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Sample records for ma chung pj

  1. Ma

    Directory of Open Access Journals (Sweden)

    Ingrid Berthon-Moine

    2012-01-01

    Full Text Available Ma (2009 is a single channel video of a mother and child walking together side by side, holding hands. The title is reminiscent of the affectionate nickname for a mother, 'Ma', but also a concealed way to convey maternal ambivalence. Maternal ambivalence is the result of the tension between the idealisation of motherhood and women’s lived experience of mothering. The maternal struggle finds its source in the difficulty of identifying with the ideological representation of the mother. This image still conveys an idealistic and nostalgic, patriarchal image of maternal love bounded by culture and history. http://podcast.ulcc.ac.uk/accounts/BirkbeckCollege/mamsie/MA.mov

  2. Evaluation of multifrequency range imaging technique implemented on the Chung-Li VHF atmospheric radar

    Science.gov (United States)

    Chen, Jenn-Shyong; Tsai, Shih-Chiao; Su, Ching-Lun; Chu, Yen-Hsyang

    2016-05-01

    The multifrequency range imaging technique (RIM) has been implemented on the Chung-Li VHF array radar since 2008 after its renovation. This study made a more complete examination and evaluation of the RIM technique to facilitate the performance of the radar for atmospheric studies. RIM experiments with various radar parameters such as pulse length, pulse shape, receiver bandwidth, transmitter frequency set, and so on were conducted. The radar data employed for the study were collected from 2008 to 2013. It has been shown that two factors, the range/time delay of the signal traveling in the media and the standard deviation of Gaussian-shaped range-weighting function, play crucial roles in ameliorating the RIM-produced brightness (or power distribution); the two factors are associated with some radar parameters and system characteristics. The range/time delay of the signal was found to increase with time; moreover, it was slightly different for the echoes from the atmosphere with and without the presence of significant precipitation. A procedure of point-by-point correction of range/time delay was thus executed for the presence of precipitation to minimize the bogus brightness discontinuity at range gate boundaries. With the RIM technique, the Chung-Li VHF radar demonstrates its first successful observation of double-layer structures as well as their temporal and spatial variations with time.

  3. Generalized Chung-Feller Theorems for Lattice Paths (Thesis)

    CERN Document Server

    Huq, Aminul

    2009-01-01

    In this thesis we develop generalized versions of the Chung-Feller theorem for lattice paths constrained in the half plane. The beautiful cycle method which was developed by Devoretzky and Motzkin as a means to prove the ballot problem is modified and applied to generalize the classical Chung-Feller theorem. We use Lagrange inversion to derive the generalized formulas. For the generating function proof we study various ways of decomposing lattice paths. We also show some results related to equidistribution properties in terms of Narayana and Catalan generating functions. We then develop generalized Chung-Feller theorems for Motzkin and Schroeder paths. Finally we study generalized paths and the analogue of the Chung-Feller theorem for them.

  4. Lam Kin Chung Morning Sun China- Japan Friendship Fund Set up

    Institute of Scientific and Technical Information of China (English)

    2004-01-01

    <正>Lam Kin Chung Morning Sun Charity Fund of HoneKong has decided to donate, from January 2004, 100,000 RMB yuan each year for 5 consecutive years, which totals 500,000 RMB yuan, to set up the Lam Kin Chung Morning Sun China-Japan Friendship Fund under the China Friend-

  5. Edgeworth expansions and rates of convergence for normalized sums: Chung's 1946 method revisited

    OpenAIRE

    2010-01-01

    Abstract In this paper we revisit, correct and extend Chung?s 1946 method for deriving higher order Edgeworth expansions with respect to t-statistics and generalized self-normalized sums. Thereby we provide a set of formulas which allows the computation of the approximation of any order and specify the first four polynomials in the Edgeworth expansion the first two of which are well known. It turns out that knowledge of the first four polynomials is necessary and sufficient for cha...

  6. Analysis of Terminal Velocity and VHF Backscatter of Precipitation Particles Using Chung-Li VHF Radar Combined with Ground-Based Disdrometer

    Directory of Open Access Journals (Sweden)

    Ching-Lun Su and Yen-Hsyang Chu

    2007-01-01

    Full Text Available The backscatter from precipitation particles observed by the vertically pointed antenna beam of the Chung-Li VHF radar and the drop size distributions measured by a ground-based disdrometer co-located at the radar site are analyzed and studied in this article. We find that the disdrometermeasured drop size distribution can be well approximated to a Gamma distribution. On the basis of this property and a power law approximation to the fallspeed-diameter relation VD = ADB, we derive the theoretical relation between terminal velocity VD and range-corrected VHF backscatter P of the precipitation particles. We find that the VD - P relation follows a power law in the form of VD = _ where _ _ both the functions of the precipitation parameters. Chu et al. (1999 first found that the relation between _ _ be empirically approximated to an exponential form of _ _ where _ a function of B and _ a factor associated with precipitation. In this article, under the assumptions of the Gamma distribution of the drop size distribution and the power-law relation between VD and D, we theoretically show that the analytical relation between _ _ follows an exponential form of _ _ where _ a function of the drop size distribution. The experimental results obtained by the Chung-Li VHF radar combined with the ground-based disdrometer measurements validate the exponential approximation to the _ _ The uses of the _ _ for the investigations of the rainfall rate and properties of drop size distribution are presented and discussed.

  7. The "Yew Chung Model" of International Education: The Scope for Investigation and Research

    Science.gov (United States)

    Bunnell, Tristan

    2015-01-01

    The Yew Chung Education Foundation operates a network of five international schools in China, plus one in California, serving in total around 5500 children. This article investigates the aims and philosophy of a "model" of international education which aims not only to educate children but also to bring about an inner transformation of…

  8. Synthesis and bioactivity of diketopiperazine PJ147 and its derivatives from Gliocladium sp. YUP08.

    Science.gov (United States)

    Li, Xue-Zheng; Chen, Gang; Wang, Hai-Feng; Hua, Hui-Ming; Pei, Yue-Hu

    2014-01-01

    Concise total synthesis of diketopiperazine PJ147, obtained from mycelium of Gliocladium sp. YUP08, has been achieved in seven steps with 43.5% overall yield. Biological evaluation of PJ147 exhibited strong inhibiting activity against A375-S2, Hela, P388, A-549, HL-60, and BEL-7420 cell lines. Thus, eight derivatives of PJ147 with high water solubility were also synthesized to facilitate the in vivo bioassay of this kind of diketopiperazines.

  9. An In-Depth Analysis of the Chung-Lu Model

    Energy Technology Data Exchange (ETDEWEB)

    Winlaw, M. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); DeSterck, H. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Sanders, G. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States)

    2015-10-28

    In the classic Erd}os R enyi random graph model [5] each edge is chosen with uniform probability and the degree distribution is binomial, limiting the number of graphs that can be modeled using the Erd}os R enyi framework [10]. The Chung-Lu model [1, 2, 3] is an extension of the Erd}os R enyi model that allows for more general degree distributions. The probability of each edge is no longer uniform and is a function of a user-supplied degree sequence, which by design is the expected degree sequence of the model. This property makes it an easy model to work with theoretically and since the Chung-Lu model is a special case of a random graph model with a given degree sequence, many of its properties are well known and have been studied extensively [2, 3, 13, 8, 9]. It is also an attractive null model for many real-world networks, particularly those with power-law degree distributions and it is sometimes used as a benchmark for comparison with other graph generators despite some of its limitations [12, 11]. We know for example, that the average clustering coe cient is too low relative to most real world networks. As well, measures of a nity are also too low relative to most real-world networks of interest. However, despite these limitations or perhaps because of them, the Chung-Lu model provides a basis for comparing new graph models.

  10. Antiangiogenic mechanisms of PJ-8, a novel inhibitor of vascular endothelial growth factor receptor signaling.

    Science.gov (United States)

    Huang, Shiu-Wen; Lien, Jin-Cherng; Kuo, Sheng-Chu; Huang, Tur-Fu

    2012-05-01

    Angiogenesis occurs not only during tissue growth and development but also during wound healing and tumor progression. Angiogenesis is a balanced process controlled by proangiogenic and antiangiogenic molecules. As a critical factor in the induction of angiogenesis, vascular endothelial growth factor (VEGF) has become an attractive target for antiangiogenic and cancer therapeutic agents. In an effort to develop novel inhibitors to block VEGF signaling, we selected Pj-8, a benzimidazole derivative, and investigated its inhibitory mechanisms in human umbilical vascular endothelial cells (HUVECs). Pj-8 concentration-dependently inhibited VEGF-induced proliferation, migration and tube formation of HUVECs. Pj-8 also suppressed VEGF-induced microvessel sprouting from aortic rings ex vivo and suppressed neovascularization of implanted matrigel plugs in vivo. Pj-8 inhibited VEGF-induced phosphorylation of VEGF receptor (VEGFR) 2 and the downstream protein kinases, including Akt, focal adhesion kinase, extracellular signal-regulated kinases and Src. Results from in vitro kinase assay further demonstrated that Pj-8 suppressed the kinase activity of 3-phosphoinositide-dependent kinase 1 (PDK1). Using xenograft tumor angiogenesis model, Pj-8 markedly eliminated tumor-associated angiogenesis. Taken together, our findings suggest that Pj-8 inhibits VEGF and tumor cells MDA-MB-231-induced angiogenesis, and it may be a potential drug candidate in anticancer therapy. Downregulation of VEGFR2-mediated signaling may contribute to its antiangiogenic actions.

  11. L’écrivain palimpseste dans L’expérience interdite d’Ook Chung

    Directory of Open Access Journals (Sweden)

    Gilles Dupuis

    2017-03-01

    Full Text Available Dans son roman L’expérience interdite, Ook Chung introduit deux figures inédites d’écrivain fictif dans la littérature québécoise contemporaine, inspirées des cultures japonaise et himalayenne : l’otaku (ou hikikomori et le mythique Yéti. Il imagine également une fiction dystopique gravitant autour de la figure de « l’écrivain encagé », qui emprunte ses traits au roman de science-fiction de H. G. Wells, L’île du docteur Moreau. À travers une lecture de ce roman qui interroge son statut générique (entre autofiction et science-fiction et ses procédés littéraires (parodie et réécriture, il s’agit d’éclairer les diverses figures de l’écrivain fictif qui s’y profilent en relation avec celle de l’auteur. In his novel L’expérience interdite, Ook Chung introduces two new figures of the fictional writer, inspired by Japanese and Himalayan cultures, into contemporary Québécois literature: the otaku (or hikikomori and the mythical Yeti. The novel also portrays the dystopian figure of the “imprisoned” writer, which recalls H. G. Wells’ science fiction novel, The Island of Doctor Moreau. The aim of this article is to shed light on the different figures of the fictional writer encountered in Chung’s fiction in relation to that of the author, by questioning the generic status (between autofiction and science fiction and literary devices (parody and rewriting of the novel.

  12. 亲爱的忧郁PJ Harvey之《White Chalk》

    Institute of Scientific and Technical Information of China (English)

    2007-01-01

    @@ 听到"Dear Darkness"时,如往常一样拉扯并且战栗的女声却分明地陌生起来.许多期待着她的人都能顿时明白,这是一个新的PJ Harvey.她冷得像冰凉潮湿的雨季,而她的音乐给人的药效,开始倾向于一种致命和快速.中庸点讲,这样镇静冷漠的PJ Harvey,可以持续更久.

  13. Data of evolutionary structure change: 3GD5D-3E2PJ [Confc[Archive

    Lifescience Database Archive (English)

    Full Text Available 3GD5D-3E2PJ 3GD5 3E2P D J TRFRPDLLSLDDLDEAQLHALLTLAHQLKRGE---RVAN...-LHGKVLGLVFLKASTRTRVSFTVAMYQLGGQVIDL-----------EPVRDTARVLGRYVDGLAIRTFAQTELEEYAHYAGIPVINALTD-HEHPCQVVADLLTIRENFGRLAGLKLAYVGD...ISMKDIGKEEILEILDEARKMEELLNTKRPLKLLEGKILATVFYEPSTRTRLSFETAMKRLGGEVITMTDLKSSSVAKGESLIDTIRVISGYADIIVLRHPSEGAARLASEYSQVPIINAGD...GSNQHPTQTLLDLYTIMREIGRIDGIKIAFVGDLKYGRTVHSLVYALSLFENVEMYFVSPKELRLPKDIIEDLKAK----NIKFYEKESLDDLD...ex> 3GD5 D 3GD5D YVGD

  14. ma a

    Directory of Open Access Journals (Sweden)

    Oscar del Barco, Trad. Davi Pessoa Carneiro

    2013-06-01

    Full Text Available Oscar del Barco escreveu o texto “ma a” para o catálogo ma a/Obra pictórica (Cór­doba, 2008, publicado na ocasião da exposição homônima, em que foram ex­postas 150 obras iné­ditas de distintos formatos e técnicas que del Barco vinha reali­zando há mais de 15 anos. Alguns escritores, artistas, ensaís­tas e pesquisadores, como Silvio Mattoni, Antonio Oviedo, Anamaría Ashwell, Gustavo Cosa­cov, Matías Lapezzata, entre outros, parti­ciparam da publi­cação. O texto foi posteriormente in­cluído em Alternativas de lo Posthumano (Buenos Aires: Caja Negra, 2010, com organização de Gabriel Livov e Pablo Gallardo. A tradução é do texto pu­blicado no mesmo livro (p. 279-283. [N.T.

  15. Effects of Chung-Pae Inhalation Therapy on a Mouse Model of Chronic Obstructive Pulmonary Disease.

    Science.gov (United States)

    Hwang, Joon-Ho; Lee, Beom-Joon; Jung, Hee Jae; Kim, Kwan-Il; Choi, Jun-Yong; Joo, Myungsoo; Jung, Sung-Ki

    2015-01-01

    Chung-pae (CP) inhalation therapy is a method frequently used in Korea to treat lung disease, especially chronic obstructive pulmonary disease (COPD). This study investigated the effects of CP inhalation on a COPD animal model. C57BL/6 mice received porcine pancreatic elastase (PPE) and lipopolysaccharide (LPS) alternately three times for 3 weeks to induce COPD. Then, CP (5 or 20 mg/kg) was administered every 2 h after the final LPS administration. The effect of CP was evaluated by bronchoalveolar lavage (BAL) fluid analysis, histological analysis of lung tissue, and reverse transcription polymerase chain reaction analysis of mRNA of interleukin- (IL-) 1β, tumor necrosis factor- (TNF-) α, IL-6, and tumor growth factor- (TGF-) β. Intratracheal CP administration reduced the number of leukocytes and neutrophils in BAL fluid, inhibited the histological appearance of lung damage, and decreased the mRNA levels of the proinflammatory cytokines IL-1β, TNF-α, IL-6, and TGF-β. Intratracheal CP administration effectively decreased the chronic inflammation and pathological changes in a PPE- and LPS-induced COPD mouse model. Therefore, we suggest that CP is a promising strategy for COPD.

  16. Intervention timing and effect of PJ34 on astrocytes during oxygen-glucose deprivation/reperfusion and cell death pathways.

    Science.gov (United States)

    Cai, Chuan; Zhang, Rui; Huang, Qiao-Ying; Cao, Xu; Zou, Liang-Yu; Chu, Xiao-Fan

    2015-06-01

    Poly (ADP-ribose) polymerase-1 (PARP-1) plays as a double edged sword in cerebral ischemia-reperfusion, hinging on its effect on the intracellular energy storage and injury severity, and the prognosis has relationship with intervention timing. During ischemia injury, apoptosis and oncosis are the two main cell death pathway sin the ischemic core. The participation of astrocytes in ischemia-reperfusion induced cell death has triggered more and more attention. Here, we examined the protective effects and intervention timing of the PARP-1 inhibitor PJ34, by using a mixed oxygen-glucose deprivation/reperfusion (OGDR) model of primary rat astrocytes in vitro, which could mimic the ischemia-reperfusion damage in the "ischemic core". Meanwhile, cell death pathways of various PJ34 treated astrocytes were also investigated. Our results showed that PJ34 incubation (10 μmol/L) did not affect release of lactate dehydrogenase (LDH) from astrocytes and cell viability or survival 1 h after OGDR. Interestingly, after 3 or 5 h OGDR, PJ34 significantly reduced LDH release and percentage of PI-positive cells and increased cell viability, and simultaneously increased the caspase-dependent apoptotic rate. The intervention timing study demonstrated that an earlier and longer PJ34 intervention during reperfusion was associated with more apparent protective effects. In conclusion, earlier and longer PJ34 intervention provides remarkable protective effects for astrocytes in the "ischaemic core" mainly by reducing oncosis of the astrocytes, especially following serious OGDR damage.

  17. Pengaruh Pembelajaran Project Based Learning (PjBL pada Materi Ekosistem terhadap Sikap dan Hasil Belajar Siswa SMAN 2 Malang

    Directory of Open Access Journals (Sweden)

    Susriyati Mahanal

    2010-05-01

    Full Text Available The objective of this research was to know the effect of Project Based Learning (PjBL to the attitude and student cognitive achievement in SMAN 2 Malang. This research applied quasy experimental with non-equivalent control group design. The populations of this research is all student of class X SMAN 2 Malang on academic year 2008/2009. The samples of this research were class X7 as experimental (PjBL and class X8 as control (conventional. The instrument of this research namely cognitive achievement test and attitude scale questionnaire to river ecosystem. This research data are quantitative data consisted by score cognitive achievement and attitude scale questionnaire to river ecosystem, collected on 14 Maret until 31 May 2009. Data were analysed by bilinear covariant statistical analysis (Ancova, continued with LSD test. The result of this research indicated that there were PjBL toward the cognitive achievement and student attitude to river ecosystem. Students with PjBl having attitude higher 11,65% from conventional students. Beside, students with PjBl having cognitive achievement higher 81,05% from conventional students. Based on this research, the researcher suggest to the teacher that this strategy can be implemented in biology learning.   Kata kunci: Project Based Learning, sikap terhadap ekosistem sungai, hasil belajar

  18. Daytime E-Region Irregularities During the 22 July 2009 Solar Eclipse over Chung-Li (24.9°N, 121.2°E, a Moderate Mid-Latitude Station

    Directory of Open Access Journals (Sweden)

    Potula Sree Brahmanandam

    2013-01-01

    Full Text Available The 22 July 2009 solar eclipse with an obscuration of > 83% at Chung-Li (24.9¢XN, 121.2¢XE, Dip 35¢XN in Taiwan during noon hours has provided a unique opportunity for us to examine its impact on E-region irregularities which were observed simultaneously by the 52 MHz coherent radar and a co-located ionosonde. Significant observations revealed that the daytime E-region strong backscatter echoes at multiple heights and a sudden intensification of the weak sporadic E-layer during the 22 July 2009 solar eclipse. These results follow the research findings of Patra et al. (2009. As the incident solar radiation suddenly blocked by intruding Moon during solar eclipse events that would generally create night-like ionospheric conditions, it is surmised that the E-region irregularities were indeed induced by the eclipse associated effects. The induced effects resulted in faster recombination of molecular ions, generation of gravity waves and electric fields that could have created a conducive environment to excite plasma irregularities through a gradient-drift instability mechanism. The vertical shears of radar Doppler velocity and the peak radar backscatter at the node of Doppler velocity shear, as resolved by the coherent scatter radar with interferometer technique, were possibly due to the upward propagating gravity waves and wave-induced polarization electric fields. The present observational results should not only be highly useful to ascertain plausible mechanisms responsible for nighttime E-region irregularities, but also provided evidence that a solar eclipse could generate E-region plasma irregularities over temperate mid-latitudes for the first time.

  19. Understanding plasma spraying process and characteristics of DC-arc plasma gun (PJ-100

    Directory of Open Access Journals (Sweden)

    Jovana Ružić

    2012-12-01

    Full Text Available The thermal spray processes are a group of coating processes used to apply metallic or non-metallic coatings. In these processes energy sources are used to heat the coating material (in the form of powder, wire, or rod form to a molten or semi-molten state and accelerated towards a prepared surface by either carrier gases or atomization jets. In plasma spraying process, the spraying material is generally in the form of powder and requires a carrier gas to feed the powder into the plasma jet, which is passing between the hot cathode and the cylindrical nozzle-shaped anode. The design of DC plasma gun (PJ - 100 is designed and manufactured in Serbia. Plasma spaying process, the powder injection with the heat, momentum and mass transfers between particles and plasma jet, and the latest developments related to the production of DC plasma gun are described in this article.

  20. Frataxin Deficiency Promotes Excess Microglial DNA Damage and Inflammation that Is Rescued by PJ34.

    Directory of Open Access Journals (Sweden)

    Yan Shen

    Full Text Available An inherited deficiency in the frataxin protein causes neurodegeneration of the dorsal root ganglia and Friedreich's ataxia (FA. Frataxin deficiency leads to oxidative stress and inflammatory changes in cell and animal models; however, the cause of the inflammatory changes, and especially what causes brain microglial activation is unclear. Here we investigated: 1 the mechanism by which frataxin deficiency activates microglia, 2 whether a brain-localized inflammatory stimulus provokes a greater microglial response in FA animal models, and 3 whether an anti-inflammatory treatment improves their condition. Intracerebroventricular administration of LPS induced higher amounts of microglial activation in the FA mouse model vs controls. We also observed an increase in oxidative damage in the form of 8-oxoguanine (8-oxo-G and the DNA repair proteins MUTYH and PARP-1 in cerebellar microglia of FA mutant mice. We hypothesized that frataxin deficiency increases DNA damage and DNA repair genes specifically in microglia, activating them. siRNA-mediated frataxin knockdown in microglial BV2 cells clearly elevated DNA damage and the expression of DNA repair genes MUTYH and PARP-1. Frataxin knockdown also induced a higher level of PARP-1 in MEF cells, and this was suppressed in MUTYH-/- knockout cells. Administration of the PARP-1 inhibitor PJ34 attenuated the microglial activation induced by intracerebroventricular injection of LPS. The combined administration of LPS and angiotensin II provoke an even stronger activation of microglia and neurobehavioral impairment. PJ34 treatment attenuated the neurobehavioral impairments in FA mice. These results suggest that the DNA repair proteins MUTYH and PARP-1 may form a pathway regulating microglial activation initiated by DNA damage, and inhibition of microglial PARP-1 induction could be an important therapeutic target in Friedreich's ataxia.

  1. Small PARP inhibitor PJ-34 induces cell cycle arrest and apoptosis of adult T-cell leukemia cells.

    Science.gov (United States)

    Bai, Xue Tao; Moles, Ramona; Chaib-Mezrag, Hassiba; Nicot, Christophe

    2015-10-23

    HTLV-I is associated with the development of an aggressive form of lymphocytic leukemia known as adult T-cell leukemia/lymphoma (ATLL). A major obstacle for effective treatment of ATLL resides in the genetic diversity of tumor cells and their ability to acquire resistance to chemotherapy regimens. As a result, most patients relapse and current therapeutic approaches still have limited long-term survival benefits. Hence, the development of novel approaches is greatly needed. In this study, we found that a small molecule inhibitor of poly (ADP-ribose) polymerase (PARP), PJ-34, is very effective in activating S/G2M cell cycle checkpoints, resulting in permanent cell cycle arrest and reactivation of p53 transcription functions and caspase-3-dependent apoptosis of HTLV-I-transformed and patient-derived ATLL tumor cells. We also found that HTLV-I-transformed MT-2 cells are resistant to PJ-34 therapy associated with reduced cleaved caspase-3 activation and increased expression of RelA/p65. Since PJ-34 has been tested in clinical trials for the treatment of solid tumors, our results suggest that some ATLL patients may be good candidates to benefit from PJ-34 therapy.

  2. The PARP inhibitor PJ-34 sensitizes cells to UVA-induced phototoxicity by a PARP independent mechanism.

    Science.gov (United States)

    Lakatos, Petra; Hegedűs, Csaba; Salazar Ayestarán, Nerea; Juarranz, Ángeles; Kövér, Katalin E; Szabó, Éva; Virág, László

    2016-08-01

    A combination of a photosensitizer with light of matching wavelength is a common treatment modality in various diseases including psoriasis, atopic dermatitis and tumors. DNA damage and production of reactive oxygen intermediates may impact pathological cellular functions and viability. Here we set out to investigate the role of the nuclear DNA nick sensor enzyme poly(ADP-ribose) polymerase 1 in photochemical treatment (PCT)-induced tumor cell killing. We found that silencing PARP-1 or inhibition of its enzymatic activity with Veliparib had no significant effect on the viability of A431 cells exposed to 8-methoxypsoralen (8-MOP) and UVA (2.5J/cm(2)) indicating that PARP-1 is not likely to be a key player in either cell survival or cell death of PCT-exposed cells. Interestingly, however, another commonly used PARP inhibitor PJ-34 proved to be a photosensitizer with potency equal to 8-MOP. Irradiation of PJ-34 with UVA caused changes both in the UV absorption and in the 1H NMR spectra of the compound with the latter suggesting UVA-induced formation of tautomeric forms of the compound. Characterization of the photosensitizing effect revealed that PJ-34+UVA triggers overproduction of reactive oxygen species, induces DNA damage, activation of caspase 3 and caspase 8 and internucleosomal DNA fragmentation. Cell death in this model could not be prevented by antioxidants (ascorbic acid, trolox, glutathione, gallotannin or cell permeable superoxide dismutase or catalase) but could be suppressed by inhibitors of caspase-3 and -8. In conclusion, PJ-34 is a photosensitizer and PJ-34+UVA causes DNA damage and caspase-mediated cell death independently of PARP-1 inhibition.

  3. The PARP inhibitor PJ-34 sensitizes cells to UVA-induced phototoxicity by a PARP independent mechanism

    Energy Technology Data Exchange (ETDEWEB)

    Lakatos, Petra; Hegedűs, Csaba [Department of Medical Chemistry, Faculty of Medicine, University of Debrecen, Debrecen (Hungary); Salazar Ayestarán, Nerea; Juarranz, Ángeles [Department of Biology, Faculty of Sciences, Universidad Autónoma of Madrid, 28049-Madrid (Spain); Kövér, Katalin E. [Department of Inorganic and Analytical Chemistry, Faculty of Sciences, University of Debrecen, Debrecen (Hungary); Szabó, Éva [Department of Dermatology, Faculty of Medicine, University of Debrecen, Debrecen (Hungary); Virág, László, E-mail: lvirag@med.unideb.hu [Department of Medical Chemistry, Faculty of Medicine, University of Debrecen, Debrecen (Hungary); MTA-DE Cell Biology and Signaling Research Group, Debrecen (Hungary)

    2016-08-15

    Highlights: • PARP-1 is not a key regulator of photochemotherapy. • The PARP inhibitor PJ-34 sensitizes cells to UVA-induced phototoxicity by a PARP independent mechanism. • Photosensitization by PJ-34 is associated with increased ROS production and DNA damage. • Cells sensitized by PJ-34 undergo caspase-mediated apoptosis. - Abstract: A combination of a photosensitizer with light of matching wavelength is a common treatment modality in various diseases including psoriasis, atopic dermatitis and tumors. DNA damage and production of reactive oxygen intermediates may impact pathological cellular functions and viability. Here we set out to investigate the role of the nuclear DNA nick sensor enzyme poly(ADP-ribose) polymerase 1 in photochemical treatment (PCT)-induced tumor cell killing. We found that silencing PARP-1 or inhibition of its enzymatic activity with Veliparib had no significant effect on the viability of A431 cells exposed to 8-methoxypsoralen (8-MOP) and UVA (2.5 J/cm{sup 2}) indicating that PARP-1 is not likely to be a key player in either cell survival or cell death of PCT-exposed cells. Interestingly, however, another commonly used PARP inhibitor PJ-34 proved to be a photosensitizer with potency equal to 8-MOP. Irradiation of PJ-34 with UVA caused changes both in the UV absorption and in the 1H NMR spectra of the compound with the latter suggesting UVA-induced formation of tautomeric forms of the compound. Characterization of the photosensitizing effect revealed that PJ–34 + UVA triggers overproduction of reactive oxygen species, induces DNA damage, activation of caspase 3 and caspase 8 and internucleosomal DNA fragmentation. Cell death in this model could not be prevented by antioxidants (ascorbic acid, trolox, glutathione, gallotannin or cell permeable superoxide dismutase or catalase) but could be suppressed by inhibitors of caspase-3 and −8. In conclusion, PJ-34 is a photosensitizer and PJ–34 + UVA causes DNA damage and caspase

  4. Biogeochemical characteristics of Kuan-Tzu-Ling, Chung-Lun and Bao-Lai hot springs in southern Taiwan.

    Science.gov (United States)

    Maity, Jyoti Prakash; Liu, Chia-Chuan; Nath, Bibhash; Bundschuh, Jochen; Kar, Sandeep; Jean, Jiin-Shuh; Bhattacharya, Prosun; Liu, Jiann-Hong; Atla, Shashi B; Chen, Chien-Yen

    2011-01-01

    Hot springs are the important natural sources of geothermally heated groundwater from the Earth's crust. Kuan-Tzu-Ling (KTL), Chung-Lun (CL) and Bao-Lai (BL) are well-known hot springs in southern Taiwan. Fluid and mud (sediments) samples were collected from the eruption points of three hot springs for detailed biogeochemical characterization. The fluid sample displays relatively high concentrations of Na(+) and Cl(-) compared with K(+), Mg(2+), Ca(2+), NO(2) (-), and SO(4) (2-), suggesting a possible marine origin. The concentrations of Fe, Cr, Mn, Ni, V and Zn were significantly higher in the mud sediments compared with fluids, whereas high concentrations of As, Ba, Cu, Se, Sr and Rb were observed in the fluids. This suggests that electronegative elements were released during sediment-water interactions. High As concentration in the fluids was observed to be associated with low redox (Eh) conditions. The FTIR spectra of the humic acid fractions of the sediments showed the presence of possible functional groups of secondary amines, ureas, urethanesm (amide), and silicon. The sulfate-reducing deltaproteobacterium 99% similar to Desulfovibrio psychrotolerans (GU329907) were rich in the CL hot spring while mesophilic, proteolytic, thiosulfate- and sulfur-reducing bacterium that 99% similar to Clostridium sulfidigenes (GU329908) were rich in the BL hot spring.

  5. Ch'ien Chung-shu's View of "Talent and Learning"%钱钟书论"才与学"

    Institute of Scientific and Technical Information of China (English)

    陈颖

    2015-01-01

    Ch'ien Chung-shu's found the different theories about "talent and learning" in the multitude of classical literary theory dis-courses,and he carried out discourse communication and innovation in his vision from the perspective of modern art,which effectively activated and promoted the traditional literary theory proposition about"talent and learning", not only opening up a new way for search-ing deep theoretical meaning of literature creation conditions,but also providing new perspective and enlightenment for the study of crea-tion rules.%钱钟书在浩如烟海的古典文论话语中,独具慧眼地拈出了"才而不学"与"才须学也"这来自两极的理论言说,并以宏阔现代的眼光对这一对理论话语进行会通与创化,有效地激活并提升了"才与学"的传统文论命题,为我们探寻文学创作主体条件的深层理论奥义开拓了一条崭新的途径,为创作规律研究提供了新鲜的视角与启示.

  6. PJ-200、GJ-190高墩模板墩身施工技术

    Institute of Scientific and Technical Information of China (English)

    潘建平

    2012-01-01

    渝利铁路向家坝双线大桥设计为空心薄壁高墩,墩高75.5m,采用PJ -200、GJ-190高墩悬臂模板分节施工.本文结合工程实际,介绍了该高墩悬臂模板结构的设计特点和施工工艺.

  7. MaXi Avisen

    DEFF Research Database (Denmark)

    Kanstrup, Anne Marie; Sørensen, Marianne; Bertelsen, Pernille

    2008-01-01

    maXi-projektets vision er at sprænge rammerne for sundhedsstøtte med it ved at sætte diabetikere og deres familier i centrum og ved at flytte fokus fra sygdom og hospitaler til samfund, hverdagsliv og services. maXi-projektet har til formål at afprøve og gennemføre brugerdreven innovation som...... eksperimenter i et 'living lab' - som etableres i Skagen. I 2009 udvælges nye brugere til deltagelse i projektet. maXi-projektet opbygges som et modelprojekt i samar-bejde mellem Aalborg Universitet, Fonden Skagen Helse, Teknologisk Institut og Edvantage Group. Se http://www.maxi-projektet.dk/ Projektet er...

  8. 钟理和日记与创伤记忆%The Traumatic Memory:A Reading of the Diary of Chung Li-ho

    Institute of Scientific and Technical Information of China (English)

    计璧瑞

    2015-01-01

    Based on analyses of the new version of the Diary of Chung Li-ho, this paper attempts to explore Chung Li-ho’s spiritual status and the trajectory of his memories, and to use the concept of“traumatic memory”to demonstrate that Chung Li-ho’s diary is a record of traumatic memories in his life. This paper synthesizes the times, the places and the living conditions when Chung Li-ho wrote his diaries, divides them into four periods, and illustrates that the content and focus of the diary varies from different periods.“The traumatic memory”are the common thread running through the last three periods of the diary. This kind of memories continuously overlapped, difficult to avoid, and constantly reemerged. It is through writing that Chung Li-ho gave vent to and relieve his spiritual suf ferings resulted from traumatic memories, and thus writing and recording became his spiritual therapy to the traumas . The individual“traumatic memory”of Chung Li-ho has become a metaphor through constant discussions and narratives of later Taiwanese writers, and has been turned into a collective memory of Taiwan literature.%本文尝试以“新版钟理和日记”为分析中心,从所记录的事件、风物、生活细节和情感经验去探究钟理和的记忆轨迹和精神状态,借用“创伤记忆”论述说明钟理和日记其实是作者人生创伤记忆的记录,兼论日记与书简的不同功能。本文综合钟理和日记的写作时间、地点和写作时的生活状态,将其划分为四个时段,说明不同时段日记的书写内容和关注点也各有不同;“创伤记忆”是贯穿钟理和日记后三个时段的中心内容,它们不断叠加、难以摆脱、重复再现;钟理和正是以书写的方式宣泄和纾解创伤记忆导致的精神痛苦,写作和记录就是一种精神的疗伤。钟理和个人的“创伤记忆”在后人的持续论述中成为隐喻,成为台湾文学的集体记忆。

  9. YI Suki's Yŏksimanpil and the Professional Identity of a Chung'in Medical Official in Eighteenth Century Chosŏn Korea.

    Science.gov (United States)

    Yi, Kiebok

    2013-08-01

    About one hundred years after the publication of Tongŭibogam (1613), a physician at the court YI Suki (1664-?) wrote a medical manuscript titled Yŏksimanpil (Miscellaneous Jottings on Medical Experiences and Tests, 1734). As indicated in its title, Yŏksimanpil was a medical essay composed of 130 medical case histories, drawing on what YI Suki himself had experienced in his medical practices. This paper examines the messages YI Suki in Yŏksimanpil tried to address to his fellow Korean doctors, and by doing so illuminates an aspect of the medicine in the late Chosŏn period. The argument goes that YI Suki wrote Yŏksimanpil as a vehicle for promulgating his professional identity as a bureaucratic physician who belonged to the network of the chung'in technical officials-a group of government technical functionaries in late Chosŏn Korea. Throughout the late Chosŏn period, the chung'in technical officials had been discriminated, institutionally and socioculturally, against the yangban literati, while their promotion to honored higher positions was blocked. It was in the late 17th and early 18th century that a group of chung'in officials tried to secure their sociocultural places for their professional activity, thus bringing to light their social and professional identity in Chosŏn society. A member of the network of the chung'in technical officials in the early 18th century, YI Suki was in an effort to position himself as a doctor somewhere between the medical tradition and the Confucian literary tradition. In these sociocultural contexts, we can see more clearly what YI Suki tried to speak of in his book and the historical meaning of the medical writing Yŏksimanpil. First, the way he practiced medicine was testing and confirming what the received medical textbooks had asserted (Chŭnghŏmkobang). This style of practicing medicine could be viewed as a reflection of the comprehensivity trait of bureaucratic court physicians network YI Suki belonged to. Also this

  10. MaTeam-projektet

    DEFF Research Database (Denmark)

    Andreasen, Marikka; Damkjær, Helle Sejer; Højgaard, Tomas

    2011-01-01

    Projektet MaTeam beskrives med fokus på et toårigt forsøg hvor matematiklærerne på 4.-6. klassetrin på fire skoler i Silkeborg Kommune samarbejdede med forfatterne. Projektet handlede om udvikling af matematiklærerkompetencer med fokus på samarbejdet i de fire skolers matematiklærerfagteam...... matematiklærerfagteam og samarbejdsrelationer der indgår i projektet. Desuden beskriver vi forskellige typer af fagteam og lærere. Metodisk var MaTeam-projektet struktureret som en didaktisk modelleringsproces....

  11. MaXi Avisen

    DEFF Research Database (Denmark)

    Kanstrup, Anne Marie; Sørensen, Marianne

    2008-01-01

    eksperimenter i et 'living lab' - som etableres i Skagen. I 2009 udvælges nye brugere til deltagelse i projektet. maXi-projektet opbygges som et modelprojekt i samar-bejde mellem Aalborg Universitet, Fonden Skagen Helse, Teknologisk Institut og Edvantage Group. Se http://www.maxi-projektet.dk/ Projektet er...

  12. Woman Director Ma Yueying

    Institute of Scientific and Technical Information of China (English)

    1995-01-01

    Ma Yueying took office as director of the Jiaxing General Silk Mill, which had 200,000 yuan capital fund, in 1975. Since then, this mill has developed greatly. Now it has become an advanced enterprise with an annual output worth RMB¥30 million and fixed assets of RMB¥10 million.

  13. Laser Spectroscopy of the Fine-Structure Splitting in the 2 PJ 3 Levels of He 4

    Science.gov (United States)

    Zheng, X.; Sun, Y. R.; Chen, J.-J.; Jiang, W.; Pachucki, K.; Hu, S.-M.

    2017-02-01

    The fine-structure splitting in the 2 PJ 3 (J =0 , 1, 2) levels of He 4 is of great interest for tests of quantum electrodynamics and for the determination of the fine-structure constant α . The 2 P0 3 -2 P2 3 and 2 P1 3 -2 P2 3 intervals are measured by laser spectroscopy of the PJ 3 -2 S1 3 transitions at 1083 nm in an atomic beam, and are determined to be 31 908 130.98 ±0.13 kHz and 2 291 177.56 ±0.19 kHz , respectively. Compared with calculations, which include terms up to α5Ry , the deviation for the α -sensitive interval 2 P0 3 -2 P2 3 is only 0.22 kHz. It opens the window for further improvement of theoretical predictions and an independent determination of the fine-structure constant α with a precision of 2 ×10-9 .

  14. Application of the PJ and NPS evaporation duct models over the South China Sea (SCS) in winter.

    Science.gov (United States)

    Yang, Shaobo; Li, Xingfei; Wu, Chao; He, Xin; Zhong, Ying

    2017-01-01

    The detection of duct height has a significant effect on marine radar or wireless apparatus applications. The paper presents two models to verify the adaptation of evaporation duct models in the SCS in winter. A meteorological gradient instrument used to measure evaporation ducts was fabricated using hydrological and meteorological sensors at different heights. An experiment on the adaptive characteristics of evaporation duct models was carried out over the SCS. The heights of the evaporation ducts were measured by means of log-linear fit, Paulus-Jeske (PJ) and Naval Postgraduate School (NPS) models. The results showed that NPS model offered significant advantages in stability compared with the PJ model. According the collected data computed by the NPS model, the mean deviation (MD) was -1.7 m, and the Standard Deviation (STD) of the MD was 0.8 m compared with the true value. The NPS model may be more suitable for estimating the evaporation duct height in the SCS in winter due to its simpler system characteristics compared with meteorological gradient instruments.

  15. [MaRS Project

    Science.gov (United States)

    Aruljothi, Arunvenkatesh

    2016-01-01

    The Space Exploration Division of the Safety and Mission Assurances Directorate is responsible for reducing the risk to Human Space Flight Programs by providing system safety, reliability, and risk analysis. The Risk & Reliability Analysis branch plays a part in this by utilizing Probabilistic Risk Assessment (PRA) and Reliability and Maintainability (R&M) tools to identify possible types of failure and effective solutions. A continuous effort of this branch is MaRS, or Mass and Reliability System, a tool that was the focus of this internship. Future long duration space missions will have to find a balance between the mass and reliability of their spare parts. They will be unable take spares of everything and will have to determine what is most likely to require maintenance and spares. Currently there is no database that combines mass and reliability data of low level space-grade components. MaRS aims to be the first database to do this. The data in MaRS will be based on the hardware flown on the International Space Stations (ISS). The components on the ISS have a long history and are well documented, making them the perfect source. Currently, MaRS is a functioning excel workbook database; the backend is complete and only requires optimization. MaRS has been populated with all the assemblies and their components that are used on the ISS; the failures of these components are updated regularly. This project was a continuation on the efforts of previous intern groups. Once complete, R&M engineers working on future space flight missions will be able to quickly access failure and mass data on assemblies and components, allowing them to make important decisions and tradeoffs.

  16. Characterization, gene cloning, and sequencing of a fungal phytase, PhyA, from Penicillium oxalicum PJ3.

    Science.gov (United States)

    Lee, Seung Ho; Cho, Jaiesoon; Bok, Jinduck; Kang, Seungha; Choi, Yunjaie; Lee, Peter C W

    2015-01-01

    A phytase from Penicillium oxalicum PJ3, PhyA, was purified near to homogeneity with 427-fold increase in specific phytase activity by ammonium sulfate precipitation, gel filtration, and ion-exchange chromatographies. Sodium dodecyl sulfate polyacrylamide gel electrophoresis (SDS-PAGE) and zymogram analysis of the purified enzyme indicated an estimated molecular mass of 65 kD. The optimal pH and temperature of the purified enzyme were pH 4.5 and 55°C, respectively. The enzyme activity was strongly inhibited by Ca(2+), Cu(2+), Zn(2+), and phenylmethylsulfonyl fluoride (PMSF). The Km value for sodium phytate was 0.545 mM with a Vmax of 600 U/mg of protein. The phyA gene was cloned, and it contains an open reading frame of 1,383 with a single intron (118 bp), and encodes a protein of 461 amino acids.

  17. Effect of fermentation with Saccharomyces cerevisiae strain PJ69-4 on the phytic acid, raffinose, and stachyose contents of soybean meal

    Science.gov (United States)

    Three experiments were conducted to determine the impact of submerged fermentation procedures using Saccharomyces cerevisiae baker’s yeast strain PJ69-4a on degradation of phytic acid and the raffinosaccharides, raffinose, and stachyose, in soybean meal. The goal of the research was to identify a n...

  18. Discovery and utilization of sorghum genes (Ma5/Ma6)

    Science.gov (United States)

    Mullet, John E; Rooney, William L; Klein, Patricia E; Morishige, Daryl; Murphy, Rebecca; Brady, Jeff A

    2012-11-13

    Methods and composition for the production of non-flowering or late flowering sorghum hybrid. For example, in certain aspects methods for use of molecular markers that constitute the Ma5/Ma6 pathway to modulate photoperiod sensitivity are described. The invention allows the production of plants having improved productivity and biomass generation.

  19. Kinetics of the Cl(2)P(J)) + CH4 Reaction: Effects of Secondary Chemistry Below 300 K

    Science.gov (United States)

    Wang, J. J.; Keyser, Leon F.

    2000-01-01

    Absolute rate data for the Cl(2)P(J) + CH4 yields HCl + CH3 reaction have been obtained from 218 to 298 K by using the discharge-flow resonance fluorescence technique at I Torr total pressure. The result at 298 K is (10.1 +/- 0.6) x 10(exp -14) cu cm/molecule/s. The temperature dependence in Arrhenius form is (6.5 +/- 0.9 ) x 10(exp -12) exp[(-1235 +/- 34 )/T]. The errors given are one standard deviation; overall experimental error is estimated at +/- 15%. Because of the relatively large disagreement among earlier measurements at low temperatures, the results were examined for possible effects of non-Boltzmann spin distribution and vibrational excitation of CH4, secondary chemistry of CH3 radicals, and impurities in the CH4 source. There was no significant change in the observed rate constant when an efficient spin quencher, CF4, was added and estimates indicate that vibrational partitioning in CH4 should be at the ambient reactor temperature before the start of the reaction. The results were also independent of the source of Cl atoms (microwave discharge or thermal decomposition of Cl2) and whether CH4 was purified in-situ. However, the observed rate constant did depend on initial Cl atom concentrations and to a lesser extent on CH4 concentrations. Numerical simulations were used to assess the importance of secondary chemistry over a range of reactant concentrations

  20. Upregulation of Salmonella-Induced IL-6 Production in Caco-2 Cells by PJ-34, PARP-1 Inhibitor: Involvement of PI3K, p38 MAPK, ERK, JNK, and NF-κB

    Directory of Open Access Journals (Sweden)

    Fu-Chen Huang

    2009-01-01

    Full Text Available Following Salmonella invasion, intestinal epithelial cells release a distinct array of proinflammatory cytokines. Interleukin (IL-6 produced by enterocytes may have anti-inflammatory and cell-protective effects, and may counteract some of the injurious effects of sepsis and endotoxemia. Recent studies in a variety of rodent models of experimental colitis by using PJ-34, a potent poly (ADP-ribose polymerase-1 (PARP-1 inhibitor, support the concept that the marked beneficial effect of PJ-34 can be exploited to treat human inflammatory diseases. The present study was to investigate the effect of PJ-34 on Salmonella-induced enterocyte IL-6 production and its mechanisms. We found that PJ-34 enhanced Salmonella-induced IL-6 production in Caco-2 cells, either secreted protein or mRNA expression. PJ-34 treatment enhanced the activity of NF-κB in Salmonella-infected Caco-2 cells. Besides, the involvement of PJ-34 in up-regulating IL-6 production in S. typhimurium-infected Caco-2 cells might be also through the ERK but not p38 MAPK, JNK or PI3K/Akt pathways, as demonstrated by Western blot of phosphorylated ERK, p38, JNK and Akt proteins. It suggests that PJ-34 may exert its protective effect on intestinal epithelial cells against invasive Salmonella infection by up-regulating IL-6 production through ERK and NF-κB but not P38 MAPK, JNK or PI3K/Akt signal pathways.

  1. Inhibitory Effects of Chung Hun Wha Dam Tang (CHWDT) on High-Fat Diet-Induced Obesity via AMP-Activated Protein Kinase Activation.

    Science.gov (United States)

    Uddin, Md Jamal; Joe, Yeonsoo; Zheng, Min; Kim, Sena; Lee, Hoyoung; Kwon, Tae-Oh; Chung, Hun Taeg

    2012-01-01

    The Chung Hun Wha Dam Tang (CHWDT) herbal combination was reported to cease dizziness and phlegm. However, the effect of CHWDT in obesity has not yet been known mechanically. Therefore, we investigated whether this CHWDT could protect the cells from lipogenesis, gluconeogenesis, and inflammation in both in vivo and in vitro. CHWDT significantly decreased body weight, epididymal and perirenal fat content without affecting feed intake in high-fat diet-induced obese mice model. Additionally, CHWDT inhibited obesity-induced SREBP1, FAS, PGC1α, G6Pase, PEPCK and increased CPT1, ACO, and LCAD genes expression in vivo and in vitro. Proinflammatory cytokines like TNF-α and iNOS expression were reduced by CHWDT in both Raw264.7 macrophages and HepG2 cells. In addition, NO production was also significantly decreased by CHWDT in LPS-stimulated macrophages. Furthermore, AMPKα activation by CHWDT was involved in inhibition of obesity by reducing triglycerides production and increasing CPT1 expression. Based on all of the results, we suggest that CHWDT has inhibitory effects on obesity-induced lipogenesis, gluconeogenesis, and inflammation via AMPKα activation.

  2. Inhibitory Effects of Chung Hun Wha Dam Tang (CHWDT on High-Fat Diet-Induced Obesity via AMP-Activated Protein Kinase Activation

    Directory of Open Access Journals (Sweden)

    Md. Jamal Uddin

    2012-01-01

    Full Text Available The Chung Hun Wha Dam Tang (CHWDT herbal combination was reported to cease dizziness and phlegm. However, the effect of CHWDT in obesity has not yet been known mechanically. Therefore, we investigated whether this CHWDT could protect the cells from lipogenesis, gluconeogenesis, and inflammation in both in vivo and in vitro. CHWDT significantly decreased body weight, epididymal and perirenal fat content without affecting feed intake in high-fat diet-induced obese mice model. Additionally, CHWDT inhibited obesity-induced SREBP1, FAS, PGC1α, G6Pase, PEPCK and increased CPT1, ACO, and LCAD genes expression in vivo and in vitro. Proinflammatory cytokines like TNF-α and iNOS expression were reduced by CHWDT in both Raw264.7 macrophages and HepG2 cells. In addition, NO production was also significantly decreased by CHWDT in LPS-stimulated macrophages. Furthermore, AMPKα activation by CHWDT was involved in inhibition of obesity by reducing triglycerides production and increasing CPT1 expression. Based on all of the results, we suggest that CHWDT has inhibitory effects on obesity-induced lipogenesis, gluconeogenesis, and inflammation via AMPKα activation.

  3. Ch’ien Chung-shu’s View of “Talent and Learning”%钱钟书论“才与学”

    Institute of Scientific and Technical Information of China (English)

    陈颖

    2015-01-01

    钱钟书在浩如烟海的古典文论话语中,独具慧眼地拈出了“才而不学”与“才须学也”这来自两极的理论言说,并以宏阔现代的眼光对这一对理论话语进行会通与创化,有效地激活并提升了“才与学”的传统文论命题,为我们探寻文学创作主体条件的深层理论奥义开拓了一条崭新的途径,为创作规律研究提供了新鲜的视角与启示。%Ch’ien Chung-shu’s found the different theories about “talent and learning” in the multitude of classical literary theory dis-courses,and he carried out discourse communication and innovation in his vision from the perspective of modern art,which effectively activated and promoted the traditional literary theory proposition about“talent and learning”, not only opening up a new way for search-ing deep theoretical meaning of literature creation conditions,but also providing new perspective and enlightenment for the study of crea-tion rules.

  4. Therapeutic Effect of Chung-Pae, an Experimental Herbal Formula, on Acute Lung Inflammation Is Associated with Suppression of NF-κB and Activation of Nrf2

    Directory of Open Access Journals (Sweden)

    Kyun Ha Kim

    2013-01-01

    Full Text Available Acute lung injury (ALI is an inflammatory disease with high mortality, but therapeutics against it is unavailable. Recently, we elaborated a formula, named Chung-pae (CP, that comprises four ethnic herbs commonly prescribed against various respiratory diseases in Asian traditional medicine. CP is being administered in aerosol to relieve various respiratory symptoms of patients in our clinic. Here, we sought to examine whether CP has a therapeutic effect on ALI and to uncover the mechanism behind it. Reporter assays show that CP suppressed the transcriptional activity of proinflammatory NF-κB and activated that of anti-inflammatory Nrf2. Similarly, CP suppressed the expression of NF-κB dependent, proinflammatory cytokines and induced that of Nrf2 dependent genes in RAW 264.7. An aerosol intratracheal administration of CP effectively reduced neutrophilic infiltration and the expression of pro-inflammatory cytokines, hallmarks of ALI, in the lungs of mice that received a prior intraperitoneal injection of lipopolysaccharide. The intratracheal CP administration concomitantly enhanced the expression of Nrf2 dependent genes in the lung. Therefore, our results evidenced a therapeutic effect of CP on ALI, in which differential regulation of the two key inflammatory factors, NF-κB and Nrf2, was involved. We propose that CP can be a new therapeutic formula against ALI.

  5. Kajian Yuridis terhadap S.E Dirjen Pajak No. 3 / P.J / 2011 tentang Pajak Penghasilan Atas Penghasilan Berupa Royalti dan Perbelakuan Pajak Pertambahan Nilai Atas Pemasukan Film Impor di Indonesia

    Directory of Open Access Journals (Sweden)

    Gusminarti Gusminarti

    2012-04-01

    Juridical Study Towards the Circular of General Directorate of Taxation Department No. 3P.J/2011 regarding Income Tax of The Royalty Income and The Aplication of Additional Tax Value of Imported Film in Indonesia

  6. MA-verpakking : oude techniek, nieuwe toepassing

    NARCIS (Netherlands)

    Stijger, H.; Boogaard, van den G.J.P.M.

    2004-01-01

    Toepassing van MA-verpakking (Modified Atmosphere) bij houtig kleinfruit. Bij MA-verpakking wordt het product in een speciale MA-folie ingepakt, het zogenoemde flowpacken, en al dan niet begast, zodat kwetsbare producten langer in goede conditie blijven

  7. Scaling of X pinches from 1 MA to 6 MA.

    Energy Technology Data Exchange (ETDEWEB)

    Bland, Simon Nicholas (Imperial College, London, United Kingdom); McBride, Ryan D.; Wenger, David Franklin; Sinars, Daniel Brian; Chittenden, Jeremy Paul (imperial College, London, United Kingdom); Pikuz, Sergei A. (Cornell University, Ithaca, NY); Harding, Eric; Jennings, Christopher A.; Ampleford, David J.; Yu, Edmund P.; Cuneo, Michael Edward; Shelkovenko, Tatiana A. (Cornell University, Ithaca, NY); Hansen, Stephanie B.

    2010-09-01

    This final report for Project 117863 summarizes progress made toward understanding how X-pinch load designs scale to high currents. The X-pinch load geometry was conceived in 1982 as a method to study the formation and properties of bright x-ray spots in z-pinch plasmas. X-pinch plasmas driven by 0.2 MA currents were found to have source sizes of 1 micron, temperatures >1 keV, lifetimes of 10-100 ps, and densities >0.1 times solid density. These conditions are believed to result from the direct magnetic compression of matter. Physical models that capture the behavior of 0.2 MA X pinches predict more extreme parameters at currents >1 MA. This project developed load designs for up to 6 MA on the SATURN facility and attempted to measure the resulting plasma parameters. Source sizes of 5-8 microns were observed in some cases along with evidence for high temperatures (several keV) and short time durations (<500 ps).

  8. Transition from potassic to sodic volcanism at ~12 Ma in the south-north striking graben: cessation of break-off and extension in south Tibet?

    Science.gov (United States)

    Xu, J.; Zhao, W.; Chen, J.; Wang, B.; Kang, Z.; Li, J.

    2008-12-01

    It has been recognized that ultra-potassic and potassic igneous rocks were dominant from 13 to 25 Ma in south Tibet, which is generally interpreted that break-off of the northward subducted Indian lithosphere or delamination of the thickened lithosphere resulted in eruption (or intrusion) of these ultra-potassic and potassic magmas (Miller et al., 1999; Maheo et al., 2002; Williams et al., 2001; Chung et al., 2005), as well as occurrence of the N-S striking extension faults ( at least before 13.5-14 Ma) on the Tibetan plateau (Coleman and Hodges, 1995; Blisniuk et al., 2001) and main elevation of the plateau in this period (e.g., 13- 18 Ma). Here we firstly report post-collisional Na-rich peralkaline volcanic rocks erupted at 12.3 (0.5) Ma within a south-north striking graben in south Tibet. These Na-rich rocks are phonolites with actual nepheline and aegirine-pyroxene minerals and significantly high Na2O/K2O ratios (higher than 1). Os-Nd isotopic and elemental compositions coupled with mineral composition analyses reveal that the Na-rich volcanic rocks cannot be generated by differentiation of the associated potassic or ultra-potassic magma; instead they were derived from a mantle source distinct from that of the latter, hinting that the mantle-derived volcanism in south Tibet experienced a temporary composition variation from potassic to sodic at about 12 Ma. Moreover, some Na-rich volcanic rocks erupted in 10-12 Ma were also found in eastern part of the Lhasa block in south Tibet. Furthermore, it has not been observed for a mantle-derived igneous rock younger than 10 Ma in south Tibet (Chung et al., 2005). Therefore, the observed transition from dominantly potassic to Na-rich magmatism represents an important tectonic event in south Tibet. We suggest that transition at about 12 Ma most possibly implies end of the break-off or delamination event, as well as temporary cession of E-W striking extension and the related uplifting process on the plateau. Thus, the

  9. Detection of O(3P(J)) atoms formed by reaction, Al+O2--> AlO+O under crossed-beam condition.

    Science.gov (United States)

    Ishida, Masayuki; Higashiyama, Tomohiko; Matsumoto, Yoshiteru; Honma, Kenji

    2005-05-22

    The vacuum ultraviolet laser-induced fluorescence technique was employed to detect the oxygen atoms formed by the reaction, Al+O(2)--> AlO+O. The measurements were carried out under the crossed-beam condition at 12.2 kJmol of collision energy. The relative populations of three spin-orbit states of O((3)P(J)) were determined to be 3.8, 1.0, and 0.2 for J=2, 1, and 0, respectively. They show nonstatistical populations, i.e., more population in O((3)P(2)) and less population in O((3)P(0)) than the statistical expectation. These populations were almost identical for two Al beam conditions where the relative concentrations of two spin-orbit states of Al, (2)P(1/2), and (2)P(3/2), are different. These results suggest that the reaction of Al with O(2) proceeds via an intermediate complex where the memory of the initial spin-orbit state is lost. Deviation from the statistical population of O((3)P(J)) implies the occurrence of the interaction among potential surfaces in the exit channel.

