Sample records for lytton albion caspar

  1. Lytton Strachey, a Rebellious Man of Peculiarity: A Review of Holroyd’s Lytton Strachey: The New Biography

    Directory of Open Access Journals (Sweden)

    Qinchao Xu


    Full Text Available Lytton Strachey: The New Biography is an important biography by Michael Holroyd, portraying the extraordinary life of Lytton Strachey, who is also a biographer, in detail. Based on reading the text of Lytton Strachey: The New Biography, this paper analyzes Lytton Strachey’s most distinct character - rebel combined with the social background and the theory of “the New Biography” in three aspects. First, Strachey’s rebellious character in his daily life is analyzed. His beating falsetto, ironic tone and ambiguous silence make him mysterious; his unique dressing style makes him different in the Victorian Age when people tended to wear similar clothes with others in dark suits; and at this time people were all optimistic because of their powerful country while Strachey was always surrounded by a mysterious pessimistic air. Second, Strachey’s view of love is analyzed. He had a strong tendency of homosexual and most of his lovers in his life were males. While, in the Victorian Age, homosexual was illegal. Under the pressure of morality and law, Strachey still followed his heart and fell in love with his boys. His life interprets what love really is — his love is a kind of humanistic love, rather than simple lust. Third, this paper analyzes Strachey’s feminist and religious view. He was one of the supporters and participants of the feminist movement in the 19th century. In the society which was dominated by males, Strachey realized that human are born equally. Therefore, he started to fight for the females’ rights. In addition, in order to think independently, Strachey did not follow the crowds blindly to believe in God.

  2. History of the Trenton Albion-Scipio trend of Michigan

    Energy Technology Data Exchange (ETDEWEB)

    Beghini, V G; Conroy, T R


    This discussion of the history of the Trenton Albion-Scipio trend in Michigan includes the location and development history, geology and reservoir characteristics, drilling and completion methods, production and history of both the Albion and Scipio Fields, production operation, and workover procedure. Maps, illustrations, and graphs of the topics discussed are included. The largest drilling problem encountered was lost circulation causing several blowouts, 2 of which resulted in spectacular fires. Production problems include paraffin deposition, corrosion and brine disposal. Well workovers have been performed in an attempt to correct one or more of 3 problems--high gas- oil ratio, high water cut, and low capacity.

  3. Lytton Strachey : l’historien intime de deux reines Lytton Strachey’s Intimate Biographies of Two Queens

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    Jeannine Hayat


    Full Text Available The British writer Lytton Strachey (1880-1932 wrote biographies of the two most eminent Queens of England: Queen Victoria (1921 and Elizabeth and Essex (1928. The two books made him a very famous historian. However, he would personally have preferred to be admired for his poetry or his plays, for he was a very gifted literary author. Nevertheless many of Strachey’s readers have appreciated his conception of biography, as a means of personal confession while studying the destiny of a public figure. Indeed the Stracheyan way of life, free from Victorian moral standards and guided by the rules of the Bloomsbury group, inspired his story of Victoria and Elizabeth. Both Queens at the end of their lives and at the height of their power carried on strange love affairs: Victoria with her Scottish gillie and Elizabeth with the Earl of Essex, thirty years her younger. In fact, both romances subtly reflect Strachey’s own love affairs. He was himself engaged in a kind of common life with Dora Carrington— the painter, thirteen years younger than him, with whom he was not sexually involved— while he engaged in numerous homosexual love affairs.

  4. Results from the UK 3rd generation programme: Albion (United States)

    McEwen, R. K.; Axcell, C.; Knowles, P.; Hoade, K. P.; Wilson, M.; Dennis, P. N. J.; Backhouse, P.; Gordon, N. T.


    Following the development of 1st Generation systems in the 1970s, thermal imaging has been in service with the UK armed forces for over 25 years and has proven itself to be a battle winning technology. More recently the wider accessibility to similar technologies within opposing forces has reduced the military advantage provided by these 1st Generation systems and a clear requirement has been identified by the UK MOD for thermal imaging sensors providing increased detection, recognition and identification (DRI) ranges together with a simplified logistical deployment burden and reduced through-life costs. In late 2005, the UK MOD initiated a programme known as "Albion" to develop high performance 3rd Generation single waveband infrared detectors to meet this requirement. At the same time, under a separate programme supporting higher risk technology, a dual waveband infrared detector was also developed. The development phase of the Albion programme has now been completed and prototype detectors are now available and have been integrated into demonstration thermal imaging cameras. The Albion programme has now progressed into the second phase, incorporating both single and dual waveband devices, focussing on low rate initial production (LRIP) and qualification of the devices for military applications. All of the detectors have been fabricated using cadmium mercury telluride material (CMT), grown by metal organic vapour phase epitaxy (MOVPE) on low cost, gallium arsenide (GaAs) substrates and bump bonded to the silicon read out circuit (ROIC). This paper discusses the design features of the 3rd Generation detectors developed in the UK together with the results obtained from the prototype devices both in the laboratory and when integrated into field deployable thermal imaging cameras.

  5. CASPAR - Nuclear Astrophysics Underground (United States)

    Senarath, Chamaka; Caspar Collaboration


    The CASPAR mainly focuses on Stellar Nucleosynthesis, its impact on the production of heavy elements and study the strength of stellar neutron sources that propels the s-process, 13C(α,n)16O and 22Ne(α,n)25Mg. Currently, implementation of a 1MV fully refurbished Van de Graaff accelerator that can provide a high intensity Î+/- beam, is being done at the Sanford Underground Research Facility (SURF). The accelerator is built among a collaboration of South Dakota School of Mines and Technology, University of Notre Dame and Colorado School of Mines. It is understood that cosmic ray neutron background radiation hampers experimental Nucleosynthesis studies, hence the need to go underground in search for a neutron free environment, to study these reactions at low energies is evident. The first beam was produced in the middle of summer 2017. The entire accelerator will be run before the end of this year. A detailed overview of goals of CASPAR will be presented. NFS Grant-1615197.

  6. Chemical and biological characteristics of Albion reef in the South ...

    African Journals Online (AJOL)

    The role of heterotrophic bacteria, pico-cyanobacteria and benthic cyanobacterial mats was assessed in the cycling of organic carbon and nitrogen in the Albion lagoon, Mauritius. Surveys and sampling for biological and chemical parameters were undertaken at three locations along one northern (T1) and one southern ...

  7. Caspar Wessel. On the Analytical Representation of Direction

    DEFF Research Database (Denmark)

    This book contains the first complete English translation of Caspar Wessel's paper from 1797 "On the Analytical Representation of Direction". The paper has become famous because it gives the first geometric interpretation of the complex numbers. As the complete translation will show, it is also...... remarkable for the analytical representation of directions (vectors) in space and the elegant analytic solution of plane and spherical polygons. Wessel's essay is prefaced by two historical papers on the person Caspar Wessel and his work. They shed much new light on this first important Norwegian...

  8. Anterior cervical decompression and fusion with caspar plate fixation

    International Nuclear Information System (INIS)

    Rehman, L.; Akbar, H.; Das, G.; Hashim, A.S.M.


    Objective: To evaluate the role of anterior cervical decompression and fixation with Caspar plating in cervical spine injury on neurological outcome. Study Design: A case series. Place and Duration of Study: Department of Neurosurgery, Jinnah Postgraduate Medical Centre, Karachi, from July 2008 to March 2011. Methodology: Thirty patients admitted with cervical spine injuries were inducted in the study. All cases were evaluated for their clinical features, level of injury and degree of neurological injury was assessed using Frankel grading. Pre and postoperative record with X-rays and MRI were maintained. Cervical traction was applied to patients with sub-luxation. All patients underwent anterior cervical decompression, fusion and Caspar plate fixation. The follow-up period was 6 months with clinical and radiological assessment. Results: Among 30 patients, 24 (80%) were males and 6 (20%) were females. Age ranged from 15 to 55 years. Causes of injury were road traffic accident (n = 20), fall (n = 8) and assault (n = 2). Commonest mode of injury was road traffic accident (66.6%). Postoperative follow-up showed that pain and neurological deficit were improved in 21 patients. There was no improvement in 7 patients, one patient deteriorated and one expired. All patients developed pain at donor site. Conclusion: Anterior decompression, fusion and fixation with Caspar plate is an effective method with good neurological and radiological outcome. However, it is associated with pain at donor site. (author)

  9. A Lady 'in Proper Proportions'? Feminism, Lytton Strachey, and Florence Nightingale's Reputation, 1918-39. (United States)

    Southern, James


    Lytton Strachey's Eminent Victorians has long been regarded as a watershed in attitudes to Victorian culture, widely seen as having instigated a revolutionary backlash against the values and heroes of the Victorian era in England. Its impact, however, on the reputations of his four subjects-Thomas Arnold, General Gordon, Cardinal Manning and Florence Nightingale-has been subjected to surprisingly little scholarly attention. Drawing on the work of gender historians, this article reassesses Strachey's effect on the reputation of Nightingale, using biographies and contemporary reviews of Eminent Victorians. It argues that, far from 'debunking' the famous nurse as is generally assumed, Strachey in many ways enhanced her reputation and rendered her a plausible icon for English feminists of the 1920s and 1930s. © The Author [2016]. Published by Oxford University Press. All rights reserved. For Permissions, please email:

  10. Sediment transport and storage in North Fork Caspar Creek, Mendocino County, California: water years 1980-1988 (United States)

    Michael Brent Napolitano


    Abstract - The old-growth redwood forest of North Fork Caspar Creek was clear-cut between 1864 and 1904. Previous research on logging-related changes in suspended sediment and streamflow would suggest that North Fork Caspar Creek has recovered from historical logging (Rice et al., 1979; Ziemer, 1981); research on the influence of large woody debris (LWD) on channel...

  11. Albion's fatal tree . Crime and society in eighteenth-century England

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    Rita de Cássia Germano


    Full Text Available Hay, Douglas (org. . Albion's fatal tree . Crime and society in eighteenth-century England . New York, Pantheon Books, 1975, 353 p ., il. , mapas. (primeiro parágrafo do texto A obra coletiva Albion's Fatal Tree. Crime and Society in Eighteenth-Century England, tem como preocupação fundamental a história social da Inglaterra no séc. XVIII, localizando as interrelações entre Lei, ideologia e realidade social, mais a definição de crime na época; estudam os Autores a própria criminalidade, as ofensas à propriedade, os criminosos e os mitos populares sobre eles. Se por um lado parece existir uma multiplicação do "crime" (as estatísticas não são claras a respeito, por outro lado a questão não parece ser o aumento da incidência do "crime", e sim a sua constante redefinição por parte de uma oligarquia consciente de suas propriedades. Quando pressente no recrudescimento dos atentados, multiplicam também os estatutos, passando a punir até com a pena de morte atividades até então consideradas veniais ou inocentes, como o roubo de lenha, a caça em propriedade alheia, ou cartas anônimas de tom ameaçador. A oligarquia dominante, cujo valor supremo é a propriedade, encontra seu embasamento visível e material sobretudo na ideologia e na prática da Lei. A "Tyburn Tree", como bem compreendeu William Blake, encontrava-se no centro desta ideologia, e seus rituais estavam também no cerne da cultura popular (pag. 13 .

  12. Large woody debris budgets in the Caspar Creek Experimental Watersheds (United States)

    Sue Hilton


    Monitoring of large woody debris (LWD) in the two mainstem channels of the Caspar Creek Experimental Watersheds since 1998, combined with older data from other work in the watersheds, gives estimates of channel wood input rates, survival, and outputs in intermediate-sized channels in coastal redwood forests. Input rates from standing trees for the two reaches over a 15...

  13. Road construction on Caspar Creek watersheds --- 10-year report on impact (United States)

    J. S. Krammes; David M. Burns


    In 1960, Federal and State agencies jointly started a long-term study of the effects of logging and road building on streamflow, sedimentation, aquatic habitat, and fish populations on two watersheds of Caspar Creek, in northern California. The experimental watersheds are the North and South Forks of the Creek. The data being collected consist of continuous streamflow...

  14. Channel incision and suspended sediment delivery at Caspar Creek, Mendocino County, California (United States)

    Nicholas J. Dewey; Thomas E. Lisle; Leslie M. Reid


    Tributary and headwater valleys in the Caspar Creek watershed,in coastal Mendocino County, California,show signs of incision along much of their lengths.An episode of incision followed initial-entry logging which took place between 1860 and 1906. Another episode of incision cut into skid-trails created for second-entry logging in the 1970's.

  15. Caspar Paludan-Müller - Zur frühen Ranke-Rezeption in Dänemark

    DEFF Research Database (Denmark)

    Møller, Jes Fabricius


    Den danske reception af Leopold von Rankes værker og historismen skete i overvejende grad gennem Caspar Paludan-Müller, der også anvendte de kildekritiske principper, der hørte til Rankes og Niebuhrs historisme. Historismen og dermed også Paludan-Müllers verdensbillede blev udsat for et stadig st...

  16. Effects of timber harvest on aquatic vertebrates and habitat in the North Fork Caspar Creek (United States)

    Rodney J. Nakamoto


    I examined the relationships between timber harvest, creek habitat, and vertebrate populations in the North and South forks of Caspar Creek. Habitat inventories suggested pool availability increased after the onset of timber harvest activities. Increased large woody debris in the channel was associated with an increase in the frequency of blowdown in the riparian...

  17. [Surgeon and eye doctor Caspar Stromayr and the ophthalmological illustrations in his "Practica copiosa" (1559)]. (United States)

    Nover, A; Kümmel, W F


    In 1559 Caspar Stromayr wrote a richly illustrated book about hernias and their treatment. The manuscript also includes 3 chapters of a book on ophthalmological diseases which, however, was never published. In addition, it contains 6 separate watercolor illustrations of eye diseases, though without any explanatory texts. The authors attempt to interpret these first colored pictures of eye diseases.

  18. A watershed's response to logging and roads: South Fork of Caspar Creek, California, 1967-1976 (United States)

    Raymond M. Rice; Forest B. Tilley; Patricia A. Datzman


    The effect of logging and roadbuilding on erosion and sedimentation are analyzed by comparing the North Fork and South Fork of Caspar Creek, in northern California. Increased sediment production during the 4 years after road construction, was 326 cu yd/sq mi/yr—80 percent greater than that predicted by the predisturbance regression analysis. The average...

  19. Effects of forest harvest on stream-water quality and nitrogen cycling in the Caspar Creek watershed (United States)

    Randy A. Dahlgren


    The effects of forest harvest on stream-water quality and nitrogen cycling were examined for a redwood/Douglas-fir ecosystem in the North Fork, Caspar Creek experimental watershed in northern California. Stream-water samples were collected from treated (e.g., clearcut) and reference (e.g., noncut) watersheds, and from various locations downstream from the treated...

  20. Imitação musical segundo o Kantor Caspar Ruetz (1754

    Directory of Open Access Journals (Sweden)

    Mônica Lucas


    Full Text Available The poetic principle that all arts are reducible to a unified principle (imitation of nature was largely spread in 18th Century Germany, especially by the influential Les Beaux Arts Réduits a un Même Principe (The Fine Arts reduced to a same principle, by Charles Batteux (1746. However, in the Lutheran world, this ideal was accommodated to the Augustinian musical thought, and the resulting synthesis provided the basis for the Romantic music conception. This fusion of ideas is clearly perceptible in the comment to Batteux’s work (1754 published by the Kantor Caspar Ruetz (1708-1755.

  1. Caspar Paludan-Müller - Zur frühen Ranke-Rezeption in Dänemark


    Møller, Jes Fabricius


    Den danske reception af Leopold von Rankes værker og historismen skete i overvejende grad gennem Caspar Paludan-Müller, der også anvendte de kildekritiske principper, der hørte til Rankes og Niebuhrs historisme. Historismen og dermed også Paludan-Müllers verdensbillede blev udsat for et stadig større pres i løbet af det 19. århundrede. og især Kristian Erslevs kritik af Paludan-Müller skal ses som et udtryk for modernismens og positivismens fremkomst. Erslevs kritik af Paludan-Müller var Ersl...

  2. Evaluating the impacts of logging activities on erosion and suspended sediment transport in the Caspar Creek watersheds (United States)

    Jack Lewis


    Suspended sediment has been sampled at both the North and South Fork weirs of Caspar Creek in northwestern California since 1963, and at 13 tributary locations in the North Fork since 1986. The North Fork gaging station (NFC) was used as a control to evaluate the effects of logging in the South Fork, in the 1970's, on annual sediment loads. In the most...

  3. The CAnadian Surface Prediction ARchive (CaSPAr): A Platform to Enhance Environmental Modelling in Canada and Globally (United States)

    Tolson, B.; Mai, J.; Kornelsen, K. C.; Coulibaly, P. D.; Anctil, F.; Fortin, V.; Leahy, M.; Hall, B.


    Environmental models are tools for the modern society for a wide range of applications such as flood and drought monitoring, carbon storage and release estimates, predictions of power generation amounts, or reservoir management amongst others. Environmental models differ in the types of processes they incorporate, where land surface models focus on the energy, water, and carbon cycle of the land and hydrological models concentrate mainly on the water cycle. All these models, however, have in common that they rely on environmental input data from ground observations such as temperature, precipitation and/or radiation to force the model. If the same model is run in forecast mode, numerical weather predictions (NWPs) are needed to replace these ground observations. Therefore, it is critical that NWP data be available to develop models and validate forecast performance. These data are provided by the Meteorological Service of Canada (MSC) on a daily basis. MSC provides multiple products ranging from large scale global models ( 33km/grid cell) to high resolution pan-Canadian models ( 2.5km/grid cell). Operational products providing forecasts in real-time are made publicly available only at the time of issue through various means with new forecasts issued 2-4 times per day. Unfortunately, long term storage of these data are offline and relatively inaccessible to the research and operational communities. The new Canadian Surface Prediction Archive (CaSPAr) platform is an accessible rolling archive of 10 of MSC's NWP products. The 500TB platform will allow users to extract specific time periods, regions of interest and variables of interest in an easy to access NetCDF format. CaSPAr and community contributed post-processing scripts and tools are being developed such that the users, for example, can interpolate the data due to their needs or auto-generate model forcing files. We will present the CaSPAr platform and provide some insights in the current development of the web

  4. Comparison of the yields of downstream migrant salmonids before and after logging and road construction on the South Fork Caspar Creek, Mendocino County (United States)

    David S. Graves; James W. Burns


    Yields of juvenile steelhead rainbow trout Salmo gairdnerii gairdnerii) and silver salmon (Oncorhynchus kisutch) emigrants were compared in South Fork Caspar Creek, a small coastal stream in Mendocino County, California, before and after construction of a logging road along the stream in the summer of 1967. Numbers, lengths, and age class structures were compared....

  5. MEMBEDAH TEORI SOSIOLOGI: Teori Pertukaran (Exchange Theory George Caspar Homans

    Directory of Open Access Journals (Sweden)

    Wardani Wardani


    Full Text Available This article is aimed at analyzing critically George Caspar Homans’s theory of exchange. The critical analysis that may be called here simply as “maping ideology” embodied in theory is needed to place the theory within the specific social and political condition, intellectual background, school of thought having great influence on it, and so forth, and also to assesses its limitedness as a theoretical frame-work of scientific research to explain complicated social phenomenon or human interaction. Influenced by psychological and economic theories, Homans’s theory of exchange has been intended at the beginning by the author as attack against Marxism domination that addressed criticism to capitalism as macro-structure oppressing the proletariat by the ruling class and against Durkheimian structural functionalism. By addressing the attack against Marxism and because of his intellectual and social background, Homans’s theory then has been regarded as an explanation justifying the existing situation. Being attributed as psychological reductionism, as neglecting the important role of structure, and deterministic are some of the objections addressed to his theory.

  6. [Recurrent depressive disorder in Caspar David Friedrich. A pathographical approach with operationalized diagnosis]. (United States)

    Spitzer, C; Dahlenburg, B; Freyberger, H J


    Caspar David Friedrich (1774 - 1840) is one of the most important German Romantic painters. In his paintings, he prototypically represents the melancholy, which has been mentioned by his contemporaries and later biographers. Art scientists have also referred to his melancholy for the interpretation of his work. From a medical point of view, there are only two pathographies which remain inconclusive. Having applied diagnostic criteria for psychiatric disorders to his letters and publications, to statements of his contemporaries and to his art, we propose that he had suffered from a recurrent major depression which occurred in 1799 for the first time. At least three depressive episodes followed before he was struck by a stroke in 1835. There are epidemiological, psychodynamic and personality-typological reasons supporting our diagnostic assumption. The course of his depression corresponds to phases of reduced creativity, to the chosen techniques and motives. Finally we discuss the implications of our approach for the pathographical method in general.

  7. The Intercontinental Ballistic Missile and Post Cold War Deterrence (United States)


    Bonnetain, Hugues and Philippe Mazzoni. " Histoire De Missiles...Le 1er GMS Du Plateau D’Albion.", " Histoire De Missiles...Le 1er GMS Du Plateau D’Albion,"; Ministère de la Défense

  8. [Health pedagogy instead of consolation. Theological adjustment to illness by Philipp Melanchthon and Caspar Peucer]. (United States)

    Bröer, R; Hofheinz, R


    Subject of this paper is the interpretation of disease as physical evil (malum physicum) by the university professors Philipp Melanchthon (1497-1560) and Caspar Peucer (1525-1602) at Protestant Wittenberg. Melanchthon and Peucer settled the problem of theodicy principally by theological strategies of moralization and compensation. In most cases, therefore, disease resulted from inadequate health behavior, especially drunkenness, furthermore from disdain for medicine and obstruction of divine healing. As a rule, natural factors (e.g. celestial bodies or human affections) only contributed to disease. In general it was caused by free will. In consequence the strategies of depotentiation and functionalization of disease became insignificant resulting in the accentuation of its evil nature. By way of compensation Melanchthon and Peucer stressed the Divine healing of disease. God created the natural remedies and later He created the medical arts by granting heroic virtue to the greatest doctors (Hippocrates, Galen, Avicenna). Moreover the divine Trinity could directly harmonize affections. Thus, God incited a psychosomatical healing within the human organism. As far as physical evil is concerned Lutheran pathology substituted medieval pessimism for therapeutical optimism. Melanchthon and Peucer strived to discipline the patients' behavior and to legitimate the medical arts by God. In this sense their pathology formed part of a program of social and religious stabilization. The academic medicine profited greatly from that program in later years.

  9. The timing of tertiary metamorphism and deformation in the Albion-Raft River-Grouse Creek metamorphic core complex, Utah and Idaho (United States)

    Strickland, A.; Miller, E.L.; Wooden, J.L.


