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Sample records for lycopodium annotinum tom

  1. Phyllotaxis diversity in Lycopodium clavatum L. and Lycopodium annotinum L.

    Directory of Open Access Journals (Sweden)

    Edyta Gola

    2014-01-01

    Full Text Available In shoots of Lycopodium microphyllous phyllotaxis is extremely diverse. 24 various patterns were found in anisotomous L. clavatum and "only" 11 in isotomous L. annotinum. Spiral patterns expressed by k:(k+1 parastichy numbers were present together with typically whorled k:k patterns. In both species k number was higher in plagiotropic shoots than in orthotropic. It was also higher in L. clavatum than in L. annotinum. In the first species phyllotactic spectrum was wider with many patterns almost equally frequent, whereas narrow spectrum of L. annotinum showed clear dominance of only one pattern. The patterns, which are the most frequent in other plants, such as Fibonacci or Lucas, were uncommon in studied Lycopodium species. Discontinuous phyllotactic transitions occurred typically in two locations on the shoot: just below the dichotomic branching or above the borders, that separate the annual increments of the axis. Transitions were moderately frequent occurring in more than 7% of developmentally independent shoot segments. Dichotomous branching, resulting in variable shoot diameter, seasonal fluctuations of growth as well as a small size of microphylls relative to the shoot circumference are proposed to be the main factors contributing to the high phyllotactic diversity in studied species.

  2. The dynamics of stiff clubmoss Lycopodium annotinum L. patches in clumps of trees left on the clear-cutting in pine forest Leucobryo-Pinetum

    Directory of Open Access Journals (Sweden)

    Bogdanowicz Monika

    2015-03-01

    Full Text Available Clumps of trees left on the clear-cuttings have an important role in protecting populations of endangered plant species against destruction during silviculture activities. The aim of this study is to describe the changes in the area of the Lycopodium annotinum patches. The area of L. annotinum patch in clump of trees, have been significantly reduced during 5 years after clear-cut. In the first year of the observations, the studied population occupied an area of 69.8 m2 whereas in 2012, it was only 37.5 m2. Most of the shoots were withered away on the south side of the clump. The probable reason was too strong insolation. Shoots that survived were located in the north part of the clump – shielded by young trees and shrubs layer. At this time, the control patch of L. annotinum located inside the forest increased its area. Before the clear-cuttings, the annual growth of vertical shoots of clubmoss was higher in the patch located in future tree clump. After the clear-cutting, growth of shoots in this patch was shorter than in patch located all the time inside the forests. The most effective growth was observed in the third studied patch located in the clear-cutting border. The explanation for this phenomenon could be the higher humidity of habitat on this site. Clumps of trees left after the clear-cutting contribute to the protection of endangered populations, but do not eliminate the significant microhabitat changes. The clubmoss patches located in moist habitats are more likely to survive even if they are partially exposed to the sunlight.

  3. Lycopodium alkaloids from Palhinhaea cernua

    Energy Technology Data Exchange (ETDEWEB)

    Zhao, Fu-Wei [Graduate University of Chinese Academy of Sciences, Beijing (China); Luo, Ji-Feng; Wang, Yue-Hu, E-mail: wangyuehu@mail.kib.ac.cn [Key Laboratory of Economic Plants and Biotechnology, Kunming Institute of Botany, Chinese Academy of Sciences (China); Sun, Qian-Yun; Yang, Fu-Mei [Key Laboratory of Chemistry for Natural Products, Guizhou Province and Chinese Academy of Sciences (China); Liu, Fang [College of Landscape and Horticulture, Yunnan Agricultural University (China); Long, Chun-Lin, E-mail: long@mail.kib.ac.cn [College of Life and Environmental Sciences, Minzu University of China, Beijing, (China)

    2012-07-01

    Two new Lycopodium alkaloids, acetyllycoposerramine M and palcernine A were isolated from whole plant extracts of Palhinhaea cernua L. together with ten previously identified compounds. The structures of the new compounds were elucidated by spectroscopic methods and single-crystal X-ray diffraction analyses using the Flack parameter. (author)

  4. Acetylcholinesterase inhibitory activity of lycopodane-type alkaloids from the Icelandic Lycopodium annotinum ssp. alpestre

    DEFF Research Database (Denmark)

    Halldórsdóttir, Elsa Steinunn; Jaroszewski, Jerzy W; Olafsdottir, Elin Soffia

    2010-01-01

    determined. Conformation of acrifoline was characterized using NOESY spectroscopy and molecular modelling. The isolated alkaloids were evaluated for their in vitro inhibitory activity against acetylcholinesterase and butyrylcholinesterase. Ligand docking studies based on mutated 3D structure of Torpedo...

  5. PRIMER REGISTRO DE LYCOPODIUM CLAVATUM (LYCOPODIACEAE PARA URUGUAY

    Directory of Open Access Journals (Sweden)

    Héctor A. González

    2016-01-01

    Full Text Available Se registra por primera vez para la flora uruguaya a Lycopodium clavatum (Lycopodiaceae, hallada en los departamentos de Durazno y Maldonado. Este nuevo registro extiende su área de distribución, es- tableciendo las localidades situadas en el centro y este del Uruguay como el límite distribucional austral de Lycopodium s. str. Se presenta una descripción diagnóstica, un mapa de distribución en el país, así como la ilustración de la especie y fotografías del hábitat.

  6. Pyrolysis and combustion kinetics of lycopodium particles in thermogravimetric analysis

    Institute of Scientific and Technical Information of China (English)

    Seyed Alireza Mostafavi; Sadjad Salavati; Hossein Beidaghy Dizaji; Mehdi Bidabadi

    2015-01-01

    Biomass is a kind of renewable energy which is used increasingly in different types of combustion systems or in the production of fuels like bio-oil. Lycopodium is a cellulosic particle, with good combustion properties, of which microscopic images show that these particles have spherical shapes with identical diameters of 31 μm. The measured density of these particles is 1.0779 g/cm2. Lycopodium particles contain 64.06% carbon, 25.56% oxygen, 8.55% hydrogen and 1.83% nitrogen, and no sulfur. Thermogravimetric analysis in the nitrogen environment indicates that the maximum of particle mass reduction occurs in the temperature range of 250−550 °C where the maximum mass reduction in the DTG diagrams also occurs in. In the oxygen environment, an additional peak can also be observed in the temperature range of 500−600 °C, which points to solid phase combustion and ignition temperature of lycopodium particles. The kinetics of reactions is determined by curve fitting and minimization of error.

  7. TOMS Absorbing Aerosol Index

    Data.gov (United States)

    Washington University St Louis — TOMS_AI_G is an aerosol related dataset derived from the Total Ozone Monitoring Satellite (TOMS) Sensor. The TOMS aerosol index arises from absorbing aerosols such...

  8. Radiative Structures of Lycopodium-Air Flames in Low Gravity

    Science.gov (United States)

    Berlad, A. L.; Tangirala, V.; Ross, H.; Facca, L.

    1989-01-01

    Initially uniform clouds of fuel particulates in air sustain processes which may lead to particle cloud nonuniformities. In low gravity, flame-induced Kundt's Tube phenomena are observed to form regular patterns of nonuniform particle concentrations. Irregular patterns of particle concentrations also are observed to result from selected nonuniform mixing processes. Low gravity flame propagation for each of these classes of particle cloud flames has been found to depend importantly on the flame-generated infrared radiative fields. The spatial structures of these radiative fields are described. Application is made for the observed clases of lycopodium-air flames.

  9. Phytochemical analysis and antioxidant capacity of Lycopodium clavatum Linn. from Lake Sebu, South Cotabato, Philippines

    Science.gov (United States)

    Descallar, Angem L.; Nuñez, Maria Pamela S.; Cabrera, Maria Luisa N.; Martin, Tres Tinna B.; Obemio, Christine Dawn G.; Lañojan, Rhumer S.

    2017-01-01

    Lycopodium clavatum or locally known as "lumot" is one of the many plants used in the traditional system of medicine here in the Philippines. It has been known that this plant was used for body pains and "facial wipes" recognizing its anti-aging potential by the Obo community in Lake Sebu, South Cotabato. However, there is a lack of sufficient data on its phytochemical components and medicinal properties. Thus, this study is conducted to determine the secondary metabolites present and its antioxidant property of the decoction and ethanolic extracts of Lycopodium clavatum Linn. Free radical scavenging activity of Lycopodium clavatum Linn. was determined by in vitro 2, 2-diphenyl-1-picrylhydrazyl (DPPH) method. Antioxidant activities were observed which may be due to the presence of alkaloids, steroids, and flavonoids in both decoction and ethanolic extracts.

  10. Unified Synthesis of 10-Oxygenated Lycopodium Alkaloids: Impact of C10-Stereochemistry on Reactivity.

    Science.gov (United States)

    Saha, Mrinmoy; Li, Xin; Collett, Nathan D; Carter, Rich G

    2016-07-15

    The pronounced impact of the C10 stereochemistry on the successful construction of a polycyclic Lycopodium alkaloid scaffold has been explored. A wide range of reaction conditions and functionality were investigated to control a keto sulfone Michael addition to construct the C7-C12 linkage. An unexpected, overriding impact of the C10 stereochemistry in stereoselectivity and reaction rate in the Michael addition was observed. Furthermore, divergent reactivity of a conformationally accelerated, intramolecular Mannich cyclization based on the C10 stereochemistry was discovered. The successful execution of this synthetic route resulted in the total synthesis of all three known 10-oxygenated Lycopodium alkaloids: 10-hydroxylycopodine, paniculine, and deacetylpaniculine.

  11. Lycopodium: growth form, morphology, and sustainability of a non-timber forest product

    Science.gov (United States)

    Elizabeth A. Nauertz; John C. Zasada

    2001-01-01

    Several species of Lycopodium or clubmoss belong in the category of non-timber forest products and are often gathered for a variety of traditional uses. It is important to evaluate baseline information for these species, such as abundance and frequency of occurrence, before making any management decision. In addition, understanding the biology of the...

  12. Researcher Interview: Tom Hudson

    Science.gov (United States)

    Tom Hudson, M.D., President and Scientific Director of the Ontario Institute for Cancer Research, describes the International Cancer Genome Consortium (ICGC), which brings together cancer genomic data and research from across the world.

  13. A two-dimensional analytical model of laminar flame in lycopodium dust particles

    Energy Technology Data Exchange (ETDEWEB)

    Rahbari, Alireza [Shahid Rajaee Teacher Training University, Tehran (Iran, Islamic Republic of); Shakibi, Ashkan [Iran University of Science and Technology, Tehran (Iran, Islamic Republic of); Bidabadi, Mehdi [Combustion Research Laboratory, Narmak, Tehran (Iran, Islamic Republic of)

    2015-09-15

    A two-dimensional analytical model is presented to determine the flame speed and temperature distribution of micro-sized lycopodium dust particles. This model is based on the assumptions that the particle burning rate in the flame front is controlled by the process of oxygen diffusion and the flame structure consists of preheat, reaction and post flame zones. In the first step, the energy conservation equations for fuel-lean condition are expressed in two dimensions, and then these differential equations are solved using the required boundary condition and matching the temperature and heat flux at the interfacial boundaries. Consequently, the obtained flame temperature and flame speed distributions in terms of different particle diameters and equivalence ratio for lean mixture are compared with the corresponding experimental data for lycopodium dust particles. Consequently, it is shown that this two-dimensional model demonstrates better agreement with the experimental results compared to the previous models.

  14. "Tom Byers: The New Colossus"

    DEFF Research Database (Denmark)

    Dalsgaard, Inger Hunnerup

    2013-01-01

    Educational and social welcome strategies to American Society and Culture: SUSI director Tom Byers, The Statue of Liberty and Emma Lazarus' "New Colossus"......Educational and social welcome strategies to American Society and Culture: SUSI director Tom Byers, The Statue of Liberty and Emma Lazarus' "New Colossus"...

  15. "Tom Byers: The New Colossus"

    DEFF Research Database (Denmark)

    Dalsgaard, Inger Hunnerup

    2013-01-01

    Educational and social welcome strategies to American Society and Culture: SUSI director Tom Byers, The Statue of Liberty and Emma Lazarus' "New Colossus"......Educational and social welcome strategies to American Society and Culture: SUSI director Tom Byers, The Statue of Liberty and Emma Lazarus' "New Colossus"...

  16. Development of porous ceramics by lycopodium using uniaxial pressing and sintering

    Directory of Open Access Journals (Sweden)

    Rita Serzane

    2010-12-01

    Full Text Available In this work microporous hydroxyapatite (HAp ceramics were fabricated using lycopodium as a porosifier. The samples were produced by uniaxial pressing and then heating at high temperatures, 1100°C and 1200°C, to burn-out porogens and sintering. The obtained samples had porosity over the variable range of 12 to 45% with different pore size ranging from 0.2 to 25 µm. Chemical and physical characterization was determined by scanning electron microscopy (SEM, X-ray diffraction (XRD, Fourier transform infrared spectroscopy (FTIR and bending strength measurements. The bending strength of the prepared samples was in the range of 1.97–21.81 MPa.

  17. Palhicerines A-F, Lycopodium alkaloids from the club moss Palhinhaea cernua.

    Science.gov (United States)

    Tang, Yu; Xiong, Juan; Zou, Yike; Zhang, Hai-Yan; Hu, Jin-Feng

    2016-11-01

    Four fawcettimine-type (palhicerines A-D, resp.) and two lycopodine-type (palhicerines E and F) Lycopodium alkaloids together with twenty known ones were isolated from the whole plant of Palhinhaea cernua. The structures and absolute configurations of the palhicerines A-F were determined by extensive spectroscopic methods, single-crystal X-ray diffraction analyses, chemical transformation, and electronic circular dichroism (ECD) calculations or induced electronic circular dichroism (IECD) spectra. Among the isolates, the new C/D-ring of the palhicerines A-C (trans-fused fawcettimine-type alkaloids) are rare, and each possesses a β-oriented C-16 methyl group and a distinctive tertiary methoxy group at C-13. Chemotaxonomy for differentiating species in the genus Palhinhaea is briefly discussed.

  18. 75 FR 69470 - Tele Atlas North America, Inc., Currently Doing Business as Tom Tom Including Off-Site Workers...

    Science.gov (United States)

    2010-11-12

    ... Employment and Training Administration Tele Atlas North America, Inc., Currently Doing Business as Tom Tom... Doing Business as Tom Tom, Concord, MA; Tele Atlas North America, Inc. Currently Doing Business as Tom Tom, Detroit, MI; Tele Atlas North America, Inc. Currently Doing Business as Tom Tom, Redwood, CA...

  19. Implementing Deep Inference in Tom

    OpenAIRE

    Kahramanogullari, Ozan; Moreau, Pierre-Etienne; Reilles, Antoine

    2005-01-01

    ISSN 1430-211X; The calculus of structures is a proof theoretical formalism which generalizes sequent calculus with the feature of deep inference: in contrast to sequent calculus, the calculus of structures does not rely on the notion of main connective and, like in term rewriting, it permits the application of the inference rules at any depth inside a formula. Tom is a pattern matching processor that integrates term rewriting facilities into imperative languages. In this paper, relying on th...

  20. A Type System for Tom

    Directory of Open Access Journals (Sweden)

    Claude Kirchner

    2010-03-01

    Full Text Available Extending a given language with new dedicated features is a general and quite used approach to make the programming language more adapted to problems. Being closer to the application, this leads to less programming flaws and easier maintenance. But of course one would still like to perform program analysis on these kinds of extended languages, in particular type checking and inference. In this case one has to make the typing of the extended features compatible with the ones in the starting language. The Tom programming language is a typical example of such a situation as it consists of an extension of Java that adds pattern matching, more particularly associative pattern matching, and reduction strategies. This paper presents a type system with subtyping for Tom, that is compatible with Java's type system, and that performs both type checking and type inference. We propose an algorithm that checks if all patterns of a Tom program are well-typed. In addition, we propose an algorithm based on equality and subtyping constraints that infers types of variables occurring in a pattern. Both algorithms are exemplified and the proposed type system is showed to be sound and complete.

  1. In vitro biological activity screening of Lycopodium complanatum L. ssp. chamaecyparissus (A. Br.) Doll.

    Science.gov (United States)

    Orhan, Ilkay; Ozcelik, Berrin; Aslan, Sinem; Kartal, Murat; Karaoglu, Taner; Sener, Bilge; Terzioglu, Salih; Iqbal Choudhary, M

    2009-01-01

    This article reports the results of selected biological activities, including anticholinesterase, antioxidant, antibacterial, antifungal and antiviral properties, of the petroleum ether, chloroform and methanol extracts as well as the alkaloid fraction of Lycopodium complanatum L. ssp. chamaecyparissus (A. Br.) Doll (LCC, Lycopodiaceae) growing in Turkey. Anticholinesterase effect of the extracts was tested against both acetylcholinesterase (AChE) and butyrylcholinesterase (BChE) at concentrations of 0.2 and 1 mg mL(-1) using microplate-reader assay based on Ellman method. Antioxidant activity of the LCC extracts was evaluated by 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical-scavenging method at 0.2 mg mL(-1) using microplate-reader assay. Both DNA virus Herpes simplex (HSV) and RNA virus Parainfluenza (PI-3) were employed for antiviral assessment of LCC exracts using Madin-Darby Bovine Kidney and Vero cell lines. Antibacterial and antifungal activities of the extracts were screened against the bacteria: Escherichia coli, Pseudomonas aeruginosa, Proteus mirabilis, Acinobacter baumannii, Klebsiella pneumoniae, Staphylococcus aureus, Bacillus subtilis as well as the fungi: Candida albicans and C. parapsilosis. Only the petroleum ether extract of LCC possessed remarkable activity against both AChE and BChE at 1 mg mL(-1) (76.5 and 69.6%, respectively), whereas LCC extracts showed low free radical-scavenging activity. All of the extracts were found to be more effective against the ATCC strains than isolated ones, particularly S. aureus, while the extracts had moderate antifungal activity. On the other hand, we found that only the petroleum ether extract was active against HSV. In addition, we also analysed the content of the alkaloid fraction of the plant by capillary gas chromatography-mass spectrometry (GC-MS) and identified lycopodine as the major alkaloid (60.8%).

  2. Determining the absolute abundance of dinoflagellate cysts in recent marine sediments: The Lycopodium marker-grain method put to the test

    DEFF Research Database (Denmark)

    Mertens, K; Verhoeven; Verleye

    2009-01-01

    Absolute abundances (concentrations) of dinoflagellate cysts are often determined through the addition of Lycopodium clavatum marker-grains as a spike to a sample before palynological processing. An inter-laboratory calibration exercise was set up in order to test the comparability of results obt...

  3. Tom Ford Construction, LLC Information Sheet

    Science.gov (United States)

    Tom Ford Construction, LLC (the Company) is located in Brentwood, Tennessee. The settlement involves renovation activities conducted at a property constructed prior to 1978, located in Nashville, Tennessee.

  4. 石松生物碱化学成分的研究%Study on chemical constituents of Lycopodium alkaloids

    Institute of Scientific and Technical Information of China (English)

    刘慧杰; 汪冶

    2012-01-01

    目的:研究石松Lycopodium japonicu生物碱化学成分.方法:采用硅胶柱色谱,RP-C18反相柱色谱,SephadexLH-20柱色谱,Waters半制备液相色谱等方法分离纯化,根据理化性质和波谱数据鉴定化合物的结构.结果:从石松中分离并鉴定了9个生物碱化学成分,分别为lycodoline(1),lucidioline(2),α-obscurine(3),lycopodine(4),lycoposerramine-L(5),lycoposerramine-M (6),11 α-O-acetyl-lycopodine (7),des-N-methyl-α-obscurine (8),clavolonine(9),其中化合物4~9为首次报道从石松中分离得到.%Objective; To study the alkaloid chemical constituents of Lycopodium japonicum. Method; Compounds were isolated and purified by such methods as silica gel column chromatography, RP-C18 reversed phase column chromatography, Sephadex LH-20 column chromatography and Waters semi-preparative liquid chromatogram, and their structures were identified based on physico-chemical property and spectrum data. Result; Nine known alkaloid chemical constituents were isolated and identified, they were ly-codoline(l) ,lucidioline(2) ,α-obscurine(3) ,lycopodine (4) ,lycoposerramine-L(5) ,lycoposerramine-M (6) , 11α-O-acetyl-lycopod-ine (7) , des-N-methyl-a-obscurine (8) , clavolonine (9). Conclusion; Compounds 4-9 were obtained from L. Japonicum for the first time.

  5. Updating the Micro-Tom TILLING platform.

    Science.gov (United States)

    Okabe, Yoshihiro; Ariizumi, Tohru; Ezura, Hiroshi

    2013-03-01

    The dwarf tomato variety Micro-Tom is regarded as a model system for functional genomics studies in tomato. Various tomato genomic tools in the genetic background of Micro-Tom have been established, such as mutant collections, genome information and a metabolomic database. Recent advances in tomato genome sequencing have brought about a significant need for reverse genetics tools that are accessible to the larger community, because a great number of gene sequences have become available from public databases. To meet the requests from the tomato research community, we have developed the Micro-Tom Targeting-Induced Local Lesions IN Genomes (TILLING) platform, which is comprised of more than 5000 EMS-mutagenized lines. The platform serves as a reverse genetics tool for efficiently identifying mutant alleles in parallel with the development of Micro-Tom mutant collections. The combination of Micro-Tom mutant libraries and the TILLING approach enables researchers to accelerate the isolation of desirable mutants for unraveling gene function or breeding. To upgrade the genomic tool of Micro-Tom, the development of a new mutagenized population is underway. In this paper, the current status of the Micro-Tom TILLING platform and its future prospects are described.

  6. Tomás Carrasquilla

    Directory of Open Access Journals (Sweden)

    Amalia Franco Castaño

    2014-01-01

    Full Text Available El reconocimiento de la obra del escritor antioqueño Tomás Carrasquilla, como una obra asociada al realismo y a los principios de interpretación de las relaciones sociales que esta propuesta implica permite que, desde la composición, el esquema de los personajes y los usos del lenguaje, pueda leerse una postura crítica que se distan - cia de las normas estéticas vigentes, para mostrar las contradicciones y los desacuerdos con los proyectos políticos e ideológicos que las respaldaban. Es así como Carrasquilla concreta en una novela como La Marquesa de Yolombó la expresión de una toma de posición que se respalda en la composición de un personaje femenino desde el cual expone no solo las implicaciones de una época de la sociedad colombiana sino, además, las posibilidades de comunicación con un presente que para el escritor amerita ser cuestionado y revelado desde la descomposición de la vida social y las contradicciones de los proyectos de liberación en Colombia.

  7. Inhibition of TMV multiplication by siRNA constructs against TOM1 and TOM3 genes of Capsicum annuum.

    Science.gov (United States)

    Kumar, Sunil; Dubey, Ashvini Kumar; Karmakar, Ruma; Kini, Kukkundoor Ramachandra; Mathew, Mathew Kuriyan; Prakash, Harischandra Sripathy

    2012-12-01

    The host proteins TOM1 and TOM3 associated with tonoplast membrane are shown to be required for efficient multiplication of Tobamoviruses. In this study, homologous of TOM1 and TOM3 genes were identified in pepper (Capsicum annuum) using specific primers. Their gene sequences have similarity to Nicotiana tabacum NtTOM1 and NtTOM3. Sequence alignment showed that CaTOM1 and CaTOM3 are closely related to TOM1 and TOM3 of N. tabacum and Solanum lycopersicum with 90% and 70% nucleotide sequence identities, respectively. RNA interference approach was used to suppress the TOM1 and TOM3 gene expression which in turn prevented Tobacco mosaic virus replication in tobacco. Nicotiana plants agro-infiltrated with siRNA constructs of TOM1 or TOM3 showed no mosaic or necrotic infection symptoms upon inoculation with TMV. The results indicated that silencing of TOM1 and TOM3 of pepper using the siRNA constructs is an efficient method for generating TMV-resistant plants. Crown Copyright © 2012. Published by Elsevier B.V. All rights reserved.

  8. Structural analysis of a sulfated polysaccharidic fraction obtained from the coenocytic green seaweed Caulerpa cupressoides var. lycopodium

    Directory of Open Access Journals (Sweden)

    José Ariévilo Gurgel Rodrigues

    2014-04-01

    Full Text Available Researches on structural chemistry of sulfated polysaccharides (SPs have been mainly focused on red and brown algae. Caulerpa cupressoides var. lycopodium (Chlorophyta contains three SPs fractions (Cc-SP1, Cc-SP2 and Cc-SP3. Cc-SP1 and Cc-SP2 had anticoagulant (in vitro and anti- and prothrombotic, antinociceptive and/or anti-inflammatory (in vivo effects. However, their structural features have not yet been investigated. This study analyzed the chemical composition, elemental microanalysis and structural features by infrared (IR and nuclear magnetic resonance (1H NMR spectroscopy of Cc-SPs. Fractionation of SPs by DEAE-cellulose yielded Cc-SP1, Cc-SP2 and CcSP3 containing differences among the relative proportions of sulfate (14.67-26.72%, total sugars (34.92-49.73% and uronic acid (7.15-7.22%. Carbon (21.76-29.62%, sulfate (2.16-4.55%, nitrogen (0.85-1.57% and hydrogen (4.57-5.86% contents were obtained using a CHN equipment. Data from IR indicated occurrence of sulfate ester, galactose-6-sulfate, uronic acid and glycoside linkages. For 1H NMR spectrum of the soluble Cc-SP1 fraction, it was mainly found β-galactopyranose residues and CH3 group. The results showed that Cc-SPs fractions have some structural features similar to others studied Caulerpaceae SPs.

  9. LILBID-mass spectrometry of the mitochondrial preprotein translocase TOM.

    Science.gov (United States)

    Mager, Frauke; Sokolova, Lucie; Lintzel, Julia; Brutschy, Bernhard; Nussberger, Stephan

    2010-11-17

    In the present work we applied a novel mass spectrometry method termed laser-induced liquid bead ion desorption mass spectrometry (LILBID-MS) to the outer mitochondrial membrane protein translocon TOM to analyze its subunit composition and stoichiometry. With TOM core complex, purified at high pH, we demonstrate that a TOM core complex of Neurospora crassa is composed of at least two Tom40 and Tom22 molecules, respectively, and more than five small Tom subunits between 5.5 and 6.4 kDa. We show that the multiprotein complex has a total molecular mass higher than 170 depending on the number of Tom5, Tom6 and Tom7 molecules bound.

  10. Comparison of 454-ESTs from Huperzia serrata and Phlegmariurus carinatus reveals putative genes involved in lycopodium alkaloid biosynthesis and developmental regulation

    Directory of Open Access Journals (Sweden)

    Steinmetz André

    2010-09-01

    Full Text Available Abstract Background Plants of the Huperziaceae family, which comprise the two genera Huperzia and Phlegmariurus, produce various types of lycopodium alkaloids that are used to treat a number of human ailments, such as contusions, swellings and strains. Huperzine A, which belongs to the lycodine type of lycopodium alkaloids, has been used as an anti-Alzheimer's disease drug candidate. Despite their medical importance, little genomic or transcriptomic data are available for the members of this family. We used massive parallel pyrosequencing on the Roche 454-GS FLX Titanium platform to generate a substantial EST dataset for Huperzia serrata (H. serrata and Phlegmariurus carinatus (P. carinatus as representative members of the Huperzia and Phlegmariurus genera, respectively. H. serrata and P. carinatus are important plants for research on the biosynthesis of lycopodium alkaloids. We focused on gene discovery in the areas of bioactive compound biosynthesis and transcriptional regulation as well as genetic marker detection in these species. Results For H. serrata, 36,763 unique putative transcripts were generated from 140,930 reads totaling over 57,028,559 base pairs; for P. carinatus, 31,812 unique putative transcripts were generated from 79,920 reads totaling over 30,498,684 base pairs. Using BLASTX searches of public databases, 16,274 (44.3% unique putative transcripts from H. serrata and 14,070 (44.2% from P. carinatus were assigned to at least one protein. Gene Ontology (GO and Kyoto Encyclopedia of Genes and Genomes (KEGG orthology annotations revealed that the functions of the unique putative transcripts from these two species cover a similarly broad set of molecular functions, biological processes and biochemical pathways. In particular, a total of 20 H. serrata candidate cytochrome P450 genes, which are more abundant in leaves than in roots and might be involved in lycopodium alkaloid biosynthesis, were found based on the comparison of H

  11. Tom Olaf Urb / intervjueerinud Siim Õ. Ilves

    Index Scriptorium Estoniae

    Urb, Tom Olaf, 1985-

    2016-01-01

    Muusik, produtsent, kirjanik ja näitleja Tom-Olaf Urb, lavanimega Reket, arutleb disaini teemal ja nimetab kümme disainieset, mis teda elus köitnud on. Eesti Hip-Hop auhindade jagamisel valiti Reketi "Tuule tee" 2015.a. parimaks kodumaiseks hip-hop albumiks

  12. Tom Sawyer,an Imitated Autobiographical Book

    Institute of Scientific and Technical Information of China (English)

    唐廷君

    2009-01-01

    Mark Twain's masterpiece children novel The Adventures of Tom Sawyer is critically agreed autobiographical novel.The author has left behind a wealth of autobiographical materials supposing it.But the novel is not an original one.The author also has also borrowed many from other writers.So it is considered an imitated autobiographical book.

  13. Tom Wolfe and the Uses of Argument.

    Science.gov (United States)

    Kallan, Richard A.

    Tom Wolfe is widely regarded as the leading theorist and practitioner of New Journalism, the journalistic genre that combines the stylistic features of fiction and the reportorial obligations of journalism to produce a "novelistic sounding" but nonetheless factual literature. The saliency of Wolfe's stylistic boldness has prompted many…

  14. Tom Olaf Urb / intervjueerinud Siim Õ. Ilves

    Index Scriptorium Estoniae

    Urb, Tom Olaf, 1985-

    2016-01-01

    Muusik, produtsent, kirjanik ja näitleja Tom-Olaf Urb, lavanimega Reket, arutleb disaini teemal ja nimetab kümme disainieset, mis teda elus köitnud on. Eesti Hip-Hop auhindade jagamisel valiti Reketi "Tuule tee" 2015.a. parimaks kodumaiseks hip-hop albumiks

  15. STS-98 Crew Interview: Tom Jones

    Science.gov (United States)

    2001-01-01

    The STS-98 Mission Specialist Tom Jones is seen being interviewed. He answers questions about his inspiration to become an astronaut, his career path, and his training. He gives details on the mission's goals and significance, and the payload and hardware it brings to the International Space Station (ISS). Mr. Jones discusses his role in the mission's spacewalks and activities.

  16. Social versus Intrapersonal ToM: Social ToM Is a Cognitive Strength for Low- and Middle-SES Children

    Science.gov (United States)

    Lucariello, Joan M.; Durand, Tina M.; Yarnell, Lisa

    2007-01-01

    Metarepresentational theory of mind (ToM) was studied in middle- and low-SES five- and six-year-olds. Two aspects of ToM were distinguished. Reasoning about one's own mental states (Intrapersonal ToM) was assessed in the intrapersonal ToM task condition and reasoning about others' mental states (Social ToM) was assessed in the social ToM task…

  17. Role of phosphate solubilizing Burkholderia spp. for successful colonization and growth promotion of Lycopodium cernuum L. (Lycopodiaceae) in lateritic belt of Birbhum district of West Bengal, India.

    Science.gov (United States)

    Ghosh, Ranjan; Barman, Soma; Mukherjee, Rajib; Mandal, Narayan C

    2016-02-01

    Profuse growth of Lycpodium cernuum L. was found in phosphate deficient red lateritic soil of West Bengal, India. Interaction of vesicular-arbuscular mycorrhiza (VAM) with Lycopodium rhizoids were described earlier but association of PGPR with their rhizoids were not studied. Three potent phosphate solubilizing bacterial strains (P4, P9 and P10) associated with L. cernuum rhizoids were isolated and identified by 16S rDNA homologies on Ez-Taxon database as Burkholderia tropica, Burkholderia unamae and Burkholderia cepacia respectively. Day wise kinetics of phosphate solubilization against Ca3(PO4)2 suggested P4 (580.56±13.38 μg ml(-1)) as maximum mineral phosphate solubilizer followed by P9 (517.12±17.15 μg ml(-1)) and P10 (485.18±14.23 μg ml(-1)) at 28 °C. Release of bound phosphates by isolated strains from ferric phosphate (FePO4), aluminum phosphate (AlPO4) and four different complex rock phosphates indicated their very good phosphate solubilizng efficacy. Nitrogen independent solubilizition also supports their nitrogen fixing capabilities. Inhibition of P solubilization by calcium salts and induction by EDTA suggested pH dependent chelation of metal cations by all of the isolates. Rhizoidal colonization potentials of Burkholderia spp. were confirmed by in planta experiment and also using scanning electron microscope (SEM). Increases of total phosphate content in Lycopodium plants upon soil treatment with these isolates were also recorded. In addition siderophore production on CAS agar medium, tryptophan dependent IAA production and antifungal activities against pathogenic fungi by rhizospheric isolates deep-rooted that they have definite role in nutrient mobilization for successful colonization of L. cernuum in nutrient deficient lateritic soil.

  18. Tropical easterly jet located using TOMS data

    Science.gov (United States)

    Bolhofer, William C.

    1987-01-01

    The formative stages of the onset of the 1979 southwest monsoon was marked by a WNW-ESE oriented band of marine convection over the South Arabian Sea. This convection was first observed on June 10, 1979 using satellite cloud imagery. The marine convection appeared during a major acceleration of the upper troposphere easterly wind field. A composite vertical meridional cross-section of upper level winds for June 11, revealed the core of the Tropical Easterly Jet (TEJ) at 115 mb, 9.5 deg N. Time analysis of the upper level wind field over the Tropical Wind Observing Ship (TWOS) polygon show a lowering of both the pressure level of maximum wind and tropopause level with acceleration of the upper level easterlies. The tropopause was as much as 20 mb lower on the equatorial side of the TEJ. Streamline analysis of the maximum observed easterly winds over India did not reveal the horizontal position of the TEJ. Careful analysis of Total Ozone Mapping Spectrometer (TOMS) data for June 11, 1979 showed relatively high values of ozone south of India. It was observed that the latitudinal position of the TEJ on June 11, at approximately 70 deg E coincided with the northern edge of relatively high ozone values. Using this as a reference, the TEJ core was identified as far as NE Bay of Bengal (the limits of the available TOMS data).

  19. 78 FR 12307 - Taylor, G. Tom; Notice of Filing

    Science.gov (United States)

    2013-02-22

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF ENERGY Federal Energy Regulatory Commission Taylor, G. Tom; Notice of Filing Take notice that on February 14, 2013, G. Tom Taylor filed an application to hold interlocking positions pursuant to section 305(b) of the...

  20. TOM9.2 Is a Calmodulin-Binding Protein Critical for TOM Complex Assembly but Not for Mitochondrial Protein Import in Arabidopsis thaliana.

    Science.gov (United States)

    Parvin, Nargis; Carrie, Chris; Pabst, Isabelle; Läßer, Antonia; Laha, Debabrata; Paul, Melanie V; Geigenberger, Peter; Heermann, Ralf; Jung, Kirsten; Vothknecht, Ute C; Chigri, Fatima

    2017-04-03

    The translocon on the outer membrane of mitochondria (TOM) facilitates the import of nuclear-encoded proteins. The principal machinery of mitochondrial protein transport seems conserved in eukaryotes; however, divergence in the composition and structure of TOM components has been observed between mammals, yeast, and plants. TOM9, the plant homolog of yeast Tom22, is significantly smaller due to a truncation in the cytosolic receptor domain, and its precise function is not understood. Here we provide evidence showing that TOM9.2 from Arabidopsis thaliana is involved in the formation of mature TOM complex, most likely by influencing the assembly of the pore-forming subunit TOM40. Dexamethasone-induced RNAi gene silencing of TOM9.2 results in a severe reduction in the mature TOM complex, and the assembly of newly imported TOM40 into the complex is impaired. Nevertheless, mutant plants are fully viable and no obvious downstream effects of the loss of TOM complex, i.e., on mitochondrial import capacity, were observed. Furthermore, we found that TOM9.2 can bind calmodulin (CaM) in vitro and that CaM impairs the assembly of TOM complex in the isolated wild-type mitochondria, suggesting a regulatory role of TOM9.2 and a possible integration of TOM assembly into the cellular calcium signaling network. Copyright © 2017 The Author. Published by Elsevier Inc. All rights reserved.

  1. A review of the Tom Rozwadowski medal

    Directory of Open Access Journals (Sweden)

    HW Ittmann

    2013-06-01

    Full Text Available The Tom Rozwadowski (TR medal is the most prestigious award of the Operations Research Society of South Africa (ORSSA. The award, first presented in 1971, was established in honour of one of ORSSA's founding members. Initially the medal was to be presented to a member of the society for a paper of most outstanding merit, but the rules were subsequently adapted and currently the medal is awarded to the best paper published during the previous calendar year. This review endeavours to present an analysis of all the award winning papers since its inception. The aim is three-fold, namely: to present a historical review, to detect any trends within Operations Research (OR in South Africa and to present a view of OR in the country. The analysis indicates that these award-winning papers are very diverse in nature, which certainly epitomises OR in South Africa, but the sample is small and thus not representative enough to be used to draw strict conclusions about the evolution of OR in South Africa. The papers, in general, exhibit originality, quality and clarity of exposition while there is clear interaction between theory and practice.

  2. Tom Russell: "Õpetajakoolitust tuleks alustada praktikast" / Liisa Lumiste

    Index Scriptorium Estoniae

    Lumiste, Liisa

    2013-01-01

    Eduko programmi raames Tallinna Ülikoolis toimunud avalikul loengul rääkis Kanada kasvatusteadlane Tom Russell praktika tähtsusest õpetajakoolituses ja viis läbi meistriklassi õpetajakoolituse õppejõududele

  3. Tom Russell: "Õpetajakoolitust tuleks alustada praktikast" / Liisa Lumiste

    Index Scriptorium Estoniae

    Lumiste, Liisa

    2013-01-01

    Eduko programmi raames Tallinna Ülikoolis toimunud avalikul loengul rääkis Kanada kasvatusteadlane Tom Russell praktika tähtsusest õpetajakoolituses ja viis läbi meistriklassi õpetajakoolituse õppejõududele

  4. Symmetry and fundamental physics : Tom Kibble at 80

    CERN Document Server

    2014-01-01

    Tom Kibble is an inspirational theoretical physicist who has made profound contributions to our understanding of the physical world. To celebrate his 80th birthday a one-day symposium was held on March 13, 2013 at the Blackett Laboratory, Imperial College, London. This important volume is a compilation of papers based on the presentations that were given at the symposium. The symposium profiled various aspects of Tom's long scientific career. The tenor of the meeting was set in the first talk given by Neil Turok, director of the Perimeter Institute for Theoretical Physics, who described Tom as our guru and example . He gave a modern overview of cosmological theories, including a discussion of Tom's pioneering work on how topological defects might have formed in the early universe during symmetry-breaking phase transitions. Wojciech Zurek of Los Alamos National Laboratory continued with this theme, surveying analogous processes within the context of condensed matter systems and explaining the Kibble Zurek sc...

  5. Cryo-EM Structure of the TOM Core Complex from Neurospora crassa.

    Science.gov (United States)

    Bausewein, Thomas; Mills, Deryck J; Langer, Julian D; Nitschke, Beate; Nussberger, Stephan; Kühlbrandt, Werner

    2017-08-10

    The TOM complex is the main entry gate for protein precursors from the cytosol into mitochondria. We have determined the structure of the TOM core complex by cryoelectron microscopy (cryo-EM). The complex is a 148 kDa symmetrical dimer of ten membrane protein subunits that create a shallow funnel on the cytoplasmic membrane surface. In the core of the dimer, the β-barrels of the Tom40 pore form two identical preprotein conduits. Each Tom40 pore is surrounded by the transmembrane segments of the α-helical subunits Tom5, Tom6, and Tom7. Tom22, the central preprotein receptor, connects the two Tom40 pores at the dimer interface. Our structure offers detailed insights into the molecular architecture of the mitochondrial preprotein import machinery. Copyright © 2017 Elsevier Inc. All rights reserved.

  6. Tomato的来历:Tom ate those

    Institute of Scientific and Technical Information of China (English)

    2005-01-01

    你听说过有关西红柿(tomato)来历的小故事吗?从前有个叫汤姆的小男孩,吃了一只西红柿(当时还没有tomato这个词)。当时人们认为西红柿是有毒的,吃了就会死,于是其他的小朋友们惊恐地跑去通知汤姆的父母:“大事不好啦,汤姆吃了一个西红柿!”当然,他们是用英语说的:”Tom ate those,Tom ate those,Tom ate those!”据说这句话的发音和tomatos非常相似,因此成了tomato一词的起源。

  7. Shallow ground-water conditions, Tom Green County, Texas

    Science.gov (United States)

    Lee, J.N.

    1986-01-01

    Most of the water needs of Tom Green County, Texas, are supplied by ground water; however, the city of San Angelo is supplied by surface water. Groundwater withdrawals during 1980 (latest year for which data are available) in Tom Green County totaled about 15,300 acre-feet, all derived from shallow aquifers. Shallow aquifers in this report refer to the ground-water system generally less than 400 feet deep that contains water with less than a 10,000 milligrams per liter concentration of dissolved solids; aquifers comprising this system include: The Leona, Comanche Peak, Trinity, Blaine, San Angelo, Choza, Bullwagon, Vale, Standpipe, and Arroyo aquifers.

  8. Tomás Navarro Tomás and the origins of experimental phonetics at the JAE

    Directory of Open Access Journals (Sweden)

    Sánchez Ron, José M.

    2007-12-01

    Full Text Available The introduction in Spain of experimental phonetics, a branch of linguistic close to science, had as one of its main protagonists Tomás Navarro Tomás, who was the director of a Laboratory of Phonetics at the Historical Studies Center of the Junta para Ampliación de Estudios. In this article, we study Navarro Tomás’s education in that field, making use of the letters he sent to Ramón Menéndez Pidal while he was abroad (France and Germany supported by the Junta in 1912-1913. Besides, that correspondence presents an splendid view of the European phonetic community of the time.

    La introducción en España de la fonética experimental, una rama de la lingüística fronteriza con las ciencias, tuvo como uno de sus principales protagonistas a Tomás Navarro Tomás, que dirigió un Laboratorio de Fonética en el Centro de Estudios Históricos de la Junta para Ampliación de Estudios. En este artículo se reconstruye una parte esencial de la formación de Navarro Tomás en ese campo, utilizando para ello las cartas que envió a Ramón Menéndez Pidal mientras estuvo pensionado en el extranjero (Francia y Alemania por la Junta en 1912-1913. Se trata de una correspondencia que, además, presenta una excelente visión de la comunidad fonética europea de la época.

  9. New Whole-House Solutions Case Study: Tom Walsh & Co.

    Energy Technology Data Exchange (ETDEWEB)

    none,

    2013-02-01

    Tom Walsh & Company’s homes in an urban infill project in Portland achieved meets 2012 IECC insulation requirements in the marine climate with R-21 fiberglass batt walls, R-25 slab insulation and R-49 spray foam and cellulose attic floors.

  10. Isepäine iseõppija Tom Dixon

    Index Scriptorium Estoniae

    2007-01-01

    Inglise disainerist Tom Dixonist (sünd. 1959) ja tema loomingust. 1998. aastast UK disainistuudio juht mööblifirma Habitat juures, mööblitööstuse Artek loominguline direktor. Aprillis 2007 esines Milano mööblimessil vaskvalgustite kollektsiooniga ja Triennale pargis koostöös Shigeru Baniga Arteki paviljoniga

  11. Isepäine iseõppija Tom Dixon

    Index Scriptorium Estoniae

    2007-01-01

    Inglise disainerist Tom Dixonist (sünd. 1959) ja tema loomingust. 1998. aastast UK disainistuudio juht mööblifirma Habitat juures, mööblitööstuse Artek loominguline direktor. Aprillis 2007 esines Milano mööblimessil vaskvalgustite kollektsiooniga ja Triennale pargis koostöös Shigeru Baniga Arteki paviljoniga

  12. Culture of the Tomato Micro-Tom Cultivar in Greenhouse.

    Science.gov (United States)

    Rothan, Christophe; Just, Daniel; Fernandez, Lucie; Atienza, Isabelle; Ballias, Patricia; Lemaire-Chamley, Martine

    2016-01-01

    Micro-Tom tomato cultivar is particularly adapted to the development of genomic approaches in tomato. Here, we describe the culture of this plant in greenhouse, including climate regulation, seed sowing and watering, vegetative development, plant maintenance, including treatment of phytosanitary problems, and reproductive development.

  13. TOMS Data Products at the NASA Goddard Earth Sciences DAAC

    Science.gov (United States)

    Ahmad, S. P.; Johnson, J. E.; Serafino, G. N.; McPeters, R. D.

    2002-05-01

    The current Total Mapping Ozone Spectrometer (TOMS) was launched aboard the NASA Earth Probe (EP) satellite in July1996 to provide global monitoring of total column atmospheric ozone derived from measurements of backscattered solar ultraviolet radiation. TOMS is a second-generation, ozone-sounding instrument based on the Backscatter Ultraviolet (BUV) Spectrometer flown aboard NASA's Nimbus-4 satellite in 1970. The first TOMS instrument was launched aboard Nimbus-7 in 1978. Nimbus-7 TOMS provided data continuously for more than 14 years until May 1993. From 1991 through 1994, a second TOMS instrument was also flown aboard a Russian Meteor-3 satellite, and the third instrument in the series is the currently operating EP-TOMS. A fourth instrument was flown on the Japanese Advanced Environmental Orbiting Satellite (ADEOS) in August 1996 but prematurely ended 9 months later. The high quality measurements of TOMS played an instrumental role in the detection of a small but steady ozone decline since the early 1980s. In September 1991, the Upper Atmosphere Research Satellite (UARS) was launched containing a comprehensive suite of instruments designed to collectively determine the impact of chemical, dynamic and energy input processes on ozone creation and destruction. In addition to its primary role of ozone monitoring, TOMS has also provided (1) estimates of harmful UV-B radiation at the surface, (2) the effective UV reflectivity due to the combined effects of clouds, aerosols, and the earth's surface, (3) an index to track the global transport of ash and sulfur dioxide resulting from volcanic eruptions, and (4) an index to track smoke emanating from large fires and dust plumes originating from desert regions. Aerosol characteristics including optical depth and single scattering albedo are also being produced as evaluation products at this time. Continuity of ozone, other trace species, and solar UV measurements will be provided with the launch of the Aura spacecraft in

  14. TOMS/EP UV Aerosol Index Daily and Monthly Zonal Means V008

    Data.gov (United States)

    National Aeronautics and Space Administration — This data product contains TOMS/EP UV Aerosol Index Daily and Monthly Zonal Means Version 8 data in ASCII format. (The shortname for this Level-3 Earth Probe TOMS...

  15. Measuring Theory of Mind in Children. Psychometric Properties of the ToM Storybooks

    NARCIS (Netherlands)

    Blijd-Hoogewys, E. M. A.; van Geert, P. L. C.; Serra, M.; Minderaa, R. B.

    2008-01-01

    Although research on Theory-of-Mind (ToM) is often based on single task measurements, more comprehensive instruments result in a better understanding of ToM development. The ToM Storybooks is a new instrument measuring basic ToM-functioning and associated aspects. There are 34 tasks, tapping various

  16. Measuring Theory of Mind in Children. Psychometric Properties of the ToM Storybooks

    NARCIS (Netherlands)

    Blijd-Hoogewys, E. M. A.; van Geert, P. L. C.; Serra, M.; Minderaa, R. B.

    2008-01-01

    Although research on Theory-of-Mind (ToM) is often based on single task measurements, more comprehensive instruments result in a better understanding of ToM development. The ToM Storybooks is a new instrument measuring basic ToM-functioning and associated aspects. There are 34 tasks, tapping various

  17. 77 FR 39406 - Safety Zone; Tom Graves Memorial Fireworks, Port Bay, Wolcott, NY

    Science.gov (United States)

    2012-07-03

    ... SECURITY Coast Guard 33 CFR Part 165 RIN 1625-AA00 Safety Zone; Tom Graves Memorial Fireworks, Port Bay... from a portion of Port Bay during the Tom Graves Memorial Fireworks display. This temporary safety zone... vessels during the Tom Graves Memorial Fireworks. This zone will be effective and enforced from 9:30 p.m...

  18. Alternative function for the mitochondrial SAM complex in biogenesis of alpha-helical TOM proteins.

    Science.gov (United States)

    Stojanovski, Diana; Guiard, Bernard; Kozjak-Pavlovic, Vera; Pfanner, Nikolaus; Meisinger, Chris

    2007-12-03

    The mitochondrial outer membrane contains two preprotein translocases: the general translocase of outer membrane (TOM) and the beta-barrel-specific sorting and assembly machinery (SAM). TOM functions as the central entry gate for nuclear-encoded proteins. The channel-forming Tom40 is a beta-barrel protein, whereas all Tom receptors and small Tom proteins are membrane anchored by a transmembrane alpha-helical segment in their N- or C-terminal portion. Synthesis of Tom precursors takes place in the cytosol, and their import occurs via preexisting TOM complexes. The precursor of Tom40 is then transferred to SAM for membrane insertion and assembly. Unexpectedly, we find that the biogenesis of alpha-helical Tom proteins with a membrane anchor in the C-terminal portion is SAM dependent. Each SAM protein is necessary for efficient membrane integration of the receptor Tom22, whereas assembly of the small Tom proteins depends on Sam37. Thus, the substrate specificity of SAM is not restricted to beta-barrel proteins but also includes the majority of alpha-helical Tom proteins.

  19. Biogenesis of the mitochondrial TOM complex: Mim1 promotes insertion and assembly of signal-anchored receptors.

    Science.gov (United States)

    Becker, Thomas; Pfannschmidt, Sylvia; Guiard, Bernard; Stojanovski, Diana; Milenkovic, Dusanka; Kutik, Stephan; Pfanner, Nikolaus; Meisinger, Chris; Wiedemann, Nils

    2008-01-04

    The translocase of the outer membrane (TOM complex) is the central entry gate for nuclear-encoded mitochondrial precursor proteins. All Tom proteins are also encoded by nuclear genes and synthesized as precursors in the cytosol. The channel-forming beta-barrel protein Tom40 is targeted to mitochondria via Tom receptors and inserted into the outer membrane by the sorting and assembly machinery (SAM complex). A further outer membrane protein, Mim1, plays a less defined role in assembly of Tom40 into the TOM complex. The three receptors Tom20, Tom22, and Tom70 are anchored in the outer membrane by a single transmembrane alpha-helix, located at the N terminus in the case of Tom20 and Tom70 (signal-anchored) or in the C-terminal portion in the case of Tom22 (tail-anchored). Insertion of the precursor of Tom22 into the outer membrane requires pre-existing Tom receptors while the import pathway of the precursors of Tom20 and Tom70 is only poorly understood. We report that Mim1 is required for efficient membrane insertion and assembly of Tom20 and Tom70, but not Tom22. We show that Mim1 associates with SAM(core) components to a large SAM complex, explaining its role in late steps of the assembly pathway of Tom40. We conclude that Mim1 is not only required for biogenesis of the beta-barrel protein Tom40 but also for membrane insertion and assembly of signal-anchored Tom receptors. Thus, Mim1 plays an important role in the efficient assembly of the mitochondrial TOM complex.

  20. TOM software toolbox: acquisition and analysis for electron tomography.

    Science.gov (United States)

    Nickell, Stephan; Förster, Friedrich; Linaroudis, Alexandros; Net, William Del; Beck, Florian; Hegerl, Reiner; Baumeister, Wolfgang; Plitzko, Jürgen M

    2005-03-01

    Automated data acquisition procedures have changed the perspectives of electron tomography (ET) in a profound manner. Elaborate data acquisition schemes with autotuning functions minimize exposure of the specimen to the electron beam and sophisticated image analysis routines retrieve a maximum of information from noisy data sets. "TOM software toolbox" integrates established algorithms and new concepts tailored to the special needs of low dose ET. It provides a user-friendly unified platform for all processing steps: acquisition, alignment, reconstruction, and analysis. Designed as a collection of computational procedures it is a complete software solution within a highly flexible framework. TOM represents a new way of working with the electron microscope and can serve as the basis for future high-throughput applications.

  1. Highlights of TOMS Version 9 Total Ozone Algorithm

    Science.gov (United States)

    Bhartia, Pawan; Haffner, David

    2012-01-01

    The fundamental basis of TOMS total ozone algorithm was developed some 45 years ago by Dave and Mateer. It was designed to estimate total ozone from satellite measurements of the backscattered UV radiances at few discrete wavelengths in the Huggins ozone absorption band (310-340 nm). Over the years, as the need for higher accuracy in measuring total ozone from space has increased, several improvements to the basic algorithms have been made. They include: better correction for the effects of aerosols and clouds, an improved method to account for the variation in shape of ozone profiles with season, latitude, and total ozone, and a multi-wavelength correction for remaining profile shape errors. These improvements have made it possible to retrieve total ozone with just 3 spectral channels of moderate spectral resolution (approx. 1 nm) with accuracy comparable to state-of-the-art spectral fitting algorithms like DOAS that require high spectral resolution measurements at large number of wavelengths. One of the deficiencies of the TOMS algorithm has been that it doesn't provide an error estimate. This is a particular problem in high latitudes when the profile shape errors become significant and vary with latitude, season, total ozone, and instrument viewing geometry. The primary objective of the TOMS V9 algorithm is to account for these effects in estimating the error bars. This is done by a straightforward implementation of the Rodgers optimum estimation method using a priori ozone profiles and their error covariances matrices constructed using Aura MLS and ozonesonde data. The algorithm produces a vertical ozone profile that contains 1-2.5 pieces of information (degrees of freedom of signal) depending upon solar zenith angle (SZA). The profile is integrated to obtain the total column. We provide information that shows the altitude range in which the profile is best determined by the measurements. One can use this information in data assimilation and analysis. A side

  2. CSR Driven Brand Marketing: The Case of Toms

    OpenAIRE

    Mensah, Doris

    2016-01-01

    This research investigates the concept of Corporate Social Responsibility and Branding and how organizations can integrate CSR initiatives with strategic brand management. The project analyzed and discussed Toms Group CSR activities in West Africa more especially in Ghana in relation to child labor and the conditions of cocoa farmers and what the company is doing in terms of CSR strategy that can benefit the brand of the company. The study empirically made semi-structured interviews with t...

  3. Tom Bissel, Voglia di vincere/Extra Lives

    Directory of Open Access Journals (Sweden)

    Ambra Agnoletto

    2013-03-01

    Full Text Available Leggere il libro di Tom Bissell Extra lives: Why Video Games Matter, tradotto in Italia con il titolo Voglia di vincere, è stata un’impresa. L’impresa di qualcuno abituato a muoversi in ambito cinematografico e musicale, ma che affronta con l’entusiasmo e le incertezze del neofita i videogames e tutto ciò che riguarda la sfera videoludica, nei suoi aspetti creativi, estetici, di design e meccanica di gioco.

  4. El último neogranadino. Don Tomás Rueda Vargas

    Directory of Open Access Journals (Sweden)

    Eduardo Carranza

    1966-06-01

    Full Text Available Pronto se cumplirá un cuarto de siglo de la muerte de don Tomás Rueda Vargas. En un claro día de julio se nos fue el inolvidable maestro. La sabana era un idilio verde con sol. La dulce curva de los cerros, apenas violeta, apenas víspera de azul, se afinaba entre la neblina de nácar.

  5. Dorian Gray, Tom Ripley, and the Queer Closet

    OpenAIRE

    2003-01-01

    In their paper, "Dorian Gray, Tom Ripley, and the Queer Closet," Jonathan Alexander and Deborah Meem present and portray an imaginary conversation among an impossible but intriguing group of writers, critics, and fictional characters. These individuals speak in their own (published) voices, which are moderated by the author-facilitators and shaped into an extended rumination on art, the Doppelgänger, queerness, and literary influence. Through their dialogue, the actors reveal a tradition of t...

  6. Bruikbaarheid van snelheidsgegevens uit 'floating car data' voor proactieve verkeersveiligheidsanalyses : analyse van TomTom-snelheidsgegevens en vergelijking met meetlusgegevens op het provinciale wegennet.

    NARCIS (Netherlands)

    Aarts, L.T. Bijleveld, F.D. & Stipdonk, H.L.

    2015-01-01

    Usefulness of 'floating car speed data' for proactive road safety analyses : analysis of TomTom speed data and comparison with loop detector speed data of the provincial road network in the Netherlands. Currently, data on road crash casualties provide local authorities with insufficient starting

  7. Bruikbaarheid van snelheidsgegevens uit 'floating car data' voor proactieve verkeersveiligheidsanalyses : analyse van TomTom-snelheidsgegevens en vergelijking met meetlusgegevens op het provinciale wegennet.

    NARCIS (Netherlands)

    Aarts, L.T. Bijleveld, F.D. & Stipdonk, H.L.

    2015-01-01

    Usefulness of 'floating car speed data' for proactive road safety analyses : analysis of TomTom speed data and comparison with loop detector speed data of the provincial road network in the Netherlands. Currently, data on road crash casualties provide local authorities with insufficient starting poi

  8. Bruikbaarheid van snelheidsgegevens uit 'floating car data' voor proactieve verkeersveiligheidsanalyses : analyse van TomTom-snelheidsgegevens en vergelijking met meetlusgegevens op het provinciale wegennet.

    NARCIS (Netherlands)

    Aarts, L.T. Bijleveld, F.D. & Stipdonk, H.L.

    2015-01-01

    Usefulness of 'floating car speed data' for proactive road safety analyses : analysis of TomTom speed data and comparison with loop detector speed data of the provincial road network in the Netherlands. Currently, data on road crash casualties provide local authorities with insufficient starting poi

  9. 小麦TOM7蛋白类似基因的克隆与分析%Cloning and Characterization of TOM7-like Gene in Wheat

    Institute of Scientific and Technical Information of China (English)

    张政值; 马正强

    2005-01-01

    通过RT-PCR技术分离了编码小麦线粒体蛋白转运酶TOM7亚基(Translocase of Outer Mitochondrial Membrane subunit 7)的cDNA,并克隆了该基因编码区的基因组DNA,将该基因命名为TaTOM7.TaTOM7是一个没有内含子的基因,其编码的多肽具有一个位于中部的疏水跨膜区和两个分别位于N-端和C-端的亲水区域.来源于真菌、动物和植物的TOM7类似蛋白在疏水跨膜区高度保守,而在亲水区变异很大.在系统发育树中,TOM7类似蛋白可以按动物、植物和真菌分为3个类群.小麦TaTOM7在基因组中以寡拷贝形式存在,它的表达在Ms2近等基因系之间和不同组织之间存在差异.中国春缺体-四体及端二体系分析表明,TaTOM7位于小麦第3染色体同源群.%The cDNA encoding TOM7 (translocase of outer mitochondrial membrane subunit 7) like protein in wheat was cloned through RT-PCR,and its genomic DNA fragment was subsequently cloned. This gene was tentatively designated as TaTOM7. It has no intron in the coding region and its product possesses one hydrophobic trans-membrane domain in the middle,and one hydrophilic domain in the N-terminal and C-terminal domain, respectively. The amino acid composition in the trans-membrane domain of the TaTOM7 subunit is highly conserved among plants, animals and fungi. According to the phylogenetic tree,TOM7-like proteins from different species can be classified into three groups, representing plants,animals and fungi respectively. TaTOM7 is a single- or oligo-copy gene in the wheat genome,displaying different expression levels between Ms2 near-isogenic lines in some tissues,suggesting a role of Ms2 in its expression. TaTOM7 was mapped to chromosome group three of wheat.

  10. A comparison between Jubilee and Uncle Tom's Cabin

    Institute of Scientific and Technical Information of China (English)

    党兆颖; 谭惠娟

    2011-01-01

    @@ Jubilee was written by the black female novelist and poet Margaret Walker (1915-1998),which was characterized as a truthful record of the Black history and slavery around the Civil War.It refuted the biased images of the black people and challenged the dominant construction of history by reconstructing the history of black people from the aspect of black female.Its greatest value lies in its trutllful reflection of black people's life.While the great work of Uncle Tom's Cabin was slave novel written from the white female Writer's perspective.

  11. On the Study of Richard Tom Robert Identity

    CERN Document Server

    Tsai, Yeong-Shyeong

    2008-01-01

    In order to estimate the average speed of mosquitoes, a simple experiment was designed by Richard (Lu-Hsing Tsai), Tom (Po-Yu Tsai) and Robert (Hung-Ming Tsai). The result of the experiment was posted in the science exhibitions Taichung Taiwan 1993. The average speed of mosquitoes is inferred by the simple relation is obtained In this paper, we will show how to get the data generated by computer. Though the rigorous proof is not shown, a sketch proof will be shown in this paper

  12. Novel TPR-containing subunit of TOM complex functions as cytosolic receptor for Entamoeba mitosomal transport.

    Science.gov (United States)

    Makiuchi, Takashi; Mi-ichi, Fumika; Nakada-Tsukui, Kumiko; Nozaki, Tomoyoshi

    2013-01-01

    Under anaerobic environments, the mitochondria have undergone remarkable reduction and transformation into highly reduced structures, referred as mitochondrion-related organelles (MROs), which include mitosomes and hydrogenosomes. In agreement with the concept of reductive evolution, mitosomes of Entamoeba histolytica lack most of the components of the TOM (translocase of the outer mitochondrial membrane) complex, which is required for the targeting and membrane translocation of preproteins into the canonical aerobic mitochondria. Here we showed, in E. histolytica mitosomes, the presence of a 600-kDa TOM complex composed of Tom40, a conserved pore-forming subunit, and Tom60, a novel lineage-specific receptor protein. Tom60, containing multiple tetratricopeptide repeats, is localized to the mitosomal outer membrane and the cytosol, and serves as a receptor of both mitosomal matrix and membrane preproteins. Our data indicate that Entamoeba has invented a novel lineage-specific shuttle receptor of the TOM complex as a consequence of adaptation to an anaerobic environment.

  13. Meta-analysis of Theory of Mind (ToM) impairment in bipolar disorder.

    Science.gov (United States)

    Bora, E; Bartholomeusz, C; Pantelis, C

    2016-01-01

    Theory of mind (ToM) dysfunction is prominent in a number of psychiatric disorders, in particular, autism and schizophrenia, and can play a significant role in poor functioning. There is now emerging evidence suggesting that ToM abilities are also impaired in bipolar disorder (BP); however, the relationship between ToM deficits and mood state is not clear. We conducted a meta-analysis of ToM studies in BP. Thirty-four studies comparing 1214 patients with BP and 1097 healthy controls were included. BP groups included remitted (18 samples, 545 BP patients), subsyndromal (12 samples, 510 BP patients), and acute (manic and/or depressed) (10 samples, 159 BP patients) patients. ToM performance was significantly impaired in BP compared to controls. This impairment was evident across different types of ToM tasks (including affective/cognitive and verbal/visual) and was also evident in strictly euthymic patients with BP (d = 0.50). There were no significant differences between remitted and subsyndromal samples. However, ToM deficit was significantly more severe during acute episodes (d = 1.23). ToM impairment was significantly associated with neurocognitive and particularly with manic symptoms. Significant but modest sized ToM dysfunction is evident in remitted and subsyndromal BP. Acute episodes are associated with more robust ToM deficits. Exacerbation of ToM deficits may contribute to the more significant interpersonal problems observed in patients with acute or subsyndromal manic symptoms. There is a need for longitudinal studies comparing the developmental trajectory of ToM deficits across the course of the illness.

  14. Cognitive, Affective, and Conative Theory of Mind (ToM) in Children with Traumatic Brain Injury

    Science.gov (United States)

    Dennis, Maureen; Simic, Nevena; Bigler, Erin D.; Abildskov, Tracy; Agostino, Alba; Taylor, H. Gerry; Rubin, Kenneth; Vannatta, Kathryn; Gerhardt, Cynthia A.; Stancin, Terry; Yeates, Keith Owen

    2012-01-01

    We studied three forms of dyadic communication involving theory of mind (ToM) in 82 children with traumatic brain injury (TBI) and 61 children with orthopedic injury (OI): Cognitive (concerned with false belief), Affective (concerned with expressing socially deceptive facial expressions), and Conative (concerned with influencing another’s thoughts or feelings). We analyzed the pattern of brain lesions in the TBI group and conducted voxel-based morphometry for all participants in five large-scale functional brain networks, and related lesion and volumetric data to ToM outcomes. Children with TBI exhibited difficulty with Cognitive, Affective, and Conative ToM. The perturbation threshold for Cognitive ToM is higher than that for Affective and Conative ToM, in that Severe TBI disturbs Cognitive ToM but even Mild-Moderate TBI disrupt Affective and Conative ToM. Childhood TBI was associated with damage to all five large-scale brain networks. Lesions in the Mirror Neuron Empathy network predicted lower Conative ToM involving ironic criticism and empathic praise. Conative ToM was significantly and positively related to the package of Default Mode, Central Executive, and Mirror Neuron Empathy networks and, more specifically, to two hubs of the Default Mode network, the posterior cingulate/retrosplenial cortex and the hippocampal formation, including entorhinal cortex and parahippocampal cortex. PMID:23291312

  15. Tom Ten Have's contributions to causal inference and biostatistics: review and future research directions.

    Science.gov (United States)

    Small, Dylan S; Joffe, Marshall M; Lynch, Kevin G; Roy, Jason A; Russell Localio, A

    2014-09-10

    Tom Ten Have made many contributions to causal inference and biostatistics before his untimely death. This paper reviews Tom's contributions and discusses potential related future research directions. We focus on Tom's contributions to longitudinal/repeated measures categorical data analysis and particularly his contributions to causal inference. Tom's work on causal inference was primarily in the areas of estimating the effect of receiving treatment in randomized trials with nonadherence and mediation analysis. A related area to mediation analysis he was working on at the time of his death was posttreatment effect modification with applications to designing adaptive treatment strategies.

