Comparison of clinical outcomes between luminal invasive ductal carcinoma and luminal invasive lobular carcinoma

International Nuclear Information System (INIS)

Adachi, Yayoi; Ishiguro, Junko; Kotani, Haruru; Hisada, Tomoka; Ichikawa, Mari; Gondo, Naomi; Yoshimura, Akiyo; Kondo, Naoto; Hattori, Masaya; Sawaki, Masataka; Fujita, Takashi; Kikumori, Toyone; Yatabe, Yasushi; Kodera, Yasuhiro; Iwata, Hiroji

2016-01-01

The pathological and clinical features of invasive lobular carcinoma (ILC) differ from those of invasive ductal carcinoma (IDC). Several studies have indicated that patients with ILC have a better prognosis than those with ductal carcinoma. However, no previous study has considered the molecular subtypes and histological subtypes of ILC. We compared prognosis between IDC and classical, luminal type ILC and developed prognostic factors for early breast cancer patients with classical luminal ILC. Four thousand one hundred ten breast cancer patients were treated at the Aichi Cancer Center Hospital from 2003 to 2012. We identified 1,661 cases with luminal IDC and 105 cases with luminal classical ILC. We examined baseline characteristics, clinical outcomes, and prognostic factors of luminal ILC. The prognosis of luminal ILC was significantly worse than that of luminal IDC. The rates of 5-year disease free survival (DFS) were 91.9 % and 88.4 % for patients with luminal IDC and luminal ILC, respectively (P = 0.008). The rates of 5-year overall survival (OS) were 97.6 % and 93.1 % for patients with luminal IDC and luminal ILC respectively (P = 0.030). Although we analyzed prognosis according to stratification by tumor size, luminal ILC tended to have worse DFS than luminal IDC in the large tumor group. In addition, although our analysis was performed according to matching lymph node status, luminal ILC had a significantly worse DFS and OS than luminal IDC in node-positive patients. Survival curves showed that the prognosis for ILC became worse than IDC over time. Multivariate analysis showed that ILC was an important factor related to higher risk of recurrence of luminal type breast cancer, even when tumor size, lymph node status and histological grade were considered. Luminal ILC had worse outcomes than luminal IDC. Consequently, different treatment approaches should be used for luminal ILC than for luminal IDC. The online version of this article (doi:10.1186/s12885

Global Infrared–Radio Spectral Energy Distributions of Galactic Massive Star-Forming Regions

Science.gov (United States)

Povich, Matthew Samuel; Binder, Breanna Arlene

2018-01-01

We present a multiwavelength study of 30 Galactic massive star-forming regions. We fit multicomponent dust, blackbody, and power-law continuum models to 3.6 µm through 10 mm spectral energy distributions obtained from Spitzer, MSX, IRAS, Herschel, and Planck archival survey data. Averaged across our sample, ~20% of Lyman continuum photons emitted by massive stars are absorbed by dust before contributing to the ionization of H II regions, while ~50% of the stellar bolometric luminosity is absorbed and reprocessed by dust in the H II regions and surrounding photodissociation regions. The most luminous, infrared-bright regions that fully sample the upper stellar initial mass function (ionizing photon rates NC ≥ 1050 s–1 and total infrared luminosity LTIR ≥ 106.8 L⊙) have higher percentages of absorbed Lyman continuum photons (~40%) and dust-reprocessed starlight (~80%). The monochromatic 70-µm luminosity L70 is linearly correlated with LTIR, and on average L70/LTIR = 50%, in good agreement with extragalactic studies. Calibrated against the known massive stellar content in our sampled H II regions, we find that star formation rates based on L70 are in reasonably good agreement with extragalactic calibrations, when corrected for the smaller physical sizes of the Galactic regions. We caution that absorption of Lyman continuum photons prior to contributing to the observed ionizing photon rate may reduce the attenuation-corrected Hα emission, systematically biasing extragalactic calibrations toward lower star formation rates when applied to spatially-resolved studies of obscured star formation.This work was supported by the National Science Foundation under award CAREER-1454333.

Luminous quasars do not live in the most overdense regions of galaxies at z ˜ 4

Science.gov (United States)

Uchiyama, Hisakazu; Toshikawa, Jun; Kashikawa, Nobunari; Overzier, Roderik; Chiang, Yi-Kuan; Marinello, Murilo; Tanaka, Masayuki; Niino, Yuu; Ishikawa, Shogo; Onoue, Masafusa; Ichikawa, Kohei; Akiyama, Masayuki; Coupon, Jean; Harikane, Yuichi; Imanishi, Masatoshi; Kodama, Tadayuki; Komiyama, Yutaka; Lee, Chien-Hsiu; Lin, Yen-Ting; Miyazaki, Satoshi; Nagao, Tohru; Nishizawa, Atsushi J.; Ono, Yoshiaki; Ouchi, Masami; Wang, Shiang-Yu

2018-01-01

We present the cross-correlation between 151 luminous quasars (MUV 4 σ. The distributions of the distances between quasars and the nearest protoclusters and the significance of the overdensity at the positions of quasars are statistically identical to those found for g-dropout galaxies, suggesting that quasars tend to reside in almost the same environment as star-forming galaxies at this redshift. Using stacking analysis, we find that the average density of g-dropout galaxies around quasars is slightly higher than that around g-dropout galaxies on 1.0-2.5 pMpc scales, while at anti-correlated with overdensity. These findings are consistent with a scenario in which luminous quasars at z ˜ 4 reside in structures that are less massive than those expected for the progenitors of today's rich clusters of galaxies, and possibly that luminous quasars may be suppressing star formation in their close vicinity.

Luminous Infrared Galaxies. III. Multiple Merger, Extended Massive Star Formation, Galactic Wind, and Nuclear Inflow in NGC 3256

Science.gov (United States)

Lípari, S.; Díaz, R.; Taniguchi, Y.; Terlevich, R.; Dottori, H.; Carranza, G.

2000-08-01

We report detailed evidence for multiple merger, extended massive star formation, galactic wind, and circular/noncircular motions in the luminous infrared galaxy NGC 3256, based on observations of high-resolution imaging (Hubble Space Telescope, ESO NTT), and extensive spectroscopic data (more than 1000 spectra, collected at Estación Astrofísica de Bosque Alegre, Complejo Astronómico el Leoncito, Cerro Tololo InterAmerican Observatory, and IUE observatories). We find in a detailed morphological study (resolution ~15 pc) that the extended massive star formation process detected previously in NGC 3256 shows extended triple asymmetrical spiral arms (r~5 kpc), emanating from three different nuclei. The main optical nucleus shows a small spiral disk (r~500 pc), which is a continuation of the external one and reaches the very nucleus. The core shows blue elongated structure (50 pc×25 pc) and harbors a blue stellar cluster candidate (r~8 pc). We discuss this complex morphology in the framework of an extended massive star formation driven by a multiple merger process (models of Hernquist et al. and Taniguchi et al.). We study the kinematics of this system and present a detailed Hα velocity field for the central region (40''×40'' rmax~30''~5 kpc), with a spatial resolution of 1" and errors of +/-15 km s-1. The color and isovelocity maps show mainly (1) a kinematic center of circular motion with ``spider'' shape, located between the main optical nucleus and the close (5") mid-IR nucleus and (2) noncircular motions in the external parts. We obtained three ``sinusoidal rotation curves'' (from the Hα velocity field) around position angle (P.A.) ~55°, ~90°, and ~130°. In the main optical nucleus we found a clear ``outflow component'' associated with galactic winds plus an ``inflow radial motion.'' The outflow component was also detected in the central and external regions (rstandard models of photoionization, shocks, and starbursts). We present four detailed emission

Research on the calibration methods of the luminance parameter of radiation luminance meters

Science.gov (United States)

Cheng, Weihai; Huang, Biyong; Lin, Fangsheng; Li, Tiecheng; Yin, Dejin; Lai, Lei

2017-10-01

This paper introduces standard diffusion reflection white plate method and integrating sphere standard luminance source method to calibrate the luminance parameter. The paper compares the effects of calibration results by using these two methods through principle analysis and experimental verification. After using two methods to calibrate the same radiation luminance meter, the data obtained verifies the testing results of the two methods are both reliable. The results show that the display value using standard white plate method has fewer errors and better reproducibility. However, standard luminance source method is more convenient and suitable for on-site calibration. Moreover, standard luminance source method has wider range and can test the linear performance of the instruments.

New Galactic Candidate Luminous Blue Variables and Wolf-Rayet Stars

Science.gov (United States)

Stringfellow, Guy S.; Gvaramadze, Vasilii V.; Beletsky, Yuri; Kniazev, Alexei Y.

2012-04-01

We have undertaken a near-infrared spectral survey of stars associated with compact mid-IR shells recently revealed by the MIPSGAL (24 μm) and GLIMPSE (8 μm) Spitzer surveys, whose morphologies are typical of circumstellar shells produced by massive evolved stars. Through spectral similarity with known Luminous Blue Variable (LBV) and Wolf-Rayet (WR) stars, a large population of candidate LBVs (cLBVs) and a smaller number of new WR stars are being discovered. This significantly increases the Galactic cLBV population and confirms that nebulae are inherent to most (if not all) objects of this class.

Properties of hot luminous stars; Proceedings of the First Boulder-Munich Workshop, Boulder, CO, Aug. 6-11, 1988

International Nuclear Information System (INIS)

Garmany, C.D.

1990-01-01

Various papers on the properties of hot luminous stars are presented. Individual topics addressed include: problems in photometry of early-type stars; digital optical morphology of OB spectra; massive-star content of the Magellanic Clouds; observations of massive OB stars; LSS 3074, a new double-lined early O-type binary; non-LTE line blanketing with elements 1-28; non-LTE analysis of four PG1159 stars; rescaling method for model atmospheres of hot stars; stellar wind albedo effects on hot photospheres; atomic data and models for hot star abundance determinations; ring nebulae analysis as a probe for WR atmospheres; coordinated observations of P Cygni; radiation-driven winds of hot luminous stars; winds of O stars: velocities and ionization; methods of radiative transfer in expanding atmospheres; mass loss from extragalactic O stars; H-alpha observations of O- and B-type stars; applicability of steady models for hot-star winds; mass of the O6Iaf star HD 153919; stellar winds in Beta Lyrae; models of WR stars; observational abundances of WR stars, the all-variable WC7 binary HD193793

A SPECTROSCOPIC SURVEY OF MASSIVE STARS IN M31 AND M33

Energy Technology Data Exchange (ETDEWEB)

Massey, Philip; Neugent, Kathryn F.; Smart, Brianna M., E-mail: phil.massey@lowell.edu, E-mail: kneugent@lowell.edu, E-mail: bsmart@astro.wisc.edu [Lowell Observatory, 1400 W Mars Hill Road, Flagstaff, AZ 86001 (United States)

2016-09-01

We describe our spectroscopic follow-up to the Local Group Galaxy Survey (LGGS) photometry of M31 and M33. We have obtained new spectroscopy of 1895 stars, allowing us to classify 1496 of them for the first time. Our study has identified many foreground stars, and established membership for hundreds of early- and mid-type supergiants. We have also found nine new candidate luminous blue variables and a previously unrecognized Wolf–Rayet star. We republish the LGGS M31 and M33 catalogs with improved coordinates, and including spectroscopy from the literature and our new results. The spectroscopy in this paper is responsible for the vast majority of the stellar classifications in these two nearby spiral neighbors. The most luminous (and hence massive) of the stars in our sample are early-type B supergiants, as expected; the more massive O stars are more rare and fainter visually, and thus mostly remain unobserved so far. The majority of the unevolved stars in our sample are in the 20–40 M {sub ⊙} range.

RESOLVING THE CIRCUMSTELLAR DISK AROUND THE MASSIVE PROTOSTAR DRIVING THE HH 80-81 JET

Energy Technology Data Exchange (ETDEWEB)

Carrasco-Gonzalez, Carlos [Max-Planck-Institut fuer Radioastronomie (MPIfR), Auf dem Huegel 69, 53121 Bonn (Germany); Galvan-Madrid, Roberto [European Southern Observatory, Karl-Schwarzschild-Str. 2, 85748 Garching (Germany); Anglada, Guillem; Osorio, Mayra [Instituto de Astrofisica de Andalucia, CSIC, Camino Bajo de Huetor 50, E-18008 Granada (Spain); D' Alessio, Paola; Rodriguez, Luis F. [Centro de Radioastronomia y Astrofisica UNAM, Apartado Postal 3-72 (Xangari), 58089 Morelia, Michoacan (Mexico); Hofner, Peter [Physics Department, New Mexico Tech, 801 Leroy Pl., Socorro, NM 87801 (United States); Linz, Hendrik [Max-Planck-Institut fuer Astronomie (MPIA), Koenigstuhl 17, 69117 Heidelberg (Germany); Araya, Esteban D., E-mail: carrasco@mpifr-bonn.mpg.de [Physics Department, Western Illinois University, 1 University Circle, Macomb, IL 61455 (United States)

2012-06-20

We present new high angular resolution observations toward the driving source of the HH 80-81 jet (IRAS 18162-2048). Continuum emission was observed with the Very Large Array at 7 mm and 1.3 cm, and with the Submillimeter Array at 860 {mu}m, with angular resolutions of {approx}0.''1 and {approx}0.''8, respectively. Submillimeter observations of the sulfur oxide (SO) molecule are reported as well. At 1.3 cm the emission traces the well-known radio jet, while at 7 mm the continuum morphology is quadrupolar and seems to be produced by a combination of free-free and dust emission. An elongated structure perpendicular to the jet remains in the 7 mm image after subtraction of the free-free contribution. This structure is interpreted as a compact accretion disk of {approx}200 AU radius. Our interpretation is favored by the presence of rotation in our SO observations observed at larger scales. The observations presented here add to the small list of cases where the hundred-AU scale emission from a circumstellar disk around a massive protostar has been resolved.

The Role of the Most Luminous Obscured AGNs in Galaxy Assembly at z ∼ 2

Energy Technology Data Exchange (ETDEWEB)

Farrah, Duncan [Department of Physics, Virginia Tech, Blacksburg, VA 24061 (United States); Petty, Sara [Green Science Policy Institute, Berkeley, CA 94709 (United States); Connolly, Brian [Cincinnati Children’s Hospital Medical Center, 3333 Burnet Avenue, Cincinnati, OH 45229 (United States); Blain, Andrew [Department of Physics and Astronomy, University of Leicester, Leicester LE1 7RH (United Kingdom); Efstathiou, Andreas [School of Sciences, European University Cyprus, Diogenes Street, Engomi, 1516 Nicosia (Cyprus); Lacy, Mark [National Radio Astronomy Observatory, 520 Edgemont Road, Charlottesville, VA 22903 (United States); Stern, Daniel; Bridge, Carrie; Eisenhardt, Peter; Moustakas, Leonidas [Jet Propulsion Laboratory, California Institute of Technology, 4800 Oak Grove Drive, Pasadena, CA 91109 (United States); Lake, Sean; Tsai, Chao-Wei [Physics and Astronomy Department, University of California, Los Angeles, CA 90095 (United States); Jarrett, Tom [Department of Astronomy, University of Cape Town, 7700 Rondebosch, Capetown 7700 (South Africa); Benford, Dominic [Observational Cosmology Lab., Code 665, NASA at Goddard Space Flight Center, Greenbelt, MD 20771 (United States); Jones, Suzy [Department of Space, Earth, and Environment, Chalmers University of Technology, Onsala Space Observatory, SE-43992 Onsala (Sweden); Assef, Roberto [Núcleo de Astronomía de la Facultad de Ingeniería, Universidad Diego Portales, Av. Ejército Libertador 441, Santiago (Chile); Wu, Jingwen [National Astronomical Observatories, Chinese Academy of Sciences, 20A Datun Road, Chaoyang District, Beijing, 100012 (China)

2017-08-01

We present Hubble Space Telescope WFC3 F160W imaging and infrared spectral energy distributions for 12 extremely luminous, obscured active galactic nuclei (AGNs) at 1.8 < z < 2.7 selected via “hot, dust-obscured” mid-infrared colors. Their infrared luminosities span (2–15) × 10{sup 13} L {sub ⊙}, making them among the most luminous objects in the universe at z ∼ 2. In all cases, the infrared emission is consistent with arising at least for the most part from AGN activity. The AGN fractional luminosities are higher than those in either submillimeter galaxies or AGNs selected via other mid-infrared criteria. Adopting the G , M {sub 20}, and A morphological parameters, together with traditional classification boundaries, infers that three-quarters of the sample are mergers. Our sample does not, however, show any correlation between the considered morphological parameters and either infrared luminosity or AGN fractional luminosity. Moreover, the asymmetries and effective radii of our sample are distributed identically to those of massive galaxies at z ∼ 2. We conclude that our sample is not preferentially associated with mergers, though a significant merger fraction is still plausible. Instead, we propose that our sample includes examples of the massive galaxy population at z ∼ 2 that harbor a briefly luminous, “flickering” AGN and in which the G and M {sub 20} values have been perturbed due to either the AGN and/or the earliest formation stages of a bulge in an inside-out manner. Furthermore, we find that the mass assembly of the central black holes in our sample leads the mass assembly of any bulge component. Finally, we speculate that our sample represents a small fraction of the immediate antecedents of compact star-forming galaxies at z ∼ 2.

Multidimensional Simulations of Colliding Outbursts from very Massive Stars

Science.gov (United States)

Chen, Ke-Jung; Woosley, Stan

2015-08-01

Massive stars that end their lives with helium cores in the range of 35 to 65 solar masses are known to produce repeated thermonuclear outbursts due to a recurring pair-instability. In some of these events, solar masses of material are ejected in repeated outbursts of several times 1050 erg each. Such models can be used to explain the strong mass loss rates at the last moment before the massive stars die. Collisions between these shells can sometimes produce very luminous transients. Previous 1D studies of these events produce thin,high-density shells as one ejection plows into another. We present the first multidimensional simulations of these collisions, we show that the development of a Rayleigh-Taylor instability truncates the growth of the high density spike and drives mixing between the shells.

X-RAY EMISSION FROM MAGNETIC MASSIVE STARS

International Nuclear Information System (INIS)

Nazé, Yaël; Petit, Véronique; Rinbrand, Melanie; Owocki, Stan; Cohen, David; Ud-Doula, Asif; Wade, Gregg A.

2014-01-01

Magnetically confined winds of early-type stars are expected to be sources of bright and hard X-rays. To clarify the systematics of the observed X-ray properties, we have analyzed a large series of Chandra and XMM-Newton observations, corresponding to all available exposures of known massive magnetic stars (over 100 exposures covering ∼60% of stars compiled in the catalog of Petit et al.). We show that the X-ray luminosity is strongly correlated with the stellar wind mass-loss rate, with a power-law form that is slightly steeper than linear for the majority of the less luminous, lower- M-dot B stars and flattens for the more luminous, higher- M-dot O stars. As the winds are radiatively driven, these scalings can be equivalently written as relations with the bolometric luminosity. The observed X-ray luminosities, and their trend with mass-loss rates, are well reproduced by new MHD models, although a few overluminous stars (mostly rapidly rotating objects) exist. No relation is found between other X-ray properties (plasma temperature, absorption) and stellar or magnetic parameters, contrary to expectations (e.g., higher temperature for stronger mass-loss rate). This suggests that the main driver for the plasma properties is different from the main determinant of the X-ray luminosity. Finally, variations of the X-ray hardnesses and luminosities, in phase with the stellar rotation period, are detected for some objects and they suggest that some temperature stratification exists in massive stars' magnetospheres

Genomic and phylogenetic characterization of luminous bacteria symbiotic with the deep-sea fish Chlorophthalmus albatrossis (Aulopiformes: Chlorophthalmidae).

Science.gov (United States)

Dunlap, Paul V; Ast, Jennifer C

2005-02-01

Bacteria forming light-organ symbiosis with deep-sea chlorophthalmid fishes (Aulopiformes: Chlorophthalmidae) are considered to belong to the species Photobacterium phosphoreum. The identification of these bacteria as P. phosphoreum, however, was based exclusively on phenotypic traits, which may not discriminate between phenetically similar but evolutionarily distinct luminous bacteria. Therefore, to test the species identification of chlorophthalmid symbionts, we carried out a genomotypic (repetitive element palindromic PCR genomic profiling) and phylogenetic analysis on strains isolated from the perirectal light organ of Chlorophthalmus albatrossis. Sequence analysis of the 16S rRNA gene of 10 strains from 5 fish specimens placed these bacteria in a cluster related to but phylogenetically distinct from the type strain of P. phosphoreum, ATCC 11040(T), and the type strain of Photobacterium iliopiscarium, ATCC 51760(T). Analysis of gyrB resolved the C. albatrossis strains as a strongly supported clade distinct from P. phosphoreum and P. iliopiscarium. Genomic profiling of 109 strains from the 5 C. albatrossis specimens revealed a high level of similarity among strains but allowed identification of genomotypically different types from each fish. Representatives of each type were then analyzed phylogenetically, using sequence of the luxABFE genes. As with gyrB, analysis of luxABFE resolved the C. albatrossis strains as a robustly supported clade distinct from P. phosphoreum. Furthermore, other strains of luminous bacteria reported as P. phosphoreum, i.e., NCIMB 844, from the skin of Merluccius capensis (Merlucciidae), NZ-11D, from the light organ of Nezumia aequalis (Macrouridae), and pjapo.1.1, from the light organ of Physiculus japonicus (Moridae), grouped phylogenetically by gyrB and luxABFE with the C. albatrossis strains, not with ATCC 11040(T). These results demonstrate that luminous bacteria symbiotic with C. albatrossis, together with certain other strains of

Study on the Influence Factors of the Luminous Intensity of the Long Afterglow Luminous Paints

Directory of Open Access Journals (Sweden)

Zhao Su

2016-01-01

Full Text Available In order to extend the time afterglow luminous powder, enhancement the brightness of luminous paint, this study explore affect long afterglow energy storage luminous paints brightness of the main factors. Luminous paints were prepared with rare earth aluminate long afterglow luminescent powder, first is luminous powder surface modification, then investigate the influence of light emitting powder content, calcium carbonate, titanium dioxide, nano alumina and other fillers on the luminescent properties of the paints. It was concluded that the water resistance of the luminescent powder is better and the brightness can be improved after the modification of anhydrous alcohol. The addition of nano-alumina can improve the brightness of the system, and can effectively enhance the hardness of the paints. In the paints, the two kinds of components of carbonate and titanium dioxide have little effect on the luminescent brightness of the painting.

THE PANCHROMATIC HUBBLE ANDROMEDA TREASURY. III. MEASURING AGES AND MASSES OF PARTIALLY RESOLVED STELLAR CLUSTERS

Energy Technology Data Exchange (ETDEWEB)

Beerman, Lori C.; Johnson, L. Clifton; Fouesneau, Morgan; Dalcanton, Julianne J.; Weisz, Daniel R.; Williams, Ben F. [Department of Astronomy, University of Washington, Box 351580, Seattle, WA 98195 (United States); Seth, Anil C. [Department of Physics and Astronomy, University of Utah, Salt Lake City, UT 84112 (United States); Bell, Eric F. [Department of Astronomy, University of Michigan, 500 Church Street, Ann Arbor, MI 48109 (United States); Bianchi, Luciana C. [Department of Physics and Astronomy, Johns Hopkins University, 3400 North Charles Street, Baltimore, MD 21218 (United States); Caldwell, Nelson [Harvard-Smithsonian Center for Astrophysics, 60 Garden Street, Cambridge, MA 02138 (United States); Dolphin, Andrew E. [Raytheon Company, 1151 East Hermans Road, Tucson, AZ 85756 (United States); Gouliermis, Dimitrios A. [Zentrum fuer Astronomie, Institut fuer Theoretische Astrophysik, Universitaet Heidelberg, Albert-Ueberle-Strasse 2, D-69120 Heidelberg (Germany); Kalirai, Jason S. [Space Telescope Science Institute, 3700 San Martin Drive, Baltimore, MD 21218 (United States); Larsen, Soren S. [Department of Astrophysics, IMAPP, Radboud University Nijmegen, P.O. Box 9010, NL-6500 GL Nijmegen (Netherlands); Melbourne, Jason L. [Caltech Optical Observatories, Division of Physics, Mathematics and Astronomy, Mail Stop 301-17, California Institute of Technology, Pasadena, CA 91125 (United States); Rix, Hans-Walter [Max-Planck-Institut fuer Astronomie, Koenigstuhl 17, D-69117 Heidelberg (Germany); Skillman, Evan D., E-mail: beermalc@astro.washington.edu [Department of Astronomy, University of Minnesota, 116 Church Street SE, Minneapolis, MN 55455 (United States)

2012-12-01

The apparent age and mass of a stellar cluster can be strongly affected by stochastic sampling of the stellar initial mass function (IMF), when inferred from the integrated color of low-mass clusters ({approx}<10{sup 4} M {sub Sun }). We use simulated star clusters to show that these effects are minimized when the brightest, rapidly evolving stars in a cluster can be resolved, and the light of the fainter, more numerous unresolved stars can be analyzed separately. When comparing the light from the less luminous cluster members to models of unresolved light, more accurate age estimates can be obtained than when analyzing the integrated light from the entire cluster under the assumption that the IMF is fully populated. We show the success of this technique first using simulated clusters, and then with a stellar cluster in M31. This method represents one way of accounting for the discrete, stochastic sampling of the stellar IMF in less massive clusters and can be leveraged in studies of clusters throughout the Local Group and other nearby galaxies.

Ionized Gas Kinematics around an Ultra-luminous X-Ray Source in NGC 5252: Additional Evidence for an Off-nuclear AGN

Energy Technology Data Exchange (ETDEWEB)

Kim, Minjin [Korea Astronomy and Space Science Institute, Daejeon 305-348 (Korea, Republic of); Ho, Luis C. [Kavli Institute for Astronomy and Astrophysics, Peking University, Beijing 100871 (China); Im, Myungshin [Center for the Exploration of the Origin of the Universe (CEOU), Astronomy Program, Department of Physics and Astronomy, Seoul National University, 599 Gwanak-ro, Gwanak-gu, Seoul, 151-742 (Korea, Republic of)

2017-08-01

The Seyfert 2 galaxy NGC 5252 contains a recently identified ultra-luminous X-ray (ULX) source that has been suggested to be a possible candidate off-nuclear low-mass active galactic nucleus. We present follow-up optical integral-field unit observations obtained using Gemini Multi-Object Spectrographs on the Gemini-North telescope. In addition to confirming that the ionized gas in the vicinity of the ULX is kinematically associated with NGC 5252, the new observations reveal ordered motions consistent with rotation around the ULX. The close coincidence of the excitation source of the line-emitting gas with the position of the ULX further suggests that ULX itself is directly responsible for the ionization of the gas. The spatially resolved measurements of [N ii] λ 6584/H α surrounding the ULX indicate a low gas-phase metallicity, consistent with those of other known low-mass active galaxies but not that of its more massive host galaxy. These findings strengthen the proposition that the ULX is not a background source but rather that it is the nucleus of a small, low-mass galaxy accreted by NGC 5252.

An unstable truth: how massive stars get their mass

Science.gov (United States)

Rosen, Anna L.; Krumholz, Mark R.; McKee, Christopher F.; Klein, Richard I.

2016-12-01

The pressure exerted by massive stars' radiation fields is an important mechanism regulating their formation. Detailed simulation of massive star formation therefore requires an accurate treatment of radiation. However, all published simulations have either used a diffusion approximation of limited validity; have only been able to simulate a single star fixed in space, thereby suppressing potentially important instabilities; or did not provide adequate resolution at locations where instabilities may develop. To remedy this, we have developed a new, highly accurate radiation algorithm that properly treats the absorption of the direct radiation field from stars and the re-emission and processing by interstellar dust. We use our new tool to perform 3D radiation-hydrodynamic simulations of the collapse of massive pre-stellar cores with laminar and turbulent initial conditions and properly resolve regions where we expect instabilities to grow. We find that mass is channelled to the stellar system via gravitational and Rayleigh-Taylor (RT) instabilities, in agreement with previous results using stars capable of moving, but in disagreement with methods where the star is held fixed or with simulations that do not adequately resolve the development of RT instabilities. For laminar initial conditions, proper treatment of the direct radiation field produces later onset of instability, but does not suppress it entirely provided the edges of radiation-dominated bubbles are adequately resolved. Instabilities arise immediately for turbulent pre-stellar cores because the initial turbulence seeds the instabilities. Our results suggest that RT features should be present around accreting massive stars throughout their formation.

EXTENDED [C II] EMISSION IN LOCAL LUMINOUS INFRARED GALAXIES

International Nuclear Information System (INIS)

Díaz-Santos, T.; Armus, L.; Surace, J. A.; Charmandaris, V.; Stacey, G.; Murphy, E. J.; Haan, S.; Stierwalt, S.; Evans, A. S.; Malhotra, S.; Appleton, P.; Inami, H.; Magdis, G. E.; Elbaz, D.; Mazzarella, J. M.; Xu, C. K.; Lu, N.; Howell, J. H.; Van der Werf, P. P.; Meijerink, R.

2014-01-01

We present Herschel/PACS observations of extended [C II] 157.7 μm line emission detected on ∼1-10 kpc scales in 60 local luminous infrared galaxies (LIRGs) from the Great Observatories All-sky LIRG Survey. We find that most of the extra-nuclear emission show [C II]/FIR ratios ≥4 × 10 –3 , larger than the mean ratio seen in the nuclei, and similar to those found in the extended disks of normal star-forming galaxies and the diffuse interstellar medium of our Galaxy. The [C II] ''deficits'' found in the most luminous local LIRGs are therefore restricted to their nuclei. There is a trend for LIRGs with warmer nuclei to show larger differences between their nuclear and extra-nuclear [C II]/FIR ratios. We find an anti-correlation between [C II]/FIR and the luminosity surface density, Σ IR , for the extended emission in the spatially resolved galaxies. However, there is an offset between this trend and that found for the LIRG nuclei. We use this offset to derive a beam filling-factor for the star-forming regions within the LIRG disks of ∼6% relative to their nuclei. We confront the observed trend to photo-dissociation region models and find that the slope of the correlation is much shallower than the model predictions. Finally, we compare the correlation found between [C II]/FIR and Σ IR with measurements of high-redshift starbursting IR-luminous galaxies

The coupling between pulsation and mass loss in massive stars

OpenAIRE

Townsend, Rich

2007-01-01

To what extent can pulsational instabilities resolve the mass-loss problem of massive stars? How important is pulsation in structuring and modulating the winds of these stars? What role does pulsation play in redistributing angular momentum in massive stars? Although I cannot offer answers to these questions, I hope at the very least to explain how they come to be asked.

Luminance requirements for lighted signage

Science.gov (United States)

Freyssinier, Jean Paul; Narendran, Nadarajah; Bullough, John D.

2006-08-01

Light-emitting diode (LED) technology is presently targeted to displace traditional light sources in backlighted signage. The literature shows that brightness and contrast are perhaps the two most important elements of a sign that determine its attention-getting capabilities and its legibility. Presently, there are no luminance standards for signage, and the practice of developing brighter signs to compete with signs in adjacent businesses is becoming more commonplace. Sign luminances in such cases may far exceed what people usually need for identifying and reading a sign. Furthermore, the practice of higher sign luminance than needed has many negative consequences, including higher energy use and light pollution. To move toward development of a recommendation for lighted signage, several laboratory human factors evaluations were conducted. A scale model of a storefront was used to present human subjects with a typical red channel-letter sign at luminances ranging from 8 cd/m2 to 1512 cd/m2 under four background luminances typical of nighttime outdoor and daytime inside-mall conditions (1, 100, 300, 1000 cd/m2), from three scaled viewing distances (30, 60, 340 ft), and either in isolation or adjacent to two similar signs. Subjects rated the brightness, acceptability, and ease of reading of the test sign for each combination of sign and background luminances and scaled viewing distances.

Complexity growth in minimal massive 3D gravity

Science.gov (United States)

Qaemmaqami, Mohammad M.

2018-01-01

We study the complexity growth by using "complexity =action " (CA) proposal in the minimal massive 3D gravity (MMG) model which is proposed for resolving the bulk-boundary clash problem of topologically massive gravity (TMG). We observe that the rate of the complexity growth for Banados-Teitelboim-Zanelli (BTZ) black hole saturates the proposed bound by physical mass of the BTZ black hole in the MMG model, when the angular momentum parameter and the inner horizon of black hole goes to zero.

A GIANT RADIO HALO IN THE MASSIVE AND MERGING CLUSTER ABELL 1351

International Nuclear Information System (INIS)

Giacintucci, S.; Venturi, T.; Cassano, R.; Dallacasa, D.; Brunetti, G.

2009-01-01

We report on the detection of diffuse radio emission in the X-ray luminous and massive galaxy cluster A 1351 (z = 0.322) using archival Very Large Array data at 1.4 GHz. Given its central location, morphology, and Mpc-scale extent, we classify the diffuse source as a giant radio halo. X-ray and weak lensing studies show A 1351 to be a system undergoing a major merger. The halo is associated with the most massive substructure. The presence of this source is explained assuming that merger-driven turbulence may re-accelerate high-energy particles in the intracluster medium and generate diffuse radio emission on the cluster scale. The position of A 1351 in the log P 1.4GHz -log L X plane is consistent with that of all other radio-halo clusters known to date, supporting a causal connection between the unrelaxed dynamical state of massive (>10 15 M sun ) clusters and the presence of giant radio halos.

Ages of young star clusters, massive blue stragglers, and the upper mass limit of stars: Analyzing age-dependent stellar mass functions

Energy Technology Data Exchange (ETDEWEB)

Schneider, F. R. N.; Izzard, R. G.; Langer, N.; Stolte, A.; Hußmann, B. [Argelander-Institut für Astronomie der Universität Bonn, Auf dem Hügel 71, D-53121 Bonn (Germany); De Mink, S. E. [Observatories of the Carnegie Institution for Science, 813 Santa Barbara St, Pasadena, CA 91101 (United States); De Koter, A.; Sana, H. [Astronomical Institute " Anton Pannekoek" , Amsterdam University, Science Park 904, 1098 XH, Amsterdam (Netherlands); Gvaramadze, V. V. [Sternberg Astronomical Institute, Lomonosov Moscow State University, Universitetskij Pr. 13, Moscow 119992 (Russian Federation); Liermann, A., E-mail: fschneid@astro.uni-bonn.de [Max Planck Institut für Radioastronomie, Auf dem Hügel 69, D-53121 Bonn (Germany)

2014-01-10

Massive stars rapidly change their masses through strong stellar winds and mass transfer in binary systems. The latter aspect is important for populations of massive stars as more than 70% of all O stars are expected to interact with a binary companion during their lifetime. We show that such mass changes leave characteristic signatures in stellar mass functions of young star clusters that can be used to infer their ages and to identify products of binary evolution. We model the observed present-day mass functions of the young Galactic Arches and Quintuplet star clusters using our rapid binary evolution code. We find that the shaping of the mass function by stellar wind mass loss allows us to determine the cluster ages as 3.5 ± 0.7 Myr and 4.8 ± 1.1 Myr, respectively. Exploiting the effects of binary mass exchange on the cluster mass function, we find that the most massive stars in both clusters are rejuvenated products of binary mass transfer, i.e., the massive counterpart of classical blue straggler stars. This resolves the problem of an apparent age spread among the most luminous stars exceeding the expected duration of star formation in these clusters. We perform Monte Carlo simulations to probe stochastic sampling, which support the idea of the most massive stars being rejuvenated binary products. We find that the most massive star is expected to be a binary product after 1.0 ± 0.7 Myr in Arches and after 1.7 ± 1.0 Myr in Quintuplet. Today, the most massive 9 ± 3 stars in Arches and 8 ± 3 in Quintuplet are expected to be such objects. Our findings have strong implications for the stellar upper mass limit and solve the discrepancy between the claimed 150 M {sub ☉} limit and observations of four stars with initial masses of 165-320 M {sub ☉} in R136 and of supernova 2007bi, which is thought to be a pair-instability supernova from an initial 250 M {sub ☉} star. Using the stellar population of R136, we revise the upper mass limit to values in the range

Ages of young star clusters, massive blue stragglers, and the upper mass limit of stars: Analyzing age-dependent stellar mass functions

International Nuclear Information System (INIS)

Schneider, F. R. N.; Izzard, R. G.; Langer, N.; Stolte, A.; Hußmann, B.; De Mink, S. E.; Anton Pannekoek, Amsterdam University, Science Park 904, 1098 XH, Amsterdam (Netherlands))" data-affiliation=" (Astronomical Institute Anton Pannekoek, Amsterdam University, Science Park 904, 1098 XH, Amsterdam (Netherlands))" >De Koter, A.; Anton Pannekoek, Amsterdam University, Science Park 904, 1098 XH, Amsterdam (Netherlands))" data-affiliation=" (Astronomical Institute Anton Pannekoek, Amsterdam University, Science Park 904, 1098 XH, Amsterdam (Netherlands))" >Sana, H.; Gvaramadze, V. V.; Liermann, A.

2014-01-01

Massive stars rapidly change their masses through strong stellar winds and mass transfer in binary systems. The latter aspect is important for populations of massive stars as more than 70% of all O stars are expected to interact with a binary companion during their lifetime. We show that such mass changes leave characteristic signatures in stellar mass functions of young star clusters that can be used to infer their ages and to identify products of binary evolution. We model the observed present-day mass functions of the young Galactic Arches and Quintuplet star clusters using our rapid binary evolution code. We find that the shaping of the mass function by stellar wind mass loss allows us to determine the cluster ages as 3.5 ± 0.7 Myr and 4.8 ± 1.1 Myr, respectively. Exploiting the effects of binary mass exchange on the cluster mass function, we find that the most massive stars in both clusters are rejuvenated products of binary mass transfer, i.e., the massive counterpart of classical blue straggler stars. This resolves the problem of an apparent age spread among the most luminous stars exceeding the expected duration of star formation in these clusters. We perform Monte Carlo simulations to probe stochastic sampling, which support the idea of the most massive stars being rejuvenated binary products. We find that the most massive star is expected to be a binary product after 1.0 ± 0.7 Myr in Arches and after 1.7 ± 1.0 Myr in Quintuplet. Today, the most massive 9 ± 3 stars in Arches and 8 ± 3 in Quintuplet are expected to be such objects. Our findings have strong implications for the stellar upper mass limit and solve the discrepancy between the claimed 150 M ☉ limit and observations of four stars with initial masses of 165-320 M ☉ in R136 and of supernova 2007bi, which is thought to be a pair-instability supernova from an initial 250 M ☉ star. Using the stellar population of R136, we revise the upper mass limit to values in the range 200-500 M ☉ .

Ages of Young Star Clusters, Massive Blue Stragglers, and the Upper Mass Limit of Stars: Analyzing Age-dependent Stellar Mass Functions

Science.gov (United States)

Schneider, F. R. N.; Izzard, R. G.; de Mink, S. E.; Langer, N.; Stolte, A.; de Koter, A.; Gvaramadze, V. V.; Hußmann, B.; Liermann, A.; Sana, H.

2014-01-01

Massive stars rapidly change their masses through strong stellar winds and mass transfer in binary systems. The latter aspect is important for populations of massive stars as more than 70% of all O stars are expected to interact with a binary companion during their lifetime. We show that such mass changes leave characteristic signatures in stellar mass functions of young star clusters that can be used to infer their ages and to identify products of binary evolution. We model the observed present-day mass functions of the young Galactic Arches and Quintuplet star clusters using our rapid binary evolution code. We find that the shaping of the mass function by stellar wind mass loss allows us to determine the cluster ages as 3.5 ± 0.7 Myr and 4.8 ± 1.1 Myr, respectively. Exploiting the effects of binary mass exchange on the cluster mass function, we find that the most massive stars in both clusters are rejuvenated products of binary mass transfer, i.e., the massive counterpart of classical blue straggler stars. This resolves the problem of an apparent age spread among the most luminous stars exceeding the expected duration of star formation in these clusters. We perform Monte Carlo simulations to probe stochastic sampling, which support the idea of the most massive stars being rejuvenated binary products. We find that the most massive star is expected to be a binary product after 1.0 ± 0.7 Myr in Arches and after 1.7 ± 1.0 Myr in Quintuplet. Today, the most massive 9 ± 3 stars in Arches and 8 ± 3 in Quintuplet are expected to be such objects. Our findings have strong implications for the stellar upper mass limit and solve the discrepancy between the claimed 150 M ⊙ limit and observations of four stars with initial masses of 165-320 M ⊙ in R136 and of supernova 2007bi, which is thought to be a pair-instability supernova from an initial 250 M ⊙ star. Using the stellar population of R136, we revise the upper mass limit to values in the range 200-500 M ⊙.

Active Luminous Blue Variables in the Large Magellanic Cloud

Energy Technology Data Exchange (ETDEWEB)

Walborn, Nolan R. [Space Telescope Science Institute, 3700 San Martin Drive, Baltimore, MD 21218 (United States); Gamen, Roberto C.; Lajús, Eduardo Fernández [Instituto de Astrofísica de La Plata, CONICET–UNLP and Facultad de Ciencias Astronómicas y Geofísicas, UNLP, Paseo del Bosque s/n, La Plata (Argentina); Morrell, Nidia I. [Las Campanas Observatory, Carnegie Observatories, Casilla 601, La Serena (Chile); Barbá, Rodolfo H. [Departamento de Física y Astronomía, Universidad de La Serena, Cisternas 1200 Norte, La Serena (Chile); Angeloni, Rodolfo, E-mail: walborn@stsci.edu, E-mail: rgamen@fcaglp.unlp.edu.ar, E-mail: eflajus@fcaglp.unlp.edu.ar, E-mail: nmorrell@lco.cl, E-mail: rbarba@dfuls.cl, E-mail: rangelon@gemini.edu [Gemini Observatory, Colina El Pino, Casilla 603, La Serena (Chile)

2017-07-01

We present extensive spectroscopic and photometric monitoring of two famous and currently highly active luminous blue variables (LBVs) in the Large Magellanic Cloud (LMC), together with more limited coverage of three further, lesser known members of the class. R127 was discovered as an Ofpe/WN9 star in the 1970s but entered a classical LBV outburst in or about 1980 that is still in progress, thus enlightening us about the minimum state of such objects. R71 is currently the most luminous star in the LMC and continues to provide surprises, such as the appearance of [Ca ii] emission lines, as its spectral type becomes unprecedentedly late. Most recently, R71 has developed inverse P Cyg profiles in many metal lines. The other objects are as follows: HDE 269582, now a “second R127” that has been followed from Ofpe/WN9 to A type in its current outburst; HDE 269216, which changed from late B in 2014 to AF in 2016, its first observed outburst; and R143 in the 30 Doradus outskirts. The light curves and spectroscopic transformations are correlated in remarkable detail and their extreme reproducibility is emphasized, both for a given object and among all of them. It is now believed that some LBVs proceed directly to core collapse. One of these unstable LMC objects may thus oblige in the near future, teaching us even more about the final stages of massive stellar evolution.

Active Luminous Blue Variables in the Large Magellanic Cloud

Science.gov (United States)

Walborn, Nolan R.; Gamen, Roberto C.; Morrell, Nidia I.; Barbá, Rodolfo H.; Fernández Lajús, Eduardo; Angeloni, Rodolfo

2017-07-01

We present extensive spectroscopic and photometric monitoring of two famous and currently highly active luminous blue variables (LBVs) in the Large Magellanic Cloud (LMC), together with more limited coverage of three further, lesser known members of the class. R127 was discovered as an Ofpe/WN9 star in the 1970s but entered a classical LBV outburst in or about 1980 that is still in progress, thus enlightening us about the minimum state of such objects. R71 is currently the most luminous star in the LMC and continues to provide surprises, such as the appearance of [Ca II] emission lines, as its spectral type becomes unprecedentedly late. Most recently, R71 has developed inverse P Cyg profiles in many metal lines. The other objects are as follows: HDE 269582, now a “second R127” that has been followed from Ofpe/WN9 to A type in its current outburst; HDE 269216, which changed from late B in 2014 to AF in 2016, its first observed outburst; and R143 in the 30 Doradus outskirts. The light curves and spectroscopic transformations are correlated in remarkable detail and their extreme reproducibility is emphasized, both for a given object and among all of them. It is now believed that some LBVs proceed directly to core collapse. One of these unstable LMC objects may thus oblige in the near future, teaching us even more about the final stages of massive stellar evolution.

Active Luminous Blue Variables in the Large Magellanic Cloud

International Nuclear Information System (INIS)

Walborn, Nolan R.; Gamen, Roberto C.; Lajús, Eduardo Fernández; Morrell, Nidia I.; Barbá, Rodolfo H.; Angeloni, Rodolfo

2017-01-01

We present extensive spectroscopic and photometric monitoring of two famous and currently highly active luminous blue variables (LBVs) in the Large Magellanic Cloud (LMC), together with more limited coverage of three further, lesser known members of the class. R127 was discovered as an Ofpe/WN9 star in the 1970s but entered a classical LBV outburst in or about 1980 that is still in progress, thus enlightening us about the minimum state of such objects. R71 is currently the most luminous star in the LMC and continues to provide surprises, such as the appearance of [Ca ii] emission lines, as its spectral type becomes unprecedentedly late. Most recently, R71 has developed inverse P Cyg profiles in many metal lines. The other objects are as follows: HDE 269582, now a “second R127” that has been followed from Ofpe/WN9 to A type in its current outburst; HDE 269216, which changed from late B in 2014 to AF in 2016, its first observed outburst; and R143 in the 30 Doradus outskirts. The light curves and spectroscopic transformations are correlated in remarkable detail and their extreme reproducibility is emphasized, both for a given object and among all of them. It is now believed that some LBVs proceed directly to core collapse. One of these unstable LMC objects may thus oblige in the near future, teaching us even more about the final stages of massive stellar evolution.

Two extremely luminous WN stars in the Galactic center with circumstellar emission from dust and gas

OpenAIRE

Barniske, A.; Oskinova, L. M.; Hamann, W. -R.

2008-01-01

We study relatively isolated massive WN-type stars in the Galactic center. The K-band spectra of WR102ka and WR102c are exploited to infer the stellar parameters and to compute synthetic stellar spectra using the Potsdam Wolf-Rayet (PoWR) model atmosphere code. These models are combined with dust-shell models for analyzing the Spitzer IRS spectra of these objects. Archival IR images complement the interpretation. We report that WR102ka and WR102c are among the most luminous stars in the Milky...

SPATIALLY RESOLVED [Fe II] 1.64 μm EMISSION IN NGC 5135: CLUES FOR UNDERSTANDING THE ORIGIN OF THE HARD X-RAYS IN LUMINOUS INFRARED GALAXIES

International Nuclear Information System (INIS)

Colina, L.; Pereira-Santaella, M.; Alonso-Herrero, A.; Arribas, S.; Bedregal, A. G.

2012-01-01

Spatially resolved near-IR and X-ray imaging of the central region of the luminous infrared galaxy (LIRG) NGC 5135 is presented. The kinematical signatures of strong outflows are detected in the [Fe II] 1.64 μm emission line in a compact region at 0.9 kpc from the nucleus. The derived mechanical energy release is consistent with a supernova rate of 0.05-0.1 yr –1 . The apex of the outflowing gas spatially coincides with the strongest [Fe II] emission peak and with the dominant component of the extranuclear hard X-ray emission. All these features provide evidence for a plausible direct physical link between supernova-driven outflows and the hard X-ray emitting gas in an LIRG. This result is consistent with model predictions of starbursts concentrated in small volumes and with high thermalization efficiencies. A single high-mass X-ray binary (HMXB) as the major source of the hard X-ray emission, although not favored, cannot be ruled out. Outside the active galactic nucleus, the hard X-ray emission in NGC 5135 appears to be dominated by the hot interstellar medium produced by supernova explosions in a compact star-forming region, and not by the emission due to HMXBs. If this scenario is common to (ultra)luminous infrared galaxies, the hard X-rays would only trace the most compact (≤100 pc) regions with high supernova and star formation densities, therefore a lower limit to their integrated star formation. The star formation rate derived in NGC 5135 based on its hard X-ray luminosity is a factor of two and four lower than the values obtained from the 24 μm and soft X-ray luminosities, respectively.

Effects of absolute luminance and luminance contrast on visual search in low mesopic environments.

Science.gov (United States)

Hunter, Mathew; Godde, Ben; Olk, Bettina

2018-03-26

Diverse adaptive visual processing mechanisms allow us to complete visual search tasks in a wide visual photopic range (>0.6 cd/m 2 ). Whether search strategies or mechanisms known from this range extend below, in the mesopic and scotopic luminance spectra (search in more complex-feature and conjunction-search paradigms. The results verify the previously reported deficiency windows defined by an interaction of base luminance and luminance contrast for more complex visual-search tasks. Based on significant regression analyses, a more precise definition of the magnitude of contribution of different contrast parameters. Characterized feature search patterns had approximately a 2.5:1 ratio of contribution from the Michelson contrast property relative to Weber contrast, whereas the ratio was approximately 1:1 in a serial-search condition. The results implicate near-complete magnocellular isolation in a visual-search paradigm that has yet to be demonstrated. Our analyses provide a new method of characterizing visual search and the first insight in its underlying mechanisms in luminance environments in the low mesopic and scotopic spectra.

Daylight calculations using constant luminance curves

Energy Technology Data Exchange (ETDEWEB)

Betman, E. [CRICYT, Mendoza (Argentina). Laboratorio de Ambiente Humano y Vivienda

2005-02-01

This paper presents a simple method to manually estimate daylight availability and to make daylight calculations using constant luminance curves calculated with local illuminance and irradiance data and the all-weather model for sky luminance distribution developed in the Atmospheric Science Research Center of the University of New York (ARSC) by Richard Perez et al. Work with constant luminance curves has the advantage that daylight calculations include the problem's directionality and preserve the information of the luminous climate of the place. This permits accurate knowledge of the resource and a strong basis to establish conclusions concerning topics related to the energy efficiency and comfort in buildings. The characteristics of the proposed method are compared with the method that uses the daylight factor. (author)

EVOLUTION OF THE MOST LUMINOUS DUSTY GALAXIES

International Nuclear Information System (INIS)

Weedman, Daniel W.; Houck, James R.

2009-01-01

A summary of mid-infrared continuum luminosities arising from dust is given for very luminous galaxies, L IR > 10 12 L sun , with 0.005 0.7 in the 9.7 μm silicate absorption feature (i.e., half of the continuum is absorbed) and having equivalent width of the 6.2 μm polycyclic aromatic hydrocarbon feature ν (8 μm) for the most luminous obscured AGNs is found to scale as (1+z) 2.6 to z = 2.8. For unobscured AGNs, the scaling with redshift is similar, but luminosities νL ν (8 μm) are approximately three times greater for the most luminous sources. Using both obscured and unobscured AGNs having total infrared fluxes from the Infrared Astronomical Satellite, empirical relations are found between νL ν (8 μm) and L IR . Combining these relations with the redshift scaling of luminosity, we conclude that the total infrared luminosities for the most luminous obscured AGNs, L IR (AGN obscured ) in L sun , scale as log L IR (AGN obscured ) = 12.3 ± 0.25 + 2.6(±0.3)log(1+z), and for the most luminous unobscured AGNs, scale as log L IR (AGN1) = 12.6(±0.15) + 2.6(±0.3)log(1+z). We previously determined that the most luminous starbursts scale as log L IR (SB) = 11.8 ± 0.3 + 2.5(±0.3)log(1+z), indicating that the most luminous AGNs are about 10 times more luminous than the most luminous starbursts. Results are consistent with obscured and unobscured AGNs having the same total luminosities with differences arising only from orientation, such that the obscured AGNs are observed through very dusty clouds which extinct about 50% of the intrinsic luminosity at 8 μm. Extrapolations of observable f ν (24 μm) to z = 6 are made using evolution results for these luminous sources. Both obscured and unobscured AGNs should be detected to z ∼ 6 by Spitzer surveys with f ν (24 μm) > 0.3 mJy, even without luminosity evolution for z > 2.5. By contrast, the most luminous starbursts cannot be detected for z > 3, even if luminosity evolution continues beyond z = 2.5.

A Practical Device for Measuring the Luminance Distribution

Directory of Open Access Journals (Sweden)

Thijs Kruisselbrink

2017-06-01

Full Text Available Various applications in building lighting such as automated daylight systems, dynamic lighting control systems, lighting simulations, and glare analyzes can be optimized using information on the actual luminance distributions of the surroundings. Currently, commercially available luminance distribution measurement devices are often not suitable for these kind of applications or simply too expensive for broad application. This paper describes the development of a practical and autonomous luminance distribution measurement device based on a credit card-sized single-board computer and a camera system. The luminance distribution was determined by capturing High Dynamic Range images and translating the RGB information to the CIE XYZ color space. The High Dynamic Range technology was essential to accurately capture the data needed to calculate the luminance distribution because it allows to capture luminance ranges occurring in real scenarios. The measurement results were represented in accordance with established methods in the field of daylighting. Measurements showed that the accuracy of the luminance distribution measurement device ranged from 5% to 20% (worst case which was deemed acceptable for practical measurements and broad applications in the building realm.

The Extremely Luminous Quasar Survey (ELQS) in SDSS and the high-z bright-end Quasar Luminosity Function

Science.gov (United States)

Schindler, Jan-Torge; Fan, Xiaohui; McGreer, Ian

2018-01-01

Studies of the most luminous quasars at high redshift directly probe the evolution of the most massive black holes in the early Universe and their connection to massive galaxy formation. Unfortunately, extremely luminous quasars at high redshift are very rare objects. Only wide area surveys have a chance to constrain their population. The Sloan Digital Sky Survey (SDSS) nd the Baryon Oscillation Spectroscopic Survey (BOSS) have so far provided the most widely adopted measurements of the type I quasar luminosity function (QLF) at z>3. However, a careful re-examination of the SDSS quasar sample revealed that the SDSS quasar selection is in fact missing a significant fraction of $z~3$ quasars at the brightest end.We have identified the purely optical color selection of SDSS, where quasars at these redshifts are strongly contaminated by late-type dwarfs, and the spectroscopic incompleteness of the SDSS footprint as the main reasons. Therefore we have designed the Extremely Luminous Quasar Survey (ELQS), based on a novel near-infrared JKW2 color cut using WISE AllWISE and 2MASS all-sky photometry, to yield high completeness for very bright (i < 18.0) quasars in the redshift range of 2.8<= z<=5.0. It effectively uses Random Forest machine-learning algorithms on SDSS and WISE photometry for quasar-star classification and photometric redshift estimation.The ELQS is spectroscopically following up ~230 new quasar candidates in an area of ~12000 deg2 in the SDSS footprint, to obtain a well-defined and complete quasar sample for an accurate measurement of the bright-end quasar luminosity function (QLF) at 2.8<= z<=5.0. So far the ELQS has identified 75 bright new quasars in this redshift range and observations of the fall sky will continue until the end of the year. At the AAS winter meeting we will present the full spectroscopic results of the survey, including a re-estimation and extension of the high-z QLF toward higher luminosities.

A LUMINOUS GAMMA-RAY BINARY IN THE LARGE MAGELLANIC CLOUD

Energy Technology Data Exchange (ETDEWEB)

Corbet, R. H. D. [University of Maryland, Baltimore County, and X-ray Astrophysics Laboratory, Code 662 NASA Goddard Space Flight Center, Greenbelt Rd., MD 20771 (United States); Chomiuk, L.; Strader, J. [Department of Physics and Astronomy, Michigan State University, East Lansing, MI 48824 (United States); Coe, M. J. [University of Southampton, School of Physics and Astronomy, Southampton SO17 1BJ (United Kingdom); Coley, J. B. [NASA Postdoctoral Program, and Astroparticle Physics Laboratory, Code 661 NASA Goddard Space Flight Center, Greenbelt Rd., MD 20771 (United States); Dubus, G. [Institut de Planétologie et d’Astrophysique de Grenoble, Univ. Grenoble Alpes, CNRS, F-38000 Grenoble (France); Edwards, P. G.; Stevens, J. [Commonwealth Scientific and Industrial Research Organisation Astronomy and Space Science, P.O. Box 76, Epping, New South Wales 1710 (Australia); Martin, P. [Institut de Recherche en Astrophysique et Planétologie, Université de Toulouse, CNRS, F-31028 Toulouse cedex 4 (France); McBride, V. A.; Townsend, L. J. [Department of Astronomy, University of Cape Town, Private Bag X3, Rondebosch 7701 (South Africa); Udalski, A. [Warsaw University Observatory, Al. Ujazdowskie 4, 00-478 Warszawa (Poland)

2016-10-01

Gamma-ray binaries consist of a neutron star or a black hole interacting with a normal star to produce gamma-ray emission that dominates the radiative output of the system. Only a handful of such systems have been previously discovered, all within our Galaxy. Here, we report the discovery of a luminous gamma-ray binary in the Large Magellanic Cloud, found with the Fermi Large Area Telescope (LAT), from a search for periodic modulation in all sources in the third Fermi LAT catalog. This is the first such system to be found outside the Milky Way. The system has an orbital period of 10.3 days, and is associated with a massive O5III star located in the supernova remnant DEM L241, previously identified as the candidate high-mass X-ray binary (HMXB) CXOU J053600.0–673507. X-ray and radio emission are also modulated on the 10.3 day period, but are in anti-phase with the gamma-ray modulation. Optical radial velocity measurements suggest that the system contains a neutron star. The source is significantly more luminous than similar sources in the Milky Way, at radio, optical, X-ray, and gamma-ray wavelengths. The detection of this extra-galactic system, but no new Galactic systems, raises the possibility that the predicted number of gamma-ray binaries in our Galaxy has been overestimated, and that HMXBs may be born containing relatively slowly rotating neutron stars.

Influence of Spatial and Chromatic Noise on Luminance Discrimination.

Science.gov (United States)

Miquilini, Leticia; Walker, Natalie A; Odigie, Erika A; Guimarães, Diego Leite; Salomão, Railson Cruz; Lacerda, Eliza Maria Costa Brito; Cortes, Maria Izabel Tentes; de Lima Silveira, Luiz Carlos; Fitzgerald, Malinda E C; Ventura, Dora Fix; Souza, Givago Silva

2017-12-05

Pseudoisochromatic figures are designed to base discrimination of a chromatic target from a background solely on the chromatic differences. This is accomplished by the introduction of luminance and spatial noise thereby eliminating these two dimensions as cues. The inverse rationale could also be applied to luminance discrimination, if spatial and chromatic noise are used to mask those cues. In this current study estimate of luminance contrast thresholds were conducted using a novel stimulus, based on the use of chromatic and spatial noise to mask the use of these cues in a luminance discrimination task. This was accomplished by presenting stimuli composed of a mosaic of circles colored randomly. A Landolt-C target differed from the background only by the luminance. The luminance contrast thresholds were estimated for different chromatic noise saturation conditions and compared to luminance contrast thresholds estimated using the same target in a non-mosaic stimulus. Moreover, the influence of the chromatic content in the noise on the luminance contrast threshold was also investigated. Luminance contrast threshold was dependent on the chromaticity noise strength. It was 10-fold higher than thresholds estimated from non-mosaic stimulus, but they were independent of colour space location in which the noise was modulated. The present study introduces a new method to investigate luminance vision intended for both basic science and clinical applications.

Conjunctions of colour, luminance and orientation: the role of colour and luminance contrast on saliency and proximity grouping in texture segregation.

Science.gov (United States)

Leonards, U; Singer, W

2000-01-01

To examine whether perceptual grouping on the basis of orientation can be performed simultaneously with or only subsequently to grouping according to colour or luminance, we tested whether subjects are able to segregate arrays of texture elements that differ from surrounding elements by conjunctions of either (i) colour and orientation, or (ii) luminance contrast and orientation, or (iii) luminance contrast polarity and orientation. Subjects were able to use conjunctions between luminance and orientation for segregation but not conjunctions between colour or contrast polarity and orientation. Our results suggest that (i) in agreement with earlier findings, there seem to exist no specific conjunction detectors for colour and orientation or contrast polarity and orientation, and (ii) when orientation defined textures are to be distinguished by virtue of differences in luminance, colour, or contrast polarity, luminance provides a much stronger cue than colour or contrast polarity for saliency-based orientation grouping.

Rise of the Titans: A Dusty, Hyper-luminous “870 μm Riser” Galaxy at z ˜ 6

Science.gov (United States)

Riechers, Dominik A.; Leung, T. K. Daisy; Ivison, Rob J.; Pérez-Fournon, Ismael; Lewis, Alexander J. R.; Marques-Chaves, Rui; Oteo, Iván; Clements, Dave L.; Cooray, Asantha; Greenslade, Josh; Martínez-Navajas, Paloma; Oliver, Seb; Rigopoulou, Dimitra; Scott, Douglas; Weiss, Axel

2017-11-01

We report the detection of ADFS-27, a dusty, starbursting major merger at a redshift of z = 5.655, using the Atacama Large Millimeter/submillimeter Array (ALMA). ADFS-27 was selected from Herschel/Spectral and Photometric Imaging Receiver (SPIRE) and APEX/LABOCA data as an extremely red “870 μm riser” (I.e., {S}250μ {{m}}< {S}350μ {{m}}< {S}500μ {{m}}< {S}870μ {{m}}), demonstrating the utility of this technique to identify some of the highest-redshift dusty galaxies. A scan of the 3 mm atmospheric window with ALMA yields detections of CO(J = 5 → 4) and CO(J = 6 → 5) emission, and a tentative detection of H2O(211 → 202) emission, which provides an unambiguous redshift measurement. The strength of the CO lines implies a large molecular gas reservoir with a mass of M gas = 2.5 × 1011 ({α }{CO}/0.8)(0.39/{r}51) M ⊙, sufficient to maintain its ˜2400 M ⊙ yr-1 starburst for at least ˜100 Myr. The 870 μm dust continuum emission is resolved into two components, 1.8 and 2.1 kpc in diameter, separated by 9.0 kpc, with comparable dust luminosities, suggesting an ongoing major merger. The infrared luminosity of L IR ≃ 2.4 × 1013 L ⊙ implies that this system represents a binary hyper-luminous infrared galaxy, the most distant of its kind presently known. This also implies star formation rate surface densities of {{{Σ }}}{SFR}=730 and 750 M ⊙ yr-1 kpc2, consistent with a binary “maximum starburst.” The discovery of this rare system is consistent with a significantly higher space density than previously thought for the most luminous dusty starbursts within the first billion years of cosmic time, easing tensions regarding the space densities of z ˜ 6 quasars and massive quiescent galaxies at z ≳ 3.

Extraordinary luminous soft X-ray transient MAXI J0158–744 as an ignition of a nova on a very massive O-Ne white dwarf

Energy Technology Data Exchange (ETDEWEB)

Morii, M.; Serino, M.; Mihara, T.; Sugizaki, M. [MAXI Team, Institute of Physical and Chemical Research (RIKEN), 2-1 Hirosawa, Wako, Saitama 351-0198 (Japan); Tomida, H.; Kimura, M.; Nakahira, S. [ISS Science Project Office, Institute of Space and Astronautical Science, Japan Aerospace Exploration Agency, 2-1-1 Sengen, Tsukuba, Ibaraki 305-8505 (Japan); Suwa, F.; Negoro, H. [Department of Physics, Nihon University, 1-8-14 Surugadai, Chiyoda, Tokyo 101-8308 (Japan); Kennea, J. A.; Pritchard, T. [Department of Astronomy and Astrophysics, The Pennsylvania State University, 525 Davey Laboratory, University Park, PA 16802 (United States); Page, K. L.; Osborne, J. P. [Department of Physics and Astronomy, University of Leicester, University Road, Leicester LE1 7RH (United Kingdom); Curran, P. A. [International Centre for Radio Astronomy Research, Curtin University, GPO Box U1987, Perth, WA 6845 (Australia); Walter, F. M. [Department of Physics and Astronomy, Stony Brook University, Stony Brook, NY 11794-3800 (United States); Kuin, N. P. M. [Mullard Space Science Laboratory, University College London, Holmbury St Mary, Dorking, Surrey RH5 6NT (United Kingdom); Hiroi, K. [Department of Astronomy, Kyoto University, Oiwake-cho, Sakyo-ku, Kyoto 606-8502 (Japan); Usui, R.; Kawai, N. [Department of Physics, Tokyo Institute of Technology, Ookayama 2-12-1, Meguro-ku, Tokyo 152-8551 (Japan); Gehrels, N. [NASA Goddard Space Flight Center, Greenbelt, MD 20771 (United States); and others

2013-12-20

We present the observation of an extraordinary luminous soft X-ray transient, MAXI J0158–744, by the Monitor of All-sky X-ray Image (MAXI) on 2011 November 11. This transient is characterized by a soft X-ray spectrum, a short duration (1.3 × 10{sup 3} s < ΔT{sub d} < 1.10 × 10{sup 4} s), a rapid rise (<5.5 × 10{sup 3} s), and a huge peak luminosity of 2 × 10{sup 40} erg s{sup –1} in 0.7-7.0 keV band. With Swift observations and optical spectroscopy from the Small and Moderate Aperture Research Telescope System, we confirmed that the transient is a nova explosion, on a white dwarf in a binary with a Be star, located near the Small Magellanic Cloud. An early turn-on of the super-soft X-ray source (SSS) phase (<0.44 days), the short SSS phase duration of about one month, and a 0.92 keV neon emission line found in the third MAXI scan, 1296 s after the first detection, suggest that the explosion involves a small amount of ejecta and is produced on an unusually massive O-Ne white dwarf close to, or possibly over, the Chandrasekhar limit. We propose that the huge luminosity detected with MAXI was due to the fireball phase, a direct manifestation of the ignition of the thermonuclear runaway process in a nova explosion.

Chromatic blur perception in the presence of luminance contrast.

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Jennings, Ben J; Kingdom, Frederick A A

2017-06-01

Hel-Or showed that blurring the chromatic but not the luminance layer of an image of a natural scene failed to elicit any impression of blur. Subsequent studies have suggested that this effect is due either to chromatic blur being masked by spatially contiguous luminance edges in the scene (Journal of Vision 13 (2013) 14), or to a relatively compressed transducer function for chromatic blur (Journal of Vision 15 (2015) 6). To test between the two explanations we conducted experiments using as stimuli both images of natural scenes as well as simple edges. First, we found that in color-and-luminance images of natural scenes more chromatic blur was needed to perceptually match a given level of blur in an isoluminant, i.e. colour-only scene. However, when the luminance layer in the scene was rotated relative to the chromatic layer, thus removing the colour-luminance edge correlations, the matched blur levels were near equal. Both results are consistent with Sharman et al.'s explanation. Second, when observers matched the blurs of luminance-only with isoluminant scenes, the matched blurs were equal, against Kingdom et al.'s prediction. Third, we measured the perceived blur in a square-wave as a function of (i) contrast (ii) number of luminance edges and (iii) the relative spatial phase between the colour and luminance edges. We found that the perceived chromatic blur was dependent on both relative phase and the number of luminance edges, or dependent on the luminance contrast if only a single edge is present. We conclude that this Hel-Or effect is largely due to masking of chromatic blur by spatially contiguous luminance edges. Copyright © 2017 Elsevier Ltd. All rights reserved.

The dynamical fingerprint of core scouring in massive elliptical galaxies

International Nuclear Information System (INIS)

Thomas, J.; Saglia, R. P.; Bender, R.; Erwin, P.; Fabricius, M.

2014-01-01

The most massive elliptical galaxies have low-density centers or cores that differ dramatically from the high-density centers of less massive ellipticals and bulges of disk galaxies. These cores have been interpreted as the result of mergers of supermassive black hole binaries, which depopulate galaxy centers by gravitationally slingshotting central stars toward large radii. Such binaries naturally form in mergers of luminous galaxies. Here, we analyze the population of central stellar orbits in 11 massive elliptical galaxies that we observed with the integral field spectrograph SINFONI at the European Southern Observatory Very Large Telescope. Our dynamical analysis is orbit-based and includes the effects of a central black hole, the mass distribution of the stars, and a dark matter halo. We show that the use of integral field kinematics and the inclusion of dark matter is important to conclude on the distribution of stellar orbits in galaxy centers. Six of our galaxies are core galaxies. In these six galaxies, but not in the galaxies without cores, we detect a coherent lack of stars on radial orbits in the core region and a uniform excess of radial orbits outside of it: when scaled by the core radius r b , the radial profiles of the classical anisotropy parameter β(r) are nearly identical in core galaxies. Moreover, they quantitatively match the predictions of black hole binary simulations, providing the first convincing dynamical evidence for core scouring in the most massive elliptical galaxies.

Korsakoff's psychosis due to massive beer intake provoked by diabetes insipidus.

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Farr, R W; Blankenship, D C; Viti, A; Albrink, M J

1988-05-01

Posttraumatic diabetes insipidus, acute pancreatitis, and Wernicke's encephalopathy and Korsakoff's psychosis in a 33-year-old white male alcohol abuser resulted in near-fatal cardiovascular collapse. The Wernicke's encephalopathy and Korsakoff's psychosis resulted from drinking massive quantities of beer to satisfy the thirst induced by diabetes insipidus. Although the diabetes insipidus was controlled with vasopressin, and the need for vasopressin resolved two months after diagnosis, the Wernicke-Korsakoff syndrome had not resolved by six months.

Simultaneous chromatic and luminance human electroretinogram responses.

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Parry, Neil R A; Murray, Ian J; Panorgias, Athanasios; McKeefry, Declan J; Lee, Barry B; Kremers, Jan

2012-07-01

The parallel processing of information forms an important organisational principle of the primate visual system. Here we describe experiments which use a novel chromatic–achromatic temporal compound stimulus to simultaneously identify colour and luminance specific signals in the human electroretinogram (ERG). Luminance and chromatic components are separated in the stimulus; the luminance modulation has twice the temporal frequency of the chromatic modulation. ERGs were recorded from four trichromatic and two dichromatic subjects (1 deuteranope and 1 protanope). At isoluminance, the fundamental (first harmonic) response was elicited by the chromatic component in the stimulus. The trichromatic ERGs possessed low-pass temporal tuning characteristics, reflecting the activity of parvocellular post-receptoral mechanisms. There was very little first harmonic response in the dichromats' ERGs. The second harmonic response was elicited by the luminance modulation in the compound stimulus and showed, in all subjects, band-pass temporal tuning characteristic of magnocellular activity. Thus it is possible to concurrently elicit ERG responses from the human retina which reflect processing in both chromatic and luminance pathways. As well as providing a clear demonstration of the parallel nature of chromatic and luminance processing in the human retina, the differences that exist between ERGs from trichromatic and dichromatic subjects point to the existence of interactions between afferent post-receptoral pathways that are in operation from the earliest stages of visual processing.

SPITZER SAGE-SMC INFRARED PHOTOMETRY OF MASSIVE STARS IN THE SMALL MAGELLANIC CLOUD

International Nuclear Information System (INIS)

Bonanos, A. Z.; Lennon, D. J.; Massa, D. L.

2010-01-01

We present a catalog of 5324 massive stars in the Small Magellanic Cloud (SMC), with accurate spectral types compiled from the literature, and a photometric catalog for a subset of 3654 of these stars, with the goal of exploring their infrared properties. The photometric catalog consists of stars with infrared counterparts in the Spitzer SAGE-SMC survey database, for which we present uniform photometry from 0.3to24 μm in the UBVIJHK s +IRAC+MIPS24 bands. We compare the color-magnitude diagrams and color-color diagrams to those of stars in the Large Magellanic Cloud (LMC), finding that the brightest infrared sources in the SMC are also the red supergiants, supergiant B[e] (sgB[e]) stars, luminous blue variables, and Wolf-Rayet stars, with the latter exhibiting less infrared excess, the red supergiants being less dusty and the sgB[e] stars being on average less luminous. Among the objects detected at 24 μm in the SMC are a few very luminous hypergiants, four B-type stars with peculiar, flat spectral energy distributions, and all three known luminous blue variables. We detect a distinct Be star sequence, displaced to the red, and suggest a novel method of confirming Be star candidates photometrically. We find a higher fraction of Oe and Be stars among O and early-B stars in our SMC catalog, respectively, when compared to the LMC catalog, and that the SMC Be stars occur at higher luminosities. We estimate mass-loss rates for the red supergiants, confirming the correlation with luminosity even at the metallicity of the SMC. Finally, we confirm the new class of stars displaying composite A and F type spectra, the sgB[e] nature of 2dFS1804 and find the F0 supergiant 2dFS3528 to be a candidate luminous blue variable with cold dust.

Luminous Phenomena - A Scientific Investigation of Anomalous Luminous Atmospheric Phenomena

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Teodorani, M.

2003-12-01

Anomalous atmospheric luminous phenomena reoccur in several locations of Earth, in the form of multi-color light balls characterized by large dimensions, erratic motion, long duration and a correlated electromagnetic field. The author (an astrophysicist) of this book, which is organized as a selection of some of his technical and popularizing papers and seminars, describes and discusses all the efforts that have been done in 10 years, through several missions and a massive data analysis, in order to obtain some scientific explanation of this kind of anomalies, in particular the Hessdalen anomaly in Norway. The following topics are treated in the book: a) geographic archive of the areas of Earth where such phenomena are known to reoccur most often; b) observational techniques of astrophysical kind that have been used to acquire the data; c) main scientific results obtained so far; d) physical interpretation and natural hypothesis vs. ETV hypothesis; e) historical and chronological issues; f) the importance to brindle new energy sources; g) the importance to keep distance from any kind of "ufology". An unpublished chapter is entirely devoted to a detailed scientific investigation project of light phenomena reoccurring on the Ontario lake; the chosen new-generation multi-wavelength sensing instrumentation that is planned to be used in future missions in that specific area, is described together with scientific rationale and planned procedures. The main results, which were obtained in other areas of the world, such as the Arizona desert, USA and the Sibillini Mountains, Italy, are also briefly mentioned. One chapter is entirely dedicated to the presentation of extensive abstracts of technical papers by the author concerning this specific subject. The book is accompanied with a rich source of bibliographic references.

Massive binaries in the vicinity of Sgr A*

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Pfuhl, O.; Gillessen, S.; Genzel, R.; Eisenhauer, F.; Fritz, T. K.; Ott, T. [Max-Planck-Institut für Extraterrestrische Physik, D-85748 Garching (Germany); Alexander, T. [Faculty of Physics, Weizmann Institute of Science, P.O. Box 26, Rehovot 76100 (Israel); Martins, F., E-mail: pfuhl@mpe.mpg.de [LUPM, Université Montpelier 2, CNRS, Place Eugéne Bataillon, F-34095, Montpellier (France)

2014-02-20

A long-term spectroscopic and photometric survey of the most luminous and massive stars in the vicinity of the supermassive black hole Sgr A* revealed two new binaries: a long-period Ofpe/WN9 binary, IRS 16NE, with a modest eccentricity of 0.3 and a period of 224 days, and an eclipsing Wolf-Rayet binary with a period of 2.3 days. Together with the already identified binary IRS 16SW, there are now three confirmed OB/WR binaries in the inner 0.2 pc of the Galactic center. Using radial velocity change upper limits, we were able to constrain the spectroscopic binary fraction in the Galactic center to F{sub SB}=0.30{sub −0.21}{sup +0.34} at a confidence level of 95%, a massive binary fraction close to that observed in dense clusters. The fraction of eclipsing binaries with photometric amplitudes Δm > 0.4 is F{sub EB}{sup GC}=3%±2%, which is consistent with local OB star clusters (F {sub EB} = 1%). Overall, the Galactic center binary fraction seems to be similar to the binary fraction in comparable young clusters.

A Radio Study of the Ultra-luminous FIR Galaxy NGC 6240

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Colbert, E.; Wilson, A. S.; Bland-Hawthorn, J.

