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Sample records for ludwig tauscher 1939-2008

  1. Ludwig Tauscher (1939-2008)

    CERN Multimedia

    2008-01-01

    Dear Colleagues, It is with deep sorrow and regret that we inform you that our colleague and friend Ludwig Tauscher passed away on Sunday 23 November after a heart attack. Ludwig studied physics at the University of Heidelberg, where he obtained his PhD in 1966. After several postdoctoral appointments at the MPI Heidelberg, and the Universities of Konstanz and Karlsruhe, he joined the University of Basel, where he became Professor of Physics in 1985. Ludwig devoted his entire professional life to teaching and experimental physics. He arrived at CERN in the early seventies, where he performed several experiments at the SC and at the PS, studying exotic atoms with various probes such as μ-, π-, K-, and Σ-. In the early eighties he searched for the production of nucleon-antinucleon bound states at the PS, a subject that was the main motivation for the construction of the LEAR storage ring. At LEAR he studied neutral meson productio...

  2. Wittgenstein, Ludwig

    DEFF Research Database (Denmark)

    Presskorn-Thygesen, Thomas; Basbøll, Thomas

    2017-01-01

    Ludwig Josef Johann Wittgenstein was a British-Austrian philosopher, widely considered one of most influential philosophers of the twentieth century. His early work played a significant role in twentieth-century logical positivism while his later work has been a main methodological influence...... in the works of key social theorists such as Pierre Bourdieu, Jürgen Habermas, and Anthony Giddens. The entry briefly describes Wittgenstein's philosophy and summarizes his overall influence within social theory....

  3. Ludwig: My Pedagogical Part

    Science.gov (United States)

    Beckett, David

    2009-01-01

    Ludwig Wittgenstein taught only a couple of Australian philosophers, at Cambridge in the late 1940s, and one of them, Frank "Camo" Jackson (Chair, Philosophy, Monash University) taught the author epistemology and philosophical psychology in the 1970s. In this article, the author describes how this teaching was central to his subsequent…

  4. Ludwig Boltzmann: Atomic genius

    Energy Technology Data Exchange (ETDEWEB)

    Cercignani, C. [Department of Mathematics, Politecnico di Milano (Italy)]. E-mail: carcer@mate.polimi.it

    2006-09-15

    On the centenary of the death of Ludwig Boltzmann, Carlo Cercignani examines the immense contributions of the man who pioneered our understanding of the atomic nature of matter. The man who first gave a convincing explanation of the irreversibility of the macroscopic world and the symmetry of the laws of physics was the Austrian physicist Ludwig Boltzmann, who tragically committed suicide 100 years ago this month. One of the key figures in the development of the atomic theory of matter, Boltzmann's fame will be forever linked to two fundamental contributions to science. The first was his interpretation of 'entropy' as a mathematically well-defined measure of the disorder of atoms. The second was his derivation of what is now known as the Boltzmann equation, which describes the statistical properties of a gas as made up of molecules. The equation, which described for the first time how a probability can evolve with time, allowed Boltzmann to explain why macroscopic phenomena are irreversible. The key point is that while microscopic objects like atoms can behave reversibly, we never see broken coffee cups reforming because it would involve a long series of highly improbable interactions - and not because it is forbidden by the laws of physics. (U.K.)

  5. [Friedrich Ludwig von Maydelli pildid Baltimaade ajaloost = Friedrich Ludwig von Maydells Baltische Geschichte in Bildern = Friedrich Ludwig von Maydell ́s Baltic history in images] / Ulrike Plath

    Index Scriptorium Estoniae

    Plath, Ulrike, 1972-

    2014-01-01

    Arvustus: Friedrich Ludwig von Maydelli pildid Baltimaade ajaloost = Friedrich Ludwig von Maydells Baltische Geschichte in Bildern = Friedrich Ludwig von Maydell ́s Baltic history in images. Eesti kunstimuuseum, Kadrioru kunstimuuseum. Tallinn 2013

  6. Ludwig Boltzmann - pioneer of atomistics and evolution

    International Nuclear Information System (INIS)

    Stiller, W.

    1986-01-01

    At first a short introduction to Ludwig Boltzmann's life (1844 - 1906) and work is given. Some theoretical results of his work (H-theorem, classical Boltzmann statistics, Boltzmann's kinetic equation) are treated in detail. His experimental work is briefly discussed. In addition Boltzmann's philosophical work is characterized. Finally, the influence of Boltzmann's ideas on our time is investigated. (author)

  7. Ludwig Leichhardt und Alexander von Humboldt

    Directory of Open Access Journals (Sweden)

    Aliya-Katarina Südfels

    2012-10-01

    Full Text Available Zusammenfassung Im Juli des Jahres 1841 kommt es zu einem Treffen zwischen zwei Männern, das zunächst belanglos erscheint, sich aber Jahre später als wichtige historische Begebenheit herausstellen wird. In seinem Pariser Büro empfängt der 71jährige Naturforscher Alexander von Humboldt den jungen Preußen Ludwig Leichhardt. Der angehende Naturwissenschaftler erhofft sich Zuspruch und Empfehlung des berühmten Alexander von Humboldts. Die Unterredung ist kurz und verläuft für Leichhardt ergebnislos. Es wird das einzige Treffen der beiden Naturwissenschaftler bleiben. Aus heutiger Sicht unverständlich, da Ludwig Leichhardt und Alexander von Humboldt mehr verband, als ihre Leidenschaft für die Naturwissenschaften. Viel zu wenig ist sich bis jetzt den biographischen Analogien und den vergleichbaren geographischen Leistungen der beiden Preußen gewidmet worden. Abstract During July 1841 a meeting between two men takes place, which seems to have been extraneous, but turns out to be a significant historical incident. 71 year old natural scientist Alexander von Humboldt welcomes young Ludwig Leichhardt from Prussia in his office in Paris. The prospective young scientist expects help and references from famous Alexander von Humboldt. The conversation is short and ends from Leichhardt’s point of view without results. Unfortunately this is going to be the only meeting between the two scientists even though the two Prussians have more in common than their passion for the natural sciences. Way too seldomly have biographical analogy and geographical productivity of the two men been compared. Résumé En juillet 1841 une rencontre entre deux hommes a lieu, qui au premier abord semble sans importance, mais qui des années plus tard est considéré comme un événement historique majeur. Dans son bureau parisien, le naturaliste Alexandre de Humboldt, alors âgé de 71 ans, reçoit le jeune Prussien Ludwig Leichhardt. Le jeune scientifique en devenir

  8. Ludwig Boltzmann - The Man and His Work

    International Nuclear Information System (INIS)

    Broda, E.

    1982-01-01

    It is argued that Ludwig Boltzmann was, along with Newton and Maxwell, one of the three greatest theoretical physicists of classical times. It is less generally known that he was also a powerful realist-materialist philosopher and a keen opponent of Ernst Mach's positivism and of the philosophical idealism of Berkeley, Hegel and Schopenhauer. Boltzmann was also opposed to Kant. Moreover, he had a lively interest in biology and especially in Darwinian evolution, and he should be taken as one of the founders of biophysics. Boltzmann discussed the origin of life and of the mind. Finally, he also was a most vigorous, colourful and attractive person. (author)

  9. Ludwig's angina after severe thrombocytopenic purpura associated with dengue fever

    Directory of Open Access Journals (Sweden)

    Maria Antonia Campos

    2014-01-01

    Full Text Available Here, we report a case of Ludwig's angina, which required surgery because of toothache. The patient had dengue and severe thrombocytopenia as confirmed by clinical and laboratory diagnoses. However, dengue is not included among the predisposing factors for Ludwig's angina.

  10. Obituary: Philip M. Solomon, 1939-2008

    Science.gov (United States)

    Scoville, Nick

    2009-01-01

    Philip Solomon, one of the pioneers and leading researchers in molecular astrophysics, died on 30 April 2008 at his apartment on the upper west side of Manhattan after a battle with cancer. His pioneering research included both theoretical and very extensive observational studies of stellar atmospheres, interstellar molecules, high redshift galaxies, and the Earth's stratosphere. Phil was Distinguished Professor at The State University of New York [SUNY], Stony Brook, where he had been since 1974. Phil was born on 29 March 1939 in Manhattan, New York City, to Nat and Betty Solomon. Nat Solomon was a labor organizer and a printer. Phil attended the University of Wisconsin, where he received his BS in 1959 and where he met his future wife Sheila who was studying art. His Ph.D., "On the Role of Light Molecules in Astrophysics," was also from the University of Wisconsin under the guidance of Art Code and Bob Bless. After postdoctoral positions at Princeton and lectureships at Columbia and the University of California, San Diego, Phil spent two years as a Professor at the University of Minnesota. After two years at the Institute for Advanced Study in Princeton, he came to SUNY, Stony Brook, as Professor of Astronomy in the Department of Earth and Space Sciences. In 1988 Phil was selected as a Humboldt Senior Distinguished Scientist, and, in 1999, he was honored with the rank of Distinguished Professor at SUNY. Phil took sabbatical and other leaves at Churchill College and the Institute of Astronomy, Cambridge; the Institute for Advanced Study; l'Ecole Normale Superieure, Paris; Institut d'Astrophysique, Paris; and the Institut de Radioastronomie Millimetrique [IRAM], France. Phil published more than 160 papers and supervised seven Ph.D. students. He served on numerous review, visiting, and advisory panels. Phil's first theoretical research focused on opacity and abundance of light molecules such as H2, CO, and CN in stellar atmospheres, but then shifted quickly to the formation, excitation, and astrophysics of interstellar molecules, which had just been discovered in the late 1960s. In 1969, Phil and Chandra Wickramasinghe were among the first to suggest that the denser interstellar clouds, which were deficient in atomic hydrogen, were principally molecular hydrogen with the H2 formed on the surface of cold dust grains and protected from dissociating UV by a self-shielding H2 layer at the cloud surface. With L. Lucy, Phil then developed the radiative transfer and mass-loss mechanism operative in hot OB star winds and QSOs--where the radiative momentum is absorbed in resonance lines of ions. In the late 1960s and early 1970s, the detection and mapping of interstellar molecules moved rapidly from the early discoveries of maser emission in H2O and OH to the thermal emission lines of simple molecules like CO, CN, CS, and HCN, to more complex species containing up to thirteen atoms. Phil was a major force in pushing these new detections and in using the thermal emission as astrophysical probes. This explosive growth of spectroscopic detections occurred primarily as a result of Phil's collaborations with A. Penzias, K. Jefferts, R. Wilson, and P. Thaddeus, along with other competing groups using the NRAO 36-foot telescope at Kitt Peak. This was a most exciting period with the mm-wave window finally accessible to spectroscopy and each observing run on the telescope typically yielded one or two new detections. Phil was probably the one most responsible for providing the astrophysical motivation to push the technology towards mm-wavelengths. He clearly elucidated the fact that high densities were required for the thermal excitation of the higher dipole moment molecules such CS and HCN--at the same time pointing out, for the first time, the critical role of line photon trapping in the optically thick lines. In collaboration with N. Scoville and D. Sanders, Phil initiated the early surveys of CO emission from the Milky Way molecular gas. They first pointed out that the molecular gas resides largely in self-gravitating clouds (not in pressure equilibrium with the diffuse atomic and ionized gas) and coined the term Giant Molecular Clouds. They also discovered that the molecular gas had a Galactic distribution very different from the atomic gas--a massive central concentration within 300 pc of the Galactic center and the molecular cloud "ring" at 4 to 8 kpc radius. Throughout this work, he clearly elucidated the astrophysical importance of the dense molecular clouds as the sites of virtually all star formation. During this period, Phil, in collaboration with W. Klemperer, provided important theoretical insight into the formation of simple diatomic molecules via gas-phase charge exchange reactions. As the sensitivity of mm-wave receivers improved, Phil extended the observations of CO and HCN emission first to nearby galaxies in collaboration with J. Barrett and L. Sage and then to higher luminosity, more-distant objects with Y. Gao, D. Downes, and P. Vanden Bout. Solomon and Gao very significantly showed that for the most luminous infrared galaxies, the infrared luminosities were linearly proportional to the amount of dense, star-forming gas (as traced by HCN) and hence, they argued, that the source of luminosity could be entirely star formation rather than quasar activity. With Downes, Phil was introduced to mm-wave interferometry (at last, I should say, since he was basically a single-dish astronomer at heart), and they were among the first to produce high-resolution images of the most luminous infrared galaxies. Phil's most recent work, in collaboration with Vanden Bout, Carilli, and Maddalena to detect CO and HCN from the highest redshift galaxies was on-going, but resulted in a recent Annual Reviews paper that provides a forward look to the future of this field. Phil also realized that mm-wave spectroscopy could be used for remote sensing of the terrestrial stratosphere to trace the abundance of ClO and hence monitor the ozone layer depletion. This work, in collaboration with R. deZafra, J. Barrett, and A. Parrish, led to their setting up remote, automated observing systems in Antarctica and in Hawaii; these efforts continued over twenty years up to the present. For those of us who collaborated with Phil, he will be greatly missed. Phil had a keen sense for interesting and significant science; he had a real enthusiasm for discovery; and he enjoyed the competition of forefront scientific research where recognition of significance was vital but where discussion of interpretation was rational, albeit with strong argument. The pleasure of an observing run with Phil was supreme due to his enthusiasm and focus on the astrophysics; these runs also were creative since if the original plans did not quite pan out, he was always ready to modify the observations to take advantage of what one learned from the data coming into the telescope. Often this resulted in much better science--in contrast to the current paradigm with fixed observing programs and queue observing. Phil was also a major presence at scientific meetings giving stimulating talks and provoking challenging discussions. Phil is survived by his wife Sheila, daughter Nina, son-in-law John, granddaughter Sarah, and brother Mark.

  11. Obituary: Ludwig Friedrich Oster, 1931-2003

    Science.gov (United States)

    Sofia, Sabatino; Altschuler, Martin D.

    2003-12-01

    Ludwig Friedrich Oster died at the Anchorage Nursing and Rehabilitation Center in Salisbury, MD on 28 February 2003, of complications from advanced Alzheimer's disease. He is survived by his wife Cheryl M. (Oroian) and his two children by a previous marriage, Ulrika and Mattias Oster. He had a distinguished career both as a researcher in solar physics and as a science administrator in the National Science Foundation. Ludwig was born on 8 March 1931 in Konstanz, Germany and emigrated to the U.S. in 1958, acquiring American citizenship in 1963. His mother and father were Emma Josefine (Schwarz) and Ludwig Friedrich Oster. He got a BS degree in physics at the University of Freiburg under the guidance of Prof. K. O. Kiepenheuer in 1951, and a MS (1954) and PhD from the University of Kiel in 1956 under the guidance of Prof. A. Unsold. From 1956 to 1958 he was a Fellow of the German Science Council at Kiel and, upon his arrival to the US in 1958, he became a Postdoctoral Research Associate in the Physics Department of Yale University. He became an Assistant Professor of Physics and Astrophysics at Yale in 1960 and five years later he was promoted to Associate Professor. In 1967 he became an Associate Professor of Physics and Astrophysics at the University of Colorado and a Fellow of the Joint Institute for Laboratory Astrophysics; he was promoted to Full Professor in 1970. In 1981 he was a Visiting Professor at Johns Hopkins University, and shortly thereafter became a National Research Council Senior Associate at NASA/Goddard Space Flight Center in Greenbelt, MD, where he worked on solar variability. He joined the National Science Foundation in 1983, where he became the Program Manager for the National Radio Astronomy Observatory in the Division of Astronomical Sciences of the Foundation; he remained there until his retirement in 1996. His early work, started in Germany and continued at Yale, concerned radiation mechanisms related to solar phenomena. His works on

  12. Ludwig Tieck: meandros góticos

    Directory of Open Access Journals (Sweden)

    Karin Volobuef

    2012-11-01

    Full Text Available http://dx.doi.org/10.5007/2175-8026.2012n62p153   Ludwig Tieck (1773-1853 foi um dos pioneiros do Romantismo alemão ao lado de figuras como Novalis, Wackenroder, os irmãos August e Friedrich Schlegel, Schleiermacher, Schelling. Grande admirador de Shakespeare e Calderón de la Barca, Tieck concebia a literatura como terreno supranacional e como área de convergência de diferentes tradições e perspectivas. Com isso, absorveu inúmeros elementos da cultura popular (contos de fadas, lendas, superstições e os fundiu a vertentes de sua época, entre as quais a da narrativa gótica e de horror, em voga desde a segunda metade do século XVIII. Em Tieck, o macabro tornase expressão de questionamentos sobre a relação entre sujeito e mundo e sobre a própria noção (inspirada no senso comum de que existiria uma realidade única e independente do ponto de vista daquele que a observa ou descreve. Tieck formulou esteticamente indagações que ecoaram pelo Romantismo alemão, expressando anseios e inquietações indissociáveis de sua produção poético-literária.   Ludwig Tieck (1773-1853 was a pioneer of German Romanticism alongside figures such as Novalis, Wackenroder, brothers August and Friedrich Schlegel, Schleiermacher, Schelling. A great admirer of Shakespeare and Calderón de la Barca, Tieck envisioned literature as a supranational terrain and an area of convergence of different traditions and perspectives. Thus he absorbed numerous elements from popular culture (fairy tales, legends, superstitions and merged with the trends of his time, among which the mid eighteenth-century gothic and horror narrative. In Tieck the macabre becomes an expression of questions about the relationship between the subject and on the very notion (based on common sense that there would be a single reality and independent from the point of view of who observes or describes. Tieck aesthetically formulated questions that echoed throughout German romanticism

  13. Fragile peace: Northern balance outlasts the celebrated Ludwig case

    International Nuclear Information System (INIS)

    Jaremko, G.

    2000-01-01

    Conflicts between communities and the environment on the one hand, and industry on the other are discussed against the background of the charges against Wiebo Ludwig, chief of a religious commune at Hythe, Alberta, who stands accused of terrorist attacks against oil and gas installations. The community is divided in its opinion about Mr. Ludwig; some line up on his side saying that by doing what he did, he focused attention on flaring, and although the government will never admit it, Ludwig's actions may have been the most important factor in the government's decision to place restrictions on the practice. Others, many among them critics of the industry, bristle at the mention of Ludwig, pointing to the many benefits that the industry brought to Alberta and accusing Ludwig of upsetting a delicate balance between the farmers and the industry, which existed in a symbiotic relationship ever since oil was first discovered in the province. The fact remains that the oil industry made many farmers wealthy, and by providing employment, it saved many of the smaller and marginal farms from going under. Despite the Ludwig affair, the pace of industrial expansion has not changed in Peace country. Some 1,300 new wells, double the 1999 total, are being forecast for the area in 2000, and steady employment by oilfield service companies is being reported throughout the region

  14. University Observatory, Ludwig-Maximilians-Universität

    Science.gov (United States)

    Murdin, P.

    2000-11-01

    The University Observatory of Ludwig-Maximilians-Universität was founded in 1816. Astronomers who worked or graduated at the Munich Observatory include: Fraunhofer, Soldner, Lamont, Seeliger and Karl Schwarzschild. At present four professors and ten staff astronomers work here. Funding comes from the Bavarian Government, the German Science Foundation, and other German and European research progra...

  15. Teaching with Purpose: An Interview with Thomas E. Ludwig

    Science.gov (United States)

    Ludwig, Timothy D.; Ludwig, David J.

    2010-01-01

    Thomas E. Ludwig is the John Dirk Werkman Professor of Psychology at Hope College, where he joined the faculty in 1977 after receiving his PhD in development and aging from Washington University in St. Louis. His research focuses on developmental issues in cognitive neuropsychology. He is also the author or coauthor of more than a dozen sets of…

  16. Beethoven, Ludwig van: Violinkonzert D-Dur op. 61

    Index Scriptorium Estoniae

    1997-01-01

    Uuest heliplaadist "Beethoven, Ludwig van: Violinkonzert D-Dur op. 61 (Kadenz: Alfred Schnittke). Romanzen für Violine und Orchester op. 40 und 50. Estonian National Symphony Orchestra, Arvo Volmer". Globe GLO 5155, distribution Talis (CD:153F). 1996. TT:1h 01'56"

  17. PIV Analysis of Ludwig Prandtl's Historic Flow Visualization Films

    OpenAIRE

    Willert, Christian; Kompenhans, Jürgen

    2010-01-01

    Around 1930 Ludwig Prandtl and his colleagues O. Tietjens and W. M\\"uller published two films with visualizations of flows around surface piercing obstacles to illustrate the unsteady process of flow separation. These visualizations were achieved by recording the motion of fine particles sprinkled onto the water surface in water channels. The resulting images meet the relevant criteria of properly seeded recordings for particle image velocimetry (PIV). Processing these image sequences with mo...

  18. Methodological solipsism and kaleidoscopic worlds of Ludwig Mauritz Lachmann

    Directory of Open Access Journals (Sweden)

    Bazhenov Grigory, A.

    2015-03-01

    Full Text Available Among the Austrians fifth generation occupies a special place disciple of Friedrich A. von Hayek, economist, distracting from the overall flow of the Austrians, Ludwig M. Lachmann. Using the framework of his theory of the fundamental assumptions of the Austrian School (individualism, subjectivism, Lachmann did not try to pull them under the base of normative conclusions about the structure of the economic system of society, but rather, an attempt to build a more rigorous theory of the social world order. German economist, recognizing the importance of the concept of subjective value, pay attention to its insufficiency and stressed the need to incorporate to construct a theory of subjectivity expectations that brings his views with the views of John Maynard Keynes. Following George Shackle Ludwig Lachmann believes that the economy is similar to a kaleidoscope: the elements of economic reality are in constant rearrangement, creating continuously changing each other short-lived and unstable patterns. The author of the paper analyzes the concepts and ideas of Ludwig M. Lachmann, noting both the strengths and weaknesses of his theory. The author shows the importance of the theoretical development of the German economist for modern economics.

  19. Sordera, tragedia y muerte de Ludwig van Beethoven

    Directory of Open Access Journals (Sweden)

    Darío Morón Díaz

    2008-07-01

    Full Text Available

    La sordera de Ludwig van Beethoven fue atribuida a distintas enfermedades: a una neuritis
    acústica debido a la fiebre tifoidea, a la sífilis, a la hepatitis, a una colitis, al reumatismo, a abscesos,
    a una criopatia debida al frío y a la osificación del tejido cartilaginoso que conduce al oído ínterno,
    también mencionaron la sarcoidosis.
    Dos hechos fueron fundamentales para desechar tales especulaciones: el primero, la decisión del
    joven Ferdinand Hiller, que el 27 de marzo de 1827 cortó un mechón de cabello del cadáver de Ludwig
    van Beethoven. El segundo, el avance científico de la medicina moderna. Ambos acontecimientos han
    permitido profundizar con certeza en la etiología u origen de la sordera de Beethoven y la variada síntomatología que sufrió el genio musical.

    Esbozo biográfico
    EL 16 de diciembre de 1770, en Bonn, nació Ludwig van Beethoven, hijo de Johann Beethoven y
    Maria Magdalena Keverich; el matrimonio tuvo siete hijos, cuatro fallecieron siendo niños y tres sobrevivieron: Ludwig, Kaspar Antón Karl y Nicolás Johann.
    El padre de Beethoven fue dipsómano, debido a los excesos alcohólicos y en medio de los escándalos el
    padre agredía al niño. Deambulaba entre la Iglesia y la taberna. María Magdalena por el contrario era tierna y afectuosa con su hijo, situación que por contraste servía de refugio a Ludwig.

  20. Management of Ludwig's angina in pregnancy: a review of 10 cases ...

    African Journals Online (AJOL)

    Background: Ludwig's angina is a rapidly spreading cellulitis that may produce upper airway obstruction often leading to death. Aim: The present paper reviews the management of Ludwig's angina in the third trimester of pregnancy. The inherent dangers to the mother and her unborn child are highlighted. Materials and ...

  1. Fifty years of mathematical physics selected works of Ludwig Faddeev

    CERN Document Server

    Faddeev, Ludwig; Niemi, Antti J

    2016-01-01

    This unique volume summarizes with a historical perspective several of the major scientific achievements of Ludwig Faddeev, with a foreword by Nobel Laureate C N Yang. The volume that spans over fifty years of Faddeev's career begins where he started his own scientific research, in the subject of scattering theory and the three-body problem. It then continues to describe Faddeev's contributions to automorphic functions, followed by an extensive account of his many fundamental contributions to quantum field theory including his original article on ghosts with Popov. Faddeev's contributions to soliton theory and integrable models are then described, followed by a survey of his work on quantum groups. The final scientific section is devoted to Faddeev's contemporary research including articles on his long-term interest in constructing knotted solitons and understanding confinement. The volume concludes with his personal view on science and mathematical physics in particular.

  2. [Ludwig Wittgenstein (1889-1951) and the "wound shock"].

    Science.gov (United States)

    Gentili, Marc E

    2015-01-01

    Ludwig Wittgenstein was born in 1889 in Vienna. As a scholar in Cambdrige University, his philosophical achievements are still major regarding the foundations of mathematics and language. In 1939, he took a job as a porter at London Guys' Hospital then under the Blitz. Wittgenstein met Drs. Grant and Reeve who worked in a dedicated "traumatic shock" under the auspices of the Medical Research Council unit, a unit which then moved to the Royal Victoria Infirmary in Newcastle; Wittgenstein followed them as a technician and improved the preparation of fine pieces of histology fixed by paraffin. He also invented a new device to record pulse pressure and paradoxical pulse search in laboratory rats. At the end of the war, he returned to Cambridge until 1949 and died in 1951.

  3. Ludwig von Bertalanffy's organismic view on the theory of evolution.

    Science.gov (United States)

    Drack, Manfred

    2015-03-01

    Ludwig von Bertalanffy was a key figure in the advancement of theoretical biology. His early considerations already led him to recognize the necessity of considering the organism as a system, as an organization of parts and processes. He termed the resulting research program organismic biology, which he extended to all basic questions of biology and almost all areas of biology, hence also to the theory of evolution. This article begins by outlining the rather unknown (because often written in German) research of Bertalanffy in the field of theoretical biology. The basics of the organismic approach are then described. This is followed by Bertalanffy's considerations on the theory of evolution, in which he used methods from theoretical biology and then introduced his own, organismic, view on evolution, leading to the demand for finding laws of evolution. Finally, his view on the concept of homology is presented. © 2015 Wiley Periodicals, Inc.

  4. Ludwig Edinger: the vertebrate series and comparative neuroanatomy.

    Science.gov (United States)

    Patton, Paul

    2015-01-01

    At the end of the nineteenth century, Ludwig Edinger completed the first comparative survey of the microscopic anatomy of vertebrate brains. He is regarded as the founder of the field of comparative neuroanatomy. Modern commentators have misunderstood him to have espoused an anti-Darwinian linear view of brain evolution, harkening to the metaphysics of the scala naturae. This understanding arises, in part, from an increasingly contested view of nineteenth-century morphology in Germany. Edinger did espouse a progressionist, though not strictly linear, view of forebrain evolution, but his work also provided carefully documented evidence that brain stem structures vary in complexity independently from one another and across species in a manner that is not compatible with linear progress. This led Edinger to reject progressionism for all brain structures other than the forebrain roof, based on reasoning not too dissimilar from those his successors used to dismiss it for the forebrain roof.

  5. Ludwig Wittgenstein and Language Games (A Literary Application

    Directory of Open Access Journals (Sweden)

    Mirela Arsith

    2011-12-01

    Full Text Available The hypothesis which we assume is that a language cannot transform only one way, but more ways of seeing the world. Therefore, the speakers will not be stuck in a rigid framework of a single belief system. As the modes of discourse are changed, the speakers accomplish, constantly, ideological changes. As Ludwig Wittgenstein sustained, the “key” of our language is not in the mind but a way of life that pushes us towards certain ways of using signs, which are the language games. The approach that we started, namely to investigate various language games in the John Fowles’ novel The Magician, we have identified not only various types of language games, but, in the spirit of Austrian origin philosopher, we searched to make our expressions more accurate. We believe that according to the applications on the text The Magician, we were able to illustrate how Wittgenstein theme of “language games” can be exploited explicitly in the literature. What we showed is that between the activities called language games there are more relations of functional analogies or conceptual functionality.

  6. Axiomatic unsharp quantum theory (From Mackey to Ludwig and Piron)

    Science.gov (United States)

    Cattaneo, Gianpiero; Laudisa, Federico

    1994-05-01

    On the basis of Mackey's axiomatic approach to quantum physics or, equivalently, of a “state-event-probability” (SEVP) structure, using a quite standard “fuzzification” procedure, a set of unsharp events (or “effects”) is constructed and the corresponding “state-effect-probability” (SEFP) structure is introduced. The introduction of some suitable axioms gives rise to a partially ordered structure of quantum Brouwer-Zadeh (BZ) poset; i.e., a poset endowed with two nonusual orthocomplementation mappings, a fuzzy-like orthocomplementation, and an intuitionistic-like orthocomplementation, whose set of sharp elements is an orthomodular complete lattice. As customary, by these orthocomplementations the two modal-like necessity and possibility operators are introduced, and it is shown that Ludwig's and Jauch-Piron's approaches to quantum physics are “interpreted” in complete SEFP. As a marginal result, a standard procedure to construct a lot of unsharp realizations starting from any sharp realization of a fixed observable is given, and the relationship among sharp and corresponding unsharp realizations is studied.

  7. Tracing Spasmodic Dysphonia: The Source of Ludwig Traube's Priority.

    Science.gov (United States)

    Lorch, Marjorie Perlman; Whurr, Renata

    2016-08-01

    Since the mid-20th century, one citation is given historical priority as the first description of spasmodic dysphonia (SD): Ludwig Traube's 1871 case of the "spastic form of nervous hoarseness." Our objective is to understand how this case serves as the foundation of understanding laryngeal movement disorders. The original German paper was located and translated. Bibliographical and bibliometric methods are used to determine the citation history of this original source over the past 140 years. Although secondary citations in contemporary publications typically credit Traube for establishing the clinical entity SD, his case does not conform to currently accepted diagnostic features. Citation patterns indicate the source of Traube's priority is publications by Arnold and Luchsinger, mid-20th-century ENT clinicians, particularly their influential 1965 textbook used to train US and UK clinicians on voice disorders for several generations. Sometimes secondary citations in medical literature lead to the inadvertent perpetuation of factual misrepresentation. The clinical picture of Traube's original case does not represent what clinicians would recognize as SD today. The rich 19th-century literature on voice disorders is a valuable resource for present day clinicians. © The Author(s) 2016.

  8. Ludwig Edinger (1855-1918): founder of modern neuroanatomy.

    Science.gov (United States)

    Prithishkumar, Ivan James

    2012-03-01

    Ludwig Edinger, a German neurologist is considered as one of the founders of modern neuroanatomy. He was conferred the degree of Doctor of Medicine at the University of Strassburg. His observation of small living organisms under a microscope at an early age led him to study medicine. Edinger had many discoveries to his credit. He was the first to describe the ventral and dorsal spinocerebellar tracts, to distinguish between paleo-encephalon and neo-encephalon, and between paleo-cerebellum and neo-cerebellum. He coined the terms "gnosis" and "praxis," which were later adopted in psychological descriptions of agnosia and apraxia. He identified the Edinger-Westphal nucleus in 1885 and was the first to describe the syndrome of thalamic pain. Edinger worked with renowned clinicians and published a large number of papers. He founded the Neurological Institute at the Goethe University in Frankfurt, which is the oldest neurological Institute in Germany. Edinger was a rare combination of a profound scientist, a brilliant teacher, a fine artist, and a noted hypnotist. While at the height of his career, he underwent a surgery and died a few hours later. It was his last will that his brain should be dissected in his own institute. It showed extraordinarily well-developed occipital lobes as well as other unusual features. Copyright © 2011 Wiley-Liss, Inc.

  9. A CASE OF LUDWiG ANGiNA ENDING WITH MORTALITY

    Directory of Open Access Journals (Sweden)

    Abdullah Onur Goksel

    2013-06-01

    Full Text Available Ludwig angina is a serious infection which is defines as edema, quickly progressing gangrenous sellulitis of soft tissues in neck and flor of the mouth. Airway obstruction is the most common cause of death. We present a case who applied to our outpatient clinic with a swelling under jaw and neck and was dignosed a a Ludwig Anjina. Broad spectrum antibiotherapy was given and followed without tracheotomy. He died because of cardiac arrest. [J Contemp Med 2013; 3(2.000: 112-115

  10. The Influence of Ernst Mach and Ludwig Boltzmann on Albert Einstein

    International Nuclear Information System (INIS)

    Broda, E.

    1979-01-01

    This document, written by Engelbert Broda in 1979, analyses the influence of Ernst Mach and Ludwig Boltzmann on Albert Einstein. Broda describes how Einstein and his scientific thinking benefited from Mach’s criticism on classical mechanics and its basic concepts like absolute time and absolute space. This criticism encouraged Einstein in the time he worked on his special relativity. On the other side Broda writes about the influence of Ludwig Boltzman, an atomist, whose scientific work and research prepared the ground for Einsteins work on the quantum-structure of electromagnetic radiation or the discovery of the photoelectric effect. (nowak)

  11. Beethoven, Ludwig van: Concerto pour violon op. 61 / Jean-Michel Molkhou

    Index Scriptorium Estoniae

    Molkhou, Jean-Michel

    1997-01-01

    Uuest heliplaadist "Beethoven, Ludwig van: Concerto pour violon op. 61 (cadence Schnittke). Les 2 Romances op. 40 et 50. Orchestre Symphonique National d'Estonie, Arvo Volmer" Globe GLO 5155, distribution Talis (CD:153F). 1996. TT:1h 01'56"

  12. [Carl Ludwig and his place in the history of kidney physiology].

    Science.gov (United States)

    From, Jesper

    2015-01-01

    Only very little was known about the physiology of the kidneys until the middle of the 19th century. The turning point came in 1842 when the famous German physiologist and physician Carl Ludwig (1816-1895) presented a theory about a two-step process (filtration and reabsorption) leading to the excretion of urine. This paper turns the highlights on Ludwig and the period in which he lived. It also tells the story about the anatomical studies in the 17th century and the chemical approaches to urine and kidney physiology in the 18th century preceding the research of Carl Ludwig. The theory of filtration and reabsorption was opposed by another theory (the secretion theory) regarding the kidney as a gland, like for instance the salivary glands. The origin of this theory can be dated back to Marcello Malpighi (1628-1694) in the Renaissance, but it was carried further on by William Bowman (1816-1892) and especially Rudolph Heidenhain (1834-1897) in the 19th century. The research in the 1920's and 1930's marked the end of the fight between the two theories. It proofed that Ludwig was right and it gave him posthumously the recognition that he all the time had deserved.

  13. Von den Liven von Oesel / August Ludwig Schlözer

    Index Scriptorium Estoniae

    Schlözer, August Ludwig

    2008-01-01

    Avaldatud Eberhard Winkleri initsiatiivil A. L. Schlözeri teose põhjal: Gesammelte Nachrichten von den Ueberresten der Liven, in Livland und Kurland. (1770), mis moodustab osa teosest: Schlözer, August Ludwig. M. Johann Joseph Haigold's Beylagen zum Neuveränderten Russland. Zweiter Theil. Riga und Leipzig, 1770

  14. Rudolf Ludwig Mössbauer - jeho život, efekt a spektroskopie

    Czech Academy of Sciences Publication Activity Database

    Závěta, Karel; Kohout, J.; Lančok, Adriana

    2012-01-01

    Roč. 62, č. 1 (2012), s. 51-61 ISSN 0009-0700 Institutional research plan: CEZ:AV0Z10100520; CEZ:AV0Z40320502 Keywords : Rudolf Ludwig Mössbauer * resonance absorption * Mössbauer spectroscopy * Mars mission Subject RIV: BM - Solid Matter Physics ; Magnetism

  15. Models, Their Application, and Scientific Anticipation: Ludwig Boltzmann's Work as Tacit Knowing

    Science.gov (United States)

    Schmitt, Richard Henry

    2011-01-01

    Ludwig Boltzmann's work in theoretical physics exhibits an approach to the construction of theory that he transmitted to the succeeding generation by example. It involved the construction of clear models, allowed more than one, and was not based solely on the existing facts, with the intent of examining and criticizing the assumptions that made…

  16. A Challenge to Ludwig von Mises’s Theory of Probability

    Directory of Open Access Journals (Sweden)

    Mark R. Crovelli

    2010-10-01

    Full Text Available The most interesting and completely overlooked aspect of Ludwig von Mises’s theory of probability is the total absence of any explicit definition for probability in his theory. This paper examines Mises’s theory of probability in light of the fact that his theory possesses no definition for probability. It is argued, first, that Mises’s theory differs in important respects from his brother’s famous theory of probability. A defense of the subjective definition for probability is then provided, which is subsequently used to critique Ludwig von Mises’s theory. It is argued that only the subjective definition for probability comports with Mises’s other philosophical positions. Since Mises did not provide an explicit definition for probability, it is suggested that he ought to have adopted a subjective definition.

  17. Os fundamentos transcendentais da daseinsanalyse psiquiátrica de Ludwig Binswanger

    Directory of Open Access Journals (Sweden)

    Rodrigo Alvarenga

    Full Text Available Ludwig Binswanger compreendeu que era necessário reestruturar o método de investigação e abordagem dos fenômenos psicóticos, pelo afastamento da ontologia cartesiana do sujeito e do objeto, o qual pressupunha o dualismo e o solipsismo da consciência, para fundar uma abordagem intersubjetiva da psiquiatria. O objetivo desta pesquisa é justamente examinar esse percurso fenomenológico da Daseinsanalyse psiquiátrica de Ludwig Binswanger, no que se refere ao cumprimento daquilo para o qual ela própria se propôs, por meio da assimilação da investigação transcendental no campo das psicoses.

  18. Ludwig August krahv Mellin kui talurahva sõber ja estofiil / Indrek Jürjo

    Index Scriptorium Estoniae

    Jürjo, Indrek, 1956-2009

    2003-01-01

    Ludwig August Mellini (1754-1835) suhtumisest eesti ja läti talurahvasse, pärisorjusesse ja tema huvist eestlaste rahvuskarakteri ning rahvuskultuuri vastu. Krahv Mellin oli aastatel 1783-1786 Riia kreisi kreisipeamees ja -kohtunik, 1797-1818 osales aktiivselt 19. sajandi esimeste kümnendite agraarreformides, tema isa Carl Johann von Mellin oli esimene mõisnik Läänemere provintsides, kes umbes 18. sajandi keskpaiku andis oma Tuhala mõisa talupoegadele välja eraõiguse. Lisad: Ludwig August v. Mellini kiri Kuramaa Kirjanduse ja Kunsti Seltsile. BÎriņi, 25. juuni 1822 ; Mellini "Rigaische Stadtblätter'is" avaldamata jäänud artikkel

  19. A model of Piron's preparation-question structures in Ludwig's selection structures

    Science.gov (United States)

    Cattaneo, Gianpiero; Nisticò, Giuseppe

    1993-03-01

    We give a model of the basic Jauch-Piron (JP) approach to quantum physics, i.e., of “preparation-question structure” (with four basic axioms and without axioms C, P, A), in terms of Ludwig's “selection structure”; in the latter structure the primitive notion of “individual sample” of a physical entity is formally described (without making reference to any probability concept). Once we interpret Piron's concept of “question” in Ludwig's context of a selection structure, we find that there is no difficulty in formalizing notions such as “performable together questions”; moreover, results such as “ α ˜˜= α” or “( αδ Β)˜= α ˜▽ Β˜” can be formally proved. We develop the theory along the lines of the JP approach; the set of JP propositions is derived and it turns out to be a complete lattice, as happens in Piron's theory, but with a different physical interpretation of the lattice operations. Finally, we study some connections between the standard Ludwig foundation and our approach.

  20. DESEJO DE LUZ: O CRISTIANISMO E O SURGIMENTO DA FILOSOFIA MODERNA EM LUDWIG FEUERBACH / A DESIRE FOR LIGHT: CHRISTIANITY AND THE EMERGENCE OF MODERN PHILOSOPHY IN LUDWIG FEUERBACH

    Directory of Open Access Journals (Sweden)

    Chrysantho Figueiredo

    2015-04-01

    Full Text Available This is a review of Ludwig Feuerbach’s book introduction Geshichte der Neuern Philosophie von Bacon bis Spinoza. The original text is in German, the review is in Portuguese. However, we present here, attached, the translated text, also unpublished and original. In 1841's The Essence of Christianity, Feuerbach presents in a most complete way his own version of the radical humanism which excited the young hegelians of his generation. However, it is between 1833 and 1838 that Feuerbach formulates his own philosophical point of view from the critique of the major philosophical systems of modernity. The History of Philosophy from Bacon to Spinoza, published in 1833, is the first of his historicalphilosophical works which, apart from the critique of the philosophers indicated by the title, presents also a singular feuerbachian vision of history as a whole, showing how modern philosophy emerges from the inherent contradictions of the Christian religious spirit.

  1. Estetyka a granice języka. Ludwig Wittgenstein i Arthur C. Danto

    Directory of Open Access Journals (Sweden)

    Karolina GLAZOR-POMYKAŁA

    2016-12-01

    Full Text Available The article is an attempt to pinpoint the areas of Ludwig Wittgenstein aesthetic thought, in which he is crossing the borders principally imposed upon the method and the language of his philosophy. I am directing my attention to metaphysical and mystical motifs of his reflection devoted to aesthetics, the essence of art and the essence of reality. I wish to discuss this issue based on the texts of Arthur C. Danto containing analysis of chosen notions of Wittgenstein’s aesthetic investigations. Additionally in this matter I am appealing to appropriate theses of Leszek Sosnowski and Wojciech Sady, concerning above issues.

  2. Ludwig's angina in children anesthesiologist's nightmare: Case series and review of literature

    Directory of Open Access Journals (Sweden)

    Maitree Pandey

    2017-01-01

    Full Text Available Ludwig's angina is potentially lethal, rapidly spreading cellulitis of the floor of mouth and neck. The anticipated difficult airway becomes even more challenging when it occurs in children. In children, the larynx is positioned relatively higher in the neck, and one does not have the option for blind nasal intubation or awake fiberoptic, which otherwise is the technique of choice in adult patients. We present the clinical course of 16 children and highlight various problems encountered during the anesthetic management of six children who required emergency surgical drainage under general anesthesia.

  3. Dreams, hallucinations, moving statues, and Ekphrasis in Ludwig Tieck's visual writings

    OpenAIRE

    Rockelmann, Joseph D

    2014-01-01

    When reading Ludwig Tieck's texts the reader becomes aware that dreams, the unconscious, and art play a key role. This study seeks to posit that Ekphrasis and dream interpretation are similar due to both analyzing a visual image and attempting to translate the visual into the verbal in order to gain a better and more complete understanding of it. G.E. Lessing believed that poetry and the visual arts were equal since each art form has its own strengths and when combined they create a complete ...

  4. Hertzian Dynamic Models In Ludwig Wittgenstein’s Theory Of Logic

    Directory of Open Access Journals (Sweden)

    Andreea Eșanu

    2013-05-01

    Full Text Available During the last century the social sciences grew from the stage of speculative system building to a more mature development in which empirical data are sought for the significance they can have for systematic theories. A lot of work in this field concerns itself with determining the methodological and conceptual prerequisites for a mature science of human reasoning and behavior. Modeling human reasoning and human behavior, although currently focused on social and economic phenomena like organizations, organizational knowledge, leadership, cooperation etc., are historically dependent upon modeling natural phenomena in physical science, precisely because physical science tackles successfully the issue of building upon empirical data. This paper pursues an apparently small, but nonetheless significant, historical claim concerning the “relative position of human reasoning and mechanics” a claim made possible by the development of late 19th century’s epistemology of science (mainly Heinrich Hertz’s and theoretical philosophy (Ludwig Wittgenstein. The main idea of the paper is that Ludwig Wittgenstein’s concept of “logical representation”, seen as a landmark for what human reasoning is about, is an intricate analogue to the Hertzian “dynamic models” from the Principles of Mechanics. This analogy is analyzed and explained with regard to the problem of the “logic of color”.

  5. Ludwig Wittgenstein

    DEFF Research Database (Denmark)

    Munch, Anders V.

    2006-01-01

    Filosoffen Wittgenstein var involveret i et byggeri sammen med arkitekten Paul Engelmann, elev af Adolf Loos. De filosofiske overvejelser om begrebet livsform kan belyse ideerne om den moderne arkitektur hos Loos, mens Loos' stilbegreb omvendt kan belyse sprogfilosofien hos Wittgenstein....

  6. Studies on the genus Eupenicillium Ludwig I. Taxonomy and nomenclature of Penicillia in relation to their sclerotioid ascocarpic states

    NARCIS (Netherlands)

    Stolk, Amelia C.; Scott, De B.

    1967-01-01

    The ascocarpic genus Eupenicillium Ludwig has been re-instated and reviewed taxonomically. It accommodates the perfect states of species characterized by pseudoparenchymatic or sclerotioid cleistothecia. The imperfect states belong to Penicillium Link ex Fries. Descriptions and synonomy of the genus

  7. [Ludwig II of Bavaria - the "fairy tale king": his last years from a psychiatric point of view].

