WorldWideScience

Sample records for mac levels defined

  1. Serum Mac-2 binding protein levels as a novel diagnostic biomarker for prediction of disease severity and nonalcoholic steatohepatitis.

    Science.gov (United States)

    Kamada, Yoshihiro; Fujii, Hideki; Fujii, Hironobu; Sawai, Yoshiyuki; Doi, Yoshinori; Uozumi, Naofumi; Mizutani, Kayo; Akita, Maaya; Sato, Motoya; Kida, Sachiho; Kinoshita, Noriaki; Maruyama, Nobuhiro; Yakushijin, Takayuki; Miyazaki, Masanori; Ezaki, Hisao; Hiramatsu, Naoki; Yoshida, Yuichi; Kiso, Shinichi; Imai, Yasuharu; Kawada, Norifumi; Takehara, Tetsuo; Miyoshi, Eiji

    2013-10-01

    Mac-2 binding protein (Mac-2 bp) is one of the major fucosylated glycoproteins, which we identified with glycol-proteomic analyses. We previously reported that fucosylated glycoproteins are secreted into bile, but scarcely secreted into sera in normal liver and hypothesized that the fucosylation-based sorting machinery would be disrupted in ballooning hepatocytes due to the loss of cellular polarity. In the present study, we investigated the availability of Mac-2 bp for differential diagnosis of nonalcoholic steatohepatitis (NASH) from nonalcoholic fatty liver disease (NAFLD) as a biomarker. Serum Mac-2 bp levels were determined with our developed ELISA kit. Our cohort of 127 patients with NAFLD had liver biopsy to make a histological diagnosis of NASH and simple fatty liver. Mac-2 bp levels were significantly elevated in NASH patients compared with non-NASH (simple steatosis) patients (2.132 ± 1.237 vs. 1.103 ± 0.500 μg/mL, p Mac-2 bp was 0.816. Moreover, multivariate logistic regression analyses showed Mac-2 bp levels could predict the fibrosis stage and the presence of ballooning hepatocytes in NAFLD patients. These results support the potential usefulness of measuring Mac-2 bp levels in clinical practice as a biomarker for NASH. © 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  2. LFA-1 and Mac-1 define characteristically different intralumenal crawling and emigration patterns for monocytes and neutrophils in situ.

    Science.gov (United States)

    Sumagin, Ronen; Prizant, Hen; Lomakina, Elena; Waugh, Richard E; Sarelius, Ingrid H

    2010-12-01

    To exit blood vessels, most (∼80%) of the lumenally adhered monocytes and neutrophils crawl toward locations that support transmigration. Using intravital confocal microscopy of anesthetized mouse cremaster muscle, we separately examined the crawling and emigration patterns of monocytes and neutrophils in blood-perfused unstimulated or TNF-α-activated venules. Most of the interacting cells in microvessels are neutrophils; however, in unstimulated venules, a greater percentage of the total monocyte population is adherent compared with neutrophils (58.2 ± 6.1% versus 13.6 ± 0.9%, adhered/total interacting), and they crawl for significantly longer distances (147.3 ± 13.4 versus 61.8 ± 5.4 μm). Intriguingly, after TNF-α activation, monocytes crawled for significantly shorter distances (67.4 ± 9.6 μm), resembling neutrophil crawling. Using function-blocking Abs, we show that these different crawling patterns were due to CD11a/CD18 (LFA-1)- versus CD11b/CD18 (Mac-1)-mediated crawling. Blockade of either Mac-1 or LFA-1 revealed that both LFA-1 and Mac-1 contribute to monocyte crawling; however, the LFA-1-dependent crawling in unstimulated venules becomes Mac-1 dependent upon inflammation, likely due to increased expression of Mac-1. Mac-1 alone was responsible for neutrophil crawling in both unstimulated and TNF-α-activated venules. Consistent with the role of Mac-1 in crawling, Mac-1 block (compared with LFA-1) was also significantly more efficient in blocking TNF-α-induced extravasation of both monocytes and neutrophils in cremaster tissue and the peritoneal cavity. Thus, mechanisms underlying leukocyte crawling are important in regulating the inflammatory responses by regulating the numbers of leukocytes that transmigrate.

  3. Control of System with Defined Risk Level

    Directory of Open Access Journals (Sweden)

    Pavol Tomasov

    2002-01-01

    Full Text Available In the following paper the basic requirements for system control with defined risk level is presented. The paper should be an introduction to describe of theoretical apparatus, which was created during some years of research work in the Department of information and safety systems in this area. It a modification or creation of new parts of Information theory, System theory, and Control theory means. This parts are necessary for the analysis and synthesis tasks in the systems where dominant attribute of control is defined risk level. The basic problem is the creation of protect mechanism again the threats from inside and from controlled system environs. For each risk reduction mechanism is needed some redundancy which should be into control algorithm to put by exactly determined way.

  4. Mac Bible

    CERN Document Server

    Spivey, Dwight

    2009-01-01

    This essential guide answers all your questions on using a Macintosh computer, whether you?re unpacking your very first Mac after switching from a PC or upgrading from an older Mac. You?ll walk through all pre-installed Mac applications, including using Mac OS X, browsing the Web using Safari, downloading music from the iTunes store, troubleshooting Mac-specific problems, organizing photos in iPhoto, organizing calendars in iCal, editing digital video in iMovie, and more.

  5. Defining and using open architecture levels

    Science.gov (United States)

    Cramer, M. A.; Morrison, A. W.; Cordes, B.; Stack, J. R.

    2012-05-01

    Open architecture (OA) within military systems enables delivery of increased warfighter capabilities in a shorter time at a reduced cost.i In fact in today's standards-aware environment, solutions are often proposed to the government that include OA as one of its basics design tenets. Yet the ability to measure and assess OA in an objective manner, particularly at the subsystem/component level within a system, remains an elusive proposition. Furthermore, it is increasingly apparent that the establishment of an innovation ecosystem of an open business model that leverages thirdparty development requires more than just technical modifications that promote openness. This paper proposes a framework to migrate not only towards technical openness, but also towards enabling and facilitating an open business model, driven by third party development, for military systems. This framework was developed originally for the U.S. Navy Littoral and Mine Warfare community; however, the principles and approach may be applied elsewhere within the Navy and Department of Defense.

  6. Level-0 structure of level-1 U$_{q}$($\\widehat{s}\\widehat{l}_{2}$)-modules and MacDonald polynomials

    CERN Document Server

    Jimbo, M; Konno, H; Miwa, T; Petersen, J U H

    1995-01-01

    The level-1 integrable highest weight modules of U_q(\\widehat{sl}_2) admit a level-0 action of the same algebra. This action is defined using the affine Hecke algebra and the basis of the level-1 module generated by components of vertex operators. Each level-1 module is a direct sum of finite-dimensional irreducible level-0 modules, whose highest weight vector is expressed in terms of Macdonald polynomials. This decomposition leads to the fermionic character formula for the level-1 modules.

  7. Increased levels of serum Wisteria floribunda agglutinin-positive Mac-2 binding protein in idiopathic pulmonary fibrosis.

    Science.gov (United States)

    Kono, Masato; Nakamura, Yutaro; Oyama, Yoshiyuki; Mori, Kazutaka; Hozumi, Hironao; Karayama, Masato; Hashimoto, Dai; Enomoto, Noriyuki; Fujisawa, Tomoyuki; Inui, Naoki; Yamada, Masaomi; Hamada, Etsuko; Colby, Thomas V; Maekawa, Masato; Suda, Takafumi

    2016-06-01

    Mac-2 binding protein (M2BP) is a cell-adhesive glycoprotein of the extracellular matrix secreted as a ligand of galectin-3 (Mac-2). Recently, a Wisteria floribunda agglutinin positive-M2BP (WFA(+)-M2BP) assay developed using a lectin-antibody sandwich immunoassay has shown promise as a new fibrotic marker in liver fibrosis to detect unique fibrosis-related glycoalteration. The aim of this study is to evaluate the utility of serum WFA(+)-M2BP levels in patients with idiopathic pulmonary fibrosis (IPF). We measured serum WFA(+)-M2BP levels in 116 patients with IPF and 42 healthy volunteers. We examined the relationship between serum WFA(+)-M2BP levels and clinical parameters and further investigated the prognostic significance of serum WFA(+)-M2BP levels in patients with IPF. Serum WFA(+)-M2BP levels were significantly higher in patients with IPF than in healthy controls (1.09 ± 0.89 cutoff index [COI], 0.57 ± 0.24 COI, respectively; P reticulation and honeycombing scores in HRCT, and fibrotic foci scores in pathological findings, and a significant negative correlation was found between serum WFA(+)-M2BP levels and FVC, %DLco and macrophages in BAL. Furthermore, patients with high serum WFA(+)-M2BP levels had a significantly worse prognosis than those with low levels (log-rank test, P = 0.0209), and a high serum WFA(+)-M2BP level was a significant prognostic factor in Cox proportional hazards regression analysis. Our results suggest that the serum WFA(+)-M2BP level is a potential biomarker in patients with IPF. Copyright © 2016 Elsevier Ltd. All rights reserved.

  8. Identification of Children with Language Impairment: Investigating the Classification Accuracy of the MacArthur-Bates Communicative Development Inventories, Level III

    Science.gov (United States)

    Skarakis-Doyle, Elizabeth; Campbell, Wenonah; Dempsey, Lynn

    2009-01-01

    Purpose: This study tested the accuracy with which the MacArthur-Bates Communicative Development Inventories, Level III (CDI-III), a parent report measure of language ability, discriminated children with language impairment from those developing language typically. Method: Parents of 58 children, 49 with typically developing language (age 30 to 42…

  9. Study on parallel two-level polling cont rol based MAC protocol for Wireless sensor networks%并行调度两级轮询控制传感器网络 MAC 协议分析

    Institute of Scientific and Technical Information of China (English)

    官铮; 邹丹; 丁洪伟; 钱文华

    2014-01-01

    Aiming at the delay-sensitive applications with an unbalanced property of network flow , a new protocol called the parallel two-level polling control based MAC ( PTLP-MAC) is proposed in this paper .The PTLP-MAC provides priority distinction from the aspects of the polling route and service scheme assignment .By proceeding with the data transmission and request parallel , the mean waiting time of the data packet is further reduced. Further-more, by use of the embedded Markov chain and the theory of probability generating function , the mathematical functions were established and closed form expressions were given for obtaining the mean cyclic period , as well as the mean queue length and the mean waiting time characteristics .The analytical results were also verified through extensive computer simulations .%针对具有网络流量非均衡特性的时延敏感业务,提出一种并行调度两级轮询MAC控制协议。协议从服务策略和服务路径的角度实现了节点的优先级区分,并且通过服务过程和查询转换过程的并行处理,使得系统的时延特性显著提高。采用嵌入式马尔可夫链和概率母函数理论对提出的协议进行数学建模分析,精确解析了系统的平均排队队长、平均循环周期、信息分组的平均等待时延,仿真实验表明理论分析的正确性以及协议的有效性。

  10. Defining Medical Levels of Care for Exploration Missions

    Science.gov (United States)

    Hailey, M.; Reyes, D.; Urbina, M.; Rubin, D.; Antonsen, E.

    2017-01-01

    NASA medical care standards establish requirements for providing health and medical programs for crewmembers during all phases of a mission. These requirements are intended to prevent or mitigate negative health consequences of long-duration spaceflight, thereby optimizing crew health and performance over the course of the mission. Current standards are documented in the two volumes of the NASA-STD-3001 Space Flight Human-System Standard document, established by the Office of the Chief Health and Medical Officer. Its purpose is to provide uniform technical standards for the design, selection, and application of medical hardware, software, processes, procedures, practices, and methods for human-rated systems. NASA-STD-3001 Vol. 1 identifies five levels of care for human spaceflight. These levels of care are accompanied by several components that illustrate the type of medical care expected for each. The Exploration Medical Capability (ExMC) of the Human Research Program has expanded the context of these provided levels of care and components. This supplemental information includes definitions for each component of care and example actions that describe the type of capabilities that coincide with the definition. This interpretation is necessary in order to fully and systematically define the capabilities required for each level of care in order to define the medical requirements and plan for infrastructure needed for medical systems of future exploration missions, such as one to Mars.

  11. Analisis Performansi Algoritma Penjadwalan Log Rule dan Frame Level Schedule Skenario Multicell Pada Layer Mac LTE

    Directory of Open Access Journals (Sweden)

    Ridwan

    2016-03-01

    Full Text Available Mobile telecommunications technology gradually evolved to support better services such as voice, data, and video to users of telecommunications services. LTE (Long Term Evolution is a network based on Internet Protocol (IP standardized by 3rd Generation Partnership Project (3GPP. To support it, LTE requires a mechanism that can support. One of them by applying methods of scheduling packets in each service. Scheduling is a different treatment to packets that come in accordance with the priorities of the scheduling algorithm. In this research, to analyze the performance of LTE with paramater delay, packet loss ratio, throughput and fairness index uses a scheduling algorithms Frame Level Schedule (FLS and Log Rule on LTE-Simulator with scenarios using Voip traffic, Video and Best Effort (BE. The results is scheduling algorithms FLS is better than log rule in term of throughput values, while of scheduling algorithms log rule is better than FLS in terms of delay based on the number and speed of the users. This indicates that both scheduling algorithms suitable for use in LTE networks within conditions of traffic real time services, but not for non real time services such as BE.

  12. Macs for dummies

    CERN Document Server

    Baig, Edward C

    2014-01-01

    Get the most out of your Mac with this comprehensive guide Macs For Dummies, 13th Edition is the ultimate guide to your Mac, fully updated to include information about the latest updates. The book walks you through troubleshooting, syncing mobile devices, integrating Windows, and more, so you can take advantage of everything Macs have to offer. Whether you're a new user, a recent convert, or you just want to get the most out of your Mac, this book puts all the information you need in one place. Discover what makes Macs superior computing machines. Learn the basics, from mastering the Dock and

  13. Windows for Intel Macs

    CERN Document Server

    Ogasawara, Todd

    2008-01-01

    Even the most devoted Mac OS X user may need to use Windows XP, or may just be curious about XP and its applications. This Short Cut is a concise guide for OS X users who need to quickly get comfortable and become productive with Windows XP basics on their Macs. It covers: Security Networking ApplicationsMac users can easily install and use Windows thanks to Boot Camp and Parallels Desktop for Mac. Boot Camp lets an Intel-based Mac install and boot Windows XP on its own hard drive partition. Parallels Desktop for Mac uses virtualization technology to run Windows XP (or other operating systems

  14. Enterprise Mac administrators guide

    CERN Document Server

    Smith, William

    2015-01-01

    IT departments everywhere will be integrating Macs and Mac OS X into their IT infrastructure and this book will tell them how to do it. It will serve as an authoritative, useful and frequently referenced book on Mac OS X administration.

  15. Defining Levels of Learning for Strengths Development Programs in Pharmacy

    Directory of Open Access Journals (Sweden)

    Kristin K. Janke, Ph.D.

    2010-01-01

    Full Text Available The Clifton StrengthsFinder® is an online measure of personal talent that identifies where an individual’s greatest potential for building strengths exists. This paper describes a framework for strengths education in pharmacy which includes introductory, intermediate and advanced levels of learning. The use of the StrengthsFinder® assessment and supporting workshops aids student pharmacists, pharmacy residents and practitioners in identifying and refining their talents and connecting talents to roles in the profession. Additional learning strategies support a learner’s progression to intermediate and advanced levels of learning, which focus on the application of strengths in teams, leadership, and organizational development. By articulating and recognizing levels of learning around strengths-related content and skills, strong instructional design is fostered. Optimal design includes development of a sequence of learning opportunities delivered over time, a roll-out plan and consideration of the instructional resources required.

  16. Vehicle Health Management Communications Requirements for AeroMACS

    Science.gov (United States)

    Kerczewski, Robert J.; Clements, Donna J.; Apaza, Rafael D.

    2012-01-01

    As the development of standards for the aeronautical mobile airport communications system (AeroMACS) progresses, the process of identifying and quantifying appropriate uses for the system is progressing. In addition to defining important elements of AeroMACS standards, indentifying the systems uses impacts AeroMACS bandwidth requirements. Although an initial 59 MHz spectrum allocation for AeroMACS was established in 2007, the allocation may be inadequate; studies have indicated that 100 MHz or more of spectrum may be required to support airport surface communications. Hence additional spectrum allocations have been proposed. Vehicle health management (VHM) systems, which can produce large volumes of vehicle health data, were not considered in the original bandwidth requirements analyses, and are therefore of interest in supporting proposals for additional AeroMACS spectrum. VHM systems are an emerging development in air vehicle safety, and preliminary estimates of the amount of data that will be produced and transmitted off an aircraft, both in flight and on the ground, have been prepared based on estimates of data produced by on-board vehicle health sensors and initial concepts of data processing approaches. This allowed an initial estimate of VHM data transmission requirements for the airport surface. More recently, vehicle-level systems designed to process and analyze VHM data and draw conclusions on the current state of vehicle health have been undergoing testing and evaluation. These systems make use of vehicle system data that is mostly different from VHM data considered previously for airport surface transmission, and produce processed system outputs that will be also need to be archived, thus generating additional data load for AeroMACS. This paper provides an analysis of airport surface data transmission requirements resulting from the vehicle level reasoning systems, within the context of overall VHM data requirements.

  17. Defining Levels of Learning for Strengths Development Programs in Pharmacy

    OpenAIRE

    Kristin K. Janke, Ph.D.; Todd D. Sorensen, Pharm.D.; Andrew P. Traynor, Pharm.D., BCPS

    2010-01-01

    The Clifton StrengthsFinder® is an online measure of personal talent that identifies where an individual’s greatest potential for building strengths exists. This paper describes a framework for strengths education in pharmacy which includes introductory, intermediate and advanced levels of learning. The use of the StrengthsFinder® assessment and supporting workshops aids student pharmacists, pharmacy residents and practitioners in identifying and refining their talents and connecting talents ...

  18. Mac at Work

    CERN Document Server

    Sparks, David

    2011-01-01

    Bridge the gap between using a Mac at home and at the office. Now that you love your Mac at home, you want to use one at the office without missing a beat of productivity or professionalism. This unique guide shows you how.  You'll find best Mac business practices for handling word processing, spreadsheet and presentation creation, task and project management, and graphics. The book also explores topics such as hardware maintenance, how to synchronize with multiple computers, data backup, and communication with Windows networks.: Covers the nuts and bolts of using a Mac at work, including sync

  19. Wound healing in Mac-1 deficient mice.

    Science.gov (United States)

    Chen, Lin; Nagaraja, Sridevi; Zhou, Jian; Zhao, Yan; Fine, David; Mitrophanov, Alexander Y; Reifman, Jaques; DiPietro, Luisa A

    2017-05-01

    Mac-1 (CD11b/CD18) is a macrophage receptor that plays several critical roles in macrophage recruitment and activation. Because macrophages are essential for proper wound healing, the impact of Mac-1 deficiency on wound healing is of significant interest. Prior studies have shown that Mac-1(-/-) mice exhibit deficits in healing, including delayed wound closure in scalp and ear wounds. This study examined whether Mac-1 deficiency influences wound healing in small excisional and incisional skin wounds. Three millimeter diameter full thickness excisional wounds and incisional wounds were prepared on the dorsal skin of Mac-1 deficient (Mac-1(-/-) ) and wild type (WT) mice, and wound healing outcomes were examined. Mac-1 deficient mice exhibited a normal rate of wound closure, generally normal levels of total collagen, and nearly normal synthesis and distribution of collagens I and III. In incisional wounds, wound breaking strength was similar for Mac-1(-/-) and WT mice. Wounds of Mac-1 deficient mice displayed normal total macrophage content, although macrophage phenotype markers were skewed as compared to WT. Interestingly, amounts of TGF-β1 and its downstream signaling molecules, SMAD2 and SMAD3, were significantly decreased in the wounds of Mac-1 deficient mice compared to WT. The results suggest that Mac-1 deficiency has little impact on the healing of small excisional and incisional wounds. Moreover, the findings demonstrate that the effect of single genetic deficiencies on wound healing may markedly differ among wound models. These conclusions have implications for the interpretation of the many prior studies that utilize a single model system to examine wound healing outcomes in genetically deficient mice. © 2017 by the Wound Healing Society.

  20. CR-MAC: A multichannel MAC protocol for cognitive radio ad hoc networks

    CERN Document Server

    Kamruzzaman, S M

    2010-01-01

    This paper proposes a cross-layer based cognitive radio multichannel medium access control (MAC) protocol with TDMA, which integrate the spectrum sensing at physical (PHY) layer and the packet scheduling at MAC layer, for the ad hoc wireless networks. The IEEE 802.11 standard allows for the use of multiple channels available at the PHY layer, but its MAC protocol is designed only for a single channel. A single channel MAC protocol does not work well in a multichannel environment, because of the multichannel hidden terminal problem. Our proposed protocol enables secondary users (SUs) to utilize multiple channels by switching channels dynamically, thus increasing network throughput. In our proposed protocol, each SU is equipped with only one spectrum agile transceiver, but solves the multichannel hidden terminal problem using temporal synchronization. The proposed cognitive radio MAC (CR-MAC) protocol allows SUs to identify and use the unused frequency spectrum in a way that constrains the level of interference...

  1. Enterprise Mac Security Mac OS X Snow Leopard Security

    CERN Document Server

    Edge, Stephen Charles; Hunter, Beau; Sullivan, Gene; LeBlanc, Dee-Ann

    2010-01-01

    A common misconception in the Mac community is that Mac's operating system is more secure than others. While this might be true in certain cases, security on the Mac is still a crucial issue. When sharing is enabled or remote control applications are installed, Mac OS X faces a variety of security threats. Enterprise Mac Security: Mac OS X Snow Leopard is a definitive, expert-driven update of the popular, slash-dotted first edition and was written in part as a companion to the SANS Institute course for Mac OS X. It contains detailed Mac OS X security information, and walkthroughs on securing s

  2. Design of QoS-Aware Multi-Level MAC-Layer for Wireless Body Area Network.

    Science.gov (United States)

    Hu, Long; Zhang, Yin; Feng, Dakui; Hassan, Mohammad Mehedi; Alelaiwi, Abdulhameed; Alamri, Atif

    2015-12-01

    With the advances in wearable computing and various wireless technologies, there is an increasing trend to outsource body signals from wireless body area network (WBAN) to outside world including cyber space, healthcare big data clouds, etc. Since the environmental and physiological data collected by multimodal sensors have different importance, the provisioning of quality of service (QoS) for the sensory data in WBAN is a critical issue. This paper proposes multiple level-based QoS design at WBAN media access control layer in terms of user level, data level and time level. In the proposed QoS provisioning scheme, different users have different priorities, various sensory data collected by different sensor nodes have different importance, while data priority for the same sensor node varies over time. The experimental results show that the proposed multi-level based QoS provisioning solution in WBAN yields better performance for meeting QoS requirements of personalized healthcare applications while achieving energy saving.

  3. The MAC framework: redefining MAC protocols for wireless sensor networks

    NARCIS (Netherlands)

    Parker, T.; Halkes, G.; Bezemer, M.; Langendoen, K.

    2010-01-01

    Most current WSN MAC protocol implementations have multiple tasks to perform—deciding on correct timing, sending of packets, sending of acknowledgements, etc. However, as much of this is common to all MAC protocols, there is duplication of functionality, which leads to larger MAC protocol code size

  4. The MAC framework: redefining MAC protocols for wireless sensor networks

    NARCIS (Netherlands)

    Parker, T.; Halkes, G.; Bezemer, M.; Langendoen, K.

    2010-01-01

    Most current WSN MAC protocol implementations have multiple tasks to perform—deciding on correct timing, sending of packets, sending of acknowledgements, etc. However, as much of this is common to all MAC protocols, there is duplication of functionality, which leads to larger MAC protocol code size

  5. Recent results from MAC

    Energy Technology Data Exchange (ETDEWEB)

    MAC Collaboration

    1982-05-01

    Some preliminary results from the MAC detector at PEP are presented. These include measurements of the angular distribution of ..gamma gamma.., ..mu mu.. and tau tau final states, a determination of the tau lifetime, a measurement of R, and a presentation of the inclusive muon p/sub perpendicular/ distribution for hadronic events.

  6. Macs For Seniors For Dummies

    CERN Document Server

    Chambers, Mark L

    2012-01-01

    You're never too old to fall in love—with your Mac! You took a while, but you are now the proud owner of your first Mac computer. Macs For Seniors For Dummies is just for you. This friendly, accessible guide walks you through choosing a Mac and learning how to use it. You'll find yourself falling head over heels for your Mac in no time. Macs For Seniors For Dummies introduces you to all the basics that you need to know: turning the Mac on and getting connected; using the keyboard and mouse; working with files and folders; navigate around the Mac desktop and OS X Lion; setting up an Inter

  7. iMac pocket genius

    CERN Document Server

    Hart-Davis, Guy

    2010-01-01

    If you want to get the very most out of your iMac, put this savvy Portable Genius guide to work. Want to make the most of the new Magic Mouse and the latest iLife apps? Set up a wireless network using your iMac's AirPort card? Watch television on your iMac, or show iMac videos and movies on your television? You'll find cool and useful Genius tips, full-color screenshots, and pages of easy-to-access shortcuts and tools that will save you time and let you enjoy your iMac to the max.

  8. Monolithic MACS micro resonators

    Science.gov (United States)

    Lehmann-Horn, J. A.; Jacquinot, J.-F.; Ginefri, J. C.; Bonhomme, C.; Sakellariou, D.

    2016-10-01

    Magic Angle Coil Spinning (MACS) aids improving the intrinsically low NMR sensitivity of heterogeneous microscopic samples. We report on the design and testing of a new type of monolithic 2D MACS resonators to overcome known limitations of conventional micro coils. The resonators' conductors were printed on dielectric substrate and tuned without utilizing lumped element capacitors. Self-resonance conditions have been computed by a hybrid FEM-MoM technique. Preliminary results reported here indicate robust mechanical stability, reduced eddy currents heating and negligible susceptibility effects. The gain in B1 /√{ P } is in agreement with the NMR sensitivity enhancement according to the principle of reciprocity. A sensitivity enhancement larger than 3 has been achieved in a monolithic micro resonator inside a standard 4 mm rotor at 500 MHz. These 2D resonators could offer higher performance micro-detection and ease of use of heterogeneous microscopic substances such as biomedical samples, microscopic specimens and thin film materials.

  9. Blind Cognitive MAC Protocols

    CERN Document Server

    Mehanna, Omar; Gamal, Hesham El

    2008-01-01

    We consider the design of cognitive Medium Access Control (MAC) protocols enabling an unlicensed (secondary) transmitter-receiver pair to communicate over the idle periods of a set of licensed channels, i.e., the primary network. The objective is to maximize data throughput while maintaining the synchronization between secondary users and avoiding interference with licensed (primary) users. No statistical information about the primary traffic is assumed to be available a-priori to the secondary user. We investigate two distinct sensing scenarios. In the first, the secondary transmitter is capable of sensing all the primary channels, whereas it senses one channel only in the second scenario. In both cases, we propose MAC protocols that efficiently learn the statistics of the primary traffic online. Our simulation results demonstrate that the proposed blind protocols asymptotically achieve the throughput obtained when prior knowledge of primary traffic statistics is available.

  10. MacBook for dummies

    CERN Document Server

    Chambers , Mark L

    2014-01-01

    Make friends with your MacBook the fun and easy way! Ultra-light, ultra-fast, and ultra-powerful, the MacBook is the coolest laptop in town, and longtime Mac guru Mark L. Chambers is just the guy to help you get to know your MacBook in no time. Take a closer look at the latest features, get the lowdown on OS X, unleash your creative forces with iLife, take care of business with the iWork applications, and sync it all with iCloud with the expert advice in this bestselling MacBook guide. Whether this is your first MacBook or your first laptop, period, you''ll learn to navigate the Mac desktop, c

  11. Macs For Dummies, Pocket Edition

    CERN Document Server

    Baig, Edward C

    2011-01-01

    The fun and easy way to make the most of your wonderful Mac. Simply Mac-nificent — all the cool things your Mac can do! This handy guide helps you figure out the nuts and bolts of your Mac. Navigate the Mac desktop, use the Safari Web browser to surf the Internet, e-mail photos to friends and family, create and print documents, rip audio CDs, and more. The fun begins right here!. Open the book and find: How to set up and configure your Mac; Tips for getting around on the Mac desktop; Steps for setting up an e-mail account and browsing the Internet; Details about the free programs that come wit

  12. iMac portable genius

    CERN Document Server

    Hart-Davis, Guy

    2010-01-01

    The most up-to-date coverage on the latest iMac advice, tools, and shortcuts Cool and useful tips, full-color screenshots, and savvy advice show you how to get the most out of your iMac. Fully updated to cover the iMac's latest features and capabilities, this guide is packed with indispensible information on iLife '09 and Mac OS X Snow Leopard, and shows you how to customize your iMac in a way that it will work best for you.Explores all the bells and whistles of the iMac, including the new Magic Mouse, iLife apps such as iPhoto and iMovie, and Mac OS X Snow LeopardShows yo

  13. Quicksilver Power Mac G4

    CERN Multimedia

    2001-01-01

    A new generation with a reworked motherboard is launched on 2001 with however the same Graphite box. It also included a processor speed-bump, and brought the DVD-R "SuperDrive" to the mid-level model. The Quicksilver PowerMac was available in three configurations: The 733 MHz model, with 128 MB of RAM, a 40 GB hard drive, and a CD-RW drive, was 1,699 dollars, the 867 MHz configuration, with 128 MB of RAM, a 60 GB hard drive and a DVD-R drive, was 2,499 dollars, and the high-end dual-800 MHz model, with 256 MB of RAM, an 80 GB hard drive and a DVD-R drive, was 3,499 dollars. The 733 MHz model is the first personal computer to have a DVD burner, named SuperDrive at Apple. The design was updated on 2002 with 800 MHz, 933 MHz and dual 1 GHz configurations, becoming the first Mac to reach 1 GHz.

  14. CR-MAC: A Multichannel MAC Protocol for Cognitive Radio AD HOC Networks

    Directory of Open Access Journals (Sweden)

    S. M. Kamruzzaman

    2010-09-01

    Full Text Available This paper proposes a cross-layer based cognitive radio multichannel medium access control (MACprotocol with TDMA, which integrate the spectrum sensing at physical (PHY layer and the packetscheduling at MAC layer, for the ad hoc wireless networks. The IEEE 802.11 standard allows for the useof multiple channels available at the PHY layer, but its MAC protocol is designed only for a singlechannel. A single channel MAC protocol does not work well in a multichannel environment, because ofthe multichannel hidden terminal problem. Our proposed protocol enables secondary users (SUs toutilize multiple channels by switching channels dynamically, thus increasing network throughput. In ourproposed protocol, each SU is equipped with only one spectrum agile transceiver, but solves themultichannel hidden terminal problem using temporal synchronization. The proposed cognitive radioMAC (CR-MAC protocol allows SUs to identify and use the unused frequency spectrum in a way thatconstrains the level of interference to the primary users (PUs. Our scheme improves network throughputsignificantly, especially when the network is highly congested. The simulation results show that ourproposed CR-MAC protocol successfully exploits multiple channels and significantly improves networkperformance by using the licensed spectrum band opportunistically and protects PUs from interference,even in hidden terminal situations.

  15. iMac for dummies

    CERN Document Server

    Chambers, Mark L

    2014-01-01

    Do it all with your iMac and this bestselling For Dummies guide! You're still a little giddy from finally scoring your new iMac, and you can't wait to get started. Even if you're already in love with your iMac, it helps to have a little guidance to really get the most out of this ultimate all-in-one computer. This updated edition of iMac For Dummies is the ideal way to learn the iMac fundamentals from setting up and personalizing your machine to importing files, making FaceTime video calls, surfing the web, using your favorite programs and apps, and everything in between. Trusted Mac guru Mark

  16. Learn Excel 2011 for Mac

    CERN Document Server

    Hart-Davis, Guy

    2011-01-01

    Microsoft Excel 2011 for Mac OS X is a powerful application, but many of its most impressive features can be difficult to find. Learn Excel 2011 for Mac by Guy Hart-Davis is a practical, hands-on approach to learning all of the details of Excel 2011 in order to get work done efficiently on Mac OS X. From using formulas and functions to creating databases, from analyzing data to automating tasks, you'll learn everything you need to know to put this powerful application to use for a variety of tasks. What you'll learn * The secrets of the Excel for Mac interface! * How to create effective workbo

  17. Self Organizing Map of Artificial Neural Network for Defining Level of Service Criteria of Urban Streets

    Directory of Open Access Journals (Sweden)

    Smruti Sourava Mohapatra

    2012-09-01

    Full Text Available In India, Level of Service (LOS is not well defined for urban streets. The analysis procedure followed in India is that developed by HCM 2000. Speed ranges of LOS categories for various urban Street Classes defined by HCM are appropriate for developed countries having homogenous type of traffic flow. India being a developing country its traffic is very much heterogeneous having vehicles of different operational characteristics. Therefore, LOS criteria in Indian context should be defined correctly considering the traffic and geometric characteristics of urban streets. Defining LOS is basically a classification problem and application of cluster analysis is found to be a suitable technique to solve the problem. Self Organizing Map (SOM a type of Artificial Neural Network (ANN used to solve this classification problem. For this study, lot of speed data is required for which GPS is found to be the most suitable method of data collection and hence extensively used. Free flow speed (FFS and average travel speed during peak and off peak hours inventory of road segments are used in this study. FFS ranges for different urban Street Classes and speed ranges of LOS categories found to be lower than that mentioned in HCM-2000.

  18. Defining Top-of-Atmosphere Flux Reference Level for Earth Radiation Budget Studies

    Science.gov (United States)

    Loeb, N. G.; Kato, S.; Wielicki, B. A.

    2002-01-01

    To estimate the earth's radiation budget at the top of the atmosphere (TOA) from satellite-measured radiances, it is necessary to account for the finite geometry of the earth and recognize that the earth is a solid body surrounded by a translucent atmosphere of finite thickness that attenuates solar radiation differently at different heights. As a result, in order to account for all of the reflected solar and emitted thermal radiation from the planet by direct integration of satellite-measured radiances, the measurement viewing geometry must be defined at a reference level well above the earth s surface (e.g., 100 km). This ensures that all radiation contributions, including radiation escaping the planet along slant paths above the earth s tangent point, are accounted for. By using a field-of- view (FOV) reference level that is too low (such as the surface reference level), TOA fluxes for most scene types are systematically underestimated by 1-2 W/sq m. In addition, since TOA flux represents a flow of radiant energy per unit area, and varies with distance from the earth according to the inverse-square law, a reference level is also needed to define satellite-based TOA fluxes. From theoretical radiative transfer calculations using a model that accounts for spherical geometry, the optimal reference level for defining TOA fluxes in radiation budget studies for the earth is estimated to be approximately 20 km. At this reference level, there is no need to explicitly account for horizontal transmission of solar radiation through the atmosphere in the earth radiation budget calculation. In this context, therefore, the 20-km reference level corresponds to the effective radiative top of atmosphere for the planet. Although the optimal flux reference level depends slightly on scene type due to differences in effective transmission of solar radiation with cloud height, the difference in flux caused by neglecting the scene-type dependence is less than 0.1%. If an inappropriate

  19. Traffic-adaptive duty cycle adaptation in TR-MAC protocol for wireless sensor networks

    NARCIS (Netherlands)

    Morshed, Sarwar; Baratchi, Mitra; Heijenk, Geert

    2016-01-01

    The Medium Access Control (MAC) layer can influence the energy consumption of a wireless sensor network (WSN) to a significant level. TR-MAC is an energy-efficient preamble sampling based MAC protocol for low power WSNs suitable for low data rate and low duty cycle scenario. However, low data rate i

  20. DEFINING THE LEVELS OF COMPUTER GAME ADDICTION OF THE PRIMARY SCHOOL STUDENTS

    Directory of Open Access Journals (Sweden)

    Veysel Murat TUĞRUL

    2012-12-01

    Full Text Available This study aims to define the levels of computer game addiction of the 4th and 5th grade primary school students. The study used survey model. The study group was composed of 372 students from each age group. The data ofthe research were gathered by “Personal Infotmation Form” and “Computer Game Addication Scale”. Arithmetic mean, standard deviation, independent sampling t test, ANOVA and LSD tests were performed on collected data. The results showed that student scores of computer game eddition were low, but male students’ scores were higher than female ones. On the ather hand, someone had a computer at home, mothers’ education level were high were found to have higher score than others. There were no significant diffrence among classrooms and education level of fathers from the computer game addiction point of views.

  1. Model for defining the level of implementation of the management functions in small enterprises

    Directory of Open Access Journals (Sweden)

    Dragan Mišetić

    2001-01-01

    Full Text Available Small enterprises, based on private ownership and entrepreneurial capability, represent, for the majority of the scientific and professional public, the prime movers of economic growth, both in developed market economies and in the economies of countries in transition. At the same time, various studies show that the main reason for the bankruptcy of many small enterprises (more than 90% can be found in weak management, i.e. unacquaintance with management functions (planning, organization, human resources management, leading and control and with the need of implementing those functions in practice. Although it is not easy to define the ingredients of the recipe for success or to define precisely the importance of different elements, and regardless of the fact that many authors think that the management theory for large enterprises is inapplicable for the small ones, we all agree that the owner/manager and his implementation of the management theory has a decisive influence on small enterprises in modern economic circumstances. Therefore, the author of this work is hereby representing the model, which defines the level of implementation of management functions in small enterprises, as well as three systems/levels (danger, risk, progress in which small enterprises may find themselves. After the level of implementation of the management function is identified, it is possible to undertake some corrective actions, which will remove the found failures. While choosing the variables of the model, the author took into consideration specific features of a small enterprise, as well as specific features of its owner/manager.

  2. Ellen MacArthur

    Institute of Scientific and Technical Information of China (English)

    Teodora; Lazarova

    2006-01-01

    Just over a year since breaking the round theworld solo record on board her 75 foot trimaranB&O,Ellen MacArthur embarked on a newventure:the Asian Record Circuit 2006,incorpo-rating the ‘Tour Of China’,and bringing a differ-ent set of challenges into new territories.Wespoke to Ellen and her team during their recent(April)stopover in Oingdao.When did you start sailing and what inspiredyou(you grew up in Derbyshire,in the UK,quite far away from the water)?I was introduced to sailing by my Aunt Thea ona small sailing boat called Cabaret.We wentsailing along the east coast of EngLand andbefore I knew it,I was hooked on sailing.I wasso inspired that when I was at school,I saved

  3. Macs for seniors for dummies

    CERN Document Server

    Chambers, Mark L

    2009-01-01

    Over 50 and thinking about getting your first computer? A user-friendly Mac is a great choice, and Macs For Seniors For Dummies walks you through choosing one and learning to use it. You won't even need your grandchildren to help! Macs For Seniors For Dummies introduces you to all the basic things you may not have encountered before-how to use the keyboard and mouse, work with files and folders, navigate around the Mac OS X desktop, set up an Internet connection, and much more. You'll learn to:Choose the Mac that's right for you, set it up, run programs and manage files, and hook up a printerU

  4. iMac for dummies

    CERN Document Server

    Chambers, Mark L

    2012-01-01

    The bestselling guide to the ultimate all-in-one computer—now updated and revised throughout! If you're looking for speed, performance, and power, the iMac is the ultimate all-in-one computer. From its superior performance, powerful operating system, and amazing applications, the iMac is one awesome machine, and the fun, friendly, and approachable style of iMac For Dummies is an ideal way to get started with the basics. You'll learn the fundamentals of the iMac including setting up and customizing your iMac and the software that comes with it, importing files from your old computer, send

  5. Modeling MAC layer for powerline communications networks

    Science.gov (United States)

    Hrasnica, Halid; Haidine, Abdelfatteh

    2001-02-01

    The usage of electrical power distribution networks for voice and data transmission, called Powerline Communications, becomes nowadays more and more attractive, particularly in the telecommunication access area. The most important reasons for that are the deregulation of the telecommunication market and a fact that the access networks are still property of former monopolistic companies. In this work, first we analyze a PLC network and system structure as well as a disturbance scenario in powerline networks. After that, we define a logical structure of the powerline MAC layer and propose the reservation MAC protocols for the usage in the PLC network which provides collision free data transmission. This makes possible better network utilization and realization of QoS guarantees which can make PLC networks competitive to other access technologies.

  6. Una lectura interpretativa de Tras la virtud, de Alasdair MacIntyre - An Interpretive Reading of After Virtue, by Alasdair MacIntyre

    Directory of Open Access Journals (Sweden)

    Fernando Fernández-Llebrez

    2010-12-01

    Full Text Available This article centers on the thought of Alasdair MacIntyre, whose most prominente work, After Virtue, is considered a classic of political science. In contrast with other reviews, this article will examine After Virtue within the broader context of MacIntyre’s thinking and publications. An overview of MacIntyre’s literary corpus and the evolution of his thinking will shed light on the volume examined and trace certain ideas that are characteristic of this Scottish political philosopher. Matters that remained unsettled in After Virtue have become over time more defined in MacIntyre’s thinking, such as the influence exerted upon him by Thomas Aquinas.

  7. Gotcha! Macs lose their innocence

    CERN Multimedia

    Computer Security Team

    2012-01-01

    Still believe your Mac is secure because Microsoft PCs fall prey to viruses and worms but Macs don’t? Time to wake up! This year has seen the first major compromise of Macs worldwide*. How is yours doing?   The “Flashback” Trojan is affecting Apple’s own variant of Java and compromises Macs via so-called drive-by infections, i.e. when you visit an appropriately prepared (infected!) website - and this might not necessarily be a site with questionable contents, but could well be a popular, reputable one. Security Companies worldwide have been monitoring this particular Trojan for a while and have estimated that more than half a million Macs were compromised. Connected to a few central command and control servers, the compromised Macs were then supporting the malicious activity of the bad guys! Fortunately, the security companies have now been able to take over those command and control servers and stop their destructive drive. So, Mac users, face the f...

  8. Identification of entry-level competencies for associate degree radiographers as perceived by primary role definers

    Energy Technology Data Exchange (ETDEWEB)

    Thorpe, R.L.

    1981-01-01

    The primary purpose of this study was to identify those competencies needed by Associate Degree Radiographers when they assume employment as entry-level practitioners. A second purpose of the study was to rank order the identified competencies within the role delineations recognized by the Essentials and Guidelines of an Accredited Educational Program for the Radiographer. These role delineations include: radiation protection, exercise discretion and judgment, emergency and life saving techniques, patient care and interpersonal communication, and role as professional member. A third purpose of the study was to examine the degree of consensus on role definition of entry-level competencies needed by Associate Degree Radiographers as perceived by primary role definers (such as employers, employees, and educators), and by other selected variables: age, sex, length of experience in radiologic technology, level of formal education, and place of employment. A major finding of this study was that respondents did not differ significantly in their ranking of entry-level competencies needed by Associate Degree Radiographers when the responses were analyzed according to position, age, sex, length of experience, level of education, or place of employment. Another important finding was that respondents considered all of the 63 competencies as important and needed by Associate Degree Radiographers upon initial employment.A major conclusion and recommendation of this study, in view of the high agreement on the rank ordering of competencies, was that these competencies should be included in a competency-based education model. It was further recommended that a three-way system of communication between employers, employees, and educators be considered in order to pool resources and to increase understanding of each position group's contribution and influence on entry-level Associate Degree Radiographers.

  9. Relationship-Oriented Software Defined AS-Level Fast Rerouting for Multiple Link Failures

    Directory of Open Access Journals (Sweden)

    Chunxiu Li

    2015-01-01

    Full Text Available Large-scale deployments of mission-critical services have led to stringent demands on Internet routing, but frequently occurring network failures can dramatically degrade the network performance. However, Border Gateway Protocol (BGP can not react quickly to recover from them. Although extensive research has been conducted to deal with the problem, the multiple failure scenarios have never been properly addressed due to the limit of distributed control plane. In this paper, we propose a local fast reroute approach to effectively recover from multiple link failures in one administrative domain. The principle of Software Defined Networking (SDN is used to achieve the software defined AS-level fast rerouting. Considering AS relationships, efficient algorithms are proposed to automatically and dynamically find protection paths for multiple link failures; then OpenFlow forwarding rules are installed on routers to provide data forwarding continuity. Our approach is able to ensure applicability to ASes with flexibility and adaptability to multiple link failures, contributing toward improving the network performance. Through experimental results, we show that our proposal provides effective failure recovery and does not introduce significant control overhead to the network.

  10. Java and Mac OS X

    CERN Document Server

    Davis, T Gene

    2010-01-01

    Learn the guidelines of integrating Java with native Mac OS X applications with this Devloper Reference book. Java is used to create nearly every type of application that exists and is one of the most required skills of employers seeking computer programmers. Java code and its libraries can be integrated with Mac OS X features, and this book shows you how to do just that. You'll learn to write Java programs on OS X and you'll even discover how to integrate them with the Cocoa APIs.: Shows how Java programs can be integrated with any Mac OS X feature, such as NSView widgets or screen savers; Re

  11. Recommendations for Training in Pediatric Psychology: Defining Core Competencies Across Training Levels

    Science.gov (United States)

    Janicke, David M.; McQuaid, Elizabeth L.; Mullins, Larry L.; Robins, Paul M.; Wu, Yelena P.

    2014-01-01

    Objective As a field, pediatric psychology has focused considerable efforts on the education and training of students and practitioners. Alongside a broader movement toward competency attainment in professional psychology and within the health professions, the Society of Pediatric Psychology commissioned a Task Force to establish core competencies in pediatric psychology and address the need for contemporary training recommendations. Methods The Task Force adapted the framework proposed by the Competency Benchmarks Work Group on preparing psychologists for health service practice and defined competencies applicable across training levels ranging from initial practicum training to entry into the professional workforce in pediatric psychology. Results Competencies within 6 cluster areas, including science, professionalism, interpersonal, application, education, and systems, and 1 crosscutting cluster, crosscutting knowledge competencies in pediatric psychology, are presented in this report. Conclusions Recommendations for the use of, and the further refinement of, these suggested competencies are discussed. PMID:24719239

  12. MacRuby Ruby and Cocoa on OS X

    CERN Document Server

    Aimonetti, Matt

    2011-01-01

    Want to build native Mac OS X applications with a sleek, developer-friendly alternative to Objective-C? MacRuby is an ideal choice. This in-depth guide shows you how Apple's implementation of Ruby gives you access to all the features available to Objective-C programmers. You'll get clear, detailed explanations of MacRuby, including quick programming techniques such as prototyping. Perfect for programmers at any level, this book is packed with code samples and complete project examples. If you use Ruby, you can tap your skills to take advantage of Interface Builder, Cocoa libraries, the Objec

  13. Plasma Tissue Factor Pathway Inhibitor Levels in Angiographically Defined Coronary Artery Disease Among Saudis

    Directory of Open Access Journals (Sweden)

    Syed Shahid Habib

    2013-05-01

    Full Text Available Objectives: This study was aimed to determine plasma levels of total (TFPI-T and free (TFPI-F tissue factor pathway inhibitor, plasminogen activator inhibitor-1 (PAI-1, and tissue plasminogen activator (t-PA in a cohort of Saudi patients with chronic stable angiographically defined coronary artery disease (CAD and to determine its correlation with its severity.Methods: This cross sectional study was conducted in the department of physiology and department of cardiology, College of Medicine, and King Khalid University Hospital and King Saud University, Riyadh. Sixty known cases of CAD who had undergone angiography (35 males and 25 females were selected. A control group included 39 (20 males and 19 females healthy subjects. Fasting venous blood samples were analyzed for total (TFPI-T and free (TFPI-F tissue factor pathway inhibitor, plasminogen activator inhibitor-1 (PAI-1, and tissue plasminogen activator (t-PA. Gensini scores and vessel scores were determined for assessing CAD severity.Results: There were non-significant differences between age, body mass index (BMI and Blood pressure between the controls and CAD subjects. A comparison of hemostatic markers between control and CAD patients showed significantly higher levels of Fibrinogen, PAI-1, TFPI-T and TFPI-F in CAD patients compared to control subjects. But there was no difference in plasma t-PA levels. TFPI-T had a significant positive correlation with severity of disease determined by Gensini Scores (r=0.344; p=0.006 and vessel scores (r=0.338; p=0.015.Conclusion: Plasma levels of total tissue factor pathway inhibitor are significantly related with the presence and severity of CAD. Elevated levels of TFPI-T may be considered as useful diagnostic and prognostic markers in patients with CAD.

  14. Mac Programming for Absolute Beginners

    CERN Document Server

    Wang, Wallace

    2011-01-01

    Want to learn how to program on your Mac? Not sure where to begin? Best-selling author Wallace Wang will explain how to get started with Cocoa, Objective-C, and Xcode. Whether you are an experienced Windows coder moving to the Mac, or you are completely new to programming, you'll see how the basic design of a Mac OS X program works, how Objective-C differs from other languages you may have used, and how to use the Xcode development environment. Most importantly, you'll learn how to use elements of the Cocoa framework to create windows, store data, and respond to users in your own Mac programs.

  15. MacBook portable genius

    CERN Document Server

    Miser, Brad

    2008-01-01

    The Genius is in. You don't have to be a genius to use a MacBook. But if you want to get the very most out of yours, put this savvy Portable Genius guide to work. Want to connect your MacBook to other Macs? Use Expose to its fullest potential? Troubleshoot? You'll find cool and useful Genius tips, insider secrets, full-color screenshots, and pages of easy-to-access shortcuts and tools that will save you loads of time and make your MacBook IQ soar. Portable GENIUS Fun, hip, and straightforward, the new Portable Genius series gives forward-thinking Apple users useful informat

  16. Mac mini真体验

    Institute of Scientific and Technical Information of China (English)

    2010-01-01

    2005年,Mac mini首次登场,众所周知,苹果的模具更换的并不频繁,在外貌没有大幅改变的情况下,迄今为止,Mac mini实际上已经更新了7代。最新的Mac mini的工业设计实际上延续了2008年开始的Unibody一体成型铝合金机身设计与其他Mac在外观上保持了一致的元素。更小的Mac mini看起来更加性感诱人,那么,你需要它么?

  17. Relationship between current level of immunodeficiency and non-acquired immunodeficiency syndrome-defining malignancies

    DEFF Research Database (Denmark)

    Reekie, Joanne; Kosa, Csaba; Engsig, Frederik;

    2010-01-01

    In the combined antiretroviral therapy (cART) era, non-acquired immunodeficiency syndrome (AIDS)-defining malignancies account for more morbidity and mortality in human immunodeficiency virus-infected patients than AIDS-defining malignancies. However, conflicting data have been reported on the re......In the combined antiretroviral therapy (cART) era, non-acquired immunodeficiency syndrome (AIDS)-defining malignancies account for more morbidity and mortality in human immunodeficiency virus-infected patients than AIDS-defining malignancies. However, conflicting data have been reported...... on the relationship between immunodeficiency and the development of some non-AIDS-defining malignancies....

  18. Fiverr MacGyver

    Science.gov (United States)

    Hut, Rolf; van de Giesen, Nick; Larson, Martha

    2014-05-01

    Crowdsourcing has become popular over the past years, also for scientific endeavors. There are many Citizen Science projects and crowdfunding platforms, such as Kickstarter, that are make helpful contributions to moving environmental science forward. An interesting underused source of useful crowd-derived contributions to research is the website Fiverr.com. On this platform, thousands of people, acting as small-scale freelance contractors, offer their skills in the form of services. The platform offers a chance for people to take a hobby, skill, or pastime and make it something more by reaching out to a wider audience and by receiving a payment in return for services. As is typical of other crowdsourcing platforms, the tasks are small and usually self contained. As the name Fiverr suggests, offers start at US5 to provide a particular service. Services offered range from graphic design, to messages sung or spoken with various styles or accents, to complete apps for Android or iPhone. Skill providers on the platform can accept a range of variation of definition in the tasks, some can be described in general terms, for others it is more appropriate to provide examples. Fiverr provides a central location for those offering skills and those needing services to find each other, it makes it possible to communicate and exchange files, to make payments, and it provides support for resolving disputes. In all cases, it is important to keep expectations aligned with the nature of the platform: quality can and will vary. Ultimately, the critical contribution of Fiverr is not to replace professional services or otherwise save money, but rather to provide access to a large group of people with specialized skills who are able to make a contribution on short notice. In the context of this session, it can be considered a pool of people with MacGyver skills lying in wait of a MacGyyer task to attack. There are many ways in which Fiverr tasks, which are called 'gigs', can be useful in

  19. MacBook Teach Yourself VISUALLY

    CERN Document Server

    Miser, Brad

    2010-01-01

    Like the MacBook itself, Teach Yourself VISUALLY MacBook, Second Edition is designed to be visually appealing, while providing excellent functionality at the same time. By using this book, MacBook users will be empowered to do everyday tasks quickly and easily. From such basic steps as powering on or shutting down the MacBook, working on the Mac desktop with the Dashboard and its widgets to running Windows applications, Teach Yourself VISUALLY MacBook, Second Edition covers all the vital information and provides the help and support a reader needs—in many ways it's like having a Mac Genius at

  20. Switching to a Mac portable genius

    CERN Document Server

    McFedries, Paul

    2011-01-01

    Switching from a PC to a Mac is a breeze with this book Anyone considering making the move to Mac from the Windows world will find this book smoothes the way. While Macs are famous for ease of use, there are fundamental differences in Mac and PC ways of thinking, plus there?s the hassle of moving files, calendars, and other essential data from one platform to another. This guide lays out all the information, explains basic Mac procedures for the newcomer, offers great tips on data-sharing (including running Windows applications on a Mac), and provides everything the new Mac user needs to move

  1. Switching to a Mac For Dummies

    CERN Document Server

    Reinhold, Arnold

    2011-01-01

    Learn how to make the switch from PC to Mac a completely smooth transition The number of Mac users continues to increase significantly each year. If you are one of those people and are eager but also anxious about making the switch, then fear not! This friendly guide skips the jargon to deliver you an easy-to-read, understandable introduction to the Macintosh computer. Computer guru Arnold Reinhold walks you through the Mac OS, user interface, and icons. You'll learn how to set up your Mac, move your files from your PC to your Mac, switch applications, get your Mac online, network your Mac, se

  2. Recommendations for training in pediatric psychology: defining core competencies across training levels.

    Science.gov (United States)

    Palermo, Tonya M; Janicke, David M; McQuaid, Elizabeth L; Mullins, Larry L; Robins, Paul M; Wu, Yelena P

    2014-10-01

    As a field, pediatric psychology has focused considerable efforts on the education and training of students and practitioners. Alongside a broader movement toward competency attainment in professional psychology and within the health professions, the Society of Pediatric Psychology commissioned a Task Force to establish core competencies in pediatric psychology and address the need for contemporary training recommendations.   The Task Force adapted the framework proposed by the Competency Benchmarks Work Group on preparing psychologists for health service practice and defined competencies applicable across training levels ranging from initial practicum training to entry into the professional workforce in pediatric psychology.   Competencies within 6 cluster areas, including science, professionalism, interpersonal, application, education, and systems, and 1 crosscutting cluster, crosscutting knowledge competencies in pediatric psychology, are presented in this report.   Recommendations for the use of, and the further refinement of, these suggested competencies are discussed. © The Author 2014. Published by Oxford University Press on behalf of the Society of Pediatric Psychology. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

  3. Mac OS X Lion在Mac App Store上线

    Institute of Scientific and Technical Information of China (English)

    2011-01-01

    2011年7月20日,Apple宣布具有超过250种新功能的世界最先进操作系统的第八个重要版本Mac OS X Lion今天在Mac App StoreTM推出并可进行下载,价格为29.99美元。Lion的诸多超强功能包括:全新Multi-Touch手势;全系统支持全屏应用程序;

  4. Office 2011 for Mac For Dummies

    CERN Document Server

    LeVitus, Bob

    2011-01-01

    Get started with Office 2011 for Mac and discover the creative possibilitiesThe leading suite of productivity software for the Mac, Microsoft Office helps users complete common business tasks, including word processing, e-mail, presentations, financial analysis, and much more. Office 2011 for Mac For Dummies is the perfect companion for Microsoft Office for Mac users upgrading to the newest version, new computer users, and those who may have switched from the Windows version of Office. Written by one of the most popular gurus in the Mac community, Bob "Dr. Mac" LeVitus, the book explains every

  5. A Mac Protocol Implementation for Wireless Sensor Network

    Directory of Open Access Journals (Sweden)

    Jamila Bhar

    2015-01-01

    Full Text Available IEEE 802.15.4 is an important standard for Low Rate Wireless Personal Area Network (LRWPAN. The IEEE 802.15.4 presents a flexible MAC protocol that provides good efficiency for data transmission by adapting its parameters according to characteristics of different applications. In this research work, some restrictions of this standard are explained and an improvement of traffic efficiency by optimizing MAC layer is proposed. Implementation details for several blocks of communication system are carefully modeled. The protocol implementation is done using VHDL language. The analysis gives a full understanding of the behavior of the MAC protocol with regard to backoff delay, data loss probability, congestion probability, slot effectiveness, and traffic distribution for terminals. Two ideas are proposed and tested to improve efficiency of CSMA/CA mechanism for IEEE 802.15.4 MAC Layer. Primarily, we dynamically adjust the backoff exponent (BE according to queue level of each node. Secondly, we vary the number of consecutive clear channel assessment (CCA for packet transmission. We demonstrate also that slot compensation provided by the enhanced MAC protocol can greatly avoid unused slots. The results show the significant improvements expected by our approach among the IEEE 802.15.4 MAC standards. Synthesis results show also hardware performances of our proposed architecture.

  6. Rand and MacIntyre on moral agency

    OpenAIRE

    Beadle, Ron

    2008-01-01

    This paper contrasts the work of Ayn Rand and Alasdair MacIntyre on moral agency. Both argue that moral agency requires the application of a consistent moral code across relationships with others and that such consistency is rarely evident in the modern social order. However, while MacIntyre holds this failure to be a defining feature of the modern social order, Rand holds this to be a failure of individuals and a marker of a wider cultural confusion. While Rand sees selfishness and capitalis...

  7. 76 FR 12942 - Proposed Information Collection; Comment Request; Defining Target Levels for Ecosystem Components...

    Science.gov (United States)

    2011-03-09

    ... Target Levels for Ecosystem Components: A Socio-Ecological Approach AGENCY: National Oceanic and... numerous species, and a mean level of species placement within a predator/prey chain or food web can serve... statements regarding their perceptions of the health of the Puget Sound. Demographic and employment...

  8. An Empirical Study and some Improvements of the MiniMac Protocol for Secure Computation

    DEFF Research Database (Denmark)

    Damgård, Ivan Bjerre; Lauritsen, Rasmus; Toft, Tomas

    2014-01-01

    (nicknamed MiniMac). While TinyOT has already been implemented, we present in this paper the first implementation of MiniMac, using the same platform as the existing TinyOT implementation. We also suggest several improvements of MiniMac, both on the protocol design and implementation level. In particular, we...... suggest a modification of MiniMac that achieves increased parallelism at no extra communication cost. This gives an asymptotic improvement of the original protocol as well as an 8-fold speed-up of our implementation. We compare the resulting protocol to TinyOT for the case of secure computation in parallel...

  9. Geodetic leveling data used to define historical height changes between Tonopah Junction and Las Vegas, Nevada

    Energy Technology Data Exchange (ETDEWEB)

    Gilmore, T.D.

