during the postoperative period.The EABR wave latencies appeared to be constant under different stimulus intensities;however,the amplitudes increased as the stimulus increased within a certain scope.Conclusions:It is feasible and safe to implant ABIs in rhesus macaque monkeys (M.mulatta) through a modified suboccipital RS approach,and EABR and CT are valid tools for animal model establishment.In addition,this model should be an appropriate animal model for the electrophysiological and behavioral study of rhesus macaque monkey with ABI.

  7. No-scalpel vasectomy by electrocauterization in free range rhesus macaques (Macaca mulatta

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    A. Raj

    2012-02-01

    Full Text Available The objective of the study was to standardize a new method of vasectomy in male rhesus macaques (Macaca mulatta. A total of 208 free range male rhesus macaques captured from different locations in Shivalik Hills in a population control programme of the rhesus macaques in India. General anaesthesia was achieved by using a combination of ketamine hydrochloride at 8 mg/kg body weight and xylazine hydrochloride at 2mg/kg body weight intramuscularly in squeeze cage. Surgical procedure of vasectomy was carried out by single-hole no-scalpel technique using a single pre-scrotal skin incision above the median raphae. Spermatic cord was grasped with ringed forceps and was pulled out through the single-hole incision. Vas deferens was separated from the artery-vein complexus and about 3-4 cm portion of vas deferens was resected. Cauterization of both ends of the vas deferens was achieved with electrocautery. The induction time for anaesthesia was 1.40±0.18 min while surgical time for vasectomy was found to be 5.09±0.22 min. Recovery from general anaesthesia was without side-effects after a mean duration of 36.07±1.22 min, whereas the duration of anaesthesia was observed to be 82.27±4.96 min. There were no major complications following the surgery and recovery of animals was smooth. Animals were kept in postoperative care for five days and released at the same capturing site.

  8. Diversity and molecular phylogeny of mitochondrial DNA of rhesus macaques (Macaca mulatta) in Bangladesh.

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    Hasan, M Kamrul; Feeroz, M Mostafa; Jones-Engel, Lisa; Engel, Gregory A; Kanthaswamy, Sree; Smith, David Glenn

    2014-11-01

    While studies of rhesus macaques (Macaca mulatta) in the eastern (e.g., China) and western (e.g., India) parts of their geographic range have revealed major genetic differences that warrant the recognition of two different subspecies, little is known about genetic characteristics of rhesus macaques in the transitional zone extending from eastern India and Bangladesh through the northern part of Indo-China, the probable original homeland of the species. We analyzed genetic variation of 762 base pairs of mitochondrial DNA from 86 fecal swab samples and 19 blood samples from 25 local populations of rhesus macaque in Bangladesh collected from January 2010 to August 2012. These sequences were compared with those of rhesus macaques from India, China, and Myanmar. Forty-six haplotypes defined by 200 (26%) polymorphic nucleotide sites were detected. Estimates of gene diversity, expected heterozygosity, and nucleotide diversity for the total population were 0.9599 ± 0.0097, 0.0193 ± 0.0582, and 0.0196 ± 0.0098, respectively. A mismatch distribution of paired nucleotide differences yielded a statistically significantly negative value of Tajima's D, reflecting a population that rapidly expanded after the terminal Pleistocene. Most haplotypes throughout regions of Bangladesh, including an isolated region in the southwestern area (Sundarbans), clustered with haplotypes assigned to the minor haplogroup Ind-2 from India reflecting an east to west dispersal of rhesus macaques to India. Haplotypes from the southeast region of Bangladesh formed a cluster with those from Myanmar, and represent the oldest rhesus macaque haplotypes of Bangladesh. These results are consistent with the hypothesis that rhesus macaques first entered Bangladesh from the southeast, probably from Indo-China, then dispersed westward throughout eastern and central India.

  9. Effects elicited by toxaphene in the cynomolgus monkey (Macaca fascicularis): a pilot study.

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    Bryce, F; Iverson, F; Andrews, P; Barker, M; Cherry, W; Mueller, R; Pulido, O; Hayward, S; Fernie, S; Arnold, D L

    2001-12-01

    Toxaphene, which was added to glycerol/corn oil, was administered at a level of 1 mg/kg body weight/day in gelatin capsules to four healthy young adult cynomolgus (Macaca fascicularis) monkeys for 52 weeks. Four control monkeys ingested capsules containing only glycerol/corn oil. Each group had two males and two females. On a daily basis, each monkey's feed and water consumption was determined, its health was monitored and the females were swabbed to evaluate menstrual status. On a weekly basis, each monkey's body weight was determined and a detailed clinical evaluation was performed. At 4-week intervals, blood samples were taken for serum biochemistry, haematology and toxaphene analysis. Also, a local anaesthetic was administered to the nuchal fat pad area of each monkey, and adipose samples were obtained for toxaphene analysis. 1 day prior to the biopsies, a 24-h urine and faecal collection was obtained for toxaphene analysis. After 34 weeks of treatment, the immune system of the monkeys was evaluated. After 52 weeks of dosing, all treated and two control animals were necropsied. Liver samples were obtained and microsomal fractions were prepared immediately. A portion of liver and kidney was taken for toxaphene analysis. All of the major internal organs were weighed and bone marrow evaluations were conducted. Organ and tissue samples were fixed in 10% formalin and processed for light microscopy. There was no effect of treatment on body weight gain, feed consumption, water consumption or haematological parameters. Two major clinical findings were inflammation and/or enlargement of the tarsal gland and impacted diverticulae in the upper and lower eye lids. At necropsy, the relative spleen and thymus weights were greater for the treated monkeys than the controls. Toxaphene administration produced an increase in metabolism of aminopyrene, methoxyresorufin and ethoxyresorufin, three substrates that are altered specifically by cytochrome P450-based hepatic

  10. Using biological markets principles to examine patterns of grooming exchange in Macaca thibetana.

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    Balasubramaniam, K N; Berman, C M; Ogawa, H; Li, J

    2011-12-01

    Biological markets principles offer testable hypotheses to explain variation in grooming exchange patterns among nonhuman primates. They predict that when within-group contest competition (WGC) is high and dominance hierarchies steep, grooming interchange with other "commodity" behaviors (such as agonistic support) should prevail. In contrast, when WGC is low and gradients shallow, market theory predicts that grooming reciprocity should prevail. We tested these predictions in a wild, provisioned Tibetan macaque (Macaca thibetana) group across six time periods during which the group had been subjected to varying degrees of range restriction. Data on female-female aggression, grooming, and support were collected using all-occurrences and focal animal sampling techniques, and analyzed using ANCOVA methods and correlation analyses. We found that hierarchical steepness varied significantly across periods, but did not correlate with two indirect indicators of WGC (group size and range restriction) in predicted directions. Contrary to expectations, we found a negative correlation between steepness and group size, perhaps because the responses of group members to external risks (i.e. prolonged and unavoidable exposure to humans) may have overshadowed the effects of WGC. As predicted, grooming reciprocity was significant in each period and negatively correlated with steepness, even after we controlled group size, kinship, rank differences, and proximity. In contrast, there was no evidence for grooming interchange with agonistic support or for a positive relationship between interchange and steepness. We hypothesize that stressful conditions and/or the presence of stable hierarchies during each period may have led to a greater market demand for grooming than support. We suggest that future studies testing these predictions consider more direct measures of WGC and commodities in addition to support, such as feeding tolerance and access to infants.

  11. Rhesus monkeys (Macaca mulatta detect rhythmic groups in music, but not the beat.

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    Henkjan Honing

    Full Text Available It was recently shown that rhythmic entrainment, long considered a human-specific mechanism, can be demonstrated in a selected group of bird species, and, somewhat surprisingly, not in more closely related species such as nonhuman primates. This observation supports the vocal learning hypothesis that suggests rhythmic entrainment to be a by-product of the vocal learning mechanisms that are shared by several bird and mammal species, including humans, but that are only weakly developed, or missing entirely, in nonhuman primates. To test this hypothesis we measured auditory event-related potentials (ERPs in two rhesus monkeys (Macaca mulatta, probing a well-documented component in humans, the mismatch negativity (MMN to study rhythmic expectation. We demonstrate for the first time in rhesus monkeys that, in response to infrequent deviants in pitch that were presented in a continuous sound stream using an oddball paradigm, a comparable ERP component can be detected with negative deflections in early latencies (Experiment 1. Subsequently we tested whether rhesus monkeys can detect gaps (omissions at random positions in the sound stream; Experiment 2 and, using more complex stimuli, also the beat (omissions at the first position of a musical unit, i.e. the 'downbeat'; Experiment 3. In contrast to what has been shown in human adults and newborns (using identical stimuli and experimental paradigm, the results suggest that rhesus monkeys are not able to detect the beat in music. These findings are in support of the hypothesis that beat induction (the cognitive mechanism that supports the perception of a regular pulse from a varying rhythm is species-specific and absent in nonhuman primates. In addition, the findings support the auditory timing dissociation hypothesis, with rhesus monkeys being sensitive to rhythmic grouping (detecting the start of a rhythmic group, but not to the induced beat (detecting a regularity from a varying rhythm.

  12. A behavioral taxonomy of loneliness in humans and rhesus monkeys (Macaca mulatta.

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    John P Capitanio

    Full Text Available Social relationships endow health and fitness benefits, but considerable variation exists in the extent to which individuals form and maintain salutary social relationships. The mental and physical health effects of social bonds are more strongly related to perceived isolation (loneliness than to objective social network characteristics. We sought to develop an animal model to facilitate the experimental analysis of the development of, and the behavioral and biological consequences of, loneliness. In Study 1, using a population-based sample of older adults, we examined how loneliness was influenced both by social network size and by the extent to which individuals believed that their daily social interactions reflected their own choice. Results revealed three distinct clusters of individuals: (i individuals with large networks who believed they had high choice were lowest in loneliness, (ii individuals with small social networks who believed they had low choice were highest in loneliness, and (iii the remaining two groups were intermediate and equivalent in loneliness. In Study 2, a similar three-group structure was identified in two separate samples of adult male rhesus monkeys (Macaca mulatta living in large social groups: (i those high in sociability who had complex social interaction with a broad range of social partners (putatively low in loneliness, (ii those low in sociability who showed tentative interactions with certain classes of social partners (putatively high in loneliness, and (iii those low in sociability who interacted overall at low levels with a broad range of social partners (putatively low or intermediate in loneliness. This taxonomy in monkeys was validated in subsequent experimental social probe studies. These results suggest that, in highly social nonhuman primate species, some animals may show a mismatch between social interest and social attainment that could serve as a useful animal model for experimental and

  13. A natural model of behavioral depression in postpartum adult female cynomolgus monkeys (Macaca fascicularis).

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    Chu, Xun-Xun; Dominic Rizak, Joshua; Yang, Shang-Chuan; Wang, Jian-Hong; Ma, Yuan-Ye; Hu, Xin-Tian

    2014-05-01

    Postpartum depression (PPD) is a modified form of major depressive disorders (MDD) that can exert profound negative effects on both mothers and infants than MDD. Within the postpartum period, both mothers and infants are susceptible; but because PPD typically occurs for short durations and has moderate symptoms, there exists challenges in exploring and addressing the underlying cause of the depression. This fact highlights the need for relevant animal models. In the present study, postpartum adult female cynomolgus monkeys (Macaca fascicularis) living in breeding groups were observed for typical depressive behavior. The huddle posture behavior was utilized as an indicator of behavioral depression postpartum (BDP) as it has been established as the core depressive-like behavior in primates. Monkeys were divided into two groups: A BDP group (n=6), which were found to spend more time huddling over the first two weeks postpartum than other individuals that formed a non-depression control group (n=4). The two groups were then further analyzed for locomotive activity, stressful events, hair cortisol levels and for maternal interactive behaviors. No differences were found between the BDP and control groups in locomotive activity, in the frequencies of stressful events experienced and in hair cortisol levels. These findings suggested that the postpartum depression witnessed in the monkeys was not related to external factors other than puerperium period. Interestingly, the BDP monkeys displayed an abnormal maternal relationship consisting of increased infant grooming. Taken together, these findings suggest that the adult female cynomolgus monkeys provide a natural model of behavioral postpartum depression that holds a number of advantages over commonly used rodent systems in PPD modeling. The cynomolgus monkeys have a highly-organized social hierarchy and reproductive characteristics without seasonal restriction-similar to humans-as well as much greater homology to humans

  14. Urban primate ranging patterns: GPS-collar deployments for Macaca fascicularis and M. sylvanus.

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    Klegarth, Amy R; Hollocher, Hope; Jones-Engel, Lisa; Shaw, Eric; Lee, Benjamin P Y-H; Feeney, Tessa; Holmes, Damian; Laguea, Dale; Fuentes, Agustín

    2017-05-01

    The global increase in urbanization is leading to heavier interface between humans and wildlife. Within these anthropogenic landscapes, little is known about ranging patterns, particularly with regard to urban primates. Here we present the results of the first long-term deployment of multiple GPS collars on two species of macaques to investigate the impacts of urbanization on urban primate ranging patterns in Singapore and Gibraltar. Collars data acquisition were excellent with respect to the amount, quality, and accuracy of data collected; however, remote connectivity and drop-off functionality was poor across all deployments. Analyses highlighted high variability in ranging patterns between individuals within each species that aligned with access to human food resources and patterns of tourism. Individuals from troops with less access to human food had much larger home, core, and day ranges relative to those with regular provisioning or raiding opportunities. Almost no temporal range overlap was observed between any focal individuals at either site and spatial overlap was low for all but two troops at each site. We found no relationship between anthropogenic schedules and changes in ranging patterns. Significant seasonal variation existed for daily path length and day range size for both the Singapore long-tailed and the Gibraltar Barbary macaques, with long-tailed macaques increasing their range during the equatorial monsoon season and Barbary macaques increasing their range during drier, summer months. This study highlights how the behavioral plasticity found within the genus Macaca is reflected in ranging pattern variability within urban environments. © 2017 Wiley Periodicals, Inc.

  15. Concealed Fertility and Extended Female Sexuality in a Non-Human Primate (Macaca assamensis)

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    Fürtbauer, Ines; Heistermann, Michael; Schülke, Oliver; Ostner, Julia

    2011-01-01

    In numerous primates living in mixed-sex groups, females display probabilistic cues of fertility to simultaneously concentrate paternity to dominant males while diluting it amongst others as a means to reduce the risk of infanticide and to increase male care for offspring. A few species, however, lack these cues and potentially conceal fertility from males; yet, to date, little is known about mating patterns and their underlying proximate mechanisms in such species. Here, we investigated mating activity and sexual consortships relative to female reproductive state in wild Assamese macaques (Macaca assamensis), a species where females lack prominent anogenital swellings and copulation calls. During two mating seasons (2837 contact hours) we recorded sexual and social behaviors, sexual consortships, and collected 1178 fecal samples (n = 15 females) which were analyzed for progestogen concentrations to assess female reproductive state and to determine the timing of ovulation and conception. Although mostly conceiving in their first ovarian cycle, females were sexually receptive throughout the entire 4-month mating season, and within-cycle mating frequencies were not increased during fertile phases. Dominant males did not monopolize fertile matings, and consortships by high-ranking males lasted for long periods, which were not exclusively linked to female fertile phases. Furthermore, females copulated promiscuously but not randomly, i.e. for almost every female, matings were concentrated to a certain male, irrespective of male rank. Collectively, we demonstrate that fertility is undisclosed to males. The extreme extended female sexuality facilitated by concealed fertility may allow females to create differentiated mating relationships within a promiscuous mating system. Our study provides important new insight into the plasticity of female sexuality in non-human primates. PMID:21853074

  16. Choriodecidual infection downregulates angiogenesis and morphogenesis pathways in fetal lungs from Macaca nemestrina.

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    Ryan M McAdams

    Full Text Available BACKGROUND: Intrauterine exposure to amniotic fluid (AF cytokines is thought to predispose to bronchopulmonary dysplasia (BPD. We evaluated the effects of GBS exposure on RNA expression in fetal lung tissue to determine early molecular pathways associated with fetal lung injury that may progress to BPD. METHODS: Ten chronically catheterized pregnant monkeys (Macaca nemestrina at 118-125 days gestation (term = 172 days received choriodecidual inoculation of either: 1 Group B Streptococcus (n = 5 or 2 saline (n = 5. Cesarean section and fetal necropsy was performed in the first week after GBS or saline inoculation regardless of labor. RNA was extracted from fetal lungs and profiled by microarray. Results were analyzed using single gene, Gene Set, and Ingenuity Pathway Analysis. Validation was by RT-PCR and immunohistochemistry. RESULTS: Despite uterine quiescence in most cases, fetal lung injury occurred in four GBS cases (intra-alveolar neutrophils, interstitial thickening and one control (peri-mortem hemorrhage. Significant elevations of AF cytokines (TNF-α, IL-8, IL-1β, IL-6 were detected in GBS versus controls (p<0.05. Lung injury was not directly caused by GBS, because GBS was undetectable by culture and PCR in the AF and fetal lungs. A total of 335 genes were differentially expressed greater than 1.5 fold (p<0.05 with GBS exposure associated with a striking upregulation of genes in innate and adaptive immunity and downregulation of pathways for angiogenesis, morphogenesis, and cellular growth and development. CONCLUSIONS: A transient choriodecidual infection may induce fetal lung injury with profound alterations in the genetic program of the fetal lung before signs of preterm labor. Our results provide a window for the first time into early molecular pathways disrupting fetal lung angiogenesis and morphogenesis before preterm labor occurs, which may set the stage for BPD. A strategy to prevent BPD should target the fetus in

  17. Stimulus-Food Pairings Produce Stimulus-Directed Touch Screen Responding in Cynomolgus Monkeys ("Macaca Fascicularis") with or without a Positive Response Contingency

    Science.gov (United States)

    Bullock, Christopher E.; Myers, Todd M.

    2009-01-01

    Acquisition and maintenance of touch-screen responding was examined in naive cynomolgus monkeys ("Macaca fascicularis") under automaintenance and classical conditioning arrangements. In the first condition of Experiment 1, we compared acquisition of screen touching to a randomly positioned stimulus (a gray square) that was either stationary or…

  18. A Curriculum Vitae of Teeth: Evolution, Generation, Regeneration

    Directory of Open Access Journals (Sweden)

    Despina S. Koussoulakou, Lukas H. Margaritis, Stauros L. Koussoulakos

    2009-01-01

    Full Text Available The ancestor of recent vertebrate teeth was a tooth-like structure on the outer body surface of jawless fishes. Over the course of 500,000,000 years of evolution, many of those structures migrated into the mouth cavity. In addition, the total number of teeth per dentition generally decreased and teeth morphological complexity increased. Teeth form mainly on the jaws within the mouth cavity through mutual, delicate interactions between dental epithelium and oral ectomesenchyme. These interactions involve spatially restricted expression of several, teeth-related genes and the secretion of various transcription and signaling factors. Congenital disturbances in tooth formation, acquired dental diseases and odontogenic tumors affect millions of people and rank human oral pathology as the second most frequent clinical problem. On the basis of substantial experimental evidence and advances in bioengineering, many scientists strongly believe that a deep knowledge of the evolutionary relationships and the cellular and molecular mechanisms regulating the morphogenesis of a given tooth in its natural position, in vivo, will be useful in the near future to prevent and treat teeth pathologies and malformations and for in vitro and in vivo teeth tissue regeneration.

  19. A curriculum vitae of teeth: evolution, generation, regeneration.

    Science.gov (United States)

    Koussoulakou, Despina S; Margaritis, Lukas H; Koussoulakos, Stauros L

    2009-01-01

    The ancestor of recent vertebrate teeth was a tooth-like structure on the outer body surface of jawless fishes. Over the course of 500,000,000 years of evolution, many of those structures migrated into the mouth cavity. In addition, the total number of teeth per dentition generally decreased and teeth morphological complexity increased. Teeth form mainly on the jaws within the mouth cavity through mutual, delicate interactions between dental epithelium and oral ectomesenchyme. These interactions involve spatially restricted expression of several, teeth-related genes and the secretion of various transcription and signaling factors. Congenital disturbances in tooth formation, acquired dental diseases and odontogenic tumors affect millions of people and rank human oral pathology as the second most frequent clinical problem. On the basis of substantial experimental evidence and advances in bioengineering, many scientists strongly believe that a deep knowledge of the evolutionary relationships and the cellular and molecular mechanisms regulating the morphogenesis of a given tooth in its natural position, in vivo, will be useful in the near future to prevent and treat teeth pathologies and malformations and for in vitro and in vivo teeth tissue regeneration.

  20. Estimation of age from development and eruption of teeth

    Directory of Open Access Journals (Sweden)

    B. S. Manjunatha

    2014-01-01

    Full Text Available The developing dentition is used to assess maturity and estimate the age in many disciplines including anthropology, archeology, forensic science, pediatric dentistry and orthodontics. There is evidence that dental development is less effected than skeletal development by malnutrition and hormonal disorders. There are two methods of dental age assessment, radiographically and by clinically visualization of eruption of teeth. The clinical method to assess dental age is based on the emergence of teeth in the mouth. This method is more suitable since it does not require any special equipment, expertise and is more economical. Tooth formation is the best choice for estimating the age as variations are less as compared to other development factors. Eruption of teeth is one of the changes observed easily among the various dynamic changes that occur from the formation of teeth to the final shedding of teeth. The times of eruption of teeth are fairly constant and this can be made use of in ascertaining the average age of eruption of the tooth. Assessment of age of an individual by examination of teeth is one of the accepted methods of age determination.

  1. Indirect pulp therapy: an alternative to pulpotomy in primary teeth.

    Science.gov (United States)

    Seale, N Sue

    2010-11-01

    Preservation of the primary teeth until their normal exfoliation is essential for normal oral function and facial growth of the child. To that end, treatment of primary teeth with large carious lesions approximating the pulp should be aimed at preserving the tooth. Currently, the pulpotomy is the most frequently used pulp treatment for cariously involved primary teeth. The purpose of this manuscript is to describe the use of an alternative to the pulpotomy, indirect pulp therapy (IPT), for the treatment of vital, primary teeth with carious involvement approaching the pulp. Accurate diagnosis of the vitality status of the pulp is critical to the success of IPT and involves careful radiographic and clinical assessment of the teeth to be sure they are healthy or at worst, reversibly inflamed. The indications for IPT are the same as for pulpotomy. The technique involves one appointment, requires that some carious dentin be left to avoid pulp exposure and requires the placement of a biologically sealing base and sealing final restoration. Teeth treated with IPT have success rates at least as good as those treated with pulpotomies, and IPT offers an acceptable alternative to pulpotomy as a treatment for vital, asymptomatic, cariously involved primary teeth.

  2. Structure, composition, and mechanical properties of shark teeth.

    Science.gov (United States)

    Enax, Joachim; Prymak, Oleg; Raabe, Dierk; Epple, Matthias

    2012-06-01

    The teeth of two different shark species (Isurus oxyrinchus and Galeocerdo cuvier) and a geological fluoroapatite single crystal were structurally and chemically characterized. In contrast to dentin, enameloid showed sharp diffraction peaks which indicated a high crystallinity of the enameloid. The lattice parameters of enameloid were close to those of the geological fluoroapatite single crystal. The inorganic part of shark teeth consisted of fluoroapatite with a fluoride content in the enameloid of 3.1 wt.%, i.e., close to the fluoride content of the geological fluoroapatite single crystal (3.64 wt.%). Scanning electron micrographs showed that the crystals in enameloid were highly ordered with a special topological orientation (perpendicular towards the outside surface and parallel towards the center). By thermogravimetry, water, organic matrix, and biomineral in dentin and enameloid of both shark species were determined. Dentin had a higher content of water, organic matrix, and carbonate than enameloid but contained less fluoride. Nanoindentation and Vicker's microhardness tests showed that the enameloid of the shark teeth was approximately six times harder than the dentin. The hardness of shark teeth and human teeth was comparable, both for dentin and enamel/enameloid. In contrast, the geological fluoroapatite single crystal was much harder than both kinds of teeth due to the absence of an organic matrix. In summary, the different biological functions of the shark teeth ("tearing" for Isurus and "cutting" for Galeocerdo) are controlled by the different geometry and not by the chemical or crystallographic composition.

  3. Frequency of intrusive luxation in deciduous teeth and its effects.

    Science.gov (United States)

    Carvalho, Vivian; Jacomo, Diana Ribeiro; Campos, Vera

    2010-08-01

    The aims of this study were three-fold: First, to determine the prevalence of partial and total intrusion of the primary anterior teeth. Second, to investigate the sequelae of total and partial intrusive luxation in the primary anterior teeth and in their successors and finally, to establish whether the sequelae on both deciduous and permanent teeth were related to the child's age at the time of the intrusion. Data collected from records of 169 boys and 138 girls, all between the ages of zero and 10 years, who were undergoing treatment during the period of March 1996 to December 2004. The sample was composed of 753 traumatized deciduous teeth, of which 221 presented intrusive luxation injury. Children with ages ranging from one to 4 years were the most affected with falls being the main cause of intrusion. Of all intruded teeth 128 (57.9%) were totally intruded and 93 (42.1%) partially. Pulp necrosis/premature loss and color change were the most frequent sequelae in both total and partial intrusions. Concerning permanent dentition, the most common disturbances were color change and/or enamel hypoplasia. Both types of intrusion caused eruption disturbance. Total intrusion was the most frequent type of intrusive luxation. There was no significant correlation between the child's age at the time of intrusion and the frequency of subsequent sequela on primary injured teeth (P = 0.035), between the age at the time of injury and the developmental disturbances on permanent teeth (P = 0.140).

  4. The post-mortem pink teeth phenomenon: a case report.

    Science.gov (United States)

    Soriano, Evelyne-Pessoa; Carvalho, Marcus-Vitor-Diniz de; Santos, Francisco-Bernardo Dos; Mendoza, Clóvis-César de; Araújo, Maria-do Socorro-Dantas de; Campello, Reginaldo-Inojosa-Carneiro

    2009-07-01

    This study presents the case of the post-mortem pink teeth phenomenon observed during an autopsy procedure performed on the body of a man who was kidnapped and murdered approximately 30 days before the examination. The corpse was in an advanced stage of decomposition and putrefaction. Both maxillary and jaw bones were intact, as well as the permanent teeth which presented the "pink teeth phenomenon", probably due to a haemorrhage in the pulp chambers. The pink discolouration was most pronounced at the neck of the teeth. The cause of death was asphyxia. Although the examiners stressed that post-mortem pink teeth must not be considered as a reliable odontological parameter for determining the cause of death, the results of other studies have shown that the pink teeth phenomenon is a common finding related to cases of asphyxia such as strangulation, drowning or suffocation. Thus, the pink teeth phenomenon must be studied in order to determine its role as a post-mortem finding. As of now, an exact relationship between the cause of death and this phenomenon remains unknown.

  5. Facial paralysis and lymphocytic facial neuritis in a rhesus macaque (Macaca mulatta) positive for simian retrovirus type D2.

    Science.gov (United States)

    Hampton, Anna L; Colby, Lesley A; Bergin, Ingrid L

    2011-12-01

    Simian retrovirus type D (SRVD) is a naturally occurring betaretrovirus in nonhuman primates of the genus Macaca. Infection can lead to a variety of clinical, hematologic, and histopathologic abnormalities. We report an unusual clinical presentation of facial paralysis and histologic lymphocytic neuritis in an SRVD type 2 (SRVD2)-infected rhesus macaque (Macaca mulatta) with a catheter-associated vena caval thrombus, anemia, thrombocytopenia, and multisystemic lymphoid hyperplasia. At initial presentation, a right atrial mass was detected by echocardiography. The macaque was clinically asymptomatic but had persistent anemia, thrombocytopenia, hyperglobulinemia, and later neutropenia. It was seropositive for SRV and PCR-positive for SRVD 2. Approximately 1 mo after initial presentation, the macaque developed right facial paralysis and was euthanized. Histologic lesions included lymphoplasmacytic aggregates affecting multiple organs, consistent with SRV-related lymphoid hyperplasia. The right facial nerve showed lymphoplasmacytic inflammation. The nerve itself was negative immunohistochemically for SRV antigen, but antigen was present infrequently in pericapillary lymphoid cells within the facial nerve and abundantly within lymphoid aggregates in the adjacent parotid salivary gland, bone marrow, and soft tissue. Known neurotropic viruses could not be identified. Given the widespread inflammation in this macaque, particularly in the area surrounding the facial nerve, lymphocytic neuritis and facial paralysis likely were an indirect effect of SRV infection due to local extension of SRV-related inflammation in the surrounding tissue.

  6. Methodological aspects of EPR dosimetry with teeth

    Energy Technology Data Exchange (ETDEWEB)

    Sholom, S.; Chumak, V. [Scientific Center for Radiation Medicine, Kiev (Ukraine)

    2001-07-01

    EPR dosimetry with tooth enamel is known today as one of the most reliable and accurate methods of retrospective dosimetry. In the present study a comprehensive analysis of influence of the major confounding factors (solar UV exposure and dental X-ray diagnostic procedures) on the accuracy of accidental dose reconstruction is given. In this analysis, the facts known from literature as well as own authors' results were considered. Among the latter it is worth to mention study of doses in enamel caused by X-ray diagnostic procedures as well as investigation of dose profiles in front teeth, which are most affected to solar radiation. As a main result, the variant of dosimetric technique is proposed. It comprises the optimal combination of strongest sides of existing techniques which allows to conduct routine reconstruction of accidental doses as low as few tens of mGy with errors of the same order of magnitude. The proposed technique is primarily destined for dosimetry of Chernobyl liquidators, but could be used for reconstruction of doses of other over-exposed categories. (orig.)

  7. Oral biofilm architecture on natural teeth.

    Science.gov (United States)

    Zijnge, Vincent; van Leeuwen, M Barbara M; Degener, John E; Abbas, Frank; Thurnheer, Thomas; Gmür, Rudolf; Harmsen, Hermie J M

    2010-02-24

    Periodontitis and caries are infectious diseases of the oral cavity in which oral biofilms play a causative role. Moreover, oral biofilms are widely studied as model systems for bacterial adhesion, biofilm development, and biofilm resistance to antibiotics, due to their widespread presence and accessibility. Despite descriptions of initial plaque formation on the tooth surface, studies on mature plaque and plaque structure below the gum are limited to landmark studies from the 1970s, without appreciating the breadth of microbial diversity in the plaque. We used fluorescent in situ hybridization to localize in vivo the most abundant species from different phyla and species associated with periodontitis on seven embedded teeth obtained from four different subjects. The data showed convincingly the dominance of Actinomyces sp., Tannerella forsythia, Fusobacterium nucleatum, Spirochaetes, and Synergistetes in subgingival plaque. The latter proved to be new with a possibly important role in host-pathogen interaction due to its localization in close proximity to immune cells. The present study identified for the first time in vivo that Lactobacillus sp. are the central cells of bacterial aggregates in subgingival plaque, and that Streptococcus sp. and the yeast Candida albicans form corncob structures in supragingival plaque. Finally, periodontal pathogens colonize already formed biofilms and form microcolonies therein. These in vivo observations on oral biofilms provide a clear vision on biofilm architecture and the spatial distribution of predominant species.

  8. Oral biofilm architecture on natural teeth.

    Directory of Open Access Journals (Sweden)

    Vincent Zijnge

    Full Text Available Periodontitis and caries are infectious diseases of the oral cavity in which oral biofilms play a causative role. Moreover, oral biofilms are widely studied as model systems for bacterial adhesion, biofilm development, and biofilm resistance to antibiotics, due to their widespread presence and accessibility. Despite descriptions of initial plaque formation on the tooth surface, studies on mature plaque and plaque structure below the gum are limited to landmark studies from the 1970s, without appreciating the breadth of microbial diversity in the plaque. We used fluorescent in situ hybridization to localize in vivo the most abundant species from different phyla and species associated with periodontitis on seven embedded teeth obtained from four different subjects. The data showed convincingly the dominance of Actinomyces sp., Tannerella forsythia, Fusobacterium nucleatum, Spirochaetes, and Synergistetes in subgingival plaque. The latter proved to be new with a possibly important role in host-pathogen interaction due to its localization in close proximity to immune cells. The present study identified for the first time in vivo that Lactobacillus sp. are the central cells of bacterial aggregates in subgingival plaque, and that Streptococcus sp. and the yeast Candida albicans form corncob structures in supragingival plaque. Finally, periodontal pathogens colonize already formed biofilms and form microcolonies therein. These in vivo observations on oral biofilms provide a clear vision on biofilm architecture and the spatial distribution of predominant species.

  9. Periodontics: 8. Periodontal problems associated with compromised anterior teeth.

    Science.gov (United States)

    Byrne, Patrick J; Irwin, Chris; Mullally, Brian; Allen, Edith; Ziada, Hassan

    2008-01-01

    Periodontal disease can significantly impact on the appearance of the anterior teeth. Prior to any definitive treatment, stabilization of the periodontal condition is a requirement. Treatment options can range from the placement of simple restorations, through orthodontic realignment, to the extraction and replacement of hopeless teeth. Each treatment plan must be individually tailored to the patient and level of periodontal disease, and must include provision for maintenance periodontal therapy. Periodontal diseases may compromise the prognosis of anterior teeth. Management is challenging and clinicians should take into consideration the short and long-term survival in treatment planning.

  10. Pulp response to Enamelite restorations in teeth of rhesus monkeys.

    Science.gov (United States)

    Amet, E M; Sayegh, F S

    1977-01-01

    The average magnitudes of cellular displacements, superficial responses, and deep responses were less for specimens restored with ZOE than for Enamelite specimens at the 1 week postoperative period. Of 20 teeth treated, three abscesses were found in the 1 week Enamelite postoperative period when the remaining dentin was 0.3 mm. or less. This indicates the presence of ingredients that are toxic to the pulp when there is little remaining dentin or when the material is placed directly over an exposure. Teeth restored with Enamelite in the 6 week group had values comparable to the ZOE teeth for the same time period.

  11. POST-MORTEM CHANGES IN TEETH- FORENSIC ISSUES

    Directory of Open Access Journals (Sweden)

    Irina MANOILESCU

    2015-12-01

    Full Text Available Teeth have an increased resistance to environmental factors and decomposition processes, which makes them highly valuable in forensic investigations. The either physical (wind, water, sun, soil type or biological (plant roots, insects, animals environmental factors and the decomposition processes induce post-mortem changes in teeth, which are relevant to forensic investigation in terms of estimating the post-mortem interval or of elucidating the conditions in which the body stood after death. In this paper, based on the data provided in the literature, the authors present the main changes induced by environmental factors and decomposition processes in teeth and refer to their relevance in forensic activity.

  12. Treatment of avulsed teeth with Emdogain--a case report.

    Science.gov (United States)

    Caglar, Esber; Tanboga, Ilknur; Süsal, Seckin

    2005-02-01

    The present case report describes the reimplantation of avulsed teeth with the treatment of Emdogain. Case was avulsed right maxillary permanent central and lateral incisor in a 9-year-old girl suffering from a traumatic injury. After pretreatment of avulsed teeth, Emdogain was applied to the root surface and into the extraction socket with subsequent replantation of the tooth. Evaluation parameters included horizontal and vertical percussion sound and periapical radiographs. At 1-2-6-12-month follow-up period, the clinical and radiographic appearance of the teeth showed resolution of mobility and no signs of replacement resorbption.

  13. Indirect porcelain veneer technique for restoring intrinsically stained teeth.

    Science.gov (United States)

    Cutbirth, S T

    1992-01-01

    Indirect porcelain veneers are often the ideal restoration for intrinsically stained teeth. This article details a step-by-step procedure for esthetically restoring discolored teeth. Porcelain laminate veneers are often indicated when teeth bleaching or direct composite bonding procedures cannot provide the desired esthetic result. Veneers are more appealing to many patients than full coverage crowns because of the more conservative tooth preparation required. If technique details are followed meticulously and cases are appropriately selected, porcelain veneers are not only durable but also promote marvelous gingival health and may be the most esthetic anterior dental restoration.

  14. Procedure for the automatic mesh generation of innovative gear teeth

    Directory of Open Access Journals (Sweden)

    Radicella Andrea Chiaramonte

    2016-01-01

    Full Text Available After having described gear wheels with teeth having the two sides constituted by different involutes and their importance in engineering applications, we stress the need for an efficient procedure for the automatic mesh generation of innovative gear teeth. First, we describe the procedure for the subdivision of the tooth profile in the various possible cases, then we show the method for creating the subdivision mesh, defined by two series of curves called meridians and parallels. Finally, we describe how the above procedure for automatic mesh generation is able to solve specific cases that may arise when dealing with teeth having the two sides constituted by different involutes.

  15. Bilateral supernumerary teeth in deciduous dentition-a rarity.

    Science.gov (United States)

    Acharya, Sonu; Ghosh, Chiranjit; Mondal, Pradeep Kumar

    2014-05-01

    Supernumerary teeth are considered as one of the most significant dental anomalies during the primary and early mixed dentition stages. They are of great concern to the dentists and parents because of the eruption, occlusal, and esthetic problems they can cause. Supernumerary teeth occur more frequently in the permanent dentition but rarely in primary dentition and more often seen in males. A supernumerary tooth in the primary dentition can cause ectopic or delayed eruption of permanent central incisors which will further alter occlusion and may compromise esthetics and formation of dentigerous cysts. Here we discuss a case of bilateral supernumerary teeth in deciduous dentition in a female child.

  16. Comparison of Periodontal Ligament Stem Cells Isolated from the Periodontium of Healthy Teeth and Periodontitis-Affected Teeth

    Directory of Open Access Journals (Sweden)

    Sara Soheilifar

    2016-11-01

    Full Text Available Objectives: Stem cell (SC therapy is a promising technique for tissue regeneration. This study aimed to compare the viability and proliferation ability of periodontal ligament stem cells (PDLSCs isolated from the periodontium of healthy and periodontitis-affected teeth to obtain an autologous, easily accessible source of SCs for tissue regeneration in periodontitis patients.Materials and Methods: The PDLSCs were isolated from the roots of clinically healthy premolars extracted for orthodontic purposes and periodontally involved teeth with hopeless prognosis (with and without phase I periodontal treatment. Cells were cultured and viability and proliferation ability of third passage cells in each group were evaluated using the methyl thiazol tetrazolium assay. The results were statistically analyzed using t-test.Results: No SCs could be obtained from periodontitis-affected teeth without phase I periodontal treatment. The viability of cells was 0.86±0.13 OD/540 in healthy group and 0.4±0.25 OD/540 in periodontitis-affected group (P=0.035. The proliferation ability (population doubling time of cells obtained from healthy teeth was 4.22±1.23 hours. This value was 2.3±0.35 hours for those obtained from periodontitis-affected teeth (P=0.02.Conclusions: Viability and proliferation ability of cells isolated from the periodontium of healthy teeth were significantly greater than those of cells isolated from the periodontitis-affected teeth.Keywords: Stem Cells; Periodontitis; Tooth; Regeneration

  17. Comparison of Periodontal Ligament Stem Cells Isolated from the Periodontium of Healthy Teeth and Periodontitis-Affected Teeth

    Science.gov (United States)

    Soheilifar, Sara; Amiri, Iraj; Bidgoli, Mohsen; Hedayatipanah, Morad

    2016-01-01

    Objectives: Stem cell (SC) therapy is a promising technique for tissue regeneration. This study aimed to compare the viability and proliferation ability of periodontal ligament stem cells (PDLSCs) isolated from the periodontium of healthy and periodontitis-affected teeth to obtain an autologous, easily accessible source of SCs for tissue regeneration in periodontitis patients. Materials and Methods: The PDLSCs were isolated from the roots of clinically healthy premolars extracted for orthodontic purposes and periodontally involved teeth with hopeless prognosis (with and without phase I periodontal treatment). Cells were cultured and viability and proliferation ability of third passage cells in each group were evaluated using the methyl thiazol tetrazolium assay. The results were statistically analyzed using t-test. Results: No SCs could be obtained from periodontitis-affected teeth without phase I periodontal treatment. The viability of cells was 0.86±0.13 OD/540 in healthy group and 0.4±0.25 OD/540 in periodontitis-affected group (P=0.035). The proliferation ability (population doubling time) of cells obtained from healthy teeth was 4.22±1.23 hours. This value was 2.3±0.35 hours for those obtained from periodontitis-affected teeth (P=0.02). Conclusions: Viability and proliferation ability of cells isolated from the periodontium of healthy teeth were significantly greater than those of cells isolated from the periodontitis-affected teeth.