    The Albion-Raft River-Grouse Creek metamorphic core complex of southern Idaho and northern Utah exposes 2.56-Ga orthogneisses and Neoproterozoic metasedimentary rocks that were intruded by 32-25-Ma granitic plutons. Pluton emplacement was contemporaneous with peak metamorphism, ductile thinning of the country rocks, and top-to-thewest, normal-sense shear along the Middle Mountain shear zone. Monazite and zircon from an attenuated stratigraphic section in the Middle Mountain were dated with U-Pb, using a SHRIMP-RG (reverse geometry) ion microprobe. Zircons from the deformed Archean gneiss preserve a crystallization age of 2532 ?? 33 Ma, while monazites range from 32.6 ?? 0.6 to 27.1 ?? 0.6 Ma. In the schist of the Upper Narrows, detrital zircons lack metamorphic overgrowths, and monazites produced discordant U-Pb ages that range from 52.8 ?? 0.6 to 37.5 ?? 0.3 Ma. From the structurally and stratigraphically highest unit sampled, the schist of Stevens Spring, narrow metamorphic rims on detrital zircons yield ages from 140-110 Ma, and monazite grains contained cores that yield an age of 141 ??2 Ma, whereas rims and some whole grains ranged from 35.5 ?? 0.5 to 30.0 ?? 0.4 Ma. A boudinaged pegmatite exposed in Basin Creek is deformed by the Middle Mountains shear zone and yields a monazite age of 27.6 ?? 0.2 Ma. We interpret these data to indicate two periods of monazite and metamorphic zircon growth: a poorly preserved Early Cretaceous period (???140 Ma) that is strongly overprinted by Oligocene metamorphism (???32-27 Ma) related to regional plutonism and extension. ?? 2011 by The University of Chicago.

  10. Syn-extensional plutonism and peak metamorphism in the albion-raft river-grouse creek metamorphic core complex (United States)

    Strickland, A.; Miller, E.L.; Wooden, J.L.; Kozdon, R.; Valley, J.W.


    The Cassia plutonic complex (CPC) is a group of variably deformed, Oligocene granitic plutons exposed in the lower plate of the Albion-Raft River- Grouse Creek (ARG) metamorphic core complex of Idaho and Utah. The plutons range from granodiorite to garnet-bearing, leucogranite, and during intrusion, sillimanite- grade peak metamorphism and ductile attenuation occurred in the country rocks and normal-sense, amphibolite-grade deformation took place along the Middle Mountain shear zone. U-Pb zircon geochronology from three variably deformed plutons exposed in the lower plate of the ARG metamorphic core complex revealed that each zircon is comprised of inherited cores (dominantly late Archean) and Oligocene igneous overgrowths. Within each pluton, a spread of concordant ages from the Oligocene zircon overgrowths is interpreted as zircon recycling within a long-lived magmatic system. The plutons of the CPC have very low negative whole rock ??Nd values of -26 to -35, and initial Sr values of 0.714 to 0.718, consistent with an ancient, crustal source. Oxygen isotope ratios of the Oligocene zircon overgrowths from the CPC have an average ??18O value of 5.40 ?? 0.63 permil (2SD, n = 65) with a slight trend towards higher ??18O values through time. The ??18O values of the inherited cores of the zircons are more variable at 5.93 ?? 1.51 permil (2SD, n = 29). Therefore, we interpret the plutons of the CPC as derived, at least in part, from melting Archean crust based on the isotope geochemistry. In situ partial melting of the exposed Archean basement that was intruded by the Oligocene plutons of the CPC is excluded as the source for the CPC based on field relationships, age and geochemistry. Correlations between Ti and Hf concentrations in zircons from the CPC suggest that the magmatic system may have become hotter (higher Ti concentration in zircon) and less evolved (lower Hf in zircon concentration) through time. Therefore, the CPC represents prolonged or episodic magmatism

  11. (Ridley, 1884) (Phylum: Porifera, Class: Demospongiae)

    African Journals Online (AJOL)

    Abstract—The distribution and abundance of the sponge Spheciospongia vagabunda (Ridley, 1884) was investigated in a shallow lagoon (Albion) of. Mauritius (Western Indian Ocean). Sponge abundance and environmental parameters were assessed. Sponges in Albion lagoon were mostly distributed in the central part of ...

  12. Chemical characterisation of two Australian-grown strawberry varieties by using comprehensive two-dimensional gas chromatography-mass spectrometry. (United States)

    Samykanno, Kavitha; Pang, Edwin; Marriott, Philip J


    The volatile compositions of two strawberry varieties ('Albion' and 'Juliette') grown in Australia were analysed with comprehensive two-dimensional gas chromatography (GC×GC) combined with time-of-flight mass spectrometry (ToFMS). A suitable data processing method was created that should be sufficiently robust to compare sample chromatograms within a harvest season as well as between seasons with relative ease. Ninety-four compounds were tentatively or positively identified between the two varieties of which 20 have apparently not been previously reported to be components of strawberry volatiles. It was determined that Albion and Juliette have comparable total soluble solids content close to 11°Brix. However, since Juliette exhibited a lower titratable acidity content than Albion, it consequently has a slightly larger sugar/acid ratio. The presence of 2,5-dimethyl-4-hydroxy-(2H)-furan-3-one (furaneol) was detected only in Juliette and this variety also had a higher area percentage of 2,5-dimethyl-4-methoxy-(2H)-furan-3-one (mesifuran), according to the sampling protocol. These experimental results offer possible explanations as to why Juliette is perceived to have a sweeter flavour than Albion. Copyright © 2013 Elsevier Ltd. All rights reserved.

  13. "From la Malinche and Menchu to Modern-Day "Mayas": Women Forging Paths through the Maze of Higher Education" (United States)

    Hall, Vickie A.


    "Beneath the rule of men entirely great, the pen is mightier than the sword." Bulwer-Lytton recognized this strength years ago, and its truth continues to ring true in the works of authors: Tzvetan Todorov, Octavio Paz, Carlos Fuentes, Rigoberta Menchu, and Deborah Tannen. Language is a centuries-old weapon wielded in the struggle against…

  14. Water quality of some logged and unlogged California streams (United States)

    Fredric R. Kopperdahl; James W. Burns; Gary E. Smith


    Water quality was monitored in 1968 and 1969 in six coastal streams in northern California, four of which were subjected to logging and/or road building (Bummer Lake Creek, South Fork Yager Creek, Little North Fork Noyo River, and South Fork Caspar Creek), while the others remained undisturbed (Godwood Creek and North Fork Caspar Creek). The purposes of this study were...

  15. Vastuolud annavad märku muutuste vajadusest / Marit Pukk

    Index Scriptorium Estoniae

    Pukk, Marit


    Kiiresti areneva firma struktuur vajab muutmist. Kommenteerivad gasellettevõtete juhid Argo Schneider (OÜ Albion Reisid), Peep Nork (AS Euro Truck Trade Center), Riinu Värk (AS Meditsiinigrupp) ja Tiit Elenurm

  16. The occurrence of psoriatic arthritis in Denmark

    DEFF Research Database (Denmark)

    Pedersen, Ole Birger Vesterager; Svendsen, Anders Jørgen; Ejstrup, Leif


    OBJECTIVE: To apply and compare different classification criteria on a representative nationwide sample of psoriatic arthritis (PsA) twins and to estimate the prevalence and incidence of PsA. METHODS: The study comprised three Danish nationwide twin cohorts. In 1994 37,388 Danish twin individuals...... and in 2002 46,418 twin individuals received a questionnaire including questions on rheumatic diseases. Twins reporting PsA and their co-twins were classified according to the Moll and Wright (M&W) and CASPAR criteria based on interview, clinical examination, and scrutiny of medical records. RESULTS: A total...... of 228 twin individuals reported PsA and 184 (81%) participated in clinical validation. By using the M&W and CASPAR criteria 54 and 50 cases were diagnosed with PsA respectively. The positive predictive value of self-reported PsA was 31%. According to the M&W and CASPAR criteria the prevalence was 0...

  17. Bioinspired Supramolecular Enzymatic Systems (United States)


    in this bistable [2]rotaxane upon exposure to light or molecular oxygen , respectively. 2.11 Solution-Phase Mechanistic Study and Solid-State...Am. Chem. Soc. 2008, 130, 804-805. 6. Dieringer, J. A.; Lettan, R. B., II; Scheidt, K. A.; Van Duyne, R. P. “ Isotope Labeled Single Molecule...Lytton- Jean , A. K. R.; Hurst, S.; Mirkin, C. A. “Silver Nanoparticle Oligonucleotide Conjugates Based on Triple Cyclic Disulfide Moieties,” Nano

  18. Persistence of physics and engineering students via peer mentoring, active learning, and intentional advising (United States)

    McCavit, K.; Zellner, N. E. B.


    Albion College, a private, undergraduate-only, liberal arts college in Michigan, USA, has developed and implemented a low-cost peer-mentoring programme that blends personal and academic support to help students achieve academic success in the introductory courses required for the Physics Major or the Dual-Degree Program in Engineering. This enhanced mentoring programme provides much-needed assistance for undergraduate students to master introductory physics and mathematics coursework, to normalise the struggle of learning hard material, and to accept their identity as physics or engineering students (among other goals). Importantly, this programme has increased retention among entering science, technology, engineering and mathematics students at Albion College as they move through the introductory classes, as shown by a 20% increase in retention from first-semester to third-semester physics courses compared to years when this programme was not in place.

  19. Plaadid / Mart Normet

    Index Scriptorium Estoniae

    Normet, Mart, 1979-


    Uutest heliplaatidest J.M.K.E. "mälestusi Eesti NSV-st", Infadels "We Are Not The Infadels", Babyshambles "Down In Albion", Rigmor Gustafsson "On My Way To You", Mary J. Blige "The Breakthrough", Beck "Guerolito", Scala & Kolacny Brothers "Grenzenlos"

  20. Phyllochron estimation in intercropped strawberry and monocrop systems in a protected environment

    Directory of Open Access Journals (Sweden)

    Heloísa Ferro Constâncio Mendonça


    Full Text Available The phyllochron is defined as the time required for the appearance of successive leaves on a plant; this characterises plant growth, development and adaptation to the environment. To check the growth and adaptation in cultivars of strawberry grown intercropped with fig trees, it was estimated the phyllochron in these production systems and in the monocrop. The experiment was conducted in greenhouses at the University of Passo Fundo (28º15'41'' S, 52º24'45'' W and 709 m from June 8th to September 4th, 2009; this comprised the period of transplant until the 2nd flowering. The cultivars Aromas, Camino Real, Albion, Camarosa and Ventana, which seedlings were originated from the Agrícola LLahuen Nursery in Chile, as well as Festival, Camino Real and Earlibrite, originated from the Viansa S.A. Nursery in Argentina, were grown in white polyethylene bags filled with commercial substrate (Tecnomax® and evaluated. The treatments were arranged in a randomised block design and four replicates were performed. A linear regression was realized between the leaf number (LN in the main crown and the accumulated thermal time (ATT. The phyllochron (degree-day leaf-1 was estimated as the inverse of the angular coefficient of the linear regression. The data were submitted to ANOVA, and when significance was observed, the means were compared using the Tukey test (p < 0.05. The mean and standard deviation of phyllochrons of strawberry cultivars intercropped with fig trees varied from 149.35ºC day leaf-1 ± 31.29 in the Albion cultivar to 86.34ºC day leaf-1 ± 34.74 in the Ventana cultivar. Significant differences were observed among cultivars produced in a soilless environment with higher values recorded for Albion (199.96ºC day leaf-1 ± 29.7, which required more degree-days to produce a leaf, while cv. Ventana (85.76ºC day leaf-1 ± 11.51 exhibited a lower phyllochron mean value. Based on these results, Albion requires more degree-days to issue a leaf as

  1. Nano particles as the primary cause for long-term sunlight suppression at high southern latitudes following the Chicxulub impact - evidence from ejecta deposits in Belize and Mexico

    DEFF Research Database (Denmark)

    Vajda, Vivi; Ocampo, Adriana; Ferrow, Embaie


    deposits occur in Belize and southern Mexico where the so called Albion island spheroid bed is superimposed on the target rock (the Barton Creek Formation). We analysed the spheroid bed via Mössbauer spectroscopy, petrology, XRD, and palynology at several sites ~ 350-500 km distance from the crater centre....... Our results show that the relative concentrations of Fe in nano-phase goethite (α-FeOOH) are very high in the spheroid bed samples from Albion Island (Belize) and from Ramonal South (Mexico), but are low to absent in the spheroid bed at Ramonal North, and in the Cretaceous target rock. Moreover, our......Life on Earth was sharply disrupted 66 Ma ago as an asteroid hit the sea-floor in what is today Yucatan Peninsula, Mexico. Approximately 600 km3 of sedimentary rock were vapourized, ejected into the atmosphere and subsequently deposited globally as an ejecta apron and fallout layer. Proximal ejecta...

  2. Austrian Lives


    Bischof, Günter; Plasser, Fritz; Maltschnig, Eva


    Writing biographies for a long time had been a male hegemonic project. Ever since Plutarch and Sueton composed their vitae of the greats of classical antiquity, to the medieval obsession with the hagiographies of holy men (and a few women) and saints, Vasari's lives of great Renaissance artists, down to the French encyclopedists, Dr. Johnson and Lytton Strachey, as well as Ranke and Droysen the genre of biographical writing has become increasingly more refined. In the twentieth century male p...

  3. Contextualizing African American Collegians' Experiences of Racial Desegregation in Midwestern Private Colleges, 1945-1965 (United States)

    Stewart, Dafina-Lazarus


    A group of private liberal arts colleges in Ohio, Michigan, and Indiana, formed a voluntary association called the Great Lakes Colleges Association (GLCA) in 1962 based on their self-perceived shared interests and missions. These institutions included Albion College, Antioch College, Denison University, DePauw University, Earlham College, Hope…

  4. En gave til skolernes litteraturundervisning

    DEFF Research Database (Denmark)

    Larsen, Peter Stein


    Mens Caspar Erics debutdigtsamling, " 7/ 11", fra sidste år var præget af en stil, hvor der i en hæsblæsende strøm blev refereret til Facebook, You-Tube, iPhone, mp3, Macbook, Twitter og Netflix, frem for at man fik noget at vide om, hvad der rørte sig i ... ......Mens Caspar Erics debutdigtsamling, " 7/ 11", fra sidste år var præget af en stil, hvor der i en hæsblæsende strøm blev refereret til Facebook, You-Tube, iPhone, mp3, Macbook, Twitter og Netflix, frem for at man fik noget at vide om, hvad der rørte sig i ... ...

  5. Web-based diagnosis and therapy of auditory prerequisites for reading and spelling

    Directory of Open Access Journals (Sweden)

    Krammer, Sandra


    Full Text Available Cognitive deficits in auditory or visual processing or in verbal short-term-memory are amongst others risk factors for the development of dyslexia (reading and spelling disability. By early identification and intervention (optimally before school entry, detrimental effects of these cognitive deficits on reading and spelling might be prevented. The goal of the CASPAR-project is to develop and evaluate web-based tools for diagnosis and therapy of cognitive prerequisites for reading and spelling, which are appropriate for kindergarten children. In the first approach CASPAR addresses auditory processing disorders. This article describes a computerized and web-based approach for screening and testing phoneme discrimination and for promoting phoneme discrimination abilities through interactive games in kindergarteners.

  6. Ainusilmi : Imat Suumanni maastikumaalidest / Eduard Parhomenko

    Index Scriptorium Estoniae

    Parhomenko, Eduard, 1966-


    Imat Suumanni näitus "Kusagil Kodavere kandis II" novembris Obu galeriis Tartus. Silmapiirist kunstniku maalidel. Võrdluseks lühidalt Caspar David Friedrichi maastikest, Mark Rothko abstraktsetest maalidest

  7. Computer Programs for Sun and Moon Illuminance with Contingent Tables and Diagrams (United States)


    data provided by the computer routines are also available from the tables and diagrams. Tables required for manual calculation of the Moon’s...8217 Winona MONTANA 104 45 Albion 110 45 Alpine 113 46 Anaconda 114 49 Apgar 104 46 Baker 110 48 Big Sandy 110 46 Big Timber 109 46 Billings 107

  8. From Racism to Hope (United States)

    Longhurst, Jessie


    This article describes the two-day "Healing in Racism" training received by Jessie Longhurst when she was a teenager in her hometown of Albion, Michigan. She accepted an invitation from her father to attend the program, and states that the training gave her a better understanding of what it means to be African American in our country,…

  9. The Morphing of America's Liberal Arts Colleges (United States)

    DiMaria, Frank


    In this article, the author discusses the paper, "Where Are They Now? Revisiting Breneman's Study of Liberal Arts Colleges" by Vicki L. Baker, assistant professor at Albion College and Roger G. Baldwin, professor at University of Michigan. Their paper takes a look back at David W. Breneman's study "Are We Losing Our Liberal Arts Colleges?" and it…

  10. Crescimento do morangueiro: influência da cultivar e da posição da planta no canteiro Strawberry growth: effect of cultivar and plant position in the bed

    Directory of Open Access Journals (Sweden)

    André Samuel Strassburger


    Full Text Available O objetivo deste trabalho foi avaliar o crescimento de cultivares de morangueiro em sistema de cultivo orgânico, observando a influência da posição da planta no canteiro sobre a produção acumulada e a partição de massa seca entre os órgãos aéreos das plantas. O experimento foi realizado na Embrapa Clima Temperado, Estação Experimental Cascata, Pelotas, RS. Os tratamentos constaram da combinação de dois fatores experimentais: cultivar ('Albion', 'Aromas', 'Camarosa' e 'Camino Real' e a posição das plantas no canteiro (Central e Bordadura. O delineamento experimental adotado foi o de blocos completos casualizados com parcelas divididas e quatro repetições. A cultivar 'Camarosa' apresentou maior produção de massa seca dos órgãos aéreos das plantas (62,3; 27,5 e 88,0g planta-1 para folha, coroa e frutos, respectivamente e, juntamente com a 'Aromas', maior produtividade (64,2 e 59,1Mg ha-1, respectivamente. A cultivar 'Aromas' apresentou a maior contribuição proporcional dos frutos para a composição do total de massa seca da planta (60,6% e o maior índice de colheita (88%. A posição das plantas não influenciou o crescimento e a produtividade, indicando ausência de efeito de bordadura para as cultivares 'Albion', 'Aromas', 'Camarosa' e 'Camino Real'.The aim of this research was to evaluate the growth of strawberry cultivars growing in organic crop system observing the influence of plant position in the bed on accumulated dry matter production and its partitioning among the aboveground plant organs. The experiment was conducted in Embrapa Clima Temperado, Estação Experimental Cascata, Pelotas, RS. The treatments were compose by the combination of two experimental factors: cultivar ('Aromas', 'Albion', 'Camarosa' and 'Camino Real' and plant position in the bed (Central and Border. The experimental design used was randomized blocks with split-plots and four replications. 'Camarosa' cultivar presented highest dry mass

  11. Two African Saints in Medieval Germany. (United States)

    Grimm, Reinhold


    The origin and development of two African saints are discussed: Saint Maurice, patron saint of the eastern empire of Otto I; and Caspar, the youngest of the three Magi. Their representation in German art is described and illustrated. (Author/LB)

  12. The Rothko Chapel Paintings and the Urgency of the Transcendent Experience

    NARCIS (Netherlands)

    Stoker, W.


    Since the Romantic period, painters have no longer made use of traditional Christian iconography to express religious transcendence. Taking their cue from Schleiermacher's Reden Über die Religion, painters have sought for new, personal ways to express religious transcendence. One example is Caspar

  13. Production of strawberry cultivars in closed hydroponic systems and coconut fibre substrate

    Directory of Open Access Journals (Sweden)

    Fabio Rodrigues de Miranda

    Full Text Available The objective of this work was to evaluate yield and average fruit weight of strawberry cultivars Albion, Camarosa, Festival and Oso Grande, in two closed hydroponic systems (gutters and grow bags, using coconut fibre as substrate. The experimental design was of randomised blocks, divided into strips, with five replications. The hydroponic systems did not differ significantly as to yield, with advantages, such as savings in water and fertilizer and reduced environmental impact, over open systems. The most productive cultivar was Festival, followed by Oso Grande, with average yields of 6.99 kg m-2 and 5.56 kg m-2 respectively. The cultivars with the greatest fruit weight were Oso Grande and Albion, having averages of 11.8 and 11.1 g respectively, with the former being significantly superior to the latter. The highest yield (7.4 kg m-2 was obtained from the cultivar Festival under the gutter system. The Ibiapaba region has conditions which are favourable to strawberry production in relation to precocity (harvesting starts in the 6th week of growth and production continues throughout the year; however there is a need to test new cultivars and to improve the cultivation techniques with an aim to producing larger-sized fruit.

  14. Relationship between production, nematodes and "redness" in strawberries

    Directory of Open Access Journals (Sweden)

    Paula Nogueira Curi


    Full Text Available ABSTRACT: In recent years "redness" has increasingly appeared in strawberry plants with leaves taking on a reddish color. No causal agent has been associated with plants. Since strawberries presented problems due to the incidence of nematodes, the purpose of this study was to look at the relationship between production, resistance to the Meloidogyne hapla nematode and the "redness" symptom in strawberry cultivars. Two experiments were performed, both with the 'Camino Real', 'Festival', 'Oso Grande', 'Albion' and 'Camarosa' cultivars. The first experiment was performed in the field, where the following were evaluated: strawberry production, fruit quality, macro and micronutrient contents in fruit and leaves, percentage of plant survival, incidence of nematodes, quantity of eggs in the roots and juveniles in the soil, and the incidence of Botrytis cinerea . In the second experiment, the strawberries were transplanted into pots and filled with pinus bark-based commercial substrate. Half the pots were inocculated with Meloidogyne hapla . Cultivars presented differences in fruit production and also in the incidence of "redness". Lowest performance in production was related to the high incidence of the nematode Meloidogyne hapla. 'Oso Grande' and 'Albion' presented nematode-resistant behavior. It was possible find a relationship between the incidence of the Meloidogyne hapla nematode, and the incidence of "redness" only 'Camino Real' cultivar.

  15. 75 FR 51104 - National Register of Historic Places; Notification of Pending Nominations and Related Actions (United States)


    ..., Daglren, Frostown, Mt. Tabor, and Moser Rds, Middletown, 10000575 MINNESOTA Big Stone County St. Pauli... Montgomery County Caspar Getman Farmstead, 1311 Stone Arabia Rd, Stone Arabia, 10000594 New York County Park..., Charlotte, 10000603 Polk County Lynncote, 3318 Lynn Rd, Tryon, 10000604 NORTH DAKOTA Grand Forks County R.S...

  16. Lavater ja Goethe / Linnar Priimägi

    Index Scriptorium Estoniae

    Priimägi, Linnar, 1954-


    Arvustus: Lavateri näoraamat : valgustusajastu pilk inimesele ja kunstile : toetudes Johann Caspar Lavateri menuteosele "Füsiognoomilisi fragmente inimesetundmise ja ligimesearmastuse edendamiseks" (1775-1778) / koostanud, kommenteerinud ja toimetanud Anu Allikvee ja Tiina-Mall Kreem ; fragmentide tõlge: Katrin Kaugver. Tallinn : Eesti Kunstimuuseum, Mikkeli Muuseum ; Tallinna Ülikool, Akadeemiline Raamatukogu. 2015

  17. Physics-based simulations of the impacts forest management practices have on hydrologic response (United States)

    Adrianne Carr; Keith Loague


    The impacts of logging on near-surface hydrologic response at the catchment and watershed scales were examined quantitatively using numerical simulation. The simulations were conducted with the Integrated Hydrology Model (InHM) for the North Fork of Caspar Creek Experimental Watershed, located near Fort Bragg, California. InHM is a comprehensive physics-based...