    Science.gov (United States)

    V Zerssen, D

    2010-11-01

    Ludwig II of Bavaria (Germany) entered the political stage at the age of 18, following the premature death of his father Maximilian II in 1864. At that time, Ludwig was a very handsome, slender young man; he was enthusiastic and had a pronounced taste for fine arts and music, and was admired by the people as a "fairy tale king". However, already during the first years of his reign, he displayed traits that fulfilled the ICD-10 criteria for schizotypal disorder together with a combined cluster B personality disorder. They became even more pronounced over time. Towards the end of his life, Ludwig developed "imperial madness", a typical pattern of behavioural excesses including craving for power, splendour, construction, unrestrained spending, excessive eating and sexual exploitation, revenge with a tendency for cruelty, and an inclination for theatrical and sometimes irrational acts. This complex syndrome is usually manifested in excessively egocentric rulers who have almost unlimited power or, in the case of Ludwig II, an overwhelming desire to possess it. His imperial madness was possibly contributed to by an orbitofrontal brain syndrome. One conjecture is that this condition reflected a neurodegenerative process; another is that a primary deficit, initiated by brain damage following a severe bout of meningitis during Ludwig's babyhood, played a role. In this case, functional compensation by other brain areas may have eventually been counteracted by chronic substance abuse in his thirties. The monarch's life ended tragically when he was 40 by which time he had become adipose and had lost most of his teeth; meanwhile, he was placed under tutelage, dismissed and detained. Before his death by drowning in Lake Starnberg (suicide? attempted escape??), Ludwig apparently killed his psychiatrist, Bernhard von Gudden, who carelessly served as his sole attendant. Yet Ludwig's image as the beautiful fairy tale king is still alive in the hearts of successive generations of

  8. [Ludwig Rehn (1849-1930) and his importance in the development of modern surgery].

    Science.gov (United States)

    Sachs, M; Encke, A

    1996-01-01

    The unusual course of Ludwig Rehn's professional development directed him from a general practitioner close to Frankfurt am Main to his convocation as first Professor in ordinary for surgery to the Frankfurt University, which was newly established in 1914. Among his numerous publications, especially the following contributed immensely to the development of modern surgery: in 1884, he already described the healing of patients with Graves' disease by subtotal resection of the goiter; in 1885 he first described the high prevalence of bladder tumors in workers of an aniline factory; in 1886, he managed the first successful heart-suture after a stab-incision of the right ventricle; in 1897, he already performed an operation at the thoracal oesophagus, with an access via the posterior mediastinum; in 1920, he established the operative treatment (pericardectomy) of patients with a calcified pericarditis (armour heart).

  9. Atoms, mechanics, and probability Ludwig Boltzmann's statistico-mechanical writings : an exegesis

    CERN Document Server

    Darrigol, Olivier

    2018-01-01

    One of the pillars of modern science, statistical mechanics, owes much to one man, the Austrian physicist Ludwig Boltzmann (1844-1906). As a result of his unusual working and writing styles, his enormous contribution remains little read and poorly understood. The purpose of this book is to make the Boltzmann corpus more accessible to physicists, philosophers, and historians, and so give it new life. The means are introductory biographical and historical materials, detailed and lucid summaries of every relevant publication, and a final chapter of critical synthesis. Special attention is given to Boltzmann's theoretical tool-box and to his patient construction of lofty formal systems even before their full conceptual import could be known. This constructive tendency largely accounts for his lengthy style, for the abundance of new constructions, for the relative vagueness of their object--and for the puzzlement of commentators. This book will help the reader cross the stylistic barrier and see how ingeniously B...

  10. Ludwig Guttmann (1899-1980), Stoke Mandeville Hospital and the Paralympic Games.

    Science.gov (United States)

    Silver, John R

    2012-08-01

    On 27 July 2012 London is hosting the Olympic and the Paralympic Games. The Olympic Games will be attended by 17,000 athletes to be followed by the Paralympic Games with 4200 athletes from 150 countries, participating in 20 different sports. This multicultural event has grown in the last 60 years from a small competition between British and Dutch athletes on the lawns of Stoke Mandeville Hospital in Buckinghamshire. The Paralympic Movement was born out of the vision of Sir Ludwig Guttmann. Before World War II, most paraplegic patients died. Guttmann came to Stoke Mandeville Hospital in 1944 and instituted the modern treatment of spinal injuries which kept paraplegic patients alive. While exercise is an essential part of rehabilitation, developing strength and agility, and a paraplegic patient can only participate in competitive sport when he or she is fully rehabilitated so the sports movement grew out of the successful treatment of paraplegic patients.

  11. "On cyclic insanity" by Karl Ludwig Kahlbaum, MD: a translation and commentary.

    Science.gov (United States)

    Baethge, Christopher; Salvatore, Paola; Baldessarini, Ross J

    2003-01-01

    Karl Ludwig Kahlbaum (1828-1899) spent most of his professional career as director of a private psychiatric sanatorium in Germany. He remains influential for introducing his "clinical method" (based on considering the course of an illness as well as the signs and symptoms) of differential diagnosis of specific psychiatric syndromes and urging abandonment of the more unitary views of psychotic disorders favored by the leading German academic theorists of his time. Kahlbaum's approach to nosology, detailed in an 1863 monograph and other works, strongly influenced Kraepelin's views. However, remarkably few of the important writings of this keen clinical observer are available in English translation. His seminal lecture-essay "On Cyclic Insanity" [Uber cyklisches Irresein] of 1882 is translated into English here for the first time, with comments about its place in the history of the evolution of the concept of bipolar disorder, including its position as a link between Falret's folie circulaire and Kraepelin's manic-depressive insanity.

  12. Bayerische Staatsbibliothek Ludwig-Maximilian Universität München Historisches Seminar /Abteilung geschichtliche Wissenschaften, Projektbereich 'Digitale Tafelwerke Pilotprojekt Digitalisierung Sybel/Sickel: "Kaiserurkunden in Abbildungen"

    Directory of Open Access Journals (Sweden)

    Antonella Ghignoli

    2006-12-01

    Full Text Available Review of Bayerische Staatsbibliothek Ludwig-Maximilian Universität München Historisches Seminar /Abteilung geschichtliche Wissenschaften, Projektbereich 'Digitale Tafelwerke Pilotprojekt Digitalisierung Sybel/Sickel: "Kaiserurkunden in Abbildungen"

  13. A short biography of Hubert Ludwig and a note on the publication dates of his monograph Die Seewalzen (1889-1892).

    Science.gov (United States)

    Reich, Mike

    2015-12-03

    The dates of publication of Hubert Ludwig's (1852-1913) comprehensive monograph Die Seewalzen [= Sea cucumbers] are reviewed. The precise publication dates of his volume, originally published in 16 fascicles and 8 parts/issues, delivered between 1889 and 1892, has been re-examined. Additionally, a short biographical note on Hubert Ludwig's life and a discussion of all new taxa introduced by him in his monograph is given.

  14. Bomb-spike dating of a mummified baboon in Ludwig Cave, Namibia

    Directory of Open Access Journals (Sweden)

    Hodgins Greg

    2007-01-01

    Full Text Available In 1982 a mummified adult female baboon was discovered on a ledge in Ludwig Cave in Namibia. A toe bone was removed for dating in July 1995. AMS radiocarbon dating of bone collagen, tendon, and skin indicates a post-modern age. Application of the atomic bomb-spike calibration curve suggests death in late 1977 and an age at death of around 19 years. Baboons roost in the cave and the mummified female, along with a mummified juvenile male discovered in 2002 and three rotting corpses discovered in 1995, were probably chased by other baboons or by leopards down a ca. 6 m drop during the rainy season, and were unable to climb the steep and very slippery slope to escape. The large number of baboons trapped in the cave in less than 20 years, and mummification of two individuals on dry, dusty ledges in the cave, may explain why large numbers of baboon skeletons have been discovered in ancient bone breccias (up to 4 Ma old in a number of caves throughout Southern Africa.

  15. Mortimer Frank, Johann Ludwig Choulant, and the history of anatomical illustration.

    Science.gov (United States)

    Feibel, Robert M

    2018-01-01

    Mortimer Frank (1874-1919) was an ophthalmologist in Chicago, Illinois. He published a number of papers on the history of medicine, and was secretary of the Chicago Society of the History of Medicine and editor of their Bulletin. His major contribution to the history of medicine relates to the history of anatomical illustration. The classic book on that subject had been published in 1852 in German by the physician and historian, Johann Ludwig Choulant (1791-1861). However, by Frank's time this text was both out dated and out of print. Frank took on the tremendous project of translating Choulant's German text into English as History and Bibliography of Anatomic Illustration in Its Relation to Anatomic Science and The Graphic Arts. He improved Choulant's text with the results of his and other scholars' research, greatly enlarging the text. Frank supplemented the original book with a biography of Choulant, essays on anatomists not considered in the original text, and an essay on the history of anatomical illustration prior to those authors discussed by Choulant. This book, now referred to as Choulant/Frank, has been reprinted several times, and is still useful as a reference in this field, though some of its research is now dated.

  16. Implant dentistry curriculum in undergraduate education: part 2-program at the Albert-Ludwigs University, Freiburg, Germany.

    Science.gov (United States)

    Kroeplin, Birgit S; Strub, Joerg R

    2011-01-01

    The aim of this study was to describe the didactic and clinical undergraduate implant dentistry program of the Albert-Ludwigs University, Freiburg, Germany, with emphasis on the clinical implant experience. A detailed description of the implant curriculum at Albert-Ludwigs University is given with documented exemplary cases and additional flow charts. All students participate in 28 hours of lectures and approximately 64 hours of seminars with hands-on courses and gain clinical experience. All undergraduate students are eligible to place and restore oral implants. Emphasis is placed on prosthetic-driven planning of implant positions, three-dimensional imaging, and computer-guided implant placement. Implant restorations performed by undergraduate students comprise single crowns and small multiunit fixed dental prostheses in partially edentulous posterior maxillae and anterior or posterior mandibles, implant-retained overdentures (snap attachment) in edentulous patients, and telescopic fixed-removable dental prostheses on remaining teeth and strategically placed additional implants. Over the past 2.5 years, 51 patients were treated with 97 dental implants placed by students in the undergraduate program. Seventy-one restorations were inserted: 60.6% single crowns, 7% fixed dental protheses, 21.1% overdentures, and 11.3% telescopic fixed-removable dental prostheses. The implant survival rate was 98.9%. Because survival rates for dental implants placed and restored by students are comparable to those of experienced dentists, oral implant dentistry should be implemented as part of the undergraduate dental curriculum.

  17. Response to inquiry request from the Ludwig, Schilthuis, Boonstra, Wright, Bryzgorni and Johnstone families and Dr. W. O. Scott

    International Nuclear Information System (INIS)

    2000-01-01

    An EUB inquiry into oil and gas activities in the Hythe and Beaverlodge area in Alberta was requested by a number of families and individuals, living near the area, complaining of emissions from petroleum operations, as well as expressing concerns about increasing community frustration and intentional damage to petroleum facilities. During the Board's consideration of the request two members of the group, Wiebo Ludwig and Richard Boonstra, were charged with criminal offences related to damage to oil and gas facilities in northwestern Alberta. They were tried and convicted for these offences in April 2000. Subsequently, the Board denied the request for an inquiry on the grounds that the oil and gas operations identified by the families have been conducted in compliance with the terms of the respective companies' approvals, licences and permits, and the operations conformed to provincial standards. Furthermore, the families, especially the Ludwig, Boonstra and Schilthuis families, have consistently demonstrated a lack of cooperation over the years in participating in efforts initiated by the Board, industry and government, to find solutions to their concerns. Also, the Board found no objective evidence that the harmful effects identified by the families resulted from the lawful activities of the energy companies operating in the Hythe area. This Memorandum of Decision contains the detailed reasoning of the Board for denying the request for an inquiry, and to provide context, including facts about the extent, scope and performance of oil and gas operations in the area. 2 figs

  18. The International (Ludwig) Breast Cancer Study Group Trials I-IV: 15 years follow-up.

    Science.gov (United States)

    Castiglione-Gertsch, M; Johnsen, C; Goldhirsch, A; Gelber, R D; Rudenstam, C M; Collins, J; Lindtner, J; Hacking, A; Cortes-Funes, H; Forbes, J

    1994-10-01

    Adjuvant systemic therapy prolongs disease-free and overall survival in both pre- and postmenopausal patients. Available data shown benefit from multi-agent chemotherapy, prolonged tamoxifen treatment, and ovarian ablation, and that the combination of chemo- and endocrine therapy might be advantageous. In 1978 the International (Ludwig) Breast Cancer Study Group (IBCSG) initiated four complementary randomized controlled clinical trials to evaluate the roles of chemo-endocrine combinations or endocrine therapy alone in specific populations defined by risk (for pre- and perimenopausal patients) or by age (for postmenopausal patients). The results at 10 and 13 years' median follow-up for these trials are summarized in this report and are compared to those of the Overview meta-analysis with regard to chemo-endocrine or endocrine therapy combinations. Furthermore, types of first relapses by sites and second malignant diseases are reported. 1601 evaluable patients with node positive disease were included into the studies I-IV. In Trial I (491 premenopausal patients with 1-3 positive axillary nodes) we studied the addition of low-dose continuous prednisone (p) to a cyclophosphamide-methotrexate-fluorouracil (CMF) combination. In Trial II 327 premenopausal patients with four or more positive axillary nodes were randomized to one year CMFp or to a surgical oophorectomy followed by CMFp. In Trial III (463 postmenopausal patients 65 years old or younger), combined chemoendocrine therapy (one year of CMFp plus tamoxifen (T)) was compared to endocrine therapy (1 year of p + T) or to surgery alone. In Trial IV 320 postmenopausal patients 66 to 80 years old were treated either by surgery alone or by surgery followed by 1 year prednisone and tamoxifen. In Trial I the addition of prednisone allowed a higher dose of cytotoxics to be administered compared with CMF alone. Despite this increased dose intensity, 13-year disease-free survival (DFS) and overall survival (OS) were similar

  19. ON THE MAKING OF A SYSTEM THEORY OF LIFE: PAUL A WEISS AND LUDWIG VON BERTALANFFY’S CONCEPTUAL CONNECTION

    Science.gov (United States)

    Drack, Manfred; Apfalter, Wilfried; Pouvreau, David

    2010-01-01

    In this article, we review how two eminent Viennese system thinkers, Paul A Weiss and Ludwig von Bertalanffy, began to develop their own perspectives toward a system theory of life in the 1920s. Their work is especially rooted in experimental biology as performed at the Biologische Versuchsanstalt, as well as in philosophy, and they converge in basic concepts. We underline the conceptual connections of their thinking, among them the organism as an organized system, hierarchical organization, and primary activity. With their system thinking, both biologists shared a strong desire to overcome what they viewed as a “mechanistic” approach in biology. Their interpretations are relevant to the renaissance of system thinking in biology—“systems biology.” Unless otherwise noted, all translations are our own. PMID:18217527

  20. On the making of a system theory of life: Paul A Weiss and Ludwig von Bertalanffy's conceptual connection.

    Science.gov (United States)

    Drack, Manfred; Apfalter, Wilfried; Pouvreau, David

    2007-12-01

    In this article, we review how two eminent Viennese system thinkers, Paul A Weiss and Ludwig von Bertalanffy, began to develop their own perspectives toward a system theory of life in the 1920s. Their work is especially rooted in experimental biology as performed at the Biologische Versuchsanstalt, as well as in philosophy, and they converge in basic concepts. We underline the conceptual connections of their thinking, among them the organism as an organized system, hierarchical organization, and primary activity. With their system thinking, both biologists shared a strong desire to overcome what they viewed as a "mechanistic" approach in biology. Their interpretations are relevant to the renaissance of system thinking in biology--"systems biology." Unless otherwise noted, all translations are our own.

  1. ‘Wo soll ich hinfliehen vor diesem Mensch?’: Een luisteroefening in Ludwig Hofacker (1797−1828

    Directory of Open Access Journals (Sweden)

    Johan Kommers

    2013-09-01

    Full Text Available De aanwezigheid van de levende God in preken kunnen wij niet terzijde stellen of verontachtzamen. Waar dit wel gebeurt, daar wordt verkondiging een voordracht, zonder de volmacht. Orthodoxie komt in ademnood wanneer exegese en dogmatiek opgaan in een aantal meningen en waarbij het getuigenis van de Bijbel op de achtergrond komt. Ludwig Hofacker (1798–18281 was een prediker die in bijbelonderzoek en prediking zijn oor te luisteren legde aan de Bron. Het Woord van God was voor hem hét homiletisch magazijn. Dat nu nog steeds, in de 21e eeuw, zijn preken gelezen worden, geeft aan dat zijn erfenis een opmerkelijke is. Hij pakte het probleem van de geestelijke dorheid op in een tijd gekenmerkt door het opkomend klimaat van het humanistisch rationalisme. Hofackers prediking geeft weer waar het werkelijk om gaat: Christus alleen. Deze preken laten ook de prediker zelf zien. Zijn stem roept op wat de Reformatie zo na aan het hart lag, en de cadenzen van het sola gratia, sola Scriptura, en het sola fide zijn in elke preek te horen. Het religieuze eigene van Hofacker sluit grote missionaire bewogenheid in. In sermons we cannot disregard the presence of the living God, otherwise preaching will become a performance, without divine authority. Orthodoxy will be gasping for breath when exegesis and dogmatic theology are wholly absorbed in a number of opinions, causing biblical testimony to recede into the background. Ludwig Hofacker (1798–1828, was a preacher who in Bible study and preaching put his ears to the Fountain. The Word of God was his sole homiletic storehouse. Today, in our 21st century, his sermons are still being read. This indicates that he left us a remarkable body of work. He tackled the problem of spiritual dearth in a time of emerging humanistic rationalism. Hofacker’s preaching reflected his core belief: Christ only. His sermons also reflect the preacher himself. His voice clearly recalls what was held so dear in the Reformation, and

  2. Ludwig Edelstein (1902-1965): a German historian of medicine in North American exile and the emergence of the modern Hippocratic Oath.

    Science.gov (United States)

    Pow, Stephen; Stahnisch, Frank W

    2016-11-01

    Already emerging as an original thinker in the field of classical philology and history of medicine, German scholar Ludwig Edelstein became one of many scholars who lost his academic position when the National Socialists came to power in early 1933. This paper details his life before and after his difficult transition from Europe to North America, while reviewing the lasting significance of his translation and commentary on the Hippocratic Oath. © The Author(s) 2015.

  3. «Tiziano?», «Correggio?». Due expertises di Ludwig Baldass e Roberto Longhi nell’archivio di Antonio Morassi

    Directory of Open Access Journals (Sweden)

    Giulio Zavatta

    2017-12-01

    Full Text Available The Photo Archive Antonio Morassi (Ca' Foscari University of Venice contains a unique file with photographs and expertises on two paintings attributed to Titian and Correggio. This paper aims to investigate the role played by the two art historians Ludwig Baldass and Roberto Longhi in this "affair", which represents an evocative case study for the history of Italian art market after the Second World War, and for the critical debate over Correggio and his legacy.

  4. Carl Ludwig's (1847) and Pavel Petrovich Einbrodt's (1860) physiological research and its implications for modern cardiovascular science: translator's notes relating to the English translation of two seminal papers.

    Science.gov (United States)

    Schaefer, Jochen; Lohff, Brigitte; Dittmer, Janke Jörn

    2014-08-01

    Respiratory interactions with the heart have remained a challenging physiological phenomenon since their discovery more than two hundred and fifty years ago. In the course of translating the seminal publications of Carl Ludwig and his disciple Pavel Petrovich Einbrodt into English, we became aware of some under-appreciated aspects of their work that contain useful insights into the history of the phenomenon now called respiratory arrhythmia. Ludwig observed arrhythmic effects of respiratory movements in experiments on dogs and horses and published his findings in 1847. He subsequently undertook further work on this problem, together with Einbrodt. Already in 1847 Ludwig had mentioned an exciting observation on the possible role of mechanical factors of the respiratory movements on the action of the heart in a dog in whom he had artificially induced bouts of coughing. Einbrodt decided to systematically develop methods to increase or decrease the pressure of the air the animal had to breathe. He observed that this procedure led to a greater or lesser degree of compression or decompression of all the organs in the thoracic cavity without apparently causing harmful consequences during the time of its application. How the mechanical influence of breathing affects cardiac activity during respiratory arrhythmia has been the subject of scientific discussions and controversies over a period of more than 150 years and is still unresolved. Recent publications suggest that cardiac mechano-electrical coupling plays an important role in the emergence of cardio-respiratory interdependence. Copyright © 2014 Elsevier Ltd. All rights reserved.

  5. 31st Annual Conference of the Gesellschaft für Klassifikation e.V., Albert-Ludwigs-Universität Freiburg

    CERN Document Server

    Burkhardt, Hans; Schmidt-Thieme, Lars; Decker, Reinhold

    2008-01-01

    Data analysis and machine learning are research areas at the intersection of computer science, artificial intelligence, mathematics and statistics. They cover general methods and techniques that can be applied to a vast set of applications such as web and text mining, marketing, medical science, bioinformatics and business intelligence. This volume contains the revised versions of selected papers in the field of data analysis, machine learning and applications presented during the 31st Annual Conference of the German Classification Society (Gesellschaft für Klassifikation - GfKl). The conference was held at the Albert-Ludwigs-University in Freiburg, Germany, in March 2007.

  6. Täter- und Opfergeschichten. Schuld in Alois Hotschnigs Prosawerken «Aus», «Leonardos Hände» und «Ludwigs Zimmer»

    Directory of Open Access Journals (Sweden)

    Friederike Gösweiner

    2014-05-01

    Full Text Available The assumption this article is based on is that guilt is perhaps the most important theme in Alois Hotschnig’s writing. This article therefore aims at analyzing Hotschnig’s focus on the theme of guilt in his novels. Three examples of Hotschnig’s prose work serve as case studies: his debut Aus, and the two novels Leonardos Hände, and Ludwigs Zimmer. Since guilt seems to be a very important topic in the Austrian literary tradition, this article also tries to establish whether and how Hotschnig takes up this grand Austrian tradition of writing about guilt.

  7. On the history of Ludwig von Bertalanffy's "general systemology", and on its relationship to cybernetics - Part II: Contexts and developments of the systemological hermeneutics instigated by von Bertalanffy

    Science.gov (United States)

    Pouvreau, David

    2014-02-01

    The history of "general system theory" is investigated in order to clarify its meanings, vocations, foundations and achievements. It is characterized as the project of a science of the systemic interpretation of the "real", renamed here "general systemology". The contexts and modes of its elaboration, publication and implementation are discussed. The paper mostly focuses on the works of its instigator: Ludwig von Bertalanffy. However, general systemology was a collective project: the main contributions of other "systemologists", from the 1950s until the 1970s, are hence also considered. Its solidarity with the history of the Society for General Systems Research is notably discussed. A reconstruction of the systemological hermeneutics is undertaken on this basis. It finds out the potential systematic unity underlying the diversity of the contributions to this both scientific and philosophical project. Light is thus shed on the actual scope of von Bertalanffy's works.

  8. Johannes Ludwig Janson, professor of veterinary medicine in Tokyo in 1880-1902 - contribution to German-Japanese medical relations, part IV.

    Science.gov (United States)

    Kast, Alexander

    2010-01-01

    Among the German pioneers of Western medicine in Japan (8, 12) during the Meiji period (1868-1912), veterinary officer Johannes Ludwig Janson (1849-1914) was one of the most important figures. He arrived in Tokyo in October 1880 and taught at the Veterinary School in Komaba. During his tenure, the school in Komaba was integrated into the School of Agriculture of the Imperial University of Tokyo. Numerous of his graduates occupied high public offices. Among his publications, those about domestic animals and veterinary medicine in Japan deserve special attention. He married a Japanese girl and continued teaching in Komaba until 1902. He found his last resting place in Kagoshima, the native place of his wife. To this day, the Japanese consider Janson the founder of modern veterinary medicine in their country.

  9. [The advantage of a modern operational approach to the diagnosis of mental disorders. The case of the Bavarian King Ludwig II--an example from biographical research].

    Science.gov (United States)

    von Zerssen, D

    2013-05-01

    Worldwide discrepancies in the classification, terminology and diagnosis of mental disorders have induced efforts for unification after World War II. This led to the introduction of an operational diagnostic approach according to strict criteria, at the same time taking into account the comorbidity of disorders. However, this approach is still not routinely used. The consequences of this deficiency are demonstrated here by an example from biographical research referring to the Bavarian King Ludwig II. The study is based on an extensive search of the relevant literature. Although the pathography of this Bavarian king is well documented, the diagnoses published between 1910 and 2010 by altogether 21 specialists, are distributed rather chaotically over 24 diagnostic categories of the ICD-10. Merely in the (probably wrong) diagnosis of a schizophrenic psychosis is there agreement among half of the authors. This is concordant with the expert diagnosis of paranoia by von Gudden and his colleagues (1886) when considering the then contemporary concept of the disorder. According to modern diagnostic principles almost half of the 24 diagnoses can be confirmed. The others have to be regarded as false diagnoses. The conclusion is that modern principles of the diagnosis of mental disorders should be applied according to internationally accepted diagnostic manuals. This approach should be used in, but is not exclusive to, biographical research. Precondition is, of course, the exact knowledge and careful application of these principles.

  10. [Requirements for final year medical studies in the era of generation Y - implementation for general and visceral surgery at the Ludwig Maximilians University of Munich].

    Science.gov (United States)

    Albertsmeier, M; Pratschke, S; Raes, P; Werner, J; Angele, M K

    2014-12-01

    The revision of the medical licensing regulations in 2012 has changed the underlying conditions for the practical year (PY), especially in the sense of markedly more flexibility for the medical students. The driving force for these and future changes, however, is not the legislature but rather the students themselves who are explicitly demanding that their training be adapted to their requirements and wishes. Time for the realisation of personal aims, planning of leisure time activities, for the family and social contacts as well as an altogether balanced work-life balance have replaced the wish for professional advancement as premise for the lifestyle of generation Y. Many hospitals, especially the privately-supported, attract students with special offers - university hospitals are called upon to defend their position in the competition for newly qualified students. The present article describes the changes of 2012 as part of a programme for a sustainable increase in the attractivity of the surgical PY at the Ludwig-Maximilian University (LMU) in Munich. Georg Thieme Verlag KG Stuttgart · New York.

  11. [From anamnesis to the art of interpretation, or: What is a "genuine" psychoanalyst? Wolfgang Warda, Ludwig Binswanger, Wilhelm Strohmayer and the origins of psychoanalysis in Thuringia].

    Science.gov (United States)

    May, Ulrike

    2016-01-01

    Warda and Strohmayer from Thuringia were among the first German physicians who developed an interest in Freuds theory and therapeutic method around 1900. Their contributions reflect the influence of Otto Binswanger, professor of psychiatry in Jena, a representative of the "psychological direction" in psychiatry which in the beginning was relatively receptive to Freud. The paper discusses their rapprochement to, and detachment from, the Freudian school, including also the work of a third young physician: Ludwig Binswanger, Otto's nephew, who was active in Jena at the same time. It points to certain factors contributing to the increasing rejection Freud met in academic circles which have been underrated to date: (1) the transformation of psychoanalysis into an art of interpretation; (2) the introduction of transference. Both factors which were elaborated by Freud as essentials of his theoretical and practical approach around 1900 and published in 1904/05, undermined the claim of academic medicine to objectivity. The paper describes how psychoanalysis officially abandoned the scientific standards of contemporary medicine at the Weimar congress in 1911, at the same time as Warda and Strohmayer left the Freudian group.

  12. Ludwig, un roi sur la lune : l’histoire d’un roi fou jouée par des comédien.ne.s en situation de handicap mental

    Directory of Open Access Journals (Sweden)

    Marie Astier

    2017-12-01

    Full Text Available Ludwig, un roi sur la lune, spectacle mis en scène par Madeleine Louarn avec les comédien.ne.s professionnels en situation de handicap mental de l’Atelier Catalyse et présenté lors de la dernière édition du Festival d’Avignon n’est pas une reconstitution historique de la vie de Louis II de Bavière, roi du XIXe siècle diagnostiqué paranoïaque et destitué pour être interné, mais une tentative de transcrire théâtralement la perception du monde d’un homme amoureux de l’Art, de la nature et des hommes, mais qui devait être Roi. Ce n’est ni un personnage ni des comédien.ne.s « handicapé.e.s » que nous sommes invités à voir, mais les visions de Ludwig incarnées par des comédien.ne.s qui se trouvent être en situation de handicap mental. Dans ce spectacle, la « folie » devenue plus tard « handicap mental » apparaît sous les traits de la non-conformité bien plus que sous ceux de la pathologie.

  13. Ludwig Boltzmann, mechanics and vitalism

    International Nuclear Information System (INIS)

    Broda, E.

    1990-01-01

    During most of his life Boltzmann considered classical mechanics, based on the ideas of material points and central forces, as the fundament of physics. On this basis he became one of the founders of Statistical Mechanics, through which thermodynamics was interpreted on an atomistic basis. In this work, Boltzmann was opposed by his colleague, Ernst Mach. Boltzmann also devoted much work to attempts to interpret Maxwell's theory of the electromagnetic field, of which he was a main protagonist in Central Europe, through mechanics. However, as a supporter of mechanics Boltzmann was by no means dogmatic. While he was adamant in his rejection of Wilhelm Ostwald's energism, he was openminded in respect to the relationship of mechanics, electromagnetism and atomistics. Personally, Boltzmann wanted to conserve and transmit the enormous achievements of mechanics, especially in connection with the mechanical theory of heat, so that these results should not be lost to future generations, but he encouraged attempts to proceed in new directions. While within the framework of statistical mechanics the atoms were treated like the material points of classical mechanics, Boltzmann resisted the initial, unwarranted, ideas about the structure and the properties of the atoms. When later valid ideas were evolved, Boltzmann warmly welcomed this progress, without however personally taking part in the new developments. In his later years, Boltzmann took an intense interest in biology. He supported Darwin's theories, and he contributed to them. He may be called an 'absolute Darwinist'. In his search for a natural explanation of the phenomena of life, he used the term 'mechanical', without meaning to limit them to the realm of classical mechanics. This terminological laxity is considered as unfortunate. Extending his application of Darwinian principles to advanced species, including man, Boltzmann put forward 'mechanical' explanations of thought, of morality, of the sense of beauty, and of happiness or unhappiness. 'The god, by whose grace the kings rule, is the fundamental law of mechanics' he said. It is argued now that this impressive but misleading terminology does not justify consideration of Boltzmann as a mechanical materialist. In present terms, Boltzmann was a reductionist rather than a vitalist. He also was one of the founders of evolutionary epistemology. (author)

  14. Die Einführung des "Intensivstudium München" in das Curriculum der Tierärztlichen Fakultät der Ludwig-Maximilians-Universität München [Introducing a clinical rotation system into the curriculum of the Faculty of Veterinary Medicine, Ludwig Maximilians University of Munich

    Directory of Open Access Journals (Sweden)

    Stadler, Oliver

    2008-11-01

    Full Text Available [english] In April 2005, a clinical rotation was introduced in the Faculty of Veterinary Medicine at Ludwig Maximilians University of Munich to improve quality of clinical education. The eigth and ninth semesters were merged into one semester, and the prescribed semester breaks were abandoned. The clinical year was divided into 14 rotations of 3.5 weeks each and included a 3-week break over Christmas and New Year’s. Each clinic offers a range of different rotations among which students have to choose six. Because of the general nature of Germany’s veterinary license, which includes all species and clinical disciplines, students are required to follow certain guidelines while selecting their preferred rotations. For each student, a mandatory 7-week rotation is required in which pathology, food hygiene, and animal welfare is taught. Due to various constraints, the numbers of students admitted to different rotations varies, and therefore not all requests for rotations can be fulfilled. To this end, students are not only asked to indicate their favourite six rotations but also to rank these in order of preference during registration. If demand turns out to exceed the rotations offered, then an alternative rotation is assigned to a student depending on ranked preferences. In an attempt to control quality of new curriculum, student performance is evaluated after each block in nearly all of their rotations. In addition, students are invited to evaluate teachers as well as facilities. [german] Im Sommersemester 2005 wurde an der Tierärztlichen Fakultät der Ludwig-Maximilians-Universität München das „Intensivstudium München“ („Klinische Rotation“ in Form eines Rotationssystems eingeführt. Diese Umstellung hatte die Verbesserung der Qualität der klinischen Ausbildung zum Ziel. Das bisherige achte und neunte Fachsemester wurden zu einem Studienjahr zusammengefasst; die davor übliche Unterteilung in allgemein gültige Vorlesungs- und

  15. Ludwig Boltzmann, Albert Einstein and Franz Joseph

    International Nuclear Information System (INIS)

    Broda, E.

    1983-01-01

    Under the Emperor Francis Joseph (1848-1916) the natural sciences were less weIl supported in Austria than in other countries of Europe. This is explained by the fact that the German speaking middle classes accepted the preeminence of the feudal forces with their antiscientific attitude. The reason for this readiness to subordination was that those middle classes feIt threatened in their relatively favourable situation by Slavs and Latins. Francis Joseph was the typical representative of the aristocracy. Personally, he did his duty conscientiously and was not corrupt, but progressive ideas and scientific thought were alien to him. From his desk he treated Boltzmann benevolently, but he had no wish to meet personally the greatest mind of the Empire or in any respect to ask his views. Another famous subject of the Emperor, Albert Einstein, was apparently ignored altogether. The structural weakness of Austria, due to the national problems, led to immobilism in her scientific life, but also, up to a point, to tolerance. The impression of Victor Adler on Einstein is considered in this historical context. (author) [de

  16. Ludwig Boltzmann, Albert Einstein and Franz Joseph; Ludwig Boltzmann, Albert Einstein und Franz Joseph

    Energy Technology Data Exchange (ETDEWEB)

    Broda, E.

    1983-07-01

    Under the Emperor Francis Joseph (1848-1916) the natural sciences were less weIl supported in Austria than in other countries of Europe. This is explained by the fact that the German speaking middle classes accepted the preeminence of the feudal forces with their antiscientific attitude. The reason for this readiness to subordination was that those middle classes feIt threatened in their relatively favourable situation by Slavs and Latins. Francis Joseph was the typical representative of the aristocracy. Personally, he did his duty conscientiously and was not corrupt, but progressive ideas and scientific thought were alien to him. From his desk he treated Boltzmann benevolently, but he had no wish to meet personally the greatest mind of the Empire or in any respect to ask his views. Another famous subject of the Emperor, Albert Einstein, was apparently ignored altogether. The structural weakness of Austria, due to the national problems, led to immobilism in her scientific life, but also, up to a point, to tolerance. The impression of Victor Adler on Einstein is considered in this historical context. (author) [German] Die Naturwissenschaften wurden in Österreich unter Franz Joseph (1848-1916) weniger gefördert als in anderen Staaten Europas. Dies wird darauf zurückgeführt, daß das deutschsprechende Bürgertum sich mit der Vorherrschaft der feudalen Kräfte abfand, die nicht wissenschafts-freundlich waren. Für die Bereitschaft zur Unterordnung unter die Feudalen war maßgebend, daß das deutschsprechende Bürgertum sich durch Slawen und Romanen in seiner relativen Vorzugsstellung bedroht sah. Franz Joseph war der typische Repräsentant des konservativen Feudalismus. Er war persönlich pflichtbewußt und integer, doch waren ihm fortschrittliche Gedanken und wissenschaftliche Denkweise fremd. Boltzmann behandelte er von seinem Schreibtisch aus wohlwollend, doch hegte er keinen Wunsch, den größten Geist seines Reiches persönlich kennen zu lernen oder ihn in irgendeiner Hinsicht um seine Meinung zu fragen. Von seinem Untertanen Albert Einstein, damals schon sehr berühmt, nahm Franz Joseph offenbar überhaupt kaum Notiz. Die Strukturschwäche Österreichs, die durch die nationalen Probleme bedingt war, führte in seinem wissenschaftlichen Leben zu Immobilismus, aber auch bis zu einem gewissen Grade zu Toleranz. Die Eindrücke Einsteins bei Victor Adler werden in den historischen Zusammenhang gesetzt. (author)

  17. "Fidelio" suurlavastuses astub lavale Ludwig van Beethoven ise / Andres Laasik

    Index Scriptorium Estoniae

    Laasik, Andres, 1960-2016

    2007-01-01

    26. augustil Viinistus esietenduvast Nargen Opera egiidi all valmivast ooperist "Fidelio", lavastaja Liis Kolle. Ooperi autorit kehastavad Peeter Oja, Tarmo Leinatamm, Hannes Võrno. Muusikaline juht Tõnu Kaljuste

  18. ORIGINAL ARTICLE Ludwig's Angina: An Analysis of Sixteen Cases ...

    African Journals Online (AJOL)

    Ogunbodede

    African Journal of oral Health. Volume 2 ... Department of Oral and Maxillofacial Surgery, Faculty of Dentistry, Obafemi Awolwo ... Microbiological investigations showed a polymicrobial nature of the ... cause and duration of infection, clinical.

  19. Ludwig Prandtl and Boundary Layers in Fluid Flow

    Indian Academy of Sciences (India)

    His research is ... research in fluid mechan- ... For common fluids the viscous force is proportional to .... that the analogy is only a very crude, qualitative one. ..... separation is turbulent and the fluid in the wake is nearly stagnant. Method of.

  20. Max Karl Ernst Ludwig Planck (1858-1947

    Directory of Open Access Journals (Sweden)

    Robitaille P.-M.

    2007-10-01

    Full Text Available October 4th, 2007 marks the 60th anniversary of Planck’s death. Planck was not only the father of Quantum Theory. He was also a man of profound moral and ethical values, with far reaching philosophical views. Though he lived a life of public acclaim for his discovery of the Blackbody radiation formula which bares his name, his personal life was beset with tragedy. Yet, Planck never lost his deep faith and belief in a personal God. He was admired by Einstein, not so much for his contributions to physics, but rather, for the ideals which he embodied as a person. In this work, a brief synopsis is provided on Planck, his life, and his philosophical writings. It is hoped that this will serve as an invitation to revisit the philosophical works of the man who, more than any other, helped set the course of early 20th century physics.

  1. How would Ludwig Wittgenstein have performed in the current ...

    African Journals Online (AJOL)

    South African Journal of Higher Education. Journal Home · ABOUT THIS JOURNAL · Advanced Search · Current Issue · Archives · Journal Home > Vol 23, No 4 (2009) >. Log in or Register to get access to full text downloads.

  2. A primazia da natureza ante o espírito em Ludwig Feuerbach The primacy of nature against the spirit in Ludwig Feuerbach

    Directory of Open Access Journals (Sweden)

    Eduardo Ferreira Chagas

    2009-01-01

    Full Text Available O presente artigo pretende destacar a tese de que a natureza para Feuerbach é um existente autônomo e independente e possui primazia ante o espírito. Para ele, a natureza material, que existe, em sua diferencialidade qualitativa, independente do pensar, é diante do espírito o original, o fundamento não deduzível, imediato, não criado, de toda existência real, que existe e consiste por si mesmo. Feuerbach opõe a natureza ao espírito, pois ele a entende não como um puro outro, que só por meio do espírito foi posto como natureza, mas como o primeiro, a realidade objetiva, material, que existe fora do entendimento e é dada ao homem, por meio de seus sentidos, como fundamento e essência de sua vida. Trata-se, pois, primeiro daquela essência (luz, ar, água, fogo, plantas, animais etc. sem a qual o homem não pode nem ser pensado nem existir. A natureza é, para Feuerbach, a pluralidade de todos os objetos e essências que realmente são. Sob esta condição, é possível conceber a natureza como a garantia da exterioridade mesma, como que um existente fora de nós, que nada sabe de si e é em si e por si mesmo; por conseguinte, ela não deve ser vista como aquilo que ela não é, isto é, nem como divina, nem como humana. A natureza sempre existiu, quer dizer, ela existe por si e tem seu sentido apenas em si mesma; ela é ela mesma, ou seja, nenhuma essência mística, pois, por trás dela, não se esconde nenhum absoluto, nada humano, nada divino, transcendental ou ideal.This article tries to delineate the proposition that to Feuerbach nature is an autonomous and independent being that comes first in comparison to the spirit. To him, material nature, that exists in its qualitative differentness, independent from thinking, is the original source, the immediate, not deductible, uncreated fundament of all real existence, that exists and consists in itself, when put vis-à-vis the spirit. Feuerbach sets nature against the spirit, for it is his understanding that nature is not a pure other that only through the spirit was set as nature, but as the first source, the objective material reality that exists outside reason and is given to man by means of his senses as fundament and essence of his life. Therefore, one is dealing first with that essence (light, air, water, fire, plants, animals etc. without which man does not exist or could be thought of as existing. To Feuerbach nature is all objects and essences put together. Under this condition it is possible to conceive nature as guarantor of externality itself as if it could exist independently from us, an entity that is unaware of itself and which exists in itself and by itself; for this reason it shall not be seen as something which it is not, i.e., neither divine nor human. Nature always existed, i.e., it exists in itself and has only meaning in itself; it is itself, i.e., it has no mystical essence, it does not hide behind it any absolute being whether human, divine, transcendental or ideal.

  3. [Remember, Avert, Prevent: Franz Ludwig Berthold Kihn--A Typology of "Euthanasia"].

    Science.gov (United States)

    Braun, B; Frewer, A; Kornhuber, J

    2015-11-01

    The current debate on assisted suicide provides the occasion for calling to mind the role of Berthold Kihn as a psychiatrist under National Socialism. With a historical presentation of a typology of euthanasia, the Academic Psychiatry of Erlangen together with the Medical Ethics would like to sensitize discussions on assisted suicide by drawing attention to the start and end of Kihn's scientific career. Relevant archive material, primary and secondary literature were analyzed and evaluated. As Assistant and Senior Physician at the Psychiatric and Neurological Hospital of the University of Erlangen, Kihn lectured on "the elimination of the inferiors". As Director of the Psychiatric and Neurological Hospital of Jena University, Kihn selected psychiatric patients to be murdered under the "T4 action". Kihn participated in drafting a "Euthanasia Law". Despite his involvement in the murder of mentally ill, Kihn returned to Erlangen as a "Soviet Zone refugee", where a Denazification Court considered him a "hanger-on". Kihn was reintegrated in the academic faculty of the Friedrich-Alexander-University and headed a private clinic. On 21.01.1963, the State's Attorney Nuremberg-Fuerth dropped the criminal procedure against Kihn--officially due to a lack of proof of punishable guilt. An appropriate medical historical contextualization can represent an important condition for an adequate medical ethical debate on physician-assisted suicide and the involvement of psychiatrists. FINAL COMMENT: The analysis of Kihn's patterns of thought and argumentation can help sensitize those involved in debates on physician-assisted suicide and highlights the critical role of psychiatry as a discipline in this context. © Georg Thieme Verlag KG Stuttgart · New York.

  4. Existential analysis and psychoanalysis: specific differences and personal relationship between Ludwig Binswanger and Sigmund Freud.

    Science.gov (United States)

    Bühler, Karl-Ernst

    2004-01-01

    The concise curriculum vitae of the founder of existential analysis is followed by an exact comparison of the polarity (homo natura versus homo cultura) between Binswanger and Freud. Then the five stages in the development of (Existential Daseinsanalysis Analysis) are described: the stage of learning, of practice, of criticism, of the alternative to psychoanalysis, and of reconciliation. The criticism is aimed especially at Freud's naturalism and at the concept of drive. These concepts are opposed by ontoanalytic doctrines derived from Heidegger's ontoanalysis. The differences are further exemplified by the comparison of the existentialanalytical and the psychoanalytical view of the unconscious. A presentation of the treatment of a "hysterical phobia," which is first explained in psychoanalytic terms and later in existentialanalytic terminology (mainly concerning the world-projects) makes the difference between the two schools of thought explicit.

  5. Dwie (antyfilozoficzne „gramatyki” Wittgensteina [Two (anti philosophical grammars of Ludwig Wittgenstein

    Directory of Open Access Journals (Sweden)

    Adam Nowaczyk

    2013-09-01

    Full Text Available Wittgenstein is the author of two conceptions of “grammar”, that were meant to be tools of reaching the same goal: discrediting of the traditional, i.e. “metaphysical” questions of philosophy. His early conception concerns logical grammar being the language of logic notation, which is devoid of logical constants. This idea was supported by the ontological thesis that there are no logical objects. In fact, it was not indispensable for achieving the intended purpose, since the elimination of philosophical problems was provided by the semantic argument that the only sensible statements are those of the natural sciences. The second concept of grammar, presented in the writings of the later Wittgenstein, seems more ambiguous. Grammar is a set of rules of the language game, having a status of grammatical statements. Examples of such statements are diverse, and desirable, according to the authors, reformulation of them all into concrete orders or prohibitions seems problematic. In the Investigations Wittgenstein distinguishes between deep and surface grammar, which serves to determine the proper task of philosophy as description of the deep grammar (especially the grammar of philosophically relevant words. In this sense New Philosophy is a kind of philosophical grammar. Wittgensteinian grammar is also anti-philosophical, as it aims at the elimination of erroneous (pseudometaphysical claims derived from misleading forms of surface grammar. Despite the differences in the concepts of language and grammar in the early and late Wittgenstein, he has not changed his critical approach to the traditional philosophical questions.

  6. Il concetto di medium artistico: Richard Wollheim interprete di Ludwig Wittgenstein

    OpenAIRE

    Maistrello, Andrea

    2016-01-01

    The aim of the dissertation is twofold: (i) analyzing the notion (well known by aestheticians, but not so intensively studied) of artistic medium; (ii) showing the relevance of such notion for aesthetics through the examination of some relevant aspects of Richard Wollheim’s philosophy of art, maybe the main figure in Anglo-American philosophy as for considering artistic medium central in art-theorizing. Artistic media, according to Wollheim, can develop only if properly connected to a cultura...

  7. The Jewish heritage of Ludwig Wittgenstein: its influence on his life and work.

    Science.gov (United States)

    Abramovitch, Henry; Prince, Raymond

    2006-12-01

    This article discusses two aspects of Wittgenstein's Jewish heritage. First, we try to show that Wittgenstein was acutely aware of his own Jewish heritage and especially concerned about its potential influence on his work. Second, we suggest that the form of his work, specifically, his method of inquiry and the peculiar literary character of his work, bear a striking resemblance to that of Hebrew Talmud. Like other assimilated Jews of Central Europe, Wittgenstein may have been directly or indirectly exposed to Hebraic culture and Talmudic logic. An understanding of Wittgenstein's Jewish heritage provides an important and neglected perspective on his work.