1993-05-01

A number of galaxies observed in the IRAS mission are noted to emit ~ 99% of their bolometric flux in the FIR, with FIR luminosities in excess of 10(11) Lsun. The interacting galaxy NGC 6240 has often been referred to as the ``proto-typical'' ultra-luminous (L_FIR >~ 10(12) Lsun) FIR galaxy. The origin of the FIR excess remains a disputed subject in the literature. New observations of NGC 6240 were taken with the VLA at 20cm in the B-configuration, and at 3.6cm in the A-configuration. No significant radio emission was detected from or near the possible ultra-massive ``dark core'' hypothesized by Bland-Hawthorn et. al. (1991); however, approximately 30% of Seyfert galaxies have 20 cm radio luminosities weaker than the upper limit derived from the radio maps. The non-thermal radio emission from luminous FIR galaxies is tightly correlated with the FIR emission. Previous radio observations of NGC 6240 revealed two compact, steep-spectrum nuclear sources, nearly coincident with the two nuclear sources seen in optical images. The 2 images from the new VLA observations and 5 images from previous VLA observations are used to identify the morphological and spectral features of the strong, compact components in the nuclear regions (~ 3 kpc) from the nucleus. Feasible explanations for the radio emission are discussed. The models that have been proposed in the literature for the FIR excess of NGC 6240 are evaluated for consistency with the observed radio emission.

Milliarcsecond Imaging of the Radio Emission from the Quasar with the Most Massive Black Hole at Reionization

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Wang, Ran; Wu, Xue-Bing; Jiang, Linhua [Kavli Institute of Astronomy and Astrophysics at Peking University, No. 5 Yiheyuan Road, Haidian District, Beijing 100871 (China); Momjian, Emmanuel; Carilli, Chris L. [National Radio Astronomy Observatory, P.O. Box 0, Socorro, NM 87801 (United States); Fan, Xiaohui [Steward Observatory, University of Arizona, 933 N Cherry Avenue, Tucson, AZ 85721 (United States); Walter, Fabian [Max-Planck-Institute for Astronomy, Königsstuhl 17, D-69117 Heidelberg (Germany); Strauss, Michael A. [Department of Astrophysical Sciences, Princeton University, Princeton, NJ 08544 (United States); Wang, Feige [Department of Astronomy, School of Physics, Peking University, No. 5 Yiheyuan Road, Haidian District, Beijing 100871 (China)

2017-02-01

We report Very Long Baseline Array (VLBA) observations of the 1.5 GHz radio continuum emission of the z = 6.326 quasar SDSS J010013.02+280225.8 (hereafter J0100+2802). J0100+2802 is by far the most optically luminous and is a radio-quiet quasar with the most massive black hole known at z > 6. The VLBA observations have a synthesized beam size of 12.10 mas ×5.36 mas (FWHM), and detected the radio continuum emission from this object with a peak surface brightness of 64.6 ± 9.0 μ Jy beam{sup −1} and a total flux density of 88 ± 19 μ Jy. The position of the radio peak is consistent with that from SDSS in the optical and Chandra in the X-ray. The radio source is marginally resolved by the VLBA observations. A 2D Gaussian fit to the image constrains the source size to (7.1 ± 3.5) mas × (3.1 ± 1.7) mas. This corresponds to a physical scale of (40 ± 20) pc × (18 ± 10) pc. We estimate the intrinsic brightness temperature of the VLBA source to be T {sub B} = (1.6 ± 1.2) × 10{sup 7} K. This is significantly higher than the maximum value in normal star-forming galaxies, indicating an active galactic nucleus (AGN) origin for the radio continuum emission. However, it is also significantly lower than the brightness temperatures found in highest-redshift radio-loud quasars. J0100+2802 provides a unique example for studying the radio activity in optically luminous and radio-quiet AGNs in the early universe. Further observations at multiple radio frequencies will accurately measure the spectral index and address the dominant radiation mechanism of the radio emission.

The uncultured luminous symbiont of Anomalops katoptron (Beryciformes: Anomalopidae) represents a new bacterial genus.

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Hendry, Tory A; Dunlap, Paul V

2011-12-01

Flashlight fishes (Beryciformes: Anomalopidae) harbor luminous symbiotic bacteria in subocular light organs and use the bacterial light for predator avoidance, feeding, and communication. Despite many attempts anomalopid symbionts have not been brought into laboratory culture, which has restricted progress in understanding their phylogenetic relationships with other luminous bacteria, identification of the genes of their luminescence system, as well as the nature of their symbiotic interactions with their fish hosts. To begin addressing these issues, we used culture-independent analysis of the bacteria symbiotic with the anomalopid fish, Anomalops katoptron, to characterize the phylogeny of the bacteria and to identify the genes of their luminescence system including those involved in the regulation of luminescence. Analysis of the 16S rRNA, atpA, gapA, gyrB, pyrH, recA, rpoA, and topA genes resolved the A. katoptron symbionts as a clade nested within and deeply divergent from other members of Vibrionaceae. The bacterial luminescence (lux) genes were identified as a contiguous set (luxCDABEG), as found for the lux operons of other luminous bacteria. Phylogenetic analysis based on the lux genes confirmed the housekeeping gene phylogenetic placement. Furthermore, genes flanking the lux operon in the A. katoptron symbionts differed from those flanking lux operons of other genera of luminous bacteria. We therefore propose the candidate name Candidatus Photodesmus (Greek: photo = light, desmus = servant) katoptron for the species of bacteria symbiotic with A. katoptron. Results of a preliminary genomic analysis for genes regulating luminescence in other bacteria identified only a Vibrio harveyi-type luxR gene. These results suggest that expression of the luminescence system might be continuous in P. katoptron. Copyright © 2011 Elsevier Inc. All rights reserved.

Robust brightness enhancement across a luminance range of the glare illusion.

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Tamura, Hideki; Nakauchi, Shigeki; Koida, Kowa

2016-01-01

The glare illusion refers to brightness enhancement and the perception of a self-luminous appearance that occurs when a central region is surrounded by a luminance gradient. The center region appears to be a light source, with its light dispersing into the surrounding region. If the luminous edge is critical for generating the illusion, modulating the perceived luminance of the image, and switching its appearance from luminous to nonluminous, would have a strong impact on lightness and brightness estimation. Here, we quantified the illusion in two ways, by assessing brightness enhancement and examining whether the center region appeared luminous. Thus, we could determine whether the two effects occurred jointly or independently. We examined a wide luminance range of center regions, from 0 to 200% relative to background. Brightness enhancement in the illusion was observed for a wide range of luminances (20% to 200% relative to background), while a luminous-white appearance was observed when the center region luminance was 145% of the background. These results exclude the possibility that brightness enhancement occurs because the stimuli appear self-luminous. We suggest that restoring the original image intensity precedes the perceptual process of lightness estimation.

Identification of Different Classes of Luminal Progenitor Cells within Prostate Tumors

Directory of Open Access Journals (Sweden)

Supreet Agarwal

2015-12-01

Full Text Available Primary prostate cancer almost always has a luminal phenotype. However, little is known about the stem/progenitor properties of transformed cells within tumors. Using the aggressive Pten/Tp53-null mouse model of prostate cancer, we show that two classes of luminal progenitors exist within a tumor. Not only did tumors contain previously described multipotent progenitors, but also a major population of committed luminal progenitors. Luminal cells, sorted directly from tumors or grown as organoids, initiated tumors of adenocarcinoma or multilineage histological phenotypes, which is consistent with luminal and multipotent differentiation potentials, respectively. Moreover, using organoids we show that the ability of luminal-committed progenitors to self-renew is a tumor-specific property, absent in benign luminal cells. Finally, a significant fraction of luminal progenitors survived in vivo castration. In all, these data reveal two luminal tumor populations with different stem/progenitor cell capacities, providing insight into prostate cancer cells that initiate tumors and can influence treatment response.

Luminance cues constrain chromatic blur discrimination in natural scene stimuli.

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Sharman, Rebecca J; McGraw, Paul V; Peirce, Jonathan W

2013-03-22

Introducing blur into the color components of a natural scene has very little effect on its percept, whereas blur introduced into the luminance component is very noticeable. Here we quantify the dominance of luminance information in blur detection and examine a number of potential causes. We show that the interaction between chromatic and luminance information is not explained by reduced acuity or spatial resolution limitations for chromatic cues, the effective contrast of the luminance cue, or chromatic and achromatic statistical regularities in the images. Regardless of the quality of chromatic information, the visual system gives primacy to luminance signals when determining edge location. In natural viewing, luminance information appears to be specialized for detecting object boundaries while chromatic information may be used to determine surface properties.

Spectro-polarimetric study of the early evolutionary phases of the most massive galaxies

International Nuclear Information System (INIS)

Vernet, Joel

2001-01-01

This research thesis addresses the study of the early phases of evolution of the most massive galaxies (giant elliptic), a fundamental process which is a matter of study for various reasons exposed by the author in his introduction. While presented results are based on spectro-polarimetric observations, the author first presents specific instruments and methods used by spectropolarimetry which provides access to variations of all vectorial properties of light, without loss of information. Then, he reports the study of a near powerful radio-galaxy, Cygnus A, the study of nine radio-galaxies with a high redshift, and the study of a far ultra-luminous infrared galaxy (SMM J02399-0136). Results are then discussed and perspectives of research are proposed. Appendices present the theoretical study of the contribution of massive stars to the diffuse extragalactic ionizing background, and observations made on a near radio-galaxy (NGC 6251)

The HR diagram for luminous stars in nearby galaxies

International Nuclear Information System (INIS)

Humphreys, R.M.

1978-01-01

Due to the extreme faintness of stars in other galaxies it is only possible to sample the brightest stars in the nearest galaxies. The observations must then be compared with comparable data for the brightest stars, the supergiants and O-type stars, in the Milky Way. The data for the luminous stars are most complete for the Milky Way and the Large Magellanic Cloud. The luminosities for the stars in our Galaxy are based on their membership in associations and clusters, and consequently are representative of Population I within approximately 3kpc of the Sun. The data for the stars in the LMC with spectral types O to G8 come from published observations, and the M supergiants are from the author's recent observations of red stars in the LMC. This is the first time that the M supergiants have been included in an HR diagram of the Large Cloud. The presence of the red stars is important for any discussion of the evolution of the massive stars. (Auth.)

Luminous bacteria cultured from fish guts in the Gulf of Oman.

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Makemson, J C; Hermosa, G V

1999-01-01

The incidence of culturable luminous bacteria in Omani market fish guts was correlated to habitat type amongst 109 species of fish. Isolated representative luminous bacteria were compared to known species using the Biolog system (95 traits/isolate) and cluster analysis, which showed that the main taxa present in fish guts were clades related to Vibrio harveyi and Photobacterium species with sporadic incidence of P. phosphoreum. The luminous isolates from gut of the slip-mouth (barred pony fish), Leiognathus fasciatus, were mainly a type related to Photobacterium but phenotypically different from known species. These luminous gut bacteria were identical with the bacteria in the light organ, indicating that the light organ supplies a significant quantity of luminous bacteria to the gut. In many of the fish that lack light organs, luminous bacteria were also the dominant bacterial type in the gut, while in some others luminous bacteria were encountered sporadically and at low densities, reflecting the incidence of culturable luminous bacteria in seawater. Pelagic fish contained the highest incidence of culturable luminous bacteria and reef-associated fish the lowest. No correlation was found between the incidence of culturable luminous bacteria and the degree to which fish produce a melanin-covered gut. Copyright 1999 John Wiley & Sons, Ltd.

VLTI-AMBER Velocity-Resolved Aperture-Synthesis Imaging of Eta Carinae with a Spectral Resolution of 12 000: Studies of the Primary Star Wind and Innermost Wind-Wind Collision Zone

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Weigelt, G.; Hofmann, K.-H.; Schertl, D.; Clementel, N.; Corcoran, M. F.; Damineli, A.; de Wit, W.-J.; Grellmann, R.; Groh, J.; Guieu, S.;

Revealing evolved massive stars with Spitzer

Science.gov (United States)

Gvaramadze, V. V.; Kniazev, A. Y.; Fabrika, S.

2010-06-01

Massive evolved stars lose a large fraction of their mass via copious stellar wind or instant outbursts. During certain evolutionary phases, they can be identified by the presence of their circumstellar nebulae. In this paper, we present the results of a search for compact nebulae (reminiscent of circumstellar nebulae around evolved massive stars) using archival 24-μm data obtained with the Multiband Imaging Photometer for Spitzer. We have discovered 115 nebulae, most of which bear a striking resemblance to the circumstellar nebulae associated with luminous blue variables (LBVs) and late WN-type (WNL) Wolf-Rayet (WR) stars in the Milky Way and the Large Magellanic Cloud (LMC). We interpret this similarity as an indication that the central stars of detected nebulae are either LBVs or related evolved massive stars. Our interpretation is supported by follow-up spectroscopy of two dozen of these central stars, most of which turn out to be either candidate LBVs (cLBVs), blue supergiants or WNL stars. We expect that the forthcoming spectroscopy of the remaining objects from our list, accompanied by the spectrophotometric monitoring of the already discovered cLBVs, will further increase the known population of Galactic LBVs. This, in turn, will have profound consequences for better understanding the LBV phenomenon and its role in the transition between hydrogen-burning O stars and helium-burning WR stars. We also report on the detection of an arc-like structure attached to the cLBV HD 326823 and an arc associated with the LBV R99 (HD 269445) in the LMC. Partially based on observations collected at the German-Spanish Astronomical Centre, Calar Alto, jointly operated by the Max-Planck-Institut für Astronomie Heidelberg and the Instituto de Astrofísica de Andalucía (CSIC). E-mail: vgvaram@mx.iki.rssi.ru (VVG); akniazev@saao.ac.za (AYK); fabrika@sao.ru (SF)

Relationship between luminous fish and symbiosis. I. Comparative studies of lipopolysaccharides isolated from symbiotic luminous bacteria of the luminous marine fish, Physiculus japonicus.

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Kuwae, T; Andoh, M; Fukasawa, S; Kurata, M

1983-01-01

In order to investigate the relationship between host and symbiosis in the luminous marine fish, Physiculus japonicus, the bacterial lipopolysaccharides (LPS) of symbiotic luminous bacteria were compared serologically and electrophoretically. Five symbiotic luminous bacteria (PJ strains) were separately isolated from five individuals of this fish species caught at three points, off the coasts of Chiba, Nakaminato, and Oharai. LPS preparations were made from these bacteria by Westphal's phenol-water method and highly purified by repeated ultracentrifugation. These LPSs contained little or no 2-keto-3-deoxyoctonate and had powerful mitogenic activity. In sodium dodecylsulfate polyacrylamide gel electrophoresis, these PJ-1 to -5 LPSs were separated by their electrophoretic patterns into three groups; the first group included PJ-1 and PJ-4, the second group PJ-2 and PJ-3, and the third group PJ-5 alone. The results agreed with those of the double immunodiffusion test; precipitin lines completely coalesced within each group but not with other groups. In immunoelectrophoresis, one precipitin line was observed between anti PJ-2 LPS serum and PJ-5 LPS but the electrophoretic mobility of PJ-5 LPS was clearly different from that of the PJ-2 LPS group. Furthermore, in a 50% inhibition test with PJ-2 LPS by the passive hemolysis system, the doses of PJ-2 LPS, PJ-3 LPS, and PJ-5 LPS required for 50% inhibition (ID50) in this system were 0.25, 0.25, and 21.6 micrograms/ml for each alkali-treated LPS, respectively, and the ID50's of both PJ-1 LPS and PJ-4 LPS were above 1,000 micrograms/ml. These results indicate that PJ-5 LPS has an antigenic determinant partially in common with LPS from the PJ-2 group but not with LPS from the PJ-1 group and that the symbiotic luminous bacterium PJ-5 is more closely related to the PJ-2 group than to the PJ-1 group. These results show that the species Physiculus japonicus is symbiotically associated with at least three immunologically different

Standard deviation of luminance distribution affects lightness and pupillary response.

Science.gov (United States)

Kanari, Kei; Kaneko, Hirohiko

2014-12-01

We examined whether the standard deviation (SD) of luminance distribution serves as information of illumination. We measured the lightness of a patch presented in the center of a scrambled-dot pattern while manipulating the SD of the luminance distribution. Results showed that lightness decreased as the SD of the surround stimulus increased. We also measured pupil diameter while viewing a similar stimulus. The pupil diameter decreased as the SD of luminance distribution of the stimuli increased. We confirmed that these results were not obtained because of the increase of the highest luminance in the stimulus. Furthermore, results of field measurements revealed a correlation between the SD of luminance distribution and illuminance in natural scenes. These results indicated that the visual system refers to the SD of the luminance distribution in the visual stimulus to estimate the scene illumination.

Tritium pollution in the Swiss luminous compound industry

International Nuclear Information System (INIS)

Krejci, K.; Zeller, Jr.

1979-01-01

The Swiss luminous compound industry is an important consumer of tritium. About 350kCi go into production of tritium gas-filled light sources and 40kCi into production of tritium luminous compound annually. To illustrate the pollution problem, a factory is mentioned that handles 200kCi annually and a chain of luminizers, processing 20kCi over the same period as tritium luminous compound. This material is manufactured by coating phosphors with tritiated polystyrene having a specific activity up to 200Ci/g. Because of the high specific activity, the radiation damage produces an average activity release of 5.2% annually, which is one of the main reasons for public and occupational exposure. The processing of large quantities of tritium gas requires special equipment, such as units made entirely of stainless steel for purification and hydrogenation, oxidation systems for highly contaminated air, glove boxes, ventilation and monitoring systems. Nevertheless, contamination of air, surfaces, water and workers cannot be avoided. Only in a few cases were MPC-values for tritium content in urine of workers exceeded. From these results, biological half-lives between 5-15 days were estimated. Regular medical examinations showed no significant influence in blood picture parameters, except in one single case with a tritium concentration in urine of 2.8mCi/litre. Entirely different problems arise in most luminizing factories where luminous paint is processed as an open radioactive source. (author)

Massive vulvar edema in a woman with preeclampsia: a case report.

Science.gov (United States)

Daponte, Alexandros; Skentou, Hara; Dimopoulos, Konstantinos D; Kallitsaris, Athanasios; Messinis, Ioannis E

2007-11-01

Massive vulvar edema in a woman with preeclampsia preceded the development of massive ascites and impending eclampsia. A 17-year-old preeclamptic, primiparous woman was admitted with preeclampsia and massive vulvar edema. Other causes were excluded. The vulvar edema increased as the blood pressure and ascites increased, and a severe headache developed. Cesarean section for increasing preclampsia was performed. In the puerperium, the blood pressure improved and vulvar edema resolved. The clinical picture of the vulvar edema correlated with the severity of the preeclampsia. The presence of vulvar edema in women with preeclampsia should indicate immediate admission to the hospital. These patients must be considered as at high risk, and close monitoring must be instituted. In our case, vulvar edema preceded massive ascites development. We assume a common development mechanism for these signs in preeclampsia, due mainly to increased capillary permeability and hypoalbuminemia. The attending physician must be prepared for immediate delivery and possible preeclampsia complications in these patients.

Massive Star Burps, Then Explodes

Science.gov (United States)

2007-04-01

event was a complete surprise," added Alex Filippenko, leader of the UC Berkeley/Keck supernova group and a member of NASA'S Swift team. "It opens up a fascinating new window on how some kinds of stars die." All the observations suggest that the supernova's blast wave took only a few weeks to reach the shell of material ejected two years earlier, which did not have time to drift very far from the star. As the wave smashed into the ejecta, it heated the gas to millions of degrees, hot enough to emit copious X-rays. The Swift satellite saw the supernova continue to brighten in X-rays for 100 days, something that has never been seen before in a supernova. All supernovae previously observed in X-rays have started off bright and then quickly faded to invisibility. "You don't need a lot of mass in the ejecta to produce a lot of X-rays," notes Immler. Swift's ability to monitor the supernova's X-ray rise and decline over six months was crucial to his team's mass determination. But he adds that Chandra's sharp resolution enabled his group to resolve the supernova from a bright X-ray source that appears in the field of view of Swift's X-ray Telescope. "We could not have made this measurement without Chandra," says Immler, who will submit his team's paper next week to the Astrophysical Journal. "The synergy between Swift's fast response and its ability to observe a supernova every day for a long period, and Chandra's high spatial resolution, is leading to a lot of interesting results." Foley and his colleagues, whose paper appears in the March 10 Astrophysical Journal Letters, propose that the star recently transitioned from a Luminous Blue Variable (LBV) star to a Wolf-Rayet star. An LBV is a massive star in a brief but unstable phase of stellar evolution. Similar to the 2004 eruption, LBVs are prone to blow off large amounts of mass in outbursts so extreme that they are frequently mistaken for supernovae, events dubbed "supernova impostors." Wolf-Rayet stars are hot, highly

The role of luminance and chromatic cues in emmetropisation.

Science.gov (United States)

Rucker, Frances J

2013-05-01

At birth most, but not all eyes, are hyperopic. Over the course of the first few years of life the refraction gradually becomes close to zero through a process called emmetropisation. This process is not thought to require accommodation, though a lag of accommodation has been implicated in myopia development, suggesting that the accuracy of accommodation is an important factor. This review will cover research on accommodation and emmetropisation that relates to the ability of the eye to use colour and luminance cues to guide the responses. There are three ways in which changes in luminance and colour contrast could provide cues: (1) The eye could maximize luminance contrast. Monochromatic light experiments have shown that the human eye can accommodate and animal eyes can emmetropise using changes in luminance contrast alone. However, by reducing the effectiveness of luminance cues in monochromatic and white light by introducing astigmatism, or by reducing light intensity, investigators have revealed that the eye also uses colour cues in emmetropisation. (2) The eye could compare relative cone contrast to derive the sign of defocus information from colour cues. Experiments involving simulations of the retinal image with defocus have shown that relative cone contrast can provide colour cues for defocus in accommodation and emmetropisation. In the myopic simulation the contrast of the red component of a sinusoidal grating was higher than that of the green and blue component and this caused relaxation of accommodation and reduced eye growth. In the hyperopic simulation the contrast of the blue component was higher than that of the green and red components and this caused increased accommodation and increased eye growth. (3) The eye could compare the change in luminance and colour contrast as the eye changes focus. An experiment has shown that changes in colour or luminance contrast can provide cues for defocus in emmetropisation. When the eye is exposed to colour

The effect of chromatic and luminance information on reaction times.

Science.gov (United States)

O'Donell, Beatriz M; Barraza, Jose F; Colombo, Elisa M

2010-07-01

We present a series of experiments exploring the effect of chromaticity on reaction time (RT) for a variety of stimulus conditions, including chromatic and luminance contrast, luminance, and size. The chromaticity of these stimuli was varied along a series of vectors in color space that included the two chromatic-opponent-cone axes, a red-green (L-M) axis and a blue-yellow [S - (L + M)] axis, and intermediate noncardinal orientations, as well as the luminance axis (L + M). For Weber luminance contrasts above 10-20%, RTs tend to the same asymptote, irrespective of chromatic direction. At lower luminance contrast, the addition of chromatic information shortens the RT. RTs are strongly influenced by stimulus size when the chromatic stimulus is modulated along the [S - (L + M)] pathway and by stimulus size and adaptation luminance for the (L-M) pathway. RTs are independent of stimulus size for stimuli larger than 0.5 deg. Data are modeled with a modified version of Pieron's formula with an exponent close to 2, in which the stimulus intensity term is replaced by a factor that considers the relative effects of chromatic and achromatic information, as indexed by the RMS (square-root of the cone contrast) value at isoluminance and the Weber luminance contrast, respectively. The parameters of the model reveal how RT is linked to stimulus size, chromatic channels, and adaptation luminance and how they can be interpreted in terms of two chromatic mechanisms. This equation predicts that, for isoluminance, RTs for a stimulus lying on the S-cone pathway are higher than those for a stimulus lying on the L-M-cone pathway, for a given RMS cone contrast. The equation also predicts an asymptotic trend to the RT for an achromatic stimulus when the luminance contrast is sufficiently large.

Cosmological stability bound in massive gravity and bigravity

International Nuclear Information System (INIS)

Fasiello, Matteo; Tolley, Andrew J.

2013-01-01

We give a simple derivation of a cosmological bound on the graviton mass for spatially flat FRW solutions in massive gravity with an FRW reference metric and for bigravity theories. This bound comes from the requirement that the kinetic term of the helicity zero mode of the graviton is positive definite. The bound is dependent only on the parameters in the massive gravity potential and the Hubble expansion rate for the two metrics. We derive the decoupling limit of bigravity and FRW massive gravity, and use this to give an independent derivation of the cosmological bound. We recover our previous results that the tension between satisfying the Friedmann equation and the cosmological bound is sufficient to rule out all observationally relevant FRW solutions for massive gravity with an FRW reference metric. In contrast, in bigravity this tension is resolved due to different nature of the Vainshtein mechanism. We find that in bigravity theories there exists an FRW solution with late-time self-acceleration for which the kinetic terms for the helicity-2, helicity-1 and helicity-0 are generically nonzero and positive making this a compelling candidate for a model of cosmic acceleration. We confirm that the generalized bound is saturated for the candidate partially massless (bi)gravity theories but the existence of helicity-1/helicity-0 interactions implies the absence of the conjectured partially massless symmetry for both massive gravity and bigravity

Month-hour distributions of zenith luminance and diffuse illuminance in Madrid

International Nuclear Information System (INIS)

Soler, Alfonso; Gopinathan, Kannam K.; Robledo, Luis; Ruiz, Enrique

2004-01-01

Month-hour equal mean zenith luminance contours are obtained from one year of data of zenith luminance measurements for cloudless, overcast and partly cloudy skies and also when the combined data for all sky types are considered. For many hours in different months, the overcast sky luminance values are roughly about three times the cloudless sky luminance values and one and a half times the partly cloudy sky values. The dependence of month-hour equal mean zenith luminance contours on the ratio of global to extraterrestrial illuminance on a horizontal surface is also given. From equal mean zenith luminance contours, the approximate values of the mean zenith luminance for different sky conditions and different hours and months of the year can be easily obtained. Month-hour equal mean diffuse illuminance contours are obtained from diffuse illuminance measurements performed during the period 1992-1998. The dependence on solar altitude of the monthly average hourly values of diffuse illuminance is given and compared to the corresponding one obtained from data for Bet Dagan (Israel)

Effects of Irradiation on bacterial atp luminous intensity of cooled pork and chicken

International Nuclear Information System (INIS)

Ju Hua

2010-01-01

The effect of irradiation on cooled pork and chicken was detected with ATP luminous intensity method. The influences of other factors to ATP luminous intensity were also discussed. There was positive correlation between ATP standard concentration and ATP luminous intensity, and negative correlation between irradiation dosage and ATP luminous intensity. The trend of ATP luminous intensity of cooled pork and chicken after irradiation was inverse S, and the maximum ATP luminous intensity appeared at 6.0 kGy, and minimum at 4.0 and 8.0 kGy. Sterilized water and sterilized pork had no interference to ATP luminous intensity of the samples. There was significant positive correlation between E. coli 10003 concentration and ATP luminous intensity, the coefficient correlation was 0.9437. (authors)

Luminance-based specular gloss characterization.

Science.gov (United States)

Leloup, Frédéric B; Pointer, Michael R; Dutré, Philip; Hanselaer, Peter

2011-06-01

Gloss is a feature of visual appearance that arises from the directionally selective reflection of light incident on a surface. Especially when a distinct reflected image is perceptible, the luminance distribution of the illumination scene above the sample can strongly influence the gloss perception. For this reason, industrial glossmeters do not provide a satisfactory gloss estimation of high-gloss surfaces. In this study, the influence of the conditions of illumination on specular gloss perception was examined through a magnitude estimation experiment in which 10 observers took part. A light booth with two light sources was utilized: the mirror image of only one source being visible in reflection by the observer. The luminance of both the reflected image and the adjacent sample surface could be independently varied by separate adjustment of the intensity of the two light sources. A psychophysical scaling function was derived, relating the visual gloss estimations to the measured luminance of both the reflected image and the off-specular sample background. The generalization error of the model was estimated through a validation experiment performed by 10 other observers. In result, a metric including both surface and illumination properties is provided. Based on this metric, improved gloss evaluation methods and instruments could be developed.

Detection of chromatic and luminance distortions in natural scenes.

Science.gov (United States)

Jennings, Ben J; Wang, Karen; Menzies, Samantha; Kingdom, Frederick A A

2015-09-01

A number of studies have measured visual thresholds for detecting spatial distortions applied to images of natural scenes. In one study, Bex [J. Vis.10(2), 1 (2010)10.1167/10.2.231534-7362] measured sensitivity to sinusoidal spatial modulations of image scale. Here, we measure sensitivity to sinusoidal scale distortions applied to the chromatic, luminance, or both layers of natural scene images. We first established that sensitivity does not depend on whether the undistorted comparison image was of the same or of a different scene. Next, we found that, when the luminance but not chromatic layer was distorted, performance was the same regardless of whether the chromatic layer was present, absent, or phase-scrambled; in other words, the chromatic layer, in whatever form, did not affect sensitivity to the luminance layer distortion. However, when the chromatic layer was distorted, sensitivity was higher when the luminance layer was intact compared to when absent or phase-scrambled. These detection threshold results complement the appearance of periodic distortions of the image scale: when the luminance layer is distorted visibly, the scene appears distorted, but when the chromatic layer is distorted visibly, there is little apparent scene distortion. We conclude that (a) observers have a built-in sense of how a normal image of a natural scene should appear, and (b) the detection of distortion in, as well as the apparent distortion of, natural scene images is mediated predominantly by the luminance layer and not chromatic layer.

Luminous vibriosis in rock lobster Jasus verreauxi (Decapoda: Palinuridae) phyllosoma larvae associated with infection by Vibrio harveyi.

Science.gov (United States)

Diggles, B K; Moss, G A; Carson, J; Anderson, C D

2000-11-14

Studies were conducted to determine the cause of outbreaks of luminous vibriosis in phyllosoma larvae of the packhorse rock lobster Jasus verreauxi reared in an experimental culture facility. On 2 separate occasions mortalities of up to 75% over a period of 4 wk were observed in 4th to 5th and 8th to 10th instar phyllosomas at water temperatures of 20 and 23 degrees C, respectively. Affected larvae became opaque, exhibited small red spots throughout the body and pereiopods, and were faintly luminous when viewed in the dark. Histopathology showed that the gut and hepatopancreas tubules of moribund phyllosomas contained massive bacterial plaques. The hepatopancreas tubules of moribund larvae were atrophic and some contained necrotic cells sloughed into the lumen. Dense, pure cultures of a bacterium identified as Vibrio harveyi were isolated from moribund larvae. The disease syndrome was reproduced by in vivo challenge and V. harveyi was successfully reisolated from diseased larvae after apparently healthy larvae were exposed by immersion to baths of more than 10(4) V. harveyi ml(-1) at 24 degrees C. Injured larvae were more susceptible to infection than were healthy larvae. Survival of larvae experimentally and naturally exposed to V. harveyi was improved when antibiotics were administered via bath exposures.

Application of radioisotope for radio-luminous watch and clock industry in Japan

International Nuclear Information System (INIS)

Murayama, Yoshihiko

1981-01-01

In 1979, Japan became No. 1 watch and clock production country in the world, and has produced 88 million watches and 59 million clocks in 1980. About 65% of them were exported. The production of radio-luminous watches and clocks in 1980 was estimated as 13 million and 11 million, respectively, and has increased by 40% as compared with the previous year. In Japan, the law concerning the prevention of radiation injuries due to radioisotopes and others is applied to radio-luminous watches and clocks, because radioactive substances are contained in luminous paint, and the production is regulated by the law as unsealed RI-using establishments. The permitted establishments engaging in radio-luminous watches and clocks are 3 luminous paint makers, 9 painting works and 35 watch and clock assembling plants. The RI utilized for radio-luminous watches and clocks is limited to Pm-147 at present, and 3788 Ci was used in 1980. About 70 years have elapsed since luminous paint was used for watches and clocks for the first time. The ISO instituted the international standard on radio-luminous paint for watches and clocks in 1975. The beta-ray emitted by Pm-147 is shielded perfectly by glasses and cases, and only the dose of brems-strahlung X-ray is the problem. The radiation control in radio-luminous watch and clock plants is described. (Kako, I.)

Closing the mind's eye: incoming luminance signals disrupt visual imagery.

Directory of Open Access Journals (Sweden)

Rachel Sherwood

Full Text Available Mental imagery has been associated with many cognitive functions, both high and low-level. Despite recent scientific advances, the contextual and environmental conditions that most affect the mechanisms of visual imagery remain unclear. It has been previously shown that the greater the level of background luminance the weaker the effect of imagery on subsequent perception. However, in these experiments it was unclear whether the luminance was affecting imagery generation or storage of a memory trace. Here, we report that background luminance can attenuate both mental imagery generation and imagery storage during an unrelated cognitive task. However, imagery generation was more sensitive to the degree of luminance. In addition, we show that these findings were not due to differential dark adaptation. These results suggest that afferent visual signals can interfere with both the formation and priming-memory effects associated with visual imagery. It follows that background luminance may be a valuable tool for investigating imagery and its role in various cognitive and sensory processes.

Impact of Intestinal Microbiota on Intestinal Luminal Metabolome

Science.gov (United States)

Matsumoto, Mitsuharu; Kibe, Ryoko; Ooga, Takushi; Aiba, Yuji; Kurihara, Shin; Sawaki, Emiko; Koga, Yasuhiro; Benno, Yoshimi

2012-01-01

Low–molecular-weight metabolites produced by intestinal microbiota play a direct role in health and disease. In this study, we analyzed the colonic luminal metabolome using capillary electrophoresis mass spectrometry with time-of-flight (CE-TOFMS) —a novel technique for analyzing and differentially displaying metabolic profiles— in order to clarify the metabolite profiles in the intestinal lumen. CE-TOFMS identified 179 metabolites from the colonic luminal metabolome and 48 metabolites were present in significantly higher concentrations and/or incidence in the germ-free (GF) mice than in the Ex-GF mice (p metabolome and a comprehensive understanding of intestinal luminal metabolome is critical for clarifying host-intestinal bacterial interactions. PMID:22724057

MN48: a new Galactic bona fide luminous blue variable revealed by Spitzer and SALT

Science.gov (United States)

Kniazev, A. Y.; Gvaramadze, V. V.; Berdnikov, L. N.

2016-07-01

In this paper, we report the results of spectroscopic and photometric observations of the candidate evolved massive star MN48 disclosed via detection of a mid-infrared circular shell around it with the Spitzer Space Telescope. Follow-up optical spectroscopy of MN48 with the Southern African Large Telescope (SALT) carried out in 2011-2015 revealed significant changes in the spectrum of this star, which are typical of luminous blue variables (LBVs). The LBV status of MN48 was further supported by photometric monitoring which shows that in 2009-2011 this star has brightened by ≈0.9 and 1 mag in the V and Ic bands, respectively, then faded by ≈1.1 and 1.6 mag during the next four years, and apparently started to brighten again recently. The detected changes in the spectrum and brightness of MN48 make this star the 18th known Galactic bona fide LBV and increase the percentage of LBVs associated with circumstellar nebulae to more than 70 per cent. We discuss the possible birth place of MN48 and suggest that this star might have been ejected either from a putative star cluster embedded in the H II region IRAS 16455-4531 or the young massive star cluster Westerlund 1.

SOUTHERN MASSIVE STARS AT HIGH ANGULAR RESOLUTION: OBSERVATIONAL CAMPAIGN AND COMPANION DETECTION

Energy Technology Data Exchange (ETDEWEB)

Sana, H. [European Space Agency/Space Telescope Science Institute, 3700 San Martin Drive, Baltimore, MD 21218 (United States); Le Bouquin, J.-B.; Duvert, G.; Zins, G. [Université Grenoble Alpes, IPAG, F-38000 Grenoble (France); Lacour, S.; Gauchet, L.; Pickel, D. [LESIA, Observatoire de Paris, CNRS, UPMC, Université Paris-Diderot, Paris Sciences et Lettres, 5 Place Jules Janssen, F-92195 Meudon (France); Berger, J.-P. [European Southern Observatory, Schwarzschild-Str. 2, D-85748 Garching bei München (Germany); Norris, B. [Sydney Institute for Astronomy, School of Physics, University of Sydney, NSW 2006 (Australia); Olofsson, J. [Max-Planck-Institut für Astronomie, Koenigstuhl 17, D-69117 Heidelberg (Germany); Absil, O. [Département d' Astrophysique, Géophysique et Océanographie, Université de Liège, 17 Allée du Six Août, B-4000 Liège (Belgium); De Koter, A. [Astrophysical Institute Anton Pannekoek, Universiteit van Amsterdam, Science Park 904, 1098XH Amsterdam (Netherlands); Kratter, K. [JILA, 440 UCB, University of Colorado, Boulder, CO 80309-0440 (United States); Schnurr, O. [Leibniz-Institut für Astrophysik Potsdam, An der Sternwarte 16, D-14482 Potsdam (Germany); Zinnecker, H., E-mail: hsana@stsci.edu [Deutsches SOFIA Instituut, SOFIA Science Center, NASA Ames Research Center, Mail Stop N232-12, Moffett Field, CA 94035 (United States)

2014-11-01

Multiplicity is one of the most fundamental observable properties of massive O-type stars and offers a promising way to discriminate between massive star formation theories. Nevertheless, companions at separations between 1 and 100 milliarcsec (mas) remain mostly unknown due to intrinsic observational limitations. At a typical distance of 2 kpc, this corresponds to projected physical separations of 2-200 AU. The Southern MAssive Stars at High angular resolution survey (SMaSH+) was designed to fill this gap by providing the first systematic interferometric survey of Galactic massive stars. We observed 117 O-type stars with VLTI/PIONIER and 162 O-type stars with NACO/Sparse Aperture Masking (SAM), probing the separation ranges 1-45 and 30-250 mas and brightness contrasts of ΔH < 4 and ΔH < 5, respectively. Taking advantage of NACO's field of view, we further uniformly searched for visual companions in an 8'' radius down to ΔH = 8. This paper describes observations and data analysis, reports the discovery of almost 200 new companions in the separation range from 1 mas to 8'' and presents a catalog of detections, including the first resolved measurements of over a dozen known long-period spectroscopic binaries. Excluding known runaway stars for which no companions are detected, 96 objects in our main sample (δ < 0°; H < 7.5) were observed both with PIONIER and NACO/SAM. The fraction of these stars with at least one resolved companion within 200 mas is 0.53. Accounting for known but unresolved spectroscopic or eclipsing companions, the multiplicity fraction at separation ρ < 8'' increases to f {sub m} = 0.91 ± 0.03. The fraction of luminosity class V stars that have a bound companion reaches 100% at 30 mas while their average number of physically connected companions within 8'' is f {sub c} = 2.2 ± 0.3. This demonstrates that massive stars form nearly exclusively in multiple systems. The nine non-thermal radio

Advancing Our Understanding of the Etiologies and Mutational Landscapes of Basal Like, Luminal A, and Luminal B Breast Cancers

Science.gov (United States)

2016-10-01

will be further analyzed for effects on reading frame and protein structure and function using analysis and prediction tools such as PolyPhen and...luminal A, and luminal B tumors. Originally this study intended to include 900 newly diagnosed first primary triple negative (TN) invasive breast cancer...breast cancer risk factors. At the end of the interview participants will be asked to donate an oral tissue specimen for future genetic testing. Medical

Influence of Al{sub 2}O{sub 3} reflective layer under phosphor layer on luminance and luminous efficiency characteristics in alternating-current plasma display panel

Energy Technology Data Exchange (ETDEWEB)

Park, Choon-Sang [School of Electronics Engineering, College of IT Engineering, Kyungpook National University, Daegu (Korea, Republic of); Tae, Heung-Sik, E-mail: hstae@ee.knu.ac.kr [School of Electronics Engineering, College of IT Engineering, Kyungpook National University, Daegu (Korea, Republic of); Jung, Eun Young [Core Technology Lab., Corporate R and D Center, Samsung SDI Company Ltd., Cheonan (Korea, Republic of)

2013-11-29

This paper examines the optical and discharge characteristics of alternating-current plasma display panel when adopting the Al{sub 2}O{sub 3} reflective layer. The Al{sub 2}O{sub 3} reflective layer is deposited under the phosphor layer by using the screen-printing method. The resulting changes in the optical and discharge characteristics, including the power consumption, color temperature, luminance, luminous efficiency, scanning electron microscopy image, and reflectance, are then compared for both cases with and without Al{sub 2}O{sub 3} reflective layer. As a result of optimizing the thicknesses between the Al{sub 2}O{sub 3} and phosphor layers, the luminance and luminous efficiency are improved by about 17% and 7%, respectively. - Highlights: • We examine characteristics of plasma display panel when adopting reflective layer. • Al{sub 2}O{sub 3} reflective layer was deposited under the phosphor layer. • Al{sub 2}O{sub 3} reflective layer with flaky shape is very effective in enhancing luminance.

Dynamics of backlight luminance for using smartphone in dark environment

Science.gov (United States)

Na, Nooree; Jang, Jiho; Suk, Hyeon-Jeong

2014-02-01

This study developed dynamic backlight luminance, which gradually changes as time passes for comfortable use of a smartphone display in a dark environment. The study was carried out in two stages. In the first stage, a user test was conducted to identify the optimal luminance by assessing the facial squint level, subjective glare evaluation, eye blink frequency and users' subjective preferences. Based on the results of the user test, the dynamics of backlight luminance was designed. It has two levels of luminance: the optimal level for initial viewing to avoid sudden glare or fatigue to users' eyes, and the optimal level for constant viewing, which is comfortable, but also bright enough for constant reading of the displayed material. The luminance for initial viewing starts from 10 cd/m2, and it gradually increases to 40 cd/m2 for users' visual comfort at constant viewing for 20 seconds; In the second stage, a validation test on dynamics of backlight luminance was conducted to verify the effectiveness of the developed dynamics. It involving users' subjective preferences, eye blink frequency, and brainwave analysis using the electroencephalogram (EEG) to confirm that the proposed dynamic backlighting enhances users' visual comfort and visual cognition, particularly for using smartphones in a dark environment.

Predicting daylight illuminance on inclined surfaces using sky luminance data

Energy Technology Data Exchange (ETDEWEB)

Li, D.H.W.; Lau, C.C.S.; Lam, J.C. [City University of Hong Kong, Kowloon (China). Dept. of Building and Construction

2005-07-01

Daylight illuminance, particularly on vertical surfaces, plays a major role in determining and evaluating the daylighting performance of a building. In many parts of the world, however, the basic daylight illuminance data for various vertical planes are not always readily available. The usual method to obtain diffuse illuminance on tilted planes would be based on inclined surface models using data from the horizontal measurements. Alternatively, the diffuse illuminance on a sloping plane can be computed by integrating the luminance distribution of the sky 'seen' by the plane. This paper presents an approach to estimate the vertical outdoor illuminance from sky luminance data and solar geometry. Sky luminance data recorded from January 1999 to December 2001 in Hong Kong and generated by two well-known sky luminance models (Kittler and Perez) were used to compute the outdoor illuminance for the four principal vertical planes (N, E, S and W). The performance of this approach was evaluated against data measured in the same period. Statistical analysis indicated that using sky luminance distributions to predict outdoor illuminance can give reasonably good agreement with measured data for all vertical surfaces. The findings provide an accurate alternative to determine the amount of daylight on vertical as well as other inclined surfaces when sky luminance data are available. (author)

High molecular gas fractions in normal massive star-forming galaxies in the young Universe.

Science.gov (United States)

Tacconi, L J; Genzel, R; Neri, R; Cox, P; Cooper, M C; Shapiro, K; Bolatto, A; Bouché, N; Bournaud, F; Burkert, A; Combes, F; Comerford, J; Davis, M; Schreiber, N M Förster; Garcia-Burillo, S; Gracia-Carpio, J; Lutz, D; Naab, T; Omont, A; Shapley, A; Sternberg, A; Weiner, B

2010-02-11

Stars form from cold molecular interstellar gas. As this is relatively rare in the local Universe, galaxies like the Milky Way form only a few new stars per year. Typical massive galaxies in the distant Universe formed stars an order of magnitude more rapidly. Unless star formation was significantly more efficient, this difference suggests that young galaxies were much more molecular-gas rich. Molecular gas observations in the distant Universe have so far largely been restricted to very luminous, rare objects, including mergers and quasars, and accordingly we do not yet have a clear idea about the gas content of more normal (albeit massive) galaxies. Here we report the results of a survey of molecular gas in samples of typical massive-star-forming galaxies at mean redshifts of about 1.2 and 2.3, when the Universe was respectively 40% and 24% of its current age. Our measurements reveal that distant star forming galaxies were indeed gas rich, and that the star formation efficiency is not strongly dependent on cosmic epoch. The average fraction of cold gas relative to total galaxy baryonic mass at z = 2.3 and z = 1.2 is respectively about 44% and 34%, three to ten times higher than in today's massive spiral galaxies. The slow decrease between z approximately 2 and z approximately 1 probably requires a mechanism of semi-continuous replenishment of fresh gas to the young galaxies.

Signs of depth-luminance covariance in 3-D cluttered scenes.

Science.gov (United States)

Scaccia, Milena; Langer, Michael S

2018-03-01

In three-dimensional (3-D) cluttered scenes such as foliage, deeper surfaces often are more shadowed and hence darker, and so depth and luminance often have negative covariance. We examined whether the sign of depth-luminance covariance plays a role in depth perception in 3-D clutter. We compared scenes rendered with negative and positive depth-luminance covariance where positive covariance means that deeper surfaces are brighter and negative covariance means deeper surfaces are darker. For each scene, the sign of the depth-luminance covariance was given by occlusion cues. We tested whether subjects could use this sign information to judge the depth order of two target surfaces embedded in 3-D clutter. The clutter consisted of distractor surfaces that were randomly distributed in a 3-D volume. We tested three independent variables: the sign of the depth-luminance covariance, the colors of the targets and distractors, and the background luminance. An analysis of variance showed two main effects: Subjects performed better when the deeper surfaces were darker and when the color of the target surfaces was the same as the color of the distractors. There was also a strong interaction: Subjects performed better under a negative depth-luminance covariance condition when targets and distractors had different colors than when they had the same color. Our results are consistent with a "dark means deep" rule, but the use of this rule depends on the similarity between the color of the targets and color of the 3-D clutter.

Stochastic and Resolvable Gravitational Waves from Ultralight Bosons.

Science.gov (United States)

Brito, Richard; Ghosh, Shrobana; Barausse, Enrico; Berti, Emanuele; Cardoso, Vitor; Dvorkin, Irina; Klein, Antoine; Pani, Paolo

2017-09-29

Ultralight scalar fields around spinning black holes can trigger superradiant instabilities, forming a long-lived bosonic condensate outside the horizon. We use numerical solutions of the perturbed field equations and astrophysical models of massive and stellar-mass black hole populations to compute, for the first time, the stochastic gravitational-wave background from these sources. In optimistic scenarios the background is observable by Advanced LIGO and LISA for field masses m_{s} in the range ∼[2×10^{-13},10^{-12}] and ∼5×[10^{-19},10^{-16}]  eV, respectively, and it can affect the detectability of resolvable sources. Our estimates suggest that an analysis of the stochastic background limits from LIGO O1 might already be used to marginally exclude axions with mass ∼10^{-12.5}  eV. Semicoherent searches with Advanced LIGO (LISA) should detect ∼15(5) to 200(40) resolvable sources for scalar field masses 3×10^{-13} (10^{-17})  eV. LISA measurements of massive BH spins could either rule out bosons in the range ∼[10^{-18},2×10^{-13}]  eV, or measure m_{s} with 10% accuracy in the range ∼[10^{-17},10^{-13}]  eV.

File list: His.Brs.10.AllAg.Luminal_cells [Chip-atlas[Archive

Lifescience Database Archive (English)

Full Text Available His.Brs.10.AllAg.Luminal_cells mm9 Histone Breast Luminal cells SRX213395,SRX213418...,SRX213416 http://dbarchive.biosciencedbc.jp/kyushu-u/mm9/assembled/His.Brs.10.AllAg.Luminal_cells.bed ...

File list: His.Brs.05.AllAg.Luminal_cells [Chip-atlas[Archive

Lifescience Database Archive (English)

Full Text Available His.Brs.05.AllAg.Luminal_cells mm9 Histone Breast Luminal cells SRX213395,SRX213418...,SRX213416 http://dbarchive.biosciencedbc.jp/kyushu-u/mm9/assembled/His.Brs.05.AllAg.Luminal_cells.bed ...

File list: His.Brs.50.AllAg.Luminal_cells [Chip-atlas[Archive

Lifescience Database Archive (English)

Full Text Available His.Brs.50.AllAg.Luminal_cells mm9 Histone Breast Luminal cells SRX213395,SRX213418...,SRX213416 http://dbarchive.biosciencedbc.jp/kyushu-u/mm9/assembled/His.Brs.50.AllAg.Luminal_cells.bed ...

Radiation exposure to dial painters from 3H luminous paint industry

International Nuclear Information System (INIS)

Sawant, J.V.

1992-01-01

Tritium is used as the active component in self-luminous paint. The paper describes in-vitro solubilisation study of luminous paint in blood serum. Besides urine samples of luminous paint workers and air samples of two watch factories were analysed for 3 H. The results of these analysis are also presented. (author). 8 refs., 4 figs., 4 tabs

File list: ALL.Brs.10.AllAg.Luminal_cells [Chip-atlas[Archive

Lifescience Database Archive (English)

Full Text Available ALL.Brs.10.AllAg.Luminal_cells mm9 All antigens Breast Luminal cells SRX213395,SRX2...13418,SRX213398,SRX213416 http://dbarchive.biosciencedbc.jp/kyushu-u/mm9/assembled/ALL.Brs.10.AllAg.Luminal_cells.bed ...

File list: ALL.Brs.50.AllAg.Luminal_cells [Chip-atlas[Archive

Lifescience Database Archive (English)

Full Text Available ALL.Brs.50.AllAg.Luminal_cells mm9 All antigens Breast Luminal cells SRX213395,SRX2...13418,SRX213398,SRX213416 http://dbarchive.biosciencedbc.jp/kyushu-u/mm9/assembled/ALL.Brs.50.AllAg.Luminal_cells.bed ...

File list: ALL.Brs.20.AllAg.Luminal_cells [Chip-atlas[Archive

Lifescience Database Archive (English)

Full Text Available ALL.Brs.20.AllAg.Luminal_cells mm9 All antigens Breast Luminal cells SRX213395,SRX2...13418,SRX213398,SRX213416 http://dbarchive.biosciencedbc.jp/kyushu-u/mm9/assembled/ALL.Brs.20.AllAg.Luminal_cells.bed ...

Astronomy. ASASSN-15lh: A highly super-luminous supernova.

Science.gov (United States)

Dong, Subo; Shappee, B J; Prieto, J L; Jha, S W; Stanek, K Z; Holoien, T W-S; Kochanek, C S; Thompson, T A; Morrell, N; Thompson, I B; Basu, U; Beacom, J F; Bersier, D; Brimacombe, J; Brown, J S; Bufano, F; Chen, Ping; Conseil, E; Danilet, A B; Falco, E; Grupe, D; Kiyota, S; Masi, G; Nicholls, B; Olivares E, F; Pignata, G; Pojmanski, G; Simonian, G V; Szczygiel, D M; Woźniak, P R

2016-01-15

We report the discovery of ASASSN-15lh (SN 2015L), which we interpret as the most luminous supernova yet found. At redshift z = 0.2326, ASASSN-15lh reached an absolute magnitude of Mu ,AB = -23.5 ± 0.1 and bolometric luminosity Lbol = (2.2 ± 0.2) × 10(45) ergs s(-1), which is more than twice as luminous as any previously known supernova. It has several major features characteristic of the hydrogen-poor super-luminous supernovae (SLSNe-I), whose energy sources and progenitors are currently poorly understood. In contrast to most previously known SLSNe-I that reside in star-forming dwarf galaxies, ASASSN-15lh appears to be hosted by a luminous galaxy (MK ≈ -25.5) with little star formation. In the 4 months since first detection, ASASSN-15lh radiated (1.1 ± 0.2) × 10(52) ergs, challenging the magnetar model for its engine. Copyright © 2016, American Association for the Advancement of Science.

Independence and interaction of luminance and chromatic contributions to spatial hyperacuity performance.

Science.gov (United States)

Cooper, Bonnie; Lee, Barry B

2014-04-01

Here we test interactions of luminance and chromatic input to spatial hyperacuity mechanisms. First, we tested alignment of luminance and chromatic gratings matched or mismatched in contrast polarity or grating type. Thresholds with matched gratings were low while all mismatched pairs were elevated. Second, we determined alignment acuity as a function of luminance or chromatic contrast alone or in the presence of constant contrast components of the other type. For in-phase components, performance followed the envelope of the more sensitive mechanism. However, polarity reversals revealed an asymmetric effect for luminance and chromatic conditions, which suggested that luminance can override chromatic mechanisms in hyperacuity; we interpret these findings in the context of spatial mechanisms.

MRI texture analysis in differentiating luminal A and luminal B breast cancer molecular subtypes - a feasibility study.

Science.gov (United States)

Holli-Helenius, Kirsi; Salminen, Annukka; Rinta-Kiikka, Irina; Koskivuo, Ilkka; Brück, Nina; Boström, Pia; Parkkola, Riitta

2017-12-29

The aim of this study was to use texture analysis (TA) of breast magnetic resonance (MR) images to assist in differentiating estrogen receptor (ER) positive breast cancer molecular subtypes. Twenty-seven patients with histopathologically proven invasive ductal breast cancer were selected in preliminary study. Tumors were classified into molecular subtypes: luminal A (ER-positive and/or progesterone receptor (PR)-positive, human epidermal growth factor receptor type 2 (HER2) -negative, proliferation marker Ki-67 MaZda. Texture parameters and tumour volumes were correlated with tumour prognostic factors. Textural differences were observed mainly in precontrast images. The two most discriminative texture parameters to differentiate luminal A and luminal B subtypes were sum entropy and sum variance (p = 0.003). The AUCs were 0.828 for sum entropy (p = 0.004), and 0.833 for sum variance (p = 0.003), and 0.878 for the model combining texture features sum entropy, sum variance (p = 0.001). In the LOOCV, the AUC for model combining features sum entropy and sum variance was 0.876. Sum entropy and sum variance showed positive correlation with higher Ki-67 index. Luminal B types were larger in volume and moderate correlation between larger tumour volume and higher Ki-67 index was also observed (r = 0.499, p = 0.008). Texture features which measure randomness, heterogeneity or smoothness and homogeneity may either directly or indirectly reflect underlying growth patterns of breast tumours. TA and volumetric analysis may provide a way to evaluate the biologic aggressiveness of breast tumours and provide aid in decisions regarding therapeutic efficacy.

Study on the luminous characteristics of a natural ball lightning

Science.gov (United States)

Wang, Hao; Yuan, Ping; Cen, Jianyong; Liu, Guorong

2018-02-01

According to the optical images of the whole process of a natural ball lightning recorded by two slit-less spectrographs in the Qinghai plateau of China, the simulated observation experiment on the luminous intensity of the spherical light source was carried out. The luminous intensity and the optical power of the natural ball lightning in the wavelength range of 400-690 nm were estimated based on the experimental data and the Lambert-Beer Law. The results show that the maximum luminous intensity was about 1.24 × 105 cd in the initial stage of the natural ball lightning, and the maximum luminous intensity and the maximum optical power in most time of its life were about 5.9 × 104 cd and 4.2 × 103 W, respectively.

Ecology and biology of luminous bacteria in the Arabian Sea

Digital Repository Service at National Institute of Oceanography (India)

Ramaiah, N.; Chandramohan, D.

Extensive studies on occurrence, distribution and species composition of luminous bacteria in the Arabian Sea were carried out from various habitats. Luminous bacterial population was by far the highest in the environs of the Arabian Sea...

Increasing phylogenetic resolution at low taxonomic levels using massively parallel sequencing of chloroplast genomes

Science.gov (United States)

Matthew Parks; Richard Cronn; Aaron Liston

2009-01-01

We reconstruct the infrageneric phylogeny of Pinus from 37 nearly-complete chloroplast genomes (average 109 kilobases each of an approximately 120 kilobase genome) generated using multiplexed massively parallel sequencing. We found that 30/33 ingroup nodes resolved wlth > 95-percent bootstrap support; this is a substantial improvement relative...

Life prediction of OLED for constant-stress accelerated degradation tests using luminance decaying model

Energy Technology Data Exchange (ETDEWEB)

Zhang, Jianping, E-mail: jpzhanglzu@163.com [College of Energy and Mechanical Engineering, Shanghai University of Electric Power, Shanghai 200090 (China); Li, Wenbin [College of Energy and Mechanical Engineering, Shanghai University of Electric Power, Shanghai 200090 (China); Cheng, Guoliang; Chen, Xiao [Shanghai Tianyi Electric Co., Ltd., Shanghai 201611 (China); Wu, Helen [School of Computing, Engineering and Mathematics, University of Western Sydney, Sydney 2751 (Australia); Herman Shen, M.-H. [Department of Mechanical and Aerospace Engineering, The Ohio State University, OH 43210 (United States)

2014-10-15

In order to acquire the life information of organic light emitting diode (OLED), three groups of constant stress accelerated degradation tests are performed to obtain the luminance decaying data of samples under the condition that the luminance and the current are respectively selected as the indicator of performance degradation and the test stress. Weibull function is applied to describe the relationship between luminance decaying and time, least square method (LSM) is employed to calculate the shape parameter and scale parameter, and the life prediction of OLED is achieved. The numerical results indicate that the accelerated degradation test and the luminance decaying model reveal the luminance decaying law of OLED. The luminance decaying formula fits the test data very well, and the average error of fitting value compared with the test data is small. Furthermore, the accuracy of the OLED life predicted by luminance decaying model is high, which enable rapid estimation of OLED life and provide significant guidelines to help engineers make decisions in design and manufacturing strategy from the aspect of reliability life. - Highlights: • We gain luminance decaying data by accelerated degradation tests on OLED. • The luminance decaying model objectively reveals the decaying law of OLED luminance. • The least square method (LSM) is employed to calculate Weibull parameters. • The plan designed for accelerated degradation tests proves to be feasible. • The accuracy of the OLED life and the luminance decaying fitting formula is high.

Life prediction of OLED for constant-stress accelerated degradation tests using luminance decaying model

International Nuclear Information System (INIS)

Zhang, Jianping; Li, Wenbin; Cheng, Guoliang; Chen, Xiao; Wu, Helen; Herman Shen, M.-H.

2014-01-01

In order to acquire the life information of organic light emitting diode (OLED), three groups of constant stress accelerated degradation tests are performed to obtain the luminance decaying data of samples under the condition that the luminance and the current are respectively selected as the indicator of performance degradation and the test stress. Weibull function is applied to describe the relationship between luminance decaying and time, least square method (LSM) is employed to calculate the shape parameter and scale parameter, and the life prediction of OLED is achieved. The numerical results indicate that the accelerated degradation test and the luminance decaying model reveal the luminance decaying law of OLED. The luminance decaying formula fits the test data very well, and the average error of fitting value compared with the test data is small. Furthermore, the accuracy of the OLED life predicted by luminance decaying model is high, which enable rapid estimation of OLED life and provide significant guidelines to help engineers make decisions in design and manufacturing strategy from the aspect of reliability life. - Highlights: • We gain luminance decaying data by accelerated degradation tests on OLED. • The luminance decaying model objectively reveals the decaying law of OLED luminance. • The least square method (LSM) is employed to calculate Weibull parameters. • The plan designed for accelerated degradation tests proves to be feasible. • The accuracy of the OLED life and the luminance decaying fitting formula is high

Photometric Selection of a Massive Galaxy Catalog with z ≥ 0.55

Science.gov (United States)

Núñez, Carolina; Spergel, David N.; Ho, Shirley

2017-02-01

We present the development of a photometrically selected massive galaxy catalog, targeting Luminous Red Galaxies (LRGs) and massive blue galaxies at redshifts of z≥slant 0.55. Massive galaxy candidates are selected using infrared/optical color-color cuts, with optical data from the Sloan Digital Sky Survey (SDSS) and infrared data from “unWISE” forced photometry derived from the Wide-field Infrared Survey Explorer (WISE). The selection method is based on previously developed techniques to select LRGs with z> 0.5, and is optimized using receiver operating characteristic curves. The catalog contains 16,191,145 objects, selected over the full SDSS DR10 footprint. The redshift distribution of the resulting catalog is estimated using spectroscopic redshifts from the DEEP2 Galaxy Redshift Survey and photometric redshifts from COSMOS. Restframe U - B colors from DEEP2 are used to estimate LRG selection efficiency. Using DEEP2, the resulting catalog has an average redshift of z = 0.65, with a standard deviation of σ =2.0, and an average restframe of U-B=1.0, with a standard deviation of σ =0.27. Using COSMOS, the resulting catalog has an average redshift of z = 0.60, with a standard deviation of σ =1.8. We estimate 34 % of the catalog to be blue galaxies with z≥slant 0.55. An estimated 9.6 % of selected objects are blue sources with redshift z0.55. Stellar contamination is estimated to be 1.8%.

Association of proteasomal activity with metastasis in luminal breast cancer

Science.gov (United States)

Shashova, E. E.; Fesik, E. A.; Doroshenko, A. V.

2017-09-01

Chimotrypsin-like (ChTL) and caspase-like (CL) proteasomal activities were investigated in different variants of the tumor progression of luminal breast cancer. Patients with primary luminal breast cancer (n = 123) in stage T1-3N0-2M0 who had not received neoadjuvant treatment were included in this study. Proteasome ChTL and CL activities were determined in the samples of tumor and adjacent tissues. The coefficients of chymotrypsin-like (kChTL) and caspase-like (kCL) proteasome activity were also calculated as the ratio of the corresponding activity in the tumor tissue to activity in the adjacent tissue. ChTL, CL, kChTL and kCL in the tissues of luminal A and B breast cancer with lymphogenic metastasis were compared, and their association with hematogenous metastasis was evaluated. On the one hand, CL activity of proteasomes increased in luminal A breast cancer with extensive lymphogenic metastasis (N2), on the other hand it decreased in the luminal B subtype of cancer. The ratio of proteasomal activity in the tumor and adjacent tissues plays a significant role in the hematogenic pathway of breast cancer progression and is associated with poor metastatic-free survival.

NCOA5 is correlated with progression and prognosis in luminal breast cancer

International Nuclear Information System (INIS)

Ye, Xiao-He; Huang, Du-Ping; Luo, Rong-Cheng

2017-01-01

Nuclear receptor coactivator 5 (NCOA5) is known to modulate ERα-mediated transcription and has been found to be involved in the progression of several malignancies. However, the potential correlation between NCOA5 and clinical outcome in patients with luminal breast cancer remains unknown. In the present study, we demonstrated that NCOA5 was significantly up-regulated in luminal breast cancer tissues compared with adjacent non-cancerous tissues both in validated cohort and TCGA cohort. Moreover, Kaplan-Meier analysis indicated that patients with high NOCA5 expression had significantly lower overall survival (P = 0.021). Cox regression analysis indicated that the high NOCA5 expression was independent high risk factor as well as old age (>60) and HER-2 expression (P = 0.039; P = 0.003; P = 0.005; respectively). This study provides new insights and evidences that NOCA5 over-expression was significantly correlated with progression and prognosis in luminal breast cancer. However, the precise cellular mechanisms for NOCA5 in luminal breast cancer need to be further explored. - Highlights: • NCOA5 is significantly over-expressed in human luminal breast cancer tissues. • NOCA5 was involved in the progression of luminal breast cancer. • NCOA5 can predict the progression of luminal breast cancer.

Observations of Ultra-Luminous X-ray Sources, and Implications

Science.gov (United States)

Colbert, E. J. M.

2004-05-01

I will review observations of Ultra-Luminous X-ray Sources (ULXs; Lx > 1E39 erg/s), in particular those observations that have helped reveal the nature of these curious objects. Some recent observations suggest that ULXs are a heterogenous class. Although ULX phenomenology is not fully understood, I will present some examples from the (possibly overlapping) sub-classes. Since ULXs are the most luminous objects in starburst galaxies, they, and ``normal'' luminous black-hole high-mass X-ray binaries are intimately tied to the global galaxian X-ray-star-formation connection. Further work is needed to understand how ULXs form, and how they are associated with the putative population of intermediate-mass black holes.

MASSIVE INFANT STARS ROCK THEIR CRADLE

Science.gov (United States)

2002-01-01

that are responsible for lighting up this cloud of gas. The apparently innocuous-looking star at the very center of the nebula, just below the brightest region, is actually about 30 times more massive and almost 200,000 times brighter than our Sun. The intense light and powerful stellar 'winds' from this ultra-bright star have cleared away the surrounding gas to form a large cavity. The bubble is approximately 25 light-years in diameter - about the same size as the famous star-forming Orion Nebula. The Orion Nebula is sculpted by intense radiation from newly born stars in the same way as N83B. Astronomers estimate that the spherical void in N83B must have been carved out of the nebula very recently - in astronomical terms - maybe as little as 30,000 years ago. The hottest star in N83B is 45 times more massive than the Sun and is embedded in the brightest region in the nebula. This bright region, situated just above the center, is only about 2 light-years across. The region's small size and its intense glow are telltale signs of a very young, massive star. This star is the youngest newcomer to this part of the Large Magellanic Cloud. The Hubble image shows a bright arc structure just below the luminous star. This impressive ridge may have been created in the glowing gas by the hot star's powerful wind. Measurements of the age of this star and neighboring stars in the nebula show that they are younger than the nebula's central star. Their formation may have been 'triggered' by the violent wind from the central star. This 'chain-reaction' of stellar births seems to be common in the Universe. About 20 young and luminous stars have been identified in the region, but it may well be that many more massive stars remain undetected in other areas of the Large Magellanic Cloud, hidden by dust in small clusters like N83B. To the right of the glowing N83B is a much larger diffuse nebula, known as DEM22d, which is partly obscured by an extended lane of dust and gas. This image is

AN APPARENT PRECESSING HELICAL OUTFLOW FROM A MASSIVE EVOLVED STAR: EVIDENCE FOR BINARY INTERACTION

Energy Technology Data Exchange (ETDEWEB)

Lau, R. M.; Hankins, M. J.; Herter, T. L. [Astronomy Department, Cornell University, Ithaca, NY 14853-6801 (United States); Morris, M. R. [Department of Physics and Astronomy, University of California, Los Angeles, 430 Portola Plaza, Los Angeles, CA 90095 (United States); Mills, E. A. C. [National Radio Astronomy Observatory, P.O. Box O 1009, Lopezville Drive, Socorro, NM 87801 (United States); Ressler, M. E. [Jet Propulsion Laboratory, California Institute of Technology, 4800 Oak Grove Drive, Pasadena, CA 91109 (United States)

2016-02-20

Massive, evolved stars play a crucial role in the metal enrichment, dust budget, and energetics of the interstellar medium; however, the details of their evolution are uncertain because of their rarity and short lifetimes before exploding as supernovae. Discrepancies between theoretical predictions from single-star evolutionary models and observations of massive stars have evoked a shifting paradigm that implicates the importance of binary interaction. We present mid- to far-infrared observations from the Stratospheric Observatory for Infrared Astronomy of a conical “helix” of warm dust (∼180 K) that appears to extend from the Wolf–Rayet star WR102c. Our interpretation of the helix is a precessing, collimated outflow that emerged from WR102c during a previous evolutionary phase as a rapidly rotating luminous blue variable. We attribute the precession of WR102c to gravitational interactions with an unseen compact binary companion whose orbital period can be constrained to 800 days < P < 1400 days from the inferred precession period, τ{sub p} ∼ 1.4 × 10{sup 4} yr, and limits imposed on the stellar and orbital parameters of the system. Our results concur with the range of orbital periods (P ≲ 1500 days) where spin-up via mass exchange is expected to occur for massive binary systems.

Human Mammary Luminal Epithelial Cells Contain Progenitors to Myoepithelial Cells

Energy Technology Data Exchange (ETDEWEB)

Pechoux, Christine; Gudjonsson, Thorarinn; Ronnov-Jessen, Lone; Bissell, Mina J; Petersen, Ole

1999-02-01

The origin of the epithelial and myoepithelial cells in the human breast has not been delineated. In this study we have addressed whether luminal epithelial cells and myoepithelial cells are vertically connected, i.e., whether one is the precursor for the other. We used a primary culture assay allowing preservation of basic phenotypic traits of luminal epithelial and myoepithelial cells in culture. The two cell types were then separated immunomagnetically using antibodies directed against lineage-specific cell surface antigens into at best 100% purity. The cellular identity was ascertained by cytochemistry, immunoblotting, and 2-D gel electrophoresis. Luminal epithelial cells were identified by strong expression of cytokeratins 18 and 19 while myoepithelial cells were recognized by expression of vimentin and {alpha}-smooth muscle actin. We used a previously devised culture medium (CDM4) that allows vigorous expansion of proliferative myoepithelial cells and also devised a medium (CDM6) that allowed sufficient expansion of differentiated luminal epithelial cells based on addition of hepatocyte growth factor/scatter factor. The two different culture media supported each lineage for at least five passages without signs of interconversion. We used parallel cultures where we switched culture media, thus testing the ability of each lineage to convert to the other. Whereas the myoepithelial lineage showed no signs of interconversion, a subset of luminal epithelial cells, gradually, but distinctly, converted to myoepithelial cells. We propose that in the mature human breast, it is the luminal epithelial cell compartment that gives rise to myoepithelial cells rather than the other way around.

Signal detectability of mammography depends on film-screen system and luminance of view box

International Nuclear Information System (INIS)

Maeda, Fumie; Ogura, Akio; Miyai, Akira

2003-01-01

High-density film and the high-luminance view-box system are being recommended for mammograms owing to the improved detection of masses. However, this system causes an increase in radiation. Therefore, the purpose of this study was to assess whether the detection of masses would improve using the normal-luminance view box and normal-density film with different types of contrast systems. Low-contrast detection using receiver operating characteristic (ROC) analysis and high-contrast detection using an American College of Radiology (ACR) phantom were evaluated for the following systems: high-density film and high-luminance view box, normal-density film and normal-luminance view box, and normal-density film with wide latitude and normal-luminance view box. The results showed no significant variation in the detectability of the system with high-density film and high-luminance view box and the normal-density film with wide latitude and normal-luminance view box. However, in terms of low-contrast visibility, the system using normal-density film and normal-luminance view box was significantly reduced in comparison with the others. Therefore, the system with normal-density film with wide latitude and the normal-luminance view box is recommended because of reduced radiation dose. (author)

VELOCITY-RESOLVED [C ii] EMISSION AND [C ii]/FIR MAPPING ALONG ORION WITH HERSCHEL *,**

Science.gov (United States)

Goicoechea, Javier R.; Teyssier, D.; Etxaluze, M.; Goldsmith, P.F.; Ossenkopf, V.; Gerin, M.; Bergin, E.A.; Black, J.H.; Cernicharo, J.; Cuadrado, S.; Encrenaz, P.; Falgarone, E.; Fuente, A.; Hacar, A.; Lis, D.C.; Marcelino, N.; Melnick, G.J.; Müller, H.S.P.; Persson, C.; Pety, J.; Röllig, M.; Schilke, P.; Simon, R.; Snell, R.L.; Stutzki, J.

2015-01-01

We present the first ~7.5′×11.5′ velocity-resolved (~0.2 km s−1) map of the [C ii] 158 μm line toward the Orion molecular cloud 1 (OMC 1) taken with the Herschel/HIFI instrument. In combination with far-infrared (FIR) photometric images and velocity-resolved maps of the H41α hydrogen recombination and CO J=2-1 lines, this data set provides an unprecedented view of the intricate small-scale kinematics of the ionized/PDR/molecular gas interfaces and of the radiative feedback from massive stars. The main contribution to the [C ii] luminosity (~85 %) is from the extended, FUV-illuminated face of the cloud (G0>500, nH>5×103 cm−3) and from dense PDRs (G≳104, nH≳105 cm−3) at the interface between OMC 1 and the H ii region surrounding the Trapezium cluster. Around ~15 % of the [C ii] emission arises from a different gas component without CO counterpart. The [C ii] excitation, PDR gas turbulence, line opacity (from [13C ii]) and role of the geometry of the illuminating stars with respect to the cloud are investigated. We construct maps of the L[C ii]/LFIR and LFIR/MGas ratios and show that L[C ii]/LFIR decreases from the extended cloud component (~10−2–10−3) to the more opaque star-forming cores (~10−3–10−4). The lowest values are reminiscent of the “[C ii] deficit” seen in local ultra-luminous IR galaxies hosting vigorous star formation. Spatial correlation analysis shows that the decreasing L[C ii]/LFIR ratio correlates better with the column density of dust through the molecular cloud than with LFIR/MGas. We conclude that the [C ii] emitting column relative to the total dust column along each line of sight is responsible for the observed L[C ii]/LFIR variations through the cloud. PMID:26568638

VELOCITY-RESOLVED [C ii] EMISSION AND [C ii]/FIR MAPPING ALONG ORION WITH HERSCHEL.

Science.gov (United States)

Goicoechea, Javier R; Teyssier, D; Etxaluze, M; Goldsmith, P F; Ossenkopf, V; Gerin, M; Bergin, E A; Black, J H; Cernicharo, J; Cuadrado, S; Encrenaz, P; Falgarone, E; Fuente, A; Hacar, A; Lis, D C; Marcelino, N; Melnick, G J; Müller, H S P; Persson, C; Pety, J; Röllig, M; Schilke, P; Simon, R; Snell, R L; Stutzki, J

2015-10-10

We present the first ~7.5'×11.5' velocity-resolved (~0.2 km s -1 ) map of the [C ii] 158 μ m line toward the Orion molecular cloud 1 (OMC 1) taken with the Herschel /HIFI instrument. In combination with far-infrared (FIR) photometric images and velocity-resolved maps of the H41 α hydrogen recombination and CO J =2-1 lines, this data set provides an unprecedented view of the intricate small-scale kinematics of the ionized/PDR/molecular gas interfaces and of the radiative feedback from massive stars. The main contribution to the [C ii] luminosity (~85 %) is from the extended, FUV-illuminated face of the cloud ( G 0 >500, n H >5×10 3 cm -3 ) and from dense PDRs ( G ≳10 4 , n H ≳10 5 cm -3 ) at the interface between OMC 1 and the H ii region surrounding the Trapezium cluster. Around ~15 % of the [C ii] emission arises from a different gas component without CO counterpart. The [C ii] excitation, PDR gas turbulence, line opacity (from [ 13 C ii]) and role of the geometry of the illuminating stars with respect to the cloud are investigated. We construct maps of the L [C ii]/ L FIR and L FIR / M Gas ratios and show that L [C ii]/ L FIR decreases from the extended cloud component (~10 -2 -10 -3 ) to the more opaque star-forming cores (~10 -3 -10 -4 ). The lowest values are reminiscent of the "[C ii] deficit" seen in local ultra-luminous IR galaxies hosting vigorous star formation. Spatial correlation analysis shows that the decreasing L [C ii]/ L FIR ratio correlates better with the column density of dust through the molecular cloud than with L FIR / M Gas . We conclude that the [C ii] emitting column relative to the total dust column along each line of sight is responsible for the observed L [C ii]/ L FIR variations through the cloud.