  18. Online Counseling: A Need for Discovery (United States)

    Mallen, Michael J.; Vogel, David L.


    The rejoinder responds to the four reactions by Jeffrey Barnett, Tai Chang, Delida Sanchez-Page, and Franz Caspar and Thomas Berger in the November 2005 issue of The Counseling Psychologist. In doing so, the authors emphasize the important need for further clarity regarding the effectiveness of online mental and behavioral health services in…

  19. From Theory to Practice: The Powell Doctrine (United States)


    along a common theme. In 1990 Reagan’s Secretary of Defense, Caspar Weinberger, wrote that the “ myths ” about Reagan’s disengagement and lack of...position or congratulated me on getting it.”193 “ Scary ” was Powell’s more frank description of Reagan’s lack of guidance and decision.194 In

  20. Precocious albion: A new interpretation of the British Industrial Revolution


    Kelly, Morgan; Mokyr, Joel; Ó Gráda, Cormac


    Many explanations have been offered for the British Industrial Revolution. This article points to the importance of human capital (broadly defined) and the quality of the British labor force on the eve of the Industrial Revolution. It shows that in terms of both physical quality and mechanical skills, British workers around 1750 were at a much higher level than their continental counterparts. As a result, new inventions—no matter where they originated—were adopted earlier, faster, and on a la...

  1. ウースーンとエニサルモンー ブレイク の 相反する(女)性イメージ について


    渡部, 充; Mitsuru, WATANABE


    Many critics have pointed out Blake's sexism or "anti-feminism,"not only in such a later work as Jerusalem but also in his early songs from Poetical Sketches. Indeed, his writings continue to show strongly antithetical images of female and sexuality. For example, Oothoon in Visions of Daughters of Albion and Enitharmon in Europe stand in such a sharp contrast that it seems almost impossible to contain the both in certain consistent plain of thought. On one hand, sexuality for Blake is a door ...

  2. Kirjandus- ja kultuuritegelased Pärnu Alevi kalmistul / Gerda Kuum

    Index Scriptorium Estoniae

    Kuum, Gerda


    Jutukirjanik Suve Jaan, kodanikunimega Sommer Johann Friedrich (1777-1851); baltisaksa kirjamees ja pastor Johann Heinrich Rosenplänter (1782-1846); kirjamees ja köster Caspar Franz Lorenzsonn (1811-1880); köster Heinrich Gottlieb Lorenzsonn (1803-1847); trükkal ja kirjastaja Friedrich Wilhelm Bonn (1812-1881); linnapead Oskar Alexander Brackmann (1841-1927) ja Jaan Leesment (1870-1941)

  3. Review of: "Hydrologic Change Module (HCM)for PALCO lands dated 12 August 1999, posted at “" (United States)

    Jack Lewis; Robert R. Ziemer


    In general, it appears to be a well-considered and reasonable approach to estimating changes in peak storm runoff from forest harvesting. Our comments that follow are not comprehensive, but focus primarily on Sections 3.0 and 4.4, which are largely based on research at Caspar Creek that Bob Ziemer and Jack Lewis have authored.

  4. Effect of logging on subsurface pipeflow and erosion: coastal northern California, USA (United States)

    R. R. Ziemer


    Abstract - Three zero-order swales, each with a contributing drainage area of about 1 ha, were instrumented to measure pipeflows within the Caspar Creek Experimental Watershed in northwestern California, USA. After two winters of data collection, the second-growth forest on two of the swales was clearcut logged. The third swale remained as an uncut control. After...

  5. Effects of steelhead density on growth of Coho salmon in a small coastal California stream (United States)

    Bret C. Harvey; Rodney J. Nakamoto


    Abstract - Weight change in age-0 coho salmon, Oncorhynchus kisutch at about natural density was negatively related to the density of juvenile steelhead (anadromous rainbow trout O. mykiss) in a 6-week experiment conducted in July-August 1993 in the north and south forks of Caspar Creek, California. The experiment used 12 enclosed stream sections, each containing a...

  6. Habitat-dependent interactions between two size-classes of juvenile steelhead in a small stream (United States)

    Bret C. Harvey; Rodney J. Nakamoto


    Abstract - The presence of small steelhead (Oncorhynchus mykiss; averaging 55 mm fork length) influenced the growth of larger juvenile steelhead (90 mm fork length) during a 6-week experiment conducted in North Fork Caspar Creek, California, in summer 1994. In fenced replicate deep stream sections in this small stream, growth of the larger steelhead was greater in...

  7. NATO Independent Cost Estimating and the Role of Life Cycle Cost Analysis in Managing the Defence Enterprise (Estimation independante des couts de l’OTAN et role de l’analyse des couts globaux de possesssion au sen de l’OTAN) (United States)


    Tortuga LSD 46 LSD 6 1990 United States Rushmore LSD 47 LSD 7 1991 United States Ashland LSD 48 LSD 8 1992 United States Harpers Ferry LSD 49 LSD 1...LM5 LM6 LM7 LM8 LM9 Svalbard Carlskrona Thomaston Plymouth Rock Lyme Bay Anchorage Whidbey Island Raleigh Tortuga Protecteur Atle Largs Bay Fort...8217 Comstock Tortuga Rushmore Ashland ’Harpers Ferry’ ’Carter Hall’ ’Oak Hill’ ’Pearl Harbour’ Siroco Albion Bulwark ’Largs Bay’ ’Lyme Bay’ ’Mounts Bay

  8. "A Myth Becomes Reality": Kaspar Hauser as Messianic Wild Child

    Directory of Open Access Journals (Sweden)

    Ulrich Struve


    Full Text Available The topos of the "Wild Child" occupies an important place in the mythic and literary imagination of the West. The European climax of a long line of wild children, Kaspar Hauser was a nineteenth-century German foundling whose fate has inspired a host of novels, dramas, novellas, poems, songs, and movies, even an opera and a ballet. It has been treated by Paul Verlaine, R. M. Rilke, and Klaus Mann, by the Dada poet Hans Arp, by the dramatist Peter Handke, and by the filmmaker Werner Herzog. This article offers a brief historical sketch of Hauser's life before discussing a key aspect of the literary Kaspar Hauser reception: the motif of the foundling as a latter-day messiah. By examining a set of twentieth-century texts that develop this motif in an exemplary manner—Jakob Wassermann's novel Caspar Hauser or The Inertia of the Heart , Georg Trakl's Kaspar Hauser Song , the anthroposophist Kaspar Hauser poems by Emma Krell-Werth, and David Constantine's Caspar Hauser: A Poem in Nine Cantos —we can gain insight into our century's desire for redemption and its ethical ramifications.

  9. Caspar Wessel (1745-1818). Surveyor and Mathematician

    DEFF Research Database (Denmark)

    Branner, Bodil; Johansen, Nils Voje


    as 1787. In 1797 his mathematical paper "On the Analytical Representation of Direction. An Attempt Applied Chiefly to Solving Plane and Spherical Polygons" (in Danish) was accepted for publication in the Collected Papers of the Academy. The articleis today recognised as the first to contain...

  10. From Albion's shore: Lord Byron' poetry in Slovene translations until 1945

    Directory of Open Access Journals (Sweden)

    Igor Maver


    Full Text Available The publication in 1830 of the early poems of the doyen of Slovene poetry - Dr France Prešeren  in Kranjska čbelica (The Carniola Bee - marks the beginning of Slovene Romanticism, which ends in 1848, -with the last of his poems published in the fifth volume of the same literary magazine. The period from 1830 to the »revolutionary« year of 1848 is thus committed to Romanticism as the leading movement of Slovene literature, artfully embodied in Prešeren's fine lyrical poetry that aimed at and considerably contributed to national unification and identification, as well as in the Europe-oriented literary criticism of Matija čop.  Comparing the trends of the English and Slovene Romantic Revival, we can readily establish that the emergence of Romantic tenets expressed in poetry was somewhat late on Slovene ground. In England, of course, the crucial years are1789, when Lyrical Ballads were published by Wordsworth and Coleridge, and the year 1832, which marks the death of Sir Walter Scott.


    Directory of Open Access Journals (Sweden)

    Ana Paula de Toledo Soares


    Full Text Available This paper aims to elaborate a reflection that follows the displacement of the human view of nature, in the 19th century to the 20th century. Our focus of observation is Gerd Bornheim’s reflections, as well as Deleuze and Schelling’s texts. We selected as object of analysis one Caspar David Friedrich’s screen and Walt Whitman and Alberto Caeiro’s poems, to elaborate the questions.


    Directory of Open Access Journals (Sweden)

    Eugenia V. Ivanova


    Full Text Available The article examines the development of the genre of biography and life writing that influenced Russian biographical tradition. This tradition stems from Plutarch’s Comparative Biographies that influenced English life writing represented by such names as James Boswell, Lytton Strachey, and others. Philosophical premises of the English biography genre are to be found in the treatise Heroes, HeroWorship, and The Heroic in History (1841 by Thomas Carlyle. French tradition represented by Gaston Tissandier’s book Science Martyrs pursued the opposite aim: to honor ordinary scientists and inventors, responsible for the technical advance of the modern civilization. Wilhelm Dilthey and Georg Simmel practiced a different approach to life writing in that they conceived biography as the history of the person’s spiritual development. This conception had direct influence on the theorists of biography genre in Russia, G. O. Vinokur, and A. G. Gabrichevsky.

  13. The sandfly Lutzomyia longipalpis LL5 embryonic cell line has active Toll and Imd pathways and shows immune responses to bacteria, yeast and Leishmania. (United States)

    Tinoco-Nunes, Bruno; Telleria, Erich Loza; da Silva-Neves, Monique; Marques, Christiane; Azevedo-Brito, Daisy Aline; Pitaluga, André Nóbrega; Traub-Csekö, Yara Maria


    Lutzomyia longipalpis is the main vector of visceral leishmaniasis in Latin America. Sandfly immune responses are poorly understood. In previous work we showed that these vector insects respond to bacterial infections by modulating a defensin gene expression and activate the Imd pathway in response to Leishmania infection. Aspects of innate immune pathways in insects (including mosquito vectors of human diseases) have been revealed by studying insect cell lines, and we have previously demonstrated antiviral responses in the L. longipalpis embryonic cell line LL5. The expression patterns of antimicrobial peptides (AMPs) and transcription factors were evaluated after silencing the repressors of the Toll pathway (cactus) and Imd pathway (caspar). AMPs and transcription factor expression patterns were also evaluated after challenge with heat-killed bacteria, heat-killed yeast, or live Leishmania. These studies showed that LL5 cells have active Toll and Imd pathways, since they displayed an increased expression of AMP genes following silencing of the repressors cactus and caspar, respectively. These pathways were also activated by challenges with bacteria, yeast and Leishmania infantum chagasi. We demonstrated that L. longipalpis LL5 embryonic cells respond to immune stimuli and are therefore a good model to study the immunological pathways of this important vector of leishmaniasis.

  14. Combination of the auxins NAA, IBA, and IAA with GA3 improves the commercial seed-tuber production of potato (Solanum tuberosum L.) under in vitro conditions. (United States)

    Kumlay, Ahmet Metin


    The study compared the effects of 1.0 × MS medium containing various concentrations of α-naphthaleneacetic acid (NAA), indole-3-acetic acid (IAA), and indole-3-butyric acid (IBA), alone or in combination with gibberellic acid (GA3) in micropropagation of three potato (Solanum tuberosum L.) cultivars Pasinler, Granola, and Caspar using binodal stem cuttings. The results testified improved regeneration on 1.0 × MS medium containing variants of NAA, IAA, and IBA plus GA3 on all cultivars. The minimum days to shoot induction on three cultivars ranged 4.25-5 d on 1.0 × MS medium containing 0.25 mg L(-1) GA3 + 1 mg L(-1) NAA. The longest shoots (11.8 cm), maximum number of nodes (13.50), and maximum number of leaves (11.00) were recorded on cv. Caspar on 1.0 × MS medium containing 1 mg L(-1) NAA + 0.25 mg L(-1) GA3. The minimum time to root induction (12.25 d) was noted on cv. Pasinler on the same medium. All of the regenerated shoots could be easily rooted. The results showed that the combined effect of various concentrations of NAA, IAA, and IBA plus GA3 was more pronounced compared to the auxins used alone. The results of this research are of significant importance for potato breeders.

  15. New Insights into Viral Architecture via Affine Extended Symmetry Groups

    Directory of Open Access Journals (Sweden)

    T. Keef


    Full Text Available Since the seminal work of Caspar and Klug on the structure of the protein containers that encapsulate and hence protect the viral genome, it has been recognized that icosahedral symmetry is crucial for the structural organization of viruses. In particular, icosahedral symmetry has been invoked in order to predict the surface structures of viral capsids in terms of tessellations or tilings that schematically encode the locations of the protein subunits in the capsids. Whilst this approach is capable of predicting the relative locations of the proteins in the capsids, a prediction on the relative sizes of different virus particles in a family cannot be made. Moreover, information on the full 3D structure of viral particles, including the tertiary structures of the capsid proteins and the organization of the viral genome within the capsid are inaccessible with their approach. We develop here a mathematical framework based on affine extensions of the icosahedral group that allows us to address these issues. In particular, we show that the relative radii of viruses in the family of Polyomaviridae and the material boundaries in simple RNA viruses can be determined with our approach. The results complement Caspar and Klug's theory of quasi-equivalence and provide details on virus structure that have not been accessible with previous methods, implying that icosahedral symmetry is more important for virus architecture than previously appreciated.

  16. BMC Ecology image competition 2014: the winning images. (United States)

    Harold, Simon; Henderson, Caspar; Baguette, Michel; Bonsall, Michael B; Hughes, David; Settele, Josef


    BMC Ecology showcases the winning entries from its second Ecology Image Competition. More than 300 individual images were submitted from an international array of research scientists, depicting life on every continent on earth. The journal's Editorial Board and guest judge Caspar Henderson outline why their winning selections demonstrated high levels of technical skill and aesthetic sense in depicting the science of ecology, and we also highlight a small selection of highly commended images that we simply couldn't let you miss out on.

  17. ‘Hail, reverend Structure!’ Questioning Patriarchal Parenthood in the Aquatic Imagery of Grottoes in Court Masques

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    Caterina Guardini


    Full Text Available Jonson’s Neptune’s Triumph for the Return of Albion (1624, Daniel’s Tethy’s Festival (1610, and Jonson’s Love’s Triumph through Callipolis (1631 explore the representation of royal private and political patriarchy within the Stuart courts of James I and Charles I. By questioning the representation of gender and parenthood, this paper aims at conjecturing the conflictual variety of audience-responses to the aquatic imagery of Mannerist garden grottoes at work in these shows in order to investigate whether the motherly agency of Queen Anna is really erased by James I’s imagery of aquatic patriarchy or if it survives in Charles’s mnemonic reception during his later performances on the masquing stage.

  18. Experiencias en el desarrollo de una aplicación robótica con control de fuerza para taladrado de huesos


    J.C. Fraile; J. Pérez-Turiel; J.L. González-Sánchez; J. López-Cruzado; J.L. Rodríguez


    Resumen: En los sistemas de cirugía ortopédica asistida por ordenador (CAOS), el taladrado del hueso en la reparación de fracturas de huesos largos (para estabilizarlos con placas, clavos o tornillos) es una tarea compleja que el cirujano debe realizar con gran precisión, evitando el calentamiento excesivo del tejido óseo. En la cirugía asistida por robots, se han utilizado principalmente robots industriales (Robodoc, Caspar, Crigos) adaptados a ambientes quirúrgicos para ayudar al cirujano e...

  19. BMC Ecology image competition 2014: the winning images (United States)


    BMC Ecology showcases the winning entries from its second Ecology Image Competition. More than 300 individual images were submitted from an international array of research scientists, depicting life on every continent on earth. The journal’s Editorial Board and guest judge Caspar Henderson outline why their winning selections demonstrated high levels of technical skill and aesthetic sense in depicting the science of ecology, and we also highlight a small selection of highly commended images that we simply couldn’t let you miss out on. PMID:25178017

  20. Das Eismeer – Caspar David Friedrich and the North

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    Nina Hinrichs


    1840 created the work of art Das Eismeer in the years 1823/24. Besides his painting Mönch am Meer it is his most radical painting. It depicts a dramatic and grim subject: A shipwreck in the Arctic Sea. According to different cultural, historical and social contexts there have been many different interpretations of his painting since it was produced.

  1. Combination of the Auxins NAA, IBA, and IAA with GA3 Improves the Commercial Seed-Tuber Production of Potato (Solanum tuberosum L.) under In Vitro Conditions (United States)

    Kumlay, Ahmet Metin


    The study compared the effects of 1.0 × MS medium containing various concentrations of α-naphthaleneacetic acid (NAA), indole-3-acetic acid (IAA), and indole-3-butyric acid (IBA), alone or in combination with gibberellic acid (GA3) in micropropagation of three potato (Solanum tuberosum L.) cultivars Pasinler, Granola, and Caspar using binodal stem cuttings. The results testified improved regeneration on 1.0 × MS medium containing variants of NAA, IAA, and IBA plus GA3 on all cultivars. The minimum days to shoot induction on three cultivars ranged 4.25–5 d on 1.0 × MS medium containing 0.25 mg L−1  GA3 + 1 mg L−1 NAA. The longest shoots (11.8 cm), maximum number of nodes (13.50), and maximum number of leaves (11.00) were recorded on cv. Caspar on 1.0 × MS medium containing 1 mg L−1  NAA + 0.25 mg L−1 GA3. The minimum time to root induction (12.25 d) was noted on cv. Pasinler on the same medium. All of the regenerated shoots could be easily rooted. The results showed that the combined effect of various concentrations of NAA, IAA, and IBA plus GA3 was more pronounced compared to the auxins used alone. The results of this research are of significant importance for potato breeders. PMID:25028654

  2. Glarus - Blanchiment


    Fluck , Pierre


    Cette usine se trouve dans la vallée du Strengenbach, à l'écart de la ville (23 établissements au cours des XVIIIème et XIXème siècles). On pratiquait autour de cet établissement le blanchiment sur prés. A l'origine, elle s'appellait Caspar Vogel. En 1850, elle devint David Pabst. En 1855, un incendie ravagea les bâtiments. Nouvelle construction en 1863, pour devenir en 1864 : Speich, Pabst & Streiff. En 1869, la raison sociale est Streiff & Cie. Aujourd'hui : Bleicherei Streiff AG.

  3. Axes, planes and tubes, or the geometry of embryogenesis. (United States)

    Brauckmann, Sabine


    The paper presents selected figures of chick embryogenesis as depicted in the classic studies of Caspar Friedrich Wolff (1734-1794), Christian Heinrich Pander (1794-1865) and Karl Ernst von Baer (1792-1786). My main objective here is (1) to demonstrate how the imagery of Wolff, Pander and Baer attempted to project an image of a 3-dimensional rotating body into static figures on paper by means of linear contours, and (2) to ponder on the efficacy and pervasiveness of dots, lines and arrows for depicting embryogenesis. Copyright © 2011 Elsevier Ltd. All rights reserved.

  4. Kunst-Gedanken in Tiecks «Franz Sternbalds Wanderungen»

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    Wolfgang Nehring


    Full Text Available Ludwig Tieck is not only the most productive and stimulating power of German Roman­ticism with respect to literature but also, largely unnoticed by his contemporaries and critics, an innovative proponent of a new art. His Sternbald goes way beyond the position of Wackenroder’s Herzensergießungen from which it started. It not only influenced the artwork of the two most important romantic painters, Philipp Otto Runge and Caspar David Fried­rich, but advocates, in a way, twentieth-century ideas of modern painting.


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    Full Text Available RESUMO O objetivo do trabalho foi estimar a soma térmica e o filocrono de quatro cultivares e duas ‘seleções’ de morangueiro para o Planalto Sul- Catarinense. O experimento foi conduzido no Centro de Ciências Agroveterinárias, na Universidade do Estado de Santa Catarina. Foram utilizadas duas seleções de morangueiro em avançada fase de estudos, denominadas ‘SEL1’ e ‘SEL2’, utilizando mudas provenientes de um programa público de melhoramento genético da Itália e quatro cultivares: Camino Real e Camarosa, provenientes do Chile, e San Andreas eAlbion, provenientes da Argentina. O transplante das mudas foi realizado em 26-06-2012. O delineamento experimental utilizado foi o de blocos ao acaso, com três repetições, cada repetição composta de oito plantas, sendo utilizadas as quatro plantas centrais. O filocrono foi determinado a partir do inverso do coeficiente angular da regressão linear entre o número de folhas acumuladas na haste e a soma térmica acumulada após o transplante. Observou-se linearidade entre o desenvolvimento vegetal e a temperatura média do ar nas condições do estudo. Dentre as seleções e cultivares estudadas a ‘San Andreas’ apresenta o ciclo mais precoce, necessitando de menor acúmulo de temperatura (774,70 grausdia, e a cultivar Camarosa, o ciclo mais tardio, com maior acúmulo de soma térmica (1.137,75 graus-dia. A seleção Sel1 apresentou o menor filocrono, 69,96ºC dia1 folha-1, e a cultivar Albion maior valor, 135,61 oC dia1 folha-1. Durante o período estudado, a cultivar San Andreas apresentou maior produção de frutos.

  6. H-2g, a glucose analog of blood group H antigen, mediates monocyte recruitment in vitro and in vivo via IL-8/CXCL8

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    Rabquer BJ


    Full Text Available Bradley J Rabquer,1,2 Yong Hou,1 Jeffrey H Ruth,1 Wei Luo,1 Daniel T Eitzman,1 Alisa E Koch,3,1 Mohammad A Amin11University of Michigan Medical School, Department of Internal Medicine, Ann Arbor, MI, USA; 2Albion College, Biology Department, Albion, MI, USA; 3VA Medical Service, Department of Veterans Affairs, Ann Arbor, MI, USAObjective: Monocyte (MN recruitment is an essential inflammatory component of many autoimmune diseases, including rheumatoid arthritis (RA. In this study we investigated the ability of 2-fucosyllactose (H-2g, a glucose analog of blood group H antigen to induce MN migration in vivo and determined if H-2g-induced interleukin-8 (IL-8/CXCL8 plays a role in MN ingress in RA.Methods: Sponge granuloma and intravital microscopy assays were performed to examine H-2g-induced in vivo MN migration and rolling, respectively. MNs were stimulated with H-2g, and the production of IL-8/CXCL8 was assessed by enzyme-linked immunosorbent assay and quantitative polymerase chain reaction. Lastly, in vitro MN migration assays and an in vivo RA synovial tissue severe combined immunodeficiency mouse model were used to determine the role of IL-8/CXCL8 in H-2g-induced MN migration.Results: In vivo, H-2g induced significantly greater MN migration compared to phosphate buffered saline. Intravital microscopy revealed that H-2g mediates MN migration in vivo by inducing MN rolling. In addition, H-2g induced MN production of IL-8/CXCL8, a process that was dependent on Src kinase. Moreover, we found that H-2g mediated MN migration in vitro, and in vivo migration was inhibited by a neutralizing anti-IL-8/CXCL8 antibody.Conclusion: These findings suggest that H-2g mediates MN recruitment in vitro and in vivo (in part via IL-8/CXCL8.Keywords: inflammation, rheumatoid arthritis, chemokine, migration

  7. Decision management - projects subject to uncertainty

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    A.E. Paterson


    Full Text Available The human mind is normally unable to grasp more than five to nine aspects relating to the same decision circumstances simultaneously. It has been demonstrated that only between four and eight variables significantly affect return on engineering projects (at the 90% level irrespective of scale. The most powerful means of isolating these significant variables is by computer simulation. This is demonstrated through the application of the interactive CASPAR programme to a simulated mining project. The significant variables are separated into controllable, influence able and uncontrollable categories for decision and control purposes since the nature of the speculative risk differs. The managerial treatment of each category is discussed.