  10. The Inner Convergence of Tung Chung-shu and Wang Chung's Heaven Theory%论董仲舒、王充天论思想的内在趋同

    Institute of Scientific and Technical Information of China (English)

    王先亮

    2011-01-01

    "天"是中国哲学的核心概念之一,早期对"天"的理解主要集中在神灵、道德、自然之天三个层面。董仲舒视"天"为"百神之君",肯定"天"的至上神地位;王充提出"天者百神主也",视"天"为众神主宰。二者共同认定神灵之天相对于天地间一切的主宰地位。董仲舒认为人在受命于天的同时也从"天"那里获得仁德,现实政治层面的有关制度设计也取之于天;王充认为道德仁义是天道应有之义,人应戒慎恐惧、依仁义道德行事。他们共同肯定了道德之天的合理存在,并以此为人间政治、道德秩序的确立奠定坚实的基础。董仲舒认为自然运动具体展开为阴阳、四时、五行之气的流行,自然意义上天道的实际内容展现为阴阳、四时、五行的规律变化;王充认为"气"是天地的存在形态,天道运行亦即气化流行自然无为,风雨雷电等现象是阴阳之气自然流行的结果。二者对自然之天的观察共同着眼于阴阳气的大化流行。%Heaven is one of the core concepts of Chinese philosophy.The early understanding about heaven is mainly concentrated on three levels: God,moral and nature.Tung Chung-shu took heaven as the king of all Gods,and said that heaven is in the position of the supreme god.Wang Chung proposed that "heaven is the master of the Gods".Both of them believe the dominating position of God relative to every other thing in the nature;Tung Chung-shu thought that when human beings were ruled by God,they got kindheartedness from heaven,and the political system in reality was got from heaven too.Wang Chung thought morals and righteousness is embodied in the heaven itself,human should warn against fear,and act in accordance with morality.They affirmed commonly that moral exists reasonably,and then established a solid foundation for the political and moral order of the society;Tung Chung-shu thought natural movement

  11. Cinéma / Canada

    OpenAIRE

    Berthomé, Jean-Pierre; Coulombe, Michel; Dvorak, Marta; Garel, Sylvain; Noguez, Dominique; Suchet, Simone; Vimenet, Pascal

    2013-01-01

    Longtemps connue en France par le biais de cinéastes québécois tels que Claude Jutra, Gilles Carle, ou Pierre Perrault, l'industrie cinématographique du Canada a dû se développer dans l'ombre d'Hollywood. Elle s'est forgée une réputation internationale d'excellence dans les domaines qui ne concurrençaient pas les studios américains : le documentaire, le court-métrage, et les films d'animation. Nous sommes en présence d'un cinéma fortement subventionné (et même d'un cinéma d'État) qui repose s...

  12. BaMa / Raivo Juurak

    Index Scriptorium Estoniae

    Juurak, Raivo, 1949-

    2002-01-01

    Eesti ülikoolide üleminekust 3+2 süsteemile. Lühend BaMa on tulnud kasutusele seoses Euroopa ülikoolide õppekavade reformimisega ning tähistab õppekava, kus esimese astme läbimise järel omandatakse bakalaureuse- ja teise järel magistrikraad. Õppekavade tüüpidest Eesti ja Euroopa Liidu kõrgkoolides ning Bologna deklaratsioonist

  13. Roseitalea porphyridii gen. nov., sp. nov., isolated from a red alga, and reclassification of Hoeflea suaedae Chung et al. 2013 as Pseudohoeflea suaedae gen. nov., comb. nov.

    Science.gov (United States)

    Hyeon, Jong Woo; Jeong, Sang Eun; Baek, Kyunghwa; Jeon, Che Ok

    2017-02-01

    A Gram-staining-negative, strictly aerobic bacterial strain, designated MA7-20T, was isolated from a marine alga, Porphyridium marinum, in Korea. Cells showing oxidase-positive and catalase-positive activities were motile rods with bipolar flagella. Growth of strain MA7-20T was observed at 15-45 °C (optimum, 30-37 °C), at pH 6.0-10.5 (optimum, pH 7.0-8.0) and in the presence of 0-7 % (w/v) NaCl (optimum, 2-3 %). Strain MA7-20T contained summed feature 8 (comprising C18 : 1ω7c/C18 : 1ω6c), 11-methyl C18 : 1ω7c and C18 : 0 as the major fatty acids and ubiquinone-10 as the sole isoprenoid quinone. The major polar lipids were phosphatidylcholine, phosphatidylglycerol, diphosphatidylglycerol, phosphatidylethanolamine and phosphatidyl-N-methylethanolamine. The G+C content of the genomic DNA was 61.5 mol%. Strain MA7-20T was most closely related to Hoeflea suaedae YC6898T, Oricola cellulosilytica CC-AMH-0T and Nitratireductor basaltis J3T with 96.0, 95.8 and 95.8 % 16S rRNA gene sequence similarities, respectively, but the strain formed a distinct phylogenetic lineage from them within the family Phyllobacteriaceae with a low bootstrap value. H. suaedae also formed a clearly distinct phylogenetic lineage from other members of the genus Hoeflea and closely related genera. On the basis of phenotypic, chemotaxonomic and molecular properties, strain MA7-20T represents a novel species of a new genus of the family Phyllobacteriaceae, for which the name Roseitalea porphyridii gen. nov., sp. nov. is proposed. The type strain is MA7-20T (=KACC 18807T=JCM 31538T). In addition, H. suaedae is also reclassified as Pseudohoeflea suaedae gen. nov., comb. nov. (type strain YC6898T=KACC 14911T=NBRC 107700T).

  14. On the Characteristics and the Value of Ch’ ien Chung-shu’ s Literary Criticism%钱锺书文学批评话语的特征与意义

    Institute of Scientific and Technical Information of China (English)

    周雅春

    2014-01-01

    钱锺书的文学批评在“说什么”和“怎么说”上自有一套与众不同的话语系统,梳理这套话语系统的特点,揭示其中隐含的文学研究的观念、维度、取向、策略与方法,正是《钱锺书文学批评话语研究》一书达成的主要目的。%There is a discourse system in Ch ’ ien Chung -shu ’ s Literary Criticism in regard to “discussing what” and “How to disscuss”.Therefore , evealing the characteristics of this discourse system and his academic concepts, dimensions, interest and strategic approach is exactly the purpose of that book which named “Study on the Characteristics of Ch ’ ien Chung-shu’ s Literary Criticism Discourse”.

  15. Respons op Die dood van die outeur en die inspirasie van die Bybel: in gesprek met P.J. Nel en S.D. Snyman

    Directory of Open Access Journals (Sweden)

    S. D. (Fanie Snyman

    2006-07-01

    Full Text Available Response to The death of the author and the inspiration of the Bible: in discussion with P.J. Nel and S.D. Snyman This contribution is a response to an article that enters into a debate with an earlier article by the present author published in 2003, where it was argued that current theories on the inspiration of the Bible can no longer be maintained due to our knowledge of the origin of especially the Old Testament. In this response it is argued that the arguments put forward as a critique of the earlier article are not convincing. Arguments against current theories of the inspiration of the Bible are taken note of, but they are not countered for. Furthermore, some of the arguments are simply ignored. The status quo seems to be the answer proposed.

  16. CT fluoroscopy guided percutaneous gastrostomy or jejunostomy without (CT-PG/PJ) or with simultaneous endoscopy (CT-PEG/PEJ) in otherwise untreatable patients.

    Science.gov (United States)

    Spelsberg, Fritz W; Hoffmann, Ralf-Thorsten; Lang, Reinhold A; Winter, Hauke; Weidenhagen, Rolf; Reiser, Maximilian; Jauch, Karl-Walter; Trumm, Christoph

    2013-04-01

    Percutaneous endoscopic gastrostomy (PEG) or percutaneous endoscopic jejunostomy (PEJ) are substantial for patients with swallowing disorders to maintain enteral nutrition or to decompress palliatively intractable small bowel obstruction. Endoscopic placement can be impossible due to previous (gastric) operation, obesity, hepato-splenomegaly, peritoneal carcinosis, inadequate transillumination, or obstructed passage. Computed tomography (CT)-fluoroscopic guidance with or without endoscopy can enable placement of CT-PG/CT-PJ or CT-PEG/CT-PEJ if endoscopically guided placement fails. In this retrospective study, we will evaluate the feasibility and safety of this method. A total of 101 consecutive patients were referred to our department for feeding support (n = 87) or decompression (n = 14). Reasons were: ENT tumor (n = 51), esophageal cancer (n = 19), mediastinal mass (n = 2), neurological disorder (n = 15). Decompression tubes were placed because of cancer (n = 13) or Crohn's disease (n = 1). The following approaches were chosen: CT fluoroscopy and simultaneous gastroscopy (n = 61), inflation of the stomach via nasogastric tube (n = 29), and direct puncture under CT-fluoroscopic guidance (n = 11). CT fluoroscopy-guided gastrostomy was feasible in 89 of 101 patients. No procedure-related mortality was observed. One tube was misplaced into the colon in a patient with a history of gastrectomy. No complication was seen after removal. Minor complications: dislodgement (n = 17), peristomal leakage (n = 7), wound infection (n = 1), superficial skin infection (n = 6), tube obstruction (n = 2). CT fluoroscopy-guided PG/PJ or PEG/PEJ is feasible and safe and provides adequate feeding support or decompression. It offers the benefits of minimally invasive therapy even in patients with contraindications to established endoscopic methods, combining the advantages of both techniques. Long-term complications-mainly tube-related problems-are easily treated.

  17. 33 CFR 80.125 - Marblehead Neck, MA to Nahant, MA.

    Science.gov (United States)

    2010-07-01

    ... 33 Navigation and Navigable Waters 1 2010-07-01 2010-07-01 false Marblehead Neck, MA to Nahant, MA... INTERNATIONAL NAVIGATION RULES COLREGS DEMARCATION LINES Atlantic Coast § 80.125 Marblehead Neck, MA to Nahant, MA. The 72 COLREGS apply on the harbors, bays, and inlets on the east coast of Massachusetts...

  18. 33 CFR 80.135 - Hull, MA to Race Point, MA.

    Science.gov (United States)

    2010-07-01

    ... 33 Navigation and Navigable Waters 1 2010-07-01 2010-07-01 false Hull, MA to Race Point, MA. 80.135 Section 80.135 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY INTERNATIONAL NAVIGATION RULES COLREGS DEMARCATION LINES Atlantic Coast § 80.135 Hull, MA to Race Point, MA....

  19. Chung Hwa Industrial Magazine's thoughts of saving the nation by engaging in industry%《中华实业界》实业救国思想的传播初探

    Institute of Scientific and Technical Information of China (English)

    徐跃; 姚远

    2012-01-01

    Aim To study Chung Hwa Industrial Magazine's ideas about the reason why Chinese industry was weak and provide new Citeratare basis for the history of scientific thought in China. Methods The original journal literature analysis and textual research method. Results Chung Hwa Industrial Magazine introduced the following disadvantages of Chinese industry; disadvantages about the government; about the education; about the organization itself; about the managing science and about the society. The personal training of managers can be seen as another acting factor. Conclusion Chung Hwa Industrial Magazine mainly aimed at the thoughts of saving the nation through industry, through the way to find out the disadvantages exist in Chinese industry, therefore provided solutions , which was very different from the discussion in the last years of Qing Dynasty. It plays an important role in the development of the thoughts of saving the nation by engaging in industry.%目的 研究《中华实业界》所传播的实业救国思想,为中国期刊史与科学思想史提供新的文献依据.方法 采用原始期刊文献分析和考证法.结果 《中华实业界》认为中国实业不振的原因在于政府、在于教育、在于实业组织自身、在于管理法、在于社会.实业家自身的修养也与实业振兴与否休戚相关,而挽救方法也要从相应各个方面进行改革.结论 《中华实业界》从国家政治、教育、科技、实业组织法、社会环境等视角对中国实业不振原因的探索,以及提出的振兴实业之道,不同于晚清洋务派言论与维新期刊的泛泛而谈和译介模仿,而是开始深入触及体制与机制问题,标志着实业救国思想的成熟与历史性转折.

  20. Ma Ying-jeou’s Presidential Discourse

    OpenAIRE

    2012-01-01

    "Despite the substantial advances made in cross-Strait relations during Ma Ying-jeou's (Ma Yingjiu) first term, the ROC president's rhetoric varied considerably as he grappled with the difficult reality of implementing campaign and inauguration pledges to establish better relations with China while striving to maintain national respect and sovereignty. In this article, the authors put forward a framework for measuring, analyzing and explaining this variation in President Ma's first-term disco...

  1. Comparative study of multi-enzyme production from typical agro-industrial residues and ultrasound-assisted extraction of crude enzyme in fermentation with Aspergillus japonicus PJ01.

    Science.gov (United States)

    Li, Pei-jun; Xia, Jin-lan; Shan, Yang; Nie, Zhen-yuan

    2015-10-01

    Submerged fermentation (SmF) and solid-state fermentation (SSF) of Aspergillus japonicus PJ01 for multi-enzyme complexes (MEC) production were comparatively studied. The results showed that orange peel and wheat bran were the best substrates for MEC production in SmF and SSF, respectively. After 72 h of cultivation under SmF, the maximal pectinase, CMCase, and xylanase activities reached 2610, 85, and 335 U/gds (units/gram dry substrate), respectively; while after 72 h of cultivation under SSF, these three enzymes' activities reached 966, 58, and 1004 U/gds, respectively. Effects of ultrasound on extraction of crude enzymes from SSF medium were determined, the maximal activities of pectinase, CMCase, and xylanase increased to 1.20, 1.48, and 1.30-fold, respectively. Apparent different mycelia growths of SSF and SmF were observed by scanning electron microscopy; and different isoforms of the crude enzyme extracts from SSF and SmF were presented by zymogram analysis.

  2. Die dood van die outeur en die inspirasie van die Bybel: in gesprek met P.J. Nel en S.D. Snyman

    Directory of Open Access Journals (Sweden)

    P. Verster

    2005-07-01

    Full Text Available The death of the author and the inspiration of the Bible: in discussion with P.J. Nel and S.D. Snyman In the present debate on post-modernism, the question is also asked whether author’s intention can be indicated in a specific text. Nel (2003 and Snyman (2003 refer to this debate. Nel questions the view that author’s intention can be indicated in the Bible as text and especially doubts whether the view that God can be called the primary author of the Bible is still acceptable. Snyman suggests that present theories of inspiration should be expanded, since the history of the Bible’s origin is not adequately addressed in these theories. The concept of author’s intention should, however, not necessarily be disregarded, and the organic (personal inspiration theory still offers the opportunity to explain the multifaceted aspects of the Bible. Presuppositions, however, play an important role in the views taken.

  3. M&A Negotiations and Lawyer Expertise

    NARCIS (Netherlands)

    Karsten, C.; Malmendier, U.; Sautner, Z.

    2013-01-01

    We use proprietary data to look into the "black box" of M&A negotiations and to shed light on the effects of lawyer expertise on M&A contract design, the bargaining process, and acquisition pricing. Measuring the effects of buyer relative to seller lawyer expertise, we document that more expertise i

  4. 33 CFR 80.120 - Cape Ann, MA to Marblehead Neck, MA.

    Science.gov (United States)

    2010-07-01

    ... 33 Navigation and Navigable Waters 1 2010-07-01 2010-07-01 false Cape Ann, MA to Marblehead Neck, MA. 80.120 Section 80.120 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY INTERNATIONAL NAVIGATION RULES COLREGS DEMARCATION LINES Atlantic Coast § 80.120 Cape Ann, MA...

  5. The effect of collisional quenching of the O 3p 3PJ state on the determination of the spatial distribution of the atomic oxygen density in an APPJ operating in ambient air by TALIF

    Science.gov (United States)

    Zhang, S.; van Gessel, A. F. H.; van Grootel, S. C.; Bruggeman, P. J.

    2014-04-01

    The spatial profile of the absolute atomic oxygen density is obtained by two-photon absorption laser-induced fluorescence (TALIF) in an Ar+2% air cold atmospheric pressure plasma jet (APPJ) operating in ambient air. The varying air concentration in the jet effluent which contributes to the collisional quenching of the O 3p 3PJ state, pumped by the laser, strongly influences the recorded TALIF signal under the present experimental conditions. The spatially resolved air densities obtained from Raman scattering measurements have been reported in our previous work (van Gessel et al 2013 Appl. Phys. Lett. 103 064103). These densities allow us to calculate the spatially dependent collisional quenching rate for the O 3p 3PJ state and reconstruct the spatial O density profile from the recorded TALIF signal. Significant differences between the TALIF intensity profile and the actual O density profile for the investigated experimental conditions are found.

  6. Susceptibility of Inbred Mice to Leishmania major Infection: Genetic Analysis of Macrophage Activation and Innate Resistance to Disease in Individual Progeny of P/J (Susceptible) and C3H/HeN (Resistant) Mice

    Science.gov (United States)

    1990-12-01

    mediated immu- ease and defective macrophage activation in Bx mice that nity in mice highly susceptible to Leishmania tropica . J. Exp. could not be...inbred mice to Leishmania tropica infec- tion: correlation of susceptibility with in vitro defective macro- LITERATURE CITED phage microbicidal...probability and phage activation to kill Leishmania tropica : characterization of statistics. Chemical Rubber Co., Cleveland. P/J mouse macrophage defects for

  7. HTP kinetics studies of the reactions of O(2 3PJ) atoms with H2 and D2 over wide temperature ranges

    Science.gov (United States)

    Marshall, Paul; Fontijn, Arthur

    1987-12-01

    The O+H2(1) and O+D2(2) reactions have been investigated, using the high-temperature photochemistry (HTP) technique, over the 350 to 1420 and 390 to 1420 K temperature ranges, respectively. O(2 3PJ) atoms were generated from flash photolysis of CO2 and monitored by time-resolved atomic resonance fluorescence with pulse counting. Above 430 K the rate coefficients are given by k1(T)=7.3×10-21 (T/K)2.93 exp(-2980 K/T) cm3 molecule-1 s-1 and k2(T)=3.1×10-16 (T/K)1.65 exp (-5260 K/T) cm3 molecule-1 s-1. Combination of our data with those from other experiments which isolated the reactions from secondary processes yields our recommendations k1(T)=1.5×10-12 exp (-3540 K/T)+3.7×10-10 exp (-7450 K/T) cm3 molecule-1 s-1 (300 K≤T≤2500 K) and k2(T)=1.4×10-12 exp(-4260 K/T) +2.9×10-10 exp (-7780 K/T) cm3 molecule-1 s-1 (390 K≤T≤1420 K). Accuracy assessments are discussed in the text. k1(T), k2(T), and the kinetic isotope effect compare well with calculations based on recent ICVT/LAG and CEQB ab initio methods, which suggest that the first terms of the double exponential expressions approximate the tunneling contributions.

  8. Ma olin Saddami poeg / Latif Jahija

    Index Scriptorium Estoniae

    Jahija, Latif

    1995-01-01

    Järg Jan/21.,28. lk. 7,5. L. Jahija sensatsiooniline raamat "Ma olin Saddami poeg", milles ta pajatab kuidas ta a. 1987-1991 oli Iraagi presidendi vanema poja teisik. Lühikokkuvõte sellest jutustusest

  9. Morfologia do sincrânio do boto-cinza, Sotalia guianensis (P.J. van Bénéden (Cetacea, Delphinidae Syncranial morphology of the estuarine dolphin Sotalia guianensis (P.J. van Bénéden (Cetacea, Delphinidae

    Directory of Open Access Journals (Sweden)

    Paulo C. Simões-Lopes

    2006-09-01

    Full Text Available Apresenta-se uma descrição da morfologia comparada do sincrânio de Sotalia guianensis (P.J. van Bénéden, 1864, incluindo suas variações ontogenéticas e intra-específicas. As descrições foram baseadas em 51 crânios completos ou parciais depositados na coleção do laboratório de Mamíferos Aquáticos, do Departamento de Ecologia e Zoologia, CCB, Universidade Federal de Santa Catarina. O sincrânio é bastante homogêneo e manifesta sua assimetria na morfologia dos ossos, passagens nasais e forames. O rostro é proporcionalmente estreito em relação aos outros Delphinidae do mesmo porte. A região temporal é circular em indivíduos jovens, mas se torna oval nos adultos onde se forma uma crista temporal evidente. O forame elíptico do periótico está presente tanto em indivíduos jovens quanto adultos. Os nasais são bipartidos e podem ocorrer ossos suturais entre os frontais. O processo hamular dos pterigóides é bastante inflado e fenestrado. A sínfise mandibular alcança de 19 de 19-23% do comprimento do dentário. Cada pré-maxilar e maxilar possui de 30-35 dentes e cada dentário de 30-38 dentes.Morphological and comparative description of the syncranium of Sotalia guianensis (P.J. van Bénéden, 1864, including ontogenic aspects and intraspecific variations are presented. The descriptions were based on the examination of 51 complete or partial skulls, kept at the Marine Mammals Lab. Collection from the Departamento de Ecologia e Zoologia, CCB, at the Federal University of Santa Catarina. The sincranium is very homogeneous and manifests its asymmetry in the morphology of the bones, nasal passages and foramina. The rostrum is proportionally narrow in relation to other Delphinidae of the same size. The temporal region is circular in young specimens, but it becomes oval in the adults were it forms a well marked temporal crest. The elliptical foramen of the periotic bone is present both in young and adult individuals. The nasals

  10. MaRIE Undulator & XFEL Systems

    Energy Technology Data Exchange (ETDEWEB)

    Nguyen, Dinh Cong [Los Alamos National Laboratory; Marksteiner, Quinn R. [Los Alamos National Laboratory; Anisimov, Petr Mikhaylovich [Los Alamos National Laboratory; Buechler, Cynthia Eileen [Los Alamos National Laboratory

    2015-03-23

    The 22 slides in this presentation treat the subject under the following headings: MaRIE XFEL Performance Parameters, Input Electron Beam Parameters, Undulator Design, Genesis Simulations, Risks, and Summary It is concluded that time-dependent Genesis simulations show the MaRIE XFEL can deliver the number of photons within the required bandwidth, provided a number of assumptions are met; the highest risks are associated with the electron beam driving the XFEL undulator; and risks associated with the undulator and/or distributed seeding technique may be evaluated or retired by performing early validation experiments.

  11. M&A Takeover Fever Heats Up

    Institute of Scientific and Technical Information of China (English)

    2006-01-01

    @@ China's M&A activity is in turbo-drive. Outward investment is soaring, as many more Chinese companies need and are able to pursue opportunities overseas. Inward investment is accelerating, as foreign firms seek a foothold in the potentially lucrative Chinese market. And domestic consolidation is heating up among the country's fragmented industries due to overcapacity. Now that the Chinese government plans to address policy hurdles affecting M&A and relax foreign currency controls, activity levels should rise across most sectors. But while this may improve market positions and increase synergies for local and foreign investors, credit risks could intensify.

  12. Operation and maintenance in ST-MA

    CERN Document Server

    Nunes, R

    2003-01-01

    This paper will review the Operation & Maintenance (O&M) activities in the ST-MA group, giving an overview of the services provided by the Group as well as the contract activities. As an introduction, a conceptual framework for O&M is proposed in order to better situate the domains of Operation and Maintenance respectively. The ST-MA activities shall be looked at through the three main service axes and special emphasis will be given to the contractual implementation, supervision and follow-up methodology.

  13. M&A information technology best practices

    CERN Document Server

    Roehl-Anderson, Janice M

    2013-01-01

    Add value to your organization via the mergers & acquisitions IT function  As part of Deloitte Consulting, one of the largest mergers and acquisitions (M&A) consulting practice in the world, author Janice Roehl-Anderson reveals in M&A Information Technology Best Practices how companies can effectively and efficiently address the IT aspects of mergers, acquisitions, and divestitures. Filled with best practices for implementing and maintaining systems, this book helps financial and technology executives in every field to add value to their mergers, acquisitions, and/or divestitures via the IT

  14. Salatoimikud : ma tahan uskuda / Mart Rummo

    Index Scriptorium Estoniae

    Rummo, Mart

    2008-01-01

    USA sarjale "The X-Files" põhinev teine järjefilm "Salatoimikud: Ma tahan uskuda" ("The X-Files: I Want to Believe") : režissöör Chris Carter : peaosades David Duchovny, Gillian Anderson : Ameerika Ühendriigid - Kanada 2008

  15. Maíz I (Zea mays)

    OpenAIRE

    Sánchez Ortega, Iván; Pérez-Urria Carril, Elena

    2014-01-01

    El maíz es uno de los cultivos básicos más importantes y extendidos en todo el mundo. Constituye una de las fuentes principales de alimento de millones depersonas, sobre todo en América y Asia. Se trata de una de las primeras plantas que se domesticaron y se difundieron por todo el mundo.

  16. 76 FR 36953 - Massachusetts Disaster #MA-00036

    Science.gov (United States)

    2011-06-23

    ... From the Federal Register Online via the Government Publishing Office ] SMALL BUSINESS ADMINISTRATION Massachusetts Disaster MA-00036 AGENCY: U.S. Small Business Administration. ACTION: Notice. SUMMARY: This is a Notice of the Presidential declaration of a major disaster for the State...

  17. 77 FR 76585 - Massachusetts Disaster # MA-00052

    Science.gov (United States)

    2012-12-28

    ... From the Federal Register Online via the Government Publishing Office SMALL BUSINESS ADMINISTRATION Massachusetts Disaster MA-00052 AGENCY: U.S. Small Business Administration. ACTION: Notice. SUMMARY: This is a notice of an Administrative declaration of a disaster for the Commonwealth...

  18. 77 FR 66214 - Massachusetts Disaster # MA-00049

    Science.gov (United States)

    2012-11-02

    ... From the Federal Register Online via the Government Publishing Office SMALL BUSINESS ADMINISTRATION Massachusetts Disaster MA-00049 AGENCY: U.S. Small Business Administration. ACTION: Notice. SUMMARY: This is a notice of an Administrative declaration of a disaster for the Commonwealth...

  19. 76 FR 56859 - Massachusetts Disaster #MA-00039

    Science.gov (United States)

    2011-09-14

    ... From the Federal Register Online via the Government Publishing Office SMALL BUSINESS ADMINISTRATION Massachusetts Disaster MA-00039 AGENCY: U.S. Small Business Administration. ACTION: Notice. SUMMARY: This is a Notice of the Presidential declaration of a major disaster for the Commonwealth...

  20. 75 FR 45681 - Massachusetts Disaster #MA-00028.

    Science.gov (United States)

    2010-08-03

    ... From the Federal Register Online via the Government Publishing Office SMALL BUSINESS ADMINISTRATION Massachusetts Disaster MA-00028. AGENCY: U.S. Small Business Administration. ACTION: Notice. SUMMARY: This is a notice of an Administrative declaration of a disaster for the Commonwealth...

  1. 75 FR 22874 - Massachusetts Disaster # MA-00027

    Science.gov (United States)

    2010-04-30

    ... From the Federal Register Online via the Government Publishing Office ] SMALL BUSINESS ADMINISTRATION Massachusetts Disaster MA-00027 AGENCY: U.S. Small Business Administration. ACTION: Notice. SUMMARY: This is a Notice of the Presidential declaration of a major disaster for Public Assistance...

  2. 76 FR 56853 - Massachusetts Disaster #MA-00040

    Science.gov (United States)

    2011-09-14

    ... From the Federal Register Online via the Government Publishing Office SMALL BUSINESS ADMINISTRATION Massachusetts Disaster MA-00040 AGENCY: U.S. Small Business Administration. ACTION: Notice. SUMMARY: This is a Notice of the Presidential declaration of a major disaster for Public Assistance...

  3. Teacher MA Attainment Rates, 1970-2000

    Science.gov (United States)

    Larsen, S. Eric

    2010-01-01

    The share of female teachers in the U.S. with an MA more than doubled between 1970 and 2000. This increase is puzzling, as it is much larger than that of other college-educated women, and it occurred over a period of declining teacher aptitude. I estimate the contribution of changes in teacher demographic characteristics, increases in the returns…

  4. 76 FR 65557 - Massachusetts Disaster #MA-00043

    Science.gov (United States)

    2011-10-21

    ... From the Federal Register Online via the Government Publishing Office SMALL BUSINESS ADMINISTRATION Massachusetts Disaster MA-00043 AGENCY: U.S. Small Business Administration. ACTION: Notice. SUMMARY: This is a notice of an Administrative declaration of a disaster for the Commonwealth...

  5. 75 FR 17177 - Massachusetts Disaster #MA-00025

    Science.gov (United States)

    2010-04-05

    ... From the Federal Register Online via the Government Publishing Office SMALL BUSINESS ADMINISTRATION Massachusetts Disaster MA-00025 AGENCY: U.S. Small Business Administration. ACTION: Notice. SUMMARY: This is a Notice of the Presidential declaration of a major disaster for the State...

  6. 76 FR 36952 - Massachusetts Disaster #MA-00037

    Science.gov (United States)

    2011-06-23

    ... From the Federal Register Online via the Government Publishing Office SMALL BUSINESS ADMINISTRATION Massachusetts Disaster MA-00037 AGENCY: U.S. Small Business Administration. ACTION: Notice. SUMMARY: This is a Notice of the Presidential declaration of a major disaster for Public Assistance...

  7. 77 FR 76584 - Massachusetts Disaster # MA-00051

    Science.gov (United States)

    2012-12-28

    ... From the Federal Register Online via the Government Publishing Office SMALL BUSINESS ADMINISTRATION Massachusetts Disaster MA-00051 AGENCY: U.S. Small Business Administration. ACTION: Notice. SUMMARY: This is a notice of an Administrative declaration of a disaster for the Commonwealth...

  8. 77 FR 2600 - Massachusetts Disaster #MA-00046

    Science.gov (United States)

    2012-01-18

    ... From the Federal Register Online via the Government Publishing Office SMALL BUSINESS ADMINISTRATION Massachusetts Disaster MA-00046 AGENCY: U.S. Small Business Administration. ACTION: Notice. SUMMARY: This is a Notice of the Presidential declaration of a major disaster for Public Assistance...

  9. 76 FR 13697 - Massachusetts Disaster #MA-00032

    Science.gov (United States)

    2011-03-14

    ... From the Federal Register Online via the Government Publishing Office SMALL BUSINESS ADMINISTRATION Massachusetts Disaster MA-00032 AGENCY: U.S. Small Business Administration. ACTION: Notice. SUMMARY: This is a Notice of the Presidential declaration of a major disaster for Public Assistance...

  10. 78 FR 2708 - Massachusetts Disaster # MA-00050

    Science.gov (United States)

    2013-01-14

    ... ADMINISTRATION Massachusetts Disaster MA-00050 AGENCY: U.S. Small Business Administration. ACTION: Notice... completed loan applications to: U.S. Small Business Administration, Processing and Disbursement Center... Disaster Assistance, U.S. Small Business Administration, 409 3rd Street SW., Suite 6050, Washington,...

  11. 78 FR 25336 - Massachusetts Disaster #MA-00054

    Science.gov (United States)

    2013-04-30

    ... ADMINISTRATION Massachusetts Disaster MA-00054 AGENCY: U.S. Small Business Administration. ACTION: Notice...: 01/21/2014. ADDRESSES: Submit completed loan applications to: U.S. Small Business Administration... CONTACT: A. Escobar, Office of Disaster Assistance, U.S. Small Business Administration, 409 3rd Street...

  12. Fabrication technology for ODS Alloy MA957

    Energy Technology Data Exchange (ETDEWEB)

    ML Hamilton; DS Gelles; RJ Lobsinger; MM Paxton; WF Brown

    2000-03-16

    A successful fabrication schedule has been developed at Carpenter Technology Corporation for the production of MA957 fuel and blanket cladding. Difficulties with gun drilling, plug drawing and recrystallization were overcome to produce a pilot lot of tubing. This report documents the fabrication efforts of two qualified vendors and the support studies performed at WHC to develop the fabrication-schedule.

  13. Vaccines against stimulants: cocaine and MA.

    Science.gov (United States)

    Kosten, Thomas; Domingo, Coreen; Orson, Frank; Kinsey, Berma

    2014-02-01

    While the worldwide prevalence of cocaine use remains significant, medications, or small molecule approaches, to treat drug addictions have met with limited success. Anti-addiction vaccines, on the other hand, have demonstrated great potential for treating drug abuse using a distinctly different mechanism of eliciting an antibody response that blocks the pharmacological effects of drugs. We provide a review of vaccine-based approaches to treating stimulant addictions; specifically and cocaine addictions. This selective review article focuses on the one cocaine vaccine that has been into clinical trials and presents new data related to pre-clinical development of a methamphetamine (MA) vaccine. We also review the mechanism of action for vaccine induced antibodies to abused drugs, which involves kinetic slowing of brain entry as well as simple blocking properties. We present pre-clinical innovations for MA vaccines including hapten design, linkage to carrier proteins and new adjuvants beyond alum. We provide some new information on hapten structures and linkers and variations in protein carriers. We consider a carrier, outer membrance polysaccharide coat protein (OMPC), that provides some self-adjuvant through lipopolysaccharide components and provide new results with a monophosopholipid adjuvant for the more standard carrier proteins with cocaine and MA. The review then covers the clinical trials with the cocaine vaccine TA-CD. The clinical prospects for advances in this field over the next few years include a multi-site cocaine vaccine clinical trial to be reported in 2013 and phase 1 clinical trials of a MA vaccine in 2014.

  14. Salatoimikud : ma tahan uskuda / Mart Rummo

    Index Scriptorium Estoniae

    Rummo, Mart

    2008-01-01

    USA sarjale "The X-Files" põhinev teine järjefilm "Salatoimikud: Ma tahan uskuda" ("The X-Files: I Want to Believe") : režissöör Chris Carter : peaosades David Duchovny, Gillian Anderson : Ameerika Ühendriigid - Kanada 2008

  15. Global Plate Driving Forces at 50Ma

    Science.gov (United States)

    Butterworth, N. P.; Quevedo, L. E.; Müller, R. D.

    2011-12-01

    We apply a novel workflow utilising the BEM-Earth geodynamic software to analyse the global coupled plate-mantle dynamics at 50 Ma. A subduction history model based on kinematic data going as far back as 80 Ma was developed using the GPlates software. Advection of the plates into the mantle takes into account the absolute plate motions and lithospheric thickness derived from its age to produce an estimated density heterogeneity initial model condition in the upper mantle. The resulting global model consists of regions of a mantle viscosity and density structure that is post-processed to ensure smooth non-overlapping 3D surfaces. BEM-Earth is then free to evolve the model toward the 50 Ma solution. The evolution of the model is driven by self-consistent buoyancy driven mantle dynamics. We use the model velocity output to quantify changes in forces driving the plates before and after 50 Ma. We analyse the rapid change in plate motion of India, Africa and plates in the Pacific Ocean basin by considering slab-pull, ridge-push and mantle drag/suction forces that naturally result from such top-down driven mantle flow. We compare the results with plate kinematic reconstructions and other geological observations.

  16. 77 FR 33263 - Massachusetts Disaster #MA-00048

    Science.gov (United States)

    2012-06-05

    ... ADMINISTRATION Massachusetts Disaster MA-00048 AGENCY: U.S. Small Business Administration. ACTION: Notice. SUMMARY: This is a notice of an Administrative declaration of a disaster for the Commonwealth of Massachusetts dated 05/29/2012. Incident: Lake Williams Condominium Complex Fire. Incident Period:...

  17. 76 FR 30748 - Massachusetts Disaster #MA-00033

    Science.gov (United States)

    2011-05-26

    ... ADMINISTRATION Massachusetts Disaster MA-00033 AGENCY: U.S. Small Business Administration. ACTION: Notice. SUMMARY: This is a notice of an Administrative declaration of a disaster for the Commonwealth of Massachusetts dated 05/19/2011. Incident: Apartment Building Fire. Incident Period: 04/30/2011. Effective...

  18. 75 FR 79064 - Massachusetts Disaster #MA-00030

    Science.gov (United States)

    2010-12-17

    ... ADMINISTRATION Massachusetts Disaster MA-00030 AGENCY: U.S. Small Business Administration. ACTION: Notice. SUMMARY: This is a notice of an Administrative declaration of a disaster for the Commonwealth of Massachusetts dated 12/07/2010. Incident: Apartment complex fire. Incident Period: 11/21/2010. Effective...

  19. 76 FR 40766 - Massachusetts Disaster #MA-00035

    Science.gov (United States)

    2011-07-11

    ... ADMINISTRATION Massachusetts Disaster MA-00035 AGENCY: U.S. Small Business Administration. ACTION: Notice. SUMMARY: This is a notice of an Administrative declaration of a disaster for the Commonwealth of Massachusetts dated 06/29/2011. Incident: Johnsonia Apartment Building Fire Incident Period:...

  20. 77 FR 12350 - Massachusetts Disaster #MA-00047

    Science.gov (United States)

    2012-02-29

    ... ADMINISTRATION Massachusetts Disaster MA-00047 AGENCY: U.S. Small Business Administration. ACTION: Notice. SUMMARY: This is a notice of an Administrative declaration of a disaster for the Commonwealth of Massachusetts dated 02/21/2012. Incident: Brookline Apartment Building Fire. Incident Period:...

  1. 75 FR 3764 - Massachusetts Disaster # MA-00024

    Science.gov (United States)

    2010-01-22

    ... ADMINISTRATION Massachusetts Disaster MA-00024 AGENCY: U.S. Small Business Administration. ACTION: Notice. SUMMARY: This is a notice of an Administrative declaration of a disaster for the Commonwealth of Massachusetts dated 01/15/2010. Incident: Mystic Side Estates Apartment Building Fire. Incident Period:...

  2. 46 CFR 308.550 - Certificate, Form MA-320.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 8 2010-10-01 2010-10-01 false Certificate, Form MA-320. 308.550 Section 308.550... Risk Cargo Insurance Iv-General § 308.550 Certificate, Form MA-320. Wherever any provision of this... execute a certificate on Form MA-320-A for an individual, on Form MA-320-B for a partnership, or on...

  3. 42 CFR 422.4 - Types of MA plans.

    Science.gov (United States)

    2010-10-01

    ... 42 Public Health 3 2010-10-01 2010-10-01 false Types of MA plans. 422.4 Section 422.4 Public...) MEDICARE PROGRAM MEDICARE ADVANTAGE PROGRAM General Provisions § 422.4 Types of MA plans. (a) General rule. An MA plan may be a coordinated care plan, a combination of an MA MSA plan and a contribution into...

  4. Mañana remisión de V. crepúsculo de la mañana.

    OpenAIRE

    2011-01-01

    [ES] Definición del término Mañana remisión de V. crepúsculo de la mañana. en el diccionario Dicter. [EN] Definition of the word Mañana remisión de V. crepúsculo de la mañana. in the dictionary Dicter.

  5. MaJAZ1 Attenuates the MaLBD5-Mediated Transcriptional Activation of Jasmonate Biosynthesis Gene MaAOC2 in Regulating Cold Tolerance of Banana Fruit.

    Science.gov (United States)

    Ba, Liang-jie; Kuang, Jian-fei; Chen, Jian-ye; Lu, Wang-jin

    2016-02-01

    Previous studies indicated that methyl jasmonate (MeJA) treatment could effectively reduce the chilling injury of many fruits, including banana, but the underlying mechanism is poorly understood. In this study, one lateral organ boundaries (LOB) domain (LBD) gene, designated as MaLBD5, was isolated and characterized from banana fruit. Expression analysis revealed that accumulation of MaLBD5 was induced by cold temperature and MeJA treatment. Subcellular localization and transactivation assays showed that MaLBD5 was localized to the nucleus and possessed transcriptional activation activity. Protein-protein interaction analysis demonstrated that MaLBD5 physically interacted with MaJAZ1, a potential repressor of jasmonate signaling. Furthermore, transient expression assays indicated that MaLBD5 transactivated a jasmonate biosynthesis gene, termed MaAOC2, which was also induced by cold and MeJA. More interestingly, MaJAZ1 attenuated the MaLBD5-mediated transactivation of MaAOC2. These results suggest that MaLBD5 and MaJAZ1 might act antagonistically in relation to MeJA-induced cold tolerance of banana fruit, at least partially via affecting jasmonate biosynthesis. Collectively, our findings expand the knowledge of the transcriptional regulatory network of MeJA-mediated cold tolerance of banana fruit.

  6. Mass and Reliability System (MaRS)

    Science.gov (United States)

    Barnes, Sarah

    2016-01-01

    The Safety and Mission Assurance (S&MA) Directorate is responsible for mitigating risk, providing system safety, and lowering risk for space programs from ground to space. The S&MA is divided into 4 divisions: The Space Exploration Division (NC), the International Space Station Division (NE), the Safety & Test Operations Division (NS), and the Quality and Flight Equipment Division (NT). The interns, myself and Arun Aruljothi, will be working with the Risk & Reliability Analysis Branch under the NC Division's. The mission of this division is to identify, characterize, diminish, and communicate risk by implementing an efficient and effective assurance model. The team utilizes Reliability and Maintainability (R&M) and Probabilistic Risk Assessment (PRA) to ensure decisions concerning risks are informed, vehicles are safe and reliable, and program/project requirements are realistic and realized. This project pertains to the Orion mission, so it is geared toward a long duration Human Space Flight Program(s). For space missions, payload is a critical concept; balancing what hardware can be replaced by components verse by Orbital Replacement Units (ORU) or subassemblies is key. For this effort a database was created that combines mass and reliability data, called Mass and Reliability System or MaRS. The U.S. International Space Station (ISS) components are used as reference parts in the MaRS database. Using ISS components as a platform is beneficial because of the historical context and the environment similarities to a space flight mission. MaRS uses a combination of systems: International Space Station PART for failure data, Vehicle Master Database (VMDB) for ORU & components, Maintenance & Analysis Data Set (MADS) for operation hours and other pertinent data, & Hardware History Retrieval System (HHRS) for unit weights. MaRS is populated using a Visual Basic Application. Once populated, the excel spreadsheet is comprised of information on ISS components including

  7. Cinéma en France

    Directory of Open Access Journals (Sweden)

    Michel VIGOUROUX

    1992-06-01

    Full Text Available Le cinéma est l’objet de bases de données exhaustives sur les équipements et les fréquentations. Les données sur les salles permettent d’identifier le phénomène de concentration de propriété et d’exploitation. La perspective dynamique peut être observée sur 45 ans. À l’échelle régionale, on peut apprécier le dynamisme du cinéma en haute montagne alpine et la différence de réseaux sur le territoire (France de l’Ouest.

  8. Sobre Juan Bautista Maíno

    Directory of Open Access Journals (Sweden)

    Pérez Sánchez, Alfonso E.

    1997-06-01

    Full Text Available This article published new documents about the activity of the Domenican painter Juan Bautista Maíno specially concerning his concept of the practice of Painting in relation to the other arts. Works hitherto unknown are published here for the first time. Also illustrated are portraits of the Conde de Añover de Tajo and his wife, whose collections were, in addition given valuation by the artista.No disponible

  9. Sobre Juan Bautista Maíno

    OpenAIRE

    Pérez Sánchez, Alfonso E.

    1997-01-01

    This article published new documents about the activity of the Domenican painter Juan Bautista Maíno specially concerning his concept of the practice of Painting in relation to the other arts. Works hitherto unknown are published here for the first time. Also illustrated are portraits of the Conde de Añover de Tajo and his wife, whose collections were, in addition given valuation by the artista.No disponible

  10. Vaccines against stimulants: cocaine and MA

    Science.gov (United States)

    Kosten, Thomas; Domingo, Coreen; Orson, Frank; Kinsey, Berma

    2014-01-01

    While the worldwide prevalence of cocaine use remains significant, medications, or small molecule approaches, to treat drug addictions have met with limited success. Anti-addiction vaccines, on the other hand, have demonstrated great potential for treating drug abuse using a distinctly different mechanism of eliciting an antibody response that blocks the pharmacological effects of drugs. We provide a review of vaccine-based approaches to treating stimulant addictions; specifically and cocaine addictions. This selective review article focuses on the one cocaine vaccine that has been into clinical trials and presents new data related to pre-clinical development of a methamphetamine (MA) vaccine. We also review the mechanism of action for vaccine induced antibodies to abused drugs, which involves kinetic slowing of brain entry as well as simple blocking properties. We present pre-clinical innovations for MA vaccines including hapten design, linkage to carrier proteins and new adjuvants beyond alum. We provide some new information on hapten structures and linkers and variations in protein carriers. We consider a carrier, outer membrance polysaccharide coat protein (OMPC), that provides some self-adjuvant through lipopolysaccharide components and provide new results with a monophosopholipid adjuvant for the more standard carrier proteins with cocaine and MA. The review then covers the clinical trials with the cocaine vaccine TA-CD. The clinical prospects for advances in this field over the next few years include a multi-site cocaine vaccine clinical trial to be reported in 2013 and phase 1 clinical trials of a MA vaccine in 2014. PMID:23509915

  11. Microcap M&A: An Exploratory Study

    Directory of Open Access Journals (Sweden)

    Keith Turpie

    2014-06-01

    Full Text Available A substantial body of accounting and finance literature has been devoted to the study of Mergers and Acquisitions (M&As dominated by discussions relating to the gains and losses that accrue from transactions involving large public companies. This paper makes a unique contribution to the literature by investigating the M&A experience of microcap businesses. Transactions involving microcap M&A are substantially different to those involving large companies on a number of dimensions. This paper explores the determinants of microcap M&A success and pitfalls and problems from an integration perspective. Due to the paucity of research in the area an exploratory research design is employed, conducting interviews with five CEOs of companies that had each managed multiple transactions. We find microcap M&As are successful when measured against identified goals but generally take longer and cost more than expected. Further, culture and communication are key issues in determining success/failure. We also find the in-house management of integration aspects is problematic for these businesses and suggest this warrants further study.

  12. Exploring MaNGA's kinematic maps

    Science.gov (United States)

    Weijmans, Anne-Marie; MaNGA Team

    2016-01-01

    Different galaxy formation processes leave different imprints on the gas and stellar kinematic patterns for a galaxy. With MaNGA, we now have after one year of observations an unprecedented sample of 1400 nearby galaxies for which we can study gas and stellar kinematics in much detail, based on integral-field spectroscopy. We are measuring kinematic quantities such as LambdaR (angular momentum) and their (possible) correlations with other galaxy properties such as mass, morphology and environment. By quantifying the kinematic (sub)structures in velocity and dispersion maps, we will construct a kinematic galaxy classification that can be linked to their formation processes.

  13. 76 FR 58105 - Regulated Navigation Area; Saugus River, Lynn, MA

    Science.gov (United States)

    2011-09-20

    ... SECURITY Coast Guard 33 CFR Part 165 RIN 1625-AA11 Regulated Navigation Area; Saugus River, Lynn, MA AGENCY... River in Lynn, MA. Establishing this temporary rule will allow the necessary stabilization work to be... on the Energy Systems Pipeline Bridge on the Saugus River in Lynn, MA. The regulated area...

  14. Ma Ying-jeou’s Presidential Discourse

    Directory of Open Access Journals (Sweden)

    Jonathan Sullivan

    2012-01-01

    Full Text Available Despite the substantial advances made in cross-Strait relations during Ma Ying-jeou’s (Ma Yingjiu first term, the ROC president’s rhetoric varied considerably as he grappled with the difficult reality of implementing campaign and inauguration pledges to establish better relations with China while striving to maintain national respect and sovereignty. In this article, we put forward a framework for measuring, analysing and explaining this variation in President Ma’s first-term discourse. Analysing a very large number of Ma’s speeches, addresses, etc., we provide empirical assessments of how the content of Ma’s public pronouncements has developed over time, how his rhetoric varies according to the strategic context and timing of a speech, and how his discourse compares to that of his predecessor, Chen Shui-bian (Chen Shuibian. In addressing these questions, the article contributes a quantitative perspective to existing work on political discourse in Taiwan and to the growing methodological and applied literature on how to systematically analyse Chinese political text.

  15. MaNGA: Target selection and Optimization

    Science.gov (United States)

    Wake, David

    2016-01-01

    The 6-year SDSS-IV MaNGA survey will measure spatially resolved spectroscopy for 10,000 nearby galaxies using the Sloan 2.5m telescope and the BOSS spectrographs with a new fiber arrangement consisting of 17 individually deployable IFUs. We present the simultaneous design of the target selection and IFU size distribution to optimally meet our targeting requirements. The requirements for the main samples were to use simple cuts in redshift and magnitude to produce an approximately flat number density of targets as a function of stellar mass, ranging from 1x109 to 1x1011 M⊙, and radial coverage to either 1.5 (Primary sample) or 2.5 (Secondary sample) effective radii, while maximizing S/N and spatial resolution. In addition we constructed a "Color-Enhanced" sample where we required 25% of the targets to have an approximately flat number density in the color and mass plane. We show how these requirements are met using simple absolute magnitude (and color) dependent redshift cuts applied to an extended version of the NASA Sloan Atlas (NSA), how this determines the distribution of IFU sizes and the resulting properties of the MaNGA sample.

  16. Roadmap to MaRIE March 2015

    Energy Technology Data Exchange (ETDEWEB)

    Barnes, Cris William [Los Alamos National Lab. (LANL), Los Alamos, NM (United States)

    2015-03-30

    Los Alamos National Laboratory’s proposed MaRIE facility is slated to introduce the world’s highest energy hard x-ray free electron laser (XFEL). As the light source for the Matter-Radiation Interactions in Extremes experimental facility (MaRIE), the 42-keV XFEL, with bursts of x-ray pulses at gigahertz repetition for studying fast dynamical processes, will help accelerate discovery and design of the advanced materials needed to meet 21st-century national security and energy security challenges. Yet the science of free-electron lasers has a long and distinguished history at Los Alamos National Laboratory (LANL), where for nearly four decades Los Alamos scientists have been performing research, design, development, and collaboration work in FEL science. The work at Los Alamos has evolved from low-gain amplifier and oscillator FEL development to highbrightness photoinjector development, and later, self-amplified spontaneous emission (SASE) and high-gain amplifier FEL development.

  17. Identification and characterization of novel NuMA isoforms

    Energy Technology Data Exchange (ETDEWEB)

    Wu, Jin, E-mail: petersdu2112@hotmail.com [Key Laboratory for Cell Proliferation and Regulation of the Ministry of Education, Beijing Normal University, Beijing (China); Xu, Zhe [Department of Clinical Laboratory Diagnosis, Beijing Tiantan Hospital, Capital Medical University, Beijing (China); Core Laboratory for Clinical Medical Research, Beijing Tiantan Hospital, Capital Medical University, Beijing (China); He, Dacheng [Key Laboratory for Cell Proliferation and Regulation of the Ministry of Education, Beijing Normal University, Beijing (China); Lu, Guanting, E-mail: guantlv@126.com [Beijing DnaLead Science and Technology Co., LTD, Beijing (China)

    2014-11-21

    Highlights: • Seven NuMA isoforms generated by alternative splicing were categorized into 3 groups: long, middle and short. • Both exons 15 and 16 in long NuMA were “hotspot” for alternative splicing. • Lower expression of short NuMA was observed in cancer cells compared with nonneoplastic controls. • Distinct localization pattern of short isoforms indicated different function from that of long and middle NuMA. - Abstract: The large nuclear mitotic apparatus (NuMA) has been investigated for over 30 years with functions related to the formation and maintenance of mitotic spindle poles during mitosis. However, the existence and functions of NuMA isoforms generated by alternative splicing remains unclear. In the present work, we show that at least seven NuMA isoforms (categorized into long, middle and short groups) generated by alternative splicing from a common NuMA mRNA precursor were discovered in HeLa cells and these isoforms differ mainly at the carboxyl terminus and the coiled-coil domains. Two “hotspot” exons with molecular mass of 3366-nt and 42-nt tend to be spliced during alternative splicing in long and middle groups. Furthermore, full-length coding sequences of long and middle NuMA obtained by using fusion PCR were constructed into GFP-tagged vector to illustrate their cellular localization. Long NuMA mainly localized in the nucleus with absence from nucleoli during interphase and translocated to the spindle poles in mitosis. Middle NuMA displayed the similar cell cycle-dependent distribution pattern as long NuMA. However, expression of NuMA short isoforms revealed a distinct subcellular localization. Short NuMA were present in the cytosol during the whole cycle, without colocalization with mitotic apparatus. These results have allowed us tentatively to explore a new research direction for NuMA’s various functions.

  18. Gondwanaland from 650-500 Ma assembly through 320 Ma merger in Pangea to 185-100 Ma breakup: supercontinental tectonics via stratigraphy and radiometric dating

    Science.gov (United States)

    Veevers, J. J.

    2004-12-01

    Gondwanaland lasted from the 650-500 Ma (late Neoproterozoic-Cambrian) amalgamation of African and South American terranes to Antarctica-Australia-India through 320 Ma (mid-Carboniferous) merging with Laurussia in Pangea to breakup from 185 to 100 Ma (Jurassic and Early Cretaceous). Gondwanaland straddled the equator at 540 Ma, lay wholly in the Southern Hemisphere by 350 Ma, and then rotated clockwise so that at 250 Ma Australia reached the S pole and Africa the equator. By initial breakup of Pangea at 185 Ma, Gondwanaland had moved northward such that North Africa reached 35°N. The first clear picture of Gondwanaland, in the Cambrian, shows the assembly of continents with later Laurentian, European and Asian terranes along the "northern" margin, and with a trench along the "western" and "southern" margins, reflected by a 10,000-km-long chain of 530-500 Ma granites. The interior was crossed by the Prydz-Leeuwin and Mozambique Orogenic Belts. The shoreline lapped the flanks of uplifts generated during this complex terminal Pan-Gondwanaland (650-500 Ma) deformation, which endowed Gondwanaland with a thick, buoyant crust and lithosphere and a nonmarine siliciclastic facies. During the Ordovician, terranes drifted from Africa as the first of many transfers of material to the "northern" continents. Central Australia was crossed by the sea, and the eastern margin and ocean floor were flooded by grains of quartz (and 600-500 Ma zircon) from Antarctica. Ice centres in North Africa and southern South America/Africa waxed and waned in the latest Ordovician, Early Silurian, latest Devonian, and Early Carboniferous. In the mid-Carboniferous, Laurussia and Gondwanaland merged in the composite called Pangea by definitive right-lateral contact along the Variscan suture, with collisional stress and subsequent uplift felt as far afield as Australia. Ice sheets developed on the tectonic uplands of Gondwanaland south of 30°S. In the Early Permian, the self-induced heat beneath

  19. 论维吾尔语否定成分-ma-/-ma-的句法特性

    Institute of Scientific and Technical Information of China (English)

    力提甫·托乎提

    2011-01-01

    本文在乔姆斯基最简方案理论的启发下,首先肯定维吾尔语否定成分-ma-/-ma-可以构成否定短语(NEGP=negation phrase)。在此基础上,探讨-ma-/-ma-的否定范围,包括无标记否定结构、用音强缩小或转移否定范围、否定焦点的选定、否定意义的强化、否定结构的歧义以及句子的否定、复杂结构中的否定和双否定等问题,揭示-ma-/-ma-的句法特性。%The Chomskyan theory of generative syntax, especially the Minimalist Program, enables us to rethink on Uyghur inflectional suffixes. Guided by this theory, this paper first confirms that the Uyghur negative suffix -ma-/-ma-can form its own NEGP (negation phrase). Then it explores the scope of negation, including the unmarked negation structure, reduced or transferred negation, focus of negation, intensified negation, ambiguity of negation, sentential negation, and complex and double negation, attempting to explain the syntactic property of the negative suffix-ma-/-ma-.

  20. Changing the S and MA [Safety and Mission Assurance] Paradigm

    Science.gov (United States)

    Malone, Roy W., Jr.

    2010-01-01

    Objectives: 1) Optimize S&MA organization to best facilitate Shuttle transition in 2010, successfully support Ares developmental responsibilities, and minimize the impacts of the gap between last Shuttle flight and start of Ares V Project. 2) Improve leveraging of critical skills and experience between Shuttle and Ares. 3) Split technical and supervisory functions to facilitate technical penetration. 4) Create Chief Safety and Mission Assurance Officer (CSO) stand-alone position for successfully implementation of S&MA Technical Authority. 5) Minimize disruption to customers. 6) Provide early involvement of S&MA leadership team and frequent/open communications with S&MA team members and steak-holders.

  1. E-Government in Lithuania – Local Self-Government Layer Elektroninė valdžia Lietuvoje: savivaldos pjūvis

    Directory of Open Access Journals (Sweden)

    Elena Raginytė

    2011-02-01

    . Tačiau vis dar susiduria su techninėmis, teisinėmis ir metodologinėmis problemomis, kurios nesudaro prielaidų užtikrinti e. valdžios veiksmingumui. E. valdžios plėtros būtinybę bei aktualumą rodo ir tai, jog šalys, neplėtojančios e. valdžios, investuotojų vertinamos vis nepalankiau, nes tokio pobūdžio paslaugos kitose šalyse yra nuolat ir aktyviai plėtojamos. Esminis Lietuvos ekonominės politikos uždavinys šiandien yra padidinti palies konkurencingumą. Kaip rodo įvairūs nacionaliniai ir tarptautiniai tyrimai, žemas viešojo administravimo veiksmingumo lygis (įskaitant korupciją yra stiprus veiksnys, mažinantis įmonių konkurencingumą ir šalies patrauklumą joje investuoti bei gyventi. Reikia pažymėti, kad iki šio laikotarpio atlikta nemažai darbų ir įgyvendinta e. valdžios koncepcijos projektų. Tačiau pastebima dar gana daug e. valdžios plėtros planuose numatytų, bet neįgyvendintų uždavinių, neišspręstų problemų. Tyrimo tikslas – ištirti ir įvertinti savivaldos lygmeniu teikiamų elektroninių paslaugų kokybę. Siekiant įgyvendinti šį tikslą buvo iškelti tokie tyrimo uždaviniai: išanalizuoti elektroninės valdžios plėtros problemas, atlikti Lietuvos savivaldybių internetinių svetainių vertinimus, ištirti savivaldybių darbuotojų kompiuterinio raštingumo lygį ir remiantis tyrimų rezultatais išnagrinėti priežastis, ribojančias naudojimosi elektroninėmis paslaugomis galimybes.

    Raktiniai žodžiai: 42 CFR 422.50 - Eligibility to elect an MA plan.

    Science.gov (United States)

    2010-10-01

    ... 42 Public Health 3 2010-10-01 2010-10-01 false Eligibility to elect an MA plan. 422.50 Section 422... Eligibility to elect an MA plan. For this subpart, all references to an MA plan include MA-PD and both MA local and MA regional plans, as defined in § 422.2 unless specifically noted otherwise. (a)...

  2. 42 CFR 422.103 - Benefits under an MA MSA plan.