    1992-12-31

    This report documents geodetic leveling data for a survey route following US Highway 95 from Tonopah Junction, approximately 50 km west of Tonopah, Nevada, to Las Vegas, Nevada. The survey route passes immediately south of the potential site for a high-level nuclear waste repository at Yucca Mountain in southern Nevada. Comparisons among the results of the several repeated levelings along this survey route provide a partial basis for evaluating contemporary crustal deformation patterns in the vicinity of the Yucca Mountain site and the relation between any such deformation and geologic structures known or suspected to have been active during Quaternary time.

  10. Mac OS X Lion Server For Dummies

    CERN Document Server

    Rizzo, John

    2011-01-01

    The perfect guide to help administrators set up Apple's Mac OS X Lion Server With the overwhelming popularity of the iPhone and iPad, more Macs are appearing in corporate settings. The newest version of Mac Server is the ideal way to administer a Mac network. This friendly guide explains to both Windows and Mac administrators how to set up and configure the server, including services such as iCal Server, Podcast Producer, Wiki Server, Spotlight Server, iChat Server, File Sharing, Mail Services, and support for iPhone and iPad. It explains how to secure, administer, and troubleshoot the networ

  11. Take Control of Maintaining Your Mac

    CERN Document Server

    Kissell, Joe

    2009-01-01

    Keep your Mac running smoothly with our easy maintenance program! Regular maintenance is necessary to avoid problems and to ensure your Mac runs at peak performance, but it's hard to know what to do and when to do it. Best-selling author Joe Kissell has now applied his commonsense approach to the task of maintaining your Mac, whether you use Tiger or Leopard! Learn how to start on the right foot; what you should do daily, weekly, monthly, and yearly; and how to prepare for Mac OS X updates. Joe even explains how to monitor your Mac's health and debunks common panaceas. Read this book to lea

  12. Switching to a Mac For Dummies

    CERN Document Server

    Reinhold, Arnold

    2007-01-01

    Thinking of making the switch from your PC to a Mac? Congratulations! You're in for a great, virus-free ride. And Switching to Mac For Dummies makes it smoother than you ever imagined. From buying the Mac that's right for you to transferring your files to breaking your old Windows habits and learning to do things the (much easier) Mac way, it makes the whole process practically effortless. Whether you've been using Windows XP, Vista, or even Linux, you'll find simple, straightforward ways to make your transition go smoothly. That will leave you plenty of time to get familiar with Mac'

  13. Switching to the Mac The Missing Manual

    CERN Document Server

    Pogue, David

    2010-01-01

    Is Windows giving you pause? Ready to make the leap to the Mac instead? There has never been a better time to switch from Windows to Mac, and this incomparable guide will help you make a smooth transition. New York Times columnist and Missing Manuals creator David Pogue gets you past three challenges: transferring your stuff, assembling Mac programs so you can do what you did with Windows, and learning your way around Mac OS X. Learning to use a Mac is not a piece of cake, but once you do, the rewards are oh-so-much better. No viruses, worms, or spyware. No questionable firewalls, inefficien

  14. Cognitive MAC designs for OSA networks

    CERN Document Server

    Derakhshani, Mahsa

    2014-01-01

    This SpringerBrief presents recent advances in the cognitive MAC designs for opportunistic spectrum access (OSA) networks. It covers the basic MAC functionalities and MAC enhancements of IEEE 802.11. Later chapters discuss the existing MAC protocols for OSA and classify them based on characteristic features. The authors provide new research in adaptive carrier sensing-based MAC designs tailored for OSA, which optimize spectrum utilization and ensure a peaceful coexistence of licensed and unlicensed systems. Analytically devised via optimization and game-theoretic approaches, these adaptive M

  15. Growth of Mycobacterium tuberculosis in a Defined Medium Is Very Restricted by Acid pH and Mg2+ Levels

    OpenAIRE

    Piddington, Debra L.; Kashkouli, Ali; Buchmeier, Nancy A.

    2000-01-01

    Mycobacterium tuberculosis grows within the phagocytic vacuoles of macrophages, where it encounters a moderately acidic and possibly nutrient-restricted environment. Other mycobacterial species encounter acidic conditions in soil and aquatic environments. We have evaluated the influence of pH and divalent cation levels on the growth of M. tuberculosis and seven other mycobacterial species. In a defined medium, the growth of M. tuberculosis was very restricted by acidic pH. Higher levels of Mg...

  16. A farm level approach to define successful mitigation strategies for GHG emissions from ruminant livestock systems

    NARCIS (Netherlands)

    Schils, R.L.M.; Verhagen, A.; Aarts, H.F.M.; Sebek, L.B.J.

    2005-01-01

    Ruminant livestock systems are a significant source of greenhouse gases (GHGs). Thus far, mitigation options for GHG emissions mainly focused on a single gas, and are treated as isolated activities. The present paper proposes a framework for a farm level approach for the full accounting of GHG

  17. Sevoflurane decreases bispectral index values more than does halothane at equal MAC multiples.

    Science.gov (United States)

    Schwab, Hildebrand S; Seeberger, Manfred D; Eger, Edmond I; Kindler, Christoph H; Filipovic, Miodrag

    2004-12-01

    At the minimum alveolar concentration (MAC) of inhaled anesthetics, 50% of subjects move in response to noxious stimulation. Similarly, at MAC-awake, 50% of subjects respond appropriately to command. The bispectral index (BIS) nominally measures the effect of anesthetics on wakefulness or consciousness. We postulated that the use of halothane with a larger MAC-awake/MAC ratio than sevoflurane would produce higher BIS values at comparable levels of MAC. We studied 33 unpremedicated patients anesthetized by inhalation, 18 with sevoflurane and 15 with halothane. We measured BIS before and during anesthesia at 1 MAC, both before and after tracheal intubation facilitated by fentanyl and rocuronium and then at 1.5 MAC. BIS measurements were made after meeting steady-state conditions. No surgery was performed during this study. BIS values in awake patients did not differ between the sevoflurane and halothane groups (96 +/- 2 and 96 +/- 2, mean +/- sd, respectively). At 1 MAC without and with neuromuscular blockade and at 1.5 MAC, BIS values for patients anesthetized with halothane (54 +/- 7, 56 +/- 7, and 49 +/- 7, respectively) exceeded those for patients anesthetized with sevoflurane (34 +/- 6, 34 +/- 6, and 29 +/- 5, respectively) (P < 0.0001). This finding adds to other evidence indicating that BIS is drug specific.

  18. A Fair-Priority MAC design in Networked Control System

    Directory of Open Access Journals (Sweden)

    Hongjun Li

    2009-10-01

    Full Text Available Media Access Control (MAC protocols in Wireless Networked Control System (WNCS must minimize the radio energy costs in sensor nodes. Latency and throughput are also important design features for MAC protocols in the applications. But most of them cannot guarantee quality for real-time traffic. This paper studies the state of the art of current real-time MAC protocols, and then introduces a medium access control protocol and a improved protocol that provide multiple priority levels and hard real-time transmission. The channel is accessed by sensors according to their priorities. Sensors send frames in a round manner with same priority. The fairness between different priorities is provided. The channel access procedure is divided into two stages: broadcast period and transmission period. Simulation and experiment results indicate that our protocol provides high channel utilization and bounded delays for real-time communication and can be well applied in the many fields especially the dynamic wireless sensor networks.

  19. ETEEM- Extended Traffic Aware Energy Efficient MAC Scheme for WSNs

    Directory of Open Access Journals (Sweden)

    Younas Khan

    2016-11-01

    Full Text Available Idle listening issue arises when a sensor node listens to medium despite the absence of data which results in consumption of energy. ETEEM is a variant of Traffic Aware Energy Efficient MAC protocol (TEEM which focuses on energy optimization due to reduced idle listening time and much lesser overhead on energy sources. It uses a novel scheme for using idle listening time of sensor nodes. The nodes are only active for small amount of time and most of the time, will be in sleep mode when no data is available. ETEEM reduces energy at byte level and uses a smaller byte packet called FLAG replacing longer byte SYNC packets of S-MAC and SYNCrts of TEEM respectively. It also uses a single acknowledgement packet per data set hence reducing energy while reducing frequency of the acknowledgment frames sent. The performance of ETEEM is 70% better comparative to other under-consideration MAC protocols.

  20. Link-layer jamming attacks on S-MAC

    OpenAIRE

    Law, Yee Wei; Hartel, Pieter; Hartog, den, D.N.; Havinga, Paul

    2005-01-01

    We argue that among denial-of-service (DoS) attacks, link-layer jamming is a more attractive option to attackers than radio jamming is. By exploiting the semantics of the link-layer protocol (aka MAC protocol), an attacker can achieve better efficiency than blindly jamming the radio signals alone. In this paper, we investigate some jamming attacks on S-MAC, the level of effectiveness and efficiency the attacks can potentially achieve, and a countermeasure that can be implemented against one o...

  1. Defining obesity: second-level agenda setting attributes in black newspapers and general audience newspapers.

    Science.gov (United States)

    Lee, Hyunmin; Len-Ríos, María E

    2014-01-01

    This content analysis study examines how obesity is depicted in general-audience and Black newspaper stories (N=391) through the lens of second-level agenda setting theory. The results reveal that both Black newspapers and general-audience newspapers generally ascribe individual causes for obesity. While both types of newspapers largely neglected to mention solutions for the problem, Black newspapers were more likely than general-audience newspapers to suggest both individual and societal solutions for treating obesity. For Black newspapers, these solutions more often included community interventions. In addition, Black newspapers more often used a negative tone in stories and more frequently mentioned ethnic and racial minorities as at-risk groups.

  2. Sevoflurane at 1 MAC provides optimal myocardial protection during off-pump CABG.

    Science.gov (United States)

    Wang, Jiang; Zheng, Hong; Chen, Chun-Ling; Lu, Wei; Zhang, Yong-Qiang

    2013-06-01

    We investigated the myocardial protective effect of sevoflurane in patients receiving off-pump coronary artery bypass grafting (OPCABG) and the role of brain natriuretic peptide (BNP). Forty-eight patients receiving elective OPCABG were randomly assigned to a control group, and to 0.75 MAC, 1.0 MAC and 1.5 MAC sevoflurane groups. Blood samples were collected and levels of BNP and cardiac troponin I (cTnI) were measured before anesthesia, and immediately, 24, 48 and 72 h after surgery. Dopamine was necessary to maintain blood pressure in the sevoflurane groups, but not in the control group (p MAC sevoflurane significantly decreased post-surgical cTnI levels (p MAC had no significant effect, and increasing sevoflurane concentrations to 1.5 MAC caused no further decrease in cTnI concentrations. There was no significant difference in BNP level among the groups (p = 0.227) or between any two groups, although values of BNP showed a significant correlation with cTnI values in control subjects immediately after (r = 0.847) and 24 h after (r = 0.661) surgery. Our results demonstrated that 1.0 MAC and 1.5 MAC sevoflurane can exert a significant myocardial protective effect. BNP cannot be used to predict the myocardial protective effect of sevoflurane in OPCABG.

  3. Use of the channel fill level in defining a design space for twin screw wet granulation.

    Science.gov (United States)

    Gorringe, L J; Kee, G S; Saleh, M F; Fa, N H; Elkes, R G

    2017-03-15

    Twin screw wet granulation is a key process in the continuous manufacture of oral solid dosage forms. Previous research has qualitatively suggested that the channel fill level influences the granules produced. In this paper a quantitative measure of the total volumetric fraction of the conveying element channels of the screw filled with powder (φ) was used. Experimental results are shown which demonstrate that very similar particle size distributions can be obtained at the same φ with the same material and screw configuration but radically different solids feed rates and screw speeds. Morphology of the granules also correlates with φ. This is consistent with previous observations in the literature correlating granule attributes with powder feed rate and screw speed but also considers the two parameters in combination. A process design space approach based on φ is proposed. This can be determined empirically, and potentially has value in setting process control strategies, assuring process robustness and allowing process flexibility during the product lifecycle. Copyright © 2017 Elsevier B.V. All rights reserved.

  4. Fluorescent biosensors illuminate calcium levels within defined beta-cell endosome subpopulations.

    Science.gov (United States)

    Albrecht, Tobias; Zhao, Yongxin; Nguyen, Trang Hai; Campbell, Robert E; Johnson, James D

    2015-04-01

    Live cell imaging has revealed that calcium ions (Ca(2+)) pass in and out of many cellular organelles. However, technical hurdles have limited measurements of Ca(2+) in acidic organelles, such as endosomes. Although evidence hints that endosomes play a role in Ca(2+) signaling, direct measurements within endosomal lumina represent one of the final frontiers in organelle imaging. To measure Ca(2+) in a TiVAMP-positive endosome sub-population, the pH-resistant ratiometric Ca(2+) biosensor GEM-GECO1 and the ratiometric pH biosensor mKeima were used. A positive correlation between acidic endosomal pH and higher Ca(2+) was observed within these Rab5a- and Rab7-positive compartments. Ca(2+) concentration in most endosomes was estimated to be below 2μM, lower than Ca(2+) levels in several other intracellular stores, indicating that endosomes may take up Ca(2+) during physiological stimulation. Indeed, endosomes accumulated Ca(2+) during glucose-stimulation, a condition where endosomal pH did not change. Our biosensors permitted the first measurements revealing a role for endosomes in cellular Ca(2+) homeostasis during physiological stimulation.

  5. Level of FACT defines the transcriptional landscape and aggressive phenotype of breast cancer cells.

    Science.gov (United States)

    Fleyshman, Daria; Prendergast, Laura; Safina, Alfiya; Paszkiewicz, Geraldine; Commane, Mairead; Morgan, Kelsey; Attwood, Kristopher; Gurova, Katerina

    2017-03-28

    Although breast cancer (BrCa) may be detected at an early stage, there is a shortage of markers that predict tumor aggressiveness and a lack of targeted therapies. Histone chaperone FACT, expressed in a limited number of normal cells, is overexpressed in different types of cancer, including BrCa. Recently, we found that FACT expression in BrCa correlates with markers of aggressive BrCa, which prompted us to explore the consequences of FACT inhibition in BrCa cells with varying levels of FACT.FACT inhibition using a small molecule or shRNA caused reduced growth and viability of all BrCa cells tested. Phenotypic changes were more severe in "high- FACT" cells (death or growth arrest) than in "low-FACT" cells (decreased proliferation). Though inhibition had no effect on the rate of general transcription, expression of individual genes was changed in a cell-specific manner. Initially distinct transcriptional profiles of BrCa cells became similar upon equalizing FACT expression. In "high-FACT" cells, FACT supports expression of genes involved in the regulation of cell cycle, DNA replication, maintenance of an undifferentiated cell state and regulated by the activity of several proto-oncogenes. In "low-FACT" cells, the presence of FACT reduces expression of genes encoding enzymes of steroid metabolism that are characteristic of differentiated mammary epithelia.Thus, we propose that FACT is both a marker and a target of aggressive BrCa cells, whose inhibition results in the death of BrCa or convertion of them to a less aggressive subtype.

  6. Mac OS X Tiger for Unix Geeks

    CERN Document Server

    Jepson, Brian

    2005-01-01

    If you're one of the many Unix developers drawn to Mac OS X for its Unix core, you'll find yourself in surprisingly unfamiliar territory. Unix and Mac OS X are kissing cousins, but there are enough pitfalls and minefields in going from one to another that even a Unix guru can stumble, and most guides to Mac OS X are written for Mac aficionados. For a Unix developer, approaching Tiger from the Mac side is a bit like learning Russian by reading the Russian side of a Russian-English dictionary. Fortunately, O'Reilly has been the Unix authority for over 25 years, and in Mac OS X Tiger for Unix Gee

  7. Gravitational Duality in MacDowell-Mansouri Gauge Theory

    CERN Document Server

    García-Compéan, H; Ramírez, C

    1998-01-01

    Strong-weak duality invariance can only be defined for particular sectors of supersymmetric Yang-Mills theories. Nevertheless, for full non-Abelian non-supersymmetric theories, dual theories with inverted couplings, have been found. We show that an analogous procedure allows to find the dual action to the gauge theory of gravity constructed by the MacDowell-Mansouri model plus the superposition of a $\\Theta$ term.

  8. Teach yourself visually Mac Mini

    CERN Document Server

    Hart-Davis, Guy

    2012-01-01

    The perfect how-to guide for visual learners Apple?s Mac Mini packs a powerful punch is in a small package, including both HDMI and Thunderbolt ports plus the acclaimed OS X. But if you want to get the very most from all this power and versatility, be sure to get this practical visual guide. With full-color, step-by-step instructions as well as screenshots and illustrations on every page, it clearly shows you how to accomplish tasks rather than burying you in pages of text. Discover helpful visuals and how-tos on the OS, hardware specs, Launchpad, the App Store, multimedia capabilities (such

  9. Web Development with the Mac

    CERN Document Server

    Vegh, Aaron

    2010-01-01

    Learn Web development the Apple way and build a business. With a focus on both coding and creative development, this in-depth guide thoroughly covers what you need to know to build winning websites for clients — from what it takes to bring a business online to how to make your site interactive to how to run a freelance web business. In between, you'll master the technical tools of the trade — such as HTML, CSS, JavaScript, PHP, and Ruby on Rails — and learn how to create beautiful interfaces using Photoshop . This book covers everything a fledgling web developer working on a Mac needs to launc

  10. A Comparison Between Two Methods of Face-Lift Surgery in Nine Cadavers: SMAS (Superficial Musculo-Aponeurotic System) Versus MACS (Minimal Access Cranial Suspension).

    Science.gov (United States)

    Mohammadi, Shabahang; Ahmadi, Aslan; Salem, Mohammad Mahdi; Safdarian, Mahdi; Ilkhani, Shahriar

    2015-10-01

    This study aimed to compare the average amounts of facial skin and muscle lifting in two different face-lift methods, superficial musculo-aponeurotic system (SMAS) plication and minimal access cranial suspension (MACS), to evaluate the effectiveness of each method in facial excursion. Thirty-six face-lift surgeries were performed on nine cadavers between October and December 2010. Both SMAS and MACS surgeries were done on each side of the cadaver faces. The average amounts of skin and muscle lifting up and out in three defined anatomical landmarks were compared between the two methods, SMAS plication and MACS lift procedure. Nine fresh cadavers with the mean age of 53 ± 6.7 years entered the study. Seven (77.8 %) were males and two (22.2 %) were females. The average amounts of lifting of the anatomical landmarks up and out were significantly greater in the SMAS plication method compared to the MACS lift procedure (P values <0.05), whereas facial symmetry was not significantly different between the two methods. The overall amounts of facial skin and muscle lifting by the SMAS plication method were greater than the MACS lift procedure. However, it does not justify ignoring the benefits of the MACS lift procedure in terms of less invasiveness and quicker recovery. This journal requires that authors assign a level of evidence to each submission to which Evidence-Based Medicine rankings are applicable. For a full description of these Evidence-Based Medicine ratings, please refer to the Table of Contents or the online Instructions to Authors www.springer.com/00266 .

  11. Analysis of 3gpp-MAC and two-key 3gpp-MAC

    DEFF Research Database (Denmark)

    Knudsen, Lars Ramkilde; Mitchell, C.J.

    2003-01-01

    Forgery and key-recovery attacks are described on the 3gpp-MAC scheme, proposed for inclusion in the 3gpp specification. Three main classes of attack are given, all of which operate whether or not truncation is applied to the MAC value. Attacks in the first class use a large number of 'chosen MACs......', those in the second class use a large number of 'known MACs', and those in the third class require a large number of MAC verifications, but very few known MACS and no chosen MACS. The first class yields both forgery and key-recovery attacks, whereas the second and third classes are key-recovery attacks...... only. Both single-key and two-key variants of 3gpp-MAC are considered; the forgery attacks are relevant to both variants, whereas the key-recovery attacks are only relevant to the two-key variant....

  12. Analysis of 3gpp-MAC and two-key 3gpp-MAC

    DEFF Research Database (Denmark)

    Knudsen, Lars Ramkilde; Mitchell, C.J.

    2003-01-01

    Forgery and key-recovery attacks are described on the 3gpp-MAC scheme, proposed for inclusion in the 3gpp specification. Three main classes of attack are given, all of which operate whether or not truncation is applied to the MAC value. Attacks in the first class use a large number of 'chosen MACs......', those in the second class use a large number of 'known MACs', and those in the third class require a large number of MAC verifications, but very few known MACS and no chosen MACS. The first class yields both forgery and key-recovery attacks, whereas the second and third classes are key-recovery attacks...... only. Both single-key and two-key variants of 3gpp-MAC are considered; the forgery attacks are relevant to both variants, whereas the key-recovery attacks are only relevant to the two-key variant....

  13. Mac protocols for cyber-physical systems

    CERN Document Server

    Xia, Feng

    2015-01-01

    This book provides a literature review of various wireless MAC protocols and techniques for achieving real-time and reliable communications in the context of cyber-physical systems (CPS). The evaluation analysis of IEEE 802.15.4 for CPS therein will give insights into configuration and optimization of critical design parameters of MAC protocols. In addition, this book also presents the design and evaluation of an adaptive MAC protocol for medical CPS, which exemplifies how to facilitate real-time and reliable communications in CPS by exploiting IEEE 802.15.4 based MAC protocols. This book wil

  14. Take control of troubleshooting your Mac

    CERN Document Server

    Kissell, Joe

    2009-01-01

    Learn how to solve any Mac problem with Joe Kissell's expert advice! We may love our Macs, but they can still suffer significant problems. In this essential guide from best-selling author Joe Kissell, you'll learn 17 basic troubleshooting procedures and how to solve 9 common problems, along with an easy-to-follow way to troubleshoot novel problems. Whether your Mac won't turn on, experiences kernel panics repeatedly, or is glacially slow, this book has the calm, friendly advice you need to find a solution. Following in the footsteps of his critically acclaimed books Take Control of Mac OS X

  15. Teach yourself visually MacBook Pro

    CERN Document Server

    Hart-Davis, Guy

    2014-01-01

    Clear instructions to help visual learners get started with their MacBook Pro Covering all the essential information you need to get up to speed with your MacBook Pro, this new edition provides you with the most up-to-date information on performing everyday tasks quickly and easily. From basics such as powering on or shutting down the MacBook Pro to more advanced tasks such as running Windows applications, this visual guide provides the help and support you need to confidently use your MacBook Pro to its full potential.Empowers you to perform everyday tasks quickly and easilyCovers new hardwa

  16. Take control the Mac OS X lexicon

    CERN Document Server

    Zardetto, Sharon

    2009-01-01

    This ebook explains a little bit of everything; in fact, it's The Mac OS X (and then some) Lexicon because it's never just you and your Mac. It's you and your Mac and the Web, and your email, and that article you just read that threw 17 new acronyms at you or assumed that you knew all sorts of networking terms. Or it's you and your Mac and Finder features you've never touched, such as burn folders, smart folders, or proxy icons, and that mysterious Services submenu. This book is a great guide for Macintosh users everywhere who have trouble keeping up with the latest jargon, fo

  17. Macs all-in-one for dummies

    CERN Document Server

    Hutsko, Joe

    2014-01-01

    Your all-in-one guide to unleashing your Mac's full potential It's a Mac world out there. But if you haven't read the instruction manual, you may be neglecting some of your computer's coolest features. Turn to Macs All-in-One For Dummies' jam-packed guide to access the incredible tools within your computer. With this fully updated reference, you will learn how to use Launchpad and Mission Control; protect your Mac; back up and restore data with Time Machine; sync across devices in iCloud; import, organize, and share photos; direct in iMovie; compose in GarageBand; and so much more. The possi

  18. Defining Quality of Life Levels to Enhance Clinical Interpretation in Multiple Sclerosis: Application of a Novel Clustering Method.

    Science.gov (United States)

    Michel, Pierre; Baumstarck, Karine; Boyer, Laurent; Fernandez, Oscar; Flachenecker, Peter; Pelletier, Jean; Loundou, Anderson; Ghattas, Badih; Auquier, Pascal

    2017-01-01

    To enhance the use of quality of life (QoL) measures in clinical practice, it is pertinent to help clinicians interpret QoL scores. The aim of this study was to define clusters of QoL levels from a specific questionnaire (MusiQoL) for multiple sclerosis (MS) patients using a new method of interpretable clustering based on unsupervised binary trees and to test the validity regarding clinical and functional outcomes. In this international, multicenter, cross-sectional study, patients with MS were classified using a hierarchical top-down method of Clustering using Unsupervised Binary Trees. The clustering tree was built using the 9 dimension scores of the MusiQoL in 2 stages, growing and tree reduction (pruning and joining). A 3-group structure was considered, as follows: "high," "moderate," and "low" QoL levels. Clinical and QoL data were compared between the 3 clusters. A total of 1361 patients were analyzed: 87 were classified with "low," 1173 with "moderate," and 101 with "high" QoL levels. The clustering showed satisfactory properties, including repeatability (using bootstrap) and discriminancy (using factor analysis). The 3 clusters consistently differentiated patients based on sociodemographic and clinical characteristics, and the QoL scores were assessed using a generic questionnaire, ensuring the clinical validity of the clustering. The study suggests that Clustering using Unsupervised Binary Trees is an original, innovative, and relevant classification method to define clusters of QoL levels in MS patients.

  19. MAQF/MAC:A New QoS Provisioning MAC Mechanism for MANET

    Institute of Scientific and Technical Information of China (English)

    YAOYinxion; WANGHaoxing; WANXiang

    2003-01-01

    QoS provisioning is not an easy problem under the time varying and dynamic environment of MANET.Based on MANET Adaptive QoS Framework(MAQF)and through improving the scheme of MACA/PR,a new mechanism MAQF/MAC that can provide MAC layer QoS guarantees for MANET has been presented.MAQF/MAC can measure the variation of resource in real time,change the channel access policy and adapt the amount of resource captured by trafflc.In addition,this paper also concerns some key components of MAQF/MAC,including reservation table(RT),QoS routing,resource compression algorithm and etc.Simulation result show that MAQF/MAC ls superior to MACA/PR in the aspects of multi-level trafflc QoS provisioning and resource utilization.

  20. A MAC Mode for Lightweight Block Ciphers

    DEFF Research Database (Denmark)

    Luykx, Atul; Preneel, Bart; Tischhauser, Elmar Wolfgang;

    2016-01-01

    , but also allows high-performance parallel implementations. We highlight this in a comprehensive implementation study, instantiating LightMAC with PRESENT and the AES. Moreover, LightMAC allows flexible trade-offs between rate and maximum message length. Unlike PMAC and its many derivatives, Light...

  1. MAC-awake of sevoflurane in children.

    Science.gov (United States)

    Davidson, Andrew J; Wong, Aaron; Knottenbelt, Graham; Sheppard, Suzette; Donath, Susan; Frawley, Geoff

    2008-08-01

    Age influences the potency of anesthetic agents, but there is little information on how age influences MAC-awake. MAC-awake may be an important aspect of anesthesia potency for the prevention of awareness during anesthesia. The aim of this study was to measure MAC-awake in a range of ages in children. After institutional ethics approval and informed parental consent 60 children were enrolled; 20 in each of three age groups (2 to awake. The Dixon up-down method was used to determine progression of subsequent concentrations and MAC-awake (ED50) for the three age groups were obtained using the probit model. This study found evidence for a difference in ED50 between age groups (P = 0.008). The MAC-awake was highest in the youngest group (0.66%) and similar in the older groups (0.45% and 0.43%). Although MAC-awake changes with age, in the ages where awareness has been reported, MAC-awake was found to be relatively low, and therefore it seems unlikely that age-specific changes to MAC-awake are a cause for awareness in children aged 5-12 years.

  2. Nomogram to estimate age-related MAC.

    NARCIS (Netherlands)

    Lerou, J.G.C.

    2004-01-01

    BACKGROUND: In clinical practice it is difficult to estimate rapidly two important values: (i) the total age-corrected MAC multiple from measured end-expired concentrations of volatile agent and nitrous oxide; (ii) the end-expired concentration of volatile agent needed to obtain a given total MAC

  3. VLA-MAC: A Variable Load Adaptive MAC Protocol for Wireless Sensor Networks

    Science.gov (United States)

    Yao, Guoliang; Liu, Hao; Chen, Hao; Shi, Longxin

    This letter presents VLA-MAC, a novel adaptive MAC protocol for wireless sensor networks that can achieve high energy efficiency and low latency in variable load conditions. In VLA-MAC, traffic load is measured online and utilized for adaptive adjustment. VLA-MAC transmits packets via a burst style to alleviate packets accumulation problem and achieve low latency in high load condition. Furthermore, it also saves obvious energy by removing unnecessary listen period in low load condition. Unlike current approach, VLA-MAC does not need to adjust duty-cycle according to load online. Simulation results based on ns-2 show the performance improvements of our protocol.

  4. Investigation of Serum Oxidized Low-Density Lipoprotein IgG Levels in Patients with Angiographically Defined Coronary Artery Disease

    Directory of Open Access Journals (Sweden)

    Mohsen Moohebati

    2014-01-01

    Full Text Available It has been suggested that antioxidized low-density lipoprotein (anti-oxLDL antibodies play a role in the pathogenesis of atherosclerosis. The aim of this study was to measure serum ox-LDL IgG levels in 31 patients with angiographically defined coronary artery disease (CAD (≥50% stenosis in at least one major coronary artery; CAD+ group and compare these levels with those of 32 subjects with <50% coronary stenosis (CAD− group and 24 healthy age- and sex-matched controls using ELISA. We did not find any significant difference between CAD+, CAD−, and control groups in regard to oxLDL IgG levels (P=0.83. Serum oxLDL IgG levels did not differ between 1VD (one vessel disease, 2VD (2 vessels disease, and 3VD (3 vessels disease subgroups of CAD+ patients (P=0.20. Serum anti-oxLDL titers were only significantly correlated with LDL-C in the CAD+ group (P<0.05 and waist and hip circumference (P<0.05 and P<0.01, resp. in the CAD− group. In stepwise regression analysis, none of the conventional cardiovascular risk factors was associated with serum ox-LDL IgG levels. The present results suggest that serum levels of ox-LDL IgG are neither associated with the presence and severity of CAD nor with the conventional cardiovascular risk factors.

  5. Mac OS X Snow Leopard for dummies

    CERN Document Server

    LeVitus, Bob

    2010-01-01

    Get to know Snow Leopard and make the most of your Mac Snow Leopard has a few new tricks up its sleeve, so whether you're new to Mac or a longtime Mac-thusiast, Mac expert Bob LeVitus has tips you'll appreciate. Learn how to start up your Mac, get to know the Dock and Finder, work your way through windows and dialogs, and organize and manage files and folders. Open the book and find: How to navigate around the Finder, Dock, and desktop Tips for opening, closing, resizing, and moving windows Steps for keeping Snow Leopard organized How to back up your system with Time Machine® Troubleshooting a

  6. Comparison of CSMA based MAC protocols of wireless sensor networks

    CERN Document Server

    singh, Himanshu

    2012-01-01

    Energy conservation has been an important area of interest in Wireless Sensor networks (WSNs). Medium Access Control (MAC) protocols play an important role in energy conservation. In this paper, we describe CSMA based MAC protocols for WSN and analyze the simulation results of these protocols. We implemented S-MAC, T-MAC, B-MAC, B-MAC+, X-MAC, DMAC and Wise-MAC in TOSSIM, a simulator which unlike other simulators simulates the same code running on real hardware. Previous surveys mainly focused on the classification of MAC protocols according to the techniques being used or problem dealt with and presented a theoretical evaluation of protocols. This paper presents the comparative study of CSMA based protocols for WSNs, showing which MAC protocol is suitable in a particular environment and supports the arguments with the simulation results. The comparative study can be used to find the best suited MAC protocol for wireless sensor networks in different environments.

  7. Mac OS X for Unix Geeks (Leopard)

    CERN Document Server

    Rothman, Ernest E; Rosen, Rich

    2009-01-01

    If you've been lured to Mac OS X because of its Unix roots, this invaluable book serves as a bridge between Apple's Darwin OS and the more traditional Unix systems. The new edition offers a complete tour of Mac OS X's Unix shell for Leopard and Tiger, and helps you find the facilities that replace or correspond to standard Unix utilities. Learn how to compile code, link to libraries, and port Unix software to Mac OS X and much more with this concise guide.

  8. Mac OS X Lion portable genius

    CERN Document Server

    Spivey, Dwight

    2012-01-01

    Two e-books, Mac OS X Lion Portable Genius and MacBook Pro Portable Genius, Third Edition, bundled in one package Books in the Portable Genius series provide readers with the most accessible, useful information possible, including plenty of tips and techniques for the most-used features in a product or software. These e-books will show you what you may not find out by just working with your MacBook Pro and OS X Lion. Genius icons present smart or innovative ways to do something, saving time and hassle. Easy-to-find information gives you the essentials plus insightful tips on how to navigate

  9. Office 2008 for Mac for dummies

    CERN Document Server

    LeVitus, Bob

    2013-01-01

    Office 2008 for Mac is here, with great new enhancements to all your favorite office productivity tools. Who better than "Dr. Mac, "Bob LeVitus, to show you how to load and use them all? From choosing the best version for your needs to managing your life with your online calendar, Office 2008 For Mac For Dummies covers what you need to know. It compares the Student/Teacher Edition, Standard Edition, and Professional Edition, then walks you through installing your preferred version and keeping it up to date. You'll find out all the things you can do with Word, Excel, PowerPoint, and Entourage,

  10. Wireless sensors networks MAC protocols analysis

    CERN Document Server

    Chaari, Lamia

    2010-01-01

    Wireless sensors networks performance are strictly related to the medium access mechanism. An effective one, require non-conventional paradigms for protocol design due to several constraints. An adequate equilibrium between communication improvement and data processing capabilities must be accomplished. To achieve low power operation, several MAC protocols already proposed for WSN. The aim of this paper is to survey and to analyze the most energy efficient MAC protocol in order to categorize them and to compare their performances. Furthermore we have implemented some of WSN MAC protocol under OMNET++ with the purpose to evaluate their performances.

  11. Beginning Mac OS X Snow Leopard programming

    CERN Document Server

    Trent, Michael

    2010-01-01

    Michael Trent is a technical reviewer for numerous books and magazine articles and the coauthor of Beginning Mac OS X Programming with Drew McCormack. Drew McCormack is an experienced computational scientist, founder of the ""The Mental Faculty""-an independent company developing software for the Mac and iPhone-and the coauthor of Beginning Mac OS X Programming with Michael Trent. Wrox Beginning guides are crafted to make learning programming languages and technologies easier than you think, providing a structured, tutorial format that will guide you through all the techniques involved.

  12. Learn Office 2011 for Mac OS X

    CERN Document Server

    Hart-Davis, Guy

    2011-01-01

    Office for Mac remains the leading productivity suite for Mac, with Apple's iWork and the free OpenOffice.org trailing far behind. And now it's being updated with a cleaner interface and more compatibility with Exchange and SharePoint. Learn Office 2011 for Mac OS X offers a practical, hands-on approach to using Office 2011 applications to create and edit documents and get work done efficiently. You'll learn how to customize Office, design, create, and share documents, manipulate data in a spreadsheet, and create lively presentations. You'll also discover how to organize your email, contacts,

  13. Relationship of blood cholesterol and apoprotein B levels to angiographically defined coronary artery disease in young males.

    Science.gov (United States)

    McGill, D A; Talsma, P; Ardlie, N G

    1993-03-01

    Coronary heart disease is mainly caused by the effects of obstruction to blood flow in the coronary arteries from discrete mural lesions that encroach into the lumen and usually occur in arteries that are involved by atherosclerosis. Even though the level of certain lipoproteins is indisputably related to the degree of this atherosclerotic involvement of the coronary arteries, the question of whether lipoproteins are also associated with the obstructive lesions remains uncertain. This study addressed the question in 53 males (age, 44.6 +/- 4.9 y) with premature coronary heart disease and angiographically proven coronary artery disease. The cholesterol, triglyceride, high-density lipoprotein, apoprotein B, and apoprotein A-I levels were compared by linear correlation to semiquantitative angiographic measures of coronary artery disease severity (coronary stenosis score and mean coronary stenosis score), the extent of mural involvement (coronary atheromatous score and mean coronary atheromatous score), and also the number of normal coronary artery segments, an alternative severity score (Jenkins), and left ventricular function score. Age, past and present cholesterol, low-density lipoprotein cholesterol, and apoprotein B levels correlated directly with the extent of disease (r = 0.27, 0.46, 0.29, 0.26, 0.35, respectively, P Multiple regression analysis was undertaken with lipoproteins and age as independent variables and angiographic scores as dependent variables; the apoprotein B level was the most predictive of the extent of coronary artery disease (P variables entered into the regression model, only age was independently predictive of the severity of angiographic coronary artery disease. Apoprotein B levels are not predictive of coronary artery disease severity but do predict independently the extent of involvement of coronary atherosclerosis defined angiographically.

  14. MAC Layer Hurdles in BSNs

    CERN Document Server

    Ullah, Sana; Choi, Young-Woo; Lee, Hyung-Soo; Kwak, Kyung Sup

    2009-01-01

    The last few decades have seen considerable research progress in microelectronics and integrated circuits, system-on-chip design, wireless communication, and sensor technology. This progress has enabled the seamless integration of autonomous wireless sensor nodes around a human body to create a Body Sensor Network (BSN). The development of a proactive and ambulatory BSN induces a number of enormous issues and challenges. This paper presents the technical hurdles during the design and implementation of a low-power Medium Access Control (MAC) protocol for in-body and on-body sensor networks. We analyze the performance of IEEE 802.15.4 protocol for the on-body sensor network. We also provide a comprehensive insight into the heterogeneous characteristics of the in-body sensor network. A low-power technique called Pattern-Based Wake-up Table is proposed to handle the normal traffic in a BSN. The proposed technique provides a reliable solution towards low-power communication in the in-body sensor network.

  15. H-MAC: A Hybrid MAC Protocol for Wireless Sensor Networks

    CERN Document Server

    Mehta, S; 10.5121/ijcnc.2010.2208

    2010-01-01

    In this paper, we propose a hybrid medium access control protocol (H-MAC) for wireless sensor networks. It is based on the IEEE 802.11's power saving mechanism (PSM) and slotted aloha, and utilizes multiple slots dynamically to improve performance. Existing MAC protocols for sensor networks reduce energy consumptions by introducing variation in an active/sleep mechanism. But they may not provide energy efficiency in varying traffic conditions as well as they did not address Quality of Service (QoS) issues. H-MAC, the propose MAC protocol maintains energy efficiency as well as QoS issues like latency, throughput, and channel utilization. Our numerical results show that H-MAC has significant improvements in QoS parameters than the existing MAC protocols for sensor networks while consuming comparable amount of energy.

  16. Learn Mac OS X Snow Leopard

    CERN Document Server

    Meyers, Scott

    2009-01-01

    You're smart and savvy, but also busy. This comprehensive guide to Apple's Mac OS X 10.6, Snow Leopard, gives you everything you need to know to live a happy, productive Mac life. Learn Mac OS X Snow Leopard will have you up and connected lickity split. With a minimum of overhead and a maximum of useful information, you'll cover a lot of ground in the time it takes other books to get you plugged in. If this isn't your first experience with Mac OS X, skip right to the "What's New in Snow Leopard" sections. You may also find yourself using this book as a quick refresher course or a way

  17. Macintosh Troubleshooting Pocket Guide for Mac OS

    CERN Document Server

    Lerner, David; Corporation, Tekserve

    2009-01-01

    The Macintosh Troubleshooting Pocket Guide covers the most common user hardware and software trouble. It's not just a book for Mac OS X (although it includes tips for OS X and Jaguar), it's for anyone who owns a Mac of any type-- there are software tips going back as far as OS 6. This slim guide distills the answers to the urgent questions that Tekserve's employee's answer every week into a handy guide that fits in your back pocket or alongside your keyboard.

  18. Enhanced Sleep Mode MAC Control for EPON

    DEFF Research Database (Denmark)

    Yan, Ying; Dittmann, Lars

    2011-01-01

    This paper introduces sleep mode operations for EPON. New MAC control functions are proposed to schedule sleep periods. Traffic profiles are considered to optimize energy efficiency and network performances. Simulation results are analyzed in OPNET modeler.......This paper introduces sleep mode operations for EPON. New MAC control functions are proposed to schedule sleep periods. Traffic profiles are considered to optimize energy efficiency and network performances. Simulation results are analyzed in OPNET modeler....

  19. 42 CFR 405.1120 - Filing briefs with the MAC.

    Science.gov (United States)

    2010-10-01

    ... 42 Public Health 2 2010-10-01 2010-10-01 false Filing briefs with the MAC. 405.1120 Section 405....1120 Filing briefs with the MAC. Upon request, the MAC will give the party requesting review, as well... ending with the date the brief is received by the MAC will not be counted toward the adjudication...

  20. 42 CFR 423.1974 - Medicare Appeals Council (MAC) review.

    Science.gov (United States)

    2010-10-01

    ... 42 Public Health 3 2010-10-01 2010-10-01 false Medicare Appeals Council (MAC) review. 423.1974..., MAC review, and Judicial Review § 423.1974 Medicare Appeals Council (MAC) review. An enrollee who is dissatisfied with an ALJ hearing decision may request that the MAC review the ALJ's decision or dismissal as...

  1. 42 CFR 423.2130 - Effect of the MAC's decision.

    Science.gov (United States)

    2010-10-01

    ... 42 Public Health 3 2010-10-01 2010-10-01 false Effect of the MAC's decision. 423.2130 Section 423... (CONTINUED) MEDICARE PROGRAM VOLUNTARY MEDICARE PRESCRIPTION DRUG BENEFIT Reopening, ALJ Hearings, MAC review, and Judicial Review § 423.2130 Effect of the MAC's decision. The MAC's decision is final and binding...

  2. 42 CFR 405.1130 - Effect of the MAC's decision.

    Science.gov (United States)

    2010-10-01

    ... 42 Public Health 2 2010-10-01 2010-10-01 false Effect of the MAC's decision. 405.1130 Section 405....1130 Effect of the MAC's decision. The MAC's decision is final and binding on all parties unless a Federal district court issues a decision modifying the MAC's decision or the decision is revised as the...

  3. 42 CFR 423.2118 - Obtaining evidence from the MAC.

    Science.gov (United States)

    2010-10-01

    ... 42 Public Health 3 2010-10-01 2010-10-01 false Obtaining evidence from the MAC. 423.2118 Section..., MAC review, and Judicial Review § 423.2118 Obtaining evidence from the MAC. An enrollee may request... the costs of providing these items. If an enrollee requests evidence from the MAC and an opportunity...

  4. 42 CFR 423.2126 - Case remanded by the MAC.

    Science.gov (United States)

    2010-10-01

    ... 42 Public Health 3 2010-10-01 2010-10-01 false Case remanded by the MAC. 423.2126 Section 423.2126... (CONTINUED) MEDICARE PROGRAM VOLUNTARY MEDICARE PRESCRIPTION DRUG BENEFIT Reopening, ALJ Hearings, MAC review, and Judicial Review § 423.2126 Case remanded by the MAC. (a) When the MAC may remand a case to the ALJ...

  5. 42 CFR 423.2120 - Filing briefs with the MAC.

    Science.gov (United States)

    2010-10-01

    ... 42 Public Health 3 2010-10-01 2010-10-01 false Filing briefs with the MAC. 423.2120 Section 423... (CONTINUED) MEDICARE PROGRAM VOLUNTARY MEDICARE PRESCRIPTION DRUG BENEFIT Reopening, ALJ Hearings, MAC review, and Judicial Review § 423.2120 Filing briefs with the MAC. Upon request, the MAC will give the...

  6. Secure MAC for Wireless Sensor Networks through RBFNN

    Directory of Open Access Journals (Sweden)

    P.Sankara Rao

    2010-08-01

    Full Text Available This paper discusses an application of a neural network in wireless sensor network security. It presents a Radial Basic Function Neural Network based media access control protocol (MAC to secure a CSMA-based wireless sensor network against the denial-of-service attacks launched by adversaries. The Radial Basic Function Neural Network enhances the security of a WSN by constantly monitoring the parameters that exhibit unusual variations in case of an attack. The RBFN shuts down the MAC layer and the physical layer of the sensor node when the suspicion factor, the output of the MLP, exceeds a preset threshold level. The MLP-guarded secure WSN is implemented using the Prowler simulator. Simulation results show that the MLP helps in extending the lifetime of the WSN.

  7. MacMath 92 a dynamical systems software package for the Macintosh

    CERN Document Server

    Hubbard, John H

    1993-01-01

    MacMath is a scientific toolkit for the Macintosh computer consisting of twelve graphics programs. It supports mathematical computation and experimentation in dynamical systems, both for differential equations and for iteration. The MacMath package was designed to accompany the textbooks Differential Equations: A Dynamical Systems Approach Part I & II. The text and software was developed for a junior-senior level course in applicable mathematics at Cornell University, in order to take advantage of excellent and easily accessible graphics. MacMath addresses differential equations and iteration such as: analyzer, diffeq, phase plane, diffeq 3D views, numerical methods, periodic differential equations, cascade, 2D iteration, eigenfinder, jacobidraw, fourier, planets. These versatile programs greatly enhance the understanding of the mathematics in these topics. Qualitative analysis of the picture leads to quantitative results and even to new mathematics. This new edition includes the latest version of the Mac...

  8. SA-MAC:Self-Stabilizing Adaptive MAC Protocol for Wireless Sensor Networks

    Institute of Scientific and Technical Information of China (English)

    波澄; 韩君泽; 李向阳; 王昱; 肖波

    2014-01-01

    A common method of prolonging the lifetime of wireless sensor networks is to use low power duty cycling protocol. Existing protocols consist of two categories: sender-initiated and receiver-initiated. In this paper, we present SA-MAC, a self-stabilizing adaptive MAC protocol for wireless sensor networks. SA-MAC dynamically adjusts the transmission time-slot, waking up time-slot, and packet detection pattern according to current network working condition, such as packet length and wake-up patterns of neighboring nodes. In the long run, every sensor node will find its own transmission phase so that the network will enter a stable stage when the network load and qualities are static. We conduct extensive experiments to evaluate the energy consumption, packet reception rate of SA-MAC in real sensor networking systems. Our results indicate that SA-MAC outperforms other existing protocols.

  9. Development of the "Three-step MACS": a novel strategy for isolating rare cell populations in the absence of known cell surface markers from complex animal tissue.

    Science.gov (United States)

    Lee, Mathia Y; Lufkin, Thomas

    2012-07-01

    To circumvent the difficulty of isolating specific cell populations by MACS from dissociated complex animal tissue, when their proportions reached levels similar to that of the background, we developed the "Three-step MACS" strategy. Cells of interest are defined by their expression of a particular gene(s) of interest rather by than their natural cell surface markers or size. A two-component transgenic cell surface protein, for two sequential rounds of MACS, is expressed under the promoter control of the endogenous gene of interest by means of gene targeting and the generation of transgenic tissue. An initial step to remove dead cells is also used. Here, we describe proof-of-concept experiments, using the biotin acceptor peptide (BAP)-low-affinity nerve growth factor receptor as the two-component protein. The first component, the BAP, can be biotinylated in specific subsets of cells expressing a particular gene by expressing the biotinylating enzyme, hBirA = humanized BirA (hBirA), under the promoter control of another gene defining the specific subpopulation. We showed that a rare population of cells (1.1% of the 13.5 days postcoital mouse embryo) could be enriched to a sufficiently high purity (84.4%). From another sample with 0.1% of our cells of interest, we achieved a 40.3% pure sample. The low cost, speed, and technical ease of the Three-step MACS also make it scalable and hence, an ideal method for preparing sufficient quantities of biological samples for sensitive, high-throughput assays.

  10. Mac OS X Snow Leopard试用

    Institute of Scientific and Technical Information of China (English)

    大大

    2009-01-01

    苹果新一代操作系统Mac OS X 10.6 Snow Leopard(雪豹)于8月底上市。根据NPD集团的统计数据,该系统在美国市场前两周的销售非常喜人,是2007年Mac OS X 10.5 Leopard上市销量的2倍以上,是2005年的Mac OS X 10.4 Tiger操作系统的售量的4倍。假如你也对升级价格仅需88元雪豹系统感兴趣,就让我们从一起升级安装开始,体验它独特的魅力。

  11. MacBook Pro Portable Genius

    CERN Document Server

    Miser, Brad

    2011-01-01

    Tips and techniques for forward-thinking MacBook Pro users Now that you have a MacBook Pro, you need just one more accessory, your very own copy of MacBook Pro Portable Genius, Third Edition. This handy, compact book lets you in on a wealth of tips and tricks, so you get the very most out of Apple's very popular notebook. Discover the latest on the most recent release of iLife, get the skinny on the new Intel Core i7 and i5 processors in the Pro, see how to go wireless in a smart way, and much more. The book is easy to navigate, doesn't skimp on the essentials, and helps you save time and avoi

  12. MacSelfService online tutorial

    CERN Document Server

    CERN. Geneva

    2016-01-01

    Mac Self-Service is a functionality within the Mac Desktop Service built and maintained to empower CERN users by giving them easy access to applications and configurations through the Self-Service application. This tutorial (text attached to the event page) explains how to install Mac Self-Service and how to use it to install applications and printers. Content owner: Vincent Nicolas Bippus Presenter: Pedro Augusto de Freitas Batista Tell us what you think via e-learning.support at cern.ch More tutorials in the e-learning collection of the CERN Document Server (CDS) https://cds.cern.ch/collection/E-learning%20modules?ln=en All info about the CERN rapid e-learning project is linked from http://twiki.cern.ch/ELearning  

  13. TraPy-MAC: Traffic Priority Aware Medium Access Control Protocol for Wireless Body Area Network.

    Science.gov (United States)

    Ullah, Fasee; Abdullah, Abdul Hanan; Kaiwartya, Omprakash; Cao, Yue

    2017-06-01

    Recently, Wireless Body Area Network (WBAN) has witnessed significant attentions in research and product development due to the growing number of sensor-based applications in healthcare domain. Design of efficient and effective Medium Access Control (MAC) protocol is one of the fundamental research themes in WBAN. Static on-demand slot allocation to patient data is the main approach adopted in the design of MAC protocol in literature, without considering the type of patient data specifically the level of severity on patient data. This leads to the degradation of the performance of MAC protocols considering effectiveness and traffic adjustability in realistic medical environments. In this context, this paper proposes a Traffic Priority-Aware MAC (TraPy-MAC) protocol for WBAN. It classifies patient data into emergency and non-emergency categories based on the severity of patient data. The threshold value aided classification considers a number of parameters including type of sensor, body placement location, and data transmission time for allocating dedicated slots patient data. Emergency data are not required to carry out contention and slots are allocated by giving the due importance to threshold value of vital sign data. The contention for slots is made efficient in case of non-emergency data considering threshold value in slot allocation. Moreover, the slot allocation to emergency and non-emergency data are performed parallel resulting in performance gain in channel assignment. Two algorithms namely, Detection of Severity on Vital Sign data (DSVS), and ETS Slots allocation based on the Severity on Vital Sign (ETS-SVS) are developed for calculating threshold value and resolving the conflicts of channel assignment, respectively. Simulations are performed in ns2 and results are compared with the state-of-the-art MAC techniques. Analysis of results attests the benefit of TraPy-MAC in comparison with the state-of-the-art MAC in channel assignment in realistic medical

  14. Mac OS X Snow Leopard pocket guide

    CERN Document Server

    Seiblod, Chris

    2009-01-01

    Whether you're new to the Mac or a longtime user, this handy book is the quickest way to get up to speed on Snow Leopard. Packed with concise information in an easy-to-read format, Mac OS X Snow Leopard Pocket Guide covers what you need to know and is an ideal resource for problem-solving on the fly. This book goes right to the heart of Snow Leopard, with details on system preferences, built-in applications, and utilities. You'll also find configuration tips, keyboard shortcuts, guides for troubleshooting, lots of step-by-step instructions, and more. Learn about new features and changes s

  15. MacBook Pro Portable Genius

    CERN Document Server

    Miser, Brad

    2012-01-01

    Discover loads of tips and techniques for the newest MacBook Pro You're already ahead of the game with a MacBook Pro. Now you can get even more out the popular Apple notebook with the new edition of this handy, compact book. Crammed with savvy insights and tips on key tools and shortcuts, this book will help you increase your productivity and keep your Apple digital lifestyle on track. From desktop sharing and wireless networking to running Windows applications, this book avoids fluff, doesn't skimp on the essentials, saves you time and hassle, and shows you what you most want to know. Include

  16. MAC2: A Multi-Hop Adaptive MAC Protocol with Packet Concatenation for Wireless Sensor Networks

    Science.gov (United States)

    Nguyen, Kien; Meis, Ulrich; Ji, Yusheng

    Wireless sensor network MAC protocols switch radios off periodically, employing the so-called duty cycle mechanism, in order to conserve battery power that would otherwise be wasted by energy-costly idle listening. In order to minimize the various negative side-effects of the original scheme, especially on latency and throughput, various improvements have been proposed. In this paper, we introduce a new MAC protocol called MAC2(Multi-hop Adaptive with packet Concatenation-MAC) which combines three promising techniques into one protocol. Firstly, the idea to forward packets over multiple hops within one operational cycle as initially introduced in RMAC. Secondly, an adaptive method that adjusts the listening period according to traffic load minimizing idle listening. Thirdly, a packet concatenation scheme that not only increases throughput but also reduces power consumption that would otherwise be incurred by additional control packets. Furthermore, MAC2 incorporates the idea of scheduling data transmissions with minimum latency, thereby performing packet concatenation together with the multi-hop transmission mechanism in a most efficient way. We evaluated MAC2 using the prominent network simulator ns-2 and the results show that our protocol can outperform DW-MAC — a state of the art protocol both in terms of energy efficiency and throughput.

  17. Project MAC Progress Report 11

    Science.gov (United States)

    1974-12-01

    generalized to (( MPLUS ) SX 1). Here we see that user-defined variables are lexically modified by adding a dollar sign so that they do not accidentally...in the simplified form of the expression which is (( MPLUS SIMP) 1 8X). The simplified expression has been sorted and its operator list contains the...indicator SiMP which will prevent resimplification of the expression. After factoring the expression, we would obtain (( MPLUS SIMP IRREDUCIBLE) 1 SX

  18. Computing the Chern–Schwartz–MacPherson class of complete simplical toric varieties

    DEFF Research Database (Denmark)

    Helmer, Martin

    2017-01-01

    Topological invariants such as characteristic classes are an important tool to aid in understanding and categorizing the structure and properties of algebraic varieties. In this note, we consider the problem of computing a particular characteristic class, the Chern–Schwartz–MacPherson class......, of a complete simplicial toric variety X∑ defined by a fan ∑ from the combinatorial data contained in the fan ∑. Specifically, we give an effective combinatorial algorithm to compute the Chern–Schwartz–MacPherson class of X∑, in the Chow ring (or rational Chow ring) of X∑. This method is formulated by combining...

  19. Defining excellence.

    Science.gov (United States)

    Mehl, B

    1993-05-01

    Excellence in the pharmacy profession, particularly pharmacy management, is defined. Several factors have a significant effect on the ability to reach a given level of excellence. The first is the economic and political climate in which pharmacists practice. Stricter controls, reduced resources, and the velocity of change all necessitate nurturing of values and a work ethic to maintain excellence. Excellence must be measured by the services provided with regard to the resources available; thus, the ability to achieve excellence is a true test of leadership and innovation. Excellence is also time dependent, and today's innovation becomes tomorrow's standard. Programs that raise the level of patient care, not those that aggrandize the profession, are the most important. In addition, basic services must be practiced at a level of excellence. Quality assessment is a way to improve care and bring medical treatment to a higher plane of excellence. For such assessment to be effective and not punitive, the philosophy of the program must be known, and the goal must be clear. Excellence in practice is dependent on factors such as political and social norms, standards of practice, available resources; perceptions, time, the motivation to progress to a higher level, and the continuous innovation required to reshape the profession to meet the needs of society.

  20. Halothane concentrations required to block the cardiovascular responses to incision (MAC CVR) in infants and children.

    Science.gov (United States)

    Ishizawa, Y; Dohi, S

    1993-01-01

    The purpose of this study was to determine the halothane concentration in N2O required to block the cardiovascular responses to skin incision (MAC CVR) in infants and children. We studied 64 unpremedicated ASA 1 infants and children (one month to seven years). In each infant or child, anaesthesia was induced slowly with halothane and N2O, and an endotracheal tube was placed. The MAC CVR was assessed, after a steady state end-tidal halothane concentration had been established for ten minutes, by the "up and down technique" of Dixon. Positive responses were defined as an increase in MAP or HR > 10%. The MAC CVR50 values of halothane with 60% N2O were 1.16 +/- 0.23% at 1-6 mo, 1.17 +/- 0.18% at 7-12 mo, 0.95 +/- 0.26% at 1-3 yr, and 1.12 +/- 0.16% at 4-7 yr. The value at 1-3 years children was less than those in the other age groups (P values of MAC CVR50 of halothane in infants and children are higher than those required to block motor responses (MAC). The halothane requirement to block cardiovascular responses is lowest in the children aged one to three years.

  1. Efficient MAC Protocol for Hybrid Wireless Network with Heterogeneous Sensor Nodes

    Directory of Open Access Journals (Sweden)

    Md. Nasre Alam

    2016-01-01

    Full Text Available Although several Directional Medium Access Control (DMAC protocols have been designed for use with homogeneous networks, it can take a substantial amount of time to change sensor nodes that are equipped with an omnidirectional antenna for sensor nodes with a directional antenna. Thus, we require a novel MAC protocol for use with an intermediate wireless network that consists of heterogeneous sensor nodes equipped with either an omnidirectional antenna or a directional antenna. The MAC protocols that have been designed for use in homogeneous networks are not suitable for use in a hybrid network due to deaf, hidden, and exposed nodes. Therefore, we propose a MAC protocol that exploits the characteristics of a directional antenna and can also work efficiently with omnidirectional nodes in a hybrid network. In order to address the deaf, hidden, and exposed node problems, we define RTS/CTS for the neighbor (RTSN/CTSN and Neighbor Information (NIP packets. The performance of the proposed MAC protocol is evaluated through a numerical analysis using a Markov model. In addition, the analytical results of the MAC protocol are verified through an OPNET simulation.

  2. Results from the MAC Vertex chamber

    Energy Technology Data Exchange (ETDEWEB)

    Nelson, H.N.

    1987-05-01

    The design, construction, and performance characteristics of a high precision gaseous drift chamber made of thin walled proportional tubes are described. The device achieved an average spatial resolution of 45 ..mu..m in use for physics analysis with the MAC detector. The B-lifetime result obtained with this chamber is discussed.

  3. MacIntyre, Managerialism and Universities

    Science.gov (United States)

    Stolz, Steven A.

    2017-01-01

    MacIntyre's earlier work and concern with social science enquiry not only exposes its limits, but also provides an insight into how its knowledge claims have been put to ideological use. He maintains that the institutional embodiment of these ideological ideas is the bureaucratic manager who has had a negative role to play in social structures…

  4. AH-MAC: Adaptive Hierarchical MAC Protocol for Low-Rate Wireless Sensor Network Applications

    Directory of Open Access Journals (Sweden)

    Adnan Ismail Al-Sulaifanie

    2017-01-01

    Full Text Available This paper proposes an adaptive hierarchical MAC protocol (AH-MAC with cross-layer optimization for low-rate and large-scale wireless sensor networks. The main goal of the proposed protocol is to combine the strengths of LEACH and IEEE 802.15.4 while offsetting their weaknesses. The predetermined cluster heads are supported with an energy harvesting circuit, while the normal nodes are battery-operated. To prolong the network’s operational lifetime, the proposed protocol transfers most of the network’s activities to the cluster heads while minimizing the node’s activity. Some of the main features of this protocol include energy efficiency, self-configurability, scalability, and self-healing. The simulation results showed great improvement of the AH-MAC over LEACH protocol in terms of energy consumption and throughput. AH-MAC consumes eight times less energy while improving throughput via acknowledgment support.