Geometry of illumination, luminance contrast, and gloss perception

OpenAIRE

Leloup, Frédéric; Pointer, Michael R.; Dutré, Philip; Hanselaer, Peter

2010-01-01

The influence of both the geometry of illumination and luminance contrast on gloss perception has been examined using the method of paired comparison. Six achromatic glass samples having different lightness were illuminated by two light sources. Only one of these light sources was visible in reflection by the observer. By separate adjustment of the intensity of both light sources, the luminance of both the reflected image and the adjacent off-specular surroundings could be individually varied...

Characteristics of estrogen-induced peroxidase in mouse uterine luminal fluid

International Nuclear Information System (INIS)

Jellinck, P.H.; Newbold, R.R.; McLachlan, J.A.

1991-01-01

Peroxidase activity in the uterine luminal fluid of mice treated with diethylstilbestrol was measured by the guaiacol assay and also by the formation of 3H2O from [2-3H]estradiol. In the radiometric assay, the generation of 3H2O and 3H-labeled water-soluble products was dependent on H2O2 (25 to 100 microM), with higher concentrations being inhibitory. Tyrosine or 2,4-dichlorophenol strongly enhanced the reaction catalyzed either by the luminal fluid peroxidase or the enzyme in the CaCl2 extract of the uterus, but decreased the formation of 3H2O from [2-3H]estradiol by lactoperoxidase in the presence of H2O2 (80 microM). NADPH, ascorbate, and cytochrome c inhibited both luminal fluid and uterine tissue peroxidase activity to the same extent, while superoxide dismutase showed a marginal activating effect. Lactoferrin, a major protein component of uterine luminal fluid, was shown not to contribute to its peroxidative activity, and such an effect by prostaglandin synthase was also ruled out. However, it was not possible to exclude eosinophil peroxidase, brought to the uterus after estrogen stimulation, as being the source of peroxidase activity in uterine luminal fluid

Study of luminous emissions associated to electron emissions in radiofrequency cavities

International Nuclear Information System (INIS)

Maissa, S.

1996-01-01

This study investigates luminous emissions simultaneously to electron emissions and examines their features in order to better understand the field electron emission phenomenon. A RF cavity, operating at room temperature and in pulsed mode, joined to a sophisticated experimental apparatus has been especially developed. The electron and luminous emissions are investigated on cleaned or with metallic, graphitic and dielectric particles contaminated RF surfaces in order to study their influence on these phenomena. During the surface processing, unstable luminous spots glowing during one RF pulse are detected. Their apparition is promoted in the vicinity of the metallic particles or scratches. Two hypotheses could explain their origin: the presence of micro-plasmas associated to electronic explosive emission during processing or the thermal radiation of the melted metal during this emission. Stable luminous spots glowing during several RF pulses are also detected and appear to increase on RF surfaces contaminated with dielectric particles, leading to strong and explosive luminous emissions. Two interpretations are considered: the initiation of surface breakdowns on the dielectric particles or the heating by the RF field at temperatures sufficiently intense to provoke their thermal radiation then their explosion. Finally a superconducting cavity has been adapted to observe luminous spots, which differ from the former ones bu their star shape and could be associated to micro-plasmas, revealed by the starbursts observed on superconducting cavity walls. (author)

Measuring high-resolution sky luminance distributions with a CCD camera.

Science.gov (United States)

Tohsing, Korntip; Schrempf, Michael; Riechelmann, Stefan; Schilke, Holger; Seckmeyer, Gunther

2013-03-10

We describe how sky luminance can be derived from a newly developed hemispherical sky imager (HSI) system. The system contains a commercial compact charge coupled device (CCD) camera equipped with a fish-eye lens. The projection of the camera system has been found to be nearly equidistant. The luminance from the high dynamic range images has been calculated and then validated with luminance data measured by a CCD array spectroradiometer. The deviation between both datasets is less than 10% for cloudless and completely overcast skies, and differs by no more than 20% for all sky conditions. The global illuminance derived from the HSI pictures deviates by less than 5% and 20% under cloudless and cloudy skies for solar zenith angles less than 80°, respectively. This system is therefore capable of measuring sky luminance with the high spatial and temporal resolution of more than a million pixels and every 20 s respectively.

Hawking radiation and the boomerang behavior of massive modes near a horizon

Science.gov (United States)

Jannes, G.; Maïssa, P.; Philbin, T. G.; Rousseaux, G.

2011-05-01

We discuss the behavior of massive modes near a horizon based on a study of the dispersion relation and wave packet simulations of the Klein-Gordon equation. We point out an apparent paradox between two (in principle equivalent) pictures of black-hole evaporation through Hawking radiation. In the picture in which the evaporation is due to the emission of positive-energy modes, one immediately obtains a threshold for the emission of massive particles. In the picture in which the evaporation is due to the absorption of negative-energy modes, such a threshold apparently does not exist. We resolve this paradox by tracing the evolution of the positive-energy massive modes with an energy below the threshold. These are seen to be emitted and move away from the black-hole horizon, but they bounce back at a “red horizon” and are reabsorbed by the black hole, thus compensating exactly for the difference between the two pictures. For astrophysical black holes, the consequences are curious but do not affect the terrestrial constraints on observing Hawking radiation. For analogue-gravity systems with massive modes, however, the consequences are crucial and rather surprising.

Luminance compensation for AMOLED displays using integrated MIS sensors

Science.gov (United States)

Vygranenko, Yuri; Fernandes, Miguel; Louro, Paula; Vieira, Manuela

2017-05-01

Active-matrix organic light-emitting diodes (AMOLEDs) are ideal for future TV applications due to their ability to faithfully reproduce real images. However, pixel luminance can be affected by instability of driver TFTs and aging effect in OLEDs. This paper reports on a pixel driver utilizing a metal-insulator-semiconductor (MIS) sensor for luminance control of the OLED element. In the proposed pixel architecture for bottom-emission AMOLEDs, the embedded MIS sensor shares the same layer stack with back-channel etched a Si:H TFTs to maintain the fabrication simplicity. The pixel design for a large-area HD display is presented. The external electronics performs image processing to modify incoming video using correction parameters for each pixel in the backplane, and also sensor data processing to update the correction parameters. The luminance adjusting algorithm is based on realistic models for pixel circuit elements to predict the relation between the programming voltage and OLED luminance. SPICE modeling of the sensing part of the backplane is performed to demonstrate its feasibility. Details on the pixel circuit functionality including the sensing and programming operations are also discussed.

Luminous flux and colour maintenance investigation of integrated LED lamps

DEFF Research Database (Denmark)

Corell, Dennis Dan; Thorseth, Anders; Dam-Hansen, Carsten

2014-01-01

This article will present an investigation of the luminous flux and colour maintenance of white LED based retrofit lamps. The study includes 23 different types of integrated LED lamps, covering 18 directional and 5 non-directional. Luminous flux and colour data for operation up to 20000 h has been...

An evaluation of organic light emitting diode monitors for medical applications: great timing, but luminance artifacts.

Science.gov (United States)

Elze, Tobias; Taylor, Christopher; Bex, Peter J

2013-09-01

In contrast to the dominant medical liquid crystal display (LCD) technology, organic light-emitting diode (OLED) monitors control the display luminance via separate light-emitting diodes for each pixel and are therefore supposed to overcome many previously documented temporal artifacts of medical LCDs. We assessed the temporal and luminance characteristics of the only currently available OLED monitor designed for use in the medical treatment field (SONY PVM2551MD) and checked the authors' main findings with another SONY OLED device (PVM2541). Temporal properties of the photometric output were measured with an optical transient recorder. Luminances of the three color primaries and white for all 256 digital driving levels (DDLs) were measured with a spectroradiometer. Between the luminances of neighboring DDLs, just noticeable differences were calculated according to a perceptual model developed for medical displays. Luminances of full screen (FS) stimuli were compared to luminances of smaller stimuli with identical DDLs. All measured luminance transition times were below 300 μs. Luminances were independent of the luminance in the preceding frame. However, for the single color primaries, up to 50.5% of the luminances of neighboring DDLs were not perceptually distinguishable. If two color primaries were active simultaneously, between 36.7% and 55.1% of neighboring luminances for increasing DDLs of the third primary were even decreasing. Moreover, luminance saturation effects were observed when too many pixels were active simultaneously. This effect was strongest for white; a small white patch was close to 400 cd/m(2), but in FS the luminance of white saturated at 162 cd/m(2). Due to different saturation levels, the luminance of FS green and FS yellow could exceed the luminance of FS white for identical DDLs. The OLED temporal characteristics are excellent and superior to those of LCDs. However, the OLEDs revealed severe perceptually relevant artifacts with

Increasing phylogenetic resolution at low taxonomic levels using massively parallel sequencing of chloroplast genomes

Directory of Open Access Journals (Sweden)

Cronn Richard

2009-12-01

Full Text Available Abstract Background Molecular evolutionary studies share the common goal of elucidating historical relationships, and the common challenge of adequately sampling taxa and characters. Particularly at low taxonomic levels, recent divergence, rapid radiations, and conservative genome evolution yield limited sequence variation, and dense taxon sampling is often desirable. Recent advances in massively parallel sequencing make it possible to rapidly obtain large amounts of sequence data, and multiplexing makes extensive sampling of megabase sequences feasible. Is it possible to efficiently apply massively parallel sequencing to increase phylogenetic resolution at low taxonomic levels? Results We reconstruct the infrageneric phylogeny of Pinus from 37 nearly-complete chloroplast genomes (average 109 kilobases each of an approximately 120 kilobase genome generated using multiplexed massively parallel sequencing. 30/33 ingroup nodes resolved with ≥ 95% bootstrap support; this is a substantial improvement relative to prior studies, and shows massively parallel sequencing-based strategies can produce sufficient high quality sequence to reach support levels originally proposed for the phylogenetic bootstrap. Resampling simulations show that at least the entire plastome is necessary to fully resolve Pinus, particularly in rapidly radiating clades. Meta-analysis of 99 published infrageneric phylogenies shows that whole plastome analysis should provide similar gains across a range of plant genera. A disproportionate amount of phylogenetic information resides in two loci (ycf1, ycf2, highlighting their unusual evolutionary properties. Conclusion Plastome sequencing is now an efficient option for increasing phylogenetic resolution at lower taxonomic levels in plant phylogenetic and population genetic analyses. With continuing improvements in sequencing capacity, the strategies herein should revolutionize efforts requiring dense taxon and character sampling

Mixing of Chromatic and Luminance Retinal Signals in Primate Area V1.

Science.gov (United States)

Li, Xiaobing; Chen, Yao; Lashgari, Reza; Bereshpolova, Yulia; Swadlow, Harvey A; Lee, Barry B; Alonso, Jose Manuel

2015-07-01

Vision emerges from activation of chromatic and achromatic retinal channels whose interaction in visual cortex is still poorly understood. To investigate this interaction, we recorded neuronal activity from retinal ganglion cells and V1 cortical cells in macaques and measured their visual responses to grating stimuli that had either luminance contrast (luminance grating), chromatic contrast (chromatic grating), or a combination of the two (compound grating). As with parvocellular or koniocellular retinal ganglion cells, some V1 cells responded mostly to the chromatic contrast of the compound grating. As with magnocellular retinal ganglion cells, other V1 cells responded mostly to the luminance contrast and generated a frequency-doubled response to equiluminant chromatic gratings. Unlike magnocellular and parvocellular retinal ganglion cells, V1 cells formed a unimodal distribution for luminance/color preference with a 2- to 4-fold bias toward luminance. V1 cells associated with positive local field potentials in deep layers showed the strongest combined responses to color and luminance and, as a population, V1 cells encoded a diverse combination of luminance/color edges that matched edge distributions of natural scenes. Taken together, these results suggest that the primary visual cortex combines magnocellular and parvocellular retinal inputs to increase cortical receptive field diversity and to optimize visual processing of our natural environment. © The Author 2014. Published by Oxford University Press. All rights reserved. For Permissions, please e-mail: journals.permissions@oup.com.

Complex organic molecules in organic-poor massive young stellar objects

DEFF Research Database (Denmark)

Fayolle, Edith C.; Öberg, Karin I.; Garrod, Robin T.

2015-01-01

to search for complex organic molecules over 8-16 GHz in the 1 mm atmospheric window toward three MYSOs with known ice abundances, but without luminous molecular hot cores. Results. Complex molecules are detected toward all three sources at comparable abundances with respect to CH3OH to classical hot core......Context. Massive young stellar objects (MYSOs) with hot cores are classic sources of complex organic molecules. The origins of these molecules in such sources, as well as the small-and large-scale differentiation between nitrogen-and oxygen-bearing complex species, are poorly understood. Aims. We...... aim to use complex molecule abundances toward a chemically less explored class of MYSOs with weak hot organic emission lines to constrain the impact of hot molecular cores and initial ice conditions on the chemical composition toward MYSOs. Methods. We use the IRAM 30 m and the Submillimeter Array...

A CANDELS-3D-HST synergy : Resolved Star Formation Patterns at 0.7

NARCIS (Netherlands)

Wuyts, S.; , van, Dokkum P.G.; , van der, Wel A.

2013-01-01

We analyze the resolved stellar populations of 473 massive star-forming galaxies at 0.7 {lt} z {lt} 1.5, with multi-wavelength broadband imaging from CANDELS and H{$α$} surface brightness profiles at the same kiloparsec resolution from 3D-HST. Together, this unique data set sheds light on how the

Massive Outflows Associated with ATLASGAL Clumps

Science.gov (United States)

Yang, A. Y.; Thompson, M. A.; Urquhart, J. S.; Tian, W. W.

2018-03-01

We have undertaken the largest survey for outflows within the Galactic plane using simultaneously observed {}13{CO} and {{{C}}}18{{O}} data. Out of a total of 919 ATLASGAL clumps, 325 have data suitable to identify outflows, and 225 (69% ± 3%) show high-velocity outflows. The clumps with detected outflows show significantly higher clump masses ({M}clump}), bolometric luminosities ({L}bol}), luminosity-to-mass ratios ({L}bol}/{M}clump}), and peak H2 column densities ({N}{{{H}}2}) compared to those without outflows. Outflow activity has been detected within the youngest quiescent clump (i.e., 70 μ {{m}} weak) in this sample, and we find that the outflow detection rate increases with {M}clump}, {L}bol}, {L}bol}/{M}clump}, and {N}{{{H}}2}, approaching 90% in some cases (UC H II regions = 93% ± 3%; masers = 86% ± 4%; HC H II regions = 100%). This high detection rate suggests that outflows are ubiquitous phenomena of massive star formation (MSF). The mean outflow mass entrainment rate implies a mean accretion rate of ∼ {10}-4 {M}ȯ {yr}}-1, in full agreement with the accretion rate predicted by theoretical models of MSF. Outflow properties are tightly correlated with {M}clump}, {L}bol}, and {L}bol}/{M}clump} and show the strongest relation with the bolometric clump luminosity. This suggests that outflows might be driven by the most massive and luminous source within the clump. The correlations are similar for both low-mass and high-mass outflows over 7 orders of magnitude, indicating that they may share a similar outflow mechanism. Outflow energy is comparable to the turbulent energy within the clump; however, we find no evidence that outflows increase the level of clump turbulence as the clumps evolve. This implies that the origin of turbulence within clumps is fixed before the onset of star formation.

SMM J04135+10277: A CANDIDATE EARLY-STAGE ''WET-DRY'' MERGER OF TWO MASSIVE GALAXIES AT z = 2.8

Energy Technology Data Exchange (ETDEWEB)

Riechers, Dominik A., E-mail: dr@astro.cornell.edu [Astronomy Department, California Institute of Technology, MC 249-17, 1200 East California Boulevard, Pasadena, CA 91125 (United States)

2013-03-10

We report interferometric imaging of CO(J = 3{yields}2) emission toward the z = 2.846 submillimeter-selected galaxy SMM J04135+10277, using the Combined Array for Research in Millimeter-wave Astronomy (CARMA). SMM J04135+10277 was previously thought to be a gas-rich, submillimeter-selected quasar, with the highest molecular gas mass among high-z quasars reported in the literature. Our maps at {approx}6 Multiplication-Sign improved linear resolution relative to earlier observations spatially resolve the emission on {approx}1.''7 scales, corresponding to a (lensing-corrected) source radius of {approx}5.2 kpc. They also reveal that the molecular gas reservoir, and thus, likely the submillimeter emission, is not associated with the host galaxy of the quasar, but with an optically faint gas-rich galaxy at 5.''2, or 41.5 kpc projected distance from the active galactic nucleus (AGN). The obscured gas-rich galaxy has a dynamical mass of M{sub dyn} sin{sup 2} i = 5.6 Multiplication-Sign 10{sup 11} M{sub Sun }, corresponding to a gas mass fraction of {approx_equal}21%. Assuming a typical M{sub BH}/M{sub *} ratio for z {approx}> 2 quasars, the two galaxies in this system have an approximate mass ratio of {approx}1.9. Our findings suggest that this quasar-starburst galaxy pair could represent an early stage of a rare major, gas-rich/gas-poor ({sup w}et-dry{sup )} merger of two massive galaxies at z = 2.8, rather than a single, gas-rich AGN host galaxy. Such systems could play an important role in the early buildup of present-day massive galaxies through a submillimeter-luminous starburst phase, and may remain hidden in larger numbers among rest-frame far-infrared-selected quasar samples at low and high redshift.

Covariation of Color and Luminance Facilitate Object Individuation in Infancy

Science.gov (United States)

Woods, Rebecca J.; Wilcox, Teresa

2010-01-01

The ability to individuate objects is one of our most fundamental cognitive capacities. Recent research has revealed that when objects vary in color or luminance alone, infants fail to individuate those objects until 11.5 months. However, color and luminance frequently covary in the natural environment, thus providing a more salient and reliable…

Massive branes

International Nuclear Information System (INIS)

Bergshoeff, E.; Ortin, T.

1998-01-01

We investigate the effective world-volume theories of branes in a background given by (the bosonic sector of) 10-dimensional massive IIA supergravity (''''massive branes'''') and their M-theoretic origin. In the case of the solitonic 5-brane of type IIA superstring theory the construction of the Wess-Zumino term in the world-volume action requires a dualization of the massive Neveu-Schwarz/Neveu-Schwarz target space 2-form field. We find that, in general, the effective world-volume theory of massive branes contains new world-volume fields that are absent in the massless case, i.e. when the mass parameter m of massive IIA supergravity is set to zero. We show how these new world-volume fields can be introduced in a systematic way. (orig.)

Optimal Solution Volume for Luminal Preservation: A Preclinical Study in Porcine Intestinal Preservation.

Science.gov (United States)

Oltean, M; Papurica, M; Jiga, L; Hoinoiu, B; Glameanu, C; Bresler, A; Patrut, G; Grigorie, R; Ionac, M; Hellström, M

2016-03-01

Rodent studies suggest that luminal solutions alleviate the mucosal injury and prolong intestinal preservation but concerns exist that excessive volumes of luminal fluid may promote tissue edema. Differences in size, structure, and metabolism between rats and humans require studies in large animals before clinical use. Intestinal procurement was performed in 7 pigs. After perfusion with histidine-tryptophan-ketoglutarate (HTK), 40-cm-long segments were cut and filled with 13.5% polyethylene glycol (PEG) 3350 solution as follows: V0 (controls, none), V1 (0.5 mL/cm), V2 (1 mL/cm), V3 (1.5 mL/cm), and V4 (2 mL/cm). Tissue and luminal solutions were sampled after 8, 14, and 24 hours of cold storage (CS). Preservation injury (Chiu score), the apical membrane (ZO-1, brush-border maltase activity), and the electrolyte content in the luminal solution were studied. In control intestines, 8-hour CS in HTK solution resulted in minimal mucosal changes (grade 1) that progressed to significant subepithelial edema (grade 3) by 24 hours. During this time, a gradual loss in ZO-1 was recorded, whereas maltase activity remained unaltered. Moreover, variable degrees of submucosal edema were observed. Luminal introduction of high volumes (2 mL/mL) of PEG solution accelerated the development of the subepithelial edema and submucosal edema, leading to worse histology. However, ZO-1 was preserved better over time than in control intestines (no luminal solution). Maltase activity was reduced in intestines receiving luminal preservation. Luminal sodium content decreased in time and did not differ between groups. This PEG solution protects the apical membrane and the tight-junction proteins but may favor water absorption and tissue (submucosal) edema, and luminal volumes >2 mL/cm may result in worse intestinal morphology. Copyright © 2016 Elsevier Inc. All rights reserved.

Asymmetric effects of luminance and chrominance in the watercolor illusion

Directory of Open Access Journals (Sweden)

Andrew eCoia

2014-09-01

Full Text Available When bounded by a line of sufficient contrast, the desaturated hue of a colored line will spread over an enclosed area, an effect known as the watercolor illusion. The contrast of the two lines can be in luminance, chromaticity, or a combination of both. The effect is most salient when the enclosing line has greater contrast with the background than the line that induces the spreading color. In most prior experiments with watercolor spreading, the luminance of both lines has been lower than the background. An achromatic version of the illusion exists where a dark line will spread while being bounded by either a darker or brighter line. In a previous study we measured the strength of the watercolor effect in which the colored inducing line was isoluminant to the background, and found an illusion for both brighter and darker achromatic outer contours. We also found the strength of spreading is stronger for bluish (+S cone input colors compared to yellowish (-S cone input ones, when bounded by a dark line. The current study set out to measure the hue dependence of the watercolor illusion when inducing colors are flanked with brighter (increment as opposed to darker outer lines. The asymmetry in the watercolor effect with S cone input was enhanced when the inducing contrast was an increment rather than a decrement. Further experiments explored the relationship between the perceived contrast of these chromatic lines when paired with luminance increments and decrements and revealed that the perceived contrast of luminance increments and decrements is dependent on which isoluminant color they are paired with. In addition to known hue asymmetries in the watercolor illusion there are asymmetries between luminance increments and decrements that are also hue dependent. These latter asymmetries may be related to the perceived contrast of the hue/luminance parings.

Asymmetric effects of luminance and chrominance in the watercolor illusion.

Science.gov (United States)

Coia, Andrew J; Crognale, Michael A

2014-01-01

When bounded by a line of sufficient contrast, the desaturated hue of a colored line will spread over an enclosed area, an effect known as the watercolor illusion. The contrast of the two lines can be in luminance, chromaticity, or a combination of both. The effect is most salient when the enclosing line has greater contrast with the background than the line that induces the spreading color. In most prior experiments with watercolor spreading, the luminance of both lines has been lower than the background. An achromatic version of the illusion exists where a dark line will spread while being bounded by either a darker or brighter line. In a previous study we measured the strength of the watercolor effect in which the colored inducing line was isoluminant to the background, and found an illusion for both brighter and darker achromatic outer contours. We also found the strength of spreading is stronger for bluish (+S cone input) colors compared to yellowish (-S cone input) ones, when bounded by a dark line. The current study set out to measure the hue dependence of the watercolor illusion when inducing colors are flanked with brighter (increment) as opposed to darker outer lines. The asymmetry in the watercolor effect with S cone input was enhanced when the inducing contrast was an increment rather than a decrement. Further experiments explored the relationship between the perceived contrast of these chromatic lines when paired with luminance increments and decrements and revealed that the perceived contrast of luminance increments and decrements is dependent on which isoluminant color they are paired with. In addition to known hue asymmetries in the watercolor illusion there are asymmetries between luminance increments and decrements that are also hue dependent. These latter asymmetries may be related to the perceived contrast of the hue/luminance parings.

A multiwavelength and multiscale study of Luminous and Ultraluminous Infrared Galaxies in the local Universe

Science.gov (United States)

Herrero-Illana, Rubén

2014-10-01

an exploratory study where, using the Paschen! emission, we developed a method to isolate the two main component of the radio emission at 8.4 GHz: thermal and non-thermal (synchrotron). This decomposition allowed us to differentiate the ages at different regions, yielding to a better understanding of starburst processes. We also studied the massive star formation in the most luminous nearby LIRG, Arp 299, through the study of supernovae (SNe), both in its most luminous nucleus (Arp 299-A) and in its surroundings. We used radio data from the e-MERLIN interferometer, obtained for the LIRGI project (PIs: J. Conway & M.A. Perez-Torres), to discover the radio counterpart of supernova SN2010P. We used additional radio data at four frequencies, for a total of 13 epochs, and modeled the light curve of SN2010P, which allowed us to type it as a IIb, i.e., a stripped-envelope core-collapse supernova. Another supernova (SN2010O) exploded in the system a few days earlier, but did not show any radio emission despite our several attempts to detect it at different epochs. This radio-silence in late time observations is probably due to its rapid evolution, compatible with a Type Ib supernova. Regarding the study of SNe in the nuclear region of Arp 299-A, we used very long baseline interferometry (VLBI) radio techniques. We analyzed several epochs spanning 2.5 years using the European VLBI Network (EVN), which permitted us to confirm 25 compact sources, most of them SNe or SN remnants, and allowed us to derive a core-collapse SN rate of !0.8 SNyr-1, compatible with previous studies. We also found that most of the star formation in Arp 299-A is taking place in the inner 150 parsecs. Our final approach to the study of (U)LIRGs consists of the use of radio-VLBI techniques aimed at resolving the innermost regions of these galaxies, where massive and violent starbursts are taking place, and where their interaction with AGN is more evident. Since radio is not affected by dust extinction and

A pocket-sized luminance meter.

NARCIS (Netherlands)

Schreuder, D.A.

1964-01-01

In many case the light technician will feel the want of assessing the luminance of certain surfaces within his field of view in a quick and convenient manner. The measurement need not be very accurate, but it should be carried out with an apparatus so small that it can easily be taken along

White LEDs with limit luminous efficacy

Energy Technology Data Exchange (ETDEWEB)

Lisitsyn, V. M.; Stepanov, S. A., E-mail: stepanovsa@tpu.ru; Yangyang, Ju [National Research Tomsk Polytechnic University, 30 Lenin Av., Tomsk, 634050 (Russian Federation); Lukash, V. S. [JSC Research Institute of Semiconductor Devices, 99a Krasnoarmeyskaja St., Tomsk, 634050 (Russian Federation)

2016-01-15

In most promising widespread gallium nitride based LEDs emission is generated in the blue spectral region with a maximum at about 450 nm which is converted to visible light with the desired spectrum by means of phosphor. The thermal energy in the conversion is determined by the difference in the energies of excitation and emission quanta and the phosphor quantum yield. Heat losses manifest themselves as decrease in the luminous efficacy. LED heating significantly reduces its efficiency and life. In addition, while heating, the emission generation output and the efficiency of the emission conversion decrease. Therefore, the reduction of the energy losses caused by heating is crucial for LED development. In this paper, heat losses in phosphor-converted LEDs (hereinafter chips) during spectrum conversion are estimated. The limit values of the luminous efficacy for white LEDs are evaluated.

Luminal epithelial cells within the mammary gland can produce basal cells upon oncogenic stress.

Science.gov (United States)

Hein, S M; Haricharan, S; Johnston, A N; Toneff, M J; Reddy, J P; Dong, J; Bu, W; Li, Y

2016-03-17

In the normal mammary gland, the basal epithelium is known to be bipotent and can generate either basal or luminal cells, whereas the luminal epithelium has not been demonstrated to contribute to the basal compartment in an intact and normally developed mammary gland. It is not clear whether cellular heterogeneity within a breast tumor results from transformation of bipotent basal cells or from transformation and subsequent basal conversion of the more differentiated luminal cells. Here we used a retroviral vector to express an oncogene specifically in a small number of the mammary luminal epithelial cells and tested their potential to produce basal cells during tumorigenesis. This in-vivo lineage-tracing work demonstrates that luminal cells are capable of producing basal cells on activation of either polyoma middle T antigen or ErbB2 signaling. These findings reveal the plasticity of the luminal compartment during tumorigenesis and provide an explanation for cellular heterogeneity within a cancer.

YOUNG STELLAR OBJECTS IN THE MASSIVE STAR-FORMING REGION W49

Energy Technology Data Exchange (ETDEWEB)

Saral, G.; Hora, J. L.; Willis, S. E. [Harvard-Smithsonian Center for Astrophysics, 60 Garden Street, Cambridge, MA 02138 (United States); Koenig, X. P. [Yale University, Department of Astronomy, 208101, New Haven, CT 06520-8101 (United States); Gutermuth, R. A. [University of Massachusetts, Department of Astronomy, Amherst, MA 01003 (United States); Saygac, A. T., E-mail: gsaral@cfa.harvard.edu [Istanbul University, Faculty of Science, Astronomy and Space Sciences Department, Istanbul-Turkey (Turkey)

2015-11-01

We present the initial results of our investigation of the star-forming complex W49, one of the youngest and most luminous massive star-forming regions in our Galaxy. We used Spitzer/Infrared Array Camera (IRAC) data to investigate massive star formation with the primary objective of locating a representative set of protostars and the clusters of young stars that are forming around them. We present our source catalog with the mosaics from the IRAC data. In this study we used a combination of IRAC, MIPS, Two Micron All Sky Survey, and UKIRT Deep Infrared Sky Survey (UKIDSS) data to identify and classify the young stellar objects (YSOs). We identified 232 Class 0/I YSOs, 907 Class II YSOs, and 74 transition disk candidate objects using color–color and color–magnitude diagrams. In addition, to understand the evolution of star formation in W49, we analyzed the distribution of YSOs in the region to identify clusters using a minimal spanning tree method. The fraction of YSOs that belong to clusters with ≥7 members is found to be 52% for a cutoff distance of 96″, and the ratio of Class II/I objects is 2.1. We compared the W49 region to the G305 and G333 star-forming regions and concluded that W49 has the richest population, with seven subclusters of YSOs.

The Black Hole Safari: Big Game Hunting in 30+ Massive Galaxies

Science.gov (United States)

McConnell, Nicholas J.; Ma, Chung-Pei; Janish, Ryan; Gebhardt, Karl; Lauer, Tod R.; Graham, James R.

2015-01-01

The current census of the most massive black holes in the local universe turns up an odd variety of galaxy hosts: central galaxies in rich clusters, second- or lower-ranked cluster members, and compact relics from the early universe. More extensive campaigns are required to explore the number density and environmental distribution of these monsters. Over the past three years we have collected a large set of stellar kinematic data with sufficient resolution to detect the gravitational signatures of supermassive black holes with MBH > 109 MSun. This Black Hole Safari targets enormous galaxies at the centers of nearby galaxy clusters, as well as their similarly luminous counterparts in weaker galaxy groups. To date we have observed more than 30 early-type galaxies with integral-field spectrographs on the Keck, Gemini North, and Gemini South telescopes. Here I present preliminary stellar kinematics from 10 objects.

Nonlinear mapping of the luminance in dual-layer high dynamic range displays

Science.gov (United States)

Guarnieri, Gabriele; Ramponi, Giovanni; Bonfiglio, Silvio; Albani, Luigi

2009-02-01

It has long been known that the human visual system (HVS) has a nonlinear response to luminance. This nonlinearity can be quantified using the concept of just noticeable difference (JND), which represents the minimum amplitude of a specified test pattern an average observer can discern from a uniform background. The JND depends on the background luminance following a threshold versus intensity (TVI) function. It is possible to define a curve which maps physical luminances into a perceptually linearized domain. This mapping can be used to optimize a digital encoding, by minimizing the visibility of quantization noise. It is also commonly used in medical applications to display images adapting to the characteristics of the display device. High dynamic range (HDR) displays, which are beginning to appear on the market, can display luminance levels outside the range in which most standard mapping curves are defined. In particular, dual-layer LCD displays are able to extend the gamut of luminance offered by conventional liquid crystals towards the black region; in such areas suitable and HVS-compliant luminance transformations need to be determined. In this paper we propose a method, which is primarily targeted to the extension of the DICOM curve used in medical imaging, but also has a more general application. The method can be modified in order to compensate for the ambient light, which can be significantly greater than the black level of an HDR display and consequently reduce the visibility of the details in dark areas.

The most luminous heavily obscured quasars have a high merger fraction: morphological study of wise -selected hot dust-obscured galaxies

Energy Technology Data Exchange (ETDEWEB)

Fan, Lulu; Gao, Ying; Zhang, Dandan; Jiang, Xiaoming; Wu, Qiaoqian; Yang, Jun; Li, Zhao [Shandong Provincial Key Lab of Optical Astronomy and Solar-Terrestrial Environment, Institute of Space Science, Shandong University, Weihai 264209 (China); Han, Yunkun [Yunnan Observatories, Chinese Academy of Sciences, Kunming 650011 (China); Fang, Guanwen, E-mail: llfan@sdu.edu.cn, E-mail: hanyk@ynao.ac.cn [Institute for Astronomy and History of Science and Technology, Dali University, Dali 671003 (China)

2016-05-10

Previous studies have shown that Wide-field Infrared Survey Explorer -selected hyperluminous, hot dust-obscured galaxies (Hot DOGs) are powered by highly dust-obscured, possibly Compton-thick active galactic nuclei (AGNs). High obscuration provides us a good chance to study the host morphology of the most luminous AGNs directly. We analyze the host morphology of 18 Hot DOGs at z ∼ 3 using Hubble Space Telescope /WFC3 imaging. We find that Hot DOGs have a high merger fraction (62 ± 14%). By fitting the surface brightness profiles, we find that the distribution of Sérsic indices in our Hot DOG sample peaks around 2, which suggests that most Hot DOGs have transforming morphologies. We also derive the AGN bolometric luminosity (∼10{sup 14} L {sub ⊙}) of our Hot DOG sample by using IR spectral energy distributions decomposition. The derived merger fraction and AGN bolometric luminosity relation is well consistent with the variability-based model prediction. Both the high merger fraction in an IR-luminous AGN sample and relatively low merger fraction in a UV/optical-selected, unobscured AGN sample can be expected in the merger-driven evolutionary model. Finally, we conclude that Hot DOGs are merger-driven and may represent a transit phase during the evolution of massive galaxies, transforming from the dusty starburst-dominated phase to the unobscured QSO phase.

Massive Gravity

OpenAIRE

de Rham, Claudia

2014-01-01

We review recent progress in massive gravity. We start by showing how different theories of massive gravity emerge from a higher-dimensional theory of general relativity, leading to the Dvali–Gabadadze–Porrati model (DGP), cascading gravity, and ghost-free massive gravity. We then explore their theoretical and phenomenological consistency, proving the absence of Boulware–Deser ghosts and reviewing the Vainshtein mechanism and the cosmological solutions in these models. Finally, we present alt...

Resolving the Polarized Dust Emission of the Disk around the Massive Star Powering the HH 80–81 Radio Jet

Science.gov (United States)

Girart, J. M.; Fernández-López, M.; Li, Z.-Y.; Yang, H.; Estalella, R.; Anglada, G.; Áñez-López, N.; Busquet, G.; Carrasco-González, C.; Curiel, S.; Galvan-Madrid, R.; Gómez, J. F.; de Gregorio-Monsalvo, I.; Jiménez-Serra, I.; Krasnopolsky, R.; Martí, J.; Osorio, M.; Padovani, M.; Rao, R.; Rodríguez, L. F.; Torrelles, J. M.

2018-04-01

Here we present deep (16 μJy beam‑1), very high (40 mas) angular resolution 1.14 mm, polarimetric, Atacama Large Millimeter/submillimeter Array (ALMA) observations toward the massive protostar driving the HH 80–81 radio jet. The observations clearly resolve the disk oriented perpendicularly to the radio jet, with a radius of ≃0.″171 (∼291 au at 1.7 kpc distance). The continuum brightness temperature, the intensity profile, and the polarization properties clearly indicate that the disk is optically thick for a radius of R ≲ 170 au. The linear polarization of the dust emission is detected almost all along the disk, and its properties suggest that dust polarization is produced mainly by self-scattering. However, the polarization pattern presents a clear differentiation between the inner (optically thick) part of the disk and the outer (optically thin) region of the disk, with a sharp transition that occurs at a radius of ∼0.″1 (∼170 au). The polarization characteristics of the inner disk suggest that dust settling has not occurred yet with a maximum dust grain size between 50 and 500 μm. The outer part of the disk has a clear azimuthal pattern but with a significantly higher polarization fraction compared to the inner disk. This pattern is broadly consistent with the self-scattering of a radiation field that is beamed radially outward, as expected in the optically thin outer region, although contribution from non-spherical grains aligned with respect to the radiative flux cannot be excluded.

Effect of Ionizing Radiation on Luminous Bacteria Cells

International Nuclear Information System (INIS)

Kudryasheva, N.; Rozhko, T.; Alexandrova, M.; Vasyunkina, E.; Arkhipova, V.

2011-01-01

Marine luminous bacteria were used to monitor toxicity of alpha- (Am-241, U-235+238) and beta- (tritium) radionuclide solutions. Increase or inhibition of bacterial luminescence was observed under exposure to radionuclides. Radiation toxicity of Am and chemical toxicity of U were demonstrated. Effects of U were similar to those of stable heavy metals: sensitivity was about 10-5 M. Sensitivity of the bacteria to Am-241 was 300 Bq/L (10 -11 M). Inhibition of bacterial growth was observed under exposure to Am-241 and tritium. Role of peroxides and electron transfer processes in the effects of radionuclides on luminous bacteria is discussed.

Psychophysical and physiological responses to gratings with luminance and chromatic components of different spatial frequencies.

Science.gov (United States)

Cooper, Bonnie; Sun, Hao; Lee, Barry B

2012-02-01

Gratings that contain luminance and chromatic components of different spatial frequencies were used to study the segregation of signals in luminance and chromatic pathways. Psychophysical detection and discrimination thresholds to these compound gratings, with luminance and chromatic components of the one either half or double the spatial frequency of the other, were measured in human observers. Spatial frequency tuning curves for detection of compound gratings followed the envelope of those for luminance and chromatic gratings. Different grating types were discriminable at detection threshold. Fourier analysis of physiological responses of macaque retinal ganglion cells to compound waveforms showed chromatic information to be restricted to the parvocellular pathway and luminance information to the magnocellular pathway. Taken together, the human psychophysical and macaque physiological data support the strict segregation of luminance and chromatic information in independent channels, with the magnocellular and parvocellular pathways, respectively, serving as likely the physiological substrates. © 2012 Optical Society of America

A Blind Pilot: Who is a Super-Luminal Observer?

Directory of Open Access Journals (Sweden)

Rabounski D.

2008-04-01

Full Text Available This paper discusses the nature of a hypothetical super-luminal observer who, as well as a real (sub-light speed observer, perceives the world by light waves. This consideration is due to that fact that the theory of relativity permits different frames of reference, including light-like and super-luminal reference frames. In analogy with a blind pilot on board a supersonic jet aeroplane (or missile, perceived by blind people, it is concluded that the light barrier is observed in the framework of only the light signal exchange experiment.

Relationship of the luminous bacterial symbiont of the Caribbean flashlight fish, Kryptophanaron alfredi (family Anomalopidae) to other luminous bacteria based on bacterial luciferase (luxA) genes.

Science.gov (United States)

Haygood, M G

1990-01-01

Flashlight fishes (family Anomalopidae) have light organs that contain luminous bacterial symbionts. Although the symbionts have not yet been successfully cultured, the luciferase genes have been cloned directly from the light organ of the Caribbean species, Kryptophanaron alfredi. The goal of this project was to evaluate the relationship of the symbiont to free-living luminous bacteria by comparison of genes coding for bacterial luciferase (lux genes). Hybridization of a lux AB probe from the Kryptophanaron alfredi symbiont to DNAs from 9 strains (8 species) of luminous bacteria showed that none of the strains tested had lux genes highly similar to the symbiont. The most similar were a group consisting of Vibrio harveyi, Vibrio splendidus and Vibrio orientalis. The nucleotide sequence of the luciferase alpha subunit gene luxA) of the Kryptophanaron alfredi symbiont was determined in order to do a more detailed comparison with published luxA sequences from Vibrio harveyi, Vibrio fischeri and Photobacterium leiognathi. The hybridization results, sequence comparisons and the mol% G + C of the Kryptophanaron alfredi symbiont luxA gene suggest that the symbiont may be considered as a new species of luminous Vibrio related to Vibrio harveyi.

Rotationally resolved flurorescence as a probe of molecular photoionization dynamics

International Nuclear Information System (INIS)

Poliakoff, E.D.; Kakar, S.; Choi, H.C.

1993-01-01

We present rotationally resolved data for N 2 (2σ u -1 ) photoionization in the excitation energy range 19 ≤ hν ≤ 35 eV. These are the first rotationally resolved measurements on the photoion over an extended spectral range above the ionization threshold. The requisite resolution is obtained by measuring rotationally resolved fluorescence from electronically excited photoions created by synchrotron radiation. This technique is useful for studying dynamical features embedded deep in the ionization continua and should supplement laser-based methods that are limited to probing near-threshold phenomena. The present study shows that the outgoing photoelectron can alter the rotational motion of the more massive photoion by exchanging angular momentum and this partitioning of angular momentum depends on the ionization dynamics. Thus, our data directly probe electron-molecule interactions and are sensitive probes of scattering dynamics. We are currently investigating dynamical features such as shape resonances and Cooper minima with rotational resolution for deciphering microscopic aspects of molecular scattering and these efforts will be discussed

Densities, cellulases, alginate and pectin lyases of luminous and other heterotrophic bacteria associated with marine algae

Digital Repository Service at National Institute of Oceanography (India)

Ramaiah, N.; Chandramohan, D.

Epiphytic luminous and non-luminous bacteria were determined quantitatively for eight intertidal algal species from rocky beaches of Goa and Lakshadweep coral reef lagoon. Luminous bacteria were present on all eight algal species and contributed 2...

Massive clot formation after tooth extraction

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Santosh Hunasgi

2015-01-01

Full Text Available Oral surgical procedures mainly tooth extraction can be related with an extended hemorrhage owed to the nature of the process resulting in an "open wound." The attempt of this paper is to present a case of massive postoperative clot formation after tooth extraction and highlight on the oral complications of surgical procedures. A 32-year-old male patient reported to the Dental Clinic for evaluation and extraction of grossly decayed 46. Clinical evaluation of 46 revealed root stumps. Extraction of the root stumps was performed, and it was uneventful. Hemostasis was achieved and postsurgical instructions were specified to the patient. The patient reported to the clinic, the very subsequent morning with a criticism of bleeding at the extraction site. On clinical examination, bleeding was noted from the socket in relation to 46. To control bleeding, oral hemostatic drugs Revici - E (Ethamsylate 500 mg was prescribed and bleeding was stopped in 2 h. However, a massive clot was formed at the extraction site. Further, this clot resolved on its own in 1-week time. Despite the fact that dental extraction is considered to be a minor surgical procedure, some cases may present with life-threatening complications including hemorrhage. Vigilant and significant history taking, physical and dental examinations prior to dental procedures are a must to avoid intraoperative and postoperative complications.

Reproducibility of airway luminal size in asthma measured by HRCT.

Science.gov (United States)

Brown, Robert H; Henderson, Robert J; Sugar, Elizabeth A; Holbrook, Janet T; Wise, Robert A

2017-10-01

Brown RH, Henderson RJ, Sugar EA, Holbrook JT, Wise RA, on behalf of the American Lung Association Airways Clinical Research Centers. Reproducibility of airway luminal size in asthma measured by HRCT. J Appl Physiol 123: 876-883, 2017. First published July 13, 2017; doi:10.1152/japplphysiol.00307.2017.-High-resolution CT (HRCT) is a well-established imaging technology used to measure lung and airway morphology in vivo. However, there is a surprising lack of studies examining HRCT reproducibility. The CPAP Trial was a multicenter, randomized, three-parallel-arm, sham-controlled 12-wk clinical trial to assess the use of a nocturnal continuous positive airway pressure (CPAP) device on airway reactivity to methacholine. The lack of a treatment effect of CPAP on clinical or HRCT measures provided an opportunity for the current analysis. We assessed the reproducibility of HRCT imaging over 12 wk. Intraclass correlation coefficients (ICCs) were calculated for individual airway segments, individual lung lobes, both lungs, and air trapping. The ICC [95% confidence interval (CI)] for airway luminal size at total lung capacity ranged from 0.95 (0.91, 0.97) to 0.47 (0.27, 0.69). The ICC (95% CI) for airway luminal size at functional residual capacity ranged from 0.91 (0.85, 0.95) to 0.32 (0.11, 0.65). The ICC measurements for airway distensibility index and wall thickness were lower, ranging from poor (0.08) to moderate (0.63) agreement. The ICC for air trapping at functional residual capacity was 0.89 (0.81, 0.94) and varied only modestly by lobe from 0.76 (0.61, 0.87) to 0.95 (0.92, 0.97). In stable well-controlled asthmatic subjects, it is possible to reproducibly image unstimulated airway luminal areas over time, by region, and by size at total lung capacity throughout the lungs. Therefore, any changes in luminal size on repeat CT imaging are more likely due to changes in disease state and less likely due to normal variability. NEW & NOTEWORTHY There is a surprising lack

Luminal Cells Are Favored as the Cell of Origin for Prostate Cancer

Directory of Open Access Journals (Sweden)

Zhu A. Wang

2014-09-01

Full Text Available The identification of cell types of origin for cancer has important implications for tumor stratification and personalized treatment. For prostate cancer, the cell of origin has been intensively studied, but it has remained unclear whether basal or luminal epithelial cells, or both, represent cells of origin under physiological conditions in vivo. Here, we use a novel lineage-tracing strategy to assess the cell of origin in a diverse range of mouse models, including Nkx3.1+/−; Pten+/−, Pten+/−, Hi-Myc, and TRAMP mice, as well as a hormonal carcinogenesis model. Our results show that luminal cells are consistently the observed cell of origin for each model in situ; however, explanted basal cells from these mice can generate tumors in grafts. Consequently, we propose that luminal cells are favored as cells of origin in many contexts, whereas basal cells only give rise to tumors after differentiation into luminal cells.

The time course of color- and luminance-based salience effects.

Directory of Open Access Journals (Sweden)

Isabel C Dombrowe

2010-11-01

Full Text Available Salient objects in the visual field attract our attention. Recent work in the orientation domain has shown that the effects of the relative salience of two singleton elements on covert visual attention disappear over time. The present study aims to investigate how salience derived from color and luminance differences affects covert selection. In two experiments, observers indicated the location of a probe which was presented at different stimulus-onset-asynchronies after the presentation of a singleton display containing a homogeneous array of oriented lines and two distinct color singletons (Experiment 1 or luminance singletons (Experiment 2. The results show that relative singleton salience from luminance and color differences, just as from orientation differences, affects covert visual attention in a brief time span after stimulus onset. The mere presence of an object, however, can affect covert attention for a longer time span regardless of salience.

The impact of luminance on tonic and phasic pupillary responses to sustained cognitive load.

Science.gov (United States)

Peysakhovich, Vsevolod; Vachon, François; Dehais, Frédéric

2017-02-01

Pupillary reactions independent of light conditions have been linked to cognition for a long time. However, the light conditions can impact the cognitive pupillary reaction. Previous studies underlined the impact of luminance on pupillary reaction, but it is still unclear how luminance modulates the sustained and transient components of pupillary reaction - tonic pupil diameter and phasic pupil response. In the present study, we investigated the impact of the luminance on these two components under sustained cognitive load. Fourteen participants performed a novel working memory task combining mathematical computations with a classic n-back task. We studied both tonic pupil diameter and phasic pupil response under low (1-back) and high (2-back) working memory load and two luminance levels (gray and white). We found that the impact of working memory load on the tonic pupil diameter was modulated by the level of luminance, the increase in tonic pupil diameter with the load being larger under lower luminance. In contrast, the smaller phasic pupil response found under high load remained unaffected by luminance. These results showed that luminance impacts the cognitive pupillary reaction - tonic pupil diameter (phasic pupil response) being modulated under sustained (respectively, transient) cognitive load. These findings also support the relationship between the locus-coeruleus system, presumably functioning in two firing modes - tonic and phasic - and the pupil diameter. We suggest that the tonic pupil diameter tracks the tonic activity of the locus-coeruleus while phasic pupil response reflects its phasic activity. Besides, the designed novel cognitive paradigm allows the simultaneous manipulation of sustained and transient components of the cognitive load and is useful for dissociating the effects on the tonic pupil diameter and phasic pupil response. Copyright © 2016 Elsevier B.V. All rights reserved.

SPECTRAL AND SPATIAL SELECTIVITY OF LUMINANCE VISION IN REEF FISH

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Ulrike E Siebeck

2014-09-01

Full Text Available Luminance vision has high spatial resolution and is used for form vision and texture discrimination. In humans, birds and bees luminance channel is spectrally selective – it depends on the signals of the long-wavelength sensitive photoreceptors (bees or on the sum of long- and middle- wavelength sensitive cones (humans, but not on the signal of the short-wavelength sensitive (blue photoreceptors. The reasons of such selectivity are not fully understood. The aim of this study is to reveal the inputs of cone signals to high resolution luminance vision in reef fish. 16 freshly caught damselfish, Pomacentrus amboinensis, were trained to discriminate stimuli differing either in their colour or in their fine patterns (stripes vs. cheques. Three colours (‘bright green’, ‘dark green’ and ‘blue’ were used to create two sets of colour and two sets of pattern stimuli. The ‘bright green’ and ‘dark green’ were similar in their chromatic properties for fish, but differed in their lightness; the ‘dark green’ differed from ‘blue’ in the signal for the blue cone, but yielded similar signals in the long-wavelength and middle-wavelength cones. Fish easily learned to discriminate ‘bright green’ from ‘dark green’ and ‘dark green’ from ‘blue’ stimuli. Fish also could discriminate the fine patterns created from ‘dark green’ and ‘bright green’. However, fish failed to discriminate fine patterns created from ‘blue’ and ‘dark green’ colours, i.e. the colours that provided contrast for the blue-sensitive photoreceptor, but not for the long-wavelength sensitive one. High resolution luminance vision in damselfish, Pomacentrus amboinensis, does not have input from the blue-sensitive cone, which may indicate that the spectral selectivity of luminance channel is a general feature of visual processing in both aquatic and terrestrial animals.

Effects of background and contour luminance on the hue and brightness of the Watercolor effect.

Science.gov (United States)

Gerardin, Peggy; Dojat, Michel; Knoblauch, Kenneth; Devinck, Frédéric

2018-03-01

Conjoint measurement was used to investigate the joint influences of the luminance of the background and the inner contour on hue- and brightness filling-in for a stimulus configuration generating a water-color effect (WCE), i.e., a wiggly bi-chromatic contour enclosing a region with the lower luminance component on the exterior. Two stimuli with the background and inner contour luminances covarying independently were successively presented, and in separate experiments, the observer judged which member of the pair's interior regions contained a stronger hue or was brighter. Braided-contour control stimuli that generated little or no perceptual filling-in were also used to assess whether observers were judging the interior regions and not the contours themselves. Three nested models of the contributions of the background and inner contour to the judgments were fit to the data by maximum likelihood and evaluated by likelihood ratio tests. Both stimulus components contributed to both the hue and brightness of the interior region with increasing luminance of the inner contour generating an assimilative filling-in for the hue judgments but a contrast effect for the brightness judgments. Control analyses showed negligible effects for the order of the luminance of the background or inner contour on the judgments. An additive contribution of both components was rejected in favor of a saturated model in which the responses depended on the levels of both stimulus components. For the hue judgments, increased background luminance led to greater hue filling-in at higher luminances of the interior contour. For the brightness judgments, the higher background luminance generated less brightness filling-in at higher luminances of the interior contour. The results indicate different effects of the inner contour and background on the induction of the brightness and coloration percepts of the WCE, suggesting that they are mediated by different mechanisms. Copyright © 2018 Elsevier

Competition between color and luminance for target selection in smooth pursuit and saccadic eye movements.

Science.gov (United States)

Spering, Miriam; Montagnini, Anna; Gegenfurtner, Karl R

2008-11-24

Visual processing of color and luminance for smooth pursuit and saccadic eye movements was investigated using a target selection paradigm. In two experiments, stimuli were varied along the dimensions color and luminance, and selection of the more salient target was compared in pursuit and saccades. Initial pursuit was biased in the direction of the luminance component whereas saccades showed a relative preference for color. An early pursuit response toward luminance was often reversed to color by a later saccade. Observers' perceptual judgments of stimulus salience, obtained in two control experiments, were clearly biased toward luminance. This choice bias in perceptual data implies that the initial short-latency pursuit response agrees with perceptual judgments. In contrast, saccades, which have a longer latency than pursuit, do not seem to follow the perceptual judgment of salience but instead show a stronger relative preference for color. These substantial differences in target selection imply that target selection processes for pursuit and saccadic eye movements use distinctly different weights for color and luminance stimuli.

Massive runaway stars in the Large Magellanic Cloud

Science.gov (United States)

Gvaramadze, V. V.; Kroupa, P.; Pflamm-Altenburg, J.

2010-09-01

The origin of massive field stars in the Large Magellanic Cloud (LMC) has long been an enigma. The recent measurements of large offsets (˜ 100 km s-1) between the heliocentric radial velocities of some very massive (O2-type) field stars and the systemic LMC velocity provides a possible explanation of this enigma and suggests that the field stars are runaway stars ejected from their birthplaces at the very beginning of their parent cluster's dynamical evolution. A straightforward way to prove this explanation is to measure the proper motions of the field stars and to show that they are moving away from one of the nearby star clusters or OB associations. This approach is, however, complicated by the long distance to the LMC, which makes accurate proper motion measurements difficult. We used an alternative approach for solving the problem (first applied for Galactic field stars), based on the search for bow shocks produced by runaway stars. The geometry of detected bow shocks would allow us to infer the direction of stellar motion, thereby determining their possible parent clusters. In this paper we present the results of a search for bow shocks around six massive field stars that have been proposed as candidate runaway stars. Using archival Spitzer Space Telescope data, we found a bow shock associated with one of our programme stars, the O2 V((f*)) star BI 237, which is the first-ever detection of bow shocks in the LMC. Orientation of the bow shock suggests that BI 237 was ejected from the OB association LH 82 (located at ≃ 120 pc in projection from the star). A by-product of our search is the detection of bow shocks generated by four OB stars in the field of the LMC and an arc-like structure attached to the candidate luminous blue variable R81 (HD 269128). The geometry of two of these bow shocks is consistent with the possibility that their associated stars were ejected from the 30 Doradus star-forming complex. We discuss implications of our findings for the

Exploring the luminosity evolution and stellar mass assembly of 2SLAQ luminous red galaxies between redshifts 0.4 and 0.8

Science.gov (United States)

Banerji, Manda; Ferreras, Ignacio; Abdalla, Filipe B.; Hewett, Paul; Lahav, Ofer

2010-03-01

We present an analysis of the evolution of 8625 luminous red galaxies (LRGs) between z = 0.4 and 0.8 in the 2dF and Sloan Digital Sky Survey LRG and QSO (2SLAQ) survey. The LRGs are split into redshift bins and the evolution of both the luminosity and stellar mass function with redshift is considered and compared to the assumptions of a passive evolution scenario. We draw attention to several sources of systematic error that could bias the evolutionary predictions made in this paper. While the inferred evolution is found to be relatively unaffected by the exact choice of spectral evolution model used to compute K + e corrections, we conclude that photometric errors could be a source of significant bias in colour-selected samples such as this, in particular when using parametric maximum likelihood based estimators. We find that the evolution of the most massive LRGs is consistent with the assumptions of passive evolution and that the stellar mass assembly of the LRGs is largely complete by z ~ 0.8. Our findings suggest that massive galaxies with stellar masses above 1011Msolar must have undergone merging and star formation processes at a very early stage (z >~ 1). This supports the emerging picture of downsizing in both the star formation as well as the mass assembly of early-type galaxies. Given that our spectroscopic sample covers an unprecedentedly large volume and probes the most massive end of the galaxy mass function, we find that these observational results present a significant challenge for many current models of galaxy formation.

Near-field visual acuity of pigeons: effects of head location and stimulus luminance.

Science.gov (United States)

Hodos, W; Leibowitz, R W; Bonbright, J C

1976-03-01

Two pigeons were trained to discriminate a grating stimulus from a blank stimulus of equivalent luminance in a three-key chamber. The stimuli and blanks were presented behind a transparent center key. The procedure was a conditional discrimination in which pecks on the left key were reinforced if the blank had been present behind the center key and pecks on the right key were reinforced if the grating had been present behind the center key. The spatial frequency of the stimuli was varied in each session from four to 29.5 lines per millimeter in accordance with a variation of the method of constant stimuli. The number of lines per millimeter that the subjects could discriminate at threshold was determined from psychometric functions. Data were collected at five values of stimulus luminance ranging from--0.07 to 3.29 log cd/m2. The distance from the stimulus to the anterior nodal point of the eye, which was determined from measurements taken from high-speed motion-picture photographs of three additional pigeons and published intraocular measurements, was 62.0 mm. This distance and the grating detection thresholds were used to calculate the visual acuity of the birds at each level of luminance. Acuity improved with increasing luminance to a peak value of 0.52, which corresponds to a visual angle of 1.92 min, at a luminance of 2.33 log cd/m2. Further increase in luminance produced a small decline in acuity.

Mercury-free electrodeless discharge lamp: effect of xenon pressure and plasma parameters on luminance

International Nuclear Information System (INIS)

Nazri Dagang Ahmad; Kondo, Akira; Motomura, Hideki; Jinno, Masafumi

2009-01-01

Since there is much concern about environmental preservation, the authors have paid attention to the uses of mercury in lighting application. They have focused on the application of the xenon low-pressure inductively coupled plasma (ICP) discharge in developing cylindrical type mercury-free light sources. ICP can be operated at low filling gas pressures and demonstrates significant potential in producing high density plasma. Xenon pressure was varied from 0.1 to 100 Torr and the lamp luminance was measured. The gas pressure dependence shows an increase in luminance at pressures below 1 Torr. In order to clarify this behaviour, measurement of plasma parameters was carried out using the double probe method and its relation to lamp luminance is discussed. As the gas pressure is decreased (from 1 to 0.01 Torr), the electron temperature increases while the electron density decreases while at the same time the lamp luminance increases. There are several factors that are believed to contribute to the increase in luminance in the very low pressure region. Increases in luminance are considered to be due to the electron-ion recombination process which brings a strong recombination radiation in continuum in the visible region and also due to the effect of stochastic heating.

Luminance gradient at object borders communicates object location to the human oculomotor system.

Science.gov (United States)

Kilpeläinen, Markku; Georgeson, Mark A

2018-01-25

The locations of objects in our environment constitute arguably the most important piece of information our visual system must convey to facilitate successful visually guided behaviour. However, the relevant objects are usually not point-like and do not have one unique location attribute. Relatively little is known about how the visual system represents the location of such large objects as visual processing is, both on neural and perceptual level, highly edge dominated. In this study, human observers made saccades to the centres of luminance defined squares (width 4 deg), which appeared at random locations (8 deg eccentricity). The phase structure of the square was manipulated such that the points of maximum luminance gradient at the square's edges shifted from trial to trial. The average saccade endpoints of all subjects followed those shifts in remarkable quantitative agreement. Further experiments showed that the shifts were caused by the edge manipulations, not by changes in luminance structure near the centre of the square or outside the square. We conclude that the human visual system programs saccades to large luminance defined square objects based on edge locations derived from the points of maximum luminance gradients at the square's edges.

A luminous X-ray outburst from an intermediate-mass black hole in an off-centre star cluster

Science.gov (United States)

Lin, Dacheng; Strader, Jay; Carrasco, Eleazar R.; Page, Dany; Romanowsky, Aaron J.; Homan, Jeroen; Irwin, Jimmy A.; Remillard, Ronald A.; Godet, Olivier; Webb, Natalie A.; Baumgardt, Holger; Wijnands, Rudy; Barret, Didier; Duc, Pierre-Alain; Brodie, Jean P.; Gwyn, Stephen D. J.

2018-06-01

A unique signature for the presence of massive black holes in very dense stellar regions is occasional giant-amplitude outbursts of multi-wavelength radiation from tidal disruption and subsequent accretion of stars that make a close approach to the black holes1. Previous strong tidal disruption event (TDE) candidates were all associated with the centres of largely isolated galaxies2-6. Here, we report the discovery of a luminous X-ray outburst from a massive star cluster at a projected distance of 12.5 kpc from the centre of a large lenticular galaxy. The luminosity peaked at 1043 erg s-1 and decayed systematically over 10 years, approximately following a trend that supports the identification of the event as a TDE. The X-ray spectra were all very soft, with emission confined to be ≲3.0 keV, and could be described with a standard thermal disk. The disk cooled significantly as the luminosity decreased—a key thermal-state signature often observed in accreting stellar-mass black holes. This thermal-state signature, coupled with very high luminosities, ultrasoft X-ray spectra and the characteristic power-law evolution of the light curve, provides strong evidence that the source contains an intermediate-mass black hole with a mass tens of thousand times that of the solar mass. This event demonstrates that one of the most effective means of detecting intermediate-mass black holes is through X-ray flares from TDEs in star clusters.

Paul Callaghan luminous moments

CERN Document Server

Callaghan, Paul

2013-01-01

Acknowledged internationally for his ground-breaking scientific research in the field of magnetic resonance, Sir Paul Callaghan was a scientist and visionary with a rare gift for promoting science to a wide audience. He was named New Zealander of the Year in 2011. His death in early 2012 robbed New Zealand of an inspirational leader. Paul Callaghan: Luminous Moments brings together some of his most significant writing. Whether he describes his childhood in Wanganui, reflects on discovering the beauty of science, sets out New Zealand's future potential or discusses the experience of fa

The ER stress sensor PERK luminal domain functions as a molecular chaperone to interact with misfolded proteins

Energy Technology Data Exchange (ETDEWEB)

Wang, Peng; Li, Jingzhi; Sha, Bingdong

2016-11-29

PERK is one of the major sensor proteins which can detect the protein-folding imbalance generated by endoplasmic reticulum (ER) stress. It remains unclear how the sensor protein PERK is activated by ER stress. It has been demonstrated that the PERK luminal domain can recognize and selectively interact with misfolded proteins but not native proteins. Moreover, the PERK luminal domain may function as a molecular chaperone to directly bind to and suppress the aggregation of a number of misfolded model proteins. The data strongly support the hypothesis that the PERK luminal domain can interact directly with misfolded proteins to induce ER stress signaling. To illustrate the mechanism by which the PERK luminal domain interacts with misfolded proteins, the crystal structure of the human PERK luminal domain was determined to 3.2 Å resolution. Two dimers of the PERK luminal domain constitute a tetramer in the asymmetric unit. Superimposition of the PERK luminal domain molecules indicated that the β-sandwich domain could adopt multiple conformations. It is hypothesized that the PERK luminal domain may utilize its flexible β-sandwich domain to recognize and interact with a broad range of misfolded proteins.

LUMINOUS BURIED ACTIVE GALACTIC NUCLEI AS A FUNCTION OF GALAXY INFRARED LUMINOSITY REVEALED THROUGH SPITZER LOW-RESOLUTION INFRARED SPECTROSCOPY

International Nuclear Information System (INIS)

Imanishi, Masatoshi

2009-01-01

We present the results of Spitzer Infrared Spectrograph 5-35 μm low-resolution spectroscopic energy diagnostics of ultraluminous infrared galaxies (ULIRGs) at z> 0.15, classified optically as non-Seyferts. Based on the equivalent widths of polycyclic aromatic hydrocarbon emission and the optical depths of silicate dust absorption features, we searched for signatures of intrinsically luminous, but optically elusive, buried active galactic nuclei (AGNs) in these optically non-Seyfert ULIRGs. We then combined the results with those of non-Seyfert ULIRGs at z IR 12 L sun . We found that the energetic importance of buried AGNs clearly increases with galaxy infrared luminosity, becoming suddenly discernible in ULIRGs with L IR > 10 12 L sun . For ULIRGs with buried AGN signatures, a significant fraction of infrared luminosities can be accounted for by the detected buried AGN and modestly obscured (A V < 20 mag) starburst activity. The implied masses of spheroidal stellar components in galaxies for which buried AGNs become important roughly correspond to the value separating red massive and blue less-massive galaxies in the local universe. Our results may support the widely proposed AGN-feedback scenario as the origin of galaxy downsizing phenomena, where galaxies with currently larger stellar masses previously had higher AGN energetic contributions and star formation originating infrared luminosities, and have finished their major star formation more quickly, due to stronger AGN feedback.

Relationships between luminance and visual acuity in the rhesus monkey

Science.gov (United States)

Cavonius, C. R.; Robbins, D. O.

1973-01-01

1. The ability of rhesus monkeys to detect the gap in Landolt ring test-objects that were presented against background luminances between 5 × 10-5 cd/m2 and 5 × 103 cd/m2 was compared with similar human data. 2. At high luminance-levels the acuity of human observers is slightly better than that of rhesus, but rhesus have better acuity at scotopic luminance-levels. Both species have distinct photopic and scotopic acuity functions that cross at 6 × 10-3 cd/m2. 3. The threshold for light detection is estimated to be the same for both species when specified in quanta incident on the retina. 4. It is concluded that the receptor and neural mechanisms that mediate visual-acuity function similarly in rhesus and man, and that the differences in acuity that were measured in the two species may be attributed to optical rather than to physiological factors. PMID:4199366

Luminal progenitors restrict their lineage potential during mammary gland development.

Science.gov (United States)

Rodilla, Veronica; Dasti, Alessandro; Huyghe, Mathilde; Lafkas, Daniel; Laurent, Cécile; Reyal, Fabien; Fre, Silvia

2015-02-01

The hierarchical relationships between stem cells and progenitors that guide mammary gland morphogenesis are still poorly defined. While multipotent basal stem cells have been found within the myoepithelial compartment, the in vivo lineage potential of luminal progenitors is unclear. Here we used the expression of the Notch1 receptor, previously implicated in mammary gland development and tumorigenesis, to elucidate the hierarchical organization of mammary stem/progenitor cells by lineage tracing. We found that Notch1 expression identifies multipotent stem cells in the embryonic mammary bud, which progressively restrict their lineage potential during mammary ductal morphogenesis to exclusively generate an ERαneg luminal lineage postnatally. Importantly, our results show that Notch1-labelled cells represent the alveolar progenitors that expand during pregnancy and survive multiple successive involutions. This study reveals that postnatal luminal epithelial cells derive from distinct self-sustained lineages that may represent the cells of origin of different breast cancer subtypes.

Geometry of illumination, luminance contrast, and gloss perception.

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Leloup, Frédéric B; Pointer, Michael R; Dutré, Philip; Hanselaer, Peter

2010-09-01

The influence of both the geometry of illumination and luminance contrast on gloss perception has been examined using the method of paired comparison. Six achromatic glass samples having different lightness were illuminated by two light sources. Only one of these light sources was visible in reflection by the observer. By separate adjustment of the intensity of both light sources, the luminance of both the reflected image and the adjacent off-specular surroundings could be individually varied. It was found that visual gloss appraisal did not correlate with instrumentally measured specular gloss; however, psychometric contrast seemed to be a much better correlate. It has become clear that not only the sample surface characteristics determine gloss perception: the illumination geometry could be an even more important factor.

Luminance-based specular gloss characterization

OpenAIRE

Leloup, Frédéric; Pointer, Michael R.; Dutré, Philip; Hanselaer, Peter

2011-01-01

Gloss is a feature of visual appearance that arises from the directionally selective reflection of light incident on a surface. Especially when a distinct reflected image is perceptible, the luminance distribution of the illumination scene above the sample can strongly influence the gloss perception. For this reason, industrial glossmeters do not provide a satisfactory gloss estimation of high-gloss surfaces. In this study, the influence of the conditions of illumination on specular ...

Discovery of a new bona fide luminous blue variable in Norma

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Gvaramadze, V. V.; Kniazev, A. Y.; Berdnikov, L. N.

2015-12-01

We report the results of optical spectroscopy of the candidate evolved massive star MN44 revealed via detection of a circular shell with the Spitzer Space Telescope. First spectra taken in 2009 May-June showed the Balmer lines in emission as well as numerous emission lines of iron, which is typical of luminous blue variables (LBVs) near the visual maximum. New observations carried out in 2015 May-September detected significant changes in the spectrum, indicating that the star became hotter. We found that these changes are accompanied by significant brightness variability of MN44. In particular, the Ic-band brightness decreased by ≈ 1.6 mag during the last six years and after reaching its minimum in 2015 June has started to increase. Using archival data, we also found that the Ic-band brightness increased by ≈3 mag in ≈30 yr preceding our observations. MN44 therefore represents the 17th known example of the Galactic bona fide LBVs. We detected a nitrogen-rich knot to the north-west of the star, which might represent an interstellar cloudlet interacting with the circumstellar shell. We discuss a possible association between MN44 and the INTEGRAL transient source of hard X-ray emission IGR J16327-4940, implying that MN44 might be either a colliding-wind binary or a high-mass X-ray binary.

The Role of Luminance and Chromaticity on Symmetry Detection

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Chia-Ching Wu

2011-05-01

Full Text Available We investigated the effect of luminance and chromaticity on symmetry detection with the noise masking paradigm. In each trial, a random dot noise mask was presented in both intervals. A symmetric target was randomly presented in one interval while a random dot control was presented in the other. The orientation of the symmetric axis of the target was either 45°or −45° diagonal. The task of the observer was to determine which interval contained a symmetric target. The dots in both the target and the mask was painted with 1 to 4 colors selected from white, black, red, green, blue and yellow. We measured the target density threshold at various noise densities. Our results showed that when the number of the colors in the images was equal, the thresholds were lower in the luminance conditions than in the chromaticity conditions. In addition, the thresholds decreased with the increment of the number of the colors in the images. This suggests that (1 the luminance symmetry detection mechanism is more sensitive than chromaticity one and (2 that, contrasted to the prediction of an uncertainty model, the diversity in color facilitates symmetry detection.

Cloning and characterization of luciferase from a Fijian luminous click beetle.

Science.gov (United States)

Mitani, Yasuo; Futahashi, Ryo; Niwa, Kazuki; Ohba, Nobuyoshi; Ohmiya, Yoshihiro

2013-01-01

Luminous click beetle is distributed almost exclusively in Central and South America with a single genus in Melanesia. Among these click beetles, the description of Melanesian species has been fragmentary, and its luciferase gene and phylogenetic relation to other click beetles still remain uncertain. We collected a living luminous click beetle, Photophorus jansonii in Fiji. It emits green-yellow light from two spots on the pronotum and has no ventral luminous organ. Here, we cloned a luciferase gene from this insect by RT-PCR. The deduced amino acid sequence showed high identity of ~85% to the luciferases derived from other click beetle species. The luciferase of the Fijian click beetle was produced as a recombinant protein to characterize its biochemical properties. The Km for D-luciferin and ATP were 173 and 270 μm, respectively. The luciferase was pH-insensitive and the spectrum measured at pH 8.0 showed a peak at 559 nm, which was in the range of green-yellow light as seen in the luminous spot of the living Fijian click beetle. The Fijian click beetle luciferase was assigned to the Elateridae clade by a phylogenetic analysis, but it made a clearly different branch from Pyrophorus group examined in this study. © 2013 The American Society of Photobiology.

Massive Black Hole Implicated in Stellar Destruction

Science.gov (United States)

2010-01-01

New results from NASA's Chandra X-ray Observatory and the Magellan telescopes suggest that a dense stellar remnant has been ripped apart by a black hole a thousand times as massive as the Sun. If confirmed, this discovery would be a cosmic double play: it would be strong evidence for an intermediate mass black hole, which has been a hotly debated topic, and would mark the first time such a black hole has been caught tearing a star apart. This scenario is based on Chandra observations, which revealed an unusually luminous source of X-rays in a dense cluster of old stars, and optical observations that showed a peculiar mix of elements associated with the X-ray emission. Taken together, a case can be made that the X-ray emission is produced by debris from a disrupted white dwarf star that is heated as it falls towards a massive black hole. The optical emission comes from debris further out that is illuminated by these X-rays. The intensity of the X-ray emission places the source in the "ultraluminous X-ray source" or ULX category, meaning that it is more luminous than any known stellar X-ray source, but less luminous than the bright X-ray sources (active galactic nuclei) associated with supermassive black holes in the nuclei of galaxies. The nature of ULXs is a mystery, but one suggestion is that some ULXs are black holes with masses between about a hundred and several thousand times that of the Sun, a range intermediate between stellar-mass black holes and supermassive black holes located in the nuclei of galaxies. This ULX is in a globular cluster, a very old and crowded conglomeration of stars. Astronomers have suspected that globular clusters could contain intermediate-mass black holes, but conclusive evidence for this has been elusive. "Astronomers have made cases for stars being torn apart by supermassive black holes in the centers of galaxies before, but this is the first good evidence for such an event in a globular cluster," said Jimmy Irwin of the University

Accurate method for luminous transmittance and signal detection quotients measurements in sunglasses lenses

Science.gov (United States)

Loureiro, A. D.; Gomes, L. M.; Ventura, L.

2018-02-01

The international standard ISO 12312-1 proposes transmittance tests that quantify how dark sunglasses lenses are and whether or not they are suitable for driving. To perform these tests a spectrometer is required. In this study, we present and analyze theoretically an accurate alternative method for performing these measurements using simple components. Using three LEDs and a four-channel sensor we generated weighting functions similar to the standard ones for luminous and traffic lights transmittances. From 89 sunglasses lens spectroscopy data, we calculated luminous transmittance and signal detection quotients using our obtained weighting functions and the standard ones. Mean-difference Tukey plots were used to compare the results. All tested sunglasses lenses were classified in the right category and correctly as suitable or not for driving. The greatest absolute errors for luminous transmittance and red, yellow, green and blue signal detection quotients were 0.15%, 0.17, 0.06, 0.04 and 0.18, respectively. This method will be used in a device capable to perform transmittance tests (visible, traffic lights and ultraviolet (UV)) according to the standard. It is important to measure rightly luminous transmittance and relative visual attenuation quotients to report correctly whether or not sunglasses are suitable for driving. Moreover, standard UV requirements depend on luminous transmittance.

Luminance and chromatic contributions to a hyperacuity task: isolation by contrast polarity and target separation.

Science.gov (United States)

Sun, Hao; Cooper, Bonnie; Lee, Barry B

2012-03-01

Vernier thresholds are known to be elevated when a target pair has opposite contrast polarity. Polarity reversal is used to assess the role of luminance and chromatic pathways in hyperacuity performance. Psychophysical hyperacuity thresholds were measured for pairs of gratings of various combinations of luminance (Lum) and chromatic (Chr) contrast polarities, at different ratios of luminance to chromatic contrast. With two red-green gratings of matched luminance and chromatic polarity (+Lum+Chr), there was an elevation of threshold at isoluminance. When both luminance and chromatic polarity were mismatched (-Lum-Chr), thresholds were substantially elevated under all conditions. With the same luminance contrast polarity and opposite chromatic polarity (+Lum-Chr) thresholds were only elevated close to isoluminance; in the reverse condition (-Lum+Chr), thresholds were elevated as in the -Lum-Chr condition except close to equiluminance. Similar data were obtained for gratings isolating the short-wavelength cone mechanism. Further psychophysical measurements assessed the role of target separation with matched or mismatched contrast polarity; similar results were found for luminance and chromatic gratings. Comparison physiological data were collected from parafoveal ganglion cells of the macaque retina. Positional precision of ganglion cell signals was assessed under conditions related to the psychophysical measurements. On the basis of these combined observations, it is argued that both magnocellular, parvocellular, and koniocellular pathways have access to cortical positional mechanisms associated with vernier acuity. Copyright © 2012 Elsevier Ltd. All rights reserved.

High-protein diet modifies colonic microbiota and luminal environment but not colonocyte metabolism in the rat model: the increased luminal bulk connection.