  16. Training older adults on Theory of Mind (ToM): transfer on metamemory.

    Science.gov (United States)

    Lecce, Serena; Bottiroli, Sara; Bianco, Federica; Rosi, Alessia; Cavallini, Elena

    2015-01-01

    Research on aging has shown a significant decline in ToM after 65 years of age. Despite these age-related difficulties, no study has yet investigated the possibility to improve ToM in older adults. To address this gap we tested the efficacy of a conversation-based ToM training with age-appropriate ToM tasks and its transfer effects on metamemory. We examined 72 older adults (Mage=67.61 years, SD=6.39 years) assigned to three training conditions: a ToM training, a physical-conversation training and a social-contact group. All participants took part in two 2-h testing and to two 2-h training sessions. Results showed that after the intervention, older adults in the ToM training group improved their mental states' understanding significantly more than participants in the physical-conversation training and in the social-contact groups. Crucially, the positive effect of the ToM intervention generalized to metamemory knowledge. This is the first study investigating the efficacy of a ToM training and its transfer effect on metacognition in older adults. From a theoretical point of view, it supports the relation between ToM and metamemory. Practical implications of these data are discussed. Copyright © 2014 Elsevier Ireland Ltd. All rights reserved.

  17. Cognitive, affective, and conative theory of mind (ToM) in children with traumatic brain injury.

    Science.gov (United States)

    Dennis, Maureen; Simic, Nevena; Bigler, Erin D; Abildskov, Tracy; Agostino, Alba; Taylor, H Gerry; Rubin, Kenneth; Vannatta, Kathryn; Gerhardt, Cynthia A; Stancin, Terry; Yeates, Keith Owen

    2013-07-01

    We studied three forms of dyadic communication involving theory of mind (ToM) in 82 children with traumatic brain injury (TBI) and 61 children with orthopedic injury (OI): Cognitive (concerned with false belief), Affective (concerned with expressing socially deceptive facial expressions), and Conative (concerned with influencing another's thoughts or feelings). We analyzed the pattern of brain lesions in the TBI group and conducted voxel-based morphometry for all participants in five large-scale functional brain networks, and related lesion and volumetric data to ToM outcomes. Children with TBI exhibited difficulty with Cognitive, Affective, and Conative ToM. The perturbation threshold for Cognitive ToM is higher than that for Affective and Conative ToM, in that Severe TBI disturbs Cognitive ToM but even Mild-Moderate TBI disrupt Affective and Conative ToM. Childhood TBI was associated with damage to all five large-scale brain networks. Lesions in the Mirror Neuron Empathy network predicted lower Conative ToM involving ironic criticism and empathic praise. Conative ToM was significantly and positively related to the package of Default Mode, Central Executive, and Mirror Neuron Empathy networks and, more specifically, to two hubs of the Default Mode Network, the posterior cingulate/retrosplenial cortex and the hippocampal formation, including entorhinal cortex and parahippocampal cortex. Copyright © 2012 Elsevier Ltd. All rights reserved.

  18. Voyeuristi alla finestra: Peeping Tom, dalla leggenda al cinema

    Directory of Open Access Journals (Sweden)

    Laura Staiano

    2015-01-01

    Full Text Available This essay deals with voyeuristic attitudes and ʹscopic powerʹ, i.e. the power to gaze at forbidden things and people without being seen. Indeed, its object par excellence coincides with female nakedness, while its subject is an invisible masculinity, which takes delight in looking.The paper is based on a study of the Anglo-Saxon legend of Lady Godiva and it is strictly connected with the subject of my dissertation in progress – metaphorical and physical blindness in 18th century French literature (since several voyeurs got blind because of their instincts and desires. Lady Godiva’s voyeur, called Peeping Tom, is struck blind for having looked out of his window and seen the noblewoman riding naked. This legend has inspired many artists in different fields, and nowadays its heroine is very famous and venerated. In particular, this essay focuses on the relation between this legend and compulsive looking (or scopophilia in two renowned films, Rear Window by Alfred Hitchcock, and Peeping Tom by Michael Powell.

  19. Molecular Chaperone Hsp70/Hsp90 Prepares the Mitochondrial Outer Membrane Translocon Receptor Tom71 for Preprotein Loading

    Energy Technology Data Exchange (ETDEWEB)

    Li, Jingzhi; Qian, Xinguo; Hu, Junbin; Sha, Bingdong; (UAB)

    2010-11-03

    The preproteins targeted to the mitochondria are transported through the translocase of the outer membrane complex. Tom70/Tom71 is a major surface receptor of the translocase of the outer membrane complex for mitochondrial preproteins. The preproteins are escorted to Tom70/Tom71 by molecular chaperones Hsp70 and Hsp90. Here we present the high resolution crystal structures of Tom71 and the protein complexes between Tom71 and the Hsp70/Hsp90 C terminus. The crystal structures indicate that Tom70/Tom71 may exhibit two distinct states. In the closed state, the N-terminal domain of Tom70/Tom71 partially blocks the preprotein-binding pocket. In the open state, the N-terminal domain moves away, and the preprotein-binding pocket is fully exposed. The complex formation between the C-terminal EEVD motif of Hsp70/Hsp90 and Tom71 could lock Tom71 in the open state where the preprotein-binding pocket of Tom71 is ready to receive preproteins. The interactions between Hsp70/Hsp90 and Tom71 N-terminal domain generate conformational changes that may increase the volume of the preprotein-binding pocket. The complex formation of Hsp70/Hsp90 and Tom71 also generates significant domain rearrangement within Tom71, which may position the preprotein-binding pocket closer to Hsp70/Hsp90 to facilitate the preprotein transfer from the molecular chaperone to Tom71. Therefore, molecular chaperone Hsp70/Hsp90 may function to prepare the mitochondrial outer membrane receptor Tom71 for preprotein loading.

  20. Electron tomogrophy of mitochondria after the arrest of protein import associated with Tom19 depletion

    NARCIS (Netherlands)

    Perkins, Guy A.; Renken, Christian W.; Klei, Ida J. van der; Ellisman, Mark H.; Neupert, Walter; Frey, Terrence G.

    In a mutant form of Neurospora crassa, in which sheltered RIP (repeat induced point mutation) was used to deplete Tom19, protein transport through the TOM/TIM pathway is arrested by the addition of p-fluorophenylalanine (FPA). Using intermediate-voltage electron tomography, we have generated

  1. 33 CFR 80.170 - Sandy Hook, NJ to Tom's River, NJ.

    Science.gov (United States)

    2010-07-01

    ... 33 Navigation and Navigable Waters 1 2010-07-01 2010-07-01 false Sandy Hook, NJ to Tom's River, NJ. 80.170 Section 80.170 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY INTERNATIONAL NAVIGATION RULES COLREGS DEMARCATION LINES Atlantic Coast § 80.170 Sandy Hook, NJ to Tom's River...

  2. 77 FR 51912 - Safety Zone; Tom Lyons Productions Fireworks, Long Island Sound, Sands Point, NY

    Science.gov (United States)

    2012-08-28

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF HOMELAND SECURITY Coast Guard 33 CFR Part 165 RIN 1625-AA00 Safety Zone; Tom Lyons Productions Fireworks, Long.... 165.T01-0618 to read as follows: Sec. 165.T01-0618 Safety Zone; Tom Lyons Productions Fireworks, Long...

  3. 33 CFR 80.501 - Tom's River, NJ to Cape May, NJ.

    Science.gov (United States)

    2010-07-01

    ... 33 Navigation and Navigable Waters 1 2010-07-01 2010-07-01 false Tom's River, NJ to Cape May, NJ. 80.501 Section 80.501 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY INTERNATIONAL NAVIGATION RULES COLREGS DEMARCATION LINES Fifth District § 80.501 Tom's River, NJ to Cape May, NJ...

  4. Meet TOM - the world's first open chest paediatric/adult manikin.

    Science.gov (United States)

    Dix, Ann

    2016-07-20

    Aged 15, TOM is a model patient. He has suffered more than his fair share of life-threatening events and never complains. But then TOM is not your average sick teenager - he is the world's first open chest paediatric/adult manikin.

  5. The TOM Complex of Amoebozoans: the Cases of the Amoeba Acanthamoeba castellanii and the Slime Mold Dictyostelium discoideum.

    Science.gov (United States)

    Wojtkowska, Małgorzata; Buczek, Dorota; Stobienia, Olgierd; Karachitos, Andonis; Antoniewicz, Monika; Slocinska, Małgorzata; Makałowski, Wojciech; Kmita, Hanna

    2015-07-01

    Protein import into mitochondria requires a wide variety of proteins, forming complexes in both mitochondrial membranes. The TOM complex (translocase of the outer membrane) is responsible for decoding of targeting signals, translocation of imported proteins across or into the outer membrane, and their subsequent sorting. Thus the TOM complex is regarded as the main gate into mitochondria for imported proteins. Available data indicate that mitochondria of representative organisms from across the major phylogenetic lineages of eukaryotes differ in subunit organization of the TOM complex. The subunit organization of the TOM complex in the Amoebozoa is still elusive, so we decided to investigate its organization in the soil amoeba Acanthamoeba castellanii and the slime mold Dictyostelium discoideum. They represent two major subclades of the Amoebozoa: the Lobosa and Conosa, respectively. Our results confirm the presence of Tom70, Tom40 and Tom7 in the A. castellanii and D. discoideum TOM complex, while the presence of Tom22 and Tom20 is less supported. Interestingly, the Tom proteins display the highest similarity to Opisthokonta cognate proteins, with the exception of Tom40. Thus representatives of two major subclades of the Amoebozoa appear to be similar in organization of the TOM complex, despite differences in their lifestyle. Copyright © 2015 The Authors. Published by Elsevier GmbH.. All rights reserved.

  6. Comparison of TOMS and AVHRR imagery of volcanic clouds

    Science.gov (United States)

    Rose, William I.

    1994-01-01

    This project consisted of merging volcanic cloud data from initial studies from TOMS and AVHRR sensors. Because of the different data acquisition platforms and processing algorithms and formats, the combination of the two data required special consideration. Once the registration technique was perfected, several eruptions with data from both sensors were studied. The conclusion showed that, from the initial work, the positions of the volcanic clouds as detected by the two sensors are very similar. Because the AVHRR algorithm is now capable of retrieving masses of ash and sulfate aerosol, the capability of comparing data from the two sensors now allows changes in SO2, H2SO4, and silicated ash in drifting clouds to be described. The results of this study culminated in several presentations, and a master's thesis, which in turn was converted into a paper submitted to the Journal of Geophysical Research. Abstracts of two presentations are attached.

  7. A Body that Matters: Tom Kilroy's Talbot's Box

    Directory of Open Access Journals (Sweden)

    Alexandra Poulain

    2014-01-01

    Full Text Available This paper looks at Tom Kilroy’s play Talbot Box, and argues that it resorts to the tropes of the Passion narrative, revisited by ex-centric mystic Matt Talbot, to expose the homogenising, normalising and exploitative efforts of the Catholic Church, a powerful institution which is shown to work in collusion with the forces of capitalism. Using a grotesque, often farcical dramaturgy, the play displays the joint attempts of ecclesiastical and temporal powers to appropriate Matt Talbot’s private performance of the Christian Passion for their own purposes, as well as the ways in which he resists instrumentalization by submitting himself to a radical form of bodily exposure. The play thus invents its own version of a theatre of cruelty in order to accommodate a mystical experience which lies beyond the reach of realistic representation. 

  8. The TOM complex is involved in the release of superoxide anion from mitochondria.

    Science.gov (United States)

    Budzińska, Małgorzata; Gałgańska, Hanna; Karachitos, Andonis; Wojtkowska, Małgorzata; Kmita, Hanna

    2009-08-01

    Available data indicate that superoxide anion (O(2)(*-) ) is released from mitochondria, but apart from VDAC (voltage dependent anion channel), the proteins involved in its transport across the mitochondrial outer membrane still remain elusive. Using mitochondria of the yeast Saccharomyces cerevisiae mutant depleted of VDAC (Deltapor1 mutant) and the isogenic wild type, we studied the role of the TOM complex (translocase of the outer membrane) in the efflux of O(2)(*-) from the mitochondria. We found that blocking the TOM complex with the fusion protein pb(2)-DHFR decreased O(2)(*-) release, particularly in the case of Deltapor1 mitochondria. We also observed that the effect of the TOM complex blockage on O(2)(*-) release from mitochondria coincided with the levels of O(2)(*-) release as well as with levels of Tom40 expression in the mitochondria. Thus, we conclude that the TOM complex participates in O(2)(*-) release from mitochondria.

  9. Measuring theory of mind in children. Psychometric properties of the ToM Storybooks.

    Science.gov (United States)

    Blijd-Hoogewys, E M A; van Geert, P L C; Serra, M; Minderaa, R B

    2008-11-01

    Although research on Theory-of-Mind (ToM) is often based on single task measurements, more comprehensive instruments result in a better understanding of ToM development. The ToM Storybooks is a new instrument measuring basic ToM-functioning and associated aspects. There are 34 tasks, tapping various emotions, beliefs, desires and mental-physical distinctions. Four studies on the validity and reliability of the test are presented, in typically developing children (n = 324, 3-12 years) and children with PDD-NOS (n = 30). The ToM Storybooks have good psychometric qualities. A component analysis reveals five components corresponding with the underlying theoretical constructs. The internal consistency, test-retest reliability, inter-rater reliability, construct validity and convergent validity are good. The ToM Storybooks can be used in research as well as in clinical settings.

  10. Plasticity of TOM complex assembly in skeletal muscle mitochondria in response to chronic contractile activity.

    Science.gov (United States)

    Joseph, Anna-Maria; Hood, David A

    2012-03-01

    We investigated the assembly of the TOM complex within skeletal muscle under conditions of chronic contractile activity-induced mitochondrial biogenesis. Tom40 import into mitochondria was increased by chronic contractile activity, as was its time-dependent assembly into the TOM complex. These changes coincided with contractile activity-induced augmentations in the expression of key protein import machinery components Tim17, Tim23, and Tom22, as well as the cytosolic chaperone Hsp90. These data indicate the adaptability of the TOM protein import complex and suggest a regulatory role for the assembly of this complex in exercise-induced mitochondrial biogenesis. Copyright © 2011 Elsevier B.V. and Mitochondria Research Society. All rights reserved. All rights reserved.

  11. 77 FR 57477 - Delegation of Certain Functions and Authority Under Section 5(a) of the Tom Lantos Block Burmese...

    Science.gov (United States)

    2012-09-17

    ... Authority Under Section 5(a) of the Tom Lantos Block Burmese Junta's Anti-Democratic Efforts Act of 2008 #0..., 2012 Delegation of Certain Functions and Authority Under Section 5(a) of the Tom Lantos Block Burmese... delegate to you the functions and authority conferred upon the President by section 5(a)(2) of the Tom...

  12. Structural features and inactivation of coagulation proteases of a sulfated polysaccharidic fraction from Caulerpa cupressoides var. lycopodium (Caulerpaceae, Chlorophyta - doi: 10.4025/actascitechnol.v35i4.16709

    Directory of Open Access Journals (Sweden)

    José Ariévilo Gurgel Rodrigues

    2013-10-01

    Full Text Available Studies on biopolymers from macroalgae suggested sulfated polysaccharides (SPs as research agents to investigate events related to haemostasis. Caulerpa cupressoides var. lycopodium is a marine green alga containing three SPs fractions (SP1, SP2 and SP3. SP2 had anticoagulant (in vitro and anti- and prothrombotic (in vivo actions; however, its effect on the coagulation system is not fully understood. This study aimed to determine the infrared (IR spectroscopy, chemical composition (CC, elemental microanalysis (EM, molecular weight (MW and the effect on coagulation proteases of SP2. The presence of sulfate ester, galactose-6-sulfate, uronic acid and glycoside linkages for IR spectrum; contents of sulfate (28%, total sugars (40% and uronic acids (7.18% for CC; and content of carbon (21.98%, sulfate (4.27%, nitrogen (1.3% and hydrogen (4.86% for EM were obtained. The average molecular weights of four different SPs (SP-1, SP-2, SP-3 and SP-4 subfractions from the SP2 ranged from ~ 8 to >100 kDa. SP2 was tested on coagulation proteases (thrombin and factor Xa in the presence of antithrombin (AT and heparin cofactor II (HCII using human plasma, being both thrombin and factor Xa target proteases inhibited, but requiring a concentration of about 2.5-fold higher of HCII than the thrombin inactivation by AT.   

  13. In vivo toxicological evaluation of crude sulfated polysaccharide from the green seaweed Caulerpa cupressoides var. lycopodium in Swiss mice - doi: 10.4025/actascitechnol.v35i4.15699

    Directory of Open Access Journals (Sweden)

    José Ariévilo Gurgel Rodrigues

    2013-10-01

    Full Text Available Seaweeds are widely consumed as vegetables and medicinal products. The green seaweed Caulerpa cupressoides var. lycopodium sulfated polysaccharides (SPs demonstrated anticoagulant (in vitro and anti- and prothrombotic (in vivo effects. However, their toxicity in vivo has not been fully determined. This study evaluated their toxicity in vivo in male Swiss mice. Animals (20-26 g, six group-1 received crude SP (9 mg kg-1, i.p. or 0.9% saline (0.1 mL 10 g-1, i.p. for 14 consecutive days, and then analyzed the wet weight of animal’s body organs-1 and biochemical/hematological parameters. Histopathological evaluation was also performed related to crude SP treatment. The results showed that crude SP did not cause toxicity and mortality. Regarding the biochemical analyses, crude SP did not lead to hepatic or renal dysfunctions, but affected (p 3 µL-1 compared with the control (969.75 ± 0.51 × 103 µL-1 according to the hematological evaluation. Although histological changes in the liver and kidney have occurred, results suggested reversibility. The increased spleen size (p C. cupressoides could represent safe pharmacological tool in future studies on immunomodulation and thrombosis in vivo.   

  14. Tecnología, servicios y cooperación. La experiencia de la Biblioteca Tomás Navarro Tomás del CSIC

    OpenAIRE

    2016-01-01

    La biblioteca Tomás Navarro Tomás (BTNT) es una biblioteca especializada al servicio de la investigación en Ciencias Humanas y Sociales dependiente del Consejo Superior de Investigaciones Científicas. Fue creada en 2008 mediante la fusión de ocho bibliotecas con el objetivo de ofrecer una colección híbrida (física, electrónica y digital) y unos servicios adaptados a las necesidades del siglo XXI. En 2010 se incorporó el Archivo del Centro de Ciencias Humanas y Sociales del CSIC y con él nueva...

  15. AuTom: a novel automatic platform for electron tomography reconstruction

    KAUST Repository

    Han, Renmin

    2017-07-26

    We have developed a software package towards automatic electron tomography (ET): Automatic Tomography (AuTom). The presented package has the following characteristics: accurate alignment modules for marker-free datasets containing substantial biological structures; fully automatic alignment modules for datasets with fiducial markers; wide coverage of reconstruction methods including a new iterative method based on the compressed-sensing theory that suppresses the “missing wedge” effect; and multi-platform acceleration solutions that support faster iterative algebraic reconstruction. AuTom aims to achieve fully automatic alignment and reconstruction for electron tomography and has already been successful for a variety of datasets. AuTom also offers user-friendly interface and auxiliary designs for file management and workflow management, in which fiducial marker-based datasets and marker-free datasets are addressed with totally different subprocesses. With all of these features, AuTom can serve as a convenient and effective tool for processing in electron tomography.

  16. Tomás Cipriano de Mosquera. El pensamiento político del gran General

    Directory of Open Access Journals (Sweden)

    Guillermo Hernández de Alba

    1978-12-01

    Full Text Available La República ha celebrado, con la dignidad y el decoro correspondientes, el ilustre personaje, el primer centenario de la muerte del preclaro popayanejo Tomás Cipriano de Mosquera.

  17. Tallinna poeedid tuunivad linna / Tom-Olaf Urb, Paul Oja, Rainer Olbri

    Index Scriptorium Estoniae

    2016-01-01

    Tom-Olaf Urbi (pseud. Reket), DJ Paul Oja, Rainer Olbri (pseud. Metsakutsu), Henry Kõrvitsa (pseud. G-Enka), Uku Aropi (pseud. Suur Pada) mõtteid Tallinna linnaruumist. Tallinna teema nende loomingus

  18. Tallinna poeedid tuunivad linna / Tom-Olaf Urb, Paul Oja, Rainer Olbri

    Index Scriptorium Estoniae

    2016-01-01

    Tom-Olaf Urbi (pseud. Reket), DJ Paul Oja, Rainer Olbri (pseud. Metsakutsu), Henry Kõrvitsa (pseud. G-Enka), Uku Aropi (pseud. Suur Pada) mõtteid Tallinna linnaruumist. Tallinna teema nende loomingus

  19. São Tomé and Príncipe - Threshold

    Data.gov (United States)

    Millennium Challenge Corporation — This report is a summative evaluation of the Millennium Challenge Corporation's (MCC) Threshold Country Program (TCP) for São Tomé and Príncipe. The program was...

  20. Lateral release of proteins from the TOM complex into the outer membrane of mitochondria.

    Science.gov (United States)

    Harner, Max; Neupert, Walter; Deponte, Marcel

    2011-07-15

    The TOM complex of the outer membrane of mitochondria is the entry gate for the vast majority of precursor proteins that are imported into the mitochondria. It is made up by receptors and a protein conducting channel. Although precursor proteins of all subcompartments of mitochondria use the TOM complex, it is not known whether its channel can only mediate passage across the outer membrane or also lateral release into the outer membrane. To study this, we have generated fusion proteins of GFP and Tim23 which are inserted into the inner membrane and, at the same time, are spanning either the TOM complex or are integrated into the outer membrane. Our results demonstrate that the TOM complex, depending on sequence determinants in the precursors, can act both as a protein conducting pore and as an insertase mediating lateral release into the outer membrane.

  1. Comparison of TOMS retrievals and UVMRP measurements of surface spectral UV radiation in the United States

    Directory of Open Access Journals (Sweden)

    M. Xu

    2010-09-01

    Full Text Available Surface noontime spectral ultraviolet (UV irradiances during May-September of 2000–2004 from the total ozone mapping spectrometer (TOMS satellite retrievals are systematically compared with the ground measurements at 27 climatological sites maintained by the USDA UV-B Monitoring and Research Program. The TOMS retrievals are evaluated by two cloud screening methods and local air quality conditions to determine their bias dependencies on spectral bands, cloudiness, aerosol loadings, and air pollution. Under clear-sky conditions, TOMS retrieval biases vary from −3.4% (underestimation to 23.6% (overestimation. Averaged over all sites, the relative mean biases for 305, 311, 325, and 368 nm are respectively 15.4, 7.9, 7.6, and 7.0% (overestimation. The bias enhancement for 305 nm by approximately twice that of other bands likely results from absorption by gaseous pollutants (SO2, O3, and aerosols that are not included in the TOMS algorithm. For all bands, strong positive correlations of the TOMS biases are identified with aerosol optical depth, which explains nearly 50% of the variances of TOMS biases. The more restrictive in-situ cloud screening method reduces the biases by 3.4–3.9% averaged over all sites. This suggests that the TOMS biases from the in-situ cloud contamination may account for approximately 25% for 305 nm and 50% for other bands of the total bias. The correlation coefficients between total-sky and clear-sky biases across 27 sites are 0.92, 0.89, 0.83, and 0.78 for 305, 311, 325, and 368 nm, respectively. The results show that the spatial characteristics of the TOMS retrieval biases are systematic, representative of both clear and total-sky conditions.

  2. GOME total ozone and calibration error derived using Version 8 TOMS Algorithm

    Science.gov (United States)

    Gleason, J.; Wellemeyer, C.; Qin, W.; Ahn, C.; Gopalan, A.; Bhartia, P.

    2003-04-01

    The Global Ozone Monitoring Experiment (GOME) is a hyper-spectral satellite instrument measuring the ultraviolet backscatter at relatively high spectral resolution. GOME radiances have been slit averaged to emulate measurements of the Total Ozone Mapping Spectrometer (TOMS) made at discrete wavelengths and processed using the new TOMS Version 8 Ozone Algorithm. Compared to Differential Optical Absorption Spectroscopy (DOAS) techniques based on local structure in the Huggins Bands, the TOMS uses differential absorption between a pair of wavelengths including the local structure as well as the background continuum. This makes the TOMS Algorithm more sensitive to ozone, but it also makes the algorithm more sensitive to instrument calibration errors. While calibration adjustments are not needed for the fitting techniques like the DOAS employed in GOME algorithms, some adjustment is necessary when applying the TOMS Algorithm to GOME. Using spectral discrimination at near ultraviolet wavelength channels unabsorbed by ozone, the GOME wavelength dependent calibration drift is estimated and then checked using pair justification. In addition, the day one calibration offset is estimated based on the residuals of the Version 8 TOMS Algorithm. The estimated drift in the 2b detector of GOME is small through the first four years and then increases rapidly to +5% in normalized radiance at 331 nm relative to 385 nm by mid 2000. The 1b detector appears to be quite well behaved throughout this time period.

  3. Tom goodey: the father of nematology in britain.

    Science.gov (United States)

    Hooper, D J

    1994-01-01

    Tom Goodey O.B.E., D.Sc., F.R.S. is generally recognized as the Father of Nematology in Britain. Although his early postgraduate work was on soil protozoa, from 1920 he worked exclusively on nematodes. His first text book, Plant Parasitic Nematodes and the Diseases They Cause, published in 1933, was a notable landmark in the development of nematology (48). His second book Soil and Freshwater Nematodes (80) indicated his breadth of understanding of this vast group of animals. From 1921 until 1946 he was a member of the team working under Professor R.T. Leiper based for most of that time at the Institute of Agricultural Parasitology, Winches Farm, St. Albans, England. He was author, or coauthor, of 125 publications, which included the proposal of 9 new genera, 37 new species and 49 detailed redescriptions of nematodes. In 1947 he was made head of the newly formed Nematology Department at Rothamsted Experimental Station, where he stayed until his retirement in 1952. In his later years he struck up a very close friendship with Gerald Thorne, the American nematologist, with whom he exchanged ideas on techniques in hematology. In 1951, he was responsible for the very successful nematology symposium held in Harpenden, which marked the beginning of the biennial nematology symposia in Europe. As well as a very full and successful scientific career, he was also a professional singer with a fine tenor voice and he frequently performed for the theater, concert hall, and radio broadcasts under his stage name of Roger Clayson.

  4. Prevention of the ischemia-induced decrease in mitochondrial Tom20 content by ischemic preconditioning.

    Science.gov (United States)

    Boengler, Kerstin; Gres, Petra; Cabestrero, Alberto; Ruiz-Meana, Marisol; Garcia-Dorado, David; Heusch, Gerd; Schulz, Rainer

    2006-09-01

    Preserved mitochondrial function (respiration, calcium handling) and integrity (cytochrome c release) is central for cell survival following ischemia/reperfusion. Mitochondrial function also requires import of proteins from the cytosol via the translocase of the outer and inner membrane (TOM and TIM complexes). Since mitochondrial function following ischemia/reperfusion is better preserved by ischemic preconditioning (IP), we now investigated whether expression of parts of the import machinery is affected by ischemia/reperfusion without or with IP in vivo. We analyzed the mitochondrial content of the presequence receptor Tom20, the pore forming unit Tom40 and Tim23. Goettinger minipigs were subjected to 90 min of low-flow ischemia without or with preconditioning by 10 min ischemia and 15 min reperfusion. Mitochondria were isolated from the ischemic or preconditioned anterior wall of the left ventricle and from the control posterior wall. Infarct size was significantly reduced by IP (20.1 +/- 1.6% of area at risk (non-preconditioned) vs. 6.5 +/- 2.5% of area at risk (IP)). Using Western blot analysis, the ratio of Tom20 (normalized to Ponceau S) between mitochondria isolated from the anterior ischemic and posterior control wall was reduced (0.72 +/- 0.11, a.u., n = 8), whereas the mitochondrial Tom20 content was preserved by IP (1.17 +/- 0.16 a.u., n = 7, P < 0.05). The mitochondrial Tom40, Tim23 and adenine nucleotide transporter (ANT) contents were not significantly different between non-preconditioned and preconditioned myocardium. The preservation of the mitochondrial Tom20 protein level may contribute to the improved mitochondrial function after IP.

  5. Cooperation of TOM and TIM23 complexes during translocation of proteins into mitochondria.

    Science.gov (United States)

    Waegemann, Karin; Popov-Čeleketić, Dušan; Neupert, Walter; Azem, Abdussalam; Mokranjac, Dejana

    2015-03-13

    Translocation of the majority of mitochondrial proteins from the cytosol into mitochondria requires the cooperation of TOM and TIM23 complexes in the outer and inner mitochondrial membranes. The molecular mechanisms underlying this cooperation remain largely unknown. Here, we present biochemical and genetic evidence that at least two contacts from the side of the TIM23 complex play an important role in TOM-TIM23 cooperation in vivo. Tim50, likely through its very C-terminal segment, interacts with Tom22. This interaction is stimulated by translocating proteins and is independent of any other TOM-TIM23 contact known so far. Furthermore, the exposure of Tim23 on the mitochondrial surface depends not only on its interaction with Tim50 but also on the dynamics of the TOM complex. Destabilization of the individual contacts reduces the efficiency of import of proteins into mitochondria and destabilization of both contacts simultaneously is not tolerated by yeast cells. We conclude that an intricate and coordinated network of protein-protein interactions involving primarily Tim50 and also Tim23 is required for efficient translocation of proteins across both mitochondrial membranes. Copyright © 2014 Elsevier Ltd. All rights reserved.

  6. Functional refolding and characterization of two Tom40 isoforms from human mitochondria.

    Science.gov (United States)

    Mager, Frauke; Gessmann, Dennis; Nussberger, Stephan; Zeth, Kornelius

    2011-07-01

    Tom40 proteins represent an essential class of molecules which facilitate translocation of unfolded proteins from the cytosol into the mitochondrial intermembrane space. They are part of a high-molecular mass complex that forms the protein-conducting channel in outer mitochondrial membranes. This study concerns the recombinant expression, purification and folding of amino-terminally truncated variants of the two human Tom40 isoforms for structural biology experiments. Both CD and FTIR secondary structure analysis revealed a dominant beta-sheet structure and a short alpha-helical part for both proteins together with a high thermal stability. Two secondary structure elements can be denatured independently. Reconstitution of the recombinant protein into planar lipid bilayers demonstrated ion channel activity similar to Tom40 purified from Neurospora crassa mitochondrial membranes, but conductivity fingerprints differ from the structurally closely related VDAC proteins.

  7. Interactions of mitochondrial presequence peptides with the mitochondrial outer membrane preprotein translocase TOM.

    Science.gov (United States)

    Romero-Ruiz, Mercedes; Mahendran, Kozhinjampara R; Eckert, Reiner; Winterhalter, Mathias; Nussberger, Stephan

    2010-08-04

    TOM protein-conducting channels serve as the main entry sites into mitochondria for virtually all mitochondrial proteins. When incorporated into lipid bilayers, they form large, relatively nonspecific ion channels that are blocked by peptides derived from mitochondrial precursor proteins. Using single-channel electrical recordings, we analyzed the interactions of mitochondrial presequence peptides with single TOM pores. The largest conductance state of the translocon represents the likely protein-conducting conformation of the channel. The frequency (but not the duration) of the polypeptide-induced blockage is strongly modulated by the substrate concentration. Structural differences between substrates are reflected in characteristic blockage frequencies and duration of blockage. To our knowledge, this study provides first quantitative data regarding the kinetics of polypeptide interaction with the mitochondrial TOM machinery. 2010 Biophysical Society. Published by Elsevier Inc. All rights reserved.

  8. Micro-Tom Tomato as an Alternative Plant Model System: Mutant Collection and Efficient Transformation.

    Science.gov (United States)

    Shikata, Masahito; Ezura, Hiroshi

    2016-01-01

    Tomato is a model plant for fruit development, a unique feature that classical model plants such as Arabidopsis and rice do not have. The tomato genome was sequenced in 2012 and tomato is becoming very popular as an alternative system for plant research. Among many varieties of tomato, Micro-Tom has been recognized as a model cultivar for tomato research because it shares some key advantages with Arabidopsis including its small size, short life cycle, and capacity to grow under fluorescent lights at a high density. Mutants and transgenic plants are essential materials for functional genomics research, and therefore, the availability of mutant resources and methods for genetic transformation are key tools to facilitate tomato research. Here, we introduce the Micro-Tom mutant database "TOMATOMA" and an efficient transformation protocol for Micro-Tom.

  9. The pro-apoptotic BH3-only protein Bim interacts with components of the translocase of the outer mitochondrial membrane (TOM.

    Directory of Open Access Journals (Sweden)

    Daniel O Frank

    Full Text Available The pro-apoptotic Bcl-2-family protein Bim belongs to the BH3-only proteins known as initiators of apoptosis. Recent data show that Bim is constitutively inserted in the outer mitochondrial membrane via a C-terminal transmembrane anchor from where it can activate the effector of cytochrome c-release, Bax. To identify regulators of Bim-activity, we conducted a search for proteins interacting with Bim at mitochondria. We found an interaction of Bim with Tom70, Tom20 and more weakly with Tom40, all components of the Translocase of the Outer Membrane (TOM. In vitro import assays performed on tryptically digested yeast mitochondria showed reduced Bim insertion into the outer mitochondrial membrane (OMM indicating that protein receptors may be involved in the import process. However, RNAi against components of TOM (Tom40, Tom70, Tom22 or Tom20 by siRNA, individually or in combination, did not consistently change the amount of Bim on HeLa mitochondria, either at steady state or upon de novo-induction. In support of this, the individual or combined knock-downs of TOM receptors also failed to alter the susceptibility of HeLa cells to Bim-induced apoptosis. In isolated yeast mitochondria, lack of Tom70 or the TOM-components Tom20 or Tom22 alone did not affect the import of Bim into the outer mitochondrial membrane. In yeast, expression of Bim can sensitize the cells to Bax-dependent killing. This sensitization was unaffected by the absence of Tom70 or by an experimental reduction in Tom40. Although thus the physiological role of the Bim-TOM-interaction remains unclear, TOM complex components do not seem to be essential for Bim insertion into the OMM. Nevertheless, this association should be noted and considered when the regulation of Bim in other cells and situations is investigated.

  10. The pro-apoptotic BH3-only protein Bim interacts with components of the translocase of the outer mitochondrial membrane (TOM).

    Science.gov (United States)

    Frank, Daniel O; Dengjel, Jörn; Wilfling, Florian; Kozjak-Pavlovic, Vera; Häcker, Georg; Weber, Arnim

    2015-01-01

    The pro-apoptotic Bcl-2-family protein Bim belongs to the BH3-only proteins known as initiators of apoptosis. Recent data show that Bim is constitutively inserted in the outer mitochondrial membrane via a C-terminal transmembrane anchor from where it can activate the effector of cytochrome c-release, Bax. To identify regulators of Bim-activity, we conducted a search for proteins interacting with Bim at mitochondria. We found an interaction of Bim with Tom70, Tom20 and more weakly with Tom40, all components of the Translocase of the Outer Membrane (TOM). In vitro import assays performed on tryptically digested yeast mitochondria showed reduced Bim insertion into the outer mitochondrial membrane (OMM) indicating that protein receptors may be involved in the import process. However, RNAi against components of TOM (Tom40, Tom70, Tom22 or Tom20) by siRNA, individually or in combination, did not consistently change the amount of Bim on HeLa mitochondria, either at steady state or upon de novo-induction. In support of this, the individual or combined knock-downs of TOM receptors also failed to alter the susceptibility of HeLa cells to Bim-induced apoptosis. In isolated yeast mitochondria, lack of Tom70 or the TOM-components Tom20 or Tom22 alone did not affect the import of Bim into the outer mitochondrial membrane. In yeast, expression of Bim can sensitize the cells to Bax-dependent killing. This sensitization was unaffected by the absence of Tom70 or by an experimental reduction in Tom40. Although thus the physiological role of the Bim-TOM-interaction remains unclear, TOM complex components do not seem to be essential for Bim insertion into the OMM. Nevertheless, this association should be noted and considered when the regulation of Bim in other cells and situations is investigated.

  11. Differential regulation of synaptic vesicle tethering and docking by UNC-18 and TOM-1

    Directory of Open Access Journals (Sweden)

    Elena O Gracheva

    2010-10-01

    Full Text Available The assembly of SNARE complexes between syntaxin, SNAP-25 and synaptobrevin is required to prime synaptic vesicles for fusion. Since Munc18 and tomosyn compete for syntaxin interactions, the interplay between these proteins is predicted to be important in regulating synaptic transmission. We explored this possibility, by examining genetic interactions between C. elegans unc-18(Munc18, unc-64(syntaxin and tom-1(tomosyn. We have previously demonstrated that unc-18 mutants have reduced synaptic transmission, whereas tom-1 mutants exhibit enhanced release. Here we show that the unc-18 mutant release defect is associated with loss of two morphologically distinct vesicle pools; those tethered within 25nm of the plasma membrane and those docked with the plasma membrane. In contrast, priming defective unc-13 mutants accumulate tethered vesicles, while docked vesicles are greatly reduced, indicating tethering is UNC-18-dependent and occurs in the absence of priming. C. elegans unc-64 mutants phenocopy unc-18 mutants, losing both tethered and docked vesicles, whereas overexpression of open syntaxin preferentially increases vesicle docking, suggesting UNC-18/closed syntaxin interactions are responsible for vesicle tethering. Given the competition between vertebrate tomosyn and Munc18, for syntaxin binding, we hypothesized that C. elegans TOM-1 may inhibit both UNC-18-dependent vesicle targeting steps. Consistent with this hypothesis, tom-1 mutants exhibit enhanced UNC-18 plasma membrane localization and a concomitant increase in both tethered and docked synaptic vesicles. Furthermore, in tom-1;unc-18 double mutants the docked, primed vesicle pool is preferentially rescued relative to unc-18 single mutants. Together these data provide evidence for the differential regulation of two vesicle targeting steps by UNC-18 and TOM-1 through competitive interactions with syntaxin

  12. Differential Regulation of Synaptic Vesicle Tethering and Docking by UNC-18 and TOM-1.

    Science.gov (United States)

    Gracheva, Elena O; Maryon, Ed B; Berthelot-Grosjean, Martine; Richmond, Janet E

    2010-01-01

    The assembly of SNARE complexes between syntaxin, SNAP-25 and synaptobrevin is required to prime synaptic vesicles for fusion. Since Munc18 and tomosyn compete for syntaxin interactions, the interplay between these proteins is predicted to be important in regulating synaptic transmission. We explored this possibility, by examining genetic interactions between C. elegans unc-18(Munc18), unc-64(syntaxin) and tom-1(tomosyn). We have previously demonstrated that unc-18 mutants have reduced synaptic transmission, whereas tom-1 mutants exhibit enhanced release. Here we show that the unc-18 mutant release defect is associated with loss of two morphologically distinct vesicle pools; those tethered within 25 nm of the plasma membrane and those docked with the plasma membrane. In contrast, priming defective unc-13 mutants accumulate tethered vesicles, while docked vesicles are greatly reduced, indicating tethering is UNC-18-dependent and occurs in the absence of priming. C. elegans unc-64 mutants phenocopy unc-18 mutants, losing both tethered and docked vesicles, whereas overexpression of open syntaxin preferentially increases vesicle docking, suggesting UNC-18/closed syntaxin interactions are responsible for vesicle tethering. Given the competition between vertebrate tomosyn and Munc18, for syntaxin binding, we hypothesized that C. elegans TOM-1 may inhibit both UNC-18-dependent vesicle targeting steps. Consistent with this hypothesis, tom-1 mutants exhibit enhanced UNC-18 plasma membrane localization and a concomitant increase in both tethered and docked synaptic vesicles. Furthermore, in tom-1;unc-18 double mutants the docked, primed vesicle pool is preferentially rescued relative to unc-18 single mutants. Together these data provide evidence for the differential regulation of two vesicle targeting steps by UNC-18 and TOM-1 through competitive interactions with syntaxin.

  13. Genome-wide analysis of intraspecific DNA polymorphism in 'Micro-Tom', a model cultivar of tomato (Solanum lycopersicum).

    Science.gov (United States)

    Kobayashi, Masaaki; Nagasaki, Hideki; Garcia, Virginie; Just, Daniel; Bres, Cécile; Mauxion, Jean-Philippe; Le Paslier, Marie-Christine; Brunel, Dominique; Suda, Kunihiro; Minakuchi, Yohei; Toyoda, Atsushi; Fujiyama, Asao; Toyoshima, Hiromi; Suzuki, Takayuki; Igarashi, Kaori; Rothan, Christophe; Kaminuma, Eli; Nakamura, Yasukazu; Yano, Kentaro; Aoki, Koh

    2014-02-01

    Tomato (Solanum lycopersicum) is regarded as a model plant of the Solanaceae family. The genome sequencing of the tomato cultivar 'Heinz 1706' was recently completed. To accelerate the progress of tomato genomics studies, systematic bioresources, such as mutagenized lines and full-length cDNA libraries, have been established for the cultivar 'Micro-Tom'. However, these resources cannot be utilized to their full potential without the completion of the genome sequencing of 'Micro-Tom'. We undertook the genome sequencing of 'Micro-Tom' and here report the identification of single nucleotide polymorphisms (SNPs) and insertion/deletions (indels) between 'Micro-Tom' and 'Heinz 1706'. The analysis demonstrated the presence of 1.23 million SNPs and 0.19 million indels between the two cultivars. The density of SNPs and indels was high in chromosomes 2, 5 and 11, but was low in chromosomes 6, 8 and 10. Three known mutations of 'Micro-Tom' were localized on chromosomal regions where the density of SNPs and indels was low, which was consistent with the fact that these mutations were relatively new and introgressed into 'Micro-Tom' during the breeding of this cultivar. We also report SNP analysis for two 'Micro-Tom' varieties that have been maintained independently in Japan and France, both of which have served as standard lines for 'Micro-Tom' mutant collections. Approximately 28,000 SNPs were identified between these two 'Micro-Tom' lines. These results provide high-resolution DNA polymorphic information on 'Micro-Tom' and represent a valuable contribution to the 'Micro-Tom'-based genomics resources.

  14. Tom Rüütel: Tööandjal on igal juhul kasud sees / intervjueerinud Helen Kask

    Index Scriptorium Estoniae

    Rüütel, Tom

    2013-01-01

    Kui oluliseks peab Tom töötamist ning millisena näeb ta tööandjate suhtumst erivajadusega töötajasse? Millised on Tomi mõtted seoses töövõimetoetuse (TVK) reformiga? Tom Rüütel õpib Tallinna Ülikoolis magistrantuuri teisel kursusel rakenduslikku sotsiaaltööd

  15. Training Preschoolers on First-Order False Belief Understanding: Transfer on Advanced ToM Skills and Metamemory

    Science.gov (United States)

    Lecce, Serena; Bianco, Federica; Demicheli, Patrizia; Cavallini, Elena

    2014-01-01

    This study investigated the relation between theory of mind (ToM) and metamemory knowledge using a training methodology. Sixty-two 4- to 5-year-old children were recruited and randomly assigned to one of two training conditions: A first-order false belief (ToM) and a control condition. Intervention and control groups were equivalent at pretest for…

  16. Exploratory study of the association between insight and Theory of Mind (ToM) in stable schizophrenia patients.

    Science.gov (United States)

    Pousa, Esther; Duñó, Rosó; Blas Navarro, J; Ruiz, Ada I; Obiols, Jordi E; David, Anthony S

    2008-05-01

    Poor insight and impairment in Theory of Mind (ToM) reasoning are common in schizophrenia, predicting poorer clinical and functional outcomes. The present study aimed to explore the relationship between these phenomena. 61 individuals with a DSM-IV diagnosis of schizophrenia during a stable phase were included. ToM was assessed using a picture sequencing task developed by Langdon and Coltheart (1999), and insight with the Scale to Assess Unawareness of Mental Disorder (SUMD; Amador et al., 1993). Multivariate linear regression analysis was carried out to estimate the predictive value of insight on ToM, taking into account several possible confounders and interaction variables. No direct significant associations were found between any of the insight dimensions and ToM using bivariate analysis. However, a significant linear regression model which explained 48% of the variance in ToM was revealed in the multivariate analysis. This included the 5 insight dimensions and 3 interaction variables. Misattribution of symptoms--in aware patients with age at onset >20 years--and unawareness of need for medication--in patients with GAF >60--were significantly predictive of better ToM. Insight and ToM are two complex and distinct phenomena in schizophrenia. Relationships between them are mediated by psychosocial, clinical, and neurocognitive variables. Intact ToM may be a prerequisite for aware patients to attribute their symptoms to causes other than mental illness, which could in turn be associated with denial of need for medication.

  17. Tom Rüütel: Tööandjal on igal juhul kasud sees / intervjueerinud Helen Kask

    Index Scriptorium Estoniae

    Rüütel, Tom

    2013-01-01

    Kui oluliseks peab Tom töötamist ning millisena näeb ta tööandjate suhtumst erivajadusega töötajasse? Millised on Tomi mõtted seoses töövõimetoetuse (TVK) reformiga? Tom Rüütel õpib Tallinna Ülikoolis magistrantuuri teisel kursusel rakenduslikku sotsiaaltööd

  18. Sam37 is crucial for formation of the mitochondrial TOM-SAM supercomplex, thereby promoting β-barrel biogenesis.

    Science.gov (United States)

    Wenz, Lena-Sophie; Ellenrieder, Lars; Qiu, Jian; Bohnert, Maria; Zufall, Nicole; van der Laan, Martin; Pfanner, Nikolaus; Wiedemann, Nils; Becker, Thomas

    2015-09-28

    Biogenesis of mitochondrial β-barrel proteins requires two preprotein translocases, the general translocase of the outer membrane (TOM) and the sorting and assembly machinery (SAM). TOM and SAM form a supercomplex that promotes transfer of β-barrel precursors. The SAM core complex contains the channel protein Sam50, which cooperates with Sam35 in precursor recognition, and the peripheral membrane protein Sam37. The molecular function of Sam37 has been unknown. We report that Sam37 is crucial for formation of the TOM-SAM supercomplex. Sam37 interacts with the receptor domain of Tom22 on the cytosolic side of the mitochondrial outer membrane and links TOM and SAM complexes. Sam37 thus promotes efficient transfer of β-barrel precursors to the SAM complex. We conclude that Sam37 functions as a coupling factor of the translocase supercomplex of the mitochondrial outer membrane. © 2015 Wenz et al.

  19. Tom Swift’s Three Inventions of Television: Media History and the Technological Imaginary

    NARCIS (Netherlands)

    Galili, Doron

    2015-01-01

    abstractThis article draws on fictional depiction of television in three novels in the Tom Swift series of boys' books, published in 1914, 1928, and 1933, in attempt to come to terms with different aspects of what sociologist of technology call the “technological imaginary” of television. As the nov

  20. Camus' Actor as Tom Stoppard's Player; A Key to Interpreting "Rosencrantz and Guildenstern Are Dead."

    Science.gov (United States)

    Zivanovic, Judith

    An examination of Albert Camus' definition of the actor in "The Myth on Sisyphus" helps to illuminate the character and role of The Player in Tom Stoppard's play and, hence, to bring light to an understanding of the philosophy of the play itself. The actor, for Camus, reveals our mortality in the face of the absurdity of our mortality,…

  1. The Decade Ahead: Inquire, Innovate, Impact. Tomás Rivera Lecture Series

    Science.gov (United States)

    Pacheco, Manuel T.

    2015-01-01

    In the 2015 Tomás Rivera lecture, Manuel T. Pacheco, President Emeritus of the University of Missouri System and the University of Arizona, discusses the importance of representing the Hispanic American population proportionately among college students, faculty, staff, and administration in higher education.

  2. Samuel Langhorne Clemens: A Centennial for Tom Sawyer; An Annotated, Selected Bibliography.

    Science.gov (United States)

    Haviland, Virginia, Comp.; Coughlan, Margaret N., Comp.

    This annotated bibliography, prepared by the Children's Book Section of the Library of Congress to celebrate the centennial of "The Adventures of Tom Sawyer," lists editions of the Mark Twain classics most widely read by young people, biographical or autobiographical and travel works significant for relevent background, and miscellaneous items…

  3. Collateral Damage: Veterans and Domestic Violence in Mari Sandoz's "The Tom-Walker"

    Science.gov (United States)

    Bahr, Kathy

    2010-01-01

    "The Tom-Walker" combines the best of Sandoz's realism with her worst attempts at moralizing. Unable to divine exactly what political configuration right-wing post-World War II sentiments might take, Sandoz nevertheless feared a fascist uprising in this country. Perhaps because these concerns dominated her thoughts at the time, she allowed her…

  4. Hydrology and Coastal Morphology at São Tomé

    NARCIS (Netherlands)

    Giardino, A.; Bettencourt, S.; Carvalho, A.; Filatova, Tatiana; de Keizer, O.; Schellekens, J.; Ottow, B.

    2012-01-01

    The Democratic Republic of São Tomé and Principe is an archipelago comprised of two main islands and several islets located in the Gulf of Guinea 350 km off the west coast of Africa. Villages of in the archipelago are built close to the coastline and have historically suffered from high rates of

  5. Best Practices Case Study: Tom Walsh and Co. - New Columbus, Portland, OR

    Energy Technology Data Exchange (ETDEWEB)

    none,

    2010-09-01

    Case study of Tom Walsh, who achieved 50% in heating and cooling energy savings over the 2004 IECC with advanced framing, superior air sealing, extra insulation, and ducts in conditioned space. Surface water runoff in the large urban rebuild development was handled with pervious pavers, swales, retention of existing trees, and green spaces.

  6. An Interview Forum on Interlibrary Loan/Document Delivery with Lynn Wiley and Tom Delaney

    Science.gov (United States)

    Hasty, Douglas F.

    2003-01-01

    The Virginia Boucher-OCLC Distinguished ILL Librarian Award is the most prestigious commendation given to practitioners in the field. The following questions about ILL were posed to the two most recent recipients of the Boucher Award: Tom Delaney (2002), Coordinator of Interlibrary Loan Services at Colorado State University and Lynn Wiley (2001),…

  7. Distinct forms of mitochondrial TOM-TIM supercomplexes define signal-dependent states of preprotein sorting.

    Science.gov (United States)

    Chacinska, Agnieszka; van der Laan, Martin; Mehnert, Carola S; Guiard, Bernard; Mick, David U; Hutu, Dana P; Truscott, Kaye N; Wiedemann, Nils; Meisinger, Chris; Pfanner, Nikolaus; Rehling, Peter

    2010-01-01

    Mitochondrial import of cleavable preproteins occurs at translocation contact sites, where the translocase of the outer membrane (TOM) associates with the presequence translocase of the inner membrane (TIM23) in a supercomplex. Different views exist on the mechanism of how TIM23 mediates preprotein sorting to either the matrix or inner membrane. On the one hand, two TIM23 forms were proposed, a matrix transport form containing the presequence translocase-associated motor (PAM; TIM23-PAM) and a sorting form containing Tim21 (TIM23(SORT)). On the other hand, it was reported that TIM23 and PAM are permanently associated in a single-entity translocase. We have accumulated distinct transport intermediates of preproteins to analyze the translocases in their active, preprotein-carrying state. We identified two different forms of active TOM-TIM23 supercomplexes, TOM-TIM23(SORT) and TOM-TIM23-PAM. These two supercomplexes do not represent separate pathways but are in dynamic exchange during preprotein translocation and sorting. Depending on the signals of the preproteins, switches between the different forms of supercomplex and TIM23 are required for the completion of preprotein import.

  8. SIM PlanetQuest: The TOM-3 (Thermo-Optical-Mechanical) Siderostat Mirror Test

    Science.gov (United States)

    Phillips, Charles J.

    2006-01-01

    This slide presentation reviews the Space Interferometry Mission (SIM) PlanetQuest mission. It describes the mission, shows diagrams of the instrument, the collector bays, the Siderostat mirrors, the COL bay thermal environment, the TOM-3 replicating COL Bay Environment, the thermal hardware for the SID heater control, and the results of the test are shown

  9. Systematic Comparison of Brain Imaging Meta-Analyses of ToM with vPT.

    Science.gov (United States)

    Arora, Aditi; Schurz, Matthias; Perner, Josef

    2017-01-01

    In visual perspective taking (vPT) one has to concern oneself with what other people see and how they see it. Since seeing is a mental state, developmental studies have discussed vPT within the domain of "theory of mind (ToM)" but imaging studies have not treated it as such. Based on earlier results from several meta-analyses, we tested for the overlap of visual perspective taking studies with 6 different kinds of ToM studies: false belief, trait judgments, strategic games, social animations, mind in the eyes, and rational actions. Joint activation was observed between the vPT task and some kinds of ToM tasks in regions involving the left temporoparietal junction (TPJ), anterior precuneus, left middle occipital gyrus/extrastriate body area (EBA), and the left inferior frontal and precentral gyrus. Importantly, no overlap activation was found for the vPT tasks with the joint core of all six kinds of ToM tasks. This raises the important question of what the common denominator of all tasks that fall under the label of "theory of mind" is supposed to be if visual perspective taking is not one of them.

  10. Azoospermia with variable testicular histology after 7 months of treatment with a deslorelin implant in toms.

    NARCIS (Netherlands)

    Novotny, R.; Vitasek, R.; Bartoskova, A.; Cizek, P.; Prinosilova, P.; Novakova, K.

    2015-01-01

    The main aim of the study was to assess whether the longer use of a GnRH-agonist implant (deslorelin 4.7 mg, Suprelorin) in toms would lead to the suppression of spermatogenesis comparable with histologic appearance in juvenile animals as was previously described in dogs. The other aims were to moni

  11. Transcultural differences in brain activation patterns during theory of mind (ToM) task performance in Japanese and Caucasian participants.

    Science.gov (United States)

    Koelkebeck, Katja; Hirao, Kazuyuki; Kawada, Ryousaku; Miyata, Jun; Saze, Teruyasu; Ubukata, Shiho; Itakura, Shoji; Kanakogi, Yasuhiro; Ohrmann, Patricia; Bauer, Jochen; Pedersen, Anya; Sawamoto, Nobukatsu; Fukuyama, Hidenao; Takahashi, Hidehiko; Murai, Toshiya

    2011-01-01

    Theory of mind (ToM) functioning develops during certain phases of childhood. Factors such as language development and educational style seem to influence its development. Some studies that have focused on transcultural aspects of ToM development have found differences between Asian and Western cultures. To date, however, little is known about transcultural differences in neural activation patterns as they relate to ToM functioning. The aim of our study was to observe ToM functioning and differences in brain activation patterns, as assessed by functional magnetic resonance imaging (fMRI). This study included a sample of 18 healthy Japanese and 15 healthy Caucasian subjects living in Japan. We presented a ToM task depicting geometrical shapes moving in social patterns. We also administered questionnaires to examine empathy abilities and cultural background factors. Behavioral data showed no significant group differences in the subjects' post-scan descriptions of the movies. The imaging results displayed stronger activation in the medial prefrontal cortex (MPFC) in the Caucasian sample during the presentation of ToM videos. Furthermore, the task-associated activation of the MPFC was positively correlated with autistic and alexithymic features in the Japanese sample. In summary, our results showed evidence of culturally dependent sociobehavioral trait patterns, which suggests that they have an impact on brain activation patterns during information processing involving ToM.

  12. DIVERSITY OF PTERIDOPHYTES IN THE PROTECTED AREA OF VÂLSAN VALLEY

    Directory of Open Access Journals (Sweden)

    Liliana Cristina Soare

    2012-04-01

    Full Text Available In the Vâlsan Valley there are two categories of regions that have been declared protected areas: The Natural Reserve Vâlsan Valley, code 2125 and The protected natural area of community interest Vâlsan Valley, code ROSCI0268. The aim of the research was to identify the species of pteridophytes in the protected areas, a necessary step for the conservation of their diversity. Within the area researched 26 species of pteridophytes were determined. Specific diversity across the genera identified ranges from 5 to 1, thus: Equisetum (5, Asplenium (4, Dryopteris (4, Polystichum (3 and Huperzia, Lycopodium, Selaginella, Botrychium, Polypodium, Phegopteris, Athyrium, Cystopteris, Gymnocarpium, Matteuccia with only one species. Concerning the abundance of the species identified, the pteridoflora in the area researched is made up of frequent (73% and sporadic species (27%, such as Huperzia selago, Lycopodium annotinum, Botrychium multifidum, Asplenium scolopendrium, Matteuccia struthiopteris, Dryopteris expansa, Polystichum braunii.

  13. Theory of mind broad and narrow: reasoning about social exchange engages ToM areas, precautionary reasoning does not.

    Science.gov (United States)

    Ermer, Elsa; Guerin, Scott A; Cosmides, Leda; Tooby, John; Miller, Michael B

    2006-01-01

    Baron-Cohen (1995) proposed that the theory of mind (ToM) inference system evolved to promote strategic social interaction. Social exchange--a form of co-operation for mutual benefit--involves strategic social interaction and requires ToM inferences about the contents of other individuals' mental states, especially their desires, goals, and intentions. There are behavioral and neuropsychological dissociations between reasoning about social exchange and reasoning about equivalent problems tapping other, more general content domains. It has therefore been proposed that social exchange behavior is regulated by social contract algorithms: a domain-specific inference system that is functionally specialized for reasoning about social exchange. We report an fMRI study using the Wason selection task that provides further support for this hypothesis. Precautionary rules share so many properties with social exchange rules--they are conditional, deontic, and involve subjective utilities--that most reasoning theories claim they are processed by the same neurocomputational machinery. Nevertheless, neuroimaging shows that reasoning about social exchange activates brain areas not activated by reasoning about precautionary rules, and vice versa. As predicted, neural correlates of ToM (anterior and posterior temporal cortex) were activated when subjects interpreted social exchange rules, but not precautionary rules (where ToM inferences are unnecessary). We argue that the interaction between ToM and social contract algorithms can be reciprocal: social contract algorithms requires ToM inferences, but their functional logic also allows ToM inferences to be made. By considering interactions between ToM in the narrower sense (belief-desire reasoning) and all the social inference systems that create the logic of human social interaction--ones that enable as well as use inferences about the content of mental states--a broader conception of ToM may emerge: a computational model embodying

  14. Structural elements of the mitochondrial preprotein-conducting channel Tom40 dissolved by bioinformatics and mass spectrometry.

    Science.gov (United States)

    Gessmann, Dennis; Flinner, Nadine; Pfannstiel, Jens; Schlösinger, Andrea; Schleiff, Enrico; Nussberger, Stephan; Mirus, Oliver

    2011-12-01

    Most mitochondrial proteins are imported into mitochondria from the cytosolic compartment. Proteins destined for the outer or inner membrane, the inter-membrane space, or the matrix are recognized and translocated by the TOM machinery containing the specialized protein import channel Tom40. The latter is a protein with β-barrel shape, which is suggested to have evolved from a porin-type protein. To obtain structural insights in the absence of a crystal structure the membrane topology of Tom40 from Neurospora crassa was determined by limited proteolysis combined with mass spectrometry. The results were interpreted on the basis of a structural model that has been generated for NcTom40 by using the structure of mouse VDAC-1 as a template and amino acid sequence information of approximately 270 different Tom40 and approximately 480 VDAC amino acid sequences for refinement. The model largely explains the observed accessible cleavage sites and serves as a structural basis for the investigation of physicochemical properties of the ensemble of our Tom40 sequence data set. By this means we discovered two conserved polar slides in the pore interior. One is possibly involved in the positioning of a pore-inserted helix; the other one might be important for mitochondrial pre-sequence peptide binding as it is only present in Tom40 but not in VDAC proteins. The outer surface of the Tom40 barrel reveals two conserved amino acid clusters. They may be involved in binding other components of the TOM complex or bridging components of the TIM machinery of the mitochondrial inner membrane.

  15. miR-126 is downregulated in cystic fibrosis airway epithelial cells and regulates TOM1 expression.

    LENUS (Irish Health Repository)

    Oglesby, Irene K

    2010-02-15

    Cystic fibrosis (CF) is one of the most common lethal genetic diseases in which the role of microRNAs has yet to be explored. Predicted to be regulated by miR-126, TOM1 (target of Myb1) has been shown to interact with Toll-interacting protein, forming a complex to regulate endosomal trafficking of ubiquitinated proteins. TOM1 has also been proposed as a negative regulator of IL-1beta and TNF-alpha-induced signaling pathways. MiR-126 is highly expressed in the lung, and we now show for the first time differential expression of miR-126 in CF versus non-CF airway epithelial cells both in vitro and in vivo. MiR-126 downregulation in CF bronchial epithelial cells correlated with a significant upregulation of TOM1 mRNA, both in vitro and in vivo when compared with their non-CF counterparts. Introduction of synthetic pre-miR-126 inhibited luciferase activity in a reporter system containing the full length 3\\'-untranslated region of TOM1 and resulted in decreased TOM1 protein production in CF bronchial epithelial cells. Following stimulation with LPS or IL-1beta, overexpression of TOM1 was found to downregulate NF-kappaB luciferase activity. Conversely, TOM1 knockdown resulted in a significant increase in NF-kappaB regulated IL-8 secretion. These data show that miR-126 is differentially regulated in CF versus non-CF airway epithelial cells and that TOM1 is a miR-126 target that may have an important role in regulating innate immune responses in the CF lung. To our knowledge, this study is the first to report of a role for TOM1 in the TLR2\\/4 signaling pathways and the first to describe microRNA involvement in CF.

  16. Tropospheric Ozone Pollution from Space: New Views from the TOMS (Total Ozone Mapping Spectrometer) Instrument

    Science.gov (United States)

    Thompson, Anne M.; Hudson, Robert D.; Frolov, Alexander D.; Witte, Jacquelyn C.; Kucsera, Tom L.; Einaudi, Franco (Technical Monitor)

    2000-01-01

    New products from the TOMS (Total Ozone Mapping Spectrometer) >satellite instrument can resolve pollution events in tropical and mid-latitudes, Over the past several years, we have developed tropospheric ozone data sets by two methods. The modified-residual technique [Hudson and Thompson, 1998; Thompson and Hudson, 1999] uses v. 7 TOMS total ozone and is applicable to tropical regimes in which the wave-one pattern in total ozone is observed. The TOMSdirect method [Hudson et at., 2000] represents a new algorithm that uses TOMS radiances to extract tropospheric ozone in regions of constant stratospheric ozone and tropospheric ozone displaying high mixing ratios and variability characteristic of pollution, Absorbing aerosols (dust and smoke; Herman et at., 1997 Hsu et al., 1999), a standard TOMS product, provide transport and/or source marker information to interpret tropospheric ozone. For the Nimbus 7/TOMS observing period (1979-1992), modified-residual TTO (tropical tropospheric ozone) appears as two maps/month at I-degree latitude 2-degree longitude resolution at a homepage and digital data are available (20S to 20N) by ftp at http://metosrv2. umd.edu/tropo/ 14y_data.d. Preliminary modified-residual TTO data from the operational Earth-Probe/TOMS (1996- present) are posted in near-real-time at the same website. Analyses with the new tropospheric ozone and aerosol data are illustrated by the following (I)Signals in tropical tropospheric ozone column and smoke amount during ENSO (El Nino-Southern Oscillation) events, e.g. 1982-1983 and the intense ENSO induced biomass fires of 1997-1998 over the Indonesian region [Thompson et a[, 2000a, Thompson and Hudson, 1999]. (2) Trends in tropospheric ozone and smoke aerosols in various tropical regions (Atlantic, Pacific, Africa, Brazil). No significant trends were found for ozone from1980-1990 [Thompson and Hudson, 19991 although smoke aerosols increased during the period [Hsu et al.,1999]. (3) Temporal and spatial offsets

  17. Instituciones microfinancieras y cajas de ahorro en Santo Tomás Hueyotlipan, Puebla/Microfinance institutions and savings banks in the town of Santo Tomás Hueyotlipan, Puebla

    National Research Council Canada - National Science Library

    Kristiano Raccanello; Gerardo Roldán-Bravo

    2014-01-01

    .... This paper, based on a sample drawn in the town of Santo Tomás Hueyotlipan (Puebla, Mexico), examines the participation of people in informal savings banks and their interaction with other informal financial intermediaries...

  18. Comparison of TOMS and AVHRR volcanic ssh retrievals from the August 1992 eruption of Mt. Spurr

    Science.gov (United States)

    Krotkov, N.A.; Torres, O.; Seftor, C.; Krueger, A.J.; Kostinski, A.; Rose, William I.; Bluth, G.J.S.; Schneider, D.; Schaefer, S.J.

    1999-01-01

    On August 19, 1992, the Advanced Very High Resolution Radiometer (AVHRR) onboard NOAA-12 and NASA's Total Ozone Mapping Spectrometer (TOMS) onboard the Nimbus-7 satellite simultaneously detected and mapped the ash cloud from the eruption of Mt. Spurr, Alaska. The spatial extent and geometry of the cloud derived from the two datasets are in good agreement and both AVHRR split window IR (11-12??m brightness temperature difference) and the TOMS UV Aerosol Index (0.34-0.38??m ultraviolet backscattering and absorption) methods give the same range of total cloud ash mass. Redundant methods for determination of ash masses in drifting volcanic clouds offer many advantages for potential application to the mitigation of aircraft hazards.