    Science.gov (United States)

    2010-10-01

    ... 42 Public Health 3 2010-10-01 2010-10-01 false Benefits under an MA MSA plan. 422.103 Section 422... Benefits under an MA MSA plan. (a) General rule. An MA organization offering an MA MSA plan must make...) Countable expenses. An MA organization offering an MA MSA plan must count toward the annual deductible...

  3. MaROS: Information Management Service

    Science.gov (United States)

    Allard, Daniel A.; Gladden, Roy E.; Wright, Jesse J.; Hy, Franklin H.; Rabideau, Gregg R.; Wallick, Michael N.

    2011-01-01

    This software is provided by the Mars Relay Operations Service (MaROS) task to a variety of Mars projects for the purpose of coordinating communications sessions between landed spacecraft assets and orbiting spacecraft assets at Mars. The Information Management Service centralizes a set of functions previously distributed across multiple spacecraft operations teams, and as such, greatly improves visibility into the end-to-end strategic coordination process. Most of the process revolves around the scheduling of communications sessions between the spacecraft during periods of time when a landed asset on Mars is geometrically visible by an orbiting spacecraft. These relay sessions are used to transfer data both to and from the landed asset via the orbiting asset on behalf of Earth-based spacecraft operators. This software component is an application process running as a Java virtual machine. The component provides all service interfaces via a Representational State Transfer (REST) protocol over https to external clients. There are two general interaction modes with the service: upload and download of data. For data upload, the service must execute logic specific to the upload data type and trigger any applicable calculations including pass delivery latencies and overflight conflicts. For data download, the software must retrieve and correlate requested information and deliver to the requesting client. The provision of this service enables several key advancements over legacy processes and systems. For one, this service represents the first time that end-to-end relay information is correlated into a single shared repository. The software also provides the first multimission latency calculator; previous latency calculations had been performed on a mission-by-mission basis.

  4. 人物专栏:马军%Personage Column: MA Jun

    Institute of Scientific and Technical Information of China (English)

    2006-01-01

    @@ Ma Jun is the Head of Harbin Institute of Hematology & Oncology that serves as a teaching, research and medical center of hematology and oncology in China. Dr. Ma is a very famous professor of Hematology and Oncology in the county and abroad now.

  5. Van maïsstengel tot ethanol, eiwitten en energie

    NARCIS (Netherlands)

    Laar, E.; Sanders, J.P.M.

    2010-01-01

    Maïs wordt in een bioethanolinstallatie in Lelystad verwerkt voor de productie van ethanol, eiwitten en energie. ZeaFuels heeft een methode ontwikkeld waarmee direct bij de boerderij via de vergisting van maïs het maximale uit de grondstof kan worden gehaald

  6. 77 FR 1503 - Massasoit National Wildlife Refuge, Plymouth, MA

    Science.gov (United States)

    2012-01-10

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF THE INTERIOR Fish and Wildlife Service Massasoit National Wildlife Refuge, Plymouth, MA AGENCY: Fish and Wildlife... Hill Road, Sudbury, MA 01776. In-Person Drop-off: You may drop off comments during regular...

  7. "Sel kevadel olen ma eriti ilus..." : [luuletused] / Triin Soomets

    Index Scriptorium Estoniae

    Soomets, Triin

    2003-01-01

    Sisu: "Sel kevadel olen ma eriti ilus..." ; "Tahaksin teha midagi tõelist; midagi suurt..." ; "veebruaris on keha nii valge et syda läheb pahaks..." ; "kõige kohutavamad lepingud..." ; "Igal loojangul kutsun sind ja igal koidikul tõukan su ära..." ; "need hakid..." ; "Põhja vajudes on viimane asi, mida ma näen, rohelised sähvatused..."

  8. Lernen durch aktive Partizipation in der klinischen Patientenversorgung - Machbarkeitsstudie einer internistischen PJ-Ausbildungsstation [Learning by active participation in clinical care - a feasibility study of a clinical education ward in internal medicine

    Directory of Open Access Journals (Sweden)

    Tauschel, Diethard

    2009-08-01

    competency fields, with the highest progress having been made in organization and ward management. Conclusions: The main stakeholders (patients, staff members, students see significant advantages in the specific combination of patient care and clinical education at the CEW. Further studies have to be performed to analyze the long-term effects of the CEW as well as its function as a model for other teaching hospitals. [german] Hintergrund und Ziele: Für das Tertial Innere Medizin schreibt die in Deutschland geltende Ärztliche Approbationsordnung eine stationsgebundene Ausbildung von 16 Wochen vor. Die Ausbildung im Praktischen Jahr (PJ sollte im Kontext des späteren beruflichen Umfeldes und kompetenzbasiert erfolgen. Die wesentlichen Ziele des hier beschriebenen Projektes liegen darin, erstens eine Ausbildungsstation für eine praxisnahe und selbstgesteuerte Ausbildung von PJ-Studierenden aufzubauen sowie zweitens unter Beteiligung der relevanten Personengruppen (Patienten, Mitarbeiter, Studierende die Auswirkungen dieses Modells auf Patientenversorgung, Stationsorganisation und Lernprozess der Studierenden zu untersuchen. Dabei sollen die Voraussetzungen für eine „lernende Organisation“ geschaffen werden. Methoden: Im Herbst 2007 wurde im Rahmen eines Pilotprojektes eine Ausbildungsstation in einer internistischen Abteilung aufgebaut. Dabei übernehmen Studierende im PJ als „Ärzte unter Supervision“ die Betreuung der Patienten. Sie werden dabei fachärztlich angeleitet und supervidiert. Alle behandelten Patienten wurden nach Entlassung mittels eines Fragebogens zu einer Beurteilung der studentischen Integration in die Patientenversorgung aufgefordert. Ebenso wurden alle beteiligten Mitarbeiter (Ärzte, Pflegende, Therapeuten bezüglich der Veränderungen in der Stationsorganisation und der interprofessionellen Zusammenarbeit befragt. Mit den Studierenden wurden vor dem Tertial Ausbildungsziele in definierten Kompetenzfeldern vereinbart. Die Studierenden sch

  9. El álbum visual como nueva forma promocional de la industria de la música: el caso de Let England Shake de PJ Harvey y Seamus Murphy

    Directory of Open Access Journals (Sweden)

    Ana María Sedeño-Valdellós

    2016-01-01

    Full Text Available El nuevo modelo de negocio para la industria fonográfica comienza a basar se en los contenidos digitales. Varios autores han estudiado y afirman que la industria musical experimenta un giro hacia el contenido audiovisual. Esto se enmarca en una nueva etapa de estética audiovisual caracterizada por la transmedialidad y la convergencia de medios en torno a formatos audiovi suales complejos. El álbum visual, como concepto formado por videoclips de todas las canciones de un disco, se consolida como un nuevo formato de promocional musical, híbrido entre cine y video musical. En el traba jo se realizará un análisis del álbum visual Let England Shake (PJ Harvey & Seamus Murphy, 2011, con unos criterios que tratan de buscar moti vos visuales que generen continuidad, unidad temática y narrativa para de mostrar su intensa coherencia con el álbum musical precedente. Se trata de definir el álbum visual y comenzar a delimitarlo frente a otros tipos de productos audiovisuales, así como examinar sus posibilidades de creación de sentido en la generación de una narrativa personal diferenciada para un artista/grupo musical.

  10. Morotochoerus from Uganda (17.5 Ma and Kenyapotamus from Kenya (13-11 Ma: implications for hippopotamid origins

    Directory of Open Access Journals (Sweden)

    Pickford, M.

    2011-12-01

    Full Text Available The aim of this paper is to describe and interpret suiform teeth from Moroto, Uganda, and Ngorora, Kenya, which contribute to the debate about hippo-anthracothere-whale relationships. The early stages of hippopotamid evolution are relatively poorly known on account of the paucity of their fossil record older than 7 Ma. New specimens of Morotochoerus from Uganda reveal that it is not closely related to Hippopotamidae; the superficial resemblances of the cheek teeth to those of hippos represent convergences and not homologies. Restricted samples of Palaeopotamus ternani are available from the Middle Miocene of Kenya {Maboko, ca 16 Ma; Muruyur, ca 14.5 Ma; Fort Ternan, ca 13.7 Ma} while from the base of the late Miocene, Kenyapotamus coryndonae is known from Kenya {Ngerngerwa, ca 10.5-10 Ma; Nakali, ca 10.5 Ma; Samburu Hills, ca 9.5 Ma}, Ethiopia {Ch’orora, ca 10.5 Ma} and Tunisia {Beglia Formation ca 11-10 Ma}. The recovery of specimens of Kenyapotamus from the Ngorora Formation, Kenya, aged ca 11 Ma, is of interest because it includes well preserved teeth, including an m/3 in good condition. These specimens support the hypothesis that hippopotamids descended from palaeochoerids and not from anthracotheres.El objetivo de este trabajo es describir e interpretar los dientes suiformes de Moroto, Uganda, y Ngorora, Kenia, que contribuyen al debate sobre las relaciones hipo-anthracothere-whale. Las primeras etapas de la evolución de los hipopotámidos son relativamente poco conocidas a causa de la escasez de su registro fósil en edades superiors a los 7 Ma. Nuevos ejemplares de Morotochoerus en Uganda revelan que no están estrechamente relacionados con Hippopotamidae, las semejanzas superficiales de los dientes de la mandíbula con los de los hipopótamos representan convergencias y no homologías. Algunas muestras de Palaeopotamus ternani aparecen en el Medio Mioceno de Kenia {Maboko, ca 16 Ma; Muruyur, ca 14.5 Ma; Fort Ternan, ca 13.7 Ma

  11. Characterization and expression profiles of MaACS and MaACO genes from mulberry (Morus alba L.)%桑树MaACS和MaACO基因的鉴定和表达模式研究

    Institute of Scientific and Technical Information of China (English)

    Chang-ying LIU; Shu-mei HAN; Cheng LU; Mao-de YU; Rui-hua LÜ; Jun LI; Ai-chun ZHAO; Xi-ling WANG; Umuhoza DIANE; Xiao-hong WANG; Chuan-hong WANG; Ya-sheng YU

    2014-01-01

    研究目的:分离和鉴定桑树中参与乙烯生物合成的酶的编码基因MaACS 和MaACO,研究其表达模式。创新要点:基于最新公布的桑树基因组数据库数据,获得5个MaACS 基因和2个MaACO 基因,对其进行了生物信息分析,同时鉴定了其在不同桑树组织中、不同发育时期桑椹中和不同激素作用下的表达模式。研究方法:通过生物信息学方法筛选和鉴定基因,利用荧光定量逆转录聚合酶链式反应(qRT-PCR)分析基因的表达量。重要结论:MaACS 和MaACO 基因在根、茎、叶等不同组织中呈现出不同的表达模式,在桑椹发育过程中呈现出两种表达模式,其表达量被脱落酸和乙烯利上调。%1-Aminocyclopropane-1-carboxylic acid synthase (ACS) and 1-aminocyclopropane-1-carboxylic acid oxidase (ACO) are encoded by multigene families and are involved in fruit ripening by catalyzing the production of ethylene throughout the development of fruit. However, there are no reports on ACS or ACO genes in mulberry, partly because of the limited molecular research background. In this study, we have obtained five ACS gene sequences and two ACO gene sequences from Morus Genome Database. Sequence alignment and phylogenetic analysis of MaACO1 and MaACO2 showed that their amino acids are conserved compared with ACO proteins from other species. MaACS1 and MaACS2 are type I, MaACS3 and MaACS4 are type II, and MaACS5 is type III, with different C-terminal se-quences. Quantitative reverse transcriptase polymerase chain reaction (qRT-PCR) expression analysis showed that the transcripts of MaACS genes were strongly expressed in fruit, and more weakly in other tissues. The expression of MaACO1 and MaACO2 showed different patterns in various mulberry tissues. MaACS and MaACO genes demon-strated two patterns throughout the development of mulberry fruit, and both of them were strongly up-regulated by abscisic acid (ABA) and ethephon.

  12. Crossed-beam reaction of carbon atoms with hydrocarbon molecules. V. Chemical dynamics of n-C4H3 formation from reaction of C(3Pj) with allene, H2CCCH2(X 1A1)

    Science.gov (United States)

    Kaiser, R. I.; Mebel, A. M.; Chang, A. H. H.; Lin, S. H.; Lee, Y. T.

    1999-06-01

    The crossed molecular beams technique was employed to investigate the reaction between ground state carbon atoms, C(3Pj), and allene, H2CCCH2(X 1A1), at two averaged collision energies of 19.6 and 38.8 kJ mol-1. Product angular distributions and time-of-flight spectra of C4H3 were recorded. Forward-convolution fitting of the data yields weakly polarized center-of-mass angular flux distributions isotropic at lower, but forward scattered with respect to the carbon beam at a higher collision energy. The maximum translational energy release and the angular distributions combined with ab initio and RRKM calculations are consistent with the formation of the n-C4H3 radical in its electronic ground state. The channel to the i-C4H3 isomer contributes less than 1.5%. Reaction dynamics inferred from the experimental data indicate that the carbon atom attacks the π-orbitals of the allenic carbon-carbon double bond barrierless via a loose, reactant-like transition state located at the centrifugal barrier. The initially formed cyclopropylidene derivative rotates in a plane almost perpendicular to the total angular momentum vector around its C-axis and undergoes ring opening to triplet butatriene. At higher collision energy, the butatriene complex decomposes within 0.6 ps via hydrogen emission to form the n-C4H3 isomer and atomic hydrogen through an exit transition state located 9.2 kJ mol-1 above the products. The explicit identification of the n-C4H3 radical under single collision represents a further example of a carbon-hydrogen exchange in reactions of ground state carbon atoms with unsaturated hydrocarbons. This channel opens a barrierless route to synthesize extremely reactive hydrocarbon radicals in combustion processes, interstellar chemistry, and hydrocarbon-rich atmospheres of Jupiter, Saturn, Titan, as well as Triton.

  13. Contact Aligner 2 (Front Side): Suss Microtec MA8

    Data.gov (United States)

    Federal Laboratory Consortium — Description:CORAL Name: SussMA8This system utilizes 1X contact lithography to transfer photomask patterns onto substrates Specifications / Capabilities:UV broadband...

  14. 76 FR 19911 - Drawbridge Operation Regulations; Apponagansett River, Dartmouth, MA

    Science.gov (United States)

    2011-04-11

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF HOMELAND SECURITY Coast Guard 33 CFR Part 117 Drawbridge Operation Regulations; Apponagansett River, Dartmouth, MA AGENCY: Coast Guard, DHS. ACTION: Notice of temporary deviation from regulations. SUMMARY: The...

  15. 76 FR 37041 - Drawbridge Operation Regulation; Apponagansett River, Dartmouth, MA

    Science.gov (United States)

    2011-06-24

    ..., issue of the Federal Register (73 FR 3316). Public Meeting We do not now plan to hold a public meeting..., Dartmouth, MA AGENCY: Coast Guard, DHS. ACTION: Notice of proposed rulemaking. SUMMARY: The Coast...

  16. 77 FR 25890 - Drawbridge Operation Regulations; Manchester Harbor, Manchester, MA

    Science.gov (United States)

    2012-05-02

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF HOMELAND SECURITY Coast Guard 33 CFR Part 117 Drawbridge Operation Regulations; Manchester Harbor, Manchester, MA AGENCY: Coast Guard, DHS. ACTION: Notice of temporary deviation from regulations. SUMMARY: The...

  17. Zhi Liao:Ma Liang Solo Visual Exhibition

    Institute of Scientific and Technical Information of China (English)

    Jade; Franklin

    2007-01-01

    can prove to be simultaneously amusing and macabre, as if to him there is no distinction between the two. Prior to focusing on photography Ma Liang worked as a short-film director and cinematographer. The evidence of this is

  18. MaNGA: Mapping Nearby Galaxies at Apache Point Observatory

    CERN Document Server

    Weijmans, Anne-Marie

    2015-01-01

    MaNGA (Mapping Nearby Galaxies at APO) is a galaxy integral-field spectroscopic survey within the fourth generation Sloan Digital Sky Survey (SDSS-IV). It will be mapping the composition and kinematics of gas and stars in 10,000 nearby galaxies, using 17 differently sized fiber bundles. MaNGA's goal is to provide new insights in galaxy formation and evolution, and to deliver a local benchmark for current and future high-redshift studies.

  19. 46 CFR 7.15 - Massachusetts Bay, MA.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 1 2010-10-01 2010-10-01 false Massachusetts Bay, MA. 7.15 Section 7.15 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY PROCEDURES APPLICABLE TO THE PUBLIC BOUNDARY LINES Atlantic Coast § 7.15 Massachusetts Bay, MA. A line drawn from latitude 42°37.9′ N. longitude 70°31.2′ W. (Cape...

  1. A new 40 MA ranchero explosive pulsed power system

    Energy Technology Data Exchange (ETDEWEB)

    Goforth, James [Los Alamos National Laboratory; Herrera, Dennis [Los Alamos National Laboratory; Oona, Hank [Los Alamos National Laboratory; Torres, David [Los Alamos National Laboratory; Atchison, W L [Los Alamos National Laboratory; Colgate, S A [Los Alamos National Laboratory; Griego, J R [Los Alamos National Laboratory; Guzik, J [Los Alamos National Laboratory; Holtkamp, D B [Los Alamos National Laboratory; Idzorek, G [Los Alamos National Laboratory; Kaul, A [Los Alamos National Laboratory; Kirkpatrick, R C [Los Alamos National Laboratory; Menikoff, R [Los Alamos National Laboratory; Reardon, P T [Los Alamos National Laboratory; Reinovsky, R E [Los Alamos National Laboratory; Rousculp, C L [Los Alamos National Laboratory; Sgro, A G [Los Alamos National Laboratory; Tabaka, L J [Los Alamos National Laboratory; Tierney, T E [Los Alamos National Laboratory; Watt, R G [Los Alamos National Laboratory

    2009-01-01

    We are developing a new high explosive pulsed power (HEPP) system based on the 1.4 m long Ranchero generator which was developed in 1999 for driving solid density z-pinch loads. The new application requires approximately 40 MA to implode similar liners, but the liners cannot tolerate the 65 {micro}s, 3 MA current pulse associated with delivering the initial magnetic flux to the 200 nH generator. To circumvent this problem, we have designed a system with an internal start switch and four explosively formed fuse (EFF) opening switches. The integral start switch is installed between the output glide plane and the armature. It functions in the same manner as a standard input crowbar switch when armature motion begins, but initially isolates the load. The circuit is completed during the flux loading phase using post hole convolutes. Each convolute attaches the inner (coaxial) output transmission line to the outside of the outer coax through a penetration of the outer coaxial line. The attachment is made with the conductor of an EFF at each location. The EFFs conduct 0.75 MA each, and are actuated just after the internal start switch connects to the load. EFFs operating at these parameters have been tested in the past. The post hole convolutes must withstand as much as 80 kV at peak dl/dt during the Ranchero load current pulse. We describe the design of this new HEPP system in detail, and give the experimental results available at conference time. In addition, we discuss the work we are doing to test the upper current limits of a single standard size Ranchero module. Calculations have suggested that the generator could function at up to {approx}120 MA, the rule of thumb we follow (1 MA/cm) suggests 90 MA, and simple flux compression calculations, along with the {approx}4 MA seed current available from our capacitor bank, suggests 118 MA is the currently available upper limit.

  2. MaNGA: Mapping Nearby Galaxies at Apache Point Observatory

    Science.gov (United States)

    Weijmans, A.-M.; MaNGA Team

    2016-10-01

    MaNGA (Mapping Nearby Galaxies at APO) is a galaxy integral-field spectroscopic survey within the fourth generation Sloan Digital Sky Survey (SDSS-IV). It will be mapping the composition and kinematics of gas and stars in 10,000 nearby galaxies, using 17 differently sized fiber bundles. MaNGA's goal is to provide new insights in galaxy formation and evolution, and to deliver a local benchmark for current and future high-redshift studies.

  3. SDSS-IV MaNGA: Project Overview

    Science.gov (United States)

    Bundy, Kevin; MaNGA Team

    2016-01-01

    I present an overview of the scientific motivation and basic design of the Sloan Digital Sky Survey-IV program, MaNGA: Mapping Nearby Galaxies at Apache Point Observatory. MaNGA is currently in its second year of operations with roughly 2000 galaxies now observed, already the largest integral field spectroscopic survey of galaxies ever conducted. By combining the wealth of information made available by resolved spectroscopy with the statistical power of a sample of 10,000 galaxies, MaNGA is providing transformative insights on key questions about the life history of galaxies. These questions range from the nature of growth of star-forming disks and stellar spheroidals, to the physical origin of star formation quenching, to the ways in which the different mass components in galaxies interact and assemble over time. MaNGA's success owes to a dedicated team of scientists, engineers, and observers working to optimize the survey operations and develop advanced data processing, analysis, and interface tools in order to fully realize MaNGA's exciting potential. Continuing in the Sloan tradition, MaNGA data products will be made publicly available, with the first release scheduled for Summer 2016.

  4. Seasonal and daily patterns of group size, cohesion and activity of the estuarine dolphin, Sotalia guianensis (P.J. van Bénéden (Cetacea, Delphinidae, in southern Brazil Padrões sazonais e diários do tamanho de grupo, coesão e atividade do boto-cinza, Sotalia guianensis (P.J. van Bénéden (Cetacea, Delphinidae, no sul do Brasil

    Directory of Open Access Journals (Sweden)

    Fábio G. Daura-Jorge

    2005-12-01

    Full Text Available The resident population of estuarine dolphin, Sotalia guianensis (P.J. van Bénéden, 1864, in Norte Bay, Santa Catarina, southern Brazil, was studied from 2000 to 2003. Systematic one-day cruises were undertaken aboard a 5 m sail boat equipped with an outboard motor. Applying the focal-group method, information such as geographical position, predominant behavioural patterns, group size, cohesion index and the presence of calves, were registered at every five-minute interval, totalling 198 hours of direct observation of the dolphins. The estuarine dolphin used preferential areas for each behavioural pattern. The mean group size was approximately 29 individuals, and the presence of calves occurred throughout the entire year, but with a significant increase in the warm seasons. The frequency of behavioural patterns and group size varied according to season and time of day, and were strongly associated. The frequency of moving behaviours increased in the cold seasons and along the day. The seasonal variation in the moving behaviours suggest the requirement of a larger area in the cold seasons, probably related to seasonal fluctuations in the abundance of dominant prey items. Higher group sizes were observed while dolphins were foraging. The cohesion index also varied according to the behaviour. Our results showed that group organization and behavioural patterns of this estuarine dolphin population are probably linked to daily and seasonal environment cycles, and also possibly to the condition of being at the furthest southern limit of distribution of the species.A população residente de boto-cinza, Sotalia guianensis (P.J. van Bénéden, 1864, da Baía Norte, Santa Catarina, sul do Brasil, foi estudada de 2000 a 2003. Foram realizados cruzeiros sistemáticos de um dia, a bordo de um veleiro de 5 m equipado com motor de popa. Utilizando o método de grupo-focal, informações como posição geográfica, padrão comportamental predominante, tamanho

  5. Increase in physical activities in kindergarten children with cerebral palsy by employing MaKey-MaKey-based task systems.

    Science.gov (United States)

    Lin, Chien-Yu; Chang, Yu-Ming

    2014-09-01

    In this study, we employed Flash- and Scratch-based multimedia by using a MaKey-MaKey-based task system to increase the motivation level of children with cerebral palsy to perform physical activities. MaKey MaKey is a circuit board that converts physical touch to a digital signal, which is interpreted by a computer as a keyboard message. In this study, we used conductive materials to control this interaction. This study followed single-case design using ABAB models in which A indicated the baseline and B indicated the intervention. The experiment period comprised 1 month and a half. The experimental results demonstrated that in the case of two kindergarten children with cerebral palsy, their scores were considerably increased during the intervention phrases. The developmental applications of the results are also discussed.

  6. 75 FR 38128 - Sensata Technologies MA, Inc., Power Controls Division, Formerly Known As Airpax Corp., Cambridge...

    Science.gov (United States)

    2010-07-01

    ... Employment and Training Administration Sensata Technologies MA, Inc., Power Controls Division, Formerly Known..., 2010, applicable to workers of Sansata Technologies MA, Incorporated, Power Controls Division, formerly... under the control of the Cambridge, Maryland location of Sensata Technologies MA, Incorporated,...

  7. Pyroxenite in the Galapagos plume source at 65 Ma

    Science.gov (United States)

    Whalen, W. T.; Gazel, E.; Vidito, C. A.; Herzberg, C. T.; Class, C.; Bizimis, M.; Alvarado-Induni, G.

    2013-12-01

    Mantle plumes originate from boundary layers below the upper mantle. Their surface expressions as hotspot tracks have been linked to voluminous outpourings of lava in the form of large igneous provinces. The Galapagos hotspot has been active since ~90 Ma and the oldest lavas of its associated submarine ridge have been dated to ~14 Ma, subducting at the Middle America Trench, off Costa Rica. The Galapagos plume head magmatic production is preserved as the Caribbean Large Igneous Province (CLIP). A series of 15-65 Ma accreted Galapagos paleo-ridges and islands/seamounts are accreted in the Pacific coast of Costa Rica and Panama. One of these accreted terranes, the Quepos block on the west coast of Costa Rica is an ancient, ~65 Ma Galapagos island. Olivine phenocrysts from Quepos picrites have elevated Ni and low Ca and Mn and Fe/Mn indicative of a dominant pyroxenite source component while CLIP samples are dominated by a peridotite source. The mantle potential temperature (max) of the plume changed from ~1650 to ~1550 C at 65 Ma. This change correlates with the first appearance of the pyroxenite component and an EMII signature (Northern Galapagos Domain) in the Galapagos plume. A relatively dense pyroxenite component may provide a mechanism for the change in Tp due to its effect on the plume's bouyancy. Alternatively, the pyroxenite component was diluted by high peridotite melt fraction during the massive production of the CLIP.

  8. Molecular evolution of the Sorghum Maturity Gene Ma3.

    Science.gov (United States)

    Wang, Yan; Tan, Lubin; Fu, Yongcai; Zhu, Zuofeng; Liu, Fengxia; Sun, Chuanqing; Cai, Hongwei

    2015-01-01

    Time to maturity is a critical trait in sorghum (Sorghum bicolor) breeding, as it determines whether a variety can be grown in a particular cropping system or ecosystem. Understanding the nucleotide variation and the mechanisms of molecular evolution of the maturity genes would be helpful for breeding programs. In this study, we analyzed the nucleotide diversity of Ma3, an important maturity gene in sorghum, using 252 cultivated and wild sorghum materials from all over the world. The nucleotide variation and diversity were analyzed based both on race- and usage-based groups. We also sequenced 12 genes around the Ma3 gene in 185 of these materials to search for a selective sweep and found that purifying selection was the strongest force on Ma3, as low nucleotide diversity and low-frequency amino acid variants were observed. However, a very special mutation, described as ma3R, seemed to be under positive selection, as indicated by dramatically reduced nucleotide variation not only at the loci but also in the surrounding regions among individuals carrying the mutations. In addition, in an association study using the Ma3 nucleotide variations, we detected 3 significant SNPs for the heading date at a high-latitude environment (Beijing) and 17 at a low-latitude environment (Hainan). The results of this study increases our understanding of the evolutionary mechanisms of the maturity genes in sorghum and will be useful in sorghum breeding.

  9. 钟理和:以“左翼”的姿态冲撞民俗的囚笼--兼与蔡登秋先生商榷%Chung Li-ho:Clashing with the Cage of Folk Customs in a‘Leftwing’Posture, and also in Consultation with Mr Cai Dengqiu

    Institute of Scientific and Technical Information of China (English)

    赖一郎

    2015-01-01

    钟理和缺席日据时代台湾皇民化阶段,是一颗遗落的“左翼”种子,崇尚“赛先生”和“德先生”,与主持《联合报》副刊的林海音等人有暗合之处,其塑造的平妹形象为台湾文坛吹进了一股清新的风;《笠山农场》热情地歌颂年轻人对封建习俗的反抗斗争精神。后半生的钟理和却为民俗所包围,陷入了人间炼狱。返台初期的作品依然保持着强烈的社会批判精神,但1954年次子立民夭折对他产生巨大的精神打击。此后的作品依然带有微讽的意味,斗志却逐渐被消磨,民俗书写越来越凸显。%Chung Li-ho, absent from the kōminka period of Taiwan in the Japanese occupation era, was a lost‘leftwing’ seed, who worshipped‘Mr Science’and‘Mr Democracy’and whose ideas happened to accord with those of such people as Lin Haiyin, affiliated with the literary supplement of The United Daily News. The image of Ping Mei(or Younger Sister Ping), one of his fictional protagonists, brought a new breath of breeze into the world of letters in Taiwan, and his Lishan Nongchang (The Farm at Lishan Mountain), passionately sings of the spirit of the young in their fight against the feudalistic customs. In the latter part of his life, however, Chung Li-ho, surrounded by the folk customs, was plunged into a hell on earth. Although his work in the early days of his return to Taiwan retained its spirit of strong social critique, but the death of his second son, Li-min, in 1954, came as a great spiritual blow to him. Even though his subsequent work remained slightly ironic, his fighting spirit had worn down and his writing became sharply oriented towards the folk customs.

  10. L'espace des francs-maçons

    OpenAIRE

    2015-01-01

    À l’heure où l’on commémore avec faste les 275 ans de la franc-maçonnerie en France, ce livre est né d’un constat inquiétant et d’un espoir. Longtemps pionnière dans l’observation des formes de sociabilité, l’histoire de la franc-maçonnerie peine aujourd’hui à trouver un second souffle. Elle est même menacée de marginalisation universitaire et scientifique. Paradoxalement, la situation n’a sans doute jamais été aussi propice à une relance de la recherche : l’ouverture des fonds maçonniques de...

  11. Atmel maXTouch控制器支持Windows 8

    Institute of Scientific and Technical Information of China (English)

    2011-01-01

    爱特梅尔公司(Atmel Corporation)宣布,爱特梅尔maXTouch mXT1386率先成为能够支持微软(Microsoft)公司全新的以触摸为中心的Windows 8操作系统的触摸控制器,此前mXT1386控制器已经用于三星(Samsung)公司的Windows Developer Preview(开发者预览版)PC。mXT1386控制器利用爱特梅尔获得验证的maXTouch技术,是爱特梅尔maXTouch系列中首款支持Windows8操作系统的产品,适用于多种尺寸的触摸屏。

  12. Examples for Clinical Use of Ma Zi Ren Wan

    Institute of Scientific and Technical Information of China (English)

    张书文

    2002-01-01

    @@ Ma Zi Ren Wan (麻子仁丸), originally recorded in Treatise on Febrile Diseases (伤寒论), is composed of Ma Zi Ren (麻子仁Fructus Cannabis), Bai Shao (白芍Radix Paeoniae Alba), Zhi Shi (枳实Fructus Aurantii Immaturus), Da Huang (大黄Radix etRhizoma Rhei), Hou Po (厚朴cortex Magnoliae Officinalis) and Xing Ren (杏仁Semen Armeniacae Amarum). Good therapeutic results have been achieved by using Ma ZiRen Wan in treatment of febrile disease at the restoring stage, chronic consumptive diseases, hemorrhoid, disorders in women after delivery, chronic kidney disease, senile constipation, pulmonary heart disease, diabetes, coronary heart disease and hypertension. Some illustrative cases are introduced below.

  13. Changing the Safety and Mission Assurance (S and MA) Paradigm

    Science.gov (United States)

    Malone, Roy W.; Safie, Fayssal M.

    2010-01-01

    This slide presentation reviews the change in the work and impact of the Safety and Mission Assurance directorate at Marshall Space Flight Center. It reviews the background and the reasons given for a strong Safety & Mission Assurance presence in all planning for space flight. This was pointed out by the Rogers Commission Report after the Space Challenger accident, by the Columbia Accident Investigation Board (CAIB) and by a 2006 NASA Exploration Safety Study (NESS) Team. The overall objective of the work in this area was to improve and maintain S&MA expertise and skills. Training for this work was improved and the S&MA organization was reorganized. This has resulted in a paradigm shift for NASA's safety efforts, which is described. The presentation then reviews the impact of the new S&MA work in the Ares I design and development.

  14. Akuntansi dalam Penetapan Sĩma Masa Jawa Kuno

    Directory of Open Access Journals (Sweden)

    Novrida Qudsi Lutfillah

    2014-08-01

    Full Text Available This article aims to uncover the accounting practices of Sĩma. The archaeological context is used as a research method to collect data, to interpret and to understand a culture. The results concluded that the accounting practices of sima had purposes to: (1 give privileges to certain areas; (2 establish and balanced the powers of social religious institution. The accounting practices and the role of the accountant (called Citralekha are visible on the ritual ceremonies of Sĩma. The values reflected in the accounting practice were the blessings and the peace of life, as well as the self purity.

  15. Stratigraphic-structural characteristics of Mačva basin

    Directory of Open Access Journals (Sweden)

    Carević Ivana

    2009-01-01

    Full Text Available The analysis of stratigraphic-structural features of Mačva basin had been conducted in this paper on the basis of data obtained with deep exploratory boring performed for the needs of hydrogeothermal research project for the purpose of identifying the reserves of geothermal energy of Mačva. The research has been carried out with the aim of finding out the relation between the Tertiary and its Triassic bedrock (Ladinian and Carnian stages in which process the considerable realistic image of paleorelief (the bedrock of Tertiary deposits was obtained.

  16. CPAPD Vice President Mr. Ma Biao Visits Morocco and Greece

    Institute of Scientific and Technical Information of China (English)

    2015-01-01

    At the respective invitation of the Amadeus Institute and the World Peace Council(WPC),Mr.Ma Biao,Vice Chairman of the National Committee of the Chinese People’s Political Consultative Conference(CPPCC)and Vice President of the Chinese People’s Association for Peace and Disarmament(CPAPD)led a CPAPD delegation on a good-will visit to Morocco and Greece during November 10 to 19,2015.During the stay in Morocco,Mr.Ma Biao respectively met with Moroccan Senate Vice

  17. DVD-d. Shrek Kolmas; Ma olen legend / Andres Laasik

    Index Scriptorium Estoniae

    Laasik, Andres, 1960-2016

    2008-01-01

    Lühiarvustused USA 2007.a. filmidele : animafilm "Shrek Kolmas" ("Shrek the Third", režissöörid Chris Miller, Raman Hui) ja ulmefilm "Ma olen legend" ("I Am Legend"; režissöör Francis Lawrence)

  18. Thesis Writing Challenges for Non-Native MA Students

    Science.gov (United States)

    Sadeghi, Karim; Shirzad Khajepasha, Arash

    2015-01-01

    Writing in a second (L2)/foreign language is generally a challenging activity, and writing an MA thesis, as an example of academic enterprise, can be daunting when done in a language in which the writer is not fully competent. The challenge such a genre of writing poses for L2 writers has not been properly addressed. To fill in the gap in this…

  19. Ma Shi Wen Tong and its Theory of Language

    Institute of Scientific and Technical Information of China (English)

    2007-01-01

    <正>Ma Shi Wen Tong is a very influential book in the field of linguistics.Its theory of language is closely related to the social background of China at that time.The paper will deal with concept of language in this book from a cultural and historical perspective.

  20. China's Overseas M&A in Global Economic Crisis

    Institute of Scientific and Technical Information of China (English)

    Han Kang

    2009-01-01

    @@ verseas Merger and Acquisition (M&A) is not only the major means for the enterprises to expand rapid-ly and operate globally, but also the significant stra-tegic tools for acquiring advanced technotegy from other companies and seizing the market and other resources.

  1. Ma Junren’s Track Team Stuns the World

    Institute of Scientific and Technical Information of China (English)

    1994-01-01

    At the Fourth World Athletics Championships in Stuttgart, Germany, Chinese runners, most Ma Junren’s, triumphed. They won the gold in the 1,500, gold and silver in the 10,000 and swept the 3,000. Twenty-four days later at the National Games in Beijing, Ma’s team broke many world records.

  2. Organisational Learning through International M&A Integration Strategies

    Science.gov (United States)

    Holland, Wayne; Salama, Alzira

    2010-01-01

    Purpose: The purpose of this research paper is to explore the learning process associated with international mergers and acquisitions (M&A) integration strategies. Design/methodology/approach: The paper employs a comparative case study methodology, utilising qualitative data through in-depth interviews with top management responsible for…

  3. 75 FR 65567 - Drawbridge Operation Regulations; Mystic River, Charlestown, MA

    Science.gov (United States)

    2010-10-26

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF HOMELAND SECURITY Coast Guard 33 CFR Part 117 Drawbridge Operation Regulations; Mystic River, Charlestown, MA AGENCY: Coast Guard, DHS. ACTION: Notice of temporary deviation from regulations. SUMMARY: The Commander,...

  4. 75 FR 25305 - Massachusetts Disaster Number MA-00027

    Science.gov (United States)

    2010-05-07

    ... From the Federal Register Online via the Government Publishing Office SMALL BUSINESS ADMINISTRATION Massachusetts Disaster Number MA-00027 AGENCY: U.S. Small Business Administration. ACTION: Amendment 1. SUMMARY: This is an amendment of the Presidential declaration of a major disaster for...

  5. 75 FR 25305 - Massachusetts Disaster Number MA-00025

    Science.gov (United States)

    2010-05-07

    ... From the Federal Register Online via the Government Publishing Office SMALL BUSINESS ADMINISTRATION Massachusetts Disaster Number MA-00025 AGENCY: U.S. Small Business Administration. ACTION: Amendment 1. SUMMARY: This is an amendment of the Presidential declaration of a major disaster for...

  6. 76 FR 58558 - Massachusetts Disaster Number MA-00040

    Science.gov (United States)

    2011-09-21

    ... From the Federal Register Online via the Government Publishing Office ] SMALL BUSINESS ADMINISTRATION Massachusetts Disaster Number MA-00040 AGENCY: U.S. Small Business Administration. ACTION: Amendment 1. SUMMARY: This is an amendment of the Presidential declaration of a major disaster for...

  7. 78 FR 37455 - Drawbridge Operation Regulations; Charles River, Boston, MA

    Science.gov (United States)

    2013-06-21

    ... regulation was published in the Federal Register (78 FR 35756) under the same name and docket number. This... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF HOMELAND SECURITY Coast Guard 33 CFR Part 117 Drawbridge Operation Regulations; Charles River, Boston, MA...

  8. 77 FR 6963 - Drawbridge Operation Regulations; Merrimack River, Amesbury, MA

    Science.gov (United States)

    2012-02-10

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF HOMELAND SECURITY Coast Guard 33 CFR Part 117 Drawbridge Operation Regulations; Merrimack River, Amesbury, MA AGENCY: Coast Guard, DHS. ACTION: Notice of temporary deviation from regulations. SUMMARY: The Commander,...

  9. 46 CFR 308.544 - Facultative binder, Form MA-315.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 8 2010-10-01 2010-10-01 false Facultative binder, Form MA-315. 308.544 Section 308.544 Shipping MARITIME ADMINISTRATION, DEPARTMENT OF TRANSPORTATION EMERGENCY OPERATIONS WAR RISK INSURANCE War Risk Cargo Insurance Iii-Facultative War Risk Cargo Insurance § 308.544 Facultative binder, Form...

  10. 46 CFR 308.533 - Closing report, Form MA-313.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 8 2010-10-01 2010-10-01 false Closing report, Form MA-313. 308.533 Section 308.533 Shipping MARITIME ADMINISTRATION, DEPARTMENT OF TRANSPORTATION EMERGENCY OPERATIONS WAR RISK INSURANCE War Risk Cargo Insurance Ii-Open Policy War Risk Cargo Insurance § 308.533 Closing report, Form...

  11. 76 FR 67245 - Massachusetts Disaster Number MA-00040

    Science.gov (United States)

    2011-10-31

    ... From the Federal Register Online via the Government Publishing Office SMALL BUSINESS ADMINISTRATION Disaster Declaration 12803 and 12804 Massachusetts Disaster Number MA-00040 AGENCY: U.S. Small Business Administration. ACTION: Amendment 2. SUMMARY: This is an amendment of the Presidential...

  12. 77 FR 65619 - Drawbridge Operation Regulations; Taunton River, MA

    Science.gov (United States)

    2012-10-30

    ... Federal Register (73 FR 3316). 4. Public Meeting We do not now plan to hold a public meeting. But you may... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF HOMELAND SECURITY Coast Guard 33 CFR Part 117 Drawbridge Operation Regulations; Taunton River, MA AGENCY:...

  13. 76 FR 45644 - Massachusetts Disaster Number MA-00037

    Science.gov (United States)

    2011-07-29

    ... From the Federal Register Online via the Government Publishing Office SMALL BUSINESS ADMINISTRATION Massachusetts Disaster Number MA-00037 AGENCY: U.S. Small Business Administration. ] ACTION: Amendment 1. SUMMARY: This is an amendment of the Presidential declaration of a major disaster for...

  14. 78 FR 35756 - Drawbridge Operation Regulations; Charles River, Boston, MA

    Science.gov (United States)

    2013-06-14

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF HOMELAND SECURITY Coast Guard 33 CFR Part 117 Drawbridge Operation Regulations; Charles River, Boston, MA AGENCY: Coast Guard, DHS. ACTION: Notice of temporary deviation from regulations. SUMMARY: The Commander,...

  15. 76 FR 53019 - Massachusetts Disaster Number MA-00036

    Science.gov (United States)

    2011-08-24

    ... From the Federal Register Online via the Government Publishing Office SMALL BUSINESS ADMINISTRATION Massachusetts Disaster Number MA-00036 AGENCY: U.S. Small Business Administration. ACTION: Amendment 1. SUMMARY: This is an amendment of the Presidential declaration of a major disaster for the...

  16. 75 FR 30872 - Massachusetts Disaster Number MA-00025

    Science.gov (United States)

    2010-06-02

    ... From the Federal Register Online via the Government Publishing Office SMALL BUSINESS ADMINISTRATION Massachusetts Disaster Number MA-00025 AGENCY: U.S. Small Business Administration. ACTION: Amendment 2. SUMMARY: This is an amendment of the Presidential declaration of a major disaster for the...

  17. 78 FR 15292 - Drawbridge Operation Regulations; West Bay, Osterville, MA

    Science.gov (United States)

    2013-03-11

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF HOMELAND SECURITY Coast Guard 33 CFR Part 117 Drawbridge Operation Regulations; West Bay, Osterville, MA AGENCY: Coast Guard, DHS. ACTION: Notice of temporary deviation from regulation. SUMMARY: The Coast Guard...

  18. 75 FR 39059 - Massachusetts Disaster Number MA-00025

    Science.gov (United States)

    2010-07-07

    ... From the Federal Register Online via the Government Publishing Office SMALL BUSINESS ADMINISTRATION Massachusetts Disaster Number MA-00025 AGENCY: U.S. Small Business Administration. ACTION: Amendment 3. SUMMARY: This is an amendment of the Presidential declaration of a major disaster for...

  19. DVD-d. Shrek Kolmas; Ma olen legend / Andres Laasik

    Index Scriptorium Estoniae

    Laasik, Andres, 1960-2016

    2008-01-01

    Lühiarvustused USA 2007.a. filmidele : animafilm "Shrek Kolmas" ("Shrek the Third", režissöörid Chris Miller, Raman Hui) ja ulmefilm "Ma olen legend" ("I Am Legend"; režissöör Francis Lawrence)

  20. Thesis Writing Challenges for Non-Native MA Students

    Science.gov (United States)

    Sadeghi, Karim; Shirzad Khajepasha, Arash

    2015-01-01

    Writing in a second (L2)/foreign language is generally a challenging activity, and writing an MA thesis, as an example of academic enterprise, can be daunting when done in a language in which the writer is not fully competent. The challenge such a genre of writing poses for L2 writers has not been properly addressed. To fill in the gap in this…

  1. MaRGEE: Move and Rotate Google Earth Elements

    Science.gov (United States)

    Dordevic, Mladen M.; Whitmeyer, Steven J.

    2015-12-01

    Google Earth is recognized as a highly effective visualization tool for geospatial information. However, there remain serious limitations that have hindered its acceptance as a tool for research and education in the geosciences. One significant limitation is the inability to translate or rotate geometrical elements on the Google Earth virtual globe. Here we present a new JavaScript web application to "Move and Rotate Google Earth Elements" (MaRGEE). MaRGEE includes tools to simplify, translate, and rotate elements, add intermediate steps to a transposition, and batch process multiple transpositions. The transposition algorithm uses spherical geometry calculations, such as the haversine formula, to accurately reposition groups of points, paths, and polygons on the Google Earth globe without distortion. Due to the imminent deprecation of the Google Earth API and browser plugin, MaRGEE uses a Google Maps interface to facilitate and illustrate the transpositions. However, the inherent spatial distortions that result from the Google Maps Web Mercator projection are not apparent once the transposed elements are saved as a KML file and opened in Google Earth. Potential applications of the MaRGEE toolkit include tectonic reconstructions, the movements of glaciers or thrust sheets, and time-based animations of other large- and small-scale geologic processes.

  2. BioMaPS: A Roadmap for Success

    Science.gov (United States)

    McCarthy, Maeve L.; Fister, K. Renee

    2010-01-01

    The manuscript outlines the impact that our National Science Foundation Interdisciplinary Training for Undergraduates in Biological and Mathematical Sciences program, BioMaPS, has had on the students and faculty at Murray State University. This interdisciplinary program teams mathematics and biology undergraduate students with mathematics and…

  3. 42 CFR 422.74 - Disenrollment by the MA organization.

    Science.gov (United States)

    2010-10-01

    ...) Basis of disenrollment for disruptive behavior. An organization may disenroll an individual whose... MA organization has fulfilled the requirements to request disenrollment for disruptive behavior. If... established under paragraph (d)(1) of this section. (ii) The individual has engaged in disruptive...

  4. The Authority and Charismas of Jack Ma's Leadership

    Institute of Scientific and Technical Information of China (English)

    陈希

    2014-01-01

    Jack Ma is the top manager of Ali Baba group, with a strong leadership. He mixes autocratic leadership and charismatic leadership together. The powers he used are from his position, the reward system of the company and the charismas to gain his leading power. In addition, he uses his charismas and his achievements to win the trust of the employees, which develop his leadership.

  5. M&A New Rules May Trigger Merger Wave

    Institute of Scientific and Technical Information of China (English)

    HUBERT TSE

    2006-01-01

    @@ The Chinese government issued a series of new M&A and takeover rules in July and August 2006 to further regulate and facilitate foreign investors' acquisition activities in China.The new rules are aimed at offering more flexibility, reducing costs and increasing takeover efficiencies for foreign-funded M&As in the world's fastest-growing major economy.

  6. 42 CFR 422.104 - Special rules on supplemental benefits for MA MSA plans.

    Science.gov (United States)

    2010-10-01

    ... 42 Public Health 3 2010-10-01 2010-10-01 false Special rules on supplemental benefits for MA MSA... Beneficiary Protections § 422.104 Special rules on supplemental benefits for MA MSA plans. (a) An MA organization offering an MA MSA plan may not provide supplemental benefits that cover expenses that...

  7. Studies of MaPMTs with beetle-chip read-out

    CERN Document Server

    Muheim, F

    2005-01-01

    We have evaluated the 64-channel Multianode Photo-Multiplier (MaPMT) with 8-stage dynodes for the LHCb RICH detectors. With a Beetle1.2 chip to read-out the MaPMT, we have demonstrated that the MaPMT performance is as expected using particle beams and LED light sources. We have also measured the pulse shape from 12-stage dynode MaPMTs, read out with the Beetle1.2-MA0 chip.

  8. Studies of MaPMTs with beetle-chip read-out

    CERN Document Server

    Muheim, F

    2005-01-01

    We have evaluated the 64-channel Multianode Photo-Multiplier (MaPMT) with 8-stage dynodes for the LHCb RICH detectors. With a Beetle 1.2 chip to read-out the MaPMT, we have demonstrated that the MaPMT performance is as expected using particle beams and LED light sources. We have also measured the pulse shape from 12-stage dynode MaPMTs, read out with the Beetle 1.2-MA0 chip.

  9. Cell-laden photocrosslinked GelMA-DexMA copolymer hydrogels with tunable mechanical properties for tissue engineering.

    Science.gov (United States)

    Wang, Hang; Zhou, Lei; Liao, Jingwen; Tan, Ying; Ouyang, Kongyou; Ning, Chenyun; Ni, Guoxin; Tan, Guoxin

    2014-09-01

    To effectively repair or replace damaged tissues, it is necessary to design three dimensional (3D) extracellular matrix (ECM) mimicking scaffolds with tunable biomechanical properties close to the desired tissue application. In the present work, gelatin methacrylate (GelMA) and dextran glycidyl methacrylate (DexMA) with tunable mechanical and biological properties were utilized to prepared novel bicomponent polymeric hydrogels by cross-linking polymerization using photoinitiation. We controlled the degree of substitution (DS) of glycidyl methacrylate in DexMA so that they could obtain relevant mechanical properties. The results indicated that copolymer hydrogels demonstrated a lower swelling ratio and higher compressive modulus as compared to the GelMA. Moreover, all of the hydrogels exhibited a honeycomb-like architecture, the pore sizes decreased as DS increased, and NIH-3T3 fibroblasts encapsulated in these hydrogels all exhibited excellent viability. These characteristics suggest a class of photocrosslinkable, tunable mechanically copolymer hydrogels that may find potential application in tissue engineering and regenerative medicine applications.

  10. El concepto pneûma en el Anonymus Londinensis

    Directory of Open Access Journals (Sweden)

    Crespo Saumell, Jordi

    2014-12-01

    Full Text Available This article has chiefly to do with a Greek concept especially subject to overlap in meaning: pneûma. Translated into Latin as ‘spiritus’, pneûma is a unique term doubtlessly accounting for the handful of ideas grounding Western tradition. Pneûma’s former significations look to be substantially different to the major one with which the term has come down and stands for the time being. Hence, it seems worthwhile enquiring into its origins in ancient scientific literature. In order to do so, the papyrus called Anonymus Londinensis, a master piece in the History of Medicine, will be examined and put alongside Aristotle’s biological views. Attention is therefore focused on the occurrences of pneûma in the papyrus, its different meanings when contrasted to cognate terms like ‘phŷsa’ or ‘air’, as well as the special way that very term may have displayed by the different physicians reported in the document.El presente artículo versa sobre un término griego especialmente sujeto a la polisemia: pneûma. Traducido al latín como ‘spiritus’, pneûma es uno de los conceptos que, sin duda, se encuentra en la base y ha conformado la tradición especulativa occidental. Dado que los primeros significados de pneûma parecen substancialmente distintos al sentido mayoritario y general por el que se lo tiene en la actualidad, parece conveniente indagar su uso en la literatura científica griega. Para ello se estudia su empleo en el seno de una de las obras claves de la Historia de la Medicina, el llamado papiro Anonymus Londinensis, y se contrasta con la biología griega del s. IV a.C. tal y como se encuentra en los Parva Naturalia de Aristóteles. La atención, por tanto, se centra en el uso y significado del término en dicho papiro, su significado particular cuando se lo compara con algunos términos afines como ‘phŷsa’ o ‘aire’, así como el modo especial con el que lo usan los diferentes médicos de los que el papiro da

  11. Reflexiones sobre la identidad en Macunaíma

    Directory of Open Access Journals (Sweden)

    Gessica Giohanna Espejo Velásquez

    2013-01-01

    Full Text Available Este artículo de reflexión es una aproximación a la problemática de identidad existente dentro de la novela Macunaíma de Mario de Andrade. Abordaré dicha temática a partir de los planteamientos de Fernando Ortiz y Leopoldo Zea; planteamientos que se configuran en tres personajes que dentro de la obra cumplen un papel primordial para comprender la propuesta del escritor brasilero. Estos son: Macunaíma, Venceslao Pietro Pietra y las Icamiabas. De este modo, analizo diferentes fragmentos de la novela con el fin de evidenciar ese afán por reconocer y reafirmar la identidad del hombre brasilero.

  12. Traditional Confucianism in modern China:Ma Yifu's ethical thought

    Institute of Scientific and Technical Information of China (English)

    Chai Wenhua

    2006-01-01

    Modern neo-Confucianism is studied at two levels,one is at the historical level and the other at the academic level.Modern neo-Confucianism at the historical level was developed in the modern context,but its basic content belongs to the traditional Confucianism or the study of Confucian classics.Modern neo-Confucianism at the academic level recognizes both the deficiencies of the traditional Confucianism and rationality of western learning,and dedicates itself to the modernization of Confucianism.Though Ma Yifu's moral philosophy is developed in the context of modern Chinese culture,it fails to deal with the problem of modern transformation of Confucian ethical values and its content still belongs to the traditional Confucianism.So it should be labeled as the modern neo-Confucianism in the historical sense.In this Paper,the author makes a systematic exploration and an evaluation of Ma Yifu's ethical thought.

  13. Experimental Physical Sciences Vistas: MaRIE (draft)

    Energy Technology Data Exchange (ETDEWEB)

    Shlachter, Jack [Los Alamos National Laboratory

    2010-09-08

    To achieve breakthrough scientific discoveries in the 21st century, a convergence and integration of world-leading experimental facilities and capabilities with theory, modeling, and simulation is necessary. In this issue of Experimental Physical Sciences Vistas, I am excited to present our plans for Los Alamos National Laboratory's future flagship experimental facility, MaRIE (Matter-Radiation Interactions in Extremes). MaRIE is a facility that will provide transformational understanding of matter in extreme conditions required to reduce or resolve key weapons performance uncertainties, develop the materials needed for advanced energy systems, and transform our ability to create materials by design. Our unique role in materials science starting with the Manhattan Project has positioned us well to develop a contemporary materials strategy pushing the frontiers of controlled functionality - the design and tailoring of a material for the unique demands of a specific application. Controlled functionality requires improvement in understanding of the structure and properties of materials in order to synthesize and process materials with unique characteristics. In the nuclear weapons program today, improving data and models to increase confidence in the stockpile can take years from concept to new knowledge. Our goal with MaRIE is to accelerate this process by enhancing predictive capability - the ability to compute a priori the observables of an experiment or test and pertinent confidence intervals using verified and validated simulation tools. It is a science-based approach that includes the use of advanced experimental tools, theoretical models, and multi-physics codes, simultaneously dealing with multiple aspects of physical operation of a system that are needed to develop an increasingly mature predictive capability. This same approach is needed to accelerate improvements to other systems such as nuclear reactors. MaRIE will be valuable to many national

  14. Cosmological bounds in MaVaN models

    Energy Technology Data Exchange (ETDEWEB)

    Boriero, D.F.; Holanda, P.C. de [Instituto de Fisica ' Gleb Wataghin' , Universidade Estadual de Campinas, UNICAMP, 13083-859, Campinas, Sao Paulo (Brazil)

    2012-08-15

    Mass varying neutrino (MaVaN) is a class of models which in cosmology try to explain the coincidence of dark energy density through a tracking mechanism related with neutrinos. This special model couples the quintessential scalar field with neutrino generating an effective mass which becomes variable. Furthermore, it has been shown that an additional coupling among the quintessential field and baryons could generate specific dependences of neutrino mass with baryonic density.

  15. Portraits de Maîtres offerts à Olga Weijers

    NARCIS (Netherlands)

    Teeuwen, M.J.; Angotti, C.; Brînzei, M.

    2013-01-01

    En 2011, le répertoire d’Olga Weijers, Le travail intellectuel à la faculté des arts de Paris : textes et maîtres (ca. 1200-1500), en neuf volumes, est arrivé à son terme. Cet instrument de travail a également inauguré la collection Studia Artistarum dans laquelle Olga Weijers a accueilli ces quinze

  16. Summary of ST-MA deliverables for LHC

    CERN Document Server

    Cennini, E; Ninin, P; Nunes, R; Scibile, L; CERN. Geneva. ST Division

    2003-01-01

    The ST/MA group is responsible for the monitoring of the CERN Technical Infrastructure as well as the design, installation and maintenance of personnel protection system such as access control system, fire and gas leak detection, safety alarm monitoring systems and radiation monitoring systems (in collaboration with TIS). This paper provides an overview of the main projects and services managed in the group and outlines the scope, the organisation and the planning of the main deliverables for LHC.

  17. Ma Xinlan Reflects on a 23-year Teaching Career

    Institute of Scientific and Technical Information of China (English)

    1994-01-01

    SHE wears a white cap typically worn by women of the Hui ethnic nationality and a smile which often appears on her amiable face. And when the smile comes, her face betrays the races years left on it, which leads me to believe that she doesn’t live a relaxed life. She is Ma Xinlan, 42, principal of the Weizhou Hui Nationality Girls Primary School in Ningxia Hui Nationality Autonomous Region.

  18. Design of a 500 MJ, 5 MA power supply

    Science.gov (United States)

    Pappas, J. A.; Headifen, G. R.; Weldon, J. M.; Wright, J. C.; Zowarka, R. C.; Aanstoos, T. A.; Kajs, J. H.

    1993-01-01

    The design of a 500 MJ, 5 MA power supply for rail gun experiments under the Battery Upgraded Supply (BUS) program is examined. About 50,000 12-volt lead acid batteries are required to reach this level. BUS will be required to perform up to two discharges per week. Therefore, BUS is designed to be a low-maintenance, reliable, and fault-tolerant power supply. The design of BUS and the details of its subsystems are described.

  19. The tectonic structure of the Song Ma fault zone, Vietnam

    Science.gov (United States)

    Wen, Strong; Yeh, Yu-Lien; Tang, Chi-Cha; Phong, Lai Hop; Toan, Dinh Van; Chang, Wen-Yen; Chen, Chau-Huei

    2015-08-01

    Indochina area is a tectonic active region where creates complex topographies and tectonic structures. In particular, the Song Ma fault zone plays an important role in understanding the mechanism and revolution of the collision between the Indian plate and Eurasian plate. In order to have better understanding the seismotectonic structures of the Song Ma fault zone, a three-year project is proposed to study the seismotectonic structures of crust in this region. The main goal of this project is to deploy temporary broad-band seismic stations around/near the shear zone to record high quality microearthquakes. By using the data recorded by the temporary array and the local seismic network, we are able to conduct seismological studies which include using waveform inversion to obtain precise fault plane solutions of microearthquakes, one-dimensional (1-D) velocity structure of the crust in the region as well as the characteristics of seismogeneric zone. From the results of earthquake relocation and focal mechanisms, we find that the spatial distribution of events occurred in Song Ma fault zone forms in several distinct groups which are well correlated local geological structures and further use to gain insights on tectonic evolution.

