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Sample records for lung sound monitoring

  1. Portable system for auscultation and lung sound analysis.

    Science.gov (United States)

    Nabiev, Rustam; Glazova, Anna; Olyinik, Valery; Makarenkova, Anastasiia; Makarenkov, Anatolii; Rakhimov, Abdulvosid; Felländer-Tsai, Li

    2014-01-01

    A portable system for auscultation and lung sound analysis has been developed, including the original electronic stethoscope coupled with mobile devices and special algorithms for the automated analysis of pulmonary sound signals. It's planned that the developed system will be used for monitoring of health status of patients with various pulmonary diseases.

  2. Towards the standardisation of lung sound nomenclature

    NARCIS (Netherlands)

    Pasterkamp, Hans; Brand, Paul L. P.; Everard, Mark; Garcia-Marcos, Luis; Melbye, Hasse; Priftis, Kostas N.

    Auscultation of the lung remains an essential part of physical examination even though its limitations, particularly with regard to communicating subjective findings, are well recognised. The European Respiratory Society (ERS) Task Force on Respiratory Sounds was established to build a reference

  3. Reduction of heart sound interference from lung sound signals using empirical mode decomposition technique.

    Science.gov (United States)

    Mondal, Ashok; Bhattacharya, P S; Saha, Goutam

    2011-01-01

    During the recording time of lung sound (LS) signals from the chest wall of a subject, there is always heart sound (HS) signal interfering with it. This obscures the features of lung sound signals and creates confusion on pathological states, if any, of the lungs. A novel method based on empirical mode decomposition (EMD) technique is proposed in this paper for reducing the undesired heart sound interference from the desired lung sound signals. In this, the mixed signal is split into several components. Some of these components contain larger proportions of interfering signals like heart sound, environmental noise etc. and are filtered out. Experiments have been conducted on simulated and real-time recorded mixed signals of heart sound and lung sound. The proposed method is found to be superior in terms of time domain, frequency domain, and time-frequency domain representations and also in listening test performed by pulmonologist.

  4. Effects of lung elasticity on the sound propagation in the lung

    International Nuclear Information System (INIS)

    Yoneda, Takahiro; Wada, Shigeo; Nakamura, Masanori; Horii, Noriaki; Mizushima, Koichiro

    2011-01-01

    Sound propagation in the lung was simulated for gaining insight into its acoustic properties. A thorax model consisting of lung parenchyma, thoracic bones, trachea and other tissues was made from human CT images. Acoustic nature of the lung parenchyma and bones was expressed with the Biot model of poroelastic material, whereas trachea and tissues were modeled with gas and an elastic material. A point sound source of white noises was placed in the first bifurcation of trachea. The sound propagation in the thorax model was simulated in a frequency domain. The results demonstrated the significant attenuation of sound especially in frequencies larger than 1,000 Hz. Simulations with a stiffened lung demonstrated suppression of the sound attenuation for higher frequencies observed in the normal lung. These results indicate that the normal lung has the nature of a low-pass filter, and stiffening helps the sound at higher frequencies to propagate without attenuations. (author)

  5. Application of semi-supervised deep learning to lung sound analysis.

    Science.gov (United States)

    Chamberlain, Daniel; Kodgule, Rahul; Ganelin, Daniela; Miglani, Vivek; Fletcher, Richard Ribon

    2016-08-01

    The analysis of lung sounds, collected through auscultation, is a fundamental component of pulmonary disease diagnostics for primary care and general patient monitoring for telemedicine. Despite advances in computation and algorithms, the goal of automated lung sound identification and classification has remained elusive. Over the past 40 years, published work in this field has demonstrated only limited success in identifying lung sounds, with most published studies using only a small numbers of patients (typically Ndeep learning algorithm for automatically classify lung sounds from a relatively large number of patients (N=284). Focusing on the two most common lung sounds, wheeze and crackle, we present results from 11,627 sound files recorded from 11 different auscultation locations on these 284 patients with pulmonary disease. 890 of these sound files were labeled to evaluate the model, which is significantly larger than previously published studies. Data was collected with a custom mobile phone application and a low-cost (US$30) electronic stethoscope. On this data set, our algorithm achieves ROC curves with AUCs of 0.86 for wheeze and 0.74 for crackle. Most importantly, this study demonstrates how semi-supervised deep learning can be used with larger data sets without requiring extensive labeling of data.

  6. Sound solutions for habitat monitoring

    Science.gov (United States)

    Mary M. Rowland; Lowell H. Suring; Christina D. Vojta

    2015-01-01

    For agencies and organizations to effectively manage wildlife, knowledge about the status and trend of wildlife habitat is critical. Traditional wildlife monitoring, however, has focused on populations rather than habitat, because ultimately population status drives long-term species viability. Still, habitat loss has contributed to the decline of nearly all at-risk...

  7. Electromagnetic Sampo monitoring soundings at Olkiluoto 2010

    International Nuclear Information System (INIS)

    Korhonen, K.; Korpisalo, A.; Ojamo, H.

    2010-12-01

    The Geological Survey of Finland has carried out electromagnetic frequency-domain depth soundings at fixed measurement stations in Olkiluoto annually since 2004. The purpose of the soundings is to monitor the groundwater conditions in the vicinity of the ONKALO rock characterization facility which will ultimately be part of the final nuclear waste disposal facility for the Finnish nuclear power companies. A new monitoring survey was carried out at the turn of May-June 2010. The survey resulted in 38 successfully performed soundings at 10 stations. The data set spanning the time period of 2004 to 2010 was interpreted with layered-earth models. Most of the interpretations indicate no systematic changes in the level of deep saline groundwater. However, at one station there are indications of a systematic rise in the groundwater level. (orig.)

  8. Analysis of chewing sounds for dietary monitoring

    NARCIS (Netherlands)

    Amft, O.D.; Stäger, M.; Lukowicz, P.; Tröster, G.

    2005-01-01

    The paper reports the results of the first stage of our work on an automatic dietary monitoring system. The work is part of a large European project on using ubiquitous systems to support healthy lifestyle and cardiovascular disease prevention. We demonstrate that sound from the user's mouth can be

  9. Lung sound intensity in patients with emphysema and in normal subjects at standardised airflows

    NARCIS (Netherlands)

    Schreur, H. J.; Sterk, P. J.; Vanderschoot, J.; van Klink, H. C.; van Vollenhoven, E.; Dijkman, J. H.

    1992-01-01

    A common auscultatory finding in pulmonary emphysema is a reduction of lung sounds. This might be due to a reduction in the generation of sounds due to the accompanying airflow limitation or to poor transmission of sounds due to destruction of parenchyma. Lung sound intensity was investigated in

  10. Analysis of adventitious lung sounds originating from pulmonary tuberculosis.

    Science.gov (United States)

    Becker, K W; Scheffer, C; Blanckenberg, M M; Diacon, A H

    2013-01-01

    Tuberculosis is a common and potentially deadly infectious disease, usually affecting the respiratory system and causing the sound properties of symptomatic infected lungs to differ from non-infected lungs. Auscultation is often ruled out as a reliable diagnostic technique for TB due to the random distribution of the infection and the varying severity of damage to the lungs. However, advancements in signal processing techniques for respiratory sounds can improve the potential of auscultation far beyond the capabilities of the conventional mechanical stethoscope. Though computer-based signal analysis of respiratory sounds has produced a significant body of research, there have not been any recent investigations into the computer-aided analysis of lung sounds associated with pulmonary Tuberculosis (TB), despite the severity of the disease in many countries. In this paper, respiratory sounds were recorded from 14 locations around the posterior and anterior chest walls of healthy volunteers and patients infected with pulmonary TB. The most significant signal features in both the time and frequency domains associated with the presence of TB, were identified by using the statistical overlap factor (SOF). These features were then employed to train a neural network to automatically classify the auscultation recordings into their respective healthy or TB-origin categories. The neural network yielded a diagnostic accuracy of 73%, but it is believed that automated filtering of the noise in the clinics, more training samples and perhaps other signal processing methods can improve the results of future studies. This work demonstrates the potential of computer-aided auscultation as an aid for the diagnosis and treatment of TB.

  11. Left–Right Asymmetry in Spectral Characteristics of Lung Sounds Detected Using a Dual-Channel Auscultation System in Healthy Young Adults

    Science.gov (United States)

    Tsai, Jang-Zern; Chang, Ming-Lang; Yang, Jiun-Yue; Kuo, Dar; Lin, Ching-Hsiung; Kuo, Cheng-Deng

    2017-01-01

    Though lung sounds auscultation is important for the diagnosis and monitoring of lung diseases, the spectral characteristics of lung sounds have not been fully understood. This study compared the spectral characteristics of lung sounds between the right and left lungs and between healthy male and female subjects using a dual-channel auscultation system. Forty-two subjects aged 18–22 years without smoking habits and any known pulmonary diseases participated in this study. The lung sounds were recorded from seven pairs of auscultation sites on the chest wall simultaneously. We found that in four out of seven auscultation pairs, the lung sounds from the left lung had a higher total power (PT) than those from the right lung. The PT of male subjects was higher than that of female ones in most auscultation pairs. The ratio of inspiration power to expiration power (RI/E) of lung sounds from the right lung was greater than that from the left lung at auscultation pairs on the anterior chest wall, while this phenomenon was reversed at auscultation pairs on the posterior chest wall in combined subjects, and similarly in both male and female subjects. Though the frequency corresponding to maximum power density of lung sounds (FMPD) from the left and right lungs was not significantly different, the frequency that equally divided the power spectrum of lung sounds (F50) from the left lung was significantly smaller than that from the right lung at auscultation site on the anterior and lateral chest walls, while it was significantly larger than that of from the right lung at auscultation site on the posterior chest walls. In conclusion, significant differences in the PT, FMPD, F50, and RI/E between the left and right lungs at some auscultation pairs were observed by using a dual-channel auscultation system in this study. Structural differences between the left and the right lungs, between the female and male subjects, and between anterior and posterior lungs might account for the

  12. Left–Right Asymmetry in Spectral Characteristics of Lung Sounds Detected Using a Dual-Channel Auscultation System in Healthy Young Adults

    Directory of Open Access Journals (Sweden)

    Jang-Zern Tsai

    2017-06-01

    Full Text Available Though lung sounds auscultation is important for the diagnosis and monitoring of lung diseases, the spectral characteristics of lung sounds have not been fully understood. This study compared the spectral characteristics of lung sounds between the right and left lungs and between healthy male and female subjects using a dual-channel auscultation system. Forty-two subjects aged 18–22 years without smoking habits and any known pulmonary diseases participated in this study. The lung sounds were recorded from seven pairs of auscultation sites on the chest wall simultaneously. We found that in four out of seven auscultation pairs, the lung sounds from the left lung had a higher total power (PT than those from the right lung. The PT of male subjects was higher than that of female ones in most auscultation pairs. The ratio of inspiration power to expiration power (RI/E of lung sounds from the right lung was greater than that from the left lung at auscultation pairs on the anterior chest wall, while this phenomenon was reversed at auscultation pairs on the posterior chest wall in combined subjects, and similarly in both male and female subjects. Though the frequency corresponding to maximum power density of lung sounds (FMPD from the left and right lungs was not significantly different, the frequency that equally divided the power spectrum of lung sounds (F50 from the left lung was significantly smaller than that from the right lung at auscultation site on the anterior and lateral chest walls, while it was significantly larger than that of from the right lung at auscultation site on the posterior chest walls. In conclusion, significant differences in the PT, FMPD, F50, and RI/E between the left and right lungs at some auscultation pairs were observed by using a dual-channel auscultation system in this study. Structural differences between the left and the right lungs, between the female and male subjects, and between anterior and posterior lungs might

  13. Left-Right Asymmetry in Spectral Characteristics of Lung Sounds Detected Using a Dual-Channel Auscultation System in Healthy Young Adults.

    Science.gov (United States)

    Tsai, Jang-Zern; Chang, Ming-Lang; Yang, Jiun-Yue; Kuo, Dar; Lin, Ching-Hsiung; Kuo, Cheng-Deng

    2017-06-07

    Though lung sounds auscultation is important for the diagnosis and monitoring of lung diseases, the spectral characteristics of lung sounds have not been fully understood. This study compared the spectral characteristics of lung sounds between the right and left lungs and between healthy male and female subjects using a dual-channel auscultation system. Forty-two subjects aged 18-22 years without smoking habits and any known pulmonary diseases participated in this study. The lung sounds were recorded from seven pairs of auscultation sites on the chest wall simultaneously. We found that in four out of seven auscultation pairs, the lung sounds from the left lung had a higher total power (P T ) than those from the right lung. The P T of male subjects was higher than that of female ones in most auscultation pairs. The ratio of inspiration power to expiration power (R I/E ) of lung sounds from the right lung was greater than that from the left lung at auscultation pairs on the anterior chest wall, while this phenomenon was reversed at auscultation pairs on the posterior chest wall in combined subjects, and similarly in both male and female subjects. Though the frequency corresponding to maximum power density of lung sounds (F MPD ) from the left and right lungs was not significantly different, the frequency that equally divided the power spectrum of lung sounds (F 50 ) from the left lung was significantly smaller than that from the right lung at auscultation site on the anterior and lateral chest walls, while it was significantly larger than that of from the right lung at auscultation site on the posterior chest walls. In conclusion, significant differences in the P T , F MPD , F 50 , and R I/E between the left and right lungs at some auscultation pairs were observed by using a dual-channel auscultation system in this study. Structural differences between the left and the right lungs, between the female and male subjects, and between anterior and posterior lungs might

  14. Monitoring hydraulic stimulation using telluric sounding

    Science.gov (United States)

    Rees, Nigel; Heinson, Graham; Conway, Dennis

    2018-01-01

    The telluric sounding (TS) method is introduced as a potential tool for monitoring hydraulic fracturing at depth. The advantage of this technique is that it requires only the measurement of electric fields, which are cheap and easy when compared with magnetotelluric measurements. Additionally, the transfer function between electric fields from two locations is essentially the identity matrix for a 1D Earth no matter what the vertical structure. Therefore, changes in the earth resulting from the introduction of conductive bodies underneath one of these sites can be associated with deviations away from the identity matrix, with static shift appearing as a galvanic multiplier at all periods. Singular value decomposition and eigenvalue analysis can reduce the complexity of the resulting telluric distortion matrix to simpler parameters that can be visualised in the form of Mohr circles. This technique would be useful in constraining the lateral extent of resistivity changes. We test the viability of utilising the TS method for monitoring on both a synthetic dataset and for a hydraulic stimulation of an enhanced geothermal system case study conducted in Paralana, South Australia. The synthetic data example shows small but consistent changes in the transfer functions associated with hydraulic stimulation, with grids of Mohr circles introduced as a useful diagnostic tool for visualising the extent of fluid movement. The Paralana electric field data were relatively noisy and affected by the dead band making the analysis of transfer functions difficult. However, changes in the order of 5% were observed from 5 s to longer periods. We conclude that deep monitoring using the TS method is marginal at depths in the order of 4 km and that in order to have meaningful interpretations, electric field data need to be of a high quality with low levels of site noise.[Figure not available: see fulltext.

  15. 21 CFR 868.2450 - Lung water monitor.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 8 2010-04-01 2010-04-01 false Lung water monitor. 868.2450 Section 868.2450 Food... DEVICES ANESTHESIOLOGY DEVICES Monitoring Devices § 868.2450 Lung water monitor. (a) Identification. A lung water monitor is a device used to monitor the trend of fluid volume changes in a patient's lung by...

  16. Lung and Heart Sounds Analysis: State-of-the-Art and Future Trends.

    Science.gov (United States)

    Padilla-Ortiz, Ana L; Ibarra, David

    2018-01-01

    Lung sounds, which include all sounds that are produced during the mechanism of respiration, may be classified into normal breath sounds and adventitious sounds. Normal breath sounds occur when no respiratory problems exist, whereas adventitious lung sounds (wheeze, rhonchi, crackle, etc.) are usually associated with certain pulmonary pathologies. Heart and lung sounds that are heard using a stethoscope are the result of mechanical interactions that indicate operation of cardiac and respiratory systems, respectively. In this article, we review the research conducted during the last six years on lung and heart sounds, instrumentation and data sources (sensors and databases), technological advances, and perspectives in processing and data analysis. Our review suggests that chronic obstructive pulmonary disease (COPD) and asthma are the most common respiratory diseases reported on in the literature; related diseases that are less analyzed include chronic bronchitis, idiopathic pulmonary fibrosis, congestive heart failure, and parenchymal pathology. Some new findings regarding the methodologies associated with advances in the electronic stethoscope have been presented for the auscultatory heart sound signaling process, including analysis and clarification of resulting sounds to create a diagnosis based on a quantifiable medical assessment. The availability of automatic interpretation of high precision of heart and lung sounds opens interesting possibilities for cardiovascular diagnosis as well as potential for intelligent diagnosis of heart and lung diseases.

  17. A Two-Level Sound Classification Platform for Environmental Monitoring

    Directory of Open Access Journals (Sweden)

    Stelios A. Mitilineos

    2018-01-01

    Full Text Available STORM is an ongoing European research project that aims at developing an integrated platform for monitoring, protecting, and managing cultural heritage sites through technical and organizational innovation. Part of the scheduled preventive actions for the protection of cultural heritage is the development of wireless acoustic sensor networks (WASNs that will be used for assessing the impact of human-generated activities as well as for monitoring potentially hazardous environmental phenomena. Collected sound samples will be forwarded to a central server where they will be automatically classified in a hierarchical manner; anthropogenic and environmental activity will be monitored, and stakeholders will be alarmed in the case of potential malevolent behavior or natural phenomena like excess rainfall, fire, gale, high tides, and waves. Herein, we present an integrated platform that includes sound sample denoising using wavelets, feature extraction from sound samples, Gaussian mixture modeling of these features, and a powerful two-layer neural network for automatic classification. We contribute to previous work by extending the proposed classification platform to perform low-level classification too, i.e., classify sounds to further subclasses that include airplane, car, and pistol sounds for the anthropogenic sound class; bird, dog, and snake sounds for the biophysical sound class; and fire, waterfall, and gale for the geophysical sound class. Classification results exhibit outstanding classification accuracy in both high-level and low-level classification thus demonstrating the feasibility of the proposed approach.

  18. Lung sound intensity in patients with emphysema and in normal subjects at standardised airflows.

    Science.gov (United States)

    Schreur, H J; Sterk, P J; Vanderschoot, J; van Klink, H C; van Vollenhoven, E; Dijkman, J H

    1992-01-01

    BACKGROUND: A common auscultatory finding in pulmonary emphysema is a reduction of lung sounds. This might be due to a reduction in the generation of sounds due to the accompanying airflow limitation or to poor transmission of sounds due to destruction of parenchyma. Lung sound intensity was investigated in normal and emphysematous subjects in relation to airflow. METHODS: Eight normal men (45-63 years, FEV1 79-126% predicted) and nine men with severe emphysema (50-70 years, FEV1 14-63% predicted) participated in the study. Emphysema was diagnosed according to pulmonary history, results of lung function tests, and radiographic criteria. All subjects underwent phonopneumography during standardised breathing manoeuvres between 0.5 and 2 1 below total lung capacity with inspiratory and expiratory target airflows of 2 and 1 l/s respectively during 50 seconds. The synchronous measurements included airflow at the mouth and lung volume changes, and lung sounds at four locations on the right chest wall. For each microphone airflow dependent power spectra were computed by using fast Fourier transformation. Lung sound intensity was expressed as log power (in dB) at 200 Hz at inspiratory flow rates of 1 and 2 l/s and at an expiratory flow rate of 1 l/s. RESULTS: Lung sound intensity was well repeatable on two separate days, the intraclass correlation coefficient ranging from 0.77 to 0.94 between the four microphones. The intensity was strongly influenced by microphone location and airflow. There was, however, no significant difference in lung sound intensity at any flow rate between the normal and the emphysema group. CONCLUSION: Airflow standardised lung sound intensity does not differ between normal and emphysematous subjects. This suggests that the auscultatory finding of diminished breath sounds during the regular physical examination in patients with emphysema is due predominantly to airflow limitation. Images PMID:1440459

  19. International perception of lung sounds : a comparison of classification across some European borders

    NARCIS (Netherlands)

    Aviles-Solis, Juan Carlos; Vanbelle, Sophie; Halvorsen, Peder A; Francis, Nick; Cals, Jochen W L; Andreeva, Elena A; Marques, Alda; Piirilä, Päivi; Pasterkamp, Hans; Melbye, Hasse

    2017-01-01

    Introduction: Lung auscultation is helpful in the diagnosis of lung and heart diseases; however, the diagnostic value of lung sounds may be questioned due to interobserver variation. This situation may also impair clinical research in this area to generate evidence-based knowledge about the role

  20. International perception of lung sounds: a comparison of classification across some European borders

    OpenAIRE

    Aviles Solis, Juan Carlos; Vanbelle, Sophie; Halvorsen, Peder Andreas; Francis, Nick; Cals, Jochem W L; Andreeva, Elena A; Marques, Alda; Piirila, Paivi; Pasterkamp, Hans; Melbye, Hasse

    2017-01-01

    Source at http://dx.doi.org/10.1136/bmjresp-2017-000250 Introduction: Lung auscultation is helpful in the diagnosis of lung and heart diseases; however, the diagnostic value of lung sounds may be questioned due to interobserver variation. This situation may also impair clinical research in this area to generate evidence-based knowledge about the role that chest auscultation has in a modern clinical setting. The recording and visual display of lung sounds is a method that is both repeatab...

  1. [Study for lung sound acquisition module based on ARM and Linux].

    Science.gov (United States)

    Lu, Qiang; Li, Wenfeng; Zhang, Xixue; Li, Junmin; Liu, Longqing

    2011-07-01

    A acquisition module with ARM and Linux as a core was developed. This paper presents the hardware configuration and the software design. It is shown that the module can extract human lung sound reliably and effectively.

  2. Developing a reference of normal lung sounds in healthy Peruvian children.

    Science.gov (United States)

    Ellington, Laura E; Emmanouilidou, Dimitra; Elhilali, Mounya; Gilman, Robert H; Tielsch, James M; Chavez, Miguel A; Marin-Concha, Julio; Figueroa, Dante; West, James; Checkley, William

    2014-10-01

    Lung auscultation has long been a standard of care for the diagnosis of respiratory diseases. Recent advances in electronic auscultation and signal processing have yet to find clinical acceptance; however, computerized lung sound analysis may be ideal for pediatric populations in settings, where skilled healthcare providers are commonly unavailable. We described features of normal lung sounds in young children using a novel signal processing approach to lay a foundation for identifying pathologic respiratory sounds. 186 healthy children with normal pulmonary exams and without respiratory complaints were enrolled at a tertiary care hospital in Lima, Peru. Lung sounds were recorded at eight thoracic sites using a digital stethoscope. 151 (81%) of the recordings were eligible for further analysis. Heavy-crying segments were automatically rejected and features extracted from spectral and temporal signal representations contributed to profiling of lung sounds. Mean age, height, and weight among study participants were 2.2 years (SD 1.4), 84.7 cm (SD 13.2), and 12.0 kg (SD 3.6), respectively; and, 47% were boys. We identified ten distinct spectral and spectro-temporal signal parameters and most demonstrated linear relationships with age, height, and weight, while no differences with genders were noted. Older children had a faster decaying spectrum than younger ones. Features like spectral peak width, lower-frequency Mel-frequency cepstral coefficients, and spectro-temporal modulations also showed variations with recording site. Lung sound extracted features varied significantly with child characteristics and lung site. A comparison with adult studies revealed differences in the extracted features for children. While sound-reduction techniques will improve analysis, we offer a novel, reproducible tool for sound analysis in real-world environments.

  3. Developing a Reference of Normal Lung Sounds in Healthy Peruvian Children

    Science.gov (United States)

    Ellington, Laura E.; Emmanouilidou, Dimitra; Elhilali, Mounya; Gilman, Robert H.; Tielsch, James M.; Chavez, Miguel A.; Marin-Concha, Julio; Figueroa, Dante; West, James

    2018-01-01

    Purpose Lung auscultation has long been a standard of care for the diagnosis of respiratory diseases. Recent advances in electronic auscultation and signal processing have yet to find clinical acceptance; however, computerized lung sound analysis may be ideal for pediatric populations in settings, where skilled healthcare providers are commonly unavailable. We described features of normal lung sounds in young children using a novel signal processing approach to lay a foundation for identifying pathologic respiratory sounds. Methods 186 healthy children with normal pulmonary exams and without respiratory complaints were enrolled at a tertiary care hospital in Lima, Peru. Lung sounds were recorded at eight thoracic sites using a digital stethoscope. 151 (81 %) of the recordings were eligible for further analysis. Heavy-crying segments were automatically rejected and features extracted from spectral and temporal signal representations contributed to profiling of lung sounds. Results Mean age, height, and weight among study participants were 2.2 years (SD 1.4), 84.7 cm (SD 13.2), and 12.0 kg (SD 3.6), respectively; and, 47 % were boys. We identified ten distinct spectral and spectro-temporal signal parameters and most demonstrated linear relationships with age, height, and weight, while no differences with genders were noted. Older children had a faster decaying spectrum than younger ones. Features like spectral peak width, lower-frequency Mel-frequency cepstral coefficients, and spectro-temporal modulations also showed variations with recording site. Conclusions Lung sound extracted features varied significantly with child characteristics and lung site. A comparison with adult studies revealed differences in the extracted features for children. While sound-reduction techniques will improve analysis, we offer a novel, reproducible tool for sound analysis in real-world environments. PMID:24943262

  4. Internal-state analysis in layered artificial neural network trained to categorize lung sounds

    NARCIS (Netherlands)

    Oud, M

    2002-01-01

    In regular use of artificial neural networks, only input and output states of the network are known to the user. Weight and bias values can be extracted but are difficult to interpret. We analyzed internal states of networks trained to map asthmatic lung sound spectra onto lung function parameters.

  5. Pollution monitoring of puget sound with honey bees.

    Science.gov (United States)

    Bromenshenk, J J; Carlson, S R; Simpson, J C; Thomas, J M

    1985-02-08

    To show that honey bees are effective biological monitors of environmental contaminants over large geographic areas, beekeepers of Puget Sound, Washington, collected pollen and bees for chemical analysis. From these data, kriging maps of arsenic, cadmium, and fluoride were generated. Results, based on actual concentrations of contaminants in bee tissues, show that the greatest concentrations of contaminants occur close to Commencement Bay and that honey bees are effective as large-scale monitors.

  6. Classification of lung sounds using higher-order statistics: A divide-and-conquer approach.

    Science.gov (United States)

    Naves, Raphael; Barbosa, Bruno H G; Ferreira, Danton D

    2016-06-01

    Lung sound auscultation is one of the most commonly used methods to evaluate respiratory diseases. However, the effectiveness of this method depends on the physician's training. If the physician does not have the proper training, he/she will be unable to distinguish between normal and abnormal sounds generated by the human body. Thus, the aim of this study was to implement a pattern recognition system to classify lung sounds. We used a dataset composed of five types of lung sounds: normal, coarse crackle, fine crackle, monophonic and polyphonic wheezes. We used higher-order statistics (HOS) to extract features (second-, third- and fourth-order cumulants), Genetic Algorithms (GA) and Fisher's Discriminant Ratio (FDR) to reduce dimensionality, and k-Nearest Neighbors and Naive Bayes classifiers to recognize the lung sound events in a tree-based system. We used the cross-validation procedure to analyze the classifiers performance and the Tukey's Honestly Significant Difference criterion to compare the results. Our results showed that the Genetic Algorithms outperformed the Fisher's Discriminant Ratio for feature selection. Moreover, each lung class had a different signature pattern according to their cumulants showing that HOS is a promising feature extraction tool for lung sounds. Besides, the proposed divide-and-conquer approach can accurately classify different types of lung sounds. The classification accuracy obtained by the best tree-based classifier was 98.1% for classification accuracy on training, and 94.6% for validation data. The proposed approach achieved good results even using only one feature extraction tool (higher-order statistics). Additionally, the implementation of the proposed classifier in an embedded system is feasible. Copyright © 2016 Elsevier Ireland Ltd. All rights reserved.

  7. Using K-Nearest Neighbor Classification to Diagnose Abnormal Lung Sounds

    Directory of Open Access Journals (Sweden)

    Chin-Hsing Chen

    2015-06-01

    Full Text Available A reported 30% of people worldwide have abnormal lung sounds, including crackles, rhonchi, and wheezes. To date, the traditional stethoscope remains the most popular tool used by physicians to diagnose such abnormal lung sounds, however, many problems arise with the use of a stethoscope, including the effects of environmental noise, the inability to record and store lung sounds for follow-up or tracking, and the physician’s subjective diagnostic experience. This study has developed a digital stethoscope to help physicians overcome these problems when diagnosing abnormal lung sounds. In this digital system, mel-frequency cepstral coefficients (MFCCs were used to extract the features of lung sounds, and then the K-means algorithm was used for feature clustering, to reduce the amount of data for computation. Finally, the K-nearest neighbor method was used to classify the lung sounds. The proposed system can also be used for home care: if the percentage of abnormal lung sound frames is > 30% of the whole test signal, the system can automatically warn the user to visit a physician for diagnosis. We also used bend sensors together with an amplification circuit, Bluetooth, and a microcontroller to implement a respiration detector. The respiratory signal extracted by the bend sensors can be transmitted to the computer via Bluetooth to calculate the respiratory cycle, for real-time assessment. If an abnormal status is detected, the device will warn the user automatically. Experimental results indicated that the error in respiratory cycles between measured and actual values was only 6.8%, illustrating the potential of our detector for home care applications.

  8. Sound at the zoo: Using animal monitoring, sound measurement, and noise reduction in zoo animal management.

    Science.gov (United States)

    Orban, David A; Soltis, Joseph; Perkins, Lori; Mellen, Jill D

    2017-05-01

    A clear need for evidence-based animal management in zoos and aquariums has been expressed by industry leaders. Here, we show how individual animal welfare monitoring can be combined with measurement of environmental conditions to inform science-based animal management decisions. Over the last several years, Disney's Animal Kingdom® has been undergoing significant construction and exhibit renovation, warranting institution-wide animal welfare monitoring. Animal care and science staff developed a model that tracked animal keepers' daily assessments of an animal's physical health, behavior, and responses to husbandry activity; these data were matched to different external stimuli and environmental conditions, including sound levels. A case study of a female giant anteater and her environment is presented to illustrate how this process worked. Associated with this case, several sound-reducing barriers were tested for efficacy in mitigating sound. Integrating daily animal welfare assessment with environmental monitoring can lead to a better understanding of animals and their sensory environment and positively impact animal welfare. © 2017 Wiley Periodicals, Inc.

  9. A comprehensive computational model of sound transmission through the porcine lung.

    Science.gov (United States)

    Dai, Zoujun; Peng, Ying; Henry, Brian M; Mansy, Hansen A; Sandler, Richard H; Royston, Thomas J

    2014-09-01

    A comprehensive computational simulation model of sound transmission through the porcine lung is introduced and experimentally evaluated. This "subject-specific" model utilizes parenchymal and major airway geometry derived from x-ray CT images. The lung parenchyma is modeled as a poroviscoelastic material using Biot theory. A finite element (FE) mesh of the lung that includes airway detail is created and used in comsol FE software to simulate the vibroacoustic response of the lung to sound input at the trachea. The FE simulation model is validated by comparing simulation results to experimental measurements using scanning laser Doppler vibrometry on the surface of an excised, preserved lung. The FE model can also be used to calculate and visualize vibroacoustic pressure and motion inside the lung and its airways caused by the acoustic input. The effect of diffuse lung fibrosis and of a local tumor on the lung acoustic response is simulated and visualized using the FE model. In the future, this type of visualization can be compared and matched with experimentally obtained elastographic images to better quantify regional lung material properties to noninvasively diagnose and stage disease and response to treatment.

  10. Measurement and classification of heart and lung sounds by using LabView for educational use.

    Science.gov (United States)

    Altrabsheh, B

    2010-01-01

    This study presents the design, development and implementation of a simple low-cost method of phonocardiography signal detection. Human heart and lung signals are detected by using a simple microphone through a personal computer; the signals are recorded and analysed using LabView software. Amplitude and frequency analyses are carried out for various phonocardiography pathological cases. Methods for automatic classification of normal and abnormal heart sounds, murmurs and lung sounds are presented. Various cases of heart and lung sound measurement are recorded and analysed. The measurements can be saved for further analysis. The method in this study can be used by doctors as a detection tool aid and may be useful for teaching purposes at medical and nursing schools.

  11. Interpretation of electromagnetic Sampo monitoring soundings of Olkiluoto

    International Nuclear Information System (INIS)

    Korhonen, K.

    2010-04-01

    The Geological Survey of Finland (GTK) has carried out electromagnetic Sampo soundings at Olkiluoto annually since 2004 commissioned by Posiva. The soundings have been carried out at the same measurement stations every year. The goal of the soundings is to detect any changes in the electrical conditions of the bedrock surrounding the ONKALO underground research facility. This study aims to detect possible changes in the groundwater conditions using modelling. The sensitivity of the Sampo method to changes in the electrical properties and the level of groundwater were investigated as part of this study. The results of the sensitivity investigation indicate that the Sampo method is capable of detecting changes occurring even quite deep in the bedrock. Thus, the usage of the Sampo method to monitor the groundwater conditions is warranted. The plots of apparent resistivity as a function of depth indicate that the area directly above the ONKALO facility is very disturbed electromagnetically. However, most of the soundings to the east and west of ONKALO are of better quality and were interpreted. The results indicate possible changes in the groundwater conditions. The level of saline groundwater may be sinking in the eastern part while it may be rising on the western part. (orig.)

  12. International perception of lung sounds: a comparison of classification across some European borders.

    Science.gov (United States)

    Aviles-Solis, Juan Carlos; Vanbelle, Sophie; Halvorsen, Peder A; Francis, Nick; Cals, Jochen W L; Andreeva, Elena A; Marques, Alda; Piirilä, Päivi; Pasterkamp, Hans; Melbye, Hasse

    2017-01-01

    Lung auscultation is helpful in the diagnosis of lung and heart diseases; however, the diagnostic value of lung sounds may be questioned due to interobserver variation. This situation may also impair clinical research in this area to generate evidence-based knowledge about the role that chest auscultation has in a modern clinical setting. The recording and visual display of lung sounds is a method that is both repeatable and feasible to use in large samples, and the aim of this study was to evaluate interobserver agreement using this method. With a microphone in a stethoscope tube, we collected digital recordings of lung sounds from six sites on the chest surface in 20 subjects aged 40 years or older with and without lung and heart diseases. A total of 120 recordings and their spectrograms were independently classified by 28 observers from seven different countries. We employed absolute agreement and kappa coefficients to explore interobserver agreement in classifying crackles and wheezes within and between subgroups of four observers. When evaluating agreement on crackles (inspiratory or expiratory) in each subgroup, observers agreed on between 65% and 87% of the cases. Conger's kappa ranged from 0.20 to 0.58 and four out of seven groups reached a kappa of ≥0.49. In the classification of wheezes, we observed a probability of agreement between 69% and 99.6% and kappa values from 0.09 to 0.97. Four out of seven groups reached a kappa ≥0.62. The kappa values we observed in our study ranged widely but, when addressing its limitations, we find the method of recording and presenting lung sounds with spectrograms sufficient for both clinic and research. Standardisation of terminology across countries would improve international communication on lung auscultation findings.

  13. The effect of methacholine-induced acute airway narrowing on lung sounds in normal and asthmatic subjects

    NARCIS (Netherlands)

    Schreur, H. J.; Vanderschoot, J.; Zwinderman, A. H.; Dijkman, J. H.; Sterk, P. J.

    1995-01-01

    The association between lung sound alterations and airways obstruction has long been recognized in clinical practice, but the precise pathophysiological mechanisms of this relationship have not been determined. Therefore, we examined the changes in lung sounds at well-defined levels of

  14. Electromagnetic SAMPO monitoring soundings at Olkiluoto 2011 with updated interpretations

    International Nuclear Information System (INIS)

    Korhonen, K.

    2013-11-01

    The Geological Survey of Finland (GTK) has carried out electromagnetic depth soundings annually at fixed stations in Olkiluoto since 2004 as part of a monitoring programme. The goal of the programme is to detect and monitor changes in the electrical properties of the bedrock above and in the vicinity of the underground nuclear waste disposal facility. A new Sampo monitoring survey was carried out during September-October 2011. The survey resulted in 39 soundings at 17 measurement stations. The nominal coil separations of 200, 400, 500, 600 and 800 meters were used. Eight stations were selected for detailed annual layer-model interpretation. The layer models were based on prior geological and geophysical knowledge of the area. The thicknesses of the layer-model layers were kept fixed whereas their resistivities were solved for each subsequent year independent of each other. Many time series indicate clear trends in electrical resistivity. However, even though the data was carefully corrected and edited, the time series display a fairly large amount of variability increasing the uncertainty of the calculated trends. (orig.)

  15. Application of Clustering Techniques for Lung Sounds to Improve Interpretability and Detection of Crackles

    Directory of Open Access Journals (Sweden)

    Germán D. Sosa

    2015-01-01

    Full Text Available Due to the subjectivity involved currently in pulmonary auscultation process and its diagnostic to evaluate the condition of respiratory airways, this work pretends to evaluate the performance of clustering algorithms such as k-means and DBSCAN to perform a computational analysis of lung sounds aiming to visualize a representation of such sounds that highlights the presence of crackles and the energy associated with them. In order to achieve that goal, Wavelet analysis techniques were used in contrast to traditional frequency analysis given the similarity between the typical waveform for a crackle and the wavelet sym4. Once the lung sound signal with isolated crackles is obtained, the clustering process groups crackles in regions of high density and provides visualization that might be useful for the diagnostic made by an expert. Evaluation suggests that k-means groups crackle more effective than DBSCAN in terms of generated clusters.

  16. Lung sound analysis helps localize airway inflammation in patients with bronchial asthma

    Directory of Open Access Journals (Sweden)

    Shimoda T

    2017-03-01

    Full Text Available Terufumi Shimoda,1 Yasushi Obase,2 Yukio Nagasaka,3 Hiroshi Nakano,1 Akiko Ishimatsu,1 Reiko Kishikawa,1 Tomoaki Iwanaga1 1Clinical Research Center, Fukuoka National Hospital, Fukuoka, 2Second Department of Internal Medicine, School of Medicine, Nagasaki University, Nagasaki, 3Kyoto Respiratory Center, Otowa Hospital, Kyoto, Japan Purpose: Airway inflammation can be detected by lung sound analysis (LSA at a single point in the posterior lower lung field. We performed LSA at 7 points to examine whether the technique could identify the location of airway inflammation in patients with asthma. Patients and methods: Breath sounds were recorded at 7 points on the body surface of 22 asthmatic subjects. Inspiration sound pressure level (ISPL, expiration sound pressure level (ESPL, and the expiration-to-inspiration sound pressure ratio (E/I were calculated in 6 frequency bands. The data were analyzed for potential correlation with spirometry, airway hyperresponsiveness (PC20, and fractional exhaled nitric oxide (FeNO. Results: The E/I data in the frequency range of 100–400 Hz (E/I low frequency [LF], E/I mid frequency [MF] were better correlated with the spirometry, PC20, and FeNO values than were the ISPL or ESPL data. The left anterior chest and left posterior lower recording positions were associated with the best correlations (forced expiratory volume in 1 second/forced vital capacity: r=–0.55 and r=–0.58; logPC20: r=–0.46 and r=–0.45; and FeNO: r=0.42 and r=0.46, respectively. The majority of asthmatic subjects with FeNO ≥70 ppb exhibited high E/I MF levels in all lung fields (excluding the trachea and V50%pred <80%, suggesting inflammation throughout the airway. Asthmatic subjects with FeNO <70 ppb showed high or low E/I MF levels depending on the recording position, indicating uneven airway inflammation. Conclusion: E/I LF and E/I MF are more useful LSA parameters for evaluating airway inflammation in bronchial asthma; 7-point lung

  17. Water quality monitoring and data collection in the Mississippi sound

    Science.gov (United States)

    Runner, Michael S.; Creswell, R.

    2002-01-01

    The United States Geological Survey and the Mississippi Department of Marine Resources are collecting data on the quality of the water in the Mississippi Sound of the Gulf of Mexico, and streamflow data for its tributaries. The U.S. Geological Survey is collecting continuous water-level data, continuous and discrete water-temperature data, continuous and discrete specific-conductance data, as well as chloride and salinity samples at two locations in the Mississippi Sound and three Corps of Engineers tidal gages. Continuous-discharge data are also being collected at two additional stations on tributaries. The Mississippi Department of Marine Resources collects water samples at 169 locations in the Gulf of Mexico. Between 1800 and 2000 samples are collected annually which are analyzed for turbidity and fecal coliform bacteria. The continuous data are made available real-time through the internet and are being used in conjunction with streamflow data, weather data, and sampling data for the monitoring and management of the oyster reefs, the shrimp fishery and other marine species and their habitats.

  18. Sound

    CERN Document Server

    Robertson, William C

    2003-01-01

    Muddled about what makes music? Stuck on the study of harmonics? Dumbfounded by how sound gets around? Now you no longer have to struggle to teach concepts you really don t grasp yourself. Sound takes an intentionally light touch to help out all those adults science teachers, parents wanting to help with homework, home-schoolers seeking necessary scientific background to teach middle school physics with confidence. The book introduces sound waves and uses that model to explain sound-related occurrences. Starting with the basics of what causes sound and how it travels, you'll learn how musical instruments work, how sound waves add and subtract, how the human ear works, and even why you can sound like a Munchkin when you inhale helium. Sound is the fourth book in the award-winning Stop Faking It! Series, published by NSTA Press. Like the other popular volumes, it is written by irreverent educator Bill Robertson, who offers this Sound recommendation: One of the coolest activities is whacking a spinning metal rod...

  19. Puget Sound Intertidal Habitat Inventory; Puget Sound Ambient Monitoring Program, 1996 (NODC Accession 9900221)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Puget Sound's intertidal areas provide habitat for species of commercial, recreational, biotic, and aesthetic value. Habitat is a critical ecosystem component -- it...

  20. Measurement of sound velocity profiles in fluids for process monitoring

    International Nuclear Information System (INIS)

    Wolf, M; Kühnicke, E; Lenz, M; Bock, M

    2012-01-01

    In ultrasonic measurements, the time of flight to the object interface is often the only information that is analysed. Conventionally it is only possible to determine distances or sound velocities if the other value is known. The current paper deals with a novel method to measure the sound propagation path length and the sound velocity in media with moving scattering particles simultaneously. Since the focal position also depends on sound velocity, it can be used as a second parameter. Via calibration curves it is possible to determine the focal position and sound velocity from the measured time of flight to the focus, which is correlated to the maximum of averaged echo signal amplitude. To move focal position along the acoustic axis, an annular array is used. This allows measuring sound velocity locally resolved without any previous knowledge of the acoustic media and without a reference reflector. In previous publications the functional efficiency of this method was shown for media with constant velocities. In this work the accuracy of these measurements is improved. Furthermore first measurements and simulations are introduced for non-homogeneous media. Therefore an experimental set-up was created to generate a linear temperature gradient, which also causes a gradient of sound velocity.

  1. Design of Wearable Breathing Sound Monitoring System for Real-Time Wheeze Detection

    Directory of Open Access Journals (Sweden)

    Shih-Hong Li

    2017-01-01

    Full Text Available In the clinic, the wheezing sound is usually considered as an indicator symptom to reflect the degree of airway obstruction. The auscultation approach is the most common way to diagnose wheezing sounds, but it subjectively depends on the experience of the physician. Several previous studies attempted to extract the features of breathing sounds to detect wheezing sounds automatically. However, there is still a lack of suitable monitoring systems for real-time wheeze detection in daily life. In this study, a wearable and wireless breathing sound monitoring system for real-time wheeze detection was proposed. Moreover, a breathing sounds analysis algorithm was designed to continuously extract and analyze the features of breathing sounds to provide the objectively quantitative information of breathing sounds to professional physicians. Here, normalized spectral integration (NSI was also designed and applied in wheeze detection. The proposed algorithm required only short-term data of breathing sounds and lower computational complexity to perform real-time wheeze detection, and is suitable to be implemented in a commercial portable device, which contains relatively low computing power and memory. From the experimental results, the proposed system could provide good performance on wheeze detection exactly and might be a useful assisting tool for analysis of breathing sounds in clinical diagnosis.

  2. Monitoring of aquifer pump tests with Magnetic Resonance Sounding (MRS)

    DEFF Research Database (Denmark)

    Herckenrath, Daan; Auken, Esben; Bauer-Gottwein, Peter

    2009-01-01

    Magnetic Resonance Sounding (MRS) can provide valuable data to constrain and calibrate groundwater flow and transport models. With this non-invasive geophysical technique, field measurements of water content and hydraulic conductivities can be obtained. We developed a hydrogeophyiscal forward...

  3. Lung Injury; Relates to Real-Time Endoscopic Monitoring of Single Cells Respiratory Health in Lung

    Science.gov (United States)

    2017-09-01

    AWARD NUMBER: W81XWH-16-1-0253 TITLE: Lung Injury; Relates to Real- Time Endoscopic Monitoring of Single Cells Respiratory Health in Lung...2017 TYPE OF REPORT: Annual PREPARED FOR: U.S. Army Medical Research and Materiel Command Fort Detrick, Maryland 21702-5012 DISTRIBUTION ...STATEMENT: Approved for Public Release; Distribution Unlimited The views, opinions and/or findings contained in this report are those of the author(s

  4. Harmful Algal Bloom Monitoring Data for Puget Sound - SoundToxins: Partnership for Enhanced Monitoring and Emergency Response to Harmful Algal Blooms in Puget Sound

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Toxic outbreaks of species of the dinoflagellate Alexandrium have become pervasive in the Puget Sound region over the last two decades, escalating the threats to...

  5. Usability of Computerized Lung Auscultation-Sound Software (CLASS) for learning pulmonary auscultation.

    Science.gov (United States)

    Machado, Ana; Oliveira, Ana; Jácome, Cristina; Pereira, Marco; Moreira, José; Rodrigues, João; Aparício, José; Jesus, Luis M T; Marques, Alda

    2018-04-01

    The mastering of pulmonary auscultation requires complex acoustic skills. Computer-assisted learning tools (CALTs) have potential to enhance the learning of these skills; however, few have been developed for this purpose and do not integrate all the required features. Thus, this study aimed to assess the usability of a new CALT for learning pulmonary auscultation. Computerized Lung Auscultation-Sound Software (CLASS) usability was assessed by eight physiotherapy students using computer screen recordings, think-aloud reports, and facial expressions. Time spent in each task, frequency of messages and facial expressions, number of clicks and problems reported were counted. The timelines of the three methods used were matched/synchronized and analyzed. The tasks exercises and annotation of respiratory sounds were the ones requiring more clicks (median 132, interquartile range [23-157]; 93 [53-155]; 91 [65-104], respectively) and where most errors (19; 37; 15%, respectively) and problems (n = 7; 6; 3, respectively) were reported. Each participant reported a median of 6 problems, with a total of 14 different problems found, mainly related with CLASS functionalities (50%). Smile was the only facial expression presented in all tasks (n = 54). CLASS is the only CALT available that meets all the required features for learning pulmonary auscultation. The combination of the three usability methods identified advantages/disadvantages of CLASS and offered guidance for future developments, namely in annotations and exercises. This will allow the improvement of CLASS and enhance students' activities for learning pulmonary auscultation skills.

  6. Usefulness of the second heart sound for predicting pulmonary hypertension in patients with interstitial lung disease

    Directory of Open Access Journals (Sweden)

    Sandra de Barros Cobra

    Full Text Available CONTEXT AND OBJECTIVE: P2 hyperphonesis is considered to be a valuable finding in semiological diagnoses of pulmonary hypertension (PH. The aim here was to evaluate the accuracy of the pulmonary component of second heart sounds for predicting PH in patients with interstitial lung disease. DESIGN AND SETTING: Cross-sectional study at the University of Brasilia and Hospital de Base do Distrito Federal. METHODS: Heart sounds were acquired using an electronic stethoscope and were analyzed using phonocardiography. Clinical signs suggestive of PH, such as second heart sound (S2 in pulmonary area louder than in aortic area; P2 > A2 in pulmonary area and P2 present in mitral area, were compared with Doppler echocardiographic parameters suggestive of PH. Sensitivity (S, specificity (Sp and positive (LR+ and negative (LR- likelihood ratios were evaluated. RESULTS: There was no significant correlation between S2 or P2 amplitude and PASP (pulmonary artery systolic pressure (P = 0.185 and 0.115; P= 0.13 and 0.34, respectively. Higher S2 in pulmonary area than in aortic area, compared with all the criteria suggestive of PH, showed S = 60%, Sp= 22%; LR+ = 0.7; LR- = 1.7; while P2> A2 showed S= 57%, Sp = 39%; LR+ = 0.9; LR- = 1.1; and P2 in mitral area showed: S= 68%, Sp = 41%; LR+ = 1.1; LR- = 0.7. All these signals together showed: S= 50%, Sp = 56%. CONCLUSIONS: The semiological signs indicative of PH presented low sensitivity and specificity levels for clinically diagnosing this comorbidity.

  7. Assessing and optimizing infra-sound networks to monitor volcanic eruptions

    International Nuclear Information System (INIS)

    Tailpied, Dorianne

    2016-01-01

    Understanding infra-sound signals is essential to monitor compliance with the Comprehensive Nuclear-Test ban Treaty, and also to demonstrate the potential of the global monitoring infra-sound network for civil and scientific applications. The main objective of this thesis is to develop a robust tool to estimate and optimize the performance of any infra-sound network to monitor explosive sources such as volcanic eruptions. Unlike previous studies, the developed method has the advantage to consider realistic atmospheric specifications along the propagation path, source frequency and noise levels at the stations. It allows to predict the attenuation and the minimum detectable source amplitude. By simulating the performances of any infra-sound networks, it is then possible to define the optimal configuration of the network to monitor a specific region, during a given period. When carefully adding a station to the existing network, performance can be improved by a factor of 2. However, it is not always possible to complete the network. A good knowledge of detection capabilities at large distances is thus essential. To provide a more realistic picture of the performance, we integrate the atmospheric longitudinal variability along the infra-sound propagation path in our simulations. This thesis also contributes in providing a confidence index taking into account the uncertainties related to propagation and atmospheric models. At high frequencies, the error can reach 40 dB. Volcanic eruptions are natural, powerful and valuable calibrating sources of infra-sound, worldwide detected. In this study, the well instrumented volcanoes Yasur, in Vanuatu, and Etna, in Italy, offer a unique opportunity to validate our attenuation model. In particular, accurate comparisons between near-field recordings and far-field detections of these volcanoes have helped to highlight the potential of our simulation tool to remotely monitor volcanoes. Such work could significantly help to prevent

  8. Albemarle Sound demonstration study of the national monitoring network for US coastal waters and their tributaries

    Science.gov (United States)

    Michelle Moorman; Sharon Fitzgerald; Keith Loftin; Elizabeth Fensin

    2016-01-01

    The U.S. Geological Survey’s (USGS) is implementing a demonstration project in the Albemarle Sound for the National Monitoring Network for U.S. coastal waters and their tributaries. The goal of the National Monitoring Network is to provide information about the health of our oceans and coastal ecosystems and inland influences on coastal waters for improved resource...

  9. Estuarine monitoring programs in the Albemarle Sound study area, North Carolina

    Science.gov (United States)

    Moorman, Michelle; Kolb, Katharine R.; Supak, Stacy

    2014-01-01

    Albemarle Sound was selected in 2012 as one of the two demonstration sites in the Nation to test and improve the design of the National Water Quality Monitoring Council’s National Monitoring Network (NMN) for U.S. Coastal Waters and their tributaries. The goal of the NMN for U.S. coastal waters and tributaries is to provide information about the health of our oceans and coastal ecosystems and inland influences on coastal waters for improved resource management. The NMN is an integrated, multidisciplinary, and multiorganizational program using multiple sources of data and information to augment current monitoring programs.

  10. Elecromagnetic Sampo monitoring soundings at Olkiluoto in 2013 with updated interpretations

    International Nuclear Information System (INIS)

    Korhonen, K.

    2014-10-01

    The Geological Survey of Finland (GTK) has carried out electromagnetic depth soundings annually at fixed stations in Olkiluoto since 2004 as part of a monitoring program. The goal of the monitoring program is to detect and monitor changes in the electrical properties of the bedrock in the vicinity of the ONKALO underground research facility which will constitute a part of the final nuclear waste repository. A new Sampo monitoring survey was carried out by GTK in October 2013. The survey consists of 37 soundings performed at 17 measurement stations. The nominal coil separations of 200, 400, 500, 600 and 800 metres were used depending on the station. Layer-model interpretations of soundings at eight selected stations were updated with the new data. The interpretations indicate consistent annual changes. Resistivities be-low stations to the East of the ONKALO facility appear to increase annually. In contrast, resistivities below stations to the West of the ONKALO facility appear to decrease annually. However, these changes need to be considered keeping in mind the uncertainties associated with the data and their interpretations. (orig.)

  11. Monitoring of surface chemical and underground nuclear explosions with help of ionospheric radio-sounding above test site

    International Nuclear Information System (INIS)

    Krasnov, V.M.; Drobzheva, Ya.V.

    2000-01-01

    We describe the basic principles, advantages and disadvantages of ionospheric method to monitor surface chemical and underground nuclear explosions. The ionosphere is 'an apparatus' for the infra-sound measurements immediately above the test site. Using remote radio sounding of the ionosphere you can obtain that information. So you carry out the inspection at the test site. The main disadvantage of the ionospheric method is the necessity to sound the ionosphere with radio waves. (author)

  12. Lung function interpolation by analysis of means of neural-network-supported respiration sounds

    NARCIS (Netherlands)

    Oud, M

    Respiration sounds of individual asthmatic patients were analysed in the scope of the development of a method for computerised recognition of the degree of airways obstruction. Respiration sounds were recorded during laboratory sessions of allergen provoked airways obstruction, during several stages

  13. Assays for predicting and monitoring responses to lung cancer immunotherapy

    International Nuclear Information System (INIS)

    Teixidó, Cristina; Karachaliou, Niki; González-Cao, Maria; Morales-Espinosa, Daniela; Rosell, Rafael

    2015-01-01

    Immunotherapy has become a key strategy for cancer treatment, and two immune checkpoints, namely, programmed cell death 1 (PD-1) and its ligand (PD-L1), have recently emerged as important targets. The interaction blockade of PD-1 and PD-L1 demonstrated promising activity and antitumor efficacy in early phase clinical trials for advanced solid tumors such as non-small cell lung cancer (NSCLC). Many cell types in multiple tissues express PD-L1 as well as several tumor types, thereby suggesting that the ligand may play important roles in inhibiting immune responses throughout the body. Therefore, PD-L1 is a critical immunomodulating component within the lung microenvironment, but the correlation between PD-L1 expression and prognosis is controversial. More evidence is required to support the use of PD-L1 as a potential predictive biomarker. Clinical trials have measured PD-L1 in tumor tissues by immunohistochemistry (IHC) with different antibodies, but the assessment of PD-L1 is not yet standardized. Some commercial antibodies lack specificity and their reproducibility has not been fully evaluated. Further studies are required to clarify the optimal IHC assay as well as to predict and monitor the immune responses of the PD-1/PD-L1 pathway

  14. Feasibility of an electronic stethoscope system for monitoring neonatal bowel sounds.

    Science.gov (United States)

    Dumas, Jasmine; Hill, Krista M; Adrezin, Ronald S; Alba, Jorge; Curry, Raquel; Campagna, Eric; Fernandes, Cecilia; Lamba, Vineet; Eisenfeld, Leonard

    2013-09-01

    Bowel dysfunction remains a major problem in neonates. Traditional auscultation of bowel sounds as a diagnostic aid in neonatal gastrointestinal complications is limited by skill and inability to document and reassess. Consequently, we built a unique prototype to investigate the feasibility of an electronic monitoring system for continuous assessment of bowel sounds. We attained approval by the Institutional Review Boards for the investigational study to test our system. The system incorporated a prototype stethoscope head with a built-in microphone connected to a digital recorder. Recordings made over extended periods were evaluated for quality. We also considered the acoustic environment of the hospital, where the stethoscope was used. The stethoscope head was attached to the abdomen with a hydrogel patch designed especially for this purpose. We used the system to obtain recordings from eight healthy, full-term babies. A scoring system was used to determine loudness, clarity, and ease of recognition comparing it to the traditional stethoscope. The recording duration was initially two hours and was increased to a maximum of eight hours. Median duration of attachment was three hours (3.75, 2.68). Based on the scoring, the bowel sound recording was perceived to be as loud and clear in sound reproduction as a traditional stethoscope. We determined that room noise and other noises were significant forms of interference in the recordings, which at times prevented analysis. However, no sound quality drift was noted in the recordings and no patient discomfort was noted. Minimal erythema was observed over the fixation site which subsided within one hour. We demonstrated the long-term recording of infant bowel sounds. Our contributions included a prototype stethoscope head, which was affixed using a specially designed hydrogel adhesive patch. Such a recording can be reviewed and reassessed, which is new technology and an improvement over current practice. The use of this

  15. Monitoring sound to quantify snoring and sleep apnea severity using a smartphone: proof of concept.

    Science.gov (United States)

    Nakano, Hiroshi; Hirayama, Kenji; Sadamitsu, Yumiko; Toshimitsu, Ayaka; Fujita, Hisayuki; Shin, Shizue; Tanigawa, Takeshi

    2014-01-15

    Habitual snoring is a prevalent condition that is not only a marker of obstructive sleep apnea (OSA) but can also lead to vascular risk. However, it is not easy to check snoring status at home. We attempted to develop a snoring sound monitor consisting of a smartphone alone, which is aimed to quantify snoring and OSA severity. The subjects included 50 patients who underwent diagnostic polysomnography (PSG), of which the data of 10 patients were used for developing the program and that of 40 patients were used for validating the program. A smartphone was attached to the anterior chest wall over the sternum. It acquired ambient sound from the built-in microphone and analyzed it using a fast Fourier transform on a real-time basis. Snoring time measured by the smartphone highly correlated with snoring time measured by PSG (r = 0.93). The top 1 percentile value of sound pressure level (L1) determined by the smartphone correlated with the ambient sound L1 during sleep determined by PSG (r = 0.92). Moreover, the respiratory disturbance index estimated by the smartphone (smart-RDI) highly correlated with the apnea-hypopnea index (AHI) obtained by PSG (r = 0.94). The diagnostic sensitivity and specificity of the smart-RDI for diagnosing OSA (AHI ≥ 15) were 0.70 and 0.94, respectively. A smartphone can be used for effectively monitoring snoring and OSA in a controlled laboratory setting. Use of this technology in a noisy home environment remains unproven, and further investigation is needed.

  16. Electromagnetic SAMPO monitoring soundings at OLKILUOTO in 2012 with updated interpretations

    International Nuclear Information System (INIS)

    Korhonen, K.

    2013-11-01

    The Geological Survey of Finland (GTK) has carried out electromagnetic depth soundings annually at fixed stations at Olkiluoto since 2004 as part of a monitoring programme. The goal of the programme is to detect and monitor changes in the electrical properties of the bedrock above and in the vicinity of the ONKALO tunnel which will serve as a part of the future underground nuclear waste disposal facility. A new Sampo monitoring survey was carried out during October 2012. The survey plan of 2011 was slightly modified and 36 soundings at 16 measurement stations were carried out. The nominal coil separations of 200, 400, 500, 600 and 800 meters were used. Interpretations at eight selected stations were updated with the new data. The interpretations indicate consistent statistically significant changes. Annual increases in resistivity were detected at stations to the East of ONKALO while annual decreases in resistivity were detected to the West of ONKALO. However, these changes need to be considered keeping in mind the high degree of uncertainty associated with the data and their interpretations. (orig.)

  17. Weight preserving image registration for monitoring disease progression in lung CT

    DEFF Research Database (Denmark)

    Gorbunova, Vladlena; Lo, Pechin Chien Pau; Haseem, Ashraf

    2008-01-01

    We present a new image registration based method for monitoring regional disease progression in longitudinal image studies of lung disease. A free-form image registration technique is used to match a baseline 3D CT lung scan onto a following scan. Areas with lower intensity in the following scan...... the density of lung tissue with respect to local expansion or compression such that the total weight of the lungs is preserved during deformation. Our method provides a good estimation of regional destruction of lung tissue for subjects with a significant difference in inspiration level between CT scans...