  8. How Would Ludwig Wittgenstein Have Performed in the Current South African Higher Education System?

    Science.gov (United States)

    Le Grange, L.

    2009-01-01

    The pressure to perform has migrated from the corporate world into academe. Academics across the globe feel this pressure to perform, often expressed as "publish or perish". I reflect on the rising culture of performativity in recent decades and how it has penetrated South African universities. In doing so, I specifically look at the…

  9. Karl Marx, Ludwig Wittgenstein, and Black Underachievement in the United States and United Kingdom

    Science.gov (United States)

    Tomlin, Carol; Wright, Cecile; Mocombe, Paul C.

    2013-01-01

    This article synthesizes Marxian conceptions of identity construction within capitalist relations of production with the Wittgensteinian notion of "language games" to offer a more appropriate relational framework within which scholars ought to understand the Black-White academic achievement gap in America, the United Kingdom, and…

  10. Star Formation Histories of Local Group Dwarf Galaxies. (Ludwig Biermann Award Lecture 1996)

    Science.gov (United States)

    Grebel, E. K.

    The star formation histories of dwarf galaxies in the Local Group are reviewed. First the question of Local Group membership is considered based on various criteria. The properties of 31 (36) galaxies are consistent with likely (potential) Local Group membership. To study the star formation histories of these galaxies, a multi-parameter problem needs to be solved: Ages, metallicities, population fractions, and spatial variations must be determined, which depend crucially on the knowledge of reddening and distance. The basic methods for studying resolvable stellar populations are summarized. One method is demonstrated using the Fornax dwarf spheroidal galaxy. A comprehensive compilation of the star formation histories of dwarf irregulars, dwarf ellipticals, and dwarf spheroidals in the Local Group is presented and visualized through Hodge's population boxes. All galaxies appear to have differing fractions of old and intermediate-age populations, and those sufficiently massive and undisturbed to retain and recycle their gas are still forming stars today. Star formation has occurred either in distinct episodes or continuously over long periods of time. Metallicities and enrichment vary widely. Constraints on merger and remnant scenarios are discussed, and a unified picture based on the current knowledge is presented. Primary goals for future observations are: accurate age determinations based on turnoff photometry, detection of subpopulations distinct in age, metallicity, and/or spatial distribution; improved distances; and astrometric studies to derive orbits and constrain past and future interactions.

  11. Ernst Ludwig Kirchner´s "Negerplastik" and the mistake of Czech Cubists

    Czech Academy of Sciences Publication Activity Database

    Winter, Tomáš

    2013-01-01

    Roč. 61, č. 4 (2013), s. 356-361 ISSN 0049-5123 Institutional support: RVO:68378033 Keywords : African sculpture * Czech cubism * Primitivism Subject RIV: AL - Art , Architecture, Cultural Heritage http://www.umeni- art .cz/cz/issue-detail.aspx?v=issue-issue-2131

  12. Management of Ludwig's Angina in Pregnancy: A Review of 10 Cases

    African Journals Online (AJOL)

    had stab incisions, under local anesthesia, at the submandibular area bilaterally .... morbidity associated with the use of general anesthesia. We observed two ... trimester of pregnancy and procedures such as dental fillings and scaling and ...

  13. Warfarin-induced sublingual hematoma mimicking Ludwig angina: Conservative management of a potentially life-threatening condition.

    LENUS (Irish Health Repository)

    Cashman, Emma

    2012-02-01

    Sublingual hematoma secondary to excessive anticoagulation is a rare, life-threatening condition. Reports in the literature have emphasized the importance of a prompt reversal of the causative coagulopathy by intravenous administration of vitamin K and fresh frozen plasma. In the event of an unstable airway, surgical intervention via tracheostomy or cricothyroidectomy is advocated. We report a case of sublingual hematoma that was treated conservatively, and we discuss the presentation and management of this entity.

  14. On the history of Ludwig von Bertalanffy's "General Systemology", and on its relationship to cybernetics - part III: convergences and divergences.

    Science.gov (United States)

    Drack, Manfred; Pouvreau, David

    2015-07-04

    Bertalanffy's so-called "general system theory" (GST) and cybernetics were and are often confused: this calls for clarification. In this article, Bertalanffy's conceptions and ideas are compared with those developed in cybernetics in order to investigate the differences and convergences. Bertalanffy was concerned with first order cybernetics. Nonetheless, his perspectivist epistemology is also relevant with regard to developments in second order cybernetics, and the latter is therefore also considered to some extent. W. Ross Ashby's important role as mediator between GST and cybernetics is analysed. The respective basic epistemological approaches, scientific approaches and inherent world views are discussed. We underline the complementarity of cybernetic and "organismic" trends in systems research within the unitary hermeneutical framework of "general systemology".

  15. Discovering the structure of nerve tissue: Part 3: From Jan Evangelista Purkyně to Ludwig Mauthner

    Czech Academy of Sciences Publication Activity Database

    Chvátal, Alexandr

    2017-01-01

    Roč. 26, č. 1 (2017), s. 15-49 ISSN 0964-704X Institutional support: RVO:68378041 Keywords : brain * ganglia * fibers Subject RIV: AB - History OBOR OECD: History (history of science and technology to be 6.3, history of specific sciences to be under the respective headings) Impact factor: 0.633, year: 2016

  16. Arthur Schopenhauer e Ludwig van Beethoven: diálogos possíveis entre música e filosofia

    Directory of Open Access Journals (Sweden)

    Raimundo Rajobac

    2011-01-01

    Full Text Available

    No decorrer do trabalho, procuraremos evidenciar a posição de Schopenhauer sobre os conceitos de Representação e Vontade. Analisaremos sua estética observando a relação hierárquica existente entre as belas artes e a capacidade residente em cada arte de expressão da essência íntima do mundo, chegando à música, como arte que nos transmite o em-si do mundo. Partindo daí, tomaremos como referência o compositor clássico/romântico Beethoven e a “6ª Sinfonia em Fá Maior”, Op. 68-Pastoral, mais especificamente o IV movimento - Tempestade (Gewitter Sturm. Apontaremos, portanto, a ideia de que a obra de arte beethoveniana nos conduz ao que é nomeado por Schopenhauer como sentimento estético e que nos vem sempre através de uma intuição pura, devendo ser interpretado como um sentimento metafísico, uma vez que nele o intelecto atinge o nível de contemplação estética, o que implica o mergulho do sujeito cognoscente dentro do objeto conhecido, ao qual se funde.

  17. Warfarin-induced sublingual hematoma mimicking Ludwig angina: Conservative management of a potentially life-threatening condition.

    LENUS (Irish Health Repository)

    Cashman, Emma

    2011-02-01

    Sublingual hematoma secondary to excessive anticoagulation is a rare, life-threatening condition. Reports in the literature have emphasized the importance of a prompt reversal of the causative coagulopathy by intravenous administration of vitamin K and fresh frozen plasma. In the event of an unstable airway, surgical intervention via tracheostomy or cricothyroidectomy is advocated. We report a case of sublingual hematoma that was treated conservatively, and we discuss the presentation and management of this entity.

  18. On the history of Ludwig von Bertalanffy's "General Systemology", and on its relationship to cybernetics - part III: convergences and divergences

    Science.gov (United States)

    Drack, Manfred; Pouvreau, David

    2015-07-01

    Bertalanffy's so-called "general system theory" (GST) and cybernetics were and are often confused: this calls for clarification. In this article, Bertalanffy's conceptions and ideas are compared with those developed in cybernetics in order to investigate the differences and convergences. Bertalanffy was concerned with first order cybernetics. Nonetheless, his perspectivist epistemology is also relevant with regard to developments in second order cybernetics, and the latter is therefore also considered to some extent. W. Ross Ashby's important role as mediator between GST and cybernetics is analysed. The respective basic epistemological approaches, scientific approaches and inherent world views are discussed. We underline the complementarity of cybernetic and "organismic" trends in systems research within the unitary hermeneutical framework of "general systemology".

  19. Discovering the structure of nerve tissue: Part 3: From Jan Evangelista Purkyně to Ludwig Mauthner.

    Science.gov (United States)

    Chvátal, Alexandr

    2017-01-01

    The previous works of Purkyně, Valentin, and Remak showed that the central and peripheral nervous systems contained not only nerve fibers but also cellular elements. The use of microscopes and new fixation techniques enabled them to accurately obtain data on the structure of nerve tissue and consequently in many European universities microscopes started to become widely used in histological and morphological studies. The present review summarizes important discoveries concerning the structure of neural tissue, mostly from vertebrates, during the period from 1838 to 1865. This review describes the discoveries of famous as well as less well-known scholars of the time, who contributed significantly to current understandings about the structure of neural tissue. The period is characterized by the first descriptions of different types of nerve cells and the first attempts of a cytoarchitectonic description of the spinal cord and brain. During the same time, the concept of a neuroglial tissue was introduced, first as a tissue for "gluing" nerve fibers, cells, and blood capillaries into one unit, but later some glial cells were described for the first time. Questions arose as to whether or not cells in ganglia and the central nervous system had the same morphological and functional properties, and whether nerve fibers and cell bodies were interconnected. Microscopic techniques started to be used for the examination of physiological as well as pathological nerve tissues. The overall state of knowledge was just a step away from the emergence of the concept of neurons and glial cells.

  20. On the history of Ludwig von Bertalanffy’s “General Systemology”, and on its relationship to cybernetics – part III: convergences and divergences

    Science.gov (United States)

    Drack, Manfred; Pouvreau, David

    2015-01-01

    Bertalanffy’s so-called “general system theory” (GST) and cybernetics were and are often confused: this calls for clarification. In this article, Bertalanffy’s conceptions and ideas are compared with those developed in cybernetics in order to investigate the differences and convergences. Bertalanffy was concerned with first order cybernetics. Nonetheless, his perspectivist epistemology is also relevant with regard to developments in second order cybernetics, and the latter is therefore also considered to some extent. W. Ross Ashby’s important role as mediator between GST and cybernetics is analysed. The respective basic epistemological approaches, scientific approaches and inherent world views are discussed. We underline the complementarity of cybernetic and “organismic” trends in systems research within the unitary hermeneutical framework of “general systemology”. PMID:26612966

  1. Ladinia linguistica in una monumentale opera: Atlante linguistico del ladino dolomitico e dei dialetti limitrofi - ALD-1, Dr. Ludwig Reichert Verlag, Wiesbaden 1998

    Directory of Open Access Journals (Sweden)

    Mitja Skubic

    2000-12-01

    Full Text Available L'apparizione dell'atlante linguistico di un territorio romanzo va salutata con gioia, come una festa della ricerca scientifica in tale settore. E il sentimenta di gioia ci pervade quando sfogliamo i primi quattro volumi, in folio, dell 'ALD. Non solo per la mole e l'ampia concezione dell'opera, ma altrettanto e più ancora per il ricco materiale che l' ALD offre. A tutta l' equipe scientifica guidata dal rinomato romanista salisburghese prof. Hans Goebl che assieme a Lois Craffonara é anche ideatore dell 'opera, nonché ai collaboratori e all'editore vadano i nostri sinceri ringraziamenti. Ci sia permesso di aggiungere che la nostra rivista si pregia d'aver potuto ospitare alcuni studi scientifici del prof. Goebl, come anche del suo stretto collaboratore prof. Roland Bauer.

  2. Count Nicolaus Ludwig Von Zinzendorf’s Theory for Missions Portrayed at Herrnhut and by Selected 18th-20th Century Moravian Missions.

    Science.gov (United States)

    1986-01-01

    the progressive methods in advanced missions with churches, schools, gardens, vineyards and orchards, sheep herding, gristmill, cutlery, printing press...pear tree soon became gardens, orchards and vineyards . His success led to Dutch Church and Boer farmer insistence that he leave. Hoping to return, he

  3. Gundula Ludwig, Birgit Sauer, Stefanie Wöhl (Hg.: Staat und Geschlecht. Grundlagen und aktuelle Herausforderungen feministischer Staatstheorie. Baden-Baden: Nomos Verlag 2010.

    Directory of Open Access Journals (Sweden)

    Stefan Schoppengerd

    2010-07-01

    Full Text Available Der Sammelband bietet einen Überblick zu Grundlagen und aktuellen Forschungsgebieten der feministischen Staatstheorie. Aufgezeigt werden wesentliche Analyseinstrumente, die sich aus der feministischen Kritik der Trennung von Öffentlichkeit und Privatheit sowie aus der Auseinandersetzung mit anderen herrschaftskritischen sozialwissenschaftlichen Theorieströmungen ergeben, und ihr Gebrauchswert für verschiedene politikwissenschaftliche Anwendungsgebiete.The collected volume offers an overview of the fundamentals of as well as the most recent research areas for feminist theory of government. It highlights the important analytical tools developed by the feminist critique of the division between public and private as well as by examinations from other social scientific theories also critical of governance. Finally, it points to their applicability to different areas within the political sciences.

  4. Ladinia linguistica in una monumentale opera: atlante lunguistico del ladino dolomitico e dei dialetti limitrofi - ald-1, Dr. Ludwig Reichert Verlag, Wiesbaden 1998.

    Directory of Open Access Journals (Sweden)

    Mitja Skubic

    2015-08-01

    Full Text Available L'apparizione dell'atlante linguistico di un territorio romanzo va salutata con gioia, come una festa della ricerca scientifica in tale settore. E il sentimento di gioia ci pervade quando sfogliamo i primi quattro vol umi, in folio, deli' ALD. Non sol oper la mole e l'ampia concezione dell'opera, ma altrettanto e più ancora per il ricco materiale che l 'ALD offre. A tutta l' équipe scientifica guidata dal rinomato romanista salisburghese prof. Hans Goebl che assieme a Lois Craffonara e anche ideatore deli' opera, nonché ai collaboratori è all'editore vadano i nostri sinceri ringraziamenti. Ci sia permesso di aggiungere che la nostra rivista si pregia d'aver potuto ospitare alcuni studi scientifici del prof. Goebl, come anche del suo stretto collaboratore prof. Roland Bauer.

  5. "Intelligence and Civilisation": A Ludwig Mond Lecture Delivered at the University of Manchester on 23rd October 1936 by Godfrey H. Thomson. A Reprinting with Background and Commentary

    Science.gov (United States)

    Deary, Ian J.; Lawn, Martin; Brett, Caroline E.; Bartholomew, David J.

    2009-01-01

    Here we reprint, and provide background and a commentary on, a recently-rediscovered lecture by Godfrey H. Thomson entitled, "Intelligence and civilisation." It was delivered at the University of Manchester, UK, on 23rd October, 1936, printed in 1937 in the short-lived "Journal of the University of Manchester" and as a pamphlet…

  6. Energy-oriented modernisation of prefabricated residential buildings in East Germany, illustrated by the example of large-panel buildings at Weimar, Ludwig-Feuerbach-Str. 10-18; Energetische Sanierung des industriell errichteten Wohnungsbaus in den neuen Bundeslaendern am Beispiel der Grossblockbauweise in Weimar, Ludwig-Feuerbach-Str. 10 bis 18

    Energy Technology Data Exchange (ETDEWEB)

    Reiss, J.; Erhorn, H. [Fraunhofer-Institut fuer Bauphysik, Stuttgart (Germany); Augner, R.; Warnstedt, K. [Weimarer Wohnstaette GmbH, Weimar (Germany); Nitschke, S.; Wenzel, P. [Architektengemeinschaft Nitschke-Donath, Weimar (Germany)

    1997-12-31

    The demonstration object with 40 residential units is described in the condition prior to its redevelopment. The parts of the redevelopment concept dealing with energy conservation and design are discussed in detail. Further, the execution of the construction work and the measurements necessary to make a thermal and energetic analysis of the building are described. In tabulated form, heat energy consumption quantities are listed as a function of space air temperature. Similarly, the cost of redevelopment and area-specific costs of the thermal insulation systems installed at the building are indicated. (MSK) [Deutsch] Das Demonstrationsobjekt mit 40 Wohnungen wird in seinem Zustand vor der Sanierung beschrieben. Die energetischen Massnahmen des Sanierungskonzepts sowie gestalterische Massnahmen werden naeher erlaeutert. Weiter werden die Bauausfuehrung und die fuer die thermische und energetische Gebaeudeanalyse notwendigen Messungen beschrieben. Tabellarische werden die Heizwaermeverbraeuche in Abhaengigkeit von der Raumlufttemperatur aufgezeigt. Ebenso sind die Kosten fuer die Sanierung sowie die flaechenspezifischen Kosten fuer die am Gebaeude ausgefuehrten Daemmsysteme aufgefuehrt.

  7. EUROPE: Swiss role

    International Nuclear Information System (INIS)

    Anon.

    1995-01-01

    its distinguished professors. Modern Swiss theoretical research groups cultivate numerous international links and collaborations. Many projects are now in part funded by the European Commission's programmes. The main groups are in Bern, Geneva and ETH-Zurich. Permanent positions are almost restricted to full professors (only about one fourth of the theorists).There are hardly any permanent positions at an intermediate level. Playing an important national role is the ''Forum of Swiss High Energy Physicists'' (Chairman, Ludwig Tauscher), which reports to the Federal Office for Education and Science. Support for LHC emerged at an early stage, and about 60 academic staff have signed LHC proposals. With such a strong community, Swiss groups do not concentrate on a single LHC detector. However financing of the LHC detectors and the related R&D work might call for some additional funding

  8. Marxova filosofická antropologie

    Czech Academy of Sciences Publication Activity Database

    Landa, Ivan

    2015-01-01

    Roč. 63, č. 3 (2015), s. 339-355 ISSN 0015-1831 Institutional support: RVO:67985955 Keywords : Karl Marx * Ludwig Feuerbach * Ludwig Wittgenstein * human nature * anthropological difference * species being * life form * alienation Subject RIV: AA - Philosophy ; Religion

  9. Advanced Space Propulsion Study - Antiproton and Beamed Power Propulsion

    Science.gov (United States)

    1987-10-01

    H. Koch, A. Kreissl, H. Poth, U. Raich, D. Rohmann, C. Backenstoss, Ch. Findeisen , J. Repond, L. Tauscher, A. Nilsson, S. Carius, M. Suffert, S...Backenstcss, I. Bergstr8m, S. Carius, S. Chj&rLlambous, M.D. Cooper, Ch. Findeisen , D. Hatsifotiadou, M. Hugi, A. Kerek, H.O. Meyer, P. Pavlopoulos, J. Repond...Chjaralambous, M.D. Cooper, Ch. Findeisen . D. Hatzifotiadou, M. Hugi, A. Kerek, H.O. Meyer, P. Pavlopoulos, J. Repond, L. T&uscher, D. Tr8ster, M.C.S

  10. A Fatal Fad? Tongue Studs Cause More Problems Than Chipped Teeth

    Science.gov (United States)

    ... a fatal infection, such as Ludwig's angina or endocarditis, according to a report in the May/June 2004 issue of General Dentistry , the Academy of General Dentistry's (AGD) clinical, peer-reviewed journal. Ludwig's angina, a bacterial infection of the floor of the mouth, occurs ...

  11. Culture as a monastic rule

    DEFF Research Database (Denmark)

    Albinus, Lars

    2018-01-01

    A conference paper about Peter Sloterdijk's erratic interpretation of the philosophy of Ludwig Wittgenstein as an example of cultural elitism.......A conference paper about Peter Sloterdijk's erratic interpretation of the philosophy of Ludwig Wittgenstein as an example of cultural elitism....

  12. Modeling Trans-Scale Social Processes

    Science.gov (United States)

    2010-05-01

    community as an ecology of games • Ludwig Wittgenstein , 1958 – Philosophical investigations • Harold Garfinkel, 1963 – A concept of, and experiments with...and realize qualitative game insights Multigame interactions Ludwig Wittgenstein . Family Resemblances among Games • Consider the proceedings

  13. « New Persian glosses in East Syriac texts of the eighth to tenth centuries », in : Ludwig Paul, ed., Persian origins: Early Judaeo-Persian and the emergence of New Persian: collected papers of the symposium, Göttingen 1999. Wiesbaden, Harrassowitz,

    OpenAIRE

    Rédaction,

    2007-01-01

    Study of twenty-five Persian glosses, including some hapax legomena, that are contained in three East-Syriac commentaries on the Pentateuch and show southwestern dialectal features contrasting with the northeastern ones of Classical New Persian in Arabic script.

  14. Die Umsetzung der Leitlinien für Fakultäts-interne Leistungsnachweise am Lehrbereich Allgemeimedizin der Ludwig-Maximilians-Universität (LMU München [Realisation of the guidelines for faculty-internal exams at the Department of General Medicine at the University of Munich

    Directory of Open Access Journals (Sweden)

    Boeder, Niklas

    2012-05-01

    Full Text Available [english] Graded exams are prerequisites for the admission to the medical state examination. Accordingly the exams must be of good quality in order to allow benchmarking with the faculty and between different universities. Criteria for good quality need to be considered - namely objectivity, validity and reliability. The guidelines for the processing of exams published by the GMA are supposed to help maintaining those criteria. In 2008 the Department of General Medicine at the University of Munich fulfils only 14 of 18 items. A review process, appropriate training of the staff and the introduction of the IMSm software were the main changes that helped to improve the ‘GMA-score’ to 30 fulfilled items. We see the introduction of the IMSm system as our biggest challenge ahead. IMSm helps to streamline the necessary workflow and improves their quality (e.g. by the detection of cueing, item analysis. Overall, we evaluate the steps to improve the exam process as very positive. We plan to engage co-workers outside the department to assist in the various review processes in the future. Furthermore we think it might be of value to get into contact with other departments and faculties to benefit from each other’s question pools.[german] Benotete Prüfungen sind Voraussetzung für die Zulassung zum zweiten Abschnitt der Ärztlichen Prüfung (Staatsexamen in der Medizin. Daraus lässt sich die Notwendigkeit ableiten, qualitativ hochwertige Prüfungen zu konzipieren, die einen Leistungsvergleich unter Absolventen einer Fakultät und darüber hinaus auch interfakultär erlauben. Hierbei sind Kernqualitätsmerkmale Objektivität, Validität und Reliabilität zu beachten. Die im Leitlinienkatalog der GMA genannten Kriterien sollen die Qualität der Prüfungen sicherstellen. Das Prüfungskonzept des Lehrbereichs Allgemeinmedizin an der LMU erreichte bei Betrachtung der MC-Klausur 2008 nur 14 von 48 möglichen Kriterien. Ein fest eingeplanter Review-Prozess, stetige Weiterbildung des Prüfungsverantwortlichen und die Einführung der Prüfungsverwaltungssoftware IMSm waren Kernpunkte der Veränderung. Heute liegen die Anzahl der erreichten GMA-Kriterien bei 30. Besonders die Einführung der Prüfungsverwaltungssoftware IMSm wurde als zukunftsweisend betrachtet. Die eingebauten Review-Elemente des Systems erleichtern die Etablierung dieser Prozesse und erhöhen die Qualität der Fragen (Item-Analyse, Erkennung von Cueing und weiteren Problemen im Review-Prozess. Die aktuellen Verbesserungsmaßnahmen sind im Sinne einer Qualitätssicherung der Prüfungen als sehr positiv zu bewerten. Es erscheint erstrebenswert, den Kontakt zu Prüfungsverantwortlichen anderer Fakultäten zu suchen, um durch Vernetzung der gegenseitigen Fragepools zu profitieren.

  15. Coating with fungicide and different doses of fertilizer in vinhatico ...

    African Journals Online (AJOL)

    Lucas

    2016-09-21

    Sep 21, 2016 ... The treatments were: seed coating with sand + lime + fungicide with different doses of .... The index was calculated based on the formula of Maguire (1962). ..... Ludwig EJ, Nunes UR, Mertz LM, Silva JR, Nunes SCP (2014).

  16. Liberalismusest / Heido Vitsur

    Index Scriptorium Estoniae

    Vitsur, Heido, 1944-

    2008-01-01

    Liberalismist seoses eesti keeles ilmunud Ludwig von Misese raamatuga "Liberalism". Artikli autor oletab, et lähiaastail ei oota meid ees liberalismi positsioonide tugevnemine, vähemalt majanduses mitte

  17. Kas tehnika on tähtis? / Ingrid Sahk

    Index Scriptorium Estoniae

    Sahk, Ingrid, 1976-

    2016-01-01

    Friedrich Ludwig von Maydelli Baltimaade ajaloopiltide graafikatehnilisest taustast: kas Maydell rakendas graafikaloomingus oforti või vasegravüüri, millised võimalused olid tal 19. sajandi alguses ja milline oli tema graafikaalane ettevalmistus

  18. Pompejanum Tartu Ülikooli Kunstimuuseumis : üks haruldane interjöörinäidis / Inge Kukk

    Index Scriptorium Estoniae

    Kukk, Inge

    2003-01-01

    Pompeji stiilis 19. saj. ruumikujunduse parim näide Eestis. Antiikaja seinamaali motiivide kasutamisest. Töid alustati 1868. aastal. Tartu maalermeister F. Redlin, juhendas antiikarheoloog Ludwig Schwabe

  19. Moments in the Modern History of the Language Sciences.

    Science.gov (United States)

    Swales, John M.

    1999-01-01

    Discusses the beginning of the ascendancy of the language sciences in the past 50 years to become the "queen" of social studies. Focuses on contributions by Mikhail Bakhtin, Ludwig Wittgenstein, Noam Chomsky, Erving Goffman, and Michael Halliday. (SC)

  20. The Rudiments of Language.

    Science.gov (United States)

    Canfield, John V.

    1995-01-01

    Discusses the question of whether nonhuman species, such as apes, possess rudimentary language, focusing on the ideas of Ludwig Wittgenstein and Noam Chomsky in regard to the development of oral language in young children and apes. (51 references) (MDM)

  1. THE JU-LMU LINK FOR MEDICAL EDUCATION: EXCHANGING ...

    African Journals Online (AJOL)

    Anke Wanger, Minas Woldetsadik, Matthias Siebeck

    Jimma University (JU) in Ethiopia and Ludwig-Maximilians-University (LMU) in ... For the future we plan to integrate Ethiopian students coming to LMU ... travelling to Germany for becoming PBL tutors will participate in LMU's regular PBL-.

  2. Piccolo tänab suupilli leiutajat

    Index Scriptorium Estoniae

    2005-01-01

    Suupilliklubi Piccolo kontserdist 17. juunil Pärnu Lastepargis, mis on pühendatud Saksa pillimeistrile Christian Friedrich Ludwig Buschmannile. Pärnu neljandast rahvusvahelisest suupillifestivalist "Baltic-Nordic Harmonica"

  3. Madkultur i skolen

    DEFF Research Database (Denmark)

    Brock, Steen; Christensen, Anne-Marie Søndergaard

    2016-01-01

    Artiklen belyser etiske problemstillinger omkrig dette at spise i skoletiden, på baggrund af Jürgen Habermas og Ludwig Wittgensteins respektive moralopfattelser. I særlig grad tematiseres forholdet mellem medborgerskab og verdensborgerskab, samt etikkens eksistentielle dimensioner...

  4. Fern- und Fehlzündungen. Bedenken zu Ingeborg Bachmanns Wittgenstein-Rezeption / Georg Gimpl

    Index Scriptorium Estoniae

    Gimpl, Georg, 1949-

    2007-01-01

    Ettekanne Ingeborg Bachmanni 80. sünniaastapäevaks pühendatud rahvusvaheliselt konverentsilt Tartus 12.-13. aprillil 2006. aastal. Wittgensteini retseptsioonist Bachmanni loomingust Ludwig Wittgensteini "Loogilis-filosoofilise traktaadi" põhjal (Tartu : Ilmamaa, 1996)

  5. Sigtuna Think Piece 5

    African Journals Online (AJOL)

    developed an approach inspired by the later works of Ludwig Wittgenstein ... A moral reaction is a personal, immediate, spontaneous emotional reaction that ... call rational ideas and thoughts about moral reactions, moral dilemmas or moral.

  6. Firiedrich Hübbe mõistatus / Mart Siilivask

    Index Scriptorium Estoniae

    Siilivask, Mart, 1966-

    2013-01-01

    Tartus tegutsenud Friedrich Hübbest ja Tallinnas tegutsenud Friedrich Ludwig Theodor Hübbest. Tartus tegutsenud Friedrich Hübbe sai 1873. aastal raelt heakskiidu iseseisva ehitusettevõtte rajamiseks. 1877. aastal sai ta loa rajada Emajõe ja Kroonuaia tänava nurgakrundile aurusaeveski. See mees pole seotud Tallinna ehitusäriga. Tallinnas tegutses teine Mecklenburgist pärit ehitusmeister - Friedrich Ludwig Theodor Hübbe, kes asutas 1907. aastal Toompuiestee 10 oma ehitusettevõtte

  7. Wittgenstein mellem tro og tvivl

    DEFF Research Database (Denmark)

    Rigtrup, Diana

    På baggrund af filosoffen Ludwig Wittgensteins (1889-1951) dagbogsoptagelser fra 1930-erne beskriver forfatteren hans tilgang til religionen, der synes at have befundet sig på et knivsæg mellem tro og tvivl......På baggrund af filosoffen Ludwig Wittgensteins (1889-1951) dagbogsoptagelser fra 1930-erne beskriver forfatteren hans tilgang til religionen, der synes at have befundet sig på et knivsæg mellem tro og tvivl...

  8. Karl Valentin’s Illogical Subversion: issues arising from Karl Valentin’s Das Aquarium and Liesl Karlstadt’s Verein der Katzenfreund

    OpenAIRE

    Wilson, Mike; Double, Oliver

    2003-01-01

    Valentin Ludwig Fey was born on 4 June 1882 in the Munich suburb of Au, effectively the only child of an artisan-class family – his sister and two brothers all died in early childhood before Valentin Ludwig was even six months old. Valentin himself only narrowly survived a childhood encounter with diptheria (all of which, perhaps unsurprisingly, contributed to his ever-increasing hypochondria1), but he went on to become Karl Valentin, arguably the most famous German comedian and cabaret perfo...

  9. Ztvárnění přírody ve vybraných pohádkách ve sbírce Phantasus od Ludwiga Tiecka

    OpenAIRE

    Böhmová, Ellen

    2011-01-01

    The representation of the nature in the chosen fairy tales from the collection Phantasus by Ludwig Tieck. This thesis deals with the depiction of nature which played an important role in German literature of the early Romanticism. The analysis is based on three fairytales from Phantasus by Ludwig Tieck, namely, on two »nature tales« Der blonde Eckbert and Der Runenberg and one later tale Die Elfen. The thesis is divided into two main parts. The first one-theoretical, introduces the author of ...

  10. Riflessioni sulla ricezione di Goldoni nel '700 francese

    DEFF Research Database (Denmark)

    Olsen, Michel

    2011-01-01

    This essay takes up the relative incomprehension experienced in France by Goldoni, as before him by the great Dano-norwegian comedy-writer Ludwig Holberg. An exception was Élie Fréron, known as the antagonist of the philosophes, but rediscovered in the last decades of the last century as a brilli......This essay takes up the relative incomprehension experienced in France by Goldoni, as before him by the great Dano-norwegian comedy-writer Ludwig Holberg. An exception was Élie Fréron, known as the antagonist of the philosophes, but rediscovered in the last decades of the last century...

  11. The CAWMSET Report: A Framework for Change

    Science.gov (United States)

    Budil, Kimberly S.

    2001-04-01

    In October 1998 the Commission on the Advancement of Women and Minorities in Science, Engineering and Technology Development (CAWMSET) was established by Congress through legislation developed and sponsored by Congresswomen Constance A. Morella (R-MD). The CAWMSET became a focal point for a grass-roots organization of women at the Lawrence Livermore National Laboratory (LLNL) and Sandia National Laboratories (SNL), California in collaboration with the Society of Women Engineers seeking to improve the environment in our workplaces. With the encouragement of our Congresswoman, Ellen Tauscher (D-CA), we embarked on an effort to provide input to the Commission regarding the recruitment, advancement and retention of women in the technical workforce since the input they received was primarily focused on the educational pipeline. The release of the CAWMSET's final report this summer provided a framework to begin to work toward the overarching goal of an inclusive, supportive, and diverse scientific community and to help us devise strategies for our home organizations that will allow us to achieve this in the near future. The Commission's final recommendation was to create a follow-on organization to carry their work forward. Professional organizations like the American Physical Society can play a key role in helping to ensure that the CAWMSET report is acted upon, not filed and forgotten. I will discuss the findings of the CAWMSET as well as past and ongoing activities at LLNL and SNL in support of this effort.

  12. Sediment yield assessment in the Upper Wadi Kebir catchment ...

    African Journals Online (AJOL)

    Soil erosion that occurs within fluvial basins has a significant impact on ... Regarding the sediment rating models, Walling and Webb [27], Ludwig and ... The climate over the study area is Mediterranean with dry summers and .... collected data set and therefore a high scatter of the cloud around the regression line (Fig. 3).

  13. Resonance – Journal of Science Education | Indian Academy of ...

    Indian Academy of Sciences (India)

    Home; Journals; Resonance – Journal of Science Education; Volume 10; Issue 12. Ludwig Boltzmann and Entropy. Sriram Ramaswamy. Volume 10 Issue 12 December 2005 pp 176-178. Fulltext. Click here to view fulltext PDF. Permanent link: https://www.ias.ac.in/article/fulltext/reso/010/12/0176-0178. Author Affiliations.

  14. Quantitative Voxel-to-Voxel Comparison of TriBeam and DCT Strontium Titanate Three-Dimensional Data Sets (Postprint)

    Science.gov (United States)

    2015-02-09

    materials such as alumina (Gonzalez et al., 2013), titanium (King et al., 2010) and aluminium (Ludwig, King et al., 2009). 2.1.2. TriBeam data collection...nickel alloys (Echlin, Lenthe et al., 2014), and geological samples (Echlin et al., 2015). The strontium titanate sample was serially sectioned in the

  15. Entropy in Biology

    Indian Academy of Sciences (India)

    During the process of ageing, the balance shifts in the direction of anarchy. Death is ... tion of life and the laws of statistieal physics and entropy, both of which ... capable of doing work. ... defined by Ludwig Boltzmann in 1877, the entropy of the.

  16. 76 FR 41816 - Notice of Intent To Prepare an Environmental Impact Statement for the Proposed Ocotillo Sol Solar...

    Science.gov (United States)

    2011-07-15

    ...] Notice of Intent To Prepare an Environmental Impact Statement for the Proposed Ocotillo Sol Solar Project... (ROW) authorization request for the Ocotillo Sol Solar Energy Facility (Project), a 15-18 megawatt (MW... Ocotillo Sol Solar Project by any of the following methods: Mail: Noel Ludwig, California Desert District...

  17. Religion as a philosophical matter

    DEFF Research Database (Denmark)

    Albinus, Lars

    with groundbreaking thoughts about culture and a basic human 'conditionality' among interwar philosophers such as Ernst Cassirer, Ludwig Wittgenstein, Walter Benjamin, and Martin Heidegger. Finally it draws a line to Jean-Luc Nancy’s deconstruction of Christianity which can also be seen as a deconstruction...

  18. See This Sound

    DEFF Research Database (Denmark)

    Kristensen, Thomas Bjørnsten

    2009-01-01

    Anmeldelse af udstillingen See This Sound på Lentos Kunstmuseum Linz, Østrig, som markerer den foreløbige kulmination på et samarbejde mellem Lentos Kunstmuseum og Ludwig Boltzmann Institute Media.Art.Research. Udover den konkrete udstilling er samarbejdet tænkt som en ambitiøs, tværfaglig...

  19. Oe-ce-m

    Indian Academy of Sciences (India)

    Ludwig Prandtl is considered to be the founder of modem fluid mechanics. He, like Newton ... in fluid mechanics. According to the theory, for fluids with small viscosity, like air and water, viscous ... sky left behind by an airplane. In high speed ...

  20. Den filosofiske krimi. Med særligt fokus på Henning Mortensens Sondrup-trilogi

    DEFF Research Database (Denmark)

    Hansen, Kim Toft

    2008-01-01

    Når man starter en roman med et citat af filosoffen Ludwig Wittgenstein, er tonen allerede slået an. Lader man dernæst en mand finde dolket, bliver det hurtigt tydeligt, hvor vi befinder os: kriminalromanens sprossede skygge. Men hos den danske forfatter Henning Mortensen falder skyggerne på en...

  1. A patriotic 'Picture Gallery' or a Universal 'Tree of Knowledge'? Metaphors of Knowledge in the Historia Litteraria Works

    Czech Academy of Sciences Publication Activity Database

    Smyčka, Václav

    2016-01-01

    Roč. 139, 1/2 (2016), s. 25-49 ISSN 0024-4457 R&D Projects: GA ČR GAP406/12/2254 Institutional support: RVO:67985955 Keywords : Nikolaus Adaukt Voigt * Ignaz Born * Franz Martin Pelzel * Ludwig Zehnmark * metaphor * knowledge * temporality Subject RIV: AB - History

  2. The Concept of Design: Are We off Track?

    Science.gov (United States)

    2012-06-15

    Andrews, Henry Mintzberg, Ludwig von Bertalanffy, Thomas Kuhn, Horst Rittel, Melvin Webber, Dietrich Dörner, and Peter Senge listed below cement a...perspective. The terms, concepts, and intellectual accessories presented in this chapter cement a deeper appreciation and understanding of design as a...thinking. Creative thinking involves generating something new or original. It involves the skills of flexibility, originality, fluency , elaboration

  3. Raikülast saab Eesti mõisate süda / Imbi Raikna

    Index Scriptorium Estoniae

    Raikna, Imbi

    2004-01-01

    Raikküla mõisa ajaloost, omanikest. Mõisahoone arhitektiks arvatakse olevat Johann Carl Ludwig Engel. Raikküla mõisa tegi kuulsaks Keyserlingide suguvõsa. 1999. a. omandas mõisa perekond Jõesoo, kes on hüljatud valduse ellu äratanud, kavandades sinna raamatumõisa ja mõisainfo keskust. 10 ill

  4. Hip, Hip, Soret!

    Science.gov (United States)

    Müller-Plathe, Florian

    Many years ago, Ludwig did detect the behaviour now called the Soret effect. Sodium sulphate in eighteen-fifty-six did not obediently follow Fick's first law. But if he cooled down one side the salt went left, the water to the right. He was surprised in every way. Hip, hip, Soret!

  5. The Statistical Interpretation of Entropy: An Activity

    Science.gov (United States)

    Timmberlake, Todd

    2010-01-01

    The second law of thermodynamics, which states that the entropy of an isolated macroscopic system can increase but will not decrease, is a cornerstone of modern physics. Ludwig Boltzmann argued that the second law arises from the motion of the atoms that compose the system. Boltzmann's statistical mechanics provides deep insight into the…

  6. Saaremaa murrakutest 18. sajandil / Eberhard Winkler

    Index Scriptorium Estoniae

    Winkler, Eberhard

    2008-01-01

    Kahest vanemast Saaremaalt pärit keelenäitest: Schlözer, August Ludwig. Gesammelte Nachrichten von den Ueberresten der Liven, in Livland und Kurland. (1770) ja Kruse, Friedrich Karl Hermann. Ur-Geschichte des Esthnischen Volksstammes und der Kaiserlich Russischen Ostseeprovinzen ... (1846)

  7. Fulltext PDF

    Indian Academy of Sciences (India)

    International Conference on Algebra and. Geometry. BOOK REVIEWS. 106 Atomic Warrior. Shobhana Narasimhan. Front Cover. 110. 110. 111. 112 n3. Bonnet macaque (See classroom article Project Ufescape on The Macaques of India, page 94.) Back Cover. (Picture courtesy: Anindya Sinha). ludWig Eduard Boltzmann.

  8. Sano, kuracado, higieno (health, medicine, hygiene): ophthalmologists and Esperanto.

    Science.gov (United States)

    Ohry, Avi

    2014-01-01

    Historically, some ophthalmologists were closely associated with the constructed language Esperanto. These include the founder of the language Ludwig Lazar Zamenhof (1859-1917), his son Leon, Max Talmud (1869-1941), Kazimierz Bein (1872-1959), and Louis Emile Javal (1839-1907).This paper considers the role of these ophtalmologists who attempted to create international languages, whether oral, written or musical.

  9. Skating in a Life Context: Examining the Significance of Aesthetic Experience in Sport Using Practical Epistemology Analysis

    Science.gov (United States)

    Maivorsdotter, Ninitha; Wickman, Per-Olof

    2011-01-01

    The purpose of this article is to suggest and illustrate a methodological approach for studies of learning in physical education (PE) and sport pedagogy in order to investigate and clarify the relation between how people learn and the settings or context in which they learn. Drawing on the work of John Dewey, the later works of Ludwig Wittgenstein…

  10. RDX in Plant Tissue: Leading to Humification in Surface Soils

    Science.gov (United States)

    2013-01-01

    distribution, and transfor- mation of TNT in higher plants. Ecotoxicology and Environmental Safety 64(2): 136–145. Amann, R. I., W. Ludwig, and K.-H...Schleifer. 1995. Phyolgenetic identification and in situ detection of individual microbial cells without cultivation . Microbiol. Rev. 59: 143–169

  11. Ludvík Rittersberk: Die Brüder Edice a překlad libreta Jaroslav ze Šternberka a bitva s Tatary u Olomouce v operním hávu

    Czech Academy of Sciences Publication Activity Database

    Fránek, Michal; Kopecký, J.; Reittererová, V.

    2017-01-01

    Roč. 54, č. 1 (2017), s. 25-70 ISSN 0018-7003 Institutional support: RVO:68378068 Keywords : Ludvík Rittersberk (Ludwig Ritter von Rittersberg) * opera * libretto * Jaroslav ze Šternberka * Dvůr Králové Manuscript Subject RIV: AJ - Letters, Mass-media, Audiovision OBOR OECD: Specific literatures

  12. Darshana Jolts

    Indian Academy of Sciences (India)

    Only by the second half of 19th century did it become clear that the difference between ... Boltzmann law, discovered in 1879 by Josef Stefan and in 1884 by Ludwig Boltzmann. ... occur without input from or output to the outside is known as the principle of ... rich chapter of physics, known as the kinetic theory of heat 11.

  13. A Behavioral Treatment for Traumatic Brain Injury-Associated Visual Dysfunction Based on Adult Cortical Plasticity

    Science.gov (United States)

    2014-12-01

    Zomet, Lev, Yehezkel, Sterkin & Levi, 2012b) and developmental object and face agnosia (Lev, Gilaie-Dotan, Gotthilf-Nezri, Yehezkel, Brooks, Perry...followed by mid-level perceptual improvements in developmental object and face agnosia . Dev Sci, Lev, M., Ludwig, K., Gilaie-Dotan, S., Voss, S

  14. South African Journal of Geomatics, Vol. 5, No. 2, September 2016

    African Journals Online (AJOL)

    asd

    Fred Cawood. The remote sensing theme consisted of two papers. Cilence Munghemezulu, Ludwig Combrinck, Joel Botai and Zinhle Mashaba mapped multipath as part of the site investigation for the installation of a timing antenna for lunar laser ranging applications at the Hartebeesthoek Radio Astronomy Observatory.

  15. Annals of Medical and Health Sciences Research - Vol 4, No 3 (2014)

    African Journals Online (AJOL)

    Management of Ludwig's angina in pregnancy: a review of 10 cases · EMAIL FREE FULL TEXT EMAIL FREE FULL TEXT DOWNLOAD FULL TEXT DOWNLOAD ... Role of systemic markers in periodontal diseases: a possible inflammatory burden and risk factor for cardiovascular diseases? EMAIL FREE FULL TEXT EMAIL ...

  16. African Health Sciences - Vol 7, No 1 (2007)

    African Journals Online (AJOL)

    Katz method: microscopical appearance of the helminth eggs · EMAIL FREE FULL TEXT EMAIL FREE FULL TEXT · DOWNLOAD FULL TEXT DOWNLOAD FULL TEXT. E I Odongo-Aginya, K Narcis, S Ludwig, H Wabinga, A Fenwick, A Montresor ...

  17. 77 FR 40859 - Gulf of Mexico Fishery Management Council; Public Meetings; Correction

    Science.gov (United States)

    2012-07-11

    ... DEPARTMENT OF COMMERCE National Oceanic and Atmospheric Administration Gulf of Mexico Fishery.... SUMMARY: The Gulf of Mexico Fishery Management Council (Council) will convene its Law Enforcement Advisory... Ludwig Lane, Grand Isle, LA 70358; telephone: (985) 787-2163 Council address: Gulf of Mexico Fishery...