  18. Multiple teeth fractures in dentinogenesis imperfecta: a case report.

    Science.gov (United States)

    Min, Boram; Song, Je Seon; Lee, Jae-Ho; Choi, Byung-Jai; Kim, Kwang-Mahn; Kim, Seong-Oh

    2014-01-01

    Dentinogenesis imperfecta (DGI) is a hereditary defect consisting of opalescent teeth composed of irregularly formed and hypomineralized dentin. This paper presents the multiple fractures of DGI-affected teeth and suggests the reason of low fracture resistance by observing the dentin microstructures directly using scanning electron microscope (SEM) and by measuring its surface hardness using the Vickers hardness test. SEM revealed that while the enamel microstructure was similar in the DGI-affected and normal teeth, the microstructure of the DGI-affected dentin was poorly woven and more loosely packed than that of the normal dentin. The Vickers hardness of the DGI-affected dentin was 4.89 times softer than the normal dentin. The low fracture resistance of DGI-affected teeth can be attributed to the poorly woven microstructure of their dentin, which leads to a reduction in hardness.

  19. Pins, dowels, and other retentive devices in posterior teeth.

    Science.gov (United States)

    Jacobi, R; Shillingburg, H T

    1993-07-01

    Devices used to increase retention of restorations to severely damaged posterior teeth are described, with an emphasis on pins and dowels. Advantages and disadvantages of different techniques and measures to help prevent and correct problems are presented.

  20. Real-Time Rendering of Teeth with No Preprocessing

    DEFF Research Database (Denmark)

    Larsen, Christian Thode; Frisvad, Jeppe Revall; Jensen, Peter Dahl Ejby

    2012-01-01

    We present a technique for real-time rendering of teeth with no need for computational or artistic preprocessing. Teeth constitute a translucent material consisting of several layers; a highly scattering material (dentine) beneath a semitransparent layer (enamel) with a transparent coating (saliva......). In this study we examine how light interacts with this multilayered structure. In the past, rendering of teeth has mostly been done using image-based texturing or volumetric scans. We work with surface scans and have therefore developed a simple way of estimating layer thicknesses. We use scattering properties...... based on measurements reported in the optics literature, and we compare rendered results qualitatively to images of ceramic teeth created by denturists....

  1. Restoration of primary anterior teeth: review of the literature.

    Science.gov (United States)

    Lee, Jacob K

    2002-01-01

    This paper reviews the published data on restorations of primary anterior teeth. The discussion includes Class III restorations, Class V restorations, various forms of full coronal restorations, atraumatic restorative technique (ART) and recommendations for future research.

  2. Chediak-Higashi syndrome and premature exfoliation of primary teeth.

    Science.gov (United States)

    Rezende, Karla Mayra; Canela, Alfredo Hiram Carrillo; Ortega, Adriana Oliveira Lira; Tintel, Claudia; Bönecker, Marcelo

    2013-01-01

    The Chediak-Higashi syndrome (CHS) is a rare hereditary fatal disease, if not treated. These changes are associated with various diseases and syndromes that mainly cause periodontal disease and thus the premature loss of teeth. This paper describes the monitoring of premature loss of primary teeth that began when the child was 5 years old. On presentation his teeth were mobile and there was a history of gingival bleeding. Panoramic radiography revealed generalized and severe bone loss, and the teeth showed no bony support enough for their stability. Blood test was ordered to assess the overall health of the child and giant cells with cytoplasmic granules were found, confirming the diagnosis of CHS. The management of periodontal disease focused on the control of infection and bacterial plaque by mechanical and chemical methods.

  3. Premature exfoliation of teeth in childhood and adolescence.

    Science.gov (United States)

    Hartsfield, J K

    1994-01-01

    Although the premature loss of primary teeth in conjunction with early eruption may be of no clinical significance, the loss of primary or permanent teeth in the absence of trauma should not be overlooked by the clinician. Premature loss of teeth associated with systemic disease usually results from some change in the immune system or connective tissue. This chapter presented some conditions associated with loosening and/or premature loss of teeth that may be encountered in children and adolescents. The most common of these conditions appear to be hypophosphatasia and early-onset periodontitis. Other less common conditions were described to aid in forming a differential diagnosis. Other diseases that may manifest with severe oral infection, such as Wiskott-Aldrich syndrome, diabetes mellitus, or herpes zoster, could result in early tooth loss.

  4. Association between maxillary sinus pathologies and healthy teeth

    National Research Council Canada - National Science Library

    Roque-Torres, Gina D; Ramirez-Sotelo, Laura Ricardina; Vaz, Sergio Lins de Azevedo; Bóscolo, Solange Maria de Almeida de; Bóscolo, Frab Norberto

    2016-01-01

    The proximity of the roots to the maxillary sinus can create a variety of risks. To evaluate the relationship between the roots of healthy teeth and the maxillary sinus, as well as the occurrence of sinus pathologies...

  5. Knowledge and Practice of Pulp Therapy in Deciduous Teeth ...

    African Journals Online (AJOL)

    Annals of Medical and Health Sciences Research ... of Pulp Therapy in Deciduous Teeth among General Dental Practitioners in Saudi Arabia ... In pulpectomy procedure 44 respondents preferred zinc oxide eugenol as obturation material with ...

  6. Clinical Considerations in Orthodontic Treatment of Teeth with Dentoalveolar Trauma

    OpenAIRE

    2014-01-01

    Dentoalveolar trauma is a very common public health problem. Its influence goes beyond accidents and their impact on teeth, because in the future it becomes a decisive factor if orthodontic treatment is required, because these traumas tend to lead to complications such as root resorption and pulp necrosis. Proper treatment of teeth with a medical history of trauma is essential for successful orthodontic treatment. Los traumas dentoalveolares son un problema de salud pública muy común. La i...

  7. Teeth Grinding: Is Emotional Stability related to Bruxism?

    OpenAIRE

    Sutin, Angelina R; Terracciano, Antonio; Ferrucci, Luigi; Costa, Paul T.

    2010-01-01

    This study examines the association between personality traits and bruxism, the repetitive grinding or clenching of teeth. Community-dwelling participants (N = 470) had a comprehensive oral examination by a dentist and completed a dental history and personality questionnaires. Consistent with the literature on state anxiety and depression as antecedents of bruxism, Neuroticism-related traits were associated with self-reported teeth grinding. These traits were also associated with other oral c...

  8. Teeth in Rare Locations with Rare Complications: An Overview

    OpenAIRE

    Dhingra, Shruti; Gulati, Achal

    2015-01-01

    Ectopic presence of teeth within the dentate region is common in clinical practice. However, the presence of teeth in non-dentate areas such as the nasal cavity or the maxillary sinus is rare. These may remain asymptomatic for years, may be misdiagnosed as foreign bodies, or may present with some serious complications involving the nose and paranasal sinuses. Complications such as nasal obstruction, epistaxis, headaches, rhinolith formation, epiphora, sinusitis and oro-antral fistula have bee...

  9. Triplication in permanent teeth: A rare case report

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    Nidhi Gera

    2017-01-01

    Full Text Available Fusion is an anomaly manifested in both deciduous and permanent dentitions. Triple tooth refers to the union of three separate tooth entities. It can involve the normal dentition or supernumerary teeth. Triplication is rarely encountered in deciduous and permanent dentition with an incidence of 0.02%. The case presented herein describes a rare case of triplication in permanent maxillary incisors and supernumerary teeth in a 15-year-old female.

  10. The longevity of different restorations in primary teeth

    DEFF Research Database (Denmark)

    Qvist, Vibeke; Poulsen, Agneta; Teglers, Poul Thorpen

    2010-01-01

    This paper reviews three published papers and adds results from a fourth study which aimed to determine which restorative material would be the best alternative(s) to amalgam (AM) in primary teeth.......This paper reviews three published papers and adds results from a fourth study which aimed to determine which restorative material would be the best alternative(s) to amalgam (AM) in primary teeth....

  11. What is the Best Root Surface Treatment for Avulsed Teeth?

    OpenAIRE

    Tuna, Elif B.; YAMAN, Duygu; Yamamato, Seiko

    2014-01-01

    Dental avulsion is the most severe type of traumatic tooth injuries since it causes damage to several structures and results in avulsion of the tooth from its socket. Management protocols for avulsed teeth should include management of the pulp and periodontal ligament (PDL) cells in order to improve the long-term prognosis and survival of these teeth. The prognosis of the treatment as well as the survival of an avulsed tooth depends on intrinsic and extrinsic factors, such as the duration of ...

  12. The management of over closured anterior teeth due to attrition

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    Eha Djulaeha

    2009-12-01

    Full Text Available Background: Tooth is the hardest tissue in human body, that can be injured because of attrition process. For old people, denture attrition process is caused by psysiological process relating with the mastication function which also supported by some bad habits such an bruxism, premature contact, and consuming habit of abrasive food. Attrition or abrasion can also be happened with patien’t dentition who does not have teeth subtutition for long time due the lost of their maxillary as well as mandibulary. The pasient will loose their vertical dimension of occlusion, injure, and the lower jaw becomes over closed which is called over closure. Purpose: This article reported the management of over closured anterior teeth due to attrition. Case: a seventy six year old woman patient came to Prosthodontic Clinic in Faculty of Dentistry, Airlangga University, to rehabilitate her upper and lower severe attrited anterior teeth and her posterior teeth. The patient has experienced of wearing acrylic removable mandibular partial denture ten years ago. Unfortunaly, the denture was uncomfortable, and she did not wear it anymore since five years ago. Case management: The severe attrition of anterior teeth with the lost of occlusal vertical dimension can be treated by improving the occlusal vertical dimension gradually. The treatment is then followed by the increasing of the height of the anterior teeth by lengthening the crown teeth of upper jaw with 12 units of span bridge and the acrylic removable partial denture of lower jaw. Conclusion: The severe attrition of anterior teeth with the lost of occlusal vertical dimension can be treated by improving the occlusal vertical dimension gradually, using long span bridge and acrylic removable partial denture.

  13. Is biologic width of anterior and posterior teeth similar?

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    Amir Alireza Rasouli Ghahroudi

    2014-09-01

    Full Text Available The biologic width (BW includes attached epithelial cells and connective tissue attachment complex being very important in the periodontal health during prosthetic treatments as invading this zone can cause bone resorption and gingival recession. The present study investigated biologic width values in the normal periodontium in anterior and posterior teeth. 30 patients that referred from restorative department to periodontics department of Tehran University of medical sciences who need crown lengthening procedure on their teeth with no history of orthodontic, prosthodontic and periodontal treatment were randomly enrolled in this cross-sectional trial. Sulcus depths (SD as well as the distance between free gingival margin and the bone crest (FB of anterior and posterior teeth were measured by UNC-15 probe and compared. periodontium thickness was also assessed. The data were subjected to Student t test. Mean BW in the 43 anterior and 47 posterior teeth was measured and not significantly different (1.4651±0.39 mm vs. 1.6312±0.49 mm was observed; however, BW was significantly more in the teeth with thick periodontium compared to those with thin periodontium (1.703±0.5 vs. 1.408±0.35; P=0.002. BW not only is different in individuals but also could be dissimilar in different teeth and should be calculated independently prior to restorative treatments.

  14. Antioxidant therapy enhances pulpal healing in bleached teeth

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    Adriano Fonseca Lima

    2016-02-01

    Full Text Available Objectives The purpose of this study was to evaluate the histopathological effects of an antioxidant therapy on the pulp tissue of rat teeth exposed to a bleaching gel with 35% hydrogen peroxide. Materials and Methods Forty rats were subjected to oral ingestion by gavage of distilled water (DW or ascorbic acid (AA 90 min before the bleaching therapy. For the bleaching treatment, the agent was applied twice for 5 min each to buccal surfaces of the first right mandibular molars. Then, the animals were sacrificed at 6 hr, 24 hr, 3 day, or 7 day post-bleaching, and the teeth were processed for microscopic evaluation of the pulp tissue. Results At 6 hr, the pulp tissue showed moderate inflammatory reactions in all teeth of both groups. In the DW and AA groups, 100% and 80% of teeth exhibited pulp tissue with significant necrosis and intense tissue disorganization, respectively. At 24 hr, the AA-treated group demonstrated a greater regenerative capability than the DW group, with less intense inflammatory reaction and new odontoblast layer formation in 60% of the teeth. For up to the 7 day period, the areas of pulpal necrosis were replaced by viable connective tissue, and the dentin was underlined by differentiated odontoblast-like cells in most teeth of both groups. Conclusions A slight reduction in initial pulpal damage during post-bleaching was promoted by AA therapy. However, the pulp tissue of AA-treated animals featured faster regenerative potential over time

  15. Comparative analysis of human and bovine teeth: radiographic density

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    Jefferson Luis Oshiro Tanaka

    2008-12-01

    Full Text Available Since bovine teeth have been used as substitutes for human teeth in in vitro dental studies, the aim of this study was to compare the radiographic density of bovine teeth with that of human teeth to evaluate their usability for radiographic studies. Thirty bovine and twenty human teeth were cut transversally in 1 millimeter-thick slices. The slices were X-rayed using a digital radiographic system and an intraoral X-ray machine at 65 kVp and 7 mA. The exposure time (0.08 s and the target-sensor distance (40 cm were standardized for all the radiographs. The radiographic densities of the enamel, coronal dentin and radicular dentin of each slice were obtained separately using the "histogram" tool of Adobe Photoshop 7.0 software. The mean radiographic densities of the enamel, coronal dentin and radicular dentin were calculated by the arithmetic mean of the slices of each tooth. One-way ANOVA demonstrated statistically significant differences for the densities of bovine and human enamel (p 0.05. Based on the results, the authors concluded that: a the radiographic density of bovine enamel is significantly higher than that of human enamel; b the radiodensity of bovine coronal dentin is statistically lower than the radiodensity of human coronal dentin; bovine radicular dentin is also less radiodense than human radicular dentin, although this difference was not statistically significant; c bovine teeth should be used with care in radiographic in vitro studies.

  16. Ankylosed teeth as abutments for maxillary protraction: a case report.

    Science.gov (United States)

    Kokich, V G; Shapiro, P A; Oswald, R; Koskinen-Moffett, L; Clarren, S K

    1985-10-01

    It has been recognized that using the maxillary teeth to deliver extraoral force to the maxilla not only results in sutural remodeling but also periodontal remodeling and tooth movement. In patients with severe maxillomandibular malrelationships, the potential for tooth movement often limits the amount and duration of extraoral force and, consequently, affects the success of treatment. This case report describes a technique to intentionally ankylose deciduous teeth in a patient with severe maxillary retrusion. The ankylosed teeth were used as abutments to deliver an anteriorly directed intermittent extraoral force. After 12 months of treatment, the anterior crossbite was nearly corrected. At that point the ankylosed teeth loosened because of root resorption and the treatment was terminated. Cephalometric superimposition demonstrated that the occlusal correction was the result of anterior maxillary movement with little mandibular growth and no movement of the ankylosed teeth. The results suggest that intentionally ankylosed teeth may be used as abutments for extraoral traction in patients with a severe disturbance in maxillary growth.

  17. MULTIPLE RETAINED TEETH IN MANDIBLE: A Case Report

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    Cvetan Cvetanov

    2010-07-01

    Full Text Available Purpose: The aim of this science report is to show a rare case of multiple impacted teeth at adult patient and our propose clinical approach.Materials and methods: The clinical case is showed from adult man /64-year old/ with multiple impacted teeth (6 impacted teeth in the anterior place on the mandible were not suggestive of any syndrome or metabolic disorder. The extraction of the impacted teeth was made on two stage with piezosurgery unit under local anaesthesia. For prevention of postsurgical complications, as a swelling and prevention of postsurgical resorbtion were used coneshapes from pressure xeno colagen. To base on clinical and radiological examination we will discuss the differential diagnosis and we will offer a clinical approach about decided the case.Result and Conclusion: The incidence of multiple retained teeth by literature research range from 10.9% to 40.4%, most frequently is the retention of the third molars. In the literature most rarely have clinical reports about multiple retained teeth which differ from third molars at adult patients. The rare clinical case we showed is very demonstrative and the medicative approach which we used gave excellent result.

  18. Engineering Macaca fascicularis cytochrome P450 2C20 to reduce animal testing for new drugs.

    Science.gov (United States)

    Rua, Francesco; Sadeghi, Sheila J; Castrignanò, Silvia; Di Nardo, Giovanna; Gilardi, Gianfranco

    2012-12-01

    In order to develop in vitro methods as an alternative to P450 animal testing in the drug discovery process, two main requisites are necessary: 1) gathering of data on animal homologues of the human P450 enzymes, currently very limited, and 2) bypassing the requirement for both the P450 reductase and the expensive cofactor NADPH. In this work, P450 2C20 from Macaca fascicularis, homologue of the human P450 2C8 has been taken as a model system to develop such an alternative in vitro method by two different approaches. In the first approach called "molecular Lego", a soluble self-sufficient chimera was generated by fusing the P450 2C20 domain with the reductase domain of cytochrome P450 BM3 from Bacillus megaterium (P450 2C20/BMR). In the second approach, the need for the redox partner and also NADPH were both obviated by the direct immobilization of the P450 2C20 on glassy carbon and gold electrodes. Both systems were then compared to those obtained from the reconstituted P450 2C20 monooxygenase in presence of the human P450 reductase and NADPH using paclitaxel and amodiaquine, two typical drug substrates of the human P450 2C8. The K(M) values calculated for the 2C20 and 2C20/BMR in solution and for 2C20 immobilized on electrodes modified with gold nanoparticles were 1.9 ± 0.2, 5.9 ± 2.3, 3.0 ± 0.5 μM for paclitaxel and 1.2 ± 0.2, 1.6±0.2 and 1.4 ± 0.2 μM for amodiaquine, respectively. The data obtained not only show that the engineering of M. fascicularis did not affect its catalytic properties but also are consistent with K(M) values measured for the microsomal human P450 2C8 and therefore show the feasibility of developing alternative in vitro animal tests. Copyright © 2012 Elsevier Inc. All rights reserved.

  19. Modes of transmission and genetic diversity of foamy viruses in a Macaca tonkeana colony

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    Saib Ali

    2006-04-01

    Full Text Available Abstract Background Foamy viruses are exogenous complex retroviruses that are highly endemic in several animal species, including monkeys and apes, where they cause persistent infection. Simian foamy viral (SFV infection has been reported in few persons occupationally exposed to non-human primates (NHP in zoos, primate centers and laboratories, and recently in few hunters from central Africa. Most of the epidemiological works performed among NHP populations concern cross-sectional studies without long-term follow-up. Therefore, the exact timing and the modes of transmission of SFVs remain not well known, although sexual and oral transmissions have been suspected. We have conducted a longitudinal study in a free-breeding colony of Macaca tonkeana in order (1 to determine the prevalence of the infection by foamy viruses, (2 to characterize molecularly the viruses infecting such animals, (3 to study their genetic variability overtime by long-term follow-up of several DNA samples in a series of specific animals, and (4 to get new insights concerning the timing and the modes of SFVs primary infection in these monkeys by combining serology and molecular means, as well as studies of familial structures and long-term behavioral observations. Results/conclusion We first demonstrated that this colony was highly endemic for SFVs, with a clear increase of seroprevalence with age. Only 4.7% of immatures, and 43,7% of sub-adults were found seropositive, while 89.5% of adults exhibited antibodies directed against SFV. We further showed that 6 different strains of foamy viruses (exhibiting a very low intra-strain and overtime genetic variability in the integrase gene are circulating within this group. This suggests a possible infection by different strains within an animal. Lastly, we provide strong evidence that foamy viruses are mostly acquired through severe bites, mainly in sub-adults or young adults. Most cases of seroconversion occur after 7 years of age

  20. Experience-based human perception of facial expressions in Barbary macaques (Macaca sylvanus

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    Laëtitia Maréchal

    2017-06-01

    Full Text Available Background Facial expressions convey key cues of human emotions, and may also be important for interspecies interactions. The universality hypothesis suggests that six basic emotions (anger, disgust, fear, happiness, sadness, and surprise should be expressed by similar facial expressions in close phylogenetic species such as humans and nonhuman primates. However, some facial expressions have been shown to differ in meaning between humans and nonhuman primates like macaques. This ambiguity in signalling emotion can lead to an increased risk of aggression and injuries for both humans and animals. This raises serious concerns for activities such as wildlife tourism where humans closely interact with wild animals. Understanding what factors (i.e., experience and type of emotion affect ability to recognise emotional state of nonhuman primates, based on their facial expressions, can enable us to test the validity of the universality hypothesis, as well as reduce the risk of aggression and potential injuries in wildlife tourism. Methods The present study investigated whether different levels of experience of Barbary macaques, Macaca sylvanus, affect the ability to correctly assess different facial expressions related to aggressive, distressed, friendly or neutral states, using an online questionnaire. Participants’ level of experience was defined as either: (1 naïve: never worked with nonhuman primates and never or rarely encountered live Barbary macaques; (2 exposed: shown pictures of the different Barbary macaques’ facial expressions along with the description and the corresponding emotion prior to undertaking the questionnaire; (3 expert: worked with Barbary macaques for at least two months. Results Experience with Barbary macaques was associated with better performance in judging their emotional state. Simple exposure to pictures of macaques’ facial expressions improved the ability of inexperienced participants to better discriminate neutral

  1. Experience-based human perception of facial expressions in Barbary macaques (Macaca sylvanus).

    Science.gov (United States)

    Maréchal, Laëtitia; Levy, Xandria; Meints, Kerstin; Majolo, Bonaventura

    2017-01-01

    Facial expressions convey key cues of human emotions, and may also be important for interspecies interactions. The universality hypothesis suggests that six basic emotions (anger, disgust, fear, happiness, sadness, and surprise) should be expressed by similar facial expressions in close phylogenetic species such as humans and nonhuman primates. However, some facial expressions have been shown to differ in meaning between humans and nonhuman primates like macaques. This ambiguity in signalling emotion can lead to an increased risk of aggression and injuries for both humans and animals. This raises serious concerns for activities such as wildlife tourism where humans closely interact with wild animals. Understanding what factors (i.e., experience and type of emotion) affect ability to recognise emotional state of nonhuman primates, based on their facial expressions, can enable us to test the validity of the universality hypothesis, as well as reduce the risk of aggression and potential injuries in wildlife tourism. The present study investigated whether different levels of experience of Barbary macaques, Macaca sylvanus, affect the ability to correctly assess different facial expressions related to aggressive, distressed, friendly or neutral states, using an online questionnaire. Participants' level of experience was defined as either: (1) naïve: never worked with nonhuman primates and never or rarely encountered live Barbary macaques; (2) exposed: shown pictures of the different Barbary macaques' facial expressions along with the description and the corresponding emotion prior to undertaking the questionnaire; (3) expert: worked with Barbary macaques for at least two months. Experience with Barbary macaques was associated with better performance in judging their emotional state. Simple exposure to pictures of macaques' facial expressions improved the ability of inexperienced participants to better discriminate neutral and distressed faces, and a trend was found for

  2. Mitochondrial DNA variation in Chinese and Indian rhesus macaques (Macaca mulatta).

    Science.gov (United States)

    Smith, David Glenn; McDonough, John

    2005-01-01

    DNA was extracted from the buffy coats or serum of 212 rhesus macaques (Macaca mulatta) sampled throughout the species' geographic range. An 835 base pair (bp) fragment of mitochondrial DNA (mtDNA) was amplified from each sample, sequenced, aligned, and used to estimate genetic distances from which phylogenetic trees were constructed. A tree that included sequences from rhesus macaques whose exact origins in China are known was used to determine the regional origin of clusters of haplotypes, or haplogroups, defined by the trees. Indian rhesus sequences formed one large homogeneous haplogroup with very low levels of nucleotide diversity and no geographic structure, and a second much smaller haplogroup apparently derived from Burma. The sequences from Burma and eastern and western China were quite divergent from those in the major haplogroup of India. Each of these sequences formed separate clusters of haplotypes that exhibited far greater nucleotide diversity and/or population structure. Correspondingly, sequences from Indian rhesus macaques that are considered to represent different subspecies (based on morphological differences) were intermingled in the tree, while those from China reflected some, but not all, aspects of subspecific taxonomy. Regional variation contributed 72% toward the paired differences between sequences in an analysis of molecular variance (AMOVA), and the average differences between the populations of eastern and western China were also statistically significant. These results suggest that Indian and Chinese rhesus macaques were reproductively isolated during most, if not all, of the Pleistocene, during which time Indian rhesus macaques experienced a severe genetic bottleneck, and that some gene flow westward into India was subsequently reestablished. Samples from breeding centers in three different provinces of China included sequences from rhesus macaques that originated in both eastern (or southern) and western China, confirming anecdotal

  3. Structure, attachment, replacement and growth of teeth in bluefish, Pomatomus saltatrix (Linnaeus, 1776), a teleost with deeply socketed teeth.

    Science.gov (United States)

    Bemis, William E; Giuliano, Anne; McGuire, Betty

    2005-01-01

    Tooth replacement poses many questions about development, pattern formation, tooth attachment mechanisms, functional morphology and the evolution of vertebrate dentitions. Although most vertebrate species have polyphyodont dentitions, detailed knowledge of tooth structure and replacement is poor for most groups, particularly actinopterygians. We examined the oral dentition of the bluefish, Pomatomus saltatrix, a pelagic and coastal marine predator, using a sample of 50 individuals. The oral teeth are located on the dentary and premaxillary bones, and we scored each tooth locus in the dentary and premaxillary bones using a four-part functional classification: absent (A), incoming (I), functional (F=fully ankylosed) or eroding (E). The homodont oral teeth of Pomatomus are sharp, deeply socketed and firmly ankylosed to the bone of attachment. Replacement is intraosseus and occurs in alternate tooth loci with long waves of replacement passing from rear to front. The much higher percentage of functional as opposed to eroding teeth suggests that replacement rates are low but that individual teeth are quickly lost once erosion begins. Tooth number increases ontogenetically, ranging from 15-31 dentary teeth and 15-39 premaxillary teeth in the sample studied. Teeth increase in size with every replacement cycle. Remodeling of the attachment bone occurs continuously to accommodate growth. New tooth germs originate from a discontinuous dental lamina and migrate from the lingual (dentary) or labial (premaxillary) epithelium through pores in the bone of attachment into the resorption spaces beneath the existing teeth. Pomatomus shares unique aspects of tooth replacement with barracudas and other scombroids and this supports the interpretation that Pomatomus is more closely related to scombroids than to carangoids.

  4. Efeito do CO2 e etileno no período de dormência de minitubérculos de batata cv. Macaca Effect of CO2 and ethylene on the dormancy period of potato cv. Macaca minitubers

    Directory of Open Access Journals (Sweden)

    Dilson Antônio Bisognin

    2007-06-01

    Full Text Available Avaliou-se o efeito do CO2 e etileno no período de dormência de minitubérculos de batata da cultivar Macaca produzidos em telado durante duas safras. Imediatamente após a colheita, os minitubérculos foram submetidos aos tratamentos de abafamento com etileno (1000 mL L-1 por 72 h; CO2 (20% por 72 h; carbureto de cálcio (200 g m-3 por 72 h; e 1-metilciclopropeno (1-MCP (1mL L-1 por 24 h (apenas na safrinha; e imersão em solução de ethephon (840 mg L-1 por 5 s. A testemunha não recebeu nenhum tratamento. O delineamento experimental foi um fatorial (safras x tratamentos no inteiramente casualizado, com quatro repetições de 15 minitubérculos. Em intervalos semanais foram avaliadas a respiração e a produção de etileno. A cada 15 dias avaliou-se o número de brotos e a percentagem de tubérculos brotados, calculando-se a área abaixo da curva de progressão. Os minitubérculos produzidos durante a safra, comparados com os da safrinha, apresentaram menor período de dormência e aumentaram a taxa respiratória durante o período de armazenamento, claramente relacionados com a brotação dos minitubérculos. O CO2 e etileno não promoveram o encurtamento, enquanto que o 1-MCP prolongou o período de dormência de minitubérculos de batata cv. Macaca.The effect of CO2 and ethylene treatments were evaluated on the dormancy period of 'Macaca' minitubers produced in greenhouse during two growing seasons. Minitubers were treated soon after harvesting. The treatments were suffocation with ethylene (1000 mL L-1 during 72 h; CO2 (20 % during 72 h; calcium carburet (200 g m-3 during 72 h; and 1-methylcyclopropene (1-MCP (1 mL L-1 during 24 h (only for second season; and immersion with 2-cloroetil fosfonic acid (840 mg L-1 during 5 s. Control minitubers did not receive any treatment. The experiment was a factorial (seasons x treatments in a randomized design, with four replications of 15 minitubers. Respiration and ethylene production were

  5. Late Developing Supernumeraries in a Case of Nonsyndromic Multiple Supernumerary Teeth

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    Mine Bozkurt

    2015-01-01

    Full Text Available Objective. This case report presents 3-year follow-up of a case of nonsyndromic multiple supernumerary teeth (NSMST with 11 supernumerary teeth, 2 of which showed subsequent formation. Case Report. A 10-year-old girl was referred to the dental clinic with the chief complaint of delayed eruption. Radiographic examination showed 9 retained supernumerary teeth. The treatment plan consisted of extraction of the supernumerary teeth and associated primary teeth in order to allow the permanent teeth to erupt. After 2 years of follow-up, 2 additional supernumerary teeth were observed. Conclusion. Regular follow-up for late forming supernumeraries is crucial for NSMST cases.

  6. The effects of racemization rate for age estimation of pink teeth.

    Science.gov (United States)

    Sakuma, Ayaka; Saitoh, Hisako; Ishii, Namiko; Iwase, Hirotaro

    2015-03-01

    Pink teeth is thought to result from the seepage of hemoglobin caused by dental pulp decomposition. We investigated whether racemization can be applied for age estimation in cases of pink teeth where the whole tooth is used. The pink teeth used were three cases and the normal teeth for control were five mandibular canines of known age. Age of the pink teeth was calculated on the basis of regression formula obtained from the five control teeth. Only a slight error was noted between the actual and estimated ages of the pink teeth (R(2) = 0.980, r = 0.990): Cases 1-3 actually aged 23, 53, and 59 years were estimated to be 26, 52, and 60 years. Based on our results of testing pink teeth of known age, we suggest that racemization techniques allow for the age estimation of pink teeth using the same methods for normally colored teeth.

  7. Prevalence of teeth number anomalies in orthodontic patients.

    Science.gov (United States)

    Trakinienė, Giedrė; Ryliškytė, Monika; Kiaušaitė, Aurelija

    2013-01-01

    The purpose of this study was to determine if the prevalence of teeth number anomalies (TNA) is more frequent in orthodontic patients than in common population and what is TNA clinical manifestation. The records of 824 orthodontic patients (average age 15.22 years) from Orthodontic Clinic of Lithuanian University of Health Sciences were analyzed. The radiographs were analyzed by trained observer who followed a pre-established protocol: general observation of the teeth including third molar, followed by a systematic analysis of the erupted and unerupted teeth number in each quadrant. Descriptive statistics were performed for the study variables. A chi-square test was used to determine the difference in the prevalence of hypodontia between the genders. A value of P0.05). More frequently teeth were missing in the lower jaw: in the upper jaw - 10.3%, in the lower - 12.5% without statisticaly significant diference. Unilateral occurrence of dental agenesis was 1.5 times more common than bilateral occurrence. If more than one tooth was missing, usually other missing tooth was in the same group and in the same jaw. The upper and lower third molars were the most frequently missing teeth, followed by the mandibular second premolar. The prevalence of hyperdontia was 0.85 percent. Mesiodens was the most frequently found supernumerary tooth. It was found, that 17.96% of orthodontic patients had teeth number anomalies. The upper and lower third molars were the most frequently missing teeth, followed by the mandibular second premolar. Hypodontia occurred more frequently than hyperdontia. Mesiodens was the most frequently found supernumerary tooth. The results confirm that TNA are more often found in orthodontic patients and these patients should be treated with multidisciplinary approach.

  8. Late Developing Supernumeraries in a Case of Nonsyndromic Multiple Supernumerary Teeth

    OpenAIRE

    Mine Bozkurt; Tugba Bezgin; Ayşegül Tüzüner Öncül; Rukiye Göçer; Şaziye Sarı

    2015-01-01

    Objective. This case report presents 3-year follow-up of a case of nonsyndromic multiple supernumerary teeth (NSMST) with 11 supernumerary teeth, 2 of which showed subsequent formation. Case Report. A 10-year-old girl was referred to the dental clinic with the chief complaint of delayed eruption. Radiographic examination showed 9 retained supernumerary teeth. The treatment plan consisted of extraction of the supernumerary teeth and associated primary teeth in order to allow the permanent tee...

  9. Contrasting the edge- and surface-based theories of object recognition: behavioral evidence from macaques (Macaca mulatta).

    Science.gov (United States)

    Parron, Carole; Washburn, David

    2010-01-01

    This study assessed the contribution of edge and surface cues on object representation in macaques (Macaca mulatta). In Experiments 1 and 2, 5 macaques were trained to discriminate 4 simple volumetric objects (geons) and were subsequently tested for their ability to recognize line drawings, silhouettes, and light changes of these geons. Performance was above chance in all test conditions and was similarly high for the line drawings and silhouettes of geons, suggesting the use of the outline shape to recognize the original objects. In addition, transfer for the geons seen under new lighting was greater than for the other stimuli, stressing the importance of the shading information. Experiment 3, using geons filled with new textures, showed that a radical change in the surface cues does not prevent object recognition. It is concluded that these findings support a surface-based theory of object recognition in macaques, although it does not exclude the contribution of edge cues, especially when surface details are not available.

  10. Land use in semi-free ranging Tonkean macaques Macaca tonkeana depends on environmental conditions: A geographical information system approach

    Institute of Scientific and Technical Information of China (English)

    Cédric SUEUR; Paul SALZE; Christiane WEBER; Odile PETIT

    2011-01-01

    Wild animals use their habitat according to ecological pressures such as predaton, resource availability or temperature, yet little is known about how individuals use their environment in semi free-ranging conditions. We assessed whether a semi-free ranging group of Tonkean macaques Macaca tonkeana used its wooded parkland in a heterogeneous way. GIS and GPS were used to determine whether individuals adjusted their behaviors according to variation in environmental constraints over time of day and the course of a year. We demonstrated that social and resting activities occurred in high altitude areas and areas with a high density of bushes, whereas the group foraged in areas where the density of bushes and grass was low. In general, the animals used areas exposed to the sun that were not on a slope. Semi-free ranging Tonkean macaques seemed to behave like their wild counterparts in terms of activity budget, land use per activity and thermoregulation.

  11. Evidence of Placentophagia and Mother-Infant Cannibalism in Free-Ranging Macaca mulatta tcheliensis in Mount Taihangshan, Jiyuan, China.

    Science.gov (United States)

    Tian, Jundong; Zhang, Shiqiang; Guo, Yongman; Garber, Paul A; Guo, Weijie; Kuang, San''ao; Lu, Jiqi

    2016-01-01

    Placentophagia or the consumption of the afterbirth is reported in many primate species, whereas cannibalism is a relatively rare event. Based on our field observations over the course of 3 years, we present evidence of placentophagia and mother-infant cannibalism in a free-ranging population of the Taihangshan macaque, Macaca mulatta tcheliensis, in the Mt. Taihangshan area, Jiyuan, Henan, China. We documented 1 case in which a mother consumed the afterbirth of her infant. In a second instance, we observed a fresh placenta discarded on the ground by an unknown individual. We also present a description of the first documented instance of mother-infant cannibalism in the same group of free-ranging rhesus macaques. © 2017 S. Karger AG, Basel.

  12. Locally infiltrative ameloblastic fibroma in a rhesus macaque (Macaca mulatta) with characterizations of its proliferating activity and biological behavior.

    Science.gov (United States)

    Liu, David X; Doyle, Lara A; Bouljihad, Mostafa T; Didier, Peter J; Gilbert, Margaret H; Wang, Xiaolei; Pahar, Bapi; Bohm, Rudolf P; Veazey, Ronald S; Lackner, Andrew A

    2012-05-01

    An 8-year-old male rhesus macaque (Macaca mulatta) presented with unilateral enlargement of the left mandible. Radiographs revealed a marked expansion of the left mandible with a multilocular radiolucent mass with abundant osteolysis. The mass was grossly firm, fleshy, and gelatinous on the cut surface. Histologically, the mass was locally infiltrative and composed of neoplastic epithelial and mesenchymal components that stained positive for cytokeratin and vimentin, respectively. Occasional densely spherical condensations of fibroblasts resembling the cap stage of odontogenesis were present in the mesenchyma. Immunohistochemical staining with Ki-67, S-100, and CD34 indicated that both epithelial and mesenchymal components of the neoplasm had low proliferation. Alcian blue, periodic acid-Schiff, and trichrome stains showed an immature stromal component with no collagen formation. Based on the clinical, histologic, and immunophenotypic features, the tumor was identified as a locally infiltrative ameloblastic fibroma.

  13. Comparison of noncontact infrared thermometry and 3 commercial subcutaneous temperature transponding microchips with rectal thermometry in rhesus macaques (Macaca mulatta).

    Science.gov (United States)

    Brunell, Marla K

    2012-07-01

    This study compared a noncontact infrared laser thermometer and 3 different brands of subcutaneous temperature transponding microchips with rectal thermometry in 50 rhesus macaques (Macaca mulatta). The data were analyzed by using intraclass correlation coefficients and limits of agreement. In addition, the technical capabilities and practicality of the thermometers in the clinical setting were reviewed. None of the alternative techniques investigated was equivalent to rectal thermometry in rhesus macaques. Temperatures obtained by using microchips had higher correlation and agreed more closely with rectal temperatures than did those obtained by the noncontact infrared method. However, transponding microchips did not yield consistent results. Due to difficulty in positioning nonsedated macaques in their homecage, subcutaneous microchips were not practical in the clinical setting. Furthermore, pair-housed macaques may be able to break or remove microchips from their cagemates.