  18. Using quantitative breath sound measurements to predict lung function following resection

    Directory of Open Access Journals (Sweden)

    Keus Leendert

    2010-10-01

    Full Text Available Abstract Background Predicting postoperative lung function is important for estimating the risk of complications and long-term disability after pulmonary resection. We investigated the capability of vibration response imaging (VRI as an alternative to lung scintigraphy for prediction of postoperative lung function in patients with intrathoracic malignancies. Methods Eighty-five patients with intrathoracic malignancies, considered candidates for lung resection, were prospectively studied. The projected postoperative (ppo lung function was calculated using: perfusion scintigraphy, ventilation scintigraphy, and VRI. Two sets of assessments made: one for lobectomy and one for pneumonectomy. Clinical concordance was defined as both methods agreeing that either a patient was or was not a surgical candidate based on a ppoFEV1% and ppoDLCO% > 40%. Results Limits of agreement between scintigraphy and VRI for ppo following lobectomy were -16.47% to 15.08% (mean difference = -0.70%;95%CI = -2.51% to 1.12% and for pneumonectomy were -23.79% to 19.04% (mean difference = -2.38%;95%CI = -4.69% to -0.07%. Clinical concordance between VRI and scintigraphy was 73% for pneumonectomy and 98% for lobectomy. For patients who had surgery and postoperative lung function testing (n = 31, ppoFEV1% using scintigraphic methods correlated with measured postoperative values better than projections using VRI, (adjusted R2 = 0.32 scintigraphy; 0.20 VRI, however the difference between methods failed to reach statistical significance. Limits of agreement between measured FEV1% postoperatively and ppoFEV1% based on perfusion scintigraphy were -16.86% to 23.73% (mean difference = 3.44%;95%CI = -0.29% to 7.16%; based on VRI were -19.56% to 28.99% (mean difference = 4.72%;95%CI = 0.27% to 9.17%. Conclusions Further investigation of VRI as an alternative to lung scintigraphy for prediction of postoperative lung function is warranted.

  19. SoundProof: A Smartphone Platform for Wireless Monitoring of Wildlife and Environment

    Science.gov (United States)

    Lukac, M.; Monibi, M.; Lane, M. L.; Howell, L.; Ramanathan, N.; Borker, A.; McKown, M.; Croll, D.; Terschy, B.

    2011-12-01

    We are developing an open-source, low-cost wildlife and environmental monitoring solution based on Android smartphones. Using a smartphone instead of a traditional microcontroller or single board computer has several advantages: smartphones are single integrated devices with multiple radios and a battery; they have a robust software interface which enables customization; and are field-tested by millions of users daily. Consequently, smartphones can improve the cost, configurability, and real-time access to data for environmental monitoring, ultimately replacing existing monitoring solutions which are proprietary, difficult to customize, expensive, and require labor-intensive maintenance. While smartphones can radically change environmental and wildlife monitoring, there are a number of technical challenges to address. We present our smartphone-based platform, SoundProof, discuss the challenges of building an autonomous system based on Android phones, and our ongoing efforts to enable environmental monitoring. Our system is built using robust off-the-shelf hardware and mature open-source software where available, to increase scalability and ease of installation. Key features include: * High-quality acoustic signal collection from external microphones to monitor wildlife populations. * Real-time data access, remote programming, and configuration of the field sensor via wireless cellular or WiFi channels, accessible from a website. * Waterproof packaging and solar charger setup for long-term field deployments. * Rich instrumentation of the end-to-end system to quickly identify and debug problems. * Supplementary mesh networking system with long-range wireless antennae to provide coverage when no cell network is available. We have deployed this system to monitor Rufous Crowned Sparrows on Anacapa Island, Chinese Crested Turns on the Matsu Islands in Taiwan, and Ashy Storm Petrels on South East Farallon Island. We have testbeds at two UC Natural Reserves to field

  20. Weight preserving image registration for monitoring disease progression in lung CT.

    Science.gov (United States)

    Gorbunova, Vladlena; Lol, Pechin; Ashraf, Haseem; Dirksen, Asger; Nielsen, Mads; de Bruijne, Marleen

    2008-01-01

    We present a new image registration based method for monitoring regional disease progression in longitudinal image studies of lung disease. A free-form image registration technique is used to match a baseline 3D CT lung scan onto a following scan. Areas with lower intensity in the following scan compared with intensities in the deformed baseline image indicate local loss of lung tissue that is associated with progression of emphysema. To account for differences in lung intensity owing to differences in the inspiration level in the two scans rather than disease progression, we propose to adjust the density of lung tissue with respect to local expansion or compression such that the total weight of the lungs is preserved during deformation. Our method provides a good estimation of regional destruction of lung tissue for subjects with a significant difference in inspiration level between CT scans and may result in a more sensitive measure of disease progression than standard quantitative CT measures.

  1. Monitoring Anthropogenic Ocean Sound from Shipping Using an Acoustic Sensor Network and a Compressive Sensing Approach †

    Science.gov (United States)

    Harris, Peter; Philip, Rachel; Robinson, Stephen; Wang, Lian

    2016-01-01

    Monitoring ocean acoustic noise has been the subject of considerable recent study, motivated by the desire to assess the impact of anthropogenic noise on marine life. A combination of measuring ocean sound using an acoustic sensor network and modelling sources of sound and sound propagation has been proposed as an approach to estimating the acoustic noise map within a region of interest. However, strategies for developing a monitoring network are not well established. In this paper, considerations for designing a network are investigated using a simulated scenario based on the measurement of sound from ships in a shipping lane. Using models for the sources of the sound and for sound propagation, a noise map is calculated and measurements of the noise map by a sensor network within the region of interest are simulated. A compressive sensing algorithm, which exploits the sparsity of the representation of the noise map in terms of the sources, is used to estimate the locations and levels of the sources and thence the entire noise map within the region of interest. It is shown that although the spatial resolution to which the sound sources can be identified is generally limited, estimates of aggregated measures of the noise map can be obtained that are more reliable compared with those provided by other approaches. PMID:27011187

  2. Monitoring and assessment of ingestive chewing sounds for prediction of herbage intake rate in grazing cattle.

    Science.gov (United States)

    Galli, J R; Cangiano, C A; Pece, M A; Larripa, M J; Milone, D H; Utsumi, S A; Laca, E A

    2018-05-01

    Accurate measurement of herbage intake rate is critical to advance knowledge of the ecology of grazing ruminants. This experiment tested the integration of behavioral and acoustic measurements of chewing and biting to estimate herbage dry matter intake (DMI) in dairy cows offered micro-swards of contrasting plant structure. Micro-swards constructed with plastic pots were offered to three lactating Holstein cows (608±24.9 kg of BW) in individual grazing sessions (n=48). Treatments were a factorial combination of two forage species (alfalfa and fescue) and two plant heights (tall=25±3.8 cm and short=12±1.9 cm) and were offered on a gradient of increasing herbage mass (10 to 30 pots) and number of bites (~10 to 40 bites). During each grazing session, sounds of biting and chewing were recorded with a wireless microphone placed on the cows' foreheads and a digital video camera to allow synchronized audio and video recordings. Dry matter intake rate was higher in tall alfalfa than in the other three treatments (32±1.6 v. 19±1.2 g/min). A high proportion of jaw movements in every grazing session (23 to 36%) were compound jaw movements (chew-bites) that appeared to be a key component of chewing and biting efficiency and of the ability of cows to regulate intake rate. Dry matter intake was accurately predicted based on easily observable behavioral and acoustic variables. Chewing sound energy measured as energy flux density (EFD) was linearly related to DMI, with 74% of EFD variation explained by DMI. Total chewing EFD, number of chew-bites and plant height (tall v. short) were the most important predictors of DMI. The best model explained 91% of the variation in DMI with a coefficient of variation of 17%. Ingestive sounds integrate valuable information to remotely monitor feeding behavior and predict DMI in grazing cows.

  3. Efficiency factors for Phoswich based lung monitor using ICRP Voxel phantoms

    International Nuclear Information System (INIS)

    Manohari, M.; Mathiyarasu, R.; Rajagopal, V.; Jose, M.T.; Venkatraman, B.

    2016-01-01

    The actinide contamination in lungs is measured either using array of HPGe detector or Phoswich based lung monitors. This paper discusses the results obtained during numerical calibration of Phoswich based lung counting system using ICRP VOXEL phantoms. The results are also compared with measured efficiency values obtained using LLNL phantom. The efficiency factors of 241 Am present in the lungs for phoswich detector was simulated using ICRP male voxel phantom and compared with experimentally observed values using LLNL Phantom. The observed deviation is 12%. The efficiency of the same for female subjects was estimated using ICRP female voxel phantom for both supine and posterior geometries

  4. Monitoring oiled shorelines in Prince William Sound Alaska, following the Exxon Valdez oil spill

    International Nuclear Information System (INIS)

    Gilfillan, E.S.; Page, D.S.; Harner, E.J.; Boehm, P.D.; Stoker, S.W.

    1993-01-01

    Three types of shoreline monitoring programs were employed to evaluate the recovery of the ecological communities of Prince William Sound (PWS) shorelines after the oil spill: (a) Extensive shoreline surveys conducted (1989--1992) over much of the oiled shoreline to define extent of shoreline oiling and to assess biological conditions; (b) Detailed sampling in 1989 at nonrandomly chosen locations representing a range of oiling conditions (c) Comprehensive shoreline ecology program initiated in 1990 to assess shoreline recovery in Prince William Sound using (1) a rigorous stratified random sampling study design with 64 sites representing 4 shoreline habitats and 4 oiling levels (unoiled, light, moderate, heavy); (2) periodic sampling at 12 nonrandomly chosen sites of particular concern. Biological communities were analyzed to detect differences due to oiling in each of 16 habitat/tide zone combinations. Following the spill, populations of all major species survived as sources for recolonization. Recruitment to oiled shores began in summer 1989. By 1990, shoreline biota in PWS had largely recovered. Estimates of shoreline recovery (biological community indistinguishable from reference) ranged from 91% based on univariate analysis of standard community parameters to 73% based on multivariate correspondence analysis

  5. New developments in the surveillance and diagnostics technology for vibration, structure-borne sound and leakage monitoring systems

    International Nuclear Information System (INIS)

    Gloth, Gerrit

    2009-01-01

    Monitoring and diagnostic systems are of main importance for a safe and efficient operation of nuclear power plants. The author describes new developments with respect to vibration monitoring with a functional extension in the time domain for den secondary circuit, the development of a local system for the surveillance of rotating machines, the structure-borne sound monitoring with improvement of event analysis, esp. the loose part locating, leakage monitoring with a complete system for humidity measurement, and the development of a common platform for all monitoring and diagnostic systems, that allows an efficient access for comparison and cross references.

  6. A more realistic simulation of the performance of the infra-sound monitoring network

    International Nuclear Information System (INIS)

    Le Pichon, A.; Vergoz, J.; Blanc, E.

    2008-01-01

    The first global maps showing the performance of the infra-sound network of the international monitoring system were set in the nineties. Recent measurement of the background noise by the 36 operating stations combined with advanced models of wind give now a more realistic mapping. It has become possible to validate simulations by measuring real events. For instance the explosion that happened in March 2008 in an ammunition storehouse in Albania was detected till Zalesovo (Russia) 4920 km away. These new simulations confirm the detection capability of the network to detect and localize atmospheric explosions whose energy is over 1 kt. It is also shown that the detection performance are very sensitive to both time and places. (A.C.)

  7. Three-dimensional audio-magnetotelluric sounding in monitoring coalbed methane reservoirs

    Science.gov (United States)

    Wang, Nan; Zhao, Shanshan; Hui, Jian; Qin, Qiming

    2017-03-01

    Audio-magnetotelluric (AMT) sounding is widely employed in rapid resistivity delineation of objective geometry in near surface exploration. According to reservoir patterns and electrical parameters obtained in Qinshui Basin, China, two-dimensional and three-dimensional synthetic "objective anomaly" models were designed and inverted with the availability of a modular system for electromagnetic inversion (ModEM). The results revealed that 3-D full impedance inversion yielded the subsurface models closest to synthetic models. One or more conductive targets were correctly recovered. Therefore, conductive aquifers in the study area, including hydrous coalbed methane (CBM) reservoirs, were suggested to be the interpretation signs for reservoir characterization. With the aim of dynamic monitoring of CBM reservoirs, the AMT surveys in continuous years (June 2013-May 2015) were carried out. 3-D inversion results demonstrated that conductive anomalies accumulated around the producing reservoirs at the corresponding depths if CBM reservoirs were in high water production rates. In contrast, smaller conductive anomalies were generally identical with rapid gas production or stopping production of reservoirs. These analyses were in accordance with actual production history of CBM wells. The dynamic traces of conductive anomalies revealed that reservoir water migrated deep or converged in axial parts and wings of folds, which contributed significantly to formations of CBM traps. Then the well spacing scenario was also evaluated based on the dynamic production analysis. Wells distributed near closed faults or flat folds, rather than open faults, had CBM production potential to ascertain stable gas production. Therefore, three-dimensional AMT sounding becomes an attractive option with the ability of dynamic monitoring of CBM reservoirs, and lays a solid foundation of quantitative evaluation of reservoir parameters.

  8. Lung sound analysis can be an index of the control of bronchial asthma

    Directory of Open Access Journals (Sweden)

    Terufumi Shimoda

    2017-01-01

    Conclusions: The E/I LF measurement obtained by LSA is useful as an indicator of changes in airway obstruction and inflammation and can be used for monitoring the therapeutic course of bronchial asthma patients.

  9. Design, development and test of the gearbox condition monitoring system using sound signal processing

    Directory of Open Access Journals (Sweden)

    M Zamani

    2016-09-01

    Full Text Available Introduction One of the ways used for minimizing the cost of maintenance and repairs of rotating industrial equipment is condition monitoring using acoustic analysis. One of the most important problems which always have been under consideration in industrial equipment application is confidence possibility. Each dynamic, electrical, hydraulic or thermal system has certain characteristics which show the normal condition of the machine during function. Any changes of the characteristics can be a signal of a problem in the machine. The aim of condition monitoring is system condition determination using measurements of the signals of characteristics and using this information for system impairment prognostication. There are a lot of ways for condition monitoring of different systems, but sound analysis is accepted and used extensively as a method for condition investigation of rotating machines. The aim of this research is the design and construction of considered gearbox and using of obtaining data in frequency and time spectrum in order to analyze the sound and diagnosis. Materials and Methods This research was conducted at the department of mechanical biosystem workshop at Aboureihan College at Tehran University in February 15th.2015. In this research, in order to investigate the trend of diagnosis and gearbox condition, a system was designed and then constructed. The sound of correct and damaged gearbox was investigated by audiometer and stored in computer for data analysis. Sound measurement was done in three pinions speed of 749, 1050 and 1496 rpm and for correct gearboxes, damage of the fracture of a tooth and a tooth wear. Gearbox design and construction: In order to conduct the research, a gearbox with simple gearwheels was designed according to current needs. Then mentioned gearbox and its accessories were modeled in CATIA V5-R20 software and then the system was constructed. Gearbox is a machine that is used for mechanical power transition

  10. Ethically sound technology? Guidelines for interactive ethical assessment of personal health monitoring.

    Science.gov (United States)

    Palm, Elin; Nordgren, Anders; Verweij, Marcel; Collste, Göran

    2013-01-01

    Novel care-technologies possess a transformational potential. Future care and support may be provided via monitoring technologies such as smart devices, sensors, actors (robots) and Information and Communication Technologies. Such technologies enable care provision outside traditional care institutions, for instance in the homes of patients. Health monitoring may become "personalized" i.e. tailored to the needs of individual care recipients' but may also alter relations between care providers and care recipents, shape and form the care environment and influence values central to health-care. Starting out from a social constructivist theory of technology, an interactive ethical assessment-model is offered. The suggested model supplements a traditional analysis based on normative ethical theory (top-down approach) with interviews including relevant stakeholders (a bottom-up approach). This method has been piloted by small-scale interviews encircling stakeholder perspectives on three emerging technologies: (1) Careousel, a smart medicine-management device, (2) Robot Giraff, an interactive and mobile communication-device and (3) I-Care, a care-software that combines alarm and register system. By incorporating stakeholder perspectives into the analysis, the interactive ethical assessment model provides a richer understanding of the impact of PHM-technologies on ethical values than a traditional top-down model. If the assessment is conducted before the technology has reached the market - preferably in close interaction with developers and users - ethically sound technologies may be obtained.

  11. Non-Contact Monitoring of Heart and Lung Activity by Magnetic Induction Measurement

    Directory of Open Access Journals (Sweden)

    M. Steffen

    2008-01-01

    Full Text Available In many clinical applications, the monitoring of heart and lung activity is of vital importance. State-of-the-art monitoring involves the use of electrodes or other contact based sensors (electrocardiogram (ECG, impedance cardiography (ICG, pulse oximetry or equivalent. With the equipment that is used, side effects like skin irritation, difficult application or additional cabling may occur. In contrast, this paper describes a method for non-contact monitoring of heart and lung activity, which is solely based on magnetic induction. This method allows simultaneous monitoring of heart and lung activity, and has the potential of an integrated application in a personal healthcare scenario. To illustrate the performance, a simple test-setup has been developed and the first results are presented here (some of which have been previously presented on the Poster 2008 [10]. 

  12. Monitoring lung contusion in a porcine polytrauma model using EIT: an application study.

    Science.gov (United States)

    Santos, Susana Aguiar; Wembers, Carlos Castelar; Horst, Klemens; Pfeifer, Roman; Simon, Tim-Philipp; Pape, Hans-Christoph; Hildebrand, Frank; Czaplik, Michael; Leonhardt, Steffen; Teichmann, Daniel

    2017-07-26

    Lung contusion is the most common lung injury following blunt chest trauma which, in turn, is associated with high mortality rates (Gavelli et al 2002 Eur. Radiol. 12 1273-94). Lung contusion is characterized by hemorrhage and edema with consecutively reduced compliance. Objective and Approach: In this study, unilateral lung contusion and other traumata were induced in 12 pigs by using a bolt gun machine. To investigate the pathophysiological consequences of lung contusion, information on clinical parameters was collected and monitored regularly while animals were additionally monitored with electrical impedance tomography (EIT) before trauma, and at 4, 24, 48 and 72 h after polytrauma. Statistical analyses showed significant differences between the measurement time points in terms of lung compliance ([Formula: see text]) and in global EIT parameters, such as absolute global impedance (aGlobImp) ([Formula: see text]), tidal impedance variation (TIV) ([Formula: see text]) and the center of ventilation (CoV) ([Formula: see text]). Additionally, distinct analyses for the left (non-injured) and right (injured) lung were also performed. In this context, during the progress of lung contusion, significant changes were found for the injured lung in TIV ([Formula: see text]), global inhomogeneity ([Formula: see text]), regional ventilation delay ([Formula: see text]), CoV ([Formula: see text]) and in regions of non-ventilation (rNoVent) ([Formula: see text]). Furthermore, TIV and rNoVent were capable to differentiate the injured and the contralateral healthy lung at 4 and 24 h after injury (TIV: [Formula: see text] and [Formula: see text]; rNoVent: [Formula: see text] and [Formula: see text]). TIV reached a sensitivity of 82% (specificity of 100%) at 4 h and sensitivity of 82% (specificity of 82%) at 24 h after injury, in detecting lung contusion specific consequences. The results indicate that EIT might be a valuable tool to detect and to monitor lung injuries

  13. Nonintrusive gas monitoring in neonatal lungs using diode laser spectroscopy: feasibility study.

    Science.gov (United States)

    Lewander, Märta; Bruzelius, Anders; Svanberg, Sune; Svanberg, Katarina; Fellman, Vineta

    2011-12-01

    A feasibility study on noninvasive, real-time monitoring of gases in lungs of preterm infants is reported, where a laser-spectroscopic technique using diode lasers tuned to oxygen and water vapor absorption lines was employed on realistic tissue phantoms. Our work suggests that the technique could provide a new possibility for surveillance of the lung function of preterm infants, in particular the oxygenation, which is of prime importance in this patient group.

  14. Postrelease monitoring of radio-instrumented sea otters in Prince William Sound

    Science.gov (United States)

    Monnett, C.; Rotterman, L.M.; Stack, C.; Monson, Daniel H.; Bayha, Keith; Kormendy, Jennifer

    1990-01-01

    Sea otters (Enhydra lutris) that were captured in western Prince William Sound (PWS) or the Gulf of Alaska, treated, and held in captivity at the temporary rehabilitation centers established in response to the T/V Exxon Valdez oil spill were instrumented with radio transmitters, released into eastern PWS, and monitored by radiotelemetry. We undertook the present study to gain information for guiding the release of the remaining captive otters and evaluating the efficacy of sea otter rehabilitation after exposure to crude oil. Radio transmitters were attached to the flippers of seven sea otters released in May 1989 and monitored for periods of a few hours to more than 60 days. However, little was learned about the fate of these animals because the radio transmitters used proved unreliable. Forty-five additional sea otters from the rehabilitation centers were implanted with radio transmitters, released into northeastern PWS and monitored for 8 months. During the first 20 days after the first release of these implanted otters (n = 21), they were more mobile than wild-caught and released sea otters studied in PWS, from 1984 through 1990. All were alive and vigorous at the end of the 20-day period. Tracking of all 45 implanted sea otters during the 8-month period showed that the otters remained highly mobile. Many (46.6%) crossed into western PWS. However, by the end of the 8 months, 12 of the instrumented otters were dead and 9 were missing. One radio failed. These mortality and missing rates are much higher than those normally observed for adult sea otters in PWS. The death rate was highest in winter. These data suggest that, despite the tremendous amount of money and energy directed toward the treatment and care of these animals, the sea otters released from the centers were not completely rehabilitated, that is, not returned to a normal state. We recommend that future policies focus on preventing otters from becoming oiled, rather than attempting to treat them

  15. Counting efficiency of the lung monitor for sup 2 sup 4 sup 1 Am

    CERN Document Server

    Kinase, S; Sekiguchi, M

    2003-01-01

    The counting efficiencies of two lung monitor systems, phoswich detector system and germanium detector system, were measured for lungs and liver loaded with sup 2 sup 4 sup 1 Am in the Japan Atomic Energy Research Institute (JAERI) phantom. It was found that the germanium detector system for sup 2 sup 4 sup 1 Am loaded lungs counting gives the full-energy peak predominated by the absorption of the gamma-ray photon in a single photoelectric interaction and is less sensitive to sup 2 sup 4 sup 1 Am loaded liver. The sup 2 sup 4 sup 1 Am loaded lung activities could be reasonably estimated using germanium detector system rather than phoswich detector system.

  16. Short communication. Platform for bee-hives monitoring based on sound analysis. A perpetual warehouse for swarms daily activity

    Energy Technology Data Exchange (ETDEWEB)

    Atauri Mezquida, D.; Llorente Martinez, J.

    2009-07-01

    Bees and beekeeping are suffering a global crisis. Constant information on swarms conditions would be a key to study new diseases like colony collapse disorder and to develop new beekeeping tools to improve the hive management and make it more efficient. A platform for beehives monitoring is presented. It is based on the analysis of the colonies buzz which is registered by a bunch of sensors sending the data to a common database. Data obtained through sound processing shows plenty of patterns and tendency lines related to colonies activities and their conditions. It shows the potential of the sound as a swarm activity gauge. The goal of the platform is the possibility to store information about the swarms activity. The objective is to build a global net of monitored hives covering apiaries with different climates, razes and managements. (Author) 21 refs.

  17. Diode laser spectroscopy for noninvasive monitoring of oxygen in the lungs of newborn infants.

    Science.gov (United States)

    Svanberg, Emilie Krite; Lundin, Patrik; Larsson, Marcus; Åkeson, Jonas; Svanberg, Katarina; Svanberg, Sune; Andersson-Engels, Stefan; Fellman, Vineta

    2016-04-01

    Newborn infants may have pulmonary disorders with abnormal gas distribution, e.g., respiratory distress syndrome. Pulmonary radiography is the clinical routine for diagnosis. Our aim was to investigate a novel noninvasive optical technique for rapid nonradiographic bedside detection of oxygen gas in the lungs of full-term newborn infants. Laser spectroscopy was used to measure contents of oxygen gas (at 760 nm) and of water vapor (at 937 nm) in the lungs of 29 healthy newborn full-term infants (birth weight 2,900-3,900 g). The skin above the lungs was illuminated using two low-power diode lasers and diffusely emerging light was detected with a photodiode. Of the total 390 lung measurements performed, clear detection of oxygen gas was recorded in 60%, defined by a signal-to-noise ratio of >3. In all the 29 infants, oxygen was detected. Probe and detector positions for optimal pulmonary gas detection were determined. There were no differences in signal quality with respect to gender, body side or body weight. The ability to measure pulmonary oxygen content in healthy full-term neonates with this technique suggests that with further development, the method might be implemented in clinical practice for lung monitoring in neonatal intensive care.

  18. The effect of surgery on lung volume and conventional monitoring parameters in ventilated newborn infants.

    Science.gov (United States)

    Proquitté, H; Freiberger, O; Yilmaz, S; Bamberg, C; Degenhardt, P; Roehr, C C; Wauer, R R; Schmalisch, G

    2010-05-01

    In newborn infants, thoraco-abdominal surgery is a serious intervention with respect to gas exchange and lung mechanics. This prospective clinical study compared surgery-induced changes in functional residual capacity (FRC) and ventilation inhomogeneity (VI) indices with changes in conventional monitoring parameters. Of 29 ventilated newborns (mean weight 2,770+/-864 g at surgery), 13, nine and seven underwent thoracic, abdominal or congenital diaphragmatic hernia (CDH) surgery, respectively. The multiple breath washout (MBWO) technique using heptafluoropropane as tracer gas (Babylog 8000; Dräger, Lübeck, Germany) was performed ventilatory monitoring parameters. FRC decreased in non-CDH infants, while FRC increased and VI indices decreased in CDH infants. Despite improvements, the differences in FRC and VI between CDH and non-CDH infants indicated persistent impaired lung function in CHD infants. MBWO can be advantageously used to measure the effect of surgery on the lung. While FRC and VI indices changed following surgery, conventional monitoring parameters did not.

  19. Efficacy of lung volume optimization maneuver monitored by optoelectronic pletismography in the management of congenital diaphragmatic hernia

    Directory of Open Access Journals (Sweden)

    G. Lista

    2017-01-01

    We report a case of left CDH with severe lung hypoplasia, managed applying open lung strategy in HFOV (pre-surgery period and in Assist-Control with Volume Guarantee (post-surgery period, guided by SpO2 changes, TcPO2 and TcPCO2 monitoring. Opto-electronic plethysmography was used to measure end-expiratory chest wall volume changes (ΔEEcw related to lung volume variations occurring during pressure changes. OEP confirmed the efficacy of using SpO2 and transcutaneous gas monitoring during this recruitment maneuver.

  20. Performance monitoring in lung cancer patients pre- and post-chemotherapy using fine-grained electrophysiological measures

    Directory of Open Access Journals (Sweden)

    M. Simó

    Full Text Available No previous event-related potentials (ERPs study has explored the error-related negativity (ERN - an ERP component indexing performance monitoring - associated to cancer and chemotherapy-induced cognitive impairment in a lung cancer population. The aim of this study was to examine differences in performance monitoring in a small-cell lung cancer group (SCLC, C+ 1-month following chemotherapy and two control groups: a non-small cell lung cancer patient group (NSCLC, C− prior to chemotherapy and a healthy control group (HC.Seventeen SCLC (C+ underwent a neuropsychological assessment and an ERP study using a flanker and a stop-signal paradigm. This group was compared to fifteen age-, gender- and education-matched NSCLC (C− and eighteen HC.Between 20 and 30% of patients in both lung cancer groups (C+ and C− met criteria for cognitive impairment. Concerning ERPs, lung cancer patients showed lower overall hit rate and a severe ERN amplitude reduction compared to HC.Lung cancer patients exhibited an abnormal pattern of performance monitoring thus suggesting that chemotherapy and especially cancer itself, may contribute to cognitive deterioration. ERN appeared as an objective laboratory tool sensitive to cognitive dysfunction in cancer population. Keywords: Event-related potentials-ERP, Error-related negativity (ERN, Performance monitoring, Lung cancer, Cognitive impairment, Chemobrain

  1. Sound and sound sources

    DEFF Research Database (Denmark)

    Larsen, Ole Næsbye; Wahlberg, Magnus

    2017-01-01

    There is no difference in principle between the infrasonic and ultrasonic sounds, which are inaudible to humans (or other animals) and the sounds that we can hear. In all cases, sound is a wave of pressure and particle oscillations propagating through an elastic medium, such as air. This chapter...... is about the physical laws that govern how animals produce sound signals and how physical principles determine the signals’ frequency content and sound level, the nature of the sound field (sound pressure versus particle vibrations) as well as directional properties of the emitted signal. Many...... of these properties are dictated by simple physical relationships between the size of the sound emitter and the wavelength of emitted sound. The wavelengths of the signals need to be sufficiently short in relation to the size of the emitter to allow for the efficient production of propagating sound pressure waves...

  2. Monitoring of aquifer pump tests with Magnetic Resonance Sounding (MRS): a synthetic case study

    DEFF Research Database (Denmark)

    Herckenrath, Daan; Auken, E.; Bauer-Gottwein, Peter

    2011-01-01

    Magnetic Resonance Sounding (MRS) can provide valuable data to constrain and calibrate groundwater flow and transport models. With this non-invasive geophysical technique, measurements of water content and hydraulic conductivity can be obtained. We developed a hydrogeophyiscal forward method, which...... calculates the MRS-signal generated by an aquifer pump test. A synthetic MRS-dataset was subsequently used to determine the hydrogeological parameters in an inverse parameter estimation approach. This was done for a virtual pump test with a partially and a fully penetrating well. With the MRS data we were...

  3. Radiation exposure by monitors and effects of whistling sound on hearing at workplaces in TV and film production sectors

    International Nuclear Information System (INIS)

    Strasser, H.

    1988-01-01

    Information transmission by means of VDUs, spreading at present rapidly in office work and some branches of the industrial production, is not only an auxiliary means but the essential destination and objective of working activities in specific areas of the media sector. By the progression of the video technique a further concentration of VDT work and the increasing gravity of all advantages and disadvantages is to be expected in the film and TV sectors. The real radiation exposure of the technical staff involved in working with and at monitors and potential risks of hearing by whistling sounds sent out by these apparatuses are analysed and evaluated. Experiences in health hazards by radiation from VDUs in office work had to be adapted adequately to the specific working conditions at work places in film and TV productions. (orig./HP) [de

  4. Passive acoustic monitoring of the temporal variability of odontocete tonal sounds from a long-term marine observatory.

    Directory of Open Access Journals (Sweden)

    Tzu-Hao Lin

    Full Text Available The developments of marine observatories and automatic sound detection algorithms have facilitated the long-term monitoring of multiple species of odontocetes. Although classification remains difficult, information on tonal sound in odontocetes (i.e., toothed whales, including dolphins and porpoises can provide insights into the species composition and group behavior of these species. However, the approach to measure whistle contour parameters for detecting the variability of odontocete vocal behavior may be biased when the signal-to-noise ratio is low. Thus, methods for analyzing the whistle usage of an entire group are necessary. In this study, a local-max detector was used to detect burst pulses and representative frequencies of whistles within 4.5-48 kHz. Whistle contours were extracted and classified using an unsupervised method. Whistle characteristics and usage pattern were quantified based on the distribution of representative frequencies and the composition of whistle repertoires. Based on the one year recordings collected from the Marine Cable Hosted Observatory off northeastern Taiwan, odontocete burst pulses and whistles were primarily detected during the nighttime, especially after sunset. Whistle usage during the nighttime was more complex, and whistles with higher frequency were mainly detected during summer and fall. According to the multivariate analysis, the diurnal variation of whistle usage was primarily related to the change of mode frequency, diversity of representative frequency, and sequence complexity. The seasonal variation of whistle usage involved the previous three parameters, in addition to the diversity of whistle clusters. Our results indicated that the species and behavioral composition of the local odontocete community may vary among seasonal and diurnal cycles. The current monitoring platform facilitates the evaluation of whistle usage based on group behavior and provides feature vectors for species and

  5. Magnetic induction pneumography: a planar coil system for continuous monitoring of lung function via contactless measurements

    Directory of Open Access Journals (Sweden)

    Doga Gursoy

    2010-11-01

    Full Text Available Continuous monitoring of lung function is of particular interest to the mechanically ventilated patients during critical care. Recent studies have shown that magnetic induction measurements with single coils provide signals which are correlated with the lung dynamics and this idea is extended here by using a 5 by 5 planar coil matrix for data acquisition in order to image the regional thoracic conductivity changes. The coil matrix can easily be mounted onto the patient bed, and thus, the problems faced in methods that use contacting sensors can readily be eliminated and the patient comfort can be improved. In the proposed technique, the data are acquired by successively exciting each coil in order to induce an eddy-current density within the dorsal tissues and measuring the corresponding response magnetic field strength by the remaining coils. The recorded set of data is then used to reconstruct the internal conductivity distribution by means of algorithms that minimize the residual norm between the estimated and measured data. To investigate the feasibility of the technique, the sensitivity maps and the point spread functions at different locations and depths were studied. To simulate a realistic scenario, a chest model was generated by segmenting the tissue boundaries from NMR images. The reconstructions of the ventilation distribution and the development of an edematous lung injury were presented. The imaging artifacts caused by either the incorrect positioning of the patient or the expansion of the chest wall due to breathing were illustrated by simulations.

  6. Therapy monitoring using dynamic MRI: Analysis of lung motion and intrathoracic tumor mobility before and after radiotherapy

    Energy Technology Data Exchange (ETDEWEB)

    Plathow, Christian [Eberhard-Karls University Tuebingen, Department of Diagnostic Radiology, Tuebingen (Germany); German Cancer Research Center, Department of Radiology, Heidelberg (Germany); Hof, Holger; Kuhn, Sabine [University of Heidelberg, Department of Radiation Therapy, Clinic for Thoracic Diseases, Heidelberg (Germany); Puderbach, Michael; Ley, Sebastian; Biederer, Juergen; Kauczor, Hans-Ulrich [German Cancer Research Center, Department of Radiology, Heidelberg (Germany); Claussen, Claus D.; Schaefer, Juergen [Eberhard-Karls University Tuebingen, Department of Diagnostic Radiology, Tuebingen (Germany); Huber, Peter E. [University of Heidelberg, Department of Radiation Therapy, Clinic for Thoracic Diseases, Heidelberg (Germany); German Cancer Research Center, Department of Radiation Oncology, Heidelberg (Germany); Tuengerthal, Siegfried [University of Heidelberg, Department of Radiology, Heidelberg (Germany)

    2006-09-15

    A frequent side effect after radiotherapy of lung tumors is a decrease of pulmonary function accompanied by dyspnea due to developing lung fibrosis. The aim of this study was to monitor lung motion as a correlate of pulmonary function and intrathoracic tumor mobility before and after radiotherapy (RT) using dynamic MRI (dMRI). Thirty-five patients with stage I non-small-cell lung carcinoma were examined using dMRI (trueFISP; three images/s). Tumors were divided into T1 and T2 tumors of the upper, middle and lower lung region (LR). Maximum craniocaudal (CC) lung dimensions and tumor mobility in three dimensions were monitored. Vital capacity (VC) was measured and correlated using spirometry. Before RT, the maximum CC motion of the tumor-bearing hemithorax was 5.2{+-}0.9 cm if the tumor was located in the lower LR (middle LR: 5.5{+-}0.8 cm; upper LR: 6.0{+-}0.6 cm). After RT, lung motion was significantly reduced in the lower LR (P<0.05). Before RT, the maximum CC tumor mobility was significantly higher in tumors of the lower LR 2.5{+-}0.6 vs. 2.0{+-}0.3 cm (middle LR; P<0.05) vs. 0.7{+-}0.2 cm (upper LR; P<0.01). After RT, tumor mobility was significantly reduced in the lower LR (P<0.01) and in T2 tumor patients (P<0.05). VC showed no significant changes. dMRI is capable of monitoring changes in lung motion that were not suspected from spirometry. This might make the treatment of side effects possible at a very early stage. Changes of lung motion and tumor mobility are highly dependent on the tumor localization and tumor diameter. (orig.)

  7. Therapy monitoring using dynamic MRI: Analysis of lung motion and intrathoracic tumor mobility before and after radiotherapy

    International Nuclear Information System (INIS)

    Plathow, Christian; Hof, Holger; Kuhn, Sabine; Puderbach, Michael; Ley, Sebastian; Biederer, Juergen; Kauczor, Hans-Ulrich; Claussen, Claus D.; Schaefer, Juergen; Huber, Peter E.; Tuengerthal, Siegfried

    2006-01-01

    A frequent side effect after radiotherapy of lung tumors is a decrease of pulmonary function accompanied by dyspnea due to developing lung fibrosis. The aim of this study was to monitor lung motion as a correlate of pulmonary function and intrathoracic tumor mobility before and after radiotherapy (RT) using dynamic MRI (dMRI). Thirty-five patients with stage I non-small-cell lung carcinoma were examined using dMRI (trueFISP; three images/s). Tumors were divided into T1 and T2 tumors of the upper, middle and lower lung region (LR). Maximum craniocaudal (CC) lung dimensions and tumor mobility in three dimensions were monitored. Vital capacity (VC) was measured and correlated using spirometry. Before RT, the maximum CC motion of the tumor-bearing hemithorax was 5.2±0.9 cm if the tumor was located in the lower LR (middle LR: 5.5±0.8 cm; upper LR: 6.0±0.6 cm). After RT, lung motion was significantly reduced in the lower LR (P<0.05). Before RT, the maximum CC tumor mobility was significantly higher in tumors of the lower LR 2.5±0.6 vs. 2.0±0.3 cm (middle LR; P<0.05) vs. 0.7±0.2 cm (upper LR; P<0.01). After RT, tumor mobility was significantly reduced in the lower LR (P<0.01) and in T2 tumor patients (P<0.05). VC showed no significant changes. dMRI is capable of monitoring changes in lung motion that were not suspected from spirometry. This might make the treatment of side effects possible at a very early stage. Changes of lung motion and tumor mobility are highly dependent on the tumor localization and tumor diameter. (orig.)

  8. Nano-enabled paper humidity sensor for mobile based point-of-care lung function monitoring.

    Science.gov (United States)

    Bhattacharjee, Mitradip; Nemade, Harshal B; Bandyopadhyay, Dipankar

    2017-08-15

    The frequency of breathing and peak flow rate of exhaled air are necessary parameters to detect chronic obstructive pulmonary diseases (COPDs) such as asthma, bronchitis, or pneumonia. We developed a lung function monitoring point-of-care-testing device (LFM-POCT) consisting of mouthpiece, paper-based humidity sensor, micro-heater, and real-time monitoring unit. Fabrication of a mouthpiece of optimal length ensured that the exhaled air was focused on the humidity-sensor. The resistive relative humidity sensor was developed using a filter paper coated with nanoparticles, which could easily follow the frequency and peak flow rate of the human breathing. Adsorption followed by condensation of the water molecules of the humid air on the paper-sensor during the forced exhalation reduced the electrical resistance of the sensor, which was converted to an electrical signal for sensing. A micro-heater composed of a copper-coil embedded in a polymer matrix helped in maintaining an optimal temperature on the sensor surface. Thus, water condensed on the sensor surface only during forcible breathing and the sensor recovered rapidly after the exhalation was complete by rapid desorption of water molecules from the sensor surface. Two types of real-time monitoring units were integrated into the device based on light emitting diodes (LEDs) and smart phones. The LED based unit displayed the diseased, critical, and fit conditions of the lungs by flashing LEDs of different colors. In comparison, for the mobile based monitoring unit, an application was developed employing an open source software, which established a wireless connectivity with the LFM-POCT device to perform the tests. Copyright © 2017 Elsevier B.V. All rights reserved.

  9. Broadcast sound technology

    CERN Document Server

    Talbot-Smith, Michael

    1990-01-01

    Broadcast Sound Technology provides an explanation of the underlying principles of modern audio technology. Organized into 21 chapters, the book first describes the basic sound; behavior of sound waves; aspects of hearing, harming, and charming the ear; room acoustics; reverberation; microphones; phantom power; loudspeakers; basic stereo; and monitoring of audio signal. Subsequent chapters explore the processing of audio signal, sockets, sound desks, and digital audio. Analogue and digital tape recording and reproduction, as well as noise reduction, are also explained.

  10. A Comparative Study of the Monitoring of a Self Aligning Spherical Journal using Surface Vibration, Airborne Sound and Acoustic Emission

    International Nuclear Information System (INIS)

    Raharjo, P; Tesfa, B; Gu, F; Ball, A D

    2012-01-01

    A Self aligning spherical journal bearing is a plain bearing which has spherical surface contact that can be applied in high power industrial machinery. This type of bearing can accommodate a misalignment problem. The journal bearing faults degrade machine performance, decrease life time service and cause unexpected failure which are dangerous for safety issues. Non-intrusive measurements such as surface vibration (SV), airborne sound (AS) and acoustic emission (AE) measurement are appropriate monitoring methods for early stage journal bearing fault in low, medium and high frequency. This paper focuses on the performance comparison using SV, AS and AE measurements in monitoring a self aligning spherical journal bearing for normal and faulty (scratch) conditions. It examines the signals in the time domain and frequency domain and identifies the frequency ranges for each measurement in which significant changes are observed. The results of SV, AS and AE experiments indicate that the spectrum can be used to detect the differences between normal and faulty bearing. The statistic parameter shows that RMS value and peak value for faulty bearing is higher than normal bearing.

  11. Towards lung EIT image segmentation: automatic classification of lung tissue state from analysis of EIT monitored recruitment manoeuvres

    International Nuclear Information System (INIS)

    Grychtol, Bartłomiej; Wolf, Gerhard K; Arnold, John H; Adler, Andy

    2010-01-01

    There is emerging evidence that the ventilation strategy used in acute lung injury (ALI) makes a significant difference in outcome and that an inappropriate ventilation strategy may produce ventilator-associated lung injury. Most harmful during mechanical ventilation are lung overdistension and lung collapse or atelectasis. Electrical impedance tomography (EIT) as a non-invasive imaging technology may be helpful to identify lung areas at risk. Currently, no automated method is routinely available to identify lung areas that are overdistended, collapsed or ventilated appropriately. We propose a fuzzy logic-based algorithm to analyse EIT images obtained during stepwise changes of mean airway pressures during mechanical ventilation. The algorithm is tested on data from two published studies of stepwise inflation–deflation manoeuvres in an animal model of ALI using conventional and high-frequency oscillatory ventilation. The timing of lung opening and collapsing on segmented images obtained using the algorithm during an inflation–deflation manoeuvre is in agreement with well-known effects of surfactant administration and changes in shunt fraction. While the performance of the algorithm has not been verified against a gold standard, we feel that it presents an important first step in tackling this challenging and important problem

  12. Towards lung EIT image segmentation: automatic classification of lung tissue state from analysis of EIT monitored recruitment manoeuvres.

    Science.gov (United States)

    Grychtol, Bartłomiej; Wolf, Gerhard K; Adler, Andy; Arnold, John H

    2010-08-01

    There is emerging evidence that the ventilation strategy used in acute lung injury (ALI) makes a significant difference in outcome and that an inappropriate ventilation strategy may produce ventilator-associated lung injury. Most harmful during mechanical ventilation are lung overdistension and lung collapse or atelectasis. Electrical impedance tomography (EIT) as a non-invasive imaging technology may be helpful to identify lung areas at risk. Currently, no automated method is routinely available to identify lung areas that are overdistended, collapsed or ventilated appropriately. We propose a fuzzy logic-based algorithm to analyse EIT images obtained during stepwise changes of mean airway pressures during mechanical ventilation. The algorithm is tested on data from two published studies of stepwise inflation-deflation manoeuvres in an animal model of ALI using conventional and high-frequency oscillatory ventilation. The timing of lung opening and collapsing on segmented images obtained using the algorithm during an inflation-deflation manoeuvre is in agreement with well-known effects of surfactant administration and changes in shunt fraction. While the performance of the algorithm has not been verified against a gold standard, we feel that it presents an important first step in tackling this challenging and important problem.

  13. Sound the alarm : monitoring system's real-time data reduces well downtime

    Energy Technology Data Exchange (ETDEWEB)

    Harrison, L.

    2008-10-15

    This article presented a new electrical heating element tool used to boost performance at low-producing wells. The down hole tool (DHT) was designed to generate steam underground in order to avoid the energy losses associated with above-ground equipment. The tool operates like an oven element but is connected to a computerized well-monitoring system in order to ensure that heat is evenly distributed. The DHT is equipped with an Optiview monitoring system designed to provide continuous readouts of near real time data. The system can also be customized to deliver messages to telephones, computers, or alarm systems. Changes in hydraulic torque, flow rates, tank levels, speeds, temperatures and hydraulic pressures can be set within ranges in order to optimize oil and gas well production by reducing operating costs and increasing equipment efficiencies. Use of the tool has during tests has minimized the need for well servicing. The patent pending technology is also being investigated for its use in water disposal and other pump-to-surface units. It was concluded that use of the technology will allow oil and gas managers to determine the status of wells in remote locations. 1 fig.

  14. The value of serial FDG PET on therapeutic evaluation and relapse monitoring of lung cancer

    International Nuclear Information System (INIS)

    Zhu Zhaohui; Cheng Wuying; Cui Ruixue; Chen Xin; Hao Li; Dang Yonghong; Zhe Fu; Wang Bocheng

    2004-01-01

    Purpose: A retrospective study was designed to investigate the value of serial FDG PET on therapeutic evaluation and relapse monitoring of lung cancer, and the influence factors to the evaluation and follow-up were also analyzed. Methods: Nineteen patients with confirmed lung cancer were included in the study, and they accepted a total of 87 FDG PET scans, with 3 to 12 times for each patient. The follow-up intervals of FDG PET varied from 14 days to 32 months, and 51 of 68 intervals were within 6 months with a mean of 3.3 months. The PET images of serial studies were analyzed with both visual and semi-quantitative Methods, and they were compared with other imaging techniques (CT, MRI and/or bone scan) and clinical follow-ups. Results: By providing metabolic information, FDG PET detected tumors with high contrast to normal tissue, and the serial examinations helped 9 patients in detecting and evaluating lesions in areas with complicated anatomic structures, such as lung hilus, mediastinum, supraclavicular and abdomen. PET also showed more accuracy and sensitivity than bone scan, CT or MRI in evaluation of bone metastases in two cases. Serial FDG PET was also helpful to the cases in complicated conditions with necrosis, fibrosis or changes of anatomic structures after multiple therapies. In two cases, the follow-up studies confirmed the metastases in the incision wound, which had increasing uptake while it decreased in the repairing wound tissue. By analyzing metabolism of the lesions, PET also showed changes in 3 cases, while they were unconcluded by CT and/or MRI. In some circumstances, benign uptake of FDG influenced the evaluation and monitoring. Inflammation after radiotherapy showed high uptake in 7 cases, and influenced the evaluation of therapy in the serial examinations. Recent use of granulocyte clone stimulation factor (G-CSF) caused diffuse high uptake in bone marrow, and it covered the bone metastases in one case. And in other two cases, diffuse high

  15. Performance of long-term CT monitoring in diagnosing bronchiolitis obliterans after lung transplantation

    Energy Technology Data Exchange (ETDEWEB)

    Berstad, Audun E. [Department of Radiology, Rikshospitalet University Hospital, Sognsvannsveien 20, N-0027 Oslo (Norway)]. E-mail: a.e.berstad@medisin.uio.no; Aalokken, Trond Mogens [Department of Radiology, Rikshospitalet University Hospital, Sognsvannsveien 20, N-0027 Oslo (Norway); Kolbenstvedt, Alf [Department of Radiology, Rikshospitalet University Hospital, Sognsvannsveien 20, N-0027 Oslo (Norway); Bjortuft, Oystein [Department of Thoracic Medicine, Rikshospitalet University Hospital, Sognsvannsveien 20, N-0027 Oslo (Norway)

    2006-04-15

    Aim: The purpose of the study was to evaluate the ability of CT, including expiratory scans with minimum intensity projection in predicting the development of bronchiolitis obliterans syndrome after lung transplantation. Materials and methods: Forty consecutive patients, 29 bilateral and 11 single lung transplanted, were followed-up with regular scans for a median of 36 months. Air trapping was evaluated on expiratory scans constructed from two short spiral scans with minimum intensity projection-technique, one at the level of the carina and the other midway between the right diaphragm and the carina. Air trapping was scored on a 16-point scale. Bronchiolitis obliterans syndrome was diagnosed according to established clinical criteria and quantified spirometrically. Results: Bronchiolitis obliterans syndrome developed in 17 patients (43%) after a median of 12 months. Air trapping and bronchiectasis was seen before the diagnosis of bronchiolitis obliterans syndrome in only two and one patient, respectively. Interobserver agreement for air trapping score was good (kappa = 0.65). Air trapping scores performed significantly better than that achieved by chance alone in determining the presence of bronchiolitis obliterans syndrome (P = 0.0025). An air trapping score of 4 or more provided the best results with regard to sensitivity and specificity in diagnosing bronchiolitis obliterans syndrome. The sensitivity, specificity, positive and negative predictive values of an air trapping of 4 or more in the diagnosis of bronchiolitis obliterans syndrome were 77, 74, 68 and 81%, respectively. Conclusion: Expiratory CT scans with minimum intensity projection-reconstruction did not predict the development of bronchiolitis obliterans syndrome in most patients. The findings seriously limit the clinical usefulness of long-term CT monitoring for diagnosing bronchiolitis obliterans syndrome after lung transplantation.

  16. SU-E-T-31: Alternative VMAT Technique Reduces Total Monitor Units for Lung SBRT

    Energy Technology Data Exchange (ETDEWEB)

    Happersett, L; Mechalakos, J; Kuo, L; Zhang, P; Rimner, A [Memorial Sloan-Kettering Cancer Center, NY, NY (United States)

    2014-06-01

    Purpose: To investigate an alternative approach to VMAT optimization for hypofractionation lung treatment which increases average aperture opening and results in lower total Monitor Units (MU) without significantly sacrificing plan quality. Methods: Benchmark Volumetric Modulated Arc Therapy (bVMAT) plans were generated for 10 lung Stereotactic Body radiotherapy (SBRT) cases using Eclipse Version 11.0.42 (Varian Medical Systems) without a maximum MU constraint. Prescriptions ranged from 40 to 54Gy in 3 to 5 fractions. AAA dose calculation and PRO fluence based optimization was utilized. Two comparison VMAT plans were generated for each case, one that forced an initial “open” mlc aperture conformal to the tumor as a starting condition (oVMAT) with similar optimization parameters and arc geometries, and one that repeated the bVMAT optimization but added a maximum MU constraint (muVMAT). All plans used two arcs with lengths between 168 to 230 degrees. PTV D 95% and Dmean, lung V20 Gy, chest wall V30 Gy, average aperture opening and MU's were compared. Statistical significance was evaluated using Wilcoxon signed rank test. Results: Average PTV D(95), PTV mean and lung V20Gy over all plans was 99.2 ± 1.7%, 103.3 ± 0.6% and 7.8 ± 2.4% respectively. The average chest wall V30Gy was 61 ± 61 cc and ranged between 0 to 166 cc. There were no significant differences between the three techniques for the dosimetric quantities. MUs were reduced by 11 ±11% (p<0.01) and 25 ± 5% (p<0.01) and the average aperture size was increased by 13.7 ± 14% (p=0.02) and 35.8 ± 10% (p<0.01) with muVMAT and oVMAT, respectively, compared to bVMAT. Conclusion: oVMAT and muVMAT techniques were both able to increase average aperture size and reduce total MU compared to the benchmark VMAT plan, but the magnitude of the changes observed for oVMAT was larger.

  17. Ambient Monitoring for Sinclair and Dyes Inlets, Puget Sound, Washington: Chemical Analyses for 2010 Regional Mussel Watch (AMB02)

    Energy Technology Data Exchange (ETDEWEB)

    Brandenberger, Jill M. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Kuo, Li-Jung [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Suslick, Carolynn R. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Johnston, Robert K. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States)

    2010-10-20

    The Puget Sound Naval Shipyard & Intermediate Maintenance Facility (PSNS&IMF) and Naval Base Kitsap-Bremerton (Shipyard) located in Bremerton, WA are committed to a culture of continuous process improvement for all aspects of Shipyard operations, including reducing the releases of hazardous materials and waste in discharges from the Shipyard. Under the Project ENVVEST Final Project Agreement, a cooperative project among PSNS&IMF, the Environmental Protection Agency (EPA), and the Washington State Department of Ecology (Ecology), and local stakeholders (US Navy, EPA and Ecology 2002) has been helping to improve the environmental quality of the Sinclair and Dyes Inlet Watershed (ENVVEST 2006). An ambient monitoring program for sediment, water, and indigenous mussels began in 2009 to assess the status and trend of ecological resources, assess the effectiveness of cleanup and pollution control measures, and determine if discharges from all sources are protective of beneficial uses including aquatic life. This document presents the 2010 chemical residue data and stable isotopes of carbon (δ13C) and nitrogen (δ15N) for the regional mussel watch stations located in Sinclair Inlet, Dyes Inlet, Port Orchard Passage, Rich Passage, Agate Passage, Liberty Bay, and Keyport Lagoon. Indigenous bivalves were collected from a small boat and/or from along the shoreline, measured, composited, and analyzed for a suite of trace metals and organic contaminants. The trace metals included silver, arsenic, cadmium, chromium, copper, mercury, nickel, lead, and zinc. The organic contaminants included the list of NOAA Status and Trends 20 polychlorinated biphenyls (PCB) congeners and suite of parent and methylated polycyclic aromatic hydrocarbons (PAHs). These chemical residue data provide the first year of the biota ambient monitoring.

  18. Electrical impedance tomography: A new monitoring of regional distribution of lung ventilation (principle of work and clinical application

    Directory of Open Access Journals (Sweden)

    Vuković Rade

    2017-01-01

    Full Text Available Soon after it's discovery in the 1980s, the Electrical Impedance Tomography (EIT, became the topic of interest, primarily regarding its applicability in different diagnostic procedures and monitoring. EIT is a non-invasive procedure, with no additional harmful radiation, which can be used continuously to monitor regional distribution of ventilation, in contrast to the computerized tomography and other diagnostic procedures that have a single image of the respiratory system and its function. Additionally, EIT allows continuous visualization of the lung function at the patient bedside, with an immediate assessment of the respiratory therapeutic maneuvers effects. The results obtained by EIT are complementary to other pulmonary diagnostic procedures, primarily from radiology. In general, EIT provides additional information to the conventional pulmonary monitoring. Crucial to the implementation of lung protective ventilation concept is to determine the ideal alveolar recruitment, which maintains open and functional alveoli during ventilation, meanwhile carrying a minimal risk for lung injury with excessive breathing volume ('over distension'. EIT may be considered as a good guide for optimal adjustment of respiratory support parameters and selection of the ventilation mode. Nowadays, the technical and technological development, hardware and software improvements and experimental validation of the results in animals and volunteers, have enabled practical clinical use of EIT, a useful monitor of regional distribution of lungs ventilation.

  19. Ultrasonic sounding and monitoring of the excavation damaged zone in a soft supported gallery

    International Nuclear Information System (INIS)

    Balland, Cyrille; Souley, Mountaka; Morel, Jacques

    2012-01-01

    Document available in extended abstract form only. Under high in situ stresses and high anisotropic stress ratios, the excavation of underground openings generally causes the creation of a disturbed (EdZ: Excavation disturbed Zone) and/or damaged (EDZ: Excavation Damaged Zone) zone, resulting from the initiation and growth of cracks and fractures and by a redistribution and rearrangement of the initial stresses. Due to the modifications of mechanical and hydro-mechanical properties in the EdZ/EDZ, the latter constitute a potential risk for the efficiency of the geologic and/or engineered barriers. To estimate the performance of a site of radioactive waste storage, it is essential to know the geometry, the extensions of the EdZ/EDZ, the density of cracks, their connectivity and the variations of permeability which can result from it. In particular, their extension depends on numerous factors among which the nature of the rock, the pre-existent fractures and their reactivation, the initial stress field (magnitudes and/or rate of anisotropy), the time, the geometry and the techniques of excavations etc.. In addition, the evolution of EdZ/EDZ properties in the medium term is little or poorly known, particularly under the influence of environmental conditions such as the re-confining by near field rock creep in contact with a rigid structural support or the evolution of hydric conditions (desaturation and re-saturation). Ultrasonic experimentation under the OHZ experiment has been implemented to characterize the EDZ extension and its evolution in time according to the structural support type (soft or rigid) and the environmental conditions present in the laboratory. This study consists of two experimental components: (1) the prior auscultation of the sole and face of the gallery by ultrasonic transmission tomography, (2) the monitoring the EDZ and the analysis of measurable changes in the propagation of ultrasonic waves in the medium term. Mechanical modelling of the

  20. Lung surfactant levels are regulated by Ig-Hepta/GPR116 by monitoring surfactant protein D.

    Directory of Open Access Journals (Sweden)

    Taku Fukuzawa

    Full Text Available Lung surfactant is a complex mixture of lipids and proteins, which is secreted from the alveolar type II epithelial cell and coats the surface of alveoli as a thin layer. It plays a crucial role in the prevention of alveolar collapse through its ability to reduce surface tension. Under normal conditions, surfactant homeostasis is maintained by balancing its release and the uptake by the type II cell for recycling and the internalization by alveolar macrophages for degradation. Little is known about how the surfactant pool is monitored and regulated. Here we show, by an analysis of gene-targeted mice exhibiting massive accumulation of surfactant, that Ig-Hepta/GPR116, an orphan receptor, is expressed on the type II cell and sensing the amount of surfactant by monitoring one of its protein components, surfactant protein D, and its deletion results in a pulmonary alveolar proteinosis and emphysema-like pathology. By a coexpression experiment with Sp-D and the extracellular region of Ig-Hepta/GPR116 followed by immunoprecipitation, we identified Sp-D as the ligand of Ig-Hepta/GPR116. Analyses of surfactant metabolism in Ig-Hepta(+/+ and Ig-Hepta(-/- mice by using radioactive tracers indicated that the Ig-Hepta/GPR116 signaling system exerts attenuating effects on (i balanced synthesis of surfactant lipids and proteins and (ii surfactant secretion, and (iii a stimulating effect on recycling (uptake in response to elevated levels of Sp-D in alveolar space.

  1. Lung

    International Nuclear Information System (INIS)

    DeNardo, G.L.; Blankenship, W.J.; Burdine, J.A. Jr.; DeNardo, S.J.

    1975-01-01

    At present no simple statement can be made relative to the role of radionuclidic lung studies in the pediatric population. It is safe to assume that they will be used with increasing frequency for research and clinical applications because of their sensitivity and ready applicability to the pediatric patient. Methods comparable to those used in adults can be used in children older than 4 years. In younger children, however, a single injection of 133 Xe in solution provides an index of both regional perfusion and ventilation which is easier to accomplish. This method is particularly valuable in infants and neonates because it is rapid, requires no patient cooperation, results in a very low radiation dose, and can be repeated in serial studies. Radionuclidic studies of ventilation and perfusion can be performed in almost all children if the pediatrician and the nuclear medicine specialist have motivation and ingenuity. S []ontaneous pulmonary vascular occlusive disease which occurs in infants and pulmonary emboli in children are easily detected using radionuclides. The pathophysiologic defects of pulmonary agenesis, bronchopulmonary sequestration, and foreign body aspiration may be demonstrated by these techniques. These techniques also appear to be useful in following patients with bronchial asthma, cystic fibrosis, congenital emphysema, and postinfection pulmonary abnormalities. (auth)

  2. Lung clearance index to monitor treatment response in pulmonary exacerbations in preschool children with cystic fibrosis.

    Science.gov (United States)

    Rayment, Jonathan H; Stanojevic, Sanja; Davis, Stephanie D; Retsch-Bogart, George; Ratjen, Felix

    2018-05-01

    Antibiotic treatment for pulmonary symptoms in preschool children with cystic fibrosis (CF) varies among clinicians. The lung clearance index (LCI) is sensitive to early CF lung disease, but its utility to monitor pulmonary exacerbations in young children has not been assessed. We aim to (1) understand how LCI changes during lower respiratory tract symptoms relative to a recent clinically stable measurement, (2) determine whether LCI can identify antibiotic treatment response and (3) compare LCI changes to changes in spirometric indices. LCI and spirometry were measured at quarterly clinic visits over a 12-month period in preschool children with CF. Symptomatic visits were identified and classified as treated or untreated. Treatment response was estimated using propensity score matching methods. 104 symptomatic visits were identified in 78 participants. LCI increased from baseline in both treated (mean relative change +23.8% (95% CI 16.2 to 31.4)) and untreated symptomatic visits (mean relative change +11.2% (95% CI 2.4 to 19.9)). A significant antibiotic treatment effect was observed when LCI was used as the outcome measure (average treatment effect -15.5% (95% CI -25.4 to -5.6)) but not for z-score FEV 1 . LCI significantly deteriorated with pulmonary symptoms relative to baseline and improved with antibiotic treatment. These data suggest that LCI may have a role in the routine clinical care of preschool children with CF. © Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2018. All rights reserved. No commercial use is permitted unless otherwise expressly granted.