  18. Book reviews

    NARCIS (Netherlands)

    NN,

    2002-01-01

    It took a long time to produce, but eventually early in 2001 the first part of this extensive compendium of macromycetes appeared. It is the result of decades of work by the author, who is known as a passionate mushroom collector and painter. Ludwig has the special gift that he is able to record the

  19. Training and "Abrichtung": Wittgenstein as a Tragic Philosopher of Education

    Science.gov (United States)

    Friesen, Norm

    2017-01-01

    As a landmark philosopher of language and of mind, Ludwig Wittgenstein is also remarkable for having crossed, with apparent ease, the "continental divide" in philosophy. It is consequently not surprising that Wittgenstein's work, particularly in the "Philosophical Investigations," has been taken up by philosophers of education…

  20. Differentially Positioned Language Games: Ethnomathematics from a Philosophical Perspective

    Science.gov (United States)

    Knijnik, Gelsa

    2012-01-01

    This paper discusses a new philosophical perspective for ethnomathematics which articulates Ludwig Wittgenstein's and Michel Foucault's theoretical notions. It is conceived as a theoretical toolbox which allows the analysis of, on the one hand, the mathematical language games of different forms of life and their family resemblances and, on the…

  1. Seeing Connections: Reason, Faith, and Education

    Science.gov (United States)

    Harris, Suzy

    2015-01-01

    The article explores some of the congruencies of thought and resonances in phrasing in the work of Janet Erskine Stuart, John Henry Newman and Ludwig Wittgenstein. These three writers have in common their resistance to philosophers of religion who are preoccupied with proposing arguments for the existence of God and grounds for believing in God.…

  2. The Crystal Order That Is Most Concrete: The Wittgenstein House

    Science.gov (United States)

    Zou, Hui

    2005-01-01

    This essay analyzes the bi-directional relationship between Ludwig Wittgenstein's philosophy and his architectural experiment of designing the Wittgenstein House. Putting the Wittgenstein House into the chronological context of Wittgenstein's philosophical writings, this research attempts to explore how his architectural design brought about a…

  3. Belief Systems and Language Understanding

    Science.gov (United States)

    1975-01-01

    Sedlak (1074), Searle (1060), Gtrawson (196U), and Wittgenstein (1958). [4] (1973), Charniak (1072), ilcCarthy and Hayes (1969), HcDermott (107...in Speech Acts", Philosophical Review 73, ^39-460. Wittgenstein , Ludwig 1958 Philosophical Investigations ( New York: The Macmillan Co.) (Tr

  4. Somaesthetics and Racism: Toward an Embodied Pedagogy of Difference

    Science.gov (United States)

    Granger, David A.

    2010-01-01

    This paper begins by examining the architectonics of the body and the mind-body relationship in the work of John Dewey, Michel Foucault, and Ludwig Wittgenstein. In doing so, it utilizes philosopher Richard Shusterman's analytic somaesthetics to expose the way racist ideology is covertly materialized and preserved through encoding in somatic norms…

  5. Identity, Language and Theology for the Proclamation of the Gospel

    Science.gov (United States)

    Goitia Padilla, Francisco Javier

    2012-01-01

    This dissertation is a linguistic approach to theology informed by the philosophical work of Ludwig Wittgenstein. It is situated in the construction of Puerto Rican identity in the elliptic Puerto Rican geography of the island and the Puerto Rican immigration settlements on the mainland. Its goal is the truthful proclamation of the Gospel to the…

  6. Somaesthetic Training, Aesthetics, Ethics, and the Politics of Difference in Richard Shusterman's "Body Consciousness"

    Science.gov (United States)

    Powell, Kimberly

    2010-01-01

    In this essay, the author first addresses the theme of disciplined somatic training and its relationship to self-awareness and transformation. Her attention is focused specifically on the chapter on Ludwig Wittgenstein, in which Richard Shusterman presents and then elaborates upon the philosopher's connections between conscious bodily feelings and…

  7. On Wittgenstein's Extension of the Domain of Aesthetic Education: Intransitive Knowledge and Ethics

    Science.gov (United States)

    Escalera, Carla Carmona

    2012-01-01

    Ludwig Wittgenstein gave priority to aesthetics over other disciplines due to its invaluable capacities for revealing certain aspects of the nature of human understanding and for guiding our actions toward an ethical life. Although Wittgenstein did not focus on these issues in a systematic way, these worries were present in his philosophy during…

  8. Imagining Wittgenstein's Adolescent: The Educational Significance of Expression

    Science.gov (United States)

    Frank, Jeff

    2012-01-01

    This paper highlights the philosophical and educational significance of expression in Ludwig Wittgenstein's Philosophical Investigations. When the role of expression is highlighted, we will be better able to appreciate Stanley Cavell's insistence that: (i) Wittgenstein offers ways of responding to, though not a refutation of, the problem of…

  9. The World of Instruction: Undertaking the Impossible

    Science.gov (United States)

    Laverty, Megan J.

    2014-01-01

    Throughout history, philosophers have reflected on educational questions. Some of their ideas emerged in defense of, or opposition to, skepticism about the possibility of formal teaching and learning. These philosophers include Plato, Augustine, St Thomas Aquinas, Søren Kierkegaard, Martin Heidegger, and Ludwig Wittgenstein. Together, they…

  10. Tænk ikke, men se efter! - Wittgensteins brug af eksemplet

    DEFF Research Database (Denmark)

    Krause-Jensen, Niels Henrik

    2016-01-01

    I dette kapitel er ærindet at præsentere en filosofisk metode, som på en langt mere gennemgribende måde end vanligt orienterer sig efter eksempler. Udgangspunktet er sprogfilosoffen Ludwig Wittgensteins tænkning, hvor det vises, at der er noget ganske særligt på spil: Eksempler bruges ikke til...

  11. "I Knew Jean-Paul Sartre": Philosophy of Education as Comedy

    Science.gov (United States)

    Griffiths, Morwenna; Peters, Michael A.

    2014-01-01

    Ludwig Wittgenstein suggests that "A serious and good philosophical work could be written consisting entirely of jokes". The idea for this dialogue comes from a conversation that Michael Peters and Morwenna Griffiths had at the Philosophy of Education of Great Britain annual meeting at the University of Oxford, 2011. It was sparked by an…

  12. Silence, an Eye of Knowledge

    Science.gov (United States)

    Aghamohammadi, Mehdi

    2017-01-01

    One of the conspicuous features of the twentieth-century West was silence. This idea could be supported by examining reflections of Ludwig Wittgenstein, Fritz Mauthner, John Cage, Samuel Beckett, Ihab Hassan, Franz Kafka, Wassily Kandinsky, Jean-Paul Sartre, Virginia Woolf, Wolfgang Iser, Jacques Derrida, and Pierre Macherey. To me, silence is not…

  13. H2O2 induces a transient multi-phase cell cycle arrest in mouse fibroblasts through modulating cyclin D and p21Cip1 expression

    NARCIS (Netherlands)

    Barnouin, K.; Dubuisson, M.L.; Child, E.S.; Fernandez de Mattos, S.; Glassford, J.; Medema, R.H.; Mann, D.J.; Lam, E.W.-F.

    2002-01-01

    From the h CRC Laboratories and the Section of Cancer Cell Biology, Imperial College School of Medicine at Hammersmith Hospital, Du Cane Road, London W12 ONN, United Kingdom, the e Ludwig Institute for Cancer Research and Section of Virology and Cell Biology, Imperial College School of Medicine at

  14. Stuart Hall on Racism and the Importance of Diasporic Thinking

    Science.gov (United States)

    Rizvi, Fazal

    2015-01-01

    In this article, I want to show how my initial encounter with the work of Stuart Hall was grounded in my reading of the later philosophy of Ludwig Wittgenstein, and was shaped by my interest in understanding the nature of racism across the three countries in which I had lived. Over the years, Hall's various writings have helped me to make sense of…

  15. “and africa will be saved!”? nadenke oor die kerk, die sending en die ...

    African Journals Online (AJOL)

    Livingstone (1813-1873) with his emphasis on “Christianity, civilisation, commerce” had high expectations that Western influence would lead to total new conditions in. Africa and the end of slave trade. Ludwig Krapf (1810-1881) was very sceptical con- cerning Western influence and of opinion that it would only lead to ...

  16. Empathy without borders? Cross-cultural heart and mind-reading in ...

    African Journals Online (AJOL)

    Background: This cross-cultural study was designed to examine cultural differences in empathy levels of first-year medical students. Methods: A total of 257 students from the academic year 2010/11, 131 at Jimma University, Ethiopia, and 126 at the Ludwig Maximilian University, Munich, Germany, completed the Balanced ...

  17. Fuldskalamodellen

    DEFF Research Database (Denmark)

    Søberg, Martin

    2017-01-01

    Fehn’s project for an extension of the Royal Danish Theatre (1996), Robbrecht en Daem architecten’s Mies 1:1. Das Golfklub Projekt (2013), the full-scale model of Ludwig Mies van der Rohe’s proposal for the Kröller-Müller villa (1912), Bungalow Germania – the German pavilion at the Venice Architecture...

  18. Semantic Elements in Deep Structures as Seen from a Modernist Definition of Clarity.

    Science.gov (United States)

    Lemke, Alan

    Typically, teachers approach ambiguity in student writing by suggesting that students focus on diction, syntax, and writing format; however, the works of modernists (including T.S. Eliot, Ludwig Wittgenstein, Karl Marx, and Pablo Picasso) suggest the importance of conceptions of semantic clarity. Transformational models for syntactic elements in…

  19. Electron transfer among the CuA-, heme b- and a3-centers of Thermus thermophilus cytochrome ba3

    DEFF Research Database (Denmark)

    Farver, Ole; Chen, Ying; Fee, James A

    2006-01-01

    The 1-methyl-nicotinamide radical (MNA(*)), produced by pulse radiolysis has previously been shown to reduce the Cu(A)-site of cytochromes aa(3), a process followed by intramolecular electron transfer (ET) to the heme a but not to the heme a(3) [Farver, O., Grell, E., Ludwig, B., Michel, H. and P...

  20. "Esialgses vormis, ilma olulisema inetamise ja muutmiseta" : Tallinna Oleviste kiriku taastamine pärast 1820. aasta tulekahju / Ants Hein

    Index Scriptorium Estoniae

    Hein, Ants, 1952-

    2015-01-01

    Tulekahjust. Taastamistööde finantseerimisest. Kahest olulisest nimest Oleviste ehitusloos - Alexander Feldmann'ist ja Friedrich Ludwig von Maydell'ist. Taastamistööde käigust. Altaritest ja kantslist. Tisleritöödest, orelist

  1. Mies kahes muuseumis korraga / Maria-Kristiina Soomre

    Index Scriptorium Estoniae

    Soomre, Maria-Kristiina, 1978-

    2001-01-01

    2001. a. suvel avab New Yorgi Museum of Modern Art arhitekt Ludwig Mies van der Rohe algusaastate tööle keskenduva näituse "Mies in Berlin" ja Whitney Museum of American Art arhitekti ameerika perioodi kajastava näituse "Mies in America".

  2. Pouť Ludwiga Protze z Kynšperku do Walhally a zase zpět aneb jak českoslovenští turneři chápali umění

    Czech Academy of Sciences Publication Activity Database

    Kessler, Vojtěch; Klement, M.

    2015-01-01

    Roč. 16, 1-2 (2015), s. 27-52 ISSN 1211-8109 Institutional support: RVO:67985963 Keywords : German Turner Association * Ludwig Protz * Kynšperk nad Ohří * Offenhausen * art * worldview Subject RIV: AB - History

  3. An ecotoxicological screening tool to prioritise acid mine drainage impacted streams for future restoration

    CSIR Research Space (South Africa)

    Oberholster, Paul

    2013-05-01

    Full Text Available review of laboratory studies. Water, 574 Air, & Soil Pollution 60, 135-148. 575 Ludwig J.A., Reynolds J.F., 1988. Statistical ecology. John Wiley and Sons, New York. 576 Margalef R., 1951. Diversidad de especies en las comunidades naturales...

  4. Political Communication with Animals

    NARCIS (Netherlands)

    Meijer, E.

    2013-01-01

    In this article I sketch the outlines of a theory of political human-animal conversations, based on ideas about language that I borrow from Ludwig Wittgenstein’s later work, in particular his notion of language-games. I present this theory as a supplement to the political theory of animal rights Sue

  5. Calculation of multigroup reaction rates for the Ghana Research ...

    African Journals Online (AJOL)

    The discrete ordinate spatial model, which pro-vides solution to the differential form of the transport equation by the Carlson-SN (N=4) approach was adopted to solve the Ludwig-Boltzmann multigroup neutron transport equation for this analysis. The results show that for any fissile resonance absorber, the reaction rates ...

  6. [A creator of modern surgery--Johann von Mikulicz-Radecki and contemporary ophthalmologists at the University of Wroclaw at the turn of the 19th-20th century].

    Science.gov (United States)

    Nizankowska, Maria Hanna; Kalinowska, Joanna; Pacan, Anna

    2005-01-01

    The authors present the history of the life and achievements of Jan Mikulicz-Radecki as the creator of modern surgery and his own school of surgery, especially during his work at the Wroclaw University in 1890-1905 years. The contemporary ophthalmologists as Richard Foerster, Hermann Ludwig Cohn, Wilhelm Uhthoff and theirs famous coworkers are also presented.

  7. The "Bologna-München" Tandem--Experiencing Interculturality

    Science.gov (United States)

    De Martino, Sandro

    2016-01-01

    This case study describes the "Bologna-München" Tandem, a cross-border collaboration which began in 2011. The aim of the collaboration is to give students studying Italian at the Ludwig- Maximilians-University in Munich and students studying German at the University of Bologna the opportunity to experience interculturality through…

  8. Ungari fotograafiast / Gregor Taul

    Index Scriptorium Estoniae

    Taul, Gregor, 1986-

    2010-01-01

    Näitus "Robert Capa" Ludwig Muzeumis Budapestis 3. juulist 11. oktoobrini 2009. Näitus "Traditsioon ja vastuvõtlikkus - kaasaegsed arengusuunad Ungari fotokunstis" ArtDepoo galeriis 2. septembrist 29. septembrini 2009. Fotograaf Robert Capa (Endre Ernö Friedmann, sünd. 1913) elust ja karjäärist

  9. The Coast Artillery Journal. Volume 70, Number 3, March 1929

    Science.gov (United States)

    1929-03-01

    Presidency receive but thirty-two pages. Surely Mr. Lincoln’s years in the White House were worth more than that. The typography is excellent, with an...Beuve; Frederick the Great, by T. B. Macaulay; Napoleon_’Bonaparte, by George Brandes ; and Otto von Bismarck, by Emil Ludwig. The book contains more

  10. Self-organization of vegetation in arid ecosystems

    NARCIS (Netherlands)

    Rietkerk, M.G.; Boerlijst, M.; Langevelde, F. van; HillerisLambers, R.; Koppel, J. van de; Kumar, L.; Prins, H.H.T.; Roos, A.M. de

    2002-01-01

    Scientists are still searching for possible unifying mechanisms to explain this range of spatial patterns (Tongway and Ludwig 2001), and an important question of this research is whether this range is the result of preexisting environmental heterogeneity, the result of spatial

  11. Maailma kaunid aiad : Nymans'i aed / Ann Tenno

    Index Scriptorium Estoniae

    Tenno, Ann, 1952-

    2004-01-01

    Nymans'i aia Inglismaal rajas 1885. a. Ludwig Messel ning kujundas seda koos oma poja Leonard Messeliga. Aed on tuntud haruldaste puude ja põõsaste rohkuse poolest, aia omapäraks on kerakujuliseks pöetud ja väljalõigatud siiludega jugapuud. 19 ill

  12. Distributional Monte Carlo Methods for the Boltzmann Equation

    Science.gov (United States)

    2013-03-01

    postulated by Ludwig Boltzmann [23] at a time when the atomic makeup of matter was not an accepted concept. Modern physics realizes Boltzmann’s vision...über Gastheorie 1898. Translated by S.G. Brush ., 1964. [24] Boyles, K.A., G.J. LeBeau, and M.A. Gallis. “DSMC Simulations in Support of the Columbia

  13. El cáncer en el cine: Un recurso para los profesionales de la salud Cancer in the movies: A resource for health professionals

    Directory of Open Access Journals (Sweden)

    M.T. Icart-Isern

    2009-12-01

    Full Text Available Objetivo: Describir las características de los pacientes y del proceso oncológico, a través de una muestra de películas disponibles en DVD. Materiales y métodos: Estudio descriptivo transversal. Se analizó una muestra de conveniencia de películas en las que el cáncer tenía carácter "puntual", "relevante" o "argumental". Cada película fue visionada por dos observadores que registraron variables del paciente (edad, sexo, estado civil, etc., del proceso oncológico (síntomas, pruebas diagnósticas, tratamientos y evolución y del entorno sanitario, entre otras. Resultados: Se analizaron 33 películas producidas en 11 países (1939-2008. El 58% de los pacientes eran varones; y el 47% pertenecía a las clases altas y media-alta. La localización más frecuente del cáncer fue en cerebro y en sangre, con seis casos para cada localización. La media de síntomas por título fue de 3,63; la clínica general (dolor, fatiga, anorexia, etc. se observó en el 43,32% de las películas. Las pruebas diagnósticas se mencionaron en el 85% de los títulos. El tratamiento más frecuente fue la analgesia y la quimioterapia; no obstante, fallecieron 19 pacientes (58%. Los médicos y las enfermeras intervinieron en 28 y 22 títulos, respectivamente. Conclusiones: El cáncer que muestra el cine difiere de la realidad: por cuanto el cine prefiere los pacientes jóvenes, de clase social alta y las localizaciones más fotogénicas. La clínica, las pruebas diagnósticas y los tratamientos suelen reflejar la realidad, sobre todo en las películas de las últimas décadas y en las que el cáncer tiene carácter "argumental"; algunos de cuyos títulos pueden ser un recurso de primer orden para la formación de los profesionales de la salud.Aim: To describe the characteristics of the patients and the cancer process, through a sample of films available in DVD. Materials and methods: Cross-sectional descriptive study. A sample of convenience of films was analyzed

  14. Androgenic alopecia in women: an Indian perspective.

    Science.gov (United States)

    Sehgal, Virendra N; Srivastava, Govind; Aggarwal, Ashok K; Midha, Reshmi

    2013-01-01

    The authors sought to investigate androgenic alopecia (AA) utilizing clinical and investigative procedures to establish the pattern of AA in the Indian subcontinent. A total of 35 consecutive women presenting with AA were included. After obtaining informed consent, a detailed history/examination, hair pull test, trichogram, and a scalp biopsy were performed in patients. AA classification was attempted across Ludwig and Norwood guidelines. Of 35 women, 16 had grade I, 10 had grade II, and 1 had grade III Ludwig classification. In addition, 6 other women had Christmas tree baldness: 1 each of fronto-parietal and male pattern baldness. Several investigations including hormonal profile were inconclusive; however, hair pull test and trichogram may be helpful in understanding the sequence in AA in women. AA has infrequently been reported, particularly India and in Asia in general.

  15. Editor's note: Reviews in Modern Astronomy 27

    Science.gov (United States)

    Berlepsch, Regina v.

    2015-06-01

    In order to make the scientific events of the meetings of the Astronomische Gese llschaft (AG) more international and bring them to the attention of the worldwide astronomical community, it was decided to devote the Reviews in Modern Astronomy} to the outcomes of the large annual fall meetings of the AG. In particular, it emphasized the Karl Schwarzschild Lectures, the Ludwig Biermann Award Lectures, the invited reviews, and the highlight contributions on recent progress and achievements from leading scientists. The most prestigious of them, the Karl Schwarzschild Lectures, constitutes a special series of reviews by outstanding scientists who have been awarded the Karl Schwarzschild Medal during the fall meeting of the AG. At the same time, excellent young astronomers are honored by the Ludwig Biermann Award. In 2010 the ``Doctoral Thesis Award'' was established to honor the most outstanding Doctoral Thesis of the past year.

  16. National Calendar-2009

    Science.gov (United States)

    Ghedrovici, Vera; Svet, Maria; Matvei, Valeria; Perju, Elena; Sargun, Maria; Netida, Maria

    2009-10-01

    The calendar represents a few hundreds of biographies of scientists, artists and writers from everywhere, printed in chronological order and adjusted to their birthdays. A number of international and national holydays, including some refering to science are included in the Calendar. A great deffect of the Calendar is the introduction in the list of holydays of the "international day of astrology". Another defect is the absence of the indication of the membership to Communist Parties for persons cited from the former USSR and former Communist Countries. The following physicists, astronomers and mathematicians had biographies in the actual issue: Kon, Lia Z., Arnautov, Vladimir I. (math), Tsukerblat, B., Kapitza, P., Donici (Donitch), N.N., Sklodowska-Curie, Maria, da Vinci, Leonardo, Birkhof, George David, Galilei, Galileo, Pisarzhveskij, Lev (chemist), Mossbauer, Rudolf Ludwig, Clochisner (Klokishner), Sofia I., Miscoi (Mishkoy), Gh. (Math), Mendel, Gregor Lohan (genet.), Glavan, Vasile (math), Chetrus (Ketrush), P. (chem), Bostan, Ion (mech. eng.), Boltzmann, Ludwig Ed.

  17. JPRS Report Science & Technology Japan

    Science.gov (United States)

    1989-10-25

    Ernaehrungsphysiologie Max-Planck-Institut fuer Biochemie Institut fuer Biochemie, Ludwig-Maximilian-Universitaet Instituto di Chimica, Facolt’ di Medicina ...issue to be discussed from the administrative and legal perspectives] (1) Board of Directors This is a board whose members are scientists. The...envisaged; 3. The participants urge that the time is now ripe for the governments of the countries involved to discuss an appropriate legal

  18. Wittgenstein, medicine and neuropsychiatry

    Directory of Open Access Journals (Sweden)

    Hélio A.G. Teive

    2011-08-01

    Full Text Available A historical review is presented of the link between Ludwig Wittgenstein, considered the most important philosopher of the 20th century, and medicine, particularly neurology and psychiatry. Wittgenstein worked as a porter at Guy's Hospital in London, and then as a technician at the Royal Victoria Infirmary in Newcastle. He wrote about his important insights into language, and neuroscience. It has been suggested that he had Asperger syndrome and a possible movement disorder (mannerisms.

  19. Nuclear medical approaches to clinical research; Nuklearmedizinische Ansaetze in der klinischen Forschung

    Energy Technology Data Exchange (ETDEWEB)

    Otte, Andreas; Nguyen, Tristan (eds.)

    2009-11-15

    In the frame of the master course Clinical research management at the scientific college Lahr in cooperation with the Albert-Ludwigs-University Freiburg three contributions are presented: Functional imaging - supported clinical studies in the sleep research. A comparison of NMR imaging versus SPECT and PET (advantages and disadvantages). Clinical studies with ionizing radiation and the radiation fear of the public. The new radioimmunotherapeutic agent Zevalin and the challenges at the market.

  20. Nuclear medical approaches to clinical research

    International Nuclear Information System (INIS)

    Otte, Andreas; Nguyen, Tristan

    2009-01-01

    In the frame of the master course Clinical research management at the scientific college Lahr in cooperation with the Albert-Ludwigs-University Freiburg three contributions are presented: Functional imaging - supported clinical studies in the sleep research. A comparison of NMR imaging versus SPECT and PET (advantages and disadvantages). Clinical studies with ionizing radiation and the radiation fear of the public. The new radioimmunotherapeutic agent Zevalin and the challenges at the market.

  1. Three Hungarian researchers and three periods of the history and culture of the Albanian people

    OpenAIRE

    Myrvete Dreshaj-Baliu

    2016-01-01

    The object of this study is the contribution of three Hungarian researchers: the publicist, the editor and the historian Windisch (Karl Go$ lieb von Windisch, 1725 -1793); the outstanding historian, medievalist, latinist and germanist Thalloczy (Ludwig von Thallóczy, 1857-1916); and the geographer and ethnographer of international dimensions Nopcsa (Baron Nopcsha 1877-1933). Their selection is not random; it refl ects the up to now development in the science of Albanology and our goal as rese...

  2. Leadership in the Shenandoah Valley and North Africa: Historical Studies in Mission Command

    Science.gov (United States)

    2013-06-13

    had even less to go back to, in Jackson’s Mill.66 Although his classmates found him socially reserved and eccentric , he earned their respect...transferred to Jackson’s command. Although it would take time for them to arrive, the wheels were in motion to build a force capable of operating against...under General Ludwig Cruewell, Commander of the Afrika Korps, would act as a fixing force and conduct a feint while the southern wing wheeled and

  3. Prevalence and natural history of ALK positive non-small-cell lung cancer and the clinical impact of targeted therapy with ALK inhibitors

    OpenAIRE

    Chia, Puey Ling; John,Thomas; Dobrovic,Alex; Mitchell,Paul

    2014-01-01

    Puey Ling Chia,1 Paul Mitchell,1 Alexander Dobrovic,2–4 Thomas John1,2,4 1Department of Medical Oncology, Olivia-Newton John Cancer and Wellness Centre, Victoria, Australia; 2Ludwig Institute for Cancer Research, Austin Health, Victoria, Australia; 3Department of Pathology, University of Melbourne, Victoria, Australia; 4School of Cancer Medicine, La Trobe University, Victoria, Australia Abstract: Improved understanding of molecular drivers of carcinogenesis has led to significant p...

  4. The uncertainty principle

    International Nuclear Information System (INIS)

    Martens, Hans.

    1991-01-01

    The subject of this thesis is the uncertainty principle (UP). The UP is one of the most characteristic points of differences between quantum and classical mechanics. The starting point of this thesis is the work of Niels Bohr. Besides the discussion the work is also analyzed. For the discussion of the different aspects of the UP the formalism of Davies and Ludwig is used instead of the more commonly used formalism of Neumann and Dirac. (author). 214 refs.; 23 figs

  5. Limpsides arhitektuuri = Licking Architecture / Thibaut de Ruyter

    Index Scriptorium Estoniae

    Ruyter, Thibaut de

    2006-01-01

    Autor kritiseerib kaasaegset meedia- ja pildikeskset maailma, kus arhitektuuriväljaannete rohkuses on kaduma läinud külastaja ja ehitise vahetu kogemuslik suhe. 1980-ndatel uuesti üles ehitatud Barcelona Paviljonist (Ludwig Mies van der Rohe), Hollandi saatkonna hoonest Berliinis (Rem Koolhaas), Andrea Fraseri (1965) Bilbao Guggenheimi muuseumis (Frank O. Gehry) 2001. a. tehtud videost "Little Frank and His Carp"

  6. Idrottsutövandets estetik : en narrativ studie om meningsskapande och lärande

    OpenAIRE

    Maivorsdotter, Ninitha

    2012-01-01

    The overall interest of this thesis is to explore aesthetic experience in sport and its significance for learning in sport. The main purpose is to contribute to a theoretical and methodological development of studies relating to learning in sport. The exploration is undertaken within the field of pragmatism using the works of John Dewey and Ludwig Wittgenstein. The exploration consists of four case studies, consisting mainly of narrative analyses of people’s written stories of participating i...

  7. EXECUTIVE COMMITTEE

    CERN Multimedia

    Association du personnel

    2010-01-01

    Composition 2010 Président :  Gianni DEROMA Vice-président :  Marcel AYMON Vice-président :  Sébastien EVRARD Secrétaire :  Michel GOOSSENS Trésorier :  Céline GROBON Membres :  Philippe DEFFERT  Roger GIRARDOT  Serge GRILLOT  Catherine LAVERRIERE  Michael LUDWIG  Sonia MALLON AMERIGO  Isabelle MARDIROSSIAN

  8. An Analysis of the Observed Low-level Structure of Rapidly Intensifying and Mature Hurricane Earl (2010)

    Science.gov (United States)

    2014-01-01

    structure. J. Atmos. Sci. 49: 919–942. Marks FD, Black PG, Montgomery MT, Burpee RW. 2008. Structure of the eye and eyewall of hurricane Hugo (1989...structure of rapidly intensifying and mature hurricane Earl (2010) Michael T. Montgomery,a* Jun A. Zhangb and Roger K. Smithc aDepartment of Meteorology...Naval Postgraduate School, Monterey, CA, USA bNOAA Hurricane Research Division, Miami, FL, USA cMeteorological Institute, Ludwig Maximilians, University

  9. Kõnelused Tartus / Anne Untera

    Index Scriptorium Estoniae

    Untera, Anne, 1951-

    2007-01-01

    8.-10. V Tartus toimunud eesti, läti ja saksa kunstiteadlaste ühisseminarist. Alexander Knorre rääkis Karl August Senffi, Ilona Audere Friedrich Ludwig von Maydelli, Mai Levin Karl Alexander von Winkleri, Kristiana Abele Johann Walter-Kurau (1869-1932), Anne Untera Konstantin ja Sally von Kügelgeni, Epp Preem Julie Hagen-Schwartzi, Friedrich Gross Eduard von Gebhardti ja Katharina Hadding Ida Kerkoviuse (1879-1970) loomingust

  10. Krimiens filosofiske undersøgelser

    DEFF Research Database (Denmark)

    Hansen, Kim Toft

    I denne artikel tager Kim Toft Hansen over tre trin fat på Henning Mortensens forfatterskab og primært dennes såkaldte Sondrup-trilogi. Første trin bliver at præcisere, hvordan Mortensen metafiktivt dekonstruerer krimiens form. Andet trin analyserer Mortensens samfundskritik, der dukker op trods ...... dekonstruerende elementer. Tredje og sidste trin fokuserer på de filosofiske implikationer i Mortensens eksplicitte brug af Ludwig Wittgensteins filosofi....

  11. Object-oriented simulator of the dynamics of Embalse nuclear power plant

    International Nuclear Information System (INIS)

    Boroni, Gustavo A.; Cuadrado, M.; Clausse, Alejandro

    2000-01-01

    LUDWIG is an object-oriented simulator of the dynamics of the CANDU Nuclear power plant Embalse Rio Tercero. The tool consists in a numerical plant analyzer by means of a model of the plant dynamics during normal operation, and a graphic environment for configuration and visualization of results. The simulator was validated against plant transients occurred in the plant and recorded in the past. (author)

  12. A parameterization for the absorption of solar radiation by water vapor in the earth's atmosphere

    Science.gov (United States)

    Wang, W.-C.

    1976-01-01

    A parameterization for the absorption of solar radiation as a function of the amount of water vapor in the earth's atmosphere is obtained. Absorption computations are based on the Goody band model and the near-infrared absorption band data of Ludwig et al. A two-parameter Curtis-Godson approximation is used to treat the inhomogeneous atmosphere. Heating rates based on a frequently used one-parameter pressure-scaling approximation are also discussed and compared with the present parameterization.

  13. Mere Libertarianism: Blending Hayek and Rothbard

    OpenAIRE

    Klein, Daniel

    2003-01-01

    As many have argued, libertarianism as idea and movement contains strands that often conflict, beg questions, or try our sensibilities. There are multiple libertarianisms. Two leading theorists of modern libertarianism are Friedrich Hayek and Murray Rothbard. Both pupils of Ludwig von Mises, Hayek and Rothbard provide dual libertarianisms that share a common precept but sustain that precept in inverse ways. Both Hayek and Rothbard maintain that, in societies like theirs, the desirable always ...

  14. Analytic index of Wittgenstein´s Nachlass

    DEFF Research Database (Denmark)

    2010-01-01

    Together with Professor Mark Addis Birmingham and the Research Team at AKSIS, Bergen University, I have developed an interactive analytic index to the whole of the Nachlass of LudwigWittgenstein. The project is funded by Nordforsk/WAB-Bergen/VWA-Helsinki , and is associated with the EU discovery ...... program, and the European Cultural Heritage program. The application is available on the web at the Philospace Home Page....

  15. The Effect of Diethylene Glycol Monomethyl Ether (DiEGME) on Microbial Contamination of Jet Fuel: A Minimum Concentration Study

    Science.gov (United States)

    2010-03-01

    Prescott , L. M.; Harley, J. P.; Klein, D. A. Microbiology . Fifth edition. McGraw Hill: New York, 2002. 26. Amman, R. I., Ludwig, W., Schleifer, K. H...Recent advances in petroleum microbiology . Microbiology and molecular biology reviews 2003, 67, 503-49. 6. Langer, G. JP-4 Fuel System Icing. Armour...Wright Air Development Center. 8. Elderfield, R. C. Proceedings on Jet Fuel Microbiology and Corrosion Conference. Prevention of Deterioration Center

  16. The Logical Basis of Evaluation Order and Pattern-Matching

    Science.gov (United States)

    2009-04-17

    various people in the 1930s, particularly Wittgenstein (“It is what is regarded as the justification of an assertion that constitutes the sense of the...assertion” [ Wittgenstein , 1974, I,§40]), and Brouwer-Heyting-Kolmogorov in their interpretations of intuitionistic logic [Heyting, 1974, Kolmogorov, 1932...Technical Report CMU-CS-02-101, Department of Computer Science, Carnegie Mellon University, 2002. Revised May 2003. Ludwig Wittgenstein

  17. Wittgenstein, medicine and neuropsychiatry.

    Science.gov (United States)

    Teive, Hélio A G; Silva, Guilherme Ghizoni; Munhoz, Renato P

    2011-08-01

    A historical review is presented of the link between Ludwig Wittgenstein, considered the most important philosopher of the 20th century, and medicine, particularly neurology and psychiatry. Wittgenstein worked as a porter at Guy's Hospital in London, and then as a technician at the Royal Victoria Infirmary in Newcastle. He wrote about his important insights into language, and neuroscience. It has been suggested that he had Asperger syndrome and a possible movement disorder (mannerisms).

  18. Thomas Kuhn e a nova historiografia da ciência

    Directory of Open Access Journals (Sweden)

    Bernardo Jefferson de Oliveira

    2002-01-01

    Full Text Available This article tries to show the Thomas Kuhn's critics to some conceptions of the contemporary historiography of science that became radical many of the positions formulated initially by Kuhn himself. It is still intended to show that the new orientation of Kuhn, starting from his critic to his successors, approaches him more of his initial influences, especially, Ludwig Wittgenstein and Ludwik Fleck.

  19. Conditions for Confirmatory Analysis and Causal Inference.

    Science.gov (United States)

    1982-05-03

    such behavior evolved because it had survival value. Other philosophers have not been so kind in dealing with Hume’s skepticism. Wittgenstein regarded...also in many other ways." _ Ludwig Wittgenstein (1980) We begin this section by restating the third principle for the logical foundation of...study in Wittgenstein . Oxford: Basil Blackwell, 1973. Dubin, R. Theory building in applied areas. In M. D. Dunnette (Ed.), Handbook of industrial and

  20. Special Course on Subsonic/Transonic Aerodynamic Interference for Aircraft

    Science.gov (United States)

    1983-07-01

    memory requirements. Small disturbance methods are inadequate, and they offer no reduction in computer costs. 4-5 3.2 BOUNDARY LAYER METHODS Widely...20th Ludwig Prandtl Memorial Lecture 1141 in 1977. A study of the flow in a right angled streanraise corner with fully turbulent boundary layers...manoctivrant, ofi line orientation variable die jet propulsif perinet die faire participer le nioteur A la sustentation die I’avion (et gaknient 5 qon

  1. Putting to Rest WISHE-ful Misconceptions for Tropical Cyclone Intensification

    Science.gov (United States)

    2014-11-27

    Persing1, and Roger K. Smith2 1Department of Meteorology, Naval Postgraduate School , Monterey, California, USA, 2Meteorological Institute, Ludwig...NUMBER 5f. WORK UNIT NUMBER 7. PERFORMING ORGANIZATION NAME(S) AND ADDRESS(ES) Naval Postgraduate School ,Department of Meteorology,Monterey,CA,93943...paper presented at 29th Conference on Hurri- canes and Tropical Meteorology, p. 8C.7, Amer. Meteorol. Soc., Tucson, Ariz. Figure 7. Azimuthally-averaged

  2. Con Drury: philosopher and psychiatrist.

    Science.gov (United States)

    Hayes, John

    2017-12-01

    Maurice O'Connor Drury (1907-76), an Irish psychiatrist, is best known for his accounts of his close friendship with the eminent twentieth-century philosopher, Ludwig Wittgenstein. His only book, The Danger of Words (1973), was well received by those who had an interest in the relationship between psychiatry, psychology and philosophy. This article concentrates on Drury's experiences, studies and writings in these fields.

  3. Predictability of the individual clinical outcome of extracorporeal shock wave therapy for cellulite

    OpenAIRE

    Schlaudraff, Kai-Uwe; Kiessling, Maren C; Császár, Nikolaus BM; Schmitz, Christoph

    2014-01-01

    Kai-Uwe Schlaudraff,1 Maren C Kiessling,2 Nikolaus BM Császár,2 Christoph Schmitz21Concept Clinic, Geneva, Switzerland; 2Department of Anatomy II, Ludwig-Maximilians-University of Munich, Munich, GermanyBackground: Extracorporeal shock wave therapy has been successfully introduced for the treatment of cellulite in recent years. However, it is still unknown whether the individual clinical outcome of cellulite treatment with extracorporeal shock wave therapy can be predict...

  4. Paul Ehrenfest

    International Nuclear Information System (INIS)

    Broda, E.

    1982-01-01

    This is a short biography about Paul Ehrenfest, a famous austrian physicist and student of Ludwig Boltzmann. Ehrenfest contributed important work to thermodynamics and quantum mechanics (a.o. adiabatic invariants, and the Ehrenfest theorem). Broda describes not only his scientific research but also his interaction and relation to other famous physicist of his time, like Erwin Schrödinger, Albert Einstein and others. (nowak)

  5. Ecology of Postlarval Stages of Chigger Mites.

    Science.gov (United States)

    1985-12-05

    annual meeting of Georgia Entomological Society, Tifton GA . Hayes, M. J., D. A. Crossley, Jr. and D. F. Ludwig. 1883. The behaviorial response of larval...A. Crossley, Jr. Ph.D., Principal Investigator Research Professor, Department of Entomology University of Georgia, Athens, GA . 30602 ?~f. and #.i...Mary Jo Hayes, Ph.D. Post-doctoral Associate, Department of Entomology University of Georgia, Athens, GA . 30602 Approved for public release

  6. Kayh am Beginn der Neuzeit

    OpenAIRE

    Trugenberger, Volker

    1990-01-01

    Die Kayher Gegend barg in ihrem Boden einen besonderen Schatz: Alabaster. Herzog Ludwig von Württemberg kaufte eigens zwischen 1581 und 1586 von den Kayher Bürgern Urban Binder, Jakob Schwarz und Martin Noppel deren auf Altinger Markung uffm kreidengraben gelegene Äcker mit alapasterstein, insgesamt 2 Morgen. Der darauf gebrochene Alabaster wurde für Kunstwerke verwandt, die im Auftrag des Herzogs angefertigt wurden; er wurde nicht abgebaut, um ihn anderweitig zu verkaufen und damit Gewinne z...

  7. 'GORGEOUS MONSTROSITY': DERRIDA'S DECONSTRUCTION AS AN ALTERNATIVE POSTMODERNIST TOOL IN ANALYSING ALASDAIR GRAY'S POOR THINGS

    OpenAIRE

    Joanna Małecka

    2009-01-01

    The article is a postmodernism interpretation of Alasdair Gray's acclaimed novel "The Poor Things". The main motifs in the novel are re-read in the light of the theories of Jacques Derrida and Ludwig Wittgenstein. At the centre of the analysis stands the intertextual and deconstructive reading of the role of the main heroine, Bella Baxter. As the novel's 'gorgeous monstrosity', Bella is a prototype construct embedded in the linguistic nature of reality. In Gray's postmodern vision, Bella embo...

  8. Landscape fragmentation in South Coast Renosterveld, South Africa, in relation to rainfall and topography

    CSIR Research Space (South Africa)

    Kemper, J

    2000-04-01

    Full Text Available be identified on the basis of irreplaceability (presence of unique attributes; contribution to achiev- ing a reservation goal) and on actual and potential threats (Pressey et al. 1996). ACKNOWLEDGEMENTS We thank William Bond, Steven Higgins, Richard Hobbs, John... Ludwig and Chris Margules for com- menting on earlier versions of this manuscript. CSIR, South Africa and the Pew Charitable Trust are thanked for funding this project. REFERENCES Computer Centre for Water Research (1996) Computer Centre for Water...

  9. TiO2 micro-nano-hybrid surface to alleviate biological aging of UV-photofunctionalized titanium

    OpenAIRE

    Iwasa F; Tsukimura N; Sugita Y, Kanuru RK; Kubo K; Hasnain H; Att W; Ogawa T

    2011-01-01

    Fuminori Iwasa1, Naoki Tsukimura1, Yoshihiko Sugita1, Rajita Kodali Kanuru1, Katsutoshi Kubo1, Hafiz Hasnain1, Wael Att1,2, Takahiro Ogawa11Laboratory of Bone and Implant Sciences (LBIS), The Weintraub Center for Reconstructive Biotechnology, Division of Advanced Prosthodontics, Biomaterials and Hospital Dentistry, UCLA School of Dentistry, Los Angeles, CA, USA; 2Department of Prosthodontics, Dental School, Albert-Ludwigs University, Freiburg, GermanyAbstract: Bioactivity and osteoconductivit...

  10. Teaching physics in a physiologically meaningful manner

    OpenAIRE

    Michael Plomer; Karsten Jessen; Georgi Rangelov; Michael Meyer

    2010-01-01

    The learning outcome of a physics laboratory course for medical students was examined in an interdisciplinary field study and discussed for the electrical physiology (“Propagation of Excitation and Nerve Cells”). At the Ludwig-Maximilians-University of Munich (LMU) at a time about 300 medicine students were assessed in two successive years. Students from the control group worked with standard experiments, while students from the treatment group performed newly developed “addressee-specific” e...

  11. Pynchon and Wittgenstein: ethics, relativism and philosophical methodology

    OpenAIRE

    Eve, Martin Paul

    2014-01-01

    This piece presents a tripartite analysis of the relationship between the philosophical works of Ludwig Wittgenstein and the novels of Thomas Pynchon. This is broadly structured around three schools of Wittgenstein scholarship identified by Guy Kahane et al. as the Orthodox Tractatus, the New Wittgenstein, and several strands of the Orthodox Investigations (Kahane et al. 4-14). Moving from the earliest affiliation that Pynchon stages between Wittgenstein and Weissman, the underlying theme lie...

  12. Sobre o transcendental prático e a dialética da sociabilidade

    Directory of Open Access Journals (Sweden)

    Luiz Henrique Lopes dos Santos

    2011-07-01

    Full Text Available Ao escrever Apresentação do mundo: considerações sobre o pensamento de Ludwig Wittgenstein, as intenções de José Arthur Giannotti não eram principalmente exegéticas. Ele pretendia trilhar alguns caminhos abertos por Ludwig Wittgenstein no intuito de lidar com suas próprias obsessões filosóficas. Neste artigo, mostro por que e como algumas das linhas de pensamento de Wittgenstein ajudaram Giannotti a clarear logicamente alguns de seus próprios temas filosóficos obsessivos: o transcendental prático e a dialética da sociabilidade.In writing Presentation of the World: considerations on the thought of Ludwig Wittgenstein, Giannotti's intentions were not primarily exegetical. He aimed to follow some of Wittgenstein's conceptual pathways in order to deal with his own philosophical obsessions. In this paper, I show why and how some of Wittgenstein's lines of thought helped Giannotti to logically clarify a couple of his own obsessive philosophical themes: the practical transcendental and the dialectic of sociability.

  13. International perspectives on mitigating laboratory biorisks.

    Energy Technology Data Exchange (ETDEWEB)

    Pinard, William J.; Salazar, Carlos A.

    2010-11-01

    The International Perspectives on Mitigating Laboratory Biorisks workshop, held at the Renaissance Polat Istanbul Hotel in Istanbul, Republic of Turkey, from October 25 to 27, 2010, sought to promote discussion between experts and stakeholders from around the world on issues related to the management of biological risk in laboratories. The event was organized by Sandia National Laboratories International Biological Threat Reduction program, on behalf of the US Department of State Biosecurity Engagement Program and the US Department of Defense Cooperative Biological Engagement Program. The workshop came about as a response to US Under Secretary of State Ellen O. Tauscher's statements in Geneva on December 9, 2009, during the Annual Meeting of the States Parties to the Biological Weapons Convention (BWC). Pursuant to those remarks, the workshop was intended to provide a forum for interested countries to share information on biorisk management training, standards, and needs. Over the course of the meeting's three days, participants discussed diverse topics such as the role of risk assessment in laboratory biorisk management, strategies for mitigating risk, measurement of performance and upkeep, international standards, training and building workforce competence, and the important role of government and regulation. The meeting concluded with affirmations of the utility of international cooperation in this sphere and recognition of positive prospects for the future. The workshop was organized as a series of short presentations by international experts on the field of biorisk management, followed by breakout sessions in which participants were divided into four groups and urged to discuss a particular topic with the aid of a facilitator and a set of guiding questions. Rapporteurs were present during the plenary session as well as breakout sessions and in particular were tasked with taking notes during discussions and reporting back to the assembled participants

  14. El cáncer en el cine: Un recurso para los profesionales de la salud

    Directory of Open Access Journals (Sweden)

    M.T. Icart-Isern

    Full Text Available Objetivo: Describir las características de los pacientes y del proceso oncológico, a través de una muestra de películas disponibles en DVD. Materiales y métodos: Estudio descriptivo transversal. Se analizó una muestra de conveniencia de películas en las que el cáncer tenía carácter "puntual", "relevante" o "argumental". Cada película fue visionada por dos observadores que registraron variables del paciente (edad, sexo, estado civil, etc., del proceso oncológico (síntomas, pruebas diagnósticas, tratamientos y evolución y del entorno sanitario, entre otras. Resultados: Se analizaron 33 películas producidas en 11 países (1939-2008. El 58% de los pacientes eran varones; y el 47% pertenecía a las clases altas y media-alta. La localización más frecuente del cáncer fue en cerebro y en sangre, con seis casos para cada localización. La media de síntomas por título fue de 3,63; la clínica general (dolor, fatiga, anorexia, etc. se observó en el 43,32% de las películas. Las pruebas diagnósticas se mencionaron en el 85% de los títulos. El tratamiento más frecuente fue la analgesia y la quimioterapia; no obstante, fallecieron 19 pacientes (58%. Los médicos y las enfermeras intervinieron en 28 y 22 títulos, respectivamente. Conclusiones: El cáncer que muestra el cine difiere de la realidad: por cuanto el cine prefiere los pacientes jóvenes, de clase social alta y las localizaciones más fotogénicas. La clínica, las pruebas diagnósticas y los tratamientos suelen reflejar la realidad, sobre todo en las películas de las últimas décadas y en las que el cáncer tiene carácter "argumental"; algunos de cuyos títulos pueden ser un recurso de primer orden para la formación de los profesionales de la salud.