  14. Pathogenic infection of Macaca nemestrina with a CCR5-tropic subtype-C simian-human immunodeficiency virus

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    Song Ruijiang

    2009-07-01

    Full Text Available Abstract Background Although pig-tailed macaques (Macaca nemestrina have been used in AIDS research for years, less is known about the early immunopathogenic events in this species, as compared to rhesus macaques (Macaca mulatta. Similarly, the events in early infection are well-characterized for simian immunodeficiency viruses (SIV, but less so for chimeric simian-human immunodeficiency viruses (SHIV, although the latter have been widely used in HIV vaccine studies. Here, we report the consequences of intrarectal infection with a CCR5-tropic clade C SHIV-1157ipd3N4 in pig-tailed macaques. Results Plasma and cell-associated virus was detectable in peripheral blood and intestinal tissues of all four pig-tailed macaques following intrarectal inoculation with SHIV-1157ipd3N4. We also observed a rapid and irreversible loss of CD4+ T cells at multiple mucosal sites, resulting in a marked decrease of CD4:CD8 T cell ratios 0.5–4 weeks after inoculation. This depletion targeted subsets of CD4+ T cells expressing the CCR5 coreceptor and having a CD28-CD95+ effector memory phenotype, consistent with the R5-tropism of SHIV-1157ipd3N4. All three animals that were studied beyond the acute phase seroconverted as early as week 4, with two developing cross-clade neutralizing antibody responses by week 24. These two animals also demonstrated persistent plasma viremia for >48 weeks. One of these animals developed AIDS, as shown by peripheral blood CD4+ T-cell depletion starting at 20 weeks post inoculation. Conclusion These findings indicate that SHIV-1157ipd3N4-induced pathogenesis in pig-tailed macaques followed a similar course as SIV-infected rhesus macaques. Thus, R5 SHIV-C-infection of pig-tailed macaques could provide a useful and relevant model for AIDS vaccine and pathogenesis research.

  15. Mimetic Muscles in a Despotic Macaque (Macaca mulatta) Differ from Those in a Closely Related Tolerant Macaque (M. nigra).

    Science.gov (United States)

    Burrows, Anne M; Waller, Bridget M; Micheletta, Jérôme

    2016-10-01

    Facial displays (or expressions) are a primary means of visual communication among conspecifics in many mammalian orders. Macaques are an ideal model among primates for investigating the co-evolution of facial musculature, facial displays, and social group size/behavior under the umbrella of "ecomorphology". While all macaque species share some social behaviors, dietary, and ecological parameters, they display a range of social dominance styles from despotic to tolerant. A previous study found a larger repertoire of facial displays in tolerant macaque species relative to despotic species. The present study was designed to further explore this finding by comparing the gross morphological features of mimetic muscles between the Sulawesi macaque (Macaca nigra), a tolerant species, and the rhesus macaque (M. mulatta), a despotic species. Five adult M. nigra heads were dissected and mimetic musculature was compared to those from M. mulatta. Results showed that there was general similarity in muscle presence/absence between the species as well as muscle form except for musculature around the external ear. M. mulatta had more musculature around the external ear than M. nigra. In addition, M. nigra lacked a zygomaticus minor while M. mulatta is reported to have one. These morphological differences match behavioral observations documenting a limited range of ear movements used by M. nigra during facial displays. Future studies focusing on a wider phylogenetic range of macaques with varying dominance styles may further elucidate the roles of phylogeny, ecology, and social variables in the evolution of mimetic muscles within Macaca Anat Rec, 299:1317-1324, 2016. © 2016 Wiley Periodicals, Inc.

  16. Near-IR imaging of cracks in teeth

    Science.gov (United States)

    Fried, William A.; Simon, Jacob C.; Lucas, Seth; Chan, Kenneth H.; Darling, Cynthia L.; Staninec, Michal; Fried, Daniel

    2014-02-01

    Dental enamel is highly transparent at near-IR wavelengths and several studies have shown that these wavelengths are well suited for optical transillumination for the detection and imaging of tooth decay. We hypothesize that these wavelengths are also well suited for imaging cracks in teeth. Extracted teeth with suspected cracks were imaged at several wavelengths in the near-IR from 1300-1700-nm. Extracted teeth were also examined with optical coherence tomography to confirm the existence of suspected cracks. Several teeth of volunteers were also imaged in vivo at 1300-nm to demonstrate clinical potential. In addition we induced cracks in teeth using a carbon dioxide laser and imaged crack formation and propagation in real time using near-IR transillumination. Cracks were clearly visible using near-IR imaging at 1300-nm in both in vitro and in vivo images. Cracks and fractures also interfered with light propagation in the tooth aiding in crack identification and assessment of depth and severity.

  17. CRITICAL ANALYSIS OF ARTIFICIAL TEETH FOR ENDODONTIC TEACHING

    Science.gov (United States)

    Nassri, Maria Renata Giazzi; Carlik, Jaime; da Silva, Camila Roberta Nepomuceno; Okagawa, Renata Elisa; Lin, Suzy

    2008-01-01

    The purpose of this study was to evaluate the use of artificial teeth for endodontic teaching. A questionnaire was prepared and submitted to 18 professors of Endodontics from different Brazilian universities to evaluate the following features of five cloudy resin artificial teeth: internal and external anatomy; coronal chambers regarding their size, shape and canal path; root canal regarding their size, shape and position; fulfillment of the pulp chamber and root canals by considering the texture, quantity, color, and ease of handling; resin hardness and visualization of the radiographic image. The results presented favorable opinions, in terms of internal and external anatomy, coronal pulp chambers and root canal and handling and radiographic imaging. The contents of the pulp space and hardness of the teeth were considered satisfactory. The average grade assigned to the artificial tooth quality was 8.4, in a 0-10 scale. In conclusion, the artificial teeth have potential to replace the natural teeth in endodontic teaching; however, improvements are still necessary to reach a better quality model. PMID:19089288

  18. Correlation between three color coordinates of human teeth.

    Science.gov (United States)

    Lee, Yong-Keun

    2014-11-01

    The objective was to determine whether there were significant correlations in the three color coordinates within each of two color coordinate systems, such as the Commission Internationale de l’Eclairage (CIE) L*a*b* system, and the lightness, chroma, and hue angle system, of human vital teeth. The color of six maxillary and six mandibular anterior teeth was measured by the Shade Vision System. Pearson correlations between each pair of the color coordinates were determined (α=0.01 ). The influence of two color coordinates on the other color coordinate was determined with a multiple regression analysis (α=0.01 ). Based on correlation analyses, all the color coordinate pairs showed significant correlations except for the chroma and hue angle pair. The CIE L* was negatively correlated with the CIE a*,b*, and chroma, but positively correlated with the hue angle. The CIE a* was positively correlated with the CIE b* and chroma. Tooth color coordinates were correlated each other. Lighter teeth were less chromatic both in the CIE a* and b* coordinates. Therefore, it was postulated that the three color coordinates of human teeth were harmonized within certain color attribute ranges, and a lack of correlations in these coordinates might indicate external/internal discolorations and/or anomalies of teeth.

  19. Influence of Different Rotor Teeth Shapes on the Performance of Flux Switching Permanent Magnet Machines Used for Electric Vehicles

    OpenAIRE

    Jing Zhao; Yashuang Yan; Bin Li; Xiangdong Liu; Zhen Chen

    2014-01-01

    This paper investigated a 12-slot/11-pole flux switching permanent magnet (FSPM) machine used for electric vehicles (EVs). Five novel rotor teeth shapes are proposed and researched to reduce the cogging torque and torque ripple of the FSPM machine. These rotor teeth shapes are notched teeth, stepped teeth, eccentric teeth, combination of notched and stepped teeth, and combination of notched and eccentric teeth. They are applied on the rotor and optimized, respectively. The influences of diffe...

  20. Overlay removable denture for treatment of worn teeth.

    Science.gov (United States)

    Beyth, Nurit; Tamari, Israel; Buller Sharon, Anat

    2014-01-01

    Rehabilitation of partially edentulous patients with excessively worn dentitions can be challenging. Factors including medical history as well as the cost of the treatment and patient wishes for simpler approaches must be considered. This manuscript describes the use of an overlay partial denture to treat patients with excessive wear of the maxillary teeth. We describe a technique to restore severely worn teeth using heat-cured acrylic as part of a partial or full denture. Minimal preparations of the teeth are required, and the restoration provides protection from further wear, and stabilizes the occlusion. This solution was functionally and esthetically suitable to the patients. The technique can be used in medically complex patients where extractions are contraindicated, such as post radiation therapy or bisphosphonate treatment.

  1. Optimizing the Esthetics of peg-shaped teeth

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    Fabia Danielle Sales da Cunha Medeiros e Silva

    2008-01-01

    Full Text Available In modern esthetic dentistry, recontouring peg-shaped teeth present the option of a technique for obtaining a harmonious smile. In thiscontext, the advancement of direct dental materials, such as resin composites and adhesive systems, allows this procedure to be performedsimply and efficiently, when compared with other available techniques. Thus, the aim of this report is to present a clinical case with an esthetic solution in peg-shaped lateral incisors (12 and 22. Initially, it was opted first to perform dental bleaching with a home bleaching gel (16% carbamide peroxide associated with an acetate mold duly made for this purpose. The peg-shaped teeth were recontoured with a microhybrid resin composite (shade EA1 and DA1 with the aid of a platinum guide in silicone, obtained after diagnostic waxing on the plaster model. It was concluded that the association of esthetic procedures is of the utmost importance for obtaining good looking, aligned and harmonious teeth.

  2. Dentinogenesis imperfecta type II: ultrastructure of teeth in sagittal sections.

    Science.gov (United States)

    Wieczorek, Aneta; Loster, Jolanta

    2013-01-01

    The morphological abnormalities of the teeth of patients affected by dentinogenesis imperfecta type 2 (DI-II) may underlie the difficulties with the clinical restoration of such teeth. We therefore performed a scanning electron microscopy (SEM) study of four permanent first mandibular molars of four DI-II patients with periapical pathosis. The teeth were prepared for SEM evaluation by standard methods. In the crown, the enamel presented a highly irregular surface with a number of cracks and crevices. In some places, only granular remains of the enamel were found, while in other parts of the crown, the enamel was absent. SEM examination revealed the structural changes responsible for the lower enamel's hardness and resistance to attrition, and for tooth wear, while the structural changes in the dentin may explain the failure of some adhesive restorative materials. This SEM study thus revealed structural defects which underlie the problems of attrition and restoration loss found in patients with this genetic dental condition.

  3. Fracture resistance of teeth restored with dentin-bonded crowns.

    Science.gov (United States)

    Burke, F J; Watts, D C

    1994-05-01

    While dentin-bonded crowns may hold esthetic advantages over metal-ceramic restorations, and minimal tooth preparation may also be appropriate, resistance to fracture of the restored unit is an important consideration. Dentin-bonded crowns were placed on standardized preparations in two groups of 10 maxillary premolar teeth in vitro. The preparations differed only in degree of taper. The restored specimens were subjected to compressive loading at 1 mm/min from a steel bar placed along the midline fissure. Mean fracture loads of 0.77 kN (6-degree taper) and 0.71 kN (8-degree taper) were recorded for the groups of prepared teeth, and a mean fracture load of 0.97 kN was obtained for a group of unprepared controls. Statistical analysis indicated that there was no significant difference between the fracture load of the 6-degree taper group and that of the sound control teeth.

  4. Teeth in Rare Locations with Rare Complications: An Overview.

    Science.gov (United States)

    Dhingra, Shruti; Gulati, Achal

    2015-12-01

    Ectopic presence of teeth within the dentate region is common in clinical practice. However, the presence of teeth in non-dentate areas such as the nasal cavity or the maxillary sinus is rare. These may remain asymptomatic for years, may be misdiagnosed as foreign bodies, or may present with some serious complications involving the nose and paranasal sinuses. Complications such as nasal obstruction, epistaxis, headaches, rhinolith formation, epiphora, sinusitis and oro-antral fistula have been well described in literature, however, very few cases of antro-cutaneous fistulas have been reported. We discuss three cases of ectopic eruptions of teeth, all occurring in children. The clinical and radiographic findings of the cases, possible etiology, complication, diagnosis and treatment are discussed.

  5. Clinical management of supernumerary teeth: A report of two cases

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    Mittal M

    2010-09-01

    Full Text Available Supernumerary tooth may closely resemble the teeth of the group to which it belongs, i.e. molars, premolars or anterior teeth, or it may bear little resemblancein size or shape to which it is associated. Many complications can be associated with supernumeraries, like impaction, delayed eruption or ectopic eruption of adjacent teeth, crowding, development of median diastema and eruption into floor of the nasal cavity. This may also cause the formation of follicular cysts with significant bone destruction. Early intervention to remove it is usually required to obtain reasonable alignment and occlusal relationship. This article will present the clinical management of an (i impacted supernumerary tooth impeding the eruption of maxillary central incisor and (ii erupted supernumerary tooth with midline diastema.

  6. The optimal design of involute gear teeth with unequal addenda

    Science.gov (United States)

    Savage, M.; Coy, J. J.; Townsend, D. P.

    1982-01-01

    The design of a gear mesh is treated with the objective of minimizing the gear size for a given gear ratio, pinion torque, pressure angle, and allowable tooth lengths. Tooth strengths considered include scoring, pitting fatigue, and bending fatigue. Kinematic involute interference is avoided. The design variation on standard spur gear teeth called the long and short addendum system, is considered. In this system the mesh center distance and pressure angle are maintained as is the ability to manufacture the teeth with standard tooling. However, the pinion and gear tooth proportions are altered in order to obtain fewer teeth numbers for the same ratio as standard gears without kinematic involute interference. The effect of this nonstandard gearing geometry with on tooth strengths and gear mesh size are studied. For a 2:1 gearing ratio, the optimal nonstandard gear design is compared with the optimal standard gear design.

  7. Aspiration of two permanent teeth during maxillofacial injuries.

    Science.gov (United States)

    Xiao, Wen-lin; Zhang, Dai-zun; Wang, Yan-hui

    2009-03-01

    Aspiration of a tooth in maxillofacial injuries is a known complication necessitating prompt recognition and early treatment to minimize potentially serious and, sometimes, even fatal consequences. Here, we report a rare and unusual case in its presentation, the patient having aspirated 2 permanent teeth after maxillofacial, cervical vertebrae, and thoracic region crush injuries due to a motor vehicle accident. The diagnosis of teeth aspiration was delayed until 2 weeks after the event. An aspirated anterior tooth was expectorated by the patient himself, and the other aspirated anterior tooth was removed by flexible bronchoscopy. The paper also emphasizes that clinicians must be aware of dental injury resulting from maxillofacial injuries and account for all teeth as part of their evaluation, keeping an open mind as to where a missing tooth might be located. A rapid diagnosis depends on high clinical suspicion, clinical signs, and radiologic findings.

  8. Analysis of cracks generated in the spinning-mandrel teeth

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    M. Haghshenas

    2014-10-01

    Full Text Available The spinning process, using a splined mandrel, is always prone to premature failure of the splined mandrels. Such a failure is thought to be related to the magnitude of the forming forces exerted on the mandrel by the forming rollers during the spinning process. In the present paper, the characteristic of corner cracks in the mandrel teeth (made of S7 tool steel of a spinning process has been investigated. The rotational speed of the mandrel is about 300 rpm during spinning process and the sheet metal (i.e. AISI 1020 is in contact with mandrel teeth to get the mandrel shape at the end of process. During this process, the mandrel teeth eventually break away. Fractography analyses using scanning electron microscopy (SEM clearly confirm “fatigue” as being the main reason for the failure.

  9. Rotary endodontics in primary teeth – A review

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    Sageena George

    2016-01-01

    Full Text Available Endodontic treatment in primary teeth can be challenging and time consuming, especially during canal preparation, which is considered one of the most important steps in root canal therapy. The conventional instrumentation technique for primary teeth remains the “gold-standard” over hand instrumentation, which makes procedures much more time consuming and adversely affects both clinicians and patients. Recently nickel–titanium (Ni–Ti rotary files have been developed for use in pediatric endodontics. Using rotary instruments for primary tooth pulpectomies is cost effective and results in fills that are consistently uniform and predictable. This article reviews the use of nickel–titanium rotary files as root canal instrumentation in primary teeth. The pulpectomy technique is described here according to different authors and the advantages and disadvantages of using rotary files are discussed.

  10. Múltiples dientes supernumerarios distomolares Multiple distomolars supernumerary teeth

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    F.J. Rodríguez Romero

    2009-12-01

    Full Text Available En una dentición normal, los dientes supernumerarios son aquellos descritos como adicionales a la serie. La etiología no esta clara. Se han descritos tanto en dentición primaria como en permanente, aunque son mas frecuentes en la dentición permanente. El objetivo de este informe es presentar un caso de una paciente con múltiples dientes supernumerarios distomolares. Cuartos molares bilaterales simétricos son sumamente raros.Supernumerary teeth are described as the teeth formed in excess of the number found in a normal dentition. The aetiology is not clear. Have been reported in both the primary and permanent dentition, although they are more prevalent in the permanent dentition. The purpose of this case report is to present a case of female patient with multiple distomolars supernumerary teeth. Bilateral symmetrical impacted fourth molars exceedingly uncommon.

  11. Biological restorations: Option of reincarnation for severely mutilated teeth

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    Kulvinder Kaur Wadhwani

    2013-01-01

    Full Text Available Objective: Esthetic and functional rehabilitation of severely mutilated fractured central incisors teeth using homogenous biological fragment bonding. Materials and Methods: Freshly extracted maxillary central incisors were treated endodontically and post spaces were prepared. Intra-radicular biological post core were fabricated from the sectioned roots of extracted canines. Cementation of biological post core in prepared space was done after clinical and radiological confirmation. Subsequent esthetic rehabilitation was done using adaptation of biological crown which was prepared from morphologically similar extracted maxillary central incisor. Results: The association between biological crowns and post core offers excellent esthetic, functional, and psychosocial results, which justifies the use of this technique to achieve the morphofunctional recovery of extensively damaged teeth. Conclusion: The biological restorations are an alternative technique for reconstruction of extensively damaged teeth that provides highly functional and esthetic outcomes.

  12. Subvertical grooves of interproximal facets in Neandertal posterior teeth.

    Science.gov (United States)

    Villa, G; Giacobini, G

    1995-01-01

    Subvertical grooves, located on the interproximal facets of most Neandertal posterior teeth, are less frequently noted on the teeth of other hominids, including modern humans. These grooves, 0.1-0.5 mm in width, are strictly localized within the facet area. Scanning electron microscopic (SEM) examination of grooves present on Neandertal teeth from Caverna delle Fate (Liguria, Italy) and Genay (Côte d'Or, France) demonstrated that they were produced during the life of these individuals. Characteristics of the groove surface suggest an erosion-abrasion mechanism of formation. These grooves, which developed in parts of the dentition exposed to marked stress, originated in areas characterized by changes in the orientation of enamel prism bundles (i.e., Hunter-Schreger bands). Observations carried out on modern human molars showed a subvertical disposition of these bands near interproximal ridges facilitating subvertical microfractures. Possible correlations between enamel structure, masticatory stress, and interproximal groove formation in Neandertals are discussed.

  13. Piracetam-induced changes on the brainstem auditory response in anesthetized juvenile rhesus monkeys (Macaca mulatta). Report of two clinical cases.

    Science.gov (United States)

    Durand-Rivera, A; Gonzalez-Pina, R; Hernandez-Godinez, B; Ibanez-Contreras, A; Bueno-Nava, A; Alfaro-Rodriguez, A

    2012-10-01

    We describe two clinical cases and examine the effects of piracetam on the brainstem auditory response in infantile female rhesus monkeys (Macaca mulatta). We found that the interwave intervals show a greater reduction in a 3-year-old rhesus monkey compared to a 1-year-old rhesus monkey. In this report, we discuss the significance of these observations. © 2012 John Wiley & Sons A/S.

  14. The significance of biometric parameters in determining anterior teeth width

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    Strajnić Ljiljana

    2013-01-01

    Full Text Available Background/Aim. An important element of prosthetic treatment of edentulous patients is selecting the size of anterior artificial teeth that will restore the natural harmony of one’s dentolabial structure as well as the whole face. The main objective of this study was to determine the correlation between the inner canthal distance (ICD and interalar width (IAW on one side and the width of both central incisors (CIW, the width of central and lateral incisors (CLIW, the width of anterior teeth (ATW, the width between the canine cusps (CCW, which may be useful in clinical practice. Methods. A total of 89 subjects comprising 23 male and 66 female were studied. Their age ranged from 19 to 34 years with the mean of 25 years. Only the subjects with the preserved natural dentition were included in the sample. All facial and intraoral tooth measurements were made with a Boley Gauge (Buffalo Dental Manufacturing Co., Brooklyn NY, USA having a resolution of 0.1mm. Results. A moderate correlation was established between the interalar width and combined width of anterior teeth and canine cusp width (r = 0.439, r = 0.374. A low correlation was established between the inner canthal distance and the width of anterior teeth and canine cusp width (r = 0.335, r = 0.303. The differences between the two genders were highly significant for all the parameters (p < 0.01. The measured facial distances and width of anterior teeth were higher in men than in women. Conclusion. The results of this study suggest that the examined interalar width and inner canthal distance cannot be considered reliable guidelines in the selection of artificial upper anterior teeth. However, they may be used as a useful additional factor combined with other methods for objective tooth selection. The final decision should be made while working on dentures fitting models with the patient’s consent.

  15. Root canal morphology of South asian Indian mandibular premolar teeth.

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    Singh, Shishir; Pawar, Mansing

    2014-09-01

    The purpose of this study was to study the root canal morphology of South Asian Indian mandibular premolars using a tooth clearing technique. Two hundred mandibular premolar teeth were collected from different dental schools and clinics in India. After pulp tissue removal and root canal staining with Indian ink, the specimens were decalcified with 5% nitric acid, dehydrated in ethyl alcohol, and subsequently cleared in methyl salicylate. Of the 200 mandibular premolars, 100 were first premolars and 100 were second premolars. Of the first premolars, 94% had a single root, whereas 6% were 2 rooted. Seventy-six percent had a single canal, 22% had 2 canals, and 2% had 3 canals. Eighty-two percent had a single apical foramen, 16% had 2 foramens, and 2% teeth had 3 apical foramens. Eighty percent of teeth had type I, 6% had type II, 10% had type IV, 2% had type V, and 2% teeth had type IX root canal anatomy. Of the 100 second premolars, 92% had a single root, whereas 8% teeth were 2 rooted and fused. Fifty-eight percent of teeth had a single canal, and 42% had two canals. Eighty-eight percent had a single apical foramen, and 12% had 2 foramens. Sixty-six percent had type I, 30% had type II, and 4% had type V root canal anatomy. A high prevalence of 2 canals was noted in the first and second premolars. Also, 20% of first premolars and 34% of second premolars had a root canal anatomy other than type I. Copyright © 2014 American Association of Endodontists. Published by Elsevier Inc. All rights reserved.

  16. Middle Pleistocene hominin teeth from Longtan Cave, Hexian, China.

    Science.gov (United States)

    Xing, Song; Martinón-Torres, María; Bermúdez de Castro, José María; Zhang, Yingqi; Fan, Xiaoxiao; Zheng, Longting; Huang, Wanbo; Liu, Wu

    2014-01-01

    Excavations at the Longtan Cave, Hexian, Anhui Province of Eastern China, have yielded several hominin fossils including crania, mandibular fragments, and teeth currently dated to 412 ± 25 ka. While previous studies have focused on the cranial remains, there are no detailed analyses of the dental evidence. In this study, we provide metric and morphological descriptions and comparisons of ten teeth recovered from Hexian, including microcomputed tomography analyses. Our results indicate that the Hexian teeth are metrically and morphologically primitive and overlap with H. ergaster and East Asian Early and mid-Middle Pleistocene hominins in their large dimensions and occlusal complexities. However, the Hexian teeth differ from H. ergaster in features such as conspicuous vertical grooves on the labial/buccal surfaces of the central incisor and the upper premolar, the crown outline shapes of upper and lower molars and the numbers, shapes, and divergences of the roots. Despite their close geological ages, the Hexian teeth are also more primitive than Zhoukoudian specimens, and resemble Sangiran Early Pleistocene teeth. In addition, no typical Neanderthal features have been identified in the Hexian sample. Our study highlights the metrical and morphological primitive status of the Hexian sample in comparison to contemporaneous or even earlier populations of Asia. Based on this finding, we suggest that the primitive-derived gradients of the Asian hominins cannot be satisfactorily fitted along a chronological sequence, suggesting complex evolutionary scenarios with the coexistence and/or survival of different lineages in Eurasia. Hexian could represent the persistence in time of a H. erectus group that would have retained primitive features that were lost in other Asian populations such as Zhoukoudian or Panxian Dadong. Our study expands the metrical and morphological variations known for the East Asian hominins before the mid-Middle Pleistocene and warns about the

  17. Case report of the radiation damage to the developing teeth

    Energy Technology Data Exchange (ETDEWEB)

    Tsutsumi, Nobuo; Rakugi, Masami; Kusamura, Yayoi; Ochiai, Nobuyuki; Saito, Takahiro (Osaka Univ. (Japan). School of Dentistry)

    1983-12-01

    In the treatment of malignant diseases about the head and neck, radium, x-rays and other radioactive materials are used as therapeutic agents. When irradiation is heavy, deleterious effects may be seen later in jaws, the teeh, or in both teeth and jaws. Young patients with undeveloped and developing teeth, despite lower dosages, are more subject to radiation damage to the teeth. After heavy exposure, grossly stunted teeth may appear. The crown is sometimes smaller than normal and deformed, and the root may be grossly underdeveloped. Sometimes the crown is formed normally but the roots are absent. This case is presented in which the mandibular jaw was irradiated at 3 years old and it was possible to examine some of the abnormal teeth in detail by using clinical, radiographic, and histologic technicques. The patient was first seen on June 21, 1982, at the age of 6 years old and one month. His medical history revealed that when he was 3 years old a malignant fibrous histiocytoma of the left mandibula. Radiation therapy (Linac) began at 3 years old and three months and extended over a period of one month. The total dose was 4750 rads. The crown of other teeth were formed normally but when the patient was 7 years old, the upper left lateral incisor was appeared to have short clinical crown. Radiographs revealed that roots of lower incisors were short and roots of molars were absent. The extracted lower molar was cut undecalcified to produce planoparallel section. The section showed that the dysplastic dentin was formed and it was continuous with the alveolar bone at the base of the tooth.

  18. Associations between the number of natural teeth and renal dysfunction.

    Science.gov (United States)

    Choi, Hye Min; Han, Kyungdo; Park, Yong Gyu; Park, Jun-Beom

    2016-08-01

    The purpose of the present study was to investigate the association between the number of natural teeth and measures of kidney dysfunction, such as urinary albumin/creatinine ratio (ACR) and estimated glomerular filtration (eGFR) rate, using nationally representative data.The data used were from the Korea National Health and Nutrition Examination Survey with cross-sectional design, which was conducted between 2011 and 2012; the sample analyzed in this study consisted of a total of 10,388 respondents, each of whom was 19 years or older and had no missing outcome variables. The association between the number of natural teeth and kidney function was assessed by multiple logistic regression and model was adjusted for age, sex, waist conference, smoking, drinking, exercise, education, income, frequency of tooth brushing per day, diabetes, metabolic syndrome, urinary ACR, and eGFR.The mean age, body mass index, and waist circumference were significantly higher among those with lower kidney function (urinary ACR ≥30 mg/g and eGFR natural teeth. As urinary ACR increased, the number of natural teeth decreased accordingly. Conversely, the number of natural teeth increased with an increase in eGFR.This study showed that the number of natural teeth is inversely associated with the presence of kidney disease. Severity of tooth loss may be considered an independent risk indicator for kidney disease among Koreans. More epidemiological studies are warranted to investigate the role of tooth loss in kidney disease, to confirm this relationship and to test possible underlying mechanisms.

  19. Prevalence of supernumerary teeth in a nonsyndromic Syrian sample.

    Science.gov (United States)

    Burhan, Ahmad S; Nawaya, Fehmieh R; Arabi Katbi, Mohammad E; Al-Jawabra, Alaa S

    2015-12-01

    Supernumerary teeth (ST), also known as hyperdontia, is a condition in which more than the normal number of teeth are present in the series. The prevalence of ST varies between and within different populations. These teeth may cause various complications. The aim of the current study was to investigate the prevalence and characteristics of ST in Damascus inhabitants, Syria. A cross-sectional study was carried out using retrospectively collected digital panoramic radiographs of 2753 patients (1047 males and 1706 females) ranging in age from 12.2 to 20.5 years between January 2012 and December 2014. These radiographs were obtained from private dental offices spread across Damascus, Syria. For each patient with ST, the demographic variables, number, location, type, position, morphology of ST, and complications were recorded. ST were detected in 39 patients (1.4%), of whom 25 (64.1%) were males and 14 (35.9%) were females, with a male to female ratio of 1.8 : 1 (PMesiodens was the most prevalent ST (39.1%), followed by supernumerary premolars (28.3%), supernumerary laterals (26.1%), distomolars (4.3%), and paramolars (2.2%). This series includes cases with one and two ST. Of the 46 ST detected, 56.5% had a conical morphology, 89.1% were in a vertical position, and 19.6% were erupted. ST caused displacement of the adjacent teeth in 17 cases (37.0%) and the impaction of the permanent teeth in five cases (10.9%). The prevalence of ST in Damascus inhabitants was found to be 1.4%; the most frequent type was mesiodens. A conical morphology was found to be the most common form of ST. Displacement of permanent teeth is the most frequent complication. Further studies should be carried out on more representative samples of both the public and the private sector patients.

  20. Demineralization–remineralization dynamics in teeth and bone

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    Abou Neel EA

    2016-09-01

    Full Text Available Ensanya Ali Abou Neel,1–3 Anas Aljabo,3 Adam Strange,3 Salwa Ibrahim,3 Melanie Coathup,4 Anne M Young,3 Laurent Bozec,3 Vivek Mudera4 1Division of Biomaterials, Operative Dentistry Department, Faculty of Dentistry, King Abdulaziz University, Jeddah, Saudi Arabia; 2Biomaterials Department, Faculty of Dentistry, Tanta University, Tanta, Egypt; 3Department of Biomaterials and Tissue Engineering, UCL Eastman Dental Institute, London, UK; 4UCL Institute of Orthopaedics and Musculoskeletal Sciences, Royal National Orthopaedic Hospital, Stanmore, London, UK Abstract: Biomineralization is a dynamic, complex, lifelong process by which living organisms control precipitations of inorganic nanocrystals within organic matrices to form unique hybrid biological tissues, for example, enamel, dentin, cementum, and bone. Understanding the process of mineral deposition is important for the development of treatments for mineralization-related diseases and also for the innovation and development of scaffolds. This review provides a thorough overview of the up-to-date information on the theories describing the possible mechanisms and the factors implicated as agonists and antagonists of mineralization. Then, the role of calcium and phosphate ions in the maintenance of teeth and bone health is described. Throughout the life, teeth and bone are at risk of demineralization, with particular emphasis on teeth, due to their anatomical arrangement and location. Teeth are exposed to food, drink, and the microbiota of the mouth; therefore, they have developed a high resistance to localized demineralization that is unmatched by bone. The mechanisms by which demineralization–remineralization process occurs in both teeth and bone and the new therapies/technologies that reverse demineralization or boost remineralization are also scrupulously discussed. Technologies discussed include composites with nano- and micron-sized inorganic minerals that can mimic mechanical properties

  1. Middle Pleistocene hominin teeth from Longtan Cave, Hexian, China.

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    Song Xing

    Full Text Available Excavations at the Longtan Cave, Hexian, Anhui Province of Eastern China, have yielded several hominin fossils including crania, mandibular fragments, and teeth currently dated to 412 ± 25 ka. While previous studies have focused on the cranial remains, there are no detailed analyses of the dental evidence. In this study, we provide metric and morphological descriptions and comparisons of ten teeth recovered from Hexian, including microcomputed tomography analyses. Our results indicate that the Hexian teeth are metrically and morphologically primitive and overlap with H. ergaster and East Asian Early and mid-Middle Pleistocene hominins in their large dimensions and occlusal complexities. However, the Hexian teeth differ from H. ergaster in features such as conspicuous vertical grooves on the labial/buccal surfaces of the central incisor and the upper premolar, the crown outline shapes of upper and lower molars and the numbers, shapes, and divergences of the roots. Despite their close geological ages, the Hexian teeth are also more primitive than Zhoukoudian specimens, and resemble Sangiran Early Pleistocene teeth. In addition, no typical Neanderthal features have been identified in the Hexian sample. Our study highlights the metrical and morphological primitive status of the Hexian sample in comparison to contemporaneous or even earlier populations of Asia. Based on this finding, we suggest that the primitive-derived gradients of the Asian hominins cannot be satisfactorily fitted along a chronological sequence, suggesting complex evolutionary scenarios with the coexistence and/or survival of different lineages in Eurasia. Hexian could represent the persistence in time of a H. erectus group that would have retained primitive features that were lost in other Asian populations such as Zhoukoudian or Panxian Dadong. Our study expands the metrical and morphological variations known for the East Asian hominins before the mid-Middle Pleistocene and

  2. Múltiples dientes supernumerarios distomolares Multiple distomolars supernumerary teeth

    OpenAIRE

    F.J. Rodríguez Romero; S. Cerviño Ferradanes

    2009-01-01

    En una dentición normal, los dientes supernumerarios son aquellos descritos como adicionales a la serie. La etiología no esta clara. Se han descritos tanto en dentición primaria como en permanente, aunque son mas frecuentes en la dentición permanente. El objetivo de este informe es presentar un caso de una paciente con múltiples dientes supernumerarios distomolares. Cuartos molares bilaterales simétricos son sumamente raros.Supernumerary teeth are described as the teeth formed in excess of th...

  3. On The Evolution of Human Jaws and Teeth: A Review

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    Serhat Yalcin

    2011-06-01

    Full Text Available The jaws and teeth of Homo sapiens have evolved, from the last common ancestor of chimpanzee and men to their current form. Many factors such as the foods eaten and the processing of foods by fire and tools have effected this evolution course. The evolution of the masticatory complex is related to other anatomical features such as brain size and bipedal posture, and leads to important proceedings like the formation of speech and language. In this review, the evolution of human jaws and teeth and its impact on the general course of human evolution is discussed.

  4. Microhardness of teeth enamel on whitening combined with remineralization treatment

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    Gabriela Strnad

    2011-12-01

    Full Text Available The aim of this study was to evaluate the effect of different bleaching agents used for teeth whitening on the microhardness of the enamel. 35% HP and 17% CP were applied on several samples of human incisors. Different treatment strategies were followed and the results show that all of bleaching agents caused a reduction in Vickers microhardness of specimens. Remineralization treatment was applied on samples, after this process the microhardness of the teeth being restored close to initial values measured prior to whitening.

  5. Iatrogenic mid-root perforation of fused teeth

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    Vijay Kumar

    2012-01-01

    Full Text Available Fusion is defined as a union between the dentin and/or enamel of two or more distinct dental sprouts that occurs at any stage of the dental organ. Its prevalence ranges from 0.5%-2.5% in the primary dentition alone and 0.1%-1% of the primary as well as the permanent dentition. These fused teeth can cause various problems such as caries, periodontal disease, abnormal eruption, impaction or an ectopic eruption of an adjacent tooth and reported in the literature. However this paper documented an unusual case of iatrogenic root perforation of fused permanent lower anterior teeth during inter maxillary fixation.

  6. Macroscopic description of teeth of Azara's agouti (Dasyprocta azarae

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    Fabrício S. Oliveira

    2012-01-01

    Full Text Available The teeth of Azara's agouti (Dasyprocta azarae were described macroscopically in order to provide biological data on one of the largest wild rodents of the Americas. Radiography was taken on six heads and the teeth were described. Enamel surrounds the coronal dentin, projects to the roots and is present as parallel inner laminae in buccolingual direction. The dentin is located among the enamel laminae and surrounds the pulp horns. The cementum is located internally to the enamel laminae. On the lingual surface, the cementum and dentin are the outer elements.

  7. How Reliable Is Sex Differentiation From Teeth Measurements

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    Harish R.K

    2013-01-01

    Full Text Available Gender determination of human remains recovered in forensic contexts constitutes an important step in medico-legal examination. The ability of the inert, mineralized structures of teeth to resist post-mortem degradation and to survive deliberate, accidental or natural change has led forensic experts to focus on the teeth as a possible source for valuable forensic data in fragmentary and poorly preserved human remains. Numerous studies show that tooth size standards based on odontometric investigations are population specific and can be used in age and sex determination. This paper reviews the methods of determining sex by odontometrics, tooth proportions and sexual dimorphism.

  8. Prosthodontic considerations concerning the abutment teeth of the irradiated patient

    Energy Technology Data Exchange (ETDEWEB)

    Nitta, Eiji; Taniguchi, Hisashi; Ohyama, Takashi; Takeda, Masamune (Tokyo Medical and Dental Univ. (Japan). School of Dentistry)

    1984-06-01

    There still remain several prosthodontic problems for the patient who has received radiation therapy for oral cancer because of radiation injury. We have experienced these in applying a tooth-borne denture to such a patient. Subsequently, it has been recognized that the longevity of the abutment teeth in such a denture is extremely short, compared with the ordinary case. Therefore, when designing the prosthesis for the irradiated patients, it is imperative that we pay special attention to the decreased vitality of the supporting bones of the abutment teeth, as well as to the weakened mucous membrane and rampant caries.

  9. Tetracycline-induced discoloration of deciduous teeth: case series.

    Science.gov (United States)

    Vennila, Vijayasree; Madhu, Vasapalli; Rajesh, R; Ealla, Kranti Kiran Reddy; Velidandla, Surekha Reddy; Santoshi, S

    2014-06-01

    Tetracycline was the choice of antibiotic in some of the life-threatening bacterial infections. Due to its adverse effects and ability to cross-placental barrier, its use is contraindicated in pregnancy and in children. This is a case series of four patients with tetracycline-induced discoloration in primary teeth. How to cite the article: Vennila V, Madhu V, Rajesh R, Ealla KKR, Velidandla SR, Santoshi S. Tetracycline induced discoloration of deciduous teeth: Case series. J Int Oral Health 2014;6(3):115-9.

  10. Scanning electron microscopy and electron probe X-ray microanalysis (SEM-EPMA) of pink teeth

    Energy Technology Data Exchange (ETDEWEB)

    Ikeda, N.; Watanabe, G.; Harada, A.; Suzuki, T.

    1988-11-01

    Samples of postmortem pink teeth were investigated by scanning electron microscopy and electron probe X-ray microanalysis. Fracture surfaces of the dentin in pink teeth were noticeably rough and revealed many more smaller dentinal tubules than those of the control white teeth. Electron probe X-ray microanalysis showed that the pink teeth contained iron which seemed to be derived from blood hemoglobin. The present study confirms that under the same circumstance red coloration of teeth may occur more easily in the teeth in which the dentin is less compact and contains more dentinal tubules.