  3. Listening panel agreement and characteristics of lung sounds digitally recorded from children aged 1–59 months enrolled in the Pneumonia Etiology Research for Child Health (PERCH) case–control study

    Science.gov (United States)

    Park, Daniel E; Watson, Nora L; Buck, W Chris; Bunthi, Charatdao; Devendra, Akash; Ebruke, Bernard E; Elhilali, Mounya; Emmanouilidou, Dimitra; Garcia-Prats, Anthony J; Githinji, Leah; Hossain, Lokman; Madhi, Shabir A; Moore, David P; Mulindwa, Justin; Olson, Dan; Awori, Juliet O; Vandepitte, Warunee P; Verwey, Charl; West, James E; Knoll, Maria D; O'Brien, Katherine L; Feikin, Daniel R; Hammit, Laura L

    2017-01-01

    Introduction Paediatric lung sound recordings can be systematically assessed, but methodological feasibility and validity is unknown, especially from developing countries. We examined the performance of acoustically interpreting recorded paediatric lung sounds and compared sound characteristics between cases and controls. Methods Pneumonia Etiology Research for Child Health staff in six African and Asian sites recorded lung sounds with a digital stethoscope in cases and controls. Cases aged 1–59 months had WHO severe or very severe pneumonia; age-matched community controls did not. A listening panel assigned examination results of normal, crackle, wheeze, crackle and wheeze or uninterpretable, with adjudication of discordant interpretations. Classifications were recategorised into any crackle, any wheeze or abnormal (any crackle or wheeze) and primary listener agreement (first two listeners) was analysed among interpretable examinations using the prevalence-adjusted, bias-adjusted kappa (PABAK). We examined predictors of disagreement with logistic regression and compared case and control lung sounds with descriptive statistics. Results Primary listeners considered 89.5% of 792 case and 92.4% of 301 control recordings interpretable. Among interpretable recordings, listeners agreed on the presence or absence of any abnormality in 74.9% (PABAK 0.50) of cases and 69.8% (PABAK 0.40) of controls, presence/absence of crackles in 70.6% (PABAK 0.41) of cases and 82.4% (PABAK 0.65) of controls and presence/absence of wheeze in 72.6% (PABAK 0.45) of cases and 73.8% (PABAK 0.48) of controls. Controls, tachypnoea, >3 uninterpretable chest positions, crying, upper airway noises and study site predicted listener disagreement. Among all interpretable examinations, 38.0% of cases and 84.9% of controls were normal (p<0.0001); wheezing was the most common sound (49.9%) in cases. Conclusions Listening panel and case–control data suggests our methodology is feasible, likely valid

  4. Sound algorithms

    OpenAIRE

    De Götzen , Amalia; Mion , Luca; Tache , Olivier

    2007-01-01

    International audience; We call sound algorithms the categories of algorithms that deal with digital sound signal. Sound algorithms appeared in the very infancy of computer. Sound algorithms present strong specificities that are the consequence of two dual considerations: the properties of the digital sound signal itself and its uses, and the properties of auditory perception.

  5. Effectiveness of a simple and real-time baseline shift monitoring system during stereotactic body radiation therapy of lung tumors.

    Science.gov (United States)

    Uchida, Yukihiro; Tachibana, Hidenobu; Kamei, Yoshiyuki; Kashihara, Kenichi

    2017-11-01

    This study aimed to clinically validate a simple real-time baseline shift monitoring system in a prospective study of consecutive patients undergoing stereotactic body radiation therapy (SBRT) of lung tumors, and to investigate baseline shift due to intrafraction motion of the patient's body during lung SBRT. Ten consecutive patients with peripheral lung tumors were treated by SBRT consisting of four fractions of 12 Gy each, with a total dose of 48 Gy. During treatment, each patient's geometric displacement in the anterior-posterior and left-right directions (the baseline shift) was measured using a real-time monitoring webcam system. Displacement between the start and end of treatment was measured using an X-ray fluoroscopic imaging system. The displacement measurements of the two systems were compared, and the measurements of baseline shift acquired by the monitoring system during treatment were analyzed for all patients. There was no significant deviation between the monitoring system and the X-ray imaging system, with the accuracy of measurement being within 1 mm. Measurements using the monitoring system showed that 7 min of treatment generated displacements of more than 1 mm in 50% of the patients. Baseline shift of a patient's body may be measured accurately in real time, using a monitoring system without X-ray exposure. The manubrium of the sternum is a good location for measuring the baseline shift of a patient's body at all times. The real-time monitoring system may be useful for measuring the baseline shift of a patient's body independently of a gating system. Copyright © 2017 Associazione Italiana di Fisica Medica. Published by Elsevier Ltd. All rights reserved.

  6. The Effect of Compartmental Asymmetry on the Monitoring of Pulmonary Mechanics and Lung Volumes.

    Science.gov (United States)

    Keenan, Joseph C; Cortes-Puentes, Gustavo A; Adams, Alexander B; Dries, David J; Marini, John J

    2016-11-01

    Esophageal pressure measurement for computation of transpulmonary pressure (P tp ) has begun to be incorporated into clinical use for evaluating forces across the lungs. Gaps exist in our understanding of how esophageal pressure (and therefore P tp ), a value measured at a single site, responds when respiratory system compartments are asymmetrically affected by whole-lung atelectasis or unilateral injury as well as changes in chest wall compliance. We reasoned that P tp would track with aerated volume changes as estimated by functional residual capacity (FRC) and tidal volume. We examined this hypothesis in the setting of asymmetric lungs and changes in intra-abdominal pressure. This study was conducted in the animal laboratory of a university-affiliated hospital. Models of unilateral atelectasis and unilateral and bilateral lung injury exposed to intra-abdominal hypertension (IAH) in 10 deeply sedated mechanically ventilated swine. Atelectasis was created by balloon occlusion of the left main bronchus. Unilateral lung injury was induced by saline lavage of isolated right lung. Diffuse lung injury was induced by saline lavage of both lungs. The peritoneum was insufflated with air to create a model of pressure-regulated IAH. We measured esophageal pressures, airway pressures, FRC by gas dilution, and oxygenation. FRC was reduced by IAH in normal lungs (P volume in the setting of thoracic asymmetry and changes in intra-abdominal pressure. However, used alone, it cannot distinguish the relative contributions of air-space distention and recruitment of lung units. Copyright © 2016 by Daedalus Enterprises.

  7. Lung cancer risk in the electroplating industry in Lombardy, Italy, using the Italian occupational cancer monitoring (OCCAM) information system.

    Science.gov (United States)

    Panizza, Celestino; Bai, Edoardo; Oddone, Enrico; Scaburri, Alessandra; Massari, Stefania; Modonesi, Carlo; Contiero, Paolo; Marinaccio, Alessandro; Crosignani, Paolo

    2012-01-01

    Occupational Cancer Monitoring (OCCAM) is an Italian organization that monitors occupational cancers, by area and industrial sector, by retrieving cases and employment history from official databases. OCCAM previously estimated a relative risk (RR) of lung cancer of about 1.32 among "metal treatment" workers in Lombardy, northern Italy, potentially exposed to chrome and nickel. In the present study, lung cancer risk was estimated among electroplating workers only. Lombardy electroplating companies were identified from descriptions in Social Security files. Lung cancer risk was evaluated from 2001 to 2008 incident cases identified from hospital discharge records. The RR for lung cancer among electroplating workers was 2.03 (90% CI 1.33-3.10, 18 cases) for men; 3.00 (90% CI 1.38-9.03, 4 cases) for women. Electroplaters had higher risks than "metal treatment" workers. Although the risks were due to past exposure, case histories and recent acute effects indicate a present carcinogenic hazard in some Lombardy electroplating factories. Copyright © 2011 Wiley Periodicals, Inc.

  8. Thoracolumbar movement in sound horses trotting in straight lines in hand and on the lunge and the relationship with hind limb symmetry or asymmetry.

    Science.gov (United States)

    Greve, L; Pfau, T; Dyson, S

    2017-02-01

    Equine movement symmetry is changed when turning, which may induce alterations in thoracolumbosacral kinematics; however, this has not previously been investigated. Our objectives were to document thoracolumbar movement in subjectively sound horses comparing straight lines with circles on both reins and to relate these observations to the objectively determined symmetry/asymmetry of hindlimb gait. Fourteen non-lame horses were assessed prospectively in a non-random, cross-sectional survey. The horses were trotted in straight lines and lunged on both reins and inertial sensor data collected at landmarks: withers, T13 and T18, L3, tubera sacrale, and left and right tubera coxae. Data were processed using published methods; angular motion range of motion (ROM; flexion-extension, axial rotation, lateral bending) and translational ROM (dorsoventral and lateral) and symmetry within each stride were assessed. The dorsoventral movement of the back exhibited a sinusoidal pattern with two oscillations per stride. Circles induced greater asymmetry in dorsoventral movement within each stride (mean ± standard deviation, up to 9 ± 6%) compared with straight lines (up to 6 ± 6%). The greatest amplitude of dorsoventral movement (119 ± 14 mm in straight lines vs. 126 ± 20 mm in circles) occurred at T13. Circles induced greater flexion-extension ROM (>1.3°; P = 0.002), lateral bending (>16°; P 16 mm; P = 0.002) compared with straight lines. Circles induced a movement pattern similar to an inside hindlimb lameness, which was significantly associated with the circle-induced greater asymmetry of dorsoventral movement of the thoracolumbar region (P = 0.03). Moving in a circle induces measurable changes in thoracolumbar movement compared with moving in straight lines, associated with alterations in the hindlimb gait. Copyright © 2017 Elsevier Ltd. All rights reserved.

  9. Ambient Monitoring for Sinclair and Dyes Inlets, Puget Sound, Washington: Chemical Analyses for 2012 Regional Mussel Watch

    Energy Technology Data Exchange (ETDEWEB)

    Brandenberger, Jill M.; Kuo, Li-Jung; Suslick, Carolynn R.; Johnston, Robert K.

    2012-09-01

    Under the Project ENVVEST Final Project Agreement, the Puget Sound Naval Shipyard & Intermediate Maintenance Facility (PSNS&IMF), Environmental Protection Agency (EPA), Washington State Department of Ecology (Ecology), and local stakeholders have worked collaboratively to improve the environmental quality of Sinclair and Dyes Inlets. A regional mussel monitoring program began in 2010 to assess the status and trend of ecological resources, assess the effectiveness of cleanup and pollution control measures, and determine if discharges from all sources are protective of beneficial uses including aquatic life. The program collected indigenous mussels to represent a time-integrated measure of bioavailable metals and organic chemicals present in the water column. This document supplements the 2010 indigenous mussel data with 2012 data to provide two years of data on the chemical residue of mussels present in the inter-tidal regions of Sinclair Inlet, Dyes Inlet, Port Orchard Passage, Rich Passage, Agate Passage, Liberty Bay, and Keyport Lagoon. The 2012 data set added one station at PSNS&IMF and one market samples from Penn Cove. Indigenous mussels were collected from a small boat and/or from along the shoreline, measured, composited, and analyzed for percent lipids, percent moisture, stable isotopes of carbon and nitrogen, and a suite of trace metals and organic contaminants. The trace metals included silver (Ag), arsenic (As), cadmium (Cd), copper (Cu), mercury (Hg), lead (Pb), and zinc (Zn). The organic contaminants included the list of NOAA Status and Trends 20 polychlorinated biphenyls (PCB) congeners and suite of parent and methylated polycyclic aromatic hydrocarbons (PAHs). The average lengths between the 2010 and 2012 data were generally less than 30% relative percent difference (RPD). Generally, the metals concentrations were lower in 2012 than 2010 with some notable exceptions in Sinclair Inlet and Rich Passage where increases in Ag, Hg, Pb, Cu, and Zn exceeded

  10. New perspectives in monitoring lung inflammation: analysis of exhaled breath condensate

    National Research Council Canada - National Science Library

    Montuschi, Paolo

    2005-01-01

    ... diseases might be relevant to differential diagnosis. Given its noninvasiveness, this method might be suitable for longitudinal studies in patients with lung disease, including children. This book provides an introduction to the analysis of exhaled breath condensate. To provide an overview of lung inflammation, basic and clinical pharmacology of leukotrie...

  11. Foley Sounds vs Real Sounds

    DEFF Research Database (Denmark)

    Trento, Stefano; Götzen, Amalia De

    2011-01-01

    This paper is an initial attempt to study the world of sound effects for motion pictures, also known as Foley sounds. Throughout several audio and audio-video tests we have compared both Foley and real sounds originated by an identical action. The main purpose was to evaluate if sound effects...

  12. Accuracy of near-patient vs. inbuilt spirometry for monitoring tidal volumes in an in-vitro paediatric lung model.

    Science.gov (United States)

    Morgenroth, S; Thomas, J; Cannizzaro, V; Weiss, M; Schmidt, A R

    2018-03-01

    Spirometric monitoring provides precise measurement and delivery of tidal volumes within a narrow range, which is essential for lung-protective strategies that aim to reduce morbidity and mortality in mechanically-ventilated patients. Conventional anaesthesia ventilators include inbuilt spirometry to monitor inspiratory and expiratory tidal volumes. The GE Aisys CS 2 anaesthesia ventilator allows additional near-patient spirometry via a sensor interposed between the proximal end of the tracheal tube and the respiratory tubing. Near-patient and inbuilt spirometry of two different GE Aisys CS 2 anaesthesia ventilators were compared in an in-vitro study. Assessments were made of accuracy and variability in inspiratory and expiratory tidal volume measurements during ventilation of six simulated paediatric lung models using the ASL 5000 test lung. A total of 9240 breaths were recorded and analysed. Differences between inspiratory tidal volumes measured with near-patient and inbuilt spirometry were most significant in the newborn setting (p tidal volume measurements with near-patient spirometry were consistently more accurate than with inbuilt spirometry for all lung models (p tidal volumes decreased with increasing tidal volumes, and was smaller with near-patient than with inbuilt spirometry. The variability in measured tidal volumes was higher during expiration, especially with inbuilt spirometry. In conclusion, the present in-vitro study shows that measurements with near-patient spirometry are more accurate and less variable than with inbuilt spirometry. Differences between measurement methods were most significant in the smallest patients. We therefore recommend near-patient spirometry, especially for neonatal and paediatric patients. © 2018 The Association of Anaesthetists of Great Britain and Ireland.

  13. Imagining Sound

    DEFF Research Database (Denmark)

    Grimshaw, Mark; Garner, Tom Alexander

    2014-01-01

    We make the case in this essay that sound that is imagined is both a perception and as much a sound as that perceived through external stimulation. To argue this, we look at the evidence from auditory science, neuroscience, and philosophy, briefly present some new conceptual thinking on sound...... that accounts for this view, and then use this to look at what the future might hold in the context of imagining sound and developing technology....

  14. SU-E-T-551: Monitor Unit Optimization in Stereotactic Body Radiation Therapy for Stage I Lung Cancer

    International Nuclear Information System (INIS)

    Huang, B-T; Lu, J-Y

    2015-01-01

    Purpose: The study aims to reduce the monitor units (MUs) in the stereotactic body radiation therapy (SBRT) treatment for lung cancer by adjusting the optimizing parameters. Methods: Fourteen patients suffered from stage I Non-Small Cell Lung Cancer (NSCLC) were enrolled. Three groups of parameters were adjusted to investigate their effects on MU numbers and organs at risk (OARs) sparing: (1) the upper objective of planning target volume (UOPTV); (2) strength setting in the MU constraining objective; (3) max MU setting in the MU constraining objective. Results: We found that the parameters in the optimizer influenced the MU numbers in a priority, strength and max MU dependent manner. MU numbers showed a decreasing trend with the UOPTV increasing. MU numbers with low, medium and high priority for the UOPTV were 428±54, 312±48 and 258±31 MU/Gy, respectively. High priority for UOPTV also spared the heart, cord and lung while maintaining comparable PTV coverage than the low and medium priority group. It was observed that MU numbers tended to decrease with the strength increasing and max MU setting decreasing. With maximum strength, the MU numbers reached its minimum while maintaining comparable or improved dose to the normal tissues. It was also found that the MU numbers continued to decline at 85% and 75% max MU setting but no longer to decrease at 50% and 25%. Combined with high priority for UOPTV and MU constraining objectives, the MU numbers can be decreased as low as 223±26 MU/Gy. Conclusion:: The priority of UOPTV, MU constraining objective in the optimizer impact on the MU numbers in SBRT treatment for lung cancer. Giving high priority to the UOPTV, setting the strength to maximum value and the max MU to 50% in the MU objective achieves the lowest MU numbers while maintaining comparable or improved OAR sparing

  15. The value of 99Tcm-HSA in monitoring acute lung injury induced by lipopolysaccharide in rats

    International Nuclear Information System (INIS)

    Fu Zhanli; Zhang Chunli; Wang Rongfu; Zhang Shengsuo; Xue Yun

    2005-01-01

    To evaluate the value of 99 Tc m labeled human serum albumin ( 99 Tc m -HSA) in monitoring acute lung injury (ALI) induced by lipopolysaccharide (LPS) in rats, twenty adult Wistar rats are given 99 Tc m -HSA intravenously, and are randomly divided into four groups 30 min later. The control and LPS group are given intravenous injection of 0.9% saline and LPS 8 mg/kg respectively. The ketamine and aminoguanidine group are given intraperitoneal injection of ketamine 4 mg/kg and aminoguanidine 20 mg/kg respectively just 30 min after administration of LPS 8 mg/kg. All of the four group rats are killed by blood letting at 3 h post-injection of 99 Tc m -HSA. Pulmonary permeability index (PPI) and the ratio of lung wet weight and dry weight (W/D) is calculated. The results of PPI and W/D in control and LPS group are 95.58 ± 11.32 and 5.38 ± 0.24, 6.61 ± 0.18 and 4.19 ± 0.11, respectively. The PPI and W/D in LPS group are much higher than that in the control group (P 0.05). So 99 tc m -HSA is an effective tracer in monitoring ALI induced by LPS in rats. (authors)

  16. Annual Report: 2010-2011 Storm Season Sampling For NON-DRY DOCK STORMWATER MONITORING FOR PUGET SOUND NAVAL SHIPYARD, BREMERTON, WA

    Energy Technology Data Exchange (ETDEWEB)

    Brandenberger, Jill M.; Metallo, David; Johnston, Robert K.; Gebhardt, Christine; Hsu, Larry

    2012-09-01

    This interim report summarizes the stormwater monitoring conducted for non-dry dock outfalls in both the confined industrial area and the residential areas of Naval Base Kitsap within the Puget Sound Naval Shipyard (referred to as the Shipyard). This includes the collection, analyses, and descriptive statistics for stormwater sampling conducted from November 2010 through April 2011. Seven stormwater basins within the Shipyard were sampled during at least three storm events to characterize non-dry dock stormwater discharges at selected stormwater drains located within the facility. This serves as the Phase I component of the project and Phase II is planned for the 2011-2012 storm season. These data will assist the Navy, USEPA, Ecology and other stakeholders in understanding the nature and condition of stormwater discharges from the Shipyard and inform the permitting process for new outfall discharges. The data from Phase I was compiled with current stormwater data available from the Shipyard, Sinclair/Dyes Inlet watershed, and Puget Sound in order to support technical investigations for the Draft NPDES permit. The permit would require storm event sampling at selected stormwater drains located within the Shipyard. However, the data must be considered on multiple scales to truly understand potential impairments to beneficial uses within Sinclair and Dyes Inlets.

  17. Unsound Sound

    DEFF Research Database (Denmark)

    Knakkergaard, Martin

    2016-01-01

    This article discusses the change in premise that digitally produced sound brings about and how digital technologies more generally have changed our relationship to the musical artifact, not simply in degree but in kind. It demonstrates how our acoustical conceptions are thoroughly challenged...... by the digital production of sound and, by questioning the ontological basis for digital sound, turns our understanding of the core term substance upside down....

  18. Sound Absorbers

    Science.gov (United States)

    Fuchs, H. V.; Möser, M.

    Sound absorption indicates the transformation of sound energy into heat. It is, for instance, employed to design the acoustics in rooms. The noise emitted by machinery and plants shall be reduced before arriving at a workplace; auditoria such as lecture rooms or concert halls require a certain reverberation time. Such design goals are realised by installing absorbing components at the walls with well-defined absorption characteristics, which are adjusted for corresponding demands. Sound absorbers also play an important role in acoustic capsules, ducts and screens to avoid sound immission from noise intensive environments into the neighbourhood.

  19. Sound as Popular Culture

    DEFF Research Database (Denmark)

    The wide-ranging texts in this book take as their premise the idea that sound is a subject through which popular culture can be analyzed in an innovative way. From an infant’s gurgles over a baby monitor to the roar of the crowd in a stadium to the sub-bass frequencies produced by sound systems...... in the disco era, sound—not necessarily aestheticized as music—is inextricably part of the many domains of popular culture. Expanding the view taken by many scholars of cultural studies, the contributors consider cultural practices concerning sound not merely as semiotic or signifying processes but as material......, physical, perceptual, and sensory processes that integrate a multitude of cultural traditions and forms of knowledge. The chapters discuss conceptual issues as well as terminologies and research methods; analyze historical and contemporary case studies of listening in various sound cultures; and consider...

  20. Usefulness of SCC-antigen for diagnosis and monitoring recurrence and effectiveness of therapies of squamous cell carcinoma of the lung

    International Nuclear Information System (INIS)

    Mino, Naoko; Iio, Atsushi; Ata, Mariko; Murase, Kenya; Kataoka, Masaaki; Ito, Hisao; Ishine, Masahiro; Kawamura, Masashi; Hamamoto, Ken

    1987-01-01

    The serum levels of SCC antigen (squamous cell carcinoma related antigen) were measured in 111 patients with primary lung cancer to assess its clinical usefulness for diagnosis of squamous cell carcinoma and for monitoring recurrence and effectiveness of therapies. Serum SCC antigen level in patients with squamous cell carcinoma of the lung was 5.9 ± 10.4 ng/ml, which was high (p < 0.05) compared with those in normal controls (1.6 ± 0.5 ng/ml), patients with other types of lung cancer (2.4 ± 2.9 ng/ml) or benign disease (1.8 ± 1.1 ng/ml). Studies at various clinical stages of squamous cell carcinoma of the lung showed, however, that the SCC antigen levels were high only in the advanced stages (III and IV), whereas not so high in the earlier stages. These results confirmed that SCC antigen is a relatively specific marker to squamous cell carcinoma in the lung, as reported in the uterine cervix and the esophagus. The SCC antigen levels decreased after operation and more markedly after radiotherapy in dose-dependent manner, corresponding to the reduction of the tumor size. On the other hand, the SCC antigen levels were extremely high in the recurrence. It was concluded that SCC antigen is a useful marker for monitoring recurrence or effectiveness of the therapies of SCC of the lung, although not so for its early diagnosis. (author)

  1. The reliability of lung crackle characteristics in cystic fibrosis and bronchiectasis patients in a clinical setting

    International Nuclear Information System (INIS)

    Marques, Alda; Bruton, Anne; Barney, Anna

    2009-01-01

    Lung sounds provide useful information for assessing and monitoring respiratory patients, but standard auscultation is subjective. Computer aided lung sound analysis (CALSA) enables the quantification and characterisation of added lung sounds (e.g. crackles). At present, little is known about the reliability of these sound characteristics. Therefore, the aim of this study was to explore the reliability of crackle initial deflection width (IDW) and two-cycle deflection (2CD) in a clinical population. Fifty-four subjects (37 bronchiectasis, 17 cystic fibrosis) were recruited from out-patient clinics. Three repeated lung sound recordings were taken at seven anatomical sites with a digital stethoscope connected to a laptop computer. The intra-subject reliability of crackle IDW and 2CD was found to be 'good' to 'excellent', estimated by the analysis of variance, intraclass correlation coefficient (IDW 0.76;0.85, 2CD 0.83;0.94), Bland and Altman 95% limits of agreement (IDW −0.50;0.47 ms, 2CD −2.12;1.87 ms) and smallest real difference (IDW 0.30;0.66 ms, 2CD 1.57;2.42 ms). Crackle 2CD was found to be more reliable than IDW. It is concluded that crackle IDW and 2CD characterized by CALSA have good test–retest reliability. This technique requires further evaluation since CALSA has potential to diagnose or monitor respiratory conditions, and provide an objective physiological measure for respiratory interventions

  2. Effects of staff training and electronic event monitoring on long-term adherence to lung-protective ventilation recommendations.

    Science.gov (United States)

    Castellanos, Ixchel; Martin, Marcus; Kraus, Stefan; Bürkle, Thomas; Prokosch, Hans-Ulrich; Schüttler, Jürgen; Toddenroth, Dennis

    2018-02-01

    To investigate long-term effects of staff training and electronic clinical decision support (CDS) on adherence to lung-protective ventilation recommendations. In 2012, group instructions and workshops at two surgical intensive care units (ICUs) started, focusing on standardized protocols for mechanical ventilation and volutrauma prevention. Subsequently implemented CDS functions continuously monitor ventilation parameters, and from 2015 triggered graphical notifications when tidal volume (V T ) violated individual thresholds. To estimate the effects of these educational and technical interventions, we retrospectively analyzed nine years of V T records from routine care. As outcome measures, we calculated relative frequencies of settings that conform to recommendations, case-specific mean excess V T , and total ICU survival. Assessing 571,478 V T records from 10,241 ICU cases indicated that adherence during pressure-controlled ventilation improved significantly after both interventions; the share of conforming V T records increased from 61.6% to 83.0% and then 86.0%. Despite increasing case severity, ICU survival remained nearly constant over time. Staff training effectively improves adherence to lung-protective ventilation strategies. The observed CDS effect seemed less pronounced, although it can easily be adapted to new recommendations. Both interventions, which futures studies could deploy in combination, promise to improve the precision of mechanical ventilation. Copyright © 2017 The Authors. Published by Elsevier Inc. All rights reserved.

  3. Evaluation of parameters associated with monitoring in vivo of uranium isotopes in the lungs

    International Nuclear Information System (INIS)

    Juppa, Silvia P.; Lucena, Eder A.; Dantas, Bernardo M.; Dantas, Ana Leticia A.

    2013-01-01

    The objective of this study is to evaluate the parameters associated with the technique of monitoring individuals exposed to uranium isotopes, aiming to optimize the technique and reduced uncertainties associated

  4. Sound generator

    NARCIS (Netherlands)

    Berkhoff, Arthur P.

    2008-01-01

    A sound generator, particularly a loudspeaker, configured to emit sound, comprising a rigid element (2) enclosing a plurality of air compartments (3), wherein the rigid element (2) has a back side (B) comprising apertures (4), and a front side (F) that is closed, wherein the generator is provided

  5. Sound generator

    NARCIS (Netherlands)

    Berkhoff, Arthur P.

    2010-01-01

    A sound generator, particularly a loudspeaker, configured to emit sound, comprising a rigid element (2) enclosing a plurality of air compartments (3), wherein the rigid element (2) has a back side (B) comprising apertures (4), and a front side (F) that is closed, wherein the generator is provided

  6. Sound generator

    NARCIS (Netherlands)

    Berkhoff, Arthur P.

    2007-01-01

    A sound generator, particularly a loudspeaker, configured to emit sound, comprising a rigid element (2) enclosing a plurality of air compartments (3), wherein the rigid element (2) has a back side (B) comprising apertures (4), and a front side (F) that is closed, wherein the generator is provided

  7. Seabed sediment classification for monitoring underwater nourishments using time series of multi-beam echo-soundings

    Science.gov (United States)

    Gaida, T. C.; Snellen, M.; van Dijk, T. A. G. P.; Simons, D. G.

    2017-12-01

    Coastal erosion induced by natural processes, such as wind, waves, tidal currents, or human interferences endangers human beings, infrastructure, fauna and flora at the oceans and rivers all over the world. In The Netherlands, in particular the North Sea islands are strongly affected by sediment erosion. To protect and stabilize the coastline, beach and shoreface nourishments are frequently performed. Thereby, sediment reservoirs are created that replace the eroded sediments. Increasing the long-term efficiency of coastal protection requires monitoring of the temporal and spatial development of the coastal nourishments. Multi-beam echo-sounders (MBES) allow for detailed and comprehensive investigations of the seabed composition and structure. To investigate the potential of using MBES for monitoring nourishments in a tidal inlet, four MBES surveys per year are carried out at the Dutch Wadden island Ameland. A pre-nourishment MBES survey was performed in April 2017 and the subsequent post-nourishment survey will take place in September 2017. Both surveys are equipped with a Kongsberg EM 2040C dual-head MBES and are supported with extensive grab sampling. In this study the use of MBES backscatter and bathymetry data are considered as an approach for monitoring coastal nourishments. The aim is to develop a monitoring procedure that allows for comparing MBES data taken during different surveys, i.e., with variations in environmental conditions, MBES characteristics and acquisition procedures. Different unsupervised and supervised acoustic seafloor classification techniques are applied to the processed MBES data to classify the seabed sediments. The analysis of the pre-nourishment MBES data indicates that the backscatter and consequently the classification are highly driven by the abundancy of shell fragments. These results will be used as a baseline to investigate the accumulation of the underwater nourishments. Independent grab samples will be used to select the

  8. Vascular and lung function related to ultrafine and fine particles exposure assessed by personal and indoor monitoring: a cross-sectional study

    DEFF Research Database (Denmark)

    Olsen, Yulia; Karottki, Dorina Gabriela; Jensen, Ditte Marie

    2014-01-01

    -related effects. Methods: Associations between vascular and lung function, inflammation markers and exposure in terms of particle number concentration (PNC; d = 10-300 nm) were studied in a cross-sectional design with personal and home indoor monitoring in the Western Copenhagen Area, Denmark. During 48-h, PNC...... and PM2.5 were monitored in living rooms of 60 homes with 81 non-smoking subjects (30-75 years old), 59 of whom carried personal monitors both when at home and away from home. We measured lung function in terms of the FEV1/FVC ratio, microvascular function (MVF) and pulse amplitude by digital artery...... tonometry, blood pressure and biomarkers of inflammation including C-reactive protein, and leukocyte counts with subdivision in neutrophils, eosinophils, monocytes, and lymphocytes in blood. Results: PNC from personal and stationary home monitoring showed weak correlation (r = 0.15, p = 0.24). Personal UFP...

  9. Radiotherapy of lung cancer: the inspiration breath hold with a spirometric monitoring

    International Nuclear Information System (INIS)

    Garcia, R.; Oozeer, R.; Le Thanh, H.; Chastel, D.; Doyen, J.C.; Chauvet, B.; Reboul, F.

    2002-01-01

    A CT acquisition during a free breathing examination generates images of poor quality. It creates an uncertainty on the reconstructed gross tumour volume and dose distribution. The aim of this study is to test the feasibility of a breath hold method applied in all preparation and treatment days. Five patients received a thoracic radiotherapy with the benefit of this procedure. The breathing of the patient was measured with a spirometer. The patient was coached to reproduce a constant level of breath-hold in a deep inspiration. Video glasses helped the patients to fix the breath-hold at the reference level. The patients followed the coaching during preparation and treatment, without any difficulty. The better quality of the CT reconstructed images resulted in an easier contouring. No movements of the gross tumour volume lead to a better coverage. The deep breath hold decreased the volume of irradiated lung. This method improves the reproducibility of the thoracic irradiation. The decrease of irradiated lung volume offers prospects in dose escalation and intensity modulation radiotherapy. (authors)

  10. Use of PET to monitor the response of lung cancer to radiation treatment

    International Nuclear Information System (INIS)

    Erdi, Y.E.; Humm, J.L.; Erdi, A.K.; Yorke, E.D.; Macapinlac, H.; Larson, S.M.; Rosenzweig, K.E.

    2000-01-01

    Approximately 170,000 people are diagnosed with lung cancer in the United States each year. Many of these patients receive external beam radiation for treatment. Fluorine-18 2-fluoro-2-deoxy-d-glucose positron emission tomography (FDG PET) is increasingly being used in evaluating non-small cell lung cancer and may be of clinical utility in assessing response to treatment. In this report, we present FDG PET images and data from two patients who were followed with a total of eight and seven serial FDG PET scans, respectively, through the entire course of their radiation therapy. Changes in several potential response parameters are shown versus time, including lesion volume (V FDG ) by PET, SUV av , SUV max , and total lesion glycolysis (TLG) during the course of radiotherapy. The response parameters for patient 1 demonstrated a progressive decrease; however, the response parameters for patient 2 showed an initial decrease followed by an increase. The data presented here may suggest that the outcome of radiation therapy can be predicted by PET imaging, but this observation requires a study of additional patients. (orig.)

  11. Development and evaluation of a technique for in vivo monitoring of 60Co in the lungs

    International Nuclear Information System (INIS)

    Mello, J.Q. de; Lucena, E.A.; Dantas, A.L.A.; Dantas, B.M.

    2015-01-01

    60 Co is a fission product of 235 U and represents a risk of internal exposure of workers in nuclear power plants, especially those involved in the maintenance of potentially contaminated parts and equipment. The control of 60 Co intake by inhalation can be performed through in vivo monitoring. This work describes the evaluation of a technique through the minimum detectable activity and the corresponding minimum detectable effective doses, based on biokinetic and dosimetric models of 60 Co in the human body. The results allow to state that the technique is suitable either for monitoring of occupational exposures or evaluation of accidental intakes. (author)

  12. Sound Zones

    DEFF Research Database (Denmark)

    Møller, Martin Bo; Olsen, Martin

    2017-01-01

    Sound zones, i.e. spatially confined regions of individual audio content, can be created by appropriate filtering of the desired audio signals reproduced by an array of loudspeakers. The challenge of designing filters for sound zones is twofold: First, the filtered responses should generate...... an acoustic separation between the control regions. Secondly, the pre- and post-ringing as well as spectral deterioration introduced by the filters should be minimized. The tradeoff between acoustic separation and filter ringing is the focus of this paper. A weighted L2-norm penalty is introduced in the sound...

  13. Sound intensity

    DEFF Research Database (Denmark)

    Crocker, Malcolm J.; Jacobsen, Finn

    1998-01-01

    This chapter is an overview, intended for readers with no special knowledge about this particular topic. The chapter deals with all aspects of sound intensity and its measurement from the fundamental theoretical background to practical applications of the measurement technique.......This chapter is an overview, intended for readers with no special knowledge about this particular topic. The chapter deals with all aspects of sound intensity and its measurement from the fundamental theoretical background to practical applications of the measurement technique....

  14. Sound Intensity

    DEFF Research Database (Denmark)

    Crocker, M.J.; Jacobsen, Finn

    1997-01-01

    This chapter is an overview, intended for readers with no special knowledge about this particular topic. The chapter deals with all aspects of sound intensity and its measurement from the fundamental theoretical background to practical applications of the measurement technique.......This chapter is an overview, intended for readers with no special knowledge about this particular topic. The chapter deals with all aspects of sound intensity and its measurement from the fundamental theoretical background to practical applications of the measurement technique....

  15. Assessment of the applicability of AWJ technique for dismantling the reactor of Fugen. Performance of underwater-cutting thick plate and testing of sound-based monitoring for underwater-cutting process

    International Nuclear Information System (INIS)

    Maruyama, Shin-ichiro; Nishio, Shin-ichi

    2010-01-01

    The reactor of Fugen is characterized by its double-walled pressure tube construction that is composed of pressure tubes and calandria tubes. The reactor dismantlement has been planning on dismantling it under water and the abrasive water jet (AWJ) underwater-cutting method is chosen as an option among simultaneous double tubes cutting technologies. For assessing the applicability of the AWJ cutting technology, a thick plate was cut under water by the small AWJ cutting machine. In addition, since cutting causes muddiness in water, cutting was monitored by the sound-based monitoring system which was adopted as a secondary cutting monitoring method. As a results, it was demonstrated that one-phase cutting was possible under water for a stainless-steel plate with 150mm thickness and that the relationship between cutting depth and capable cutting speed could be predictable. As for the sound-based cutting monitoring, the predictability whether or not cutting would be successful was verified by checking the change of sounds level. (author)

  16. The Agreement between Auscultation and Lung Ultrasound in Hemodialysis Patients: The LUST Study.

    Science.gov (United States)

    Torino, Claudia; Gargani, Luna; Sicari, Rosa; Letachowicz, Krzysztof; Ekart, Robert; Fliser, Danilo; Covic, Adrian; Siamopoulos, Kostas; Stavroulopoulos, Aristeidis; Massy, Ziad A; Fiaccadori, Enrico; Caiazza, Alberto; Bachelet, Thomas; Slotki, Itzchak; Martinez-Castelao, Alberto; Coudert-Krier, Marie-Jeanne; Rossignol, Patrick; Gueler, Faikah; Hannedouche, Thierry; Panichi, Vincenzo; Wiecek, Andrzej; Pontoriero, Giuseppe; Sarafidis, Pantelis; Klinger, Marian; Hojs, Radovan; Seiler-Mussler, Sarah; Lizzi, Fabio; Siriopol, Dimitrie; Balafa, Olga; Shavit, Linda; Tripepi, Rocco; Mallamaci, Francesca; Tripepi, Giovanni; Picano, Eugenio; London, Gérard Michel; Zoccali, Carmine

    2016-11-07

    Accumulation of fluid in the lung is the most concerning sequela of volume expansion in patients with ESRD. Lung auscultation is recommended to detect and monitor pulmonary congestion, but its reliability in ESRD is unknown. In a subproject of the ongoing Lung Water by Ultra-Sound Guided Treatment to Prevent Death and Cardiovascular Complications in High Risk ESRD Patients with Cardiomyopathy Trial, we compared a lung ultrasound-guided ultrafiltration prescription policy versus standard care in high-risk patients on hemodialysis. The reliability of peripheral edema was tested as well. This study was on the basis of 1106 pre- and postdialysis lung ultrasound studies (in 79 patients) simultaneous with standardized lung auscultation (crackles at the lung bases) and quantification of peripheral edema. Lung congestion by crackles, edema, or a combination thereof poorly reflected the severity of congestion as detected by ultrasound B lines in various analyses, including standard regression analysis weighting for repeated measures in individual patients (shared variance of 12% and 4% for crackles and edema, respectively) and κ-statistics (κ ranging from 0.00 to 0.16). In general, auscultation had very low discriminatory power for the diagnosis of mild (area under the receiver operating curve =0.61), moderate (area under the receiver operating curve =0.65), and severe (area under the receiver operating curve =0.68) lung congestion, and the same was true for peripheral edema (receiver operating curve =0.56 or lower) and the combination of the two physical signs. Lung crackles, either alone or combined with peripheral edema, very poorly reflect interstitial lung edema in patients with ESRD. These findings reinforce the rationale underlying the Lung Water by Ultra-Sound Guided Treatment to Prevent Death and Cardiovascular Complications in High Risk ESRD Patients with Cardiomyopathy Trial, a trial adopting ultrasound B lines as an instrument to guide interventions aimed at

  17. Fluid Sounds

    DEFF Research Database (Denmark)

    Explorations and analysis of soundscapes have, since Canadian R. Murray Schafer's work during the early 1970's, developed into various established research - and artistic disciplines. The interest in sonic environments is today present within a broad range of contemporary art projects and in arch......Explorations and analysis of soundscapes have, since Canadian R. Murray Schafer's work during the early 1970's, developed into various established research - and artistic disciplines. The interest in sonic environments is today present within a broad range of contemporary art projects...... and in architectural design. Aesthetics, psychoacoustics, perception, and cognition are all present in this expanding field embracing such categories as soundscape composition, sound art, sonic art, sound design, sound studies and auditory culture. Of greatest significance to the overall field is the investigation...

  18. Sound Settlements

    DEFF Research Database (Denmark)

    Mortensen, Peder Duelund; Hornyanszky, Elisabeth Dalholm; Larsen, Jacob Norvig

    2013-01-01

    Præsentation af projektresultater fra Interreg forskningen Sound Settlements om udvikling af bæredygtighed i det almene boligbyggerier i København, Malmø, Helsingborg og Lund samt europæiske eksempler på best practice......Præsentation af projektresultater fra Interreg forskningen Sound Settlements om udvikling af bæredygtighed i det almene boligbyggerier i København, Malmø, Helsingborg og Lund samt europæiske eksempler på best practice...

  19. Nuclear sound

    International Nuclear Information System (INIS)

    Wambach, J.

    1991-01-01

    Nuclei, like more familiar mechanical systems, undergo simple vibrational motion. Among these vibrations, sound modes are of particular interest since they reveal important information on the effective interactions among the constituents and, through extrapolation, on the bulk behaviour of nuclear and neutron matter. Sound wave propagation in nuclei shows strong quantum effects familiar from other quantum systems. Microscopic theory suggests that the restoring forces are caused by the complex structure of the many-Fermion wavefunction and, in some cases, have no classical analogue. The damping of the vibrational amplitude is strongly influenced by phase coherence among the particles participating in the motion. (author)

  20. Heart Sound Localization and Reduction in Tracheal Sounds by Gabor Time-Frequency Masking

    OpenAIRE

    SAATCI, Esra; Akan, Aydın

    2018-01-01

    Background and aim: Respiratorysounds, i.e. tracheal and lung sounds, have been of great interest due to theirdiagnostic values as well as the potential of their use in the estimation ofthe respiratory dynamics (mainly airflow). Thus the aim of the study is topresent a new method to filter the heart sound interference from the trachealsounds. Materials and methods: Trachealsounds and airflow signals were collected by using an accelerometer from 10 healthysubjects. Tracheal sounds were then pr...

  1. Sound Settlements

    DEFF Research Database (Denmark)

    Mortensen, Peder Duelund; Hornyanszky, Elisabeth Dalholm; Larsen, Jacob Norvig

    2013-01-01

    Præsentation af projektresultater fra Interreg forskningen Sound Settlements om udvikling af bæredygtighed i det almene boligbyggerier i København, Malmø, Helsingborg og Lund samt europæiske eksempler på best practice...

  2. Second Sound

    Indian Academy of Sciences (India)

    Home; Journals; Resonance – Journal of Science Education; Volume 4; Issue 6. Second Sound - The Role of Elastic Waves. R Srinivasan. General Article Volume 4 Issue 6 June 1999 pp 15-19. Fulltext. Click here to view fulltext PDF. Permanent link: https://www.ias.ac.in/article/fulltext/reso/004/06/0015-0019 ...

  3. Sound pressure level tools design used in occupational health by means of Labview software

    Directory of Open Access Journals (Sweden)

    Farhad Forouharmajd

    2015-01-01

    Conclusion: LabVIEW programming capabilities in the field of sound can be referred to the measurement of sound, frequency analysis, and sound control that actually the software acts like a sound level meter and sound analyzer. According to the mentioned features, we can use this software to analyze and process sound and vibration as a monitoring system.

  4. PREFACE: Aerodynamic sound Aerodynamic sound

    Science.gov (United States)

    Akishita, Sadao

    2010-02-01

    The modern theory of aerodynamic sound originates from Lighthill's two papers in 1952 and 1954, as is well known. I have heard that Lighthill was motivated in writing the papers by the jet-noise emitted by the newly commercialized jet-engined airplanes at that time. The technology of aerodynamic sound is destined for environmental problems. Therefore the theory should always be applied to newly emerged public nuisances. This issue of Fluid Dynamics Research (FDR) reflects problems of environmental sound in present Japanese technology. The Japanese community studying aerodynamic sound has held an annual symposium since 29 years ago when the late Professor S Kotake and Professor S Kaji of Teikyo University organized the symposium. Most of the Japanese authors in this issue are members of the annual symposium. I should note the contribution of the two professors cited above in establishing the Japanese community of aerodynamic sound research. It is my pleasure to present the publication in this issue of ten papers discussed at the annual symposium. I would like to express many thanks to the Editorial Board of FDR for giving us the chance to contribute these papers. We have a review paper by T Suzuki on the study of jet noise, which continues to be important nowadays, and is expected to reform the theoretical model of generating mechanisms. Professor M S Howe and R S McGowan contribute an analytical paper, a valuable study in today's fluid dynamics research. They apply hydrodynamics to solve the compressible flow generated in the vocal cords of the human body. Experimental study continues to be the main methodology in aerodynamic sound, and it is expected to explore new horizons. H Fujita's study on the Aeolian tone provides a new viewpoint on major, longstanding sound problems. The paper by M Nishimura and T Goto on textile fabrics describes new technology for the effective reduction of bluff-body noise. The paper by T Sueki et al also reports new technology for the

  5. Personalized biomarkers to monitor disease progression in advanced non-small-cell lung cancer patients treated with icotinib.

    Science.gov (United States)

    Song, Gaoguang; Liu, Yujie; Wang, Yanying; Ren, Guanjun; Guo, Shuai; Ren, Junling; Zhang, Li; Li, Zhili

    2015-02-02

    Disease-specific humoral immune response-related protein complexes in blood are associated with disease progression. Thirty-one patients with stage IIIB and IV non-small-cell lung cancer (NSCLC) were administered with oral dose of icotinib hydrochloride (150 mg twice daily or 125 mg 3 times daily) for a 28-continuous-day cycle until diseases progressed or unacceptable toxicity occurred. The levels of immunoinflammation-related protein complexes (IIRPCs) in a series of plasma samples from 31 NSCLC patients treated with icotinib hydrochloride were determined by an optimized native polyacrylamide gel electrophoresis. Three characteristic patterns of the IIRPCs, named as patterns a, b, and c, respectively, were detected in plasma samples from 31 patients. Prior to the treatment, there were 18 patients in pattern a consisting of 5 IIRPCs, 9 in pattern b consisting of six IIRPCs, and 4 in pattern c without the IIRPCs. The levels of the IIRPCs in 27 patients were quantified. Our results indicate that the time length of humoral immune and inflammation response (TLHIIR) was closely associated with disease progression, and the median TLHIIR was 22.0 weeks, 95% confidence interval: 16.2 to 33.0 weeks, with a lead time of median 11 weeks relative to clinical imaging evidence confirmed by computed tomography or magnetic resonance imaging (the median progression-free survival, 34.0 weeks, 95% confidence interval: 27.9 to 49.0 weeks). The complex relationships between humoral immune response, acquired resistance, and disease progression existed. Personalized IIRPCs could be indicators to monitor the disease progression. Copyright © 2014 Elsevier B.V. All rights reserved.

  6. Sound Visualisation

    OpenAIRE

    Dolenc, Peter

    2013-01-01

    This thesis contains a description of a construction of subwoofer case that has an extra functionality of being able to produce special visual effects and display visualizations that match the currently playing sound. For this reason, multiple lighting elements made out of LED (Light Emitting Diode) diodes were installed onto the subwoofer case. The lighting elements are controlled by dedicated software that was also developed. The software runs on STM32F4-Discovery evaluation board inside a ...

  7. Volume-monitored chest CT: a simplified method for obtaining motion-free images near full inspiratory and end expiratory lung volumes

    Energy Technology Data Exchange (ETDEWEB)

    Mueller, Kathryn S. [The Ohio State University College of Medicine, Columbus, OH (United States); Long, Frederick R. [Nationwide Children' s Hospital, The Children' s Radiological Institute, Columbus, OH (United States); Flucke, Robert L. [Nationwide Children' s Hospital, Department of Pulmonary Medicine, Columbus, OH (United States); Castile, Robert G. [The Research Institute at Nationwide Children' s Hospital, Center for Perinatal Research, Columbus, OH (United States)

    2010-10-15

    Lung inflation and respiratory motion during chest CT affect diagnostic accuracy and reproducibility. To describe a simple volume-monitored (VM) method for performing reproducible, motion-free full inspiratory and end expiratory chest CT examinations in children. Fifty-two children with cystic fibrosis (mean age 8.8 {+-} 2.2 years) underwent pulmonary function tests and inspiratory and expiratory VM-CT scans (1.25-mm slices, 80-120 kVp, 16-40 mAs) according to an IRB-approved protocol. The VM-CT technique utilizes instruction from a respiratory therapist, a portable spirometer and real-time documentation of lung volume on a computer. CT image quality was evaluated for achievement of targeted lung-volume levels and for respiratory motion. Children achieved 95% of vital capacity during full inspiratory imaging. For end expiratory scans, 92% were at or below the child's end expiratory level. Two expiratory exams were judged to be at suboptimal volumes. Two inspiratory (4%) and three expiratory (6%) exams showed respiratory motion. Overall, 94% of scans were performed at optimal volumes without respiratory motion. The VM-CT technique is a simple, feasible method in children as young as 4 years to achieve reproducible high-quality full inspiratory and end expiratory lung CT images. (orig.)

  8. TH-CD-207A-05: Lung Surface Deformation Vector Fields Prediction by Monitoring Respiratory Surrogate Signals

    International Nuclear Information System (INIS)

    Nasehi Tehrani, J; Wang, J; McEwan, A

    2016-01-01

    Purpose: In this study, we developed and evaluated a method for predicting lung surface deformation vector fields (SDVFs) based on surrogate signals such as chest and abdomen motion at selected locations and spirometry measurements. Methods: A Patient-specific 3D triangular surface mesh of the lung region at end-expiration (EE) phase was obtained by threshold-based segmentation method. For each patient, a spirometer recorded the flow volume changes of the lungs; and 192 selected points at a regular spacing of 2cm X 2cm matrix points over a total area of 34cm X 24cm on the surface of chest and abdomen was used to detect chest wall motions. Preprocessing techniques such as QR factorization with column pivoting (QRCP) were employed to remove redundant observations of the chest and abdominal area. To create a statistical model between the lung surface and the corresponding surrogate signals, we developed a predictive model based on canonical ridge regression (CRR). Two unique weighting vectors were selected for each vertex on the surface of the lung, and they were optimized during the training process using the all other phases of 4D-CT except the end-inspiration (EI) phase. These parameters were employed to predict the vertices locations of a testing data set, which was the EI phase of 4D-CT. Results: For ten lung cancer patients, the deformation vector field of each vertex of lung surface mesh was estimated from the external motion at selected positions on the chest wall surface plus spirometry measurements. The average estimation of 98th percentile of error was less than 1 mm (AP= 0.85, RL= 0.61, and SI= 0.82). Conclusion: The developed predictive model provides a non-invasive approach to derive lung boundary condition. Together with personalized biomechanical respiration modelling, the proposed model can be used to derive the lung tumor motion during radiation therapy accurately from non-invasive measurements.

  9. TH-CD-207A-05: Lung Surface Deformation Vector Fields Prediction by Monitoring Respiratory Surrogate Signals

    Energy Technology Data Exchange (ETDEWEB)

    Nasehi Tehrani, J; Wang, J [UT Southwestern Medical Center, Dallas, TX (United States); McEwan, A [The University of Sydney, Sydney, New South Wales (Australia)

    2016-06-15

    Purpose: In this study, we developed and evaluated a method for predicting lung surface deformation vector fields (SDVFs) based on surrogate signals such as chest and abdomen motion at selected locations and spirometry measurements. Methods: A Patient-specific 3D triangular surface mesh of the lung region at end-expiration (EE) phase was obtained by threshold-based segmentation method. For each patient, a spirometer recorded the flow volume changes of the lungs; and 192 selected points at a regular spacing of 2cm X 2cm matrix points over a total area of 34cm X 24cm on the surface of chest and abdomen was used to detect chest wall motions. Preprocessing techniques such as QR factorization with column pivoting (QRCP) were employed to remove redundant observations of the chest and abdominal area. To create a statistical model between the lung surface and the corresponding surrogate signals, we developed a predictive model based on canonical ridge regression (CRR). Two unique weighting vectors were selected for each vertex on the surface of the lung, and they were optimized during the training process using the all other phases of 4D-CT except the end-inspiration (EI) phase. These parameters were employed to predict the vertices locations of a testing data set, which was the EI phase of 4D-CT. Results: For ten lung cancer patients, the deformation vector field of each vertex of lung surface mesh was estimated from the external motion at selected positions on the chest wall surface plus spirometry measurements. The average estimation of 98th percentile of error was less than 1 mm (AP= 0.85, RL= 0.61, and SI= 0.82). Conclusion: The developed predictive model provides a non-invasive approach to derive lung boundary condition. Together with personalized biomechanical respiration modelling, the proposed model can be used to derive the lung tumor motion during radiation therapy accurately from non-invasive measurements.

  10. Treatment of the X and γ rays lung monitoring spectra obtained by using HP-Ge detectors in case of exposures to uranium

    International Nuclear Information System (INIS)

    Berard, P.; Pourret, O.; Aussel, J.P.; Rongier, E.

    1996-01-01

    A lung monitoring counting spectrum can be described as a random phenomenon. Channel-by-channel Poisson-type modelling was verified for cases of pure background. When carrying out spectral analysis for qualitative research, one must work with the sum of the detectors. The quantification must be calculated detector by detector. Statistical tests make it possible to certify that one or several peaks are really present in the organism. The calculations are currently made with automatic spectral analysis, peak search, specific area, statistics and probability of the real presence of analytic photo peak taking into account the morphological parameters of the worker. The results are analysed detector by detector, with and without the background of the room. Detection limits obtained in Pierrelatte in monitoring measurement conditions were assessed for variable tissues covering the range of subjects to be examined. For each subject, the calculations are made taking into account the equivalent tissue thicknesses derived from individual morphological parameters. This method makes it possible to quantify lung activities with a detection limit of 3.9 Bq ( 235 U; thirty minutes counting time; reference man parameters) and to monitor exposure to the different compounds of uranium. (author)

  11. [Lung auscultation--an overview].

    Science.gov (United States)

    Bürgi, Urs; Huber, Lars Christian

    2015-07-01

    The auscultation of the lungs is - among anamnesis - the most important part in the assessment of patients presenting with pulmonary symptoms. The lung auscultation is reproducible, cost efficient and very helpful to distinguish between differential diagnoses, in particular in emergency situations. Detection and description of lung sounds requires experience and should be performed by strict adherence to the internationally accepted terminology. © Georg Thieme Verlag KG Stuttgart · New York.

  12. Sound knowledge

    DEFF Research Database (Denmark)

    Kauffmann, Lene Teglhus

    as knowledge based on reflexive practices. I chose ‘health promotion’ as the field for my research as it utilises knowledge produced in several research disciplines, among these both quantitative and qualitative. I mapped out the institutions, actors, events, and documents that constituted the field of health...... of the research is to investigate what is considered to ‘work as evidence’ in health promotion and how the ‘evidence discourse’ influences social practices in policymaking and in research. From investigating knowledge practices in the field of health promotion, I develop the concept of sound knowledge...... result of a rigorous and standardized research method. However, this anthropological analysis shows that evidence and evidence-based is a hegemonic ‘way of knowing’ that sometimes transposes everyday reasoning into an epistemological form. However, the empirical material shows a variety of understandings...

  13. WODA Technical Guidance on Underwater Sound from Dredging.

    Science.gov (United States)

    Thomsen, Frank; Borsani, Fabrizio; Clarke, Douglas; de Jong, Christ; de Wit, Pim; Goethals, Fredrik; Holtkamp, Martine; Martin, Elena San; Spadaro, Philip; van Raalte, Gerard; Victor, George Yesu Vedha; Jensen, Anders

    2016-01-01

    The World Organization of Dredging Associations (WODA) has identified underwater sound as an environmental issue that needs further consideration. A WODA Expert Group on Underwater Sound (WEGUS) prepared a guidance paper in 2013 on dredging sound, including a summary of potential impacts on aquatic biota and advice on underwater sound monitoring procedures. The paper follows a risk-based approach and provides guidance for standardization of acoustic terminology and methods for data collection and analysis. Furthermore, the literature on dredging-related sounds and the effects of dredging sounds on marine life is surveyed and guidance on the management of dredging-related sound risks is provided.

  14. Sound Search Engine Concept

    DEFF Research Database (Denmark)

    2006-01-01

    Sound search is provided by the major search engines, however, indexing is text based, not sound based. We will establish a dedicated sound search services with based on sound feature indexing. The current demo shows the concept of the sound search engine. The first engine will be realased June...

  15. Noninvasive monitoring of gas in the lungs and intestines of newborn infants using diode lasers: feasibility study.

    Science.gov (United States)

    Lundin, Patrik; Svanberg, Emilie Krite; Cocola, Lorenzo; Lewander Xu, Märta; Somesfalean, Gabriel; Andersson-Engels, Stefan; Jahr, John; Fellman, Vineta; Svanberg, Katarina; Svanberg, Sune

    2013-12-01

    Preterm newborn infants have a high morbidity rate. The most frequently affected organs where free gas is involved are the lungs and intestines. In respiratory distress syndrome, both hyperexpanded and atelectatic (collapsed) areas occur, and in necrotizing enterocolitis, intramural gas may appear in the intestine. Today, these conditions are diagnosed with x-ray radiography. A bed-side, rapid, nonintrusive, and gas-specific technique for in vivo gas sensing would improve diagnosis. We report the use of noninvasive laser spectroscopy, for the first time, to assess gas content in the lungs and intestines of three full-term infants. Water vapor and oxygen were studied with two low-power diode lasers, illuminating the skin and detecting light a few centimeters away. Water vapor was easily detected in the intestines and was also observed in the lungs. The relatively thick chest walls of the infants prevented detection of the weaker oxygen signal in this study. However, results from a previous phantom study, together with scaling of the results presented here to the typical chest-wall thickness of preterm infants, suggest that oxygen also should be detectable in their lungs.

  16. Rearranged EML4-ALK fusion transcripts sequester in circulating blood platelets and enable blood-based crizotinib response monitoring in non-small-cell lung cancer

    Science.gov (United States)

    Nilsson, R. Jonas A.; Karachaliou, Niki; Berenguer, Jordi; Gimenez-Capitan, Ana; Schellen, Pepijn; Teixido, Cristina; Tannous, Jihane; Kuiper, Justine L.; Drees, Esther; Grabowska, Magda; van Keulen, Marte; Heideman, Danielle A.M.; Thunnissen, Erik; Dingemans, Anne-Marie C.; Viteri, Santiago; Tannous, Bakhos A.; Drozdowskyj, Ana; Rosell, Rafael; Smit, Egbert F.; Wurdinger, Thomas

    2016-01-01

    Purpose: Non-small-cell lung cancers harboring EML4-ALK rearrangements are sensitive to crizotinib. However, despite initial response, most patients will eventually relapse, and monitoring EML4-ALK rearrangements over the course of treatment may help identify these patients. However, challenges associated with serial tumor biopsies have highlighted the need for blood-based assays for the monitoring of biomarkers. Platelets can sequester RNA released by tumor cells and are thus an attractive source for the non-invasive assessment of biomarkers. Methods: EML4-ALK rearrangements were analyzed by RT-PCR in platelets and plasma isolated from blood obtained from 77 patients with non-small-cell lung cancer, 38 of whom had EML4-ALK-rearranged tumors. In a subset of 29 patients with EML4-ALK-rearranged tumors who were treated with crizotinib, EML4-ALK rearrangements in platelets were correlated with progression-free and overall survival. Results: RT-PCR demonstrated 65% sensitivity and 100% specificity for the detection of EML4-ALK rearrangements in platelets. In the subset of 29 patients treated with crizotinib, progression-free survival was 3.7 months for patients with EML4-ALK+ platelets and 16 months for those with EML4-ALK− platelets (hazard ratio, 3.5; P = 0.02). Monitoring of EML4-ALK rearrangements in the platelets of one patient over a period of 30 months revealed crizotinib resistance two months prior to radiographic disease progression. Conclusions: Platelets are a valuable source for the non-invasive detection of EML4-ALK rearrangements and may prove useful for predicting and monitoring outcome to crizotinib, thereby improving clinical decisions based on radiographic imaging alone. PMID:26544515

  17. Patterns and correlates of adherence to self-monitoring in lung transplant recipients during the first 12 months after discharge from transplant.

    Science.gov (United States)

    Hu, Lu; DeVito Dabbs, Annette; Dew, Mary Amanda; Sereika, Susan M; Lingler, Jennifer H

    2017-08-01

    Self-monitoring of lung function, vital signs, and symptoms is crucial for lung transplant recipients (LTRs) to ensure early detection of complications and prompt intervention. This study sought to identify patterns and correlates of adherence to self-monitoring among LTRs over the first 12 months post-discharge from transplant. This study analyzed existing data from the usual care arm participants of a randomized clinical trial who tracked self-monitoring activities using paper-and-pencil logs. Adherence was calculated as the percent of days LTRs recorded any self-monitoring data per interval: hospital discharge-2 months, 3-6 months, and 7-12 months. The sample (N=91) was mostly white (87.9%), male (61.5%), with a mean age of 57.2±13.8 years. Group-based trajectory analyses revealed two groups: (i) moderately adherent with slow decline (n=29, 31.9%) and (ii) persistently nonadherent (n=62, 68.1%). Multivariate binary logistic regression revealed the following baseline factors increased the risk in the persistently nonadherent group: female (P=.035), higher anxiety (P=.008), and weaker sense of personal control over health (P=.005). Poorer physical health over 12 months were associated with increased risk in the persistently nonadherent group (P=.004). This study highlighted several modifiable factors for future interventions to target, including reducing post-transplant anxiety, and strengthening sense of personal control over health in LTRs. © 2017 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

  18. NASA Space Sounds API

    Data.gov (United States)

    National Aeronautics and Space Administration — NASA has released a series of space sounds via sound cloud. We have abstracted away some of the hassle in accessing these sounds, so that developers can play with...