  5. CA-MAC: A Novel MAC Protocol to Alleviate Congestion in Wireless Sensor Networks

    Directory of Open Access Journals (Sweden)

    WU, J.

    2013-11-01

    Full Text Available Even if the traffic pattern is known and the network topology is simple, a strong congestion can take place in wireless sensor networks (WSNs due to the data gathering effect and the duty-cycle operation. In this paper, we propose a novel medium access control (MAC protocol to alleviate the congestion, which is referred to as the congestion alleviation-MAC (CA-MAC. It adopts an adaptive contention window (ACW, which allows the nodes with more buffered packets to transmit with a higher probability, as well as an intelligent burst packet transmission when the congested nodes seize the channel. Simulations are performed in NS-2, and results show that the proposed CA-MAC protocol achieves a good performance in terms of the packet delivery ratio (PDR, power consumption, throughput, and average latency.

  6. Exposure histories of lunar meteorites: ALHA81005, MAC88104, MAC88105, and Y791197

    Energy Technology Data Exchange (ETDEWEB)

    Nishiizumi, K.; Arnold, J.R. (Univ. of California, San Diego, (United States)); Klein, J.; Fink, D.; Middleton, R. (Univ. of Pennsylvania, Philadelphia (United States)); Kubik, P.W.; Sharma, P.; Elmore, D. (Univ. of Rochester, NY (United States)); Reedy, R.C. (Los Alamos National Lab., NM (United States))

    1991-11-01

    The cosmogenic radionuclides {sup 41}Ca, {sup 36}Cl, {sup 26}Al, and {sup 10}Be in the Allan Hills 81005, MacAlpine Hills 88104, MacAlpine Hills 88105,and Yamato 791197 meteorites were measured by accelerator mass spectrometry (AMS). {sup 53}Mn in Allan Hills 81005 and Yamato 791197 was measured by activation. These four lunar meteorites experienced similar histories. They were ejected from near the surface of the Moon ranging in depth down to 400 g/cm{sup 2} and had very short transition times (less than 0.1 Ma) from the Moon to the Earth. A comparison of the cosmogenic nuclide concentrations in MacAlpine Hills 88104 and MacAlpine Hills 88105 clearly indicates that they are a pair from the same fall.

  7. 42 CFR 405.1126 - Case remanded by the MAC.

    Science.gov (United States)

    2010-10-01

    ... 42 Public Health 2 2010-10-01 2010-10-01 false Case remanded by the MAC. 405.1126 Section 405.1126....1126 Case remanded by the MAC. (a) When the MAC may remand a case. Except as specified in § 405.1122(c), the MAC may remand a case in which additional evidence is needed or additional action by the ALJ is...

  8. Reduction in standard MAC and MAC for intubation after clonidine premedication in children.

    Science.gov (United States)

    Inomata, S; Kihara, S; Yaguchi, Y; Baba, Y; Kohda, Y; Toyooka, H

    2000-11-01

    We examined the relative effects of different doses of oral clonidine on the MAC for endotracheal intubation (MACEI) and the MAC for skin incision (MAC) in children. We studied 90 children (15 in each group) (age range 2-8 yr, weight 10-27 kg, height 89-124 cm) who received one of three preanaesthetic medications: placebo (control), oral clonidine 2 micrograms kg-1, or oral clonidine 4 micrograms kg-1 100 min before anaesthesia. Anaesthesia was induced and maintained with sevoflurane in oxygen and air without i.v. anesthetics and neuromuscular relaxants. The end-tidal sevoflurane concentration was kept constant for > or = 15 min before tracheal intubation or skin incision. MACs were determined using Dixon's 'up-and-down method'. Mean (SD) MACEIs of sevoflurane were 2.9 (0.1)%, 2.5 (0.1)% and 1.9 (0.1)% (P clonidine 2 micrograms kg-1 and clonidine 4 micrograms kg-1 groups. The MACEIs and MACs decreased dose-dependently. The MACEI/MAC ratio (1.4) was not affected by clonidine.

  9. 42 CFR 423.2128 - Action of the MAC.

    Science.gov (United States)

    2010-10-01

    ... 42 Public Health 3 2010-10-01 2010-10-01 false Action of the MAC. 423.2128 Section 423.2128 Public...) MEDICARE PROGRAM VOLUNTARY MEDICARE PRESCRIPTION DRUG BENEFIT Reopening, ALJ Hearings, MAC review, and Judicial Review § 423.2128 Action of the MAC. (a) After it has reviewed all the evidence in the...

  10. 42 CFR 405.1118 - Obtaining evidence from the MAC.

    Science.gov (United States)

    2010-10-01

    ... 42 Public Health 2 2010-10-01 2010-10-01 false Obtaining evidence from the MAC. 405.1118 Section... Council Review § 405.1118 Obtaining evidence from the MAC. A party may request and receive a copy of all... these items. If a party requests evidence from the MAC and an opportunity to comment on that evidence...

  11. 42 CFR 405.1128 - Action of the MAC.

    Science.gov (United States)

    2010-10-01

    ... 42 Public Health 2 2010-10-01 2010-10-01 false Action of the MAC. 405.1128 Section 405.1128 Public... the MAC. (a) After it has reviewed all the evidence in the administrative record and any additional evidence received, subject to the limitations on MAC consideration of additional evidence in § 405.1122...

  12. 42 CFR 422.608 - Medicare Appeals Council (MAC) review.

    Science.gov (United States)

    2010-10-01

    ... 42 Public Health 3 2010-10-01 2010-10-01 false Medicare Appeals Council (MAC) review. 422.608... and Appeals § 422.608 Medicare Appeals Council (MAC) review. Any party to the hearing, including the MA organization, who is dissatisfied with the ALJ hearing decision, may request that the MAC review...

  13. MAC 700 Wash高亮度灯具

    Institute of Scientific and Technical Information of China (English)

    2006-01-01

    马田最新推出的MAC 700 Wash高亮度灯具继承了MAC系列的传统优点.具有与MAC 700 Profile相同的强大功能、模组桔构和出色设计,是MAC 700 Profile的“最佳搭档”。

  14. Autonomous Power Control MAC Protocol for Mobile Ad Hoc Networks

    Directory of Open Access Journals (Sweden)

    2006-01-01

    Full Text Available Battery energy limitation has become a performance bottleneck for mobile ad hoc networks. IEEE 802.11 has been adopted as the current standard MAC protocol for ad hoc networks. However, it was developed without considering energy efficiency. To solve this problem, many modifications on IEEE 802.11 to incorporate power control have been proposed in the literature. The main idea of these power control schemes is to use a maximum possible power level for transmitting RTS/CTS and the lowest acceptable power for sending DATA/ACK. However, these schemes may degrade network throughput and reduce the overall energy efficiency of the network. This paper proposes autonomous power control MAC protocol (APCMP, which allows mobile nodes dynamically adjusting power level for transmitting DATA/ACK according to the distances between the transmitter and its neighbors. In addition, the power level for transmitting RTS/CTS is also adjustable according to the power level for DATA/ACK packets. In this paper, the performance of APCMP protocol is evaluated by simulation and is compared with that of other protocols.

  15. On Proper Selection of Multihop Relays for Future Enhancement of AeroMACS Networks

    Science.gov (United States)

    Kamali, Behnam; Kerczewski, Robert J.; Apaza, Rafael D.

    2015-01-01

    As the Aeronautical Mobile Airport Communications System (AeroMACS) has evolved from a technology concept to a deployed communications network over major US airports, it is now time to contemplate whether the existing capacity of AeroMACS is sufficient to meet the demands set forth by all fixed and mobile applications over the airport surface given the AeroMACS constraints regarding bandwidth and transmit power. The underlying idea in this article is to present IEEE 802.16j-based WiMAX as a technology that can address future capacity enhancements and therefore is most feasible for AeroMACS applications. The principal argument in favor IEEE 802.16j technology is the flexible and cost effective extension of radio coverage that is afforded by relay fortified networks, with virtually no increase in the power requirements and virtually no rise in interference levels to co-allocated applications. The IEEE 802.16j-based multihop relay systems are briefly described. The focus is on key features of this technology, frame structure, and its architecture. Next, AeroMACS is described as a WiMAX-based wireless network. The two major relay modes supported by IEEE 802.16j amendment, i.e., transparent and non-transparent are described. The benefits of employing multihop relays are listed. Some key challenges related to incorporating relays into AeroMACS networks are discussed. The selection of relay type in a broadband wireless network affects a number of network parameters such as latency, signal overhead, PHY (Scalable Physical Layer) and MAC (Media Access Layer) layer protocols, consequently it can alter key network quantities of throughput and QoS (Quality of Service).

  16. Isolation and characterisation of human gingival margin-derived STRO-1/MACS1 and MACS2 cell populations

    Institute of Scientific and Technical Information of China (English)

    Karim M Fawzy El-Sayed; Sebastian Paris; Christian Graetz; Neemat Kassem; Mohamed Mekhemar; Hendrick Ungefroren; Fred Fandrich; Christof Dorfer

    2015-01-01

    Recently, gingival margin-derived stem/progenitor cells isolated via STRO-1/magnetic activated cell sorting (MACS) showed remarkable periodontal regenerative potential in vivo. As a second-stage investigation, the present study’s aim was to perform in vitro characterisation and comparison of the stem/progenitor cell characteristics of sorted STRO-1-positive (MACS1) and STRO-1-negative (MACS2) cell populations from the human free gingival margin. Cells were isolated from the free gingiva using a minimally invasive technique and were magnetically sorted using anti-STRO-1 antibodies. Subsequently, the MACS1 and MACS2 cell fractions were characterized by flow cytometry for expression of CD14, CD34, CD45, CD73, CD90, CD105, CD146/MUC18 and STRO-1. Colony-forming unit (CFU) and multilineage differentiation potential were assayed for both cell fractions. Mineralisation marker expression was examined using real-time polymerase chain reaction (PCR). MACS1 and MACS2 cell fractions showed plastic adherence. MACS1 cells, in contrast to MACS2 cells, showed all of the predefined mesenchymal stem/progenitor cell characteristics and a significantly higher number of CFUs (P,0.01). More than 95%of MACS1 cells expressed CD105, CD90 and CD73;lacked the haematopoietic markers CD45, CD34 and CD14, and expressed STRO-1 and CD146/MUC18. MACS2 cells showed a different surface marker expression profile, with almost no expression of CD14 or STRO-1, and more than 95%of these cells expressed CD73, CD90 and CD146/MUC18, as well as the haematopoietic markers CD34 and CD45 and CD105. MACS1 cells could be differentiated along osteoblastic, adipocytic and chondroblastic lineages. In contrast, MACS2 cells demonstrated slight osteogenic potential. Unstimulated MACS1 cells showed significantly higher expression of collagen I (P,0.05) and collagen III (P,0.01), whereas MACS2 cells demonstrated higher expression of osteonectin (P,0.05;Mann–Whitney). The present study is the first to compare gingival

  17. MacBook All-in-One For Dummies

    CERN Document Server

    Chambers, Mark L

    2011-01-01

    Get comfortable and confident with your MacBook! Combining the fun-but-straightforward content of nine minibooks, this new edition of MacBook All-in-One For Dummies delivers helpful coverage of the rich features and essential tools you need to know to use the MacBook to its fullest potential. You'll learn an array of MacBook basics while veteran author Mark Chambers walks you through setting up your MacBook, running programs, finding files with Finder, searching with Spotlight, keeping track with Address Book, enjoying music with iTunes, creating cool multimedia projects with iLife, and more.

  18. Seán MacDiarmada

    Directory of Open Access Journals (Sweden)

    Madden

    2016-12-01

    Full Text Available Seán MacDiarmada: Signatory to Proclamation – Executed after the Rising of 1916 - Leitrim to Kilmainham was written by Tom Madden to coincide with the 1916/2016 centenary commemorations. The play was first performed at the Mullagh Arts Festival in Cavan during September 2016 and provides a lively account of the background and activism of one the seven leaders of the Easter Rising of 1916. The action plays out over twelve scenes taking in MacDiarmada's journey from teacher to revolutionary activist culminating in a deeply flawed court-martial and his subsequent execution by a British Army firing squad on May 12th, 1916.

  19. Earth tides in MacDonald's model

    CERN Document Server

    Ferraz-Mello, S

    2013-01-01

    We expand the equations used in MacDonald's 1964 theory and Fourier analyze the tidal variations of the height at one point on the Earth surface, and also the tidal potential at such point. It is shown that no intrinsic law is relating the lag of the tide components to their frequencies. In other words, no simple rheology is being intrinsically fixed by MacDonald's equations. The same is true of the modification proposed by Singer(1968). At variance with these two cases, the modification proposed by Williams and Efroimsky (2012) fix the standard Darwin rheology in which the lags are proportional to the frequencies and their model is, in this sense, equivalent to Mignard's 1979 formulation of Darwin's theory.

  20. MacBook Pro portable genius

    CERN Document Server

    Gruman, Galen

    2013-01-01

    Learn the skills, tools and shortcuts you need in order to make the most of your MacBook Pro This easy-to-use, compact guide skips the fluff and gets right to the essentials so that you can maximize all the latest features of the MacBook Pro. Packed with savvy insights and tips on key tools and shortcuts, this handy book aims to help you increase your productivity and save you time and hassle. From desktop sharing and wireless networking to running Windows applications and more, this book shows you what you want to know. Includes the latest version of OS X, iCloud, FaceTime, and moreCovers al

  1. Performance Analysis of MAC Layer Protocols in Wireless Sensor Network

    Directory of Open Access Journals (Sweden)

    Hameeza Ahmed

    2014-10-01

    Full Text Available Media Access Control (MAC layer protocols have a critical role in making a typical Wireless Sensor Network (WSN more reliable and efficient. Choice of MAC layer protocol and other factors including number of nodes, mobility, traffic rate and playground size dictates the performance of a particular WSN. In this paper, the performance of an experimental WSN is evaluated using different MAC layer protocols. In this experiment, a WSN is created using OMNeT++ MiXiM network simulator and its performance in terms of packet delivery ratio and mean latency is evaluated. The simulation results show that IEEE 802.11 MAC layer protocol performs better than CSMA, B-MAC and IEEE 802.15.4 MAC layer protocols. In the considered scenario, IEEE 802.15.4 is ranked second in performance, followed by CSMA and B-MAC.

  2. Masked Hypertension Defined by Ambulatory Blood Pressure Monitoring Is Associated With an Increased Serum Glucose Level and Urinary Albumin-Creatinine Ratio

    Science.gov (United States)

    Ishikawa, Joji; Hoshide, Satoshi; Eguchi, Kazuo; Schwartz, Joseph E.; Pickering, Thomas G.; Shimada, Kazuyuki; Kario, Kazuomi

    2017-01-01

    The authors evaluated the relationship of hypertensive target organ damage to masked hypertension assessed by ambulatory blood pressure (BP) and home blood pressure (HBP) monitoring in 129 participants without taking antihypertensive medication. Masked hypertension was defined as office BP ≤140/90 mm Hg and 24-hour ambulatory BP ≥130/80 mm Hg. The masked hypertensive participants defined by 24-hour ambulatory BP (n=13) had a higher serum glucose level (126 vs 96 mg/dL, P=.001) and urinary albumin-creatinine ratio (38.0 vs 7.5 mg/gCr, P<.001) than the normotensive participants (n=74); however, these relationships were not observed when the authors defined groups using HBP (≥135/85 mm Hg). Masked hypertension by both 24-hour ambulatory BP and HBP had a higher urinary albumin-creatinine ratio than normotension by both 24-hour ambulatory BP and HBP (62.1 vs 7.4 mg/gCr, P=.001), and than masked hypertension by HBP alone (9.3 mg/gCr, P=.009). Masked hypertension defined by 24-hour ambulatory BP is associated with an increased serum glucose level and urinary albumin-creatinine ratio, but these relationships are not observed in masked hypertension defined by HBP. PMID:20695934

  3. Simultaneous mobilization of Mac-1 (CD11b/CD18) and formyl peptide chemoattractant receptors in human neutrophils.

    Science.gov (United States)

    Graves, V; Gabig, T; McCarthy, L; Strour, E F; Leemhuis, T; English, D

    1992-08-01

    Mobilization of a distinct subset of specific granules provides a physiologically important mechanism to recruit Mac-1 (CD11b/CD18) from an intracellular pool to the external surface of the neutrophil plasma membrane, where the functionally active heterodimer mediates several adherence-dependent processes that are crucial for adequate host defense and cellular inflammatory responses. We observed similar characteristics for translocation of Mac-1 and neutrophil formyl peptide receptors (FPR) and hypothesize that the readily accessible pools of both Mac-1 and FPR are colocalized within this specific granule subset. Plasma membrane levels of both FPR (assessed with 3H-FMLP) and Mac-1 (assessed by fluorescence-activated cell sorter analysis of fluorescein isothiocyanate [FITC]-Mo-1-labeled cells) were markedly downregulated in cells prepared at low temperature from blood cooled to 4 degrees C immediately after removal from the circulation. Levels of both FPR and Mac-1 remained low on cells held at 4 degrees C. Upon warming, spontaneous upregulation of Mac-1 and FPR occurred with similar kinetics and temperature dependency. Translocation of both Mac-1 and FPR was markedly potentiated by exposure of cells to either fluoride ion (which has been shown by others to specifically elicit exocytosis of gelatinase-rich and vitamin B-12 binding protein-poor granules) or granulocyte-macrophage colony-stimulating factor (GM-CSF), a cytokine that markedly potentiates the neutrophils' host defense capabilities. Levels of both FPR and Mac-1 on F-- or GM-CSF-treated neutrophils exceeded those present on cells incubated at 37 degrees C for extended time intervals, indicating that stimulated translocation may involve mobilization of an additional granule subset. Scatchard analysis showed that only low-affinity FPR were translocated during spontaneous and stimulus-dependent upregulation. To directly compare FPR levels on the surface of cells displaying varying levels of Mac-1 within a

  4. 关于Mac OS X Lion

    Institute of Scientific and Technical Information of China (English)

    饭桶

    2011-01-01

    Lion是Mac OS X操作系统的第七个版本,第一个版本是2001年发布的Cheetah(猎豹).或许很多Windows用户会认为,Lion不过是一次升级,主版本仍然是Mac OSX.那么我不介意稍微解释一下:Mac OS X对应的层次是Windows,Cheetah或者Lion相当于XP,或者7.因此即使从软件工程的角度看,Lion也是一个全新的操作系统.由于重新编译了核心,Lion的安装文件只有3.6GB大小,比上一代(Snow Leopard)减少了近一半的体积,这种比旧版本体积更小的新操作系统在历史上可不多见.

  5. Power Saving MAC Protocols for WSNs and Optimization of S-MAC Protocol

    Directory of Open Access Journals (Sweden)

    Simarpreet Kaur

    2012-11-01

    Full Text Available Low power MAC protocols have received a lot of consideration in the last few years because of their influence on the lifetime of wireless sensor networks. Since, sensors typically operate on batteries, replacement of which is often difficult. A lot of work has been done to minimize the energy expenditure and prolong the sensor lifetime through energy efficient designs, across layers. Meanwhile, the sensor network should be able to maintain a certain throughput in order to fulfill the QoS requirements of the end user, and to ensure the constancy of the network. This paper introduces different types of MAC protocols used for WSNs and proposes S‐MAC, a Medium‐Access Control protocol designed for Wireless Sensor Networks. S‐MAC uses a few innovative techniques to reduce energy consumption and support selfconfiguration. A new protocol is suggested to improve the energy efficiency, latency and throughput of existing MAC protocol for WSNs. A modification of the protocol is then proposed to eliminate the need for some nodes to stay awake longer than the other nodes which improves the energy efficiency, latency and throughput and hence increases the life span of a wireless sensor network.

  6. Stratified Sampling to Define Levels of Petrographic Variation in Coal Beds: Examples from Indonesia and New Zealand

    Directory of Open Access Journals (Sweden)

    Tim A. Moore

    2016-01-01

    Full Text Available DOI: 10.17014/ijog.3.1.29-51Stratified sampling of coal seams for petrographic analysis using block samples is a viable alternative to standard methods of channel sampling and particulate pellet mounts. Although petrographic analysis of particulate pellets is employed widely, it is both time consuming and does not allow variation within sampling units to be assessed - an important measure in any study whether it be for paleoenvironmental reconstruction or in obtaining estimates of industrial attributes. Also, samples taken as intact blocks provide additional information, such as texture and botanical affinity that cannot be gained using particulate pellets. Stratified sampling can be employed both on ‘fine’ and ‘coarse’ grained coal units. Fine-grained coals are defined as those coal intervals that do not contain vitrain bands greater than approximately 1 mm in thickness (as measured perpendicular to bedding. In fine-grained coal seams, a reasonable sized block sample (with a polished surface area of ~3 cm2 can be taken that encapsulates the macroscopic variability. However, for coarse-grained coals (vitrain bands >1 mm a different system has to be employed in order to accurately account for the larger particles. Macroscopic point counting of vitrain bands can accurately account for those particles>1 mm within a coal interval. This point counting method is conducted using something as simple as string on a coal face with marked intervals greater than the largest particle expected to be encountered (although new technologies are being developed to capture this type of information digitally. Comparative analyses of particulate pellets and blocks on the same interval show less than 6% variation between the two sample types when blocks are recalculated to include macroscopic counts of vitrain. Therefore even in coarse-grained coals, stratified sampling can be used effectively and representatively.

  7. SR-MAC: A Low Latency MAC Protocol for Multi-Packet Transmissions in Wireless Sensor Networks

    Institute of Scientific and Technical Information of China (English)

    Hong-Wei Tang; Jian-Nong Cao; Xue-Feng Liu; Cai-Xia Sun

    2013-01-01

    Event detection is one of the major applications of wireless sensor networks (WSNs).Most of existing medium access control (MAC) protocols are mainly optimized for the situation under which an event only generates one packet on a single sensor node.When an event generates multiple packets on a single node,the performance of these MAC protocols degrades rapidly.In this paper,we present a new synchronous duty-cycle MAC protocol called SR-MAC for the event detection applications in which multiple packets are generated on a single node.SR-MAC introduces a new scheduling mechanism that reserves few time slots during the SLEEP period for the nodes to transmit multiple packets.By this approach,SR-MAC can schedule multiple packets generated by an event on a single node to be forwarded over multiple hops in one operational cycle without collision.We use event delivery latency (EDL) and event delivery ratio (EDR) to measure the event detection capability of the SR-MAC protocol.Through detailed ns-2 simulation,the results show that SR-MAC can achieve lower EDL,higher EDR and higher network throughput with guaranteed energy efficiency compared with R-MAC,DW-MAC and PR-MAC.

  8. W-MAC: a workload-aware MAC protocol for heterogeneous convergecast in wireless sensor networks.

    Science.gov (United States)

    Xia, Ming; Dong, Yabo; Lu, Dongming

    2011-01-01

    The power consumption and latency of existing MAC protocols for wireless sensor networks (WSNs) are high in heterogeneous convergecast, where each sensor node generates different amounts of data in one convergecast operation. To solve this problem, we present W-MAC, a workload-aware MAC protocol for heterogeneous convergecast in WSNs. A subtree-based iterative cascading scheduling mechanism and a workload-aware time slice allocation mechanism are proposed to minimize the power consumption of nodes, while offering a low data latency. In addition, an efficient schedule adjustment mechanism is provided for adapting to data traffic variation and network topology change. Analytical and simulation results show that the proposed protocol provides a significant energy saving and latency reduction in heterogeneous convergecast, and can effectively support data aggregation to further improve the performance.

  9. Notas sobre dois livros de MacIntyre Notes on two books by MacIntyre

    Directory of Open Access Journals (Sweden)

    Isabel Ribeiro de Oliveira

    2005-04-01

    Full Text Available Os conceitos centrais da teoria da justiça desenvolvida por Alasdair MacIntyre - prática, narrativa e tradição - ocupam o núcleo da análise feita acerca de dois de seus livros: Depois da Virtude e Justiça de Quem? Qual racionalidade?. O artigo considera a relação, em MacIntyre, entre ética e história, virtude e relativismo, bem como apresenta seu conceito do Eu, como corretivos à anomia contemporânea.The central concepts of MacIntyre's approach to justice - practice, narrative and tradition - constitute the main trust of the analysis of two of his books: After Virtue and Whose justice? Which rationality? The article elaborates on the relationship of ethics to history, of virtues to relativism as well as his conception of the self as correctives to the pervasive anomie in contemporary societies.

  10. Defining an appropriate leucoreduction strategy by serial assessment of cytokine levels in platelet concentrates prepared by different methods

    Directory of Open Access Journals (Sweden)

    Daljit Kaur

    2015-01-01

    Full Text Available Background and Objectives: Different methods of platelet concentrate preparations leave behind certain number of residual leukocytes, accounting for most of the febrile nonhemolytic transfusion reactions, especially in multitransfused patients. Various inflammatory cytokines, such as tumor necrosis factor-α (TNF-α, interleukin-1β (IL-1β, and IL-6 are generated during storage and have been implicated for these adverse effects. We have studied the levels of these cytokines and their correlation with leucocyte contents in platelet concentrates prepared by three different methods. Study Design and Methods: Five pools of platelet rich plasma platelet concentrates (PRP-PC and buffy-coat platelet concentrates (BC-PC each were prepared and divided into two halves. One half of the pool was leucofiltered (LF, whereas the other half was stored as such. Ten apheresis units were also included in the study. All the platelet concentrates were assessed for leucocyte load and cytokine content (IL-1β, IL-6, and TNF-α on different days of storage (0, 3, and 5 using Nageotte chamber and commercially available immunoassays respectively. Results: There was a statistically significant rise in cytokine levels (IL-1β, IL-6, and TNF-α in nonleucofiltered (NLF random donor platelet concentrates (RDPs (PRP-PC and BC-PC during storage (day 3 and 5 whereas LF RDP concentrates (PRP-PC and BC-PC and apheresis platelet concentrates (AP-PC did not show any significant rise in cytokine levels (on day 3 and 5 over the baseline values at day 0. Conclusion: This data suggests that although AP-PCs are superior to PRP-PC (NLF and BC-PC (NLF in terms of in vitro quality control parameters and cytokine generation during storage, BC-PC mode of platelet preparation followed by leucofiltration is the best method to store platelets and minimise the cytokine accumulation. This strategy is best suited for transfusion in multitransfused hematooncologic patients, who cannot afford

  11. Relationship of DUI recidivism to moral reasoning, sensation seeking, and MacAndrew alcoholism scores.

    Science.gov (United States)

    Little, G L; Robinson, K D

    1989-12-01

    115 convicted male DUI offenders were treated with Moral Reconation Therapy during their incarceration. Postrelease recidivism status (arrests) was correlated with the pretest, posttest, and change scores on the MacAndrew Alcoholism Scale, Sensation Seeking Scale, Life-purpose scores, and Moral Reasoning scores. Analysis showed that recidivism correlated positively and significantly with the pretest scores on the MacAndrew scale and approached significance with both pre- and posttest scores on the Sensation Seeking Scale. Recidivism status correlated negatively and significantly with scores on the highest levels of moral reasoning (Scale 6 pretest and posttest and Principled Reasoning pretest).

  12. The MacNew Heart Disease health-related quality of life instrument: A summary

    Directory of Open Access Journals (Sweden)

    Guyatt Gordon

    2004-01-01

    Full Text Available Abstract Background The measurement of health, the effects of disease, and the impact of health care include not only an indication of changes in disease frequency and severity but also an estimate of patients' perception of health status before and after treatment. One of the more important developments in health care in the past decade may be the recognition that the patient's perspective is as legitimate and valid as the clinician's in monitoring health care outcomes. This has lead to the development of instruments to quantify the patients' perception of their health status before and after treatment. Methods We review evidence supporting the measurement properties of the MacNew Heart Disease Health-related Quality of Life [MacNew] Questionnaire which was designed to evaluate how daily activities and physical, emotional, and social functioning are affected by coronary heart disease and its treatment. Results Reliability was demonstrated by using internal consistency and the intraclass correlation coefficients for the three domains in the Dutch, English, Farsi, German, and Spanish versions of the MacNew. With internal consistency and intraclass correlation coefficients =>0.73, reliability is high. Validity of the MacNew was examined with factor analysis and three core underlying factors, physical, emotional, and social, were identified, explaining 63.0 – 66.5% of the observed variance and replicated in the translations with psychometric data. Construct validity of the MacNew was further demonstrated by extensive substantiation of the logical relationships, defined a priori, between items and other comparison tools. The MacNew is responsive and sensitive to changes in HRQL following various interventions for patients with heart disease with 11 of 13 effect size statistics >0.80. Taking an average of 10 minutes or less to complete, the respondent-burden for the MacNew is low and its acceptability is demonstrated by response rates of over 90

  13. "What Have We Done for Us Lately?"--Defining Performance and Value at the Individual Clinician Level.

    Science.gov (United States)

    Dobie, Katherine H; Tiwari, Vikram; Sandberg, Warren S

    2015-12-01

    Consolidation in anesthesiology practice and the rest of health care creates pressure to improve the product offered by anesthesia professionals. Anesthesia professionals must offer more than a reliable stream of anesthetized, operated, and recovered patients to remain competitive. By pooling resources and application of leadership effort, large departments and group practices can conduct individual-level value assessments of clinicians. Individual clinicians can be incentivized to improve their personal value proposition. By creating an interlocking program of ongoing assessment, career development coaching and opportunities, as well as compensation, departments and group practices can return value to individual clinicians by curating and accelerating their career and capability development. Copyright © 2015 Elsevier Inc. All rights reserved.

  14. A Review of MAC Scheduling Algorithms in LTE System

    Directory of Open Access Journals (Sweden)

    Satheesh Monikandan B

    2017-06-01

    Full Text Available The recent wireless communication networks rely on the new technology named Long Term Evolution (LTE to offer high data rate real-time (RT traffic with better Quality of Service (QoS for the increasing demand of customer requirement. LTE provide low latency for real-time services with high throughput, with the help of two-level packet retransmission. Hybrid Automatic Repeat Request (HARQ retransmission at the Medium Access Control (MAC layer of LTE networks achieves error-free data transmission. The performance of the LTE networks mainly depends on how effectively this HARQ adopted in the latest communication standard, Universal Mobile Telecommunication System (UMTS. The major challenge in LTE is to balance QoS and fairness among the users. Hence, it is very essential to design a down link scheduling scheme to get the expected service quality to the customers and to utilize the system resources efficiently. This paper provides a comprehensive literature review of LTE MAC layer and six types of QoS/Channel-aware downlink scheduling algorithms designed for this purpose. The contributions of this paper are to identify the gap of knowledge in the downlink scheduling procedure and to point out the future research direction. Based on the comparative study of algorithms taken for the review, this paper is concluded that the EXP Rule scheduler is most suited for LTE networks due to its characteristics of less Packet Loss Ratio (PLR, less Packet Delay (PD, high throughput, fairness and spectral efficiency.

  15. Heterogeneity of the Mac-1 expression on peripheral blood neutrophils in patients with different types of epithelial ovarian cancer.

    Science.gov (United States)

    Bednarska, Katarzyna; Klink, Magdalena; Wilczyński, Jacek R; Szyłło, Krzysztof; Malinowski, Andrzej; Sułowska, Zofia; Nowak, Marek

    2016-02-01

    The expression level of Mac-1 on the surface of neutrophils is an important indicator of neutrophil activation. Under pathological conditions, Mac-1 is believed a key adhesion molecule that facilitates cancer progression and mediates the adhesion of tumour cells to the endothelium of blood vessels. Our previous findings indicated that circulating peripheral blood neutrophils in patients with advanced epithelial ovarian cancer (EOC) expressed enhanced levels of Mac-1, which was functionally associated with an increased adhesive function of neutrophils. The objective of the current study was to analyse whether the value of individual components of the differential white cell count, including the neutrophil and lymphocyte ratios, which are markers of blood neutrophil activation, might be associated with certain types of ovarian cancer. We showed the increase in Mac-1 expression along with a parallel decrease of L-selectin and PSGL-1 on peripheral blood neutrophils of patients with EOC of early and advanced FIGO stages, which indicates an activated state of neutrophils in comparison to neutrophils of individuals without cancer. Despite a significant difference between Mac-1 expression in patients with and without cancer, a dramatic increase in Mac-1 expression was observed in the blood of patients with undifferentiated carcinomas compared with patients with other histological types of EOC. Moreover, the expression level of Mac-1 correlated with the number of neutrophils in patients with serous, endometrioid and undifferentiated EOC. The results of an ROC analysis demonstrated that the patients with the undifferentiated type of EOC form a distinct group with regard to Mac-1 expression on blood neutrophils. The results suggested a diverse biological cadre of immune cells in patients with undifferentiated ovarian carcinomas compared with patients with other histological types of EOC.

  16. Active Learning: A Prerequisite for Language Development in the Mixed Ability Class (MAC of Engineering Students

    Directory of Open Access Journals (Sweden)

    Meenakshi Harraw Verma

    2011-07-01

    Full Text Available Engineering students tend to pay more attention to their core subject classes rather than on an English language class. They all come from different social and academic backgrounds and their knowledge of English language varies from one another. A mixed ability group throws many challenges to an English language teacher teaching to a grown up or rather adult group of learners who always pre-define their interests and needs. The primary and the most important challenge in front of the language teacher teaching engineering students is - how to promote active learning in MAC situation? A language teacher to overcome the problems of a mixed ability classroom and promote active learning needs to adopt a number of strategies. The paper studies the MAC situation in an English language classroom of engineering students and makes an attempt to re-define methods for active learning a prerequisite for language development in an engineering classroom.

  17. An approach to define potential radon emission level maps using indoor radon concentration measurements and radiogeochemical data positive proportion relationships.

    Science.gov (United States)

    Drolet, Jean-Philippe; Martel, Richard; Poulin, Patrick; Dessau, Jean-Claude; Lavoie, Denis; Parent, Michel; Lévesque, Benoît

    2013-10-01

    The aim of this paper is to present the first step of a new approach to make a map of radonprone areas showing different potential radon emission levels in the Quebec province. This map is a tool intended to assist the Quebec government in identifying populations with a higher risk of indoor radon gas exposure. This map of radon-prone areas used available radiogeochemical information for the province of Quebec: (1) Equivalent uranium (eU) concentration from airborne surface gamma-ray surveys; (2) uranium concentration measurements in sediments; and (3) bedrock and surficial geology. Positive proportion relationships (PPR) between each individual criterion and the 1417 available basement radon concentrations were demonstrated. It was also shown that those criteria were reliable indicators of radon-prone areas. The three criteria were discretized into 3, 2 and 2 statistically significant different classes respectively. For each class, statistical heterogeneity was validated by Kruskal-Wallis one way analyses of variance on ranks. Maps of radon-prone areas were traced down for each criterion. Based on this statistical study and on the maps of radon-prone areas in Quebec, 18% of the dwellings located in areas with an equivalent uranium (eU) concentration from airborne surface gamma-ray surveys under 0.75 ppm showed indoor radon concentrations above 150 Bq/m3. This percentage increases to 33% when eU concentrations are between 0.75 ppm and 1.25 ppm and exceeds 40% when eU concentrations are above 1.25 ppm. A uranium concentration in sediments above 20 ppm showed an indoor radon concentration geometric mean of 215 Bq/m3 with more than 69% of the dwellings exceeding 150 Bq/m3 or more than 50% of dwellings exceeding the Canadian radon guideline of 200 Bq/m3. It is also shown that the radon emission potential is higher where a uranium-rich bedrock unit is not covered by a low permeability (silt/clay) surficial deposit.

  18. A case of Mac Tel 2 with an unusual sub macular vitelliform lesion.

    Science.gov (United States)

    Lekha, T; Sarwate, Nikit; Sarwate, Renuka

    2015-01-01

    Observational case report describing the clinical, FFA, OCT and mfERG findings in an elderly female patient with atypical features of macular telangiectasia (Mac Tel 2) RESULTS: A 71-year-old lady was detected to have characteristic features of Mac Tel 2 in the left eye (LE) and a yellowish sub macular vitelliform like lesion in the right eye (RE). FFA showed ill defined hyper fluorescence in the RE and telangiectasia and parafoveal leakage typical of Mac Tel 2 in the LE. On OCT RE had hyper reflective clump of echoes subfoveally with an intact RPE and LE had foveal thinning with hypo reflective intraretinal cavities. mfERG responses were normal in the RE and reduced in the LE. During the course of 3 years LE showed natural progression while RE remained unchanged. Structural and functional evaluation of an unusual sub macular vitelliform lesion seen in association with Mac Tel 2 and its course over a period of 3 years is described. The differentiating features of this lesion from adult onset foveomacular vitelliform dystrophy (AFMD) are discussed.

  19. [Materials for the substantiation of the biological MAC of benzene].

    Science.gov (United States)

    Ulanova, I P; Avilova, G G; Karpukhina, E A; Karimova, L K; Boĭko, V I; Makar'eva, L M

    1990-09-01

    Relatively great amount of benzene-originated phenol, the presence of a definite relationship between phenol amount in the urine and benzene content in the air indicate that it is reasonable to use a phenol sample as an exposure test. To determine the intensity of benzene exposure, data on phenol content in the urine of people working at some big-tonnage enterprises has been analyzed. On the basis of the national and foreign literature data on the correlation between the phenol urine concentration and the level of benzene exposure a regression equation was deduced, which has made it possible to calculate phenol content in the urine on the level of average working day benzene concentration adopted in the USSR. This value equals 15 mg/l, which was proposed as a biological benzene MAC.

  20. Monitored Anaesthesia Care (MAC in antalgic surgery

    Directory of Open Access Journals (Sweden)

    Giovanni Maria Pisanu

    2011-09-01

    Full Text Available The use of surgical techniques for pain relief in the treatment of chronic-persistent pain unresponsive to drug therapy is experiencing a growing spread application in algology. These techniques have set themselves the goal of removing the pain after treatment. Therefore, not always, percutaneous or open procedures are carried out with due precaution necessary to alleviate the patient discomfort and suffering during the surgical intervention. We present our personal experience in the use of this technique Monitored Anaesthesia Care (MAC for patients undergoing surgical treatment of pain management at our Regional Center of Pain Management.

  1. One of the First Portable Macs

    CERN Multimedia

    1989-01-01

    It was one of the first portable macs released. The Portable had many new advances in mobile computing : The display was crispy clear, and looked beautiful when used in daylight ; The Portable came with a Lead-acid gel/cell battery that could run a anywhere from 6 -12 hours ; It supported to internal hard drives, and an external one. The reaction to the laptop was weak because it was slow, it had no capacity for expansion, it weighed heavily, its price was expensive. It has been stayed 1 year and half on the market.

  2. Energy Efficient MAC for Wireless Sensor Networks

    Directory of Open Access Journals (Sweden)

    Pekka KOSKELA

    2010-10-01

    Full Text Available This paper considers an overlay solution for asynchronous Medium Access Control (MAC protocols in a duty-cycled wireless sensor network (WSN. The solution extends sleeping times and corrects time drift when the sampling rate is low. The sleeping time is adjusted according to the requisite data sampling rate and the delay requirements of the prevailing application. This and the time drift correction considerably reduced idle listening and thus also decreased power consumption. When the power consumption is reduced, the life of wireless sensor nodes extends.

  3. Implementation of MAC by using Modified Vedic Multiplier

    OpenAIRE

    2013-01-01

    Multiplier Accumulator Unit (MAC) is a part of Digital Signal Processors. The speed of MAC depends on the speed of multiplier. So by using an efficient Vedic multiplier which excels in terms of speed, power and area, the performance of MAC can be increased. For this fast method of multiplication based on ancient Indian Vedic mathematics is proposed in this paper. Among various method of multiplication in Vedic mathematics, Urdhva Tiryagbhyam is used and the multiplication is for 32 X 32 bits....

  4. Essential Mac OS X panther server administration integrating Mac OS X server into heterogeneous networks

    CERN Document Server

    Bartosh, Michael

    2004-01-01

    If you've ever wondered how to safely manipulate Mac OS X Panther Server's many underlying configuration files or needed to explain AFP permission mapping--this book's for you. From the command line to Apple's graphical tools, the book provides insight into this powerful server software. Topics covered include installation, deployment, server management, web application services, data gathering, and more

  5. APC-MAC/TA: Adaptive Power Controlled MAC Protocol with Traffic Awareness for Wireless Sensor Networks

    Science.gov (United States)

    Woo, Seok; Kim, Kiseon

    In this paper, we propose an adaptive power controlled MAC protocol with a traffic-aware scheme specifically designed to reduce both energy and latency in wireless sensor networks. Typically, existing MAC protocols for sensor networks sacrifice latency performance for node energy efficiency. However, some sensor applications for emergencies require rather fast transmissions of sensed data, where we need to consider both energy and latency together. The proposed MAC protocol includes two novel ideas: one is a transmission power control scheme for improving latency in high traffic loads, and the other is a traffic-aware scheme to save more energy in low traffic loads. The transmission power control scheme increases channel utilization by mitigating interference between nodes, and the traffic-aware scheme allows nodes to sleep to reduce idle energy consumption when there are no traffic loads in a network. Simulation results show that the proposed protocol significantly reduces the latency as well as the energy consumption compared to the S-MAC protocol specifically for a large transmission power of nodes and low network traffic.

  6. Mac OS X Snow Leopard Server For Dummies

    CERN Document Server

    Rizzo, John

    2009-01-01

    Making Everything Easier!. Mac OS® X Snow Leopard Server for Dummies. Learn to::;. Set up and configure a Mac network with Snow Leopard Server;. Administer, secure, and troubleshoot the network;. Incorporate a Mac subnet into a Windows Active Directory® domain;. Take advantage of Unix® power and security. John Rizzo. Want to set up and administer a network even if you don't have an IT department? Read on!. Like everything Mac, Snow Leopard Server was designed to be easy to set up and use. Still, there are so many options and features that this book will save you heaps of time and effort. It wa

  7. Energy-efficient MAC protocols for Wireless Sensor Networks

    Institute of Scientific and Technical Information of China (English)

    Li De-liang; Peng Fei

    2009-01-01

    Designing energy-efficient Medium Access Control (MAC) protocols has a significant influence on the energy performance of wireless sensor network (WSN). In this paper we present a survey of the recent typical MAC protocols regarding energy efficiency for WSN. According to channel access policies, we classify these protocols into four categories: contention-based, TDMA-based, hybrid, and cross layer protocols, in which the advantages and disadvantages in each class of MAC protocols are discussed. Finally, we point out open research issues that need to carry on to achieve high energy efficiency for the design of MAC protocols in WSN.

  8. Study on intracellular trafficking of Mac-1 by direct visualization

    Institute of Scientific and Technical Information of China (English)

    YAN Ming; MAO Jifang; WEI Yi; ZHONG Jigen; YANG Shengsheng; XU Renbao

    2004-01-01

    Previously, we constructed DNA vectors containing cDNA of Mac-1 subunits (CD11b or CD18b) fused with fluorescence protein (FP). cDNA fragments and the DNA constructs were then transfected into CHO cells (as CHO-Mac-1-FP). The structure and function of Mac-1-FP obtained from the CHO-Mac-1-FP cells are nearly identical to that expressed in wild type leukocytes. In the present study, the intracellular trafficking of Mac-1 was visualized directly by monitoring the fluorescent intensities of YFP-CD18 and PE-conjugated monoclonal antibody against CD11b under a confocal microscope in CHO-Mac-1-FP cells. The results indicate that: (ⅰ) although Mac-1 was not detected in the cell membrane at resting state, it had been translocated and clustered into the cell membrane by 1 h and internalized 2 h after PMA stimulation, at which point the fluorescence intensity began to diminish gradually, probably due to partial degradation of Mac-1. The fluorescence of CD18 and CD11b reappeared on the cell membrane 1 h after re-treatment with PMA, suggesting the recycling of non-degraded Mac-1. (ⅱ) The adhesion rate of CHO-Mac-1-FP to magnetic beads coupled ICAM-1 increased within 4 h after their initial interaction, accompanied by the clustering of Mac-1-FP. After 8 h,the adhesion rate declined and fluorescence also decreased simultaneously. The pattern of change in fluorescence in CHO-Mac-1-FP cells elicited by ICAM-1 beads was similar to that elicited by PMA, suggesting that endocytosis and degradation of Mac-1 occurred after the interaction with ICAM-1. Thus, we conclude that the intracellular trafficking of Mac-1 after activation is associated with membrane translocation, endocytosis, degradation and recycling. These changes are in parallel with the adhesion of CHO-Mac-1-FP cells with ICAM-1, and may be involved in the adhesion and detachment of leukocytes. The detachment of leukocytes may be caused by endocytosis of Mac-1.

  9. An Energy Efficient Analysis of S-MAC And H-MAC Protocols for Wireless Sensor Networks

    Directory of Open Access Journals (Sweden)

    P.T.Kalaivaani

    2013-04-01

    Full Text Available Wireless Sensor Networks (WSNs is an interesting topic to the researchers because of its variousapplications. The applications are health monitoring and environmental monitoring, Industrial ProcessMonitoring, Target detection, Target tracking, Energy Efficiency, Disaster Management and MilitarySecurity Systems. The wireless medium requires highly optimized medium Access Protocols to avoidinterferences. Limited resources have driven the research towards energy consumption of MACfunctionalities. Two Medium Access Control (MAC protocol performances are analyzed by using the MAClayer frame work for wireless sensor networks. In this paper an energy efficient analysis of S-MAC and HMACprotocols for wireless sensor networks is proposed with spatial correlation concept. Two MACprotocols such as Sensor MAC (S-MAC and Hybrid MAC (H-MAC protocols are proposed to analyze theperformance of Wireless Sensor Network using four different Parameters such as End to End delay, PacketDelivery Ratio, Packet Drop Rate and Energy Consumption. Performance analysis is carried out by usingthe simulation tool NS2.

  10. TreeMAC: Localized TDMA MAC protocol for real-time high-data-rate sensor networks

    Science.gov (United States)

    Song, W.-Z.; Huang, R.; Shirazi, B.; LaHusen, R.

    2009-01-01

    Earlier sensor network MAC protocols focus on energy conservation in low-duty cycle applications, while some recent applications involve real-time high-data-rate signals. This motivates us to design an innovative localized TDMA MAC protocol to achieve high throughput and low congestion in data collection sensor networks, besides energy conservation. TreeMAC divides a time cycle into frames and each frame into slots. A parent node determines the children's frame assignment based on their relative bandwidth demand, and each node calculates its own slot assignment based on its hop-count to the sink. This innovative 2-dimensional frame-slot assignment algorithm has the following nice theory properties. First, given any node, at any time slot, there is at most one active sender in its neighborhood (including itself). Second, the packet scheduling with TreeMAC is bufferless, which therefore minimizes the probability of network congestion. Third, the data throughput to the gateway is at least 1/3 of the optimum assuming reliable links. Our experiments on a 24-node testbed show that TreeMAC protocol significantly improves network throughput, fairness, and energy efficiency compared to TinyOS's default CSMA MAC protocol and a recent TDMA MAC protocol Funneling-MAC. Partial results of this paper were published in Song, Huang, Shirazi and Lahusen [W.-Z. Song, R. Huang, B. Shirazi, and R. Lahusen, TreeMAC: Localized TDMA MAC protocol for high-throughput and fairness in sensor networks, in: The 7th Annual IEEE International Conference on Pervasive Computing and Communications, PerCom, March 2009]. Our new contributions include analyses of the performance of TreeMAC from various aspects. We also present more implementation detail and evaluate TreeMAC from other aspects. ?? 2009 Elsevier B.V.

  11. Define Project

    DEFF Research Database (Denmark)

    Munk-Madsen, Andreas

    2005-01-01

    "Project" is a key concept in IS management. The word is frequently used in textbooks and standards. Yet we seldom find a precise definition of the concept. This paper discusses how to define the concept of a project. The proposed definition covers both heavily formalized projects and informally...... organized, agile projects. Based on the proposed definition popular existing definitions are discussed....

  12. Can we define a tolerable level of risk in food allergy? Report from a EuroPrevall/UK Food Standards Agency workshop.

    Science.gov (United States)

    Madsen, C B; Hattersley, S; Allen, K J; Beyer, K; Chan, C-H; Godefroy, S B; Hodgson, R; Mills, E N C; Muñoz-Furlong, A; Schnadt, S; Ward, R; Wickman, M; Crevel, R

    2012-01-01

    There is an emerging consensus that, as with other risks in society, zero risk for food-allergic people is not a realistic or attainable option. Food allergy challenge data and new risk assessment methods offer the opportunity to develop quantitative limits for unintended allergenic ingredients which can be used in risk-based approaches. However, a prerequisite to their application is defining a tolerable level of risk. This requires a value judgement and is ultimately a 'societal' decision that has to involve all relevant stakeholders. The aim of the workshop was to bring together key representatives from the stakeholders (regulators, food industry, clinical researchers and patients), and for the first time ever discuss the definition of a tolerable level of risk with regard to allergic reactions to food. The discussions revealed a consensus that zero risk was not a realistic option and that it is essential to address the current lack of agreed action levels for cross-contamination with allergens if food allergen management practice is to be improved. The discussions also indicated that it was difficult to define and quantify a tolerable level of risk, although both the clinical and the industry groups tried to do so. A consensus emerged that doing nothing was not a viable option, and there was a strong desire to take action to improve the current situation. Two concrete actions were suggested: (1) Action levels should be derived from the data currently available. Different scenarios should be examined and further developed in an iterative process. On the basis of this work, a tolerable level of risk should be proposed. (2) 'One-dose' clinical trial with a low challenge dose should be performed in multiple centres to provide additional information about the general applicability of dose-distribution models and help validate the threshold levels derived. © 2011 Blackwell Publishing Ltd.

  13. 42 CFR 405.1122 - What evidence may be submitted to the MAC.

    Science.gov (United States)

    2010-10-01

    ... 42 Public Health 2 2010-10-01 2010-10-01 false What evidence may be submitted to the MAC. 405.1122... Council Review § 405.1122 What evidence may be submitted to the MAC. (a) Appeal before the MAC on request for review of ALJ's decision. (1) If the MAC is reviewing an ALJ's decision, the MAC limits its review...

  14. 42 CFR 423.2122 - What evidence may be submitted to the MAC.

    Science.gov (United States)

    2010-10-01

    ... 42 Public Health 3 2010-10-01 2010-10-01 false What evidence may be submitted to the MAC. 423.2122..., MAC review, and Judicial Review § 423.2122 What evidence may be submitted to the MAC. (a) Appeal before the MAC on request for review of ALJ's decision. (1) If the MAC is reviewing an ALJ's decision...

  15. The Level of Oxidative Neutrophil Response When Determining Endotoxin Activity Assay: A New Biomarker for Defining the Indications and Effectiveness of Intensive Care in Patients with Sepsis

    Directory of Open Access Journals (Sweden)

    Michael Yaroustovsky

    2017-01-01

    Full Text Available Background. To analyse the clinical informativity of the neutrophil oxidative response level (“Response” during an Endotoxin Activity Assay (EAA as a new biomarker defining the indications and effectiveness of intensive care in cardiac surgical patients with septic complications. Methods. Blood samples were taken from 198 adult patients who were admitted to the ICU after cardiac surgery (SIRS: 34, MODS: 36, and sepsis: 128. The composite of laboratory studies included CRP, PCT, EAA with “Response” level, and presepsin. Results. 83% of patients had a “normal” neutrophil response, 12% of patients had a low neutrophil response, and 5% of patients had a critically low neutrophil response. Patients with critically low responses had the lowest values of the EAA and the highest concentrations of PSP and D-dimer (p 0.5 has a negative predictive value; the EAA < 0.6 at “Response” < 0.5 may indicate a high level of endotoxaemia.

  16. Selective depletion of Mac-1-expressing microglia in rat subventricular zone does not alter neurogenic response early after stroke.

    Science.gov (United States)

    Heldmann, Ursula; Mine, Yutaka; Kokaia, Zaal; Ekdahl, Christine T; Lindvall, Olle

    2011-06-01

    Ischemic stroke induces migration of newly formed neuroblasts, generated by neural stem cells in the adult rat subventricular zone (SVZ), towards the injured striatum where they differentiate into mature neurons. Stroke also leads to accumulation of microglia in the SVZ but their role for neurogenesis is unclear. Here we developed a method for selective depletion of the macrophage antigen complex-1 (Mac-1)-expressing microglia population in the SVZ by intraventricular injection of the immunotoxin Mac-1-saporin in rats. We found that the vast majority of Mac-1+ cells were Iba-1+ microglia. The Mac-1+ population was heterogeneous and included both a small proliferative pool of cells, which was not affected by middle cerebral artery occlusion (MCAO), and a larger subpopulation that changed morphologically into a semi-activated state in response to the insult. This subpopulation did not increase its expression of the phagocytic marker ED1 but exhibited high levels of triggering receptor expressed on myeloid cells-2 (TREM-2), associated with alternative microglia activation. A minor portion of the SVZ Mac-1+ cells originated from the blood early after stroke, but this macrophage population became much more substantial at later stages. Almost 80% reduction of Mac-1-expressing microglia, caused by Mac-1 saporin delivered just before and at 1 week after MCAO, did not alter the numbers of newly formed neuroblasts in the striatum or their migratory distance. These findings indicate that the Mac-1-expressing microglia in the SVZ do not play a major role either for the number of neuroblasts which exit the SVZ or their migration in the striatum early following stroke.

  17. Delay Analysis of an Enhancing IEEE 802.11 Point Coordination Function MAC Protocol

    Directory of Open Access Journals (Sweden)

    Zheng Guan

    2014-05-01

    Full Text Available The widespread use of multimedia networking applications has brought more requirements to the network, creating a need for end-to-end Quality of Service (QoS. The contention-free Point Coordination Function (PCF with Round Robin scheme, where the Access Point controls all transmissions based on a polling mechanism, is defined in IEEE 802.11 standard to provide QoS service. This network suffers from inefficiency in the delay sensitive traffic and makes. It is difficult to provide priority-differentiated service. In this paper, a useful enhance mechanism is derived from a two-level-polling model with a parallel scheme between the polling and switch over processes. We consider two different polling schemes according to station classify: key station and normal station. This mechanism allows for a delay guarantee as well as priority service. An analytical is developed for evaluating the queuing length for the station and waiting time for the packets at nodes. Based on this model, we achieve several closed-form expressions for mean cycle time, mean queue length and mean waiting time. To verify the correctness of our analytical model, we also develop a simulator for the 802.11 PCF MAC. The simulation results well match the analytical results.

  18. Mycobacterium avium complex (MAC) Immune Reconstitution Syndrome (IRIS) With Reduced Susceptibility to Ethambutol in an HIV-Infected Patient.

    Science.gov (United States)

    Adams, Immaculata B; Schafer, Jason J; Roberts, Amity L; Short, William R

    2014-09-01

    To describe a case of Mycobacterium avium complex (MAC) lymphadenitis complicated by immune reconstitution syndrome (IRIS) and reduced susceptibility to ethambutol. A 24-year-old man was diagnosed in October 2012 with advanced HIV infection upon hospitalization for multiple opportunistic infections (OIs). Within 5 months of starting antiretroviral therapy, the patient developed significant cervical lymphadenopathy concerning for MAC/IRIS. Acid-fast bacilli were detected in the primary lymph node biopsy smear, and culture results confirmed the presence of MAC. Susceptibility testing revealed an organism susceptible to azithromycin, with an elevated minimum inhibitory concentration (MIC) to ethambutol (8 µg/mL). Currently, there is no interpretation for an ethambutol MIC of 8 µg/mL for MAC. A review of the primary literature revealed the possibility of decreased ethambutol susceptibility when the MIC is above 1 µg/mL, and therefore, therapy was replaced by rifabutin in combination with azithromycin. Current guidelines recommend a 2-drug regimen for the treatment of MAC, specifically a macrolide plus ethambutol. Guidelines also emphasize MAC susceptibility testing for macrolides only. Susceptibility results from this patient's biopsy prompted an evaluation of the effectiveness of his antimycobacterial regimen. Reduced ethambutol susceptibility in this patient triggered a search of the primary literature that resulted in the decision to replace ethambutol with rifabutin. Additional clinical trials are needed to define susceptibility breakpoints for ethambutol and other antimycobacterial agents used for MAC infection treatment and to direct clinical decisions when elevated MICs to primary agents are identified. © The Author(s) 2014.

  19. Influence of prior determination of baseline minimum alveolar concentration (MAC) of isoflurane on the effect of ketamine on MAC in dogs.

    Science.gov (United States)

    Gianotti, Giacomo; Valverde, Alexander; Johnson, Ron; Sinclair, Melissa; Gibson, Thomas; Dyson, Doris H

    2014-07-01

    The objective of this study was to determine if prior measurement of the minimum alveolar concentration (MAC) of isoflurane influences the effect of ketamine on the MAC of isoflurane in dogs. Eight mixed-breed dogs were studied on 2 occasions. Anesthesia was induced and maintained using isoflurane. In group 1 the effect of ketamine on isoflurane MAC was determined after initially finding the baseline isoflurane MAC. In group 2, the effect of ketamine on isoflurane MAC was determined without previous measure of the baseline isoflurane MAC. In both groups, MAC was determined again 30 min after stopping the CRI of ketamine. Plasma ketamine concentrations were measured during MAC determinations. In group 1, baseline MAC (mean ± SD: 1.18 ± 0.14%) was decreased by ketamine (0.88 ± 0.14%; P MAC after stopping ketamine was similar (1.09 ± 0.16%) to baseline MAC and higher than with ketamine (P MAC with ketamine (0.79 ± 0.11%) was also increased after stopping ketamine (1.10 ± 0.17%; P MAC values with ketamine were different between groups (P MAC determination. The MAC of isoflurane during the CRI of ketamine yielded different results when methods of same day (group-1) versus separate days (group-2) are used, despite similar plasma ketamine concentrations with both methods. However, because the magnitude of this difference was less than 10%, either method of determining MAC is deemed acceptable for research purposes.

  20. On the orthogonality of the MacDonald s functions

    Energy Technology Data Exchange (ETDEWEB)

    Passian, Ali [ORNL; Simpson, Henry [University of Tennessee, Knoxville (UTK); Koucheckian, Sherwin [University of South Florida, Tampa; Yakubovich, Semyon [University of Porto, Portugal

    2009-01-01

    A proof of an orthogonality relation for the MacDonald's functions with identical arguments but unequal complex lower indices is presented. The orthogonality is derived first via a heuristic approach based on the Mehler-Fock integral transform of the MacDonald's functions, and then proved rigorously using a polynomial approximation procedure.

  1. SuperMacLang: Development of an Authoring System.

    Science.gov (United States)

    Frommer, Judith; Foelsche, Otmar K. E.