  8. [From Vesalius to Descartes: the heart, the life]. (United States)

    Bitbol-Hespériès, Annie


    At the end of 1629, Descartes, settled in the Lower Countries, began studying anatomy and performing dissections in order to write L'Homme (The Treatise on Man). He acknowledged his debt towards "Vezalius and the others". In those years, in Europe, the influence of Vesalius was increasing, as shown by Rembrandt's Anatomy of Dr Tulp and by the Theatrum anatomicum by Caspar Bauhin. Descartes rejected the divisions of the soul, then a common place in medical treatises, and he stated a principle of life defined by the heath in the heart linked to the new demonstration of the circulation of the blood by William Harvey.

  9. Seismic data acquisition at the FACT site for the CASPAR project.

    Energy Technology Data Exchange (ETDEWEB)

    Jones, Kyle R.; Chael, Eric Paul; Hart, Darren M.


    Since May 2010, we have been recording continuous seismic data at Sandia's FACT site. The collected signals provide us with a realistic archive for testing algorithms under development for local monitoring of explosive testing. Numerous small explosive tests are routinely conducted around Kirtland AFB by different organizations. Our goal is to identify effective methods for distinguishing these events from normal daily activity on and near the base, such as vehicles, aircraft, and storms. In this report, we describe the recording system, and present some observations of the varying ambient noise conditions at FACT. We present examples of various common, non-explosive, sources. Next we show signals from several small explosions, and discuss their characteristic features.

  10. Elzevirian Republics, wise merchants, and new perspectives on Spain and Portugal in the seventeenth-century Dutch Republic

    Directory of Open Access Journals (Sweden)

    Sina Rauschenbach


    Full Text Available Between 1625 and 1649, the Leiden publishing house Elzevir issued a series of thirty-five descriptions of all European, a selection of non-European, and three ancient states, that became known as the ‘Elzevirian Republics’. This essay focuses on two of these ‘Republics’, Johannes de Laet’s descriptions of Spain and Portugal. I argue that these books convey an attitude towards geopolitics that is best understood in the light of Caspar Barlaeus’s ideal of the ‘wise merchant’ (mercator sapiens and the historical regent-merchant culture in seventeenth-century Amsterdam. The essay draws on recent scholarship in the history of knowledge, commerce, and the pre-history of objectivity.

  11. A Cross-Cultural Comparison of Three Risk Tolerance Measures: Turkey and the United States Case

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    Jorge Ruiz-Manjivar


    Full Text Available An individual’s attitude toward financial risk tolerance (FRT is an important preference that influences financial decision-making under uncertainty. FRT involves inter-temporal resource allocation. Accurate and reliable measures of FRT are essential for professionals advising consumers as well as researchers who are trying to predict, and understand consumer behavior. This study explores cross-cultural risk tolerance by comparing random samples from Turkey, and the United States. Similar and distinctive attitudes and patterns regarding FRT are identified. Three subjective measures of FRT are employed in this study: Grable and Lytton (1999, Hanna, Gutter and Fan’s (2001 improved version of Barsky, Juster, Kimball and Shapiro (1997, and the Survey of Consumer Finance’s item on risk tolerance. Data was collected via an online survey that used the above-mentioned FRT measures. There were two versions: the original American English version, and a culturally translated Turkish version. To explore the correlation of FRT among measures, we use bivariate analysis by individually employing Pearson Chi-square test of independence, and cross tabulations analysis to each sample. In addition, by pooling both samples, we conduct cumulative logistic regression. We delineate FRT differences and consistencies between countries across subjective financial risk tolerance measures.

  12. 'National Hero and Very Queer Fish': Empire, Sexuality and the British Remembrance of General Gordon, 1918-72. (United States)

    Jones, Max


    This article presents the first detailed study of General Gordon's remembrance in Britain between 1918 and 1972. Previous scholars have exaggerated the impact of Lytton Strachey's Eminent Victorians (1918). Strachey damaged Gordon's reputation, but part one reveals how several commentators forcefully rebutted Eminent Victorians; official commemorations, books, radio plays, and films celebrated Gordon in the 1930s, as empire featured prominently in mass culture. Didactic uses of his example by the state diminished after 1945, but parts 2 and 3 show how writers used Gordon's story to engage with new debates about Britain's role in the world, immigration and sexuality. The article reveals how a fascination with the sexuality of heroes inspired men as diverse as Viscount Robin Maugham and East End gangster Ronnie Kray to identify with Gordon. Maugham's works and the feature film Khartoum (1966) expressed nostalgia for empire during decolonization, but American screenwriter Robert Ardrey also drew on his experiences in the Congo to present a dark vision of African savagery in Khartoum, a vision performed at Pinewood studios by black immigrants from London's slums. The article questions Edward Berenson's emphasis on the 'charismatic aura' of heroes, emphasizing instead the diversity of engagements inspired through different genre.

  13. Aliens and time in the machine age (United States)

    Brake, Mark; Hook, Neil


    The 19th century saw sweeping changes for the development of astrobiology, both in the constituency of empirical science encroaching upon all aspects of life and in the evolution of ideas, with Lyell's Principles of Geology radically raising expectation of the true age of the Earth and the drama of Darwinism questioning biblically literalist accounts of natural history. This paper considers the popular culture spun on the crackling loom of the emergent aspects of astrobiology of the day: Edward Bulwer-Lytton's The Coming Race (1871), which foretold the race of the future, and satirist Samuel Butler's anticipation of machine intelligence, `Darwin Among the Machines', in his Erewhon (1872). Finally, we look at the way Darwin, Huxley and natural selection travelled into space with French astronomer Camille Flammarion's immensely popular Récits de l'infini (Stories of Infinity, 1872), and the social Darwinism of H.G. Wells' The Time Machine (1895) and The War of the Worlds (1898). These works of popular culture presented an effective and inspiring communication of science; their crucial discourse was the reducible gap between the new worlds uncovered by science and exploration and the fantastic strange worlds of the imagination. As such they exemplify a way in which the culture and science of popular astrobiology can be fused.

  14. Effect of hydro-ethanolic extracts of cinnamon (Cinnamomum zeylanicum Blume and common horsetail (Equisetum arvense L. on incidence and severity of Botrytis cinerea on strawberry

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    Pazmiño-Miranda Pilar


    Full Text Available The effect of application of three dosages (5, 10 and 15 mL/L and two frequencies (each 6 and 8 days of ethanoic extracts obtained from cinnamon (Cinnamomum zeylanicum Blume and common horsetail (Equisetum arvense L. on incidence and severity of grey mould (Botrytis cinerea on strawberry crop (Fragaria ananassa cv. Albion was evaluated. Experiment was carried out in a randomized block design with factorial arrangement 2 x 3 x 2 + 1, with three replications. Lower incidence and severity percentage in flower and fruit (10.24 and 24.43%, respectively were observed after application of cinnamon extract at 15 mL/L at 6 days interval. Similarly, lower fruit severity (11.86% was observed with the same treatment. In general, reduction in B. cinerea incidence and severity was lower when common horsetail extract was used, compared to cinnamon extracts. According to our results, using of cinnamon hydro-ethanoic extracts could be considered as sustainable alternative for grey mold management in strawberry crops.


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    Ivna Štolfa


    Full Text Available Proper postharvest storage is an effective way to maintain the quality and nutritional values of fruits. The aim of this study was to determine how environmentally friendly postharvest treatments with salicylic acid solution, colloidal silver solution and ozone, affect the antioxidant activity of strawberry fruits (Fragaria x ananassa Duch. cv. Albion during 7 days of storage at 4°C. The content of ascorbic acid, total phenols and antioxidant activity of strawberry fruits were determined spec-trophotometrically. After 7 days of storage in strawberry fruits treated with all three treatments separately, the contents of ascorbic acid were higher than in the control fruits, supporting the usefulness of these treatments for preserving fruit quality and nutritional value during storage. The treatment with salicylic acid solution showed the most beneficial effect during storage causing a significant increase in the content of ascorbic acid, phenols and antioxidant activity at the end of the storage period.

  16. TbNb6Sn6: the first ternary compound from the rare earth–niobium–tin system

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    Viktor Hlukhyy


    Full Text Available The title compound, terbium hexaniobium hexastannide, TbNb6Sn6, is the first ternary compound from the rare earth–niobium–tin system. It has the HfFe6Ge6 structure type, which can be analysed as an intergrowth of the Zr4Al3 and CaCu5 structures. All the atoms lie on special positions; their coordination geometries and site symmetries are: Tb (dodecahedron 6/mmm; Nb (distorted icosahedron 2mm; Sn (Frank–Caspar polyhedron, CN = 14–15 6mm and overline{6}m2; Sn (distorted icosahedron overline{6}m2. The structure contains a graphite-type Sn network, Kagome nets of Nb atoms, and Tb atoms alternating with Sn2 dumbbells in the channels.

  17. Heavenly Networks. Celestial Maps and Globes in Circulation between Artisans, Mathematicians, and Noblemen in Renaissance Europe. (United States)

    Gessner, Samuel


    The aim of this paper is to examine the iconography on a set of star charts by Albrecht Dürer (1515), and celestial globes by Caspar Vopel (1536) and Christoph Schissler (1575). The iconography on these instruments is conditioned by strong traditions which include not only the imagery on globes and planispheres (star charts), but also ancient literature about the constellations. Where this iconography departs from those traditions, the change had to do with humanism in the sixteenth century. This "humanistic" dimension is interwoven with other concerns that involve both "social" and "technical" motivations. The interplay of these three dimensions illustrates how the iconography on celestial charts and globes expresses some features of the shared knowledge and shared culture between artisans, mathematicians, and nobles in Renaissance Europe.

  18. Johannes Kepler and his contribution to Applied Mathematics (United States)

    Pichler, Franz

    The worldwide renown of Johannes Kepler is based above all on his contribution to astronomy. The 3 Kepler's Laws relating to the planets are well known and will ensure that his name is remembered by future generations. Besides his astronomical work, Kepler also made important contributions in the fields of theology, physics, phylosophy and mathematics. The actual paper discusses the advances by Kepler in the application of mathematics to the solution of "real life problems". The author made a concise account of some of the disciples by Kepler: Klug, Wieleitner, Caspar, Hammer, paying particular attention to works published by Kepler while he was living in Linz (1612-1628). The Kepler's contribution to applied mathematics is an example supremely worthy of emulation, the author concludes.

  19. The Four Lives of a Nuclear Accelerator (United States)

    Wiescher, Michael


    Electrostatic accelerators have emerged as a major tool in research and industry in the second half of the twentieth century. In particular in low energy nuclear physics they have been essential for addressing a number of critical research questions from nuclear structure to nuclear astrophysics. This article describes this development on the example of a single machine which has been used for nearly sixty years at the forefront of scientific research in nuclear physics. The article summarizes the concept of electrostatic accelerators and outlines how this accelerator developed from a bare support function to an independent research tool that has been utilized in different research environments and institutions and now looks forward to a new life as part of the experiment CASPAR at the 4,850" level of the Sanford Underground Research Facility.

  20. Relationship of Psoriatic Arthritis to Other Spondyloarthritides. (United States)

    Olivieri, Ignazio; D'Angelo, Salvatore; Gilio, Michele; Palazzi, Carlo; Lubrano, Ennio; Padula, Angela


    In the early 1970s, Moll and co-workers formulated the unified concept of spondyloarthritides, a group of conditions sharing similar clinical features. Subsequently, criteria for their classification have been proposed by Amor and coworkers, the European Spondylarthropathy Study Group, and the Assessment in SpondyloArthritis international Society. Opinion, however, is divided between those who believe that the different entities of the complex represent the variable expression of the same disease ("lumpers") and those who think that these should be considered separately but under the same umbrella ("splitters"). Several sets of criteria have been proposed for psoriatic arthritis (PsA), the most recent being the ClASsification for Psoriatic Arthritis (CASPAR) criteria. According to some authors, there are persuasive arguments to support the view of PsA as a distinct entity.

  1. [Carl Gustav Carus, the first director of the newly established maternity institute of the Dresden Royal Surgical-Medical Academy 1814-1827]. (United States)

    Sarembe, B


    Carl Gustav Carus was born in 1789 in Leipzig. He studied at the University of Leipzig. His specialization in Gynecology and Obstetrics took place at the Triersches Maternity Hospital. In 1814 he was named Professor for Obstetrics in Dresden at the Royal-Surgical-Medical-Academy. He was the head of the Maternity Hospital till 1827. Under his direction many midwives, students and physicians were educated. He published numerous articles and books on medical and philosophical-psychological topics. He was a talented artist of the Romantic especially in painting landscapes. He was a friend of Caspar David Friedrich and Johann Wolfgang von Goethe. After 1827 he was the physician in ordinary to 3 saxonian kings. He died in 1869. The Medical Academy in Dresden bears his name "Carl Gustav Carus" since its foundation.

  2. Anatomy and Histology of Rodent and Human Major Salivary Glands (United States)

    Amano, Osamu; Mizobe, Kenichi; Bando, Yasuhiko; Sakiyama, Koji


    Major salivary glands of both humans and rodents consist of three pairs of macroscopic glands: parotid, submandibular, and sublingual. These glands secrete serous, mucous or mixed saliva via the proper main excretory ducts connecting the glandular bodies with the oral cavity. A series of discoveries about the salivary ducts in the 17th century by Niels Stensen (1638–1686), Thomas Wharton (1614–1673), and Caspar Bartholin (1655–1738) established the concept of exocrine secretion as well as salivary glands. Recent investigations have revealed the endocrine functions of parotin and a variety of cell growth factors produced by salivary glands. The present review aims to describe macroscopic findings on the major salivary glands of rodents and the microscopic differences between those of humans and rodents, which review should be of interest to those researchers studying salivary glands. PMID:23209333

  3. Anatomy and histology of rodent and human major salivary glands: -overview of the Japan salivary gland society-sponsored workshop-. (United States)

    Amano, Osamu; Mizobe, Kenichi; Bando, Yasuhiko; Sakiyama, Koji


    MAJOR SALIVARY GLANDS OF BOTH HUMANS AND RODENTS CONSIST OF THREE PAIRS OF MACROSCOPIC GLANDS: parotid, submandibular, and sublingual. These glands secrete serous, mucous or mixed saliva via the proper main excretory ducts connecting the glandular bodies with the oral cavity. A series of discoveries about the salivary ducts in the 17th century by Niels Stensen (1638-1686), Thomas Wharton (1614-1673), and Caspar Bartholin (1655-1738) established the concept of exocrine secretion as well as salivary glands. Recent investigations have revealed the endocrine functions of parotin and a variety of cell growth factors produced by salivary glands.The present review aims to describe macroscopic findings on the major salivary glands of rodents and the microscopic differences between those of humans and rodents, which review should be of interest to those researchers studying salivary glands.

  4. Gloriana de Britten et le rêve de l’opéra anglais Britten’s Gloriana and the dream of english opera

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    Gilles Couderc


    Full Text Available The composition of Benjamin Britten’s sixth opera, Gloriana, originates from a conversation about emblematic national operas, the lack thereof in the British repertory and the need for Britten to compose such an opera to coincide with the Coronation of the young Queen Elizabeth II in 1953. Britten’s insistence on composing such an opera based on the tragic love story between the first Queen Elizabeth and Essex, depicted in Lytton Strachey’s dramatic biography, raises several questions. Why should Britten, the controversial composer of several controversial works, curry royal patronage? Why should he insist on composing for an event of such national significance? Why should Britten ride the hobby horse of a national opera and share the obsession of a national opera common to German composers of the Romantic generation? Gloriana turns out to be one of the elements that point to modernist and cosmopolitan Britten’s great sense of a national identity as a composer and his claim to work within a distinctly English tradition. The Coronation opera is also one of many endeavours in Britten’s production to resuscitate English Opera, his life-long ambition. With Gloriana, Britten once more leads the fight to eradicate English people’s prejudices against musicians in general and their own composers in particular and to give the lie to the dictum that Britain is the country that has no music.

  5. Exhibiting the past: Caspar Reuvens and the museums of antiquities in Europe, 1800-1840

    NARCIS (Netherlands)

    Hoijtink, M.


    In the first decades of the 19th century the exhibition of antiquity in museums reflected a universal history of civilization, in which the idea of cross-cultural influences dominated. Hindu-buddhist civilization of 13th century Java was easily connected to that of classical Greece, and Indian

  6. [Dislocated fracture of the lesser trochanter with malrotation of the stem after robot assisted implantation of a cementless hip prosthesis: a casuistic report]. (United States)

    Prymka, M; Hassenpflug, J


    This paper presents the case of a 63 year old female with a severe coxarthrosis. She got a robot assited implantation of a cementless hip prosthesis (Osteolock, Stryker-Howmedica, Mühlheim). As operation robot the CASPAR-System (Orto-Maquet, Rastatt) was used. Initially, the clinical progress of the patient was fine. She was nearly painfree within 14 days and showed an acceptable range of motion in the operated joint (flexion/ extension 90 degrees /05 degrees /00 degrees ). She was mobilized with crutches and 15 kg weight bearing at the operated leg. 3 weeks postoperative the patient complaint about increasing pain without trauma or intensification of the weight bearing. X-rays showed not only a dislocated fracture of the lesser trochanter, but also a sinking combined with a malrotation of the stem. A revision operation was necessary,where we implanted a cemented stem. Now clinical progress was completely satisfying.

  7. On the heritability of psoriatic arthritis. Disease concordance among monozygotic and dizygotic twins

    DEFF Research Database (Denmark)

    Pedersen, Ole Birger; Svendsen, Anders Jørgen; Ejstrup, Leif


    OBJECTIVE: In a nationwide unselected twin population to estimate the relative importance of genetic and environmental effectors in the etiopathogenesis of psoriatic arthritis (PsA). METHODS: The study comprised three Danish nationwide twin cohorts. In 1994 and 2002 a total of 37,388 and 46......,418 Danish twin individuals respectively were asked by questionnaire if they had PsA. Twins reporting PsA were invited to participate in a clinical examination. Patients were classified according to the Moll and Wright (M&W) and the CASPAR criteria. Heritability was estimated by probandwise concordance rates...... and variance component analysis. RESULTS: 228 twin individuals reported PsA. Following diagnostic validation in 184 (81%), 50 probands were diagnosed with PsA according to the M&W criteria. Five of their co-twins were either dead, had emigrated, or did not participate in the twin study and nine did not respond...

  8. Trial Characteristics as Contextual Factors when Evaluating Targeted Therapies in Patients with Psoriatic Disease

    DEFF Research Database (Denmark)

    Ballegaard, Christine; Jørgensen, Tanja S; Skougaard, Marie


    (PsA) and psoriasis (8 biologics and apremilast). The effect of targeted therapies was analyzed in the two psoriatic conditions combined by using drug retention as common outcome, and separately by using ACR20 for PsA and PASI75 for psoriasis. We explored potential effect modification of trial...... characteristics in stratified and meta-regression analyses. Odds ratios (OR) were calculated and compared among the trial eligibility criteria via the Ratio of Odds Ratios (ROR). RESULTS: Forty-eight PsA and psoriasis trials (51 comparisons, 17,737 patients) were eligible. Overall retention was OR 2.16 (1.70 to 2.......75) with higher odds for PsA trials compared with psoriasis trials (ROR = 2.55 [1.64 to 3.97]). The eligibility criteria "targeted therapy history", "minimum required disease duration", "required negative rheumatoid factor", and "required CASPAR criteria" were of importance for achieving ACR20 in PsA...

  9. First report of a complete genome sequence for a begomovirus infecting Jatropha gossypifolia in the Americas. (United States)

    Simmonds-Gordon, R N; Collins-Fairclough, A M; Stewart, C S; Roye, M E


    Jatropha gossypifolia is a weed that is commonly found with yellow mosaic symptoms growing along the roadside and in close proximity to cultivated crops in many farming communities in Jamaica. For the first time, the complete genome sequence of a new begomovirus, designated jatropha mosaic virus-[Jamaica:Spanish Town:2004] (JMV-[JM:ST:04]), was determined from field-infected J. gossypifolia in the western hemisphere. DNA-A nucleotide sequence comparisons showed closest identity (84 %) to two tobacco-infecting viruses from Cuba, tobacco mottle leaf curl virus-[Cuba:Sancti Spiritus:03] (TbMoLCV-[CU:SS:03]) and tobacco leaf curl Cuba virus-[Cuba:Taguasco:2005] (TbLCuCUV-[CU:Tag:05]), and two weed-infecting viruses from Cuba and Jamaica, Rhynchosia rugose golden mosaic virus-[Cuba:Camaguey:171:2009] (RhRGMV- [CU:Cam:171:09]) and Wissadula golden mosaic St. Thomas virus-[Jamaica:Albion:2005] (WGMSTV-[JM:Alb:05]). Phylogenetic analysis revealed that JMV-[JM:ST:04] is most closely related to tobacco and tomato viruses from Cuba and WGMSTV-[JM:Alb:05], a common malvaceous-weed-infecting virus from eastern Jamaica, and that it is distinct from begomoviruses infecting Jatropha species in India and Nigeria.

  10. The Social Theories of the press: journalism and society

    Directory of Open Access Journals (Sweden)

    Beatriz Marocco


    Full Text Available For a short period of time, between the end of the 19th century and the middle of the 20th, newspapers and journalists were under the spotlight as never before. However, the comprehensive reviews of the theories of the press do not acknowledge the thought of this period and its development into “the social theories of the press” (H. Hardt, 1979. This article is positioned in this gap of press studies, and it uses as a starting point the foucaultian description of the diff erent thresholds that establish the levels of discourse elaboration (Foucault, 1995. It aims at exploring the theoretical production that approximates German and American scholars such as Albert Schäffle (1831-1903; Karl Knies (1821-1898; Karl Bücher (1847-1930; Ferdinand Tönnies (1835-1936; Albion Small (1854-1926; Edward Ross (1856-1951; Max Weber (1864-1920; Robert Park (1864-1944 and Walter Lippmann (1889-1974, rescuing this production from the pre-history of the press to materialize evidence that this production coincides, in its external origin, with the modern newspaper practices, although there seemed to be no dependence between them at the time.

  11. The Social Theories of the press: journalism and society

    Directory of Open Access Journals (Sweden)

    Beatriz Marocco


    Full Text Available For a short period of time, between the end of the 19th century and the middle of the 20th, newspapers and journalists were under the spotlight as never before. However, the comprehensive reviews of the theories of the press do not acknowledge the thought of this period and its development into “the social theories of the press” (H. Hardt, 1979. This article is positioned in this gap of press studies, and it uses as a starting point the foucaultian description of the diff erent thresholds that establish the levels of discourse elaboration (Foucault, 1995. It aims at exploring the theoretical production that approximates German and American scholars such as Albert Schäffle (1831-1903; Karl Knies (1821-1898; Karl Bücher (1847-1930; Ferdinand Tönnies (1835-1936; Albion Small (1854-1926; Edward Ross (1856-1951; Max Weber (1864-1920; Robert Park (1864-1944 and Walter Lippmann (1889-1974, rescuing this production from the pre-history of the press to materialize evidence that this production coincides, in its external origin, with the modern newspaper practices, although there seemed to be no dependence between them at the time.