  15. Nel bosco sacro. Realtà, finzione, magia e natura ne Il ramo d’oro di James G. Frazer

    OpenAIRE

    Dimpflmeier, Fabiana

    2014-01-01

    ‘E così il coro accenna a una legge segreta’ : così vien voglia di commentare la raccolta dei dati in Frazer.(Ludwig Wittgenstein, Note sul Ramo d’oro di Fraser)Per certi versi, è di simili ‘infedeltà creative’ che si nutre il progresso della conoscenza.(Fabio Dei, La discesa agli inferi) Nel 1922, dopo tre edizioni arrivate ad espandersi fino a dodici volumi, l’antropologo vittoriano James G. Frazer pubblica l’editio minor de Il ramo d’oro, consacrandosi a fortuna quasi imperitura. Contraria...

  16. The design and implementation of multiplayer, web-based, 2D game made in client-server architecture

    OpenAIRE

    Chojnacki, Piotr; Duczmańska, Justyna

    2014-01-01

    Even though Ludwig Wittgenstein – Austrian-British philosopher – was the first man to address a definition of word “game”1 in his Philosophical Investigations book in 1953, games were known to human since the ancient times2. Because people are social beings and they long to interact with each other, a purpose of majority of games was – and still is – to spend time with others in a friendly atmosphere. It is also in human nature to face challenges and compete with other people and it is reflec...

  17. Hair biology and its comprehensive sequence in female pattern baldness: diagnosis and treatment modalities--Part I.

    Science.gov (United States)

    Sehgal, Virendra N; Srivastava, Govind; Aggarwal, Ashok K; Midha, Rashmi

    2013-01-01

    Hair may be a source of concern for patients when there is a change in its texture, amount, or thickness. It can present in women as androgenic alopecia also called female pattern baldness, and in men as adrogenic alopecia, also called male pattern baldness. Thinning/rarefaction affecting the vertex is a progressive condition, and hair loss in women has been interpreted and classified differently from that in men. The Ludwig classification for women's hair loss seems to be the most accepted assessment, which will be outlined in this review, along with the hair growth cycle that encompasses anagen, catagen, telogen, exogen, and kenogen.

  18. Institutions as Knowledge Capital

    DEFF Research Database (Denmark)

    Foss, Nicolai Juul; Garzarelli, Giampaolo

    The paper revisits the socioeconomic theory of the Austrian School economist Ludwig M. Lachmann. By showing that the common claim that Lachmann's idiosyncratic (read: eclectic and multidisciplinary) approach to economics entails nihilism is unfounded, it reaches the following conclusions. (1......) Lachmann held a sophisticated institutional position to economics that anticipated developments in contemporary new institutional economics. (2) Lachmann's sociological and economic reading of institutions offers insights for the problem of coordination. (3) Lachmann extends contemporary new institutional...... theory without simultaneously denying the policy approach of comparative institutional analysis. (90 words.)KeywordsComparative institutional analysis, coordination, expectations, institutionalevolution, interpretative institutionalism.JEL CodesB31, B52, B53, D80....

  19. Study of the water-rock interactions of spring waters in the Northern Apennines

    International Nuclear Information System (INIS)

    Venturelli, G.; Toscani, L.

    2000-01-01

    Forty three spring waters have been investigated in the Apennine area of Reggio Emilia province (Parco Regionale del Gigante, Italy). On the basis of the Langelier-Ludwig diagram, the (Na+K+Cl) vs (Ca+Mg) plot and the Cl content, the waters have been divided in five main groups. The chemical composition of the waters suggests that calcite is practically the only source of Ca and alkalinity for group D and E reflect ion exchange and calcite and minor silicate dissolution during a strong water-rock interaction at depth [it

  20. What is the Point? Ethics, Truth and the Tractatus

    DEFF Research Database (Denmark)

    Christensen, Anne-Marie Søndergaard

    2007-01-01

      In this paper, my major concern is to place the ethical remarks of Ludwig Wittgenstein's Tractatus within a wider discussion in moral philosophy. In the first part of the paper, I sketch a reading of the Tractatus that brings out a particular feature of ethics, namely the fact that ethical...... discourse is shaped by both subjective and objective concerns. Moving on, I unfold the subjective side of ethics by drawing on Stanley Cavell's notion of the point of an utterance, while the objective side will be presented via Diamond's writing on the importance of truth in ethics. My goal is to argue...

  1. Commercial trading of IaaS cloud resources

    CERN Multimedia

    CERN. Geneva; Dr. Watzl, Johannes

    2014-01-01

    Dr. Johannes Watzl is responsible for the Product Management at Deutsche Börse Cloud Exchange. His work is focused on the specification and introduction of new tradable products and and product features. Prior to his role at Deutsche Börse Cloud Exchange, Johannes was a researcher at Ludwig-Maximilians-Universität München where he worked at European Commission funded projects in the field of distributed computing and standardisation in grid and cloud computing and obtained his PhD. He started research on the...

  2. Irreversible processes kinetic theory

    CERN Document Server

    Brush, Stephen G

    2013-01-01

    Kinetic Theory, Volume 2: Irreversible Processes deals with the kinetic theory of gases and the irreversible processes they undergo. It includes the two papers by James Clerk Maxwell and Ludwig Boltzmann in which the basic equations for transport processes in gases are formulated, together with the first derivation of Boltzmann's ""H-theorem"" and a discussion of this theorem, along with the problem of irreversibility.Comprised of 10 chapters, this volume begins with an introduction to the fundamental nature of heat and of gases, along with Boltzmann's work on the kinetic theory of gases and s

  3. Validation of the prognostic value of histologic scoring systems in primary sclerosing cholangitis

    DEFF Research Database (Denmark)

    de Vries, Elisabeth M G; de Krijger, Manon; Färkkilä, Martti

    2017-01-01

    across a multicenter PSC cohort. Liver biopsies from PSC patients were collected from seven European institutions. Histologic scoring was performed using the Nakanuma, Ishak, and Ludwig scoring systems. Biopsies were independently scored by six liver pathologists for interobserver agreement.......19-5.80] for endpoint 2 and HR, 2.06 [95% CI, 1.09-3.89] for endpoint 3). Only the Nakanuma staging system was independently associated with endpoint 1: HR, 2.14 (95% CI, 1.22-3.77). Interobserver agreement was moderate for Nakanuma stage (κ = 0.56) and substantial for Nakanuma component fibrosis (κ = 0.67), Ishak...

  4. [Jesuits Chemists of Hapsburg Monarchy].

    Science.gov (United States)

    Južnič, Stanislav

    2016-01-01

    The achievements of the Jesuits from the Austrian and Bohemian provinces, who have published books on chemistry are focused. Their links with the area of today's Slovenia are particularly exposed. The guidelines which have enabled prompt victories of the ideas about the structure of matter of Jesuit Ru|er Bokovi are indicated. Inconceivable fast spread of Bošković's adherents in the Hapsburg monarchy is compared with a similar rapid introduction of the kinetic theories of atoms of Slovene Jožef Stefan and Ludwig Boltzmann in the same geographical area. Boltzmann was not only Stefan's best student, but he also married a half Slovenian maid.

  5. Verhandeln in Briefen. Frauen in der höfischen Diplomatie des frühen 18. Jahrhunderts von Corina Bastian

    Directory of Open Access Journals (Sweden)

    Paul Winkler

    2014-09-01

    Full Text Available Corina Bastian wertet innerhalb ihrer äußerst anregenden Mikrostudie erstmals systematisch den Briefwechsel zwischen Madame de Maintenon, der morganatischen Ehefrau Ludwigs XIV., und der Ersten Kammerdame des spanischen Königspaares, Princesse des Ursins, inmitten des Spanischen Erbfolgekrieges aus. Der präzise Blick auf ein konkretes Beispiel einer höfischen Form der Diplomatie, das keine geschlechterbezogene Ausnahmeerscheinung darstellt, sondern in Synergie mit bürokratischen Kanälen stattfand, erlaubt der Autorin generelle Aussagen zur frühneuzeitlichen Diplomatie.

  6. Diseño y Evaluación de intervenciones en organizaciones empresariales desde la dinámica de sistemas – revisión teórica. Sistemas – Revisión Teórica.

    OpenAIRE

    González Chacón, Manuel Eduardo

    2014-01-01

    Este trabajo tiene como objetivo hacer una revisión teórica desde los inicios de la Teoría General de Sistemas, hasta el desarrollo de la dinámica de sistemas, todo lo que estas dos teorías plantean, además de muchas otras teorías de las cuales estas se encuentran rodeadas y conectadas muy cercanamente, ya que partiendo del planteamiento que hizo el biólogo Ludwig Von Bertalanffy se derivaron diversas corrientes de pensamiento, todas alrededor del enfoque y pensamiento de sistemas, y de la cu...

  7. Forme di vita e relazione educativa

    Directory of Open Access Journals (Sweden)

    Viviana Segreto

    2015-05-01

    Full Text Available The aim of this paper is to show that the main object of pedagogical research is relationship among people who share the same context. The analysis follows a linguistic approach, from a theoretical and metaphysical kind of language to a language of forms of life. After the linguistic turn, particularly in Ludwig Wittgenstein, forsaking a Platonic language means throwing language in forms of life, and blending it with people and their lives. So an educational process has to leave the unique, traditional pattern to open itself to different voices of life.

  8. Applying Signature Extraction and Classification Algorithms on Express on Profiles of CD Markers and Toll Like Receptors to Classify and Predict Exposures to Various Pathogens

    Science.gov (United States)

    2016-02-10

    various time points  in more than three  replicates  each.    Host gene expression in vitro: Microarray analysis was carried out at 3‐6 time periods post...Bibliography 1. Gibb TR, Norwood DA, Jr., Woollen N, Henchal EA: Viral replication and host gene expression in alveolar macrophages...infected with Ebola virus (Zaire strain). Clin Diagn Lab Immunol 2002, 9:19-27. 2. Henchal EA, Teska JD, Ludwig GV, Shoemaker DR, Ezzell JW: Current

  9. Heinz L. Ansbacher (1904-2006).

    Science.gov (United States)

    Musty, Richard Rik E

    2007-09-01

    Heinz Ludwig Ansbacher was born in Frankfurt, Germany, on October 21, 1904. He died at his home in Burlington, Vermont, on June 22, 2006, at the age of 101 years. Alfred Adler's influence led Ansbacher to the field of psychology, where he began a lifelong scholarship on the psychology of Alfred Adler. Among Heinz's distinctions and honors were being named a Fulbright lecturer at the University of Kiel, Germany, and serving as president of the North American Society of Adlerian Psychology. Many of us will remember Professor Ansbacher as a person who lived by Adlerian principles: encouraging others while helping them to find a goal in life.

  10. Book reviews

    OpenAIRE

    NN

    2002-01-01

    It took a long time to produce, but eventually early in 2001 the first part of this extensive compendium of macromycetes appeared. It is the result of decades of work by the author, who is known as a passionate mushroom collector and painter. Ludwig has the special gift that he is able to record the beauty and diagnostic characters of a mushroom in an unique way. The first volume consists of a large-sized part, 34 x 24 cm, with the icons, and a normal sized text volume. The iconography contai...

  11. Cristianismo y naturaleza

    DEFF Research Database (Denmark)

    Cristoffanini, Pablo Rolando

    2017-01-01

    of the western world, gain increasing importance at a time of growing concern about the effects of the ecological and environmental crisis. Firstly, I introduce some ideas and images considered by eminent researchers to be the cause of the conquering, plundering and objectifying relationship to Nature. Secondly...... or entertain a stereotypical view of religion, I present some tenets of Ludwig Wittgenstein asserting the value of religion and ethics as symbolic systems that lead to different forms of life. Additionally, he maintained that religion in no way should be diminished or subjected to the rules and principles...

  12. Adherence as a language game.

    Science.gov (United States)

    Kolberg, Espen Skarstein

    2017-04-01

    Non-adherence, i.e. medication intake behavior not corresponding with agreed recommendations, is associated with increased morbidity and death, and it has been estimated that as many as 50% of patients in developed countries are not taking their medications as prescribed. But even as efforts in improving medication adherence over the years have increased, results are inconsistent, with only a minority of clinical trials showing any improvement in both adherence and clinical outcome. Since patient education is central to promoting good medication adherence, and language is integral to education, perhaps an exploration of the meaning and use of language, using the philosophy of Ludwig Wittgenstein, is in order.

  13. Verbal understanding: Integrating the conceptual analyses of Skinner, Ryle, and Wittgenstein.

    Science.gov (United States)

    Schoneberger, T

    1991-01-01

    Gilbert Ryle's (1949) and Ludwig Wittgenstein's (1953; 1958; 1974/78) conceptual analyses of verbal understanding are presented. For Ryle, the term understanding signifies simultaneously an acquired disposition and a behavioral episode. For Wittgenstein, it signifies simultaneously a skill and a criterial behavior. Both argued that episodes of understanding comprise heterogenious classes of behaviors, and that each member of such a class is neither a necessary nor a sufficient condition of understanding. Next, an approach integrating the analyses of Ryle and Wittgenstein with that of Skinner is presented. Lastly, it is argued that this integrated analysis adequately counters Parrott's (1984) argument that understanding, for Skinner, is potential behavior and not an event.

  14. [Wittgenstein and Freud].

    Science.gov (United States)

    Cabanchik, Samuel Manuel

    2005-01-01

    In this paper I present the most important limits in the reading that Ludwig Wittgenstein made of Sigmund Freud. In particular, starting from certain thematic axes (distinction causes / reasons, conception of the meaning, interpretation concept, the problem of the truth in the therapeutic treatment, the paper of the patient's conviction), I try to show that the position of Wittgenstein in front of the Freudian psychoanalysis was ambiguous: on one hand he conceives it as an example more than "philosophical mythology", but on the other hand, he is identified with the psychoanalyst and he is conceived itself as making something related with that an analyst makes.

  15. Revisiting Wittgenstein on Köhler and Gestalt psychology.

    Science.gov (United States)

    Benjafield, John G

    2008-01-01

    In an article in this journal, Nicholas Pastore rejected Ludwig Wittgenstein's critique of Wolfgang Köhler and Gestalt psychology. Pastore appears not to have appreciated Wittgenstein's argument that Köhler mistook conceptual questions for factual ones. A simi-lar confusion seems to underlie at least some aspects of contemporary neuroscience. Be that as it may, Wittgenstein has had minimal influence on the research practices of psychologists while Köhler remains influential. This outcome would not have surprised Wittgenstein, who predicted that scientists would not see his work as relevant to theirs.

  16. Transdisciplinarity Needs Systemism

    Directory of Open Access Journals (Sweden)

    Wolfgang Hofkirchner

    2017-02-01

    Full Text Available The main message of this paper is that systemism is best suited for transdisciplinary studies. A description of disciplinary sciences, transdisciplinary sciences and systems sciences is given, along with their different definitions of aims, scope and tools. The rationale for transdisciplinarity is global challenges, which are complex. The rationale for systemism is the concretization of understanding complexity. Drawing upon Ludwig von Bertalanffy’s intention of a General System Theory, three items deserve attention—the world-view of a synergistic systems technology, the world picture of an emergentist systems theory, and the way of thinking of an integrationist systems method.

  17. [Albert Reder Ritter von Schellmann (1826-1904)].

    Science.gov (United States)

    Schmidt, G; Holubar, K

    1990-01-01

    Albert Reder von Schellmann (1826-1904) was an important syphilidologist of the Vienna Medical School in the second half of the nineteenth century. He went in for the dualistic concept of the origin of syphilis and ulcer caused by soft chancre. In 1870 - Reder became head of a third dermato-syphilidologic department in the "Josephinum" in Vienna, where military surgeons got their medical education. At the same time the two full professorships of dermatosyphilidology in the Vienna General Hospital were held by Ferdinand von Hebra (1816-1880) and Carl Ludwig Sigmund von Ilanor (1810-1883).

  18. Regularities in frequency spacings of δ Scuti stars: the Kepler star KIC 9700322

    DEFF Research Database (Denmark)

    Breger, M.; Balona, L.; Lenz, P.

    2011-01-01

    In the faint star KIC 9700322 observed by the Kepler satellite, 76 frequencies with amplitudes from 14 to 29 000 ppm were detected. The two dominant frequencies at 9.79 and 12.57 d-1 (113.3 and 145.5 μHz), interpreted to be radial modes, are accompanied by a large number of combination frequencie...... with the Hobby-Eberly Telescope, which is a joint project of the University of Texas at Austin, the Pennsylvania State University, Stanford University, Ludwig-Maximilians-Universität München and Georg-August-Universität Göttingen....

  19. Melhoria do processo Hatschek, por meio de tratamento de dados históricos, para fabricação de telhas onduladas.

    OpenAIRE

    Aline Basso de Oliveira

    2010-01-01

    As telhas de cimento-amianto são utilizadas mundialmente nas construções comerciais, residenciais e industriais. O amianto foi a primeira aplicação de fibra natural em escala industrial. Esta fibra foi incorporada na forma do mineral (asbesto) como reforço de matrizes à base do cimento. O processo de fabricação de telhas de cimento-amianto mais utilizado mundialmente foi patenteado em 1900 por Ludwig Hatschek, recebendo o mesmo nome. O objetivo deste trabalho foi a melhoria do processo indust...

  20. Das Nationale Bildungspanel : Ein neues Kapitel in Deutschlands Bildungsforschung

    OpenAIRE

    Preis, Nina; Stecher, Ludwig

    2009-01-01

    Was macht eigentlich ein gutes Praktikum aus? Welche Rolle spielt ein Praktikum bei der späteren Berufswahl, und was lernen Jugendliche in einem Praktikum? Wie verhalten sich die Praktikumsanleiter? Wie nehmen es die Schülerinnen und Schüler wahr? Und wie gestaltet sich der Transfer zwischen Schule und Betrieb? Dies sind nur einige Fragen, mit denen sich die Gießener Erziehungswissenschaftler Prof. Dr. Ludwig Stecher und Dipl.-Päd. Nina Preis im Rahmen des Nationalen Bildungspanels (National ...

  1. A Praxeological Approach to Intentional Action

    Directory of Open Access Journals (Sweden)

    Futerman Alan G.

    2017-10-01

    Full Text Available The concept of Intentional Action is at the core of Praxeology, as developed by the Austrian economist Ludwig von Mises. Under this unique approach, defined as the science of human action and designed to study the field of the social sciences, Mises create “action axiom”: the contention that every acting man more satisfactory state of affairs for a Austrian scholar is able to derive the fundament human action; such as value, scale of value, scarcity, abundance, profit, loss, uncertainty and causality, among others. This paper intends to present the praxeological perspective on intentional action and its epistemologic implications; it also attempts to answer objections to this thesis.

  2. Erinnerungen. Aus dem Feldzuge der Franzosen in Russland unter Napoleon im Jahre 1812, von einem preußischen Bombardier, dem jetzigen Major Weinberger. Unveröffentlichtes Manuskript (1849), herausgegeben von Peter-Michael Berger

    OpenAIRE

    Weinberger, Friedrich Ludwig

    2012-01-01

    Friedrich Ludwig Weinberger (1794–1869) diente im Juni 1812 als Freiwilliger bei der Königsberger Garnisonsartillerie. Diese 400 Soldaten wurden von Napoleon in die Garde seiner Grande Armée zur Invasion Russlands zwangsweise eingegliedert. Als einer von nur 13 Überlebenden seiner Truppe kehrte Weinberger im März 1813 aus russischem Gewahrsam zurück. Über seine Erlebnisse beim Vormarsch, den Kämpfen, der Besetzung Moskaus, dem Rückzug und der Heimkehr verfasste er einen Bericht, den er m...

  3. Korzenie myśli libertariańskiej

    Directory of Open Access Journals (Sweden)

    Hubert Staśkiewicz

    2016-05-01

    Full Text Available In this article I discuss the roots of libertarian thought. First I draw a little-known late-scholastic philosophy of the Renaissance period. Then, the theoretical basis for the libertarian direction created: Anglo-Saxon philosophers the Age of Enlightenment and French anti-statists nineteenth century. A fundamental contribution to the popularization this philosophy played in turn: Austrian economics, which created such outstanding figures as Carl Menger, Ludwig von Mises and Chicago school of economics under the direction of Milton Friedman.

  4. Kunst-Gedanken in Tiecks «Franz Sternbalds Wanderungen»

    Directory of Open Access Journals (Sweden)

    Wolfgang Nehring

    2011-10-01

    Full Text Available Ludwig Tieck is not only the most productive and stimulating power of German Roman­ticism with respect to literature but also, largely unnoticed by his contemporaries and critics, an innovative proponent of a new art. His Sternbald goes way beyond the position of Wackenroder’s Herzensergießungen from which it started. It not only influenced the artwork of the two most important romantic painters, Philipp Otto Runge and Caspar David Fried­rich, but advocates, in a way, twentieth-century ideas of modern painting.

  5. Stochastic and infinite dimensional analysis

    CERN Document Server

    Carpio-Bernido, Maria; Grothaus, Martin; Kuna, Tobias; Oliveira, Maria; Silva, José

    2016-01-01

    This volume presents a collection of papers covering applications from a wide range of systems with infinitely many degrees of freedom studied using techniques from stochastic and infinite dimensional analysis, e.g. Feynman path integrals, the statistical mechanics of polymer chains, complex networks, and quantum field theory. Systems of infinitely many degrees of freedom create their particular mathematical challenges which have been addressed by different mathematical theories, namely in the theories of stochastic processes, Malliavin calculus, and especially white noise analysis. These proceedings are inspired by a conference held on the occasion of Prof. Ludwig Streit’s 75th birthday and celebrate his pioneering and ongoing work in these fields.

  6. Weltliche Einflüsse in der Notre-Dame-Musik? Überlegungen zu einer Klausel im Codex F

    Directory of Open Access Journals (Sweden)

    Büttner, Fred

    2002-12-01

    Full Text Available The unlimited validity of the rectilinear evolution that, according to Friedrich Ludwig, led from Notre Dame Clausula to Latin and thenceforth to French Motet was most recently questioned by Wolf Frobenius in his article "Zum genetischen Verhältnis zwischen Notre-Dame-Klauseln und ihren Motetten" (1987. Nevertheless, Frobenius does not thoroughly examine the pieces concerned, with hardly more far-reaching conclusions being attached to the priority claimed for many French Motets when comparing their concordances as Clausula and Latin Motet. With a setting of the choral melisma "ne" (Sm8 - already used by Ludwig in order to substantiate his estimation of the historical precedence of the Clausula - as an example, the point of view held by Frobenius is therefore once again subjected to critical scrutiny. Thus several traits can be established in the specifics of the Clausula that point to the field of secular music. Although this corroborates the considerations made by Frobenius, on the other hand such a result will open up new perspectives for further research into the School of Notre Dame.

    [de] Spätestens durch den Aufsatz „Zum genetischen Verhältnis zwischen Notre-Dame-Klauseln und ihren Motetten" von Wolf Frobenius (1987 wurde die uneingeschränkte Gültigkeit des geradlinigen Entwicklungsgangs, den Friedrich Ludwig von der Notre-Dame-Klausel über die lateinische bis zur franzosischen Motette zeichnete, in Frage gestellt. Jedoch bleibt Frobenius eine gründliche Untersuchung der betreffenden Stücke ebenso schuldig, wie auch an die behauptete Priorität vieler französischer Motetten gegenüber ihren Konkordanzen als Klausel und lateinische Motette kaum weiterreichende Schlußfolgerungen geknüpft werden. Anhand des „Ne"-Satzes Sm8, den bereits Ludwig exemplarisch hervorhob, um seine Auffassung von der Klausel als ältestem Stadium zu belegen, wird deshalb die Sichtweise von Frobenius noch einmal auf ihre Stichhaltigkeit

  7. Electric rivers

    International Nuclear Information System (INIS)

    McCutcheon, S.

    1992-04-01

    James Bay II, the projected Canadian hydroelectric power plant of gigantic dimensions, is to deliver its electricity to Europe: in the USA, opposition to power imports from James Bay is growing. Its realization means the flooding of an area as big as the Federal Republic of Germany; the native territory and hunting grounds of the Cree indians would be inundated. The interests of the European power industry in the James Bay project and the consequences for Europe are described in an appendix (EQHHPP project, project management Hydro-Quebec and Ludwig Boelkow Foundation, hydrogen production through electrolysis, methods for transporting hydrogen to Hamburg). (orig./HP) [de

  8. La copla de moral sefardí Azote de impíos

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    Romero, Elena

    2010-06-01

    Full Text Available Three versions of the Sephardic “Copla de moral” Azote de Impios (‘Scourge of the Wicked’ are analyzed in this article. They were all printed in the nineteenth century, in Constantinople (1858 (version A, in Leipzig (1858 (version B and in Jerusalem (1894 (version C. The Version B was included in the German Nach Jerusalem! by Ludwig Aug. Frankl is of interest as it was written with Latin letters according to a special system that reflects the sounds of the original Judeo-Spanish.En el presente artículo se lleva a cabo la edición y estudio de las tres versiones conocidas de la copla de moral sefardí titulada Azote de impíos, impresas las dos primeras en 1858 en Constantinopla (versión A y Leipzig (versión B, respectivamente, y la tercera en Jerusalén en 1894 (versión C. La versión B, inserta en el libro alemán Nach Jerusalem! de Ludwig Aug. Frankl, presenta la particularidad de estar escrita en caracteres latinos siguiendo un muy especial sistema para plasmar los sonidos del judeoespañol.

  9. Revisiting imidazolium based ionic liquids: Effect of the conformation bias of the [NTf2] anion studied by molecular dynamics simulations

    Science.gov (United States)

    Neumann, Jan; Golub, Benjamin; Odebrecht, Lisa-Marie; Ludwig, Ralf; Paschek, Dietmar

    2018-05-01

    We study ionic liquids composed of 1-alkyl-3-methylimidazolium cations and bis(trifluoromethyl-sulfonyl)imide anions ([CnMIm][NTf2]) with varying chain-length n = 2, 4, 6, 8 by using molecular dynamics simulations. We show that a reparametrization of the dihedral potentials as well as charges of the [NTf2] anion leads to an improvement of the force field model introduced by Köddermann, Paschek, and Ludwig [ChemPhysChem 8, 2464 (2007)] (KPL-force field). A crucial advantage of the new parameter set is that the minimum energy conformations of the anion (trans and gauche), as deduced from ab initio calculations and Raman experiments, are now both well represented by our model. In addition, the results for [CnMIm][NTf2] show that this modification leads to an even better agreement between experiment and molecular dynamics simulation as demonstrated for densities, diffusion coefficients, vaporization enthalpies, reorientational correlation times, and viscosities. Even though we focused on a better representation of the anion conformation, also the alkyl chain-length dependence of the cation behaves closer to the experiment. We strongly encourage to use the new NGOLP (Neumann, Golub, Odebrecht, Ludwig, Paschek) force field for the [NTf2] anion instead of the earlier KPL parameter set for computer simulations aiming to describe the thermodynamics, dynamics, and also structure of imidazolium-based ionic liquids.

  10. Vers le Sud : le voyage de Johann Georg von Dillis à travers la France, la Suisse et l'Italie en 1806

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    Josenhans, Frauke

    2011-07-01

    Full Text Available Southern France, and Provence in particular, started to lure painters as early as in the 18th century, first and foremost French ones, and then increasingly foreign painters, notably the German landscapist Johann Georg von Dillis. In 1806, he undertook a journey in the South of France in the company of the Bavarian crown prince, the future Ludwig I. Dillis' journey is known from two different sources: a group of drawings known as the Voyage pittoresque dans le Midi de la France dessiné par Dillis (Staatliche Graphische Sammlung, Munich and his unpublished correspondence with his brother Ignaz Dillis. The drawings, which were ordered by the prince as a visual souvenir of his tour, reflect Ludwig's interest in Roman Antiquity and thus include numerous views of ancient monuments, such as the Maison Carrée in Nîmes, the arc de triomphe in Orange and the ruins in Saint-Rémy-de-Provence. Apart from this group there is another body of drawings, which Dillis also made during the journey, but that he chose not to include in the Voyage pittoresque. These sheets attest to the draughtsman's attentiveness and sensibility for nature more obviously than the commissioned drawings. An official commission, the Voyage pittoresque is an exceptional artistic testimony of travel in the early 19th century. It shows that Provence became attractive for artists earlier than was previously thought.

  11. Mundo común, feminismo y mitología

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    Birulés, Fina

    2013-12-01

    Full Text Available Since the 1970s feminism has signified one of the most productive critical reconsiderations of modern political thought legacy. This article examines the questioning of modern notions of political freedom and political community that Linda Zerilli has undertaken in her reading of Hannah Arendt and Ludwig Wittgenstein. On this basis and on criticism of sexual dimorphism, the article shows the need to rethink the relationship between theory and praxis beyond its modern conception, a feature present in much of contemporary feminist theory.Desde la década de 1970 el feminismo ha significado una de las profundizaciones críticas m.s productivas del legado del pensamiento político de la modernidad. El presente artículo atiende al cuestionamiento de las modernas nociones de libertad y comunidad políticas que Linda Zerilli ha llevado a cabo en su lectura de Hannah Arendt y de Ludwig Wittgenstein. A partir de ah. y de la reciente querella en torno al diformismo sexual, se muestra la necesidad de repensar la relación entre teoría y praxis más allá de la concepción moderna, presente en buena parte de la teoría feminista contemporánea.

  12. Systems Thinking for an Economically Literate Society

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    Michael F. Reber

    2010-11-01

    Full Text Available In the US a dismal truth exists about the citizenry’s lack of understanding of economic fundamentals whether it is amongst our political leaders or our university graduates. This then leads one to ask, “What can be done to help people become literate in economics?” Perhaps the answer lies in the area of systems thinking, which is a way of thinking about the interconnections between the parts of a system and their synthesis into a unified view of the whole system. More specifically, this means incorporating systems thinking and design in primary, secondary, and tertiary curricula. In this paper, the author gives a cursory review of General Systems Theory (GST as developed by Ludwig von Bertalanffy and extended by others in the systems thinking field to illustrate the confluences of thought among Ludwig von Mises and systems scientists. From this the author argues the need for systems thinking and design in curricula and makes reference to non-prescriptive teaching and learning applications for the fostering of economic literacy.

  13. Reseñas

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    Comité Editorial

    1987-06-01

    Full Text Available Alarcón, R. (1986, Psicología, pobreza y subdesarrollo, Lima, Instituto Nacional de Investigación y Desarrollo de la Educación, 153 pgs. León, F.R., editor (1986, Psicología y realidad peruana. El aporte objetivo, Lima, Mosca Azul Editores, 298 pgs. Bittner, G., ed. (1983. PersonaJe PsychoJogie. Beitrage zur Geschichte, Theorie und Therapie. Festschrift für Ludwig J. Pongratz (Psicología personal. Contribuciones acerca de la historia, la teoría y la terapia. Escritos en honor de Ludwig J. Pongratz. Gottinga - Toronto - Zürich: Verlag für Psychologie. Dr. C. ]. Hogrefe, XII - 437 pgs. Carpintero, H. & Peiró, J.M. (dirs. (1984, La psicología en su contexto histórico. Ensayos en honor del Prof. Josef Brozek - Essays in honour Prof. Josef Brozek. Psychology in its historical context. Valencia: Monografías de la Revista de Historia de la Psicología, 396 pgs. Thomae, H. (1985, Dynamik des menschlichen Handelns. Ausgewahlte Schriften zur Psychologie 1944 - 1984 (La dinámica de la acción humana. Escritos selectos sobre psicología 1944 - 1984 . editado por Ursula M. Lehr & Franz E. Weinert. Bonn: Bouvier Verlag Herbert Grundmann, XIV - 432 pgs.

  14. Daptomycin: a novel lipopeptide antibiotic against Gram-positive pathogens

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    Andres Beiras-Fernandez

    2010-08-01

    Full Text Available Andres Beiras-Fernandez1,*, Ferdinand Vogt1,*, Ralf Sodian1, Florian Weis21Department of Cardiac Surgery, University Hospital Großhadern, Ludwig-Maximilian-University, Munich, Germany; 2Department of Anesthesiology, University Hospital Großhadern, Ludwig-Maximilian-University, Munich, Germany *Andres Beiras-Fernandez and Ferdinand Vogt contributed equally to this paperAbstract: The aim of this review is to summarize the historical background of drug resistance of Gram-positive pathogens as well as to describe in detail the novel lipopeptide antibiotic daptomycin. Pharmacological and pharmacokinetic aspects are reviewed and the current clinical use of daptomycin is presented. Daptomycin seems to be a reliable drug in the treatment of complicated skin and skin structure infections, infective right-sided endocarditis, and bacteremia caused by Gram-positive agents. Its unique mechanism of action and its low resistance profile, together with its rapid bactericidal action make it a favorable alternative to vancomycin in multi-drug resistant cocci. The role of daptomycin in the treatment of prosthetic material infections, osteomyelitis, and urogenital infections needs to be evaluated in randomized clinical trials.Keywords: daptomycin, multi-drug resistance, methicillin-resistant Staphylococcus aureus (MRSA, pneumonia, urinary tract infection, left-sided endocarditis

  15. The loop of Henle as the milestone of mammalian kindey concentrating ability: a historical review.

    Science.gov (United States)

    Koulouridis, Efstathios; Koulouridis, Ioannis

    2014-01-01

    The first description of the renal tubules is attributed to Lorenzo Bellini in 1662 and four years later Marcello Malpighi described the glomerulus. In 1842 Sir William Bowman described the capsule that surrounds the Malpighian body and its connection with the renal tubule and introduced the "excretory" hypothesis of urine formation. In the same year, Carl Ludwig introduced the "filtration-reabsorption" hypothesis of urine formation. Bowman's hypothesis was accepted by the so-called "vitalists" and Ludwig's hypothesis by the so-called "mechanists". In the middle of this confliction, Jacob Henle described in 1862 the homonymous "U" shaped loop but his discovery has neglected. In 1942 Werner Kuhn, a physical chemist, proposed that the loop of Henle may be the natural analog of the hairpin countercurrent multiplication system which concentrates urine in mammalian kidneys. In 1951 Kuhn, Hargitay and Wirz showed experimentally that the loop of Henle was the most important part of the countercurrent multiplication system of urine-concentrating mechanism in mammalian kidneys. The new theory was accepted by English-speaking scientists later, in 1958, when Carl Gottschalk and Margaret Mylle published their experimental work and proved that Kuhn's theory was correct. Gottschalk summarized the evidence of the accumulated knowledge in 1962, three centuries after the first description of renal tubules and one century after description of Henle's loop.

  16. Sevoflurane mitigates shedding of hyaluronan from the coronary endothelium, also during ischemia/reperfusion: an ex vivo animal study

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    Chen C

    2016-04-01

    Full Text Available Congcong Chen,1,3 Daniel Chappell,2,3 Thorsten Annecke,2,3 Peter Conzen,2 Matthias Jacob,2,3 Ulrich Welsch,4 Bernhard Zwissler,2 Bernhard F Becker3 1Department of Anesthesiology, Second Affiliated Hospital of Zhejiang University, Hangzhou, People's Republic of China; 2Clinic of Anesthesiology, Ludwig-Maximilians-University, Munich, Germany; 3Walter-Brendel-Centre of Experimental Medicine, Ludwig-Maximilians-University, Munich, Germany; 4Institute of Anatomy, Ludwig-Maximilians-University, Munich, Germany Abstract: Glycosaminoglycan hyaluronan (HA, a major constituent of the endothelial glycocalyx, helps to maintain vascular integrity. Preconditioning the heart with volatile anesthetic agents protects against ischemia/reperfusion injury. We investigated a possible protective effect of sevoflurane on the glycocalyx, especially on HA. The effect of pre-ischemic treatment with sevoflurane (15 minutes at 2% vol/vol gas on shedding of HA was evaluated in 28 isolated, beating guinea pig hearts, subjected to warm ischemia (20 minutes at 37°C followed by reperfusion (40 minutes, half with and half without preconditioning by sevoflurane. HA concentration was measured in the coronary effluent. Over the last 20 minutes of reperfusion hydroxyethyl starch (1 g% was continuously infused and the epicardial transudate collected over the last 5 minutes for measuring the colloid extravasation. Additional hearts were fixed by perfusion after the end of reperfusion for immunohistology and electron microscopy. Sevoflurane did not significantly affect post-ischemic oxidative stress, but strongly inhibited shedding of HA during the whole period, surprisingly even prior to ischemia. Immunohistology demonstrated that heparan sulfates and SDC1 of the glycocalyx were also preserved by sevoflurane. Electron microscopy revealed shedding of glycocalyx caused by ischemia and a mostly intact glycocalyx in hearts exposed to sevoflurane. Coronary vascular permeability of the

  17. Possíveis contribuições de Husserl e Heidegger para a clínica fenomenológica Possibles contribuciones de Husserl y Heidegger para la clínica fenomenológica Husserl´s and Heidegger´s possible contributions to clinical phenomenology

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    Virginia Moreira

    2010-12-01

    Full Text Available Este artigo tem como objetivo descrever as possíveis contribuições das filosofias de Edmund Husserl e Martin Heidegger para o desenvolvimento de uma clínica fenomenológica. Reconhece-se que Husserl, com sua Psicologia Fenomenológica, inaugura uma psicologia da subjetividade que pode servir de base para a clínica fenomenológica. O artigo também discute as contribuições e possíveis limitações das propostas clínicas de Ludwig Binswanger e Medard Boss, que procuram fundamentar-se na Analítica do Dasein de Heidegger, e propõe a fenomenologia existencial de Merleau-Ponty, que retoma o último pensamento de Husserl tendo como fio condutor o conceito de Lebenswelt, como um caminho fecundo para a clínica fenomenológica.Este artículo tiene como objetivo describir las posibles contribuciones de las filosofías de Edmund Husserl y Martin Heidegger para el desarrollo de una clínica fenomenológica. Reconoce que Husserl, con su Psicología Fenomenológica, inaugura una psicología de la subjetividad, que puede servir de base para la clínica fenomenológica. Discute las contribuciones y posibles limitaciones de las propuestas clínicas de Ludwig Binswanger y Medard Boss, que se proponen a tener como fundamentó la Analítica del Dasein de Heidegger. Sugiere la fenomenología existencial de Merleau-Ponty, que retoma el pensamiento del último Husserl teniendo como hilo conductor el concepto de Lebenswelt, como un camino fecundo para la clínica fenomenológica.This article aims to describe the possible contributions of Edmund Husserl´s and Martin Heidegger´s philosophies to the development of a phenomenological clinic. It recognizes that Husserl, with his Phenomenological Psychology, inaugurates a psychology of subjective, which may serve as basis to the phenomenological clinic. It discusses the contributions and possible limitations of Ludwig Binswanger´s and Medard Boss’s clinical proposals, which aim to be funded on Heidegger

  18. Dynamics of the concept “Man” in the history of philosophy

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    Karpina Olena Serhiyivna

    2015-10-01

    Full Text Available The article deals with the development of the category “man” in the history of philosophy. The author focuses on such periods of the philosophical thought development as the Antiquity, the Middle Ages, the Renaissance, the Modern history, the Age of the Enlightenment, German classical philosophy, and non-classical philosophy. The article analyses and compare philosophical views of such outstanding thinkers as Socrates, Aristotle, Epicurus, Titus Lucretius Carus, Thomas Aquinas, Giovanni Pico della Mirandola, Coluccio Salutati, Michel de Montaigne, Francis Bacon, John Locke, Benedict Spinoza, Blaise Pascal, Charles-Louis de Montesquieu, Voltaire, Jean-Jacques Rousseau, Immanuel Kant, Ludwig Feuerbach, Arthur Schopenhauer, Søren Kierkegaard, Friedrich Nietzsche.

  19. Beethoven's deafness, the defiance of a genius

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    Bento, Ricardo Ferreira

    2009-09-01

    Full Text Available Introduction: Ludwig van Beethoven, one of the greatest composers in History, was tormented for his whole life by a progressive deafness without definitive diagnosis. Many authors published studies about the etiologic possibilities of the deafness of the music genius with different explanations about his auditory loss. In this work, the author discusses the implications of Beethoven's progressive deafness to the creation of his word, as well as etiologic assumptions of his disease. Would Beethoven have had the same ingeniousness he showed in his symphonies if he did not have hypacusis and tinnitus? What is the influence of his deafness on his work and life? Could he have had a more precise diagnosis and specially a treatment nowadays? Would we have the brilliant composer if he had deafness today? We surely could not have!

  20. Classifications of Patterned Hair Loss: A Review.

    Science.gov (United States)

    Gupta, Mrinal; Mysore, Venkataram

    2016-01-01

    Patterned hair loss is the most common cause of hair loss seen in both the sexes after puberty. Numerous classification systems have been proposed by various researchers for grading purposes. These systems vary from the simpler systems based on recession of the hairline to the more advanced multifactorial systems based on the morphological and dynamic parameters that affect the scalp and the hair itself. Most of these preexisting systems have certain limitations. Currently, the Hamilton-Norwood classification system for males and the Ludwig system for females are most commonly used to describe patterns of hair loss. In this article, we review the various classification systems for patterned hair loss in both the sexes. Relevant articles were identified through searches of MEDLINE and EMBASE. Search terms included but were not limited to androgenic alopecia classification, patterned hair loss classification, male pattern baldness classification, and female pattern hair loss classification. Further publications were identified from the reference lists of the reviewed articles.

  1. Hair biology and its comprehensive sequence in female pattern baldness: clinical connotation diagnosis and differential diagnosis--Part II.

    Science.gov (United States)

    Sehgal, Virendra N; Srivastava, Govind; Aggarwal, Ashok K; Midha, Rashmi

    2013-01-01

    Hair can become a source of concern when there is a change in its texture, number, and thinning. Although female pattern baldness is common, it has received little attention compared with male pattern baldness. Thinning that affects the vertex is insidious and progressive. Hair loss in women has accordingly been interpreted and classified differently than that in men. The Ludwig scale is the most accepted classification. The gross anatomy and the general microanatomy of the hair follicle, including that of the anagen, catagen, and telogen phase, are presented. The hair growth cycle, encompassing anagen, catagen, telogen, exogen, and kenogen, is also discussed to address pattern hair loss in women and provide therapeutic options that are currently available.

  2. Towards Quantifying a Wider Reality: Shannon Exonerata

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    Robert E. Ulanowicz

    2011-10-01

    Full Text Available In 1872 Ludwig von Boltzmann derived a statistical formula to represent the entropy (an apophasis of a highly simplistic system. In 1948 Claude Shannon independently formulated the same expression to capture the positivist essence of information. Such contradictory thrusts engendered decades of ambiguity concerning exactly what is conveyed by the expression. Resolution of widespread confusion is possible by invoking the third law of thermodynamics, which requires that entropy be treated in a relativistic fashion. Doing so parses the Boltzmann expression into separate terms that segregate apophatic entropy from positivist information. Possibly more importantly, the decomposition itself portrays a dialectic-like agonism between constraint and disorder that may provide a more appropriate description of the behavior of living systems than is possible using conventional dynamics. By quantifying the apophatic side of evolution, the Shannon approach to information achieves what no other treatment of the subject affords: It opens the window on a more encompassing perception of reality.

  3. [Pathology and pathologists in fiction revisited].

    Science.gov (United States)

    Nizze, H

    2008-11-01

    Pathology and pathologists are rarely the subjects of works of fiction. In the existing sources, the kind of representation naturally depends on the occupations and attitudes of the respective authors. The surgeon and gynecologist Carl Ludwig Schleich recollected Rudolf Virchow's free and easy handling of an autopsy assistant and his simultaneous understanding for a mourning husband. The dermatologist Gottfried Benn processed his disturbing impressions of pathology as an expressionistic dialogue between professor and students, with a violent ending. The writer and dramatic adviser Günther Weisenborn recalled unpleasant details about the autopsy course in his earlier medical studies, which he linked with individual views about the life of a deceased young woman. Praise, so to speak, to the dissecting pathologist have been sensitively written by the lawyer Maxence van der Meersch and by the surgeon Peter Bamm. Finally, the bestselling novelist Arthur Hailey gives an excellent fictional portrayal of the microscopic pathologist in The Final Diagnosis.

  4. 5 years of experience with a large-scale mentoring program for medical students

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    Pinilla, Severin

    2015-02-01

    Full Text Available In this paper we present our 5-year-experience with a large-scale mentoring program for undergraduate medical students at the Ludwig Maximilians-Universität Munich (LMU. We implemented a two-tiered program with a peer-mentoring concept for preclinical students and a 1:1-mentoring concept for clinical students aided by a fully automated online-based matching algorithm. Approximately 20-30% of each student cohort participates in our voluntary mentoring program. Defining ideal program evaluation strategies, recruiting mentors from beyond the academic environment and accounting for the mentoring network reality remain challenging. We conclude that a two-tiered program is well accepted by students and faculty. In addition the online-based matching seems to be effective for large-scale mentoring programs.

  5. Superconductor come on the market. Pt. 2

    International Nuclear Information System (INIS)

    Heinzelmann, E.

    1995-01-01

    Switzerland has the leading position in the field of high-temperature superconductors (HTS). The research group of Professor Ott at the ETH Zurich holds the international high-temperature record with 140 C. The company ABB with its powerful current limiter is one of the world's leading enterprises in this field. The ceramic bands developed by professor Fluekiger of the University of Geneve conduct electric current free of loss with such an efficiency that can only by reached by Japan and the USA. In order to use the applications of the HTS-technology for series production, special types of ceramic are required as they are being developed by professor Ludwig J. Gaukler and his team at the ETH Zurich. (orig.) [de

  6. Dynamics of macro-observables and space-time inhomogeneous Gibbs ensembles

    International Nuclear Information System (INIS)

    Lanz, L.; Lupieri, G.