  19. The Sound of Science

    Science.gov (United States)

    Merwade, Venkatesh; Eichinger, David; Harriger, Bradley; Doherty, Erin; Habben, Ryan

    2014-01-01

    While the science of sound can be taught by explaining the concept of sound waves and vibrations, the authors of this article focused their efforts on creating a more engaging way to teach the science of sound--through engineering design. In this article they share the experience of teaching sound to third graders through an engineering challenge…

  20. Sounds Exaggerate Visual Shape

    Science.gov (United States)

    Sweeny, Timothy D.; Guzman-Martinez, Emmanuel; Ortega, Laura; Grabowecky, Marcia; Suzuki, Satoru

    2012-01-01

    While perceiving speech, people see mouth shapes that are systematically associated with sounds. In particular, a vertically stretched mouth produces a /woo/ sound, whereas a horizontally stretched mouth produces a /wee/ sound. We demonstrate that hearing these speech sounds alters how we see aspect ratio, a basic visual feature that contributes…

  1. Making Sound Connections

    Science.gov (United States)

    Deal, Walter F., III

    2007-01-01

    Sound provides and offers amazing insights into the world. Sound waves may be defined as mechanical energy that moves through air or other medium as a longitudinal wave and consists of pressure fluctuations. Humans and animals alike use sound as a means of communication and a tool for survival. Mammals, such as bats, use ultrasonic sound waves to…

  2. Little Sounds

    Directory of Open Access Journals (Sweden)

    Baker M. Bani-Khair

    2017-10-01

    Full Text Available The Spider and the Fly   You little spider, To death you aspire... Or seeking a web wider, To death all walking, No escape you all fighters… Weak and fragile in shape and might, Whatever you see in the horizon, That is destiny whatever sight. And tomorrow the spring comes, And the flowers bloom, And the grasshopper leaps high, And the frogs happily cry, And the flies smile nearby, To that end, The spider has a plot, To catch the flies by his net, A mosquito has fallen down in his net, Begging him to set her free, Out of that prison, To her freedom she aspires, Begging...Imploring...crying,  That is all what she requires, But the spider vows never let her free, His power he admires, Turning blind to light, And with his teeth he shall bite, Leaving her in desperate might, Unable to move from site to site, Tied up with strings in white, Wrapped up like a dead man, Waiting for his grave at night,   The mosquito says, Oh little spider, A stronger you are than me in power, But listen to my words before death hour, Today is mine and tomorrow is yours, No escape from death... Whatever the color of your flower…     Little sounds The Ant The ant is a little creature with a ferocious soul, Looking and looking for more and more, You can simply crush it like dead mold, Or you can simply leave it alone, I wonder how strong and strong they are! Working day and night in a small hole, Their motto is work or whatever you call… A big boon they have and joy in fall, Because they found what they store, A lesson to learn and memorize all in all, Work is something that you should not ignore!   The butterfly: I’m the butterfly Beautiful like a blue clear sky, Or sometimes look like snow, Different in colors, shapes and might, But something to know that we always die, So fragile, weak and thin, Lighter than a glimpse and delicate as light, Something to know for sure… Whatever you have in life and all these fields, You are not happier than a butterfly

  3. A pilot study to monitor changes in spirometry and lung volume, following an exacerbation of Chronic Obstructive Pulmonary Disease (COPD), as part of a supported discharge program.

    Science.gov (United States)

    Cushen, Breda; McCormack, Niamh; Hennigan, Kerrie; Sulaiman, Imran; Costello, Richard W; Deering, Brenda

    2016-10-01

    One-third of patients with an exacerbation of Chronic Obstructive Pulmonary Disease(COPD) are re-hospitalised at 90 days. Exacerbation recovery is associated with reductions in lung hyperinflation and improvements in symptoms and physical activity. We assessed the feasibility of monitoring these clinical parameters in the home. We hypothesised that the degree of change in spirometry and lung volumes differs between those who had an uneventful recovery and those who experienced a further exacerbation. Hospitalised patients with an acute exacerbation of COPD referred for a supported discharge program participated in the study. Spirometry and Inspiratory Vital Capacity(IVC) were measured in the home at Days 1, 14 and 42 post-discharge. Patients also completed Medical Research Council(MRC), Borg and COPD Assessment Test(CAT) scores and were provided with a tri-axial accelerometer. Any new exacerbation events were recorded. Sixty-five patients with 72 exacerbation episodes were recruited. Fifty percent experienced a second exacerbation. Adequate IVC measurements were achieved by 90%, while only 70% completed spirometry. Uneventful recovery was accompanied by significant improvements in physiological measurements at day14, improved symptom scores and step count, p volumes, symptoms and step count following a COPD exacerbation may help to identify patients at risk of re-exacerbation. It is feasible to carry out these assessments in the home as part of a supported discharge programme. Copyright © 2016 Elsevier Ltd. All rights reserved.

  4. Lung cancer

    International Nuclear Information System (INIS)

    Aisner, J.

    1985-01-01

    This book contains 13 chapters. Some of the chapter titles are: The Pathology of Lung Cancer; Radiotherapy for Non-Small-Cell Cancer of the Lung; Chemotherapy for Non-Small-Cell Lung Cancer; Immunotherapy in the Management of Lung Cancer; Preoperative Staging and Surgery for Non-Small-Cell Lung Cancer; and Prognostic Factors in Lung Cancer

  5. Risk-adjusted econometric model to estimate postoperative costs: an additional instrument for monitoring performance after major lung resection.

    Science.gov (United States)

    Brunelli, Alessandro; Salati, Michele; Refai, Majed; Xiumé, Francesco; Rocco, Gaetano; Sabbatini, Armando

    2007-09-01

    The objectives of this study were to develop a risk-adjusted model to estimate individual postoperative costs after major lung resection and to use it for internal economic audit. Variable and fixed hospital costs were collected for 679 consecutive patients who underwent major lung resection from January 2000 through October 2006 at our unit. Several preoperative variables were used to develop a risk-adjusted econometric model from all patients operated on during the period 2000 through 2003 by a stepwise multiple regression analysis (validated by bootstrap). The model was then used to estimate the postoperative costs in the patients operated on during the 3 subsequent periods (years 2004, 2005, and 2006). Observed and predicted costs were then compared within each period by the Wilcoxon signed rank test. Multiple regression and bootstrap analysis yielded the following model predicting postoperative cost: 11,078 + 1340.3X (age > 70 years) + 1927.8X cardiac comorbidity - 95X ppoFEV1%. No differences between predicted and observed costs were noted in the first 2 periods analyzed (year 2004, $6188.40 vs $6241.40, P = .3; year 2005, $6308.60 vs $6483.60, P = .4), whereas in the most recent period (2006) observed costs were significantly lower than the predicted ones ($3457.30 vs $6162.70, P model may be used as a methodologic template for economic audit in our specialty and complement more traditional outcome measures in the assessment of performance.

  6. Estimation of patient-specific imaging dose for real-time tumour monitoring in lung patients during respiratory-gated radiotherapy

    Science.gov (United States)

    Shiinoki, Takehiro; Onizuka, Ryota; Kawahara, Daisuke; Suzuki, Tatsuhiko; Yuasa, Yuki; Fujimoto, Koya; Uehara, Takuya; Hanazawa, Hideki; Shibuya, Keiko

    2018-03-01

    Purpose: To quantify the patient-specific imaging dose for real-time tumour monitoring in the lung during respiratory-gated stereotactic body radiotherapy (SBRT) in clinical cases using SyncTraX. Methods and Materials: Ten patients who underwent respiratory-gated SBRT with SyncTraX were enrolled in this study. The imaging procedure for real-time tumour monitoring using SyncTraX was simulated using Monte Carlo. We evaluated the dosimetric effect of a real-time tumour monitoring in a critical organ at risk (OAR) and the planning target volume (PTV) over the course of treatment. The relationship between skin dose and gating efficiency was also investigated. Results: For all patients, the mean D50 to the PTV, ipsilateral lung, liver, heart, spinal cord and skin was 118.3 (21.5–175.9), 31.9 (9.5–75.4), 15.4 (1.1–31.6), 10.1 (1.3–18.1), 25.0 (1.6–101.8), and 3.6 (0.9–7.1) mGy, respectively. The mean D2 was 352.0 (26.5–935.8), 146.4 (27.3–226.7), 90.7 (3.6–255.0), 42.2 (4.8–82.7), 88.0 (15.4–248.5), and 273.5 (98.3–611.6) mGy, respectively. The D2 of the skin dose was found to increase as the gating efficiency decreased. Conclusions: The additional dose to the PTV was at most 1.9% of the prescribed dose over the course of treatment for real-time tumour monitoring. For OARs, we could confirm the high dose region, which may not be susceptible to radiation toxicity. However, to reduce the skin dose from SyncTraX, it is necessary to increase the gating efficiency.

  7. Auscultation of the lung: past lessons, future possibilities.

    Science.gov (United States)

    Murphy, R L

    1981-01-01

    Review of the history of auscultation of the lung reveals few scientific investigations. The majority of these have led to inconclusive results. The mechanism of production of normal breath sounds remains uncertain. Hypotheses for the generation of adventitious sounds are unproven. Advances in instrumentation for lung sound recording and analysis have provided little of clinical value. There has been a recent resurgence of interest in lung sounds. Space-age technology has improved methodology for sonic analysis significantly. Lung sounds are complex signals that probably reflect regional lung pathophysiology. If they were understood more clearly important non-invasive diagnostic tools could be devised and the value of clinical auscultation could be improved. A multidisciplinary effort will be required to achieve this. PMID:7268687

  8. Enviromental contaminants in Puget Sound fish - Histological Preparation and Chemical Analyses of Puget Sound Fish

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — As part of a long-term contaminant-monitoring program of fish in Puget Sound and Georgia Basin, Washington Department of Fish and Wildlife (WDFW) and NWFSC have...

  9. Cystic Fibrosis: Are Volumetric Ultra-Low-Dose Expiratory CT Scans Sufficient for Monitoring Related Lung Disease?

    DEFF Research Database (Denmark)

    Loeve, Martine; Lequin, Maarten H; Bruijne, Marleen de

    2009-01-01

    Purpose: To assess whether chest computed tomography (CT) scores from ultra-low-dose end-expiratory scans alone could suffice for assessment of all cystic fibrosis (CF)-related structural lung abnormalities. Materials and Methods: In this institutional review board–approved study, 20 patients...... with CF aged 6–20 years (eight males, 12 females) underwent low-dose end-inspiratory CT and ultra-low-dose end-expiratory CT. Informed consent was obtained. Scans were randomized and scored by using the Brody-II CT scoring system to assess bronchiectasis, airway wall thickening, mucus plugging......-Altman plots. Results: Median age was 12.6 years (range, 6.3–20.3 years), median forced expiratory volume in 1 second was 100% (range, 46%–127%) of the predicted value, and median forced vital capacity was 99% (range, 61%–123%) of the predicted value. Very good agreement was observed between end...

  10. Technical Stability and Biological Variability in MicroRNAs from Dried Blood Spots: A Lung Cancer Therapy-Monitoring Showcase.

    Science.gov (United States)

    Kahraman, Mustafa; Laufer, Thomas; Backes, Christina; Schrörs, Hannah; Fehlmann, Tobias; Ludwig, Nicole; Kohlhaas, Jochen; Meese, Eckart; Wehler, Thomas; Bals, Robert; Keller, Andreas

    2017-09-01

    Different work flows have been proposed to use miRNAs as blood-borne biomarkers. In particular, the method used for collecting blood from patients can considerably influence the diagnostic results. We explored whether dried blood spots (DBSs) facilitate stable miRNA measurements and compared its technical stability with biological variability. First, we tested the stability of DBS samples by generating from 1 person 18 whole-genome-wide miRNA profiles of DBS samples that were exposed to different temperature and humidity conditions. Second, we investigated technical reproducibility by performing 7 replicates of DBS again from 1 person. Third, we investigated DBS samples from 53 patients with lung cancer undergoing different therapies. Across these 3 stages, 108 genome-wide miRNA profiles from DBS were generated and evaluated biostatistically. In the stability analysis, we observed that temperature and humidity had an overall limited influence on the miRNomes (average correlation between the different conditions of 0.993). Usage of a silica gel slightly diminished DBS' technical reproducibility. The 7 technical replicates had an average correlation of 0.996. The correlation with whole-blood PAXGene miRNomes of the same individual was remarkable (correlation of 0.88). Finally, evaluation of the samples from the 53 patients with lung cancer exposed to different therapies showed that the biological variations exceeded the technical variability significantly ( P work flow for profiling of whole miRNomes on the basis of samples collected from DBS. Biological variations exceeded technical variations significantly. DBS-based miRNA profiles will potentially further the translational character of miRNA biomarker studies. © 2017 American Association for Clinical Chemistry.

  11. Development and evaluation of a technique for in vivo monitoring of {sup 60}Co in the lungs

    Energy Technology Data Exchange (ETDEWEB)

    Mello, J.Q. de; Lucena, E.A.; Dantas, A.L.A.; Dantas, B.M., E-mail: bmdantas@ird.gov.br [Instituto de Radioprotecao e Dosimetria (IRD/CNEN-RJ), Rio de Janeiro, RJ (Brazil)

    2015-07-01

    {sup 60}Co is a fission product of {sup 235}U and represents a risk of internal exposure of workers in nuclear power plants, especially those involved in the maintenance of potentially contaminated parts and equipment. The control of {sup 60}Co intake by inhalation can be performed through in vivo monitoring. This work describes the evaluation of a technique through the minimum detectable activity and the corresponding minimum detectable effective doses, based on biokinetic and dosimetric models of {sup 60}Co in the human body. The results allow to state that the technique is suitable either for monitoring of occupational exposures or evaluation of accidental intakes. (author)

  12. A Wireless Electronic Esophageal Stethoscope for Continuous Monitoring of Cardiovascular and Respiratory Systems during Anaesthesia

    Directory of Open Access Journals (Sweden)

    Parsaei H.

    2017-03-01

    Full Text Available Background: The basic requirements for monitoring anesthetized patients during surgery are assessing cardiac and respiratory function. Esophageal stethoscopes have been developed for this purpose, but these devices may not provide clear heart and lung sound due to existence of various noises in operating rooms. In addition, the stethoscope is not applicable for continues monitoring, and it is unsuitable for observing inaccessible patients in some conditions such as during CT scan. Objective: A wireless electronic esophageal stethoscope is designed for continues auscultation of heart and lung sounds in anesthetized patients. The system consists of a transmitter and a receiver. The former acquires, amplifies and transmits the acquired sound signals to the latter via a frequency modulation transmitter. The receiver demodulates, amplifies, and delivers the received signal to a headphone to be heard by anesthesiologist. Results: The usability and effectiveness of the designed system was qualitatively evaluated by 5 anesthesiologists in Namazi Hospital and Shahid Chamran Hospital, Shiraz, Iran on 30 patients in several operating rooms in different conditions; e.g., when electro surgery instruments are working. Fortunately, the experts on average ranked good quality for the heard heart and lung sounds and very good on the user friendly being of the instrument. Conclusion: Evaluation results demonstrate that the developed system is capable of capturing and transmitting heart and lung sounds successfully. Therefore, it can be used to continuously monitor anesthetized patients’ cardiac and respiratory function. Since via the instrument wireless auscultation is possible, it could be suitable for observing inaccessible patients in several conditions such as during CT scan.

  13. A Wireless Electronic Esophageal Stethoscope for Continuous Monitoring of Cardiovascular and Respiratory Systems during Anaesthesia

    Science.gov (United States)

    Parsaei, H.; Vakily, A.; Shafiei, A.M.

    2017-01-01

    Background: The basic requirements for monitoring anesthetized patients during surgery are assessing cardiac and respiratory function. Esophageal stethoscopes have been developed for this purpose, but these devices may not provide clear heart and lung sound due to existence of various noises in operating rooms. In addition, the stethoscope is not applicable for continues monitoring, and it is unsuitable for observing inaccessible patients in some conditions such as during CT scan. Objective: A wireless electronic esophageal stethoscope is designed for continues auscultation of heart and lung sounds in anesthetized patients. The system consists of a transmitter and a receiver. The former acquires, amplifies and transmits the acquired sound signals to the latter via a frequency modulation transmitter. The receiver demodulates, amplifies, and delivers the received signal to a headphone to be heard by anesthesiologist. Results: The usability and effectiveness of the designed system was qualitatively evaluated by 5 anesthesiologists in Namazi Hospital and Shahid Chamran Hospital, Shiraz, Iran on 30 patients in several operating rooms in different conditions; e.g., when electro surgery instruments are working. Fortunately, the experts on average ranked good quality for the heard heart and lung sounds and very good on the user friendly being of the instrument. Conclusion: Evaluation results demonstrate that the developed system is capable of capturing and transmitting heart and lung sounds successfully. Therefore, it can be used to continuously monitor anesthetized patients’ cardiac and respiratory function. Since via the instrument wireless auscultation is possible, it could be suitable for observing inaccessible patients in several conditions such as during CT scan. PMID:28451580

  14. Annual Report: 2011-2012 Storm Season Sampling, Non-Dry Dock Stormwater Monitoring for Puget Sound Naval Shipyard, Bremerton, WA

    Energy Technology Data Exchange (ETDEWEB)

    Brandenberger, Jill M.; Metallo, David; Rupert, Brian; Johnston, Robert K.; Gebhart, Christine

    2013-07-03

    Annual PSNS non-dry dock storm water monitoring results for 2011-2012 storm season. Included are a brief description of the sampling procedures, storm event information, laboratory methods and data collection, a results and discussion section, and the conclusions and recommendations.

  15. Long-term monitoring program: Evaluating chronic exposure of harlequin ducks and sea otters to lingering Exxon Valdez Oil in Western Prince William Sound

    Science.gov (United States)

    Esler, Daniel N.; Bowen, Lizabeth; Miles, A. Keith; Ballachey, Brenda E.; Bodkin, James L.

    2015-01-01

    We found that average cytochrome P4501A induction (as measured by EROD activity) during March 2014 was not elevated in wintering harlequin ducks captured in areas of Prince William Sound oiled by the 1989 Exxon Valdez oil spill, relative to those captured in unoiled areas. This result is consistent with findings from March 2013. We interpret these findings to indicate that exposure of harlequin ducks to residual Exxon Valdez oil abated within 24 years after the original spill. Results from preceding sampling in 2011 indicated that EROD activity was elevated in harlequin ducks in oiled relative to unoiled areas, although the magnitude of elevation was lower than in previous years (1998-2009), suggesting that the rate or intensity of exposure was diminishing by 2011. The data presented in this report add to a growing body of literature indicating that persistence of oil in the environment, and exposure of wildlife to that oil, can occur over much longer time frames than previously assumed.

  16. Chaotic dynamics of respiratory sounds

    International Nuclear Information System (INIS)

    Ahlstrom, C.; Johansson, A.; Hult, P.; Ask, P.

    2006-01-01

    There is a growing interest in nonlinear analysis of respiratory sounds (RS), but little has been done to justify the use of nonlinear tools on such data. The aim of this paper is to investigate the stationarity, linearity and chaotic dynamics of recorded RS. Two independent data sets from 8 + 8 healthy subjects were recorded and investigated. The first set consisted of lung sounds (LS) recorded with an electronic stethoscope and the other of tracheal sounds (TS) recorded with a contact accelerometer. Recurrence plot analysis revealed that both LS and TS are quasistationary, with the parts corresponding to inspiratory and expiratory flow plateaus being stationary. Surrogate data tests could not provide statistically sufficient evidence regarding the nonlinearity of the data. The null hypothesis could not be rejected in 4 out of 32 LS cases and in 15 out of 32 TS cases. However, the Lyapunov spectra, the correlation dimension (D 2 ) and the Kaplan-Yorke dimension (D KY ) all indicate chaotic behavior. The Lyapunov analysis showed that the sum of the exponents was negative in all cases and that the largest exponent was found to be positive. The results are partly ambiguous, but provide some evidence of chaotic dynamics of RS, both concerning LS and TS. The results motivate continuous use of nonlinear tools for analysing RS data

  17. Chaotic dynamics of respiratory sounds

    Energy Technology Data Exchange (ETDEWEB)

    Ahlstrom, C. [Department of Biomedical Engineering, Linkoepings Universitet, IMT/LIU, Universitetssjukhuset, S-58185 Linkoeping (Sweden) and Biomedical Engineering, Orebro University Hospital, S-70185 Orebro (Sweden)]. E-mail: christer@imt.liu.se; Johansson, A. [Department of Biomedical Engineering, Linkoepings Universitet, IMT/LIU, Universitetssjukhuset, S-58185 Linkoeping (Sweden); Hult, P. [Department of Biomedical Engineering, Linkoepings Universitet, IMT/LIU, Universitetssjukhuset, S-58185 Linkoeping (Sweden); Biomedical Engineering, Orebro University Hospital, S-70185 Orebro (Sweden); Ask, P. [Department of Biomedical Engineering, Linkoepings Universitet, IMT/LIU, Universitetssjukhuset, S-58185 Linkoeping (Sweden); Biomedical Engineering, Orebro University Hospital, S-70185 Orebro (Sweden)

    2006-09-15

    There is a growing interest in nonlinear analysis of respiratory sounds (RS), but little has been done to justify the use of nonlinear tools on such data. The aim of this paper is to investigate the stationarity, linearity and chaotic dynamics of recorded RS. Two independent data sets from 8 + 8 healthy subjects were recorded and investigated. The first set consisted of lung sounds (LS) recorded with an electronic stethoscope and the other of tracheal sounds (TS) recorded with a contact accelerometer. Recurrence plot analysis revealed that both LS and TS are quasistationary, with the parts corresponding to inspiratory and expiratory flow plateaus being stationary. Surrogate data tests could not provide statistically sufficient evidence regarding the nonlinearity of the data. The null hypothesis could not be rejected in 4 out of 32 LS cases and in 15 out of 32 TS cases. However, the Lyapunov spectra, the correlation dimension (D {sub 2}) and the Kaplan-Yorke dimension (D {sub KY}) all indicate chaotic behavior. The Lyapunov analysis showed that the sum of the exponents was negative in all cases and that the largest exponent was found to be positive. The results are partly ambiguous, but provide some evidence of chaotic dynamics of RS, both concerning LS and TS. The results motivate continuous use of nonlinear tools for analysing RS data.

  18. Intracellular dynamics and fate of polystyrene nanoparticles in A549 Lung epithelial cells monitored by image (cross-) correlation spectroscopy and single particle tracking.

    Science.gov (United States)

    Deville, Sarah; Penjweini, Rozhin; Smisdom, Nick; Notelaers, Kristof; Nelissen, Inge; Hooyberghs, Jef; Ameloot, Marcel

    2015-10-01

    Novel insights in nanoparticle (NP) uptake routes of cells, their intracellular trafficking and subcellular targeting can be obtained through the investigation of their temporal and spatial behavior. In this work, we present the application of image (cross-) correlation spectroscopy (IC(C)S) and single particle tracking (SPT) to monitor the intracellular dynamics of polystyrene (PS) NPs in the human lung carcinoma A549 cell line. The ensemble kinetic behavior of NPs inside the cell was characterized by temporal and spatiotemporal image correlation spectroscopy (TICS and STICS). Moreover, a more direct interpretation of the diffusion and flow detected in the NP motion was obtained by SPT by monitoring individual NPs. Both techniques demonstrate that the PS NP transport in A549 cells is mainly dependent on microtubule-assisted transport. By applying spatiotemporal image cross-correlation spectroscopy (STICCS), the correlated motions of NPs with the early endosomes, late endosomes and lysosomes are identified. PS NPs were equally distributed among the endolysosomal compartment during the time interval of the experiments. The cotransport of the NPs with the lysosomes is significantly larger compared to the other cell organelles. In the present study we show that the complementarity of ICS-based techniques and SPT enables a consistent elaborate model of the complex behavior of NPs inside biological systems. Copyright © 2015 Elsevier B.V. All rights reserved.

  19. Cone-beam computed tomography for lung cancer - validation with CT and monitoring tumour response during chemo-radiation therapy.

    Science.gov (United States)

    Michienzi, Alissa; Kron, Tomas; Callahan, Jason; Plumridge, Nikki; Ball, David; Everitt, Sarah

    2017-04-01

    Cone-beam computed tomography (CBCT) is a valuable image-guidance tool in radiation therapy (RT). This study was initiated to assess the accuracy of CBCT for quantifying non-small cell lung cancer (NSCLC) tumour volumes compared to the anatomical 'gold standard', CT. Tumour regression or progression on CBCT was also analysed. Patients with Stage I-III NSCLC, prescribed 60 Gy in 30 fractions RT with concurrent platinum-based chemotherapy, routine CBCT and enrolled in a prospective study of serial PET/CT (baseline, weeks two and four) were eligible. Time-matched CBCT and CT gross tumour volumes (GTVs) were manually delineated by a single observer on MIM software, and were analysed descriptively and using Pearson's correlation coefficient (r) and linear regression (R 2 ). Of 94 CT/CBCT pairs, 30 patients were eligible for inclusion. The mean (± SD) CT GTV vs CBCT GTV on the four time-matched pairs were 95 (±182) vs 98.8 (±160.3), 73.6 (±132.4) vs 70.7 (±96.6), 54.7 (±92.9) vs 61.0 (±98.8) and 61.3 (±53.3) vs 62.1 (±47.9) respectively. Pearson's correlation coefficient (r) was 0.98 (95% CI 0.97-0.99, ρ < 0.001). The mean (±SD) CT/CBCT Dice's similarity coefficient was 0.66 (±0.16). Of 289 CBCT scans, tumours in 27 (90%) patients regressed by a mean (±SD) rate of 1.5% (±0.75) per fraction. The mean (±SD) GTV regression was 43.1% (±23.1) from the first to final CBCT. Primary lung tumour volumes observed on CBCT and time-matched CT are highly correlated (although not identical), thereby validating observations of GTV regression on CBCT in NSCLC. © 2016 The Royal Australian and New Zealand College of Radiologists.

  20. Sound wave transmission (image)

    Science.gov (United States)

    When sounds waves reach the ear, they are translated into nerve impulses. These impulses then travel to the brain where they are interpreted by the brain as sound. The hearing mechanisms within the inner ear, can ...

  1. Making fictions sound real

    DEFF Research Database (Denmark)

    Langkjær, Birger

    2010-01-01

    This article examines the role that sound plays in making fictions perceptually real to film audiences, whether these fictions are realist or non-realist in content and narrative form. I will argue that some aspects of film sound practices and the kind of experiences they trigger are related...... to basic rules of human perception, whereas others are more properly explained in relation to how aesthetic devices, including sound, are used to characterise the fiction and thereby make it perceptually real to its audience. Finally, I will argue that not all genres can be defined by a simple taxonomy...... of sounds. Apart from an account of the kinds of sounds that typically appear in a specific genre, a genre analysis of sound may also benefit from a functionalist approach that focuses on how sounds can make both realist and non-realist aspects of genres sound real to audiences....

  2. Principles of underwater sound

    National Research Council Canada - National Science Library

    Urick, Robert J

    1983-01-01

    ... the immediately useful help they need for sonar problem solving. Its coverage is broad-ranging from the basic concepts of sound in the sea to making performance predictions in such applications as depth sounding, fish finding, and submarine detection...

  3. An Antropologist of Sound

    DEFF Research Database (Denmark)

    Groth, Sanne Krogh

    2015-01-01

    PROFESSOR PORTRAIT: Sanne Krogh Groth met Holger Schulze, newly appointed professor in Musicology at the Department for Arts and Cultural Studies, University of Copenhagen, to a talk about anthropology of sound, sound studies, musical canons and ideology.......PROFESSOR PORTRAIT: Sanne Krogh Groth met Holger Schulze, newly appointed professor in Musicology at the Department for Arts and Cultural Studies, University of Copenhagen, to a talk about anthropology of sound, sound studies, musical canons and ideology....

  4. Propagation of sound

    DEFF Research Database (Denmark)

    Wahlberg, Magnus; Larsen, Ole Næsbye

    2017-01-01

    properties can be modified by sound absorption, refraction, and interference from multi paths caused by reflections.The path from the source to the receiver may be bent due to refraction. Besides geometrical attenuation, the ground effect and turbulence are the most important mechanisms to influence...... communication sounds for airborne acoustics and bottom and surface effects for underwater sounds. Refraction becomes very important close to shadow zones. For echolocation signals, geometric attenuation and sound absorption have the largest effects on the signals....

  5. Detectability of T1a lung cancer on digital chest radiographs: an observer-performance comparison among 2-megapixel general-purpose, 2-megapixel medical-purpose, and 3-megapixel medical-purpose liquid-crystal display (LCD) monitors.

    Science.gov (United States)

    Yabuuchi, Hidetake; Matsuo, Yoshio; Kamitani, Takeshi; Jinnnouchi, Mikako; Yonezawa, Masato; Yamasaki, Yuzo; Nagao, Michinobu; Kawanami, Satoshi; Okamoto, Tatsuro; Sasaki, Masayuki; Honda, Hiroshi

    2015-08-01

    There has been no comparison of detectability of small lung cancer between general and medical LCD monitors or no comparison of detectability of small lung cancer between solid and part-solid nodules. To compare the detectabilities of T1a lung cancer on chest radiographs on three LCD monitor types: 2-megapixel (MP) for general purpose (General), 2-MP for medical purpose (Medical), and 3-MP-Medical. Radiographs from forty patients with T1aN0M0 primary lung cancer (27 solid nodules, 13 part-solid nodules) and 60 patients with no abnormalities on both chest X-ray and computed tomography (CT) were consecutively collected. Five readers assessed 100 cases for each monitor. The observations were analyzed using receiver operating characteristic (ROC) analysis. A jackknife method was used for statistical analysis. A P value of General, 2-MP-Medical, and 3-MP-Medical LCD monitors were 0.86, 0.89, and 0.89, respectively; there were no significant differences among them. The average AUC for part-solid nodule detection using a 2-MP-General, 2-MP-Medical, and 3-MP-Medical LCD monitors were 0.77, 0.86, and 0.89, respectively. There were significant differences between the 2-MP-General and 2-MP-Medical LCD monitors (P = 0.043) and between the 2-MP-General and 3-MP-Medical LCD monitors (P = 0.027). There was no significant difference between the 2-MP-Medical and 3-MP-Medical LCD monitors. The average AUC for solid nodule detection using a 2-MP-General, 2-MP-Medical, and 3-MP-Medical LCD monitors were 0.90, 0.90, and 0.88, respectively; there were no significant differences among them. The mean AUC values for all and part-solid nodules of the low-experienced readers were significantly lower than those of the high-experienced readers with the 2 M-GP color LCD monitor (P general-purpose LCD monitor was significantly lower than those using medical-purpose LCD monitors. © The Foundation Acta Radiologica 2014.

  6. Abnormal sound detection device

    International Nuclear Information System (INIS)

    Yamada, Izumi; Matsui, Yuji.

    1995-01-01

    Only components synchronized with rotation of pumps are sampled from detected acoustic sounds, to judge the presence or absence of abnormality based on the magnitude of the synchronized components. A synchronized component sampling means can remove resonance sounds and other acoustic sounds generated at a synchronously with the rotation based on the knowledge that generated acoustic components in a normal state are a sort of resonance sounds and are not precisely synchronized with the number of rotation. On the other hand, abnormal sounds of a rotating body are often caused by compulsory force accompanying the rotation as a generation source, and the abnormal sounds can be detected by extracting only the rotation-synchronized components. Since components of normal acoustic sounds generated at present are discriminated from the detected sounds, reduction of the abnormal sounds due to a signal processing can be avoided and, as a result, abnormal sound detection sensitivity can be improved. Further, since it is adapted to discriminate the occurrence of the abnormal sound from the actually detected sounds, the other frequency components which are forecast but not generated actually are not removed, so that it is further effective for the improvement of detection sensitivity. (N.H.)

  7. Modelling Hyperboloid Sound Scattering

    DEFF Research Database (Denmark)

    Burry, Jane; Davis, Daniel; Peters, Brady

    2011-01-01

    The Responsive Acoustic Surfaces workshop project described here sought new understandings about the interaction between geometry and sound in the arena of sound scattering. This paper reports on the challenges associated with modelling, simulating, fabricating and measuring this phenomenon using...... both physical and digital models at three distinct scales. The results suggest hyperboloid geometry, while difficult to fabricate, facilitates sound scattering....

  8. Lung Emergencies

    Science.gov (United States)

    ... The Marfan Foundation Marfan & Related Disorders What is Marfan Syndrome? What are Related Disorders? What are the Signs? ... Emergencies Lung Emergencies Surgeries Lung Emergencies People with Marfan syndrome can be at increased risk of sudden lung ...

  9. Robust segmentation and retrieval of environmental sounds

    Science.gov (United States)

    Wichern, Gordon

    The proliferation of mobile computing has provided much of the world with the ability to record any sound of interest, or possibly every sound heard in a lifetime. The technology to continuously record the auditory world has applications in surveillance, biological monitoring of non-human animal sounds, and urban planning. Unfortunately, the ability to record anything has led to an audio data deluge, where there are more recordings than time to listen. Thus, access to these archives depends on efficient techniques for segmentation (determining where sound events begin and end), indexing (storing sufficient information with each event to distinguish it from other events), and retrieval (searching for and finding desired events). While many such techniques have been developed for speech and music sounds, the environmental and natural sounds that compose the majority of our aural world are often overlooked. The process of analyzing audio signals typically begins with the process of acoustic feature extraction where a frame of raw audio (e.g., 50 milliseconds) is converted into a feature vector summarizing the audio content. In this dissertation, a dynamic Bayesian network (DBN) is used to monitor changes in acoustic features in order to determine the segmentation of continuously recorded audio signals. Experiments demonstrate effective segmentation performance on test sets of environmental sounds recorded in both indoor and outdoor environments. Once segmented, every sound event is indexed with a probabilistic model, summarizing the evolution of acoustic features over the course of the event. Indexed sound events are then retrieved from the database using different query modalities. Two important query types are sound queries (query-by-example) and semantic queries (query-by-text). By treating each sound event and semantic concept in the database as a node in an undirected graph, a hybrid (content/semantic) network structure is developed. This hybrid network can

  10. Addressing glucose sensitivity measured by F-18 FDG PET in lung cancers for radiation treatment planning and monitoring

    International Nuclear Information System (INIS)

    Wong, Ching-yee Oliver; Thie, Joseph; Gaskill, Marianne; Kestin, Larry; Yan Di; Cheng, Vincent; Nagle, Conrad

    2006-01-01

    Purpose: To address glucose sensitivity in lung cancers before and after radiation treatment (Tx). Methods and Materials: Twelve patients were each studied with two pre-Tx positron emission tomography (PET) scans and 3 patients each with one post-Tx PET scan, with glucose concentration [Glc] and maximum standard uptake value (SUV) recorded. The pre-Tx glucose sensitivity, g from SUV 1 /SUV 2 = {[Glc] 1 /[Glc] 2 } g and Tx index, τ from SUV post-Tx /SUV pre-Tx = {[Glc] post-Tx /[Glc] pre-Tx } τ was calculated by linear regression. Pre-Tx SUVs were corrected to post-Tx Glc with g (SUV' pre-Tx ) for a pure Tx effect, R ln(SUV post-Tx /SUV' pre-Tx ). Results: There were no significant differences in SUV but [Glc] were different (96.4 ± 10.9 vs. 88.3 ± 10.5, p = 0.015) between two pre-Tx PET scans. Linear regression yielded g -0.79 and τ = -1.78 to -2.41 (p < 0.0005 in all). The %ΔSUV after Tx for 3 patients without vs. with g correction were different by -12%, 0%, and + 7%, suggesting varying effects from glucose. R values were also different and mean R (-0.81 ± 0.38) was significantly different from zero (p = 0.03), consistent with successful Tx as confirmed by clinico-radiologic follow-up. Conclusions: The extra dimension of glucose sensitivity, g besides SUV incorporated in the combined Tx-derived τ may be a useful global Tx evaluation index even with differing [Glc

  11. FDG PET in monitoring response to neoadjuvant chemoradiotherapy in patients with locally advanced non-small lung carcinoma

    International Nuclear Information System (INIS)

    Berlangieri, S. U.; Lee, S. T.; Chan, A. M.; Mitchell, P. L.; Knight, S. R.; Feigen, M. M.; Scott, A. M.

    2009-01-01

    Full text:Aim: The aim of our study was to correlate 18F-FDG PET response to neoadjuvant chemoradiotherapy with histopathology in patients with locally advanced non-small cell lung carcinoma. Methods: All patients with stage III NSCLC planned for surgery following induction chemotherpay and/or radiotherapy who underwent pre- and post-treatment FDG-PET between 2004 and 2007 were retrospectively reviewed. The PET scans were performed according to standard protocol. The clinical FDG-PET TNM stage was correlated with the histopathology of the surgical specimens. Results: There were 9 patients (6 M :3 F ), median age 59.7 years (range 49 to 73 years). Post-treatment FDG-PET correctly predicted mediastinal pathological N stage in 8/9 patients, with one patient having microsopic disease in two nodes. The post-treatment FDG-PET correctly predicted pathological T stage in 7/9 patients, with 2 patients having small volume T4 disease not detected by PET. Post-treatment FDG-PET correctly downstaged 4 patients. Of the 5 patients, incorrectly staged on the post-treatment FDG-PET, one patient had microscopic pN 2 disease, 2 had pN 1 disease, and 2 had pT 4 disease. Conclusion: Post-treatment FDG-PET is predictive of pathological nodal stage within the mediastinum in patients with locally advanced NSCLC treated with neoadjuvant chemoradiotherapy. FDG-PET does not detect microscopic or small volume disease, nor is it able to define the boundaries of mediastinal tissue invasion.

  12. Nutrition for Lung Cancer

    Science.gov (United States)

    ... Become An Advocate Volunteer Ways To Give Lung Cancer www.lung.org > Lung Health and Diseases > Lung Disease Lookup > ... Cancer Learn About Lung Cancer What Is Lung Cancer Lung Cancer Basics Causes & Risk Factors Lung Cancer Staging ...

  13. Acceptance and Use of Mobile Technology for Health Self-Monitoring in Lung Transplant Recipients during the First Year Post-Transplantation.

    Science.gov (United States)

    Jiang, Yun; Sereika, Susan M; Dabbs, Annette DeVito; Handler, Steven M; Schlenk, Elizabeth A

    2016-01-01

    To describe lung transplant recipients (LTRs') acceptance and use of mobile technology for health self-monitoring during the first year post-transplantation, and explore correlates of the use of technology in the 0 to 2, >2 to ≤6, >6 to ≤12, and 0 to 12 months. Secondary analysis of data from 96 LTR assigned to use Pocket PATH(®), a smartphone application, for daily health self-monitoring in a randomized controlled trial. Use of Pocket PATH was categorized as low, moderate, and high use. Proportional odds models for ordinal logistic regression were employed to explore correlates of use of technology. LTR reported high acceptance of Pocket PATH at baseline. However, acceptance was not associated with actual use over the 12 months (p=0.45~0.96). Actual use decreased across time intervals (ptechnology training (p=0.02) in the first 2 months. Higher use from >2 to ≤6 months was associated with greater satisfaction with technology training (OR=3.37, p=0.01) and shorter length of hospital stay (OR=0.98, p=0.02). Higher use from >6 to ≤12 months was associated with older age (OR=1.05, p=0.02), lower psychological distress (OR=0.43, p=0.02), and better physical functioning (OR=1.09, p=0.01). Higher use over 12 months was also associated with older age (OR=1.05, p=0.007), better physical functioning (OR=1.13, p=0.001), and greater satisfaction with technology training (OR=3.05, p=0.02). Correlates were different for short- and long-term use of mobile technology for health self-monitoring in the first year post-transplantation. It is important to follow up with LTR with longer hospital stay, poor physical functioning, and psychological distress, providing ongoing education to improve their long-term use of technology for health self-monitoring.

  14. 78 FR 13869 - Puget Sound Energy, Inc.; Puget Sound Energy, Inc.; Puget Sound Energy, Inc.; Puget Sound Energy...

    Science.gov (United States)

    2013-03-01

    ...-123-LNG; 12-128-NG; 12-148-NG; 12- 158-NG] Puget Sound Energy, Inc.; Puget Sound Energy, Inc.; Puget Sound Energy, Inc.; Puget Sound Energy, Inc.; Puget Sound Energy, Inc.; CE FLNG, LLC; Consolidated...-NG Puget Sound Energy, Inc Order granting long- term authority to import/export natural gas from/to...

  15. Identification of Circulating Long Noncoding RNA Linc00152 as a Novel Biomarker for Diagnosis and Monitoring of Non-Small-Cell Lung Cancer

    Directory of Open Access Journals (Sweden)

    Nandi Li

    2017-01-01

    Full Text Available Objective. Long noncoding RNAs (lncRNAs have been reported to play vital roles in non-small-cell lung cancer (NSCLC. Recently, long noncoding RNA Linc00152 has been reported to play important roles in various cancers. In this study, our aim was to investigate its expression pattern and clinical significance and further evaluate its diagnostic value for NSCLC. Methods. The levels of Linc00152 were detected in NSCLC tissues and plasma samples by quantitative real-time PCR (qRT-PCR. Receiver operating characteristic (ROC curves were depicted to evaluate the diagnostic value. Results. We found that Linc00152 levels were upregulated in both NSCLC tissues and plasma samples. Plasma Linc00152 levels were significantly lower in postoperative samples than in preoperative samples. Besides, high Linc00152 expression was significantly correlated with tumor size (r=0.293, P=0.005 and tumor stage (r=0.324, P=0.011. The ROC curves indicated that plasma Linc00152 has high diagnostic accuracy for NSCLC, and the area under curve (AUC for NSCLC versus healthy was 0.816 (95% CI: 0.757–0.875. Moreover, we found that the combination of Linc00152 and CEA could provide a more powerful diagnosis efficiency than Linc00152 or CEA alone (AUC = 0.881, 95% CI: 0.836–0.926. Conclusions. Plasma Linc00152 could serve as a promising biomarker for diagnosing and monitoring NSCLC.

  16. MRI of the lung

    Energy Technology Data Exchange (ETDEWEB)

    Kauczor, Hans-Ulrich (ed.) [University Clinic Heidelberg (Germany). Diagnostic and Interventional Radiology

    2009-07-01

    For a long time, only chest X-ray and CT were used to image lung structure, while nuclear medicine was employed to assess lung function. During the past decade significant developments have been achieved in the field of magnetic resonance imaging (MRI), enabling MRI to enter the clinical arena of chest imaging. Standard protocols can now be implemented on up-to-date scanners, allowing MRI to be used as a first-line imaging modality for various lung diseases, including cystic fibrosis, pulmonary hypertension and even lung cancer. The diagnostic benefits stem from the ability of MRI to visualize changes in lung structure while simultaneously imaging different aspects of lung function, such as perfusion, respiratory motion, ventilation and gas exchange. On this basis, novel quantitative surrogates for lung function can be obtained. This book provides a comprehensive overview of how to use MRI for imaging of lung disease. Special emphasis is placed on benign diseases requiring regular monitoring, given that it is patients with these diseases who derive the greatest benefit from the avoidance of ionizing radiation. (orig.)

  17. Sound a very short introduction

    CERN Document Server

    Goldsmith, Mike

    2015-01-01

    Sound is integral to how we experience the world, in the form of noise as well as music. But what is sound? What is the physical basis of pitch and harmony? And how are sound waves exploited in musical instruments? Sound: A Very Short Introduction looks at the science of sound and the behaviour of sound waves with their different frequencies. It also explores sound in different contexts, covering the audible and inaudible, sound underground and underwater, acoustic and electronic sound, and hearing in humans and animals. It concludes with the problem of sound out of place—noise and its reduction.

  18. Sound Insulation between Dwellings

    DEFF Research Database (Denmark)

    Rasmussen, Birgit

    2011-01-01

    Regulatory sound insulation requirements for dwellings exist in more than 30 countries in Europe. In some countries, requirements have existed since the 1950s. Findings from comparative studies show that sound insulation descriptors and requirements represent a high degree of diversity...... and initiate – where needed – improvement of sound insulation of new and existing dwellings in Europe to the benefit of the inhabitants and the society. A European COST Action TU0901 "Integrating and Harmonizing Sound Insulation Aspects in Sustainable Urban Housing Constructions", has been established and runs...... 2009-2013. The main objectives of TU0901 are to prepare proposals for harmonized sound insulation descriptors and for a European sound classification scheme with a number of quality classes for dwellings. Findings from the studies provide input for the discussions in COST TU0901. Data collected from 24...

  19. A efetividade dos testes complementares no acompanhamento da intervenção terapêutica no transtorno fonológico Effectiveness of complementary tests in monitoring therapeutic intervention in speech sound disorders

    Directory of Open Access Journals (Sweden)

    Haydée Fiszbein Wertzner

    2012-12-01

    Full Text Available O planejamento e a evolução terapêutica de crianças com transtorno fonológico estão diretamente relacionados à avaliação inicial e aos testes complementares aplicados. Acompanhar a evolução do caso por meio de verificações regulares acrescenta informações importantes à avaliação diagnóstica, o que permite fortalecer achados iniciais a respeito da dificuldade subjacente identificada na avaliação inicial. Assim, no presente estudo de caso verificou-se a efetividade e a eficiência da aplicação do índice de porcentagem de consoantes corretas revisado (PCC-R bem como dos testes complementares de inconsistência de fala, de estimulabilidade e de habilidades metafonológicas no acompanhamento da intervenção terapêutica em crianças com transtorno fonológico. Participaram deste estudo três crianças do gênero masculino. Na data da avaliação inicial o Caso 1 tinha 6 anos e 9 meses de idade, o Caso 2, 8 anos e 10 meses, e o Caso 3, 9 anos e 7 meses. Além da avaliação específica da fonologia, foram aplicados testes complementares que auxiliaram na verificação da dificuldade subjacente específica em cada um dos casos. Desta forma, os sujeitos foram submetidos à avaliação de habilidades metafonológicas, à prova de inconsistência de fala e de estimulabilidade. A análise conjunta dos dados permitiu constatar que os testes selecionados foram efetivos e eficientes tanto para complementar o diagnóstico como para indicar mudanças nos três casos de crianças com transtorno fonológico.Therapeutic planning and evolution of children with speech sound disorders are related to both the initial assessment and to the complementary tests selected to be applied. Monitoring the case by regular evaluations adds important information to the diagnosis, which allows strengthening the initial findings with regards to the underlying deficits identified in the initial evaluation. The aim of this case report was to verify the

  20. The velocity of sound

    International Nuclear Information System (INIS)

    Beyer, R.T.

    1985-01-01

    The paper reviews the work carried out on the velocity of sound in liquid alkali metals. The experimental methods to determine the velocity measurements are described. Tables are presented of reported data on the velocity of sound in lithium, sodium, potassium, rubidium and caesium. A formula is given for alkali metals, in which the sound velocity is a function of shear viscosity, atomic mass and atomic volume. (U.K.)

  1. Michael Jackson's Sound Stages

    OpenAIRE

    Morten Michelsen

    2012-01-01

    In order to discuss analytically spatial aspects of recorded sound William Moylan’s concept of ‘sound stage’ is developed within a musicological framework as part of a sound paradigm which includes timbre, texture and sound stage. Two Michael Jackson songs (‘The Lady in My Life’ from 1982 and ‘Scream’ from 1995) are used to: a) demonstrate the value of such a conceptualisation, and b) demonstrate that the model has its limits, as record producers in the 1990s began ignoring the conventions of...

  2. What is Sound?

    OpenAIRE

    Nelson, Peter

    2014-01-01

    What is sound? This question is posed in contradiction to the every-day understanding that sound is a phenomenon apart from us, to be heard, made, shaped and organised. Thinking through the history of computer music, and considering the current configuration of digital communi-cations, sound is reconfigured as a type of network. This network is envisaged as non-hierarchical, in keeping with currents of thought that refuse to prioritise the human in the world. The relationship of sound to musi...

  3. Light and Sound

    CERN Document Server

    Karam, P Andrew

    2010-01-01

    Our world is largely defined by what we see and hear-but our uses for light and sound go far beyond simply seeing a photo or hearing a song. A concentrated beam of light, lasers are powerful tools used in industry, research, and medicine, as well as in everyday electronics like DVD and CD players. Ultrasound, sound emitted at a high frequency, helps create images of a developing baby, cleans teeth, and much more. Light and Sound teaches how light and sound work, how they are used in our day-to-day lives, and how they can be used to learn about the universe at large.

  4. Early Sound Symbolism for Vowel Sounds

    Directory of Open Access Journals (Sweden)

    Ferrinne Spector

    2013-06-01

    Full Text Available Children and adults consistently match some words (e.g., kiki to jagged shapes and other words (e.g., bouba to rounded shapes, providing evidence for non-arbitrary sound–shape mapping. In this study, we investigated the influence of vowels on sound–shape matching in toddlers, using four contrasting pairs of nonsense words differing in vowel sound (/i/ as in feet vs. /o/ as in boat and four rounded–jagged shape pairs. Crucially, we used reduplicated syllables (e.g., kiki vs. koko rather than confounding vowel sound with consonant context and syllable variability (e.g., kiki vs. bouba. Toddlers consistently matched words with /o/ to rounded shapes and words with /i/ to jagged shapes (p < 0.01. The results suggest that there may be naturally biased correspondences between vowel sound and shape.

  5. Original monitoring of desert dust in African air masses transported over the Mediterranean Sea by quasi-Lagrangian drifting balloons and sounding balloons during the summer 2013 ChArMEx field campaign

    Science.gov (United States)

    Dulac, F.; Renard, J. B.; Durand, P.; Denjean, C.; Bourgeois, Q.; Vignelles, D.; Jeannot, M.; Mallet, M.; Verdier, N.

    2017-12-01

    This study focuses on in situ balloon-borne measurements of mineral dust from summer regional field campaigns in the western Mediterranean basin performed in the framework of ChArMEx (the Chemistry and Aerosol Mediterranean Experiment; see special issue https://www.atmos-chem-phys.net/special_issue334.html). Due to long-range transport from Africa, the lower troposphere over this regional sea is subject to high levels of desert dust with a maximum during the long dry and sunny Mediterranean summer season. Based on developments of boundary-layer pressurized balloons (BLPBs) and of a dedicated optical particle counter named LOAC (Light Optical Aerosol Counter/sizer), we were able to perform original quasi-Lagrangian monitoring of desert dust aerosols over the sea. The strategy combined classical sounding balloons and drifting BLPBs to document both the vertical distribution and long-range transport. A total of 27 LOAC flights were successfully conducted from Minorca Isl. (Spain) or Levant Isl. (France), during 4 Saharan dust transport events, including 10 flights with BLPBs at drifting altitudes between 2.0 and 3.3 km above sea level. The longest flight exceeded 700 km and lasted more than 25 h. Numerous tests and validations of LOAC measurements were performed to qualify the instrument, including comparisons with concurrent airborne measurements, sounding balloons, and remote sensing measurements with an AERONET sun-photometer, and a ground-based and the CALIOP lidar systems. Aerosol optical depths in the balloon vicinity did not exceed about 0.4 but the presence of turbid dust layers was confirmed thanks to dual scattering angle measurements by LOAC allowing the identification of dust particles. LOAC data could generally be fitted by a 3-mode lognormal distribution at roughly 0.2, 4 and 30 µm in modal diameter. Up to about 10-4 dust particles larger than 40 µm per cm3 are reported and no significant evolution of the size distribution was observed during the

  6. Motion monitoring during a course of lung radiotherapy with anchored electromagnetic transponders. Quantification of inter- and intrafraction motion and variability of relative transponder positions

    Energy Technology Data Exchange (ETDEWEB)

    Schmitt, Daniela [German Cancer Research Center (DKFZ), Division of Medical Physics in Radiation Oncology, Heidelberg (Germany); National Center for Radiation Research in Oncology (NCRO), Heidelberg Institute for Radiation Oncology (HIRO), Heidelberg (Germany); Heidelberg University Hospital, Department of Radiation Oncology, Heidelberg (Germany); Nill, Simeon; Oelfke, Uwe [German Cancer Research Center (DKFZ), Division of Medical Physics in Radiation Oncology, Heidelberg (Germany); National Center for Radiation Research in Oncology (NCRO), Heidelberg Institute for Radiation Oncology (HIRO), Heidelberg (Germany); The Institute of Cancer Research and The Royal Marsden NHS Foundation Trust, Joint Department of Physics, London (United Kingdom); Roeder, Falk [German Cancer Research Center (DKFZ), Clinical Cooperation Unit Molecular Radiooncology, Heidelberg (Germany); University of Munich (LMU), Department of Radiation Oncology, Munich (Germany); Gompelmann, Daniela; Herth, Felix [University of Heidelberg, Pneumology and Critical Care Medicine, Thoraxklinik, Heidelberg (Germany); German Center for Lung Research, Translational Lung Research Center Heidelberg (TLRC), Heidelberg (Germany)

    2017-10-15

    Anchored electromagnetic transponders for tumor motion monitoring during lung radiotherapy were clinically evaluated. First, intrafractional motion patterns were analyzed as well as their interfractional variations. Second, intra- and interfractional changes of the geometric transponder positions were investigated. Intrafractional motion data from 7 patients with an upper or middle lobe tumor and three implanted transponders each was used to calculate breathing amplitudes, overall motion amount and motion midlines in three mutual perpendicular directions and three-dimensionally (3D) for 162 fractions. For 6 patients intra- and interfractional variations in transponder distances and in the size of the triangle defined by the transponder locations over the treatment course were determined. Mean 3D values of all fractions were up to 4.0, 4.6 and 3.4 mm per patient for amplitude, overall motion amount and midline deviation, respectively. Intrafractional transponder distances varied with standard deviations up to 3.2 mm, while a maximal triangle shrinkage of 36.5% over 39 days was observed. Electromagnetic real-time motion monitoring was feasible for all patients. Detected respiratory motion was on average modest in this small cohort without lower lobe tumors, but changes in motion midline were of the same size as the amplitudes and greater midline motion can be observed in some fractions. Intra- and interfractional variations of the geometric transponder positions can be large, so for reliable motion management correlation between transponder and tumor motion needs to be evaluated per patient. (orig.) [German] Verankerte, elektromagnetische Transponder fuer die Bewegungserkennung des Tumors waehrend der Strahlentherapie der Lunge wurden klinisch evaluiert. Dafuer wurden intrafraktionelle Bewegungsmuster und ihre interfraktionellen Variationen analysiert und intra- und interfraktionelle Veraenderungen der geometrischen Transponderpositionen untersucht. Intrafraktionelle

  7. InfoSound

    DEFF Research Database (Denmark)

    Sonnenwald, Diane H.; Gopinath, B.; Haberman, Gary O.

    1990-01-01

    The authors explore ways to enhance users' comprehension of complex applications using music and sound effects to present application-program events that are difficult to detect visually. A prototype system, Infosound, allows developers to create and store musical sequences and sound effects with...

  8. Breaking the Sound Barrier

    Science.gov (United States)

    Brown, Tom; Boehringer, Kim

    2007-01-01

    Students in a fourth-grade class participated in a series of dynamic sound learning centers followed by a dramatic capstone event--an exploration of the amazing Trashcan Whoosh Waves. It's a notoriously difficult subject to teach, but this hands-on, exploratory approach ignited student interest in sound, promoted language acquisition, and built…

  9. Sound propagation in cities

    NARCIS (Netherlands)

    Salomons, E.; Polinder, H.; Lohman, W.; Zhou, H.; Borst, H.

    2009-01-01

    A new engineering model for sound propagation in cities is presented. The model is based on numerical and experimental studies of sound propagation between street canyons. Multiple reflections in the source canyon and the receiver canyon are taken into account in an efficient way, while weak

  10. OMNIDIRECTIONAL SOUND SOURCE

    DEFF Research Database (Denmark)

    1996-01-01

    A sound source comprising a loudspeaker (6) and a hollow coupler (4) with an open inlet which communicates with and is closed by the loudspeaker (6) and an open outlet, said coupler (4) comprising rigid walls which cannot respond to the sound pressures produced by the loudspeaker (6). According...

  11. Hamiltonian Algorithm Sound Synthesis

    OpenAIRE

    大矢, 健一

    2013-01-01

    Hamiltonian Algorithm (HA) is an algorithm for searching solutions is optimization problems. This paper introduces a sound synthesis technique using Hamiltonian Algorithm and shows a simple example. "Hamiltonian Algorithm Sound Synthesis" uses phase transition effect in HA. Because of this transition effect, totally new waveforms are produced.

  12. Poetry Pages. Sound Effects.

    Science.gov (United States)

    Fina, Allan de

    1992-01-01

    Explains how elementary teachers can help students understand onomatopoeia, suggesting that they define onomatopoeia, share examples of it, read poems and have students discuss onomatopoeic words, act out common household sounds, write about sound effects, and create choral readings of onomatopoeic poems. Two appropriate poems are included. (SM)

  13. Exploring Noise: Sound Pollution.

    Science.gov (United States)

    Rillo, Thomas J.

    1979-01-01

    Part one of a three-part series about noise pollution and its effects on humans. This section presents the background information for teachers who are preparing a unit on sound. The next issues will offer learning activities for measuring the effects of sound and some references. (SA)

  14. Waveform analysis of sound

    CERN Document Server

    Tohyama, Mikio

    2015-01-01

    What is this sound? What does that sound indicate? These are two questions frequently heard in daily conversation. Sound results from the vibrations of elastic media and in daily life provides informative signals of events happening in the surrounding environment. In interpreting auditory sensations, the human ear seems particularly good at extracting the signal signatures from sound waves. Although exploring auditory processing schemes may be beyond our capabilities, source signature analysis is a very attractive area in which signal-processing schemes can be developed using mathematical expressions. This book is inspired by such processing schemes and is oriented to signature analysis of waveforms. Most of the examples in the book are taken from data of sound and vibrations; however, the methods and theories are mostly formulated using mathematical expressions rather than by acoustical interpretation. This book might therefore be attractive and informative for scientists, engineers, researchers, and graduat...

  15. Sound classification of dwellings

    DEFF Research Database (Denmark)

    Rasmussen, Birgit

    2012-01-01

    National schemes for sound classification of dwellings exist in more than ten countries in Europe, typically published as national standards. The schemes define quality classes reflecting different levels of acoustical comfort. Main criteria concern airborne and impact sound insulation between...... dwellings, facade sound insulation and installation noise. The schemes have been developed, implemented and revised gradually since the early 1990s. However, due to lack of coordination between countries, there are significant discrepancies, and new standards and revisions continue to increase the diversity...... is needed, and a European COST Action TU0901 "Integrating and Harmonizing Sound Insulation Aspects in Sustainable Urban Housing Constructions", has been established and runs 2009-2013, one of the main objectives being to prepare a proposal for a European sound classification scheme with a number of quality...

  16. WE-G-BRD-02: Characterizing Information Loss in a Sparse-Sampling-Based Dynamic MRI Sequence (k-T BLAST) for Lung Motion Monitoring

    International Nuclear Information System (INIS)

    Arai, T; Nofiele, J; Sawant, A

    2015-01-01

    Purpose: Rapid MRI is an attractive, non-ionizing tool for soft-tissue-based monitoring of respiratory motion in thoracic and abdominal radiotherapy. One big challenge is to achieve high temporal resolution while maintaining adequate spatial resolution. K-t BLAST, sparse-sampling and reconstruction sequence based on a-priori information represents a potential solution. In this work, we investigated how much “true” motion information is lost as a-priori information is progressively added for faster imaging. Methods: Lung tumor motions in superior-inferior direction obtained from ten individuals were replayed into an in-house, MRI-compatible, programmable motion platform (50Hz refresh and 100microns precision). Six water-filled 1.5ml tubes were placed on it as fiducial markers. Dynamic marker motion within a coronal slice (FOV: 32×32cm"2, resolution: 0.67×0.67mm"2, slice-thickness: 5mm) was collected on 3.0T body scanner (Ingenia, Philips). Balanced-FFE (TE/TR: 1.3ms/2.5ms, flip-angle: 40degrees) was used in conjunction with k-t BLAST. Each motion was repeated four times as four k-t acceleration factors 1, 2, 5, and 16 (corresponding frame rates were 2.5, 4.7, 9.8, and 19.1Hz, respectively) were compared. For each image set, one average motion trajectory was computed from six marker displacements. Root mean square error (RMS) was used as a metric of spatial accuracy where measured trajectories were compared to original data. Results: Tumor motion was approximately 10mm. The mean(standard deviation) of respiratory rates over ten patients was 0.28(0.06)Hz. Cumulative distributions of tumor motion frequency spectra (0–25Hz) obtained from the patients showed that 90% of motion fell on 3.88Hz or less. Therefore, the frame rate must be a double or higher for accurate monitoring. The RMS errors over patients for k-t factors of 1, 2, 5, and 16 were.10(.04),.17(.04), .21(.06) and.26(.06)mm, respectively. Conclusions: K-t factor of 5 or higher can cover the high

  17. Bilateral Tubercular Lung Abscess in a Diabetic Female

    Directory of Open Access Journals (Sweden)

    N.S Neki

    2017-07-01

    Full Text Available Liquefactive necrosis of the lung tissue caused by microbial infection, lung abscess is characterised by formation of cavities containing necrotic debris. In the vast majority of cases of lung abscess, polymicrobial bacteria can be found with predominance of anaerobes. Mycobacterium has been described as a very rare causative agent of community acquired lung abscess. We are presenting a case of middle aged diabetic female, who had bilateral lung abscesses, aetiology of which was established to be tubercular. Astonishing it may sound; based upon extensive web and library search, it's the first case report on tubercular lung abscess in a diabetic from India, and perhaps from the world itself.