  19. Comparative morphometric study of shank bone in the tom (Meleagris gallopavo and local cock (Gallus banikaval

    Directory of Open Access Journals (Sweden)

    S. Al-Sadi

    2012-01-01

    Full Text Available The study was carried out on 20 legs of ten adult clinically and healthy local and Tom were obtained from Mosul local market, were divided into three groups; the first and second groups were subjected to gross feature regarding to shape, position, relationship of tibiotarsal and fibula in both birds also the length and diameters of shank bone while third group study morphological of muscles, blood and nerve supply of leg. The purpose of this study, this part of the limb is popularly known as the (drum stick, the bird in lowering its body flexes knee and hock joints and this passively tenses these tendons of leg which clamp the digits about the perch, and that is the much longer than the femur and, in spite of importance study to parameters of leg are more economic to choose breed of fertilization depend on the measurement, the outcome of this investigation may served as a guide for successful study of domestic birds in Iraq. The results include in both birds, the leg is consist of tibia fuses with tarsal element, forming tibiotarsus and fiblula articulates with the femur that in contrast to mammals. In Tom the tibia has two cnemial crest in proximal extremity and the distal extremity has tendinal groove, but in local cock it has one cnemial crest of proximal extremity, and it has two tendinal groove in the distal extremity, while hock joint in the Tom and local cock is an intertarsal joint that unites the tibiotarsus with the tarsometatarsus but the stiff joint is similar to that seen in mammals. The mean length of tibiotarsal in Tom 17.99±0.44 cm and the mean length of tibiotarsal in local coke 11.74±0.31 cm, the mean diameter of tibiotarsal in Tom 3.02±0.0021 cm proximal part, 2.21±0.005 cm middle part, 1.94±0.0021 cm distal part, but the mean diameter of tibiotarsal in local coke 2.86±0.048 cm proximal part, 2.02±0.067 cm middle part, 1.51±0.0022 cm distal part. While the mean length of fibula in Tom 11.62±0.21 cm and the mean length

  20. A Discussion of Nearshore Processes Research During and After the Tenure of Dr. Tom Kinder

    Science.gov (United States)

    Holman, R.

    2001-12-01

    The progress of science often evolves in a way that can depend surprisingly on the contributions of a few individuals. In very occasional cases, one or two scientists make critical breakthroughs that yield quantum leaps in understanding. In other cases, a single individual in a position of responsibility can foster a research environment that is highly productive for the entire community. In this talk, I will discuss the general evolution of nearshore processes research during the 1990's and earlier 2000's, the period of tenure of Tom Kinder as Program Manager at ONR. The focus will be on the inter-linked nature of the nearshore problem and how the advances of component disciplines affected each other. The talk will finish with a future look at nearshore science into the next decade. The influence of Tom, in his role as beneficent dictator, will be an underlying theme.

  1. Membrane-embedded C-terminal segment of rat mitochondrial TOM40 constitutes protein-conducting pore with enriched beta-structure.

    Science.gov (United States)

    Suzuki, Hiroyuki; Kadowaki, Tomoko; Maeda, Maki; Sasaki, Hiroyuki; Nabekura, Junichi; Sakaguchi, Masao; Mihara, Katsuyoshi

    2004-11-26

    TOM40 is the central component of the preprotein translocase of the mitochondrial outer membrane (TOM complex). We purified recombinant rat TOM40 (rTOM40), which was refolded in Brij35 after solubilization from inclusion bodies by guanidine HCl. rTOM40 (i) consisted of a 63% beta-sheet structure and (ii) bound a matrix-targeted preprotein with high affinity and partially translocated it into the rTOM40 pore. This partial translocation was inhibited by stabilization of the mature domain of the precursor. (iii) rTOM40 bound preprotein initially through ionic interactions, followed by salt-resistant non-ionic interactions, and (iv) exhibited presequence-sensitive, cation-specific channel activity in reconstituted liposomes. Based on the domain structure of rTOM40 deduced by protease treatment, we purified the elastase-resistant and membrane-embedded C-terminal segment (rTOM40(DeltaN165)) as a recombinant protein with 62% beta-structure that exhibited properties comparable with those of full-size rTOM40. We concluded that the membrane-embedded C-terminal half of rTOM40 constitutes the preprotein recognition domain with an enriched beta-structure, which forms the preprotein conducting pore containing a salt-sensitive cis-binding site and a salt-resistant trans-binding site.

  2. Cloth Ears at Work: Aural Elements in the Theatre Plays of Tom Stoppard

    OpenAIRE

    Sharp, Cameron Andrew

    2015-01-01

    This thesis investigates Tom Stoppard s inclusion of music and other aural effects (including juxtaposed silence) in his stage plays from 1967 to 2015. The analysis includes both diegetic and non-diegetic aural elements (the former being where aural elements are fixed within the narrative, and the latter being a form of commentary to the narrative, available to the audience but not to the on-stage characters). With particular focus on Rosencrantz and Guildenstern Are Dead, Travesties, Arcadia...

  3. Santo Tomás y los demás

    Directory of Open Access Journals (Sweden)

    Alfonso Rincón

    1988-10-01

    Full Text Available La filosofia del medioevo. VIII Coloquio de la Sociedad Colombiana de Filosofia. J.A. Díaz, J.P. Margot, A.L. Gómez, E. Lákatos, A. Cárdenas, G. Soto, D. Herrera, A. Papacchini, J. Zabalza. Biblioteca Colombiana de Filosofía, Universidad de Santo Tomás, Bogotá, 1987, 138 págs.

  4. Satellite Detection of Smoke Aerosols Over a Snow/Ice Surface by TOMS

    Science.gov (United States)

    Hsu, N. Christina; Herman, Jay R.; Gleason, J. F.; Torres, O.; Seftor, C. J.

    1998-01-01

    The use of TOMS (Total Ozone Mapping Spectrometer) satellite data demonstrates the recently developed technique of using satellite UV radiance measurements to detect absorbing tropospheric aerosols is effective over snow/ice surfaces. Instead of the traditional single wavelength (visible or infrared) method of measuring tropospheric aerosols, this method takes advantage of the wavelength dependent reduction in the backscattered radiance due to the presence of absorbing aerosols over snow/ice surfaces. An example of the resulting aerosol distribution derived from TOMS data is shown for an August 1998 event in which smoke generated by Canadian forest fires drifts over and across Greenland. As the smoke plume moved over Greenland, the TOMS observed 380 nm reflectivity over the snow/ice surface dropped drastically from 90-100% down to 30-40%. To study the effects of this smoke plume in both the UV and visible regions of the spectrum, we compared a smoke-laden spectrum taken over Greenland by the high spectral resolution (300 to 800 nm) GOME instrument with one that is aerosol-free. We also discuss the results of modeling the darkening effects of various types of absorbing aerosols over snow/ice surfaces using a radiative transfer code. Finally, we investigated the history of such events by looking at the nearly twenty year record of TOMS aerosol index measurements and found that there is a large interannual variability in the amount of smoke aerosols observed over Greenland. This information will be available for studies of radiation and transport properties in the Arctic.

  5. Occurrence of ozone anomalies over cloudy areas in TOMS version-7 level-2 data

    OpenAIRE

    Liu, X.; M.J. Newchurch; Kim, J. H.

    2003-01-01

    This study investigates anomalous ozone distributions over cloudy areas in Nimbus-7 (N7) and Earth-Probe (EP) TOMS version-7 data and analyzes the causes for ozone anomaly formation. A 5°-longitude by 5°-latitude region is defined to contain a Positive Ozone Anomaly (POA) or Negative Ozone Anomaly (NOA) if the correlation coefficient between total ozone and reflectivity is > 0.5 or

  6. O tom, tshto ushlo : [luuletused] / Aleksander Suuman ; Lühibiograafia: T. L. [Toomas Liiv

    Index Scriptorium Estoniae

    Suuman, Aleksander, 1927-2003

    1999-01-01

    Sisu: O tom, tshto ushlo ; "Gde-to dolzhno zhe bõt stshastje..." ; "Serõje lessa..." ; Zholtogolovõ ; "Teh iv serebristõh nelzja oboiti..." ; "Vzroslõje vkladtshinu pili..." ; "U nas tut, za Giperborejem..." / tlk. Svetlan Semenenko ; Odno hotshu skazat ; Los idjot / tlk. Boris Baljasnõi.Orig.: "Kusagil peab olema õnn..." ; Kullerkupud ; "Ei hõbepajust ma mööduda saand..." ; "Meil siin Hüperboreas..." ;

  7. Molecular biology and riddle of cancer: the ‘Tom & Jerry’ show

    Directory of Open Access Journals (Sweden)

    Md. Al Mamun

    2011-11-01

    Full Text Available From the conventional Bird’s eye, cancer initiation and metastasis are generally intended to be understood beneath the light of classical clonal genetic, epigenetic and cancer stem cell model. But inspite decades of investigation, molecular biology has shown hard success to give Eagle’s eye in unraveling the riddle of cancer. And it seems, tiring Tom runs in vague behind naughty Jerry.

  8. O tom, tshto ushlo : [luuletused] / Aleksander Suuman ; Lühibiograafia: T. L. [Toomas Liiv

    Index Scriptorium Estoniae

    Suuman, Aleksander, 1927-2003

    1999-01-01

    Sisu: O tom, tshto ushlo ; "Gde-to dolzhno zhe bõt stshastje..." ; "Serõje lessa..." ; Zholtogolovõ ; "Teh iv serebristõh nelzja oboiti..." ; "Vzroslõje vkladtshinu pili..." ; "U nas tut, za Giperborejem..." / tlk. Svetlan Semenenko ; Odno hotshu skazat ; Los idjot / tlk. Boris Baljasnõi.Orig.: "Kusagil peab olema õnn..." ; Kullerkupud ; "Ei hõbepajust ma mööduda saand..." ; "Meil siin Hüperboreas..." ;

  9. Implementation and Non-Destructive Evaluation of Composite Structural Shapes in the Tom's Creek Bridge

    OpenAIRE

    Hayes, M. D.; J. Haramis; Lesko, John J.; Cousins, Thomas E.; J.C.Duke; Weyers, Richard E.

    2000-01-01

    A bridge rehabilitation utilizing a hybrid fiber reinforced polymeric composite has been completed in Blacksburg, Virginia. This project involved replacing the superstructure in the Tom's Creek Bridge, a rural short-span traffic bridge with a timber deck and corroded steel girders, with a glue-laminated timber deck on composite girders. In order to verify the bridge design and to address construction issues prior to the rehabilitation, a full-scale mock-up of the bridge was built and tested i...

  10. Conservación de fondos en la Biblioteca Tomás Navarro Tomás, aplicación de la tecnología de sensores ambientales

    OpenAIRE

    Jiménez Martín, Alejandro; González Sarmiento, Francisco; Morillo Calero, María Jesús; Agua Martínez, Fernando; Peña Poza, Javier; Conde Moreno, Juan Felix; García Heras, Manuel; Villegas Broncano, María Ángeles; Palomar Sanz, Teresa

    2010-01-01

    El Grupo de Investigación de Arqueometría de Vidrios y Materiales Cerámicos (CERVITRUM) del Instituto de Historia del Centro de Ciencias Humanas y Sociales del CSIC, está realizando en las instalaciones de la Biblioteca Tomás Navarro Tomás (BTNT) un estudio de campo sobre las condiciones de conservación de los fondos documentales, aplicando una tecnología de sensores ambientales desarrollada por ellos mismos.

  11. Peeping at TOMs-Diverse Entry Gates to Mitochondria Provide Insights into the Evolution of Eukaryotes.

    Science.gov (United States)

    Mani, Jan; Meisinger, Chris; Schneider, André

    2016-02-01

    Mitochondria are essential for eukaryotic life and more than 95% of their proteins are imported as precursors from the cytosol. The targeting signals for this posttranslational import are conserved in all eukaryotes. However, this conservation does not hold true for the protein translocase of the mitochondrial outer membrane that serves as entry gate for essentially all precursor proteins. Only two of its subunits, Tom40 and Tom22, are conserved and thus likely were present in the last eukaryotic common ancestor. Tom7 is found in representatives of all supergroups except the Excavates. This suggests that it was added to the core of the translocase after the Excavates segregated from all other eukaryotes. A comparative analysis of the biochemically and functionally characterized outer membrane translocases of yeast, plants, and trypanosomes, which represent three eukaryotic supergroups, shows that the receptors that recognize the conserved import signals differ strongly between the different systems. They present a remarkable example of convergent evolution at the molecular level. The structural diversity of the functionally conserved import receptors therefore provides insight into the early evolutionary history of mitochondria. © The Author 2015. Published by Oxford University Press on behalf of the Society for Molecular Biology and Evolution. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

  12. RNAi screen in Drosophila cells reveals the involvement of the Tom complex in Chlamydia infection.

    Directory of Open Access Journals (Sweden)

    Isabelle Derré

    2007-10-01

    Full Text Available Chlamydia spp. are intracellular obligate bacterial pathogens that infect a wide range of host cells. Here, we show that C. caviae enters, replicates, and performs a complete developmental cycle in Drosophila SL2 cells. Using this model system, we have performed a genome-wide RNA interference screen and identified 54 factors that, when depleted, inhibit C. caviae infection. By testing the effect of each candidate's knock down on L. monocytogenes infection, we have identified 31 candidates presumably specific of C. caviae infection. We found factors expected to have an effect on Chlamydia infection, such as heparansulfate glycosaminoglycans and actin and microtubule remodeling factors. We also identified factors that were not previously described as involved in Chlamydia infection. For instance, we identified members of the Tim-Tom complex, a multiprotein complex involved in the recognition and import of nuclear-encoded proteins to the mitochondria, as required for C. caviae infection of Drosophila cells. Finally, we confirmed that depletion of either Tom40 or Tom22 also reduced C. caviae infection in mammalian cells. However, C. trachomatis infection was not affected, suggesting that the mechanism involved is C. caviae specific.

  13. Systematic Comparison of Brain Imaging Meta-Analyses of ToM with vPT

    Science.gov (United States)

    Schurz, Matthias; Perner, Josef

    2017-01-01

    In visual perspective taking (vPT) one has to concern oneself with what other people see and how they see it. Since seeing is a mental state, developmental studies have discussed vPT within the domain of “theory of mind (ToM)” but imaging studies have not treated it as such. Based on earlier results from several meta-analyses, we tested for the overlap of visual perspective taking studies with 6 different kinds of ToM studies: false belief, trait judgments, strategic games, social animations, mind in the eyes, and rational actions. Joint activation was observed between the vPT task and some kinds of ToM tasks in regions involving the left temporoparietal junction (TPJ), anterior precuneus, left middle occipital gyrus/extrastriate body area (EBA), and the left inferior frontal and precentral gyrus. Importantly, no overlap activation was found for the vPT tasks with the joint core of all six kinds of ToM tasks. This raises the important question of what the common denominator of all tasks that fall under the label of “theory of mind” is supposed to be if visual perspective taking is not one of them.

  14. Systematic Comparison of Brain Imaging Meta-Analyses of ToM with vPT

    Directory of Open Access Journals (Sweden)

    Aditi Arora

    2017-01-01

    Full Text Available In visual perspective taking (vPT one has to concern oneself with what other people see and how they see it. Since seeing is a mental state, developmental studies have discussed vPT within the domain of “theory of mind (ToM” but imaging studies have not treated it as such. Based on earlier results from several meta-analyses, we tested for the overlap of visual perspective taking studies with 6 different kinds of ToM studies: false belief, trait judgments, strategic games, social animations, mind in the eyes, and rational actions. Joint activation was observed between the vPT task and some kinds of ToM tasks in regions involving the left temporoparietal junction (TPJ, anterior precuneus, left middle occipital gyrus/extrastriate body area (EBA, and the left inferior frontal and precentral gyrus. Importantly, no overlap activation was found for the vPT tasks with the joint core of all six kinds of ToM tasks. This raises the important question of what the common denominator of all tasks that fall under the label of “theory of mind” is supposed to be if visual perspective taking is not one of them.

  15. Highlights from a Decade of OMI-TOMS Total Ozone Observations on EOS Aura

    Science.gov (United States)

    Haffner, David P.; Bhartia, Pawan K.; McPeters, Richard D.; Joiner, Joanna; Ziemke, Jerald R.; Vassilkov, Alexander; Labow, Gordon J.; Chiou, Er-Woon

    2014-01-01

    Total ozone measurements from OMI have been instrumental in meeting Aura science objectives. In the last decade, OMI has extended the length of the TOMS total ozone record to over 35 years to monitor stratospheric ozone recovery. OMI-TOMS total ozone measurements have also been combined synergistically with measurements from other Aura instruments and MLS in particular, which provides vertically resolved information that complements the total O3 mapping capability of OMI. With this combined approach, the EOS Aura platform has produced more accurate and detailed measurements of tropospheric ozone. This has led in turn to greater understanding of the sources and transport of tropospheric ozone as well as its radiative forcing effect. The combined use of OMI and MLS data was also vital to the analysis of the severe Arctic ozone depletion event of 2011. The quality of OMI-TOMS total O3 data used in these studies is the result of several factors: a mature and well-validated algorithm, the striking stability of the OMI instrument, and OMI's hyperspectral capabilities used to derive cloud pressures. The latter has changed how we think about the effects of clouds on total ozone retrievals. We will discuss the evolution of the operational V8.5 algorithm and provide an overview and motivation for V9. After reviewing results and developments of the past decade, we finally highlight how ozone observations from EOS Aura are playing an important role in new ozone mapping missions.

  16. How Tom Moon's research highlighted the question of glucose tolerance in carnivorous fish.

    Science.gov (United States)

    Polakof, S; Panserat, S

    2016-09-01

    Fifteen years ago, Tom Moon wrote a review on this journal in order to propose some explanations to the exacerbated glycaemic response after a glucose load or a carbohydrate meal intake observed in fish, the so-called intolerance to glucose. Before, but in most of cases after this paper, several laboratories worldwide started to make important efforts in order to better understand this strange phenotype observed in fish and that so far seemed to belong to diabetic humans only. Tom had been worked on fish metabolism for at least 30years when he proposed that mini-review and the paths opened by him in 2001 were followed by tens of fish researchers, making this paper a breaking point on the field. Fifteen years later, we propose not only to have a look to the answers given to the questions rose in that paper, but also to summarize how his career over all these years impacted the domain of glucose metabolism in fish. In the review, we will show how Tom Moon analysed at different levels (from genes up to the whole organism), using distinct experimental tools (cells, hormone or glucose injection, pumps, drugs) the questions of glucose metabolism, tolerance and nutrition in fish species. Copyright © 2015 Elsevier Inc. All rights reserved.

  17. Reflexión Tomista: Santo Tomás de Aquino y la Psicología

    Directory of Open Access Journals (Sweden)

    Mauricio Echeverría Gálvez

    2013-01-01

    Full Text Available Asistimos con entusiasmo al nacimiento de la revista "Summa Psicológica", de la Escuela de Psicología de la Universidad Santo Tomás de Chile. Ya con su nombre esta publicación académica rinde un homenaje a la obra principal de Tomás de Aquino, la Summa Theologiae o Suma Teológica. Pero, más allá del nombre, sería interesante indagar cómo la vasta y honda obra de Santo Tomás puede iluminar hoy nuestras reflexiones en el área de la psicología moderna. Por cierto, la autoridad permanente e indiscutida de Tomás de Aquino es reconocida en los ámbitos más diversos, no sólo dentro del mundo cristiano.[...

  18. Occurrence of ozone anomalies over cloudy areas in TOMS version-7 level-2 data

    Directory of Open Access Journals (Sweden)

    X. Liu

    2003-01-01

    Full Text Available This study investigates anomalous ozone distributions over cloudy areas in Nimbus-7 (N7 and Earth-Probe (EP TOMS version-7 data and analyzes the causes for ozone anomaly formation. A 5°-longitude by 5°-latitude region is defined to contain a Positive Ozone Anomaly (POA or Negative Ozone Anomaly (NOA if the correlation coefficient between total ozone and reflectivity is > 0.5 or -0.5. The average fractions of ozone anomalies among all cloud fields are 31.8 ± 7.7% and 35.8 ± 7.7% in the N7 and EP TOMS data, respectively. Some ozone anomalies are caused by ozone retrieval errors, and others are caused by actual geophysical phenomena. Large cloud-height errors are found in the TOMS version-7 algorithm in comparison to the Temperature Humidity Infrared Radiometer (THIR cloud data. On average, cloud-top pressures are overestimated by ~200 hPa (THIR cloud-top pressure 200 hPa for high-altitude clouds and underestimated by ~150 hPa for low-altitude clouds (THIR cloud-top pressure > 750 hPa. Most tropical NOAs result from negative errors induced by large cloud-height errors, and most tropical POAs are caused by positive errors due to intra-cloud ozone absorption enhancement. However, positive and negative errors offset each other, reducing the ozone anomaly occurrence in TOMS data. Large ozone/reflectivity slopes for mid-latitude POAs show seasonal variation consistent with total ozone fluctuation, indicating that they result mainly from synoptic and planetary wave disturbances. POAs with an occurrence fraction of 30--60% occur in regions of marine stratocumulus off the west coast of South Africa and off the west coast of South America. Both fractions and ozone/reflectivity slopes of these POAs show seasonal variations consistent with that in the tropospheric ozone. About half the ozone/reflectivity slope can be explained by ozone retrieval errors over clear and cloudy areas. The remaining slope may result from there being more ozone production

  19. Investigations of Desert Dust and Smoke in the North Atlantic in Support of the TOMS Instrument

    Science.gov (United States)

    Toon, Owen B.

    2005-01-01

    During the initial period of the work we concentrated on Saharan dust storms and published a sequence of papers (Colarco et a1 2002,2003a,b, Toon, 2004). The U.S. Air Force liked the dust model so well that they appropriated it for operational dust storm forecasting (Barnum et al., 2004). The Air Force has used it for about 5 yrs in the Middle East where dust storms cause significant operational problems. The student working on this project, Peter Colarco, has graduated and is now a civil servant at Goddard where he continues to interact with the TOMS team. This work helped constrain the optical properties of dust at TOMS wavelengths, which is useful for climate simulations and for TOMS retrievals of dust properties such as optical depth. We also used TOMS data to constrain the sources of dust in Africa and the Middle East, to determine the actual paths taken by Saharan dust storms, to learn more about the mechanics of variations in the optical depths, and to learn more about the mechanisms controlling the altitudes of the dust. During the last two years we have been working on smoke from fires. Black carbon aerosols are one of the leading factors in radiative forcing. The US Climate Change Science Program calls this area out for specific study. It has been suggested by Jim Hansen, and Mark Jacobsen among others, that by controlling emissions of black carbon we might reduce greenhouse radiative forcing in a relatively painless manner. However, we need a greatly improved understanding of the amount of black carbon in the atmosphere, where it is located, where it comes from, how it is mixed with other particles, what its actual optical properties are, and how it evolves. In order to learn about these issues we are using a numerical model of smoke. We have applied this model to the SAFARI field program data, and used the TOMS satellite observations in that period (Sept. 2000). Our goal is to constrain source function estimates for black carbon, and smoke optical

  20. Effect of phosphate treatments on microbiological, physicochemical changes of spent hen muscle marinated with Tom Yum paste during chilled storage.

    Science.gov (United States)

    Wongwiwat, Pirinya; Wattanachant, Saowakon; Siripongvutikorn, Sunisa

    2010-06-01

    This research aimed to study the effect of phosphate on quality of ready-to-cook spent hen muscle marinated with Tom Yum paste, a famous Thai food made from chilli, lime leaves and garcinia (pH 2.5-2.9). The effects of phosphate treatments (phosphate types, soaking time, and phosphate concentration) on physical characteristics of spent hen muscle in high acid condition were investigated. Quality changes of muscles pretreated with or without phosphate and marinated with Tom Yum paste were determined during storage at 4 degrees C for 30 days. The acidified muscle pretreated with 40 g L(-1) sodium tripolyphosphate for 10 h had the highest marinade absorption, and the lowest cooking loss and shear force among all treatment samples. Microstructures of acidified muscle pretreated with and without sodium tripolyphosphate showed significant swelling with larger fibre diameter. Phosphate pretreatment had no influence on cooking loss, shear force and thiobarbituric acid reactive substance values of Tom Yum marinated muscle during storage. Tom Yum marination with phosphate pretreatment caused a higher increase in psychrophilic bacteria compared to that of marinating without phosphate. Phosphate pretreatment could not improve the physical quality of Tom-Yum marinated spent hen muscle and affected the antimicrobial property of Tom-Yum marinade, resulting in a reduction of shelf-life of the marinated muscle from 30 days to 20 days. Copyright (c) 2010 Society of Chemical Industry.

  1. Investigating the genetic basis of theory of mind (ToM: the role of catechol-O-methyltransferase (COMT gene polymorphisms.

    Directory of Open Access Journals (Sweden)

    Haiwei Xia

    Full Text Available The ability to deduce other persons' mental states and emotions which has been termed 'theory of mind (ToM' is highly heritable. First molecular genetic studies focused on some dopamine-related genes, while the genetic basis underlying different components of ToM (affective ToM and cognitive ToM remain unknown. The current study tested 7 candidate polymorphisms (rs4680, rs4633, rs2020917, rs2239393, rs737865, rs174699 and rs59938883 on the catechol-O-methyltransferase (COMT gene. We investigated how these polymorphisms relate to different components of ToM. 101 adults participated in our study; all were genetically unrelated, non-clinical and healthy Chinese subjects. Different ToM tasks were applied to detect their theory of mind ability. The results showed that the COMT gene rs2020917 and rs737865 SNPs were associated with cognitive ToM performance, while the COMT gene rs5993883 SNP was related to affective ToM, in which a significant gender-genotype interaction was found (p = 0.039. Our results highlighted the contribution of DA-related COMT gene on ToM performance. Moreover, we found out that the different SNP at the same gene relates to the discriminative aspect of ToM. Our research provides some preliminary evidence to the genetic basis of theory of mind which still awaits further studies.

  2. Investigating the genetic basis of theory of mind (ToM): the role of catechol-O-methyltransferase (COMT) gene polymorphisms.

    Science.gov (United States)

    Xia, Haiwei; Wu, Nan; Su, Yanjie

    2012-01-01

    The ability to deduce other persons' mental states and emotions which has been termed 'theory of mind (ToM)' is highly heritable. First molecular genetic studies focused on some dopamine-related genes, while the genetic basis underlying different components of ToM (affective ToM and cognitive ToM) remain unknown. The current study tested 7 candidate polymorphisms (rs4680, rs4633, rs2020917, rs2239393, rs737865, rs174699 and rs59938883) on the catechol-O-methyltransferase (COMT) gene. We investigated how these polymorphisms relate to different components of ToM. 101 adults participated in our study; all were genetically unrelated, non-clinical and healthy Chinese subjects. Different ToM tasks were applied to detect their theory of mind ability. The results showed that the COMT gene rs2020917 and rs737865 SNPs were associated with cognitive ToM performance, while the COMT gene rs5993883 SNP was related to affective ToM, in which a significant gender-genotype interaction was found (p = 0.039). Our results highlighted the contribution of DA-related COMT gene on ToM performance. Moreover, we found out that the different SNP at the same gene relates to the discriminative aspect of ToM. Our research provides some preliminary evidence to the genetic basis of theory of mind which still awaits further studies.

  3. Tom1L1在细胞信号转导及受体内吞中的研究进展%Progresses and Perspectives on the Role of Tom1L1 in Signal Transduction and Endocytosis Pathways

    Institute of Scientific and Technical Information of China (English)

    李娜; 刘宁生

    2014-01-01

    Tom1L1(Tom1 like 1)参与并调节细胞信号转导及受体运输通路.在不同细胞中Tom1L1对信号转导具有不同的调节作用.Tom1L1-CHC(clathrin heavy chain)复合物减少Src蛋白在小窝(caveolae)处富集,从而阻碍Src蛋白与血小板衍生因子(platelet derived growth factor,PDGF)受体的结合,抑制PDGF受体介导的有丝分裂和转化信号传导.活化的表皮生长因子受体(epidermal growth factor receptor,EGFR)通过Src家族蛋白激酶(src family kinase,SFK)磷酸化Tom1L1,磷酸化的Tom1L1通过Grb2和Shc的桥梁作用与EGFR结合,介导EGFR的内吞进程.Tom1L1和Hrs(hepatocyte growth factor regulated tyrosine kinase substrate)、TSG101(tumor susceptibility gene 101)的相互作用表明,它也可能参与了泛素化蛋白分选入多泡体的过程.该文就其在细胞信号转导通路及受体内吞/分选过程的作用作一综述.

  4. Tom Lehman

    Institute of Scientific and Technical Information of China (English)

    2006-01-01

    @@ 最近十年是你打得最棒的时期.如果你能胜任莱德杯球手,那么,你是否能同时担当起队长一职? 我希望我的队伍中有最优秀的12名球手,就是如此简单.如果我打得非常好,并且是这12名球手中最棒的,那么,我不参加就会对这支队伍造成一定的损害.

  5. La Platica de Fray Domingo de Santo Tomás (1560

    Directory of Open Access Journals (Sweden)

    2001-01-01

    Full Text Available La Platica adressée à tous les Indiens et la formule de la Confession Générale sont les deux seuls témoignages du prêche prétridentin en quechua qui survivent jusqu'à nos jours et ceci grâce à leur incorporation comme échantillons de la langue générale dans la grammaire et le Lexicon composés par Domingo de Santo Tomás et publiés à Valladolid en 1560. Dans cet article, nous étudions la variante de la Langue Générale, véhicule de la Platica, et le lexique religieux élaboré par les premiers missionnaires afin d'expliquer la foi chrétienne aux Indiens. La version normalisée du texte quechua est suivie d’une traduction française annotée. Des annexes reproduisent le texte quechua original avec les gloses espagnoles établies par Santo Tomás, le document espagnol qui a servi de modèle à l'élaboration du texte quechua et la transcription de la Confession Générale, sa reformulation en quechua normalisé et sa traduction française. LA PLATICA DE FRAY DOMINGO DE SANTO TOMÁS (1560 La Platica para todos los Indios y la fórmula de la confesión general son los únicos dos testimonios de la prédica pretridentina en quechua que se han conservado hasta el día de hoy y ello debido a su incorporación como muestras de la lengua general en la gramática y lexicón compuestos por Domingo de Santo Tomás y publicados en Valladolid en 1560. En este artículo estudiamos la variante de la lengua general utilizada en la Platica y el léxico religioso elaborado por los primeros misioneros para explicar la fe cristiana a los indios. Una traducción francesa comentada sigue a la versión normalizada del texto quechua. Los anexos reproducen el texto quechua original con las glosas castellanas establecidas por Santo Tomás, el documento en castellano que sirvió de modelo para la elaboración del texto quechua y la transcripción de la confesión general, sa reformulación en quechua normalizado y su traducción al francés. THE PLATICA

  6. Ratio superior, ratio inferior y el agustinismo de Tomás de Aquino

    Directory of Open Access Journals (Sweden)

    Moya Cañas, Patricia

    2013-12-01

    Full Text Available This article discusses Aquinas’ reception of the Augustinian distinction between ratio inferior and superior. Though not a central aspect of Aquinas’ thought, it is a signifi cant pointer to the presence of Augustinian patterns of thought in a non-theological part of his work. After a general survey of the presence of this distinction in the opera omnia of Aquinas, his use of this topic in some specific instances is discussed: the distinction between contemplative and active life, the division of human faculties, and the moral problem of peevish delight.El artículo discute la recepción que hace Tomás de Aquino de la distinción agustiniana entre razón superior e inferior. Si bien no se trata de uno de los tópicos centrales de la doctrina tomasiana, es un elemento significativo a la hora de considerar dentro de la obra de Tomás la presencia de patrones agustinianos de pensamiento que no sean primordialmente teológicos. Tras discutir de modo general la presencia de esta distinción en la obra del aquinate, y los estudios previos sobre este binomio, se procede a discutir su uso por parte de Tomás de Aquino ante tres problemas específicos: la distinción entre géneros de vida, la división de las facultades humanas, y el problema moral de la delectación morosa.

  7. TOMS measurement of the sulfur dioxide emitted during the 1985 Nevado del Ruiz eruptions

    Science.gov (United States)

    Krueger, Arlin J.; Walter, Louis S.; Schnetzler, Charles C.; Doiron, Scott D.

    1990-07-01

    The eruptions of Nevado del Ruiz in 1985 were unusually rich in sulfur dioxide. These eruptions were observed with the Nimbus 7 Total Ozone Mapping Spectrometer (TOMS) which can quantitatively map volcanic sulfur dioxide plumes on a global scale. A small eruption, originally believed to be of phreatic origin, took place on September 11, 1985. However, substantial amounts of sulfur dioxide from this eruption were detected with TOMS on the following day. The total mass of SO 2, approximately 9 ± 3 × 10 4 metric tons, was deposited in two clouds, one in the upper troposphere, the other possibly at 15 km near the stratosphere. The devastating November 13 eruptions were first observed with TOMS at 1150 EST on November 14. Large amounts of sulfur dioxide were found in an arc extending 1100 km from south of Ruiz northeastward to the Gulf of Venezuela and as an isolated cloud centered at 7°N on the Colombia-Venezuela border. On November 15 the plume extended over 2700 km from the Pacific Ocean off the Colombia coast to Barbados, while the isolated mass was located over the Brazil-Guyana border, approximately 1600 km due east of the volcano. Based on wind data from Panama, most of the sulfur dioxide was located at 10-16 km in the troposphere and a small amount was quite likely deposited in the stratosphere at an altitude above 24 km. The total mass of sulfur dioxide in the eruption clouds was approximately 6.6 ± 1.9 × 10 5 metric tons on November 14. When combined with quiescent sulfur dioxide emissions during this period, the ratio of sulfur dioxide to erupted magma from Ruiz was an order of magnitude greater than in the 1982 eruption of El Chichon or the 1980 eruption of Mount St. Helens.

  8. Cross Calibration of TOMS, SBUV/2 and SCIAMACHY Radiances from Ground Observations

    Science.gov (United States)

    Hilsenrath, Ernest; Bhartia, P. K.; Bojkov, B.; Kowaleski, M.; Labow, G.; Ahmad, Z.

    2002-01-01

    We have shown that validation of radiances is a very effective means for correcting absolute accuracy and long term drifts of backscatter type satellite measurements. This method by-passes the algorithms used for both satellite and ground based measurements which are normally used to validate and correct the satellite data. A new method for satellite validation is planned which will compliment measurements from the existing ground-based networks. This method will employ very accurate comparisons between ground based zenith sky radiances and satellite nadir radiances. These comparisons will rely heavily on the experience derived from the Shuttle SBUV (SSBUV) program which provided a reference standard of radiance measurements for SBUV/2, TOMS, and GOME. This new measurement program, called 'Skyrad', employs two well established capabilities at the Goddard Space Flight Center, 1) the SSBUV calibration facilities and 2) the radiative transfer codes used for the TOMS and SBUV/2 algorithms and their subsequent refinements. Radiative transfer calculations show that ground based zenith sky and satellite nadir backscatter ultraviolet comparisons can be made very accurately under certain viewing conditions. The Skyrad instruments (SSBUV, Brewer spectrophotometers, and possibly others) will be calibrated and maintained to a precision of a few tenths of a percent. Skyrad data will then enable long term calibration of upcoming satellite instruments such as QuickTOMS, SBUV/2s and SCIAMACHY with a high degree of precision. This technique can be further employed to monitor the performance of future instruments such as GOMEZ, OMI, and OMPS. Additional information is included in the original extended abstract.

  9. Staging Henry Fielding: The Author-Narrator in Tom Jones On Screen

    Directory of Open Access Journals (Sweden)

    Eli Løfaldli

    2017-06-01

    Full Text Available As recent adaptation theory has shown, classic-novel adaptation typically sets issues connected to authorship and literal and figurative ownership into play. This key feature of such adaptations is also central to the screen versions of Henry Fielding’s Tom Jones (1749. In much of Fielding’s fiction, the narrator, typically understood as an embodiment of Fielding himself, is a particularly prominent presence. The author-narrator in Tom Jones is no exception: not only is his presence strongly felt throughout the novel, but through a variety of means, ‘The History of Tom Jones, A Foundling’ is also distinctly marked as being under his control and ownership. The two adaptations of Fielding’s novel, a 1963 film and a 1997 television series, both retain the figure of the author-narrator, but differ greatly in their handling of this device and its consequent thematic ramifications. Although the 1963 film de-emphasises Henry Fielding’s status as proprietor of the story, the author-narrator as represented in the film’s voiceover commentary is a figure of authority and authorial control. In contrast, the 1997 adaptation emphasises Fielding’s ownership of the narrative and even includes the author-narrator as a character in the series, but this ownership is undermined by the irreverent treatment to which he is consistently subjected. The representations of Henry Fielding in the form of the author-narrator in both adaptations are not only indicative of shifting conceptions of authorship, but also of the important interplay between authorship, ownership and adaptation more generally.

  10. Review roundtable: naked diplomacy: power and statecraft in the digital age by Tom Fletcher

    OpenAIRE

    Kitchen, Nicholas; Wichowski, Alexis; Khatib, Lina; Neumann, Iver B.; Murabit, Alaa; Kelley, Robert

    2016-01-01

    What is the role of the diplomat in the digital age? In Naked Diplomacy: Power and Statecraft in the Digital Age, Tom Fletcher – former British ambassador to Lebanon and the youngest to be appointed in 200 years – draws upon his own experiences to outline a progressive vision of contemporary diplomacy that challenges top-down or one-way models of communication between diplomats and citizens to instead focus on direct engagement through the use of tools such as social media. In this review rou...

  11. Tropical tropospheric ozone derived using Clear-Cloudy Pairs (CCP) of TOMS measurements

    OpenAIRE

    M.J. Newchurch; Sun, D.; Kim, J. H.; Liu, X.

    2003-01-01

    Using TOMS total-ozone measurements over high-altitude cloud locations and nearby paired clear locations, we describe the Clear-Cloudy Pairs (CCP) method for deriving tropical tropospheric ozone. The high-altitude clouds are identified by measured 380 nm reflectivities greater than 80% and Temperature Humidity InfraRed (THIR) measured cloud-top pressures less than 200 hPa. To account for locations without high-altitude clouds, we apply a zonal sine fitting to the stratospheric ozone deri...

  12. Hunting and conservation of forest pigeons in São Tomé (West Africa)

    OpenAIRE

    Carvalho, Mariana Bastos

    2015-01-01

    Doutoramento em Biologia - Instituto Superior de Agronomia On the island of São Tomé, four endemic species of fruit pigeons are hunted as food and/or as an economic resource. This thesis intended to collect and analyze the baseline data required for the management of pigeons, which take into account their importance as a resource but also their overall conservation value. For this, I used a combination of biological and social sampling methods. The results show that harvest of endemic pige...

  13. An Analysis of the Conversational Implicature in The Adventures of Tom Sawyer

    Institute of Scientific and Technical Information of China (English)

    夏增强

    2009-01-01

    Mark Twain is one of the greatest writers in the world. His works are full of humor and satire with vivid conversations and brilliant and trenchant portrayals of those characters. This paper takes his classic The Adventures of Tom Sawyer as an example to analyze the conversational implicature from the perspective of Herbert Paul Grice's famous Cooperative Principle. Through the analysis, we can see that linguistic study can help us to study literary works deeply and it is necessary for us to study the conversational implicature systematically.

  14. Reinterpreting funerals and pastoral care: a pastoral theology response to Tom Long's Accompany Them with Singing.

    Science.gov (United States)

    Fowler, Gene

    2012-03-01

    This article addresses Tom Long's (2009) criticism that a traditional pastoral care approach to funerals is responsible for significant distortions in contemporary Christian funeral practices in the United States. The article will show that his criticism should be affirmed but that his solution for a contemporary understanding of pastoral care and funerals is not adequate. A critique and reinterpretation of pastoral care and funerals will show that Long's reform of Christian funerals needs to incorporate a contemporary understanding of caring for the bereaved in funerals.

  15. Averroes y Tomás de Aquino sobre el concepto de ciencia natural

    OpenAIRE

    Lértora Mendoza, Celina Ana

    2007-01-01

    Al comienzo del libro I de la Physica, Aristóteles plantea la pregunta por la materia y el sujeto de la ciencia natural. Esta cuestión se refiere al concepto de la ciencia cuya indagación inicia. La ciencia natural (philosophia naturalis) ha sido en lo sucesivo objeto de indagaciones específicas, sobre todo en función del comentario al original aristotélico. Averroes1 dedica al tema un conciso y a la vez comprehensivo Proemio. Tomás de Aquino,2 en cambio, y al contrario de otros casos, omite ...

  16. Instituciones microfinancieras y cajas de ahorro en Santo Tomás Hueyotlipan, Puebla

    OpenAIRE

    2014-01-01

    La exigua presencia de los intermediarios financieros formales en los municipios rurales mexicanos impulsa el uso de tandas y solicitud de dinero a prestamistas, familiares o amigos. Las cajas de ahorro constituyen una alternativa a estos métodos tradicionales y aprovechan el capital social comunitario. Esta investigación, fundamentado en una muestra realizada en el municipio de Santo Tomás Hueyotlipan (Puebla, México), analiza los factores que impulsan la participación en las cajas de ahorro...

  17. La justicia como virtud global en Tomás de Aquino

    OpenAIRE

    Dierksmeier, C. (Claus); Celano, A.

    2014-01-01

    La actual economía globalizada no puede regirse únicamente por restricciones legales. Para evitar sus recurrentes crisis sistémicas no es suficiente una combinación de interés propio y regulación; también se necesitan virtudes y un sentido de responsabilidad corporativa para asegurar el éxito sostenido de la economía global. Sin embargo, ¿qué concepción de virtud debe prevalecer en un mundo plural? La teoría moral de Tomás de Aquino, al vincular de modo perspicaz las ideas de justicia y vi...

  18. 访著名吉他制作师Tom Anderso

    Institute of Scientific and Technical Information of China (English)

    Bird Hey(译)

    2012-01-01

    我无数次的通过新闻或者一些艺术家那里听到Tom Anderson这个名字,看上去Anderson吉他作坊非常的有名。在我写这篇文章之前,我没有弹过任何一把Anderson吉他,甚至连见也没见过。但是象我这样一个器材发烧迷怎么能错失如此良好口碑的乐器?

  19. Systematic Comparison of Brain Imaging Meta-Analyses of ToM with vPT

    OpenAIRE

    Aditi Arora; Matthias Schurz; Josef Perner

    2017-01-01

    In visual perspective taking (vPT) one has to concern oneself with what other people see and how they see it. Since seeing is a mental state, developmental studies have discussed vPT within the domain of “theory of mind (ToM)” but imaging studies have not treated it as such. Based on earlier results from several meta-analyses, we tested for the overlap of visual perspective taking studies with 6 different kinds of ToM studies: false belief, trait judgments, strategic games, social animations,...

  20. In Search of the Truth : Examining the Representation of American Society in Tom Wolfe's Writing

    OpenAIRE

    Skjolden, Cathrine

    2004-01-01

    The main concern in this thesis is an examination of Tom Wolfe s presentation of his views on American society in his writing. I have chosen to examine his works of literary journalism, represented by The Electric Kool-Aid Acid Test and Radical Chic, together with his latest fictional work, A Man in Full. The thesis starts with a discussion of the representation of truth in literature. Wolfe operates with a view of how truth and reality are best presented in literary works which is different ...

  1. Representations of social class and urban poverty in Tom Wolfe's The bonfire of the vanities

    OpenAIRE

    Muhonen, Tomi

    2016-01-01

    Yhdysvaltalaista yhteiskuntaa on sen 1900-luvulla kehittyneestä taloudellisesta valta-asemasta huolimatta jo pitkään vaivannut niin sanottu köyhyyden paradoksi: huono-osaisuuden ja epätasa-arvon ilmeneminen yhdessä maailman rikkaimmista valtioista. Tätä paradoksia on käsitelty toisinaan myös amerikkalaisessa kirjallisuudessa, josta esimerkkinä on Tom Wolfe satiirinen romaani The Bonfire of the Vanities (Turhuuksien rovio, 1987). Tämä tutkielma tarkastelee teoksen kuvausta 1980-luvun New Y...

  2. Empathy, ToM, and self-other differentiation: an fMRI study of internal states.

    Science.gov (United States)

    Reniers, Renate L E P; Völlm, Birgit A; Elliott, Rebecca; Corcoran, Rhiannon

    2014-02-01

    This study used functional magnetic resonance imaging to examine the neural substrates of empathy, Theory of Mind (ToM), and self-other differentiation involved in the adaptive understanding of people's internal states. Three conditions were distinguished in both sad and neutral (no obvious emotion) contexts. The empathy condition involved imagining what another person is feeling while the more cognitively loaded ToM condition involved imagining what would make another person feel better. The self-reference condition required participants to imagine how they would feel in someone else's situation. Areas previously implicated in empathy, ToM, and self-other differentiation were identified within the different conditions, regardless of emotional context. Specifically, the frontal and temporal poles responded more strongly for ToM than for empathy. The self-reference condition was associated with stronger dorsolateral prefrontal response than the empathy condition, while the reverse comparison revealed a stronger role for right frontal pole. Activations in frontal pole and orbitofrontal cortex were shared between the three conditions. Contrasts of parameter estimates demonstrated modulation by emotional context. The findings of common and differential patterns of responding observed in prefrontal and temporal regions suggest that within the social cognition network empathy, ToM and self-other differentiation have distinct roles that are responsive to context.

  3. Thermoelectric Oxide Modules (TOMs for the Direct Conversion of Simulated Solar Radiation into Electrical Energy

    Directory of Open Access Journals (Sweden)

    Petr Tomeš

    2010-04-01

    Full Text Available The direct conversion of concentrated high temperature solar heat into electrical energy was demonstrated with a series of four–leg thermoelectric oxide modules (TOM. These temperature stable modules were not yet optimized for high efficiency conversion, but served as proof-of-principle for high temperature conversion. They were constructed by connecting two p- (La1.98Sr0.02CuO4 and two n-type (CaMn0.98Nb0.02O3 thermoelements electrically in series and thermally in parallel. The temperature gradient ΔT was applied by a High–Flux Solar Simulator source (HFSS which generates a spectrum similar to solar radiation. The influence of the graphite layer coated on the hot side of the Al2O3 substrate compared to the uncoated surface on ΔT, Pmax and η was studied in detail. The measurements show an almost linear temperature profile along the thermoelectric legs. The maximum output power of 88.8 mW was reached for a TOM with leg length of 5 mm at ΔT = 622 K. The highest conversion efficiency η was found for a heat flux of 4–8 W cm-2 and the dependence of η on the leg length was investigated.

  4. The Effect of New Ozone Cross Sections Applied to SBUV and TOMS Retrievals

    Science.gov (United States)

    McPeters, Richard D.; Labow, Gordon J.

    2010-01-01

    The ozone cross sections as measured by Bass and Paur have been used for processing of SBUV and TOMS data since 1986. While these cross sections were a big improvement over those previously available, there were known minor problems with accuracy for wavelengths longward of 330 nm and with the temperature dependance. Today's requirements to separate stratospheric ozone from tropospheric ozone and for the derivation of minor species such as BrO and N02 place stringent new requirements on the accuracy needed. The ozone cross section measurements of Brion, Daumont, and Malicet (BDM) are being considered for use in UV-based ozone retrievals. They have much better resolution, an extended wavelength range, and a more consistent temperature dependance. Tests show that BDM retrievals exhibit lower retrieval residuals in the satellite data; i.e., they explain our measured atmospheric radiances more accurately. Total column ozone retrieved by the TOMS instruments is about 1.5% higher than before. Ozone profiles retrieved from SBUV using the new cross sections are lower in the upper stratosphere and higher in the lower stratosphere and troposphere.

  5. Estimation of surface UV levels based on Meteor-3/TOMS ozone data

    Energy Technology Data Exchange (ETDEWEB)

    Borisov, Y.A. [Central Aerological Observatory, Moscow (Russian Federation); Geogdzhaev, I.V. [Moscow Inst. of Physics and Technology, Moscow (Russian Federation); Khattatov, V.U. [Central Aerological Observatory, Moscow (Russian Federation)

    1995-12-31

    The major consequence of ozone layer depletion for the environment is an increase of harmful ultraviolet (UV) radiation on the Earth surface and in the upper ocean. This implies the importance of environmental UV monitoring. Since the direct global monitoring is not currently possible, indirect estimations of surface UV levels may be used based on satellite ozone data (Madronich, S. 1992). Total Ozone Mapping Spectrometer (TOMS) on board the METEOR-3 satellite provided regular set of data for such estimates. During the time of its operation (August, 1991 - December, 1994) the instrument registered several ozone hole events over Antarctica, when ozone levels dropped by as much as 60 % from their unperturbed values. Probably even more alarming ozone depletions were observed over highly populated regions of middle latitudes of northern hemisphere. Radiative transfer modeling was used to convert METEOR-3/TOMS daily ozone values into regional and global maps of biologically active UV. Calculations demonstrate the effect on surface UV levels produced by ozone hole over Antarctica and ozone depletions over the territory of Russia (March, 1994). UV contour lines deviate from the normal appearance which is determined by growing southward solar elevation. UV contour lines are almost perpendicular to the ozone ones in the ozone depletions areas. The 30 % ozone depletion, over Siberia caused more than 30 % increase in noontime erythemal UV levels, which is equivalent to 10-15 degrees southward latitude displacement. Higher UV radiation increases were found in ozone hole over South America (October 1992) equivalent to about 20 degrees southward displacement

  6. Secret Guilt of an Artist: The Real Inspector Hound and Tom Stoppard’s Political Voice

    Directory of Open Access Journals (Sweden)

    Kevin Drzakowski

    2015-12-01

    Full Text Available Tom Stoppard once famously proclaimed his guilt that art is unimportant. The character Moon from Stoppard’s early farce The Real Inspector Hound presents surprising evidence that Stoppard’s view of art in his early years as a playwright may have been more complex than he let on. The circumstances behind Moon’s journey into the very art he criticizes are not unlike Tom Stoppard’s foray into politically conscious drama. Moon desperately wants the thriller he is reviewing to mean more than it really does. His wish becomes a reality when a third party, Puckeridge, forcibly pulls Moon into the fantasy. Like Moon, Stoppard had a fantasy, a dream-world in which art has the power to enact social change. Stoppard was unwilling or unable to act on that desire alone, until his own Puckeridge, an artist and dissident named Victor Fainberg, compelled him to act on his dream and merge art with politics.Keywords: Stoppard, The Real Inspector Hound, Fainberg, art, politics

  7. Statecraft and Leadership in Europe: The Case of Tomáš Garrigue Masaryk

    Directory of Open Access Journals (Sweden)

    Tomas Tatinec

    2014-09-01

    Full Text Available Born to Slovaco-German-Czech poor servants, with no burning interest in politics until adult age, who even came to be called the enemy of the nation, Tomáš Masaryk managed to introduce the first Czechoslovak state on the world map in 1918, through tireless advocacy carried out (literally all around the world during the Great War, and the subsequent guidance in the newly formed republic. He was unanimously elected President four times and served in this function for eighteen years (1918-1935. Tomáš Masaryk was not a product of circumstances, but their producer and skillful employer. He showed himself particularly adroit in overcoming the against-all-odds situations, as well as the ‘regular’ crisis ones. Initially isolated, resourceless, and repudiated by his own people, he managed to unite them and to make them join his idea and struggle for a project aiming for common good. Such a CV seems remarkably appropriate for a potential leader in Europe’s most advanced uniting project, the EU (European Union. Considering the 100th anniversary of the beginning of Masaryk’s state-building journey, as well as the current crisis debates in the EU, it seems appropriate to remind ourselves of a leader with a vision, determination, skill, and principles. The EU may need precisely those to stay united.

  8. Thin layer modeling of tom yum herbs in vacuum heat pump dryer.

    Science.gov (United States)

    Artnaseaw, A; Theerakulpisut, S; Benjapiyaporn, C

    2010-04-01

    Thin layer vacuum heat pump drying experiments were conducted to determine drying models for Tom Yum herbs (chili, lemon grass, kaffir lime leaf and galangal slice). The drying experiments were conducted in a vacuum heat pump dryer at a constant drying pressure of 0.2 bars and drying temperatures ranging from 50 °C to 65 °C. The experimental results were fitted to a number of well-known thin layer drying models and it was found, for the range of drying temperature tested, that the Midilli model is the best model for all Tom Yum herbs. To account for the influence of drying temperature, the constants and coefficients of model were formulated as functions of the drying temperature. Statistical tests of agreement between the model and experimental results were performed by determining the coefficient of determination (R²) , reduced chi-square (χ²) and root mean square error (RMSE). It was found that the model is in very good agreement with the experimental results.

  9. Tomé, futuro turístico y renacer industrial

    Directory of Open Access Journals (Sweden)

    Carol Andaluz Sandoval

    2015-04-01

    Full Text Available La ciudad de Tomé, ubicada en la ribera N.E. de la bahía de Talcahuano, distante a sólo 32 kilómetros al norte del Gran Concepción, se ha desarrollado económica y territorialmente por los diferentes aconteceres que le ha correspondido presenciar durante la historia. Es así como encontramos vestigios de la grandeza de su apogeo pesquero, portuario, molinero, vitivinícola y textil, tanto en el ordenamiento de su trama urbana como en obras arquitectónicas que muestran un claro reflejo de las inmigraciones extranjeras que se vieron atraídas por esta próspera ciudad, que nació como caleta de pescadores y se transformó en un centro industrial de gran importancia nacional. Tal fue su significancia dentro de las zonas costeras del país que en el año 1858, el Congreso Nacional declaró a Tomé Puerto Mayor, lo que se tradujo en un aumento importante de la población, la industria y las actividades que esto conllevaba.

  10. Optimization of factors affecting Agrobacterium-mediated transformation of Micro-Tom tomatoes.

    Science.gov (United States)

    Guo, M; Zhang, Y L; Meng, Z J; Jiang, J

    2012-03-16

    Micro-Tom is the smallest known variety of tomatoes. An orthogonal experimental design L(16) (4(5)) was used to optimize Agrobacterium-mediated transformation of cotyledon explants of Lycopersicon esculentum cv. Micro-Tom. Four parameters were investigated to determine their effect on transformation frequency: the concentration of bacterial suspension, time of dip in bacterial suspension, co-cultivation time, and concentration of carbenicillin. We also examined the effect of these parameters on contamination rate, necrosis rate, mortality, cut-surface browning rate, and undamaged explant rate. Both the bacterial and carbenicillin concentrations had a significant influence on the rate of infected explants. The time of co-cultivation also had a significant influence on the transformation parameters. The optimal transformation protocol consisted of an Agrobacterium suspension of 0.5 × 10(8) cells/mL (OD(600) = 0.5) and an infection time of 5 min, one day of co-cultivation and 500 mg/L carbenicillin. Under these conditions, the transformation efficiency of the shoots reached 5.1%; the mean transformation frequency was 3.9% (N = 838).

  11. Lope y Boccalini: Tres sonetos de Tomé de Burguillos

    Directory of Open Access Journals (Sweden)

    Arellano, Ignacio

    2012-12-01

    Full Text Available The article analyzes three sonnets of Lope against Traiano Boccalini included in the Rhymes of Tomé de Burguillos, showing the need to compare the Lope´s text with the italian original version of Ragguagli di Parnaso, not with spanish translation of Perez de Sousa, because in this translation are deleted essential passages to understand the game of wit of Lope. These three sonnets are a good example of the complexity of this exercise of conceptism in Lope, whose poetry can not be described as plain, simple and clear: it is a difficult poetry full of games, intertextual allusions and references that should be clarified applying the type of appropiate reading.Se analizan tres sonetos de Lope contra el italiano Traiano Boccalini, incluidos en las Rimas de Tomé de Burguillos, mostrando la necesidad de comparar el texto de Lope con el de los Ragguagli di Parnaso, en su versión original italiana, y no en la traducción de Perez de Sousa, que elimina pasajes necesarios para entender los juegos de Lope. Estos tres sonetos son buena muestra de la complejidad que puede tener este ejercicio de agudeza de Lope, cuya poesía no se puede calificar sin más de llana, sencilla o clara: es una poesía conceptista llena de juegos, alusiones y referencias intertextuales que deben ser aclaradas si se quiere aplicar a estos poemas el tipo de lectura que exigen.

  12. Polypeptide Translocation Through the Mitochondrial TOM Channel: Temperature-Dependent Rates at the Single-Molecule Level.

    Science.gov (United States)

    Mahendran, Kozhinjampara R; Lamichhane, Usha; Romero-Ruiz, Mercedes; Nussberger, Stephan; Winterhalter, Mathias

    2013-01-03

    The TOM protein complex facilitates the transfer of nearly all mitochondrial preproteins across outer mitochondrial membranes. Here we characterized the effect of temperature on facilitated translocation of a mitochondrial presequence peptide pF1β. Ion current fluctuations analysis through single TOM channels revealed thermodynamic and kinetic parameters of substrate binding and allowed determining the energy profile of peptide translocation. The activation energy for the on-rate and off-rate of the presequence peptide into the TOM complex was symmetric with respect to the electric field and estimated to be about 15 and 22 kT per peptide. These values are above that expected for free diffusion of ions in water (6 kT) and reflect the stronger interaction in the channel. Both values are in the range for typical enzyme kinetics and suggest one process without involving large conformational changes within the channel protein.

  13. COMMERCIAL APPLICATION OF TOM OPAL 878L CATALYST FOR OLEFIN DECREASING%TOM OPAL 878L型降烯烃催化剂的工业应用

    Institute of Scientific and Technical Information of China (English)

    徐武清; 叶晓东

    2003-01-01

    介绍了洛阳分公司Ⅰ套催化裂化装置使用TOM OPAL 878L降汽油烯烃催化剂的情况.该剂在占系统催化剂藏量46%时进行的标定结果表明:该剂具有比较明显的降汽油烯烃效果,汽油烯烃体积分数由49.7%降到42%,下降了7.7个百分点,汽油辛烷值没有降低;产品分布得到改善,重油裂化能力强,干气和焦炭选择性好,干气产率降低了0.16个百分点,焦炭产率降低了0.81个百分点,轻质油收率增加了1.58个百分点,轻液体收率增加了2.36个百分点.

  14. Accuracy Assessments and Validation of an Expanded UV Irradiance Database from Satellite Total Ozone Mapping Spectrometer (TOMS)

    Science.gov (United States)

    Krotkov, N. A.; Herman, J.; Fioletov, V.; Seftor, C.; Larko, D.; Vasilkov, A.

    2004-01-01

    The TOMS UV irradiance database (1978 to 2000) has been expanded to include 5 new products (noon irradiance at 305, 310, 324, and 380 nm, and noon erythemal-weighted irradiance), in addition to the existing erythemal daily exposure, which permit direct Comparisons with ground-based measurements from UV spectrometers. Sensitivity studies are conducted to estimate uncertainties of the new TOMS UV irradiance data due to algorithm apriori assumptions. Comparisons with Brewer spectrometers as well as filter radiometers are used to review of the sources of known errors. Inability to distinguish between snow and cloud cover using only TOMS data results in large errors in estimating surface UV using snow climatology. A correction is suggested for the case when the regional snow albedo is known from an independent source. The summer-time positive bias between TOMS UV estimations and Brewer measurements can be seen at all wavelengths. This suggests the difference is not related to ozone absorption effects. We emphasize that uncertainty of boundary layer UV aerosol absorption properties remains a major source of error in modeling UV irradiance in clear sky conditions. Neglecting aerosol absorption by the present TOMS algorithm results in a positive summertime bias in clear-sky UV estimations over many locations. Due to high aerosol variability the bias is strongly site dependent. Data from UV-shadow-band radiometer and well-calibrated CIMEL sun-sky radiometer are used to quantify the bias at NASA/GSFC site in Greenbelt, MD. Recommendations are given to enable potential users to better account for local conditions by combining standard TOMS UV data with ancillary ground measurements.

  15. Necessidade e possibilidade da prova da existência de Deus na filosofia de Tomás de Aquino

    OpenAIRE

    Roberta Crivorncica

    2009-01-01

    A questão da existência de Deus acompanha o desenvolvimento intelectual de Tomás de Aquino e tem papel central em sua Suma de Teologia, na qual o filósofo desenvolve sua resposta através das conhecidas cinco vias para a prova da existência de Deus. O objetivo desta dissertação é percorrer o caminho traçado por Tomás de Aquino para chegar às cinco vias, mostrando a necessidade e a possibilidade da prova da existência de Deus como sujeito da Doutrina Sagrada. The question of the e...

  16. 用标准影响世界--访ASHRAE主席Tom Watson

    Institute of Scientific and Technical Information of China (English)

    韩敏; 李嵩

    2013-01-01

      2013年中国制冷展期间,拥有来自132个国家的约54000名会员的美国采暖、制冷和空调工程师学会ASHRAE主席,Tom Watson参加了由联合国环境规划署(UNEP)、中国制冷空调工业协会(CRAA)联合举办的臭氧气候工业圆桌会议。我们也借助此机会,对Watson进行了采访交流。与平时听Watson演讲不太一样,近距离的接触后,感觉其非常平易近人,与他的交谈也在非常轻松的氛围中展开。

  17. Instituciones microfinancieras y cajas de ahorro en Santo Tomás Hueyotlipan, Puebla

    Directory of Open Access Journals (Sweden)

    Kristiano Raccanello

    2014-01-01

    Full Text Available La exigua presencia de los intermediarios financieros formales en los municipios rurales mexicanos impulsa el uso de tandas y solicitud de dinero a prestamistas, familiares o amigos. Las cajas de ahorro constituyen una alternativa a estos métodos tradicionales y aprovechan el capital social comunitario. Esta investigación, fundamentado en una muestra realizada en el municipio de Santo Tomás Hueyotlipan (Puebla, México, analiza los factores que impulsan la participación en las cajas de ahorro informales y su interacción con otros intermediarios financieros informales. Los resultados del modelo probit indican que la participación responde a la posibilidad de poder ahorrar atrayendo a aquellos individuos que no utilizan tandas, prestamistas o deudas con familiares o amigos.

  18. Profiling of melatonin in the model tomato (Solanum lycopersicum L.) cultivar Micro-Tom.

    Science.gov (United States)

    Okazaki, Masateru; Ezura, Hiroshi

    2009-04-01

    Melatonin exists in a considerable variety of plant species. However, the physiological roles of melatonin in plants are not well understood. In this study, the distribution and accumulation of melatonin during leaf and fruit development were analyzed in Micro-Tom, a model cultivar of tomato (Solanum lycopersicum L.). Melatonin was extracted using an acetone-methanol method and measured by enzyme-linked immunosorbent assay. Melatonin was detected in leaves, stems, roots, flowers, fruits, seedlings and seeds in the range of 1.5-66.6 ng/g fresh weight, with seeds containing the highest concentration of melatonin. In fruits and leaves, melatonin concentrations varied depending on the developmental stage, suggesting that melatonin controls some of the processes involved in plant maturation.

  19. TomTom发布摩托车专用GPS导航机

    Institute of Scientific and Technical Information of China (English)

    2010-01-01

    日前,TomTom发布了摩托车专用(脚踏车也可以用)的GPS导航机,名为“Urban Rider”。该产品使用电阻式屏幕,所以即使戴着手套一样可以使用,逻辑也改成只剩下两个大按钮(比以住更大)的界面,路径规划一样有IQRoutes(但资料分忻改收集机车的),并且增强巷弄间的导航。

  20. Spatial Politics in Tom Stoppard’s Rosencrantz and Guildenstern Are Dead

    Directory of Open Access Journals (Sweden)

    Elham Kazemi

    2017-01-01

    Full Text Available http://dx.doi.org/10.5007/2175-8026.2017v70n1p287 This article examines the notion of spatial politics in Tom Stoppard’s Rosencrantz and Guildenstern Are Dead. The two courtiers enter the politically convulsive world of Hamlet, where no legitimate power structure takes hold of the state. Their regularized political rationality ceases to apply to the world; reality violates the empirical knowledge — emplacements, geographical and spiritual directions, and generally identity — of Rosencrantz and Guildenstern. The previously defined functions of places, or heterotopias (in Foucauldian terms, are in a state of abeyance. Therefore, they are lost in the midst of the unknown sets of spatial relations; any sorts of intentional act evade them; and they die and vanish absurdly in a placeless place.

  1. Reuniones, dispersiones. Notas sobre ideas literarias de Tomás Segovia

    Directory of Open Access Journals (Sweden)

    Juan Pascual Gay

    2014-01-01

    Full Text Available Este artículo quiere dar cuenta de diferentes ideas expuestas por Tomás Segovia a lo largo de su oficio de escritor en ensayos, cuadernos de notas y entrevistas. Segovia no desarrolló un pensamiento unitario y sistemático, sino que, más bien, desarrolla esas ideas en diferentes contextos, textos y pretextos, pero esas ideas acaban por volver siem - pre a un ideario que otorga una cohesión insospechada en su obra. Además, muchas veces, sin decirlo, deja entrever la tradición literaria y cultural a la que se adscribe y que permea su obra entera.

  2. Fray Tomás de Torquemada, iconógrafo y promotor de las artes

    Directory of Open Access Journals (Sweden)

    Caballero Escamilla, Sonia

    2009-03-01

    Full Text Available In this study the author analyses the Inquisitor Torquemada’s role in two Dominican foundations: the monasteries of Santo Tomás in Ávila and Santa Cruz in Segovia. The historical context in which they emerged and their association with inquisitorial activities converted them into ideal supports for a message designed by this Dominican friar for the purpose of conveying the prestige of the Order and the involvement of the Monarchy in the struggle against heretics. He used the arts to convey a propagandistic message, adapting older iconographic formulas to his current needs, aimed at promoting the expulsion of the Jews.