  11. Retrospective study of teeth with a poor prognosis following non-surgical periodontal treatment.

    Science.gov (United States)

    Ekuni, Daisuke; Yamamoto, Tatsuo; Takeuchi, Noriko

    2009-04-01

    The aim of this retrospective study was to assess teeth with a poor prognosis and the proximal periodontium of adjacent teeth, and to identify the risk factors associated with the loss of teeth with a poor prognosis following non-surgical periodontal treatment. Teeth with a poor prognosis (n=113), teeth adjacent to those of poor prognosis (n=105) and non-adjacent teeth (n=51) were evaluated in 25 non-smoking patients who had received supportive periodontal treatment for 5-16 years following non-surgical periodontal treatment at a university hospital. Probing pocket depth (PPD), percentage of alveolar bone loss, presence of tooth mobility and bleeding on probing in all teeth improved significantly after treatment. Logistic regression analysis showed that loss of teeth with a poor prognosis depended on the initial deepest PPD, tooth mobility and multi-rooted tooth. Teeth with a poor prognosis did not affect the proximal periodontium of the adjacent teeth, and progression of periodontal disease in these teeth and adjacent teeth can be prevented by non-surgical periodontal treatment in non-smokers. The risk factors for loss of teeth with a poor prognosis were the initial deepest PPD, tooth mobility and multi-rooted tooth.

  12. Histologic Outcomes of Uninfected Human Immature Teeth Treated with Regenerative Endodontics: 2 Case Reports.

    Science.gov (United States)

    Nosrat, Ali; Kolahdouzan, Alireza; Hosseini, Farzaneh; Mehrizi, Ehsan A; Verma, Prashant; Torabinejad, Mahmoud

    2015-10-01

    A growing body of evidence exists showing the possibility of growing vital tissues in the root canal spaces of teeth with necrotic pulps and open apices. However, there is very limited histologic information regarding characteristics of tissues formed in the root canal space of human teeth after regenerative endodontics. The aim of this study was to examine clinically and histologically the outcomes of human immature teeth treated with regenerative endodontics. Two healthy birooted human maxillary first premolar teeth scheduled for extraction were included. Preoperative radiographs confirmed that these teeth had immature apices. Vitality tests showed the presence of vital pulps in these teeth. After receiving consent forms, the teeth were isolated with a rubber dam, and the pulps were completely removed. After the formation of blood clots in the canals, the teeth were covered with mineral trioxide aggregate. Four months later, the teeth were clinically and radiographically evaluated, extracted, and examined histologically. Both patients remained asymptomatic after treatment. Radiographic examination of the teeth showed signs of root development after treatment. Histologic examination of tissues growing into the root canal space of these teeth shows the presence of connective tissue, bone and cementum formation, and thickening of roots. Based on our findings, it appears that when canals of teeth with open apices are treated with regenerative endodontics, tissues of the periodontium grow into the root canals of these teeth. Copyright © 2015 American Association of Endodontists. Published by Elsevier Inc. All rights reserved.

  13. Fracture strength of teeth restored with ceramic inlays and overlays.

    Science.gov (United States)

    Morimoto, Susana; Vieira, Glauco Fioranelli; Agra, Carlos Martins; Sesma, Newton; Gil, Carlos

    2009-01-01

    This study evaluated the fracture strength of teeth restored with bonded ceramic inlays and overlays compared to sound teeth. Thirty sound human maxillary premolars were assigned to 3 groups: 1- sound/unprepared (control); 2- inlays and 3- overlays. The inlay cavity design was Class II MOD preparation with an occlusal width of 1/2 of the intercuspal distance. The overlay cavity design was similar to that of the inlay group, except for buccal and palatal cusp coverage The inlay and overlay groups were restored with feldspathic porcelain bonded with adhesive cement. The specimens were subjected to a compressive load until fracture. Data were analyzed statistically by the Kruskal-Wallis test at 5% significance level. The fracture strength means (KN) were: Sound/unprepared group = 1.17, Inlay group= 1.17, and Overlay group = 1.14. There were no statistically significant differences (p>0.05) among the groups. For inlays and overlays, the predominant fracture mode involved fragments of one cusp (70% of simple fractures). The fracture strength of teeth restored with inlay and overlay ceramics with cusp coverage was similar to that of intact teeth.

  14. Clinical survey on type of restoration in deciduous teeth.

    Science.gov (United States)

    Fukuyama, Tatsuro; Oda, Shinya; Yamashita, Haruto; Sekiguchi, Hiroshi; Yakushiji, Masashi

    2008-02-01

    This study was conducted in 533 children with 1,634 treated teeth who visited the Pediatric Dentistry Department at the Chiba Hospital of Tokyo Dental College between January and December, 2003. Restorations on deciduous tooth were categorized by age of patient and tooth type. The following observations were made: Children aged 4 (17.9%) visited the clinic most frequently and this group had the highest number of deciduous restorations (21.3%). Among the 1,634 deciduous teeth restored, metal inlays were provided in 29.4% of total teeth restored, composite resin restorations in 27.2%, stainless-steel crowns in 25.7%, composite resin full crowns in 7.7%, glass-ionomer cement restorations in 6.6%, and amalgam restorations in 3.4%. By age, composite resin was most frequently used in children aged 1 to 3. In children aged 5 to 9, metal inlay was most frequently used. Those aged 4 received mostly stainless-steel crowns. Composite resin restorations were used mostly in anterior deciduous teeth, and metal inlays mostly in deciduous molars. Previous research indicated an increasing trend towards composite resin restorations and composite resin full crowns. The present study also confirmed such a trend. While the use of metal inlays and stainless-steel crowns tended to increase until 1987, the present study indicated a trend to decrease.

  15. Orthodontics Align Crooked Teeth and Boost Self-Esteem

    Science.gov (United States)

    ... how your teeth and mouth change in every stage of life. More RSS Feeds Get dental news ... general dentist with a good perspective of the development of the child's dentition and any need for orthodontics," explains Dr. ... risk of gum decay, tooth decay and tooth loss Improved self-esteem for ...

  16. Implants and/or teeth: consensus statements and recommendations

    DEFF Research Database (Denmark)

    Gotfredsen, K; Carlsson, G E; Jokstad, A

    2008-01-01

    In August 23-25, 2007, the Scandinavian Society for Prosthetic Dentistry in collaboration with the Danish Society of Oral Implantology arranged a consensus conference on the topic 'Implants and/or teeth'. It was preceded by a workshop in which eight focused questions were raised and answered...

  17. A remarkable feature in the dentine of teeth of Odontocetes

    NARCIS (Netherlands)

    Utrecht, van W.L.

    1969-01-01

    The neonatal line in teeth of Phocoena phocoena is studied. The length of the neonatal line measured from the upper end of the cementum to the point where the line ends against that layer, may offer an indication for sex determination in this species.

  18. Fracture resistance of premolar teeth restored with different filling techniques.

    Science.gov (United States)

    França, Fabiana Mantovani Gomes; Worschech, Claudia Cia; Paulillo, Luis Alexandre Maffei Sartini; Martins, Luis Roberto Marcondes; Lovadino, José Roberto

    2005-08-15

    The aim of this study is to verify the fracture resistance of premolars with large mesiocclusodistal (MOD) preparations with composite resin using different incremental techniques when subjected to an occlusal load. Forty maxillary premolar teeth were randomly divided into four groups (n=10). Class II MOD cavities were prepared in all specimens with parallel walls and no approximal boxes. The resulting isthmus width was 1/3 the distance between the cusp tips and (3/4) the height of the crown. Teeth in group I, the control group, were not restored. Specimens in group II were restored in three incremental vertical layers. Group III specimens were restored in three horizontal layers, and finally, specimens in group IV were restored in oblique layers. With exception of the placement technique, specimens in groups II, III and IV were restored using the Single Bond adhesive system and P60 composite resin following manufacturer's recommendations. A 4 mm diameter steel sphere contacted the buccal and lingual cusps of the tested teeth at a crosshead speed of 0.5 mm/min until fracture occurred. The values obtained in this study were subjected to Analysis of Variance (ANOVA) and a Tukey-Kramer test. Only group I (non-restored) obtained a minor means of fracture resistance. No significant differences among groups II, III, and IV were found. This study shows on large MOD cavities the incremental filling techniques do not influence the fracture resistance of premolar teeth restored with composite resin.

  19. [Orthodontics in general practice 4. Impaction of maxillary front teeth

    NARCIS (Netherlands)

    Swart, R.J.; Kiekens, R.M.A.; Borstlap, W.A.; Kuijpers-Jagtman, A.M.

    2008-01-01

    Eruption failures in the maxillary frontal region occur during the mixed dentition period. Dislocation and impaction of central incisors are diagnosed during or at the end of the early mixed dentition stage. These failures can be caused by crowding, premature loss of deciduous teeth, trauma or super

  20. A survey of natal and neonatal teeth in newborn infants

    Directory of Open Access Journals (Sweden)

    Chun-Hsiang Wang

    2017-03-01

    Conclusion: Most of the natal or neonatal teeth were in the mandibular primary incisor position and not all of them were supernumerary. No gender differences were found in tooth morphology, positive family history, and treatment methods. The tooth morphology was not significantly related to a positive family history, premature delivery, or the mother's physical condition before delivery.

  1. Mercury Amalgam Diffusion in Human Teeth Probed Using Femtosecond LIBS.

    Science.gov (United States)

    Bello, Liciane Toledo; da Ana, Patricia Aparecida; Santos, Dário; Krug, Francisco José; Zezell, Denise Maria; Vieira, Nilson Dias; Samad, Ricardo Elgul

    2017-01-01

    In this work the diffusion of mercury and other elements from amalgam tooth restorations through the surrounding dental tissue (dentin) was evaluated using femtosecond laser-induced breakdown spectroscopy (fs-LIBS). To achieve this, seven deciduous and eight permanent extracted human molar teeth with occlusal amalgam restorations were half-sectioned and analyzed using pulses from a femtosecond laser. The measurements were performed from the amalgam restoration along the amalgam/dentin interface to the apical direction. It was possible to observe the presence of metallic elements (silver, mercury, copper and tin) emission lines, as well as dental constituent ones, providing fingerprints of each material and comparable data for checking the consistence of the results. It was also shown that the elements penetration depth values in each tooth are usually similar and consistent, for both deciduous and permanent teeth, indicating that all the metals diffuse into the dentin by the same mechanism. We propose that this diffusion mechanism is mainly through liquid dragging inside the dentin tubules. The mercury diffused further in permanent teeth than in deciduous teeth, probably due to the longer diffusion times due to the age of the restorations. It was possible to conclude that the proposed femtosecond-LIBS system can detect the presence of metals in the dental tissue, among the tooth constituent elements, and map the distribution of endogenous and exogenous chemical elements, with a spatial resolution that can be brought under 100 µm.

  2. Esthetic removable partial denture design in replacing maxillary anterior teeth.

    Science.gov (United States)

    Oh, Won-Suk; Basho, Shveta

    2010-01-01

    Prosthodontic rehabilitation of missing maxillary anterior teeth requires special consideration to restore function and esthetics. This case report describes the prosthodontic management of a patient who lost three maxillary incisors due to a motor vehicle accident. A rotational path removable partial denture was constructed, for which a proximal undercut was created by means of a composite buildup to provide the retention for the prosthesis.

  3. Mineral content in teeth with Deciduous Molar Hypomineralisation (DMH)

    NARCIS (Netherlands)

    Elfrink, M.E.C.; ten Cate, J.M.; van Ruijven, L.J.; Veerkamp, J.S.J.

    2013-01-01

    Objectives We report the mineral (hydroxyapatite) density of sound and opaque areas in DMH molars with sound parts of (carious) deciduous teeth serving as controls. Methods Twenty-nine extracted second primary molars obtained from 15 children were studied. Thirteen of these molars were DMH molars

  4. Outcome of Endodontically Treated Teeth Diagnosed With Cracked Tooth

    Science.gov (United States)

    2015-06-01

    However, variable symptoms complicate the diagnosis (9). In a study of 32 patients presenting with diffuse longstanding orofacial pain eventually...883-92. 22)Byrnjulsen A, Fristad I, Grevstad T, Hals-Kvinnsland I. Incompletely fractured teeth associated with diffuse longstanding orofacial pain

  5. Supernumerary Teeth in Indian Children: A Survey of 300 Cases

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    Amita Sharma

    2012-01-01

    Full Text Available The aim of this investigation was to study children with supernumerary teeth who visited the Department of Pedodontics and Preventive Dentistry, Government Dental College and Hospital, Rohtak, Haryana, India. Only children with supernumerary teeth were included in the study while patients having supernumerary teeth with associated syndromes were excluded. Supernumeraries were detected by clinical and radiographic examination. The results indicated that males were affected more than females with a sex ratio of 2.9 : 1. Single supernumerary tooth was seen in 79% of the patients, 20% had double, and 1% had three or more supernumeraries. Premaxillary supernumeraries accounted for 93.8% of the cases. Conical shaped supernumerary teeth were the most common type (59.7%. Majority of supernumeraries remained unerupted (65%. Fusion of supernumerary tooth with a regular tooth was observed in 4% of the patients. Talon cusp, an associated dental anomaly, was seen in 5% of the cases. Simultaneous hypodontia occurred in 2.3% of patients with supernumeraries.

  6. Oral Hygiene Practices and Teeth Cleaning Techniques Among Medical Students.

    Science.gov (United States)

    Naseem, Sajida; Fatima, Syeda H; Ghazanfar, Haider; Haq, Sana; Khan, Najeeb A; Mehmood, Moeez; Ghazanfar, Ali

    2017-07-18

    Objectives Oral health is essential for general health and quality of life. It is a state of being free from mouth and facial pain, oral and throat cancer, oral infections and sores, periodontal disease, tooth decay, tooth loss, and other diseases and disorders that limit an individual's capacity to bite, chew, smile, and speak; it affects psychosocial well-being too. The objective of our study was to assess teeth cleaning techniques and oral hygiene practices among medical students. Methods The data of the study were collected in two stages. The first stage involved the administration of a self-constructed questionnaire among medical students. In the second step, the students were asked to demonstrate their teeth cleaning techniques on a model. A standard teeth cleaning checklist was used to evaluate the students. The students were then given the checklist and a video on teeth cleaning techniques was shown to them. The data obtained was analyzed on IBM's statistical package for the social sciences (SPSS) version 21.  Results Out of a total of 444 students, 256 (57.7 percent) were males while 188 (42.3 percent) were females. About 254 (57.2 percent) participants were preclinical medical students while 190 (42.8 percent) were clinical year medical students. A majority of medical students used medium consistency toothbrushes (177; 39.9 percent) and soft consistency toothbrushes (137; 30.9 percent). Most medical students (248; 55.9 percent) brushed two times a day while 163 (36.7 percent) brushed only one time. About 212 (47.7 percent) of the medical students used mouthwash along with a toothbrush while only 36 (8.1 percent) used floss along with a toothbrush. About 157 participants (35.4 percent) changed their toothbrush once in two months while 132 (26.7 percent) changed their toothbrush once in three months. The mean duration that participants brushed their teeth was 134.99 ± 69.01 seconds. Conclusion Medical students were found to have a faulty teeth

  7. Scorching effects of heat on extracted teeth - A forensic view

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    Ajay P Prakash

    2014-01-01

    Full Text Available Context: Fire investigation is the multidisciplinary basis of the exploration, which involves investigations concerning the origin of fire, its cause as well as the identification of victims. At times, victim identification in fire disasters becomes nearly impossible owing to complete destruction of soft tissues. In such circumstances, teeth may prove to be of value since they are extremely hard. A precise understanding of physical and histological changes in teeth subjected to high temperature can provide valuable clues in fire and crime investigations, when dental evidence remains. Aim: The main aim and objective of the study was to investigate structural damage in freshly extracted teeth to heating, at different temperatures for a certain length of time in the laboratory. Settings and Design: Fifty-four freshly extracted teeth of different age groups had been subjected to different temperatures for a period of 15 minutes in the laboratory furnace. Physical and microscopic findings were correlated to the temperature. Materials and Methods: Freshly extracted 54 permanent teeth of different age groups were collected and were subjected to temperatures of 100°C, 300°C, and 600°C. Teeth were then examined for any physical changes such as change in color, texture, or morphology that occurred. Then the teeth were subjected for decalcification following which the tissues were kept for routine processing and were embedded in paraffin wax. Sections of 4 μm thickness were made and stained in hematoxylin and eosin (H and E to correlate the microscopic findings to the temperature. Statistical Analysis: Physical and microscopic findings were correlated to the temperature. Results: Microscopic examination revealed definite histological patterns, which were explicitly seen at a particular temperature. The samples showed cracks and charring of the tooth structure with microscopic findings such as widening of dentinal tubules and altered histological

  8. Primate dental ecology: How teeth respond to the environment.

    Science.gov (United States)

    Cuozzo, Frank P; Ungar, Peter S; Sauther, Michelle L

    2012-06-01

    Teeth are central for the study of ecology, as teeth are at the direct interface between an organism and its environment. Recent years have witnessed a rapid growth in the use of teeth to understand a broad range of topics in living and fossil primate biology. This in part reflects new techniques for assessing ways in which teeth respond to, and interact with, an organism's environment. Long-term studies of wild primate populations that integrate dental analyses have also provided a new context for understanding primate interactions with their environments. These new techniques and long-term field studies have allowed the development of a new perspective-dental ecology. We define dental ecology as the broad study of how teeth respond to, or interact with, the environment. This includes identifying patterns of dental pathology and tooth use-wear, as they reflect feeding ecology, behavior, and habitat variation, including areas impacted by anthropogenic disturbance, and how dental development can reflect environmental change and/or stress. The dental ecology approach, built on collaboration between dental experts and ecologists, holds the potential to provide an important theoretical and practical framework for inferring ecology and behavior of fossil forms, for assessing environmental change in living populations, and for understanding ways in which habitat impacts primate growth and development. This symposium issue brings together experts on dental morphology, growth and development, tooth wear and health, primate ecology, and paleontology, to explore the broad application of dental ecology to questions of how living and fossil primates interact with their environments. Copyright © 2012 Wiley Periodicals, Inc.

  9. Pulp microbiology of complete teeth with idiopathic apical lesions.

    Directory of Open Access Journals (Sweden)

    Patricia Rodríguez

    2009-11-01

    Full Text Available Introduction: Periapical changes named as lesions, in teeth with full crown integrity and without history of trauma, do not show a clear aetiology. Objective: To determine the presence of microorganisms in pulp dental tissue will clarify the cause of its death and therefore the damage to periodontal tissues. Materials and methods: From people between 10 and 39 years old, 23 teeth were selected. The samples were taken with paper points and 0.8 sterile files, and were transported in VMGA III medium, to be processed in the following 24 hours after they were taken and sowed in Brucella-agar. Results: The most affected teeth were upper central incisors, 43.8%. From the 23 studied teeth, microbiological grow was seen on 20 teeth. The following microorganisms species were identified: Fusobacterium spp., 25%, Eubacterium spp., 15%; Peptostreptococcus spp., 10%; Campylobacter spp., 10%; gram negative enteric bacteria, 10%; Porphyromonas gingivalis, 10%; Prevotella intermedia, 5%; Eikenellia corrodens, 5%; Dialister pneumosintes, 5%; and yeasts, 5%. There was no growing evidence of Actinomyces actinomycetemcomitans, Tanerella forsythensis and Streptococcus β  hemolytic. Discussion and conclusions: Sound pulp dental tissue is sterile; an injury over it will cause its inflammation, degeneration, death and bacterial contamination. Results in the present study clearly show the presence of microorganisms in closed apical dental lesions of endodontic origin. In same manner, it was seen that a great part of microorganisms species found can be regarded as periodontal pathogens. This could suggest a management with an endodontic, a periodontic and a pharmacological combined treatment.

  10. Hen's teeth with enamel cap: from dream to impossibility

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    Girondot Marc

    2008-09-01

    Full Text Available Abstract Background The ability to form teeth was lost in an ancestor of all modern birds, approximately 100-80 million years ago. However, experiments in chicken have revealed that the oral epithelium can respond to inductive signals from mouse mesenchyme, leading to reactivation of the odontogenic pathway. Recently, tooth germs similar to crocodile rudimentary teeth were found in a chicken mutant. These "chicken teeth" did not develop further, but the question remains whether functional teeth with enamel cap would have been obtained if the experiments had been carried out over a longer time period or if the chicken mutants had survived. The next odontogenetic step would have been tooth differentiation, involving deposition of dental proteins. Results Using bioinformatics, we assessed the fate of the four dental proteins thought to be specific to enamel (amelogenin, AMEL; ameloblastin, AMBN; enamelin, ENAM and to dentin (dentin sialophosphoprotein, DSPP in the chicken genome. Conservation of gene synteny in amniotes allowed definition of target DNA regions in which we searched for sequence similarity. We found the full-length chicken AMEL and the only N-terminal region of DSPP, and both are invalidated genes. AMBN and ENAM disappeared after chromosomal rearrangements occurred in the candidate region in a bird ancestor. Conclusion These findings not only imply that functional teeth with enamel covering, as present in ancestral Aves, will never be obtained in birds, but they also indicate that these four protein genes were dental specific, at least in the last toothed ancestor of modern birds, a specificity which has been questioned in recent years.

  11. Fracture strength of composite fixed partial denture using bovine teeth as a substitute for human teeth with or without fiber-reinforcement.

    Science.gov (United States)

    Soares, Carlos José; Barbosa, Liliane Minglini; Santana, Fernanda Ribeiro; Soares, Priscilla Barbosa Ferreira; Mota, Adérito Soares da; Silva, Gisele Rodrigues da

    2010-01-01

    This study evaluate the use of bovine teeth as a substitute for human teeth on fracture strength tests of composite fixed partial dentures (Cpd), with and without fiberglass reinforcement (Fg). Eighty teeth were selected, being 40 bovine incisors, 20 human premolars and 20 molars. Bovine incisors were ground to get a platform, simulating an occlusal surface of human molar. Teeth in pairs were embedded in polystyrene resin, simulating the periodontal ligament and divided in 4 groups: B-Cpd-Fg: bovine teeth restored with Cpd with Fg; B-Cpd-NFg: bovine teeth restored with Cpd without Fg; H-Cpd-Fg: human teeth restored Cpd with Fg; and H-Cpd-NFg: human teeth restored with Cpd without Fg. The Cpd were adhesively fixed and submitted to an axial compression load at the pontic center with a crosshead speed of 0.5 mm/min until fracture. Failure modes were assessed and classified. Data were subjected to two-way ANOVA and Tukey's HSD test (α=0.05). The tooth type had no influence on fracture strength and fracture mode. The inclusion of fiberglass increased significantly the fracture strength. The failure modes were more reparable in groups with fiber-reinforcement. Bovine teeth can be used as a substitute for human teeth in these types of fracture strength tests.

  12. Parental beliefs about children's teething in Udaipur, India: a preliminary study

    Directory of Open Access Journals (Sweden)

    Gauri Kakatkar

    2012-04-01

    Full Text Available Throughout history, teething has been held responsible for a variety of childhood illnesses. The objective of this study was to assess parents' knowledge and beliefs about teething signs and symptoms and to investigate the practices used to alleviate teething troubles. A cross-sectional survey was conducted using a self-administered questionnaire distributed to 550 parents in Udaipur, India. The questionnaire contained three sections eliciting demographic characteristics and assessing parents' knowledge, beliefs, and practices regarding teething. Statistical analysis used descriptive statistics and the chi-squared test (p £ 0.05. Response to teething was incorrectly attributed to fever (70%, diarrhea (87.5%, and sleep disturbances (48.2%. Only 33.2% of parents allowed their children to bite on chilled objects to relieve symptoms associated with teething. A common lack of knowledge about teething among parents should encourage dental healthcare providers to educate them regarding the teething process and its management.

  13. Parental beliefs about children's teething in Udaipur, India: a preliminary study.

    Science.gov (United States)

    Kakatkar, Gauri; Nagarajappa, Ramesh; Bhat, Nagesh; Prasad, Vikas; Sharda, Archana; Asawa, Kailash

    2012-01-01

    Throughout history, teething has been held responsible for a variety of childhood illnesses. The objective of this study was to assess parents' knowledge and beliefs about teething signs and symptoms and to investigate the practices used to alleviate teething troubles. A cross-sectional survey was conducted using a self-administered questionnaire distributed to 550 parents in Udaipur, India. The questionnaire contained three sections eliciting demographic characteristics and assessing parents' knowledge, beliefs, and practices regarding teething. Statistical analysis used descriptive statistics and the chi-squared test (p £ 0.05). Response to teething was incorrectly attributed to fever (70%), diarrhea (87.5%), and sleep disturbances (48.2%). Only 33.2% of parents allowed their children to bite on chilled objects to relieve symptoms associated with teething. A common lack of knowledge about teething among parents should encourage dental healthcare providers to educate them regarding the teething process and its management.

  14. BILATERAL MOLARIFORM SUPERNUMERARY TEETH IN THE ANTERIOR MAXILLA: A REPORT OF TWO CASES

    Directory of Open Access Journals (Sweden)

    Mehmet Cem ÖZDEN

    2017-01-01

    Full Text Available Supernumerary teeth are additional teeth besides the normal series and can be found in any region of the dental arch. Supernumerary teeth can be classified according to their form and locations. Early diagnosis and treatment of patients with supernumerary teeth may prevent or minimize complications. The treatment options depend on the type and position of the supernumerary tooth and its effect on the adjacent structures. Two male patients were referred to our clinic due to swelling in their maxillae and interrupted eruption of teeth. Upon radiological examination of the patients, impacted supernumerary teeth were found. Surgical removal of these teeth were perfomed and they were found to be molariform. We aim to present the two rare cases of molariform supernumerary teeth in this article.

  15. Sequential supernumerary teeth development in a non-syndromic patient; report of a rare case.

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    Mohammad Jafarian

    2013-12-01

    Full Text Available Isolated impacted supernumerary teeth are quite rare, but they can be seen associated with several syndromes such as cleidocranial dysostosis or Gardner's syndrome. This article aims to discuss a case of sequential formation of supernumerary teeth with no other associated disease or syndrome. A 17-year-old Iranian male with 8 impacted supernumerary teeth was referred to the department of pediatric dental clinic at Shahid Beheshti Medical University in Tehran with a history of several impacted unerupted teeth. Repeated and periodical clinical and radiographic examinations revealed newly formed teeth buds in unusual dental ages. All extra teeth were associated with generalized enamel hypoplasia to some degree on their relative permanent adjacent teeth. The patient did not have any record of a systemic disease or any syndromic condition to relate his dental problem to. This rare condition involved repeated and continued formation of extra teeth out of the normal numbers and dental age evident in serial radiographs.

  16. Supragingival Microbial Profiles of Permanent and Deciduous Teeth in Children with Mixed Dentition

    National Research Council Canada - National Science Library

    Shi, Weihua; Qin, Man; Chen, Feng; Xia, Bin

    2016-01-01

    The present study was designed to investigate the microbial profiles of teeth in different locations in mixed-dentition-stage children, and to compare the microbiomes of permanent and deciduous teeth...

  17. IN VITRO WEAR RESISTANCE OF THREE TYPES OF POLYMETHYL METHACRYLATE DENTURE TEETH

    OpenAIRE

    Katia Rodrigues Reis; Gerson Bonfante; Luiz Fernando Pegoraro; Paulo Cesar Rodrigues Conti; Pedro Cesar Garcia de Oliveira; Osvaldo Bazzan Kaizer

    2008-01-01

    The wear resistance of denture teeth is important to the longevity of removable prostheses of edentulous patients. The ability of denture teeth to maintain a stable occlusal relationship over time may be influenced by this property. The purpose of this in vitro study was to evaluate the wear resistance of polymethyl methacrylate (PMMA) denture teeth based on their chemical composition when opposed by a ceramic antagonist. The maxillary canines (n=10) of 3 PMMA denture teeth (Trubyte Biotone, ...

  18. Mesiodens with an unusual morphology and multiple impacted supernumerary teeth in a non-syndromic patient.

    Science.gov (United States)

    Srivatsan, Pavithra; Aravindha Babu, N

    2007-01-01

    Supernumerary teeth are a relatively frequent disorder of odontogenesis characterized by an excess number of teeth. Mesiodens is the most common type of supernumerary tooth found in the premaxilla between the two central incisors. They can be supplemental (resembling natural teeth), conical, tuberculate or molariform. We present the case of a 19 year-old girl who presented with a mesiodens of an unusual morphology and multiple impacted supernumerary teeth not associated with any syndrome.

  19. Mesiodens with an unusual morphology and multiple impacted supernumerary teeth in a non-syndromic patient

    Directory of Open Access Journals (Sweden)

    Srivatsan Pavithra

    2007-01-01

    Full Text Available Supernumerary teeth are a relatively frequent disorder of odontogenesis characterized by an excess number of teeth. Mesiodens is the most common type of supernumerary tooth found in the premaxilla between the two central incisors. They can be supplemental (resembling natural teeth, conical, tuberculate or molariform. We present the case of a 19 year-old girl who presented with a mesiodens of an unusual morphology and multiple impacted supernumerary teeth not associated with any syndrome.

  20. 狗猪鹿牙齿的高耐磨特性对比%Comparison of tribological properties of dog teeth, pig teeth and beer teeth

    Institute of Scientific and Technical Information of China (English)

    马云海; 裴高院; 王虎彪; 马圣胜; 庄健; 佟金

    2015-01-01

    As a kind of typical natural biological material, mammalian teeth have formed the optimized geometry with excellent mechanical properties after a long period of evolution, and have occupies an important position in the field of engineering bionics. Biological tribology is a new cross subject, which involves extensively, such as medicine, materials science, biology, tribology, mechanics, and is mainly divided into 2 categories i.e. human biological tribology and bionic tribology. Teeth tribology is a branch of biological tribology.The study object of modern tooth tribology is divided into 2 major categories i.e. human and animal.The research of human tooth friction is mainly concentrated in the medical field. The main purpose of the research is to master the mechanism of the friction and wear, minimize the irreversible damage of the tooth in the occlusion process and service human oral health. The research and application of animal tooth friction is mainly in engineering field, and a series of studies have been carried out in recent years. Studies on mechanical properties of the mammalian teeth mainly use nano-mechanics test and Vickers hardness test. Taking the teeth of dogs, pigs and deer as the research objects, the friction and wear behavior of the 3 different animal teeth was investigated systematically in this paper. The wear resistance of the 3 teeth surfaces was estimated by a wear tester and a roughness tester. The structure of different worn surfaces was characterized by the scanning electron microscopy (SEM), and the mechanical properties such as hardness and elastic modulus were also evaluated by using a nano-test apparatus. Hardness is the ability of material to resist the pressure of hard objects onto its surface, which is the inherent property of the material, and the tribology properties of materials depend on its hardness to a certain extent. Research results showed that wear debris peeling off from the surface of dog enamel was serious. The surface

  1. Surgical removal versus retention for the management of asymptomatic impacted wisdom teeth (Review)

    NARCIS (Netherlands)

    Mettes, T.G.; Ghaeminia, H.; Nienhuijs, M.E.L.; Perry, J.; Sanden, W.J. van der; Plasschaert, A.

    2012-01-01

    BACKGROUND: The prophylactic removal of asymptomatic impacted wisdom teeth is defined as the (surgical) removal of wisdom teeth in the absence of local disease. Impacted wisdom teeth may be associated with pathological changes, such as inflammation of the gums around the tooth, root resorption, gum

  2. Surgical removal versus retention for the management of asymptomatic disease-free impacted wisdom teeth

    NARCIS (Netherlands)

    Ghaeminia, H.; Perry, J.; Nienhuijs, M.E.L.; Toedtling, V.; Tummers, M.J.; Hoppenreijs, T.J.; Sanden, W.J.M. van der; Mettes, T.G.P.H.

    2016-01-01

    BACKGROUND: Prophylactic removal of asymptomatic disease-free impacted wisdom teeth is surgical removal of wisdom teeth in the absence of symptoms and with no evidence of local disease. Impacted wisdom teeth may be associated with pathological changes, such as pericoronitis, root resorption, gum and

  3. Histological evaluation of electrosurgery and formocresol pulpotomy techniques in primary teeth in dogs.

    Science.gov (United States)

    El-Meligy, O; Abdalla, M; El-Baraway, S; El-Tekya, M; Dean, J A

    2001-01-01

    The purpose of this study was to compare pulpal and periapical tissue reactions to electrosurgery versus formocresol pulpotomy techniques in the primary teeth of dogs. The study was conducted on 33 primary teeth of three mongrel dogs between the ages of one to three months. Each dog had three teeth treated by Formocresol Pulpotomy with Mechanical Coronal Pulp Removal (FC), three teeth treated by Electrosurgery Pulpotomy with Mechanical Coronal Pulp Removal (ES/MCPR), three teeth treated by Electrosurgery Pulpotomy with Electrosurgical Coronal Pulp Removal (ES/ECPR), and two teeth serving as untreated Controls. Dogs one, two and three were sacrificed performing the pulpotomies at two, four and six weeks, respectively. The pulp, periapical tissue and after surrounding bone were submitted to histological examination and the histological reaction was recorded. The results were fourteen out of 18 unfavorable and zero out of three favorable histological reactions occurred in the FC treated teeth. Six out of 18 unfavorable and one out of three favorable histological reactions occurred in the ES/MCPR treated teeth. Nine out of 18 unfavorable and two out of three favorable histological reactions occurred in the ES/ECPR treated teeth. One out of 18 unfavorable and zero out of three favorable histological reactions occurred in the untreated Control teeth. The conclusion of this study is that of the three experimental groups, the teeth treated by Electrosurgery Pulpotomy with either Mechanical or Electrosurgical Coronal Pulp Removal exhibited less histopathological reaction than the teeth treated by Formocresol Pulpotomy.

  4. Interventions for treating asymptomatic impacted wisdom teeth in adolescents and adults (Review)

    NARCIS (Netherlands)

    Mettes, Th.G.P.H.; Nienhuijs, M.E.L.; Sanden, W.J.M. van der; Verdonschot, E.H.A.M.; Plasschaert, A.J.M.

    2005-01-01

    BACKGROUND: The prophylactic removal of asymptomatic impacted wisdom teeth is defined as the (surgical) removal of wisdom teeth in the absence of local disease. Impacted wisdom teeth have been associated with pathological changes, such as inflammation of the gums around the tooth, root resorption, g

  5. Whole-exome sequencing analysis of supernumerary teeth occurrence in Japanese individuals.

    Science.gov (United States)

    Takahashi, Masahiro; Hosomichi, Kazuyoshi; Yamaguchi, Tetsutaro; Yano, Keisuke; Funatsu, Takahiro; Adel, Mohamed; Haga, Shugo; Maki, Koutaro; Tajima, Atsushi

    2017-01-01

    A common disorder of human dentition is the existence of supernumerary teeth. Impacted supernumerary teeth occur most frequently in the maxillary incisor area and are termed mesiodens. We conducted whole-exome sequencing of non-syndromic Japanese individuals possessing supernumerary teeth to identify genes and/or loci involved in the pathogenesis of the condition.

  6. Prevalence of impacted and supernumerary teeth in the North Indian population.

    Science.gov (United States)

    Patil, Santosh; Maheshwari, Sneha

    2014-04-01

    Dental impaction is a very frequent problem. Supernumerary teeth, or hyperdontia, are the presence of additional teeth to the normal series in the either of the dentition. The presence of impacted and/or supernumerary teeth can cause various complications. The objective of the present study was to determine the prevalence of impacted and supernumerary teeth in the North Indian population. The panoramic radiographic records of 4750 patients attending the Department of Oral Medicine and Radiology, Jodhpur Dental College General Hospital between September 2008 to December 2012 were examined for this retrospective study. The ages of the patients ranged from 8 to 72 years, with a mean of 34.6 years. A total of 798 (16.8%) patients presented with 1126 impacted teeth. Impacted canines were the most prevalent (9.7%), followed by impacted premolars (4.3%). Supernumerary teeth (1.6%) and impacted molars (1.2%) were less prevalent. Among the 842 impacted teeth, the most frequently affected teeth were the canines (56.7%), followed by premolars (27.8%), and supernumerary teeth (9.3%), while the prevalence of impacted molars was quite lower (6.2%). The most frequently impacted teeth were maxillary canines and the mesiodens were the most common supernumerary tooth. The early diagnosis of supernumerary and impacted teeth is essential to prevent malocclusion and malalignment of permanent teeth demonstrating the importance of panoramic radiographs in their detection. Key words:Impacted, supernumerary, prevalence, canines, mesiodens.

  7. Eosinophilic bronchitis-like lesion as the cause of death in a Macaca mulatta: a first case report

    Science.gov (United States)

    Christal, J.L.; Hubbard, G.B.; Dick, E.J.; Brasky, K.M.; Jagirdar, J.

    2009-01-01

    Background Eosinophilic bronchitis is a recently described, relatively benign condition in humans that is characterized by a corticosteroid-responsive chronic cough and sputum eosinophilia without the abnormalities of airway function seen in asthma. The exact cause of this condition is currently unknown, however has been associated with various occupational exposures in humans. It has also been reported to progress to irreversible airway obstruction. This disease has been reported in dogs and horses, but not in non-human primates. Methods Gross examination of an otherwise healthy 13-year-old, colony-born Macaca mulatta, which died of severe non-responsive respiratory distress revealed that the lungs were markedly inflated and moist. Results Hematoxylin and eosin-stained sections from the lungs contained widespread accumulation of eosinophils, sloughed epithelial cells, and mucus centered around bronchioles and adjacent airways. There was no evidence of mast cell infiltration of peribronchiolar smooth muscle, goblet cell hyperplasia, or basement membrane thickening. Conclusions This ruled out recurrent episodes as would be expected in asthma, favoring the diagnosis of an eosinophilic bronchitis-like lesion. We report a first case of eosinophilic bronchitis-like features in a M. mulatta. PMID:18333916

  8. Fasting induced kisspeptin signaling suppression is regulated by glutamate mediated cues in adult male rhesus macaque (Macaca mulatta).

    Science.gov (United States)

    Shamas, Shazia; Khan, Saeed-Ul-Hassan; Khan, Muhammad Yousaf; Shabbir, Nadia; Zubair, Hira; Shafqat, Saira; Wahab, Fazal; Shahab, Muhammad

    2015-08-01

    Kisspeptin signaling is suppressed by short term fasting. It has been reported that hypothalamic Kiss1 and Kiss1r mRNA expression decreased after 48h of fasting in male rhesus monkey. But the mechanism involved in the reduction of kisspeptin signaling after 48h of fasting is unknown. Recent studies have suggested the role of afferent excitatory and inhibitory pathways in the regulation of kisspeptin neurons. Therefore, this study was designed to observe the changes in the glutamate and GABA signaling during fed and 48h fasting states by performing immunofluorescence to examine the interaction of kisspeptin neurons with NR1 subunit of NMDA receptors and by performing SYBR green qRT-PCR to measure and quantify the levels of Kiss1, Kiss1r, NR1 and GAD67 mRNA in the POA and MBH of adult male rhesus macaque (Macaca mulatta) during 48h of fasting (n=2) and fed ad libitum (n=2). Plasma testosterone (pfasting. Our results clearly showed that expression of hypothalamic Kiss1, Kiss1r and NR1 mRNA was significantly (pfasting. These observations suggest that decreased kisspeptin signaling during fasting may occur due to reduction in glutamatergic inputs to kisspeptin neurons. Our results also suggest that fasting induced suppression of kisspeptin signaling is not mediated through GABAergic neurons.