  20. SCHeMA web-based observation data information system

    Science.gov (United States)

    Novellino, Antonio; Benedetti, Giacomo; D'Angelo, Paolo; Confalonieri, Fabio; Massa, Francesco; Povero, Paolo; Tercier-Waeber, Marie-Louise

    2016-04-01

    It is well recognized that the need of sharing ocean data among non-specialized users is constantly increasing. Initiatives that are built upon international standards will contribute to simplify data processing and dissemination, improve user-accessibility also through web browsers, facilitate the sharing of information across the integrated network of ocean observing systems; and ultimately provide a better understanding of the ocean functioning. The SCHeMA (Integrated in Situ Chemical MApping probe) Project is developing an open and modular sensing solution for autonomous in situ high resolution mapping of a wide range of anthropogenic and natural chemical compounds coupled to master bio-physicochemical parameters (www.schema-ocean.eu). The SCHeMA web system is designed to ensure user-friendly data discovery, access and download as well as interoperability with other projects through a dedicated interface that implements the Global Earth Observation System of Systems - Common Infrastructure (GCI) recommendations and the international Open Geospatial Consortium - Sensor Web Enablement (OGC-SWE) standards. This approach will insure data accessibility in compliance with major European Directives and recommendations. Being modular, the system allows the plug-and-play of commercially available probes as well as new sensor probess under development within the project. The access to the network of monitoring probes is provided via a web-based system interface that, being implemented as a SOS (Sensor Observation Service), is providing standard interoperability and access tosensor observations systems through O&M standard - as well as sensor descriptions - encoded in Sensor Model Language (SensorML). The use of common vocabularies in all metadatabases and data formats, to describe data in an already harmonized and common standard is a prerequisite towards consistency and interoperability. Therefore, the SCHeMA SOS has adopted the SeaVox common vocabularies populated by

  1. Neuroprotective Effect of Gui Zhi (Ramulus Cinnamomi on Ma Huang- (Herb Ephedra- Induced Toxicity in Rats Treated with a Ma Huang-Gui Zhi Herb Pair

    Directory of Open Access Journals (Sweden)

    Fang-hao Zheng

    2015-01-01

    Full Text Available Herb Ephedra (Ma Huang in Chinese and Ramulus Cinnamomi (Gui Zhi in Chinese are traditional Chinese herbs, often used together to treat asthma, nose and lung congestion, and fever with anhidrosis. Due to the adverse effects of ephedrine, clinical use of Ma Huang is restricted. However, Gui Zhi extract has been reported to decrease spontaneous activity in rats and exert anti-inflammatory and neuroprotective effects. The present study explored the possible inhibitory effect of Gui Zhi on Ma Huang-induced neurotoxicity in rats when the two herbs were used in combination. All Ma Huang and Ma Huang-Gui Zhi herb pair extracts were prepared using methods of traditional Chinese medicine and were normalized based on the ephedrine content. Two-month-old male Sprague-Dawley rats (n=6 rats/group were administered Ma Huang or the Ma Huang-Gui Zhi herb pair extracts for 7 days (ephedrine = 48 mg/kg, and locomotor activity was measured. After 7 days, oxidative damage in the prefrontal cortex was measured. Gui Zhi decreased hyperactivity and sensitization produced by repeated Ma Huang administration and attenuated oxidative stress induced by Ma Huang. The results of this study demonstrate the neuroprotective potential of Gui Zhi in Ma Huang-induced hyperactivity and oxidative damage in the prefrontal cortex of rats when used in combination.

  2. Neuroprotective effect of gui zhi (ramulus cinnamomi) on ma huang- (herb ephedra-) induced toxicity in rats treated with a ma huang-gui zhi herb pair.

    Science.gov (United States)

    Zheng, Fang-Hao; Wei, Ping; Huo, Hui-Ling; Xing, Xue-Feng; Chen, Fei-Long; Tan, Xiao-Mei; Luo, Jia-Bo

    2015-01-01

    Herb Ephedra (Ma Huang in Chinese) and Ramulus Cinnamomi (Gui Zhi in Chinese) are traditional Chinese herbs, often used together to treat asthma, nose and lung congestion, and fever with anhidrosis. Due to the adverse effects of ephedrine, clinical use of Ma Huang is restricted. However, Gui Zhi extract has been reported to decrease spontaneous activity in rats and exert anti-inflammatory and neuroprotective effects. The present study explored the possible inhibitory effect of Gui Zhi on Ma Huang-induced neurotoxicity in rats when the two herbs were used in combination. All Ma Huang and Ma Huang-Gui Zhi herb pair extracts were prepared using methods of traditional Chinese medicine and were normalized based on the ephedrine content. Two-month-old male Sprague-Dawley rats (n = 6 rats/group) were administered Ma Huang or the Ma Huang-Gui Zhi herb pair extracts for 7 days (ephedrine = 48 mg/kg), and locomotor activity was measured. After 7 days, oxidative damage in the prefrontal cortex was measured. Gui Zhi decreased hyperactivity and sensitization produced by repeated Ma Huang administration and attenuated oxidative stress induced by Ma Huang. The results of this study demonstrate the neuroprotective potential of Gui Zhi in Ma Huang-induced hyperactivity and oxidative damage in the prefrontal cortex of rats when used in combination.

  3. MaLDA:medication analysis based on LDA%MaLDA:基于LDA的用药分析

    Institute of Scientific and Technical Information of China (English)

    周靖; 佘玉轩; 熊赟

    2016-01-01

    为了给医生及病人安全、合理、高效用药提供决策支持,提出了一种基于LDA(Latent Dirichlet Allocation)的用药分析方法MaLDA(Medication Analysis based on LDA)。该方法结合了用药记录和就诊记录,将药物看作文档、药物功能看作主题、疾病看作词语,通过主题模型LDA发现隐含的药物功能,通过药物功能,将相关药物、相关疾病和药物与疾病联系起来。根据药物对药物功能的分布对药物进行聚类,每一类药物被相关的疾病所描述,进而对临床用药进行分析。MaLDA不仅能发现临床用药中针对某一类疾病效用较好的药物,而且能发现隐含的联合用药。实验数据来源于上海市某医院137510位病人的用药记录和就诊记录。实验结果证实了MaLDA相对于其他方法在对电子就医记录进行用药分析的有效性。%To provide support for doctors and patients to use drugs in a safer, more rational and efficient way, this paper proposes a framework for medication analysis based on LDA(Latent Dirichlet Allocation), MaLDA(Medication Analysis based on the LDA). MaLDA combines the usage of medication records and diagnostic records, infers the function of each drug using topic-based inference model LDA, which regards a drug as a document, a function as a topic, and a disease as a word. As a result, related drugs, drug and disease, related diseases are associated by functions. Then clustering all drugs according to its distribution of functions, and each cluster is described by related diseases. Finally, it analyzes the clinical medication based on the results of clustering. The result generated by MaLDA can not only find the drug which is better in treatment, but also find the drug combination which lays the foundation for mining drug side effects and the complications of disease. The method is evaluated by using 137 510 patients’diagnostic records and medication records. The results justify

  4. Astronaut Scott Carpenter being recovered from Ocean after MA-7 flight

    Science.gov (United States)

    1962-01-01

    Astronaut M. Scott Carpenter, prime pilot for the Mercury-Atlas 7 (MA-7) mission, is seen being recovered from Atlantic Ocean after MA-7 flight. A diver helps Carpenter into a life raft while the capsule floats nearby.

  5. 75 FR 61096 - Regulated Navigation Area; Reserved Channel, Boston Harbor, Boston, MA

    Science.gov (United States)

    2010-10-04

    ... Harbor, Boston, MA AGENCY: Coast Guard, DHS. ACTION: Temporary final rule. SUMMARY: The Coast Guard is... Navigation Areas: Reserved Channel, Boston Harbor, Boston, MA (a) Location. The following areas are...

  6. 77 FR 22611 - Cape Cod National Seashore Advisory Commission; Cape Cod National Seashore, South Wellfleet, MA

    Science.gov (United States)

    2012-04-16

    ... Wellfleet, MA AGENCY: National Park Service, Interior. ACTION: Two Hundred Eighty-Fourth Notice of Meeting..., Wellfleet, MA 02667. Dated: April 9, 2012. George E. Price, Jr., Superintendent. BILLING CODE 4310-WV-P...

  7. 42 CFR 495.206 - Timeframe for payment to qualifying MA organizations.

    Science.gov (United States)

    2010-10-01

    ... organizations for qualifying MA-affiliated eligible hospitals under common corporate governance are made under... common corporate governance under the Medicare FFS EHR incentive program, payment is made under the MA...

  8. Diätetische Maßnahmen bei Prostatakarzinom

    Directory of Open Access Journals (Sweden)

    Hübner W

    2001-01-01

    Full Text Available Der Einfluß diätetischer Gewohnheiten und Maßnahmen auf Krebserkrankungen und im speziellen auf das Entstehen eines Prostatakarzinoms haben im vergangenen Jahr auch in Europa große Publizität gewonnen. Es ist unsere Aufgabe als Urologen, auch auf diesem Gebiet kompetente Hilfestellung für unsere Patienten zu bieten. In der Folge möchte ich kurz auf Möglichkeiten, Grenzen und Indikationen diätetischer Maßnahmen beim Prostatakarzinom eingehen. Der Zusammenhang zwischen diätetischen Maßnahmen und klinischem Entstehen eines Prostatakarzinoms ist uns aus den sogenannten Emigrantenstudien bekannt. So konnte festgestellt werden, daß das Verhältnis der Prostatakrebsentstehung zwischen Japanern und weißen Amerikanern 1:5 beträgt, sich aber bei Japanern, die in 2. Generation in Amerika leben, gegenüber den weißen Amerikanern auf 1:1 verändert. Von den verschiedenen Umweltfaktoren und Lebensgewohnheiten werden in erster Linie Änderungen der Eßgewohnheiten nach der Emigration dafür verantwortlich gemacht. Der Einfluß verschiedener Eßgewohnheiten auf die Karzinomentstehung wurde in der Vergangenheit nicht nur von Naturheilern und Komplementärmedizinern angesprochen, in mehr als 1500 Artikeln zum Thema "Krebs und Diät" wurde diese Thematik in den vergangenen 2 Jahren auch in den Standard- und Topjournals der medizinischen Fachliteratur behandelt. Informationen zu den wichtigsten Diätinhaltsstoffen möchte ich hier zusammenfassen.

  9. SDSS-IV/MaNGA: Spectrophotometric Calibration Technique

    Science.gov (United States)

    Yan, Renbin; Tremonti, Christy; Bershady, Matthew A.; Law, David R.; Schlegel, David J.; Bundy, Kevin; Drory, Niv; MacDonald, Nicholas; Bizyaev, Dmitry; Blanc, Guillermo A.; Blanton, Michael R.; Cherinka, Brian; Eigenbrot, Arthur; Gunn, James E.; Harding, Paul; Hogg, David W.; Sánchez-Gallego, José R.; Sánchez, Sebastian F.; Wake, David A.; Weijmans, Anne-Marie; Xiao, Ting; Zhang, Kai

    2016-01-01

    Mapping Nearby Galaxies at Apache Point Observatory (MaNGA), one of three core programs in the Sloan Digital Sky Survey-IV, is an integral-field spectroscopic survey of roughly 10,000 nearby galaxies. It employs dithered observations using 17 hexagonal bundles of 2″ fibers to obtain resolved spectroscopy over a wide wavelength range of 3600-10300 Å. To map the internal variations within each galaxy, we need to perform accurate spectral surface photometry, which is to calibrate the specific intensity at every spatial location sampled by each individual aperture element of the integral field unit. The calibration must correct only for the flux loss due to atmospheric throughput and the instrument response, but not for losses due to the finite geometry of the fiber aperture. This requires the use of standard star measurements to strictly separate these two flux loss factors (throughput versus geometry), a difficult challenge with standard single-fiber spectroscopy techniques due to various practical limitations. Therefore, we developed a technique for spectral surface photometry using multiple small fiber-bundles targeting standard stars simultaneously with galaxy observations. We discuss the principles of our approach and how they compare to previous efforts, and we demonstrate the precision and accuracy achieved. MaNGA's relative calibration between the wavelengths of Hα and Hβ has an rms of 1.7%, while that between [N ii] λ6583 and [O ii] λ3727 has an rms of 4.7%. Using extinction-corrected star formation rates and gas-phase metallicities as an illustration, this level of precision guarantees that flux calibration errors will be sub-dominant when estimating these quantities. The absolute calibration is better than 5% for more than 89% of MaNGA's wavelength range.

  10. SDSS-IV/MaNGA: SPECTROPHOTOMETRIC CALIBRATION TECHNIQUE

    Energy Technology Data Exchange (ETDEWEB)

    Yan, Renbin; Sánchez-Gallego, José R. [Department of Physics and Astronomy, University of Kentucky, 505 Rose St., Lexington, KY 40506-0057 (United States); Tremonti, Christy; Bershady, Matthew A.; Eigenbrot, Arthur; Wake, David A. [Department of Astronomy, University of Winsconsin-Madison, 475 N. Charter Street, Madison, WI 53706-1582 (United States); Law, David R. [Space Telescope Science Institute, 3700 San Martin Drive, Baltimore, MD 21218 (United States); Schlegel, David J. [Physics Division, Lawrence Berkeley National Laboratory, Berkeley, CA 94720-8160 (United States); Bundy, Kevin [Kavli IPMU (WPI), UTIAS, The University of Tokyo, Kashiwa, Chiba 277-8583 (Japan); Drory, Niv [McDonald Observatory, Department of Astronomy, University of Texas at Austin, 1 University Station, Austin, TX 78712-0259 (United States); MacDonald, Nicholas [Department of Astronomy, Box 351580, University of Washington, Seattle, WA 98195 (United States); Bizyaev, Dmitry [Apache Point Observatory, P.O. Box 59, sunspot, NM 88349 (United States); Blanc, Guillermo A. [Departamento de Astronomía, Universidad de Chile, Camino el Observatorio 1515, Las Condes, Santiago (Chile); Blanton, Michael R.; Hogg, David W. [Center for Cosmology and Particle Physics, Department of Physics, New York University, 4 Washington Place, New York, NY 10003 (United States); Cherinka, Brian [Dunlap Institute for Astronomy and Astrophysics, University of Toronto, 50 St. George Street, Toronto, Ontario M5S 3H4 (Canada); Gunn, James E. [Department of Astrophysical Sciences, Princeton University, Princeton, NJ 08544 (United States); Harding, Paul [Department of Astronomy, Case Western Reserve University, Cleveland, OH 44106 (United States); Sánchez, Sebastian F., E-mail: yanrenbin@uky.edu [Instituto de Astronomia, Universidad Nacional Autonoma de Mexico, A.P. 70-264, 04510 Mexico D.F. (Mexico); and others

    2016-01-15

    Mapping Nearby Galaxies at Apache Point Observatory (MaNGA), one of three core programs in the Sloan Digital Sky Survey-IV, is an integral-field spectroscopic survey of roughly 10,000 nearby galaxies. It employs dithered observations using 17 hexagonal bundles of 2″ fibers to obtain resolved spectroscopy over a wide wavelength range of 3600–10300 Å. To map the internal variations within each galaxy, we need to perform accurate spectral surface photometry, which is to calibrate the specific intensity at every spatial location sampled by each individual aperture element of the integral field unit. The calibration must correct only for the flux loss due to atmospheric throughput and the instrument response, but not for losses due to the finite geometry of the fiber aperture. This requires the use of standard star measurements to strictly separate these two flux loss factors (throughput versus geometry), a difficult challenge with standard single-fiber spectroscopy techniques due to various practical limitations. Therefore, we developed a technique for spectral surface photometry using multiple small fiber-bundles targeting standard stars simultaneously with galaxy observations. We discuss the principles of our approach and how they compare to previous efforts, and we demonstrate the precision and accuracy achieved. MaNGA's relative calibration between the wavelengths of Hα and Hβ has an rms of 1.7%, while that between [N ii] λ6583 and [O ii] λ3727 has an rms of 4.7%. Using extinction-corrected star formation rates and gas-phase metallicities as an illustration, this level of precision guarantees that flux calibration errors will be sub-dominant when estimating these quantities. The absolute calibration is better than 5% for more than 89% of MaNGA's wavelength range.

  11. Precise Asymptotics in Chung's Law of the Iterated Logarithm

    Institute of Scientific and Technical Information of China (English)

    Li Xin ZHANG

    2008-01-01

    Let X, X1, X2, . . . be i.i.d. random variables with mean zero and positive, finite variance σ2, and set Sn = X1 + . . . + Xn, n ≥ 1. The author proves that, if EX2I{|X| ≥ t} = o((log log t)-1) as t→∞, then for any a > -1 and b > -1, lim __1/√1+a_ 1 √1 + a . __b+1 ∞ _n=1 (log n)a(log log n)b n P_max k≤n |Sk| ≤ _ σ2π2n 8 log log n (_ + an)_ = 4 π_ 1 2(1 + a)3/2 _b+1 Γ(b + 1), whenever an = o(1/ log log n). The author obtains the sufficient and necessary conditions for this kind of results to hold.

  12. NASA JSC EV2 Intern Spring 2016 - Jennie Chung

    Science.gov (United States)

    Chung, Jennie

    2016-01-01

    Exploration Mission 2 (EM-2) is a mission to resume the manned exploration of the Solar System. This mission is the first crewed mission of NASA’s Orion on the Space Launch System. The target for EM-2 is to perform a flyby of a captured asteroid in lunar orbit, which NASA plans to launch in 2023. As an intern working with EV-2 – Avionics Systems Division in Johnson Space Center, we are developing flight instrumentation systems for EM-2 (MISL & RFID). The Modular Integrated Stackable Layer (MISL) is a compact space-related computer system that is modular, scalable and reconfigurable. The RFID (radio frequency identification) sensors are used to take lower frequency (TC) type measurements and be able to stream data real-time to an RF (radio frequency) interrogator upon demand. Our job, in EV-2, is to certify, test, manufacture/assemble and deliver flight EM-2 DFI System (MISL & RFID). Our goal is to propose a development effort to design low-mass wire and wireless data acquisition and sensor solutions for EM-2 DFI (Development Flight Instrumentation). The team is tasked to provide the most effective use of 75 pounds to acquire DFI data and to collect sensor data for 100-200 high priority DFI channels (mass driven).

  13. SelMa - Self-guided Learning in Teaching Mathematics

    Directory of Open Access Journals (Sweden)

    Wolfgang WEBER

    2004-04-01

    Full Text Available In the project ``Self-guided Learning in Teaching Mathematics - SEC II'' (SelMa, five authoring schools are working out scenarios, media and materials for phases of self-guided learning, which will be tested systematically by 10 trial schools with regard to their everyday suitability. In this paper three approaches to such learning arrangements (independent learning centre, jigsaw classroom and learning at stations are being outlined and relevant experiences are being made available. Learning diaries prove to be useful for the learners' reflection of their learning process. The development as well as the management of such learning arrangements does place new demands on the teachers.

  14. Advanced Query and Data Mining Capabilities for MaROS

    Science.gov (United States)

    Wang, Paul; Wallick, Michael N.; Allard, Daniel A.; Gladden, Roy E.; Hy, Franklin H.

    2013-01-01

    The Mars Relay Operational Service (MaROS) comprises a number of tools to coordinate, plan, and visualize various aspects of the Mars Relay network. These levels include a Web-based user interface, a back-end "ReSTlet" built in Java, and databases that store the data as it is received from the network. As part of MaROS, the innovators have developed and implemented a feature set that operates on several levels of the software architecture. This new feature is an advanced querying capability through either the Web-based user interface, or through a back-end REST interface to access all of the data gathered from the network. This software is not meant to replace the REST interface, but to augment and expand the range of available data. The current REST interface provides specific data that is used by the MaROS Web application to display and visualize the information; however, the returned information from the REST interface has typically been pre-processed to return only a subset of the entire information within the repository, particularly only the information that is of interest to the GUI (graphical user interface). The new, advanced query and data mining capabilities allow users to retrieve the raw data and/or to perform their own data processing. The query language used to access the repository is a restricted subset of the structured query language (SQL) that can be built safely from the Web user interface, or entered as freeform SQL by a user. The results are returned in a CSV (Comma Separated Values) format for easy exporting to third party tools and applications that can be used for data mining or user-defined visualization and interpretation. This is the first time that a service is capable of providing access to all cross-project relay data from a single Web resource. Because MaROS contains the data for a variety of missions from the Mars network, which span both NASA and ESA, the software also establishes an access control list (ACL) on each data record

  15. Website MA: herramienta para automatizar métricas web

    OpenAIRE

    Lafuente, Guillermo Javier; Olsina Santos, Luis Antonio

    2000-01-01

    El presente paper analiza detalles de diseño e implementación de la herramienta Website MA (Metric Automation), la cual permite automatizar algunos pasos del proceso de evaluación de la metodología Web-site QEM (Quality Evaluation Methodology). Particularmente, permite la recolección de datos automática a partir de un URL de un sitio o aplicación Web; la obtención de métricas Web, y la posterior generación de informes textuales y gráficos de las mismas. Por lo tanto, se analizará los principa...

  16. Morphology and conduction properties of graphite-filled immiscible PVDF/PPgMA blends

    OpenAIRE

    Han, Zhidong; Saracco, Guido; FINA, Alberto; Gross, U; Mainil, M.

    2012-01-01

    Graphite was dispersed in immiscible polyvinylidene "uoride/maleated polypropylene (PVDF/PPgMA) blends to improve electrical and thermal conductive properties by building a double-percolation structure. The morphology of PVDF/PPgMA blends was !rst investigated for several compositions by selective solvent extraction, scanning electron microscopy, and dynamic mechanical thermal analysis. Blends of PVDF and PPgMA were prepared in different relative fractions, and a PVDF/PPgMA ratio of 7/3 showe...

  17. 42 CFR 422.56 - Enrollment in an MA MSA plan.

    Science.gov (United States)

    2010-10-01

    ... 42 Public Health 3 2010-10-01 2010-10-01 false Enrollment in an MA MSA plan. 422.56 Section 422.56... Enrollment in an MA MSA plan. (a) General. An individual is not eligible to elect an MA MSA plan unless the... Department of Defense under 38 U.S.C. chapter 17, may not enroll in an MA MSA plan. (c) Individuals...

  18. [Herbological studies on Chinese crude drug Ma-huang. Part 1-On the botanical origin of Ma-huang in ancient China and the origin of Japanese Ma-huang].

    Science.gov (United States)

    Yoshizawa, Chieko; Kitade, Makiko; Mikage, Masayuki

    2005-01-01

    The botanical origin of a Chinese crude drug Ma-huang in ancient China and the origin of Japanese Ma-huang were herbologically studied. The results showed that the plants of Ephedra sinica Stapf, E. intermedia Schrenk & C. A. Meyer and E. equisetina Bunge were used as Ma-huang in China, and the first species was considered to be of high quality. The characters of Mao-zhou Ma-huang and Tong-zhou Ma-huang printed in Tu-jing-ben-cao, published in the Song Dynasty in China, were identified as E. likiangensis Florin and E. intermedia, respectively, and both species were recognized as excellent Ma-huang in the Ming Dynasty. The word origin of Katsune-kusa, the Japanese name for Ma-huang in the Heian Era, was etymologically considered as meaning the plant having reddish brown roots. In Japan, the plant of Equisetum ramosissimum Desf. var.japonicum Milde, of the family Equisetaceae, was substituted for Ma-huang in the middle of Edo Era, and it was designated that this action was based on the confusion of Ephedra plants and Equisetum plants those days in China.

  19. PP/Talc/MA-SEBS复合材料的力学性能研究%The Mechanical Properties of PP/Talc/MA-SEBS Composite

    Institute of Scientific and Technical Information of China (English)

    谢晓春

    2011-01-01

    PP/Talc composites compatibilized by MA-SEBS(maleic anhydride grafted styrene-(ethylene-co-butylene)-styrene copolymer) were prepared by melt extrusion, followed by injection molding. The effects of Talc and MA-SEBS on mechanical properties of PP/Talc/MA-SEBS composites were systematically investigated. The results indicated that Talc mixing into PP could obviously improve the impact strength of PP at room temperature. After the entry of MA-SEBS to the PP/Talc composites, the impact strength increased even more. MA-SEBS acted as a toughening agent as well as a compatilizer, enhancing the toughening effect of Talc. The rigid Talc particles made the flexural strength increase markedly, and the flexural moduls go up with the increase of Talc content; and elastomer MA-SEBS got the flexural performance of composites obviously deteriorated. Talc had no bad effect on the PP tensile properties; if adding Talc and MA-SEBS at the same time,the tensile strength would go down, and tend to decrease with increasing MA-SEBS content in the composites.%选用MA-SEBS为增容剂,制备了PP/滑石粉(Talc)/MA-SEBS复合材料,研究了Talc和MA-SEBS的含量对复合材料力学性能的影响.结果表明,单纯加入一定量Talc可以明显提高PP冲击强度,再加入MA-SEBs后,复合材料的冲击强度进一步增加.MA-SEBS除了作为相容剂.也充当增韧剂.刚性粒子Talc使材料的弯曲强度明显增大,弯曲模量随Talc含量增加而增大;而弹性体MA-SEBS使材料弯曲性能明显变差.单纯加入Talc对PP的拉伸性能无负面影响;若同时加入Tak和MA-SEBS,材料的拉伸强度明显下降,且MA-SEBS含量越大降幅越大.

  20. 33 CFR 165.120 - Safety Zone: Chelsea River, Boston Inner Harbor, Boston, MA.

    Science.gov (United States)

    2010-07-01

    ..., Boston Inner Harbor, Boston, MA. 165.120 Section 165.120 Navigation and Navigable Waters COAST GUARD... § 165.120 Safety Zone: Chelsea River, Boston Inner Harbor, Boston, MA. (a) Location. The following area... downstream of the Chelsea Street Bridge on the Chelsea, MA side of the Chelsea River—hereafter referred to...

  1. 42 CFR 422.618 - How an MA organization must effectuate standard reconsidered determinations or decisions.

    Science.gov (United States)

    2010-10-01

    ... 42 Public Health 3 2010-10-01 2010-10-01 false How an MA organization must effectuate standard... Grievances, Organization Determinations and Appeals § 422.618 How an MA organization must effectuate standard reconsidered determinations or decisions. (a) Reversals by the MA organization—(1) Requests for service. If,...

  2. 46 CFR 308.532 - Release of surety bond, Form MA-312.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 8 2010-10-01 2010-10-01 false Release of surety bond, Form MA-312. 308.532 Section 308.532 Shipping MARITIME ADMINISTRATION, DEPARTMENT OF TRANSPORTATION EMERGENCY OPERATIONS WAR RISK..., Form MA-312. The Standard Form of Release of Surety bond, Form MA-312, may be obtained from...

  3. 76 FR 77591 - Proposed Collection; Comment Request for Form 1099-MA

    Science.gov (United States)

    2011-12-13

    ... Internal Revenue Service Proposed Collection; Comment Request for Form 1099-MA AGENCY: Internal Revenue...(c)(2)(A)). Currently, the IRS is soliciting comments concerning Form 1098-MA, Mortgage Assistance... Assistance Payments. OMB Number: 1545-2221. Form Number: Form 1099-MA. Abstract: This form is a...

  4. 46 CFR 308.545 - Facultative cargo policy, Form MA-316.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 8 2010-10-01 2010-10-01 false Facultative cargo policy, Form MA-316. 308.545 Section 308.545 Shipping MARITIME ADMINISTRATION, DEPARTMENT OF TRANSPORTATION EMERGENCY OPERATIONS WAR RISK... policy, Form MA-316. The standard form of War Risk Facultative Cargo Policy, Form MA-316, may be...

  5. 46 CFR 308.549 - Application for appointment of Cargo Underwriting Agent, Form MA-319.

    Science.gov (United States)

    2010-10-01

    ..., Form MA-319. 308.549 Section 308.549 Shipping MARITIME ADMINISTRATION, DEPARTMENT OF TRANSPORTATION... appointment of Cargo Underwriting Agent, Form MA-319. Any domestic insurance company authorized to do a marine... by submitting to the Maritime Administrator a letter and Form MA-399, which may be obtained from...

  6. 46 CFR 308.306 - Second Seamen's War Risk Policy, Form MA-242.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 8 2010-10-01 2010-10-01 false Second Seamen's War Risk Policy, Form MA-242. 308.306... RISK INSURANCE Second Seamen's War Risk Insurance § 308.306 Second Seamen's War Risk Policy, Form MA-242. (a) The standard form of Second Seamen's War Risk Policy Form MA-242, may be obtained from...

  7. 46 CFR 308.547 - Application for return premium, Form MA-317.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 8 2010-10-01 2010-10-01 false Application for return premium, Form MA-317. 308.547... for return premium, Form MA-317. An application for the return of premium must be filed in duplicate with the Underwriting Agent on Form MA-317, which may be obtained from the American War Risk Agency...

  8. 46 CFR 308.527 - Application for return premium, Form MA-307.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 8 2010-10-01 2010-10-01 false Application for return premium, Form MA-307. 308.527... for return premium, Form MA-307. An application for the return of premium, which may be obtained from... MA-307....

  9. 46 CFR 308.517 - Open Cargo Policy, Form MA-300.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 8 2010-10-01 2010-10-01 false Open Cargo Policy, Form MA-300. 308.517 Section 308.517... Risk Cargo Insurance Ii-Open Policy War Risk Cargo Insurance § 308.517 Open Cargo Policy, Form MA-300. The standard form of War Risk Open Cargo, Form MA-300, may be obtained from the American War...

  10. 46 CFR 308.534 - Certificate to be attached to closing report, Form MA-313-A.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 8 2010-10-01 2010-10-01 false Certificate to be attached to closing report, Form MA... § 308.534 Certificate to be attached to closing report, Form MA-313-A. The standard form of Certificate to be attached to the closing report, Form MA-313-A, may be obtained from the American War...

  11. 46 CFR 308.524 - Application for cancellation of Open Cargo Policy, Form MA-304.

    Science.gov (United States)

    2010-10-01

    ... MA-304. 308.524 Section 308.524 Shipping MARITIME ADMINISTRATION, DEPARTMENT OF TRANSPORTATION... § 308.524 Application for cancellation of Open Cargo Policy, Form MA-304. The standard form of application for cancellation of an Open Cargo Policy Form MA-304 may be obtained from the American War...

  12. 42 CFR 422.553 - Effect of leasing of an MA organization's facilities.

    Science.gov (United States)

    2010-10-01

    ... 42 Public Health 3 2010-10-01 2010-10-01 false Effect of leasing of an MA organization's... Ownership or Leasing of Facilities During Term of Contract § 422.553 Effect of leasing of an MA organization's facilities. (a) General effect of leasing. If an MA organization leases all or part of...

  13. Cell cycle-dependent SUMO-1 conjugation to nuclear mitotic apparatus protein (NuMA)

    Energy Technology Data Exchange (ETDEWEB)

    Seo, Jae Sung; Kim, Ha Na; Kim, Sun-Jick; Bang, Jiyoung; Kim, Eun-A; Sung, Ki Sa [Department of Biological Sciences, Sungkyunkwan University, Suwon 440-746 (Korea, Republic of); Yoon, Hyun-Joo [TissueGene Inc. 9605 Medical Center Dr., Rockville, MD 20850 (United States); Yoo, Hae Yong [Department of Health Sciences and Technology, Samsung Advanced Institute for Health Sciences and Technology, Samsung Medical Center, Sungkyunkwan University, Seoul 135-710 (Korea, Republic of); Choi, Cheol Yong, E-mail: choicy@skku.ac.kr [Department of Biological Sciences, Sungkyunkwan University, Suwon 440-746 (Korea, Republic of)

    2014-01-03

    Highlights: •NuMA is modified by SUMO-1 in a cell cycle-dependent manner. •NuMA lysine 1766 is the primary target site for SUMOylation. •SUMOylation-deficient NuMA induces multiple spindle poles during mitosis. •SUMOylated NuMA induces microtubule bundling. -- Abstract: Covalent conjugation of proteins with small ubiquitin-like modifier 1 (SUMO-1) plays a critical role in a variety of cellular functions including cell cycle control, replication, and transcriptional regulation. Nuclear mitotic apparatus protein (NuMA) localizes to spindle poles during mitosis, and is an essential component in the formation and maintenance of mitotic spindle poles. Here we show that NuMA is a target for covalent conjugation to SUMO-1. We find that the lysine 1766 residue is the primary NuMA acceptor site for SUMO-1 conjugation. Interestingly, SUMO modification of endogenous NuMA occurs at the entry into mitosis and this modification is reversed after exiting from mitosis. Knockdown of Ubc9 or forced expression of SENP1 results in impairment of the localization of NuMA to mitotic spindle poles during mitosis. The SUMOylation-deficient NuMA mutant is defective in microtubule bundling, and multiple spindles are induced during mitosis. The mitosis-dependent dynamic SUMO-1 modification of NuMA might contribute to NuMA-mediated formation and maintenance of mitotic spindle poles during mitosis.

  14. MaROS Strategic Relay Planning and Coordination Interfaces

    Science.gov (United States)

    Allard, Daniel A.

    2010-01-01

    The Mars Relay Operations Service (MaROS) is designed to provide planning and analysis tools in support of ongoing Mars Network relay operations. Strategic relay planning requires coordination between lander and orbiter mission ground data system (GDS) teams to schedule and execute relay communications passes. MaROS centralizes this process, correlating all data relevant to relay coordination to provide a cohesive picture of the relay state. Service users interact with the system through thin-layer command line and web user interface client applications. Users provide and utilize data such as lander view periods of orbiters, Deep Space Network (DSN) antenna tracks, and reports of relay pass performance. Users upload and download relevant relay data via formally defined and documented file structures including some described in Extensible Markup Language (XML). Clients interface with the system via an http-based Representational State Transfer (ReST) pattern using Javascript Object Notation (JSON) formats. This paper will provide a general overview of the service architecture and detail the software interfaces and considerations for interface design.

  15. 5 MV 30 mA industrial electron processing system

    Science.gov (United States)

    Hoshi, Y.; Mizusawa, K.

    1991-05-01

    Industrial electron beam processing systems have been in use in various application fields such as: improving heat resistivity of wire insulation; controlling quality of automobile rubber tires and melt index characteristics of PE foams; and curing paintings or printing inks. Recently, there has come up a need for electron beam with an energy higher than 3 MV in order to disinfect salmonella in chicken meat, to kill bugs in fruits, and to sterilize medical disposables. To meet this need we developed a 5 MV 30 mA electron processing system with an X-ray conversion target. The machine was tested in NHV's plant in Kyoto at continuous operation of full voltage and full current. It proved to be very steady in operation with a high efficiency (as much as 72%). Also, the X-ray target was tested in a continuous run of 5 MV 30 mA (150 kW). It proved to be viable in industrial utilization. This paper introduces the process and the results of the development.

  16. MaROS Strategic Relay Planning and Coordination Interfaces

    Science.gov (United States)

    Allard, Daniel A.

    2010-01-01

    The Mars Relay Operations Service (MaROS) is designed to provide planning and analysis tools in support of ongoing Mars Network relay operations. Strategic relay planning requires coordination between lander and orbiter mission ground data system (GDS) teams to schedule and execute relay communications passes. MaROS centralizes this process, correlating all data relevant to relay coordination to provide a cohesive picture of the relay state. Service users interact with the system through thin-layer command line and web user interface client applications. Users provide and utilize data such as lander view periods of orbiters, Deep Space Network (DSN) antenna tracks, and reports of relay pass performance. Users upload and download relevant relay data via formally defined and documented file structures including some described in Extensible Markup Language (XML). Clients interface with the system via an http-based Representational State Transfer (ReST) pattern using Javascript Object Notation (JSON) formats. This paper will provide a general overview of the service architecture and detail the software interfaces and considerations for interface design.

  17. Welche Ausbildungsinhalte brauchen Studierende im Praktischen Jahr - Bedarfsanalyse als Basis für ein chirurgisches PJ-Curriculum [What educational content do medical students want in ther final clinical year - needs assessment as the basis for a final-year surgery curriculum

    Directory of Open Access Journals (Sweden)

    Kadmon, Martina

    2008-08-01

    Full Text Available [english] Background: The final clinical year of undergraduate medical training in Germany aims at providing more practical experience. However, most hospitals lack a structured curriculum. The Department of General Surgery at Heidelberg University, therefore, developed a systematic curriculum for this training period. Methods: In designing the new curriculum, we followed Kern’s six-step approach to curriculum development . To assess needs, students, physicians, and nurses were asked in semi-structured interviews to give their views on existing as well as desirable educational contents. Results: The interview data showed that most tasks of final-year students were fulfilled without supervision. Even skills considered very important by professionals were not audited. The accomplishment of core competencies was thus accidental. On the basis of the interview data, learning objectives were formulated and translated into adequate teaching strategies. Conclusion: The present work shows the results of our needs assessment and may serve as a model for surgery departments of any teaching hospital in Germany. [german] Hintergrund: Das Praktische Jahr (PJ soll die Umsetzung theoretischer Kenntnisse in die Praxis ermöglichen. Den meisten Ausbildungskliniken fehlt ein strukturiertes PJ-Curriculum. An der Chirurgischen Universitätsklinik Heidelberg wurde deshalb ein systematisches Curriculum für diesen Studienabschnitt entwickelt. Methoden: Die Curriculumsentwicklung folgte dem sechsstufigen Modell nach Kern . Grundlage war eine Bedarfsanalyse anhand halbstrukturierter Interviews mit Pflegepersonal, Ärzten und Studierenden, in denen deren Meinung zum existierenden Ausbildungsprogramm und zu wünschenswerten Verbesserungen abgefragt wurde. Ergebnisse: Die Analyse der Ergebnisse ergab, dass die Ausbildung nicht ausreichend auf den Arztberuf vorbereitet. Die meisten Fertigkeiten wurden durch Studierende ohne jegliche Supervision durchgeführt, der Erwerb

  18. Construction of a high modulus asphalt (HiMA) trial section Ethekwini: South Africa's first practical experience with design, manufacturing and paving of HiMA

    CSIR Research Space (South Africa)

    Nkgapele, M

    2012-07-01

    Full Text Available A trial section was paved with the recently introduced High Modulus Asphalt (HiMA) technology on South Coast road in eThekwini (Durban). The trial section forms part of an effort to transfer HiMA technology to South Africa, in an initiative aimed...

  19. Global Paleobathymetry for the Cenomanian-Turonian (90 Ma)

    Science.gov (United States)

    Goswami, A.; Olson, P.; Hinnov, L. A.; Gnanadesikan, A.

    2014-12-01

    We present a paleo-ocean bathymetry reconstruction for Cenomanian-Turonian (90 Ma) time in a 0.1°x0.1° resolution for use in paleo-climate studies. Age of the ocean floor for the Cenomanian-Turonian (90 Ma) is from Müller et al. (2008 a,b); coastlines are from the PALEOMAP Project (Scotese, 2011). To reconstruct paleo-ocean bathymetry, we use a plate model equation to model depth to basement (Turcotte and Schubert, 2002). We estimate plate model equation parameter values from measurements of modern oceans (Crosby et al., 2006). On top of the depth to basement, we isostatically add a multilayer sediment model derived from area-corrected sediment thickness data (Divins, 2003; Whittaker et al., 2013). Lastly, we parameterize the modern continental shelf, slope, and rise in a "sediment wedge model" to connect the coastline with the closest ocean crust as defined by Müller et al. (2008 a, b). These parameters are defined using empirical relationships obtained from study of modern ocean transects where a complete rifting history is preserved (Atlantic and Southern oceans), and the closest approach of the respective oceanic crust (Müller et al., 2008a,b) to the coastline. We use the modern ocean as a test, comparing maps and cross sections of modern ocean bathymetry modeled using our reconstruction method with that of ETOPO1 (Amante and Eakins, 2009). Adding sea plateaus and seamounts minimize the difference between our modeled bathymetry and ETOPO1. Finally, we also present a comparison of our reconstructed paleo-bathymetry to that of Müller et al. (2008 a,b) for the Cenomanian-Turonian (90 Ma). References: Amante, C., Eakins, B.W., 2009, NOAA Tech. Memo. NESDIS NGDC-24, 19 p. Crosby, A., McKenzie, D., Sclater, J.G., 2006, Geophysical Journal Int. 166.2, 553-573. Divins, D., 2003, NOAA NGDC, Boulder, CO. Müller, R., Sdrolias, M., Gaina, C., Roest, W., 2008b, Geochemistry, Geophysics, Geosystems, 9, Q04006, doi:10.1029/2007GC001743 Müller, R., Sdrolias, M., Gaina

  20. SCHeMA open and modular in situ sensing solution

    Science.gov (United States)

    Tercier-Waeber, Marie Louise; Novellino, Antonio

    2017-04-01

    Marine environments are highly vulnerable and influenced by a wide diversity of anthropogenic and natural substances and organisms that may have adverse effects on the ecosystem equilibrium, on living resources and, ultimately, on human health. Identification of relevant types of hazards at the appropriate temporal and spatial scale is crucial to detect their sources and origin, to understand the processes governing their magnitude and distribution, and to ultimately evaluate and manage their risks and consequences preventing economic losses. This can be addressed only by the development of innovative, compact, rugged, automated, sensor networks allowing long-term monitoring. Development of such tools is a challenging task as it requires many analytical and technical innovations. The FP7-OCEAN 2013-SCHeMA project aims to contribute to meet this challenge by providing an open and modular sensing solution for autonomous in situ high resolution mapping of a range of anthropogenic and natural chemical compounds (trace metals, nutrients, anthropogenic organic compounds, toxic algae species and toxins, species relevant to the carbon cycle). To achieve this, SCHeMA activities focus on the development of : 1) an array of miniature sensor probes taking advantage of various innovative solutions, namely: (polymer-based) gel-integrated sensors; solid state ion-selective membrane sensors coupled to an on-line desalination module; mid-infrared optical sensors; optochemical multichannel devices; enOcean technology; 2) dedicated hardware, firmware and software components allowing their plug-and-play integration, localization as well as wireless bidirectional communication via advanced OGC-SWE wired/wireless dedicated interfaces; 3) a web-based front-end system compatible with EU standard requirements and principles (INSPIRE, GEO/GEOSS) and configured to insure easy interoperability with national, regional and local marine observation systems. This lecture will present examples of

  1. MaRV (maneuverable reentry vehicles) PoP (probability of penetration) vs CEP (circular error probability) analysis concept study (MaRV Penetration Study Project)

    Energy Technology Data Exchange (ETDEWEB)

    Morris, J M

    1986-08-01

    The performance analysis of maneuverable reentry vehicles (MaRV) in terms of its probability of penetration (PoP) against terminal engagement with a ballistic missile defense (BMD) system and in terms of its associate circular error probability (CEP), at impact is a very complex problem. A thorough study of this problem under the MaRV Penetration Study Project will require the development of a number of analytical and simulation tools. As a result of a preliminary study, a MaRV PoP vs CEP analysis concept has been formulated to support the MaRV Penetration Study Project. The concept is based on analytical models and techniques and, moreover, exploits the existing knowledge base and is physically intuitive. The analysis concept, as formulated, is applicable to arbitrary MaRV's and BMD systems.

  2. Teresa Uzeda e i suoi Maîtres

    Directory of Open Access Journals (Sweden)

    Rosalba Galvagno

    2013-12-01

    Full Text Available La biografia diTeresa Uzeda narrata da Federico De Roberto nell’Illusione (1891, il primo grande romanzo del ciclo degli Uzedainsieme a I Viceré (1894 e a L’imperio (1929, comprende anche l’istruzionedella giovane eroina, che comincia a studiare dapprima - ha 10 anni all’iniziodel romanzo - sotto la direzione di Miss, per essere poi seguita da altriprofessori di lettere, di storia, di disegno, di canto, fino all’età di 17 annicirca. Ma, accanto all’istruzione ‘scolastica’, Teresa avrà accesso, graziealla sua devotissima serva Stefana, all’universo incantato e perturbante dellefiabe, e quindi, spinta dalla sua trasgressiva curiositas, all’universo altrettanto incantato e periglioso deiromanzi e del teatro, il melodramma innanzitutto.Quale Bildung si prefigura allora per ildestino di Teresa, questa infelice, incompresa e originalissima Bovarysiciliana?

  3. Isolated Galaxies versus Interacting Pairs with MaNGA

    CERN Document Server

    Argudo-Fernández, M; Shen, S; Yin, J; Chang, R; Feng, S

    2015-01-01

    We present preliminary results of the spectral analysis on the radial distributions of the star formation history in both, a galaxy merger and a spiral isolated galaxy observed with MaNGA. We find that the central part of the isolated galaxy is composed by older stellar population ($\\sim$2 Gyr) than in the outskirts ($\\sim$7 Gyr). Also, the time-scale is gradually larger from 1 Gyr in the inner part to 3 Gyr in the outer regions of the galaxy. In the case of the merger, the stellar population in the central region is older than in the tails, presenting a longer time-scale in comparison to central part in the isolated galaxy. Our results are in agreement with a scenario where spiral galaxies are built from inside-out. In the case of the merger, we find evidence that interactions enhance star formation in the central part of the galaxy.

  4. maíz con Datura stramonium en ganado vacuno

    Directory of Open Access Journals (Sweden)

    FX Bofill

    2007-01-01

    Full Text Available Recientemente hemos observado dos intoxicaciones en ganado vacuno lechero, en granjas de Cataluña, debidas a la ingestión de estramonio (Datura stramonium. La planta había sido en ambos casos erróneamente recolectada junto con el maíz empleado para la alimentación de los animales. El cuadro fue leve y, básicamente, cursó con problemas digestivos y descenso en la producción lechera, y remitió con la retirada del alimento contaminado. Debido a factores ambientales y económicos, el problema podría estar en aumento.

  5. Interfacing transformer for a pulsed load current exceeding 1 MA

    CERN Document Server

    Cliffe, R J; Brown, J

    2003-01-01

    In much pulsed power experimentation a capacitor bank is discharged into an inductive load, but although sufficient energy may be available in the capacitors their voltage rating may considerably exceed that necessary for the load and the current delivered during the experiment may accordingly be too low. This paper describes a novel design of air-cored transformer that has been used as an interfacing or matching device in such a situation, where peak load currents between 1 and 2 MA were required. Design considerations led to the use of an air-cored autotransformer connection wound with copper sheet conductors. Although thick wide conductors and clamping are needed to prevent deformation due to high magnetic pressure, the transformer is nevertheless relatively simple, easy to make, lightweight and inexpensive. This paper describes the design and the winding arrangement of the transformer that was constructed, and presents typical experimental results.

  6. Le Maître des aveux, Thierry Cruvellier

    OpenAIRE

    Luc Benaiche

    2013-01-01

    Le livre de Thierry Cruvellier porte sur le procès de Duch, le directeur de la prison S-21 où périrent environ 14 000 détenus sous le régime khmer rouge (1975-1979). Le titre est à double sens : Duch était celui qui présidait à l’obtention des aveux des détenus avant leur « écrasement », c’est-à-dire leur exécution, mais il est également celui qui fait ses propres aveux au travers de ce tribunal, tout en en restant « maître », dans la mesure du possible. L’ossature de l’ouvrage – 360 pages dé...

  7. Le Maître des aveux, Thierry Cruvellier

    Directory of Open Access Journals (Sweden)

    Luc Benaiche

    2012-10-01

    Full Text Available Le livre de Thierry Cruvellier porte sur le procès de Duch, le directeur de la prison S-21 où périrent environ 14 000 détenus sous le régime khmer rouge (1975-1979. Le titre est à double sens : Duch était celui qui présidait à l’obtention des aveux des détenus avant leur « écrasement », c’est-à-dire leur exécution, mais il est également celui qui fait ses propres aveux au travers de ce tribunal, tout en en restant « maître », dans la mesure du possible. L’ossature de l’ouvrage – 360 pages dé...

  8. Isolated Galaxies versus Interacting Pairs with MaNGA

    Science.gov (United States)

    Fernández, María; Yuan, Fangting; Shen, Shiyin; Yin, Jun; Chang, Ruixiang; Feng, Shuai

    2015-10-01

    We present preliminary results of the spectral analysis on the radial distributions of the star formation history in both, a galaxy merger and a spiral isolated galaxy observed with MaNGA. We find that the central part of the isolated galaxy is composed by older stellar population ($\\sim$2 Gyr) than in the outskirts ($\\sim$7 Gyr). Also, the time-scale is gradually larger from 1 Gyr in the inner part to 3 Gyr in the outer regions of the galaxy. In the case of the merger, the stellar population in the central region is older than in the tails, presenting a longer time-scale in comparison to central part in the isolated galaxy. Our results are in agreement with a scenario where spiral galaxies are built from inside-out. In the case of the merger, we find evidence that interactions enhance star formation in the central part of the galaxy.

  9. Ein Universum nach Maß. Bedingungen unserer Existenz.

    Science.gov (United States)

    Gribbin, J.; Rees, M.

    This book is a German translation, by A. Ehlers, of the English original "Cosmic coincidences. Dark matter, mankind, and anthropic cosmology", published in 1989 (see 52.003.043). Contents: I. Zufälle im Weltall. 1. Wie außergewöhnlich ist unsere Welt? 2. Himmelskunde. 3. Zwei Arten dunkler Materie. II. Der Stoff aus dem die Welt besteht. 4. Der Teilchenzoo. 5. Halomaterie. 6. Der Stoff, aus dem die Kerne sind. 7. Kosmische Strings. 8. Die Schwerkraft als Fernrohr. 9. Der Lyman-Wald: Entstehung und Entwickluing von Galaxien. III. Ein Universum nach Maß? 10. Dem Menschen auf den Leib geschneidert? 11. Ein Weltall von der Stange?

  10. de labranza en el cultivo de maíz

    Directory of Open Access Journals (Sweden)

    Pedro Paneque Rondón

    2005-01-01

    Full Text Available Como parte de las investigaciones que se llevan a cabo en la Universidad Agraria de La Habana (UNAH, en el Centro de Mecanización Agropecuaria (CEMA, dirigidas al desarrollo de la Agricultura de Conservación, el objetivo del presente trabajo fue determinar el costo energético de las principales operaciones agrícolas mecanizadas en tres sistemas de preparación de suelo, cuantificar su posible ahorro utilizando los sistemas de labranza conservacionistas, en relación con el sistema convencional, partiendo de la hipótesis de que es posible economizar energía usando dichos sistemas. El trabajo fue desarrollado en las áreas docentes de la Universidad Agraria de La Habana (UNAH, La Habana, Cuba, donde está localizado el polígono de la Facultad de Agronomía, fueron utilizados diseños experimentales en bloques al azar para determinar el costo energético y los indicadores agrotécnicos del cultivo del maíz a diferentes profundidades de preparación de suelo. Los resultados de la investigación permitieron llegar a las siguientes conclusiones: la labranza cero tiene un costo energético de sólo 48,29 % del costo del sistema convencional y la labranza reducida alcanza 77,18 %, siendo posible ahorrar entre 2 326,81 y 1 026,67 MJ•ha-1 equivalentes a 48,68 y 21,48 litros de combustible diesel por cada hectárea trabajada. Los otros resultados de la investigación no indican diferencias significativas en los tratamientos a distintas profundidades de preparación del suelo, por lo que es favorable sembrar el maíz a menos de 10 cm de profundidad

  11. MaTeLo: Automated Testing Suite for Software Validation

    Science.gov (United States)

    Guiotto, A.; Acquaroli, B.; Martelli, A.

    It is universally known that testing has a predominant role when developing software: more and more efforts are spent on testing to detect programming faults, to evaluate the code reliability or performance, to ensure that a critical function of a system meets given requirements. The ratio of time spent on testing should not be neglected and this explains why there is a real need to improve the development process, especially as systems are becoming larger and larger. It is necessary to keep under control the schedule and budget of developments, and controlling the testing phase is a real issue, often underestimated in many industrial sectors. The industry is heightened at different stages regarding testing, and the MaTeLo project is committed to promote the use of statistical tools &methods to answer European industry's needs: • have the ability to choose relevant test cases instead of a human- biased selection • know when to stop testing (definition of a stopping criteria) instead of a vague and informal criteria • adopt an identical strategy for different developments • automate the testing process, and thus to make testing not human error prone MaTeLo (Markov Test Logic) study is a study currently under development in the frame of the IST program of the European Community. The aim of the project is to define, implement and validate a new approach for supporting the software testing activities in various industrial fields. One of the major goals is in particular to provide the software teams with a new tool able to automatically produce and execute the Test Cases starting from the software specifications. Further, the tool is conceived to provide metrics that could help technical staff to determine software quality and to evaluate how much expected results are met. The tool is based on Markov chains theory and belongs to statistical testing software tools family [Runeson] [Whittaker].

  12. Ma ma (2015: un reflejo de la mujer española con cáncer de mama

    Directory of Open Access Journals (Sweden)

    Clara Peralta?Nueno et al.

    2017-03-01

    Full Text Available Ma ma (2015 es una película de drama española dirigida por Julio Medem y producida por Morena Films. Esta película narra la historia de la vida de Magda cuyo personaje es interpretado por Penélope Cruz. Tras serle diagnosticado un cáncer de mama, Magda, una maestra en paro, no sabrá cómo actuar ni de qué manera cambiará esta enfermedad su vida, pero poco a poco sacará a la superficie toda su energía vital. El cáncer de mama representa el tipo de cáncer más frecuente en la mujer. Aunque la mayoría de los factores de riesgo identificados pueden ser modificables, los sistemas de salud se concentran en actividades que permiten fortalecer la prevención primaria y actividades de prevención secundaria y terciaria. La detección temprana y el tratamiento adecuado son indispensables para luchar contra esta enfermedad. El proceso emocional generado por la presencia de cáncer, conlleva un mecanismo de reconstitución psíquico que permite a la paciente conformar una respuesta a los desafíos orgánicos, cognitivos, sociales y emocionales a los cuales se ve enfrentada. Dicho proceso es favorecido entre otros factores por contar con una red de apoyo socio?familiar sólida.

  13. MA Transmutation Strategy%MA嬗变策略研究

    Institute of Scientific and Technical Information of China (English)

    左国平; 柯国土; 龚学余

    2011-01-01

    According to the development plan envisagement for nuclear power plant in China, the development of China's nuclear power in the next decades is predicted with the. nuclear fuel cycle software NFCSS provided by IAEA. The amounts of the spent fuel generated and accumulated by the year of 2050 are analyzed. According to the assumption model, the accumulated spent fuel by the year of 2050 will reach at 54791t including 57.89t Minor Actinides (MA) (237Np, 42.91t; Am, ll.17t; Cm, 3.81t) and 2778t FP. One group effective cross section of MA in the thermal, well thermalized, and fast neutron field is calculated based on ENDF/B-VII nuclear evaluation database. The transmutation way for three main MA, i.e. 237Np, 241Am, and 246Cm is also analyzed. It is more suitable for 237Np transmutation in well thermalized neutron field and for 241Am, the high flux thermalized neutron field is better. But it is difficult for 246Cm transmutation in thermal or fast neutron field due to its little fission cross section. Its transmutation ability can be improved if transmutation occurs in a high fluxes resonance energy area. The two-stage transmutation strategy is presented according to their characteristics in the thermal, well thermalized, and fast neutron field. Based on the two stage transmutation concept, the transmutation is performed in a well thermalized neutron field first. Small amount of residual of the first stage transmutation is transmuted in a thermal field with a spectrum. It is expected to achieve a good result.%根据中国核电发展战略,采用国际原子能机构(IAEA)的核燃料循环软件NFCSS,对未来中国核电发展情景进行了预测,分析了2050年以前中国乏燃料的产生和累积情况.采用NJOY和ENDF/B-VII数据库,计算分析了次锕系核素在热谱、超热谱和快谱中的一群等效截面,分析了研237Np、241Am、246Cm等主要次锕系核素的可能嬗变途径,提出了两阶段嬗变MA策略.即将从压水堆中分离出来

  14. Defoliación en maíz y su efecto sobre el rendimiento de frijol-maíz en asociación

    OpenAIRE

    Rafael Delgado Martínez; José Alberto Salvador Escalante Estrada; Ramón Díaz Ruíz; Antonio Trinidad Santos; Edgar Jesús Morales Rosales; Eliseo Sosa Montes

    2014-01-01

    El rendimiento tanto de maíz y frijol en monocultivo está determinado por el genotipo y el ambiente. Sin embargo, la siembra asociada de estos cultivos puede incrementar la producción por unidad de área. No obstante, el efecto de competencia interespecifica donde el frijol es más afectado y que se asume al sombreado del maíz sobre el frijol ha sido poco atendido. El objetivo del estudio fue determinar el efecto de la defoliación del maíz sobre la biomasa total (BT), índice de cosecha ...