Science.gov (United States)

Liu, Xinxin; Blouin, Jean-Marc; Santacruz, Arlette; Lan, Annaïg; Andriamihaja, Mireille; Wilkanowicz, Sabina; Benetti, Pierre-Henri; Tomé, Daniel; Sanz, Yolanda; Blachier, François; Davila, Anne-Marie

2014-08-15

High-protein diets are used for body weight reduction, but consequences on the large intestine ecosystem are poorly known. Here, rats were fed for 15 days with either a normoproteic diet (NP, 14% protein) or a hyperproteic-hypoglucidic isocaloric diet (HP, 53% protein). Cecum and colon were recovered for analysis. Short- and branched-chain fatty acids, as well as lactate, succinate, formate, and ethanol contents, were markedly increased in the colonic luminal contents of HP rats (P diet, whereas the amount of butyrate in feces was increased (P diet consumption allows maintenance in the luminal butyrate concentration and thus its metabolism in colonocytes despite modified microbiota composition and increased substrate availability. Copyright © 2014 the American Physiological Society.

Lessons Learned from resolving massive IPS database change for SPADES+

International Nuclear Information System (INIS)

Kim, Jin-Soo

2016-01-01

Safety Parameter Display and Evaluation System+ (SPADES+) was implemented to meet the requirements for Safety Parameter Display System (SPDS) which are related to TMI Action Plan requirements. SPADES+ monitors continuously the critical safety function during normal, abnormal, and emergency operation mode and generates the alarm output to the alarm server when the tolerance related to safety functions are not satisfied. The alarm algorithm for critical safety function is performed in the NSSS Application Software (NAPS) server of the Information Process System (IPS) and the calculation result will be displayed on the flat panel display (FPD) of the IPS. SPADES+ provides the critical variable to the control room operators to aid them in rapidly and reliable determining the safety status of the plant. Many database point ID names (518 points) were changed. POINT_ID is used in the programming source code, the related documents such as SDS and SRS, and Graphic database. To reduce human errors, computer program and office program’s Macro are used. Though the automatic methods are used for changing POINT_IDs, it takes lots of time to resolve for editing the change list except for making computerized solutions. In IPS, there are many more programs than SPADES+ and over 30,000 POINT_IDs are in IPS database. Changing POINT_IDs could be a burden to software engineers. In case of Ovation system database, there is the Alias field to prevent this kind of problem. The Alias is a kind of secondary key in database

ON THE AVERAGE DENSITY PROFILE OF DARK-MATTER HALOS IN THE INNER REGIONS OF MASSIVE EARLY-TYPE GALAXIES

International Nuclear Information System (INIS)

Grillo, C.

2012-01-01

We study a sample of 39 massive early-type lens galaxies at redshift z ∼< 0.3 to determine the slope of the average dark-matter density profile in the innermost regions. We keep the strong-lensing and stellar population synthesis modeling as simple as possible to measure the galaxy total and luminous masses. By rescaling the values of the Einstein radius and dark-matter projected mass with the values of the luminous effective radius and mass, we combine all the data of the galaxies in the sample. We find that between 0.3 and 0.9 times the value of the effective radius the average logarithmic slope of the dark-matter projected density profile is –1.0 ± 0.2 (i.e., approximately isothermal) or –0.7 ± 0.5 (i.e., shallower than isothermal), if, respectively, a constant Chabrier or heavier, Salpeter-like stellar initial mass function is adopted. These results provide positive evidence of the influence of the baryonic component on the contraction of the galaxy dark-matter halos, compared to the predictions of dark-matter-only cosmological simulations, and open a new way to test models of structure formation and evolution within the standard ΛCDM cosmological scenario.

Spatiotemporal Characteristics for the Depth from Luminance Contrast

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Kazuya Matsubara

2011-05-01

Full Text Available Images with higher luminance contrast tend to be perceived closer in depth. To investigate a spatiotemporal characteristic of this effect, we evaluated subjective depth of a test stimulus with various spatial and temporal frequencies. For the purpose, the depth of a reference stimulus was matched to that of the test stimulus by changing the binocular disparity. The results showed that the test stimulus was perceived closer with higher luminance contrast for all conditions. Contrast efficiency was obtained from the contrast that provided the subjective depth for each spatiotemporal frequency. The shape of the contrast efficiency function was spatially low-pass and temporally band-pass. This characteristic is different from the one measure for a detection task. This suggests that only subset of contrast signals are used for depth from contrast.

SPECIFIC CHARACTERISTICS OF BRAIN METASTASIZING IN PATIENTS WITH LUMINAL SUBTYPE OF BREAST CANCER

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A. S. Balkanov

2016-01-01

Full Text Available Background: More than half of female patients with breast cancer are diagnosed with a  luminal subtype of the disease; however, specific characteristics of its metastases to the brain have been not well studied, unlike those of HER2 positive and triple negative subtypes. Aim: A  comparative analysis of characteristics of metastatic brain lesions in patients with luminal breast cancer. Materials and methods: The time from surgery for breast cancer to the first recurrence and to metastatic brain lesions (assessed by contrast-enhanced MRI imaging was measured in 41 patients with luminal subtype of breast cancer (median age, 49.5±9.6  years, depending on a  diameter of the primary tumor and numbers of involved axillary lymph nodes. Results: The time interval to occurrence of brain metastases in luminal subtype of breast cancer is not associated with the size of the tumor. If≥4  axillary lymph nodes are involved (N2–3, brain metastases are identified much earlier (p<0.05 than in patients with N0–1 (34.5±23.9 months and 62.7±50 months, respectively. Neither the size nor the involvement of axillary lymph nodes has any impact on the rates of metastatic lesion to the brain during the first recurrence. Conclusion: Brain metastases occur at a much shorter time in those patients of luminal subtype of breast cancer who have metastases in≥4  axillary lymph nodes. Brain metastases develop in 50% of patients with the first recurrence of the luminal subtype of breast cancer.

["Glare vision". I. Physiological principles of vision change with increased test field luminance].

Science.gov (United States)

Hauser, B; Ochsner, H; Zrenner, E

1992-02-01

Clinical tests of visual acuity are an important measure of visual function. However visual acuity is usually determined only in narrow range of luminance levels between 160 and 320 cd/m2; therefore losses of visual acuity in other ranges of light intensity can not be detected. In a distance of 80 cm from the patients eyes, Landolt rings of varying sizes were presented on a small test field whose light intensity can be varied between 0.1 and 30,000 cd/m2. Thereby an acuity-luminance-function can be obtained. We studied such functions under different conditions of exposure time both with constant and with increasing luminance of the test field. We found that persons with normal vision can increase their visual acuity with increasing test field luminance up to a range of 5000 cd/m2. The maximum values of visual acuity under optimal lightening conditions lie (varying with age) between 2.2 and 0.9. Under pathological conditions visual acuity falls at high luminances accompanied by sensations of glare. Tests of glare sensitivity as a function of exposure time showed 4 sec to be a critical time of exposure since after 4 sec normal persons just reach their maximum visual acuity at high luminances. The underlying physiological mechanisms lead us to suppose that patients with neuronal light adaptation disturbances display a greater visual loss as a result of decreased time of exposure than those with disturbances in the ocular media. Visual acuity as well as the capacity to increase the patients visual acuity under optimal conditions of lighting were both found to be strongly age-dependent.(ABSTRACT TRUNCATED AT 250 WORDS)

Epimorphin mediates mammary luminal morphogenesis through control of C/EBPbeta

International Nuclear Information System (INIS)

Hirai, Yohei; Radisky, Derek; Boudreau, Rosanne; Simian, Marina; Stevens, Mary E.; Oka, Yumiko; Takebe, Kyoko; Niwa, Shinichiro; Bissell, Mina J.

2002-01-01

We have previously shown that epimorphin, a protein expressed on the surface of myoepithelial and fibroblast cells of the mammary gland, acts as a multifunctional morphogen of mammary epithelial cells. Here, we present the molecular mechanism by which epimorphin mediates luminal morphogenesis. Treatment of cells with epimorphin to induce lumen formation greatly increases the overall expression of transcription factor CCAAT/enhancer binding protein beta (C/EBPbeta) and alters the relative expression of its two principal isoforms, LIP and LAP. These alterations were shown to be essential for the morphogenetic activities, as constitutive expression of LIP was sufficient to produce lumen formation, while constitutive expression of LAP blocked epimorphin-mediated luminal morphogenesis. Furthermore, in a transgenic mouse model in which epimorphin expression was expressed in an apolar fashion on the surface of mammary epithelial cells, we found increased expression of C/EBPbeta, increased relative expression of LIP to LAP, and enlarged ductal lumina. Together, our studies demonstrate a role for epimorphin in luminal morphogenesis through control of C/EBPbeta expression

Dynamic encoding of natural luminance sequences by LGN bursts.

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Nicholas A Lesica

2006-07-01

Full Text Available In the lateral geniculate nucleus (LGN of the thalamus, visual stimulation produces two distinct types of responses known as tonic and burst. Due to the dynamics of the T-type Ca(2+ channels involved in burst generation, the type of response evoked by a particular stimulus depends on the resting membrane potential, which is controlled by a network of modulatory connections from other brain areas. In this study, we use simulated responses to natural scene movies to describe how modulatory and stimulus-driven changes in LGN membrane potential interact to determine the luminance sequences that trigger burst responses. We find that at low resting potentials, when the T channels are de-inactivated and bursts are relatively frequent, an excitatory stimulus transient alone is sufficient to evoke a burst. However, to evoke a burst at high resting potentials, when the T channels are inactivated and bursts are relatively rare, prolonged inhibitory stimulation followed by an excitatory transient is required. We also observe evidence of these effects in vivo, where analysis of experimental recordings demonstrates that the luminance sequences that trigger bursts can vary dramatically with the overall burst percentage of the response. To characterize the functional consequences of the effects of resting potential on burst generation, we simulate LGN responses to different luminance sequences at a range of resting potentials with and without a mechanism for generating bursts. Using analysis based on signal detection theory, we show that bursts enhance detection of specific luminance sequences, ranging from the onset of excitatory sequences at low resting potentials to the offset of inhibitory sequences at high resting potentials. These results suggest a dynamic role for burst responses during visual processing that may change according to behavioral state.

Optical system for a universal luminance meter

NARCIS (Netherlands)

Schreuder, D.A.

1965-01-01

There is a need for luminance meters in various fields of photometry having these characteristics: a- objective method of measurements. b. variable shape and size of measurement area. c- absence of parallax during aiming operations. d- Possibility of observing the part of the field of view to be

The effects of luminance contribution from large fields to chromatic visual evoked potentials.

Science.gov (United States)

Skiba, Rafal M; Duncan, Chad S; Crognale, Michael A

2014-02-01

Though useful from a clinical and practical standpoint uniform, large-field chromatic stimuli are likely to contain luminance contributions from retinal inhomogeneities. Such contribution can significantly influence psychophysical thresholds. However, the degree to which small luminance artifacts influence the chromatic VEP has been debated. In particular, claims have been made that band-pass tuning observed in chromatic VEPs result from luminance intrusion. However, there has been no direct evidence presented to support these claims. Recently, large-field isoluminant stimuli have been developed to control for intrusion from retinal inhomogeneities with particular regard to the influence of macular pigment. We report here the application of an improved version of these full-field stimuli to directly test the influence of luminance intrusion on the temporal tuning of the chromatic VEP. Our results show that band-pass tuning persists even when isoluminance is achieved throughout the extent of the stimulus. In addition, small amounts of luminance intrusion affect neither the shape of the temporal tuning function nor the major components of the VEP. These results support the conclusion that the chromatic VEP can depart substantially from threshold psychophysics with regard to temporal tuning and that obtaining a low-pass function is not requisite evidence of selective chromatic activation in the VEP. Copyright © 2013 Elsevier Ltd. All rights reserved.

Maturation of polarization and luminance contrast sensitivities in cuttlefish (Sepia officinalis).

Science.gov (United States)

Cartron, Lelia; Dickel, Ludovic; Shashar, Nadav; Darmaillacq, Anne-Sophie

2013-06-01

Polarization sensitivity is a characteristic of the visual system of cephalopods. It has been well documented in adult cuttlefish, which use polarization sensitivity in a large range of tasks such as communication, orientation and predation. Because cuttlefish do not benefit from parental care, their visual system (including the ability to detect motion) must be efficient from hatching to enable them to detect prey or predators. We studied the maturation and functionality of polarization sensitivity in newly hatched cuttlefish. In a first experiment, we examined the response of juvenile cuttlefish from hatching to the age of 1 month towards a moving, vertically oriented grating (contrasting and polarized stripes) using an optomotor response apparatus. Cuttlefish showed differences in maturation of polarization versus luminance contrast motion detection. In a second experiment, we examined the involvement of polarization information in prey preference and detection in cuttlefish of the same age. Cuttlefish preferentially chose not to attack transparent prey whose polarization contrast had been removed with a depolarizing filter. Performances of prey detection based on luminance contrast improved with age. Polarization contrast can help cuttlefish detect transparent prey. Our results suggest that polarization is not a simple modulation of luminance information, but rather that it is processed as a distinct channel of visual information. Both luminance and polarization sensitivity are functional, though not fully matured, in newly hatched cuttlefish and seem to help in prey detection.

LLAMA: normal star formation efficiencies of molecular gas in the centres of luminous Seyfert galaxies

Science.gov (United States)

Rosario, D. J.; Burtscher, L.; Davies, R. I.; Koss, M.; Ricci, C.; Lutz, D.; Riffel, R.; Alexander, D. M.; Genzel, R.; Hicks, E. H.; Lin, M.-Y.; Maciejewski, W.; Müller-Sánchez, F.; Orban de Xivry, G.; Riffel, R. A.; Schartmann, M.; Schawinski, K.; Schnorr-Müller, A.; Saintonge, A.; Shimizu, T.; Sternberg, A.; Storchi-Bergmann, T.; Sturm, E.; Tacconi, L.; Treister, E.; Veilleux, S.

2018-02-01

Using new Atacama Pathfinder Experiment and James Clerk Maxwell Telescope spectroscopy of the CO 2→1 line, we undertake a controlled study of cold molecular gas in moderately luminous (Lbol = 1043-44.5 erg s-1) active galactic nuclei (AGN) and inactive galaxies from the Luminous Local AGN with Matched Analogs (LLAMA) survey. We use spatially resolved infrared photometry of the LLAMA galaxies from 2MASS, the Wide-field Infrared Survey Explorer the Infrared Astronomical Satellite and the Herschel Space Observatory (Herschel), corrected for nuclear emission using multicomponent spectral energy distribution fits, to examine the dust-reprocessed star formation rates, molecular gas fractions and star formation efficiencies (SFEs) over their central 1-3 kpc. We find that the gas fractions and central SFEs of both active and inactive galaxies are similar when controlling for host stellar mass and morphology (Hubble type). The equivalent central molecular gas depletion times are consistent with the discs of normal spiral galaxies in the local Universe. Despite energetic arguments that the AGN in LLAMA should be capable of disrupting the observable cold molecular gas in their central environments, our results indicate that nuclear radiation only couples weakly with this phase. We find a mild preference for obscured AGN to contain higher amounts of central molecular gas, which suggests connection between AGN obscuration and the gaseous environment of the nucleus. Systems with depressed SFEs are not found among the LLAMA AGN. We speculate that the processes that sustain the collapse of molecular gas into dense pre-stellar cores may also be a prerequisite for the inflow of material on to AGN accretion discs.

EXPLORING THE z = 3-4 MASSIVE GALAXY POPULATION WITH ZFOURGE: THE PREVALENCE OF DUSTY AND QUIESCENT GALAXIES

Energy Technology Data Exchange (ETDEWEB)

Spitler, Lee R.; Rees, Glen [Department of Physics and Astronomy, Macquarie University, Sydney, NSW 2109 (Australia); Straatman, Caroline M. S.; Labbé, Ivo [Leiden Observatory, Leiden University, P.O. Box 9513, 2300 RA Leiden (Netherlands); Glazebrook, Karl; Kacprzak, Glenn G.; Nanayakkara, Themiya [Centre for Astrophysics and Supercomputing, Swinburne University, Hawthorn, VIC 3122 (Australia); Tran, Kim-Vy H.; Papovich, Casey; Kawinwanichakij, Lalitwadee; Mehrtens, Nicola; Tilvi, Vithal; Tomczak, Adam R. [George P. and Cynthia W. Mitchell Institute for Fundamental Physics and Astronomy, Department of Physics and Astronomy, Texas A and M University, College Station, TX 77843 (United States); Quadri, Ryan F.; Persson, S. Eric; Kelson, Daniel D.; McCarthy, Patrick J.; Monson, Andrew J. [Carnegie Observatories, Pasadena, CA 91101 (United States); Van Dokkum, Pieter [Department of Astronomy, Yale University, New Haven, CT 06520 (United States); Allen, Rebecca, E-mail: lee.spitler@mq.edu.au [Australian Astronomical Observatory, P.O. Box 296 Epping, NSW 1710 (Australia)

2014-06-01

Our understanding of the redshift z > 3 galaxy population relies largely on samples selected using the popular ''dropout'' technique, typically consisting of UV-bright galaxies with blue colors and prominent Lyman breaks. As it is currently unknown if these galaxies are representative of the massive galaxy population, we here use the FOURSTAR Galaxy Evolution (ZFOURGE) survey to create a stellar mass-limited sample at z = 3-4. Uniquely, ZFOURGE uses deep near-infrared medium-bandwidth filters to derive accurate photometric redshifts and stellar population properties. The mass-complete sample consists of 57 galaxies with log M >10.6, reaching below M {sup *} at z = 3-4. On average, the massive z = 3-4 galaxies are extremely faint in the observed optical with median R{sub tot}{sup AB}=27.48±0.41 (rest-frame M {sub 1700} = –18.05 ± 0.37). They lie far below the UV luminosity-stellar mass relation for Lyman break galaxies and are about ∼100 × fainter at the same mass. The massive galaxies are red (R – K {sub s} {sub AB} = 3.9 ± 0.2; rest-frame UV-slope β = –0.2 ± 0.3) likely from dust or old stellar ages. We classify the galaxy spectral energy distributions by their rest-frame U–V and V–J colors and find a diverse population: 46{sub −6−17}{sup +6+10}% of the massive galaxies are quiescent, 40{sub −6−5}{sup +6+7}% are dusty star-forming galaxies, and only 14{sub −3−4}{sup +3+10}% resemble luminous blue star-forming Lyman break galaxies. This study clearly demonstrates an inherent diversity among massive galaxies at higher redshift than previously known. Furthermore, we uncover a reservoir of dusty star-forming galaxies with 4 × lower specific star-formation rates compared to submillimeter-selected starbursts at z > 3. With 5 × higher numbers, the dusty galaxies may represent a more typical mode of star formation compared to submillimeter-bright starbursts.

Wavelength and ambient luminance dependence of laser eye dazzle.

Science.gov (United States)

Williamson, Craig A; McLin, Leon N; Rickman, J Michael; Manka, Michael A; Garcia, Paul V; Kinerk, Wesley T; Smith, Peter A

2017-10-10

A series of experiments has been conducted to quantify the effects of laser wavelength and ambient luminance on the severity of laser eye dazzle experienced by human subjects. Eight laser wavelengths in the visible spectrum were used (458-647 nm) across a wide range of ambient luminance conditions (0.1-10,000  cd·m -2 ). Subjects were exposed to laser irradiance levels up to 600  μW·cm -2 and were asked to recognize the orientation of optotypes at varying eccentricities up to 31.6 deg of visual angle from the laser axis. More than 40,000 data points were collected from 14 subjects (ages 23-64), and these were consolidated into a series of obscuration angles for comparison to a theoretical model of laser eye dazzle. Scaling functions were derived to allow the model to predict the effects of laser dazzle on vision more accurately by including the effects of ambient luminance and laser wavelength. The updated model provides an improved match to observed laser eye dazzle effects across the full range of conditions assessed. The resulting model will find use in a variety of laser safety applications, including the estimation of maximum dazzle exposure and nominal ocular dazzle distance values.

Massive Submucosal Ganglia in Colonic Inertia.

Science.gov (United States)

Naemi, Kaveh; Stamos, Michael J; Wu, Mark Li-Cheng

2018-02-01

- Colonic inertia is a debilitating form of primary chronic constipation with unknown etiology and diagnostic criteria, often requiring pancolectomy. We have occasionally observed massively enlarged submucosal ganglia containing at least 20 perikarya, in addition to previously described giant ganglia with greater than 8 perikarya, in cases of colonic inertia. These massively enlarged ganglia have yet to be formally recognized. - To determine whether such "massive submucosal ganglia," defined as ganglia harboring at least 20 perikarya, characterize colonic inertia. - We retrospectively reviewed specimens from colectomies of patients with colonic inertia and compared the prevalence of massive submucosal ganglia occurring in this setting to the prevalence of massive submucosal ganglia occurring in a set of control specimens from patients lacking chronic constipation. - Seven of 8 specimens affected by colonic inertia harbored 1 to 4 massive ganglia, for a total of 11 massive ganglia. One specimen lacked massive ganglia but had limited sampling and nearly massive ganglia. Massive ganglia occupied both superficial and deep submucosal plexus. The patient with 4 massive ganglia also had 1 mitotically active giant ganglion. Only 1 massive ganglion occupied the entire set of 10 specimens from patients lacking chronic constipation. - We performed the first, albeit distinctly small, study of massive submucosal ganglia and showed that massive ganglia may be linked to colonic inertia. Further, larger studies are necessary to determine whether massive ganglia are pathogenetic or secondary phenomena, and whether massive ganglia or mitotically active ganglia distinguish colonic inertia from other types of chronic constipation.

Lessons Learned from resolving massive IPS database change for SPADES+

Energy Technology Data Exchange (ETDEWEB)

Kim, Jin-Soo [KEPCO Engineering and Construction Co., Deajeon (Korea, Republic of)

2016-10-15

Safety Parameter Display and Evaluation System+ (SPADES+) was implemented to meet the requirements for Safety Parameter Display System (SPDS) which are related to TMI Action Plan requirements. SPADES+ monitors continuously the critical safety function during normal, abnormal, and emergency operation mode and generates the alarm output to the alarm server when the tolerance related to safety functions are not satisfied. The alarm algorithm for critical safety function is performed in the NSSS Application Software (NAPS) server of the Information Process System (IPS) and the calculation result will be displayed on the flat panel display (FPD) of the IPS. SPADES+ provides the critical variable to the control room operators to aid them in rapidly and reliable determining the safety status of the plant. Many database point ID names (518 points) were changed. POINT{sub I}D is used in the programming source code, the related documents such as SDS and SRS, and Graphic database. To reduce human errors, computer program and office program’s Macro are used. Though the automatic methods are used for changing POINT{sub I}Ds, it takes lots of time to resolve for editing the change list except for making computerized solutions. In IPS, there are many more programs than SPADES+ and over 30,000 POINT{sub I}Ds are in IPS database. Changing POINT{sub I}Ds could be a burden to software engineers. In case of Ovation system database, there is the Alias field to prevent this kind of problem. The Alias is a kind of secondary key in database.

New massive gravity

NARCIS (Netherlands)

Bergshoeff, Eric A.; Hohm, Olaf; Townsend, Paul K.

2012-01-01

We present a brief review of New Massive Gravity, which is a unitary theory of massive gravitons in three dimensions obtained by considering a particular combination of the Einstein-Hilbert and curvature squared terms.

The watercolor effect: quantitative evidence for luminance-dependent mechanisms of long-range color assimilation.

Science.gov (United States)

Devinck, Frédéric; Delahunt, Peter B; Hardy, Joseph L; Spillmann, Lothar; Werner, John S

2005-05-01

When a dark chromatic contour delineating a figure is flanked on the inside by a brighter chromatic contour, the brighter color will spread into the entire enclosed area. This is known as the watercolor effect (WCE). Here we quantified the effect of color spreading using both color-matching and hue-cancellation tasks. Over a wide range of stimulus chromaticities, there was a reliable shift in color appearance that closely followed the direction of the inducing contour. When the contours were equated in luminance, the WCE was still present, but weak. The magnitude of the color spreading increased with increases in luminance contrast between the two contours. Additionally, as the luminance contrast between the contours increased, the chromaticity of the induced color more closely resembled that of the inside contour. The results support the hypothesis that the WCE is mediated by luminance-dependent mechanisms of long-range color assimilation.

Luminal and basolateral uptake of insulin in isolated perfused, proximal tubules

International Nuclear Information System (INIS)

Nielsen, S.; Nielsen, J.T.; Christensen, E.I.

1987-01-01

The present study was performed to quantitate compare the luminal and the peritubular uptake of 125 I-insulin in isolated, perfused, proximal tubules from rabbit kidneys. 125 I-insulin was added in physiological concentrations to either the perfusate or the bath fluid for 30 min. The luminal uptake in 30 min averaged 0.76 pg/mm at physiological concentrations and 18.0 pg/mm at high insulin concentrations. About 15-41% of the absorbed insulin was digested and 125 I-insulin at physiological and high concentrations in the bath was 0.136 and 0.318 pg, respectively. The data indicates that insulin is bound/absorbed at the basolateral membranes both by a saturable specific mechanism and a nonspecific, nonsaturable mechanism. The basolateral absorption constituted 15.2 and 1.8% of the total tubular extraction of insulin at physiological and high insulin concentrations, respectively. Electron microscope autoradiography showed that, after luminal as well as basolateral endocytosis, insulin was exclusively accumulated in endocytic vacuoles and lysosomes

Optimal combination of illusory and luminance-defined 3-D surfaces: A role for ambiguity.

Science.gov (United States)

Hartle, Brittney; Wilcox, Laurie M; Murray, Richard F

2018-04-01

The shape of the illusory surface in stereoscopic Kanizsa figures is determined by the interpolation of depth from the luminance edges of adjacent inducing elements. Despite ambiguity in the position of illusory boundaries, observers reliably perceive a coherent three-dimensional (3-D) surface. However, this ambiguity may contribute additional uncertainty to the depth percept beyond what is expected from measurement noise alone. We evaluated the intrinsic ambiguity of illusory boundaries by using a cue-combination paradigm to measure the reliability of depth percepts elicited by stereoscopic illusory surfaces. We assessed the accuracy and precision of depth percepts using 3-D Kanizsa figures relative to luminance-defined surfaces. The location of the surface peak was defined by illusory boundaries, luminance-defined edges, or both. Accuracy and precision were assessed using a depth-discrimination paradigm. A maximum likelihood linear cue combination model was used to evaluate the relative contribution of illusory and luminance-defined signals to the perceived depth of the combined surface. Our analysis showed that the standard deviation of depth estimates was consistent with an optimal cue combination model, but the points of subjective equality indicated that observers consistently underweighted the contribution of illusory boundaries. This systematic underweighting may reflect a combination rule that attributes additional intrinsic ambiguity to the location of the illusory boundary. Although previous studies show that illusory and luminance-defined contours share many perceptual similarities, our model suggests that ambiguity plays a larger role in the perceptual representation of illusory contours than of luminance-defined contours.

STABLE ISOTOPE GEOCHEMISTRY OF MASSIVE ICE

Directory of Open Access Journals (Sweden)

Yurij K. Vasil’chuk

2016-01-01

Full Text Available The paper summarises stable-isotope research on massive ice in the Russian and North American Arctic, and includes the latest understanding of massive-ice formation. A new classification of massive-ice complexes is proposed, encompassing the range and variabilityof massive ice. It distinguishes two new categories of massive-ice complexes: homogeneousmassive-ice complexes have a similar structure, properties and genesis throughout, whereasheterogeneous massive-ice complexes vary spatially (in their structure and properties andgenetically within a locality and consist of two or more homogeneous massive-ice bodies.Analysis of pollen and spores in massive ice from Subarctic regions and from ice and snow cover of Arctic ice caps assists with interpretation of the origin of massive ice. Radiocarbon ages of massive ice and host sediments are considered together with isotope values of heavy oxygen and deuterium from massive ice plotted at a uniform scale in order to assist interpretation and correlation of the ice.

Prognostic Significance of Progesterone Receptor–Positive Tumor Cells Within Immunohistochemically Defined Luminal A Breast Cancer

Science.gov (United States)

Prat, Aleix; Cheang, Maggie Chon U.; Martín, Miguel; Parker, Joel S.; Carrasco, Eva; Caballero, Rosalía; Tyldesley, Scott; Gelmon, Karen; Bernard, Philip S.; Nielsen, Torsten O.; Perou, Charles M.

2013-01-01

Purpose Current immunohistochemical (IHC)-based definitions of luminal A and B breast cancers are imperfect when compared with multigene expression-based assays. In this study, we sought to improve the IHC subtyping by examining the pathologic and gene expression characteristics of genomically defined luminal A and B subtypes. Patients and Methods Gene expression and pathologic features were collected from primary tumors across five independent cohorts: British Columbia Cancer Agency (BCCA) tamoxifen-treated only, Grupo Español de Investigación en Cáncer de Mama 9906 trial, BCCA no systemic treatment cohort, PAM50 microarray training data set, and a combined publicly available microarray data set. Optimal cutoffs of percentage of progesterone receptor (PR) –positive tumor cells to predict survival were derived and independently tested. Multivariable Cox models were used to test the prognostic significance. Results Clinicopathologic comparisons among luminal A and B subtypes consistently identified higher rates of PR positivity, human epidermal growth factor receptor 2 (HER2) negativity, and histologic grade 1 in luminal A tumors. Quantitative PR gene and protein expression were also found to be significantly higher in luminal A tumors. An empiric cutoff of more than 20% of PR-positive tumor cells was statistically chosen and proved significant for predicting survival differences within IHC-defined luminal A tumors independently of endocrine therapy administration. Finally, no additional prognostic value within hormonal receptor (HR) –positive/HER2-negative disease was observed with the use of the IHC4 score when intrinsic IHC-based subtypes were used that included the more than 20% PR-positive tumor cells and vice versa. Conclusion Semiquantitative IHC expression of PR adds prognostic value within the current IHC-based luminal A definition by improving the identification of good outcome breast cancers. The new proposed IHC-based definition of luminal A

Histone 2B-GFP Label-Retaining Prostate Luminal Cells Possess Progenitor Cell Properties and Are Intrinsically Resistant to Castration

Directory of Open Access Journals (Sweden)

Dingxiao Zhang

2018-01-01

Full Text Available The existence of slow-cycling luminal cells in the prostate has been suggested, but their identity and functional properties remain unknown. Using a bigenic mouse model to earmark, isolate, and characterize the quiescent stem-like cells, we identify a label-retaining cell (LRC population in the luminal cell layer as luminal progenitors. Molecular and biological characterizations show that these luminal LRCs are significantly enriched in the mouse proximal prostate, exhibit relative dormancy, display bipotency in both in vitro and in vivo assays, and express a stem/progenitor gene signature with resemblance to aggressive prostate cancer. Importantly, these LRCs, compared with bulk luminal cells, maintain a lower level of androgen receptor (AR expression and are less androgen dependent and also castration resistant in vivo. Finally, analysis of phenotypic markers reveals heterogeneity within the luminal progenitor cell pool. Our study establishes luminal LRCs as progenitors that may serve as a cellular origin for castration-resistant prostate cancer.

Massive graviton geons

Science.gov (United States)

Aoki, Katsuki; Maeda, Kei-ichi; Misonoh, Yosuke; Okawa, Hirotada

2018-02-01

We find vacuum solutions such that massive gravitons are confined in a local spacetime region by their gravitational energy in asymptotically flat spacetimes in the context of the bigravity theory. We call such self-gravitating objects massive graviton geons. The basic equations can be reduced to the Schrödinger-Poisson equations with the tensor "wave function" in the Newtonian limit. We obtain a nonspherically symmetric solution with j =2 , ℓ=0 as well as a spherically symmetric solution with j =0 , ℓ=2 in this system where j is the total angular momentum quantum number and ℓ is the orbital angular momentum quantum number, respectively. The energy eigenvalue of the Schrödinger equation in the nonspherical solution is smaller than that in the spherical solution. We then study the perturbative stability of the spherical solution and find that there is an unstable mode in the quadrupole mode perturbations which may be interpreted as the transition mode to the nonspherical solution. The results suggest that the nonspherically symmetric solution is the ground state of the massive graviton geon. The massive graviton geons may decay in time due to emissions of gravitational waves but this timescale can be quite long when the massive gravitons are nonrelativistic and then the geons can be long-lived. We also argue possible prospects of the massive graviton geons: applications to the ultralight dark matter scenario, nonlinear (in)stability of the Minkowski spacetime, and a quantum transition of the spacetime.

Defining optimal duration and predicting benefit from chemotherapy in patients with luminal-like subtypes.

Science.gov (United States)

Hart, Christopher D; Sanna, Giuseppina; Siclari, Olimpia; Biganzoli, Laura; Di Leo, Angelo

2015-11-01

The molecular subtypes of breast cancer have individual patterns of behaviour, prognosis and sensitivity to treatment, with subsequent implications for the choice of, or indeed role for adjuvant therapy. The luminal A and B subtypes make up the majority of breast cancers, but despite sharing expression of the oestrogen receptor (ER), they are molecularly distinct. It follows then that they would have different sensitivities to chemotherapy. Clinically, luminal A disease has a better prognosis than luminal B, and may not derive significant benefit from adjuvant chemotherapy. However no prospective trials have specifically investigated the benefit of adjuvant chemotherapy in each subtype, nor do we know if certain agents are more or less effective. This paper will briefly summarise the role of molecular profiles in assessing the need for chemotherapy and predicting its effectiveness, followed by an assessment of the relative value of newer anthracycline- or taxane-containing regimes in the luminal-like subtypes, providing a review of retrospective analyses. Copyright © 2015 Elsevier Ltd. All rights reserved.

10 CFR 30.19 - Self-luminous products containing tritium, krypton-85, or promethium-147.

Science.gov (United States)

2010-01-01

... 10 Energy 1 2010-01-01 2010-01-01 false Self-luminous products containing tritium, krypton-85, or..., krypton-85, or promethium-147. (a) Except for persons who manufacture, process, produce, or initially transfer for sale or distribution self-luminous products containing tritium, krypton-85, or promethium-147...

Galaxy growth in a massive halo in the first billion years of cosmic history

Science.gov (United States)

Marrone, D. P.; Spilker, J. S.; Hayward, C. C.; Vieira, J. D.; Aravena, M.; Ashby, M. L. N.; Bayliss, M. B.; Béthermin, M.; Brodwin, M.; Bothwell, M. S.; Carlstrom, J. E.; Chapman, S. C.; Chen, Chian-Chou; Crawford, T. M.; Cunningham, D. J. M.; De Breuck, C.; Fassnacht, C. D.; Gonzalez, A. H.; Greve, T. R.; Hezaveh, Y. D.; Lacaille, K.; Litke, K. C.; Lower, S.; Ma, J.; Malkan, M.; Miller, T. B.; Morningstar, W. R.; Murphy, E. J.; Narayanan, D.; Phadke, K. A.; Rotermund, K. M.; Sreevani, J.; Stalder, B.; Stark, A. A.; Strandet, M. L.; Tang, M.; Weiß, A.

2018-01-01

According to the current understanding of cosmic structure formation, the precursors of the most massive structures in the Universe began to form shortly after the Big Bang, in regions corresponding to the largest fluctuations in the cosmic density field. Observing these structures during their period of active growth and assembly—the first few hundred million years of the Universe—is challenging because it requires surveys that are sensitive enough to detect the distant galaxies that act as signposts for these structures and wide enough to capture the rarest objects. As a result, very few such objects have been detected so far. Here we report observations of a far-infrared-luminous object at redshift 6.900 (less than 800 million years after the Big Bang) that was discovered in a wide-field survey. High-resolution imaging shows it to be a pair of extremely massive star-forming galaxies. The larger is forming stars at a rate of 2,900 solar masses per year, contains 270 billion solar masses of gas and 2.5 billion solar masses of dust, and is more massive than any other known object at a redshift of more than 6. Its rapid star formation is probably triggered by its companion galaxy at a projected separation of 8 kiloparsecs. This merging companion hosts 35 billion solar masses of stars and has a star-formation rate of 540 solar masses per year, but has an order of magnitude less gas and dust than its neighbour and physical conditions akin to those observed in lower-metallicity galaxies in the nearby Universe. These objects suggest the presence of a dark-matter halo with a mass of more than 100 billion solar masses, making it among the rarest dark-matter haloes that should exist in the Universe at this epoch.

High luminous flux from single crystal phosphor-converted laser-based white lighting system

KAUST Repository

Cantore, Michael; Pfaff, Nathan; Farrell, Robert M.; Speck, James S.; Nakamura, Shuji; DenBaars, Steven P.

2015-01-01

efficacy of 86.7 lm/W at 1.4 A and 4.24 V and a peak luminous flux of 1100 lm at 3.0 A and 4.85 V with a luminous efficacy of 75.6 lm/W. Simulations of a pc-LD confirm that the single crystal YAG:Ce sample did not experience thermal quenching at peak LD

Production of L-Asparaginase by the marine luminous bacteria

Digital Repository Service at National Institute of Oceanography (India)

Ramaiah, N.; Chandramohan, D.

Fortythree strains of luminous bacteria, belonging to 4 species, (Vibrio harveyi, V. fischeri, Photobacterium leiognathi and P. phosphoreum) isolated from different marine samples, were examined for the production of L-asparaginase. Presence...

Method and apparatus for generating highly luminous flame

Energy Technology Data Exchange (ETDEWEB)

Gitman, G.M.

1992-05-12

A combustion process and apparatus are provided for generating a variable high temperature, highly luminous flame with low NOx emission by burning gaseous and liquid materials with oxygen and air. More particularly, the invention provides a process in which there is initial control of fuel, oxygen, and air flows and the delivery of the oxidizers to a burner as two oxidizing gases having different oxygen concentrations (for example, pure oxygen and air, or oxygen and oxygen-enriched air). A first oxidizing gas containing a high oxygen concentration is injected as a stream into the central zone of a combustion tunnel or chamber, and part of the fuel (preferably the major part) is injected into the central pyrolysis zone to mix with the first oxidizing gas to create a highly luminous high-temperature flame core containing microparticles of carbon of the proper size for maximum luminosity and high temperature, and a relatively small amount of hydrocarbon radicals. In addition, part of the fuel (preferably the minor part) is injected in a plurality of streams about the flame core to mix with a second oxidizing gas (containing a lower oxygen concentration than the first oxidizing gas) and injecting the second oxidizing mixture about the flame core and the minor fuel flow to mix with the minor fuel flow. This creates a plurality of fuel-lean (oxygen-rich) flames which are directed toward the luminous flame core to form a final flame pattern having high temperature, high luminosity, and low NOx content. 6 figs.

Effect of luminance contrast on BOLD-fMRI response in deaf and normal occipital visual cortex

International Nuclear Information System (INIS)

Xue Yanping; Zhai Renyou; Jiang Tao; Cui Yong; Zhou Tiangang; Rao Hengyi; Zhuo Yan

2002-01-01

Objective: To examine the effect of luminance contrast stimulus by using blood oxygenation level dependent functional magnetic resonance imaging (BOLD-fMRI) within deaf occipital visual cortex, and to compare the distribution, extent, and intensity of activated areas between deaf subjects and normal hearing subjects. Methods: Twelve deaf subjects (average age 16.5) and 15 normal hearing subjects (average age 23.7) were stimulated by 4 kinds of luminance contrast (0.7, 2.2, 50.0, 180.0 lm). The fMRI data were collected on GE 1.5 T Signa Horizon LX MRI system and analyzed by AFNI to generate the activation map. Results: Responding to all 4 kinds of stimulus luminance contrast, all deaf and normal subjects showed significant activations in occipital visual cortex. For both deaf and normal subjects, the number of activated pixels increased significantly with increasing luminance contrast (F normal = 4.27, P deaf = 6.41, P 0.05). The local mean activation level for all activated pixels remained constant with increasing luminance contrast. However, there was an increase in the mean activation level for those activated pixels common to all trials as the stimulus luminance contrast was increased, but no significant difference was found within them (F normal = 0.79, P > 0.05; F deaf = 1.6, P > 0.05). Conclusion: The effect of luminance contrast on occipital visual cortex of deaf is similar to but somewhat higher than that of normal hearing subjects. In addition, it also proved that fMRI is a feasible method in the study of the deaf visual cortex

Relation between acid back-diffusion and luminal surface hydrophobicity in canine gastric mucosa: Effects of salicylate and prostaglandin

International Nuclear Information System (INIS)

Goddard, P.J.

1989-01-01

The stomach is thought to be protected from luminal acid by a gastric mucosal barrier that restricts the diffusion of acid into tissue. This study tested the hypothesis that the hydrophobic luminal surface of canine gastric mucosa incubated in Ussing chambers, impedes the back-diffusion of luminal acid into the tissue. Isolated sheets of mucosa were treated with cimetidine to inhibit spontaneous acid secretion, and incubated under conditions that prevented significant secretion of luminal bicarbonate. By measuring acid loss from the luminal compartment using the pH-stat technique, acid back-diffusion was continuously monitored; potential difference (PD) was measured as an index of tissue viability. Tissue luminal surface hydrophobicity was estimated by contact angle analysis at the end of each experiment. Addition of 16,16-dimethyl prostaglandin E 2 to the nutrient compartment enhanced luminal surface hydrophobicity, but did not reduce acid back-diffusion in tissues that maintained a constant PD. 10 mM salicylate at pH 4.00 in the luminal compartment reduced surface hydrophobicity, but this decrease did not occur if 1 ug/ml prostaglandin was present in the nutrient solution. Despite possessing relatively hydrophilic and relatively hydrophobic surface properties, respectively, acid back-diffusion in the absence of salicylate was not significantly different between these two groups. Neither group maintained a PD after incubation with salicylate. Lastly, radiolabeled salicylate was used to calculate the free (non-salicylate associated) acid loss in tissues incubated with salicylate and/or prostaglandin. No significant correlation was found between free acid back-diffusion and luminal surface hydrophobicity. These data do not support the hypothesis that acid back-diffusion in impeded by the hydrophobic surface presented by isolated canine gastric mucosa

High-Risk Premenopausal Luminal A Breast Cancer Patients Derive no Benefit from Adjuvant Cyclophosphamide-based Chemotherapy

DEFF Research Database (Denmark)

Nielsen, Torsten O; Jensen, Maj-Brit; Burugu, Samantha

2017-01-01

Purpose: Luminal A breast cancers have better prognosis than other molecular subtypes. Luminal A cancers may also be insensitive to adjuvant chemotherapy, although there is little high-level evidence to confirm this concept. The primary hypothesis in this formal prospective-retrospective analysis...... was to assess interaction between subtype (Luminal A vs. other) and treatment (chemotherapy vs. not) for the primary endpoint (10-year invasive disease-free survival) of a breast cancer trial randomizing women to adjuvant chemotherapy, analyzed in multivariate Cox proportional hazards models using the Wald...... interval (CI), 0.53-2.14; P = 0.86], whereas patients with non-luminal A subtypes did (HR, 0.50; 95% CI, 0.38-0.66; P breast cancers did not benefit from adjuvant...

The Atacama Cosmology Telescope: ACT-CL J0102-4215 "El Gordo," a Massive Merging Cluster at Redshift 0.87

Science.gov (United States)

Menanteau, Felipe; Hughes, John Pl; Baker, Andrew J.; Sifon, Cristobal; Gonzalez, Jorge; Infante, Leopoldo; Barrientos, L. Felipe; Hilton, Matt; Das, Sudeep; Spergel, David N.;

A massive, dead disk galaxy in the early Universe.

Science.gov (United States)

Toft, Sune; Zabl, Johannes; Richard, Johan; Gallazzi, Anna; Zibetti, Stefano; Prescott, Moire; Grillo, Claudio; Man, Allison W S; Lee, Nicholas Y; Gómez-Guijarro, Carlos; Stockmann, Mikkel; Magdis, Georgios; Steinhardt, Charles L

2017-06-21

At redshift z = 2, when the Universe was just three billion years old, half of the most massive galaxies were extremely compact and had already exhausted their fuel for star formation. It is believed that they were formed in intense nuclear starbursts and that they ultimately grew into the most massive local elliptical galaxies seen today, through mergers with minor companions, but validating this picture requires higher-resolution observations of their centres than is currently possible. Magnification from gravitational lensing offers an opportunity to resolve the inner regions of galaxies. Here we report an analysis of the stellar populations and kinematics of a lensed z = 2.1478 compact galaxy, which-surprisingly-turns out to be a fast-spinning, rotationally supported disk galaxy. Its stars must have formed in a disk, rather than in a merger-driven nuclear starburst. The galaxy was probably fed by streams of cold gas, which were able to penetrate the hot halo gas until they were cut off by shock heating from the dark matter halo. This result confirms previous indirect indications that the first galaxies to cease star formation must have gone through major changes not just in their structure, but also in their kinematics, to evolve into present-day elliptical galaxies.

Environmental radioactive monitoring, evaluation and protection in luminous workshops of a factory

International Nuclear Information System (INIS)

Dai Hanbin; Xiang Ming; Tan Jianzu

2009-01-01

Fluorescent technique is often used to display instrumental indicator in the dark environment. Luminous workshops of a factory smear and depict the glassware by means of fluorescent power with adulterated radioactive matter. Because of adulterated radioactive matters such as 226 Ra, 40 K emit alpha-ray,beta-ray and gamma-ray, while they decay spontaneously, and high dose or cumulative radiation can damage human body in different degrees. Therefore, any radioactive damage to human body caused by over-safety dose should be prevented strictly during the working. To ensure health and safety of working staff in luminous workshop and the public, it is necessary to regularly have radioactive monitoring and evaluation to luminous workshop and its surrounding environment. Through the environment radioactive monitoring, the authors analyze its environmental radioactive level,and try to find out the possible problems so as to propose some protective measures for personal health. (authors)

Hard X-ray emission of the luminous infrared galaxy NGC 6240 as observed by NuSTAR

Science.gov (United States)

Puccetti, S.; Comastri, A.; Bauer, F. E.; Brandt, W. N.; Fiore, F.; Harrison, F. A.; Luo, B.; Stern, D.; Urry, C. M.; Alexander, D. M.; Annuar, A.; Arévalo, P.; Baloković, M.; Boggs, S. E.; Brightman, M.; Christensen, F. E.; Craig, W. W.; Gandhi, P.; Hailey, C. J.; Koss, M. J.; La Massa, S.; Marinucci, A.; Ricci, C.; Walton, D. J.; Zappacosta, L.; Zhang, W.

2016-01-01

We present a broadband (~0.3-70 keV) spectral and temporal analysis of NuSTAR observations of the luminous infrared galaxy NGC 6240 combined with archival Chandra, XMM-Newton, and BeppoSAX data. NGC 6240 is a galaxy in a relatively early merger state with two distinct nuclei separated by ~1.̋5. Previous Chandra observations resolved the two nuclei and showed that they are both active and obscured by Compton-thick material. Although they cannot be resolved by NuSTAR, we were able to clearly detect, for the first time, both the primary and the reflection continuum components thanks to the unprecedented quality of the NuSTAR data at energies >10 keV. The NuSTAR hard X-ray spectrum is dominated by the primary continuum piercing through an absorbing column density which is mildly optically thick to Compton scattering (τ ≃ 1.2, NH ~ 1.5 × 1024 cm-2). We detect moderately hard X-ray (>10 keV) flux variability up to 20% on short (15-20 ks) timescales. The amplitude of the variability is largest at ~30 keV and is likely to originate from the primary continuum of the southern nucleus. Nevertheless, the mean hard X-ray flux on longer timescales (years) is relatively constant. Moreover, the two nuclei remain Compton-thick, although we find evidence of variability in the material along the line of sight with column densities NH ≤ 2 × 1023 cm-2 over long (~3-15 yr) timescales. The observed X-ray emission in the NuSTAR energy range is fully consistent with the sum of the best-fit models of the spatially resolved Chandra spectra of the two nuclei.

Night sky luminance under clear sky conditions: Theory vs. experiment

International Nuclear Information System (INIS)

Kocifaj, Miroslav

2014-01-01

Sky glow is caused by both natural phenomena and factors of anthropogenic origin, and of the latter ground-based light sources are the most important contributors for they emit the spatially linked spectral radiant intensity distribution of artificial light sources, which are further modulated by local atmospheric optics and perceived as the diffuse light of a night sky. In other words, sky glow is closely related to a city's shape and pattern of luminaire distribution, in practical effect an almost arbitrary deployment of random orientation of heterogeneous electrical light sources. Thus the luminance gradation function measured in a suburban zone or near the edges of a city is linked to the City Pattern or vice versa. It is shown that clear sky luminance/radiance data recorded in an urban area can be used to retrieve the bulk luminous/radiant intensity distribution if some a-priori information on atmospheric aerosols is available. For instance, the single scattering albedo of aerosol particles is required under low turbidity conditions, as demonstrated on a targeted experiment in the city of Frýdek-Mistek. One of the main advantages of the retrieval method presented in this paper is that the single scattering approximation is satisfactorily accurate in characterizing the light field near the ground because the dominant contribution to the sky glow has originated from beams propagated along short optical paths. - Highlights: • Urban sky glow is interpreted in terms of city emission function. • Luminance function in a suburban zone is linked to the City Pattern. • Single scattering approximation is applicable in modeling urban sky glow. • Information on aerosols represents valuable inputs to the retrieval procedure. • Sky glow patterns vary with light source distribution and spectral emission

Luminal flow amplifies stent-based drug deposition in arterial bifurcations.

Directory of Open Access Journals (Sweden)

Vijaya B Kolachalama

2009-12-01

Full Text Available Treatment of arterial bifurcation lesions using drug-eluting stents (DES is now common clinical practice and yet the mechanisms governing drug distribution in these complex morphologies are incompletely understood. It is still not evident how to efficiently determine the efficacy of local drug delivery and quantify zones of excessive drug that are harbingers of vascular toxicity and thrombosis, and areas of depletion that are associated with tissue overgrowth and luminal re-narrowing.We constructed two-phase computational models of stent-deployed arterial bifurcations simulating blood flow and drug transport to investigate the factors modulating drug distribution when the main-branch (MB was treated using a DES. Simulations predicted extensive flow-mediated drug delivery in bifurcated vascular beds where the drug distribution patterns are heterogeneous and sensitive to relative stent position and luminal flow. A single DES in the MB coupled with large retrograde luminal flow on the lateral wall of the side-branch (SB can provide drug deposition on the SB lumen-wall interface, except when the MB stent is downstream of the SB flow divider. In an even more dramatic fashion, the presence of the SB affects drug distribution in the stented MB. Here fluid mechanic effects play an even greater role than in the SB especially when the DES is across and downstream to the flow divider and in a manner dependent upon the Reynolds number.The flow effects on drug deposition and subsequent uptake from endovascular DES are amplified in bifurcation lesions. When only one branch is stented, a complex interplay occurs - drug deposition in the stented MB is altered by the flow divider imposed by the SB and in the SB by the presence of a DES in the MB. The use of DES in arterial bifurcations requires a complex calculus that balances vascular and stent geometry as well as luminal flow.

Virulence of luminous vibrios to Artemia franciscana nauplii.

Science.gov (United States)

Soto-Rodriguez, S A; Roque, A; Lizarraga-Partida, M L; Guerra-Flores, A L; Gomez-Gill, B

2003-02-27

From healthy and diseased penaeid shrimp from Asia and the Americas, 25 luminous and 2 non-luminous bacterial strains were isolated, and 14 were phenotypically identified as Vibrio harveyi; 9 isolates produced significant mortalities (45 to 80%) in Artemia franciscana nauplii at inoculation densities of 10(5) to 10(6) CFU ml(-1) compared to the controls (unchallenged nauplii). The maximum number of bacteria ingested (bioencapsulated) by the Artemia nauplii varied from less than 10 to 10(3) CFU nauplius(-1) and no significant relationship was observed between the density of bacteria inoculated, the amount of bacteria ingested, and naupliar mortality. Significant correlations were obtained between naupliar mortality and production of proteases, phospholipases or siderophores, but not between mortality and lipase production, gelatinase production, hydrophobicity or hemolytic activity. The results suggest that virulence of the strains tested was more related to the production of particular exoenzymes than to the measured colonization factors.

Conservatively treated massive prolapsed discs: a 7-year follow-up

Science.gov (United States)

Benson, RT; Tavares, SP; Robertson, SC; Sharp, R; Marshall, RW

2010-01-01

INTRODUCTION The natural history of a lumbar hernia of the nucleus pulposus (HNP) is not fully known and clear indications for operative intervention cannot be established from the literature. Several studies have shown that the largest discs appear to have the greatest tendency to resolve. The aim of this study was to investigate whether massive prolapsed discs can be safely managed conservatively once clinical improvement has occurred. PATIENTS AND METHODS Thirty-seven patients were studied by clinical assessments and serial magnetic resonance imaging (MRI) over 2 years. Patients had severe sciatica at first, but began to show clinical improvement despite the large disc hernia-tions. Clinical assessment included the Lasegue test and neurological appraisal. The Oswestry Disability Index was used to measure function and changes in function. Serial MRI studies allowed measurement of volume changes of the herniated disc material over a period of time. RESULTS Initial follow-up at an average of 23.2 months revealed that 83% had a complete and sustained recovery at the initial follow-up. Only four patients required a discectomy. The average Oswestry disability index improved from 58% to 15%. Volumetric analysis of serial MRI scans found an average reduction of 64% in disc size. There was a poor correlation between clinical improvement and the extent of disc resolution. CONCLUSIONS A massive disc herniation can pursue a favourable clinical course. If early progress is shown, the long-term prognosis is very good and even massive disc herniations can be treated conservatively. PMID:19887021

The CGM of Massive Galaxies: Where Cold Gas Goes to Die?

Science.gov (United States)

Howk, Jay

2017-08-01

We propose to survey the cold HI content and metallicity of the circumgalactic medium (CGM) around 50 (45 new, 5 archival) z 0.5 Luminous Red Galaxies (LRGs) to directly test a fundamental prediction of galaxy assembly models: that cold, metal-poor accretion does not survive to the inner halos of very massive galaxies. Accretion and feedback through the CGM play key roles in our models of the star formation dichotomy in galaxies. Low mass galaxies are thought to accrete gas in cold streams, while high mass galaxies host hot, dense halos that heat incoming gas and prevent its cooling, thereby quenching star formation. HST/COS has provided evidence for cold, metal-poor streams in the halos of star-forming galaxies (consistent with cold accretion). Observations have also demonstrated the presence of cool gas in the halos of passive galaxies, a potential challenge to the cold/hot accretion model. Our proposed observations will target the most massive galaxies and address the origin of the cool CGM gas by measuring the metallicity. This experiment is enabled by our novel approach to deriving metallicities, allowing the use of much fainter QSOs. It cannot be done with archival data, as these rare systems are not often probed along random sight lines. The H I column density (and metallicity) measurements require access to the UV. The large size of our survey is crucial to robustly assess whether the CGM in these galaxies is unique from that of star-forming systems, a comparison that provides the most stringent test of cold-mode accretion/quenching models to date. Conversely, widespread detections of metal-poor gas in these halos will seriously challenge the prevailing theory.

What causes IOR? Attention or perception? - manipulating cue and target luminance in either blocked or mixed condition.

Science.gov (United States)

Zhao, Yuanyuan; Heinke, Dietmar

2014-12-01

Inhibition of return (IOR) refers to the performance disadvantage when detecting a target presented at a previously cued location. The current paper contributes to the long-standing debate whether IOR is caused by attentional processing or perceptual processing. We present a series of four experiments which varied the cue luminance in mixed and blocked conditions. We hypothesised that if inhibition was initialized by an attentional process the size of IOR should not vary in the blocked condition as participants should be able to adapt to the level of cue luminance. However, if a perceptual process triggers inhibition both experimental manipulations should lead to varying levels of IOR. Indeed, we found evidence for the latter hypothesis. In addition, we also varied the target luminance in blocked and mixed condition. Both manipulations, cue luminance and target luminance, affected IOR in an additive fashion suggesting that the two stimuli affect human behaviour on different processing stages. Copyright © 2014 Elsevier Ltd. All rights reserved.

Contribution of a luminance-dependent S-cone mechanism to non-assimilative color spreading in the watercolor configuration

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Eiji eKimura

2014-12-01

Full Text Available In the watercolor configuration composed of wavy double contours, both assimilative and non-assimilative color spreading have been demonstrated depending on the luminance conditions of the inner and outer contours (IC and OC, respectively. This study investigated how the induced color in the watercolor configuration was modulated by combinations of the IC and the OC color, particularly addressing non-assimilative color spreading. In two experiments, the IC color was fixed to a certain color and combined with various colors selected from a hue circle centered at the background white color. Color spreading was quantified with a chromatic cancellation technique. Results showed that both the magnitude and the apparent hue of the color spreading were largely changed with the luminance condition. When the IC contrast (Weber contrast of the IC to the background luminance was smaller in size than the OC contrast (higher IC luminance condition, the color spreading was assimilative. When the luminance condition was reversed and the IC contrast was greater than the OC contrast (lower IC luminance condition, the color spreading was non-assimilative and yellowish. When the color spreading was analyzed in terms of cone-opponent excitations, the results were consistent with the interpretation that the color spreading is explainable by a combination of chromatic diffusion from the IC and chromatically opponent induction from the OC. The color spreading in the higher IC luminance condition mainly reflected the chromatic diffusion by both (L–M and S cone-opponent mechanisms. The non-assimilative color spreading in the lower IC luminance condition mostly reflected S-cone mediated opponent induction and the contribution of -S inducing mechanisms was differentially large. These findings provided several constraints on possible visual mechanisms underlying the watercolor effect.

Contribution of a luminance-dependent S-cone mechanism to non-assimilative color spreading in the watercolor configuration.

Science.gov (United States)

Kimura, Eiji; Kuroki, Mikako

2014-01-01

In the watercolor configuration composed of wavy double contours, both assimilative and non-assimilative color spreading have been demonstrated depending on the luminance conditions of the inner and outer contours (IC and OC, respectively). This study investigated how the induced color in the watercolor configuration was modulated by combinations of the IC and the OC color, particularly addressing non-assimilative color spreading. In two experiments, the IC color was fixed to a certain color and combined with various colors selected from a hue circle centered at the background white color. Color spreading was quantified with a chromatic cancelation technique. Results showed that both the magnitude and the apparent hue of the color spreading were largely changed with the luminance condition. When the IC contrast (Weber contrast of the IC to the background luminance) was smaller in size than the OC contrast (higher IC luminance condition), the color spreading was assimilative. When the luminance condition was reversed and the IC contrast was greater than the OC contrast (lower IC luminance condition), the color spreading was non-assimilative and yellowish. When the color spreading was analyzed in terms of cone-opponent excitations, the results were consistent with the interpretation that the color spreading is explainable by a combination of chromatic diffusion from the IC and chromatically opponent induction from the OC. The color spreading in the higher IC luminance condition mainly reflected the chromatic diffusion by both (L-M) and S cone-opponent mechanisms. The non-assimilative color spreading in the lower IC luminance condition mostly reflected S-cone mediated opponent induction and the contribution of -S inducing mechanisms was differentially large. These findings provided several constraints on possible visual mechanisms underlying the watercolor effect.

Immunohistochemical localisation of keratin and luminal epithelial antigen in myoepithelial and luminal epithelial cells of human mammary and salivary gland tumours.

Science.gov (United States)

Nathrath, W B; Wilson, P D; Trejdosiewicz, L K

1982-01-01

Rabbit antisera to human 40-63 000 MW epidermal keratin, one batch with restricted distribution of reactivity from an initial (aK1) and one with "broad spectrum" distribution of reactivity from a late bleeding (aK), and to "luminal epithelial antigen" (aLEA) were applied to formalin fixed paraffin embedded sections of human normal and neoplastic mammary and salivary glands using an indirect immunoperoxidase method. aK1 reacted with myoepithelial cells, aLEA with luminal epithelial cells and aK with both cell types in normal mammary and salivary gland. In breast carcinomas the majority of intraluminal and infiltrating carcinoma cells reacted with aLEA but not with aK1 which reacted only with surrounding myoepithelial cells. aK reacted with both myoepithelial cells and with intraluminal and infiltrating tumour cells. In the salivary gland adenomas the majority of cells reacted with aK, and those cells arranged in a tubular fashion reacted with aLEA.

Luminal DMSO: Effects on Detrusor and Urothelial/Lamina Propria Function

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Katrina J. Smith

2014-01-01

Full Text Available DMSO is used as a treatment for interstitial cystitis and this study examined the effects of luminal DMSO treatment on bladder function and histology. Porcine bladder was incubated without (controls or with DMSO (50% applied to the luminal surface and the release of ATP, acetylcholine, and LDH assessed during incubation and in tissues strips after DMSO incubation. Luminally applied DMSO caused ATP, Ach, and LDH release from the urothelial surface during treatment, with loss of urothelial layers also evident histologically. In strips of urothelium/lamina propria from DMSO pretreated bladders the release of both ATP and Ach was depressed, while contractile responses to carbachol were enhanced. Detrusor muscle contractile responses to carbachol were not affected by DMSO pretreatment, but neurogenic responses to electrical field stimulation were enhanced. The presence of an intact urothelium/lamina propria inhibited detrusor contraction to carbachol by 53% and this inhibition was significantly reduced in DMSO pretreated tissues. Detection of LDH in the treatment medium suggests that DMSO permeabilised urothelial membranes causing leakage of cytosolic contents including ATP and Ach rather than enhancing release of these mediators. The increase in contractile response and high levels of ATP are consistent with initial flare up in IC/PBS symptoms after DMSO treatment.

Evolution of massive stars in very young clusters and associations

International Nuclear Information System (INIS)

Stothers, R.B.

1985-01-01

The stellar content of very young galactic clusters and associations with well-determined ages has been analyzed statistically to derive information about stellar evolution at high masses. The adopted approach is semiempirical and uses natural spectroscopic groups of stars on the H-R diagram, together with the stars' apparent magnitudes. Cluster distance moduli are not used. Only the most basic elements of stellar evolution theory are required as input. For stellar aggregates with main-sequence turnups at spectral types between O9 and B2, the following conclusions have emerged: (1) O-type main-sequence stars evolve to a spectral type of B1 during core hydrogen burning; (2) most of the O-type blue stragglers are newly formed massive stars, burning core hydrogen; (3) supergiants lying redward of the turnup, as well as most, or all, of the Wolf-Rayet stars, are burning core helium; (4) Wolf-Rayet stars originally had masses greater than 30--40 M/sub sun/, while known M-type supergiants evolved from star less massive than approx.30 M/sub sun/; (5) phases of evolution following core helium burning are unobservably rapid, presumably on account of copious neutrino emission; and (6) formation of stars of high mass continues vigorously in most young clusters and association for approx.8 x 10 6 yr. The important result concerning the evolutionary status of the supergiants depends only on the total number of these stars and not on how they are distributed between blue and red types; the result, however, may be sensitive to the assumed amount of convective core overshooting. Conclusions in the present work refer chiefly to luminous stars in the mass range 10--40 M/sub sun/, belonging to aggregates in the age range (6--25) x 10 6 yr

Very Rapid High-amplitude Gamma-Ray Variability in Luminous Blazar PKS 1510-089 Studied with Fermi-LAT

Energy Technology Data Exchange (ETDEWEB)

Saito, S.; Stawarz, L.; Tanaka, Y.T.; Takahashi, T.; Madejski, G.; D' Ammando, F.

2013-03-20

Here we report on the detailed analysis of the γ-ray light curve of a luminous blazar PKS 1510-089 observed in the GeV range with the Large Area Telescope (LAT) onboard the Fermi satellite during the period 2011 September - December. By investigating the properties of the detected three major flares with the shortest possible time binning allowed by the photon statistics, we find a variety of temporal characteristics and variability patterns. This includes a clearly asymmetric profile (with a faster flux rise and a slower decay) of the flare resolved on sub-daily timescales, a superposition of many short uncorrelated flaring events forming the apparently coherent longer-duration outburst, and a huge single isolated outburst unresolved down to the timescale of three-hours. In the latter case we estimate the corresponding γ-ray flux doubling timescale to be below one hour, which is extreme and never previously reported for any active galaxy

Whole-genome analyses resolve early branches in the tree of life of modern birds

DEFF Research Database (Denmark)

Sicheritz-Pontén, Thomas; Li, Cai; Li, Bo

2014-01-01

To better determine the history of modern birds, we performed a genome-scale phylogenetic analysis of 48 species representing all orders of Neoaves using phylogenomic methods created to handle genome-scale data. We recovered a highly resolved tree that confirms previously controversial sister...... or close relationships. We identified the first divergence in Neoaves, two groups we named Passerea and Columbea, representing independent lineages of diverse and convergently evolved land and water bird species. Among Passerea, we infer the common ancestor of core landbirds to have been an apex predator...... and confirm independent gains of vocal learning. Among Columbea, we identify pigeons and flamingoes as belonging to sister clades. Even with whole genomes, some of the earliest branches in Neoaves proved challenging to resolve, which was best explained by massive protein-coding sequence convergence and high...

Massive Conformal Gravity

International Nuclear Information System (INIS)

Faria, F. F.

2014-01-01

We construct a massive theory of gravity that is invariant under conformal transformations. The massive action of the theory depends on the metric tensor and a scalar field, which are considered the only field variables. We find the vacuum field equations of the theory and analyze its weak-field approximation and Newtonian limit.

The effects of luminance contrast, colour combinations, font, and search time on brand icon legibility.

Science.gov (United States)

Ko, Ya-Hsien

2017-11-01

This study explored and identified the effects of luminance contrast, colour combinations, font, and search time on brand icon legibility. A total of 108 participants took part in the experiment. As designed, legibility was measured as a function of the following independent variables: four levels of luminance contrast, sixteen target/background colour combinations, two fonts, and three search times. The results showed that a luminance contrast of 18:1 provided readers with the best legibility. Yellow on black, yellow on blue, and white on blue were the three most legible colour combinations. One of this study's unique findings was that colour combinations may play an even more important role than luminance contrast in the overall legibility of brand icon design. The 12-s search time corresponded with the highest legibility. Arial font was more legible than Times New Roman. These results provide some guidance for brand icon and product advertisement design. Copyright © 2017 Elsevier Ltd. All rights reserved.

SURVEY OF THE ENTOMOFAUNA THROUGH LUMINOUS TRAP

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V. R. Andrade Neto

2014-09-01

Full Text Available The demand for forest-based raw materials for energy, construction, paper pulp and the pressure to comply with legal requirements concerning environmental legislation, for example, the replacement of the permanent preservation area, legal reserve and recovery of degraded area, leads to encourage the production of healthy seedlings in a health status to do not compromise their future production. The present study aimed to survey the entomofauna population using the “Luiz de Queiroz” model of luminous trap, with white and red fluorescent lamps. The experiment was conducted at the nursery “Flora Sinop” in Sinop – MT. The survey was conducted weekly between the months of April to July 2010, totaling 4 months sand, 32 samples collected. The orders Hemiptera and Coleoptera showed the highest number of individuals captured, either in attraction with white or red light. It was captured 10.089 individuals, 9.339 collected under the influence of white light, representing 92,56%, and 750 with red light, only 7,44% of the total. The white light luminous trap possessed greater efficiency in the attraction of insects when compared with the red light trap.

Massive stars dying alone: Extremely remote environments of SN2009ip and SN2010jp

Science.gov (United States)

Smith, Nathan

2014-10-01

We propose an imaging study of the astonishingly remote environments of two recent supernovae (SNe): SN2009ip and SN2010jp. Both were unusual Type IIn explosions that crashed into dense circumstellar material (CSM) ejected by the star shortly before explosion. The favored progenitors of these SNe are very massive luminous blue variable (LBV) stars. In fact, SN2009ip presents an extraordinay case where the LBV-like progenitor was actually detected directly in archival HST data, and where we obtained spectra and photometry for numerous pre-SN eruptions. No other SN has this treasure trove of detailed information about the progenitor (not even SN1987A). SN2010jp represents a possible collapsar-powered event, since it showed evidence of a fast bipolar jet in spectra and a low 56Ni mass; this would be an analog of the black-hole forming explosions that cause gamma ray bursts, but where the relativistic jet is damped by a residual H envelope on the star. In both cases, the only viable models for these SNe involve extremely massive (initial masses of 40-100 Msun) progenitor stars. This seems at odds with their extremely remote environments in the far outskirts of their host galaxies, with no detected evidence for an underlying massive star population in ground-based data (nor in the single shallow WFPC2/F606W image of SN2009ip). Here we propose deep UV HST images to search for any mid/late O-type stars nearby, deep red images to detect any red supergiants, and an H-alpha image to search for any evidence of ongoing star formation in the vicinity. These observations will place important and demanding constraints on the initial masses and ages of these progenitors.

Different responses of spontaneous and stimulus-related alpha activity to ambient luminance changes.

Science.gov (United States)

Benedetto, Alessandro; Lozano-Soldevilla, Diego; VanRullen, Rufin

2017-12-04

Alpha oscillations are particularly important in determining our percepts and have been implicated in fundamental brain functions. Oscillatory activity can be spontaneous or stimulus-related. Furthermore, stimulus-related responses can be phase- or non-phase-locked to the stimulus. Non-phase-locked (induced) activity can be identified as the average amplitude changes in response to a stimulation, while phase-locked activity can be measured via reverse-correlation techniques (echo function). However, the mechanisms and the functional roles of these oscillations are far from clear. Here, we investigated the effect of ambient luminance changes, known to dramatically modulate neural oscillations, on spontaneous and stimulus-related alpha. We investigated the effect of ambient luminance on EEG alpha during spontaneous human brain activity at rest (experiment 1) and during visual stimulation (experiment 2). Results show that spontaneous alpha amplitude increased by decreasing ambient luminance, while alpha frequency remained unaffected. In the second experiment, we found that under low-luminance viewing, the stimulus-related alpha amplitude was lower, and its frequency was slightly faster. These effects were evident in the phase-locked part of the alpha response (echo function), but weaker or absent in the induced (non-phase-locked) alpha responses. Finally, we explored the possible behavioural correlates of these modulations in a monocular critical flicker frequency task (experiment 3), finding that dark adaptation in the left eye decreased the temporal threshold of the right eye. Overall, we found that ambient luminance changes impact differently on spontaneous and stimulus-related alpha expression. We suggest that stimulus-related alpha activity is crucial in determining human temporal segmentation abilities. © 2017 Federation of European Neuroscience Societies and John Wiley & Sons Ltd.

High luminous flux from single crystal phosphor-converted laser-based white lighting system

KAUST Repository

Cantore, Michael

2015-12-14

The efficiency droop of light emitting diodes (LEDs) with increasing current density limits the amount of light emitted per wafer area. Since low current densities are required for high efficiency operation, many LED die are needed for high power white light illumination systems. In contrast, the carrier density of laser diodes (LDs) clamps at threshold, so the efficiency of LDs does not droop above threshold and high efficiencies can be achieved at very high current densities. The use of a high power blue GaN-based LD coupled with a single crystal Ce-doped yttrium aluminum garnet (YAG:Ce) sample was investigated for white light illumination applications. Under CW operation, a single phosphor-converted LD (pc-LD) die produced a peak luminous efficacy of 86.7 lm/W at 1.4 A and 4.24 V and a peak luminous flux of 1100 lm at 3.0 A and 4.85 V with a luminous efficacy of 75.6 lm/W. Simulations of a pc-LD confirm that the single crystal YAG:Ce sample did not experience thermal quenching at peak LD operating efficiency. These results show that a single pc-LD die is capable of emitting enough luminous flux for use in a high power white light illumination system.

Massive Black Hole Binary Evolution

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Merritt David

2005-11-01

Full Text Available Coalescence of binary supermassive black holes (SBHs would constitute the strongest sources of gravitational waves to be observed by LISA. While the formation of binary SBHs during galaxy mergers is almost inevitable, coalescence requires that the separation between binary components first drop by a few orders of magnitude, due presumably to interaction of the binary with stars and gas in a galactic nucleus. This article reviews the observational evidence for binary SBHs and discusses how they would evolve. No completely convincing case of a bound, binary SBH has yet been found, although a handful of systems (e.g. interacting galaxies; remnants of galaxy mergers are now believed to contain two SBHs at projected separations of <~ 1kpc. N-body studies of binary evolution in gas-free galaxies have reached large enough particle numbers to reproduce the slow, “diffusive” refilling of the binary’s loss cone that is believed to characterize binary evolution in real galactic nuclei. While some of the results of these simulations - e.g. the binary hardening rate and eccentricity evolution - are strongly N-dependent, others - e.g. the “damage” inflicted by the binary on the nucleus - are not. Luminous early-type galaxies often exhibit depleted cores with masses of ~ 1-2 times the mass of their nuclear SBHs, consistent with the predictions of the binary model. Studies of the interaction of massive binaries with gas are still in their infancy, although much progress is expected in the near future. Binary coalescence has a large influence on the spins of SBHs, even for mass ratios as extreme as 10:1, and evidence of spin-flips may have been observed.

Massive gravity from bimetric gravity

International Nuclear Information System (INIS)

Baccetti, Valentina; Martín-Moruno, Prado; Visser, Matt

2013-01-01

We discuss the subtle relationship between massive gravity and bimetric gravity, focusing particularly on the manner in which massive gravity may be viewed as a suitable limit of bimetric gravity. The limiting procedure is more delicate than currently appreciated. Specifically, this limiting procedure should not unnecessarily constrain the background metric, which must be externally specified by the theory of massive gravity itself. The fact that in bimetric theories one always has two sets of metric equations of motion continues to have an effect even in the massive gravity limit, leading to additional constraints besides the one set of equations of motion naively expected. Thus, since solutions of bimetric gravity in the limit of vanishing kinetic term are also solutions of massive gravity, but the contrary statement is not necessarily true, there is no complete continuity in the parameter space of the theory. In particular, we study the massive cosmological solutions which are continuous in the parameter space, showing that many interesting cosmologies belong to this class. (paper)

EVIDENCE FOR WIDESPREAD ACTIVE GALACTIC NUCLEUS ACTIVITY AMONG MASSIVE QUIESCENT GALAXIES AT z ∼ 2

International Nuclear Information System (INIS)

Olsen, Karen P.; Rasmussen, Jesper; Toft, Sune; Zirm, Andrew W.

2013-01-01

We quantify the presence of active galactic nuclei (AGNs) in a mass-complete (M * > 5 × 10 10 M ☉ ) sample of 123 star-forming and quiescent galaxies at 1.5 ≤ z ≤ 2.5, using X-ray data from the 4 Ms Chandra Deep Field-South (CDF-S) survey. 41% ± 7% of the galaxies are detected directly in X-rays, 22% ± 5% with rest-frame 0.5-8 keV luminosities consistent with hosting luminous AGNs (L 0.5-8keV > 3 × 10 42 erg s –1 ). The latter fraction is similar for star-forming and quiescent galaxies, and does not depend on galaxy stellar mass, suggesting that perhaps luminous AGNs are triggered by external effects such as mergers. We detect significant mean X-ray signals in stacked images for both the individually non-detected star-forming and quiescent galaxies, with spectra consistent with star formation only and/or a low-luminosity AGN in both cases. Comparing star formation rates inferred from the 2-10 keV luminosities to those from rest-frame IR+UV emission, we find evidence for an X-ray excess indicative of low-luminosity AGNs. Among the quiescent galaxies, the excess suggests that as many as 70%-100% of these contain low- or high-luminosity AGNs, while the corresponding fraction is lower among star-forming galaxies (43%-65%). Our discovery of the ubiquity of AGNs in massive, quiescent z ∼ 2 galaxies provides observational support for the importance of AGNs in impeding star formation during galaxy evolution.

The Research Search For The Least Beneficial Overcast Sky And Progress In Defining Its Luminance Gradation Function

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Kittler R.