  12. Environmental law. 2. rev. and enl. ed.; Umweltrecht

    Energy Technology Data Exchange (ETDEWEB)

    Koch, H.J. (ed.) [Hamburg Univ. (Germany). Forschungsstelle Umweltrecht


    The text book under consideration already is addressed to lawyers and students of jurisprudence. It enables an introduction into the general environmental law and consists of sixteen autonomous chapters: (a) International law in the field of ecology (Matthias Buck, Roda Verheyen); (b) European and national environmental constitutional law (Johannes Caspar); (c) General environmental administrative law (Ulrich Ramsauer); (d) Pollution abatement law (Hans-Joachim Koch); (e) Water protection law (Silke Laskowski, Cornelia Ziehm); (f) Recycling economy law and waste management law (Martin Dieckmann, Moritz Reese); (g) Nature conservation law (Christian Maass, Peter Schuette); (h) Soil conservation law and contaminated sites law (Nikolaus Herrmann); (i) Energy legal regulations as an instrument of environmental protection (Wolfgang Ewer); (j) Atomic energy law (Klaus Jankowski); (k) Genetic engineering law (Ursula Prall); (l) Law of hazardous materials (Eckhard Pache); (m) Environmental law in planning law (Nikolaus Hermann); (n) Environment and traffic (Philipp Hermann, Ekkehard Hofmann); (o) Agriculture and ecology (Ulf-Henning Moeker); (p) Liberal trade and environmental protection (Matthias Buck).

  13. [Phenomenological anthropological social psychiatry--paving the way for a theoretical reanimation]. (United States)

    Thoma, Samuel


    This article tries to link the present lack of theoretical discussion within German Social Psychiatry with a loss of phenomenological and anthropological thought. The so-called Phenomenological Psychiatry used to play a very important role in German psychiatry during the 50 ies until the 70 ies and had strong influences on the first reformers of German psychiatry, such as Walter Ritter von Baeyer, Heinz Häfner, Caspar Kulenkampff, Karl Peter Kisker and Erich Wulff. Their reforms were not only founded by a social criticism put forth by theories such as marxism (Basaglia, Wulff) or structuralism (Foucault) but also by a concrete notion of what it is like to suffer from mental illness and what kind of needs are linked to such suffering. This very notion was given by the phenomenological approach. Finally the article tries to give reasons for today's reciprocal loss of connection of the phenomenological and the socio-psychiatric school. © Georg Thieme Verlag KG Stuttgart · New York.

  14. Laboratory Astrophysics Prize: Laboratory Astrophysics with Nuclei (United States)

    Wiescher, Michael


    Nuclear astrophysics is concerned with nuclear reaction and decay processes from the Big Bang to the present star generation controlling the chemical evolution of our universe. Such nuclear reactions maintain stellar life, determine stellar evolution, and finally drive stellar explosion in the circle of stellar life. Laboratory nuclear astrophysics seeks to simulate and understand the underlying processes using a broad portfolio of nuclear instrumentation, from reactor to accelerator from stable to radioactive beams to map the broad spectrum of nucleosynthesis processes. This talk focuses on only two aspects of the broad field, the need of deep underground accelerator facilities in cosmic ray free environments in order to understand the nucleosynthesis in stars, and the need for high intensity radioactive beam facilities to recreate the conditions found in stellar explosions. Both concepts represent the two main frontiers of the field, which are being pursued in the US with the CASPAR accelerator at the Sanford Underground Research Facility in South Dakota and the FRIB facility at Michigan State University.

  15. Epigenesis in Kant: Recent reconsiderations. (United States)

    Zammito, John H


    Epigenesis has become a far more exciting issue in Kant studies recently, especially with the publication of Jennifer Mensch's Kant' Organicism. In my commentary, I propose to clarify my own position on epigenesis relative to that of Mensch and others by once again considering the discourse of epigenesis in the wider eighteenth century. Historically, I maintain that Kant was never fully an epigenesist because he feared its materialist implications. This makes it highly unlikely that he drew heavily, as other interpreters like Dupont and Huneman have suggested, on Caspar Friedrich Wolff for his ultimate theory of "generic preformation." In order to situate more precisely what Kant made of epigenesis, I distinguish his metaphysical use, as elaborated by Mensch, from his view of it as a theory for life science. In that light, I raise questions about the scope and authority of philosophy vis a vis natural science. Copyright © 2016 Elsevier Ltd. All rights reserved.

  16. Annual Report to the Congress, Fiscal Year 1988, Caspar W. Weinberger, Secretary of Defense. Executive Summary. (United States)


    these threats are not merely isolated occurrences. Terrorism is increasingly transnacional and state-supported. Drug trafficking is increasingly...deter- rence and defense through their presence abroad and by our capability to deploy them from the continental United States (CONUS) to crisis areas

  17. Tratamento cirúrgico das lesões traumáticas do segmento médio-inferior da coluna cervical

    Directory of Open Access Journals (Sweden)



    Full Text Available O nível C2 é o mais frequente em lesões traumáticas da coluna cervical, sendo seguido por C5 e C6. Elas ocorrem, mais habitualmente, na terceira década de vida, com incidência decrescente na idade avançada. Como parte destas lesões está localizada nos elementos da coluna anterior, segundo a conceituação de Denis e, levado-se em consideração os estudos biomecânicos do segmento médio--inferior da coluna cervical, bem como os mecanismos que causam estas lesões, elaboramos este estudo, com o intuito de apresentar as técnicas de fusão cervical anterior, com enxerto ósseo e placas de Caspar, Morscher (CSLP e ORION(TM. Mostramos e discutimos as vantagens e desvantagens de cada tipo de fixação anterior, com base nos dados de literatura, evidenciando a melhoria no material de implante e das técnicas de fixação.

  18. Toxicological studies on the insecticides azinphosmethyl ( guthion ) and carbaryl in albion rats with special reference to the metabolism of 14 c- naphthyl

    International Nuclear Information System (INIS)

    Wafa, D.M.


    1-pesticides are among the group of foreign chemicals now polluting the environment, but also are essential to man's well being as they provide both protection of food crops from pests and humans from insect-borne disease. 2- in the present investigation, toxicological studies on the two insecticides: azinphosmethyl (organophosphorus) and carbaryl (carbamate) have been made. the comparative effects of the insecticides on acetylcholinesterase activity in brain, erthrocytes and plasma have been studied for different periods in albino rats. 3- there is considerable information available concerning the metabolism of azinphosmethyl (guthion), yet some aspects of carbaryl metabolism need further verifications. For this reason, the metabolism of labeled 14 c-naphthyl carbaryl has been studied in vivo in the present investigation to add further knowledge on the metabolism of carbaryl, and to find out possible relationship that may exist between carbaryl toxicity and its metabolism

  19. Ouida: the Fascination of Moral Laxity Ouida : fascination pour un relâchement de la morale

    Directory of Open Access Journals (Sweden)

    Franco Marucci


    Full Text Available Ouida (pseudonyme de Marie Louise de la Ramée, 1839-1908 quitta Bury St. Edmunds pour Londres en 1857, où l’influence de William Ainsworth, alors rédacteur en chef de Bentley’s Miscellany, lui valut une réputation de romancière. Installée à Florence dès les années 1870, elle y composa d’excellents romans, trépidants et romantiques, sur la haute société, essentiellement à la demande de l’éditeur allemand Tauchnitz, et brossa, dans d’autres, des portraits attendris de la vie paysanne de la Toscane et de la Maremme. Elle finit sa vie dans la pauvreté et mourut à Viareggio. Prolifique et multiforme, son œuvre comprend poésies, pièces de théâtre, livres pour enfants et récits de voyages, ainsi que des essais sur l’esthétique, la politique et la sociologie. Quoiqu’admirée de son vivant par Edward Bulwer Lytton et John Ruskin, sa réputation reste celle d’un écrivain mineur. Profitant du centenaire de sa mort, cet article se propose de redonner à Ouida sa juste place dans la littérature. Il y est question de son thème de prédilection – une fascination ambiguë pour la haute société aux mœurs relâchées, telle qu’on le retrouve dans les romans dits de sa « période majeure », Under Two Flags, Moths, Puck – et, de manière plus fouillée, dans Bertie Cecil, personnage hanté par une étrange et mystérieuse apathie, un fatalisme et une volonté d’anéantissement identitaire.

  20. Barbarian medicine in feudal Japan. (United States)

    Fodstad, Harald; Hariz, Marwan I; Hirabayashi, Hidehiro; Ohye, Chihiro


    THE FIRST EUROPEANS to discover Japan were Portuguese traders who arrived in 1542. Fifteen years later, the Portuguese Jesuit priest and surgeon Luis De Almeida (1525-1583) founded the first Western hospital in Japan, for the care of lepers, syphilitics, and orphans. Because the hospital had a negative influence on the spread of Christianity, the Jesuits closed it in 1586. During the Tokugawa Shogunate (1600-1868), when Japan was secluded from the rest of the world, the only foreign physicians allowed to enter Japan were those employed by the Dutch factory at Dejima in Nagasaki. Only four of those physicians left behind seeds for the foundation of Western medicine in Japan, namely Caspar Schambergen, who founded a Japanese school of surgery in 1650; Engelbert Kämpfer, who visited Japan in 1691 to 1692; Carl Peter Thunberg, who botanically explored Japan in 1775 to 1776; and Philipp Franz Balthasar von Siebold, who practiced medicine in Nagasaki in 1823 to 1829 and 1859 to 1861. On the whole, Western medicine and surgery never established a real foothold in Japan until the fall of the shogunate and the restoration of the emperor in 1868.

  1. Review: Disabled Addicted Women

    Directory of Open Access Journals (Sweden)

    Farideh Hemmati


    Full Text Available Women have suffered from drug abuse for conturies, although formal Treatment assistance for women has been recognized as important only during the past few decades. The nature and underlying reasons for women's drug abuse differ from men’s behavior in many ways. It is finally understood that research on men will not simply translate into effective solutions for women as well. Here deal with the many issues that can arise in working with disabled women suffered from drug abuse because biologically, Culturally, and socially, their experience is different from that of men and other women and key theme For this discourse is that a woman who suffered from drug abuse is first and foremost a woman. Disabled women also have specific issues that must acknowledge and incorporate into the counseling, social work and other experince, so, here review is based on more than 25 years of the collective experience and firsthand knowledge of Monique Cohen and their Counselors at The CASPAR outpatient Clinic in Cambridge, Massachusett (2000 about women with drug abuse and alcoholism. The clinic Provides omprehensive substance abuse treatment to Individuals and Families struggling with either one or multiple addictions.


    Directory of Open Access Journals (Sweden)

    T. V. Korotaev


    Full Text Available soriatic arthritis (PsA is a chronic inflammatory disease of the joints, spine and entheses from a group of spondyloarthritis (SpA, which is usually observed in patients with psoriasis (Ps. The diagnosis of PsA is based on the CASPAR criteria for psoriatic arthritis. The disease results from interactions between genetic, immunological and environmental factors. The main clinical manifestations of PsA include peripheral arthritis, enthesitis, dactylitis, and spondylitis. PsA must be differentiated from rheumatoid arthritis, gout, reactive arthritis, osteoarthritis, and ankylosing spondylitis. Due to the fact that PsA is a clinically heterogeneous disease, its activity is assessed using complex indices, by taking into account that the patient has arthritis, enthesitis, dactylitis, and spondylitis. The goal of treatment for PsA is to achieve remission or minimal activity of the main clinical manifestations of the disease, to slow down or prevent radiographic progression, to increase life expectancy and quality of life in the patients, and to reduce the risk of comorbidities, which is achieved through a wide range of drugs of different classes. Therapy should be chosen based on the clinical manifestations of PsA and comorbidities in the patients. 

  3. Pilot monitoring program: geologic input for the hillslope component (includes a discussion of Caspar Creek geology and geomorphology) (United States)

    T. E. Spittler


    The California Department of Conservation, Division of Mines and Geology (DMG) is submitting this report and accompanying maps to the California Department of Forestry and Fire Protection (CDF) to fulfill Interagency Agreement number 8CA38400, Pilot Monitoring Program -- Geologic Input for the Hillslope Component. Under this agreement, DMG has assisted CDF in the...

  4. Performance enhanced headgear: a scientific approach to the development of protective headgear. (United States)

    McIntosh, A; McCrory, P; Finch, C F


    There is a continuing debate about the performance of protective headgear in rugby union, rugby league, and Australian rules football. To examine the impact energy attenuation performance of foam that could be incorporated into headgear and examine the performance of prototypes of modified headgear. Impact tests were conducted on polyethylene foams and protective headgear. Free fall drop tests with a rigid headform on to a flat rigid anvil were conducted. Resultant headform acceleration was measured. Means of the headform acceleration maxima for repeat tests were calculated. Tests on polyethylene foam indicated that an increase in thickness from 10 mm to 16 mm would improve headgear performance. These modifications were incorporated in part into two headgear models: the Albion Headpro and the Canterbury brand Body Armour honeycomb headgear. The headgear tests show that significant reductions in headform acceleration were achieved by increasing the foam density and thickness. Mean headform acceleration maxima for the 16 mm thick modified rugby headgear was about 25% of that of standard headgear for lateral impact 0.3 and 0.4 m drop heights and 27% for the centre front 0.3 m drop tests. At these impacts, the headform acceleration for the modified rugby headgear was below 200 g. Significant improvements in impact energy attenuation performance are possible with small design changes. Whether these are sufficient to reduce the rate or severity of concussion in rugby and Australian rules football can only be shown by formal prospective studies on the field.

  5. Biological parameters and fertility life table of Aphis forbesi Weed, 1889 (Hemiptera: Aphididae on strawberry

    Directory of Open Access Journals (Sweden)

    E. S. Araujo

    Full Text Available Abstract This study provides the first contribution of the biology and life table of Aphis forbesi Weed, 1889 (Hemiptera: Aphididae, an important strawberry pest throughout the world. This species lives in the crown and leaf petioles of the plant. It is difficulty to rear this species in laboratory due to protocooperation with ants observed only in the field. We studied the life cycle of A. forbesi on the leaves of the Albion strawberry cultivar at 25 ± 2 °C, 60 ± 10% relative humidity, and a 12-h photophase. The experiment was randomised with 100 replicates. The parameters of the fertility life table were calculated using TabVida. In the population studied, 25% and 46% had four and three instars, respectively. A mean of 1.43 nymphs per female per day was generated. The mean reproductive period was seven days and the mean longevity was 10 days. In every 11 days there is a generation of A. forbesi, where each female has the potential to generate between 6 to 9 individuals daily, increasing its population by 1.2 times. The average life cycle was 16.8 days. High viability observed in all instars and the resulting values of R0, rm and λ suggest that A. forbesi has the capacity to increase their numbers in a short period of time, while generating high populations in strawberry crops, requiring differential management.

  6. Berries grown in Brazil: anthocyanin profiles and biological properties. (United States)

    Chaves, Vitor C; Boff, Laurita; Vizzotto, Márcia; Calvete, Eunice; Reginatto, Flávio H; Simões, Cláudia Mo


    Phytochemical profiles of two Brazilian native fruits - pitanga (red and purple) and araçá (yellow and red) - as well as strawberry cultivars Albion, Aromas and Camarosa, blackberry cultivar Tupy and blueberry cultivar Bluegen cultivated in Brazil were characterized for total phenolic content and total anthocyanin content by liquid chromatography coupled to a photodiode array and a quadrupole time-of-flight mass spectrometer. Radical scavenging, antiherpes and cytotoxic activities of these berry extracts were also evaluated. Blueberry presented the highest total anthocyanin content (1202 mg cyanidin-O-glucoside equivalents kg -1 fresh fruit), while strawberry cultivar Aromas presented the highest total phenolic content (13 550 mg gallic acid equivalents kg -1 fresh fruit). Liquid chromatographic-mass spectrometric analysis resulted in the identification of 21 anthocyanins. To the best of our knowledge this is the first report of cyanidin-O-glucoside in yellow and red Araçá fruit and the first time eight anthocyanins have been reported in pitanga fruits. DPPH and ABTS assays showed that blueberry cultivar Bluegen, blackberry cultivar Tupy and pitanga (red and purple) showed the most promising antiradical activities, respectively. No relevant cytotoxicity against three cancer cell lines or antiherpes activity was detected under the experimental conditions tested. Total anthocyanin content of all fruits had a strong positive correlation with their free radical scavenging activity, suggesting anthocyanins contribute to the antioxidant potential of these fruits. © 2018 Society of Chemical Industry. © 2018 Society of Chemical Industry.

  7. Gypsum as a source of sulfur for strawberry cropsGesso agricola como fonte de enxofre para a cultura do morango

    Directory of Open Access Journals (Sweden)

    Universidade Estadual do Centro-Oeste


    Full Text Available De uma maneira geral, diversos são os estudos sobre a resposta das plantas ao enxofre (S, porém poucos são específicos para a cultura do morangueiro. A exigência por nutrientes e o estado nutricional é um atributo particular de cada espécie e deve ser levada em conta na determinação da demanda nutricional. O objetivo deste trabalho foi avaliar a influência da aplicação de doses S e fósforo (P no desenvolvimento e produtividade do morangueiro. Foi conduzido um experimento em casa de vegetação, em vasos de 2 Kg de solo (Latossolo Bruno, em Guarapuava-PR. O experimento constituiu-se de um fatorial 6 x 2, delineado em blocos ao acaso, com três repetições, sendo seis doses de S: 0, 10, 20, 30, 40 e 50 mg kg-1, na forma de gesso agrícola e duas doses de P: 300 e 600 mg kg-1 de P2O5. Nos vasos foram transplantadas mudas de morango variedade Albion, cultivadas por 170 dias. Os frutos foram colhidos e pesados ao longo do experimento e a parte aérea ao final do experimento. A parte aérea e os frutos foram secos, pesados, moídos e analisados em relação ao teor de S, Ca e P. A produção de frutos de morango foi influenciada pelas doses de S, sendo que a maior produtividade foi alcançada na dose de 60 mg kg-1 de S com aplicação de 300 mg kg-1 de P e na aplicação de 600 mg kg-1 de P combinada com a dose de 37 mg kg-1 de S. There are several studies on plant responses to Sulfur (S, but few are specific to the strawberry crop. The requirement for nutrients and the nutritional status of plants is a particular attribute of each species that should be taken into account when determining the plant’s nutritional demand. The objective of this study was to evaluate the application of S and phosphate (P rates in the development and productivity of strawberry crops. An experiment was conducted in a greenhouse in pots containing 2 kg soil (Oxisol in Guarapuava city of Paraná State. The experiment consisted of a 6 × 2 factorial outlined

  8. Normal Threshold Size of Stimuli in Children Using a Game-Based Visual Field Test. (United States)

    Wang, Yanfang; Ali, Zaria; Subramani, Siddharth; Biswas, Susmito; Fenerty, Cecilia; Henson, David B; Aslam, Tariq


    The aim of this study was to demonstrate and explore the ability of novel game-based perimetry to establish normal visual field thresholds in children. One hundred and eighteen children (aged 8.0 ± 2.8 years old) with no history of visual field loss or significant medical history were recruited. Each child had one eye tested using a game-based visual field test 'Caspar's Castle' at four retinal locations 12.7° (N = 118) from fixation. Thresholds were established repeatedly using up/down staircase algorithms with stimuli of varying diameter (luminance 20 cd/m 2 , duration 200 ms, background luminance 10 cd/m 2 ). Relationships between threshold and age were determined along with measures of intra- and intersubject variability. The Game-based visual field test was able to establish threshold estimates in the full range of children tested. Threshold size reduced with increasing age in children. Intrasubject variability and intersubject variability were inversely related to age in children. Normal visual field thresholds were established for specific locations in children using a novel game-based visual field test. These could be used as a foundation for developing a game-based perimetry screening test for children.

  9. ["Dieu et cerveau, rien que Dieu et cerveau!" Johann Gottfried von Herder (1744-1803) and the neurosciences of this time]. (United States)

    Stahnisch, Frank


    The impact of Johann Gottfried von Herder on the broad spectrum of the history of ideas can hardly be estimated by separate categories derived from individual disciplines. It transcends the spheres of philosophy, theology, historiography and even medical anthropology--also because Herder, unlike many of his contemporary philosophers and hommes de lettres, was particularly interested in the neurophysiological and -anatomical investigations of his time. Herder's universal interest in human learning is reflected in numerous personal contacts to contemporary academic scholars and natural scientists, such as the Swiss theologian Johann Caspar Lavater, whose physiognomic doctrine mapped out a comprehensive research programme on character analysis, or the Mainz anatomist Samuel Thomas von Soemmering. Herder tightly received the latter's assumption about the interplay between the human soul and the anatomy of the brain. In this article, it shall be demonstrated that Herder's neurophilosophy was primarily influenced by a "pandynamic assumption of nature" and that it designated the brain centrally as a "working tool of God"--right between the human faculties of rationality, feeling and bodily development. The attractiveness of this concept to both basic brain research and clinical neurology was a result of his anthropological approach which combined latest developments in the natural sciences with a central perspective on the human sciences.

  10. "Investigations of salmon and steelhead trout downstream migrations in Caspar Creek and Little River, Mendocino County, March-July, 1993" (United States)

    Albert Rodriguez; Weldon Jones


    Abstract - This annual study has been conducted, since 1987, on two coastal streams, in order to observe the different trend patterns of juvenile out migrations for coho salmon and steelhead-trout, figure 1. Analysis of the 1993 trapping season indicates, at Little River, a decrease of steelhead-trout yearlings but an increase in coho ""y+"". Coho...

  11. Uranium potential of precambrian rocks in the Raft River area of northwestern Utah and south-central Idaho. Final report

    International Nuclear Information System (INIS)

    Black, B.A.


    A total of 1214 geochemical samples were collected and analyzed. The sampling media included 334 waters, 616 stream sediments, and 264 rocks. In addition, some stratigraphic sections of Elba and Yost Quartzites and Archean metasedimentary rock were measured and sampled and numerous radiation determinations made of the various target units. Statistical evaluation of the geochemical data permitted recognition of 156 uranium anomalies, 52 in water, 79 in stream sediment, and 25 in rock. Geographically, 68 are located in the Grouse Creek Mountains, 43 in the Raft River Mountains, and 41 in the Albion Range. Interpretation of the various data leads to the conclusion that uranium anomalies relate to sparingly and moderately soluble uraniferous heavy minerals, which occur as sparse but widely distributed magmatic, detrital, and/or metamorphically segregated components in the target lithostratigraphic units. The uraniferous minerals known to occur and believed to account for the geochemical anomalies include allanite, monazite, zircon, and apatite. In some instances samarskite may be important. These heavy minerals contain uranium and geochemically related elements, such as Th, Ce, Y, and Zr, in sufficient quantities to account for both the conspicuous lithologic preference and the generally observed low amplitude of the anomalies. The various data generated in connection with this study, as well as those available in the published literature, collectively support the conclusion that the various Precambrian W and X lithostratigraphic units pre-selected for evaluation probably lack potential to host important Precambrian quartz-pebble conglomerate uranium deposits. Moreover it is also doubted that they possess any potential to host Proterozoic unconformity-type uranium deposits

  12. Magnitude-frequency and Spatial Distribution of Rockfalls in the White Canyon, British Columbia using Terrestrial LiDAR and Microseismic Monitoring Systems (United States)

    van Veen, M.