  15. Development of a Hydronic Rooftop Unit-HyPak-MA

    Energy Technology Data Exchange (ETDEWEB)

    Lee, Eric; Berman, Mark

    2009-11-14

    The majority of U.S. commercial floor space is cooled by rooftop HVAC units (RTUs). RTU popularity derives chiefly from their low initial cost and relative ease of service access without disturbing building occupants. Unfortunately, current RTUs are inherently inefficient due to a combination of characteristics that unnecessarily increase cooling loads and energy use. 36% percent of annual U.S. energy, and two-thirds of electricity, is consumed in and by buildings. Commercial buildings consume approximately 4.2 quads of energy each year at a cost of $230 billion per year, with HVAC equipment consuming 1.2 quads of electricity. More than half of all U.S. commercial floor space is cooled by packaged HVAC units, most of which are rooftop units (RTUs). Inefficient RTUs create an estimated 3.5% of U.S. CO{sub 2} emissions, thus contributing significantly to global warming5. Also, RTUs often fail to maintain adequate ventilation air and air filtration, reducing indoor air quality. This is the second HyPak project to be supported by DOE through NETL. The prior project, referred to as HyPak-1 in this report, had two rounds of prototype fabrication and testing as well as computer modeling and market research. The HyPak-1 prototypes demonstrated the high performance capabilities of the HyPak concept, but made it clear that further development was required to reduce heat exchanger cost and improve system reliability before HyPak commercialization can commence. The HyPak-1 prototypes were limited to about 25% ventilation air fraction, limiting performance and marketability. The current project is intended to develop a 'mixed-air' product that is capable of full 0-100% modulation in ventilation air fraction, hence it was referred to as HyPak-MA in the proposal. (For simplicity, the -MA has been dropped when referencing the current project.) The objective of the HyPak Project is to design, develop and test a hydronic RTU that provides a quantum improvement over

  16. Efficiency drawbacks within complex M&A integrations : - A study that observes leadership affection

    OpenAIRE

    Mikiver, Helene; Persson, Ida

    2013-01-01

    There is a recurring interest and attention regarding the problems with M&A integrations andthe difficulty to implement these successfully. Focus is often set on necessary financialaspects and smart strategic moves but equally important factors such as leadership andculture has recently been shown to be crucial. The purpose of this study has been to identify potential kinds of efficiency drawbacks inchange management situations of complex M&A integrations. Complex M&A integrations...

  17. 46 CFR 308.528 - Surety Bond A, Form MA-308.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 8 2010-10-01 2010-10-01 false Surety Bond A, Form MA-308. 308.528 Section 308.528... Risk Cargo Insurance Ii-Open Policy War Risk Cargo Insurance § 308.528 Surety Bond A, Form MA-308. The Standard Form of Surety Bond A, Form MA-308, which may be obtained from the American War Risk Agency...

  18. REGENERASI DAN PERBANYAKAN RUMPUT LAUT Kappaphycus alvarezii HASIL TRANSFORMASI GEN SUPEROKSIDA DISMUTASE (MaSOD)

    OpenAIRE

    Emma Suryati; Hidayah Triana; Utut Widiastuti; Andi Tenriulo

    2017-01-01

    Transformasi gen superoxide dismutase (MaSOD) pada rumput laut Kappaphycus alvarezii menggunakan Agrobacterium tumefacient telah dilakukan secara in vitro. Transformasi gen MaSOD ke dalam genom rumput laut diharapkan dapat mengurangi cekaman oksidatif terutama yang disebabkan oleh perubahan suhu, salinitas, dan cemaran logam di perairan. Penelitian ini bertujuan untuk regenerasi rumput laut hasil introduksi gen MaSOD dan non-transgenik pada labu kultur. Regenerasi dan perbanyakan rumput laut ...

  19. M&A and restructuring in China’s capital markets:characteristics and policies

    Institute of Scientific and Technical Information of China (English)

    张文魁

    2009-01-01

    In recent years,M&A and restructuring have gained traction in China’s capital markets.In the midst of intensifying capitalization, M&A and restructuring have been closely intertwined with capital markets.This paper attempts to identify and analyze M&A patterns, issues and policy implications based on a thorough examination of M&A and restructuring practices in China’s capital markets.

  20. Proposal MaMBA - Moon and Mars Base Analog

    Science.gov (United States)

    Heinicke, Christiane; Foing, Bernard

    2017-04-01

    Despite impressive progress in robotic exploration of celestial bodies, robots are believed to never reach the effectiveness and efficiency of a trained human. Consequently, ESA proposes to build an international Moon Village in roughly 15 years and NASA plans for the first manned mission to Mars shortly after. One of the challenges still remaining is the need for a shelter, a habitat which allows human spacefarers to safely live and work on the surface of a celestial body. Although various prototype habitats have been built and inhabited during the last decade, they typically share two fundamental flaws: First, they usually consist of a single space, which may become uninhabitable after depressurization due to just one single catastrophic event. Second, none of the habitats provides shielding against radiation, one of the major health concerns for spacefaring crews. Project MaMBA will address these two problems at the root and build an underground habitat comprised of five connected, but independent modules. The habitat will serve for testing technologies like life support, power systems, and interplanetary communication. Special attention will be given to the development of the geoscience laboratory module. In addition to the technological aspects, the envisioned habitat will serve as a unique test ground for studies on the effects of underground habitation on a crew.

  1. Molecular Mechanism of Isocupressic Acid Supresses MA-10 Cell Steroidogenesis

    Directory of Open Access Journals (Sweden)

    Kuan-Hao Tsui

    2012-01-01

    Full Text Available Consumption of ponderosa pine needles causes late-term abortions in cattle and is a serious poisonous plant problem in foothill and mountain rangelands. Isocupressic acid (IA is the component of pine needles responsible for the abortifacient effect, its abortifacient effect may be due to inhibition of steroidogenesis. To investigate the more detail molecular mechanism, we used MA-10 cell, which is wild used to investigate molecular mechanism of steroidogenesis, to characterize the molecular mechanisms underlying the actions of IA in more detail. In this report, we focus on the function of IA on important steroidogenic genes, including steroidogenic acute regulatory protein (StAR, cytochrome P450 cholesterol side-chain cleavage (P450scc, and 3β-hydroxysteroid dehydrogenase (3β-HSD. We found that IA does not affect enzyme activities of these genes but inhibits transcription of P450scc and translation of StAR and P450scc through attenuating cAMP-PKA signaling. Thus, steroid productions of cells were suppressed.

  2. SDSS-IV/MaNGA: Spectrophotometric Calibration Technique

    CERN Document Server

    Yan, Renbin; Bershady, Matthew A; Law, David R; Schlegel, David J; Bundy, Kevin; Drory, Niv; MacDonald, Nicholas; Bizyaev, Dmitry; Blanc, Guillermo A; Blanton, Michael R; Cherinka, Brian; Eigenbrot, Arthur; Gunn, James E; Harding, Paul; Hogg, David W; Sánchez-Gallego, José R; Sánchez, Sebastian F; Wake, David A; Weijmans, Anne-Marie; Xiao, Ting; Zhang, Kai

    2015-01-01

    Mapping Nearby Galaxies at Apache Point Observatory (MaNGA), one of three core programs in the Sloan Digital Sky Survey-IV (SDSS-IV), is an integral-field spectroscopic (IFS) survey of roughly 10,000 nearby galaxies. It employs dithered observations using 17 hexagonal bundles of 2 arcsec fibers to obtain resolved spectroscopy over a wide wavelength range of 3,600-10,300A. To map the internal variations within each galaxy, we need to perform accurate {\\it spectral surface photometry}, which is to calibrate the specific intensity at every spatial location sampled by each individual aperture element of the integral field unit. The calibration must correct only for the flux loss due to atmospheric throughput and the instrument response, but not for losses due to the finite geometry of the fiber aperture. This requires the use of standard star measurements to strictly separate these two flux loss factors (throughput versus geometry), a difficult challenge with standard single-fiber spectroscopy techniques due to v...

  3. Personal Hygiene Practices among Urban Homeless Persons in Boston, MA.

    Science.gov (United States)

    Leibler, Jessica H; Nguyen, Daniel D; León, Casey; Gaeta, Jessie M; Perez, Debora

    2017-08-18

    Persons experiencing homelessness in the United States experience significant barriers to self-care and personal hygiene, including limited access to clean showers, laundry and hand washing facilities. While the obstacles to personal hygiene associated with homelessness may increase risk of infectious disease, hygiene-related behaviors among people experiencing homelessness has received limited attention. We conducted a cross-sectional study of individuals experiencing homelessness in Boston, MA (n = 194) to identify hygiene-related self-care practices and risk factors for reduced hygiene in this population. Most participants (72%) reported taking a daily shower. More than 60% reported hand washing with soap five or more times each day, and use of hand sanitizer was widespread (89% reported using sanitizer in the last week). A majority (86%) used a laundromat or laundry machine to wash clothing, while 14% reported washing clothing in the sink. Heavy drinking, injection drug use, and sleeping outdoors were identified as significant risk factors for reduced hygiene practices. People experiencing homelessness who also engage in these activities may be among the most difficult to reach for intervention, yet targeted efforts may decrease illness risk associated with reduced hygiene. Housed friends and family play a critical role in assisting homeless individuals maintain hygiene by providing showers and laundry facilities.

  4. El ayer, el hoy y el mañana

    Directory of Open Access Journals (Sweden)

    Corredor Pardo Katya Anyud

    1999-12-01

    Full Text Available

    Culturalmente, el anciano de hoy en nuestra sociedad, o en las grandes urbes, es considerado algunas veces por los jóvenes como un ser extraño y desagradable, como punto de partida de los  valores transmitidos en la familia los cuales deben ser revaluados y nosotros, los ancianos del mañana con los ancianos de hoy, cambiar de adentro hacia fuera. A su vez, evitar la transmisión generacional de estos valores a nuestros hijos realizando un análisis retrospectivo de la vida; cuando bebes, se tiene conciencia del uno al otro, y los niños en edad preescolar empiezan a conseguir compañeros, pero el grupo de amigos se fortalece a partir de los cinco o siete años, con frecuencia se escucha hablar con nostalgia de la vida en el colegio. Este lugar común es grato y feliz, adornado con carcajadas y anécdotas que despiertan e incentivan la imaginación y la realidad creada a partir del propio yo social, individual y cultural.

  5. Hanford External Dosimetry Technical Basis Manual PNL-MA-842

    Energy Technology Data Exchange (ETDEWEB)

    Rathbone, Bruce A.

    2005-02-25

    The Hanford External Dosimetry Technical Basis Manual PNL-MA-842 documents the design and implementation of the external dosimetry system used at Hanford. The manual describes the dosimeter design, processing protocols, dose calculation methodology, radiation fields encountered, dosimeter response characteristics, limitations of dosimeter design under field conditions, and makes recommendations for effective use of the dosimeters in the field. The manual describes the technical basis for the dosimetry system in a manner intended to help ensure defensibility of the dose of record at Hanford and to demonstrate compliance with 10 CFR 835, DOELAP, DOE-RL, ORP, PNSO, and Hanford contractor requirements. The dosimetry system is operated by PNNL’s Hanford External Dosimetry Program which provides dosimetry services to all Hanford contractors. The primary users of this manual are DOE and DOE contractors at Hanford using the dosimetry services of PNNL. Development and maintenance of this manual is funded directly by DOE and DOE contractors. Its contents have been reviewed and approved by DOE and DOE contractors at Hanford through the Hanford Personnel Dosimetry Advisory Committee which is chartered and chaired by DOE-RL and serves as means of coordinating dosimetry practices across contractors at Hanford. This manual was established in 1996. Since inception, it has been revised many times and maintained by PNNL as a controlled document with controlled distribution. Rev. 0 marks the first revision to be released through PNNL’s Electronic Records & Information Capture Architecture (ERICA) database.

  6. Mujer, trabajo y persistencia del maíz

    Directory of Open Access Journals (Sweden)

    Erika Román Montes de Oca

    2013-01-01

    Full Text Available El presente artículo se elaboró con la intención de destacar el lugar que ocupan las mujeres en la sociedad de Amatlán de Quetzalcóatl, tomando para ello como punto principal el trabajo que realizan y el papel que cumplen en la unidad familiar al incidir en la permanencia del maíz en la comunidad y en la trasmisión de los valores para dicha persistencia. Se encontró que a pesar de prevalecer una familia con estructura patriarcal en el seno familiar, la mujer ocupa un lugar de respeto y unión, aportando opiniones y decisiones que son valoradas. También se vislumbran factores de cambio en la comunidad y en la actividad de las mujeres hacia ámbitos extra domésticos. Para este trabajo se realizaron 95 encuestas a nivel de la unidad familiar y diez entrevistas a profundidad.

  7. Voix over et peur au cinéma

    Directory of Open Access Journals (Sweden)

    Martin Barnier

    2012-07-01

    Full Text Available Les voix over de narration peuvent servir à effrayer les spectateurs de cinéma. Depuis les bonimenteurs-conférenciers des salles d’avant 1914, jusqu’aux films d’horreur des années 1970, en passant par les films des années 1930 et 1940, les voix placées sur des images peuvent créer une atmosphère lugubre. Le contraste entre une voix susurrée et des images pleines de suspens, est générateur d’angoisse. Des exemples tirés de films de Lang, Hitchcock, Tourneur, ou de cinéastes bien moins connus, permettent de vérifier que les voix over s’intègrent dans une longue tradition mais qu’elles évoluent constamment.Voice over can be use to frighten movie audiences. From the film lecturer before 1914 to the 1970s Horror movies, voices accompanying images can create a gloomy atmosphere. Contrast between suspenseful images and a whispering voice can generate fear. With examples taken from Lang, Hitchcock, Tourneur, and unknown directors, we will show that voice over creates fear since a long tradition. But each time it evolves in a different way.

  8. Cell cycle-regulated membrane binding of NuMA contributes to efficient anaphase chromosome separation.

    Science.gov (United States)

    Zheng, Zhen; Wan, Qingwen; Meixiong, Gerry; Du, Quansheng

    2014-03-01

    Accurate and efficient separation of sister chromatids during anaphase is critical for faithful cell division. It has been proposed that cortical dynein-generated pulling forces on astral microtubules contribute to anaphase spindle elongation and chromosome separation. In mammalian cells, however, definitive evidence for the involvement of cortical dynein in chromosome separation is missing. It is believed that dynein is recruited and anchored at the cell cortex during mitosis by the α subunit of heterotrimeric G protein (Gα)/mammalian homologue of Drosophila Partner of Inscuteable/nuclear mitotic apparatus (NuMA) ternary complex. Here we uncover a Gα/LGN-independent lipid- and membrane-binding domain at the C-terminus of NuMA. We show that the membrane binding of NuMA is cell cycle regulated-it is inhibited during prophase and metaphase by cyclin-dependent kinase 1 (CDK1)-mediated phosphorylation and only occurs after anaphase onset when CDK1 activity is down-regulated. Further studies indicate that cell cycle-regulated membrane association of NuMA underlies anaphase-specific enhancement of cortical NuMA and dynein. By replacing endogenous NuMA with membrane-binding-deficient NuMA, we can specifically reduce the cortical accumulation of NuMA and dynein during anaphase and demonstrate that cortical NuMA and dynein contribute to efficient chromosome separation in mammalian cells.

  9. Development of a dispersion strengthened copper alloy using a MA-HIP method

    Directory of Open Access Journals (Sweden)

    T. Yamada

    2016-12-01

    Full Text Available A new Cu-Al alloy was fabricated by a MA-HIP method for application to the heat sink materials of divertors. With the increase in MA time, the grain size and Vickers hardness decreased and increased, respectively. At MA time of 32hrs, the hardness of the alloy was comparable to that of Glidcop® although the grain size was much larger. X-ray diffractometry, electrical resistivity measurements and STEM-EDS analyses suggested precipitation of Al-rich phase by MA for 32hrs followed by HIP.

  10. SDSS-IV MaNGA: Data Products, Quality, and Initial Public Release

    Science.gov (United States)

    Law, David R.; Cherinka, Brian; MaNGA Team

    2016-01-01

    As a spectroscopic imaging survey, MaNGA presents a host of technical challenges ranging from spectrophotometic calibration to image reconstruction. I will present an overview of the MaNGA data reduction pipeline (DRP) and the algorithms used to process the MaNGA data. Additionally, I will describe the format and quality of the MaNGA data products, and the means by which the first year of survey data will be made publicly available in SDSS Data Release 13 (DR-13).

  11. 关于Ma(n)é集与Aubry集的研究%On Ma(n)é Set and Aubry Set

    Institute of Scientific and Technical Information of China (English)

    梁雪; 陈翠

    2007-01-01

    J. Mather and A. Fathi defined Ma(n)ié set and Aubry set, which are the important invariant sets in positive definite Lagrangian system, in different ways.They use variational principle and Weak KAM theory respectively. In this paper we provide a proof of the equivalence between the two kinds of definitions, and generalize A. Fathi's definition. In the end of the paper, we calculate the Ma(n)é set and Aubry set for a single pendulum system.

  12. Hanford External Dosimetry Technical Basis Manual PNL-MA-842

    Energy Technology Data Exchange (ETDEWEB)

    Rathbone, Bruce A.

    2009-08-28

    The Hanford External Dosimetry Technical Basis Manual PNL-MA-842 documents the design and implementation of the external dosimetry system used at Hanford. The manual describes the dosimeter design, processing protocols, dose calculation methodology, radiation fields encountered, dosimeter response characteristics, limitations of dosimeter design under field conditions, and makes recommendations for effective use of the dosimeters in the field. The manual describes the technical basis for the dosimetry system in a manner intended to help ensure defensibility of the dose of record at Hanford and to demonstrate compliance with 10 CFR 835, DOELAP, DOE-RL, ORP, PNSO, and Hanford contractor requirements. The dosimetry system is operated by PNNL’s Hanford External Dosimetry Program (HEDP) which provides dosimetry services to all Hanford contractors. The primary users of this manual are DOE and DOE contractors at Hanford using the dosimetry services of PNNL. Development and maintenance of this manual is funded directly by DOE and DOE contractors. Its contents have been reviewed and approved by DOE and DOE contractors at Hanford through the Hanford Personnel Dosimetry Advisory Committee (HPDAC) which is chartered and chaired by DOE-RL and serves as means of coordinating dosimetry practices across contractors at Hanford. This manual was established in 1996. Since inception, it has been revised many times and maintained by PNNL as a controlled document with controlled distribution. The first revision to be released through PNNL’s Electronic Records & Information Capture Architecture (ERICA) database was designated Revision 0. Revision numbers that are whole numbers reflect major revisions typically involving changes to all chapters in the document. Revision numbers that include a decimal fraction reflect minor revisions, usually restricted to selected chapters or selected pages in the document.

  13. SDSS-IV MaNGA: Survey Design and Progress

    Science.gov (United States)

    Yan, Renbin; MaNGA Team

    2016-01-01

    The ongoing SDSS-IV/MaNGA Survey will obtain integral field spectroscopy at a resolution of R~2000 with a wavelength coverage from 3,600A to 10,300A for 10,000 nearby galaxies. Within each 3 degree diameter pointing of the 2.5m Sloan Telescope, we deploy 17 hexagonal fiber bundles with sizes ranging from 12 to 32 arcsec in diameter. The bundles are build with 2 arcsec fibers and have a 56% fill factor. During observations, we obtained sets of exposures at 3 different dither positions to achieve near-critical sampling of the effective point spread function, which has a FWHM about 2.5 arcsec, corresponding to 1-2 kpc for the majority of the galaxies targeted. The flux calibration is done using 12 additional mini-fiber-bundles targeting standard stars simultaneously with science targets, achieving a calibration accuracy better than 5% over 90% of the wavelength range. The target galaxies are selected to ensure uniform spatial coverage in units of effective radii for the majority of the galaxies while maximizing spatial resolution. About 2/3 of the sample is covered out to 1.5Re (primary sample) and 1/3 of the sample covered to 2.5Re (secondary sample). The sample is designed to have approximately equal representation from high and low mass galaxies while maintaining volume-limited selection at fixed absolute magnitudes. We obtain an average S/N of 4 per Angstrom in r-band continuum at a surface brightness of 23 AB arcsec-2. With spectral stacking in an elliptical annulus covering 1-1.5Re, our primary sample galaxies have a median S/N of ~60 per Angstrom in r-band.

  14. Festivals de cinéma dans le monde arabe

    Directory of Open Access Journals (Sweden)

    Jean-Michel Frodon

    2013-12-01

    Full Text Available Alors que les deux grands festivals « historiques » du monde arabe, Carthage (JCC et Le Caire, sont entrés en décadence, on assiste depuis le début des années 2000 à une véritable explosion du phénomène festivalier dans le monde arabe. Le pays le plus en pointe est le Maroc, quoique de manière contrastée, avec une manifestation de prestige à Marrakech, et une nuée de petites manifestations. Dans les émirats du Golfe, la multiplication des festivals traduit une stratégie de communication plutôt qu’une volonté de développement culturel. Cette stratégie est fragilisée par la concurrence que se livrent les différents acteurs. Dans les autres pays arabes, on trouve une grande variété de situations sous le signe de la dispersion. Pourtant, l’accumulation de festivals (une centaine dans la région finit par avoir des effets d’ensemble, au-delà des buts, moyens et limites de chacun d’eux. Le phénomène festivalier, bien qu’inscrit dans des agendas locaux ou nationaux, génère de manière plus vaste des réseaux générationnels, financiers, de procédures d’expertise, de processus d’interrelation, géographiques mais aussi entre le cinéma et les autres arts ou médias.

  15. Patent Analysis for Supporting Merger and Acquisition (M&A) Prediction: A Data Mining Approach

    Science.gov (United States)

    Wei, Chih-Ping; Jiang, Yu-Syun; Yang, Chin-Sheng

    M&A plays an increasingly important role in the contemporary business environment. Companies usually conduct M&A to pursue complementarity from other companies for preserving and/or extending their competitive advantages. For the given bidder company, a critical first step to the success of M&A activities is the appropriate selection of target companies. However, existing studies on M&A prediction incur several limitations, such as the exclusion of technological variables in M&A prediction models and the omission of the profile of the respective bidder company and its compatibility with candidate target companies. In response to these limitations, we propose an M&A prediction technique which not only encompasses technological variables derived from patent analysis as prediction indictors but also takes into account the profiles of both bidder and candidate target companies when building an M&A prediction model. We collect a set of real-world M&A cases to evaluate the proposed technique. The evaluation results are encouraging and will serve as a basis for future studies.

  16. Data of evolutionary structure change: 1C7MA-1CTYA [Confc[Archive

    Lifescience Database Archive (English)

    Full Text Available 1C7MA-1CTYA 1C7M 1CTY A A MADPAAGEKVFGK-CKACHKLDG--NDGVGPHLNGVVGR...ID> A 1C7MA HKLDG--NDGVG ...ure> EE -- ure> ATOM 234 CA HIS A ...hain> 1CTY A 1CTYA H...TVEKGGPHKVG ure> ure>

  17. Lessons Learned from M.A. Candidates Pursuing National Board Certification.

    Science.gov (United States)

    Unrau, Norman J.

    2003-01-01

    Presents lessons learned by following M.A. candidates who were supported by California State University, Los Angeles, as they pursued National Board for Professional Teaching Standards (NBPTS) certification. Discusses the introduction of NBPTS certification to M.A. candidates, launching certification projects, and what NBPTS certification…

  18. 33 CFR 165.T01-0542 - Safety Zones: Neptune Deepwater Port, Atlantic Ocean, Boston, MA.

    Science.gov (United States)

    2010-07-01

    ... Port, Atlantic Ocean, Boston, MA. 165.T01-0542 Section 165.T01-0542 Navigation and Navigable Waters... Guard District § 165.T01-0542 Safety Zones: Neptune Deepwater Port, Atlantic Ocean, Boston, MA. (a) Location. The following areas are safety zones: All navigable waters of the United States within a...

  19. European Master's Program in Gerontology (EuMaG): Goals, Curriculum, and Students

    Science.gov (United States)

    Aartsen, Marja

    2011-01-01

    The European Master's Program in Gerontology (EuMaG) started in September 2003 with support from the European Commission. The EuMaG is a modular, 2-year, part-time international training program about the aging process and its societal implications. The multidisciplinary curriculum comprises four domains of gerontology (i.e., social gerontology,…

  20. 78 FR 49918 - Drawbridge Operation Regulation; Taunton River, Fall River and Somerset, MA

    Science.gov (United States)

    2013-08-16

    ... River and Somerset, MA AGENCY: Coast Guard, DHS. ACTION: Final rule. SUMMARY: The Coast Guard has... across the Taunton River, mile 2.1, between Fall River and Somerset, Massachusetts. The bridge owner...) entitled, ``Drawbridge Operation Regulation: Taunton River, Fall River and Somerset, MA'' in the...

  1. European Master's Program in Gerontology (EuMaG): Goals, Curriculum, and Students

    Science.gov (United States)

    Aartsen, Marja

    2011-01-01

    The European Master's Program in Gerontology (EuMaG) started in September 2003 with support from the European Commission. The EuMaG is a modular, 2-year, part-time international training program about the aging process and its societal implications. The multidisciplinary curriculum comprises four domains of gerontology (i.e., social gerontology,…

  2. 46 CFR 308.523 - Application for revision of Open Cargo Policy, Form MA-303.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 8 2010-10-01 2010-10-01 false Application for revision of Open Cargo Policy, Form MA-303. 308.523 Section 308.523 Shipping MARITIME ADMINISTRATION, DEPARTMENT OF TRANSPORTATION EMERGENCY... Application for revision of Open Cargo Policy, Form MA-303. An application for the revision of an Open...

  3. 46 CFR 308.548 - Standard form of underwriting agency agreement for cargo, Form MA-318.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 8 2010-10-01 2010-10-01 false Standard form of underwriting agency agreement for cargo, Form MA-318. 308.548 Section 308.548 Shipping MARITIME ADMINISTRATION, DEPARTMENT OF TRANSPORTATION... underwriting agency agreement for cargo, Form MA-318. This form, which may be obtained from the American...

  4. 46 CFR 308.522 - Collateral deposit fund, letter of transmittal, Form MA-302.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 8 2010-10-01 2010-10-01 false Collateral deposit fund, letter of transmittal, Form MA-302. 308.522 Section 308.522 Shipping MARITIME ADMINISTRATION, DEPARTMENT OF TRANSPORTATION EMERGENCY... Collateral deposit fund, letter of transmittal, Form MA-302. The standard form of letter of transmittal...

  5. 46 CFR 308.521 - Application for Open Cargo Policy, Form MA-301.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 8 2010-10-01 2010-10-01 false Application for Open Cargo Policy, Form MA-301. 308.521 Section 308.521 Shipping MARITIME ADMINISTRATION, DEPARTMENT OF TRANSPORTATION EMERGENCY OPERATIONS WAR... for Open Cargo Policy, Form MA-301. The standard form of application for a War Risk Open Cargo...

  6. 46 CFR 308.546 - Standard optional endorsement No. 1-A, Form MA-316-A.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 8 2010-10-01 2010-10-01 false Standard optional endorsement No. 1-A, Form MA-316-A... Standard optional endorsement No. 1-A, Form MA-316-A. Standard Optional Endorsement No. 1-A limits the... provisions for Open Cargo Policies are contained in Standard Optional Endorsement No. 1, Form...

  7. 77 FR 19573 - Safety Zone; Wedding Fireworks Display, Boston Inner Harbor, Boston, MA

    Science.gov (United States)

    2012-04-02

    ... the January 17, 2008, issue of the Federal Register (73 FR 3316). Public Meeting We do not now plan to... Harbor, Boston, MA AGENCY: Coast Guard, DHS. ACTION: Notice of proposed rulemaking. SUMMARY: The Coast... in the vicinity of Anthony's Pier 4, Boston, MA for a wedding fireworks display. This...

  8. 46 CFR 7.10 - Eastport, ME to Cape Ann, MA.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 1 2010-10-01 2010-10-01 false Eastport, ME to Cape Ann, MA. 7.10 Section 7.10 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY PROCEDURES APPLICABLE TO THE PUBLIC BOUNDARY LINES Atlantic Coast § 7.10 Eastport, ME to Cape Ann, MA. (a) A line drawn from the easternmost extremity of...

  9. 46 CFR 308.519 - Standard optional endorsement No. 2, Form MA-300-B.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 8 2010-10-01 2010-10-01 false Standard optional endorsement No. 2, Form MA-300-B. 308.519 Section 308.519 Shipping MARITIME ADMINISTRATION, DEPARTMENT OF TRANSPORTATION EMERGENCY... Standard optional endorsement No. 2, Form MA-300-B. Standard Optional Endorsement No. 2, which may...

  10. 46 CFR 308.520 - Standard optional endorsement No. 3, Form MA-300-C.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 8 2010-10-01 2010-10-01 false Standard optional endorsement No. 3, Form MA-300-C. 308.520 Section 308.520 Shipping MARITIME ADMINISTRATION, DEPARTMENT OF TRANSPORTATION EMERGENCY... Standard optional endorsement No. 3, Form MA-300-C. Standard Optional Endorsement No. 3, which may...

  11. 46 CFR 308.529 - Surety Bond B, Form MA-309.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 8 2010-10-01 2010-10-01 false Surety Bond B, Form MA-309. 308.529 Section 308.529... Risk Cargo Insurance Ii-Open Policy War Risk Cargo Insurance § 308.529 Surety Bond B, Form MA-309. An Assured who elects to substitute a surety bond for a collateral deposit fund shall submit Form...

  12. 46 CFR 308.518 - Standard optional endorsement No. 1, Form MA-300-A.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 8 2010-10-01 2010-10-01 false Standard optional endorsement No. 1, Form MA-300-A. 308.518 Section 308.518 Shipping MARITIME ADMINISTRATION, DEPARTMENT OF TRANSPORTATION EMERGENCY... Standard optional endorsement No. 1, Form MA-300-A. Standard Optional Endorsement No. 1, which may...

  13. 33 CFR 80.115 - Portland Head, ME to Cape Ann, MA.

    Science.gov (United States)

    2010-07-01

    ... 33 Navigation and Navigable Waters 1 2010-07-01 2010-07-01 false Portland Head, ME to Cape Ann, MA. 80.115 Section 80.115 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY..., MA. (a) Except inside lines specifically described in this section, the 72 COLREGS shall apply on...

  14. Geochemical stratigraphy of submarine lavas (3-5 Ma) from the Flamengos Valley, Santiago, Cape Verde

    DEFF Research Database (Denmark)

    Barker, Abigail K; Holm, Paul Martin; Peate, David W.

    2009-01-01

    into three petrographic and compositional groups; the Flamengos Formation lavas ( 4·6 Ma) dominate the sequence, with the younger Low Si and Coastal groups ( 2·8 Ma) found near the shoreline. Olivine and clinopyroxene compositions and isotopic data for minerals and their host melts indicate disequilibrium...

  15. 42 CFR 422.324 - Payments to MA organizations for graduate medical education costs.

    Science.gov (United States)

    2010-10-01

    ... Medicare Advantage Organizations § 422.324 Payments to MA organizations for graduate medical education costs. (a) MA organizations may receive direct graduate medical education payments for the time that... medical education payments if all of the following conditions are met: (1) The resident spends his or...

  16. Liberal Arts in China's Modern Universities: Lessons from the Great Catholic Educator and Statesman, Ma Xiangbo

    Science.gov (United States)

    Jiang, You Guo

    2012-01-01

    Ma Xiangbo was born in 1840 and became a pioneer of educational reform during the republican period. He was responsible for introducing the idea that science and humanities should be valued equally in liberal arts education, a concept that became key to the model of university education. Ma's view of education combined Western humanism and science…

  17. Implications of progesterone metabolism in MA-10 cells for accurate measurement of the rate of steroidogenesis.

    NARCIS (Netherlands)

    Rommerts, F.F.; King, S.R.; Span, P.N.

    2001-01-01

    In virtually all studies with MA-10 cells, progesterone RIAs have been used to measure steroid synthesis. To test whether progesterone is a stable end product, we investigated the metabolism of added tritiated progesterone and pregnenolone in MA-10 cells over a period of 3 h. Steroids were then extr

  18. 42 CFR 422.314 - Special rules for beneficiaries enrolled in MA MSA plans.

    Science.gov (United States)

    2010-10-01

    ... 42 Public Health 3 2010-10-01 2010-10-01 false Special rules for beneficiaries enrolled in MA MSA... Advantage Organizations § 422.314 Special rules for beneficiaries enrolled in MA MSA plans. (a) Establishment and designation of medical savings account (MSA). A beneficiary who elects coverage under an...

  19. Hanford External Dosimetry Technical Basis Manual PNL-MA-842

    Energy Technology Data Exchange (ETDEWEB)

    Rathbone, Bruce A.

    2010-04-01

    The Hanford External Dosimetry Technical Basis Manual PNL-MA-842 documents the design and implementation of the external dosimetry system used at the U.S. Department of Energy (DOE) Hanford site. The manual describes the dosimeter design, processing protocols, dose calculation methodology, radiation fields encountered, dosimeter response characteristics, limitations of dosimeter design under field conditions, and makes recommendations for effective use of the dosimeters in the field. The manual describes the technical basis for the dosimetry system in a manner intended to help ensure defensibility of the dose of record at Hanford and to demonstrate compliance with requirements of 10 CFR 835, the DOE Laboratory Accreditation Program, the DOE Richland Operations Office, DOE Office of River Protection, DOE Pacific Northwest Office of Science, and Hanford’s DOE contractors. The dosimetry system is operated by the Pacific Northwest National Laboratory (PNNL) Hanford External Dosimetry Program which provides dosimetry services to PNNL and all Hanford contractors. The primary users of this manual are DOE and DOE contractors at Hanford using the dosimetry services of PNNL. Development and maintenance of this manual is funded directly by DOE and DOE contractors. Its contents have been reviewed and approved by DOE and DOE contractors at Hanford through the Hanford Personnel Dosimetry Advisory Committee which is chartered and chaired by DOE-RL and serves as means of coordinating dosimetry practices across contractors at Hanford. This manual was established in 1996. Since its inception, it has been revised many times and maintained by PNNL as a controlled document with controlled distribution. The first revision to be released through PNNL’s Electronic Records & Information Capture Architecture database was designated Revision 0. Revision numbers that are whole numbers reflect major revisions typically involving significant changes to all chapters in the document. Revision

  20. Hanford External Dosimetry Technical Basis Manual PNL-MA-842

    Energy Technology Data Exchange (ETDEWEB)

    Rathbone, Bruce A.

    2011-04-04

    The Hanford External Dosimetry Technical Basis Manual PNL-MA-842 documents the design and implementation of the external dosimetry system used at the U.S. Department of Energy (DOE) Hanford site. The manual describes the dosimeter design, processing protocols, dose calculation methodology, radiation fields encountered, dosimeter response characteristics, limitations of dosimeter design under field conditions, and makes recommendations for effective use of the dosimeters in the field. The manual describes the technical basis for the dosimetry system in a manner intended to help ensure defensibility of the dose of record at Hanford and to demonstrate compliance with requirements of 10 CFR 835, the DOE Laboratory Accreditation Program, the DOE Richland Operations Office, DOE Office of River Protection, DOE Pacific Northwest Office of Science, and Hanford’s DOE contractors. The dosimetry system is operated by the Pacific Northwest National Laboratory (PNNL) Hanford External Dosimetry Program which provides dosimetry services to PNNL and all Hanford contractors. The primary users of this manual are DOE and DOE contractors at Hanford using the dosimetry services of PNNL. Development and maintenance of this manual is funded directly by DOE and DOE contractors. Its contents have been reviewed and approved by DOE and DOE contractors at Hanford through the Hanford Personnel Dosimetry Advisory Committee which is chartered and chaired by DOE-RL and serves as means of coordinating dosimetry practices across contractors at Hanford. This manual was established in 1996. Since its inception, it has been revised many times and maintained by PNNL as a controlled document with controlled distribution. The first revision to be released through PNNL’s Electronic Records & Information Capture Architecture database was designated Revision 0. Revision numbers that are whole numbers reflect major revisions typically involving significant changes to all chapters in the document. Revision

  1. Hanford External Dosimetry Technical Basis Manual PNL-MA-842

    Energy Technology Data Exchange (ETDEWEB)

    Rathbone, Bruce A.

    2007-03-12

    The Hanford External Dosimetry Technical Basis Manual PNL-MA-842 documents the design and implementation of the external dosimetry system used at Hanford. The manual describes the dosimeter design, processing protocols, dose calculation methodology, radiation fields encountered, dosimeter response characteristics, limitations of dosimeter design under field conditions, and makes recommendations for effective use of the dosimeters in the field. The manual describes the technical basis for the dosimetry system in a manner intended to help ensure defensibility of the dose of record at Hanford and to demonstrate compliance with 10 CFR 835, DOELAP, DOE-RL, ORP, PNSO, and Hanford contractor requirements. The dosimetry system is operated by PNNL’s Hanford External Dosimetry Program (HEDP) which provides dosimetry services to all Hanford contractors. The primary users of this manual are DOE and DOE contractors at Hanford using the dosimetry services of PNNL. Development and maintenance of this manual is funded directly by DOE and DOE contractors. Its contents have been reviewed and approved by DOE and DOE contractors at Hanford through the Hanford Personnel Dosimetry Advisory Committee (HPDAC) which is chartered and chaired by DOE-RL and serves as means of coordinating dosimetry practices across contractors at Hanford. This manual was established in 1996. Since inception, it has been revised many times and maintained by PNNL as a controlled document with controlled distribution. Rev. 0 marks the first revision to be released through PNNL’s Electronic Records & Information Capture Architecture (ERICA) database. Revision numbers that are whole numbers reflect major revisions typically involving changes to all chapters in the document. Revision numbers that include a decimal fraction reflect minor revisions, usually restricted to selected chapters or selected pages in the document. Revision Log: Rev. 0 (2/25/2005) Major revision and expansion. Rev. 0.1 (3/12/2007) Minor

  2. Echt und modern? Diskurse über Männlichkeit

    Directory of Open Access Journals (Sweden)

    Florian Kahofer

    2014-09-01

    Full Text Available Der vorliegende Artikel befasst sich mit Repräsentationen von Männlichkeit im österreichischen Lifestyle-Magazin für Männer Wiener. Durch eine korpusbasierte Diskursanalyse wird ein umfassendes Korpus aller Ausgaben des Wieners von Anfang 2002 bis Ende 2012 untersucht. Auf theoretischer Ebene wird dabei eine Verbindung von Kritischer Männlichkeitsforschung (KMF und Feministisch Kritischer Diskursanalyse (FCDA unternommen. Es werden aktuelle Veröffentlichungen zu Kritischer Diskursanalyse und Männlichkeit vorgestellt und diskutiert. Durch den Einsatz einer Konkordanzsoftware werden Konkordanzen des Nomens MANN analysiert. Diese werden allerdings insofern eingeschränkt betrachtet, als nur Nominationen in der Form der häufigsten Adjektiv-Konstruktionen untersucht werden. Die Ergebnisse zeigen, dass neben den Diskursen über Krise und Neue Männlichkeit Themen wie Alter, Körper oder Beziehung auftauchen. Männlichkeit wird als ambivalent und vielfältig dargestellt. Deutungskämpfe um Männlichkeit lassen sich ausmachen.

  3. Synthesis, properties, and biomedical applications of gelatin methacryloyl (GelMA) hydrogels.

    Science.gov (United States)

    Yue, Kan; Trujillo-de Santiago, Grissel; Alvarez, Mario Moisés; Tamayol, Ali; Annabi, Nasim; Khademhosseini, Ali

    2015-12-01

    Gelatin methacryloyl (GelMA) hydrogels have been widely used for various biomedical applications due to their suitable biological properties and tunable physical characteristics. GelMA hydrogels closely resemble some essential properties of native extracellular matrix (ECM) due to the presence of cell-attaching and matrix metalloproteinase responsive peptide motifs, which allow cells to proliferate and spread in GelMA-based scaffolds. GelMA is also versatile from a processing perspective. It crosslinks when exposed to light irradiation to form hydrogels with tunable mechanical properties. It can also be microfabricated using different methodologies including micromolding, photomasking, bioprinting, self-assembly, and microfluidic techniques to generate constructs with controlled architectures. Hybrid hydrogel systems can also be formed by mixing GelMA with nanoparticles such as carbon nanotubes and graphene oxide, and other polymers to form networks with desired combined properties and characteristics for specific biological applications. Recent research has demonstrated the proficiency of GelMA-based hydrogels in a wide range of tissue engineering applications including engineering of bone, cartilage, cardiac, and vascular tissues, among others. Other applications of GelMA hydrogels, besides tissue engineering, include fundamental cell research, cell signaling, drug and gene delivery, and bio-sensing.

  4. Antioxidative effects in vivo and colonization of Lactobacillus plantarum MA2 in the murine intestinal tract.

    Science.gov (United States)

    Tang, Wei; Xing, Zhuqing; Hu, Wei; Li, Chao; Wang, Jinju; Wang, Yanping

    2016-08-01

    Lactobacillus plantarum MA2 was isolated from traditional Chinese Tibet kefir grains, which possess several excellent properties and functions. We previously demonstrated the antioxidant activities of this bacterium in vitro. However, the maintenance and survival of L. plantarum MA2 inside the murine intestinal tract, where it exerts its probiotic properties, and whether its effects are elicited directly on the host remain unknown. Therefore, this study investigated the mechanisms of L. plantarum MA2 in aging mice following D-galactose administration. The levels of malondialdehyde decreased significantly in the L. plantarum MA2 groups after oral ingestion compared to the D-galactose model group, and total antioxidant capacity and glutathione peroxidase and superoxide dismutase activities increased significantly in the serum and liver. We combined fluorescein isothiocyanate labeling and green fluorescent protein expression to dynamically monitor the colonization and distribution of L. plantarum MA2 in the murine intestinal tract. The results indicated that L. plantarum MA2 was detected in the ileum, colon, and feces after single and continuous oral administration at day 21 and was maintained at 10(4)-10(5) CFU/g. These results suggest that L. plantarum MA2 colonizes and survives in the murine intestinal tract to exert its antioxidative effects.

  5. Hanford External Dosimetry Technical Basis Manual PNL-MA-842

    Energy Technology Data Exchange (ETDEWEB)

    Rathbone, Bruce A.

    2010-01-01

    The Hanford External Dosimetry Technical Basis Manual PNL-MA-842 documents the design and implementation of the external dosimetry system used at Hanford. The manual describes the dosimeter design, processing protocols, dose calculation methodology, radiation fields encountered, dosimeter response characteristics, limitations of dosimeter design under field conditions, and makes recommendations for effective use of the dosimeters in the field. The manual describes the technical basis for the dosimetry system in a manner intended to help ensure defensibility of the dose of record at Hanford and to demonstrate compliance with 10 CFR 835, DOELAP, DOE-RL, ORP, PNSO, and Hanford contractor requirements. The dosimetry system is operated by PNNL’s Hanford External Dosimetry Program (HEDP) which provides dosimetry services to all Hanford contractors. The primary users of this manual are DOE and DOE contractors at Hanford using the dosimetry services of PNNL. Development and maintenance of this manual is funded directly by DOE and DOE contractors. Its contents have been reviewed and approved by DOE and DOE contractors at Hanford through the Hanford Personnel Dosimetry Advisory Committee (HPDAC) which is chartered and chaired by DOE-RL and serves as means of coordinating dosimetry practices across contractors at Hanford. This manual was established in 1996. Since its inception, it has been revised many times and maintained by PNNL as a controlled document with controlled distribution. The first revision to be released through PNNL’s Electronic Records & Information Capture Architecture (ERICA) database was designated Revision 0. Revision numbers that are whole numbers reflect major revisions typically involving significant changes to all chapters in the document. Revision numbers that include a decimal fraction reflect minor revisions, usually restricted to selected chapters or selected pages in the document. Maintenance and distribution of controlled hard copies of the

  6. Preserved history of global mean spreading rate: 83 Ma to present

    Science.gov (United States)

    Rowan, Christopher J.; Rowley, David B.

    2017-02-01

    Using an up-to-date global plate rotation model, applied to the endpoints of preserved major spreading ridge isochrons, we have calculated the explicitly reconstructable length-weighted mean global half-spreading rate (HSR), ridge length and area production as a function of time since the end of the Cretaceous Normal Superchron at 83.0 Ma. Our calculations integrate uncertainties in rotation parameters and chron boundary ages with the partial sampling uncertainties arising from progressive subduction of older oceanic lithosphere and its preserved spreading record. This record of directly reconstructable oceanic ridge production provides a well-constrained baseline that can be compared to reconstructions that include the largely unconstrained extrapolated histories of entirely subducted oceanic plates. The directly reconstructable global mean HSR has not varied by more than ±15 per cent about an average rate of 28.4 ± 4.6 mm a-1 since 83 Ma. No long-term secular trend is evident: a maximum global mean half-rate of 32 ± 6 mm a-1 occurred from 33.1 Ma to about 25.8 Ma, with minima of 26 ± 5 mm a-1 between about 56 and 40.2 Ma, and 24 ± 1 mm a-1 since 3.2 Ma. Only this most recent interval has a rate that differs significantly (at ±2σ) from the long-term mean. The global, reconstructable ridge length at 56 Ma decreases by less than 15 per cent relative to the modern ridge system; by 83 Ma it has decreased by 38 per cent. These relatively high preserved ridge fractions mean that the estimated uncertainty due to partial sampling stays roughly equivalent to the estimated rotation model uncertainties, allowing long-term spreading rate variations of >20 per cent since the Late Cretaceous to be ruled out. In contrast, prior to 83 Ma too little oceanic lithosphere is preserved to reliably reconstruct global spreading rates.

  7. MaRIE: an experimental facility concept revolutionizing materials in extremes

    Energy Technology Data Exchange (ETDEWEB)

    Barnes, Cris W [Los Alamos National Laboratory

    2011-01-07

    The Matter-Radiation Interactions in Extremes (MaRIE) project intends to create an experimental facility that will revolutionize the control of materials in extremes. That control extends to extreme regimes where solid material has failed and begins to flow - the regimes of fluid dynamics and turbulent mixing. This presentation introduces the MaRIE facility concept, demonstrates examples of the science case that determine its functional requirements, and kicks-off the discussion of the decadal scientific challenges of mixing in extremes, including those MaRIE might address.

  8. MaRIE: Probing Dynamic Processes in Soft Materials Using Advanced Light Sources

    Energy Technology Data Exchange (ETDEWEB)

    Sykora, Milan [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Kober, Edward Martin [Los Alamos National Lab. (LANL), Los Alamos, NM (United States)

    2016-02-16

    Los Alamos National Laboratory has developed a concept for a new research facility, MaRIE: Matter-Radiation Interactions in Extremes. The key motivation for MaRIE is to develop new experimental capabilities needed to fill the existing gaps in our fundamental understanding of materials important for key National Nuclear Security Agency (NNSA) goals. MaRIE will bring two major new capabilities: (a) the ability to characterize the meso- and microstructure of materials in bulk as well as local dynamic response characteristics, and (b) the ability to characterize how this microstructure evolves under NNSA-relevant conditions and impacts the material’s performance in this regime.

  9. Relaciones de competencia entre el maíz cultivado y las malas hierbas

    OpenAIRE

    Costar Castán, Asunción; Peña-Asín, Javier; Puig Basa, Miriam; Pérez Torres, Antonio; Álvarez Rodríguez, Ángel

    2013-01-01

    En las comarcas maiceras del valle medio del Ebro, uno de los factores de estrés más importantes para el maíz es el causado por las malas hierbas que invaden sus parcelas de cultivo y reducen su rendimiento de grano. Las malas hierbas principalmente compiten con el maíz por el agua, los nutrientes del suelo y la luz solar, sobre todo en las fases iniciales del cultivo, cuando la plántula de maíz se muestra más sensible a esa competencia debido a su reducido sistema radicular y...

  10. RuleMaDrone: A Web-Interface to Visualise Space Usage Rules for Drones

    OpenAIRE

    Trippaers, Aäron

    2015-01-01

    RuleMaDrone, an application developed within this thesis, is presented as a solution to communicate the rules and regulations to drone operators. To provide the solution a framework for drone safety was designed which consists of the rules and regulations, the drone properties and the environmental factors. RuleMaDrone is developed with this framework and thus will provide drone operators with an application which they can use to find a safe and legal fly zone. RuleMaDrone u...

  11. redMaPPer IV: Photometric Membership Identification of Cluster Galaxies with 1% Precision

    CERN Document Server

    Rozo, Eduardo; Becker, Matthew; Reddick, Rachel M; Wechsler, Risa H

    2014-01-01

    In order to study the galaxy population of galaxy clusters with photometric data one must be able to accurately discriminate between cluster members and non-members. The redMaPPer cluster finding algorithm treats this problem probabilistically. Here, we utilize SDSS and GAMA spectroscopic membership rates to validate the redMaPPer membership probability estimates for clusters with $z\\in[0.1,0.3]$. We find small - but correctable - biases, sourced by three different systematics. The first two were expected a priori, namely blue cluster galaxies and correlated structure along the line of sight. The third systematic is new: the redMaPPer template fitting exhibits a non-trivial dependence on photometric noise, which biases the original redMaPPer probabilities when utilizing noisy data. After correcting for these effects, we find exquisite agreement ($\\approx 1\\%$) between the photometric probability estimates and the spectroscopic membership rates, demonstrating that we can robustly recover cluster membership est...

  12. 75 FR 21367 - Advanced Electronics, Inc.; Boston, MA; Notice of Negative Determination on Remand

    Science.gov (United States)

    2010-04-23

    ... Employment and Training Administration Advanced Electronics, Inc.; Boston, MA; Notice of Negative... Department of Labor (Department) for further investigation Former Employees of Advanced Electronics, Inc. v... Adjustment Assistance (ATAA) applicable to workers and former workers of Advanced Electronics, Inc.,...

  13. Contact Aligner 1 (Front and Back Side): Suss Microtec MA6

    Data.gov (United States)

    Federal Laboratory Consortium — Description:CORAL Name: SussMA6This system utilizes 1X contact lithography to transfer photomask patterns onto substrates Specifications / Capabilities:UV broadmand...

  14. Thermoelectric Properties of CexCo4Sb12 Prepared by MA-SPS

    Institute of Scientific and Technical Information of China (English)

    刘科高; 张久兴; 路清梅; 刘丹敏; 张隆; 周美玲

    2004-01-01

    Starting with elementary powders, thermoelectric materials CexCo4Sb12 were prepared by mechanical alloying and spark plasma sintering (MA-SPS). XRD analyses reveal that the expected major phase, named skutterudite was formed in MA process and was kept after SPS. The thermoelectric properties of MA-SPS samples including resistivity, Seebeck coefficient, power factor, thermal conductivity and the dimensionless figure of merit (ZT) were studied by varying Ce content and temperature. Depending on Ce levels, both P and N types of thermoelectric semiconductors were obtained. MA-SPS sintered Ce1.0Co4Sb12 exhibits the highest ZT in the range of 100~500 ℃ and the maximum ZT is found at x=1.0 and 400 ℃.

  15. Comparison of TCeMA and TDMA for Inter-Satellite Communications using OPNET Simulation

    Science.gov (United States)

    Hain, Regina Rosales; Ramanathan, Ram; Bergamo, Marcos; Wallett, Thomas M.

    2003-01-01

    A robust data link protocol, enabling unique physical and MAC layer technologies and sub-network level protocols, is needed in order to take advantage of the full potential of using both TDMA and CDMA in a satellite communication network. A novel MAC layer protocol, TDMA with CDMA-encoding multiple access (TCeMA) integrated with null-steered digital beam-forming spatial multiplexing, is investigated to support flexible spacecraft communications. Abstract models of the TCeMA and TDMA processes are developed in OPNFiT and a comparison of the performances of TCeMA and TDMA in a satellite network simulation are made. TCeMA provides the better connectivity and capacity with respect to TDMA for satellite communication traffic.

  16. An Effective Supervisory Model to Help MA English Students in the Process of Writing Their Thesis

    National Research Council Canada - National Science Library

    Rahmani Sangani, Hamid; Bassir, Seyed Iman; Jalali, Latifah

    2016-01-01

    Conducting a research project and writing up a thesis could be as nearly demanding as it is essential for MA students to achieve their academic goals, particularly in developing world contexts such as Iran...

  17. Assessing the performance of regional landslide early warning models: the EDuMaP method

    National Research Council Canada - National Science Library

    M. Calvello; L. Piciullo

    2015-01-01

    The paper proposes the evaluation of the technical performance of a regional landslide early warning system by means of an original approach, called EDuMaP method, comprising three successive steps...

  18. 78 FR 22423 - Drawbridge Operation Regulations; Taunton River, Fall River and Somerset, MA

    Science.gov (United States)

    2013-04-16

    ... Somerset, MA AGENCY: Coast Guard, DHS. ACTION: Notice of temporary deviation from regulation. SUMMARY: The... Brightman Street Bridge across the Taunton River, mile 1.8, between Fall River and Somerset,...

  19. Astronaut Scott Carpenter on recovery ship U.S.S. Intrepid after MA-7 flight

    Science.gov (United States)

    1962-01-01

    Astronaut M. Scott Carpenter, prime pilot for the Mercury-Atlas 7 (MA-7) mission, arrives aboard the prime recovery ship, U.S.S. Intrepid, during recovery operations following his earth-orbital mission.

  20. "Ma sinna istutaks need lilled punased..." : [luuletused] / [Ptshelovodova, Nadezhda] Muš Nadii ; tlk. Arvo Valton

    Index Scriptorium Estoniae

    Muš Nadii, pseud., 1976-

    2006-01-01

    Sisu: "Ma sinna istutaks need lilled punased..." ; "Ei kõik hinged tõuse taevasse..." ; Kuum öö ; Kas tunned ; Ojamaa ; Magnoolia ; 24.02.2005 ; Päike vaatab tagasi. Luuletused paralleelselt udmurdi ja eesti keeles

  1. EnviroAtlas - New Bedford, MA - One Meter Resolution Urban Land Cover Data (2010) Web Service

    Data.gov (United States)

    U.S. Environmental Protection Agency — This EnviroAtlas web service supports research and online mapping activities related to EnviroAtlas (https://www.epa.gov/enviroatlas). The New Bedford, MA land cover...

  2. EnviroAtlas - New Bedford, MA - Meter-Scale Urban Land Cover (MULC) Data (2010)

    Data.gov (United States)

    U.S. Environmental Protection Agency — The New Bedford, MA Meter-Scale Urban Land Cover (MULC) data were generated from United States Department of Agriculture (USDA) National Agricultural Imagery Program...

  3. The Mesoscale Science of the Matter-Radiation Interactions in Extremes (MaRIE) project

    Energy Technology Data Exchange (ETDEWEB)

    Kippen, Karen Elizabeth [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Montoya, Donald Raymond [Los Alamos National Lab. (LANL), Los Alamos, NM (United States)

    2017-08-17

    The National Nuclear Security Administration (NNSA) requires the ability to understand and test how material structures, defects, and interfaces determine performance in extreme environments such as in nuclear weapons. To do this, MaRIE will be an x-ray source that is laser-like and brilliant with very fl exible and fast pulses to see at weapons-relevant time scales, and with high enough energy to study critical materials. The Department of Energy (DOE) has determined there is a mission need for MaRIE to deliver this capability. MaRIE can use some of the existing infrastructure of the Los Alamos Neutron Science Center (LANSCE) and its accelerator capability. MaRIE will be built as a strategic partnership of DOE national laboratories and university collaborators.

  4. Data of evolutionary structure change: 1EGDC-2R0MA [Confc[Archive

    Lifescience Database Archive (English)

    Full Text Available 1EGDC-2R0MA 1EGD 2R0M C A -------LGFSFEFTEQQKEFQATARKFAREEIIPVAAE...YDKTGEYPVPLIRRAWELGLMNTHIPENCGGLGLGTFDACLISEELAYGCTGVQTAIEGNS-LGQMPIIIAGNDQQKKKYLGRMTEEPLMCAYCVTEPGAGSDVAGIKTKAEKK--GD...EYIINGQKMWITNGGKANWYFLLARSDPDPKAPANKAFTGFIVEADTPGIQIGRKEL-NMGQRCSDTRGIVFEDVKVPKENVLIGDGAGFKVAMGAFD...KERPVVAAGAVGLAQRALDEATKYALERKTFGKLLVEHQAISFMLAEMAMKVELARMSYQRAAWEVDSGRRNTYYASIAKAFAGD... 0 1EGD C

  5. 75 FR 41524 - Cranston Print Works Company, Webster Division, Webster, MA; Cranston Print Works Company...

    Science.gov (United States)

    2010-07-16

    ... Employment and Training Administration Cranston Print Works Company, Webster Division, Webster, MA; Cranston Print Works Company, Corporate Offices, Cranston, RI; Amended Certification Regarding Eligibility To... for Worker Adjustment Assistance on February 6, 2009, applicable to workers of Cranston Print...

  6. The Moderating Effects of Decision-making Preference on M&A Integration Speed and Performance

    DEFF Research Database (Denmark)

    Uzelac, Boris; Bauer, Florian; Matzler, Kurt

    2016-01-01

    This paper illustrates the effects of post-merger integration speed on M&A performance and the moderating role of decision-making preferences. For a better understanding of the effects of integration speed, we separate the role of human and task integration speed. The results, obtained from...... a survey based on 99 M&A transactions with acquirers from the German speaking part of Europe, indicate that fast human integration is beneficial to M&A performance while fast task integration has a significant negative effect. Furthermore our results suggest that the effects of human and task integration...... and positive, while a preference for deliberate decision-making moderates the relation between human integration speed and M&A performance....

  7. [The philosophy & medicinal thought of Dong Mu Lee Jae-Ma].

    Science.gov (United States)

    Jeong, W Y

    1994-01-01

    In this paper, the philosophy and the content of medicinal philosophy of Lee Jae-Ma were illuminated through the history and philosophy of the late Choseon times from 1837 to 1900. Some conclusions were as follows: 1) Lee Jae-Ma was a philosopher as well as a physician, and his philosophical background was well appeared in the book of (Kogchigo). 2) Although the philosophy of Lee Jae-Ma and its terms were derived from the Kyunghakseol of Confucianism, the concept of these terms was different from the Neo-Confucianism of Song Dynasty in China. 3) The four phases of the philosophy of Lee Jae-Ma was originated from the four important trigrams, however, he did not take the meanings of the changes and development of the trigrams in I Ching>, but also took the four components of construction of cosmos similar to the Western theory of four component. ...