2014-09-01

Full Text Available Recently illuminance levels under ISO/CIE homogeneous standard sky types were characterised in their relative terms after ISO/CIE (2004, 2003 standardised as normalised by the luminance in the zenith. Sky luminance and horizontal illuminance based on the gradation and scattering indicatrix functions, including the extreme overcast cases frequently encountered in nature, were recently determined in absolute physical units of luminance in kilocandles per meter square and of illuminance in kilolux. The historical search to find energy and visibility critical sky luminance distributions shows a progression of steps in studying the worst or critical overcast situations. That progression has enabled the determination and evaluation of interior illuminance for comparison of the merits of dual daylighting and artificial lighting under established criteria for comfortable visibility.

Stellar Feedback in Massive Star-Forming Regions

Science.gov (United States)

Baldwin, Jack; Pellegrini, Eric; Ferland, Gary; Murray, Norm; Hanson, Margaret

2008-02-01

Star formation rates and chemical evolution are controlled in part by the interaction of stellar radiation and winds with the remnant molecular gas from which the stars have formed. We are carrying out a detailed, panchromatic study in the two nearest giant star-forming regions to nail down the physics that produces the 10-20 parsec bubbles seen to surround young massive clusters in the Milky Way. This will determine if and how the clusters disrupt their natal giant molecular clouds (GMCs). Here we request 4 nights on the Blanco telescope to obtain dense grids of optical long-slit spectra criss-crossing each nebula. These will cover the [S II] doublet (to measure N_e) and also [O III], H(beta), [O I], H(alpha) and [N II] to measure the ionization mechanism and ionization parameter, at ~3000 different spots in each nebula. From this we can determine a number of dynamically important quantities, such as the gas density and temperature, hence pressure in and around these bubbles. These quantities can be compared to the dynamical (gravitationally induced) pressure, and the radiation pressure. All can be employed in dynamical models for the evolution of a GMC under the influence of an embedded massive star cluster. This research will elucidate the detailed workings of the star-forming regions which dominate the star formation rate in the Milky Way, and also will steadily improve our calibration and understanding of more distant, less well-resolved objects such as ULIRGS, Lyman break, and submillimeter galaxies.

Vocal Fold Epithelial Response to Luminal Osmotic Perturbation

Science.gov (United States)

Sivasankar, Mahalakshmi; Fisher, Kimberly V.

2007-01-01

Purpose: Dry-air challenges increase the osmolarity of fluid lining the luminal surface of the proximal airway. The homeostasis of surface fluid is thought to be essential for voice production and laryngeal defense. Therefore, the authors hypothesized that viable vocal fold epithelium would generate a water flux to reduce an osmotic challenge (150…

Vaidya spacetime in massive gravity's rainbow

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Yaghoub Heydarzade

2017-11-01

Full Text Available In this paper, we will analyze the energy dependent deformation of massive gravity using the formalism of massive gravity's rainbow. So, we will use the Vainshtein mechanism and the dRGT mechanism for the energy dependent massive gravity, and thus analyze a ghost free theory of massive gravity's rainbow. We study the energy dependence of a time-dependent geometry, by analyzing the radiating Vaidya solution in this theory of massive gravity's rainbow. The energy dependent deformation of this Vaidya metric will be performed using suitable rainbow functions.

The luminous and the grey

CERN Document Server

Batchelor, David

2014-01-01

Color surrounds us: the lush green hues of trees and grasses, the variant blues of water and the sky, the bright pops of yellow and red from flowers. But at the same time, color lies at the limits of language and understanding. In this absorbing sequel to Chromophobia-which addresses the extremes of love and loathing provoked by color since antiquity-David Batchelor charts color's more ambiguous terrain.   The Luminous and the Grey explores the places where color comes into being and where it fades away, probing when it begins and when it ends both in the imagination and in the material world.

MassiveNuS: cosmological massive neutrino simulations

Science.gov (United States)

Liu, Jia; Bird, Simeon; Zorrilla Matilla, José Manuel; Hill, J. Colin; Haiman, Zoltán; Madhavacheril, Mathew S.; Petri, Andrea; Spergel, David N.

2018-03-01

The non-zero mass of neutrinos suppresses the growth of cosmic structure on small scales. Since the level of suppression depends on the sum of the masses of the three active neutrino species, the evolution of large-scale structure is a promising tool to constrain the total mass of neutrinos and possibly shed light on the mass hierarchy. In this work, we investigate these effects via a large suite of N-body simulations that include massive neutrinos using an analytic linear-response approximation: the Cosmological Massive Neutrino Simulations (MassiveNuS). The simulations include the effects of radiation on the background expansion, as well as the clustering of neutrinos in response to the nonlinear dark matter evolution. We allow three cosmological parameters to vary: the neutrino mass sum Mν in the range of 0–0.6 eV, the total matter density Ωm, and the primordial power spectrum amplitude As. The rms density fluctuation in spheres of 8 comoving Mpc/h (σ8) is a derived parameter as a result. Our data products include N-body snapshots, halo catalogues, merger trees, ray-traced galaxy lensing convergence maps for four source redshift planes between zs=1–2.5, and ray-traced cosmic microwave background lensing convergence maps. We describe the simulation procedures and code validation in this paper. The data are publicly available at http://columbialensing.org.

Radioisotope treatment for benign strictures of non-vascular luminal organs

International Nuclear Information System (INIS)

Shin, Ji Hoon

2006-01-01

Tissue hyperplasia in one of the most frequently encountered complications when self-expanding stents are placed in benign non-vascular luminal organ strictures, thus causing of the lumen. The investigators postulated that ionizing irradiation could be applied to prevent restenosis caused by tissue hyperplasia in non-vascular luminal organs as it reduced coronary or peripheral arterial narrowing successfully. The authors combined β-irradiation using 188 Re-MAG 3 solution with balloon for animal and clinical studies because this new treatment approach had the advantages such as low penetration depth of β-ray, self-centering irradiation, and mechanical effect of balloon dilation over using γ-irradiation with afterloading devices. In this article, the concept and mechanism of radioisotope balloon dilation, and animal and clinical studies using radioisotope balloon dilation are reviewed

Holographically viable extensions of topologically massive and minimal massive gravity?

Science.gov (United States)

Altas, Emel; Tekin, Bayram

2016-01-01

Recently [E. Bergshoeff et al., Classical Quantum Gravity 31, 145008 (2014)], an extension of the topologically massive gravity (TMG) in 2 +1 dimensions, dubbed as minimal massive gravity (MMG), which is free of the bulk-boundary unitarity clash that inflicts the former theory and all the other known three-dimensional theories, was found. Field equations of MMG differ from those of TMG at quadratic terms in the curvature that do not come from the variation of an action depending on the metric alone. Here we show that MMG is a unique theory and there does not exist a deformation of TMG or MMG at the cubic and quartic order (and beyond) in the curvature that is consistent at the level of the field equations. The only extension of TMG with the desired bulk and boundary properties having a single massive degree of freedom is MMG.

DACH1: its role as a classifier of long term good prognosis in luminal breast cancer.

Directory of Open Access Journals (Sweden)

Desmond G Powe

Full Text Available BACKGROUND: Oestrogen receptor (ER positive (luminal tumours account for the largest proportion of females with breast cancer. Theirs is a heterogeneous disease presenting clinical challenges in managing their treatment. Three main biological luminal groups have been identified but clinically these can be distilled into two prognostic groups in which Luminal A are accorded good prognosis and Luminal B correlate with poor prognosis. Further biomarkers are needed to attain classification consensus. Machine learning approaches like Artificial Neural Networks (ANNs have been used for classification and identification of biomarkers in breast cancer using high throughput data. In this study, we have used an artificial neural network (ANN approach to identify DACH1 as a candidate luminal marker and its role in predicting clinical outcome in breast cancer is assessed. MATERIALS AND METHODS: A reiterative ANN approach incorporating a network inferencing algorithm was used to identify ER-associated biomarkers in a publically available cDNA microarray dataset. DACH1 was identified in having a strong influence on ER associated markers and a positive association with ER. Its clinical relevance in predicting breast cancer specific survival was investigated by statistically assessing protein expression levels after immunohistochemistry in a series of unselected breast cancers, formatted as a tissue microarray. RESULTS: Strong nuclear DACH1 staining is more prevalent in tubular and lobular breast cancer. Its expression correlated with ER-alpha positive tumours expressing PgR, epithelial cytokeratins (CK18/19 and 'luminal-like' markers of good prognosis including FOXA1 and RERG (p<0.05. DACH1 is increased in patients showing longer cancer specific survival and disease free interval and reduced metastasis formation (p<0.001. Nuclear DACH1 showed a negative association with markers of aggressive growth and poor prognosis. CONCLUSION: Nuclear DACH1 expression

Glossiness and perishable food quality: visual freshness judgment of fish eyes based on luminance distribution.

Science.gov (United States)

Murakoshi, Takuma; Masuda, Tomohiro; Utsumi, Ken; Tsubota, Kazuo; Wada, Yuji

2013-01-01

Previous studies have reported the effects of statistics of luminance distribution on visual freshness perception using pictures which included the degradation process of food samples. However, these studies did not examine the effect of individual differences between the same kinds of food. Here we elucidate whether luminance distribution would continue to have a significant effect on visual freshness perception even if visual stimuli included individual differences in addition to the degradation process of foods. We took pictures of the degradation of three fishes over 3.29 hours in a controlled environment, then cropped square patches of their eyes from the original images as visual stimuli. Eleven participants performed paired comparison tests judging the visual freshness of the fish eyes at three points of degradation. Perceived freshness scores (PFS) were calculated using the Bradley-Terry Model for each image. The ANOVA revealed that the PFS for each fish decreased as the degradation time increased; however, the differences in the PFS between individual fish was larger for the shorter degradation time, and smaller for the longer degradation time. A multiple linear regression analysis was conducted in order to determine the relative importance of the statistics of luminance distribution of the stimulus images in predicting PFS. The results show that standard deviation and skewness in luminance distribution have a significant influence on PFS. These results show that even if foodstuffs contain individual differences, visual freshness perception and changes in luminance distribution correlate with degradation time.

Classification of radioactive self-luminous light sources - approved 1975. NBS Handbook 116

International Nuclear Information System (INIS)

Anon.

1977-01-01

The standard establishes the classification of certain radioactive self-luminous light sources according to radionuclide, type of source, activity, and performance requirements. The objectives are to establish minimum prototype testing requirements for radioactive self-luminous light sources, to promote uniformity of marking such sources, and to establish minimum physical performance for such sources. The standard is primarily directed toward assuring adequate containment of the radioactive material. Testing procedures and classification designations are specified for discoloration, temperature, thermal shock, reduced pressure, impact, vibration, and immersion. A range of test requirements is presented according to intended usage and source activity

Visual sensitivity for luminance and chromatic stimuli during the execution of smooth pursuit and saccadic eye movements.

Science.gov (United States)

Braun, Doris I; Schütz, Alexander C; Gegenfurtner, Karl R

2017-07-01

Visual sensitivity is dynamically modulated by eye movements. During saccadic eye movements, sensitivity is reduced selectively for low-spatial frequency luminance stimuli and largely unaffected for high-spatial frequency luminance and chromatic stimuli (Nature 371 (1994), 511-513). During smooth pursuit eye movements, sensitivity for low-spatial frequency luminance stimuli is moderately reduced while sensitivity for chromatic and high-spatial frequency luminance stimuli is even increased (Nature Neuroscience, 11 (2008), 1211-1216). Since these effects are at least partly of different polarity, we investigated the combined effects of saccades and smooth pursuit on visual sensitivity. For the time course of chromatic sensitivity, we found that detection rates increased slightly around pursuit onset. During saccades to static and moving targets, detection rates dropped briefly before the saccade and reached a minimum at saccade onset. This reduction of chromatic sensitivity was present whenever a saccade was executed and it was not modified by subsequent pursuit. We also measured contrast sensitivity for flashed high- and low-spatial frequency luminance and chromatic stimuli during saccades and pursuit. During saccades, the reduction of contrast sensitivity was strongest for low-spatial frequency luminance stimuli (about 90%). However, a significant reduction was also present for chromatic stimuli (about 58%). Chromatic sensitivity was increased during smooth pursuit (about 12%). These results suggest that the modulation of visual sensitivity during saccades and smooth pursuit is more complex than previously assumed. Copyright © 2017 Elsevier Ltd. All rights reserved.

The Highly Luminous Type Ibn Supernova ASASSN-14ms

DEFF Research Database (Denmark)

Vallely, P. J.; Prieto, J. L.; Stanek, K. Z.

2018-01-01

We present photometric and spectroscopic follow-up observations of the highly luminous Type Ibn supernova ASASSN-14ms, which was discovered on UT 2014-12-26.61 at $m_V \\sim 16.5$. With a peak absolute $V$-band magnitude brighter than $-20.5$, a peak bolometric luminosity of $1.7 \\times 10......^{44}$ ergs s$^{-1}$, and a total radiated energy of $2.1 \\times 10^{50}$ ergs, ASASSN-14ms is one of the most luminous Type Ibn supernovae yet discovered. In simple models, the most likely power source for this event is a combination of the radioactive decay of $^{56}$Ni and $^{56}$Co at late times...... and the interaction of supernova ejecta with the progenitor's circumstellar medium at early times, although we cannot rule out the possibility of a magnetar-powered light curve. The presence of a dense circumstellar medium is indicated by the intermediate-width He I features in the spectra. The faint ($m_g \\sim 21...

A CANDIDATE FOR THE MOST LUMINOUS OB ASSOCIATION IN THE GALAXY

International Nuclear Information System (INIS)

Rahman, Mubdi; Matzner, Christopher; Moon, Dae-Sik

2011-01-01

The Milky Way harbors giant H II regions, which may be powered by star complexes more luminous than any known Galactic OB association. Being across the disk of the Galaxy, however, these brightest associations are severely extinguished and confused. We present a search for one such association toward the most luminous H II region in the recent catalog by Murray and Rahman, which, at ∼9.7 kpc, has a recombination rate of ∼7 x 10 51 s -1 . Prior searches have identified only small-scale clustering around the rim of this shell-like region, but the primary association has not previously been identified. We apply a near-infrared color selection and find an overdensity of point sources toward its southern central part. The colors and magnitudes of these excess sources are consistent with O- and early B-type stars at extinctions 0.96 K < 1.2, and they are sufficiently numerous (406 ± 102 after subtraction of field sources) to ionize the surrounding H II region, making this a candidate for the most luminous OB association in the Galaxy. We reject an alternate theory, in which the apparent excess is caused by localized extinction, as inconsistent with source demographics.

Os efeitos da idade na percepção visual de grades senoidais em luminância baixa The effects of age on visual perception of sine-wave gratings at low luminance

Directory of Open Access Journals (Sweden)

Natanael Antonio dos Santos

2006-01-01

Full Text Available O objetivo deste trabalho foi investigar a função de sensibilidade ao contraste (FSC de adultos e idosos (20-23, 30-39, 40-49, 50-59, 60-69 anos para grades senoidais de 0,25 a 2 cpg em luminância baixa. Todos os participantes apresentavam acuidade visual normal e se encontravam livres de doenças oculares identificáveis. Foram estimados limiares de contraste para 30 participantes (seis em cada faixa etária utilizando o método psicofísico da escolha forçada. Neste método, os participantes tinham que escolher um estímulo contendo uma freqüência de teste (grade senoidal em baixo contraste ou um estímulo neutro com luminância média de 0,7 cd/m². Os resultados mostraram que os grupos de 50-59 e 60-69 anos apresentaram prejuízos significativos na FSC nas freqüências espaciais de 1 e 2 cpg comparados ao grupo de 20-23 anos. Estes resultados sugerem alterações relacionadas à idade na FSC de freqüências espaciais em níveis baixos de luminância.The aim of this work was to investigate the contrast sensitivity function for sine-wave gratings in the range between 0.25-2 cpd in young and older adults (20-23, 30-39, 40-49, 50-59, 60-69 years old using low luminance. All subjects were free from identifiable ocular disease and had normal acuity. We measured the contrast thresholds for 30 participants (six volunteers in each age using the psychophysical forced-choice staircase method. In this method the volunteers had to choose the stimulus containing a test frequency at low contrast (e.g., a sine-wave grating, or another neutral stimulus at mean luminance (0.7 cd/m². The results showed significant changes of CSF for sine-wave gratings at 1 and 2 cpd for the adults 50-59 and 60-69 years old compared to the adults of 20-23 years old. These results suggest age-related changes in the CSF for sine-wave grating at low luminance levels.

Transferable chloramphenicol resistance determinant in luminous Vibrio harveyi from penaeid shrimp Penaeus monodon larvae

Directory of Open Access Journals (Sweden)

Thangapalam Jawahar Abraham

2016-12-01

Full Text Available Antibiotic-resistant luminous Vibrio harveyi strains isolated from Penaeus monodon larvae were screened for the possession of transferable resistance determinants. All the strains were resistant to chloramphenicol and the determinant coding for chloramphenicol resistance was transferred to Escherichia coli at frequencies of 9.50x10-4 to 4.20x10-4. The results probably suggest the excessive use of chloramphenicol in shrimp hatcheries to combat luminous vibriosis.

10 CFR 32.101 - Schedule B-prototype tests for luminous safety devices for use in aircraft.

Science.gov (United States)

2010-01-01

....101 Schedule B—prototype tests for luminous safety devices for use in aircraft. An applicant for a... 10 Energy 1 2010-01-01 2010-01-01 false Schedule B-prototype tests for luminous safety devices for use in aircraft. 32.101 Section 32.101 Energy NUCLEAR REGULATORY COMMISSION SPECIFIC DOMESTIC LICENSES...

The Atacama Cosmology Telescope: ACT-CL J0102-4915 'EL GORDO', A Massive Merging Cluster at Redshift 0.87

Science.gov (United States)

Menanteau, Felipe; Hughes, John P.; Sifon, Cristobal; Hilton, Matt; Gonzalez, Jorge; Infante, Leopoldo; Barrientos, L. Felipe; Baker, Andrew J.; Bond, John R.; Das, Sudeep;

SN 2010U: A LUMINOUS NOVA IN NGC 4214

International Nuclear Information System (INIS)

Humphreys, Roberta M.; Helton, L. Andrew; Prieto, Jose L.; Rosenfield, Philip; Williams, Benjamin; Murphy, Jeremiah; Dalcanton, Julianne; Gilbert, Karoline; Kochanek, Christopher S.; Stanek, K. Z.; Khan, Rubab; Szczygiel, Dorota; Mogren, Karen; Fesen, Robert A.; Milisavljevic, Dan

2010-01-01

The luminosity, light curve, post-maximum spectrum, and lack of a progenitor on deep pre-outburst images suggest that SN 2010U was a luminous, fast nova. Its outburst magnitude is consistent with that for a fast nova using the maximum magnitude-rate of decline relationship for classical novae.

Massive Supergravity and Deconstruction

CERN Document Server

Gregoire, T; Shadmi, Y; Gregoire, Thomas; Schwartz, Matthew D; Shadmi, Yael

2004-01-01

We present a simple superfield Lagrangian for massive supergravity. It comprises the minimal supergravity Lagrangian with interactions as well as mass terms for the metric superfield and the chiral compensator. This is the natural generalization of the Fierz-Pauli Lagrangian for massive gravity which comprises mass terms for the metric and its trace. We show that the on-shell bosonic and fermionic fields are degenerate and have the appropriate spins: 2, 3/2, 3/2 and 1. We then study this interacting Lagrangian using goldstone superfields. We find that a chiral multiplet of goldstones gets a kinetic term through mixing, just as the scalar goldstone does in the non-supersymmetric case. This produces Planck scale (Mpl) interactions with matter and all the discontinuities and unitarity bounds associated with massive gravity. In particular, the scale of strong coupling is (Mpl m^4)^1/5, where m is the multiplet's mass. Next, we consider applications of massive supergravity to deconstruction. We estimate various qu...

COLA with massive neutrinos

Energy Technology Data Exchange (ETDEWEB)

Wright, Bill S.; Winther, Hans A.; Koyama, Kazuya, E-mail: bill.wright@port.ac.uk, E-mail: hans.winther@port.ac.uk, E-mail: kazuya.koyama@port.ac.uk [Institute of Cosmology and Gravitation, University of Portsmouth, Dennis Sciama Building, Burnaby Road, Portsmouth, Hampshire, PO1 3FX (United Kingdom)

2017-10-01

The effect of massive neutrinos on the growth of cold dark matter perturbations acts as a scale-dependent Newton's constant and leads to scale-dependent growth factors just as we often find in models of gravity beyond General Relativity. We show how to compute growth factors for ΛCDM and general modified gravity cosmologies combined with massive neutrinos in Lagrangian perturbation theory for use in COLA and extensions thereof. We implement this together with the grid-based massive neutrino method of Brandbyge and Hannestad in MG-PICOLA and compare COLA simulations to full N -body simulations of ΛCDM and f ( R ) gravity with massive neutrinos. Our implementation is computationally cheap if the underlying cosmology already has scale-dependent growth factors and it is shown to be able to produce results that match N -body to percent level accuracy for both the total and CDM matter power-spectra up to k ∼< 1 h /Mpc.

Measurement of luminance noise and chromaticity noise of LCDs with a colorimeter and a color camera

Science.gov (United States)

Roehrig, H.; Dallas, W. J.; Krupinski, E. A.; Redford, Gary R.

2007-09-01

This communication focuses on physical evaluation of image quality of displays for applications in medical imaging. In particular we were interested in luminance noise as well as chromaticity noise of LCDs. Luminance noise has been encountered in the study of monochrome LCDs for some time, but chromaticity noise is a new type of noise which has been encountered first when monochrome and color LCDs were compared in an ROC study. In this present study one color and one monochrome 3 M-pixel LCDs were studied. Both were DICOM calibrated with equal dynamic range. We used a Konica Minolta Chroma Meter CS-200 as well as a Foveon color camera to estimate luminance and chrominance variations of the displays. We also used a simulation experiment to estimate luminance noise. The measurements with the colorimeter were consistent. The measurements with the Foveon color camera were very preliminary as color cameras had never been used for image quality measurements. However they were extremely promising. The measurements with the colorimeter and the simulation results showed that the luminance and chromaticity noise of the color LCD were larger than that of the monochrome LCD. Under the condition that an adequate calibration method and image QA/QC program for color displays are available, we expect color LCDs may be ready for radiology in very near future.

Minimal massive 3D gravity

International Nuclear Information System (INIS)

Bergshoeff, Eric; Merbis, Wout; Hohm, Olaf; Routh, Alasdair J; Townsend, Paul K

2014-01-01

We present an alternative to topologically massive gravity (TMG) with the same ‘minimal’ bulk properties; i.e. a single local degree of freedom that is realized as a massive graviton in linearization about an anti-de Sitter (AdS) vacuum. However, in contrast to TMG, the new ‘minimal massive gravity’ has both a positive energy graviton and positive central charges for the asymptotic AdS-boundary conformal algebra. (paper)

Informational primacy of visual dimensions: specialized roles for luminance and chromaticity in figure-ground perception.

Science.gov (United States)

Yamagishi, N; Melara, R D

2001-07-01

Three experiments were conducted to examine the distinct contributions of two visual dimensions to figure-ground segregation. In each experiment, pattern identification was assessed by asking observers to judge whether a near-threshold test pattern was the same or different in shape to a high-contrast comparison pattern. A test pattern could differ from its background along one dimension, either luminance (luminance tasks) or chromaticity (chromaticity tasks). In each task, performance in a baseline condition, in which the test pattern was intact, was compared with performance in each of several degradation conditions, in which either the contour or the surface of the figure was degraded, using either partial occlusion (Experiment 1) or ramping (Experiments 2 and 3) of figure-ground differences. In each experiment, performance in luminance tasks was worst when the contour was degraded, whereas performance in chromaticity tasks was worst when the surface was degraded. This interaction was found even when spatial frequencies were fixed across test patterns by low-pass filtering. The results are consistent with a late (postfiltering) dual-mechanism system that processes luminance information to extract boundary representations and chromaticity information to extract surface representations.

High expression of ZNF703 independent of amplification indicates worse prognosis in patients with luminal B breast cancer

International Nuclear Information System (INIS)

Reynisdottir, Inga; Arason, Adalgeir; Einarsdottir, Berglind O; Gunnarsson, Haukur; Staaf, Johan; Vallon-Christersson, Johan; Jonsson, Goran; Ringnér, Markus; Agnarsson, Bjarni A; Olafsdottir, Kristrun; Fagerholm, Rainer; Einarsdottir, Thorbjorg; Johannesdottir, Gudrun; Johannsson, Oskar Thor; Nevanlinna, Heli; Borg, Ake; Barkardottir, Rosa Bjork

2013-01-01

Amplification of 8p12-p11 is relatively common in breast cancer and several genes within the region have been suggested to affect breast tumor progression. The aim of the study was to map the amplified 8p12-p11 region in a large set of breast tumors in an effort to identify the genetic driver and to explore its impact on tumor progression and prognosis. Copy number alterations (CNAs) were mapped in 359 tumors, and gene expression data from 577 tumors (359 tumors included) were correlated with CNA, clinical–pathological factors, and protein expression (39 tumors). 8p12-p11 was amplified in 11.4% of tumors. The smallest region of amplification harbored one full-length gene, ZNF703. ZNF703 mRNA expression was significantly higher in estrogen receptor (ER)-positive than ER-negative tumors (P = 2 × 10 −16 ), a reflection of high expression in luminal tumors. Forty-eight percent of tumors with ZNF703 amplification were luminal B tumors in which the best correlation between DNA copy number and mRNA was seen (P = 1.2 × 10 −7 ) as well as correlation between mRNA and protein expression (P = 0.02). High ZNF703 mRNA correlated with poor survival in patients with ER-positive luminal B tumors (log rank P = 0.04). Furthermore, high ZNF703 mRNA expression correlated with poor outcome in patients with ZNF703 copy number neutral, ER-positive, luminal B tumors (log rank P = 0.004). The results support ZNF703 as the driver gene of the 8p12 amplification and suggest that independent of amplification, high expression of the gene affects prognosis in luminal B tumors. Our mapping of 8p12-p11 and analyses of ZNF703 mRNA and protein expression in breast tumors support ZNF703 as an oncogene in luminal B tumors. High ZNF703 expression, independent of the amplification, correlated with worse prognosis for the breast cancer patients with ER-positive luminal tumors, particularly of the luminal B subtype

The ALHAMBRA survey: 2D analysis of the stellar populations in massive early-type galaxies at z < 0.3

Science.gov (United States)

San Roman, I.; Cenarro, A. J.; Díaz-García, L. A.; López-Sanjuan, C.; Varela, J.; González Delgado, R. M.; Sánchez-Blázquez, P.; Alfaro, E. J.; Ascaso, B.; Bonoli, S.; Borlaff, A.; Castander, F. J.; Cerviño, M.; Fernández-Soto, A.; Márquez, I.; Masegosa, J.; Muniesa, D.; Pović, M.; Viironen, K.; Aguerri, J. A. L.; Benítez, N.; Broadhurst, T.; Cabrera-Caño, J.; Cepa, J.; Cristóbal-Hornillos, D.; Infante, L.; Martínez, V. J.; Moles, M.; del Olmo, A.; Perea, J.; Prada, F.; Quintana, J. M.

2018-01-01

We present a technique that permits the analysis of stellar population gradients in a relatively low-cost way compared to integral field unit (IFU) surveys. We developed a technique to analyze unresolved stellar populations of spatially resolved galaxies based on photometric multi-filter surveys. This technique allows the analysis of vastly larger samples and out to larger galactic radii. We derived spatially resolved stellar population properties and radial gradients by applying a centroidal Voronoi tessellation and performing a multicolor photometry spectral energy distribution fitting. This technique has been successfully applied to a sample of 29 massive (M⋆ > 1010.5M⊙) early-type galaxies at z Max-Planck-Institut für Astronomie (MPIA) at Heidelberg and the Instituto de Astrofísica de Andalucía (CSIC).

Light production in the luminous fishes Photoblepharon and Anomalops from the Banda Islands.

Science.gov (United States)

Haneda, Y; Tsuji, F I

1971-07-09

The unresolved mechanism of light production in Photoblepharon and Anomalops has been reinvestigated in fresh and preserved material. Based on biochemical evidence obtained with emulsions and cell-free extracts of the organs, especially the stimulation of light with reduced flavin mononucleotide, and on electron microscopy of organ sections showing the presence of numerous bacteria, we conclude that the light is produced by symbiotic luminous bacteria. Because of the continuing failure to cultivate the luminous bacteria and because of their morphology, we suggest that the bacteria are of a primitive type called bacteroids.

A BUTTERFLY-SHAPED 'PAPILLON' NEBULA YIELDS SECRETS OF MASSIVE STAR BIRTH

Science.gov (United States)

2002-01-01

A NASA Hubble Space Telescope view of a turbulent cauldron of starbirth, called N159, taking place 170,000 light-years away in our satellite galaxy, the Large Magellanic Cloud (LMC). Torrential stellar winds from hot newborn massive stars within the nebula sculpt ridges, arcs, and filaments in the vast cloud, which is over 150 light-years across. A rare type of compact ionized 'blob' is resolved for the first time to be a butterfly-shaped or 'Papillon' (French for 'butterfly') nebula, buried in the center of the maelstrom of glowing gases and dark dust. The unprecedented details of the structure of the Papillon, itself less than 2 light-years in size (about 2 arcseconds in the sky), are seen in the inset. A possible explanation of this bipolar shape is the outflow of gas from massive stars (over 10 times the mass of our sun) hidden in the central absorption zone. Such stars are so hot that their radiation pressure halts the infall of gas and directs it away from the stars in two opposite directions. Presumably, a dense equatorial disk formed by matter still trying to fall in onto the stars focuses the outstreaming matter into the bipolar directions. This observation is part of a search for young massive stars in the LMC. Rare are the cases where we can see massive stars so early after their birth. The red in this true-color image is from the emission of hydrogen and the yellow from high excitation ionized oxygen. The picture was taken on September 5, 1998 with the Wide Field Planetary Camera 2. The Hubble observations of the Papillon nebula were conducted by the European astronomers Mohammad Heydari-Malayeri (Paris Observatory, France) and co-investigators Michael Rosa (Space Telescope-European Coordinating Facility, European Southern Observatory, Germany), Vassilis Charmandaris (Paris Observatory), Lise Deharveng (Marseille Observatory, France), and Hans Zinnecker (Astrophysical Institute, Potsdam, Germany). Their work is submitted for publication in the European

Low luminance/eyes closed and monochromatic stimulations reduce variability of flash visual evoked potential latency

Directory of Open Access Journals (Sweden)

Senthil Kumar Subramanian

2013-01-01

Full Text Available Context: Visual evoked potentials are useful in investigating the physiology and pathophysiology of the human visual system. Flash visual evoked potential (FVEP, though technically easier, has less clinical utility because it shows great variations in both latency and amplitude for normal subjects. Aim: To study the effect of eye closure, low luminance, and monochromatic stimulation on the variability of FVEPs. Subjects and Methods: Subjects in self-reported good health in the age group of 18-30 years were divided into three groups. All participants underwent FVEP recording with eyes open and with white light at 0.6 J luminance (standard technique. Next recording was done in group 1 with closed eyes, group 2 with 1.2 and 20 J luminance, and group 3 with red and blue lights, while keeping all the other parameters constant. Two trials were given for each eye, for each technique. The same procedure was repeated at the same clock time on the following day. Statistical Analysis: Variation in FVEP latencies between the individuals (interindividual variability and the variations within the same individual for four trials (intraindividual variability were assessed using coefficient of variance (COV. The technique with lower COV was considered the better method. Results: Recording done with closed eyes, 0.6 J luminance, and monochromatic light (blue > red showed lower interindividual and intraindividual variability in P2 and N2 as compared to standard techniques. Conclusions: Low luminance flash stimulations and monochromatic light will reduce FVEP latency variability and may be clinically useful modifications of FVEP recording technique.

Gemini long-slit observations of luminous obscured quasars: Further evidence for an upper limit on the size of the narrow-line region

International Nuclear Information System (INIS)

Hainline, Kevin N.; Hickox, Ryan C.; Greene, Jenny E.; Myers, Adam D.; Zakamska, Nadia L.; Liu, Guilin; Liu, Xin

2014-01-01

We examine the spatial extent of the narrow-line regions (NLRs) of a sample of 30 luminous obscured quasars at 0.4 < z < 0.7 observed with spatially resolved Gemini-N GMOS long-slit spectroscopy. Using the [O III] λ5007 emission feature, we estimate the size of the NLR using a cosmology-independent measurement: the radius where the surface brightness falls to 10 –15 erg s –1 cm –2 arcsec –2 . We then explore the effects of atmospheric seeing on NLR size measurements and conclude that direct measurements of the NLR size from observed profiles are too large by 0.1-0.2 dex on average, as compared to measurements made to best-fit Sérsic or Voigt profiles convolved with the seeing. These data, which span a full order of magnitude in IR luminosity (log (L 8 μm /erg s –1 ) = 44.4-45.4), also provide strong evidence that there is a flattening of the relationship between NLR size and active galactic nucleus luminosity at a seeing-corrected size of ∼7 kpc. The objects in this sample have high luminosities which place them in a previously under-explored portion of the size-luminosity relationship. These results support the existence of a maximal size of the NLR around luminous quasars; beyond this size, there is either not enough gas or the gas is over-ionized and does not produce enough [O III] λ5007 emission.

MicroRNA-139 suppresses proliferation in luminal type breast cancer cells by targeting Topoisomerase II alpha

Energy Technology Data Exchange (ETDEWEB)

Hua, Wei [Department of Obstetrics and Gynecology, Xijing Hospital, Fourth Military Medical University, Xi' an 710032 (China); State Key Laboratory of Cancer Biology, Department of Biochemistry and Molecular Biology, Fourth Military Medical University, 710032 Xi' an (China); Sa, Ke-Di; Zhang, Xiang; Jia, Lin-Tao; Zhao, Jing [State Key Laboratory of Cancer Biology, Department of Biochemistry and Molecular Biology, Fourth Military Medical University, 710032 Xi' an (China); Yang, An-Gang [State Key Laboratory of Cancer Biology, Department of Immunology, Fourth Military Medical University, 710032 Xi' an (China); Zhang, Rui, E-mail: ruizhang@fmmu.edu.cn [State Key Laboratory of Cancer Biology, Department of Biochemistry and Molecular Biology, Fourth Military Medical University, 710032 Xi' an (China); Fan, Jing, E-mail: jingfan@fmmu.edu.cn [Department of Vascular and Endocrine Surgery, Xijing Hospital, Fourth Military Medical University, Xi' an 710032 (China); Bian, Ka, E-mail: kakamax85@hotmail.com [State Key Laboratory of Cancer Biology, Department of Immunology, Fourth Military Medical University, 710032 Xi' an (China); Department of Otolaryngology, Tangdu Hospital, Fourth Military Medical University, Xi' an 710038 (China)

2015-08-07

The classification of molecular subtypes of breast cancer improves the prognostic accuracy and therapeutic benefits in clinic. However, because of the complexity of breast cancer, more biomarkers and functional molecules need to be explored. Here, analyzing the data in a huge cohort of breast cancer patients, we found that Topoisomerase II alpha (TOP2a), an important target of chemotherapy is a biomarker for prognosis in luminal type breast cancer patients, but not in basal like or HER2 positive breast cancer patients. We identified that miR-139, a previous reported anti-metastatic microRNA targets 3’-untranslated region (3′UTR) of TOP2a mRNA. Further more, we revealed that the forced expression of miR-139 reduces the TOP2a expression at both mRNA and protein levels. And our functional experiments showed that the ectopic expression of miR-139 remarkably inhibits proliferation in luminal type breast cancer cells, while exogenous TOP2a expression could rescue inhibition of cell proliferation mediated by miR-139. Collectively, our present study demonstrates the miR-139-TOP2a regulatory axis is important for proliferation in luminal type breast cancer cells. This functional link may help us to further understand the specificity of subtypes of breast cancer and optimize the strategy of cancer treatment. - Highlights: • High levels of TOP2a expression are closely associated with poor prognosis in luminal type breast cancer patients. • TOP2a is a novel target of miR-139. • Overexpression of miR-139 inhibits proliferation in luminal type breast cancer cells. • TOP2a is essential for miR-139-induced growth arrest in luminal type breast cancer cells.

MicroRNA-139 suppresses proliferation in luminal type breast cancer cells by targeting Topoisomerase II alpha

International Nuclear Information System (INIS)

Hua, Wei; Sa, Ke-Di; Zhang, Xiang; Jia, Lin-Tao; Zhao, Jing; Yang, An-Gang; Zhang, Rui; Fan, Jing; Bian, Ka

2015-01-01

The classification of molecular subtypes of breast cancer improves the prognostic accuracy and therapeutic benefits in clinic. However, because of the complexity of breast cancer, more biomarkers and functional molecules need to be explored. Here, analyzing the data in a huge cohort of breast cancer patients, we found that Topoisomerase II alpha (TOP2a), an important target of chemotherapy is a biomarker for prognosis in luminal type breast cancer patients, but not in basal like or HER2 positive breast cancer patients. We identified that miR-139, a previous reported anti-metastatic microRNA targets 3’-untranslated region (3′UTR) of TOP2a mRNA. Further more, we revealed that the forced expression of miR-139 reduces the TOP2a expression at both mRNA and protein levels. And our functional experiments showed that the ectopic expression of miR-139 remarkably inhibits proliferation in luminal type breast cancer cells, while exogenous TOP2a expression could rescue inhibition of cell proliferation mediated by miR-139. Collectively, our present study demonstrates the miR-139-TOP2a regulatory axis is important for proliferation in luminal type breast cancer cells. This functional link may help us to further understand the specificity of subtypes of breast cancer and optimize the strategy of cancer treatment. - Highlights: • High levels of TOP2a expression are closely associated with poor prognosis in luminal type breast cancer patients. • TOP2a is a novel target of miR-139. • Overexpression of miR-139 inhibits proliferation in luminal type breast cancer cells. • TOP2a is essential for miR-139-induced growth arrest in luminal type breast cancer cells

ALMA 1.3 Millimeter Map of the HD 95086 System -- A Young Analog of the HR 8799 System

Science.gov (United States)

Su, Kate; MacGregor, Meredith Ann; Booth, Mark; Wilner, David; Malhotra, Renu; Morrison, Sarah; OST STDT

2018-01-01

Planets and minor bodies such as asteroids, Kuiper-belt objects and comets are integral components of a planetary system. Interactions among them leave clues about the formation process of a planetary system. The signature of such interactions is best illustrated through resolved observations of its debris disk. Here we present ALMA 1.3 mm observations of HD 95086, a young analog of the HR 8799 system, that hosts a directly imaged giant planet b and a massive debris disk with both asteroid- and Kuiper-belt analogs. The location of the Kuiper-belt analog is resolved for the first time. Our deep ALMA map also reveals a bright source located near the edge of the ring. The properties of the source, based on limited data, are consistent with it being a luminous star-forming galaxy at high redshift. We will discuss future, resolved observations of debris disks, highlighting the potential of the Origins Space Telescope (OST), one of the four science and technology definition studies commissioned by NASA Headquarters for the 2020 Astronomy and Astrophysics Decadal survey.

The effects of age on visual perception of sine-wave gratings at low luminance / Os efeitos da idade na percepção visual de grades senoidais em luminância baixa

Directory of Open Access Journals (Sweden)

Natanael Antonio dos Santos

2006-01-01

Full Text Available The aim of this work was to investigate the contrast sensitivity function for sine-wave gratings in the range between 0.25-2 cpd in young and older adults (20-23, 30-39, 40-49, 50-59, 60-69 years old using low luminance. All subjects were free from identifiable ocular disease and had normal acuity. We measured the contrast thresholds for 30 participants (six volunteers in each age using the psychophysical forced-choice staircase method. In this method the volunteers had to choose the stimulus containing a test frequency at low contrast (e.g., a sine-wave grating, or another neutral stimulus at mean luminance (0.7 cd/m2. The results showed significant changes of CSF for sine-wave gratings at 1 and 2 cpd for the adults 50-59 and 60-69 years old compared to the adults of 20-23 years old. These results suggest age-related changes in the CSF for sine-wave grating at low luminance levels.

Photobacterium kishitanii sp. nov., a luminous marine bacterium symbiotic with deep-sea fishes.

Science.gov (United States)

Ast, Jennifer C; Cleenwerck, Ilse; Engelbeen, Katrien; Urbanczyk, Henryk; Thompson, Fabiano L; De Vos, Paul; Dunlap, Paul V

2007-09-01

Six representatives of a luminous bacterium commonly found in association with deep, cold-dwelling marine fishes were isolated from the light organs and skin of different fish species. These bacteria were Gram-negative, catalase-positive, and weakly oxidase-positive or oxidase-negative. Morphologically, cells of these strains were coccoid or coccoid-rods, occurring singly or in pairs, and motile by means of polar flagellation. After growth on seawater-based agar medium at 22 degrees C for 18 h, colonies were small, round and white, with an intense cerulean blue luminescence. Analysis of 16S rRNA gene sequence similarity placed these bacteria in the genus Photobacterium. Phylogenetic analysis based on seven housekeeping gene sequences (16S rRNA gene, gapA, gyrB, pyrH, recA, rpoA and rpoD), seven gene sequences of the lux operon (luxC, luxD, luxA, luxB, luxF, luxE and luxG) and four gene sequences of the rib operon (ribE, ribB, ribH and ribA), resolved the six strains as members of the genus Photobacterium and as a clade distinct from other species of Photobacterium. These strains were most closely related to Photobacterium phosphoreum and Photobacterium iliopiscarium. DNA-DNA hybridization values between the designated type strain, Photobacterium kishitanii pjapo.1.1(T), and P. phosphoreum LMG 4233(T), P. iliopiscarium LMG 19543(T) and Photobacterium indicum LMG 22857(T) were 51, 43 and 19 %, respectively. In AFLP analysis, the six strains clustered together, forming a group distinct from other analysed species. The fatty acid C(17 : 0) cyclo was present in these bacteria, but not in P. phosphoreum, P. iliopiscarium or P. indicum. A combination of biochemical tests (arginine dihydrolase and lysine decarboxylase) differentiates these strains from P. phosphoreum and P. indicum. The DNA G+C content of P. kishitanii pjapo.1.1(T) is 40.2 %, and the genome size is approximately 4.2 Mbp, in the form of two circular chromosomes. These strains represent a novel species, for

Radiative transfer modelling of W33A MM1: 3-D structure and dynamics of a complex massive star forming region

Science.gov (United States)

Izquierdo, Andrés F.; Galván-Madrid, Roberto; Maud, Luke T.; Hoare, Melvin G.; Johnston, Katharine G.; Keto, Eric R.; Zhang, Qizhou; de Wit, Willem-Jan

2018-05-01

We present a composite model and radiative transfer simulations of the massive star forming core W33A MM1. The model was tailored to reproduce the complex features observed with ALMA at ≈0.2 arcsec resolution in CH3CN and dust emission. The MM1 core is fragmented into six compact sources coexisting within ˜1000 au. In our models, three of these compact sources are better represented as disc-envelope systems around a central (proto)star, two as envelopes with a central object, and one as a pure envelope. The model of the most prominent object (Main) contains the most massive (proto)star (M⋆ ≈ 7 M⊙) and disc+envelope (Mgas ≈ 0.4 M⊙), and is the most luminous (LMain ˜ 104 L⊙). The model discs are small (a few hundred au) for all sources. The composite model shows that the elongated spiral-like feature converging to the MM1 core can be convincingly interpreted as a filamentary accretion flow that feeds the rising stellar system. The kinematics of this filament is reproduced by a parabolic trajectory with focus at the center of mass of the region. Radial collapse and fragmentation within this filament, as well as smaller filamentary flows between pairs of sources are proposed to exist. Our modelling supports an interpretation where what was once considered as a single massive star with a ˜103 au disc and envelope, is instead a forming stellar association which appears to be virialized and to form several low-mass stars per high-mass object.

Left bronchial artery arising from a replaced left hepatic artery in a patient with massive hemoptysis

Energy Technology Data Exchange (ETDEWEB)

Khil, Eun Kyung; Lee, Jae Myung [Dept. of Radiology, Soonchunhyang University College of Medicine, Bucheon Hospital, Bucheon (Korea, Republic of)

2015-09-15

A 70-year-old man with a 3-year history of bronchiectasis presented with massive hemoptysis that had lasted for 3 days. In our attempt to perform bronchial artery embolization, upper abdominal angiography was required to locate the left bronchial artery, which in this case was of anomalous origin, arising from a replaced left hepatic artery, which arose from the left gastric artery-a very unusual anatomical variant. We performed embolization with polyvinyl alcohol particles, and the patient's symptoms resolved completely, with no additional complications after conservative treatment.

10 CFR 32.22 - Self-luminous products containing tritium, krypton-85 or promethium-147: Requirements for license...

Science.gov (United States)

2010-01-01

... 10 Energy 1 2010-01-01 2010-01-01 false Self-luminous products containing tritium, krypton-85 or... containing tritium, krypton-85 or promethium-147: Requirements for license to manufacture, process, produce... self-luminous products containing tritium, krypton-85, or promethium-147, or to initially transfer such...

Dynamic contrast-enhanced MRI in patients with luminal Crohn's disease

NARCIS (Netherlands)

Ziech, M. L. W.; Lavini, C.; Caan, M. W. A.; Nio, C. Y.; Stokkers, P. C. F.; Bipat, S.; Ponsioen, C. Y.; Nederveen, A. J.; Stoker, J.

2012-01-01

Objectives: To prospectively assess dynamic contrast-enhanced (DCE-)MRI as compared to conventional sequences in patients with luminal Crohn's disease. Methods: Patients with Crohn's disease undergoing MRI and ileocolonoscopy within 1 month had DCE-MRI (3T) during intravenous contrast injection of

THE ATACAMA COSMOLOGY TELESCOPE: ACT-CL J0102–4915 'EL GORDO', A MASSIVE MERGING CLUSTER AT REDSHIFT 0.87

International Nuclear Information System (INIS)

Menanteau, Felipe; Hughes, John P.; Baker, Andrew J.; Sifón, Cristóbal; González, Jorge; Infante, Leopoldo; Felipe Barrientos, L.; Hilton, Matt; Bond, John R.; Hajian, Amir; Nolta, Michael R.; Das, Sudeep; Devlin, Mark J.; Marsden, Danica; Dunkley, Joanna; Hincks, Adam D.; Kosowsky, Arthur; Marriage, Tobias A.; Moodley, Kavilan; Niemack, Michael D.

2012-01-01

We present a detailed analysis from new multi-wavelength observations of the exceptional galaxy cluster ACT-CL J0102–4915, likely the most massive, hottest, most X-ray luminous and brightest Sunyaev-Zel'dovich (SZ) effect cluster known at redshifts greater than 0.6. The Atacama Cosmology Telescope (ACT) collaboration discovered ACT-CL J0102–4915 as the most significant SZ decrement in a sky survey area of 755 deg 2 . Our Very Large Telescope (VLT)/FORS2 spectra of 89 member galaxies yield a cluster redshift, z = 0.870, and velocity dispersion, σ gal = 1321 ± 106 km s –1 . Our Chandra observations reveal a hot and X-ray luminous system with an integrated temperature of T X = 14.5 ± 0.1 keV and 0.5-2.0 keV band luminosity of L X = (2.19 ± 0.11) × 10 45 h –2 70 erg s –1 . We obtain several statistically consistent cluster mass estimates; using empirical mass scaling relations with velocity dispersion, X-ray Y X , and integrated SZ distortion, we estimate a cluster mass of M 200a = (2.16 ± 0.32) × 10 15 h –1 70 M ☉ . We constrain the stellar content of the cluster to be less than 1% of the total mass, using Spitzer IRAC and optical imaging. The Chandra and VLT/FORS2 optical data also reveal that ACT-CL J0102–4915 is undergoing a major merger between components with a mass ratio of approximately 2 to 1. The X-ray data show significant temperature variations from a low of 6.6 ± 0.7 keV at the merging low-entropy, high-metallicity, cool core to a high of 22 ± 6 keV. We also see a wake in the X-ray surface brightness and deprojected gas density caused by the passage of one cluster through the other. Archival radio data at 843 MHz reveal diffuse radio emission that, if associated with the cluster, indicates the presence of an intense double radio relic, hosted by the highest redshift cluster yet. ACT-CL J0102–4915 is possibly a high-redshift analog of the famous Bullet cluster. Such a massive cluster at this redshift is rare, although consistent

Development and construction of a programmable generator of luminous impulses

International Nuclear Information System (INIS)

Sahuc, P.

1989-01-01

The design and construction of an impulse generator, for light waves, designed to control the characteristics of a scintillator. In these detectors, a particle gives rise to the emission of a luminous signal, which must be transformed in an electrical signal. In the present work, photomultipliers are used as luminous-electrical signal converters. The principles of operation of a scintillator, of a scintillator connected with a photodiode, and of a scintillator connected with a photomultiplier are reviewed. The analysis of the performance and of the possibilies offered by the usual generators of light, show that more suitable solutions are required. The characteristics of the electroluminescent diodes, their performances, concerning light emission and power, are investigated. The principles, the operating conditions and the performances of a generator of light, applying electroluminescent diodes, are examined. The construction and the results obtained with a prototype are presented [fr

Nonsingular universe in massive gravity's rainbow

Science.gov (United States)

Hendi, S. H.; Momennia, M.; Eslam Panah, B.; Panahiyan, S.

2017-06-01

One of the fundamental open questions in cosmology is whether we can regard the universe evolution without singularity like a Big Bang or a Big Rip. This challenging subject stimulates one to regard a nonsingular universe in the far past with an arbitrarily large vacuum energy. Considering the high energy regime in the cosmic history, it is believed that Einstein gravity should be corrected to an effective energy dependent theory which could be acquired by gravity's rainbow. On the other hand, employing massive gravity provided us with solutions to some of the long standing fundamental problems of cosmology such as cosmological constant problem and self acceleration of the universe. Considering these aspects of gravity's rainbow and massive gravity, in this paper, we initiate studying FRW cosmology in the massive gravity's rainbow formalism. At first, we show that although massive gravity modifies the FRW cosmology, but it does not itself remove the big bang singularity. Then, we generalize the massive gravity to the case of energy dependent spacetime and find that massive gravity's rainbow can remove the early universe singularity. We bring together all the essential conditions for having a nonsingular universe and the effects of both gravity's rainbow and massive gravity generalizations on such criteria are determined.

Profile of a Growing Urban School: The Lumin Experience

Science.gov (United States)

Ford, Terry

2015-01-01

This fairytale-come-true began with an idealistic public school teacher just out of college who lived in the neighborhood of her students. In stages, working with a community organizing group consisting mainly of concerned parents, Terry Ford founded what is now called Lumin Education, a network of campuses serving more than six hundred children…

Discovery of GeV emission from the direction of the luminous infrared galaxy NGC 2146

Energy Technology Data Exchange (ETDEWEB)

Tang, Qing-Wen; Wang, Xiang-Yu [School of Astronomy and Space Science, Nanjing University, Nanjing, 210093 (China); Thomas Tam, Pak-Hin, E-mail: xywang@nju.edu.cn, E-mail: phtam@phys.nthu.edu.tw [Institute of Astronomy and Department of Physics, National Tsing Hua University, Hsinchu 30013, Taiwan (China)

2014-10-10

Recent detections of high-energy gamma-ray emission from starburst galaxies M82 and NGC 253 suggest that starburst galaxies are huge reservoirs of cosmic rays and these cosmic rays convert a significant fraction of their energy into gamma-rays by colliding with the dense interstellar medium. In this paper, we report the search for high-energy gamma-ray emission from several nearby star-forming and starburst galaxies using the 68 month data obtained with the Fermi Large Area Telescope. We found a ∼5.5σ detection of gamma-ray emission above 200 MeV from a source spatially coincident with the location of the luminous infrared galaxy NGC 2146. Also taking into account the temporal and spectral properties of the gamma-ray emission, we suggest that the gamma-ray source is likely to be the counterpart of NGC 2146. The gamma-ray luminosity suggests that cosmic rays in NGC 2146 convert most of their energy into secondary pions, so NGC 2146 is a 'proton calorimeter'. It is also found that NGC 2146 obeys the quasi-linear scaling relation between gamma-ray luminosity and total infrared luminosity for star-forming galaxies, strengthening the connection between massive star formation and gamma-ray emission of star-forming galaxies. Possible TeV emission from NGC 2146 is predicted and the implications for high-energy neutrino emission from starburst galaxies are discussed.

Massive propagators in instanton fields

International Nuclear Information System (INIS)

Brown, L.S.; Lee, C.

1978-01-01

Green's functions for massive spinor and vector particles propagating in a self-dual but otherwise arbitrary non-Abelian gauge field are shown to be completely determined by the corresponding Green's functions of massive scalar particles

Modulation of visual cortical excitability by working memory: effect of luminance contrast of mental imagery

Directory of Open Access Journals (Sweden)

Zaira eCattaneo

2011-02-01

Full Text Available Although much is known about the impact of stimulus properties such as luminance contrast, spatial frequency and orientation on visually evoked neural activity, much less is known about how they modulate neural activity when they are properties of a mental image held in working memory (WM. Here we addressed this question by investigating how a parametric manipulation of an imagined stimulus attribute affects neuronal excitability in the early visual cortex. We manipulated luminance contrast, a stimulus property known to strongly affect the magnitude of neuronal responses in early visual areas. Luminance contrast modulated neuronal excitability, as assessed by the frequency of phosphenes induced by transcranial magnetic stimulation (TMS with the exact nature of this modulation depending on TMS intensity. These results point to a strong overlap in the neuronal processes underlying visual perception and mental imagery: not only does WM maintenance selectively engage neurons which are tuned to the maintained attribute (as has previously been shown, but the extent to which those neurons are activated depends on the luminance contrast (as is the case with visually-evoked responses. From a methodological viewpoint, these results suggest that assessment of visual cortical excitability using TMS is affected by the TMS intensity used to probe the neuronal population.

Contributions of contour frequency, amplitude, and luminance to the watercolor effect estimated by conjoint measurement.

Science.gov (United States)

Gerardin, Peggy; Devinck, Frédéric; Dojat, Michel; Knoblauch, Kenneth

2014-04-10

The watercolor effect is a long-range, assimilative, filling-in phenomenon induced by a pair of distant, wavy contours of different chromaticities. Here, we measured joint influences of the contour frequency and amplitude and the luminance of the interior contour on the strength of the effect. Contour pairs, each enclosing a circular region, were presented with two of the dimensions varying independently across trials (luminance/frequency, luminance/amplitude, frequency/amplitude) in a conjoint measurement paradigm (Luce & Tukey, 1964). In each trial, observers judged which of the stimuli evoked the strongest fill-in color. Control stimuli were identical except that the contours were intertwined and generated little filling-in. Perceptual scales were estimated by a maximum likelihood method (Ho, Landy, & Maloney, 2008). An additive model accounted for the joint contributions of any pair of dimensions. As shown previously using difference scaling (Devinck & Knoblauch, 2012), the strength increases with luminance of the interior contour. The strength of the phenomenon was nearly independent of the amplitude of modulation of the contour but increased with its frequency up to an asymptotic level. On average, the strength of the effect was similar along a given dimension regardless of the other dimension with which it was paired, demonstrating consistency of the underlying estimated perceptual scales.

Compact RGBY light sources with high luminance for laser display applications

Science.gov (United States)

Paschke, Katrin; Blume, Gunnar; Werner, Nils; Müller, André; Sumpf, Bernd; Pohl, Johannes; Feise, David; Ressel, Peter; Sahm, Alexander; Bege, Roland; Hofmann, Julian; Jedrzejczyk, Daniel; Tränkle, Günther

2018-02-01

Watt-class visible laser light with a high luminance can be created with high-power GaAs-based lasers either directly in the red spectral region or using single-pass second harmonic generation (SHG) for the colors in the blue-yellow spectral region. The concepts and results of red- and near infrared-emitting distributed Bragg reflector tapered lasers and master oscillator power amplifier systems as well as their application for SHG bench-top experiments and miniaturized modules are presented. Examples of these high-luminance light sources aiming at different applications such as flying spot display or holographic 3D cinema are discussed in more detail. The semiconductor material allows an easy adaptation of the wavelength allowing techniques such as six-primary color 3D projection or color space enhancement by adding a fourth yellow color.

First observations of transient luminous events in Indian sub-continent

DEFF Research Database (Denmark)

Singh, Rajesh; Maurya, Ajeet K.; Veenadhari, B.

2014-01-01

The article offers information on the initial observations of flashes of lightning discharge observed above thunderstorms. It mentions that the transient luminous events (TLE) are classified on the basis of their geometrical shape and luminosity into Sprites, Halos and Blue Starters. It also focu...

Topologically massive supergravity

Directory of Open Access Journals (Sweden)

S. Deser

1983-01-01

Full Text Available The locally supersymmetric extension of three-dimensional topologically massive gravity is constructed. Its fermionic part is the sum of the (dynamically trivial Rarita-Schwinger action and a gauge-invariant topological term, of second derivative order, analogous to the gravitational one. It is ghost free and represents a single massive spin 3/2 excitation. The fermion-gravity coupling is minimal and the invariance is under the usual supergravity transformations. The system's energy, as well as that of the original topological gravity, is therefore positive.

The essential signature of a massive starburst in a distant quasar.

Science.gov (United States)

Solomon, P; Vanden Bout, P; Carilli, C; Guelin, M

2003-12-11

Observations of carbon monoxide emission in high-redshift (zeta > 2) galaxies indicate the presence of large amounts of molecular gas. Many of these galaxies contain an active galactic nucleus powered by accretion of gas onto a supermassive black hole, and a key question is whether their extremely high infrared luminosities result from the active galactic nucleus, from bursts of massive star formation (associated with the molecular gas), or both. In the Milky Way, high-mass stars form in the dense cores of interstellar molecular clouds, where gas densities are n(H2) > 10(5) cm(-3) (refs 1, 2). Recent surveys show that virtually all galactic sites of high-mass star formation have similarly high densities. The bulk of the cloud material traced by CO observations, however, is at a much lower density. For galaxies in the local Universe, the HCN molecule is an effective tracer of high-density molecular gas. Here we report observations of HCN emission from the infrared-luminous 'Cloverleaf' quasar (at a redshift zeta = 2.5579). The HCN line luminosity indicates the presence of 10 billion solar masses of very dense gas, an essential feature of an immense starburst, which contributes, together with the active galactic nucleus it harbours, to its high infrared luminosity.

Selected luminal mucosal complications of adult celiac disease

OpenAIRE

Freeman, Hugh

2009-01-01

Hugh J FreemanDepartment of Medicine (Gastroenterology), University of British Columbia, Vancouver, BC, CanadaAbstract: Celiac disease is a gluten-dependent intestinal disorder that appears to be associated with several clinical conditions. Some involve the luminal mucosa of the stomach and intestinal tract and may, occasionally, complicate the course of celiac disease. Collagenous colitis has been associated with celiac disease and may lead to chronic diarrhea. Conversely, some of t...

The Dichotomous Cosmology with a Static Material World and Expanding Luminous World

Directory of Open Access Journals (Sweden)

Heymann Y.

2014-07-01

Full Text Available The dichotomous cosmology is an alternative to the expanding Universe theory, and consists of a static matter Universe, where cosmological redshifts are explained by a tired-light model with an expanding luminous world. In this model the Hubble constant is also the photon energy decay rate, and the luminous world i s expanding at a constant rate as in de Sitter cosmology for an empty Universe. The present model explains both the luminosity distance versus redshift relationship of supernovae Ia, and ageing of spectra observed with the stretching of supernovae light curves. Furthermore, it is consistent with a radiation energy density factor (1 + z 4 inferred from the Cosmic Microwave Background Radiation.

Quantitative bronchial luminal volumetric assessment of pulmonary function loss by thin-section MDCT in pulmonary emphysema patients

International Nuclear Information System (INIS)

Koyama, Hisanobu; Ohno, Yoshiharu; Yamazaki, Youichi; Onishi, Yumiko; Takenaka, Daisuke; Yoshikawa, Takeshi; Nishio, Mizuho; Matsumoto, Sumiaki; Murase, Kenya; Nishimura, Yoshihiro; Sugimura, Kazuro

2012-01-01

Objectives: To determine the capability of quantitative bronchial luminal volume to assess pulmonary function loss and disease severity in pulmonary emphysema patients. Methods: Thirty-seven smokers (mean age, 68.1 years) underwent CT examinations and pulmonary function tests. For the quantitative assessment, luminal voxels of trachea and bronchi were computationally counted and the ratio of the following luminal voxels to all luminal voxels was obtained: (1) the lobe bronchi and the peripheral bronchi (Ratio lobe ), and (2) the main bronchi and the peripheral bronchi (Ratio main ). To determine the capability of these assessments to predict pulmonary function loss, these ratios were correlated with pulmonary function tests. To determine the capability for predicting disease severity, these ratios were compared between clinical groups. Results: These ratios were no significant correlated with vital capacity and forced vital capacity (FVC) (p > 0.05), however significantly correlated with forced expiratory volume in 1 s (FEV1) (Ratio lobe : r = 0.61, p main : r = 0.58, p lobe : r = 0.36, p main : r = 0.33, p lobe of smokers without COPD was significantly different from those of moderate COPD and severe or very severe COPD (p main of severe or very severe COPD patients was significantly different from those of other groups (p < 0.05). Conclusions: Quantitative bronchial luminal volumes were reflected the airflow limitation parameters and was corresponded to clinical groups in emphysema patients.

Might dark matter not be concentric with luminous matter

International Nuclear Information System (INIS)

Xu Chongming; Lu Tan.

1986-12-01

In this paper, an idea on dark matter nonconcentric with luminous matter is proposed. This case could influence the rotation curve of galaxy differently in its different direction. Recently, Rubin and Ford's observation on rotation curve of Hickson 88a has been explained by means of the idea. Some possible observational predictions have also been given. (author)

Spacetime structure of massive Majorana particles and massive gravitino

Energy Technology Data Exchange (ETDEWEB)

Ahluwalia, D.V.; Kirchbach, M. [Theoretical Physics Group, Facultad de Fisica, Universidad Autonoma de Zacatecas, A.P. 600, 98062 Zacatecas (Mexico)

2003-07-01

The profound difference between Dirac and Majorana particles is traced back to the possibility of having physically different constructs in the (1/2, 0) 0 (0,1/2) representation space. Contrary to Dirac particles, Majorana-particle propagators are shown to differ from the simple linear {gamma} {mu} p{sub {mu}}, structure. Furthermore, neither Majorana particles, nor their antiparticles can be associated with a well defined arrow of time. The inevitable consequence of this peculiarity is the particle-antiparticle metamorphosis giving rise to neutrinoless double beta decay, on the one side, and enabling spin-1/2 fields to act as gauge fields, gauginos, on the other side. The second part of the lecture notes is devoted to massive gravitino. We argue that a spin measurement in the rest frame for an unpolarized ensemble of massive gravitino, associated with the spinor-vector [(1/2, 0) 0 (0,1/2)] 0 (1/2,1/2) representation space, would yield the results 3/2 with probability one half, and 1/2 with probability one half. The latter is distributed uniformly, i.e. as 1/4, among the two spin-1/2+ and spin-1/2- states of opposite parities. From that we draw the conclusion that the massive gravitino should be interpreted as a particle of multiple spin. (Author)

Search of massive star formation with COMICS

Science.gov (United States)

Okamoto, Yoshiko K.

2004-04-01

Mid-infrared observations is useful for studies of massive star formation. Especially COMICS offers powerful tools: imaging survey of the circumstellar structures of forming massive stars such as massive disks and cavity structures, mass estimate from spectroscopy of fine structure lines, and high dispersion spectroscopy to census gas motion around formed stars. COMICS will open the next generation infrared studies of massive star formation.

Mechanical feedback in the molecular ISM of luminous IR galaxies

NARCIS (Netherlands)

Loenen, A. F.; Spaans, M.; Baan, W. A.; Meijerink, R.

Aims. Molecular emission lines originating in the nuclei of luminous infra-red galaxies are used to determine the physical properties of the nuclear ISM in these systems. Methods. A large observational database of molecular emission lines is compared with model predictions that include heating by UV

Persistent X-Ray Emission from ASASSN-15lh: Massive Ejecta and Pre-SLSN Dense Wind?

Science.gov (United States)

Huang, Yan; Li, Zhuo

2018-06-01

The persistent soft X-ray emission from the location of the most luminous supernova (SN) so far, ASASSN-15lh (or SN 2015L), with L∼ {10}42 {erg} {{{s}}}-1, is puzzling. We show that it can be explained by radiation from electrons accelerated by the SN shock inverse-Compton scattering the intense UV photons. The non-detection in radio requires strong free–free absorption in the dense medium. In these interpretations, the circumstellar medium is derived to be a wind (n ∝ R ‑2) with mass-loss rate of \\dot{{M}}≳ 3× {10}-3{{M}}ȯ ({{v}}{{w}}/{10}3 {{k}}{{m}} {{{s}}}-1) {{{y}}{{r}}}-1, and the initial velocity of the bulk SN ejecta is ≲ 0.02c. These constraints imply a massive ejecta mass of ≳ 60({E}0/2× {10}52 {erg}){M}ȯ in ASASSN-15lh, and a strong wind ejected by the progenitor star within ∼ 8{({v}{{w}}/{10}3{km}{{{s}}}-1)}-1 yr before explosion.

ORIGIN AND GROWTH OF NUCLEAR STAR CLUSTERS AROUND MASSIVE BLACK HOLES

International Nuclear Information System (INIS)

Antonini, Fabio

2013-01-01

The centers of stellar spheroids less luminous than ∼10 10 L ☉ are often marked by the presence of nucleated central regions, called 'nuclear star clusters' (NSCs). The origin of NSCs is still unclear. Here we investigate the possibility that NSCs originate from the migration and merger of stellar clusters at the center of galaxies where a massive black hole (MBH) may sit. We show that the observed scaling relation between NSC masses and the velocity dispersion of their host spheroids cannot be reconciled with a purely 'in situ' dissipative formation scenario. On the other hand, the observed relation appears to be in agreement with the predictions of the cluster merger model. A dissipationless formation model also reproduces the observed relation between the size of NSCs and their total luminosity, R∝√(L NSC ). When an MBH is included at the center of the galaxy, such dependence becomes substantially weaker than the observed correlation, since the size of the NSC is mainly determined by the fixed tidal field of the MBH. We evolve through dynamical friction a population of stellar clusters in a model of a galactic bulge taking into account dynamical dissolution due to two-body relaxation, starting from a power-law cluster initial mass function and adopting an initial total mass in stellar clusters consistent with the present-day cluster formation efficiency of the Milky Way (MW). The most massive clusters reach the center of the galaxy and merge to form a compact nucleus; after 10 10 years, the resulting NSC has properties that are consistent with the observed distribution of stars in the MW NSC. When an MBH is included at the center of a galaxy, globular clusters are tidally disrupted during inspiral, resulting in NSCs with lower densities than those of NSCs forming in galaxies with no MBHs. We suggest this as a possible explanation for the lack of NSCs in galaxies containing MBHs more massive than ∼10 8 M ☉ . Finally, we investigate the orbital

ORIGIN AND GROWTH OF NUCLEAR STAR CLUSTERS AROUND MASSIVE BLACK HOLES

Energy Technology Data Exchange (ETDEWEB)

Antonini, Fabio, E-mail: antonini@cita.utoronto.ca [Canadian Institute for Theoretical Astrophysics, University of Toronto, 60 St. George Street, Toronto, Ontario M5S 3H8 (Canada)

2013-01-20

The centers of stellar spheroids less luminous than {approx}10{sup 10} L {sub Sun} are often marked by the presence of nucleated central regions, called 'nuclear star clusters' (NSCs). The origin of NSCs is still unclear. Here we investigate the possibility that NSCs originate from the migration and merger of stellar clusters at the center of galaxies where a massive black hole (MBH) may sit. We show that the observed scaling relation between NSC masses and the velocity dispersion of their host spheroids cannot be reconciled with a purely 'in situ' dissipative formation scenario. On the other hand, the observed relation appears to be in agreement with the predictions of the cluster merger model. A dissipationless formation model also reproduces the observed relation between the size of NSCs and their total luminosity, R{proportional_to}{radical}(L{sub NSC}). When an MBH is included at the center of the galaxy, such dependence becomes substantially weaker than the observed correlation, since the size of the NSC is mainly determined by the fixed tidal field of the MBH. We evolve through dynamical friction a population of stellar clusters in a model of a galactic bulge taking into account dynamical dissolution due to two-body relaxation, starting from a power-law cluster initial mass function and adopting an initial total mass in stellar clusters consistent with the present-day cluster formation efficiency of the Milky Way (MW). The most massive clusters reach the center of the galaxy and merge to form a compact nucleus; after 10{sup 10} years, the resulting NSC has properties that are consistent with the observed distribution of stars in the MW NSC. When an MBH is included at the center of a galaxy, globular clusters are tidally disrupted during inspiral, resulting in NSCs with lower densities than those of NSCs forming in galaxies with no MBHs. We suggest this as a possible explanation for the lack of NSCs in galaxies containing MBHs more massive

On maximal massive 3D supergravity

OpenAIRE

Bergshoeff , Eric A; Hohm , Olaf; Rosseel , Jan; Townsend , Paul K

2010-01-01

ABSTRACT We construct, at the linearized level, the three-dimensional (3D) N = 4 supersymmetric " general massive supergravity " and the maximally supersymmetric N = 8 " new massive supergravity ". We also construct the maximally supersymmetric linearized N = 7 topologically massive supergravity, although we expect N = 6 to be maximal at the non-linear level. (Bergshoeff, Eric A) (Hohm, Olaf) (Rosseel, Jan) P.K.Townsend@da...

Null stream analysis of Pulsar Timing Array data: localisation of resolvable gravitational wave sources

Science.gov (United States)

Goldstein, Janna; Veitch, John; Sesana, Alberto; Vecchio, Alberto

2018-04-01

Super-massive black hole binaries are expected to produce a gravitational wave (GW) signal in the nano-Hertz frequency band which may be detected by pulsar timing arrays (PTAs) in the coming years. The signal is composed of both stochastic and individually resolvable components. Here we develop a generic Bayesian method for the analysis of resolvable sources based on the construction of `null-streams' which cancel the part of the signal held in common for each pulsar (the Earth-term). For an array of N pulsars there are N - 2 independent null-streams that cancel the GW signal from a particular sky location. This method is applied to the localisation of quasi-circular binaries undergoing adiabatic inspiral. We carry out a systematic investigation of the scaling of the localisation accuracy with signal strength and number of pulsars in the PTA. Additionally, we find that source sky localisation with the International PTA data release one is vastly superior than what is achieved by its constituent regional PTAs.

Grain formation in the expanding gas flow around cool luminous stars

International Nuclear Information System (INIS)

Hasegawa, H.

1984-01-01

The existence of solid particles in interstellar space has been revealed by the extinction of starlight in UV, visible and IR. The important sources of interstellar grains are considered to be cool luminous mass loss stars. (author)

Calcium reduces the sodium permeability of luminal membrane vesicles from toad bladder. Studies using a fast-reaction apparatus

International Nuclear Information System (INIS)

Chase, H.S. Jr.; Al-Awqati, Q.

1983-01-01

Regulation of the sodium permeability of the luminal membrane is the major mechanism by which the net rate of sodium transport across tight epithelia is varied. Previous evidence has suggested that the permeability of the luminal membrane might be regulated by changes in intracellular sodium or calcium activities. To test this directly, we isolated a fraction of the plasma membrane from the toad urinary bladder, which contains a fast, amiloride-sensitive sodium flux with characteristics similar to those of the native luminal membrane. Using a flow-quench apparatus to measure the initial rate of sodium efflux from these vesicles in the millisecond time range, we have demonstrated that the isotope exchange permeability of these vesicles is very sensitive to calcium. Calcium reduces the sodium permeability, and the half-maximal inhibitory concentration is 0.5 microM, well within the range of calcium activity found in cells. Also, the permeability of the luminal membrane vesicles is little affected by the ambient sodium concentration. These results, when taken together with studies on whole tissue, suggest that cell calcium may be an important regulator of transepithelial sodium transport by its effect on luminal sodium permeability. The effect of cell sodium on permeability may be mediated by calcium rather than by sodium itself

Surface regions of illusory images are detected with a slower processing speed than those of luminance-defined images.

Science.gov (United States)

Mihaylova, Milena; Manahilov, Velitchko

2010-11-24

Research has shown that the processing time for discriminating illusory contours is longer than for real contours. We know, however, little whether the visual processes, associated with detecting regions of illusory surfaces, are also slower as those responsible for detecting luminance-defined images. Using a speed-accuracy trade-off (SAT) procedure, we measured accuracy as a function of processing time for detecting illusory Kanizsa-type and luminance-defined squares embedded in 2D static luminance noise. The data revealed that the illusory images were detected at slower processing speed than the real images, while the points in time, when accuracy departed from chance, were not significantly different for both stimuli. The classification images for detecting illusory and real squares showed that observers employed similar detection strategies using surface regions of the real and illusory squares. The lack of significant differences between the x-intercepts of the SAT functions for illusory and luminance-modulated stimuli suggests that the detection of surface regions of both images could be based on activation of a single mechanism (the dorsal magnocellular visual pathway). The slower speed for detecting illusory images as compared to luminance-defined images could be attributed to slower processes of filling-in of regions of illusory images within the dorsal pathway.

Development and Application of a Microfluidics-Based Panel in the Basal/Luminal Transcriptional Characterization of Archival Bladder Cancers.

Directory of Open Access Journals (Sweden)

Doris Kim

Full Text Available In the age of personalized medicine stratifying tumors into molecularly defined subtypes associated with distinctive clinical behaviors and predictable responses to therapies holds tremendous value. Towards this end, we developed a custom microfluidics-based bladder cancer gene expression panel for characterization of archival clinical samples. In silico analysis indicated that the content of our panel was capable of accurately segregating bladder cancers from several public datasets into the clinically relevant basal and luminal subtypes. On a technical level, our bladder cancer panel yielded robust and reproducible results when analyzing formalin-fixed, paraffin-embedded (FFPE tissues. We applied our panel in the analysis of a novel set of 204 FFPE samples that included non-muscle invasive bladder cancers (NMIBCs, muscle invasive disease (MIBCs, and bladder cancer metastases (METs. We found NMIBCs to be mostly luminal-like, MIBCs to include both luminal- and basal-like types, and METs to be predominantly of a basal-like transcriptional profile. Mutational analysis confirmed the expected enrichment of FGFR3 mutations in luminal samples, and, consistently, FGFR3 IHC showed high protein expression levels of the receptor in these tumors. Our bladder cancer panel enables basal/luminal characterization of FFPE tissues and with further development could be used for stratification of bladder cancer samples in the clinic.

MN112: a new Galactic candidate luminous blue variable

Science.gov (United States)

Gvaramadze, V. V.; Kniazev, A. Y.; Fabrika, S.; Sholukhova, O.; Berdnikov, L. N.; Cherepashchuk, A. M.; Zharova, A. V.