  18. The sound manifesto

    Science.gov (United States)

    O'Donnell, Michael J.; Bisnovatyi, Ilia

    2000-11-01

    Computing practice today depends on visual output to drive almost all user interaction. Other senses, such as audition, may be totally neglected, or used tangentially, or used in highly restricted specialized ways. We have excellent audio rendering through D-A conversion, but we lack rich general facilities for modeling and manipulating sound comparable in quality and flexibility to graphics. We need coordinated research in several disciplines to improve the use of sound as an interactive information channel. Incremental and separate improvements in synthesis, analysis, speech processing, audiology, acoustics, music, etc. will not alone produce the radical progress that we seek in sonic practice. We also need to create a new central topic of study in digital audio research. The new topic will assimilate the contributions of different disciplines on a common foundation. The key central concept that we lack is sound as a general-purpose information channel. We must investigate the structure of this information channel, which is driven by the cooperative development of auditory perception and physical sound production. Particular audible encodings, such as speech and music, illuminate sonic information by example, but they are no more sufficient for a characterization than typography is sufficient for characterization of visual information. To develop this new conceptual topic of sonic information structure, we need to integrate insights from a number of different disciplines that deal with sound. In particular, we need to coordinate central and foundational studies of the representational models of sound with specific applications that illuminate the good and bad qualities of these models. Each natural or artificial process that generates informative sound, and each perceptual mechanism that derives information from sound, will teach us something about the right structure to attribute to the sound itself. The new Sound topic will combine the work of computer

  19. Lung Function Profiles among Individuals with Nonmalignant Asbestos-related Disorders

    Directory of Open Access Journals (Sweden)

    Eun-Kee Park

    2014-12-01

    Conclusion: Lung function measurement differs in individuals with different ARDs. Monitoring of lung function among asbestos-exposed populations is a simple means of facilitating earlier interventions.

  20. Halifax Sound Range Trials (DE0301, EK500)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Radiated sound measurements of vessels are important for monitoring the noise characteristics of fishing and research vessels. A vessel's radiated noise can have...

  1. Sound transmission in porcine thorax through airway insonification

    Science.gov (United States)

    Dai, Zoujun; Mansy, Hansen A.; Henry, Brian M.; Sandler, Richard H.; Balk, Robert A.; Royston, Thomas J.

    2015-01-01

    Many pulmonary injuries and pathologies may lead to structural and functional changes in the lungs resulting in measurable sound transmission changes on the chest surface. Additionally, noninvasive imaging of externally driven mechanical wave motion in the chest (e.g., using magnetic resonance elastography) can provide information about lung structural property changes and, hence, may be of diagnostic value. In the present study, a comprehensive computational simulation (in silico) model was developed to simulate sound wave propagation in the airways, lung, and chest wall under normal and pneumothorax conditions. Experiments were carried out to validate the model. Here, sound waves with frequency content from 50 to 700 Hz were introduced into airways of five porcine subjects via an endotracheal tube, and transmitted waves were measured by scanning laser Doppler vibrometry at the chest wall surface. The computational model predictions of decreased sound transmission with pneumothorax were consistent with experimental measurements. The in silico model can also be used to visualize wave propagation inside and on the chest wall surface for other pulmonary pathologies, which may help in developing and interpreting diagnostic procedures that utilize sound and vibration. PMID:26280512

  2. Sound transmission in porcine thorax through airway insonification.

    Science.gov (United States)

    Peng, Ying; Dai, Zoujun; Mansy, Hansen A; Henry, Brian M; Sandler, Richard H; Balk, Robert A; Royston, Thomas J

    2016-04-01

    Many pulmonary injuries and pathologies may lead to structural and functional changes in the lungs resulting in measurable sound transmission changes on the chest surface. Additionally, noninvasive imaging of externally driven mechanical wave motion in the chest (e.g., using magnetic resonance elastography) can provide information about lung structural property changes and, hence, may be of diagnostic value. In the present study, a comprehensive computational simulation (in silico) model was developed to simulate sound wave propagation in the airways, lung, and chest wall under normal and pneumothorax conditions. Experiments were carried out to validate the model. Here, sound waves with frequency content from 50 to 700 Hz were introduced into airways of five porcine subjects via an endotracheal tube, and transmitted waves were measured by scanning laser Doppler vibrometry at the chest wall surface. The computational model predictions of decreased sound transmission with pneumothorax were consistent with experimental measurements. The in silico model can also be used to visualize wave propagation inside and on the chest wall surface for other pulmonary pathologies, which may help in developing and interpreting diagnostic procedures that utilize sound and vibration.

  3. Lung scintigraphy

    International Nuclear Information System (INIS)

    Dalenz, Roberto.

    1994-01-01

    A review of lung scintigraphy, perfusion scintigraphy with SPECT, lung ventilation SPECT, blood pool SPECT. The procedure of lung perfusion studies, radiopharmaceutical, administration and clinical applications, imaging processing .Results encountered and evaluation criteria after Biello and Pioped. Recommendations and general considerations have been studied about relation of this radiopharmaceutical with other pathologies

  4. Digitizing a sound archive

    DEFF Research Database (Denmark)

    Cone, Louise

    2017-01-01

    Danish and international artists. His methodology left us with a large collection of unique and inspirational time-based media sound artworks that have, until very recently, been inaccessible. Existing on an array of different media formats, such as open reel tapes, 8-track and 4 track cassettes, VHS......In 1990 an artist by the name of William Louis Sørensen was hired by the National Gallery of Denmark to collect important works of art – made from sound. His job was to acquire sound art, but also recordings that captured rare artistic occurrences, music, performances and happenings from both...

  5. Reactor noise monitoring device

    International Nuclear Information System (INIS)

    Yamanaka, Hiroto.

    1990-01-01

    The present invention concerns a reactor noise monitoring device by detecting abnormal sounds in background noises. Vibration sounds detected by accelerometers are applied to a loose parts detector. The detector generates high alarm if there are sudden impact sounds in the background noises and applies output signals to an accumulation device. If there is slight impact sounds in the vicinity of any of the accelerometers, the accumulation device accumulates the abnormal sounds assumed to be generated from an identical site while synchronizing the waveforms for all of the channels. Then, the device outputs signals in which the background noises are cancelled, as detection signals. Therefore, S/N ratio can be improved and the abnormal sounds contained in the background noises can be detected, to thereby improve the accuracy for estimating the position where the abnormal sounds are generated. (I.S.)

  6. Nationwide quality improvement in lung cancer care

    DEFF Research Database (Denmark)

    Jakobsen, Erik Winther; Green, Anders; Oesterlind, Kell

    2013-01-01

    To improve prognosis and quality of lung cancer care the Danish Lung Cancer Group has developed a strategy consisting of national clinical guidelines and a clinical quality and research database. The first edition of our guidelines was published in 1998 and our national lung cancer registry...... was opened for registrations in 2000. This article describes methods and results obtained by multidisciplinary collaboration and illustrates how quality of lung cancer care can be improved by establishing and monitoring result and process indicators....

  7. Sounds of Web Advertising

    DEFF Research Database (Denmark)

    Jessen, Iben Bredahl; Graakjær, Nicolai Jørgensgaard

    2010-01-01

    Sound seems to be a neglected issue in the study of web ads. Web advertising is predominantly regarded as visual phenomena–commercial messages, as for instance banner ads that we watch, read, and eventually click on–but only rarely as something that we listen to. The present chapter presents...... an overview of the auditory dimensions in web advertising: Which kinds of sounds do we hear in web ads? What are the conditions and functions of sound in web ads? Moreover, the chapter proposes a theoretical framework in order to analyse the communicative functions of sound in web advertising. The main...... argument is that an understanding of the auditory dimensions in web advertising must include a reflection on the hypertextual settings of the web ad as well as a perspective on how users engage with web content....

  8. Sound Art Situations

    DEFF Research Database (Denmark)

    Krogh Groth, Sanne; Samson, Kristine

    2017-01-01

    and combine theories from several fields. Aspects of sound art studies, performance studies and contemporary art studies are presented in order to theoretically explore the very diverse dimensions of the two sound art pieces: Visual, auditory, performative, social, spatial and durational dimensions become......This article is an analysis of two sound art performances that took place June 2015 in outdoor public spaces in the social housing area Urbanplanen in Copenhagen, Denmark. The two performances were On the production of a poor acoustics by Brandon LaBelle and Green Interactive Biofeedback...... Environments (GIBE) by Jeremy Woodruff. In order to investigate the complex situation that arises when sound art is staged in such contexts, the authors of this article suggest exploring the events through approaching them as ‘situations’ (Doherty 2009). With this approach it becomes possible to engage...

  9. It sounds good!

    CERN Multimedia

    CERN Bulletin

    2010-01-01

    Both the atmosphere and we ourselves are hit by hundreds of particles every second and yet nobody has ever heard a sound coming from these processes. Like cosmic rays, particles interacting inside the detectors at the LHC do not make any noise…unless you've decided to use the ‘sonification’ technique, in which case you might even hear the Higgs boson sound like music. Screenshot of the first page of the "LHC sound" site. A group of particle physicists, composers, software developers and artists recently got involved in the ‘LHC sound’ project to make the particles at the LHC produce music. Yes…music! The ‘sonification’ technique converts data into sound. “In this way, if you implement the right software you can get really nice music out of the particle tracks”, says Lily Asquith, a member of the ATLAS collaboration and one of the initiators of the project. The ‘LHC...

  10. Sound Visualization and Holography

    Science.gov (United States)

    Kock, Winston E.

    1975-01-01

    Describes liquid surface holograms including their application to medicine. Discusses interference and diffraction phenomena using sound wave scanning techniques. Compares focussing by zone plate to holographic image development. (GH)

  11. Applying cybernetic technology to diagnose human pulmonary sounds.

    Science.gov (United States)

    Chen, Mei-Yung; Chou, Cheng-Han

    2014-06-01

    Chest auscultation is a crucial and efficient method for diagnosing lung disease; however, it is a subjective process that relies on physician experience and the ability to differentiate between various sound patterns. Because the physiological signals composed of heart sounds and pulmonary sounds (PSs) are greater than 120 Hz and the human ear is not sensitive to low frequencies, successfully making diagnostic classifications is difficult. To solve this problem, we constructed various PS recognition systems for classifying six PS classes: vesicular breath sounds, bronchial breath sounds, tracheal breath sounds, crackles, wheezes, and stridor sounds. First, we used a piezoelectric microphone and data acquisition card to acquire PS signals and perform signal preprocessing. A wavelet transform was used for feature extraction, and the PS signals were decomposed into frequency subbands. Using a statistical method, we extracted 17 features that were used as the input vectors of a neural network. We proposed a 2-stage classifier combined with a back-propagation (BP) neural network and learning vector quantization (LVQ) neural network, which improves classification accuracy by using a haploid neural network. The receiver operating characteristic (ROC) curve verifies the high performance level of the neural network. To expand traditional auscultation methods, we constructed various PS diagnostic systems that can correctly classify the six common PSs. The proposed device overcomes the lack of human sensitivity to low-frequency sounds and various PS waves, characteristic values, and a spectral analysis charts are provided to elucidate the design of the human-machine interface.

  12. Lung density

    DEFF Research Database (Denmark)

    Garnett, E S; Webber, C E; Coates, G

    1977-01-01

    The density of a defined volume of the human lung can be measured in vivo by a new noninvasive technique. A beam of gamma-rays is directed at the lung and, by measuring the scattered gamma-rays, lung density is calculated. The density in the lower lobe of the right lung in normal man during quiet...... breathing in the sitting position ranged from 0.25 to 0.37 g.cm-3. Subnormal values were found in patients with emphsema. In patients with pulmonary congestion and edema, lung density values ranged from 0.33 to 0.93 g.cm-3. The lung density measurement correlated well with the findings in chest radiographs...... but the lung density values were more sensitive indices. This was particularly evident in serial observations of individual patients....

  13. What Is Lung Cancer?

    Science.gov (United States)

    ... Shareable Graphics Infographics “African-American Men and Lung Cancer” “Lung Cancer Is the Biggest Cancer Killer in Both ... starts in the lungs, it is called lung cancer. Lung cancer begins in the lungs and may spread ...

  14. Abscess in the Lungs

    Science.gov (United States)

    ... Home Lung and Airway Disorders Abscess in the Lungs Abscess in the Lungs Causes Symptoms Diagnosis Treatment Resources ... here for the Professional Version Abscess in the Lungs Abscess in the Lungs A lung abscess is a ...

  15. 75 FR 16159 - Prince William Sound Regional Citizens' Advisory Council (PWSRCAC) Charter Renewal

    Science.gov (United States)

    2010-03-31

    ... DEPARTMENT OF HOMELAND SECURITY Coast Guard [USCG-2010-0121] Prince William Sound Regional... the Prince William Sound Regional Citizens' Advisory Council (PWSRCAC) as an alternative voluntary advisory group for Prince William Sound, Alaska. This certification allows the PWSRCAC to monitor the...

  16. 77 FR 19301 - Prince William Sound Regional Citizens' Advisory Council Charter Renewal

    Science.gov (United States)

    2012-03-30

    ... DEPARTMENT OF HOMELAND SECURITY Coast Guard [USCG-2012-0099] Prince William Sound Regional... Prince William Sound Regional Citizens' Advisory Council (PWSRCAC) as an alternative voluntary advisory group for Prince William Sound, Alaska. This certification allows the PWSRCAC to monitor the activities...

  17. The Textile Form of Sound

    DEFF Research Database (Denmark)

    Bendixen, Cecilie

    Sound is a part of architecture, and sound is complex. Upon this, sound is invisible. How is it then possible to design visual objects that interact with the sound? This paper addresses the problem of how to get access to the complexity of sound and how to make textile material revealing the form...... goemetry by analysing the sound pattern at a specific spot. This analysis is done theoretically with algorithmic systems and practical with waves in water. The paper describes the experiments and the findings, and explains how an analysis of sound can be catched in a textile form....

  18. Comparison of recording of pericarditis and lung disorders at routine meat inspection with findings at systematic health monitoring in Danish finisher pigs

    DEFF Research Database (Denmark)

    Nielsen, Søren Saxmose; Nielsen, Gitte Blach; Denwood, Matt

    2015-01-01

    purpose that is required of them. Routine meat inspection data were originally collected with the purpose of safeguarding food, but have been re-tasked to also include animal welfare assessment. The objective of the present study was to compare the recording of pericarditis, pleuritis and lungs......). Conclusions Overall, the results suggest that the correlation between findings at RMI and SHM was moderate for pleuritis and lungs with lesions, but poor for pericarditis. The latter could partly be explained by the type of meat inspection conducted at the abattoir. We conclude that caution should be used...

  19. Offshore dredger sound: source levels, sound maps and risk assessment (abstract)

    NARCIS (Netherlands)

    Jong, C.A.F. de; Ainslie, M.A.; Heinis, F.; Janmaat, J.

    2013-01-01

    The Port of Rotterdam is expanding to meet the growing demand to accommodate large cargo vessels. One of the licensing conditions was the monitoring of the underwater sound produced during its construction, with an emphasis on the establishment of acoustic source levels of the Trailing Suction

  20. Lung Cancer

    International Nuclear Information System (INIS)

    Maghfoor, Irfan; Perry, M.C.

    2005-01-01

    Lung cancer is the leading cause of cancer-related mortality. Since tobacco smoking is the cause in vast majority of cases, the incidence of lung cancer is expected to rise in those countries with high or rising incidence of tobacco smoking. Even though population at a risk of developing lung cancer are easily identified, mass screening for lung cancer is not supported by currently available evidence. In case of non-small cell lung cancer, a cure may be possible with surgical resection followed by post-operative chemotherapy in those diagnosed at an early stage. A small minority of patients who present with locally advanced disease may also benefit from preoperative chemotherapy and/or radiation therapy to down stage the tumor to render it potentially operable. In a vast majority of patients, however, lung cancer presents at an advanced stage and a cure is not possible with currently available therapeutic strategies. Similarly small cell lung cancer confined to one hemi-thorax may be curable with a combination of chemotherapy and thoracic irradiation followed by prophylactic cranial irradiation, if complete remission is achieved at the primary site. Small cell lung cancer that is spread beyond the confines of one hemi-thorax is however, considered incurable. In this era of molecular targeted therapies, new agents are constantly undergoing pre-clinical and clinical testing with the aim of targeting the molecular pathways thought to involved in etiology and pathogenesis of lung cancer. (author)

  1. Sound & The Society

    DEFF Research Database (Denmark)

    Schulze, Holger

    2014-01-01

    How are those sounds you hear right now socially constructed and evaluated, how are they architecturally conceptualized and how dependant on urban planning, industrial developments and political decisions are they really? How is your ability to hear intertwined with social interactions and their ...... and their professional design? And how is listening and sounding a deeply social activity – constructing our way of living together in cities as well as in apartment houses? A radio feature with Nina Backmann, Jochen Bonz, Stefan Krebs, Esther Schelander & Holger Schulze......How are those sounds you hear right now socially constructed and evaluated, how are they architecturally conceptualized and how dependant on urban planning, industrial developments and political decisions are they really? How is your ability to hear intertwined with social interactions...

  2. Urban Sound Interfaces

    DEFF Research Database (Denmark)

    Breinbjerg, Morten

    2012-01-01

    This paper draws on the theories of Michel de Certeau and Gaston Bachelard to discuss how media architecture, in the form of urban sound interfaces, can help us perceive the complexity of the spaces we inhabit, by exploring the history and the narratives of the places in which we live. In this pa......This paper draws on the theories of Michel de Certeau and Gaston Bachelard to discuss how media architecture, in the form of urban sound interfaces, can help us perceive the complexity of the spaces we inhabit, by exploring the history and the narratives of the places in which we live....... In this paper, three sound works are discussed in relation to the iPod, which is considered as a more private way to explore urban environments, and as a way to control the individual perception of urban spaces....

  3. Predicting outdoor sound

    CERN Document Server

    Attenborough, Keith; Horoshenkov, Kirill

    2014-01-01

    1. Introduction  2. The Propagation of Sound Near Ground Surfaces in a Homogeneous Medium  3. Predicting the Acoustical Properties of Outdoor Ground Surfaces  4. Measurements of the Acoustical Properties of Ground Surfaces and Comparisons with Models  5. Predicting Effects of Source Characteristics on Outdoor Sound  6. Predictions, Approximations and Empirical Results for Ground Effect Excluding Meteorological Effects  7. Influence of Source Motion on Ground Effect and Diffraction  8. Predicting Effects of Mixed Impedance Ground  9. Predicting the Performance of Outdoor Noise Barriers  10. Predicting Effects of Vegetation, Trees and Turbulence  11. Analytical Approximations including Ground Effect, Refraction and Turbulence  12. Prediction Schemes  13. Predicting Sound in an Urban Environment.

  4. Sound & The Senses

    DEFF Research Database (Denmark)

    Schulze, Holger

    2012-01-01

    How are those sounds you hear right now technically generated and post-produced, how are they aesthetically conceptualized and how culturally dependant are they really? How is your ability to hear intertwined with all the other senses and their cultural, biographical and technological constructio...... over time? And how is listening and sounding a deeply social activity – constructing our way of living together in cities as well as in apartment houses? A radio feature with Jonathan Sterne, AGF a.k.a Antye Greie, Jens Gerrit Papenburg & Holger Schulze....

  5. Handbook for sound engineers

    CERN Document Server

    Ballou, Glen

    2013-01-01

    Handbook for Sound Engineers is the most comprehensive reference available for audio engineers. All audio topics are explored: if you work on anything related to audio you should not be without this book! The 4th edition of this trusted reference has been updated to reflect changes in the industry since the publication of the 3rd edition in 2002 -- including new technologies like software-based recording systems such as Pro Tools and Sound Forge; digital recording using MP3, wave files and others; mobile audio devices such as iPods and MP3 players. Over 40 topic

  6. Sound for digital video

    CERN Document Server

    Holman, Tomlinson

    2013-01-01

    Achieve professional quality sound on a limited budget! Harness all new, Hollywood style audio techniques to bring your independent film and video productions to the next level.In Sound for Digital Video, Second Edition industry experts Tomlinson Holman and Arthur Baum give you the tools and knowledge to apply recent advances in audio capture, video recording, editing workflow, and mixing to your own film or video with stunning results. This fresh edition is chockfull of techniques, tricks, and workflow secrets that you can apply to your own projects from preproduction

  7. Beacons of Sound

    DEFF Research Database (Denmark)

    Knakkergaard, Martin

    2018-01-01

    The chapter discusses expectations and imaginations vis-à-vis the concert hall of the twenty-first century. It outlines some of the central historical implications of western culture’s haven for sounding music. Based on the author’s study of the Icelandic concert-house Harpa, the chapter considers...... how these implications, together with the prime mover’s visions, have been transformed as private investors and politicians took over. The chapter furthermore investigates the objectives regarding musical sound and the far-reaching demands concerning acoustics that modern concert halls are required...

  8. Neuroplasticity beyond sounds

    DEFF Research Database (Denmark)

    Reybrouck, Mark; Brattico, Elvira

    2015-01-01

    Capitalizing from neuroscience knowledge on how individuals are affected by the sound environment, we propose to adopt a cybernetic and ecological point of view on the musical aesthetic experience, which includes subprocesses, such as feature extraction and integration, early affective reactions...... and motor actions, style mastering and conceptualization, emotion and proprioception, evaluation and preference. In this perspective, the role of the listener/composer/performer is seen as that of an active "agent" coping in highly individual ways with the sounds. The findings concerning the neural...

  9. Eliciting Sound Memories.

    Science.gov (United States)

    Harris, Anna

    2015-11-01

    Sensory experiences are often considered triggers of memory, most famously a little French cake dipped in lime blossom tea. Sense memory can also be evoked in public history research through techniques of elicitation. In this article I reflect on different social science methods for eliciting sound memories such as the use of sonic prompts, emplaced interviewing, and sound walks. I include examples from my research on medical listening. The article considers the relevance of this work for the conduct of oral histories, arguing that such methods "break the frame," allowing room for collaborative research connections and insights into the otherwise unarticulatable.

  10. SoleSound

    DEFF Research Database (Denmark)

    Zanotto, Damiano; Turchet, Luca; Boggs, Emily Marie

    2014-01-01

    This paper introduces the design of SoleSound, a wearable system designed to deliver ecological, audio-tactile, underfoot feedback. The device, which primarily targets clinical applications, uses an audio-tactile footstep synthesis engine informed by the readings of pressure and inertial sensors...... embedded in the footwear to integrate enhanced feedback modalities into the authors' previously developed instrumented footwear. The synthesis models currently implemented in the SoleSound simulate different ground surface interactions. Unlike similar devices, the system presented here is fully portable...

  11. Equipment abnormality monitoring device

    International Nuclear Information System (INIS)

    Ando, Yasumasa

    1991-01-01

    When an operator hears sounds in a plantsite, the operator compares normal sounds of equipment which he previously heard and remembered with sounds he actually hears, to judge if they are normal or abnormal. According to the method, there is a worry that abnormal conditions can not be appropriately judged in a case where the number of objective equipments is increased and in a case that the sounds are changed gradually slightly. Then, the device of the present invention comprises a plurality of monitors for monitoring the operation sound of equipments, a recording/reproducing device for recording and reproducing the signals, a selection device for selecting the reproducing signals among the recorded signals, an acoustic device for converting the signals to sounds, a switching device for switching the signals to be transmitted to the acoustic device between to signals of the monitor and the recording/reproducing signals. The abnormality of the equipments can be determined easily by comparing the sounds representing the operation conditions of equipments for controlling the plant operation and the sounds recorded in their normal conditions. (N.H.)

  12. Lung Cancer

    Science.gov (United States)

    Lung cancer is one of the most common cancers in the world. It is a leading cause of cancer death in men and women in the United States. Cigarette smoking causes most lung cancers. The more cigarettes you smoke per day and ...

  13. Sound Symbolism in Basic Vocabulary

    Directory of Open Access Journals (Sweden)

    Søren Wichmann

    2010-04-01

    Full Text Available The relationship between meanings of words and their sound shapes is to a large extent arbitrary, but it is well known that languages exhibit sound symbolism effects violating arbitrariness. Evidence for sound symbolism is typically anecdotal, however. Here we present a systematic approach. Using a selection of basic vocabulary in nearly one half of the world’s languages we find commonalities among sound shapes for words referring to same concepts. These are interpreted as due to sound symbolism. Studying the effects of sound symbolism cross-linguistically is of key importance for the understanding of language evolution.

  14. ABOUT SOUNDS IN VIDEO GAMES

    Directory of Open Access Journals (Sweden)

    Denikin Anton A.

    2012-12-01

    Full Text Available The article considers the aesthetical and practical possibilities for sounds (sound design in video games and interactive applications. Outlines the key features of the game sound, such as simulation, representativeness, interactivity, immersion, randomization, and audio-visuality. The author defines the basic terminology in study of game audio, as well as identifies significant aesthetic differences between film sounds and sounds in video game projects. It is an attempt to determine the techniques of art analysis for the approaches in study of video games including aesthetics of their sounds. The article offers a range of research methods, considering the video game scoring as a contemporary creative practice.

  15. Exploring Sound with Insects

    Science.gov (United States)

    Robertson, Laura; Meyer, John R.

    2010-01-01

    Differences in insect morphology and movement during singing provide a fascinating opportunity for students to investigate insects while learning about the characteristics of sound. In the activities described here, students use a free online computer software program to explore the songs of the major singing insects and experiment with making…

  16. Second sound tracking system

    Science.gov (United States)

    Yang, Jihee; Ihas, Gary G.; Ekdahl, Dan

    2017-10-01

    It is common that a physical system resonates at a particular frequency, whose frequency depends on physical parameters which may change in time. Often, one would like to automatically track this signal as the frequency changes, measuring, for example, its amplitude. In scientific research, one would also like to utilize the standard methods, such as lock-in amplifiers, to improve the signal to noise ratio. We present a complete He ii second sound system that uses positive feedback to generate a sinusoidal signal of constant amplitude via automatic gain control. This signal is used to produce temperature/entropy waves (second sound) in superfluid helium-4 (He ii). A lock-in amplifier limits the oscillation to a desirable frequency and demodulates the received sound signal. Using this tracking system, a second sound signal probed turbulent decay in He ii. We present results showing that the tracking system is more reliable than those of a conventional fixed frequency method; there is less correlation with temperature (frequency) fluctuation when the tracking system is used.

  17. See This Sound

    DEFF Research Database (Denmark)

    Kristensen, Thomas Bjørnsten

    2009-01-01

    Anmeldelse af udstillingen See This Sound på Lentos Kunstmuseum Linz, Østrig, som markerer den foreløbige kulmination på et samarbejde mellem Lentos Kunstmuseum og Ludwig Boltzmann Institute Media.Art.Research. Udover den konkrete udstilling er samarbejdet tænkt som en ambitiøs, tværfaglig...

  18. Photoacoustic Sounds from Meteors.

    Energy Technology Data Exchange (ETDEWEB)

    Spalding, Richard E. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Tencer, John [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Sweatt, William C. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Hogan, Roy E. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Boslough, Mark B. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Spurny, Pavel [Academy of Sciences of the Czech Republic (ASCR), Prague (Czech Republic)

    2015-03-01

    High-speed photometric observations of meteor fireballs have shown that they often produce high-amplitude light oscillations with frequency components in the kHz range, and in some cases exhibit strong millisecond flares. We built a light source with similar characteristics and illuminated various materials in the laboratory, generating audible sounds. Models suggest that light oscillations and pulses can radiatively heat dielectric materials, which in turn conductively heats the surrounding air on millisecond timescales. The sound waves can be heard if the illuminated material is sufficiently close to the observer’s ears. The mechanism described herein may explain many reports of meteors that appear to be audible while they are concurrently visible in the sky and too far away for sound to have propagated to the observer. This photoacoustic (PA) explanation provides an alternative to electrophonic (EP) sounds hypothesized to arise from electromagnetic coupling of plasma oscillation in the meteor wake to natural antennas in the vicinity of an observer.

  19. Sound of Stockholm

    DEFF Research Database (Denmark)

    Groth, Sanne Krogh

    2013-01-01

    Med sine kun 4 år bag sig er Sound of Stockholm relativt ny i det internationale festival-landskab. Festivalen er efter sigende udsprunget af en større eller mindre frustration over, at den svenske eksperimentelle musikscenes forskellige foreninger og organisationer gik hinanden bedene, og...

  20. Making Sense of Sound

    Science.gov (United States)

    Menon, Deepika; Lankford, Deanna

    2016-01-01

    From the earliest days of their lives, children are exposed to all kinds of sound, from soft, comforting voices to the frightening rumble of thunder. Consequently, children develop their own naïve explanations largely based upon their experiences with phenomena encountered every day. When new information does not support existing conceptions,…

  1. The Sounds of Metal

    DEFF Research Database (Denmark)

    Grund, Cynthia M.

    2015-01-01

    Two, I propose that this framework allows for at least a theoretical distinction between the way in which extreme metal – e.g. black metal, doom metal, funeral doom metal, death metal – relates to its sound as music and the way in which much other music may be conceived of as being constituted...

  2. The Universe of Sound

    CERN Multimedia

    CERN. Geneva

    2013-01-01

    Sound Scultor, Bill Fontana, the second winner of the Prix Ars Electronica Collide@CERN residency award, and his science inspiration partner, CERN cosmologist Subodh Patil, present their work in art and science at the CERN Globe of Science and Innovation on 4 July 2013 at 19:00.

  3. Urban Sound Ecologies

    DEFF Research Database (Denmark)

    Groth, Sanne Krogh; Samson, Kristine

    2013-01-01

    . The article concludes that the ways in which recent sound installations work with urban ecologies vary. While two of the examples blend into the urban environment, the other transfers the concert format and its mode of listening to urban space. Last, and in accordance with recent soundscape research, we point...

  4. Lung Cancer Screening

    Science.gov (United States)

    ... factors increase or decrease the risk of lung cancer. Lung cancer is a disease in which malignant (cancer) ... following PDQ summaries for more information about lung cancer: Lung Cancer Prevention Non-Small Cell Lung Cancer Treatment ...

  5. Sounds of Space

    Science.gov (United States)

    Gurnett, D. A.

    2005-12-01

    Starting in the early 1960s, spacecraft-borne plasma wave instruments revealed that space is filled with an astonishing variety of radio and plasma wave sounds, which have come to be called "sounds of space." For over forty years these sounds have been collected and played to a wide variety of audiences, often as the result of press conferences or press releases involving various NASA projects for which the University of Iowa has provided plasma wave instruments. This activity has led to many interviews on local and national radio programs, and occasionally on programs haviang world-wide coverage, such as the BBC. As a result of this media coverage, we have been approached many times by composers requesting copies of our space sounds for use in their various projects, many of which involve electronic synthesis of music. One of these collaborations led to "Sun Rings," which is a musical event produced by the Kronos Quartet that has played to large audiences all over the world. With the availability of modern computer graphic techniques we have recently been attempting to integrate some of these sound of space into an educational audio/video web site that illustrates the scientific principles involved in the origin of space plasma waves. Typically I try to emphasize that a substantial gas pressure exists everywhere in space in the form of an ionized gas called a plasma, and that this plasma can lead to a wide variety of wave phenomenon. Examples of some of this audio/video material will be presented.

  6. Parameterizing Sound: Design Considerations for an Environmental Sound Database

    Science.gov (United States)

    2015-04-01

    associated with, or produced by, a physical event or human activity and 2) sound sources that are common in the environment. Reproductions or sound...Rogers S. Confrontation naming of environmental sounds. Journal of Clinical and Experimental Neuropsychology . 2000;22(6):830–864. 14 VanDerveer NJ

  7. Monitoring changes in quality of life in patients with lung cancer under treatment with chemotherapy and co administration of zoledronic acid by using specialized questionnaires.

    Science.gov (United States)

    Tremmas, Ioannis; Petsatodis, George; Potoupnis, Michael; Laskou, Stella; Giannakidis, Dimitrios; Mantalovas, Stylianos; Koulouris, Charilaos; Katsaounis, Athanasios; Pavlidis, Efstathios; Amaniti, Aikaterini; Huang, Haidong; Bai, Chong; Shi, Dongchen; Dardas, Athanasios; Zarogoulidis, Paul; Sardeli, Chrisanthi; Konstantinou, Fotis; Katsikogiannis, Nikolaos; Zarogoulidis, Konstantinos; Karapantzos, Ilias; Karapantzou, Chrysanthi; Shen, Xiaping; Kesisoglou, Isaak; Sapalidis, Konstantinos

    2018-01-01

    Background: Due to the severity of the primary disease in patients with lung cancer, quality of life (QoL) is often overlooked. Factors that form QoL should be taken in consideration when planning the appropriate treatment and determining therapy targets, because of the increasing frequency of bone metastasis leading to high levels of pain. Purpose of this study is to assess quality of life in patients with lung cancer, before and after treatment combined with zoledronic acid. Methods and materials: QoL was assessed in 80 patients (49 males-31 females), of which 45 developed bone metastasis. Prior and post treatment (with co administration of zoledronic acid) seven reliable scales: Pittsburgh Sleep Quality index (PSQI), Epworth Sleeping Scale (ess), Dyspnea Scale (ds), Fatigue Severity Scale (FSS), Brief Pain Inventory (BPI), Fact-G scale for sleep quality and EQ-5D for general health condition. Results: Statistically positive correlations were verified between PSQI-DS, PSQI-FSS, BPI-ESS, DS-FSS, DS-BPI and BPI-FSS (pbetterment in quality of life was marked (p<0,001). Although significant decrease in fatigue levels was observed (p<0,001) there has been an increase in dyspnea symptoms (p<0,001). Conclusions: Significant improvement was apparent when zoledronic acid was co administered in any treatment in patients with lung cancer. Sleep quality, fatigue and pain parameters also improved, with no positive impact on the symptoms of dyspnea.

  8. Lung abscess

    International Nuclear Information System (INIS)

    Ha, H.K.; Kang, M.W.; Park, J.M.; Yang, W.J.; Shinn, K.S.; Bahk, Y.W.

    1993-01-01

    Lung abscess was successfully treated with percutaneous drainage in 5 of 6 patients. Complete abscess resolution occurred in 4 patients, partial resolution in one, and no response in one. The duration of drainage ranged from 7 to 18 days (mean 15.5 days) in successful cases. The failure of drainage in one neurologicall impaired patient was attributed to persistent aspiration. In 2 patients, concurrent pleural empyema was also cured. CT provided the anatomic details necessary for choosing the puncture site and avoiding puncture of the lung parenchyma. Percutaneous catheter drainage is a safe and effective method for treating lung abscess. (orig.)

  9. Product sounds : Fundamentals and application

    NARCIS (Netherlands)

    Ozcan-Vieira, E.

    2008-01-01

    Products are ubiquitous, so are the sounds emitted by products. Product sounds influence our reasoning, emotional state, purchase decisions, preference, and expectations regarding the product and the product's performance. Thus, auditory experience elicited by product sounds may not be just about

  10. Sonic mediations: body, sound, technology

    NARCIS (Netherlands)

    Birdsall, C.; Enns, A.

    2008-01-01

    Sonic Mediations: Body, Sound, Technology is a collection of original essays that represents an invaluable contribution to the burgeoning field of sound studies. While sound is often posited as having a bridging function, as a passive in-between, this volume invites readers to rethink the concept of

  11. System for actively reducing sound

    NARCIS (Netherlands)

    Berkhoff, Arthur P.

    2005-01-01

    A system for actively reducing sound from a primary noise source, such as traffic noise, comprising: a loudspeaker connector for connecting to at least one loudspeaker for generating anti-sound for reducing said noisy sound; a microphone connector for connecting to at least a first microphone placed

  12. Sound Is Sound: Film Sound Techniques and Infrasound Data Array Processing

    Science.gov (United States)

    Perttu, A. B.; Williams, R.; Taisne, B.; Tailpied, D.

    2017-12-01

    A multidisciplinary collaboration between earth scientists and a sound designer/composer was established to explore the possibilities of audification analysis of infrasound array data. Through the process of audification of the infrasound we began to experiment with techniques and processes borrowed from cinema to manipulate the noise content of the signal. The results of this posed the question: "Would the accuracy of infrasound data array processing be enhanced by employing these techniques?". So a new area of research was born from this collaboration and highlights the value of these interactions and the unintended paths that can occur from them. Using a reference event database, infrasound data were processed using these new techniques and the results were compared with existing techniques to asses if there was any improvement to detection capability for the array. With just under one thousand volcanoes, and a high probability of eruption, Southeast Asia offers a unique opportunity to develop and test techniques for regional monitoring of volcanoes with different technologies. While these volcanoes are monitored locally (e.g. seismometer, infrasound, geodetic and geochemistry networks) and remotely (e.g. satellite and infrasound), there are challenges and limitations to the current monitoring capability. Not only is there a high fraction of cloud cover in the region, making plume observation more difficult via satellite, there have been examples of local monitoring networks and telemetry being destroyed early in the eruptive sequence. The success of local infrasound studies to identify explosions at volcanoes, and calculate plume heights from these signals, has led to an interest in retrieving source parameters for the purpose of ash modeling with a regional network independent of cloud cover.

  13. Sound segregation via embedded repetition is robust to inattention.

    Science.gov (United States)

    Masutomi, Keiko; Barascud, Nicolas; Kashino, Makio; McDermott, Josh H; Chait, Maria

    2016-03-01

    The segregation of sound sources from the mixture of sounds that enters the ear is a core capacity of human hearing, but the extent to which this process is dependent on attention remains unclear. This study investigated the effect of attention on the ability to segregate sounds via repetition. We utilized a dual task design in which stimuli to be segregated were presented along with stimuli for a "decoy" task that required continuous monitoring. The task to assess segregation presented a target sound 10 times in a row, each time concurrent with a different distractor sound. McDermott, Wrobleski, and Oxenham (2011) demonstrated that repetition causes the target sound to be segregated from the distractors. Segregation was queried by asking listeners whether a subsequent probe sound was identical to the target. A control task presented similar stimuli but probed discrimination without engaging segregation processes. We present results from 3 different decoy tasks: a visual multiple object tracking task, a rapid serial visual presentation (RSVP) digit encoding task, and a demanding auditory monitoring task. Load was manipulated by using high- and low-demand versions of each decoy task. The data provide converging evidence of a small effect of attention that is nonspecific, in that it affected the segregation and control tasks to a similar extent. In all cases, segregation performance remained high despite the presence of a concurrent, objectively demanding decoy task. The results suggest that repetition-based segregation is robust to inattention. (c) 2016 APA, all rights reserved).

  14. Wood for sound.

    Science.gov (United States)

    Wegst, Ulrike G K

    2006-10-01

    The unique mechanical and acoustical properties of wood and its aesthetic appeal still make it the material of choice for musical instruments and the interior of concert halls. Worldwide, several hundred wood species are available for making wind, string, or percussion instruments. Over generations, first by trial and error and more recently by scientific approach, the most appropriate species were found for each instrument and application. Using material property charts on which acoustic properties such as the speed of sound, the characteristic impedance, the sound radiation coefficient, and the loss coefficient are plotted against one another for woods. We analyze and explain why spruce is the preferred choice for soundboards, why tropical species are favored for xylophone bars and woodwind instruments, why violinists still prefer pernambuco over other species as a bow material, and why hornbeam and birch are used in piano actions.

  15. Sounds in context

    DEFF Research Database (Denmark)

    Weed, Ethan

    A sound is never just a sound. It is becoming increasingly clear that auditory processing is best thought of not as a one-way afferent stream, but rather as an ongoing interaction between interior processes and the environment. Even the earliest stages of auditory processing in the nervous system...... time-course of contextual influence on auditory processing in three different paradigms: a simple mismatch negativity paradigm with tones of differing pitch, a multi-feature mismatch negativity paradigm in which tones were embedded in a complex musical context, and a cross-modal paradigm, in which...... auditory processing of emotional speech was modulated by an accompanying visual context. I then discuss these results in terms of their implication for how we conceive of the auditory processing stream....

  16. Sound for Health

    CERN Multimedia

    CERN. Geneva

    2016-01-01

    From astronomy to biomedical sciences: music and sound as tools for scientific investigation Music and science are probably two of the most intrinsically linked disciplines in the spectrum of human knowledge. Science and technology have revolutionised the way artists work, interact, and create. The impact of innovative materials, new communication media, more powerful computers, and faster networks on the creative process is evident: we all can become artists in the digital era. What is less known, is that arts, and music in particular, are having a profound impact the way scientists operate, and think. From the early experiments by Kepler to the modern data sonification applications in medicine – sound and music are playing an increasingly crucial role in supporting science and driving innovation. In this talk. Dr. Domenico Vicinanza will be highlighting the complementarity and the natural synergy between music and science, with specific reference to biomedical sciences. Dr. Vicinanza will take t...

  17. Sound in Ergonomics

    Directory of Open Access Journals (Sweden)

    Jebreil Seraji

    1999-03-01

    Full Text Available The word of “Ergonomics “is composed of two separate parts: “Ergo” and” Nomos” and means the Human Factors Engineering. Indeed, Ergonomics (or human factors is the scientific discipline concerned with the understanding of interactions among humans and other elements of a system, and the profession that applies theory, principles, data and methods to design in order to optimize human well-being and overall system performance. It has applied different sciences such as Anatomy and physiology, anthropometry, engineering, psychology, biophysics and biochemistry from different ergonomics purposes. Sound when is referred as noise pollution can affect such balance in human life. The industrial noise caused by factories, traffic jam, media, and modern human activity can affect the health of the society.Here we are aimed at discussing sound from an ergonomic point of view.

  18. Pitch Based Sound Classification

    DEFF Research Database (Denmark)

    Nielsen, Andreas Brinch; Hansen, Lars Kai; Kjems, U

    2006-01-01

    A sound classification model is presented that can classify signals into music, noise and speech. The model extracts the pitch of the signal using the harmonic product spectrum. Based on the pitch estimate and a pitch error measure, features are created and used in a probabilistic model with soft......-max output function. Both linear and quadratic inputs are used. The model is trained on 2 hours of sound and tested on publicly available data. A test classification error below 0.05 with 1 s classification windows is achieved. Further more it is shown that linear input performs as well as a quadratic......, and that even though classification gets marginally better, not much is achieved by increasing the window size beyond 1 s....

  19. Airspace: Antarctic Sound Transmission

    OpenAIRE

    Polli, Andrea

    2009-01-01

    This paper investigates how sound transmission can contribute to the public understanding of climate change within the context of the Poles. How have such transmission-based projects developed specifically in the Arctic and Antarctic, and how do these works create alternative pathways in order to help audiences better understand climate change? The author has created the media project Sonic Antarctica from a personal experience of the Antarctic. The work combines soundscape recordings and son...

  20. Lung cancer

    Science.gov (United States)

    ... causing chemicals such as uranium, beryllium, vinyl chloride, nickel chromates, coal products, mustard gas, chloromethyl ethers, gasoline, and diesel exhaust Exposure to radon gas Family history of lung cancer ...

  1. Lung surgery

    Science.gov (United States)

    ... are thoracotomy and video-assisted thoracoscopic surgery (VATS). Robotic surgery may also be used. Lung surgery using ... Center-Shreveport, Shreveport, LA. Review provided by VeriMed Healthcare Network. Also reviewed by David Zieve, MD, MHA, ...

  2. Swallowing sound detection using hidden markov modeling of recurrence plot features

    International Nuclear Information System (INIS)

    Aboofazeli, Mohammad; Moussavi, Zahra

    2009-01-01

    Automated detection of swallowing sounds in swallowing and breath sound recordings is of importance for monitoring purposes in which the recording durations are long. This paper presents a novel method for swallowing sound detection using hidden Markov modeling of recurrence plot features. Tracheal sound recordings of 15 healthy and nine dysphagic subjects were studied. The multidimensional state space trajectory of each signal was reconstructed using the Taken method of delays. The sequences of three recurrence plot features of the reconstructed trajectories (which have shown discriminating capability between swallowing and breath sounds) were modeled by three hidden Markov models. The Viterbi algorithm was used for swallowing sound detection. The results were validated manually by inspection of the simultaneously recorded airflow signal and spectrogram of the sounds, and also by auditory means. The experimental results suggested that the performance of the proposed method using hidden Markov modeling of recurrence plot features was superior to the previous swallowing sound detection methods.

  3. Swallowing sound detection using hidden markov modeling of recurrence plot features

    Energy Technology Data Exchange (ETDEWEB)

    Aboofazeli, Mohammad [Faculty of Engineering, Department of Electrical and Computer Engineering, University of Manitoba, Winnipeg, Manitoba, R3T 5V6 (Canada)], E-mail: umaboofa@cc.umanitoba.ca; Moussavi, Zahra [Faculty of Engineering, Department of Electrical and Computer Engineering, University of Manitoba, Winnipeg, Manitoba, R3T 5V6 (Canada)], E-mail: mousavi@ee.umanitoba.ca

    2009-01-30

    Automated detection of swallowing sounds in swallowing and breath sound recordings is of importance for monitoring purposes in which the recording durations are long. This paper presents a novel method for swallowing sound detection using hidden Markov modeling of recurrence plot features. Tracheal sound recordings of 15 healthy and nine dysphagic subjects were studied. The multidimensional state space trajectory of each signal was reconstructed using the Taken method of delays. The sequences of three recurrence plot features of the reconstructed trajectories (which have shown discriminating capability between swallowing and breath sounds) were modeled by three hidden Markov models. The Viterbi algorithm was used for swallowing sound detection. The results were validated manually by inspection of the simultaneously recorded airflow signal and spectrogram of the sounds, and also by auditory means. The experimental results suggested that the performance of the proposed method using hidden Markov modeling of recurrence plot features was superior to the previous swallowing sound detection methods.

  4. Sound exposure during outdoor music festivals

    Directory of Open Access Journals (Sweden)

    Tron V Tronstad

    2016-01-01

    Full Text Available Most countries have guidelines to regulate sound exposure at concerts and music festivals. These guidelines limit the allowed sound pressure levels and the concert/festival’s duration. In Norway, where there is such a guideline, it is up to the local authorities to impose the regulations. The need to prevent hearing-loss among festival participants is self-explanatory, but knowledge of the actual dose received by visitors is extremely scarce. This study looks at two Norwegian music festivals where only one was regulated by the Norwegian guideline for concert and music festivals. At each festival the sound exposure of four participants was monitored with noise dose meters. This study compared the exposures experienced at the two festivals, and tested them against the Norwegian guideline and the World Health Organization’s recommendations. Sound levels during the concerts were higher at the festival not regulated by any guideline, and levels there exceeded both the national and the Worlds Health Organization’s recommendations. The results also show that front-of-house measurements reliably predict participant exposure.

  5. Sound Exposure During Outdoor Music Festivals

    Science.gov (United States)

    Tronstad, Tron V.; Gelderblom, Femke B.

    2016-01-01

    Most countries have guidelines to regulate sound exposure at concerts and music festivals. These guidelines limit the allowed sound pressure levels and the concert/festival's duration. In Norway, where there is such a guideline, it is up to the local authorities to impose the regulations. The need to prevent hearing-loss among festival participants is self-explanatory, but knowledge of the actual dose received by visitors is extremely scarce. This study looks at two Norwegian music festivals where only one was regulated by the Norwegian guideline for concert and music festivals. At each festival the sound exposure of four participants was monitored with noise dose meters. This study compared the exposures experienced at the two festivals, and tested them against the Norwegian guideline and the World Health Organization's recommendations. Sound levels during the concerts were higher at the festival not regulated by any guideline, and levels there exceeded both the national and the Worlds Health Organization's recommendations. The results also show that front-of-house measurements reliably predict participant exposure. PMID:27569410

  6. Second sound scattering in superfluid helium

    International Nuclear Information System (INIS)

    Rosgen, T.

    1985-01-01

    Focusing cavities are used to study the scattering of second sound in liquid helium II. The special geometries reduce wall interference effects and allow measurements in very small test volumes. In a first experiment, a double elliptical cavity is used to focus a second sound wave onto a small wire target. A thin film bolometer measures the side scattered wave component. The agreement with a theoretical estimate is reasonable, although some problems arise from the small measurement volume and associated alignment requirements. A second cavity is based on confocal parabolas, thus enabling the use of large planar sensors. A cylindrical heater produces again a focused second sound wave. Three sensors monitor the transmitted wave component as well as the side scatter in two different directions. The side looking sensors have very high sensitivities due to their large size and resistance. Specially developed cryogenic amplifers are used to match them to the signal cables. In one case, a second auxiliary heater is used to set up a strong counterflow in the focal region. The second sound wave then scatters from the induced fluid disturbances

  7. Rationale and design of a randomized trial of home electronic symptom and lung function monitoring to detect cystic fibrosis pulmonary exacerbations: the early intervention in cystic fibrosis exacerbation (eICE) trial.

    Science.gov (United States)

    Lechtzin, N; West, N; Allgood, S; Wilhelm, E; Khan, U; Mayer-Hamblett, N; Aitken, M L; Ramsey, B W; Boyle, M P; Mogayzel, P J; Goss, C H

    2013-11-01

    Acute pulmonary exacerbations are central events in the lives of individuals with cystic fibrosis (CF). Pulmonary exacerbations lead to impaired lung function, worse quality of life, and shorter survival. We hypothesized that aggressive early treatment of acute pulmonary exacerbation may improve clinical outcomes. Describe the rationale of an ongoing trial designed to determine the efficacy of home monitoring of both lung function measurements and symptoms for early detection and subsequent early treatment of acute CF pulmonary exacerbations. A randomized, non-blinded, multi-center trial in 320 individuals with CF aged 14 years and older. The study compares usual care to a twice a week assessment of home spirometry and CF respiratory symptoms using an electronic device with data transmission to the research personnel to identify and trigger early treatment of CF pulmonary exacerbation. Participants will be enrolled in the study for 12 months. The primary endpoint is change in FEV1 (L) from baseline to 12 months determined by a linear mixed effects model incorporating all quarterly FEV1 measurements. Secondary endpoints include time to first acute protocol-defined pulmonary exacerbation, number of acute pulmonary exacerbations, number of hospitalization days for acute pulmonary exacerbation, time from the end of acute pulmonary exacerbation to onset of subsequent pulmonary exacerbation, change in health related quality of life, change in treatment burden, change in CF respiratory symptoms, and adherence to the study protocol. This study is a first step in establishing alternative approaches to the care of CF pulmonary exacerbations. We hypothesize that early treatment of pulmonary exacerbations has the potential to slow lung function decline, reduce respiratory symptoms and improve the quality of life for individuals with CF. © 2013.

  8. Unexpandable lung.

    Science.gov (United States)

    Pereyra, Marco F; Ferreiro, Lucía; Valdés, Luis

    2013-02-01

    Unexpandable lung is a mechanical complication by which the lung does not expand to the chest wall, impeding a normal apposition between the two pleural layers. The main mechanism involved is the restriction of the visceral pleura due to the formation of a fibrous layer along this pleural membrane. This happens because of the presence of an active pleural disease (lung entrapment), which can be resolved if proper therapeutic measures are taken, or a remote disease (trapped lung), in which an irreversible fibrous pleural layer has been formed. The clinical suspicion arises with the presence of post-thoracocentesis hydropneumothorax or a pleural effusion that cannot be drained due to the appearance of thoracic pain. The diagnosis is based on the analysis of the pleural liquid, the determination of pleural pressures as we drain the effusion and on air-contrast chest CT. As both represent the continuity of one same process, the results will depend on the time at which these procedures are done. If, when given a lung that is becoming entrapped, the necessary therapeutic measures are not taken, the final result will be a trapped lung. In this instance, most patients are asymptomatic or have mild exertional dyspnea and therefore they do not require treatment. Nevertheless, in cases of incapacitating dyspnea, it may be necessary to use pleural decortication in order to resolve the symptoms. Copyright © 2012 SEPAR. Published by Elsevier Espana. All rights reserved.

  9. Sounds of a Star

    Science.gov (United States)

    2001-06-01

    colours show element displacements in opposite directions. Geologists monitor how seismic waves generated by earthquakes propagate through the Earth, and thus learn about the inner structure of our planet. The same technique works for stars. The Sun, our nearest star and a typical middle-age member of its class, has been investigated in this way since the 1960's. With "solar seismology" , astronomers have been able to learn much about the inner parts of the star, and not only the outer layers normally visible to the telescopes. In the Sun, heat is bubbling up from the central regions where enormous amount of energy is created by nuclear reactions . In the so-called convective zone , the gas is virtually boiling, and hot gas-bubbles are rising with a speed that is close to that of sound. Much like you can hear when water starts to boil, the turbulent convection in the Sun creates noise . These sound waves then propagate through the solar interior and are reflected on the surface, making it oscillate. This "ringing" is well observed in the Sun, where the amplitude and frequency of the oscillations provide astronomers with plenty of information about the physical conditions in the solar interior. From the Sun to the stars There is every reason to believe that our Sun is a quite normal star of its type. Other stars that are similar to the Sun are therefore likely to pulsate in much the same way as the Sun. The search for such oscillations in other solar-like stars has, however, been a long and difficult one. The problem is simply that the pulsations are tiny, so very great precision is needed in the measurements. However, the last few years have seen considerable progress in asteroseismology, and François Bouchy and Fabien Carrier from the Geneva Observatory have now been able to detect unambiguous acoustic oscillations in the Solar-twin star, Alpha Centauri A. The bright and nearby star Alpha Centauri Alpha Centauri (Alpha Cen) [1] is the brightest star in the constellation

  10. Monitoring of intratidal lung mechanics: a Graphical User Interface for a model-based decision support system for PEEP-titration in mechanical ventilation.

    Science.gov (United States)

    Buehler, S; Lozano-Zahonero, S; Schumann, S; Guttmann, J

    2014-12-01

    In mechanical ventilation, a careful setting of the ventilation parameters in accordance with the current individual state of the lung is crucial to minimize ventilator induced lung injury. Positive end-expiratory pressure (PEEP) has to be set to prevent collapse of the alveoli, however at the same time overdistension should be avoided. Classic approaches of analyzing static respiratory system mechanics fail in particular if lung injury already prevails. A new approach of analyzing dynamic respiratory system mechanics to set PEEP uses the intratidal, volume-dependent compliance which is believed to stay relatively constant during one breath only if neither atelectasis nor overdistension occurs. To test the success of this dynamic approach systematically at bedside or in an animal study, automation of the computing steps is necessary. A decision support system for optimizing PEEP in form of a Graphical User Interface (GUI) was targeted. Respiratory system mechanics were analyzed using the gliding SLICE method. The resulting shapes of the intratidal compliance-volume curve were classified into one of six categories, each associated with a PEEP-suggestion. The GUI should include a graphical representation of the results as well as a quality check to judge the reliability of the suggestion. The implementation of a user-friendly GUI was successfully realized. The agreement between modelled and measured pressure data [expressed as root-mean-square (RMS)] tested during the implementation phase with real respiratory data from two patient studies was below 0.2 mbar for data taken in volume controlled mode and below 0.4 mbar for data taken in pressure controlled mode except for two cases with RMS rational decision-making model for PEEP-titration.

  11. 46 CFR 7.20 - Nantucket Sound, Vineyard Sound, Buzzards Bay, Narragansett Bay, MA, Block Island Sound and...

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 1 2010-10-01 2010-10-01 false Nantucket Sound, Vineyard Sound, Buzzards Bay, Narragansett Bay, MA, Block Island Sound and easterly entrance to Long Island Sound, NY. 7.20 Section 7.20... Atlantic Coast § 7.20 Nantucket Sound, Vineyard Sound, Buzzards Bay, Narragansett Bay, MA, Block Island...

  12. Characteristic sounds facilitate visual search.

    Science.gov (United States)

    Iordanescu, Lucica; Guzman-Martinez, Emmanuel; Grabowecky, Marcia; Suzuki, Satoru

    2008-06-01

    In a natural environment, objects that we look for often make characteristic sounds. A hiding cat may meow, or the keys in the cluttered drawer may jingle when moved. Using a visual search paradigm, we demonstrated that characteristic sounds facilitated visual localization of objects, even when the sounds carried no location information. For example, finding a cat was faster when participants heard a meow sound. In contrast, sounds had no effect when participants searched for names rather than pictures of objects. For example, hearing "meow" did not facilitate localization of the word cat. These results suggest that characteristic sounds cross-modally enhance visual (rather than conceptual) processing of the corresponding objects. Our behavioral demonstration of object-based cross-modal enhancement complements the extensive literature on space-based cross-modal interactions. When looking for your keys next time, you might want to play jingling sounds.

  13. Evaluation of parameters associated with monitoring in vivo of uranium isotopes in the lungs; Avaliacao de parametros associados a monitoracao in vivo de isotopos de uranio nos pulmoes

    Energy Technology Data Exchange (ETDEWEB)

    Juppa, Silvia P.; Lucena, Eder A.; Dantas, Bernardo M.; Dantas, Ana Leticia A., E-mail: adantas@ird.gov.br [Instiluto de Radioprotecao e Dosimetria (IRD/CNEN-RJ), Rio de Janeiro, RJ (Brazil). Laboratorio de Monitoracao In Vivo. Divisao de Dosimetria

    2013-11-01

    The objective of this study is to evaluate the parameters associated with the technique of monitoring individuals exposed to uranium isotopes, aiming to optimize the technique and reduced uncertainties associated.

  14. Incore monitoring device

    International Nuclear Information System (INIS)

    Tai, Ichiro; Shirayama, Shin-pei; Nozaki, Shin-ichi.

    1978-01-01

    Purpose: To provide an incore monitoring device wherein both radiation monitoring and acoustic monitoring are carried out simultaneously by one detector, whereby installation of the device and signal pick-up are facilitated. Incore conditions are accurately grasped. Constitution: When a neutron is irradiated in a state where a DC voltage is applied between the electrode and the vessel in the device, an ionization current is occured by (n.γ) reaction of the transformed substance as in an ionization chamber, Accordingly, a voltage drop occurs at both ends of the resistor of the radiation signal processing system, as a result of which a neutron flux can be detected. Further, when a sound is generated in the reactor, the monitoring device bottom wall which formed by a piezoelectric element detects the sound-waves. This output signal is picked up by the acoustic signal processing system to judge the generation of sound. (Aizawa, K.)