    En este trabajo se analiza la ascendencia del inquisidor Torquemada sobre dos fundaciones, el convento de Santo Tomás de Ávila y el de Santa Cruz de Segovia. El contexto histórico en el que surgen y su vinculación con la actividad inquisitorial las convierte en soportes de un mensaje hábilmente diseñado por el fraile dominico en el que pone de manifiesto el prestigio de la Orden de Santo Domingo y la implicación de la Monarquía en la lucha antiherética. Aprovechando la eficacia propagandística del lenguaje plástico, no dudará en acudir a fórmulas iconográficas del pasado adaptándolas a su momento presente, creando el caldo de cultivo necesario para lograr su objetivo, la expulsión de los judíos.

  3. Modeling the Effects of Connecting Side Channels to the Long Tom River, Oregon

    Science.gov (United States)

    Appleby, C.; McDowell, P. F.

    2015-12-01

    The lower Long Tom River is a heavily managed, highly modified stream in the southwestern Willamette Valley with many opportunities for habitat improvements and river restoration. In the 1940s and 1950s, the US Army Corps of Engineers dramatically altered this river system by constructing the Fern Ridge Dam and three, large drop structures, converting the River from a highly sinuous channel to a straight, channelized stream that is interrupted by these grade control structures, and removed the majority of the riparian vegetation. As a result, juvenile spring Chinook salmon are no longer found in the Watershed and the local population of coastal cutthroat trout face limited aquatic habitat. When the river was channelized, long sections of the historical channel were left abandoned on the floodplain. Reconnecting these historical channels as side channels may improve the quality and quantity of aquatic habitat and could allow fish passage around current barriers. However, such construction may also lead to undesirable threats to infrastructure and farmland. This study uses multiple HEC-RAS models to determine the impact of reconnecting two historical channels to the lower Long Tom River by quantifying the change in area of flood inundation and identifying infrastructure in jeapordy given current and post-restoration conditions for 1.5, 5, 10, and 25-year flood discharges. Bathymetric data from ADCP and RTK-GPS surveys has been combined with LiDAR-derived topographic data to create continuous elevation models. Several types of side channel connections are modeled in order to determine which type of connection will result in both the greatest quantity of accessible habitat and the fewest threats to public and private property. In the future, this study will also consider the change in the quantity of physical salmonid habitat and map the areas prone to sedimentation and erosion using CEASAR and PHABSIM tools.

  4. TOMATOMA Update: Phenotypic and Metabolite Information in the Micro-Tom Mutant Resource.

    Science.gov (United States)

    Shikata, Masahito; Hoshikawa, Ken; Ariizumi, Tohru; Fukuda, Naoya; Yamazaki, Yukiko; Ezura, Hiroshi

    2016-01-01

    TOMATOMA (http://tomatoma.nbrp.jp/) is a tomato mutant database providing visible phenotypic data of tomato mutant lines generated by ethylmethane sulfonate (EMS) treatment or γ-ray irradiation in the genetic background of Micro-Tom, a small and rapidly growing variety. To increase mutation efficiency further, mutagenized M3 seeds were subjected to a second round of EMS treatment; M3M1 populations were generated. These plants were self-pollinated, and 4,952 lines of M3M2 mutagenized seeds were generated. We checked for visible phenotypes in the M3M2 plants, and 618 mutant lines with 1,194 phenotypic categories were identified. In addition to the phenotypic information, we investigated Brix values and carotenoid contents in the fruits of individual mutants. Of 466 samples from 171 mutant lines, Brix values and carotenoid contents were between 3.2% and 11.6% and 6.9 and 37.3 µg g(-1) FW, respectively. This metabolite information concerning the mutant fruits would be useful in breeding programs as well as for the elucidation of metabolic regulation. Researchers are able to browse and search this phenotypic and metabolite information and order seeds of individual mutants via TOMATOMA. Our new Micro-Tom double-mutagenized populations and the metabolic information could provide a valuable genetic toolkit to accelerate tomato research and potential breeding programs. © The Author 2015. Published by Oxford University Press on behalf of Japanese Society of Plant Physiologists. All rights reserved. For permissions, please email: journals.permissions@oup.com.

  5. Construction and modelling of a thermoelectric oxide module (TOM) as a demonstrator - Final report

    Energy Technology Data Exchange (ETDEWEB)

    Tomes, P.; Weidenkaff, A.

    2010-08-15

    The project aims at the development of better thermoelectric materials for the direct conversion of solar heat into electricity. The maximum output power P{sub max} and the efficiency {eta} of the conversion was measured on a series of four-leg thermoelectric oxide modules (TOM). The modules were constructed by combining two p-type (La{sub 1.98}Sr{sub 0.02}CuO{sub 4}) and two n-type (CaMn{sub 0.98}Nb{sub 0.02}O{sub 3}) thermoelements connected electrically in series and thermally in parallel. The temperature gradient {Delta}T was provided by a High-Flux Solar Simulator source (HFSS) which generates a spectrum similar to solar radiation. This project was intended to be a feasibility study for the utilization of high temperature solar heat, which could not previously be demonstrated due to the low temperature stability of conventional materials. The direct conversion was proven by this study. The measurements show an almost linear temperature profile along the thermoelectric legs. However, the maximum output power resulted in 88.8 mW for a TOM with a leg length of 5 mm at {Delta}T = 622 K and has yet to be optimized by improving the converter design and the applied materials. The highest conversion efficiency {eta} was found for a heat flux of 4 to 8 W cm{sup -2}. The dependence of {eta} on the leg length was studied as well as the influence of a graphite coating on the hot Al{sub 2}O{sub 3} surface on {Delta}T, P{sub max} and {eta}. (authors)

  6. From the External to the Internal: Behavior Clarifications Facilitate Theory of Mind (ToM) Development in Chinese Children

    Science.gov (United States)

    Liu, Yanchun; Wang, Yijie; Luo, Rufan; Su, Yanjie

    2016-01-01

    The present study investigated how Chinese children develop theory of mind (ToM) in a language environment with limited mental state talk that is rich in behavior discourse. In Study 1, 60 mothers shared a wordless storybook with their 3-4-year-olds. The children completed two false-belief tasks and the Peabody Picture Vocabulary Test-Revised at…

  7. Profiles in Online Learning: A Series on Leadership--Tom Layton: Judo and the Art of Technology Innovation.

    Science.gov (United States)

    Danielson, Larry

    1998-01-01

    Profiles a high school technology teacher and creator of CyberSchool, a distance learning program of the Eugene (Oregon) School District. Discusses Tom Layton's education, early work experience, establishment of a high school English-as-a-Second-Language (ESL) program, integration of computers into the classroom, reputation as a technology leader,…

  8. Profiles in Online Learning: A Series on Leadership--Tom Layton: Judo and the Art of Technology Innovation.

    Science.gov (United States)

    Danielson, Larry

    1998-01-01

    Profiles a high school technology teacher and creator of CyberSchool, a distance learning program of the Eugene (Oregon) School District. Discusses Tom Layton's education, early work experience, establishment of a high school English-as-a-Second-Language (ESL) program, integration of computers into the classroom, reputation as a technology leader,…

  9. Mida teeb sinu organisatsioon, et olla keskkonnasõbralik? / Liis Elmi, Monika Kuzmina, Kairit Kolskar, Kristina Toms...[jt.

    Index Scriptorium Estoniae

    2008-01-01

    Küsimusele vastavad: BEST-Esonia juhatuse liige Liisi Elmi, Rahvaliidu Noored juhatuse esimees Monika Kuzmina, Noored Sotsiaaldemokraadid president Kairit Kolskar, AIESEC president Kristina Toms, Eesti Psühholoogiaüliõpilaste Ühenduse juhatuse liige Andres Vegel

  10. U.S. EPA’s Technical Support for the Reich Farm (Toms River, NJ) Superfund Site Remediation

    Science.gov (United States)

    PowerPoint slide file that gives a brief history of the SAN Trimer contamination in Toms River, NJ as well as the EPA's provided technical support, specifically the development and application of the Provisional Peer-Reviewed Toxicity Value (PPRTV) assessment for SAN Trimer.

  11. Language and ToM Development in Autism versus Asperger Syndrome: Contrasting Influences of Syntactic versus Lexical/Semantic Maturity

    Science.gov (United States)

    Paynter, Jessica; Peterson, Candida

    2010-01-01

    Theory of mind (ToM) development by a sample of 63 children aged 5-12 years (24 with Asperger syndrome, 19 with high-functioning autism, and 20 age-matched typical developers) was assessed with a five-task false-belief battery in relation to both lexical (vocabulary) and syntactic (grammar) language skills. Contrary to some previous research, no…

  12. Geoheritage at the Equator: Selected Geosites of São Tomé Island (Cameron Line, Central Africa

    Directory of Open Access Journals (Sweden)

    Maria Helena Henriques

    2015-01-01

    Full Text Available This work presents, for the first time, an overview of the rich geodiversity outcropping in the São Tomé island, one of the two islands that make up the archipelago of São Tomé and Príncipe, the second smallest state of Africa in area. Located at the equator, in the alignment known as the “Cameroon Volcanic Line”, this archipelago represents a privileged area for the comparative study between oceanic and continental alkaline volcanism, and therefore between the subcontinental and suboceanic mantle. Ten geosites of São Tomé island were selected, described and evaluated on the basis of their geoheritage value and using a qualitative system of classification, which integrates both the meaning attributed to the objects by scientific communities and the public understanding of such meanings related to its social use. The selected geosites display different heritage values (documental, scenic, symbolic, iconographic and indicial potentially usable for different purposes, namely scientific and educational, but mostly tourism. Geotourism can play a key role in the promotion of sustainable development in the Democratic Republic of São Tomé and Príncipe, and the geosites here described are likely to ground a geo-itinerary on this “pearl” of the Cameron Line.

  13. Factorial structure of the 'ToM Storybooks': A test evaluating multiple components of Theory of Mind.

    Science.gov (United States)

    Bulgarelli, Daniela; Testa, Silvia; Molina, Paola

    2015-06-01

    This study examined the factorial structure of the Theory of Mind (ToM) Storybooks, a comprehensive 93-item instrument tapping the five components in Wellman's model of ToM (emotion recognition, understanding of desire and beliefs, ability to distinguish between physical and mental entities, and awareness of the link between perception and knowledge). A sample of 681 three- to eight-year-old Italian children was divided into three age groups to assess whether factorial structure varied across different age ranges. Partial credit model analysis was applied to the data, leading to the empirical identification of 23 composite variables aggregating the ToM Storybooks items. Confirmatory factor analysis was then conducted on the composite variables, providing support for the theoretical model. There were partial differences in the specific composite variables making up the dimensions for each of the three age groups. A single test evaluating distinct dimensions of ToM is a valuable resource for clinical practice which may be used to define differential profiles for specific populations. © 2014 The British Psychological Society.

  14. Language and ToM Development in Autism versus Asperger Syndrome: Contrasting Influences of Syntactic versus Lexical/Semantic Maturity

    Science.gov (United States)

    Paynter, Jessica; Peterson, Candida

    2010-01-01

    Theory of mind (ToM) development by a sample of 63 children aged 5-12 years (24 with Asperger syndrome, 19 with high-functioning autism, and 20 age-matched typical developers) was assessed with a five-task false-belief battery in relation to both lexical (vocabulary) and syntactic (grammar) language skills. Contrary to some previous research, no…

  15. Comparisons Between Ground Measurements of Broadband UV Irradiance (300-380 nm) and TOMS UV Estimates at Moscow for 1979-2000

    Science.gov (United States)

    Yurova, Alla Y.; Krotkov, Nicholay A.; Herman, Jay R.; Bhartia, P. K. (Technical Monitor)

    2002-01-01

    We show the comparisons between ground-based measurements of spectrally integrated (300 nm to 380 nm) ultraviolet (UV) irradiance with satellite estimates from the Total Ozone Mapping Spectrometer (TOMS) total ozone and reflectivity data for the whole period of TOMS measurements (1979-2000) over the Meteorological Observatory of Moscow State University (MO MSU), Moscow, Russia. Several aspects of the comparisons are analyzed, including effects of cloudiness, aerosol, and snow cover. Special emphasis is given to the effect of different spatial and temporal averaging of ground-based data when comparing with low-resolution satellite measurements (TOMS footprint area 50-200 sq km). The comparisons in cloudless scenes with different aerosol loading have revealed TOMS irradiance overestimates from +5% to +20%. A-posteriori correction of the TOMS data accounting for boundary layer aerosol absorption (single scattering albedo of 0.92) eliminates the bias for cloud-free conditions. The single scattering albedo was independently verified using CIMEL sun and sky-radiance measurements at MO MSU in September 2001. The mean relative difference between TOMS UV estimates and ground UV measurements mainly lies within 1 10% for both snow-free and snow period with a tendency to TOMS overestimation in snow-free period especially at overcast conditions when the positive bias reaches 15-17%. The analysis of interannual UV variations shows quite similar behavior for both TOMS and ground measurements (correlation coefficient r=0.8). No long-term trend in the annual mean bias was found for both clear-sky and all-sky conditions with snow and without snow. Both TOMS and ground data show positive trend in UV irradiance between 1979 and 2000. The UV trend is attributed to decreases in both cloudiness and aerosol optical thickness during the late 1990's over Moscow region. However, if the analyzed period is extended to include pre-TOMS era (1968-2000 period), no trend in ground UV irradiance is

  16. TOMS and Ground-based Measurements: Long-term Trends, Spatial Variability, Cloud Effects, and Data Quality.

    Science.gov (United States)

    Eide, H. A.; Dahlback, A.; Stamnes, K.; Høyskar, B.; Olsen, R.; Schmidlin, F.; Tsay, S.

    2003-12-01

    Ground-based measurements and TOMS measurements are mutually beneficial to each other. Ground-based measurements of UV radiation and total column ozone amounts are important for the validation of TOMS measurements. For example, it has been shown that TOMS measurements has a tendency to under-estimate ground UV exposure. Some of these effects can perhaps be ascribed to local cloud effects or choice of ozone profiles in the retrieval algorithm. More ground-based measurements are needed to establish the cause of these discrepancies. Recent technology advances have made ground-based measurements of UV doses and ozone column amounts with inexpensive multi-channel filter instruments not only possible, but also an attractive alternative to other more labor-intensive and weather dependent methods. Filter instruments can operate unattended for long periods of time, and it is possible to obtain accurate ozone column amounts even on cloudy days. We present results from extensive comparisons of the performance of several ground-based instruments (the NILU-UV and GUV filter instruments, as well as the Dobson and Brewer instruments) against the EP-TOMS instrument. The data used in the comparisons are from three different sites where we have had the opportunity to operate more than one type of UV instruments for extended periods of time. The sites include the University of Oslo, Norway, the NASA Goddard Space Flight Center facilities at Wallops Island, VA, and Greenbelt, MD and the University of Alaska, Fairbanks (during the TOMS3F campaign). Our results show that ozone column amounts obtained with current filter-type instruments are just as good as those obtained with the Dobson instrument, and might even out-perform the Dobson instrument on cloudy days. The TOMS measurements are shown to exhibit some more variability, but there is on average very good agreement with the ground- based measurements even for high solar zenith angles (SZA). Further more, our comparison shows that

  17. Groundwater–surface-water exchange and the geologic setting of northern Minnesota's lakes, wetlands, and streams—Modern-day relevance of Tom Winter's legacy

    Science.gov (United States)

    Rosenberry, Donald O.; Melchior, Robert C.; Jones, Perry M.; Strietz, Andrew; Barr, Kelton D.; Lee, David R.; Piegat, James J.

    2011-01-01

    Tom Winter spent nearly 50 years conducting research in earth science, and he specialized in the exchange between groundwater and surface water. Tom's highly productive career began in Minnesota. This fi eld trip revisits many of the places where Tom conducted his early research and demonstrates the continuing relevance of that research. Stops and topics include the groundwater infl uence on the record low stage of White Bear Lake, the contribution of groundwater to continually rising water levels in an abandoned open-pit iron mine, hydrogeology of the Shingobee headwaters aquatic ecosystem research site, hydrogeology of Lake Sallie, geology associated with the Pillager water gap, and the hydrogeology of Little Rock Lake.

  18. Averroes y Tomás de Aquino sobre el concepto de ciencia natural

    Directory of Open Access Journals (Sweden)

    Lértora Mendoza, Celina Ana

    2007-01-01

    Full Text Available Al comienzo del libro I de la Physica, Aristóteles plantea la pregunta por la materia y el sujeto de la ciencia natural. Esta cuestión se refiere al concepto de la ciencia cuya indagación inicia. La ciencia natural (philosophia naturalis ha sido en lo sucesivo objeto de indagaciones específicas, sobre todo en función del comentario al original aristotélico. Averroes1 dedica al tema un conciso y a la vez comprehensivo Proemio. Tomás de Aquino,2 en cambio, y al contrario de otros casos, omite un proemio metodológico, si bien el tema en sí se desarrolla al hilo del comentario del texto del Libro I. El objetivo de este trabajo es analizar las aproximaciones y las diferencias entre la lección I del Comentario al Libro I del Aquinate (donde trata el método de la philosophia naturalis y la exégesis de Averroes en su Proemio y la Summa Prima, a fin de establecer las relaciones entre ambos

  19. Dementia and well-being: A conceptual framework based on Tom Kitwood's model of needs.

    Science.gov (United States)

    Kaufmann, Elke G; Engel, Sabine A

    2016-07-01

    The topic of well-being is becoming increasingly significant as a key outcome measure in dementia care. Previous work on personhood of individuals with dementia suggests that their subjective well-being can be described in terms of comfort, inclusion, identity, occupation and attachment The study aimed to examine Tom Kitwood's model of psychological needs and well-being in dementia based on the self-report of individuals with moderate or severe dementia and to differentiate and elaborate this model in the light of the empirical qualitative data. Nineteen inhabitants of a special long-term care unit were interviewed using a semi-structured interview. Data were analysed using content analysis. Thirty components within Kitwood's model have been identified. A conceptual framework of subjective well-being in dementia was developed based on a theoretical background. The study was able to find indications that Kitwood's model has empirical relevance. Nevertheless, it requires to be extended by the domain agency. Furthermore, the study suggests that individuals with dementia are important informants of their subjective well-being.

  20. Sostenibilidad urbana. Tomé: Una propuesta para evaluar los planes reguladores chilenos

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    Carolina Rojas Quezada

    2015-03-01

    Full Text Available Este artículo valora la sostenibilidad en la planificación urbana por medio del diseño de un sistema de indicadores, que surgen de la identificación de los atributos del Planeamiento Urbano Sostenible. Los indicadores se ensayan en el modelo de ocupación del suelo propuesto y establecido en el instrumento de planificación territorial denominado "Plan Regulador Comunal". El estudio se aplica en la localidad de Tomé, ubicada en la VIII Región del Bio Bío de Chile. La obtención de los indicadores de sostenibilidad urbana se desarrolla a partir del uso de las herramientas de Sistemas de Información Geográfica ó SIG. El planeamiento urbano propuesto se evalúa con un sistema de indicadores basados en 3 componentes territoriales que se procesan en la zonficación del suelo urbano propuesto y que son, la distribución de usos y estructura fisica, el consumo de Suelo y la calidad ambiental. El método combina el analisis bibliográfico, con la aplicación de análisis espacial y geoprocesamiento en SIG. Los resultados se aproximan a valorar la sostenibilidad del modelo territorial propuesto.

  1. Tomás de Aquino: filosofia e pedagogia = Thomas Aquinas:philosophy and pedagogy

    Directory of Open Access Journals (Sweden)

    Luiz Jean Lauand

    2012-01-01

    Full Text Available O artigo discute a conexão ente filosofia e educação em Tomás de Aquino. Em sua antropologia filosófica, destacam-se três aspectos de grande atualidade para a educação hoje: a valorização da matéria no ser do homem, a primazia da virtude da prudência entre as virtudes cardeais e a philosophia negativa (e theologia negativa. A intrínseca união entre espírito e matéria, anima forma corporis tem também importantes consequências pedagógicas, tanto para a educação intelectual quanto para a moral. E está na base de seu De prudentia, que pressupõe também sua perspectiva negativa.This article discusses the connection between philosophy and education in Thomas Aquinas. In his Philosophical Anthropology there are three aspects very important for education today: the affirmation of matter as an essential in human being, the primacy of prudentia over the cardinal virtues and his philosophia negativa (and theologia negativa. The intrinsec union spirit-matter, anima forma corporis has important pedagogical consequences, both in intellectual and in moral education. And it is the basis for his Treatise On Prudence, which presupposes his negative perspective too.

  2. Proceso inquisitorial contra el bordador Tomás Pérez

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    Rokiski Lázaro, María Luz

    2002-12-01

    Full Text Available El siglo XVI fue un período muy brillante para el arte del bordado en Cuenca, sin embargo sabemos muy poco sobre sus artífices, de ahí el interés que tiene el proceso inquisitorial de Tomás Pérez pues nos permite conocer a uno de aquellos maestros que con su buen hacer contribuyó a que el bordado, principalmente el religioso, adquiriera gran esplendor en Cuenca. El 17 de agosto de 1571 el clérigo Gonzalo de Cetina, que era descendiente de judíos y en esa fecha residía en El Acebrón (Cuenca, donde desempeñaba su labor como cura párroco, se dirigió al tribunal de la Inquisición de Cuenca solicitando que permitiera a su hermano Isidro de la Muela viajar al Perú, pues quería visitar a un hermano que vivía en Lima, fray Alonso de Cetina, que era agustino....

  3. Polo gastronómico Tomás Jofré

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    Regina G. Schlüter

    2008-01-01

    Full Text Available El turismo gastronómico está adquiriendo cada vez mayor importancia en el mundo, independientemente de si se trata de un país desarrollado o no. En Argentina este tipo de turismo cuenta con una larga tradición, en particular referida al enoturismo que se refleja en la Fiesta Nacional de la Vendimia que se lleva a cabo desde 1936 en la provincia de Mendoza. Hacia fines del siglo XX un plan nacional de turismo hace referencias explícitas a las rutas alimentarias y a partir de allí, desde el sector privado, surgen iniciativas para desarrollar destinos en función de su gastronomía. Una de estas iniciativas se relaciona con la transformación de un pequeño pueblo en un polo gastronómico de gran atracción. En este artículo se presentan los resultados de un estudio que se hizo en el mismo para determinar el perfil de los visitantes y las motivaciones que tienen las personas para desplazarse hacia Tomás Jofré los días domingos.

  4. India e Inghilterra allo specchio. Un ritratto post-imperiale di Tom Stoppard

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    Lucia Esposito

    2011-11-01

    Full Text Available L’ articolo è incentrato su un sofisticato lavoro radiofonico del drammaturgo inglese Tom Stoppard dal titolo In the Native State (1991. In esso l’autore affronta i problemi legati all’etica dell’Impero britannico nei suoi rapporti con la cultura e il popolo indiani sia nel periodo coloniale sia in quello post-coloniale. A tale scopo, il radiodramma mette a confronto, facendole specchiare l’una nell’altra, due ambientazioni differenti, l’India negli anni Trenta e la città di Londra nel 1990. Le questioni trattate, come le secolari occidentalizzazione della mentalità e della cultura indiane da un lato, e indianizzazione della lingua e dei costumi inglesi dall’altro, vengono abilmente traslate dall’autore in termini artistici, visto che gli scambi reciproci tra i due mondi sembrano potersi visualizzare nello stile ibrido di due ritratti eseguiti dal pittore indiano protagonista dell’opera, il quale, nonostante la sua mimicry degli occidentali – per usare un termine caro a Homi Bhabha – o forse proprio grazie ad essa, diventa il mezzo attraverso il quale assistiamo a un fondamentale cambio di prospettiva: dalla visione e rappresentazione eurocentrica dell’Oriente alla riappropriazione di un punto di vista nazionalista indiano che anticipa il successo del movimento che portò il paese all’indipendenza negli anni Quaranta.

  5. Negotiating international bioethics: a response to Tom Beauchamp and Ruth Macklin.

    Science.gov (United States)

    Baker, Robert

    1998-12-01

    Can the bioethical theories that have served American bioethics so well, serve international bioethics as well? In two papers in the previous issue of the Kennedy Institute of Ethics Journal, I contend that the form of principlist fundamentalism endorsed by American bioethicists like Tom Beauchamp and Ruth Macklin will not play on an international stage. Deploying techniques of postmodern scholarship, I argue that principlist fundamentalism justifies neither the condemnation of the Nazi doctors at Nuremberg, nor, as the Report of the Advisory Committee on the Human Radiation Experiments (ACHRE) demonstrates, condemnation of Cold War radiation researchers. Principlist fundamentalism thus appears to be philosophy bankrupt. In this issue of the Journal, Beauchamp and Macklin reject this claim, arguing that I have misread the ACHRE report and misunderstood Nazism. They also argue that the form of post-postmodern negotiated human rights theory that I proffer is adequate only insofar as it is itself really fundamentalist; insofar as I take postmodernism seriously, however, I mire international bioethics in relativism. In this response, I reaffirm my anti-fundamentalism, provide further evidence in support of my reading of the ACHRE report, and defend my post-postmodern version of rights theory. I also develop criteria for a minimally adequate theoretical framework for international bioethics.

  6. Re-processing TOMS UV Measurements to Retrieve SO2 Emissions From Volcanic Eruptions

    Science.gov (United States)

    Fisher, B. L.; Krotkov, N. A.; Bhartia, P. K.; Li, C.; Haffner, D. P.; Leonard, P.; Carn, S. A.; Telling, J. W.

    2015-12-01

    The SO2 Monitoring Group at the NASA Goddard Space Flight Center is producing a new multi-satellite long term data set of volcanic SO2 column amounts and heights (MSVOLSO2L4) as part of the NASA MEaSUREs Program. Here we present re-analysis of the UV measurements (BUV) from the NASA Nimbus 7 Total Ozone Mapping Spectrometer (N7 TOMS: 1978-1993). Ozone is the dominant atmospheric absorber in the BUV spectrum, but volcanic eruptions can produce enough SO2 to be distinguished from ozone background. Quantitative retrieval of volcanic SO2 requires:1) Separation of the O3 and SO2 absorption in BUV radiances;2) Close to zero mean SO2 background;3) RT forward model that accounts for the presence of volcanic ash in the plume; 4) A priori knowledge of the ozone and SO2 vertical profiles.Our iterative retrieval algorithm returns O3 and SO2 column amounts, effective reflectivity and its spectral slope. The retrieval model also generates a 4 x 4 gain matrix for the SO2 free regions that is used to soft calibrate the measured 340 nm BUV radiance. The spectral slope implicitly accounts for the interference of volcanic ash, but more explicit ash treatment is required to better quantify SO2 errors in volcanic plumes heavily loaded with ash. This presentation will discuss the methods used to characterize the error sources and assess the quality of this unique long-term SO2 data set.

  7. La libertad humana como valor primordial en Tomás de Aquino

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    Dietrich Lorenz

    2004-01-01

    Full Text Available Me he propuesto en este artículo acercarme a la relación que existe en Tomás de Aquino entre el concepto de persona, libertad y felicidad, teniendo presente que, en este autor, aquel que es llamado a pensar su felicidad y sus deseos, no es el hombre en abstracto, como se tiende a pensar, sino este hombre (hoc aliquid de frente y en relación a la naturaleza de la cual forma parte, frente a otros hombres con quienes convive, y frente al fin último que lo ayuda a orientarseIn this article, the author attempts to disclose the relationship between the concepts of person, liberty and happiness in Thomas Aquinas thought. To do so, the author emphasizes the point that in Aquinas' work Man is not an abstraction, as it is usually thought, but a real Man who is called to think of his happiness and desires. This man (hoc aliquid is the one who faces and relates to nature, of which he is part of, the one who faces other men he lives with, and the one who faces the ultimate end, which helps him find his orientation

  8. 'for their own purpose of identity': Tom Stannage and Australian Local History

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    David Carment

    2013-12-01

    Full Text Available Tom Stannage made a significant contribution to Australian local history and regularly returned to it throughout his career, frequently speaking and writing about the local past and collaborating with the community organisations that promoted it. In the context of Stannage's perspectives, the work of some other historians and the author's experiences, this article briefly reflects on the state of local history in Australia and the role of local historical societies. The focus is on New South Wales and the Northern Territory, the parts of Australia that the author knows best, but some attention is also given to the rest of the country. The article considers why the work of local historians and historical societies matters in understanding the bigger picture of Australian history. The various attempts to tell the stories of individual communities quite frequently by and for local residents themselves encourage speculation on their contributions to the broader process of historical inquiry. Local history is, as Stannnage strongly believed it ought to be, usually a democratic phenomenon and one that allows a diverse range of approaches. The historical societies that survive and develop do so because they are solidly based in their communities. Perhaps even more crucial, the data of the past that local historical societies have often unearthed and recorded help allow Australians to shape what Stannage so aptly described as a 'history for their own purposes of identity'.

  9. Língua Gestual de São Tomé e Príncipe : retrato dos primeiros gestos

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    Ana Mineiro

    2016-09-01

    Full Text Available This paper aims to portray the genesis of São Tomé and Príncipe Sign Language. At the request of the Government of São Tomé and Principe (Ministry of Education, Culture and Science, Cell Special Education, the Portuguese Catholic University together with the Marquês of Valle Flôr Institute and Hospital CUF Infante Santo collaborated on a common project: to implement a Sign Language for the deaf Santomean. This project, funded by the Calouste Gulbenkian Foundation, was given the name of Without Barriers. The paper is structured in two parts: the first part, which describes, in summary, the main lines of action of the project, the participants enrolled in the project and the methodology used and the second part that analyzes the emergence of the first signs, using sometimes, comparison with other emerging languages.

  10. Gastronomía y turismo en Argentina. Polo gastronómico Tomás Jofré

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    Schlüter, Regina G.

    2008-04-01

    Full Text Available Culinary Tourism in Argentina. The Case of Tomás Jofré. The importance of culinary tourism is growing steadily both in developing and industrialized societies. Argentina has a long tradition regarding this kind of tourism, mainly wine tourism, reflected in the National Wine Festival held since 1936 en the province of Mendoza. By the end of the 20th century culinary tourism was brought into the national tourism plan and it was the start for the private sector to develop own initiatives in order to develop small towns into culinary attractions for visitors. This article presents the results of a study undertaken in order to get acquainted with the visitor profile and motivations for visitors to Tomás Jofré during Sun-days.

  11. Representationen av genus : En semiotisk studie av Tom Fords Gucci kampanj 2003 samt Frida Gianninis Gucci kampanj 2013

    OpenAIRE

    Andréasson, Sara

    2013-01-01

    Title: The representation of gender: A semiotic study of Tom Ford's Gucci campaign 2003 and Frida Gianninis Gucci Campaign 2013. Number of pages: 73 (79 including enclosures) Author: Sara Andréasson Tutor: Anne-Marie Morhed Course: Media and Communication Studies D (2IV091) Period: VT 2013 University: Division of Media and Communication, Department of Informatics and Media, Uppsala University. Purpose/ Aim: The aim of this study was to examine the representation of gender in advertising that ...

  12. Validation of OMI-TOMS and OMI-DOAS total ozone column using five Brewer spectroradiometers at the Iberian peninsula

    Science.gov (United States)

    Antón, M.; López, M.; Vilaplana, J. M.; Kroon, M.; McPeters, R.; Bañón, M.; Serrano, A.

    2009-07-01

    This article focuses on the comparison of the total ozone column data from the Ozone Monitoring Instrument (OMI) flying aboard the NASA EOS-Aura satellite platform with ground-based measurement recorded by Brewer spectroradiometers located at five Spanish remote sensing ground stations between January 2005 and December 2007. The satellite data are derived from two algorithms: OMI Total Ozone Mapping Spectrometer (OMI-TOMS) and OMI Differential Optical Absorption Spectroscopy (OMI-DOAS). The largest relative differences between these OMI total ozone column estimates reach 5% with a significant seasonal dependence. The agreement between OMI ozone data and Brewer measurements is excellent. Total ozone columns from OMI-TOMS are on average a mere 2.0% lower than Brewer data. For OMI-DOAS data the bias is a mere 1.4%. However, the relative difference between OMI-TOMS and Brewer measurements shows a notably lower seasonal dependence and variability than the differences between OMI-DOAS and ground-based data. For both OMI ozone data products these relative differences show significant dependence on the satellite ground pixel solar zenith angle for cloud-free cases as well as for cloudy conditions. However, the OMI ozone data products are shown to reveal opposite behavior with respect to the two antagonistic sky conditions. No significant dependency of the ground-based to satellite-based differences with respect to the satellite cross-track position is seen for either OMI retrieval algorithm.

  13. Statistical interpolation of ozone measurements from satellite data (TOMS, SBUV and SAGE II) using the kriging method

    Energy Technology Data Exchange (ETDEWEB)

    Tranchant, B.J.S.; Vincent, A.P. [Montreal Univ., PQ (Canada). Dept. of Physics; Centre for Research on Computation and its Applications (CERCA), Montreal, PQ (Canada)

    2000-06-01

    This study demonstrates that ordinary kriging in spherical coordinates using experimental semivariograms provides highly usable results, especially near the pole in winter and/or where there could be data missing over large areas. In addition, kriging allows display of the spatial variability of daily ozone measurements at different pressure levels. Three satellite data sets were used: total ozone mapping spectrometer (TOMS) data, solar backscattered ultra violet (SBUV), and the stratospheric aerosol and gas experiment (SAGE II) ozone profiles. Since SBUV is a nadir-viewing instrument, measurements are only taken along the sun-synchronous polar orbits of the satellite. SAGE II is a limb-viewing solar occulation instrument, and measurements have high vertical resolution but poor daily coverage. TOMS has wider coverage with equidistant distribution of data (resolution 1 x 1.25 ) but provides no vertical information. Comparisons of the resulting SBUV-interpolated (column-integrated) ozone field with TOMS data are strongly in agreement, with a global correlation of close to 98%. Comparisons of SBUV-interpolated ozone profiles with daily SAGE II profiles are relatively good, and comparable to those found in the literature. The interpolated ozone layers at different pressure levels are shown. (orig.)

  14. ‘My country’s heart is in the market place’: Tom Stannage interviewed by Peter Read

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    Tiffany Shellam

    2013-12-01

    Full Text Available Tom Stannage was one among many historians in the 1970s uncovering histories of Australia which were to challenge national narratives and community memories. In 1971, Tom returned to Western Australia after writing his PhD in Cambridge with the passion to write urban history and an understanding that in order to do so, he needed an emotional engagement with place. What he had yet to realize was the power of community memories in Western Australia to shape and preserve ideas about their place. As part of his research on the history of Perth, Tom saw how the written histories of Western Australia had been shaped by community mythologies – in particular that of the rural pioneer. He identified the consensus or ‘gentry tradition’ in Western Australian writing. In teasing out histories of conflict, he showed how the gentry tradition of rural pioneer histories silenced those of race and gender relations, convictism and poverty which were found in both rural and urban areas. His versions of history began to unsettle parts of the Perth community who found the ‘pioneer myth’ framed their consensus world-view and whose families were themselves the living links to these ‘pioneers’.

  15. Race Matters… Still. Rezension zu Tom Angotti und Sylvia Morse (Hg. (2016: Zoned Out! Race, Displacement, and City Planning in New York City. New York City: Terreform.

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    Yuca Meubrink

    2017-06-01

    Full Text Available In ihrem Sammelband Zoned Out! identifizieren Tom Angotti und Sylvia Morse zoning als eines der Planungsinstrumente, welches die historischen Muster ethnischer Diskriminierung und Segregation in New York bis heute immer wieder reproduziert hat. [...

  16. TOMS/Nimbus-7 UV Reflectivity Monthly L3 Global 1x1.25 deg Lat/Lon Grid V008

    Data.gov (United States)

    National Aeronautics and Space Administration — This data product contains TOMS/Nimbus-7 UV Reflectivity Monthly L3 Global 1x1.25 deg Lat/Lon Grid Version 8 data in ASCII format. The Total Ozone Mapping...

  17. On the correspondence between surface UV observations and TOMS determinations of surface UV: a potential method for quality evaluating world surface UV observations

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    C. Cornwall

    2003-06-01

    Full Text Available A comparison of erythemally weighted surface UV irradiance observations with similar NASA TOMS surface UV determinations is described. Comparisons are made for two observation periods: the Robertson-Berger (R-B meter period from 1974 to the late 1980s and the current period from 1996 to the present when more sophisticated UVB-1 instruments were used. The more primitive R-B meter observations that comprised the fi rst U.S. UV network are seen to drift downward with respect to those of the TOMS. While the UVB-1 observations did not appear to drift, a substantial bias is noted to exist between the TOMS and the UVB-1 stations collecting observations; the TOMS estimations tend to be higher. A portion of the bias may be attributed to errors in calibration, total ozone, and cosine response of the surface instrumentation. Unaccounted aerosol effects, although not considered to be large in the TOMS estimations, present another source of error. Comparisons are fi rst done for all sky conditions and then for clear sky conditions. The biases typically agree for all sky conditions within the uncertainties of the surface instruments' calibrations, liberally defi ned as ± 5%, implying that the TOMS cloud correction scheme performs reasonably well. Snow cover severely impacts the TOMS observations, giving considerably higher estimations. The biases for clear sky conditions ranged from 15% to 19% with no obvious drifts between the satellite and surface observations. The variation in the biases among stations is within the calibration uncertainties of the instruments, but the absolute bias is unexpectedly large. The standard deviations of the clear sky comparisons among all stations are steady at 4.8% ± 0.7%. A plot of the TOMS/UVB-1 ratio versus TOMS cloud refl ectivity observations is noisy, but qualitatively suggestive of a possible slight increase (~ 5% or greater over the range of clear to overcast skies. The results from these comparisons

  18. Metabolite profile of the tomato dwarf cultivar Micro-Tom and comparative response to saline and nutritional stresses with regard to a commercial cultivar.

    Science.gov (United States)

    Flores, Pilar; Hernández, Virginia; Hellín, Pilar; Fenoll, Jose; Cava, Juana; Mestre, Teresa; Martínez, Vicente

    2016-03-30

    The dwarf tomato variety Micro-Tom has been used as a plant model for studies of plant development. However, its response to environmental and agricultural factors has not been well studied. This work studies the phytochemical content of Micro-Tom tomato and its comparative response to saline and nutritional (N, K and Ca) stresses with regard to a commercial variety. The chromatographic profiles of Micro-Tom were similar to those of the commercial variety and the only differences appear to be the concentration of the components. In Micro-Tom, the concentrations of sugars and organic acids increased by salinity in a lesser extent than in Optima. Moreover, contrary to that observed in the commercial variety, phenolic compounds and vitamin C did not increase by salinity in the dwarf variety. However, both varieties increased similarly the concentrations of carotenoids under saline conditions. Finally, fruit yield and most primary and secondary metabolite concentrations in Micro-Tom were not affected by N, K or Ca limitation. The mutations leading to the dwarf phenotype did not greatly alter the metabolite profiles but studies using Micro-Tom as a plant model should consider the lower capacity for sugars and organic acids under saline conditions and the greater tolerance to nutrient limitation of the dwarf variety. © 2015 Society of Chemical Industry.

  19. Teenage pregnancy - a study in São Tomé and Príncipe.

    Science.gov (United States)

    Carvalho, Fábia; Medeiros, Inês de; Faria, Catarina; Cotu, Djamilla; Will, Endza Paula; Neves, Edgar; Pontes, Teresa

    2017-08-22

    Introduction The increasing number of pregnant teenagers in São Tomé and Príncipe (STP) represents a serious public health issue. The aim of this study was to characterize the population of pregnant adolescents followed in a health facility dedicated to maternal health in STP. Methods A cross-sectional survey was conducted among pregnant teenagers that attended the Mother and Child Protection Center during the first quarter of 2017. The survey contained questions on sociodemographic characteristics, sexual and risk behaviors, family, partners and health support. Results The mean age of the 51 pregnant teenagers included was 16.37 ± 0.8 years. Eight girls reported that they had planned to fall pregnant. Teenagers whose pregnancy was unplanned usually present with a previous family history of adolescent pregnancy. About 59% of girls engaged in sexual activity before 16 years of age with a mean number of sexual partners of 1.84 ± 0.88. In this study, 51% of the girls do not use any contraceptive method, usually because their partner refuses to do so. The preferred contraceptive method are condoms. Information on contraception is given mainly at school. Pregnant girls' first medical consultation was at a mean gestational age of 6 weeks. Abortion was considered by 51% of girls after pregnancy was confirmed. Conclusion Teenage pregnancy imposes health problems for the mother and child and contributes to educational and socioeconomic disadvantages. The collaboration of healthcare providers, teachers and parents is needed to enhance sexual health education. This is the first study in STP on teenage pregnancy; although the sample is small, the authors believe that the results are representative of the general population.

  20. The Former Miss Barstow with every Tom, Dick and Harry in a doll's house

    Directory of Open Access Journals (Sweden)

    Richard Newton

    2015-02-01

    Full Text Available Julie Holledge, panel chairperson and member of the International Ibsen Committee, invited myself along with 3 others to participate in the Inaugural Artists’ Keynote Panel: Applied Ibsen on Four Continents: The Artists’ Intentions. My presentation focused on “The Former Miss Barstow with every Tom, Dick and Harry in a doll’s house.” This was an adaptation of Ibsen’s “A Doll’s House” produced and staged in Los Angeles, California, 1987.  For the XIIIth International Ibsen Conference at the University of Tromsø, Norway, I projected images; a few found on the internet, and many from the production itself, as well as a video clip shown streaming live from YouTube. The article describes the social context of the 80s, analyzes the reinterpretation of Ibsen’s characters, and sets out to explain the symbology of the sets and costumes. I also touch on the differences between this production and Ibsen’s original in four important aspects. These would be the macaroons, the Tarantella, the silk stockings and the end of the play. Finally, I explain my decision to upload this version of “A Doll’s House,’ scene by scene, to my page on YouTube. Having shown films and videos for many years at festivals around the globe, I was looking for a way to step outside that box and reach an international audience just beyond my keyboard. In all of these ways, the goal has been to illuminate the ways in which an artist takes Ibsen’s text and applies it to the specific social context of their time and culture.

  1. Tom Kibble and the early universe as the ultimate high energy experiment

    Science.gov (United States)

    Turok, Neil

    2014-02-01

    Tom Kibble pioneered the idea that there were one or more symmetry breaking phase transitions in the very early universe, at which defects like monopoles, strings and domain walls would have formed. In the context of grand unified theories, or their extensions, this idea remains compelling: observing these defects would be one of the very few ways of directly confirming the theories. In contrast, inflationary theory invoked a strongly supercooled transition driving a period of exponential expansion which would sweep all such defects away. If inflation terminated slowly, quantum vacuum fluctuations would be amplified and stretched to cosmological scales, forming density variations of just the character required to explain the formation of galaxies. The ensuing paradigm has dominated cosmology for the last three decades. However, basic problems in the scenario remain unresolved. Extreme tuning both of the initial conditions and of the physical laws are required. There are many different versions, each with slightly different predictions. Finally, inflation brought with it the theory of a "multiverse" — a universe containing infinite number of different, infinite, universes — while providing no "measure" or means of calculating the probability of observing any one of them. I will discuss an alternative to inflation, in which the big bang was a bounce from a previous contracting epoch. The discovery of the Higgs boson at the LHC has provided new evidence for such a picture by showing that, within the minimal standard model, our current vacuum is metastable. This opens the door to a cyclic universe scenario in which the electroweak Higgs plays a central role.

  2. Fin del mundo, según Tomás de Aquino

    Directory of Open Access Journals (Sweden)

    Patricia Moya Cañas

    2000-01-01

    Full Text Available La actitud de Tomás de Aquino ante la interrogante que suscita el fin del mundo está marcada por un realismo que se dirige más bien a la acción intrahistórica del hombre guiada por las verdades de la Revelación. El análisis de los capítulos 79 y 97 del Libro IV de la Suma Contra Gentiles, orienta en el pensamiento tomasiano y revela la importancia asignada a la unión sustancial alma-cuerpo en el hombre al enfatizar la conveniencia de la resurrección del cuerpo humano al fin de los tiempos. Esta afirmación está en estrecha vinculación con la unidad entre el mundo material y el humano que será mantenida en la consumación de la historia. Así se fundamenta filosóficamente la doctrina cristiana de un antropocentrismo directamente ligado a la Encarnación del Verbo.The position of Thomas Aquinas to the query about the end of the world is marked by a realism which rather points to the intrahistoric action of Man led by the revealed truths. The analysis of the chapters 79 and 97 of the Book IV of the Suma Contra Gentiles, give some orientation onto the Tomistic thought and reveal the importance assigned to the substantial union of boy and soul in man, by emphasising the convenience of the resurrection of the body at the end of the times. This assertion is closely related to the unity between the material and the human world which will remain at the consummation of history. This provides a philosophical support to the Christian doctrine of an anthropocentrism directly linked to the Incarnation of the Verb.

  3. Ecologization of water-land property matters on the territory of the Tom lower course

    Science.gov (United States)

    Popov, V. K.; Kozina, M. V.; Levak, Yu Yu; Shvagrukova, E. V.

    2016-03-01

    In the present paper the water-land property complex is considered as a strategic resource of the city development. The formulated question is expounded through the example of water-land property complex usage on the territory of the Tom lower course for land-use planning and developing the systems of water recourses management and land tenure. Consequences of liquid radioactive waste (LRW) landfilling are investigated in terms of arable farming. Also, forming a water budget of the soils spread on the area of the Tomsk underground water supply cone of depression and its role in the development of agricultural industry are studied. The main aspect of the analysis is the incorporation of social, economic, and ecological requirements for the system of life-supporting branches of municipal economy and social services. As far as the system of land tax payments plays an important role in land property complex management, the common issues and tendencies are specified in the paper. These problems are concerned with the inadequate incorporation of an ecological constituent in the methods of cadastral valuation of lands, as well as the situation of the narrow area of its results usage in the Russian Federation. Natural factors (hydrological, territorial, geological (geomorphologic) territory conditions) are combined by the authors into a special group. These factors should be reflected in the results of cadastral valuation. Also, in order to protect the interests of water consumers, it is offered to establish the Water Consumers Association based on the international experience of such countries as Spain and Uzbekistan.

  4. Strong enhancement of Penning ionization for asymmetric atom pairs in cold Rydberg gases: the Tom and Jerry effect

    KAUST Repository

    Efimov, D K

    2016-05-18

    We consider Penning ionization of Rydberg atom pairs as an Auger-type process induced by the dipole-dipole interaction and employ semiclassical formulae for dipole transitions to calculate the autoionization width as a function of the principal quantum numbers, n d, n i, of both atoms. While for symmetric atom pairs with the well-known increase of the autoionization width with increasing n 0 is obtained, the result for asymmetric pairs is counterintuitive - for a fixed n i of the ionizing atom of the pair, the autoionization width strongly increases with decreasing n d of the de-excited atom. For H Rydberg atoms this increase reaches two orders of magnitude at the maximum of the n d dependence, and the same type of counterintuitive behavior is exhibited also by Na, Rb and Cs atoms. This is a purely quantum-mechanical effect, which points towards existence of optimal (we call them \\'Tom\\' and \\'Jerry\\' for \\'big\\' and \\'small\\') pairs of Rydberg atoms with respect to autoionization efficiency. Building on the model of population redistribution in cold Rydberg gases proposed in [1], we demonstrate that population evolution following the initial laser excitation of Rydberg atoms in state n 0 would eventually lead to the formation of such Tom-Jerry pairs with which feature autoionization widths that are enhanced by several orders of magnitude compared to that of two atoms in the initial laser-excited state n 0. We also show that in the high-density regime of cold Rydberg gas experiments the ionization rate of Tom-Jerry pairs can be substantially larger than the blackbody radiation-induced photoionization rate. © 2016 IOP Publishing Ltd.

  5. Transperance Me I Want to be Visible: Gay Gaze in Tom Ford’s film A Single Man

    Directory of Open Access Journals (Sweden)

    Selen Gokcem

    2012-04-01

    Full Text Available Classic gaze theory that was underlined by Laura Mulvey in 1975 which claims the male gaze objectifies woman and turns the woman into a sex object, is lack in the explaining gaze from man to man. In Tom Ford’s A Single Man the gaze is used from man to man different from man to woman and it is not perceived as something negative. By providing a queer gaze analysis, this article will show how homosexual people live their intimate feelings by gaze and how gay gaze can be different from the classic gaze in a way that it does not reduces the other one in an interior position.

  6. Recuperación del borde costero, la transformación de una ciudad. Tomé

    Directory of Open Access Journals (Sweden)

    Marcela Moraga Mansoulet

    2015-03-01

    Desde la visión de una ciudad industrial y textil; declarada en 1958, Puerto Mayor, para el comercio e intercambio con el extranjero, a la decadencia de este mismo puerto, producto de la llegada de ferrocarriles, y el cambio paulatino de rol de la ciudad, es que actualmente Tomé se puede definir como una ciudad en proceso de transformación y transición, dejando atrás su histórico pasado, para transformarse en una ciudad enfocada principalmente al desarrollo de turismo, como objetivo principal, de acuerdo a las necesidades de los tiempos que hoy transcurren.

  7. Las enfermedades mentales según Tomás de Aquino : sobre el concepto de enfermedad

    OpenAIRE

    2008-01-01

    Este artículo es la primera parte de un estudio sobre las enfermedades mentales según santo Tomás. Aquí se exponen los temas de las fuentes médico-biológicas del Aquinate (fundamentalmente Aristóteles, Galeno, Nemesio y Avicena), la naturaleza de la enfermedad, su relación con las pasiones del alma y algunas consecuencias que se siguen para el tema de la enfermedad mental. En un artículo posterior se entrará en el detalle de las categorías psicopatológicas que aparecen en las obras del Aquina...

  8. Cruzando fronteras nacionales: hacia una cartografía del ensayismo de Tomás Segovia

    NARCIS (Netherlands)

    Houvenaghel, E.M.H.

    2014-01-01

    El poeta y ensayista hispanomexicano Tomás Segovia (Valencia 1927 – México 2011) vivió entre diferentes mundos: es de origen español y se exilió primero a Francia y después a a México, país en el que residió durante más de cuatro décadas, antes de regresar a Francia y España en 1985. Con el fin de

  9. Cruzando fronteras nacionales: hacia una cartografía del ensayismo de Tomás Segovia

    NARCIS (Netherlands)

    Houvenaghel, E.M.H.

    2014-01-01

    El poeta y ensayista hispanomexicano Tomás Segovia (Valencia 1927 – México 2011) vivió entre diferentes mundos: es de origen español y se exilió primero a Francia y después a a México, país en el que residió durante más de cuatro décadas, antes de regresar a Francia y España en 1985. Con el fin de c

  10. Semen quality and interval to sterility in tom cats treated with a 9.4 mg deslorelin implant.

    Science.gov (United States)

    Romagnoli, Stefano; Baldan, Anna; Righetti, Camilla; Milani, Chiara; Mollo, Antonio; Stelletta, Calogero

    2017-02-01

    Objectives Gonadotropin-releasing hormone (GnRH) agonists like deslorelin are being increasingly used in tom cats for their efficacy in controlling reproductive behaviour and fertility. Deslorelin implants have been widely available in Europe since 2008. Little, if anything, is known about the interval between treatment and onset of sterility, as well as semen quality, after treatment in tom cats. The purpose of this study was to investigate semen quality and interval to sterility in tom cats treated with a 9.4 mg deslorelin implant. Methods Fifteen healthy adult tom cats were treated with a 9.4 mg deslorelin implant (Suprelorin 12). For each cat, semen collection and a GnRH stimulation test (intramuscular administration of 50 μg gonadorelin [Fertagyl], followed by blood sampling 1 h later, to assay serum testosterone) were performed on the first consultation and then repeated every 15 days until complete sterility was achieved. Semen collection was performed by introducing a 14 cm, open-end feline catheter (Argyle) 9 cm into the distal urethra 10 mins after sedation by intramuscular injection of 100 μg/kg medetomidine (Domitor). Results Semen collection was not successful in all cats at each attempt. In the first month after treatment, the semen of only four cats could be evaluated, while the semen of eight cats could be evaluated during the second and third months of the study. Semen quality (ejaculate volume, progressive motility and morphological abnormalities) improved slightly during the first 19-25 days in 2/4 cats, and in 1/4 cats motility was still very high (80%) 25 days post-treatment (PT), but we have no data regarding fertility prior to treatment in this cat. The last cat never produced spermatozoa. Subsequently, semen quality gradually worsened in all cats from 30 days onwards. At 70 days PT, one cat was still potentially fertile. After 72 days all cats were sterile. Conclusions and relevance Semen quality increased slightly in treated cats during

  11. S. Tomé e Príncipe, um pequeno Estado em contacto com o mundo

    OpenAIRE

    Brito, Brígida

    2004-01-01

    São Tomé caracteriza-se pela pequena dimensão e natureza insular, em forma de arquipélago, que lhe confere elevado grau de isolamento. Neste contexto os contactos com o exterior foram entendidos desde a independência como uma necessidade absoluta, apesar das diferentes orientações políticas seguidas. Em 1975 privilegiou-se o relacionamento com Cuba, URSS, RDA e China. Com a transição política associada a alguma liberalização económica, privilegiaram-se outro tipo de contactos do ponto de vist...

  12. Cross-sex hormone use, functional health and mental well-being among transgender men (Toms) and Transgender Women (Kathoeys) in Thailand.

    Science.gov (United States)

    Gooren, Louis J; Sungkaew, Tanapong; Giltay, Erik J; Guadamuz, Thomas E

    2015-01-01

    There exists limited understanding of cross-sex hormone use and mental well-being among transgender women and, particularly, among transgender men. Moreover, most studies of transgender people have taken place in the Global North and often in the context of HIV. This exploratory study compared 60 transgender men (toms) with 60 transgender women (kathoeys) regarding their use of cross-sex hormones, mental well-being and acceptance by their family. Participants also completed a dispositional optimism scale (the Life Orientation Test Revised), the Social Functioning Questionnaire and the Short Form Health Survey 36 assessing their profile of functional health and mental well-being. Cross-sex hormones were used by 35% of toms and 73% of kathoeys and were largely unsupervised by health-related personnel. There were no differences in functional health and mental well-being among toms and kathoeys. However, toms currently using cross-sex hormones scored on average poorer on bodily pain and mental health, compared to non-users. Furthermore, compared to non-users, cross-sex hormone users were about eight times and five times more likely to be associated with poor parental acceptance among toms and kathoeys, respectively. This study was the first to compare cross-sex hormone use, functional health and mental well-being among transgender women and transgender men in Southeast Asia.

  13. Rapid phenotyping of the tomato fruit model, Micro-Tom, with a portable VIS-NIR spectrometer.

    Science.gov (United States)

    Ecarnot, Martin; Bączyk, Paulina; Tessarotto, Lydie; Chervin, Christian

    2013-09-01

    Tomato (Solanum lycopersicum) quality traits such as juice soluble solid content (Brix), juice pH, color parameters (Hue and Chroma), firmness and water content, are critical factors for fruit quality assessment. The need for screening very large numbers of fruit has led to the development of a high-throughput method using visible-near infrared (VIS-NIR) spectrometry. We are reporting here a set of results obtained with a portable spectrometer using the 350-2500 nm range, showing good prediction of the quality traits cited above, over a wide range of developmental stages from immature green to ripe tomato fruit, cv. Micro-Tom. This is a rather good set of quality traits compared to previous publications predicting tomato quality with VIS-NIR spectrometry, and the prediction is robust, as it was obtained by grouping sets of different operators. This would be a useful tool to phenotype hundreds of Micro-Tom per day, making it possible to follow the dynamics of the described parameters on growing fruits. Thus the method can be used to study the biochemistry and physiology of fruit development in planta.

  14. Retention and Attrition of Umbundu in São Tomé and Príncipe

    Directory of Open Access Journals (Sweden)

    Gerardo Augusto Lorenzino

    2015-12-01

    Full Text Available A major event in the modern history of São Tomé and Príncipe, located in the Gulf of Guinea, was the recruitment of contracted labor from Angola, Mozambique, and Cape Verde between 1870 and 1960. This article will address one linguistic effect of this large-scale migration, namely, the retention and attrition of the Umbundu language spoken by the Tongas, who are descendants of the indentured laborers who never repatriated back to their homes in Africa. As opposed to noncontact Umbundu, the Tonga Umbundu (TUm of São Tomé has a simplified nominal class system and significant borrowings from the Portuguese lexicon, which became part of the TUm class system through incorporation. The sociolinguistic factors that will be considered in evaluating the nature of the Tongas’ linguistic heritage are (a the language situation that best explains the retention of Umbundu and (b the typological distance between TUm, Afro-Portuguese Creoles, and Portuguese language.

  15. Tomás López Medel y sus instrucciones para defensores de Indios: una propuesta innovadora

    Directory of Open Access Journals (Sweden)

    Cunill, Caroline

    2011-12-01

    Full Text Available Although in recent years both the trajectory and the political thought of Tomás Lopez Medel have attracted the attention of several scholars, his instructions to defenders of Indians has gone unnoticed. However, the innovative proposals developed by the oidor are essential in order to highlight the construction of indigenous advocacy in the second half of the Sixteenth century. Moreover, this article also examines the defender of Indians’ role, as well as the principles that underlay the creation of this office in the Americas.

    Aunque en los últimos años la carrera y el pensamiento político del oidor Tomás López Medel han llamado la atención de los estudiosos, sus instrucciones para defensores de Indios han pasado desapercibidas. Sin embargo, esta innovadora propuesta es esencial para comprender cómo nació y cómo prosperó este oficio en la segunda mitad del siglo XVI. Por otra parte, también se analizarán las funciones del defensor de Indios con el fin de acercarse a los principios teóricos que sirvieron de fundamento a la creación del cargo en América.

  16. Los santos dominicos y la propaganda inquisitorial en el convento de Santo Tomás de Ávila

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    Caballero Escamilla, Sonia

    2009-06-01

    Full Text Available In this study, we analyze the paintings of the Saint Domingo of Guzmán, Saint Thomas of Aquino and Saint Peter of Verona of the monastery of Saint Thomas in Ávila and their iconography in relation to the original historical context. The interpretation of the images shows some aspects about the person who commissions the paintings and who designed the message, the inquisitor Torquemada, as well as his aim.

    En este artículo analizamos las pinturas de Santo Domingo de Guzmán, Santo Tomás de Aquino y San Pedro de Verona del Convento de Santo Tomás de Ávila y su iconografía en relación con el contexto histórico original. La interpretación de las imágenes revela algunos aspectos de la persona que, hipotéticamente, encargó las pinturas y que diseñó el mensaje, el inquisidor Torquemada, así como sus objetivos.

  17. Availability of Micro-Tom mutant library combined with TILLING in molecular breeding of tomato fruit shelf-life.

    Science.gov (United States)

    Okabe, Yoshihiro; Asamizu, Erika; Ariizumi, Tohru; Shirasawa, Kenta; Tabata, Satoshi; Ezura, Hiroshi

    2012-06-01

    Novel mutant alleles of an ethylene receptor Solanum lycopersicum ETHYLENE RESPONSE1 (SlETR1) gene, Sletr1-1 and Sletr1-2, were isolated from the Micro-Tom mutant library by TILLING in our previous study. They displayed different levels of impaired fruit ripening phenotype, suggesting that these alleles could be a valuable breeding material for improving shelf life of tomato fruit. To conduct practical use of the Sletr1 alleles in tomato breeding, genetic complementation analysis by transformation of genes carrying each allele is required. In this study, we generated and characterized transgenic lines over-expressing Sletr1-1 and Sletr1-2. All transgenic lines displayed ethylene insensitive phenotype and ripening inhibition, indicating that Sletr1-1 and Sletr1-2 associate with the ethylene insensitive phenotype. The level of ethylene sensitivity in the seedling was different between Sletr1-1 and Sletr1-2 transgenic lines, whereas no apparent difference was observed in fruit ripening phenotype. These results suggested that it is difficult to fine-tune the extent of ripening by transgenic approach even if the weaker allele (Sletr1-2) was used. Our present and previous studies indicate that the Micro-Tom mutant library combined with TILLING could be an efficient tool for exploring genetic variations of important agronomic traits in tomato breeding.

  18. Effects of packaging materials on the aroma stability of Thai 'tom yam' seasoning powder as determined by descriptive sensory analysis and gas chromatography-mass spectrometry.

    Science.gov (United States)

    Leelaphiwat, Pattarin; Harte, Janice B; Auras, Rafael A; Ong, Peter Kc; Chonhenchob, Vanee

    2017-04-01

    Changes in the aroma characteristics of Thai 'tom yam' seasoning powder, containing lemongrass, galangal and kaffir lime leaf, as affected by different packaging materials were assessed using quantitative descriptive analysis (QDA) and gas chromatography-mass spectrometry (GC-MS). The descriptive aroma attributes for lemongrass, galangal and kaffir lime leaf powders were developed by the QDA panel. The mixed herb and spice seasoning powder was kept in glass jars closed with different packaging materials (Nylon 6, polyethylene terephthalate (PET) and polylactic acid (PLA)) stored at 38 °C (accelerated storage condition), and evaluated by the trained QDA panel during storage for 49 days. The descriptive words for Thai 'tom yam' seasoning powder developed by the trained panelists were lemongrass, vinegary and leafy for lemongrass, galangal and kaffir lime leaf dried powder, respectively. The aroma intensities significantly (P ≤ 0.05) decreased with increased storage time. However, the intensity scores for aroma attributes were not significantly (P > 0.05) different among the packaging materials studied. The major components in Thai 'tom yam' seasoning powder, quantified by GC-MS, were estragole, bicyclo[3.1.1]heptane, β-bisabolene, benzoic acid and 2-ethylhexyl salicylate. The concentrations of major aroma compounds significantly (P ≤ 0.05) decreased with storage time. Aroma stability of Thai 'tom yam' powder can be determined by descriptive sensory evaluation and GC-MS analysis. Nylon, PET and PLA exhibited similar aroma barrier properties against key aroma compounds in Thai 'tom yam'. This information can be used for prediction of aroma loss through packaging materials during storage of Thai 'tom yam'. © 2016 Society of Chemical Industry. © 2016 Society of Chemical Industry.

  19. Templanza y continencia en Tomás de Aquino : razones para una concepción no dualista de la virtud moral

    OpenAIRE

    Serrano del Pozo, Ignacio

    2008-01-01

    El propósito de esta investigación es mostrar las razones que tiene Tomás de Aquino para privilegiar una moral de la templanza por sobre una de mera continencia. Pero más allá de detenerse en los pocos artículos que Santo Tomás dedica a comparar ambas disposiciones, el fin de nuestro trabajo es, a partir de los textos referidos a la naturaleza de la virtud moral, mostrar por qué sólo la templanza puede ser considerada una virtud, mientras la continencia es una “mezcla" de virtud y desorden. E...

  20. El comentario de Santo Tomás a la política de Aristóteles: un análisis desde el prooemium

    Directory of Open Access Journals (Sweden)

    Barrera, Jorge Martínez

    2006-01-01

    Full Text Available Os prólogos dos comentários de Tomás de Aquino às obras de Aristóteles são de suma importância, porque neles o autor apresenta o que se poderia denominar "o marco conceptual" do trabalho que está empreendendo. No caso do Comentário à Política, o conceito fundamental é o conceito de natureza. A afirmação de que existe uma "imitação da natureza" significa, para Tomás, muito mais do que representou para seus antecessores

  1. Analysis of school life in the second basic cycle of the municipality of Tomé: perception of the actors

    Directory of Open Access Journals (Sweden)

    Oscar Nail Kröyer

    2011-11-01

    Full Text Available This paper presents the results and conclusions of a study on school life made in the town of Tomé, Chile. This research was conducted through questionnaires applied in 10 municipal schools of basic education. The subjects of the sample are heads of the institutions and students, teachers and parents of selected courses. The results show that people assess positively to school life in different establishments, but the study shows that there is a more positive perception by students of the centers of other educators. On the other hand it should be noted that there is poor perception of teachers’ work in the establishments and this phenomenon is the main problem for students and parents. It also highlights the limited parental involvement in school areas. The importance of this study relates is that provides information to improve the management of coexistence both in schools and the community as a whole.

  2. Black Humour Spaces in Cinema and Literature: Yorgos Lanthimos' The Lobster and Tom McCarthy's Satin Island

    Directory of Open Access Journals (Sweden)

    Vincenzo Maggitti

    2016-11-01

    Full Text Available Il saggio ruota intorno a due diverse forme di umorismo nero nella cinematografia e nella letteratura contemporanee. Partendo da una recente riflessione sull’intervento di Jonathan Coe su cosa ne sia oggi dell’umorismo, vengono discusse due opere – il film The Lobster  e il romanzo Satin Island – che rileggono il mondo attuale attraverso la lente umoristica, nell’accezione più scura e corrosiva di atteggiamenti ecologicamente corretti. Il film di Lanthimos ripristina la caccia come modalità universale di rapporto uomo-animale, mentre il romanzo di Tom McCarthy ribalta la responsabilità del danno ambientale in meritevole atto ecologico. Nella chiave di lettura dell’autore del saggio l’umorismo riprende la svolta antropologica che ne caratterizza la funzione più straniante.

  3. The amyloid beta-peptide is imported into mitochondria via the TOM import machinery and localized to mitochondrial cristae

    DEFF Research Database (Denmark)

    Hansson Petersen, Camilla A; Alikhani, Nyosha; Behbahani, Homira

    2008-01-01

    The amyloid beta-peptide (Abeta) has been suggested to exert its toxicity intracellularly. Mitochondrial functions can be negatively affected by Abeta and accumulation of Abeta has been detected in mitochondria. Because Abeta is not likely to be produced locally in mitochondria, we decided...... to investigate the mechanisms for mitochondrial Abeta uptake. Our results from rat mitochondria show that Abeta is transported into mitochondria via the translocase of the outer membrane (TOM) machinery. The import was insensitive to valinomycin, indicating that it is independent of the mitochondrial membrane...... potential. Subfractionation studies following the import experiments revealed Abeta association with the inner membrane fraction, and immunoelectron microscopy after import showed localization of Abeta to mitochondrial cristae. A similar distribution pattern of Abeta in mitochondria was shown...