    1999-01-01

    Describes the development of "SuperMacLang, the 1990s version of the MacLang authoring system. An analysis of various features of the program explains the ways in which certain aspects of collaboration and funding affected developer and programming decisions. (Author/VWL)

  2. Steven MacCall: Winner of LJ's 2010 Teaching Award

    Science.gov (United States)

    Berry, John N., III

    2010-01-01

    This article profiles Steven L. MacCall, winner of "Library Journal's" 2010 Teaching Award. An associate professor at the School of Library and Information Studies (SLIS) at the University of Alabama, Tuscaloosa, MacCall was nominated by Kathie Popadin, known as "Kpop" to the members of her cohort in the online MLIS program at SLIS. Sixteen of…

  3. MAC of xenon and halothane in rhesus monkeys.

    Science.gov (United States)

    Whitehurst, S L; Nemoto, E M; Yao, L; Yonas, H

    1994-10-01

    Local cerebral blood flow (LCBF) maps produced by 33% xenon-enhanced computed tomographic scanning (Xe/CT LCBF) are useful in the clinical diagnosis and management of patients with cerebrovascular disorders. However, observations in humans that 25-35% xenon (Xe) inhalation increases cerebral blood flow (CBF) have raised concerns that Xe/CT LCBF measurements may be inaccurate and that Xe inhalation may be hazardous in patients with decreased intracranial compliance. In contrast, 33% Xe does not increase CBF in rhesus monkeys. To determine whether this interspecies difference in the effect of Xe on CBF correlates with an interspecies difference in the anesthetic potency of Xe, we measured the minimum alveolar concentration (MAC) of Xe preventing movement to a tail-clamp stimulus in rhesus monkeys. Using a standard protocol for the determination of MAC in animals, we first measured the MAC of halothane (n = 5), and then used a combination of halothane and Xe to measure the MAC of Xe (n = 7). The halothane MAC was 0.99 +/- 0.12% (M +/- SD), and the Xe MAC was 98 +/- 15%. These results suggest that the MAC of Xe in rhesus monkeys is higher than the reported human Xe MAC value of 71%. Thus the absence of an effect of 33% Xe on CBF in the rhesus monkey may be related to its lower anesthetic potency.

  4. Intel-Based Mac Computers Improve Teaching and Learning

    Science.gov (United States)

    Technology & Learning, 2007

    2007-01-01

    Today, Mac computers offer schools an easy and powerful way to engage students in learning, foster 21st century skills and leverage existing software assets. Innovative software and hardware built into the Mac allows students to demonstrate their individual strengths--empowering them to be creators of content, rather than just consumers. Judging…

  5. Intel-Based Mac Computers Improve Teaching and Learning

    Science.gov (United States)

    Technology & Learning, 2007

    2007-01-01

    Today, Mac computers offer schools an easy and powerful way to engage students in learning, foster 21st century skills and leverage existing software assets. Innovative software and hardware built into the Mac allows students to demonstrate their individual strengths--empowering them to be creators of content, rather than just consumers. Judging…

  6. Multi-channel MAC Protocol in Cognitive Radio Networks

    Directory of Open Access Journals (Sweden)

    Yongli Sun

    2013-11-01

    Full Text Available Since cognitive wireless network (CRN has the characteristic of secondary use, it can enable the device to dynamically access available spectrum without interference to primary users (PUs, which can effectively alleviate contradiction between the lack of spectrum resources and the growing demand for wireless access. However, Medium Access Control (MAC protocol as CRN core components, can achieve competition access of the licensed spectrum and coordination control, which will maximize spectrum utilization efficiency and network throughput. The contribution of this survey is threefold. First, we analyze the characteristics of the existed multi- channel MAC protocol in CRN; Second, according to the different ways of spectrum access in CRNs, the multi-channel MAC protocols are classified into time-slotted based MAC protocol, control channel based MAC protocol and hybrid MAC protocol, and the paper emphatically analyzed the advantages and disadvantages of these multi-channel MAC protocols; Finally, the paper explores the difficulties and the challenges of multi-channel MAC protocols design in cognitive wireless network.

  7. Steven MacCall: Winner of LJ's 2010 Teaching Award

    Science.gov (United States)

    Berry, John N., III

    2010-01-01

    This article profiles Steven L. MacCall, winner of "Library Journal's" 2010 Teaching Award. An associate professor at the School of Library and Information Studies (SLIS) at the University of Alabama, Tuscaloosa, MacCall was nominated by Kathie Popadin, known as "Kpop" to the members of her cohort in the online MLIS program at SLIS. Sixteen of…

  8. A Sensing Error Aware MAC Protocol for Cognitive Radio Networks

    CERN Document Server

    Hu, Donglin

    2011-01-01

    Cognitive radios (CR) are intelligent radio devices that can sense the radio environment and adapt to changes in the radio environment. Spectrum sensing and spectrum access are the two key CR functions. In this paper, we present a spectrum sensing error aware MAC protocol for a CR network collocated with multiple primary networks. We explicitly consider both types of sensing errors in the CR MAC design, since such errors are inevitable for practical spectrum sensors and more important, such errors could have significant impact on the performance of the CR MAC protocol. Two spectrum sensing polices are presented, with which secondary users collaboratively sense the licensed channels. The sensing policies are then incorporated into p-Persistent CSMA to coordinate opportunistic spectrum access for CR network users. We present an analysis of the interference and throughput performance of the proposed CR MAC, and find the analysis highly accurate in our simulation studies. The proposed sensing error aware CR MAC p...

  9. McCay ("Mac") Vernon (1928-2013).

    Science.gov (United States)

    Sherman, William A

    2014-09-01

    McCay ("Mac") Vernon, the founding and preeminent psychologist in the field of deafness. Mac was born at Walter Reed Hospital in Washington, DC, into a military family on October 14, 1928 and died on August 28, 2013, at the age of 84. Prior to Mac, research and clinical direction in the field were sparse. Mac became the icon for psychological services for deaf people, and his work extended into the education of deaf children, forensic and ethical practices with the deaf, and public understanding of deafness as a disability and of deaf persons as a psychosocial minority group. Mac will also be remembered for his sharp intellect, good humor, compassion, and advocacy for those who are misunderstood.

  10. Isoflurane and sevoflurane decrease entropy indices more than halothane at equal MAC values.

    Science.gov (United States)

    Prabhakar, Hemanshu; Ali, Zulfiqar; Bithal, Parmod K; Rath, Girija P; Singh, Deepak; Dash, Hari H

    2009-01-01

    Recently, bispectral index (BIS) values were demonstrated to be different for various anesthetics as a result of differential effects on electroencephalographic (EEG) signals. Entropy is similar to the BIS monitor, as both process raw EEG to derive a number. We hypothesized that entropy may also be anesthetic agent-specific. Thirty adult patients undergoing spinal surgery were randomized to receive halothane, isoflurane, or sevoflurane. Entropy indices were recorded at various minimum alveolar concentration (MAC) values-0.5, 0.75, 1.0 and 1.5-both during wash-in and wash-out of the agent. Heart rate (HR), mean arterial blood pressure (MAP), response entropy (RE), and state entropy (SE) were noted. Statistical analysis was done using a one-way analysis-ofvariance test. P values less than 0.05 were considered significant. Ten patients in each group completed the study. The demographics and baseline values of HR, MAP, RE, and SE were comparable in all three groups. During the study period, for a given MAC value, both RE and SE remained low in the isoflurane and sevoflurane groups compared to the halothane group. For a given MAC, the RE and SE were comparable during wash-in and wash-out phases. Halothane produced higher entropy values as compared to isoflurane and sevoflurane at equivalent MAC levels.

  11. Alasdair MacIntyre, joven lector de Freud

    Directory of Open Access Journals (Sweden)

    Ramis Barceló, Rafael

    2010-06-01

    Full Text Available This article tries to show the reading of Freud that MacIntyre made from 1955 to 1970. For this purpose, it summarizes the ideas of MacIntyre in the intellectual context, mainly the use of philosophical ideas of Freud against the Enlightenment project. MacIntyre criticises Marxist interpreters and the mixing between Marx and Freud. MacIntyre uses the philosophical ideas of Freud for answering two problems on determinism: the links between determinism and reasons for action and determinism and Marxism. The main conclusion is that MacIntyre used Freud in his own advantage: as an ally in the criticism of the Enlightenment.

    Este artículo trata de mostrar la lectura que MacIntyre hizo de Freud desde 1955 hasta 1970. Con este fin, se resumen las ideas de MacIntyre en el contexto intelectual, principalmente el uso de las ideas filosóficas de Freud contra el proyecto de la Ilustración. MacIntyre critica a los intérpretes de Marx y a la mezcla entre Marx y Freud. MacIntyre usa las ideas filosóficas de Freud para contestar dos problemas sobre el determinismo: los vínculos entre el determinismo y las razones para la acción y el determinismo y el marxismo. La conclusión principal es que MacIntyre usó a Freud en su propio beneficio: como un aliado en la crítica de la Ilustración.

  12. TreeMAC: Localized TDMA MAC protocol for real-time high-data-rate sensor networks

    Science.gov (United States)

    Song, W.-Z.; Huang, R.; Shirazi, B.; Husent, R.L.

    2009-01-01

    Earlier sensor network MAC protocols focus on energy conservation in low-duty cycle applications, while some recent applications involve real-time high-data-rate signals. This motivates us to design an innovative localized TDMA MAC protocol to achieve high throughput and low congestion in data collection sensor networks, besides energy conservation. TreeMAC divides a time cycle into frames and frame into slots. Parent determines children's frame assigmnent based on their relative bandwidth demand, and each node calculates its own slot assignment based on its hop-count to the sink. This innovative 2-dimensional frame-slot assignment algorithm has the following nice theory properties. Firstly, given any node, at any time slot, there is at most one active sender in its neighborhood (includ ing itself). Secondly, the packet scheduling with TreelMAC is bufferless, which therefore minimizes the probability of network congestion. Thirdly, the data throughput to gateway is at least 1/3 of the optimum assuming reliable links. Our experiments on a 24 node test bed demonstrate that TreeMAC protocol significantly improves network throughput and energy efficiency, by comparing to the TinyOS's default CSMA MAC protocol and a recent TDMA MAC protocol Funneling-MAC[8]. ?? 2009 IEEE.

  13. TR-MAC: an energy-efficient MAC protocol exploiting transmitted reference modulation for wireless sensor networks

    NARCIS (Netherlands)

    Morshed, S.; Heijenk, Geert

    2014-01-01

    The medium access control (MAC) protocol determines the energy consumption of a wireless sensor node by specifying the listening, transmitting or sleeping time. Therefore MAC protocols play an important role in minimizing the overall energy consumption in a typical wireless sensor network (WSN).

  14. TR-MAC: an energy-efficient MAC protocol exploiting transmitted reference modulation for wireless sensor networks

    NARCIS (Netherlands)

    Morshed, Sarwar; Heijenk, Geert

    2014-01-01

    The medium access control (MAC) protocol determines the energy consumption of a wireless sensor node by specifying the listening, transmitting or sleeping time. Therefore MAC protocols play an important role in minimizing the overall energy consumption in a typical wireless sensor network (WSN). Usi

  15. Inflammation, but not recruitment, of adipose tissue macrophages requires signalling through Mac-1 (CD11b/CD18) in diet-induced obesity (DIO).

    Science.gov (United States)

    Wolf, Dennis; Bukosza, Nora; Engel, David; Poggi, Marjorie; Jehle, Felix; Anto Michel, Nathaly; Chen, Yung-Chih; Colberg, Christian; Hoppe, Natalie; Dufner, Bianca; Boon, Louis; Blankenbach, Hermann; Hilgendorf, Ingo; von Zur Muhlen, Constantin; Reinöhl, Jochen; Sommer, Björn; Marchini, Timoteo; Febbraio, Mark A; Weber, Christian; Bode, Christoph; Peter, Karlheinz; Lutgens, Esther; Zirlik, Andreas

    2017-01-26

    Cell accumulation is a prerequisite for adipose tissue inflammation. The leukocyte integrin Mac-1 (CD11b/CD18, αMβ2) is a classic adhesion receptor critically regulating inflammatory cell recruitment. Here, we tested the hypothesis that a genetic deficiency and a therapeutic modulation of Mac-1 regulate adipose tissue inflammation in a mouse model of diet-induced obesity (DIO). C57Bl6/J mice genetically deficient (Mac-1(-/-)) or competent for Mac-1 (WT) consumed a high fat diet for 20 weeks. Surprisingly, Mac-1(-/-) mice presented with increased diet-induced weight gain, decreased insulin sensitivity in skeletal muscle and in the liver in insulin-clamps, insulin secretion deficiency and elevated glucose levels in fasting animals, and dyslipidaemia. Unexpectedly, accumulation of adipose tissue macrophages (ATMs) was unaffected, while gene expression indicated less inflamed adipose tissue and macrophages in Mac-1(-/-) mice. In contrast, inflammatory gene expression at distant locations, such as in skeletal muscle, was not changed. Treatment of ATMs with an agonistic anti-Mac-1 antibody, M1/70, induced pro-inflammatory genes in cell culture. In vivo, treatment with M1/70 induced a hyper-inflammatory phenotype with increased expression of IL-6 and MCP-1, whereas accumulation of ATMs did not change. Finally, inhibition of Mac-1's adhesive interaction to CD40L by the peptide inhibitor cM7 did not affect myeloid cell accumulation in adipose tissue. We present the surprising finding that adhesive properties of the leukocyte integrin Mac-1 are not required for macrophage accumulation in adipose tissue. Instead, Mac-1 modulates inflammatory gene expression in macrophages. These findings question the net effect of integrin blockade in cardio-metabolic disease.

  16. Effect of epidural and intravenous use of the neurokinin-1 (NK-1) receptor antagonist maropitant on the sevoflurane minimum alveolar concentration (MAC) in dogs.

    Science.gov (United States)

    Alvillar, Brittany M; Boscan, Pedro; Mama, Khursheed R; Ferreira, Tatiana H; Congdon, Jonathan; Twedt, David C

    2012-03-01

    To determine the effect of maropitant, an NK-1 receptor antagonist on the minimum alveolar concentration (MAC) of sevoflurane after intravenous and epidural administration to dogs. Prospective experimental study. Seven, adult, spayed-female dogs (24.8 ± 1.9 kg). Each dog was anesthetized twice with sevoflurane in oxygen, with at least 10 days separating the anesthetic events. The minimum alveolar concentration (MAC) of sevoflurane was determined using the tail-clamp technique. During the first anesthetic event, the MAC of sevoflurane was determined initially and again after intravenous administration of maropitant (5 mg kg(-1)) and an infusion (150 μg kg(-1) hour(-1)). During the second anesthetic event, an epidural catheter was advanced to the 4th lumbar vertebra and MAC was determined after administration of saline and maropitant (1 mg kg(-1)) epidurally. All MAC determinations were done in duplicate. The MAC values were adjusted to sea level and compared using student's t-test. The baseline MAC for sevoflurane was 2.08 ± 0.25%. Intravenous maropitant decreased (p MAC by 16% (1.74 ± 0.17%). In contrast, epidural administration of either saline or maropitant did not change (p > 0.05) the MAC (2.17 ± 0.34% and 1.92 ± 0.12%, respectively). Maropitant decreased the MAC of sevoflurane when administered intravenously to dogs but not after epidural administration. © 2011 The Authors. Veterinary Anaesthesia and Analgesia. © 2011 Association of Veterinary Anaesthetists and the American College of Veterinary Anesthesiologists.

  17. Establishment of mouse Mac-2 binding protein enzyme-linked immunosorbent assay and its application for mouse chronic liver disease models.

    Science.gov (United States)

    Iwata, Ayumi; Kamada, Yoshihiro; Ebisutani, Yusuke; Yamamoto, Akiko; Ueda, Yui; Arai, Hitomi; Fujii, Hironobu; Takamatsu, Shinji; Maruyama, Nobuhiro; Maeda, Masahiro; Takehara, Tetsuo; Miyoshi, Eiji

    2017-08-01

    We identified Mac-2 (galectin-3) binding protein (Mac-2bp) as a novel diagnostic and liver fibrosis predicting biomarker for nonalcoholic steatohepatitis in humans. In mouse models, there are no serum biomarkers predicting liver disease severity. In this study, we developed a mouse Mac-2bp enzyme-linked immunosorbent assay (ELISA) system and determined its efficacy for predicting the severity of liver disease in mouse models, especially in non-alcoholic fatty liver disease (NAFLD) models. We established several rat monoclonal antibodies against mouse Mac-2bp, selected two clones for the ELISA, and checked the accuracy and reproducibility of the ELISA, especially for NAFLD models and liver fibrosis models. We also investigated the relationships between serum levels and hepatic gene expression of Mac-2bp in mouse models. Our ELISA system had high accuracy and reproducibility (R(2)  = 0.999). The intra-assay and inter-assay results for the coefficient of variation were 2.0-3.7% and 1.7-6.9%, respectively. The levels of bilirubin, hemoglobin, and chyle did not affect the Mac-2bp serum levels detected by our ELISA kit. In the mouse models, serum Mac-2bp levels increased with liver disease progression (F0/F1/F2/F3, 239.1 ± 36.7 / 259.1 ± 43.0 / 457.5 ± 162.0 / 643.7 ± 116.0 ng/mL; P Mac-2bp (R = 0.42, P Mac-2bp ELISA system effectively predicts severity of NAFLD and liver fibrosis in mouse models. © 2016 The Japan Society of Hepatology.

  18. Characterizing the Interaction Between Routing and MAC Protocols in Ad-Hoc Networks

    Energy Technology Data Exchange (ETDEWEB)

    Barrett, C. L. (Christopher L.); Drozda, M. (Martin); Marathe, A. (Achla); Marathe, M. V. (Madhav V.)

    2002-01-01

    We empirically study the effect of mobility on the performance of protocols designed for wireless ad-hoc networks. An important objective is to study the interaction of the Routing and MAC layer protocols under different mobility parameters. We use three basic mobility models: grid mobility model, random waypoint model, and exponential correlated random model. The performance of protocols is measured in terms of (i) latency, (ii) throughput, (iii) number of packets received, (iv) long term fairness and (v) number of control packets at the MAC and routing layer level. Three different commonly studied routing protocols are used: AODV, DSR and LAR1. Similarly three well known MAC protocols are used: MACA, 802.1 1 and CSMA. Our main contribution is simulation based experiments coupled with rigorous statistical analysis to characterize the interaction of MAC layer protocols with routing layer protocols in ad-hoc networks. From the results, we can conclude the following: e No single MAC or Routing protocol dominated the other protocols in their class. Probably more interestingly, no MAURouting protocol combination was better than other combinations over all scenarios and response variables. 0 In general, it is not meaningful to speak about a MAC or a routing protocol in isolation. Presence of interaction leads to trade-offs between the amount of control packets generated by each layer. The results raise the possibility of improving the performance of a particular MAC layer protocol by using a cleverly designed routing protocol or vice-versa. Thus in order to improve the performanceof a communication network, it is important to study the entire protocol stack as a single algorithmic construct; optimizing individual layers in the seven layer OS1 stack will not yield performance improvements beyond a point. A methodological contribution of this paper is the use of statistical methods such as analysis of variance (ANOVA), to characterize the interaction between the protocols

  19. The minimum alveolar concentration (MAC) of isoflurane in preterm neonates.

    Science.gov (United States)

    LeDez, K M; Lerman, J

    1987-09-01

    Studies in fetal lambs suggested that the minimum alveolar concentration (MAC) in preterm neonates may be less than that in full-term neonates and older infants. To determine the MAC of isoflurane in preterm neonates, 20 patients less than 32 weeks gestation at birth and 16 patients 32-37 weeks gestation at birth, all less than 1 month post-natal age, were studied. Following tracheal intubation, the neonates were anesthetized with a predetermined end-tidal concentration of isoflurane in oxygen and air. The move-no move responses to skin incision were recorded, and MAC was determined using the "up-and-down" technique. Heart rate and systolic arterial pressure were recorded awake, before skin incision, and after skin incision. MAC (mean +/- SD) of isoflurane in preterm neonates less than 32 weeks gestation was 1.28 +/- 0.17%, and MAC in neonates 32-37 weeks gestation was 1.41 +/- 0.18% (P less than 0.05). Although heart rate did not decrease significantly in either group during the study, systolic arterial pressure decreased between 20 and 30% below awake values both before and after skin incision in both age groups (P less than 0.01). We conclude that the MAC of isoflurane in preterm neonates less than 32 weeks gestation is significantly less than that in preterm neonates 32-37 weeks gestation, and that systolic arterial pressure decreases to a similar extent at approximately 1 MAC isoflurane in both age groups.

  20. Increased NMDA receptor inhibition at an increased Sevoflurane MAC

    Directory of Open Access Journals (Sweden)

    Brosnan Robert J

    2012-06-01

    Full Text Available Abstract Background Sevoflurane potently enhances glycine receptor currents and more modestly decreases NMDA receptor currents, each of which may contribute to immobility. This modest NMDA receptor antagonism by sevoflurane at a minimum alveolar concentration (MAC could be reciprocally related to large potentiation of other inhibitory ion channels. If so, then reduced glycine receptor potency should increase NMDA receptor antagonism by sevoflurane at MAC. Methods Indwelling lumbar subarachnoid catheters were surgically placed in 14 anesthetized rats. Rats were anesthetized with sevoflurane the next day, and a pre-infusion sevoflurane MAC was measured in duplicate using a tail clamp method. Artificial CSF (aCSF containing either 0 or 4 mg/mL strychnine was then infused intrathecally at 4 μL/min, and the post-infusion baseline sevoflurane MAC was measured. Finally, aCSF containing strychnine (either 0 or 4 mg/mL plus 0.4 mg/mL dizocilpine (MK-801 was administered intrathecally at 4 μL/min, and the post-dizocilpine sevoflurane MAC was measured. Results Pre-infusion sevoflurane MAC was 2.26%. Intrathecal aCSF alone did not affect MAC, but intrathecal strychnine significantly increased sevoflurane requirement. Addition of dizocilpine significantly decreased MAC in all rats, but this decrease was two times larger in rats without intrathecal strychnine compared to rats with intrathecal strychnine, a statistically significant (P  Conclusions Glycine receptor antagonism increases NMDA receptor antagonism by sevoflurane at MAC. The magnitude of anesthetic effects on a given ion channel may therefore depend on the magnitude of its effects on other receptors that modulate neuronal excitability.

  1. Increased NMDA receptor inhibition at an increased Sevoflurane MAC.

    Science.gov (United States)

    Brosnan, Robert J; Thiesen, Roberto

    2012-06-06

    Sevoflurane potently enhances glycine receptor currents and more modestly decreases NMDA receptor currents, each of which may contribute to immobility. This modest NMDA receptor antagonism by sevoflurane at a minimum alveolar concentration (MAC) could be reciprocally related to large potentiation of other inhibitory ion channels. If so, then reduced glycine receptor potency should increase NMDA receptor antagonism by sevoflurane at MAC. Indwelling lumbar subarachnoid catheters were surgically placed in 14 anesthetized rats. Rats were anesthetized with sevoflurane the next day, and a pre-infusion sevoflurane MAC was measured in duplicate using a tail clamp method. Artificial CSF (aCSF) containing either 0 or 4 mg/mL strychnine was then infused intrathecally at 4 μL/min, and the post-infusion baseline sevoflurane MAC was measured. Finally, aCSF containing strychnine (either 0 or 4 mg/mL) plus 0.4 mg/mL dizocilpine (MK-801) was administered intrathecally at 4 μL/min, and the post-dizocilpine sevoflurane MAC was measured. Pre-infusion sevoflurane MAC was 2.26%. Intrathecal aCSF alone did not affect MAC, but intrathecal strychnine significantly increased sevoflurane requirement. Addition of dizocilpine significantly decreased MAC in all rats, but this decrease was two times larger in rats without intrathecal strychnine compared to rats with intrathecal strychnine, a statistically significant (P MAC. The magnitude of anesthetic effects on a given ion channel may therefore depend on the magnitude of its effects on other receptors that modulate neuronal excitability.

  2. Neuroticism moderates the effect of maximum smoking level on lifetime panic disorder: a test using an epidemiologically defined national sample of smokers.

    Science.gov (United States)

    Zvolensky, Michael J; Sachs-Ericsson, Natalie; Feldner, Matthew T; Schmidt, Norman B; Bowman, Carrie J

    2006-03-30

    The present study evaluated a moderational model of neuroticism on the relation between smoking level and panic disorder using data from the National Comorbidity Survey. Participants (n=924) included current regular smokers, as defined by a report of smoking regularly during the past month. Findings indicated that a generalized tendency to experience negative affect (neuroticism) moderated the effects of maximum smoking frequency (i.e., number of cigarettes smoked per day during the period when smoking the most) on lifetime history of panic disorder even after controlling for drug dependence, alcohol dependence, major depression, dysthymia, and gender. These effects were specific to panic disorder, as no such moderational effects were apparent for other anxiety disorders. Results are discussed in relation to refining recent panic-smoking conceptual models and elucidating different pathways to panic-related problems.

  3. Multichannel MAC Layer In Mobile Ad—Hoc Network

    Science.gov (United States)

    Logesh, K.; Rao, Samba Siva

    2010-11-01

    This paper we presented the design objectives and technical challenges in Multichannel MAC protocols in Mobile Ad-hoc Network. In IEEE 802.11 a/b/g standards allow use of multiple channels, only a single channel is popularly used, due to the lack of efficient protocols that enable use of Multiple Channels. Even though complex environments in ad hoc networks require a combined control of physical (PHY) and medium access control (MAC) layers resources in order to optimize performance. And also we discuss the characteristics of cross-layer frame and give a multichannel MAC approach.

  4. Handling Deafness Problem of Scheduled Multi-Channel Polling MACs

    Science.gov (United States)

    Jiang, Fulong; Liu, Hao; Shi, Longxing

    Combining scheduled channel polling with channel diversity is a promising way for a MAC protocol to achieve high energy efficiency and performance under both light and heavy traffic conditions. However, the deafness problem may cancel out the benefit of channel diversity. In this paper, we first investigate the deafness problem of scheduled multi-channel polling MACs with experiments. Then we propose and evaluate two schemes to handle the deafness problem. Our experiment shows that deafness is a significant reason for performance degradation in scheduled multi-channel polling MACs. A proper scheme should be chosen depending on the traffic pattern and the design objective.

  5. Cooperative energy harvesting-adaptive MAC protocol for WBANs.

    Science.gov (United States)

    Esteves, Volker; Antonopoulos, Angelos; Kartsakli, Elli; Puig-Vidal, Manel; Miribel-Català, Pere; Verikoukis, Christos

    2015-05-28

    In this paper, we introduce a cooperative medium access control (MAC) protocol, named cooperative energy harvesting (CEH)-MAC, that adapts its operation to the energy harvesting (EH) conditions in wireless body area networks (WBANs). In particular, the proposed protocol exploits the EH information in order to set an idle time that allows the relay nodes to charge their batteries and complete the cooperation phase successfully. Extensive simulations have shown that CEH-MAC significantly improves the network performance in terms of throughput, delay and energy efficiency compared to the cooperative operation of the baseline IEEE 802.15.6 standard.

  6. A Hybrid MacCormack-type Scheme for Computational Aeroacoustics

    Science.gov (United States)

    Yazdani, Soroush

    A new type of MacCormack scheme, using a modified Low Dissipation and Dispersion Runge-Kutta time marching method, is presented. This scheme is using two stages in every step which implements biased spatial differencing stencils and for the remaining stages uses non-dissipative central differencing stencils. Because of using the MacCormack-type scheme in this method, the new scheme carries an inherent artificial dissipation which uses the ease of implementing boundary condition specifications of a two-stage MacCormack scheme.

  7. iMac G3 Blueberry 350MHz

    CERN Multimedia

    2000-01-01

    The iMac G3 is an all-in-one personal computer, encompassing both the monitor and the computer in one package. It allowed to revitalize the Apple brand that was in decline and close to financial ruin. Originally released in striking bondi blue and later a range of other translucent plastic envelopes in bright colors. The iMac comes with a keyboard and mouse matching the color of the case. The iMac G3 was sold from 1998 to 2003 and has been updated many times.

  8. Properties of dual codes defined by nondegenerate forms

    Directory of Open Access Journals (Sweden)

    Steve Szabo

    2017-01-01

    Full Text Available Dual codes are defined with respect to non-degenerate sesquilinear or bilinear forms over a finite Frobenius ring. These dual codes have the properties one expects from a dual code: they satisfy a double-dual property, they have cardinality complementary to that of the primal code, and they satisfy the MacWilliams identities for the Hamming weight.

  9. Throughput Analysis of Power Control B-MAC Protocol In WSN

    Directory of Open Access Journals (Sweden)

    Ramchand V

    2012-07-01

    Full Text Available This paper presents a new methodology for energy consumption of nodes and throughput analysis has been performed through simulation for B-MAC protocol in Wireless Sensor Networks. The design includes transmission power control and multi-hop transmission of frames through adjusted transmitted power level. Proposed model reduces collision with contention level notification. The proposed model has been simulated using MATLAB. The simulations reveal better results for throughput of the proposed model as compared to B-MAC protocol. In this model we have included a mechanism for node discovery to find the location of the node before transmission of data to it. This increases the throughput of the network since the position of a dislocated node has been found, that results into successful transmission of frames.However, the energy consumption of a node increases due to energy consumed in node discovery.

  10. PAD-MAC: primary user activity-aware distributed MAC for multi-channel cognitive radio networks.

    Science.gov (United States)

    Ali, Amjad; Piran, Md Jalil; Kim, Hansoo; Yun, Jihyeok; Suh, Doug Young

    2015-03-30

    Cognitive radio (CR) has emerged as a promising technology to solve problems related to spectrum scarcity and provides a ubiquitous wireless access environment. CR-enabled secondary users (SUs) exploit spectrum white spaces opportunistically and immediately vacate the acquired licensed channels as primary users (PUs) arrive. Accessing the licensed channels without the prior knowledge of PU traffic patterns causes severe throughput degradation due to excessive channel switching and PU-to-SU collisions. Therefore, it is significantly important to design a PU activity-aware medium access control (MAC) protocol for cognitive radio networks (CRNs). In this paper, we first propose a licensed channel usage pattern identification scheme, based on a two-state Markov model, and then estimate the future idle slots using previous observations of the channels. Furthermore, based on these past observations, we compute the rank of each available licensed channel that gives SU transmission success assessment during the estimated idle slot. Secondly, we propose a PU activity-aware distributed MAC (PAD-MAC) protocol for heterogeneous multi-channel CRNs that selects the best channel for each SU to enhance its throughput. PAD-MAC controls SU activities by allowing them to exploit the licensed channels only for the duration of estimated idle slots and enables predictive and fast channel switching. To evaluate the performance of the proposed PAD-MAC, we compare it with the distributed QoS-aware MAC (QC-MAC) and listen-before-talk MAC schemes. Extensive numerical results show the significant improvements of the PAD-MAC in terms of the SU throughput, SU channel switching rate and PU-to-SU collision rate.

  11. Infecting Windows, Linux & Mac in one go

    CERN Multimedia

    Computer Security Team

    2012-01-01

    Still love bashing on Windows as you believe it is an insecure operating system? Hold on a second! Just recently, a vulnerability has been published for Java 7.   It affects Windows/Linux PCs and Macs, Internet Explorer, Safari and Firefox. In fact, it affects all computers that have enabled the Java 7 plug-in in their browser (Java 6 and earlier is not affected). Once you visit a malicious website (and there are plenty already out in the wild), your computer is infected… That's "Game Over" for you.      And this is not the first time. For a while now, attackers have not been targeting the operating system itself, but rather aiming at vulnerabilities inherent in e.g. your Acrobat Reader, Adobe Flash or Java programmes. All these are standard plug-ins added into your favourite web browser which make your web-surfing comfortable (or impossible when you un-install them). A single compromised web-site, however, is sufficient to prob...

  12. Prior determination of baseline minimum alveolar concentration (MAC) of isoflurane does not influence the effect of ketamine on MAC in rabbits.

    Science.gov (United States)

    Gianotti, Giacomo; Valverde, Alexander; Sinclair, Melissa; Dyson, Doris H; Gibson, Thomas; Johnson, Ron

    2012-10-01

    The objective of this study was to compare the effect on the minimum alveolar concentration (MAC) of isoflurane when ketamine was administered either after or without prior determination of the baseline MAC of isoflurane in rabbits. Using a prospective randomized crossover study, 8 adult, female New Zealand rabbits were allocated to 2 treatment groups. Anesthesia was induced and maintained with isoflurane. Group 1 (same-day determination) had the MAC-sparing effect of ketamine [1 mg/kg bodyweight (BW) bolus followed by a constant rate infusion (CRI) of 40 μg/kg BW per min, given by intravenous (IV)], which was determined after the baseline MAC of isoflurane was determined beforehand. A third MAC determination was started 30 min after stopping the CRI. Group 2 (separate-day determination) had the MAC-sparing effect of ketamine determined without previous determination of the baseline MAC of isoflurane. A second MAC determination was started 30 min after stopping the CRI. In group 1, the MAC of isoflurane (2.15 ± 0.09%) was significantly decreased by ketamine (1.63 ± 0.07%). After stopping the CRI, the MAC was significantly less (2.04 ± 0.11%) than the baseline MAC of isoflurane and significantly greater than the MAC during the CRI. In group 2, ketamine decreased isoflurane MAC (1.53 ± 0.22%) and the MAC increased significantly (1.94 ± 0.25%) after stopping the CRI. Minimum alveolar concentration (MAC) values did not differ significantly between the groups either during ketamine administration or after stopping ketamine. Under the study conditions, prior determination of the baseline isoflurane MAC did not alter the effect of ketamine on MAC. Both methods of determining MAC seemed to be valid for research purposes.

  13. Histidine and Aspartic Acid Residues Important for Immunoglobulin G Endopeptidase Activity of the Group A Streptococcus Opsonophagocytosis-Inhibiting Mac Protein

    Science.gov (United States)

    Lei, Benfang; Liu, Mengyao; Meyers, Elishia G.; Manning, Heather M.; Nagiec, Michael J.; Musser, James M.

    2003-01-01

    The secreted Mac protein made by serotype M1 group A Streptococcus (GAS) (designated Mac5005) inhibits opsonophagocytosis and killing of GAS by human polymorphonuclear neutrophils. This protein also has cysteine endopeptidase activity against human immunoglobulin G (IgG). Site-directed mutagenesis was used to identify histidine and aspartic acid residues important for Mac IgG endopeptidase activity. Replacement of His262 with Ala abolished Mac5005 IgG endopeptidase activity. Asp284Ala and Asp286Ala mutant proteins had compromised enzymatic activity, whereas 21 other Asp-to-Ala mutant proteins cleaved human IgG at the apparent wild-type level. The results suggest that His262 is an active-site residue and that Asp284 and Asp286 are important for the enzymatic activity or structure of Mac protein. These Mac mutants provide new information about structure-activity relationships in this protein and will assist study of the mechanism of inhibition of opsonophagocytosis and killing of GAS by Mac. PMID:12704162

  14. Clinical evaluation of C-MAC videolaryngoscope with or without use of stylet for endotracheal intubation in patients with cervical spine immobilization.

    Science.gov (United States)

    Gupta, Nidhi; Rath, Girija Prasad; Prabhakar, Hemanshu

    2013-10-01

    This study was carried out to evaluate the relative efficacy of the C-MAC videolaryngoscope as compared to the conventional Macintosh laryngoscope using both styletted and non-styletted endotracheal tube (ETT) in patients undergoing elective cervical spine surgery with head and neck stabilized by manual in-line stabilization. We randomized 120 consenting adults into four groups (30 each) to undergo tracheal intubation using either the Macintosh laryngoscope or C-MAC videolaryngoscope with styletted and non-styletted ETT. There was no significant difference between the C-MAC videolaryngoscope and Macintosh laryngoscope in Intubation Difficulty Scale (IDS) score using either styletted [median (IQR) 2 (1, 3) vs. 3 (2, 4); p = 0.58] or non-styletted ETT [median (IQR) 4 (2, 6) vs. 3 (2, 8); p = 1.00]. Similarly, when using a similar ETT-stylet assembly, the duration of successful intubation attempt, first attempt success rate, complications, use of airway optimization maneuvers, and adjuncts to facilitate intubation were comparable. The Cormack-Lehane view of the glottis was better with the C-MAC videolaryngoscope (p MAC videolaryngoscope whereas no such effect was observed with the Macintosh laryngoscope. Use of the C-MAC videolaryngoscope and Macintosh laryngoscope resulted in similar levels of intubation difficulty during cervical immobilization when used with a similar ETT-stylet assembly. The inclusion of the stylet significantly reduced the intubation difficulty experienced with the C-MAC videolaryngoscope.

  15. Persimmon-derived tannin has bacteriostatic and anti-inflammatory activity in a murine model of Mycobacterium avium complex (MAC) disease.

    Science.gov (United States)

    Matsumura, Yoko; Kitabatake, Masahiro; Ouji-Sageshima, Noriko; Yasui, Satsuki; Mochida, Naoko; Nakano, Ryuichi; Kasahara, Kei; Tomoda, Koichi; Yano, Hisakazu; Kayano, Shin-Ichi; Ito, Toshihiro

    2017-01-01

    Nontuberculous mycobacteria (NTM), including Mycobacterium avium complex (MAC), cause opportunistic chronic pulmonary infections. Notably, MAC susceptibility is regulated by various factors, including the host immune system. Persimmon (Ebenaceae Diospyros kaki Thunb.) tannin is a condensed tannin composed of a polymer of catechin groups. It is well known that condensed tannins have high antioxidant activity and bacteriostatic properties. However, it is hypothesized that condensed tannins might need to be digested and/or fermented into smaller molecules in vivo prior to being absorbed into the body to perform beneficial functions. In this study, we evaluated the effects of soluble persimmon-derived tannins on opportunistic MAC disease. Soluble tannins were hydrolyzed and evaluated by the oxygen radical absorbance capacity (ORAC) method. The ORAC value of soluble tannin hydrolysate was approximately five times greater than that of soluble tannin powder. In addition, soluble tannin hydrolysate exhibited high bacteriostatic activity against MAC in vitro. Furthermore, in an in vivo study, MAC infected mice fed a soluble tannin-containing diet showed significantly higher anti-bacterial activity against MAC and less pulmonary granuloma formation compared with those fed a control diet. Tumor necrosis factor α and inducible nitric oxide synthase levels were significantly lower in lungs of the soluble tannin diet group compared with the control diet group. Moreover, proinflammatory cytokines induced by MAC stimulation of bone marrow-derived macrophages were significantly decreased by addition of soluble tannin hydrolysate. These data suggest that soluble tannin from persimmons might attenuate the pathogenesis of pulmonary NTM infection.

  16. Competition at the Wireless Sensor Network MAC Layer: Low Power Probing interfering with X-MAC

    Science.gov (United States)

    Zacharias, Sven; Newe, Thomas

    2011-08-01

    Wireless Sensor Networks (WSNs) combine sensors with computer networks and enable very dense, in-situ and live measurements of data over a large area. Since this emerging technology has the potential to be embedded almost everywhere for numberless applications, interference between different networks can become a serious issue. For most WSNs, it is assumed today that the network medium access is non-competitive. On the basis of X-MAC interfered by Low Power Probing, this paper shows the danger and the effects of different sensor networks communicating on a single wireless channel of the 2.4 GHz band, which is used by the IEEE 802.15.4 standard.

  17. After MacIntyre : Kaasaegsest vooruseetikast / Meego Remmel

    Index Scriptorium Estoniae

    Remmel, Meego

    2006-01-01

    Alasdair MacIntyre panus 20. sajandi eetikasse. Tema käsitlus vooruseetikast ja vooruseetilisest perspektiivist, mida on võimalik näha komplekselt, vaadeldes voorust, praktikat, narratiivi ja traditsiooni mõisteid

  18. After MacIntyre : Kaasaegsest vooruseetikast / Meego Remmel

    Index Scriptorium Estoniae

    Remmel, Meego

    2006-01-01

    Alasdair MacIntyre panus 20. sajandi eetikasse. Tema käsitlus vooruseetikast ja vooruseetilisest perspektiivist, mida on võimalik näha komplekselt, vaadeldes voorust, praktikat, narratiivi ja traditsiooni mõisteid

  19. Design and Implementation of an Efficient 64 bit MAC

    Directory of Open Access Journals (Sweden)

    Mohammad Shabber Hasan Khan

    2015-08-01

    Full Text Available The design of optimized 64 bit multiplier and accumulator (MAC unit is implemented in this paper. MAC unit plays major role in many of the digital signal processing (DSP applications. The MAC unit is designed with the combinations of multipliers and adders. In the proposed method MAC unit is implemented using Vedic multiplier and the adder is done with ripple carry adder .The components are reduced by implementing Vedic multiplier using the techniques of Vedic mathematics that have been modified to improve performance. a high speed processor depends significantly on the multiplier as it is one of the key hardware blocks in most digital signal processing systems as well as in general processors. The area is optimized effectively using Vedic multiplier .The total design implemented using Xilinx.

  20. Beamforming in Ad Hoc Networks: MAC Design and Performance Modeling

    National Research Council Canada - National Science Library

    Fakih, Khalil; Diouris, Jean-Francois; Andrieux, Guillaume

    2009-01-01

    .... Our proposition performs jointly channel estimation and radio resource sharing. We validate the fruitfulness of the proposed MAC and we evaluate the effects of the channel estimation on the network performance...

  1. Aeronautical Mobile Airport Communications System (AeroMACS)

    Science.gov (United States)

    Budinger, James M.; Hall, Edward

    2011-01-01

    To help increase the capacity and efficiency of the nation s airports, a secure wideband wireless communications system is proposed for use on the airport surface. This paper provides an overview of the research and development process for the Aeronautical Mobile Airport Communications System (AeroMACS). AeroMACS is based on a specific commercial profile of the Institute of Electrical and Electronics Engineers (IEEE) 802.16 standard known as Wireless Worldwide Interoperability for Microwave Access or WiMAX (WiMax Forum). The paper includes background on the need for global interoperability in air/ground data communications, describes potential AeroMACS applications, addresses allocated frequency spectrum constraints, summarizes the international standardization process, and provides findings and recommendations from the world s first AeroMACS prototype implemented in Cleveland, Ohio, USA.

  2. Rating of new outlet structures for MacFarlane Reservoir

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — Memorandum explaining the new work on the outlet structure at MacFarlane Reservoir. Flow measurements were taken at different staff gage elevations and this data is...

  3. Big Mac arvestab raha ostujõudu / Harli Uljas

    Index Scriptorium Estoniae

    Uljas, Harli

    2005-01-01

    The Economist võrdleb maailma valuutade suhestamiseks Big Mac'i burgeri hindu 120 riigis, kuna see meetod võimaldab saada ülevaate riikide elanikkonna tegelikust ostujõust. Tabel: Hamburgeri standard

  4. Big Mac arvestab raha ostujõudu / Harli Uljas

    Index Scriptorium Estoniae

    Uljas, Harli

    2005-01-01

    The Economist võrdleb maailma valuutade suhestamiseks Big Mac'i burgeri hindu 120 riigis, kuna see meetod võimaldab saada ülevaate riikide elanikkonna tegelikust ostujõust. Tabel: Hamburgeri standard

  5. MAC layer security issues in wireless mesh networks

    Science.gov (United States)

    Reddy, K. Ganesh; Thilagam, P. Santhi

    2016-03-01

    Wireless Mesh Networks (WMNs) have emerged as a promising technology for a broad range of applications due to their self-organizing, self-configuring and self-healing capability, in addition to their low cost and easy maintenance. Securing WMNs is more challenging and complex issue due to their inherent characteristics such as shared wireless medium, multi-hop and inter-network communication, highly dynamic network topology and decentralized architecture. These vulnerable features expose the WMNs to several types of attacks in MAC layer. The existing MAC layer standards and implementations are inadequate to secure these features and fail to provide comprehensive security solutions to protect both backbone and client mesh. Hence, there is a need for developing efficient, scalable and integrated security solutions for WMNs. In this paper, we classify the MAC layer attacks and analyze the existing countermeasures. Based on attacks classification and countermeasures analysis, we derive the research directions to enhance the MAC layer security for WMNs.

  6. Mac OS X : Tiger edition the missing manual

    CERN Document Server

    Pogue, David

    2005-01-01

    You can set your watch to it: As soon as Apple comes out with another version of Mac OS X, David Pogue hits the streets with another meticulous Missing Manual to cover it with a wealth of detail. The new Mac OS X 10.4, better known as Tiger, is faster than its predecessors, but nothing's too fast for Pogue and Mac OS X: The Missing Manual. There are many reasons why this is the most popular computer book of all time. With its hallmark objectivity, the Tiger Edition thoroughly explores the latest features to grace the Mac OS. Which ones work well and which do not? What should you look for? Th

  7. Defining biobank.

    Science.gov (United States)

    Hewitt, Robert; Watson, Peter

    2013-10-01

    The term "biobank" first appeared in the scientific literature in 1996 and for the next five years was used mainly to describe human population-based biobanks. In recent years, the term has been used in a more general sense and there are currently many different definitions to be found in reports, guidelines and regulatory documents. Some definitions are general, including all types of biological sample collection facilities. Others are specific and limited to collections of human samples, sometimes just to population-based collections. In order to help resolve the confusion on this matter, we conducted a survey of the opinions of people involved in managing sample collections of all types. This survey was conducted using an online questionnaire that attracted 303 responses. The results show that there is consensus that the term biobank may be applied to biological collections of human, animal, plant or microbial samples; and that the term biobank should only be applied to sample collections with associated sample data, and to collections that are managed according to professional standards. There was no consensus on whether a collection's purpose, size or level of access should determine whether it is called a biobank. Putting these findings into perspective, we argue that a general, broad definition of biobank is here to stay, and that attention should now focus on the need for a universally-accepted, systematic classification of the different biobank types.

  8. Evaluation of Fucosylated Haptoglobin and Mac-2 Binding Protein as Serum Biomarkers to Estimate Liver Fibrosis in Patients with Chronic Hepatitis C.

    Science.gov (United States)

    Tawara, Seiichi; Tatsumi, Tomohide; Iio, Sadaharu; Kobayashi, Ichizou; Shigekawa, Minoru; Hikita, Hayato; Sakamori, Ryotaro; Hiramatsu, Naoki; Miyoshi, Eiji; Takehara, Tetsuo

    2016-01-01

    Fucosylated haptoglobin (Fuc-Hpt) and Mac-2 binding protein (Mac-2 bp) are identified as cancer biomarkers, based on the results from a glyco-proteomic analysis. Recently, we reported that these glyco-biomarkers were associated with liver fibrosis and/or ballooning hepatocytes in patients with nonalcoholic fatty liver disease (NAFLD). We evaluated the ability of these glycoproteins to estimate liver fibrosis in 317 patients with chronic hepatitis C. We measured the serum Fuc-Hpt and Mac-2 bp levels using a lectin-antibody ELISA and ELISA, respectively. The serum levels of both Fuc-Hpt and Mac-2 bp increased with the progression of liver fibrosis. The multivariate analysis revealed that Mac-2 bp was an independent factor associated with moderate liver fibrosis (F ≥ 2). In contrast, Fuc-Hpt was an independent factor associated with advanced liver fibrosis (F ≥ 3). In terms of evaluating liver fibrosis, the serum levels of these glycomarkers were correlated with well-known liver fibrosis indexes, such as the aspartate aminotransferase to platelet ratio index (APRI) and Fibrosis-4 (FIB4) index. An assay that combined the APRI or FIB4 index and the Fuc-Hpt or Mac-2 bp levels increased the AUC value for diagnosing hepatic fibrosis. Interestingly, the cumulative incidence of hepatocellular carcinoma (HCC) was significantly higher in the patients with elevated serum levels of Fuc-Hpt and Mac-2 bp. In conclusion, both Fuc-Hpt and Mac-2 bp could be useful glyco-biomarkers of liver fibrosis and predictors of HCC in patients with chronic hepatitis C.

  9. A tribute to Lloyd D. MacLean.

    Science.gov (United States)

    Keith, Roger G

    2015-08-01

    Dr. Lloyd D. MacLean, long-time co-editor of the Canadian Journal of Surgery passed away earlier this year at the age of 90. In order to appreciate the contributions of Dr. MacLean to the journal, this commentary recognizes him as a humble surgeon–scientist who was one of — if not the — most outstanding Canadian ambassadors to academic surgery in North America.

  10. Conformal holonomy in MacDowell-Mansouri gravity

    Energy Technology Data Exchange (ETDEWEB)

    Reid, James A., E-mail: j.a.reid@abdn.ac.uk [SUPA Department of Physics, University of Aberdeen, Aberdeen, AB24 3UE (United Kingdom); Wang, Charles H.-T., E-mail: c.wang@abdn.ac.uk [SUPA Department of Physics, University of Aberdeen, Aberdeen, AB24 3UE (United Kingdom); STFC Rutherford Appleton Laboratory, Chilton, Didcot, Oxon, OX11 0QX (United Kingdom)

    2014-03-15

    The MacDowell-Mansouri formulation of general relativity is based on a gauge theory whose gauge algebra depends on the sign of the cosmological constant. In this article, we show that the gauge algebra is uniquely determined by the conformal structure of spacetime itself. Specifically, we show that in vacuum: the spacetime conformal holonomy algebra coincides with the MacDowell-Mansouri gauge algebra for both signs of the cosmological constant, in both Lorentzian and Euclidean metric signatures.

  11. Some Problems of Alasdair MacIntyre’s "Emotivism Thesis"

    OpenAIRE

    2016-01-01

    In this article Alasdair MacIntyre’s thesis concerning emotivist use of moral utterances in contemporary liberal societies is analysed. One tries to show that it needs further clarification since at least three elements of MacIntyre’s argument seem to pose certain problems; these are: ‘discussion halt’ as the source of emotivism, comprehensive doctrines as premises of respective arguments in liberal debates and the problem of incommensurability. These three problematic eleme...

  12. MacCormack's technique-based pressure reconstruction approach for PIV data in compressible flows with shocks

    Science.gov (United States)

    Liu, Shun; Xu, Jinglei; Yu, Kaikai

    2017-06-01

    This paper proposes an improved approach for extraction of pressure fields from velocity data, such as obtained by particle image velocimetry (PIV), especially for steady compressible flows with strong shocks. The principle of this approach is derived from Navier-Stokes equations, assuming adiabatic condition and neglecting viscosity of flow field boundaries measured by PIV. The computing method is based on MacCormack's technique in computational fluid dynamics. Thus, this approach is called the MacCormack method. Moreover, the MacCormack method is compared with several approaches proposed in previous literature, including the isentropic method, the spatial integration and the Poisson method. The effects of velocity error level and PIV spatial resolution on these approaches are also quantified by using artificial velocity data containing shock waves. The results demonstrate that the MacCormack method has higher reconstruction accuracy than other approaches, and its advantages become more remarkable with shock strengthening. Furthermore, the performance of the MacCormack method is also validated by using synthetic PIV images with an oblique shock wave, confirming the feasibility and advantage of this approach in real PIV experiments. This work is highly significant for the studies on aerospace engineering, especially the outer flow fields of supersonic aircraft and the internal flow fields of ramjets.

  13. 42 CFR 423.2102 - Request for MAC review when ALJ issues decision or dismissal.

    Science.gov (United States)

    2010-10-01

    ... 42 Public Health 3 2010-10-01 2010-10-01 false Request for MAC review when ALJ issues decision or... Reopening, ALJ Hearings, MAC review, and Judicial Review § 423.2102 Request for MAC review when ALJ issues decision or dismissal. (a)(1) An enrollee to the ALJ hearing may request a MAC review if the enrollee files...

  14. 42 CFR 423.2062 - Applicability of policies not binding on the ALJ and MAC.

    Science.gov (United States)

    2010-10-01

    ... and MAC. 423.2062 Section 423.2062 Public Health CENTERS FOR MEDICARE & MEDICAID SERVICES, DEPARTMENT... BENEFIT Reopening, ALJ Hearings, MAC review, and Judicial Review § 423.2062 Applicability of policies not binding on the ALJ and MAC. (a) ALJs and the MAC are not bound by CMS program guidance, such as program...

  15. 42 CFR 423.2110 - MAC reviews on its own motion.

    Science.gov (United States)

    2010-10-01

    ... 42 Public Health 3 2010-10-01 2010-10-01 false MAC reviews on its own motion. 423.2110 Section 423... (CONTINUED) MEDICARE PROGRAM VOLUNTARY MEDICARE PRESCRIPTION DRUG BENEFIT Reopening, ALJ Hearings, MAC review, and Judicial Review § 423.2110 MAC reviews on its own motion. (a) General rule. The MAC may decide on...

  16. 42 CFR 423.2050 - Removal of a hearing request from an ALJ to the MAC.

    Science.gov (United States)

    2010-10-01

    ... 42 Public Health 3 2010-10-01 2010-10-01 false Removal of a hearing request from an ALJ to the MAC..., ALJ Hearings, MAC review, and Judicial Review § 423.2050 Removal of a hearing request from an ALJ to the MAC. If a request for hearing is pending before an ALJ, the MAC may assume responsibility for...

  17. 42 CFR 423.2108 - MAC Actions when request for review is filed.

    Science.gov (United States)

    2010-10-01

    ... 42 Public Health 3 2010-10-01 2010-10-01 false MAC Actions when request for review is filed. 423... Hearings, MAC review, and Judicial Review § 423.2108 MAC Actions when request for review is filed. (a) General. Except as specified in paragraph (c) of this section, when an enrollee requests that the MAC...

  18. Connectivity-Based Reliable Multicast MAC Protocol for IEEE 802.11 Wireless LANs

    Directory of Open Access Journals (Sweden)

    Woo-Yong Choi

    2009-01-01

    Full Text Available We propose the efficient reliable multicast MAC protocol based on the connectivity information among the recipients. Enhancing the BMMM (Batch Mode Multicast MAC protocol, the reliable multicast MAC protocol significantly reduces the RAK (Request for ACK frame transmissions in a reasonable computational time and enhances the MAC performance. By the analytical performance analysis, the throughputs of the BMMM protocol and our proposed MAC protocol are derived. Numerical examples show that our proposed MAC protocol increases the reliable multicast MAC performance for IEEE 802.11 wireless LANs.

  19. Poikilocapnic hypoxic ventilatory response in humans during 0.85 MAC isoflurane anesthesia.

    Science.gov (United States)

    Sjögren, D; Sollevi, A; Ebberyd, A; Lindahl, S G

    1994-02-01

    Ventilatory responses to hypoxia (HVR) were investigated using poikilocapnic conditions (i.e. end-tidal CO2's allowed to seek it's own level) in 15 cardio-pulmonary healthy patients who were first studied awake and then at 0.85 MAC isoflurane. The influence of hypercapnia (HyperCapnic Ventilatory Response, HCVR) was also elucidated. Pneumotachography, capnography and airway occlusion pressures at 0.1 s (P degree 0.1) were used before and during both mild hypoxia (end-tidal O2 tension 8.7 kPa) and hypercapnia achieved by an inspired CO2 concentration of 5%. HCVR was attenuated by 60% during anesthesia (P awake state, five of the 15 patients decreased HVR during hypoxia as compared with during normoxia. This resulted in a VE that on average increased by 0.6 l.min-1 (P MAC isoflurane.

  20. Searching for lower female genital tract soluble and cellular biomarkers: defining levels and predictors in a cohort of healthy Caucasian women.

    Directory of Open Access Journals (Sweden)

    Jordan K Kyongo

    Full Text Available BACKGROUND: High concentrations of pro-inflammatory cytokines have been previously observed in the genital fluids of women enrolled in microbicide trials and may explain observed increased HIV transmission in some of these trials. Although the longitudinal nature of these studies allows within-subject comparisons of post-product levels to baseline levels, the fact that the physiologic variations of these cytokines and other markers of immune activation are not fully defined in different populations, makes it difficult to assess changes that can be directly attributed to microbicide use as opposed to other biological and behavioural factors. METHODS: Cervicovaginal lavage samples were collected from 30 healthy Caucasian and assayed for concentrations of ten cytokines/chemokines, total protein content and two antimicrobial proteins using a multiplex immunoassay and ELISA. Cellular markers were characterized by flow cytometry on mononuclear cells collected from the endocervix using flocked swabs. Bacterial quantification was performed using quantitative PCR. RESULTS: Ectopy, menstrual cycle phase, prostate-specific antigen and presence of leucocytes in endocervical cells' supernatant were associated with the concentrations of cyto-/chemokines in cervicovaginal secretions. Approximately 3% of endocervical cells collected were monocytes of which a median of 52% (SD  = 17 expressed both CD4 and CCR5 markers. Approximately 1% of the total cells were T-cells with a median of 61% (SD  = 10 CD4 and CCR5 expression. Around 5% of the monocytes and 16% of the T-cells expressed the immune activation marker HLA-DR. Higher percentages of T-cells were associated with greater quantities of IL-1RA, GM-CSF and elafin. CONCLUSION: We demonstrate the presence of selected soluble and cellular immune activation markers and identify their predictors in the female genital tract of healthy women. Future clinical trials should consider ectopy, sexual activity

  1. Anaesthesia with sevoflurane in pigeons: minimal anaesthetic concentration (MAC) determination and investigation of cardiorespiratory variables at 1 MAC.

    Science.gov (United States)

    Botman, J; Gabriel, F; Dugdale, A H A; Vandeweerd, J-M

    2016-05-28

    The objective of the study was to determine the minimal anaesthetic concentration (MAC) of sevoflurane (SEVO) in pigeons and investigate the effects of 1 MAC SEVO anaesthesia on cardiovascular and respiratory variables compared with the awake state. This is a prospective, experimental study. Animals were seven healthy adult pigeons. After acclimatisation to handling, heart rate (HR), heart rhythm, respiratory rate (fR), end-expired carbon dioxide tension (PE'CO2), inspired CO2 tension, indirect systolic arterial blood pressure (SAP) and cloacal temperature were measured to determine baseline, 'awake' values. Pigeons were then anaesthetised with SEVO and MAC was determined by the 'bracketing' method. The same variables were monitored during a 40 minute period at 1.0 MAC SEVO for each bird. Mean MAC was 3.0±0.6 per cent for SEVO. During maintenance of anaesthesia at 1.0 MAC, SAP decreased significantly (Pawake PE'CO2 values were unexpectedly low. Sinus arrhythmias were detected in two birds under SEVO anaesthesia. The times to tracheal intubation and to recovery were 2.5±0.7 and 6.4±1.7 minutes, respectively. Recovery was rapid and uneventful in all birds. In conclusion, SEVO is suitable for anaesthesia in pigeons. British Veterinary Association.