    Transportation corridors built along natural slopes are subject to frequent rockfall hazards, which can disrupt service and cause damage to infrastructure. Many of these areas exist along the Fraser-Thompson corridor of the CN rail line in Southern British Columbia, particularly in the White Canyon area near Lytton. Here the rail track is situated between the 500 m high slopes and the river, for 2.4 km. The frequency-magnitude relationship between these events and the percentage of rockfalls making it to track level are important components of hazard assessment for these slopes. Traditional methods of collecting rockfall data in this area involve visual inspection by maintenance personnel, however this is an onerous task for such a large slope with frequent rockfall activity, and therefore the rockfall record for this area is often lacking data. Since 2012, high-resolution terrestrial LiDAR (Light detection and ranging) data has been collected for the White Canyon area and analysis of change from sequential LiDAR scans provides detailed data that can't be obtained from traditional rockfall databases, including the magnitude and spatial distribution of rockfall events. While the LiDAR change detection can be useful in identifying rockfall volumes and source zones, it can be difficult to determine the end location of each rockfall and the exact timing of events, as scan data is usually collected over a period of several months. Recently, a microseismic monitoring system has been deployed over a section of the railway track and data is available on time and location of impact at the track level, which permits assessment of the number of rockfalls traversing the whole slope down to track level. This, in combination with data on rockfall magnitudes and source zones obtained from the LiDAR change detection can provide useful information for management of tracks in these hazardous settings and also provides data for calibration of rockfall modelling.

  13. Heavy oil and bitumen : thinking caps on : researchers look at new and greener ways to get at the heavy oil prize

    Energy Technology Data Exchange (ETDEWEB)

    Harrison, L.


    New steam stimulation processes developed by the Alberta Ingenuity Centre for In Situ Energy were discussed. The J-well and gravity-assisted steam stimulation (JAGD) process uses a steam injection well located within the top few metres of a reservoir and a production well comprised of an inclined J-shaped well. JAGD is a transitional cold production-to-thermal-production technology. High pressure steam is used to heat and loosen the bitumen so that it flows to the producer well below. The configuration was designed to cut through mud and shale layers and is suitable for poor quality reservoirs. Simulations conducted in Athabasca reservoirs have demonstrated that JAGD uses approximately 75 per cent of the steam typically used in steam assisted gravity drainage (SAGD) processes. The iSAGD process was designed to reposition parallel wells in order to increase oil mobility. Researchers at the centre are also investigating a catalytic air-stream process called CASPAR which aims to upgrade oil from 10 degrees API to 16 degrees API within the reservoir. The process involves a mixture of heat, catalyst hydrogen, steam, air and water in the reservoir. The process leaves heavier ends of oil underground as well as fractions of greenhouse gases (GHGs). Research is also being conducted on expanding-solvent SAGD (ES-SAGD) a process that adds butane to steam in order to reduce water use. 3 figs.

  14. [The primary stability between manual and robot assisted implantation of hip prostheses: A biomechanical study on synthetic femurs]. (United States)

    Decking, J; Gerber, A; Kränzlein, J; Meurer, A; Böhm, B; Plitz, W


    We investigated the initial stability of cementless stems implanted with robotic milling and conventional manual broaching. Proximally porous structured stems (G2, ESKA-Implants, Luebeck, Germany) were implanted into synthetic femora. In one group, the femoral cavity was prepared by a CT-based robot (CASPAR, URS-Ortho, Germany) with a high-speed milling head. In the other group, femora were rasped manually with broaches. The broaches had 1 mm proximal press-fit, the robotic cavities 1.5 mm. The implants were exposed to 15 000 loading cycles with 1 000 +/- 500 N. The direction of forces on the implant head were chosen to simulate stair climbing. Internal rotation and translation (caudal, dorsal and lateral) of the implants were measured by linear transducers. The robotic group showed significantly less reversible motion regarding translation in caudal, dorsal and lateral directions. The standard deviations of implant motions were smaller in the robotic group. Using robotic preparation of the femur, initial stability was higher and more consistent than with manual broaching, but differences in undersizing of the cavities created in the femur in relation to the implant may have contributed to these differences for the most part. In-vitro-loading experiments focusing on femoral cavities with varying press-fits are recommended before the introduction of new implants or operating procedures.

  15. Study of sodium boiling during a power transient in a heating duct. Investigation carried out within the scope of a study on the safety of fast neutron reactors

    International Nuclear Information System (INIS)

    Seiler, J.-M.


    This work comprises an experimental study and a physical and theoretical interpretation of sodium boiling during a power transient in conditions simulating a power excursion accident in a breeder reactor. The experimental study was performed on an 'out of pile' system with forced sodium convection. It enabled a detailed study to be made of the draining of the heating duct representing a part of a reactor assembly (expansion of the double-phase area on the heating part of the pin). The physical and theoretical interpretation rests on a very simple calculation model solely describing the heat transfers in the duct, assuming that the fluid stays liquid. The extension of the boiling is governed by the initial overheating and the boiling conditioned by thermal inertias of the walls. The extent of the overheating appears to depend on the degree of initial under-saturation. In the absence of overheating, the rate at which the double-phase front moves is controlled by the saturated boiling. This front is well localised when the central temperature gradient is significant. The draining rate is then directly proportional to the growth rate of the temperature in the liquid. The model employed in the CASPAR code for describing power excursion experiments in single liquid phase is described. This code makes it possible to calculate the heat transfers occurring in a forced system by a heating part, a coolant in movement and possibly a part representing an outer cover [fr

  16. Disentangling the response of streamflow to forest management and climate (United States)

    Dymond, S.; Miniat, C.; Bladon, K. D.; Keppeler, E.; Caldwell, P. V.


    Paired watershed studies have showcased the relationships between forests, management, and streamflow. However, classical analyses of paired-watershed studies have done little to disentangle the effects of management from overarching climatic signals, potentially masking the interaction between management and climate. Such approaches may confound our understanding of how forest management impacts streamflow. Here we use a 50-year record of streamflow and climate data from the Caspar Creek Experimental Watersheds (CCEW), California, USA to separate the effects of forest management and climate on streamflow. CCEW has two treatment watersheds that have been harvested in the past 50 years. We used a nonlinear mixed model to combine the pre-treatment relationship between streamflow and climate and the post-treatment relationship via an interaction between climate and management into one equation. Our results show that precipitation and potential evapotranspiration alone can account for >95% of the variability in pre-treatment streamflow. Including management scenarios into the model explained most of the variability in streamflow (R2 > 0.98). While forest harvesting altered streamflow in both of our modeled watersheds, removing 66% of the vegetation via selection logging using a tractor yarding system over the entire watershed had a more substantial impact on streamflow than clearcutting small portions of a watershed using cable-yarding. These results suggest that forest harvesting may result in differing impacts on streamflow and highlights the need to incorporate climate into streamflow analyses of paired-watershed studies.

  17. Thyroid-stimulating immunoglobulins as measured in a reporter bioassay are not detected in patients with Hashimoto’s thyroiditis and ophthalmopathy or isolated upper eyelid retraction

    Directory of Open Access Journals (Sweden)

    Wall JR


    Full Text Available Jack R Wall,1 Hooshang Lahooti,1 Ilhem El Kochairi,1 Simon D Lytton,2 Bernard Champion1 1Department of Medicine, the University of Sydney, Penrith, NSW, Australia; 2SeraDiaLogistics, Munich, Germany Abstract: Although ophthalmopathy is mainly associated with Graves’ hyperthyroidism, milder eye changes are also found in about 25% of patients with Hashimoto’s thyroiditis (HT. The recent finding of negative thyrotropin receptor (TSHR antibodies, as measured in the ­Thyretain™ thyroid-stimulating immunoglobulin (TSI reporter bioassay, in patients with euthyroid Graves’ disease raises the possibility that TSHR antibodies are not the cause of ophthalmopathy in all situations. Here, we have tested serum from patients with HT with and without ophthalmopathy or isolated upper eyelid retraction (UER for TSHR antibodies, using the TSI reporter bioassay and collagen XIII as a marker of autoimmunity against the orbital fibroblast. Study groups were 23 patients with HT with ophthalmopathy, isolated UER, or both eye features and 17 patients without eye signs. Thyretain™ TSI results were expressed as a percentage of the sample-to-reference ratio, with a positive test being taken as a sample-to-reference ratio of more than 140%. Serum collagen XIII antibodies were measured in standard enzyme-linked immunosorbent assay. TSI tests were positive in 22% of patients with HT with no eye signs but in no patient with eye signs. In contrast, TSI tests were positive in 94% of patients with Graves’ ophthalmopathy. Tests were negative in all normal subjects tested. Collagen XIII antibodies were detected in 83% of patients with ophthalmopathy, UER, or both eye features, but in only 30% of patients with no eye signs. Our findings suggest that TSHR antibodies do not play a major role in the pathogenesis of ophthalmopathy or isolated UER in patients with HT. Moreover, the role of TSHR antibodies in the development of ophthalmopathy in patients with Graves

  18. Dating of major normal fault systems using thermochronology: An example from the Raft River detachment, Basin and Range, western United States (United States)

    Wells, M.L.; Snee, L.W.; Blythe, A.E.


    Application of thermochronological techniques to major normal fault systems can resolve the timing of initiation and duration of extension, rates of motion on detachment faults, timing of ductile mylonite formation and passage of rocks through the crystal-plastic to brittle transition, and multiple events of extensional unroofing. Here we determine the above for the top-to-the-east Raft River detachment fault and shear zone by study of spatial gradients in 40Ar/39Ar and fission track cooling ages of footwall rocks and cooling histories and by comparison of cooling histories with deformation temperatures. Mica 40Ar/39Ar cooling ages indicate that extension-related cooling began at ???25-20 Ma, and apatite fission track ages show that motion on the Raft River detachment proceeded until ???7.4 Ma. Collective cooling curves show acceleration of cooling rates during extension, from 5-10??C/m.y. to rates in excess of 70-100??C/m.y. The apparent slip rate along the Raft River detachment, recorded in spatial gradients of apatite fission track ages, is 7 mm/yr between 13.5 and 7.4 Ma and is interpreted to record the rate of migration of a rolling hinge. Microstructural study of footwall mylonite indicates that deformation conditions were no higher than middle greenschist facies and that deformation occurred during cooling to cataclastic conditions. These data show that the shear zone and detachment fault represent a continuum produced by progressive exhumation and shearing during Miocene extension and preclude the possibility of a Mesozoic age for the ductile shear zone. Moderately rapid cooling in middle Eocene time likely records exhumation resulting from an older, oppositely rooted, extensional shear zone along the west side of the Grouse Creek, Raft River, and Albion Mountains. Copyright 2000 by the American Geophysical Union.

  19. Eocene and Miocene extension, meteoric fluid infiltration, and core complex formation in the Great Basin (Raft River Mountains, Utah) (United States)

    Methner, Katharina; Mulch, Andreas; Teyssier, Christian; Wells, Michael L.; Cosca, Michael A.; Gottardi, Raphael; Gebelin, Aude; Chamberlain, C. Page


    Metamorphic core complexes (MCCs) in the North American Cordillera reflect the effects of lithospheric extension and contribute to crustal adjustments both during and after a protracted subduction history along the Pacific plate margin. While the Miocene-to-recent history of most MCCs in the Great Basin, including the Raft River-Albion-Grouse Creek MCC, is well documented, early Cenozoic tectonic fabrics are commonly severely overprinted. We present stable isotope, geochronological (40Ar/39Ar), and microstructural data from the Raft River detachment shear zone. Hydrogen isotope ratios of syntectonic white mica (δ2Hms) from mylonitic quartzite within the shear zone are very low (−90‰ to −154‰, Vienna SMOW) and result from multiphase synkinematic interaction with surface-derived fluids. 40Ar/39Ar geochronology reveals Eocene (re)crystallization of white mica with δ2Hms ≥ −154‰ in quartzite mylonite of the western segment of the detachment system. These δ2Hms values are distinctively lower than in localities farther east (δ2Hms ≥ −125‰), where 40Ar/39Ar geochronological data indicate Miocene (18–15 Ma) extensional shearing and mylonitic fabric formation. These data indicate that very low δ2H surface-derived fluids penetrated the brittle-ductile transition as early as the mid-Eocene during a first phase of exhumation along a detachment rooted to the east. In the eastern part of the core complex, prominent top-to-the-east ductile shearing, mid-Miocene 40Ar/39Ar ages, and higher δ2H values of recrystallized white mica, indicate Miocene structural and isotopic overprinting of Eocene fabrics.

  20. Psoriatic arthritis in patients with psoriasis: evaluation of clinical and epidemiological features in 133 patients followed at the University Hospital of Brasília Artrite psoriásica em pacientes com psoríase: avaliação de características clínicas e epidemiológicas em 133 pacientes atendidos no Hospital Universitário de Brasília

    Directory of Open Access Journals (Sweden)

    Jamille Nascimento Carneiro


    Full Text Available BACKGROUND: Psoriatic arthritis is an inflammatory arthritis associated with psoriasis. Its prevalence in patients with psoriasis varies from 7 to 42% but its exact prevalence is unknown. OBJECTIVES: Considering the lack of national data related to its diagnosis in patients with psoriasis, this study aims to describe the clinical, laboratorial and radiological manifestations of psoriatic arthritis in these patients. METHODS: We evaluated 133 patients with psoriasis, treated as outpatients. These patients were asked to fill in the forms with data about the disease and were submitted to a clinical evaluation by a dermatologist and a rheumatologist. Suspected cases of arthritis were referred for further investigation and were classified according to presence or absence of psoriatic arthritis according to CASPAR criteria. RESULTS: The number of patients with psoriatic arthritis was 47 (35%, 17 of them were new cases. There was no difference between the groups regarding the type of psoriasis, nail involvement, presence of scalp lesions and psoriatic arthritis. Patients with psoriatic arthritis had more enthesitis and dactylitis (46.7% than those without arthritis. CONCLUSIONS: Despite the high prevalence of arthritis found, we know that results from epidemiological studies are variable, which limits their use and interpretation. We conclude that more studies are needed to draw a profile of rheumatic manifestations in our population of psoriasis patients.FUNDAMENTOS: A artrite psoriásica é uma artrite inflamatória associada à psoríase. Sua prevalência nos pacientes com psoríase de 7 a 42% mas sua exata prevalência ainda é desconhecida. OBJETIVOS: Considerando a escassez de dados nacionais relacionados ao seu diagnóstico em pacientes com psoríase o presente estudo visa descrever o quadro clínico, laboratorial e radiológico da doença nesses pacientes. MÉTODOS: Foram avaliados 133 pacientes com diagnóstico de psoríase acompanhados no

  1. Classification and clinical assessment

    Directory of Open Access Journals (Sweden)

    F. Cantini


    Full Text Available There are at least nine classification criteria for psoriatic arthritis (PsA that have been proposed and used in clinical studies. With the exception of the ESSG and Bennett rules, all of the other criteria sets have a good performance in identifying PsA patients. As the CASPAR criteria are based on a robust study methodology, they are considered the current reference standard. However, if there seems to be no doubt that they are very good to classify PsA patients (very high specificity, they might be not sensitive enough to diagnose patients with unknown early PsA. The vast clinical heterogeneity of PsA makes its assessment very challenging. Peripheral joint involvement is measured by 78/76 joint counts, spine involvement by the instruments used for ankylosing spondylitis (AS, dactylitis by involved digit count or by the Leeds dactylitis index, enthesitis by the number of affected entheses (several indices available and psoriasis by the Psoriasis Area and Severity Index (PASI. Peripheral joint damage can be assessed by a modified van der Heijde-Sharp scoring system and axial damage by the methods used for AS or by the Psoriatic Arthritis Spondylitis Radiology Index (PASRI. As in other arthritides, global evaluation of disease activity and severity by patient and physician and assessment of disability and quality of life are widely used. Finally, composite indices that capture several clinical manifestations of PsA have been proposed and a new instrument, the Psoriatic ARthritis Disease Activity Score (PASDAS, is currently being developed.

  2. La transposición como procedimiento artístico en la obra de Peter Rostovsky

    Directory of Open Access Journals (Sweden)

    María Guillermina Fressoli


    Full Text Available Este trabajo indaga la obra del artista Peter Rostovsky, el uso de la transposición  como recurso estético. El caso ofrece un ejemplo de cómo la transposición, en el marco de una tendencia artística que trabaja desde la deconstrucción de diferentes códigos o representaciones culturales, puede devenir un recurso que apela a una referencia compartida con un eventual espectador a fin de componer un discurso poético. Como hipótesis se considera que a través de este procedimiento el artista  reflexiona sobre el desplazamiento de hábitos de visibilidad y percepción en la cultura contemporánea. Este dispositivo, que revisita diferentes obras modernas, formula un enunciado que reflexiona sobre el estatuto de la experiencia en la actualidad. Para desarrollar el problema que el caso plantea se indagará específicamente sobre la serie Ephifany Models en la que el artista reelabora la obra del pintor Caspar Friedrich y, a través de él, los recursos pictóricos del romanticismo alemán. En esa reelaboración Rostovsky traslada el texto decimonónico a una nueva materia significante, este desplazamiento que el artista establece entre el discurso romántico y los recursos del arte contemporáneo comprometen valoraciones sociales y culturales que producen un cambio de sentido del texto fuente constituyendo una transposición.

  3. Incidence of rheumatoid arthritis, psoriatic arthritis and polymyalgia rheumatica in an inland area of central Italy: results of the CAMPO-RHE study. (United States)

    De Socio, Antonia; Perrotta, Fabio Massimo; Grasso, Guido Maria; Lubrano, Ennio


    The aim of the CAMPO-RHE study was to determine the incidence of rheumatoid arthritis (RA), psoriatic arthritis (PsA) and polymyalgia rheumatica (PMR) in patients attending a rheumatologic outpatient's clinic of a new institution in Campobasso, Italy. Campobasso is a small town of approximately 50,000 inhabitants located in the inland territory of central Italy (Molise), and Public Health is managed from a single health authority. In Italy, all citizens are registered with a National Health System of General Practitioner (GP) Physicians. Between the 1 st of June 2014 and the 31 st of May 2016, all consecutive adult patients, sent by a GP, of Campobasso with any diagnosis of musculoskeletal symptoms/signs/complaints were evaluated in a single rheumatology outpatient clinic of our Academic Unit. The clinic represents the first and unique reference for GPs about rheumatic diseases in the territory. Subjects were classified using the 2010 EULAR criteria for RA, the CASPAR criteria for PsA and the 2012 ACR classification criteria for PMR. 1003 adult patients, sent by GPs, with articular or musculoskeletal complaints visited our clinic. Of these, 409 inhabitants of the municipality of Campobasso were evaluated for the study. During the 2-year study period we diagnosed 18, 19 and 12 new cases of RA, PsA and PMR respectively, with a new incident cases rate of 21.4, 22.59 and 27.43/100,000/year on the population at risk. The results of our study could contribute to better define the incidence of these rheumatic diseases classified with the new classification criteria.

  4. Himmelsblau. Bemerkungen zum Thema „Farben“ in Humboldts Alterswerk Kosmos. Entwurf einer physischen Weltbeschreibung

    Directory of Open Access Journals (Sweden)

    Petra Werner


    Full Text Available Articel in German, Abstracts in English and German.For the greater part of his life, Alexander von Humboldt was interested in colour phenomena which he observed in nature. These observations led him to do research into phenomena such as the blue colour of the sky, enigmatic dust and hail, and the colour of plants. Humboldt corresponded with many scientists about the connection between sunlight and the creation of colours, about coloured shadows, the Blue Cave in Capri, the colour of stars, plants etc. Claude-Louis Berthollet developed a model for the composition of a blue colour (Indigo, a technology which was of great importance to the textile industry.The present paper focuses on Humboldt’s interest in the blue colour of the sky, which he shared with artists, writers and scientists like Johann Wolfgang von Goethe, Christian Gottfried Lichtenberg, Caspar David Friedrich and Horace Bénédict de Saussure. During his travels in South America, Humboldt used Saussure’s cyanometer to determine the intensity of the blue colour of the sky. Later he corresponded about this instrument with his friend François Arago who had invented a cyanometer based on chromatic polarisation. While Humboldt was working on his “Cosmos”, Arago explained to his friend the latest results in physics, especially in polarography. Towards the end of his life, Humboldt corresponded with the painter J. G. Schall and admitted that he had somewhat lost his interest in the physical explanation of the blue colour of the sky.

  5. Self-reported interpersonal problems and impact messages as perceived by significant others are differentially associated with the process and outcome of depression therapy. (United States)

    Altenstein-Yamanaka, David; Zimmermann, Johannes; Krieger, Tobias; Dörig, Nadja; Grosse Holtforth, Martin


    Interpersonal factors play a major role in causing and maintaining depression. This study sought to investigate how patients' self-perceived interpersonal problems and impact messages as perceived by significant others are interrelated, change over therapy, and differentially predict process and outcome in psychotherapy of depression. For the present study, we used data from 144 outpatients suffering from major depression that were treated within a psychotherapy study. Interpersonal variables were assessed pre- and posttherapy with the self-report Inventory of Interpersonal Problems-Circumplex Scale (IIP-32; Thomas, Brähler, & Strauss, 2011) and with the informant-based Impact Message Inventory (Caspar, Berger, Fingerle, & Werner, 2016). Patients' levels on the dimensions of Agency and Communion were calculated from both measures; their levels on Interpersonal Distress were measured with the IIP. Depressive and general symptomatology was assessed at pre-, post-, and at 3-month follow-up; patient-reported process measures were assessed during therapy. The Agency scores of IIP and IMI correlated moderately, but the Communion scores did not. IIP Communion was positively associated with the quality of the early therapeutic alliance and with the average level of cognitive-emotional processing during therapy. Whereas IIP Communion and IMI Agency increased over therapy, IIP Distress decreased. A pre-post-decrease in IIP Distress was positively associated with pre-postsymptomatic change over and above the other interpersonal variables, but pre-post-increase in IMI Agency was positively associated with symptomatic improvement from post- to 3-month follow-up. These findings suggest that significant others seem to provide important additional information about the patients' interpersonal style. (PsycINFO Database Record (c) 2017 APA, all rights reserved).