    1978-01-01

    The relationship between the classical description of a macro-system and quantum mechanics of its particles is considered within the framework recently developed by Ludwig. A procedure is given to define probability measures on the trajectory space of a macrosystem which yields a statistical description of the dynamics of a macrosystem. The basic tool in this treatment is a new concept of space-time inhomogeneous Gibbs ensemble, defined in N-body quantum mechanics. In the Gaussian approximation of the probabilities the results of Zubarev's theory based on the ''nonequilibrium statistical operator'' are recovered. The present ''embedding'' of the description of a macrosystem inside the N-body theory allows for a joint description of a macrosystem and a microsubsystem of it, and a ''macroscopical'' calculation of the statistical operator of the microsystem is indicated. (author)

  7. Common Frontiers of the Exact Sciences and the Humanities

    Science.gov (United States)

    Hiebert, Erwin N.

    The physicist Franz Serafin Exner (1849-1926) was a prominent Austrian spokesman for the new developments that were coupled with turn-of-the-century experiments and theories related to entropy thermodynamics, the internally structured atom, quantum theory, and relativity. The Exner circle found its inspiration in the intellectual world of Ludwig Boltzmann and his teachers, colleagues, and students. Cross-discipline discussions on common and divergent frontiers of the exact sciences and the humanities meaningfully converged on the significance, comparison, and transfer of concepts such as the laws of nature, causality, probability, and chance. Oswald Spengler's Decline of the West, with its pessimistic, subjectivistic, and negative science-directed messages provided Exner with the opportunity to sharpen his support for the new scientific trends in physics - thus to champion the search for objective truth.

  8. Occurrence and distribution of triclosan in the German Bight (North Sea)

    Energy Technology Data Exchange (ETDEWEB)

    Zhiyong, Xie [GKSS Research Centre Geesthacht, Institute for Coastal Research, Max-Planck Strasse 1, D-21502 Geesthacht (Germany); Institute of Ecology and Environmental Chemistry, University of Lueneburg, Scharnhorststrasse 1, D-21335 Lueneburg (Germany)], E-mail: zhiyong.xie@gkss.de; Ebinghaus, Ralf; Floeser, Goetz; Caba, Armando [GKSS Research Centre Geesthacht, Institute for Coastal Research, Max-Planck Strasse 1, D-21502 Geesthacht (Germany); Ruck, Wolfgang [Institute of Ecology and Environmental Chemistry, University of Lueneburg, Scharnhorststrasse 1, D-21335 Lueneburg (Germany)

    2008-12-15

    The potential of triclosan (TCS) acting as an endocrine disruptor has led to growing concern about the presence of TCS in the environment. In this study, seawater samples were collected from the German Bight during sampling campaigns conducted with the German research ships Gauss and Ludwig Prandtl. TCS was determined both in the dissolved phase and in the suspended particulate matters with concentrations ranging 0.8-6870 pg L{sup -1} and <1-95 pg L{sup -1}, respectively. High concentrations of TCS were present in the estuaries of the Elbe and the Weser, indicating significant input of TCS by the river discharge. The correlation coefficient (R{sup 2}) between the dissolved concentration and salinity was 0.79 for the data obtained from the Gauss cruise, showing an obvious declining trend from the coast to the open sea. - Investigation with coastal survey reveals distribution of triclosan in marine waters.

  9. Occurrence and distribution of triclosan in the German Bight (North Sea)

    International Nuclear Information System (INIS)

    Xie Zhiyong; Ebinghaus, Ralf; Floeser, Goetz; Caba, Armando; Ruck, Wolfgang

    2008-01-01

    The potential of triclosan (TCS) acting as an endocrine disruptor has led to growing concern about the presence of TCS in the environment. In this study, seawater samples were collected from the German Bight during sampling campaigns conducted with the German research ships Gauss and Ludwig Prandtl. TCS was determined both in the dissolved phase and in the suspended particulate matters with concentrations ranging 0.8-6870 pg L -1 and -1 , respectively. High concentrations of TCS were present in the estuaries of the Elbe and the Weser, indicating significant input of TCS by the river discharge. The correlation coefficient (R 2 ) between the dissolved concentration and salinity was 0.79 for the data obtained from the Gauss cruise, showing an obvious declining trend from the coast to the open sea. - Investigation with coastal survey reveals distribution of triclosan in marine waters

  10. Jogos de linguagem/jogos de verdade: de Wittgenstein a Foucault

    Directory of Open Access Journals (Sweden)

    Elza Ibrahim

    2014-08-01

    Full Text Available This article discusses the constitution of the subject through the truth games and the language games problematized, respectively, by Michel Foucault and Ludwig Wittgenstein, taking as a conducting wire the implications of language in the practices produced in a psychiatric hospital with the human being considered not to be regularly punished. Therefore, we present the objectivist vision of reality and the representational language vision as opposed to the constructivist view of reality and the pragmatic language itself. According to this latter view, the reality is produced by the language through the language games which are historically contextualized. Thus, we are talking about unique subjects. In this context, we bring to the discussion the notion of truth problematized by Foucault as a field of possibilities, who thinks it is so only in the contingency of history that the subject is constituted: as the language, he is the product of multiple social practices.

  11. Reviews in Modern Astronomy: Vol. 17: The Sun and Planetary Systems - Paradigms for the Universe

    Science.gov (United States)

    Schielicke, Reinhard E.

    2004-09-01

    Volume 17 continues the Reviews of Modern Astronomy with fourteen invited reviews and Highlight Contributions which were presented during the International Scientific Conference of the Society on "The Sun and Planetary Systems", held at Freiburg, Germany, September 15 to 20, 2003. The Karl Schwarzschild medal 2003 was awarded to Professor Erika Boehm-Vitense, Seattle, USA. Her lecture with the title "What Hyades F Stars tell us about Heating Mechanisms in Stellar Transition Layers and Coronae" opened the meeting. The talk presented by the Ludwig Biermann-Prize winner 2003, Dr Luis R. Bellot Rubio, Freiburg i. Br., Germany, dealt with the topic "The Structure of Sunspots as Inferred from Spectropolarimetric Measurements". Other contributions to the meeting published in this volume discuss, among other subjects, solar physics, formation of planets and interferometric imaging in astronomy.

  12. Reviews in Modern Astronomy 12, Astronomical Instruments and Methods at the turn of the 21st Century

    Science.gov (United States)

    Schielicke, Reinhard E.

    The yearbook series Reviews in Modern Astronomy of the Astronomische Gesellschaft (AG) was established in 1988 in order to bring the scientific events of the meetings of the society to the attention of the worldwide astronomical community. Reviews in Modern Astronomy is devoted exclusively to the invited Reviews, the Karl Schwarzschild Lectures, the Ludwig Biermann Award Lectures, and the highlight contributions from leading scientists reporting on recent progress and scientific achievements at their respective research institutes. Volume 12 continues the yearbook series with 16 contributions which were presented during the International Scientific Conference of the AG on ``Astronomical Instruments and Methods at the Turn of the 21st Century'' at Heidelberg from September 14 to 19, 1998

  13. La crítica del racionalismo y la pertinencia de la religiosidad en el mundo moderno (The critique of rationalism and the pertinence of religiousness in the modern world

    Directory of Open Access Journals (Sweden)

    H. C. F. Mansilla

    2008-06-01

    Full Text Available La crítica racionalista de los fenómenos religiosos se originó en la Antigüedad clásica y posteriormente en la Ilustración y fue continuada hasta el postmodernismo actual. Decisivos han sido los aportes de Ludwig Feuerbach, Karl Marx, Sigmund Freud y Friedrich Nietzsche. Estos análisis de la religión, centrados en el desilusionamiento sistemático, son reconstruidos someramente y sometidos a crítica. El artículo plantea la necesidad de una religiosidad intelectual, pero se distancia del primer protestantismo (Martín Lutero y de sus consecuencias socio-políticas. Se postula la continuada necesidad de un primer principio que dé sentido a todos los otros fenómenos y que evite el relativismo total.

  14. A New Philosophical Underpinning of Macromarketing Theories

    DEFF Research Database (Denmark)

    Skytte, Hans

    2014-01-01

    and concepts: “language is autonomous”, “concept”, “seeing as”, “language-games”, etc. In this paper these philosophical thoughts and concepts combine so that they over time form recursive processes which spiral. These processes are taken as the philosophical foundation for researching the language and actions...... of the social actors in marketing systems. The unit of analysis for marketing systems and macromarketing issues is the idea in the recursive process and spiral. The introduction gives a brief overview of what is understood by macromarketing. Followed by a thorough explanation of many of Wittgenstein......This paper proposes a new philosophical foundation for analyzing macromarketing issues, and for further development of macromarketing theory, building on the language philosophy developed by the German/British philosopher Ludwig Wittgenstein. The building blocks are a number philosophical thoughts...

  15. Depending on Ethics

    DEFF Research Database (Denmark)

    Christensen, Anne-Marie Søndergaard

    2007-01-01

    According to the standard reception, Kierkegaard thinks of ethics as a possible stage in human life. In this paper, I do not want to contest this interpretation, but I will argue that it often overlooks how the concept of ethics plays another vital role in Kierkegaard's thinking, namely...... that of establishing a necessary connection between ethics and certain forms of philosophy. To avoid the unfruitful thinking of ‘the speculation', the philosopher must accept that her vantage point is given, not in pure objectivity, but in the fact that she is this particular human being; that is, the ethical...... dimension of her life. In this way, Kierkegaard claims that any philosophy concerning human existence must also include ethical considerations. This is a view also held by Ludwig Wittgenstein, but a comparison of the two philosophers shows that even if Kierkegaard finds such fruitful philosophy possible, he...

  16. "Cosmomorphistic geometry" in the unconscious geometry of Johannes Kepler

    Science.gov (United States)

    Adam, Adolf

    Some mathematical aspects of the Music theory by Johannes Kepler are discussed, paying a special attention to the book "De harmonice mundi". Other scientists interested in Music theory are mentioned throughout the paper: The Pythagorean school, Klaudios Ptolemaios, Leonard Euler, Gottfried Wilhelm Leibniz, Christian von Goldbach, Hermann Ludwig Ferdinand von Helmholz, Karl Friedrich Gauss. The relation with the ancient chinese schools of cosmography has been discussed: From the the Pythagorean to the ancient Chinese schools of cosmography we find arithmo-geometrical applications of numbers which are emblematic, hold meaning or represent the essence of things, the author writes. It was Johannes Kepler who taught us this "transconstructive method" of forming classical and ancient begginings of structuralistic thinking into a system from which deductions can readily be made.

  17. Estoniasse sõidab teatribuss

    Index Scriptorium Estoniae

    2007-01-01

    Septembris sõidutab Virumaa teatribuss soovijaid neljale Rahvusooperi Estonia etendusele: lastelavastus "Pipi! Nuki! Puhh!" 12. sept., operett "Viini veri" 13. sept., ooper "Tuhkatriinu" 14. sept., ballett "Sülfiid" 15. septembril. Rahvusooper Estonia alustab 102. hooaega: traditsiooniline turupäev 9. sept., Ludwig Minkuse ballett "Don Quijote" (lavastaja Tiit Härm) 4. okt., A. Dvoraki "Reekviem" Tallinnas 1. nov., Tartus 2. nov ja Pärnus 3. nov., Neeme Kuninga lavastatud G. Verdi ooper "Rigoletto" 9. nov., Lehari "Lõbus Lesk" 28. nov., Tibor Kocsaki lasteballett "Lumivalgeke ja seitse pöialpoissi" (lavastaja Gyula Harangozo) 1. veebr. 2008, G. Verdi ooperi "Simon Boccanegra" kontsertettekanne 15. märtsil, muusikali "Minu veetlev leedi" (lavastaja Ago-Endrik Kerge) esietendus 3. apr., R. Wagneri ooper "Tristan ja Isolde" (lavastaja Neeme Kuningas) 17. mail (info: www. opera.ee)

  18. How History Helped Einstein in Special Relativity

    Science.gov (United States)

    Martinez, Alberto

    2013-04-01

    I will discuss how the German intellectual movement known as ``critical history'' motivated several physicists in the late 1900s to radically analyze the fundamental principles of mechanics, leading eventually to Einstein's special theory of relativity. Eugen Karl Dühring, Johann Bernhard Stallo, Ludwig Lange, and Ernst Mach wrote critical histories of mechanics, some of which emphasized notions of relativity and observation, in opposition to old metaphysical concepts that seemed to infect the foundations of physics. This strand of critical history included the ``genetic method'' of analyzing how concepts develop over time, in our minds, by way of ordinary experiences, which by 1904 was young Albert Einstein's favorite approach for examining fundamental notions. Thus I will discuss how history contributed in Einstein's path to relativity, as well as comment more generally on Einstein's views on history.

  19. Boundary entropy of one-dimensional quantum systems at low temperature

    International Nuclear Information System (INIS)

    Friedan, Daniel; Konechny, Anatoly

    2004-01-01

    The boundary β function generates the renormalization group acting on the universality classes of one-dimensional quantum systems with boundary which are critical in the bulk but not critical at the boundary. We prove a gradient formula for the boundary β function, expressing it as the gradient of the boundary entropy s at fixed nonzero temperature. The gradient formula implies that s decreases under renormalization, except at critical points (where it stays constant). At a critical point, the number exp(s) is the 'ground-state degeneracy', g, of Affleck and Ludwig, so we have proved their long-standing conjecture that g decreases under renormalization, from critical point to critical point. The gradient formula also implies that s decreases with temperature, except at critical points, where it is independent of temperature. It remains open whether the boundary entropy is always bounded below

  20. Neuroscience in Nazi Europe Part III: victims of the Third Reich.

    Science.gov (United States)

    Zeidman, Lawrence A; Kondziella, Daniel

    2012-11-01

    In Part I, neuroscience collaborators with the Nazis were discussed, and in Part II, neuroscience resistors were discussed. In Part III, we discuss the tragedy regarding european neuroscientists who became victims of the Nazi onslaught on “non-Aryan” doctors. Some of these unfortunate neuroscientists survived Nazi concentration camps, but most were murdered. We discuss the circumstances and environment which stripped these neuroscientists of their profession, then of their personal rights and freedom, and then of their lives. We include a background analysis of anti-Semitism and Nazism in their various countries, then discuss in depth seven exemplary neuroscientist Holocaust victims; including Germans Ludwig Pick, Arthur Simons, and Raphael Weichbrodt, Austrians Alexander Spitzer and Viktor Frankl, and Poles Lucja Frey and Wladyslaw Sterling. by recognizing and remembering these victims of neuroscience, we pay homage and do not allow humanity to forget, lest this dark period in history ever repeat itself.

  1. “Bateson’s Butterfly”: Observable monitoring of emerging factors for continuity and social change

    Directory of Open Access Journals (Sweden)

    Vivina Salvetti

    2017-12-01

    Full Text Available The butterfly model inspired by Gregory Bateson´s “ecology of mind” retrieves the anthropological tradition of visual field data recording that began in 1898 and responds to Ludwig von Bertalanffy’s General System Theory and its principles of isomorphism and logical hierarchy between differentiated systems as a requirement for transdisciplinary analysis of phenomena. The spiral flow of non-dialectical character between complementary systems, where each turn of the helix represents the momentum resulting from attraction to an open set of initial conditions, introduces the emergence of particular phenomena aimed at metarule of change that feeds the entire system. Topological modeling supports replacing elements once their logic correspondence is saved, and is presented as an operational tool to address social phenomena of stability and change.

  2. Normal Modes of Magnetized Finite Two-Dimensional Yukawa Crystals

    Science.gov (United States)

    Marleau, Gabriel-Dominique; Kaehlert, Hanno; Bonitz, Michael

    2009-11-01

    The normal modes of a finite two-dimensional dusty plasma in an isotropic parabolic confinement, including the simultaneous effects of friction and an external magnetic field, are studied. The ground states are found from molecular dynamics simulations with simulated annealing, and the influence of screening, friction, and magnetic field on the mode frequencies is investigated in detail. The two-particle problem is solved analytically and the limiting cases of weak and strong magnetic fields are discussed.[4pt] [1] C. Henning, H. K"ahlert, P. Ludwig, A. Melzer, and M.Bonitz. J. Phys. A 42, 214023 (2009)[2] B. Farokhi, M. Shahmansouri, and P. K. Shukla. Phys.Plasmas 16, 063703 (2009)[3] L. Cândido, J.-P. Rino, N. Studart, and F. M. Peeters. J. Phys.: Condens. Matter 10, 11627--11644 (1998)

  3. Ethic / Aesthetic Aspect of Emotions Ecologicity in the Works of Art

    Directory of Open Access Journals (Sweden)

    Виктор Иванович Шаховский

    2015-12-01

    Full Text Available The article aims to demonstrate the mechanisms of interpretation of emotional theme depending on how it is actualized in the text. The object of investigation is an ethic / aesthetic aspect, which is the most important element of the text analysis from the point of view of its ecology / non-ecology. Joy as a variation of liberty theme is analyzed in Ludwig van Beethoven Symphony No. 9 “Choral,” Anthony Burgess’s A Clockwork Orange and S. Kubrick’s movie with the same title. The article shows how the theme of joy (liberty specified in the instrumental (music text in its lofty ethical interpretation becomes aggressively dissolute in the literary text and denies ethical values. The authors come to a conclusion that the variation mode of emotions ecologicity depends on the ambivalence of the situations they are actualized in.

  4. The history of theoretical, material and computational mechanics mathematics meets mechanics and engineering

    CERN Document Server

    2014-01-01

    This collection of 23 articles is the output of lectures in special sessions on “The History of Theoretical, Material and Computational Mechanics” within the yearly conferences of the GAMM in the years 2010 in Karlsruhe, Germany, 2011 in Graz, Austria, and in 2012 in Darmstadt, Germany; GAMM is the “Association for Applied Mathematics and Mechanics”, founded in 1922 by Ludwig Prandtl and Richard von Mises. The contributions in this volume discuss different aspects of mechanics. They are related to solid and fluid mechanics in general and to specific problems in these areas including the development of numerical solution techniques. In the first part the origins and developments of conservation principles in mechanics and related variational methods are treated together with challenging applications from the 17th to the 20th century. Part II treats general and more specific aspects of material theories of deforming solid continua and porous soils. and Part III presents important theoretical and enginee...

  5. Weismann, Wittgenstein and the homunculus fallacy.

    Science.gov (United States)

    Smit, Harry

    2010-09-01

    A problem that has troubled both neo-Darwinists and neo-Lamarckians is whether instincts involve knowledge. This paper discusses the contributions to this problem of the evolutionary biologist August Weismann and the philosopher Ludwig Wittgenstein. Weismann discussed an empirical homunculus fallacy: Lamarck's theory mistakenly presupposes a homunculus in the germ cells. Wittgenstein discussed a conceptual homunculus fallacy which applies to Lamarck's theory: it is mistaken to suppose that knowledge is stored in the brain or DNA. The upshot of these two fallacies is that instincts arise through a neo-Darwinian process but are not cognitions in the sense that they involve (the recollection of stored) knowledge. Although neo-Lamarckians have rightly argued that learning processes may contribute to the development of instincts, their ideas about the role of knowledge in the evolution and development of instincts are mistaken. Copyright © 2010 Elsevier Ltd. All rights reserved.

  6. The Joint Philosophical Program of Russell and Wittgenstein and Its Demise

    Directory of Open Access Journals (Sweden)

    Nikolay Milkov

    2013-03-01

    Full Text Available Between April and November 1912, Bertrand Russell and Ludwig Wittgenstein were engaged in a joint philosophical program. Wittgenstein’s meeting with Gottlob Frege in December 1912 led, however, to its dissolution—the joint program was abandoned. Section 1 of this paper outlines the key points of that program, identifying what Russell and Wittgenstein each contributed to it. The second section determines precisely those features of their collaborative work that Frege criticized. Finally, building upon the evidence developed in the first two sections, section 3 recasts along previously undeveloped lines Wittgensein’s logical–philosophical discoveries in the two years following his encounter with Frege in 1912. The paper concludes, in section 4, with an overview of the dramatic consequences the Frege–Wittgenstein critique had for Russell’s philosophical development.

  7. Was ein Wort bedeutet, kann ein Satz nicht sagen: Zur Bedeutung der Terminologiearbeit für die Technische Kommunikation und das Fachtextübersetzen

    Directory of Open Access Journals (Sweden)

    Klaus-Dirk Schmitz

    2010-05-01

    Full Text Available Einleitung: Dieser Beitrag geht von einem Zitat des österreichisch-britischen Philosophen Ludwig Wittgenstein aus und bezeiht sich auf seine Aussagen über Wörter und Sätze. Zielsetzung: Analyse und Diskussion der Relevanz von WittgensteinsAussage für die Terminologiearbeit in der Technischen Kommunikation und beim Fachübersetzen. Methode: Kritische Analyse und Betrachtung. Ergebnis: Neben den terminologischen Grundbegriffen Begriff, Benennung und Gegenstand werden vor allem die Definition als Begriffsbeschreibung sowie die Kriterien zur Bildung von Benennungen untersucht. Schlussfolgerung: Das Zitat von Wittgenstein lässt viele Interpretationen zu. Für die Technische Kommunikation und das Fachübersetzen muss aber die Definition (Satz den Begriff hinter der Benennung (Wort erklären. Idealerweise ist aber die Benennung so transparent, dass dadurch schon die Begriffsklärung erfolgt.

  8. Resenha do Livro: “Etnomatemática em movimento”-Gelsa Knijnik Fernanda Wanderer-Ieda M. Giongo- Claudia G. Duarte- Ed. Autêntica-Coleção Tendências em Educação Matemática, 2012

    Directory of Open Access Journals (Sweden)

    Marco Aurélio Kistemann Jr.

    2013-03-01

    Full Text Available Nesta resenha apresentamos o mais novo livro da Coleção Tendências em Educação Matemática no qual as autoras retomam questões do pensamento etnomatemático, colocando-o em movimento, apoiando-se nos pensamentos dos filósofos Michel Foucault e Ludwig Wittgenstein para propor ideias e valorizar novas formulações visando à gênese de distintos modos de escolarização, além dos já reificados nas práticas escolares e curriculares, com base numa perspectiva etnomatemática abordada em diversos contextos, identificando os jogos de linguagem matemáticos, muitas vezes secundarizados ou marginalizados nas práticas pedagógicas em curso.

  9. Trust and truth: uncertainty in health care practice.

    Science.gov (United States)

    Tyreman, Stephen

    2015-06-01

    Uncertainty is the ubiquitous presence across health care. It is usually understood in terms of decision making, 'knowing' the correct diagnosis or understanding how the human body works. Using the work of Ludwig Wittgenstein, Georges Canguilhem and Tim Ingold, I outline a story of journeying and habitation, and argue that while uncertainty for practitioners may be about enhancing theoretical knowledge, for patients it is about knowing how to act in a taken-for-granted and largely unconscious way in a world that has become uncertain, and in which the main tool of action, the human body, no longer functions with the certainty it once had. In this situation, the role of the practitioner is first and foremost to recognize the uncertainty that has emerged in the patient's 'habitation' and to reassure them by enabling them to have a new or restored confidence in their body so that they can act with certainty. © 2015 John Wiley & Sons, Ltd.

  10. “The Role of Innocent Guilt in Conflict Reconciliation”

    DEFF Research Database (Denmark)

    Christensen, Anne-Marie Søndergaard

    2013-01-01

    The phenomenon of ‘innocent guilt’ regards cases where people feel guilty without being responsible for the wrongdoing or suffering at which the guilt is directed. The aim of this article is to develop a consistent account of innocent guilt and show how it may arise in the aftermath of conflicts....... In order to do this, innocent guilt is contrasted with guilt and collective guilt, and the account is substantiated by drawing on the writings of Ludwig Wittgenstein and Emmanuel Levinas,who both consider the phenomenon of innocent guilt a necessary element in the fundamental structure of the ethical...... subject.These thinkers, furthermore, show a connection between guilt and possible victims of wrongdoing, rather than between guilt and personal acts of wrongdoing. Innocent guilt may thus appear in the aftermath of conflicts as an ethical and emotional response to the fact of finding oneself in a post-conflict...

  11. The mathematics of the modernist villa architectural analysis using space syntax and isovists

    CERN Document Server

    Ostwald, Michael J

    2018-01-01

    This book presents the first detailed mathematical analysis of the social, cognitive and experiential properties of Modernist domestic architecture. The Modern Movement in architecture, which came to prominence during the first half of the twentieth century, may have been famous for its functional forms and machine-made aesthetic, but it also sought to challenge the way people inhabit, understand and experience space. Ludwig Mies van der Rohe’s buildings were not only minimalist and transparent, they were designed to subvert traditional social hierarchies. Frank Lloyd Wright’s organic Modernism not only attempted to negotiate a more responsive relationship between nature and architecture, but also shape the way people experience space. Richard Neutra’s Californian Modernism is traditionally celebrated for its sleek, geometric forms, but his intention was to use design to support a heightened understanding of context. Glenn Murcutt’s pristine pavilions, seemingly the epitome of regional Modernism, actu...

  12. Gli atomi di Boltzmann

    CERN Document Server

    Lindley, David

    2002-01-01

    Ludwig Boltzmann (1844-1906) è il fisico e matematico austriaco che negli ultimi decenni dell'Ottocento e ancora ai primi del Novecento lottò contro l'opinione dominante tra gli scienziati dell'epoca per affermare la teoria atomica della materia. È noto come con Albert Einstein e fino a oggi la fisica si sia sviluppata e abbia celebrato i propri trionfi lungo le linee anticipate da Boltzmann. La controversia con Mach non riguardava soltanto l'esistenza degli atomi, ma l'intero modo di fare fisica che Boltzmann non riteneva di dover limitare allo studio di quantità misurabili, introducendo invece spiegazioni più elaborate basate su ipotesi più ampie.

  13. Atoms and Ions; Universality, Singularity and Particularity:. on Boltzmann's Vision a Century Later

    Science.gov (United States)

    Fisher, Michael

    2008-12-01

    Ludwig Boltzmann died by his own hand 101 years ago last September. He was a passionate believer in atoms: underlying thermodynamics, he felt, lay a statistical world governed by the mechanics of individual particles. His struggles against critics -- "Have you ever seen an atom?" taunted Ernst Mach -- left him pessimistic. Nevertheless, following Maxwell and clarified by Gibbs, he established the science of Statistical Mechanics. But today, especially granted our understanding of critical singularities and their universality, how much do atomic particles and their charged partners, ions, really matter? The answers we have also met opposition. But Boltzmann would have welcomed the insights gained and approved of applications of statistical dynamics to biology, sociology, and other enterprises. Note from Publisher: This article contains the abstract only.

  14. An enigmatic graffito from the sun temple of Nyuserre and the meaning of the so-called “slaughterhouse”

    Directory of Open Access Journals (Sweden)

    Massimiliano Nuzzolo

    2016-12-01

    Full Text Available For a long time the presence of a “slaughterhouse” in the sun temple of Nyuserre has been taken for granted as the result of the investigation conducted by Ludwig Borchardt in Abu Ghurab in 1898–1901. However, several pieces of archaeological and textual evidence, including the documents from the Abusir papyri, which are contemporary with the sun temples, challenge this reconstruction. An important element in this discussion may probably come from the correct reading and interpretation of a hieratic inscription found inside the so-called “slaughterhouse” and later on completely forgotten. To this inscription, and the important institutions mentioned therein, we shall pay attention in this article.

  15. Academic Training: The World of Quantum Matter

    CERN Multimedia

    Françoise Benz

    2006-01-01

    2005-2006 ACADEMIC TRAINING PROGRAMME LECTURE SERIES 23, 24, 25, 26 January 2006 from 11:00 to 12:00 - Main Auditorium, bldg. 500 The World of Quantum Matter M. WEIDEMUELLER / Albert-Ludwigs-Universität Freiburg In my lecture series, I will present the recent spectacular advances in the field of quantum gases and macroscopic quantum physics. A variety of subjects will be covered including Bose condensates and degenerate Fermi gases, ultracold molecules and chemistry near absolute zero, Rydberg gases, single-atom manipulation, quantum information processing, as well as applications of cold atoms as precision targets. The topics of the lectures are: Physics near absolute zero Bose condensation and Fermi degeneracy Molecules, Rydberg gases and other exotic species Single-atom manipulation, quantum information processing and ultracold atoms as targets in storage rings. ENSEIGNEMENT ACADEMIQUE ACADEMIC TRAINING Françoise Benz 73127 academic.training@cern.ch If you wish to participate in one of the f...

  16. Rotation therapy for maniacs, melancholics and idiots: theory, practice and perception in European medical and literary case histories.

    Science.gov (United States)

    Dickson, Sheila

    2018-03-01

    This article examines the development and use of rotation therapy in the emerging field of psychiatry at the beginning of the 19th century, and the cross-fertilization between British, Irish, German, French and other European proponents of 'Cox's Swing'. Its short-lived popularity is linked to prevalent Enlightenment thought, to the development of an industrial and technological society, to the modern medical theories of irritability, and to the new practice of 'moral management' of the mentally ill. Case studies documenting the use of the Swing are considered from these perspectives, and are compared with contemporary public reactions in the form of publications in newspapers and of a literary text by German Romantic author Ludwig Achim von Arnim.

  17. On trying to say what “goes without saying”. Wittgenstein on certainty and ineffability

    Directory of Open Access Journals (Sweden)

    Anna Boncompagni

    2014-04-01

    Full Text Available This paper offers a philosophical outlook on the subject of the communication of certainty and uncertainty, by focusing on the later Ludwig Wittgenstein’s image of “hinges”. Hinges are basic common sense certainties which ordinarily “go withoutsaying”. In a sense, they even require not to be said. Lingering over the debate on the ineffability of hinges which is at the core of the Wittgensteinian secondary literature, but also hinting at some studies in psychopathology, the paper argues that in extraordinary contexts to assert explicitly a hinge-certainty is possible and maybe important, while in ordinary contexts certainty can only be communicated through silence: when a certainty which “goes without saying” is explicitly said, the situation paradoxically results in uncertainty.

  18. O neoliberalismo como um dos fundamentos da educação domiciliar

    Directory of Open Access Journals (Sweden)

    Romualdo Luiz Portela de Oliveira

    Full Text Available Resumo Este artigo tem como objetivo analisar o neoliberalismo como um dos fundamentos da educação domiciliar, fenômeno de interesse crescente no Brasil, dada a tentativa de regulamentá-lo no país. Para tanto, foram tomados como referência três autorizados representantes do neoliberalismo: Friedrich Hayek; Milton Friedman e Ludwig von Mises e a reiterada preocupação destes com as liberdades, sobretudo as individuais. O artigo argumenta que o neoliberalismo se apresenta como uma das correntes teóricas que também dá suporte ao homeschooling, tendo como ponto crucial de sua fundamentação a rejeição da compulsoriedade da educação escolar, o que gera fortes implicações para o debate educacional, principalmente como desafios à escola pública compulsória.

  19. Is Neoliberalism Weberian?

    DEFF Research Database (Denmark)

    Ossandón, José

    2014-01-01

    Like a sociological detective of ideas, professor of sociology at the University of Warwick Nicholas Gane (2012, 2014 a, b) has been following the traces of social scientific thought in neoliberalism. The initial clue was given by Michel Foucault who in his Birth of Biopolitics argued that Max...... Weber’s work not only influenced critical theorists such as Adorno and Horkheimer but also one of the main branches within neoliberal thinking, German ordoliberalism. While Gane’s research ended up finding Foucault’s Weber-Ordoliberals connections rather thin, the investigation took him to an even more...... worrying result, namely, Weber’s influence on the work of Ludwig von Mises and his followers in Vienna, including the über neoliberal Friedrich Hayek....

  20. [Women's complaint leadership in the Causa Kleinwächter. A contribution to patient history of the Innsbruck maternity hospital].

    Science.gov (United States)

    Hilber, Marina

    On the basis of the Innsbruck Maternity Clinic this paper deals with the individual and collective worlds of experience of obstetric patients. However, not only the patient's view on the proceedings in this specific medical space is being reconstructed, also the prevailing conventions surrounding the treatment of pregnant, parturient and puerperal patients serving as clinical material in obstetric research and education are critically scrutinised. At the centre of this paper stands Dr. Ludwig Kleinwächter's period of duty, who acted as professor for obstetrics and gynaecology in Innsbruck between 1877 and 1881. During this period numerous conflicts regarding the treatment of patients are documented. Concerned about the good reputation of the Maternity Clinic, the Tyrolean State Committee, as the Clinic's provider, tried to solve the crisis. The existing letters of complaint and protocols do not only give a voice to the women concerned, but also to the medical professions as well as the local political representatives involved.

  1. O zjawisku alienacji w perspektywie rozwoju teorii krytycznej. Feuerbach - Marks - szkoła frankfurcka

    Directory of Open Access Journals (Sweden)

    Malwina Rolka

    2017-01-01

    Full Text Available In my paper I undertake the issue of alienation, that appears at the same sources of modern thought and develops according to the growing consciousness of its conditions and consequences. The first articulation of the phenomenon of alienation we can find in the works of Jean Jacques Rousseau, but its conceptual expression was formulated in the philosophy of Georg Wilhelm Friedrich Hegel. The progress of discourse of alienation in the analyses of Ludwig Feuerbach, Karl Marx and the members of Frankfurt School reveals its essence that depends on the elimination of the personal status of individual. The attempts of overcoming the phenomenon of alienation undertaken by mentioned thinkers leaves the problem unresolved, because of the distinctive feature of all these attempts is mediation the conceptions of human being in limited perspective (concerning individual as mere exemplar of species or as a passive result of an external conditions.

  2. Towards an Anthropology of Infinitude: Badiou and the Political Subject

    Directory of Open Access Journals (Sweden)

    Nina Power

    2006-10-01

    Full Text Available In the English-language reception of Alain Badiou#39;s work, he has often been one-sidedly positioned as a direct heir to the antihumanist projects of Lacan, Althusser and Foucault. Whilst there is much to this claim, this paper argues that the retention of a notion of the #39;political subject#39; in Badiou#39;s work necessarily also depends upon a commitment to a much-underexamined notion of a minimal philosophical anthropology that puts Badiou in a tradition with thinkers such as Ludwig Feuerbach. It is further argued that Badiou#39;s minimal philosophical anthropology is opposed in essence to apparently similar phenomenological projects because it aligns humanity with infinity and not finitude.nbsp;

  3. Semiotic individuation and Ernst Cassirer’s challenge

    DEFF Research Database (Denmark)

    Hoffmeyer, Jesper

    2015-01-01

    . In this understanding, individuation becomes narrowly connected to learning. And since learning necessarily depends on what is already learned, the trajectory of learning-based individuation is necessarily indefinite and dependent on the concrete chance events and steps whereby the process has proceeded. Semiotic...... individuation is a historical process, and this fact explains why systems biology, as established by Ludwig van Bertalanffy, has not been capable of meeting the hope, expressed long ago by Ernst Cassirer, of bridging the mechanicist-vitalist gap in biology. Instead, a semiotic approach is called for. Human...... be defined by its uniqueness as a particular genetic combination, but must be instead be defined by its uniqueness as a temporal outcome of semiotic individuation. Accordingly, this doubletracked character of human semiotic individuation implies that it is cast as just one particular outcome...

  4. Temporality in the Manic Experience: A Selective Review

    Directory of Open Access Journals (Sweden)

    Bruno Trancas

    2012-06-01

    Full Text Available The human experience of time has been the object of study since antiquity, ranging from philosophers to contemporary neuroscience researchers. Some experiences may disturb the relation than Man has with Time, be they general and mundane situations – like a child playing with his toy (Thomas Fuchs – to diseases, such as depressive or manic experiences or the schizophrenic way-of-being-in-theworld. We outline some concepts regarding temporality and shortly after we head on to the disturbance of temporality in the manic experience, both in the world-time (chronometric, explicit and lived time (implicit dimensions, with contributions from several authors, such as Eugène Minkowski, Leston Havens, Ludwig Binswanger, Medard Boss and Thomas Fuchs.

  5. Wissenschaftliche Abhandlungen

    CERN Document Server

    Boltzmann, Ludwig

    2012-01-01

    The Austrian physicist Ludwig Eduard Boltzmann (1844-1906), educated at the University of Vienna, was appointed professor of mathematical physics at the University of Graz in 1869 at the age of only twenty-five. Boltzmann did important work in the fields of statistical mechanics and statistical thermodynamics; for instance, he contributed to the kinetic theory concerned with molecular speeds in gas. Boltzmann also promoted atomic theory, which at the time was still highly controversial. He was a member of the Imperial Austrian Academy of Sciences from 1885 and became a member of the Royal Swedish Academy of Sciences in 1888. This three-volume work, prepared in 1909 by the physicist Fritz Hasenöhrl, one of Boltzmann's students, comprises all his academic publications from 1865 to 1905.

  6. tripleC-Interview mit Kerem Schamberger über Berufsverbote, linke Kommunikationswissenschaft und Kritik an der deutschen Wissenschaftslandschaft

    Directory of Open Access Journals (Sweden)

    Kerem Schamberger

    2017-01-01

    Full Text Available Kerem Schamberger ist ein Doktorand am Institut für Kommunikationswissenschaft und Medienforschung der Ludwig-Maximilians-Universität München. Er ist auch ein linker Aktivist und Mitglied der Deutschen Kommunistischen Partei (DKP. Im Zuge seiner Anstellung wurde auf Basis der bayrischen Gesetzeslage vom Bayrischen Verfassungsschutz geprüft, ob Kerem als verfassungsfeindlich gilt und ihm daher die Anstellung verweigert werden sollte. In der deutschen Mediensoziologie gab es mit Horst Holzer in den 1970er-Jahren einen ähnlichen Fall eines Berufsverbots, das damals durchgesetzt wurde. tripleC hat ein Interview mit Kerem geführt und ihn gebeten, die Hintergründe genauer zu erläutern. Das Interview wurde von Christian Fuchs und Thomas Allmer auf Deutsch geführt und ins Englische übersetzt.

  7. An international campaign of the 19th century to determine the solar parallax. The US Naval expedition to the southern hemisphere 1849-1852

    Science.gov (United States)

    Schrimpf, Andreas

    2014-04-01

    In 1847 Christian Ludwig Gerling, Marburg (Germany), suggested the solar parallax to be determined by measuring the position of Venus close to its inferior conjunction, especially at the stationary points, from observatories on nearly the same meridian but widely differing in latitude. James M. Gilliss, astronomer at the newly founded U.S. Naval Observatory, enthusiastically adopted this idea and procured a grant for the young astronomical community of the United States for an expedition to Chile. There they were to observe several conjunctions of Venus and oppositions of Mars, while the accompanying measurements were to be taken at the US Naval Observatory in Washington D.C. and the Harvard College Observatory at Cambridge, USA. This expedition was supported by A.V. Humboldt, C.F. Gauß, J.F. Encke, S.C. Walker, A.D. Bache, B. Peirce and others. From 1849 to 1852 not only were astronomical, but also meteorological and magnetic observations and measurements recorded, mainly in Santa Lucia close to Santiago, Chile. By comparing these measurements with those taken simultaneously at other observatories around the world the solar parallax could be calculated, although incomplete data from the corresponding northern observatories threatened the project's success. In retrospect this expedition can be recognized as the foundation of the Chilean astronomy. The first director of the new National Astronomical Observatory of Chile was Dr. C.W. Moesta, a Hessian student of Christian Ludwig Gerling's. The exchange of data between German, American and other astronomers during this expedition was well mediated by J.G. Flügel, consul of the United States of America and representative of the Smithsonian Institution in Europe, who altogether played a major role in nurturing the relationship between the growing scientific community in the U.S. and the well established one in Europe at that time.

  8. Findings chest radiograph and CT in mediastinitis: effcacy of CT in patients with delayed diagnosis

    International Nuclear Information System (INIS)

    Son, Eun Ju; Hong, Yong Kook; Choe, Kyu Ok

    1999-01-01

    To analyse the causes the radiologic findings in patients with mediastinitis and to evaluate the efficacy of chest CT scanning in patients with delayed diagnosis. Seventeen patients with histopathologically(n=15) or clinically diagnosed(n=2) mediastinitis were involved in this study. Eleven of the former group underwent surgery, and in four, tube drainage was performed. All underwent chest radiography and CT scanning, and in seven patients, the causes of delayed diagnosis were analysed. The most common cause of mediastinitis was esophageal rupture(n=11). Others were extension from neck abscess to the mediastinum(n=3), complications after a Benthall procedure(n=1), tuberculous lymphadenitis(n=1) and mycotic aneurysm(n=1). Patients with esophageal rupture suffered from underlying diseases such as esophageal cancer(n=2), iatrogenic esophageal rupture(n=2), Boerhaave's syndrome(n=2), and esophagitis(n=1). In patients with neck abscess (n=3), each was secondary to infected cystic hygroma, Ludwig angina, or deep neck infection, respectively. On chest CT, patients with esophageal rupture(n=11) had an abscess in the posterior mediastinum ; nine abscesses extended to the cervical area along the retropharyngeal space, and the patient with Ludwig angina had an abscess involving all compartments of the mediastinum. Among the total of 17 patients, diagnostic delays were found in seven, while five had spontaneous esophageal ruptures and two suffered complications after a Benthall procedure and Tbc lymphadenitis, respectively. The causes of diagnostic delay varied. Among seven patients, pnevmonia was initially diagnosed in two, who were treated ; one had multiorgan failure, and one was suffering from pericardial effusion and lung abscess. In three other patients, chest radiographs initially showed non-specific findings, leading to delayed CT examination. The most common cause of mediastinitis was esophageal rupture, and in these patients, chest radiographs and clinical symptoms

  9. From James Hutton’s «Theory of the Earth» to James Lovelock’s «Gaia Hypothesis»

    Directory of Open Access Journals (Sweden)

    García Cruz, Cándido Manuel

    2007-06-01

    Full Text Available In order to understand to what extent James Hutton (1726-1797 can in fact be considered as one of the first forerunners of the Gaia Hypothesis, his Theory of the Earth is analysed into context
    of the three basic traditions of science: organismic, magical and mechanistic. In the some authors’ opinion, Hutton should have written in his theory the Earth was a superorganism and its proper
    study should be by physiology. These supposed assertions are merely a misinterpretation of the Huttonian philosophy, since were never held by this author. Hutton has nevertheless an holistic view which is closer to the Alfred N. Whitehead's organic mechanicism than the James Lovelock's
    Gaia Hypothesis, being therefore a clear forerunner of Ludwig von Bertalanffy and his System
    General Theory.

    Para comprender en qué medida James Hutton (1726-1797 puede ser considerado en realidad como uno de los primeros precursores de la Hipótesis Gaia, se analiza su Theory of the Earth en el contexto de las tres tradiciones básicas de la ciencia: la organísmica, la mágica y la mecanicista. Para algunos autores, Hutton habría sugerido en su teoría que la tierra era un superorganismo y que la forma más correcta para estudiarla era la fisiología. Estas supuestas afirmaciones son simplemente una interpretación errónea del pensamiento huttoniano, puesto que este autor nunca las hizo. Sin embargo, Hutton posee de hecho una visión holística que está más próxima al mecanicismo orgánico de Alfred N. Whitehead que a la Hipótesis Gaia de James Lovelock, siendo por tanto un claro precursor de Ludwig von Bertalanffy y su Teoría General de Sistemas.