  2. Learning Unix for Mac OS X Tiger Unlock the Power of Unix

    CERN Document Server

    Taylor, Dave

    2005-01-01

    Thoroughly revised and updated for Mac OS X Tiger, this new edition introduces Mac users to the Terminal application and shows you how to navigate the command interface, explore hundreds of Unix applications that come with the Mac, and, most importantly, how to take advantage of both the Mac and Unix interfaces. If you want to master the command-line, this gentle guide to using Unix on Mac OS X Tiger is well worth its cover price

  3. C-Band Airport Surface Communications System Standards Development. Phase II Final Report. Volume 1: Concepts of Use, Initial System Requirements, Architecture, and AeroMACS Design Considerations

    Science.gov (United States)

    Hall, Edward; Isaacs, James; Henriksen, Steve; Zelkin, Natalie

    2011-01-01

    This report is provided as part of ITT s NASA Glenn Research Center Aerospace Communication Systems Technical Support (ACSTS) contract NNC05CA85C, Task 7: New ATM Requirements-Future Communications, C-Band and L-Band Communications Standard Development and was based on direction provided by FAA project-level agreements for New ATM Requirements-Future Communications. Task 7 included two subtasks. Subtask 7-1 addressed C-band (5091- to 5150-MHz) airport surface data communications standards development, systems engineering, test bed and prototype development, and tests and demonstrations to establish operational capability for the Aeronautical Mobile Airport Communications System (AeroMACS). Subtask 7-2 focused on systems engineering and development support of the L-band digital aeronautical communications system (L-DACS). Subtask 7-1 consisted of two phases. Phase I included development of AeroMACS concepts of use, requirements, architecture, and initial high-level safety risk assessment. Phase II builds on Phase I results and is presented in two volumes. Volume I (this document) is devoted to concepts of use, system requirements, and architecture, including AeroMACS design considerations. Volume II describes an AeroMACS prototype evaluation and presents final AeroMACS recommendations. This report also describes airport categorization and channelization methodologies. The purposes of the airport categorization task were (1) to facilitate initial AeroMACS architecture designs and enable budgetary projections by creating a set of airport categories based on common airport characteristics and design objectives, and (2) to offer high-level guidance to potential AeroMACS technology and policy development sponsors and service providers. A channelization plan methodology was developed because a common global methodology is needed to assure seamless interoperability among diverse AeroMACS services potentially supplied by multiple service providers.

  4. C-Band Airport Surface Communications System Standards Development. Phase II Final Report. Volume 2: Test Bed Performance Evaluation and Final AeroMACS Recommendations

    Science.gov (United States)

    Hall, Edward; Magner, James

    2011-01-01

    This report is provided as part of ITT s NASA Glenn Research Center Aerospace Communication Systems Technical Support (ACSTS) contract NNC05CA85C, Task 7: New ATM Requirements-Future Communications, C-Band and L-Band Communications Standard Development and was based on direction provided by FAA project-level agreements for New ATM Requirements-Future Communications. Task 7 included two subtasks. Subtask 7-1 addressed C-band (5091- to 5150-MHz) airport surface data communications standards development, systems engineering, test bed and prototype development, and tests and demonstrations to establish operational capability for the Aeronautical Mobile Airport Communications System (AeroMACS). Subtask 7-2 focused on systems engineering and development support of the L-band digital aeronautical communications system (L-DACS). Subtask 7-1 consisted of two phases. Phase I included development of AeroMACS concepts of use, requirements, architecture, and initial high-level safety risk assessment. Phase II builds on Phase I results and is presented in two volumes. Volume I is devoted to concepts of use, system requirements, and architecture, including AeroMACS design considerations. Volume II (this document) describes an AeroMACS prototype evaluation and presents final AeroMACS recommendations. This report also describes airport categorization and channelization methodologies. The purposes of the airport categorization task were (1) to facilitate initial AeroMACS architecture designs and enable budgetary projections by creating a set of airport categories based on common airport characteristics and design objectives, and (2) to offer high-level guidance to potential AeroMACS technology and policy development sponsors and service providers. A channelization plan methodology was developed because a common global methodology is needed to assure seamless interoperability among diverse AeroMACS services potentially supplied by multiple service providers.

  5. Pliable Cognitive MAC for Heterogeneous Adaptive Cognitive Radio Sensor Networks.

    Directory of Open Access Journals (Sweden)

    Mohammed Al-Medhwahi

    Full Text Available The rapid expansion of wireless monitoring and surveillance applications in several domains reinforces the trend of exploiting emerging technologies such as the cognitive radio. However, these technologies have to adjust their working concepts to consider the common characteristics of conventional wireless sensor networks (WSNs. The cognitive radio sensor network (CRSN, still an immature technology, has to deal with new networks that might have different types of data, traffic patterns, or quality of service (QoS requirements. In this paper, we design and model a new cognitive radio-based medium access control (MAC algorithm dealing with the heterogeneous nature of the developed networks in terms of either the traffic pattern or the required QoS for the node applications. The proposed algorithm decreases the consumed power on several fronts, provides satisfactory levels of latency and spectrum utilization with efficient scheduling, and manages the radio resources for various traffic conditions. An intensive performance evaluation is conducted to study the impact of key parameters such as the channel idle time length, node density, and the number of available channels. The performance evaluation of the proposed algorithm shows a better performance than the comparable protocols. Moreover, the results manifest that the proposed algorithm is suitable for real time monitoring applications.

  6. Pliable Cognitive MAC for Heterogeneous Adaptive Cognitive Radio Sensor Networks.

    Science.gov (United States)

    Al-Medhwahi, Mohammed; Hashim, Fazirulhisyam; Ali, Borhanuddin Mohd; Sali, Aduwati

    2016-01-01

    The rapid expansion of wireless monitoring and surveillance applications in several domains reinforces the trend of exploiting emerging technologies such as the cognitive radio. However, these technologies have to adjust their working concepts to consider the common characteristics of conventional wireless sensor networks (WSNs). The cognitive radio sensor network (CRSN), still an immature technology, has to deal with new networks that might have different types of data, traffic patterns, or quality of service (QoS) requirements. In this paper, we design and model a new cognitive radio-based medium access control (MAC) algorithm dealing with the heterogeneous nature of the developed networks in terms of either the traffic pattern or the required QoS for the node applications. The proposed algorithm decreases the consumed power on several fronts, provides satisfactory levels of latency and spectrum utilization with efficient scheduling, and manages the radio resources for various traffic conditions. An intensive performance evaluation is conducted to study the impact of key parameters such as the channel idle time length, node density, and the number of available channels. The performance evaluation of the proposed algorithm shows a better performance than the comparable protocols. Moreover, the results manifest that the proposed algorithm is suitable for real time monitoring applications.

  7. C-MAC compared with direct laryngoscopy for intubation in patients with cervical spine immobilization: A manikin trial.

    Science.gov (United States)

    Smereka, Jacek; Ladny, Jerzy R; Naylor, Amanda; Ruetzler, Kurt; Szarpak, Lukasz

    2017-08-01

    The aim of this study was to compare C-MAC videolaryngoscopy with direct laryngoscopy for intubation in simulated cervical spine immobilization conditions. The study was designed as a prospective randomized crossover manikin trial. 70 paramedics with MAC and C-MAC on the first attempt (95.7% MAC vs. 100% C-MAC), with similar intubation times (16.5s MAC vs. 18s C-MAC). Scenario B: The results with C-MAC were significantly better than those with MAC (pMAC vs. 19 s C-MAC), success of the first intubation attempt (88.6% MAC vs. 100% C-MAC), Cormack-Lehane grade, POGO score, severity of dental compression, device difficulty score, and preferred airway device. Scenario C: The results with C-MAC were significantly better than those with MAC (pMAC vs. 100% C-MAC), overall success rate, intubation time (27 s MAC vs. 20.5 s C-MAC), Cormack-Lehane grade, POGO score, dental compression, device difficulty score and the preferred airway device. The C-MAC videolaryngoscope is an excellent alternative to the MAC laryngoscope for intubating manikins with cervical spine immobilization. Copyright © 2017 Elsevier Inc. All rights reserved.

  8. Victor Bérard et la Macédoine

    Directory of Open Access Journals (Sweden)

    Ivan Savev

    2011-01-01

    Full Text Available Un helléniste convaincu, Victor Bérard, en vient, au début du XXe siècle à soutenir l’existence de « Macédoniens » et le slogan « la Macédoine aux Macédoniens”.Le Congrès de Berlin en 1878 avait laissé la Macédoine aux mains des Ottomans. La Grèce, la Serbie et la Bulgarie, parvenues à ses limites et prévoyant le retrait futur des Ottomans peaufinent les arguments linguistiques et historiques qui justifieront leurs revendications territoriales. Victor Bérard, un helléniste respecté et bon connaisseur de la région sud balkanique, effectue des enquêtes en Macédoine en 1896 et 1903 qu’il publie à Paris.Cette étude montre comment, dans le contexte de la propagande nationaliste des prétendants à la possession de la Macédoine, Victor Bérard en vient progressivement à affirmer qu’il existe une population autochtone, les Macédoniens. Il soutient leur programme pour la constitution d’une fédération ou confédération avec le slogan « la Macédoine aux Macédoniens » ce qui fait toute l’actualité de ses ouvrages.In 1878, the Congress of Berlin had left Macedonia in the hands of the Ottomans. Greece, Serbia and Bulgaria had reached its limits. Anticipating the Ottoman retreat, they polish language and historical arguments that will justify their territorial claims. Victor Bérard, a respected Hellenist and a good expert of the southern Balkans, is doing researches in Macedonia in 1896 and 1903. These will be later published in Paris.This study shows how, in the context of the nationalist propaganda build-up made by the candidates for the possession of Macedonia, Victor Bérard comes progressively to assert the existence of a native population: the Macedonians. He supports their program for the forming of a federation or confederation which slogan would be “Macedonia to Macedonians”. This makes his works very topical.

  9. The many faces of Mac-1 in autoimmune disease.

    Science.gov (United States)

    Rosetti, Florencia; Mayadas, Tanya N

    2016-01-01

    Mac-1 (CD11b/CD18) is a β2 integrin classically regarded as a pro-inflammatory molecule because of its ability to promote phagocyte cytotoxic functions and enhance the function of several effector molecules such as FcγR, uPAR, and CD14. Nevertheless, recent reports have revealed that Mac-1 also plays significant immunoregulatory roles, and genetic variants in ITGAM, the gene that encodes CD11b, confer risk for the autoimmune disease systemic lupus erythematosus (SLE). This has renewed interest in the physiological roles of this integrin and raised new questions on how its seemingly opposing biological functions may be regulated. Here, we provide an overview of the CD18 integrins and how their activation may be regulated as this may shed light on how the opposing roles of Mac-1 may be elicited. We then discuss studies that exemplify Mac-1's pro-inflammatory versus regulatory roles particularly in the context of IgG immune complex-mediated inflammation. This includes a detailed examination of molecular mechanisms that could explain the risk-conferring effect of rs1143679, a single nucleotide non-synonymous Mac-1 polymorphism associated with SLE.

  10. Magnetically assisted chemical separation (MACS) process: Preparation and optimization of particles for removal of transuranic elements

    Energy Technology Data Exchange (ETDEWEB)

    Nunez, L.; Kaminski, M.; Bradley, C.; Buchholz, B.A.; Aase, S.B.; Tuazon, H.E.; Vandegrift, G.F. [Argonne National Lab., IL (United States); Landsberger, S. [Univ. of Illinois, Urbana, IL (United States)

    1995-05-01

    The Magnetically Assisted Chemical Separation (MACS) process combines the selectivity afforded by solvent extractants with magnetic separation by using specially coated magnetic particles to provide a more efficient chemical separation of transuranic (TRU) elements, other radionuclides, and heavy metals from waste streams. Development of the MACS process uses chemical and physical techniques to elucidate the properties of particle coatings and the extent of radiolytic and chemical damage to the particles, and to optimize the stages of loading, extraction, and particle regeneration. This report describes the development of a separation process for TRU elements from various high-level waste streams. Polymer-coated ferromagnetic particles with an adsorbed layer of octyl(phenyl)-N,N-diisobutylcarbamoylmethylphosphine oxide (CMPO) diluted with tributyl phosphate (TBP) were evaluated for use in the separation and recovery of americium and plutonium from nuclear waste solutions. Due to their chemical nature, these extractants selectively complex americium and plutonium contaminants onto the particles, which can then be recovered from the solution by using a magnet. The partition coefficients were larger than those expected based on liquid[liquid extractions, and the extraction proceeded with rapid kinetics. Extractants were stripped from the particles with alcohols and 400-fold volume reductions were achieved. Particles were more sensitive to acid hydrolysis than to radiolysis. Overall, the optimization of a suitable NMCS particle for TRU separation was achieved under simulant conditions, and a MACS unit is currently being designed for an in-lab demonstration.

  11. Extended-reach slant drilling application : MacKay River SAGD project

    Energy Technology Data Exchange (ETDEWEB)

    Teotico, D.; Van Thiel, A. [Petro-Canada, Calgary, AB (Canada)

    2008-07-01

    The thermal in-situ method is commonly used and involves the injection of steam to reduce the viscosity of oil. This presentation discussed an extended-reach slant drilling application known as the MacKay River steam-assisted gravity drainage (SAGD) project or MRX. An overview of the MacKay River area was presented and the objectives of the project were outlined. The MacKay area is located 60 kilometres northwest of Fort McMurray and was Petro Canada's first commercial SAGD project. It has an estimated lifespan of 25 to 30 years. The MRX objectives are to ensure bitumen supply of 40,000 bbl/day at the central facility; to design injectors and producers that minimize liquid level build-up; and to optimize SOR by even steam chamber development. The intent of the project was to reduce logistics, drilling, and facilities costs. The presentation also discussed extended reach cost savings; rig utilization; geology; well design challenges; MRX planning and preparation; MRX directional planning; and liner running installation limits. It was concluded that in going forward, continued well design is important for configuring casing/tubing, slotting design, and cement integrity. figs.

  12. Defining in Classroom Activities.

    Science.gov (United States)

    Mariotti, Maria Alessandra; Fischbein, Efraim

    1997-01-01

    Discusses some aspects of the defining process in geometrical context in the reference frame of the theory of "figural concepts." Presents analysis of some examples taken from a teaching experiment at the sixth-grade level. Contains 30 references. (Author/ASK)

  13. MAC Security and Security Overhead Analysis in the IEEE 802.15.4 Wireless Sensor Networks

    Directory of Open Access Journals (Sweden)

    Sethi Sakshi

    2006-01-01

    Full Text Available Sensor networks have many applications. However, with limited resources such as computation capability and memory, they are vulnerable to many kinds of attacks. The IEEE 802.15.4 specification defines medium access control (MAC layer and physical layer for wireless sensor networks. In this paper, we propose a security overhead analysis for the MAC layer in the IEEE 802.15.4 wireless sensor networks. Furthermore, we survey security mechanisms defined in the specification including security objectives, security suites, security modes, encryption, authentication, and so forth. Then, security vulnerabilities and attacks are identified. Some security enhancements are proposed to improve security and to prevent these attacks such as same-nonce attack, denial-of-service attack, reply-protection attack, ACK attack, and so forth. Our results show that, for example, with 128-bit key length and 100 MIPS, encryption overhead is 10.28 s per block, and with 100 MIPS and 1500-byte payload, the encryption overhead is as high as 5782.5 s.

  14. Dolphin natures, human virtues: MacIntyre and ethical naturalism.

    Science.gov (United States)

    Glackin, Shane Nicholas

    2008-09-01

    Can biological facts explain human morality? Aristotelian 'virtue' ethics has traditionally assumed so. In recent years Alasdair MacIntyre has reintroduced a form of Aristotle's 'metaphysical biology' into his ethics. He argues that the ethological study of dependence and rationality in other species--dolphins in particular--sheds light on how those same traits in the typical lives of humans give rise to the moral virtues. However, some goal-oriented dolphin behaviour appears both dependent and rational in the precise manner which impresses MacIntyre, yet anything but ethically 'virtuous'. More damningly, dolphin ethologists consistently refuse to evaluate such behaviour in the manner MacIntyre claims is appropriate to moral judgement. In light of this, I argue that virtues--insofar as they name a biological or ethological category--do not name a morally significant one.

  15. An Energy Efficient MAC Proto col for Linear WSNs

    Institute of Scientific and Technical Information of China (English)

    DAI Guoyong; MIAO Chunyu; YING Kezhen; WANG Kai; CHEN Qingzhang

    2015-01-01

    Wireless sensor networks (WSNs) have been employed as an ideal solution in many applications for data gathering in harsh environment. Energy consumption is a key issue in wireless sensor networks since nodes are often battery operated. Medium access control (MAC) pro-tocol plays an important role in energy efficiency in wire-less sensor networks because nodes’ access to the shared medium is coordinated by the MAC layer. An energy ef-ficient MAC protocol is designed for data gathering in linear wireless sensor networks. In order to enhance the performance, when a source node transmits data to the sink, proper relay nodes are selected for forwarding data according to the energy consumption factor and residual energy balance factor. Some simulation experiments are conducted and the results show that, the proposed proto-col provides better energy efficiency and long lifetime than the existing DMAC protocol.

  16. Implementation of MAC by using Modified Vedic Multiplier

    Directory of Open Access Journals (Sweden)

    Sreelekshmi M. S.

    2013-09-01

    Full Text Available Multiplier Accumulator Unit (MAC is a part of Digital Signal Processors. The speed of MAC depends on the speed of multiplier. So by using an efficient Vedic multiplier which excels in terms of speed, power and area, the performance of MAC can be increased. For this fast method of multiplication based on ancient Indian Vedic mathematics is proposed in this paper. Among various method of multiplication in Vedic mathematics, Urdhva Tiryagbhyam is used and the multiplication is for 32 X 32 bits. Urdhva Tiryagbhyam is a general multiplication formula applicable to all cases of multiplication. Adder used is Carry Look Ahead adder. The proposed design shows improvement over carry save adder.

  17. Cognitive MAC Protocols for General Primary Network Models

    CERN Document Server

    Mehanna, Omar; Gamal, Hesham El

    2009-01-01

    We consider the design of cognitive Medium Access Control (MAC) protocols enabling a secondary (unlicensed) transmitter-receiver pair to communicate over the idle periods of a set of primary (licensed) channels. More specifically, we propose cognitive MAC protocols optimized for both slotted and un-slotted primary networks. For the slotted structure, the objective is to maximize the secondary throughput while maintaining synchronization between the secondary pair and not causing interference to the primary network. Our investigations differentiate between two sensing scenarios. In the first, the secondary transmitter is capable of sensing all the primary channels, whereas it senses only a subset of the primary channels in the second scenario. In both cases, we propose blind MAC protocols that efficiently learn the statistics of the primary traffic on-line and asymptotically achieve the throughput obtained when prior knowledge of primary traffic statistics is available. For the un-slotted structure, the object...

  18. Synthesizing Existing CSMA and TDMA Based MAC Protocols for VANETs.

    Science.gov (United States)

    Huang, Jiawei; Li, Qi; Zhong, Shaohua; Liu, Lianhai; Zhong, Ping; Wang, Jianxin; Ye, Jin

    2017-02-10

    Many Carrier Sense Multiple Access (CSMA) and Time Division Multiple Access (TDMA) based medium access control (MAC) protocols for vehicular ad hoc networks (VANETs) have been proposed recently. Contrary to the common perception that they are competitors, we argue that the underlying strategies used in these MAC protocols are complementary. Based on this insight, we design CTMAC, a MAC protocol that synthesizes existing strategies; namely, random accessing channel (used in CSMA-style protocols) and arbitral reserving channel (used in TDMA-based protocols). CTMAC swiftly changes its strategy according to the vehicle density, and its performance is better than the state-of-the-art protocols. We evaluate CTMAC using at-scale simulations. Our results show that CTMAC reduces the channel completion time and increases the network goodput by 45% for a wide range of application workloads and network settings.

  19. Office for iPad and Mac for dummies

    CERN Document Server

    Weverka, Peter

    2015-01-01

    The easy way to work with Office on your iPad or Mac Are you a Mac user who isn't accustomed to working with Microsoft Office? Consider this friendly guide your go-to reference! Written in plain English and packed with easy-to-follow, step-by-step instructions, Office for iPad and Mac For Dummies walks you through every facet of Office, from installing the software and opening files to working with Word, Excel, PowerPoint, and Outlook-and beyond. Plus, you'll discover how to manage files, share content and collaborate online through social media, and find help when you need it. Two things a

  20. SACRB-MAC: A High-Capacity MAC Protocol for Cognitive Radio Sensor Networks in Smart Grid.

    Science.gov (United States)

    Yang, Zhutian; Shi, Zhenguo; Jin, Chunlin

    2016-03-31

    The Cognitive Radio Sensor Network (CRSN) is considered as a viable solution to enhance various aspects of the electric power grid and to realize a smart grid. However, several challenges for CRSNs are generated due to the harsh wireless environment in a smart grid. As a result, throughput and reliability become critical issues. On the other hand, the spectrum aggregation technique is expected to play an important role in CRSNs in a smart grid. By using spectrum aggregation, the throughput of CRSNs can be improved efficiently, so as to address the unique challenges of CRSNs in a smart grid. In this regard, we proposed Spectrum Aggregation Cognitive Receiver-Based MAC (SACRB-MAC), which employs the spectrum aggregation technique to improve the throughput performance of CRSNs in a smart grid. Moreover, SACRB-MAC is a receiver-based MAC protocol, which can provide a good reliability performance. Analytical and simulation results demonstrate that SACRB-MAC is a promising solution for CRSNs in a smart grid.

  1. SACRB-MAC: A High-Capacity MAC Protocol for Cognitive Radio Sensor Networks in Smart Grid

    Directory of Open Access Journals (Sweden)

    Zhutian Yang

    2016-03-01

    Full Text Available The Cognitive Radio Sensor Network (CRSN is considered as a viable solution to enhance various aspects of the electric power grid and to realize a smart grid. However, several challenges for CRSNs are generated due to the harsh wireless environment in a smart grid. As a result, throughput and reliability become critical issues. On the other hand, the spectrum aggregation technique is expected to play an important role in CRSNs in a smart grid. By using spectrum aggregation, the throughput of CRSNs can be improved efficiently, so as to address the unique challenges of CRSNs in a smart grid. In this regard, we proposed Spectrum Aggregation Cognitive Receiver-Based MAC (SACRB-MAC, which employs the spectrum aggregation technique to improve the throughput performance of CRSNs in a smart grid. Moreover, SACRB-MAC is a receiver-based MAC protocol, which can provide a good reliability performance. Analytical and simulation results demonstrate that SACRB-MAC is a promising solution for CRSNs in a smart grid.

  2. Functional classifications for cerebral palsy: correlations between the gross motor function classification system (GMFCS), the manual ability classification system (MACS) and the communication function classification system (CFCS).

    Science.gov (United States)

    Compagnone, Eliana; Maniglio, Jlenia; Camposeo, Serena; Vespino, Teresa; Losito, Luciana; De Rinaldis, Marta; Gennaro, Leonarda; Trabacca, Antonio

    2014-11-01

    This study aimed to investigate a possible correlation between the gross motor function classification system-expanded and revised (GMFCS-E&R), the manual abilities classification system (MACS) and the communication function classification system (CFCS) functional levels in children with cerebral palsy (CP) by CP subtype. It was also geared to verify whether there is a correlation between these classification systems and intellectual functioning (IF) and parental socio-economic status (SES). A total of 87 children (47 males and 40 females, age range 4-18 years, mean age 8.9±4.2) were included in the study. A strong correlation was found between the three classifications: Level V of the GMFCS-E&R corresponds to Level V of the MACS (rs=0.67, p=0.001); the same relationship was found for the CFCS and the MACS (rs=0.73, pfunctional disability profile were strong or moderate (GMFCS and IQ: rs=0.66, p=0.001; MACS and IQ: rs=0.58, p=0.001; CFCS and MACS: rs=0.65, p=0.001). The Kruskal-Wallis test was used to determine if there were differences between the GMFCS-E&R, the CFCS and the MACS by CP type. CP types showed different scores for the IQ level (Chi-square=8.59, df=2, p=0.014), the GMFCS-E&R (Chi-square=36.46, df=2, pfunctional classifications (GMFCS-E&R, CFCS and MACS) complement each other to provide a better description of the functional profile of CP. The systematic evaluation of the IQ can provide useful information about a possible future outcome for every functional level. The SES does not appear to affect functional profiles.

  3. MacSyFinder: a program to mine genomes for molecular systems with an application to CRISPR-Cas systems.

    Directory of Open Access Journals (Sweden)

    Sophie S Abby

    Full Text Available Biologists often wish to use their knowledge on a few experimental models of a given molecular system to identify homologs in genomic data. We developed a generic tool for this purpose.Macromolecular System Finder (MacSyFinder provides a flexible framework to model the properties of molecular systems (cellular machinery or pathway including their components, evolutionary associations with other systems and genetic architecture. Modelled features also include functional analogs, and the multiple uses of a same component by different systems. Models are used to search for molecular systems in complete genomes or in unstructured data like metagenomes. The components of the systems are searched by sequence similarity using Hidden Markov model (HMM protein profiles. The assignment of hits to a given system is decided based on compliance with the content and organization of the system model. A graphical interface, MacSyView, facilitates the analysis of the results by showing overviews of component content and genomic context. To exemplify the use of MacSyFinder we built models to detect and class CRISPR-Cas systems following a previously established classification. We show that MacSyFinder allows to easily define an accurate "Cas-finder" using publicly available protein profiles.MacSyFinder is a standalone application implemented in Python. It requires Python 2.7, Hmmer and makeblastdb (version 2.2.28 or higher. It is freely available with its source code under a GPLv3 license at https://github.com/gem-pasteur/macsyfinder. It is compatible with all platforms supporting Python and Hmmer/makeblastdb. The "Cas-finder" (models and HMM profiles is distributed as a compressed tarball archive as Supporting Information.

  4. AMPA receptor competitive antagonism reduces halothane MAC in rats.

    Science.gov (United States)

    McFarlane, C; Warner, D S; Todd, M M; Nordholm, L

    1992-12-01

    Various subtypes of receptors have been identified for glutamate, an excitatory neurotransmitter. Previous studies have shown that antagonism of glutamate at the NMDA receptors reduces minimum alveolar concentration (MAC) for volatile anesthetics. NBQX (2,3-dihydroxy-6-nitro-7-sulfamoyl-benzo(f)quinoxaline) is a selective antagonist at the glutamatergic AMPA receptor. The purpose of this experiment was to determine whether AMPA receptor antagonism influences halothane MAC in the rat. Sprague-Dawley rats were anesthetized with halothane in 50% O2/balance N2, tracheally intubated and the lungs were mechanically ventilated. Increasing doses of NBQX were intravenously infused in three groups while the control group was infused with vehicle (D5W). Halothane MAC was then determined by the tail-clamp method. Halothane MAC was log-linearly related to plasma NBQX concentrations (MAC = 0.125 (In plasma concentration NBQX) + 1.035, r2 = 0.77). A maximal 58% reduction of halothane MAC was achieved with an NBQX loading dose of 42 mg/kg followed by a continuous infusion rate of 36 mg x kg-1 x h-1 (control = 1.02 +/- 0.07%; NBQX = 0.43 +/- 0.12%; P awake rats were randomly assigned to groups based on the dose of NBQX infused. Pa(CO2) and mean arterial pressure were measured at time 0 and at 5 and 30 min after start of NBQX infusion. The infusion was then stopped. Time until recovery of the righting reflex was recorded.(ABSTRACT TRUNCATED AT 250 WORDS)

  5. Alasdair MacIntyre: relatividad conceptual, tomismo y liberalismo

    Directory of Open Access Journals (Sweden)

    Carlos Isler S.

    2011-01-01

    Full Text Available Influenciado por Thomas Kuhn, Alasdair MacIntyre presenta una teoría conceptualmente relativista sobre las tradiciones de investigación, la cual pretende no sólo describir la estructura de las distintas tradiciones, sino también encontrar un principioque permita resolver las disputas entre ellas. Se expone esta teoría y se analiza su compatibilidad con el tomismo, tradición a la que MacIntyre dice pertenecer, y con el liberalismo, tradición a la que critica con vigor.

  6. Mac Lane method in the investigation of magnetic translation groups

    OpenAIRE

    Florek, Wojciech

    1998-01-01

    Central extensions of the three-dimensional translation group T=Z^3 by the unitary group U(1) (a group of factors) are considered within the frame of the Mac~Lane method. All nonzero vectors t in T are considered to be generators of T. This choice leads to very illustrative relations between the Mac~Lane method and Zak's approach to magnetic translation groups. It is shown that factor systems introduced by Zak and Brown can be realized only for the unitary group U(1) and for some of its finit...

  7. Plasma IL-8 and IL-6 levels can be used to define a group with low risk of septicaemia among cancer patients with fever and neutropenia

    NARCIS (Netherlands)

    de Bont, ESJM; Vellenga, E; Swaanenburg, JCJM; Fidler, [No Value; Visser-van Brummen, PJ; Kamps, WA

    1999-01-01

    The standard therapy for patients with fever and chemotherapy-related neutropenia is hospitalization and infusion of broad-spectrum antibiotics. Early discharge of a defined group of patients at low risk for septicaemia would be of great advantage for these patients. Ih this study plasma

  8. Plasma IL-8 and IL-6 levels can be used to define a group with low risk of septicaemia among cancer patients with fever and neutropenia

    NARCIS (Netherlands)

    de Bont, ESJM; Vellenga, E; Swaanenburg, JCJM; Fidler, [No Value; Visser-van Brummen, PJ; Kamps, WA

    1999-01-01

    The standard therapy for patients with fever and chemotherapy-related neutropenia is hospitalization and infusion of broad-spectrum antibiotics. Early discharge of a defined group of patients at low risk for septicaemia would be of great advantage for these patients. Ih this study plasma interleukin

  9. Directional Medium Access Control (MAC Protocols in Wireless Ad Hoc and Sensor Networks: A Survey

    Directory of Open Access Journals (Sweden)

    David Tung Chong Wong

    2015-06-01

    Full Text Available This survey paper presents the state-of-the-art directional medium access control (MAC protocols in wireless ad hoc and sensor networks (WAHSNs. The key benefits of directional antennas over omni-directional antennas are longer communication range, less multipath interference, more spatial reuse, more secure communications, higher throughput and reduced latency. However, directional antennas lead to single-/multi-channel directional hidden/exposed terminals, deafness and neighborhood, head-of-line blocking, and MAC-layer capture which need to be overcome. Addressing these problems and benefits for directional antennas to MAC protocols leads to many classes of directional MAC protocols in WAHSNs. These classes of directional MAC protocols presented in this survey paper include single-channel, multi-channel, cooperative and cognitive directional MACs. Single-channel directional MAC protocols can be classified as contention-based or non-contention-based or hybrid-based, while multi-channel directional MAC protocols commonly use a common control channel for control packets/tones and one or more data channels for directional data transmissions. Cooperative directional MAC protocols improve throughput in WAHSNs via directional multi-rate/single-relay/multiple-relay/two frequency channels/polarization, while cognitive directional MAC protocols leverage on conventional directional MAC protocols with new twists to address dynamic spectrum access. All of these directional MAC protocols are the pillars for the design of future directional MAC protocols in WAHSNs.

  10. Link-layer jamming attacks on S-MAC

    NARCIS (Netherlands)

    Law, Yee Wei; Hartel, Pieter; Hartog, den Jerry; Havinga, Paul

    2005-01-01

    We argue that among denial-of-service (DoS) attacks, link-layer jamming is a more attractive option to attackers than radio jamming is. By exploiting the semantics of the link-layer protocol (aka MAC protocol), an attacker can achieve better efficiency than blindly jamming the radio signals alone. W

  11. Listening, Looking, and Learning with MacLang.

    Science.gov (United States)

    Frommer, Judith

    1989-01-01

    Describes how the capabilities of the MacLang authoring system allow foreign language teachers to develop computer-assisted instruction that meets the listening skill objectives of foreign language courses. Examples are given of the use of audio and video interfaces that facilitate listening comprehension. (Author/CB)

  12. Beamforming in Ad Hoc Networks: MAC Design and Performance Modeling

    Directory of Open Access Journals (Sweden)

    Khalil Fakih

    2009-01-01

    Full Text Available We examine in this paper the benefits of beamforming techniques in ad hoc networks. We first devise a novel MAC paradigm for ad hoc networks when using these techniques in multipath fading environment. In such networks, the use of conventional directional antennas does not necessarily improve the system performance. On the other hand, the exploitation of the potential benefits of smart antenna systems and especially beamforming techniques needs a prior knowledge of the physical channel. Our proposition performs jointly channel estimation and radio resource sharing. We validate the fruitfulness of the proposed MAC and we evaluate the effects of the channel estimation on the network performance. We then present an accurate analytical model for the performance of IEEE 802.11 MAC protocol. We extend the latter model, by introducing the fading probability, to derive the saturation throughput for our proposed MAC when the simplest beamforming strategy is used in real multipath fading ad hoc networks. Finally, numerical results validate our proposition.

  13. God, Sport Philosophy, Kinesiology: A MacIntyrean Examination

    Science.gov (United States)

    Twietmeyer, Gregg

    2015-01-01

    Sport philosophy is in crisis. This subdiscipline of kinesiology garners little to no respect and few tenure track lines in kinesiology departments. Why is this the case? Why isn't philosophy held in greater esteem? Is it possible that philosopher Alasdair MacIntyre's (2009) diagnosis found in "God, Philosophy, Universities" could…

  14. MAC Support for High Density Wireless Sensor Networks

    NARCIS (Netherlands)

    Taddia, C.; Meratnia, Nirvana; van Hoesel, L.F.W.; Mazzini, G.; Havinga, Paul J.M.

    Large scale and high density networks of tiny sensor nodes offer promising solutions for event detection and actuating applications. In this paper we address the effect of high density of wireless sensor network performance with a specific MAC protocol, the Lightweight Medium Access Control (LMAC).

  15. God, Sport Philosophy, Kinesiology: A MacIntyrean Examination

    Science.gov (United States)

    Twietmeyer, Gregg

    2015-01-01

    Sport philosophy is in crisis. This subdiscipline of kinesiology garners little to no respect and few tenure track lines in kinesiology departments. Why is this the case? Why isn't philosophy held in greater esteem? Is it possible that philosopher Alasdair MacIntyre's (2009) diagnosis found in "God, Philosophy, Universities" could…

  16. MAC inhibitors antagonize the pro-apoptotic effects of tBid and disassemble Bax / Bak oligomers.

    Science.gov (United States)

    Peixoto, Pablo M; Teijido, Oscar; Mirzalieva, Oygul; Dejean, Laurent M; Pavlov, Evgeny V; Antonsson, Bruno; Kinnally, Kathleen W

    2017-02-01

    Mitochondrial Apoptotic Channel inhibitors or iMACs are di-bromocarbazole derivatives with anti-apoptotic function which have been tested and validated in several mouse models of brain injury and neurodegeneration. Owing to the increased therapeutic potential of these compounds, we sought to expand our knowledge of their mechanism of action. We investigated the kinetics of MAC inhibition in mitochondria from wild type, Bak, and Bax knockout cell lines using patch clamp electrophysiology, fluorescence microscopy, ELISA, and semiquantitative western blot analyses. Our results show that iMACs work through at least two mechanisms: 1) by blocking relocation of the cytoplasmic Bax protein to mitochondria and 2) by disassembling Bax and Bak oligomers in the mitochondrial outer membrane. iMACs exert comparable effects on channel conductance of Bax or Bak and similarly affect cytochrome c release from Bax or Bak-containing mitochondria. Interestingly, wild type mitochondria were more susceptible to inhibition than the Bak or Bax knockouts. Western blot analysis showed that wild type mitochondria had lower steady state levels of Bak in the absence of apoptotic stimulation.

  17. Roles of Mac-1 and glycoprotein IIb/IIIa integrins in leukocyte-platelet aggregate formation: stabilization by Mac-1 and inhibition by GpIIb/IIIa blockers.

    Science.gov (United States)

    Patko, Zsofia; Csaszar, Albert; Acsady, Gyorgy; Peter, Karlheinz; Schwarz, Meike

    2012-01-01

    Circulating platelet-leukocyte hetero-aggregates play an important role in acute cardiovascular events and hypersensitivity reactions. The association involves the receptor families of selectins and integrin. The objective of this study was to investigate the role of CD11b/CD18 integrin (Mac-1) in hetero-aggregate formation and search for a counter-receptor on platelets ready to interact with Mac-1. As a model of leukocytes, Mac-1 presenting Chinese hamster ovary (CHO) cells were used to evaluate the role of Mac-1 in hetero-aggregate formation. The amount of CHO cell-bound active and inactive platelets was measured by flow cytometry, while the counter-receptors on platelets were identified via using blocking antibodies. We observed significant platelet adhesion on Mac-1-bearing cells when platelet-rich plasma or activated platelets were present. Inactive platelets did not adhere to Mac-1-bearing cells. Addition of fibrinogen, a ligand of Mac-1 significantly increased platelet binding. CD40L was demonstrated to act similarly on Mac-1. Inhibition of platelet GpIIb/IIIa completely abolished CHO cell-platelet aggregation. In our study, we have shown for the first time that Mac-1 mediates the formation of hetero-aggregates without selectin tethering when Mac-1 ligands such as fibrinogen or CD40L are present and blockers of platelet GpIIb/IIIa are able to diminish this interaction.

  18. Pyrogen testing of lipid-based TPN using Mono Mac 6 monocyte cell line and DELFIA

    DEFF Research Database (Denmark)

    Moesby, Lise; Hansen, E W; Christensen, J D

    1997-01-01

    Measurement of lipopolysaccharide (LPS) induced interleukin-6 (IL-6) secretion in Mono Mac 6 cells.......Measurement of lipopolysaccharide (LPS) induced interleukin-6 (IL-6) secretion in Mono Mac 6 cells....

  19. Systemic distribution of blood flow in swine while awake and during 1.0 and 1.5 MAC isoflurane anesthesia with or without 50% nitrous oxide.

    Science.gov (United States)

    Lundeen, G; Manohar, M; Parks, C

    1983-05-01

    To examine the effects of isoflurane on systemic distribution of cardiac output, organ/tissue blood flow was measured in 11 isocapnic pigs using 15-micrometer diameter radionuclide-labeled microspheres injected into the left atrium. Measurements were made on each pig during five of the following six conditions; awake (control); 1.0 MAC (1.45% end-tidal)isoflurane anesthesia; 1.5 MAC (2.18% end-tidal) isoflurane anesthesia; 0.95% end-tidal isoflurane and 50% N2O anesthesia equivalent to 1.0 MAC; 1.68% end-tidal isoflurane and 50% N2O anesthesia equivalent to 1.5 MAC; and 50% N2O administration. The order of anesthetized steps was randomized. A period of 60 min was interposed between anesthetized steps to allow pigs to recover towards control values. Mean aortic pressure decreased in a dose-related manner during isoflurane anesthesia, whereas cardiac output decreased only during 1.5 MAC isoflurane anesthesia and heart rate remained unchanged. The addition of N2O attenuated the hypotensive effects of isoflurane and cardiac output was maintained near control values because of increased heart rate. Brain blood flow increased in a dose-dependent manner with isoflurane anesthesia, but myocardial blood flow exhibited a dose-related decrease. The addition of 50% N2O to maintain the same total MAC anesthesia resulted in a larger increase in brain blood flow especially at 1.5 MAC, while myocardial blood flow was maintained near control value. Rate-pressure product and myocardial blood flow at 1.5 MAC anesthesia were higher when N2O was used with isoflurane. While blood flow and fraction of cardiac output going to the adrenal glands were unaltered during isoflurane-N2O anesthesia, blood flow increased at 1.5 MAC isoflurane anesthesia. Splenic blood flow and splenic fraction of cardiac output were increased at both MAC levels of isoflurane as well as isoflurane-N2O anesthesia whereas blood flow to the stomach, small intestine, diaphragm, skeletal muscle, and adipose tissue

  20. MAC: identifying and correcting annotation for multi-nucleotide variations.

    Science.gov (United States)

    Wei, Lei; Liu, Lu T; Conroy, Jacob R; Hu, Qiang; Conroy, Jeffrey M; Morrison, Carl D; Johnson, Candace S; Wang, Jianmin; Liu, Song

    2015-08-01

    Next-Generation Sequencing (NGS) technologies have rapidly advanced our understanding of human variation in cancer. To accurately translate the raw sequencing data into practical knowledge, annotation tools, algorithms and pipelines must be developed that keep pace with the rapidly evolving technology. Currently, a challenge exists in accurately annotating multi-nucleotide variants (MNVs). These tandem substitutions, when affecting multiple nucleotides within a single protein codon of a gene, result in a translated amino acid involving all nucleotides in that codon. Most existing variant callers report a MNV as individual single-nucleotide variants (SNVs), often resulting in multiple triplet codon sequences and incorrect amino acid predictions. To correct potentially misannotated MNVs among reported SNVs, a primary challenge resides in haplotype phasing which is to determine whether the neighboring SNVs are co-located on the same chromosome. Here we describe MAC (Multi-Nucleotide Variant Annotation Corrector), an integrative pipeline developed to correct potentially mis-annotated MNVs. MAC was designed as an application that only requires a SNV file and the matching BAM file as data inputs. Using an example data set containing 3024 SNVs and the corresponding whole-genome sequencing BAM files, we show that MAC identified eight potentially mis-annotated SNVs, and accurately updated the amino acid predictions for seven of the variant calls. MAC can identify and correct amino acid predictions that result from MNVs affecting multiple nucleotides within a single protein codon, which cannot be handled by most existing SNV-based variant pipelines. The MAC software is freely available and represents a useful tool for the accurate translation of genomic sequence to protein function.

  1. Generation of MAC waves by convection in Earth's core

    Science.gov (United States)

    Jaupart, Etienne; Buffett, Bruce

    2017-05-01

    Convection in Earth's core is a viable mechanism for generating MAC waves when the top of the core is stably stratified. We quantify the generation mechanism by extending the physical description of MAC waves to include a source term due to buoyancy forces in the convecting part of the core. Solutions for the forced motion are obtained using a Green's function, which is constructed from the eigenfunctions for the unforced motion. When the source term is evaluated using the output of a numerical geodynamo model, the largest excitation occurs at even spherical harmonic degrees, corresponding to waves with symmetric azimuthal flow about the equator. We also find that the magnitude of the source term decreases at periods shorter than about 60 yr. As a result most of the wave generation is confined to waves with periods of 60 yr or longer. Quantitative predictions for the wave amplitudes depend on the projection of the source term into the eigenfunction of the waves. Strong stratification limits the penetration of density anomalies into the stratified layer, which means that the source term is confined to the lowermost part of the layer. Overtones of MAC waves with large amplitudes in the lower part of the stratified layer are more effectively generated by convection, even though these waves are heavily damped by magnetic diffusion. Generation of MAC waves by convection establishes a physical link between observable wave motion and deeper convective processes. Detection of changes in the amplitude and phase of MAC waves would constrain the generation processes and offer insights into the nature of the convection.

  2. 42 CFR 405.1110 - MAC reviews on its own motion.

    Science.gov (United States)

    2010-10-01

    ... 42 Public Health 2 2010-10-01 2010-10-01 false MAC reviews on its own motion. 405.1110 Section 405....1110 MAC reviews on its own motion. (a) General rule. The MAC may decide on its own motion to review a decision or dismissal issued by an ALJ. CMS or any of its contractors may refer a case to the MAC for it to...

  3. Minimum Alveolar Concentration for Blunting Adrenergic Responses (MAC-BAR) of Sevoflurane in Dogs

    OpenAIRE

    YAMASHITA, Kazuto; FURUKAWA, Erika; ITAMI, Takaharu; ISHIZUKA, Tomohito; TAMURA, Jun; MIYOSHI, Kenjirou

    2012-01-01

    It is well known that heart rate or arterial blood pressure may increase in response to surgical stimulation despite the absence of a purposeful movement. However, there is limited information regarding anesthetic requirement for blunting adrenergic response in dogs. This study was designed to compare the minimum alveolar concentrations of sevoflurane required to prevent autonomic response (MAC-BAR) and purposeful movement (MAC) in dogs. Sevoflurane MAC-BAR and MAC were determined in 5 beagle...

  4. A Reconfigurable Hybrid Architecture for HomePNA3.1/ Ethernet MAC

    Directory of Open Access Journals (Sweden)

    Mohammad Khalily Dermany

    2011-12-01

    Full Text Available With the growing demands of home networking, the existing networking technologies are not able to satisfy user expectations any more. HomePNA (Home Phoneline Networking Alliance is a solution for having high bandwidth without new cabling.In this paper, we propose a new reconfigurable hybrid architecture for HomePNA3.0. We implement the architecture in behavioural level using VHDL language. Our implementation was able to have HomePNA3.1 and Ethernet MACs together. The system synthesis show that our implementation decrease number of logical element by 32%.

  5. MDS-Mac: a scheduled MAC for localization, time-synchronisation and communication in underwater acoustic networks

    NARCIS (Netherlands)

    Kleunen, van Wouter; Meratnia, Nirvana; Havinga, Paul J.M.

    2012-01-01

    In this paper we describe a design for an underwater MAC protocol which combines localization, time-synchronisation and communication. This protocol is designed for small-scale clustered networks in which all nodes are able to ommunicate with each other. We consider an integrated design of localizat

  6. TR-MAC: an energy-efficient MAC protocol for wireless sensor networks exploiting noise-based transmitted reference modulation

    NARCIS (Netherlands)

    Morshed, S.; Dimitrova, D.C.; Brogle, M.; Braun, T.; Heijenk, Gerhard J.

    Energy-constrained behavior of sensor nodes is one of the most important criteria for successful deployment of wireless sensor net- works. The medium access control (MAC) protocol determines the time a sensor node transceiver spends listening or transmitting, and hence the energy consumption of the

  7. CoR-MAC: Contention over Reservation MAC Protocol for Time-Critical Services in Wireless Body Area Sensor Networks.

    Science.gov (United States)

    Yu, Jeongseok; Park, Laihyuk; Park, Junho; Cho, Sungrae; Keum, Changsup

    2016-05-09

    Reserving time slots for urgent data, such as life-critical information, seems to be very attractive to guarantee their deadline requirements in wireless body area sensor networks (WBASNs). On the other hand, this reservation imposes a negative impact on performance for the utilization of a channel. This paper proposes a new channel access scheme referred to as the contention over reservation MAC (CoR-MAC) protocol for time-critical services in wireless body area sensor networks. CoR-MAC uses the dual reservation; if the reserved time slots are known to be vacant, other nodes can access the time slots by contention-based reservation to maximize the utilization of a channel and decrease the delay of the data. To measure the effectiveness of the proposed scheme against IEEE 802.15.4 and IEEE 802.15.6, we evaluated their performances with various performance indexes. The CoR-MAC showed 50% to 850% performance improvement in terms of the delay of urgent and time-critical data according to the number of nodes.

  8. Library Signage: Applications for the Apple Macintosh and MacPaint.

    Science.gov (United States)

    Diskin, Jill A.; FitzGerald, Patricia

    1984-01-01

    Describes specific applications of the Macintosh computer at Carnegie-Mellon University Libraries, where MacPaint was used as a flexible, easy to use, and powerful tool to produce informational, instructional, and promotional signage. Profiles of system hardware and software, an evaluation of the computer program MacPaint, and MacPaint signage…

  9. 42 CFR 405.1050 - Removal of a hearing request from an ALJ to the MAC.

    Science.gov (United States)

    2010-10-01

    ... 42 Public Health 2 2010-10-01 2010-10-01 false Removal of a hearing request from an ALJ to the MAC... Removal of a hearing request from an ALJ to the MAC. If a request for hearing is pending before an ALJ, the MAC may assume responsibility for holding a hearing by requesting that the ALJ send the hearing...

  10. 42 CFR 405.1108 - MAC actions when request for review or escalation is filed.

    Science.gov (United States)

    2010-10-01

    ... 42 Public Health 2 2010-10-01 2010-10-01 false MAC actions when request for review or escalation...) Medicare Appeals Council Review § 405.1108 MAC actions when request for review or escalation is filed. (a) Except as specified in paragraphs (c) and (d) of this section, when a party requests that the MAC review...

  11. 42 CFR 405.1102 - Request for MAC review when ALJ issues decision or dismissal.

    Science.gov (United States)

    2010-10-01

    ... 42 Public Health 2 2010-10-01 2010-10-01 false Request for MAC review when ALJ issues decision or...) Medicare Appeals Council Review § 405.1102 Request for MAC review when ALJ issues decision or dismissal. (a)(1) A party to the ALJ hearing may request a MAC review if the party files a written request for...

  12. IgG protease Mac/IdeS is not essential for phagocyte resistance or mouse virulence of M1T1 group A Streptococcus.

    Science.gov (United States)

    Okumura, Cheryl Y M; Anderson, Ericka L; Döhrmann, Simon; Tran, Dan N; Olson, Joshua; von Pawel-Rammingen, Ulrich; Nizet, Victor

    2013-07-30

    The Mac/IdeS protein of group A Streptococcus (GAS) is a secreted cysteine protease with cleavage specificity for IgG and is highly expressed in the GAS serotype M1T1 clone, which is the serotype most frequently isolated from patients with life-threatening invasive infections. While studies of Mac/IdeS with recombinant protein have shown that the protein can potentially prevent opsonophagocytosis of GAS by neutrophils, the role of the protein in immune evasion as physiologically produced by the living organism has not been studied. Here we examined the contribution of Mac/IdeS to invasive GAS disease by generating a mutant lacking Mac/IdeS in the hyperinvasive M1T1 background. While Mac/IdeS was highly expressed and proteolytically active in the hyperinvasive strain, elimination of the bacterial protease did not significantly influence GAS phagocytic uptake, oxidative-burst induction, cathelicidin sensitivity, resistance to neutrophil or macrophage killing, or pathogenicity in pre- or postimmune mouse infectious challenges. We conclude that in the highly virulent M1T1 background, Mac/IdeS is not essential for either phagocyte resistance or virulence. Given the conservation of Mac/IdeS and homologues across GAS strains, it is possible that Mac/IdeS serves another important function in GAS ecology or contributes to virulence in other strain backgrounds. Group A Streptococcus (GAS) causes human infections ranging from strep throat to life-threatening conditions such as flesh-eating disease and toxic shock syndrome. Common disease-associated clones of GAS can cause both mild and severe infections because of a characteristic mutation and subsequent change in the expression of several genes that develops under host immune selection. One of these genes encodes Mac/IdeS, a protease that has been shown to cleave antibodies important to the immune defense system. In this study, we found that while Mac/IdeS is highly expressed in hypervirulent GAS, it does not significantly

  13. The minimum alveolar concentration (MAC) and hemodynamic effects of halothane, isoflurane, and sevoflurane in newborn swine.

    Science.gov (United States)

    Lerman, J; Oyston, J P; Gallagher, T M; Miyasaka, K; Volgyesi, G A; Burrows, F A

    1990-10-01

    To determine the minimum alveolar concentration (MAC) and hemodynamic responses to halothane, isoflurane, and sevoflurane in newborn swine, 36 fasting swine 4-10 days of age were anesthetized with one of the three volatile anesthetics in 100% oxygen. MAC was determined for each swine. Carotid artery and internal jugular catheters were inserted and each swine was allowed to recover for 48 h. After recovery, heart rate (HR), systemic systolic arterial pressure (SAP), and cardiac index (CI) were measured awake and then at 0.5, 1.0, and 1.5 MAC of the designated anesthetic in random sequence. The (mean +/- SD) MAC for halothane was 0.90 +/- 0.12%; the MAC for isoflurane was 1.48 +/- 0.21%; and the MAC for sevoflurane was 2.12 +/- 0.39%. Awake (mean +/- SD) measurements of HR, SAP, and CI did not differ significantly among the three groups. Compared to the awake HR, the mean HR decreased 35% at 1.5 MAC halothane (P less than 0.001), 19% at 1.5 MAC isoflurane (P less than 0.005), and 31% at 1.5 MAC sevoflurane (P less than 0.005). Compared to awake SAP, mean SAP measurements decreased 46% at 1.5 MAC halothane (P less than 0.001), 43% at 1.5 MAC isoflurane (P less than 0.001), and 36% at 1.5 MAC sevoflurane (P less than 0.005). Mean SAP at 1.0 and 1.5 MAC halothane and isoflurane were significantly less than those measured at equipotent concentrations of sevoflurane (P less than 0.005). Compared to awake CI, mean CI measurements decreased 53% at 1.5 MAC halothane (P less than 0.001) and 43% at 1.5 MAC isoflurane (P less than 0.005).(ABSTRACT TRUNCATED AT 250 WORDS)

  14. MAC-awake of isoflurane, enflurane and halothane evaluated by slow and fast alveolar washout.

    Science.gov (United States)

    Gaumann, D M; Mustaki, J P; Tassonyi, E

    1992-01-01

    End-tidal anaesthetic concentrations at first eye opening in response to a verbal command during recovery from anaesthesia (MAC-awake), were measured for isoflurane (n = 16), enflurane (n = 16) and halothane (n = 14). MAC-awake was measured during either slow or fast alveolar washout. Slow washout was obtained by decreasing anaesthetic concentrations in predetermined steps of 15 min, assuming equilibration between brain and alveolar partial pressures. Fast alveolar washout was obtained by discontinuation of the inhalation anaesthetic, which had been maintained at 1 MAC for at least 15 min. Mean MAC-awake obtained with slow alveolar washout was similar for isoflurane (0.25 (SD 0.03) MAC), and enflurane (0.27 (0.04) MAC) and significantly greater than values obtained by fast alveolar washout (isoflurane: 0.19 (0.03) MAC; enflurane: 0.20 (0.03) MAC). The MAC-awake of isoflurane and enflurane was significantly less than that of halothane, which was 0.59 (0.10) MAC as evaluated by the slow and 0.50 (0.05) MAC as evaluated by the fast alveolar washout method. Recovery time from anaesthesia with fast alveolar washout was 8.8 (4.0) min for halothane, which was not different from isoflurane (15 (2.5) min), but significantly shorter than for enflurane (22 (10) min), reflecting differences in the anaesthetic concentration gradient between MAC and MAC-awake values. These data do not support the hypothesis of a uniform ratio between MAC and MAC-awake values.

  15. A comparison of the C-MAC video laryngoscope to the Macintosh direct laryngoscope for intubation in the emergency department.

    Science.gov (United States)

    Sakles, John C; Mosier, Jarrod; Chiu, Stephen; Cosentino, Mari; Kalin, Leah

    2012-12-01

    We determine the proportion of successful intubations with the C-MAC video laryngoscope (C-MAC) compared with the direct laryngoscope in emergency department (ED) intubations. This was a retrospective analysis of prospectively collected data entered into a continuous quality improvement database during a 28-month period in an academic ED. After each intubation, the operator completed a standardized data form evaluating multiple aspects of the intubation, including patient demographics, indication for intubation, device(s) used, reason for device selection, difficult airway characteristics, number of attempts, and outcome of each attempt. Intubation was considered ultimately successful if the endotracheal tube was correctly inserted into the trachea with the initial device. An attempt was defined as insertion of the device into the mouth regardless of whether there was an attempt to pass the tube. The primary outcome measure was ultimate success. Secondary outcome measures were first-attempt success, Cormack-Lehane view, and esophageal intubation. Multivariate logistic regression analyses, with the inclusion of a propensity score, were performed for the outcome variables ultimate success and first-attempt success. During the 28-month study period, 750 intubations were performed with either the C-MAC with a size 3 or 4 blade or a direct laryngoscope with a Macintosh size 3 or 4 blade. Of these, 255 were performed with the C-MAC as the initial device and 495 with a Macintosh direct laryngoscope as the initial device. The C-MAC resulted in successful intubation in 248 of 255 cases (97.3%; 95% confidence interval [CI] 94.4% to 98.9%). A direct laryngoscope resulted in successful intubation in 418 of 495 cases (84.4%; 95% CI 81.0% to 87.5%). In the multivariate regression model, with a propensity score included, the C-MAC was positively predictive of ultimate success (odds ratio 12.7; 95% CI 4.1 to 38.8) and first-attempt success (odds ratio 2.2; 95% CI 1.2 to 3.8). When

  16. Distinguishing and Second-Preimage Attacks on CBC-Like MACs

    Science.gov (United States)

    Jia, Keting; Wang, Xiaoyun; Yuan, Zheng; Xu, Guangwu

    This paper first presents a new distinguishing attack on the CBC-MAC structure based on block ciphers in cipher block chaining (CBC) mode. This attack detects a CBC-like MAC from random functions. The second result of this paper is a second-preimage attack on the CBC-MAC, which is an extension of the attack of Brincat and Mitchell. The attack also covers MT-MAC, PMAC and MACs with three-key enciphered CBC mode. Instead of exhaustive search, both types of attacks are of birthday attack complexity.

  17. Magnetic activated cell sorting (MACS): utility in assisted reproduction.

    Science.gov (United States)

    Makker, Kartikeya; Agarwal, Ashok; Sharma, Rakesh K

    2008-07-01

    Assisted reproductive techniques (ART) have now been extensively incorporated in the management of infertile couples. But even after rapid methodological and technological advances the success rates of these procedures have been below expectations. This has led to development of many sperm preparation protocols to obtain an ideal semen sample for artificial reproduction. Sperm apoptosis has been heavily linked to failures in reproductive techniques. One of the earliest changes shown by apoptotic spermatozoa is externalization of phosphatidyl serine. Magnetic activated cell sorting (MACS) is a novel sperm preparation technique that separates apoptotic and non-apoptotic spermatozoa based on the expression of phosphatidylserine. This has led to the incorporation of MACS as a sperm preparation technique. The review highlights the principle and mechanism of this novel technique and enumerates its advantages as a sperm preparation technique. Its utility in ART as an efficient tool for sperm recovery and its application in cryopreservation of semen samples is also explained.

  18. On the Development of Low Power MAC Protocol for WBANs

    CERN Document Server

    Ullah, Sana; Kwak, Kyung Sup

    2009-01-01

    Current advances in wireless communication, microelectronics, semiconductor technologies, and intelligent sensors have contributed to the development of unobtrusive WBANs. These networks provide long term health monitoring of patients without any constraint in their normal activities. Traditional MAC protocols do not accommodate the assorted WBAN traffic requirements in a power efficient manner. In this paper, we present a brief discussion on the development process of a low power MAC protocol for WBANs. We observe the behavior of a beacon-enabled IEEE 802.15.4 for on-body sensor networks. We further propose a low power technique called traffic based wakeup mechanism for a WBAN that exploits the traffic patterns of the BAN Nodes to ensure power efficient and reliable communication.

  19. Activity Modelling and Comparative Evaluation of WSN MAC Security Attacks

    DEFF Research Database (Denmark)

    Pawar, Pranav M.; Nielsen, Rasmus Hjorth; Prasad, Neeli R.

    2012-01-01

    and initiate security attacks that disturb the normal functioning of the network in a severe manner. Such attacks affect the performance of the network by increasing the energy consumption, by reducing throughput and by inducing long delays. Of all existing WSN attacks, MAC layer attacks are considered....... The second aim of the paper is to simulate these attacks on hybrid MAC mechanisms, which shows the performance degradation of aWSN under the considered attacks. The modelling and implementation of the security attacks give an actual view of the network which can be useful in further investigating secure......Applications of wireless sensor networks (WSNs) are growing tremendously in the domains of habitat, tele-health, industry monitoring, vehicular networks, home automation and agriculture. This trend is a strong motivation for malicious users to increase their focus on WSNs and to develop...

  20. Mac OS X Server Snow Leopard 雪豹

    Institute of Scientific and Technical Information of China (English)

    王炳晨

    2010-01-01

    日前,苹果公司宣布推出Mac OSX Server Snow Leopard服务器系统。这是一个真正意义的全64位操作系统,为充分发挥多核心处理器和内存的性能而设计,且完全兼容32位应用程序。

  1. LHC@home online tutorial for Mac users - recording

    CERN Document Server

    CERN. Geneva

    2016-01-01

    A step-by-step online tutorial about LHC@home for Mac users by Alexandre Racine. It contains detailed instructions on how-to-join this volunteer computing project.  There are 3 screen capture videos with the real installation process accelerated attached to the event page. This 5' video is linked from http://lhcathome.web.cern.ch/join-us Also from the CDS e-learning category.