  9. Neonatal imitation predicts infant rhesus macaque (Macaca mulatta) social and anxiety-related behaviours at one year

    Science.gov (United States)

    Kaburu, Stefano S. K.; Paukner, Annika; Simpson, Elizabeth A.; Suomi, Stephen J.; Ferrari, Pier F.

    2016-01-01

    The identification of early markers that predict the development of specific social trajectories is critical to understand the developmental and neurobiological underpinnings of healthy social development. We investigated, in infant rhesus macaques (Macaca mulatta), whether newborns’ capacity to imitate facial gestures is a valid predictive marker for the emergence of social competencies later in development, at one year of age. Here we first assessed whether infant macaques (N = 126) imitate lipsmacking gestures (a macaque affiliative expression) performed by a human experimenter in their first week of life. We then collected data on infants’ social interactions (aggression, grooming, and play) and self-scratching (a proxy indicator of anxiety) at 11–14 months when infants were transferred into a new enclosure with a large social group. Our results show that neonatal imitators exhibit more dominant behaviours, are less anxious, and, for males only, spend more time in play at one year old. These findings suggest that neonatal imitation may be an early predictor of infant sociality and may help identify infants at risk of neurodevelopmental social deficits. PMID:27725768

  10. Grooming-related feeding motivates macaques to groom and affects grooming reciprocity and episode duration in Japanese macaques (Macaca fuscata).

    Science.gov (United States)

    Onishi, Kenji; Yamada, Kazunori; Nakamichi, Masayuki

    2013-01-01

    Allogrooming is considered as an altruistic behavior wherein primates exchange grooming as a tradable commodity for reciprocal grooming or other commodities such as support during aggression and tolerance during co-feeding. First, we report a case of the grooming relationships of the lowest-ranking adult female in a group of Japanese macaques (Macaca fuscata). The female (Lp) had lost a portion of the fur and was groomed by higher-ranking individuals without providing reciprocal grooming or other commodities. The groomers probably fed on lice eggs from the fur of Lp more frequently than from that of other adult groomees. This suggests that grooming-related feeding (GRF) motivated many individuals to groom Lp and influenced grooming reciprocity in dyads. Second, we investigated quantitative grooming data for adult females. A high GRF rate was found to lengthen the duration of grooming, suggesting that GRF motivates groomers to groom. From these results, we proposed 2 possible reasons for groomers' sensitivity to GRF rate: (1) the nutritional benefit from GRF compensates for part of the cost of giving grooming and facilitates giving grooming and (2) groomer's sensitivity to the GRF rate maintains the efficiency of removing lice eggs and ensures the groomee's hygienic benefit in receiving grooming.

  11. Genetic variation between two Tibetan macaque (Macaca thibetana) populations in the eastern China based on mitochondrial DNA control region sequences.

    Science.gov (United States)

    Yao, Yongfang; Zhong, Lijing; Liu, Bofeng; Li, Jiayi; Ni, Qingyong; Xu, Huailiang

    2013-06-01

    Tibetan macaque (Macaca thibetana) is a threatened primate species endemic to China. Population genetic and phylogenetic analyses were conducted in 66 Tibetan individuals from Sichuan (SC), Huangshan (HS), and Fujian (FJ) based on a 477-bp fragment of mitochondrial DNA control region. Four new haplotypes were defined, and a relatively high level of genetic diversity was first observed in FJ populations (Hd = 0.7661). Notably, a continuous approximately 10 bp-fragment deletion was observed near the 5' end of the mtDNA control region of both HS and FJ populations when compared with that of SC population, and a sharing haplotype was found between the two populations, revealing a closer genetic relationship. However, significant genetic differentiation (FST = 0.8700) and more poor gene exchange (Nm < 1) had occurred among three populations. This study mainly provide a further insight into the genetic relationship between HS and FJ Tibetan macaque populations, but it may be necessary to carry out further study with extra samples from other locations in the geographic coverage of the two subspecies (M. thibetana pullus and M. thibetana huangshanensis).

  12. Influence of dominance rank and affiliation relationships on self-directed behavior in female Tibetan macaques (Macaca thibetana).

    Science.gov (United States)

    Zhang, Qi-Xin; Li, Jin-Hua; Xia, Dong-Po; Zhu, Yong; Wang, Xi; Zhang, Dao

    2014-05-01

    Self-directed behavior (SDB) is characterized as an indicator of anxiety, frustration and stress in nonhuman primates. In this study, we collected self-directed behavior data from one group of free-ranging Tibetan macaques (Macaca thibetana) at Mt. Huangshan, China (September 2012-May 2013) using a combination of behavioral sampling methods including focal animal sampling, behavioral sampling, continuous sampling and instantaneous sampling. Our results showed that females engaged in significantly higher rates of self-directed behavior when they were in proximity to dominant individuals compared to subordinate ones. Conflict losers significantly increased their SDB rates after agonistic episodes, indicating that SDB might also serve as an index of anxiety in M. thibetana. We further found that females significantly increased their SDB rates when focal individual was proximity to weakly affiliation relationship higher rank members than to strongly affiliation relationship higher rank members. If conflicts were not reconciled, the postconflict SDB rates of losers were higher when they stayed with strongly affiliation opponents; if conflicts were reconciled, victims of strongly affiliation relationships opponents engaged in more SDB rates before reconciliation than after reconciliation, while victims of moderately affiliation relationships opponents did not engaged in more SDB rates before reconciliation than after reconciliation. We conclude that both of dominance rank and affiliation relationships might both influence the SDB rates of female Tibetan macaques significantly, suggesting that SDB is not only an index of anxiety in Tibetan macaques, but also can provide a new insight into evaluation of social relationships between individuals.

  13. Analysis of immunoglobulin, complements and CRP levels in serum of captive northern pig-tailed macaques (Macaca leonina).

    Science.gov (United States)

    Zhang, Xiao-Liang; Pang, Wei; Deng, De-Yao; Lv, Long-Bao; Feng, Yue; Zheng, Yong-Tang

    2014-05-01

    The northern pig-tailed macaque (NPM,Macaca leonina) has become a widely used animal model in biomedical research. In this study, we measured serum immunoglobulin IgG, IgM, IgA, complement C3, C4 and CRP levels in 3-11 year old captive northern pig-tailed macaques using HITACHI 7600-20 automated chemistry analyzer in order to determine the influences of age and gender on these items. The results showed that serum IgA, IgM, C3 and C4 levels were not correlated with age (P>0.05), while serum IgG levels increased progressively with age (r=0.202;P=0.045). Serum IgG, IgA, IgM and C3 levels were higher in females than in males (P<0.05). Moreover, serum C3 concentration was both positively and strongly correlated with that of C4 (r=0.700; P<0.0001). This study provides basic serum immunoglobulin and complement data of captive northern pig-tailed macaques, which may prove useful for future breeding efforts and biomedical research.

  14. Intergroup variation in stable isotope ratios reflects anthropogenic impact on the Barbary macaques (Macaca sylvanus) of Gibraltar.

    Science.gov (United States)

    Schurr, Mark R; Fuentes, Agustín; Luecke, Ellen; Cortes, John; Shaw, Eric

    2012-01-01

    Interactions with humans impact many aspects of behavior and ecology in nonhuman primates. Because of the complexities of the human-nonhuman primate interface, methods are needed to quantify the effects of anthropogenic interactions, including their intensity and differential impacts between nonhuman primate groups. Stable isotopes can be used to quickly and economically assess intergroup dietary variation, and provide a framework for the development of specific hypotheses about anthropogenic impact. This study uses stable carbon and nitrogen isotope analysis to examine intraspecific variation in diet between five groups of Barbary macaques, Macaca sylvanus, in the Upper Rock Nature Reserve, Gibraltar. Analysis of hair from 135 macaques showed significant differences in δ(13)C and δ(15)N values between a group with minimal tourist contact and groups that were main tourist attractions. Because we observed no overt physiological or substantial behavioral differences between the groups, feeding ecology is the most likely cause of any differences in stable isotope ratios. Haphazard provisioning by tourists and Gibraltarians is a likely source of dietary variation between groups. Stable isotope analysis and observational data facilitate a deeper understanding of the feeding ecology of the Barbary macaques relevant to the role of an anthropogenic ecology for the species.

  15. Expression analysis of taste signal transduction molecules in the fungiform and circumvallate papillae of the rhesus macaque, Macaca mulatta.

    Directory of Open Access Journals (Sweden)

    Yoshiro Ishimaru

    Full Text Available The molecular mechanisms of the mammalian gustatory system have been examined in many studies using rodents as model organisms. In this study, we examined the mRNA expression of molecules involved in taste signal transduction in the fungiform papillae (FuP and circumvallate papillae (CvP of the rhesus macaque, Macaca mulatta, using in situ hybridization. TAS1R1, TAS1R2, TAS2Rs, and PKD1L3 were exclusively expressed in different subsets of taste receptor cells (TRCs in the FuP and CvP. This finding suggests that TRCs sensing different basic taste modalities are mutually segregated in macaque taste buds. Individual TAS2Rs exhibited a variety of expression patterns in terms of the apparent level of expression and the number of TRCs expressing these genes, as in the case of human TAS2Rs. GNAT3, but not GNA14, was expressed in TRCs of FuP, whereas GNA14 was expressed in a small population of TRCs of CvP, which were distinct from GNAT3- or TAS1R2-positive TRCs. These results demonstrate similarities and differences between primates and rodents in the expression profiles of genes involved in taste signal transduction.

  16. Individual differences in scanpaths correspond with serotonin transporter genotype and behavioral phenotype in rhesus monkeys (Macaca mulatta

    Directory of Open Access Journals (Sweden)

    Robert R Gibboni

    2009-11-01

    Full Text Available Scanpaths (the succession of fixations and saccades during spontaneous viewing contain information about the image but also about the viewer. To determine the viewer-dependent factors in the scanpaths of monkeys, we trained three adult males (Macaca mulatta to look for 3 s at images of conspecific facial expressions with either direct or averted gaze. The subjects showed significant differences on four basic scanpath parameters (number of fixations, fixation duration, saccade length, and total scanpath length when viewing the same facial expression/gaze direction combinations. Furthermore, we found differences between monkeys in feature preference and in the temporal order in which features were visited on different facial expressions. Overall, the between-subject variability was larger than the within- subject variability, suggesting that scanpaths reflect individual preferences in allocating visual attention to various features in aggressive, neutral, and appeasing facial expressions. Individual scanpath characteristics were brought into register with the genotype for the serotonin transporter regulatory gene (5-HTTLPR and with behavioral characteristics such as expression of anticipatory anxiety and impulsiveness/hesitation in approaching food in the presence of a potentially dangerous object.

  17. MaqFACS (Macaque Facial Action Coding System) can be used to document facial movements in Barbary macaques (Macaca sylvanus).

    Science.gov (United States)

    Julle-Danière, Églantine; Micheletta, Jérôme; Whitehouse, Jamie; Joly, Marine; Gass, Carolin; Burrows, Anne M; Waller, Bridget M

    2015-01-01

    Human and non-human primates exhibit facial movements or displays to communicate with one another. The evolution of form and function of those displays could be better understood through multispecies comparisons. Anatomically based coding systems (Facial Action Coding Systems: FACS) are developed to enable such comparisons because they are standardized and systematic and aid identification of homologous expressions underpinned by similar muscle contractions. To date, FACS has been developed for humans, and subsequently modified for chimpanzees, rhesus macaques, orangutans, hylobatids, dogs, and cats. Here, we wanted to test whether the MaqFACS system developed in rhesus macaques (Macaca mulatta) could be used to code facial movements in Barbary macaques (M. sylvanus), a species phylogenetically close to the rhesus macaques. The findings show that the facial movement capacity of Barbary macaques can be reliably coded using the MaqFACS. We found differences in use and form of some movements, most likely due to specializations in the communicative repertoire of each species, rather than morphological differences.

  18. Phylogenetic relationships of Malaysia's pig-tailed macaque Macaca nemestrina based on D-loop region sequences

    Science.gov (United States)

    Abdul-Latiff M. A., B.; Ampeng, A.; Yaakop, S.; Md-Zain B., M.

    2014-09-01

    Phylogenetic relationships among Malaysian pig-tailed macaques have never been established even though the data are crucial in aiding conservation plan for the species. The aims of this study is to establish the phylogenetic relationships of Macaca nemestrina in Malaysia. A total of 21 genetic samples of M. nemestrina yielding 458 bp of D-loop sequences were used in phylogenetic analyses, in addition to one sample of M. fascicularis which was used as an outgroup. Sequence character analysis revealed that D-loop locus contains 23% parsimony informative character detected among the ingroups. Further analysis indicated a clear separation between populations originating from different regions; the Malay Peninsula populations are separated from Borneo Insular population; and Perak population formed a distinctive clade within Peninsular Malaysia populations. Phylogenetic trees (NJ, MP and Bayesian) portray a consistent clustering paradigm as Borneo population was distinguished from Peninsula population (100% bootstrap value in the NJ, MP, 1.00 posterior probability in Bayesian trees). Perak's population was separated from other Peninsula populations (100% in NJ, 99% in MP and 1.00 in Bayesian). D-loop region of mtDNA is proven to be a suitable locus in studying the separation of M. nemestrina at population level. These findings are crucial in aiding the conservation management and translocation process of M. fascicularis populations in Malaysia.

  19. Associations between Parity, Hair Hormone Profiles during Pregnancy and Lactation, and Infant Development in Rhesus Monkeys (Macaca mulatta).

    Science.gov (United States)

    Dettmer, Amanda M; Rosenberg, Kendra L; Suomi, Stephen J; Meyer, Jerrold S; Novak, Melinda A

    2015-01-01

    Studies examining hormones throughout pregnancy and lactation in women have been limited to single, or a few repeated, short-term measures of endocrine activity. Furthermore, potential differences in chronic hormonal changes across pregnancy/lactation between first-time and experienced mothers are not well understood, especially as they relate to infant development. Hormone concentrations in hair provide long-term assessments of hormone production, and studying these measures in non-human primates allows for repeated sampling under controlled conditions that are difficult to achieve in humans. We studied hormonal profiles in the hair of 26 female rhesus monkeys (Macaca mulatta, n=12 primiparous), to determine the influences of parity on chronic levels of cortisol (hair cortisol concentration, HCC) and progesterone (hair progesterone concentration, HPC) during early- to mid-pregnancy (PREG1), in late pregnancy/early lactation (PREG2/LACT1), and in peak lactation (LACT2). We also assessed infants' neurobehavioral development across the first month of life. After controlling for age and stage of pregnancy at the first hair sampling period, we found that HCCs overall peaked in PREG2/LACT1 (p=0.02), but only in primiparous monkeys (ppregnancy and lactation for all monkeys (phormonal profiles and infant development. These effects may, in part, reflect differential reproductive and maternal effort in mothers with varied caretaking experience. In addition, infant exposure to relatively higher levels of maternal cortisol during the late fetal and early postnatal periods is predictive of poorer developmental outcomes.

  20. Complete Taiwanese Macaque (Macaca cyclopis) Mitochondrial Genome: Reference-Assisted de novo Assembly with Multiple k-mer Strategy.

    Science.gov (United States)

    Huang, Yu-Feng; Midha, Mohit; Chen, Tzu-Han; Wang, Yu-Tai; Smith, David Glenn; Pei, Kurtis Jai-Chyi; Chiu, Kuo Ping

    2015-01-01

    The Taiwanese (Formosan) macaque (Macaca cyclopis) is the only nonhuman primate endemic to Taiwan. This primate species is valuable for evolutionary studies and as subjects in medical research. However, only partial fragments of the mitochondrial genome (mitogenome) of this primate species have been sequenced, not mentioning its nuclear genome. We employed next-generation sequencing to generate 2 x 90 bp paired-end reads, followed by reference-assisted de novo assembly with multiple k-mer strategy to characterize the M. cyclopis mitogenome. We compared the assembled mitogenome with that of other macaque species for phylogenetic analysis. Our results show that, the M. cyclopis mitogenome consists of 16,563 nucleotides encoding for 13 protein-coding genes, 2 ribosomal RNAs and 22 transfer RNAs. Phylogenetic analysis indicates that M. cyclopis is most closely related to M. mulatta lasiota (Chinese rhesus macaque), supporting the notion of Asia-continental origin of M. cyclopis proposed in previous studies based on partial mitochondrial sequences. Our work presents a novel approach for assembling a mitogenome that utilizes the capabilities of de novo genome assembly with assistance of a reference genome. The availability of the complete Taiwanese macaque mitogenome will facilitate the study of primate evolution and the characterization of genetic variations for the potential usage of this species as a non-human primate model for medical research.

  1. Cashing out: The decisional flexibility of uncertainty responses in rhesus macaques (Macaca mulatta) and humans (Homo sapiens).

    Science.gov (United States)

    Zakrzewski, Alexandria C; Perdue, Bonnie M; Beran, Michael J; Church, Barbara A; Smith, J David

    2014-10-01

    Researchers are exploring whether animals share with humans something like a metacognitive capacity. Though some results point to human-animal continuities in this domain, they face the dominant criticism that animals' performances might be associative. A persistent problem is that animal-metacognition paradigms present static environments of risk and reward that may foster inflexible and conditioned responding. Those environments do not challenge animals to show the flexibility in their decision strategies that could indicate an antecedent capacity to metacognition. Accordingly, we tested macaques and humans on an uncertainty-monitoring paradigm in which risk changed dynamically. Participants classified stimuli of different difficulties while also choosing when to use a cashout response to collect the accumulated rewards that would be forfeit on a discrimination error. Macaques (Macaca mulatta) and humans flexibly adjusted their decision criteria to achieve appropriate protection against the cost of error that could differ depending on trial difficulty and the number of rewards at risk. In particular, monkeys widened their cashout-response region as their accumulated rewards increased, providing more protection against a more costly error. These findings demonstrate a new continuity between humans' and animals' uncertainty systems. They reveal a calibration by macaques of present risk to trial difficulty tolerated. They show that animals' uncertainty-monitoring and risk-management systems have substantial trial-by-trial flexibility.

  2. Behavioural and pharmacokinetic studies in the monkey (Macaca mulatta) with diazepam, nordiazepam and related 1,4-benzodiazepines.

    Science.gov (United States)

    Curry, S H; Whelpton, R; Nicholson, A N; Wright, C M

    1977-11-01

    1. Behavioural activity (delayed differentiation and spatial delayed alternation) and pharmacokinetics of diazepam and its metabolites, N-desmethyldiazepam (nordiazepam), 3-hydroxydiazepam (temazepam) and 3-hydroxy-N-desmethyldiazepam (oxazepam), and of dipotassium clorazepate (clorazepate), were studied in the monkey (Macaca mulatta). Diazepam and its metabolites (1.8 and 3.0 mg/kg) and clorazepate (2.6 and 4.3 mg/kg) were given by intraperitoneal injection. 2. Hydroxylation of diazepam (temazepam and oxazepam) led to a loss of, or a considerable reduction in, behavioural activity, whereas activity was preserved, though modified, by demethylation (nordiazepam). It was not possible to establish change in behaviour at specific time intervals after clorazepate, but combined performance data revealed an effect. 3. The maximum mean plasma concentrations of diazepam, temazepam, oxazepam and clorazepate were observed at 0.5 h, and the maximum mean plasma concentration of nordiazepam was observed at 1 hour. Plasma concentrations of nordiazepam were the highest and decreased monoexponentially. Plasma concenqrations of the other drugs declined rapidly at first but more slowly later, and these data were analysed as biexponential models. In the analysis for metabolites, nordiazepam reached measurable levels after the injection of diazepam and clorazepate. 4. It is suggested that differences in the effects of closely related benzodiazepines may not be due solely to their plasma pharmacokinetic properties, but may arise from differences in their intrinsic activity.

  3. Rhesus monkeys (Macaca mulatta) discriminate between knowing and not knowing and collect information as needed before acting.

    Science.gov (United States)

    Hampton, Robert R; Zivin, Aaron; Murray, Elisabeth A

    2004-10-01

    Humans use memory awareness to determine whether relevant knowledge is available before acting, as when we determine whether we know a phone number before dialing. Such metacognition, or thinking about thinking, can improve selection of appropriate behavior. We investigated whether rhesus monkeys ( Macaca mulatta) are capable of a simple form of metacognitive access to the contents of short-term memory. Monkeys chose among four opaque tubes, one of which concealed food. The tube containing the reward varied randomly from trial to trial. On half the trials the monkeys observed the experimenter baiting the tube, whereas on the remaining trials their view of the baiting was blocked. On each trial, monkeys were allowed a single chance to select the tube containing the reward. During the choice period the monkeys had the opportunity to look down the length of each tube, to determine if it contained food. When they knew the location of the reward, most monkeys chose without looking. In contrast, when ignorant, monkeys often made the effort required to look, thereby learning the location of the reward before choosing. Looking improved accuracy on trials on which monkeys had not observed the baiting. The difference in looking behavior between trials on which the monkeys knew, and trials on which they were ignorant, suggests that rhesus monkeys discriminate between knowing and not knowing. This result extends similar observations made of children and apes to a species of Old World monkey, suggesting that the underlying cognitive capacities may be widely distributed among primates.

  4. Large-scale analysis of Macaca fascicularis transcripts and inference of genetic divergence between M. fascicularis and M. mulatta

    Directory of Open Access Journals (Sweden)

    Sugano Sumio

    2008-02-01

    Full Text Available Abstract Background Cynomolgus macaques (Macaca fascicularis are widely used as experimental animals in biomedical research and are closely related to other laboratory macaques, such as rhesus macaques (M. mulatta. We isolated 85,721 clones and determined 9407 full-insert sequences from cynomolgus monkey brain, testis, and liver. These sequences were annotated based on homology to human genes and stored in a database, QFbase http://genebank.nibio.go.jp/qfbase/. Results We found that 1024 transcripts did not represent any public human cDNA sequence and examined their expression using M. fascicularis oligonucleotide microarrays. Significant expression was detected for 544 (51% of the unidentified transcripts. Moreover, we identified 226 genes containing exon alterations in the untranslated regions of the macaque transcripts, despite the highly conserved structure of the coding regions. Considering the polymorphism in the common ancestor of cynomolgus and rhesus macaques and the rate of PCR errors, the divergence time between the two species was estimated to be around 0.9 million years ago. Conclusion Transcript data from Old World monkeys provide a means not only to determine the evolutionary difference between human and non-human primates but also to unveil hidden transcripts in the human genome. Increasing the genomic resources and information of macaque monkeys will greatly contribute to the development of evolutionary biology and biomedical sciences.

  5. Generalization hypothesis of abstract-concept learning: learning strategies and related issues in Macaca mulatta, Cebus apella, and Columba livia.

    Science.gov (United States)

    Wright, Anthony A; Katz, Jeffrey S

    2007-11-01

    The generalization hypothesis of abstract-concept learning was tested with a meta-analysis of rhesus monkeys (Macaca mulatta), capuchin monkeys (Cebus apella), and pigeons (Columba livia) learning a same/different (S/D) task with expanding training sets. The generalization hypothesis states that as the number of training items increases, generalization from the training pairs will increase and could explain the subjects' accurate novel-stimulus transfer. By contrast, concept learning is learning the relationship between each pair of items; with more training items subjects learn more exemplars of the rule and transfer better. Having to learn the stimulus pairs (the generalization hypothesis) would require more training as the set size increases, whereas learning the concept might require less training because subjects would be learning an abstract rule. The results strongly support concept or rule learning despite severely relaxing the generalization-hypothesis parameters. Thus, generalization was not a factor in the transfer from these experiments, adding to the evidence that these subjects were learning the S/D abstract concept.

  6. Tracking down human contamination in ancient human teeth

    DEFF Research Database (Denmark)

    Sampietro, María Lourdes; Gilbert, M Thomas P; Lao, Oscar

    2006-01-01

    , washing, and subsequent anthropological and genetic study of 23 Neolithic remains excavated from Granollers (Barcelona, Spain) and searched for their presence among the 572 clones generated during the aDNA analyses of teeth from these samples. Of the cloned sequences, 17.13% could be unambiguously...... identified as contaminants, with those derived from the people involved in the retrieval and washing of the remains present in higher frequencies than those of the anthropologist and genetic researchers. This finding confirms, for the first time, previous hypotheses that teeth samples are most susceptible......DNA sequences can be used to support data authenticity is misleading in scenarios where the presence of old contaminant sequences is possible. We argue therefore that the typing of those involved in the manipulation of the ancient human specimens is critical in order to ensure that generated results...

  7. [Endodontically treated teeth. Success--failure. Endorestorative treatment plan].

    Science.gov (United States)

    Zabalegui, B

    1990-01-01

    More and more often the general dentist is finding the presence of endodontically treated teeth during his treatment planning procedure. He has to ask himself if the endo-treated tooth functions and will continue to function function successfully, when deciding which final endo-restorative procedure to apply. For this reason the dentist or the endodontist with whom he works should clinically evaluate these teeth, establish a diagnostic criteria of their success or failure and a treatment plan according to the prognosis. The purpose of this article is to offer an organized clinical view of the steps to follow when evaluating an endodontically treated tooth and how to establish a final endo-restorative plan.

  8. Teeth Grinding: Is Emotional Stability related to Bruxism?

    Science.gov (United States)

    Sutin, Angelina R.; Terracciano, Antonio; Ferrucci, Luigi; Costa, Paul T.

    2010-01-01

    This study examines the association between personality traits and bruxism, the repetitive grinding or clenching of teeth. Community-dwelling participants (N = 470) had a comprehensive oral examination by a dentist and completed a dental history and personality questionnaires. Consistent with the literature on state anxiety and depression as antecedents of bruxism, Neuroticism-related traits were associated with self-reported teeth grinding. These traits were also associated with other oral complaints often associated with anxiety (jaw clicks, difficulty chewing food, and dry mouth), but not with more general oral health complaints (unhealthy gums, bleeding gums, and canker sores) or with dentist-assessed occlusal wear or tongue indentations. This study provides evidence for the association between Neuroticism and bruxism and other stress-related oral health symptoms. PMID:20835403

  9. Odontomas--silent tormentors of teeth eruption, shedding and occlusion.

    Science.gov (United States)

    Kulkarni, Vinaya Kumar; Deshmukh, Jeevanand; Banda, Naveen Reddy; Banda, Vanaja Reddy

    2012-12-14

    Odontomas are the most common odontogenic tumours of the jaws, characterised by their slow growth and non-aggressive behaviour. They usually remain asymptomatic, and are diagnosed on routine radiographs. Clinically, they are often associated with delayed eruption or impaction of permanent teeth and retained primary teeth. The purpose of this paper is to review the literature and report two cases of odontomas. In the first case, a compound odontoma was associated with an unerupted maxillary permanent right central incisor, in an 11-year-old boy. In the second case, a 12-year-old girl had retained mandibular primary left central incisor and its unerupted successor was associated with a compound odontoma, a site considered rare for compound odontoma to occur. The clinical features, diagnosis and treatment of these cases have been discussed.

  10. Teeth Grinding: Is Emotional Stability related to Bruxism?

    Science.gov (United States)

    Sutin, Angelina R; Terracciano, Antonio; Ferrucci, Luigi; Costa, Paul T

    2010-06-01

    This study examines the association between personality traits and bruxism, the repetitive grinding or clenching of teeth. Community-dwelling participants (N = 470) had a comprehensive oral examination by a dentist and completed a dental history and personality questionnaires. Consistent with the literature on state anxiety and depression as antecedents of bruxism, Neuroticism-related traits were associated with self-reported teeth grinding. These traits were also associated with other oral complaints often associated with anxiety (jaw clicks, difficulty chewing food, and dry mouth), but not with more general oral health complaints (unhealthy gums, bleeding gums, and canker sores) or with dentist-assessed occlusal wear or tongue indentations. This study provides evidence for the association between Neuroticism and bruxism and other stress-related oral health symptoms.

  11. Study Of Gear Teeth Distortions Due To Heat Treatment

    Directory of Open Access Journals (Sweden)

    V. Khade

    2015-02-01

    Full Text Available Abstract The work aims to study the distortion occurred due to heat treatment on the Gear teeth. The paper studies various causes of distortion control techniques to eliminate distortion which includes changes in design selection of material heat treatment process mainly due to quenching that includes cooling rates quenching mediums fixtures. An experimental study and results conducted for the effects of the distortion on the Gear teeth and to reduce the distortion with certain changes design modification resulting in shape amp size changes phase changes changes in hardness microstructure and residual stresses. It is observed that adequate velocity of quench oil around the component to be heat treated ensures uniform amp desired cooling rate as per heat treatment cycle. Modification in design of baffles achieved the adequate velocity and minimization of distortion. Also Fixtures for holding finished parts or assemblies during heat treatment may be either support or restraint type to control dimensional relations during aging.

  12. Early diagnosis of teeth erosion using polarized laser speckle imaging

    Science.gov (United States)

    Nader, Christelle Abou; Pellen, Fabrice; Loutfi, Hadi; Mansour, Rassoul; Jeune, Bernard Le; Brun, Guy Le; Abboud, Marie

    2016-07-01

    Dental erosion starts with a chemical attack on dental tissue causing tooth demineralization, altering the tooth structure and making it more sensitive to mechanical erosion. Medical diagnosis of dental erosion is commonly achieved through a visual inspection by the dentist during dental checkups and is therefore highly dependent on the operator's experience. The detection of this disease at preliminary stages is important since, once the damage is done, cares become more complicated. We investigate the difference in light-scattering properties between healthy and eroded teeth. A change in light-scattering properties is observed and a transition from volume to surface backscattering is detected by means of polarized laser speckle imaging as teeth undergo acid etching, suggesting an increase in enamel surface roughness.

  13. ESR measurements of background doses in teeth of Japanese residents

    Energy Technology Data Exchange (ETDEWEB)

    Toyoda, S., E-mail: toyoda@dap.ous.ac.jp [Department of Applied Physics, Okayama University of Science, Okayama (Japan); Kondo, A. [Department of Applied Physics, Okayama University of Science, Okayama (Japan); Zumadilov, K.; Hoshi, M. [Research Institute of Radiation Biology and Medicine, Hiroshima University, Hiroshima (Japan); Miyazawa, C. [Deparment of Dentistry, Ohu University, Fukushima (Japan); Ivannikov, A. [Medical Radiological Research Center, Obninsk (Russian Federation)

    2011-09-15

    The background doses for the teeth of Japanese residents were obtained by electron spin resonance (ESR) method. The doses obtained from 77 of 92 samples are less than 100 mGy while the doses of the other samples are high up to 250 mGy. The doses for buccal part of the teeth are higher than lingual part possibly due to contributions from dental X ray examination. A positive correlation was found between the ages of the donors and the obtained doses. The averaged annual ESR dose was calculated to be 0.87 mGy/y. These doses have to be considered in actual retrospective dosimetry studies for possible radiation accidents. The statistically significant critical level for Japanese residents would be about 200 mGy for individual doses and about 100 mGy for averaged group doses for {alpha} = 5% for those with ages older than 50.

  14. Sealants for preventing dental decay in the permanent teeth

    DEFF Research Database (Denmark)

    Ahovuo-Saloranta, Anneli; Forss, Helena; Walsh, Tanya

    2013-01-01

    in preventing caries in children and adolescents when compared to no sealants. Their effectiveness may be related to the caries prevalence in the population. OBJECTIVES: To compare the effects of different types of fissure sealants in preventing caries in permanent teeth in children and adolescents. SEARCH...... of age. DATA COLLECTION AND ANALYSIS: Two review authors independently screened search results, extracted data and assessed trial quality. We calculated the odds ratio (OR) for caries or no caries on occlusal surfaces of permanent molar teeth. For trials with a split-mouth design, the Becker...... or the baseline caries prevalence.- Resin-based sealant compared with no sealant: Compared to control without sealant, second or third or fourth generation resin-based sealants prevented caries in first permanent molars in children aged 5 to 10 years (at 2 years of follow-up odds ratio (OR) 0.12, 95% confidence...

  15. Coronectomy of two neighbouring ankylosed mandibular teeth: A case report

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    Biočanin Vladimir

    2014-01-01

    Full Text Available Introduction. Intentional partial odontectomy or coronectomy is primarily advocated in situations with intimate relationships between the roots of the tooth indicated for extraction and the inferior alveolar nerve (IAN. The aim of this report was to present a patient with two neighbouring infraoccluded teeth in the right mandible indicated for extraction prior to prosthetic rehabilitation, which were coronectomied as to prevent injuring of the IAN and causing iatrogenic fracture of the mandibular body. Case report. Coronectomy of both teeth was performed as recommended in the literature. The patient had no special discomfort after the operation or deficit in sensitive nerve function, and the wound healed uneventfully. The patient was followed regularly during a 2- year period. Conclusion. The presented case suggests coronectomy as quite beneficial solution for avoiding serious problems (injuring of the IAN and possible fracture of the mandible and making feasible forthcoming prosthetic rehabilitation. [Projekat Ministarstva nauke Republike Srbije, br. 175021

  16. Pulp tissue from primary teeth: new source of stem cells

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    Paloma Dias Telles

    2011-06-01

    Full Text Available SHED (stem cells from human exfoliated deciduous teeth represent a population of postnatal stem cells capable of extensive proliferation and multipotential differentiation. Primary teeth may be an ideal source of postnatal stem cells to regenerate tooth structures and bone, and possibly to treat neural tissue injury or degenerative diseases. SHED are highly proliferative cells derived from an accessible tissue source, and therefore hold potential for providing enough cells for clinical applications. In this review, we describe the current knowledge about dental pulp stem cells and discuss tissue engineering approaches that use SHED to replace irreversibly inflamed or necrotic pulps with a healthy and functionally competent tissue that is capable of forming new dentin.

  17. Sealants for preventing dental decay in the permanent teeth

    DEFF Research Database (Denmark)

    Ahovuo-Saloranta, Anneli; Forss, Helena; Walsh, Tanya;

    2013-01-01

    or the baseline caries prevalence.- Resin-based sealant compared with no sealant: Compared to control without sealant, second or third or fourth generation resin-based sealants prevented caries in first permanent molars in children aged 5 to 10 years (at 2 years of follow-up odds ratio (OR) 0.12, 95% confidence...... 2012). SELECTION CRITERIA: Randomised or quasi-randomised controlled trials of at least 12 months duration comparing sealants for preventing caries of occlusal or approximal surfaces of premolar or molar teeth with no sealant or different type of sealant in children and adolescents under 20 years...... of age. DATA COLLECTION AND ANALYSIS: Two review authors independently screened search results, extracted data and assessed trial quality. We calculated the odds ratio (OR) for caries or no caries on occlusal surfaces of permanent molar teeth. For trials with a split-mouth design, the Becker...

  18. Maturogenesis of non-vital immature permanent teeth.

    Science.gov (United States)

    Kalaskar, Ritesh R; Kalaskar, Ashita R

    2013-04-01

    Pulpal necrosis in young permanent teeth often results in teeth with open apex, thin root walls and poor crown root ratio. Out of the available treatment options maturogenesis has been the most conservative option that exploits full potential of pulp for dentin deposition. Maturogenesis involves disinfecting the root canal system followed by stimulation of blood clot from the periapical tissue, which provides a matrix into which the cell could grow and sealing the coronal excess. In the present case report, tri antibacterial paste (3 Mix) was used as an intracanal medicament that proved successful in stimulating vital pulp cells of the periapical region for maturogenesis. Five months radiograph follow-up showed thickening of lateral dentinal walls, which progress until 15 months resulting in apical closure, thickening of lateral dentinal walls and increase root length.

  19. Maturogenesis of non-vital immature permanent teeth

    Directory of Open Access Journals (Sweden)

    Ritesh R Kalaskar

    2013-01-01

    Full Text Available Pulpal necrosis in young permanent teeth often results in teeth with open apex, thin root walls and poor crown root ratio. Out of the available treatment options maturogenesis has been the most conservative option that exploits full potential of pulp for dentin deposition. Maturogenesis involves disinfecting the root canal system followed by stimulation of blood clot from the periapical tissue, which provides a matrix into which the cell could grow and sealing the coronal excess. In the present case report, tri antibacterial paste (3 Mix was used as an intracanal medicament that proved successful in stimulating vital pulp cells of the periapical region for maturogenesis. Five months radiograph follow-up showed thickening of lateral dentinal walls, which progress until 15 months resulting in apical closure, thickening of lateral dentinal walls and increase root length.

  20. Handling characteristics of resin composites in posterior teeth.

    Science.gov (United States)

    Ferrari, M; Kugel, G

    1998-09-01

    In the last 10 years, tremendous improvements in strength and shade selection for resin composites have been achieved. Also, a new generation of enamel-dentin bonding systems has been developed, and patient expectations of esthetic treatment have risen. Several techniques are available for restoring posterior teeth. When a caries lesion is limited, a direct esthetic restoration is indicated. Essential elements for obtaining good, long-term clinical results for direct esthetic restorations of posterior teeth are: (1) cavity preparation; (2) knowledge of the characteristics of the three dental substrates; (3) rubber dam use and matrix and wedge placement; (4) correct use of the enamel-dentin bonding system; (5) proper selection of the resin composite material; (6) use of the multilayering technique; (7) finishing and polishing procedures; and (8) maintenance of the restoration.

  1. Management of third molar teeth from an endodontic perspective

    Directory of Open Access Journals (Sweden)

    Hany Mohamed Aly Ahmed

    2012-01-01

    Full Text Available Third molar teeth are subject to many dental complications because of their most posterior location, aberrant occlusal anatomy and abnormal eruption patterns. Owing to these anatomical limitations, their extraction remains the treatment of choice for many dental practitioners. Despite being a common dental procedure, minimum intervention and retaining every functional component of the dental arch are of prime importance in contemporary dental practice. As such, this review aims to discuss the application of this conservative approach on third molar teeth from an endodontic perspective. The internal and external root anatomy of maxillary and mandibular third molars and their relation to the surrounding vital structures are described. These anatomical landmarks are then correlated to the decision making for endodontic treatment strategies of third molars. In addition, the recommended guidelines that should be followed while commencing endodontic treatment in third molars are outlined.

  2. A CASE OF LOWER ANTERIOR PRIMARY TEETH FUSION

    Directory of Open Access Journals (Sweden)

    Noni Nurseni

    2006-04-01

    Full Text Available Dental fusion is the most common problem seen in the primary dentition. The incidence of dental fusion was approximately 0.5% for deciduous dentition and 0.1% for permanent dentition. Fusion may be complete or incomplete. Its etiology was related to genetic or local factor. These anomalies could result in dental caries, esthetic problem, periodontal disease, dental malocclusion, and hypodontia in permanent dentition. Treatment of fused teeth depends on the location and extent of fusion. This report describes an incomplete dental fusion with dentinal caries occurred on 72 and 73 while 32 was agenesis. The purpose of the treatment was to improve the esthetic performance and subsequently to keep the teeth until the exfoliation time. After the restoration of 72 and 73, the patient feels satisfied.