  15. Monitoring of high-density lipoprotein cholesterol level is predictive of EGFR mutation and efficacy of EGFR-TKI in patients with advanced lung adenocarcinoma

    Directory of Open Access Journals (Sweden)

    Lv Y

    2016-01-01

    Full Text Available Yang Lv,1,2 Li-Yun Miao,2 Qiu-Fang Chen,1 Yan Li,2 Zhi-Xiang Shi,1 Xuan-Sheng Ding1 1Department of Clinical Pharmacy, China Pharmaceutical University, Nanjing, Jiangsu, People’s Republic of China; 2Division of Respiratory Medicine, Department of Respiration, The Affiliated Drum Tower Hospital of Nanjing University Medical College, Nanjing University Medical School, Nanjing, Jiangsu, People’s Republic of China Abstract: High-density lipoprotein cholesterol (HDL-C has an inverse association with the incidence of lung cancer. However, whether it can be used as a predictive factor in advanced lung adenocarcinoma patients treated with epidermal growth factor receptor (EGFR tyrosine kinase inhibitors (TKI still remains undefined. This research aimed at studying the relationship of serum HDL-C baseline level and HDL-C kinetics to EGFR mutation, the efficacy of EGFR-TKI, and the predictive value of PFS. The presence of mutation rate in the 192 patients with lung adenocarcinoma was compared within stratified groups. Levels of baseline HDL-C and kinetics of HDL-C were analyzed retrospectively in patients treated with EGFR-TKI harboring EGFR mutation. Univariate and multivariate analyses were performed to investigate the prognostic value of HDL-C. EGFR mutation rate of HDL-C high-level group was significantly higher than that of low-level group (59.0% vs 35.6%, P=0.001. Multivariate logistic analysis showed that high-level HDL-C was an independent predictive factor for EGFR gene mutation (P=0.005; odds ratio =0.417; 95% confidence interval [CI], 0.227–0.768. Patients with a low level of HDL-C before therapy showed a progression of disease in most cases (P<0.001. According to HDL-C kinetics, patients who received EGFR-TKI treatment harboring EGFR mutation were divided into four groups. Univariate analysis showed that patients in nondecreased group had longer progression-free survival (P<0.001; hazard ratio =0.003; 95% CI, 0.001–0.018. Multivariate

  16. Active sound reduction system and method

    NARCIS (Netherlands)

    2016-01-01

    The present invention refers to an active sound reduction system and method for attenuation of sound emitted by a primary sound source, especially for attenuation of snoring sounds emitted by a human being. This system comprises a primary sound source, at least one speaker as a secondary sound

  17. Automatic adventitious respiratory sound analysis: A systematic review.

    Science.gov (United States)

    Pramono, Renard Xaviero Adhi; Bowyer, Stuart; Rodriguez-Villegas, Esther

    2017-01-01

    Automatic detection or classification of adventitious sounds is useful to assist physicians in diagnosing or monitoring diseases such as asthma, Chronic Obstructive Pulmonary Disease (COPD), and pneumonia. While computerised respiratory sound analysis, specifically for the detection or classification of adventitious sounds, has recently been the focus of an increasing number of studies, a standardised approach and comparison has not been well established. To provide a review of existing algorithms for the detection or classification of adventitious respiratory sounds. This systematic review provides a complete summary of methods used in the literature to give a baseline for future works. A systematic review of English articles published between 1938 and 2016, searched using the Scopus (1938-2016) and IEEExplore (1984-2016) databases. Additional articles were further obtained by references listed in the articles found. Search terms included adventitious sound detection, adventitious sound classification, abnormal respiratory sound detection, abnormal respiratory sound classification, wheeze detection, wheeze classification, crackle detection, crackle classification, rhonchi detection, rhonchi classification, stridor detection, stridor classification, pleural rub detection, pleural rub classification, squawk detection, and squawk classification. Only articles were included that focused on adventitious sound detection or classification, based on respiratory sounds, with performance reported and sufficient information provided to be approximately repeated. Investigators extracted data about the adventitious sound type analysed, approach and level of analysis, instrumentation or data source, location of sensor, amount of data obtained, data management, features, methods, and performance achieved. A total of 77 reports from the literature were included in this review. 55 (71.43%) of the studies focused on wheeze, 40 (51.95%) on crackle, 9 (11.69%) on stridor, 9 (11

  18. Understanding Animal Detection of Precursor Earthquake Sounds.

    Science.gov (United States)

    Garstang, Michael; Kelley, Michael C

    2017-08-31

    We use recent research to provide an explanation of how animals might detect earthquakes before they occur. While the intrinsic value of such warnings is immense, we show that the complexity of the process may result in inconsistent responses of animals to the possible precursor signal. Using the results of our research, we describe a logical but complex sequence of geophysical events triggered by precursor earthquake crustal movements that ultimately result in a sound signal detectable by animals. The sound heard by animals occurs only when metal or other surfaces (glass) respond to vibrations produced by electric currents induced by distortions of the earth's electric fields caused by the crustal movements. A combination of existing measurement systems combined with more careful monitoring of animal response could nevertheless be of value, particularly in remote locations.

  19. Magnetospheric radio sounding

    International Nuclear Information System (INIS)

    Ondoh, Tadanori; Nakamura, Yoshikatsu; Koseki, Teruo; Watanabe, Sigeaki; Murakami, Toshimitsu

    1977-01-01

    Radio sounding of the plasmapause from a geostationary satellite has been investigated to observe time variations of the plasmapause structure and effects of the plasma convection. In the equatorial plane, the plasmapause is located, on the average, at 4 R sub(E) (R sub(E); Earth radius), and the plasma density drops outwards from 10 2 -10 3 /cm 3 to 1-10/cm 3 in the plasmapause width of about 600 km. Plasmagrams showing a relation between the virtual range and sounding frequencies are computed by ray tracing of LF-VLF waves transmitted from a geostationary satellite, using model distributions of the electron density in the vicinity of the plasmapause. The general features of the plasmagrams are similar to the topside ionograms. The plasmagram has no penetration frequency such as f 0 F 2 , but the virtual range of the plasmagram increases rapidly with frequency above 100 kHz, since the distance between a satellite and wave reflection point increases rapidly with increasing the electron density inside the plasmapause. The plasmapause sounder on a geostationary satellite has been designed by taking account of an average propagation distance of 2 x 2.6 R sub(E) between a satellite (6.6 R sub(E)) and the plasmapause (4.0 R sub(E)), background noise, range resolution, power consumption, and receiver S/N of 10 dB. The 13-bit Barker coded pulses of baud length of 0.5 msec should be transmitted in direction parallel to the orbital plane at frequencies for 10 kHz-2MHz in a pulse interval of 0.5 sec. The transmitter peak power of 70 watts and 700 watts are required respectively in geomagnetically quiet and disturbed (strong nonthermal continuum emissions) conditions for a 400 meter cylindrical dipole of 1.2 cm diameter on the geostationary satellite. This technique will open new area of radio sounding in the magnetosphere. (auth.)

  20. Lung function

    International Nuclear Information System (INIS)

    Sorichter, S.

    2009-01-01

    The term lung function is often restricted to the assessment of volume time curves measured at the mouth. Spirometry includes the assessment of lung volumes which can be mobilised with the corresponding flow-volume curves. In addition, lung volumes that can not be mobilised, such as the residual volume, or only partially as FRC and TLC can be measured by body plethysmography combined with the determination of the airway resistance. Body plethysmography allows the correct positioning of forced breathing manoeuvres on the volume-axis, e.g. before and after pharmacotherapy. Adding the CO single breath transfer factor (T LCO ), which includes the measurement of the ventilated lung volume using He, enables a clear diagnosis of different obstructive, restrictive or mixed ventilatory defects with and without trapped air. Tests of reversibility and provocation, as well as the assessment of inspiratory mouth pressures (PI max , P 0.1 ) help to classify the underlying disorder and to clarify treatment strategies. For further information and to complete the diagnostic of disturbances of the ventilation, diffusion and/or perfusion (capillar-)arterial bloodgases at rest and under physical strain sometimes amended by ergospirometry are recommended. Ideally, lung function measurements are amended by radiological and nuclear medicine techniques. (orig.) [de

  1. Handbook for sound engineers

    CERN Document Server

    Ballou, Glen

    2015-01-01

    Handbook for Sound Engineers is the most comprehensive reference available for audio engineers, and is a must read for all who work in audio.With contributions from many of the top professionals in the field, including Glen Ballou on interpretation systems, intercoms, assistive listening, and fundamentals and units of measurement, David Miles Huber on MIDI, Bill Whitlock on audio transformers and preamplifiers, Steve Dove on consoles, DAWs, and computers, Pat Brown on fundamentals, gain structures, and test and measurement, Ray Rayburn on virtual systems, digital interfacing, and preamplifiers

  2. Facing Sound - Voicing Art

    DEFF Research Database (Denmark)

    Lønstrup, Ansa

    2013-01-01

    This article is based on examples of contemporary audiovisual art, with a special focus on the Tony Oursler exhibition Face to Face at Aarhus Art Museum ARoS in Denmark in March-July 2012. My investigation involves a combination of qualitative interviews with visitors, observations of the audience´s...... interactions with the exhibition and the artwork in the museum space and short analyses of individual works of art based on reception aesthetics and phenomenology and inspired by newer writings on sound, voice and listening....

  3. JINGLE: THE SOUNDING SYMBOL

    Directory of Open Access Journals (Sweden)

    Bysko Maxim V.

    2013-12-01

    Full Text Available The article considers the role of jingles in the industrial era, from the occurrence of the regular radio broadcasting, sound films and television up of modern video games, audio and video podcasts, online broadcasts, and mobile communications. Jingles are researched from the point of view of the theory of symbols: the forward motion is detected in the process of development of jingles from the social symbols (radio callsigns to the individual signs-images (ringtones. The role of technical progress in the formation of jingles as important cultural audio elements of modern digital civilization.

  4. Do top predators cue on sound production by mesopelagic prey?

    Science.gov (United States)

    Baumann-Pickering, S.; Checkley, D. M., Jr.; Demer, D. A.

    2016-02-01

    Deep-scattering layer (DSL) organisms, comprising a variety of mesopelagic fishes, and squids, siphonophores, crustaceans, and other invertebrates, are preferred prey for numerous large marine predators, e.g. cetaceans, seabirds, and fishes. Some of the DSL species migrate from depth during daylight to feed near the surface at night, transitioning during dusk and dawn. We investigated if any DSL organisms create sound, particularly during the crepuscular periods. Over several nights in summer 2015, underwater sound was recorded in the San Diego Trough using a high-frequency acoustic recording package (HARP, 10 Hz to 100 kHz), suspended from a drifting surface float. Acoustic backscatter from the DSL was monitored nearby using a calibrated multiple-frequency (38, 70, 120, and 200 kHz) split-beam echosounder (Simrad EK60) on a small boat. DSL organisms produced sound, between 300 and 1000 Hz, and the received levels were highest when the animals migrated past the recorder during ascent and descent. The DSL are globally present, so the observed acoustic phenomenon, if also ubiquitous, has wide-reaching implications. Sound travels farther than light or chemicals and thus can be sensed at greater distances by predators, prey, and mates. If sound is a characteristic feature of pelagic ecosystems, it likely plays a role in predator-prey relationships and overall ecosystem dynamics. Our new finding inspires numerous questions such as: Which, how, and why have DSL organisms evolved to create sound, for what do they use it and under what circumstances? Is sound production by DSL organisms truly ubiquitous, or does it depend on the local environment and species composition? How may sound production and perception be adapted to a changing environment? Do predators react to changes in sound? Can sound be used to quantify the composition of mixed-species assemblages, component densities and abundances, and hence be used in stock assessment or predictive modeling?

  5. Leakage monitoring device and method

    International Nuclear Information System (INIS)

    Yamada, Izumi; Matsui, Yuji; Fujimori, Haruo.

    1995-01-01

    In a water leakage monitor for a steam generator, output signals from an acoustic sensor disposed in the vicinity of a region to be monitored is subjected to phasing calculation (beam forming calculation) to determine the distribution of a sound source intensity distribution. A peak is retrieved based on the distribution of the sound source intensity distribution. A correction coefficient depending on the position of the peak is multiplied to the sound source intensity. The presence or absence of leakage is determined based on the degree of the sound source intensity after the completion of correction. Namely, a relative value of sound source intensity for each of the portions in the region to be monitored is determined, and the point of the greatest sound source intensity is assumed as a leaking point, to determine the position of the leakage. An absolute value of the sound source intensity at the leaking point is determined by such a constitution that a correction coefficient depending on the position is multiplied to the intensity of the position of the peak in the distribution of the sound intensity. A threshold value for the determination of the presence or absence of the leakage can be set if a relation between an amount of the leakage previously determined experimentally and the intensity of the sound source. Then, a countermeasure can easily be taken after the detection of the leakage and a restoring operation can be carried out rapidly after the occurrence of leakage while avoiding unnecessary shutdown. (N.H.)

  6. Open lung biopsy

    Science.gov (United States)

    Biopsy - open lung ... An open lung biopsy is done in the hospital using general anesthesia . This means you will be asleep and ... The open lung biopsy is done to evaluate lung problems seen on x-ray or CT scan .

  7. Lung Cancer: Glossary

    Science.gov (United States)

    ... professional support team today. Learn More . Find more lung cancer resources. Learn More Donate Today! What is Lung ... to Give How Your Support Helps Events Lung Cancer Awareness © Lung Cancer Alliance. The information presented in this website ...

  8. Lung Cancer Prevention

    Science.gov (United States)

    ... Colorectal Cancer Kidney (Renal Cell) Cancer Leukemia Liver Cancer Lung Cancer Lymphoma Pancreatic Cancer Prostate Cancer Skin Cancer ... following PDQ summaries for more information about lung cancer: Lung Cancer Screening Non-Small Cell Lung Cancer Treatment ...

  9. Lung cancer - small cell

    Science.gov (United States)

    Cancer - lung - small cell; Small cell lung cancer; SCLC ... About 15% of all lung cancer cases are SCLC. Small cell lung cancer is slightly more common in men than women. Almost all cases of SCLC are ...

  10. [Lung scintigraphy].

    Science.gov (United States)

    Schümichen, Carl; Schmidt, Matthias; Krause, Thomas

    2018-06-01

    The S1 guideline for lung scintigraphy has been updated and extended in order to emphasize the advantages oft the method in detecting acute pulmonary embolism (PE) in the periphery oft the lung (subsegmental PE), in underlying subacute and chronic pulmonary disorders, as well as in detecting chronic LE (CTEPH). Method of choice is ventilation / perfusion (V/P) SPECT or V/P SPECT/CT with even higher specificity. Because of its high sensitivity, a threshold (V/P mismatch in at least one segment or two subsegments) is introduced to avoid overtreatment. In case of a change in the therapeutic approach (observation only instead of anticoaculation) the threshold can be omitted. New data concerning the clinical and therapeutical impact of subsegmental PE are included, the chapters open questions have been extented. Other indications for V/P SPECT (secondary diagnoses, abnormalities in pulmonary perfusion, prediction of postoperative lung function) are presented with new data. Schattauer GmbH.

  11. Lung radiopharmaceuticals

    International Nuclear Information System (INIS)

    Gonzalez, B.M.

    1994-01-01

    Indication or main clinical use of Lung radiopharmaceuticals is presented and clasification of radiopharmaceuticals as ventilation and perfusion studies. Perfusion radiopharmaceuticals, main controls for administration quality acceptance. Clearence after blood administration and main clinical applications. Ventilation radiopharmaceuticals, gases and aerosols, characteristics of a ideal radioaerosol, techniques of good inhalation procedure, clinical applications. Comparison of several radiopharmaceuticals reflering to retention time as 50% administered dose, percent administered dose at 6 hours post inhalation, blood activity at 30 and 60 minutes post inhalation, initial lung absorbed dose, cumulated activity.Kinetic description of two radiopharmaceuticals, 99mTcDTPA and 99mTc-PYP

  12. Sound Velocity in Soap Foams

    International Nuclear Information System (INIS)

    Wu Gong-Tao; Lü Yong-Jun; Liu Peng-Fei; Li Yi-Ning; Shi Qing-Fan

    2012-01-01

    The velocity of sound in soap foams at high gas volume fractions is experimentally studied by using the time difference method. It is found that the sound velocities increase with increasing bubble diameter, and asymptotically approach to the value in air when the diameter is larger than 12.5 mm. We propose a simple theoretical model for the sound propagation in a disordered foam. In this model, the attenuation of a sound wave due to the scattering of the bubble wall is equivalently described as the effect of an additional length. This simplicity reasonably reproduces the sound velocity in foams and the predicted results are in good agreement with the experiments. Further measurements indicate that the increase of frequency markedly slows down the sound velocity, whereas the latter does not display a strong dependence on the solution concentration

  13. Gefinex 400S (Sampo) EM-Soundings at Olkiluoto 2007

    International Nuclear Information System (INIS)

    Jokinen, T.; Lehtimaeki, J.

    2007-09-01

    In the beginning of June 2007 Geological Survey of Finland carried out electromagnetic frequency soundings with Gefinex 400S equipment (Sampo) at Onkalo situated in Olkiluoto nuclear power plant area. The same soundings sites were the first time measured and marked in 2004 and repeated after it yearly. The aim of the measurements is to monitor the changes of groundwater conditions by the changes of the electric conductivity of the earth at ONKALO and repository area. The measurements form two 1400 m long broadside profiles, which have 200 m mutual distance and 200 m station separation. The profiles have been measured using 200, 500, and 800 m coil separations. The total number of the soundings stations is 48. In 2007 at 8 sounding stations the transmitter and/or receiver sites were changed and the line L11.400 was substituted by line L11.500. Some changes helped but anyway there were 6 stations that could not be measured because of the strong electromagnetic noise. The numerous power lines and the cables of the area generate local 3-D effects on the sounding curves, but the repeatability of the results is good. However, most suitable for monitoring purposes are the sites without strong 3-D effects. Comparison of results 2004-2007 shows small differences at some sounding sites. (orig.)

  14. Analysis of environmental sounds

    Science.gov (United States)

    Lee, Keansub

    Environmental sound archives - casual recordings of people's daily life - are easily collected by MPS players or camcorders with low cost and high reliability, and shared in the web-sites. There are two kinds of user generated recordings we would like to be able to handle in this thesis: Continuous long-duration personal audio and Soundtracks of short consumer video clips. These environmental recordings contain a lot of useful information (semantic concepts) related with activity, location, occasion and content. As a consequence, the environment archives present many new opportunities for the automatic extraction of information that can be used in intelligent browsing systems. This thesis proposes systems for detecting these interesting concepts on a collection of these real-world recordings. The first system is to segment and label personal audio archives - continuous recordings of an individual's everyday experiences - into 'episodes' (relatively consistent acoustic situations lasting a few minutes or more) using the Bayesian Information Criterion and spectral clustering. The second system is for identifying regions of speech or music in the kinds of energetic and highly-variable noise present in this real-world sound. Motivated by psychoacoustic evidence that pitch is crucial in the perception and organization of sound, we develop a noise-robust pitch detection algorithm to locate speech or music-like regions. To avoid false alarms resulting from background noise with strong periodic components (such as air-conditioning), a new scheme is added in order to suppress these noises in the domain of autocorrelogram. In addition, the third system is to automatically detect a large set of interesting semantic concepts; which we chose for being both informative and useful to users, as well as being technically feasible. These 25 concepts are associated with people's activities, locations, occasions, objects, scenes and sounds, and are based on a large collection of

  15. Sounds like Team Spirit

    Science.gov (United States)

    Hoffman, Edward

    2002-01-01

    I recently accompanied my son Dan to one of his guitar lessons. As I sat in a separate room, I focused on the music he was playing and the beautiful, robust sound that comes from a well-played guitar. Later that night, I woke up around 3 am. I tend to have my best thoughts at this hour. The trouble is I usually roll over and fall back asleep. This time I was still awake an hour later, so I got up and jotted some notes down in my study. I was thinking about the pure, honest sound of a well-played instrument. From there my mind wandered into the realm of high-performance teams and successful projects. (I know this sounds weird, but this is the sort of thing I think about at 3 am. Maybe you have your own weird thoughts around that time.) Consider a team in relation to music. It seems to me that a crack team can achieve a beautiful, perfect unity in the same way that a band of brilliant musicians can when they're in harmony with one another. With more than a little satisfaction I have to admit, I started to think about the great work performed for you by the Knowledge Sharing team, including this magazine you are reading. Over the past two years I personally have received some of my greatest pleasures as the APPL Director from the Knowledge Sharing activities - the Masters Forums, NASA Center visits, ASK Magazine. The Knowledge Sharing team expresses such passion for their work, just like great musicians convey their passion in the music they play. In the case of Knowledge Sharing, there are many factors that have made this so enjoyable (and hopefully worthwhile for NASA). Three ingredients come to mind -- ingredients that have produced a signature sound. First, through the crazy, passionate playing of Alex Laufer, Michelle Collins, Denise Lee, and Todd Post, I always know that something startling and original is going to come out of their activities. This team has consistently done things that are unique and innovative. For me, best of all is that they are always

  16. Sound therapies for tinnitus management.

    Science.gov (United States)

    Jastreboff, Margaret M

    2007-01-01

    Many people with bothersome (suffering) tinnitus notice that their tinnitus changes in different acoustical surroundings, it is more intrusive in silence and less profound in the sound enriched environments. This observation led to the development of treatment methods for tinnitus utilizing sound. Many of these methods are still under investigation in respect to their specific protocol and effectiveness and only some have been objectively evaluated in clinical trials. This chapter will review therapies for tinnitus using sound stimulation.

  17. Automatic Bowel Motility Evaluation Technique for Noncontact Sound Recordings

    Directory of Open Access Journals (Sweden)

    Ryunosuke Sato

    2018-06-01

    Full Text Available Information on bowel motility can be obtained via magnetic resonance imaging (MRIs and X-ray imaging. However, these approaches require expensive medical instruments and are unsuitable for frequent monitoring. Bowel sounds (BS can be conveniently obtained using electronic stethoscopes and have recently been employed for the evaluation of bowel motility. More recently, our group proposed a novel method to evaluate bowel motility on the basis of BS acquired using a noncontact microphone. However, the method required manually detecting BS in the sound recordings, and manual segmentation is inconvenient and time consuming. To address this issue, herein, we propose a new method to automatically evaluate bowel motility for noncontact sound recordings. Using simulations for the sound recordings obtained from 20 human participants, we showed that the proposed method achieves an accuracy of approximately 90% in automatic bowel sound detection when acoustic feature power-normalized cepstral coefficients are used as inputs to artificial neural networks. Furthermore, we showed that bowel motility can be evaluated based on the three acoustic features in the time domain extracted by our method: BS per minute, signal-to-noise ratio, and sound-to-sound interval. The proposed method has the potential to contribute towards the development of noncontact evaluation methods for bowel motility.

  18. Sound [signal] noise

    DEFF Research Database (Denmark)

    Bjørnsten, Thomas

    2012-01-01

    The article discusses the intricate relationship between sound and signification through notions of noise. The emergence of new fields of sonic artistic practices has generated several questions of how to approach sound as aesthetic form and material. During the past decade an increased attention...... has been paid to, for instance, a category such as ‘sound art’ together with an equally strengthened interest in phenomena and concepts that fall outside the accepted aesthetic procedures and constructions of what we traditionally would term as musical sound – a recurring example being ‘noise’....

  19. Musical Sound, Instruments, and Equipment

    Science.gov (United States)

    Photinos, Panos

    2017-12-01

    'Musical Sound, Instruments, and Equipment' offers a basic understanding of sound, musical instruments and music equipment, geared towards a general audience and non-science majors. The book begins with an introduction of the fundamental properties of sound waves, and the perception of the characteristics of sound. The relation between intensity and loudness, and the relation between frequency and pitch are discussed. The basics of propagation of sound waves, and the interaction of sound waves with objects and structures of various sizes are introduced. Standing waves, harmonics and resonance are explained in simple terms, using graphics that provide a visual understanding. The development is focused on musical instruments and acoustics. The construction of musical scales and the frequency relations are reviewed and applied in the description of musical instruments. The frequency spectrum of selected instruments is explored using freely available sound analysis software. Sound amplification and sound recording, including analog and digital approaches, are discussed in two separate chapters. The book concludes with a chapter on acoustics, the physical factors that affect the quality of the music experience, and practical ways to improve the acoustics at home or small recording studios. A brief technical section is provided at the end of each chapter, where the interested reader can find the relevant physics and sample calculations. These quantitative sections can be skipped without affecting the comprehension of the basic material. Questions are provided to test the reader's understanding of the material. Answers are given in the appendix.

  20. Sounding out the logo shot

    OpenAIRE

    Nicolai Jørgensgaard Graakjær

    2013-01-01

    This article focuses on how sound in combination with visuals (i.e. ‘branding by’) may possibly affect the signifying potentials (i.e. ‘branding effect’) of products and corporate brands (i.e. ‘branding of’) during logo shots in television commercials (i.e. ‘branding through’). This particular focus adds both to the understanding of sound in television commercials and to the understanding of sound brands. The article firstly presents a typology of sounds. Secondly, this typology is applied...

  1. Frequency shifting approach towards textual transcription of heartbeat sounds.

    Science.gov (United States)

    Arvin, Farshad; Doraisamy, Shyamala; Safar Khorasani, Ehsan

    2011-10-04

    Auscultation is an approach for diagnosing many cardiovascular problems. Automatic analysis of heartbeat sounds and extraction of its audio features can assist physicians towards diagnosing diseases. Textual transcription allows recording a continuous heart sound stream using a text format which can be stored in very small memory in comparison with other audio formats. In addition, a text-based data allows applying indexing and searching techniques to access to the critical events. Hence, the transcribed heartbeat sounds provides useful information to monitor the behavior of a patient for the long duration of time. This paper proposes a frequency shifting method in order to improve the performance of the transcription. The main objective of this study is to transfer the heartbeat sounds to the music domain. The proposed technique is tested with 100 samples which were recorded from different heart diseases categories. The observed results show that, the proposed shifting method significantly improves the performance of the transcription.

  2. Frequency shifting approach towards textual transcription of heartbeat sounds

    Directory of Open Access Journals (Sweden)

    Safar Khorasani Ehsan

    2011-10-01

    Full Text Available Abstract Auscultation is an approach for diagnosing many cardiovascular problems. Automatic analysis of heartbeat sounds and extraction of its audio features can assist physicians towards diagnosing diseases. Textual transcription allows recording a continuous heart sound stream using a text format which can be stored in very small memory in comparison with other audio formats. In addition, a text-based data allows applying indexing and searching techniques to access to the critical events. Hence, the transcribed heartbeat sounds provides useful information to monitor the behavior of a patient for the long duration of time. This paper proposes a frequency shifting method in order to improve the performance of the transcription. The main objective of this study is to transfer the heartbeat sounds to the music domain. The proposed technique is tested with 100 samples which were recorded from different heart diseases categories. The observed results show that, the proposed shifting method significantly improves the performance of the transcription.

  3. Lung Transplant

    Science.gov (United States)

    ... Severity of the recipient's lung disease Recipient's overall health Likelihood that the transplant will be successful Immediately before ... will begin within days of your surgery. Your health care team will likely work with you to design an exercise program that's right for you. Your doctor may ...

  4. Lung cancer

    DEFF Research Database (Denmark)

    Hansen, H H; Rørth, M

    1999-01-01

    The results of the many clinical trials published in 1997 had only modest impact on the treatment results using either cytostatic agents alone or combined with radiotherapy in lung cancer. In SCLC, combination chemotherapy including platin-compounds (cisplatin, carboplatin) and the podophyllotoxins...

  5. Sounding the Alarm: An Introduction to Ecological Sound Art

    Directory of Open Access Journals (Sweden)

    Jonathan Gilmurray

    2016-12-01

    Full Text Available In recent years, a number of sound artists have begun engaging with ecological issues through their work, forming a growing movement of ˝ecological sound art˝. This paper traces its development, examines its influences, and provides examples of the artists whose work is currently defining this important and timely new field.

  6. A single-arm, multicenter, safety-monitoring, phase IV study of icotinib in treating advanced non-small cell lung cancer (NSCLC).

    Science.gov (United States)

    Hu, Xingsheng; Han, Baohui; Gu, Aiqin; Zhang, Yiping; Jiao, Shun Chang; Wang, Chang-Li; He, Jintao; Jia, Xueke; Zhang, Li; Peng, Jiewen; Wu, Meina; Ying, Kejing; Wang, Junye; Ma, Kewei; Zhang, Shucai; You, Changxuan; Tan, Fenlai; Wang, Yinxiang; Ding, Lieming; Sun, Yan

    2014-11-01

    The phase 3 ICOGEN trial established the non-inferiority of icotinib to gefitinib in terms of progression-free survival (PFS) in non-small cell lung cancer (NSCLC) patients, and this led to the approval of icotinib for NSCLC by the China Food and Drug Administration. A phase 4 study was conducted to assess the safety and efficacy of icotinib in a broad range of patients with advanced NSCLC across China. This study retrospectively analyzed data from unresectable, recurrent, and/or advanced NSCLC patients who received oral icotinib 125 mg three times per day. The primary endpoint was safety. The secondary endpoints included objective response rate (ORR) and disease control rate (DCR), which were investigated overall and in subgroups such as patients with an EGFR mutation and elderly patients. Between August, 2011 and August, 2012, a total of 6087 advanced NSCLC patients were registered in this study, of which 5549 were evaluable for safety and tumor response. The median age was 63 years (range 21-95 years), and 1571 (28.3%) patients were over the age of 70. The majority of patients were non-smokers, and had adenocarcinoma and stage IV disease. The overall incidence of adverse drug reactions (ADRs) of any grade was 31.5%. The most common ADRs included rash (17.4%) and diarrhea (8.5%), and three patients experienced interstitial lung disease (ILD). The ORR and DCR were 30.0% and 80.6%, respectively, for the overall population, and 33.4% and 81.2%, 30.3% and 80.3%, and 30.4% and 89.3%, for first-line, second-line, and third-line or multiple line subsets, respectively. In 665 EGFR-mutated patients who were evaluable for tumor response, the ORR and DCR were 49.2% (327/665) and 92.3% (614/665), respectively. The data from over 6000 patients was consistent with the results of the ICOGEN study. Icotinib demonstrated a favorable toxicity profile and efficacy in the routine clinical setting. Copyright © 2014 Elsevier Ireland Ltd. All rights reserved.

  7. Cone-beam computed tomography for lung cancer – validation with CT and monitoring tumour response during chemo-radiation therapy

    International Nuclear Information System (INIS)

    Michienzi, Alissa; Kron, Tomas; Callahan, Jason; Plumridge, Nikki; Ball, David; Everitt, Sarah

    2017-01-01

    Cone-beam computed tomography (CBCT) is a valuable image-guidance tool in radiation therapy (RT). This study was initiated to assess the accuracy of CBCT for quantifying non-small cell lung cancer (NSCLC) tumour volumes compared to the anatomical ‘gold standard’, CT. Tumour regression or progression on CBCT was also analysed. Patients with Stage I-III NSCLC, prescribed 60 Gy in 30 fractions RT with concurrent platinum-based chemotherapy, routine CBCT and enrolled in a prospective study of serial PET/CT (baseline, weeks two and four) were eligible. Time-matched CBCT and CT gross tumour volumes (GTVs) were manually delineated by a single observer on MIM software, and were analysed descriptively and using Pearson's correlation coefficient (r) and linear regression (R 2 ). Of 94 CT/CBCT pairs, 30 patients were eligible for inclusion. The mean (± SD) CT GTV vs CBCT GTV on the four time-matched pairs were 95 (±182) vs 98.8 (±160.3), 73.6 (±132.4) vs 70.7 (±96.6), 54.7 (±92.9) vs 61.0 (±98.8) and 61.3 (±53.3) vs 62.1 (±47.9) respectively. Pearson's correlation coefficient (r) was 0.98 (95% CI 0.97–0.99, ρ < 0.001). The mean (±SD) CT/CBCT Dice's similarity coefficient was 0.66 (±0.16). Of 289 CBCT scans, tumours in 27 (90%) patients regressed by a mean (±SD) rate of 1.5% (±0.75) per fraction. The mean (±SD) GTV regression was 43.1% (±23.1) from the first to final CBCT. Primary lung tumour volumes observed on CBCT and time-matched CT are highly correlated (although not identical), thereby validating observations of GTV regression on CBCT in NSCLC.

  8. Development of Prediction Tool for Sound Absorption and Sound Insulation for Sound Proof Properties

    OpenAIRE

    Yoshio Kurosawa; Takao Yamaguchi

    2015-01-01

    High frequency automotive interior noise above 500 Hz considerably affects automotive passenger comfort. To reduce this noise, sound insulation material is often laminated on body panels or interior trim panels. For a more effective noise reduction, the sound reduction properties of this laminated structure need to be estimated. We have developed a new calculate tool that can roughly calculate the sound absorption and insulation properties of laminate structure and handy ...

  9. Sound, memory and interruption

    DEFF Research Database (Denmark)

    Pinder, David

    2016-01-01

    This chapter considers how art can interrupt the times and spaces of urban development so they might be imagined, experienced and understood differently. It focuses on the construction of the M11 Link Road through north-east London during the 1990s that demolished hundreds of homes and displaced...... around a thousand people. The highway was strongly resisted and it became the site of one of the country’s longest and largest anti-road struggles. The chapter addresses specifically Graeme Miller’s sound walk LINKED (2003), which for more than a decade has been broadcasting memories and stories...... of people who were violently displaced by the road as well as those who actively sought to halt it. Attention is given to the walk’s interruption of senses of the given and inevitable in two main ways. The first is in relation to the pace of the work and its deployment of slowness and arrest in a context...

  10. Recycling Sounds in Commercials

    DEFF Research Database (Denmark)

    Larsen, Charlotte Rørdam

    2012-01-01

    Commercials offer the opportunity for intergenerational memory and impinge on cultural memory. TV commercials for foodstuffs often make reference to past times as a way of authenticating products. This is frequently achieved using visual cues, but in this paper I would like to demonstrate how...... such references to the past and ‘the good old days’ can be achieved through sounds. In particular, I will look at commercials for Danish non-dairy spreads, especially for OMA margarine. These commercials are notable in that they contain a melody and a slogan – ‘Say the name: OMA margarine’ – that have basically...... remained the same for 70 years. Together these identifiers make OMA an interesting Danish case to study. With reference to Ann Rigney’s memorial practices or mechanisms, the study aims to demonstrate how the auditory aspects of Danish margarine commercials for frying tend to be limited in variety...

  11. The sounds of science

    Science.gov (United States)

    Carlowicz, Michael

    As scientists carefully study some aspects of the ocean environment, are they unintentionally distressing others? That is a question to be answered by Robert Benson and his colleagues in the Center for Bioacoustics at Texas A&M University.With help from a 3-year, $316,000 grant from the U.S. Office of Naval Research, Benson will study how underwater noise produced by naval operations and other sources may affect marine mammals. In Benson's study, researchers will generate random sequences of low-frequency, high-intensity (180-decibel) sounds in the Gulf of Mexico, working at an approximate distance of 1 km from sperm whale herds. Using an array of hydrophones, the scientists will listen to the characteristic clicks and whistles of the sperm whales to detect changes in the animals' direction, speed, and depth, as derived from fluctuations in their calls.

  12. Sound of proteins

    DEFF Research Database (Denmark)

    2007-01-01

    In my group we work with Molecular Dynamics to model several different proteins and protein systems. We submit our modelled molecules to changes in temperature, changes in solvent composition and even external pulling forces. To analyze our simulation results we have so far used visual inspection...... and statistical analysis of the resulting molecular trajectories (as everybody else!). However, recently I started assigning a particular sound frequency to each amino acid in the protein, and by setting the amplitude of each frequency according to the movement amplitude we can "hear" whenever two aminoacids...... example of soundfile was obtained from using Steered Molecular Dynamics for stretching the neck region of the scallop myosin molecule (in rigor, PDB-id: 1SR6), in such a way as to cause a rotation of the myosin head. Myosin is the molecule responsible for producing the force during muscle contraction...

  13. SU-G-JeP4-12: Real-Time Organ Motion Monitoring Using Ultrasound and KV Fluoroscopy During Lung SBRT Delivery

    International Nuclear Information System (INIS)

    Omari, E; Tai, A; Li, X; Cooper, D; Lachaine, M

    2016-01-01

    Purpose: Real-time ultrasound monitoring during SBRT is advantageous in understanding and identifying motion irregularities which may cause geometric misses. In this work, we propose to utilize real-time ultrasound to track the diaphragm in conjunction with periodical kV fluoroscopy to monitor motion of tumor or landmarks during SBRT delivery. Methods: Transabdominal Ultrasound (TAUS) b-mode images were collected from 10 healthy volunteers using the Clarity Autoscan System (Elekta). The autoscan transducer, which has a center frequency of 5 MHz, was utilized for the scans. The acquired images were contoured using the Clarity Automatic Fusion and Contouring workstation software. Monitoring sessions of 5 minute length were observed and recorded. The position correlation between tumor and diaphragm could be established with periodic kV fluoroscopy periodically acquired during treatment with Elekta XVI. We acquired data using a tissue mimicking ultrasound phantom with embedded spheres placed on a motion stand using ultrasound and kV Fluoroscopy. MIM software was utilized for image fusion. Correlation of diaphragm and target motion was also validated using 4D-MRI and 4D-CBCT. Results: The diaphragm was visualized as a hyperechoic region on the TAUS b-mode images. Volunteer set-up can be adjusted such that TAUS probe will not interfere with treatment beams. A segment of the diaphragm was contoured and selected as our tracking structure. Successful monitoring sessions of the diaphragm were recorded. For some volunteers, diaphragm motion over 2 times larger than the initial motion has been observed during tracking. For the phantom study, we were able to register the 2D kV Fluoroscopy with the US images for position comparison. Conclusion: We demonstrated the feasibility of tracking the diaphragm using real-time ultrasound. Real-time tracking can help in identifying such irregularities in the respiratory motion which is correlated to tumor motion. We also showed the

  14. Designing a Sound Reducing Wall

    Science.gov (United States)

    Erk, Kendra; Lumkes, John; Shambach, Jill; Braile, Larry; Brickler, Anne; Matthys, Anna

    2015-01-01

    Acoustical engineers use their knowledge of sound to design quiet environments (e.g., classrooms and libraries) as well as to design environments that are supposed to be loud (e.g., concert halls and football stadiums). They also design sound barriers, such as the walls along busy roadways that decrease the traffic noise heard by people in…

  15. Thinking The City Through Sound

    DEFF Research Database (Denmark)

    Kreutzfeldt, Jacob

    2011-01-01

    n Acoutic Territories. Sound Culture and Everyday Life Brandon LaBelle sets out to charts an urban topology through sound. Working his way through six acoustic territories: underground, home, sidewalk, street, shopping mall and sky/radio LaBelle investigates tensions and potentials inherent in mo...

  16. The Textile Form of Sound

    DEFF Research Database (Denmark)

    Bendixen, Cecilie

    2010-01-01

    The aim of this article is to shed light on a small part of the research taking place in the textile field. The article describes an ongoing PhD research project on textiles and sound and outlines the project's two main questions: how sound can be shaped by textiles and conversely how textiles can...

  17. Basic semantics of product sounds

    NARCIS (Netherlands)

    Özcan Vieira, E.; Van Egmond, R.

    2012-01-01

    Product experience is a result of sensory and semantic experiences with product properties. In this paper, we focus on the semantic attributes of product sounds and explore the basic components for product sound related semantics using a semantic differential paradigmand factor analysis. With two

  18. Measuring the 'complexity' of sound

    Indian Academy of Sciences (India)

    cate that specialized regions of the brain analyse different types of sounds [1]. Music, ... The left panel of figure 1 shows examples of sound–pressure waveforms from the nat- ... which is shown in the right panels in the spectrographic representation using a 45 Hz .... Plot of SFM(t) vs. time for different environmental sounds.

  19. The Aesthetic Experience of Sound

    DEFF Research Database (Denmark)

    Breinbjerg, Morten

    2005-01-01

    to react on. In an ecological understanding of hearing our detection of audible information affords us ways of responding to our environment. In my paper I will address both these ways of using sound in relation to computer games. Since a game player is responsible for the unfolding of the game, his......The use of sound in (3D) computer games basically falls in two. Sound is used as an element in the design of the set and as a narrative. As set design sound stages the nature of the environment, it brings it to life. As a narrative it brings us information that we can choose to or perhaps need...... exploration of the virtual space laid out before him is pertinent. In this mood of exploration sound is important and heavily contributing to the aesthetic of the experience....

  20. Controlling sound with acoustic metamaterials

    DEFF Research Database (Denmark)

    Cummer, Steven A. ; Christensen, Johan; Alù, Andrea

    2016-01-01

    Acoustic metamaterials can manipulate and control sound waves in ways that are not possible in conventional materials. Metamaterials with zero, or even negative, refractive index for sound offer new possibilities for acoustic imaging and for the control of sound at subwavelength scales....... The combination of transformation acoustics theory and highly anisotropic acoustic metamaterials enables precise control over the deformation of sound fields, which can be used, for example, to hide or cloak objects from incident acoustic energy. Active acoustic metamaterials use external control to create......-scale metamaterial structures and converting laboratory experiments into useful devices. In this Review, we outline the designs and properties of materials with unusual acoustic parameters (for example, negative refractive index), discuss examples of extreme manipulation of sound and, finally, provide an overview...

  1. Player Collaboration in the Explorative Sound Environment ToneInk

    DEFF Research Database (Denmark)

    Hansen, Anne-Marie S.; Andersen, Hans Jørgen; Raudaskoski, Pirkko Liisa

    2016-01-01

    mutual awareness, and in general were more passive when they needed to monitor a screen interface that supported the sound environment. Player collaboration was strongest when players negotiated rhythm, while the negotiation of melody was temporally offset and consisted of long individual explorations....

  2. The Influence of Neonatal Intensive Care Unit Design on Sound Level

    Directory of Open Access Journals (Sweden)

    Hsin-Li Chen

    2009-12-01

    Conclusion: The sound level measured in the enclosed space was quieter than in the open space. The design of bed space should be taken into consideration when building a new NICU. Besides the design of NICU architecture, continuous monitoring of sound level in the NICU is important to maintain a quiet environment.

  3. Compliance with PET acquisition protocols for therapeutic monitoring of erlotinib therapy in an international trial for patients with non-small cell lung cancer

    International Nuclear Information System (INIS)

    Binns, David S.; Callahan, Jason; Mileshkin, Linda; Pirzkall, Andrea; Yu, Wei; Fine, Bernard M.; Conti, Peter; Scott, Andrew M.; Macfarlane, David; Hicks, Rodney J.

    2011-01-01

    The Response Evaluation Criteria in Solid Tumors (RECIST) are widely used but have recognized limitations. Molecular imaging assessments, including changes in 18 F-deoxyglucose (FDG) or 18 F-deoxythymidine (FLT) uptake by positron emission tomography (PET), may provide earlier, more robust evaluation of treatment efficacy. A prospective trial evaluated on-treatment changes in FDG and FLT PET imaging among patients with relapsed or recurrent non-small cell lung cancer treated with erlotinib to assess the relationship between PET-evaluated response and clinical outcomes. We describe an audit of compliance with the study imaging charter, to establish the feasibility of achieving methodological consistency in a multicentre setting. Patients underwent PET scans at baseline and approximately day 14 and day 56 of treatment (n = 73, 66 and 51 studies, and n = 73, 63 and 50 studies for FDG PET and FLT PET, respectively). Blood glucose levels were within the target range for all FDG PET scans. Charter-specified uptake times were achieved in 86% (63/73) and 89% (65/73) of baseline FDG and FLT scans, respectively. On-treatment scans were less consistent: 72% (84/117) and 68% (77/113), respectively, achieved the target of ±5 min of baseline uptake time. However, 96% (112/117) and 94% (106/113) of FDG and FLT PET studies, respectively, were within ±15 min. Bland-Altman analysis of intra-individual hepatic average standardized uptake value (SUV ave ), to assess reproducibility, showed only a small difference in physiological uptake (-0.006 ± 0.224 in 118 follow-up FDG scans and 0.09 ± 0.81 in 111 follow-up FLT scans). It is possible to achieve high reproducibility of scan acquisition methodology, provided that strict imaging compliance guidelines are mandated in the study protocol. (orig.)

  4. Compliance with PET acquisition protocols for therapeutic monitoring of erlotinib therapy in an international trial for patients with non-small cell lung cancer

    Energy Technology Data Exchange (ETDEWEB)

    Binns, David S.; Callahan, Jason; Mileshkin, Linda [The Peter MacCallum Cancer Centre, Melbourne (Australia); Pirzkall, Andrea; Yu, Wei; Fine, Bernard M. [Genentech, Inc., South San Francisco, CA (United States); Conti, Peter [University of Southern California Kenneth Norris Medical Center, Los Angeles, CA (United States); Scott, Andrew M. [The University of Melbourne and The Austin Hospital, Centre for PET, and Ludwig Institute for Cancer Research, Victoria (Australia); Macfarlane, David [Queensland PET Service, Royal Brisbane and Women' s Hospital, Brisbane (Australia); Hicks, Rodney J. [The University of Melbourne and The Peter MacCallum Cancer Centre, Departments of Medicine and Radiology, East Melbourne, VIC (Australia); The Peter MacCallum Cancer Centre, Melbourne (Australia)

    2011-04-15

    The Response Evaluation Criteria in Solid Tumors (RECIST) are widely used but have recognized limitations. Molecular imaging assessments, including changes in {sup 18}F-deoxyglucose (FDG) or {sup 18}F-deoxythymidine (FLT) uptake by positron emission tomography (PET), may provide earlier, more robust evaluation of treatment efficacy. A prospective trial evaluated on-treatment changes in FDG and FLT PET imaging among patients with relapsed or recurrent non-small cell lung cancer treated with erlotinib to assess the relationship between PET-evaluated response and clinical outcomes. We describe an audit of compliance with the study imaging charter, to establish the feasibility of achieving methodological consistency in a multicentre setting. Patients underwent PET scans at baseline and approximately day 14 and day 56 of treatment (n = 73, 66 and 51 studies, and n = 73, 63 and 50 studies for FDG PET and FLT PET, respectively). Blood glucose levels were within the target range for all FDG PET scans. Charter-specified uptake times were achieved in 86% (63/73) and 89% (65/73) of baseline FDG and FLT scans, respectively. On-treatment scans were less consistent: 72% (84/117) and 68% (77/113), respectively, achieved the target of {+-}5 min of baseline uptake time. However, 96% (112/117) and 94% (106/113) of FDG and FLT PET studies, respectively, were within {+-}15 min. Bland-Altman analysis of intra-individual hepatic average standardized uptake value (SUV{sub ave}), to assess reproducibility, showed only a small difference in physiological uptake (-0.006 {+-} 0.224 in 118 follow-up FDG scans and 0.09 {+-} 0.81 in 111 follow-up FLT scans). It is possible to achieve high reproducibility of scan acquisition methodology, provided that strict imaging compliance guidelines are mandated in the study protocol. (orig.)

  5. Seismic and Biological Sources of Ambient Ocean Sound

    Science.gov (United States)

    Freeman, Simon Eric

    Sound is the most efficient radiation in the ocean. Sounds of seismic and biological origin contain information regarding the underlying processes that created them. A single hydrophone records summary time-frequency information from the volume within acoustic range. Beamforming using a hydrophone array additionally produces azimuthal estimates of sound sources. A two-dimensional array and acoustic focusing produce an unambiguous two-dimensional `image' of sources. This dissertation describes the application of these techniques in three cases. The first utilizes hydrophone arrays to investigate T-phases (water-borne seismic waves) in the Philippine Sea. Ninety T-phases were recorded over a 12-day period, implying a greater number of seismic events occur than are detected by terrestrial seismic monitoring in the region. Observation of an azimuthally migrating T-phase suggests that reverberation of such sounds from bathymetric features can occur over megameter scales. In the second case, single hydrophone recordings from coral reefs in the Line Islands archipelago reveal that local ambient reef sound is spectrally similar to sounds produced by small, hard-shelled benthic invertebrates in captivity. Time-lapse photography of the reef reveals an increase in benthic invertebrate activity at sundown, consistent with an increase in sound level. The dominant acoustic phenomenon on these reefs may thus originate from the interaction between a large number of small invertebrates and the substrate. Such sounds could be used to take census of hard-shelled benthic invertebrates that are otherwise extremely difficult to survey. A two-dimensional `map' of sound production over a coral reef in the Hawaiian Islands was obtained using two-dimensional hydrophone array in the third case. Heterogeneously distributed bio-acoustic sources were generally co-located with rocky reef areas. Acoustically dominant snapping shrimp were largely restricted to one location within the area surveyed

  6. The lungs

    International Nuclear Information System (INIS)

    Macey, D.J.; Marshall, R.

    1982-01-01

    Currently emission tomography of the lungs is only practical for perfusion images with sup(99m)Tc microaggregates and ventilation images with sup(81m)Kr. The following topics are touched on: the rotating gamma camera single photon ECT system, spatial resolution and linearity, resolution in phantom studies, area and volume studies, quantitation studies, with particular reference to the authors' experience of perfusion and ventilation in investigations of pulmonary embolism. (U.K.)

  7. Hyperlucent lung

    International Nuclear Information System (INIS)

    Jimenez-Gutierrez, Florana; Soto-Quiros, Manuel E.

    2007-01-01

    Unilateral hyperlucent lung is also known as Swyer-James Syndrome, Macleod Syndrome or lobular or unilateral emphysema. It is an uncommon disease characterized by lung or unilateral lobe hiperlucency associated to an air trapping upon expiration. As regards to etiology, this syndrome is considered to be an acquired disease that appears secondary to respiratory infections during the early years of life, probably bronchiolitis and/ or viral pneumonia. The clinical presentation varies among patients. Some of them are asymptomatic, others present a history of recurrent episodes of pulmonary infections from early years of life or present effort dyspnea. The diagnosis is usually made accidentally by a chest radiograph in a child with history of respiratory infections or in an adult during a routine chest x- ray in an asymptomatic person. It is important to differentiate this syndrome from other causes of unilateral pulmonary hiperlucency on conventional chest x-rays. Few cases of Swyer-James Syndrome in children have been reported, it is presented the clinical case of a patient who had a parainfluenza 3 bronchopneumonia when he was a month and eighteen days of age. The differential diagnosis of this syndrome should be done with other thoracic entities that diminish the radiological pulmonary unilateral density. A case of a child who is the bearer of hyperlucent lung is described. (author) [es

  8. An alternative respiratory sounds classification system utilizing artificial neural networks

    Directory of Open Access Journals (Sweden)

    Rami J Oweis

    2015-04-01

    Full Text Available Background: Computerized lung sound analysis involves recording lung sound via an electronic device, followed by computer analysis and classification based on specific signal characteristics as non-linearity and nonstationarity caused by air turbulence. An automatic analysis is necessary to avoid dependence on expert skills. Methods: This work revolves around exploiting autocorrelation in the feature extraction stage. All process stages were implemented in MATLAB. The classification process was performed comparatively using both artificial neural networks (ANNs and adaptive neuro-fuzzy inference systems (ANFIS toolboxes. The methods have been applied to 10 different respiratory sounds for classification. Results: The ANN was superior to the ANFIS system and returned superior performance parameters. Its accuracy, specificity, and sensitivity were 98.6%, 100%, and 97.8%, respectively. The obtained parameters showed superiority to many recent approaches. Conclusions: The promising proposed method is an efficient fast tool for the intended purpose as manifested in the performance parameters, specifically, accuracy, specificity, and sensitivity. Furthermore, it may be added that utilizing the autocorrelation function in the feature extraction in such applications results in enhanced performance and avoids undesired computation complexities compared to other techniques.

  9. Fourth sound in relativistic superfluidity theory

    International Nuclear Information System (INIS)

    Vil'chinskij, S.I.; Fomin, P.I.

    1995-01-01

    The Lorentz-covariant equations describing propagation of the fourth sound in the relativistic theory of superfluidity are derived. The expressions for the velocity of the fourth sound are obtained. The character of oscillation in sound is determined

  10. EUVS Sounding Rocket Payload

    Science.gov (United States)

    Stern, Alan S.

    1996-01-01

    During the first half of this year (CY 1996), the EUVS project began preparations of the EUVS payload for the upcoming NASA sounding rocket flight 36.148CL, slated for launch on July 26, 1996 to observe and record a high-resolution (approx. 2 A FWHM) EUV spectrum of the planet Venus. These preparations were designed to improve the spectral resolution and sensitivity performance of the EUVS payload as well as prepare the payload for this upcoming mission. The following is a list of the EUVS project activities that have taken place since the beginning of this CY: (1) Applied a fresh, new SiC optical coating to our existing 2400 groove/mm grating to boost its reflectivity; (2) modified the Ranicon science detector to boost its detective quantum efficiency with the addition of a repeller grid; (3) constructed a new entrance slit plane to achieve 2 A FWHM spectral resolution; (4) prepared and held the Payload Initiation Conference (PIC) with the assigned NASA support team from Wallops Island for the upcoming 36.148CL flight (PIC held on March 8, 1996; see Attachment A); (5) began wavelength calibration activities of EUVS in the laboratory; (6) made arrangements for travel to WSMR to begin integration activities in preparation for the July 1996 launch; (7) paper detailing our previous EUVS Venus mission (NASA flight 36.117CL) published in Icarus (see Attachment B); and (8) continued data analysis of the previous EUVS mission 36.137CL (Spica occultation flight).

  11. Sound Clocks and Sonic Relativity

    Science.gov (United States)

    Todd, Scott L.; Menicucci, Nicolas C.

    2017-10-01

    Sound propagation within certain non-relativistic condensed matter models obeys a relativistic wave equation despite such systems admitting entirely non-relativistic descriptions. A natural question that arises upon consideration of this is, "do devices exist that will experience the relativity in these systems?" We describe a thought experiment in which `acoustic observers' possess devices called sound clocks that can be connected to form chains. Careful investigation shows that appropriately constructed chains of stationary and moving sound clocks are perceived by observers on the other chain as undergoing the relativistic phenomena of length contraction and time dilation by the Lorentz factor, γ , with c the speed of sound. Sound clocks within moving chains actually tick less frequently than stationary ones and must be separated by a shorter distance than when stationary to satisfy simultaneity conditions. Stationary sound clocks appear to be length contracted and time dilated to moving observers due to their misunderstanding of their own state of motion with respect to the laboratory. Observers restricted to using sound clocks describe a universe kinematically consistent with the theory of special relativity, despite the preferred frame of their universe in the laboratory. Such devices show promise in further probing analogue relativity models, for example in investigating phenomena that require careful consideration of the proper time elapsed for observers.

  12. Sound localization and occupational noise

    Directory of Open Access Journals (Sweden)

    Pedro de Lemos Menezes

    2014-02-01

    Full Text Available OBJECTIVE: The aim of this study was to determine the effects of occupational noise on sound localization in different spatial planes and frequencies among normal hearing firefighters. METHOD: A total of 29 adults with pure-tone hearing thresholds below 25 dB took part in the study. The participants were divided into a group of 19 firefighters exposed to occupational noise and a control group of 10 adults who were not exposed to such noise. All subjects were assigned a sound localization task involving 117 stimuli from 13 sound sources that were spatially distributed in horizontal, vertical, midsagittal and transverse planes. The three stimuli, which were square waves with fundamental frequencies of 500, 2,000 and 4,000 Hz, were presented at a sound level of 70 dB and were randomly repeated three times from each sound source. The angle between the speaker's axis in the same plane was 45°, and the distance to the subject was 1 m. RESULT: The results demonstrate that the sound localization ability of the firefighters was significantly lower (p<0.01 than that of the control group. CONCLUSION: Exposure to occupational noise, even when not resulting in hearing loss, may lead to a diminished ability to locate a sound source.

  13. Gefinex 400S (SAMPO) EM-soundings at Olkiluoto 2009

    International Nuclear Information System (INIS)

    Jokinen, T.; Lehtimaeki, J.; Korhonen, K.

    2009-09-01

    In the beginning of June 2009 Geological Survey of Finland (GTK) carried out electromagnetic (EM) frequency soundings with Gefinex 400S equipment (Sampo) in the vicinity of ONKALO at the Olkiluoto site investigation area. The EM-monitoring sounding program started in 2004 and has been repeated since yearly in the same season. The aim of the study is to monitor the variations of the groundwater properties down to 500 m depth by the changes of the electric conductivity of the earth at ONKALO and repository area. The original measurement grid was based on two 1400 m long broadside profiles, which have 200 m mutual distance and 200 m station separation. The receiver and transmitter sites are marked with stakes and the profiles were measured using 200, 500, and 800 m coil separations. The measurement program was revised in 2007 and then again in 2009. Now 15 noisy soundings were removed from the program and 3 new points were selected from the area to the east from ONKALO. The new receiver/transmitter sites, called ABC-points were marked with stakes and the points were measured using transmitter-receiver separations 200, 400 and 800 meters. In 2009 the new EM-Sampo monitoring program included 28+9 soundings. The numerous power lines and cables in the area generate local disturbances on the sounding curves, but the SN (signal to noise) ratio and the repeatability of the results is reasonably good even with long coil separations. However, most suitable for monitoring purposes are the sites without strong shallow 3D effects. Comparison of the new results to old 2004-2008 surveys shows differences on some ARD (apparent resistivity-depth) curves. Those are mainly results of the modified shallow structures. The changes in groundwater conditions based on the monitoring results seem insignificant. (orig.)

  14. Gefinex 400S (Sampo) EM-Soundings at Olkiluoto 2006

    International Nuclear Information System (INIS)

    Jokinen, T.; Lehtimaeki, J.

    2006-08-01

    In the beginning of summer 2006 Geological Survey of Finland carried out electromagnetic frequency soundings with Gefinex 400S equipment (called also Sampo) at Onkalo situated in Olkiluoto nuclear power plant area. The same soundings sites were the first time measured and marked in 2004 and repeated in 2005. The aim of the measurements is to monitor the changes of groundwater conditions by the changes of the electric conductivity of the earth at ONKALO and repository area. The measurements form two 1400 m long broadside profiles, which have 200 m mutual distance and 200 m station separation. The profiles have been measured using 200, 500, and 800 m coil separations. The total number of the soundings was 48 but at 8 stations the measurement did not succeed because of strong electromagnetic noise. The numerous power lines and the cables of the area generate local 3-D effects on the sounding curves, but the repeatability of the results is good. However, most suitable for monitoring purposes are the sites without strong 3-D effects. Comparison of results 2004-2006 shows small differences at some sounding sites. (orig.)

  15. Heart sounds analysis via esophageal stethoscope system in beagles.

    Science.gov (United States)

    Park, Sang Hi; Shin, Young Duck; Bae, Jin Ho; Kwon, Eun Jung; Lee, Tae-Soo; Shin, Ji-Yun; Kim, Yeong-Cheol; Min, Gyeong-Deuk; Kim, Myoung hwan

    2013-10-01

    Esophageal stethoscope is less invasive and easy to handling. And it gives a lot of information. The purpose of this study is to investigate the correlation of blood pressure and heart sound as measured by esophageal stethoscope. Four male beagles weighing 10 to 12 kg were selected as experimental subjects. After general anesthesia, the esophageal stethoscope was inserted. After connecting the microphone, the heart sounds were visualized and recorded through a self-developed equipment and program. The amplitudes of S1 and S2 were monitored real-time to examine changes as the blood pressure increased and decreased. The relationship between the ratios of S1 to S2 (S1/S2) and changes in blood pressure due to ephedrine was evaluated. The same experiment was performed with different concentration of isoflurane. From S1 and S2 in the inotropics experiment, a high correlation appeared with change in blood pressure in S1. The relationship between S1/S2 and change in blood pressure showed a positive correlation in each experimental subject. In the volatile anesthetics experiment, the heart sounds decreased as MAC increased. Heart sounds were analyzed successfully with the esophageal stethoscope through the self-developed program and equipment. A proportional change in heart sounds was confirmed when blood pressure was changed using inotropics or volatile anesthetics. The esophageal stethoscope can achieve the closest proximity to the heart to hear sounds in a non-invasive manner.

  16. Frog sound identification using extended k-nearest neighbor classifier

    Science.gov (United States)

    Mukahar, Nordiana; Affendi Rosdi, Bakhtiar; Athiar Ramli, Dzati; Jaafar, Haryati

    2017-09-01

    Frog sound identification based on the vocalization becomes important for biological research and environmental monitoring. As a result, different types of feature extractions and classifiers have been employed to evaluate the accuracy of frog sound identification. This paper presents a frog sound identification with Extended k-Nearest Neighbor (EKNN) classifier. The EKNN classifier integrates the nearest neighbors and mutual sharing of neighborhood concepts, with the aims of improving the classification performance. It makes a prediction based on who are the nearest neighbors of the testing sample and who consider the testing sample as their nearest neighbors. In order to evaluate the classification performance in frog sound identification, the EKNN classifier is compared with competing classifier, k -Nearest Neighbor (KNN), Fuzzy k -Nearest Neighbor (FKNN) k - General Nearest Neighbor (KGNN)and Mutual k -Nearest Neighbor (MKNN) on the recorded sounds of 15 frog species obtained in Malaysia forest. The recorded sounds have been segmented using Short Time Energy and Short Time Average Zero Crossing Rate (STE+STAZCR), sinusoidal modeling (SM), manual and the combination of Energy (E) and Zero Crossing Rate (ZCR) (E+ZCR) while the features are extracted by Mel Frequency Cepstrum Coefficient (MFCC). The experimental results have shown that the EKNCN classifier exhibits the best performance in terms of accuracy compared to the competing classifiers, KNN, FKNN, GKNN and MKNN for all cases.

  17. Fourth sound of holographic superfluids

    International Nuclear Information System (INIS)

    Yarom, Amos

    2009-01-01

    We compute fourth sound for superfluids dual to a charged scalar and a gauge field in an AdS 4 background. For holographic superfluids with condensates that have a large scaling dimension (greater than approximately two), we find that fourth sound approaches first sound at low temperatures. For condensates that a have a small scaling dimension it exhibits non-conformal behavior at low temperatures which may be tied to the non-conformal behavior of the order parameter of the superfluid. We show that by introducing an appropriate scalar potential, conformal invariance can be enforced at low temperatures.

  18. Sound intensity as a function of sound insulation partition

    OpenAIRE

    Cvetkovic , S.; Prascevic , R.

    1994-01-01

    In the modern engineering practice, the sound insulation of the partitions is the synthesis of the theory and of the experience acquired in the procedure of the field and of the laboratory measurement. The science and research public treat the sound insulation in the context of the emission and propagation of the acoustic energy in the media with the different acoustics impedance. In this paper, starting from the essence of physical concept of the intensity as the energy vector, the authors g...