  2. Supporting service differentiation with enhancements of the IEEE 802.11 MAC protocol: Models and analysis

    Institute of Scientific and Technical Information of China (English)

    2007-01-01

    As one of the fastest growing wireless access technologies, wireless LANs must evolve to support adequate degrees of service differentiation. Unfortunately, current WLAN standards like IEEE 802.11 Distributed Coordination Function (DCF) lack this ability. Work is in progress to define an enhanced version capable of supporting QoS for multimedia traffic at the MAC layer. In this paper, we aim at gaining insight into three mechanisms to differentiate among traffic categories, i.e., differentiating the minimum contention window size, the Inter-Frame Spacing (IFS), and the length of the packet payload according to the priority of different traffic categories. We propose an analysis model to compute the throughput and packet transmission delays. In addition, we derive approximations to obtain simpler but more meaningful relationships among different parameters. Comparisons with discrete-event simulation results show that good accuracy of performance evaluation can be achieved by using the proposed analysis model.

  3. On the Selection of MAC Optimised Routing Protocol for VANET

    Directory of Open Access Journals (Sweden)

    Kanu Priya

    2017-02-01

    Full Text Available In today‘s era of modernization, the concept of smart vehicles, smart cities and automated vehicles is trending day by day. VANET (Vehicular Adhoc Network has also been emerging as a potential applicant to enable these smart applications. Though VANET is very much similar to MANET (Mobile Adhoc Network but VANET has more severe challenges as compared to MANET due to hostile channel conditions and high degree of mobility. So lot of work related to MAC and Network Layer need attention from the network designers. In this paper MAC Layer has been optimised in terms of Queue Size by using QoS Parameters namely Packet Collision Rate, Packet Drop Rate, Throughput Rate and Broadcast Rate. In doing so, simulative investigations have been done to find out optimum queue size. For this purpose various routing protocols namely DSDV, AODV, ADV and GOD have been considered and optimum queue length for each of these have been obtained. Further the most efficient routing protocol has also been identified. Moreover this paper also compares the performance of most efficient Routing Protocols selected in terms of QoS parameters for different MAC Interfaces.

  4. 42 CFR 423.2140 - MAC Review of ALJ decision in a case remanded by a Federal District Court.

    Science.gov (United States)

    2010-10-01

    ... 42 Public Health 3 2010-10-01 2010-10-01 false MAC Review of ALJ decision in a case remanded by a... BENEFIT Reopening, ALJ Hearings, MAC review, and Judicial Review § 423.2140 MAC Review of ALJ decision in..., when a case is remanded by a Federal District Court for further consideration and the MAC remands the...

  5. Tool for Generation of MAC/GMC Representative Unit Cell for CMC/PMC Analysis

    Science.gov (United States)

    Murthy, Pappu L. N.; Pineda, Evan J.

    2016-01-01

    This document describes a recently developed analysis tool that enhances the resident capabilities of the Micromechanics Analysis Code with the Generalized Method of Cells (MAC/GMC) 4.0. This tool is especially useful in analyzing ceramic matrix composites (CMCs), where higher fidelity with improved accuracy of local response is needed. The tool, however, can be used for analyzing polymer matrix composites (PMCs) as well. MAC/GMC 4.0 is a composite material and laminate analysis software developed at NASA Glenn Research Center. The software package has been built around the concept of the generalized method of cells (GMC). The computer code is developed with a user friendly framework, along with a library of local inelastic, damage, and failure models. Further, application of simulated thermomechanical loading, generation of output results, and selection of architectures to represent the composite material have been automated to increase the user friendliness, as well as to make it more robust in terms of input preparation and code execution. Finally, classical lamination theory has been implemented within the software, wherein GMC is used to model the composite material response of each ply. Thus, the full range of GMC composite material capabilities is available for analysis of arbitrary laminate configurations as well. The primary focus of the current effort is to provide a graphical user interface (GUI) capability that generates a number of different user-defined repeating unit cells (RUCs). In addition, the code has provisions for generation of a MAC/GMC-compatible input text file that can be merged with any MAC/GMC input file tailored to analyze composite materials. Although the primary intention was to address the three different constituents and phases that are usually present in CMCs-namely, fibers, matrix, and interphase-it can be easily modified to address two-phase polymer matrix composite (PMC) materials where an interphase is absent. Currently, the

  6. Determination of sevoflurane minimum alveolar concentration in newborn and adult rats%新生及成年大鼠七氟醚 MAC 值的测定

    Institute of Scientific and Technical Information of China (English)

    黄艳; 杨小霖; 黄三

    2016-01-01

    Objective To measure and compare sevoflurane minimum alveolar concentration (MAC)in newborn and adult rats.Methods The rats were divided into newborn rat (6-8 days) group (25 cases)and adult rat (8-10 weeks)group (25 cases).All rats were settled in the self-made device for anesthesia with inhaled sevoflurane,and the tails of rats were exposed out of the device. Sevoflurane was given via an anesthesia machine.Up-and-down method and clamping tail stimulus were applied to measure the MAC values of sevoflurane in the two groups.1.5% of sevoflurane was set as the initial concentration,and± 0.2% as adjustable gradient.A positive or negative response was judged by clamping tail stimulus in a 20 minutes interval.The mean MAC value of all rats in each group was defined as the MAC value.Results The MAC value of newborn rats was (2.58 ± 0.1 1)%,and the MAC value of adult rats was (2.32 ±0.13)%.A significant difference was found between the two groups (P <0.01).Conclusion The MAC value of newborn rats was much higher than that of adult rats.Newborn rats need a higher concentration of sevoflurane at the same depth of anesthesia when compared with adult rats.%目的:测定并比较新生及成年大鼠七氟醚的最低肺泡有效浓度(MAC)。方法选择健康新生及成年 SD 大鼠各25只。两组大鼠分别放入自制大鼠麻醉装置,露出其尾部。七氟醚气体经麻醉机挥发罐输入麻醉装置。采用序贯法及夹尾刺激测定七氟醚 MAC。七氟醚初始测定浓度为1.5%,调节梯度为±0.2%。每间隔20 min 重复夹尾试验判断麻醉效果并抽取气体样本3~5 ml 测定七氟醚浓度。如此反复,使每只大鼠均获得一个阳性与阴性反应的交叉点。组内每只大鼠 MAC值的均值即为该组大鼠的 MAC 值。结果新生大鼠 MAC 值为(2.58±0.11)%,明显高于成年大鼠的 MAC 值(2.32±0.13)%(P <0.01)。结论新生大鼠的七氟醚 MAC 值明显高于成年大鼠,达到同一麻醉深度时

  7. Definition of the jianfengling species group of the ground beetle genus Orthogonius MacLeay (Coleoptera, Carabidae, Orthogoniini)

    Science.gov (United States)

    Tian, Mingyi; Deuve, Thierry

    2016-01-01

    Abstract The jianfengling species group of the termitophilous carabid genus Orthogonius MacLeay, 1825 is defined and reviewed. This species group ranges from southern China, crossing Indochina and Myanmar to eastern India. To date, the jianfengling species group is composed of ten species, including six new species which are hereinafter described and illustrated: Orthogonius wrasei sp. n. (Myanmar), Orthogonius bellus sp. n. and Orthogonius limbourgi sp. n. (Vietnam), Orthogonius politior sp. n., Orthogonius aberlenci sp. n. (Laos) and Orthogonius meghalayaensis sp. n. (India). Habitus, elytral apices and male genitalia of all species are illustrated. A key to species and a distribution map of jianfengling species group are provided. PMID:27667943

  8. Leukocyte integrin Mac-1 regulates thrombosis via interaction with platelet GPIbα.

    Science.gov (United States)

    Wang, Yunmei; Gao, Huiyun; Shi, Can; Erhardt, Paul W; Pavlovsky, Alexander; A Soloviev, Dmitry; Bledzka, Kamila; Ustinov, Valentin; Zhu, Liang; Qin, Jun; Munday, Adam D; Lopez, Jose; Plow, Edward; Simon, Daniel I

    2017-05-30

    Inflammation and thrombosis occur together in many diseases. The leukocyte integrin Mac-1 (also known as integrin αMβ2, or CD11b/CD18) is crucial for leukocyte recruitment to the endothelium, and Mac-1 engagement of platelet GPIbα is required for injury responses in diverse disease models. However, the role of Mac-1 in thrombosis is undefined. Here we report that mice with Mac-1 deficiency (Mac-1(-/-)) or mutation of the Mac-1-binding site for GPIbα have delayed thrombosis after carotid artery and cremaster microvascular injury without affecting parameters of haemostasis. Adoptive wild-type leukocyte transfer rescues the thrombosis defect in Mac-1(-/-) mice, and Mac-1-dependent regulation of the transcription factor Foxp1 contributes to thrombosis as evidenced by delayed thrombosis in mice with monocyte-/macrophage-specific overexpression of Foxp1. Antibody and small-molecule targeting of Mac-1:GPIbα inhibits thrombosis. Our data identify a new pathway of thrombosis involving leukocyte Mac-1 and platelet GPIbα, and suggest that targeting this interaction has anti-thrombotic therapeutic potential with reduced bleeding risk.

  9. Characteristics of Mycobacterium avium complex (MAC) pulmonary disease in previously treated lung cancer patients.

    Science.gov (United States)

    Meier, Erin; Pennington, Kelly; Gallo de Moraes, Alice; Escalante, Patricio

    2017-01-01

    Mycobacterium avium complex (MAC) is responsible for a large portion of non-tuberculous mycobacterial (NTM) infections worldwide. Host factors such as active malignancy, immunosuppression, chronic obstructive pulmonary disease (COPD) and bronchiectasis increase the risk of MAC infection. However, the relationship between previously treated lung cancer with subsequent development of MAC pulmonary disease and treatment outcomes have not been previously studied. We retrospectively identified all patients with lung cancer and MAC pulmonary disease documented in medical records at Mayo Clinic between January 2005 and October 2016. Patients who were diagnosed with MAC pulmonary disease before or at the time of lung cancer diagnosis were excluded. Patients meeting all inclusion criteria underwent chart review for prior oncologic treatments, clinical characteristics, and MAC treatment response. We identified 13 patients with MAC pulmonary disease and prior lung cancer, including 4 men and 9 women. Eight patients had structural lung disease that can predispose to MAC pulmonary disease, including bronchiectasis (23.0%) and COPD (46.2%). Four (30.8%) had no apparent immunosuppression or other risk factor(s) for MAC pulmonary disease. Primary pulmonary malignancies included pulmonary carcinoid, adenocarcinoma, and squamous cell carcinoma. Ten (76.9%) patients were started on antimicrobial treatment for MAC, and 8 (61.5%) patients completed MAC treatment with 6 (46.1%) patients achieving symptomatic improvement. MAC pulmonary disease in previously treated lung cancer can occur without apparent risk factors for this NTM infection. Symptomatic improvement with MAC antimicrobial therapy appears to be lower than expected but comorbidities might influence outcomes in this patient population.

  10. Intra Cluster Light properties in the CLASH-VLT cluster MACS J1206.2-0847

    CERN Document Server

    Presotto, V; Nonino, M; Mercurio, A; Grillo, C; Rosati, P; Biviano, A; Annunziatella, M; Balestra, I; Cui, W; Sartoris, B; Lemze, D; Ascaso, B; Moustakas, J; Ford, H; Fritz, A; Czoske, O; Ettori, S; Kuchner, U; Lombardi, M; Maier, C; Medezinski, E; Molino, A; Scodeggio, M; Strazzullo, V; Tozzi, P; Ziegler, B; Bartelmann, M; Benitez, N; Bradley, L; Brescia, M; Broadhurst, T; Coe, D; Donahue, M; Gobat, R; Graves, G; Kelson, D; Koekemoer, A; Melchior, P; Meneghetti, M; Merten, J; Moustakas, L; Munari, E; Postman, M; Regős, E; Seitz, S; Umetsu, K; Zheng, W; Zitrin, A

    2014-01-01

    We aim at constraining the assembly history of clusters by studying the intra cluster light (ICL) properties, estimating its contribution to the fraction of baryons in stars, f*, and understanding possible systematics/bias using different ICL detection techniques. We developed an automated method, GALtoICL, based on the software GALAPAGOS to obtain a refined version of typical BCG+ICL maps. We applied this method to our test case MACS J1206.2-0847, a massive cluster located at z=0.44, that is part of the CLASH sample. Using deep multi-band SUBARU images, we extracted the surface brightness (SB) profile of the BCG+ICL and we studied the ICL morphology, color, and contribution to f* out to R500. We repeated the same analysis using a different definition of the ICL, SBlimit method, i.e. a SB cut-off level, to compare the results. The most peculiar feature of the ICL in MACS1206 is its asymmetric radial distribution, with an excess in the SE direction and extending towards the 2nd brightest cluster galaxy which i...

  11. A MAC based excitation frequency increasing method for structural topology optimization under harmonic excitations

    Directory of Open Access Journals (Sweden)

    Liu Tao

    2017-01-01

    Full Text Available This work is focused on the topology optimization of structures that are subjected to harmonic force excitation with prescribed frequency and amplitude. As an important objective of such a design problem, the natural resonance frequency of the structure is driven far away from the prescribed excitation frequency for the purpose of avoiding resonance and reducing the vibration level. Therefore when the excitation frequency is higher than the natural resonance frequency of the structure, the natural resonance frequency will decrease, then the optimum topology configuration will be distorted with large amount of gray elements. A MAC (Modal Assurance Criteria based excitation frequency increasing method is proposed to obtain a desired configuration. MAC is adopted here to track the natural resonance frequency which can provide the baseline reference for the current excitation frequency during the optimum iterative procedure. Then the excitation frequency increases progressively up to its originally prescribed value. By means of numerical examples, the proposed formulation can generate effective topology configurations which can avoid resonance.

  12. Staged optimization algorithms based MAC dynamic bandwidth allocation for OFDMA-PON

    Science.gov (United States)

    Liu, Yafan; Qian, Chen; Cao, Bingyao; Dun, Han; Shi, Yan; Zou, Junni; Lin, Rujian; Wang, Min

    2016-06-01

    Orthogonal frequency division multiple access passive optical network (OFDMA-PON) has being considered as a promising solution for next generation PONs due to its high spectral efficiency and flexible bandwidth allocation scheme. In order to take full advantage of these merits of OFDMA-PON, a high-efficiency medium access control (MAC) dynamic bandwidth allocation (DBA) scheme is needed. In this paper, we propose two DBA algorithms which can act on two different stages of a resource allocation process. To achieve higher bandwidth utilization and ensure the equity of ONUs, we propose a DBA algorithm based on frame structure for the stage of physical layer mapping. Targeting the global quality of service (QoS) of OFDMA-PON, we propose a full-range DBA algorithm with service level agreement (SLA) and class of service (CoS) for the stage of bandwidth allocation arbitration. The performance of the proposed MAC DBA scheme containing these two algorithms is evaluated using numerical simulations. Simulations of a 15 Gbps network with 1024 sub-carriers and 32 ONUs demonstrate the maximum network throughput of 14.87 Gbps and the maximum packet delay of 1.45 ms for the highest priority CoS under high load condition.

  13. C-MAC videolaryngoscope compared with direct laryngoscopy for rapid sequence intubation in an emergency department: A randomised clinical trial.

    Science.gov (United States)

    Sulser, Simon; Ubmann, Dirk; Schlaepfer, Martin; Brueesch, Martin; Goliasch, Georg; Seifert, Burkhardt; Spahn, Donat R; Ruetzler, Kurt

    2016-12-01

    patients were enrolled, but three patients had to be excluded from the analysis, resulting in 74 patients in the C-MAC videolaryngoscopy group and 73 patients in the direct laryngoscopy group. Tracheal intubation was achieved successfully at the first attempt in 73 of 74 patients in the C-MAC group and all patients in the direct laryngoscopy group (P = 1.0). Time to intubation was similar (32 ± 11 vs. 31 ± 9 s, P = 0.51) in both groups. Visualisation of the vocal cords, represented as the Cormack and Lehane score, was significantly better using the C-MAC videolaryngoscope (P MAC videolaryngoscope compared with direct laryngoscopy. Better visualisation did not improve first-attempt success rate, which in turn was probably based on the high level of experience of the participating anaesthesia consultants. Clinicaltrials.gov identifier NCT02297113.

  14. Defining systems expertise: effective simulation at the organizational level--implications for patient safety, disaster surge capacity, and facilitating the systems interface.

    Science.gov (United States)

    Kaji, Amy H; Bair, Aaron; Okuda, Yasuharu; Kobayashi, Leo; Khare, Rahul; Vozenilek, John

    2008-11-01

    The Institute of Medicine's report "To Err is Human" identified simulation as a means to enhance safety in the medical field, just as flight simulation is used to improve the aviation industry. Yet, while there is evidence that simulation may improve task performance, there is little evidence that simulation actually improves patient outcome. Similarly, simulation is currently used to model teamwork-communication skills for disaster management and critical events, but little research or evidence exists to show that simulation improves disaster response or facilitates intersystem or interagency communication. Simulation ranges from the use of standardized patient encounters to robot-mannequins to computerized virtual environments. As such, the field of simulation covers a broad range of interactions, from patient-physician encounters to that of the interfaces between larger systems and agencies. As part of the 2008 Academic Emergency Medicine Consensus Conference on the Science of Simulation, our group sought to identify key research questions that would inform our understanding of simulation's impact at the organizational level. We combined an online discussion group of emergency physicians, an extensive review of the literature, and a "public hearing" of the questions at the Consensus Conference to establish recommendations. The authors identified the following six research questions: 1) what objective methods and measures may be used to demonstrate that simulator training actually improves patient safety? 2) How can we effectively feedback information from error reporting systems into simulation training and thereby improve patient safety? 3) How can simulator training be used to identify disaster risk and improve disaster response? 4) How can simulation be used to assess and enhance hospital surge capacity? 5) What methods and outcome measures should be used to demonstrate that teamwork simulation training improves disaster response? and 6) How can the interface

  15. THE INFLUENCE OF MAC BUFFER ON THE CONTENTION-BASED ACCESS SCHEME WITH BURSTING OPTION FOR IEEE 802.11E WIRELESS NETWORKS

    Directory of Open Access Journals (Sweden)

    S. SELVAKENNEDY

    2006-12-01

    Full Text Available Wireless LANs are increasingly being used for inelastic applications. Currently, there is little support for quality of service in the IEEE 802.11 MAC protocol, and IEEE task group E has defined the 802.11e MAC extension. Enhanced distributed channel access (EDCA is a contention-based scheme of the 802.11e standard. To allow a station to transmit more than one frame from a single contention, an optional feature known as controlled frame-bursting (CFB is introduced in the standard. In this paper, we initially performed an average analysis to determine a suitable burst duration limit. Then, a detailed evaluation and comparison of the EDCA protocol with the CFB option is carried out through simulation to quantify its performance gain. The impact of the MAC transmit buffer size is also incorporated. Accordingly, we have proposed a suitable approach to guide the configuration of the burst duration limit. It is demonstrated that an optimized CFB configuration allows the MAC protocol to achieve 30% more capacity than the basic EDCA scheme.

  16. Design of High Speed Architecture of Parallel MAC Based On Radix-2 MBA

    Directory of Open Access Journals (Sweden)

    Syed Anwar Ahmed,

    2014-05-01

    Full Text Available The multiplier and multiplier-and-accumulator (MAC are the essential elements of the digital signal processing such as filtering, convolution, transformations and Inner products. Parallel MAC is frequently used in digital signal processing and video/graphics applications. Fast multipliers are essential parts of digital signal processing systems. The speed of multiply operation is of great importance in digital signal processing as well as in the general purpose processors today, especially since the media processing took off. The MAC provides high speed multiplication and multiplication with accumulative addition. This paper presents a combined process of multiplication and accumulation based on radix-4 & radix-8 booth encodings. In this Paper, we investigate the method of implementing the Parallel MAC with the smallest possible delay. Enhancing the speed of operation of the parallel MAC is a major design issue. This has been achieved by developing a CLA adder for parallel MAC.

  17. TMAC: Timestamp-Ordered MAC Protocol for Wireless Mesh Networks

    KAUST Repository

    Nawab, Faisal

    2011-05-01

    Wireless Mesh Networks (WMNs) have emerged to meet a need for a self-organized and self-configured multi-hop wireless network infrastructure. Low cost infrastructure and ease of deployment have made WMNs an attractive technology for last mile access. However, 802.11 based WMNs are subject to serious fairness issues. With backlogged TCP traffic, nodes which are two or more hops away from the gateway are subject to starvation, while the one-hop away node saturates the channel with its own local traffic. We study the interactions of TCP and IEEE 802.11 MAC in WMNs to aid us in understanding and overcoming the unfairness problem. We propose a Markov chain to capture the behavior of TCP sessions, particularly the impact on network throughput performance due to the effect of queue utilization and packet relaying. A closed form solution is derived to numerically derive the throughput. Based on the developed model, we propose a distributed MAC protocol called Timestamp-ordered MAC (TMAC), aiming to alleviate the unfairness problem in WMNs via a manipulative per-node scheduling mechanism which takes advantage of the age of each packet as a priority metric. Simulation is conducted to validate our model and to illustrate the fairness characteristics of TMAC. Our results show that TMAC achieves excellent resource allocation fairness while maintaining above 90% of maximum link capacity in parking lot and large grid topologies. Our work illuminates the factors affecting TCP fairness in WMNs. Our theoretical and empirical findings can be used in future research to develop more fairness-aware protocols for WMNs.

  18. Tournament MAC with Constant Size Congestion Window for WLAN

    CERN Document Server

    Galtier, Jerome

    2007-01-01

    In the context of radio distributed networks, we present a generalized approach for the Medium Access Control (MAC) with fixed congestion window. Our protocol is quite simple to analyze and can be used in a lot of different situations. We give mathematical evidence showing that our performance is tight, in the sense that no protocol with fixed congestion window can do better. We also place ourselves in the WiFi/WiMAX framework, and show experimental results enlightening collision reduction of 14% to 21% compared to the best known other methods. We show channel capacity improvement, and fairness considerations.

  19. Dual Description of Supergravity MacDowell-Mansouri Theory

    CERN Document Server

    García-Compéan, H; Obregón, O; Ramírez, C

    1999-01-01

    In the context of field theory two elements seem to be necessary to search for strong-weak coupling duality. First, one needs a gauge theory and second, it should be supersymmetric. For gravitation these two elements are present in MacDowell-Mansouri supergravity. The search for an "effective duality" in this theory presents technical and conceptual problems that we discuss. Nevertheless, by means of a field theoretical approach, which in the abelian case coincides with $S$-duality, we exhibit a dual theory for supergravity, with inverted couplings. This results in a supersymmetric non-linear sigma model of the Freedman-Townsend type.

  20. Mac configuration management at the Los Alamos National Laboratory

    Energy Technology Data Exchange (ETDEWEB)

    Marcus, Allan B [Los Alamos National Laboratory

    2010-01-01

    The Los Alamos National Laboratory (LANL) had a need for central configuration management of non-Windows computers. LANL has three to five thousand Macs and an equal number of Linux based systems. The primary goal was to be able to inventory all non-windows systems and patch Mc OS X systems. LANL examined a number of commercial and open source solutions and ultimately selected Puppet. This paper will discuss why we chose Puppet, how we implemented it, and some lessons we learned along the way.

  1. Proximate analysis of coal by Leco MAC-400

    Energy Technology Data Exchange (ETDEWEB)

    Wilson, S.T. (British Steel Corporation, London (UK). Ravenscraig Works)

    1988-01-01

    Discussion is presented of the use of the Leco Mac-400 Proximate Analyser at the Ravenscraig Steel Works, UK. It is used for the analysis of in-plant coals and the determination of ash in coke. The instrument does not meet the British Standard requirement for repeatability, so is not used for 'value in use' coal analysis. It has recently been overhauled, however, and will be re-evaluated to see if the overhaul has brought an improvement in performance. 6 figs., 7 tabs.

  2. Intelligent Cooperative MAC Protocol for Balancing Energy Consumption

    Science.gov (United States)

    Wu, S.; Liu, K.; Huang, B.; Liu, F.

    To extend the lifetime of wireless sensor networks, we proposed an intelligent balanced energy consumption cooperative MAC protocol (IBEC-CMAC) based on the multi-node cooperative transmission model. The protocol has priority to access high-quality channels for reducing energy consumption of each transmission. It can also balance the energy consumption among cooperative nodes by using high residual energy nodes instead of excessively consuming some node's energy. Simulation results show that IBEC-CMAC can obtain longer network lifetime and higher energy utilization than direct transmission.

  3. Minimum alveolar concentration (MAC) for sevoflurane and xenon at normothermia and hypothermia in newborn pigs.

    Science.gov (United States)

    Liu, X; Dingley, J; Elstad, M; Scull-Brown, E; Steen, P A; Thoresen, M

    2013-05-01

    Neuroprotection from therapeutic hypothermia increases when combined with the anaesthetic gas xenon in animal studies. A clinical feasibility study of the combined treatment has been successfully undertaken in asphyxiated human term newborns. It is unknown whether xenon alone would be sufficient for sedation during hypothermia eliminating or reducing the need for other sedative or analgesic infusions in ventilated sick infants. Minimum alveolar concentration (MAC) of xenon is unknown in any neonatal species. Eight newborn pigs were anaesthetised with sevoflurane alone and then sevoflurane plus xenon at two temperatures. Pigs were randomised to start at either 38.5°C or 33.5°C. MAC for sevoflurane was determined using the claw clamp technique at the preset body temperature. For xenon MAC determination, a background of 0.5 MAC sevoflurane was used, and 60% xenon added to the gas mixture. The relationship between sevoflurane and xenon MAC is assumed to be additive. Xenon concentrations were changed in 5% steps until a positive clamp reaction was noted. Pigs' temperature was changed to the second target, and two MAC determinations for sevoflurane and 0.5 MAC sevoflurane plus xenon were repeated. MAC for sevoflurane was 4.1% [95% confidence interval (CI): 3.65-4.50] at 38.5°C and 3.05% (CI: 2.63-3.48) at 33.5°C, a significant reduction. MAC for xenon was 120% at 38.5°C and 116% at 33.5°C, not different. In newborn swine sevoflurane, MAC was temperature dependent, while xenon MAC was independent of temperature. There was large individual variability in xenon MAC, from 60% to 120%. © 2013 The Acta Anaesthesiologica Scandinavica Foundation.

  4. MQ-MAC: A Multi-Constrained QoS-Aware Duty Cycle MAC for Heterogeneous Traffic in Wireless Sensor Networks

    Science.gov (United States)

    Monowar, Muhammad Mostafa; Rahman, Md. Obaidur; Hong, Choong Seon; Lee, Sungwon

    2010-01-01

    Energy conservation is one of the striking research issues now-a-days for power constrained wireless sensor networks (WSNs) and hence, several duty-cycle based MAC protocols have been devised for WSNs in the last few years. However, assimilation of diverse applications with different QoS requirements (i.e., delay and reliability) within the same network also necessitates in devising a generic duty-cycle based MAC protocol that can achieve both the delay and reliability guarantee, termed as multi-constrained QoS, while preserving the energy efficiency. To address this, in this paper, we propose a Multi-constrained QoS-aware duty-cycle MAC for heterogeneous traffic in WSNs (MQ-MAC). MQ-MAC classifies the traffic based on their multi-constrained QoS demands. Through extensive simulation using ns-2 we evaluate the performance of MQ-MAC. MQ-MAC provides the desired delay and reliability guarantee according to the nature of the traffic classes as well as achieves energy efficiency. PMID:22163439

  5. MQ-MAC: a multi-constrained QoS-aware duty cycle MAC for heterogeneous traffic in wireless sensor networks.

    Science.gov (United States)

    Monowar, Muhammad Mostafa; Rahman, Md Obaidur; Hong, Choong Seon; Lee, Sungwon

    2010-01-01

    Energy conservation is one of the striking research issues now-a-days for power constrained wireless sensor networks (WSNs) and hence, several duty-cycle based MAC protocols have been devised for WSNs in the last few years. However, assimilation of diverse applications with different QoS requirements (i.e., delay and reliability) within the same network also necessitates in devising a generic duty-cycle based MAC protocol that can achieve both the delay and reliability guarantee, termed as multi-constrained QoS, while preserving the energy efficiency. To address this, in this paper, we propose a Multi-constrained QoS-aware duty-cycle MAC for heterogeneous traffic in WSNs (MQ-MAC). MQ-MAC classifies the traffic based on their multi-constrained QoS demands. Through extensive simulation using ns-2 we evaluate the performance of MQ-MAC. MQ-MAC provides the desired delay and reliability guarantee according to the nature of the traffic classes as well as achieves energy efficiency.

  6. MQ-MAC: A Multi-Constrained QoS-Aware Duty Cycle MAC for Heterogeneous Traffic in Wireless Sensor Networks

    Directory of Open Access Journals (Sweden)

    Sungwon Lee

    2010-11-01

    Full Text Available Energy conservation is one of the striking research issues now-a-days for power constrained wireless sensor networks (WSNs and hence, several duty-cycle based MAC protocols have been devised for WSNs in the last few years. However, assimilation of diverse applications with different QoS requirements (i.e., delay and reliability within the same network also necessitates in devising a generic duty-cycle based MAC protocol that can achieve both the delay and reliability guarantee, termed as multi-constrained QoS, while preserving the energy efficiency. To address this, in this paper, we propose a Multi-constrained QoS-aware duty-cycle MAC for heterogeneous traffic in WSNs (MQ-MAC. MQ-MAC classifies the traffic based on their multi-constrained QoS demands. Through extensive simulation using ns-2 we evaluate the performance of MQ-MAC. MQ-MAC provides the desired delay and reliability guarantee according to the nature of the traffic classes as well as achieves energy efficiency.

  7. Mycobacterium colombiense sp. nov., a novel member of the Mycobacterium avium complex and description of MAC-X as a new ITS genetic variant.

    Science.gov (United States)

    Murcia, Martha I; Tortoli, Enrico; Menendez, M Carmen; Palenque, Elia; Garcia, Maria J

    2006-09-01

    Forty-five mycobacterial strains isolated from 23 Colombian HIV-positive patients were identified as members of the Mycobacterium avium complex (MAC) and were characterized using different molecular approaches. Seven of the isolates showed characteristic features that allowed them to be differentiated from other members of the complex. The isolates had a novel 16S-23S rRNA internal transcribed spacer (ITS 1) gene sequence which is described as a new sequevar, MAC-X. All of the seven novel isolates gave a positive result with the MAC-specific AccuProbe (Gen-Probe), but tested negative for Mycobacterium avium and Mycobacterium intracellulare species-specific probes (64 and 100 % of the isolates, respectively). The novel isolates could be differentiated phenotypically from other members of the MAC on the basis of the production of urease and by a consistent mycolic acid pattern. The novel isolates shared some characteristics with M. avium, such as the avium variant I (av-I) pattern of the hsp65 gene as determined by PCR restriction analysis and a positive PCR result for the mig (macrophage-induced) gene. However, the novel isolates showed a unique 16S rRNA gene sequence. DNA-DNA relatedness values, from 24 to 44 %, confirmed the distinction of the novel isolates from other members of the MAC at the genetic level and their status as members of a separate species. The novel isolates are proposed as representatives of a novel species, Mycobacterium colombiense sp. nov., that is closely related to M. avium within the MAC. The type strain is 10B(T) (=CIP 108962(T)=CECT 3035(T)).

  8. TM6SF2 and MAC30, new enzyme homologues in sterol metabolism and common metabolic disease.

    Directory of Open Access Journals (Sweden)

    Luis eSanchez-Pulido

    2014-12-01

    Full Text Available Carriers of the Glu167Lys coding variant in the TM6SF2 gene have recently been identified as being more susceptible to non-alcoholic fatty liver disease (NAFLD, yet exhibit lower levels of circulating lipids and hence are protected against cardiovascular disease. Despite the physiological importance of these observations, the molecular function of TM6SF2 remains unknown, and no sequence similarity with functionally characterised proteins has been identified. In order to trace its evolutionary history and to identify functional domains, we embarked on a computational protein sequence analysis of TM6SF2. We identified a new domain, the EXPERA domain, which is conserved among TM6SF, MAC30/TMEM97 and EBP (D8,D7 sterol isomerase protein families. EBP mutations are the cause of chondrodysplasia punctata 2 X-linked dominant (CDPX2, also known as Conradi-Hünermann-Happle syndrome, a defective cholesterol biosynthesis disorder. Our analysis of evolutionary conservation among EXPERA domain-containing families and the previously suggested catalytic mechanism for the EBP enzyme, indicate that TM6SF and MAC30/TMEM97 families are both highly likely to possess, as for the EBP family, catalytic activity as sterol isomerases. This unexpected prediction of enzymatic functions for TM6SF and MAC30/TMEM97 is important because it now permits detailed experiments to investigate the function of these key proteins in various human pathologies, from cardiovascular disease to cancer.

  9. Power-Controlled MAC Protocols with Dynamic Neighbor Prediction for Ad hoc Networks

    Institute of Scientific and Technical Information of China (English)

    LI Meng; ZHANG Lin; XIAO Yong-kang; SHAN Xiu-ming

    2004-01-01

    Energy and bandwidth are the scarce resources in ad hoc networks because most of the mobile nodes are battery-supplied and share the exclusive wireless medium. Integrating the power control into MAC protocol is a promising technique to fully exploit these precious resources of ad hoc wireless networks. In this paper, a new intelligent power-controlled Medium Access Control (MAC) (iMAC) protocol with dynamic neighbor prediction is proposed. Through the elaborate design of the distributed transmit-receive strategy of mobile nodes, iMAC greatly outperforms the prevailing IEEE 802.11 MAC protocols in not only energy conservation but also network throughput. Using the Dynamic Neighbor Prediction (DNP), iMAC performs well in mobile scenes. To the best of our knowledge, iMAC is the first protocol that considers the performance deterioration of power-controlled MAC protocols in mobile scenes and then proposes a solution. Simulation results indicate that DNP is important and necessary for power-controlled MAC protocols in mobile ad hoc networks.

  10. PA-MAC:A Passive Asynchronous MAC Protocol for Low Duty-Cycled Wireless Sensor Networks%PA-MAC:一种被动的异步低占空比无线传感器网络MAC协议

    Institute of Scientific and Technical Information of China (English)

    唐震洲; 施晓秋; 金可仲

    2011-01-01

    空闲侦听是无线传感器网络能耗的主要原因之一,而占空比机制是减少空闲侦听能量损耗最主要的方法之一.提出了一种新的无线传感器网络异步MAC协议,称为PA-MAC(Passive Asynchronous MAC),即被动异步MAC.PA-MAC通过采用接收方发起数据传输机制、异步占空比机制以及节点唤醒时间估计机制,降低了节点的工作占空比,提高了网络的能量有效性.在NS2网络仿真平台上对PA-MAC的性能进行了评估.仿真结果表明,在保持网络性能的前提下,PA-MAC能够进一步降低节点工作的占空比,进而减少节点的能耗.%The problem of idle listening is one of the most concerned issues in wireless sensor networks, and the duty cycling mechanism is widely used to reduce energy consumption. We present a new asynchronous MAC protocol, called Passive-Asynchronous MAC (PA-MAC). PA-MAC uses receiver-initiated data transmission scheme, asynchronous duty cycling mechanism and awakening time estimation scheme to achieve low duty cycle and high energy efficiency. Simulations have been done to evaluate the performance of the proposed new protocol, by which we can find out that,on the premise of keeping the network performance,PA-MAC can further reduce the nodes' duty cycle ,thereby reduce the energy consumption.

  11. The influence of paleogeography in epicontinental seas: A case study based on Middle Devonian strata from the MacKenzie Basin, Northwest Territories, Canada

    Science.gov (United States)

    Corlett, Hilary; Jones, Brian

    2011-08-01

    The history of Middle Devonian sea level changes are recorded in the Chinchaga Formation, Lonely Bay Formation, Horn Plateau Formation, and the Horn River Formations that originated in the MacKenzie Basin, which is located in the southern Northwest Territories, Canada. These strata record an almost consistent sea-level rise throughout the Middle Devonian with punctuated deepenings. Deposition began in the MacKenzie Basin in the Eifelian with restricted shallow water evaporites and dolomites of the Chinchaga Formation. Overlying the Chinchaga Formation are the open-marine carbonates belonging to the Lonely Bay Formation, which were overlain by the Horn Plateau Formation buildups. Pelagic shales of the Horn River Formation in the Late Givetian/Early Frasnian later covered these buildups. During the Early and Middle Devonian many continental basins in North America had limited interactions with open ocean waters. These restricted shallow-water basins were vulnerable to the effects of clastic shedding and evaporitic drawdown that commonly caused local lowstands. Several of these shallow basins, including the MacKenzie Basin, have been used to construct Devonian sea-level curves. Comparison of the Middle Devonian strata that formed in the MacKenzie Basin with well-established sea level curves shows that the Late-Givetian regression interpreted from some of those successions is not evident in the succession found in the MacKenzie Basin. This probably reflects the fact that the Mackenzie Basin was directly linked to the open ocean and was not influenced by the changes in sea level that affected many of the enclosed basins.

  12. Learning Microsoft Excel 2011 for Mac video training DVD

    CERN Document Server

    Vaccaro, Guy

    2011-01-01

    In this video tutorial for Microsoft Excel 2011 For Mac, expert author Guy Vaccaro teaches you to effectively utilize the features and functions of Excel through project based learning. You will complete various projects, and along they way learn to leverage the power of the most important features Excel 2011 has to offer the Mac user. Starting your training course with the creation of a spreadsheet to record and monitor sales data, you will learn the basics of what you can do with a spreadsheet. You will then move on to creating a Profit and Loss report, learning formulas along the way. Moving to score sheets for a sports day, you will discover conditional based formatting, lookups, and more. You then create a functional expense claim form, advancing your Excel expertise. Moving on to a sales contact management sheet, you will discover how you can manipulate text, and even create mail merges from Excel. Finally, you will utilize all your knowledge thus far to create a sales report, including charts, pivot ta...

  13. MAC Layer Resource Allocation for Wireless Body Area Networks

    Institute of Scientific and Technical Information of China (English)

    Qinghua Shen; Xuemin Sherman Shen; Tom HLuan; Jing Liu

    2014-01-01

    Wireless body area networks (WBANs) can provide low-cost, timely healthcare services and are expected to be widely used for e-healthcare in hospitals. In a hospital, space is often limited and multiple WBANs have to coexist in an area and share the same channel in order to provide healthcare services to different patients. This causes severe interference between WBANs that could significantly reduce the network throughput and increase the amount of power consumed by sensors placed on the body. There-fore, an efficient channel-resource allocation scheme in the medium access control (MAC) layer is crucial. In this paper, we devel-op a centralized MAC layer resource allocation scheme for a WBAN. We focus on mitigating the interference between WBANs and reducing the power consumed by sensors. Channel and buffer state are reported by smartphones deployed in each WBAN, and channel access allocation is performed by a central controller to maximize network throughput. Sensors have strict limitations in terms of energy consumption and computing capability and cannot provide all the necessary information for channel allocation in a timely manner. This deteriorates network performance. We exploit the temporal correlation of the body area channel in order to minimize the number of channel state reports necessary. We view the network design as a partly observable optimization prob-lem and develop a myopic policy, which we then simulate in Matlab.

  14. Anesthetic doses blocking adrenergic (stress) and cardiovascular responses to incision--MAC BAR.

    Science.gov (United States)

    Roizen, M F; Horrigan, R W; Frazer, B M

    1981-05-01

    The reaction to stress, while vital to the conscious animal, may be detrimental to the surgical patient. To assess the stress-ablating action of different anesthetics (halothane, enflurane, morphine, and spinal) and anesthetic doses, we studied the responses in plasma norepinephrine, muscle movement, pupil diameter, heart rate, and blood pressure to induction of anesthesia and incision in 170 unpremedicated healthy adults. The age-adjusted dose (mean +/- SD) of anesthesia that blocked the adrenergic response in 50 per cent of individuals who had a skin incision (MAC BAR) was 1.45 +/- 0.08 MAC for halothane, 1.60 +/- 0.13 MAC for enflurane, or 1.13 +/- 0.09 +/- mg/kg for morphine sulfate (each anesthetic was given with 60 per cent nitrous oxide). No patient with a level of spinal anesthesia that blocked the pain of incision had an adrenergic response to incision. Increasing doses of halothane and morphine were associated with less of a cardiovascular response to incision (as measured by rate-pressure product); this was not true for enflurane. No patient with an adequate level of spinal anesthesia had a cardiovascular response to skin incision. The changes in heart rate, blood pressure, rate-pressure product, and plasma norepinephrine content that occurred with induction of anesthesia tended to equalize these values between patients, regardless of anesthetic dose, and for all individual and combined anesthetics. That is, if a patient's heart rate while awake was below 63 beats/min, heart rate tended to rise 58 per cent of the difference between heart rate while awake and 63 beats/min, and vice versa. Similarly, the change in blood pressure with induction averaged 75 per cent of the difference between systolic blood pressure while awake and 88 torr. The average for the change in rate-pressure product with induction was 79 per cent of the difference between rate-pressure product while awake and 5917 torr.beats/min. It was concluded that all the anesthetics tested can

  15. Definable deduction relation

    Institute of Scientific and Technical Information of China (English)

    张玉平

    1999-01-01

    The nonmonotonic deduction relation in default reasoning is defined with fixed point style, which has the many-extension property that classical logic is not possessed of. These two kinds of deductions both have boolean definability property, that is, their extensions or deductive closures can be defined by boolean formulas. A generalized form of fixed point method is employed to define a class of deduction relations, which all have the above property. Theorems on definability and atomless boolean algebras in model theory are essential in dealing with this assertion.

  16. Mac-1 deficiency induces respiratory failure by affecting type I alveolar epithelial cells.

    Science.gov (United States)

    Wang, J; Ci, Y B; Liu, C L; Sun, H M

    2017-08-31

    As a β2 integrin family member, Mac-1 plays an important role in the inflammatory response. Inflammation and lung injury are closely associated, but the involvement of Mac-1 in the occurrence and development of such pathologies remains poorly understood. We aimed to investigate the relationship between Mac-1 deficiency and respiratory failure in Mac-1 knockout {Mac-1(-/-)} mice, using C57BL/6J mice as a control. The newborn survival rate of Mac-1(-/-) mice was calculated, and mouse lung tissue was treated with hematoxylin and eosin and subjected to immunofluorescent staining. Moreover, western blotting and immunohistochemistry were used to detect the expression of molecules specific to type I and type II alveolar epithelial cells, as well as alveolar surfactant proteins secreted by the latter. Survival of Mac-1(-/-) pups was significantly lower than that of newborn C57BL/6J mice. In a float test, lung tissues from C57BL/6J mice were buoyant, whereas those of Mac-1(-/-) mice were not. Compared with C57BL/6J mice, expression of proSP-C {specific to type II alveolar epithelial cells} and alveolar surfactant proteins in Mac-1(-/-) mice was not significantly different, implying that type II cell function was unaltered. However, western blotting revealed expression of T1α, Aqp5, and Snx5 {type I alveolar epithelial cell markers} in Mac-1(-/-) mice to be significantly decreased {P Mac-1 may play an important role in respiratory failure. Its absence leads to this condition not by influencing type II alveolar epithelial cells or their secreted surfactant proteins, but rather by reducing type I alveolar cell numbers.

  17. A Routing Priority Scheduling Algorithm for MAC Layer in Wireless Sensor Networks

    Directory of Open Access Journals (Sweden)

    Liyong Bao

    2011-03-01

    Full Text Available Based on the ideas of conflict-free transmission, priority to guarantee transmission quality for communication between the different clusters , this article proposes a scheduling Algorithm fit for the MAC scheme of WSNs, which has made it possible for the polling service capable of differentiating services of the cluster head node of two priority levels. The high-priority service of the cluster head is responsible for routing between the different clusters, via exhaustive service policy, while the low-priority services of the cluster head node, for communication within the cluster through limited service policy with good fairness. The theoretical model of this scheme is established through Markov chain and probability generating function. Mathematical analysis is made on the mean queue length, the mean inquiry cyclic time and the mean delay time. It turns out that the findings from theoretical analysis correspond well with those from simulated experiments.

  18. Application of HollySys MACS DCS to PET plant%HollySys MACS DCS在PET装置中的应用

    Institute of Scientific and Technical Information of China (English)

    霍卫

    2015-01-01

    介绍了HollySys MACS DCS在PET装置中的应用,简要说明了PET装置的生产工艺和MACS系统的主要特点,介绍了该装置控制系统的软硬件构成,阐述了HollySys MACS DCS在PET装置中应用的控制方案.

  19. 78 FR 26711 - Federal Agricultural Mortgage Corporation Funding and Fiscal Affairs; Farmer Mac Liquidity...

    Science.gov (United States)

    2013-05-08

    ...; Farmer Mac Liquidity Management ACTION: Proposed rule; reopening of comment period. SUMMARY: The Farm... amend its liquidity management regulations for the Federal Agricultural Mortgage Corporation (Farmer Mac... liquidity by addressing four definitions in Sec. 652.5,\\3\\ liquidity management in Sec. 652.35, and the...

  20. Optimization and verification of the TR-MAC protocol for wireless sensor networks

    NARCIS (Netherlands)

    Morshed, Sarwar; Heijenk, Geert

    2015-01-01

    Energy-efficiency is an important requirement in the design of communication protocols for wireless sensor networks (WSN). TR-MAC is an energy-efficient medium access control (MAC) layer protocol for low power WSN that exploits transmitted-reference (TR) modulation in the physical layer. The underly

  1. Official Portrait of STS-52 Canadian Payload Specialist Steve G. MacLean

    Science.gov (United States)

    1992-01-01

    STS-52 Canadian Payload Specialist Steven G. MacLean, wearing a launch and entry suit (LES), poses with a launch and entry helmet (LEH) and Canadian flag for his Official portrait. MacLean representing the Canadian Space Agency (CSA) will fly aboard Columbia, Orbiter Vehicle (OV) 102, for the STS-52 mission.

  2. Transcriptomic microarray analysis of BoMac cells after infection with bovine foamy virus

    NARCIS (Netherlands)

    Rola-Luszczak, M.; Materniak, M.; Pluta, A.; Hulst, M.M.; Kuz'mak, J.

    2014-01-01

    Bovine foamy virus (BFV) infections are highly prevalent among cattle worldwide. However, relatively little is known about the impact of this virus on the host immune system. In our study, we focused on a bovine macrophage cell line (BoMac) and examined changes in the BoMac transcriptome after in vi

  3. Scheduled MAC in Beacon Overlay Networks for Underwater Localization and Time-Synchronization

    NARCIS (Netherlands)

    van Kleunen, W.A.P.; Meratnia, Nirvana; Havinga, Paul J.M.

    2011-01-01

    In this article we introduce a MAC protocol designed for underwater localization and time-synchronisation. The MAC protocol assumes a network of static reference nodes and allows blind nodes to be localized by listening-only to the beacon messages. Such a system is known to be very scalable. We show

  4. Simulation of 64-bit MAC Unit using Kogge Stone Adder and Ancient Indian Mathematics

    Directory of Open Access Journals (Sweden)

    Aapurva Kaul

    2016-05-01

    Full Text Available This paper describes that multiply and accumulate (MAC unit plays a very vital role in various Digital Signal Processing applications. Speed of these applications depends on the speed of these three sub units of MAC multiply unit, adder unit and accumulator unit. In this paper the delay of 64-bit MAC unit is decreased as compared to the previous MAC units. In this Kogge Stone Adder is used as adder in design Vedic Multiplier using Urdhva Tiryakbhyam sutra. The designing of MAC unit is done under VIRTEX-4 family, XC4VFX140 device, FF1517 package and -11 speed and comparison of proposed MAC unit design is done under SPARTAN- 3E family, XC3S500 device, FG320 package and -5 speed in Xilinx ISE 8.1i. The combinational path delay of the 64-bit MAC unit is 59.705ns in SPARTAN-3E family. Ancient Indian mathematics is being used for designing of multiplier unit to decrease the overall delay of the MAC unit.

  5. A concurrent access MAC protocol for cognitive radio ad hoc networks without common control channel

    Science.gov (United States)

    Timalsina, Sunil K.; Moh, Sangman; Chung, Ilyong; Kang, Moonsoo

    2013-12-01

    Cognitive radio ad hoc networks (CRAHNs) consist of autonomous nodes that operate in ad hoc mode and aim at efficient utilization of spectrum resources. Usually, the cognitive nodes in a CRAHN exploit a number of available channels, but these channels are not necessarily common to all nodes. Such a network environment poses the problem of establishing a common control channel (CCC) as there might be no channel common to all the network members at all. In designing protocols, therefore, it is highly desirable to consider the network environment with no CCC. In this article, we propose a MAC protocol called concurrent access MAC (CA-MAC) that operates in the network environment with no CCC. The two devices in a communication pair can communicate with each other even if they have only one common channel available. Therefore, the problems with CCC (such as channel saturation and denial of service attacks) can also be resolved. In CA-MAC, channel accesses are distributed over communication pairs, resulting in increased network connectivity. In addition, CA-MAC allows different communication pairs to access multiple channels concurrently. According to our performance study, CA-MAC provides higher network connectivity with shorter channel access delay compared to SYN-MAC, which is the conventional key MAC protocol for the network environment with no CCC, resulting in better network throughput.

  6. Investigation of Mycobacterium avium complex (MAC) in Australian commercial milk using qPCR.

    Science.gov (United States)

    Adhikari, Shraddha; Caro Tohme, Tanya; Whiley, Harriet

    2017-02-01

    This technical research communication describes the first study to use quantitative polymerase chain reaction (qPCR) to investigate the presence of Mycobacterium avium complex (MAC) in Australian pasteurised milk. MAC is the most common NTM responsible for human illnesses and includes M. avium subspecies paratuberculosis (MAP). MAC is a causative agent of lymphadenitis in children, with contaminated food and water considered as a likely source. As such the presence of MAC in milk would have public health significance. MAP has been linked to Crohn's disease and is also the causative agent of Johne's disease in cattle. Previous studies have detected MAP in pasteurised milk from Brazil, India, Czech Republic, USA, Argentina, UK, Iran, Ireland and the United Kingdom. This study investigated a total of 180 commercially available Australian pasteurised milk samples which were tested for MAC DNA in triplicate using PCR. All samples were negative for MAC DNA. An additional 14 milk samples were tested, incubated for 3 weeks at 37 °C to potentially increase the concentration of any viable MAC that may be present and then retested. All samples were again negative for MAC DNA. This could be due to concentrations below the limit of detection, limited sample size or could be reflective of the Australian biosecurity control protocols and surveillance of Johne's disease in ruminant animals.

  7. An update on the side channel cryptanalysis of MACs based on cryptographic hash functions

    DEFF Research Database (Denmark)

    Gauravaram, Praveen; Okeya, Katsuyuki

    2007-01-01

    into consideration. Next, we propose new hybrid NMAC/HMAC schemes for security against side channel attacks assuming that their underlying block cipher is ideal. We then show that M-NMAC, MDx-MAC and a variant of the envelope MAC scheme based on DM with an ideal block cipher are secure against DPA attacks....

  8. THE EFFECT OF TEMPERATURE ON THE GROWTH OF MYCOBACTERIUM AVIUM COMPLEX (MAC) ORGANISMS

    Science.gov (United States)

    MAC organisms are able to grow, persist, and colonize in water distribution systems and may amplify in hospital hot water systems. This study examined the response of MAC organisms (M. avium, M. intracellulare, and MX) to a range of temperatures commonly associated with drinking...

  9. Self-Admitted Pretensions of Mac Users on a Predominantly PC University Campus

    Science.gov (United States)

    Firmin, Michael W.; Wood, Whitney L. Muhlenkamp; Firmin, Ruth L.; Wood, Jordan C.

    2010-01-01

    The present qualitative research study addressed the overall research question of college students' pretention dynamics in the context of a university setting. Thirty-five Mac users were interviewed on a university campus that exclusively supports PC machines. Mac users shared four self-admitted pretensions related to using Macintosh computers.…

  10. THE EFFECT OF TEMPERATURE ON THE GROWTH OF MYCOBACTERIUM AVIUM COMPLEX (MAC) ORGANISMS

    Science.gov (United States)

    MAC organisms are able to grow, persist, and colonize in water distribution systems and may amplify in hospital hot water systems. This study examined the response of MAC organisms (M. avium, M. intracellulare, and MX) to a range of temperatures commonly associated with drinking...

  11. Self-Admitted Pretensions of Mac Users on a Predominantly PC University Campus

    Science.gov (United States)

    Firmin, Michael W.; Wood, Whitney L. Muhlenkamp; Firmin, Ruth L.; Wood, Jordan C.

    2010-01-01

    The present qualitative research study addressed the overall research question of college students' pretention dynamics in the context of a university setting. Thirty-five Mac users were interviewed on a university campus that exclusively supports PC machines. Mac users shared four self-admitted pretensions related to using Macintosh computers.…

  12. Poincaré-MacMillan Equations of Motion for a Nonlinear Nonholonomic Dynamical System

    Institute of Scientific and Technical Information of China (English)

    Amjad Hussain; Syed Tauseef Mohyud-Din; Ahmet Yildirim

    2012-01-01

    MacMillan's equations are extended to Poincaré's formalism,and MacMillan's equations for nonlinear nonholonomic systems are obtained in terms of Poincaré parameters.The equivalence of the results obtained here with other forms of equations of motion is demonstrated.An illustrative example of the theory is provided as well.

  13. Historically defined autobiographical periods

    DEFF Research Database (Denmark)

    Brown, Norman R.; Hansen, Tia G. B.; Lee, Peter J.;

    2012-01-01

    The chapter reviews a research programme that has demonstrated the existence of historically defined autobiographical periods and identified the conditions that bring them about. Data from four samples of World War II-generation adults show that historically defined autobiographical periods endure...... over time and theoretical implications are discussed, notably by introducing a new approach to autobiographical memory, Transition Theory, which assumes that autobiographical memory is organized by transitional events that can be selfinitiated or externally imposed - historically defined...

  14. On PHY and MAC Performance in Body Sensor Networks

    Directory of Open Access Journals (Sweden)

    Sana Ullah

    2009-01-01

    Full Text Available This paper presents an empirical investigation on the performance of body implant communication using radio frequency (RF technology. In body implant communication, the electrical properties of the body influence the signal propagation in several ways. We use a Perspex body model (30 cm diameter, 80 cm height and 0.5 cm thickness filled with a liquid that mimics the electrical properties of the basic body tissues. This model is used to observe the effects of body tissue on the RF communication. We observe best performance at 3cm depth inside the liquid. We further present a simulation study of several low-power MAC protocols for an on-body sensor network and discuss the derived results. Also, the traditional preamble-based TMDA protocol is extended towards a beacon-based TDMA protocol in order to avoid preamble collision and to ensure low-power communication.

  15. Self and Otherness in Norman MacCaig’s Poetry

    Directory of Open Access Journals (Sweden)

    Dominique DELMAIRE

    2004-10-01

    Full Text Available No other Scottish poet has concerned himself more thoroughly than Norman MacCaig (1910-1996 — the author of such poems as “Ego,” “Other Self,” “Other self, same self,” and many more in the same vein — with the problematic issue of the subject and his relations to both reality and to his own multiple avatars or projections. “Other self” (Collected Poems 95 is such a case in point that it deserves full quoting:       My inmost creature, Caliban perhaps,      Perhaps St Francis (at least, a s...

  16. A Distributed MAC Protocol for Cooperation in Random Access Networks

    CERN Document Server

    Böcherer, Georg

    2008-01-01

    WLAN is one of the most successful applications of wireless communications in daily life because of low cost and ease of deployment. The enabling technique for this success is the use of random access schemes for the wireless channel. Random access requires minimal coordination between the nodes, which considerably reduces the cost of the infrastructure. Recently, cooperative communication in wireless networks has been of increasing interest because it promises higher rates and reliability. An additional MAC overhead is necessary to coordinate the nodes to allow cooperation and this overhead can possibly cancel out the cooperative benefits. In this work, a completely distributed protocol is proposed that allows nodes in the network to cooperate via Two-Hop and Decode-and-Forward for transmitting their data to a common gateway node. It is shown that high throughput gains are obtained in terms of the individual throughput that can be guaranteed to any node in the network. These results are validated by Monte Ca...

  17. Analysis and improvement of the MAC shaping mechanism in RPR

    Science.gov (United States)

    Li, Jing; Xu, Zhanqi; Yu, Shaohua

    2005-11-01

    Resilient Packet Ring (RPR) specified by IEEE 802.17 is a new standard for Metropolitan Area Networks (MANs). One of RPR's characteristics is that it can support three priorities traffic in a single datapath, i.e., class A, class B and class C, ranging from high priority to low priority, respectively. Different entities such as shaping, scheduling, fairness, topology and protection coordinate to guarantee the Quality of Service (QoS) for different services. Various pieces of the datapath in RPR are tied together through logical queues, thus we investigate the datapath from the view of logical queues in this paper. With a detailed analysis of the MAC shaping mechanism in RPR, we propose some improvement to achieve better transport performance for RPR's three priorities traffic. Simulation results show that our improvement is efficient.

  18. Marielle Macé, Le genre littéraire

    OpenAIRE

    2012-01-01

    Pour des termes génériques associés à une longue tradition et plusieurs écoles de pensée, la collection Corpus s’engage à présenter un panorama de définitions. Tel a été le cas, entre autres notions, pour celles d’auteur, de lecteur… L’ouvrage de Marielle Macé traite lui aussi d’une notion clé qui est au cœur d’une histoire plus que millénaire de la réflexion littéraire, mais aussi philosophique, voire linguistique et rhétorique, exposée aux vagues successives de remise en cause de la moderni...

  19. MacBurn's cylinder test problem

    Energy Technology Data Exchange (ETDEWEB)

    Shestakov, Aleksei I. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States)

    2016-02-29

    This note describes test problem for MacBurn which illustrates its performance. The source is centered inside a cylinder with axial-extent-to-radius ratio s.t. each end receives 1/4 of the thermal energy. The source (fireball) is modeled as either a point or as disk of finite radius, as described by Marrs et al. For the latter, the disk is divided into 13 equal area segments, each approximated as a point source and models a partially occluded fireball. If the source is modeled as a single point, one obtains very nearly the expected deposition, e.g., 1/4 of the flux on each end and energy is conserved. If the source is modeled as a disk, both conservation and energy fraction degrade. However, errors decrease if the source radius to domain size ratio decreases. Modeling the source as a disk increases run-times.

  20. Sabine MacCormack, On the Wings of Time. Rome,

    OpenAIRE

    Rey, Sarah

    2011-01-01

    Que vient faire une antiquisante sur les hauteurs andines ? Sabine MacCormack, spécialiste de l’art romain, n’a pas à se justifier. Dans cette étude, l’abondante littérature qu’elle offre au lecteur suffit à prouver l’intérêt de sa démarche qui consiste à quêter les formes, les mots et les images de l’Antiquité apposés sur l’espace inca au moment de sa découverte. L’historienne donne une suite à son étude de 1991, Religion in the Andes  : Vision and Imagination in Early Colonial Peru. Pour re...