  3. Recurrent periodontal abscess associated with "teeth as a tool"

    Directory of Open Access Journals (Sweden)

    G Subraya Bhat

    2012-01-01

    Full Text Available We report an unusual case of recurrent periodontal abscess in a 31-year-old male electrician due to his habit of using his teeth as a tool for stripping electrical wires. The patient was not aware of the consequences of this habit. Clinically, there was presence of moderate depth of periodontal pocket around the tooth and, radiographically, there was a vertical defect mesial to the involved teeth. The patient was educated about the consequences of his habit and surgical treatment was undertaken. A papilla preservation flap with regenerative periodontal surgical procedure was done, orthodontic and restorative treatment was planned at the follow-up. This case highlights the importance of eliciting a proper and complete personal history, including occupational details. In our patient these details helped us correlate the destruction of the periodontium to the unusual etiology.

  4. Genotoxic effect of formocresol pulp therapy of deciduous teeth.

    Science.gov (United States)

    Lucas Leite, Ana Catarina Gaioso; Rosenblatt, Aronita; da Silva Calixto, Merilane; da Silva, Cirlene Maria; Santos, Neide

    2012-08-30

    To investigate whether formocresol, in Buckley's original formulation, used for pulp therapy of deciduous teeth, can have a genotoxic effect. Genotoxicity was tested in lymphocyte cultures from the peripheral blood of children aged 5-10y, in Recife, Pernambuco, Brazil. This was a case-control study. The sample comprised 40 children who had primary teeth with non-vital pulps. Two venous blood samples (6-8ml) were collected from each child, the first prior to pulp therapy (control group) and the second 24h after pulp therapy (experimental group). Lymphocyte cultures were grown in 78% RPMI 1640 medium, 20% fetal bovine serum, 2% phytohemagglutinin. The lymphocytes were assessed for chromosomal aberrations; each sample involved analysis of 100 metaphases. There was a statistically significant difference between the control and treated groups for the isochromatid gap (pformocresol in pediatric dentistry is recommended. Copyright © 2012 Elsevier B.V. All rights reserved.

  5. Supernumerary Teeth in Primary Dentition and Early Intervention: A Series of Case Reports

    Science.gov (United States)

    Bahadure, Rakesh N.; Thosar, Nilima; Jain, Eesha S.; Kharabe, Vidhi; Gaikwad, Rahul

    2012-01-01

    Supernumerary teeth are considered as one of the most significant dental anomalies during the primary and early mixed dentition stages. They are of great concern to the dentists and parents because of the eruption, occlusal, and esthetic problems they can cause. Supernumerary teeth occur more frequently in the permanent dentition but rarely in primary dentition. Mesiodens is the most common type of supernumerary teeth but rarely seen in lower arch. Early recognition and diagnosis of supernumerary teeth is important to prevent further complications in permanent dentition. Four cases of supernumerary teeth with mesiodens in upper and lower arch in primary dentition and their management have been discussed. PMID:22888456

  6. Supernumerary Teeth in Primary Dentition and Early Intervention: A Series of Case Reports

    Directory of Open Access Journals (Sweden)

    Rakesh N. Bahadure

    2012-01-01

    Full Text Available Supernumerary teeth are considered as one of the most significant dental anomalies during the primary and early mixed dentition stages. They are of great concern to the dentists and parents because of the eruption, occlusal, and esthetic problems they can cause. Supernumerary teeth occur more frequently in the permanent dentition but rarely in primary dentition. Mesiodens is the most common type of supernumerary teeth but rarely seen in lower arch. Early recognition and diagnosis of supernumerary teeth is important to prevent further complications in permanent dentition. Four cases of supernumerary teeth with mesiodens in upper and lower arch in primary dentition and their management have been discussed.

  7. Supernumerary teeth in primary dentition and early intervention: a series of case reports.

    Science.gov (United States)

    Bahadure, Rakesh N; Thosar, Nilima; Jain, Eesha S; Kharabe, Vidhi; Gaikwad, Rahul

    2012-01-01

    Supernumerary teeth are considered as one of the most significant dental anomalies during the primary and early mixed dentition stages. They are of great concern to the dentists and parents because of the eruption, occlusal, and esthetic problems they can cause. Supernumerary teeth occur more frequently in the permanent dentition but rarely in primary dentition. Mesiodens is the most common type of supernumerary teeth but rarely seen in lower arch. Early recognition and diagnosis of supernumerary teeth is important to prevent further complications in permanent dentition. Four cases of supernumerary teeth with mesiodens in upper and lower arch in primary dentition and their management have been discussed.

  8. Isolation and Culture of Postnatal Stem Cells from Deciduous Teeth

    OpenAIRE

    Olávez, Daniela; Facultad de Odontología Universidad de Los Andes; Salmen, Siham; Instituto de Inmunología Clínica, Universidad de Los Andes.; Padrón, Karla; Facultad de Odontología. Univerisdad de Los Andes.; Lobo, Carmine; Facultad de Odontología. Univerisdad de Los Andes.; Díaz, Nancy; Facultad de Odontología, Universidad de Los Andes.; Berrueta, Lisbeth; Doctora en Inmunología por Instituto Venezolano de Investigaciones Científicas (IVIC). Instituto de Inmunología Clínica, Facultad de Medicina, Universidad de Los Andes, Venezuela.; Solorzanio, Eduvigis; Facultad de Odontología, Universidad de Los Andes.

    2014-01-01

    Background: Currently, degenerative diseases represent a public health problem; therefore, the development and implementation of strategies to fully or partially recover of damaged tissues has a special interest in the biomedical field. Therapeutic strategies based on mesenchymal stem cells transplantation from dental pulp have been proposed as an alternative. Purpose: To develop a mesenchymal stem cells culture isolated from dental pulp of deciduous teeth. Methods: The mesenchymal stem cells...

  9. Rehabilitation of teeth with root canal treatment. Multidisciplinary approach

    OpenAIRE

    Flores Concha, Pompeyo H.; Residente 3° año, Segunda Especialidad en Rehabilitación Oral, UNMSM.; Canales Huarhua, Johnny; Residente 2°año, Segunda Especialidad en Periodoncia, UNMSM.; García Linares, Sixto; Especialidad en Periodoncia y Coordinador de Posgrado en Periodoncia, UNMSM.

    2014-01-01

    This clinical case details the teeth reconstruction and root canal retreatment, with recovery of the lost biological space invaded by maladjusted crowns and its subsequent reconstruction with fiberglass preformed poles for the cementation of splinted crowns by the decrease of the crown-root proportion. It is concluded that we must take into account the amount of remaining dental tissue, the periodontal status (biological width), the aesthetic requirements, the root morphology, the location of...

  10. Multiple unerupted teeth with amelogenesis imperfecta in siblings.

    Science.gov (United States)

    Hegde, Shruthi

    2012-05-01

    Amelogenesis imperfecta encompasses a group of inherited abnormalities that are generally considered to primarily affect the formation and/or calcification of enamel. This case report describes the unusual presentation of amelogenesis imperfecta in siblings as multiple unerupted teeth, multiple pulpal calcifications, and multiple dilacerations of roots along with the defect in the enamel. The intent of our report is to highlight a rare co-occurrence of amelogenesis imperfecta with multiple morphologic alterations in siblings.

  11. Multiple Unerupted Teeth with Amelogenesis Imperfecta in Siblings

    Directory of Open Access Journals (Sweden)

    Shruthi Hegde

    2012-01-01

    Full Text Available Amelogenesis imperfecta encompasses a group of inherited abnormalities that are generally considered to primarily affect the formation and/or calcification of enamel. This case report describes the unusual presentation of amelogenesis imperfecta in siblings as multiple unerupted teeth, multiple pulpal calcifications, and multiple dilacerations of roots along with the defect in the enamel. The intent of our report is to highlight a rare co-occurrence of amelogenesis imperfecta with multiple morphologic alterations in siblings.

  12. Prevalence, etiology, diagnosis, treatment and complications of supernumerary teeth

    OpenAIRE

    Ata-Ali Mahmud, Fadi; Ata-Ali Mahmud, Francisco Javier; Peñarrocha Oltra, David; Peñarrocha Diago, Miguel

    2014-01-01

    The aim of this article was to review the literature on supernumerary teeth, analyzing their prevalence, etiology, diagnosis, treatment and possible complications. An electronic search was made in the Pubmed-Medline database up to January 2014 using the key search terms “multiple supernumerary teeth” (n=279), “prevalence supernumerary teeth” (n=361), and “supernumerary teeth” (n=2412). In addition to the articles initially identified, others were included in the review proceeding from a manua...

  13. Isolation and Culture of Postnatal Stem Cells from Deciduous Teeth

    OpenAIRE

    Olávez, Daniela; Facultad de Odontología Universidad de Los Andes; Salmen, Siham; Instituto de Inmunología Clínica, Universidad de Los Andes.; Padrón, Karla; Facultad de Odontología. Univerisdad de Los Andes.; Lobo, Carmine; Facultad de Odontología. Univerisdad de Los Andes.; Díaz, Nancy; Facultad de Odontología, Universidad de Los Andes.; Berrueta, Lisbeth; Doctora en Inmunología por Instituto Venezolano de Investigaciones Científicas (IVIC). Instituto de Inmunología Clínica, Facultad de Medicina, Universidad de Los Andes, Venezuela.; Solorzanio, Eduvigis; Facultad de Odontología, Universidad de Los Andes.

    2014-01-01

    Background: Currently, degenerative diseases represent a public health problem; therefore, the development and implementation of strategies to fully or partially recover of damaged tissues has a special interest in the biomedical field. Therapeutic strategies based on mesenchymal stem cells transplantation from dental pulp have been proposed as an alternative. Purpose: To develop a mesenchymal stem cells culture isolated from dental pulp of deciduous teeth. Methods: The mesenchymal stem cells...

  14. DIGITAL GEOMETRIC MODELLING OF TEETH PROFILE BY USING CAD METHODOLOGY

    Directory of Open Access Journals (Sweden)

    Krzysztof TWARDOCH

    2014-03-01

    Full Text Available This article is devoted to the problem of properly defining the spatial model of tooth profile with CAD methodologies. Moved by the problem of the accuracy of the mapping defined curves describing the geometry of the teeth. Particular attention was paid to precise geometric modeling involute tooth profile, which has a significant influence on the process of identifying the mesh stiffness for tests performed on the dynamic phenomena occurring in the gear transmission systems conducted using dynamic models

  15. Smooth surface glass ionomer restoration for primary teeth.

    Science.gov (United States)

    Killian, C M; Croll, T P

    1991-01-01

    Glass ionomer restorative cement offers the clinician an alternative to bonded composite resin for restoration of certain lesions in primary teeth. This article details a step-by-step procedure for restoration of a smooth surface carious lesion in a primary incisor using an encapsulated glass ionomer restorative material and reviews advantages and limitations of the cement. A light-hardened glass ionomer liner/base that has proven useful as an enamel and dentin restorative is also described.

  16. Stable isotope ratios in hair and teeth reflect biologic rhythms.

    Directory of Open Access Journals (Sweden)

    Otto Appenzeller

    Full Text Available Biologic rhythms give insight into normal physiology and disease. They can be used as biomarkers for neuronal degenerations. We present a diverse data set to show that hair and teeth contain an extended record of biologic rhythms, and that analysis of these tissues could yield signals of neurodegenerations. We examined hair from mummified humans from South America, extinct mammals and modern animals and people, both healthy and diseased, and teeth of hominins. We also monitored heart-rate variability, a measure of a biologic rhythm, in some living subjects and analyzed it using power spectra. The samples were examined to determine variations in stable isotope ratios along the length of the hair and across growth-lines of the enamel in teeth. We found recurring circa-annual periods of slow and fast rhythms in hydrogen isotope ratios in hair and carbon and oxygen isotope ratios in teeth. The power spectra contained slow and fast frequency power, matching, in terms of normalized frequency, the spectra of heart rate variability found in our living subjects. Analysis of the power spectra of hydrogen isotope ratios in hair from a patient with neurodegeneration revealed the same spectral features seen in the patient's heart-rate variability. Our study shows that spectral analysis of stable isotope ratios in readily available tissues such as hair could become a powerful diagnostic tool when effective treatments and neuroprotective drugs for neurodegenerative diseases become available. It also suggests that similar analyses of archaeological specimens could give insight into the physiology of ancient people and animals.

  17. Immediate Desensitization in Teeth Affected by Amelogenesis Imperfecta

    OpenAIRE

    Moreira,Rudá França; Figueiredo,Rossana Gomes; Oliveira,Henrique Eduardo de; Fonseca,Ana Christina Lamosa da; Miranda,Mauro Sayão de

    2016-01-01

    Abstract The aim of this paper was to describe a clinical case of immediate dental desensitization using a self-etch adhesive system in an adolescent patient diagnosed with amelogenesis imperfecta (AI). AI was associated with severe tooth sensitivity, treated by the application of a universal adhesive system for desensitization of the teeth affected by AI. Reduction of tooth sensitivity was assessed using a visual analog scale during all reevaluations. The technique was effective for reducing...

  18. Management of intruded primary teeth after traumatic injuries

    OpenAIRE

    Hirata, Ryoko; Kaihara, Yasutaka; Suzuki, Junji; Kozai, Katsuyuki

    2011-01-01

    Intrusions occur frequently in the primary dentition. It has been reported that conservative treatment of the intruded primary tooth is preferred if the apex is away from the permanent tooth germ. Conservative treatments include waiting for spontaneous re-eruption, and surgical re-positioning and fixation. Few papers have been published in Japan comparing the prognoses of intruded primary teeth between these two different modes of treatment. Therefore, optimal treatment for intruded primary t...

  19. Self inflicted human teeth bites: a case report

    OpenAIRE

    Singh, Satinder Pal; Aggarwal, Akashdeep; Kaur, Sumeet; Singh, Dalbir

    2014-01-01

    Human infighting has been a part of our civilization since times immemorial. These incidences may go unnoticed or may attract attention of law enforcing agencies depending upon the severity of the offence. Though weapons are generally employed to inflict injuries, rare cases have been reported in literature where human teeth have been used to serve this purpose. Human bites may be self inflicted or self suffered in connivance with others to level an allegation against an adversary. We are pre...

  20. Association between maxillary sinus pathologies and healthy teeth

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    Gina D. Roque-Torres

    2016-02-01

    Full Text Available ABSTRACT INTRODUCTION: The proximity of the roots to the maxillary sinus can create a variety of risks. OBJECTIVE: To evaluate the relationship between the roots of healthy teeth and the maxillary sinus, as well as the occurrence of sinus pathologies. METHODS: Three radiologists analyzed 109 cone beam computed tomography (CBCT images. The Kappa test was used to assess the intra- and inter-rater agreement. The chi-squared test and prevalence ratio were used to test the hypothesis that roots of healthy teeth in the maxillary sinus favored the occurrence of sinus pathologies ( p = 0.01. RESULTS: Intra- and inter-rater agreement ranged from good to excellent. The chi-squared test demonstrated a statistically significant difference ( p = 0.006 between the tooth roots in diseased maxillary sinuses (6.09% and those in normal sinuses (3.43%. The prevalence ratio test showed a statistically significant higher prevalence of tooth roots in diseased sinuses than in normal sinuses ( p < 0.0001. Roots in the maxillary sinus were 1.82 times more associated with diseased sinuses. CONCLUSION: Dental roots in the maxillary sinus are almost twice as likely to be associated with diseased sinuses than normal sinuses. Healthy teeth whose roots are inside the maxillary sinus may induce an inflammatory response in the sinus membrane. It is suspected that dental procedures may exacerbate the condition.

  1. Effects of centric relation prematurities of the frontal teeth.

    Science.gov (United States)

    Rottner, Kurt; Richter, Ernst-Jürgen; Fanghänel, Jochen; Gedrange, Tomas; Kubein-Meesenburg, Dietmar; Nägerl, Hans; Proff, Peter

    2007-01-01

    Centric relation prematurities of frontal teeth are frequently found with patients who have severe orthodontic anomalies or received extensive restorative treatment. They can cause a range of symptoms ranging from loosening of the teeth to temporomandibular disorders (TMD). The objective of this work has been to derive a mathematical description of the mandibular and periodontal forces generated by anterior prematurities for different incisor relations. In order to quantify the effect of contact area (location and inclination) and the tooth inclination, a two-dimensional mathematical approach was used. Vectorisation of the forces and bending moments makes it possible to predict under which conditions the load increase mainly affecting the anterior teeth can and may cause localized pain and eventually loosening and flaring/crowding of the upper/lower incisors and under which conditions the temporomandibular joint will suffer a large increase in retrusive force, which potentially leads to TMD. For 10 patients with anterior prematurities, analysis of the incisor relation was carried out. For all cases the conclusions drawn from the mathematical model were in full agreement with the reported symptoms, which could be successfully treated.

  2. Fracture resistance of bleached teeth restored with different procedures

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    Matheus Coelho Bandéca

    2012-08-01

    Full Text Available This study evaluated the fracture resistance of teeth submitted to internal bleaching and restored with different non-metallic post. Eighty mandibular incisors were endodontically treated and randomly divided in 10 groups (n = 8: G1- restored with composite resin (CR, G2- CR + fiber-reinforced composite post (FRC, Everstick post, Sticktech cemented with resin cement self-etch adhesive (RCS, Panavia F 2.0, Kuraray, G3- CR + FRC + self-adhesive resin cement (SRC, Breeze, Pentral Clinical, G4- CR+ glass fiber post (GF, Exacto Post, Angelus + RCS, G5- CR + GF + SRC. The G6 to G10 were bleached with hydrogen peroxide (HP and restored with the same restorative procedures used for G1 to G5, respectively. After 7 days storage in artificial saliva, the specimens were submitted to the compressive strength test (N at 0.5 mm/min cross-head speed and the failure pattern was identified as either reparable (failure showed until 2 mm below the cement-enamel junction or irreparable (the failure showed <2 mm or more below the cement-enamel. Data were analyzed by ANOVA and Tukey test (α = 0.05. No significant difference (p < 0.05 was found among G1 to G10. The results suggest that intracoronal bleaching did not significantly weaken the teeth and the failure patterns were predominately reparable for all groups. The non-metallic posts in these teeth did not improve fracture resistance.

  3. Prevalence of Impacted Wisdom Teeth in Middle Black Sea Population

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    Ferhat Ayranci, Melih Mehmet Omezli, Efe Can Sivrikaya,

    2017-08-01

    Full Text Available Objective: The aim of this cross-sectional randomized study was to investigate the prevalence and angulation of third molar impaction in patients between 19‒26 years old who were living in the Middle Black Sea region of Turkey. Methods: Total 1006 patients between 19 and 26 years of age who were referred to the Ordu University Faculty of Dentistry Department of Oral Maxillofacial Surgery between 2010 and 2015 were included in the study. Of these 1,006 patients, 410 were male and 596 were female. The prevalence and positions of the impacted third molar teeth from the 4th quadrant on the panoramic radiographs were documented according to the classifications of Pell and Gregory as well as that of Winter. In the Pell and Gregory classification, the teeth in class C were evaluated as impacted teeth. Results: There was a total of 1,518 impacted molars. Of the included patients, 48.3% had impacted third molars. The most common angulation of impacted third molars was the vertical position in both mandible (28.4% and maxilla (28.8%. The prevalence of impacted mandibular third molars (57.3% was significantly higher than that of the impacted maxillary third molars (42.7% (P0.05. Conclusion: The pattern of third molar impaction in the Middle Black Sea region was characterized by a high prevalence of level C impaction with a vertical position that was greater in the mandibles and had no sex predilection.

  4. Association between maxillary sinus pathologies and healthy teeth.

    Science.gov (United States)

    Roque-Torres, Gina D; Ramirez-Sotelo, Laura Ricardina; Vaz, Sergio Lins de Azevedo; Bóscolo, Solange Maria de Almeida de; Bóscolo, Frab Norberto

    2016-01-01

    The proximity of the roots to the maxillary sinus can create a variety of risks. To evaluate the relationship between the roots of healthy teeth and the maxillary sinus, as well as the occurrence of sinus pathologies. Three radiologists analyzed 109 cone beam computed tomography (CBCT) images. The Kappa test was used to assess the intra- and inter-rater agreement. The chi-squared test and prevalence ratio were used to test the hypothesis that roots of healthy teeth in the maxillary sinus favored the occurrence of sinus pathologies (p=0.01). Intra- and inter-rater agreement ranged from good to excellent. The chi-squared test demonstrated a statistically significant difference (p=0.006) between the tooth roots in diseased maxillary sinuses (6.09%) and those in normal sinuses (3.43%). The prevalence ratio test showed a statistically significant higher prevalence of tooth roots in diseased sinuses than in normal sinuses (pmaxillary sinus were 1.82 times more associated with diseased sinuses. Dental roots in the maxillary sinus are almost twice as likely to be associated with diseased sinuses than normal sinuses. Healthy teeth whose roots are inside the maxillary sinus may induce an inflammatory response in the sinus membrane. It is suspected that dental procedures may exacerbate the condition. Copyright © 2015 Associação Brasileira de Otorrinolaringologia e Cirurgia Cérvico-Facial. Published by Elsevier Editora Ltda. All rights reserved.

  5. Analysis of microleakage of temporary restorative materials in primary teeth

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    Geórgia Linhares dos Santos

    2014-01-01

    Full Text Available Aim: The aim of this study was to compare the coronal microleakage of restorative materials used between sessions of endodontic treatment in primary teeth. Materials and Methods: Forty healthy primary canines were chosen and randomly allocated to four groups: Group 1 - Cimpat Branco ® (n = 10, Group 2 - Bioplic ® (n = 10, Group 3 - Maxxion R ® glass ionomer cement (n = 10, and Group 4 (control - Z350 ® composite resin (n = 10. Class V cavities were created and fillings carried out following the manufacturer′s instructions. The teeth were submitted to thermocycling, sealed, and immersed in 0.5% basic fuchsin solution for 24 h. The teeth were split along their long axis in the vestibulolingual direction and the tooth-restorative material interface was photographed. The percentage of microleakage was calculated using the ImageJ program. Data were analyzed using the analysis of variance (ANOVA F-test and Bonferroni′s t-test, with a 5% level of significance. Results: The following mean percentages of microleakage were found: Group 1 = 16.08%, Group 2 = 46.98%, Group 3 = 47.93%, and Group 4 = 11.03%. Statistically, significant differences were found in the comparison of Groups 1 and 4 to Groups 2 and 3. Conclusion: Cimpat Branco ® had a lower percentage of microleakage in comparison to Bioplic ® and Maxxion R ® glass ionomer cement.

  6. Interactions between visitors and Formosan macaques (Macaca cyclopis) at Shou-Shan Nature Park, Taiwan.

    Science.gov (United States)

    Hsu, Minna J; Kao, Chien-Ching; Agoramoorthy, Govindasamy

    2009-03-01

    Ecotourism involving feeding wildlife has raised public attention and is a controversial issue, especially concerning nonhuman primates. Between July 2002 and April 2005, the behavior of monkeys and tourists was collected through scan samplings, focal samplings and behavior samplings at the Shou-Shan Nature Park located in Taiwan's second largest city--Kaohsiung. In addition, the number of tourists and monkeys was counted in different hours and places within the park. Four hundred visitors were interviewed using a questionnaire to gather data on sex, age, purpose and frequency of visit to the park. The number of tourists was significantly higher during weekends than in weekdays in all locations. Humans dominated in the initiation of interspecies interactions--the overall ratio of human-initiated and monkey-initiated interactions was 2.44:1. Human-monkey conflicts accounted for only 16.4% of the total interactions (n=2,166), and adult human males and adult male macaques participated in higher rates than other age/sex groups in these conflicts. Visitors showed more affiliative behavior (15.9%) than agonistic behavior (8%) toward the macaques. In response to visitors' threat or attack, the Formosan macaques mostly showed submissive behavior with bared teeth, squealed or ran away to avoid confrontation (69.1%)--only few responded with counteraggression (18.7%). This study for the first time provided evidence that food provisioning increased both the frequency and duration of aggression among Formosan macaques (P<0.001). During food provisioning, the average frequency and the duration of agonistic events of macaques were more than 4 times higher compared with those without food provisioning. The average frequency of food provision by tourists was 0.73 times/hr--more than twice the incident that monkeys grabbed the food from tourists (0.34 times/hr). If people refrain from feeding monkeys and destroying the city park's natural vegetation, monkeys can be used to educate

  7. Comparison of Calcium Hydroxide and Bioactive Glass after Direct Pulp Capping in Primary Teeth

    Directory of Open Access Journals (Sweden)

    R. Haghgoo

    2007-12-01

    Full Text Available Objective: Bioactive glass is often used as a filler material for repair of dental bone defects.In different studies osteogenic potential of this material was proved, but its dentinogenesisproperty is in doubt. The purpose of this study was to evaluate the histological pulp responses of Calcium hydroxide and Bioactive glass placed directly on exposed pulp tissues.Materials and Methods: Twenty teeth to be extracted due to orthodontic reasons were selected. These teeth were divided into two groups and treated with direct pulp capping.Calcium hydroxide was used for 10 teeth and Bioactive glass for 10 teeth. After 60 daysthe teeth were extracted and prepared for histological evaluation. Finally the data was analyzed with exact Fisher test.Results: All teeth treated with Calcium hydroxide showed inflammation. Internal resorption was seen in six teeth, abscess in five teeth and dentinal bridge in two teeth. Inflammationwas seen in three Bioactive glass samples and dentinal bridge in seven teeth, but internal resorption and abscess were not seen.Conclusion: Bioactive glass appears to be superior to Calcium hydroxide as a pulp capping agent in primary teeth.

  8. Histological Evaluation and Management of Rare Case of Supernumerary “Ghost” Teeth

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    Dino Re

    2017-01-01

    Full Text Available Supernumerary teeth are teeth that exceed the normal dental formula. Their prevalence in the permanent dentition is 1–14% and they occur more frequently in maxilla with a sex ratio of 2 : 1 in favor of males. They are often associated with syndromes but there are examples of nonsyndromic multiple supernumerary teeth reported in the literature. CBCT is usually the best exam for radiographic diagnosis and treatment planning, because it provides 3D information about location and morphology of supernumerary teeth. This paper reports a rare case of four supernumerary teeth in a nonsyndromic 9-year-old boy. The peculiarity of this case is that two more exceeding teeth were found during surgical procedure. After extraction, all the teeth underwent a histological undecalcified processing for light microscopical examination. The two “ghost” supernumerary teeth seemed to be primordial dental germs, possibly resulting from an altered odontogenic process. After supernumerary teeth extraction, X-rays and exfoliation monitoring are recommended, since permanent retained teeth often erupt naturally or, at least, improve their condition. Radiographic follow-up is also useful in order to assess the formation of further teeth due to the hyperactivity of the dental lamina.

  9. Gender-dependent dimorphic teeth in four species of Mesoamerican plethodontid salamanders (Urodela, Amphibia).

    Science.gov (United States)

    Ehmcke, Jens; Wistuba, Joachim; Clemen, Günter

    2004-06-01

    The tooth shapes of premaxillary and maxillary teeth of adults of four Mesoamerican salamander species (Urodela, Plethodontidae) were examined. Using scanning electron microscopy we determined whether the monocuspid teeth that are present only on the premaxillary of sexually mature males belong to the conical, unbladed, monocuspid tooth type found in urodele larvae or whether they represent morphological variations of the typical, bladed, bicuspid teeth of metamorphosed individuals. The teeth of some studied species are, in fact, unbladed and in some cases show one very reduced tip. But none of the studied teeth is per definitionem monocuspid and no tooth shows an enameloid layer between dentine shaft and enamel cap, which is always present in the teeth of early urodele larvae. The "monocuspid" teeth of adult males of Mesoamerican plethodontid salamanders have to be considered a morphological variation of the metamorphosed, bicuspid tooth type typical for metamorphosed urodeles.

  10. Characterization, diagnosis and ablation of human teeth using blue laser at 457 nm

    Science.gov (United States)

    El-Sherif, Ashraf F.; Gomaa, Walid; El-Sharkawy, Yasser H.

    2014-02-01

    The light interaction with tissue is governed by the specific wavelength of the laser used and the optical properties of target tissue. Absorption, scattering and fluorescence together can probably be used as the basis of quantitative diagnostic methods for teeth caries. The absorption coefficient of human teeth was determined from detached wet teeth (incisors and premolars). Laser absorption of these teeth was measured using compact blue laser source at wavelength of 457 nm and a high resolution spectrometer equipped with an integrating sphere. The average absorption coefficient of abnormal caries tissue of human teeth is observed to be higher than the normal ones. Detection and diagnosis of caries tissues were monitored by high resolution translational scanning of human teeth. We have a powerful tool to diagnosis a caries region of human teeth using blue laser at 457 nm. Ablations of caries region are investigated using higher power of blue laser at 457 nm.

  11. Traumatic displacement of teeth into maxillary sinus cavity: an unusual dentoalveolar fracture.

    Science.gov (United States)

    Gumus, Nazim; Coban, Yusuf Kenan

    2006-11-01

    We present an unusual dentoalveolar fracture case who had displacement of teeth into maxillary sinus cavity. This patient was 15 years old. He had oral bleeding and lost teeth after falling from the top of a building. Examination of maxillofacial region showed that there were left maxillary teeth lost, alveolar fracture, gingival bleeding and laserations. Maxillofacial bones were found intact. Canine, both premolars and the first molar teeth on left maxilla were lost. Pantomographic evaluation viewed two teeth in the left maxillary sinus. In addition, computerized tomography clearly showed oroantral fistula, alveolar fracture and teeth into maxillary sinus. Extraction of teeth from sinus cavity was performed as well as repair of oroantral fistula and alveolar fracture. This patient is thought that dentoalveolar injury may be more serious than expected according to the oral examination and it requires careful evaluation, even if dentoalveolar trauma does not pose a significant morbid risk.

  12. 太行山猕猴掌面肤纹三角分布%Distribution of the triradius on the palms in Taihang Macaca mulatta

    Institute of Scientific and Technical Information of China (English)

    赵晓进; 范红军; 靳想

    2012-01-01

    Objective:To report the characteristic of the triradius on the palms in the Taihang Macaca mulatto.. Methods: The sample comprised 31 individuals (8 males and 23 females) whose dermatoglyphics were completed and clear. The triradii on palms were taken with a digital camera or direct observation. Results : There constantly existed ten triradii on the palms in Macaca mulatto , and the average number of the triradius was 9. 1, and they ranged from 8 to 11. Conclusion: There is a significant difference in the position of palmar triradii between Macaca mulatto and other primates. Sex difference and bi-manual difference were not significant. The difference is mainly due to the evolution degree of primates, the development of palmar pad, the dermatoglyphic patterns and the printing procedure.%目的:了解太行山猕猴掌面三角的分布特征.方法:直接观察太行山猕猴掌面肤纹标本31例.结果:太行山猕猴掌面三角常出现的三角有10个,三角数目在8~11个之间,平均9.1个.结论:太行山猕猴掌面三角分布模式与其他灵长类掌面三角相比有差异.掌面三角性差和侧差无差异.造成这些差异的主要原因与灵长类动物进化程度、掌垫发育、花纹类型以及观察方法有关.

  13. [Effects of Er, Cr: YSGG laser on the root surface of periodontitis and healthy teeth].

    Science.gov (United States)

    Qu, Chun-na; Kang, Jun; Luan, Qing-xian

    2016-02-18

    To evaluate the effects of Er, Cr: YSGG laser on the root surface of periodontally involved teeth and healthy teeth, concerning the microstructure and the roughness. Eight freshly extracted teeth due to severe periodontitis and eight freshly extracted teeth due to orthodontic reasons or being third molar were chosen in this study. The root surface of each tooth was divided into four areas, and received four treatment no treatment (control group); root planing with Gracey scaler for 30 seconds; irradiation by the lower power Er, Cr: YSGG laser; irradiation by the higher power Er, Cr: YSGG laser. Four periodontally involved teeth and four healthy teeth were used for the evaluation of microstructure using scanning electron microscope (SEM). The other four periodontitis teeth and four healthy teeth were used for the evaluation of roughness (Ra value) using 3D profiler. Smear layer was found on the teeth scaled by Gracey scaler, while the teeth irradiated by Er, Cr: YSGG laser demonstrated a melting surface with less smear layer. In the periodontitis teeth irradiated by the higher power, opening dentinal tubules could be observed. For the periodontally involved teeth, the Ra values of groups 1 to 4 were (237.4 ± 20.0) nm, (135.7 ± 11.9) nm (P=0.01), (463.6 ± 49.3) nm (Plaser can affect the microstructure of the cementum of the periodontitis teeth and healthy teeth. Irradiation by the Er, Cr: YSGG laser resulted in a melting surface with less smear layer and increased the roughness in the surface of root.

  14. Teeth number anomalies in permanent dentition among non-syndromic dental patients.

    Science.gov (United States)

    Aslan, Belma Işik; Akarslan, Zühre Zafersoy

    2013-03-01

    The aim of this study was to establish teeth number anomalies in relation to gender, tooth type, location, distribution pattern and the association between frequently missing teeth among a group of dental patients in Turkey. A total of 378 non-syndromic patients (240 females and 138 males) with an age range of 7-45 (x +/- SD = 22.07 +/- 3.6) having evidence of absent or excess teeth were evaluated in the study. Pearson Chi-square, Fisher's exact, McNemar and Kappa coefficients were used for statistical analysis. 237 patients had a total of 546 congenitally missing teeth and 141 had 185 excess teeth. Congenitally missing teeth were more commonly seen rather than the presence of supernumerary teeth. Difference was determined in the frequent locations of congenital missing and supernumerary teeth. The most frequent missing tooth type was found to be the mandibular second premolar (26.6%), while the majority of supernumerary teeth were located in the anterior region of the maxillary arch (37.9%). Both teeth number anomalies were more commonly seen among females. In hypodontia cases the occurrence of symmetrical agenesis of laterals and second premolars in maxilla; centrals and second premolars in mandible was notable. Agenesis of mandibular centrals was found to be associated with maxillary lateral agenesis in males. Also higher prevalence of molar teeth agenesis was determined in the occurrence of at least 4 teeth agenesis. These findings will serve as information about the contemporary demographic pattern of teeth number anomalies among non-syndromic Turkish dental patients and can provide evidence that agenesis of some teeth symmetrically or together are the products of the same genetic mechanisms.

  15. Comparison of mineral trioxide aggregate and formocresol as pulp-capping agents in pulpotomized primary teeth.

    Science.gov (United States)

    Agamy, Hadeer A; Bakry, Niveen S; Mounir, Maha M F; Avery, David R

    2004-01-01

    The aim of this study was to use clinical, radiographic, and histologic examinations to compare the relative success of gray mineral trioxide aggregate (MTA), white MTA, and formocresol as pulp dressings in pulpotomized primary teeth. Twenty-four children, each with at least 3 primary molars requiring pulpotomy, were selected for this study's clinical and radiographic portion. An additional 15 carious primary teeth planned for serial extraction were selected for this study's histologic portion. All selected teeth were evenly divided into 3 test groups and treated with pulpotomies. Gray MTA was used as the pulp dressing for one third of the teeth, white MTA was the dressing for one third, and the remaining one third were treated with formocresol. The treated teeth selected for the clinical and radiographic evaluations were monitored periodically for 12 months. The treated teeth selected for histologic study were monitored periodically and extracted 6 months postoperatively. Four children with 12 pulpotomized teeth failed to return for any follow-up evaluations in the clinical and radiographic study. Of the remaining 60 teeth in 20 patients, 1 tooth (gray MTA) exfoliated normally and 6 teeth (4 white MTA and 2 formocresol) failed due to abscesses. The remaining 53 teeth appeared to be clinically and radiographically successful 12 months postoperatively. Pulp canal obliteration was a radiographic finding in 11 teeth treated with gray MTA and 1 tooth treated with white MTA. In the histologic study, both types of MTA successfully induced thick dentin bridge formation at the amputation sites, while formocresol induced thin, poorly calcified dentin. Teeth treated with gray MTA demonstrated pulp architecture nearest to normal pulp by preserving the odontoblastic layer and delicate fibrocellular matrix, yet few inflammatory cells or isolated calcified bodies were seen. Teeth treated with white MTA showed a denser fibrotic pattern, with more isolated calcifications in the

  16. 猕猴脱毛的营养学因素分析%Analysis on the Nutriology Parameters of Shed in Macaca mulatta

    Institute of Scientific and Technical Information of China (English)

    鲁帅尧; 和占龙; 陈丽雄; 赵远; 禹文海; 王俊斌; 杨凤梅

    2011-01-01

    Objective To improve and prevent shed of Macaca mulatta by comparison and analysis the nutriology parameters. Methods Macaca mulatta was divided into A, B and C group according to condition of their hair. Hair and serum were collected to determine trace elements, amino acid and mineral in serum. Results The content of Mn, Zn, Pb and As in hair show extremely significant difference (P <0. 01 ), but no significant change in the content of Cu and Fe (P >0. 05). The content of Pro, Val, NH3, Arg, Tyr, Gystine, Phe, Lys, His and total amino acids in hair show extremely significant difference (P <0. 01 ). The content of trace element in serum was no big change, except Mg, P, Cu and Ca in A and B groups were higher than C group. Conclusion The quantity of Mn and Zn in addition maybe the reason caused Macaca mulatta shed. Gystine may improve and enhance the hair quantity; Ca, Mg, P and Cu possibly can affect the hair quantity in artificial raising Macaca mulatta when fed in high nutritional level.%目的 通过对猕猴脱毛的相关营养学指标的比较分析,为改善人工饲养猕猴脱毛状况及其防治提供参考数据.方法 根据被毛状况分组A、B、C,采集试验猴被毛和血清,测定其微量元素和氨基酸以及血清矿物元素,对各组相应指标进行比较分析.结果 各组试验猴被毛Cu、Fe含量无显著性差异(P>0.05),但Mn、Zn、Pb、As则均有极显著性差异(P0.05).A、B组的血清Mg、P、Cu和Ca的含量高于C组,其余矿物元素的含量基本一致.结论 Mn过量、Zn的供给不足可能是影响人工饲养猕猴被毛质量的因素;胱氨酸对改善猕猴被毛品质、提高被毛质量应该有一定作用;高营养水平的Ca、Mg、P和Cu可能会影响人工饲养的猕猴的被毛质量.

  17. 改良腭弓矫治后牙锁节对后牙功能恢复的影响%Influence of promote palatine arch treating buccal teeth lock on occlusion function recovery of buccal teeth

    Institute of Scientific and Technical Information of China (English)

    马宁; 孙应明; 白槐延

    2002-01-01

    @@ Background: Buccal teeth occlusion lock is a kind of common malocclusion malformation in orthodonic clinic. Traditional treatment to buccal teeth occlusion lock is interactive traction of upper and lower buccal teeth.This treatment had shortcoming such as insufficient anchorage and elongation of buccal teeth.We adopted promote fix palatine arch therapy, which recovery patients' occlusion function by clinical observation.