  19. An Integrated Approach to Motion and Sound

    National Research Council Canada - National Science Library

    Hahn, James K; Geigel, Joe; Lee, Jong W; Gritz, Larry; Takala, Tapio; Mishra, Suneil

    1995-01-01

    Until recently, sound has been given little attention in computer graphics and related domains of computer animation and virtual environments, although sounds which are properly synchronized to motion...

  20. Lung transplantation in children. Specific aspects.

    Science.gov (United States)

    Moreno Galdó, Antonio; Solé Montserrat, Juan; Roman Broto, Antonio

    2013-12-01

    Lung transplantation has become in recent years a therapeutic option for infantswith terminal lung disease with similar results to transplantation in adults.In Spain, since 1996 114 children lung transplants have been performed; this corresponds to3.9% of the total transplant number.The most common indication in children is cystic fibrosis, which represents between 70-80% of the transplants performed in adolescents. In infants common indications areinterstitial lung disease and pulmonary hypertension.In most children a sequential double lung transplant is performed, generally with the help ofextracorporeal circulation. Lung transplantation in children presents special challenges in monitoring and follow-up, especially in infants, given the difficulty in assessing lung function and performing transbronchial biopsies.There are some more specific complications in children like postransplant lymphoproliferative syndrome or a greater severity of respiratory virus infections .After lung transplantation children usually experiment a very important improvement in their quality of life. Eighty eight per cent of children have no limitations in their activity after 3 years of transplantation.According to the registry of the International Society for Heart & Lung Transplantation (ISHLT) survival at 5 years of transplantation is 54% and at 10 years is around 35%. Copyright © 2013 SEPAR. Published by Elsevier Espana. All rights reserved.

  1. "Open lung ventilation optimizes pulmonary function during lung surgery".

    Science.gov (United States)

    Downs, John B; Robinson, Lary A; Steighner, Michael L; Thrush, David; Reich, Richard R; Räsänen, Jukka O

    2014-12-01

    We evaluated an "open lung" ventilation (OV) strategy using low tidal volumes, low respiratory rate, low FiO2, and high continuous positive airway pressure in patients undergoing major lung resections. In this phase I pilot study, twelve consecutive patients were anesthetized using conventional ventilator settings (CV) and then OV strategy during which oxygenation and lung compliance were noted. Subsequently, a lung resection was performed. Data were collected during both modes of ventilation in each patient, with each patient acting as his own control. The postoperative course was monitored for complications. Twelve patients underwent open thoracotomies for seven lobectomies and five segmentectomies. The OV strategy provided consistent one-lung anesthesia and improved static compliance (40 ± 7 versus 25 ± 4 mL/cm H2O, P = 0.002) with airway pressures similar to CV. Postresection oxygenation (SpO2/FiO2) was better during OV (433 ± 11 versus 386 ± 15, P = 0.008). All postoperative chest x-rays were free of atelectasis or infiltrates. No patient required supplemental oxygen at any time postoperatively or on discharge. The mean hospital stay was 4 ± 1 d. There were no complications or mortality. The OV strategy, previously shown to have benefits during mechanical ventilation of patients with respiratory failure, proved safe and effective in lung resection patients. Because postoperative pulmonary complications may be directly attributable to the anesthetic management, adopting an OV strategy that optimizes lung mechanics and gas exchange may help reduce postoperative problems and improve overall surgical results. A randomized trial is planned to ascertain whether this technique will reduce postoperative pulmonary complications. Copyright © 2014 Elsevier Inc. All rights reserved.

  2. Metastatic tumors of lungs

    International Nuclear Information System (INIS)

    Rozenshtraukh, L.C.; Rybakova, N.I.; Vinner, M.G.

    1987-01-01

    Roentgenologic semiotics of lung metastases and their complications, as well as peculiarities of lung metastases of separate localization tumours are presented. Definition table for primary tumour by roentgenologic aspect of lung metastases is given

  3. How Lungs Work

    Science.gov (United States)

    ... Diseases > How Lungs Work How Lungs Work The Respiratory System Your lungs are part of the respiratory system, ... your sense of smell. The Parts of the Respiratory System and How They Work Airways SINUSES are hollow ...

  4. Protecting Your Lungs

    Science.gov (United States)

    ... lung capacity. Specific breathing exercises can also help improve your lung function if you have certain lung diseases, like COPD. Exercise and breathing techniques are also great for improving your mood and helping you relax. Public Health and Your ...

  5. The science of sound recording

    CERN Document Server

    Kadis, Jay

    2012-01-01

    The Science of Sound Recording will provide you with more than just an introduction to sound and recording, it will allow you to dive right into some of the technical areas that often appear overwhelming to anyone without an electrical engineering or physics background.  The Science of Sound Recording helps you build a basic foundation of scientific principles, explaining how recording really works. Packed with valuable must know information, illustrations and examples of 'worked through' equations this book introduces the theory behind sound recording practices in a logical and prac

  6. Loose parts monitoring system

    International Nuclear Information System (INIS)

    Wakasa, Kohji; Nishida, Eiichi; Ishii, Kazuo; Yamanaka, Hiroto.

    1987-01-01

    In the loose parts monitoring system (LPMS), installed for integrity monitoring of the nuclear power plants; when there occur foreign metallic objects in the reactor primary system, including a steam generator and the piping, the sounds caused by them moving with the cooling water and thereby getting in contact with various structures are detected. Its purpose is, therefore, to detect any abnormality in the reactor plant system through such abnormal sounds due to loose or fallen supports etc., and so provide this information to the reactor operators. In principle, accelerometers are distributed in such as reactor vessel, steam generator, coolant pumps, etc., so that various sounds are collected and converted into electrical signals, followed by analysis of the data. Described are the LPMS configuration/functions, the course taken in LPMS development, future problems, etc. (Mori, K.)

  7. Visualization of Broadband Sound Sources

    OpenAIRE

    Sukhanov Dmitry; Erzakova Nadezhda

    2016-01-01

    In this paper the method of imaging of wideband audio sources based on the 2D microphone array measurements of the sound field at the same time in all the microphones is proposed. Designed microphone array consists of 160 microphones allowing to digitize signals with a frequency of 7200 Hz. Measured signals are processed using the special algorithm that makes it possible to obtain a flat image of wideband sound sources. It is shown experimentally that the visualization is not dependent on the...

  8. Statistics of natural binaural sounds.

    Directory of Open Access Journals (Sweden)

    Wiktor Młynarski

    Full Text Available Binaural sound localization is usually considered a discrimination task, where interaural phase (IPD and level (ILD disparities at narrowly tuned frequency channels are utilized to identify a position of a sound source. In natural conditions however, binaural circuits are exposed to a stimulation by sound waves originating from multiple, often moving and overlapping sources. Therefore statistics of binaural cues depend on acoustic properties and the spatial configuration of the environment. Distribution of cues encountered naturally and their dependence on physical properties of an auditory scene have not been studied before. In the present work we analyzed statistics of naturally encountered binaural sounds. We performed binaural recordings of three auditory scenes with varying spatial configuration and analyzed empirical cue distributions from each scene. We have found that certain properties such as the spread of IPD distributions as well as an overall shape of ILD distributions do not vary strongly between different auditory scenes. Moreover, we found that ILD distributions vary much weaker across frequency channels and IPDs often attain much higher values, than can be predicted from head filtering properties. In order to understand the complexity of the binaural hearing task in the natural environment, sound waveforms were analyzed by performing Independent Component Analysis (ICA. Properties of learned basis functions indicate that in natural conditions soundwaves in each ear are predominantly generated by independent sources. This implies that the real-world sound localization must rely on mechanisms more complex than a mere cue extraction.

  9. Statistics of natural binaural sounds.

    Science.gov (United States)

    Młynarski, Wiktor; Jost, Jürgen

    2014-01-01

    Binaural sound localization is usually considered a discrimination task, where interaural phase (IPD) and level (ILD) disparities at narrowly tuned frequency channels are utilized to identify a position of a sound source. In natural conditions however, binaural circuits are exposed to a stimulation by sound waves originating from multiple, often moving and overlapping sources. Therefore statistics of binaural cues depend on acoustic properties and the spatial configuration of the environment. Distribution of cues encountered naturally and their dependence on physical properties of an auditory scene have not been studied before. In the present work we analyzed statistics of naturally encountered binaural sounds. We performed binaural recordings of three auditory scenes with varying spatial configuration and analyzed empirical cue distributions from each scene. We have found that certain properties such as the spread of IPD distributions as well as an overall shape of ILD distributions do not vary strongly between different auditory scenes. Moreover, we found that ILD distributions vary much weaker across frequency channels and IPDs often attain much higher values, than can be predicted from head filtering properties. In order to understand the complexity of the binaural hearing task in the natural environment, sound waveforms were analyzed by performing Independent Component Analysis (ICA). Properties of learned basis functions indicate that in natural conditions soundwaves in each ear are predominantly generated by independent sources. This implies that the real-world sound localization must rely on mechanisms more complex than a mere cue extraction.

  10. Lung PET scan

    Science.gov (United States)

    ... Chest PET scan; Lung positron emission tomography; PET - chest; PET - lung; PET - tumor imaging; ... Grainger & Allison's Diagnostic Radiology: A Textbook of Medical Imaging . 6th ed. Philadelphia, ...

  11. Extravascular Lung Water and Acute Lung Injury

    Directory of Open Access Journals (Sweden)

    Ritesh Maharaj

    2012-01-01

    Full Text Available Acute lung injury carries a high burden of morbidity and mortality and is characterised by nonhydrostatic pulmonary oedema. The aim of this paper is to highlight the role of accurate quantification of extravascular lung water in diagnosis, management, and prognosis in “acute lung injury” and “acute respiratory distress syndrome”. Several studies have verified the accuracy of both the single and the double transpulmonary thermal indicator techniques. Both experimental and clinical studies were searched in PUBMED using the term “extravascular lung water” and “acute lung injury”. Extravascular lung water measurement offers information not otherwise available by other methods such as chest radiography, arterial blood gas, and chest auscultation at the bedside. Recent data have highlighted the role of extravascular lung water in response to treatment to guide fluid therapy and ventilator strategies. The quantification of extravascular lung water may predict mortality and multiorgan dysfunction. The limitations of the dilution method are also discussed.

  12. Computerised respiratory sounds can differentiate smokers and non-smokers.

    Science.gov (United States)

    Oliveira, Ana; Sen, Ipek; Kahya, Yasemin P; Afreixo, Vera; Marques, Alda

    2017-06-01

    Cigarette smoking is often associated with the development of several respiratory diseases however, if diagnosed early, the changes in the lung tissue caused by smoking may be reversible. Computerised respiratory sounds have shown to be sensitive to detect changes within the lung tissue before any other measure, however it is unknown if it is able to detect changes in the lungs of healthy smokers. This study investigated the differences between computerised respiratory sounds of healthy smokers and non-smokers. Healthy smokers and non-smokers were recruited from a university campus. Respiratory sounds were recorded simultaneously at 6 chest locations (right and left anterior, lateral and posterior) using air-coupled electret microphones. Airflow (1.0-1.5 l/s) was recorded with a pneumotachograph. Breathing phases were detected using airflow signals and respiratory sounds with validated algorithms. Forty-four participants were enrolled: 18 smokers (mean age 26.2, SD = 7 years; mean FEV 1 % predicted 104.7, SD = 9) and 26 non-smokers (mean age 25.9, SD = 3.7 years; mean FEV 1 % predicted 96.8, SD = 20.2). Smokers presented significantly higher frequency at maximum sound intensity during inspiration [(M = 117, SD = 16.2 Hz vs. M = 106.4, SD = 21.6 Hz; t(43) = -2.62, p = 0.0081, d z  = 0.55)], lower expiratory sound intensities (maximum intensity: [(M = 48.2, SD = 3.8 dB vs. M = 50.9, SD = 3.2 dB; t(43) = 2.68, p = 0.001, d z  = -0.78)]; mean intensity: [(M = 31.2, SD = 3.6 dB vs. M = 33.7,SD = 3 dB; t(43) = 2.42, p = 0.001, d z  = 0.75)] and higher number of inspiratory crackles (median [interquartile range] 2.2 [1.7-3.7] vs. 1.5 [1.2-2.2], p = 0.081, U = 110, r = -0.41) than non-smokers. Significant differences between computerised respiratory sounds of smokers and non-smokers have been found. Changes in respiratory sounds are often the earliest sign of disease. Thus, computerised respiratory sounds

  13. 27 CFR 9.151 - Puget Sound.

    Science.gov (United States)

    2010-04-01

    ... 27 Alcohol, Tobacco Products and Firearms 1 2010-04-01 2010-04-01 false Puget Sound. 9.151 Section... Sound. (a) Name. The name of the viticultural area described in this section is “Puget Sound.” (b) Approved maps. The appropriate maps for determining the boundary of the Puget Sound viticultural area are...

  14. Wearable Eating Habit Sensing System Using Internal Body Sound

    Science.gov (United States)

    Shuzo, Masaki; Komori, Shintaro; Takashima, Tomoko; Lopez, Guillaume; Tatsuta, Seiji; Yanagimoto, Shintaro; Warisawa, Shin'ichi; Delaunay, Jean-Jacques; Yamada, Ichiro

    Continuous monitoring of eating habits could be useful in preventing lifestyle diseases such as metabolic syndrome. Conventional methods consist of self-reporting and calculating mastication frequency based on the myoelectric potential of the masseter muscle. Both these methods are significant burdens for the user. We developed a non-invasive, wearable sensing system that can record eating habits over a long period of time in daily life. Our sensing system is composed of two bone conduction microphones placed in the ears that send internal body sound data to a portable IC recorder. Applying frequency spectrum analysis on the collected sound data, we could not only count the number of mastications during eating, but also accurately differentiate between eating, drinking, and speaking activities. This information can be used to evaluate the regularity of meals. Moreover, we were able to analyze sound features to classify the types of foods eaten by food texture.

  15. Lung pathology and exposure to radon daughters

    International Nuclear Information System (INIS)

    Saccomanno, G.

    1980-01-01

    The data presented suggest that the primary carcinogen of lung cancer in uranium miners is cigarette smoking because the incidence of lung cancer in noncigarette smokers is insignificant. In cigarette-smoking uranium miners, however, the incidence of cancer in those exposed to significant amounts of radon daughters is higher than in the smoking, nonmining population. This suggests that radon is an additive carcinogen if the lung has been injured by the cigarette-smoking carcinogen. Preliminary studies measuring DNA, T cells, and rosette inhibition immunological studies indicate closer monitoring of uranium miners' health during this occupation may be justified

  16. Intersections of lung progenitor cells, lung disease and lung cancer.

    Science.gov (United States)

    Kim, Carla F

    2017-06-30

    The use of stem cell biology approaches to study adult lung progenitor cells and lung cancer has brought a variety of new techniques to the field of lung biology and has elucidated new pathways that may be therapeutic targets in lung cancer. Recent results have begun to identify the ways in which different cell populations interact to regulate progenitor activity, and this has implications for the interventions that are possible in cancer and in a variety of lung diseases. Today's better understanding of the mechanisms that regulate lung progenitor cell self-renewal and differentiation, including understanding how multiple epigenetic factors affect lung injury repair, holds the promise for future better treatments for lung cancer and for optimising the response to therapy in lung cancer. Working between platforms in sophisticated organoid culture techniques, genetically engineered mouse models of injury and cancer, and human cell lines and specimens, lung progenitor cell studies can begin with basic biology, progress to translational research and finally lead to the beginnings of clinical trials. Copyright ©ERS 2017.

  17. Intersections of lung progenitor cells, lung disease and lung cancer

    Directory of Open Access Journals (Sweden)

    Carla F. Kim

    2017-06-01

    Full Text Available The use of stem cell biology approaches to study adult lung progenitor cells and lung cancer has brought a variety of new techniques to the field of lung biology and has elucidated new pathways that may be therapeutic targets in lung cancer. Recent results have begun to identify the ways in which different cell populations interact to regulate progenitor activity, and this has implications for the interventions that are possible in cancer and in a variety of lung diseases. Today's better understanding of the mechanisms that regulate lung progenitor cell self-renewal and differentiation, including understanding how multiple epigenetic factors affect lung injury repair, holds the promise for future better treatments for lung cancer and for optimising the response to therapy in lung cancer. Working between platforms in sophisticated organoid culture techniques, genetically engineered mouse models of injury and cancer, and human cell lines and specimens, lung progenitor cell studies can begin with basic biology, progress to translational research and finally lead to the beginnings of clinical trials.

  18. Sound engineering for diesel engines; Sound Engineering an Dieselmotoren

    Energy Technology Data Exchange (ETDEWEB)

    Enderich, A.; Fischer, R. [MAHLE Filtersysteme GmbH, Stuttgart (Germany)

    2006-07-01

    The strong acceptance for vehicles powered by turbo-charged diesel engines encourages several manufacturers to think about sportive diesel concepts. The approach of suppressing unpleasant noise by the application of distinctive insulation steps is not adequate to satisfy sportive needs. The acoustics cannot follow the engine's performance. This report documents, that it is possible to give diesel-powered vehicles a sportive sound characteristic by using an advanced MAHLE motor-sound-system with a pressure-resistant membrane and an integrated load controlled flap. With this the specific acoustic disadvantages of the diesel engine, like the ''diesel knock'' or a rough engine running can be masked. However, by the application of a motor-sound-system you must not negate the original character of the diesel engine concept, but accentuate its strong torque characteristic in the middle engine speed range. (orig.)

  19. Sound field separation with sound pressure and particle velocity measurements

    DEFF Research Database (Denmark)

    Fernandez Grande, Efren; Jacobsen, Finn; Leclère, Quentin

    2012-01-01

    separation techniques make it possible to distinguish between outgoing and incoming waves from the two sides, and thus NAH can be applied. In this paper, a separation method based on the measurement of the particle velocity in two layers and another method based on the measurement of the pressure...... and the velocity in a single layer are proposed. The two methods use an equivalent source formulation with separate transfer matrices for the outgoing and incoming waves, so that the sound from the two sides of the array can be modeled independently. A weighting scheme is proposed to account for the distance......In conventional near-field acoustic holography (NAH) it is not possible to distinguish between sound from the two sides of the array, thus, it is a requirement that all the sources are confined to only one side and radiate into a free field. When this requirement cannot be fulfilled, sound field...

  20. Sounds of silence: How to animate virtual worlds with sound

    Science.gov (United States)

    Astheimer, Peter

    1993-01-01

    Sounds are an integral and sometimes annoying part of our daily life. Virtual worlds which imitate natural environments gain a lot of authenticity from fast, high quality visualization combined with sound effects. Sounds help to increase the degree of immersion for human dwellers in imaginary worlds significantly. The virtual reality toolkit of IGD (Institute for Computer Graphics) features a broad range of standard visual and advanced real-time audio components which interpret an object-oriented definition of the scene. The virtual reality system 'Virtual Design' realized with the toolkit enables the designer of virtual worlds to create a true audiovisual environment. Several examples on video demonstrate the usage of the audio features in Virtual Design.

  1. Lung cancer

    International Nuclear Information System (INIS)

    Kato, Toshio

    1982-01-01

    Based on the own experience and world literatures, contribution of radiation in the treatment of lung cancer was reviewed and discussed. Although the patients with advanced cancer were referred to radiation usually, the results of radiotherapy were superior to those by chemotherapy. Of course the radiotherapy was a local one, radiation combined with chemotherapy was highly recommended, besides systemic administration of chemotherapeutics, special methods such as bronchial arterial infusion (BAI) and chemoembolization would be more favourable in selected patients. Treatment of undifferentiated small cell carcinoma was becoming more dependent on chemotherapy, radiation showed as excellent local control as ever. To treat locally extended cancer patients with involvement of the thoracic wall and Pancoast's syndrome, external radiation alone were not successful, interstitial radiation or a single exposure with a large dose during the thoracotomy would be promising. Finally, data indicated that aged and poor risk patients in early stage of cancer might be treated by radiation instead of unjustifiable operation. (author)

  2. Mobile sound: media art in hybrid spaces

    OpenAIRE

    Behrendt, Frauke

    2010-01-01

    The thesis explores the relationships between sound and mobility through an examination\\ud of sound art. The research engages with the intersection of sound, mobility and\\ud art through original empirical work and theoretically through a critical engagement with\\ud sound studies. In dialogue with the work of De Certeau, Lefebvre, Huhtamo and Habermas\\ud in terms of the poetics of walking, rhythms, media archeology and questions of\\ud publicness, I understand sound art as an experimental mobil...

  3. 33 CFR 167.1702 - In Prince William Sound: Prince William Sound Traffic Separation Scheme.

    Science.gov (United States)

    2010-07-01

    ... 33 Navigation and Navigable Waters 2 2010-07-01 2010-07-01 false In Prince William Sound: Prince William Sound Traffic Separation Scheme. 167.1702 Section 167.1702 Navigation and Navigable Waters COAST....1702 In Prince William Sound: Prince William Sound Traffic Separation Scheme. The Prince William Sound...

  4. Sounding the field: recent works in sound studies.

    Science.gov (United States)

    Boon, Tim

    2015-09-01

    For sound studies, the publication of a 593-page handbook, not to mention the establishment of at least one society - the European Sound Studies Association - might seem to signify the emergence of a new academic discipline. Certainly, the books under consideration here, alongside many others, testify to an intensification of concern with the aural dimensions of culture. Some of this work comes from HPS and STS, some from musicology and cultural studies. But all of it should concern members of our disciplines, as it represents a long-overdue foregrounding of the aural in how we think about the intersections of science, technology and culture.

  5. Conditioned sounds enhance visual processing.

    Directory of Open Access Journals (Sweden)

    Fabrizio Leo

    Full Text Available This psychophysics study investigated whether prior auditory conditioning influences how a sound interacts with visual perception. In the conditioning phase, subjects were presented with three pure tones ( =  conditioned stimuli, CS that were paired with positive, negative or neutral unconditioned stimuli. As unconditioned reinforcers we employed pictures (highly pleasant, unpleasant and neutral or monetary outcomes (+50 euro cents, -50 cents, 0 cents. In the subsequent visual selective attention paradigm, subjects were presented with near-threshold Gabors displayed in their left or right hemifield. Critically, the Gabors were presented in synchrony with one of the conditioned sounds. Subjects discriminated whether the Gabors were presented in their left or right hemifields. Participants determined the location more accurately when the Gabors were presented in synchrony with positive relative to neutral sounds irrespective of reinforcer type. Thus, previously rewarded relative to neutral sounds increased the bottom-up salience of the visual Gabors. Our results are the first demonstration that prior auditory conditioning is a potent mechanism to modulate the effect of sounds on visual perception.

  6. Moth hearing and sound communication

    DEFF Research Database (Denmark)

    Nakano, Ryo; Takanashi, Takuma; Surlykke, Annemarie

    2015-01-01

    Active echolocation enables bats to orient and hunt the night sky for insects. As a counter-measure against the severe predation pressure many nocturnal insects have evolved ears sensitive to ultrasonic bat calls. In moths bat-detection was the principal purpose of hearing, as evidenced by compar......Active echolocation enables bats to orient and hunt the night sky for insects. As a counter-measure against the severe predation pressure many nocturnal insects have evolved ears sensitive to ultrasonic bat calls. In moths bat-detection was the principal purpose of hearing, as evidenced...... by comparable hearing physiology with best sensitivity in the bat echolocation range, 20–60 kHz, across moths in spite of diverse ear morphology. Some eared moths subsequently developed sound-producing organs to warn/startle/jam attacking bats and/or to communicate intraspecifically with sound. Not only...... the sounds for interaction with bats, but also mating signals are within the frequency range where bats echolocate, indicating that sound communication developed after hearing by “sensory exploitation”. Recent findings on moth sound communication reveal that close-range (~ a few cm) communication with low...

  7. In vivo breast sound-speed imaging with ultrasound tomography

    Energy Technology Data Exchange (ETDEWEB)

    Huang, Lianjie [Los Alamos National Laboratory; Li, Cuiping [KARMANOS CANCER INSTITUTE; Duric, Neb [KARMANOS CANCER INSTITUTE; Littrup, Peter [KARMONOS CANCER INSTITUTE

    2009-01-01

    We discuss a bent-ray ultrasound tomography algorithm with total-variation (TV) regularization. We have applied this algorithm to 61 in vivo breast datasets collected with our in-house clinical prototype for imaging sound-speed distributions in the breast. Our analysis showed that TV regularization could preserve sharper lesion edges than the classic Tikhonov regularization. Furthermore, the image quality of our TV bent-ray sound-speed tomograms was superior to that of the straight-ray counterparts for all types of breasts within BI-RADS density categories 1-4. For all four breast types from fatty to dense, the improvements for average sharpness (in the unit of (m{center_dot} s) {sup -1}) of lesion edges in our TV bent-ray tomograms are between 2.1 to 3.4 fold compared to the straight ray tomograms. Reconstructed sound-speed tomograms illustrated that our algorithm could successfully image fatty and glandular tissues within the breast. We calculated the mean sound-speed values for fatty tissue and breast parenchyma as 1422 {+-} 9 mls (mean{+-} SD) and1487 {+-} 21 mls, respectively. Based on 32 lesions in a cohort of 61 patients, we also found that the mean sound-speed for malignant breast lesions (1548{+-}17 mls) was higher, on average, than that of benign ones (1513{+-}27 mls) (one-sided psound-speed tomograms can be used to assess breast density (, and therefore, breast cancer risk), as well as detect and help differentiate breast lesions. Finally, our sound-speed tomograms may also be a useful tool to monitor clinical response of breast cancer patients to neo-adjuvant chemotherapy.

  8. Seasonal distribution of Dall's porpoise in Prince William Sound, Alaska

    Science.gov (United States)

    Moran, John R.; O'Dell, Matthew B.; Arimitsu, Mayumi L.; Straley, Janice M.; Dickson, Danielle M. S.

    2018-01-01

    Dall's porpoise, Phocoenoides dalli, are a conspicuous predator in the Prince William Sound ecosystem, yet there has been little effort directed towards monitoring this species since the 1980s, prior to the Exxon Valdez oil spill. We used vessel-based surveys to examine the seasonal distribution of Dall's porpoise in the waters of Prince William Sound during eight years from 2007 to 2015. Over the course of 168 days and 15,653 km of survey effort, 921 Dall's porpoise were encountered in 210 groups. We estimate an encounter rate of 0.061 porpoise/km traveled or 1 porpoise encountered for every 16.5 km traveled. Dall's porpoise were found throughout the year in Prince William Sound, and used a wide range of habitats, including those not considered typical of the species, such as bays, shallow water, and nearshore waters. Dall's porpoise seasonally shifted their center of distribution from the western passages in fall to the bays of the eastern Sound in winter and spring. Dall's porpoises were widely dispersed throughout the Sound in summer. We identified potential Dall's porpoise habitat (depth, slope, and distance from shore) within Prince William Sound using generalized additive models (GAM). Dall's porpoise were found in deeper water during summer and in shallowest water during spring. We propose that their use of novel habitats is a function of reduced predation risk associated with the decline of their main predator, killer whales (Orcinus orca), following the Exxon Valdez oil spill, and the presence of overwintering and spawning Pacific herring (Clupea pallasii). While the size of the Dall's porpoise population within Prince William Sound remains unknown, our encounter rates were lower than those reported in the 1970s. Their high metabolic rate and ubiquitous presence makes them one of the more important, yet understudied, forage fish predators in the region.

  9. Staging of Lung Cancer

    Science.gov (United States)

    ... LUNG CANCER MINI-SERIES #2 Staging of Lung Cancer Once your lung cancer is diagnosed, staging tells you and your health care provider about ... at it under a microscope. The stages of lung cancer are listed as I, II, III, and IV ...

  10. Lung needle biopsy

    Science.gov (United States)

    ... if you have certain lung diseases such as emphysema. Usually, a collapsed lung after a biopsy does not need treatment. But ... any type Bullae (enlarged alveoli that occur with emphysema) Cor pulmonale (condition ... of the lung High blood pressure in the lung arteries Severe ...

  11. Sounds of space: listening to the Sun-Earth connection

    Science.gov (United States)

    Craig, N.; Mendez, B.; Luhmann, J.; Sircar, I.

    2003-04-01

    NASA's STEREO/IMPACT Mission includes an Education and Public Outreach component that seeks to offer national programs for broad audiences highlighting the mission's solar and geo-space research. In an effort to make observations of the Sun more accessible and exciting for a general audience, we look for alternative ways to represent the data. Scientists most often represent data visually in images, graphs, and movies. However, any data can also be represented as sound audible to the human ear, a process known as sonification. We will present our plans for an exciting prototype program that converts the science results of solar energetic particle data to sound. We plan to make sounds, imagery, and data available to the public through the World Wide Web where they may create their own sonifications, as well as integrate this effort to a science museum kiosk format. The kiosk station would include information on the STEREO mission and monitors showing images of the Sun from each of STEREO's two satellites. Our goal is to incorporate 3D goggles and a headset into the kiosk, allowing visitors to see the current or archived images in 3D and hear stereo sounds resulting from sonification of the corresponding data. Ultimately, we hope to collaborate with composers and create musical works inspired by these sounds and related solar images.

  12. Review of sound card photogates

    International Nuclear Information System (INIS)

    Gingl, Zoltan; Mingesz, Robert; Mellar, Janos; Makra, Peter

    2011-01-01

    Photogates are probably the most commonly used electronic instruments to aid experiments in the field of mechanics. Although they are offered by many manufacturers, they can be too expensive to be widely used in all classrooms, in multiple experiments or even at home experimentation. Today all computers have a sound card - an interface for analogue signals. It is possible to make very simple yet highly accurate photogates for cents, while much more sophisticated solutions are also available at a still very low cost. In our paper we show several experimentally tested ways of implementing sound card photogates in detail, and we also provide full-featured, free, open-source photogate software as a much more efficient experimentation tool than the usually used sound recording programs. Further information is provided on a dedicated web page, www.noise.physx.u-szeged.hu/edudev.

  13. Ultrahromatizm as a Sound Meditation

    Directory of Open Access Journals (Sweden)

    Zaytseva Marina

    2016-08-01

    Full Text Available The article scientifically substantiates the insights on the theory and the practice of using microchromatic in modern musical art, defines compositional and expressive possibilities of microtonal system in the works of composers of XXI century. It justifies the author's interpretation of the concept of “ultrahromatizm”, as a principle of musical thinking, which is connected with the sound space conception as the space-time continuum. The paper identifies the correlation of the notions “microchromatism” and “ultrahromatizm”. If microchromosome is understood, first and for most, as the technique of dividing the sound into microparticles, ultrahromatizm is interpreted as the principle of musical and artistic consciousness, as the musical focus of consciousness on the formation of the specific model of sound meditation and understanding of the world.

  14. Gefinex 400S (Sampo) EM-soundings at Olkiluoto 2008

    International Nuclear Information System (INIS)

    Jokinen, T.; Lehtimaeki, J.

    2008-09-01

    In the beginning of June 2008 Geological Survey of Finland (GTK) carried out electromagnetic frequency soundings with Gefinex 400S equipment (Sampo) in the vicinity of ONKALO at the Olkiluoto site investigation area. The same soundings sites were first time measured and marked in 2004 and has been repeated after it yearly in the same season. The aim of the measurements is to monitor the changes of groundwater conditions by the changes of the electric conductivity of the earth at ONKALO and repository area. The measurements form two 1400 m long broadside profiles, which have 200 m mutual distance and 200 m station separation. The profiles have been measured using 200, 500, and 800 m coil separations. Because of the strong electromagnetic noise all planned sites (48) could not be measured. In 2008 the measurements were performed at the sites that were successful in 2007 (43 soundings). The numerous power lines and cables in the area generate local disturbances on the sounding curves, but the signal/noise also with long coil separations and the repeatability of the results is reasonably good. However, most suitable for monitoring purposes are the sites without strong surficial 3D effects. Comparison of the results of 2004 to 2008 surveys shows differences on some ARD (Apparent resistivity-depth) curves. Those are mainly results of the modified man-made structures. The effects of changes in groundwater conditions are obviously slight. (orig.)

  15. Relationship between radiation dose and lung function in patients with lung cancer receiving radiotherapy

    International Nuclear Information System (INIS)

    Harsaker, V.; Dale, E.; Bruland, O.S.; Olsen, D.R.

    2003-01-01

    In patients with inoperable non-small cell lung cancer (NSCLC), radical radiotherapy is the treatment of choice. The dose is limited by consequential pneumonitis and lung fibrosis. Hence, a better understanding of the relationship between the dose-volume distributions and normal tissue side effects is needed. CT is a non-invasive method to monitor the development of fibrosis and pneumonitis, and spirometry is an established tool to measure lung function. NSCLC patients were included in a multicenter trial and treated with megavoltage conformal radiotherapy. In a subgroup comprising 16 patients, a total dose of 59-63 Gy with 1.8-1.9 Gy per fraction was given. Dose-volume histograms were calculated and corrected according to the linear-quadratic formula using alpha/beta=3 Gy. The patients underwent repetitive CT examinations (mean follow-up, 133 days) following radiotherapy, and pre and post treatment spirometry (mean follow-up, 240 days). A significant correlation was demonstrated between local lung dose and changes in CT numbers >30 days after treatment (p 40 Gy Gy there was a sudden increase in CT numbers at 70-90 days. Somewhat unexpectedly, the highest mean lung doses were found in patients with the least reductions in lung function (peak expiratory flow; p<0.001). The correlation between CT numbers, radiation dose and time after treatment show that CT may be used to monitor development of lung fibrosis/pneumonitis after radiotherapy for lung cancer. Paradoxically, the patients with the highest mean lung doses experienced the minimum deterioration of lung function. This may be explained by reduction in the volume of existing tumour masses obstructing the airways, leading to relief of symptoms. This finding stresses the role of radiotherapy for lung cancer, especially where the treatment aim is palliative

  16. Bacterial lung abscess

    International Nuclear Information System (INIS)

    Groskin, S.A.; Panicek, D.M.; Ewing, D.K.; Rivera, F.; Math, K.; Teixeira, J.; Heitzman, E.R.

    1987-01-01

    A retrospective review of patients with bacterial lung abscess was carried out. Demographic, clinical, and radiographical features of this patient group are compared with similar data from patients with empyema and/or cavitated lung carcinoma; differential diagnostic points are stressed. The entity of radiographically occult lung abscess is discussed. Complications associated with bacterial lung abscess are discussed. Current therapeutic options and treatment philosophy for patients with bacterial lung abscess are noted

  17. Artificial intelligence techniques used in respiratory sound analysis--a systematic review.

    Science.gov (United States)

    Palaniappan, Rajkumar; Sundaraj, Kenneth; Sundaraj, Sebastian

    2014-02-01

    Artificial intelligence (AI) has recently been established as an alternative method to many conventional methods. The implementation of AI techniques for respiratory sound analysis can assist medical professionals in the diagnosis of lung pathologies. This article highlights the importance of AI techniques in the implementation of computer-based respiratory sound analysis. Articles on computer-based respiratory sound analysis using AI techniques were identified by searches conducted on various electronic resources, such as the IEEE, Springer, Elsevier, PubMed, and ACM digital library databases. Brief descriptions of the types of respiratory sounds and their respective characteristics are provided. We then analyzed each of the previous studies to determine the specific respiratory sounds/pathology analyzed, the number of subjects, the signal processing method used, the AI techniques used, and the performance of the AI technique used in the analysis of respiratory sounds. A detailed description of each of these studies is provided. In conclusion, this article provides recommendations for further advancements in respiratory sound analysis.

  18. Making sound vortices by metasurfaces

    Energy Technology Data Exchange (ETDEWEB)

    Ye, Liping; Qiu, Chunyin, E-mail: cyqiu@whu.edu.cn; Lu, Jiuyang; Tang, Kun; Ke, Manzhu; Peng, Shasha [Key Laboratory of Artificial Micro- and Nano-structures of Ministry of Education and School of Physics and Technology, Wuhan University, Wuhan 430072 (China); Jia, Han [State Key Laboratory of Acoustics and Key Laboratory of Noise and Vibration Research, Institute of Acoustics, Chinese Academy of Sciences, Beijing 100190 (China); Liu, Zhengyou [Key Laboratory of Artificial Micro- and Nano-structures of Ministry of Education and School of Physics and Technology, Wuhan University, Wuhan 430072 (China); Institute for Advanced Studies, Wuhan University, Wuhan 430072 (China)

    2016-08-15

    Based on the Huygens-Fresnel principle, a metasurface structure is designed to generate a sound vortex beam in airborne environment. The metasurface is constructed by a thin planar plate perforated with a circular array of deep subwavelength resonators with desired phase and amplitude responses. The metasurface approach in making sound vortices is validated well by full-wave simulations and experimental measurements. Potential applications of such artificial spiral beams can be anticipated, as exemplified experimentally by the torque effect exerting on an absorbing disk.

  19. Antenna for Ultrawideband Channel Sounding

    DEFF Research Database (Denmark)

    Zhekov, Stanislav Stefanov; Tatomirescu, Alexandru; Pedersen, Gert F.

    2016-01-01

    A novel compact antenna for ultrawideband channel sounding is presented. The antenna is composed of a symmetrical biconical antenna modified by adding a cylinder and a ring to each cone. A feeding coaxial cable is employed during the simulations in order to evaluate and reduce its impact on the a......A novel compact antenna for ultrawideband channel sounding is presented. The antenna is composed of a symmetrical biconical antenna modified by adding a cylinder and a ring to each cone. A feeding coaxial cable is employed during the simulations in order to evaluate and reduce its impact...

  20. Visualization of Broadband Sound Sources

    Directory of Open Access Journals (Sweden)

    Sukhanov Dmitry

    2016-01-01

    Full Text Available In this paper the method of imaging of wideband audio sources based on the 2D microphone array measurements of the sound field at the same time in all the microphones is proposed. Designed microphone array consists of 160 microphones allowing to digitize signals with a frequency of 7200 Hz. Measured signals are processed using the special algorithm that makes it possible to obtain a flat image of wideband sound sources. It is shown experimentally that the visualization is not dependent on the waveform, but determined by the bandwidth. Developed system allows to visualize sources with a resolution of up to 10 cm.

  1. The Multisensory Sound Lab: Sounds You Can See and Feel.

    Science.gov (United States)

    Lederman, Norman; Hendricks, Paula

    1994-01-01

    A multisensory sound lab has been developed at the Model Secondary School for the Deaf (District of Columbia). A special floor allows vibrations to be felt, and a spectrum analyzer displays frequencies and harmonics visually. The lab is used for science education, auditory training, speech therapy, music and dance instruction, and relaxation…

  2. Sound symbolism: the role of word sound in meaning.

    Science.gov (United States)

    Svantesson, Jan-Olof

    2017-09-01

    The question whether there is a natural connection between sound and meaning or if they are related only by convention has been debated since antiquity. In linguistics, it is usually taken for granted that 'the linguistic sign is arbitrary,' and exceptions like onomatopoeia have been regarded as marginal phenomena. However, it is becoming more and more clear that motivated relations between sound and meaning are more common and important than has been thought. There is now a large and rapidly growing literature on subjects as ideophones (or expressives), words that describe how a speaker perceives a situation with the senses, and phonaesthemes, units like English gl-, which occur in many words that share a meaning component (in this case 'light': gleam, glitter, etc.). Furthermore, psychological experiments have shown that sound symbolism in one language can be understood by speakers of other languages, suggesting that some kinds of sound symbolism are universal. WIREs Cogn Sci 2017, 8:e1441. doi: 10.1002/wcs.1441 For further resources related to this article, please visit the WIREs website. © 2017 Wiley Periodicals, Inc.

  3. Offshore dredger sounds: Source levels, sound maps, and risk assessment

    NARCIS (Netherlands)

    Jong, C.A.F. de; Ainslie, M.A.; Heinis, F.; Janmaat, J.

    2016-01-01

    The underwater sound produced during construction of the Port of Rotterdam harbor extension (Maasvlakte 2) was measured, with emphasis on the contribution of the trailing suction hopper dredgers during their various activities: dredging, transport, and discharge of sediment. Measured source levels

  4. Automatic adventitious respiratory sound analysis: A systematic review.

    Directory of Open Access Journals (Sweden)

    Renard Xaviero Adhi Pramono

    Full Text Available Automatic detection or classification of adventitious sounds is useful to assist physicians in diagnosing or monitoring diseases such as asthma, Chronic Obstructive Pulmonary Disease (COPD, and pneumonia. While computerised respiratory sound analysis, specifically for the detection or classification of adventitious sounds, has recently been the focus of an increasing number of studies, a standardised approach and comparison has not been well established.To provide a review of existing algorithms for the detection or classification of adventitious respiratory sounds. This systematic review provides a complete summary of methods used in the literature to give a baseline for future works.A systematic review of English articles published between 1938 and 2016, searched using the Scopus (1938-2016 and IEEExplore (1984-2016 databases. Additional articles were further obtained by references listed in the articles found. Search terms included adventitious sound detection, adventitious sound classification, abnormal respiratory sound detection, abnormal respiratory sound classification, wheeze detection, wheeze classification, crackle detection, crackle classification, rhonchi detection, rhonchi classification, stridor detection, stridor classification, pleural rub detection, pleural rub classification, squawk detection, and squawk classification.Only articles were included that focused on adventitious sound detection or classification, based on respiratory sounds, with performance reported and sufficient information provided to be approximately repeated.Investigators extracted data about the adventitious sound type analysed, approach and level of analysis, instrumentation or data source, location of sensor, amount of data obtained, data management, features, methods, and performance achieved.A total of 77 reports from the literature were included in this review. 55 (71.43% of the studies focused on wheeze, 40 (51.95% on crackle, 9 (11.69% on stridor, 9

  5. Lung Cancer—Patient Version

    Science.gov (United States)

    The two main types of lung cancer are non-small cell lung cancer and small cell lung cancer. Smoking causes most lung cancers, but nonsmokers can also develop lung cancer. Start here to find information on lung cancer treatment, causes and prevention, screening, research, and statistics on lung cancer.

  6. Sound Exposure of Symphony Orchestra Musicians

    DEFF Research Database (Denmark)

    Schmidt, Jesper Hvass; Pedersen, Ellen Raben; Juhl, Peter Møller

    2011-01-01

    dBA and their left ear was exposed 4.6 dB more than the right ear. Percussionists were exposed to high sound peaks >115 dBC but less continuous sound exposure was observed in this group. Musicians were exposed up to LAeq8h of 92 dB and a majority of musicians were exposed to sound levels exceeding......Background: Assessment of sound exposure by noise dosimetry can be challenging especially when measuring the exposure of classical orchestra musicians where sound originate from many different instruments. A new measurement method of bilateral sound exposure of classical musicians was developed...... and used to characterize sound exposure of the left and right ear simultaneously in two different symphony orchestras.Objectives: To measure binaural sound exposure of professional classical musicians and to identify possible exposure risk factors of specific musicians.Methods: Sound exposure was measured...

  7. An acoustical model based monitoring network

    NARCIS (Netherlands)

    Wessels, P.W.; Basten, T.G.H.; Eerden, F.J.M. van der

    2010-01-01

    In this paper the approach for an acoustical model based monitoring network is demonstrated. This network is capable of reconstructing a noise map, based on the combination of measured sound levels and an acoustic model of the area. By pre-calculating the sound attenuation within the network the

  8. Vocal Imitations of Non-Vocal Sounds

    Science.gov (United States)

    Houix, Olivier; Voisin, Frédéric; Misdariis, Nicolas; Susini, Patrick

    2016-01-01

    Imitative behaviors are widespread in humans, in particular whenever two persons communicate and interact. Several tokens of spoken languages (onomatopoeias, ideophones, and phonesthemes) also display different degrees of iconicity between the sound of a word and what it refers to. Thus, it probably comes at no surprise that human speakers use a lot of imitative vocalizations and gestures when they communicate about sounds, as sounds are notably difficult to describe. What is more surprising is that vocal imitations of non-vocal everyday sounds (e.g. the sound of a car passing by) are in practice very effective: listeners identify sounds better with vocal imitations than with verbal descriptions, despite the fact that vocal imitations are inaccurate reproductions of a sound created by a particular mechanical system (e.g. a car driving by) through a different system (the voice apparatus). The present study investigated the semantic representations evoked by vocal imitations of sounds by experimentally quantifying how well listeners could match sounds to category labels. The experiment used three different types of sounds: recordings of easily identifiable sounds (sounds of human actions and manufactured products), human vocal imitations, and computational “auditory sketches” (created by algorithmic computations). The results show that performance with the best vocal imitations was similar to the best auditory sketches for most categories of sounds, and even to the referent sounds themselves in some cases. More detailed analyses showed that the acoustic distance between a vocal imitation and a referent sound is not sufficient to account for such performance. Analyses suggested that instead of trying to reproduce the referent sound as accurately as vocally possible, vocal imitations focus on a few important features, which depend on each particular sound category. These results offer perspectives for understanding how human listeners store and access long

  9. Problems in nonlinear acoustics: Scattering of sound by sound, parametric receiving arrays, nonlinear effects in asymmetric sound beams and pulsed finite amplitude sound beams

    Science.gov (United States)

    Hamilton, Mark F.

    1989-08-01

    Four projects are discussed in this annual summary report, all of which involve basic research in nonlinear acoustics: Scattering of Sound by Sound, a theoretical study of two nonconlinear Gaussian beams which interact to produce sum and difference frequency sound; Parametric Receiving Arrays, a theoretical study of parametric reception in a reverberant environment; Nonlinear Effects in Asymmetric Sound Beams, a numerical study of two dimensional finite amplitude sound fields; and Pulsed Finite Amplitude Sound Beams, a numerical time domain solution of the KZK equation.

  10. Computerized Respiratory Sounds: Novel Outcomes for Pulmonary Rehabilitation in COPD.

    Science.gov (United States)

    Jácome, Cristina; Marques, Alda

    2017-02-01

    Computerized respiratory sounds are a simple and noninvasive measure to assess lung function. Nevertheless, their potential to detect changes after pulmonary rehabilitation (PR) is unknown and needs clarification if respiratory acoustics are to be used in clinical practice. Thus, this study investigated the short- and mid-term effects of PR on computerized respiratory sounds in subjects with COPD. Forty-one subjects with COPD completed a 12-week PR program and a 3-month follow-up. Secondary outcome measures included dyspnea, self-reported sputum, FEV 1 , exercise tolerance, self-reported physical activity, health-related quality of life, and peripheral muscle strength. Computerized respiratory sounds, the primary outcomes, were recorded at right/left posterior chest using 2 stethoscopes. Air flow was recorded with a pneumotachograph. Normal respiratory sounds, crackles, and wheezes were analyzed with validated algorithms. There was a significant effect over time in all secondary outcomes, with the exception of FEV 1 and of the impact domain of the St George Respiratory Questionnaire. Inspiratory and expiratory median frequencies of normal respiratory sounds in the 100-300 Hz band were significantly lower immediately (-2.3 Hz [95% CI -4 to -0.7] and -1.9 Hz [95% CI -3.3 to -0.5]) and at 3 months (-2.1 Hz [95% CI -3.6 to -0.7] and -2 Hz [95% CI -3.6 to -0.5]) post-PR. The mean number of expiratory crackles (-0.8, 95% CI -1.3 to -0.3) and inspiratory wheeze occupation rate (median 5.9 vs 0) were significantly lower immediately post-PR. Computerized respiratory sounds were sensitive to short- and mid-term effects of PR in subjects with COPD. These findings are encouraging for the clinical use of respiratory acoustics. Future research is needed to strengthen these findings and explore the potential of computerized respiratory sounds to assess the effectiveness of other clinical interventions in COPD. Copyright © 2017 by Daedalus Enterprises.

  11. Lung structure and function relation in systemic sclerosis: Application of lung densitometry

    Energy Technology Data Exchange (ETDEWEB)

    Ninaber, Maarten K., E-mail: m.k.ninaber@lumc.nl [Department of Pulmonology, Leiden University Medical Center, Albinusdreef 2, 2333ZA Leiden (Netherlands); Stolk, Jan; Smit, Jasper; Le Roy, Ernest J. [Department of Pulmonology, Leiden University Medical Center, Albinusdreef 2, 2333ZA Leiden (Netherlands); Kroft, Lucia J.M. [Department of Radiology, Leiden University Medical Center, Albinusdreef 2, 2333ZA Leiden (Netherlands); Els Bakker, M. [Division of Image Processing, Radiology, Leiden University Medical Center, Albinusdreef 2, 2333ZA Leiden (Netherlands); Vries Bouwstra, Jeska K. de; Schouffoer, Anne A. [Department of Rheumatology, Leiden University Medical Center, Albinusdreef 2, 2333ZA Leiden (Netherlands); Staring, Marius; Stoel, Berend C. [Division of Image Processing, Radiology, Leiden University Medical Center, Albinusdreef 2, 2333ZA Leiden (Netherlands)

    2015-05-15

    Highlights: • A quantitative CT parameter of lung parenchyma in systemic sclerosis is presented. • We examine the optimal percentage threshold for the percentile density. • The 85th percentile density threshold correlated significantly with lung function. • A lung structure–function relation is confirmed. • We report applicability of Perc85 in progression mapping of interstitial lung disease. - Abstract: Introduction: Interstitial lung disease occurs frequently in patients with systemic sclerosis (SSc). Quantitative computed tomography (CT) densitometry using the percentile density method may provide a sensitive assessment of lung structure for monitoring parenchymal damage. Therefore, we aimed to evaluate the optimal percentile density score in SSc by quantitative CT densitometry, against pulmonary function. Material and methods: We investigated 41 SSc patients by chest CT scan, spirometry and gas transfer tests. Lung volumes and the nth percentile density (between 1 and 99%) of the entire lungs were calculated from CT histograms. The nth percentile density is defined as the threshold value of densities expressed in Hounsfield units. A prerequisite for an optimal percentage was its correlation with baseline DLCO %predicted. Two patients showed distinct changes in lung function 2 years after baseline. We obtained CT scans from these patients and performed progression analysis. Results: Regression analysis for the relation between DLCO %predicted and the nth percentile density was optimal at 85% (Perc85). There was significant agreement between Perc85 and DLCO %predicted (R = −0.49, P = 0.001) and FVC %predicted (R = −0.64, P < 0.001). Two patients showed a marked change in Perc85 over a 2 year period, but the localization of change differed clearly. Conclusions: We identified Perc85 as optimal lung density parameter, which correlated significantly with DLCO and FVC, confirming a lung parenchymal structure–function relation in SSc. This provides

  12. Lung structure and function relation in systemic sclerosis: Application of lung densitometry

    International Nuclear Information System (INIS)

    Ninaber, Maarten K.; Stolk, Jan; Smit, Jasper; Le Roy, Ernest J.; Kroft, Lucia J.M.; Els Bakker, M.; Vries Bouwstra, Jeska K. de; Schouffoer, Anne A.; Staring, Marius; Stoel, Berend C.

    2015-01-01

    Highlights: • A quantitative CT parameter of lung parenchyma in systemic sclerosis is presented. • We examine the optimal percentage threshold for the percentile density. • The 85th percentile density threshold correlated significantly with lung function. • A lung structure–function relation is confirmed. • We report applicability of Perc85 in progression mapping of interstitial lung disease. - Abstract: Introduction: Interstitial lung disease occurs frequently in patients with systemic sclerosis (SSc). Quantitative computed tomography (CT) densitometry using the percentile density method may provide a sensitive assessment of lung structure for monitoring parenchymal damage. Therefore, we aimed to evaluate the optimal percentile density score in SSc by quantitative CT densitometry, against pulmonary function. Material and methods: We investigated 41 SSc patients by chest CT scan, spirometry and gas transfer tests. Lung volumes and the nth percentile density (between 1 and 99%) of the entire lungs were calculated from CT histograms. The nth percentile density is defined as the threshold value of densities expressed in Hounsfield units. A prerequisite for an optimal percentage was its correlation with baseline DLCO %predicted. Two patients showed distinct changes in lung function 2 years after baseline. We obtained CT scans from these patients and performed progression analysis. Results: Regression analysis for the relation between DLCO %predicted and the nth percentile density was optimal at 85% (Perc85). There was significant agreement between Perc85 and DLCO %predicted (R = −0.49, P = 0.001) and FVC %predicted (R = −0.64, P < 0.001). Two patients showed a marked change in Perc85 over a 2 year period, but the localization of change differed clearly. Conclusions: We identified Perc85 as optimal lung density parameter, which correlated significantly with DLCO and FVC, confirming a lung parenchymal structure–function relation in SSc. This provides

  13. Sound intensity and its measurement

    DEFF Research Database (Denmark)

    Jacobsen, Finn

    1997-01-01

    The paper summarises the basic theory of sound intensity and its measurement and gives an overview of the state of the art with particular emphasis on recent developments in the field. Eighty references are given, most of which to literature published in the past two years. The paper describes...

  14. Sound Stories for General Music

    Science.gov (United States)

    Cardany, Audrey Berger

    2013-01-01

    Language and music literacy share a similar process of understanding that progresses from sensory experience to symbolic representation. The author identifies Bruner’s modes of understanding as they relate to using narrative in the music classroom to enhance music reading at iconic and symbolic levels. Two sound stories are included for…

  15. Sound / Märt Milter

    Index Scriptorium Estoniae

    Milter, Märt

    1999-01-01

    Plaatide "Hip Hop Forever. Mixed by Kenny Dope", "Permaculture", Ronnye & Clyde "In Glorious Black and Blue", "E-Z Rollers presents Drumfunk Hooliganz. Liquid Cooled Tunez From The Original Superfly Drum & Bass Generation", Iron Savior "Unification", Peter Thomas Sound Orchestra "Futuremuzik", "Sushi 4004.The Return Of Spectacular Japanese Clubpop"

  16. Intercepting a sound without vision

    Science.gov (United States)

    Vercillo, Tiziana; Tonelli, Alessia; Gori, Monica

    2017-01-01

    Visual information is extremely important to generate internal spatial representations. In the auditory modality, the absence of visual cues during early infancy does not preclude the development of some spatial strategies. However, specific spatial abilities might result impaired. In the current study, we investigated the effect of early visual deprivation on the ability to localize static and moving auditory stimuli by comparing sighted and early blind individuals’ performance in different spatial tasks. We also examined perceptual stability in the two groups of participants by matching localization accuracy in a static and a dynamic head condition that involved rotational head movements. Sighted participants accurately localized static and moving sounds. Their localization ability remained unchanged after rotational movements of the head. Conversely, blind participants showed a leftward bias during the localization of static sounds and a little bias for moving sounds. Moreover, head movements induced a significant bias in the direction of head motion during the localization of moving sounds. These results suggest that internal spatial representations might be body-centered in blind individuals and that in sighted people the availability of visual cues during early infancy may affect sensory-motor interactions. PMID:28481939

  17. Towards an open sound card

    DEFF Research Database (Denmark)

    Dimitrov, Smilen; Serafin, Stefania

    2011-01-01

    The architecture of a sound card can, in simple terms, be described as an electronic board containing a digital bus interface hardware, and analog-to-digital (A/D) and digital-to-analog (D/A) converters; then, a soundcard driver software on a personal computer's (PC) operating system (OS) can con...

  18. Sound Probabilistic #SAT with Projection

    Directory of Open Access Journals (Sweden)

    Vladimir Klebanov

    2016-10-01

    Full Text Available We present an improved method for a sound probabilistic estimation of the model count of a boolean formula under projection. The problem solved can be used to encode a variety of quantitative program analyses, such as concerning security of resource consumption. We implement the technique and discuss its application to quantifying information flow in programs.

  19. Lung growth and development.

    Science.gov (United States)

    Joshi, Suchita; Kotecha, Sailesh

    2007-12-01

    Human lung growth starts as a primitive lung bud in early embryonic life and undergoes several morphological stages which continue into postnatal life. Each stage of lung growth is a result of complex and tightly regulated events governed by physical, environmental, hormonal and genetic factors. Fetal lung liquid and fetal breathing movements are by far the most important determinants of lung growth. Although timing of the stages of lung growth in animals do not mimic that of human, numerous animal studies, mainly on sheep and rat, have given us a better understanding of the regulators of lung growth. Insight into the genetic basis of lung growth has helped us understand and improve management of complex life threatening congenital abnormalities such as congenital diaphragmatic hernia and pulmonary hypoplasia. Although advances in perinatal medicine have improved survival of preterm infants, premature birth is perhaps still the most important factor for adverse lung growth.

  20. Epidemiology of Lung Cancer

    Science.gov (United States)

    Brock, Malcolm V.; Ford, Jean G.; Samet, Jonathan M.; Spivack, Simon D.

    2013-01-01

    Background: Ever since a lung cancer epidemic emerged in the mid-1900s, the epidemiology of lung cancer has been intensively investigated to characterize its causes and patterns of occurrence. This report summarizes the key findings of this research. Methods: A detailed literature search provided the basis for a narrative review, identifying and summarizing key reports on population patterns and factors that affect lung cancer risk. Results: Established environmental risk factors for lung cancer include smoking cigarettes and other tobacco products and exposure to secondhand tobacco smoke, occupational lung carcinogens, radiation, and indoor and outdoor air pollution. Cigarette smoking is the predominant cause of lung cancer and the leading worldwide cause of cancer death. Smoking prevalence in developing nations has increased, starting new lung cancer epidemics in these nations. A positive family history and acquired lung disease are examples of host factors that are clinically useful risk indicators. Risk prediction models based on lung cancer risk factors have been developed, but further refinement is needed to provide clinically useful risk stratification. Promising biomarkers of lung cancer risk and early detection have been identified, but none are ready for broad clinical application. Conclusions: Almost all lung cancer deaths are caused by cigarette smoking, underscoring the need for ongoing efforts at tobacco control throughout the world. Further research is needed into the reasons underlying lung cancer disparities, the causes of lung cancer in never smokers, the potential role of HIV in lung carcinogenesis, and the development of biomarkers. PMID:23649439

  1. Relationship between thoracic auscultation and lung pathology detected by ultrasonography in sheep.

    Science.gov (United States)

    Scott, Phil; Collie, Dave; McGorum, Bruce; Sargison, Neil

    2010-10-01

    The utility of routine auscultation to detect and characterise the nature of a range of superficial lung and pleural pathologies in domestic sheep was assessed using ultrasonographic examination to indicate and localise pathologies pre-mortem. Necropsy examination was then used to fully characterise the nature and extent of the lesions. Auscultation recordings were made from 10 normal sheep with no clinical evidence of respiratory disease and with absence of significant superficial lung pathology, which was confirmed initially by ultrasound examination and subsequently at necropsy examination. A further two sheep with endotoxaemia and 30 sheep with well-defined lung lesions were also examined. Increased audibility of normal lung sounds in 4/10 normal sheep was associated with tachypnoea as a consequence of handling and transport during hot weather and was also observed in the two sheep with endotoxaemia. Moderate to severe coarse crackles detected in all advanced cases of ovine pulmonary adenocarcinoma (n=16) were audible over an area larger than the lesion distribution identified during ultrasound examination, and confirmed later at necropsy. Auscultation did not detect abnormal sounds in any of the five sheep with focal pleural abscesses (up to 10 cm diameter). Unilateral pyothorax caused attenuation of sounds relative to the contra-lateral normal lung in all three sheep with this condition. Marked fibrinous pleurisy caused attenuation of sounds relative to normal areas of lung in six sheep. No sounds resembling the description of pleural frictions rubs were heard in the sheep with marked fibrinous pleurisy (n=6) or associated with focal pleural abscesses (n=5). Routine interpretation of auscultated sound did not allow the presence of superficial lung pathology or its distribution to be accurately defined in the respiratory diseases represented in this study. Copyright © 2009 Elsevier Ltd. All rights reserved.

  2. Personal sleep pattern visualization using sequence-based kernel self-organizing map on sound data.

    Science.gov (United States)

    Wu, Hongle; Kato, Takafumi; Yamada, Tomomi; Numao, Masayuki; Fukui, Ken-Ichi

    2017-07-01

    We propose a method to discover sleep patterns via clustering of sound events recorded during sleep. The proposed method extends the conventional self-organizing map algorithm by kernelization and sequence-based technologies to obtain a fine-grained map that visualizes the distribution and changes of sleep-related events. We introduced features widely applied in sound processing and popular kernel functions to the proposed method to evaluate and compare performance. The proposed method provides a new aspect of sleep monitoring because the results demonstrate that sound events can be directly correlated to an individual's sleep patterns. In addition, by visualizing the transition of cluster dynamics, sleep-related sound events were found to relate to the various stages of sleep. Therefore, these results empirically warrant future study into the assessment of personal sleep quality using sound data. Copyright © 2017 Elsevier B.V. All rights reserved.

  3. Intercomparison of JAERI Torso Phantom lung sets

    International Nuclear Information System (INIS)

    Kramer, Gary H.; Hauck, Barry M.