  4. Tomás Romay Chacón y Carlos J. Finlay Barres hitos de pensamiento cubano en salud

    Directory of Open Access Journals (Sweden)

    María Elena Macías Llanes

    Full Text Available El objetivo del texto radica en resaltar algunos elementos de pensamiento en salud de los notables médicos cubanos Tomás Romay y Carlos J. Finlay. Se analizan sus posturas y connotación acerca del nexo entre la ciencia y la sociedad. El método investigativo utilizado ha sido la revisión documental en publicaciones periódicas, libros y repositorio de tesis. Destaca en este acercamiento la conmemoración en agosto del centenario de la muerte de Finlay (La Habana, 20 de agosto de 1915. Por lo cual este sucinto trabajo constituye un homenaje a su obra y, a su vez, al ideario de vanguardia manifiesto en la labor médica de ambos hombres de ciencia.

  5. Poetic Forms & Existentialism in Tom Leonard’s access to the silence: poems and posters, 1984–2004

    Directory of Open Access Journals (Sweden)

    Theresa Muñoz

    2017-01-01

    Full Text Available This article on Glasgow poet Tom Leonard explores his visual poetry and his poems with existentialist leanings in his fourth poetry collection: 'access to the silence: poems and posters, 1984–2004'. This paper analyses Leonard’s more experimental forms such as his poetry sequences and poster poems, as well as taking a look at his explorations in existentialism. The article aims to widen discussion on Leonard’s work and find similarities in form and content to other poets in the UK. Previous criticism focuses solely on his previous work in urban phonetic dialect, and through discussing how Leonard’s poems use poetic forms to explore philosophical concepts, this article aims to address this imbalance.

  6. Isolation and characterization of an IgNAR variable domain specific for the human mitochondrial translocase receptor Tom70.

    Science.gov (United States)

    Nuttall, Stewart D; Krishnan, Usha V; Doughty, Larissa; Pearson, Kylie; Ryan, Michael T; Hoogenraad, Nicholas J; Hattarki, Meghan; Carmichael, Jennifer A; Irving, Robert A; Hudson, Peter J

    2003-09-01

    The new antigen receptor (IgNAR) from sharks is a disulphide bonded dimer of two protein chains, each containing one variable and five constant domains, and functions as an antibody. In order to assess the antigen-binding capabilities of isolated IgNAR variable domains (VNAR), we have constructed an in vitro library incorporating synthetic CDR3 regions of 15-18 residues in length. Screening of this library against the 60 kDa cytosolic domain of the 70 kDa outer membrane translocase receptor from human mitochondria (Tom70) resulted in one dominant antigen-specific clone (VNAR 12F-11) after four rounds of in vitro selection. VNAR 12F-11 was expressed into the Escherichia coli periplasm and purified by anti-FLAG affinity chromatography at yields of 3 mg x L(-1). Purified protein eluted from gel filtration columns as a single monomeric protein and CD spectrum analysis indicated correct folding into the expected beta-sheet conformation. Specific binding to Tom70 was demonstrated by ELISA and BIAcore (Kd = 2.2 +/- 0.31 x 10(-9) m-1) indicating that these VNAR domains can be efficiently displayed as bacteriophage libraries, and selected against target antigens with an affinity and stability equivalent to that obtained for other single domain antibodies. As an initial step in producing 'intrabody' variants of 12F-11, the impact of modifying or removing the conserved immunoglobulin intradomain disulphide bond was assessed. High affinity binding was only retained in the wild-type protein, which combined with our inability to affinity mature 12F-11, suggests that this particular VNAR is critically dependent upon precise CDR loop conformations for its binding affinity.

  7. Evaluation of four Agrobacterium tumefaciens strains for the genetic transformation of tomato (Solanum lycopersicum L.) cultivar Micro-Tom.

    Science.gov (United States)

    Chetty, V J; Ceballos, N; Garcia, D; Narváez-Vásquez, J; Lopez, W; Orozco-Cárdenas, M L

    2013-02-01

    KEY MESSAGE : Agrobacterium tumefaciens strains differ not only in their ability to transform tomato Micro-Tom, but also in the number of transgene copies that the strains integrate in the genome. The transformation efficiency of tomato (Solanum lycopersicum L.) cv. Micro-Tom with Agrobacterium tumefaciens strains AGL1, EHA105, GV3101, and MP90, harboring the plasmid pBI121 was compared. The presence of the nptII and/or uidA transgenes in regenerated T(0) plants was determined by PCR, Southern blotting, and/or GUS histochemical analyses. In addition, a rapid and reliable duplex, qPCR TaqMan assay was standardized to estimate transgene copy number. The highest transformation rate (65 %) was obtained with the Agrobacterium strain GV3101, followed by EHA105 (40 %), AGL1 (35 %), and MP90 (15 %). The mortality rate of cotyledons due to Agrobacterium overgrowth was the lowest with the strain GV3101. The Agrobacterium strain EHA105 was more efficient than GV3101 in the transfer of single T-DNA insertions of nptII and uidA transgenes into the tomato genome. Even though Agrobacterium strain MP90 had the lowest transformation rate of 15 %, the qPCR analysis showed that the strain MP90 was the most efficient in the transfer of single transgene insertions, and none of the transgenic plants produced with this strain had more than two insertion events in their genome. The combination of higher transformation efficiency and fewer transgene insertions in plants transformed using EHA105 makes this Agrobacterium strain optimal for functional genomics and biotechnological applications in tomato.

  8. Profiling of genes related to cross protection and competition for NbTOM1 by HLSV and TMV.

    Science.gov (United States)

    Wen, Yi; Lim, Grace Xiao-Yun; Wong, Sek-Man

    2013-01-01

    Cross protection is the phenomenon through which a mild strain virus suppresses symptoms induced by a closely related severe strain virus in infected plants. Hibiscus latent Singapore virus (HLSV) and Tobacco mosaic virus (TMV) are species within the genus tobamovirus. HLSV can protect Nicotianabenthamiana against TMV-U1 strain, resulting in mild symptoms instead of severe systemic necrosis. The mechanism of cross protection between HLSV and TMV is unknown. In the past, some researchers suggest that the protecting virus strain might occupy virus-specific replication sites within a cell leaving no room for the challenge virus. Quantitative real-time RT-PCR was performed to detect viral RNA levels during cross protection. HLSV accumulation increased in cross protected plants compared with that of single HLSV infected plants, while TMV decreased in cross protected plants. This suggests that there is a competition for host factors between HLSV and TMV for replication. To investigate the mechanism under the cross protection between HLSV and TMV, microarray analysis was conducted to examine the transcriptional levels of global host genes during cross protection, using Tobacco Gene Expression Microarray, 4 x 44 k slides. The transcriptional level of some host genes corresponded to accumulation level of TMV. Some host genes were up-regulated only by HLSV. Tobamovirus multiplication gene 1 (TOM1), essential for tobamovirus multiplication, was involved in competition for replication by HLSV and TMV during cross protection. Both HLSV and TMV accumulation decreased when NbTOM1 was silenced. A large quantity of HLSV resulted in decreased TMV accumulation in HLSV+TMV (100:1) co-infection. These results indicate that host genes involved in the plant defense response and virus multiplication are up-regulated by challenge virus TMV but not by protecting virus HLSV during cross protection.

  9. Strong enhancement of Penning ionization for asymmetric atom pairs in cold Rydberg gases: the Tom and Jerry effect

    Science.gov (United States)

    Efimov, D. K.; Miculis, K.; Bezuglov, N. N.; Ekers, A.

    2016-06-01

    We consider Penning ionization of Rydberg atom pairs as an Auger-type process induced by the dipole-dipole interaction and employ semiclassical formulae for dipole transitions to calculate the autoionization width as a function of the principal quantum numbers, n d , n i , of both atoms. While for symmetric atom pairs with {n}d={n}i={n}0 the well-known increase of the autoionization width with increasing n 0 is obtained, the result for asymmetric pairs is counterintuitive—for a fixed n i of the ionizing atom of the pair, the autoionization width strongly increases with decreasing n d of the de-excited atom. For H Rydberg atoms this increase reaches two orders of magnitude at the maximum of the n d dependence, and the same type of counterintuitive behavior is exhibited also by Na, Rb and Cs atoms. This is a purely quantum-mechanical effect, which points towards existence of optimal (we call them ‘Tom’ and ‘Jerry’ for ‘big’ and ‘small’) pairs of Rydberg atoms with respect to autoionization efficiency. Building on the model of population redistribution in cold Rydberg gases proposed in [1], we demonstrate that population evolution following the initial laser excitation of Rydberg atoms in state n 0 would eventually lead to the formation of such Tom-Jerry pairs with {n}i\\gt {n}0\\gt {n}d which feature autoionization widths that are enhanced by several orders of magnitude compared to that of two atoms in the initial laser-excited state n 0. We also show that in the high-density regime of cold Rydberg gas experiments the ionization rate of Tom-Jerry pairs can be substantially larger than the blackbody radiation-induced photoionization rate.

  10. Wild meat consumption on São Tomé Island, West Africa: implications for conservation and local livelihoods

    Directory of Open Access Journals (Sweden)

    Mariana Carvalho

    2015-09-01

    Full Text Available The importance of wild meats for rural people is well documented in tropical forests worldwide. However, the case of oceanic islands remains relatively poorly studied. We assess the contribution made by wild meats to the diets of rural inhabitants in the Island of São Tomé, characterize the relative importance of native and introduced fauna, and discuss the implications of wild meat consumption on rural livelihoods and on the conservation of the resident fauna. Using semistructured interviews, we assessed animal protein consumption in 10 communities (716 household-weeks, around the vicinity of the island's main protected area, Obô Natural Park. Fish and the introduced West African giant snail (Archachatina marginata are the most important sources of protein for rural inhabitants, with wild terrestrial vertebrates being consumed by only a small fraction of sampled households. Significantly higher amounts of wild snail and wild mammal meat are consumed in more remote areas with poorer families depending more on snails, and richer households on fruit bats or introduced mammals. Although eaten in relatively small numbers per household, consumption of wild birds is widespread, thus when extrapolated to the island's entire rural population, this practice is likely to be unsustainable, particularly for endemic pigeons that are also commercially hunted. Our results suggest that rural populations in São Tomé largely depend on protein from introduced wild species, with native and endemic fauna constituting less important sources. However, endemic birds and native fruit bats are extensively harvested for household consumption and constitute a commonly used resource that urgently needs to be regulated.

  11. TOMS/Earth Probe UV Reflectivity Monthly L3 Global 1x1.25 deg Lat/Lon Grid V008

    Data.gov (United States)

    National Aeronautics and Space Administration — This data product contains TOMS/Earth Probe UV Reflectivity Monthly L3 Global 1x1.25 deg Lat/Lon Grid Version 8 data in ASCII format. (The shortname for this Level-3...

  12. [Suya es la radio : 50 aniversario de Radio Alcoy, entrevista a Mario Silvestre, Antonio Doménech y Tomás Gisbert

    OpenAIRE

    Radio Alcoy; Rubio Orsi, Lorenzo; Gallego Fernández, María Llanos; Gisbert, Tomás; Doménech, Antonio; Cremades Zaragoza, Remigio; Esplugues Jordá, Francisco; Silvestre Pons, Mario

    1981-01-01

    Grabación conmemorativa por el cincuentenario de la emisora EAJ-12, Radio Alcoy en base a los recuerdos de tres locutores históricos de la emisora: Mario Silvestre, Antonio Doménech y Tomás Gisbert

  13. ¿Qué es filosofía? Un diálogo entre Edmund Husserl y Tomás de Aquino.[Reseña

    OpenAIRE

    Moros, E. (Enrique)

    2002-01-01

    Reseña de Edith STEIN, ¿Qué es filosofía? Un diálogo entre Edmund Husserl y Tomás de Aquino, Trad. Alicia Valero Martín, Encuentro, («Opuscula Philosophica 6»), Madrid 2001, 45 pp., ISBN 84-7490- 639-3.

  14. Role of PINK1 binding to the TOM complex and alternate intracellular membranes in recruitment and activation of the E3 ligase Parkin.

    Science.gov (United States)

    Lazarou, Michael; Jin, Seok Min; Kane, Lesley A; Youle, Richard J

    2012-02-14

    Mutations in the mitochondrial kinase PINK1 and the cytosolic E3 ligase Parkin can cause Parkinson's disease. Damaged mitochondria accumulate PINK1 on the outer membrane where, dependent on kinase activity, it recruits and activates Parkin to induce mitophagy, potentially maintaining organelle fidelity. How PINK1 recruits Parkin is unknown. We show that endogenous PINK1 forms a 700 kDa complex with the translocase of the outer membrane (TOM) selectively on depolarized mitochondria whereas PINK1 ectopically targeted to the outer membrane retains association with TOM on polarized mitochondria. Inducibly targeting PINK1 to peroxisomes or lysosomes, which lack a TOM complex, recruits Parkin and activates ubiquitin ligase activity on the respective organelles. Once there, Parkin induces organelle selective autophagy of peroxisomes but not lysosomes. We propose that the association of PINK1 with the TOM complex allows rapid reimport of PINK1 to rescue repolarized mitochondria from mitophagy, and discount mitochondrial-specific factors for Parkin translocation and activation. Copyright © 2012 Elsevier Inc. All rights reserved.

  15. La sacra doctrina como ciencia imperfecta quoad nos en Tomás de Aquino: Nuevas reflexiones a partir de algunas ediciones críticas recientes

    Directory of Open Access Journals (Sweden)

    Francisco Romero Carrasquillo

    2016-12-01

    Full Text Available Como es bien sabido, en su Suma teológica Tomás de Aquino defiende desde una perspectiva aristotélica la naturaleza científica de la sacra doctrina, proponiéndola como una ciencia subalterna al conocimiento que Dios tiene de sí mismo.  La interpretación de Tomás en torno a la doctrina aristotélica de la ciencia le permite proponer que las conclusiones de la sacra doctrina se reducen a los artículos de la fe como a sus primeros principios.  Lo que no es bien sabido, sin embargo, es que Tomás en otros textos cambia su postura sobre el modo en que la sacra doctrina llena los requisitos para ser ciencia.  Esto ha sido puesto en evidencia en parte por algunas ediciones críticas recientes, como la de la Lectura Romana, realizada por Boyle, y especialmente la del prólogo al Comentario a las Sentencias, por Adriano Oliva.  Si bien los artículos de la fe son evidentes en sí mismos (per se, estos textos, vistos cronológicamente, demuestran que a través de su carrera Tomás vacila en reconocer que desde nuestra perspectiva (quoad nos los artículos no son evidentes ni demostrables, sino que son objetos de fe religiosa.  A través de estos textos Tomás progresivamente admite que existe una imperfección en el modo en que la conocemos en esta vida (in via; por tanto, la sacra doctrina en cierto modo se queda corta de la ratio perfecta de ciencia, al menos quoad nos.

  16. Arte y revolución: Sobre los fotomontajes olvidados de Tomás Maldonado Art and revolution: on the forgotten photomontages of Tomás Maldonado

    Directory of Open Access Journals (Sweden)

    Daniela Lucena

    2012-08-01

    Full Text Available Este artículo presenta un análisis sobre los fotomontajes realizados por el artista Tomás Maldonado entre 1946 y 1947 para Orientación, el periódico oficial del Partido Comunista Argentino. Estas producciones eran desconocidas (o silenciadas por los historiadores del arte argentino hasta los inicios de la investigación que emprendí en el año 2003 y que se materializó en mi tesis doctoral (2010, e incluso hasta hace muy poco tiempo no se incluían en el repertorio de obras del artista. Desde la perspectiva aquí propuesta, en cambio,los fotomontajes de Maldonado constituyen dos intervenciones cruciales para abordar el intenso vínculo entre arte, revolución y política que atraviesa el proyecto de la vanguardia de arte concreto argentina. Por un lado, porque remiten a la militancia de varios miembros de la Asociación Arte ConcretoInvención en las filas del comunismo local. Por otro, porque son producciones en las cuales es posible observar la estrecha relación existente entre la propuesta del concretismo argentino impulsado por Maldonado y el programa puesto en marcha por las vanguardias soviéticas en los años posteriores a la revolución bolchevique

  17. Essential oil composition and antimicrobial activity of three Zingiberaceae from S.Tomé e Príncipe.

    Science.gov (United States)

    Martins, A P; Salgueiro, L; Gonçalves, M J; da Cunha, A P; Vila, R; Cañigueral, S; Mazzoni, V; Tomi, F; Casanova, J

    2001-08-01

    The essential oil composition of three Zingiberaceae widely used as medicinal aromatic plants from S. Tomé and Príncipe: Aframomum danielli (Hook. f.) K. Schum., Curcuma longa L. and Zingiber officinale Rosc. was studied. Two samples of the essential oils from fruit of A. danielli and from rhizomes of the other two species, were obtained by hydrodistillation and analyzed by GC, GC-MS, and (13)C-NMR. The essential oil from fruits of A. danielli has been studied for the first time and was characterised by its high content of monoterpenes, with 1,8-cineole (25.5 - 34.4 %) the major constituent, followed by beta-pinene (14.1 - 15.2 %) and alpha-terpineol (9.9 - 12.1 %). Essential oils from the rhizomes of C. longa contained a lower content of ar-turmerone (4.0 - 12.8 %) than those reported in the literature for C. longa from other origins (24.7 - 31.4 %), whereas the results for Z. officinale essential oils were in accordance with the literature data. The essential oils of A. danielli and Z. officinale showed antimicrobial activity against all Gram-positive and Gram-negative bacteria tested, as well as against yeasts and filamentous fungi, using the agar diffusion method.

  18. As inovações de Tom Zé na linguagem da canção popular dos anos 1970

    Directory of Open Access Journals (Sweden)

    Herom Vargas

    2012-12-01

    Full Text Available O objetivo deste artigo é discutir alguns aspectos da experimentação do compositor brasileiro Tom Zé em três de seus cinco discos lançados nos anos 1970, dentro de um cenário de exceção institucional por conta da ditadura militar e de expansão das indústrias culturais. Do cantor, serão tratadas canções dos discos: Se o caso é chorar (Continental - 1972, Todos os olhos (Continental - 1973 e Estudando o samba (Continental - 1975. A noção básica de experimentação utilizada é de Umberto Eco (1970. Outro conceito para a discussão do experimentalismo é o de “canção crítica”, desenvolvido por S.C. Naves (2010. Como horizonte teórico, a canção popular será tratada como “texto semiótico”, conforme a semiótica da cultura de I.M. Lótman (1996. Os aspectos de inovação serão analisados internamente à própria linguagem híbrida da canção (letra, canto, música e performance e nas relações externas entre canção e contexto cultural.

  19. Small and remarkable: The Micro-Tom model system as a tool to discover novel hormonal functions and interactions.

    Science.gov (United States)

    Campos, Marcelo Lattarulo; Carvalho, Rogério Falleiros; Benedito, Vagner Augusto; Peres, Lázaro Eustáquio Pereira

    2010-03-01

    Hormones are molecules involved in virtually every step of plant development and studies in this field have been shaping plant physiology for more than a century. The model plant Arabidopsis thaliana, long used as a tool to study plant hormones, lacks significant important developmental traits, such as fleshy climacteric fruit, compound leaf and multicellular trichomes, suggesting the necessity for alternative plant models. An attractive option often used is tomato, a species also of major economic importance, being ideal to bring together basic and applied plant sciences. The tomato Micro-Tom (MT) cultivar makes it possible to combine the direct benefits of studying a crop species with the fast life cycle and small size required for a suitable biological model. However, few obscure questions are constantly addressed to MT, creating a process herein called "MT mystification". In this work we present evidence clarifying these questions and show the potential of MT, aiming to demystify it. To corroborate our ideas we showed that, by making use of MT, our laboratory demonstrated straightforwardly new hormonal functions and also characterized a novel antagonistic hormonal interaction between jasmonates and brassinosteroids in the formation of anti-herbivory traits in tomato.

  20. Emergencia de la conciencia intelectiva. La teoría creacionista según Tomás de Aquino

    Directory of Open Access Journals (Sweden)

    Lorenzo Vicente Burgoa

    2016-10-01

    Full Text Available La pregunta «¿de dónde venimos?" sigue siendo de interés, para saber qué somos y hacia dónde vamos ... Una vez aceptada la evolución transespecífica de los seres vivos, actualmente todos o casi todos aceptan el origen filogenético del cuerpo humano. Pero hay notables reticencias y hasta serias dificultades para aceptar ese mismo origen para el alma humana. Esas dificultades provienen tanto de un supuesto dogma acerca de la creación del alma directamente por Dios, como de posiciones metafísicas muy serias, entre las que cabe destacar la argumentación de Tomás de Aquino. El autor de este trabajo, dejando de lado el aspecto teológico -aunque señalando de paso su duda fundada respecto de la existencia de tal dogma creacionista- se enfrenta a los argumentos metafísicos, desde las mismas bases sistemáticas en que tales argumentos parecen fundarse. Su conclusión es que esos argumentos no son decisivos; y que, por tanto, se puede y se debe seguir buscando un origen filogenético común para el hombre en su totalidad, dejando de lado el dualismo antropológico accidentalista, de tipo platónico y racionalista.

  1. Estado nutricional y malaria en escolares de la comunidad de Santo Tomás en Iquitos, Perú

    Directory of Open Access Journals (Sweden)

    Javier Vargas H

    2003-10-01

    Full Text Available Se realizó un estudio piloto de seguimiento, durante 9 meses, a una cohorte de 52 niños escolares de Santo Tomás en Iquitos, Perú. El estado nutricional fue determinado al inicio y al final del estudio, así como la incidencia de malaria. Al inicio del estudio, 9,6% presentaron bajo peso para la edad, 32,7% baja talla para la edad, 61,9% presentaron bajos niveles de retinol sérico y 7,7% presentaron un Índice de Masa Corporal (IMC debajo del quinto percentil. Los indicadores no variaron significativamente en las mediciones iniciales y finales. La baja talla para la edad se asoció con la incidencia de malaria (RR 5,49, p=0,032. Podría ser un indicador de deficientes condiciones de vida, que a su vez, favorezcan la transmisión de la malaria.

  2. Changes in melatonin levels in transgenic 'Micro-Tom' tomato overexpressing ovine AANAT and ovine HIOMT genes.

    Science.gov (United States)

    Wang, Lin; Zhao, Yu; Reiter, Russel J; He, Changjiu; Liu, Guoshi; Lei, Qiong; Zuo, Bixiao; Zheng, Xiao Dong; Li, Qingtian; Kong, Jin

    2014-03-01

    In animals, the melatonin biosynthesis pathway has been well defined after the isolation and identification of the four key genes that are involved in the conversion of tryptophan to melatonin. In plants, there are special alternative catalyzing steps, and plant genes share very low homology with the animal genes. It was of interest to examine the phenotype of transgenic Micro-Tom tomato plants overexpressing the homologous sheep oAANAT and oHIOMT genes responsible for the last two steps of melatonin synthesis. The oAANAT transgenic plants have higher melatonin levels and lower indoleacetic acid (IAA) contents than control due to the competition for tryptophan, the same precursor for both melatonin and IAA. Therefore, the oAANAT lines lose the 'apical dominance' inferring that melatonin likely lacks auxin activity. The significantly higher melatonin content in oHIOMT lines than oAANAT lines provides new proof for the important role of ASMT in plant melatonin synthesis. In addition, the enhanced drought tolerance of oHIOMT lines will also be an important contribution for plant engineering. © 2013 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

  3. Can REDD+ help the conservation of restricted-range island species? Insights from the endemism hotspot of São Tomé

    DEFF Research Database (Denmark)

    de Lima, Ricardo Faustino; Olmos, Fábio; Dallimer, Martin

    2013-01-01

    values according to the OSIRIS database. These results show weaknesses of OSIRIS as a planning tool, and demonstrate that the benefits that REDD+ might bring for biodiversity are strongly dependent on its careful implementation. We recommend that payment for ecosystem services programmes such as REDD......REDD+ aims to offset greenhouse gas emissions through "Reduced Emissions from Deforestation and forest Degradation". Some authors suggest that REDD+ can bring additional benefits for biodiversity, namely for the conservation of extinction-prone restricted-range species. Here, we assess this claim...... that REDD+ could promote the loss of forests in São Tomé and Príncipe through leakage. This happened even when additional payments for biodiversity were included in the simulations, and despite São Tomé and Príncipe having the fourth highest carbon stocks per land area and the second highest biodiversity...

  4. Caracterização química do óleo de palma de São Tomé e Príncipe

    OpenAIRE

    Rodrigues, Nuno; Neto, Antónia Santos; Ramalhosa, Elsa; Casal, Susana; PEREIRA, J. de A.

    2014-01-01

    O óleo de palma, proveniente do fruto da palmeira do dendém, Elaeis guineensis Jacq., é um dos óleos vegetais mais consumidos e apreciados em São Tomé e Príncipe, sendo um ingrediente sempre presente nos pratos tradicionais. Neste sentido, com o presente trabalho pretendeu-se contribuir para a caraterização do óleo de palma extraído da palmeira do dendém, obtido de forma tradicional em São Tomé e Príncipe, no que respeita à sua composição química e resistência à oxidação. Para tal, recolheram...

  5. Bivariate genome-wide association meta-analysis of pediatric musculoskeletal traits reveals pleiotropic effects at the SREBF1/TOM1L2 locus

    DEFF Research Database (Denmark)

    Medina-Gomez, Carolina; Kemp, John P; Dimou, Niki L

    2017-01-01

    bone mineral density loci: WNT4, GALNT3, MEPE, CPED1/WNT16, TNFSF11, RIN3, and PPP6R3/LRP5. Variants in the TOM1L2/SREBF1 locus exert opposing effects TB-LM and TBLH-BMD, and have a stronger association with the former trait. We show that SREBF1 is expressed in murine and human osteoblasts, as well...

  6. Optimisation of tomato Micro-tom regeneration and selection on glufosinate/Basta and dependency of gene silencing on transgene copy number.

    Science.gov (United States)

    Khuong, Thi Thu Huong; Crété, Patrice; Robaglia, Christophe; Caffarri, Stefano

    2013-09-01

    An efficient protocol of transformation and selection of transgenic lines of Micro-tom, a widespread model cultivar for tomato, is reported. RNA interference silencing efficiency and stability have been investigated and correlated with the number of insertions. Given its small size and ease of cultivation, the tomato (Solanum lycopersicon) cultivar Micro-tom is of widespread use as a model tomato plant. To create and screen transgenic plants, different selectable markers are commonly used. The bar marker carrying the resistance to the herbicide glufosinate/Basta, has many advantages, but it has been little utilised and with low efficiency for identification of tomato transgenic plants. Here we describe a procedure for accurate selection of transgenic Micro-tom both in vitro and in soil. Immunoblot, Southern blot and phenotypic analyses showed that 100 % of herbicide-resistant plants were transgenic. In addition, regeneration improvement has been obtained by using 2 mg/l Gibberellic acid in the shoot elongation medium; rooting optimisation on medium containing 1 mg/l IAA allowed up to 97 % of shoots developing strong and very healthy roots after only 10 days. Stable transformation frequency by infection of leaf explants with Agrobacterium reached 12 %. Shoots have been induced by combination of 1 mg/l zeatin-trans and 0.1 mg/l IAA. Somatic embryogenesis of cotyledon on medium containing 1 mg/l zeatin + 2 mg/l IAA is described in Micro-tom. The photosynthetic psbS gene has been used as reporter gene for RNA silencing studies. The efficiency of gene silencing has been found equivalent using three different target gene fragments of 519, 398 and 328 bp. Interestingly, silencing efficiency decreased from T0 to the T3 generation in plants containing multiple copies of the inserted T-DNA, while it was stable in plants containing a single insertion.

  7. Translocation of connexin 43 to the inner mitochondrial membrane of cardiomyocytes through the heat shock protein 90-dependent TOM pathway and its importance for cardioprotection.

    Science.gov (United States)

    Rodriguez-Sinovas, Antonio; Boengler, Kerstin; Cabestrero, Alberto; Gres, Petra; Morente, Miriam; Ruiz-Meana, Marisol; Konietzka, Ina; Miró, Elisabet; Totzeck, Andreas; Heusch, Gerd; Schulz, Rainer; Garcia-Dorado, David

    2006-07-07

    We have previously shown that connexin 43 (Cx43) is present in mitochondria, that its genetic depletion abolishes the protection of ischemia- and diazoxide-induced preconditioning, and that it is involved in reactive oxygen species (ROS) formation in response to diazoxide. Here we investigated the intramitochondrial localization of Cx43, the mechanism of Cx43 translocation to mitochondria and the effect of inhibiting translocation on the protection of preconditioning. Confocal microscopy of mitochondria devoid of the outer membrane and Western blotting on fractionated mitochondria showed that Cx43 is located at the inner mitochondrial membrane, and coimmunoprecipitation of Cx43 with Tom20 (Translocase of the outer membrane 20) and with heat shock protein 90 (Hsp90) indicated that it interacts with the regular mitochondrial protein import machinery. In isolated rat hearts, geldanamycin, a blocker of Hsp90-dependent translocation of proteins to the inner mitochondrial membrane through the TOM pathway, rapidly (15 minutes) reduced mitochondrial Cx43 content by approximately one-third in the absence or presence of diazoxide. Geldanamycin alone had no effect on infarct size, but it ablated the protection against infarction afforded by diazoxide. Geldanamycin abolished the 2-fold increase in mitochondrial Cx43 induced by 2 preconditioning cycles of ischemia/reperfusion, but this effect was not associated with reduced protection. These results demonstrate that Cx43 is transported to the inner mitochondrial membrane through translocation via the TOM complex and that a normal mitochondrial Cx43 content is important for the diazoxide-related pathway of preconditioning.

  8. Enhancement of phytosterols, taraxasterol and induction of extracellular pathogenesis-related proteins in cell cultures of Solanum lycopersicum cv Micro-Tom elicited with cyclodextrins and methyl jasmonate.

    Science.gov (United States)

    Briceño, Zuleika; Almagro, Lorena; Sabater-Jara, Ana B; Calderón, Antonio A; Pedreño, María Angeles; Ferrer, María Angeles

    2012-07-15

    Suspension-cultured cells of Solanum lycopersicum cv Micro-Tom were used to evaluate the effect of methyl jasmonate and cyclodextrins, separately or in combination, on the induction of defense responses. An extracellular accumulation of two sterols (isofucosterol and β-sitosterol) and taraxasterol, a common tomato fruit cuticular triterpene, were observed. Their levels were higher in Micro-Tom tomato suspension cultured cells elicited with cyclodextrins than in control and methyl jasmonate-treated cells. Also, their accumulation profiles during the cell growth phase were markedly different. The most striking feature in response to cyclodextrin treatments was the observed enhancement of taraxasterol accumulation. Likewise, the exogenous application of methyl jasmonate and cyclodextrins induced the accumulation of pathogenesis-related proteins. Analysis of the extracellular proteome showed the presence of amino acid sequences homologous to pathogenesis-related 1 and 5 proteins, a cationic peroxidase and a biotic cell death-associated protein, which suggests that methyl jasmonate and cyclodextrins could play a role in mediating defense-related gene product expression in S. lycopersicum cv Micro-Tom. Copyright © 2012 Elsevier GmbH. All rights reserved.

  9. Tom Tabor, the owner of Tabor Communications, presents Wolfgang von Rüden with the Editors Choice Award of HPCwire, which was awarded to CERN for its commitment to educating the public about high-performance computing.

    CERN Multimedia

    Maximilien Brice

    2006-01-01

    Tom Tabor, the owner of Tabor Communications, presents Wolfgang von Rüden with the Editors Choice Award of HPCwire, which was awarded to CERN for its commitment to educating the public about high-performance computing.

  10. Comparison between OMI-TOMS and OMI-DOAS Ozone Columns over High SO2 regions: Volcanic and Chinese Industrial Region

    Science.gov (United States)

    Choi, Wonei; Hong, Hyunkee; Lee, Hanlim

    2017-04-01

    In this present study, we identified the SO2 effect on O3 retrieval from the Ozone Monitoring Instrument (OMI) measurement. The difference between OMI-Total Ozone Mapping Spectrometer (TOMS) and OMI-Differential Optical Absorption Spectrometer (DOAS) total O3 is calculated in high SO2 volcanic regions (Anatahan, La Cumbre, Sierra Negra, and Piton) and Chinese industrial region from 2005 through 2008. In volcanic plumes, OMI-TOMS total O3 column increases with middle and upper troposphere and stratosphere (TRM-STL) SO2, showing high correlation (R = 0.54) between TRM-STL SO2 and TOMS O3 while there is negligible correlation (R = 0.11) between TRM-STL SO2 and OMI- DOAS O3. There is a certain correlation (R = 0.54) between TRM-STL SO2 and the difference between OMI-TOMS and OMI-DOAS O3 (T-D). The T-D reaches its maximum up to 90 DU. T-D has a dependence on planetary boundary layer (PBL) SO2 (R = 0.36) even though T-D in the Chinese industrial region increases more slowly with SO2 than at the volcanic sites. Thus, the altitude at which SO2 exists has an effect on T-D, which could be due to reduced absolute radiance sensitivity in the boundary layer at 317.5 nm (the wavelength used to retrieve OMI-TOMS ozone in boundary layer). In addition, T-D shows a seasonal tendency on PBL SO2. In Turkey and Western USA, where PBL SO2 concentrations are low, |T-D| shows its positive maximum in summer and negative maximum in winter. However, no seasonal variation of T-D was found in the Chinese industrial region due to the effect of low and high PBL SO2 in summer and winter, respectively. The reason for the seasonal characteristics of T-D in the Chinese industrial region will be discussed.

  11. Large-scale analysis of full-length cDNAs from the tomato (Solanum lycopersicum) cultivar Micro-Tom, a reference system for the Solanaceae genomics.

    Science.gov (United States)

    Aoki, Koh; Yano, Kentaro; Suzuki, Ayako; Kawamura, Shingo; Sakurai, Nozomu; Suda, Kunihiro; Kurabayashi, Atsushi; Suzuki, Tatsuya; Tsugane, Taneaki; Watanabe, Manabu; Ooga, Kazuhide; Torii, Maiko; Narita, Takanori; Shin-I, Tadasu; Kohara, Yuji; Yamamoto, Naoki; Takahashi, Hideki; Watanabe, Yuichiro; Egusa, Mayumi; Kodama, Motoichiro; Ichinose, Yuki; Kikuchi, Mari; Fukushima, Sumire; Okabe, Akiko; Arie, Tsutomu; Sato, Yuko; Yazawa, Katsumi; Satoh, Shinobu; Omura, Toshikazu; Ezura, Hiroshi; Shibata, Daisuke

    2010-03-30

    The Solanaceae family includes several economically important vegetable crops. The tomato (Solanum lycopersicum) is regarded as a model plant of the Solanaceae family. Recently, a number of tomato resources have been developed in parallel with the ongoing tomato genome sequencing project. In particular, a miniature cultivar, Micro-Tom, is regarded as a model system in tomato genomics, and a number of genomics resources in the Micro-Tom-background, such as ESTs and mutagenized lines, have been established by an international alliance. To accelerate the progress in tomato genomics, we developed a collection of fully-sequenced 13,227 Micro-Tom full-length cDNAs. By checking redundant sequences, coding sequences, and chimeric sequences, a set of 11,502 non-redundant full-length cDNAs (nrFLcDNAs) was generated. Analysis of untranslated regions demonstrated that tomato has longer 5'- and 3'-untranslated regions than most other plants but rice. Classification of functions of proteins predicted from the coding sequences demonstrated that nrFLcDNAs covered a broad range of functions. A comparison of nrFLcDNAs with genes of sixteen plants facilitated the identification of tomato genes that are not found in other plants, most of which did not have known protein domains. Mapping of the nrFLcDNAs onto currently available tomato genome sequences facilitated prediction of exon-intron structure. Introns of tomato genes were longer than those of Arabidopsis and rice. According to a comparison of exon sequences between the nrFLcDNAs and the tomato genome sequences, the frequency of nucleotide mismatch in exons between Micro-Tom and the genome-sequencing cultivar (Heinz 1706) was estimated to be 0.061%. The collection of Micro-Tom nrFLcDNAs generated in this study will serve as a valuable genomic tool for plant biologists to bridge the gap between basic and applied studies. The nrFLcDNA sequences will help annotation of the tomato whole-genome sequence and aid in tomato functional

  12. A base sócio-histórica na construção do protagonista em As Aventuras de Tom Sawyer

    Directory of Open Access Journals (Sweden)

    Ângela Tavares Nates Moreira

    2015-06-01

    Full Text Available A obra The Adventures of Tom Sawyer, escrita pelo autor norte americano Samuel Langhorne Clemens, mais conhecido pelo pseudônimo Mark Twain, é considerada, hoje, a narrativa que inaugurou a literatura infanto-juvenil, no século XIX. Essa narrativa ganha maior expressividade devido a sua escrita de caráter regionalista utilizado pelo autor. Com a publicação de As Aventuras de Tom Sawyer, Mark Twain percorre o ambiente literário, com traços marcados pelo humor, pelo Realismo e pelo Regionalismo. Este trabalho objetiva analisar os fragmentos da fala de Tom e aspectos sócio-históricos de uma época de mudanças.  A finalidade é considerar o processo de transição do protagonista, dentro do romance. Desse modo, foram selecionados alguns fragmentos que revelam pontos Realistas. Após a leitura da obra, foram verificados e extraídos fragmentos representativos do jovem protagonista, tais como crenças religiosas, compreensão de mundo e valores morais. O filtro analítico se pauta no trabalho de teóricos como Bakhtin (2010, Watt (2010 e Blair (1967, entre outros, que contribuíram com informações sobre o desenvolvimento político, cultural e religioso das famílias americanas do Centro-Oeste dos Estados Unidos do século XIX. Serão abordadas as teorias sobre o personagem, a partir das reflexões de Gancho (2006 e Candido (2007. Os vários fragmentos analisados permitiram-nos chegar à conclusão sobre o modo como a transição do jovem protagonista foi influenciada, quais as características que revelam suas preferências e opiniões, e, por acréscimo, verificar que muitas dessas respostas poderão ser constatadas em conformidade com o período da época que, “irrevogavelmente”, são considerados intrínsecos na vida de Tom Sawyer.Palavras-chave: protagonista; regionalismo; realismo; Tom Sawyer.

  13. Population Genetics of the São Tomé Caecilian (Gymnophiona: Dermophiidae: Schistometopum thomense) Reveals Strong Geographic Structuring

    Science.gov (United States)

    Stoelting, Ricka E.; Measey, G. John; Drewes, Robert C.

    2014-01-01

    Islands provide exciting opportunities for exploring ecological and evolutionary mechanisms. The oceanic island of São Tomé in the Gulf of Guinea exhibits high diversity of fauna including the endemic caecilian amphibian, Schistometopum thomense. Variation in pigmentation, morphology and size of this taxon over its c. 45 km island range is extreme, motivating a number of taxonomic, ecological, and evolutionary hypotheses to explain the observed diversity. We conducted a population genetic study of S. thomense using partial sequences of two mitochondrial DNA genes (ND4 and 16S), together with morphological examination, to address competing hypotheses of taxonomic or clinal variation. Using Bayesian phylogenetic analysis and Spatial Analysis of Molecular Variance, we found evidence of four geographic clades, whose range and approximated age (c. 253 Kya – 27 Kya) are consistent with the spread and age of recent volcanic flows. These clades explained 90% of variation in ND4 (φCT = 0.892), and diverged by 4.3% minimum pairwise distance at the deepest node. Most notably, using Mismatch Distributions and Mantel Tests, we identified a zone of population admixture that dissected the island. In the northern clade, we found evidence of recent population expansion (Fu's Fs = −13.08 and Tajima's D = −1.80) and limited dispersal (Mantel correlation coefficient = 0.36, p = 0.01). Color assignment to clades was not absolute. Paired with multinomial regression of chromatic data, our analyses suggested that the genetic groups and a latitudinal gradient together describe variation in color of S. thomense. We propose that volcanism and limited dispersal ability are the likely proximal causes of the observed genetic structure. This is the first population genetic study of any caecilian and demonstrates that these animals have deep genetic divisions over very small areas in accordance with previous speculations of low dispersal abilities. PMID:25171066

  14. Evaluating Ultraviolet Radiation Exposures Determined from TOMS Satellite Data at Sites of Amphibian Declines in Central and South America

    Science.gov (United States)

    Middleton, Elizabeth M.; Smith, David E. (Technical Monitor)

    2000-01-01

    Many amphibian species have experienced substantial population declines, or have disappeared altogether, during the last several decades at a number of amphibian census sites in Central and South America. This study addresses the use of satellite-derived trends in solar ultraviolet-B (UV-B; 280-320 nm) radiation exposures at these sites over the last two decades, and is intended to demonstrate a role for satellite observations in determining whether UV-B radiation is a contributing factor in amphibian declines. UV-B radiation levels at the Earth's surface were derived from the Total Ozone Mapping Spectrometer (TOMS) satellite data, typically acquired daily since 1979. These data were used to calculate the daily erythemal (sunburning) UV-B, or UV-B(sub ery), exposures at the latitude, longitude, and elevation of each of 20 census sites. The annually averaged UV-B(sub ery) dose, as well as the maximum values, have been increasing in both Central and South America, with higher levels received at the Central American sites. The annually averaged UV-B(sub ery) exposures increased significantly from 1979-1998 at all 11 Central American sites examined (r(exp 2) = 0.60 - 0.79; Pexposure levels (>= 6750 J/sq m*d) to the annual UV-B(sub ery) total has increased from approx. 5% to approx. 15% in Central America over the 19 year period, but actual daily exposures for each species are unknown. Synergy among UV-B radiation and other factors, especially those associated with alterations of water chemistry (e.g., acidification) in aqueous habitats is discussed. These findings justify further research concerning whether UV-B(sub ery) radiation plays a role in amphibian population declines and extinctions.

  15. Synoptic study of the seasonal variability of dust cases observed by the TOMS satellite over northern Saudi Arabia

    Science.gov (United States)

    Awad, Adel M.; Mashat, Abdul-Wahab S.; Alamoudi, Ahmad O.; Assiri, Mazen E.

    2016-05-01

    The aerosol index (AI) from the Total Ozone Mapping Spectrometer (TOMS) satellite and meteorological parameters from National Center for Environmental Prediction and the National Center for Atmospheric Research (NCEP/NCAR) reanalysis datasets were used to examine seasonal dust cases in northern Saudi Arabia. Considering all seasons, winter has the fewest dust cases, whereas summer has the most dust cases. Synoptically, surface high-pressure systems in the eastern and western regions are important for the occurrence of dust cases over the northern Arabian Peninsula. When the eastern high pressure prevails, the effects of the Indian low-pressure system on the Arabian Peninsula are weakened or become nonexistent. The extension of the western high-pressure system toward the southeast provides an opportunity for a low-pressure system over Southeast Africa to connect with the Indian low-pressure system, which increases the width of the low-pressure trough and affects the Arabian Peninsula by increasing the amount of dust over the region. At 850 hPa, the weather systems typically rotate clockwise between winter and autumn. In winter, cyclonic systems prevail in the northern region, while anticyclonic systems prevail in the south. The systems are oriented toward the northeast in spring, the west in summer, and the southeast in autumn. Moreover, northern cyclones at 500 hPa shrink as they move northward and the maximum wind speed at 250 hPa decreases from winter to summer. Furthermore, the case study confirms that a change in the relative strength of the pressure systems and a change in the orientation of the isobars (contours) affect the amount of dust over the area. When the orientation of the isobar (contour) lines become strictly north to south or east to west, the amount of dust decreases and vice versa.

  16. Sotsiaalne indekseerimine / Tom Simonite

    Index Scriptorium Estoniae

    Simonite, Tom

    2011-01-01

    Veebiteenuste, eriti isikute Facebook'ides kajastatu taaskaardistamine võimaldab kogutud infot analüüsides kliendile edaspidi pakkuda täpsemat ja õigemat valikut eeldatavalt klienti huvitatavatest teenustest

  17. Trouble in Toms River

    Science.gov (United States)

    Lugg, Catherine A.; Tooms, Autumn K.

    2011-01-01

    Drawing on a recent New Jersey Supreme Court decision (2007), this case addresses a school district's responsibility regarding homophobic bullying, school culture, and the rights of lesbian, gay, bisexual, and transgender students to be free of discrimination.

  18. Skandaal kunstimaailmas / Tom Rhodes

    Index Scriptorium Estoniae

    Rhodes, Tom

    2000-01-01

    Kriis Sotheby'se ja Christie'se oksjonimajades, mille põhjustasid Christie'se endise tegevjuhi Chris Davidge märkmed, mis kinnitavad oksjonimajade vahel toimunud väidetavaid kokkuleppeid hinnapoliitikas. 23. II astusid tagasi tegevjuhid Alfred Taubman ja Diana Brooks. Uus tegevjuht Michael Soverni, president William Ruprecht.

  19. Videnskabsretorik eller tom retorik

    DEFF Research Database (Denmark)

    Jensen, Leif Becker

    2005-01-01

    Artiklen omhandler videnskabsretorik såvel i den videnskabelige undersøgelse som i fremlæggelsen inden for forskellige paradigmer, herunder argumetnation set i lyset af Toulmins argumentationsmodel....

  20. Determination of the UV solar risk in Argentina with high-resolution maps calculated using TOMS ozone climatology

    Science.gov (United States)

    Piacentini, Rubén D.; Cede, Alexander; Luccini, Eduardo; Stengel, Fernando

    2004-01-01

    The connection between ultraviolet (UV) radiation and various skin diseases is well known. In this work, we present the computer program "UVARG", developed in order to prevent the risk of getting sunburn for persons exposed to solar UV radiation in Argentina, a country that extends from low (tropical) to high southern hemisphere latitudes. The software calculates the so-called "erythemal irradiance", i.e., the spectral irradiance weighted by the McKinlay and Diffey action spectrum for erythema and integrated in wavelength. The erythemal irradiance depends mainly on the following geophysical parameters: solar elevation, total ozone column, surface altitude, surface albedo, total aerosol optical depth and Sun-Earth distance. Minor corrections are due to the variability in the vertical ozone, aerosol, pressure, humidity and temperature profiles and the extraterrestrial spectral solar UV irradiance. Key parameter in the software is a total ozone column climatology incorporating monthly averages, standard deviations and tendencies for the particular geographical situation of Argentina that was obtained from TOMS/NASA satellite data from 1978 to 2000. Different skin types are considered in order to determine the sunburn risk at any time of the day and any day of the year, with and without sunscreen protection. We present examples of the software for three different regions: the high altitude tropical Puna of Atacama desert in the North-West, Tierra del Fuego in the South when the ozone hole event overpasses and low summertime ozone conditions over Buenos Aires, the largest populated city in the country. In particular, we analyzed the maximum time for persons having different skin types during representative days of the year (southern hemisphere equinoxes and solstices). This work was made possible by the collaboration between the Argentine Skin Cancer Foundation, the Institute of Physics Rosario (CONICET-National University of Rosario, Argentina) and the Institute of

  1. La Chartreuse de Parme,Tom Jones et Vanity Fair : la représentation autoconsciente dans trois stades de développement

    OpenAIRE

    Vågslid, Gudfrid

    2007-01-01

    En résumé INTRODUCTION Pour ce mémoire j ai choisi trois uvres réalistes, notamment The History of Tom Jones, a Foundling publié par Henry Fielding en 1749, La Chartreuse de Parme de Stendhal (1839) et Vanity Fair, a novel without a hero de William Makepeace Thackeray qui est paru en feuilleton en 1847-48. Je me concentrerai sur la Chartreuse et me servirai d exemples des deux autres uvres pour mettre en relief celle de Stendhal. Stendhal et Fielding partageaient « le m...

  2. La iglesia de los santos Ildefonso y Tomás de Villanueva en Roma: un monumento barroco a la pietas hispanica

    Directory of Open Access Journals (Sweden)

    González Tornel, Pablo

    2015-03-01

    Full Text Available In 1667 the construction of the Hospice of Saints Ildefonso and Tomás de Villanueva began on the Roman Via Sistina. The headquarters of the Augustinian Recollects in Rome took on a particular architectural configuration directly inspired by Francesco Borromini’s Chapel of the Three Kings and a very concrete iconography linked to the political situation during the second half of the 17th century. Thus the church was decorated to create a monument to the Immaculate Conception with images of the Loreto litany adorning its walls, reinforced by paintings of the Virgins of Copacabana and Guadalupe inside. All of this, combined with the dedication of the building to Saint Tomás de Villanueva (canonized in 1658, turns the temple into a celebration of the pietas hispanica in an area of the Holy City scene of clashes for power between France and Spain.En 1667 se pone la primera piedra del Hospicio de los santos Ildefonso y Tomás de Villanueva en la Via Sistina romana. La sede de la orden de los agustinos recoletos en Roma toma una particular configuración arquitectónica, directamente inspirada en la Capilla de los Reyes Magos de Francesco Borromini, y una muy definida iconografía vinculada con la situación política de la segunda mitad del siglo XVII. Así, la iglesia se erige en un monumento a la Inmaculada Concepción concretado en las imágenes de la letanía lauretana que ornan sus muros y reforzado por las pinturas de las vírgenes de Copacabana y Guadalupe en su interior. Todo ello, junto a la advocación a Santo Tomás de Villanueva, canonizado en 1658, convierte el templo en un alegato a la pietas hispanica en un área de la ciudad que fue escenario de los enfrentamientos entre Francia y España.

  3. Can REDD+ help the conservation of restricted-range island species? Insights from the endemism hotspot of São Tomé

    DEFF Research Database (Denmark)

    de Lima, Ricardo Faustino; Olmos, Fábio; Dallimer, Martin;

    2013-01-01

    REDD+ aims to offset greenhouse gas emissions through "Reduced Emissions from Deforestation and forest Degradation". Some authors suggest that REDD+ can bring additional benefits for biodiversity, namely for the conservation of extinction-prone restricted-range species. Here, we assess this claim...... and abundance of endemic species, supporting the potential of REDD+ to protect these taxa. We then assessed if REDD+ could help protect the forests of São Tomé and Príncipe. To do so, we used OSIRIS simulations to predict country-level deforestation under two different REDD+ designs. These simulations showed...

  4. 6 June 2008 - Chancellor F. Tomàs Vert, University of Valencia, visiting ATLAS control room and experimental area with Collaboration Spokesperson P. Jenni.

    CERN Multimedia

    Mona Schweizer

    2008-01-01

    6 June 2008 - Chancellor F. Tomàs Vert, University of Valencia, visiting ATLAS control room and experimental area with Collaboration Spokesperson P. Jenni. Other participants: Prof. Francisco José Botella, Director, Instituto de Fisica Corpuscular, University of València and CSIC Prof. José Peñarrocha, Dean, Faculty of Physics Prof. Antonio Ferrer, Instituto de Fisica Corpuscular, University of València and CSIC Prof. Antonio Pich, University of València, Member of IFIC (CSIC - Univ. València), Coordinator of CPAN, Spanish National Centre for Particle, Astroparticle and Nuclear Physics.

  5. World-class Prescription for Quality by Tom Peters%汤姆·彼得斯的"世界级质量药方"

    Institute of Scientific and Technical Information of China (English)

    木易

    2004-01-01

    @@ 当代最富创新精神的管理思想家汤姆·彼得斯(Tom Peters)在其名著(Thrivingon Chaos Handbook for a Management Revolution)中用"压倒一切的质量问题"、"长期被忽视的事实:质量等于利润"、"质量必须用客户的感觉来评价"等语句来描述对质量现状的诊断,并开出了他的处方:发动一场质量革命!

  6. ¡Bernabé, Bernabé! de Tomás de Mattos : Crisis y revisión de la identidad uruguaya

    OpenAIRE

    Basile, Teresa

    1996-01-01

    El auge de la novela histórica en Uruguay parece marcar una de las líneas preponderantes en el campo literario de la postdictadura iniciada en 1985. Varias de estas novelas históricas eligen volver a los sucesos más sombríos y sangrientos de la historia del conflictivo siglo XIX: el etnocidio charrúa, las guerras civiles entre las divisas, el militarismo de Latorre, la Guerra de la Triple Alianza. ¡Bernabé, Bernabé!, (1988) de Tomás de Mattos, El príncipe de la muerte (1993) de Fernando Butaz...

  7. HIV-1 infection, response to treatment and establishment of viral latency in a novel humanized T cell-only mouse (TOM) model.

    Science.gov (United States)

    Honeycutt, Jenna B; Wahl, Angela; Archin, Nancie; Choudhary, Shailesh; Margolis, David; Garcia, J Victor

    2013-10-24

    The major targets of HIV infection in humans are CD4⁺ T cells. CD4⁺ T cell depletion is a hallmark of AIDS. Previously, the SCID-hu thy/liv model was used to study the effect of HIV on thymopoeisis in vivo. However, these mice did not develop high levels of peripheral T cell reconstitution and required invasive surgery for infection and analysis. Here, we describe a novel variant of this model in which thy/liv implantation results in systemic reconstitution with human T cells in the absence of any other human hematopoietic lineages. NOD/SCID-hu thy/liv and NSG-hu thy/liv mice were created by implanting human fetal thymus and liver tissues under the kidney capsule of either NOD/SCID or NSG mice. In contrast to NOD/SCID-hu thy/liv mice that show little or no human cells in peripheral blood or tissues, substantial systemic human reconstitution occurs in NSG-hu thy/liv. These mice are exclusively reconstituted with human T cells (i.e. T-cell only mice or TOM). Despite substantial levels of human T cells no signs of graft-versus-host disease (GVHD) were noted in these mice over a period of 14 months. TOM are readily infected after parenteral exposure to HIV-1. HIV replication is sustained in peripheral blood at high levels and results in modest reduction of CD4⁺ T cells. HIV-1 replication in TOM responds to daily administration of combination antiretroviral therapy (ART) resulting in strong suppression of virus replication as determined by undetectable viral load in plasma. Latently HIV infected resting CD4⁺ T cells can be isolated from suppressed mice that can be induced to express HIV ex-vivo upon activation demonstrating the establishment of latency in vivo. NSG-hu thy/liv mice are systemically reconstituted with human T cells. No other human lymphoid lineages are present in these mice (i.e. monocytes/macrophages, B cells and DC are all absent). These T cell only mice do not develop GVHD, are susceptible to HIV-1 infection and can efficiently maintain virus

  8. Cambio climático, educación ambiental e turismo: unha reflexión para o futuro de São Tomé

    OpenAIRE

    2009-01-01

    Para min é un pracer moi grande estar en São Tomé e Príncipe e participar neste foro. conferencia. É tamén, e sobre todo, a oportunidade de vivir e compartir unha gran experiencia. Xa levo por estes lugares cerca de dúas semanas, e conforme fun coñecendo as circunstancias do país e as súas xentes, e despois de ollar tamén o conxunto das comunicacións que se presentan ao Seminario, pensei que podía ser interesante facer unha pequena mudanza, ou grande, conforme se mire, na orien...

  9. Lugar común la muerte, de Tomás Eloy Martínez: una invención a manera de la realidad Tomás Eloy Martínez's Lugar común la muerte: Invention as Reality

    Directory of Open Access Journals (Sweden)

    Marcelo Coddou

    2010-07-01

    Full Text Available Este ensayo intenta estudiar la índole de periodismo narrativo que constituyen las crónicas que conforman el libro Lugar común la muerte del escritor argentino Tomás Eloy Martínez (1934-2010. Se discute la oposición verdad/documento vs. verosimilitud/imaginación, para mostrar cómo los escritos periodísticos de este libro se inscriben en una modalidad genérica que, habiendo nacido en América Latina durante la vigencia del Modernismo, ha continuado dando muestras notables hasta nuestros días. Se analizan algunas de las estrategias narrativas que el periodista Tomás Eloy Martínez empleara en textos que, publicados originalmente en diarios de Caracas y Buenos Aires, fueron leídos como tales, como escritos periodísticos. Para ello se revisan cuidadosamente algunos de los principales postulados teóricos que formulara al respecto el propio escritor-periodista autor del libro aquí considerado.The following essay will present an analysis of creative nonfiction from the chronicles gathered in Lugar común la muerte written by Argentinean writer Tomás Eloy Martínez (1934 - 2010. The essay will discuss the opposition between truth/document versus credibility/imagination, so as to portray how journalistic writing is inscribed in a generic form that was conceived under the rules of Latin-American Modernism; form that still prevails until nowadays. The essay will also discuss the narrative strategies that Tomás Eloy Martínez uses in the texts that were originally published in newspapers of Caracas and Buenos Aires, and that were read merely as journalistic pieces of writing. For this reason, the essay will carefully revise some of the main theoretical postulates that were written by the very same writer/journalist.

  10. Scapegoating Non-Conforming Identities: Witchcraft Hysteria in Arthur Miller’s The Crucible and Caryl Churchill’s Vinegar Tom

    Directory of Open Access Journals (Sweden)

    Neslihan Yılmaz Demirkaya

    2015-12-01

    Full Text Available Scapegoating Non-Conforming Identities: Witchcraft Hysteria in Arthur Miller’s The Crucible and Caryl Churchill’s Vinegar Tom Abstract When people are faced with different takes on their traditions that they firmly cling to so as to remain being who they purport to be, they are generally inclined to ostracise those who are different. In this sense, ostracising people by discarding them from their community is, metaphorically speaking, the same as leaving the goat in the wilderness as the verses from Leviticus explain the history of scapegoating. Just as the goat story from Leviticus, political and patriarchal power groups blame non-conforming individuals for all the problems in society, and ostracise them as witches only to take the upper hand, and enjoy absolute power. The pattern of punishment proves to be the same, that is, to leave the victim alone in a place away from home, be it the wilderness for a goat, or the loneliness and isolation for an individual. Besides, one of the most used and most efficient ways of scapegoating people, as the evidence shows, is to rekindle the tall-tale of witchcraft. This paper explores how and why witchcraft is deployed as a scapegoating strategy to silence and stigmatise non-conforming individuals on the pretext of maintaining order in society in Arthur Miler’s The Crucible (1953 and Caryl Churchill’s Vinegar Tom (1976 respectively.

  11. LAS POÉTICAS (NEOBARROCAS DE DIEGO MAQUIEIRA Y TOMÁS HARRIS Diego Maquieira and Tomás Harris in (neobaroque code

    Directory of Open Access Journals (Sweden)

    Oscar Galindo V

    2010-12-01

    Full Text Available Este artículo analiza dos textos fundamentales de la poesía chilena de los años 80: Tiranade Diego Maquieira y Cipango de Tomás Harris en clave (neobarroca, para advertir la resignificación de algunas de sus problemáticas más representativas. Se trata de textos que ponen en tensión la idea de representación por medio del travestimiento, el disfraz barroco, en el primer caso, y el engaño de los sentidos, en el segundo, en el contexto de una discusión sobre la temporalidad histórica y el autoritarismo.This article explores two fundamental texts of Chilean poetry of the 80s: Diego Maquieira´s La Tirana and Tomás Harris´s Cipango in (neobaroque code, to suggest the redefinition of some of their most representative problematics. These are texts that stress the idea of representation by means of cross-dressing, the baroque costume in the first case, and the deceitfulness of the senses in the second, in the context of a discussion of historical temporality and authoritarianism.

  12. Effect of deslorelin on testicular function, serum dihydrotestosterone and oestradiol concentrations during and after suppression of sexual activity in tom cats.

    Science.gov (United States)

    Gültiken, Nilgün; Aslan, Selim; Ay, Serhan Serhat; Gülbahar, Mustafa Yavuz; Thuróczy, Julianna; Koldaş, Ece; Kaya, Duygu; Fındık, Murat; Schäfer-Somi, Sabine

    2017-02-01

    Objectives The aim of the study was to evaluate the efficacy of a 4.7 mg deslorelin implant in tom cats. Methods Nine mature male cats were included in the deslorelin group and five cats in the control group. Before the study started, all cats were confirmed to have distinct sexually dimorphic behaviour. Blood samples were taken on the implantation day, at day 7 and at day 15, then monthly, in order to measure serum dihydrotestosterone (DHT) and 17beta(β)-oestradiol concentrations. The deslorelin group (n = 9) was divided into two subgroups: five cats (cats 1-5) were neutered in the postimplantation period during suppression of sexually dimorphic behaviour, and four cats (cats 6-9) were neutered after re-expression of sexually dimorphic behaviour. The control group cats (n = 5) were castrated without administration of the implant. Results Sexually dimorphic behaviours ceased within a mean ± SD of 13-58 days (23.30 ± 14.17) after implantation. DHT concentration decreased within 30 days. The mean duration of suppression was 26.5 ± 7.42 months and reactivation coincided with increased DHT values reaching preimplantation concentrations within 1 month. 17β-oestradiol concentrations significantly correlated with DHT concentrations ( P tom cats without any side effects and with full reversibility; however, duration of suppression is highly individual.

  13. Relaciones entre masculinidades: Controversia en La cabaña del tío Tom Relations among Masculinities: Controversy in Uncle Tom’s Cabin

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    Luis Fernando Gómez R.

    2007-01-01

    Full Text Available The American novel Uncle Tom’s Cabin, written by Harriet Beecher-Stowe, has caused historical debate because of its notion of masculinity between white men and African-American slaves in the antebellum period. The description of these two antagonist forces are said to be defined by the author on extreme foundations of sentimentalist and romantic racialism that seem to distort the real objective events related to slavery in America . Beecher-Stowe was condemned by both white and black races because of the denunciation she makes of slavery as a hegemonic male institution. This article examines this polemic in Uncle Tom’s cabin, based on the sociologist R.W. Connell’s theory of relations among masculinities. From this theory, the article argues that while whites’ masculinity is determined by a sense of power based on hegemony, complicity, and subordination, blacks’, represented by uncle Tom, is portrayed as adopting weak submission and resigned marginalization. As Uncle Tom’s Cabin is the inspiration of a historical reality, this article also studies the novel in relation to factual events in which the ideals of hegemonic masculinity established slavery as a powerful institution in America .La cabaña del tío Tom, escrita por Beecher-Stowe ha causado debate histórico debido a su noción de masculinidad entre el hombre blanco y el hombre africano durante el período de la esclavitud. Se dice que la autora describe estas dos fuerzas antagónicas con fundamentos extremos de sentimentalismo y romanticismo racial, que parecen distorsionar los hechos reales relacionados con la esclavitud en Estados Unidos. Ambas razas condenaron a la novelista por la denuncia que hace de la esclavitud como una institución hegemónicamente masculina. En este artículo se examina tal polémica en La cabaña del tío Tom, a la luz de la teoría que propone el sociólogo R.W. Connell sobre relaciones entre masculinidades. A partir de ésta, se argumenta el

  14. Edith Stein y Tomás de Aquino: repercusión sobre la cuestión de la mujer

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    Anneliese Meis

    2010-01-01

    Full Text Available teniendo en cuenta el trasfondo esbozado y siempre de nuevo actualizado por Hanna-Barbara Gerl-Falkovitz, el presente estudio elabora una breve respuesta a la pregunta por la relación de Edith Stein con Tomás de Aquino a la luz de un escueto análisis de Endliches und Ewiges Sein VII, 1-2, contextualizado a través de los ejes centrales de la obra magna steiniana. Este análisis permite apreciar la semejanza desemejante de la comprensión de Edith Stein en relación con Tomás de Aquino a partir de un aspecto clave de la argumentación tomaseana, es decir, aquella que se basa en la STh I q.29, De personas divinas. El abordaje de este texto se realiza a través de la siguiente pregunta metodológica: ¿En qué medida la interpretación de Tomás de Aquino que Edith Stein ofrece en EES VII, 1-2, permite dilucidar la pregunta por la mujer?Taking into account the background outlined and constandy updated by Hanna-Barbara Gerl-Falkovitz, the present paper forms a brief response to the question raised about the relationship between Edith Stein and Thomas Aquinas in the light of a concise analysis of Endliches und Ewiges Sein VII, 1 -2, contextualized through the central axes of this great Steinian work. This analysis allows the appreciation of the dissimilar resemblance of understanding Edith Stein in relation to Thomas Aquinas, based on a key aspect of the Thomistic line of argument, that which is based on STh I q.29, Of the Divine People. This text is tackled through the following methodological question: To what extent does the interpretation of Thomas Aquinas offered by Edith Stein in EES VII, 1-2, help solve the «woman issue».

  15. Naranjas en el suelo. La conciencia de la muerte en la obra de Tomás González

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    Óscar Daniel Campo Becerra

    2012-07-01

    Full Text Available Este artículo propone una lectura crítica de la obra de Tomás González. En la primera parte, se muestra que la posición del narrador en la obra narrativa y la voz poética en su poesía están mediadas por una conciencia de la muerte que afecta la representación del mundo. Luego, se analizan los lazos familiares entre los personajes en las novelas, pues ellos permiten ver destinos trágicos, sensibilidades nerviosas y sentimientos culpables heredados que definen a los personajes masculinos. Además de las obras mismas de González, este trabajo se basa en entrevistas al autor, reseñas críticas sobre sus textos y afirmaciones explícitas o implícitas, derivadas de sus poemas y narraciones.

  16. Caracterización del perfil de los estudiantes de Negocios Internacionales de la Universidad Santo Tomás, sede Bogotá

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    Myriam Soraya Suárez R.