  18. Dentists make larger holes in teeth than they need to if the teeth present a visual illusion of size.

    Directory of Open Access Journals (Sweden)

    Robert P O'Shea

    Full Text Available BACKGROUND: Health care depends, in part, on the ability of a practitioner to see signs of disease and to see how to treat it. Visual illusions, therefore, could affect health care. Yet there is very little prospective evidence that illusions can influence treatment. We sought such evidence. METHODS AND RESULTS: We simulated treatment using dentistry as a model system. We supplied eight, practicing, specialist dentists, endodontists, with at least 21 isolated teeth each, randomly sampled from a much larger sample of teeth they were likely to encounter. Teeth contained holes and we asked the endodontists to cut cavities in preparation for filling. Each tooth presented a more or less potent version of a visual illusion of size, the Delboeuf illusion, that made the holes appear smaller than they were. Endodontists and the persons measuring the cavities were blind to the parameters of the illusion. We found that the size of cavity endodontists made was linearly related to the potency of the Delboeuf illusion (p<.01 with an effect size (Cohen's d of 1.41. When the illusion made the holes appear smaller, the endodontists made cavities larger than needed. CONCLUSIONS: The visual context in which treatment takes place can influence the treatment. Undesirable effects of visual illusions could be counteracted by a health practitioner's being aware of them and by using measurement.

  19. Evaluation of the Dentistry course of UNIVILLE students’ knowledge about the use of the extracted teeth in the graduation and the teeth bank

    Directory of Open Access Journals (Sweden)

    Débora ZUCCO

    2006-05-01

    Full Text Available The aim of this study was, through a questionnaire, evaluate the levelof knowledge of the students from graduation in Dentistry course –UNIVILLE –, about the teeth bank: its activities and functioning,biosecutity in teeth manipulation and, especially, to find out the reason why the students do not donate spontaneously extracted teeth to the bank.A questionnaire was elaborated and applied to the studentsfrom the first to the fifth year of graduation with pertinent questions about the teeth bank, such as the use of teeth in the disciplines of the course, biosecurity and donation of dental elements. After the questionnaire was applied, it was possible to evidence that: all the interviewed students (100% had needed extracted dental elements to use in laboratory assignments; 84,2% have reported difficulty in the obtainment of the requested teeth; about biosecurity, 66.6% of the students have stated that they had already manipulated extracted teeth without individual protection equipment; even knowing that the pulp and periodontal tissues can present sanguineous pathogenic microorganisms transmissible to the human being (86,8%. It was evidenced that the main reason why students did not participate effectively in the donation of “private supplies”, is the unfamiliarity with the activities of the teeth bank, its norms of procedure, protocols of donation and, mainly, the withdrawal of dental elements.

  20. Clinical longevity of ceramic laminate veneers bonded to teeth with and without existing composite restorations up to 40 months

    NARCIS (Netherlands)

    Gresnigt, Marco M. M.; Kalk, Warner; Ozcan, Mutlu

    2013-01-01

    This study evaluated the survival rate of ceramic laminate veneers bonded to teeth with and without existing composite restorations (ECR). Twenty patients (mean age: 49.7 years) received 92 feldspathic ceramic laminate veneers (Shofu Vintage AL) on the maxillary teeth (intact teeth: n = 26; teeth wi

  1. Comparison of fracture resistance of teeth restored with ceramic inlay and resin composite: An in vitro study

    Directory of Open Access Journals (Sweden)

    Priti D Desai

    2011-01-01

    Conclusion: The fracture resistant strength of teeth restored with ceramic inlay was comparable to that of the normal intact teeth or slightly higher, while teeth restored with direct composite resin restoration showed less fracture resistant strength than that of the normal teeth.

  2. Jaw-muscle architecture and mandibular morphology influence relative maximum jaw gapes in the sexually dimorphic Macaca fascicularis.

    Science.gov (United States)

    Terhune, Claire E; Hylander, William L; Vinyard, Christopher J; Taylor, Andrea B

    2015-05-01

    Maximum jaw gape is a performance variable related to feeding and non-feeding oral behaviors, such as canine gape displays, and is influenced by several factors including jaw-muscle fiber architecture, muscle position on the skull, and jaw morphology. Maximum gape, jaw length, and canine height are strongly correlated across catarrhine primates, but relationships between gape and other aspects of masticatory apparatus morphology are less clear. We examine the effects of jaw-adductor fiber architecture, jaw-muscle leverage, and jaw form on gape in an intraspecific sample of sexually dimorphic crab-eating macaques (Macaca fascicularis). As M. fascicularis males have relatively larger maximum gapes than females, we predict that males will have muscle and jaw morphologies that facilitate large gape, but these morphologies may come at some expense to bite force. Male crab-eating macaques have relatively longer jaw-muscle fibers, masseters with decreased leverage, and temporomandibular joint morphologies that facilitate the production of wide gapes. Because relative canine height is correlated with maximum gape in catarrhines, and males have relatively longer canines than females, these results support the hypothesis that male M. fascicularis have experienced selection to increase maximum gape. The sexes do not differ in relative masseter physiologic cross-sectional area (PCSA), but males compensate for a potential trade-off between muscle excursion versus muscle force with increased temporalis weight and PCSA. This musculoskeletal configuration is likely functionally significant for behaviors involving aggressive canine biting and displays in male M. fascicularis and provides additional evidence supporting the multifactorial nature of the catarrhine masticatory apparatus. Our results have implications for the evolution of craniofacial morphology in catarrhine primates and reinforce the importance of evaluating additional factors other than feeding behavior and diet

  3. Early involvement in friendships predicts later plasma concentrations of oxytocin and vasopressin in juvenile rhesus macaques (Macaca mulatta

    Directory of Open Access Journals (Sweden)

    Tamara Aliza Rachel Weinstein

    2014-08-01

    Full Text Available The neuropeptides oxytocin (OT and vasopressin (AVP are involved in social bonding in attachment relationships, but their role in friendship is poorly understood. We investigated whether rhesus macaques’ (Macaca mulatta friendships at age one predicted plasma OT and AVP at two later time points. Subjects were 54 rhesus macaques at the California National Primate Research Center. Blood was drawn during a brief capture-and-release in the home cage, and plasma assayed for OT and AVP using an enzyme immunoassay. Separate linear mixed models for each sex tested the effects of dominance rank, age, sampling time point, housing condition, parturition status, two blood draw timing measures, and five friendship types: proximity friendships, play friendships, reciprocal friendships (a preference for a peer that also preferred the subject, multiplex friendships (friendships displayed in more than one behavioral domain, and total number of friendships. Females’ number of reciprocal and play friendships at age one significantly predicted later OT; additionally, these two friendship types interacted with rank, such that high-ranking females with the fewest friendships had the highest OT concentrations. Friendship did not predict later OT levels in males, however proximity, play, reciprocal, and total number of friendships predicted males’ plasma AVP. Play and total number of friendships also tended to predict AVP in females. Our results show that peripheral measures of neuroendocrine functioning in juvenile rhesus monkeys are influenced by early involvement in friendships. Friendships have an especially strong impact on an individual’s psychosocial development, and our data suggest OT and AVP as potential underlying mechanisms. Moreover, sex differences in the functioning of the OT and AVP systems, and their relation to friendship, may have important clinical implications for the use of OT as a therapeutic, as well as informing the social context in

  4. The trade balance of grooming and its coordination of reciprocation and tolerance in Indonesian long-tailed macaques (Macaca fascicularis).

    Science.gov (United States)

    Gumert, Michael D; Ho, Moon-Ho R

    2008-07-01

    We collected data on grooming, proximity, and aggression in long-tailed macaques (Macaca fascicularis) in Kalimantan, Indonesia. We used this data to study how grooming influenced a receiver's (B) behavior towards the bout's initiator (A). In our first analysis, post-grooming samples were collected after A groomed B. These were compared to matched-control samples of similar conditions but A had not previously groomed B. This comparison was performed on 26 individuals (16 female, 3 male, 7 immature) and tested whether A's initial act of grooming increased the pair's time in proximity and the amount of time B groomed A. We also tested if A's grooming decreased B's aggression towards A per time in proximity. Rates of B-->A aggression per time in proximity with A for 39 individuals (18 female, 5 male, 16 immature) were compared between post-grooming and focal sample data. Finally, we studied 248 grooming bouts to test if the first two grooming episodes were time matched. We assessed the influence of age, sex, rank and inferred kinship on time matching, and controlled for individual variation and tendency to groom using a general linear mixed model. Our results showed that A-->B grooming acted to increase B-->A grooming and the pair's proximity, while lowering B-->A aggression. Despite these effects, episodes in grooming bouts were generally not matched, except weakly among similar partners (i.e., female pairs and immature pairs). Grooming imbalance was greatest across age-sex class (i.e., male-female and adult-immature pairs). In similar pairs, grooming duration was skewed in favor of high-ranking individuals. We conclude grooming established tolerance and increased the likelihood that grooming reciprocation would occur, but grooming durations were not typically matched within bouts. Lack of time matching may be the result of grooming that is performed to coordinate interchanges of other social services.

  5. High-fat diet combined with low-dose streptozotocin injections induces metabolic syndrome in Macaca mulatta.

    Science.gov (United States)

    Li, Linzhao; Liao, Guangneng; Yang, Guang; Lu, Yanrong; Du, Xiaojiong; Liu, Jingping; Li, Lan; Wang, Chengshi; Li, Li; Ren, Yan; Zhong, Zhihui; Cheng, Jingqiu; Chen, Younan

    2015-08-01

    Metabolic syndrome (MetS) is associated with abdominal obesity, hyperlipidemia, insulin resistance, and type 2 diabetes mellitus, and increases the risk of cardiovascular disease. Given the complex multifactorial pathogenesis of MetS, qualified animal models are currently seriously limited for researchers. The aim of our study was to develop a MetS model in juvenile rhesus monkeys (Macaca mulatta). Rhesus monkeys (1-year-old) fed a high-fat diet (15 % fat, 2 % cholesterol) were used as the HF group (n = 6), and those on a normal diet (5 % fat) were used as the control group (n = 4). After being fed a high-fat diet for approximately 12 months, 2 monkeys (HF + STZ group) were injected with low-dose streptozotocin (STZ, 25 mg/kg) twice, with a 7 days interval, and were then fed the same diet continuously for another 24 months. After 36 months of treatment, the high-fat diet monkeys, including the HF and HF + STZ groups, had acquired increased body weights, abnormal serum lipids, and impaired glucose tolerance compared to the control group. In addition, much more marked metabolic changes were observed in the two monkeys of the HF + STZ group, particularly in terms of high-blood glucose level and insulin resistance. Morphological observation of biopsies of liver and pancreatic tissues showed decreased islet number and mass and decreased insulin staining in the monkeys of the HF + STZ group. In addition, Oil red O staining suggested remarkable accumulation of lipid droplets in the hepatocytes. Our study suggested that a long-term high-fat diet followed with a low-dose STZ was able to induce MetS in juvenile rhesus monkeys with faster pathophysiological progress compared with high-fat diet induction alone. Our primary data showed that this method may have potentials to develop MetS animal model in non-human primates.

  6. Response of Rhesus Macaques (Macaca mulatta) to the Body of a Group Member That Died from a Fatal Attack

    Science.gov (United States)

    Buhl, Jacqueline S.; Aure, Bonn; Ruiz-Lambides, Angelina; Gonzalez-Martinez, Janis; Platt, Michael L.; Brent, Lauren J. N.

    2013-01-01

    Among animals that form social bonds, the death of a conspecific may be a significant social event, representing the loss of an ally and resulting in disruptions to the dominance hierarchy. Despite this potential biological importance, we have only limited knowledge of animals' reactions to the death of a group member. This is particularly true of responses to dead adults, as most reports describe the responses of mothers to dead infants. Here, we describe in detail and provide video evidence of the behavioral responses of a group of free-ranging rhesus macaques (Macaca mulatta) immediately after the death of a mid-ranking adult male as a result of a fatal attack. High-ranking male members of the group, suspected to have carried out the attack, dragged and bit the dead body, exhibiting a rate of aggression 20 times greater than baseline levels. Lower-ranking individuals approached and inspected the body by looking closely, smelling, and grooming the fur. There was inconclusive evidence that these rhesus macaques found the death of a conspecific stressful: Levels of grooming between group members after the fatal attack were significantly higher than baseline levels, and higher than levels of grooming after nonfatal attacks. However, when grooming levels were adjusted based on the assumption that individuals positioned close to the body, i.e., those visible to researchers, were more likely to be engaged in grooming than those positioned farther away, this difference from baseline was no longer significant. The rate of self-directed behaviors after the fatal attack was also not different from baseline. Many of the behaviors we observed directed toward the body (aggression, inspection) have been previously reported in chimpanzees and geladas, and are similar to reactions sometimes displayed by humans. As such, this report represents a potentially valuable contribution the nascent field of nonhuman primate thanatology. PMID:23459587

  7. Experimental hepatitis A virus (HAV) infection in cynomolgus monkeys (Macaca fascicularis): evidence of active extrahepatic site of HAV replication.

    Science.gov (United States)

    Amado, Luciane A; Marchevsky, Renato S; de Paula, Vanessa S; Hooper, Cleber; Freire, Marcos da S; Gaspar, Ana Maria C; Pinto, Marcelo A

    2010-02-01

    This work studied the replication sites of hepatitis A virus (HAV) in cynomolgus monkeys (Macaca fascicularis) after intravenous inoculation. The cynomolgus monkeys were inoculated with the Brazilian hepatitis A virus strain (HAF-203). Monkeys were euthanized on days 15, 30, 45 and 60 postinoculation (pi). Liver samples, submandibular salivary gland, mesenteric lymph node and tonsils were removed for virological and pathological evaluation. Immunofluorescence analyses on liver and salivary gland sections using confocal laser scanning microscopy revealed the presence of HAV antigen (HAV Ag). The presence of HAV genome was monitored by real-time PCR. The HAV RNA was detected at 7 days postinoculation (dpi), concomitantly in serum, saliva and faeces. The highest HAV viral load was observed in faeces at 15 dpi (10(5) copies/ml), followed by serum viral load of 10(4) copies/ml at 20 dpi and saliva viral load of 10(3 )copies/ml at 7 dpi. The animals showed first histological and biochemical signs of hepatitis at 15 dpi. The HAV antigen (Ag) was present from day 7 until day 60 pi in the liver and salivary glands. The HAV replicative intermediate was also detected in the liver (4.5 x 10(4) copies/mg), salivary glands (1.9 x 10(3) copies/mg), tonsils (4.2 x 10(1) copies/mg) and lymph nodes (3.4 x 10(1) copies/mg). Our data demonstrated that the salivary gland as an extrahepatic site of early HAV replication could create a potential risk of saliva transmitted infection. In addition, the cynomolgus monkey was confirmed as a suitable model to study the pathogenesis of HAV human infection.

  8. Endozoochorous seed dispersal by Japanese macaques (Macaca fuscata): Effects of temporal variation in ranging and seed characteristics on seed shadows.

    Science.gov (United States)

    Tsuji, Yamato; Morimoto, Mayumi

    2016-02-01

    Variation in seed shadows generated by frugivores is caused by daily, seasonal, and inter-annual variation in ranging, as well as inter-specific variability in gut passage times according to seed characteristics. We studied the extent to which seed weight, specific gravity, and daily (morning, afternoon, and evening) and inter-annual (2004 vs. 2005) variation in ranging affected seed shadows generated by wild Japanese macaques (Macaca fuscata) in northern Japan. The macaques ingested fleshy fruits of 11 species during the two year study period; Viburnum dilatatum (Caprifoliaceae: heavier seeds with higher specific gravity) and Rosa multiflora (Rosaceae: lighter seeds with lower specific gravity) were eaten frequently in both years. The travel distances of macaques after feeding on V. dilatatum and R. multiflora fruits were estimated by combining feeding locations and ranging patterns measured in the field with gut passage times of model seeds in captive animals. Median travel distances after fruit feeding were 431 (quantile range: 277-654) and 478 m (265-646), respectively, with a maximum of 1,261 m. Neither year nor time of day affected travel distances. The gut passage time of model V. dilatatum seeds was longer than that of model R. multiflora seed, but this did not affect dispersal distances. Seed shadows for both species over 2 years showed unimodal distribution (peak: 101-500 m) and more than 90%, 20%, and 3% of ingested seeds were estimated to be dispersed >100, >500, and >1000 m, respectively, the longest known distances among macaque species. R. multiflora seeds tended to be dispersed further in 2004 than 2005, but V. dilatatum seeds were not, implying that inter-annual variations in ranging pattern due to the distribution and abundance of nut fruiting could affect dispersal distance.

  9. The acquisition of Streptococcus mutans by infant monkeys (Macaca fascicularis) and its relationship to the initiation of dental caries.

    Science.gov (United States)

    Beighton, D; Hayday, H; Walker, J

    1982-08-01

    The acquisition and transmission of Streptococcus mutans by 16 consecutively born infant monkeys (Macaca fascicularis) was studied. The 16 infant monkeys were weaned in four groups and caged together to form a commune. Transmission from mother to infant occurred infrequently. Streptococcus mutans was isolated from nine of the mothers but only from the dental plaque of two infant monkeys at weaning at which time the predominant streptococci were S. sanguis and S. mitior. One further animal was colonized by S. mutants during the formation of the commune, but only after it was caged with an infant harbouring the same organism. For 46 d after the completion of the commune, the monkeys were fed a starch-based diet during which time S. mutans of serotypes c, e or h were isolated from the faeces of all 16 animals and from the dental plaque taken from the developmental groove of the first deciduous molar of 11 animals. Faecal transmission appeared to be an important factor in the spread of S. mutans between monkeys in the commune. The monkeys were then fed a caries-promoting high sucrose diet resulting in a rapid increase in the proportion of S. mutans in the plaque and in the faeces. Streptococcus mutans serotype e was more frequently isolated from both plaque and faeces and its predominance may in part be due to the production of a bacteriocin active in vitro against S. mutans serotype h and other species of oral streptococci isolated from monkey dental plaque. The proportion of S. mutans in the developmental groove 8 d after the introduction of the high sucrose diet was significantly related to both the caries status of the groove and the total caries score 6 months later. The results suggest that, in this model of human dental caries, S. mutans is the major bacterial factor in the initiation of tooth decay.

  10. Cloning and high level expression of the biologically active extracellular domain of Macaca mulatta CD40 in Pichia pastoris.

    Science.gov (United States)

    Zhu, Shengyun; Wan, Lin; Yang, Hao; Cheng, Jingqiu; Lu, Xiaofeng

    2016-03-01

    The CD40-mediated immune response contributes to a wide variety of chronic inflammatory diseases. CD40 antagonists have potential as novel therapies for immune disorders. However, the CD40 pathway has not been well characterized in the rhesus monkey Macaca mulatta, which is a valuable animal model for human immune disease. An 834 bp transcript was cloned from peripheral blood mononuclear cells (PBMCs) of rhesus monkey using specific primers designed according to the predicted sequence of M. mulatta CD40 (mmCD40) in GenBank. Sequence analysis demonstrated that mmCD40 is highly homologous to human CD40 (hCD40), with an amino acid sequence identity of 94%. Genes encoding the extracellular domain of mmCD40 and the Fc fragment of the hIgG1 were inserted into a pPIC9K plasmid to produce mmCD40Ig by Pichia pastoris. Approximately 15-20 mg of the mmCD40Ig protein with ∼90% purity could be recovered from 1 L of culture. The purified mmCD40Ig protein can form dimers and can specifically bind CD40L-positive cells. Additionally, the mmCD40Ig protein can bind hCD40L protein in phosphate buffered saline and form a stable combination in a size-exclusion chromatography assay using a Superdex 200 column. Moreover, mmCD40Ig is as efficient as M. mulatta CTLA4Ig (mmCTLA4Ig) to suppress Con A-stimulated lymphocyte proliferation. Additionally, mmCD40Ig only showed mild immunosuppressive activity in a one-way mixed lymphocyte reaction (MLR) system. These results suggest that mmCD40Ig secreted by P. pastoris was productive and functional, and it could be used as a tool for pathogenesis and therapies for chronic inflammatory diseases in a M. mulatta model.

  11. Comparison of Indoor Air Quality between 2 Ventilation Strategies in a Facility Housing Rhesus Macaques (Macaca mulatta).

    Science.gov (United States)

    Monts de Oca, Nicole A; Laughlin, Mitzi; Jenkins, John; Lockworth, Cynthia R; Bolton, Iris D; Brammer, David W

    2015-09-01

    Adequate indoor-air quality (IAQ)--defined by the temperature, relative humidity, and the levels of carbon dioxide, small particles, and total volatile organic compounds (TVOC)--is crucial in laboratory animal facilities. The ventilation standards for controlling these parameters are not well defined. This study assessed the effect of 2 ventilation strategies on IAQ in 2 rooms housing rhesus macaques (Macaca mulatta). We hypothesized that using a demand-controlled ventilation (DCV) system with a baseline ventilation rate of less than 3 fresh-air changes per hour (ACH) would maintain IAQ comparable to or better than the traditional constant flow rate (CFR) system at 12 fresh ACH. During a 60-d study period, each of the 2 rooms operated 30 d on DCV and 30 d on CFR ventilation. In both rooms, temperatures remained more consistently within the established setpoint during the DCV phase than during the CFR phase. Relative humidity did not differ significantly between rooms or strategies. CO₂ was lower during the CFR phase than DCV phase. Small-particle and TVOC levels were lower during CFR in the larger (3060 ft(3)) room but not the smaller (2340 ft(3)) room. During the DCV phase, the larger room was at the baseline airflow rate over 99% of the time and the smaller room over 96% of the time. The DCV strategy resulted in a baseline airflow rate of less than 3 ACH, which in turn provided acceptable IAQ over 96% of the time; higher ventilation rates were warranted only during sanitation periods.

  12. DINAMIKA PROFIL HEMATOLOGI DAN RASIO NETROFIL:LIMFOSIT MONYET EKOR PANJANG (MACACA FASCICULARIS PADA PENGATURAN MIKROKLIMAT RUANGAN

    Directory of Open Access Journals (Sweden)

    Ridzki M.F. Binol

    2010-08-01

    Full Text Available The aim of this study was to obtain the profile of physiological hematology (erythrocyte, PCV, Hb, MCV, MCH, MCHC, and leukocyte and the profile of ratio between neutrophil and lymphocyte of long-tailed macaque (Macaca fascicularis in different microclimate conditions due to the room’s temperature and humidity setting. The symptom of stress was also observed in this study. The research used 10 male macaques aged of 4 until 5 years old which placed in room temperature and humidity of 29,00±1,95°C and 79,52±1,57% respectively 7 days for adaptation period. Further more, the room temperature and humidity were set into 25,79±1,16°C and 80,19±9,05% during 14 days for treatment period. For the last treatment, macaques were reconditioned in room temperature and humidity of 29,00±1,95°C and 79,52±1,57% during 14 days for post-treatment period. Blood samplings were collected through femoralis vein on last day of adaptation period, continued with treatment and post-treatment periods as the day 1, 4, 7, 14, and 28. The results showed that there were not significant difference by room temperature and humidity setting to hematology and neutrophil:lymphocyte ratio. It could be proven by all parameters score obtained were still in normal ranges compared to literatures. There was also no stress symptom based on neutrophil:lymphocyte ratio measurement. Condition with room temperature and humidity of 25,79±1,16°C dan 80,19±9,05% regarded as the most suitable condition for long-tailed macaque’s life

  13. A comparative of G-banded chromosome of Assam Macaque (Macaca assamensis and relationship to human (Homo sapiens

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    Bunjongrat, R.

    2006-05-01

    Full Text Available This research was the first to report a comparative analysis of G-banded chromosome of Assam macaque, Macaca assamensis (Primate, Cercopithecidae and relationship to human, Homo sapiens (Primate, Hominidae. Blood samples were taken from two males and two females held captive in Nakhonratchasima Zoo and Songkla Zoo. After the standard whole blood lymphocyte culture at 37ºC for 72 hr in presence of colchicine, metaphase spreads were performed on microscopic slides and air-dried. G-banding technique was applied to stain the chromosomes. The results showed that the number of diploid chromosomes of Assam macaque was 2n = 42. The type of autosomes are 18 metacentric and 22 submetacentric chromosomes. In addition, a pair of short arm chromosome 13 showed clearly observable satellite chromosome. X-chromosome was the submetacentric and Y chromosome was the smallest telocentric chromosome. We found that chromosome 5, 12, 13, 19 and X had the same G-banding patterns as those of human chromosomes. The short arm of chromosome 13 is similar to the chromosome 22 of human as indicated by G-banding techniques. In addition, the long arm of chromosome 13 is similar to the chromosome 15 of human. These results indicate that the chromosome 13 of the Assam macaque was split into 2 chromosomes. Chromosome 1, 3, 6, 7, 8, 9, 10, 11, 14, 17 and 20 are similar to those of human chromosomes. This study suggest that the chromosome 1 is a pericentric inversion of human chromosome 1. Chromosomes 2, 4, 15, 16, 18 and Y are different from those of human chromosomes. These results show the evolutionary relationship between the Assam macaque and human.

  14. Bovine spongiform encephalopathy infection alters endogenous retrovirus expression in distinct brain regions of cynomolgus macaques (Macaca fascicularis

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    Montag Judith

    2011-06-01

    Full Text Available Abstract Background Prion diseases such as bovine spongiform encephalopathies (BSE are transmissible neurodegenerative diseases which are presumably caused by an infectious conformational isoform of the cellular prion protein. Previous work has provided evidence that in murine prion disease the endogenous retrovirus (ERV expression is altered in the brain. To determine if prion-induced changes in ERV expression are a general phenomenon we used a non-human primate model for prion disease. Results Cynomolgus macaques (Macaca fasicularis were infected intracerebrally with BSE-positive brain stem material from cattle and allowed to develop prion disease. Brain tissue from the basis pontis and vermis cerebelli of the six animals and the same regions from four healthy controls were subjected to ERV expression profiling using a retrovirus-specific microarray and quantitative real-time PCR. We could show that Class I gammaretroviruses HERV-E4-1, ERV-9, and MacERV-4 increase expression in BSE-infected macaques. In a second approach, we analysed ERV-K-(HML-2 RNA and protein expression in extracts from the same cynomolgus macaques. Here we found a significant downregulation of both, the macaque ERV-K-(HML-2 Gag protein and RNA in the frontal/parietal cortex of BSE-infected macaques. Conclusions We provide evidence that dysregulation of ERVs in response to BSE-infection can be detected on both, the RNA and the protein level. To our knowledge, this is the first report on the differential expression of ERV-derived structural proteins in prion disorders. Our findings suggest that endogenous retroviruses may induce or exacerbate the pathological consequences of prion-associated neurodegeneration.

  15. Ordered recall in rhesus macaques (Macaca mulatta: Can monkeys recall the correct order of sequentially presented images?

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    Heather E O'Neil

    2006-01-01

    Full Text Available Previous research has demonstrated that rhesus monkeys (Macaca mulatta are capable of identifying sequentially shown images in any order among distractors (i.e. images not part of the list sequence. We investigated ordered recall in rhesus monkeys in which subjects were expected to recognize the correct order of images during a “test” phase (simultaneous presentation of images after they had seen the images presented sequentially in a “presentation” phase (sequential presentation of images. If subjects were successfully able to execute the ordered recall task, the first trial accuracy data would appear close to 100% accuracy and it would only take one day to learn the list since the lists used were short, 3-item lists. While this study did not conclusively demonstrate monkeys are capable of ordered recall of sequentially presented, trial unique images (i.e. a list sequence presented only once per session, the data suggests that when the stimuli are not trial unique the monkeys treat each sequence as a simultaneous chaining task. A simultaneous chaining paradigm entails simultaneous presentation of all items without any previous sequential presentation of the images. It is unclear whether results resembling simultaneous chaining are seen because these animals have previous experience with simultaneous chaining, if the training procedure needs to be modified for the monkeys to understand the task, or if the task is beyond their cognitive abilities. Further research with serial learning will clarify this finding and also seek to prove whether rhesus monkeys are in fact capable of such ordered recall tasks.

  16. Mesiodistal crown diameters of the primary and permanent teeth in southern Chinese--a longitudinal study.

    Science.gov (United States)

    Yuen, K K; So, L L; Tang, E L

    1997-12-01

    The mesiodistal crown diameters of the primary and permanent teeth were measured on serial casts of 112 Hong Kong Southern Chinese (61 males and 51 females) taken at 5.68 and 12.31 years of age. None of the teeth showed significant sex difference in bilateral asymmetry, and significant bilateral asymmetry was found only for the upper primary second molars. The asymmetries were small and the sizes of the antimeres were averaged. Posterior teeth were generally less variable than anterior teeth in both dentitions in Chinese, which is contrary to other reports, but the anterior tooth of each morphological class was, in general, less variable than the posterior member. Male teeth were larger than those of females except for the lower central and lateral incisors in both dentitions, but the difference was not statistically significant. None of the primary teeth nor three of the permanent teeth were found to have significant sex differences in size. Percentage sexual dimorphism ranged from 0.06 to 1.97 per cent for the primary teeth and from 0.36 to 5.27 per cent for the permanent teeth. In the primary dentition, molars were the most dimorphic teeth in both arches, while upper incisors and lower canine were the least dimorphic teeth in their own arch. Among the permanent teeth, the canines were the most dimorphic and the incisors were among the least dimorphic teeth in both arches. Tooth sizes in both dentitions were, in general, larger than those of the Caucasians, comparable with Northern Chinese, but smaller than those of Australian Aboriginals.

  17. Comparison between powder and slices diffraction methods in teeth samples

    Energy Technology Data Exchange (ETDEWEB)

    Colaco, Marcos V.; Barroso, Regina C. [Universidade do Estado do Rio de Janeiro (IF/UERJ), RJ (Brazil). Inst. de Fisica. Dept. de Fisica Aplicada; Porto, Isabel M. [Universidade Estadual de Campinas (FOP/UNICAMP), Piracicaba, SP (Brazil). Fac. de Odontologia. Dept. de Morfologia; Gerlach, Raquel F. [Universidade de Sao Paulo (FORP/USP), Rieirao Preto, SP (Brazil). Fac. de Odontologia. Dept. de Morfologia, Estomatologia e Fisiologia; Costa, Fanny N. [Coordenacao dos Programas de Pos-Graduacao de Engenharia (LIN/COPPE/UFRJ), RJ (Brazil). Lab. de Instrumentacao Nuclear

    2011-07-01

    Propose different methods to obtain crystallographic information about biological materials are important since powder method is a nondestructive method. Slices are an approximation of what would be an in vivo analysis. Effects of samples preparation cause differences in scattering profiles compared with powder method. The main inorganic component of bones and teeth is a calcium phosphate mineral whose structure closely resembles hydroxyapatite (HAp). The hexagonal symmetry, however, seems to work well with the powder diffraction data, and the crystal structure of HAp is usually described in space group P63/m. Were analyzed ten third molar teeth. Five teeth were separated in enamel, detin and circumpulpal detin powder and five in slices. All the scattering profile measurements were carried out at the X-ray diffraction beamline (XRD1) at the National Synchrotron Light Laboratory - LNLS, Campinas, Brazil. The LNLS synchrotron light source is composed of a 1.37 GeV electron storage ring, delivering approximately 4x10{sup -1}0 photons/s at 8 keV. A double-crystal Si(111) pre-monochromator, upstream of the beamline, was used to select a small energy bandwidth at 11 keV . Scattering signatures were obtained at intervals of 0.04 deg for angles from 24 deg to 52 deg. The human enamel experimental crystallite size obtained in this work were 30(3)nm (112 reflection) and 30(3)nm (300 reflection). These values were obtained from measurements of powdered enamel. When comparing the slice obtained 58(8)nm (112 reflection) and 37(7)nm (300 reflection) enamel diffraction patterns with those generated by the powder specimens, a few differences emerge. This work shows differences between powder and slices methods, separating characteristics of sample of the method's influence. (author)

  18. Clinical evaluation of isolated abutment teeth in removable partial dentures

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    Zarrati S

    2011-02-01

    Full Text Available "nBackground and Aims: Nowadays, removable partial dentures are applied to patients who are not able to use dental implants or fixed prosthesis. Although based on the studies the users of removable partial dentures are in the risk of plaque accumulation and unacceptable changes such as gingivitis, periodontitis and mobility in abutment tooth. It is not clear whether the negative effects of removable partial dentures are more on the isolated teeth which are a kind of abutment adjacent to endentulous area in both sides. The purpose of this study was to investigate the clinical condition of isolated abutment teeth without splinting in comparison to control abutment from the aspects of B.O.P (bleeding on probing, mobility, pocket depth and gingivitis."nMaterials and Methods: In this cross-sectional study, the prepared questionnaires were filled out by 50 patients who received removable partial dentures in department of removable prosthodontics of dental school of Tehran University of Medical Sciences. The patients had isolated abutment tooth and did not have any systemic disease. The obtained data were analyzed. Using Wilcoxon, exact Fisher and Kruskal-Wallis test."nResults: B.O.P (P=0.004, pocket depth (P=0.035, and mobility (P<0.001 in isolated abutments were more than those in control abutments, but there were not significant differences in the degree of caries (P=0.083 and gingivitis (P=0.07."nConclusion: This study showed that clinical condition of isolated abutments is worse than that of control abutments. More attention should be paid to healthiness of isolated teeth without splinting and periodic follow ups should be done in these cases.

  19. Traumatic injuries to permanent teeth in Turkish children, Ankara.

    Science.gov (United States)

    Altun, Ceyhan; Ozen, Buğra; Esenlik, Elçin; Guven, Günseli; Gürbüz, Taşkin; Acikel, Cengizhan; Basak, Feridun; Akbulut, Erman

    2009-06-01

    The aim of this study was to identify the types and etiologies of dento-alveolar injuries among patients who were treated for injuries to maxillary and/or mandibular permanent teeth at the Gulhane Medical Academy, Department of Pediatric Dentistry, Center of Dental Sciences in Ankara, Turkey to provide a basis for determining optimal treatment approaches and educational needs. From a total of 4956 children aged 6-12 years (mean age: 8.91 +/- 1.95) applying to the Center, 472 children (9.5%) were found to have suffered dental injuries during a period of 2 years. Injuries were classified according to drawings and texts based on the WHO classification system, as modified by Andreasen and Andreasen. Injury rates were highest among children age 6 and ages 8-10. The most frequently injured permanent teeth were the maxillary central incisors (88.2%), and the maxillary right central permanent incisor made up 47.2% of all injured teeth. The most common cause of dental trauma was falling while walking or running (40.3%). Most injuries involved a single tooth (64.8%). The most common type of injury was enamel fracture (44.6%). There was a significant difference in gender, where boys more often suffered from a dental hard tissue and pulp injury than girls (P = 0.019), whereas there was no difference in gender (P = 0.248) in the distribution of periodontal injuries. Injuries were found to occur more frequently during the summer (P trauma, preventive orthodontic treatment in early mixed dentition may play an important role in reducing traumatic dental injuries.

  20. Microbial diversity in failed endodontic root-filled teeth

    Institute of Scientific and Technical Information of China (English)

    ZHANG Chen; HOU Ben-xiang; ZHAO Huan-ying; SUN Zheng

    2012-01-01

    Background Persistent/secondary infections of human root canals play an important role in the failure of endodontic treatment.This study used 16S rRNA sequencing to assess microbial diversity in root-filled teeth associated with failed endodontic treatment.Methods DNA was extracted from 15 teeth with persistent intraradicular infections,and the 16S rRNA of all present bacteria were amplified by PCR,followed by cloning and sequencing of the 16S rRNA amplicons.Results All sample extracts were positive for PCR amplification using the universal 16S rRNA gene primers.Negative control reactions yielded no amplicons.Sixty-five phylotypes belonging to seven phyla were identified from 760 clones; a mean of 9.4 phylotypes were detected in each sample (range 3-15).Twenty-eight phylotypes were detected in more than one sample,revealing a high inter-sample variability.Parvimonas micra (60%,9/15),Solobacterium moore (47%,7/15),Dialister invisus (33%,5/15),Enterococcus faecalis (33%,5/15),Filifactor alocis (27%,4/15),and Fusobacterium nucleatum (27%,4/15) were the prevalent species.Nineteen as-yet-uncultivated phylotypes were identified,comprising a substantial proportion of the bacteria in many cases.Conclusions Persistent intraradicular infections were present in all root-filled teeth associated with failed endodontic treatment.The current observations reveal new candidate endodontic pathogens,including as-yet-uncultivated bacteria and phylotypes that may participate in the mixed infections associated with post-treatment apical periodontitis.

  1. Isolation of Mesenchymal Stem Cells from Human Deciduous Teeth Pulp

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    Aileen I. Tsai

    2017-01-01

    Full Text Available This study aimed to identify predictors of success rate of mesenchymal stem cell (MSC isolation from human deciduous teeth pulp. A total of 161 deciduous teeth were extracted at the dental clinic of Chang Gung Memorial Hospital. The MSCs were isolated from dental pulps using a standard protocol. In total, 128 colonies of MSCs were obtained and the success rate was 79.5%. Compared to teeth not yielding MSCs successfully, those successfully yielding MSCs were found to have less severe dental caries (no/mild-to-moderate/severe: 63.3/24.2/12.5% versus 12.5/42.4/42.4%, P<0.001 and less frequent pulpitis (no/yes: 95.3/4.7% versus 51.5/48.5%, P<0.001. In a multivariate regression model, it was confirmed that the absence of dental caries (OR = 4.741, 95% CI = 1.564–14.371, P=0.006 and pulpitis (OR = 9.111, 95% CI = 2.921–28.420, P<0.001 was significant determinants of the successful procurement of MSCs. MSCs derived from pulps with pulpitis expressed longer colony doubling time than pulps without pulpitis. Furthermore, there were higher expressions of proinflammatory cytokines, interleukin- (IL- 6 and monocyte chemoattractant protein- (MCP- 1, P<0.01, and innate immune response [toll-like receptor 1 (TLR1 and TLR8, P<0.05; TLR2, TLR3, and TLR6, P<0.01] in the inflamed than noninflamed pulps. Therefore, a carious deciduous tooth or tooth with pulpitis was relatively unsuitable for MSC processing and isolation.

  2. Taxonomic attribution of the La Grive hominoid teeth.

    Science.gov (United States)

    Pérez de los Ríos, Miriam; Alba, David M; Moyà-Solà, Salvador

    2013-08-01

    The two hominoid teeth--a central upper incisor (NMB G.a.9.) and an upper molar (FSL 213981)--from the Middle Miocene site of La Grive-Saint-Alban (France) have been traditionally attributed to Dryopithecus fontani (Hominidae: Dryopithecinae). However, during the last decade discoveries in the Vallès-Penedès Basin (Spain) have shown that several hominoid genera were present in Western Europe during the late Middle Miocene. As a result, the attribution of the dryopithecine teeth from La Grive is not as straightforward as previously thought. In fact, similarities with the upper incisor of Pierolapithecus have led to suggestions that either the latter taxon is present at La Grive, or that it is a junior synonym of Dryopithecus. Here, we re-describe the La Grive teeth and critically revise their taxonomic assignment based on metrical and morphological comparisons with other Middle to Late Miocene hominoids from Europe and Turkey, with particular emphasis on those from the Vallès-Penedès Basin. Our results suggest that the I(1) differs in several respects from those of Pierolapithecus and Hispanopithecus, so that an attribution to either Dryopithecus or Anoiapithecus (for which this tooth is unknown) seems more likely. The molar, in turn, most likely corresponds to the M(1) of a female individual. Compared to other Middle Miocene taxa, its occlusal morphology enables its distinction from Pierolapithecus, whereas relative crown height agrees well with Dryopithecus. Therefore, based on available evidence, we support the traditional attribution of the La Grive hominoid to D. fontani. Copyright © 2013 Wiley Periodicals, Inc.