    2000-01-01

    During the course of an IAEA sponsored In Vivo intercomparison using the JAERI phantom the Human Monitoring Laboratory was able to intercompare thirteen lung sets made by three suppliers. One set consisted of sliced lungs with planar inserts containing different radionuclides. The others consisted of whole lung sets with the activity homogeneously distributed throughout the tissue substitute material. Radionuclides in the study were: natural uranium, 3% enriched uranium, 241 Am, 238 Pu, 239 Pu, 152 Eu, and 232 Th Except for the 241 Am (59.5 keV) and occasionally one of the 232 Th (209 keV) photopeaks, the lung sets that had radioactivity homogeneously distributed throughout the tissue equivalent lung tissue material showed good agreement. The 241 Am lung set gave a counting efficiency that appeared 25% too high for all overlay plate configurations. This was observed by other participants. It exemplifies that the manufacture of tissue substitute lung sets is still something of a black art. Despite all precautions, this lung set is either inhomogeneous or has had the wrong activity added. Heterogeneity can lead to an error in the activity estimate of a factor of three if the activity was severely localised due to improper mixing. A factor of 1.25, which appears to be the discrepancy, could easily be explained in this way. It will not be known for some time, however, what the true reason is as the participants are still waiting for the destructive analysis of this lung set to determine the 'true' activity. The sliced lungs ( 241 Am, 152 Eu, and U-nat) manufactured by the Human Monitoring Laboratory are in excellent agreement with the other lung sets. The advantages of sliced lung sets and planar sources are manifold. Activity can be distributed in a known and reproducible manner to mimic either a homogeneous or heterogeneous distribution in the lung. Short lived radionuclides can be used. Cost is much less than purchasing or manufacturing lung sets that have the

  4. Urban sound energy reduction by means of sound barriers

    Directory of Open Access Journals (Sweden)

    Iordache Vlad

    2018-01-01

    Full Text Available In urban environment, various heating ventilation and air conditioning appliances designed to maintain indoor comfort become urban acoustic pollution vectors due to the sound energy produced by these equipment. The acoustic barriers are the recommended method for the sound energy reduction in urban environment. The current sizing method of these acoustic barriers is too difficult and it is not practical for any 3D location of the noisy equipment and reception point. In this study we will develop based on the same method a new simplified tool for acoustic barriers sizing, maintaining the same precision characteristic to the classical method. Abacuses for acoustic barriers sizing are built that can be used for different 3D locations of the source and the reception points, for several frequencies and several acoustic barrier heights. The study case presented in the article represents a confirmation for the rapidity and ease of use of these abacuses in the design of the acoustic barriers.

  5. Urban sound energy reduction by means of sound barriers

    Science.gov (United States)

    Iordache, Vlad; Ionita, Mihai Vlad

    2018-02-01

    In urban environment, various heating ventilation and air conditioning appliances designed to maintain indoor comfort become urban acoustic pollution vectors due to the sound energy produced by these equipment. The acoustic barriers are the recommended method for the sound energy reduction in urban environment. The current sizing method of these acoustic barriers is too difficult and it is not practical for any 3D location of the noisy equipment and reception point. In this study we will develop based on the same method a new simplified tool for acoustic barriers sizing, maintaining the same precision characteristic to the classical method. Abacuses for acoustic barriers sizing are built that can be used for different 3D locations of the source and the reception points, for several frequencies and several acoustic barrier heights. The study case presented in the article represents a confirmation for the rapidity and ease of use of these abacuses in the design of the acoustic barriers.

  6. Juvenile Pacific Salmon in Puget Sound

    National Research Council Canada - National Science Library

    Fresh, Kurt L

    2006-01-01

    Puget sound salmon (genus Oncorhynchus) spawn in freshwater and feed, grow and mature in marine waters, During their transition from freshwater to saltwater, juvenile salmon occupy nearshore ecosystems in Puget Sound...

  7. Dredged Material Management in Long Island Sound

    Science.gov (United States)

    Information on Western and Central Long Island Sound Dredged Material Disposal Sites including the Dredged Material Management Plan and Regional Dredging Team. Information regarding the Eastern Long Island Sound Selected Site including public meetings.

  8. Noninvasive monitoring of the genetic evolution of EGFR-mutant non-small-cell lung cancer by analyzing circulating tumor DNA during combination chemotherapy with gefitinib and pemetrexed or S-1

    Directory of Open Access Journals (Sweden)

    Nakahara Y

    2016-08-01

    Full Text Available Yoshiro Nakahara,1,2 Yusuke Takagi,1,3 Yukio Hosomi,1 Akiko Kagei,4 Tomohiro Yamamoto,4 Takeshi Sawada,5 Makiko Yomota,1 Yusuke Okuma,1 Shinichiro Mikura,1,6 Tatsuru Okamura1 1Department of Thoracic Oncology and Respiratory Medicine, Tokyo Metropolitan Cancer and Infectious Diseases Center Komagome Hospital, Tokyo, 2Department of Respiratory Medicine, Kitasato University School of Medicine, Sagamihara, 3Oncology Scientific Affairs, Merck Sharp & Dohme Corp, 4GeneticLab Co., Ltd., Sapporo, 5Department of Medical Oncology, Tokyo Metropolitan Cancer and Infectious Diseases Center Komagome Hospital, Tokyo, 6Department of Respiratory Medicine, Fujieda Municipal General Hospital, Fujieda, Japan Background: Repetitive genotyping is useful to assess the genetic evolution of non-small-cell lung cancer (NSCLC during treatment, but the need for sampling by biopsy is a major obstacle. Digital polymerase chain reaction (PCR is a promising procedure for the detection of mutant alleles in plasma of cancer patients.Methods: This prospective study enrolled patients with NSCLC and known epidermal growth factor receptor (EGFR mutations and who had experienced disease progression during ongoing EGFR-tyrosine kinase inhibitor (TKI therapy. Eligible patients received daily gefitinib and either pemetrexed or S-1 every 3 weeks until disease progression or the development of unacceptable toxicity. Peripheral blood was collected before and after the combination therapy for digital PCR and hepatocyte growth factor measurement.Results: From May 2012 to January 2014, nine patients with a median age of 67 (range 52–80 years were enrolled. Patterns of disease progression during adjacent EGFR-TKI therapy were acquired resistance, observed in seven patients, and primary resistance, observed in two patients. Known EGFR mutations were detected in plasma samples of six (67% patients at study enrollment. Of these, T790M mutation was concurrently detected in three (50% patients

  9. Genetics Home Reference: lung cancer

    Science.gov (United States)

    ... Share: Email Facebook Twitter Home Health Conditions Lung cancer Lung cancer Printable PDF Open All Close All Enable Javascript ... cancer, childhood Additional NIH Resources (3 links) National Cancer Institute: Lung Cancer Overview National Cancer Institute: Lung Cancer Prevention ...

  10. Radiation Therapy for Lung Cancer

    Science.gov (United States)

    ... is almost always due to smoking. TREATING LUNG CANCER Lung cancer treatment depends on several factors, including the ... org TARGETING CANCER CARE Radiation Therapy for Lung Cancer Lung cancer is the second most common cancer in ...

  11. The Influence of Fundamental Frequency and Sound Pressure Level Range on Breathing Patterns in Female Classical Singing

    Science.gov (United States)

    Collyer, Sally; Thorpe, C. William; Callaghan, Jean; Davis, Pamela J.

    2008-01-01

    Purpose: This study investigated the influence of fundamental frequency (F0) and sound pressure level (SPL) range on respiratory behavior in classical singing. Method: Five trained female singers performed an 8-s messa di voce (a crescendo and decrescendo on one F0) across their musical F0 range. Lung volume (LV) change was estimated, and…

  12. Marine Animal Sound Database. Twelve Years of Tracking 52-Hz Whale Calls from a Unique Source in the North Pacific

    National Research Council Canada - National Science Library

    Watkins, William

    2004-01-01

    Long-term monitoring of underwater sounds using U.S. Navy SOSUS and other hydrophone arrays allowed us to follow the seasonal distribution of underwater calls produced by blue, fin and humpback whales across the North Pacific...

  13. A Lexical Analysis of Environmental Sound Categories

    Science.gov (United States)

    Houix, Olivier; Lemaitre, Guillaume; Misdariis, Nicolas; Susini, Patrick; Urdapilleta, Isabel

    2012-01-01

    In this article we report on listener categorization of meaningful environmental sounds. A starting point for this study was the phenomenological taxonomy proposed by Gaver (1993b). In the first experimental study, 15 participants classified 60 environmental sounds and indicated the properties shared by the sounds in each class. In a second…

  14. Film sound in preservation and presentation

    NARCIS (Netherlands)

    Campanini, S.

    2014-01-01

    What is the nature of film sound? How does it change through time? How can film sound be conceptually defined? To address these issues, this work assumes the perspective of film preservation and presentation practices, describing the preservation of early sound systems, as well as the presentation

  15. Measuring the 'complexity'of sound

    Indian Academy of Sciences (India)

    Sounds in the natural environment form an important class of biologically relevant nonstationary signals. We propose a dynamic spectral measure to characterize the spectral dynamics of such non-stationary sound signals and classify them based on rate of change of spectral dynamics. We categorize sounds with slowly ...

  16. Sounds in one-dimensional superfluid helium

    International Nuclear Information System (INIS)

    Um, C.I.; Kahng, W.H.; Whang, E.H.; Hong, S.K.; Oh, H.G.; George, T.F.

    1989-01-01

    The temperature variations of first-, second-, and third-sound velocity and attenuation coefficients in one-dimensional superfluid helium are evaluated explicitly for very low temperatures and frequencies (ω/sub s/tau 2 , and the ratio of second sound to first sound becomes unity as the temperature decreases to absolute zero

  17. Sound-Symbolism Boosts Novel Word Learning

    Science.gov (United States)

    Lockwood, Gwilym; Dingemanse, Mark; Hagoort, Peter

    2016-01-01

    The existence of sound-symbolism (or a non-arbitrary link between form and meaning) is well-attested. However, sound-symbolism has mostly been investigated with nonwords in forced choice tasks, neither of which are representative of natural language. This study uses ideophones, which are naturally occurring sound-symbolic words that depict sensory…

  18. The Early Years: Becoming Attuned to Sound

    Science.gov (United States)

    Ashbrook, Peggy

    2014-01-01

    Exploration of making and changing sounds is part of the first-grade performance expectation 1-PS4-1, "Plan and conduct investigations to provide evidence that vibrating materials can make sound and that sound can make materials vibrate" (NGSS Lead States 2013, p. 10; see Internet Resource). Early learning experiences build toward…

  19. Bubbles That Change the Speed of Sound

    Science.gov (United States)

    Planinsic, Gorazd; Etkina, Eugenia

    2012-01-01

    The influence of bubbles on sound has long attracted the attention of physicists. In his 1920 book Sir William Bragg described sound absorption caused by foam in a glass of beer tapped by a spoon. Frank S. Crawford described and analyzed the change in the pitch of sound in a similar experiment and named the phenomenon the "hot chocolate effect."…

  20. Lungs and Respiratory System

    Science.gov (United States)

    ... Videos for Educators Search English Español Lungs and Respiratory System KidsHealth / For Parents / Lungs and Respiratory System ... ll have taken at least 600 million breaths. Respiratory System Basics All of this breathing couldn't ...

  1. Childhood Interstitial Lung Disease

    Science.gov (United States)

    ... rule out conditions such as asthma , cystic fibrosis , acid reflux, heart disease, neuromuscular disease, and immune deficiency. Various ... a lung infection. Acid-blocking medicines can prevent acid reflux, which can lead to aspiration. Lung Transplant A ...

  2. Interstitial Lung Disease

    Science.gov (United States)

    ... propranolol (Inderal, Innopran), may harm lung tissue. Some antibiotics. Nitrofurantoin (Macrobid, Macrodantin, others) and ethambutol (Myambutol) can cause lung damage. Anti-inflammatory drugs. Certain anti-inflammatory drugs, such as rituximab ( ...

  3. Eosinophilic Lung Disorders

    Science.gov (United States)

    ... problems characterized by having an increased number of eosinophils (white blood cells) in the lungs. These white ... category of pneumonias that feature increased numbers of eosinophils in the lung tissue. Pneumonia is an inflammatory ...

  4. Lung nodules after whole lung radiation

    International Nuclear Information System (INIS)

    Cohen, M.D.; Mirkin, D.L.; Provisor, A.; Hornback, N.B.; Smith, J.A.; Slabaugh, R.D.

    1983-01-01

    It is essential to recognize radiation pneumonitis after whole lung irradiation, or nodular changes in response to chemotherapy, so that such conditions are not mistaken for tumor metastases, causing grave error in patient management and the possibility of further lung damage

  5. Monotonicity-based electrical impedance tomography for lung imaging

    Science.gov (United States)

    Zhou, Liangdong; Harrach, Bastian; Seo, Jin Keun

    2018-04-01

    This paper presents a monotonicity-based spatiotemporal conductivity imaging method for continuous regional lung monitoring using electrical impedance tomography (EIT). The EIT data (i.e. the boundary current-voltage data) can be decomposed into pulmonary, cardiac and other parts using their different periodic natures. The time-differential current-voltage operator corresponding to the lung ventilation can be viewed as either semi-positive or semi-negative definite owing to monotonic conductivity changes within the lung regions. We used these monotonicity constraints to improve the quality of lung EIT imaging. We tested the proposed methods in numerical simulations, phantom experiments and human experiments.

  6. Sounding rockets explore the ionosphere

    International Nuclear Information System (INIS)

    Mendillo, M.

    1990-01-01

    It is suggested that small, expendable, solid-fuel rockets used to explore ionospheric plasma can offer insight into all the processes and complexities common to space plasma. NASA's sounding rocket program for ionospheric research focuses on the flight of instruments to measure parameters governing the natural state of the ionosphere. Parameters include input functions, such as photons, particles, and composition of the neutral atmosphere; resultant structures, such as electron and ion densities, temperatures and drifts; and emerging signals such as photons and electric and magnetic fields. Systematic study of the aurora is also conducted by these rockets, allowing sampling at relatively high spatial and temporal rates as well as investigation of parameters, such as energetic particle fluxes, not accessible to ground based systems. Recent active experiments in the ionosphere are discussed, and future sounding rocket missions are cited

  7. Sparse representation of Gravitational Sound

    Science.gov (United States)

    Rebollo-Neira, Laura; Plastino, A.

    2018-03-01

    Gravitational Sound clips produced by the Laser Interferometer Gravitational-Wave Observatory (LIGO) and the Massachusetts Institute of Technology (MIT) are considered within the particular context of data reduction. We advance a procedure to this effect and show that these types of signals can be approximated with high quality using significantly fewer elementary components than those required within the standard orthogonal basis framework. Furthermore, a local measure sparsity is shown to render meaningful information about the variation of a signal along time, by generating a set of local sparsity values which is much smaller than the dimension of the signal. This point is further illustrated by recourse to a more complex signal, generated by Milde Science Communication to divulge Gravitational Sound in the form of a ring tone.

  8. Sound Beams with Shockwave Pulses

    Science.gov (United States)

    Enflo, B. O.

    2000-11-01

    The beam equation for a sound beam in a diffusive medium, called the Khokhlov-Zabolotskaya-Kuznetsov (KZK) equation, has a class of solutions, which are power series in the transverse variable with the terms given by a solution of a generalized Burgers’ equation. A free parameter in this generalized Burgers’ equation can be chosen so that the equation describes an N-wave which does not decay. If the beam source has the form of a spherical cap, then a beam with a preserved shock can be prepared. This is done by satisfying an inequality containing the spherical radius, the N-wave pulse duration, the N-wave pulse amplitude, and the sound velocity in the fluid.

  9. The Sound of Being There

    DEFF Research Database (Denmark)

    Nordahl, Rolf; Nilsson, Niels Christian

    2014-01-01

    The concept “presence”—often defined as the sensation of “being there”—has received increasing attention in the last decades. Out of the many domains of application, presence is particularly relevant in relation to Immersive Virtual Reality (IVR). Despite the growing attention in the concept pres...... to illustrating how sound production and perception relate to the four constituents of the framework: immersion, illusions of place, illusions of plausibility, and virtual body ownership....

  10. Propagation of sound in oceans

    Digital Repository Service at National Institute of Oceanography (India)

    Advilkar, P.J.

    prestigious institute. I am privileged to express my sincere thanks to JRF’s Roshin Sir, Bajish Sir, for training me both practically and theoretically about various techniques, without which my work would not have reached its completion. I am equally... wrote his Mathematical Principles of Natural Philosophy which included the first mathematical treatment of sound. The modern study of underwater acoustics can be considered to have started in early 19 th century. In 1826, on Lake Geneva, the speed...

  11. Operator performance and annunciation sounds

    International Nuclear Information System (INIS)

    Patterson, B.K.; Bradley, M.T.; Artiss, W.G.

    1997-01-01

    This paper discusses the audible component of annunciation found in typical operating power stations. The purpose of the audible alarm is stated and the psychological elements involved in the human processing of alarm sounds is explored. Psychological problems with audible annunciation are noted. Simple and more complex improvements to existing systems are described. A modern alarm system is suggested for retrofits or new plant designs. (author)

  12. Numerical value biases sound localization

    OpenAIRE

    Golob, Edward J.; Lewald, Jörg; Getzmann, Stephan; Mock, Jeffrey R.

    2017-01-01

    Speech recognition starts with representations of basic acoustic perceptual features and ends by categorizing the sound based on long-term memory for word meaning. However, little is known about whether the reverse pattern of lexical influences on basic perception can occur. We tested for a lexical influence on auditory spatial perception by having subjects make spatial judgments of number stimuli. Four experiments used pointing or left/right 2-alternative forced choice tasks to examine perce...

  13. Operator performance and annunciation sounds

    Energy Technology Data Exchange (ETDEWEB)

    Patterson, B K; Bradley, M T; Artiss, W G [Human Factors Practical, Dipper Harbour, NB (Canada)

    1998-12-31

    This paper discusses the audible component of annunciation found in typical operating power stations. The purpose of the audible alarm is stated and the psychological elements involved in the human processing of alarm sounds is explored. Psychological problems with audible annunciation are noted. Simple and more complex improvements to existing systems are described. A modern alarm system is suggested for retrofits or new plant designs. (author) 3 refs.

  14. Acoustic analysis of trill sounds.

    Science.gov (United States)

    Dhananjaya, N; Yegnanarayana, B; Bhaskararao, Peri

    2012-04-01

    In this paper, the acoustic-phonetic characteristics of steady apical trills--trill sounds produced by the periodic vibration of the apex of the tongue--are studied. Signal processing methods, namely, zero-frequency filtering and zero-time liftering of speech signals, are used to analyze the excitation source and the resonance characteristics of the vocal tract system, respectively. Although it is natural to expect the effect of trilling on the resonances of the vocal tract system, it is interesting to note that trilling influences the glottal source of excitation as well. The excitation characteristics derived using zero-frequency filtering of speech signals are glottal epochs, strength of impulses at the glottal epochs, and instantaneous fundamental frequency of the glottal vibration. Analysis based on zero-time liftering of speech signals is used to study the dynamic resonance characteristics of vocal tract system during the production of trill sounds. Qualitative analysis of trill sounds in different vowel contexts, and the acoustic cues that may help spotting trills in continuous speech are discussed.

  15. Lung scintigraphy; Centellograma pulmonar

    Energy Technology Data Exchange (ETDEWEB)

    Dalenz, Roberto

    1994-12-31

    A review of lung scintigraphy, perfusion scintigraphy with SPECT, lung ventilation SPECT, blood pool SPECT. The procedure of lung perfusion studies, radiopharmaceutical, administration and clinical applications, imaging processing .Results encountered and evaluation criteria after Biello and Pioped. Recommendations and general considerations have been studied about relation of this radiopharmaceutical with other pathologies.

  16. American Lung Association

    Science.gov (United States)

    ... see if you should get screened. Learn more EDUCATION ADVOCACY RESEARCH Our vision is a world free of lung disease The American Lung Association is ... by lung disease. Help us continue to deliver education, advocacy and research to those who need it. $250 $100 $50 Your best gift Donate now Learn More ... nonprofit software

  17. SARS – Lung Pathology

    Indian Academy of Sciences (India)

    Dry nonproductive cough – may show minimal lung infiltration. Recovery; * Lungs get fluid in bronchi- droplets infective and +ve for virus in culture and PCR. May also have co-infection with chlamydia/metapneumoviruses. Recovery; * Lung tissue destroyed due to ? immunological/cytokine mediated damage-Recovery ...

  18. Analysis and Synthesis of Musical Instrument Sounds

    Science.gov (United States)

    Beauchamp, James W.

    For synthesizing a wide variety of musical sounds, it is important to understand which acoustic properties of musical instrument sounds are related to specific perceptual features. Some properties are obvious: Amplitude and fundamental frequency easily control loudness and pitch. Other perceptual features are related to sound spectra and how they vary with time. For example, tonal "brightness" is strongly connected to the centroid or tilt of a spectrum. "Attack impact" (sometimes called "bite" or "attack sharpness") is strongly connected to spectral features during the first 20-100 ms of sound, as well as the rise time of the sound. Tonal "warmth" is connected to spectral features such as "incoherence" or "inharmonicity."

  19. Underwater Sound Propagation from Marine Pile Driving.

    Science.gov (United States)

    Reyff, James A

    2016-01-01

    Pile driving occurs in a variety of nearshore environments that typically have very shallow-water depths. The propagation of pile-driving sound in water is complex, where sound is directly radiated from the pile as well as through the ground substrate. Piles driven in the ground near water bodies can produce considerable underwater sound energy. This paper presents examples of sound propagation through shallow-water environments. Some of these examples illustrate the substantial variation in sound amplitude over time that can be critical to understand when computing an acoustic-based safety zone for aquatic species.

  20. Material sound source localization through headphones

    Science.gov (United States)

    Dunai, Larisa; Peris-Fajarnes, Guillermo; Lengua, Ismael Lengua; Montaña, Ignacio Tortajada

    2012-09-01

    In the present paper a study of sound localization is carried out, considering two different sounds emitted from different hit materials (wood and bongo) as well as a Delta sound. The motivation of this research is to study how humans localize sounds coming from different materials, with the purpose of a future implementation of the acoustic sounds with better localization features in navigation aid systems or training audio-games suited for blind people. Wood and bongo sounds are recorded after hitting two objects made of these materials. Afterwards, they are analysed and processed. On the other hand, the Delta sound (click) is generated by using the Adobe Audition software, considering a frequency of 44.1 kHz. All sounds are analysed and convolved with previously measured non-individual Head-Related Transfer Functions both for an anechoic environment and for an environment with reverberation. The First Choice method is used in this experiment. Subjects are asked to localize the source position of the sound listened through the headphones, by using a graphic user interface. The analyses of the recorded data reveal that no significant differences are obtained either when considering the nature of the sounds (wood, bongo, Delta) or their environmental context (with or without reverberation). The localization accuracies for the anechoic sounds are: wood 90.19%, bongo 92.96% and Delta sound 89.59%, whereas for the sounds with reverberation the results are: wood 90.59%, bongo 92.63% and Delta sound 90.91%. According to these data, we can conclude that even when considering the reverberation effect, the localization accuracy does not significantly increase.

  1. Sound radiation contrast in MR phase images. Method for the representation of elasticity, sound damping, and sound impedance changes

    International Nuclear Information System (INIS)

    Radicke, Marcus

    2009-01-01

    The method presented in this thesis combines ultrasound techniques with the magnetic-resonance tomography (MRT). An ultrasonic wave generates in absorbing media a static force in sound-propagation direction. The force leads at sound intensities of some W/cm 2 and a sound frequency in the lower MHz range to a tissue shift in the micrometer range. This tissue shift depends on the sound power, the sound frequency, the sound absorption, and the elastic properties of the tissue. A MRT sequence of the Siemens Healthcare AG was modified so that it measures (indirectly) the tissue shift, codes as grey values, and presents as 2D picture. By means of the grey values the sound-beam slope in the tissue can be visualized, and so additionally sound obstacles (changes of the sound impedance) can be detected. By the MRT images token up spatial changes of the tissue parameters sound absorption and elasticity can be detected. In this thesis measurements are presented, which show the feasibility and future chances of this method especially for the mammary-cancer diagnostics. [de

  2. Development and evaluation of in vivo monitoring techniques of high energy radionuclides in the lungs in emergency situations; Desenvolvimento e avaliação de técnicas de monitoração in vivo de radionuclídeos de alta energia nos pulmões em situações de emergência

    Energy Technology Data Exchange (ETDEWEB)

    Mello, J.Q.; Lucena, E.A.; Dantas, A.L.A.; Dantas, B.M., E-mail: jquince@bolsista.ird.gov.br [Instituto de Radioproteção e Dosimetria (IRD/CNEN-RJ), Rio de Janeiro, RJ (Brazil). Divisão de Dosimetria. Laboratório de Monitoração in vivo

    2017-07-01

    Emergency situations in nuclear power plants involving the release of radioactive materials require the use of monitoring techniques for individuals exposed to risks of radionuclide incorporation. Such techniques should provide rapid results and provide sufficient sensitivity for the detection of activities that result in internal doses consistent with exposure limits. A wide variety of radionuclides can be identified and quantified by means of in vivo monitoring techniques in the human body and their availability is of great importance in remediation actions. This work presents the development and validation of an in vivo monitoring method for the evaluation of inhaled radionuclide incorporation. The monitoring system, consisting of an 8 x 4 NaI (Tl) detector installed on the IRD Whole-Body Counter, was calibrated with a chest and lung simulator type LLNL containing {sup 152}Eu. The detection efficiencies corresponding to the most intense photon energies of {sup 152}Eu were calculated and a calibration curve in the range of 100 to 1400 keV was obtained. From this curve, the detection efficiencies, the minimum detectable activities and the detectable minimum effective doses corresponding to the most relevant radionuclides in the case of a radioactive pen-releasing accident were calculated. The technique presents adequate sensitivity for in vivo monitoring in such situations, being able to detect activities that result in effective doses committed below 1 mSv, considering the most probable scenarios of internal exposure.

  3. 67Ga lung scan

    International Nuclear Information System (INIS)

    Niden, A.H.; Mishkin, F.S.; Khurana, M.M.L.; Pick, R.

    1977-01-01

    Twenty-three patients with clinical signs of pulmonary embolic disease and lung infiltrates were studied to determine the value of gallium citrate 67 Ga lung scan in differentiating embolic from inflammatory lung disease. In 11 patients without angiographically proved embolism, only seven had corresponding ventilation-perfusion defects compatible with inflammatory disease. In seven of these 11 patients, the 67 Ga concentration indicated inflammatory disease. In the 12 patients with angiographically proved embolic disease, six had corresponding ventilation-perfusion defects compatible with inflammatory disease. None had an accumulation of 67 Ga in the area of pulmonary infiltrate. Thus, ventilation-perfusion lung scans are of limited value when lung infiltrates are present. In contrast, the accumulation of 67 Ga in the lung indicates an inflammatory process. Gallium imaging can help select those patients with lung infiltrates who need angiography

  4. Sound sensitivity of neurons in rat hippocampus during performance of a sound-guided task

    Science.gov (United States)

    Vinnik, Ekaterina; Honey, Christian; Schnupp, Jan; Diamond, Mathew E.

    2012-01-01

    To investigate how hippocampal neurons encode sound stimuli, and the conjunction of sound stimuli with the animal's position in space, we recorded from neurons in the CA1 region of hippocampus in rats while they performed a sound discrimination task. Four different sounds were used, two associated with water reward on the right side of the animal and the other two with water reward on the left side. This allowed us to separate neuronal activity related to sound identity from activity related to response direction. To test the effect of spatial context on sound coding, we trained rats to carry out the task on two identical testing platforms at different locations in the same room. Twenty-one percent of the recorded neurons exhibited sensitivity to sound identity, as quantified by the difference in firing rate for the two sounds associated with the same response direction. Sensitivity to sound identity was often observed on only one of the two testing platforms, indicating an effect of spatial context on sensory responses. Forty-three percent of the neurons were sensitive to response direction, and the probability that any one neuron was sensitive to response direction was statistically independent from its sensitivity to sound identity. There was no significant coding for sound identity when the rats heard the same sounds outside the behavioral task. These results suggest that CA1 neurons encode sound stimuli, but only when those sounds are associated with actions. PMID:22219030

  5. Lymphocytes on sounding rocket flights.

    Science.gov (United States)

    Cogoli-Greuter, M; Pippia, P; Sciola, L; Cogoli, A

    1994-05-01

    Cell-cell interactions and the formation of cell aggregates are important events in the mitogen-induced lymphocyte activation. The fact that the formation of cell aggregates is only slightly reduced in microgravity suggests that cells are moving and interacting also in space, but direct evidence was still lacking. Here we report on two experiments carried out on a flight of the sounding rocket MAXUS 1B, launched in November 1992 from the base of Esrange in Sweden. The rocket reached the altitude of 716 km and provided 12.5 min of microgravity conditions.

  6. Consort 1 sounding rocket flight

    Science.gov (United States)

    Wessling, Francis C.; Maybee, George W.

    1989-01-01

    This paper describes a payload of six experiments developed for a 7-min microgravity flight aboard a sounding rocket Consort 1, in order to investigate the effects of low gravity on certain material processes. The experiments in question were designed to test the effect of microgravity on the demixing of aqueous polymer two-phase systems, the electrodeposition process, the production of elastomer-modified epoxy resins, the foam formation process and the characteristics of foam, the material dispersion, and metal sintering. The apparatuses designed for these experiments are examined, and the rocket-payload integration and operations are discussed.

  7. The Swedish sounding rocket programme

    International Nuclear Information System (INIS)

    Bostroem, R.

    1980-01-01

    Within the Swedish Sounding Rocket Program the scientific groups perform experimental studies of magnetospheric and ionospheric physics, upper atmosphere physics, astrophysics, and material sciences in zero g. New projects are planned for studies of auroral electrodynamics using high altitude rockets, investigations of noctilucent clouds, and active release experiments. These will require increased technical capabilities with respect to payload design, rocket performance and ground support as compared with the current program. Coordination with EISCAT and the planned Viking satellite is essential for the future projects. (Auth.)

  8. Sound is Multi-Dimensional

    DEFF Research Database (Denmark)

    Bergstrøm-Nielsen, Carl

    2006-01-01

    First part of this work examines the concept of musical parameter theory and discusses its methodical use. Second part is an annotated catalogue of 33 different students' compositions, presented in their totality with English translations, created between 1985 and 2006 as part of the subject...... Intuitive Music at Music Therapy, AAU. 20 of these have sound files as well. The work thus serves as an anthology of this form of composition. All the compositions are systematically presented according to parameters: pitch, duration, dynamics, timbre, density, pulse-no pulse, tempo, stylistic...

  9. Evaluation of multichannel reproduced sound

    DEFF Research Database (Denmark)

    Choisel, Sylvain; Wickelmaier, Florian Maria

    2007-01-01

    A study was conducted with the goal of quantifying auditory attributes which underlie listener preference for multichannel reproduced sound. Short musical excerpts were presented in mono, stereo and several multichannel formats to a panel of forty selected listeners. Scaling of auditory attributes......, as well as overall preference, was based on consistency tests of binary paired-comparison judgments and on modeling the choice frequencies using probabilistic choice models. As a result, the preferences of non-expert listeners could be measured reliably at a ratio scale level. Principal components derived...

  10. Study of the Acoustic Effects of Hydrokinetic Tidal Turbines in Admiralty Inlet, Puget Sound

    Energy Technology Data Exchange (ETDEWEB)

    Brian Polagye; Jim Thomson; Chris Bassett; Jason Wood; Dom Tollit; Robert Cavagnaro; Andrea Copping

    2012-03-30

    Hydrokinetic turbines will be a source of noise in the marine environment - both during operation and during installation/removal. High intensity sound can cause injury or behavioral changes in marine mammals and may also affect fish and invertebrates. These noise effects are, however, highly dependent on the individual marine animals; the intensity, frequency, and duration of the sound; and context in which the sound is received. In other words, production of sound is a necessary, but not sufficient, condition for an environmental impact. At a workshop on the environmental effects of tidal energy development, experts identified sound produced by turbines as an area of potentially significant impact, but also high uncertainty. The overall objectives of this project are to improve our understanding of the potential acoustic effects of tidal turbines by: (1) Characterizing sources of existing underwater noise; (2) Assessing the effectiveness of monitoring technologies to characterize underwater noise and marine mammal responsiveness to noise; (3) Evaluating the sound profile of an operating tidal turbine; and (4) Studying the effect of turbine sound on surrogate species in a laboratory environment. This study focuses on a specific case study for tidal energy development in Admiralty Inlet, Puget Sound, Washington (USA), but the methodologies and results are applicable to other turbine technologies and geographic locations. The project succeeded in achieving the above objectives and, in doing so, substantially contributed to the body of knowledge around the acoustic effects of tidal energy development in several ways: (1) Through collection of data from Admiralty Inlet, established the sources of sound generated by strong currents (mobilizations of sediment and gravel) and determined that low-frequency sound recorded during periods of strong currents is non-propagating pseudo-sound. This helped to advance the debate within the marine and hydrokinetics acoustic

  11. Fungal infections of the lung in children

    Energy Technology Data Exchange (ETDEWEB)

    Toma, Paolo; Colafati, Giovanna Stefania; D' Andrea, Maria Luisa [IRCCS Bambino Gesu Children' s Hospital, Department of Imaging, Rome (Italy); Bertaina, Alice; Mastronuzzi, Angela [IRCCS Bambino Gesu Children' s Hospital, Department of Pediatric Hematology/Oncology and Transfusion Medicine, Rome (Italy); Castagnola, Elio [IRCCS Istituto Giannina Gaslini, Department of Infective Diseases, Genoa (Italy); Finocchi, Andrea [IRCCS Bambino Gesu Children' s Hospital, Department of Pediatrics, Rome (Italy); Lucidi, Vincenzina [IRCCS Bambino Gesu Children' s Hospital, Cystic Fibrosis Center, Rome (Italy); Granata, Claudio [IRCCS Istituto Giannina Gaslini, Department of Pediatric Radiology, Genoa (Italy)

    2016-12-15

    Fungal infections of the lungs are relatively common and potentially life-threatening conditions in immunocompromised children. The role of imaging in children with lung mycosis is to delineate the extension of pulmonary involvement, to assess response to therapy, and to monitor for adverse sequelae such as bronchiectasis and cavitation. The aim of this paper is to show imaging findings in a series of patients with fungal pneumonia from two tertiary children's hospitals, to discuss differential diagnoses and to show how imaging findings can vary depending on the host immune response. (orig.)

  12. Characteristic patterns in the fibrotic lung. Comparing idiopathic pulmonary fibrosis with chronic lung allograft dysfunction.

    Science.gov (United States)

    Fernandez, Isis E; Heinzelmann, Katharina; Verleden, Stijn; Eickelberg, Oliver

    2015-03-01

    Tissue fibrosis, a major cause of death worldwide, leads to significant organ dysfunction in any organ of the human body. In the lung, fibrosis critically impairs gas exchange, tissue oxygenation, and immune function. Idiopathic pulmonary fibrosis (IPF) is the most detrimental and lethal fibrotic disease of the lung, with an estimated median survival of 50% after 3-5 years. Lung transplantation currently remains the only therapeutic alternative for IPF and other end-stage pulmonary disorders. Posttransplant lung function, however, is compromised by short- and long-term complications, most importantly chronic lung allograft dysfunction (CLAD). CLAD affects up to 50% of all transplanted lungs after 5 years, and is characterized by small airway obstruction with pronounced epithelial injury, aberrant wound healing, and subepithelial and interstitial fibrosis. Intriguingly, the mechanisms leading to the fibrotic processes in the engrafted lung exhibit striking similarities to those in IPF; therefore, antifibrotic therapies may contribute to increased graft function and survival in CLAD. In this review, we focus on these common fibrosis-related mechanisms in IPF and CLAD, comparing and contrasting clinical phenotypes, the mechanisms of fibrogenesis, and biomarkers to monitor, predict, or prognosticate disease status.

  13. Numerical value biases sound localization.

    Science.gov (United States)

    Golob, Edward J; Lewald, Jörg; Getzmann, Stephan; Mock, Jeffrey R

    2017-12-08

    Speech recognition starts with representations of basic acoustic perceptual features and ends by categorizing the sound based on long-term memory for word meaning. However, little is known about whether the reverse pattern of lexical influences on basic perception can occur. We tested for a lexical influence on auditory spatial perception by having subjects make spatial judgments of number stimuli. Four experiments used pointing or left/right 2-alternative forced choice tasks to examine perceptual judgments of sound location as a function of digit magnitude (1-9). The main finding was that for stimuli presented near the median plane there was a linear left-to-right bias for localizing smaller-to-larger numbers. At lateral locations there was a central-eccentric location bias in the pointing task, and either a bias restricted to the smaller numbers (left side) or no significant number bias (right side). Prior number location also biased subsequent number judgments towards the opposite side. Findings support a lexical influence on auditory spatial perception, with a linear mapping near midline and more complex relations at lateral locations. Results may reflect coding of dedicated spatial channels, with two representing lateral positions in each hemispace, and the midline area represented by either their overlap or a separate third channel.

  14. Cortical representations of communication sounds.

    Science.gov (United States)

    Heiser, Marc A; Cheung, Steven W

    2008-10-01

    This review summarizes recent research into cortical processing of vocalizations in animals and humans. There has been a resurgent interest in this topic accompanied by an increased number of studies using animal models with complex vocalizations and new methods in human brain imaging. Recent results from such studies are discussed. Experiments have begun to reveal the bilateral cortical fields involved in communication sound processing and the transformations of neural representations that occur among those fields. Advances have also been made in understanding the neuronal basis of interaction between developmental exposures and behavioral experiences with vocalization perception. Exposure to sounds during the developmental period produces large effects on brain responses, as do a variety of specific trained tasks in adults. Studies have also uncovered a neural link between the motor production of vocalizations and the representation of vocalizations in cortex. Parallel experiments in humans and animals are answering important questions about vocalization processing in the central nervous system. This dual approach promises to reveal microscopic, mesoscopic, and macroscopic principles of large-scale dynamic interactions between brain regions that underlie the complex phenomenon of vocalization perception. Such advances will yield a greater understanding of the causes, consequences, and treatment of disorders related to speech processing.

  15. Extreme Energy Events Monitoring report

    CERN Document Server

    Baimukhamedova, Nigina

    2015-01-01

    Following paper reflects the progress I made on Summer Student Program within Extreme Energy Events Monitor project I was working on. During 8 week period I managed to build a simple detector system that is capable of triggering events similar to explosions (sudden change in sound levels) and measuring approximate location of the event. Source codes are available upon request and settings described further.

  16. Evaluative conditioning induces changes in sound valence

    Directory of Open Access Journals (Sweden)

    Anna C. Bolders

    2012-04-01

    Full Text Available Evaluative Conditioning (EC has hardly been tested in the auditory domain, but it is a potentially valuable research tool. In Experiment 1 we investigated whether the affective evaluation of short environmental sounds can be changed using affective words as unconditioned stimuli (US. Congruence effects on an affective priming task (APT for conditioned sounds demonstrated successful EC. Subjective ratings for sounds paired with negative words changed accordingly. In Experiment 2 we investigated whether the acquired valence remains stable after repeated presentation of the conditioned sound without the US or whether extinction occurs. The acquired affective value remained present, albeit weaker, even after 40 extinction trials. These results warrant the use of EC to study processing of short environmental sounds with acquired valence, even if this requires repeated stimulus presentations. This paves the way for studying processing of affective environmental sounds while effectively controlling low level-stimulus properties.

  17. Electromagnetic sounding of the Earth's interior

    CERN Document Server

    Spichak, Viacheslav V

    2015-01-01

    Electromagnetic Sounding of the Earth's Interior 2nd edition provides a comprehensive up-to-date collection of contributions, covering methodological, computational and practical aspects of Electromagnetic sounding of the Earth by different techniques at global, regional and local scales. Moreover, it contains new developments such as the concept of self-consistent tasks of geophysics and , 3-D interpretation of the TEM sounding which, so far, have not all been covered by one book. Electromagnetic Sounding of the Earth's Interior 2nd edition consists of three parts: I- EM sounding methods, II- Forward modelling and inversion techniques, and III - Data processing, analysis, modelling and interpretation. The new edition includes brand new chapters on Pulse and frequency electromagnetic sounding for hydrocarbon offshore exploration. Additionally all other chapters have been extensively updated to include new developments. Presents recently developed methodological findings of the earth's study, including seism...

  18. Neuroanatomic organization of sound memory in humans.

    Science.gov (United States)

    Kraut, Michael A; Pitcock, Jeffery A; Calhoun, Vince; Li, Juan; Freeman, Thomas; Hart, John

    2006-11-01

    The neural interface between sensory perception and memory is a central issue in neuroscience, particularly initial memory organization following perceptual analyses. We used functional magnetic resonance imaging to identify anatomic regions extracting initial auditory semantic memory information related to environmental sounds. Two distinct anatomic foci were detected in the right superior temporal gyrus when subjects identified sounds representing either animals or threatening items. Threatening animal stimuli elicited signal changes in both foci, suggesting a distributed neural representation. Our results demonstrate both category- and feature-specific responses to nonverbal sounds in early stages of extracting semantic memory information from these sounds. This organization allows for these category-feature detection nodes to extract early, semantic memory information for efficient processing of transient sound stimuli. Neural regions selective for threatening sounds are similar to those of nonhuman primates, demonstrating semantic memory organization for basic biological/survival primitives are present across species.

  19. Musical Sounds, Motor Resonance, and Detectable Agency

    Directory of Open Access Journals (Sweden)

    Jacques Launay

    2015-09-01

    Full Text Available This paper discusses the paradox that while human music making evolved and spread in an environment where it could only occur in groups, it is now often apparently an enjoyable asocial phenomenon. Here I argue that music is, by definition, sound that we believe has been in some way organized by a human agent, meaning that listening to any musical sounds can be a social experience. There are a number of distinct mechanisms by which we might associate musical sound with agency. While some of these mechanisms involve learning motor associations with that sound, it is also possible to have a more direct relationship from musical sound to agency, and the relative importance of these potentially independent mechanisms should be further explored. Overall, I conclude that the apparent paradox of solipsistic musical engagement is in fact unproblematic, because the way that we perceive and experience musical sounds is inherently social.

  20. First and second sound in He films

    International Nuclear Information System (INIS)

    Oh, H.G.; Um, C.I.; Kahng, W.H.; Isihara, A.

    1986-01-01

    In consideration of a collision integral in the Boltzmann equation and with use of kinetic and hydrodynamical equations, the velocities of the first and second sound in liquid 4 He films are evaluated as functions of temperature, and the attenuation coefficients are obtained. The second sound is 2/sup -1/2/ times the first-sound velocity in the low-temperature and low-frequency limit

  1. Visualizing Sound Directivity via Smartphone Sensors

    OpenAIRE

    Hawley, Scott H.; McClain Jr, Robert E.

    2017-01-01

    We present a fast, simple method for automated data acquisition and visualization of sound directivity, made convenient and accessible via a smartphone app, "Polar Pattern Plotter." The app synchronizes measurements of sound volume with the phone's angular orientation obtained from either compass, gyroscope or accelerometer sensors and produces a graph and exportable data file. It is generalizable to various sound sources and receivers via the use of an input-jack-adaptor to supplant the smar...

  2. Improving Sound Systems by Electrical Means

    OpenAIRE

    Schneider, Henrik; Andersen, Michael A. E.; Knott, Arnold

    2015-01-01

    The availability and flexibility of audio services on various digital platforms have created a high demand for a large range of sound systems. The fundamental components of sound systems such as docking stations, sound bars and wireless mobile speakers consists of a power supply, amplifiers and transducers. Due to historical reasons the design of each of these components are commonly handled separately which are indeed limiting the full performance potential of such systems. To state some exa...

  3. Lung cancer in elderly

    International Nuclear Information System (INIS)

    Wagnerova, M.

    2007-01-01

    Lung cancer is the leading cause of cancer deaths in Europe and USA. The median age of diagnosis is currently 69 years, however this is gradually increasing with the aging population. Patients over age of 70 represent 40 % of all patients with non-small cell lung cancer. Age alone has not been found to be a significant prognostic factor in many malignancies, including lung cancer with performance status and stage being of greater importance. In lung cancer it is also evident that older patients gain equivalent benefit from cancer therapies as their younger counterparts. Elderly patients are under-treated in all aspects of their disease course from histological diagnosis to active therapy with surgical resection, radiotherapy or chemotherapy, irrespective of performance status or co-morbidities. Elderly patients are also underrepresented in lung cancer clinical trials. In this review is presented knowledge about lung cancer in elderly. (author)

  4. Diet and lung cancer

    DEFF Research Database (Denmark)

    Fabricius, P; Lange, Peter

    2003-01-01

    Lung cancer is the leading cause of cancer-related deaths worldwide. While cigarette smoking is of key importance, factors such as diet also play a role in the development of lung cancer. MedLine and Embase were searched with diet and lung cancer as the key words. Recently published reviews...... and large well designed original articles were preferred to form the basis for the present article. A diet rich in fruit and vegetables reduces the incidence of lung cancer by approximately 25%. The reduction is of the same magnitude in current smokers, ex-smokers and never smokers. Supplementation...... with vitamins A, C and E and beta-carotene offers no protection against the development of lung cancer. On the contrary, beta-carotene supplementation has, in two major randomised intervention trials, resulted in an increased mortality. Smoking remains the leading cause of lung cancer. The adverse effects...

  5. Residential ozone and lung function in the elderly

    DEFF Research Database (Denmark)

    Braeuner, Elvira V.; Karottki, Dorina Gabriela; Frederiksen, Marie

    2016-01-01

    elderly non-smokers. Indoor ozone was measured passively in homes, while urban background outdoor ozone was monitored continuously at a fixed monitoring station located on the roof of the 20-m high university H.C. Ørsteds campus building in a park area. Lung function was measured at baseline as well...

  6. Vocal Noise Cancellation From Respiratory Sounds

    National Research Council Canada - National Science Library

    Moussavi, Zahra

    2001-01-01

    Although background noise cancellation for speech or electrocardiographic recording is well established, however when the background noise contains vocal noises and the main signal is a breath sound...

  7. Velocity of sound measurements in gaseous per-fluorocarbons and their custom mixtures

    CERN Document Server

    Vacek, V; Lindsay, S

    2000-01-01

    An inexpensive sonar instrument was prepared for measurements of sound velocity in two fluorocarbon vapors; per-fluoro-n-propane (C3F8), per-fluoro-n-butane (C4F10), and their custom mixtures. The apparatus, measurement principle and instrument software are described. All sound velocity measurements in per-fluorocarbons were made in the low pressure range between 0.01 and 0.4 MPa, and at temperatures between 253 and 303 K. The purity of the C3F8 and C4F10 samples was checked using gas chromatography. Uncertainties in the speed of sound measurements were better than ± 0.1 %. Comparisons were made with theoretical predictions of sound velocity for the two individual components. The instrument was then used for concentration monitoring of custom C3F8/C4F10 mixtures.

  8. Acoustic phenomena observed in lung auscultation

    Science.gov (United States)

    Korenbaum, V. I.; Tagil'Tsev, A. A.; Kulakov, Yu. V.

    2003-05-01

    The results of studying respiratory noise at the chest wall by the method of acoustic intensimetry reveal the presence of frequency components with different signs of the real and imaginary parts of the cross spectrum obtained for the responses of the receivers of vibratory displacement and dynamic force. An acoustic model is proposed to explain this difference on the basis of the hypothesis that the contributions of both air-borne and structure-borne sound are significant in the transmission of respiratory noise to the chest wall. It is shown that, when considered as an acoustic channel for the basic respiratory noise, the respiratory system of an adult subject has two resonances: in the frequency bands within 110 150 and 215 350 Hz. For adults in normal condition, the air-borne component of the basic respiratory noise predominates in the region 100 300 Hz in the lower parts of lungs. At forced respiration of healthy adults, the sounds of vesicular respiration are generated by the turbulent air flow in the 11th-through 13th-generation bronchi, and the transmission of these sounds to the chest wall in normal condition is mainly through air and is determined by the resonance of the vibratory system formed by the elasticity of air in the respiratory ducts of lungs and by the surface mass density of the chest wall. It is demonstrated that the distance from the chest wall to the sources of structure-borne additional respiratory noise, namely, wheezing with frequencies above 300 Hz, can be estimated numerically from the ratio between the real and imaginary parts of the cross spectrum on the assumption that the source is of the quadrupole type.

  9. Epidemiology of Lung Cancer.

    Science.gov (United States)

    Schwartz, Ann G; Cote, Michele L

    2016-01-01

    Lung cancer continues to be one of the most common causes of cancer death despite understanding the major cause of the disease: cigarette smoking. Smoking increases lung cancer risk 5- to 10-fold with a clear dose-response relationship. Exposure to environmental tobacco smoke among nonsmokers increases lung cancer risk about 20%. Risks for marijuana and hookah use, and the new e-cigarettes, are yet to be consistently defined and will be important areas for continued research as use of these products increases. Other known environmental risk factors include exposures to radon, asbestos, diesel, and ionizing radiation. Host factors have also been associated with lung cancer risk, including family history of lung cancer, history of chronic obstructive pulmonary disease and infections. Studies to identify genes associated with lung cancer susceptibility have consistently identified chromosomal regions on 15q25, 6p21 and 5p15 associated with lung cancer risk. Risk prediction models for lung cancer typically include age, sex, cigarette smoking intensity and/or duration, medical history, and occupational exposures, however there is not yet a risk prediction model currently recommended for general use. As lung cancer screening becomes more widespread, a validated model will be needed to better define risk groups to inform screening guidelines.

  10. Nonrespiratory lung function

    International Nuclear Information System (INIS)

    Isawa, Toyoharu

    1994-01-01

    The function of the lungs is primarily the function as a gas exchanger: the venous blood returning to the lungs is arterialized with oxygen in the lungs and the arterialized blood is sent back again to the peripheral tissues of the whole body to be utilized for metabolic oxygenation. Besides the gas exchanging function which we call ''respiratory lung function'' the lungs have functions that have little to do with gas exchange itself. We categorically call the latter function of the lungs as ''nonrespiratory lung function''. The lungs consist of the conductive airways, the gas exchanging units like the alveoli, and the interstitial space that surrounds the former two compartments. The interstitial space contains the blood and lymphatic capillaries, collagen and elastic fibers and cement substances. The conductive airways and the gas exchanging units are directly exposed to the atmosphere that contains various toxic and nontoxic gases, fume and biological or nonbiological particles. Because the conductive airways are equipped with defense mechanisms like mucociliary clearance or coughs to get rid of these toxic gases, particles or locally produced biological debris, we are usually free from being succumbed to ill effects of inhaled materials. By use of nuclear medicine techniques, we can now evaluate mucociliary clearance function, and other nonrespiratory lung functions as well in vivo

  11. Cervical lung hernia

    Science.gov (United States)

    Lightwood, Robin G.; Cleland, W. P.

    1974-01-01

    Lightwood, R. G., and Cleland, W. P. (1974).Thorax, 29, 349-351. Cervical lung hernia. Lung hernias occur in the cervical position in about one third of cases. The remainder appear through the chest wall. Some lung hernias are congenital, but trauma is the most common cause. The indications for surgery depend upon the severity of symptoms. Repair by direct suture can be used for small tears in Sibson's (costovertebral) fascia while larger defects have been closed using prosthetic materials. Four patients with cervical lung hernia are described together with an account of their operations. PMID:4850946

  12. Nonrespiratory lung function

    Energy Technology Data Exchange (ETDEWEB)

    Isawa, Toyoharu [Tohoku University Research Institute for Chest Disease and Cancer, Sendai (Japan)

    1994-07-01

    The function of the lungs is primarily the function as a gas exchanger: the venous blood returning to the lungs is arterialized with oxygen in the lungs and the arterialized blood is sent back again to the peripheral tissues of the whole body to be utilized for metabolic oxygenation. Besides the gas exchanging function which we call ''respiratory lung function'' the lungs have functions that have little to do with gas exchange itself. We categorically call the latter function of the lungs as ''nonrespiratory lung function''. The lungs consist of the conductive airways, the gas exchanging units like the alveoli, and the interstitial space that surrounds the former two compartments. The interstitial space contains the blood and lymphatic capillaries, collagen and elastic fibers and cement substances. The conductive airways and the gas exchanging units are directly exposed to the atmosphere that contains various toxic and nontoxic gases, fume and biological or nonbiological particles. Because the conductive airways are equipped with defense mechanisms like mucociliary clearance or coughs to get rid of these toxic gases, particles or locally produced biological debris, we are usually free from being succumbed to ill effects of inhaled materials. By use of nuclear medicine techniques, we can now evaluate mucociliary clearance function, and other nonrespiratory lung functions as well in vivo.

  13. Parasitic diseases of lungs

    International Nuclear Information System (INIS)

    Rozenshtraukh, L.C.; Rybakova, N.I.; Vinner, M.G.

    1987-01-01

    Roentgenologic semiotics of the main parasitic diseases of lungs is described: echinococcosis, paragonimiasis, cysticercosis, toxoplasmosis, ascariasis, amebiosis and some rarely met parasitic diseases

  14. Making fictions sound real - On film sound, perceptual realism and genre

    Directory of Open Access Journals (Sweden)

    Birger Langkjær

    2010-05-01

    Full Text Available This article examines the role that sound plays in making fictions perceptually real to film audiences, whether these fictions are realist or non-realist in content and narrative form. I will argue that some aspects of film sound practices and the kind of experiences they trigger are related to basic rules of human perception, whereas others are more properly explained in relation to how aesthetic devices, including sound, are used to characterise the fiction and thereby make it perceptually real to its audience. Finally, I will argue that not all genres can be defined by a simple taxonomy of sounds. Apart from an account of the kinds of sounds that typically appear in a specific genre, a genre analysis of sound may also benefit from a functionalist approach that focuses on how sounds can make both realist and non-realist aspects of genres sound real to audiences.

  15. Making fictions sound real - On film sound, perceptual realism and genre

    Directory of Open Access Journals (Sweden)

    Birger Langkjær

    2009-09-01

    Full Text Available This article examines the role that sound plays in making fictions perceptually real to film audiences, whether these fictions are realist or non-realist in content and narrative form. I will argue that some aspects of film sound practices and the kind of experiences they trigger are related to basic rules of human perception, whereas others are more properly explained in relation to how aesthetic devices, including sound, are used to characterise the fiction and thereby make it perceptually real to its audience. Finally, I will argue that not all genres can be defined by a simple taxonomy of sounds. Apart from an account of the kinds of sounds that typically appear in a specific genre, a genre analysis of sound may also benefit from a functionalist approach that focuses on how sounds can make both realist and non-realist aspects of genres sound real to audiences.

  16. Sound specificity effects in spoken word recognition: The effect of integrality between words and sounds

    DEFF Research Database (Denmark)

    Strori, Dorina; Zaar, Johannes; Cooke, Martin

    2017-01-01

    Recent evidence has shown that nonlinguistic sounds co-occurring with spoken words may be retained in memory and affect later retrieval of the words. This sound-specificity effect shares many characteristics with the classic voice-specificity effect. In this study, we argue that the sound......-specificity effect is conditional upon the context in which the word and sound coexist. Specifically, we argue that, besides co-occurrence, integrality between words and sounds is a crucial factor in the emergence of the effect. In two recognition-memory experiments, we compared the emergence of voice and sound...... from a mere co-occurrence context effect by removing the intensity modulation. The absence of integrality led to the disappearance of the sound-specificity effect. Taken together, the results suggest that the assimilation of background sounds into memory cannot be reduced to a simple context effect...

  17. A noise reduction technique based on nonlinear kernel function for heart sound analysis.

    Science.gov (United States)

    Mondal, Ashok; Saxena, Ishan; Tang, Hong; Banerjee, Poulami

    2017-02-13

    The main difficulty encountered in interpretation of cardiac sound is interference of noise. The contaminated noise obscures the relevant information which are useful for recognition of heart diseases. The unwanted signals are produced mainly by lungs and surrounding environment. In this paper, a novel heart sound de-noising technique has been introduced based on a combined framework of wavelet packet transform (WPT) and singular value decomposition (SVD). The most informative node of wavelet tree is selected on the criteria of mutual information measurement. Next, the coefficient corresponding to the selected node is processed by SVD technique to suppress noisy component from heart sound signal. To justify the efficacy of the proposed technique, several experiments have been conducted with heart sound dataset, including normal and pathological cases at different signal to noise ratios. The significance of the method is validated by statistical analysis of the results. The biological information preserved in de-noised heart sound (HS) signal is evaluated by k-means clustering algorithm and Fit Factor calculation. The overall results show that proposed method is superior than the baseline methods.

  18. Results of time-domain electromagnetic soundings in Miami-Dade and southern Broward Counties, Florida

    Science.gov (United States)

    Fitterman, David V.; Prinos, Scott T.

    2011-01-01

    Time-domain electromagnetic (TEM) soundings were made in Miami-Dade and southern Broward Counties to aid in mapping the landward extent of saltwater in the Biscayne aquifer. A total of 79 soundings were collected in settings ranging from urban to undeveloped land, with some of the former posing problems of land access and interference from anthropogenic features. TEM soundings combined with monitoring-well data were used to determine if the saltwater front had moved since the last time it was mapped, to provide additional spatial coverage where existing monitoring wells were insufficient, and to help interpret a previously collected helicopter electromagnetic (HEM) survey flown in the southernmost portion of the study area. TEM soundings were interpreted as layered resistivity-depth models. Using information from well logs and water-quality data, the resistivity of the freshwater saturated Biscayne aquifer is expected to be above 30 ohm-meters, and the saltwater-saturated aquifer will have resistivities of less than 10 ohm-meters allowing determination of water quality from the TEM interpretations. TEM models from 29 soundings were compared to electromagnetic induction logs collected in nearby monitoring wells. In general, the agreement of these results was very good, giving confidence in the use of the TEM data for mapping saltwater encroachment.

  19. Dutch Lung Surgery Audit: A National Audit Comprising Lung and Thoracic Surgery Patients.

    Science.gov (United States)

    Berge, Martijn Ten; Beck, Naomi; Heineman, David Jonathan; Damhuis, Ronald; Steup, Willem Hans; van Huijstee, Pieter Jan; Eerenberg, Jan Peter; Veen, Eelco; Maat, Alexander; Versteegh, Michel; van Brakel, Thomas; Schreurs, Wilhemina Hendrika; Wouters, Michel Wilhelmus

    2018-04-21

    The nationwide Dutch Lung Surgery Audit (DLSA) started in 2012 to monitor and evaluate the quality of lung surgery in the Netherlands as an improvement tool. This outline describes the establishment, structure and organization of the audit by the Dutch Society of Lung Surgeons (NVvL) and the Dutch Society of Cardiothoracic Surgeons (NVT), in collaboration with the Dutch Institute for Clinical Auditing (DICA). In addition, first four-year results are presented. The NVvL and NVT initiated a web-based registration including weekly updated online feedback for participating hospitals. Data verification by external data managers is performed on regular basis. The audit is incorporated in national quality improvement programs and participation in the DLSA is mandatory by health insurance organizations and the National Healthcare Inspectorate. Between 1 January 2012 and 31 December 2015, all hospitals performing lung surgery participated and a total of 19,557 patients were registered from which almost half comprised lung cancer patients. Nationwide the guideline adherence increased over the years and 96.5% of lung cancer patients were discussed in preoperative multidisciplinary teams. Overall postoperative complications and mortality after non-small cell lung cancer surgery were 15.5% and 2.0%, respectively. The audit provides reliable benchmarked information for caregivers and hospital management with potential to start local, regional or national improvement initiatives. Currently, the audit is further completed with data from non-surgical lung cancer patients including treatment data from pulmonary oncologists and radiation oncologists. This will ultimately provide a comprehensive overview of lung cancer treatment in The Netherlands. Copyright © 2018. Published by Elsevier Inc.

  20. Can road traffic mask sound from wind turbines? Response to wind turbine sound at different levels of road traffic sound

    International Nuclear Information System (INIS)

    Pedersen, Eja; Berg, Frits van den; Bakker, Roel; Bouma, Jelte

    2010-01-01

    Wind turbines are favoured in the switch-over to renewable energy. Suitable sites for further developments could be difficult to find as the sound emitted from the rotor blades calls for a sufficient distance to residents to avoid negative effects. The aim of this study was to explore if road traffic sound could mask wind turbine sound or, in contrast, increases annoyance due to wind turbine noise. Annoyance of road traffic and wind turbine noise was measured in the WINDFARMperception survey in the Netherlands in 2007 (n=725) and related to calculated levels of sound. The presence of road traffic sound did not in general decrease annoyance with wind turbine noise, except when levels of wind turbine sound were moderate (35-40 dB(A) Lden) and road traffic sound level exceeded that level with at least 20 dB(A). Annoyance with both noises was intercorrelated but this correlation was probably due to the influence of individual factors. Furthermore, visibility and attitude towards wind turbines were significantly related to noise annoyance of modern wind turbines. The results can be used for the selection of suitable sites, possibly favouring already noise exposed areas if wind turbine sound levels are sufficiently low.