  10. Significados e sentidos da música: uma breve "composição" a partir da psicologia histórico-cultural Significados y sentidos de la música: una breve "composición" a partir de la psicología histórico-cultural Meanings and senses of music: a brief composition from cultural-historical psychology

    Directory of Open Access Journals (Sweden)

    Patrícia Wazlawick

    2007-04-01

    Full Text Available Este artigo discute a construção dos significados e sentidos da música a partir da Psicologia Histórico-Cultural, principalmente com a contribuição de L. S. Vygotski, buscando tecer uma interface com as idéias dos musicoterapeutas noruegueses Even Ruud e Brynjulf Stige, com base na filosofia de Ludwig Wittgenstein. Quando se vivencia a música, não se estabelece relação apenas com a matéria musical em si, mas com toda uma rede de significados construídos no mundo social, em contextos coletivos mais amplos e em contextos singulares. Dessa forma, os significados e sentidos da música são construídos a partir do contexto social, econômico, político, de vivências concretas e da "utilização viva" da música por sujeitos em relação, onde articulam sua dimensão afetiva, desejos e motivações.Este artículo discute la construcción de los significados y sentidos de la música a partir de la Psicología Histórico Cultural, principalmente con la contribución de L. S. Vygotski, buscando formar una conexión con las ideas de los musicoterapeutas noruegos Even Ruud y Brynjulf Stige, en base a la filosofía de Ludwig Wittgenstein. Cuando se vivencia la música, no sólo se relaciona con la materia musical en sí, sino con toda una red de significados construidos en el mundo social, en contextos colectivos más amplios y en contextos singulares. De esa forma, los significados y sentidos de la música son construidos a partir del contexto social, económico, político, de vivencias concretas y de la "utilización viva" de la música por sujetos interrelacionados, donde articulan su dimensión afectiva, deseos y motivaciones.The construction of meanings and senses in music from the point of view of Cultural-Historical Psychology, with special reference to L. S. VygotskI, is discussed. An interface with the ideas of Norwegian music-therapists Even Ruud and Brynjulf Stige, grounded on Ludwig Wittgenstein's philosophy, is highlighted. The

  11. Self-stigma among caregivers of people with mental illness: toward caregivers’ empowerment

    Directory of Open Access Journals (Sweden)

    Girma E

    2014-01-01

    Full Text Available Eshetu Girma,1,2 Anne Maria Möller-Leimkühler,2,3 Sandra Dehning,2,3 Norbert Mueller,2,3 Markos Tesfaye,4 Guenter Froeschl2,5 1Department of Health Education and Behavioral Sciences, Jimma University, Jimma, Ethiopia; 2CIHLMU Center for International Health, Ludwig-Maximilians-Universität, Munich, Germany; 3Department of Psychiatry and Psychotherapy, Ludwig-Maximilians-Universität, Munich, Germany; 4Department of Psychiatry, Jimma University, Jimma, Ethiopia; 5Department of Infectious Diseases and Tropical Medicine, Ludwig-Maximilians-Universität, Munich, Germany Background: In addition to economic and material burdens, caregivers of people with mental illness are exposed to psychosocial challenges. Self-stigma is among the psychological challenges that can be exacerbated by intrinsic and/or extrinsic factors. Caregivers’ self-stigma can negatively influence the patients' treatment and rehabilitation process. The objective of this study was to measure the level and correlates of self-stigma among caregivers of people with mental illness. Methods: An interviewer-administered cross-sectional study was conducted in the Jimma University Specialized Hospital Psychiatry Clinic in Ethiopia on a sample of 422 caregivers. Data were collected by trained nurses working in the clinic using a pretested questionnaire. Multivariate linear regression was performed to identify the correlates of self-stigma among caregivers of people with mental illness. Results: The majority (70.38% of the caregivers were male. On a scale of 0 to 15, with 0 being low and 15 being high, the average self-stigmatizing attitude score was 4.68 (±4.11. A statistically significant difference in mean self-stigma score was found between urban and rural respondents (t=3.95, P<0.05. Self-stigma of caregivers showed significant positive correlation with perceived signs of mental illness (r=0.18, P<0.001, perceived supernatural explanations of mental illness (r=0.26, P<0.001, and

  12. Knowledge transfer within EU-funded marine science research - a viewpoint

    Science.gov (United States)

    Bayliss-Brown, Georgia; Cheallachaín, Cliona Ní

    2016-04-01

    Knowledge transfer, in its most inherent form, can be tracked back to the earliest phase of the Neolithic Revolution, 10,000 years ago, at a time when innovators shared their thoughts on crop cultivation and livestock farming (Bellwood, 2004). Not to be mistaken for science transfer - the export of modern science to non-scientific audiences - it was in the 1960s, that modern knowledge transfer was initiated, when reporting research achievements shifted towards having institutional and political agendas (Lipphardt & Ludwig, 2011). Albeit that the economic contribution of scientific research has been scrutinised for decades; today, there is a pronounced need for the evaluation of its social, cultural and ecological impact. To have impact, it is essential that scientific knowledge is clear and accessible, as well as robust and credible, so that it can be successfully transferred and applied by those identifying solutions for today's societal and environmental challenges. This phenomenon is receiving growing academic interest, where publications including "knowledge transfer" in the title have increased near exponentially for 60 years. Furthermore, we are seeing a definite shift towards embedding a mission of knowledge transfer in Public Research Organisations. This new approach is rewarding researchers whom deliver on all three institutional missions: teaching, research and knowledge transfer. In addition, the European Commission (2008) recommends that "knowledge transfer between universities and industry is made a permanent political and operational priority" and that "sufficient resources and incentives [be] available to public research organisations and their staff to engage in knowledge transfer activities". It is also anticipated that funding agencies will soon make pathways-to-impact statements, also known as knowledge transfer plans, a mandatory requirement of all project proposals. AquaTT is a leader in scientific knowledge management, including knowledge

  13. Self-knowledge in the process of interpreting philosophical texts

    Directory of Open Access Journals (Sweden)

    A. V. Kulik

    2016-08-01

    Full Text Available Modern philosophical researches pay attention to various aspects of self-knowledge investigation. For instance, there are works on historical concepts of self-knowledge (e.g. ones by C. Moore, or articles about the place of self-knowledge in the phenomenon of rationality (e.g. ones by J. Roessler, or articles about epistemological lacks of self-knowledge (e.g. ones by J. Fernández. However, our paper is about the aspect that is not in the researchers’ centre of attention. Our study shows that practicing of book reading can be a source of information not only about the content of the books, but also about their readers. We investigate a phenomenon of incompatible interpretations, Ludwig Wittgenstein’s ideas about understanding his texts, Merab Mamardashvili’s concept of ‘novel as a machine’, Ludwig Feuerbach’s theory of specifics of human cognition, and Philosophical Hermeneutics thinkers’ concepts about problems of understanding. The purpose of our paper is to describe possibilities of getting self-knowledge by analyzing the information about the results of philosophical texts reading. The research holds that these results give information about the content of the text as well as a reader’s ideas. A reader can use word forms from the texts to express his own implicit thoughts. Philosophical texts are the most effective tool for doing that because their content and ways of text organization stimulate such an activity. We illustrate these statements by examples from history of philosophy. For instance, we investigate the creation of the theory on the genealogy of morality by Friedrich Nietzsche. Analyzing phrases, which were important for him in the text, a person can estimate his own ideas. If one uses this theoretical model for getting self-knowledge he takes a new source of information about his own implicit ideas. The interpretation of this information will be effective. As a result of analyzing of Friedrich Schleiermacher

  14. The predictive value of somatic and cognitive depressive symptoms for cytokine changes in patients with major depression

    Directory of Open Access Journals (Sweden)

    Dannehl K

    2014-06-01

    Full Text Available Katharina Dannehl,1 Winfried Rief,1 Markus J Schwarz,2 Annika Hennings,1 Sabine Riemer,1 Verena Selberdinger,3 Theresa Stapf,3 Frank Euteneuer11Division of Clinical Psychology and Psychotherapy, Philipps Universität Marburg, Marburg, Germany; 2Institute for Laboratory Medicine, Ludwig-Maximilian Universität, Munich, Germany; 3Department of Psychiatry, Ludwig-Maximilian Universität, Munich, GermanyContext: Elevated concentrations of proinflammatory cytokines have been hypothesized as an important factor in the pathophysiology of depression. Depression itself is considered to be a heterogeneous disorder. Current findings suggest that “cognitive” and “somatic” symptom dimensions are related to immune function in different ways. So far, little research has been done on the longitudinal aspects of inflammation in patients with major depression, especially with respect to different symptom dimensions of depression. Therefore, we investigated which aspects of depression may predict changes in tumor necrosis factor-alpha (TNF-alpha and interleukin (IL-6 over 4 weeks. Methods: Forty-one patients with major depression diagnosed according to the Diagnostic and Statistical Manual of Mental Disorders, fourth edition (DSM-IV, and 45 healthy controls were enrolled. Serum measurements of TNF-alpha and IL-6 were conducted at baseline and 4 weeks later. Psychometric measures included the assessment of cognitive-affective depressive symptoms and somatic symptoms during the last 7 days as well as somatic symptoms during the last 2 years. Results: Patients with depression showed increased levels of TNF-alpha (P<0.05 compared to healthy controls. Hierarchical regression analyses indicated that neither depressive nor somatic symptoms predict changes in proinflammatory cytokines in the whole sample of depressed patients. Moderation analyses and subsequent sex-stratified regression analyses indicated that higher somatoform symptoms during the last 2 years

  15. Reviews in Modern Astronomy 28: From the First Quasars to Life-Bearing Planets - From Accretion Physics to Astrobiology

    Science.gov (United States)

    Berlepsch, Regina v.

    2016-07-01

    The current issue of AN is Volume 28 of the Reviews in Modern Astronomy and presents the Karl Schwarzschild Award Lecture, the Ludwig Bierman n Award Lecture and the Doctoral Thesis Award Lecture given at the 88th Annual International Scientific Meeting of the Astronomische Gesellschaft held in Kiel, Germany, September 14-18, 2015. It was the fifth time that Kiel hosted a meeting of the AG, the first one was in 1887. In 2015 the fall meeting was a part of the celebrations of the 350th anniversary of the Christiana Albertina University Kiel in 1665. For astronomers around the globe, the astrophysical group is well known for the Kieler Schule and its fundamental contributions to the physics of stellar atmospheres. Based on the work by Albrecht Unsöld during his tenure of 41 years as active researcher and lecturer (and many more after becoming emeritus), the quantitative analysis of stellar atmospheres and the reliable determination of chemical abundances is nowadays a cornerstone of modern astrophysics. Even more, it is of ground-laying importance for the whole field, from the characterization of exoplanets and their host stars to the properties of galaxies at cosmic dawn. The meeting was guided by the theme "From the First Quasars to Life-Bearing Planets -- From Accretion Physics to Astrobiology". The meeting was attended by almost 300 participants from around the world. The Karl Schwarzschild Medal 2015 of the Astronomische Gesellschaft was awarded to Professor Immo Appenzeller, Heidelberg. His lecture with the title "Astronomical technology -- the past and the future" opened the meeting. The talk presented by the Ludwig Biermann Award winner 2015, Dr. Ivan Minchev, Potsdam, dealt with the topic "Constraining the Milky Way assembly history with Galactic Archaeology". The Doctoral Thesis Award 2015 was awarded to Dr. Cornelia Müller (Würzburg). In her lecture she discussed the subject "Multiwavelength and parsec-scale properties of extragalactic Jets". The AG

  16. The nuclear phase-out and its consequences; Der Atomausstieg und seine Folgen

    Energy Technology Data Exchange (ETDEWEB)

    Ludwigs, Markus

    2016-07-01

    As a lesson from the Fukushima nuclear disaster, a radical change has taken place in climate and energy policy in Germany since 2011. This is characterized by the phase-out of the nuclear energy, which is fixed by the 13th Atomic Enforcement Act, by the end of 2022. This entails a multitude of complex legal questions and subsequent problems. The latest decisions are the forthcoming decisions of the BVerfG on the constitutional consistency of the nuclear phase-out law and nuclear fuel tax, Vattenfall's much discussed arbitration award before the ICSID arbitration court, and controversial legal questions both in the context of the decommissioning and dismantling of nuclear power plants and the disposal of highly radioactive waste. In addition, the moral-ethical evaluation of the nuclear phase-out and the power turn-around is the focus of the interdisciplinary approach. The problem clusters are analyzed by the contributions of the anthology. He documents a conference organized by Professor Dr. Markus Ludwig, which took place on April 8, 2016, at the University of Wuerzburg, within the framework of a project funded by the Fritz Thyssen Stiftung (''The Law of the Energy Transition''). [German] Als Lehre aus der Atomkatastrophe von Fukushima ist in Deutschland seit 2011 ein radikaler Wandel in der Klima- und Energiepolitik erfolgt. Praegend hierfuer ist der durch die 13. Atomgesetznovelle fixierte Ausstieg aus der Kernenergie bis Ende 2022. Damit verbunden ist eine Vielzahl komplexer Rechtsfragen und Folgeprobleme. Aktuelle Schlaglichter bilden die anstehenden Entscheidungen des BVerfG zur Verfassungskonformitaet von Atomausstiegsgesetz und Kernbrennstoffsteuer, die vieldiskutierte Schiedsklage von Vattenfall vor dem ICSID-Schiedsgericht sowie die kontroversen Rechtsfragen sowohl im Kontext der Stilllegung und des Rueckbaus von Kernkraftwerken als auch hinsichtlich der Endlagerung hochradioaktiver Abfaelle. Daneben steht in interdisziplinaerer

  17. Findings chest radiograph and CT in mediastinitis: effcacy of CT in patients with delayed diagnosis

    Energy Technology Data Exchange (ETDEWEB)

    Son, Eun Ju; Hong, Yong Kook; Choe, Kyu Ok [Yonsei Univ. College of Medicine, Seoul (Korea, Republic of)

    1999-01-01

    To analyse the causes the radiologic findings in patients with mediastinitis and to evaluate the efficacy of chest CT scanning in patients with delayed diagnosis. Seventeen patients with histopathologically(n=15) or clinically diagnosed(n=2) mediastinitis were involved in this study. Eleven of the former group underwent surgery, and in four, tube drainage was performed. All underwent chest radiography and CT scanning, and in seven patients, the causes of delayed diagnosis were analysed. The most common cause of mediastinitis was esophageal rupture(n=11). Others were extension from neck abscess to the mediastinum(n=3), complications after a Benthall procedure(n=1), tuberculous lymphadenitis(n=1) and mycotic aneurysm(n=1). Patients with esophageal rupture suffered from underlying diseases such as esophageal cancer(n=2), iatrogenic esophageal rupture(n=2), Boerhaave's syndrome(n=2), and esophagitis(n=1). In patients with neck abscess (n=3), each was secondary to infected cystic hygroma, Ludwig angina, or deep neck infection, respectively. On chest CT, patients with esophageal rupture(n=11) had an abscess in the posterior mediastinum ; nine abscesses extended to the cervical area along the retropharyngeal space, and the patient with Ludwig angina had an abscess involving all compartments of the mediastinum. Among the total of 17 patients, diagnostic delays were found in seven, while five had spontaneous esophageal ruptures and two suffered complications after a Benthall procedure and Tbc lymphadenitis, respectively. The causes of diagnostic delay varied. Among seven patients, pnevmonia was initially diagnosed in two, who were treated ; one had multiorgan failure, and one was suffering from pericardial effusion and lung abscess. In three other patients, chest radiographs initially showed non-specific findings, leading to delayed CT examination. The most common cause of mediastinitis was esophageal rupture, and in these patients, chest radiographs and clinical

  18. Interview with Peter Jenni

    CERN Multimedia

    PH Newsletter

    2013-01-01

    Peter Jenni, former spokesperson of the ATLAS Collaboration, discusses the challenges and satisfactions from his long-standing career in high-energy physics in this month’s PH Newsletter.   Peter Jenni. Following a long career at CERN that dates back to 1970 (ranging from Summer Student to Fellow and to Staff), Peter Jenni recently retired after about 40 years marked by exciting discoveries (from the first two-photon production of eta-prime at SPEAR to the Higgs boson at the LHC). Peter was involved in the LHC from its very beginnings and was spokesperson of the ATLAS Collaboration until February 2009. Peter Jenni will continue working with ATLAS as a guest scientist with the Albert-Ludwigs-University Freiburg, and when he's not travelling he still spends most of his time in his office in Building 40, where he met with interviewer Panos Charitos. Panos Charitos: When did you first arrive to CERN? Peter Jenni: I first came to CERN as a Summer Student in ...

  19. WITTGENSTEIN AND PHILOSOPHICAL SPIRITUALITY IN THE LIGHT OF THE LECTURE ON ETHICS

    Directory of Open Access Journals (Sweden)

    Tommaso Manzon

    2016-03-01

    Full Text Available Lo scopo di questo paper è quello di sviluppare una lettura e un’interpretazione di uno degli scritti “minori” di Ludwig Wittgenstein, la Conferenza sull’Etica. La mia comprensione della Conferenza è inspirata principalmente dall’interpretazione della filosofia di Wittgenstein sviluppata da Pierre Hadot e, di conseguenza, la mia tesi consisterà nel dimostrare che seguendo Hadot la Conferenza sull’Etica può essere vista come un ‘Esercizio Spirituale’. Pertanto sostengo che la finalità principale di questo scritto va vista nel tentativo di cambiare la nostra attitudine verso il mondo, e dunque la nostra disposizione etica verso di esso. Ritengo inoltre che questo non sia solo lo scopo di ogni Esercizio Spirituale, bensì in generale quello dell’attività del filosofo austriaco, ossia, la volontà di coinvolgere i propri destinatari provocando in loro una riflessione e possibilmente un cambiamento in merito al proprio modo di vivere, e a tutta la sfera che va sotto il nome di “Etica”.

  20. Von Kármán between Aachen and Pasadena

    Science.gov (United States)

    Krause, Egon; Kalkmann, Ulrich

    2013-05-01

    In the Introduction the reader is referred back to the academic ceremonials held after Theodore von Kármán's death in Aachen in May 1963. His work as the first director of the Aerodynamisches Institut (Institute of Aerodynamics) of the RWTH Aachen University of Technology from 1913 on and his initiative to re-establish international cooperation after World War I, resulting in the International Union of Theoretical and Applied Mechanics (IUTAM), are commented on. The following chapter describes von Kármán's relation to his former teacher Ludwig Prandtl. Some of von Kármán's scientific contributions during his time in Aachen are briefly reviewed. Thereafter, his first contacts to the California Institute of Technology are covered. Finally, the scientific and political circumstances, which led to von Kármán's decision to leave Germany in the early thirties, are elucidated in some detail. The English translation of the titles of the Aachen papers is given in Appendix I.

  1. Jogos de linguagem/jogos de verdade: de Wittgenstein a Foucault

    Directory of Open Access Journals (Sweden)

    Elza Ibrahim

    2014-01-01

    Full Text Available El artículo trae a discusión la cuestión de la constitución del sujeto a través de los juegos de verdad y de los juegos de lenguaje, problematizados, respectivamente, por Michel Foucault y Ludwig Wittgenstein, teniendo como hilo conductor las implica - ciones del lenguaje en las prácticas que realizadas en un hospital psiquiátrico-penal con pacientes inimputables. Para ello, presentamos la visión objetivista de realidad y del lenguaje figurativo, en lugar del punto de vista constructivista de la realidad y del lenguaje pragmático. De acuerdo con este último punto de vista, la realidad es producida por el lenguaje a través de juegos de lenguaje, históricamente contextua - lizadas. Por lo tanto, estaríamos hablando de sujetos únicos, y no del sujeto trascen - dental. En este contexto, traemos a la discusión la noción de verdad problematizada por Foucault como un campo de potencial. Para él, es tan sólo en la contingencia de la historia que se constituye el sujeto: como el lenguaje, él es producto de múltiples prácticas sociales.

  2. Fluocinolone acetonide and its potential in the treatment of chronic diabetic macular edema

    Directory of Open Access Journals (Sweden)

    Haritoglou C

    2013-03-01

    Full Text Available Christos Haritoglou, Aljoscha S Neubauer, Marcus KerntDepartment of Ophthalmology, Ludwig-Maximilians-University, Munich, GermanyAbstract: Diabetic macular edema (DME is a potentially sight-threatening disease that predominantly affects patients with type 2 diabetes. The pathogenesis is complex, with many contributing factors involved. In addition to overexpression of vascular endothelial growth factor in the diabetic eye, there is an inflammatory pathway that contributes to the breakdown of the blood-retina barrier and nonperfusion. In addition to vascular endothelial growth factor inhibitors, clinical and experimental investigations underline the great potential of steroids in the treatment of DME. Fluocinolone acetonide is currently the only corticosteroid approved for the treatment of DME in Europe. It is manufactured as an intravitreal insert, releasing fluocinolone acetonide at a rate of 0.2 µg per day. Phase III clinical studies have demonstrated that the beneficial effect of the fluocinolone acetonide insert lasts up to 3 years. Improvement in visual acuity was especially remarkable in patients with a prolonged duration of DME of at least 3 years at the initiation of therapy. Cataract formation occurs in nearly all phakic eyes treated, and needs to be considered when the indication for treatment is made. Given the efficacy versus potential complications of the insert, fluocinolone acetonide represents a promising second-line treatment option in patients with DME. Fluocinolone appears to be especially beneficial for patients whose options for visual recovery have seemed limited up until now.Keywords: diabetic macular edema, fluocinolone acetonide

  3. The effect of physical activity on sleep quality, well-being, and affect in academic stress periods

    Directory of Open Access Journals (Sweden)

    Wunsch K

    2017-04-01

    Full Text Available Kathrin Wunsch, Nadine Kasten, Reinhard Fuchs Department of Sport Science, Sport Psychology Unit, Albert-Ludwigs University Freiburg, Freiburg im Breisgau, Germany Abstract: The stress-buffering hypothesis postulates that physical activity and exercise can buffer the negative effects of (academic stress on health. It still remains an open question whether students, who regularly engage in physical activity and exercise within their academic examination period, can successfully diminish these negative effects. Sixty-four subjects participated in this study and completed a total of five surveys, with T1 at the end of the semester break (baseline and T2–T5 being presented every Friday in the last 4 weeks of the semester (examination period. They were asked to answer questions about their activity level, sleep quality, well-being and affect. Hierarchical linear models showed significant dependencies on time for all dependent measures. The expansion of the model for exercise also showed significant main effects of this predictor on well-being and positive affect (PA and negative affect. Moreover, significant interactions with time for sleep quality and PA were found. Results suggest that physical activity and exercise in the academic examination period may be able to buffer the negative effects of stress on health-related outcomes. Therefore, activity levels should be maintained in times of high stress to prevent negative effects on sleep, well-being and affect in students. Keywords: examination stress, exercise, stress-buffering hypothesis

  4. Wokół własności. Próba uporządkowania stanowisk w filozofii politycznej (PRIVATE PROPERTY. AN ATTEMPT AT CLASSIFICATION THE KEY POSITIONS IN POLITICAL PHILOSOPHY

    Directory of Open Access Journals (Sweden)

    Dariusz Juruś

    2007-06-01

    Full Text Available In the paper the author proposes a new model of political spectrum. Instead - as so far - arranging political philosophies in two or four dimensional diagrams (from the left to the right, from the top to the bottom he suggests a form of spiral, where political philosophies evolve naturally from amoralistic anarchism to communism. He also puts some names of philosophers who represent respective political views. Thus we start from amoralistic anarchism by Max Stirner, then we have moralistic anarchism by Murray N. Rothbard, then moralistic minarchism by Robert Nozick, which in turn evolves into utilitarian minarchism by Ludwig von Mises, then utilitarian liberalism by Friedrich A. von Hayek, socialist liberalism by John Rawls and socialism leading to communism by Karl Marx. In this model one organizes political views not as usually around the concept of freedom (personal and economic, but around the concept of private property. Therefore we are able to include in this model anarchism, which is usually ignored, as a non-political view.

  5. Acoustic and social design of schools-ways to improve the school listening environment

    Science.gov (United States)

    Hagen, Mechthild

    2005-04-01

    Results of noise research indicate that communication, and as a result, teaching, learning and the social atmosphere are impeded by noise in schools. The development of strategies to reduce noise levels has often not been effective. A more promising approach seems to be to pro-actively support the ability to listen and to understand. The presentation describes the approach to an acoustic and social school design developed and explored within the project ``GanzOhrSein'' by the Education Department of the Ludwig-Maximilians-University of Munich. The scope includes an analysis of the current ``school soundscape,'' an introduction to the concept of the project to improve individual listening abilities and the conditions for listening, as well as practical examples and relevant research results. We conclude that an acoustic school design should combine acoustic changes in classrooms with educational activities to support listening at schools and thus contribute to improving individual learning conditions and to reducing stress on both pupils and teachers.

  6. Notes on the origins of Epilepsia and the International League Against Epilepsy.

    Science.gov (United States)

    Shorvon, Simon D; Weiss, Giselle; Goodkin, Howard P

    2009-03-01

    The recent discovery of archival material has shed interesting light on the origins of Epilepsia and also the International League Against Epilepsy (ILAE). The idea of an international journal devoted to epilepsy seems first to have arisen from talks between Dr. L. J. J. Muskens and Dr. W. Aldren Turner in 1905. A protracted series of subsequent letters between Muskens and a Haarlem publisher show how the idea slowly took shape. The committee of patronage, editorial board, and editorial assistants was probably first approached at the First International Congress of Psychiatry, Neurology, Psychology, and Nursing of the Insane, held in Amsterdam in 1907. At this meeting, the concept of an international organization to fight epilepsy (to become the ILAE) was also first proposed in public, again by Muskens. The concept of the ILAE was clearly modeled on another international organization-the International Commission for the Study of the Causes of Mental Diseases and Their Prophylaxis. This Commission had been first publicly proposed in 1906 by Ludwig Frank, at the Second International Congress for the Care and Treatment of the Insane. The proposed Commission and ILAE shared many features, aims, and personnel. Despite an auspicious start, the International Commission was prevented by personal and political differences from ever actually coming into being. However, the first issue of Epilepsia appeared in March 1909 and the ILAE was inaugurated in August 1909; and both have flourished and celebrate their centenaries this year.

  7. On the Possibility of Assigning Probabilities to Singular Cases, or: Probability Is Subjective Too!

    Directory of Open Access Journals (Sweden)

    Mark R. Crovelli

    2009-06-01

    Full Text Available Both Ludwig von Mises and Richard von Mises claimed that numerical probability could not be legitimately applied to singular cases. This paper challenges this aspect of the von Mises brothers’ theory of probability. It is argued that their denial that numerical probability could be applied to singular cases was based solely upon Richard von Mises’ exceptionally restrictive definition of probability. This paper challenges Richard von Mises’ definition of probability by arguing that the definition of probability necessarily depends upon whether the world is governed by time-invariant causal laws. It is argued that if the world is governed by time-invariant causal laws, a subjective definition of probability must be adopted. It is further argued that both the nature of human action and the relative frequency method for calculating numerical probabilities both presuppose that the world is indeed governed by time-invariant causal laws. It is finally argued that the subjective definition of probability undercuts the von Mises claim that numerical probability cannot legitimately be applied to singular, non-replicable cases.

  8. Delayed gastrointestinal recovery after abdominal operation – role of alvimopan

    Directory of Open Access Journals (Sweden)

    Berger NG

    2015-08-01

    Full Text Available Nicholas G Berger, Timothy J Ridolfi, Kirk A LudwigDivision of Colorectal Surgery, Department of Surgery, Medical College of Wisconsin, Milwaukee, Wisconsin USAAbstract: Postoperative Ileus (POI, which occurs after surgical manipulation of the bowel during abdominal operations, is associated with prolonged hospital stay, increasing medical costs, and delayed advancement of enteral diet, which contributes to a significant economic burden on the healthcare system. The use of accelerated care pathways has shown to positively impact gut function, but inevitable postoperative opioid use contributes to POI. Alvimopan is a peripherally acting µ-opioid receptor antagonist designed to mitigate antimotility effects of opioids. In our review, we examined ten trials on alvimopan's use after abdominal operations. Several of the earlier studies on patients undergoing bowel resection showed correlations between the study group and GI recovery as defined by passage of flatus, first bowel movement, and time to readiness for discharge. Data in patients undergoing total abdominal hysterectomy showed similarly decreased GI recovery time. Additionally, data within the past few years shows alvimopan is associated with more rapid GI recovery time in patients undergoing radical cystectomy. Based on our review, use of alvimopan remains a safe and potentially cost-effective means of reducing POI in patients following open GI surgery, radical cystectomy, and total abdominal hysterectomy, and should be employed following these abdominal operations.Keywords: postoperative ileus, alvimopan, ileus, bowel resection, return of bowel function

  9. Activation measurements for fast neutrons. Part D. Evaluation of cosmic-ray-induced 63Ni background in copper

    International Nuclear Information System (INIS)

    Ruehm, Werner; Rugel, Georg; Faestermann, Thomas

    2005-01-01

    As a result of a joint collaboration between the University of Utah, LLNL, the Technical University Munich and the Ludwig Maximilians University Munich, it became possible to determine A-bomb induced 63 Ni in pure copper samples from Hiroshima beyond a ground range of 1,000 m (see Chapter 9, Part B). The low 63 Ni activities induced in copper samples due to neutrons from the A-bomb explosion at large distance require, however, a careful discussion of the fraction of 63 Ni produced in these samples due to cosmic radiation. In this section, an analysis of the production of 63 Ni in copper samples due to cosmic radiation is performed. Production due to neutrons, protons, stopped muons, and photonuclear reactions is discussed. It is obvious from Figure 1 (Pfennig et al. 1995) that a variety of reactions induced by neutrons, protons, muons and photons can contribute to the production of 63 Ni in copper. The most important of these processes will be discussed here. Since the cross-sections for the production of 63 Ni in copper samples due to fast and stopped muons were not known, they were determined experimentally. (J.P.N.)

  10. Howard Brenner's Legacy for Biological Transport Processes

    Science.gov (United States)

    Nitsche, Johannes

    2014-11-01

    This talk discusses the manner in which Howard Brenner's theoretical contributions have had, and long will have, strong and direct impact on the understanding of transport processes occurring in biological systems. His early work on low Reynolds number resistance/mobility coefficients of arbitrarily shaped particles, and particles near walls and in pores, is an essential component of models of hindered diffusion through many types of membranes and tissues, and convective transport in microfluidic diagnostic systems. His seminal contributions to macrotransport (coarse-graining, homogenization) theory presaged the growing discipline of multiscale modeling. For biological systems they represent the key to infusing diffusion models of a wide variety of tissues with a sound basis in their microscopic structure and properties, often over a hierarchy of scales. Both scientific currents are illustrated within the concrete context of diffusion models of drug/chemical diffusion through the skin. This area of theory, which is key to transdermal drug development and risk assessment of chemical exposure, has benefitted very directly from Brenner's contributions. In this as in other areas, Brenner's physicochemical insight, mathematical virtuosity, drive for fully justified analysis free of ad hoc assumptions, quest for generality, and impeccable exposition, have consistently elevated the level of theoretical understanding and presentation. We close with anecdotes showing how his personal qualities and warmth helped to impart high standards of rigor to generations of grateful research students. Authors are Johannes M. Nitsche, Ludwig C. Nitsche and Gerald B. Kasting.

  11. From ‘Nerve Fiber Regeneration’ to ‘Functional Changes’ in the Human Brain – On the Paradigm-Shifting Work of the Experimental Physiologist Albrecht Bethe (1872-1954 in Frankfurt am Main

    Directory of Open Access Journals (Sweden)

    Frank W Stahnisch

    2016-02-01

    Full Text Available Until the beginning 1930s the traditional dogma that the human central nervous system did not possess any abilities to adapt functionally to degenerative processes and external injuries loomed large in the field of the brain sciences (Hirnforschung. Cutting-edge neuroanatomists, such as the luminary Wilhelm Waldeyer (1836–1921 in Germany or the Nobel Prize laureate Santiago Ramón y Cajal (1852–1934 in Spain, debated any regenerative and thus plastic properties in the human brain. A renewed interest arose in the scientific community to investigate the pathologies and the healing processes in the human central nervous system after the return of the high number of brain injured war veterans from the fronts during and after the First World War (1914–1918. A leading research center in this area was the Institute for the Scientific Study of the Effects of Brain Injuries, which the neurologist Ludwig Edinger (1855–1918 had founded shortly before the war. This article specifically deals with the physiological research on nerve fiber plasticity by Albrecht Bethe (1872–1954 at the respective institute of the University of Frankfurt am Main. Bethe conducted here his paradigmatic experimental studies on the pathophysiological and clinical phenomena of peripheral and central nervous system regeneration.

  12. [Contribution of Berlin clinics and especially the Charité to the development of modern anesthesia in Germany].

    Science.gov (United States)

    Wauer, H J; Kühne, H; Kox, W J

    2000-01-01

    Soon after announcement of the first American ether anesthesias in 1846 one started to anesthetize with ether in Europe. The first ether anesthesia in Germany took place on January 24th, 1947, and was given by Johann Ferdinand Heyfelder in Erlangen. Two weeks later the first ether anesthesia in Berlin was given on February 6th, 1847, by the orthopaedic surgeon Heimann-Wolff Berend. On February 12th, 1847, the surgeon Johann Friedrich Dieffenbach used ether to anesthetize a patient in the Berlin university hospital. Still in 1847 he published his book "The Ether against Pain" which used to be the standard textbook of anesthesia in Germany for many years to come. On February 15th, 1847, Johann Christian Jüngken operated his first patient under ether anesthesia in the surgical department of the Charité hospital assisted by Rudolf Virchow. Since then several famous Berlin surgeons influenced the development of modern anesthesia until the middle of the 20th century. The nitrous oxide bottle was introduced into practice by the Barth company in cooperation with the dentist Carl Sauer and Kurt Schimmelbusch introduced his mask for ether anesthesia. Carl Ludwig Schleich reported at the German congress of surgery in 1894 about his first experience with infiltration anesthesia. Spinal anesthesia developed by August Bier in Kiel was improved during his time in Berlin.

  13. Classifications of patterned hair loss: a review

    Directory of Open Access Journals (Sweden)

    Mrinal Gupta

    2016-01-01

    Full Text Available Patterned hair loss is the most common cause of hair loss seen in both the sexes after puberty. Numerous classification systems have been proposed by various researchers for grading purposes. These systems vary from the simpler systems based on recession of the hairline to the more advanced multifactorial systems based on the morphological and dynamic parameters that affect the scalp and the hair itself. Most of these preexisting systems have certain limitations. Currently, the Hamilton-Norwood classification system for males and the Ludwig system for females are most commonly used to describe patterns of hair loss. In this article, we review the various classification systems for patterned hair loss in both the sexes. Relevant articles were identified through searches of MEDLINE and EMBASE. Search terms included but were not limited to androgenic alopecia classification, patterned hair loss classification, male pattern baldness classification, and female pattern hair loss classification. Further publications were identified from the reference lists of the reviewed articles.

  14. Novel Approach to Treating Androgenetic Alopecia in Females With Photobiomodulation (Low-Level Laser Therapy).

    Science.gov (United States)

    Friedman, Shelly; Schnoor, Patricia

    2017-06-01

    Photobiomodulation, also referred to as low-level laser therapy (LLLT), has been studied and used for (among other diseases) the promotion of hair regrowth. A clinical study was developed to define the physiologic effects that occur when the human hair follicle and surrounding tissue structures are exposed to laser light using a novel device that is fitted with an array of laser diode sources operating at 650 nm and placed inside a sports cap to promote discretion while in use. The study demonstrates that low-level laser treatment of the scalp every other day for 17 weeks using the HANDI-DOME LASER device is a safe and effective treatment for androgenetic alopecia in healthy females between the ages of 18 to 60 with Fitzpatrick skin Types I to IV and Ludwig-Savin Baldness Scale I-2 to II-2 baldness patterns. Subjects receiving LLLT at 650 nm achieved a 51% increase in hair counts as compared with sham-treated control patients in this multicenter randomized controlled trial. These results suggest that the emerging technology of low-level laser therapy may play a potentially significant role in health care providers' armamentarium for the disease androgenic alopecia.

  15. [The motivation to become a medical doctor - doctoral students in a formal academic study program compared with those pursuing their doctorate independently].

    Science.gov (United States)

    Pfeiffer, M; Dimitriadis, K; Holzer, M; Reincke, M; Fischer, M R

    2011-04-01

    Weight and quality of medical doctoral theses have been discussed in Germany for years. Doctoral study programs in various graduate schools offer opportunities to improve quality of medical doctoral theses. The purpose of this study was to demonstrate distinctions and differences concerning motivation, choice of subject and the dissertation process between doctoral candidates completing the doctoral seminar for doctoral students in the Ludwig-Maximilians-University (LMU) Munich and doctoral candidates doing their doctorate individually. All 4000 medical students of the LMU obtained an online-questionnaire which was completed by 767 students (19 % response rate). The theoretical framework of this study was based upon the Self-Determination-Theory by Deci and Ryan. Doctoral candidates completing the doctoral study program were more intrinsically motivated than doctoral candidates doing their doctorate individually; no difference was found in their extrinsic motivation. In regard to choice of subject and dissertation process the doctoral students in the seminar were distinguished from the individual group by having chosen a more challenging project. They anticipated a demanding dissertation process including conference participation, publishing of papers, etc. Intrinsic motivation correlates positively with choosing a challenging project and a demanding dissertation process. High intrinsic motivation seems to be very important for autonomous scholarly practice. Our results suggest that doctoral study programs have a positive impact on intrinsic motivation and interest in research. © Georg Thieme Verlag KG Stuttgart · New York.

  16. A Study on the Compatibility of 3-D Seismic Velocity Structures with Gravity Data of Taiwan

    Directory of Open Access Journals (Sweden)

    Horng-Yuan Yen Hsien-Hsiang Hsieh

    2010-01-01

    Full Text Available The Bouguer anomaly of Taiwan has been revised in this study based on more accurate terrain data provided by the Taiwanese Digital Terrain Model compiled by the Taiwan Forestry Bureau. Three seismic velocity models, those determined by Rau and Wu (1995, Kim et al. (2005, and Wu et al. (2007 respectively, were selected for our study. We converted their velocity models to density models using the relationship between P-wave velocity and rock density proposed by Ludwig et al. (1970 and Barton (1986, and then calculated their corresponding gravity anomalies. According to the correlation coefficient between the Bouguer anomalies calculated from the velocity models and the revised Bouguer anomalies, the Kim et al. model was more compatible with gravity data than the other two velocity models. The differences between the revised gravity anomaly and the calculated gravity anomalies trend toward positive values at elevations higher than 2000 m. This indicates that the velocities at the shallower depths beneath the mountainous area of the three models are overdetermined, i.e., higher than the real velocities. This ratiocination implies that the crustal thickness beneath the Central Range is less than 55 km which was obtained from the velocity models.

  17. An improved molecular dynamics algorithm to study thermodiffusion in binary hydrocarbon mixtures

    Science.gov (United States)

    Antoun, Sylvie; Saghir, M. Ziad; Srinivasan, Seshasai

    2018-03-01

    In multicomponent liquid mixtures, the diffusion flow of chemical species can be induced by temperature gradients, which leads to a separation of the constituent components. This cross effect between temperature and concentration is known as thermodiffusion or the Ludwig-Soret effect. The performance of boundary driven non-equilibrium molecular dynamics along with the enhanced heat exchange (eHEX) algorithm was studied by assessing the thermodiffusion process in n-pentane/n-decane (nC5-nC10) binary mixtures. The eHEX algorithm consists of an extended version of the HEX algorithm with an improved energy conservation property. In addition to this, the transferable potentials for phase equilibria-united atom force field were employed in all molecular dynamics (MD) simulations to precisely model the molecular interactions in the fluid. The Soret coefficients of the n-pentane/n-decane (nC5-nC10) mixture for three different compositions (at 300.15 K and 0.1 MPa) were calculated and compared with the experimental data and other MD results available in the literature. Results of our newly employed MD algorithm showed great agreement with experimental data and a better accuracy compared to other MD procedures.

  18. A historical-archaeological investigation of an Anglo-Boer War British outpost in the Kruger National Park

    Directory of Open Access Journals (Sweden)

    Anton C. Van Vollenhoven

    1998-08-01

    Full Text Available During the Anglo-Boer War (1899-1902 a voluntary British military unit called Steinaecker's Horse, operated in the Lowveld and Swaziland. The commander of the unit, colonel Ludwig von Steinaecker, was an important historical figure in this area. The unit established a number of outposts in an area today known as the Kruger National Park. One of these outposts was archaeologically investigated in order to recover any remains that may be associated with this unit and to form some idea of their lifestyle. Although no historical information on this particular outpost was found, the archaeological excavations revealed some interesting evidence. The disturbance of the site and the number of visible cultural material, indicated that it was used in recent times. The large refuse middens show that a reasonably large number of people occupied the site. Most of the artifacts found can be linked to the diet and articles of everyday use of the inhabitants. The conclusion is that the site was probably occupied by both a garrison of the Steinaecker's Horse military unit and some troops of the Native Police unit. Based on the distribution of different types of artifacts on the site a social differ- entiation between the members of these two units is assumed.

  19. Fuel cell propulsion for urban duty vehicles: Bavarian fuel cell bus project

    International Nuclear Information System (INIS)

    Wurster, R.; Altmann, M.; Sillat, D.; Kalk, K. W.; Hammerschmidt, A.; Stuehler, W.; Holl, E.

    1998-01-01

    Following a feasibility study and a detailed specification phase, the realization of a fuel cell city bus prototype was started in autumn 1996. The project is a joint development effort of Siemens, MAN and Linde, which receives a 50 % funding by the Bavarian State Ministry for Economic Affairs, Transport and Technology (BStMWVT) in the context of the Hydrogen Initiative Bavaria. An MAN low-floor bus will be equipped with the components for a fuel cell drive system. The PEM fuel cell is developed by the power generation division of Siemens. Four fuel cell modules deliver a total electrical output of 120 kW to the two electric motors, which are linked by a summation gearbox by the Siemens Transportation Systems Division. MAN Technologie AG is responsible for the compressed hydrogen storage system allowing for a driving range of more than 250 km, while Linde AG takes care of the hydrogen periphery and delivers the hydrogen for the test operation scheduled for the beginning of the year 2000. Project coordination is done by Ludwig-Boelkow System-technik GmbH. The project is divided into four phases. The conceptual design phase is scheduled to last until the end of 1997. The partly overlapping system integration phase will end in the first quarter of 1999. The subsequent test and commissioning phase will prepare the test operation at the beginning of 2000 with a bus operator yet to be defined. (author)

  20. Music and Mind: In Memoriam Professor Carlo Alberto Pagni, MD, PhD: February 13, 1931 -March 1, 2009.

    Science.gov (United States)

    von Wild, Klaus R H

    2017-01-01

    Carlo Alberto Pagni, born in La Spezia, Italy, on February 13, 1931, was an eminent and respected professor of neurosurgery and chairman of the neurosurgical clinic of the University of Turin from 1980 to 2003. He died on March 1, 2009. As a professor of neurology and neurological surgery he was renowned as an expert on vascular, tumor, and functional neurosurgery. Beyond the Italian Neurosurgical Society, he was the doyen of functional neurosurgery, specializing in motor cortex stimulation for the treatment of focal dystonia, Parkinson's disease, and postictal spasticity and pain. His home was his castle, and his family was fundamental to his life. He shared with his wife, Sandra, his passion for piano playing and for their remarkable library, and together with friends, he and his wife enjoyed dinners with fine food and Barolo wines. Listening to this Grand Seigneur talking about and explaining the music of, above all, Ludwig van Beethoven, and Richard Wagner, one felt he was emotionally just "music and mind". You can imagine this from his books on music, chess, and neuroscience. Indeed, he adored playing correspondence chess worldwide. A sportsman too, he loved hiking, mountaineering, skiing, swimming, and fishing. Nature was his source for slowing down, for regenerating, and for collecting his strength for new projects and new challenges. Friends will remember Dr. Pagni as a Grand Seigneur.

  1. Zeit im Wandel der Zeit.

    Science.gov (United States)

    Aichelburg, P. C.

    Contents: Einleitung(P. C. Aichelburg). 1. Über Zeit, Bewegung und Veränderung (Aristoteles). 2. Ewigkeit und Zeit (Plotin). 3. Was ist die Zeit? (Augustinus). 4. Von der Zeit (Immanuel Kant). 5. Newtons Ansichten über Zeit, Raum und Bewegung (Ernst Mach). 6. Über die mechanische Erklärung irreversibler Vorgänge (Ludwig Boltzmann). 7. Das Maß der Zeit (Henri Poincaré). 8. Dauer und Intuition (Henri Bergson). 9. Die Geschichte des Unendlichkeitsproblems (Bertrand Russell). 10. Raum und Zeit (Hermann Minkowski). 11. Der Unterschied von Zeit und Raum (Hans Reichenbach). 12. Newtonscher und Bergsonscher Zeitbegriff (Norbert Wiener). 13. Die Bildung des Zeitbegriffs beim Kinde (JeanPiaget).14. Eine Bemerkung über die Beziehungen zwischen Relativitätstheorie und der idealistischen Philosophie (Kurt Gödel). 15. Der zweite Hauptsatz und der Unterschied von Vergangenheit und Zukunft (Carl Friedrich v. Weizsäcker). 16. Zeit als physikalischer Begriff (Friedrich Hund). 17. Zeitmessung und Zeitbegriff in der Astronomie (Otto Heckmann). 18. Kann die Zeit rückwärts gehen? (Martin Gardner). 19. Zeit und Zeiten (Ilya Prigogine, Isabelle Stengers). 20. Zeit als dynamische Größe in der Relativitätstheorie (P. C. Aichelburg).

  2. A Design Case: Developing an Enhanced Version of the Diffusion Simulation Game

    Directory of Open Access Journals (Sweden)

    Rodney Myers

    2010-01-01

    Full Text Available In this paper, we present a design case describing the creation of a new online version of the Diffusion Simulation Game (DSG. The DSG is a serious game that teaches change management strategies aligned with Rogers’ (2003 diffusion of innovations theory. The goal of the game is to promote the understanding of strategies that result in the adoption of an instructional innovation by the staff members of a fictional junior high school. The original board version of the game was created in the 1970s (Molenda and Rice, 1979 and was played as part of a course in the School of Education of a large Midwestern university. With the opening of a distance master’s program, the first online version of the game was developed in 2002 (Frick, Ludwig, Kim, & Huang, 2003. In order to overcome some of the limitations of the first online version, a new online version of the DSG was developed. This new version was rapidly prototyped first on paper and then in Flex Builder, ActionScript, PHP and MySQL. A rapid prototype approach (Tripp & Bichelmeyer, 1990 was utilized to iteratively design the user interface. In addition to describing the design process and rationale for design decisions, we also report results of play-tests and usability evaluations of seven recruited participants and how the information collected from these evaluations will help us to improve the current design.

  3. Physiologists against Theology: Science as a source of Secularization in ideology of scientific materialism in the 19th century

    Directory of Open Access Journals (Sweden)

    Vladislav Razdyakonov

    2017-12-01

    Full Text Available Jacob Moleschott (1822–1893, Karl Vogt (1817–1895 and Ludwig Buchner (1824–1899 are known as most notorious German spokesmen on behalf of “Science” in the mid —19th century. They are labelled in Russian historiography as “vulgar materialists” and are contrasted with dialectical materialists in their attitude to philosophy and science. This article shows how they used scientifi c conceptions of human physiology for the validation of their socio-political views, in particular on the role of religion in society and on the gradual secularisation of society. The article proposes critical reassessment of the category “vulgar materialists”, typical of current Russian historiography. It also aims to demonstrate their attitude to theology, philosophy, science and religion as main categories of their discourse. Finally, the article analyses scientifi c arguments in favour of the evolutionary development of society as well as reasons for the rejection of revolutionary practice. Although both “scientifi c materialism” and “scientifi c naturalism” do not meet the criteria of scientifi c ideology, scientifi c activity promotes secularisation by means of the extrapolation of its results to the social and political spheres.