    2013-01-01

    Full Text Available Los estudios sobre el perfil de los estudiantes universitarios se han llevado a cabo permanentemente, debido a que las universidades requieren saber con qué estudiantes cuentan y cómo estos requieren ser formados, de acuerdo con las necesidades actua - les del mercado laboral y las necesidades sociales del contexto en el cual se encuentran inmersos. Esta investigación sobre la caracterización del perfil de los estudiantes de la Facultad de Negocios Internacionales de la Universidad Santo Tomás, sede Bogotá, determinó los aspectos biográficos, sociodemográficos, proyecto de vida, perfil educativo y profesional, competencias y uso del tiempo libre, con el fin de describir las motivaciones, intereses y percepciones, lo cual permitió tener un conocimiento holístico de los estudiantes y de todos los aspectos involucrados en su formación.

  17. FORMAS DE TRATAMENTO EM TRADUÇÕES DE “THE ADVENTURES OF TOM SAWYER”: RELAÇÕES SOCIAIS E AFETIVAS

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    Giselle Olivia Mantovani Dal Corno

    2015-02-01

    Full Text Available Mark Twain is a renowned realist author, known by his colloquial style and local colorism. In the novel “The adventures of Tom Sawyer”, he manages to depict oral regional language in the lines of his characters. Address forms used by characters contribute to the representation of social relations in the book. From the analysis of a few dialogs in the original text in English and their translations into Portuguese, this paper will discuss not only oral language indexes but also the ways how the choice of lexical items for addressing reveal different degrees of affectivity and social hierarchy. Some cases of loss in translation are registered as well as one case of domestication, in the terms of Venutti (1998.

  18. La voluntad humana en Tomás de Aquino. Un estudio desde sus fuentes griegas, patrísticas y escolásticas

    OpenAIRE

    García-Valiño Abós, Javier

    2010-01-01

    Este trabajo es una investigación sobre la voluntad humana en la filosofía griega, patrística y medieval, centrada principalmente en Tomás de Aquino como receptor de una rica reflexión multisecular, que elabora una síntesis original y sistemática sobre la voluntad. Todo ello, en diálogo con críticos y comentadores posteriores y un abanico amplio de autores del s. XX. El objeto de la tesis se sitúa en el ámbito de la antropología filosófica: es la voluntad como potencia o facultad del alma hum...

  19. Reading beyond the classroom. Effects and advantages of extensive reading practice focused to be part of the english programs at the Universidad Santo Tomás, Tunja

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    Nery Yolanda Ruiz de Guerrero

    2009-01-01

    Full Text Available El propósito de este trabajo es observar y describir los efectosde aplicar lectura extensiva a un grupo de estudiantes de quintonivel de Inglés de la Universidad Santo Tomás, dirigido a hacerparte del programa de Inglés. Este proyecto proporciona a losestudiantes un ambiente adecuado para el desarrollo de lecturaextensiva por medio de textos reales, que se caracteriza por lapráctica de lectura libre y controlada, en la cual los estudiantestienen la oportunidad de tomar sus propias decisiones bajo lasupervisión del profesor. La información fue recolectada a travésde los diarios de los profesores, de los reportes orales y escritosde los estudiantes y de las entrevistas realizadas a éstos.

  20. On Tom Regan's Postulate of Inherent Value%论汤姆·雷根的固有价值假定

    Institute of Scientific and Technical Information of China (English)

    李曦

    2010-01-01

    汤姆·雷根(Tom Regan)的(The Case for Animal Rights)是探讨动物权利问题的当代经典.汤姆·雷根为动物道德权利所作的辩护高度依赖于他的固有价值假定,即动物和人类一样具有平等的、不可通约的固有价值假定,这个假定尽管并不像一些批评者所认为的那样空洞无力,因此无法为动物的权利提供支持,但是汤姆·雷根应对其他批评的方式为这个假定带来了困难,导致他的立场根基不稳.

  1. Land flatworms (Platyhelminthes, Geoplanidae) of São Tomé: a first account on their diversity, with the description of five new species.

    Science.gov (United States)

    Sluys, Ronald; Neumann, Matthias; Lima, Ricardo F DE; Drewes, Robert C

    2017-01-17

    The present contribution provides the first faunistic and taxonomic account of six species of land flatworm from the island of São Tomé, including five new species of the genus Othelosoma Gray, 1869 and the introduced Bipalium kewense Moseley, 1878. One of the new species represents the first African land flatworm that has specks on its dorsal body surface, instead of stripes or a more or less uniform colouration. At least two of the new species were observed to prey on snails. The study details the fourth record of a sclerotic spermatophore in a species of land flatworm, and discusses the definition and homology of double female genital canals in African and Indian species of the genus Othelosoma.

  2. Una propuesta de lectura desde la écfrasis literaria en La Luz Difícil de Tomás González

    OpenAIRE

    Quintero Londoño, Claudia Patricia

    2014-01-01

    El objeto de este artículo es realizar una aproximación interpretativa de la novela La Luz Difícil de Tomás González, a partir de la noción de écfrasis desarrollada por el semiólogo francés, Michael de Riffaterre -- ¿De qué modo funciona esta figura en la configuración de la narración? Elucidar su caracterización y su intencionalidad en la obra es el propósito que anima este recorrido; en tanto que, la ejecución, la descripción y la interpretación de un cuadro son recreadas en paralelo al des...

  3. Prevalência de enteroparisitos na populaçao urbana de São Tomé - RN - estudo comparativo de um decênio

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    Carlos Alberto Moreira Campos

    1982-12-01

    Full Text Available Objetivando a obtenção de variáveis relacionadas aos fatores sócio-econômicos e sanitários no período de dez (10 anos, os autores colheram resultados sobre a prevalência de enteroparasitas na população urbana de São Tomé, Rio Grande do Norte, cujos dados foram coletados entre 09 a 27 de julho de 1979, empregando o método da sedimentação espontânea (Hoffmann, Pons e Janer, através de exames realizados em 826 amostras de fezes, com uma positividade de565 para as diversas parasitoses intestinais e correspondendo a uma prevalência de 68,4% em função das condições ambientais que, embora melhoradas, concorrem no processo de disseminação de helmintoses e protozooses, além de outras patologias.In view of socio-economic and sanitary changes during ten (10 years, the authors gathered data on the prevaíence of enteroparasites in the urban population of São Tomé, Rio Grande do Norte. They collected from July 9 to July 27, 1979, 826 faecal samples which they examined using the spontaneous sedimentation method (Hoffmann, Pons, and Janer. 565 were positive for the various intestinal parasites, corresponding to a prevaíence of 68,4%. Although environmetal conditions have improved, they still contributed to the dissemination intestinal protozoal and helminthic infections.

  4. Efeito da aplicação de nitrogênio e de piraclostrobina em plantas de tomateiro cultivar Micro-Tom

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    Emanuela Garbin Martinazzo

    Full Text Available RESUMO Fungicidas do grupo químico das estrobilurinas ganharam novas perspectivas de uso, em vista das vantagens obtidas pela ação dos efeitos fisiológicos positivos sobre as plantas. Este trabalho teve como objetivo verificar o efeito da piraclostrobina nos teores de pigmentos fotossintéticos e de nitrogênio na atividade da enzima redutase do nitrato, em plantas de tomateiro cv. Micro-Tom, cultivadas com diferentes doses de nitrogênio. Aos 21 dias após o transplante (DAT, as plantas foram submetidas aos tratamentos: solução nutritiva completa, sem piraclostrobina; solução nutritiva completa, com piraclostrobina; solução nutritiva com 1/2 força iônica de nitrogênio, sem piraclostrobina; e solução nutritiva com 1/2 força iônica de nitrogênio, com piraclostrobina. A aplicação da piraclostrobina foi repetida aos 35 DAT. Aos 28 e 42 DAT, determinaram-se o teor de pigmentos fotossintéticos, o nitrogênio total e a atividade da enzima redutase do nitrato. A aplicação de piraclostrobina promoveu aumento dos teores de pigmentos apenas aos 28 DAT, nas plantas com fornecimento reduzido de nitrogênio. Duas aplicações de piraclostrobina não influenciaram no conteúdo de nitrogênio e na atividade da redutase do nitrato de plantas de tomateiro cv. Micro-Tom, cultivadas em solução nutritiva de Hoagland e Arnon.

  5. Análise florística e estrutural de sistemas silviagrícolas em Tomé-Açu, Pará

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    Édson Luis Bolfe

    2011-10-01

    Full Text Available O objetivo deste trabalho foi analisar a composição florística e estrutural de sistemas silviagrícolas em Tomé-Açu, Pará. Os dados dendrométricos foram obtidos por inventário em 40 parcelas amostrais, com três unidades cada uma, no total de 120 unidades de 10x10 m. Foi inventariada a média de 1.424,3 indivíduos por hectare, pertencentes a 27 famílias e a 54 espécies. Tendo-se considerado a variabilidade dos estágios vegetativos, os diferentes sistemas silviagrícolas (SAF foram divididos em quatro classes hierárquicas: SAF 1, SAF 2, SAF 3, e SAF 4, para estabelecer um sistema de classificação passível de ser utilizado em outras avaliações de campo e em classificações digitais por meio do sensoriamento remoto. Espécies observadas em outros sistemas da região amazônica também foram relevantes para este estudo, especialmente Theobroma cacao, T. grandiflorum e Euterpe oleracea que, juntas, apresentaram médias de frequência relativa de 51%, densidade relativa de 69,2%, dominância relativa de 50,1% e índice de valor de importância de 56,8%. Os dados médios de diversidade florística, abundância, área basal e valor de importância indicam os sistemas silviagrícolas da região de Tomé-Açu como sistemas de produção com potencial econômico e ambiental, se adotado manejo adequado e racional.

  6. Book Review: The Art of Innovation Lessons in Creativity from IDEO America’s leading design firm by Kelley, Tom, (with Jonathan Littman), Doubleday, New York, 2001, ISBN 0-385-499-84-1

    NARCIS (Netherlands)

    Meer, van der Han

    2005-01-01

    Find in Kelley’s book a vibrant and modern example of the organic firm and the principles of such firms in American society. Kelly (1955) is general manager of IDEO a famous American design firm founded by his brother Tom in the early 1970s. The book is all about this firm where innovation is the li

  7. The Role of Physical Context, Verbal Skills, Non-Parental Care, Social Support, and Type of Parental Discipline in the Development of ToM Capacity in Five-Year-Old Children

    Science.gov (United States)

    Galende, Nuria; de Miguel, Manuel Sanchez; Arranz, Enrique

    2011-01-01

    The aim of this study was to analyze the influence of family context on the performance of 5-year-old children (N = 70) in theory of mind (ToM) tasks. The children's performances were assessed during individual sessions held at school. Children's verbal skills were assessed using the Peabody picture vocabulary test (PPVT). Interviews were also…

  8. The collection of birds from São Tomé and Príncipe at the Instituto de Investigação Científica Tropical of the University of Lisbon (Portugal)

    Science.gov (United States)

    Monteiro, Miguel; Reino, Luís; Melo, Martim; Beja, Pedro; Bastos-Silveira, Cristiane; Ramos, Manuela; Rodrigues, Diana; Neves, Isabel Queirós; Consciência, Susana; Figueira, Rui

    2016-01-01

    Abstract The former Instituto de Investigação Científica Tropical-IICT (Lisbon, Portugal), recently integrated into the University of Lisbon, gathers important natural history collections from Portuguese-speaking African countries. In this study, we describe the bird collection from the Democratic Republic of São Tomé and Príncipe, which was fully taxonomically checked and georeferenced. The IICT bird collection contains 5598 specimens, of which 559 are from São Tomé and Príncipe, representing 85 taxa, including 19 endemic species and 13 endemic subspecies of birds. The specimens were collected between 1946 and 1973, although 43% of the records are from 1954 and 45% are from 1970. The geographic distribution of samples covers the whole territory, with a higher number of records from São Tomé than from Príncipe. The districts with highest number of records are Pagué (equivalent to Príncipe Island), and Água Grande and Mé-Zochi on São Tomé. Despite the relatively low number of specimens per taxon, the importance of the collection is considerable due to the high number of endemic and threatened species represented. Furthermore, it adds valuable information to the GBIF network, especially for a country whose two islands are each an Endemic Bird Area and for which substantial gaps in ornithological knowledge remain. PMID:27408605

  9. The collection of birds from São Tomé and Príncipe at the Instituto de Investigação Científica Tropical of the University of Lisbon (Portugal).

    Science.gov (United States)

    Monteiro, Miguel; Reino, Luís; Melo, Martim; Beja, Pedro; Bastos-Silveira, Cristiane; Ramos, Manuela; Rodrigues, Diana; Neves, Isabel Queirós; Consciência, Susana; Figueira, Rui

    2016-01-01

    The former Instituto de Investigação Científica Tropical-IICT (Lisbon, Portugal), recently integrated into the University of Lisbon, gathers important natural history collections from Portuguese-speaking African countries. In this study, we describe the bird collection from the Democratic Republic of São Tomé and Príncipe, which was fully taxonomically checked and georeferenced. The IICT bird collection contains 5598 specimens, of which 559 are from São Tomé and Príncipe, representing 85 taxa, including 19 endemic species and 13 endemic subspecies of birds. The specimens were collected between 1946 and 1973, although 43% of the records are from 1954 and 45% are from 1970. The geographic distribution of samples covers the whole territory, with a higher number of records from São Tomé than from Príncipe. The districts with highest number of records are Pagué (equivalent to Príncipe Island), and Água Grande and Mé-Zochi on São Tomé. Despite the relatively low number of specimens per taxon, the importance of the collection is considerable due to the high number of endemic and threatened species represented. Furthermore, it adds valuable information to the GBIF network, especially for a country whose two islands are each an Endemic Bird Area and for which substantial gaps in ornithological knowledge remain.

  10. Wave activity (planetary, tidal throughout the middle atmosphere (20-100km over the CUJO network: Satellite (TOMS and Medium Frequency (MF radar observations

    Directory of Open Access Journals (Sweden)

    A. H. Manson

    2005-02-01

    Full Text Available Planetary and tidal wave activity in the tropopause-lower stratosphere and mesosphere-lower thermosphere (MLT is studied using combinations of ground-based (GB and satellite instruments (2000-2002. The relatively new MFR (medium frequency radar at Platteville (40° N, 105° W has provided the opportunity to create an operational network of middle-latitude MFRs, stretching from 81° W-142° E, which provides winds and tides 70-100km. CUJO (Canada U.S. Japan Opportunity comprises systems at London (43° N, 81° W, Platteville (40° N, 105° W, Saskatoon (52° N, 107° W, Wakkanai (45° N, 142° E and Yamagawa (31° N, 131° E. It offers a significant 7000-km longitudinal sector in the North American-Pacific region, and a useful range of latitudes (12-14° at two longitudes. Satellite data mainly involve the daily values of the total ozone column measured by the Earth Probe (EP TOMS (Total Ozone Mapping Spectrometer and provide a measure of tropopause-lower stratospheric planetary wave activity, as well as ozone variability.

    Climatologies of ozone and winds/tides involving frequency versus time (wavelet contour plots for periods from 2-d to 30-d and the interval from mid 2000 to 2002, show that the changes with altitude, longitude and latitude are very significant and distinctive. Geometric-mean wavelets for the region of the 40° N MFRs demonstrate occasions during the autumn, winter and spring months when there are similarities in the spectral features of the lower atmosphere and at mesopause (85km heights. Both direct planetary wave (PW propagation into the MLT, nonlinear PW-tide interactions, and disturbances in MLT tides associated with fluctuations in the ozone forcing are considered to be possible coupling processes. The complex horizontal wave numbers of the longer period oscillations are provided in frequency contour plots for the TOMS satellite data to demonstrate the differences between lower atmospheric

  11. Wave activity (planetary, tidal) throughout the middle atmosphere (20-100km) over the CUJO network: Satellite (TOMS) and Medium Frequency (MF) radar observations

    Science.gov (United States)

    Manson, A. H.; Meek, C. E.; Chshyolkova, T.; Avery, S. K.; Thorsen, D.; MacDougall, J. W.; Hocking, W.; Murayama, Y.; Igarashi, K.

    2005-02-01

    Planetary and tidal wave activity in the tropopause-lower stratosphere and mesosphere-lower thermosphere (MLT) is studied using combinations of ground-based (GB) and satellite instruments (2000-2002). The relatively new MFR (medium frequency radar) at Platteville (40° N, 105° W) has provided the opportunity to create an operational network of middle-latitude MFRs, stretching from 81° W-142° E, which provides winds and tides 70-100km. CUJO (Canada U.S. Japan Opportunity) comprises systems at London (43° N, 81° W), Platteville (40° N, 105° W), Saskatoon (52° N, 107° W), Wakkanai (45° N, 142° E) and Yamagawa (31° N, 131° E). It offers a significant 7000-km longitudinal sector in the North American-Pacific region, and a useful range of latitudes (12-14°) at two longitudes. Satellite data mainly involve the daily values of the total ozone column measured by the Earth Probe (EP) TOMS (Total Ozone Mapping Spectrometer) and provide a measure of tropopause-lower stratospheric planetary wave activity, as well as ozone variability. Climatologies of ozone and winds/tides involving frequency versus time (wavelet) contour plots for periods from 2-d to 30-d and the interval from mid 2000 to 2002, show that the changes with altitude, longitude and latitude are very significant and distinctive. Geometric-mean wavelets for the region of the 40° N MFRs demonstrate occasions during the autumn, winter and spring months when there are similarities in the spectral features of the lower atmosphere and at mesopause (85km) heights. Both direct planetary wave (PW) propagation into the MLT, nonlinear PW-tide interactions, and disturbances in MLT tides associated with fluctuations in the ozone forcing are considered to be possible coupling processes. The complex horizontal wave numbers of the longer period oscillations are provided in frequency contour plots for the TOMS satellite data to demonstrate the differences between lower atmospheric and MLT wave motions and their

  12. A Study of Features of Fielding's Novel Tom Jones%《汤姆· 琼斯》创作特点研究

    Institute of Scientific and Technical Information of China (English)

    郑佩伟; 张景玲

    2016-01-01

    Henry Fielding is the most important realistic novelist both in England and even in Europe in the 18th century.In the developing course of English novels and the establishing of all the forms of modern no -vels, his importance as a novelist is incomparable , so he is regarded as "the Father of English Fiction". While he values the ideological content of the novel , Fielding pays more attention to formal elements of the no-vel.His masterpiece Tom Jones has its salient artistic features in terms of structure , dramatic elements, edu-cational function and language style .%亨利· 菲尔丁是18世纪英国乃至欧洲最重要的现实主义小说家,在英国小说的发展过程和确立现代小说的形式方面,他的重要性是无与伦比的,有着"英国小说之父"的称号. 菲尔丁在注重小说思想性的同时,也格外关注小说形式方面的问题,其代表作《汤姆· 琼斯》在框架结构、戏剧成分、教育功能和语言风格等方面都有其鲜明的创作特点.

  13. Bivariate genome-wide association meta-analysis of pediatric musculoskeletal traits reveals pleiotropic effects at the SREBF1/TOM1L2 locus.

    Science.gov (United States)

    Medina-Gomez, Carolina; Kemp, John P; Dimou, Niki L; Kreiner, Eskil; Chesi, Alessandra; Zemel, Babette S; Bønnelykke, Klaus; Boer, Cindy G; Ahluwalia, Tarunveer S; Bisgaard, Hans; Evangelou, Evangelos; Heppe, Denise H M; Bonewald, Lynda F; Gorski, Jeffrey P; Ghanbari, Mohsen; Demissie, Serkalem; Duque, Gustavo; Maurano, Matthew T; Kiel, Douglas P; Hsu, Yi-Hsiang; C J van der Eerden, Bram; Ackert-Bicknell, Cheryl; Reppe, Sjur; Gautvik, Kaare M; Raastad, Truls; Karasik, David; van de Peppel, Jeroen; Jaddoe, Vincent W V; Uitterlinden, André G; Tobias, Jonathan H; Grant, Struan F A; Bagos, Pantelis G; Evans, David M; Rivadeneira, Fernando

    2017-07-25

    Bone mineral density is known to be a heritable, polygenic trait whereas genetic variants contributing to lean mass variation remain largely unknown. We estimated the shared SNP heritability and performed a bivariate GWAS meta-analysis of total-body lean mass (TB-LM) and total-body less head bone mineral density (TBLH-BMD) regions in 10,414 children. The estimated SNP heritability is 43% (95% CI: 34-52%) for TBLH-BMD, and 39% (95% CI: 30-48%) for TB-LM, with a shared genetic component of 43% (95% CI: 29-56%). We identify variants with pleiotropic effects in eight loci, including seven established bone mineral density loci: WNT4, GALNT3, MEPE, CPED1/WNT16, TNFSF11, RIN3, and PPP6R3/LRP5. Variants in the TOM1L2/SREBF1 locus exert opposing effects TB-LM and TBLH-BMD, and have a stronger association with the former trait. We show that SREBF1 is expressed in murine and human osteoblasts, as well as in human muscle tissue. This is the first bivariate GWAS meta-analysis to demonstrate genetic factors with pleiotropic effects on bone mineral density and lean mass.Bone mineral density and lean skeletal mass are heritable traits. Here, Medina-Gomez and colleagues perform bivariate GWAS analyses of total body lean mass and bone mass density in children, and show genetic loci with pleiotropic effects on both traits.

  14. 林译《黑奴吁天录》的修辞解读%A Rhetorical Interpretation of Lin Shu's T ranslation of Uncle Tom's Cabin

    Institute of Scientific and Technical Information of China (English)

    李艳玲

    2015-01-01

    T his paper applies the theory of rhetoric to an analysis of the Chinese translation of Uncle Tom's Cabin by Lin Shu .It interprets the manipulation of the material in the source text and the focus of the study is how the translator centered on target audience ,applying different rhetorical means to the translation to achieve his intention of the translation .%文章以西方修辞理论为参照,以个案研究的方法重新解读林译《黑奴吁天录》,重点分析译者在文本选择、话语建构及内容删改等方面,如何以受众为中心,诉诸各种修辞手段来处理原文本的内容,以圆满地实现自己的修辞意图。

  15. Dos Paradigmas Hermenéuticos del Pensamiento Político de Tomás de Aquino: sus Virtudes, Limitaciones y Virtualidades

    Directory of Open Access Journals (Sweden)

    Santiago Argüello

    2016-06-01

    Full Text Available RESUMEN: El presente trabajo examina dos de los principales modelos de exposición del pensamiento político de Tomás de Aquino vigentes en el siglo XX. Uno, en cuya representación se ha escogido la obra de Eschmann, mira a la relación de la obra del Aquinate con sus predecesores; el otro, adecuadamente representado por Ullmann, mira a la relación de dicha obra con el pensamiento que se proyecta a partir de él hacia la Modernidad. Al determinar tanto las virtudes cuanto limitaciones propias de estos modelos hermenéuticos, se hace posible advertir las virtualidades presentes en los mismos, abriendo nuevos caminos de investigación que superen la tensión concebida entre el poder eclesiástico y el civil, así como el temor por reanimar un concepto que, si bien embrionario en la obra del autor medieval, es imprescindible para comprender cabalmente su reactivación del republicanismo aristotélico. Tal es el concepto de nación.

  16. Inmanencia, intencionalidad y representación en Tomás de Aquino Immanence, Intentionality and Representation in Thomas Aquinas

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    Patricia Moya Cañas

    2013-03-01

    Full Text Available El artículo se propone rehabilitar el concepto tomasiano de representación cognoscitiva que es fuertemente criticado en su versión post cartesiana. Con este objetivo se contextualiza la representación en el marco más amplio de otras características que Tomás de Aquino atribuye al conocimiento humano, concretamente las de inmanencia e intencionalidad. El análisis de estos atributos del conocimiento permite establecer el ámbito propio del acto cognoscitivo, diferenciándolo de una condición física o naturalThis article aims at recovering Aquinas’ concept of cognitive representation which is strongly criticized in its post-cartesian sense. For this purpose, representation is contextualized in the wider frame of other characteristics that Thomas Aquinas attributes to human knowledge, i.e. that of immanence and intentionality. The analysis of these features allows to establish the proper scope of the cognitive act and to differentiate it from a physical or natural condition.

  17. 'Semicreolization'? – The restructured Portuguese of the Tongas of São Tomé, a consequence of L1 acquisition in a special contact situation

    Directory of Open Access Journals (Sweden)

    Alan Baxter

    2002-06-01

    Full Text Available This paper discusses aspects of language transmission among the Tongas of São Tomé, the descendants of indentured Africans, on the Monte Café plantation where restructured Portuguese developed alongside an Umbundu-based koiné. It considers the sociohistorical context of language acquisition and transmission, and the role of Portuguese L2 influence in primary linguistic data (PLD for L1 acquisition in this speech community. In the Tonga Portuguese of a first generation born to African parents, these processes gave rise to broad restructuring relative to (i agreement rules (number, gender, and subject-verb, (ii verb and tense and aspect marking, (iii the signalling of definite and indefinite reference, and (iv negation. These restructurings constitute a variable set resembling, in form and function, structures found in varieties of Creole Portuguese. However, the consequences in Tonga Portuguese are only slight in comparison, so the language appears to have been partially creolized. The motivation for restructuring is viewed both from DeGraff’s perspective of a Universal Grammar approach to acquisition and creolization, stressing the quality of PLD and its role in yielding unmarked structures, and from the perspective of Bantu substrate influence. Finally, discussion turns to Holm’s notion of ‘semi-creole’ and the validity of classifying Tonga Portuguese in these terms.

  18. Phylogeography of Mabuya maculilabris (Reptilia) from São Tomé Island (Gulf of Guinea) inferred from mtDNA sequences.

    Science.gov (United States)

    Jesus, José; Harris, D James; Brehm, António

    2005-11-01

    The pattern of genetic variation of the lizard Mabuya maculilabris from São Tomé Island (Gulf of Guinea) was investigated using a combination of three mitochondrial DNA gene fragments. Forty-eight haplotypes were recovered among 66 individuals covering the whole island. The genealogy inferred from the most parsimonious network of haplotypes allows us to detect two main and long branches departing from the putative group of oldest haplotypes. The tips of these branches exhibit star-like phylogenies, which may indicate of recently expanded populations, most probably from a small number of founders. A nested clade analysis suggests a complex pattern of past events that gave rise to the extant geographical pattern found in the haplotype distribution: past and allopatric fragmentation, range expansion, restricted gene flow and long-distance dispersal. These results are consistent with the complex geological history of the island where important volcanic activity with extensive lava flows has occurred during several periods. Mismatch-distribution analysis and AMOVA also support these conclusions. Substantial genetic structuring among these lizards was detected as well as high levels of differentiation between the southern edge populations (particularly those from the Rolas Islet) and the remaining ones. However, variation is low relative to the geological age of the island. Our results indicate that patterns of variation observed in reptiles in other oceanic islands are not indicative of those observed in the islands of the Gulf of Guinea.

  19. DE-MYTHOLOGIZING THE BARD: APPROPRIATION OF SHAKESPEARE IN TOM STOPPARD’S DOGG’S HAMLET, CAHOOT’S MACBETH

    Directory of Open Access Journals (Sweden)

    Ifeta Ciric-Fazlija

    2014-11-01

    Full Text Available One of the most entrenched myths that dramatic authors need to contest and adjust to is the Shakespeare myth, a long-lasting and all-pervasive influence that Shakespeare’s name and texts have exerted since the late 16th century, being perceived as “represent[ing] truths that transcend particular circumstances” (Sinfield, 1998: 129. In order to be actively involved in the “making of culture” (Sinfield, 1998: 128 and for the purpose of establishing and (redefining one’s own position within and against the canonical (transnational texts, many British dramatists, including Tom Stoppard, have alluded to, quoted, or incorporated portions of Shakespeare’s plays within their own, or even reconstituted them completely. This paper discusses the manner in which Stoppard appropriates Shakespeare’s Hamlet and Macbeth – probably his best known and most frequently staged and adapted tragedies – in order to question the importance of both the author and his work within the context of contemporary culture and society.

  20. 家具设计师Tom Dixon联手日本建筑师设计新型建筑材料

    Institute of Scientific and Technical Information of China (English)

    赖芳

    2007-01-01

    <正>家居设计界最有影响力的设计师、芬兰设计公司Artek的创意总监Tom Dixon今年除了推出自己品牌的新作品之外,还与日本建筑设计师Shigeru Ban联手合作,建造一个用来展示Artek的新Bambu系列的大棚子。目前座落于米兰Triennale公园的这个展示棚,最特别之处在于它使用了芬兰林业公司UPM从自粘胶带中研制出的一种新型材料。这种新型材料含40%的可循环塑料和60%的木材,作为建筑材料来说有非常多的优点,它比塑料更轻,在户外

  1. Estrategias para mejorar el impacto de las publicaciones indexadas en Publindex, ISI, Scopus y SciELO: el caso de la Universidad Santo Tomás, Colombia

    Directory of Open Access Journals (Sweden)

    Julián Andrés Pacheco

    2013-01-01

    Full Text Available El presente artículo de investigación, que parte de un análisis bibliométrico, tuvo como propósito determinar el número de publicaciones de los docentes de la Universidad Santo Tomás (USTA, Colombia, en bases de indexación como ISI, Scopus, SciELO y Publindex. Mediante diferentes datos estadísticos, obtenidos de los reportes de los principales sistemas de indexación, se analizó el impacto de las publicaciones de la USTA a nivel nacional e internacional y se delimitaron algunas estrategias para mejorar la participación actual de los docentes de la universidad en sistemas de indexación extranjeros. Desde este panorama, el presente documento expone la importancia de catalogar las publicaciones de las instituciones de educación superior en sistemas de indexación y resumen internacionales, junto con las distintas formas de asegurar el factor de impacto de un autor determinado, entre otros criterios para la inclusión de la producción científica en la sociedad del conocimiento.

  2. Design of an enhanced Integrated Management System with Customer Experience Focus: The Business Process Framework (also known as eTOM and ISO9001 Together

    Directory of Open Access Journals (Sweden)

    John P. Reilly

    2012-09-01

    Full Text Available The purpose of this paper is to suggest an enhanced Process model with customer experience focus and its related documentation structure applicable to many industrial contexts. Since the Business Process Framework, also known as eTOM, is originally a Process Model for Telco industry and now being used broadly in many industries, ISO9001 is a historical and generic standard with customer focus, and there is always a question about how to integrate the Business Process Framework and ISO9001, the enhanced process model will be based on the integration of the Business Process Framework and ISO9001 highlighting the customer aspects to meet the current trends within Telco and many other industries. The management system, containing the organization, the processes based on this integration, and the performance management system is called an Integrated Management System (IMS. The paper focus is on the processes and its introduction is about Telco Business context since the Business Process Framework was born within this industry. But, the suggested IMS is applicable to many service companies and many organizational units of any industry (Ex.: any Information System organizational unit, with its service Portfolios, of any industry since the Business Process Framework and ISO9001 are too.

  3. Valor inerente e vulnerabilidade: critérios éticos não-especistas na perspectiva de Tom Regan

    Directory of Open Access Journals (Sweden)

    Sônia T. Felipe

    2009-07-01

    Full Text Available http://dx.doi.org/10.5007/1677-2954.2009v8n1p147Seres vivos de todas as espécies têm sido considerados objetos de propriedade, passíveis de serem explorados para atender aos desejos, fantasias e necessidades humanas. Filósofos morais utilitaristas, a exemplo de Peter Singer, propõem princípios éticos para definir os limites da liberdade humana em relação a todos os seres sencientes. Mas, o critério da senciência, no caso da formulação de uma ética ambiental genuína, não pode ser aplicado à natureza ambiental, nem mesmo a todos os seres vivos, exceto aos mamíferos e aves. Neste artigo, reconstituo os argumentos de Tom Regan para fundamentar a ética animal e os critérios necessários, na perspectiva desse filósofo moral, para a fundamentação de uma ética ambiental.

  4. La ratio legis en la teología de Suarez y Santo Tomás: Una propuesta de comparación

    Directory of Open Access Journals (Sweden)

    Sebastián Contreras

    2012-01-01

    Full Text Available El presente trabajo intenta profundizar en las nociones de ley de dos de los más importantes teólogos escolásticos:Tomás de Aquino y Francisco Suárez. Sabemos que el Eximio pretende dar sentido e inteligencia a las palabras del Aquinatense. Usualmente se ha marcado el voluntarismo y distancia que toma Suárez con respecto a la teologia del Maestro Angélico, motivo por el cual hemos querido bosquejar una posible continuidad entre ambos doctores de la teologia escolástica: todo a partir del análisis del concepto de imperium.This paper tries deeper into the notions of law of two of the most important scholastics: Aquinas and Suarez. We know that Suarez tries give sense and intelligence at the Aquinas' words. Usually we mark the voluntarism and the distance that Suarez takes over the Aquinas' theology; for this we wanted outline a possible continuity between the two doctors of scholastic theology: everything from the analysis of the concept of imperium.

  5. Measurements of the total ozone column using a Brewer spectrophotometer and TOMS and OMI satellite instruments over the Southern Space Observatory in Brazil

    Science.gov (United States)

    Vaz Peres, Lucas; Bencherif, Hassan; Mbatha, Nkanyiso; Passaglia Schuch, André; Toihir, Abdoulwahab Mohamed; Bègue, Nelson; Portafaix, Thierry; Anabor, Vagner; Kirsch Pinheiro, Damaris; Paes Leme, Neusa Maria; Valentin Bageston, José; Schuch, Nelson Jorge

    2017-01-01

    This paper presents 23 years (1992-2014) of quasi-continuous measurements of the total ozone column (TOC) over the Southern Space Observatory (SSO) in São Martinho da Serra, Brazil (29.26° S, 53.48° and 488 m altitude). The TOC was measured by a Brewer spectrometer, and the results are also compared to daily and monthly observations from the TOMS (Total Ozone Mapping Spectrometer) and OMI (Ozone Monitoring Instrument) satellite instruments. Analyses of the main interannual modes of variability computed using the wavelet transform method were performed. A favorable agreement between the Brewer spectrophotometer and satellite datasets was found. The seasonal TOC variation is dominated by an annual cycle, with a minimum of approximately 260 DU in April and a maximum of approximately 295 DU in September. The wavelet analysis applied in the SSO TOC anomaly time series revealed that the Quasi-Biennial Oscillation (QBO) modulation was the main mode of interannual variability. The comparison between the SSO TOC anomaly time series with the QBO index revealed that the two are in opposite phases.

  6. Formas de evaluación educativa en la Universidad Santo Tomás sede Bogotá, modalidad presencial. Elementos para una caracterización

    Directory of Open Access Journals (Sweden)

    Grupo de Investigación Docimófilos

    2009-01-01

    Full Text Available La indagación realizada por el Grupo de Investigación Docimó-ęlos, apuntó hacia una caracterización de las Formas de Evalua-ción Educativa presentes en la Universidad Santo Tomás SedeBogotá, Modalidad Presencial. En tal perspectiva, se usó una delas herramientas teórico-metodológicas del arsenal foucaultiano:la arqueología. El estudio se fundamentó en el análisis de diver-sos discursos -y prácticas- que se han desarrollado en torno delobjeto evaluación que se han instalado en la institución, sobre labase de una amplia masa documental. La analítica de la verdadhizo posible la identięcación de una pluralidad de modalidadesevaluativas que permiten: la producción de saber, la objetivaciónde las relaciones de poder y la conęguración de subjetividades.

  7. Procesos de (desmitificación en la novella de perón y Santa Evita de Tomás Eloy Martínez

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    Diógenes Fajardo Valenzuela

    1996-12-01

    Full Text Available Al estudiar la Hamada Generación parricida de 1955, en la Argentina, notaba cómo «no obstante el peso del peronismo sobre los escritores argentinas, todavía no se había escrito una gran novela sobre el tema». Hoy encuentro respuesta eficaz a esta carencia en las dos novelas de Tomás Eloy Martínez que vienen a incrementar la ya larga lista de textos que directa o indirectamente se refieren al Peronismo. Precisamente este narrador se encarga de ilustrar a su lector, en Santa Evita, sobre algunos textos, básicamente cuentos o ensayos en los cuales los autores del Rió de la Plata han reelaborado el tema casi vedado del peronismo. Para el periodista/novelista argentino «algunos de los mejores relatos de los años cincuenta son una parodia» de la muerte de "ella", de "esa mujer", puesto que «los escritores necesitaban olvidar a Evita, conjurar su fantasma.» (SE: 198

  8. Prevalência de enteroparisitos na populaçao urbana de São Tomé - RN - estudo comparativo de um decênio

    Directory of Open Access Journals (Sweden)

    Carlos Alberto Moreira Campos

    1982-12-01

    Full Text Available Objetivando a obtenção de variáveis relacionadas aos fatores sócio-econômicos e sanitários no período de dez (10 anos, os autores colheram resultados sobre a prevalência de enteroparasitas na população urbana de São Tomé, Rio Grande do Norte, cujos dados foram coletados entre 09 a 27 de julho de 1979, empregando o método da sedimentação espontânea (Hoffmann, Pons e Janer, através de exames realizados em 826 amostras de fezes, com uma positividade de565 para as diversas parasitoses intestinais e correspondendo a uma prevalência de 68,4% em função das condições ambientais que, embora melhoradas, concorrem no processo de disseminação de helmintoses e protozooses, além de outras patologias.

  9. Inseguridad ciudadana y diferenciación social en el nivel microbarrial: el caso del sector Santo Tomás, Santiago de Chile

    Directory of Open Access Journals (Sweden)

    Alejandra Lunecke

    2016-01-01

    Full Text Available En la periferia de la ciudad de Santiago se observan zonas de viviendas sociales que se caracterizan por una alta concentración de precariedades económicas y materiales, segregación espacial, procesos de debilitamiento del tejido comunitario y altos niveles de inseguridad, esto último por la presencia de grupos vinculados a la criminalidad. En tal contexto, a partir de una investigación realizada en el sector Santo Tomás de la zona sur de Santiago de Chile, se analiza cómo incide en los procesos de debilitamiento del tejido social, la percepción de inseguridad asociada al delito y la violencia, en un medio de pobreza guetizada. Para ello se pone énfasis en las prácticas discursivas de los vecinos, las que dan cuenta de los juicios de valor existentes respecto de "lo peligroso" y "lo desviado". Se discute cómo dichos juicios refuerzan las dinámicas de distinción social existentes en el nivel micro barrial y se alimentan de ellas.

  10. Proyección científica de las ideas de Tomás Romay sobre la vacuna de la viruela en la inclusa madrileña

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    Ramírez Martín, Susana María

    2002-12-01

    Full Text Available This paper is about scientific and medical activities of Dr Tomás Romay Chacón. He was a pioneer of the fight agianst smallpox in America. We present here a breef biography of Dr. Romay and a document about vaccination against smallpox in La Habana.

    En el artículo se pone de manifiesto la trayectoria científica y médica del Dr. Tomás Romay y Chacón. Este médico habanero es un ejemplo de lucha contra las viruelas en América. Su actividad científica no se limitó a la isla de Cuba, sino que su saber llegó hasta la Inclusa Madrileña. A esta institución benéfica llegaron sus escritos en el año 1813.

  11. Tomás de Aquino, Anselmo de Canterbury e a crítica da razão teológica = Aquinas and Anselm: a critique of theological reason

    Directory of Open Access Journals (Sweden)

    Jean Lauand

    2010-01-01

    Full Text Available Em 2009 se comemorou o 9º. centenário da morte de S. Anselmo (1033-1109. O artigo examina sua proposta de Teologia como ciência em contraste com a de Tomás de Aquino (1125-1274: as “rationes necessariae” anselmianas - no caso da Teologia da Redenção no "Cur Deus Homo?" - são confrontadas com as do Aquinate, contextualizadas pelo quadro geral do pensamento de Tomás.Nine hundred years after the death of Anselm of Canterbury, this article examines his idea of Theology as a science in contrast with Aquinas’s analysis of the same subject: the “rationes necessariae” ofAnselm – in Theology of Redemption in his work “Cur Deus Homo?” – are compared with the reasons of Thomas Aquinas, who emphasizes the liberty of God.

  12. O papel do sistema pecuário familiar na qualidade de vida dos agricultores-criadores das comunidades Monte Macaco e Santa Margarida - Ilha de São Tomé The paper of familiar pecuniary system in the life quality of: livestock smallholders of Monte Macaco and Santa Margarida comunities - São Tomé Island

    Directory of Open Access Journals (Sweden)

    Luís Filipe Bandeira Bonfim

    2008-12-01

    Full Text Available O estudo visa levantar problemas prioritários e propor estratégias e acções que o sistema pecuário familiar pode desempenhar para redução da pobreza e melhoria da qualidade de vida das Comunidades Monte Macaco e Santa Margarida na Ilha de São Tomé. Não é conclusivo, mas aponta como principal causa das dificuldades a falta de dinheiro para fazer face a problemas sanitários, de alojamento e de alimentação para animais, situação agravada pelo roubo destes e mau funcionamento das Associações. A discussão sobre as causas levou à proposta de soluções tendentes a ultrapassar as dificuldades. Os agricultores-criadores propõem a elaboração de um projecto de intervenção para melhorar o sistema e a qualidade de vida. Nesse sentido, o estudo sugere realização de uma oficina comunitária, planeamento participativo e um inquérito formal concomitante.The study aimed to identify main problems and find out strategies and actions to be taken by livestock smallholders to reduce poverty and improve quality of life of Monte Macaco and Santa Margarida Comunities of São Tomé Island. Although it is inconclusive, the result shows that lack of fïnancing support to invest on animal health, housing and feeding is the main constraint for livestock smalholders production and it becomes worst due to animal robbery and weakness of Comunnity Associations. Discussion about causes led to the proposal of actions to overcome difficulties. Livestock smallholders suggested an intervention project to enhance the system and the quality of life. In this sense, there should be workshops, leading to the participative planning of Community and based on formal surveys.

  13. Tom's “Blind” Figurative Meaning Interpretation in “The Golden Notebook”%《金色笔记》中汤姆“眼瞎”的喻义解读

    Institute of Scientific and Technical Information of China (English)

    宋晓霞

    2012-01-01

    "眼瞎"在文学作品中是一个常见的比喻,历来为评论家们所重视。然而,《金色笔记》中汤姆眼瞎的情节长期以来却为人们所忽视。与以往文学作品中的眼瞎一样,汤姆的眼瞎在这部小说中有着深刻的喻义。它不仅意味着汤姆对现实世界的逃避,更意味着汤姆精神世界的完整与对完整自我的把握。同时,它的存在彰显了主人公安娜摆脱分裂获得完整自我的积极意义,是与主题相呼应的重要情节。%"Blind" is a common metaphor in literature,has historically been a critics' attention.However,the plot of "The Golden Notebook" Tom's blind standing for people overlooked.Previous literary works in blind Tom blindness in the novel has a profound figurative meaning.Not only does it mean that Tom on the real world to escape,but also means that Tom spirit world complete with full self grasp.The same time,its presence highlights the protagonist Anna to get rid of split the positive significance of the complete self is an important theme echoes the plot.

  14. Sindérese, o intellectus principiorum da razão prática segundo Tomás de Aquino = Synderesis, the intellectus principiorum of practical reason according to Thomas Aquinas

    Directory of Open Access Journals (Sweden)

    Abertuni, Carlos Alberto

    2011-01-01

    Full Text Available Trata-se de uma investigação sobre a teoria dos primeiros princípios da razão prática na obra de Tomás de Aquino. No centro dessa teoria está o termo “sindérese”, cujo conteúdo foi elaborado nas discussões da filosofia e da teologia medievais, a partir de sua menção na Glosa de Jerônimo a Ezequiel. Tal termo designa um conceito que apresenta um caráter inovador dentro da teoria da ação moral em comparação com a ética aristotélica. Afinal, Tomás de Aquino o entende como o hábito dos primeiros princípios da moral, equivalente ao hábito dos primeiros princípios teóricos de Aristóteles. Dessa forma, o interesse é compreender como o conceito de sindérese é recebido e desenvolvido na filosofia moral de Tomás de Aquino através da análise das três questões tradicionais: de sua natureza, de sua infalibilidade e de sua extinção

  15. Frequency of the CCR5-delta32 mutation in the Atlantic island populations of Madeira, the Azores, Cabo Verde, and São Tomé e Príncipe.

    Science.gov (United States)

    Freitas, Tamira; Brehm, António; Fernandes, Ana Teresa

    2006-12-01

    There is evidence that the CCR5-delta32 mutation confers protection against HIV-1 infection to homozygous individuals. It is believed that this mutation spread through Europe with the Vikings and that it has been subjected to positive selection, leading to a high frequency in Europe (approximately 10%). We carried out the present study to determine the 32-bp deletion allele and genotype frequencies of the CCR5 gene (CCR5-delta32) in the Atlantic island populations of Madeira, the Azores, Cabo Verde, and São Tomé e Principe. These Atlantic archipelagos were all colonized by the Portuguese in the 15th and 16th centuries, but the latter two received most of their settlers from the West African coast. The frequency of the CCR5-delta32 mutation varies between 0% in São Tomé e Príncipe and 16.5% in the Azores. The Azores Islands have one of the highest frequencies of homozygotes found in Europe (4.8%). There are significant differences (P < 0.05) between some of these populations, for example, between São Tomé e Príncipe and Cabo Verde, and even within populations (e.g., Portugal, Madeira, and the Azores).

  16. Dolines in Sierra de Quemado and their relationship with the development of the Gran Caverna de Santo Tomàs, Vinales, Cuba

    Science.gov (United States)

    Farfan Gonzalez, Hermes; Diaz Guanche, Carlos; Aldana Vilas, Carlos

    2010-05-01

    Dolines are the most representative landforms of karst territories, and have a very significant development in the tropical karst. In the Sierra de los Órganos (West Cuba), the doline development in size and depth has been taken in consideration in several papers, especially after the classic works of Herbert Lehman in the 50's. Recent studies have revealed that horizontal and vertical development of doline is conditioned by tectonics, their spatial location, and is strongly controlled by the local base level. In the Sierra de Quemado, about 30 dolines were recognized with a remarkable variability in shape, size and depth. They are mainly collapsed dolines with different deepening phases, clearly marking the various evolutionary stages of the system, and working as individual entities to control the surface erosion, notably influencing the configuration of the main karst system such as the Gran Caverna de Santo Tomás. Collapse dolines originate as a consequence of the loss of mass, due to speleogenetic processes and the likely fall of the roofs of caves that developed below the dolines. The successive evolution of dolines often took place for the proximity of a cave (active or not), evolving parallelly. When doline deepening reached this level, the retraction of the walls began, which also had an influence on the hypodermic cavities observed in the dolines, and on some foot-caves ("marginal caves" or "füsshölen") that acted as important recharge points. Instability of part of the slope will cause its final collapse. Vertical jointing and faulting, together with the high values in the angles of internal friction, thoroughly contribute to the process of slope recession. Because of their different phases and evolutionary stages, the ranges in the morphometric values of dolines are high: some dolines have dimensions similar to "Tiankeng", with more than 100 metres in diameter and depth. As a rule, the different deepening phases that mark the evolutionary stages of

  17. Imagen de Hugo Chávez y su gobierno: Tomás Eloy Martínez, Mario Vargas Llosa y Carlos Fuentes

    Directory of Open Access Journals (Sweden)

    Antonio Casella

    2015-09-01

    Full Text Available El 2002 puede ser considerado un año crítico en la vida política venezolana. La promulgación inconsulta de más de 40 leyes por parte del Poder Ejecutivo a finales del año 2001 inició una sucesión de hechos que concluyeron en una huelga general que se inició en diciembre de 2002 y se suspendió al año siguiente. Estos hechos produjeron opiniones en todo el mundo. Entre tales opiniones encontramos la de tres renombrados escritores latinoamericanos: Tomás Eloy Martínez, Mario Vargas Llosa y Carlos Fuentes. El presente trabajo intenta reconstruir a partir del análisis semántico - pragmático la imagen que estos escritores poseían de Hugo Chávez y de su gobierno para ese momento. El corpus analizado lo constituyen el artículo de opinión La soga al cuello, del primer escritor mencionado; la charla titulada ¿Por qué fracasa América Latina? dictada por Vargas Llosa y una declaración de prensa ofrecida por Carlos Fuentes en Barcelona España y que el periodista tituló Carlos Fuentes no aboga por una salida militar. Estos textos fueron producidos en tres momentos diferentes de ese año y por lo tanto responden de una u otra forma a los momentos específicos en los que se produjeron.

  18. Search for evidence of trend slow-down in the long-term TOMS/SBUV total ozone data record: the importance of instrument drift uncertainty

    Directory of Open Access Journals (Sweden)

    R. S. Stolarski

    2006-01-01

    Full Text Available We have developed a merged ozone data set (MOD for the period October 1978 through June 2006 combining total ozone measurements (Version 8 retrieval from the TOMS (Nimbus 7, Earth Probe and SBUV/SBUV2 (Nimbus 7, NOAA 9/11/16 series of satellite instruments. We use the MOD data set to search for evidence of ozone recovery in response to the observed leveling off of chlorine and bromine compounds in the stratosphere. A crucial step in any time series analysis is the evaluation of uncertainties. In addition to the standard statistical time series uncertainties, we evaluate the possible instrument drift uncertainty for the MOD data set. We combine these two sources of uncertainty and apply them to a cumulative sum of residuals (CUSUM analysis for trend slow-down. For the extra-polar mean between 60° S and 60° N, the apparent slow-down in trend is found to be clearly significant if instrument uncertainties are ignored. When instrument uncertainties are added, the slow-down becomes marginally significant at the 2σ level. For the mid-latitudes of the northern hemisphere (30° to 60° N the trend slow-down is highly significant at the 2σ level, while in the southern hemisphere the trend slow-down has yet to meet the 2σ significance criterion. The rate of change of chlorine/bromine compounds is similar in both hemispheres, and we expect the ozone response to be similar in both hemispheres as well. The asymmetry in the trend slow-down between hemispheres likely reflects the influence of dynamical variability, and thus a clearly statistically significant response of total ozone to the leveling off of chlorine and bromine in the stratosphere is not yet indicated.

  19. Sistema de Información para el proceso de acreditación de la Universidad Santo Tomás de Tunja

    Directory of Open Access Journals (Sweden)

    Ivan Fernando Fonseca Barinas

    2011-05-01

    Full Text Available El Sistema de Información para el Proceso de Acreditación de la Universidad Santo Tomás es el esfuerzo de muchas personas que colaboraron en el proyecto de forma permanente, no solo para plantear una solución a la administración de la información generada en el proceso de acreditación, sino también para involucrarse realmente en el mejoramiento continuo de cada facultad y con el compromiso de alcanzar la misión de la institución. El presente trabajo detalla cómo en la etapa de diseño se modeló la realidad del proceso de acreditación con la ayuda de diferentes diagramas: diagrama arquitectónico, diagrama entidad relación y el diagrama de clases que encapsula la lógica del negocio. Al concluir el diseño se inició la tarea de implementar el sistema, para esto se utilizó el patrón Modelo Vista Controlador. En el modelo se creó la base de datos con sus tablas y atributos, así como también se crearon las clases utilizando la arquitectura JEE. Para la vista se manejó el framework de ICEfaces buscando una interfaz amigable con componentes ricos que ayudan al usuario a trabajar fácilmente en la aplicación.

  20. On Anti-slavery Thought in"Uncle Tom's Cabin"%论《汤姆叔叔的小屋》的废奴思想

    Institute of Scientific and Technical Information of China (English)

    张忆

    2015-01-01

    "Uncle Tom's Cabin"is a novel of sensation in Ameri-can literary history, not only because the sentimental novel de-picts the black reality of slavery, but also Mrs. Stowe's anti-slav-ery thought in this novel has greatly shocked the Americans and made them self-reflect on this evil system. Even though her an-ti-slavery thought has much in common with the more radical abolitionist thought at that time, they have one basic difference on how to deal with the freed black slavers. Through comparing the similarities and differences of these two thoughts, we are able to achieve a better understanding of her influence on American lit-erature and history.%《汤姆叔叔的小屋》是美国历史上一部造成轰动效应的文学作品,斯托夫人不仅在文学层面上对奴隶制的黑暗做了无情的揭露,她的废奴思想更是深深地震撼了美国人,令人反思这一邪恶的制度.她的废奴思想与当时更为激进的立即废奴思想有许多相似之处,但在如何处置获得自由的黑人这一点上有着关键的不同.探究这两种思想的异同能更好地理解她对美国文学和历史造成的无法比拟的深刻影响.林肯总统称她是"发动了一场大战的小妇人".

  1. Feasibility of using the Multinational Association of Supportive Care in Cancer Antiemesis Tool for assessment of chemotherapy-induced nausea and vomiting at the Tom Baker Cancer Centre.

    Science.gov (United States)

    Warr, Julia K; Chambers, Carole R; Cusano, Frances L; Cuthbert, Colleen A; Mah, Michelle S

    2015-10-01

    Chemotherapy-induced nausea and vomiting (CINV) has been shown to adversely impact patient anxiety, quality of life, treatment adherence, and use of health care resources. CINV control still remains a challenge, and lack of effective communication between the patient and clinician has been highlighted in the literature as the main barrier to optimal control. The Multinational Association of Supportive Care in Cancer (MASCC) has developed a tool (MASCC Antiemesis Tool (MAT)) to improve assessment and subsequent management of CINV by enhancing communication between patients and their clinicians. This study assessed the feasibility of using the MAT in patients at the Tom Baker Cancer Centre. The secondary objective was to describe the incidence of CINV as identified by the tool. This study involved a prospective survey using the MAT in patients receiving intravenous chemotherapy. Subjects completed the MAT twice post-chemotherapy regarding CINV symptoms and returned it at their next clinic appointment. Participants were also surveyed to evaluate feasibility with regard to using the MAT. Of the 50 patients recruited, 56% returned surveys. The majority of patients reported that the MAT facilitated communication with their clinician, particularly those who had experienced CINV. Fifty-four percent of patients who returned the MAT reported CINV; however, less than half of them had received American Society of Clinical Oncology-recommended antiemetic regimens. Only four patients with CINV had antiemetic changes made for subsequent cycles. The MAT is a feasible tool which can improve communication of CINV symptoms between patients and clinicians, a foundational step toward improving CINV management. © The Author(s) 2014.

  2. Phenolic characterization and variability in leaves, stems and roots of Micro-Tom and patio tomatoes, in response to nitrogen limitation.

    Science.gov (United States)

    Larbat, Romain; Paris, Cédric; Le Bot, Jacques; Adamowicz, Stéphane

    2014-07-01

    Phenolics are implicated in the defence strategies of many plant species rendering their concentration increase of putative practical interest in the field of crop protection. Little attention has been given to the nature, concentration and distribution of phenolics within vegetative organs of tomato (Solanum lycopersicum. L) as compared to fruits. In this study, we extensively characterized the phenolics in leaves, stems and roots of nine tomato cultivars using high-performance liquid chromatography coupled to electrospray ionization tandem mass spectrometry (LC-MS(n)) and assessed the impact of low nitrogen (LN) availability on their accumulation. Thirty-one phenolics from the four sub-classes, hydroxycinnamoyl esters, flavonoids, anthocyanins and phenolamides were identified, five of which had not previously been reported in these tomato organs. A higher diversity and concentration of phenolics was found in leaves than in stems and roots. The qualitative distribution of these compounds between plant organs was similar for the nine cultivars with the exception of Micro-Tom because of its significantly higher phenolic concentrations in leaves and stems as compared to roots. With few exceptions, the influence of the LN treatment on the three organs of all cultivars was to increase the concentrations of hydroxycinnamoyl esters, flavonoids and anthocyanins and to decrease those of phenolamides. This impact of LN was greater in roots than in leaves and stems. Nitrogen nutrition thus appears as a means of modulating the concentration and composition of organ phenolics and their distribution within the whole plant. Copyright © 2014 Elsevier Ireland Ltd. All rights reserved.

  3. ASK Talks with Tom Gavin

    Science.gov (United States)

    2004-01-01

    Thomas R. Gavin joined the Jet Propulsion Laboratory (JPL) in 1962. Currently the Associate Director of Flight Projects and Mission Success he has garnered a long list of engineering and management positions, including serving as mission assurance manager for both the Voyager and Galileo projects.

  4. Mount Tom Survey Summary 2003

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — This report provides recommendations regarding breeding landbirds, herpetofauna, invertebrates, and rare plant surveys and which surveys should be conducted in 2005....

  5. Estrutura do componente arbóreo em áreas de cerrado no município de São Tomé das Letras, MG

    Directory of Open Access Journals (Sweden)

    Renata de Melo Ferreira Lopes

    2013-10-01

    Full Text Available O município de São Tomé das Letras localiza-se ao sul de Minas Gerais, na bacia do rio Grande, em área de transição entre a Floresta Atlântica e o Cerrado, onde se distinguem também campos rupestres. Possui economia baseada em extrativismo mineral, agropecuária e turismo. Este trabalho teve como objetivo determinar a estrutura fitossociológica de três áreas de cerrado no município. Foram amostrados 60 pontos-quadrantes por área, tomando-se medidas de altura das árvores e circunferência de tronco (≥ 10 cm à altura do solo. Foram calculados para cada ambiente: densidade de indivíduos, dominância, frequência, área basal, Valor de Importância (VI e diversidade florística (Índice de Shannon, H'. Ao todo, foram identificadas 27 famílias, 36 gêneros e 56 espécies. Eremanthus erythropappus (candeia, Asteraceae foi a espécie de maior Valor de Importância (VI encontrada nas áreas Candeias e Vale das Borboletas e Stryphnodendron adstringens (barbatimão, Fabaceae e Piptocarpha rotundifolia (coração-de-negro, Asteraceae as espécies que se destacaram em VI na área Carrapatos. A altura média variou de 2,0 ± 1,2 a 2,3 ± 1,3m. O diâmetro médio variou de 6,5 ± 4,4 a 7,3 ± 4,8 cm. A densidade média foi de 2315 indiv.ha-1 e área basal média de 13,4 m².ha-1. O índice de diversidade de Shannon (H' para espécies variou de 2,67 a 2,96 nats/ind. Foi observada baixa similaridade de espécies entre as três áreas. Considerando as pressões antrópicas que os ambientes naturais da região vêm sofrendo, os dados obtidos poderão subsidiar projetos locais de recomposição da vegetação, principalmente do componente arbóreo.

  6. Localization of the Carnation Italian ringspot virus replication protein p36 to the mitochondrial outer membrane is mediated by an internal targeting signal and the TOM complex

    Directory of Open Access Journals (Sweden)

    Gidda Satinder K

    2008-09-01

    Full Text Available Abstract Background Carnation Italian ringspot virus (CIRV is a positive-strand RNA virus that causes massive structural alterations of mitochondria in infected host cells, the most conspicuous being the formation of numerous internal vesicles/spherules that are derived from the mitochondrial outer membrane and serve as the sites for viral RNA replication. While the membrane-bound components of the CIRV replication complex, including a 36-kD RNA-binding protein (p36, are known to be essential for these changes in mitochondrial morphology and are relatively well characterized in terms of their roles in nascent viral RNA synthesis, how these proteins are specifically targeted and inserted into mitochondria is poorly defined. Results Here we report on the molecular signal responsible for sorting p36 to the mitochondrial outer membrane. Using a combination of gain-of-function assays with portions of p36 fused to reporter proteins and domain-swapping assays with p36 and another closely-related viral RNA-binding protein, p33, that sorts specifically to the peroxisomal boundary membrane, we show that the mitochondrial targeting information in p36 resides within its two transmembrane domains (TMDs and intervening hydrophilic loop sequence. Comprehensive mutational analysis of these regions in p36 revealed that the primary targeting determinants are the moderate hydrophobicity of both TMDs and the positively-charged face of an amphipathic helix within the intervening loop sequence. We show also using bimolecular fluorescence complementation (BiFC that p36 interacts with certain components of the translocase complex in the mitochondrial outer membrane (TOM, but not with the sorting and assembly machinery (SAM. Conclusion Our results provide insight to how viruses, such as CIRV, exploit specific host-cell protein sorting pathways to facilitate their replication. The characterization of the targeting and insertion of p36 into the mitochondrial outer

  7. La historia blanqueada: representaciones de los africanos y sus descendientes en Antioquia a través de la obra de Tomás Carrasquilla

    Directory of Open Access Journals (Sweden)

    Lina del Mar Moreno Tovar

    2010-06-01

    Antioquia y a sus habitantes como correlato exitoso de la asociación entre raza blanca y montañas andinas, en contraste con valoraciones negativas sobre las tierras bajas y pobladores negros. El artículo busca por una parte examinar cuáles fueron los mecanismos de representación de los africanos y sus descendientes en Antioquia, mediante el análisis de la obra literaria de Tomás Carrasquilla y, por otra, evidenciar que esas elaboraciones marginaron los aportes de los africanos y sus descendientes a la historia antioqueña.

  8. Tropical Tropospheric Ozone (TTO) Maps from Nimbus 7 and Earth-Probe TOMS by the Modified-Residual Method. 1; Validation, Evaluation and Trends based on Atlantic Regional Time Series

    Science.gov (United States)

    Thompson, Anne M.; Hudson, Robert D.

    1998-01-01

    The well-known wave-one pattern seen in tropical total ozone [Shiotani, 1992; Ziemke et al., 1996, 1998] has been used to develop a modified-residual (MR) method for retrieving time-averaged stratospheric ozone and tropospheric ozone column amount from TOMS (Total Ozone Mapping Spectrometer) over the 14 complete calendar years of Nimbus 7 observations (1979-1992) and from TOMS on the Earth-Probe (1996-present) and ADEOS platforms (1996- 1997). Nine- to sixteen-day averaged tropical tropospheric ozone (TTO) maps, validated with ozonesondes, show a seasonality expected from dynamical and chemical influences. The maps may be viewed on a homepage: http://metosrv2.umd.edu/tropo. Stratospheric column ozone, which is also derived by the modified-residual method, compares well with sondes (to within 6-7 DU) and with stratospheric ozone column derived from other satellites (within 8-10 DU). Validation of the TTO time-series is presently limited to ozonesonde comparisons with Atlantic stations and sites on the adjacent continents (Ascension Island, Natal, Brazil; Brazzaville); for the sounding periods, TTO at all locations agrees with the sonde record to +/-7 DU. TTO time-series and the magnitude of the wave-one pattern show ENSO signals in the strongest El Nifio periods from 1979-1998. From 12degN and 12degS, zonally averaged tropospheric ozone shows no significant trend from 1980-1990. Trends are also not significant during this period in localized regions, e.g. from just west of South America across to southern Africa. This is consistent with the ozonesonde record at Natal, Brazil (the only tropical ozone data publicly available for the 1980's), which shows a not statistically significant increase. The lack of trend in tropospheric ozone agrees with a statistical analysis based on another method for deriving TTO from TOMS, the so-called Convective-Cloud-Differential approach of Ziemke et al. [1998].

  9. Basal testosterone concentrations after the application of a slow-release GnRH agonist implant are associated with a loss of response to buserelin, a short-term GnRH agonist, in the tom cat.

    Science.gov (United States)

    Goericke-Pesch, Sandra; Georgiev, Plamen; Fasulkov, Ivan; Vodenicharov, Angel; Wehrend, Axel

    2013-07-01

    Slow-release GnRH agonist implants are considered an effective, reversible alternative to surgical castration in male tom cats. Individual differences exist regarding the onset of efficacy and might be delayed in some animals. Single measurements of testosterone (T) might result in basal concentrations also in intact male cats. Consequently, GnRH stimulation tests are performed to measure T increase in intact animals and to differentiate castrated from intact male cats. In this study, five tom cats were treated with a 4.7-mg deslorelin implant and GnRH stimulation tests using buserelin were performed before treatment and at 4-week intervals afterward until Week 20. After the last test in Week 20 all animals were castrated. Four of five animals had basal T after 4 weeks and-in contrast to pretreatment-application of buserelin did not result in any further T increase. In one animal, T was low after implant insertion, but not basal; however, a GnRH stimulation test induced a slight increase of T in Week 8 and 16 only and no response in Weeks 4, 12, and 20. Testicular volume was significantly decreased and penile spines disappeared in all cats. Testicular histology showed mixed atrophy, but also fully elongated spermatids in three of five male cats making infertility questionable. Because of the loss of the stimulatory effect of short-term GnRH application (buserelin), it can be assumed that long-term GnRH agonists also act by some mechanisms of downregulation of pituitary GnRH receptors in the tom cat. Copyright © 2013 Elsevier Inc. All rights reserved.

  10. Green, Gray and White. Nature and Architecture in the Maps of Catastro de Ensenada and the sketches of Diccionario Geográfico by Tomás López

    Directory of Open Access Journals (Sweden)

    María José ORTEGA CHINCHILLA

    2017-02-01

    Full Text Available As opposed to the grey line that defines public and private space of cohabitation, and the colour white that takes us to marginal, unproductive or inaccessible spaces, we find in these images the colour green as an expression of that remote sensibility –almost magical– which links man with nature. The study of the colour, lines and composition of the maps that appear in the Respuestas Generales of the Catastro de Ensenada and the sketches sent by the pastors of the different Spanish cities to the geographer Tomás López, in this article I analyse.

  11. Autorregulación e integración: dos propuestas en la educación de la afectividad (D. Goleman y Tomás de Aquino)

    OpenAIRE

    Altarejos, F. (Francisco)

    2004-01-01

    La propuesta de D. Goleman sobre la inteligencia emocional tiene implicaciones directas en la educación de la afectividad. La visión clásica de la afectividad, resumida en la doctrina de Tomás de Aquino, presenta discrepancias y semejanzas con la concepción de la inteligencia emocional de Goleman. Son dos propuestas contrarias, pero no contradictorias. No se anulan una a otra, pero tampoco son complementarias: se debe optar entre una u otra para mantener la unidad de sent...

  12. São Tomé and Príncipe; Staff Report for the 1999 Article IV Consultation and Request for an Arrangement Under the Poverty Reduction and Growth Facility

    OpenAIRE

    International Monetary Fund

    2000-01-01

    In the fiscal area, the primary budget balance of São Tomé and Príncipe has turned around from a deficit of 2.2 percent of GDP in 1997 to a surplus of 0.7 percent of GDP in 1998 (Dobra 1.9 billion). The primary surplus is estimated to have increased further to 1.3 percent of GDP in 1999. Monetary policy has remained tight in 1999, as the central bank has maintained the reserve requirement ratio at 22 percent and commercial banks have kept their savings and lending rates substantially above th...