  8. 枯萎病菌Foc4侵染后不同香蕉种质中病程相关基因MaTLP和MaBGLU表达水平分析%Expression Analysi s of MaTLP and MaBGLU in Banana Germlasm with Different Resistant Infected by Fusarium oxysporum f. sp. Cubense

    Institute of Scientific and Technical Information of China (English)

    李文彬; 李春强; 孙建波; 彭明

    2015-01-01

    为了阐明不同抗性香蕉种质对枯萎病4号小种(Foc4)侵染的反应机制,本研究从香蕉中克隆到两个与病程相关的基因,类甜蛋白基因(MaTLP)和β-1,3-葡聚糖酶基因(MaBGLU)。对枯萎病菌侵染后MaTLP和MaBG L U转录水平进行实时荧光定理PCR实验分析,结果显示:MaTL P和MaBG L U基因的表达水平在病原菌侵染后随着侵染时间的增加而迅速增加,尤其在病原菌侵染后51 h,MaTLP在抗性种质FHIA-25和GCTCV-119中的绝对表达量远远高于在感病种质巴西蕉中的表达量,表明其在香蕉与病原菌互作中发挥重要的作用;而在抗性种质Rose中,MaTLP和MaBGLU的表达水平远低于在感病种质巴西蕉中的表达量,并且机械损伤与病原菌处理间,基因的表达量相差不大,说明其存在不同的抗性机制。本研究结果表明不同抗性的香蕉种质可能具有不同的抗性机制,可为进行香蕉与枯萎病特异互作机制的研究奠定了基础。%The banana wilt caused by Fusarium oxysporum f. sp. cubense 4 (Foc4) has disastrous impact on banana planting. More research has focused on the pathogen, pathogenesis and disease-resistance mechanism of banana in recent years. To illustrate the interaction mechanism between banana and Foc4, two important resistant genes MaTLP and MaBGLU were investigated based on Real-time PCR. The result demonstrated that the expression level of MaTLP and MaBGLU was gradually increased after inoculation and got their highest level at 51 h in this experiment. MaTLP and MaBGLU played an important role during the interaction between banana and Foc4 in FHIA-25, while MaTL P was necessary for GCTCV-119. As for the resistant Rose banana, the infection was probably inhibited at the early stage due to the lowest expression level of these two genes. The research illustrated that banana had different mechanisms for Rose, FHIA-25 and GCTCV-119 to Foc4. It could be benefit to disclose the

  9. 75 FR 15740 - Valentine Tool and Stamping, Inc.: Norton, MA; Notice of Termination of Investigation

    Science.gov (United States)

    2010-03-30

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF LABOR Employment and Training Administration Valentine Tool and Stamping, Inc.: Norton, MA; Notice of Termination... of Valentine Tool and Stamping, Inc., Norton, Massachusetts. The petitioner has requested that...

  10. Producción de forraje con maíz criollo y maíz híbrido

    Directory of Open Access Journals (Sweden)

    Jorge Elizondo

    2002-01-01

    Full Text Available Con el fin de conocer el rendimiento productivo de forraje de dos cultivares de maíz: híbrido y criollo, evaluados a igual edad y luego en similar estado fisiológico, sembrados a diferentes distancias entre plantas, se llevó a cabo un experimento en la Estación Experimental Alfredo Volio Mata de la Universidad de Costa Rica, ubicada a una altitud de 1542 msnm, con una precipitación media anual de 2050 mm. Se determinó en ambos cultivares, que la producción de materia seca (kg/ha, reflejó un incremento al disminuir la distancia entre plantas. El cultivar repercutió notablemente sobre los rendimientos productivos. Los rendimientos en base seca (kg/ha fueron 30% mayores en maíz criollo que en maíz hí- brido cuando se comparan a una misma edad. Cuando se comparan ambos cultivares en igual estado fisiológico, los rendimientos en base seca (kg/ha son 37% superiores en el cultivar criollo. La altura promedio de la planta fue 1,7 m mayor en el cultivar criollo que en el híbrido. No se encontraron diferencias significativas en cuanto a rendimientos de biomasa verde o seca, ni en cuanto al contenido de materia seca al comparar el maíz criollo por edad y por estado fisiológico.

  11. MaRiMba: A Software Application for Spectral Library-Based MRM Transition List Assembly

    OpenAIRE

    Sherwood, Carly A.; Eastham, Ashley; Lee, Lik Wee; Peterson, Amelia; Eng, Jimmy K.; Shteynberg, David; Mendoza, Luis; Deutsch, Eric W.; Risler, Jenni; Tasman, Natalie; Aebersold, Ruedi; Lam, Henry; Martin, Daniel B

    2009-01-01

    Multiple reaction monitoring mass spectrometry (MRM-MS) is a targeted analysis method that has been increasingly viewed as an avenue to explore proteomes with unprecedented sensitivity and throughput. We have developed a software tool, called MaRiMba, to automate the creation of explicitly defined MRM transition lists required to program triple quadrupole mass spectrometers in such analyses. MaRiMba creates MRM transition lists from downloaded or custom-built spectral libraries, restricts out...

  12. ANALISIS KESULITAN MATEMATIKA SISWA SMA/MA DALAM MENYELESAIKAN SOAL SETARA UN DI KABUPATEN MALUKU TENGAH

    OpenAIRE

    Muhammad Irfan Rumasoreng; Sugiman Sugiman

    2014-01-01

    Tujuan penelitian ini adalah menentukan jenis kesulitan siswa SMA/MA Kabupaten Maluku Tengah dalam menyelesaikan soal setara UN dan faktor yang menyebabkannya. Pendekatan penelitian ini adalah kualitatif deskriptif. Populasi penelitian adalah 1819 siswa kelas XII SMA/MA Program IPA dari 53 sekolah di Kabupaten Maluku Tengah. Sampel berasal dari tujuh sekolah dengan jumlah siswa sebanyak 95 orang. Pengumpulan data dilakukan dengan menggunakan tes tulis berbentuk urai-an dan dilengkapi dengan w...

  13. Myristic Acid (MA) Promotes Adipogenic Gene Expression and the Differentiation of Porcine Intramuscular Adipocyte Precursor Cells

    Institute of Scientific and Technical Information of China (English)

    LU Nai-sheng; ZHANG Yong-liang; JIANG Qing-yan; SHU Gang; XIE Qiu-ping; ZHU Xiao-tong; GAO Ping; ZHOU Gui-xuan; WANG Song-bo; WANG Li-na; XI Qian-yun

    2014-01-01

    Intramuscular fat (IMF) content is considered to be a key factor that affects the marbling, tenderness, juiciness and lfavor of pork. To investigate the effects of myristic acid (MA) on the differentiation of porcine intramuscular adipocytes, cells were isolated from longissimus dorsi muscle (LDM) and treated with 0, 10, 50 or 100μmol L-1 MA. The results showed that MA signiifcantly promotes the differentiation of intramuscular adipocytes in a dose-dependent manner. MA also led to a parallel increase in the expression of peroxisome proliferator activated receptor-γ(PPARγ) and adipose-related genes, such as glucose transporter 1 (GLUT1), lipoprotein lipase (LPL), adipocyte fatty acid binding protein 4 (FABP4/aP2), fatty acid translocase (FAT), acetyl-CoA carboxylaseα(ACCα), adipose triglyceride lipase (ATGL) and fatty acid synthase (FASN). However, no signiifcant effects of MA were observed on the expression of CAAT enhancer binding protein-α(C/EBPα) or hormone sensitive lipase (HSL). The expression of pyruvate dehydrogenase kinase 4 (PDK4) was increased by MA during the early stages of differentiation (day 1-3). In addition, MA also increased the absolute content of C14 (P<0.001) and saturated fatty acids (SFA) (P<0.05) to varying degrees, but no effects were observed on other fatty acids. These results suggest that MA might be able to enhance the IMF content of pork and increase the accumulation of myristic and myristoleic acid in muscle, which might have beneifcial implications for human health.

  14. The Choice of Market Entry Mode: Greenfield Investment, M&A and Joint Venture

    OpenAIRE

    Stähler, Frank; Ryan, Michael; Raff, Horst

    2007-01-01

    Multinationals may enter a host market by different modes of foreign direct investment (FDI). This paper examines the choice of FDI mode, and shows that the profitability of greenfield investment influences this choice not only directly, but also indirectly since it determines the outside option of potential acquisition targets and joint venture partners. In particular, even if greenfield investment is a viable option, the multinational may prefer a joint venture to M&A, and M&A to greenfield...

  15. M&A in the chinese pharmaceutical industry: Shanghai Pharma and SIPI/SZXP case study

    OpenAIRE

    Wang, Jie

    2016-01-01

    JEL Classification: G14, G34 M&As are developing really fast in China, especially in pharmaceutical industry. But the road of M&A is not flat, some enterprises suffered bitter and unnecessary losses because of blind M&A and lack of comprehensive understanding of the target company. Shanghai Pharmaceutical Co., Ltd. (Shanghai Pharma) played an exemplary role for improving industrial concentration, optimizing the organizational structure and rationally allocating resources by means of M&As. ...

  16. 46 CFR 308.530 - Letter requesting increase or decrease in amount of surety bond, Form MA-310.

    Science.gov (United States)

    2010-10-01

    ... surety bond, Form MA-310. 308.530 Section 308.530 Shipping MARITIME ADMINISTRATION, DEPARTMENT OF... Insurance § 308.530 Letter requesting increase or decrease in amount of surety bond, Form MA-310. An endorsement increasing or decreasing the amount of the surety bond, Form MA-310, shall be transmitted to...

  17. 46 CFR 308.525 - Application for decrease in amount of cash collateral fund, Form MA-305.

    Science.gov (United States)

    2010-10-01

    ... fund, Form MA-305. 308.525 Section 308.525 Shipping MARITIME ADMINISTRATION, DEPARTMENT OF... Insurance § 308.525 Application for decrease in amount of cash collateral fund, Form MA-305. Application for decrease in the amount of the cash collateral deposit fund shall be made on Form MA-305, which may...

  18. 46 CFR 308.526 - Certificate for repayment of decrease of collateral deposit fund, Form MA-306.

    Science.gov (United States)

    2010-10-01

    ... deposit fund, Form MA-306. 308.526 Section 308.526 Shipping MARITIME ADMINISTRATION, DEPARTMENT OF... Insurance § 308.526 Certificate for repayment of decrease of collateral deposit fund, Form MA-306. The..., Form MA-306, may be obtained from the American War Risk Agency or MARAD....

  19. 46 CFR 308.535 - Certificate to be attached to final closing report, Form MA-313-B.

    Science.gov (United States)

    2010-10-01

    ... MA-313-B. 308.535 Section 308.535 Shipping MARITIME ADMINISTRATION, DEPARTMENT OF TRANSPORTATION... § 308.535 Certificate to be attached to final closing report, Form MA-313-B. The Standard Form of Certificate, Form MA-313-B, shall be attached to the final closing report after cancellation of the...

  20. 46 CFR 308.531 - Endorsement of surety bond increasing or decreasing amount of coverage, Form MA-311.

    Science.gov (United States)

    2010-10-01

    ... amount of coverage, Form MA-311. 308.531 Section 308.531 Shipping MARITIME ADMINISTRATION, DEPARTMENT OF... Insurance § 308.531 Endorsement of surety bond increasing or decreasing amount of coverage, Form MA-311. The..., Form MA-311, may be obtained from the American War Risk Agency or MARAD....

  1. 75 FR 27056 - Record of Decision for Environmental Impact Statement: New Bedford Regional Airport, New Bedford, MA

    Science.gov (United States)

    2010-05-13

    ... Regional Airport, New Bedford, MA AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Notice of... Manager, Federal Aviation Administration New England, 12 New England Executive Park, Burlington, MA..., Airports Division, 16 New England Executive Park, Burlington, MA. Telephone (781) 238-7613 and New...

  2. On the development of a 15 mA direct current H - multicusp source

    Science.gov (United States)

    Kuo, T.; Yuan, D.; Jayamanna, K.; McDonald, M.; Baartman, R.; Schmor, P.; Dutto, G.

    1996-03-01

    A 15 mA dc H- multicusp source has been developed for injection into a TR30 cyclotron. This source is also used with a 900 kV tandem accelerator to obtain 10 mA protons at 1.8 MeV. The program is an extension of the 5-7 mA dc H- cusp source developed at TRIUMF during 1989-1990. Major efforts include the search for the optimal filament materials, shape, and location; comparison of cusp line confinement and magnetic filtering of electrons at the extraction region; optimization of extraction lense configuration; and upgrading of vacuum and power systems capability. The source is noncesiated and the maximum arc power available is only 5 kW. After the H- beams pass through an electron suppression grid and a 20 mm collimator, we obtained 15 mA with 0.66 π mm mrad 4 rms normalized emittance. At this output the e/H ratio was about 4. The best normalized emittance occurs around 5-7 mA, having a value of 0.37 π mm mrad. Further development in the near future is planned using cesium and multiple apertures in the hope of increasing dc H- currents to 30 mA while holding the normalized emittance below 0.75 π mm mrad.

  3. Correlating The Star Formation Histories Of MaNGA Galaxies With Their Past AGN Activity

    Science.gov (United States)

    Gonzalez Ortiz, Andrea

    2017-01-01

    We investigate active galactic nuclei (AGN) as a primary mechanism affecting star formation in MaNGA galaxies. Using the Pipe3D code, we modeled the stellar population from MaNGA spectra and derived the star formation histories of 53 AGN host galaxies. We seek to compare the star formation histories of the host galaxies of AGN with the ages of their radio lobes to better understand the role of AGN feedback in the star formation histories of MaNGA galaxies. MaNGA (Mapping Nearby Galaxies at APO) is one of the three core programs in the fourth generation Sloan Digital Sky Survey(SDSS). MaNGA will investigate the internal kinematics of nearly 10,000 local galaxies through dithered observations using fiber integral field units (IFUs) that vary in diameter from 12" (19 fibers) to 32" (127 fibers). In this poster, we present initial results on the star formation histories of MaNGA AGN host galaxies. This work was supported by the SDSS Research Experience for Undergraduates program, which is funded by a grant from Sloan Foundation to the Astrophysical Research Consortium.

  4. Periodic modulations controlling Kuznetsov–Ma soliton formation in nonlinear Schrödinger equations

    Energy Technology Data Exchange (ETDEWEB)

    Tiofack, C.G.L., E-mail: glatchio@yahoo.fr [Univ. Lille, CNRS, UMR 8523 – PhLAM – Physique des Lasers Atomes et Molécules, F-59000 Lille (France); Coulibaly, S.; Taki, M. [Univ. Lille, CNRS, UMR 8523 – PhLAM – Physique des Lasers Atomes et Molécules, F-59000 Lille (France); De Bièvre, S.; Dujardin, G. [Univ. Lille, CNRS, UMR 8524 – Laboratoire Paul Painlevé, F-59000 Lille (France); Équipe-Projet Mephysto, INRIA Lille-Nord Europe (France)

    2017-06-28

    We analyze the exact Kuznetsov–Ma soliton solution of the one-dimensional nonlinear Schrödinger equation in the presence of periodic modulations satisfying an integrability condition. We show that, in contrast to the case without modulation, the Kuznetsov–Ma soliton develops multiple compression points whose number, shape and position are controlled both by the intensity of the modulation and by its frequency. In addition, when this modulation frequency is a rational multiple of the natural frequency of the Kuznetsov–Ma soliton, a scenario similar to a nonlinear resonance is obtained: in this case the spatial oscillations of the Kuznetsov–Ma soliton's intensity are periodic. When the ratio of the two frequencies is irrational, the soliton's intensity is a quasiperiodic function. A striking and important result of our analysis is the possibility to suppress any component of the output spectrum of the Kuznetsov–Ma soliton by a judicious choice of the amplitude and frequency of the modulation. - Highlights: • Exact Kuznetsov–Ma soliton solution in presence of periodic coefficients is obtained. • The multiple compression points of the solution are studied. • The quasi-periodicity of the solution is discussed. • The possibility to suppress any component of the spectrum is analyzed.

  5. MaGate Simulator: A Simulation Environment for a Decentralized Grid Scheduler

    Science.gov (United States)

    Huang, Ye; Brocco, Amos; Courant, Michele; Hirsbrunner, Beat; Kuonen, Pierre

    This paper presents a simulator for of a decentralized modular grid scheduler named MaGate. MaGate’s design emphasizes scheduler interoperability by providing intelligent scheduling serving the grid community as a whole. Each MaGate scheduler instance is able to deal with dynamic scheduling conditions, with continuously arriving grid jobs. Received jobs are either allocated on local resources, or delegated to other MaGates for remote execution. The proposed MaGate simulator is based on GridSim toolkit and Alea simulator, and abstracts the features and behaviors of complex fundamental grid elements, such as grid jobs, grid resources, and grid users. Simulation of scheduling tasks is supported by a grid network overlay simulator executing distributed ant-based swarm intelligence algorithms to provide services such as group communication and resource discovery. For evaluation, a comparison of behaviors of different collaborative policies among a community of MaGates is provided. Results support the use of the proposed approach as a functional ready grid scheduler simulator.

  6. GALACTOSAEMIA IN BLACK SOUTH AFRICAN CHILDREN P.J. ...

    African Journals Online (AJOL)

    1999-05-01

    May 1, 1999 ... Objective: To evaluate the clinical and biochemical features of all black ... Design: Prospective laboratory study. .... Also recorded, were biographical data relating to age .... 256,000 live births per annum (Health Systems Trust.

  7. High-resolution reconstructions of Pacific-North America plate motion: 20 Ma to present

    Science.gov (United States)

    DeMets, C.; Merkouriev, S.

    2016-11-01

    We present new rotations that describe the relative positions and velocities of the Pacific and North America plates at 22 times during the past 19.7 Myr, offering ≈1-Myr temporal resolution for studies of the geotectonic evolution of western North America and other plate boundary locations. Derived from ≈18 000 magnetic reversal, fracture zone and transform fault identifications from the Pacific-Antarctic-Nubia-North America plate circuit and the velocities of 935 GPS sites on the Pacific and North America plates, the new rotations and GPS-derived angular velocity indicate that the rate of motion between the two plates increased by ≈70 per cent from 19.7 to 9±1 Ma, but changed by less than 2 per cent since 8 Ma and even less since 4.2 Ma. The rotations further suggest that the relative plate direction has rotated clockwise for most of the past 20 Myr, with a possible hiatus from 9 to 5 Ma. This conflicts with previously reported evidence for a significant clockwise change in the plate direction at ≈8-6 Ma. Our new rotations indicate that Pacific plate motion became obliquely convergent with respect to the San Andreas Fault of central California at 5.2-4.2 Ma, in agreement with geological evidence for a Pliocene onset of folding and faulting in central California. Our reconstruction of the northern Gulf of California at 6.3 Ma differs by only 15-30 km from structurally derived reconstructions after including 3-4 km Myr-1 of geodetically measured slip between the Baja California Peninsula and Pacific plate. This implies an approximate 15-30 km upper bound for plate non-rigidity integrated around the global circuit at 6.3 Ma. A much larger 200±54 km discrepancy between our reconstruction of the northern Gulf of California at 12 Ma and that estimated from structural and marine geophysical observations suggests that faults in northwestern Mexico or possibly west of the Baja California Peninsula accommodated large amounts of obliquely divergent dextral shear

  8. 香蕉MaCAM基因克隆及表达分析%Cloning and Expression Analysis of MaCAM in Banana

    Institute of Scientific and Technical Information of China (English)

    于小萌; 徐碧玉; 刘菊华; 贾彩红; 张建斌; 王甲水; 金志强

    2012-01-01

    A calmodulin gene named MaCAM was obtained by RACE technology based on a fragment from banana's root cDNA library. The full length of this gene was 845 bp and encoded 149 amino acids. The result of bioinformatics showed that this protein is a stable protein with two conserved function domains―EFh, which pI is 4. 12. Compared with other plant calmodulin genes, the identity of MaCAM was more than 90%. Amino acids identity analysis indicated that MaCAM had 99. 33%,96. 71%,98. 00%,98. 66% similarity compared with Oryza sativa var. japonica ,Elaeis guineensis ,Daucus carota and Saccharum offici-narum respectively. This gene had the most familiar genetic relationship with that of S. officinarum. RT-PCR analysis showed that MaCAM was constitutively expressed in roots,stems,leaves,flowers and fruits. The expression level was the highest in root,flower followed in,and was the lowest in leaves.%从香蕉根的cDNA文库中获得了一段香蕉钙调蛋白基因的片段,采用RACE技术获得其全长,命名为MaCAM.该基因全长845 bp,编码149个氨基酸.生物信息学分析表明,该蛋白属稳定蛋白,其等电点为4.12,有2个保守的EFh功能结构域.与已知植物的钙调蛋白基因相比,一致性达90%以上.其中与粳稻、油棕、胡萝卜、甘蔗的CAM编码的氨基酸序列的一致性分别为99.33%、96.71%、98.00%、98.66%.系统进化树比对分析显示,香蕉与甘蔗的亲缘关系最为密切.器官特异性分析表明,MaCAM在香蕉的根、球茎、叶片、花和果实中均有所表达,在根中表达量最高,花中次之,而在叶片中的表达量最低.

  9. Ma tean, et päike liigub : [luuletused] / Hando Runnel

    Index Scriptorium Estoniae

    Runnel, Hando, 1938-

    1998-01-01

    Sisu: Ma tean et päike liigub ; Ma tean, et ma tulen kord jälle ; Jaanipäevaks kõrgeks kasvab rohi ; Luigelaul ; Pühapäev lastepargis ; Kui päike loojub ; Kohvik ; "Kui veel..." ; Muruks kummel, muruks linnurohi ; Ei mullast sul olegi enam suurt lugu ; Vanaema ; Hauakiri ; Testament ; Üks veski seisab vete pääl ; Kui sa tuled ; Töölispoiss ; Sõbrad ; Mõnitus ; Naine naturaalne ; Kõigevägevam ja kõigelahjem ; Kehv kõhn poiss ; Keldrikakand ; Loogikaloksed ; Tume rahvas ; Võllalaul ; Kodu ; Ei ole ma käinud Komorras ; Mäletaja ; Hingede aeg ; Kui pidud on peetud ; Muusikat olgu ; Kaua sa kannatad ; Üle maa, üle mäda ; Jutt ; "Mis on me pääl, kas jumalate viha..." ; Jälle hakkab ; Müüt ; Vähid ; Muuda ennast ; Mõistmine ; Lindprii ; Kolm külameest 1-3 ; Meie õnn on kindel ; Ei saa me läbi Lätita ; Saadik ; Jälle ; Unistus ; Mets on kõrge ; "Marssis majja majuline..." ; "Üks väga vana rahvas..." ; "Ma polegi isa näinud..." ; "Ilus on ikkagi isamaa pale ; "Kiri algab kirikust..." ; "Mehepoegi läheb pätiks..." ; "Isa oli joodik..." "Hiired veavad pabereid..." ; "Talisman on Talli-Mannil..." ; "Täna ma luuletan läbi öö..." ; "Küll ma ootasin sind tollel tuulisel õhtul..." ; "Me liigume loogeldes loojangu poole... 1-10"

  10. Effects of various Prāṇāyāma on cardiovascular and autonomic variables

    Directory of Open Access Journals (Sweden)

    L Nivethitha

    2016-01-01

    Full Text Available Cardiovascular functions are controlled by neural factors, temperature, hormones, etc., Of these, neural factors primarily concern the autonomic nervous system, which plays a major role in maintaining and regulating cardiac functions, e.g., blood pressure and heart rate. Prāṇāyāma is one of the most important yogic practices. There are various review articles on Yoga and its effects but, though Prāṇāyāma is a part of yoga, there is lack of review articles. To the best of our knowledge there is no known review article on effect of various Prāṇāyāma on cardiovascular and autonomic variables. To provide a general overview about the effect of various prāṇāyāma (breathing techniques on cardiovascular and autonomic variables. A narrative review was performed based on the available scientific literature. An electronic data search was performed in Medline/PubMed database to review relevant articles, using keywords such as “Prāṇāyāma, Yogic breathing techniques, Unilateral nostril breathing, Alternate nostril breathing, Kapalbhati, Bhastrika and Bhramari Pranayama”. All the relevant articles published from 1988 to 06-04-2016 were included in this review. Slow type of yogic breathing technique was reported to produce beneficial effect on cardiovascular and autonomic variables while fast breathing techniques do not produce such effects. There is lack of consistency in the results of specific nostril yogic breathing techniques and the mechanisms behind the effects of various prāṇāyāma. This review suggests that different types of Prāṇāyāma techniques produce different effects and the mechanisms behind these effects are not fully understood.

  11. History of Asian eolian input to the Sea of Japan since 15 Ma: Links to Tibetan uplift or global cooling?

    Science.gov (United States)

    Shen, Xingyan; Wan, Shiming; France-Lanord, Christian; Clift, Peter D.; Tada, Ryuji; Révillon, Sidonie; Shi, Xuefa; Zhao, Debo; Liu, Yanguang; Yin, Xuebo; Song, Zehua; Li, Anchun

    2017-09-01

    We present high-resolution analyses of clay mineral assemblages combined with analysis of Sr-Nd-Pb isotopic compositions of the history of its source region. Our study presents for the first time a continuous, high-resolution record that highlights the four-step drying of Central Asia that occurred at ∼11.8 Ma, 8 Ma, 3.5 Ma and 1.2 Ma. Considered the nature and timing of major climatic and tectonic events in Asia, we conclude that the strengthened aridification of Central Asia starting at ∼11.8 Ma was possibly driven by the combined effect of Tibetan surface uplift and global cooling, whereas the rapid drying at ∼8 Ma was caused primarily by the uplift of the northern Tibetan Plateau. In contrast, global cooling, overwhelming the influence of Tibetan Plateau uplift, has become the primary control on Central Asia aridification since ∼3.5 Ma.

  12. Subduction of the South Chile active spreading ridge: A 17 Ma to 3 Ma magmatic record in central Patagonia (western edge of Meseta del Lago Buenos Aires, Argentina)

    Science.gov (United States)

    Boutonnet, E.; Arnaud, N.; Guivel, C.; Lagabrielle, Y.; Scalabrino, B.; Espinoza, F.

    2010-01-01

    The Chile Triple Junction is a natural laboratory to study the interactions between magmatism and tectonics during the subduction of an active spreading ridge beneath a continent. The MLBA plateau (Meseta del Lago Buenos Aires) is one of the Neogene alkali basaltic plateaus located in the back-arc region of the Andean Cordillera at the latitude of the current Chile Triple Junction. The genesis of MLBA can be related with successive opening of slabs windows beneath Patagonia: within the subducting Nazca Plate itself and between the Nazca and Antarctic plates. Detailed 40Ar/ 39Ar dating and geochemical analysis of bimodal magmatism from the western flank of the MLBA show major changes in the back-arc magmatism which occurred between 14.5 Ma and 12.5 Ma with the transition from calc-alkaline lavas (Cerro Plomo) to alkaline lavas (MLBA) in relation with slab window opening. In a second step, at 4-3 Ma, alkaline felsic intrusions were emplaced in the western flank of the MLBA coevally with the MLBA basalts with which they are genetically related. These late OIB-like alkaline to transitional basalts were generated by partial melting of the subslab asthenosphere of the subducting Nazca plate during the opening of the South Chile spreading ridge-related slab window. These basalts differentiated with small amounts of assimilation in shallow magma chambers emplaced along transtensional to extensional zones. The close association of bimodal magmatism with extensional tectonic features in the western MLBA is a strong support to the model of Patagonian collapse event proposed to have taken place between 5 and 3 Ma as a consequence of the presence of the asthenospheric window (SCR-1 segment of South Chile Ridge) below the MLBA area.

  13. Spontaneous atopic dermatitis-like symptoms in a/a ma ft/ma ft/J flaky tail mice appear early after birth.

    Directory of Open Access Journals (Sweden)

    Magdalini Kypriotou

    Full Text Available Loss-of-function mutations in human profilaggrin gene have been identified as the cause of ichthyosis vulgaris (IV, and as a major predisposition factor for atopic dermatitis (AD. Similarly, flaky tail (a/a ma ft/ma ft/J mice were described as a model for IV, and shown to be predisposed to eczema. The aim of this study was to correlate the flaky tail mouse phenotype with human IV and AD, in order to dissect early molecular events leading to atopic dermatitis in mice and men, suffering from filaggrin deficiency. Thus, 5-days old flaky tail pups were analyzed histologically, expression of cytokines was measured in skin and signaling pathways were investigated by protein analysis. Human biopsies of IV and AD patients were analyzed histologically and by real time PCR assays. Our data show acanthosis and hyperproliferation in flaky tail epidermis, associated with increased IL1β and thymic stromal lymphopoietin (TSLP expression, and Th2-polarization. Consequently, NFκB and Stat pathways were activated, and IL6 mRNA levels were increased. Further, quantitative analysis of late epidermal differentiation markers revealed increased Small proline-rich protein 2A (Sprr2a synthesis. Th2-polarization and Sprr2a increase may result from high TSLP expression, as shown after analysis of 5-days old K14-TSLP tg mouse skin biopsies. Our findings in the flaky tail mouse correlate with data obtained from patient biopsies of AD, but not IV. We propose that proinflammatory cytokines are responsible for acanthosis in flaky tail epidermis, and together with the Th2-derived cytokines lead to morphological changes. Accordingly, the a/a ma ft/ma ft/J mouse model can be used as an appropriate model to study early AD onset associated with profilaggrin deficiency.

  14. Spontaneous atopic dermatitis-like symptoms in a/a ma ft/ma ft/J flaky tail mice appear early after birth.

    Science.gov (United States)

    Kypriotou, Magdalini; Boéchat, Cloé; Huber, Marcel; Hohl, Daniel

    2013-01-01

    Loss-of-function mutations in human profilaggrin gene have been identified as the cause of ichthyosis vulgaris (IV), and as a major predisposition factor for atopic dermatitis (AD). Similarly, flaky tail (a/a ma ft/ma ft/J) mice were described as a model for IV, and shown to be predisposed to eczema. The aim of this study was to correlate the flaky tail mouse phenotype with human IV and AD, in order to dissect early molecular events leading to atopic dermatitis in mice and men, suffering from filaggrin deficiency. Thus, 5-days old flaky tail pups were analyzed histologically, expression of cytokines was measured in skin and signaling pathways were investigated by protein analysis. Human biopsies of IV and AD patients were analyzed histologically and by real time PCR assays. Our data show acanthosis and hyperproliferation in flaky tail epidermis, associated with increased IL1β and thymic stromal lymphopoietin (TSLP) expression, and Th2-polarization. Consequently, NFκB and Stat pathways were activated, and IL6 mRNA levels were increased. Further, quantitative analysis of late epidermal differentiation markers revealed increased Small proline-rich protein 2A (Sprr2a) synthesis. Th2-polarization and Sprr2a increase may result from high TSLP expression, as shown after analysis of 5-days old K14-TSLP tg mouse skin biopsies. Our findings in the flaky tail mouse correlate with data obtained from patient biopsies of AD, but not IV. We propose that proinflammatory cytokines are responsible for acanthosis in flaky tail epidermis, and together with the Th2-derived cytokines lead to morphological changes. Accordingly, the a/a ma ft/ma ft/J mouse model can be used as an appropriate model to study early AD onset associated with profilaggrin deficiency.

  15. y comercialización de maíz de Sinaloa

    Directory of Open Access Journals (Sweden)

    José Alberto García Salazar

    2006-01-01

    Full Text Available La política comercial instrumentada por el Gobierno de México dirigida al mercado de maíz se ha caracterizado por la autorización de importaciones libres de arancel superiores a la cuota establecida en el Tratado de Libre Comercio de América del Norte. Con el objetivo de analizar cómo esta política podría afectar la comercialización de la producción de maíz de Sinaloa, se usó un modelo de distribución de la producción del grano que incorpora características espaciales e intertemporales. Los resultados indican que si el consumo nacional real de maíz fuera menor en 10%, respecto al consumo nacional aparente, las mayores importaciones determinarían que 954 mil toneladas de la producción de la entidad no pudrían comercializarse. Debido a que esta situación resta competitividad al productor de maíz, puesto que la producción no comercializada tiene que almacenarse, los productores sinaloenses deberán estar pendientes y vigilar las decisiones del Gobierno en materia de cupos de importación de maíz.

  16. Glaciation and topographic evolution of the Central Patagonian Andes since 6 Ma

    Science.gov (United States)

    Christeleit, E. C.; Laemel, R.; De Wolf, W. E.; Shuster, D. L.; Brandon, M. T.

    2013-12-01

    New and existing thermochronological data are used to model glacial erosion and topographic evolution of the central Patagonian Andes (~47S) over the last 6 Ma. The modern Andes are cut by large valleys and fjords with local valley relief of at least 2.5 km. It is currently thought that a formerly uniformly high Andes was 'buzzed' down to the elevation of the equilibrium line altitude, presumably in the last 2 Ma concurrent with late Cenozoic global cooling. However, studies of glacial debris show that glaciers were present in Patagonia as early as 6 Ma. The extent of these early glaciations is unclear, but recent work suggests that glacial valleys in the central Patagonian Andes were carved at a steady rate beginning at 6 Ma, implying that valley incision may be an important process in the topographic evolution of glaciated mountain ranges, rather than cirque retreat. To understand how valley relief has formed in the Andes, we dated 30 samples from Steffen Fjord in Chile using apatite (U-Th)/He thermochronology. We use this new data and existing thermochronological data in the region to estimate the topographic form of the central Andes at 6 Ma and model how the valley relief has evolved since the initiation of glaciation using Pecube.

  17. Using superconducting undulator for enhanced imaging capabilities of MaRIE

    Energy Technology Data Exchange (ETDEWEB)

    Yampolsky, Nikolai [Los Alamos National Lab. (LANL), Los Alamos, NM (United States)

    2016-09-22

    MaRIE x-ray free electron laser (FEL) is envisioned to deliver a burst of closely spaced in time pulses for enabling the capability of studying the dynamic processes in a sample. MaRIE capability can be largely enhanced using the superconducting undulator, which has the capability of doubling its period. This technology will allow reaching the photon energy as low as ~200-500 eV. As a result, the MaRIE facility will have a broader photon energy range enabling a larger variety of experiments. The soft x-ray capability is more likely to achieve the 3D imaging of dynamic processes in noncrystal materials than the hard x-ray capability alone.

  18. Earth's youngest exposed granite and its tectonic implications: the 10-0.8 Ma Kurobegawa Granite.

    Science.gov (United States)

    Ito, Hisatoshi; Yamada, Ryuji; Tamura, Akihiro; Arai, Shoji; Horie, Kenji; Hokada, Tomokazu

    2013-01-01

    Although the quest for Earth's oldest rock is of great importance, identifying the youngest exposed pluton on Earth is also of interest. A pluton is a body of intrusive igneous rock that crystallized from slowly cooling magma at depths of several kilometers beneath the surface of the Earth. Therefore, the youngest exposed pluton represents the most recent tectonic uplift and highest exhumation. The youngest exposed pluton reported to date is the Takidani Granodiorite (~ 1.4 Ma) in the Hida Mountain Range of central Japan. Using LA-ICP-MS and SHRIMP U-Pb zircon dating methods, this study demonstrates that the Kurobegawa Granite, also situated in the Hida Mountain Range, is as young as ~ 0.8 Ma. In addition, data indicate multiple intrusion episodes in this pluton since 10 Ma with a ~ 2-million-year period of quiescence; hence, a future intrusion event is likely within 1 million years.

  19. Development and tests of fast 1-MA linear transformer driver stages

    Directory of Open Access Journals (Sweden)

    A. A. Kim

    2009-05-01

    Full Text Available In this article we present the design and test results of the most powerful, fast linear transformer driver (LTD stage developed to date. This 1-MA LTD stage consists of 40 parallel RLC (resistor R, inductor L, and capacitor C circuits called “bricks” that are triggered simultaneously; it is able to deliver ∼1  MA current pulse with a rise time of ∼100  ns into the ∼0.1-Ohm matched load. The electrical behavior of the stage can be predicted by using a simple RLC circuit, thus simplifying the designing of various LTD-based accelerators. Five 1-MA LTD stages assembled in series into a module have been successfully tested with both resistive and vacuum electron-beam diode loads.

  20. Maíz: Alimento fundamental en las tradiciones y costumbres mexicanas

    Directory of Open Access Journals (Sweden)

    José de Jesús Cuevas Mejía

    2014-01-01

    Full Text Available El siguiente trabajo busca recalcar la importancia del maíz para el pueblo mexicano, que con el paso de los años ha logrado mantener su identidad no en vano por la fuerza y majestuosidad de sus tradiciones y costumbres. Es cierto que hoy en día es la base de la alimentación de muchas familias a lo largo del territorio de México, en cada hogar a la hora del almuerzo, la comida e incluso la merienda, el maíz está presente en una gran variedad de formas, texturas y colores. Esto nos hace pensar ¿Qué sería de las fiestas en México sin la presencia del maíz, que año con año se llevan a cabo por todo el territorio?

  1. Gas Kinematics In and Around Edge-on Galaxies from MaNGA Observations

    Science.gov (United States)

    Bizyaev, D.

    2016-06-01

    Mapping Nearby Galaxies at APO (MaNGA) is a massive Integral Field Unit survey of a large number of relatively nearby galaxies that started in 2014 as a part of SDSS-IV at the Apache Point Observatory. After the first year of observations MaNGA has obtained IFU spectra of about a thousand of objects, with several dozens of edge-on galaxies among them. The two-dimensional spectra help us constrain parameters of galactic components with superior rotation curves. There is a significant fraction of galaxies in which the extra-planar gas emission is confidently detected. The extra-planar gas velocity fields in several galaxies show signs of lagging rotation with respect to the gas motion close to the galactic plane. We show progress of MaNGA survey in observations of edge-on galaxies and discuss their impact on our understanding of gas kinematics in and around spiral galaxies after finishing the survey.

  2. MA-core loaded untuned RF compression cavity for HIRFL-CSR

    Science.gov (United States)

    Mei, Li-rong; Xu, Zhe; Yuan, You-jin; Jin, Peng; Bian, Zhi-bin; Zhao, Hong-wei; Xia, Jia-wen

    2012-01-01

    To meet the requirements of high energy density physics and plasma physics research at HIRFL-CSR the goal of achieving a higher accelerating gap voltage was proposed. Therefore, a magnetic alloy (MA)-core loaded radio frequency (RF) cavity that can provide a higher accelerating gap voltage compared to standard ferrite loaded cavities has been studied at IMP. In order to select the proper magnetic alloy material to load the RF compression cavity, measurements of four different kinds of sample MA-cores have been carried out. By testing the small cores, the core composition was selected to obtain the desired performance. According to the theoretical calculation and simulation, which show reasonable consistency for the MA-core loaded cavity, the desired performance can be achieved. Finally about 1000 kW power will be needed to meet the requirements of 50 kV accelerating gap voltage by calculation.

  3. Non-isothermal crystallization kinetics and thermal behaviour of PA12/SEBS-g-MA blends

    Indian Academy of Sciences (India)

    Khushboo Rinawa; S N Maiti; R Sonnier; J-M Lopez Cuesta

    2015-09-01

    The thermal behaviour and crystallization kinetics of PA12/SEBS-g-MA blends were investigated under non-isothermal and isothermal conditions using thermogravimetric analysis and differential scanning calorimetry, respectively. The macrokinetic model given by Avrami was used to analyse both the nonisothermal and isothermal crystallization kinetics of the blends. The value of the Avrami exponent during non-isothermal crystallization predicted that pure PA12 and PA12/SEBS-g-MA blends show spherulitic growth with random nucleation of crystal structures as the n-values lie between 3 and 4. The slight nucleating effect of SEBS-g-MA was showed by nucleating activity calculated by the Dobreva and Gutzowa method.

  4. Paleoceanographic evolution recorded in the northern South China Sea since 4 Ma

    Institute of Scientific and Technical Information of China (English)

    HUANG Baoqi; JIAN Zhimin; WANG Pinxian

    2005-01-01

    Upper water structure over the last 4 million years in the northern South China Sea (SCS) was reconstructed by sea surface temperature (SST) and primary productivity estimated by changes in the abundance of planktonic foraminifer, planktonic foraminifer transfer function, and the accumulation rate of benthic foraminifera. Results of SST and primary productivity show that SST gradually decreased since 4 Ma, but differential seasonal temperature and primary productivity increased in steps mainly at about 3.1, 2.7, 2.1, 1.6, 0.9 and 0.5 Ma. Comparison with tectonics and orbital variations indicates that phased rising of the Tibet since 3.6 Ma, closing of Panama and Indonesian seaways, and orbital changes were responsible for the changes of upper water structure in the SCS, respectively.

  5. Molecular mechanisms and in vitro antioxidant effects of Lactobacillus plantarum MA2.

    Science.gov (United States)

    Tang, Wei; Xing, Zhuqing; Li, Chao; Wang, Jinju; Wang, Yanping

    2017-04-15

    Lactobacillus plantarum MA2 was isolated from Chinese traditional Tibetan kefir grains. The antioxidant activities in vitro of this strain were evaluated extensively. The results showed that L. plantarum MA2 can tolerate hydrogen peroxide up to 2.0mM, and its fermentate (fermented supernatant, intact cell and cell-free extract) had strong reducing capacities, lipid peroxidation inhibition capacities, Fe(2+)-chelating abilities, as well as various free radical scavenging capacities. Additionally, both the fermented supernatant and cell homogenate exhibited glutathione peroxidase activity and superoxide dismutase activity. In order to investigate the antioxidant mechanism of L. plantarum MA2 at the molecular level, eight antioxidant-related genes were identified, and further analyzed. Three groups of genes cat, gshR and npx, were found up-regulated under H2O2 challenge.

  6. Comparative study of the wear resistance of Al{sub 2}O{sub 3}-coated MA956 superalloy

    Energy Technology Data Exchange (ETDEWEB)

    Canahua Loza, H.; Escudero rincon, M. L.; Ruiz Fernandez, J. [Centro Nacional de Investigaciones Metalurgicas CENIM. Madrid (Spain)

    2000-07-01

    Preoxidation of the MA956 superalloy, proposed as prosthetic biomaterial, generates a compact and inert {alpha}-alumina surface layer. The aim of this study is to assess the wear resistance provided by this alumina layer on the MA956 alloy in comparison with the same coated alloy and versus high density polyethylene. Comparative wear tests were carried out in both dry and wet conditions using the couples MA956/MA956, MA956/UHMWPE (ultra high molecular weight polyethylene) and 316LVM/UHMWPE. The results corresponding to the couples MA956/MA956, with and without alumina layer, show that the load has more significant effect than the rotation speed on the weight loss and on the roughness. On the other hand the alumina surface layer provides a clear wear protection. The weight losses of the MA956 specimen in this couple are ten times lower when testing under wet conditions than under dry conditions. The MA956/UHMWPE couple behaves much better than the 316LVM/UHMWPE, as it presents the lowest values of friction coefficient and weight losses of the MA956 specimen. These are only detectable after 70,000 cycles under a 70 MPa contact pressure. This couple offers the best guarantee of a prolonged service life for articulated parts in a prosthesis. (Author) 18 refs.

  7. Ecological change in the lower Omo Valley around 2.8 Ma.

    Science.gov (United States)

    Bibi, Faysal; Souron, Antoine; Bocherens, Hervé; Uno, Kevin; Boisserie, Jean-Renaud

    2013-02-23

    Late Pliocene climate changes have long been implicated in environmental changes and mammalian evolution in Africa, but high-resolution examinations of the fossil and climatic records have been hampered by poor sampling. By using fossils from the well-dated Shungura Formation (lower Omo Valley, northern Turkana Basin, southern Ethiopia), we investigate palaeodietary changes in one bovid and in one suid lineage from 3 to 2 Ma using stable isotope analysis of tooth enamel. Results show unexpectedly large increases in C(4) dietary intake around 2.8 Ma in both the bovid and suid, and possibly in a previously reported hippopotamid species. Enamel δ(13)C values after 2.8 Ma in the bovid (Tragelaphus nakuae) are higher than recorded for any living tragelaphin, and are not expected given its conservative dental morphology. A shift towards increased C(4) feeding at 2.8 Ma in the suid (Kolpochoerus limnetes) appears similarly decoupled from a well-documented record of dental evolution indicating gradual and progressive dietary change. The fact that two, perhaps three, disparate Pliocene herbivore lineages exhibit similar, and contemporaneous changes in dietary behaviour suggests a common environmental driver. Local and regional pollen, palaeosol and faunal records indicate increased aridity but no corresponding large and rapid expansion of grasslands in the Turkana Basin at 2.8 Ma. Our results provide new evidence supporting ecological change in the eastern African record around 2.8 Ma, but raise questions about the resolution at which different ecological proxies may be comparable, the correlation of vegetation and faunal change, and the interpretation of low δ(13)C values in the African Pliocene.

  8. Ma-LMM01 infecting toxic Microcystis aeruginosa illuminates diverse cyanophage genome strategies.

    Science.gov (United States)

    Yoshida, Takashi; Nagasaki, Keizo; Takashima, Yukari; Shirai, Yoko; Tomaru, Yuji; Takao, Yoshitake; Sakamoto, Shigetaka; Hiroishi, Shingo; Ogata, Hiroyuki

    2008-03-01

    Cyanobacteria and their phages are significant microbial components of the freshwater and marine environments. We identified a lytic phage, Ma-LMM01, infecting Microcystis aeruginosa, a cyanobacterium that forms toxic blooms on the surfaces of freshwater lakes. Here, we describe the first sequenced freshwater cyanomyovirus genome of Ma-LMM01. The linear, circularly permuted, and terminally redundant genome has 162,109 bp and contains 184 predicted protein-coding genes and two tRNA genes. The genome exhibits no colinearity with previously sequenced genomes of cyanomyoviruses or other Myoviridae. The majority of the predicted genes have no detectable homologues in the databases. These findings indicate that Ma-LMM01 is a member of a new lineage of the Myoviridae family. The genome lacks homologues for the photosynthetic genes that are prevalent in marine cyanophages. However, it has a homologue of nblA, which is essential for the degradation of the major cyanobacteria light-harvesting complex, the phycobilisomes. The genome codes for a site-specific recombinase and two prophage antirepressors, suggesting that it has the capacity to integrate into the host genome. Ma-LMM01 possesses six genes, including three coding for transposases, that are highly similar to homologues found in cyanobacteria, suggesting that recent gene transfers have occurred between Ma-LMM01 and its host. We propose that the Ma-LMM01 NblA homologue possibly reduces the absorption of excess light energy and confers benefits to the phage living in surface waters. This phage genome study suggests that light is central in the phage-cyanobacterium relationships where the viruses use diverse genetic strategies to control their host's photosynthesis.

  9. The Data Reduction Pipeline for the SDSS-IV MaNGA IFU Galaxy Survey

    Science.gov (United States)

    Law, David R.; Cherinka, Brian; Yan, Renbin; Andrews, Brett H.; Bershady, Matthew A.; Bizyaev, Dmitry; Blanc, Guillermo A.; Blanton, Michael R.; Bolton, Adam S.; Brownstein, Joel R.; Bundy, Kevin; Chen, Yanmei; Drory, Niv; D'Souza, Richard; Fu, Hai; Jones, Amy; Kauffmann, Guinevere; MacDonald, Nicholas; Masters, Karen L.; Newman, Jeffrey A.; Parejko, John K.; Sánchez-Gallego, José R.; Sánchez, Sebastian F.; Schlegel, David J.; Thomas, Daniel; Wake, David A.; Weijmans, Anne-Marie; Westfall, Kyle B.; Zhang, Kai

    2016-10-01

    Mapping Nearby Galaxies at Apache Point Observatory (MaNGA) is an optical fiber-bundle integral-field unit (IFU) spectroscopic survey that is one of three core programs in the fourth-generation Sloan Digital Sky Survey (SDSS-IV). With a spectral coverage of 3622-10354 Å and an average footprint of ˜500 arcsec2 per IFU the scientific data products derived from MaNGA will permit exploration of the internal structure of a statistically large sample of 10,000 low-redshift galaxies in unprecedented detail. Comprising 174 individually pluggable science and calibration IFUs with a near-constant data stream, MaNGA is expected to obtain ˜100 million raw-frame spectra and ˜10 million reduced galaxy spectra over the six-year lifetime of the survey. In this contribution, we describe the MaNGA Data Reduction Pipeline algorithms and centralized metadata framework that produce sky-subtracted spectrophotometrically calibrated spectra and rectified three-dimensional data cubes that combine individual dithered observations. For the 1390 galaxy data cubes released in Summer 2016 as part of SDSS-IV Data Release 13, we demonstrate that the MaNGA data have nearly Poisson-limited sky subtraction shortward of ˜8500 Å and reach a typical 10σ limiting continuum surface brightness μ = 23.5 AB arcsec-2 in a five-arcsecond-diameter aperture in the g-band. The wavelength calibration of the MaNGA data is accurate to 5 km s-1 rms, with a median spatial resolution of 2.54 arcsec FWHM (1.8 kpc at the median redshift of 0.037) and a median spectral resolution of σ = 72 km s-1.

  10. Exploration of Reactivity of Eu(TTA)2(phen)(MA)

    Institute of Scientific and Technical Information of China (English)

    2006-01-01

    The reactivity of Eu(TTA)2(phen)(MA) (HTTA=2-thenoyltrifluoroacetone, MA=maleic anhydride) was studied. A series of products were prepared by direct polymerization, suspension polymerization, and alternate suspension and solution copolymerization with the styrene. And then we reactivity of these products were studied. The complexes were investigated and characterized by X-ray Diffraction (XRD), gel permeation chromatography (GPC) and fluorescence spectrophotometer. Although high polymerization degree is not found in the exploration of reactivity, it is found that the fluorescent intensity of complexes prepared by suspension polymerization increases significantly compared with the original particles, which is five times higher than that of the pure rare earth complex.

  11. Maíz: Alimento fundamental en las tradiciones y costumbres mexicanas

    OpenAIRE

    José de Jesús Cuevas Mejía

    2014-01-01

    El siguiente trabajo busca recalcar la importancia del maíz para el pueblo mexicano, que con el paso de los años ha logrado mantener su identidad no en vano por la fuerza y majestuosidad de sus tradiciones y costumbres. Es cierto que hoy en día es la base de la alimentación de muchas familias a lo largo del territorio de México, en cada hogar a la hora del almuerzo, la comida e incluso la merienda, el maíz está presente en una gran variedad de formas, texturas y colores. Esto nos hace pensar ...

  12. Producción de Aflatoxinas en Maíz in vitro

    OpenAIRE

    Carlos Manuel Bucio Villalobos; Juan José Peña Cabriales; Doralinda Guzmán de Peña

    2001-01-01

    Bucio-Villalobos, C.M., Peña-Cabriales, J.J. y Guzmán-de-Peña,D. 2001. Producción de Aflatoxinas en Maíz in vitro. Revista Mexicana de Fitopatología 19:218-222.El maíz en México, fundamentalmente para consumo humano,es almacenado durante tiempos variables y en diversas condiciones ambientales que favorecen la infestación pori nsectos y hongos. La capacidad toxigénica de estos últimos determina el interés de conocer su comportamiento durante el almacenamiento. En el presente estudio se determ...

  13. Emittance improvement efforts on the 15-20 mA dc H- multicusp source.

    Science.gov (United States)

    Jia, Xianlu; Zhang, Tianjue; Zheng, Xia; Zhang, Suping; Zou, Jian; Lin, Jun

    2010-02-01

    A 15 mA beam from the 15-20 mA dc H(-) multicusp source has been obtained at China Institute of Atomic Energy. In order to improve the emittance of extracted beam from this new multicusp source, some measures have been taken, i.e., increasing the length of the ion source body, improving the vacuum in the extraction area, injecting cesium vapor into the ion source, etc. The hardware, including the lengthened source body, the improved back cover and cesium heating system, and the extraction vacuum box, will be described. Initial results for these efforts aimed at emittance improvement will also be given in the paper.

  14. Emittance improvement efforts on the 15-20 mA dc H- multicusp sourcea)

    Science.gov (United States)

    Jia, Xianlu; Zhang, Tianjue; Zheng, Xia; Zhang, Suping; Zou, Jian; Lin, Jun

    2010-02-01

    A 15 mA beam from the 15-20 mA dc H- multicusp source has been obtained at China Institute of Atomic Energy. In order to improve the emittance of extracted beam from this new multicusp source, some measures have been taken, i.e., increasing the length of the ion source body, improving the vacuum in the extraction area, injecting cesium vapor into the ion source, etc. The hardware, including the lengthened source body, the improved back cover and cesium heating system, and the extraction vacuum box, will be described. Initial results for these efforts aimed at emittance improvement will also be given in the paper.

  15. Molybdenum evidence for expansive sulfidic water masses in ~ 750 Ma oceans

    DEFF Research Database (Denmark)

    Dahl, Tais Wittchen; Canfield, Donald Eugene; Rosing, Minik Thorleif

    2011-01-01

    composition of ancient seawater. Further, we investigate the ~ 750 Ma Walcott Member of the Chuar Group, Grand Canyon, which accumulated in a rift basin with open connection to the ocean. Iron speciation data from upper Walcott shales indicate that local bottom waters were anoxic and sulfidic, consistent......-Neoproterozoic oceans, bridging a nearly 700 million-year gap in previous Mo data. We propose that anoxic and sulfidic (euxinic) conditions governed Mo cycling in the oceans even as ferruginous subsurface waters re-appeared 800–750 Ma, and we interpret this anoxic ocean state to reflect a markedly lower atmospheric...

  16. Maíz: Alimento fundamental en las tradiciones y costumbres mexicanas

    OpenAIRE

    José de Jesús Cuevas Mejía

    2014-01-01

    El siguiente trabajo busca recalcar la importancia del maíz para el pueblo mexicano, que con el paso de los años ha logrado mantener su identidad no en vano por la fuerza y majestuosidad de sus tradiciones y costumbres. Es cierto que hoy en día es la base de la alimentación de muchas familias a lo largo del territorio de México, en cada hogar a la hora del almuerzo, la comida e incluso la merienda, el maíz está presente en una gran variedad de formas, texturas y colores. Esto nos hace pensar ...

  17. Non-economic determinants of structural transformations in Małopolska agriculture

    Directory of Open Access Journals (Sweden)

    Maciej Basaj

    2009-01-01

    Full Text Available In the article results of the research conducted in 2008 among farmers in two districts located in northern part of the Małopolska voivodeship have been presented. The aim of the article is the presentation of farmers’ opinions and attitudes against accomplishing structural alternations in their vicinity. Getting to know farmers’ intentions against the future of their farms, and also getting to know their estimations about the future of their farms in the vicinity can have particular significance in the prognosis and program of further development of rural areas – especially in such a region, with a big agrarian overpopulation as the Małopolska.

  18. MA- IDS: A Distributed Intrusion Detection System Based on Data Mining

    Institute of Scientific and Technical Information of China (English)

    SUN Jian-hua; JIN Hai; CHEN Hao; HAN Zong-fen

    2005-01-01

    Aiming at the shortcomings in intrusion detection systems (IDSs) used in commercial and research fields,we propose the MA-IDS system, a distributed intrusion detection system based on data mining. In this model, misuse intrusion detection system (MIDS) and anomaly intrusion detection system (AIDS) are combined. Data mining is applied to raise detection performance, and distributed mechanism is employed to increase the scalability and efficiency. Host- and network-based mining algorithms employ an improved Bayesian decision theorem that suits for real security environment to minimize the risks incurred by false decisions. We describe the overall architecture of the MA-IDS system, and discuss specific design and implementation issue.

  19. Chinese enterprise’s wealth effect of cross-border M&A

    Directory of Open Access Journals (Sweden)

    Yang Xingrui

    2016-01-01

    Full Text Available This paper explores the Chinese enterprises’ wealth effect of cross-border M&A and the factors which impact it. The results indicate that in the [-10, 10] event window Chinese enterprises’ get wealth effect from cross-border M&A, but in the longer event windows this wealth effect doesn’t exist. And high R&D density of the acquirer enterprises, acquisitions experience and host country’s high level of innovation have positive influence to this cumulative abnormal return, while large asset scale, high growth speed, high equity centralized degrees and horizontal acquisition mode have significant negative effects.

  20. Creating value in pharma through M&A : the case of Watson Pharmaceuticals

    OpenAIRE

    Zweiphenning, Sebastian Marinus

    2016-01-01

    This paper analyses the motives for mergers and acquisitions (M&A) in the pharmaceutical sector and whether these M&A’s create value. In order to give an industry perspective and let the reader experience the situation wherein managers of pharmaceutical companies operate, a case-study on Watson Pharmaceuticals is done. It provides a detailed perspective into the company’s M&A rationale. Through the literature review as well as the case-study the changes in the pharmaceutical industry are desc...

  1. IA/MA/AMPS 三元共聚物阻垢剂的性能评价%Performance evaluation of IA/MA/AMPS terpolymer scale inhibitor

    Institute of Scientific and Technical Information of China (English)

    张凤华; 刘鹏宇; 李飞

    2016-01-01

    In view of the IA/MA/AMPS terpolymer scale inhibitors.The effect of mass concentration of cal-cium ion,water temperature and pH of medium on the scale inhibition performance for calcium carbonate were investigated.The thermal stability of the copolymer scale inhibitors were analyzed via TG.The com-parison experiments of copolymer scale inhibitor and commercial scale inhibitor were carried on the disper-sion performance of scale inhibitors for ferric oxide.Results show that the ternary copolymer scale inhibitor has good thermal stability.The dispersion performance of scale inhibitors for ferric oxide is superior to com-mercial copolymer scale inhibitors WD-700 and T-225.It is found that copolymer scale inhibitors are suit-able for weak alkaline (pH =7 ~9),high temperature and moderate hardness water system.%针对实验合成的 IA /MA /AMPS 三元共聚物阻垢剂,分别考察了钙离子质量浓度、水样温度、水样 pH 值对共聚物阻垢性能的影响,合成的共聚物与市售阻垢剂分散氧化铁的性能进行了对比实验,并对提纯后的 IA /MA /AMPS 三元共聚物阻垢剂作 TG 分析。结果表明,合成的三元共聚物阻垢剂具有良好的热稳定性,分散氧化铁性能优于市售阻垢剂,适用于弱碱性、高温、中等矿化度的工业循环冷却水。

  2. MaRiMba: a software application for spectral library-based MRM transition list assembly.

    Science.gov (United States)

    Sherwood, Carly A; Eastham, Ashley; Lee, Lik Wee; Peterson, Amelia; Eng, Jimmy K; Shteynberg, David; Mendoza, Luis; Deutsch, Eric W; Risler, Jenni; Tasman, Natalie; Aebersold, Ruedi; Lam, Henry; Martin, Daniel B

    2009-10-01

    Multiple reaction monitoring mass spectrometry (MRM-MS) is a targeted analysis method that has been increasingly viewed as an avenue to explore proteomes with unprecedented sensitivity and throughput. We have developed a software tool, called MaRiMba, to automate the creation of explicitly defined MRM transition lists required to program triple quadrupole mass spectrometers in such analyses. MaRiMba creates MRM transition lists from downloaded or custom-built spectral libraries, restricts output to specified proteins or peptides, and filters based on precursor peptide and product ion properties. MaRiMba can also create MRM lists containing corresponding transitions for isotopically heavy peptides, for which the precursor and product ions are adjusted according to user specifications. This open-source application is operated through a graphical user interface incorporated into the Trans-Proteomic Pipeline, and it outputs the final MRM list to a text file for upload to MS instruments. To illustrate the use of MaRiMba, we used the tool to design and execute an MRM-MS experiment in which we targeted the proteins of a well-defined and previously published standard mixture.