  1. MACS low-background doubly focusing neutron monochromator

    CERN Document Server

    Smee, S A; Scharfstein, G A; Qiu, Y; Brand, P C; Anand, D K; Broholm, C L

    2002-01-01

    A novel doubly focusing neutron monochromator has been developed as part of the Multi-Analyzer Crystal Spectrometer (MACS) at the NIST Center for Neutron Research. The instrument utilizes a unique vertical focusing element that enables active vertical and horizontal focusing with a large, 357-crystal (1428 cm sup 2), array. The design significantly reduces the amount of structural material in the beam path as compared to similar instruments. Optical measurements verify the excellent focal performance of the device. Analytical and Monte Carlo simulations predict that, when mounted at the NIST cold-neutron source, the device should produce a monochromatic beam (DELTA E=0.2 meV) with flux phi>10 sup 8 n/cm sup 2 s. (orig.)

  2. Antimoulting Activity of Eremanthus erythropappus (DC. MacLeisch

    Directory of Open Access Journals (Sweden)

    Danielle Barbosa

    2012-06-01

    Resumo. Os extratos e metabólitos secundários de plantas podem agir como agentes tóxicos e inibidores do da alimentação e do desenvolvimento em insetos. Neste estudo foi utilizado Oncopeltus fasciatus (Dallas (Hemiptera como modelo experimental a fim de avaliar as atividades do extrato etanólico bruto e frações obtidos das flores ou caules de Eremanthus erythropappus (DC. MacLeisch (Asteraceae, na mortalidade e sobre o desenvolvimento do inseto. A fração butanólica obtida do extrato etanólico mostrou toxidade sobre as ninfas de O. fasciatus, bem como atividade de inibição do crescimento. Os resultados sugerem que a fração butanólica de E. erythropappus possui substâncias ativas sobre a fisiologia, crescimento e desenvolvimento de insetos.

  3. On PHY and MAC Performance in Body Sensor Networks

    Directory of Open Access Journals (Sweden)

    Higgins Henry

    2009-01-01

    Full Text Available Abstract This paper presents an empirical investigation on the performance of body implant communication using radio frequency (RF technology. In body implant communication, the electrical properties of the body influence the signal propagation in several ways. We use a Perspex body model (30 cm diameter, 80 cm height and 0.5 cm thickness filled with a liquid that mimics the electrical properties of the basic body tissues. This model is used to observe the effects of body tissue on the RF communication. We observe best performance at 3cm depth inside the liquid. We further present a simulation study of several low-power MAC protocols for an on-body sensor network and discuss the derived results. Also, the traditional preamble-based TMDA protocol is extended towards a beacon-based TDMA protocol in order to avoid preamble collision and to ensure low-power communication.

  4. MAC Protocols for GSP in Wireless Sensor Networks

    Directory of Open Access Journals (Sweden)

    Maria Calle

    2008-06-01

    Full Text Available The Gossip-based Sleep Protocol (GSP is a routing protocol designed to save energy in Wireless Sensor Networks. This work presents two MAC protocols designed to complement the characteristics of GSP: MACGSP1 and MACGSP2 were evaluated in combination with GSP on square grids of 100, 400 and 900 simulated nodes. Both protocols show increased energy savings compared to GSP by itself. MACGSP1 provided the greatest energy savings, however MACGSP2 exhibited the best trade off between overhead, delay and packet reception probability. MACGSP2 reduces the duplicate packets generated by GSP, with no significant difference in end-to end delay and a reduced GSP packet reception probability of 10%.

  5. Interference Analysis Status and Plans for Aeronautical Mobile Airport Communications System (AeroMACS)

    Science.gov (United States)

    Kerczewski, Robert J.; Wilson, Jeffrey D.

    2010-01-01

    Interference issues related to the operation of an aeronautical mobile airport communications system (AeroMACS) in the C-Band (specifically 5091-5150 MHz) is being investigated. The issue of primary interest is co-channel interference from AeroMACS into mobile-satellite system (MSS) feeder uplinks. The effort is focusing on establishing practical limits on AeroMACS transmissions from airports so that the threshold of interference into MSS is not exceeded. The analyses are being performed with the software package Visualyse Professional, developed by Transfinite Systems Limited. Results with omni-directional antennas and plans to extend the models to represent AeroMACS more accurately will be presented. These models should enable realistic analyses of emerging AeroMACS designs to be developed from NASA Test Bed, RTCA 223, and European results.

  6. Reliable Multicast MAC Protocol for IEEE 802.11 Wireless LANs with Extended Service Range

    Science.gov (United States)

    Choi, Woo-Yong

    2011-11-01

    In this paper, we propose the efficient reliable multicast MAC protocol by which the AP (Access Point) can transmit reliably its multicast data frames to the recipients in the AP's one-hop or two-hop transmission range. The AP uses the STAs (Stations) that are directly associated with itself as the relays for the data delivery to the remote recipients that cannot be reached directly from itself. Based on the connectivity information among the recipients, the reliable multicast MAC protocol optimizes the number of the RAK (Request for ACK) frame transmissions in a reasonable computational time. Numerical examples show that our proposed MAC protocol significantly enhances the MAC performance compared with the BMMM (Batch Mode Multicast MAC) protocol that is extended to support the recipients that are in the AP's one-hop or two-hop transmission range in IEEE 802.11 wireless LANs.

  7. The identification of MacSe in Streptococcus equi ssp. equi

    Institute of Scientific and Technical Information of China (English)

    Jiande YANG; Yanfei LIU; Jun XU; Jifei MA

    2009-01-01

    Streptococcus equi subsp, equi (S. equi ssp. equi) causes equine strangles, a highly contagious and widespread purulent lymphadenitis of the head and neck. We have identified MacSe, a novel protein of S. equi, by screening a phage library of 3-8 kb random DNA fragments of S. equi CF32. MacSe shares 62% and 67.5% amino acid homology with Mac5005 and Mac8345 of S. pyogenes respectively. Expression during infection was shown by strong reactivity of the protein with convalescent sera and mucosal wash IgA of ponies infected by commingling exposure. Release into the culture medium was detected during the log phase of growth. Dose dependent anti-phagocytic activity for equine neutrophils involved interaction of MacSe with C3 and neutrophils.

  8. Self-Adaptive and Energy-Efficient MAC Protocol Based on Event-Driven

    Directory of Open Access Journals (Sweden)

    Xin Hou

    2013-01-01

    Full Text Available Combined with WSN MAC layer protocol characteristics and design requirements, according to the characteristic of WSN monitoring application requirements, this paper puts forward a method based on event driven MAC protocol. The agreement algorithm is to solve the problem of network congestion and node energy unnecessary consumption cause by a large number of redundant monitoring data transceiver. It is a kind of adaptive low power consumption of the MAC layer protocol, which is pointed out based on theoretical foundation of S_MAC protocol, made use of the event driven mechanism system theory, combined with event driven mechanism and the characteristics of the WSN. It has the periodic dormancy mechanism of S_MAC protocol, in the premise of the reliability data, to reduce data redundancy and communication delay time, improve the overall network throughput, to ensure the safety and reliability of the network, which can greatly extends  the node of working time.

  9. Energy efficient TDMA-based MAC protocol associated with GAF for wireless sensor networks

    Institute of Scientific and Technical Information of China (English)

    XIAO Xiao; ZHENG Bao-yu; YAN Zhen-ya; CHEN Chao

    2007-01-01

    The design of media access control (MAC) protocol for wireless sensor networks (WSNs) with the idea of cross layer attracts more and more attention. People can improve the MAC protocol by obtaining certain information regarding the network layer and physical layer. This article synthesizes and optimizes certain cross-layer protocols which have existed. On the basis of the routing, topology information in the network layer, and transmission power information in the physical layer, the time slot assignment algorithm has been improved in the MAC layer.By using geographical adaptive fidelity algorithm (GAF) to divide the grids, controlling of transmission power and scheduling the work/sleep duty cycle for sensor nodes, a new MAC protocol has been proposed to decrease energy consumption and enlarge the lifetime of WSNs. Simulation results show that the MAC protocol functions well.

  10. Research on low-latency MAC protocols for wireless sensor networks

    Science.gov (United States)

    He, Chenguang; Sha, Xuejun; Lee, Chankil

    2007-11-01

    Energy-efficient should not be the only design goal in MAC protocols for wireless sensor networks, which involve the use of battery-operated computing and sensing devices. Low-latency operation becomes the same important as energy-efficient in the case that the traffic load is very heavy or the real-time constrain is used in applications like tracking or locating. This paper introduces some causes of traditional time delays which are inherent in a multi-hops network using existing WSN MAC protocols, illuminates the importance of low-latency MAC design for wireless sensor networks, and presents three MACs as examples of low-latency protocols designed specially for sleep delay, wait delay and wakeup delay in wireless sensor networks, respectively. The paper also discusses design trade-offs with emphasis on low-latency and points out their advantages and disadvantages, together with some design considerations and suggestions for MAC protocols for future applications and researches.

  11. An Energy-Efficient, Application-Oriented Control Algorithm for MAC Protocols in WSN

    Science.gov (United States)

    Li, Deliang; Peng, Fei; Qian, Depei

    Energy efficiency has been a main concern in wireless sensor networks where Medium Access Control (MAC) protocol plays an important role. However, current MAC protocols designed for energy saving have seldom considered multiple applications coexisting in WSN with variation of traffic load dynamics and different QoS requirements. In this paper, we propose an adaptive control algorithm at MAC layer to promote energy efficiency. We focus on the tradeoff relation between collisions and control overhead as a reflection of traffic load and propose to balance the tradeoff under the constraints of QoS options. We integrate the algorithm into S-MAC and verify it through NS-2 platform. The results demonstrate the algorithm achieves observable improvement in energy performance while meeting QoS requirement for different coexisting applications in comparison with S-MAC.

  12. MicMac GIS application: free open source

    Science.gov (United States)

    Duarte, L.; Moutinho, O.; Teodoro, A.

    2016-10-01

    The use of Remotely Piloted Aerial System (RPAS) for remote sensing applications is becoming more frequent as the technologies on on-board cameras and the platform itself are becoming a serious contender to satellite and airplane imagery. MicMac is a photogrammetric tool for image matching that can be used in different contexts. It is an open source software and it can be used as a command line or with a graphic interface (for each command). The main objective of this work was the integration of MicMac with QGIS, which is also an open source software, in order to create a new open source tool applied to photogrammetry/remote sensing. Python language was used to develop the application. This tool would be very useful in the manipulation and 3D modelling of a set of images. The main objective was to create a toolbar in QGIS with the basic functionalities with intuitive graphic interfaces. The toolbar is composed by three buttons: produce the points cloud, create the Digital Elevation Model (DEM) and produce the orthophoto of the study area. The application was tested considering 35 photos, a subset of images acquired by a RPAS in the Aguda beach area, Porto, Portugal. They were used in order to create a 3D terrain model and from this model obtain an orthophoto and the corresponding DEM. The code is open and can be modified according to the user requirements. This integration would be very useful in photogrammetry and remote sensing community combined with GIS capabilities.

  13. Mac-1 Regulates IL-13 Activity in Macrophages by Directly Interacting with IL-13Rα1.

    Science.gov (United States)

    Cao, Chunzhang; Zhao, Juanjuan; Doughty, Emily K; Migliorini, Mary; Strickland, Dudley K; Kann, Maricel G; Zhang, Li

    2015-08-28

    Mac-1 exhibits a unique inhibitory activity toward IL-13-induced JAK/STAT activation and thereby regulates macrophage to foam cell transformation. However, the underlying molecular mechanism is unknown. In this study, we report the identification of IL-13Rα1, a component of the IL-13 receptor (IL-13R), as a novel ligand of integrin Mac-1, using a co-evolution-based algorithm. Biochemical analyses demonstrated that recombinant IL-13Rα1 binds Mac-1 in a purified system and supports Mac-1-mediated cell adhesion. Co-immunoprecipitation experiments revealed that endogenous Mac-1 forms a complex with IL-13Rα1 in solution, and confocal fluorescence microscopy demonstrated that these two receptors co-localize with each other on the surface of macrophages. Moreover, we found that genetic inactivation of Mac-1 promotes IL-13-induced JAK/STAT activation in macrophages, resulting in enhanced polarization along the alternative activation pathway. Importantly, we observed that Mac-1(-/-) macrophages exhibit increased expression of foam cell differentiation markers including 15-lipoxygenase and lectin-type oxidized LDL receptor-1 both in vitro and in vivo. Indeed, we found that Mac-1(-/-)LDLR(-/-) mice develop significantly more foam cells than control LDLR(-/-) mice, using an in vivo model of foam cell formation. Together, our data establish for the first time a molecular mechanism by which Mac-1 regulates the signaling activity of IL-13 in macrophages. This newly identified IL-13Rα1/Mac-1-dependent pathway may offer novel targets for therapeutic intervention in the future.

  14. Mac-1 Regulates IL-13 Activity in Macrophages by Directly Interacting with IL-13Rα1*

    Science.gov (United States)

    Cao, Chunzhang; Zhao, Juanjuan; Doughty, Emily K.; Migliorini, Mary; Strickland, Dudley K.; Kann, Maricel G.; Zhang, Li

    2015-01-01

    Mac-1 exhibits a unique inhibitory activity toward IL-13-induced JAK/STAT activation and thereby regulates macrophage to foam cell transformation. However, the underlying molecular mechanism is unknown. In this study, we report the identification of IL-13Rα1, a component of the IL-13 receptor (IL-13R), as a novel ligand of integrin Mac-1, using a co-evolution-based algorithm. Biochemical analyses demonstrated that recombinant IL-13Rα1 binds Mac-1 in a purified system and supports Mac-1-mediated cell adhesion. Co-immunoprecipitation experiments revealed that endogenous Mac-1 forms a complex with IL-13Rα1 in solution, and confocal fluorescence microscopy demonstrated that these two receptors co-localize with each other on the surface of macrophages. Moreover, we found that genetic inactivation of Mac-1 promotes IL-13-induced JAK/STAT activation in macrophages, resulting in enhanced polarization along the alternative activation pathway. Importantly, we observed that Mac-1−/− macrophages exhibit increased expression of foam cell differentiation markers including 15-lipoxygenase and lectin-type oxidized LDL receptor-1 both in vitro and in vivo. Indeed, we found that Mac-1−/−LDLR−/− mice develop significantly more foam cells than control LDLR−/− mice, using an in vivo model of foam cell formation. Together, our data establish for the first time a molecular mechanism by which Mac-1 regulates the signaling activity of IL-13 in macrophages. This newly identified IL-13Rα1/Mac-1-dependent pathway may offer novel targets for therapeutic intervention in the future. PMID:26160172

  15. Defining the Anthropocene

    Science.gov (United States)

    Lewis, Simon; Maslin, Mark

    2016-04-01

    Time is divided by geologists according to marked shifts in Earth's state. Recent global environmental changes suggest that Earth may have entered a new human-dominated geological epoch, the Anthropocene. Should the Anthropocene - the idea that human activity is a force acting upon the Earth system in ways that mean that Earth will be altered for millions of years - be defined as a geological time-unit at the level of an Epoch? Here we appraise the data to assess such claims, first in terms of changes to the Earth system, with particular focus on very long-lived impacts, as Epochs typically last millions of years. Can Earth really be said to be in transition from one state to another? Secondly, we then consider the formal criteria used to define geological time-units and move forward through time examining whether currently available evidence passes typical geological time-unit evidence thresholds. We suggest two time periods likely fit the criteria (1) the aftermath of the interlinking of the Old and New Worlds, which moved species across continents and ocean basins worldwide, a geologically unprecedented and permanent change, which is also the globally synchronous coolest part of the Little Ice Age (in Earth system terms), and the beginning of global trade and a new socio-economic "world system" (in historical terms), marked as a golden spike by a temporary drop in atmospheric CO2, centred on 1610 CE; and (2) the aftermath of the Second World War, when many global environmental changes accelerated and novel long-lived materials were increasingly manufactured, known as the Great Acceleration (in Earth system terms) and the beginning of the Cold War (in historical terms), marked as a golden spike by the peak in radionuclide fallout in 1964. We finish by noting that the Anthropocene debate is politically loaded, thus transparency in the presentation of evidence is essential if a formal definition of the Anthropocene is to avoid becoming a debate about bias. The

  16. OTRA-THS MAC to reduce Power Outage Data Collection Latency in a smart meter network

    Energy Technology Data Exchange (ETDEWEB)

    Garlapati, Shravan K [ORNL; Kuruganti, Phani Teja [ORNL; Buehrer, Richard M [ORNL; Reed, Jeffrey H [ORNL

    2014-01-01

    The deployment of advanced metering infrastructure by the electric utilities poses unique communication challenges, particularly as the number of meters per aggregator increases. During a power outage, a smart meter tries to report it instantaneously to the electric utility. In a densely populated residential/industrial locality, it is possible that a large number of smart meters simultaneously try to get access to the communication network to report the power outage. If the number of smart meters is very high of the order of tens of thousands (metropolitan areas), the power outage data flooding can lead to Random Access CHannel (RACH) congestion. Several utilities are considering the use of cellular network for smart meter communications. In 3G/4G cellular networks, RACH congestion not only leads to collisions, retransmissions and increased RACH delays, but also has the potential to disrupt the dedicated traffic flow by increasing the interference levels (3G CDMA). In order to overcome this problem, in this paper we propose a Time Hierarchical Scheme (THS) that reduces the intensity of power outage data flooding and power outage reporting delay by 6/7th, and 17/18th when compared to their respective values without THS. Also, we propose an Optimum Transmission Rate Adaptive (OTRA) MAC to optimize the latency in power outage data collection. The analysis and simulation results presented in this paper show that both the OTRA and THS features of the proposed MAC results in a Power Outage Data Collection Latency (PODCL) that is 1/10th of the 4G LTE PODCL.

  17. Defining Legal Moralism

    DEFF Research Database (Denmark)

    Thaysen, Jens Damgaard

    2015-01-01

    This paper discusses how legal moralism should be defined. It is argued that legal moralism should be defined as the position that “For any X, it is always a pro tanto reason for justifiably imposing legal regulation on X that X is morally wrong (where “morally wrong” is not conceptually equivalent...

  18. MacWillia ms Identities of Linear Codes Over Ring R+vR+v2R%环R+vR+v2 R上线性码的Mac Wi lli ams恒等式

    Institute of Scientific and Technical Information of China (English)

    朱士信; 黄磊

    2016-01-01

    By constructing gray map,linear codes over ring R+vR+v2 R are studied.The Lee weight and several clas-ses of weight enumerators about linear codes over ring R+vR+v2 R are defined,the MacWilliams identities of weight distri-butions between the linear codes and their dual codes over ring R+vR+v2 R are given.According to these identities,we can get the weight distributions of dual codes directly without obtaining the dual codes of linear codes over ring R+vR+v2 R.%通过构造Gray映射,对环R+vR+v2 R上线性码进行了研究。定义了环R+vR+v2 R上线性码的Lee重量及其几类重量计数器,给出了环R+vR+v2 R上线性码及其对偶码之间的各种重量分布的MacWilliams恒等式。利用这些恒等式,不用求出环R+vR+v2 R上线性码的对偶码便可得到对偶码的各种重量分布。

  19. History-based MAC Protocol for Low Duty-Cycle Wireless Sensor Networks: the SLACK-MAC Protocol

    Directory of Open Access Journals (Sweden)

    Affoua Thérèse Aby

    2016-06-01

    Full Text Available Wireless sensor networks (WSNs are increasingly used in environmental monitoring applications. They are designed to operate for several months by featuring low activity cycles in order to save energy. In this paper, we propose a Medium Access Control (MAC protocol for suchWSNs with very low duty-cycles of 1% and less. Nodes are activated randomly and use a history of previous successful frame exchanges to decide their next activation time. We study the choice of the history size, and we compare the performance of our protocol with other protocols from the literature. We show by simulations and real experiments that with a limited history size of only six entries, our protocol achieves better performance than other protocols from the literature, while keeping the advantages of fully asynchronous protocols.

  20. 低占空比无线传感器网络同步 MAC 协议最优信标间隔分析%The Optimal Beacon Interval for Synchronous MAC in Low Duty-Cycle Wireless Sensor Networks

    Institute of Scientific and Technical Information of China (English)

    邢宇龙; 陈永锐; 易卫东; 段成华

    2016-01-01

    Energy efficiency is a fundamental theme in the design of wireless sensor networks protocols ,especially for medium access control (MAC) protocols .An energy‐efficient MAC protocol can significantly elongate the lifetime of wireless sensor networks by reducing the duty‐cycle of sensor nodes to an ultra‐low level .Synchronous MAC can be even more efficient in data transfer at the cost of requiring tight time synchronization through periodical beacon dissemination . The length of the beacon interval may greatly affect the energy efficiency of a synchronous MAC .A shorter beacon interval leads to higher synchronization cost due to frequent beacon sending and receiving ,while a longer beacon interval will lead to a larger guard time and longer idle listening due to clock drift . Therefore ,there is a tradeoff between these two parts of energy consumption .In this paper ,we investigate the optimal beacon interval for synchronous MAC in low duty‐cycle sensor networks ,and then present a strategy that adaptively utilizes the optimal beacon interval in a TDMA‐based MAC protocol (called Opt‐TDMA) .By configuring the beacon interval to its optimal value according to the data packets rate and network size ,Opt‐TDMA can reduce the overall power consumption of both sending/receiving beacons and data packets . Experimental results demonstrate that Opt‐TDMA is more energy‐efficient than pure TDMA protocol and SCP‐MAC by using optimal beacon interval and contention‐free transmission .%能量效率是无线传感器网络协议设计的首要考虑因素。无线传感器网络中,介质访问控制层(medium access control ,MAC)协议通过降低节点的占空比来降低网络能耗,延长网络的生命周期。相比其他 MAC 协议,尽管同步 MAC 需要周期性分发信标来保持严格的时间同步,但却在数据传输方面具有更高的能量效率。信标间隔的长短直接影响同步 M AC 能量效率的高低。一方面

  1. Environmental Assessment for Construction of Security Forces Facility/Demolition of Existing Building 528 MacDill AFB, Florida

    Science.gov (United States)

    2005-08-01

    Gennarro and Tish Maddy MacDill Air Force Base Environmental Restoration Program 7621 Hillsborough Loop Dr. MacDill AFB, FL 33621-5207 Bryan...MacDill Air Force Base Maddy, Tish Lead-based Paint and Asbestos Records, Building 528. Verbal correspondence, February 1, 2005. Naval

  2. 42 CFR 405.1140 - MAC review of ALJ decision in a case remanded by a Federal district court.

    Science.gov (United States)

    2010-10-01

    ... 42 Public Health 2 2010-10-01 2010-10-01 false MAC review of ALJ decision in a case remanded by a...) Medicare Appeals Council Review § 405.1140 MAC review of ALJ decision in a case remanded by a Federal... district court for further consideration and the MAC remands the case to an ALJ, a decision subsequently...

  3. 42 CFR 405.1062 - Applicability of local coverage determinations and other policies not binding on the ALJ and MAC.

    Science.gov (United States)

    2010-10-01

    ... other policies not binding on the ALJ and MAC. 405.1062 Section 405.1062 Public Health CENTERS FOR... of local coverage determinations and other policies not binding on the ALJ and MAC. (a) ALJs and the MAC are not bound by LCDs, LMRPs, or CMS program guidance, such as program memoranda and manual...

  4. On defining dietary fibre.

    Science.gov (United States)

    DeVries, Jonathan W

    2003-02-01

    Establishing a definition for dietary fibre has historically been a balance between nutrition knowledge and analytical method capabilities. While the most widely accepted physiologically-based definitions have generally been accurate in defining the dietary fibre in foods, scientists and regulators have tended, in practice, to rely on analytical procedures as the definitional basis in fact. As a result, incongruities between theory and practice have resulted in confusion regarding the components that make up dietary fibre. In November 1998 the president of the American Association of Cereal Chemists (AACC) appointed an expert scientific review committee and charged it with the task of reviewing and, if necessary, updating the definition of dietary fibre. The committee was further charged with assessing the state of analytical methodology and making recommendations relevant to the updated definition. After due deliberation, an updated definition of dietary fibre was delivered to the AACC Board of Directors for consideration and adoption (Anon, 2000; Jones 2000b). The updated definition includes the same food components as the historical working definition used for approximately 30 years (a very important point, considering that the majority of the research of the past 30 years delineating the positive health effects of dietary fibre is based on that working definition). However, the updated definition more clearly delineates the make-up of dietary fibre and its physiological functionality. As a result, relatively few changes will be necessary in analytical methodology. Current methodologies, in particular AACC-approved method of analysis 32-05 (Grami, 2000), Association of Official Analytical Chemists' official method of analysis 985.29 (Horwitz, 2000a) or AACC 32-07 (Grami, 2000) Association of Official Analytical Chemists 991.43 (Horwitz, 2000a) will continue to be sufficient and used for most foods. A small number of additional methods will be necessary to

  5. A Priority-Based Adaptive MAC Protocol for Wireless Body Area Networks

    Directory of Open Access Journals (Sweden)

    Sabin Bhandari

    2016-03-01

    Full Text Available In wireless body area networks (WBANs, various sensors and actuators are placed on/inside the human body and connected wirelessly. WBANs have specific requirements for healthcare and medical applications, hence, standard protocols like the IEEE 802.15.4 cannot fulfill all the requirements. Consequently, many medium access control (MAC protocols, mostly derived from the IEEE 802.15.4 superframe structure, have been studied. Nevertheless, they do not support a differentiated quality of service (QoS for the various forms of traffic coexisting in a WBAN. In particular, a QoS-aware MAC protocol is essential for WBANs operating in the unlicensed Industrial, Scientific, and Medical (ISM bands, because different wireless services like Bluetooth, WiFi, and Zigbee may coexist there and cause severe interference. In this paper, we propose a priority-based adaptive MAC (PA-MAC protocol for WBANs in unlicensed bands, which allocates time slots dynamically, based on the traffic priority. Further, multiple channels are effectively utilized to reduce access delays in a WBAN, in the presence of coexisting systems. Our performance evaluation results show that the proposed PA-MAC outperforms the IEEE 802.15.4 MAC and the conventional priority-based MAC in terms of the average transmission time, throughput, energy consumption, and data collision ratio.

  6. A Priority-Based Adaptive MAC Protocol for Wireless Body Area Networks.

    Science.gov (United States)

    Bhandari, Sabin; Moh, Sangman

    2016-03-18

    In wireless body area networks (WBANs), various sensors and actuators are placed on/inside the human body and connected wirelessly. WBANs have specific requirements for healthcare and medical applications, hence, standard protocols like the IEEE 802.15.4 cannot fulfill all the requirements. Consequently, many medium access control (MAC) protocols, mostly derived from the IEEE 802.15.4 superframe structure, have been studied. Nevertheless, they do not support a differentiated quality of service (QoS) for the various forms of traffic coexisting in a WBAN. In particular, a QoS-aware MAC protocol is essential for WBANs operating in the unlicensed Industrial, Scientific, and Medical (ISM) bands, because different wireless services like Bluetooth, WiFi, and Zigbee may coexist there and cause severe interference. In this paper, we propose a priority-based adaptive MAC (PA-MAC) protocol for WBANs in unlicensed bands, which allocates time slots dynamically, based on the traffic priority. Further, multiple channels are effectively utilized to reduce access delays in a WBAN, in the presence of coexisting systems. Our performance evaluation results show that the proposed PA-MAC outperforms the IEEE 802.15.4 MAC and the conventional priority-based MAC in terms of the average transmission time, throughput, energy consumption, and data collision ratio.

  7. A tale of two mitochondrial channels, MAC and PTP, in apoptosis.

    Science.gov (United States)

    Kinnally, Kathleen W; Antonsson, Bruno

    2007-05-01

    The crucial step in the intrinsic, or mitochondrial, apoptotic pathway is permeabilization of the mitochondrial outer membrane. Permeabilization triggers release of apoptogenic factors, such as cytochrome c, from the mitochondrial intermembrane space into the cytosol where these factors ensure propagation of the apoptotic cascade and execution of cell death. However, the mechanism(s) underlying permeabilization of the outer membrane remain controversial. Two mechanisms, involving opening of two different mitochondrial channels, have been proposed to be responsible for the permeabilization; the permeability transition pore (PTP) in the inner membrane and the mitochondrial apoptosis-induced channel (MAC) in the outer membrane. Opening of PTP would lead to matrix swelling, subsequent rupture of the outer membrane, and an unspecific release of intermembrane proteins into the cytosol. However, many believe PTP opening is a consequence of apoptosis and this channel is thought to principally play a role in necrosis, not apoptosis. Activation of MAC is exquisitely regulated by Bcl-2 family proteins, which are the sentinels of apoptosis. MAC provides specific pores in the outer membrane for the passage of intermembrane proteins, in particular cytochrome c, to the cytosol. The electrophysiological characteristics of MAC are very similar to Bax channels and depletion of Bax significantly diminishes MAC activity, suggesting that Bax is an essential constituent of MAC in some systems. The characteristics of various mitochondrial channels and Bax are compared. The involvement of MAC and PTP activities in apoptosis of disease and their pharmacology are discussed.

  8. A cross-layer duty cycle MAC protocol supporting a pipeline feature for wireless sensor networks.

    Science.gov (United States)

    Tong, Fei; Xie, Rong; Shu, Lei; Kim, Young-Chon

    2011-01-01

    Although the conventional duty cycle MAC protocols for Wireless Sensor Networks (WSNs) such as RMAC perform well in terms of saving energy and reducing end-to-end delivery latency, they were designed independently and require an extra routing protocol in the network layer to provide path information for the MAC layer. In this paper, we propose a new cross-layer duty cycle MAC protocol with data forwarding supporting a pipeline feature (P-MAC) for WSNs. P-MAC first divides the whole network into many grades around the sink. Each node identifies its grade according to its logical hop distance to the sink and simultaneously establishes a sleep/wakeup schedule using the grade information. Those nodes in the same grade keep the same schedule, which is staggered with the schedule of the nodes in the adjacent grade. Then a variation of the RTS/CTS handshake mechanism is used to forward data continuously in a pipeline fashion from the higher grade to the lower grade nodes and finally to the sink. No extra routing overhead is needed, thus increasing the network scalability while maintaining the superiority of duty-cycling. The simulation results in OPNET show that P-MAC has better performance than S-MAC and RMAC in terms of packet delivery latency and energy efficiency.

  9. Defining Documentary Film

    DEFF Research Database (Denmark)

    Juel, Henrik

    2006-01-01

    A discussion of various attemts at defining documentary film regarding form, content, truth, stile, genre or reception - and a propoposal of a positive list of essential, but non-exclusive characteristica of documentary film......A discussion of various attemts at defining documentary film regarding form, content, truth, stile, genre or reception - and a propoposal of a positive list of essential, but non-exclusive characteristica of documentary film...

  10. Definably amenable NIP groups

    OpenAIRE

    Chernikov, Artem; Simon, Pierre

    2015-01-01

    We study definably amenable NIP groups. We develop a theory of generics, showing that various definitions considered previously coincide, and study invariant measures. Applications include: characterization of regular ergodic measures, a proof of the conjecture of Petrykowski connecting existence of bounded orbits with definable amenability in the NIP case, and the Ellis group conjecture of Newelski and Pillay connecting the model-theoretic connected component of an NIP group with the ideal s...

  11. DLD-MAC:A Diffserv-based Low-delay MAC Protocol for WSNs%DLD-MAC:一种区分服务的低时延传感器网络MAC协议

    Institute of Scientific and Technical Information of China (English)

    舒俊浩; 白光伟; 沈航

    2012-01-01

    针对现有无线传感器网络MAC协议不能提供区分服务和传输时廷较大的问题,在经典多跳传输协议DW-MAC的基础上,提出了一种具有区分服务功能的低时延MAC协议—DLD-MAC(Diffserv-based Low-Delay MAC).其基本思路是让高优先级数据选择更小的竞争窗口,以降低时延和能耗.Markov建模分析表明,DLD-MAC能对不同优先级的业务流进行很好的服务区分,而且相较于传统的无线传感器网络MAC协议,其在时延性能上有显著优势,能更有效地保障服务质量.%Considering that most of the existing MAC protocols in wireless sensor networks do not support any priority scheme,this paper proposed a novel,Diffserv-based low-delay MAC mechanismCDLD-MAC),on the basis of the existing DW-MAC protocol. The main idea is that, by introducing differentiated services, the high priority data chooses smaller back-off window, so that it can achieve much more chance to be delivered, and its packet transmission latency and energy consumption can be reduced significantly compared with low priority data. On the other hand, a Markov chain model was designed in this work, to analyze and evaluate the mechanism performance. Our analytical analyses show that the proposed DLD-MAC can effectively make the high priority data achieve higher QoS over the low priority data, and achieve much lower transmission latency than traditional MAC protocol as well,which is adequate to serve delay-sensitive data flow.

  12. QoS Support Polling Scheme for Multimedia Traffic in Wireless LAN MAC Protocol

    Institute of Scientific and Technical Information of China (English)

    YANG Zhijun; ZHAO Dongfeng

    2008-01-01

    Quality of service (QoS) support is a key attribute for multimedia traffic including video, voice, and data in wireless local area networks (LANs) but is limited in 802.11-based wireless LANs. A polling-based scheme called the point coordination function (PCF) was developed for 802.11 LANs to support the trans-mission of multimedia traffic. However, the PCF is not able to meet the desired practical traffic differentiation requirements for real-time data. This paper describes a QoS support polling scheme based on the IEEE 802.11 medium access control (MAC) protocol. The scheme uses a two-level polling mechanism with the QoS classes differentiated by two different access policies. Stations with higher priority traffic such as key or real-time data form the first level and can access the common channel through an exhaustive access policy. Other stations with lower priority traffic form the second level and can access the channel through a gated access policy. A system model based on imbedded Markov chain theory and a generation function were setup to explicitly analyze the mean information packet waiting time of the two-level polling scheme. Theo-retical and simulation results show that the new scheme efficiently differentiates services to guarantee better QoS and system stability.

  13. Interplay between MacDonald and Hall-Littlewood expansions of extended torus superpolynomials

    CERN Document Server

    Mironov, A; Shakirov, Sh; Sleptsov, A

    2012-01-01

    In arXiv:1106.4305 extended superpolynomials were introduced for the torus links T[m,mk+r], which are functions on the entire space of time variables and, at expense of reducing the topological invariance, possess additional algebraic properties, resembling those of the matrix model partition functions and the KP/Toda tau-functions. Not surprisingly, being a suitable extension it actually allows one to calculate the superpolynomials. These functions are defined as expansions into MacDonald polynomials, and their dependence on k is entirely captured by the action of the cut-and-join operator, like in the HOMFLY case. We suggest a simple description of the coefficients in these character expansions, by expanding the initial (at k=0) conditions for the k-evolution into the new auxiliary basis, this time provided by the Hall-Littlewood polynomials, which, hence, play a role in the description of the dual m-evolution. For illustration we list manifest expressions for a few first series, mk\\pm 1, mk\\pm 2, mk\\pm 3. ...

  14. An extended smart utilization medium access control (ESU-MAC) protocol for ad hoc wireless systems

    Science.gov (United States)

    Vashishtha, Jyoti; Sinha, Aakash

    2006-05-01

    The demand for spontaneous setup of a wireless communication system has increased in recent years for areas like battlefield, disaster relief operations etc., where a pre-deployment of network infrastructure is difficult or unavailable. A mobile ad-hoc network (MANET) is a promising solution, but poses a lot of challenges for all the design layers, specifically medium access control (MAC) layer. Recent existing works have used the concepts of multi-channel and power control in designing MAC layer protocols. SU-MAC developed by the same authors, efficiently uses the 'available' data and control bandwidth to send control information and results in increased throughput via decreasing contention on the control channel. However, SU-MAC protocol was limited for static ad-hoc network and also faced the busy-receiver node problem. We present the Extended SU-MAC (ESU-MAC) protocol which works mobile nodes. Also, we significantly improve the scheme of control information exchange in ESU-MAC to overcome the busy-receiver node problem and thus, further avoid the blockage of control channel for longer periods of time. A power control scheme is used as before to reduce interference and to effectively re-use the available bandwidth. Simulation results show that ESU-MAC protocol is promising for mobile, ad-hoc network in terms of reduced contention at the control channel and improved throughput because of channel re-use. Results show a considerable increase in throughput compared to SU-MAC which could be attributed to increased accessibility of control channel and improved utilization of data channels due to superior control information exchange scheme.

  15. An Economic Analysis of MAC Versus WALANT: A Trigger Finger Release Surgery Case Study.

    Science.gov (United States)

    Codding, Jason L; Bhat, Suneel B; Ilyas, Asif M

    2017-07-01

    There has been recent interest in wide awake hand surgery, also referred to as "wide awake local anesthesia with no tourniquet" (WALANT) surgery. Using a model of single trigger finger release (TFR) surgery, a hypothesis was made that WALANT would result in decreased hospital time and cost than patients receiving sedation with monitored anesthetic care (MAC). Consecutive cases of single TFR surgery with MAC were compared with WALANT. All surgeries were performed in the same manner, at the same facility, and by the same surgeon. Total operating room (OR) time, surgical time, recovery time, and anesthesia costs were analyzed. There were 78 patients: 31 MAC and 47 WALANT. The MAC group averaged 27.2 minutes of OR time; the WALANT group averaged 25.2 minutes. The MAC group surgical time was 10.2 minutes versus WALANT of 10.4 minutes. Post-operatively, the MAC group averaged 72.3 minutes in the recovery room compared with WALANT group of 30.2 minutes. Each case performed under MAC had a minimum of excess charges from anesthesia of approximately $105. Patients undergoing single TFR surgery under WALANT trended toward less time in the OR, had similar surgical times, and spent significantly less time in the recovery room, compared with MAC, thereby resulting in less indirect costs. Each MAC case also had minimum direct excess anesthesia charges of $105, which knowingly underestimates overall charges as it excludes material and fixed costs associated with the delivery of anesthesia. Avoiding sedation for high-volume procedures such as TFR may result in significant systemic savings to payers, and in the future with bundling and episode-based payments can become increasingly important to patients, facilities, and surgeons.

  16. PLEIOTROPHIN, A MULTIFUNCTIONAL CYTOKINE AND GROWTH FACTOR, INDUCES LEUKOCYTE RESPONSES THROUGH THE INTEGRIN MAC-1.

    Science.gov (United States)

    Shen, Di; Podolnikova, Nataly P; Yakubenko, Valentin P; Ardell, Christopher L; Balabiyev, Arnat; Ugarova, Tatiana P; Wang, Xu

    2017-09-22

    Pleiotrophin (PTN) is a multifunctional, cationic, glycosaminoglycan-binding cytokine and growth factor involved in numerous physiological and pathological processes, including tissue repair and inflammation-related diseases. PTN has been shown to promote leukocyte responses by inducing their migration and expression of inflammatory cytokines. However, the mechanisms through which PTN mediates these responses remain unclear. Here, we identified the integrin Mac-1 (αMβ2, CD11b/CD18) as the receptor mediating macrophage adhesion and migration to PTN. We also found that expression of Mac-1 on the surface of human embryonic kidney (HEK) 293 cells induced their adhesion and migration to PTN. Accordingly, PTN promoted Mac-1-dependent cell spreading and initiated intracellular signaling manifested in phosphorylation of Erk1/2. While binding to PTN, Mac-1 on Mac-1-expressing HEK293 cells appear to cooperate with cell-surface proteoglycans, since both anti-Mac-1 function-blocking mAb and heparin were required to block adhesion. Moreover, biolayer interferometry and NMR indicated a direct interaction between the αMI domain, the major ligand-binding region of Mac-1, and PTN. Using peptide libraries, we found that in PTN, the αMI domain bound sequences enriched in basic and hydrophobic residues, indicating that PTN conforms to the general principle of ligand-recognition specificity of the αMI domain toward cationic proteins/peptides. Finally, using recombinant PTN-derived fragments, we show that PTN contains two distinct Mac-1-binding sites in each of its constitutive domains. Collectively, these results identify PTN as a ligand for the integrin Mac-1 on the surface of leukocytes and suggest that this interaction may play a role in inflammatory responses. Copyright © 2017, The American Society for Biochemistry and Molecular Biology.

  17. Measurements of the Sunyaev-Zel'dovich Effect in MACS J0647.7+7015 and MACS J1206.2-0847 at High Angular Resolution with MUSTANG

    CERN Document Server

    Young, Alexander H; Romero, Charles; Sayers, Jack; Balestra, Italo; Clarke, Tracy E; Czakon, Nicole; Devlin, Mark; Dicker, Simon R; Ferrari, Chiara; Girardi, Marisa; Golwala, Sunil; Intema, Huib; Korngut, Phillip M; Mason, Brian S; Mercurio, Amata; Nonino, Mario; Reese, Erik D; Rosati, Piero; Sarazin, Craig; Umetsu, Keiichi

    2014-01-01

    We present high resolution (9$^{\\prime \\prime}$) imaging of the Sunyaev-Zel'dovich Effect (SZE) toward two massive galaxy clusters, MACS J0647.7+7015 ($z=0.591$) and MACS J1206.2-0847 ($z=0.439$). We compare these 90 GHz measurements, taken with the MUSTANG receiver on the Green Bank Telescope, with generalized Navarro-Frenk-White (gNFW) models derived from Bolocam 140 GHz SZE data as well as maps of the thermal gas derived from {\\it Chandra} X-ray observations. For MACS J0647.7+7015, we find a gNFW profile with core slope parameter $\\gamma= 0.9$ fits the MUSTANG image with $\\chi^{2}_{red}=1.005$ and probability to exceed (PTE) = 0.34. For MACS J1206.2-0847, we find $\\gamma=0.7$, $\\chi^{2}_{red}=0.993$, and PTE = 0.70. In addition, we find a significant ($>$3-$\\sigma$) residual SZE feature in MACS J1206.2-0847 coincident with a group of galaxies identified in VLT data and filamentary structure found in a weak-lensing mass reconstruction. We suggest the detected sub-structure may be the SZE decrement from a lo...

  18. A Study on the Distributed Antenna Based Heterogeneous Cognitive Wireless Network Synchronous MAC Protocol

    Directory of Open Access Journals (Sweden)

    Lian-Fen Huang

    2015-01-01

    Full Text Available This paper introduces distributed antennas into a cognitive radio network and presents a heterogeneous network. The best contribution of this paper is that it designs a synchronous cognitive MAC protocol (DAHCWNS-MAC protocol: distributed antenna based heterogeneous cognitive wireless network synchronous MAC protocol. The novel protocol aims at combining the advantages of cognitive radio and distributed antennas to fully utilize the licensed spectrum, broaden the communication range, and improve throughput. This paper carries out the mathematical modeling and performance simulation to demonstrate its superiority in improving the network throughput at the cost of increasing antenna hardware costs.

  19. Approximate discrete time analysis of the hybrid Token-CDMA MAC system

    CSIR Research Space (South Africa)

    Liu, YS

    2007-09-01

    Full Text Available of the Hybrid Token-CDMA MAC System Yi Sheng Liu, Student Member, IEEE, Fambirai Takawira, Member, IEEE , and Hong Jun Xu, Member, IEEE Abstract— In this paper a hybrid Token-CDMA based medium access control (MAC) protocol is considered. The MAC scheme...Zulu-Natal, Howard College Campus. He received the BSc degree in 1984 from the University of Guilin Technology and the MSc degree from the Institute of Telecontrol and Telemeasure in Shi Jian Zhuang, 1989, and the PhD degree from the Beijing University...

  20. Learn AppleScript The Comprehensive Guide to Scripting and Automation on MAC OS X

    CERN Document Server

    Rosenthal, Hanaan

    2009-01-01

    AppleScript is an English-like, easy-to-understand scripting language built into every Mac. AppleScript can automate hundreds of AppleScriptable applications, performing tasks both large and small, complex and simple. Learn AppleScript: The Comprehensive Guide to Scripting and Automation on Mac OS X, Third Edition has been completely updated for Mac OS X Snow Leopard. It's all here, with an emphasis on practical information that will help you solve any automation problem-from the most mundane repetitive tasks to highly integrated workflows of complex systems. * Friendly enough for beginners, d

  1. Differential effect on TCR:CD3 stimulation of a 90-kD glycoprotein (gp90/Mac-2BP), a member of the scavenger receptor cysteine-rich domain protein family

    DEFF Research Database (Denmark)

    Silvestri, B; Calderazzo, F; Coppola, V;

    1998-01-01

    We studied the effects of a 90-kD glycoprotein (gp90/Mac-2BP) belonging to the scavenger receptor family, present in normal serum and at increased levels in inflammatory disease and cancer patients, on some T cell function parameters. Whereas the lymphocyte proliferative response to non-specific ......We studied the effects of a 90-kD glycoprotein (gp90/Mac-2BP) belonging to the scavenger receptor family, present in normal serum and at increased levels in inflammatory disease and cancer patients, on some T cell function parameters. Whereas the lymphocyte proliferative response to non...

  2. MAC Protocol for Ad Hoc Networks Using a Genetic Algorithm

    Directory of Open Access Journals (Sweden)

    Omar Elizarraras

    2014-01-01

    Full Text Available The problem of obtaining the transmission rate in an ad hoc network consists in adjusting the power of each node to ensure the signal to interference ratio (SIR and the energy required to transmit from one node to another is obtained at the same time. Therefore, an optimal transmission rate for each node in a medium access control (MAC protocol based on CSMA-CDMA (carrier sense multiple access-code division multiple access for ad hoc networks can be obtained using evolutionary optimization. This work proposes a genetic algorithm for the transmission rate election considering a perfect power control, and our proposition achieves improvement of 10% compared with the scheme that handles the handshaking phase to adjust the transmission rate. Furthermore, this paper proposes a genetic algorithm that solves the problem of power combining, interference, data rate, and energy ensuring the signal to interference ratio in an ad hoc network. The result of the proposed genetic algorithm has a better performance (15% compared to the CSMA-CDMA protocol without optimizing. Therefore, we show by simulation the effectiveness of the proposed protocol in terms of the throughput.

  3. MAC to VAX Connectivity: Heartrate Spectral Analysis System

    Science.gov (United States)

    Rahman, Hasan H.; Faruque, Monazer

    1993-01-01

    The heart rate Spectral Analysis System (SAS) acquires and analyzes, in real-time, the Space Shuttle onboard electrocardiograph (EKG) experiment signals, calculates the heartrate, and applies a Fast Fourier Transformation (FFT) to the heart rate. The system also calculates other statistical parameters such as the 'mean heart rate' over specific time period and heart rate histogram. This SAS is used by NASA Principal Investigators as a research tool to determine the effects of weightlessness on the human cardiovascular system. This is also used to determine if Lower Body Negative Pressure (LBNP) is an effective countermeasure to the orthostatic intolerance experienced by astronauts upon return to normal gravity. In microgravity, astronauts perform the LBNP experiment in the mid deck of the Space Shuttle. The experiment data are downlinked by the orbiter telemetry system, then processed and analyzed in real-time by the integrated Life Sciences Data Acquisition (LSDS) - Spectral Analysis System. The data system is integrated within the framework of two different computer systems, VAX and Macintosh (Mac), using the networking infrastructure to assist the investigators in further understanding the most complex machine on Earth--the human body.

  4. Tracing the merger history of MACS clusters using the GMRT

    CERN Document Server

    Paul, S; Intema, H T

    2014-01-01

    Galaxy-cluster merger shocks efficiently accelerate the ambient electrons through diffusive shock acceleration and amplify magnetic field by compressing the Inter Cluster Medium. As a result, such objects produce a significant amount of synchrotron radio emission. Radio halo and Mpc scale peripheral radio relics thus help us to trace back the cluster formation history. To study the dynamical state of the galaxy clusters and their relation to the merging scenario, as a pilot project, we thus observed four suitable candidates from the MACS (Massive Cluster Survey) cluster sample. Observations were carried out simultaneously at 610 and 235 MHz with the GMRT. We observed a rare phenomena in the cluster MACSJ0014.3-3022, which hosts both a peripheral spectacular radio relic and an unusually flat spectrum central giant radio halo of more than 1.5 Mpc dimension. We also report that another cluster MACSJ0152.5-2852 is possibly showing the sign of one of the earliest and young merging system where, we saw a faint 0.5 ...

  5. A MAC Protocol to Support Monitoring of Underwater Spaces †

    Science.gov (United States)

    Santos, Rodrigo; Orozco, Javier; Ochoa, Sergio F.; Meseguer, Roc; Eggly, Gabriel; Pistonesi, Marcelo F.

    2016-01-01

    Underwater sensor networks are becoming an important field of research, because of their everyday increasing application scope. Examples of their application areas are environmental and pollution monitoring (mainly oil spills), oceanographic data collection, support for submarine geolocalization, ocean sampling and early tsunamis alert. The challenge of performing underwater communications is well known, provided that radio signals are useless in this medium, and a wired solution is too expensive. Therefore, the sensors in these networks transmit their information using acoustic signals that propagate well under water. This data transmission type not only brings an opportunity, but also several challenges to the implementation of these networks, e.g., in terms of energy consumption, data transmission and signal interference. In order to help advance the knowledge in the design and implementation of these networks for monitoring underwater spaces, this paper proposes a MAC protocol for acoustic communications between the nodes, based on a self-organized time division multiple access mechanism. The proposal was evaluated using simulations of a real monitoring scenario, and the obtained results are highly encouraging. PMID:27355950

  6. A MAC Protocol to Support Monitoring of Underwater Spaces

    Directory of Open Access Journals (Sweden)

    Rodrigo Santos

    2016-06-01

    Full Text Available Underwater sensor networks are becoming an important field of research, because of their everyday increasing application scope. Examples of their application areas are environmental and pollution monitoring (mainly oil spills, oceanographic data collection, support for submarine geolocalization, ocean sampling and early tsunamis alert. The challenge of performing underwater communications is well known, provided that radio signals are useless in this medium, and a wired solution is too expensive. Therefore, the sensors in these networks transmit their information using acoustic signals that propagate well under water. This data transmission type not only brings an opportunity, but also several challenges to the implementation of these networks, e.g., in terms of energy consumption, data transmission and signal interference. In order to help advance the knowledge in the design and implementation of these networks for monitoring underwater spaces, this paper proposes a MAC protocol for acoustic communications between the nodes, based on a self-organized time division multiple access mechanism. The proposal was evaluated using simulations of a real monitoring scenario, and the obtained results are highly encouraging.

  7. A MAC Protocol to Support Monitoring of Underwater Spaces.

    Science.gov (United States)

    Santos, Rodrigo; Orozco, Javier; Ochoa, Sergio F; Meseguer, Roc; Eggly, Gabriel; Pistonesi, Marcelo F

    2016-01-01

    Underwater sensor networks are becoming an important field of research, because of their everyday increasing application scope. Examples of their application areas are environmental and pollution monitoring (mainly oil spills), oceanographic data collection, support for submarine geolocalization, ocean sampling and early tsunamis alert. The challenge of performing underwater communications is well known, provided that radio signals are useless in this medium, and a wired solution is too expensive. Therefore, the sensors in these networks transmit their information using acoustic signals that propagate well under water. This data transmission type not only brings an opportunity, but also several challenges to the implementation of these networks, e.g., in terms of energy consumption, data transmission and signal interference. In order to help advance the knowledge in the design and implementation of these networks for monitoring underwater spaces, this paper proposes a MAC protocol for acoustic communications between the nodes, based on a self-organized time division multiple access mechanism. The proposal was evaluated using simulations of a real monitoring scenario, and the obtained results are highly encouraging.

  8. Emergency Handling for MAC Protocol in Human Body Communication

    Directory of Open Access Journals (Sweden)

    Kwon Youngmi

    2011-01-01

    Full Text Available The human body communication (HBC is a technology that enables short range data communication using the human body as a medium, like an electrical wire. Thus it removes the need for a traditional antenna. HBC may be used as a type of data communication in body area network (BAN, while the devices are being in contact with body. One of important issues in BAN is an emergency alarm because it may be closely related to human life. For emergency data communication, the most critical factor is the time constraint. IEEE 802.15.6 specifies that the emergency alarm for the BAN must be notified in less than 1 sec and must provide prioritization mechanisms for emergency traffic and notification. As one type of BAN, the HBC must follow this recommendation, too. Existing emergency handling methods in BAN are based on the carrier sensing capability on radio frequencies to detect the status of channels. However, PHY protocol in HBC does not provide the carrier sensing. So the previous methods are not well suitable for HBC directly. Additionally, in the environment that the emergency rate is very low, the allocation of dedicated slot(s for emergency in each superframe is very wasteful. In this work, we proposed specific emergency handling operation for human body communication's medium access control (HBC-MAC protocol to meet the emergency requirements for BAN. We also showed the optimal number of emergency slots for the various combinations of beacon intervals and emergency rates.

  9. LAMAN: Load Adaptable MAC for Ad Hoc Networks

    Directory of Open Access Journals (Sweden)

    Realp Marc

    2005-01-01

    Full Text Available In mobile ad hoc radio networks, mechanisms on how to access the radio channel are extremely important in order to improve network efficiency. In this paper, the load adaptable medium access control for ad hoc networks (LAMAN protocol is described. LAMAN is a novel decentralized multipacket MAC protocol designed following a cross-layer approach. Basically, this protocol is a hybrid CDMA-TDMA-based protocol that aims at throughput maximization in multipacket communication environments by efficiently combining contention and conflict-free protocol components. Such combination of components is used to adapt the nodes' access priority to changes on the traffic load while, at the same time, accounting for the multipacket reception (MPR capability of the receivers. A theoretical analysis of the system is developed presenting closed expressions of network throughput and packet delay. By simulations the validity of our analysis is shown and the performances of a LAMAN-based system and an Aloha-CDMA-based one are compared.

  10. Design and Analysis of an Asynchronous Zero Collision MAC Protocol

    CERN Document Server

    Lee, Jiwoong

    2008-01-01

    This paper proposes and analyzes a distributed MAC protocol that achieves zero collision with no control message exchange nor synchronization. ZC (ZeroCollision) is neither reservation-based nor dynamic TDMA; the protocol supports variable-length packets and does not lose efficiency when some of the stations do not transmit. At the same time, ZC is not a CSMA; in its steady state, it is completely collision-free. The stations transmit repeatedly in a round-robin order once the convergence state is reached. If some stations skip their turn, their transmissions are replaced by idle $20 \\mu$-second mini-slots that enable the other stations to keep track of their order. Because of its short medium access delay and its efficiency, the protocol supports both real-time and elastic applications. The protocol allows for nodes leaving and joining the network; it can allocate more throughput to specific nodes (such as an access point). The protocol is robust against carrier sensing errors or clock drift. While collision...

  11. Modified pterional craniotomy without "MacCarty keyhole".

    Science.gov (United States)

    Moscovici, Samuel; Mizrahi, Cezar José; Margolin, Emil; Spektor, Sergey

    2016-02-01

    Pterional craniotomy is one of the most widely used approaches in neurosurgery. The MacCarty keyhole has remained the preferred means of beginning the craniotomy to achieve a low access point; however, the bone opening may result in a residual defect and an aesthetically unpleasant depression in the periorbital area. We present our modification of the traditional technique. Instead of drilling the keyhole in the frontoperiorbital area, the classical location, we perform a 5 × 15 mm strip craniectomy at the lowest accessible point in the infratemporal fossa, corresponding to the projection of the most lateral point of the sphenoid ridge. The anterior half of this opening exposes the basal frontal dura, while the posterior half brings the temporal dura into view. This modified technique was applied in 48 pterional craniotomies performed for removal of a variety of neoplasms during 2014-2015. There were no approach-related complications. Aesthetic outcomes and patient acceptance have been good; no patient developed skin depression in the periorbital area. In our experience, craniotomy for a pterional approach with the lowest possible access to the frontotemporal skull base may be performed by drilling a narrow oblong opening, without the use of any keyhole or burr hole, to create a smaller skull defect and achieve optimal aesthetic outcomes. Copyright © 2015 Elsevier Ltd. All rights reserved.

  12. Can play be defined?

    DEFF Research Database (Denmark)

    Eichberg, Henning

    2015-01-01

    Can play be defined? There is reason to raise critical questions about the established academic demand that at phenomenon – also in humanist studies – should first of all be defined, i.e. de-lineated and by neat lines limited to a “little box” that can be handled. The following chapter develops t....... Human beings can very well understand play – or whatever phenomenon in human life – without defining it........ The academic imperative of definition seems to be linked to the positivistic attempts – and produces sometimes monstrous definitions. Have they any philosophical value for our knowledge of what play is? Definition is not a universal instrument of knowledge-building, but a culturally specific construction...

  13. Nouns to Define Homophobia

    Directory of Open Access Journals (Sweden)

    Adalberto Campo Arias

    2013-09-01

    Full Text Available Background. The term ‘homophobia’ was introduced in the academic context more than 40 years ago. However, its meaning has changed over time. Objective. To review the nouns used in the last twelve years to define homophobia. Methodology. The authors conducted a systematic search in Medline through Pubmed that included editorials, letters to editors, comments and narrative reviews, in English and Spanish. A qualitative analysis (Grounded theory was applied to analyze nouns used to define homophobia since 2001 through 2012. Results. Authors reviewed three papers including ten nouns to define homophobia, the most common noun was fear. The terms were grouped into two domains: negative attitude and discomfort with homosexuality. Conclusion. Fear is the most used word to describe homophobia. The terms were grouped into two domains: negative attitude and discomfort toward homosexuality.

  14. Defining "intermittent UVR exposure"

    DEFF Research Database (Denmark)

    Bodekær, Mette; Philipsen, Peter Alshede; Petersen, Bibi Øager;

    2016-01-01

    to define and quantify “intermittent UVR exposure” by an objective measure. Methods: A broad study population of adults and children had data collected during a summer period. Data were personal UVR dosimetry measurements, from which the number of “intermittent days” was derived, sun behaviour diaries.......001). The corresponding numbers for prediction of nevi and lentigo density by retrospective questionnaire data was lower (R2 = 0.11, R2 = 0.26, p defined objective measure of intermittent UVR exposure. This measure may provide a better prediction of solar skin damage and CMM...

  15. Finding of No Significant Impact and Finding of No Practicable Alternative Construction of a Warehouse Complex MacDill Air Force Base, Florida

    Science.gov (United States)

    2016-06-13

    noise environment is dependent upon the activity that is conducted and the level of annoyance, hearing loss, speech interference, and sleep ...facility would be designed using standard engineering principles and constructed to comply with the MacDill Air Force Base Architectural Compatibility...Florida Architectural Coatings No. Reqd.a NOx VOC b CO SO2 c PM10 Equipment per 10 acres (lb/day) (lb/day) (lb/day) (lb/day) Air Compressor 1 6.83

  16. Analysis of an Adaptive P-Persistent MAC Scheme for WLAN Providing Delay Fairness

    Science.gov (United States)

    Yen, Chih-Ming; Chang, Chung-Ju; Chen, Yih-Shen; Huang, Ching Yao

    The paper proposes and analyzes an adaptive p-persistent-based (APP) medium access control (MAC) scheme for IEEE 802.11 WLAN. The APP MAC scheme intends to support delay fairness for every station in each access, denoting small delay variance. It differentiates permission probabilities of transmission for stations which are incurred with various packet delays. This permission probability is designed as a function of the numbers of retransmissions and re-backoffs so that stations with larger packet delay are endowed with higher permission probability. Also, the scheme is analyzed by a Markov-chain analysis, where the collision probability, the system throughput, and the average delay are successfully obtained. Numerical results show that the proposed APP MAC scheme can attain lower mean delay and higher mean throughput. In the mean time, simulation results are given to justify the validity of the analysis, and also show that the APP MAC scheme can achieve more delay fairness than conventional algorithms.