  13. A água e o vinho: a recepção das teorias aristotélicas da linguagem na doutrina de São Tomás de Aquino sobre o Verbo

    OpenAIRE

    Fedeli, Maria Ivone Pereira de Miranda

    2017-01-01

    Este trabalho procura mostrar como, ao longo de seu percurso intelectual, São Tomás de Aquino vai, a partir de uma dúvida inicial sobre a possibilidade de compatibilidade da terminologia teológica sobre o Verbo Divino, baseada no Prólogo do Evangelho de São João e consolidada por Santo Agostinho no De Trinitate, com os conceitos sobre o verbo humano formulados por Aristóteles no De Anima, no Peri Hermeneias e demais textos sobre a linguagem humana, chegar a harmonizar a ambos, sem abandonar a...

  14. Riesgo de la delincuencia en Chile. Estudio de caso en el marco de proyectos situacionales de recuperación de espacios públicos en la comuna de Tomé

    OpenAIRE

    Ximena Martínez

    2014-01-01

    El objetivo del presente trabajo es expon er los resultados de una investigación realizada con el propósito de conocer los efectos de dos Intervenciones Situacionales de Recuperación de Espacios Públicos para la prevención del delito en Chile, específicamente en la comuna de Tomé, financiados por el Ministerio del Interior y Seguridad Pública. Como parte de la metodología del estudio se llevó a cabo un trabajo de campo donde los beneficiaros, a través de una pauta de preguntas abiertas, daban...

  15. Memória e tradição nos dramas de São Tomé e Príncipe e Angola: os teatros de Fernando de Macedo e José Mena Abrantes

    OpenAIRE

    Éboli, Luciana Morteo

    2010-01-01

    O presente trabalho analisa, sob o ponto de vista mítico, seis textos representativos da dramaturgia africana de língua portuguesa da atualidade: O rei do obó (1999), Capitango (1998) e Cloçon Son (1997), do dramaturgo Fernando de Macedo, de São Tomé e Príncipe, e Nandyala ou a tirania dos monstros (1985), Na Nzuá e Amirá ou de como o prodigioso filho de Na Kimanaueze se casou com a filha do Sol e da Lua (1998) e Pedro Andrade, a tartaruga e o gigante (1989), do dramaturgo José Mena Abrantes,...

  16. Prevalencia de hipertensión arterial, proporción de hipertensos que lo desconocen y algunos posibles factores de riesgo asociados, en el Municipio de Santo Tomás – Atlántico / Prevalence of high blood pressure, percentage of the people who have no knowledge of it, and some associated factors of risk in Municipio de Santo Tomás, Atlántico

    OpenAIRE

    Donado Badillo, Enrique Manuel

    2010-01-01

    Objetivo. Determinar la prevalencia de hipertensión arterial, proporción de las personas que lo desconocen, y algunos posibles factores de riesgo asociados en el municipio de Santo Tomás, Atlántico (Colombia) entre noviembre de 2008 y enero de 2009. Métodos. Estudio de corte transversal, de base poblacional encuestando a una muestra aleatoria de 244 personas mayores de 18 años para obtener información sociodemográfica, estado de aseguramiento, antecedentes familiares dentro del primer...

  17. Prevalencia de hipertensión arterial, proporción de hipertensos que lo desconocen y algunos posibles factores de riesgo asociados, en el Municipio de Santo Tomás – Atlántico / Prevalence of high blood pressure, percentage of the people who have no knowledge of it, and some associated factors of risk in Municipio de Santo Tomás, Atlántico

    OpenAIRE

    Donado Badillo, Enrique Manuel

    2010-01-01

    Objetivo. Determinar la prevalencia de hipertensión arterial, proporción de las personas que lo desconocen, y algunos posibles factores de riesgo asociados en el municipio de Santo Tomás, Atlántico (Colombia) entre noviembre de 2008 y enero de 2009. Métodos. Estudio de corte transversal, de base poblacional encuestando a una muestra aleatoria de 244 personas mayores de 18 años para obtener información sociodemográfica, estado de aseguramiento, antecedentes familiares dentro del primer...

  18. Novel analytical model for predicting the combustion characteristics of premixed flame propagation in lycopodium dust particles

    Energy Technology Data Exchange (ETDEWEB)

    Bidabadi, Mehdi; Rahbari, Alireza [Iran University of Science and Technology, Tehran (Iran, Islamic Republic of)

    2009-09-15

    This paper presents the effects of the temperature difference between gas and particle, different Lewis numbers, and heat loss from the walls in the structure of premixed flames propagation in a combustible system containing uniformly distributed volatile fuel particles in an oxidizing gas mixture. It is assumed that the fuel particles vaporize first to yield a gaseous fuel, which is oxidized in a gas phase. The analysis is performed in the asymptotic limit, where the value of the characteristic Zeldovich number is large. The structure of the flame is composed of a preheat zone, reaction zone, and convection zone. The governing equations and required boundary conditions are applied in each zone, and an analytical method is used for solving these equations. The obtained results illustrate the effects of the above parameters on the variations of the dimensionless temperature, particle mass friction, flame temperature, and burning velocity for gas and particle

  19. Cyclobutane Synthesis and Fragmentation. A Cascade Route to the Lycopodium Alkaloid (-)-Huperzine A.

    Science.gov (United States)

    White, James D; Li, Yang; Kim, Jungchul; Terinek, Miroslav

    2015-12-04

    An asymmetric total synthesis of the nootropic alkaloid (-)-huperzine A was completed using a cascade sequence initiated by an intramolecular aza-Prins reaction and terminated by a stereoelectronically guided fragmentation of a cyclobutylcarbinyl cation as the key step in assembling the bicyclo[3.3.1]nonene core of the natural product. Intramolecular [2 + 2]-photocycloaddition of the crotyl ether of (S)-4-hydroxycyclohex-2-enone afforded a bicyclo[4.2.0]octanone containing an embedded tetrahydrofuran in which the cyclohexanone moiety was converted to a triisopropylsilyl enol ether and functionalized as an allylic azide. The derived primary amine was acylated with α-phenylselenylacrylic acid, and the resulting amide was reacted with trimethylaluminum to give a [2 + 2]-cycloadduct, which underwent retroaldol fission to produce a fused α-phenylselenyl δ-lactam. Periodate oxidation of this lactam led directly to an α-pyridone, which was converted to a fused 2-methoxypyridine. Reductive cleavage of the activated "pyridylic" C-O bond in this tetracycle and elaboration of the resultant hydroxy ketone to a diketone was followed by chemoselective conversion of the methyl ketone in this structure to an endo isopropenyl group. Condensation of the remaining ketone with methyl carbamate in the presence of acid initiated the programmed cascade sequence and furnished a known synthetic precursor to huperzine A. Subsequent demethylation of the carbamate and the methoxypyridine, accompanied by in situ decarboxylation of the intermediate carbamic acid, gave (-)-huperzine A.

  20. 'Verdadero es lo que es' En torno a la verdad ontológica según Tomás de Aquino (De Veritate q. l, a. l

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    Luis Bacigalupo

    1989-12-01

    Full Text Available Este artículo presupone que el problema de la verdad ontológica es un auténtico problema filosófico; pero lo entiende como la cuestión de determinar el nexo entre la verdad proposicional y la 'cosa' por ella referida. Tomás de Aquino se enfrenta magistralmente a este problema; pero lo plantea de una manera insatisfactoria para una aproximación no metafísica al mismo. Sin embargo, su planteamiento es importante toda vez que señala claramente que el núcleo de la cuestión relativa a la 'verdad' estriba en las peculiaridades del lenguaje que aparecen como 'suposición', 'referencia', 'significación'. El desarrollo de lo esbozado por Tomás es el punto de partida para el tratamiento del terna en el marco de la teoría medieval de la suposición.

  1. The Song of the Sabia in the 3rd. Festival Internacional da Canção: boo and sunset of the Tom Jobim bossa nova`s aesthetics

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    Fabio Guilherme Poletto

    2015-07-01

    Full Text Available This article discusses the Song of the Sabia, composition of Tom Jobim and Chico Buarque. Mobilizes different series of sources in order to reconstruct historically the boo to the performance of the song during the III International Song Festival, held in 1968 in the city of Rio de Janeiro. Seeks to highlight how this episode catalyzed the existence of different expectations on the popular song and its role as a vehicle for ideals of modernity amid the interference of the authoritarian environment in the cultural and political field. Then, based on the analysis of the constitutive parameters of the song, suggests possibilities for understanding its musical and poetic construction in critical dialogue with its reverberations in cultural terms.This article discusses the Song of the Sabia, composition of Tom Jobim and Chico Buarque. Mobilizes different series of sources in order to reconstruct historically the boo to the performance of the song during the III International Song Festival, held in 1968 in the city of Rio de Janeiro. Seeks to highlight how this episode catalyzed the existence of different expectations on the popular song and its role as a vehicle for ideals of modernity amid the interference of the authoritarian environment in the cultural and political field. Then, based on the analysis of the constitutive parameters of the song, suggests possibilities for understanding its musical and poetic construction in critical dialogue with its reverberations in cultural terms.

  2. Contribución a la historia de la liberta de expresión parlamentaria: el discurso de Tomás Moro como Speaker del Parlamento inglés de 1523

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    Hernán Corral Talciani

    2011-01-01

    un Congreso o Parlamento es la inviolabilidad o irresponsabilidad por las opiniones o expresiones emitidas en el ejercicio de sus cargos. El presente trabajo indaga en el reconocimiento constitucional de esta libertad de expresión en el Derecho parlamentario inglés y en la influencia de un discurso pronunciado por el jurista, humanista y hombre público del siglo XVI, Tomás Moro, como Speaker del Parlamento convocado por Enrique VIII en 1523, que se ha conservado gracias a su primera biografía redactada por su yerno, William Roper. Se concluye que, aunque no pueda decirse que Tomás Moro sea el fundador de esta prerrogativa parlamentaria, debe reconocérsele el mérito de haber contribuido a su posterior consagración con sus habilidades tanto retóricas como argumentativas, según se aprecia en el discurso. Como anexo, se ofrece una traducción al español del texto analizado.

  3. Tropical tropospheric ozone (TTO) maps from Nimbus 7 and Earth Probe TOMS by the modified-residual method: Evaluation with sondes, ENSO signals, and trends from Atlantic regional time series

    Science.gov (United States)

    Thompson, Anne M.; Hudson, Robert D.

    1999-11-01

    The modified-residual (MR) method for retrieving time-averaged stratospheric ozone and tropospheric ozone column amounts from the Total Ozone Mapping Spectrometer (TOMS) is applied to the 14 complete calendar years of Nimbus 7 observations (1979-1992). These are available as digital data at http://metosrv2.umd.edu/˜tropo/14y_data.d The MR method has also been used to produce real-time maps of tropical tropospheric ozone (TTO) from TOMS on the Earth-Probe (1996-present) and ADEOS platforms (1996-1997). Evaluation of the TTO time series for 1979-1990 and 1997-1998 is presented here; it is limited to the few tropical ozonesonde stations operational during those years (Ascension Island; Natal, Brazil; Brazzaville). The standard deviation of the differences between TTO and the sondes is ±(6-7) Dobson units (DU), depending on location. Stratospheric column ozone, which is also derived by the modified-residual method, compares favorably with sondes (to within 6-9 DU) and with stratospheric ozone inferred from other satellites (usually 8-15 DU lower than the latter). TTO time series and the magnitude of the tropospheric wave-one pattern show El Niño-Southern Oscillation (ENSO) signals during the period from 1979-1992. During 1997 the ENSO stands out at some stations, but not at others. Between 12°N and 12°S, zonally averaged TTO shows no significant trend from 1980-1990. Trends are also not significant during this period in localized regions, for example, from just west of South America across to southern Africa. This is consistent with the ozonesonde record at Natal, Brazil (the only tropical ozone data publicly available for the 1980s), which shows no significant trend. The lack of trend in tropospheric ozone agrees with a statistical analysis based on another method for deriving TTO from TOMS, the convective-cloud-differential approach of Ziemke et al. [1998].

  4. (Re)viver as roças: reabilitação participada das roças de São Tomé e Príncipe

    OpenAIRE

    Vicente, Marta Alexandra Gonçalves

    2016-01-01

    A investigação (Re)Viver as roças – Reabilitação participada das roças de São Tomé e Príncipe, surge no âmbito de uma dissertação de natureza científica, tendo como objetivo central o desenho e implementação de uma primeira fase de um processo participado de reabilitação das roças, promovendo o envolvimento direto e ativo das comunidades locais nos processos de tomada de decisões sobre o espaço que habitam. O tema surge como uma oportunidade de procurar uma resposta para o atual e...

  5. Riesgo de la delincuencia en Chile. Estudio de caso en el marco de proyectos situacionales de recuperación de espacios públicos en la comuna de Tomé

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    Ximena Martínez

    2014-01-01

    Full Text Available El objetivo del presente trabajo es expon er los resultados de una investigación realizada con el propósito de conocer los efectos de dos Intervenciones Situacionales de Recuperación de Espacios Públicos para la prevención del delito en Chile, específicamente en la comuna de Tomé, financiados por el Ministerio del Interior y Seguridad Pública. Como parte de la metodología del estudio se llevó a cabo un trabajo de campo donde los beneficiaros, a través de una pauta de preguntas abiertas, daban su opinión respecto del proyecto situacional cercano a s u hogar, pudiendo de esta forma evaluarse cualitativamente una po - lítica pública en materia de seguridad. El presente trabajo analiza estos resultados y presenta conclusio - nes respecto de este tipo de intervenciones.

  6. Recepción de la física de Aristóteles por Tomás de Aquino: finitud, necesidad, vacío, unicidad del mundo y eternidad del universo

    OpenAIRE

    Minecan, Ana Maria Carmen

    2015-01-01

    La tesis doctoral analiza el proceso de recepción y condena de la física de Aristóteles en el siglo XIII así como su asimilación en la obra de Tomás de Aquino, a la luz de los nuevos textos disponibles y desde una perspectiva en la que se pretende poner en énfasis la vigencia filosófica de gran parte de los problemas y cuestiones debatidas en este periodo. Ofrecemos asimismo un análisis detallado de los cambios sufridos por la concepción del cosmos medieval tras la recuperación del legado fís...

  7. Presentación clínica de tuberculosis en pacientes VIH+ atendidos en el Hospital Santo Tomás, Panamá. Enero a julio del 2009

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    Bernardino Denis

    2010-01-01

    Full Text Available Objetivo: describir las presentaciones clínicas de la tuberculosis en los pacientes VIH+ atendidos en el Hospital Santo Tomás de enero a julio de 2009. Metodología: se trata de un estudio descriptivo retrospectivo que consistió en la revisión de expedientes clínicos de los pacientes que presentaron coinfección de tuberculosis y VIH en el Hospital Santo Tomás durante el primer semestre del año 2009. Se analizó el universo de pacientes. Se utilizó un formulario para la recolección de los datos y para el análisis de los datos se calcularon frecuencias, modas, medianas y promedios. Se utilizo el programa EpiInfo 3.5.1 y se realizaron los gráficos con Microsoft Office Excel. Resultados: La relación hombres : mujeres fue de 3 : 1. Se observó una mayor frecuencia de pacientes procedentes del corregimiento de Juan Díaz (13,5% Calidonia (10,4% Santa Ana (10,4%. La presentación clínica predominante fue la pulmonar (64,4% seguida por la mixta (20% y la extrapulmonar (15,6%; entre las formas extrapulmonares la más frecuente fue la ganglionar (37,5%. Conclusiones: La presentación clínica pulmonar reporta es de 64,4%; extrapulmonar, 15,6%; y mixta, 20,0%. Entre las presentaciones extrapulmonares, la presentación ganglionar se reporta en 37,5%. El método clínico radiológico es el medio diagnóstico más usado (76% a diferencia de otros estudios.

  8. La sillería del coro del desaparecido convento de Santo Tomás de Aquino (Madrid: un trabajo germinal y olvidado de José Benito Churriguera

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    González Santos, Javier

    2014-03-01

    Full Text Available This article presents a juvenile work by José Benito Churriguera (1665-1725: the choir stalls of the now-disappeared convent of Saint Thomas Aquinas (Order of Preachers in Madrid, carved in 1688-1691 and apparently destroyed in 1872. The reference was published in Vida, virtudes y exercicios del Illmo. y Revmo. Sr. D. F. Thomás Reluz, obispo de Oviedo (Life, virtues and exercises of His Grace Thomas Reluz, bishop of Oviedo, by Friar Manuel José de Medrano, a rare edition published in Oviedo in 1718. During this research the relationship of the Churrigueras with the Dominicans and Bishop Reluz has been examined, allowing for the clarification of the circumstances of the involvement of José Benito and his sons in the architectural works of this convent, which traditionally has been attributed to them.Se da noticia de un trabajo juvenil de José Benito Churriguera (1665-1725: la sillería del coro del desaparecido convento de Santo Tomás de Aquino (orden de Predicadores de Madrid, labrada en 1688-1691 y destruida, al parecer, en 1872. La referencia está publicada en la Vida, virtudes y exercicios del Illmo. y Revmo. Sr. D. F. Thomás Reluz, obispo de Oviedo, escrita por fray Manuel José de Medrano, un raro impreso publicado en Oviedo en 1718. Al hilo de esta investigación hemos estudiado la relación de los Churriguera con los dominicos y el obispo Reluz, lo que ha permitido puntualizar algunos extremos y circunstancias de la intervención de José Benito y sus hijos en las obras arquitectónicas del madrileño convento de Santo Tomás que venía siéndoles atribuida.

  9. Tomás de Aquino, Anselmo de Canterbury e a crítica da razão teológica - doi: 10.4025/actascieduc.v32i1.9487

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    Jean Lauand

    2010-08-01

    Full Text Available Normal 0 21 false false false MicrosoftInternetExplorer4 /* Style Definitions */ table.MsoNormalTable {mso-style-name:"Tabela normal"; mso-tstyle-rowband-size:0; mso-tstyle-colband-size:0; mso-style-noshow:yes; mso-style-parent:""; mso-padding-alt:0cm 5.4pt 0cm 5.4pt; mso-para-margin:0cm; mso-para-margin-bottom:.0001pt; mso-pagination:widow-orphan; font-size:10.0pt; font-family:"Times New Roman"; mso-ansi-language:#0400; mso-fareast-language:#0400; mso-bidi-language:#0400;} Em 2009 se comemorou o 9º. centenário da morte de S. Anselmo (1033-1109. O artigo examina sua proposta de Teologia como ciência em contraste com a de Tomás de Aquino (1125-1274: as "rationes necessariae" anselmianas - no caso da Teologia da Redenção no "Cur Deus Homo?" - são confrontadas com as do Aquinate, contextualizadas pelo quadro geral do pensamento de Tomás.   Normal 0 21 false false false MicrosoftInternetExplorer4 Normal 0 21 false false false MicrosoftInternetExplorer4 /* Style Definitions */ table.MsoNormalTable {mso-style-name:"Tabela normal"; mso-tstyle-rowband-size:0; mso-tstyle-colband-size:0; mso-style-noshow:yes; mso-style-parent:""; mso-padding-alt:0cm 5.4pt 0cm 5.4pt; mso-para-margin:0cm; mso-para-margin-bottom:.0001pt; mso-pagination:widow-orphan; font-size:10.0pt; font-family:"Times New Roman"; mso-ansi-language:#0400; mso-fareast-language:#0400; mso-bidi-language:#0400;}

  10. Nota sobre a variação sazonal da circulação geostrófica na borda da plataforma continental: Cabo de São Tomé (RJ e a Baía de Guanabara (RJ Seasonal variation of geostrophic circulation on the continental slope: Cape of São Tomé (RJ and Guanabara Bay (RJ

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    Ademildes Maria Paviglione

    1985-01-01

    Full Text Available Cinco observações oceanográficas espaciais quase sinóticas, realizadas de janeiro de 1970 a fevereiro de 1971, na região entre o Cabo de São Tomé e a Baía de Guanabara, são usadas para descrever a circulação sazonal e as condições de fluxo da Corrente do Brasil próximo à plataforma continental. As velocidades relativas foram calculadas sobre superfícies isanostéricas, de acordo com o método sugerido por Montgomery (1937. A precisão do método foi analisada, com base na propagação dos erros instrumentais das medidas da temperatura, da salinidade e da profundidade sobre o volume específico e a aceleração potencial, obtendo-se uma precisão de cerca de ± 3,0 cm s-1, para a velocidade relativa, e um máximo de ± 2,5 Sv, para o transporte de volume através da secção transversal. As correntes geostróficas de superfície, calculadas com referência à superfície isanostérica de 100 cl ton-1, sao geralmente mais intensas através das secções a leste de Cabo Frio, onde elas atingem valores máximos (~90 cm s-1 na borda da plataforma continental durante o verão, e valores acima de 86 cm s-1 ocorrem no inverno, mais além, a distâncias da costa maiores do que 140 km. Os diagramas T-S mostram os detalhes da distribuição do fluxo nas classes características e o fato de que 50% do transporte total corresponde à Massa de Água Tropical, próxima da superfície isanostérica de 220 cl ton-1. As variações do transporte total na coluna de água, desde a superfície até a superfície isanostérica de referência, foram analisadas para estimar o transporte por unidade de largura.Five-nearly-synoptic spatial oceanographic observations, taken from January, 1970 to February, 1971, in the region between Cape of São Tomé and Guanabara Bay, are used to describe the seasonal circulation and flow conditions of the Brazil Current, close to the continental slope. The relative geostrophic velocities were calculated over isanosteric

  11. Brad Patterson, Tom Brooking, and Jim McAloon, Unpacking the Kist: The Scots in New Zealand. McGill-Queen's Studies in Ethnic History Series, No. 2.33. Montreal: McGill-Queen’s University Press, 2013. Pp. 412. ISBN 978-0-7735-4190-0. CAD $100.00.

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    Seán Gerard Brosnahan

    2014-11-01

    Full Text Available Brad Patterson, Tom Brooking, and Jim McAloon, Unpacking the Kist: The Scots in New Zealand. McGill-Queen's Studies in Ethnic History Series, No. 2.33. Montreal: McGill-Queen’s University Press, 2013. Pp. 412. ISBN 978-0-7735-4190-0. CAD $100.00.

  12. Arquitectura, urbanismo y obras públicas civiles y militares en el Atlas Geográfico de España de Tomás López de 1804

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    San-Antonio-Gómez, C.

    2016-06-01

    Full Text Available This manuscript presents a novel analysis that deals about how architecture, urban planning and civil and military public works are represented in Geographic Atlas of Spain 1804 (AGE of Tomas Lopez. For this it has been characterized different map symbols appearing on maps, which are the benchmarks for analysis and transmit accurate information on the shape and meaning of what is represented. So, more than one hundred different symbols were found. This gives an idea of the great detail and richness of the information contained in AGE. A deeper analysis shows that eighteen of them are equivalent to other previous cartographic symbols. These were from Chevalier, D’Anville teacher, who in turn was the teacher Thomas Lopez in Paris. Additionally, we found that there are several symbols with similarity to their corresponding of the Ordinances of the Royal Corps of Engineers from 1803.El objetivo que planteamos es analizar cómo Tomás López representó en su Atlas Geográfico de España (AGE de 1804, la arquitectura, el urbanismo y las obras públicas civiles y militares, un análisis hasta el momento inédito. Para ello se han caracterizado los diferentes símbolos cartográficos que aparecen en los mapas, que constituyen los parámetros de referencia del análisis y transmiten información fidedigna de la forma y significado de lo representado. Para esas tipologías se han encontrado ciento trece símbolos diferentes, lo que da idea de la minuciosidad y riqueza de la información contenida en los mapas. Dieciocho de ellos, son equivalentes con otros tantos símbolos cartográficos de Chevalier, maestro de D’Anville, de quien Tomás López fue discípulo en París. También hay una similitud entre cuatro símbolos del AGE con sus correspondientes signos de las Ordenanzas del Real Cuerpo de Ingenieros de 1803.

  13. Contribuição ao estudo da circulação e do transporte de volume da corrente do Brasil entre o Cabo de São Tomé e a Baía de Guanabara Contribution to the studies of transport and circulation of the Brazil current in the are a between Cabo de São Tomé and Guanabara Bay

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    Sérgio R Signorini

    1976-01-01

    Full Text Available Tal estudo teve por finalidade avaliar a velocidade e o transporte de volume da Corrente do Brasil, no seu trecho entre Cabo de São Tomé e Cabo Frio, fazendo uso do calculo geostrofico aplicado às secções amostradas durante os cruzeiros de abril e julho de 1970 e de julho de 1973. Foram localizados dois vórtices anticiclônicos, um durante o período de abril de 1970 e o outro durante julho de 1973. O valor máximo de velocidade da corrente na superfície foi de aproximadamente 70 cm/s e o transporte de volume foi de 14 x 10(6 m³/s. Foi possível também confirmar a existência de um meandro da Corrente do Brasil através da utilização de uma secção de BT (batitermografo mecânico associada a um registro contínuo de salinidade e de temperatura obtido com um termosalinografo.During the periods of April, July, 1970 and July, 1973, océanographic cruises were conducted in order to investigate the variability of the Brazil Current in the region between Cabo de Sao Tomé and Guanabara Bay. The geostrophic model of ocean circulation was applied using the hydrographie data collected during the cruise. From this study, a maximum velocity of 70 cm/sec and a volume trans port of 14 x 10(6 m³/sec were reported. The dynamic topography with reference to the 500 db surface, showed the presence of anticyclonic eddies during the periods of April, 1970, and July, 1973. The thermohaline structure within a meander of the Brazil Current is also presented utilizing the data coming from a continuous salinity and temperature recorder in conection with the data coming from a simultaneous BT section.

  14. Tecnogénesis. La construcción técnica de las ecologías humanas (2 Volúmenes (Tomás Sánchez-Criado, Ed.

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    Pablo Santoro

    2009-05-01

    Full Text Available De ser necesaria una aproximación radicalmente reduccionista a un trabajo tan poliédrico, creo que podría resumirse parte del mensaje de Tecnogénesis. La construcción técnica de las ecologías humanas, la ambiciosa obra colectiva editada por Tomás Sánchez Criado, en dos de sus comienzos. El primero es el que abre el breve y hermoso preámbulo escrito por Florentino Blanco: una reflexión, al hilo de la asistencia del autor a un concierto de música vocal contemporánea, sobre la profunda modificación de la gramática musical clásica en la experimentación actual y sobre la confusión cognitiva y emocional a la que esta destrucción de los códigos acostumbrados arroja al espectador.

  15. Tomás de Suria, un dibujante de la expedición de Malaspina. Su contribución al conocimiento del occidente de Norteamérica

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    Jiménez Pelayo, Águeda

    1997-12-01

    Full Text Available Not available.

    Este trabajo está dedicado a destacar el papel de Tomás de Suria, dibujante de la Academia de San Carlos de la ciudad de México, en la expedición de Alejandro Malaspina. Se hacen algunas referencias al viaje alrededor del mundo y trata especialmente de las investigaciones realizadas en las costas de Canadá y Alaska. Se da énfasis a la importancia de la labor de los artistas para el conocimiento de los lugares visitados, centrándose en la obra artística de Suria. Comprende un análisis de la contribución de Suria como dibujante y las penalidades que tuvo que soportar para que su trabajo fuera reconocido. Se aprovecha también la valiosa información que proporciona Suria acerca de las costumbres de los nativos de Mulgrave y Nutka, pues con ella se enriquece la antropología y etnohistoria de estas regiones. A través de los dibujos de los artistas de la expedición tenemos un mejor conocimiento de la cartografía, geografía, geodesia, botánica, zoología y etnohistoria del noroeste de América.

  16. Martinho Lutero (1483-1546 e Tomás Müntzer (1489-1525: a justificação teológica da autoridade secular e da revolução política

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    Dreher, Martin Norberto

    2006-01-01

    Full Text Available A Reforma em território alemão possui duas figuras, por vezes próximas entre si, por vezes muito distantes: Lutero e Tomás Müntzer. À medida que foi se envolvendo na vida de seus fiéis, Müntzer foi tomando caminhos próprios, discordando de Lutero que este tomava a "Palavra, em sua realidade objetiva, como constitutiva da Igreja, e afirmando que os verdadeiros fiéis são os que possuem a experiência subjetiva do "Espírito". Também contra Lutero, que defende a resistência à autoridade, mas em questões seculares aceita a tirania, Müntzer, que vê a fé fortemente inserida no social, defende a revolução armada contra os príncipes. Müntzer não nega a graça, mas esta possui papel secundário em seu pensamento, enquanto, para Lutero, ela se coloca no centro de suas preocupações teológicas

  17. 菲尔丁《汤姆·琼斯》典故网中的文化“肴馔”%The “Feast” of Culture in the Networks of Allusion in Henry Fielding's Tom Jones

    Institute of Scientific and Technical Information of China (English)

    张杨莉

    2013-01-01

    研究亨利·菲尔丁《汤姆·琼斯》典故网中的文化主题,分析菲尔丁如何网状般地构造其笑、打、美、醉、怒典故网及其在文化主题中所起到的多种作用。典故网的叙述方式间接地表达了小说家的思想与观点,表现了其叙述的艺术特征,唤起了读者的想象力,为读者带来了愉悦的文化“肴馔”享受。%This article studies the cultural theme in the networks of allusion used in Henry Fielding's Tom Jones, and analyzes how Fielding constructs the networks of allusion concerning smile, whipping,beauty, drunkenness and fury, which achieve various cultural functions. The narrative method of the networks of allusion indirectly expresses the novelist's ideas and views, illustrates the artistic features of the narration, evokes the reader's imagination and offers the reader the pleasure of appreciating the“feast” of culture.

  18. Antropologia e teologia na noção de sacrifício em santo tomás de aquino = Antropology and theology in Saint Thomas’s notion of sacrifice

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    Fornasier, Rafael Cerqueira

    2013-01-01

    Full Text Available Através de breve e, ao mesmo tempo, cuidadoso exame da Suma Teológica de Santo Tomás de Aquino, este artigo visa colocar em evidência como o autor, ao tratar da noção de sacrifício em várias partes da obra, permite discernir uma compreensão aprofundada do mesmo, dando um enfoque não somente teológico, mas também antropológico. Ao se evidenciar a estreita relação destes dois aspectos, propõe-se haurir da reflexão o profundo nexo entre a atitude humana em oferecer sacrifício a Deus e o único sacrifício de Cristo, como perfeita expressão humana de comunhão com Deus, realizado uma vez por todas e sem cessar celebrado na Eucaristia

  19. Giardia duodenalis and soil-transmitted helminths infections in children in São Tomé and Príncipe: do we think Giardia when addressing parasite control?

    Science.gov (United States)

    Ferreira, Filipa Santana; Baptista-Fernandes, Teresa; Oliveira, Dinamene; Rodrigues, Rúben; Neves, Edgar; Lima, António; Garrido, Eduardo; Afonso, Guilherme; Zaky, Ahmed; Telles de Freitas, Paulo; Atouguia, Jorge; Centeno-Lima, Sónia

    2015-04-01

    Giardia duodenalis prevalence is commonly as high as soil-transmitted helminths (STH), nevertheless is not considered for large-scale chemotherapy through mass drug administration (MDA) due to its short incubation period and frequent reinfections, its control being associated to improving access to water and sanitation. A study enrolling 444 children attending preschools was conducted in May 2011 during a deworming campaign. Faecal samples were obtained and analysed through microscopy of wet mounting and after Kato-Katz and formol-ether concentration techniques. The majority of children were infected with at least one pathogenic parasite (86.7%, 385 of 444). Ascaris lumbricoides and Trichuris trichiura (56.3%, 250 of 444 and 52.5%, 233 of 444, respectively) were the most frequent parasites followed by G. duodenalis infecting 41.7% (185 of 444) of the children. The present work aimed at obtaining updated information concerning intestinal parasite infections in children attending preschools in São Tomé and Príncipe and to contribute for the adequate management of the enteric infections.

  20. Review of Selected References and Data sets on Ambient Ground- and Surface-Water Quality in the Metedeconk River, Toms River, and Kettle Creek Basins, New Jersey, 1980-2001

    Science.gov (United States)

    Nicholson, Robert S.; Hunchak-Kariouk, Kathryn; Cauller, Stephen J.

    2003-01-01

    Surface water and ground water from unconfined aquifers are the primary sources of drinking water for much of the population, about 391,000, in the Metedeconk River, Toms River, and Kettle Creek watersheds in the New Jersey Coastal Plain. The quality of these sources of drinking water is a concern because they are vulnerable to contamination. Indications of the occurrence, distribution, and likely sources and transport mechanisms of certain contaminants were obtained from 48 selected reports and 2 selected data sets on water quality in or near the watersheds (1980-2001). These indications are described and briefly summarized in this report. The findings of studies on ground-water quality indicate that shallow ground water within the study area generally meets primary drinking-water standards, with notable exceptions. Volatile organic compounds, mercury, arsenic, radionuclides, nitrate, and coliform bacteria have been detected in shallow ground water in some areas at levels that exceed Federal and State drinking-water standards. For example, results of analyses of untreated samples collected from more than 13,000 private wells during 1983-99 indicated that concentrations of volatile organic compounds in samples from 7.3 percent of the wells exceeded at least 1 of 11 drinking-water standards, according to records maintained by the Ocean County Health Department. In cases of exceedances, however, water treatment, well replacement, and (or) retesting assured that applicable drinking-water standards were being met at the tap. Reported concentrations of the pesticide chlordane in some areas exceeded the drinking-water standard; few data are available on the occurrence of other pesticides. Studies of nearby areas, however, indicate that pesticide concentrations generally could be expected to be below drinking-water standards. The combination of low pH and low dissolved solids in many areas results in shallow ground water that is highly corrosive and, if untreated, able to

  1. Review of Selected References and Data sets on Ambient Ground- and Surface-Water Quality in the Metedeconk River, Toms River, and Kettle Creek Basins, New Jersey, 1980-2001

    Science.gov (United States)

    Nicholson, Robert S.; Hunchak-Kariouk, Kathryn; Cauller, Stephen J.

    2003-01-01

    Surface water and ground water from unconfined aquifers are the primary sources of drinking water for much of the population, about 391,000, in the Metedeconk River, Toms River, and Kettle Creek watersheds in the New Jersey Coastal Plain. The quality of these sources of drinking water is a concern because they are vulnerable to contamination. Indications of the occurrence, distribution, and likely sources and transport mechanisms of certain contaminants were obtained from 48 selected reports and 2 selected data sets on water quality in or near the watersheds (1980-2001). These indications are described and briefly summarized in this report. The findings of studies on ground-water quality indicate that shallow ground water within the study area generally meets primary drinking-water standards, with notable exceptions. Volatile organic compounds, mercury, arsenic, radionuclides, nitrate, and coliform bacteria have been detected in shallow ground water in some areas at levels that exceed Federal and State drinking-water standards. For example, results of analyses of untreated samples collected from more than 13,000 private wells during 1983-99 indicated that concentrations of volatile organic compounds in samples from 7.3 percent of the wells exceeded at least 1 of 11 drinking-water standards, according to records maintained by the Ocean County Health Department. In cases of exceedances, however, water treatment, well replacement, and (or) retesting assured that applicable drinking-water standards were being met at the tap. Reported concentrations of the pesticide chlordane in some areas exceeded the drinking-water standard; few data are available on the occurrence of other pesticides. Studies of nearby areas, however, indicate that pesticide concentrations generally could be expected to be below drinking-water standards. The combination of low pH and low dissolved solids in many areas results in shallow ground water that is highly corrosive and, if untreated, able to

  2. Evaluation of the transfer and the accumulation of microcystins in tomato (Solanum lycopersicum cultivar MicroTom) tissues using a cyanobacterial extract containing microcystins and the radiolabeled microcystin-LR ({sup 14}C-MC-LR)

    Energy Technology Data Exchange (ETDEWEB)

    Corbel, Sylvain [INRA, UMR1402 ECOSYS, F-78850 Thiverval-Grignon (France); AgroParisTech, UMR1402 ECOSYS, F-78850 Thiverval-Grignon (France); Laboratoire Ecologie, Systématique et Evolution, UMR8079, Univ. Paris-Sud/CNRS/AgroParisTech, Université Paris-Sud, F-91405 Orsay (France); Mougin, Christian; Nélieu, Sylvie; Delarue, Ghislaine [INRA, UMR1402 ECOSYS, F-78850 Thiverval-Grignon (France); AgroParisTech, UMR1402 ECOSYS, F-78850 Thiverval-Grignon (France); Bouaïcha, Noureddine, E-mail: noureddine.bouaicha@u-psud.fr [Laboratoire Ecologie, Systématique et Evolution, UMR8079, Univ. Paris-Sud/CNRS/AgroParisTech, Université Paris-Sud, F-91405 Orsay (France)

    2016-01-15

    Microcystins are the most common cyanotoxins and may be expected wherever blooms of cyanobacteria occur in surface waters. Their persistence both in the irrigation water and in the soil can lead to their transfer and bioaccumulation into agricultural plants. The aim of this work was to investigate microcystin accumulation in Solanum lycopersicum cultivar MicroTom. The plant was exposed to either Microcystis aeruginosa crude extracts containing up to 100 μg eq. MC-LR L{sup −1} in a soil–plant system for 90 days or pure radiolabeled {sup 14}C-MC-LR in a hydroponic condition for 48 h. Toxin bioaccumulation in the soil and different plant tissues was assessed both by the PP2A inhibition assay and by liquid chromatography-mass spectrometry (LC/MS/MS). After 90 days of exposure, microcystins persisted in the soil and their free extractable concentrations accumulated were very low varying between 1.6 and 3.9 μg eq. MC-LR kg{sup −1} DW. Free MC-LR was detected only in roots and leaves with concentrations varying between 4.5 and 8.1 μg kg{sup −1} DW and between 0.29 and 0.55 μg kg{sup −1} DW, respectively. By using radioactivity ({sup 14}C-MC-LR), the results have reported a growing accumulation of toxins within the organs roots > leaves > stems and allowed them to confirm the absence of MC-LR in fruits after 48 h of exposure. The bioconcentration factor (BCF) was 13.6 in roots, 4.5 in leaves, and 1.4 in stems. On the other hand, the results highlight the presence of two radioactive fractions in different plant tissues. The non-extractable fraction of radioactivity, corresponding to the covalently bound MC-LR, was higher than that of the extractable fraction only in roots and leaves reaching 56% and 71% of the total accumulated toxin, respectively. Therefore, results raise that monitoring programs must monitor the presence of MCs in the irrigation water to avoid the transfer and accumulation of these toxins in crops. - Graphical abstract: Bioconcentration

  3. Análisis bibliométrico de los trabajos de grado del área organizacional de la Facultad de Psicología de la Universidad Santo Tomás

    Directory of Open Access Journals (Sweden)

    María Constanza Aguilar B.

    2007-01-01

    Full Text Available El propósito de esta investigación fue realizar un análisis bibliométrico de los trabajos de grado del área organizacional de la Facultad de Psicología de la Universidad Santo Tomás. Primero, se hizo una revisión todos los trabajos de grado de Psicología (1307 tesis de los cuales se seleccionaron 247 del área producidos durante 26 años, cerca del 19%, –período comprendido entre 1985-2005-. Luego, se diseñó una base de datos y de acuerdo con las variables previamente establecidas se sistematizaron los datos. El estudio fue de tipo descriptivo y se realizan dos tipos de análisis, uno de carácter descriptivo bibliométrico y el segundo, corresponde al análisis de datos textuales. Se encontró que de los 247 trabajos revisados se revelo que 1995 fue el año en el que se desarrollaron mayor número de tesis (50 trabajos; los enfoques teóricos de abordaje de las tesis son de: enfoque sistémico (51 trabajos seguidos por el enfoque cognitivo comportamental (26. Por último, se presento un valioso aporte metodológico, y es la inclusión del análisis de datos textual a la bibliometría, el cual revelo en primer lugar la relación entre la Psicología social y la Psicología organizacional; en segundo lugar se evidenciaron dos periodos donde las temáticas giran en torno a una visión clásica de la psicologia organizacional y en últimos 10 años un énfasis en una perspectiva critica de la psicologia de las organizaciones.

  4. A publicação de "A cabana do Pai Tomás" no Brasil escravista. O "momento europeu" da edição Rey e Belhatte (1853

    Directory of Open Access Journals (Sweden)

    Danilo José Zioni Ferretti

    Full Text Available Resumo Este artigo estuda o processo de publicação no Brasil escravista do principal romance antiescravista do séc. XIX: A Cabana do Pai Tomás , da escritora norte-americana Harriet Beecher Stowe. Apresentamos as condições e modalidades de publicação do romance vigentes no Brasil entre 1853 e 1888 e nos concentramos na análise da edição, em português, publicada em Paris pela casa Rey e Belhatte, em 1853. Articulando referenciais da história social dos escritos, da história do livro e dos estudos de transferências culturais, consideramos as intervenções realizadas pelo tradutor da obra, mediante a análise do material peritextual e os direcionamentos de sentido aí propostos. Analisamos esse processo de edição como um caso de transferência cultural triangular, com destaque para a importância das mediações europeias que marcam a difusão do livro da autora norte-americana no Brasil. Demonstramos, finalmente, como a edição estudada buscou atenuar as expectativas sociais originais do romance. Ao substituir o imediatismo do abolicionismo de Stowe por uma interpretação gradualista, a edição permitia, aos seus leitores, conceber o fim da escravidão num futuro bem mais longínquo, no mundo lusófono.

  5. Formas de evaluación educativa en la Universidad Santo Tomás, Sede Bogotá, Modalidad presencial. Analítica de unas relaciones de poder

    Directory of Open Access Journals (Sweden)

    Tomás Sánchez Amaya

    2012-01-01

    Full Text Available La indagación desarrollada por el Grupo Docimófilos en la segunda etapa de la investigación denominada “Caracterización de las formas evaluación educativa en la Universidad Santo Tomás Sede Bogotá, Modalidad Presencial. Etapa II: Perspectiva Genealógica”, versó sobre el análisis de las condiciones de posibilidad para la emergencia e instalación de las formas de evaluación educativa que fueron historiadas en la arqueología (primera etapa de la investigación. Así mismo, se realizó una analítica interpretativa acerca de las relaciones de poder que la malla evaluativa trama en el conjunto de las acciones que desarrolla la Universidad. El análisis muestra cómo la evaluación a través de una amplia red de dispositivos ha hecho presa de todas las instancias relativas y correlativas a la acción educativa; se ha filtrado e instalado en todos los órdenes y niveles de la educación; ha permeado la sociedad toda y en su seno, de modo extraordinario a las instituciones, en las cuales ha encontrado terreno fértil para su reproducción. Allí ha operado diversos procesos de gestión, se ha constituido en mecanismo de fabricación de saberes y ha tramado una diversidad de relaciones en las cuales el poder opera de múltiples formas; se ha convertido, en últimas, en una condición necesria, en parte natural y consustancial, de la educación.

  6. Search for evidence of trend slow-down in the long-term TOMS/SBUV total ozone data record: the importance of instrument drift uncertainty and fingerprint detection

    Directory of Open Access Journals (Sweden)

    R. S. Stolarski

    2006-05-01

    Full Text Available We have developed a merged ozone data (MOD data set for the period October 1978 through October 2005 combining total ozone measurements (version 8 retrieval from the TOMS (Nimbus 7, Meteor 3, and Earth Probe and SBUV/SBUV2 (Nimbus 7, NOAA 9/11/16 series of satellite instruments. We use MOD to search for evidence of ozone recovery in response to the observed leveling off of chlorine compounds in the stratosphere. A crucial step in any time series analysis is the evaluation of uncertainties. In addition to the standard statistical time-series uncertainties, we evaluate the possible instrumental drift uncertainty for the MOD data set. We combine these two sources of uncertainty and apply them to a cumulative sum of residuals (CUSUM analysis for trend slow-down. For the quasi-global mean between 60° S and 60° N, the apparent slow-down in trend is found to be clearly significant if instrument uncertainties are ignored. When instrument uncertainties are added, the slow-down becomes marginally significant at the 2σ level. For the mid-latitudes of the northern hemisphere (30° to 60° N the trend slow-down is significant. For the mid-latitudes of the southern hemisphere (30° to 60° S it is not significant. The fingerprint of ozone recovery expected from model calculations suggests both northern and southern mid-latitude total ozone levels should recover together. Our result fails this fingerprint test and is therefore not a demonstration of the response of total ozone to the leveling off of chlorine.

  7. La doctrina de Tomás de Aquino sobre la analogía como recurso para el conocimiento natural de dios. una meditación filosófica sobre sus límites y alcances

    Directory of Open Access Journals (Sweden)

    Lucero González Suárez

    2015-06-01

    Full Text Available El propósito de este ensayo consiste en reflexionar sobre el fundamento ontológico de la doctrina de Tomás de Aquino sobre analogía, con el fin de señalar sus alcances y límites para el conocimiento natural de Dios. En el primer apartado se reflexiona sobre la analogia entis. En el segundo, se define la analogía y sus tipos. En el tercero, se explica que a través de la analogía es posible acceder al conocimiento indirecto de Dios. En el cuarto, se plantea la pregunta acerca de cuál es el Dios al que permiten acceder las pruebas de la existencia de Dios basadas en la analogía, con el fin de argumentar que, como sostiene San Juan de la Cruz, entre las criaturas y Dios hay una infinita desemejanza, motivo por el cual, si bien es cierto que la analogía permite a la teodicea el conocimiento de Dios como causa, no es un medio proporcionado para el conocimiento de su ser sobrenatural. El artículo concluye con la exhibición de los límites del pensamiento analógico para el conocimiento esencial de Dios: de la trascendencia y el misterio que envuelven su presencia. La tesis a demostrar es que el conocimiento analógico de Dios es imperfecto e incompleto, pero no falso.

  8. 面向高光谱大气臭氧传感器的多观测几何条件下紫外辐射模拟及对TOMS V8算法臭氧初值估算模型改进与评价%Radiance Simulation of BUV Hyperspectral Sensor on Multi Angle Observation,and Improvement to Initial Total Ozone Estimating Model of TOMS V8 Total Ozone Algorithm

    Institute of Scientific and Technical Information of China (English)

    吕春光; 王维和; 杨文博; 田庆久; 卢山; 陈赟

    2015-01-01

    New hyperspectral sensor to detect total ozone is considered to be carried on geostationary orbit platform in the future , because local troposphere ozone pollution and diurnal variation of ozone receive more and more attention .Sensors carried on geo‐stationary satellites frequently obtain images on the condition of larger observation angles so that it has higher requirements of to‐tal ozone retrieval on these observation geometries .TOMS V8 algorithm is developing and widely used in low orbit ozone detec‐ting sensors ,but it still lack of accuracy on big observation geometry ,therefore ,how to improve the accuracy of total ozone re‐trieval is still an urgent problem that demands immediate solution .Using moderate resolution atmospheric transmission ,MODT‐RAN ,synthetic UV backscatter radiance in the spectra region from 305 to 360 nm is simulated ,which refers to clear sky ,multi angles (12 solar zenith angles and view zenith angles) and 26 standard profiles ,moreover ,the correlation and trends between at‐mospheric total ozone and backward scattering of the earth UV radiation are analyzed based on the result data .According to these result data ,a new modified initial total ozone estimation model in TOMS V8 algorithm is considered to be constructed in order to improve the initial total ozone estimating accuracy on big observation geometries .The analysis results about total ozone and simulated UV backscatter radiance shows :Radiance in 317.5 nm (R317.5 ) decreased as the total ozone rise .Under the small solar zenith Angle (SZA) and the same total ozone ,R317.5 decreased with the increase of view zenith Angle (VZA) but increased on the large SZA .Comparison of two fit models shows :without the condition that both SZA and VZA are large (>80°) ,expo‐nential fitting model and logarithm fitting model all show high fitting precision (R2 >0.90) ,and precision of the two decreased as the SZA and VZA rise .In most cases ,the precision of logarithm fitting

  9. Dr. Tom Frieden Reflects on 2014

    Centers for Disease Control (CDC) Podcasts

    2014-12-16

    There is no doubt Ebola will rank as the biggest public health story of 2014, but fighting Ebola is only one of the things CDC has done this year to protect the health of Americans.  Created: 12/16/2014 by Office of the Director, Office of the Associate Director for Communication (OADC).   Date Released: 12/16/2014.

  10. Tom Swift and His Electric Bilingual Grandmother

    Science.gov (United States)

    Manwell, Tom; And Others

    1973-01-01

    A description of a prototype computer assisted instruction system for teaching Russian. Although the course stresses the Russian morphological system, the construction of the computer program is applicable to other languages and language teaching specialties. (Author)

  11. A review of the Tom Rozwadowski medal

    African Journals Online (AJOL)

    OR field, he specialised in optimisation techniques, whilst also having a good knowledge ... ria decision analysis in water resource plan- ning. 1997 ..... TR 1985: An interactive decision support system was developed for South African Brew-.

  12. Die Geschichte von Tom Buk-Swienty

    DEFF Research Database (Denmark)

    Rønhede, Søren

    2010-01-01

    Buk-Swienty markedsfører sin seneste bog på en påstand om at have afsløret, at kongen, Christian IX, i 1864 gennem sin anmodning om optagelse i Det tyske Forbund søgte at nedlægge Danmark. Påstanden er uden hold i de historiske realiteter....

  13. Toxoplasma gondii infection: relationship between seroprevalence and risk factors among primary schoolchildren in the capital areas of Democratic Republic of São Tomé and Príncipe, West Africa

    Directory of Open Access Journals (Sweden)

    Fan Chia-Kwung

    2012-07-01

    Full Text Available Abstract Background The status of Toxoplasma gondii infection among primary schoolchildren (PSC of the Democratic Republic of São Tomé and Príncipe (DRSTP, West Africa, remains unknown to date. Methods A serologic survey and risk factors associated T. gondii infection among PSC in the DRSTP was assessed by the latex agglutination (LA test and a questionnaire interview including parents’ occupation, various uncomfortable symptoms, histories of eating raw or undercooked food, drinking unboiled water, and raising pets, was conducted in October 2010. Schoolchildren from 4 primary schools located in the capital areas were selected, in total 255 serum samples were obtained by venipuncture, of which 123 serum samples were obtained from boys (9.8 ± 1.4 yrs and 132 serum samples were obtained from girls (9.7 ± 1.3 yrs. Results The overall seroprevalence of T. gondii infection was 63.1% (161/255. No significant gender difference in seroprevalence was found between boys (62.6%, 77/123 and girls (63.6%, 84/132 (p = 0.9. The older age group of 10 years had insignificantly higher seroprevalence (69.9%, 58/83 than that of the younger age group of 8 year olds (67.7%, 21/31 (p = 0.8. It was noteworthy that the majority of seropositive PSC (75.8%, 122/161 had high LA titers of ≥1: 1024, indirectly indicating acute or repeated Toxoplasma infection. Parents whose jobs were non-skilled workers (73.1% showed significantly higher seroprevalence than that of semiskilled- (53.9% or skilled workers (48.8% (p p  Children who claimed to have had recent ocular manifestation or headache, i.e. within 1 month, seemed to have insignificantly higher seroprevalence than those who did not (p > 0.05. Conclusions Parents’ educational level and cats kept indoors seemed to be the high risk factors for PSC in acquisition of T. gondii infection. While, ocular manifestation and/or headache of PSC should be checked for the possibility of being

  14. Toxoplasma gondii infection: relationship between seroprevalence and risk factors among primary schoolchildren in the capital areas of Democratic Republic of São Tomé and Príncipe, West Africa.

    Science.gov (United States)

    Fan, Chia-Kwung; Lee, Lin-Wen; Liao, Chien-Wei; Huang, Ying-Chieh; Lee, Yueh-Lun; Chang, Yu-Tai; da Costa, Ângela dos Santos Ramos José; Gil, Vilfrido; Chi, Li-Hsing; Nara, Takeshi; Tsubouchi, Akiko; Akinwale, Olaoluwa Pheabian

    2012-07-13

    The status of Toxoplasma gondii infection among primary schoolchildren (PSC) of the Democratic Republic of São Tomé and Príncipe (DRSTP), West Africa, remains unknown to date. A serologic survey and risk factors associated T. gondii infection among PSC in the DRSTP was assessed by the latex agglutination (LA) test and a questionnaire interview including parents' occupation, various uncomfortable symptoms, histories of eating raw or undercooked food, drinking unboiled water, and raising pets, was conducted in October 2010. Schoolchildren from 4 primary schools located in the capital areas were selected, in total 255 serum samples were obtained by venipuncture, of which 123 serum samples were obtained from boys (9.8 ± 1.4 yrs) and 132 serum samples were obtained from girls (9.7 ± 1.3 yrs). The overall seroprevalence of T. gondii infection was 63.1% (161/255). No significant gender difference in seroprevalence was found between boys (62.6%, 77/123) and girls (63.6%, 84/132) (p = 0.9). The older age group of 10 years had insignificantly higher seroprevalence (69.9%, 58/83) than that of the younger age group of 8 year olds (67.7%, 21/31) (p = 0.8). It was noteworthy that the majority of seropositive PSC (75.8%, 122/161) had high LA titers of ≥1: 1024, indirectly indicating acute or repeated Toxoplasma infection. Parents whose jobs were non-skilled workers (73.1%) showed significantly higher seroprevalence than that of semiskilled- (53.9%) or skilled workers (48.8%) (p raising cats also showed significantly higher seroprevalence than those who did not (p 0.05). Parents' educational level and cats kept indoors seemed to be the high risk factors for PSC in acquisition of T. gondii infection. While, ocular manifestation and/or headache of PSC should be checked for the possibility of being T. gondii elicited. Measures such as improving environmental hygiene and intensive educational intervention to both PSC and their parents should be performed immediately so as to

  15. “Como Deus É Ciente em sua Essência Divina”: a Presciência de Deus em Santo Tomás de Aquino e no Livro da Contemplação (C. 1271-1273 de Ramon Llull

    Directory of Open Access Journals (Sweden)

    Ricardo da Costa

    2015-08-01

    Full Text Available A proposta deste trabalho é analisar a concepção filosófica depresciência em Santo Tomás de Aquino e Ramon Llull, nas obrasSuma Teológicae O Livro da Contemplação. Para isso, discorremos previamente sobre o conceito deciência, base aristotélica tomista. Por fim, apresentamos a tradução (inédita de um extrato doLivro da Contemplação, como base documental para a segunda parte do trabalho.

  16. Aspectos econômicos da produção e do risco nos sistemas agroflorestais e nos sistemas tradicionais de produçâo agrícola em tomé-açu, Pará - 2001 a 2003 Economic aspects of production under risk conditions in agroforestry systems and traditional agricultural systems in tomé-açu, Pará - 2001 to 2003

    Directory of Open Access Journals (Sweden)

    Luiz Benedito Varela

    2009-02-01

    Full Text Available Neste artigo, analisaram-se os fatores determinantes da produção dinâmica dos sistemas agroflorestais (SAF e dos sistemas tradicionais de produção agrícola (ST, sob condições de risco, em pequenas e médias unidades produtivas nipo-brasileiras localizadas no Município de Tomé-Açu, Pará, no período de 2001 a 2003. Os resultados indicaram que todos os fatores, exceto a mão-de-obra contratada e as máquinas e equipamentos, afetam diretamente o Valor Bruto da Produção (VBP dos SAF e dos ST; a variável dummy apresentou diferença cumulativa a menor no VBP dos SAF, de um ano para outro. A função de risco estimada apontou que os SAF apresentaram menor risco que os ST, evidenciando-se que a aplicação de insumos era fonte de redução de risco, mas a tecnologia adotada precisa ser adequada, pois se apresenta como fator de aumento de risco nos dois sistemas. Além disso, a dummy indicou que os SAF exibiram menor nível de risco que os ST. Nesse contexto, os resultados deixaram claro, ainda, que os produtores nipo-brasileiros eram avessos ao risco.This article analyzes the determinants of the dynamic production inputs of the agroforestry systems (SAF and traditional agricultural systems (ST under risk conditions, in small and medium farms in Tome-Açu, Pará, by Brazilian-Japanese producers from 2001 to 2003. The dynamic regression model results showed that all the inputs, except labor and machinery, have positive impacts on the current VBP of the two systems analyzed. Furthermore, the dummy variable shows a minor accumulative difference of the SAF's VBP in comparison with ST's VBP, from one period (year to another. The estimated risk function indicates that the use of fertilizer and pesticides reduce the risk level of the two systems, but the current technology needs to be adequate to other production inputs, since it appears as a factor of increased risk to the two systems. In addition, the dummy variable indicates that the SAF

  17. Open system sulphate reduction in a diagenetic environment - Isotopic analysis of barite (δ34S and δ18O) and pyrite (δ34S) from the Tom and Jason Late Devonian Zn-Pb-Ba deposits, Selwyn Basin, Canada

    Science.gov (United States)

    Magnall, J. M.; Gleeson, S. A.; Stern, R. A.; Newton, R. J.; Poulton, S. W.; Paradis, S.

    2016-05-01

    Highly positive δ34S values in sulphide minerals are a common feature of shale hosted massive sulphide deposits (SHMS). Often this is attributed to near quantitative consumption of seawater sulphate, and for Paleozoic strata of the Selwyn Basin (Canada), this is thought to occur during bacterial sulphate reduction (BSR) in a restricted, euxinic water column. In this study, we focus on drill-core samples of sulphide and barite mineralisation from two Late Devonian SHMS deposits (Tom and Jason, Macmillan Pass, Selwyn Basin), to evaluate this euxinic basin model. The paragenetic relationship between barite, pyrite and hydrothermal base metal sulphides has been determined using transmitted and reflected light microscopy, and backscatter electron imaging. This petrographic framework provides the context for in-situ isotopic microanalysis (secondary ion mass spectrometry; SIMS) of barite and pyrite. These data are supplemented by analyses of δ34S values for bulk rock pyrite (n = 37) from drill-core samples of un-mineralised (barren), siliceous mudstone, to provide a means by which to evaluate the mass balance of sulphur in the host rock. Three generations of barite have been identified, all of which pre-date hydrothermal input. Isotopically, the three generations of barite have overlapping distributions of δ34S and δ18O values (+22.5‰ to +33.0‰ and +16.4‰ to +18.3‰, respectively) and are consistent with an origin from modified Late Devonian seawater. Radiolarian tests, enriched in barium, are abundant within the siliceous mudstones, providing evidence that primary barium enrichment was associated with biologic activity. We therefore propose that barite formed following remobilisation of productivity-derived barium within the sediment, and precipitated within diagenetic pore fluids close to the sediment water interface. Two generations of pyrite are texturally associated with barite: framboidal pyrite (py-I), which has negative δ34S values (-23‰ to -28

  18. Contribuição para o conhecimento da biologia de Cynosciou jamaicensis (Vaillant & Bocourt, 1883, na area entre cabo de São Tomé (22º04's e Torres (29º21's, Brasil A contribution to the biology acquirement of Cynoscion jamaicebis (Vaillant & Bocourt, 1883, in the area between Cabo de São Tomé (22º01'S and Torres (29º21'S, Brazil

    Directory of Open Access Journals (Sweden)

    Anna Emília A. de M Vazzoler

    1983-01-01

    Full Text Available Este trabalho baseia-se na análise de dados obtidos de 1891 exemplares de Cynoscion jamaicebis coletados durante quatro cruzeiros oceanográficos realizados por intermédio do N/Oc. "Prof. W. Besnard", na área entre Cabo de Sao Tomé (22º04'S e Torres (29º30'S, até a isóbata de 200 m, dentro do programa FAUNEC. A espécie distribui-se ao longo da plataforma continental, preferencialmente na região banhada pela agua costeira, com temperaturas entre 27ºC e 18ºC. Ocorrem concentrações de jovens e adultos, indiscriminadamente da distância da costa; os jovens ocorreram, em fevereiro-março, entre 22ºS e 27ºS e, nos demais períodos, entre 23º20'S e 27º30'S, enquanto os adultos distribulram-se, em fevereiro-março e maio, entre 26ºS e 27º30'S e, em setembro e novembro, entre 23ºS e 29º30'S. A desova ocorre entre as latitudes 24º30'S e 26º30'S, durante o fim do inverno-primavera (setembro-novembro. Concordando com o ciclo reprodutivo, o fator de condição mostrou variações cíclicas, com valor mais baixo durante setembro, período de desova. O pico de recrutamento verificou-se em maio, quando ocorreram indivíduos com comprimento total entre 70 e 90 mm, provenientes da desova do ano anterior, que ainda nao completaram um ano de idade. 0 comprimento médio de início da primeira maturação sexual é de 154 mm, sendo que aos 200 mm todos os indivíduos estão aptos para a reprodução. A relação peso total/comprimento total apresentou diferenças estatisticamente significativas entre sexos, com α = 3,25 para machos e 3,10 para fêmeas.Data were obtained from 1891 specimens of Cynoscion jamaicebis collected during four trips aboard R/V "Prof. W. Besnard'', from Cabo de São Tome (22º04'S to Torres (29º21'S. This species occurs along the continental shelf, preferably on the region of coastal water influence with temperatures between 27ºC and 18ºC. There are young and adults along the coast, in all depths, although it was

  19. Elaboración y Utilización del aula virtual educativa en la asignatura de Matemática para desarrollar la Inteligencia Lógica- Matemática de los estudiantes de Noveno Básico "C" y "D" de la Unidad Educativa Salesiana "Santo Tomás Apostol", provincia de Chimborazo, cantón Riobamba durante el período Académico 2013-2014

    OpenAIRE

    Ávila Pesántes, Janeth Patricia

    2015-01-01

    This investigation is a comparative study between using and not using the virtual classroom for the development of the logic - mathematical in ninth grade students parallel "C" and “D” of " Unidad Educativa Santo Tomás Apóstol " and shows how virtual classroom helps to potentiate the logical thinking - applying mathematical support, exercises, games and additional activities presented in the virtual classroom. We worked in two groups: freshmen parallel Basic Education "C" belong to the quasi ...

  20. Buwalda: "TomTom voor potplantentelers die energiezuiniger willen telen" (interview met Fokke Buwalda)

    NARCIS (Netherlands)

    Arkesteijn, M.; Buwalda, F.

    2008-01-01

    In het project 'Energiezuinige teeltplannen voor de potplantenteelt' is een eerste stap gezet door telers te intervieuwen. De onderzoekers weten nu wat telers op het gebied van energie belangrijk vinden en aan wat voor soort modellen ze behoefte hebben. Op basis van deze wensen werkt een team van on

  1. « Pues Vuestra Magestad fue serbido de me haçer de Su Consejo » : modalités et écritures de l’itinérance dans la correspondance de Fray Tomás de Berlanga (c. 1490-1551)

    OpenAIRE

    Berens, Loann

    2017-01-01

    L’article aborde la figure de Fray Tomás de Berlanga (c. 1490-1551) à la fois comme homme d’Église et comme homme du roi. Pris dans cette double dimension et non plus seulement comme découvreur des îles Galápagos, le dominicain apparaît comme un homme de mouvement au service de la Monarchie catholique. L’étude de son parcours, de Saint-Domingue à Panamá en passant par la Nouvelle Espagne et le Pérou, et de sa correspondance en partie inédite dévoilent alors diverses modalités du déplacement e...

  2. Gestão estratégica na produção e comercialização do cacau em São Tomé e Principe /África: diferenciação a partir do cacau orgânico

    OpenAIRE

    Ramos Pires, Célia Eleyde; Moraes Filho, Rodolfo Araujo

    2014-01-01

    A presente pesquisa objetivou analisar os fatores que caracterizaram a mudança de ênfase da produção do cacau tradicional para o cacau orgânico em São Tomé e Principe na África e sua repercussão na organização de pequenos produtores. A pesquisa de natureza qualitativa e descritiva quando ao método de interpretação dos dados, teve como procedimento para a observação do fenômeno em foco, o estudo de casos múltiplos. O referencial teórico retratou o conceito de gestão estratégica, ambiente conco...

  3. Intenção educacional da ética de Tomás de Aquino no contexto citadino no século XIII The educational intention in the ethics of Thomas Aquinas, and its urban context, in the thirteenth century

    Directory of Open Access Journals (Sweden)

    Tatyana Murer Cavalcante

    2012-06-01

    Full Text Available O objetivo deste texto é tecer considerações sobre a concepção de ética de Tomás de Aquino (1224-5?/1274, a partir da relação entre produção do conhecimento e transformações sociais. Selecionamos para análise a questão "As consequências dos atos humanos em razão da bondade e da malícia", oriunda da obra principal do autor, a Suma de Teologia. Faremos este debate à luz de estudiosos da contemporaneidade que tratam do tema, com destaque especial para Le Goff, Lauand e Oliveira. Compreendemos que a elaboração de Tomás de Aquino, gestada na e para a cidade, afirmava a necessidade do conhecimento e do ensino de virtudes orientadas para as relações sociais que implicavam a responsabilidade pessoal. Consideramos que este estudo pode nos apontar caminhos para o debate sobre a ética na atualidade.The goal here is to consider the ethical conception reasoned out by Thomas Aquinas (12245?/1274, beginning with the relationship between knowledge production and social transformation. We selected, for analysis, the topic: "The consequences of human actions on grounds of goodness and malice" from the author's main work, the Summa of Theology. We will stage this debate in the light of contemporary scholars dealing with the issue, paying attention, in particular, to Le Goff, Lauand and Oliveira. It is our understanding that the ideas developed by Thomas Aquinas conceived of, both in and for the city, confirmed the need for knowledge of, and teaching of, virtues; such virtues being oriented towards social relationships that have personal responsibility implicit in them. We consider that this study may point the way to a debate about ethics suited to the present day.