2010-06-01

We report the discovery of a new Galactic candidate luminous blue variable (cLBV) via detection of an infrared circular nebula and follow-up spectroscopy of its central star. The nebula, MN112, is one of many dozens of circular nebulae detected at 24μm in the Spitzer Space Telescope archival data, whose morphology is similar to that of nebulae associated with known (c)LBVs and related evolved massive stars. Specifically, the core-halo morphology of MN112 bears a striking resemblance to the circumstellar nebula associated with the Galactic cLBV GAL079.29+00.46, which suggests that both nebulae might have a similar origin and that the central star of MN112 is an LBV. The spectroscopy of the central star showed that its spectrum is almost identical to that of the bona fide LBV PCygni, which also supports the LBV classification of the object. To further constrain the nature of MN112, we searched for signatures of possible high-amplitude (>~1mag) photometric variability of the central star using archival and newly obtained photometric data covering a 45-yr period. We found that the B magnitude of the star was constant within error margins, while in the I band the star brightened by ~=0.4mag during the last 17 yr. Although the non-detection of large photometric variability leads us to use the prefix `candidate' in the classification of MN112, we remind the readers that the long-term photometric stability is not unusual for genuine LBVs and that the brightness of PCygni remained relatively stable during the last three centuries. Partially based on observations collected at the German-Spanish Astronomical Center, Calar Alto, jointly operated by the Max-Planck-Institut für Astronomie Heidelberg and the Instituto de Astrofísica de Andalucía (CSIC). E-mail: vgvaram@mx.iki.rssi.ru (VVG); akniazev@saao.ac.za (AYK); fabrika@sao.ru (SF); olga@sao.ru (OS); berdnik@sai.msu.ru (LNB); cher@sai.msu.ru (AMC); alla@sai.msu.ru (AVZ)

Candidate luminal B breast cancer genes identified by genome, gene expression and DNA methylation profiling.

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Stéphanie Cornen

Full Text Available Breast cancers (BCs of the luminal B subtype are estrogen receptor-positive (ER+, highly proliferative, resistant to standard therapies and have a poor prognosis. To better understand this subtype we compared DNA copy number aberrations (CNAs, DNA promoter methylation, gene expression profiles, and somatic mutations in nine selected genes, in 32 luminal B tumors with those observed in 156 BCs of the other molecular subtypes. Frequent CNAs included 8p11-p12 and 11q13.1-q13.2 amplifications, 7q11.22-q34, 8q21.12-q24.23, 12p12.3-p13.1, 12q13.11-q24.11, 14q21.1-q23.1, 17q11.1-q25.1, 20q11.23-q13.33 gains and 6q14.1-q24.2, 9p21.3-p24,3, 9q21.2, 18p11.31-p11.32 losses. A total of 237 and 101 luminal B-specific candidate oncogenes and tumor suppressor genes (TSGs presented a deregulated expression in relation with their CNAs, including 11 genes previously reported associated with endocrine resistance. Interestingly, 88% of the potential TSGs are located within chromosome arm 6q, and seven candidate oncogenes are potential therapeutic targets. A total of 100 candidate oncogenes were validated in a public series of 5,765 BCs and the overexpression of 67 of these was associated with poor survival in luminal tumors. Twenty-four genes presented a deregulated expression in relation with a high DNA methylation level. FOXO3, PIK3CA and TP53 were the most frequent mutated genes among the nine tested. In a meta-analysis of next-generation sequencing data in 875 BCs, KCNB2 mutations were associated with luminal B cases while candidate TSGs MDN1 (6q15 and UTRN (6q24, were mutated in this subtype. In conclusion, we have reported luminal B candidate genes that may play a role in the development and/or hormone resistance of this aggressive subtype.

THE ATACAMA COSMOLOGY TELESCOPE: ACT-CL J0102-4915 'EL GORDO', A MASSIVE MERGING CLUSTER AT REDSHIFT 0.87

Energy Technology Data Exchange (ETDEWEB)

Menanteau, Felipe; Hughes, John P.; Baker, Andrew J. [Department of Physics and Astronomy, Rutgers University, 136 Frelinghuysen Rd, Piscataway, NJ 08854 (United States); Sifon, Cristobal; Gonzalez, Jorge; Infante, Leopoldo; Felipe Barrientos, L. [Departamento de Astronomia y Astrofisica, Facultad de Fisica, Pontificia Universidad Catolica de Chile, Casilla 306, Santiago 22 (Chile); Hilton, Matt [School of Physics and Astronomy, University of Nottingham, University Park, Nottingham, NG7 2RD (United Kingdom); Bond, John R.; Hajian, Amir; Nolta, Michael R. [Canadian Institute for Theoretical Astrophysics, University of Toronto, Toronto, ON M5S 3H8 (Canada); Das, Sudeep [Berkeley Center for Cosmological Physics, LBL and Department of Physics, University of California, Berkeley, CA 94720 (United States); Devlin, Mark J.; Marsden, Danica [Department of Physics and Astronomy, University of Pennsylvania, 209 South 33rd Street, Philadelphia, PA 19104 (United States); Dunkley, Joanna [Department of Astrophysics, Oxford University, Oxford, OX1 3RH (United Kingdom); Hincks, Adam D. [Joseph Henry Laboratories of Physics, Jadwin Hall, Princeton University, Princeton, NJ 08544 (United States); Kosowsky, Arthur [Physics and Astronomy Department, University of Pittsburgh, 100 Allen Hall, 3941 O' Hara Street, Pittsburgh, PA 15260 (United States); Marriage, Tobias A. [Department of Physics and Astronomy, The Johns Hopkins University, Baltimore, MD 21218-2686 (United States); Moodley, Kavilan [Astrophysics and Cosmology Research Unit, School of Mathematical Sciences, University of KwaZulu-Natal, Durban 4041 (South Africa); Niemack, Michael D. [NIST Quantum Devices Group, 325 Broadway Mailcode 817.03, Boulder, CO 80305 (United States); and others

2012-03-20

We present a detailed analysis from new multi-wavelength observations of the exceptional galaxy cluster ACT-CL J0102-4915, likely the most massive, hottest, most X-ray luminous and brightest Sunyaev-Zel'dovich (SZ) effect cluster known at redshifts greater than 0.6. The Atacama Cosmology Telescope (ACT) collaboration discovered ACT-CL J0102-4915 as the most significant SZ decrement in a sky survey area of 755 deg{sup 2}. Our Very Large Telescope (VLT)/FORS2 spectra of 89 member galaxies yield a cluster redshift, z = 0.870, and velocity dispersion, {sigma}{sub gal} = 1321 {+-} 106 km s{sup -1}. Our Chandra observations reveal a hot and X-ray luminous system with an integrated temperature of T{sub X} = 14.5 {+-} 0.1 keV and 0.5-2.0 keV band luminosity of L{sub X} = (2.19 {+-} 0.11) Multiplication-Sign 10{sup 45} h{sup -2}{sub 70} erg s{sup -1}. We obtain several statistically consistent cluster mass estimates; using empirical mass scaling relations with velocity dispersion, X-ray Y{sub X}, and integrated SZ distortion, we estimate a cluster mass of M{sub 200a} = (2.16 {+-} 0.32) Multiplication-Sign 10{sup 15} h{sup -1}{sub 70} M{sub Sun }. We constrain the stellar content of the cluster to be less than 1% of the total mass, using Spitzer IRAC and optical imaging. The Chandra and VLT/FORS2 optical data also reveal that ACT-CL J0102-4915 is undergoing a major merger between components with a mass ratio of approximately 2 to 1. The X-ray data show significant temperature variations from a low of 6.6 {+-} 0.7 keV at the merging low-entropy, high-metallicity, cool core to a high of 22 {+-} 6 keV. We also see a wake in the X-ray surface brightness and deprojected gas density caused by the passage of one cluster through the other. Archival radio data at 843 MHz reveal diffuse radio emission that, if associated with the cluster, indicates the presence of an intense double radio relic, hosted by the highest redshift cluster yet. ACT-CL J0102-4915 is possibly a high

Prolonged photo-carriers generated in a massive-and-anisotropic Dirac material.

Science.gov (United States)

Nurmamat, Munisa; Ishida, Yukiaki; Yori, Ryohei; Sumida, Kazuki; Zhu, Siyuan; Nakatake, Masashi; Ueda, Yoshifumi; Taniguchi, Masaki; Shin, Shik; Akahama, Yuichi; Kimura, Akio

2018-06-13

Transient electron-hole pairs generated in semiconductors can exhibit unconventional excitonic condensation. Anisotropy in the carrier mass is considered as the key to elongate the life time of the pairs, and hence to stabilize the condensation. Here we employ time- and angle-resolved photoemission spectroscopy to explore the dynamics of photo-generated carriers in black phosphorus. The electronic structure above the Fermi level has been successfully observed, and a massive-and-anisotropic Dirac-type dispersions are confirmed; more importantly, we directly observe that the photo-carriers generated across the direct band gap have the life time exceeding 400 ps. Our finding confirms that black phosphorus is a suitable platform for excitonic condensations, and also open an avenue for future applications in broadband mid-infrared BP-based optoelectronic devices.

Massive neutrinos in astrophysics

International Nuclear Information System (INIS)

Qadir, A.

1982-08-01

Massive neutrinos are among the big hopes of cosmologists. If they happen to have the right mass they can close the Universe, explain the motion of galaxies in clusters, provide galactic halos and even, possibly, explain galaxy formation. Tremaine and Gunn have argued that massive neutrinos cannot do all these things. I will explain, here, what some of us believe is wrong with their arguments. (author)

Underlying mechanisms of transient luminous events: a review

OpenAIRE

V. V. Surkov; M. Hayakawa

2012-01-01

Transient luminous events (TLEs) occasionally observed above a strong thunderstorm system have been the subject of a great deal of research during recent years. The main goal of this review is to introduce readers to recent theories of electrodynamics processes associated with TLEs. We examine the simplest versions of these theories in order to make their physics as transparent as possible. The study is begun with the conventional mechanism for air breakdown at stratospheric...

Effects of feeding on luminal pH and morphology of the gastroesophageal junction of snakes.

Science.gov (United States)

Bessler, Scott M; Secor, Stephen M

2012-10-01

At the gastroesophageal junction, most vertebrates possess a functional lower esophageal sphincter (LES) which may serve to regulate the passage of liquids and food into the stomach and prevent the reflux of gastric contents into the esophagus. Snakes seemingly lack an LES and consume meals large enough to extend anteriorly from the stomach into the esophagus thereby providing the opportunity for the reflux of gastric juices. To explore whether snakes experience or can prevent gastric reflux, we examined post-feeding changes of luminal pH of the distal esophagus and stomach, the fine scale luminal pH profile at the gastroesophageal junction, and the morphology of the gastroesophageal junction for the Burmese python (Python molurus), the African brown house snake (Lamprophis fuliginosus), and the diamondback water snake (Nerodia rhombifer). For each species fasted, there was no distension of the gastroesophageal junction and only modest changes in luminal pH from the distal esophagus into the stomach. Feeding resulted in marked distension and changes in tissue morphology of the gastroesophageal junction. Simultaneously, there was a significant decrease in luminal pH of the distal esophagus for pythons and house snakes, and for all three species a steep gradient in luminal pH decreasing across a 3-cm span from the distal edge of the esophagus into the proximal edge of the stomach. The moderate acidification of the distal most portion of the esophagus for pythons and house snakes suggests that there is some anterior movement of gastric juices across the gastroesophageal junction. Given that this modest reflux of gastric fluid is localized to the most distal region of the esophagus, snakes are apparently able to prevent and protect against acid reflux in the absence of a functional LES. Copyright © 2012 Elsevier GmbH. All rights reserved.

Radiation properties of two types of luminous textile devices containing plastic optical fibers

Science.gov (United States)

Selm, Bärbel; Rothmaier, Markus

2007-05-01

Luminous textiles have the potential to satisfy a need for thin and flexible light diffusers for treatment of intraoral cancerous tissue. Plastic optical fibers (POF) with diameters of 250 microns and smaller are used to make the textiles luminous. Usually light is supplied to the optical fiber at both ends. On the textile surface light emission occurs in a woven structure via damaged straight POFs, whereas the embroidered structure radiates the light out of macroscopically bent POFs. We compared the optical properties of these two types of textile diffusers using red light laser for the embroidery and light emitting diode (LED) for the woven structure as light sources, and found efficiencies for the luminous areas of the two samples of 19 % (woven) and 32 % (embroidery), respectively. It was shown that the efficiency can be greatly improved using an aluminium backing. Additional scattering layers lower the fluence rate by around 30 %. To analyse the homogeneity we took a photo of the illuminated surface using a 3CCD camera and found, for both textiles, a slightly skewed distribution of the dark and bright pixels. The interquartile range of brightness distribution of the embroidery is more than double as the woven structure.

Clustering Batik Images using Fuzzy C-Means Algorithm Based on Log-Average Luminance

Directory of Open Access Journals (Sweden)

Ahmad Sanmorino

2012-06-01

Full Text Available Batik is a fabric or clothes that are made ​​with a special staining technique called wax-resist dyeing and is one of the cultural heritage which has high artistic value. In order to improve the efficiency and give better semantic to the image, some researchers apply clustering algorithm for managing images before they can be retrieved. Image clustering is a process of grouping images based on their similarity. In this paper we attempt to provide an alternative method of grouping batik image using fuzzy c-means (FCM algorithm based on log-average luminance of the batik. FCM clustering algorithm is an algorithm that works using fuzzy models that allow all data from all cluster members are formed with different degrees of membership between 0 and 1. Log-average luminance (LAL is the average value of the lighting in an image. We can compare different image lighting from one image to another using LAL. From the experiments that have been made, it can be concluded that fuzzy c-means algorithm can be used for batik image clustering based on log-average luminance of each image possessed.

Id-1 is not expressed in the luminal epithelial cells of mammary glands

International Nuclear Information System (INIS)

Uehara, Norihisa; Chou, Yu-Chien; Galvez, Jose J; Candia, Paola de; Cardiff, Robert D; Benezra, Robert; Shyamala, Gopalan

2003-01-01

The family of inhibitor of differentiation/DNA binding (Id) proteins is known to regulate development in several tissues. One member of this gene family, Id-1, has been implicated in mammary development and carcinogenesis. Mammary glands contain various cell types, among which the luminal epithelial cells are primarily targeted for proliferation, differentiation and carcinogenesis. Therefore, to assess the precise significance of Id-1 in mammary biology and carcinogenesis, we examined its cellular localization in vivo using immunohistochemistry. Extracts of whole mammary glands from wild type and Id-1 null mutant mice, and tissue sections from paraffin-embedded mouse mammary glands from various developmental stages and normal human breast were subjected to immunoblot and immunohistochemical analyses, respectively. In both these procedures, an anti-Id-1 rabbit polyclonal antibody was used for detection of Id-1. In immunoblot analyses, using whole mammary gland extracts, Id-1 was detected. In immunohistochemical analyses, however, Id-1 was not detected in the luminal epithelial cells of mammary glands during any stage of development, but it was detected in vascular endothelial cells. Id-1 is not expressed in the luminal epithelial cells of mammary glands

Increasing the luminous efficiency of an MEH-PPV based PLED using salmon DNA and single walled carbon nanotube

International Nuclear Information System (INIS)

Madhwal, Devinder; Singh, Inderpreet; Kumar, Jitender; Bhatia, C.S.; Bhatnagar, P.K.; Mathur, P.C.

2011-01-01

The combined effect of a salmon deoxyribonucleic acid (DNA)-based electron blocking layer and a single walled carbon nanotube (SWCNT) composite-based electron transport layer on the performance of a poly[2-methoxy-5-(2'-ethyl-hexyloxy)-1,4-phenylene vinylene] (MEH-PPV) polymer light emitting diode (PLED) has been examined. The SWCNT network in the composite layer improves electron injection from cathode and the DNA blocks these high mobility electrons at the electron blocking layer-polymer interface, leading to high luminance from the device. The luminous efficiency of the PLED is increased ∼20 times compared to that of a PLED using only MEH-PPV. - Highlights: → We report fabrication of a high luminous efficiency MEH-PPV based polymer LED. → Salmon DNA-CTMA layer is used to block injected electrons in the polymer layer. → MEH-PPV-SWCNT composite is used to transport electrons in the polymer layer. → The luminous efficiency of the polymer LED thereby improves about 20 times.

Enigmatic sub-luminous accreting neutron stars in our Galaxy

NARCIS (Netherlands)

Wijnands, R.

2008-01-01

During the last few years a class of enigmatic sub-luminous accreting neutron stars has been found in our Galaxy. They have peak X-ray luminosities (2-10 keV) of a few times 10(34) erg s(−1) to a few times 10(35) erg s(−1), and both persistent and transient sources have been found. I present a short

Automatic Supervision of Temperature, Humidity, and Luminance with an Assistant Personal Robot

Directory of Open Access Journals (Sweden)

Jordi Palacín

2017-01-01

Full Text Available Smart environments and Ambient Intelligence (AmI technologies are defining the future society where energy optimization and intelligent management are essential for a sustainable advance. Mobile robotics is also making an important contribution to this advance with the integration of sensors and intelligent processing algorithms. This paper presents the application of an Assistant Personal Robot (APR as an autonomous agent for temperature, humidity, and luminance supervision in human-frequented areas. The robot multiagent capabilities allow gathering sensor information while exploring or performing specific tasks and then verifying human comfortability levels. The proposed methodology creates information maps with the distribution of temperature, humidity, and luminance and interprets such information in terms of comfort and warns about corrective actuations if required.

A LUMINOUS, FAST RISING UV-TRANSIENT DISCOVERED BY ROTSE: A TIDAL DISRUPTION EVENT?

International Nuclear Information System (INIS)

Vinkó, J.; Wheeler, J. C.; Chatzopoulos, E.; Marion, G. H.; Yuan, F.; Akerlof, C.; Quimby, R. M.; Ramirez-Ruiz, E.; Guillochon, J.

2015-01-01

We present follow-up observations of an optical transient (OT) discovered by ROTSE on 2009 January 21. Photometric monitoring was carried out with ROTSE-IIIb in the optical and Swift in the UV up to +70 days after discovery. The light curve showed a fast rise time of ∼10 days followed by a steep decline over the next 60 days, which was much faster than that implied by 56 Ni— 56 Co radioactive decay. The Sloan Digital Sky Survey Data Release 10 database contains a faint, red object at the position of the OT, which appears slightly extended. This and other lines of evidence suggest that the OT is of extragalactic origin, and this faint object is likely the host galaxy. A sequence of optical spectra obtained with the 9.2 m Hobby-Eberly Telescope between +8 and +45 days after discovery revealed a hot, blue continuum with no visible spectral features. A few weak features that appeared after +30 days probably originated from the underlying host. Fitting synthetic templates to the observed spectrum of the host galaxy revealed a redshift of z = 0.19. At this redshift, the peak magnitude of the OT is close to –22.5, similar to the brightest super-luminous supernovae; however, the lack of identifiable spectral features makes the massive stellar death hypothesis less likely. A more plausible explanation appears to be the tidal disruption of a Sun-like star by the central supermassive black hole. We argue that this transient likely belongs to a class of super-Eddington tidal disruption events

Visceral Crisis Means Short Survival Among Patients With Luminal A Metastatic Breast Cancer: A Retrospective Cohort Study.

Science.gov (United States)

Sbitti, Yassir; Slimani, Khaoula; Debbagh, Adil; Mokhlis, Anouar; Kadiri, Habiba; Laraqui, Abdelilah; Errihani, Hassan; Ichou, Mohamed

2017-08-01

Patients with visceral crisis from luminal metastatic breast cancer (mBC) are often treated with palliative chemotherapy. No studies have analyzed the aggressiveness of the care in visceral crisis from luminal mBC patients. The objective of this study was to assess practices in this setting in a university medical oncology department. This retrospective study included all patients who were managed for luminal mBC between January 2013 and April 2016. The analysis focused on the characteristics of the patients, the modalities of cancer treatment and delays between visceral crisis and death. Thirty-five patients pre-treated with two hormonal therapy lines were enrolled retrospectively. Worse performance status and a higher proportion of severe organ dysfunction for luminal mBC were observed among patients with visceral crisis. Sixty-five percent of patients received cytotoxic treatment. One cycle of chemotherapy was administrated in the majority of patients. Palliative care was performed in 35% of patients. Chemotherapy did not have any significant effect on patient outcome in the present study. The mean time between visceral crisis and death was 4.7 weeks (standard deviation = 1.9). Our study showed that visceral crisis in patients with luminal mBC is a complex problem. We need more comprehension of molecular pathogenesis to visceral crisis disease to propose efficacious treatments for these patients and to identify subgroup of patients who need chemotherapy followed by maintenance endocrine therapy.

Curtain-Lifting Winds Allow Rare Glimpse into Massive Star Factory

Science.gov (United States)

2003-06-01

Formation of Exceedingly Luminous and Hot Stars in Young Stellar Cluster Observed Directly Summary Based on a vast observational effort with different telescopes and instruments, ESO-astronomer Dieter Nürnberger has obtained a first glimpse of the very first stages in the formation of heavy stars. These critical phases of stellar evolution are normally hidden from the view, because massive protostars are deeply embedded in their native clouds of dust and gas, impenetrable barriers to observations at all but the longest wavelengths. In particular, no visual or infrared observations have yet "caught" nascent heavy stars in the act and little is therefore known so far about the related processes. Profiting from the cloud-ripping effect of strong stellar winds from adjacent, hot stars in a young stellar cluster at the center of the NGC 3603 complex, several objects located near a giant molecular cloud were found to be bona-fide massive protostars, only about 100,000 years old and still growing. Three of these objects, designated IRS 9A-C, could be studied in more detail. They are very luminous (IRS 9A is about 100,000 times intrinsically brighter than the Sun), massive (more than 10 times the mass of the Sun) and hot (about 20,000 degrees). They are surrounded by relative cold dust (about 0°C), probably partly arranged in disks around these very young objects. Two possible scenarios for the formation of massive stars are currently proposed, by accretion of large amounts of circumstellar material or by collision (coalescence) of protostars of intermediate masses. The new observations favour accretion, i.e. the same process that is active during the formation of stars of smaller masses. PR Photo 16a/03: Stellar cluster and star-forming region NGC 3603. PR Photo 16b/03: Region near very young, massive stars IRS 9A-C in NGC 3603 (8 bands from J to Q). How do massive stars form? This question is easy to pose, but so far very difficult to answer. In fact, the processes

THE MOST MASSIVE ACTIVE BLACK HOLES AT z ∼ 1.5-3.5 HAVE HIGH SPINS AND RADIATIVE EFFICIENCIES

International Nuclear Information System (INIS)

Trakhtenbrot, Benny

2014-01-01

The radiative efficiencies (η) of 72 luminous unobscured active galactic nuclei at z ∼ 1.5-3.5, powered by some of the most massive black holes (BHs), are constrained. The analysis is based on accretion disk (AD) models, which link the continuum luminosity at rest-frame optical wavelengths and the BH mass (M BH ) to the accretion rate through the AD, M-dot AD . The data are gathered from several literature samples with detailed measurements of the Hβ emission line complex, observed at near-infrared bands. When coupled with standard estimates of bolometric luminosities (L bol ), the analysis suggests high radiative efficiencies, with most of the sources showing η > 0.2, that is, higher than the commonly assumed value of 0.1, and the expected value for non-spinning BHs (η = 0.057). Even under more conservative assumptions regarding L bol (i.e., L bol = 3 × L 5100 ), most of the extremely massive BHs in the sample (i.e., M BH ≳ 3 × 10 9 M ☉ ) show radiative efficiencies which correspond to very high BH spins (a * ), with typical values well above a * ≅ 0.7. These results stand in contrast to the predictions of a ''spin-down'' scenario, in which a series of randomly oriented accretion episodes leads to a * ∼ 0. Instead, the analysis presented here strongly supports a ''spin-up'' scenario, which is driven by either prolonged accretion or a series of anisotropically oriented accretion episodes. Considering the fact that these extreme BHs require long-duration or continuous accretion to account for their high masses, it is argued that the most probable scenario for the super-massive black holes under study is that of an almost continuous sequence of randomly yet not isotropically oriented accretion episodes

An Extreme Protocluster of Luminous Dusty Starbursts in the Early Universe

Science.gov (United States)

Oteo, I.; Ivison, R. J.; Dunne, L.; Manilla-Robles, A.; Maddox, S.; Lewis, A. J. R.; de Zotti, G.; Bremer, M.; Clements, D. L.; Cooray, A.; Dannerbauer, H.; Eales, S.; Greenslade, J.; Omont, A.; Perez–Fournón, I.; Riechers, D.; Scott, D.; van der Werf, P.; Weiss, A.; Zhang, Z.-Y.

2018-03-01

We report the identification of an extreme protocluster of galaxies in the early universe whose core (nicknamed Distant Red Core, DRC, because of its very red color in Herschel SPIRE bands) is formed by at least 10 dusty star-forming galaxies (DSFGs), spectroscopically confirmed to lie at {z}spec}=4.002 via detection of [C I](1–0), 12CO(6–5), 12CO(4–3), 12CO(2–1), and {{{H}}}2{{O}}({2}11{--}{2}02) emission lines with ALMA and ATCA. These DSFGs are distributed over a 260 {kpc}× 310 {kpc} region and have a collective obscured star formation rate (SFR) of ∼ 6500 {M}ȯ {yr}}-1, considerably higher than those seen before in any protocluster at z≳ 4. Most of the star formation is taking place in luminous DSFGs since no Lyα emitters are detected in the protocluster core, apart from a Lyα blob located next to one of the DRC components, extending over 60 {kpc}. The total obscured SFR of the protocluster could rise to {SFR}∼ {{14,400}} {M}ȯ {yr}}-1 if all the members of an overdensity of bright DSFGs discovered around DRC in a wide-field Large APEX BOlometer CAmera 870 μm image are part of the same structure. [C I](1–0) emission reveals that DRC has a total molecular gas mass of at least {M}{{{H}}2}∼ 6.6× {10}11 {M}ȯ , and its total halo mass could be as high as ∼ 4.4× {10}13 {M}ȯ , indicating that it is the likely progenitor of a cluster at least as massive as Coma at z = 0.

PAX2 is activated by estradiol in breast cancer cells of the luminal subgroup selectively, to confer a low invasive phenotype

Science.gov (United States)

2011-01-01

Background Metastasis is the leading cause of death among breast cancer patients. Identifying key cellular factors controlling invasion and metastasis of breast cancer cells should pave the way to new therapeutic strategies efficiently interfering with the metastatic process. PAX2 (paired box 2) transcription factor is expressed by breast cancer cells in vivo and recently, it was shown to negatively regulate the expression of ERBB2 (erythroblastic leukemia viral oncogene homolog 2, HER-2/neu), a well-documented pro-invasive and pro-metastastic gene, in luminal/ERalpha-positive (ERα+) breast cancer cells. The objective of the present study was to investigate a putative role for PAX2 in the control of luminal breast cancer cells invasion, and to begin to characterize its regulation. Results PAX2 activity was higher in cell lines from luminal compared to non-luminal subtype, and activation of PAX2 by estradiol was selectively achieved in breast cancer cell lines of the luminal subtype. This process was blocked by ICI 182780 and could be antagonized by IGF-1. Knockdown of PAX2 in luminal MCF-7 cells completely abrogated estradiol-induced downregulation of ERBB2 and decrease of cell invasion, whereas overexpression of PAX2 in these cells enhanced estradiol effects on ERBB2 levels and cell invasion. Conclusions The study demonstrates that PAX2 activation by estradiol is selectively achieved in breast cancer cells of the luminal subtype, via ERα, and identifies IGF-1 as a negative regulator of PAX2 activity in these cells. Further, it reveals a new role for PAX2 in the maintenance of a low invasive behavior in luminal breast cancer cells upon exposure to estradiol, and shows that overexpression and activation of PAX2 in these cells is sufficient to reduce their invasive ability. PMID:22168360

Inhibitors of acid secretion can benefit gastric wound repair independent of luminal pH effects on the site of damage

Science.gov (United States)

Demitrack, Elise S; Aihara, Eitaro; Kenny, Susan; Varro, Andrea; Montrose, Marshall H

2012-01-01

Background and aims The authors’ goal was to measure pH at the gastric surface (pHo) to understand how acid secretion affects the repair of microscopic injury to the gastric epithelium. Methods Microscopic gastric damage was induced by laser light, during confocal/two-photon imaging of pH-sensitive dyes (Cl-NERF, BCECF) that were superfused over the mucosal surface of the exposed gastric corpus of anaesthetised mice. The progression of repair was measured in parallel with pHo. Experimental conditions included varying pH of luminal superfusates, and using omeprazole (60 mg/kg ip) or famotidine (30 mg/kg ip) to inhibit acid secretion. Results Similar rates of epithelial repair and resting pHo values (~pH 4) were reported in the presence of luminal pH 3 or pH 5. Epithelial repair was unreliable at luminal pH 2 and pHo was lower (2.5±0.2, P pH 3). Epithelial repair was slower at luminal pH 7 and pHo was higher (6.4±0.1, PpH 3 or pH 7, omeprazole reduced maximal damage size and accelerated epithelial repair, although only at pH 3 did omeprazole further increase surface pH above the level caused by imposed damage. At luminal pH 7, famotidine also reduced maximal damage size and accelerated epithelial repair. Neither famotidine nor omeprazole raised plasma gastrin levels during the time course of the experiments. Conclusions Epithelial repair in vivo is affected by luminal pH variation, but the beneficial effects of acutely blocking acid secretion extend beyond simply raising luminal and/or surface pH. PMID:21997560

SI 1985 No. 1048 - The Radioactive Substances (Luminous Articles) Exemption Order 1985

International Nuclear Information System (INIS)

1985-01-01

This Order, which came into force on 17 September 1985, is concerned with exemptions and exclusions under the Radioactive Substances Act 1960 in respect of radioactive luminous instruments and indicators. (NEA) [fr

Luminal digestion of lactoferrin in suckling and weanling rats

International Nuclear Information System (INIS)

Britton, J.R.; Koldovsky, O.

1987-01-01

The development of luminal digestion of lactoferrin was evaluated in vitro by incubating 125 I-labeled lactoferrin with fluid flushed from the stomach and small intestine of 12-day-old suckling and 31-day-old weanling rats, followed by measurement of radioactivity in trichloroacetic acid-soluble material. Gastric hydrolysis of lactoferrin at pH 3.2 in the weanling was 20-fold greater than that in the suckling. In the small intestine at neutral pH, luminal degradation of lactoferrin was minimal in the suckling but increased significantly after weaning, with maximal degradative capacity demonstrable in the midjejunum. Sephadex G-75 chromatography of intestinal acid-soluble breakdown products revealed two peaks of radioactivity, each comprising 40-45% of the total product; analysis of intestinal acid-precipitable products by polyacrylamide gel electrophoresis yielded several discrete lower molecular weight species. Food deprivation for 12 h/100 g body wt decreased lactoferrin degradation in the weanling jejunum and midjejunum. The findings suggest that lactoferrin digestion may vary with respect to postnatal age of the organism, segment of the gastrointestinal tract, and dietary state. In the young animal, lactoferrin degradation is minimal, and consequently its potential for biological function may be high

The efficiency of seismic attributes to differentiate between massive and non-massive carbonate successions for hydrocarbon exploration activity

Science.gov (United States)

Sarhan, Mohammad Abdelfattah

2017-12-01

The present work investigates the efficiency of applying volume seismic attributes to differentiate between massive and non-massive carbonate sedimentary successions on using seismic data. The main objective of this work is to provide a pre-drilling technique to recognize the porous carbonate section (probable hydrocarbon reservoirs) based on seismic data. A case study from the Upper Cretaceous - Eocene carbonate successions of Abu Gharadig Basin, northern Western Desert of Egypt has been tested in this work. The qualitative interpretations of the well-log data of four available wells distributed in the study area, namely; AG-2, AG-5, AG-6 and AG-15 wells, has confirmed that the Upper Cretaceous Khoman A Member represents the massive carbonate section whereas the Eocene Apollonia Formation represents the non-massive carbonate unit. The present work have proved that the most promising seismic attributes capable of differentiating between massive and non-massive carbonate sequences are; Root Mean Square (RMS) Amplitude, Envelope (Reflection Strength), Instantaneous Frequency, Chaos, Local Flatness and Relative Acoustic Impedance.

Gastric luminal epidermal growth factor is affected by diet | Iputo ...

African Journals Online (AJOL)

Objective. Diet is an area of major interest to those investigating the causes of cancer of the oesophagus in the Transkei. This study looked at the associations between intragastric epidermal growth factor level, diet and intragastric pH. Setting and subjects. A dietary survey was co-ordinated with studies of gastric luminal ...

The predetermination of the luminance in tunnel entrances at day.

NARCIS (Netherlands)

Schreuder, D.A. & Oud, H.J.C.

1988-01-01

In tunnel lighting practice, only the scatter in the eye, in the windscreen of the car, and in the atmosphere need to be taken into account. For all practical day- time conditions, the required luminance in any portion of the tunnel can be assessed as being a constant fraction of this sum-

Decay time shortening of fluorescence from donor-acceptor pair proteins using ultrafast time-resolved fluorescence resonance energy transfer spectroscopy

International Nuclear Information System (INIS)

Baba, Motoyoshi; Suzuki, Masayuki; Ganeev, Rashid A.; Kuroda, Hiroto; Ozaki, Tsuneyuki; Hamakubo, Takao; Masuda, Kazuyuki; Hayashi, Masahiro; Sakihama, Toshiko; Kodama, Tatsuhiko; Kozasa, Tohru

2007-01-01

We improved an ultrafast time-resolved fluorescence resonance energy transfer (FRET) spectroscopy system and measured directly the decrease in the fluorescence decay time of the FRET signal, without any entanglement of components in the picosecond time scale from the donor-acceptor protein pairs (such as cameleon protein for calcium ion indicator, and ligand-activated GRIN-Go proteins pair). The drastic decrease in lifetime of the donor protein fluorescence under the FRET condition (e.g. a 47.8% decrease for a GRIN-Go protein pair) proves the deformation dynamics between donor and acceptor fluorescent proteins in an activated state of a mixed donor-acceptor protein pair. This study is the first clear evidence of physical contact of the GRIN-Go proteins pair using time-resolved FRET system. G protein-coupled receptors (GPCRs) are the most important protein family for the recognition of many chemical substances at the cell surface. They are the targets of many drugs. Simultaneously, we were able to observe the time-resolved spectra of luminous proteins at the initial stage under the FRET condition, within 10 ns from excitation. This new FRET system allows us to trace the dynamics of the interaction between proteins at the ligand-induced activated state, molecular structure change and combination or dissociation. It will be a key technology for the development of protein chip technology

SPITZER MICROLENS MEASUREMENT OF A MASSIVE REMNANT IN A WELL-SEPARATED BINARY

Energy Technology Data Exchange (ETDEWEB)

Shvartzvald, Y.; Bryden, G.; Henderson, C. B. [Jet Propulsion Laboratory, California Institute of Technology, 4800 Oak Grove Drive, Pasadena, CA 91109 (United States); Udalski, A. [Warsaw University Observatory, Al. Ujazdowskie 4, 00-478 Warszawa (Poland); Gould, A.; Fausnaugh, M.; Gaudi, B. S.; Pogge, R. W.; Wibking, B.; Zhu, W. [Department of Astronomy, Ohio State University, 140 W. 18th Avenue, Columbus, OH 43210 (United States); Han, C. [Department of Physics, Chungbuk National University, Cheongju 361-763 (Korea, Republic of); Bozza, V.; Novati, S. Calchi [Dipartimento di Fisica “E. R. Caianiello,” Università di Salerno, Via Giovanni Paolo II, I-84084 Fisciano (Italy); Friedmann, M. [School of Physics and Astronomy, Tel-Aviv University, Tel-Aviv 69978 (Israel); Hundertmark, M. [Niels Bohr Institute and Centre for Star and Planet Formation, University of Copenhagen, Øster Voldgade 5, DK-1350 Copenhagen K (Denmark); Beichman, C. [NASA Exoplanet Science Institute, MS 100-22, California Institute of Technology, Pasadena, CA 91125 (United States); Carey, S. [Spitzer, Science Center, MS 220-6, California Institute of Technology, Pasadena, CA (United States); Kerr, T.; Varricatt, W. [UKIRT, 660 N. Aohoku Place, University Park, Hilo, HI 96720 (United States); Yee, J. C. [Harvard-Smithsonian Center for Astrophysics, 60 Garden Street, Cambridge, MA 02138 (United States); Collaboration: and; Spitzer team; OGLE group; KMTNet group; Wise group; RoboNet; MiNDSTEp; and others

2015-12-01

We report the detection and mass measurement of a binary lens OGLE-2015-BLG-1285La,b, with the more massive component having M{sub 1} > 1.35 M{sub ⊙} (80% probability). A main-sequence star in this mass range is ruled out by limits on blue light, meaning that a primary in this mass range must be a neutron star (NS) or black hole (BH). The system has a projected separation r{sub ⊥} = 6.1 ± 0.4 AU and lies in the Galactic bulge. These measurements are based on the “microlens parallax” effect, i.e., comparing the microlensing light curve as seen from Spitzer, which lay at 1.25 AU projected from Earth, to the light curves from four ground-based surveys, three in the optical and one in the near-infrared. Future adaptive optics imaging of the companion by 30 m class telescopes will yield a much more accurate measurement of the primary mass. This discovery both opens the path and defines the challenges to detecting and characterizing BHs and NSs in wide binaries, with either dark or luminous companions. In particular, we discuss lessons that can be applied to future Spitzer and Kepler K2 microlensing parallax observations.

Immunoelectron microscopic localisation of keratin and luminal epithelial antigens in normal and neoplastic urothelium.

Science.gov (United States)

Wilson, P D; Nathrath, W B; Trejdosiewicz, L K

1982-01-01

Immunoelectron microscope cytochemistry was carried out on 2% paraformaldehyde fixed, 50 mu sections of normal urothelium and bladder carcinoma cells in culture using antisera raised in rabbits to human 40-63 000 MW epidermal "broad spectrum" keratin and calf urothelial "luminal epithelial antigen" (aLEA) Both the unconjugated and indirect immunoperoxidase-DAB techniques were used before routine embedding. The localisation of both keratin and luminal epithelial antigen (LEA) was similar in normal and neoplastic cells and reaction product was associated not only with tonofilaments but also lining membrane vesicles and on fine filaments in the cytoplasmic ground substance.

Massive Born--Infeld and Other Dual Pairs

CERN Document Server

Ferrara, S

2015-01-01

We consider massive dual pairs of p-forms and (D-p-1)-forms described by non-linear Lagrangians, where non-linear curvature terms in one theory translate into non-linear mass-like terms in the dual theory. In particular, for D=2p and p even the two non-linear structures coincide when the non-linear massless theory is self-dual. This state of affairs finds a natural realization in the four-dimensional massive N=1 supersymmetric Born-Infeld action, which describes either a massive vector multiplet or a massive linear (tensor) multiplet with a Born-Infeld mass-like term. These systems should play a role for the massive gravitino multiplet obtained from a partial super-Higgs in N=2 Supergravity.

Assessment of atherosclerotic luminal narrowing of coronary arteries based on morphometrically generated visual guides.

Science.gov (United States)

Barth, Rolf F; Kellough, David A; Allenby, Patricia; Blower, Luke E; Hammond, Scott H; Allenby, Greg M; Buja, L Maximilian

Determination of the degree of stenosis of atherosclerotic coronary arteries is an important part of postmortem examination of the heart, but, unfortunately, estimation of the degree of luminal narrowing can be imprecise and tends to be approximations. Visual guides can be useful to assess this, but earlier attempts to develop such guides did not employ digital technology. Using this approach, we have developed two computer-generated morphometric guides to estimate the degree of luminal narrowing of atherosclerotic coronary arteries. The first is based on symmetric or eccentric circular or crescentic narrowing of the vessel lumen and the second on either slit-like or irregularly shaped narrowing of the vessel lumens. Using the Aperio ScanScope XT at a magnification of 20× we created digital whole-slide images of 20 representative microscopic cross sections of the left anterior descending (LAD) coronary artery, stained with either hematoxylin and eosin (H&E) or Movat's pentachrome stain. These cross sections illustrated a variety of luminal profiles and degrees of stenosis. Three representative types of images were selected and a visual guide was constructed with Adobe Photoshop CS5. Using the "Scale" and "Measurement" tools, we created a series of representations of stenosis with luminal cross sections depicting 20%, 40%, 60%, 70%, 80%, and 90% occlusion of the LAD branch. Four pathologists independently reviewed and scored the degree of atherosclerotic luminal narrowing based on our visual guides. In addition, digital technology was employed to determine the degree of narrowing by measuring the cross-sectional area of the 20 microscopic sections of the vessels, first assuming no narrowing and then comparing this to the percent of narrowing determined by precise measurement. Two of the observers were very experienced general autopsy pathologists, one was a first-year pathology resident on his first rotation on the autopsy service, and the fourth observer was a

Spatially-resolved star formation histories of CALIFA galaxies. Implications for galaxy formation

Science.gov (United States)

González Delgado, R. M.; Pérez, E.; Cid Fernandes, R.; García-Benito, R.; López Fernández, R.; Vale Asari, N.; Cortijo-Ferrero, C.; de Amorim, A. L.; Lacerda, E. A. D.; Sánchez, S. F.; Lehnert, M. D.; Walcher, C. J.

2017-11-01

This paper presents the spatially resolved star formation history (SFH) of nearby galaxies with the aim of furthering our understanding of the different processes involved in the formation and evolution of galaxies. To this end, we apply the fossil record method of stellar population synthesis to a rich and diverse data set of 436 galaxies observed with integral field spectroscopy in the CALIFA survey. The sample covers a wide range of Hubble types, with stellar masses ranging from M⋆ 109 to 7 × 1011 M⊙. Spectral synthesis techniques are applied to the datacubes to retrieve the spatially resolved time evolution of the star formation rate (SFR), its intensity (ΣSFR), and other descriptors of the 2D SFH in seven bins of galaxy morphology (E, S0, Sa, Sb, Sbc, Sc, and Sd) and five bins of stellar mass. Our main results are that (a) galaxies form very fast independently of their current stellar mass, with the peak of star formation at high redshift (z > 2). Subsequent star formation is driven by M⋆ and morphology, with less massive and later type spirals showing more prolonged periods of star formation. (b) At any epoch in the past, the SFR is proportional to M⋆, with most massive galaxies having the highest absolute (but lowest specific) SFRs. (c) While today, the ΣSFR is similar for all spirals and significantly lower in early-type galaxies (ETG), in the past, the ΣSFR scales well with morphology. The central regions of today's ETGs are where the ΣSFR reached the highest values (> 103 M⊙ Gyr-1 pc-2), similar to those measured in high-redshift star-forming galaxies. (d) The evolution of ΣSFR in Sbc systems matches that of models for Milky Way-like galaxies, suggesting that the formation of a thick disk may be a common phase in spirals at early epochs. (e) The SFR and ΣSFR in outer regions of E and S0 galaxies show that they have undergone an extended phase of growth in mass between z = 2 and 0.4. The mass assembled in this phase is in agreement with

MASSIVE+: The Growth Histories of MASSIVE Survey Galaxies from their Globular Cluster Colors

Science.gov (United States)

Blakeslee, John

2017-08-01

The MASSIVE survey is targeting the 100 most massive galaxies within 108 Mpc that are visible in the northern sky. These most massive galaxies in the present-day universe reside in a surprisingly wide variety of environments, from rich clusters to fossil groups to near isolation. We propose to use WFC3/UVIS and ACS to carry out a deep imaging study of the globular cluster populations around a selected subset of the MASSIVE targets. Though much is known about GC systems of bright galaxies in rich clusters, we know surprisingly little about the effects of environment on these systems. The MASSIVE sample provides a golden opportunity to learn about the systematics of GC systems and what they can tell us about environmental drivers on the evolution of the highest mass galaxies. The most pressing questions to be addressed include: (1) Do isolated giants have the same constant mass fraction of GCs to total halo mass as BCGs of similar luminosity? (2) Do their GC systems show the same color (metallicity) distribution, which is an outcome of the mass spectrum of gas-rich halos during hierarchical growth? (3) Do the GCs in isolated high-mass galaxies follow the same radial distribution versus metallicity as in rich environments (a test of the relative importance of growth by accretion)? (4) Do the GCs of galaxies in sparse environments follow the same mass function? Our proposed second-band imaging will enable us to secure answers to these questions and add enormously to the legacy value of existing HST imaging of the highest mass galaxies in the universe.

Sn-doped polyhedral In2O3 particles: Synthesis, characterization, and origins of luminous emission in wide visible range

International Nuclear Information System (INIS)

Zhu Yunqing; Chen Yiqing

2012-01-01

Sn-doped octahedronal and tetrakaidecahedronal In 2 O 3 particles were successfully synthesized by simple thermal evaporation of indium grains using SnO as dopant. Structural characterization results demonstrated that the Sn-doped tetrakaidecahedronal In 2 O 3 particle had additional six {001} crystal surfaces compared with the octahedronal one. The luminous properties of both samples were characterized by photoluminescence (PL) and cathodoluminescence (CL) spectroscopy. A broad visible luminous emission around 570 nm was observed. Studies revealed that the emission consisted of three peaks of 511 nm, 564 nm, and 622 nm, which were attributed to radioactive recombination centers such as single ionized oxygen vacancy, indium interstitial, and antisite oxygen, respectively. We believe that the Sn donor level plays an important role in the visible luminous emission. - Graphical abstract: With more oxygen vacancies and tin doping. ITO particles can exhibit a better CL performance. Sn donor level near the conduction band edge plays an important role in luminous emission in wide visible range. Highlights: ► Polyhedral ITO particles synthesized by thermal evaporation using SnO as dopant. ► Broad visible luminous emission around 570 nm. ► Sn donor level plays an important role in the visible emission. ► ITO particles with more oxygen vacancies have better CL performance in visible range.

Endoscopic visualization of luminal organ and great vessels with three dimensional CT scanner

International Nuclear Information System (INIS)

Kobayashi, Hisashi; Okumura, Toshiyuki; Amemiya, Ryuta; Hasegawa, Hiroshi

1992-01-01

Thirty cases examined by three dimensional CT scanner (3DCT) are reported. The observation of inner view using 3DCT were performed in 12 large vessels with vascular disorder, 10 pulmonary bronchi with lung cancer and 8 common bile ducts involved obstructive disease. In order to visualize interface of the lumen, a new software, which was developed by HITACHI MEDICO Inc., was used. In all cases but one the inner view of the luminal organ was clearly demonstrated as 3D images and it was possible to judge some changes of luminal interface involved by the diseases. The 3DCT endoscopic image might be useful as a new endoscopic technique without fiberscopy. (author)

Increased luminance of MEH-PPV and PFO based PLEDs by using salmon DNA as an electron blocking layer

International Nuclear Information System (INIS)

Madhwal, Devinder; Rait, S.S.; Verma, A.; Kumar, Amit; Bhatnagar, P.K.; Mathur, P.C.; Onoda, M.

2010-01-01

The effect of salmon DNA-CTMA as an electron blocking layer (EBL) has been examined on the performance of MEH-PPV and PFO-based light emitting diodes. Though the turn-on voltage increases with incorporation of EBL, a significant increase in luminance and luminous efficiency for both the devices is observed. The EBL improves the device performance by blocking electrons at the EBL-polymer interface, thereby increasing the recombination probability of electrons and holes. The luminance of the MEH-PPV based Bio-LED increases to 100 cd/m 2 from 30 cd/m 2 while a corresponding increase for the PFO based LED is to 160 cd/m 2 from 80 cd/m 2 with and without EBL, respectively.

Symbiotic association of Photobacterium fischeri with the marine luminous fish Monocentris japonica; a model of symbiosis based on bacterial studies.

Science.gov (United States)

Ruby, E G; Nealson, K H

1976-12-01

Isolation of bacteria from the luminous organ of the fish Monocentris japonica has revealed that the organ contains a pure culture of luminous bacteria. For the four fish examined, all contained Photobacterium fischeri as their luminous bacterial symbiont. This is the first time that P. fischeri has been identified in a symbiotic association. A representative isolate (MJl) of the light organ population was selected for in vivo studies of its luminous system. Several physiological features suggest adaptation for symbiotic existence. First, MJl has been shown to produce and respond to an inducer of luciferase that could accumulate in the light organ. Secondly, the specific activity of light production was seen to be maximal under low, growth-limiting concentrations of oxygen. Thirdly, unlike another luminous species (Beneckea harveyi), synthesis of the light production system of these bacteria is not catabolite repressed by glucose--a possible source of nutrition in the light organ. Fourthly, when grown aerobically on glucose these bacteria excrete pyruvic acid into the medium. This production of pyruvate is a major process, accounting for 30-40% of the glucose utilized and may serve as a form of regulatory and nutritional communication with the host.

Luminance and image quality analysis of an organic electroluminescent panel with a patterned microlens array attachment

International Nuclear Information System (INIS)

Lin, Hoang Yan; Chen, Kuan-Yu; Ho, Yu-Hsuan; Fang, Jheng-Hao; Hsu, Sheng-Chih; Lee, Jiun-Haw; Lin, Jia-Rong; Wei, Mao-Kuo

2010-01-01

Luminance and image quality observed from the normal direction of a commercial 2.0 inch panel based on organic electroluminescence (OEL) technology attached to regular and patterned microlens array films (MAFs) were studied and analyzed. When applying the regularly arranged MAF on the panel, a luminance enhancement of 23% was observed, accompanied by a reduction of the image quality index as low as 74%. By removing the microlenses on the emitting areas, the patterned MAF enhances the luminance efficiency of the OEL by 52% keeping the image quality index of the display as high as 94%, due to the effective light extraction in the glass substrate being less than the critical angle. 3D simulation based on a ray-tracing model was also established to investigate the spatial distribution of light rays radiated from an OEL pixel with different microstructures which showed consistent results with the experimental results

Omission of Breast Radiotherapy in Low-risk Luminal A Breast Cancer: Impact on Health Care Costs.

Science.gov (United States)

Han, K; Yap, M L; Yong, J H E; Mittmann, N; Hoch, J S; Fyles, A W; Warde, P; Gutierrez, E; Lymberiou, T; Foxcroft, S; Liu, F F

2016-09-01

The economic burden of cancer care is substantial, including steep increases in costs for breast cancer management. There is mounting evidence that women age ≥ 60 years with grade I/II T1N0 luminal A (ER/PR+, HER2- and Ki67 ≤ 13%) breast cancer have such low local recurrence rates that adjuvant breast radiotherapy might offer limited value. We aimed to determine the total savings to a publicly funded health care system should omission of radiotherapy become standard of care for these patients. The number of women aged ≥ 60 years who received adjuvant radiotherapy for T1N0 ER+ HER2- breast cancer in Ontario was obtained from the provincial cancer agency. The cost of adjuvant breast radiotherapy was estimated through activity-based costing from a public payer perspective. The total saving was calculated by multiplying the estimated number of luminal A cases that received radiotherapy by the cost of radiotherapy minus Ki-67 testing. In 2010, 748 women age ≥ 60 years underwent surgery for pT1N0 ER+ HER2- breast cancer; 539 (72%) underwent adjuvant radiotherapy, of whom 329 were estimated to be grade I/II luminal A subtype. The cost of adjuvant breast radiotherapy per case was estimated at $6135.85; the cost of Ki-67 at $114.71. This translated into an annual saving of about $2.0million if radiotherapy was omitted for all low-risk luminal A breast cancer patients in Ontario and $5.1million across Canada. There will be significant savings to the health care system should omission of radiotherapy become standard practice for women with low-risk luminal A breast cancer. Copyright © 2016 The Royal College of Radiologists. Published by Elsevier Ltd. All rights reserved.

Unilateral post-tuberculosis lung destruction and massive haemoptysis in pregnancy with successful outcome

Directory of Open Access Journals (Sweden)

Abiodun S. Adeniran

2016-06-01

We present an unbooked 36 year old G6P4+1 (4 alive woman who presented with chronic cough, massive haemoptysis and multiple pregnancy (twin at 35 week gestation. She had completed anti-tuberculosis treatment twice at and over nine years prior to presentation. On evaluation, there were clinical and radiological evidences of unilateral (right destroyed lung but no evidence of active tuberculosis; resuscitation was with antibiotics, blood transfusion and oxygen therapy followed by an emergency caesarean delivery due to significant maternal compromise. The symptoms resolved following antibiotic therapy and she was subsequently discharged home. Post-tuberculosis destroyed lung is a fatal uncommon condition that may present during pregnancy and requires a multi-disciplinary specialist care to ensure good maternal and foetal outcome.

Detecting Massive, High-Redshift Galaxy Clusters Using the Thermal Sunyaev-Zel'dovich Effect

Science.gov (United States)

Adams, Carson; Steinhardt, Charles L.; Loeb, Abraham; Karim, Alexander; Staguhn, Johannes; Erler, Jens; Capak, Peter L.

2017-01-01

We develop the thermal Sunyaev-Zel'dovich (SZ) effect as a direct astrophysical measure of the mass distribution of dark matter halos. The SZ effect increases with cosmological distance, a unique astronomical property, and is highly sensitive to halo mass. We find that this presents a powerful methodology for distinguishing between competing models of the halo mass function distribution, particularly in the high-redshift domain just a few hundred million years after the Big Bang. Recent surveys designed to probe this epoch of initial galaxy formation such as CANDELS and SPLASH report an over-abundance of highly massive halos as inferred from stellar ultraviolet (UV) luminosities and the stellar mass to halo mass ratio estimated from nearby galaxies. If these UV luminosity to halo mass relations hold to high-redshift, observations estimate several orders of magnitude more highly massive halos than predicted by hierarchical merging and the standard cosmological paradigm. Strong constraints on the masses of these galaxy clusters are essential to resolving the current tension between observation and theory. We conclude that detections of thermal SZ sources are plausible at high-redshift only for the halo masses inferred from observation. Therefore, future SZ surveys will provide a robust determination between theoretical and observational predictions.

Thermodynamics inducing massive particles' tunneling and cosmic censorship

International Nuclear Information System (INIS)

Zhang, Baocheng; Cai, Qing-yu; Zhan, Ming-sheng

2010-01-01

By calculating the change of entropy, we prove that the first law of black hole thermodynamics leads to the tunneling probability of massive particles through the horizon, including the tunneling probability of massive charged particles from the Reissner-Nordstroem black hole and the Kerr-Newman black hole. Novelly, we find the trajectories of massive particles are close to that of massless particles near the horizon, although the trajectories of massive charged particles may be affected by electromagnetic forces. We show that Hawking radiation as massive particles tunneling does not lead to violation of the weak cosmic-censorship conjecture. (orig.)

Intratumoral estrogen production and actions in luminal A type invasive lobular and ductal carcinomas.

Science.gov (United States)

Takagi, Mayu; Miki, Yasuhiro; Miyashita, Minoru; Hata, Shuko; Yoda, Tomomi; Hirakawa, Hisashi; Sagara, Yasuaki; Rai, Yoshiaki; Ohi, Yasuyo; Tamaki, Kentaro; Ishida, Takanori; Suzuki, Takashi; Ouchi, Noriaki; Sasano, Hironobu

2016-02-01

The great majority of invasive lobular carcinoma (ILC) is estrogen-dependent luminal A type carcinoma but the details of estrogen actions and its intratumoral metabolism have not been well studied compared to invasive ductal carcinoma (IDC). We first immunolocalized estrogen-related enzymes including estrogen sulfotransferase (EST), estrogen sulfatase (STS), 17β-hydroxysteroid dehydrogenase (HSD) 1/2, and aromatase. We then evaluated the tissue concentrations of estrogens in ILC and IDC and subsequently estrogen-responsive gene profiles in these tumors in order to explore the possible differences and/or similarity of intratumoral estrogen environment of these two breast cancer subtypes. The status of STS and 17βHSD1 was significantly lower in ILCs than IDCs (p = 0.022 and p < 0.0001), but that of EST and 17βHSD2 vice versa (p < 0.0001 and p = 0.0106). In ILCs, tissue concentrations of estrone and estradiol were lower than those in IDCs (p = 0.0709 and 0.069). In addition, the great majority of estrogen response genes tended to be lower in ILCs. Among those genes above, FOXP1 was significantly higher in ILCs than in IDCs (p = 0.002). FOXP1 expression was reported to be significantly higher in relapse-free IDC patients treated with tamoxifen. Therefore, tamoxifen may be considered an option of endocrine therapy for luminal A type ILC patients. This is the first study to demonstrate the detailed and comprehensive status of intratumoral production and metabolism of estrogens and the status of estrogen response genes in luminal A-like ILC with comparison to those in luminal A-like IDCs.

Topological massive sigma models

International Nuclear Information System (INIS)

Lambert, N.D.

1995-01-01

In this paper we construct topological sigma models which include a potential and are related to twisted massive supersymmetric sigma models. Contrary to a previous construction these models have no central charge and do not require the manifold to admit a Killing vector. We use the topological massive sigma model constructed here to simplify the calculation of the observables. Lastly it is noted that this model can be viewed as interpolating between topological massless sigma models and topological Landau-Ginzburg models. ((orig.))

RESOLVED DUST EMISSION IN A QUASAR AT z = 3.65

International Nuclear Information System (INIS)

Clements, D. L.; Babbedge, T.; Rowan-Robinson, M.; Petitpas, G.; Farrah, D.; Hatziminaoglou, E.; Perez-Fournon, I.; Hernan-Caballero, Antonio; Castro-RodrIguez, Nieves; Lonsdale, C.; Surace, J.; Franceschini, A.; Wilkes, B. J.; Smith, H.

2009-01-01

We present submillimeter observations of the z= 3.653 quasar SDSS 160705+533558 together with data in the optical and infrared. The object is unusually bright in the far-IR and submillimeter with an IR luminosity of ∼10 14 L sun . We ascribe this luminosity to a combination of active galactic nucleus (AGN) and starburst emission, with the starburst forming stars at a rate of a few thousand solar masses per year. Submillimeter Array imaging observations with a resolution ∼1'' show that the submillimeter (850 μm) emission is extended on scales of 10- 35 kpc and is offset from the optical position by ∼10 kpc. This morphology is dissimilar to that found in submillimeter galaxies, which are generally unresolved or marginally resolved on arcsecond scales, or submillimeter-luminous AGNs where the AGN lies at the peak of the submillimeter or molecular emission. The simplest explanation is that the object is in the early stages of a merger between a gas-rich galaxy, which hosts the starburst, and a gas-poor AGN-host galaxy, which is responsible for the quasar emission. It is also possible that jet-induced star formation might contribute to the unusual morphology.

Effect of low-dose ionizing radiation on luminous marine bacteria: radiation hormesis and toxicity

International Nuclear Information System (INIS)

Kudryasheva, N.S.; Rozhko, T.V.

2015-01-01

The paper summarizes studies of effects of alpha- and beta-emitting radionuclides (americium-241, uranium-235+238, and tritium) on marine microorganisms under conditions of chronic low-dose irradiation in aqueous media. Luminous marine bacteria were chosen as an example of these microorganisms; bioluminescent intensity was used as a tested physiological parameter. Non-linear dose-effect dependence was demonstrated. Three successive stages in the bioluminescent response to americium-241 and tritium were found: 1 – absence of effects (stress recognition), 2 – activation (adaptive response), and 3 – inhibition (suppression of physiological function, i.e. radiation toxicity). The effects were attributed to radiation hormesis phenomenon. Biological role of reactive oxygen species, secondary products of the radioactive decay, is discussed. The study suggests an approach to evaluation of non-toxic and toxic stages under conditions of chronic radioactive exposure. - Highlights: • Luminous bacteria demonstrate nonlinear dose-effect relation in radioactive solutions. • Response to low-dose radiation includes 3 stages: threshold, activation, inhibition. • ROS are responsible for low-dose effects of alpha-emitting radionuclides. • Luminous marine bacteria are a convenient tool to study radiation hormesis

Can we constrain the maximum value for the spin parameter of the super-massive objects in galactic nuclei without knowing their actual nature?

International Nuclear Information System (INIS)

Bambi, Cosimo

2011-01-01

In 4-dimensional General Relativity, black holes are described by the Kerr solution and are subject to the bound |a * |≤1, where a * is the black hole spin parameter. If current black hole candidates are not the black holes predicted in General Relativity, this bound does not hold and a * might exceed 1. In this Letter, I relax the Kerr black hole hypothesis and I find that the value of the spin parameter of the super-massive black hole candidates in galactic nuclei cannot be higher than about 1.2. A higher spin parameter would not be consistent with a radiative efficiency η>0.15, as observed at least for the most luminous AGN. While a rigorous proof is lacking, I conjecture that the bound |a * |≤1.2 is independent of the exact nature of these objects.

Rapid determination of the toxicity of quantum dots with luminous bacteria

Energy Technology Data Exchange (ETDEWEB)

Wang Lingling [Key Laboratory on Luminescence and Real-Time Analysis, Ministry of Education, College of Chemistry and Chemical Engineering, Southwest University, No. 2 Tiansheng Road, Beibei District, Chongqing 400715 (China); Zheng Huzhi, E-mail: zhenghz@swu.edu.cn [Key Laboratory on Luminescence and Real-Time Analysis, Ministry of Education, College of Chemistry and Chemical Engineering, Southwest University, No. 2 Tiansheng Road, Beibei District, Chongqing 400715 (China); Long Yijuan; Gao Mei; Hao Jianyu; Du Juan; Mao Xiaojiao; Zhou Dongbo [Key Laboratory on Luminescence and Real-Time Analysis, Ministry of Education, College of Chemistry and Chemical Engineering, Southwest University, No. 2 Tiansheng Road, Beibei District, Chongqing 400715 (China)

2010-05-15

In this paper, a novel method so-called bioluminescence inhibition assay with luminous bacteria (Photobacterium phosphoreum) was introduced to evaluate the toxicity of quantum dots. The bioassay was based on measuring the decrease of the light emitted by luminous bacteria. With obvious advantages of simplicity, rapidity and sensitivity, it can dramatically improve the efficiency of probing the toxicity of QDs. Based on this method, we systemically explored the effect of the composition and surface modification on QDs' toxicity. The experiment of composition effect was performed using three kinds of QDs, namely CdSe, CdTe and ZnS-AgInS{sub 2} QDs with the same stabilizer - dihydrolipoic acid. As for the effect of different stabilizers, mercaptoacetic acid, L-cysteine and dihydrolipoic acid stabilized CdSe were researched, respectively. Our results demonstrated that both the composition and surface modification were the important factors affecting the toxicity of QDs. In addition, a concentration dependence of toxicity was also found.

Rapid determination of the toxicity of quantum dots with luminous bacteria

International Nuclear Information System (INIS)

Wang Lingling; Zheng Huzhi; Long Yijuan; Gao Mei; Hao Jianyu; Du Juan; Mao Xiaojiao; Zhou Dongbo

2010-01-01

In this paper, a novel method so-called bioluminescence inhibition assay with luminous bacteria (Photobacterium phosphoreum) was introduced to evaluate the toxicity of quantum dots. The bioassay was based on measuring the decrease of the light emitted by luminous bacteria. With obvious advantages of simplicity, rapidity and sensitivity, it can dramatically improve the efficiency of probing the toxicity of QDs. Based on this method, we systemically explored the effect of the composition and surface modification on QDs' toxicity. The experiment of composition effect was performed using three kinds of QDs, namely CdSe, CdTe and ZnS-AgInS 2 QDs with the same stabilizer - dihydrolipoic acid. As for the effect of different stabilizers, mercaptoacetic acid, L-cysteine and dihydrolipoic acid stabilized CdSe were researched, respectively. Our results demonstrated that both the composition and surface modification were the important factors affecting the toxicity of QDs. In addition, a concentration dependence of toxicity was also found.

The formation of massive molecular filaments and massive stars triggered by a magnetohydrodynamic shock wave

Science.gov (United States)

Inoue, Tsuyoshi; Hennebelle, Patrick; Fukui, Yasuo; Matsumoto, Tomoaki; Iwasaki, Kazunari; Inutsuka, Shu-ichiro

2018-05-01

Recent observations suggest an that intensive molecular cloud collision can trigger massive star/cluster formation. The most important physical process caused by the collision is a shock compression. In this paper, the influence of a shock wave on the evolution of a molecular cloud is studied numerically by using isothermal magnetohydrodynamics simulations with the effect of self-gravity. Adaptive mesh refinement and sink particle techniques are used to follow the long-time evolution of the shocked cloud. We find that the shock compression of a turbulent inhomogeneous molecular cloud creates massive filaments, which lie perpendicularly to the background magnetic field, as we have pointed out in a previous paper. The massive filament shows global collapse along the filament, which feeds a sink particle located at the collapse center. We observe a high accretion rate \\dot{M}_acc> 10^{-4} M_{⊙}yr-1 that is high enough to allow the formation of even O-type stars. The most massive sink particle achieves M > 50 M_{⊙} in a few times 105 yr after the onset of the filament collapse.

Distribution and species composition of planktonic luminous bacteria in the Arabian Sea

Digital Repository Service at National Institute of Oceanography (India)

Ramaiah, N.; Chandramohan, D.

Distribution of the total viable heterotrophic bacteria and the luminous bacteria in the neretic and oceanic waters of the west coast of India was studied. Counts of viable heterotrophs fluctuated widely, generally with a decrease in their number...

Observations of Intermediate-mass Black Holes and Ultra-Luminous X-ray sources

Science.gov (United States)

Colbert, E. J. M.

2003-12-01

I will review various observations that suggest that intermediate-mass black holes (IMBHs) with masses ˜102-104 M⊙ exist in our Universe. I will also discuss some of the limitations of these observations. HST Observations of excess dark mass in globular cluster cores suggest IMBHs may be responsible, and some mass estimates from lensing experiments are nearly in the IMBH range. The intriguing Ultra-Luminous X-ray sources (ULXs, or IXOs) are off-nuclear X-ray point sources with X-ray luminosities LX ≳ 1039 erg s-1. ULXs are typically rare (1 in every 5 galaxies), and the nature of their ultra-luminous emission is currently debated. I will discuss the evidence for IMBHs in some ULXs, and briefly outline some phenomenology. Finally, I will discuss future observations that can be made to search for IMBHs.

Energetics of the molecular gas in the H2 luminous radio galaxy 3C 326: Evidence for negative AGN feedback

Science.gov (United States)

Nesvadba, N. P. H.; Boulanger, F.; Salomé, P.; Guillard, P.; Lehnert, M. D.; Ogle, P.; Appleton, P.; Falgarone, E.; Pineau Des Forets, G.

2010-10-01

We present a detailed analysis of the gas conditions in the H2 luminous radio galaxy 3C 326 N at z ~ 0.1, which has a low star-formation rate (SFR ~ 0.07 M⊙ yr-1) in spite of a gas surface density similar to those in starburst galaxies. Its star-formation efficiency is likely a factor ~10-50 lower than those of ordinary star-forming galaxies. Combining new IRAM CO emission-line interferometry with existing Spitzer mid-infrared spectroscopy, we find that the luminosity ratio of CO and pure rotational H2 line emission is factors 10-100 lower than what is usually found. This suggests that most of the molecular gas is warm. The Na D absorption-line profile of 3C 326 N in the optical suggests an outflow with a terminal velocity of ~-1800 km s-1 and a mass outflow rate of 30-40 M⊙ yr-1, which cannot be explained by star formation. The mechanical power implied by the wind, of order 1043 erg s-1, is comparable to the bolometric luminosity of the emission lines of ionized and molecular gas. To explain these observations, we propose a scenario where a small fraction of the mechanical energy of the radio jet is deposited in the interstellar medium of 3C 326 N, which powers the outflow, and the line emission through a mass, momentum and energy exchange between the different gas phases of the ISM. Dissipation times are of order 107-8 yrs, similar or greater than the typical jet lifetime. Small ratios of CO and PAH surface brightnesses in another 7 H2 luminous radio galaxies suggest that a similar form of AGN feedback could be lowering star-formation efficiencies in these galaxies in a similar way. The local demographics of radio-loud AGN suggests that secular gas cooling in massive early-type galaxies of ≥1011 M⊙ could generally be regulated through a fundamentally similar form of “maintenance-phase” AGN feedback. Based on observations carried out with the IRAM Plateau de Bure Interferometer.

Very massive runaway stars from three-body encounters

Science.gov (United States)

Gvaramadze, Vasilii V.; Gualandris, Alessia

2011-01-01

Very massive stars preferentially reside in the cores of their parent clusters and form binary or multiple systems. We study the role of tight very massive binaries in the origin of the field population of very massive stars. We performed numerical simulations of dynamical encounters between single (massive) stars and a very massive binary with parameters similar to those of the most massive known Galactic binaries, WR 20a and NGC 3603-A1. We found that these three-body encounters could be responsible for the origin of high peculiar velocities (≥70 km s-1) observed for some very massive (≥60-70 M⊙) runaway stars in the Milky Way and the Large Magellanic Cloud (e.g. λ Cep, BD+43°3654, Sk -67°22, BI 237, 30 Dor 016), which can hardly be explained within the framework of the binary-supernova scenario. The production of high-velocity massive stars via three-body encounters is accompanied by the recoil of the binary in the opposite direction to the ejected star. We show that the relative position of the very massive binary R145 and the runaway early B-type star Sk-69°206 on the sky is consistent with the possibility that both objects were ejected from the central cluster, R136, of the star-forming region 30 Doradus via the same dynamical event - a three-body encounter.

THE HOST GALAXY OF THE SUPER-LUMINOUS SN 2010gx AND LIMITS ON EXPLOSIVE 56Ni PRODUCTION

International Nuclear Information System (INIS)

Chen, Ting-Wan; Smartt, Stephen J.; Kotak, Rubina; McCrum, Matt; Fraser, Morgan; Bresolin, Fabio; Kudritzki, Rolf-Peter; Pastorello, Andrea; Valenti, Stefano

2013-01-01

Super-luminous supernovae have a tendency to occur in faint host galaxies which are likely to have low mass and low metallicity. While these extremely luminous explosions have been observed from z = 0.1 to 1.55, the closest explosions allow more detailed investigations of their host galaxies. We present a detailed analysis of the host galaxy of SN 2010gx (z = 0.23), one of the best studied super-luminous type Ic supernovae. The host is a dwarf galaxy (M g = –17.42 ± 0.17) with a high specific star formation rate. It has a remarkably low metallicity of 12 + log (O/H) = 7.5 ± 0.1 dex as determined from the detection of the [O III] λ4363 line. This is the first reliable metallicity determination of a super-luminous stripped-envelope supernova host. We collected deep multi-epoch imaging with Gemini + GMOS between 240 and 560 days after explosion to search for any sign of radioactive 56 Ni, which might provide further insights on the explosion mechanism and the progenitor's nature. We reach griz magnitudes of m AB ∼ 26, but do not detect SN 2010gx at these epochs. The limit implies that any 56 Ni production was similar to or below that of SN 1998bw (a luminous type Ic SN that produced around 0.4 M ☉ of 56 Ni). The low volumetric rates of these supernovae (∼10 –4 of the core-collapse population) could be qualitatively matched if the explosion mechanism requires a combination of low-metallicity (below 0.2 Z ☉ ), high progenitor mass (>60 M ☉ ) and high rotation rate (fastest 10% of rotators).

P1-12: Different Double-Pulse Distinguishability Among the Luminance Opponency, the Red-Green Opponency, and the Blue-Yellow Opponency

Directory of Open Access Journals (Sweden)

Lin Shi

2012-10-01

Full Text Available The inter-stimuli-interval (ISI thresholds of double pulses discrimination were measured to investigate the temporal distinguishability of double pulses of the luminance opponency, the red-green opponency, and the blue-yellow opponency. Double pulses were presented randomly in one of four quadrants, defined by a central fixation cross on a CRT display controlled by the real time sequencer (RTS of the VSG system in 42-bit color mode calibrated with less than 3% display error rate of the 1931 CIE luminance and chromatic coordinate. Each pulse was of duration 6.7 msec and included a Gaussian patch with gradation of tristimulus values from the peak to the background in equal-energy-white (the luminance opponency or isoluminance (the red-green and the blue-yellow opponency configuration. Eleven observers were asked to report the number of pulses (one or two observed while ISI was adjusted by a psi method. Psychometric functions were estimated using the cumulative distribution function of the extreme value distribution. The threshold was the ISI value corresponding with the rate of 63.21% correct answer. Significant differences were found among ISI thresholds of the luminance, blue-yellow, and red-green opponency. Results supported that the temporal distinguishability of double pulses of the luminance opponency, the red-green opponency, and the blue-yellow opponency were significantly different. The difference can be explained by the impulse response functions (IRF with various first peak time among the luminance opponency, the red-green opponency, and the blue-yellow opponency.

Epidemiology of massive transfusion

DEFF Research Database (Denmark)

Halmin, M A; Chiesa, F; Vasan, S K

2015-01-01

and to describe characteristics and mortality of massively transfused patients. Methods: We performed a retrospective cohort study based on the Scandinavian Donations and Transfusions (SCANDAT2) database, linking data on blood donation, blood components and transfused patients with inpatient- and population.......4% among women transfused for obstetrical bleeding. Mortality increased gradually with age and among all patients massively transfused at age 80 years, only 26% were alive [TABLE PRESENTED] after 5 years. The relative mortality, early after transfusion, was high and decreased with time since transfusion...

Reappraising the concept of massive transfusion in trauma

DEFF Research Database (Denmark)

Stanworth, Simon J; Morris, Timothy P; Gaarder, Christine

2010-01-01

ABSTRACT : INTRODUCTION : The massive-transfusion concept was introduced to recognize the dilutional complications resulting from large volumes of packed red blood cells (PRBCs). Definitions of massive transfusion vary and lack supporting clinical evidence. Damage-control resuscitation regimens...... of modern trauma care are targeted to the early correction of acute traumatic coagulopathy. The aim of this study was to identify a clinically relevant definition of trauma massive transfusion based on clinical outcomes. We also examined whether the concept was useful in that early prediction of massive...... transfusion as a concept in trauma has limited utility, and emphasis should be placed on identifying patients with massive hemorrhage and acute traumatic coagulopathy....

Seasonal and geographic distribution of luminous bacteria in the eastern mediterranean sea and the gulf of elat.

Science.gov (United States)

Yetinson, T; Shilo, M

1979-06-01

Luminous bacteria in the Mediterranean Sea and the Gulf of Aqaba-Elat have different distribution patterns. In the Mediterranean Sea, Beneckea harveyi is present all year round, with different subtypes alternating in summer and winter; Photobacterium fischeri was only present during the winter. In the Gulf of Elat, P. leiognathi is present throughout the water column in similar densities during the entire year. This constancy in distribution is presumably due to the near-constancy in water temperature. In summer, Photobacterium leiognathi is replaced by B. harveyi in coastal surface waters. In the hypersaline Bardawil lagoon, only B. harveyi types are present. P. fischeri, a major component of the Mediterranean Sea winter communities, is absent from the lagoon. Luminous Beneckea strains show a great diversity in properties, e.g. temperature range for growth, sensitivity to infection by phages, sensitivity to attack by Bdellovibrio strains, and differences in tolerance to high-salinity shock. Therefore, subdivision of the taxonomic cluster of B. harveyi into subtypes is indicated. The composition of the luminous bacteria communities may serve as indicators of different marine water bodies. The symbiotic luminous bacteria of the light organ of the common Gulf of Elat fish, Photoblepharon palbebratus steinitzi, is different from any of the types described.

A Semi-Automatic, Remote-Controlled Video Observation System for Transient Luminous Events

DEFF Research Database (Denmark)

Allin, Thomas Højgaard; Neubert, Torsten; Laursen, Steen

2003-01-01

In support for global ELF/VLF observations, HF measurements in France, and conjugate photometry/VLF observations in South Africa, we developed and operated a semi-automatic, remotely controlled video system for the observation of middle-atmospheric transient luminous events (TLEs). Installed...