  17. Corrections to "Connectivity-Based Reliable Multicast MAC Protocol for IEEE 802.11 Wireless LANs"

    Directory of Open Access Journals (Sweden)

    Choi Woo-Yong

    2010-01-01

    Full Text Available We have found the errors in the throughput formulae presented in our paper "Connectivity-based reliable multicast MAC protocol for IEEE 802.11 wireless LANs". We provide the corrected formulae and numerical results.

  18. Evaluation of video transmission of MAC protocols in wireless sensor network

    Science.gov (United States)

    Maulidin, Mahmuddin, M.; Kamaruddin, L. M.; Elsaikh, Mohamed

    2016-08-01

    Wireless Sensor Network (WSN) is a wireless network which consists of sensor nodes scattered in a particular area which are used to monitor physical or environment condition. Each node in WSN is also scattered in sensor field, so an appropriate scheme of MAC protocol should have to develop communication link for data transferring. Video transmission is one of the important applications for the future that can be transmitted with low aspect in side of cost and also power consumption. In this paper, comparison of five different MAC WSN protocol for video transmission namely IEEE 802.11 standard, IEEE 802.15.4 standard, CSMA/CA, Berkeley-MAC, and Lightweight-MAC protocol are studied. Simulation experiment has been conducted in OMNeT++ with INET network simulator software to evaluate the performance. Obtained results indicate that IEEE 802.11 works better than other protocol in term of packet delivery, throughput, and latency.

  19. Adaptive low-power listening MAC protocol based on transmission rates.

    Science.gov (United States)

    Hwang, Kwang-il; Yi, Gangman

    2014-01-01

    Even though existing low-power listening (LPL) protocols have enabled ultra-low-power operation in wireless sensor networks (WSN), they do not address trade-off between energy and delay, since they focused only on energy aspect. However, in recent years, a growing interest in various WSN applications is requiring new design factors, such as minimum delay and higher reliability, as well as energy efficiency. Therefore, in this paper we propose a novel sensor multiple access control (MAC) protocol, transmission rate based adaptive low-power listening MAC protocol (TRA-MAC), which is a kind of preamble-based LPL but is capable of controlling preamble sensing cycle adaptively to transmission rates. Through experiments, it is demonstrated that TRA-MAC enables LPL cycle (LC) and preamble transmission length to adapt dynamically to varying transmission rates, compensating trade-off between energy and response time.

  20. Four new species of Adicella MacLachlan (Trichoptera: Leptoceridae: Triaenodini) from Sabah, East Malaysia

    NARCIS (Netherlands)

    Huisman, J.; Andersen, T.

    1997-01-01

    Four new species of Adicella MacLachlan, 1877, A. anakpanah spec, nov., A. bavanga spec, nov., A. danumensis spec, nov., and A. gada spec, nov., from Sabah (Borneo), East Malaysia, are described and figured.

  1. An Improved MAC Scheme of HORNET Based on Node Structure with Variable Optical Buffer

    Institute of Scientific and Technical Information of China (English)

    Nian Fang; Lutang Wang; Zhaoming Huang

    2003-01-01

    An improved unslotted CSMA/CA MAC scheme of HORNET based on the node structure with variable optical buffer is reported. It can be used for transmitting high effectively all variable IP packets in the WDM network.

  2. Industrial WSN Based on IR-UWB and a Low-Latency MAC Protocol

    Science.gov (United States)

    Reinhold, Rafael; Underberg, Lisa; Wulf, Armin; Kays, Ruediger

    2016-07-01

    Wireless sensor networks for industrial communication require high reliability and low latency. As current wireless sensor networks do not entirely meet these requirements, novel system approaches need to be developed. Since ultra wideband communication systems seem to be a promising approach, this paper evaluates the performance of the IEEE 802.15.4 impulse-radio ultra-wideband physical layer and the IEEE 802.15.4 Low Latency Deterministic Network (LLDN) MAC for industrial applications. Novel approaches and system adaptions are proposed to meet the application requirements. In this regard, a synchronization approach based on circular average magnitude difference functions (CAMDF) and on a clean template (CT) is presented for the correlation receiver. An adapted MAC protocol titled aggregated low latency (ALL) MAC is proposed to significantly reduce the resulting latency. Based on the system proposals, a hardware prototype has been developed, which proves the feasibility of the system and visualizes the real-time performance of the MAC protocol.

  3. Side channel analysis of some hash based MACs:A response to SHA-3 requirements

    DEFF Research Database (Denmark)

    function which is more resistant to known side channel attacks (SCA) when plugged into HMAC, or that has an alternative MAC mode which is more resistant to known SCA than the other submitted alternatives. In response to this, we perform differential power analysis (DPA) on the possible smart card...... implementations of some of the recently proposed MAC alternatives to NMAC (a fully analyzed variant of HMAC) and HMAC algorithms and NMAC/HMAC versions of some recently proposed hash and compression function modes. We show that the recently proposed BNMAC and KMDP MAC schemes are even weaker than NMAC....../HMAC against the DPA attacks, whereas multi-lane NMAC, EMD MAC and the keyed wide-pipe hash have similar security to NMAC against the DPA attacks. Our DPA attacks do not work on the NMAC setting of MDC-2, Grindahl and MAME compression functions. This talk outlines our results....

  4. A Multi-Channel Diversity Based MAC Protocol for Power-Constrained Cognitive Ad Hoc Networks

    CERN Document Server

    Wang, Yichen; Du, Qinghe; Zhang, Chao

    2011-01-01

    One of the major challenges in the medium access control (MAC) protocol design over cognitive Ad Hoc networks (CAHNs) is how to efficiently utilize multiple opportunistic channels, which vary dynamically and are subject to limited power resources. To overcome this challenge, in this paper we first propose a novel diversity technology called \\emph{Multi-Channel Diversity} (MCD), allowing each secondary node to use multiple channels simultaneously with only one radio per node under the upperbounded power. Using the proposed MCD, we develop a MCD based MAC (MCD-MAC) protocol, which can efficiently utilize available channel resources through joint power-channel allocation. Particularly, we convert the joint power-channel allocation to the Multiple-Choice Knapsack Problem, such that we can obtain the optimal transmission strategy to maximize the network throughput through dynamic programming. Simulation results show that our proposed MCD-MAC protocol can significantly increase the network throughput as compared to...

  5. 78 FR 2879 - Federal Agricultural Mortgage Corporation Funding and Fiscal Affairs; Farmer Mac Investment...

    Science.gov (United States)

    2013-01-15

    ..., 2012 (77 FR 66375) is effective December 31, 2012. FOR FURTHER INFORMATION CONTACT: Joseph T. Connor... 3052-AC56 Federal Agricultural Mortgage Corporation Funding and Fiscal Affairs; Farmer Mac...

  6. AN EFFICIENT MAC PROTOCOL BASED ON HYBRID SUPERFRAME FOR WIRELESS SENSOR NETWORKS

    Directory of Open Access Journals (Sweden)

    Ge Ma

    2009-07-01

    Full Text Available Designing low energy consumption, high efficiency Media Access Control (MAC protocols are one ofthe most important directions in wireless sensor networks (WSN. In this paper, we proposed a newcontention reserve MAC protocol, named CRMAC, under the inspiration of IEEE 802.15.4’s superframestructure. CRMAC is a MAC protocol suitable for intra-cluster WSN that combines the advantages ofcontention and schedule-based MAC protocols. We introduce the mechanism and superframe structure ofCRMAC in detail and verified the performance of this protocol through simulations. Our results showthat CRMAC performs better than IEEE 802.15.4 in energy consumption, system delay and networkthroughput. CRMAC is especially suitable for short packet transmission under low load networks, whichis the main situation in WSN.

  7. Experimental Evaluation of Simulation Abstractions for Wireless Sensor Network MAC Protocols

    Directory of Open Access Journals (Sweden)

    G. P. Halkes

    2010-01-01

    Full Text Available The evaluation of MAC protocols for Wireless Sensor Networks (WSNs is often performed through simulation. These simulations necessarily abstract away from reality in many ways. However, the impact of these abstractions on the results of the simulations has received only limited attention. Moreover, many studies on the accuracy of simulation have studied either the physical layer and per link effects or routing protocol effects. To the best of our knowledge, no other work has focused on the study of the simulation abstractions with respect to MAC protocol performance. In this paper, we present the results of an experimental study of two often used abstractions in the simulation of WSN MAC protocols. We show that a simple SNR-based reception model can provide quite accurate results for metrics commonly used to evaluate MAC protocols. Furthermore, we provide an analysis of what the main sources of deviation are and thereby how the simulations can be improved to provide even better results.

  8. On Defining Mass

    Science.gov (United States)

    Hecht, Eugene

    2011-01-01

    Though central to any pedagogical development of physics, the concept of mass is still not well understood. Properly defining mass has proven to be far more daunting than contemporary textbooks would have us believe. And yet today the origin of mass is one of the most aggressively pursued areas of research in all of physics. Much of the excitement…

  9. Defining Data Science

    OpenAIRE

    Zhu, Yangyong; Xiong, Yun

    2015-01-01

    Data science is gaining more and more and widespread attention, but no consensus viewpoint on what data science is has emerged. As a new science, its objects of study and scientific issues should not be covered by established sciences. Data in cyberspace have formed what we call datanature. In the present paper, data science is defined as the science of exploring datanature.

  10. Defining Mathematical Giftedness

    Science.gov (United States)

    Parish, Linda

    2014-01-01

    This theoretical paper outlines the process of defining "mathematical giftedness" for a present study on how primary school teaching shapes the mindsets of children who are mathematically gifted. Mathematical giftedness is not a badge of honour or some special value attributed to a child who has achieved something exceptional.…

  11. Software Defined Networking

    DEFF Research Database (Denmark)

    Caba, Cosmin Marius

    resources are limited. Hence, to counteract this trend, current QoS mechanisms must become simpler to deploy and operate, in order to motivate NSPs to employ QoS techniques instead of overprovisioning. Software Defined Networking (SDN) represents a paradigm shift in the way telecommunication and data...

  12. Defining Effective Teaching

    Science.gov (United States)

    Layne, L.

    2012-01-01

    The author looks at the meaning of specific terminology commonly used in student surveys: "effective teaching." The research seeks to determine if there is a difference in how "effective teaching" is defined by those taking student surveys and those interpreting the results. To investigate this difference, a sample group of professors and students…

  13. Defining Game Mechanics

    DEFF Research Database (Denmark)

    Sicart (Vila), Miguel Angel

    2008-01-01

    This article defins game mechanics in relation to rules and challenges. Game mechanics are methods invoked by agents for interacting with the game world. I apply this definition to a comparative analysis of the games Rez, Every Extend Extra and Shadow of the Colossus that will show the relevance...... of a formal definition of game mechanics. Udgivelsesdato: Dec 2008...

  14. Software Defined Cyberinfrastructure

    Energy Technology Data Exchange (ETDEWEB)

    Foster, Ian; Blaiszik, Ben; Chard, Kyle; Chard, Ryan

    2017-07-17

    Within and across thousands of science labs, researchers and students struggle to manage data produced in experiments, simulations, and analyses. Largely manual research data lifecycle management processes mean that much time is wasted, research results are often irreproducible, and data sharing and reuse remain rare. In response, we propose a new approach to data lifecycle management in which researchers are empowered to define the actions to be performed at individual storage systems when data are created or modified: actions such as analysis, transformation, copying, and publication. We term this approach software-defined cyberinfrastructure because users can implement powerful data management policies by deploying rules to local storage systems, much as software-defined networking allows users to configure networks by deploying rules to switches.We argue that this approach can enable a new class of responsive distributed storage infrastructure that will accelerate research innovation by allowing any researcher to associate data workflows with data sources, whether local or remote, for such purposes as data ingest, characterization, indexing, and sharing. We report on early experiments with this approach in the context of experimental science, in which a simple if-trigger-then-action (IFTA) notation is used to define rules.

  15. Defining Game Mechanics

    DEFF Research Database (Denmark)

    Sicart (Vila), Miguel Angel

    2008-01-01

    This article defins game mechanics in relation to rules and challenges. Game mechanics are methods invoked by agents for interacting with the game world. I apply this definition to a comparative analysis of the games Rez, Every Extend Extra and Shadow of the Colossus that will show the relevance...... of a formal definition of game mechanics. Udgivelsesdato: Dec 2008...

  16. Mac-2 binding protein is a novel E-selectin ligand expressed by breast cancer cells.

    Science.gov (United States)

    Shirure, Venktesh S; Reynolds, Nathan M; Burdick, Monica M

    2012-01-01

    Hematogenous metastasis involves the adhesion of circulating tumor cells to vascular endothelium of the secondary site. We hypothesized that breast cancer cell adhesion is mediated by interaction of endothelial E-selectin with its glycoprotein counter-receptor(s) expressed on breast cancer cells. At a hematogenous wall shear rate, ZR-75-1 breast cancer cells specifically adhered to E-selectin expressing human umbilical vein endothelial cells when tested in parallel plate flow chamber adhesion assays. Consistent with their E-selectin ligand activity, ZR-75-1 cells expressed flow cytometrically detectable epitopes of HECA-452 mAb, which recognizes high efficiency E-selectin ligands typified by sialofucosylated moieties. Multiple E-selectin reactive proteins expressed by ZR-75-1 cells were revealed by immunoprecipitation with E-selectin chimera (E-Ig chimera) followed by Western blotting. Mass spectrometry analysis of the 72 kDa protein, which exhibited the most prominent E-selectin ligand activity, corresponded to Mac-2 binding protein (Mac-2BP), a heretofore unidentified E-selectin ligand. Immunoprecipitated Mac-2BP expressed sialofucosylated epitopes and possessed E-selectin ligand activity when tested by Western blot analysis using HECA-452 mAb and E-Ig chimera, respectively, demonstrating that Mac-2BP is a novel high efficiency E-selectin ligand. Furthermore, silencing the expression of Mac-2BP from ZR-75-1 cells by shRNA markedly reduced their adhesion to E-selectin expressing cells under physiological flow conditions, confirming the functional E-selectin ligand activity of Mac-2BP on intact cells. In addition to ZR-75-1 cells, several other E-selectin ligand positive breast cancer cell lines expressed Mac-2BP as detected by Western blot and flow cytometry, suggesting that Mac-2BP may be an E-selectin ligand in a variety of breast cancer types. Further, invasive breast carcinoma tissue showed co-localized expression of Mac-2BP and HECA-452 antigens by

  17. Achievable rates for transmission of discrete constellations over the Gaussian MAC channe

    CERN Document Server

    Ghaffar, Rizwan; Lee, Jungwon

    2011-01-01

    In this paper we consider the achievable rate region of the Gaussian Multiple Access Channel (MAC) when suboptimal transmission schemes are employed. Focusing on the two-user MAC and assuming uncoded Pulse Amplitude Modulation (PAM), we derive a rate region that is a pentagon, and propose a strategy with which it can be achieved. We also compare the region with outer bounds and with orthogonal transmission.

  18. Performance evaluation of MAC transmission power control in wireless sensor networks.

    OpenAIRE

    Egea López, Estebán

    2007-01-01

    In this paper we provide a method to analytically compute the energy saving provided by the use of Transmission Power Control (TPC) at the MAC layer in Wireless Sensor Networks (WSN). We consider a classical TPC mechanism: data packets are transmitted with the minimum required power to achieve a given packet error probability, whereas the additional MAC control packets are transmitted with the nominal (maximum) power. This scheme has been chosen because it does not modify the network to...

  19. John MacCulloch, MD (1773-1835): a dedicated geologist.

    Science.gov (United States)

    Hull, Gillian

    2007-11-01

    The teaching in Scottish medical schools in the second half of the 18th century had a reputation that stretched far beyond Britain. Edinburgh attracted students not only for its high academic standards but also for its freedom from religious constraints and its developing interest in the sciences. John MacCulloch was taught at Edinburgh by Joseph Black (1728-99) who had chosen chemistry as a career rather than medicine. Already MacCulloch's enquiring mind ranged over many subjects.

  20. FPGA IMPLEMENTATION OF MAC HEADER BLOCK OF TRANSMITTER FOR Wi-Fi

    Directory of Open Access Journals (Sweden)

    A.M.BHAVIKATTI,

    2011-04-01

    Full Text Available For the wireless communication, IEEE 802.11 is one of the protocols available. The IEEE 802.11b uses the medium access control layer (MAC for wireless local area network. These wireless local area networks use Carrier Sense multiple access with collision avoidance (CSMA/CS for the MAC layer .But only the MAC layer for transmitter is considered here for simulation. So, the Wi-Fi transmitter module is divided into 5 blocks i.e. Data Unit Interface block, Controller block, Pay Load Data Storage, MAC Header Register block and Data Processing block. In this paper we consider only the simulation of MAC header register blocks. So, other blocks i.e. Data unit interface block, Controller block, pay load Data Storage block & Data Processing block are not discussed further in this paper. A field programmable gate array (FPGA device has been used as the hardware implementation platform. The proposed MAC-layer hardware is implemented with Xilinx xcv300e Virtex E FPGA.

  1. FPGA IMPLEMENTATION OF MAC HEADER BLOCK OF TRANSMITTER FOR Wi-Fi

    Directory of Open Access Journals (Sweden)

    A.M.BHAVIKATTI,

    2011-04-01

    Full Text Available For the wireless communication, IEEE 802.11 is one of the protocols available. The IEEE 802.11b uses the medium access control layer (MAC for wireless local area network. These wireless local area networks use Carrier Sense multiple access with collision avoidance (CSMA/CS for the MAC layer .But only the MAC layer for transmitter is considered here for simulation. So, the Wi-Fi transmitter module is divided into 5 blocks i.e. Data Unit Interface block, Controller block, Pay Load Data Storage, MAC Header Register block and Data Processing block. In this paper we consider only the simulation of MAC header register blocks. So, other blocks i.e. Data unit interface block, Controller block, pay load Data Storage block & Data Processing block are not discussed further in this paper. A field programmable gate array (FPGA device has been used as the hardware implementation platform. The proposed MAC-layer hardware is implemented with Xilinx xcv300e Virtex E FPGA

  2. Performance of a Wireless Sensor Network MAC Protocol with a Variable Sleep Interval

    Directory of Open Access Journals (Sweden)

    M.K. Kirubakaran

    2014-02-01

    Full Text Available A MAC protocol specifies how nodes in a sensor network access a shared communication channel. Medium access control protocols for wireless sensor networks are almost always designed to be energy efficient. Desired properties of such MAC protocol are: it should be distributed and contention-free. This study addresses low power MAC protocols utilize energy in efficient manner in wireless sensor networks. We are interested in the trade-off between power consumption and transmission delay, focusing on low traffic in EM-MAC. In EM-MAC, a significant proportion of the nodes may have to stay awake much longer than envisaged. We describe RRMAC protocol (Receiver-Reservation MAC protocol, a new protocol for the Collision avoidance and energy loss due to retransmissions and increase the life span of a wireless sensor networks. This study concludes with the result of simulation studies which indicate that the use of the proposed RRMAC protocol is expected to increase the life time of wireless sensor networks significantly.

  3. HARVESTED ENERGY-ADAPTIVE MAC PROTOCOL FOR ENERGY HARVESTING IOT NETWORKS

    Directory of Open Access Journals (Sweden)

    Hyeong-Kyu Lee

    2015-12-01

    Full Text Available In energy harvesting IoT networks, an energy queue state of an IoT device will change dynamically and the number of IoT devices that transmit data to the IoT AP will vary in a frame. So we need a MAC protocol to adjust the frame length taking the amount of energy of IoT devices into consideration. Since the existing Framed slotted ALOHA (F-ALOHA Medium Access Control (MAC protocol utilizes the fixed frame size, the resource efficiency can be reduced. In this paper, we propose a Harvested Energy-adaptive Medium Access Control (HEMAC protocol where an IoT Access Point (AP allocates slots in accordance with the number of IoT devices that try to transmit data in a frame. The proposed HE-MAC protocol improves the resource efficiency of the F-ALOHA MAC protocol. We show that the resource efficiency of the HE-MAC protocol is superior to those of the F-ALOHA MAC protocol through simulations.

  4. An Analysis on Decentralized Adaptive MAC Protocols for Cognitive Radio Networks

    Institute of Scientific and Technical Information of China (English)

    Munam Ali Shah; Sijing Zhang; Carsten Maple

    2013-01-01

    The scarcity of bandwidth in the radio spectrum has become more vital since the demand for more and more wireless applications has increased.Most of the spectrum bands have been allocated although many studies have shown that these bands are significantly underutilized most of the time.The problem of unavailability of spectrum and inefficiency in its utilization has been smartly addressed by the cognitive radio (CR) technology which is an opportunistic network that senses the environment,observes the network changes,and then uses knowledge gained from the prior interaction with the network to make intelligent decisions by dynamically adapting their transmission characteristics.In this paper,some of the decentralized adaptive medium access control (MAC) protocols for CR networks have been critically analyzed,and a novel adaptive MAC protocol for CR networks,decentralized non-global MAC (DNG-MAC),has been proposed.The results show the DNG-MAC outperforms other CR-MAC protocols in termsof time and energy efficiency.

  5. Metabolome and fecal microbiota in monozygotic twin pairs discordant for weight: a Big Mac challenge.

    Science.gov (United States)

    Bondia-Pons, Isabel; Maukonen, Johanna; Mattila, Ismo; Rissanen, Aila; Saarela, Maria; Kaprio, Jaakko; Hakkarainen, Antti; Lundbom, Jesper; Lundbom, Nina; Hyötyläinen, Tuulia; Pietiläinen, Kirsi H; Orešič, Matej

    2014-09-01

    Postprandial responses to food are complex, involving both genetic and environmental factors. We studied postprandial responses to a Big Mac meal challenge in monozygotic co-twins highly discordant for body weight. This unique design allows assessment of the contribution of obesity, independent of genetic liability. Comprehensive metabolic profiling using 3 analytical platforms was applied to fasting and postprandial serum samples from 16 healthy monozygotic twin pairs discordant for weight (body mass index difference >3 kg/m(2)). Nine concordant monozygotic pairs were examined as control pairs. Fecal samples were analyzed to assess diversity of the major bacterial groups by using 5 different validated bacterial group specific denaturing gradient gel electrophoresis methods. No differences in fecal bacterial diversity were detected when comparing co-twins discordant for weight (ANOVA, Pfasting state, but their levels converged postprandially (paired t tests, FDR q<0.05). We also found that specific bacterial groups were associated with postprandial changes of specific metabolites. Our findings underline important roles of genetic and early life factors in the regulation of postprandial metabolite levels.

  6. A Software-Defined Radio System for Intravehicular Wireless Sensor Networks

    Directory of Open Access Journals (Sweden)

    Xiangming Kong

    2010-01-01

    Full Text Available An intra-vehicular wireless sensor network is designed and implemented on a software-defined radio system. IUWB signal is chosen to carry the data packets. The MAC layer of the system follows the specification of the IEEE802.15.4 standard. The transceiver design, especially the receiver design, is detailed in the paper. The system design is validated through lab test setup.

  7. Association between gross motor function (GMFCS and manual ability (MACS in children with cerebral palsy. A population-based study of 359 children

    Directory of Open Access Journals (Sweden)

    Arner Marianne

    2007-06-01

    Full Text Available Abstract Background The Gross Motor Function Classification System (GMFCS has become an important tool to describe motor function in children with Cerebral Palsy (CP. The Manual Ability Classification System (MACS was developed recently as a corresponding classification of manual ability. The aim of this study was to describe the association between gross motor function and manual ability in a total population of children with cerebral palsy. Methods 365 children, born 1992 to 2001, who were registered in a population-based health care programme (CPUP for children with CP living in the south of Sweden were included in the study. GMFCS was evaluated by the child's physiotherapist and MACS by the occupational therapist. CP diagnosis and subtype were determined by the neuropaediatrician at or after the age of four. Results GMFCS levels were available in all 365 children, MACS levels in 359 (98%. There was a poor overall correlation between gross motor function and manual ability. However, different associations between gross motor function and manual ability were found in the different diagnostic subtypes. Children with spastic hemiplegia generally had a lower level of manual ability than gross motor function (p Conclusion Gross motor function and manual ability are often discrepant in children with CP, and the patterns seem to vary across the different subgroups based on the predominant neurological findings. To give a complete clinical picture when evaluating these children, both aspects have to be described. The GMFCS and the MACS seem to work well in this context and seem very useful in population-based studies, in health care registers for children with CP, and in clinical practice.

  8. Defining the fascial system.

    Science.gov (United States)

    Adstrum, Sue; Hedley, Gil; Schleip, Robert; Stecco, Carla; Yucesoy, Can A

    2017-01-01

    Fascia is a widely used yet indistinctly defined anatomical term that is concurrently applied to the description of soft collagenous connective tissue, distinct sections of membranous tissue, and a body pervading soft connective tissue system. Inconsistent use of this term is causing concern due to its potential to confuse technical communication about fascia in global, multiple discipline- and multiple profession-spanning discourse environments. The Fascia Research Society acted to address this issue by establishing a Fascia Nomenclature Committee (FNC) whose purpose was to clarify the terminology relating to fascia. This committee has since developed and defined the terms a fascia, and, more recently, the fascial system. This article reports on the FNC's proposed definition of the fascial system. Copyright © 2016 Elsevier Ltd. All rights reserved.

  9. Defining Legal Moralism

    DEFF Research Database (Denmark)

    Thaysen, Jens Damgaard

    2015-01-01

    This paper discusses how legal moralism should be defined. It is argued that legal moralism should be defined as the position that “For any X, it is always a pro tanto reason for justifiably imposing legal regulation on X that X is morally wrong (where “morally wrong” is not conceptually equivalent...... to “harmful”)”. Furthermore, a distinction between six types of legal moralism is made. The six types are grouped according to whether they are concerned with the enforcement of positive or critical morality, and whether they are concerned with criminalising, legally restricting, or refraining from legally...... protecting morally wrong behaviour. This is interesting because not all types of legal moralism are equally vulnerable to the different critiques of legal moralism that have been put forth. Indeed, I show that some interesting types of legal moralism have not been criticised at all....

  10. Define Digital Vernacular

    Institute of Scientific and Technical Information of China (English)

    刘佳; 李海英; James Stevens; Rough Nelson

    2014-01-01

    As science and technology developed, the tools of humans developed from humans’hands, to mechanical and digital technologies. The tools influ-ence almost everything in the humans’world, so does vernacular. The digital vernacular could be understood as using digital technology to vernacular; the digital means technologies. It also could be understood as doing vernacular in a digital way;the digital means data and information, in other words it can be seeking truth from facts. Define digital vernacular is not only what is digital vernacular, but also about how to do the digital vernacular and what kind of attitude we should hold to-ward the digital vernacular. Define digital vernacular as both thinking and doing.

  11. Defining local food

    DEFF Research Database (Denmark)

    Eriksen, Safania Normann

    2013-01-01

    Despite evolving local food research, there is no consistent definition of “local food.” Various understandings are utilized, which have resulted in a diverse landscape of meaning. The main purpose of this paper is to examine how researchers within the local food systems literature define local...... food, and how these definitions can be used as a starting point to identify a new taxonomy of local food based on three domains of proximity....

  12. [To define internet addiction].

    Science.gov (United States)

    Tonioni, Federico

    2013-01-01

    Internet addiction is a new behavioral disorder difficult to define, especially when referring to young teenagers who make great use of web-mediated relationships. It's necessary to separate the cases of overt dependency on those in which the abuse of internet seems to have a different value, offering the only way to achieve the possible relationship. Internet is mediating a new way of communicating and thinking, this may favor the onset of clinical phenomena intended to surprise.

  13. Decidability of definability

    CERN Document Server

    Tsankov, Manuel Bodirsky; Michael Pinsker; Todor

    2010-01-01

    For a fixed infinite structure $\\Gamma$ with finite signature $\\tau$, we study the following computational problem: Input are quantifier-free first-order $\\tau$-formulas $\\phi_0,\\phi_1,\\dots,\\phi_n$ that define relations $R_0,R_1,\\dots,R_n$ over $\\Gamma$. The question is whether the relation $R_0$ is primitive positive definable from $R_1,\\ldots,R_n$, i.e., definable by a first-order formula that uses only relation symbols for $R_1, \\dots, R_n$, equality, conjunctions, and existential quantification (disjunction, negation, and universal quantification are forbidden). We show decidability of this problem for all structures $\\Gamma$ that have a first-order definition in an ordered homogeneous structure $\\Delta$ with a finite language whose age is a Ramsey class and determined by finitely many forbidden substructures. Examples for structures $\\Gamma$ with this property are the order of the rationals, the random graph, the homogeneous universal poset, the random tournament, all homogeneous universal $C$-relations...

  14. Long-lived high and intermediate level radioactive wastes: defining the context, stakes and perspectives; Dechets radioactifs de haute activite et de moyenne activite a vie longue: situer le contexte, les enjeux et les perspectives

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2006-07-01

    The French law from December 30, 1991 has defined an ambitious 15 years program of researches in order to explore the different possible paths for the long-term management of long-lived high and intermediate level radioactive wastes. The law foresees also that at the end of the 15 years research program, a project of law will be prepared by the French government and transmitted to the European parliament in 2006. A public debate has been organized and emceed in 2005 in order dialogue with the general public and to gather its questions, remarks and fears. In the framework of their contribution to this debate, the ministries of industry and environment have prepared this document which answers some key questions about radioactive waste management: where do wastes come from, what are the risks, how are they managed today in France and in foreign countries, what are the results of the researches carried out during 15 years, what are the advantages and drawbacks of each waste management solution considered, what is the perspective of application of each solution, what is the position of experts, what will be the decision process. This synthetic document supplies some reference marks to better understand these different points. Some pedagogical files about radioactivity, fuel cycle, and nuclear industry activities are attached to the document. (J.S.)

  15. Can a Gleason 6 or Less Microfocus of Prostate Cancer in One Biopsy and Prostate-Specific Antigen Level <10 ng/mL Be Defined as the Archetype of Low-Risk Prostate Disease?

    Directory of Open Access Journals (Sweden)

    Gianluigi Taverna

    2012-01-01

    Full Text Available Prostate cancer (PC remains a cause of death worldwide. Here we investigate whether a single microfocus of PC at the biopsy (graded as Gleason 6 or less, ≤5% occupancy and the PSA <10 ng/mL can define the archetype of low-risk prostate disease. 4500 consecutive patients were enrolled. Among them, 134 patients with a single micro-focus of PC were followed up, and the parameters influencing the biochemical relapse (BR were analysed. Out of 134 patients, 94 had clinically significant disease, specifically in 74.26% of the patients with PSA <10 ng/mL. Positive surgical margins and the extracapsular invasion were found in 29.1% and 51.4% patients, respectively. BR was observed in 29.6% of the patients. Cox regression evidenced a correlation between the BR and Gleason grade at the retropubic radical prostatectomy (RRP, capsular invasion, and the presence of positive surgical margins. Multivariate regression analysis showed a statistically significant correlation between the presence of surgical margins at the RRP and BR. Considering a single micro-focus of PC at the biopsy and PSA serum level <10 ng/mL, clinically significant disease was found in 74.26% patients and only positive surgical margins are useful for predicting the BR.

  16. Use of MAC-ELISA for evaluation of yellow fever vaccination Uso do MAC-ELISA para avaliação de vacinados contra febre amarela

    Directory of Open Access Journals (Sweden)

    Rita M. Ribeiro Nogueira

    1992-10-01

    Full Text Available An evaluation of the IgM antibody immune response against yellow fever using strain 17D was carried out by MAC-ELISA and PRNT. The results showed an agreement of 97% between both tests and the authors conclude that MAC-ELISA can be used as a specific and sensitive asssay to replace the PRNT for detecting yellow fever antibodies in human sera, after vaccination programs.Foi avaliada a resposta imune de anticorpos IgM em vacinados contra febre amarela usando a amostra 17D empregando-se provas de captura de anticorpos IgM (MAC-ELISA e teste de neutralização por redução de placas (PRNT. Os resulta-dos mostraram uma concordância de 97% entre ambas as provas e os autores concluem que o MAC-ELISA pode ser utilizado como um método específico e sensível para substituir o teste de neutralização para detecção de anticorpos IgM em vacinados contra febre amarela.

  17. Intracluster light properties in the CLASH-VLT cluster MACS J1206.2-0847

    Science.gov (United States)

    Presotto, V.; Girardi, M.; Nonino, M.; Mercurio, A.; Grillo, C.; Rosati, P.; Biviano, A.; Annunziatella, M.; Balestra, I.; Cui, W.; Sartoris, B.; Lemze, D.; Ascaso, B.; Moustakas, J.; Ford, H.; Fritz, A.; Czoske, O.; Ettori, S.; Kuchner, U.; Lombardi, M.; Maier, C.; Medezinski, E.; Molino, A.; Scodeggio, M.; Strazzullo, V.; Tozzi, P.; Ziegler, B.; Bartelmann, M.; Benitez, N.; Bradley, L.; Brescia, M.; Broadhurst, T.; Coe, D.; Donahue, M.; Gobat, R.; Graves, G.; Kelson, D.; Koekemoer, A.; Melchior, P.; Meneghetti, M.; Merten, J.; Moustakas, L. A.; Munari, E.; Postman, M.; Regős, E.; Seitz, S.; Umetsu, K.; Zheng, W.; Zitrin, A.

    2014-05-01

    Aims: We aim constrain the assembly history of clusters by studying the intracluster light (ICL) properties, estimating its contribution to the fraction of baryons in stars, f∗, and understanding possible systematics or bias using different ICL detection techniques. Methods: We developed an automated method, GALtoICL, based on the software GALAPAGOS, to obtain a refined version of typical BCG+ICL maps. We applied this method to our test case MACS J1206.2-0847, a massive cluster located at z ~ 0.44, which is part of the CLASH sample. Using deep multiband Subaru images, we extracted the surface brightness (SB) profile of the BCG+ICL and studied the ICL morphology, color, and contribution to f∗ out to R500. We repeated the same analysis using a different definition of the ICL, SBlimit method, i.e., a SB cut-off level, to compare the results. Results: The most peculiar feature of the ICL in MACS1206 is its asymmetric radial distribution, with an excess in the SE direction and extending toward the second brightest cluster galaxy, which is a post starburst galaxy. This suggests an interaction between the BCG and this galaxy that dates back to τ ≤ 1.5 Gyr. The BCG+ICL stellar content is ~8% of M∗,500, and the (de-) projected baryon fraction in stars is f∗ = 0.0177(0.0116), in excellent agreement with recent results. The SBlimit method provides systematically higher ICL fractions and this effect is stronger at lower SB limits. This is due to the light from the outer envelopes of member galaxies that contaminate the ICL. Though more time consuming, the GALtoICL method provides safer ICL detections that are almost free of this contamination. This is one of the few ICL study at redshift z > 0.3. At completion, the CLASH/VLT program will allow us to extend this analysis to a statistically significant cluster sample spanning a wide redshift range: 0.2 ≲ z ≲ 0.6. Based on data collected at the NASJ Subaru telescope, at the ESO VLT (prog.ID 186.A-0798), and the

  18. Defining Z in Q

    CERN Document Server

    Koenigsmann, Jochen

    2010-01-01

    We show that ${\\mathbb Z}$ is definable in ${\\mathbb Q}$ by a universal first-order formula in the language of rings. We also present an $\\forall\\exists$-formula for ${\\mathbb Z}$ in ${\\mathbb Q}$ with just one universal quantifier. We exhibit new diophantine subsets of ${\\mathbb Q}$ like the set of non-squares or the complement of the image of the norm map under a quadratic extension. Finally, we show that there is no existential formula for ${\\mathbb Z}$ in ${\\mathbb Q}$, provided one assumes a strong variant of the Bombieri-Lang Conjecture for varieties over ${\\mathbb Q}$ with many ${\\mathbb Q}$-rational points.

  19. Precise strong lensing mass profile of the CLASH galaxy cluster MACS 2129

    CERN Document Server

    Monna, A; Balestra, I; Rosati, P; Grillo, C; Halkola, A; Suyu, S H; Coe, D; Frye, B; Koekemoer, A; Mercurio, A; Postman, M

    2016-01-01

    We present a detailed strong lensing mass reconstruction of the core of the galaxy cluster MACSJ 2129.4-0741 ($\\rm z_{cl}=0.589$) obtained by combining high-resolution HST photometry from the CLASH survey with new spectroscopic observations from the CLASH-VLT survey. A background bright red passive galaxy at $\\rm z_{sp}=1.36$, sextuply lensed in the cluster core, has four radial lensed images located over the three central cluster members. Further 19 background lensed galaxies are spectroscopically confirmed by our VLT survey, including 3 additional multiple systems. A total of 27 multiple images are used in the lensing analysis. This allows us to trace with high precision the total mass profile of the cluster in its very inner region ($\\rm R<100$ kpc). Our final lensing mass model reproduces the multiple images systems identified in the cluster core with high accuracy of $0.4''$. This translates in an high precision mass reconstruction of MACS 2129, which is constrained at level of 3%. The cluster has Ein...

  20. Characterization of the murine myeloid precursor cell line MuMac-E8.

    Science.gov (United States)

    Fricke, Stephan; Pfefferkorn, Cathleen; Wolf, Doris; Riemschneider, Sina; Kohlschmidt, Janine; Hilger, Nadja; Fueldner, Christiane; Knauer, Jens; Sack, Ulrich; Emmrich, Frank; Lehmann, Jörg

    2014-01-01

    Starting point for the present work was the assumption that the cell line MuMac-E8 represents a murine cell population with stem cell properties. Preliminary studies already pointed to the expression of stem-cell associated markers and a self-regenerative potential of the cells. The cell line MuMac-E8 should be examined for their differential stage within stem cell hierarchy. MuMac-E8 cells were derived from a chimeric mouse model of arthritis. It could be shown that MuMac-E8 cells express mRNA of some genes associated with pluripotent stem cells (Nanog, Nucleostemin), of genes for hematopoietic markers (EPCR, Sca-1, CD11b, CD45), for the mesenchymal marker CD105 and of genes for the neural markers Pax-6 and Ezrin. In methylcellulose and May-Grünwald-Giemsa staining, hematopoietic colonies were obtained but the hematopoietic system of lethally irradiated mice could not be rescued. Osteogenic differentiation was not detectable. Thus, it became evident that MuMac-E8 represents not a stem cell line. However, MuMac-E8 cells expressed several myeloid surface markers (i.e. CD11b, F4/80, CD14, CD64), showed phagocytosis and is capable of producing nitric oxide. Thus, this cell line seems to be arrested an advanced stage of myeloid differentiation. Adherence data measured by impedance-based real-time cell analysis together with cell morphology data suggested that MuMac-E8 represents a new macrophage precursor cell line exhibiting weak adherence. This cell line is suitable as an in-vitro model for testing of macrophage functions. Moreover, it might be also useful for differentiation or reprogramming studies.

  1. Characterization of the murine myeloid precursor cell line MuMac-E8.

    Directory of Open Access Journals (Sweden)

    Stephan Fricke

    Full Text Available Starting point for the present work was the assumption that the cell line MuMac-E8 represents a murine cell population with stem cell properties. Preliminary studies already pointed to the expression of stem-cell associated markers and a self-regenerative potential of the cells. The cell line MuMac-E8 should be examined for their differential stage within stem cell hierarchy. MuMac-E8 cells were derived from a chimeric mouse model of arthritis. It could be shown that MuMac-E8 cells express mRNA of some genes associated with pluripotent stem cells (Nanog, Nucleostemin, of genes for hematopoietic markers (EPCR, Sca-1, CD11b, CD45, for the mesenchymal marker CD105 and of genes for the neural markers Pax-6 and Ezrin. In methylcellulose and May-Grünwald-Giemsa staining, hematopoietic colonies were obtained but the hematopoietic system of lethally irradiated mice could not be rescued. Osteogenic differentiation was not detectable. Thus, it became evident that MuMac-E8 represents not a stem cell line. However, MuMac-E8 cells expressed several myeloid surface markers (i.e. CD11b, F4/80, CD14, CD64, showed phagocytosis and is capable of producing nitric oxide. Thus, this cell line seems to be arrested an advanced stage of myeloid differentiation. Adherence data measured by impedance-based real-time cell analysis together with cell morphology data suggested that MuMac-E8 represents a new macrophage precursor cell line exhibiting weak adherence. This cell line is suitable as an in-vitro model for testing of macrophage functions. Moreover, it might be also useful for differentiation or reprogramming studies.

  2. Software-Defined Cluster

    Institute of Scientific and Technical Information of China (English)

    聂华; 杨晓君; 刘淘英

    2015-01-01

    The cluster architecture has played an important role in high-end computing for the past 20 years. With the advent of Internet services, big data, and cloud computing, traditional clusters face three challenges: 1) providing flexible system balance among computing, memory, and I/O capabilities;2) reducing resource pooling overheads;and 3) addressing low performance-power efficiency. This position paper proposes a software-defined cluster (SDC) architecture to deal with these challenges. The SDC architecture inherits two features of traditional cluster: its architecture is multicomputer and it has loosely-coupled interconnect. SDC provides two new mechanisms: global I/O space (GIO) and hardware-supported native access (HNA) to remote devices. Application software can define a virtual cluster best suited to its needs from resources pools provided by a physical cluster, and traditional cluster ecosystems need no modification. We also discuss a prototype design and implementation of a 32-processor cloud server utilizing the SDC architecture.

  3. An energy-efficient MAC protocol using dynamic queue management for delay-tolerant mobile sensor networks.

    Science.gov (United States)

    Li, Jie; Li, Qiyue; Qu, Yugui; Zhao, Baohua

    2011-01-01

    Conventional MAC protocols for wireless sensor network perform poorly when faced with a delay-tolerant mobile network environment. Characterized by a highly dynamic and sparse topology, poor network connectivity as well as data delay-tolerance, delay-tolerant mobile sensor networks exacerbate the severe power constraints and memory limitations of nodes. This paper proposes an energy-efficient MAC protocol using dynamic queue management (EQ-MAC) for power saving and data queue management. Via data transfers initiated by the target sink and the use of a dynamic queue management strategy based on priority, EQ-MAC effectively avoids untargeted transfers, increases the chance of successful data transmission, and makes useful data reach the target terminal in a timely manner. Experimental results show that EQ-MAC has high energy efficiency in comparison with a conventional MAC protocol. It also achieves a 46% decrease in packet drop probability, 79% increase in system throughput, and 25% decrease in mean packet delay.

  4. 42 CFR 405.1104 - Request for MAC review when an ALJ does not issue a decision timely.

    Science.gov (United States)

    2010-10-01

    ... 42 Public Health 2 2010-10-01 2010-10-01 false Request for MAC review when an ALJ does not issue a...) Medicare Appeals Council Review § 405.1104 Request for MAC review when an ALJ does not issue a decision... under § 405.1016 may request MAC review if— (1) The appellant files a written request with the ALJ to...

  5. Implementing Software Defined Radio

    CERN Document Server

    Grayver, Eugene

    2013-01-01

    Software Defined Radio makes wireless communications easier, more efficient, and more reliable. This book bridges the gap between academic research and practical implementation. When beginning a project, practicing engineers, technical managers, and graduate students can save countless hours by considering the concepts presented in these pages. The author covers the myriad options and trade-offs available when selecting an appropriate hardware architecture. As demonstrated here, the choice between hardware- and software-centric architecture can mean the difference between meeting an aggressive schedule and bogging down in endless design iterations. Because of the author’s experience overseeing dozens of failed and successful developments, he is able to present many real-life examples. Some of the key concepts covered are: Choosing the right architecture for the market – laboratory, military, or commercial Hardware platforms – FPGAs, GPPs, specialized and hybrid devices Standardization efforts to ens...

  6. Defining cyber warfare

    Directory of Open Access Journals (Sweden)

    Dragan D. Mladenović

    2012-04-01

    Full Text Available Cyber conflicts represent a new kind of warfare that is technologically developing very rapidly. Such development results in more frequent and more intensive cyber attacks undertaken by states against adversary targets, with a wide range of diverse operations, from information operations to physical destruction of targets. Nevertheless, cyber warfare is waged through the application of the same means, techniques and methods as those used in cyber criminal, terrorism and intelligence activities. Moreover, it has a very specific nature that enables states to covertly initiate attacks against their adversaries. The starting point in defining doctrines, procedures and standards in the area of cyber warfare is determining its true nature. In this paper, a contribution to this effort was made through the analysis of the existing state doctrines and international practice in the area of cyber warfare towards the determination of its nationally acceptable definition.

  7. Eliminating the Heart from the Curcumin Molecule: Monocarbonyl Curcumin Mimics (MACs

    Directory of Open Access Journals (Sweden)

    Dinesh Shetty

    2014-12-01

    Full Text Available Curcumin is a natural product with several thousand years of heritage. Its traditional Asian application to human ailments has been subjected in recent decades to worldwide pharmacological, biochemical and clinical investigations. Curcumin’s Achilles heel lies in its poor aqueous solubility and rapid degradation at pH ~ 7.4. Researchers have sought to unlock curcumin’s assets by chemical manipulation. One class of molecules under scrutiny are the monocarbonyl analogs of curcumin (MACs. A thousand plus such agents have been created and tested primarily against cancer and inflammation. The outcome is clear. In vitro, MACs furnish a 10–20 fold potency gain vs. curcumin for numerous cancer cell lines and cellular proteins. Similarly, MACs have successfully demonstrated better pharmacokinetic (PK profiles in mice and greater tumor regression in cancer xenografts in vivo than curcumin. The compounds reveal limited toxicity as measured by murine weight gain and histopathological assessment. To our knowledge, MAC members have not yet been monitored in larger animals or humans. However, Phase 1 clinical trials are certainly on the horizon. The present review focuses on the large and evolving body of work in cancer and inflammation, but also covers MAC structural diversity and early discovery for treatment of bacteria, tuberculosis, Alzheimer’s disease and malaria.

  8. Cooperative Defense Against Pollution Attacks in Network Coding Using SpaceMac

    CERN Document Server

    Le, Anh

    2011-01-01

    Intra-session network coding is known to be vulnerable to pollution attacks. In this work, first, we introduce a novel homomorphic MAC scheme called SpaceMac, which allows an intermediate node to verify if its received packets belong to a specific subspace, even if the subspace is expanding over time. Then, we use SpaceMac as a building block to design a cooperative scheme that provides complete defense against pollution attacks: (i) it can detect polluted packets early at intermediate nodes and (ii) it can identify the exact location of all, even colluding, attackers, thus making it possible to eliminate them. Our scheme is cooperative: parents and children of any node cooperate to detect any corrupted packets sent by the node, and nodes in the network cooperate with a central controller to identify the exact location of all attackers. We implement SpaceMac in both C/C++ and Java as a library, and we make the library available online. Our evaluation on both a PC and an Android device shows that (i) SpaceMac'...

  9. Silicon Nanostructures Produced by Modified MacEtch Method for Antireflective Si Surface.

    Science.gov (United States)

    Nichkalo, Stepan; Druzhinin, Anatoly; Evtukh, Anatoliy; Bratus', Oleg; Steblova, Olga

    2017-12-01

    This work pertains to the method for modification of silicon (Si) wafer morphology by metal-assisted chemical etching (MacEtch) technique suitable for fabrication of antireflective Si surfaces. For this purpose, we made different Au catalyst patterns on the surface of Si substrate. This modification allowed to obtain the close-packed Au nanodrop (ND) pattern that generates the nanowires (NWs) and the well-separated Au NDs, which induce the nanopore (NP) formation. The antireflective properties of these structures in comparison with NWs produced by the conventional Ag-MacEtch method were analysed. The total surface reflectance of 1~7% for SiNWs and ~17% for SiNPs was observed over the entire Si-absorbing region. Moreover, SiNWs prepared by Au-MacEtch demonstrate better antireflective properties in contrast to those formed by conventional Ag-assisted chemical etching. So, the use of SiNWs produced by the modified Au-MacEtch method as the antireflective material is favored over those prepared by Ag-MacEtch due to their higher light absorption and lower reflectance. The possible reason of these findings is discussed.

  10. A macrophage activation switch (MAcS)-index for assessment of monocyte/macrophage activation

    DEFF Research Database (Denmark)

    Maniecki, Maciej Bogdan; Lauridsen, Mette; Knudsen, Troels Bygum

    2008-01-01

    of inflammatory markers (IL-1β, IL-6, IL-8, IL-10, and TNF-α) was determined by RT-qPCR. Normalized values of sCD163 and mCD163 were calculated by dividing each value by the median value of the healthy population. The MAcS-index was then calculated as the ratio between normalized sCD163 and normalized mCD163....... A MAcS-index > 1 indicates relative increase in sCD163 as compared to mCD163, suggested to reflect a predominant M1 activation.   RESULTS AND DISCUSSION: The MAcS-index of healthy individuals clustered around 1 (2.5-97.5 percentile: 0.28-3.11), whereas the MAcS-index of the patients varied from 0.......06 to 5139, with 4% below the 2.5 % limit of healthy individuals, and 60% above the 97.5 upper limit of healthy individuals.  The MAcS-index in infected patients (with assumed M1 activation) was clearly elevated. The index was significantly higher in patients with clinical signs of infection (median: 9...

  11. MAP, MAC, and vortex-rings configurations in the Weinberg-Salam model

    Science.gov (United States)

    Teh, Rosy; Ng, Ban-Loong; Wong, Khai-Ming

    2015-11-01

    We report on the presence of new axially symmetric monopoles, antimonopoles and vortex-rings solutions of the SU(2)×U(1) Weinberg-Salam model of electromagnetic and weak interactions. When the ϕ-winding number n = 1, and 2, the configurations are monopole-antimonopole pair (MAP) and monopole-antimonopole chain (MAC) with poles of alternating sign magnetic charge arranged along the z-axis. Vortex-rings start to appear from the MAP and MAC configurations when the winding number n = 3. The MAP configurations possess zero net magnetic charge whereas the MAC configurations possess net magnetic charge of 4 πn / e. In the MAP configurations, the monopole-antimonopole pair is bounded by the Z0 field flux string and there is an electromagnetic current loop encircling it. The monopole and antimonopole possess magnetic charges ± 4πn/e sin2θW respectively. In the MAC configurations there is no string connecting the monopole and the adjacent antimonopole and they possess magnetic charges ± 4 πn/e respectively. The MAC configurations possess infinite total energy and zero magnetic dipole moment whereas the MAP configurations which are actually sphalerons possess finite total energy and magnetic dipole moment. The configurations were investigated for varying values of Higgs self-coupling constant 0 ≤ λ ≤ 40 at Weinberg angle θW = π/4.

  12. Assessing the Accuracy of High Resolution Digital Surface Models Computed by PhotoScan® and MicMac® in Sub-Optimal Survey Conditions

    Directory of Open Access Journals (Sweden)

    Marion Jaud

    2016-06-01

    Full Text Available For monitoring purposes and in the context of geomorphological research, Unmanned Aerial Vehicles (UAV appear to be a promising solution to provide multi-temporal Digital Surface Models (DSMs and orthophotographs. There are a variety of photogrammetric software tools available for UAV-based data. The objective of this study is to investigate the level of accuracy that can be achieved using two of these software tools: Agisoft PhotoScan® Pro and an open-source alternative, IGN© MicMac®, in sub-optimal survey conditions (rugged terrain, with a large variety of morphological features covering a range of roughness sizes, poor GPS reception. A set of UAV images has been taken by a hexacopter drone above the Rivière des Remparts, a river on Reunion Island. This site was chosen for its challenging survey conditions: the topography of the study area (i involved constraints on the flight plan; (ii implied errors on some GPS measurements; (iii prevented an optimal distribution of the Ground Control Points (GCPs and; (iv was very complex to reconstruct. Several image processing tests are performed with different scenarios in order to analyze the sensitivity of each software package to different parameters (image quality, numbers of GCPs, etc.. When computing the horizontal and vertical errors within a control region on a set of ground reference targets, both methods provide rather similar results. A precision up to 3–4 cm is achievable with these software packages. The DSM quality is also assessed over the entire study area comparing PhotoScan DSM and MicMac DSM with a Terrestrial Laser Scanner (TLS point cloud. PhotoScan and MicMac DSM are also compared at the scale of particular features. Both software packages provide satisfying results: PhotoScan is more straightforward to use but its source code is not open; MicMac is recommended for experimented users as it is more flexible.

  13. A network architecture for precision formation flying using the IEEE 802.11 MAC Protocol

    Science.gov (United States)

    Clare, Loren P.; Gao, Jay L.; Jennings, Esther H.; Okino, Clayton

    2005-01-01

    Precision Formation Flying missions involve the tracking and maintenance of spacecraft in a desired geometric formation. The strong coupling of spacecraft in formation flying control requires inter-spacecraft communication to exchange information. In this paper, we present a network architecture that supports PFF control, from the initial random deployment phase to the final formation. We show that a suitable MAC layer for the application protocol is IEEE's 802.11 MAC protocol. IEEE 802.11 MAC has two modes of operations: DCF and PCF. We show that DCF is suitable for the initial deployment phase while switching to PCF when the spacecraft are in formation improves jitter and throughput. We also consider the effect of routing on protocol performance and suggest when it is profitable to turn off route discovery to achieve better network performance.

  14. MAC-layer protocol for TCP fairness in Wireless Mesh Networks

    KAUST Repository

    Nawab, Faisal

    2012-08-01

    In this paper we study the interactions of TCP and IEEE 802.11 MAC in Wireless Mesh Networks (WMNs). We use a Markov chain to capture the behavior of TCP sessions, particularly the impact on network throughput performance due to the effect of queue utilization and packet relaying. A closed form solution is derived to numerically determine the throughput. Based on the developed model, we propose a distributed MAC protocol to alleviate the unfairness problem in WMNs. Our protocol uses the age of packet as a priority metric for packet scheduling. Simulation is conducted to validate our model and to illustrate the fairness characteristics of our proposed MAC protocol. We conclude that we can achieve fairness with only little impact on network capacity.

  15. RMAC: A Reliable MAC Protocol Supporting Multicast for Wireless Ad Hoc Networks

    Institute of Scientific and Technical Information of China (English)

    Wei-Sheng Si; Cheng-Zhi Li

    2005-01-01

    This paper presents a new reliable MAC protocol called "RMAC" supporting reliable multicast for wireless ad hoc networks. By utilizing the busy tones to realize the multicast reliability, RMAC has three novelties: (1) it uses a variablelength control frame to stipulate an order for the receivers to respond, thus solving the feedback collision problem; (2) it extends the usage of busy tone for preventing data frame collisions into the multicast scenario; and (3) it introduces a new usage of busy tone for acknowledging data frames positively. In addition, RMAC is generalized into a comprehensive MAC protocol that provides both reliable and unreliable services for all the three modes of communications: unicast, multicast,and broadcast, making it capable of supporting various upper-layer protocols. The evaluation shows that RMAC achieves high reliability with very limited overhead. RMAC is also compared with other reliable MAC protocols, showing that RMAC not only provides higher reliability but also involves lower cost.

  16. The international epidemiology of disseminated Mycobacterium avium complex infection in AIDS. International MAC Study Group.

    Science.gov (United States)

    Fordham von Reyn, C; Arbeit, R D; Tosteson, A N; Ristola, M A; Barber, T W; Waddell, R; Sox, C H; Brindle, R J; Gilks, C F; Ranki, A; Bartholomew, C; Edwards, J; Falkinham, J O; O'Connor, G T

    1996-08-01

    To determine rates of disseminated Mycobacterium avium complex (MAC) infection among AIDS patients in developed and developing countries, and to determine whether different rates reflect differences in exposure or immunity, or both. Prospective cohort study. University hospitals and outpatient AIDS programs. HIV-infected subjects with CD4 counts or = 5 mm were present in 20% of patients from Kenya compared to 1% at other sites (P swimming in an indoor pool, history of bronchoscopy, regular consumption of raw or partially cooked fish/shellfish and treatment with granulocyte colony-stimulating factor. Rates of disseminated MAC in AIDS are higher in developed than developing countries and are due to both differences in exposure and differences in immunity. These data provide a rationale for prevention of MAC through both active immunization and reduction in exposure to the organism.

  17. Performance evaluation of IEEE 802.11 MAC layer in supporting delay sensitive services

    Directory of Open Access Journals (Sweden)

    Jyotsna Sengupta

    2010-02-01

    Full Text Available Providing QoS requirements like good throughput and minimum access delay are challenging tasks with regard to 802.11 WLAN protocols and Medium Access Control (MAC functions. IEEE 802.11 MAC layer supports two main protocols: DCF (Distributed Coordination Function and EDCF (Enhanced Distributed Coordination Function. During the evaluation of EDCF, the performance of various access categories was thedetermining factor. Two scenarios, with same Physical and MAC parameters, one implementing the DCF and other EDCF, were created in the network simulation tool (OPNET MODELER [5] to obtain the results. The results showed that the performance of EDCF was better in providing QoS for real-time interactive services (like video conferencing as compared to DCF, because of its ability to differentiate and prioritize various services. Whereas the DCF’s overall performance was marginally better for all kinds of services taken together.

  18. A MAC protocol for medical monitoring applications of wireless body area networks.

    Science.gov (United States)

    Shu, Minglei; Yuan, Dongfeng; Zhang, Chongqing; Wang, Yinglong; Chen, Changfang

    2015-06-03

    Targeting the medical monitoring applications of wireless body area networks (WBANs), a hybrid medium access control protocol using an interrupt mechanism (I-MAC) is proposed to improve the energy and time slot utilization efficiency and to meet the data delivery delay requirement at the same time. Unlike existing hybrid MAC protocols, a superframe structure with a longer length is adopted to avoid unnecessary beacons. The time slots are mostly allocated to nodes with periodic data sources. Short interruption slots are inserted into the superframe to convey the urgent data and to guarantee the real-time requirements of these data. During these interruption slots, the coordinator can break the running superframe and start a new superframe. A contention access period (CAP) is only activated when there are more data that need to be delivered. Experimental results show the effectiveness of the proposed MAC protocol in WBANs with low urgent traffic.

  19. An Approach to Analyze Physical Memory Image File of Mac OS X

    Institute of Scientific and Technical Information of China (English)

    LiJuan Xu; LianHai Wang

    2014-01-01

    Memory analysis is one of the key techniques in computer live forensics. Especially, the analysis of a Mac OS X operating system’ s memory image file plays an important role in identifying the running status of an apple computer. However, how to analyze the image file without using extra”mach-kernel” file is one of the unsolved difficulties. In this paper, we firstly compare several approaches for physical memory acquisition and analyze the effects of each approach on physical memory. Then, we discuss the traditional methods for the physical memory file analysis of Mac OS X. A novel physical memory image file analysis approach without using extra“mach-kernel” file is proposed base on the discussion. We verify the performance of the new approach on Mac OS X 10�8�2. The experimental results show that the proposed approach is simpler and more practical than previous ones.

  20. Optimization of listening time of S-MAC for wireless sensor networks

    Institute of Scientific and Technical Information of China (English)

    LI Cheng; WANG Kui-ru; ZHANG Jin-long; ZHAO De-xin; LI Wang

    2009-01-01

    In wireless sensor networks, sensor nodes are usually battery-operated computing and sensing devices, hence operations are limited by the initially equipped batteries, which are hard to be recharged or replaced. In this sense, saving energy consumption becomes significant. As most energy waste is from the always-on wireless interface, S-MAC is suggested to reduce energy consumption by introducing periodic listen/sleep scheme. However, when designing the listening time, S-MAC fails to consider the traffic distribution factor. In this article, an optimization for this scheme is proposed based on the distribution model. Evaluations show that the optimized S-MAC achieves considerable improvement in energy and latency.