  6. Prevalence and clinical patterns of psoriatic arthritis in Indian patients with psoriasis

    Directory of Open Access Journals (Sweden)

    Ramesh Kumar


    Full Text Available Background: The prevalence and clinical patterns of psoriatic arthritis (PsA varies in different parts of the world and there is little clinical and epidemiological data from the Indian subcontinent. Aims: Our study was designed to evaluate the prevalence and clinical patterns of PsA in Indian patients. Methods: This was a non-interventional, cross-sectional study, in which 1149 consecutive psoriasis patients seen over 1 year were screened for PsA according to classification of psoriatic arthritis (CASPAR criteria. Demographic and disease parameters were recorded including Psoriasis Area and Severity Index (PASI, Nail Psoriasis Severity Index (NAPSI, and number of swollen and tender joints. Results: Among 1149 patients with psoriasis, 100 (8.7% patients had PsA, of which 83% were newly diagnosed. The most common pattern was symmetrical polyarthritis (58%, followed by spondyloarthropathy 49%, asymmetric oligoarthritis (21%, isolated spondyloarthropathy (5%, predominant distal interphalangeal arthritis (3%, and arthritis mutilans (1%. Enthesitis and dactylitis were present in 67% and 26% of cases, respectively. The mean number of swollen and tender joints were 3.63 ± 3.59 (range, 0-22 and 7.76 ± 6.03 (range, 1-26, respectively. Nail changes were present in 87% of the cases. The median PASI and NAPSI of the subjects with PsA was 3.6 and 20, respectively. There was no significant correlation of number of swollen/tender joints with PASI or NAPSI. Conclusion: There is a relatively low prevalence of PsA among Indian psoriasis patients presenting to dermatologists. No correlation was found between the severity of skin and nail involvement and articular disease.

  7. Molecular characterization and experimental host range of an isolate of Wissadula golden mosaic St. Thomas virus. (United States)

    Collins, A M; Mujaddad-ur-Rehman, Malik; Brown, J K; Reddy, C; Wang, A; Fondong, V; Roye, M E


    Partial genome segments of a begomovirus were previously amplified from Wissadula amplissima exhibiting yellow-mosaic and leaf-curl symptoms in the parish of St. Thomas, Jamaica and this isolate assigned to a tentative begomovirus species, Wissadula golden mosaic St. Thomas virus. To clone the complete genome of this isolate of Wissadula golden mosaic St. Thomas virus, abutting primers were designed to PCR amplify its full-length DNA-A and DNA-B components. Sequence analysis of the complete begomovirus genome obtained, confirmed that it belongs to a distinct begomovirus species and this isolate was named Wissadula golden mosaic St. Thomas virus-[Jamaica:Albion:2005] (WGMSTV-[JM:Alb:05]). The genome of WGMSTV-[JM:Alb:05] is organized similar to that of other bipartite Western Hemisphere begomoviruses. Phylogenetic analyses placed the genome components of WGMSTV-[JM:Alb:05] in the Abutilon mosaic virus clade and showed that the DNA-A component is most closely related to four begomovirus species from Cuba, Tobacco leaf curl Cuba virus, Tobacco leaf rugose virus, Tobacco mottle leaf curl virus, and Tomato yellow distortion leaf virus. The putative Rep-binding-site motif in the common region of WGMSTV-[JM:Alb:05] was observed to be identical to that of Chino del tomate virus-Tomato [Mexico:Sinaloa:1983], Sida yellow mosaic Yucatan virus-[Mexico:Yucatan:2005], and Tomato leaf curl Sinaloa virus-[Nicaragua:Santa Lucia], suggesting that WGMSTV-[JM:Alb:05] is capable of forming viable pseudo-recombinants with these begomoviruses, but not with other members of the Abutilon mosaic virus clade. Biolistic inoculation of test plant species with partial dimers of the WGMSTV-[JM:Alb:05] DNA-A and DNA-B components showed that the virus was infectious to Nicotiana benthamiana and W. amplissima and the cultivated species Phaseolus vulgaris (kidney bean) and Lycopersicon esculentum (tomato). Infected W. amplissima plants developed symptoms similar to symptoms observed under field

  8. Morangos produzidos no semiárido de Minas Gerais: qualidade do fruto e da polpa congelados

    Directory of Open Access Journals (Sweden)

    Ariane Castricini


    Full Text Available Resumo O congelamento de morangos inteiros ou em polpa pode fornecer matéria-prima para sua utilização em iogurtes, recheios, coberturas, sorvetes e sucos, fora da safra. Entretanto, ainda que o consumo não seja in natura, a qualidade do produto final deve ser satisfatória. Objetivou-se avaliar a qualidade de morangos produzidos no Semiárido de Minas Gerais, congelados inteiros e em polpa, durante o armazenamento. Frutos das cultivares Tudla, Oso Grande, Albion e Portola foram produzidos em Mocambinho, distrito de Jaíba-MG, após a colheita, foram lavados, embalados (inteiros ou polpa a vácuo e congelados por até 180 dias. Os tratamentos foram constituídos por cultivares (c e dias de armazenamento (d, constituindo fatorial duplo c × d, em que se utilizaram três repetições de 10 frutos por parcela ou três polpas embaladas, para as avaliações de frutos congelados inteiros e em polpa, respectivamente. A intensidade da cor vermelha dos morangos inteiros ou em polpa reduziu-se durante o armazenamento (redução de °hue; quando inteiros, ‘Tudla’, ‘Oso Grande’ e ‘Portola’ foram vermelhos mais claros que ‘Albion’, mas, em polpa, não ocorreu diferença entre ‘Tudla’ e ‘Albion’. Morangos ‘Oso Grande’ armazenados inteiros ou em polpa tiveram maior teor de sólidos solúveis em relação àqueles das demais cultivares, e ‘Portola’, o menor teor e a menor acidez titulável (quando inteiros. ‘Tudla’ apresentou frutos e polpa mais ácidos. Durante o armazenamento de morangos congelados inteiros ou em polpa, produzidos no Semiárido de Minas Gerais, ocorreram modificações nos parâmetros cor, sólidos solúveis e acidez titulável.

  9. Smartphone-based safety planning and self-monitoring for suicidal patients : Rationale and study protocol of the CASPAR (Continuous Assessment for Suicide Prevention And Research) study

    NARCIS (Netherlands)

    Nuij, Chani; van Ballegooijen, Wouter; Ruwaard, Jeroen; de Beurs, Derek; Mokkenstorm, Jan; van Duijn, Erik; de Winter, Remco F.P.; O'Connor, Rory C.; Smit, Jan H.; Riper, Heleen; Kerkhof, Ad


    Background: It remains difficult to predict and prevent suicidal behaviour, despite growing understanding of the aetiology of suicidality. Clinical guidelines recommend that health care professionals develop a safety plan in collaboration with their high-risk patients, to lower the imminent risk of

  10. Report of Secretary of Defense, Caspar W. Weinberger, to the Congress on the FY 1983 Budget, FY 1984 Authorization Request and FY 1983-1987 Defense Programs. (United States)


    although non-aligned, Malaysia , Indonesia, and Singapore support U.S. presence in South- east Asia and allow unhampered U.S. transit of the vital...modernization of obsolete facilities, maintenance of existing facilities, energy conservation, compliance with environmental and OSHA stan- dards, and NATO

  11. Obituary: R(oyal) Glenn Hall, 1921-2004 (United States)

    McCarthy, Dennis Dean


    R. Glenn Hall died on 25 June 2004 following a battle with prostate cancer. His contributions to the determination of the frequency corresponding to an energy level transition in the Cesium atom led to the definition of the length of the second and formed the basis for precise modern timekeeping. Glenn was born on 23 June 1921 in Koloa, Hawaii, and together with a brother and three sisters, grew up in Albion, Michigan. His father was a professor of political science at Albion College. He graduated from Park College in Parkville, Missouri with a degree in mathematics in 1941. He served as a corpsman in the U. S. Navy during World War II, and went on to earn a PhD at the University of Chicago in 1949. Glenn joined the faculty at the University of Chicago as an instructor from 1949 through 1952 and became a research associate there in 1953. While at the U. of Chicago he worked extensively on mass ratios of binary stars, binary star orbits and the determination of stellar parallaxes. In 1953 Glenn came to the U. S. Naval Observatory (USNO) where he became the Assistant Director of the Time Service Division. His early work at the Naval Observatory was related to the determination of Ephemeris Time (ET) from photographic observations of the Moon with respect to background stars. This work provided a time scale more uniform than that based on the Earth's rotation, which was the internationally accepted time scale at the time. As a result, the International Astronomical Union in 1955 redefined the second to be the second as determined from Ephemeris Time. In June 1955, L. Essen and J.V.L. Parry placed in operation a Cesium beam atomic standard at the National Physical Laboratory in Teddington, England. William Markowitz (1907-1998), the director of the Time Service, and Hall together with Essen and Parry then began the work leading to the determination of the frequency of the Cesium atom in terms of the second of the seasonally corrected time scale determined from the

  12. Report of the Secretary of Defense Caspar W. Weinberger to the Congress on the FY 1988/FY 1989 Budget and FY 1988-92 Defense Programs, January 12, 1987. (United States)


    the praise It won from the great English statesman, William Gladstone, as the "most wonderful work ever struck off at a given time by the brain and...enough to sustain one wartime station overseas as well as satisfy training and maintenance needs. Advanced TacticalAir Reconnaissance System ( ATARS ...The ATARS is an umbrella concept for a series of upgrades in tactical reconnaissance capabilities. Major elements of the program include the Tactical

  13. Clinical and immunogenetic characterization in psoriatic arthritis patients. (United States)

    Schneeberger, Emilce Edith; Citera, Gustavo; Rodríguez Gil, Gustavo; Granel, Amelia; Arturi, Alfredo; Rosemffet, Gabriel Marcos; Maldonado Cocco, José Antonio; Berman, Alberto; Spindler, Alberto; Morales, Victor Hugo


    In psoriatic arthritis (PsA), genetic factors play a substantial role in disease susceptibility as well as in its expression. This study aims to determine the distribution of class I and class II HLA antigens in PsA patients and secondly to analyze the influence of genetic factors in the clinical expression of the disease. Consecutive PsA patients (CASPAR criteria) with less than 1 year of disease duration were included. Sociodemographic and clinical data were recorded. Blood samples were obtained, DNA was extracted by polymerase chain reaction (PCR), and class I (A, B, and C) and class II (DR) HLA antigens were determined by oligotyping. A control group of 100 nonrelated healthy controls from the general population served as control. p values were corrected (pc) according to the number of alleles tested. A total of 73 patients were included, 37 were females (50.7 %) with a median disease duration of 72 months (interquartile range (IQR) 24-149). Thirty-three patients (45.2 %) had a family history of psoriasis. When analyzing all the class I and class II HLA antigens, a significantly higher frequency of B38 (odds ratio (OR) 2.95, p = 0.03) and Cw6 (OR 2.78, p = 0.009) was found in PsA patients compared to the control group. On the contrary, the HLA-A11 (OR 0.14, p = 0.04) and B7 (OR 0.31, p = 0.03) were significantly more frequent among healthy controls. Furthermore, B18 was significantly more frequent in patients with early arthritis onset (less than 40 years): seven patients (22.6 %) with early onset compared to two patients (4.8 %) with late onset (p = 0.03). No association between HLA-B27 and spondylitis or HLA-DR4 with polyarticular involvement was observed. The HLA-B38 and Cw6 alleles are associated with a greater PsA susceptibility in Argentine population.


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    T. V. Korotaeva


    Full Text Available The lecture gives basic information about psoriatic arthritis (PsA, a chronic inflammatory disease of the joints, spine, and enthesises from a group of spondyloarthritis. It describes the epidemiology of the disease and considers current ideas on its pathogenesis and factors influencing the development of PsA in psoriatic patients. The classification and clinical forms of PsA are presented. The major clinical manifestations of the disease are indicated to include peripheral arthritis, enthesitis, dactylitis, and spondylitis. The diagnosis of the disease is noted to be established on the basis of its detected typical clinical and radiological signs, by applying the CASPAR criteria. A dermatologist, rheumatologist, and general practitioner screen PsA, by actively detecting complaints, characteristic clinical and radiological signs of damage to the joints, and/or spine, and/or enthesises and by using screening questionnaires. There are data that patients with PsA are observed to be at higher risk for a number of diseases type 2 diabetes mellitus hypertension, coronary heart disease, obesity, metabolic syndrome, inflammatory bowel diseases, etc. The aim of current pharmacotherapy for PsA is to achieve remission or minimal activity of clinical manifestations of the disease, to delay or prevent its X-ray progression, to increase survival, to improve quality of life in patients, and to reduce the risk of comorbidities. The paper considers groups of medicines used to treat the disease, among other issues, information about biological agents (BA registered in the Russian Federation for the treatment of PsA. Most patients are mentioned to show a good response to this therapy option just 3–6 months after treatment initiation; however, some of them develop primary inefficiency. In this case, switching one BA to another is recommended. Some patients using a BA develop secondary treatment inefficiency, which is firstly due to the appearance of

  15. Sensitivity and specificity of plain radiographic features of peripheral enthesopathy at major sites in psoriatic arthritis

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    Helliwell, P.S. [University of Leeds, Academic Unit of Musculoskeletal and Rehabilitation Medicine, Leeds (United Kingdom); Porter, G. [Airedale Hospital NHS Trust, Keighley, West Yorkshire (United Kingdom)


    It has been proposed that the defining difference between rheumatoid arthritis and spondyloarthropathy (including psoriatic arthritis) is the initial pathological lesion where the emphasis in psoriatic arthritis is on the enthesis and in rheumatoid arthritis on the synovium. Classical radiological descriptions of seronegative spondyloarthropathy include enthesopathy at major entheseal insertions characterised by erosions and exuberant new bone formation. In this study, the plain radiographic features of spondyloarthropathy are compared between psoriatic arthritis, other spondyloarthropathies and rheumatoid arthritis. The CASPAR study collected clinical, radiological and laboratory data on 588 patients with physician diagnosed psoriatic arthritis and 525 controls with other inflammatory arthritis, 70% of which had rheumatoid arthritis. Plain radiographs of the pelvis and heels were part of the study protocol, although radiographs of other potential entheseal sites such as the knee, elbow and shoulder, were interpreted if available. All radiographs were read blind by two observers working in tandem. Significant differences in entheseal erosion and entheseal new bone formation were found between psoriatic arthritis, ankylosing spondylitis, undifferentiated spondyloarthropathy, rheumatoid arthritis and other diagnoses (entheseal erosion, chi-squared 20.8, p = 0.008; entheseal new bone formation, chi-squared 24.5, p = 0.001). These differences were mainly due to a higher proportion of these features in ankylosing spondylitis. No differences in the plain radiographic features of enthesopathy were found between psoriatic arthritis and rheumatoid arthritis except in the case of entheseal new bone formation at sites of attachment of inguinal ligament, sartorius and rectus femoris muscles to the ilium (OR 3.01, 95% CI 1.13-8.02). Very few subjects with symptomatic heel involvement had radiographic changes and minimal differences were found between those with and without

  16. Oassi sámi noaidevuođa birra Kaspar Peucera čállosis Commentarius de praecipuis divinationum generibus (Wittenberg 1560: Teakstakritihkalaš hámis jorgalusain ja kommentáraiguin

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    Per Pippin Aspaas


    Full Text Available The text on Sami shamanism in Caspar Peucer’s Commentarius de praecipuis divinationum generibus (Wittenberg 1560: Critical edition, with translation and commentary. Among the sources dealing with the shamanistic skills of the Sami (formerly Lapponian population, a certain text by Kaspar Peucer has so far been little known. This man of extreme learning was the son-in-law of Philip Melanchthon and a Professor at the University of Wittenberg. A true polyhistor, well versed in Medicine, Geography, Astrology, Theology, etc., Peucer included in his chef-d’oeuvre on divination an elaborate description of the shamanism of the so-called Pilappii. The present article offers a critical edition of this text, based on the editions of Wittenberg 1560 (A, 1572 (B, 1580 (C, as well as Zerbst 1591 (D and Frankfurt 1593 (E. In addition to translations into North Sami and Norwegian (see Appendix, some contextualisation is offered, which can be summarised as follows: A similar testimony on shamanism is found in the Historia de gentibus Septentrionalibus by Olaus Magnus (Rome 1555. However, that text is not elaborate enough to prove that Kaspar Peucer has copied his description from him. It is more likely that some student among the considerable number of Swedes, Finns and Norwegians that were immatriculated at Wittenberg University in the years following the Reformation, presented this account to Peucer. Many details in the account make it strikingly similar to Sami folk narratives that have been assembled several centuries later. For example, the description of maritime Sami by Anders Larsen (1870–1949, the Sami book by Johan Turi (published 1910 and Sami songs (joik that were collected by Jacob Fellman in the 1820’s can be compared with Peucer’s account. Peucer himself, however, categorised the shamanism of the Sami as a form of theomanteia, i.e. a form of magic which he considered to originate not from the true God, but from the Devil.

  17. Sensitivity and specificity of plain radiographic features of peripheral enthesopathy at major sites in psoriatic arthritis

    International Nuclear Information System (INIS)

    Helliwell, P.S.; Porter, G.


    It has been proposed that the defining difference between rheumatoid arthritis and spondyloarthropathy (including psoriatic arthritis) is the initial pathological lesion where the emphasis in psoriatic arthritis is on the enthesis and in rheumatoid arthritis on the synovium. Classical radiological descriptions of seronegative spondyloarthropathy include enthesopathy at major entheseal insertions characterised by erosions and exuberant new bone formation. In this study, the plain radiographic features of spondyloarthropathy are compared between psoriatic arthritis, other spondyloarthropathies and rheumatoid arthritis. The CASPAR study collected clinical, radiological and laboratory data on 588 patients with physician diagnosed psoriatic arthritis and 525 controls with other inflammatory arthritis, 70% of which had rheumatoid arthritis. Plain radiographs of the pelvis and heels were part of the study protocol, although radiographs of other potential entheseal sites such as the knee, elbow and shoulder, were interpreted if available. All radiographs were read blind by two observers working in tandem. Significant differences in entheseal erosion and entheseal new bone formation were found between psoriatic arthritis, ankylosing spondylitis, undifferentiated spondyloarthropathy, rheumatoid arthritis and other diagnoses (entheseal erosion, chi-squared 20.8, p = 0.008; entheseal new bone formation, chi-squared 24.5, p = 0.001). These differences were mainly due to a higher proportion of these features in ankylosing spondylitis. No differences in the plain radiographic features of enthesopathy were found between psoriatic arthritis and rheumatoid arthritis except in the case of entheseal new bone formation at sites of attachment of inguinal ligament, sartorius and rectus femoris muscles to the ilium (OR 3.01, 95% CI 1.13-8.02). Very few subjects with symptomatic heel involvement had radiographic changes and minimal differences were found between those with and without

  18. Clinical features and multidisciplinary approaches to dementia care

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    Full Text Available Jacob HG Grand¹, Sienna Caspar², Stuart WS MacDonald11Department of Psychology, University of Victoria, Victoria, BC, Canada; 2Interdisciplinary Graduate Studies, University of British Columbia, Vancouver, BC, CanadaAbstract: Dementia is a clinical syndrome of widespread progressive deterioration of cognitive abilities and normal daily functioning. These cognitive and behavioral impairments pose considerable challenges to individuals with dementia, along with their family members and caregivers. Four primary dementia classifications have been defined according to clinical and research criteria: 1 Alzheimer’s disease; 2 vascular dementias; 3 frontotemporal dementias; and 4 dementia with Lewy bodies/Parkinson’s disease dementia. The cumulative efforts of multidisciplinary healthcare teams have advanced our understanding of dementia beyond basic descriptions, towards a more complete elucidation of risk factors, clinical symptoms, and neuropathological correlates. The characterization of disease subtypes has facilitated targeted management strategies, advanced treatments, and symptomatic care for individuals affected by dementia. This review briefly summarizes the current state of knowledge and directions of dementia research and clinical practice. We provide a description of the risk factors, clinical presentation, and differential diagnosis of dementia. A summary of multidisciplinary team approaches to dementia care is outlined, including management strategies for the treatment of cognitive impairments, functional deficits, and behavioral and psychological symptoms of dementia. The needs of individuals with dementia are extensive, often requiring care beyond traditional bounds of medical practice, including pharmacologic and non-pharmacologic management interventions. Finally, advanced research on the early prodromal phase of dementia is reviewed, with a focus on change-point models, trajectories of cognitive change, and threshold models of

  19. Early change in coping strategies in responsive treatments for borderline personality disorder: A mediation analysis. (United States)

    Kramer, Ueli; Keller, Sabine; Caspar, Franz; de Roten, Yves; Despland, Jean-Nicolas; Kolly, Stéphane


    Difficulty in emotion regulation is a hallmark feature of patients with borderline personality disorder (BPD). Therefore, change in the frequency of certain patients' coping strategies-aiming at emotion regulation-are among the most promising mechanisms of change in treatments for BPD. In parallel, it was highlighted that therapist responsiveness significantly contributed to outcome across treatment approaches (Stiles, 2009). Based on a randomized controlled trial (Kramer et al., 2014), the present process-outcome mediation analysis aims at examining the patient's early change in frequency of coping strategies-in particular the decrease in behavioral forms of coping-as potential mechanism of change in responsive treatments for BPD. A total of 57 patients with BPD were included in the present analysis, out of whom 27 were randomly assigned to a 10-session psychiatric treatment and 30 to a 10-session psychiatric treatment augmented with the responsive intervention of the motive-oriented therapeutic relationship (Caspar, 2007). The 1st, 5th, and 9th session of each therapy were transcribed and analyzed using the Coping Action Pattern Rating Scale (Perry et al., 2005; 171 sessions analyzed in total), a validated observer-rated method for assessing coping strategies in the therapy process. Psychological distress was assessed using the OQ-45 at intake, after Session 5, and after Session 10. The results confirmed a responsiveness effect associated with the motive-oriented therapeutic relationship and showed a significant decrease in frequency of behavioral forms of coping, F(1, 54) = 3.09, p = .05, d = .56, which was not different between the 2 conditions. In addition, we demonstrated that the early decrease in behavioral forms of coping between Sessions 1 and 5 partially mediated the link between the group assignment and the change in psychological distress between Sessions 5 and 10. These results shed light on the centrality of therapist responsiveness in treatments for

  20. Groundwater geochemistry of the Yucatan Peninsula, Mexico: Constraints on stratigraphy and hydrogeology (United States)

    Perry, Eugene; Paytan, Adina; Pedersen, Bianca; Velazquez-Oliman, Guadalupe


    SummaryWe report 87Sr/ 86Sr and ion concentrations of sulfate, chloride, and strontium in the groundwater of the northern and central Yucatan Peninsula, Mexico. Correlation between these data indicates that ejecta from the 65.95 m.y. old Chicxulub impact crater have an important effect on hydrogeology, geomorphology, and soil development of the region. Ejecta are present at relatively shallow subsurface depths in north-central Yucatan and at the surface along the Rio Hondo escarpment in southeast Quintana Roo, where they are referred to as the Albion Formation. Anhydrite/gypsum (and by inference celestite) are common in impact ejecta clasts and in beds and cements of overlying Paleocene and Lower Eocene rocks cored around the margin of the crater. The sulfate-rich minerals that are found in rocks immediately overlying the impact ejecta blanket, may either be partially mobilized from the ejecta layer itself or may have been deposited after the K/T impact event in an extensive pre-Oligocene shallow sea. These deposits form a distinctive sedimentary package that can be easily traced by the Eocene-Cretaceous 87Sr/ 86Sr signal. A distinct Sr isotopic signature and high SO 4/Cl ratios are observed in groundwater of northwestern and north-central Yucatan that interacts with these rocks. Moreover, the distribution of the gypsum-rich stratigraphic unit provides a solution-enhanced subsurface drainage pathway for a broad region characterized by dissolution features (poljes) extending from Chetumal, Quintana Roo to Campeche, Campeche. The presence of gypsum quarries in the area is also consistent with a sulfate-rich stratigraphic "package" that includes ejecta. The distinctive chemistry of groundwater that has been in contact with evaporite/ejecta can be used to trace flow directions and confirms a groundwater divide in the northern Peninsula. Information about groundwater flow directions and about deep subsurface zones of high permeability is useful for groundwater and