An experimental study regarding diagnostic accuracy on image interpretation of the digital image film by using viewboxes of different luminance

International Nuclear Information System (INIS)

Song Shaojuan; Huang Ling; Liu Chuanya; Zhang Xiaojing

2009-01-01

Objective: To evaluate diagnostic accuracy of image interpretation using viewboxes at different luminance with ALVIM statistical phantom (TRG). Methods: A digital film of TRG image was obtained by exposing the phantom of TRG with Kodak DR 3000 using proper parameter. Viewboxes with three different luminance were selected from those used in daily work. The film of TRG was evaluated with these viewboxes of three different luminance by three different radiologists with experience of five, eight and sixteen years respectively. A grade scale of 5 was used to evaluate each row of signal and noise. According to the results and formula, the probabilities of true-positive [P(S/s)], false-positive [P(S/n)] and true answer (P det ) were obtained. Results: The three kinds of luminance used in viewboxes were: (3489± 256), (2231±220), (816±168) cd/m 2 . When the average luminance of viewbox was 3489 cd/m 2 , P det of 0.6,0.7,0.8 mm in bone substitute was 0.558±0.009, 0.788±0.008, 0.813±0.006, P det of 0.9, 1.0, 1.2 mm in muscle substitute was 0.663±0.010, 0.750±0.008, 0.933±0.005; When the average luminance of viewbox was 2231 cd/m 2 , P det of 0.6,0.7,0.8 mm in bone substitute was 0.525±0.013, 0.713±0.013,0.775±0.016, P det of 0.9,1.0,1.2 mm in muscle substitute was 0.613±0.019, 0.650± 0.013,0.850±0.019; When the average luminance of viewbox was 816 cd/m 2 , Pact of 0.6,0.7,0.8 mm in bone substitute was 0.475±0.022,0.550±0.018,0.688±0.020, P det of 0.9, 1.0, 1.2 mm in muscle substitute was 0.550±0.025,0.575±0.021,0.725±0.016. Viewboxes of different luminance were compared to one another by paired t-test. The results of comparison all had significant statistical differences (t=5.057 and 4.681, P<0.05). Conclusions: The image displayed by viewboxes at different luminance had significant influence on image interpretation. The higher the luminace of viewbox, the richer the information displayed, and the higher the accuracy of diagnosis. (authors)

Massive Black-Hole Binary Mergers: Dynamics, Environments & Expected Detections

Science.gov (United States)

Kelley, Luke Zoltan

2018-05-01

This thesis studies the populations and dynamics of massive black-hole binaries and their mergers, and explores the implications for electromagnetic and gravitational-wave signals that will be detected in the near future. Massive black-holes (MBH) reside in the centers of galaxies, and when galaxies merge, their MBH interact and often pair together. We base our study on the populations of MBH and galaxies from the `Illustris' cosmological hydrodynamic simulations. The bulk of the binary merger dynamics, however, are unresolved in cosmological simulations. We implement a suite of comprehensive physical models for the merger process, like dynamical friction and gravitational wave emission, which are added in post-processing. Contrary to many previous studies, we find that the most massive binaries with near equal-mass companions are the most efficient at coalescing; though the process still typically takes gigayears.From the data produced by these MBH binary populations and their dynamics, we calculate the expected gravitational wave (GW) signals: both the stochastic, GW background of countless unresolved sources, and the GW foreground of individually resolvable binaries which resound above the noise. Ongoing experiments, called pulsar timing arrays, are sensitive to both of these types of signals. We find that, while the current lack of detections is unsurprising, both the background and foreground will plausibly be detected in the next decade. Unlike previous studies which have predicted the foreground to be significantly harder to detect than the background, we find their typical amplitudes are comparable.With traditional electromagnetic observations, there has also been a dearth of confirmed detections of MBH binary systems. We use our binaries, combined with models of emission from accreting MBH systems, to make predictions for the occurrence rate of systems observable using photometric, periodic-variability surveys. These variables should be detectable in

Visual Perceptual Echo Reflects Learning of Regularities in Rapid Luminance Sequences.

Science.gov (United States)

Chang, Acer Y-C; Schwartzman, David J; VanRullen, Rufin; Kanai, Ryota; Seth, Anil K

2017-08-30

A novel neural signature of active visual processing has recently been described in the form of the "perceptual echo", in which the cross-correlation between a sequence of randomly fluctuating luminance values and occipital electrophysiological signals exhibits a long-lasting periodic (∼100 ms cycle) reverberation of the input stimulus (VanRullen and Macdonald, 2012). As yet, however, the mechanisms underlying the perceptual echo and its function remain unknown. Reasoning that natural visual signals often contain temporally predictable, though nonperiodic features, we hypothesized that the perceptual echo may reflect a periodic process associated with regularity learning. To test this hypothesis, we presented subjects with successive repetitions of a rapid nonperiodic luminance sequence, and examined the effects on the perceptual echo, finding that echo amplitude linearly increased with the number of presentations of a given luminance sequence. These data suggest that the perceptual echo reflects a neural signature of regularity learning.Furthermore, when a set of repeated sequences was followed by a sequence with inverted luminance polarities, the echo amplitude decreased to the same level evoked by a novel stimulus sequence. Crucially, when the original stimulus sequence was re-presented, the echo amplitude returned to a level consistent with the number of presentations of this sequence, indicating that the visual system retained sequence-specific information, for many seconds, even in the presence of intervening visual input. Altogether, our results reveal a previously undiscovered regularity learning mechanism within the human visual system, reflected by the perceptual echo. SIGNIFICANCE STATEMENT How the brain encodes and learns fast-changing but nonperiodic visual input remains unknown, even though such visual input characterizes natural scenes. We investigated whether the phenomenon of "perceptual echo" might index such learning. The perceptual echo is a

An Assessment of Luminance Imbalance with ANVIS at an Army Helicopter Training Airfield

National Research Council Canada - National Science Library

McLean, William

1997-01-01

One of the casual factors listed in a 1996 mid-air collision between two Australian Army helicopters in formation was a speculation of possible luminance imbalance between the right and left channels...

A Case of Massive Pleural Effusion: Pleurodesis by Bleomycin.

Science.gov (United States)

Hasan, R; Khan, O S; Aftabuddin, M; Razzaque, A M; Chowdhury, G A

2016-04-01

Malignant pleural effusion is a common complication of primary and metastatic pleural malignancies. Pleurodesis for the management of malignant pleural effusion is intended to achieve symphysis between parietal and visceral pleura, and to prevent relapse of pleural effusion. Many chemical agents are tried to induce inflammation and damage of the pleural mesothelial layer to achieve this symphysis. Hemorrhagic pleural effusion, especially in the right hemithorax commonly occurs as presentation of primary and metastatic pleural malignancies. This case reports massive right-sided hemorrhagic pleural effusion as the sole manifestation of primary lung cancer in a 45 year old man. Patient attended our department of thoracic surgery complaining of cough, shortness of breath and right sided chest pain. A chest X-ray and chest computer tomography (CT) radiograph shows right sided massive pleural effusion. Right sided tube thoracotomy done. Pleural fluid study was done. Fluid for cytopathology was positive for malignant cell. Computed tomography guided fine needle aspiration cytology from right lung lesion was also done. Diagnosis was as small cell carcinoma. Pleural effusion resolved after 9(th) post operative day of chest tube insertion. Bleomycin pleurodesis was done. Day after pleurodesis intra thoracic tube was removed and patient was discharged from hospital on 10(th) Post operative day with an advice to attend the oncology department for further treatment. The protocol of tube thoracostomy and chemical pleurodesis was almost always successful in giving symptomatic relief of respiratory distress for a considerable period of time. However, chemical pleurodesis is not possible in all cases of malignant pleural effusion because it has got potential complication including death.

The BAHAMAS project: the CMB-large-scale structure tension and the roles of massive neutrinos and galaxy formation

Science.gov (United States)

McCarthy, Ian G.; Bird, Simeon; Schaye, Joop; Harnois-Deraps, Joachim; Font, Andreea S.; van Waerbeke, Ludovic

2018-05-01

Recent studies have presented evidence for tension between the constraints on Ωm and σ8 from the cosmic microwave background (CMB) and measurements of large-scale structure (LSS). This tension can potentially be resolved by appealing to extensions of the standard model of cosmology and/or untreated systematic errors in the modelling of LSS, of which baryonic physics has been frequently suggested. We revisit this tension using, for the first time, carefully calibrated cosmological hydrodynamical simulations, which thus capture the backreaction of the baryons on the total matter distribution. We have extended the BAryons and HAloes of MAssive Sysmtes simulations to include a treatment of massive neutrinos, which currently represents the best-motivated extension to the standard model. We make synthetic thermal Sunyaev-Zel'dovich effect, weak galaxy lensing, and CMB lensing maps and compare to observed auto- and cross-power spectra from a wide range of recent observational surveys. We conclude that: (i) in general, there is tension between the primary CMB and LSS when adopting the standard model with minimal neutrino mass; (ii) after calibrating feedback processes to match the gas fractions of clusters, the remaining uncertainties in the baryonic physics modelling are insufficient to reconcile this tension; and (iii) if one accounts for internal tensions in the Planck CMB data set (by allowing the lensing amplitude, ALens, to vary), invoking a non-minimal neutrino mass, typically of 0.2-0.4 eV, can resolve the tension. This solution is fully consistent with separate constraints from the primary CMB and baryon acoustic oscillations.

Atomic Physics of Shocked Plasma in Winds of Massive Stars

Science.gov (United States)

Leutenegger, Maurice A.; Cohen, David H.; Owocki, Stanley P.

2012-01-01

High resolution diffraction grating spectra of X-ray emission from massive stars obtained with Chandra and XMM-Newton have revolutionized our understanding of their powerful, radiation-driven winds. Emission line shapes and line ratios provide diagnostics on a number of key wind parameters. Modeling of resolved emission line velocity profiles allows us to derive independent constraints on stellar mass-loss rates, leading to downward revisions of a factor of a few from previous measurements. Line ratios in He-like ions strongly constrain the spatial distribution of Xray emitting plasma, confirming the expectations of radiation hydrodynamic simulations that X-ray emission begins moderately close to the stellar surface and extends throughout the wind. Some outstanding questions remain, including the possibility of large optical depths in resonance lines, which is hinted at by differences in line shapes of resonance and intercombination lines from the same ion. Resonance scattering leads to nontrivial radiative transfer effects, and modeling it allows us to place constraints on shock size, density, and velocity structure

THE TRANSITION MASS-LOSS RATE: CALIBRATING THE ROLE OF LINE-DRIVEN WINDS IN MASSIVE STAR EVOLUTION

Energy Technology Data Exchange (ETDEWEB)

Vink, Jorick S.; Graefener, Goetz, E-mail: jsv@arm.ac.uk [Armagh Observatory, College Hill, BT61 9DG Armagh (United Kingdom)

2012-06-01

A debate has arisen regarding the importance of stationary versus eruptive mass loss for massive star evolution. The reason is that stellar winds have been found to be clumped, which results in the reduction of unclumped empirical mass-loss rates. Most stellar evolution models employ theoretical mass-loss rates which are already reduced by a moderate factor of {approx_equal}2-3 compared to non-corrected empirical rates. A key question is whether these reduced rates are of the correct order of magnitude, or if they should be reduced even further, which would mean that the alternative of eruptive mass loss becomes necessary. Here we introduce the transition mass-loss rate M-dot{sub trans} between O and Wolf-Rayet stars. Its novelty is that it is model independent. All that is required is postulating the spectroscopic transition point in a given data set, and determining the stellar luminosity, which is far less model dependent than the mass-loss rate. The transition mass-loss rate is subsequently used to calibrate stellar wind strength by its application to the Of/WNh stars in the Arches cluster. Good agreement is found with two alternative modeling/theoretical results, suggesting that the rates provided by current theoretical models are of the right order of magnitude in the {approx}50 M{sub Sun} mass range. Our results do not confirm the specific need for eruptive mass loss as luminous blue variables, and current stellar evolution modeling for Galactic massive stars seems sound. Mass loss through alternative mechanisms might still become necessary at lower masses, and/or metallicities, and the quantification of alternative mass loss is desirable.

THE TRANSITION MASS-LOSS RATE: CALIBRATING THE ROLE OF LINE-DRIVEN WINDS IN MASSIVE STAR EVOLUTION

International Nuclear Information System (INIS)

Vink, Jorick S.; Gräfener, Götz

2012-01-01

A debate has arisen regarding the importance of stationary versus eruptive mass loss for massive star evolution. The reason is that stellar winds have been found to be clumped, which results in the reduction of unclumped empirical mass-loss rates. Most stellar evolution models employ theoretical mass-loss rates which are already reduced by a moderate factor of ≅2-3 compared to non-corrected empirical rates. A key question is whether these reduced rates are of the correct order of magnitude, or if they should be reduced even further, which would mean that the alternative of eruptive mass loss becomes necessary. Here we introduce the transition mass-loss rate M-dot trans between O and Wolf-Rayet stars. Its novelty is that it is model independent. All that is required is postulating the spectroscopic transition point in a given data set, and determining the stellar luminosity, which is far less model dependent than the mass-loss rate. The transition mass-loss rate is subsequently used to calibrate stellar wind strength by its application to the Of/WNh stars in the Arches cluster. Good agreement is found with two alternative modeling/theoretical results, suggesting that the rates provided by current theoretical models are of the right order of magnitude in the ∼50 M ☉ mass range. Our results do not confirm the specific need for eruptive mass loss as luminous blue variables, and current stellar evolution modeling for Galactic massive stars seems sound. Mass loss through alternative mechanisms might still become necessary at lower masses, and/or metallicities, and the quantification of alternative mass loss is desirable.

Visual memory for random block patterns defined by luminance and color contrast

NARCIS (Netherlands)

Cornelissen, FW; Greenlee, MW

2000-01-01

We studied the ability of human subjects to memorize the visual information in computer-generated random block patterns defined either by luminance contrast, by color contrast, or by both. Memory performance declines rapidly with increasing inter-stimulus interval, showing a half-life of

Radiative Feedback from Massive Stars as Traced by Multiband Imaging and Spectroscopic Mosaics

Science.gov (United States)

Tielens, Alexander; "PDRs4ever" team

2018-06-01

Massive stars disrupt their natal molecular cloud material by dissociating molecules, ionizing atoms and molecules, and heating the gas and dust. These processes drive the evolution of interstellar matter in our Galaxy and throughout the Universe from the era of vigorous star formation at redshifts of 1-3, to the present day. Much of this interaction occurs in Photo-Dissociation Regions (PDRs) where far-ultraviolet photons of these stars create a largely neutral, but warm region of gas and dust. PDR emission dominates the IR spectra of star-forming galaxies and also provides a unique tool to study in detail the physical and chemical processes that are relevant for inter- and circumstellar media including diffuse clouds, molecular cloud and protoplanetary disk surfaces, globules, planetary nebulae, and starburst galaxies.We propose to provide template datasets designed to identify key PDR characteristics in the full 1-28 μm JWST spectra in order to guide the preparation of Cycle 2 proposals on star-forming regions in our Galaxy and beyond. We plan to obtain the first spatially resolved, high spectral resolution IR observations of a PDR using NIRCam, NIRSpec and MIRI. We will observe a nearby PDR with well-defined UV illumination in a typical massive star-forming region. JWST observations will, for the first time, spatially resolve and perform a tomography of the PDR, revealing the individual IR spectral signatures from the key zones and sub-regions within the ionized gas, the PDR and the molecular cloud. These data will test widely used theoretical models and extend them into the JWST era. We will assist the community interested in JWST observations of PDRs through several science-enabling products (maps of spectral features, template spectra, calibration of narrow/broad band filters in gas lines and PAH bands, data-interpretation tools e.g. to infer gas physical conditions or PAH and dust characteristics). This project is supported by a large international team of

How I treat patients with massive hemorrhage

DEFF Research Database (Denmark)

Johansson, Pär I; Stensballe, Jakob; Oliveri, Roberto

2014-01-01

Massive hemorrhage is associated with coagulopathy and high mortality. The transfusion guidelines up to 2006 recommended that resuscitation of massive hemorrhage should occur in successive steps using crystalloids, colloids and red blood cells (RBC) in the early phase, and plasma and platelets...... in the late phase. With the introduction of the cell-based model of hemostasis in the mid 1990ties, our understanding of the hemostatic process and of coagulopathy has improved. This has contributed to a change in resuscitation strategy and transfusion therapy of massive hemorrhage along with an acceptance...... outcome, although final evidence on outcome from randomized controlled trials are lacking. We here present how we in Copenhagen and Houston, today, manage patients with massive hemorrhage....

High-protein diet modifies colonic microbiota and luminal environment but not colonocyte metabolism in the rat model: the increased luminal bulk connection

OpenAIRE

LIU, Xinxin; BLOUIN, Jean-Marc; Santacruz, Arlette; Lan, Annaig; Andriamihaja, Mireille; Wilkanowicz, Sabina; Benetti, Pierre-Henri; Tomé, Daniel; Sanz, Yolanda; Blachier, Francois; Davila-Gay, Anne-Marie

2014-01-01

High-protein diets are used for body weight reduction, but consequences on the large intestine ecosystem are poorly known. Here, rats were fed for 15 days with either a normoproteic diet (NP, 14% protein) or a hyperproteic-hypoglucidic isocaloric diet (HP, 53% protein). Cecum and colon were recovered for analysis. Short- and branched-chain fatty acids, as well as lactate, succinate, formate, and ethanol contents, were markedly increased in the colonic luminal contents of HP rats (P < 0.05 or ...

Hybrid metal grid-polymer-carbon nanotube electrodes for high luminance organic light emitting diodes

International Nuclear Information System (INIS)

Sam, F Laurent M; Dabera, G Dinesha M R; Lai, Khue T; Mills, Christopher A; Rozanski, Lynn J; Silva, S Ravi P

2014-01-01

Organic light emitting diodes (OLEDs) incorporating grid transparent conducting electrodes (TCEs) with wide grid line spacing suffer from an inability to transfer charge carriers across the gaps in the grids to promote light emission in these areas. High luminance OLEDs fabricated using a hybrid TCE composed of poly(3,4-ethylenedioxythiophene) poly(styrenesulfonate) (PEDOT:PSS PH1000) or regioregular poly(3-hexylthiophene)-wrapped semiconducting single-walled carbon nanotubes (rrP3HT-SWCNT) in combination with a nanometre thin gold grid are reported here. OLEDs fabricated using the hybrid gold grid/PH1000 TCE have a luminance of 18 000 cd m −2 at 9 V; the same as the reference indium tin oxide (ITO) OLED. The gold grid/rrP3HT-SWCNT OLEDs have a lower luminance of 8260 cd m −2 at 9 V, which is likely due to a rougher rrP3HT-SWCNT surface. These results demonstrate that the hybrid gold grid/PH1000 TCE is a promising replacement for ITO in future plastic electronics applications including OLEDs and organic photovoltaics. For applications where surface roughness is not critical, e.g. electrochromic devices or discharge of static electricity, the gold grid/rrP3HT-SWCNT hybrid TCE can be employed. (paper)

On the singularities of massive superstring amplitudes

Energy Technology Data Exchange (ETDEWEB)

Foda, O.

1987-06-04

Superstring one-loop amplitudes with massive external states are shown to be in general ill-defined due to internal on-shell propagators. However, we argue that since any massive string state (in the uncompactified theory) has a finite lifetime to decay into massless particles, such amplitudes are not terms in the perturbative expansion of physical S-matrix elements: These can be defined only with massless external states. Consistent massive amplitudes repuire an off-shell formalism.

Massive supermultiplets in four-dimensional superstring theory

International Nuclear Information System (INIS)

Feng Wanzhe; Lüst, Dieter; Schlotterer, Oliver

2012-01-01

We extend the discussion of Feng et al. (2011) on massive Regge excitations on the first mass level of four-dimensional superstring theory. For the lightest massive modes of the open string sector, universal supermultiplets common to all four-dimensional compactifications with N=1,2 and N=4 spacetime supersymmetry are constructed respectively - both their vertex operators and their supersymmetry variations. Massive spinor helicity methods shed light on the interplay between individual polarization states.

Interleukin-10 neutralizing antibody for detection of intestinal luminal levels and as a dietary additive in Eimeria challenged broiler chicks.

Science.gov (United States)

Arendt, Maria K; Sand, Jordan M; Marcone, Taylor M; Cook, Mark E

2016-02-01

Interleukin-10 (IL-10) mRNA levels are increased within intestinal mucosa after Eimeria infection. IL-10 apical receptor presence on enterocytes suggests IL-10 is secreted into the intestinal lumen. Increased IL-10 has been shown to be central to the pathogenesis of numerous intracellular pathogens; we hypothesize luminal secretion of IL-10 enables Eimeria spp. infection in chickens. This study examines intestine luminal IL-10 levels and performance in broilers challenged with Eimeria when fed an anti-IL-10 antibody. Chicks were fed a diet (1 to 21 d) with control or anti-IL-10 antibody (0.34 g egg yolk antibody powder/Kg diet) with a saline or 10× dose of Advent coccidiosis vaccine on d 3. One chick per pen was euthanized on days 2, 4, 7, 10, 13, 16, and 19 post-challenge, bled, and intestines were collected for luminal fluid IL-10 concentrations. Body weight and feed intake were measured on d 21, and oocyst shedding was assessed on d 7 post-challenge. A significant Eimeria × antibody interaction on d 21 body weight (P < 0.05) showed chicks fed control antibody, but not anti-IL-10, had significant reductions in body weight when challenged with Eimeria spp. Oocyst shedding was increased with Eimeria challenge, but dietary antibody had no effect. Plasma carotenoid levels were reduced in Eimeria challenged chicks 4, 7, 10, and 16 days post-challenge compared to unchallenged chicks. Lack of an Eimeria × antibody interaction showed anti-IL-10 was not protective against Eimeria-induced decreases in plasma carotenoids. Eimeria challenge increased intestine luminal IL-10 on days 4 and 7 post-challenge in the cecum and jejunum, respectively, compared to unchallenged. Dietary anti-IL-10 decreased luminal IL-10 in the ileum on day 2 post-challenge when compared to control antibody fed chicks. No interaction between Eimeria challenge and antibody was observed on intestine luminal contents of IL-10, suggesting anti-IL-10 was ineffective at preventing increased Eimeria

Update on massive transfusion.

Science.gov (United States)

Pham, H P; Shaz, B H

2013-12-01

Massive haemorrhage requires massive transfusion (MT) to maintain adequate circulation and haemostasis. For optimal management of massively bleeding patients, regardless of aetiology (trauma, obstetrical, surgical), effective preparation and communication between transfusion and other laboratory services and clinical teams are essential. A well-defined MT protocol is a valuable tool to delineate how blood products are ordered, prepared, and delivered; determine laboratory algorithms to use as transfusion guidelines; and outline duties and facilitate communication between involved personnel. In MT patients, it is crucial to practice damage control resuscitation and to administer blood products early in the resuscitation. Trauma patients are often admitted with early trauma-induced coagulopathy (ETIC), which is associated with mortality; the aetiology of ETIC is likely multifactorial. Current data support that trauma patients treated with higher ratios of plasma and platelet to red blood cell transfusions have improved outcomes, but further clinical investigation is needed. Additionally, tranexamic acid has been shown to decrease the mortality in trauma patients requiring MT. Greater use of cryoprecipitate or fibrinogen concentrate might be beneficial in MT patients from obstetrical causes. The risks and benefits for other therapies (prothrombin complex concentrate, recombinant activated factor VII, or whole blood) are not clearly defined in MT patients. Throughout the resuscitation, the patient should be closely monitored and both metabolic and coagulation abnormalities corrected. Further studies are needed to clarify the optimal ratios of blood products, treatment based on underlying clinical disorder, use of alternative therapies, and integration of laboratory testing results in the management of massively bleeding patients.

CONFIRMATION OF ENHANCED DWARF-SENSITIVE ABSORPTION FEATURES IN THE SPECTRA OF MASSIVE ELLIPTICAL GALAXIES: FURTHER EVIDENCE FOR A NON-UNIVERSAL INITIAL MASS FUNCTION

International Nuclear Information System (INIS)

Van Dokkum, Pieter G.; Conroy, Charlie

2011-01-01

We recently found that massive cluster elliptical galaxies have strong Na I λ8183, 8195 and FeH λ9916 Wing-Ford band absorption, indicating the presence of a very large population of stars with masses ∼ sun . Here we test this result by comparing the elliptical galaxy spectra to those of luminous globular clusters associated with M31. These globular clusters have similar metallicities, abundance ratios, and ages as massive elliptical galaxies but their low dynamical mass-to-light ratios rule out steep stellar initial mass functions (IMFs). From high-quality Keck spectra we find that the dwarf-sensitive absorption lines in globular clusters are significantly weaker than in elliptical galaxies and consistent with normal IMFs. The differences in the Na I and Wing-Ford indices are 0.027 ± 0.007 mag and 0.017 ± 0.006 mag, respectively. We directly compare the two classes of objects by subtracting the averaged globular cluster spectrum from the averaged elliptical galaxy spectrum. The difference spectrum is well fit by the difference between a stellar population synthesis model with a bottom-heavy IMF and one with a bottom-light IMF. We speculate that the slope of the IMF may vary with velocity dispersion, although it is not yet clear what physical mechanism would be responsible for such a relation.

Effects of luminal flow and nucleotides on [Ca(2+)](i) in rabbit cortical collecting duct.

Science.gov (United States)

Woda, Craig B; Leite, Maurilo; Rohatgi, Rajeev; Satlin, Lisa M

2002-09-01

Nucleotide binding to purinergic P2 receptors contributes to the regulation of a variety of physiological functions in renal epithelial cells. Whereas P2 receptors have been functionally identified at the basolateral membrane of the cortical collecting duct (CCD), a final regulatory site of urinary Na(+), K(+), and acid-base excretion, controversy exists as to whether apical purinoceptors exist in this segment. Nor has the distribution of receptor subtypes present on the unique cell populations that constitute Ca(2+) the CCD been established. To examine this, we measured nucleotide-induced changes in intracellular Ca(2+) concentration ([Ca(2+)](i)) in fura 2-loaded rabbit CCDs microperfused in vitro. Resting [Ca(2+)](i) did not differ between principal and intercalated cells, averaging approximately 120 nM. An acute increase in tubular fluid flow rate, associated with a 20% increase in tubular diameter, led to increases in [Ca(2+)](i) in both cell types. Luminal perfusion of 100 microM UTP or ATP-gamma-S, in the absence of change in flow rate, caused a rapid and transient approximately fourfold increase in [Ca(2+)](i) in both cell types (P < 0.05). Luminal suramin, a nonspecific P2 receptor antagonist, blocked the nucleotide- but not flow-induced [Ca(2+)](i) transients. Luminal perfusion with a P2X (alpha,beta-methylene-ATP), P2X(7) (benzoyl-benzoyl-ATP), P2Y(1) (2-methylthio-ATP), or P2Y(4)/P2Y(6) (UDP) receptor agonist had no effect on [Ca(2+)](i). The nucleotide-induced [Ca(2+)](i) transients were inhibited by the inositol-1,4,5-triphosphate receptor blocker 2-aminoethoxydiphenyl borate, thapsigargin, which depletes internal Ca(2+) stores, luminal perfusion with a Ca(2+)-free perfusate, or the L-type Ca(2+) channel blocker nifedipine. These results suggest that luminal nucleotides activate apical P2Y(2) receptors in the CCD via pathways that require both internal Ca(2+) mobilization and extracellular Ca(2+) entry. The flow-induced rise in [Ca(2+)](i) is

Massive lepton pair production in massive quantum electrodynamics

International Nuclear Information System (INIS)

Raychaudhuri, P.

1976-01-01

The pp → l + +l - +x inclusive interaction has been studied at high energies in terms of the massive quantum electrodynamics. The differential cross-section (dsigma/dQ 2 ) is derived and proves to be proportional to Q -4 , where Q-mass of the lepton pair. Basic features of the cross-section are demonstrated to be consistent with the Drell-Yan model

Epidemiology of Massive Transfusion

DEFF Research Database (Denmark)

Halmin, Märit; Chiesa, Flaminia; Vasan, Senthil K

2016-01-01

in Sweden from 1987 and in Denmark from 1996. A total of 92,057 patients were included. Patients were followed until the end of 2012. MEASUREMENTS AND MAIN RESULTS: Descriptive statistics were used to characterize the patients and indications. Post transfusion mortality was expressed as crude 30-day...... mortality and as long-term mortality using the Kaplan-Meier method and using standardized mortality ratios. The incidence of massive transfusion was higher in Denmark (4.5 per 10,000) than in Sweden (2.5 per 10,000). The most common indication for massive transfusion was major surgery (61.2%) followed...

Outflow-Induced Dynamical and Radiative Instability in Stellar Envelopes with an Application to Luminous Blue Variables and Wolf-Rayet Stars

Science.gov (United States)

Stothers, Richard B.; Hansen, James E. (Technical Monitor)

2002-01-01

Theoretical models of the remnants of massive stars in a very hot, post-red-supergiant phase display no obvious instability if standard assumptions are made. However, the brightest observed classical luminous blue variables (LBVs) may well belong to such a phase. A simple time-dependent theory of moving stellar envelopes is developed in order to treat deep hydrodynamical disturbances caused by surface mass loss and to test the moving envelopes for dynamical instability. In the case of steady-state outflow, the theory reduces to the equivalent of the Castor, Abbott, and Klein formulation for optically thick winds at distances well above the sonic point. The time-dependent version indicates that the brightest and hottest LBVs are both dynamically and radiatively unstable, as a result of the substantial lowering of the generalized Eddington luminosity limit by the mass-loss acceleration. It is suggested that dynamical instability, by triggering secular cycles of mass loss, is primarily what differentiates LBVs from the purely radiatively unstable Wolf-Rayet stars. Furthermore, when accurate main-sequence mass-loss rates are used to calculate the evolutionary tracks, the predicted surface hydrogen and nitrogen abundances of the blue remnants agree much better with observations of the brightest LBVs than before.

On the singularities of massive superstring amplitudes

International Nuclear Information System (INIS)

Foda, O.

1987-01-01

Superstring one-loop amplitudes with massive external states are shown to be in general ill-defined due to internal on-shell propagators. However, we argue that since any massive string state (in the uncompactified theory) has a finite lifetime to decay into massless particles, such amplitudes are not terms in the perturbative expansion of physical S-matrix elements: These can be defined only with massless external states. Consistent massive amplitudes repuire an off-shell formalism. (orig.)

THE MOST LUMINOUS GALAXIES DISCOVERED BY WISE

Energy Technology Data Exchange (ETDEWEB)

Tsai, Chao-Wei; Eisenhardt, Peter R. M.; Stern, Daniel; Moustakas, Leonidas A. [Jet Propulsion Laboratory, California Institute of Technology, 4800 Oak Grove Dr., Pasadena, CA 91109 (United States); Wu, Jingwen; Wright, Edward L. [Department of Physics and Astronomy, UCLA, Los Angeles, CA 90095-1547 (United States); Assef, Roberto J. [Núcleo de Astronomía de la Facultad deIngeniería, Universidad Diego Portales, Av. Ejército Libertador 441, Santiago (Chile); Blain, Andrew W. [Department of Physics and Astronomy, University of Leicester, 1 University Road, Leicester, LE1 7RH (United Kingdom); Bridge, Carrie R.; Sayers, Jack [Division of Physics, Math, and Astronomy, California Institute of Technology, Pasadena, CA 91125 (United States); Benford, Dominic J.; Leisawitz, David T. [NASA Goddard Space Flight Center, Greenbelt, MD 20771 (United States); Cutri, Roc M.; Masci, Frank J.; Yan, Lin [Infrared Processing and Analysis Center, California Institute of Technology, Pasadena, CA 91125 (United States); Griffith, Roger L. [Department of Astronomy and Astrophysics, The Pennsylvania State University, 525 Davey Lab, University Park, PA 16802 (United States); Jarrett, Thomas H. [Astronomy Department, University of Cape Town, Private Bag X3, Rondebosch 7701 (South Africa); Lonsdale, Carol J. [National Radio Astronomy Observatory, 520 Edgemont Road, Charlottesville, VA 22903 (United States); Petty, Sara M. [Department of Physics, Virginia Tech, Blacksburg, VA 24061 (United States); Stanford, S. Adam, E-mail: Chao-Wei.Tsai@jpl.nasa.gov [Department of Physics, University of California Davis, One Shields Avenue, Davis, CA 95616 (United States); and others

2015-06-01

We present 20 Wide-field Infrared Survey Explorer (WISE)-selected galaxies with bolometric luminosities L{sub bol} > 10{sup 14} L{sub ☉}, including five with infrared luminosities L{sub IR} ≡ L{sub (rest} {sub 8–1000} {sub μm)} > 10{sup 14} L{sub ☉}. These “extremely luminous infrared galaxies,” or ELIRGs, were discovered using the “W1W2-dropout” selection criteria which requires marginal or non-detections at 3.4 and 4.6 μm (W1 and W2, respectively) but strong detections at 12 and 22 μm in the WISE survey. Their spectral energy distributions are dominated by emission at rest-frame 4–10 μm, suggesting that hot dust with T{sub d} ∼ 450 K is responsible for the high luminosities. These galaxies are likely powered by highly obscured active galactic nuclei (AGNs), and there is no evidence suggesting these systems are beamed or lensed. We compare this WISE-selected sample with 116 optically selected quasars that reach the same L{sub bol} level, corresponding to the most luminous unobscured quasars in the literature. We find that the rest-frame 5.8 and 7.8 μm luminosities of the WISE-selected ELIRGs can be 30%–80% higher than that of the unobscured quasars. The existence of AGNs with L{sub bol} > 10{sup 14} L{sub ☉} at z > 3 suggests that these supermassive black holes are born with large mass, or have very rapid mass assembly. For black hole seed masses ∼10{sup 3} M{sub ☉}, either sustained super-Eddington accretion is needed, or the radiative efficiency must be <15%, implying a black hole with slow spin, possibly due to chaotic accretion.

Nature versus nurture: Luminous blue variable nebulae in and near massive stellar clusters at the galactic center

Energy Technology Data Exchange (ETDEWEB)

Lau, R. M.; Herter, T. L.; Adams, J. D. [Astronomy Department, 202 Space Sciences Building, Cornell University, Ithaca, NY 14853-6801 (United States); Morris, M. R. [Department of Physics and Astronomy, University of California, Los Angeles, 430 Portola Plaza, Los Angeles, CA 90095-1547 (United States)

2014-04-20

Three luminous blue variables (LBVs) are located in and near the Quintuplet Cluster at the Galactic center: the Pistol Star, G0.120-0.048, and qF362. We present imaging at 19, 25, 31, and 37 μm of the region containing these three LBVs, obtained with SOFIA using FORCAST. We argue that Pistol and G0.120-0.048 are identical 'twins' that exhibit contrasting nebulae due to the external influence of their different environments. Our images reveal the asymmetric, compressed shell of hot dust surrounding the Pistol Star and provide the first detection of the thermal emission from the symmetric, hot dust envelope surrounding G0.120-0.048. However, no detection of hot dust associated with qF362 is made. Dust and gas composing the Pistol nebula are primarily heated and ionized by the nearby Quintuplet Cluster stars. The northern region of the Pistol nebula is decelerated due to the interaction with the high-velocity (2000 km s{sup –1}) winds from adjacent Wolf-Rayet Carbon (WC) stars. From fits to the spectral energy distribution (SED) of the Pistol nebula with the DustEM code we determine that the Pistol nebula is composed of a distribution of very small, transiently heated grains (10 to ∼ 35 Å) having a total dust mass of 0.03 M {sub ☉}, and that it exhibits a gradient of decreasing grain size from south to north due to differential sputtering by the winds from the WC stars. The total IR luminosity of the Pistol nebula is 5.2 × 10{sup 5} L {sub ☉}. Dust in the G0.120-0.048 nebula is primarily heated by the central star; however, the nebular gas is ionized externally by the Arches Cluster. Unlike the Pistol nebula, the G0.120-0.048 nebula is freely expanding into the surrounding medium. A grain size distribution identical to that of the non-sputtered region of the Pistol nebula satisfies the constraints placed on the G0.120-0.048 nebula from DustEM model fits to its SED and implies a total dust mass of 0.021 M {sub ☉}. The total IR luminosity of the G

Nature versus nurture: Luminous blue variable nebulae in and near massive stellar clusters at the galactic center

International Nuclear Information System (INIS)

Lau, R. M.; Herter, T. L.; Adams, J. D.; Morris, M. R.

2014-01-01

Three luminous blue variables (LBVs) are located in and near the Quintuplet Cluster at the Galactic center: the Pistol Star, G0.120-0.048, and qF362. We present imaging at 19, 25, 31, and 37 μm of the region containing these three LBVs, obtained with SOFIA using FORCAST. We argue that Pistol and G0.120-0.048 are identical 'twins' that exhibit contrasting nebulae due to the external influence of their different environments. Our images reveal the asymmetric, compressed shell of hot dust surrounding the Pistol Star and provide the first detection of the thermal emission from the symmetric, hot dust envelope surrounding G0.120-0.048. However, no detection of hot dust associated with qF362 is made. Dust and gas composing the Pistol nebula are primarily heated and ionized by the nearby Quintuplet Cluster stars. The northern region of the Pistol nebula is decelerated due to the interaction with the high-velocity (2000 km s –1 ) winds from adjacent Wolf-Rayet Carbon (WC) stars. From fits to the spectral energy distribution (SED) of the Pistol nebula with the DustEM code we determine that the Pistol nebula is composed of a distribution of very small, transiently heated grains (10 to ∼ 35 Å) having a total dust mass of 0.03 M ☉ , and that it exhibits a gradient of decreasing grain size from south to north due to differential sputtering by the winds from the WC stars. The total IR luminosity of the Pistol nebula is 5.2 × 10 5 L ☉ . Dust in the G0.120-0.048 nebula is primarily heated by the central star; however, the nebular gas is ionized externally by the Arches Cluster. Unlike the Pistol nebula, the G0.120-0.048 nebula is freely expanding into the surrounding medium. A grain size distribution identical to that of the non-sputtered region of the Pistol nebula satisfies the constraints placed on the G0.120-0.048 nebula from DustEM model fits to its SED and implies a total dust mass of 0.021 M ☉ . The total IR luminosity of the G0.120-0.048 nebula is �

An analytical model for backscattered luminance in fog: comparisons with Monte Carlo computations and experimental results

International Nuclear Information System (INIS)

Taillade, Frédéric; Dumont, Eric; Belin, Etienne

2008-01-01

We propose an analytical model for backscattered luminance in fog and derive an expression for the visibility signal-to-noise ratio as a function of meteorological visibility distance. The model uses single scattering processes. It is based on the Mie theory and the geometry of the optical device (emitter and receiver). In particular, we present an overlap function and take the phase function of fog into account. The results of the backscattered luminance obtained with our analytical model are compared to simulations made using the Monte Carlo method based on multiple scattering processes. An excellent agreement is found in that the discrepancy between the results is smaller than the Monte Carlo standard uncertainties. If we take no account of the geometry of the optical device, the results of the model-estimated backscattered luminance differ from the simulations by a factor 20. We also conclude that the signal-to-noise ratio computed with the Monte Carlo method and our analytical model is in good agreement with experimental results since the mean difference between the calculations and experimental measurements is smaller than the experimental uncertainty

NO CLEAR SUBMILLIMETER SIGNATURE OF SUPPRESSED STAR FORMATION AMONG X-RAY LUMINOUS ACTIVE GALACTIC NUCLEI

Energy Technology Data Exchange (ETDEWEB)

Harrison, C. M.; Alexander, D. M.; Mullaney, J. R.; Del Moro, A.; Rovilos, E. [Department of Physics, Durham University, South Road, Durham DH1 3LE (United Kingdom); Altieri, B.; Coia, D. [Herschel Science Centre, European Space Astronomy Centre, Villanueva de la Canada, E-28691 Madrid (Spain); Charmandaris, V. [Department of Physics and Institute of Theoretical and Computation Physics, University of Crete, 71003 Heraklion (Greece); Daddi, E.; Le Floc' h, E.; Leiton, R. [Laboratoire AIM, CEA/DSM-CNRS-Universite Paris Diderot, Irfu/Service d Astrophysique, CEA-Saclay, Orme des Merisiers, F-91191 Gif-sur-Yvette Cedex (France); Dannerbauer, H. [Insitut fuer Astrophysik, Universitaet Wien, Tuerkenschanzstrasse 17, A-1180 Wien (Austria); Dasyra, K. [Observatoire de Paris, LERMA (CNRS:UMR8112), 61 Av. de l' Observatoire, F-75014 Paris (France); Dickinson, M.; Kartaltepe, J. [National Optical Astronomy Observatory, 950 North Cherry Avenue, Tucson, AZ 85719 (United States); Hickox, R. C. [Department of Physics and Astronomy, Dartmouth College, 6127 Wilder Laboratory, Hanover, NH 03755 (United States); Ivison, R. J. [UK Astronomy Technology Centre, Royal Observatory, Blackford Hill, Edinburgh EH9 3HJ (United Kingdom); Magnelli, B.; Popesso, P.; Rosario, D. [Max-Planck-Institut fuer Extraterrestrische Physik (MPE), Postfach 1312, D-85741 Garching (Germany); and others

2012-11-20

Many theoretical models require powerful active galactic nuclei (AGNs) to suppress star formation in distant galaxies and reproduce the observed properties of today's massive galaxies. A recent study based on Herschel-SPIRE submillimeter observations claimed to provide direct support for this picture, reporting a significant decrease in the mean star formation rates (SFRs) of the most luminous AGNs (L{sub X} >10{sup 44} erg s{sup -1}) at z Almost-Equal-To 1-3 in the Chandra Deep Field-North (CDF-N). In this Letter, we extend these results using Herschel-SPIRE 250 {mu}m data in the COSMOS and Chandra Deep Field-South fields to achieve an order-of-magnitude improvement in the number of sources at L{sub X} >10{sup 44} erg s{sup -1}. On the basis of our analysis, we find no strong evidence for suppressed star formation in L{sub X} >10{sup 44} erg s{sup -1} AGNs at z Almost-Equal-To 1-3. The mean SFRs of the AGNs are constant over the broad X-ray luminosity range of L{sub X} Almost-Equal-To 10{sup 43}-10{sup 45} erg s{sup -1} (with mean SFRs consistent with typical star-forming galaxies at z Almost-Equal-To 2; (SFRs) Almost-Equal-To 100-200 M{sub Sun} yr{sup -1}). We suggest that the previous CDF-N results were likely due to low number statistics. We discuss our results in the context of current theoretical models.

A new method for calibrating perceptual salience across dimensions in infants: the case of color vs. luminance.

Science.gov (United States)

Kaldy, Zsuzsa; Blaser, Erik A; Leslie, Alan M

2006-09-01

We report a new method for calibrating differences in perceptual salience across feature dimensions, in infants. The problem of inter-dimensional salience arises in many areas of infant studies, but a general method for addressing the problem has not previously been described. Our method is based on a preferential looking paradigm, adapted to determine the relative salience of two stimuli. We report here on the case of stimuli differing in color and luminance, though the method has wider potential. We were able to determine on a psychophysical curve the point at which a color contrast was equally salient to infants as a given luminance contrast. We then used these calibrated, 'iso-salient' stimuli in an object memory study. Results showed that 6.5-month-old infants noticed a color, but not a luminance, change while tracking an occluded object. Our method should have numerous applications in the study of bottom-up effects on infant attention and visual working memory.

Thermodynamics inducing massive particles' tunneling and cosmic censorship

Energy Technology Data Exchange (ETDEWEB)

Zhang, Baocheng [Chinese Academy of Sciences, State Key Laboratory of Magnetic Resonances and Atomic and Molecular Physics, Wuhan Institute of Physics and Mathematics, Wuhan (China); Graduate University of Chinese Academy of Sciences, Beijing (China); Cai, Qing-yu [Chinese Academy of Sciences, State Key Laboratory of Magnetic Resonances and Atomic and Molecular Physics, Wuhan Institute of Physics and Mathematics, Wuhan (China); Zhan, Ming-sheng [Chinese Academy of Sciences, State Key Laboratory of Magnetic Resonances and Atomic and Molecular Physics, Wuhan Institute of Physics and Mathematics, Wuhan (China); Chinese Academy of Sciences, Center for Cold Atom Physics, Wuhan (China)

2010-08-15

By calculating the change of entropy, we prove that the first law of black hole thermodynamics leads to the tunneling probability of massive particles through the horizon, including the tunneling probability of massive charged particles from the Reissner-Nordstroem black hole and the Kerr-Newman black hole. Novelly, we find the trajectories of massive particles are close to that of massless particles near the horizon, although the trajectories of massive charged particles may be affected by electromagnetic forces. We show that Hawking radiation as massive particles tunneling does not lead to violation of the weak cosmic-censorship conjecture. (orig.)

Study of luminous emissions associated to electron emissions in radiofrequency cavities; Etude des emissions lumineuses associees aux emissions electroniques dans les cavites hyperfrequences

Energy Technology Data Exchange (ETDEWEB)

Maissa, S

1996-11-26

This study investigates luminous emissions simultaneously to electron emissions and examines their features in order to better understand the field electron emission phenomenon. A RF cavity, operating at room temperature and in pulsed mode, joined to a sophisticated experimental apparatus has been especially developed. The electron and luminous emissions are investigated on cleaned or with metallic, graphitic and dielectric particles contaminated RF surfaces in order to study their influence on these phenomena. During the surface processing, unstable luminous spots glowing during one RF pulse are detected. Their apparition is promoted in the vicinity of the metallic particles or scratches. Two hypotheses could explain their origin: the presence of micro-plasmas associated to electronic explosive emission during processing or the thermal radiation of the melted metal during this emission. Stable luminous spots glowing during several RF pulses are also detected and appear to increase on RF surfaces contaminated with dielectric particles, leading to strong and explosive luminous emissions. Two interpretations are considered: the initiation of surface breakdowns on the dielectric particles or the heating by the RF field at temperatures sufficiently intense to provoke their thermal radiation then their explosion. Finally a superconducting cavity has been adapted to observe luminous spots, which differ from the former ones bu their star shape and could be associated to micro-plasmas, revealed by the starbursts observed on superconducting cavity walls. (author) 102 refs.

Exact Solutions in 3D New Massive Gravity

Science.gov (United States)

Ahmedov, Haji; Aliev, Alikram N.

2011-01-01

We show that the field equations of new massive gravity (NMG) consist of a massive (tensorial) Klein-Gordon-type equation with a curvature-squared source term and a constraint equation. We also show that, for algebraic type D and N spacetimes, the field equations of topologically massive gravity (TMG) can be thought of as the “square root” of the massive Klein-Gordon-type equation. Using this fact, we establish a simple framework for mapping all types D and N solutions of TMG into NMG. Finally, we present new examples of types D and N solutions to NMG.

A stent for co-delivering paclitaxel and nitric oxide from abluminal and luminal surfaces: Preparation, surface characterization, and in vitro drug release studies

Energy Technology Data Exchange (ETDEWEB)

Gallo, Annemarie; Mani, Gopinath, E-mail: Gopinath.Mani@usd.edu

2013-08-15

Most drug-eluting stents currently available are coated with anti-proliferative drugs on both abluminal (toward blood vessel wall) and luminal (toward lumen) surfaces to prevent neointimal hyperplasia. While the abluminal delivery of anti-proliferative drugs is useful for controlling neointimal hyperplasia, the luminal delivery of such drugs impairs or prevents endothelialization which causes late stent thrombosis. This research is focused on developing a bidirectional dual drug-eluting stent to co-deliver an anti-proliferative agent (paclitaxel – PAT) and an endothelial cell promoting agent (nitric oxide – NO) from abluminal and luminal surfaces of the stent, respectively. Phosphonoacetic acid, a polymer-free drug delivery platform, was initially coated on the stents. Then, the PAT and NO donor drugs were co-coated on the abluminal and luminal stent surfaces, respectively. The co-coating of drugs was collectively confirmed by the surface characterization techniques such as Fourier transform infrared spectroscopy, scanning electron microscopy (SEM), 3D optical surface profilometry, and contact angle goniometry. SEM showed that the integrity of the co-coating of drugs was maintained without delamination or cracks formation occurring during the stent expansion experiments. In vitro drug release studies showed that the PAT was released from the abluminal stent surfaces in a biphasic manner, which is an initial burst followed by a slow and sustained release. The NO was burst released from the luminal stent surfaces. Thus, this study demonstrated the co-delivery of PAT and NO from abluminal and luminal stent surfaces, respectively. The stent developed in this study has potential applications in inhibiting neointimal hyperplasia as well as encouraging luminal endothelialization to prevent late stent thrombosis.

A stent for co-delivering paclitaxel and nitric oxide from abluminal and luminal surfaces: Preparation, surface characterization, and in vitro drug release studies

International Nuclear Information System (INIS)

Gallo, Annemarie; Mani, Gopinath

2013-01-01

Most drug-eluting stents currently available are coated with anti-proliferative drugs on both abluminal (toward blood vessel wall) and luminal (toward lumen) surfaces to prevent neointimal hyperplasia. While the abluminal delivery of anti-proliferative drugs is useful for controlling neointimal hyperplasia, the luminal delivery of such drugs impairs or prevents endothelialization which causes late stent thrombosis. This research is focused on developing a bidirectional dual drug-eluting stent to co-deliver an anti-proliferative agent (paclitaxel – PAT) and an endothelial cell promoting agent (nitric oxide – NO) from abluminal and luminal surfaces of the stent, respectively. Phosphonoacetic acid, a polymer-free drug delivery platform, was initially coated on the stents. Then, the PAT and NO donor drugs were co-coated on the abluminal and luminal stent surfaces, respectively. The co-coating of drugs was collectively confirmed by the surface characterization techniques such as Fourier transform infrared spectroscopy, scanning electron microscopy (SEM), 3D optical surface profilometry, and contact angle goniometry. SEM showed that the integrity of the co-coating of drugs was maintained without delamination or cracks formation occurring during the stent expansion experiments. In vitro drug release studies showed that the PAT was released from the abluminal stent surfaces in a biphasic manner, which is an initial burst followed by a slow and sustained release. The NO was burst released from the luminal stent surfaces. Thus, this study demonstrated the co-delivery of PAT and NO from abluminal and luminal stent surfaces, respectively. The stent developed in this study has potential applications in inhibiting neointimal hyperplasia as well as encouraging luminal endothelialization to prevent late stent thrombosis.

Dynamics of massive black holes as a possible candidate of Galactic dark matter

Science.gov (United States)

Xu, Guohong; Ostriker, Jeremiah P.

1994-01-01

If the dark halo of the Galaxy is comprised of massive black holes (MBHs), then those within approximately 1 kpc will spiral to the center, where they will interact with one another, forming binaries which contract, owing to further dynamical friction, and then possibly merge to become more massive objects by emission of gravitational radiation. If successive mergers would invariably lead, as has been proposed by various authors, to the formation of a very massive nucleus of 10(exp 8) solar mass, then the idea of MBHs as a dark matter candidate could be excluded on observational grounds, since the observed limit (or value) for a Galactic central black hole is approximately 10(exp 6.5) solar mass. But, if successive mergers are delayed or prevented by other processes, such as the gravitational slingshot or rocket effect of gravitational radiation, then a large mass accumulation will not occur. In order to resolve this issue, we perform detailed N-body simulations using a modfied Aarseth code to explore the dynamical behavior of the MBHs, and we find that for a 'best estimate' model of the Galaxy a runaway does not occur. The code treates the MBHs as subject to the primary gravitational forces of one another and to the smooth stellar distribution, as well as the secondary perturbations in their orbits due to another and to the smooth stellar distribution, as well as the secondary perturbations in their orbits due to dynamical friction and gravitational radiation. Instead of a runaway, three-body interactions between hard binaries and single MBHs eject massive objects before accumulation of more than a few units, so that typically the center will contain zero, one, or two MBHs. We study how the situation depends in detail on the mass per MBH, the rotation of the halo, the mass distribution within the Galaxy, and other parameters. A runaway will most sensitively depend on the ratio of initial (spheroid/halo) central mass densities and secondarily on the typical values

Selective response of human airway epithelia to luminal but not serosal solution hypertonicity. Possible role for proximal airway epithelia as an osmolality transducer

DEFF Research Database (Denmark)

Willumsen, Niels J.; Davis, C.W.; Boucher, R.C.

1994-01-01

exposure (10 min) to 430 mosM luminal solution elicited no regulation of any parameter. Optical measurements revealed a reduction in the thickness of preparations only in response to luminal hypertonic solutions. We conclude that (a) airway epithelial cells exhibit asymmetric water transport properties......- secretion; and (d) cell volume loss increases the resistance of the paracellular path. We speculate that these properties configure human nasal epithelium to behave as an osmotic sensor, transducing information about luminal solutions to the airway wall....

The most luminous type 2 Active Galactic Nuclei of the Swift/ BAT catalog : Are they different?

Science.gov (United States)

Baer, Rudolf Erik; Oh, Kyuseok; Koss, Michael; Wong, Ivy; Schawinski, Kevin

2018-01-01

We present an analysis of the most luminous obscured AGN of the Swift/BAT 70 month catalog, which is based on an all-sky survey in the 14 – 195 keV energy range. This survey identified 838 AGN. Excluding Blazars and AGN close ( |gb| BAT 70 month catalog and from a specific observation campaign in order to analyze the relationship of their luminosity to black hole mass and their Eddington ratios. We discuss whether these most luminous type 2 AGN have common characteristics, which differentiate them from all the type 2 AGN in the 70 month catalog.

Dual-energy index value of luminal air in fecal-tagging computed tomography colonography: findings and impact on electronic cleansing.

Science.gov (United States)

Cai, Wenli; Zhang, Da; Lee, June-Goo; Shirai, Yu; Kim, Se Hyung; Yoshida, Hiroyuki

2013-01-01

The purpose of our study was to measure the dual-energy index (DEI) value of colonic luminal air in both phantom and clinical fecal-tagging dual-energy computed tomography (CT) colonography (DE-CTC) images and to demonstrate its impact on dual-energy electronic cleansing. For the phantom study, a custom-ordered colon phantom was scanned by a dual-energy CT scanner (SOMATON Definition Flash; Siemens Healthcare, Forchheim, Germany) at two photon energies: 80 and 140 kVp. Before imaging, the phantom was filled with a 300-mL mixture of simulated fecal materials tagged by a nonionic iodinated contrast agent at three contrast concentrations: 20, 40, and 60 mg/mL. Ten regions-of-interest (ROIs) were randomly placed in each of the colonic luminal air, abdominal fat, bony structure, and tagged material in each scan. For the clinical study, 22 DE-CTC (80 and 140 kVp) patient cases were collected, who underwent a low-fiber, low-residue diet bowel preparation and orally administered iodine-based fecal tagging. Twenty ROIs were randomly placed in each of the colonic luminal air, abdominal fat, abdominal soft tissue, and tagged fecal material in each scan. For each ROI, the mean CT values in both 80- and 140-kVp images were measured, and then its DEI was calculated. In the phantom study, the mean DEI values of luminal air were 0.270, 0.298, 0.386, and 0.402 for the four groups of tagging conditions: no tagged material and tagged with three groups of contrast concentrations at 20, 40, and 60 mg/mL. In the clinical study, the mean DEI values were 0.341, -0.012, -0.002, and 0.188 for colonic luminal air, abdominal fat, abdominal soft tissue, and tagged fecal material, respectively. In our study, we observed that the DEI values of colonic luminal air in DE-CTC images (>0.10) were substantially higher than the theoretical value of 0.0063. In addition, the observed DEI values of colonic luminal air were significantly higher than those of soft tissue. These findings have an important

Spacetime structure of massive Majorana particles and massive gravitino

CERN Document Server

Ahluwalia, D V

2003-01-01

The profound difference between Dirac and Majorana particles is traced back to the possibility of having physically different constructs in the (1/2, 0) 0 (0,1/2) representation space. Contrary to Dirac particles, Majorana-particle propagators are shown to differ from the simple linear gamma mu p submu, structure. Furthermore, neither Majorana particles, nor their antiparticles can be associated with a well defined arrow of time. The inevitable consequence of this peculiarity is the particle-antiparticle metamorphosis giving rise to neutrinoless double beta decay, on the one side, and enabling spin-1/2 fields to act as gauge fields, gauginos, on the other side. The second part of the lecture notes is devoted to massive gravitino. We argue that a spin measurement in the rest frame for an unpolarized ensemble of massive gravitino, associated with the spinor-vector [(1/2, 0) 0 (0,1/2)] 0 (1/2,1/2) representation space, would yield the results 3/2 with probability one half, and 1/2 with probability one half. The ...

How Very Massive Metal Free Stars Start Cosmological Reionization

International Nuclear Information System (INIS)

Wise, John H.; Abel, Tom

2007-01-01

The initial conditions and relevant physics for the formation of the earliest galaxies are well specified in the concordance cosmology. Using ab initio cosmological Eulerian adaptive mesh refinement radiation hydrodynamical calculations, we discuss how very massive stars start the process of cosmological reionization. The models include non-equilibrium primordial gas chemistry and cooling processes and accurate radiation transport in the Case B approximation using adaptively ray traced photon packages, retaining the time derivative in the transport equation. Supernova feedback is modeled by thermal explosions triggered at parsec scales. All calculations resolve the local Jeans length by at least 16 grid cells at all times and as such cover a spatial dynamic range of ∼10 6 . These first sources of reionization are highly intermittent and anisotropic and first photoionize the small scales voids surrounding the halos they form in, rather than the dense filaments they are embedded in. As the merging objects form larger, dwarf sized galaxies, the escape fraction of UV radiation decreases and the H II regions only break out on some sides of the galaxies making them even more anisotropic. In three cases, SN blast waves induce star formation in overdense regions that were formed earlier from ionization front instabilities. These stars form tens of parsecs away from the center of their parent DM halo. Approximately 5 ionizing photons are needed per sustained ionization when star formation in 10 6 M · halos are dominant in the calculation. As the halos become larger than ∼10 7 M # circle d ot#, the ionizing photon escape fraction decreases, which in turn increases the number of photons per ionization to 15--50, in calculations with stellar feedback only. Supernova feedback in these more massive halos creates a more diffuse medium, allowing the stellar radiation to escape more easily and maintaining the ratio of 5 ionizing photons per sustained ionization

Massive vector fields and black holes

International Nuclear Information System (INIS)

Frolov, V.P.

1977-04-01

A massive vector field inside the event horizon created by the static sources located outside the black hole is investigated. It is shown that the back reaction of such a field on the metric near r = 0 cannot be neglected. The possibility of the space-time structure changing near r = 0 due to the external massive field is discussed

Effect of americium-241 on luminous bacteria. Role of peroxides

Energy Technology Data Exchange (ETDEWEB)

Alexandrova, M., E-mail: maka-alexandrova@rambler.r [Siberian Federal University, Svobodny 79, 660041 Krasnoyarsk (Russian Federation); Rozhko, T. [Siberian Federal University, Svobodny 79, 660041 Krasnoyarsk (Russian Federation); Vydryakova, G. [Institute of Biophysics SB RAS, Akademgorodok 50, 660036 Krasnoyarsk (Russian Federation); Kudryasheva, N. [Siberian Federal University, Svobodny 79, 660041 Krasnoyarsk (Russian Federation); Institute of Biophysics SB RAS, Akademgorodok 50, 660036 Krasnoyarsk (Russian Federation)

2011-04-15

The effect of americium-241 ({sup 241}Am), an alpha-emitting radionuclide of high specific activity, on luminous bacteria Photobacterium phosphoreum was studied. Traces of {sup 241}Am in nutrient media (0.16-6.67 kBq/L) suppressed the growth of bacteria, but enhanced luminescence intensity and quantum yield at room temperature. Lower temperature (4 {sup o}C) increased the time of bacterial luminescence and revealed a stage of bioluminescence inhibition after 150 h of bioluminescence registration start. The role of conditions of exposure the bacterial cells to the {sup 241}Am is discussed. The effect of {sup 241}Am on luminous bacteria was attributed to peroxide compounds generated in water solutions as secondary products of radioactive decay. Increase of peroxide concentration in {sup 241}Am solutions was demonstrated; and the similarity of {sup 241}Am and hydrogen peroxide effects on bacterial luminescence was revealed. The study provides a scientific basis for elaboration of bioluminescence-based assay to monitor radiotoxicity of alpha-emitting radionuclides in aquatic solutions. - Highlights: {yields} Am-241 in water solutions (A = 0.16-6.7 kBq/L) suppresses bacterial growth.{yields} Am-241 (A = 0.16-6.7 kBq/L) stimulate bacterial luminescence. {yields} Peroxides, secondary radiolysis products, cause increase of bacterial luminescence.

Modeling of luminance distribution in CAVE-type virtual reality systems

Science.gov (United States)

Meironke, Michał; Mazikowski, Adam

2017-08-01

At present, one of the most advanced virtual reality systems are CAVE-type (Cave Automatic Virtual Environment) installations. Such systems are usually consisted of four, five or six projection screens and in case of six screens arranged in form of a cube. Providing the user with a high level of immersion feeling in such systems is largely dependent of optical properties of the system. The modeling of physical phenomena plays nowadays a huge role in the most fields of science and technology. It allows to simulate work of device without a need to make any changes in the physical constructions. In this paper distribution of luminance in CAVE-type virtual reality systems were modelled. Calculations were performed for the model of 6-walled CAVE-type installation, based on Immersive 3D Visualization Laboratory, situated at the Faculty of Electronics, Telecommunications and Informatics at the Gdańsk University of Technology. Tests have been carried out for two different scattering distribution of the screen material in order to check how these characteristicinfluence on the luminance distribution of the whole CAVE. The basis assumption and simplification of modeled CAVE-type installation and results were presented. The brief discussion about the results and usefulness of developed model were also carried out.

EVIDENCE FOR REDUCED SPECIFIC STAR FORMATION RATES IN THE CENTERS OF MASSIVE GALAXIES AT z  = 4

Energy Technology Data Exchange (ETDEWEB)

Jung, Intae; Finkelstein, Steven L. [Department of Astronomy, The University of Texas at Austin, Austin, TX 78712 (United States); Song, Mimi; Straughn, Amber N. [Astrophysics Science Division, Goddard Space Flight Center, Code 665, Greenbelt, MD 20771 (United States); Dickinson, Mark [National Optical Astronomy Observatory, Tucson, AZ 85719 (United States); Dekel, Avishai [Center for Astrophysics and Planetary Science, Racah Institute of Physics, The Hebrew University, Jerusalem 91904 (Israel); Ferguson, Henry C.; Koekemoer, Anton M.; Ryan, Russell E. Jr.; Salmon, Brett [Space Telescope Science Institute, 3700 San Martin Drive, Baltimore, MD 21218 (United States); Fontana, Adriano [INAF—Osservatorio Astronomico di Roma, via di Frascati 33, I-00040, Monte Porzio Catone (Italy); Lu, Yu [The Observatories, The Carnegie Institution for Science, 813 Santa Barbara Street, Pasadena, CA 91101 (United States); Mobasher, Bahram [Department of Physics and Astronomy, University of California, Riverside, CA 92521 (United States); Papovich, Casey, E-mail: itjung@astro.as.utexas.edu [George P. and Cynthia W. Mitchell Institute for Fundamental Physics and Astronomy, Department of Physics and Astronomy, Texas A and M University, College Station, TX 77843 (United States)

2017-01-01

We perform the first spatially resolved stellar population study of galaxies in the early universe ( z = 3.5–6.5), utilizing the Hubble Space Telescope Cosmic Assembly Near-infrared Deep Extragalactic Legacy Survey imaging data set over the GOODS-S field. We select a sample of 418 bright and extended galaxies at z  = 3.5–6.5 from a parent sample of ∼8000 photometric-redshift-selected galaxies from Finkelstein et al. We first examine galaxies at 3.5 ≲ z ≲ 4.0 using additional deep K -band survey data from the HAWK-I UDS and GOODS Survey which covers the 4000 Å break at these redshifts. We measure the stellar mass, star formation rate, and dust extinction for galaxy inner and outer regions via spatially resolved spectral energy distribution fitting based on a Markov Chain Monte Carlo algorithm. By comparing specific star formation rates (sSFRs) between inner and outer parts of the galaxies we find that the majority of galaxies with high central mass densities show evidence for a preferentially lower sSFR in their centers than in their outer regions, indicative of reduced sSFRs in their central regions. We also study galaxies at z ∼ 5 and 6 (here limited to high spatial resolution in the rest-frame ultraviolet only), finding that they show sSFRs which are generally independent of radial distance from the center of the galaxies. This indicates that stars are formed uniformly at all radii in massive galaxies at z  ∼ 5–6, contrary to massive galaxies at z ≲ 4.

The galactic luminous supersoft X-ray source RXJ0925.7-4758 / MR ...

Indian Academy of Sciences (India)

Nandita Prodhani

2018-01-30

Jan 30, 2018 ... White dwarf; luminous supersoft X-ray source; luminosity; absorption edge. PACS Nos 97.80.Jp; 97.10.Ri; 98.35.Mp; 97.80.Fk. 1. Introduction. For the last few decades, Einstein observatory, Roent- gen Satellite (ROSAT), ASCA, CHANDRA, XMM-. Newton, SWIFT, SUZAKU and other ingenious devices.

P1-5: Effect of Luminance Contrast on the Color Selective Responses in the Inferior Temporal Cortex Neurons of the Macaque Monkey

Directory of Open Access Journals (Sweden)

Tomoyuki Namima

2012-10-01

Full Text Available Although the relationship between color signal and luminance signal is an important problem in visual perception, relatively little is known about how the luminance contrast affects the responses of color selective neurons in the visual cortex. In this study, we examined this problem in the inferior temporal (IT of the awake monkey performing a visual fixation task. Single neuron activities were recorded from the anterior and posterior color selective regions in IT cortex (AITC and PITC identified in previous studies where color selective neurons are accumulated. Color stimuli consisted of 28 stimuli that evenly distribute across the gamut of the CRT display defined on the CIE- xychromaticity diagram at two different luminance levels (5 cd/m 2or 20 cd/m 2 and 2 stimuli at white points. The background was maintained at 10 cd/m 2gray. We found that the effect of luminance contrast on the color selectivity was markedly different between AITC and PITC. When we examined the correlation between the responses to the bright stimuli and those to the dark stimuli with the same chromaticity coordinates, most AITC neurons exhibited high correlation whereas many PITC neurons showed no correlation or only weak correlation. In PITC, the effect was specifically large for neutral colors (white, gray, black and for colors with low saturation. These results indicate that the effect of luminance contrast on the color selective responses differs across different areas and suggest that the separation between color signal and luminance signal involves a higher stage of the cortical color processing.

Investigation of the status quo of massive blood transfusion in China and a synopsis of the proposed guidelines for massive blood transfusion.

Science.gov (United States)

Yang, Jiang-Cun; Wang, Qiu-Shi; Dang, Qian-Li; Sun, Yang; Xu, Cui-Xiang; Jin, Zhan-Kui; Ma, Ting; Liu, Jing

2017-08-01

The aim of this study was to provide an overview of massive transfusion in Chinese hospitals, identify the important indications for massive transfusion and corrective therapies based on clinical evidence and supporting experimental studies, and propose guidelines for the management of massive transfusion. This multiregion, multicenter retrospective study involved a Massive Blood Transfusion Coordination Group composed of 50 clinical experts specializing in blood transfusion, cardiac surgery, anesthesiology, obstetrics, general surgery, and medical statistics from 20 tertiary general hospitals across 5 regions in China. Data were collected for all patients who received ≥10 U red blood cell transfusion within 24 hours in the participating hospitals from January 1 2009 to December 31 2010, including patient demographics, pre-, peri-, and post-operative clinical characteristics, laboratory test results before, during, and after transfusion, and patient mortality at post-transfusion and discharge. We also designed an in vitro hemodilution model to investigate the changes of blood coagulation indices during massive transfusion and the correction of coagulopathy through supplement blood components under different hemodilutions. The experimental data in combination with the clinical evidence were used to determine the optimal proportion and timing for blood component supplementation during massive transfusion. Based on the findings from the present study, together with an extensive review of domestic and international transfusion-related literature and consensus feedback from the 50 experts, we drafted the guidelines on massive blood transfusion that will help Chinese hospitals to develop standardized protocols for massive blood transfusion.

Exploratory X-ray monitoring of luminous radio-quiet quasars at high redshift: Initial results

Energy Technology Data Exchange (ETDEWEB)

Shemmer, Ohad; Stein, Matthew S. [Department of Physics, University of North Texas, Denton, TX 76203 (United States); Brandt, W. N.; Schneider, Donald P. [Department of Astronomy and Astrophysics, The Pennsylvania State University, University Park, PA 16802 (United States); Paolillo, Maurizio [Dipartimento di Scienze Fisiche, Università Federico II di Napoli, via Cinthia 6, I-80126 Napoli (Italy); Kaspi, Shai [School of Physics and Astronomy and the Wise Observatory, Tel Aviv University, Tel Aviv 69978 (Israel); Vignali, Cristian [Dipartimento di Astronomia, Università degli studi di Bologna, via Ranzani 1, I-40127 Bologna (Italy); Lira, Paulina [Departamento de Astronomia, Universidad de Chile, Camino del Observatorio 1515, Santiago (Chile); Gibson, Robert R., E-mail: ohad@unt.edu [Department of Astronomy, University of Washington, Box 351580, Seattle, WA 98195 (United States)

2014-03-10

We present initial results from an exploratory X-ray monitoring project of two groups of comparably luminous radio-quiet quasars (RQQs). The first consists of four sources at 4.10 ≤ z ≤ 4.35, monitored by Chandra, and the second is a comparison sample of three sources at 1.33 ≤ z ≤ 2.74, monitored by Swift. Together with archival X-ray data, the total rest-frame temporal baseline spans ∼2-4 yr and ∼5-13 yr for the first and second group, respectively. Six of these sources show significant X-ray variability over rest-frame timescales of ∼10{sup 2}-10{sup 3} days; three of these also show significant X-ray variability on rest-frame timescales of ∼1-10 days. The X-ray variability properties of our variable sources are similar to those exhibited by nearby and far less luminous active galactic nuclei (AGNs). While we do not directly detect a trend of increasing X-ray variability with redshift, we do confirm previous reports of luminous AGNs exhibiting X-ray variability above that expected from their luminosities, based on simplistic extrapolation from lower luminosity sources. This result may be attributed to luminous sources at the highest redshifts having relatively high accretion rates. Complementary UV-optical monitoring of our sources shows that variations in their optical-X-ray spectral energy distribution are dominated by the X-ray variations. We confirm previous reports of X-ray spectral variations in one of our sources, HS 1700+6416, but do not detect such variations in any of our other sources in spite of X-ray flux variations of up to a factor of ∼4. This project is designed to provide a basic assessment of the X-ray variability properties of RQQs at the highest accessible redshifts that will serve as a benchmark for more systematic monitoring of such sources with future X-ray missions.

Beyond MACS: A Snapshot Survey of the Most Massive Clusters of Galaxies at z>0.5

Science.gov (United States)

Ebeling, Harald

2017-08-01

Truly massive galaxy clusters play a pivotal role for a wealth of extragalactic and cosmological research topics, and SNAPshot observations of these systems are ideally suited to identify the most promising cluster targets for further, in-depth study. The power of this approach was demonstrated by ACS/WFC3 SNAPshots of X-ray selected MACS and eMACS clusters at z>0.3 obtained by us in previous Cycles (44 of them in all of F606W, F814W, F110W, and F140W). Based on these data, the CLASH MCT program selected 16 out of 25 of their targets to be MACS clusters. Similarly, all but one of the six most powerful cluster lenses selected for in-depth study by the HST Frontier Fields initiative are MACS detections, and so are 16 of the 29 z>0.3 clusters targeted by the RELICS legacy program.We propose to extend our spectacularly successful SNAPshot survey of the most X-ray luminous distant clusters to a redshift-mass regime that is poorly sampled by any other project. Targeting only extremely massive clusters at z>0.5 from the X-ray selected eMACS sample (median velocity dispersion: 1180 km/s), the proposed program will (a) identify the most powerful gravitational telescopes at yet higher redshift for the next generation of in-depth studies of the distant Universe with HST and JWST, (b) provide constraints on the mass distribution within these extreme systems, (c) help improve our understanding of the physical nature of galaxy-galaxy and galaxy-gas interactions in cluster cores, and (d) unveil Balmer Break Galaxies at z 2 and Lyman-break galaxies at z>6 as F814W dropouts.Acknowledging the broad community interest in our sample we waive our data rights for these observations.

Luminous flux improvement of xenon fluorescent lamps by applying synchronized high-voltage pulse to the auxiliary external electrode

Energy Technology Data Exchange (ETDEWEB)

Motomura, Hideki; Oka, Kojiro; Sogabe, Toru; Jinno, Masafumi, E-mail: hmoto@mayu.ee.ehime-u.ac.jp [Department of Electrical and Electronic Engineering, Ehime University 3 Bunkyo-cho, Matsuyama, Ehime 790-8577 (Japan)

2011-06-08

As the environmental awareness of people becomes stronger, the demand for mercury-free light sources also becomes stronger. The authors have been developing cold cathode fluorescent lamps in which xenon gas is filled as an ultraviolet radiator instead of mercury. Previously the authors reported the luminous flux enhancement method using a grounded auxiliary external electrode (AEE). In this paper, in order to improve the luminous flux much more, a positive voltage pulse which was synchronized to the main driving negative voltage pulse was applied to the AEE. As a result, the maximum input power increased under which the positive column did not constrict and the luminous flux improved by 70% at the xenon filling pressure of 6.7 kPa. It is proved that the positive voltage pulse application to the AEE with the amplitude of more than 2 kV expands the positive column in the radial direction. It is attributed to the phenomenon that the residual ions and electrons, which are generated by dielectric barrier discharge between the AEE and the anode during the falling edge of the negative pulse to the cathode, spread the discharge path from the anode towards the AEE during the cold cathode discharge mode. By increasing the xenon filling pressure, luminous efficacy was improved to 25 lm W{sup -1}.

Investigating a multigene prognostic assay based on significant pathways for Luminal A breast cancer through gene expression profile analysis.

Science.gov (United States)

Gao, Haiyan; Yang, Mei; Zhang, Xiaolan

2018-04-01

The present study aimed to investigate potential recurrence-risk biomarkers based on significant pathways for Luminal A breast cancer through gene expression profile analysis. Initially, the gene expression profiles of Luminal A breast cancer patients were downloaded from The Cancer Genome Atlas database. The differentially expressed genes (DEGs) were identified using a Limma package and the hierarchical clustering analysis was conducted for the DEGs. In addition, the functional pathways were screened using Kyoto Encyclopedia of Genes and Genomes pathway enrichment analyses and rank ratio calculation. The multigene prognostic assay was exploited based on the statistically significant pathways and its prognostic function was tested using train set and verified using the gene expression data and survival data of Luminal A breast cancer patients downloaded from the Gene Expression Omnibus. A total of 300 DEGs were identified between good and poor outcome groups, including 176 upregulated genes and 124 downregulated genes. The DEGs may be used to effectively distinguish Luminal A samples with different prognoses verified by hierarchical clustering analysis. There were 9 pathways screened as significant pathways and a total of 18 DEGs involved in these 9 pathways were identified as prognostic biomarkers. According to the survival analysis and receiver operating characteristic curve, the obtained 18-gene prognostic assay exhibited good prognostic function with high sensitivity and specificity to both the train and test samples. In conclusion the 18-gene prognostic assay including the key genes, transcription factor 7-like 2, anterior parietal cortex and lymphocyte enhancer factor-1 may provide a new method for predicting outcomes and may be conducive to the promotion of precision medicine for Luminal A breast cancer.

High-mobility group box 1 released by autophagic cancer-associated fibroblasts maintains the stemness of luminal breast cancer cells.