  3. PuMa-II: A wide band pulsar machine for the Westerbork Synthesis Radio Telescope

    NARCIS (Netherlands)

    Karuppusamy, R.; Stappers, B.; van Straten, W.

    2008-01-01

    The Pulsar Machine II (PuMa-II) is the new flexible pulsar processing back-end system at the Westerbork Synthesis Radio Telescope (WSRT), specifically designed to take advantage of the upgraded WSRT. The instrument is based on a computer cluster running the Linux operating system, with minimal custo

  4. 77 FR 40147 - Boston and Maine Corporation-Abandonment Exemption-in Worcester County, MA

    Science.gov (United States)

    2012-07-06

    ... Surface Transportation Board Boston and Maine Corporation--Abandonment Exemption--in Worcester County, MA Boston and Maine Corporation (B&M) has filed a verified notice of exemption under 49 CFR part 1152....\\1\\ The line traverses United States Postal Service Zip Code 01440. \\1\\ On June 20, 2012, the...

  5. 33 CFR 165.113 - Security Zone: Dignitary arrival/departure Logan International Airport, Boston, MA

    Science.gov (United States)

    2010-07-01

    .../departure Logan International Airport, Boston, MA 165.113 Section 165.113 Navigation and Navigable Waters... Guard District § 165.113 Security Zone: Dignitary arrival/departure Logan International Airport, Boston... governments arriving at, or departing from, Logan International Airport and as determined by the transit...

  6. Production and Application of Monoclonal Antibodies Against Methamphetamine (MA) and Morphine (MP)

    Institute of Scientific and Technical Information of China (English)

    2001-01-01

    Three monoclonal antibodies (MAbs) against metharnphetamine (BD1, BD2, BD10) and four MAbs against morphine (MP6A8, MP6D9, MP7D6, MP8D9) are obtained by using MA-conjugated bovine serum albumin (BSA) and MP-conjugated BSA as immunogens, respectively. The MAbs against MA belonged to the IgG1 subclass with λ chains. The association constants (Ka) of the antibodies are higher than 107 L/mol (RIA). The MAbs against MP also belonged to the IgG1 subclass with λ chains. Ka of these antibodies is higher thanThree monoclonal antibodies (MAbs) against metharnphetamine (BD1, BD2, BD10) and four MAbs against morphine (MP6A8, MP6D9, MP7D6, MP8D9) are obtained by using MA-conjugated bovine serum albumin (BSA) and MP-conjugated BSA as immunogens, respectively. The MAbs against MA belonged to the IgG1 subclass with λ chains. The association constants (Ka) of the antibodies are higher than 107 L/mol (RIA). The MAbs against MP also belonged to the IgG1 subclass with λ chains. Ka of these antibodies is higher than 108

  7. Experimental study for 15-20 mA dc H- multicusp sourcea)

    Science.gov (United States)

    Zhang, Tianjue; Jia, Xianlu; Lv, Yinlong; Zou, Jian; Guan, Fengping; Wu, Longcheng; Pan, Gaofeng; Liu, Gengshou; Lin, Jun; Ge, Tao; Yao, Hongjuan; Wang, Zhenhui; An, Shizhong

    2010-02-01

    Recently, a new H- source and test stand was developed at CIAE. The design of this new source is based on the experience on our previous 10-15 mA H- ion source and the source at TRIUMF. Major efforts include the study of the virtual filter magnetic field, confining magnetic field, filament shape and location, the vacuum improvement on the extracting area, the extraction optics, new control and interlock system of the power supplies. More than 15 mA of H-beam was obtained for 36 h with stability of ±0.5%. The normalized emittance of 0.48π mm mrad (4 rms normalized emittance) were measured with ˜8 mA dc beam. Further experimental studies are proceeding in an effort to reach 20 mA with reasonable emittance at this moment. More study plans are conducted, e.g., building a longer source body and using cesium injection to get better emittance, which will be presented as a separate paper at this conference.

  8. Experimental study for 15-20 mA dc H{sup -} multicusp source

    Energy Technology Data Exchange (ETDEWEB)

    Zhang Tianjue; Jia Xianlu; Lv Yinlong; Zou Jian; Guan Fengping; Wu Longcheng; Pan Gaofeng; Liu Gengshou; Lin Jun; Ge Tao; Yao Hongjuan; Wang Zhenhui; An Shizhong [China Institute of Atomic Energy, P.O. Box 275(3), Beijing 102413 (China)

    2010-02-15

    Recently, a new H- source and test stand was developed at CIAE. The design of this new source is based on the experience on our previous 10-15 mA H{sup -} ion source and the source at TRIUMF. Major efforts include the study of the virtual filter magnetic field, confining magnetic field, filament shape and location, the vacuum improvement on the extracting area, the extraction optics, new control and interlock system of the power supplies. More than 15 mA of H-beam was obtained for 36 h with stability of {+-}0.5%. The normalized emittance of 0.48{pi} mm mrad (4 rms normalized emittance) were measured with {approx}8 mA dc beam. Further experimental studies are proceeding in an effort to reach 20 mA with reasonable emittance at this moment. More study plans are conducted, e.g., building a longer source body and using cesium injection to get better emittance, which will be presented as a separate paper at this conference.

  9. Experimental study for 15-20 mA dc H- multicusp source.

    Science.gov (United States)

    Zhang, Tianjue; Jia, Xianlu; Lv, Yinlong; Zou, Jian; Guan, Fengping; Wu, Longcheng; Pan, Gaofeng; Liu, Gengshou; Lin, Jun; Ge, Tao; Yao, Hongjuan; Wang, Zhenhui; An, Shizhong

    2010-02-01

    Recently, a new H- source and test stand was developed at CIAE. The design of this new source is based on the experience on our previous 10-15 mA H(-) ion source and the source at TRIUMF. Major efforts include the study of the virtual filter magnetic field, confining magnetic field, filament shape and location, the vacuum improvement on the extracting area, the extraction optics, new control and interlock system of the power supplies. More than 15 mA of H-beam was obtained for 36 h with stability of +/-0.5%. The normalized emittance of 0.48pi mm mrad (4 rms normalized emittance) were measured with approximately 8 mA dc beam. Further experimental studies are proceeding in an effort to reach 20 mA with reasonable emittance at this moment. More study plans are conducted, e.g., building a longer source body and using cesium injection to get better emittance, which will be presented as a separate paper at this conference.

  10. Isolation and propagation of the animal rotaviruses in MA-104 cells--30 years of practical experience.

    Science.gov (United States)

    Otto, Peter H; Reetz, Jochen; Eichhorn, Werner; Herbst, Werner; Elschner, Mandy C

    2015-10-01

    A total of 136 rotavirus positive samples from diarrhoeic animals of different species were submitted for isolation and cultural propagation of rotavirus on MA-104 cells. The samples were collected from animals with diarrhoea, between 1980 and 2010, originating from herds or farms located in several parts of Germany. Rotaviruses of species A were isolated from 102 faecal samples in cultures of MA-104 cells under the following conditions: pre-treatment of virus with trypsin, incorporation of trypsin into culture medium, use of roller cultures, and centrifugation of the samples on the cells. The cell culture adapted viruses produced a cytopathic effect, accompanied by the release of cells from the glass surface of the cultivation vessels. After 10 passages the virus isolates yielded titres between 10(5.5) and 10(7.5)ml(-1) TCID50. Isolation and serial propagation of the virus in MA-104 cells was confirmed by immunofluorescence assay, transmission electron microscopy, and polyacrylamide-gel electrophoresis of viral dsRNA. Eight (5.9%) of the electrophoretic profiles were characteristic of species B or D rotaviruses, which were not replicated in MA-104 cells.

  11. 42 CFR 422.54 - Continuation of enrollment for MA local plans.

    Science.gov (United States)

    2010-10-01

    ... requirements: (i) Obtain CMS's approval of the continuation area, the marketing materials that describe the.... The enrollee must make the choice of continuing enrollment in a manner specified by CMS. If no choice... which the enrollee no longer resides). (4) Protection of enrollee rights. An MA organization that...

  12. Shijun Ma: keeping on exploring new areas to meet the challenge of human and social demands

    Institute of Scientific and Technical Information of China (English)

    Le Kang; Ming Li

    2011-01-01

    @@ Professor Shijun Ma (1915-1991) is a renowned Chinese ecologist.Shijun, literally in Chinese, means the finest horse,which also perfectly describes his academic lifc 50 years of non-stop traveling and exploring new areas, from insects to human being, from experimental science to systematic science, from ecology to environmental science, and from nature to society.

  13. 75 FR 51938 - Drawbridge Operation Regulation; Taunton River, Fall River and Somerset, MA

    Science.gov (United States)

    2010-08-24

    ... River and Somerset, MA AGENCY: Coast Guard, DHS. ACTION: Final rule. SUMMARY: The Coast Guard has...) Bridge at mile 1.8, across the Taunton River between Fall River and Somerset, Massachusetts. This final..., across the Taunton River between Fall River and Somerset, Massachusetts, has a vertical clearance in...

  14. 75 FR 32351 - Drawbridge Operation Regulation; Taunton River, Fall River and Somerset, MA

    Science.gov (United States)

    2010-06-08

    ... River and Somerset, MA AGENCY: Coast Guard, DHS. ACTION: Notice of proposed rulemaking. SUMMARY: The...) Bridge at mile 1.8, between Fall River and Somerset, Massachusetts, to help relieve the bridge owner from... Taunton River between Fall River and Somerset, Massachusetts, has a vertical clearance in the...

  15. Chronic N-amended soils exhibit an altered bacterial community structure in Harvard Forest, MA, USA

    Science.gov (United States)

    Swathi A. Turlapati; Rakesh Minocha; Premsai S. Bhiravarasa; Louise S. Tisa; William K. Thomas; Subhash C. Minocha

    2013-01-01

    At the Harvard Forest, Petersham, MA, the impact of 20 years of annual ammonium nitrate application to the mixed hardwood stand on soil bacterial communities was studied using 16S rRNA genes pyrosequencing. Amplification of 16S rRNA genes was done using DNA extracted from 30 soil samples (three treatments x two horizons x five subplots) collected from untreated (...

  16. "ma ei kirjuta vastikuid ridu..." : [luuletused] / [Viiding, Juhan] Jüri Üdi

    Index Scriptorium Estoniae

    Üdi, Jüri, pseud., 1948-1995

    1998-01-01

    "ma ei kirjuta vastikuid ridu..." ; "memm kinkis mulle karabiini..." ; "kord kasutütar hülgas omakasu..." ; Krauklis ; Tee ; klaperjaht ; "miks sina rääkides longid..." ; Suveteater ; "tematemaatikatematemaatika..." ; "see ilmaliku pihi..." ; "on tahtmine taevariik..." ; Pidulikeks juhtudeks : autoportree selgituseks ; dialoog doktoriga ; rahatuvi ; ha-ha-ha-ha (couplet) ; kunstniku kool ; Loetelu ; Lahkumised ; Teade Christian Morgensternile ; Kiri vendadele ; Lihtne luuletus ; "üks korralik pere ei taha..." ; Tagala ; Latern ; Peapõrutus ; "Sel poisil oli raske veretõbi..." ; "alles elavate kadunute kirju..." ; Imede ime ; Kõned sisemaal ; "Me teeme, teeme ümber oma elu..." ; Avatud laul ; "Kaks ühekäelist meest on tule ääres..." ; ""Aeglast enesetappu ei anna..." ; "Mis on see luuletaja luule..." ; "Ma kuklas tunnen eluaegset kuuli..." ; Vaikelu ; 1954 ; "Kui matate, siis ärge enam pooge..." ; Eluküsimus ; "1954..." ; "Ta istub..." ; "Nii imelik, mu noorusel on sõnad..." ; "Tuleb ette vaevalisi tunde..." ; "Ma olen pannud segast..." ; "Mida ma tahtsingi öelda..." ; "Kõik läheb omasoodu..."

  17. Positive and Negative Impacts of Cross-border M&A

    Institute of Scientific and Technical Information of China (English)

    裴长洪; 林江

    2007-01-01

    Mergers and acquisitions of Chinese enterprises by foreign investors have moved onto the public radar in recent years.To date,the M&A frenzy has drawn widespread attention,with a mixed reaction from proponents and opponents.Proponents consider such mergers and acquisitions conducive to realizing strategic readjustment of the national economic structure,optimizing resource allocation and improving the corporate governance structure.Opponents,however,are concerned that foreign mergers and acquisitions may jeopardize China’s industrial security and erode the executive power of the central government in undertaking industrial development planning.Are the benefits of M&A outweighed by the costs,or vice versa? The focus column of this edition features two articles which debate this issue from opposing viewpoints.In the article"Positive and Negative Impacts of Cross-border M&A",the authors consider foreign M(?)A to be a new way of boosting the level of foreign investment utilization,and advocate China taking full advantage of this approach.The authors of the article"Self-Improvement Or Self-Mutilation",meanwhile,hold foreign M&A to blame for state-owned asset erosion,and insist that China should oppose mergers and acquisitions of key state- owned enterprises by foreign investors at fire-sale prices.

  18. redMaGiC: selecting luminous red galaxies from the DES Science Verification data

    Science.gov (United States)

    Rozo, E.; Rykoff, E. S.; Abate, A.; Bonnett, C.; Crocce, M.; Davis, C.; Hoyle, B.; Leistedt, B.; Peiris, H. V.; Wechsler, R. H.; Abbott, T.; Abdalla, F. B.; Banerji, M.; Bauer, A. H.; Benoit-Lévy, A.; Bernstein, G. M.; Bertin, E.; Brooks, D.; Buckley-Geer, E.; Burke, D. L.; Capozzi, D.; Rosell, A. Carnero; Carollo, D.; Kind, M. Carrasco; Carretero, J.; Castander, F. J.; Childress, M. J.; Cunha, C. E.; D'Andrea, C. B.; Davis, T.; DePoy, D. L.; Desai, S.; Diehl, H. T.; Dietrich, J. P.; Doel, P.; Eifler, T. F.; Evrard, A. E.; Neto, A. Fausti; Flaugher, B.; Fosalba, P.; Frieman, J.; Gaztanaga, E.; Gerdes, D. W.; Glazebrook, K.; Gruen, D.; Gruendl, R. A.; Honscheid, K.; James, D. J.; Jarvis, M.; Kim, A. G.; Kuehn, K.; Kuropatkin, N.; Lahav, O.; Lidman, C.; Lima, M.; Maia, M. A. G.; March, M.; Martini, P.; Melchior, P.; Miller, C. J.; Miquel, R.; Mohr, J. J.; Nichol, R. C.; Nord, B.; O'Neill, C. R.; Ogando, R.; Plazas, A. A.; Romer, A. K.; Roodman, A.; Sako, M.; Sanchez, E.; Santiago, B.; Schubnell, M.; Sevilla-Noarbe, I.; Smith, R. C.; Soares-Santos, M.; Sobreira, F.; Suchyta, E.; Swanson, M. E. C.; Thaler, J.; Thomas, D.; Uddin, S.; Vikram, V.; Walker, A. R.; Wester, W.; Zhang, Y.; da Costa, L. N.

    2016-09-01

    We introduce redMaGiC, an automated algorithm for selecting luminous red galaxies (LRGs). The algorithm was specifically developed to minimize photometric redshift uncertainties in photometric large-scale structure studies. redMaGiC achieves this by self-training the colour cuts necessary to produce a luminosity-thresholded LRG sample of constant comoving density. We demonstrate that redMaGiC photo-zs are very nearly as accurate as the best machine learning-based methods, yet they require minimal spectroscopic training, do not suffer from extrapolation biases, and are very nearly Gaussian. We apply our algorithm to Dark Energy Survey (DES) Science Verification (SV) data to produce a redMaGiC catalogue sampling the redshift range z ∈ [0.2, 0.8]. Our fiducial sample has a comoving space density of 10-3 (h-1 Mpc)-3, and a median photo-z bias (zspec - zphoto) and scatter (σz/(1 + z)) of 0.005 and 0.017, respectively. The corresponding 5σ outlier fraction is 1.4 per cent. We also test our algorithm with Sloan Digital Sky Survey Data Release 8 and Stripe 82 data, and discuss how spectroscopic training can be used to control photo-z biases at the 0.1 per cent level.

  19. redMaGiC: Selecting Luminous Red Galaxies from the DES Science Verification Data

    CERN Document Server

    Rozo, E; Abate, A; Bonnett, C; Crocce, M; Davis, C; Hoyle, B; Leistedt, B; Peiris, H V; Wechsler, R H; Abbott, T; Abdalla, F B; Banerji, M; Bauer, A H; Benoit-Lévy, A; Bernstein, G M; Bertin, E; Brooks, D; Buckley-Geer, E; Burke, D L; Capozzi, D; Rosell, A Carnero; Carollo, D; Kind, M Carrasco; Carretero, J; Castander, F J; Childress, M J; Cunha, C E; D'Andrea, C B; Davis, T; DePoy, D L; Desai, S; Diehl, H T; Dietrich, J P; Doel, P; Eifler, T F; Evrard, A E; Neto, A Fausti; Flaugher, B; Fosalba, P; Frieman, J; Gaztanaga, E; Gerdes, D W; Glazebrook, K; Gruen, D; Gruendl, R A; Honscheid, K; James, D J; Jarvis, M; Kim, A G; Kuehn, K; Kuropatkin, N; Lahav, O; Lidman, C; Lima, M; Maia, M A G; March, M; Martini, P; Melchior, P; Miller, C J; Miquel, R; Mohr, J J; Nichol, R C; Nord, B; O'Neill, C R; Ogando, R; Plazas, A A; Romer, A K; Roodman, A; Sako, M; Sanchez, E; Santiago, B; Schubnell, M; Sevilla-Noarbe, I; Smith, R C; Soares-Santos, M; Sobreira, F; Suchyta, E; Swanson, M E C; Thaler, J; Thomas, D; Uddin, S; Vikram, V; Walker, A R; Wester, W; Zhang, Y; da Costa, L N

    2015-01-01

    We introduce redMaGiC, an automated algorithm for selecting Luminous Red Galaxies (LRGs). The algorithm was specifically developed to minimize photometric redshift uncertainties in photometric large-scale structure studies. redMaGiC achieves this by self-training the color-cuts necessary to produce a luminosity-thresholded LRG sample of constant comoving density. We demonstrate that redMaGiC photozs are very nearly as accurate as the best machine-learning based methods, yet they require minimal spectroscopic training, do not suffer from extrapolation biases, and are very nearly Gaussian. We apply our algorithm to Dark Energy Survey (DES) Science Verification (SV) data to produce a redMaGiC catalog sampling the redshift range $z\\in[0.2,0.8]$. Our fiducial sample has a comoving space density of $10^{-3}\\ (h^{-1} Mpc)^{-3}$, and a median photoz bias ($z_{spec}-z_{photo}$) and scatter $(\\sigma_z/(1+z))$ of 0.005 and 0.017 respectively. The corresponding $5\\sigma$ outlier fraction is 1.4%. We also test our algorit...

  20. Functional Equivalence of Retroviral MA Domains in Facilitating Psi RNA Binding Specificity by Gag

    Directory of Open Access Journals (Sweden)

    Tiffiny Rye-McCurdy

    2016-09-01

    Full Text Available Retroviruses specifically package full-length, dimeric genomic RNA (gRNA even in the presence of a vast excess of cellular RNA. The “psi” (Ψ element within the 5′-untranslated region (5′UTR of gRNA is critical for packaging through interaction with the nucleocapsid (NC domain of Gag. However, in vitro Gag binding affinity for Ψ versus non-Ψ RNAs is not significantly different. Previous salt-titration binding assays revealed that human immunodeficiency virus type 1 (HIV-1 Gag bound to Ψ RNA with high specificity and relatively few charge interactions, whereas binding to non-Ψ RNA was less specific and involved more electrostatic interactions. The NC domain was critical for specific Ψ binding, but surprisingly, a Gag mutant lacking the matrix (MA domain was less effective at discriminating Ψ from non-Ψ RNA. We now find that Rous sarcoma virus (RSV Gag also effectively discriminates RSV Ψ from non-Ψ RNA in a MA-dependent manner. Interestingly, Gag chimeras, wherein the HIV-1 and RSV MA domains were swapped, maintained high binding specificity to cognate Ψ RNAs. Using Ψ RNA mutant constructs, determinants responsible for promoting high Gag binding specificity were identified in both systems. Taken together, these studies reveal the functional equivalence of HIV-1 and RSV MA domains in facilitating Ψ RNA selectivity by Gag, as well as Ψ elements that promote this selectivity.

  1. Evidence for a previously unrecognized mycobacterial endosymbiont in Acanthamoeba castellanii strain Ma (ATCC ® 50370 ™).

    Science.gov (United States)

    Glaser, Kathleen C; Hetrick, Neil D; Molestina, Robert E

    2011-01-01

    We describe the isolation of a mycobacterium from Acanthamoeba castellanii strain Ma (ATCC(®) 50370(™)). The mycobacterium resides within vacuoles of A. castellanii, can be cultured by routine methodologies, and is a member of the Mycobacterium avium complex. Previously unrecognized mycobacterial endosymbionts are likely common among strains of Acanthamoeba housed at culture collections.

  2. Cold Gas in Quenched Dwarf Galaxies using HI-MaNGA

    Science.gov (United States)

    Bonilla, Alaina

    2017-01-01

    MaNGA (Mapping of Nearby Galaxies at Apache Point Observatory) is a 6-year Sloan Digital Sky Survey fourth generation (SDSS-IV) project that will obtain integral field spectroscopy of a catalogue of 10,000 nearby galaxies. In this study, we explore the properties of the passive dwarf galaxy sample presented in Penny et al. 2016, making use of MaNGA IFU (Integral Field Unit) data to plot gas emission, stellar velocity, and flux maps. In addition, HI-MaNGA, a legacy radio-survey of MaNGA, collects single dish HI data retrieved from the GBT (Green Bank Telescope), which we use to study the the 21cm emission lines present in HI detections. Studying the HI content of passive dwarves will help us reveal the processes that are preventing star formation, such as possible AGN feedback. This work was supported by the SDSS Research Experience for Undergraduates program, which is funded by a grant from the Sloan Foundation to the Astrophysical Research Consortium.

  3. Fabrication Technological Development of the Oxide Dispersion Strengthened Alloy MA957 for Fast Reactor Applications

    Energy Technology Data Exchange (ETDEWEB)

    Hamilton, Margaret L.; Gelles, David S.; Lobsinger, Ralph J.; Johnson, Gerald D.; Brown, W. F.; Paxton, Michael M.; Puigh, Raymond J.; Eiholzer, Cheryl R.; Martinez, C.; Blotter, M. A.

    2000-02-28

    A significant amount of effort has been devoted to determining the properties and understanding the behavior of the alloy MA957 to define its potential usefulness as a cladding material in the fast breeder reactor program. The numerous characterization and fabrication studies that were conducted are documented in this report.

  4. 77 FR 29251 - Safety Zone; Carnival Fireworks Display, Nantasket Beach, Hull, MA

    Science.gov (United States)

    2012-05-17

    ... SECURITY Coast Guard 33 CFR Part 165 RIN 1625-AA00 Safety Zone; Carnival Fireworks Display, Nantasket Beach... vicinity of Hull, MA for a Carnival fireworks display. This temporary safety zone is necessary to protect... Youth Football is sponsoring a Carnival fireworks display on the waters off of Nantasket Beach in the...

  5. Was there a super-eruption on the Gondwanan coast 477 Ma ago?

    Science.gov (United States)

    Gutiérrez-Alonso, G.; Gutiérrez-Marco, J. C.; Fernández-Suárez, J.; Bernárdez, E.; Corfu, F.

    2016-06-01

    Precise zircon and monazite ID-TIMS U-Pb dating of three Lower Ordovician altered ash-fall tuff beds (K-bentonites) in the Cantabrian Zone of NW Iberia yielded coeval ages together with an equivalent previously studied sample (477.5 ± 1 (Gutierrez-Alonso et al., 2007)), of 477 ± 1.3 Ma, 477.2 ± 1.1 Ma and 477.3 ± 1 Ma, with a pooled concordia age (all analyses in the four samples) of 477.2 ± 0.74 Ma. A conservative estimation of the volume and mass of the studied K-bentonite beds (using exclusively the CZ data) yields a volume for the preserved deposits of ca. 37.5 km3 (Volcanic Explosivity Index - VEI = 6, Colossal). When considering other putative equivalent beds in Iberia and neighboring realms (i.e. Armorica, Sardinia) the volume of ejecta associated to this event would make it reach the Supervolcanic-Apocalyptic status (VEI = 8, > 1000 km3). At variance with most known cases of this kind of gigantic eruption events, geological observations indicate that the studied magmatic event was related to continental margin extension and thinning and not to plate convergence. We speculate that a geochronologically equivalent large caldera event recognized in the geological record of NW Iberia could be ground zero of this super-eruption.

  6. 77 FR 34797 - Drawbridge Operation Regulations; Chelsea River, Chelsea and East Boston, MA

    Science.gov (United States)

    2012-06-12

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF HOMELAND SECURITY Coast Guard 33 CFR Part 117 Drawbridge Operation Regulations; Chelsea River, Chelsea and East Boston, MA AGENCY: Coast Guard, DHS. ACTION: Notice of temporary deviation from regulations. SUMMARY:...

  7. 76 FR 14804 - Drawbridge Operation Regulations; Annisquam River and Blynman Canal, Gloucester, MA

    Science.gov (United States)

    2011-03-18

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF HOMELAND SECURITY Coast Guard 33 CFR Part 117 Drawbridge Operation Regulations; Annisquam River and Blynman Canal, Gloucester, MA AGENCY: Coast Guard, DHS. ACTION: Notice of temporary deviation from regulations. SUMMARY:...

  8. 78 FR 18849 - Drawbridge Operation Regulations; Saugus River, Saugus and Lynn, MA

    Science.gov (United States)

    2013-03-28

    ... From the Federal Register Online via the Government Publishing Office ] DEPARTMENT OF HOMELAND SECURITY Coast Guard 33 CFR Part 117 Drawbridge Operation Regulations; Saugus River, Saugus and Lynn, MA AGENCY: Coast Guard, DHS. ACTION: Notice of temporary deviation from regulations. SUMMARY: The...

  9. 78 FR 65874 - Drawbridge Operation Regulations; Mystic River, Charlestown and Everett, MA

    Science.gov (United States)

    2013-11-04

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF HOMELAND SECURITY Coast Guard 33 CFR Part 117 Drawbridge Operation Regulations; Mystic River, Charlestown and Everett, MA AGENCY: Coast Guard, DHS. ACTION: Notice of temporary deviation from regulations. SUMMARY:...

  10. 77 FR 56115 - Drawbridge Operation Regulations; Fort Point Channel, Boston, MA

    Science.gov (United States)

    2012-09-12

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF HOMELAND SECURITY Coast Guard 33 CFR Part 117 Drawbridge Operation Regulations; Fort Point Channel, Boston, MA AGENCY: Coast Guard, DHS. ACTION: Notice of temporary deviation from regulations. SUMMARY: The...

  11. 76 FR 3516 - Drawbridge Operation Regulations; Merrimack River, Newburyport and Salisbury, MA

    Science.gov (United States)

    2011-01-20

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF HOMELAND SECURITY Coast Guard 33 CFR Part 117 Drawbridge Operation Regulations; Merrimack River, Newburyport and Salisbury, MA AGENCY: Coast Guard, DHS. ACTION: Notice of temporary deviation from regulations. SUMMARY:...

  12. 78 FR 11747 - Drawbridge Operation Regulations; Chelsea River, Chelsea and East Boston, MA

    Science.gov (United States)

    2013-02-20

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF HOMELAND SECURITY Coast Guard 33 CFR Part 117 Drawbridge Operation Regulations; Chelsea River, Chelsea and East Boston, MA AGENCY: Coast Guard, DHS. ACTION: Notice of temporary deviation from regulation. SUMMARY:...

  13. 77 FR 37317 - Drawbridge Operation Regulations; Merrimack River, Haverhill and West Newbury, MA

    Science.gov (United States)

    2012-06-21

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF HOMELAND SECURITY Coast Guard 33 CFR Part 117 Drawbridge Operation Regulations; Merrimack River, Haverhill and West Newbury, MA AGENCY: Coast Guard, DHS. ACTION: Notice of temporary deviation from regulations. SUMMARY:...

  14. 76 FR 79065 - Drawbridge Operation Regulations; Annisquam River and Blynman Canal, Gloucester, MA

    Science.gov (United States)

    2011-12-21

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF HOMELAND SECURITY Coast Guard 33 CFR Part 117 Drawbridge Operation Regulations; Annisquam River and Blynman Canal, Gloucester, MA AGENCY: Coast Guard, DHS. ACTION: Notice of temporary deviation from regulations. SUMMARY:...

  15. 76 FR 4817 - Drawbridge Operation Regulations; Chelsea River, Chelsea and East Boston, MA

    Science.gov (United States)

    2011-01-27

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF HOMELAND SECURITY Coast Guard 33 CFR Part 117 Drawbridge Operation Regulations; Chelsea River, Chelsea and East Boston, MA AGENCY: Coast Guard, DHS. ACTION: Notice of temporary deviation from regulations. SUMMARY:...

  16. 77 FR 42433 - Drawbridge Operation Regulations; Saugus River, Lynn and Revere, MA

    Science.gov (United States)

    2012-07-19

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF HOMELAND SECURITY Coast Guard 33 CFR Part 117 Drawbridge Operation Regulations; Saugus River, Lynn and Revere, MA AGENCY: Coast Guard, DHS. ACTION: Notice of temporary deviation from regulations. SUMMARY: The...

  17. The retrovirus MA and PreTM proteins follow immature MVL cores

    DEFF Research Database (Denmark)

    Andersen, Klaus Bahl

    2013-01-01

    Detergent can dissolve retrovirus, exept the immature core. Here we show that the Matrix protein (MA) and the Transmembrane protein in its immature form (PreTM) bind to the retrovirus core. These attachments explain the attachment in the virus particle and the dynamics of the ability to fuse...

  18. 76 FR 73510 - Drawbridge Operation Regulations; Saugus River, Lynn and Revere, MA

    Science.gov (United States)

    2011-11-29

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF HOMELAND SECURITY Coast Guard 33 CFR Part 117 Drawbridge Operation Regulations; Saugus River, Lynn and Revere, MA AGENCY: Coast Guard, DHS. ACTION: Notice of temporary deviation from regulations. SUMMARY: The...

  19. 76 FR 32313 - Safety Zone; Chelsea St. Bridge Demolition, Chelsea River, Chelsea, MA

    Science.gov (United States)

    2011-06-06

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF HOMELAND SECURITY Coast Guard 33 CFR Part 165 RIN 1625-AA00 Safety Zone; Chelsea St. Bridge Demolition, Chelsea River, Chelsea, MA AGENCY: Coast Guard, DHS. ACTION: Temporary final rule. SUMMARY: The Coast Guard...

  20. 78 FR 29646 - Drawbridge Operation Regulations; Merrimack River, Haverhill and West Newbury, MA

    Science.gov (United States)

    2013-05-21

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF HOMELAND SECURITY Coast Guard 33 CFR Part 117 Drawbridge Operation Regulations; Merrimack River, Haverhill and West Newbury, MA AGENCY: Coast Guard, DHS. ACTION: Notice of temporary deviation from regulations. SUMMARY:...

  1. 78 FR 9588 - Drawbridge Operation Regulations; Saugus River, Lynn and Revere, MA

    Science.gov (United States)

    2013-02-11

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF HOMELAND SECURITY Coast Guard 33 CFR Part 117 Drawbridge Operation Regulations; Saugus River, Lynn and Revere, MA AGENCY: Coast Guard, DHS. ACTION: Notice of temporary deviation from regulation. SUMMARY: The U.S....

  2. China's first large-scale MA production unit operational in Shanxi

    Institute of Scientific and Technical Information of China (English)

    2008-01-01

    @@ Abrainchild of researchers of the CAS Institute of Coal Chemistry, a production unit capable of turning out 20,000 tons of maleic anhydride (MA) per year, the largest of its kind in China, has come into operation recently at the Shanxi Regent Taiming Chemical Co Ltd in Taiyuan, capital of north China's Shanxi Province.

  3. New compact hohlraum configuration research at the 1.7 MA Z-pinch generator

    Energy Technology Data Exchange (ETDEWEB)

    Kantsyrev, V. L., E-mail: victor@unr.edu; Shrestha, I. K.; Esaulov, A. A.; Safronova, A. S.; Shlyaptseva, V. V.; Osborne, G. C.; Astanovitsky, A. L.; Weller, M. E.; Stafford, A.; Schultz, K. A.; Cooper, M. C. [Physics Department, University of Nevada, Reno, NV 89557 (United States); Chuvatin, A. S. [Laboratorie de Physique des Plasmas, Ecole Polytechnique, 91128 Palaiseau (France); Rudakov, L. I. [Icarus Research Inc., P.O. Box 30780, Bethesda, MD 20824-0780 (United States); Velikovich, A. L. [Plasma Physics Division, Naval Research Laboratory, Washington, DC 20375 (United States); Cuneo, M. E.; Jones, B.; Vesey, R. A. [Sandia National Laboratories, Albuquerque, NM 87110 (United States)

    2014-12-15

    A new compact Z-pinch x-ray hohlraum design with parallel-driven x-ray sources was experimentally demonstrated in a full configuration with a central target and tailored shine shields (to provide a symmetric temperature distribution on the target) at the 1.7 MA Zebra generator. This presentation reports on the joint success of two independent lines of research. One of these was the development of new sources – planar wire arrays (PWAs). PWAs turned out to be a prolific radiator. Another success was the drastic improvement in energy efficiency of pulsed-power systems, such as the Load Current Multiplier (LCM). The Zebra/LCM generator almost doubled the plasma load current to 1.7 MA. The two above-mentioned innovative approaches were used in combination to produce a new compact hohlraum design for ICF, as jointly proposed by SNL and UNR. Good agreement between simulated and measured radiation temperature of the central target is shown. Experimental comparison of PWAs with planar foil liners (PFL) - another viable alternative to wire array loads at multi-MA generators show promising data. Results of research at the University of Nevada Reno allowed for the study of hohlraum coupling physics at University-scale generators. The advantages of new hohlraum design applications for multi-MA facilities with W or Au double PWAs or PFL x-ray sources are discussed.

  4. Asymmetries in conditional mean and variance: Modelling stock returns by asMA-asQGARCH

    NARCIS (Netherlands)

    Brännäs, K.; de Gooijer, J.G.

    2000-01-01

    The asymmetric moving average model (asMA) is extended to allow for asymmetric quadratic conditional heteroskedasticity (asQGARCH). The asymmetric parametrization of the condi- tional variance encompasses the quadratic GARCH model of Sentana (1995). We introduce a framework for testing asymmetries i

  5. Gun Carrying by High School Students in Boston, MA: Does Overestimation of Peer Gun Carrying Matter?

    Science.gov (United States)

    Hemenway, David; Vriniotis, Mary; Johnson, Renee M.; Miller, Matthew; Azrael, Deborah

    2011-01-01

    This paper investigates: (1) whether high school students overestimate gun carrying by their peers, and (2) whether those students who overestimate peer gun carrying are more likely to carry firearms. Data come from a randomly sampled survey conducted in 2008 of over 1700 high school students in Boston, MA. Over 5% of students reported carrying a…

  6. Oh oleksin ma rikas! : [luuletused] / Hans Christian Andersen ; tlk. Harald Rajamets

    Index Scriptorium Estoniae

    Andersen, Hans Christian, 1805-1875

    2004-01-01

    Sisu: Oh oleksin ma rikas! ; Tädi prillid ; "Oh vägev surm, sa külvad tummalt õudu..." ; "Meil maa peal elu kurblik näib..." ; "Kõik kaob nagu tuul siin ära..." ; "Lund on veel maas ja vahel teeb tuisku..."

  7. redMaGiC: selecting luminous red galaxies from the DES Science Verification data

    Energy Technology Data Exchange (ETDEWEB)

    Rozo, E. [Univ. of Arizona, Tucson, AZ (United States). et al.

    2016-05-30

    We introduce redMaGiC, an automated algorithm for selecting Luminous Red Galaxies (LRGs). The algorithm was developed to minimize photometric redshift uncertainties in photometric large-scale structure studies. redMaGiC achieves this by self-training the color-cuts necessary to produce a luminosity-thresholded LRG sam- ple of constant comoving density. Additionally, we demonstrate that redMaGiC photo-zs are very nearly as accurate as the best machine-learning based methods, yet they require minimal spectroscopic training, do not suffer from extrapolation biases, and are very nearly Gaussian. We apply our algorithm to Dark Energy Survey (DES) Science Verification (SV) data to produce a redMaGiC catalog sampling the redshift range z ϵ [0.2,0.8]. Our fiducial sample has a comoving space density of 10-3 (h-1Mpc)-3, and a median photo-z bias (zspec zphoto) and scatter (σz=(1 + z)) of 0.005 and 0.017 respectively.The corresponding 5σ outlier fraction is 1.4%. We also test our algorithm with Sloan Digital Sky Survey (SDSS) Data Release 8 (DR8) and Stripe 82 data, and discuss how spectroscopic training can be used to control photo-z biases at the 0.1% level.

  8. Ma-Xu quantization rule and exact JWKB condition for translationally shape invariant potentials

    Energy Technology Data Exchange (ETDEWEB)

    Grandati, Y. [Institut de Physique, ICPMB, IF CNRS 2843, Universite Paul Verlaine, 1 Bd Arago, 57078 Metz, Cedex 3 (France); Berard, A., E-mail: aberard001@noos.f [Institut de Physique, ICPMB, IF CNRS 2843, Universite Paul Verlaine, 1 Bd Arago, 57078 Metz, Cedex 3 (France)

    2011-01-17

    For translationally shape invariant potentials, the exact quantization rule proposed by Ma and Xu results from the exactness of the modified JWKB quantization condition proved by Barclay. We propose here a very direct alternative way to calculate the appropriate correction for the whole class of translationally shape invariant potentials.

  9. The Data Reduction Pipeline for the SDSS-IV MaNGA IFU Galaxy Survey

    CERN Document Server

    Law, David R; Yan, Renbin; Andrews, Brett H; Bershady, Matthew A; Bizyaev, Dmitry; Blanc, Guillermo A; Blanton, Michael R; Bolton, Adam S; Brownstein, Joel R; Bundy, Kevin; Chen, Yanmei; Drory, Niv; D'Souza, Richard; Fu, Hai; Jones, Amy; Kauffmann, Guinevere; MacDonald, Nicholas; Masters, Karen L; Newman, Jeffrey A; Parejko, John K; Sánchez-Gallego, José R; Sánchez, Sebastian F; Schlegel, David J; Thomas, Daniel; Wake, David A; Weijmans, Anne-Marie; Westfall, Kyle B; Zhang, Kai

    2016-01-01

    Mapping Nearby Galaxies at Apache Point Observatory (MaNGA) is an optical fiber-bundle integral-field unit (IFU) spectroscopic survey that is one of three core programs in the fourth-generation Sloan Digital Sky Survey (SDSS-IV). With a spectral coverage of 3622 - 10,354 Angstroms and an average footprint of ~ 500 arcsec^2 per IFU the scientific data products derived from MaNGA will permit exploration of the internal structure of a statistically large sample of 10,000 low redshift galaxies in unprecedented detail. Comprising 174 individually pluggable science and calibration IFUs with a near-constant data stream, MaNGA is expected to obtain ~ 100 million raw-frame spectra and ~ 10 million reduced galaxy spectra over the six-year lifetime of the survey. In this contribution, we describe the MaNGA Data Reduction Pipeline (DRP) algorithms and centralized metadata framework that produces sky-subtracted, spectrophotometrically calibrated spectra and rectified 3-D data cubes that combine individual dithered observa...

  10. [Usāma ibn Munqidh. Õpetlike näidete raamat

    Index Scriptorium Estoniae

    2016-01-01

    Tutvustus: Usāma ibn Munqidh. Õpetlike näidete raamat : Araabia rüütli mälestused / araabia k. tõlkinud ja kommenteerinud Üllar Peterson. Tallinn : Tallinna Ülikooli Kirjastus, 2015. (Bibliotheca Asiatica)

  11. Expression of MaMAPK Gene in Seedlings of Malus L. under Water Stress

    Institute of Scientific and Technical Information of China (English)

    Li-Xin PENG; Ling-Kun GU; Cheng-Chao ZHENG; De-Quan LI; Huai-Rui SHU

    2006-01-01

    Seedlings of three species of Malus were used to study the expression of mitogen-activated protein kinase (MAPK) in response to water stress: Malus hupehensis, a drought-sensitive species; Malus sieversii, a drought-tolerant species; and Malus micromalus, a middle type. Results showed that Malus MAPK (MaMAPK, GenBank accession No. AF435805) was expressed in both roots and leaves of seedlings of the three Malus species treated with 20% polyethylene glycol for different time periods. Expression levels peaked at 1.5 h after treatment with polyethylene glycol, then decreased to their lowest levels. Liquid kinase assays indicated that the dynamic changes of MAPK activity were very similar to those of the relative expression of MaMAPK mRNA. However, the peak of the former occurred slightly behind the latter. It was noticed that, although the kinase activity decreased after the peak, it was still higher than that of the control during the whole time period. These results suggested that MaMAPK was regulated not only by water stress at the transcription level, but also by phosphorylation and dephosphorylation at the protein level. In addition,of these three apple species, the highest MAPK activity and MaMAPK expression level was found in M.sieversii, followed by M. micromalus and M. hupehensis, suggesting that MAPK might be correlated with drought tolerance in these three species. The different expression levels might be one of the molecular mechanisms of the different drought tolerances in Malus.

  12. Gun Carrying by High School Students in Boston, MA: Does Overestimation of Peer Gun Carrying Matter?

    Science.gov (United States)

    Hemenway, David; Vriniotis, Mary; Johnson, Renee M.; Miller, Matthew; Azrael, Deborah

    2011-01-01

    This paper investigates: (1) whether high school students overestimate gun carrying by their peers, and (2) whether those students who overestimate peer gun carrying are more likely to carry firearms. Data come from a randomly sampled survey conducted in 2008 of over 1700 high school students in Boston, MA. Over 5% of students reported carrying a…

  13. 21 CFR 872.3500 - Polyvinylmethylether maleic anhydride (PVM-MA), acid copolymer, and carboxymethylcellulose sodium...

    Science.gov (United States)

    2010-04-01

    ...), acid copolymer, and carboxymethylcellulose sodium (NACMC) denture adhesive. 872.3500 Section 872.3500...) MEDICAL DEVICES DENTAL DEVICES Prosthetic Devices § 872.3500 Polyvinylmethylether maleic anhydride (PVM-MA), acid copolymer, and carboxymethylcellulose sodium (NACMC) denture adhesive. (a) Identification...

  14. An Introspection for the Field of IS Integration Challenges in M&A

    DEFF Research Database (Denmark)

    Toppenberg, Gustav; Henningsson, Stefan

    2013-01-01

    The last decade has seen a rise in research on the topic of challenges associated with information systems (IS) in corporate mergers and acquisitions (M&As). Although this proliferation of research has the potential to significantly improve our understanding of IS challenges in M&A activity, absent...

  15. 42 CFR 422.62 - Election of coverage under an MA plan.

    Science.gov (United States)

    2010-10-01

    ... disruptive behavior. (3) The individual demonstrates to CMS, in accordance with guidelines issued by CMS... offered by an MA organization and change his or her election, in the form and manner specified by CMS...: (1) CMS or the organization has terminated the organization's contract for the plan, discontinued...

  16. Direct and airborne contact dermatitis in a beekeeper from the Małopolska region.

    Science.gov (United States)

    Basista, Katarzyna

    2012-09-01

    The paper describes an atypical case of simultaneous airborne and direct contact dermatitis in a beekeeper from the Małopolska region. This is the third such case described in a beekeeper in the world and the first in Poland. I suggest that propolis should be regarded as both a direct and airborne contact allergen in beekeepers.

  17. 78 FR 73581 - Massachusetts Disaster #MA-00057 Declaration of Economic Injury

    Science.gov (United States)

    2013-12-06

    ... ADMINISTRATION Massachusetts Disaster MA-00057 Declaration of Economic Injury AGENCY: U.S. Small Business Administration. ACTION: Notice. SUMMARY: This is a notice of an Economic Injury Disaster Loan (EIDL) declaration for the Commonwealth of Massachusetts, dated 11/26/2013. Incident: Russell Street Fire....

  18. COMPARISON OF HEDGES IN M.A. THESES AND PH.D. DISSERTATIONS IN ELT

    Directory of Open Access Journals (Sweden)

    Çağla ATMACA

    2016-08-01

    Full Text Available Writers use some textual devices like hedges and boosters in order to contribute to their textual voice. Differences between M.A. theses and Ph.D. dissertations in English Language Teaching (ELT Department in terms of hedges in Turkish context seem to be an overlooked area. Thus, this paper aims to find the similarities and differences between M.A. theses and Ph.D. dissertations about English Language Teaching in terms of hedges. For this purpose, 10 M.A. theses and 10 Ph.D. dissertations were randomly chosen. Data were analyzed and categorized on the basis of contextual features with the help of content analysis. Various hedging tools emerged as a result of content analysis and it was found that hedges used in the Ph.D. dissertations nearly double those in the M.A. theses. Moreover, modals -followed by passivization- are the leading form of hedging while nouns have the least frequency of hedging type, which could explain some of the differences between novice and experienced writers. In the light of these findings, important implications are drawn for graduate and postgraduate students to enhance their writing skills and be familiar with the principles of academic writing for their future career.

  19. Data of evolutionary structure change: 1DSUA-1C1MA [Confc[Archive

    Lifescience Database Archive (English)

    Full Text Available n>1DSUA SVQLN----GAHLC >EEEE ---- Eucture... A 1C1MA SLQYRSGSSWAHTC ...>EEEEEE EEE E> ATOM 123 CA SER A 32 -2.328 59.41...CAESN-RRDSC e>EE - EEEture...ence>CAGGDGVRSGC >EE EEE> ATOM 1

  20. 33 CFR 100.113 - Provincetown Harbor Swim for Life, Provincetown, MA.

    Science.gov (United States)

    2010-07-01

    ... 33 Navigation and Navigable Waters 1 2010-07-01 2010-07-01 false Provincetown Harbor Swim for Life, Provincetown, MA. 100.113 Section 100.113 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY REGATTAS AND MARINE PARADES SAFETY OF LIFE ON NAVIGABLE WATERS § 100.113 Provincetown Harbor...

  1. 33 CFR 100.116 - Swim Buzzards Bay Day, New Bedford, MA.

    Science.gov (United States)

    2010-07-01

    ... 33 Navigation and Navigable Waters 1 2010-07-01 2010-07-01 false Swim Buzzards Bay Day, New Bedford, MA. 100.116 Section 100.116 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY REGATTAS AND MARINE PARADES SAFETY OF LIFE ON NAVIGABLE WATERS § 100.116 Swim Buzzards Bay...

  2. Data of evolutionary structure change: 1BEDA-2B6MA [Confc[Archive

    Lifescience Database Archive (English)

    Full Text Available 1BEDA-2B6MA 1BED 2B6M A A AQFKEGEHYQVLKTPASSSPVVSEFFSFYCPHCNTF---...HHHHHHHHHH EEEE EEEEE HHHHHHHHHHHHHH - 0 1BED... A 1BEDA HCNTF---E...e> ALA CA 306 SER CA 272 1BED... A 1BEDA HTLRKPPKDEQ

  3. Oh oleksin ma rikas! : [luuletused] / Hans Christian Andersen ; tlk. Harald Rajamets

    Index Scriptorium Estoniae

    Andersen, Hans Christian, 1805-1875

    2004-01-01

    Sisu: Oh oleksin ma rikas! ; Tädi prillid ; "Oh vägev surm, sa külvad tummalt õudu..." ; "Meil maa peal elu kurblik näib..." ; "Kõik kaob nagu tuul siin ära..." ; "Lund on veel maas ja vahel teeb tuisku..."

  4. Treatment of Chronic Bronchitis with Modified Ma Xing Shi Gan Tang and Er Chen Tang

    Institute of Scientific and Technical Information of China (English)

    朱颖; 刘晓东

    2004-01-01

    @@ Chronic bronchitis is a disease commonly seen in the clinic. The authors have treated 78 cases of the disease with modified Ma Xing Shi Gan Tang (麻杏石甘汤 Decoction of Ephedra, Armeniacae Amarum, Glycyrrhizae and Gypsum Fibrosum) plus Er Chen Tang (二陈汤 Two Old Drugs Decoction). The results were satisfactory and reported as follows.

  5. Mažeikiai naftatehas võib minna Vene kontrolli alla / Kaivo Kopli

    Index Scriptorium Estoniae

    Kopli, Kaivo

    2010-01-01

    Leedu presidendi Dalia Grybauskaitse sõnul peavad Poola ja Venemaa läbirääkimisi Poola energeetikafirmale PKN Orlen kuuluva Mažeikiai naftatehase müügi üle. PKN eitab läbirääkimiste toimumist

  6. SYNTHESIS AND CHARACTERIZATION OF DVE-CO-MA DERIVATIVES OF CIS- PLATINUM COMPLEXES

    Institute of Scientific and Technical Information of China (English)

    WANG Zhuting

    1989-01-01

    Copolymer of divinyl ether and maleic anhydride (DVE- co - MA) derivatives of cis- platinum complexes were synthesized and characterized by elementary analysis, IR and XPS ( X- ray photoelectron spectroscopy). The behavior of the products in biological environment was also studied. UV- visible and fluorescence spectra show that these polymer derivatives are able to exchange ligands with selected nucleophilic groups in biological environment.

  7. 42 CFR 422.216 - Special rules for MA private fee-for-service plans.

    Science.gov (United States)

    2010-10-01

    ... appropriate explanation of benefits. The explanation must include a clear statement of the enrollee's... member. (iv) Any party to which the provider makes assignment or reassigns benefits. (2) The MA... enrollee. (D) The information described in § 422.202(a)(1). (3) Announcements in newspapers, journals,...

  8. The nuclear mitotic apparatus (NuMA) protein: localization and dynamics in human oocytes, fertilization and early embryos.

    Science.gov (United States)

    Alvarez Sedó, Cristian; Schatten, Heide; Combelles, Catherine M; Rawe, Vanesa Y

    2011-06-01

    The oocyte's meiotic spindle is a dynamic structure that relies on microtubule organization and regulation by centrosomes. Disorganization of centrosomal proteins, including the nuclear mitotic apparatus (NuMA) protein and the molecular motor complex dynein/dynactin, can lead to chromosomal instability and developmental abnormalities. The present study reports the distribution and function of these proteins in human oocytes, zygotes and early embryos. A total of 239 oocytes, 90 zygotes and discarded embryos were fixed and analyzed with confocal microscopy for NuMA and dynactin distribution together with microtubules and chromatin. Microtubule-associated dynein-dependent transport functions were explored by inhibiting phosphatase and ATPase activity with sodium-orthovanadate (SOV). At germinal vesicle (GV) stages, NuMA was dispersed across the nucleoplasm. After GV breaks down, NuMA became cytoplasmic before localizing at the spindle poles in metaphase I and II oocytes. Aberrant NuMA localization patterns were found during oocyte in vitro maturation. After fertilization, normal and abnormal pronuclear stage zygotes and embryos displayed translocation of NuMA to interphase nuclei. SOV treatment for up to 2 h induced lower maturation rates with chromosomal scattering and ectopic localization of NuMA. Accurate distribution of NuMA is important for oocyte maturation, zygote and embryo development in humans. Proper assembly of NuMA is likely necessary for bipolar spindle organization and human oocyte developmental competence.

  9. Fermented herbal formula KIOM-MA-128 protects against acute colitis induced by dextran sodium sulfate in mice.

    Science.gov (United States)

    Kim, Dong-Gun; Lee, Mi-Ra; Yoo, Jae-Myung; Park, Kwang-Il; Ma, Jin-Yeul

    2017-07-05

    Colitis is a well-known subtype of inflammatory bowel disease and is caused by diverse factors. Previous research has shown that KIOM-MA elicits anti-inflammatory and anti-allergic effects on various diseases. KIOM-MA-128, our novel herbal formula, was generated from KIOM-MA using probiotics to improve the therapeutic efficacy. We investigated whether KIOM-MA-128 has protective activity in a mouse model of acute colitis induced by dextran sodium sulfate (DSS). Colitis was induced by DSS administered to ICR mice in drinking water. KIOM-MA-128 (125 or 250 mg/kg) was orally administered once per day. The body weights of the mice were measured daily, and colonic endoscopies were performed at 5 and 8 days. Colon length as well as histological and cytokine changes were observed at the end of drug administration. KIOM-MA-128 has pharmacological activity in an acute colitis model. KIOM-MA-128 reduced the loss of body weight and disease activity index (DAI) and inhibited the abnormally short colon lengths and the colonic damage in this mouse model of acute colitis. Moreover, KIOM-MA-128 suppressed pro-inflammatory cytokine expression and maintained the integrity of the tight junctions during DSS-induced colitis. The results indicated that KIOM-MA-128 protects against DSS-induced colitis in mice and suggested that this formula might be a candidate treatment for inflammatory bowel disease (IBD).

  10. Ispitivanje ovladanosti mađarskim kao stranim jezikom u sklopu državno akreditiranih ispitnih sustava u Mađarskoj

    OpenAIRE

    Žagar-Szentesi, Orsolya

    2008-01-01

    U radu će se kratko prikazati način kako se desetljećima uhodani sustav tzv. državnoga ispitivanja sa svojim monocentričnim režimom provjere znanja i trostupnjevitom skalom vrjednovanja ovladanosti stranim jezikom tijekom devedesetih godina postupno prilagodio europskim standardima textsc{(cef)} koji danas u potpunosti obilježavaju mađarsku scenu poučavanja stranih jezika i ispitivanja. Također će se dati sažet pregled o institucionalnim okvirima ispitivanja (Centar za ak...

  11. Research on MA700 Aircraft Work Breakdown Structure Method%MA700飞机工作分解结构方法研究

    Institute of Scientific and Technical Information of China (English)

    肖君

    2014-01-01

    This paper introduces the concept of work breakdown structure and its application in the aviation field ,and puts forward the corresponding solutions to problems that MA 700 aircraft is likely to encounter .%介绍了项目工作分解的概念,以及航空领域的应用情况。针对M A700飞机可能遇到的问题,提出相应的解决思路。

  12. Comparison of AcrySof MA30BA and Sensar AR40 acrylic intraocular lenses.

    Science.gov (United States)

    Casprini, Fabrizio; Tosi, Gian Marco; Quercioli, Pier Paolo; Caporossi, Aldo

    2002-07-01

    To compare differences in anterior (ACO) and posterior (PCO) capsule opacification and subjective glare between 2 acrylic intraocular lenses (IOLs): AcrySof MA30BA (Alcon) and Sensar AR40 (Allergan). Department of Ophthalmology and Neurosurgery, University of Siena, Siena, Italy. This retrospective study comprised 100 cataract patients who had phacoemulsification and IOL implantation. Fifty eyes of 50 patients received an MA30BA and 50 eyes of 50 patients, an AR40. The mean postoperative follow-up was 25 months (range 20 to 31 months) and 22 months (range 19 to 29 months), respectively. Examiners subjectively evaluated ACO, and a photographic image-analysis system was used to assess PCO. All patients received a questionnaire to evaluate the incidence of subjective photic phenomena. In the MA30BA group, 60% had no ACO, 19% had mild ACO, and 21% had anterior capsule fibrosis. In the AR40 group, 55% had no ACO, 27% had mild ACO, and 18% had anterior capsule fibrosis. In the MA30BA group, the mean PCO score measured by image-analysis was 0.043 (range 0.000 to 0.084) at 1 year and 0.125 (range 0.000 to 0.197) at 2 years and in the AR40 group, 0.071 (range 0.000 to 0.157) and 0.230 (range 0.091 to 0.628), respectively. Although the ACO percentages and the PCO scores at 1 year were not statistically different between the 2 groups (P >.05), the MA30BA group had statistically less PCO at 2 years (P .05). The findings indicate that the AcrySof MA30BA has a lower incidence of PCO than the Sensar AR40. The AR40 IOL induced less glare; however, the glare phenomena did not disturb those with an MA30BA lens and the symptoms decreased by 1 year after surgery. These results suggest that both optic design and haptic material influence postoperative clinical results.

  13. Slow steady exhumation of the high elevation Deosai Plateau (Northern Pakistan Himalaya) since 40 Ma

    Science.gov (United States)

    van Melle, J.; van der Beek, P.; Guillot, S.; Pecher, A.; Latif, M.