  4. Archetypal Criticism of the Eternal Wanderer--Based on the Adventures of HuckleberryFinn and the Adventures of Tom Sawyer%神话原型批评之永恒的流浪--《以哈克贝利·芬恩历险记》与《汤姆·索亚历险记》为例

    Institute of Scientific and Technical Information of China (English)

    田莹莹

    2014-01-01

    The adventures of HuckleberryFinn and the adventures of Tom Sawyer are the masterpieces of Mark Twain's literary works that closely relating to the life of children. This essay is based on the behaviors and characters of the heroes and further concludes that both Huck and Tom were born in poor families, being naughty, upright, brave and adventurous. By analyzing another three novels---Waiting for Godot, The Collar and The Insulted and Humiliated, the archetype of tramps are finally revealed via the theory of archetypal criticism in the essay, which intends to offer some hints for the explanation of the two novels.%《哈克贝利·芬恩历险记》与《汤姆·索亚历险记》是马克·吐温儿童文学的代表作,文章从哈克与汤姆的表现和性格特征出发,分析了流浪汉身上的共性,即身世可怜、淘气、正直、勇敢、热衷冒险。在此基础上,结合《等待戈多》、《衬衫领子》、《被欺凌的与被侮辱的》三部小说,运用神话原型批评理论,探究了流浪汉原型在小说中的具体体现,以期对这两部作品方面的解读有一定的启示。

  5. 一出没有女巫的女巫戏——解读凯丽尔·丘吉尔的社会主义女性主义名剧《醋汤姆》%A Witch Ray without a Witch: Carol Churchill's Vinegar Tom

    Institute of Scientific and Technical Information of China (English)

    秦文

    2009-01-01

    历史剧(Vinegar Tom)是英国女剧作家凯丽尔·丘吉尔(Caryl Churchill)对英国17世纪猎捕和焚烧女巫历史事件的一个社会主义女性主义的反思.通过生产、性和生育这三重视角,丘吉尔向读者展示了女性在资本主义和男权社会下受到的经济和意识形态的双重压迫,重塑了被指控为女巫的女性主体的真实形象.这出"没有女巫的女巫剧"揭示了历史上所谓"女巫"的真正"罪恶"不是邪恶,而是对女性在资本主义私有制经济下贫穷、残酷的生存现实的挑战以及对男权理念的反抗.

  6. A lei natural de tomás de aquino como princípio da razão prática e a segunda escolástica = The natural law of thomas aquinas as the principle of practical reason and second scholastic

    Directory of Open Access Journals (Sweden)

    Honnefelder, Ludger

    2010-01-01

    Full Text Available A teoria da lei natural sofre uma transformação na Segunda Escolástica (séculos 16-17, que pode ser entendida como uma resposta a uma experiência de crise. Aqui, não se trata só de uma comparação entre a visão de mundo cristã e a ética aristotélica, mas está em jogo a relação entre essa síntese e as tradições dos novos povos descobertos, dando impulso ao debate acerca de uma base moral obrigatória a ser encontrada na própria natureza e com validade universal. No intuito de explicar essas questões, os autores dos séculos 16 e 17 se voltaram grandemente a Tomás de Aquino. Mas, a abordagem da lei natural, por Scotus, também desempenha um papel significativo nesse contexto. A sua teoria da lei natural, com uma ênfase particular no papel da vontade e da autoridade divinas para tornar manifesto o conteúdo (como tal racional da lei natural lato sensu e com um acento no conceito de “consonância”, deve ser destacada para que se ganhe clareza sobre novos aspectos da teoria da lei natural na Segunda Escolástica

  7. Industrial Investment V.S. Financial Investment——Dialogue between Mr. Wang Yanmou & Tom Clough%实业资本与金融资本利弊分析——王燕谋与汤姆·克拉夫对话水泥投资

    Institute of Scientific and Technical Information of China (English)

    2007-01-01

    3月29日,应瑞士豪西盟(Holcim)公司的请求,在中国水泥协会副秘书长庄春来的安排下,Holcim全球执委会成员,负责北亚、南非及中国、澳大利亚等国家业务的汤姆.克拉夫先生(Tom Clough)及其助手-亚太地区执委会成员丹尼尔·巴赫先生、集团驻华首席代表莫魁先生等一行人就Holcim与华新水泥公司的合作问题在北京专程拜访了原国家建材局局长、本刊高级顾问王燕谋同志,双方进行了愉快而坦诚的会谈。《中国水泥》杂志总编辑张建新陪同参加了会见。

  8. Nas franjas do império ultramarino português: a experiência insular de São Tomé e Príncipe no despertar dos oitocentos In the far-flung corners of the Portuguese overseas Empire: the island experience of Sao Tome and Principe at the beginning of the 19th century

    Directory of Open Access Journals (Sweden)

    Neuma Brilhante

    2009-01-01

    Full Text Available São Tomé e Príncipe ocupou importante lugar na arquitetura imperial no século XVI. Contudo, a capitania tornou-se cada vez mais periférica no contexto do império português em decorrência de sérios problemas internos e dos deslocamentos do comércio colonial. As iniciativas reformistas experimentadas no início dos oitocentos fracassaram diante das importantes mudanças político-econômicas que envolveram o tráfico atlântico, principalmente, das ações inglesas contra esse comércio.Sao Tome and Principe held an important position within the Portuguese Empire in the 16th century. However due to serious internal conflicts and the transfer of priorities in colonial trade, this colonial island was gradually relegated. At the onset of the 19th century, a new administrative reform failed to restore their former affluence because of the consequences of important politico-economic changes concerning transatlantic trade, mainly, the British intervention against this trading.

  9. TOM - Manufacture and modelling of a demonstration oxide module; TOM, Erstellen und Modellierung eines thermo-elektrischen oxidischen Moduls (TOM) als Demonstrator - Jahresbericht 2007

    Energy Technology Data Exchange (ETDEWEB)

    Tomes, P.; Weidenkaff, A.

    2007-07-01

    This annual report for the Swiss Federal Office of Energy (SFOE) takes a look at the work done at the Swiss Federal Laboratories for Materials Science and Technology EMPA in 2007 on demonstrating the thermoelectric effects of an oxide module. Four-leg oxide-based thermoelectric modules are described which have been produced by combining p and n-type oxide elements. The modules were assembled using a mixture of silver paste along with silver and copper oxide powders. Three types of thermoelectric oxide modules with different thermocouple leg-lengths were examined. In this type of module, p and n-type semiconductor thermocouples are connected electrically in series by highly conducting metal strips using silver with copper oxide and sandwiched between thermally conducting but electrically insulating plates made of corundum. The results obtained are presented in graphical form and discussed.

  10. Extraction and anticoagulant activity of sulfated polysaccharides from Caulerpa cupressoides var. lycopodium (Vahl C. Agardh (Chlorophyceae = Extração e atividade anticoagulante dos polissacarídeos sulfatados da clorofícea Caulerpa cupressoides var. lycopodium (Vahl C. Agardh = Extração e atividade anticoagulante dos polissacarídeos sulfatados da clorofícea Caulerpa cupressoides var. lycopodium (Vahl C. Agardh.

    Directory of Open Access Journals (Sweden)

    José Ariévilo Gurgel Rodrigues

    2011-04-01

    Full Text Available The reportedly low standard quality of heparin (HEP for use in cardiac surgeries has led to concern in the Brazilian and international markets. Sulfated polysaccharides (SPs from seaweeds have been regarded as promising substitutes for HEP. The aim of this study was to sequentially extract total SPs (TSPs from Caulerpa cupressoides (Chlorophyceae with papain in 100 mM sodium acetate buffer (pH 5.0 containing 5 mM cysteine and 5 mM EDTA, followed byfractionation by ion-exchange chromatography (DEAE-cellulose, and then evaluate the anticoagulant potential of SP fractions by activated partial thromboplastin time (APTT using normal human plasma and compare it to standard HEP (193 IU mg-1. The obtained fractions were chemically characterized by chemical composition and agarose gel electrophoresis. The yield was 4.61%, and three fractions of SP (F I, F II and F III eluted with 0.50, 0.75 and 1.00 M of NaCl,respectively, were observed on chromatography profiles; however, differences in charge densities patterns and degree of resolution among them were revealed by electrophoresis. SPs were capable of modifying APTT only in fractions eluted with 0.75 M of NaCl, whose activities were 23.37 and 25.76 IU mg-1, respectively, and the charge density was prerequisite to activity. Therefore, C. cupressoides is a source of SPs possessing low anticoagulant potential compared to HEP.O baixo padrão de qualidade outrora declarado da heparina (HEP para o uso em cirurgias cardíacas tem levado preocupação nos mercados nacional e internacional. Os polissacarídeos sulfatados (PSs de algasmarinhas têm sido considerados como promissores substitutos para HEP. Objetivou-se a extrair sequencialmente PSs totais (PSTs da clorofícea Caulerpa cupressoides com papaína em tampão acetato de sódio 100 mM (pH 5,0 contendo cisteína 5 mM e EDTA 5 mM, fracionar por cromatografia de troca iônica (DEAE-celulose e avaliar o potencial anticoagulante das frações de PS por meio do tempo de tromboplastina parcial ativada (TTPA, utilizando plasma humano normal e comparando-se à HEP padrão (193 IU mg-1. As frações obtidas foram caracterizadas quimicamente em composição química e por eletroforese em gel de agarose. O rendimento de PSTs foi 4,61% e os perfis cromatográficos, em DEAE-celulose, indicaram a separação de três frações de PS (F I; F II e F III eluídas nas concentrações 0,50; 0,75 e 1,00 M de NaCl, respectivamente, revelando, por eletroforese, diferenças em termos de densidade de cargas e graude resolução. Os PSs foram capazes de modificar o TTPA somente nas frações eluídas com 0,75 M de NaCl, cujas atividades foram 23,37 e 25,76 IU mg-1, respectivamente, quando a densidade de cargas foi pré-requisito para atividade. Portanto, C. cupressoides é uma fonte de PSs com baixos potenciais anticoagulantes comparados à HEP.

  11. Comparación en calidad de vida y estado nutricional entre alumnos de nutrición y dietética y de otras carreras universitarias de la Universidad Santo Tomás de Chile Comparison between the quality of life and nutritional status of nutrition students and those of other university careers at the Santo Thomas University in Chile

    Directory of Open Access Journals (Sweden)

    S. Durán Agüero

    2012-06-01

    Full Text Available Objetivo: Determinar y comparar la calidad de vida, estado nutricional y auto percepción de imagen corporal entre estudiantes de Nutrición y Dietética (ND con otras carreras (OC de la Universidad Santo Tomas (UST, Sede Viña del Mar. Métodos: Se evaluaron 200 estudiantes voluntarios (100 ND y 100 OC aplicándoles: una encuesta de calidad de vida, evaluación nutricional y encuesta de autopercepción de imagen corporal. Resultados: El grupo ND presentó menor percepción de su calidad de vida, consumo de tabaco y sedentarismo. Mujeres ND presentaron menor IMC y circunferencia de cintura (CC y hombres ND presentaron menor CC (p Objective: To determine and compare the quality of life, nutritional status, and self-perceived body image between nutrition students and students from other careers from the University Santo Tomás-Viña del Mar. Methods: We evaluated 200 student volunteers (100 nutrition students and 100 students from other careers with a quality of life survey, a nutritional evaluation, and a survey of body image perception. Results: The group of nutritional students perceived a lower quality of life, consumed less tobacco, and was less sedentary. Women of the nutritional group had a lower BMI and showed a lower hip circumference. Men of the nutritional group also showed a lower hip circumference. The nutritional group consumed more milk, chicken, and fish in their diet. Both groups presented an elevated consumption of alcohol. The concordance between BMI and body image was low, 34% in the nutritional group and 38% in the other careers group (Kappa 0.04 and 0.02. Conclusion: With respect to perception of quality of life, students from other careers perceived a better quality of life, however students from the nutritional group presented better nutritional status and selection of food.

  12. 83-aastane filmimagnaat vallandas Tom Cruise'i / Mikk Salu

    Index Scriptorium Estoniae

    Salu, Mikk, 1975-

    2006-01-01

    Paramount Pictures'i suuromanik Sumner Redstone süüdistab filmistaari "Võimatu missiooni" 3. filmi turunduskampaaniale kahjutekitamises, algatades sellega staaride ja stuudiobosside vahelise sõnasõja

  13. Tom Farley's Three Secrets for Prize Winning School Lunches.

    Science.gov (United States)

    Farmer, Jean

    1978-01-01

    The food director of the Milwaukee Public Schools offers his advice: discover what kids want, and then give it to them; snack bars and vendors must not compete with school lunches; and you must have professionals running the food service. (Author/MLF)

  14. Tom Pickering as a clinical scientist: masked hypertension.

    Science.gov (United States)

    Eguchi, Kazuo

    2010-04-01

    Masked hypertension has been 'unmasked' by the use of the out-of-office measurement of blood pressure, as home BP monitoring or ambulatory blood pressure monitoring has become available. The term masked hypertension could be used more widely than the original version of masked hypertension; morning hypertension, stress-induced hypertension, and nocturnal hypertension are all classified as subtypes of masked hypertension. Masked hypertension can also be seen in patients with diabetes, that could change clinical practice in diabetes. Masked hypertension is associated with cardiovascular events, but most of the outcome studies are on antihypertensive medications. Therefore, masked hypertension includes insufficient treatment of hypertension. In Dr Pickering's latest review of masked hypertension, prehypertension or high normal blood pressure was stressed as an associating factor with masked hypertension. The biggest theme in the field of hypertension is how we can detect masked hypertension. I present two interesting cases of possible masked hypertension in this commentary.

  15. Privaatne - Läti kaasaegne fotokunst / Toms Ķencis

    Index Scriptorium Estoniae

    Ķencis, Toms

    2010-01-01

    Läti fotograafia näitus "Private: Contemporary Photo Art in Latvia" Riias 20. augustist 18. oktoobrini 2009, kuraator Alise Tifentāle. Lähemalt Arnis Balčus'i, Gunārs Binde, Zenta Dzividzinskat'i, Roman Korovini, Inta Ruka, Alnis Stakle, Vilnis Vītoliņš'i loomingust

  16. Schaulust und Horror Soziokulturelle - Perspektiven auf PEEPING TOM

    Directory of Open Access Journals (Sweden)

    Thomas Ballhausen

    2010-09-01

    Full Text Available Die Geschichte des Kinos und des Films ist mindestens ebenso sehr eine Geschichte des Schreckens (und der damit verbundenen Schaulust wie sie eine Geschichte des Dokumentarischen zu sein scheint. Es sind die außergewöhnlichen Körper und deren Bewegungen, die das Publikum zu allen Zeiten faszinierten, schockierten und zum Schauen und Sehen lockten. Besonders das Genre des Horrorfilms ist mit diesem zentralen Aspekt des Kinos besonders deutlich verbunden.

  17. Talking about the Girl Who Loved Tom Gordon

    Science.gov (United States)

    Jones, Christie

    2005-01-01

    A high school teacher has used a novel by Stephen King as her end-of-the-year literature unit to teach her students. She suggests how this selection helps in achieving her goals to get students to practice reading and discussing literature and to apply these skills beyond the English classroom.

  18. 'Tom & Viv' ehk Elulugu kunstiks / Jaak Rähesoo

    Index Scriptorium Estoniae

    Rähesoo, Jaak, 1941-

    1996-01-01

    Mängufilm Thomas Stearns Eliotist Michael Hastingsi näidendi põhjal, stsenaristid Michael Hastings ja Adrian Hodges, re̓issöör Brian Gilbert : Suurbritannia, 1994. Ka autori suhtumisest Madis Kõivu ja Jaan Krossi biograafilistesse teostesse. Järg: 26. jaan., lk. 12

  19. Supplementary heat requirements when brooding tom turkey poults

    African Journals Online (AJOL)

    EXPER

    1 Ministry of Agricultural & Rural Affairs, Provincial Agricultural Directory, ..... and structural elements (Qe) (window (Qw), door (Qd), wall (Qw) and curtain (Qc)) ..... in animal genetics, nutrition, housing equipment and management schemes.

  20. Tarneahela juhtimine annab konkurentsieelise / Tom Vollmann, Carlos Cordon, Hakon Raabe

    Index Scriptorium Estoniae

    Vollmann, Tom

    2003-01-01

    Autorid selgitavad tarneahela juhtimise mõistet, kirjeldavad tarneahela kaardistamise ja juhtimise metoodika rakendamise võimalusi äritegevuses kulude vähendamiseks, väärtuse suurendamiseks ning jaotusahela konkurentsivõime tõstmiseks

  1. Tarneahela juhtimine annab konkurentsieelise / Tom Vollmann, Carlos Cordon, Hakon Raabe

    Index Scriptorium Estoniae

    Vollmann, Tom

    2003-01-01

    Autorid selgitavad tarneahela juhtimise mõistet, kirjeldavad tarneahela kaardistamise ja juhtimise metoodika rakendamise võimalusi äritegevuses kulude vähendamiseks, väärtuse suurendamiseks ning jaotusahela konkurentsivõime tõstmiseks

  2. 'Tom & Viv' ehk Elulugu kunstiks / Jaak Rähesoo

    Index Scriptorium Estoniae

    Rähesoo, Jaak, 1941-

    1996-01-01

    Mängufilm Thomas Stearns Eliotist Michael Hastingsi näidendi põhjal, stsenaristid Michael Hastings ja Adrian Hodges, re̓issöör Brian Gilbert : Suurbritannia, 1994. Ka autori suhtumisest Madis Kõivu ja Jaan Krossi biograafilistesse teostesse. Järg: 26. jaan., lk. 12

  3. Tom Friedman on Education in the "Flat World"

    Science.gov (United States)

    School Administrator, 2008

    2008-01-01

    In his best-selling book, "The World Is Flat," Thomas Friedman describes that the real world is becoming "flat." He describes how 10 forces are "flattening" the 21st century--making it easier for people in India, China and around the world to compete with Americans and others who had triumphed the century before. This article presents an interview…

  4. Ground control to major TOM: mitochondria-nucleus communication.

    Science.gov (United States)

    Eisenberg-Bord, Michal; Schuldiner, Maya

    2017-01-01

    Mitochondria have crucial functions in the cell, including ATP generation, iron-sulfur cluster biogenesis, nucleotide biosynthesis, and amino acid metabolism. All of these functions require tight regulation on mitochondrial activity and homeostasis. As mitochondria biogenesis is controlled by the nucleus and almost all mitochondrial proteins are encoded by nuclear genes, a tight communication network between mitochondria and the nucleus has evolved, which includes signaling cascades, proteins which are dual-localized to the two compartments, and sensing of mitochondrial products by nuclear proteins. All of these enable a crosstalk between mitochondria and the nucleus that allows the 'ground control' to get information on mitochondria's status. Such information facilitates the creation of a cellular balance of mitochondrial status with energetic needs. This communication also allows a transcriptional response in case mitochondrial function is impaired aimed to restore mitochondrial homeostasis. As mitochondrial dysfunction is related to a growing number of genetic diseases as well as neurodegenerative conditions and aging, elucidating the mechanisms governing the mitochondrial/nuclear communication should progress a better understanding of mitochondrial dysfunctions. © 2016 Federation of European Biochemical Societies.

  5. Tom ja Anni said suureks / Kairit Tsäro

    Index Scriptorium Estoniae

    Tsäro, Kairit, 1974-

    2011-01-01

    ETV staažikas lastesaade "Saame kokku Tomi juures" lõpetab. Saate produtsent Margus Saar, Anni - Maria Soomets ja postiljon Eedi - Kalju Orro, vaatavad tagasi viiele aastale ja meenutavad saatekülalisi

  6. Overflødige ord, tom jargon og forkludrede udtryk

    DEFF Research Database (Denmark)

    Kock, Christian Erik J

    2014-01-01

    Professor i retorik Christian Kock kaster et blik på Højberg Rapporten, der indeholder 23 anbefalinger til bedre kommunikation på Københavns Universitet. Han mener ikke, at rapporten selv kan tjene som eksempel på vellykket kommunikation....

  7. Tom test 8/26/02 11:45am

    Science.gov (United States)

    2000-01-01

    Members of the flight and ground crews prepare to unload equipment from NASA's B377SGT Super Guppy Turbine cargo aircraft on the ramp at NASA's Dryden Flight Research Center at Edwards Air Force Base, Calif. The outsize cargo plane had delivered the latest version of the X-38 flight test vehicle to NASA Dryden when this photo was taken on June 11, 2000. The B-377SGT Super Guppy Turbine evolved from the 1960s-vintage Pregnant Guppy, Mini Guppy and Super Guppy, used for transporting sections of the Saturn rocket used for the Apollo program moon launches and other outsized cargo. The various Guppies were modified from 1940's and 50's-vintage Boeing Model 377 and C-97 Stratocruiser airframes by Aero Spacelines, Inc., which operated the aircraft for NASA. NASA's Flight Research Center assisted in certification testing of the first Pregnant Guppy in 1962. One of the turboprop-powered Super Guppies, built up from a YC-97J airframe, last appeared at Dryden in May, 1976 when it was used to transport the HL-10 and X-24B lifting bodies from Dryden to the Air Force Museum at Wright-Patterson Air Force Base, Ohio. NASA's present Super Guppy Turbine, the fourth and last example of the final version, first flew in its outsized form in 1980. It and its three sister ships were built in the 1970s for Europe's Airbus Industrie to ferry outsized structures for Airbus jetliners to the final assembly plant in Toulouse, France. It later was acquired by the European Space Agency, and then acquired by NASA in late 1997 for transport of large structures for the International Space Station to the launch site. It replaced the earlier-model Super Guppy, which has been retired and is used for spare parts. NASA's Super Guppy Turbine carries NASA registration number N941NA, and is based at Ellington Field near the Johnson Space Center. For more information on NASA's Super Guppy Turbine, log onto the Johnson Space Center Super Guppy web page at http://spaceflight.nasa.gov/station/assembly/superguppy/

  8. DIGITAL FLOOD INSURANCE RATE MAP DATABASE, TOM GREEN COUNTY, TEXAS

    Data.gov (United States)

    Federal Emergency Management Agency, Department of Homeland Security — The Digital Flood Insurance Rate Map (DFIRM) Database depicts flood risk information and supporting data used to develop the risk data. The primary risk...

  9. Every Tom,Dick and Harry的含义

    Institute of Scientific and Technical Information of China (English)

    霍秀梅

    2013-01-01

    一大早,同事就来抱怨:“我本想办一个小型的私人聚会,没想到老婆把该请的、不该请的全请来了!”如何用英语来表达“该请的和不该请的”?看好了:“Every Tom,Dick and Harry”。这里的“Tom,Dick and Harry”,泛指普通人,但含有蔑视意,特指“非常非常一般、毫无半点建树的普通人”,如:Every Tom,Dick and Harry is qualified to do the job.(这活儿谁都能干!)

  10. Privaatne - Läti kaasaegne fotokunst / Toms Ķencis

    Index Scriptorium Estoniae

    Ķencis, Toms

    2010-01-01

    Läti fotograafia näitus "Private: Contemporary Photo Art in Latvia" Riias 20. augustist 18. oktoobrini 2009, kuraator Alise Tifentāle. Lähemalt Arnis Balčus'i, Gunārs Binde, Zenta Dzividzinskat'i, Roman Korovini, Inta Ruka, Alnis Stakle, Vilnis Vītoliņš'i loomingust

  11. 新疆清真风味手撕椒麻鸡加工工艺及其调味配方研究%Research on Xinjiang Islamic Flavor Hand-tom Chicken with Chili Sauce and Seasoning Formula Processing Technology

    Institute of Scientific and Technical Information of China (English)

    王林; 田俊; 平学仁

    2012-01-01

    The author aims to develop the convenience and instance of Xinjiang Islamic Flavor Hand-tom Chicken with Chili Sauce, through the research on the chicken curing, time and temperature of marinating and cooling time, at the same time, using combinative way of frontage and intersection to design and optimize its process techniques, and find the best time list: halogen time for 35mins twice, cooling time is 4min, salt amount of salt added 3.5:4.5 is the optimal combination. Through the orthogonal experiment study of 4 kinds of main flavoring opponents tore Pepper-spiced chicken color, aroma, taste and so on ultimately determine the best formula Pepper-spiced chicken seasoning by weight meter: pepper chiekenl00, pepper oi1128, sesame oil 312 ' salt sesame paste in 5, chicken powder10, monosodium glutamate5 and garlic5.%以改进新疆清真风味手撕椒麻鸡的方便速食性为主要研究目标,对鸡肉腌渍、卤制温度与时间、冷却时间等因素的研究.采用正交组合设计优化手撕椒麻鸡加工工艺,结果表明,卤制温度为80℃,卤制时间为35分钟,二次冷却时间为4分钟,食盐使用量为腌制食盐添加量为3.5:4.5是最佳组合。通过正交试验研究4种主要调味料对手撕椒庥鸡的色、香、味等方面的影响,最终确定出椒麻鸡的调味最佳配方(按份量计)为:椒麻鸡100份、花椒油12份、辣椒油8份、香油3份、芝麻酱12份、食盐5份、鸡粉10份、味精5份、蒜泥5份。

  12. Caracterización de personas con discapacidad física atendidas en el consultorio 3.: Policlínico "Dr. Tomas Romay". Año 2009 Characterization of persons presenting with physical handicaps seen in No. 3 family physician consulting room from The "Dr. Tomás Romay" Polyclinic during 2009

    Directory of Open Access Journals (Sweden)

    Enrique Arce Morera

    2010-03-01

    Full Text Available Se realizó un estudio descriptivo del trabajo realizado en el servicio de rehabilitación comunitaria en el consultorio médico de familia tipo 1 número 3 del policlínico Dr. "Tomas Romay", a las personas con discapacidades físicas en el año 2009. El método empleado para obtener los datos fue la observación. Se empleó la estadística descriptiva para evaluar el grado de discapacidad física, calculándose así la tasa de prevalencia de discapacidad, donde por cada 1 000 habitantes 63 tenían algún tipo de discapacidad. Según la escala de Bartel que mide la gravedad de la invalidez, del total de las personas estudiadas con discapacidades, 108 tenía dificultad en la ejecución de distintas actividades. Recibieron servicios de rehabilitación en su hogar por un personal calificado 5 discapacitados que no podían acudir a los salas de Rehabilitación. Hubo predominio del sexo masculino y el grupo de edades de 60 y más años de edad.A descriptive study was conducted from the work carried out by Community Rehabilitation Service in type 1 No. 3 family physician consulting room from The "Dr. Tomás Romay" Polyclinic, to physically handicapped persons during 2009. Method used to data collection was the observation. Descriptive statistics was used to assess the physical disability level, thus estimating the Handicap Prevalence Rate, where by 1 000 inhabitants, 63 must to have some type of handicap. According to Barlet scale measuring the severity of disability from the total of study handicapped persons. Five handicapped persons that couldn't go the rehabilitation departments received home rehabilitation service by a qualified staff. There was a male sex predominance and of age group of 60 and more years.

  13. Chovendo na roseira de Tom Jobim: uma abordagem schenkeriana Chovendo na roseira by Tom Jobim: a Schenkerian approach

    Directory of Open Access Journals (Sweden)

    Carlos de Lemos Almada

    2010-12-01

    Full Text Available O presente artigo examina a canção Chovendo na roseira, de Antônio Carlos Jobim, focando as relações estruturais aprofundadas existentes entre melodia, harmonia e forma. Isso é realizado através do método da análise schenkeriana, que recebe aqui algumas adaptações, de maneira a se ajustar apropriadamente às características dessa peça específica. Como resultado do processo analítico observa-se uma integração consistente e hierarquizada entre diversos fenômenos melódico-harmônicos presentes na superfície musical e em camadas estruturais internas, revelando relações inusitadas para uma peça de música popular. É especificamente marcante a onipresença do intervalo de quarta justa, infiltrado nos mais diversos aspectos da construção musical, em todos os níveis estruturais observados.The present article examines the song Chovendo na roseira by Brazilian composer Antônio Carlos Jobim with focus on the deep structural relationships that exist among melody, harmony, and form. This was accomplished by using procedures of the Schenkerian analysis, here adapted for better adjustment to the characteristics of this specific piece. From the analytical process, it is possible to observe a consistent and hierarchical integration among the several melodic-harmonic phenomena present on the musical surface and some of the internal layers, which reveal relationships that are unusual in a popular music piece. It is especially remarkable the ubiquity of the interval of the perfect fourth, which is embedded in several of the aspects of musical construction, in all structural levels considered.

  14. Extraction and anticoagulant activity of sulfated polysaccharides from Caulerpa cupressoides var. lycopodium (Vahl C. Agardh (Chlorophyceae - doi: 10.4025/actascibiolsci.v33i2.6243 Extraction and anticoagulant activity of sulfated polysaccharides from Caulerpa cupressoides var. lycopodium (Vahl C. Agardh (Chlorophyceae - doi: 10.4025/actascibiolsci.v33i2.6243

    Directory of Open Access Journals (Sweden)

    Norma Maria Barros Benevides

    2011-05-01

    Full Text Available The reportedly low standard quality of heparin (HEP for use in cardiac surgeries has led to concern in the Brazilian and international markets. Sulfated polysaccharides (SPs from seaweeds have been regarded as promising substitutes for HEP. The aim of this study was to sequentially extract total SPs (TSPs from Caulerpa cupressoides (Chlorophyceae with papain in 100 mM sodium acetate buffer (pH 5.0 containing 5 mM cysteine and 5 mM EDTA, followed by fractionation by ion-exchange chromatography (DEAE-cellulose, and then evaluate the anticoagulant potential of SP fractions by activated partial thromboplastin time (APTT using normal human plasma and compare it to standard HEP (193 IU mg-1. The obtained fractions were chemically characterized by chemical composition and agarose gel electrophoresis. The yield was 4.61%, and three fractions of SP (F I, F II and F III eluted with 0.50, 0.75 and 1.00 M of NaCl, respectively, were observed on chromatography profiles; however, differences in charge densities patterns and degree of resolution among them were revealed by electrophoresis. SPs were capable of modifying APTT only in fractions eluted with 0.75 M of NaCl, whose activities were 23.37 and 25.76 IU mg-1, respectively, and the charge density was prerequisite to activity. Therefore, C. cupressoides is a source of SPs possessing low anticoagulant potential compared to HEP.The reportedly low standard quality of heparin (HEP for use in cardiac surgeries has led to concern in the Brazilian and international markets. Sulfated polysaccharides (SPs from seaweeds have been regarded as promising substitutes for HEP. The aim of this study was to sequentially extract total SPs (TSPs from Caulerpa cupressoides (Chlorophyceae with papain in 100 mM sodium acetate buffer (pH 5.0 containing 5 mM cysteine and 5 mM EDTA, followed by fractionation by ion-exchange chromatography (DEAE-cellulose, and then evaluate the anticoagulant potential of SP fractions by activated partial thromboplastin time (APTT using normal human plasma and compare it to standard HEP (193 IU mg-1. The obtained fractions were chemically characterized by chemical composition and agarose gel electrophoresis. The yield was 4.61%, and three fractions of SP (F I, F II and F III eluted with 0.50, 0.75 and 1.00 M of NaCl, respectively, were observed on chromatography profiles; however, differences in charge densities patterns and degree of resolution among them were revealed by electrophoresis. SPs were capable of modifying APTT only in fractions eluted with 0.75 M of NaCl, whose activities were 23.37 and 25.76 IU mg-1, respectively, and the charge density was prerequisite to activity. Therefore, C. cupressoides is a source of SPs possessing low anticoagulant potential compared to HEP.

  15. Depreciação no Brasil e na Alemanha: as diferenças na aplicação a um tomógrafo e construção anexa = Depreciation in Brazil and Germany: differences in a Ct Scan and an Attached Building

    Directory of Open Access Journals (Sweden)

    Charles Albino Schultz

    2009-03-01

    Full Text Available O presente estudo é uma análise das diferentes abordagens da depreciação na legislação fiscal no Brasil e na Alemanha. Foi realizada por meio de um estudo descritivo que simula a aplicação das diferentes fórmulas de cálculo das parcelas de depreciação deum tomógrafo e da construção anexa em um hospital universitário público e um hospital privado. A legislação fiscal brasileira mostrou-se mais simples que a alemã, contudo, ao mesmo tempo, permite um número indefinido de alternativas de depreciação, por ser possível a adoção de fórmulas de cálculo diferentes das especificadas na legislação. Além disso, constatou-se a ausência de uma legislação sobre a depreciação em instituições públicas. Já, na Alemanha, a legislação permite mais fórmulas de cálculo, entretanto, com parâmetros rígidos de enquadramento em determinados métodos utilizados como incentivo. A utilização da depreciação como forma de atribuir incentivos à renovação tecnológica e ao desenvolvimento de setores específicos é idêntica em ambos os países e, normalmente, é exercida por meio da depreciação acelerada. Uma característica específica da legislação alemã consiste no fato desta ser aplicada tanto a hospitais particulares quanto a hospitais públicos, enquanto que no Brasil a depreciação é exclusiva à contabilidade das empresas privadas.This study is an analysis of several different approaches of the reduction of the taxlegislation in Brazil and Germany. It was accomplished through a descriptive study thatsimulates the application of different formulas for calculating depreciation of portionsof a CT scan and the building attached to a public university hospital and a privatehospital. The Brazilian tax legislation proved to be simpler than the German, however,at the same time it allows an indefinite number of alternatives for depreciation, once itis possible the adoption of different formulas for calculating from

  16. On the Translation of Mark Twain’s Children’s Literature in China---A Case Study on the Chapter One of Zhang Yousong’s Translation of The Adventures of Tom Sawyer%浅析马克·吐温儿童文学作品在中国的翻译--以张友松《汤姆·索亚历险记》汉译本第一章为例

    Institute of Scientific and Technical Information of China (English)

    黄玉霞

    2014-01-01

    儿童文学翻译研究几乎处于文学研究边缘地位,为了解马克·吐温儿童文学著作在中国的翻译,文章以张友松的《汤姆·索亚历险记》汉译本为考察对象,研究其译本的语言特点。通过分析发现:张友松翻译的语言受两大因素影响:一是他自身的翻译思想,二是儿童文学翻译特点。张友松用富有儿童特色的语言绘声绘色地将儿童心理、儿童生活描写出来,更活灵活现地刻画了各色人物的性格特征,从而激起儿童的兴趣和共鸣。%It is widely acknowledged that the scholars pay little attention to the study of children’s liter-ature translation for such a long time. In order to learn more about the translation of Mark Twain’s Children’ s Literature in China, the paper explores The Adventures of Tom Sawyer translated by Zhang Yousong. This paper aims to investigate Zhang’s translation strategies. With a comprehensive study, this paper finds out that Zhang’s translation is mainly affected by two factors: the first reason is Zhang’s own translation theory, and the other one is the specific characteristics of children’s literature translation. On the whole, Zhang de-scribes children’s psychological activities and life in a specific language with children’s characteristics. Moreover, he depicts different traits of character vividly, thus it arouses children's interest and empathy.

  17. Evaluación ambiental de los fondos documentales de la biblioteca Tomás Navarro Tomás del CCHS-CSIC

    Directory of Open Access Journals (Sweden)

    Peña-Poza, Javier

    2011-03-01

    Full Text Available The most innovative procedure for preventive conservation of library holdings, especially those of historical interest, lies in the evaluation of environmental parameters witch have a negative effect on the conservation of such materials. The application of sensors permits for full, accurate and secure monitoring of environmental conditions and allows for the prediction of chemical-physical mechanisms of degradation, as well as of the most suitable procedures for controlling them. The sensors used in the present study were prepared by the sol-gel method and change colour when variations in the evaluated parameters occur. All of the sensors are reversible, reusable and can be regenerated. Temperature, relative humidity, illumination and acidity were the parameters evaluated. In the first stage, conventional apparatus were used to determine the critical ranges of variation for such parameters. Subsequently optical sensors sensitive in such ranges were designed and prepared. These sensors were calibrated and distributed throughout the rooms containing the holdings (approximately 3.200 square meters. The optical response of the sensors (change of colour was recorded by visible spectrophotometry during the spring and summer of 2009. The use of sensors has the following advantages: low cost, no need for wires or apparatus during exposure, small size, reversibility, and short response time. The resulting data have revealed the environmental conditions of the conservation of the holdings, including environmental acidity, a parameter that could not be evaluated previously through conventional procedures.

    El procedimiento más innovador de conservación preventiva de los fondos documentales de bibliotecas, especialmente los de carácter histórico, consiste en la evaluación de los parámetros ambientales que afectan negativamente a la conservación de los materiales implicados. La aplicación de sensores permite la monitorización completa, precisa y segura de las condiciones ambientales, predecir los mecanismos quimicofísicos de degradación y los procedimientos más adecuados para controlarlos. Los sensores de este estudio se prepararon por el procedimiento sol-gel y experimentan un cambio de color cuando varían los parámetros a evaluar. Todos los sensores son reversibles, regenerables y reutilizables. Los parámetros evaluados han sido temperatura, humedad relativa, iluminación y acidez. En la primera etapa se utilizaron aparatos convencionales para determinar los intervalos críticos de variación de dichos parámetros. Posteriormente se diseñaron y prepararon sensores ópticos con sensibilidad en esos intervalos, se calibraron y se distribuyeron en las salas de los fondos documentales (aproximadamente 3.200 m2. La respuesta óptica de los sensores (cambio de color se registró mediante espectrofotometría visible durante la primavera-verano de 2009. El uso de estos sensores presenta las siguientes ventajas: bajo coste, ausencia de cables y aparatos durante la exposición, pequeño tamaño, reversibilidad y tiempos cortos de respuesta. Los resultados han permitido conocer las condiciones ambientales de conservación de los fondos documentales, incluyendo la acidez ambiental que hasta ahora no es posible evaluar con los procedimientos convencionales disponibles.

  18. Kumar et al., Afr J Tradit Complement Altern Med. (2013) 10(6):426 ...

    African Journals Online (AJOL)

    cadewumi

    Validated modified lycopodium spore method has been developed for simple ... In the case of powdered drugs the standard methods like ash value, extractive ... Modified Lycopodium spore method is an important analytical technique for powdered drug, especially when other methods of ... Leica DMLS-2 Instrumentation.

  19. La eticidad de la política según Santo Tomás

    OpenAIRE

    1997-01-01

    1. La Politica Como Saber Moral En Santo Tomas. 2. Fundamentos De La Proyeccionpolitica De La Moral: Teoria Del Orden; Teoria De La Justicia; Teoria De La Ley.3. El Pensamiento De Santo Tomas Y Las Exigencias Contemporaneas De Unamoralidad Politica.

  20. The effect of light intensity on growth and development of turkey toms.

    Science.gov (United States)

    Yahav, S; Hurwitz, S; Rozenboim, I

    2000-03-01

    1. The effect of light intensities from 10 to 700 lux on the performance of 5 to 18 week-old turkey males was studied in 2 trials. 2. Body weight of 18 week-old turkeys, in both experiments, was highest under the lowest light intensity This coincided with higher weight gain and lower food intake, which resulted in significantly better food conversion efficiency 3. Light intensity affected heart muscle weight but not weight of breast muscle, abdominal fat or testis as proportions of body weight. 4. The decline in plasma T3 concentration with age differed from other treatments at the low light intensity, which resulted in a significantly higher T3 concentration in turkeys exposed to 10 lux at the age of 10 to 15 weeks. 5. It is concluded that light intensity significantly affects food conversion efficiency in turkey males. This is likely to be related to differential investment of energy expenditure for maintenance.

  1. Tom W. Bonner Prize in Nuclear Physics Talk: Finding Real Nuclei in Imaginary Time

    Science.gov (United States)

    Pieper, Steven C.

    2010-02-01

    Ab initio calculations of nuclei treat a nucleus as a system of A nucleons interacting by realistic two- (N ) and three-nucleon (N ) forces. Variational Monte Carlo (VMC) followed by Green's function Monte Carlo (GFMC) is a very successful ab initio method for light nuclei. The VMC gives an upper bound to the true energy of a nucleus for a given Hamiltonian; the closeness of the upper bound to the exact solution of the Schr"odinger equation depends on the physical insight built into the trial wave function, ψT, that is used. GFMC starts with a ψT and, by propagation in imaginary time, allows the exact lowest eigenenergy for a given set of quantum numbers to be computed. The first VMC calculations of nuclei were published in 1981 by Lomnitz-Adler, Pandharipande, and Smith. They were for ^3H and ^4He using the Reid N potential. Six years later, Carlson published the first GFMC calculations of nuclei, again for ^3H and ^4He, but using a slightly-simplified N potential; in the following year he used the full Reid V8 potential. Pudliner, Pandharipande, Carlson, and Wiringa published GFMC calculations of A=6 nuclei in 1995, using the Argonne V18 N potential and the Urbana IX N potential. Since then there has been steady progress in applying GFMC to larger nuclei. This has been from both increasing computer power and new or improved algorithms. The largest computers are increasingly difficult to use efficiently, but, as a result of a SciDAC collaboration, we now get excellent scalability up to 131,000 cores on Argonne's IBM Blue Gene/P. In addition we have found that the GFMC can be used for multiple states with the same quantum numbers. With the Argonne V18 and Illinois N potentials, we obtain an excellent description of the properties of nuclei up to A = 12. I will describe these methods, present recent advances in using the largest computers, and some recent results. )

  2. Tom Brown’s schooldays: ‘sportsex’ in Victorian Britain

    OpenAIRE

    Harvey, Andy

    2012-01-01

    Thomas Hughes’ idealised vision of life at Rugby public school is one of the best-known novels in the English language. It was regarded from the outset as a founding text of ‘muscular Christianity’. Contrary to the intentions of its author, it helped to inaugurate the cult of ‘manly’ athleticism that swept through the English public schools in the second half of the nineteenth-century. I argue that the novel reveals tensions around gender and sexuality that were in play among public schoolboy...

  3. International relations among Tom Thumbs: Taiwan as provider of aid Central America

    Directory of Open Access Journals (Sweden)

    Francisco Javier Haro Navejas

    2007-06-01

    Full Text Available This paper analyzes the Official Development Aid (AOD that has as its source Taiwan and as its destination Central America. It has three basic aims: Firstly, there is a huge bibliographic vacuum on the topic of these pages. Beginning filling it is an academic need. Even some intellectuals feel that they should lean against either Beijing or Taipei, that if they write on Taiwan they should defend or attack one of the contending parties. Here it is seen that a study close to objectivity is possible. Secondly, most of the research in International Relations has been focused on topics related with power itself or with just elements related with hard power. AOD is both hard and soft power, therefore this paper shades light to the dark side partially viewing international relations from a theoretical perspective were interactions help to construct identities and cooperation is an essential variable of world politics. Finally, it will be seen below that the Taiwanese cooperativeeconomic actions are helpful to the progress of poor parts of the Central American region and are helpful to create domestic markets with strong links with the world market deepening the economic integration both regional and global. Aid from Taiwan and some other countries, mainly through the transmission of know how, could be of assistance in surmounting huge troubles. Aid is vital because some of Central American’s problems are being exported mainly to México and the United States under the form, just to give an example, of Mara Salvatrucha gangs source of violence and drug trafficking. It is not meaningless to stress that Taiwanese ODA is by far not enough and is very small in the international context.

  4. Inmortalidad e Intelección según Tomás de Aquino

    Directory of Open Access Journals (Sweden)

    David Ezequiel Téllez Maqueo

    2013-11-01

    Full Text Available After a brief discussion and some conclusions on the meaning of the eternity and inmortality of the soul according to Aristotle, the paper tries to show some differences between Aristotle's and Aquinas's approaches to the subject,

  5. Price rules in airline marketing / Elina Krauja-Veide, Marina Jõgi, Toms Andersons...[jt.

    Index Scriptorium Estoniae

    2004-01-01

    Lennukompaniide Air Baltic, Estonian Air, British Airways ja Lithuanian Airlines turundusjuhid olukorrast Baltimaade lennundusturul ja lennufirmade turundustegevusest. Kommenteerivad Priit Kivik, Ilona Kbejan, Julia Brjuhanova. Tabel

  6. Keskerakond tasub slovaki annetuste eest Brüsselis / Tom Nicholson

    Index Scriptorium Estoniae

    Nicholson, Tom

    2009-01-01

    Autori väitel on Slovakkia ärimeeste mitmekümne tuhande euro suurune annetus Keskerakonnale seotud Slovakkia Rahvapartei püüdlusega ühineda Euroopa Parlamendi ALDE fraktsiooniga. Keskerakond on ALDE liige

  7. Minors and informed consent : a comparative approach / Loes Sultiens, Tom Goffin, Pascal Borry...[jt.

    Index Scriptorium Estoniae

    2007-01-01

    Euroopa Nõukogu "Inimõiguste ja biomeditsiini konventsiooni" artikli 6 (Nõusoleku andmiseks võimetu isiku kaitse) täitmise võrdlev analüüs erinevate Euroopa riikide siseriikliku õiguse kontekstis. Eesti kohta lk. 26-27

  8. "Siin on põrsad, kuid minge ka allkorrusele." / Toms Ancitis

    Index Scriptorium Estoniae

    Ancitis, Toms

    2010-01-01

    Eesti, Läti ja Leedu paviljonidest EXPO maailmanäitusel Shanghais (1. mai - 31. oktoober 2010). Näituse teemaga "Parem linn, parem elu" juhitakse tähelepanu kiire linnastumisega kaasnevatele probleemidele

  9. Yo, Tomás Cipriano de Mosquera: de Mario H. Perico Ramírez

    Directory of Open Access Journals (Sweden)

    Alberto Pérez Rojas

    1968-12-01

    Full Text Available Apasionante este magnífico ensayo de biografía de uno de los más notables hombres públicos colombianos del siglo XIX, que se lee de un tirón, pues desde las primeras líneas despierta inusitado interés. El primer acierto de Perico Ramírez, escritor que con frecuencia nos sorprende y nos regala con obras de especial calidad literaria, es, sin duda, la idea de haberlo escrito en primera persona, es decir, haciendo hablar al general como si en realidad, en sus últimos años y después de su agitadísima vida, hubiera resuelto, desde su retizo de Coconuco, redactar sus memorias. Tal es la impresión que el lector siente, impresión tan real que se ve al personaje pleno de senectud y de achaques pero aún imbuído de la soberbia increíble que fue el predominante de sus rasgos sicológicos. Por fuera mostrando los estragos físicos de 80 años vividos con intensidad asombrosa pero "por dentro todavía fresco, casi nuevo".

  10. The relationship between sperm function and diet: toms are what they eat

    Science.gov (United States)

    It is well known that cryopreserved semen could be used to regenerate commercial or research poultry lines; however, fertility rates from poultry semen frozen with current methods are not reliable enough for germ-line retrieval, especially from lines with low reproductive efficiency. As part of a l...

  11. Trafficking of Human Beings from a Human Rights Perspective. Towards a Holistic Approach, Tom Obokata

    Directory of Open Access Journals (Sweden)

    Laurence Husson

    2011-11-01

    Full Text Available Cet ouvrage, comme l’indique clairement son titre, concerne le trafic d’êtres humains, phénomène aussi courant que répandu de nos jours, et qui tire son origine d’anciennes pratiques comme l’esclavage, le servage ou même de la « traite des Blanches ». Il concernerait, chaque année, à l’échelle de la planète, entre 600 000 et 800 000 personnes, femmes et enfants pour la plupart et représenterait un marché extrêmement lucratif. L’auteur se concentre sur la traite contemporaine, favorisée par pl...

  12. Capilla San Manuel de La Estrella, Pudahuel, Chile.: Tomás Browne, Alberto Browne, 2013.

    OpenAIRE

    Browne,Alberto

    2014-01-01

    En muchos barrios de la periferia urbana chilena la pieza edilicia más significativa es un colegio o una iglesia. Esta capilla emplazada en una esquina de Pudahuel provee a la comunidad de un espacio interior cuidado y calmo para dar lugar a la reunión y el encuentro.

  13. Minors and informed consent : a comparative approach / Loes Sultiens, Tom Goffin, Pascal Borry...[jt.

    Index Scriptorium Estoniae

    2007-01-01

    Euroopa Nõukogu "Inimõiguste ja biomeditsiini konventsiooni" artikli 6 (Nõusoleku andmiseks võimetu isiku kaitse) täitmise võrdlev analüüs erinevate Euroopa riikide siseriikliku õiguse kontekstis. Eesti kohta lk. 26-27

  14. Os emergentes emergem e determinam o novo tom da política internacional?

    Directory of Open Access Journals (Sweden)

    GUNTHER RUDZIT

    2009-03-01

    Full Text Available

    A crise econômica traz a necessidade de

    cooperação e pode ser a oportunidade dos países

    emergentes modificarem as instituições internacionais.

  15. En torno a la servidumbre natural en Tomás de Aquino

    Directory of Open Access Journals (Sweden)

    Héctor Velázquez F.

    2013-11-01

    Full Text Available The basic aim of this work is to highlight the structure which Thomas Aquinas finds in Aristotle's Politics on natural servitude, trying to recover the doctine defended by the Philosopher and commented by St. Thomas,

  16. Richard Wright's Successful Failure: A New Look at "Uncle Tom's Children"

    Science.gov (United States)

    Giles, James R.

    1973-01-01

    A reevaluation of novelist Richard Wright's first book, which is a collection of five short stories-- Big Boy Leaves Home,'' Down by the Riverside,'' Long Black Song,'' Fire and Cloud,'' and Bright and Morning Star''--and an introductory essay, The Ethics of Living Jim Crow.'' (JM)

  17. Tom ja Anni ajavad isad-emad naerma / Kai Väärtnõu

    Index Scriptorium Estoniae

    Väärtnõu, Kai

    2007-01-01

    ETV lastesaate "Saame kokku Tomi juures" stsenarist on Jaak Urmet ehk Wimberg. Teksti improviseerivad ka näitlejad Karol Kuntsel ja Maria Soomets. Lisaks tutvustus "Pööningule purjetab proua Õietolmutuust"

  18. "Siin on põrsad, kuid minge ka allkorrusele." / Toms Ancitis

    Index Scriptorium Estoniae

    Ancitis, Toms

    2010-01-01

    Eesti, Läti ja Leedu paviljonidest EXPO maailmanäitusel Shanghais (1. mai - 31. oktoober 2010). Näituse teemaga "Parem linn, parem elu" juhitakse tähelepanu kiire linnastumisega kaasnevatele probleemidele

  19. Tom W. Bonner Prize in Nuclear Physics Talk: Symmetries and Simple Patterns in Nuclei

    Science.gov (United States)

    Casten, Richard

    2011-04-01

    Nuclei are complex many-body objects that display remarkably simple patterns and regularities, both for a given nucleus and across regions of nuclei. The juxtaposition of these two facets of nuclear structure is reflected in two general, and complementary, approaches to their description - a microscopic (femtoscopic, of course) perspective in terms of the motions of the individual nucleons and their interactions, and a macroscopic view of the nucleus as a whole, in terms of its shapes, symmetries, and collective behavior. The first part of this talk will discuss the simple patterns nuclei exhibit and interpret them in terms of symmetries, such as those of the Interacting Boson Approximation (IBA) model, elementary collective modes, changes in shell structure, and quantum phase transitions in the equilibrium structure. It is also possible to approach structural evolution in nuclei with an extremely simple, more microscopic, perspective focusing on the competition of the most important residual interactions, pairing and the valence proton-neutron (p - n) interaction. While this is not a substitute for a comprehensive theoretical treatment, which remains a challenge and goal of nuclear theory, such an analysis leads to simple approaches, such as the NpNn scheme and the P-factor, that correlate large amounts of nuclear data, can guide estimates of unknown nuclei, and which are highly sensitive indicators of changes in shell structure and of nuclei that exhibit behavior deviating from normal tends. Finally, empirical means of extracting information on the critical valence p - n interaction will be discussed and the systematic behavior of these interaction strengths will be linked to shell structure on the one hand, and the onset and development of collectivity on the other. Work supported by the US DOE under Grant No. DE-FG02-91ER-40609.

  20. Dichte kassen stellen hogere eisen aan luchtkwaliteit (interview met Tom Dueck)

    NARCIS (Netherlands)

    Arkesteijn, M.; Dueck, T.A.

    2012-01-01

    Planten hebben CO2 nodig voor hun fotosynthese. Maar afhankelijk van welke CO2-bron kunnen er ook (rook) gassen mee de kas in komen, met een averechts effect op de groei en productkwaliteit. Wat is de laatste stand van zaken wat betreft deze schadelijke gassen. En hoe kunnen telers meer inzicht krij

  1. Raymond Carver: Vandali / S engleskog prevela Ana Tomčić

    Directory of Open Access Journals (Sweden)

    Raymond Carver

    2011-12-01

    Full Text Available Carol i Robert Norris bili su stari prijatelji Nickove žene Joanne. Upoznali su se davno, mnogo prije nego što je ona upoznala Nicka. Poznavali su je kada je bila udana za Billa Dalyja. U ono vrijeme njih četvero – Carol i Robert, Joanne i Bill – friško oženjeni studenti na zadnjoj godini povijesti umjetnosti – živjeli su u istoj kući, velikoj kući na Seattleovoj verziji Capitol Hilla, dijelili stanarinu i kupaonicu. Često su zajedno jeli i sjedili do sitnih sati, pili vino i razgovarali. Jedni su drugima pregledavali i komentirali radove. Tijekom te zadnje godine zajedničkog života – prije nego što se pojavio Nick – čak su kupili jeftin brodić kojim su ljeti zajedno plovili jezerom Washington. “Kakva su to vremena bila, i dobra i loša, puna uspona i padova”, rekao je Robert drugi put toga jutra osmjehujući se i promatrajući lica prijatelja za stolom. Bila je nedjelja ujutro, a oni su sjedili za stolom u kuhinji Nicka i Joanne u Aberdeenu i jeli dimljeni losos, kajganu i peciva sa sirnim namazom. Bio je to onaj isti losos kojeg je Nick uhvatio prošlog ljeta i vakumirao i stavio u duboko zamrzavanje. Sviđalo mu se kad je Joanne naglasila da je on sam ulovio tu ribu. Čak je znala – ili je barem tvrdila da zna – koliko je teška. “Ova je imala osam kila”, rekla je, a Nick se zadovoljno nasmijao. Sinoć je izvadio ribu iz zamrzivača nakon što je nazvala Carol i rekla da bi ona i Robert rado svratili sa svojom kćerkicom Jenny kad budu u prolazu.

  2. Visual Archaeology: Cultural Change Reflected by the Covers of "Uncle Tom's Cabin"

    Science.gov (United States)

    Fee, Samuel B.; Fee, Tara R.

    2012-01-01

    In this paper, we describe the merits of "visual archaeology," or understanding the past through the analysis of images, as a method for teaching historical context. We begin by articulating the typical archaeological process for studying and analyzing material artifacts, and then describe the possibilities this process offers for…

  3. Social infrastructure to integrate science and practice: the experience of the Long Tom Watershed Council

    Science.gov (United States)

    Rebecca L. Flitcroft; Dana C. Dedrick; Courtland L. Smith; Cynthia A. Thieman; John P. Bolte

    2009-01-01

    Ecological problem solving requires a flexible social infrastructure that can incorporate scientific insights and adapt to changing conditions. As applied to watershed management, social infrastructure includes mechanisms to design, carry out, evaluate, and modify plans for resource protection or restoration. Efforts to apply the best science will not bring anticipated...

  4. Price rules in airline marketing / Elina Krauja-Veide, Marina Jõgi, Toms Andersons...[jt.

    Index Scriptorium Estoniae

    2004-01-01

    Lennukompaniide Air Baltic, Estonian Air, British Airways ja Lithuanian Airlines turundusjuhid olukorrast Baltimaade lennundusturul ja lennufirmade turundustegevusest. Kommenteerivad Priit Kivik, Ilona Kbejan, Julia Brjuhanova. Tabel

  5. Tom W. Bonner Prize in Nuclear Physics Lecture: The limits of nuclear landscape

    Science.gov (United States)

    Nazarewicz, Witold

    2012-03-01

    Understanding nuclei is a quantum many-body problem of incredible richness and diversity and studies of nuclei address some of the great challenges that are common throughout modern science. Nuclear structure research strives to build a unified and comprehensive microscopic framework in which bulk nuclear properties, nuclear excitations, and nuclear reactions can all be described. A new and exciting focus in this endeavor lies in the description of exotic and short-lived nuclei at the limits of proton-to-neutron asymmetry, mass, and angular momentum. In this talk, advances in the nuclear density functional theory will be reviewed in the context of the main scientific questions, experimental developments, and the advent of extreme-scale computing platforms.

  6. A Community Terrain-Following Ocean Modeling System (ROMS/TOMS)

    Science.gov (United States)

    2013-09-30

    derived from the adjoint of 4D-Var, Mon. Weather Rev., 140, 3183-3203. Zavala -Garay, J., J.L. Wilkin, and H.G. Arango, 2012: Predictability of...Edwards, K.W. Bruland, E. Di Lorenzo , C.V.W Lewis, T.M. Powell, E. Curchitser, and K. Hedstrom, 2009: Modeling iron limitation of primary production in...press (online early view). Haidvogel, D.B., H. Arango, W.P. Budgell, B.D. Cornuelle, E. Curchitser, E. Di Lorenzo , K. Fennel, W.R. Geyer, A.J. Hermann

  7. Richard Wright's Successful Failure: A New Look at "Uncle Tom's Children"

    Science.gov (United States)

    Giles, James R.

    1973-01-01

    A reevaluation of novelist Richard Wright's first book, which is a collection of five short stories-- Big Boy Leaves Home,'' Down by the Riverside,'' Long Black Song,'' Fire and Cloud,'' and Bright and Morning Star''--and an introductory essay, The Ethics of Living Jim Crow.'' (JM)

  8. Tere, sa räägid oma unelmatekoduga / Tom Rhodes

    Index Scriptorium Estoniae

    Rhodes, Tom

    2000-01-01

    Los Angeleses tulid müügile kõrgtehnoloogilised majad, mille hinnad algavad 160 miljonist kroonist. Valida saab männipuust mööbliga inglise maakodu, toskaana villa, prantsuse kuningalossi, New Yorgi katuselamu vahel. Kogu sisustus on disaineri kujundatud. Kõik asjad on ühendatud keskarvutiga.

  9. Tom ja Anni ajavad isad-emad naerma / Kai Väärtnõu

    Index Scriptorium Estoniae

    Väärtnõu, Kai

    2007-01-01

    ETV lastesaate "Saame kokku Tomi juures" stsenarist on Jaak Urmet ehk Wimberg. Teksti improviseerivad ka näitlejad Karol Kuntsel ja Maria Soomets. Lisaks tutvustus "Pööningule purjetab proua Õietolmutuust"

  10. Tom Bonner Prize: Gamma-ray energy tracking array GRETINA and its early science results

    Science.gov (United States)

    Lee, I.-Yang

    2016-03-01

    Gamma-ray detector with good energy resolution has been one of the essential instruments for the study of nuclear structure. To push these studies toward the exotic nuclei near the particle stability line, we need detectors with higher peak efficiency and good peak-to-total ratio. In addition, radioactive ion beams needed for such studies are often produced by the projectile fragmentation method. They have high velocities, and detectors must provide adequate position resolution for accurate Doppler correction. To fulfill these requirements, the new concept of gamma ray energy tracking array was developed. GRETINA, with 1 π solid angle coverage, is the first implementation of this concept. It uses electrically segmented Ge crystals in a close packed geometry, fast digital electronics, and signal decomposition to determine the position and energy of the individual interaction points. Then the path of a gamma ray can be tracked using the angle-energy relation of the scattering process. GRETINA was completed at LBNL and started physics operation in 2012. It has been used at NSCL at MSU and ATLAS at ANL for a large number of experiments addressing diverse topics from nuclear structure to nuclear astrophysics. In this talk I will describe the concept of gamma-ray energy tracking and the technology developed for GRETINA. A few representative experiments showing the breadth of the science and the power of the instrument will be discussed. Finally the plan toward the full 4 π array GRETA will be presented.

  11. Polymer materials for roll coated solar cells: strategies tom improve performance and stability

    DEFF Research Database (Denmark)

    Heckler, Ilona Maria

    Solar cells are among the renewable energy technologies with a large potential in terms of solar energy availability. The solar cells based on conjugated polymers belong to the third generation of this technology and their attractive features include a fast and cheap solution‐processed production...

  12. Keskerakond tasub slovaki annetuste eest Brüsselis / Tom Nicholson

    Index Scriptorium Estoniae

    Nicholson, Tom

    2009-01-01

    Autori väitel on Slovakkia ärimeeste mitmekümne tuhande euro suurune annetus Keskerakonnale seotud Slovakkia Rahvapartei püüdlusega ühineda Euroopa Parlamendi ALDE fraktsiooniga. Keskerakond on ALDE liige

  13. Realización de un Tomógrafo Óptico Coherente

    OpenAIRE

    2007-01-01

    187 páginas.-- Proyecto fin de carrera (PTF) presentado en el Dpto de Ingeniería Electrónica de la Escula Politécnica Superior de Ingeniería de Telecomunicaciones de la Universidad de Alcalá (UAH) y realizado en el Dpto de Metrología del Instituto de Física Aplicada del CSIC (IFA-CSIC).

  14. UniProt search blastx result: AK287459 [KOME

    Lifescience Database Archive (English)

    Full Text Available oroplast (EC 1.6.5.-) (NAD(P)H dehydrogenase subunit I) (NDH subunit I) (NADH-plastoquinone oxidoreductase subunit I) - Huperzia lucidula (Shining clubmoss) (Lycopodium lucidulum) 0 ...

  15. International Journal of Biological and Chemical Sciences - Vol 4 ...

    African Journals Online (AJOL)

    Long-term effect of Mali phosphate rock on the grain yield of interspecifics and .... of Lycopodium clavatum in reducing induced hepatotoxicity and genotoxicity in ... Analysis of heavy metals in roadside soils and crops along the Obansandjo ...

  16. Did Hahnemann plagiarize Aquinas? Hahnemann plagió Tomás de Aquino? Hahnemann plagiu Tomás de Aquino?

    Directory of Open Access Journals (Sweden)

    Silvia Waisse Priven

    2004-01-01

    Full Text Available The use of historiographical methods may be of profit in elucidating homeopathic theory. As case study, Masi Elizalde’s controversial hypothesis concerning a supposed plagiarism of a Thomas Aquinas’ text by Hahnemann is analysed. Philological comparison, analysis of historical context and the application of the most modern approaches in the History of Science are shown as useful tools.

  17. eTom/SOA的数字汇流运营支撑系统及流程实现%eTom / SOA for the Digital Convergence Operation Support System and Process Implementation

    Institute of Scientific and Technical Information of China (English)

    黄振益; 徐俊傑

    2011-01-01

    In order to realize the digital convergence business integration of operational management needs, we propose an architecture which uses the enhanced telecom operations map model structure of telemanagement forum and service-oriented architecture for design core. The architecture fulfills the future digital convergence business oriented requirements to construct the completed operation support system( OSS), and analyze instructions architecture constitute modules and related subsystems. In addition,using web services interface the service network component interface and information transmission standardization are built. Therefore, this architecture can provide a framework of recommendation and referenee for customer service order process flow description based on digital convergence networks service operation support system.%为了实现数字汇流业务融合的运营管理需求,符合未来数字融合业务导向的需求,以电信管理论坛的增强型电信运营图模型结构和面向服务的体系结构为设计核心,建构完整的运营支撑系统(OSS),分析说明了体系结构中的构成模块和相关子功能,利用web服务建立服务网络组件接口和信息传递标准化,并通过客户服务订单流程场景说明,对数字汇流网络下的服务OSS提供了架构面的建议与参考.

  18. CERES AuTomAted job Loading SYSTem (CATALYST): An automated workflow manager for satellite data production

    Science.gov (United States)

    Gleason, J. L.; Hillyer, T. N.; Wilkins, J.

    2012-12-01

    The CERES Science Team integrates data from 5 CERES instruments onboard the Terra, Aqua and NPP missions. The processing chain fuses CERES observations with data from 19 other unique sources. The addition of CERES Flight Model 5 (FM5) onboard NPP, coupled with ground processing system upgrades further emphasizes the need for an automated job-submission utility to manage multiple processing streams concurrently. The operator-driven, legacy-processing approach relied on manually staging data from magnetic tape to limited spinning disk attached to a shared memory architecture system. The migration of CERES production code to a distributed, cluster computing environment with approximately one petabyte of spinning disk containing all precursor input data products facilitates the development of a CERES-specific, automated workflow manager. In the cluster environment, I/O is the primary system resource in contention across jobs. Therefore, system load can be maximized with a throttling workload manager. This poster discusses a Java and Perl implementation of an automated job management tool tailored for CERES processing.

  19. Tomáš Sedláček: l’economia del bene e del male

    Directory of Open Access Journals (Sweden)

    Maria Chiara Pievatolo

    2014-06-01

    Full Text Available Un sabato fatto per l’uomo Alla fine di ogni settennio concederai la remissione. Questa è la regola della remissione: ogni creditore rimetterà ciò che verrà prestato al suo prossimo; non costringerà al pagamento né il suo prossimo né il suo...

  20. Spirituaalne ruum vaimsuse otsingutes = Sacred spaces as a medium for connecting people in their search for spirituality / Tom Callebaut

    Index Scriptorium Estoniae

    Callebaut, Tom

    2015-01-01

    Essees vaadeldakse arhitektuuri kui vahendit pakkumaks inimestele võimalust luua oma spirituaalne nägemus ja kogemus. Spirituaalse ruumi loomisel võetakse aluseks, et luuakse koht, kus inimestele antakse võimalus arendada individuaalselt või kollektiivselt oma spirituaalset identiteeti.