Science.gov (United States)

Zhao, Xi-Long; Lin, Yong; Jiang, Jun; Tang, Zhuo; Yang, Shuai; Lu, Lu; Liang, Yan; Liu, Xue; Tan, Jiao; Hu, Xu-Gang; Niu, Qin; Fu, Wen-Juan; Yan, Ze-Xuan; Guo, De-Yu; Ping, Yi-Fang; Wang, Ji Ming; Zhang, Xia; Kung, Hsiang-Fu; Bian, Xiu-Wu; Yao, Xiao-Hong

2017-11-01

Cancer stem cells/cancer-initiating cells (CICs) and their microenvironmental niche play a vital role in malignant tumour recurrence and metastasis. Cancer-associated fibroblasts (CAFs) are major components of the niche of breast cancer-initiating cells (BCICs), and their interactions may profoundly affect breast cancer progression. Autophagy has been considered to be a critical process for CIC maintenance, but whether it is involved in the cross-talk between CAFs and CICs to affect tumourigenesis and pathological significance has not been determined. In this study, we found that the presence of CAFs containing high levels of microtubule-associated protein 1 light chain 3 (LC3II), a marker of autophagosomes, was associated with more aggressive luminal human breast cancer. CAFs in human luminal breast cancer tissues with high autophagy activity enriched BCICs with increased tumourigenicity. Mechanistically, autophagic CAFs released high-mobility group box 1 (HMGB1), which activated its receptor, Toll-like receptor (TLR) 4, expressed by luminal breast cancer cells, to enhance their stemness and tumourigenicity. Furthermore, immunohistochemistry of 180 luminal breast cancers revealed that high LC3II/TLR4 levels predicted an increased relapse rate and a poorer prognosis. Our findings demonstrate that autophagic CAFs play a critical role in promoting the progression of luminal breast cancer through an HMGB1-TLR4 axis, and that both autophagy in CAFs and TLR4 on breast cancer cells constitute potential therapeutic targets. Copyright © 2017 Pathological Society of Great Britain and Ireland. Published by John Wiley & Sons, Ltd. Copyright © 2017 Pathological Society of Great Britain and Ireland. Published by John Wiley & Sons, Ltd.

Management of massive haemoptysis | Adegboye | Nigerian Journal ...

African Journals Online (AJOL)

Background: This study compares two management techniques in the treatment of massive haemotysis. Method: All patients with massive haemoptysis treated between January 1969 and December 1980 (group 1) were retrospectively reviewed and those prospectively treated between January 1981 and August 1999 ...

Topologically massive gravity and Ricci-Cotton flow

Energy Technology Data Exchange (ETDEWEB)

Lashkari, Nima; Maloney, Alexander, E-mail: lashkari@physics.mcgill.ca, E-mail: maloney@physics.mcgill.ca [McGill Physics Department, 3600 rue University, Montreal, QC H3A 2T8 (Canada)

2011-05-21

We consider topologically massive gravity (TMG), which is three-dimensional general relativity with a cosmological constant and a gravitational Chern-Simons term. When the cosmological constant is negative the theory has two potential vacuum solutions: anti-de Sitter space and warped anti-de Sitter space. The theory also contains a massive graviton state which renders these solutions unstable for certain values of the parameters and boundary conditions. We study the decay of these solutions due to the condensation of the massive graviton mode using Ricci-Cotton flow, which is the appropriate generalization of Ricci flow to TMG. When the Chern-Simons coupling is small the AdS solution flows to warped AdS by the condensation of the massive graviton mode. When the coupling is large the situation is reversed, and warped AdS flows to AdS. Minisuperspace models are constructed where these flows are studied explicitly.

Topologically massive gravity and Ricci-Cotton flow

International Nuclear Information System (INIS)

Lashkari, Nima; Maloney, Alexander

2011-01-01

We consider topologically massive gravity (TMG), which is three-dimensional general relativity with a cosmological constant and a gravitational Chern-Simons term. When the cosmological constant is negative the theory has two potential vacuum solutions: anti-de Sitter space and warped anti-de Sitter space. The theory also contains a massive graviton state which renders these solutions unstable for certain values of the parameters and boundary conditions. We study the decay of these solutions due to the condensation of the massive graviton mode using Ricci-Cotton flow, which is the appropriate generalization of Ricci flow to TMG. When the Chern-Simons coupling is small the AdS solution flows to warped AdS by the condensation of the massive graviton mode. When the coupling is large the situation is reversed, and warped AdS flows to AdS. Minisuperspace models are constructed where these flows are studied explicitly.

Coating with luminal gut-constituents alters adherence of nanoparticles to intestinal epithelial cells

Directory of Open Access Journals (Sweden)

Heike Sinnecker

2014-12-01

Full Text Available Background: Anthropogenic nanoparticles (NPs have found their way into many goods of everyday life. Inhalation, ingestion and skin contact are potential routes for NPs to enter the body. In particular the digestive tract with its huge absorptive surface area provides a prime gateway for NP uptake. Considering that NPs are covered by luminal gut-constituents en route through the gastrointestinal tract, we wanted to know if such modifications have an influence on the interaction between NPs and enterocytes.Results: We investigated the consequences of a treatment with various luminal gut-constituents on the adherence of nanoparticles to intestinal epithelial cells. Carboxylated polystyrene particles 20, 100 and 200 nm in size represented our anthropogenic NPs, and differentiated Caco-2 cells served as model for mature enterocytes of the small intestine. Pretreatment with the proteins BSA and casein consistently reduced the adherence of all NPs to the cultured enterocytes, while incubation of NPs with meat extract had no obvious effect on particle adherence. In contrast, contact with intestinal fluid appeared to increase the particle-cell interaction of 20 and 100 nm NPs.Conclusion: Luminal gut-constituents may both attenuate and augment the adherence of NPs to cell surfaces. These effects appear to be dependent on the particle size as well as on the type of interacting protein. While some proteins will rather passivate particles towards cell attachment, possibly by increasing colloid stability or camouflaging attachment sites, certain components of intestinal fluid are capable to modify particle surfaces in such a way that interactions with cellular surface structures result in an increased binding.

Neutron stars structure in the context of massive gravity

Energy Technology Data Exchange (ETDEWEB)

Hendi, S.H.; Bordbar, G.H.; Panah, B. Eslam; Panahiyan, S., E-mail: hendi@shirazu.ac.ir, E-mail: ghbordbar@shirazu.ac.ir, E-mail: behzad.eslampanah@gmail.com, E-mail: sh.panahiyan@gmail.com [Physics Department and Biruni Observatory, College of Sciences, Shiraz University, Shiraz 71454 (Iran, Islamic Republic of)

2017-07-01

Motivated by the recent interests in spin−2 massive gravitons, we study the structure of neutron star in the context of massive gravity. The modifications of TOV equation in the presence of massive gravity are explored in 4 and higher dimensions. Next, by considering the modern equation of state for the neutron star matter (which is extracted by the lowest order constrained variational (LOCV) method with the AV18 potential), different physical properties of the neutron star (such as Le Chatelier's principle, stability and energy conditions) are investigated. It is shown that consideration of the massive gravity has specific contributions into the structure of neutron star and introduces new prescriptions for the massive astrophysical objects. The mass-radius relation is examined and the effects of massive gravity on the Schwarzschild radius, average density, compactness, gravitational redshift and dynamical stability are studied. Finally, a relation between mass and radius of neutron star versus the Planck mass is extracted.

Neutron stars structure in the context of massive gravity

Science.gov (United States)

Hendi, S. H.; Bordbar, G. H.; Eslam Panah, B.; Panahiyan, S.

2017-07-01

Motivated by the recent interests in spin-2 massive gravitons, we study the structure of neutron star in the context of massive gravity. The modifications of TOV equation in the presence of massive gravity are explored in 4 and higher dimensions. Next, by considering the modern equation of state for the neutron star matter (which is extracted by the lowest order constrained variational (LOCV) method with the AV18 potential), different physical properties of the neutron star (such as Le Chatelier's principle, stability and energy conditions) are investigated. It is shown that consideration of the massive gravity has specific contributions into the structure of neutron star and introduces new prescriptions for the massive astrophysical objects. The mass-radius relation is examined and the effects of massive gravity on the Schwarzschild radius, average density, compactness, gravitational redshift and dynamical stability are studied. Finally, a relation between mass and radius of neutron star versus the Planck mass is extracted.

Neutron stars structure in the context of massive gravity

International Nuclear Information System (INIS)

Hendi, S.H.; Bordbar, G.H.; Panah, B. Eslam; Panahiyan, S.

2017-01-01

Motivated by the recent interests in spin−2 massive gravitons, we study the structure of neutron star in the context of massive gravity. The modifications of TOV equation in the presence of massive gravity are explored in 4 and higher dimensions. Next, by considering the modern equation of state for the neutron star matter (which is extracted by the lowest order constrained variational (LOCV) method with the AV18 potential), different physical properties of the neutron star (such as Le Chatelier's principle, stability and energy conditions) are investigated. It is shown that consideration of the massive gravity has specific contributions into the structure of neutron star and introduces new prescriptions for the massive astrophysical objects. The mass-radius relation is examined and the effects of massive gravity on the Schwarzschild radius, average density, compactness, gravitational redshift and dynamical stability are studied. Finally, a relation between mass and radius of neutron star versus the Planck mass is extracted.

Permutations of massive vacua

Energy Technology Data Exchange (ETDEWEB)

Bourget, Antoine [Department of Physics, Universidad de Oviedo, Avenida Calvo Sotelo 18, 33007 Oviedo (Spain); Troost, Jan [Laboratoire de Physique Théorique de l’É cole Normale Supérieure, CNRS,PSL Research University, Sorbonne Universités, 75005 Paris (France)

2017-05-09

We discuss the permutation group G of massive vacua of four-dimensional gauge theories with N=1 supersymmetry that arises upon tracing loops in the space of couplings. We concentrate on superconformal N=4 and N=2 theories with N=1 supersymmetry preserving mass deformations. The permutation group G of massive vacua is the Galois group of characteristic polynomials for the vacuum expectation values of chiral observables. We provide various techniques to effectively compute characteristic polynomials in given theories, and we deduce the existence of varying symmetry breaking patterns of the duality group depending on the gauge algebra and matter content of the theory. Our examples give rise to interesting field extensions of spaces of modular forms.

Massive stars in galaxies

International Nuclear Information System (INIS)

Humphreys, R.M.

1987-01-01

The relationship between the morphologic type of a galaxy and the evolution of its massive stars is explored, reviewing observational results for nearby galaxies. The data are presented in diagrams, and it is found that the massive-star populations of most Sc spiral galaxies and irregular galaxies are similar, while those of Sb spirals such as M 31 and M 81 may be affected by morphology (via differences in the initial mass function or star-formation rate). Consideration is also given to the stability-related upper luminosity limit in the H-R diagram of hypergiant stars (attributed to radiation pressure in hot stars and turbulence in cool stars) and the goals of future observation campaigns. 88 references

High-Risk Premenopausal Luminal A Breast Cancer Patients Derive no Benefit from Adjuvant Cyclophosphamide-based Chemotherapy: Results from the DBCG77B Clinical Trial.

Science.gov (United States)

Nielsen, Torsten O; Jensen, Maj-Brit; Burugu, Samantha; Gao, Dongxia; Jørgensen, Charlotte L Tykjaer; Balslev, Eva; Ejlertsen, Bent

2017-02-15

Purpose: Luminal A breast cancers have better prognosis than other molecular subtypes. Luminal A cancers may also be insensitive to adjuvant chemotherapy, although there is little high-level evidence to confirm this concept. The primary hypothesis in this formal prospective-retrospective analysis was to assess interaction between subtype (Luminal A vs. other) and treatment (chemotherapy vs. not) for the primary endpoint (10-year invasive disease-free survival) of a breast cancer trial randomizing women to adjuvant chemotherapy, analyzed in multivariate Cox proportional hazards models using the Wald interaction test. Experimental Design: The Danish Breast Cancer Cooperative Group 77B clinical trial randomized 1,072 premenopausal women to no systematic treatment (control), levamisole, cyclophosphamide, or cyclophosphamide-methotrexate-fluorouracil arms. All arms included radiotherapy but no endocrine therapy. Researchers with no access to clinical data performed intrinsic subtype analysis on tissue microarrays using published immunohistochemical methods based on estrogen receptor, progesterone receptor, HER2, Ki67, and basal markers. Results: Patients ( n = 709) had tissue available; chemotherapy benefit in these patients was similar to the original trial (HR, 0.56). Immunohistochemistry classified 165 as Luminal A, 319 Luminal B, 58 HER2-enriched, and 82 core basal (among 91 triple-negative). Patients with Luminal A breast tumors did not benefit from chemotherapy [HR, 1.06; 95% confidence interval (CI), 0.53-2.14; P = 0.86], whereas patients with non-luminal A subtypes did (HR, 0.50; 95% CI, 0.38-0.66; P benefit from adjuvant cyclophosphamide-based chemotherapy. Clin Cancer Res; 23(4); 946-53. ©2016 AACR . ©2016 American Association for Cancer Research.

Timing the formation and assembly of early-type galaxies via spatially resolved stellar populations analysis

Science.gov (United States)

Martín-Navarro, Ignacio; Vazdekis, Alexandre; Falcón-Barroso, Jesús; La Barbera, Francesco; Yıldırım, Akın; van de Ven, Glenn

2018-04-01

To investigate star formation and assembly processes of massive galaxies, we present here a spatially resolved stellar population analysis of a sample of 45 elliptical galaxies (Es) selected from the Calar Alto Legacy Integral Field Area survey. We find rather flat age and [Mg/Fe] radial gradients, weakly dependent on the effective velocity dispersion of the galaxy within half-light radius. However, our analysis shows that metallicity gradients become steeper with increasing galaxy velocity dispersion. In addition, we have homogeneously compared the stellar population gradients of our sample of Es to a sample of nearby relic galaxies, i.e. local remnants of the high-z population of red nuggets. This comparison indicates that, first, the cores of present-day massive galaxies were likely formed in gas-rich, rapid star formation events at high redshift (z ≳ 2). This led to radial metallicity variations steeper than observed in the local Universe, and positive [Mg/Fe] gradients. Secondly, our analysis also suggests that a later sequence of minor dry mergers, populating the outskirts of early-type galaxies (ETGs), flattened the pristine [Mg/Fe] and metallicity gradients. Finally, we find a tight age-[Mg/Fe] relation, supporting that the duration of the star formation is the main driver of the [Mg/Fe] enhancement in massive ETGs. However, the star formation time-scale alone is not able to fully explain our [Mg/Fe] measurements. Interestingly, our results match the expected effect that a variable stellar initial mass function would have on the [Mg/Fe] ratio.

Nitrogen chronology of massive main sequence stars

NARCIS (Netherlands)

Köhler, K.; Borzyszkowski, M.; Brott, I.; Langer, N.; de Koter, A.

2012-01-01

Context. Rotational mixing in massive main sequence stars is predicted to monotonically increase their surface nitrogen abundance with time. Aims. We use this effect to design a method for constraining the age and the inclination angle of massive main sequence stars, given their observed luminosity,

Major merging history in CANDELS. I. Evolution of the incidence of massive galaxy-galaxy pairs from z = 3 to z ˜ 0

Science.gov (United States)

Mantha, Kameswara Bharadwaj; McIntosh, Daniel H.; Brennan, Ryan; Ferguson, Henry C.; Kodra, Dritan; Newman, Jeffrey A.; Rafelski, Marc; Somerville, Rachel S.; Conselice, Christopher J.; Cook, Joshua S.; Hathi, Nimish P.; Koo, David C.; Lotz, Jennifer M.; Simmons, Brooke D.; Straughn, Amber N.; Snyder, Gregory F.; Wuyts, Stijn; Bell, Eric F.; Dekel, Avishai; Kartaltepe, Jeyhan; Kocevski, Dale D.; Koekemoer, Anton M.; Lee, Seong-Kook; Lucas, Ray A.; Pacifici, Camilla; Peth, Michael A.; Barro, Guillermo; Dahlen, Tomas; Finkelstein, Steven L.; Fontana, Adriano; Galametz, Audrey; Grogin, Norman A.; Guo, Yicheng; Mobasher, Bahram; Nayyeri, Hooshang; Pérez-González, Pablo G.; Pforr, Janine; Santini, Paola; Stefanon, Mauro; Wiklind, Tommy

2018-04-01

The rate of major galaxy-galaxy merging is theoretically predicted to steadily increase with redshift during the peak epoch of massive galaxy development (1 ≤ z ≤ 3). We use close-pair statistics to objectively study the incidence of massive galaxies (stellar M1 > 2 × 1010 M⊙) hosting major companions (1 ≤ M1/M2 ≤ 4; i.e. 4:1) companions at z > 1. We show that these evolutionary trends are statistically robust to changes in companion proximity. We find disagreements between published results are resolved when selection criteria are closely matched. If we compute merger rates using constant fraction-to-rate conversion factors (Cmerg,pair = 0.6 and Tobs,pair = 0.65 Gyr), we find that MR rates disagree with theoretical predictions at z > 1.5. Instead, if we use an evolving Tobs,pair(z) ∝ (1 + z)-2 from Snyder et al., our MR-based rates agree with theory at 0 history.

Using massive digital libraries a LITA guide

CERN Document Server

Weiss, Andrew

2014-01-01

Some have viewed the ascendance of the digital library as some kind of existential apocalypse, nothing less than the beginning of the end for the traditional library. But Weiss, recognizing the concept of the library as a ""big idea"" that has been implemented in many ways over thousands of years, is not so gloomy. In this thought-provoking and unabashedly optimistic book, he explores how massive digital libraries are already adapting to society's needs, and looks ahead to the massive digital libraries of tomorrow, coveringThe author's criteria for defining massive digital librariesA history o

Two-dimensional thermofield bosonization II: Massive fermions

International Nuclear Information System (INIS)

Amaral, R.L.P.G.; Belvedere, L.V.; Rothe, K.D.

2008-01-01

We consider the perturbative computation of the N-point function of chiral densities of massive free fermions at finite temperature within the thermofield dynamics approach. The infinite series in the mass parameter for the N-point functions are computed in the fermionic formulation and compared with the corresponding perturbative series in the interaction parameter in the bosonized thermofield formulation. Thereby we establish in thermofield dynamics the formal equivalence of the massive free fermion theory with the sine-Gordon thermofield model for a particular value of the sine-Gordon parameter. We extend the thermofield bosonization to include the massive Thirring model

Limiting Accretion onto Massive Stars by Fragmentation-Induced Starvation

Energy Technology Data Exchange (ETDEWEB)

Peters, Thomas; /ZAH, Heidelberg; Klessen, Ralf S.; /ZAH, Heidelberg /KIPAC, Menlo Park; Mac Low, Mordecai-Mark; /Amer. Museum Natural Hist.; Banerjee, Robi; /ZAH, Heidelberg

2010-08-25

Massive stars influence their surroundings through radiation, winds, and supernova explosions far out of proportion to their small numbers. However, the physical processes that initiate and govern the birth of massive stars remain poorly understood. Two widely discussed models are monolithic collapse of molecular cloud cores and competitive accretion. To learn more about massive star formation, we perform simulations of the collapse of rotating, massive, cloud cores including radiative heating by both non-ionizing and ionizing radiation using the FLASH adaptive mesh refinement code. These simulations show fragmentation from gravitational instability in the enormously dense accretion flows required to build up massive stars. Secondary stars form rapidly in these flows and accrete mass that would have otherwise been consumed by the massive star in the center, in a process that we term fragmentation-induced starvation. This explains why massive stars are usually found as members of high-order stellar systems that themselves belong to large clusters containing stars of all masses. The radiative heating does not prevent fragmentation, but does lead to a higher Jeans mass, resulting in fewer and more massive stars than would form without the heating. This mechanism reproduces the observed relation between the total stellar mass in the cluster and the mass of the largest star. It predicts strong clumping and filamentary structure in the center of collapsing cores, as has recently been observed. We speculate that a similar mechanism will act during primordial star formation.

Hunting for a massive neutrino

CERN Document Server

AUTHOR|(CDS)2108802

1997-01-01

A great effort is devoted by many groups of physicists all over the world to give an answer to the following question: Is the neutrino massive ? This question has profound implications with particle physics, astrophysics and cosmology, in relation to the so-called Dark Matter puzzle. The neutrino oscillation process, in particular, can only occur if the neutrino is massive. An overview of the neutrino mass measurements, of the oscillation formalism and experiments will be given, also in connection with the present experimental programme at CERN with the two experiments CHORUS and NOMAD.

On the singularities of massive superstring amplitudes

NARCIS (Netherlands)

Foda, O.

1987-01-01

Superstring one-loop amplitudes with massive external states are shown to be in general ill-defined due to internal on-shell propagators. However, we argue that since any massive string state (in the uncompactified theory) has a finite lifetime to decay into massless particles, such amplitudes are

Psychophysical Measurements of Luminance Contrast Sensitivity and Color Discrimination with Transparent and Blue-Light Filter Intraocular Lenses.

Science.gov (United States)

da Costa, Marcelo Fernandes; Júnior, Augusto Paranhos; Lottenberg, Claudio Luiz; Castro, Leonardo Cunha; Ventura, Dora Fix

2017-12-01

The purpose of this study was to measure luminance contrast sensitivity and color vision thresholdfs in normal subjects using a blue light filter lens and transparent intraocular lens material. Monocular luminance grating contrast sensitivity was measured with Psycho for Windows (version 2.36; Cambridge Research Systems) at 3.0, 6.0, 12.0, 20.0, and 30.0 cycles per degree of visual angle (cpd) in 15 normal subjects (eight female), with a mean age of 21.6 years (SD = 3.8 years). Chromatic discrimination was assessed with the Cambridge colour test (CCT) along the protan, deutan, and tritan color confusion axes. Both tests were performed in a darkened room under two situations: with a transparent lens and with blue light filter lens. Subjective impressions were taken by subjects regarding their visual experience under both conditions. No difference was found between the luminance contrast sensitivity measured with transparent and blue light filter. However, 13/15 (87%) of the subjects reported more comfortable vision with the blue filter. In the color vision test, tritan thresholds were significantly higher for the blue filter compared with the transparent filter (p = 0.003). For protan and deutan thresholds no differences were found. Blue-yellow color vision is impaired with the blue light filter, and no impairment occurs with the transparent filter. No significant differences in thresholds were found in the luminance contrast sensitivity comparing the blue light and transparent filters. The impact of short wavelength light filtering on intrinsically photosensitive retinal ganglion cells is also discussed.

A Madden-Julian oscillation event realistically simulated by a global cloud-resolving model.

Science.gov (United States)

Miura, Hiroaki; Satoh, Masaki; Nasuno, Tomoe; Noda, Akira T; Oouchi, Kazuyoshi

2007-12-14

A Madden-Julian Oscillation (MJO) is a massive weather event consisting of deep convection coupled with atmospheric circulation, moving slowly eastward over the Indian and Pacific Oceans. Despite its enormous influence on many weather and climate systems worldwide, it has proven very difficult to simulate an MJO because of assumptions about cumulus clouds in global meteorological models. Using a model that allows direct coupling of the atmospheric circulation and clouds, we successfully simulated the slow eastward migration of an MJO event. Topography, the zonal sea surface temperature gradient, and interplay between eastward- and westward-propagating signals controlled the timing of the eastward transition of the convective center. Our results demonstrate the potential making of month-long MJO predictions when global cloud-resolving models with realistic initial conditions are used.

Black holes in massive gravity as heat engines

Science.gov (United States)

Hendi, S. H.; Eslam Panah, B.; Panahiyan, S.; Liu, H.; Meng, X.-H.

2018-06-01

The paper at hand studies the heat engine provided by black holes in the presence of massive gravity. The main motivation is to investigate the effects of massive gravity on different properties of the heat engine. It will be shown that massive gravity parameters modify the efficiency of engine on a significant level. Furthermore, it will be pointed out that it is possible to have a heat engine for non-spherical black holes in massive gravity, and therefore, we will study the effects of horizon topology on the properties of heat engine. Surprisingly, it will be shown that the highest efficiency for the heat engine belongs to black holes with the hyperbolic horizon, while the lowest one belongs to the spherical black holes.

Identification of lncRNA FAM83H-AS1 as a novel prognostic marker in luminal subtype breast cancer

Directory of Open Access Journals (Sweden)

Yang F

2016-11-01

Full Text Available Fan Yang, Shi-Xu Lv, Lin Lv, Ye-Huan Liu, Si-Yang Dong, Zhi-Han Yao, Xuan-xuan Dai, Xiao-Hua Zhang, Ou-Chen Wang Department of Surgical Oncology, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, People’s Republic of China Background: Luminal subtype breast cancer accounts for a predominant number of breast cancers. Considering the heterogeneity of the disease, it is urgent to develop novel biomarkers to improve risk stratification and optimize therapy choices. Long non-coding RNA (lncRNA represents an emerging and understudied class of transcripts that play a significant role in cancer biology. Growing knowledge of cancer-associated lncRNAs contributes to the development of molecular markers for prognosis evaluation and gene therapy.Materials and methods: Three pairs of primary luminal subtype breast cancer tissues and adjacent non-cancerous tissues were collected and sequenced. EBseq algorithm was used to identify differentially expressed lncRNAs. RNA sequencing data from The Cancer Genome Atlas (TCGA database were used to validate the robustness of our RNA-seq results. Kaplan–Meier and Cox regression analyses were utilized to assess the association between the lncRNAs and overall survival of patients in TCGA cohort.Results: A total of 796 lncRNAs were significantly dysregulated in luminal subtype breast cancer, including 436 upregulated and 360 downregulated lncRNAs. Among them, FAM83H antisense RNA 1 (FAM83H-AS1 was the most upregulated lncRNA, whereas GSN antisense RNA 1 (GSN-AS1 was the most downregulated lncRNA. Moreover, we proved that the high expression level of FAM83H-AS1 indicated unfavorable prognosis not only in luminal subtype breast cancer but also in all subtype breast cancers. To the best of our knowledge, this is the first report indicating that FAM83H-AS1 was involved in luminal subtype breast cancer and was an independent prognostic indicator.Conclusion: Our study provides a rich resource

The VLT-FLAMES survey of massive stars

NARCIS (Netherlands)

Evans, C.; Langer, N.; Brott, I.; Hunter, I.; Smartt, S.J.; Lennon, D.J.

2008-01-01

The VLT-FLAMES Survey of Massive Stars was an ESO Large Programme to understand rotational mixing and stellar mass loss in different metallicity environments, in order to better constrain massive star evolution. We gathered high-quality spectra of over 800 stars in the Galaxy and in the Magellanic

Massive cerebellar infarction: a neurosurgical approach

Directory of Open Access Journals (Sweden)

Salazar Luis Rafael Moscote

2015-12-01

Full Text Available Cerebellar infarction is a challenge for the neurosurgeon. The rapid recognition will crucial to avoid devastating consequences. The massive cerebellar infarction has pseudotumoral behavior, should affect at least one third of the volume of the cerebellum. The irrigation of the cerebellum presents anatomical diversity, favoring the appearance of atypical infarcts. The neurosurgical management is critical for massive cerebellar infarction. We present a review of the literature.

A longitudinal study of perceptual grouping by proximity, luminance and shape in infants at two, four and six months

OpenAIRE

Farran, E. K.; Brown, J. H.; Cole, V. L.; Houston-Price, C.; Karmiloff-Smith, A.

2008-01-01

Grouping by luminance and shape similarity has previously been demonstrated in neonates and at 4 months, respectively. By contrast, grouping by proximity has hitherto not been investigated in infancy. This is also the first study to chart the developmental emergence of perceptual grouping longitudinally. Sixty-one infants were presented with a matrix of local stimuli grouped horizontally or vertically by luminance, shape or proximity at 2, 4, and 6 months. Infants were exposed to each set of ...

Kinetics on Demand Is a Simple Mathematical Solution that Fits Recorded Caffeine-Induced Luminal SR Ca2+ Changes in Smooth Muscle Cells.

Directory of Open Access Journals (Sweden)

Norma C Perez-Rosas

Full Text Available The process of Ca2+ release from sarcoplasmic reticulum (SR comprises 4 phases in smooth muscle cells. Phase 1 is characterized by a large increase of the intracellular Ca2+ concentration ([Ca2+]i with a minimal reduction of the free luminal SR [Ca2+] ([Ca2+]FSR. Importantly, active SR Ca2+ ATPases (SERCA pumps are necessary for phase 1 to occur. This situation cannot be explained by the standard kinetics that involves a fixed amount of luminal Ca2+ binding sites. A new mathematical model was developed that assumes an increasing SR Ca2+ buffering capacity in response to an increase of the luminal SR [Ca2+] that is called Kinetics-on-Demand (KonD model. This approach can explain both phase 1 and the refractory period associated with a recovered [Ca2+]FSR. Additionally, our data suggest that active SERCA pumps are a requisite for KonD to be functional; otherwise luminal SR Ca2+ binding proteins switch to standard kinetics. The importance of KonD Ca2+ binding properties is twofold: a more efficient Ca2+ release process and that [Ca2+]FSR and Ca2+-bound to SR proteins ([Ca2+]BSR can be regulated separately allowing for Ca2+ release to occur (provided by Ca2+-bound to luminal Ca2+ binding proteins without an initial reduction of the [Ca2+]FSR.

A modern study of HD 166734: a massive supergiant system

Science.gov (United States)

Mahy, L.; Damerdji, Y.; Gosset, E.; Nitschelm, C.; Eenens, P.; Sana, H.; Klotz, A.

2017-11-01

Aims: HD 166734 is an eccentric eclipsing binary system composed of two supergiant O-type stars, orbiting with a 34.5-day period. In this rare configuration for such stars, the two objects mainly evolve independently, following single-star evolution so far. This system provides a chance to study the individual parameters of two supergiant massive stars and to derive their real masses. Methods: An intensive monitoring was dedicated to HD 166734. We analyzed mid- and high-resolution optical spectra to constrain the orbital parameters of this system. We also studied its light curve for the first time, obtained in the VRI filters. Finally, we disentangled the spectra of the two stars and modeled them with the CMFGEN atmosphere code in order to determine the individual physical parameters. Results: HD 166734 is a O7.5If+O9I(f) binary. We confirm its orbital period but we revise the other orbital parameters. In comparison to what we found in the literature, the system is more eccentric and, now, the hottest and the most luminous component is also the most massive one. The light curve exhibits only one eclipse and its analysis indicates an inclination of 63.0° ± 2.7°. The photometric analysis provides us with a good estimation of the luminosities of the stars, and therefore their exact positions in the Hertzsprung-Russell diagram. The evolutionary and the spectroscopic masses show good agreement with the dynamical masses of 39.5 M⊙ for the primary and 33.5 M⊙ for the secondary, within the uncertainties. The two components are both enriched in helium and in nitrogen and depleted in carbon. In addition, the primary also shows a depletion in oxygen. Their surface abundances are however not different from those derived from single supergiant stars, yielding, for both components, an evolution similar to that of single stars. Based on observations collected at the European Southern Observatory (La Silla, Chile) with FEROS and TAROT and on data collected at the San Pedro

FROM THE CONVERGENCE OF FILAMENTS TO DISK-OUTFLOW ACCRETION: MASSIVE STAR FORMATION IN W33A

International Nuclear Information System (INIS)

Galvan-Madrid, Roberto; Zhang Qizhou; Keto, Eric; Ho, Paul T. P.; Pineda, Jaime E.; Zapata, Luis A.; RodrIguez, Luis F.; Vazquez-Semadeni, Enrique

2010-01-01

Interferometric observations of the W33A massive star formation region, performed with the Submillimeter Array and the Very Large Array at resolutions from 5'' (0.1 pc) to 0.''5 (0.01 pc), are presented. Our three main findings are: (1) parsec-scale, filamentary structures of cold molecular gas are detected. Two filaments at different velocities intersect in the zone where the star formation is occurring. This is consistent with triggering of the star formation activity by the convergence of such filaments, as predicted by numerical simulations of star formation initiated by converging flows. (2) The two dusty cores (MM1 and MM2) at the intersection of the filaments are found to be at different evolutionary stages, and each of them is resolved into multiple condensations. MM1 and MM2 have markedly different temperatures, continuum spectral indices, molecular-line spectra, and masses of both stars and gas. (3) The dynamics of the 'hot-core' MM1 indicates the presence of a rotating disk in its center (MM1-Main) around a faint free-free source. The stellar mass is estimated to be ∼10 M sun . A massive molecular outflow is observed along the rotation axis of the disk.

On massive gravitons in 2+1 dimensions

NARCIS (Netherlands)

Bergshoeff, Eric; Hohm, Olaf; Townsend, Paul; Lazkoz, R; Vera, R

2010-01-01

The Fierz-Pauli (FP) free field theory for massive spin-2 particles can be extended, in a spacetime of (1+2) dimensions (3D), to a generally covariant parity-preserving interacting field theory, in at least two ways. One is "new massive gravity" (NMG), with an action that involves curvature-squared

Shock waves in luminous early-type stars

International Nuclear Information System (INIS)

Castor, J.I.

1986-01-01

Shock waves that occur in stellar atmospheres have their origin in some hydrodynamic instability of the atmosphere itself or of the stellar interior. In luminous early-type stars these two possibilities are represented by shocks due to an unstable radiatively-accelerated wind, and to shocks generated by the non-radial pulsations known to be present in many or most OB stars. This review is concerned with the structure and development of the shocks in these two cases, and especially with the mass loss that may be due specifically to the shocks. Pulsation-produced shocks are found to be very unfavorable for causing mass loss, owing to the great radiation efficiency that allows them to remain isothermal. The situation regarding radiatively-driven shocks remains unclear, awaiting detailed hydrodynamics calculations. 20 refs., 2 figs

Holographic heat engine within the framework of massive gravity

Science.gov (United States)

Mo, Jie-Xiong; Li, Gu-Qiang

2018-05-01

Heat engine models are constructed within the framework of massive gravity in this paper. For the four-dimensional charged black holes in massive gravity, it is shown that the existence of graviton mass improves the heat engine efficiency significantly. The situation is more complicated for the five-dimensional neutral black holes since the constant which corresponds to the third massive potential also contributes to the efficiency. It is also shown that the existence of graviton mass can improve the heat engine efficiency. Moreover, we probe how the massive gravity influences the behavior of the heat engine efficiency approaching the Carnot efficiency.

THE 100 Myr STAR FORMATION HISTORY OF NGC 5471 FROM CLUSTER AND RESOLVED STELLAR PHOTOMETRY

International Nuclear Information System (INIS)

Garcia-Benito, Ruben; Perez, Enrique; Maiz Apellaniz, Jesus; Cervino, Miguel; Diaz, Angeles I.

2011-01-01

We show that star formation in the giant H II region NGC 5471 has been ongoing during the past 100 Myr. Using Hubble Space Telescope/Wide-Field Planetary Camera 2 F547M and F675W, ground-based JHK s , and GALEX FUV and NUV images, we have conducted a photometric study of the star formation history (SFH) in the massive giant extragalactic H II region NGC 5471 in M101. We perform a photometric study of the color-magnitude diagram (CMD) of the resolved stars and an integrated analysis of the main individual star-forming clusters and of NGC 5471 as a whole. The integrated UV-optical-NIR photometry for the whole region provides two different reference ages, 8 Myr and 60 Myr, revealing a complex SFH, clearly confirmed by the CMD-resolved stellar photometry analysis. The spatial distribution of the stars shows that the star formation in NGC 5471 has proceeded along the whole region during, at least, the last 100 Myr. The current ionizing clusters are enclosed within a large bubble, which is likely to have been produced by the stars that formed in a major event ∼20 Myr ago.

Chandra X-ray observations of the hyper-luminous infrared galaxy IRAS F15307+3252

Science.gov (United States)

Hlavacek-Larrondo, J.; Gandhi, P.; Hogan, M. T.; Gendron-Marsolais, M.-L.; Edge, A. C.; Fabian, A. C.; Russell, H. R.; Iwasawa, K.; Mezcua, M.

2017-01-01

Hyper-luminous infrared galaxies (HyLIRGs) lie at the extreme luminosity end of the IR galaxy population with LIR > 1013 L⊙. They are thought to be closer counterparts of the more distant sub-millimeter galaxies, and should therefore be optimal targets to study the most massive systems in formation. We present deep Chandra observations of IRAS F15307+3252 (100 ks), a classical HyLIRG located at z = 0.93 and hosting a radio-loud AGN (L1.4 GHz ˜ 3.5 × 1025 W Hz-1). The Chandra images reveal the presence of extended (r = 160 kpc), asymmetric X-ray emission in the soft 0.3-2.0 keV band that has no radio counterpart. We therefore argue that the emission is of thermal origin originating from a hot intragroup or intracluster medium virializing in the potential. We find that the temperature (˜2 keV) and bolometric X-ray luminosity (˜3 × 1043 erg s-1) of the gas follow the expected LX-ray-T correlation for groups and clusters, and that the gas has a remarkably short cooling time of 1.2 Gyr. In addition, VLA radio observations reveal that the galaxy hosts an unresolved compact steep-spectrum (CSS) source, most likely indicating the presence of a young radio source similar to 3C186. We also confirm that the nucleus is dominated by a redshifted 6.4 keV Fe Kα line, strongly suggesting that the AGN is Compton-thick. Finally, Hubble images reveal an overdensity of galaxies and sub-structure in the galaxy that correlates with soft X-ray emission. This could be a snapshot view of on-going groupings expected in a growing cluster environment. IRAS F15307+3252 might therefore be a rare example of a group in the process of transforming into a cluster.

Formation of Massive Molecular Cloud Cores by Cloud-cloud Collision

OpenAIRE

Inoue, Tsuyoshi; Fukui, Yasuo

2013-01-01

Recent observations of molecular clouds around rich massive star clusters including NGC3603, Westerlund 2, and M20 revealed that the formation of massive stars could be triggered by a cloud-cloud collision. By using three-dimensional, isothermal, magnetohydrodynamics simulations with the effect of self-gravity, we demonstrate that massive, gravitationally unstable, molecular cloud cores are formed behind the strong shock waves induced by the cloud-cloud collision. We find that the massive mol...

Identification of New Epididymal Luminal Fluid Proteins Involved in Sperm Maturation in Infertile Rats Treated by Dutasteride Using iTRAQ

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Shu-Wu Xie

2016-05-01

Full Text Available Background: Spermatozoa become mature and acquire fertilizing capacity during their passage through the epididymal lumen. In this study, we identified new epididymal luminal fluid proteins involved in sperm maturation in infertile rats by dutasteride, a dual 5α-reductase inhibitor, in order to provide potential epididymal targets for new contraceptives and infertility treatment. Methods: Male rats were treated with dutasteride for 28 consecutive days. We observed the protein expression profiles in the epididymal luminal fluids in infertile and normal rats using isobaric tags for relative and absolute quantitation (iTRAQ technique. The confidence of proteome data was validated by enzyme-linked immunosorbent assays. Results: 1045 proteins were tested, and 23 of them presented different expression profiling in the infertile and normal rats. The seven proteins were down-regulated, and 16 proteins were up-regulated. Among the seven proteins which were significantly down-regulated by dutasteride in the epididymal luminal fluids, there were three β-defensins (Defb2, Defb18 and Defb39, which maybe the key proteins involved in epididymal sperm maturation and male fertility. Conclusions: We report for the first time that dutasteride influences the protein expression profiling in the epididymal luminal fluids of rats, and this result provides some new epididymal targets for male contraception and infertility therapy.

Upper Limits on the Presence of Central Massive Black Holes in Two Ultra-compact Dwarf Galaxies in Centaurus A

Science.gov (United States)

Voggel, Karina T.; Seth, Anil C.; Neumayer, Nadine; Mieske, Steffen; Chilingarian, Igor; Ahn, Christopher; Baumgardt, Holger; Hilker, Michael; Nguyen, Dieu D.; Romanowsky, Aaron J.; Walsh, Jonelle L.; den Brok, Mark; Strader, Jay

2018-05-01

The recent discovery of massive black holes (BHs) in the centers of high-mass ultra-compact dwarf galaxies (UCDs) suggests that at least some are the stripped nuclear star clusters of dwarf galaxies. We present the first study that investigates whether such massive BHs, and therefore stripped nuclei, also exist in low-mass (M < 107 M ⊙) UCDs. We constrain the BH masses of two UCDs located in Centaurus A (UCD 320 and UCD 330) using Jeans modeling of the resolved stellar kinematics from adaptive optics data obtained with the SINFONI integral field spectrograph at the Very Large Telescope (VLT/SINFONI). No massive BHs are found in either UCD. We find a 3σ upper limit on the central BH mass in UCD 330 of M • < 1.0 × 105 M ⊙, which corresponds to 1.7% of the total mass. This excludes a high-mass fraction BH and would only allow low-mass BHs similar to those claimed to be detected in Local Group globular clusters. For UCD 320, poorer data quality results in a less constraining 3σ upper limit of M • < 1 × 106 M ⊙, which is equal to 37.7% of the total mass. The dynamical mass-to-light ratios of UCD 320 and UCD 330 are not inflated compared to predictions from stellar population models. The non-detection of BHs in these low-mass UCDs is consistent with the idea that elevated dynamical mass-to-light ratios do indicate the presence of a substantial BH. Although no massive BHs are detected, these systems could still be stripped nuclei. The strong rotation (v/σ of 0.3–0.4) in both UCDs and the two-component light profile in UCD 330 support the idea that these UCDs may be stripped nuclei of low-mass galaxies whose BH occupation fraction is not yet known.

Massively Parallel Algorithms for Solution of Schrodinger Equation

Science.gov (United States)

Fijany, Amir; Barhen, Jacob; Toomerian, Nikzad

1994-01-01

In this paper massively parallel algorithms for solution of Schrodinger equation are developed. Our results clearly indicate that the Crank-Nicolson method, in addition to its excellent numerical properties, is also highly suitable for massively parallel computation.

Intelligent Luminance Control of Lighting Systems Based on Imaging Sensor Feedback

Directory of Open Access Journals (Sweden)

Haoting Liu

2017-02-01

Full Text Available An imaging sensor-based intelligent Light Emitting Diode (LED lighting system for desk use is proposed. In contrast to the traditional intelligent lighting system, such as the photosensitive resistance sensor-based or the infrared sensor-based system, the imaging sensor can realize a finer perception of the environmental light; thus it can guide a more precise lighting control. Before this system works, first lots of typical imaging lighting data of the desk application are accumulated. Second, a series of subjective and objective Lighting Effect Evaluation Metrics (LEEMs are defined and assessed for these datasets above. Then the cluster benchmarks of these objective LEEMs can be obtained. Third, both a single LEEM-based control and a multiple LEEMs-based control are developed to realize a kind of optimal luminance tuning. When this system works, first it captures the lighting image using a wearable camera. Then it computes the objective LEEMs of the captured image and compares them with the cluster benchmarks of the objective LEEMs. Finally, the single LEEM-based or the multiple LEEMs-based control can be implemented to get a kind of optimal lighting effect. Many experiment results have shown the proposed system can tune the LED lamp automatically according to environment luminance changes.

Critical N = (1, 1) general massive supergravity

Science.gov (United States)

Deger, Nihat Sadik; Moutsopoulos, George; Rosseel, Jan

2018-04-01

In this paper we study the supermultiplet structure of N = (1, 1) General Massive Supergravity at non-critical and critical points of its parameter space. To do this, we first linearize the theory around its maximally supersymmetric AdS3 vacuum and obtain the full linearized Lagrangian including fermionic terms. At generic values, linearized modes can be organized as two massless and 2 massive multiplets where supersymmetry relates them in the standard way. At critical points logarithmic modes appear and we find that in three of such points some of the supersymmetry transformations are non-invertible in logarithmic multiplets. However, in the fourth critical point, there is a massive logarithmic multiplet with invertible supersymmetry transformations.

HOW TO FIND YOUNG MASSIVE CLUSTER PROGENITORS

Energy Technology Data Exchange (ETDEWEB)

Bressert, E.; Longmore, S.; Testi, L. [European Southern Observatory, Karl Schwarzschild Str. 2, D-85748 Garching bei Muenchen (Germany); Ginsburg, A.; Bally, J.; Battersby, C. [Center for Astrophysics and Space Astronomy, University of Colorado, Boulder, CO 80309 (United States)

2012-10-20

We propose that bound, young massive stellar clusters form from dense clouds that have escape speeds greater than the sound speed in photo-ionized gas. In these clumps, radiative feedback in the form of gas ionization is bottled up, enabling star formation to proceed to sufficiently high efficiency so that the resulting star cluster remains bound even after gas removal. We estimate the observable properties of the massive proto-clusters (MPCs) for existing Galactic plane surveys and suggest how they may be sought in recent and upcoming extragalactic observations. These surveys will potentially provide a significant sample of MPC candidates that will allow us to better understand extreme star-formation and massive cluster formation in the Local Universe.

Massive type IIA supergravity and E10

International Nuclear Information System (INIS)

Henneaux, M.; Kleinschmidt, A.; Persson, D.; Jamsin, E.

2009-01-01

In this talk we investigate the symmetry under E 10 of Romans' massive type IIA supergravity. We show that the dynamics of a spinning particle in a non-linear sigma model on the coset space E 10 /K(E 10 ) reproduces the bosonic and fermionic dynamics of massive IIA supergravity, in the standard truncation. In particular, we identify Romans' mass with a generator of E 10 that is beyond the realm of the generators of E 10 considered in the eleven-dimensional analysis, but using the same, underformed sigma model. As a consequence, this work provides a dynamical unification of the massless and massive versions of type IIA supergravity inside E 10 . (Abstract Copyright [2009], Wiley Periodicals, Inc.)

Hyper-massive cloud, shock and stellar formation efficiency

International Nuclear Information System (INIS)

Louvet, Fabien

2014-01-01

O and B types stars are of paramount importance in the energy budget of galaxies and play a crucial role enriching the interstellar medium. However, their formation, unlike that of solar-type stars, is still subject to debate, if not an enigma. The earliest stages of massive star formation and the formation of their parent cloud are still crucial astrophysical questions that drew a lot of attention in the community, both from the theoretical and observational perspective, during the last decade. It has been proposed that massive stars are born in massive dense cores that form through very dynamic processes, such as converging flows of gas. During my PhD, I conducted a thorough study of the formation of dense cores and massive stars in the W43-MM1 supermassive structure, located at 6 kpc from the sun. At first, I showed a direct correlation between the star formation efficiency and the volume gas density of molecular clouds, in contrast with scenarios suggested by previous studies. Indeed, the spatial distribution and mass function of the massive dense cores currently forming in W43-MM1 suggests that this supermassive filament is undergoing a star formation burst, increasing as one approaches its center. I compared these observational results with the most recent numerical and analytical models of star formation. This comparison not only provides new constraints on the formation of supermassive filaments, but also suggests that understanding star formation in high density, extreme ridges requires a detailed portrait of the structure of these exceptional objects. Second, having shown that the formation of massive stars depends strongly on the properties of the ridges where they form, I studied the formation processes of these filaments, thanks of the characterization of their global dynamics. Specifically, I used a tracer of shocks (SiO molecule) to disentangle the feedback of local star formation processes (bipolar jets and outflows) from shocks tracing the pristine

Hot spots effect on infrared spectral luminance emitted by carbon under plasma particles impact

International Nuclear Information System (INIS)

Delchambre, E.; Reichle, R.; Mitteau, R.; Missirlian, M.; Gobin, R.

2004-01-01

During the last Tore Supra campaigns, an anomalous deformation in the near infrared spectrum of radiation has been observed on neutralizer underneath the Toroidal Pumped Limiter (TPL) on which we observed the growth of carbon layer. The consequence is the difficulty to asses the surface temperature of the components and the power loaded. Laboratory experiment has been performed, using an Electron Cyclotron Resonance (ECR) ions source, to reproduce, characterize and explain this phenomenon. The luminance emitted by Carbon Fibre Composite (CFC) and pyrolytic graphite, have been observed under 95 keV of H+ bombardments. The amplitude of the deformation was found to depend on the type of material used and the power density of the incident power loaded. This paper presents the possible hot spots explanation. The experimental luminance deformation is reproduced and these results are validated using a thermal model of dust in radiate equilibrium. (authors)

Polarized bow shocks reveal features of the winds and environments of massive stars

Science.gov (United States)

Shrestha, Manisha

2018-01-01

Massive stars strongly affect their surroundings through their energetic stellar winds and deaths as supernovae. The bow shock structures created by fast-moving massive stars contain important information about the winds and ultimate fates of these stars as well as their local interstellar medium (ISM). Since bow shocks are aspherical, the light scattered in the dense shock material becomes polarized. Analyzing this polarization reveals details of the bow shock geometry as well as the composition, velocity, density, and albedo of the scattering material. With these quantities, we can constrain the properties of the stellar wind and thus the evolutionary state of the star, as well as the dust composition of the local ISM.In my dissertation research, I use a Monte Carlo radiative transfer code that I optimized to simulate the polarization signatures produced by both resolved and unresolved stellar wind bow shocks (SWBS) illuminated by a central star and by shock emission. I derive bow shock shapes and densities from published analytical calculations and smooth particle hydrodynamic (SPH) models. In the case of the analytical SWBS and electron scattering, I find that higher optical depths produce higher polarization and position angle rotations at specific viewing angles compared to theoretical predictions for low optical depths. This is due to the geometrical properties of the bow shock combined with multiple scattering effects. For dust scattering, the polarization signature is strongly affected by wavelength, dust grain properties, and viewing angle. The behavior of the polarization as a function of wavelength in these cases can distinguish among different dust models for the local ISM. In the case of SPH density structures, I investigate how the polarization changes as a function of the evolutionary phase of the SWBS. My dissertation compares these simulations with polarization data from Betelgeuse and other massive stars with bow shocks. I discuss the

Distribution of luminous bacteria and bacterial luminescence in the equatorial region of the Indian Ocean

Digital Repository Service at National Institute of Oceanography (India)

Ramaiah, N.; Chandramohan, D.

to that of seawater, was noticed from the zooplankton samples. This may be due to the autoinduction of luciferase synthesis or the accumulation of autoinducer in the luminous microflora living in close association with zooplankton...

A Massive Star Census of the Starburst Cluster R136

Science.gov (United States)

Crowther, Paul

2012-10-01

We propose to carry out a comprehensive census of the most massive stars in the central parsec {4"} of the starburst cluster, R136, which powers the Tarantula Nebula in the LMC. R136 is both sufficiently massive that the upper mass function is richly populated and young enough that its most massive stars have yet to explode as supernovae. The identification of very massive stars in R136, up to 300 solar masses, raises general questions of star formation, binarity and feedback in young massive clusters. The proposed STIS spectral survey of 36 stars more massive than 50 solar masses within R136 is ground-breaking, of legacy value, and is specifically tailored to a} yield physical properties; b} detect the majority of binaries by splitting observations between Cycles 19 and 20; c} measure rotational velocities, relevant for predictions of rotational mixing; d} quantify mass-loss properties for very massive stars; e} determine surface compositions; f} measure radial velocities, relevant for runaway stars and cluster dynamics; g} quantify radiative and mechanical feedback. This census will enable the mass function of very massive stars to be measured for the first time, as a result of incomplete and inadequate spectroscopy to date. It will also perfectly complement our Tarantula Survey, a ground-based VLT Large Programme, by including the most massive stars that are inaccessible to ground-based visual spectroscopy due to severe crowding. These surveys, together with existing integrated UV and optical studies will enable 30 Doradus to serve as a bona-fide template for unresolved extragalactic starburst regions.

Reappraising the concept of massive transfusion in trauma

DEFF Research Database (Denmark)

Stanworth, Simon J; Morris, Timothy P; Gaarder, Christine

2010-01-01

ABSTRACT : INTRODUCTION : The massive-transfusion concept was introduced to recognize the dilutional complications resulting from large volumes of packed red blood cells (PRBCs). Definitions of massive transfusion vary and lack supporting clinical evidence. Damage-control resuscitation regimens o...

Massive stars and X-ray pulsars

International Nuclear Information System (INIS)

Henrichs, H.

1982-01-01

This thesis is a collection of 7 separate articles entitled: long term changes in ultraviolet lines in γ CAS, UV observations of γ CAS: intermittent mass-loss enhancement, episodic mass loss in γ CAS and in other early-type stars, spin-up and spin-down of accreting neutron stars, an excentric close binary model for the X Persei system, has a 97 minute periodicity in 4U 1700-37/HD 153919 really been discovered, and, mass loss and stellar wind in massive X-ray binaries. (Articles 1, 2, 5, 6 and 7 have been previously published). The first three articles are concerned with the irregular mass loss in massive stars. The fourth critically reviews thoughts since 1972 on the origin of the changes in periodicity shown by X-ray pulsars. The last articles indicate the relation between massive stars and X-ray pulsars. (C.F.)

An effective theory of massive gauge bosons

International Nuclear Information System (INIS)

Doria, R.M.; Helayel Neto, J.A.

1986-01-01

The coupling of a group-valued massive scalar field to a gauge field through a symmetric rank-2 field strenght is studied. By considering energies very small compared with the mass of the scalar and invoking the decoupling theorem, one is left with a low-energy effective theory describing a dynamics of massive vector fields. (Author) [pt

Massive gravity with mass term in three dimensions

International Nuclear Information System (INIS)

Nakasone, Masashi; Oda, Ichiro

2009-01-01

We analyze the effect of the Pauli-Fierz mass term on a recently established, new massive gravity theory in three space-time dimensions. We show that the Pauli-Fierz mass term makes the new massive gravity theory nonunitary. Moreover, although we add the gravitational Chern-Simons term to this model, the situation remains unchanged and the theory stays nonunitary despite that the structure of the graviton propagator is greatly changed. Thus, the Pauli-Fierz mass term is not allowed to coexist with mass-generating higher-derivative terms in the new massive gravity.

Smart design to resolve spectral overlapping of phosphor-in-glass for high-powered remote-type white light-emitting devices.

Science.gov (United States)

Lee, Jin Seok; Arunkumar, P; Kim, Sunghoon; Lee, In Jae; Lee, Hyungeui; Im, Won Bin

2014-02-15

The white light-emitting diode (WLED) is a state-of-the-art solid state technology, which has replaced conventional lighting systems due to its reduced energy consumption, its reliability, and long life. However, the WLED presents acute challenges in device engineering, due to its lack of color purity, efficacy, and thermal stability of the lighting devices. The prime cause for inadequacies in color purity and luminous efficiency is the spectral overlapping of red components with yellow/green emissions when generating white light by pumping a blue InGaN chip with yellow YAG:Ce³⁺ phosphor, where red phosphor is included, to compensate for deficiencies in the red region. An innovative strategy was formulated to resolve this spectral overlapping by alternatively arranging phosphor-in-glass (PiG) through cutting and reassembling the commercial red CaAlSiN₃:Eu²⁺ and green Lu₃Al₅O₁₂:Ce³⁺ PiG. PiGs were fabricated using glass frits with a low softening temperature of 600°C, which exhibited excellent thermal stability and high transparency, improving life time even at an operating temperature of 200°C. This strategy overcomes the spectral overlapping issue more efficiently than the randomly mixed and patented stacking design of multiple phosphors for a remote-type WLED. The protocol for the current design of PiG possesses excellent thermal and chemical stability with high luminous efficiency and color purity is an attempt to make smarter solid state lighting for high-powered remote-type white light-emitting devices.

Live-cell Microscopy and Fluorescence-based Measurement of Luminal pH in Intracellular Organelles

Directory of Open Access Journals (Sweden)

Li Ma

2017-08-01

Full Text Available Luminal pH is an important functional feature of intracellular organelles. Acidification of the lumen of organelles such as endosomes, lysosomes, and the Golgi apparatus plays a critical role in fundamental cellular processes. As such, measurement of the luminal pH of these organelles has relevance to both basic research and translational research. At the same time, accurate measurement of intraorganellar pH in living cells can be challenging and may be a limiting hurdle for research in some areas. Here, we describe three powerful methods to measure rigorously the luminal pH of different intracellular organelles, focusing on endosomes, lysosomes, and the Golgi apparatus. The described methods are based on live imaging of pH-sensitive fluorescent probes and include: (1 A protocol based on quantitative, ratiometric measurement of endocytosis of pH-sensitive and pH-insensitive fluorescent conjugates of transferrin; (2 A protocol for the use of proteins tagged with a ratiometric variant of the pH-sensitive intrinsically fluorescent protein pHluorin; and (3 A protocol using the fluorescent dye LysoSensor™. We describe necessary reagents, key procedures, and methods and equipment for data acquisition and analysis. Examples of implementation of the protocols are provided for cultured cells derived from a cancer cell line and for primary cultures of mouse hippocampal neurons. In addition, we present strengths and weaknesses of the different described intraorganellar pH measurement methods. These protocols are likely to be of benefit to many researchers, from basic scientists to those conducting translational research with a focus on diseases in patient-derived cells.

Luminal epithelium in endometrial fragments affects their vascularization, growth and morphological development into endometriosis-like lesions in mice.

Science.gov (United States)

Feng, Dilu; Menger, Michael D; Wang, Hongbo; Laschke, Matthias W

2014-02-01

In endometriosis research, endometriosis-like lesions are usually induced in rodents by transplantation of isolated endometrial tissue fragments to ectopic sites. In the present study, we investigated whether this approach is affected by the cellular composition of the grafts. For this purpose, endometrial tissue fragments covered with luminal epithelium (LE(+)) and without luminal epithelium (LE(-)) were transplanted from transgenic green-fluorescent-protein-positive (GFP(+)) donor mice into the dorsal skinfold chamber of GFP(-) wild-type recipient animals to analyze their vascularization, growth and morphology by means of repetitive intravital fluorescence microscopy, histology and immunohistochemistry during a 14-day observation period. LE(-) fragments developed into typical endometriosis-like lesions with cyst-like dilated endometrial glands and a well-vascularized endometrial stroma. In contrast, LE(+) fragments exhibited a polypoid morphology and a significantly reduced blood perfusion after engraftment, because the luminal epithelium prevented the vascular interconnection with the microvasculature of the surrounding host tissue. This was associated with a markedly decreased growth rate of LE(+) lesions compared with LE(-) lesions. In addition, we found that many GFP(+) microvessels grew outside the LE(-) lesions and developed interconnections to the host microvasculature, indicating that inosculation is an important mechanism in the vascularization process of endometriosis-like lesions. Our findings demonstrate that the luminal epithelium crucially affects the vascularization, growth and morphology of endometriosis-like lesions. Therefore, it is of major importance to standardize the cellular composition of endometrial grafts in order to increase the validity and reliability of pre-clinical rodent studies in endometriosis research.

Luminal epithelium in endometrial fragments affects their vascularization, growth and morphological development into endometriosis-like lesions in mice

Directory of Open Access Journals (Sweden)

Dilu Feng

2014-02-01

Full Text Available In endometriosis research, endometriosis-like lesions are usually induced in rodents by transplantation of isolated endometrial tissue fragments to ectopic sites. In the present study, we investigated whether this approach is affected by the cellular composition of the grafts. For this purpose, endometrial tissue fragments covered with luminal epithelium (LE+ and without luminal epithelium (LE− were transplanted from transgenic green-fluorescent-protein-positive (GFP+ donor mice into the dorsal skinfold chamber of GFP− wild-type recipient animals to analyze their vascularization, growth and morphology by means of repetitive intravital fluorescence microscopy, histology and immunohistochemistry during a 14-day observation period. LE− fragments developed into typical endometriosis-like lesions with cyst-like dilated endometrial glands and a well-vascularized endometrial stroma. In contrast, LE+ fragments exhibited a polypoid morphology and a significantly reduced blood perfusion after engraftment, because the luminal epithelium prevented the vascular interconnection with the microvasculature of the surrounding host tissue. This was associated with a markedly decreased growth rate of LE+ lesions compared with LE− lesions. In addition, we found that many GFP+ microvessels grew outside the LE− lesions and developed interconnections to the host microvasculature, indicating that inosculation is an important mechanism in the vascularization process of endometriosis-like lesions. Our findings demonstrate that the luminal epithelium crucially affects the vascularization, growth and morphology of endometriosis-like lesions. Therefore, it is of major importance to standardize the cellular composition of endometrial grafts in order to increase the validity and reliability of pre-clinical rodent studies in endometriosis research.

Magnetic resonance evaluation of luminal patency after polylactide stent implantation: an experimental study in a rabbit aorta model

International Nuclear Information System (INIS)

Hietala, Eeva-Maija; Salminen, Ulla-Stina; Harjula, Ari L.J.; Maasilta, Paula; Staahls, Anders; Vaelimaa, Tero; Kivisaari, Leena

2003-01-01

Intravascular metallic stents cause magnetic field distortions, disturbing luminal detection. Our aim was to evaluate the effect of polylactic acid (PLA) stents on magnetic resonance angiography (MRA). Biodegradable double spiral helical PLA stents (n=12) or stainless steel (SS) (n=6) stents were implanted into the infrarenal aortas of New Zealand White rabbits. All SS- and 6 PLA-stented animals as well as 6 non-operated control rabbits were imaged with gadolinium-enhanced MRA (1.5 T), and infrarenal aortic diameters (proximal, distal, and narrowest), together with the stent artifact, were measured. Six of the PLA-stented rabbits were followed up, and MRA was assessed at 2, 6, 9, and 12 months after the stent implantation. Image artifacts caused by the SS stents were visualized in all cases. The PLA stents caused no magnetic field distortion, allowing imaging of the underlying vessel including the vessel lumen. In the follow-up group of 6 rabbits with a PLA stent, 5 of 6 were patent at the end of the follow-up of 12 months. These stents allowed luminal detection at all time points, with no significant differences in aortic measurements emerging during the whole follow-up period. When immediately postoperatively scanned SS and PLA rabbits were compared with controls, no differences were observable in proximal diameters. Instead, the percentage of distal luminal loss was greater in the PLA-stented rabbits, as compared with SS stents (p<0.01). The PLA stenting in small vessels allows evaluation of luminal patency with MRA both immediately after implantation and during follow-up. (orig.)

Reappraising the concept of massive transfusion in trauma

NARCIS (Netherlands)

Stanworth, Simon J.; Morris, Timothy P.; Gaarder, Christine; Goslings, J. Carel; Maegele, Marc; Cohen, Mitchell J.; König, Thomas C.; Davenport, Ross A.; Pittet, Jean-Francois; Johansson, Pär I.; Allard, Shubha; Johnson, Tony; Brohi, Karim

2010-01-01

The massive-transfusion concept was introduced to recognize the dilutional complications resulting from large volumes of packed red blood cells (PRBCs). Definitions of massive transfusion vary and lack supporting clinical evidence. Damage-control resuscitation regimens of modern trauma care are

Numerosity estimation in visual stimuli in the absence of luminance-based cues.

Directory of Open Access Journals (Sweden)

Peter Kramer

2011-02-01

Full Text Available Numerosity estimation is a basic preverbal ability that humans share with many animal species and that is believed to be foundational of numeracy skills. It is notoriously difficult, however, to establish whether numerosity estimation is based on numerosity itself, or on one or more non-numerical cues like-in visual stimuli-spatial extent and density. Frequently, different non-numerical cues are held constant on different trials. This strategy, however, still allows numerosity estimation to be based on a combination of non-numerical cues rather than on any particular one by itself.Here we introduce a novel method, based on second-order (contrast-based visual motion, to create stimuli that exclude all first-order (luminance-based cues to numerosity. We show that numerosities can be estimated almost as well in second-order motion as in first-order motion.The results show that numerosity estimation need not be based on first-order spatial filtering, first-order density perception, or any other processing of luminance-based cues to numerosity. Our method can be used as an effective tool to control non-numerical variables in studies of numerosity estimation.

Massive-Star Magnetospheres: Now in 3-D!

Science.gov (United States)

Townsend, Richard

Magnetic fields are unexpected in massive stars, due to the absence of a dynamo convection zone beneath their surface layers. Nevertheless, kilogauss-strength, ordered fields were detected in a small subset of these stars over three decades ago, and the intervening years have witnessed the steady expansion of this subset. A distinctive feature of magnetic massive stars is that they harbor magnetospheres --- circumstellar environments where the magnetic field interacts strongly with the star's radiation-driven wind, confining it and channelling it into energetic shocks. A wide range of observational signatures are associated with these magnetospheres, in diagnostics ranging from X-rays all the way through to radio emission. Moreover, these magnetospheres can play an important role in massive-star evolution, by amplifying angular momentum loss in the wind. Recent progress in understanding massive-star magnetospheres has largely been driven by magnetohydrodynamical (MHD) simulations. However, these have been restricted to two- dimensional axisymmetric configurations, with three-dimensional configurations possible only in certain special cases. These restrictions are limiting further progress; we therefore propose to develop completely general three-dimensional models for the magnetospheres of massive stars, on the one hand to understand their observational properties and exploit them as plasma-physics laboratories, and on the other to gain a comprehensive understanding of how they influence the evolution of their host star. For weak- and intermediate-field stars, the models will be based on 3-D MHD simulations using a modified version of the ZEUS-MP code. For strong-field stars, we will extend our existing Rigid Field Hydrodynamics (RFHD) code to handle completely arbitrary field topologies. To explore a putative 'photoionization-moderated mass loss' mechanism for massive-star magnetospheres, we will also further develop a photoionization code we have recently

Time-resolved methods in biophysics. 6. Time-resolved Laue crystallography as a tool to investigate photo-activated protein dynamics.

Science.gov (United States)

Bourgeois, Dominique; Schotte, Friedrich; Brunori, Maurizio; Vallone, Beatrice

2007-10-01

When polychromatic X-rays are shined onto crystalline material, they generate a Laue diffraction pattern. At third generation synchrotron radiation sources, a single X-ray pulse of approximately 100 ps duration is enough to produce interpretable Laue data from biomolecular crystals. Thus, by initiating biological turnover in a crystalline protein, structural changes along the reaction pathway may be filmed by ultra-fast Laue diffraction. Using laser-light as a trigger, transient species in photosensitive macromolecules can be captured at near atomic resolution with sub-nanosecond time-resolution. Such pump-probe Laue experiments have now reached an outstanding level of sophistication and have found a domain of excellence in the investigation of light-sensitive proteins undergoing cyclic photo-reactions and producing stiff crystals. The main theoretical concepts of Laue diffraction and the challenges associated with time-resolved experiments on biological crystals are recalled. The recent advances in the design of experiments are presented in terms of instrumental choices, data collection strategy and data processing, and some of the inherent difficulties of the method are highlighted. The discussion is based on the example of myoglobin, a protein that has traversed the whole history of pump-probe Laue diffraction, and for which a massive amount of data have provided considerable insight into the understanding of protein dynamics.

Key Technologies in Massive MIMO

Directory of Open Access Journals (Sweden)

Hu Qiang

2018-01-01

Full Text Available The explosive growth of wireless data traffic in the future fifth generation mobile communication system (5G has led researchers to develop new disruptive technologies. As an extension of traditional MIMO technology, massive MIMO can greatly improve the throughput rate and energy efficiency, and can effectively improve the link reliability and data transmission rate, which is an important research direction of 5G wireless communication. Massive MIMO technology is nearly three years to get a new technology of rapid development and it through a lot of increasing the number of antenna communication, using very duplex communication mode, make the system spectrum efficiency to an unprecedented height.

Three-dimensional shape perception from chromatic orientation flows

Science.gov (United States)

Zaidi, Qasim; Li, Andrea

2010-01-01

The role of chromatic information in 3-D shape perception is controversial. We resolve this controversy by showing that chromatic orientation flows are sufficient for accurate perception of 3-D shape. Chromatic flows required less cone contrast to convey shape than did achromatic flows, thus ruling out luminance artifacts as a problem. Luminance artifacts were also ruled out by a protanope’s inability to see 3-D shape from chromatic flows. Since chromatic orientation flows can only be extracted from retinal images by neurons that are responsive to color modulations and selective for orientation, the psychophysical results also resolve the controversy over the existence of such neurons. In addition, we show that identification of 3-D shapes from chromatic flows can be masked by luminance modulations, indicating that it is subserved by orientation-tuned neurons sensitive to both chromatic and luminance modulations. PMID:16961963

Complicated Massive Choledochal Cyst: A Case Report | Okoromah ...

African Journals Online (AJOL)

Choledochal cysts are rare congenital anomalies resulting from congenital dilatations of the common bile duct (CBD) and usually they present during infancy with cholestatic jaundice. This report is on a massive-sized choledochal cyst associated with massive abdominal distention, respiratory embarrassment, postprandial ...

THE AVERAGE PHYSICAL PROPERTIES AND STAR FORMATION HISTORIES OF THE UV-BRIGHTEST STAR-FORMING GALAXIES AT z ∼ 3.7

International Nuclear Information System (INIS)

Lee, Kyoung-Soo; Glikman, Eilat; Dey, Arjun; Reddy, Naveen; Jannuzi, Buell T.; Brown, Michael J. I.; Gonzalez, Anthony H.; Cooper, Michael C.; Fan Xiaohui; Bian Fuyan; Stern, Daniel; Brodwin, Mark; Cooray, Asantha

2011-01-01

We investigate the average physical properties and star formation histories (SFHs) of the most UV-luminous star-forming galaxies at z ∼ 3.7. Our results are based on the average spectral energy distributions (SEDs), constructed from stacked optical-to-infrared photometry, of a sample of the 1913 most UV-luminous star-forming galaxies found in 5.3 deg 2 of the NOAO Deep Wide-Field Survey. We find that the shape of the average SED in the rest optical and infrared is fairly constant with UV luminosity, i.e., more UV-luminous galaxies are, on average, also more luminous at longer wavelengths. In the rest UV, however, the spectral slope β (≡ dlogF λ /dlogλ; measured at 0.13 μm rest UV and thus star formation rates (SFRs) scale closely with stellar mass such that more UV-luminous galaxies are also more massive, (2) the median ages indicate that the stellar populations are relatively young (200-400 Myr) and show little correlation with UV luminosity, and (3) more UV-luminous galaxies are dustier than their less-luminous counterparts, such that L ∼ 4-5L* galaxies are extincted up to A(1600) = 2 mag while L ∼ L* galaxies have A(1600) = 0.7-1.5 mag. We argue that the average SFHs of UV-luminous galaxies are better described by models in which SFR increases with time in order to simultaneously reproduce the tight correlation between the UV-derived SFR and stellar mass and their universally young ages. We demonstrate the potential of measurements of the SFR-M * relation at multiple redshifts to discriminate between simple models of SFHs. Finally, we discuss the fate of these UV-brightest galaxies in the next 1-2 Gyr and their possible connection to the most massive galaxies at z ∼ 2.

Observations of Bright Massive Stars Using Small Size Telescopes

Science.gov (United States)

Beradze, Sopia; Kochiashvili, Nino

2017-11-01

The size of a telescope determines goals and objects of observations. During the latest decades it becomes more and more difficult to get photometric data of bright stars because most of telescopes of small sizes do not operate already. But there are rather interesting questions connected to the properties and evolution ties between different types of massive stars. Multi-wavelength photometric data are needed for solution of some of them. We are presenting our observational plans of bright Massive X-ray binaries, WR and LBV stars using a small size telescope. All these stars, which are presented in the poster are observational targets of Sopia Beradze's future PhD thesis. We already have got very interesting results on the reddening and possible future eruption of the massive hypergiant star P Cygni. Therefore, we decided to choose some additional interesting massive stars of different type for future observations. All Massive stars play an important role in the chemical evolution of galaxies because of they have very high mass loss - up to 10-4M⊙/a year. Our targets are on different evolutionary stages and three of them are the members of massive binaries. We plan to do UBVRI photometric observations of these stars using the 48 cm Cassegrain telescope of the Abastumani Astrophisical Observatory.

Massive Star Clusters in Ongoing Galaxy Interactions: Clues to Cluster Formation

Science.gov (United States)

Keel, William C.; Borne, Kirk D.

2003-09-01

We present HST WFPC2 observations, supplemented by ground-based Hα data, of the star-cluster populations in two pairs of interacting galaxies selected for being in very different kinds of encounters seen at different stages. Dynamical information and n-body simulations provide the details of encounter geometry, mass ratio, and timing. In NGC 5752/4 we are seeing a weak encounter, well past closest approach, after about 2.5×108 yr. The large spiral NGC 5754 has a normal population of disk clusters, while the fainter companion NGC 5752 exhibits a rich population of luminous clusters with a flatter luminosity function. The strong, ongoing encounter in NGC 6621/2, seen about 1.0×108 yr past closest approach between roughly equal-mass galaxies, has produced an extensive population of luminous clusters, particularly young and luminous in a small region between the two nuclei. This region is dynamically interesting, with such a strong perturbation in the velocity field that the rotation curve reverses sign. From these results, in comparison with other strongly interacting systems discussed in the literature, cluster formation requires a threshold level of perturbation, with stage of the interaction a less important factor. The location of the most active star formation in NGC 6621/2 draws attention to a possible role for the Toomre stability threshold in shaping star formation in interacting galaxies. The rich cluster populations in NGC 5752 and NGC 6621 show that direct contact between gas-rich galaxy disks is not a requirement to form luminous clusters and that they can be triggered by processes happening within a single galaxy disk (albeit triggered by external perturbations). Based on observations with the NASA/ESA Hubble Space Telescope, obtained at the Space Telescope Science Institute, which is operated by the Association of Universities for Research in Astronomy, Inc., under NASA contract NAS 5-26555.

Extensive tumor reconstruction with massive allograft

International Nuclear Information System (INIS)

Zulmi Wan

1999-01-01

Massive deep-frozen bone allografts were implanted in four patients after wide tumor resection. Two cases were solitary proximal femur metastases, secondary to Thyroid cancer and breast cancer respectively; while the other two cases were primary in nature i.e. Chondrosarcoma proximal humerus and Osteosarcoma proximal femur. All were treated with a cemented alloprosthesis except in the upper limb where shoulder fusion was performed. Augmentation of these techniques were done with a segment 1 free vascularised fibular composite graft to the proximal femur of breast secondaries and proximal humerus Chondrosarcoma. Coverage of the wound of the latter was also contributed by lattisimus dorsi flap. The present investigations demonstrated the massive bone allografts were intimately anchored by host bone and there had been no evidence of aseptic loosening at the graft-cement interface. This study showed that with good effective tumor control, reconstructive surgery with massive allografts represented a good alternative to prosthetic implants in tumors of the limbs. No infection was seen in all four cases

Luminance and chromatic signals interact differently with melanopsin activation to control the pupil light response.

Science.gov (United States)

Barrionuevo, Pablo A; Cao, Dingcai

2016-09-01

Intrinsically photosensitive retinal ganglion cells (ipRGCs) express the photopigment melanopsin. These cells receive afferent inputs from rods and cones, which provide inputs to the postreceptoral visual pathways. It is unknown, however, how melanopsin activation is integrated with postreceptoral signals to control the pupillary light reflex. This study reports human flicker pupillary responses measured using stimuli generated with a five-primary photostimulator that selectively modulated melanopsin, rod, S-, M-, and L-cone excitations in isolation, or in combination to produce postreceptoral signals. We first analyzed the light adaptation behavior of melanopsin activation and rod and cones signals. Second, we determined how melanopsin is integrated with postreceptoral signals by testing with cone luminance, chromatic blue-yellow, and chromatic red-green stimuli that were processed by magnocellular (MC), koniocellular (KC), and parvocellular (PC) pathways, respectively. A combined rod and melanopsin response was also measured. The relative phase of the postreceptoral signals was varied with respect to the melanopsin phase. The results showed that light adaptation behavior for all conditions was weaker than typical Weber adaptation. Melanopsin activation combined linearly with luminance, S-cone, and rod inputs, suggesting the locus of integration with MC and KC signals was retinal. The melanopsin contribution to phasic pupil responses was lower than luminance contributions, but much higher than S-cone contributions. Chromatic red-green modulation interacted with melanopsin activation nonlinearly as described by a "winner-takes-all" process, suggesting the integration with PC signals might be mediated by a postretinal site.