  3. Isolation of Mesenchymal Stem Cells from Human Deciduous Teeth Pulp

    Science.gov (United States)

    Tsai, Aileen I.; Hong, Hsiang-Hsi; Fu, Jen-Fen; Chang, Chih-Chun; Wang, I-Kuan; Huang, Wen-Hung; Weng, Cheng-Hao; Hsu, Ching-Wei

    2017-01-01

    This study aimed to identify predictors of success rate of mesenchymal stem cell (MSC) isolation from human deciduous teeth pulp. A total of 161 deciduous teeth were extracted at the dental clinic of Chang Gung Memorial Hospital. The MSCs were isolated from dental pulps using a standard protocol. In total, 128 colonies of MSCs were obtained and the success rate was 79.5%. Compared to teeth not yielding MSCs successfully, those successfully yielding MSCs were found to have less severe dental caries (no/mild-to-moderate/severe: 63.3/24.2/12.5% versus 12.5/42.4/42.4%, P < 0.001) and less frequent pulpitis (no/yes: 95.3/4.7% versus 51.5/48.5%, P < 0.001). In a multivariate regression model, it was confirmed that the absence of dental caries (OR = 4.741, 95% CI = 1.564–14.371, P = 0.006) and pulpitis (OR = 9.111, 95% CI = 2.921–28.420, P < 0.001) was significant determinants of the successful procurement of MSCs. MSCs derived from pulps with pulpitis expressed longer colony doubling time than pulps without pulpitis. Furthermore, there were higher expressions of proinflammatory cytokines, interleukin- (IL-) 6 and monocyte chemoattractant protein- (MCP-) 1, P < 0.01, and innate immune response [toll-like receptor 1 (TLR1) and TLR8, P < 0.05; TLR2, TLR3, and TLR6, P < 0.01] in the inflamed than noninflamed pulps. Therefore, a carious deciduous tooth or tooth with pulpitis was relatively unsuitable for MSC processing and isolation. PMID:28377925

  4. Nucleotide sequence of the BamHI repetitive sequence, including the HindIII fundamental unit, as a possible mobile element from the Japanese monkey Macaca fuscata.

    Science.gov (United States)

    Prassolov, V S; Kuchino, Y; Nemoto, K; Nishimura, S

    1986-01-01

    Clustered repeat units produced by BamHI digestion of genomic DNA from the Japanese monkey Macaca fuscata [JMr(BamHI)] were sequenced by dideoxy DNA sequencing. The nucleotide sequences of several individual repeats showed that the BamHI repeat contains the 170-bp HindIII element as an integral part, and that it has more than 90% homology with the HindIII repeat element [AGMr(HindIII)] found in the genomic DNA of the African green monkey. In the JMr(BamHI) repeat unit, the 170-bp HindIII element is flanked by a 6-bp inverted repeat, which is part of a 22-bp direct repeat. This latter repeat of 22-bp asymmetrically overlaps the border between the internal AGMr(HindIII)-like region and adjacent regions of the JMr(BamHI) repeat. A similar structural feature of the BamHI repeat unit has been found in the genomic DNA of the baboon, but not in that of the African green monkey. These results show clearly that the BamHI repeat of the modern Japanese monkey originated as a result of insertion of an AGMr(HindIII) element into a certain site(s) of the genomic DNA of an ancestor of the modern Japanese monkey before Macaca-Cercocebus divergence.

  5. Anterior makeover on fractured teeth by simple composite resin restoration

    Directory of Open Access Journals (Sweden)

    Eric Priyo Prasetyo

    2011-09-01

    Full Text Available Background: In daily practice dentists usually treat tooth fractures with more invasive treatments such as crown, veneer and bridges which preparation require more tooth structure removal. While currently there is trend toward minimal invasive dentistry which conserves more tooth structure. This is enhanced with the vast supply of dental materials and equipment in the market, including restorative materials. Provided with these supporting materials and equipment and greater patient’s demand for esthetic treatment, dentists must aware of the esthetics and basic principle of conserving tooth which should retain tooth longevity. Purpose: This article showed that a simple and less invasive composite resin restoration can successfully restore anterior esthetic and function of fractured teeth which generally treated with more invasive treatment options. Case: A 19 year-old female patient came with fracture on 21 and 22. This patient had a previous history of dental trauma about nine years before and was brought to a local dentist for debridement and was given analgesic, the involved teeth were not given any restorative treatment. Case management: The fractured 21 and 22 were conventionally restored with simple composite resin restoration. Conclusion: Fracture anterior teeth would certainly disturbs patient’s appearance, but these teeth could be managed conservatively and economically by simple composite resin restoration.Latar belakang: Dalam praktek sehari-hari pada umumnya dokter gigi merawat fraktur dengan restorasi invasif seperti mahkota, veneer dan jembatan yang semuanya memerlukan pengambilan jaringan gigi lebih banyak, sedangkan saat ini trend perawatan gigi lebih menuju kearah invasif minimal yang mempertahankan jaringan gigi sebanyak mungkin. Keadaan ini ditunjang oleh tersedianya berbagai macam bahan dan peralatan kedokteran gigi di pasaran, termasuk bahan restorasi. Dengan tersedianya bahan dan peralatan yang mendukung serta tingginya

  6. Bonding auto-polymerising acrylic resin to acrylic denture teeth.

    LENUS (Irish Health Repository)

    Nagle, Susan

    2009-09-01

    This study investigated the effect of surface treatments on the shear bond strength of an auto-polymerising acrylic resin cured to acrylic denture teeth. The surface treatments included a combination of grit-blasting and\\/or wetting the surface with monomer. Samples were prepared and then stored in water prior to shear testing. The results indicated that the application of monomer to the surface prior to bonding did not influence the bond strength. Grit blasting was found to significantly increase the bond strength.

  7. [Spontaneous loss of permanent teeth in children is never innocent].

    Science.gov (United States)

    Wit, M A; van der Meij, E H; Hooimeijer, L H; de Vries, T W

    2013-06-01

    A 13-year-old patient spontaneously lost tooth 47. In addition, he had for several weeks experienced numbness of the lower lip and the chin on the right side, fatigue, weakness, loss of appetite, and weight loss. After extensive investigation he seemed to be suffering from a Burkitt lymphoma. Spontaneous loss of permanent teeth in children has an extensive differential diagnosis. Dentists should be familiar with this differential diagnosis as all possible diagnoses are related to serious pathologies. The differential diagnosis includes infectious, metabolic, naplastic, and odontogenic causes. Systematic history taking, physical examination and laboratory investigations will lead to a proper diagnosis.

  8. Stress along main deformation axes in teeth of conical cutters

    Energy Technology Data Exchange (ETDEWEB)

    Ignatov, V.I.; Ignatova, N.I.

    1980-06-01

    Pairs of tension resistors are joined together with mutual axes at an orientation of 90 degrees. These pairs are then placed along the main deformation axis of the cutter tooth at 5 mm intervals and oriented towards each other at 45 degrees. Measurement results are plotted in graphs, which illustrate the fact that bending stresses in teeth along the crown are highly non-uniform, whereby the coefficient of non-uniformity for various phases of tooth engagement varies between 1.3 and 2.2. (3 refs.) (In Russian)

  9. Treatment of "non-restorable" teeth. A case report.

    Science.gov (United States)

    Donly, K J

    1991-08-01

    The purpose of this article is to present a case report of the dental care for permanent teeth that were originally considered "non-restorable". The temporary placement of stainless steel crowns was completed, followed by traditional endodontic therapy. The crowns were used as build-up matrices, access being prepared in the occlusal of the crown. Glass ionomer silver was then placed, followed by marginal finishing. Although this report is an isolated case, and is considered as temporary treatment, there may be indications to consider this technique for clinical care, on an individual basis.

  10. Immediate Desensitization in Teeth Affected by Amelogenesis Imperfecta.

    Science.gov (United States)

    Moreira, Rudá França; Figueiredo, Rossana Gomes; Oliveira, Henrique Eduardo; Fonseca, Ana Christina Lamosa da; Miranda, Mauro Sayão de

    2016-01-01

    The aim of this paper was to describe a clinical case of immediate dental desensitization using a self-etch adhesive system in an adolescent patient diagnosed with amelogenesis imperfecta (AI). AI was associated with severe tooth sensitivity, treated by the application of a universal adhesive system for desensitization of the teeth affected by AI. Reduction of tooth sensitivity was assessed using a visual analog scale during all reevaluations. The technique was effective for reducing tooth sensitivity. It was concluded that the adhesive system for tooth desensitization had an immediate effect and maintained its effectiveness during a 12-month follow-up period.

  11. Endodontic-orthodontic management of fractured anterior teeth.

    Science.gov (United States)

    Delivanis, P; Delivanis, H; Kuftinec, M M

    1978-09-01

    A case history is presented of a 10-year-old patient, who accidentally injured her maxillary central incisor. The fracture of the crown extended 2 mm below the crest of the alveolar bone. After a pulpotomy was done as a temporary measure, orthodontic appliances were placed by bonding brackets on the maxillary anterior teeth and fitting a sectional arch wire to extrude the fractured tooth. After successful extrusion, the fracture line was brought above the level of alveolar bone where successful restoration of the tooth by the acid-etch method could be accomplished.

  12. Forensic study of sex determination using PCR on teeth samples.

    OpenAIRE

    Murakami H; Yamamoto Y; Yoshitome K; Ono T; Okamoto O; Shigeta Y; Doi Y; Miyaishi S; Ishizu H

    2000-01-01

    In this study, sex determination using polymerase chain reaction (PCR) on tooth material was evaluated from the viewpoint of forensic medicine. The sensitivity of PCR for detection of the Y chromosome-specific alphoid repeat sequence and the X chromosome-specific alphoid repeat sequence was 0.5 pg of genomic DNA. Sex could be determined by PCR of DNA extracted from the pulp of 16 freshly extracted permanent teeth and dentine including the surface of the pulp cavity of 6 freshly extracted milk...

  13. In situ analysis of human teeth by external PIXE

    Energy Technology Data Exchange (ETDEWEB)

    Rautray, Tapash R., E-mail: tapash77@hotmail.co [Department of Dental Biomaterials, School of Dentistry, Kyungpook National University, 2-188-1 Samduk-dong, Jung-gu, Daegu (Korea, Republic of); ARASMIN, G. Udayagiri, Kandhamal, Orissa 762100 (India); Das, Saubhagyalaxmi [Institute of Physics, Sachivalaya Marg, Bhubaneswar 751005 (India); Rautray, Alekh C. [ARASMIN, G. Udayagiri, Kandhamal, Orissa 762100 (India)

    2010-07-15

    The elemental profiles of the enamel, cementum and caries of human teeth were analysed by the external proton induced X-ray emission studies. Ten elements namely P, Ca, V, Mn, Fe, Cu, Zn, As, Sr and Pb were estimated in the present study. P and Ca were found to be the major elements whereas all other elements were found in trace level. It was observed that the respective concentrations of elements namely P, Ca, Fe, Zn and Pb in enamel are more than those in cementum. Concentration of P ranged between 6.37% and 25% whereas Ca ranged between 12.94% and 43.36%.

  14. Considerations for ceramic inlays in posterior teeth: a review

    Science.gov (United States)

    Hopp, Christa D; Land, Martin F

    2013-01-01

    This review of ceramic inlays in posterior teeth includes a review of the history of ceramic restorations, followed by common indications and contraindications for their use. A discussion on the potential for tooth wear is followed by a review of recommended preparation design considerations, fabrication methods, and material choices. Despite the improved materials available for fabrication of porcelain inlays, fracture remains a primary mode of inlay failure. Therefore, a brief discussion on strengthening methods for ceramics is included. The review concludes with a section on luting considerations, and offers the clinician specific recommendations for luting procedures. In conclusion, inlay success rates and longevity, as reported in the literature, are summarized. PMID:23750101

  15. Transplantation of premolars as an approach for replacing avulsed teeth

    DEFF Research Database (Denmark)

    Andreasen, Jens Ove; Schwartz, Ole; Kofoed, Thomas

    2009-01-01

    . Secondly the tooth precipitates growth of the alveolar procces and allows treatment to be performed at an early age (10-12 years) where the trauma incidence is at its maximum. Finally transplanted teeth can be moved orthodontically. These characteristics make implant solutions appealing in a number...... of situations. The procedure consist in selecting a premolar in a optimal root development stage which is approximately three fourths root formation where optimal pulp and periodontal ligament healing can be achieved in more than 90 percent of the cases. The tooth is later after slight crown remodeling restored...

  16. Category of functional tooth units in relation to the number of teeth and masticatory ability in Japanese adults.

    Science.gov (United States)

    Ueno, Masayuki; Yanagisawa, Tomohito; Shinada, Kayoko; Ohara, Satoko; Kawaguchi, Yoko

    2010-02-01

    The purposes of this study were (1) to examine differences in dental status among various age groups, particularly, focusing on whether subjects retained 20 or more natural teeth, and (2) to investigate the relationship among dental status, the number and categories of functional tooth units (FTUs), and masticatory ability. A dental examination and self-administered questionnaire were conducted in a total of 2,164 residents aged 40 to 75 years who dwelt in Japan. The percentage of subjects with 20 and more natural teeth and their number of posterior teeth decreased with age. There was not much difference in the mean number of FTUs in subjects with and without 20 or more natural teeth, but those with 20 natural teeth had fewer numbers of FTUs than those with more than 20 natural teeth. The categories of the FTUs were extremely different. Subjects with 20 or more natural teeth had FTUs consisting mostly of natural to natural teeth. Subjects with 19 or fewer natural teeth had many FTUs consisting of removable prosthetic teeth. The subjective chewing ability test was significantly correlated with the number of natural teeth. Subjects could chew the higher number of test foods as the number of natural teeth increased. Not only the number of natural teeth but the categories of FTUs appear to be key factors of chewing ability. It is important to keep as many natural teeth as possible so that the person's categories of FTUs are mainly composed of natural to natural teeth to maintain better oral function.

  17. Etiology and prevention of external cervical root resorption associated to teeth bleaching

    Directory of Open Access Journals (Sweden)

    Eliane Mendes da SILVA

    2010-03-01

    Full Text Available Introduction and objective: Esthetic dentistry has been prioritizedand the desire for whiter teeth has been increasingly present in dental offices, since whiter teeth tend to indicate health, beauty, youth and a more attractive smile. Teeth bleaching is a conservative method widely used to restore the original color of darkened teeth. However, possible relations with the external cervical root resorption have concerned many researchers and clinicians. Literature review: There are many mechanisms that can activate the external cervical root resorption, such as: chemical and physical action of the bleaching materials used, morphology of the cementoenamel junction associated to the immune system, material concentration, traumas and bleaching technique used. Conclusion: Therefore, considering many factors that are still not conclusive, preventing deleterious effects on teeth and support structures, care must be taken when choosing bleaching agent and bleaching technique, as well as when selecting each case, beyond a proper restoration after teeth bleaching.

  18. Evaluation of Survival Time of Tooth Color Dental Materials in Primary Anterior Teeth

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    Behjat-Al-Molook Ajami

    2013-01-01

    Full Text Available Introduction: In restorative dentistry, selecting the proper material is an important factor for clinical success. The objective of this study was clinical evaluation of survival time of three tooth color materials in primary anterior teeth. Methods: In this interventional clinical trial study, 94 deciduous anterior teeth (36 teeth in boys, 58 teeth in girls belonging to 3-5 year old children in Pediatric Department of Mashhad Faculty of Dentistry, Iran were selected. Selective dental materials included compoglass, glass-ionomer Fuji II LC, and composite resin. The data were analyzed with Kaplan–Meyer and Log rank test. Results: compoglass had the highest survival time in comparison with composite and glass-ionomer. Nine months retention rate for teeth restored with compoglass, composite resin and glass-ionomer were estimated: 95%, 21%, and 12.5%, respectively. Conclusion: Compoglass can be a suitable material for anterior primary teeth restoration

  19. Replacement of Missing Anterior Teeth in a Patient with Temporomandibular Disorder

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    Satheesh B. Haralur

    2014-01-01

    Full Text Available The loss of anterior teeth leads to extreme psychological trauma, along with functional and esthetic debilitations. Healthy anterior teeth play an important role of protecting the posterior teeth during excursive mandibular movement. Loss of anterior teeth induces posterior interference with extended disocclusion time. Posterior disocclusion is critical to remove the harmful force on the teeth temporomandibular joint and eliminate muscle hypertonicity. Occlusal interference is considered as contributing factor to temporomandibular disorder (TMD symptoms. Prosthesis design should eliminate deleterious tooth contacts. Establishing optimum anterior guidance is a key to establishing harmonious functional occlusion in addition to the correction of the esthetic and phonetic disabilities. This case report explains the steps involved in the rehabilitation of the TMD patient with loss of maxillary anterior teeth.

  20. RICHMOND CROWN - FOR RESTORATION OF BADLY MUTILATED POSTERIOR TEETH : A CASE REPORT

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    Yadav

    2015-07-01

    Full Text Available Restoration of badly broken endodontically treated teeth is a common problem in restorative dentistry. Such teeth often require additional support from the root canal by means of a post and core restoration. In cases where tooth structure is significantly lost full coverage restorations for posterior teeth are necessary to achieve proper tooth form and function. Badly broken teeth with minimal or no crown structure require added retention and support. The Richmond crown can be a good treatment alternative for restoration of such teeth. The Richmond crown was introduced in 1878 and incorporated a threaded tube in the canal with a screw retained crown. It was later modified to eliminate the threaded tube and was redesigned as a one piece dowel and crown. This case report shows restoration of badly mutilated posterior teeth with Richmond crown.

  1. Periapical and endodontic status of permanent teeth in patients with hypophosphatemic rickets

    DEFF Research Database (Denmark)

    Andersen, Mette Guldbæk; Beck-Nielsen, Signe; Haubek, Dorte

    2012-01-01

    genetically. The aim of the present study was to describe the periapical and endodontic status of permanent teeth in patients with genetically and/or biochemically confirmed HR. The patients were recruited from a medical study on HR patients. The patients underwent a dental examination including a digital...... panoramic radiograph, which was scored for endodontically affected teeth (i.e. teeth with periapical radiolucencies and/or endodontically treated teeth). A total of 52 patients (age range: 5·7-74·5 years; 17 males and 35 females) were included. HR patients were characterised by a high number...... of endodontically affected teeth (mean: 4·2; s.d.: 5·0). The number of affected teeth rose significantly with age (P ...

  2. The study of impacted and supernumerary teeth in young man by the full mouth roentgenograms

    Energy Technology Data Exchange (ETDEWEB)

    Ahn, Hung Kyu [Department of Dental Radiology, College of Dentistry, Seoul National University, Seoul (Korea, Republic of)

    1977-11-15

    The author has observed 906 full mouth roentgenograms in Korean young man who had the impacted and supernumerary teeth. Impacted and supernumerary teeth were analysed upon several items, such as incidences and positions in the dental arch . The results were as follows; 1. The incidences of impacted teeth were 59.05%, and the ratio of upper jaw to lower one was 1:3. 2. The frequency of the supernumerary teeth were 5.52%, and the ratio of maxilla to mandible was 49:1. 3. No significant differences between right and left side in both jaws, but incidence rate of the supernumerary teeth was 74% in the maxillary central incisor area. 4. The positions of impacted and supernumerary teeth were vertical and inverted shapes in maxilla, whereas horizontal a nd mesio-angular forms in mandible.

  3. Evaluation of Survival Time of Tooth Color Dental Materials in Primary Anterior Teeth

    Directory of Open Access Journals (Sweden)

    Taraneh Movahhed

    2012-09-01

    Full Text Available Introduction: In restorative dentistry, selecting the proper material is an important factor for clinical success. The objective of this study was clinical evaluation of survival time of three tooth color materials in primary anterior teeth. Methods: In this interventional clinical trial study, 94 deciduous anterior teeth (36 teeth in boys, 58 teeth in girls belonging to 3-5 year old children in Pediatric Department of Mashhad Faculty of Dentistry, Iran were selected. Selective dental materials included compoglass, glass-ionomer Fuji II LC, and composite resin. The data were analyzed with Kaplan–Meyer and Log rank test. Results: compoglass had the highest survival time in comparison with composite and glass-ionomer. Nine months retention rate for teeth restored with compoglass, composite resin and glass-ionomer were estimated: 95%, 21%, and 12.5%, respectively. Conclusion: Compoglass can be a suitable material for anterior primary teeth restoration.

  4. Teeth grinding, oral motor performance and maximal bite force in cerebral palsy children.

    Science.gov (United States)

    Botti Rodrigues Santos, Maria Teresa; Duarte Ferreira, Maria Cristina; de Oliveira Guaré, Renata; Guimarães, Antonio Sergio; Lira Ortega, Adriana

    2015-01-01

    Identify whether the degree of oral motor performance is related to the presence of teeth grinding and maximal bite force values in children with spastic cerebral palsy. Ninety-five spastic cerebral palsy children with and without teeth grinding, according to caregivers' reports, were submitted to a comprehensive oral motor performance evaluation during the feeding process using the Oral Motor Assessment Scale. Maximal bite force was measured using an electronic gnathodynamometer. The teeth grinding group (n = 42) was younger, used anticonvulsant drugs, and was more frequently classified within the subfunctional oral motor performance category. Teeth grinding subfunctional spastic cerebral palsy children presented lower values of maximal bite force. The functional groups showing the presence or absence of teeth grinding presented higher values of maximal bite force compared with the subfunctional groups. In spastic cerebral palsy children, teeth grinding is associated with the worse oral motor performance. © 2015 Special Care Dentistry Association and Wiley Periodicals, Inc.

  5. Effect of physical and chemical factors on Macaca Mulatta′s pulp and change of the collagen in pulp%理化因素刺激对牙髓及其胶原 影响的实验研究

    Institute of Scientific and Technical Information of China (English)

    袁理; 岳林; 毛秀萍; 高岩

    2001-01-01

    Objective To investigate the change of pulp and its collagen to outside stimuli. Methods 51 permanent teeth from 10 adult healthy Macaca Mulatta′s monkeys were chosen as experimental teeth. 39 of them were prepared Class V cavities. The teeth were divided into two groups, one was filled with zinc phosphate cement and another group with zinc oxide eugenol. A blank control group of 12 teeth was set at the same time. Just after the operation, 3 d, 7 d, 1 month and 3 months later, the animals were executed. Histologic changes were evaluated by means of HE and collagen staining method. Results Local inflammation was the major representation in the pulps of the zinc phosphate cement group from 7d to 3 months after operation. The percentage of collagen decrease dropped sharply,and there was no inflammation cells infiltration in the pulps of zinc oxide eugenol group from 1 to 3 months after operation. By means of collagen staining method, the morphological characters ,distribution and the change of pulpal collagen during a certain pathologic process were clearly represented in histologic slices. The change of collagen appeared earlier than the inflammation cells infiltration. Conclusions Zinc phosphate cement can lead to medium inflammation of the pulp. The change of collagen appears earlier than that of WBC, which can be used as a sensitive indicator.%目的了解猴牙髓及其胶原对物理、化学刺激的反应。方法观察磷酸锌粘固剂及氧化锌丁香油酚粘固剂(zinc oxide eugenol,ZOE)间接盖髓后,恒河猴牙髓即刻、3 d、7 d、1个月、3个月HE和胶原特殊染色后的组织学变化。结果①磷酸锌粘固剂组术后7 d~3个月,牙髓以局限性炎症损伤为主;②ZOE组术后1~3个月胶原减少明显下降,已无炎症细胞浸润;③胶原特殊染色法可清楚地反映牙髓胶原的形态特点、分布及变化,术后3 d胶原明显减少早于炎症细胞的出现。结论磷酸锌粘固剂对

  6. An observational study of the frequency of supernumerary teeth in a population of 2000 patients

    OpenAIRE

    Leco Berrocal, María Isabel; Martín Morales, José F.; Martínez González, José María

    2007-01-01

    An evaluation is made of the epidemiological characteristics of supernumerary teeth, with an analysis of the associated clinical-eruptive complications. A longitudinal observational study was made of 2000 patients, with the documentation of demographic data, the presence of supernumerary teeth, their location, mechanical accidents and the presence of associated pathology. The presence of supernumerary teeth was recorded in 1.05% of the study subjects (mean age 20.2 years), with a greater freq...

  7. Potentiometric stripping analysis of lead and cadmium leaching from dental prosthetic materials and teeth

    OpenAIRE

    GORAN M. NIKOLIC; BILJANA M. KALICANIN; RUZICA S. NIKOLIC

    2004-01-01

    Potentiometric stipping analysis (PSA) was applied for the determination of lead and cadmium leaching from dental prosthetic materials and teeth. The soluble lead content in finished dental implants was found to be much lower than that of the individual components used for their preparation. Cadmium was not detected in dental implants and materials under the defined conditions. The soluble lead and cadmium content of teeth was slightly lower than the lead and cadmium content in whole teeth (w...

  8. Scanning electron microscopy and calcification in amelogenesis imperfecta in anterior and posterior human teeth

    OpenAIRE

    Sánchez-Quevedo, M. C.; Ceballos, G.; García, J. M.; Rodriguez, I. A.; Gómez de Ferraris, M. E.; Campos, Antonio

    2001-01-01

    Teeth fragments from members of a famil? clinically and genetically diagnosed as having amelogenesis imperfecta were studied by scanning electron microscopy and X-ray microprobe analysis to establish the morphological patterns and the quantitative concentration of calcium in the enamel of anterior (canine, incisor) and posterior (premolar and molar) teeth. The prism patterns in the enamel of teeth from both regions were parallel or irregularly decussate, with ...

  9. Phenotypic and growth characterization of human mesenchymal stem cells cultured from permanent and deciduous teeth

    Directory of Open Access Journals (Sweden)

    Revathi Shekar

    2012-01-01

    Conclusions: Permanent and deciduous teeth are both viable sources of stem cells. The permanent teeth were easier to culture because of a lower chance of contamination with oral microflora. The growth characteristics of the cells obtained from both these sources were similar. However, there was a difference in the ratio of fibroblastoid cells to epithelioid cells between the cultures obtained from the permanent and deciduous teeth.

  10. Evaluation of enamel damages following orthodontic bracket debonding in fluorosed teeth bonded with adhesion promoter

    OpenAIRE

    Baherimoghadam, Tahreh; Akbarian, Sahar; Rasouli, Reza; Naseri, Navid

    2016-01-01

    Objective: To evaluate shear bond strength (SBS) of the orthodontic brackets bonded to fluorosed and nonfluorosed teeth using Light Bond with and without adhesion promoters and compare their enamel damages following debonding. Materials and Methods: In this study, 30 fluorosed (Thylstrup and Fejerskov Index = 4?5) and 30 nonfluorosed teeth were randomly distributed between two subgroups according to the bonding materials: Group 1, fluorosed teeth bonded with Light Bond; Group 2, fluorosed tee...

  11. Non-syndrome associated multiple supernumerary teeth: A report of two cases

    Directory of Open Access Journals (Sweden)

    Nayak Ullal

    2006-05-01

    Full Text Available Multiple supernumerary teeth are usually associated with syndromes. On the contrary, multiple supernumerary teeth without association with any syndromes are very rare. This article presents a report of two cases with multiple supernumerary teeth not associated with any syndrome and emphasizes the routine advice of orthopantomogram whenever a single supernumerary tooth is detected irrespective of whether the patient has any syndrome or not.

  12. A new understanding of oral and dental pathology of the equine cheek teeth.

    Science.gov (United States)

    Casey, Miriam

    2013-08-01

    Equine dental disease has a high prevalence. Because of developmental, functional, and anatomic differences, limited inference can be made from brachydont dental pathology to that of equine cheek teeth. This article reviews the pathology of equine cheek teeth and their associated oral tissues, with specific information on periodontitis, pulpitis, maxillary infundibular changes, dental fractures, dental overgrowths, mucosal ulceration, and the regenerative capacity of equine teeth.

  13. Cultural alteration of human teeth in the Mariana Islands.

    Science.gov (United States)

    Ikehara-Quebral, R; Douglas, M T

    1997-11-01

    Evidence of cultural dental modification in a precontact (pre-1521) skeletal sample from the Academy of Our Lady of Guam gymnasium site in Agana, Guam, is documented. Two of the four individuals recovered at the Academy Gym site exhibit modification of the maxillary teeth. One individual displays vertical incising of a single tooth, and the other exhibits horizontal abrading of the anterior teeth which may be a purposeful or an incidental alteration. Although deliberate alteration of the dentition, including tooth extraction, notching, filing, and drilling, has been documented in human groups worldwide, little has been written about these cultural practices in the Mariana Islands. Examination of the available literature on precontact human remains from the region reveals at least three patterns of dental incising and similar cases of dental abrasion. While the origins of these practices are not known, the presence and style of these cultural alterations may be sex-specific, cosmetic in nature, or an indication of status in a ranked society. Alternatively, they may signify membership in a particular group or lineage, or mark a rite of passage. Because the comparative samples are limited in number and small, and the provenience of many of the skeletons is obscure, temporal variation cannot be ruled out.

  14. A study on the mixed jaw lesions associated with teeth

    Energy Technology Data Exchange (ETDEWEB)

    Nah, Kyung Soo [Dept. of Dental Radiology, College of Dentistry, Pusan National University, Pusan (Korea, Republic of)

    2000-03-15

    1. Retrospectively evaluate the accuracy of tentative diagnosis or impression from the clinico-radiographic materials of jaw lesions which showed mixed lesions associated with teeth. 2. To observe the diagnostic importance of the calcified part of the lesions which appear as radiopaque areas. 14 cases of jaw lesions which showed mixed lesions associated with teeth were reviewed. These lesions were mostly diagnosed as adenomatoid odontogenic tumors (6 cases) or calcifying odontogenic cysts with (4 cases) or without odontomas (4 cases). The calcified elements of the lesions which demonstrated various sizes and patterns of radiopaque shadows resembled odontoid tissues in some cases but could not be defined in some other cases radiographically. The final histopathologic diagnosis confirmed adenomatoid odontogenic tumors in 4 of the 6 cases. The remaining 2 cases turned out to be odontoma and ameloblastic fibroodontoma. The 4 cases of calcifying odontogenic cysts with odontomas were correct in 3 cases but remaining 1 case was just odontoma. The 4 cases of calcifying odontogenic cysts were proved to be odontogenic keratocyst, calcified peripheral fibroma, unicystic ameloblastoma and squamous cell carcinoma. The diagnostic accuracy of the adenomatoid odontogenic tumors and calcifying odontogenic cysts were high when the lesions show typical appearance. The calcifications which show radiopaque areas could be odontomas or dystrophic calficifations or remnants of bone fragments from resorption.

  15. Dentin Topographic Features following Chemomechanical Caries Removal in Primary Teeth.

    Science.gov (United States)

    Kotb, R M; Elkateb, M A; Ahmed, A M; Kawana, K Y; El Meligy, O A

    Study the topographic features of dentin after caries removal with a chemomechanical agent (Papacarie) compared with the conventional drilling method. The sample included 7 exfoliated and extracted primary teeth with carious dentin lesions, not reaching the pulp. Each tooth was sectioned longitudinally through the center of the carious lesions into two halves. The teeth were then divided into two groups according to the method of caries removal. Following caries removal, dentin topography and the cut section were examined using the scanning electron microscope. Papacarie produced an irregular, porous, rough and globular dentin appearance. The dentin surfaces were generally free of smear layer, visible bacteria and the dentinal tubules were opened. The dentin cut surfaces showed patent dentinal tubules with open orifices. The drilling method created a smooth and amorphous surface with a continuous smear layer occluding the dentinal tubules. Numerous bacteria were also observed. The cut dentin surfaces showed patent dentinal tubules with their orifices plugged with smear layer. Papacarie produced a rough and porous surface with partial or complete removal of the smear layer and opened dentinal tubules, while the drill produced a smooth surface with uniform smear layer occluding the dentinal tubules.

  16. Predicting Agenesis of the Mandibular Second Premolar from Adjacent Teeth.

    Directory of Open Access Journals (Sweden)

    Geetanjali Sharma

    Full Text Available Early diagnosis of agenesis of the mandibular second premolar (P2 enhances management of the dental arch in the growing child. The aim of this study was to explore the relationship in the development of the mandibular first molar (M1 and first premolar (P1 at early stages of P2 (second premolar. Specifically, we ask if the likelihood of P2 agenesis can be predicted from adjacent developing teeth. We selected archived dental panoramic radiographs with P2 at crown formation stages (N = 212 and calculated the likelihood of P2 at initial mineralisation stage 'Ci' given the tooth stage of adjacent teeth. Our results show that the probability of observing mandibular P2 at initial mineralisation stage 'Ci' decreased as both the adjacent P1 and M1 matured. The modal stage at P2 'Ci' was P1 'Coc' (cusp outline complete and M1 'Crc' (crown complete. Initial mineralisation of P2 was observed up to P1 'Crc' and M1 stage 'R½' (root half. The chance of observing P2 at least 'Coc' (coalescence of cusps was considerably greater prior to these threshold stages compared to later stages of P1 and M1. These findings suggest that P2 is highly unlikely to develop if P1 is beyond 'Crc' and M1 is beyond 'R½'.

  17. Bond strength with various etching times on young permanent teeth

    Energy Technology Data Exchange (ETDEWEB)

    Wang, W.N.; Lu, T.C. (School of Dentistry, National Defense Medical Center, Taipei, Taiwan (China))

    1991-07-01

    Tensile bond strengths of an orthodontic resin cement were compared for 15-, 30-, 60-, 90-, or 120-second etching times, with a 37% phosphoric acid solution on the enamel surfaces of young permanent teeth. Fifty extracted premolars from 9- to 16-year-old children were used for testing. An orthodontic composite resin was used to bond the bracket directly onto the buccal surface of the enamel. The tensile bond strengths were tested with an Instron machine. Bond failure interfaces between bracket bases and teeth surfaces were examined with a scanning electron microscope and calculated with mapping of energy-dispersive x-ray spectrometry. The results of tensile bond strength for 15-, 30-, 60-, or 90-second etching times were not statistically different. For the 120-second etching time, the decrease was significant. Of the bond failures, 43%-49% occurred between bracket and resin interface, 12% to 24% within the resin itself, 32%-40% between resin and tooth interface, and 0% to 4% contained enamel fragments. There was no statistical difference in percentage of bond failure interface distribution between bracket base and resin, resin and enamel, or the enamel detachment. Cohesive failure within the resin itself at the 120-second etching time was less than at other etching times, with a statistical significance. To achieve good retention, to decrease enamel loss, and to reduce moisture contamination in the clinic, as well as to save chairside time, a 15-second etching time is suggested for teenage orthodontic patients.

  18. Pulp revascularization of immature dog teeth with apical periodontitis.

    Science.gov (United States)

    Thibodeau, Blayne; Teixeira, Fabricio; Yamauchi, Mitsuo; Caplan, Daniel J; Trope, Martin

    2007-06-01

    This study examined the ability of a collagen solution to aid revascularization of necrotic-infected root canals in immature dog teeth. Sixty immature teeth from 6 dogs were infected, disinfected, and randomized into experimental groups: 1: no further treatment; 2: blood in canal; 3: collagen solution in canal, 4: collagen solution + blood, and 5: negative controls (left for natural development). Uncorrected chi-square analysis of radiographic results showed no statistical differences (p >or= 0.05) between experimental groups regarding healing of radiolucencies but a borderline statistical difference (p = 0.058) for group 1 versus group 4 for radicular thickening. Group 2 showed significantly more apical closure than group 1 (p = 0.03) and a borderline statistical difference (p = 0.051) for group 3 versus group 1. Uncorrected chi-square analysis revealed that there were no statistical differences between experimental groups for histological results. However, some roots in each of groups 1 to 4 (previously infected) showed positive histologic outcomes (thickened walls in 43.9%, apical closure in 54.9%, and new luminal tissue in 29.3%). Revascularization of disinfected immature dog root canal systems is possible.

  19. Modularity of the rodent mandible: integrating bones, muscles, and teeth.

    Science.gov (United States)

    Zelditch, Miriam Leah; Wood, Aaron R; Bonett, Ronald M; Swiderski, Donald L

    2008-01-01

    Summary Several models explain how a complex integrated system like the rodent mandible can arise from multiple developmental modules. The models propose various integrating mechanisms, including epigenetic effects of muscles on bones. We test five for their ability to predict correlations found in the individual (symmetric) and fluctuating asymmetric (FA) components of shape variation. We also use exploratory methods to discern patterns unanticipated by any model. Two models fit observed correlation matrices from both components: (1) parts originating in same mesenchymal condensation are integrated, (2) parts developmentally dependent on the same muscle form an integrated complex as do those dependent on teeth. Another fits the correlations observed in FA: each muscle insertion site is an integrated unit. However, no model fits well, and none predicts the complex structure found in the exploratory analyses, best described as a reticulated network. Furthermore, no model predicts the correlation between proximal parts of the condyloid and coronoid, which can exceed the correlations between proximal and distal parts of the same process. Additionally, no model predicts the correlation between molar alveolus and ramus and/or angular process, one of the highest correlations found in the FA component. That correlation contradicts the basic premise of all five developmental models, yet it should be anticipated from the epigenetic effects of mastication, possibly the primary morphogenetic process integrating the jaw coupling forces generated by muscle contraction with those experienced at teeth.

  20. Dental caries - not just holes in teeth! A perspective.

    Science.gov (United States)

    Bowen, W H

    2016-06-01

    Cavitation in teeth results from a pathogenic process termed dental caries that has occurred on the tooth surface for weeks or even years. Accumulation of dental plaque (biofilm) on the tooth is usually the first manifestation of the disease. Although acid production is the immediate and proximal cause of dissolution of teeth; it is the milieu within which the acid is formed that should be of primary concern. Focusing on the 'critical pH' has detracted attention from the more biological aspects (biofilm formation) of dental caries. Dental caries is unique; it is a biological process occurring on essentially an inert surface. Investigation of the multitude of interactions occurring in plaque ranging from enamel interfaces to surfaces of bacteria and matrices poses challenges worthy of the best scientific minds. The mouth clearly offers unique opportunities to investigate the multi facets of biofilm formation in vivo, generating data that have relevance way beyond the mouth. Prevention of this ubiquitous disease, dental caries, continues to present serious challenges. The public health benefits of fluoride delivered in its various formats are well recognized. Nevertheless, additional preventive approaches are required. Overcoming the rapid clearance of agents from the mouth is particularly challenging. Building on the polymerizing capacity of glucosyltransferases it may be possible to incorporate a therapeutic agent into the matrix plaque, thereby delivering therapeutic agents precisely to where they are needed. © 2015 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.