    2007-12-01

    Mountain ranges of the north-western Himalaya in Pakistan show strongly contrasting relief, opposing steep, deeply incised topography with extremely high peaks such as the Karakorum Range and Nanga Parbat Haramosh Massif (NPHM), to high-altitude, low-relief areas such as the Deosai Plateau located between the Karakorum and NPHM and the Tso-Morari Massif in Eastern Ladakh. In contrast, mean elevations of the different mountain ranges are comparable, the Deosai Plateau being on average even slightly higher than the adjacent NPHM. The aim of this study is to quantify the exhumation history the Deosai Plateau, in order to understand how to build such a high-altitude, low-relief plateau and how to preserve it over million-year timescales. Here, we report the first low-temperature thermochronologic data from the Deosai Plateau, to compare its exhumation history to that of the surrounding massifs. Apatite Fission Track (AFT) ages reported in the literature from the NPHM and Karakorum are extremely young (1 km/Ma. In contrast, our AFT ages from the Deosai Plateau are 15-27 Ma; an order of magnitude older than those of the surrounding massifs. Zircon and apatite (U-Th)/He ages (measured at U of Arizona, HeDWaAZ program) range from 23-45 Ma, and 12-15 Ma, respectively. Modeling the combined AFT and He ages requires continuous and very slow long term cooling rates (around 4 ° C/Ma), consistent with an exhumation rate of about 0.15 km/Ma for typical geothermal gradients. Our data thus suggest steady slow unroofing of the Deosai Plateau since at least 40 Ma. A clear link between cooling age patterns and the geomorphology is also evident, with strongly incised, high-relief massifs showing exhumation at rates an order of magnitude faster than the low-relief plateau. AFT and ZFT ages similar to our data have been reported from the Tso Morari massif further east, characterised by similar high-elevation low-relief morphology. These morphologic zones cross the Indus and Shyok Suture

  14. Under-performance of listed companies? Real earnings management and M&A: Chinese empirical evidence

    Directory of Open Access Journals (Sweden)

    Ziqiao Zhang

    2015-04-01

    Full Text Available Purpose: The purpose of this paper is to examine whether acquiring firms attempt to adopt real earnings management strategy to upward reported earnings in the period of M&A announcement and provide an explanation for the underperformance of post-M&A in share payment M&A affairs occurring in China’s capital market from 2008-2010. Design/methodology/approach: The author uses Roychowdhury’s(2006 methodology to measure the magnitude of real earnings management of acquiring firms in stock for stock M&A by exploiting financial date from 2006 to 2011. The methodology includes three models, which are cash ?ow from operations, production costs and discretionary expenditures, respectively. Findings: It was found that firms using stock as a financing medium exhibit significant negative abnormal cash flows and abnormal discretionary expenses yet abnormal production costs significantly positive during the current period of M&A. Moreover, it was also documented that acquiring firms use real activities manipulation to overstate earnings for the purpose of improving market confidence. Finally, a negative association was found between REM and under-performance of post-M&A. Research limitations/implications: To some extent, these results explain the puzzle of performance decline over the following period of post-M&A. Meanwhile, our study adds to prior literature that capital market pressures induce acquiring firms inflate reported earnings by manipulating real activities in stock-financed M&A occurring in China’s capital market. Practical implications: The author’s result imply that investors, analysts and regulators cannot ignore more undetectable opportunism behaviors underlying reported earnings than accrual-based earnings management and the impact on the performance of post-M&A when they use financial statements to evaluate acquiring firms. Social implications: Our study plays important role in making public policies. Furthermore, it is necessary to

  15. Pfister y la Hibridación del Maíz

    Directory of Open Access Journals (Sweden)

    Kent. George

    1940-03-01

    Full Text Available En la Facultad Nacional de Agronomía, se están haciendo actualmente los trabajos de aclimatación del "maíz hibrido Pfister". Cuando el suscrito tuvo conocimiento del "maíz híbrido" obtenido como fruto de una experimentación de más de 20 años llevada a cabo en Illinois por el señor Pfister, se interesó vivamente en traer unas semillas a Colombia para intentar el proceso de aclimatación de las mejores variedades. A pesar de una larga correspondencia con el señor Pfister desde hace dos años, no nos fue posible lograr nuestro objeto. Durante la última visita del suscrito a ese país, obtuve, como una merced personal, una muy pequeña cantidad de las ocho mejores variedades de maíz híbrido, y al efecto, a la presente le estoy incluyendo a usted esas semillas de maíz sin otra retribución para nosotros, que el de hacer las siembras, observaciones y experimentaciones con todo el cuidado de que usted es capaz, y darnos cuenta oportuna de los resultados obtenidos con cada una de las variedades. Cada talego está marcado con el número de la variedad y no está por demás rogar a usted de la manera más encarecida llevar a efecto este trabajo con el mayor cuidado e interés para corresponder por lo menos al que hemos tenido nosotros en proporcionarle las dichas semillas. A pesar de que en Estados Unidos han hecho una súper selección de maíz en los últimos 50 años, las semillas seleccionadas han; quedado superadas por el maíz "Híbrido Pfister" con rendimientos de más de un 60%. Como nosotros no hemos hecho nada en selección de maíz, nuestro trabajo se puede limitar a un proceso de "aclimatación", que si logramos, tendríamos ganados muchos años de trabajo.

  16. Mapping Nearby Galaxies at APO: The MaNGA IFU Galaxy Survey

    Science.gov (United States)

    Law, David R.; MaNGA Team

    2014-01-01

    MaNGA is a new survey that will begin in August 2014 as part of SDSS-IV with the aim of obtaining integral-field spectroscopy for an unprecedented sample of 10,000 nearby galaxies. MaNGA's key goals are to understand the "life cycle" of present day galaxies from imprinted clues of their birth and assembly, through their ongoing growth via star formation and merging, to their death from quenching at late times. To achieve these goals, MaNGA will channel the impressive capabilities of the SDSS-III BOSS spectrographs in a fundamentally new direction by marshaling the unique power of 2D spectroscopy. MaNGA will deploy 17 pluggable Integral Field Units (IFUs) made by grouping fibers into hexagonal bundles ranging from 19 to 127 fibers each. The spectra obtained by MaNGA will cover the wavelength range 3600-10,000 Angstroms (with a velocity resolution of ~ 60 km/s) and will characterize the internal composition and the dynamical state of a sample of 10,000 galaxies with stellar masses greater than 10^9 Msun and an average redshift of z ~ 0.03. Such IFU observations enable a leap forward because they provide an added dimension to the information available for each galaxy. MaNGA will provide two-dimensional maps of stellar velocity and velocity dispersion, mean stellar age and star formation history, stellar metallicity, element abundance ratio, stellar mass surface density, ionized gas velocity, ionized gas metallicity, star formation rate, and dust extinction for a statistically powerful sample. This legacy dataset will address urgent questions in our understanding of galaxy formation, including 1) The formation history of galaxy subcomponents, including the disk, bulge, and dark matter halo, 2) The nature of present-day galaxy growth via merging and gas accretion, and 3) The processes responsible for terminating star formation in galaxies. Finally, MaNGA will also play a vital role in the coming era of advanced IFU instrumentation, serving as the low-z anchor for

  17. Characterization of transcriptional profiles of MA-ACS1 and MA-ACO1 genes in response to ethylene, auxin, wounding, cold and different photoperiods during ripening in banana fruit.

    Science.gov (United States)

    Choudhury, Swarup Roy; Roy, Sujit; Sengupta, Dibyendu N

    2008-12-01

    The ripening-specific genes MA-ACS1 (Musa acuminata ACC synthase1) and MA-ACO1 (M. acuminata ACC oxidase 1) are regulated in response to a wide variety of factors. Here, we have studied the differential transcript accumulation pattern and protein levels of MA-ACS1 and MA-ACO1 genes in response to ethylene, auxin, wounding and low temperature in preclimacteric banana fruit. We have shown that exogenous application of ethylene and auxin induced the expression of MA-ACS1, while MA-ACO1 showed marginal expression following ethylene treatment in preclimacteric stage. Auxin did not induce MA-ACO1 expression. Thus, auxin-treated banana fruits showed lower ethylene production rate as compared to ethylene-treated fruits. Conversely, wounding and cold treatment down-regulated the expression of both the genes and thus inhibited ethylene production. Furthermore, we have detected a GCC-box putative ethylene-responsive element (ERE)- and an auxin-responsive element (ARE)-specific DNA-binding activity in the banana pulp and studied the ethylene and auxin responsive characteristics of the GCC-box and ARE (TGTCTC) containing synthetic promoter fragments. In addition, we have detected an enhanced ethylene production rate and expression level of MA-ACS1 and MA-ACO1 genes along with a strong GCC-box-specific DNA-binding activity following exposure to constant dark period for 8d at the preclimacteric stage. Together, our study provides interesting information about the regulation of expression of MA-ACS1 and MA-ACO1 genes in response to various factors during ripening in banana fruit, which may have physiological relevance concerning ethylene biosynthesis during post-harvest conditions.

  18. Geochronological constraints on 140-85 Ma thermal doming extension in the Dabie orogen, central China

    Institute of Scientific and Technical Information of China (English)

    2002-01-01

    Regional architecture of geochronology and differential cooling pattern show that the Dabie orogen underwent a thermal doming extension during 140-85 Ma. This extension resulted in widespread re-melting of the Dabie basement, intense volcanic activities in North Huaiyang and the formation of fault-controlled depressions in the Hefei basin. This thermal doming extension can be further divided into two consecutive evolving stages, i.e. the intensifying stage (140-105 Ma) and the declining stage (105-85 Ma). In the first stage (140-105 Ma), the thermal doming mainly was concentrated in the Dabie block, and to a less degree, in the Hongan block. The thermal doming structure of the Dabie block is configured with Macheng-Yuexi thermal axis, Yuexi/Luotian thermal cores and their downslide flanks. The orientation of thermal axis is dominantly parallel to the strike of orogen, and UHP/HP units together with metamorphic rocks of North Huaiyang constitute the downslide flanks. The Yuexi core differs from the Luotian core in both the intensity and the shaping time. To some extent, the Hongan block can be regarded as part of downslide systems of the Dabie doming structure. The doming process is characterized by thermal-center's migration along the Macheng-Yuexi thermal axis; consequently, it is speculated to be attributed to the convective removal of thickened orogenic root, which is a process characterized by intermittance, migration, large-scale and differentiation. During the declining stage (105-85 Ma), the dome- shaped figure still structurally existed in the Dabie orogen, but orogenic units cooled remarkably slow and magmatic activities stagnated gradually. Study on the thermal doming of Dabieshan Mountains can thus provide detailed constraints on the major tectonic problems such as the UHP/HP exhumation model, the boundary between North Dabie and South Dabie, and the orogenesis mechanism.

  19. The Lake Albert Rift (uganda, East African Rift System): Deformation, Basin and Relief Evolution Since 17 Ma

    Science.gov (United States)

    Brendan, Simon; François, Guillocheau; Cécile, Robin; Olivier, Dauteuil; Thierry, Nalpas; Martin, Pickford; Brigitte, Senut; Philippe, Lays; Philippe, Bourges; Martine, Bez

    2016-04-01

    This study is based on a coupled basin infilling study and a landforms analysis of the Lake Albert Rift located at the northern part of the western branch of the East African Rift. The basin infilling study is based on both subsurface data and outcrops analysis. The objective was to (1) obtain an age model based on onshore mammals biozones, (2) to reconstruct the 3D architecture of the rift using sequence stratigraphy correlations and seismic data interpretation, (3) to characterize the deformation and its changes through times and (4) to quantify the accommodation for several time intervals. The infilling essentially consists of isopach fault-bounded units composed of lacustrine deposits wherein were characterized two major unconformities dated at 6.2 Ma (Uppermost Miocene) and 2.7 Ma (Pliocene-Pleistocene boundary), coeval with major subsidence and climatic changes. The landforms analysis is based on the characterization and relative dating (geometrical relationships with volcanism) of Ugandan landforms which consist of stepped planation surfaces (etchplains and peplians) and incised valleys. We here proposed a seven-steps reconstruction of the deformation-erosion-sedimentation relationships of the Lake Albert Basin and its catchments: - 55-45 Ma: formation of laterites corresponding to the African Surface during the very humid period of the Lower-Middle Eocene; - 45-22: stripping of the African Surface in response of the beginning of the East-African Dome uplift and formation of a pediplain which associated base level is the Atlantic Ocean; - 17-2.5 Ma: Initiation of the Lake Albert Basin around 17 Ma and creation of local base levels (Lake Albert, Edward and George) on which three pediplains tend to adapt; - 18 - 16 Ma to 6.2 Ma: "Flexural" stage (subsidence rate: 150-200 m/Ma; sedimentation rate 1.3 km3/Ma between 17 and 12 Ma and 0.6 km3/Ma from 12 to 6 Ma) - depocenters location (southern part of Lake Albert Basin) poorly controlled by fault; - 6.2 Ma to 2

  20. 基于MaSE的软件开发及应用%Application of software development based on MaSE

    Institute of Scientific and Technical Information of China (English)

    罗东俊

    2007-01-01

    目前智能分布式应用系统需求日益增强,对这类系统的开发是现阶段软件工程面临的一个巨大挑战.MaSE(Multiagent System Engineering)方法以主体理论和技术为基础,充分借鉴面向对象软件开发方法的思想,为开发智能分布式系统提供了较大通用性.分析了MaSE方法的建模技术,并把该方法应用于计算机系统安全监控软件开发中.与现有的其他软件开发方法(如结构化、面向对象)相比较,它在系统的自然建模、管理和控制系统复杂性、提高目标软件系统的灵活性、可维护性和可重用性等方面具有较大优越性.

  1. Efecto del Extracto de Estigmas de Maíz sobre Aspergillus spp Efecto del Extracto de Estigmas de Maíz sobre Aspergillus spp

    Directory of Open Access Journals (Sweden)

    Hugo Alberto Luna Olvera

    2012-02-01

    Full Text Available Un extracto de estigmas del híbrido de maíz A-791 fue adicionado a un medio de cultivo, evaluándose su efecto sobre el crecimiento, esporulación y síntesis de micotoxinas de Aspergillus parasiticus ATCC 16992 y A. nidulans FGSC-26. Se encontró un efecto estimulatorio en el crecimiento de ambos hongos y la esporulación del primero, contrastado con el efecto inhibitorio en la síntesis de aflatoxinas de A. parasiticus y estimulatorio en la de esterigmatocistina de A. nidulans. Los resultados sugieren la presencia de compuestos en los estigmas frescos del maíz que estimulan el crecimiento y esporulación de A. parasiticus, pero inhiben la síntesis de aflatoxinas.A silk (stigmas extract of hybrid A-791 of maize was added to synthetic culture, evaluating its effect on growth, sporulation and synthesis of micotoxins of Aspergillus parasiticus ATCC 16992 and A. nidulans FGSC-26. It was observed a stimulatory effect in growth of both fungi and sporulation of on the first, contrasting with inhibiting effect in the synthesis of afl atoxins of A. parasiticus and stimulatory in the sterigmatocystin of A. nidulans. Results suggest the presence of compound in stigmas fresh of maize that stimulate the growth and sporulation of A. parasiticus, but inhibit the aflatoxins synthesis.

  2. SDSS IV MaNGA—Rotation Velocity Lags in the Extraplanar Ionized Gas from MaNGA Observations of Edge-on Galaxies

    Science.gov (United States)

    Bizyaev, D.; Walterbos, R. A. M.; Yoachim, P.; Riffel, R. A.; Fernández-Trincado, J. G.; Pan, K.; Diamond-Stanic, A. M.; Jones, A.; Thomas, D.; Cleary, J.; Brinkmann, J.

    2017-04-01

    We present a study of the kinematics of the extraplanar ionized gas around several dozen galaxies observed by the Mapping of Nearby Galaxies at the Apache Point Observatory (MaNGA) survey. We considered a sample of 67 edge-on galaxies out of more than 1400 extragalactic targets observed by MaNGA, in which we found 25 galaxies (or 37%) with regular lagging of the rotation curve at large distances from the galactic midplane. We model the observed Hα emission velocity fields in the galaxies, taking projection effects and a simple model for the dust extinction into account. We show that the vertical lag of the rotation curve is necessary in the modeling, and estimate the lag amplitude in the galaxies. We find no correlation between the lag and the star formation rate in the galaxies. At the same time, we report a correlation between the lag and the galactic stellar mass, central stellar velocity dispersion, and axial ratio of the light distribution. These correlations suggest a possible higher ratio of infalling-to-local gas in early-type disk galaxies or a connection between lags and the possible presence of hot gaseous halos, which may be more prevalent in more massive galaxies. These results again demonstrate that observations of extraplanar gas can serve as a potential probe for accretion of gas.

  3. REGENERASI DAN PERBANYAKAN RUMPUT LAUT Kappaphycus alvarezii HASIL TRANSFORMASI GEN SUPEROKSIDA DISMUTASE (MaSOD

    Directory of Open Access Journals (Sweden)

    Emma Suryati

    2017-01-01

    Full Text Available Transformasi gen superoxide dismutase (MaSOD pada rumput laut Kappaphycus alvarezii menggunakan Agrobacterium tumefacient telah dilakukan secara in vitro. Transformasi gen MaSOD ke dalam genom rumput laut diharapkan dapat mengurangi cekaman oksidatif terutama yang disebabkan oleh perubahan suhu, salinitas, dan cemaran logam di perairan. Penelitian ini bertujuan untuk regenerasi rumput laut hasil introduksi gen MaSOD dan non-transgenik pada labu kultur. Regenerasi dan perbanyakan rumput laut hasil transformasi gen MaSOD dilakukan di laboratorium pada labu kultur yang diletakkan dalam “culture chamber” yang dilengkapi dengan aerasi menggunakan media kultur yang diperkaya dengan pupuk PES, Grund, Conwy, dan SSW sebagai kontrol, salinitas 20, 25, 30, 35, dan 40 g/L, pH 4, 5, 6, 7, dan 8. Intensitas cahaya antara 500-2.000 lux dengan fotoperiode terang dan gelap 8:16; 12:12; dan 16:8. Untuk merangsang pertumbuhan eksplan dilakukan pemeliharaan dengan penambahan hormon tumbuh IAA dan BAP dengan perbandingan 1:1, 1:2, dan 2:1. Penelitian dilakukan secara bertahap. Evaluasi transgenik dilakukan menggunakan teknik PCR. Hasil penelitian memperlihatkan bahwa sintasan yang paling tinggi diperoleh menggunakan media PES (94%, salinitas 30 g/L (90%, pH 7 (96%, intensitas cahaya pada 1.500 lux (80%, fotoperiode 12:12 (84%, komposisi ZPT dengan campuran IAA dan BAP dengan perbandingan 2:1. Hasil analisis PCR memperlihatkan K. alvarezii transgenik putatif mengandung transgen MaSOD sebanyak 78% dari hasil transformasi. Superoxide dismutase transformation (MaSOD gene of seaweed Kappaphycus alvarezii mediated by Agrobacterium tumefacient has been successfully done in vitro. MaSOD genes introduced into the seaweed genome is expected to reduce oxidative stress caused by environmental conditions such as changes in temperature, salinity and metal contamination of the water. This study aimed to regenerate both the MaSOD transformed seaweed and non-transgenic in a

  4. Preliminary experiments to estimate the PE.MA.M (PElagic MArine Mesocosm) offshore behaviour

    Science.gov (United States)

    Albani, Marta; Piermattei, Viviana; Stefanì, Chiara; Marcelli, Marco

    2016-04-01

    The phytoplankton community is controlled not only by local environmental conditions but also by physical processes occurring on different temporal and spatial scales. Hydrodynamic local conditions play an important role in marine ecosystems. Several studies have shown that hydrodynamic conditions can influence the phytoplankton settling velocity, vertical and horizontal distribution and formation of cyanobacterial blooms. Mesocosms are useful structures to simulate marine environment at mesoscale resolution; allowing to closely approximate biotic or abiotic parameters of interest directly in nature. In this work an innovative structure named PE.MA.M (PElagic MArine Mesocosm) is presented and tested. Laboratory experiments have been conducted in order to observe seasonal variations of biomass behaviour in two different hydrodynamic conditions: outside as well as whithin the PE.MA.M. We have evaluated whether it is possible to isolate a natural system from external water mass hydrodynamic exchanges and to assume that phytoplankton cells' transition is limited at the net and sea interface. Preliminary experiments test the isolating capacity of the net, to determine the currents' attenuation rate and to estimate the possible PE.MA.M. offshore behaviour. In the first investigation, we monitored the diffusion of phytoplankton cells. The PE.MA.M. exterior and interior were simulated using a plexiglass tank divided into two half-tanks (Aout-Bin) by a septum consisting of a net like a PE.MA.M. The tank was filled up with 10 L of water and only the half-tank Aout was filled up with 10 ml of phytoplankton culture (Clorella sp.). We monitored the chlorophyll concentrations for 24 hours. The two tanks had similar concentrations after 4 hours (2.70322 mg/m³ Aout and 2.37245 mg/m3 Bin) and this constant relationship was maintened until the end of the test. In the second investigation we used clod cards to measure water motions.We conducted two experiments within tank, the first

  5. High-resolution estimates of Southwest Indian Ridge plate motions, 20 Ma to present

    Science.gov (United States)

    DeMets, C.; Merkouriev, S.; Sauter, D.

    2015-12-01

    We present the first estimates of Southwest Indian Ridge (SWIR) plate motions at high temporal resolution during the Quaternary and Neogene based on nearly 5000 crossings of 21 magnetic reversals out to C6no (19.72 Ma) and the digitized traces of 17 fracture zones and transform faults. Our reconstructions of this slow-spreading mid-ocean ridge reveal several unexpected results with notable implications for regional and global plate reconstructions since 20 Ma. Extrapolations of seafloor opening distances to zero-age seafloor based on reconstructions of reversals C1n (0.78 Ma) through C3n.4 (5.2 Ma) reveal evidence for surprisingly large outward displacement of 5 ± 1 km west of 32°E, where motion between the Nubia and Antarctic plates occurs, but 2 ± 1 km east of 32°E, more typical of most mid-ocean ridges. Newly estimated SWIR seafloor spreading rates are up to 15 per cent slower everywhere along the ridge than previous estimates. Reconstructions of the numerous observations for times back to 11 Ma confirm the existence of the hypothesized Lwandle plate at high confidence level and indicate that the Lwandle plate's western and eastern boundaries respectively intersect the ridge near the Andrew Bain transform fault complex at 32°E and between ˜45°E and 52°E, in accord with previous results. The Nubia-Antarctic, Lwandle-Antarctic and Somalia-Antarctic rotation sequences that best fit many magnetic reversal, fracture zone and transform fault crossings define previously unknown changes in the Neogene motions of all three plate pairs, consisting of ˜20 per cent slowdowns in their spreading rates at 7.2^{+0.9 }_{ -1.4} Ma if we enforce a simultaneous change in motion everywhere along the SWIR and gradual 3°-7° anticlockwise rotations of the relative slip directions. We apply trans-dimensional Bayesian analysis to our noisy, best-fitting rotation sequences in order to estimate less-noisy rotation sequences suitable for use in future global plate reconstructions

  6. M. Mažvydo raštų kalba

    Directory of Open Access Journals (Sweden)

    Zigmas Zinkevičius

    2011-07-01

    Full Text Available THE LANGUAGE OF MAŽVYDAS' WRITINGSSummaryThe native dialect of Martynas Mažvydas — the author of the first Lithuanian printed book—has not yet been established. Some investigators (A. Schleicher, V. Grinaveckis have con­sidered him to be born in the region of Klaipėda or generally in the Dukedom of Prussia (P. Pakarklis, other scholars (K. Būga, Chr. S. Stang, J. Senkus considered him to have come from the north-western part of the Samogitian dialect area, still others (A. Salys — from the south-eastern part of that dialect area. However, in their investigations they all confined themselves solely to the linguistic analysis of the first Lithuanian book — Mažvydas' Catechism of 1547, while his other writings were almost totally ignored.The author of the present paper conducted a linguistic research of all Mažvydas' writings, including a better copy of the Catechism of 1547, obtained from the M. Gorky Library of Odessa and at the present time preserved at the Vilnius University Library. Dialect features of the writings were compared in great detail to the corresponding peculiarities of the present-day Lithuanian dialects and in the first place to those of the Samogitian dialects.The conclusions of the study were presented in the article published in parts in Baltistica, vols. XIII, 2, XIV, 1 — 2 and XV, 1. The following are the main conclusions of the study.Mažvydas' native dialect is to be localized in the south-western part of Southern Samogitian area; cf. the map in Baltistica XIII, 2, p. 369.The High Lithuanian dialectal characteristics appeared in the first Lithuanian book not due to Mažvydas' conscious efforts to conform to High Lithuanian (as previously many scholars were apt to assume but owing to his being born in a dialectally mixed family: his father must have been a Samogitian, whereas his mother was a western High Lithuanian, a speaker of its northern subdialect. The analysis of Mažvydas' early writings (Baltistica

  7. Synthesis and Evaluation of Water Soluble MA/SAS Polymer Scale Inhibitor%MA/SAS水溶性聚合物阻垢剂的合成与评价

    Institute of Scientific and Technical Information of China (English)

    王忠辉; 刘庆旺

    2005-01-01

    以马来酸酐(MA)和烯丙基磺酸钠(SAS)为原料,制得MA/SAS水溶性聚合物阻垢剂.确定了最佳工艺条件:n(MA):n(SAS)=1:1,体系pH值4.0~4.5,反应温度75~80℃,反应时间4~5 h.MA/SAS水溶性聚合物阻垢性能优于现在常用的阻垢剂HEDP,并与其他油田常用药剂具有良好的配伍性.在现场试验中,MA/SAS聚合物阻垢剂阻垢率可达90%,效果明显.

  8. MA Doping Analysis on Breeding Capability and Protected Plutonium Production of Large FBR

    Science.gov (United States)

    Permana, Sidik; Suzuki, Mitsutoshi; Kuno, Yusuke

    2010-06-01

    Spent fuel from LWR can be seen as long-live waste if it is not recycled or as a "new fuel" resource if it is recycled into the reactors. Uranium and plutonium have been used for "new fuel" resources from LWR spent fuel as MOX fuel type which is loaded into thermal reactor or fast reactor types. Other actinides from the spent fuel such as neptunium, americium and curium as minor actinide (MA) are considered to be loaded into the reactors for specific purposes, recently. Those purposes such as for increasing protected plutonium production and breeding capability for protected plutonium as well as in the same time those amount of MA can be reduced to a small quantity as a burner or transmutation purpose. Some investigations and scientific approaches are performed in order to increase a material "barrier" in plutonium isotope composition by increasing the even mass number of plutonium isotope such as Pu-238, Pu-240 and Pu-242 as plutonium protected composition. Higher material barrier which related to intrinsic properties of plutonium isotopes with even mass number (Pu-238, Pu-240 and Pu-242), are recognized because of their intense decay heat (DH) and high spontaneous fission neutron (SFN) rates. Those even number mass of plutonium isotope contribute to some criteria of plutonium characterization which will be adopted for present study such as IAEA, Pellaud and Kessler criteria (IAEA, 1972; Pellaud, 2002; and Kessler, 2007). The present paper intends to evaluate the breeding capability as a fuel sustainability index of the reactors and to analyze the composition of protected plutonium production of large power reactor based on the FaCT FBR as reference (Ohki, et al., 2008). Three dimensional FBR core configuration has been adopted which is based on the core optimization calculation of SRAC-CITATION code as reactor core analysis and JENDL-3.3 is adopted for nuclear data library. Some MA doping materials are loaded into the blanket regions which can be considered as

  9. Spreading behaviour of the Pacific-Farallon ridge system since 83 Ma

    Science.gov (United States)

    Rowan, Christopher J.; Rowley, David B.

    2014-06-01

    We present improved rotations, complete with uncertainties, for the Pacific-Farallon Ridge (PFR) between geomagnetic chrons 34y (83 Ma) and 10y (28.28 Ma). Despite substantial shortening since ˜55 Ma, this ridge system and its remnants (e.g. the East Pacific Rise) have produced as much as 45 per cent of all oceanic lithosphere created since the Late Cretaceous, but reconstructions face the twin challenges of extensive subduction of Farallon crust-which precludes reconstruction by fitting conjugate magnetic anomaly and fracture zone (FZ) traces-and asymmetric spreading behaviour for at least the past 51 Myr. We have calculated best-fit `half'-angle stage rotations between nine geomagnetic chron boundaries (34y, 33y, 29o, 24.3o, 20o, 18.2o, 17.1y, 13y and 10y) using combined anomaly and FZ data from both the northern and southern Pacific Plate. For rotations younger than chron 24.3o, estimates for spreading asymmetry, derived using anomaly picks from yet-to-be subducted Farallon/Nazca crust in the south Pacific, allow full stage rotations to be calculated. Between 50 and 83 Ma, where no direct constraints on spreading asymmetry are possible, a `best-fit' full stage rotation was calculated based on the net Nazca:Pacific spreading asymmetry (Pacific spreading fraction fPAC = 0.44) over the past 50 Myr, with conservative lower and upper bounds, based on variability in the degree of spreading asymmetry over periods of fPACs of 0.5 and 0.36, respectively. Synthetic flowlines generated from our new stage rotation produce a better match to Pacific FZ trends than previously published rotations. With the exception of the chron 18o-20o rotation, the six stage poles for rotations between chrons 33y and 13y (74-33 Ma) all cluster tightly at 60-75°E, 60-68°N, consistent with the relatively constant trend of the major Pacific FZs. This stability spans at least one episode of Farallon Plate fragmentation caused by subduction of PFR segments beneath the Americas, at 55-48 Ma

  10. Yoghurt fermentation characteristics of Lactobacillus plantarum MA2 strain from kefir grains%Kefir源植物乳杆菌MA2的牛乳发酵特性研究

    Institute of Scientific and Technical Information of China (English)

    许女; 王艳萍; 习傲登; 张玢

    2011-01-01

    Yoghurt fermentation characteristics of Lactobacillus plantaium MA2 strain from Kefir Grains was studied in this experiment. The results showed that post-acidification degree of L. plantarvm MA2 yoghurt was significantly reduced compared with that of ordinary yoghurt during storage at 4℃ for 21d refrigeration period. In addition, the viscosity of MA2 yoghurt was enhanced and the whey separation rate was decreased. Moreover, the sensory evaluation results showed that, compared with that of the ordinary yogurt, the MA2 yogurt taste is more delicate, soft smooth, thick and u-niform. Based on the earlier experiment results, it was found that MA2 strain can degrade cholesterol and develop intestinal flora. Therefore, it has a good application in dairy probiotics production.%该试验对Kefir源植物乳杆菌MA2的牛乳发酵特性进行了研究,结果显示,在4℃、21d的冷藏期间内,相比较于普通酸奶,添加了植物乳杆菌MA2的益生菌酸奶的后酸化程度显著降低;且MA2菌株提高了酸奶的黏度,降低了储存期间酸乳的乳清析出率;另外,感官评价结果显示,MA2菌株发酵的酸奶口感更加细腻、绵滑、黏稠、均匀,香气更加浓郁;基于前期试验证明MA2菌株还具有降胆固醇、调节肠道菌群的生理功能,因此其具有良好的乳制品益生菌发酵剂应用前景.

  11. Overview of the SDSS-IV MaNGA Survey: Mapping nearby Galaxies at Apache Point Observatory

    NARCIS (Netherlands)

    Bundy, Kevin; Bershady, Matthew A.; Law, David R.; Yan, Renbin; Drory, Niv; MacDonald, Nicholas; Wake, David A.; Cherinka, Brian; Sánchez-Gallego, José R.; Weijmans, Anne-Marie; Thomas, Daniel; Tremonti, Christy; Masters, Karen; Coccato, Lodovico; Diamond-Stanic, Aleksandar M.; Aragón-Salamanca, Alfonso; Avila-Reese, Vladimir; Badenes, Carles; Falcón-Barroso, Jésus; Belfiore, Francesco; Bizyaev, Dmitry; Blanc, Guillermo A.; Bland-Hawthorn, Joss; Blanton, Michael R.; Brownstein, Joel R.; Byler, Nell; Cappellari, Michele; Conroy, Charlie; Dutton, Aaron A.; Emsellem, Eric; Etherington, James; Frinchaboy, Peter M.; Fu, Hai; Gunn, James E.; Harding, Paul; Johnston, Evelyn J.; Kauffmann, Guinevere; Kinemuchi, Karen; Klaene, Mark A.; Knapen, Johan H.; Leauthaud, Alexie; Li, Cheng; Lin, Lihwai; Maiolino, Roberto; Malanushenko, Viktor; Malanushenko, Elena; Mao, Shude; Maraston, Claudia; McDermid, Richard M.; Merrifield, Michael R.; Nichol, Robert C.; Oravetz, Daniel; Pan, Kaike; Parejko, John K.; Sanchez, Sebastian F.; Schlegel, David; Simmons, Audrey; Steele, Oliver; Steinmetz, Matthias; Thanjavur, Karun; Thompson, Benjamin A.; Tinker, Jeremy L.; van den Bosch, Remco C. E.; Westfall, Kyle B.; Wilkinson, David; Wright, Shelley; Xiao, Ting; Zhang, Kai

    2015-01-01

    We present an overview of a new integral field spectroscopic survey called MaNGA (Mapping Nearby Galaxies at Apache Point Observatory), one of three core programs in the fourth-generation Sloan Digital Sky Survey (SDSS-IV) that began on 2014 July 1. MaNGA will investigate the internal kinematic stru

  12. The role of timing in a merger wave on overcoming challenges in the M&A pre-merger process

    NARCIS (Netherlands)

    Trang, T.D.; Rao Sahib, P.; van Witteloostuijn, Arjen

    This paper investigates two important issues in the pre-merger process, namely the probability to complete an announced M&A deal and the time needed to complete the process. First, through a content analysis of the 150 largest abandoned announced M&A deals between 2000 and 2010, we demonstrate that

  13. A new pollen record of the last 2.8 Ma from the Co Ngoin,central Tibetan Plateau

    Institute of Scientific and Technical Information of China (English)

    吕厚远; 王苏民; 吴乃琴; 童国榜; 羊向东; 沈才明; 李世杰; 朱立平; 旺罗

    2001-01-01

    A new pollen record from the lake of Co Ngoin in the central Tibetan Plateau provides information on the vegetation and climate changes during the last 2.8 Ma. Seven major significant changes in pollen associations indicate the processes of vegetation change and possible tectonic uplifts. The seven changes in vegetation succession include a temperate montane conifer and broad-leaved mixed forest, cold temperate montane dark conifer forest, alpine shrub-meadow and alpine desert, montane dark coniferous forest and alpine shrub meadow, montane dark coniferous forest and alpine shrub meadow, montane dark coniferous forest and alpine meadow, and alpine desert and meadow. The pollen record provides the evidence of at least five times tectonic uplifts occurring at about 2.58 Ma, 1.87 Ma, 1.17 Ma, 0.83 Ma, and 0.3 Ma ago, respectively. Before 0.8 Ma, this region maintained the altitude below 4000 m a.s.l. Larger amplitude of uplift occurring at about 0.8 Ma ago enforced the plateau rising into cryosphere, shapin

  14. 46 CFR 308.536 - Declaration where failure to comply with Clause 21 was inadvertent, Form MA-314.

    Science.gov (United States)

    2010-10-01

    ... inadvertent, Form MA-314. 308.536 Section 308.536 Shipping MARITIME ADMINISTRATION, DEPARTMENT OF... Insurance § 308.536 Declaration where failure to comply with Clause 21 was inadvertent, Form MA-314. An... sufficient to meet the requirements of Clause 21 of the Policy shall file this Declaration, Form...

  15. Synthesis of bis-N-alkyl imidazolium salts and their palladium(0)(NHC)(η2-MA)2 complexes

    NARCIS (Netherlands)

    Tromp, D.S.; Hauwert, P.; Elsevier, C.J.

    2012-01-01

    New N-Alkyl-substituted imidazolium salts as well as a series of their corresponding [Pd(NHC)(MA)2] complexes have been obtained by three routes in good yield. The previously reported synthesis for the analogous N-aryl substituted [Pd(NHC)(MA)2] complexes has been improved. The N-alkyl-substituted

  16. Overview of the SDSS-IV MaNGA Survey: Mapping nearby Galaxies at Apache Point Observatory

    NARCIS (Netherlands)

    Bundy, Kevin; Bershady, Matthew A.; Law, David R.; Yan, Renbin; Drory, Niv; MacDonald, Nicholas; Wake, David A.; Cherinka, Brian; Sánchez-Gallego, José R.; Weijmans, Anne-Marie; Thomas, Daniel; Tremonti, Christy; Masters, Karen; Coccato, Lodovico; Diamond-Stanic, Aleksandar M.; Aragón-Salamanca, Alfonso; Avila-Reese, Vladimir; Badenes, Carles; Falcón-Barroso, Jésus; Belfiore, Francesco; Bizyaev, Dmitry; Blanc, Guillermo A.; Bland-Hawthorn, Joss; Blanton, Michael R.; Brownstein, Joel R.; Byler, Nell; Cappellari, Michele; Conroy, Charlie; Dutton, Aaron A.; Emsellem, Eric; Etherington, James; Frinchaboy, Peter M.; Fu, Hai; Gunn, James E.; Harding, Paul; Johnston, Evelyn J.; Kauffmann, Guinevere; Kinemuchi, Karen; Klaene, Mark A.; Knapen, Johan H.; Leauthaud, Alexie; Li, Cheng; Lin, Lihwai; Maiolino, Roberto; Malanushenko, Viktor; Malanushenko, Elena; Mao, Shude; Maraston, Claudia; McDermid, Richard M.; Merrifield, Michael R.; Nichol, Robert C.; Oravetz, Daniel; Pan, Kaike; Parejko, John K.; Sanchez, Sebastian F.; Schlegel, David; Simmons, Audrey; Steele, Oliver; Steinmetz, Matthias; Thanjavur, Karun; Thompson, Benjamin A.; Tinker, Jeremy L.; van den Bosch, Remco C. E.; Westfall, Kyle B.; Wilkinson, David; Wright, Shelley; Xiao, Ting; Zhang, Kai

    We present an overview of a new integral field spectroscopic survey called MaNGA (Mapping Nearby Galaxies at Apache Point Observatory), one of three core programs in the fourth-generation Sloan Digital Sky Survey (SDSS-IV) that began on 2014 July 1. MaNGA will investigate the internal kinematic

  17. Effectiveness of M.A. EPM Program Launched Through Distance Education System of Allama Iqbal Open University Islamabad

    Science.gov (United States)

    Hussain Shah, Syed Manzoor; Ahmad, Masoor

    2014-01-01

    The study focus the effectiveness of the M.A EPM program launched through distance education system of AIOU. For this purpose the performance of heads of educational institutions with and without M.A EPM degree was analyzed keeping in view different major aspects i.e. planning strategies, managerial approaches, coordination, administration and use…

  18. 77 FR 40147 - Pan Am Southern, LLC.-Abandonment Exemption-in Worcester County, MA; Springfield Terminal Railway...

    Science.gov (United States)

    2012-07-06

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF TRANSPORTATION Surface Transportation Board Pan Am Southern, LLC.--Abandonment Exemption--in Worcester County, MA; Springfield Terminal Railway Company--Discontinuance of Service Exemption--in Worcester County, MA Pan Am...

  19. An 8.1Ma calcite record of Asian summer monsoon evolution on the Chinese central Loess Plateau

    Institute of Scientific and Technical Information of China (English)

    CHEN XiuLing; FANG XiaoMin; AN ZhiSheng; HAN WenXia; WANG Xin; BAI Yan; HONG Ye

    2007-01-01

    Carbonates in loess-red clay sequences consist mainly of calcite and dolomite.The EDTA analysis of carbonates in different size fractions and magnetic susceptibility reveal that calcite is a sensitive index of summer monsoon.The chemical analysis of carbonates and calcite from an 8.1 Ma loess-red clay sequence at Chaona on the Chinese central Loess Plateau shows that the evolution of the Asian summer monsoon experienced four stages,namely 8.1-5.5 Ma,5.5-2.8 Ma,2.8-1.5 Ma and 1.5-0 Ma,with increasing intensification and fluctuation,suggesting a possible combining impacts of uplift of the Tibetan Plateau and global changes on the Asian summer monsoon.

  20. An 8.1Ma calcite record of Asian summer monsoon evolution on the Chinese central Loess Plateau

    Institute of Scientific and Technical Information of China (English)

    2007-01-01

    Carbonates in loess-red clay sequences consist mainly of calcite and dolomite. The EDTA analysis of carbonates in different size fractions and magnetic susceptibility reveal that calcite is a sensitive index of summer monsoon. The chemical analysis of carbonates and calcite from an 8.1 Ma loess-red clay sequence at Chaona on the Chinese central Loess Plateau shows that the evolution of the Asian summer monsoon experienced four stages, namely 8.1―5.5 Ma, 5.5―2.8 Ma, 2.8―1.5 Ma and 1.5―0 Ma, with increasing intensification and fluctuation, suggesting a possible combining impacts of uplift of the Tibetan Plateau and global changes on the Asian summer monsoon.

  1. Diversidad genética en el patosistema maíz-fusarium en el Altiplano de México.

    OpenAIRE

    Briones Reyes, Dolores

    2014-01-01

    Las variantes de maíz (Zea mays L.) nativas (criollos) preservadas por los agricultores a través de generaciones, constituyen más de 80% del área sembrada con maíz en México; la pudrición de mazorca por Fusarium spp. provoca pérdidas de hasta 30%. El estudio de las poblaciones de maíz y sus patógenos como patosistema tiene sentido, pues en la variación genética del maíz nativo se puede encontrar resistencia/tolerancia a enfermedades; el conocimiento de la estructura de las poblaciones de maíz...

  2. Rock et cinéma : quelques éléments sur une relation durable

    OpenAIRE

    ribac, françois

    2006-01-01

    Générique d’ouverture Le numéro de Volume ! que vous allez lire est consacré aux relations entre le rock et le cinéma. Il est publié au moment où s’ouvre la deuxième édition du Festival Paris-Cinéma. Celui-ci comprend un cycle « rock et cinéma » présenté au cinéma l’Entrepôt, à Paris, du 30 juin au 13 juillet 2004. Si l’on cherche à établir des relations entre les mondes du rock et ceux du cinéma, en voici une première illustration, puisque ce numéro est en effet coproduit par un festival de ...

  3. A comparative study of the corrosion resistance of incoloy MA 956 and PM 2000 superalloys

    Directory of Open Access Journals (Sweden)

    Maysa Terada

    2010-12-01

    Full Text Available Austenitic stainless steels, titanium and cobalt alloys are widely used as biomaterials. However, new medical devices require innovative materials with specific properties, depending on their application. The magnetic properties are among the properties of interest for some biomedical applications. However, due to the interaction of magnetic materials with Magnetic Resonance Image equipments they might used only as not fixed implants or for medical devices. The ferromagnetic superalloys, Incoloy MA 956 and PM 2000, produced by mechanical alloying, have similar chemical composition, high corrosion resistance and are used in high temperature applications. In this study, the corrosion resistance of these two ferritic superalloys was compared in a phosphate buffer solution. The electrochemical results showed that both superalloys are passive in this solution and the PM 2000 present a more protective passive film on it associated to higher impedances than the MA 956.

  4. Le schéma: un écrit de savoir?

    OpenAIRE

    Laparra, Marceline; Margolinas, Claire

    2009-01-01

    Dans cet article, nous nous intéressons au schéma, dans le cadre de la résolution de problèmes arithmétiques au début de l'école primaire (classe de C.P.). Ainsi, notre propos se situe à la fois dans le cadre d'une réflexion sur le schéma comme écrit de savoir, mais aussi dans le cadre d'une réflexion sur la résolution des problèmes arithmétiques. Les " écrits de savoir " auxquels nous allons nous intéresser ici présentent une double caractéristique : - Ils ne donnent pas à lire un discours s...

  5. Poétique du film. Textes des formalistes russes sur le cinéma.

    Directory of Open Access Journals (Sweden)

    Galina Subbotina

    2009-10-01

    Full Text Available Dans le domaine littéraire, l’apport des formalistes russes de Moscou et de Petrograd (1915-1930 est unanimement reconnu. On sait moins qu’ils se sont très tôt intéressés au cinéma. La présente édition s’organise autour de Poétique du film, l’ouvrage collectif des formalistes publié en 1927 à Leningrad. Ce texte, devenu un classique de la théorie du cinéma dans plusieurs pays, demeurait inédit en français. La traduction en est signée Valérie Posener, Régis Gayraud et Jean-Christophe Peuch. L...

  6. Towards a 100mA Superconducting RF Photoinjector for BERLinPro

    Energy Technology Data Exchange (ETDEWEB)

    Neumann, Axel; Anders, W; Burrill, Andrew; Jankowiak, Andreas; Kamps, T; Knobloch, Jens; Kugeler, Oliver; Lauinger, P; Matveenko, A N; Schmeisser, M; Volker, J; Ciovati, Gianluigi; Kneisel, Peter; Nietubyc, R; Schubert, S G; Smedley, John; Sekutowicz, Jacek; Volkov, V; Will, I; Zaplatin, Evgeny

    2013-09-01

    For BERLinPro, a 100 mA CW-driven SRF energy recovery linac demonstrator facility, HZB needs to develop a photo-injector superconducting cavity which delivers a at least 1mm*mr emittance beam at high average current. To address these challenges of producing a high peak brightness beam at high repetition rate, at first HZB tested a fully superconducting injector with a lead cathode*,followed now by the design of a SC cavity allowing operation up to 4 mA using CW-modified TTF-III couplers and inserting a normal conducting high quantum efficiency cathode using the HZDR-style insert scheme. This talk will present the latest results and an overview of the measurements with the lead cathode cavity and will describe the design and optimization process, the first production results of the current design and an outlook to the further development steps towards the full power version.

  7. A correlation between southern and northern hemispheres during the last 0.6 Ma

    Institute of Scientific and Technical Information of China (English)

    刘东生; 安芷生; 陈明扬; 孙东怀

    1996-01-01

    A comparison of climate records between Chinese Loess Plateau which shows a strengthening of summer monsoon in the last 0.6 Ma and a strengthening of Asia summer monsoon during 35-25 and 4-2.5ka B.P. intervals, and the Australian records which show a strengthening of aridity or desertification suggest that the Australian high leading to the desertification strengthened the Asia summer monsoon in the past through the cross-equator circulation. The synchronous variation in the Holocene Optimum as indicated by Asia and Australia climate records, on the other hand, suggests that the cross-equator East Asia winter monsoon circulation related to the Mongolia high might have influenced the Australia summer monsoon. The interaction of the monsoon climate between southern and northern hemispheres through cross-equator circulation probably started to be obvious since 0.6 Ma B. P.

  8. Demanda de tortilla de maíz en México, 1996-2008.

    OpenAIRE

    Retes Mantilla, Rogel Fernando

    2011-01-01

    La tortilla de maíz (Zea mays L.) es un alimento fundamental en la dieta de los mexicanos ya que representa el 38.8 % de las proteínas, 45.2 % de las calorías y 49.1 % del calcio de su ingesta diaria. Sin embargo, su demanda disminuyó 36.7 % de 1996 a 2008. Por lo que, el presente trabajo tuvo como objetivo identificar los principales factores económicos que determinan el comportamiento de la demanda de tortilla de maíz en México por estratos de ingreso y medir el orden de magnitud en que dic...

  9. MaMiCo: Software design for parallel molecular-continuum flow simulations

    KAUST Repository

    Neumann, Philipp

    2015-11-19

    The macro-micro-coupling tool (MaMiCo) was developed to ease the development of and modularize molecular-continuum simulations, retaining sequential and parallel performance. We demonstrate the functionality and performance of MaMiCo by coupling the spatially adaptive Lattice Boltzmann framework waLBerla with four molecular dynamics (MD) codes: the light-weight Lennard-Jones-based implementation SimpleMD, the node-level optimized software ls1 mardyn, and the community codes ESPResSo and LAMMPS. We detail interface implementations to connect each solver with MaMiCo. The coupling for each waLBerla-MD setup is validated in three-dimensional channel flow simulations which are solved by means of a state-based coupling method. We provide sequential and strong scaling measurements for the four molecular-continuum simulations. The overhead of MaMiCo is found to come at 10%-20% of the total (MD) runtime. The measurements further show that scalability of the hybrid simulations is reached on up to 500 Intel SandyBridge, and more than 1000 AMD Bulldozer compute cores. Program summary: Program title: MaMiCo. Catalogue identifier: AEYW_v1_0. Program summary URL: http://cpc.cs.qub.ac.uk/summaries/AEYW_v1_0.html Program obtainable from: CPC Program Library, Queen\\'s University, Belfast, N. Ireland. Licensing provisions: BSD License. No. of lines in distributed program, including test data, etc.: 67905. No. of bytes in distributed program, including test data, etc.: 1757334. Distribution format: tar.gz. Programming language: C, C++II. Computer: Standard PCs, compute clusters. Operating system: Unix/Linux. RAM: Test cases consume ca. 30-50 MB. Classification: 7.7. External routines: Scons (http:www.scons.org), ESPResSo, LAMMPS, ls1 mardyn, waLBerla. Nature of problem: Coupled molecular-continuum simulation for multi-resolution fluid dynamics: parts of the domain are resolved by molecular dynamics whereas large parts are covered by a CFD solver, e.g. a lattice Boltzmann automaton

  10. Produção de vinagre de maçã em biorreator Airlift

    OpenAIRE

    Pedroso, Paula Regina Ferraz

    2003-01-01

    Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro Tecnológico. Programa de Pós-Graduação em Engenharia Química. O estado de Santa Catarina é o maior produtor de maçã do país. Para aproveitar esse potencial foi proposto neste trabalho a utilização de um biorreator do tipo airlift de circulação externa para a produção de vinagre de maçã. Trata-se de uma aplicação inovadora que apresentou vantagens quando comparada ao processo clássico de produção de vinagre, especialmen...

  11. Ekonomiczne aspekty Małych Elektrowni Wodnych - wyszukiwanie optymalnych lokalizacji pod budowę MEW

    OpenAIRE

    2013-01-01

    W związku z dynamicznym wzrostem zapotrzebowania na energie elektryczną stale rozwijane są alternatywne źródła jej pozyskiwania. W niniejszym artykule autor koncentruje się na małych elektrowniach wodnych ze względu na ich niewykorzystywany potencjał w Polsce. Przeważający nizinny charakter ukształtowania terenu nie sprzyja budowaniu elektrowni na rzekach górskich, jednak wciąż występują tu niewykorzystywane na potrzeby energetyki rzeki nizinne, na których można zainstalować tzw. małe elek...

  12. Analyse de la présidence de Ma Ying-jeou à mi-mandat

    OpenAIRE

    Muyard, Frank

    2011-01-01

    Depuis son élection comme président de Taiwan en 2008, Ma Ying-jeou s’est engagé dans une politique active de rapprochement avec la Chine, conduisant à la signature d’une série d’accords économiques et commerciaux qui ont normalisé et libéralisé les relations économiques inter-détroit. Mais la manière avec laquelle ce rapprochement est mené, combinée à la crise économique qui a frappé Taiwan pendant l’essentiel des deux premières années du mandat de Ma, et une accumulation de faux pas et de g...

  13. Images de femmes dans le cinéma de la Nouvelle Vague

    OpenAIRE

    Sellier, Geneviève

    2006-01-01

    L’émergence de la Nouvelle Vague au tournant des années 1960 peut se lire comme la revendication d’une posture créatrice relevant de la culture d’élite, dans un medium jusque là éminemment populaire, le cinéma. S’inscrivant dans une tradition culturelle particulièrement forte en France, ce nouveau cinéma va se conjuguer quasi-exclusivement au masculin singulier, et les figures féminines qu’il crée oscillent entre la prise en compte de l’émancipation des femmes réelles et des fantasmes romanti...

  14. Red de valor para maíz con alta calidad de proteína.

    OpenAIRE

    Domínguez Mercado, Claudia Alejandra

    2012-01-01

    En México el retardo en el crecimiento (RC) afecta a más del 15% de los niños menores de cinco años, consecuencia de la desnutrición o malnutrición en niños y madres gestantes y lactantes. El maíz es el cereal más importante a nivel mundial; en México, constituye la base de la alimentación y principal fuente de energía y proteínas. Sin embargo, su proteína es deficiente en aminoácidos esenciales relacionados directamente con el desarrollo físico. El maíz con alta calidad de proteína, descubi...

  15. M&A flows and the foreign exchange markets:practical experiences

    Directory of Open Access Journals (Sweden)

    Martijn A. Schrijvers

    2002-03-01

    Full Text Available The large cross-border Merger and Acquisition flows of the last three years were seen by financial markets as one of the factors behind movements in exchange rates. However, the extent to which an M&A-transaction actually leads to a foreignexchange transaction is dependent on the financing and transaction techniques used and is difficult to measure. In this article, we analyse which considerations underlie the decisions of corporate Treasurers regarding the financing of take-overs and the techniques to be used by forex transactions. We investigate the effect Treasurers believe M&A transactions have on exchange rates and examine whether different techniques make for different effects. The information was obtained through interviews with Treasurers of multinationals conducting large-scale M&A activities.

  16. Structure of Oxide Nanoparticles in Fe-16Cr MA/ODS Ferritic Steel

    Energy Technology Data Exchange (ETDEWEB)

    Hsiung, L; Fluss, M; Kimura, A

    2010-04-06

    Oxide nanoparticles in Fe-16Cr ODS ferritic steel fabricated by mechanical alloying (MA) method have been examined using high-resolution transmission electron microscopy (HRTEM) techniques. A partial crystallization of oxide nanoparticles was frequently observed in as-fabricated ODS steel. The crystal structure of crystalline oxide particles is identified to be mainly Y{sub 4}Al{sub 2}O{sub 9} (YAM) with a monoclinic structure. Large nanoparticles with a diameter larger than 20 nm tend to be incoherent and have a nearly spherical shape, whereas small nanoparticles with a diameter smaller than 10 nm tend to be coherent or semi-coherent and have faceted boundaries. The oxide nanoparticles become fully crystallized after prolonged annealing at 900 C. These results lead us to propose a three-stage formation mechanism of oxide nanoparticles in MA/ODS steels.

  17. Biotransformation of Indole to 3-Methylindole by Lysinibacillus xylanilyticus Strain MA

    Directory of Open Access Journals (Sweden)

    Pankaj Kumar Arora

    2015-01-01

    Full Text Available An indole-biotransforming strain MA was identified as Lysinibacillus xylanilyticus on the basis of the 16S rRNA gene sequencing. It transforms indole completely from the broth culture in the presence of an additional carbon source (i.e., sodium succinate. Gas-chromatography-mass spectrometry identified indole-3-acetamide, indole-3-acetic acid, and 3-methylindole as transformation products. Tryptophan-2-monooxygenase activity was detected in the crude extracts of indole-induced cells of strain MA, which confirms the formation of indole-3-acetamide from tryptophan in the degradation pathway of indole. On the basis of identified metabolites and enzyme assay, we have proposed a new transformation pathway for indole degradation. Indole was first transformed to indole-3-acetamide via tryptophan. Indole-3-acetamide was then transformed to indole-3-acetic acid that was decarboxylated to 3-methylindole. This is the first report of a 3-methylindole synthesis via the degradation pathway of indole.

  18. "Ma vannun tema niuete kui paleuse nimel ..." : [luuletused] / tlk. Andres Ehin, tlk. Ly Seppel

    Index Scriptorium Estoniae

    2004-01-01

    Sisu: "Ma vannun tema niuete kui paleuse nimel ..." ; "Ta on nagu kuu, kelle kuma kõik kummuli kukutab ..." ; "Kuu südaöösel ennustab me jäävat lahkujääma ..." ; "Ei hinda naisterahvas kasinuse mulli ..." ; "Ta nõtket kaela kutsun ligemale ..." ; "Meid ühte heitma tõmbab armuköis ..." ; "Meil kahel pole mõtet lahku minna ..." ; "Ei kuuga saa võrrelda sind, sest et kuu läheb looja ..." ; "Allah ise su ilude hoob on ja kang ..." ; "Kui meesterahvale läeb korda meesterahvas ..." ; "Ja kuis ka kiremöll tal südames ei hulla ..." ; "Teie jaoks ei ole minu võlurohke kallike ..." ; "Oli see vast poisike, nägu ilu täis ..." ; "Aeg tagasi kalli las toob, et mind suisa salvata ...". Tundmatute autorite kirjutatud luuletused jutukogust "1001 ööd" (9. - 10. saj)

  19. The LENS 7 MeV, 10 mA Proton Linac

    CERN Document Server

    Derenchuk, Vladimir Peter; Bogdanov, Alexander; Jones, William P; Rinckel, Thomas; Solberg, Keith

    2005-01-01

    The Indiana University Cyclotron Facility (IUCF) has constructed and placed in operation a Low Energy Neutron Source (LENS) using a 10 mA, 7 MeV proton beam incident on a beryllium target. The proton delivery system (PDS) consists of a 25 keV proton injector, an AccSys Technology, Inc. PL7 Linac* and a beam transport line with non-linear beam spreading.** The accelerator and beamline equipment used in this construction are refurbished and upgraded components from the IUCF CIS/Cooler synchrotron*** facility. After commissioning the beam current at 7 MeV will be 10 mA with a pulse width of up to 300 μs and > 1% duty factor. The PDS was constructed and commissioning started in 2004. First operating results will be described.

  20. On Larkin-Imry-Ma State of 3He-A in Aerogel

    CERN Document Server

    Volovik, G E

    2007-01-01

    Superfluid 3He-A shares the properties of spin nematic and chiral orbital ferromagnet. Its order parameter is characterized by two vectors d and l. This doubly anisotropic superfluid, when it is confined in aerogel, represents the most interesting example of a system with continuous symmetry in the presence of random anisotropy disorder. We discuss the Larkin-Imry-Ma state, which is characterized by the short-range orientational order of the vector l, while the long-range orientational order is destroyed by the collective action of the randomly oriented aerogel strings. On the other hand, sufficiently large regular anisotropy produced either by the deformation of the aerogel or by applied superflow destroys the Larkin-Imry-Ma effect leading to the uniform orientation of the vector l. This interplay of regular and random anisotropy allows us to study many different effects.