  1. [Sciatica. From stretch rack to microdiscectomy]. (United States)

    Gruber, P; Böni, T


    In ancient times as well as in the Middle Ages treatment options for discogenic nerve compression syndrome were limited and usually not very specific because of low anatomical and pathophysiological knowledge. The stretch rack (scamnum Hippocratis) was particularly prominent but was widely used as a therapeutic device for very different spinal disorders. Since the beginning of the nineteenth century anatomical knowledge increased and the advances in the fields of asepsis, anesthesia and surgery resulted in an increase in surgical interventions on the spine. In 1908 the first successful lumbar discectomy was initiated and performed by the German neurologist Heinrich O. Oppenheim (1858-1919) and the surgeon Fedor Krause (1857-1937); however, neither recognized the true pathological condition of discogenic nerve compression syndrome. With the landmark report in the New England Journal of Medicine in 1934, the two American surgeons William Jason Mixter (1880-1958) and Joseph Seaton Barr (1901-1963) finally clarified the pathomechanism of lumbar disc herniation and furthermore, propagated discectomy as the standard therapy. Since then interventions on intervertebral discs rapidly increased and the treatment options for lumbar disc surgery quickly evolved. The surgical procedures changed over time and were continuously being refined. In the late 1960s the surgical microscope was introduced for spinal surgery by the work of the famous neurosurgeon Mahmut Gazi Yasargil and his colleague Wolfhard Caspar and so-called microdiscectomy was introduced. Besides open discectomy other interventional techniques were developed to overcome the side effects of surgical procedures. In 1964 the American orthopedic surgeon Lyman Smith (1912-1991) introduced chemonucleolysis, a minimally invasive technique consisting only of a cannula and the proteolytic enzyme chymopapain, which is injected into the disc compartment to dissolve the displaced disc material. In 1975 the Japanese orthopedic

  2. A comparison of disease burden in rheumatoid arthritis, psoriatic arthritis and axial spondyloarthritis.

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    Brigitte Michelsen

    Full Text Available The main objective of this study was to compare disease burden in rheumatoid arthritis (RA, psoriatic arthritis (PsA and axial spondyloarthritis (ax-SpA.In this cross-sectional study, all the RA (1093, PsA (365 and ax-SpA (333 patients who visited the out-patient clinic of the Hospital of Southern Norway Trust during the year 2013 were included; the RA patients all had a RA diagnosis verified by the treating rheumatologist, the PsA patients all fulfilled the ClASsification for Psoriatic ARthritis (CASPAR criteria and the ax-SpA patients all fulfilled the Assessment of SpondyloArthritis international Society (ASAS classification criteria for ax-SpA. Patient-reported health status, demographic variables, medications, and composite scores of disease activity were assessed. The main analyses were performed using General Linear Models adjusted for age, sex and multiple comparisons. Correlation analyses were performed using Spearman's rho.The reported pain, joint pain, patient's global assessment and fatigue were similar in PsA and ax-SpA, but significantly lower in RA. The 28-joint Disease Activity Score (DAS28 (0.3±0.1, p = 0.003, Clinical Disease Activity Index (CDAI (1.0±0.4, p = 0.028 and Routine Assessment of Patient Index Data 3 (RAPID3 (0.4±0.1, p = 0.004 were all significantly higher in PsA vs. RA. RAPID3 showed moderate to high correlation with DAS28 (rho = 0.521, p<0.001 and CDAI (rho = 0.768, p<0.001 in RA and PsA, and with Bath Ankylosing Spondylitis Disease Activity Index (BASDAI (rho = 0.902, p<0.001 and Bath Ankylosing Spondylitis Functional Index (BASFI (0.865, p<0.001 in ax-SpA and PsA.In conclusion, patient- reported outcome measures were similar in our population of PsA and ax-SpA patients, but significantly lower for the RA patients. Composite disease activity measures were lower in RA than in PsA and ax-SpA, but the magnitude of these differences was small and probably not of clinical significance. Our study indicates that

  3. The shorter the better? A follow-up analysis of 10-session psychiatric treatment including the motive-oriented therapeutic relationship for borderline personality disorder. (United States)

    Kramer, Ueli; Stulz, Niklaus; Berthoud, Laurent; Caspar, Franz; Marquet, Pierre; Kolly, Stéphane; De Roten, Yves; Despland, Jean-Nicolas


    There is little research on short-term treatments for borderline personality disorder (BPD). While the core changes may occur only in long-term treatments, short-term treatments may enable the study of early generic processes of engagement in therapy and thus inform about effective treatment components. It was shown that a 10-session version of a psychiatric treatment was effective in reducing borderline symptoms at the end of this treatment [Kramer, U., Kolly, S., Berthoud, L., Keller, S., Preisig, M., Caspar, F., … Despland, J.-N. (2014). Effects of motive-oriented therapeutic relationship in a ten-session general psychiatric treatment for borderline personality disorder: A randomized controlled trial. Psychotherapy and Psychosomatics, 83, 176-186.]. Also, it was demonstrated in a randomized design that adding the motive-oriented therapeutic relationship (MOTR), following an individualized case formulation based on Plan Analysis, further increased general outcome after session 10 and had a positive effect on the early changes in self-esteem and alliance. The present study focuses on the follow-up period after this initial treatment, examining treatment density and outcomes after 6 months and service utilization after 12 months. Outcome was measured using the OQ-45. Results on a sub-sample of N = 40 patients with available OQ-45 data at follow-up (n = 21 for MOTR-treatment, n = 19 for comparison treatment) showed maintenance of gains over the follow-up period, which did not differ between both conditions. It appeared for this sample that MOTR treatments, while using the same number of sessions, lasted more weeks (i.e., lower treatment density, defined as the number of sessions per week), when compared to the treatments without MOTR. Density marginally predicted symptom reduction at follow-up. Patients in MOTR treatments had a greater likelihood of entering structured psychotherapy after the initial sessions than patients in the comparison

  4. Isolation and sequence analysis of the wheat B genome subtelomeric DNA. (United States)

    Salina, Elena A; Sergeeva, Ekaterina M; Adonina, Irina G; Shcherban, Andrey B; Afonnikov, Dmitry A; Belcram, Harry; Huneau, Cecile; Chalhoub, Boulos


    Telomeric and subtelomeric regions are essential for genome stability and regular chromosome replication. In this work, we have characterized the wheat BAC (bacterial artificial chromosome) clones containing Spelt1 and Spelt52 sequences, which belong to the subtelomeric repeats of the B/G genomes of wheats and Aegilops species from the section Sitopsis. The BAC library from Triticum aestivum cv. Renan was screened using Spelt1 and Spelt52 as probes. Nine positive clones were isolated; of them, clone 2050O8 was localized mainly to the distal parts of wheat chromosomes by in situ hybridization. The distribution of the other clones indicated the presence of different types of repetitive sequences in BACs. Use of different approaches allowed us to prove that seven of the nine isolated clones belonged to the subtelomeric chromosomal regions. Clone 2050O8 was sequenced and its sequence of 119,737 bp was annotated. It is composed of 33% transposable elements (TEs), 8.2% Spelt52 (namely, the subfamily Spelt52.2) and five non-TE-related genes. DNA transposons are predominant, making up 24.6% of the entire BAC clone, whereas retroelements account for 8.4% of the clone length. The full-length CACTA transposon Caspar covers 11,666 bp, encoding a transposase and CTG-2 proteins, and this transposon accounts for 40% of the DNA transposons. The in situ hybridization data for 2050O8 derived subclones in combination with the BLAST search against wheat mapped ESTs (expressed sequence tags) suggest that clone 2050O8 is located in the terminal bin 4BL-10 (0.95-1.0). Additionally, four of the predicted 2050O8 genes showed significant homology to four putative orthologous rice genes in the distal part of rice chromosome 3S and confirm the synteny to wheat 4BL. Satellite DNA sequences from the subtelomeric regions of diploid wheat progenitor can be used for selecting the BAC clones from the corresponding regions of hexaploid wheat chromosomes. It has been demonstrated for the first time

  5. Experiencias en el desarrollo de una aplicación robótica con control de fuerza para taladrado de huesos

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    J.C. Fraile


    Full Text Available Resumen: En los sistemas de cirugía ortopédica asistida por ordenador (CAOS, el taladrado del hueso en la reparación de fracturas de huesos largos (para estabilizarlos con placas, clavos o tornillos es una tarea compleja que el cirujano debe realizar con gran precisión, evitando el calentamiento excesivo del tejido óseo. En la cirugía asistida por robots, se han utilizado principalmente robots industriales (Robodoc, Caspar, Crigos adaptados a ambientes quirúrgicos para ayudar al cirujano en esta tarea. En esta tarea de taladrado de huesos es necesario tener en cuenta varios factores: temperatura del hueso, velocidades de giro y avance de la herramienta de taladrado y fuerzas y pares que actúan sobre el hueso durante su taladrado.Es fundamental el desarrollo de algoritmos de control del robot manipulador para garantizar que las distintas variables que intervienen en el proceso de taladrado tomen los valores adecuados, bajo el control del cirujano, y así lograr una mayor calidad y precisión en la tarea quirúrgica de taladrado del hueso.Desafortunadamente, la mayoría de los robots industriales tienen una arquitectura de control propietaria que impide una fácil implantación de algoritmos de control externos basados en realimentación multisensorial (visión, fuerza.En este artículo se presenta el diseño de una arquitectura de control distribuido y abierto, que se ha implantado sobre el controlador de un robot Staubli. En ella se ha desarrollado una estrategia de control basada en realimentación de fuerza, que permite al cirujano realizar la tarea quirúrgica de taladrado del hueso con elevada precisión. Durante el taladrado con el robot, las fuerzas y pares que actúan sobre el hueso son medidos y utilizados para controlar la velocidad de avance de la herramienta de taladrado, y para controlar la fuerza aplicada al hueso. Se han obtenido resultados experimentales en condiciones de laboratorio con el manipulador equipado con un

  6. Mathematics make microbes beautiful, beneficial, and bountiful. (United States)

    Jungck, John R


    Microbiology is a rich area for visualizing the importance of mathematics in terms of designing experiments, data mining, testing hypotheses, and visualizing relationships. Historically, Nobel Prizes have acknowledged the close interplay between mathematics and microbiology in such examples as the fluctuation test and mutation rates using Poisson statistics by Luria and Delbrück and the use of graph theory of polyhedra by Caspar and Klug. More and more contemporary microbiology journals feature mathematical models, computational algorithms and heuristics, and multidimensional visualizations. While revolutions in research have driven these initiatives, a commensurate effort needs to be made to incorporate much more mathematics into the professional preparation of microbiologists. In order not to be daunting to many educators, a Bloom-like "Taxonomy of Quantitative Reasoning" is shared with explicit examples of microbiological activities for engaging students in (a) counting, measuring, calculating using image analysis of bacterial colonies and viral infections on variegated leaves, measurement of fractal dimensions of beautiful colony morphologies, and counting vertices, edges, and faces on viral capsids and using graph theory to understand self assembly; (b) graphing, mapping, ordering by applying linear, exponential, and logistic growth models of public health and sanitation problems, revisiting Snow's epidemiological map of cholera with computational geometry, and using interval graphs to do complementation mapping, deletion mapping, food webs, and microarray heatmaps; (c) problem solving by doing gene mapping and experimental design, and applying Boolean algebra to gene regulation of operons; (d) analysis of the "Bacterial Bonanza" of microbial sequence and genomic data using bioinformatics and phylogenetics; (e) hypothesis testing-again with phylogenetic trees and use of Poisson statistics and the Luria-Delbrück fluctuation test; and (f) modeling of

  7. Isolation and sequence analysis of the wheat B genome subtelomeric DNA

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    Huneau Cecile


    Full Text Available Abstract Background Telomeric and subtelomeric regions are essential for genome stability and regular chromosome replication. In this work, we have characterized the wheat BAC (bacterial artificial chromosome clones containing Spelt1 and Spelt52 sequences, which belong to the subtelomeric repeats of the B/G genomes of wheats and Aegilops species from the section Sitopsis. Results The BAC library from Triticum aestivum cv. Renan was screened using Spelt1 and Spelt52 as probes. Nine positive clones were isolated; of them, clone 2050O8 was localized mainly to the distal parts of wheat chromosomes by in situ hybridization. The distribution of the other clones indicated the presence of different types of repetitive sequences in BACs. Use of different approaches allowed us to prove that seven of the nine isolated clones belonged to the subtelomeric chromosomal regions. Clone 2050O8 was sequenced and its sequence of 119 737 bp was annotated. It is composed of 33% transposable elements (TEs, 8.2% Spelt52 (namely, the subfamily Spelt52.2 and five non-TE-related genes. DNA transposons are predominant, making up 24.6% of the entire BAC clone, whereas retroelements account for 8.4% of the clone length. The full-length CACTA transposon Caspar covers 11 666 bp, encoding a transposase and CTG-2 proteins, and this transposon accounts for 40% of the DNA transposons. The in situ hybridization data for 2050O8 derived subclones in combination with the BLAST search against wheat mapped ESTs (expressed sequence tags suggest that clone 2050O8 is located in the terminal bin 4BL-10 (0.95-1.0. Additionally, four of the predicted 2050O8 genes showed significant homology to four putative orthologous rice genes in the distal part of rice chromosome 3S and confirm the synteny to wheat 4BL. Conclusion Satellite DNA sequences from the subtelomeric regions of diploid wheat progenitor can be used for selecting the BAC clones from the corresponding regions of hexaploid wheat


    Directory of Open Access Journals (Sweden)

    Salina E.A.


    Full Text Available Three key periods that were accompanied by considerable rearrangements in the B genome of wheat and its progenitor can be considered. The first period covers the period from the divergence of diploid Triticum and Aegilops species from their common progenitor (2.5–6 million years ago to formation of the tetraploid T. diccocoides (about 500 thousand years ago. Significant genomic rearrangements in the diploid progenitor of the B genome, Ae. speltoides (SS genome, involved a considerable amplification of repeated DNA sequences, which led to an increase in the number of heterochromatin blocks on chromosomes relative to other diploid Aegilops and Triticum species. Our analysis has demonstrated that during this period the Spelt1 repeats intensively amplified as well as several mobile elements proliferated, in particular, the genome-specific gypsy LTR-retrotransposon Fatima and CACTA DNA-transposon Caspar. The second period in the B-genome evolution was associated with the emergence of tetraploid (BBAA genome and its subsequent evolution. The third most important event leading to the next rearrangement of the B genome took place relatively recently, 7000–9500 years ago, being associated with the emergence of hexaploid wheat with the genomic formula BBAADD. The evolution of the B/S genome involved intergenomic and intragenomic translocations and chromosome inversions. So far, five rearrangements in the B-genome chromosomes of polyploid wheats has been observed and described; the majority of them took place during the formation and evolution of tetraploid species. The mapping of the S-genome chromosomes and comparison with the B-genome chromosome maps have demonstrated that individual rearrangements pre-existed in Ae. speltoides; moreover, Ae. speltoides is polymorphic for these rearrangements.Chromosome 5B is nearly 870 Mbp (5BL = 580 Mbp and 5BS = 290 Mbp and is known to carry important genes controlling the key aspects of wheat biology, in

  9. The Paradox of Romantic Ekphrasis. Metacritic Discourse, Perception and Imagination in Art Description

    Directory of Open Access Journals (Sweden)

    Renata Gambino


    Full Text Available Ekphrasis is a text genre based on the intertwining of visual and verbal features, involving the processes of both reading, and priming a visual image or a related action. We argue in this study that this genre, which has been object of many disputes and critical claims over the times, is a powerful tool in order to stimulate a particularly intense activation of the reader/listener’s emotions and imagination. This because of the double nature of the inputs triggering more powerfully the embodied simulation by mixing the regime of perception, affection and thought. Ekphrasis is characterized by a “paradoxical nature”, i.e. the fact that the fictional visible qualities of the described artwork disavow the process of visualization by facing the reader/listener with the need of “creating” his own images, by activating a kind of “guided imagination act”. The intertwining of codes determines also a substitution of the description by actions, as described by ancient rhetoricians. The description of actions solicits more powerfully the embodied simulation of the reader/listener. This creates an “in-between” space where what was unthinkable becomes thinkable. Since the afforded cognitive process is overwhelming for the reader/listener, he/she is driven to overcome his/her own cognitive limitations thanks to processes of the imagination that “fills in the gaps” between the known and unknown. We argue that in modern times, starting with Romantics, this process is particularly amplified and ekphrasis becomes a metacritical commentary about the act of imagining, since it induces the reader to complete the description by simulating a personal experience triggered by the rhetorical “vividness” of ekphrasis. This hypothesis will be elucidated by investigating as case-study an ekphrastic text by German author Heinrich von Kleist, who wrote about the revolutionary painting The Monk at the Sea by Caspar David Friedrich. In Kleist’s text

  10. Elemental and Isotopic Tomography at Single-Atom-Scale in 4.0 and 2.4 Ga Zircons (United States)

    Valley, J. W.; Reinhard, D. A.; Snoeyenbos, D.; Lawrence, D.; Martin, I.; Kelly, T. F.; Ushikubo, T.; Strickland, A.; Cavosie, A. J.


    Atom probe tomography can determine identity (mass/charge ratio) and 3-D position of individual atoms in minerals such as zircon. These data provide unique information for understanding the thermal history and mechanisms of mineral reaction and exchange, including radiation damage. Nine needle-shaped specimens ~100 nm in diameter (at the apex) were sampled from 2 zircons by FIB and analyzed with a local-electrode atom probe (LEAP), CAMECA LEAP 4000X HR. The LEAP uses pulsed-laser heating to field evaporate the tip of a zircon needle and accelerates the ions into a position-sensitive TOF-MS. With due care for complex isobaric interferences (molecules, multiple ionizations) and background correction, it is possible to individually identify up to 10E8 atoms/needle (36% detection efficiency) by mass/charge (MRP ~ 1000@ m/n=16Da) and position (X-Y-Z coordinates on 0.2 nm scale) (Kelly & Larson 2012). The 3-D distribution of Pb and Y differ at atom-scale in the 2 zircons. Zircon #1 (4007 Ma, Jack Hills, W. Australia, Cavosie 2005, Ushikubo et al. 2008, Bouvier et al. 2011) is homogeneous in Pb and Y. In contrast, incompatible elements, including Pb and Y, are concentrated in equant 5-10 nm dia. domains, spaced ~50 nm apart in zircon #2 (2438 Ma, Albion-Raft R-Grouse Ck core complex, Utah, Strickland et al. 2011). U is homogeneously distributed in both zircons. The analyzed domains suffered 4-8 x 10E15 α-decay events/mg due to U and Th decay and yet both zircons yield >97% concordant U-Pb ages by SIMS, suggesting annealing of radiation damage during the life of the zircons. The 207-Pb/206-Pb ratios for these nm-scale domains, as measured by LEAP, average 0.17 for the 2.4 Ga Zrc2 (3 needles) and 0.43 for the 4.0 Ga Zrc1 (5 needles). These ratios are less precise (±40% 2σ) due to ultra-small sample size, but are in excellent agreement with values measured by SIMS, 0.1684 and 0.4269, respectively. Thus Pb in both zircons is radiogenic. The Pb-Y-rich domains and lack of

  11. [Man and his fellow-creatures under ethical aspects]. (United States)

    Teutsch, Gotthard M


    's excessive meat consumption as a "cruel necessity". Klaus Peter Joern also enters into Schweitzer's fundamental argumentation in his "A good bye to the disparagement of our fellow creatures". Quotation: "It just cannot go on that Christianity lets the validity of the commandment of love end at the behaviour towards humans, simply because that is the tradition. We rather have to, in this instance, deny the authority of the Bible it's due respect, as this has deemed Schweitzer already inevitable." The killing of animals, irrespective of the motives, remains a critical issue in the understanding (or the lack thereof) with regard to the dignity of all creation. Manuela Linnemann, Charles Patterson, Evelyn Ofensberger and the German Veterinary Association for the Protection of Animals have dealt with this issue extensively. As always, more space is taken up by publications dealing with legal questions and developments. In particular, the conference report of the Protestant Academy at Bad Boll should be mentioned "Animal protection on good constitution". Contributions to this report, edited by the academy, include Hans Georg Kluge's "The governmental aim 'animal protection' and it's implementation in jurisdiction" and Johannes Caspar's "effects of the governmental goal 'animal protection' in the protected area of unconditional fundamental rights". Regarding animal experiments, the last two position papers commissioned by the Foundation for animal-free research (FFVFF), dealing with perspectives of 3R research, have been published within the period of time covered by this report. Alternatives in basic research (with once again rising numbers of experimental animals) and in biomedical education are the themes dealt with by Franz P. Gruber and his co-authors Thomas Hartung and David Dewhurst.

  12. Book Review: Beitraege zur Astronomiegeschichte, Band 5 (Acta Historica Astronomiae Vol. 15) (United States)

    Duerbeck, H. W.; Dick, W. R.; Hamel, J.


    The 15th volume of the Acta Historica Astronomiae is at the same time the fifth collection of essays on the history of astronomy (Beitraege zur Astronomiegeschichte, Band 5), edited by the historians of astronomy W.R. Dick (Potsdam) and J. Hamel (Berlin). Besides a few short notices and book reviews, the book contains 11 major articles, which deal with astronomical topics covering the time from the 16th to the 20th centuries. The first article, on the analysis and interpretation of historical horoscopes as a source of the history of science, is based on the inaugural lecture of its author, Guenther Oestmann. After a general introduction, which deals with the principles of horoscope making, the author discusses the horoscope of Count Heinrich Ranzau (1526-1598), the Danish governor of Schleswig-Holstein, who was a friend of Tycho Brahe. Oestmann shows that the astronomical-mathematical basis of such a horoscope can be reconstructed and interpreted. However, it is hardly possible to gain an insight in the process how the interpretation of a horoscope was done in detail. The second and third articles, by Franz Daxecker, deal with Athanasius Kircher and Christoph Scheiner, two catholic astronomers of the 17th century. Kircher's Organum Mathematicum is a calculating device that can be used in the fields of arithmetic, geometry, chronology, astronomy, astrology and others. The author provides extracts of the description of the Organum taken from a book by Caspar Schott, which deal with chronology and astronomy. A photograph of the Organum indicates that this tool consists of a set of tables glued on wooden or cardboard, but details of its contents and applications remain pretty obscure for the reader - a few elaborated examples would have been helpful. The second paper deals with the life of Christoph Scheiner SJ, the co-discoverer of sunspots (next to Galileo), after leaving Rome in 1633 - the year of the Galileo trial. Scheiner spent his later years in the Austrian and