  4. Three Hungarian researchers and three periods of the history and culture of the Albanian people

    Directory of Open Access Journals (Sweden)

    Myrvete Dreshaj-Baliu

    2016-11-01

    Full Text Available The object of this study is the contribution of three Hungarian researchers: the publicist, the editor and the historian Windisch (Karl Go$ lieb von Windisch, 1725 -1793; the outstanding historian, medievalist, latinist and germanist Thalloczy (Ludwig von Thallóczy, 1857-1916; and the geographer and ethnographer of international dimensions Nopcsa (Baron Nopcsha 1877-1933. Their selection is not random; it refl ects the up to now development in the science of Albanology and our goal as researchers and evaluators to place them on the Pantheon of the Albanian studies. These three names represent, at the same time, three particular dimensions of our national history: the fate of an ethnicity detached from its national territory in certain historical and cultural circumstances (Windisch; documentation of the Albanian space in a particularly controversial period of the Middle Ages in Albania and the Balkans (Thalloczy; and the wealthiest historical, ethnographic, material, spiritual and linguistic landscape of the Albanian people in the beginning of the twentieth century (Nopcsa. Therefore, let us state in the very beginning that recognition of their contribution also implies the recognition of some of the most important achievements of the Albanian studies.

  5. Franz Serafin Exner's Indeterminist Theory of Culture

    Science.gov (United States)

    Stöltzner, Michael

    By combining Ernst Mach's empiricism, Ludwig Boltzmann's atomism, and the relative frequency interpretation of probability, the Viennese physicist Franz Serafin Exner argued long before quantum mechanics that the basic laws of nature were of indeterministic nature and that the strict deterministic laws found on the macroscopic scale obtained in the limit of very many random events. The number of single events studied in humanistic disciplines was at best sufficient to ascertain weak regularities. But both science and the humanities were grounded in the law of large numbers, such that the world as a whole was governed by a global tendency towards the most probable state. Exner's unified outlook was not reductionist; rather it resembled the unification intended by Alexander von Humboldt's physical description of the world. Moreover, to Exner's lights, even culture was a natural product supervening on the various rising and declining peoples that exhibited a continuous ethical progress and the development of an objective scientific world view. By separating the individual microscopic and the ideal macroscopic levels, Exner's indeterminist theory simultaneously opposed the Spenglerian challenge against science and embraced his criticism of civilization and the death of the arts.

  6. Prevalence and natural history of ALK positive non-small-cell lung cancer and the clinical impact of targeted therapy with ALK inhibitors

    Directory of Open Access Journals (Sweden)

    Chia PL

    2014-11-01

    Full Text Available Puey Ling Chia,1 Paul Mitchell,1 Alexander Dobrovic,2–4 Thomas John1,2,4 1Department of Medical Oncology, Olivia-Newton John Cancer and Wellness Centre, Victoria, Australia; 2Ludwig Institute for Cancer Research, Austin Health, Victoria, Australia; 3Department of Pathology, University of Melbourne, Victoria, Australia; 4School of Cancer Medicine, La Trobe University, Victoria, Australia Abstract: Improved understanding of molecular drivers of carcinogenesis has led to significant progress in the management of lung cancer. Patients with non-small-cell lung cancer (NSCLC with anaplastic lymphoma kinase (ALK gene rearrangements constitute about 4%–5% of all NSCLC patients. ALK+ NSCLC cells respond well to small molecule ALK inhibitors such as crizotinib; however, resistance invariably develops after several months of treatment. There are now several newer ALK inhibitors, with the next generation of agents targeting resistance mutations. In this review, we will discuss the prevalence and clinical characteristics of ALK+ lung cancer, current treatment options, and future directions in the management of this subset of NSCLC patients. Keywords: anaplastic lymphoma kinase (ALK, gene rearrangements, lung cancer, kinase inhibitors, lung adenocarcinoma

  7. Intermedia and Intermittency

    Directory of Open Access Journals (Sweden)

    Veres Bálint

    2014-12-01

    Full Text Available It is commonly known that medial reflections have been initiated by attempts to secure the borders of discrete medial forms and to define the modus operandi of each essentialized medial area. Later on, the focus of study has shifted to plurimedial formations and the interactions between predefined medial genres. In the last few decades, taxonomic approaches to various multi-, inter-, and transmedial phenomena dominated the discussions, which offered invaluable support in mapping the terrain, but at the same time hindered the analysis of the ephemeral, time-dependent aspects of plurimedial operations. While we explore the properties of each medial configuration, we lose sight of the actual historical drivers that produce ever-new configurations. My thesis is that any discourse on intermediality should be paralleled by a discourse on cultural intermittency, and consequently, media studies should involve an approach that focuses on the “ecosystem” of the constantly renewing media configurations from the point of view of their vitalizing potential and capability to trigger heightened experiences. This approach draws much inspiration from K. Ludwig Pfeiffer’s media anthropology that gives orientation in my paper.

  8. Boltzmann und das Ende des mechanistischen Weltbildes

    CERN Document Server

    Renn, Jürgen

    2007-01-01

    Der Wissenschaftshistoriker und Physiker Jürgen Renn untersucht die Rolle des österreichischen Physikers und Philosophen Ludwig Boltzmann (18441906) bei der Entwicklung der modernen Physik. Boltzmann war einer der letzen Vertreter des mechanistischen Weltbildes und stand somit am Ende eines Zeitalters. Renn porträtiert den Wissenschaftler aber als einen Pionier der modernen Physik, dessen Beschäftigung mit den inneren Spannungen der klassischen Physik ihn visionär zukünftige Fragestellungen aufgreifen ließ. So befasste sich Boltzmann etwa mit den Grenzproblemen zwischen Mechanik und Thermodynamik, die ihn zur Entwicklung immer raffinierterer Instrumente der statistischen Physik antrieb, die schließlich zu Schlüsselinstrumenten der modernen Physik wurden. Boltzmanns Werk steht somit am Übergang vom mechanistischen Weltbild zur Relativitäts- und Quantentheorie. Der Aussage des viel bekannteren Physikers Albert Einstein, dass Fantasie wichtiger sei als Wissen, hält Jürgen Renn im Hinblick auf Leben ...

  9. Schubert and Beethoven - Adorno’s early antipods of the music in bougeois epoch

    Directory of Open Access Journals (Sweden)

    Jeremić-Molnar Dragana

    2012-01-01

    Full Text Available In this article the authors are reconstructing the dichotomies which the young Theodor Adorno was trying to detect in the music of the bourgeois epoch and personify in two antipodes - Franz Schubert and Ludwig van Beethoven. Although already a devotee of Arnold Schönberg and the 20th century music avantgardism, Adorno was, in his works prior to his exile from Germany (1934, intensively dealing with Schubert and his opposition towards Beethoven. While Beethoven was a bold and progressive revolutionary, fascinated by the “practical reason” and the mission to rise up and reach the stars, Schubert wanted none of it (almost anticipating the failure of the whole revolutionary project. Instead, he was looking backwards, to primordial nature and the possibility of man to participate in its mythic cycles of death and regeneration. The lack of synthesis between this two opposing tendencies in the music of early bourgeois epoch lead to the “negative dialectics” of Schönberg and 20th century music avantgardism and to the final separation of Beethovenian musical progress and Schubertian musical mimesis. [Projekat Ministarstva nauke Republike Srbije, br. 177019: Identiteti srpske muzike u svetskom kulturnom kontekstu, i br. 179035: Izazovi nove društvene integracije u Srbiji - koncepti i akteri

  10. The early modern kidney--nephrology in and about the nineteenth century. Part 1.

    Science.gov (United States)

    Eknoyan, Garabed

    2013-01-01

    The 19th century was a period of momentous scientific discoveries, technological achievements, and societal changes. A beneficiary of these revolutionary upheavals was medical empiricism that supplanted the rationalism of the past giving rise to early modern scientific medicine. Continued reliance on sensory data now magnified by technical advances generated new medical information that could be quantified with increasing precision, verified by repeated experimentation, and validated by statistical analysis. The institutionalization and integration of these methodologies into medical education were a defining step that assured their progress and perpetuation. Major advances were made in the nosography of diseases of the kidney, notably that of the diagnosis of progressive kidney disease from the presence of albuminuria by Richard Bright (1789-1858); and of renal structure and function, notably the demonstration of the continuity of the glomerular capsule with the tubular basement membrane by William Bowman (1816-1892), and the arguments for hemodynamic physical forces mediated glomerular filtration by Carl Ludwig (1816-1895) and for active tubular transport by Rudolf Heidenhain (1834-1897). Improvements in microscopy and tissue processing were instrumental in describing the cellular ultrastructure of the glomerulus and tubular segments, but their integrated function remained to be elucidated. The kidney continued to be considered a tubular secretory organ and its pathology attributed to injury of the interstitium (interstitial nephritis) or tubules (parenchymatous nephritis). © 2012 Wiley Periodicals, Inc.

  11. Conference-concert with Frédéric Bernachon on Thursday, 8 March at 6 pm

    CERN Multimedia

    Staff Association

    2018-01-01

    The Staff Association is pleased to invite you to an educational conference-concert of classical piano by Frédéric Bernachon « Beethoven : sa vie et son destin au cœur de la sonate Pathétique » on Thursday, 8 March at 6 pm Main Auditorium (500-1-001) Length: 60-90 minutes. Free entrance, cocktails served after the concert. External visitors, please contact the Staff Association for a visitor card: staff.association@cern.ch or +41 22 76 63738 With the help of a piano, Frédéric Bernachon proposes to explain the tragedy of Beethoven, as transmitted in his musical legacy. The listeners will get to experience Ludwig van Beethoven's destiny, suspense, drama and great questions in all their range and variety. After a careful introduction to listening to Sonate Pathétique, Frédéric Bernachon himself interprets this unique piece, through which Beethowen has chosen...

  12. Reaching for Success: Picasso’s Rise in the Market (The First Two Decades

    Directory of Open Access Journals (Sweden)

    Enrique Mallen

    2017-04-01

    Full Text Available This article explores the exhibitions of Picasso’s works in the first two decades of his artistic career, as well as the dealers and collectors who came into contact with them. It describes the relationship between Picasso and his first dealers, Pere Manyach, Berthe Weill, Clovis Sagot, Père Soulier, Ambroise Vollard, Daniel-Henry Kahnweiler, Georg Caspari, L. W. Guthier, Hans Goltz, Heinrich Thannhauser, Otto Feldmann, Alfred Flechtheim, Emil Richter, Gottfried Tanner, Michael Brenner, R. J. Coady, Léonce Rosenberg, Paul Rosenberg, etc.; as well as his first collectors, Leo and Gertrude Stein, Olivier Sainsère, Joachim Gasquet, Wilhelm Uhde, Herman Rupf, Vincenc Kramář, Frank Stoop, Hugo Perls, Edwin Suermondt, Dr. Paul Ferdinand Schmidt, Princess Mechtilde Lichnowsky, Henry Simms, Ludwig and Rosy Fischer, Professor Wilhelm Kreis, Adolf Erblösch, Justin K. Thannhauser, Sergei Ivanovich Shchukin, Ivan A. Morosov, etc. It also identifies all important Picasso expositions in this time period and how those dealers and collectors were involved in their arrangement. The information provided here has been excerpted from an exhaustive study of the critical literature on Pablo Picasso, as well as from published exhibition catalogues.

  13. Os jogos de linguagem do processo de produção da farinha de mandioca: uma investigação Etnomatemática

    Directory of Open Access Journals (Sweden)

    Alice Stephanie Tapia Sartori

    2016-06-01

    Full Text Available The article aims to analyze the rationality employed in the cassava flour farmers' production in a mill located in the Ibiraquera neighborhood of the Imbituba city in Santa Catarina - Brazil. In this study we will emphasize the planting and harvesting of cassava, and procedures of its processing into flour, based on a qualitative methodology of ethnographic inspiration. We conducted a description from direct observations and semi-structured interviews, in addition to field diaries, and photographic and filmic records. We analyze the material from the theoretical framework of Ethnomathematics. Our main goal with this approach is to distance us radically from attempts to frame popular knowledge in terms of the hegemonic knowledge of mathematics. This paper discusses the insurrection of subjugated knowledges within their specific language games. In this sense, we use the theories of Michel Foucault on subjugated knowledges and of Ludwig Wittgenstein in his second phase, about the language limits. Finally, we suggest that research can enable a reflection on pedagogical practices, in relation to the curriculum and ways of dealing with mathematical school knowledge and the knowledge produced by other ways of life.

  14. Ab initio modelling of transition metals in diamond

    International Nuclear Information System (INIS)

    Watkins, M; Mainwood, A

    2003-01-01

    Transition metals (TM) from the first transition series are commonly used as solvent catalysts in the synthesis of diamond by high pressure, high temperature processes. Ab initio calculations on these metals, in finite clusters of tetrahedrally coordinated carbon, enable us to investigate trends in their stability and properties. By carrying out systematic studies of interstitial, substitutional and semi-vacancy TM defects, we show that the electronic structure of the TMs is complicated by the presence of 'dangling bonds' when the TM disrupts the crystal lattice: interstitial defects conform to the Ludwig-Woodbury (LW) model, whilst substitutional and semi-vacancy defects move from approximating the LW model early in the transition series to approaching the vacancy model for the heavier metals. Multi-configurational self-consistent field methods allow genuine many-electron states to be modelled; for neutral interstitial, and all substitutional TMs, the crystal fields are found to exceed the exchange energies in strength. Consequently, low spin states are found for these defects. We find substitutional defects to be the most stable, but that semi-vacancy TMs are very similar in energy to the substitutional defects late in the transition series; interstitial defects are only metastable in diamond. Given appropriate charge compensators neutral and positively charged interstitial TM defects were stable, while negatively charged species appeared to be strongly disfavoured

  15. “The Suffering of an Ascetic”: On Linguistic and Ascetic Self-misunderstanding in Wittgenstein and Nietzsche

    Directory of Open Access Journals (Sweden)

    Peter K Westergaard

    2016-11-01

    Full Text Available This paper outlines an interpretation of Ludwig Wittgenstein’s remark in the Big Typescript in which he compares the philosopher bewitched by the workings of language to “the suffering of an ascetic”. The interpretation takes as its starting point Friedrich Nietzsche’s terse account of the philosopher, the history of philosophy, and his diagnosis of ascetic self-misunderstanding, from the Third Essay, “What do ascetic ideals mean?”, in On the Genealogy of Morality. In its assumption of an affinity between Wittgenstein’s remark and Nietzsche’s descriptions, and in its analysis, this paper introduces a “method of voice borrowing” to approach the question: “Wittgenstein and Nietzsche?” The juxtaposition of Wittgenstein’s conception of the philosopher’s linguistic self-misunderstanding with Nietzsche’s notion of the ascetic self-misunderstanding leads finally to the question of what is gained by introducing this method, and hence by reading Wittgenstein’s remark on the suffering of an ascetic with the help of Nietzsche’s voice.

  16. The Incertitude of Language and Life in the Poetry of Olvido García Valdés

    Directory of Open Access Journals (Sweden)

    Sharon Keefe Ugalde

    2012-06-01

    Full Text Available Two of Ludwig Wittgenstein’s formulations serve as guideposts for the analysis of the poetry of García Valdés: the concept of language-game and the Creation Mystic Experience, or seeing the world as a miracle. The paper first considers the language-game in terms of “unbound” or exempt language. The poet, recognizing the metamorphic nature of language, frees it from predetermined cultural content and, most notably, from grammatical rigidity, toying with ambiguity and fluidity through such techniques as juxtaposition, pronoun vagueness and ellipsis. The second part of the study considers the poet’s exploration of the ineffable, which embraces both the astonishment of being alive in the world—a mystic experience—and the mystery of death. The discovery of the wondrousness of the real comes through unhurried observation—principally visual, but also auditory and tactile—and is expressed with poignancy in language exempt from conventional constraints. When the focus is on mortality, additional textual strategies are present, for example, locating death in the body and placing a single sound within vast silence. What predominates is neither the astonishment of the real nor the menacing nearness of death but tension between the two; the ineffable balances on an axis of chiaroscuro.

  17. Restructuring terminated. Rotor technology is lookingt for an investor.; Restrukturierung abgeschlossen. Rotortechnik sucht Investor

    Energy Technology Data Exchange (ETDEWEB)

    Anon.

    2006-07-01

    The NOI Group was declared insolvent in July 2004. Attorney-at-law Rolf Rombach of Erfurt was appointed as the administrator for NOI-Rotortechnik GmbH, Nordhausen. The other former production facilities of the NOI Group in Germany, Scotland and Spain are no longer active. More than 1,000 rotor blades have been mass-produced in Nordhausen since the company was founded in 1999. The site covers an area of 60,000 m{sup 2}, including around 8,500 m{sup 2} of production facilities. More than Euro 10 million in total has been invested in the production facilities. The management - consisting of Niels Ludwig, Juergen Simon and Carsten Zaremba - is now taking the business successfully forward together with the administrator. With its 80-strong workforce, Rotortechnik produces top-quality rotor blades in the multi-megawatt class for German and international customers. During the past 20 months all the work processes have been critically examined, reorganised and constantly optimised. Following complete restructuring, Rotortechnik GmbH in Nordhausen is now ready to make a high-level comeback together with an investor. (orig.)

  18. Bauhäusler on the Franco-Spanish Border

    Directory of Open Access Journals (Sweden)

    Laura Martínez de Guereñu

    2016-10-01

    Full Text Available This article focuses on the travels of Bauhaus masters and instructors and on the transport of Bauhaus products to Spain in 1929, when the Franco-Spanish border was still culturally permeable. Ludwig Mies van der Rohe and Marcel Breuer introduced their tubular-steel furniture in the Spanish market. Mies and Lilly Reich designed the interiors of all German industrial sections at the Barcelona International Exposition, where the Bauhaus sent objects from its carpentry, metal, and weaving workshops. Josef and Anni Albers traveled to see the exhibition and then went to meet Vassily Kandinsky and Paul Klee, who spent over a month on holiday in the Côte Basque. Albers captured their trip in photo collages, Kandinsky registered his impressions in snapshots, while Klee wrote abundant correspondence and produced drawings. Focusing on the itineraries the Bauhäusler followed, along with the means by which they expressed their travel impressions, this article reveals the effect of travel in their later design attitudes and work. Significant cultural transfers between Germany and Spain took place in a critical moment of European history, suggesting that further developments of these learning experiences might have materialized later on both sides of the border, possibly even reaching across the Atlantic.

  19. Nobel prize winners from Siemens company

    International Nuclear Information System (INIS)

    Anon

    2007-01-01

    This paper deals with the history of discoveries and scientists which worked in the Siemens company. First Nobel prize winners from Siemens company was Gustav Ludwig Hertz from Hamburg. In his doctoral dissertation he deals with the study of collisions of electrons with molecules of gases. In the physics this experiment is known as 'Franc and Hertz experiment', which confirmed state of energy in Bohr theory and in 1925 he obtained Nobel prize. In 1945, as a director of the Department of physics in the research laboratories of Siemens, he constructed cyclotron kernel - magnet with mass of 80 tonnes. The second Nobel prize winner was Dennis Gabor worked in the Laboratory for measurement and medicinal technology in Siemensstadt (Berlin). When he tried to increase the resolution of electron microscopy he discovered the holography (method of 3-dimensional imaging). In 1971 he obtained the Nobel prize. The third scientist - Ernst Ruska discovered electron microscope. At Siemens, he was involved in developing the first commercially-produced electron microscope in 1939. In 1986, Ernst Ruska was awarded half of the Nobel Prize in Physics for his many achievements in electron optics.

  20. Representations of eyeglasses on Gothic winged altars in Austria.

    Science.gov (United States)

    Daxecker, F

    1997-01-01

    The oldest representation of eyeglasses in the German-speaking area is found on the altar of Tyrol Castle in the Museum Ferdinandeum in Innsbruck, Tyrol, on an altarpiece depicting the death of the Virgin Mary (1370-1372). Other representations of eyeglasses are found in Klosterneuburg, Lower Austria, Albrechtsaltar, collegiate collection, death of the Virgin (1439); St. Lorenzen ob Murau, daughter church St. Lorenzen, Styria, Katharinenaltar, Disputation (1455-1460); Pettau (Ptuj), Pokrajinjski Muzej, Slovenia (then belonging to the archbishopric of Salzburg), Conrad Laib, St. Bernardine of Siena with a spectacle case (1460-1465); on two altars by Michael Pacher: Pharisee, Gries near Bolzano (1471-1475), apostle mourning over the death of the Virgin Mary, and St. Luke, St. Wolfgang in Salzkammergut (1481); St. Florian, Upper Austria, collegiate collection, altar of the provost Leonhard Riesenschmid of St. Florian, death of the Virgin (1487); museum of Wilten monastery, Innsbruck, Ludwig Konraiter, St. Ottilie with reading stones and death of the Virgin Mary with reading apostle (1485-1490); Austrian Gallery Belvedere, Vienna, Master of Grossgmain, St. Augustine (1498); Austrian Gallery Belvedere, Vienna, Master of Mondsee, St. Augustine (1490-1500); Diocesan museum Graz, Styria, altar of Hirschegg, death of the Virgin (1503); Krenstetten, Lower Austria, Stefan-Altar, Disputation (1500-1520); Museum Ferdinandeum, Innsbruck, Matheis Stöberl, Jesus and the scribes with a spectacle case (early 16th century).

  1. Entanglement entropy after selective measurements in quantum chains

    Energy Technology Data Exchange (ETDEWEB)

    Najafi, Khadijeh [Department of Physics, Georgetown University,37th and O Sts. NW, Washington, DC 20057 (United States); Rajabpour, M.A. [Instituto de Física, Universidade Federal Fluminense,Av. Gal. Milton Tavares de Souza s/n, Gragoatá, 24210-346, Niterói, RJ (Brazil)

    2016-12-22

    We study bipartite post measurement entanglement entropy after selective measurements in quantum chains. We first study the quantity for the critical systems that can be described by conformal field theories. We find a connection between post measurement entanglement entropy and the Casimir energy of floating objects. Then we provide formulas for the post measurement entanglement entropy for open and finite temperature systems. We also comment on the Affleck-Ludwig boundary entropy in the context of the post measurement entanglement entropy. Finally, we also provide some formulas regarding modular hamiltonians and entanglement spectrum in the after measurement systems. After through discussion regarding CFT systems we also provide some predictions regarding massive field theories. We then discuss a generic method to calculate the post measurement entanglement entropy in the free fermion systems. Using the method we study the post measurement entanglement entropy in the XY spin chain. We check numerically the CFT and the massive field theory results in the transverse field Ising chain and the XX model. In particular, we study the post meaurement entanglement entropy in the infinite, periodic and open critical transverse field Ising chain and the critical XX model. The effect of the temperature and the gap is also discussed in these models.

  2. Entanglement entropy after selective measurements in quantum chains

    International Nuclear Information System (INIS)

    Najafi, Khadijeh; Rajabpour, M.A.

    2016-01-01

    We study bipartite post measurement entanglement entropy after selective measurements in quantum chains. We first study the quantity for the critical systems that can be described by conformal field theories. We find a connection between post measurement entanglement entropy and the Casimir energy of floating objects. Then we provide formulas for the post measurement entanglement entropy for open and finite temperature systems. We also comment on the Affleck-Ludwig boundary entropy in the context of the post measurement entanglement entropy. Finally, we also provide some formulas regarding modular hamiltonians and entanglement spectrum in the after measurement systems. After through discussion regarding CFT systems we also provide some predictions regarding massive field theories. We then discuss a generic method to calculate the post measurement entanglement entropy in the free fermion systems. Using the method we study the post measurement entanglement entropy in the XY spin chain. We check numerically the CFT and the massive field theory results in the transverse field Ising chain and the XX model. In particular, we study the post meaurement entanglement entropy in the infinite, periodic and open critical transverse field Ising chain and the critical XX model. The effect of the temperature and the gap is also discussed in these models.

  3. Sandvik's HM 150 roller in action on the world's largest conveyor bridge in the Lusatia region; Sandvik HM 150 auf der weltgroessten Foerderbruecke in der Lausitz im Einsatz

    Energy Technology Data Exchange (ETDEWEB)

    Waliczek, Sven; Raddatz, Ulrich [Sandvik Mining and Construction Central Europe GmbH, Essen (Germany)

    2010-09-15

    Prince Herrmann Ludwig Heinrich von Pueckler-Muskau, a landscape gardening genius, built the Muskau Park in the Lusatia region in 1817 - it is part of a UNESCO world heritage site today. In the same era, 1850, the first lignite was mined in the region and still today, Vattenfall, the Swedish company, extracts lignite without subsidies - in Jaenschwalde among other places, one out of the five opencast mines currently in operation. As one of the largest employers and apprenticing companies in East Germany, Vattenfall currently employs almost 8000 employees and about 800 apprentices. Sandvik Mining and Construction also plays a leading role - in the literal sense. At the Jaenschwalde location there are 320 sets of 5-roller garlands of HM150 formed rollers in action on the overburden conveyor bridge AFB 60m (Figure 1) - on belt five, the main belt conveyor (belt type 3000 ST3000-18:8, idler spacing approx. 800 mm) and on belt eight, the stockpile belt conveyor (belt type 2750 ST2500-18:8, idler spacing approx. 800 mm). It all began in the spring of 2004. Bernhard Hofmayer, Production Manager at Sandvik, introduced the HM150 formed roller to Vattenfall. The engineers were impressed by the completely new design and the innovative assembly technique. The discussion about the advantages and disadvantages of the component optimised formed roller were ready to begin. (orig.)

  4. Commissaire Moulin visits CERN

    CERN Multimedia

    CERN Bulletin

    2014-01-01

    The French actor and film-maker Yves Rénier was shown around the Laboratory on Friday 6 June by friends at CERN.   Yves Rénier at LEIR. (Photo: Ludwig Pregernig) A keen diver and star of the long-running French television police drama Commissaire Moulin, Yves Rénier took advantage of a stopover in Geneva on his way to the Red Sea to meet up with his friends from the CERN Diving Club, who were only too pleased to take him on a tour of the Laboratory. In the morning, Yves Rénier visited the CERN Control Centre (CCC), Linac2 and LEIR. After lunch at the brasserie in Restaurant No. 2, the actor continued his tour with the CERN Computer Centre, the SM18 superconducting magnet test facility, and lastly the ATLAS experiment. “Thank you so much for showing me around and introducing me to a world I knew so little about,” confided Yves Rénier. “It’s fascinating to see so many scientists of different cultures,...

  5. Wide-field fundus autofluorescence corresponds to visual fields in chorioretinitis patients

    Directory of Open Access Journals (Sweden)

    Seidensticker F

    2011-11-01

    Full Text Available Florian Seidensticker1, Aljoscha S Neubauer1, Tamer Wasfy1,2, Carmen Stumpf1, Stephan R Thurau1,*, Anselm Kampik1, Marcus Kernt1,*1Department of Ophthalmology, Ludwig-Maximilians-University, Munich, Germany; 2Department of Ophthalmology, Tanta University, Tanta, Egypt *Both authors contributed equally to this workBackground and objectives: Detection of peripheral fundus autofluorescence (FAF using conventional scanning laser ophthalmoscopes (SLOs is difficult and requires pupil dilation. Here we evaluated the diagnostic properties of wide-field FAF detected by a two-laser wavelength wide-field SLO in uveitis patients.Study design/materials and methods: Observational case series of four patients suffering from different types of posterior uveitis/chorioretinitis. Wide-field FAF images were compared to visual fields. Panretinal FAF was detected by a newly developed SLO, which allows FAF imaging of up to 200° of the retina in one scan without the need for pupil dilation. Visual fields were obtained by Goldmann manual perimetry.Results: Findings from wide-field FAF imaging showed correspondence to visual field defects in all cases.Conclusion: Wide-field FAF allowed the detection of visual field defect-related alterations of the retinal pigment epithelium in all four uveitis cases.Keywords: fundus autofluorescence (FAF, Optomap, wide-field scanning laser ophthalmoscopy, imaging, uveitis, visual field

  6. Résister au monde. Déclinaisons historiques de l’identité contemporaine dans quelques romans de Véronique Bergen

    Directory of Open Access Journals (Sweden)

    Judyta Zbierska-Mościcka

    2013-01-01

    Full Text Available Fictional autobiographies of a Belgian writer, Véronique Bergen, describing fates of outstanding characters albeit marginalised by history (Kaspar Hauser, Ludwig II of Bavaria, Ulrike Meinhof, may be interpreted as a metaphor of a contemporary man’s fate, a man caught, often against his will, in a course of political or social events. The characters described here adopt an active resistance stand against life, the stand defi ned by Bergen in her essay Résistances philosophiques, and manifested by striving to create one’s own, coherent world and a new language. In her reference to G. Deleuze, the author states that the said resistance is not only an act of existence but, also, an act of creation while creation of a new language involves, mainly, building of one’s own “I’. Identity of an individual is entangled within identity of a creator while reflection on language – with reflection on artistic medium.

  7. The Wondrous Universe Creation without Creator?

    CERN Document Server

    Börner, Gerhard

    2011-01-01

    The world as it is viewed from modern physics and cosmology has many strange and unexpected features. Often these are in stark contrast with our everyday experience or our preconceptions, such as the concept of space and time as finite and changeable. Nevertheless it is this strange world which is the fundamental basis of our existence. Therefore modern science also has a few things to say about the age-old questions: Who are we? – Where do we come from? – Where are we going? The author, an experienced scientist and teacher, presents the knowledge that we have about our world for non-experts. He takes us on a journey through cosmology and the quantum world of elementary particles. And he sketches the impact of the insights gained into philosophical assumptions and religious beliefs in these disciplines. In the end he asks the speculative question whether there is something beyond the limits of the natural sciences. Gerhard Börner is a Professor of Physics at the Ludwig Maximilians University in Munich a...

  8. The Chemical Abundances of Stars in the Halo (CASH) Project. II. A Sample of 14 Extremely Metal-poor Stars

    Science.gov (United States)

    Hollek, Julie K.; Frebel, Anna; Roederer, Ian U.; Sneden, Christopher; Shetrone, Matthew; Beers, Timothy C.; Kang, Sung-ju; Thom, Christopher

    2011-11-01

    We present a comprehensive abundance analysis of 20 elements for 16 new low-metallicity stars from the Chemical Abundances of Stars in the Halo (CASH) project. The abundances have been derived from both Hobby-Eberly Telescope High Resolution Spectrograph snapshot spectra (R ~15, 000) and corresponding high-resolution (R ~35, 000) Magellan Inamori Kyocera Echelle spectra. The stars span a metallicity range from [Fe/H] from -2.9 to -3.9, including four new stars with [Fe/H] ratios with decreasing metallicity. Two of these objects can be classified as CEMP-no stars, adding to the growing number of these objects at [Fe/H]CASH and are used to calibrate a newly developed, automated stellar parameter and abundance determination pipeline. This code will be used for the entire ~500 star CASH snapshot sample. We find that the pipeline results are statistically identical for snapshot spectra when compared to a traditional, manual analysis from a high-resolution spectrum. Based on observations obtained with the Hobby-Eberly Telescope, which is a joint project of the University of Texas at Austin, the Pennsylvania State University, Stanford University, Ludwig-Maximilians-Universität München, and Georg-August-Universität Göttingen. Based on observations gathered with the 6.5 m Magellan Telescopes located at Las Campanas Observatory, Chile.

  9. On the Minimum Induced Drag of Wings -or- Thinking Outside the Box

    Science.gov (United States)

    Bowers, Albion H.

    2011-01-01

    Of all the types of drag, induced drag is associated with the creation and generation of lift over wings. Induced drag is directly driven by the span load that the aircraft is flying at. The tools by which to calculate and predict induced drag we use were created by Ludwig Prandtl in 1903. Within a decade after Prandtl created a tool for calculating induced drag, Prandtl and his students had optimized the problem to solve the minimum induced drag for a wing of a given span, formalized and written about in 1920. This solution is quoted in textbooks extensively today. Prandtl did not stop with this first solution, and came to a dramatically different solution in 1932. Subsequent development of this 1932 solution solves several aeronautics design difficulties simultaneously, including maximum performance, minimum structure, minimum drag loss due to control input, and solution to adverse yaw without a vertical tail. This presentation lists that solution by Prandtl, and the refinements by Horten, Jones, Kline, Viswanathan, and Whitcomb.

  10. On Wings of the Minimum Induced Drag: Spanload Implications for Aircraft and Birds

    Science.gov (United States)

    Bowers, Albion H.; Murillo, Oscar J.; Jensen, Robert (Red); Eslinger, Brian; Gelzer, Christian

    2016-01-01

    For nearly a century Ludwig Prandtl's lifting-line theory remains a standard tool for understanding and analyzing aircraft wings. The tool, said Prandtl, initially points to the elliptical spanload as the most efficient wing choice, and it, too, has become the standard in aviation. Having no other model, avian researchers have used the elliptical spanload virtually since its introduction. Yet over the last half-century, research in bird flight has generated increasing data incongruous with the elliptical spanload. In 1933 Prandtl published a little-known paper presenting a superior spanload: any other solution produces greater drag. We argue that this second spanload is the correct model for bird flight data. Based on research we present a unifying theory for superior efficiency and coordinated control in a single solution. Specifically, Prandtl's second spanload offers the only solution to three aspects of bird flight: how birds are able to turn and maneuver without a vertical tail; why birds fly in formation with their wingtips overlapped; and why narrow wingtips do not result in wingtip stall. We performed research using two experimental aircraft designed in accordance with the fundamentals of Prandtl's second paper, but applying recent developments, to validate the various potentials of the new spanload, to wit: as an alternative for avian researchers, to demonstrate the concept of proverse yaw, and to offer a new method of aircraft control and efficiency.

  11. Extrañeza y escisión: Merleau Ponty, Wittgenstein y la dimensión constitutiva del cuerpo.

    Directory of Open Access Journals (Sweden)

    Magdalena Águeda Arnao Bergero

    2013-12-01

    Full Text Available Como efecto de la centralidad del problema mente-cuerpo en la historia del pensamiento occidental, el cuerpo ha ocupado un lugar de extrañeza como parte de lo que, recortado de lo distintivamente humano (la razón, el entendimiento, el alma, el cogito, nada tiene que ver con nuestra subjetividad. No obstante, no ha sido lo suficientemente advertido que el supuesto epistémico/ontológico de base de dicha dicotomía ha sido el de la escisión: esto es, el de vernos a nosotros mismos como escindidos del entorno (natural, social, histórico, cultural, del propio cuerpo y de los otros. La intención del presente artículo es mostrar el modo en que las filosofías de Ludwig Wittgenstein y Merleau Ponty lograron subvertir los efectos que dicho problema ocasionó sobre los modos de comprender nuestra subjetividad y entorno, volviendo a anclar la experiencia y acción humanas al mundo compartido, pre reflexivo,  y al propio cuerpo. 

  12. Functional Villa Tugendhat and its Geological Subsoil - Design of a New Geotourism Place

    Science.gov (United States)

    Duraj, Miloš; Cheng, Xianfeng; Niemiec, Dominik; Arencibia Montero, Orlando; Durďák, Jan

    2017-10-01

    Functionalist villa Tugendhat deserves to be one of the UNESCO heritage sites. The author of this building was a prominent German architect, Ludwig Mies van der Rohe, who accepted the contract from Greta and Fritz Tugendhat. From today’s perspective, this building is one of the most important pre-war works of this architect. The 1928 architectural design was subsequently very quickly completed and the construction was completed in 1930. The Tugendhat family lived in a villa until 1938. During World War II it was confiscated by German occupation forces. At the end of the war, it was used by the Red Army and later served for the state. During this period, this building did not avoid warfare or later destruction of both the building and parts of the facility. The importance of this building was recognized in 1969, when the villa was placed on the State List of Cultural Monuments. In the 80’s was the first major renovation of the building, which is often criticized. The second, last reconstruction took place in the years 2010 - 2012. During these reconnaissance works there were also old, temporarily calming landslides, which were subsequently solved. For this reason, the site is suitable for geotourism as an example of architectural monuments versus geological subsoil.

  13. IVth scientific congress of Central society of balneologists of Austria in Opatija, 1904.

    Science.gov (United States)

    Fischinger, Aleš; Fischinger, Janez; Fischinger, Duša

    2017-12-01

    The authors were interested in the lectures' themes, organisation, the course, and the accompanied activities at the balneology congress in Opatija in 1904. The congress was organised by the principle of the health resort at the time Professor Dr Julius Glax, and consisted of two separate parts. The first part was held in Opatija from October 13 until 15, 1904. There were lectures, auto-papers, summaries, reports, discussions, and the afternoon expert trip to Crikvenica by boat. In Opatija the participants were shown the spa park, the rehabilitation paths for patients with heart difficulties, marine baths Angiolona and Slatina, the covered spa Erzherzog Ludwig Viktor Bad, and of the health institution Zander Institute. At the accompanying exhibition the Austrian and German companies represented their products, among them still recognised Bayer, C. Reichert in Karl Zeiß. Additionally, the owner of the Zanderinstitut in Opatija Dr Isor Stein presented his own therapeutic aid exerciteur there. The first part of the congress concluded on October 15, 1904 with the great banquet in the hotel Stephanie.The second part of the congress was held from October 16 until 20, 1904. The expert trip was organised to the Austrian Riviera on the Pannonia ship. The participants visited attractions and health institutions in Mali Lošinj, Pula, Brijuni, Rovinj, Grado, Aquileia and Trieste, where they also had expert lectures. The closing ceremony of the second part of the congress was in Trieste, from where the participants returned to Vienna by the special train.

  14. Correlation between weather and incidence of selected ophthalmological diagnoses: a database analysis

    Directory of Open Access Journals (Sweden)

    Kern C

    2016-08-01

    Full Text Available Christoph Kern, Karsten Kortüm, Michael Müller, Florian Raabe, Wolfgang Johann Mayer, Siegfried Priglinger, Thomas Christian Kreutzer University Eye Hospital Munich, Faculty of Medicine, Ludwig-Maximilians-Universität München, Munich, Germany Purpose: Our aim was to correlate the overall patient volume and the incidence of several ophthalmological diseases in our emergency department with weather data. Patients and methods: For data analysis, we used our clinical data warehouse and weather data. We investigated the weekly overall patient volume and the average weekly incidence of all encoded diagnoses of “conjunctivitis”, “foreign body”, “acute iridocyclitis”, and “corneal abrasion”. A Spearman’s correlation was performed to link these data with the weekly average sunshine duration, temperature, and wind speed. Results: We noticed increased patient volume in correlation with increasing sunshine duration and higher temperature. Moreover, we found a positive correlation between the weekly incidences of conjunctivitis and of foreign body and weather data. Conclusion: The results of this data analysis reveal the possible influence of external conditions on the health of a population and can be used for weather-dependent resource allocation. Keywords: corneal injury, trauma, uveitis, conjunctivitis, weather

  15. Neural correlates of treatment outcome in major depression.

    LENUS (Irish Health Repository)

    Lisiecka, Danuta

    2012-02-01

    There is a need to identify clinically useful biomarkers in major depressive disorder (MDD). In this context the functional connectivity of the orbitofrontal cortex (OFC) to other areas of the affect regulation circuit is of interest. The aim of this study was to identify neural changes during antidepressant treatment and correlates associated with the treatment outcome. In an exploratory analysis it was investigated whether functional connectivity measures moderated a response to mirtazapine and venlafaxine. Twenty-three drug-free patients with MDD were recruited from the Department of Psychiatry and Psychotherapy of the Ludwig-Maximilians University in Munich. The patients were subjected to a 4-wk randomized clinical trial with two common antidepressants, venlafaxine or mirtazapine. Functional connectivity of the OFC, derived from functional magnetic resonance imaging with an emotional face-matching task, was measured before and after the trial. Higher OFC connectivity with the left motor areas and the OFC regions prior to the trial characterized responders (p<0.05, false discovery rate). The treatment non-responders were characterized by higher OFC-cerebellum connectivity. The strength of response was positively correlated with functional coupling between left OFC and the caudate nuclei and thalami. Differences in longitudinal changes were detected between venlafaxine and mirtazapine treatment in the motor areas, cerebellum, cingulate gyrus and angular gyrus. These results indicate that OFC functional connectivity might be useful as a marker for therapy response to mirtazapine and venlafaxine and to reconstruct the differences in their mechanism of action.

  16. Comparison of acoustic radiation force impulse imaging (ARFI) to liver biopsy histologic scores in the evaluation of chronic liver disease: A pilot study.

    Science.gov (United States)

    Haque, Mazhar; Robinson, Charlotte; Owen, David; Yoshida, Eric M; Harris, Alison

    2010-01-01

    Acoustic Radiation Force Impulse Imaging (ARFI) is a novel non invasive technique studying the localized mechanical properties of tissue by utilising short, high intensity acoustic pulses (shear wave pulses) to assess the mechanical response (tissue displacement), providing a measure of tissue elasticity. The aim of this study is to investigate the feasibility of ARFI imaging as a non-invasive method for the assessment of liver fibrosis compared to liver biopsy scores. A prospective blind comparison study of ARFI elastography (Virtual Touch Imaging., ACUSON S2000 Ultrasound Unit, Siemens, Mountain View CA) in a consecutive series of patients who underwent liver biopsy for assessment of fibrosis in chronic liver disease. ARFI shear-wave propagation velocity was measured in meters per second. Mean ARFI velocities were compared with both Batts-Ludwig (F0 to F4) and Modified Ishak scores (F0 to F4) for fibrosis in liver biopsy findings. Twenty-one patients with chronic liver disease (Hepatitis C (HCV) =16, Hepatitis B (HBV) = 1, both HCV and HBV = 1 Alcoholic liver disease (ALD) = 1, others = 2) underwent ARFI and liver biopsy on the same day. The Spearman correlation coefficients between the median values of the ARFI measurements and the histological fibrosis stage of the Modified Ishak score and Batts-Lud- (3) wig score were both highly significant (p shak score in chronic liver disease. It.s accuracy in prediction of severe fibrosis and cirrhosis is maximal in comparison with earlier stages.

  17. Construindo a noção de sintoma: articulações entre psicanálise e pragmática

    Directory of Open Access Journals (Sweden)

    Ana Carolina Silva

    Full Text Available Resumo Este trabalho pretende identificar pontos de aproximação entre a psicanálise e os estudos sobre a linguagem presentes na obra do filósofo austríaco Ludwig Wittgenstein. Para tal, parte-se da construção da noção de sintoma, sua definição no campo médico e psiquiátrico até sua demarcação no campo psicanalítico, elemento que só se define por sua relação com as práticas discursivas do sujeito. Ao introduzir a noção de jogos de linguagem, Wittgenstein destaca o caráter pragmático da linguagem: as regras de uso estabelecidas em determinado contexto conferem o significado a uma expressão linguística. Se para a psicanálise o sintoma implica uma articulação simbólica, é na relação entre significantes, própria do jogo linguístico, que se estabelecem as possibilidades de significação do próprio sujeito.

  18. A Wittgenstein Approach to the Learning of OO-modeling

    Science.gov (United States)

    Holmboe, Christian

    2004-12-01

    The paper uses Ludwig Wittgenstein's theories about the relationship between thought, language, and objects of the world to explore the assumption that OO-thinking resembles natural thinking. The paper imports from research in linguistic philosophy to computer science education research. I show how UML class diagrams (i.e., an artificial context-free language) correspond to the logically perfect languages described in Tractatus Logico-Philosophicus. In Philosophical Investigations Wittgenstein disputes his previous theories by showing that natural languages are not constructed by rules of mathematical logic, but are language games where the meaning of a word is constructed through its use in social contexts. Contradicting the claim that OO-thinking is easy to learn because of its similarity to natural thinking, I claim that OO-thinking is difficult to learn because of its differences from natural thinking. The nature of these differences is not currently well known or appreciated. I suggest how explicit attention to the nature and implications of different language games may improve the teaching and learning of OO-modeling as well as programming.

  19. The appeal to nature implicit in certain restrictions on public funding for assisted reproductive technology.

    Science.gov (United States)

    Carter, Drew; Braunack-Mayer, Annette

    2011-10-01

    Certain restrictions on public funding for assisted reproductive technology (ART) are articulated and defended by recourse to a distinction between medical infertility and social infertility. We propose that underlying the prioritization of medical infertility is a vision of medicine whose proper role is to restore but not to improve upon nature. We go on to mark moral responses that speak of investments many continue to make in nature as properly an object of reverence and gratitude and therein (sometimes) a source of moral guidance. We draw on the work of Ludwig Wittgenstein in arguing for the plausibility of an appeal to nature in opposition to the charge that it must contain a logical fallacy. We also invite consideration of the moral plausibility of some appeal to nature. Finally, we examine what follows in the case of ART. Should medicine respect as natural limits that should not be overcome: the need for a man and a woman in reproduction; menopause; and even declining fertility with age? We must first ask ourselves to what degree we should defer to nature in the conduct of medicine, at least in the particular if not the general case. This will involve also asking ourselves what we think is natural and in what instances and spirit might we defy nature. Divergent opinions and policies concerning who should receive ART treatment and public funding are more easily understood in view of the centrality, complexity and fundamental nature of these questions. © 2011 Blackwell Publishing Ltd.

  20. Language, games and the role of interpreters in psychiatric diagnosis: a Wittgensteinian thought experiment.

    Science.gov (United States)

    Thomas, P; Shah, A; Thornton, T

    2009-06-01

    British society is becoming increasingly culturally and linguistically diverse. This poses a major challenge to mental health services charged with the responsibility to work in ways that respect cultural and linguistic difference. In this paper we investigate the problems of interpretation in the diagnosis of depression using a thought experiment to demonstrate important features of language-games, an idea introduced by Ludwig Wittgenstein in his late work, Philosophical investigations. The thought experiment draws attention to the importance of culture and contexts in understanding the meaning of particular utterances. This has implications not only for how we understand the role of interpreters in clinical settings, and who might best be suited to function in such a role, but more generally it draws attention to the importance of involving members of black minority ethnic (BME) communities in working alongside mainstream mental health services. We conclude that the involvement of BME community development workers inside, alongside and outside statutory services can potentially improve the quality of care for people from BME communities who use these services.

  1. [Structured teaching of surgery the LMU model in Munich].

    Science.gov (United States)

    Chiapponi, C; Bruns, C J; Pilz, F; Kanz, K-G; Mutschler, W; Jauch, K-W; Siebeck, M

    2014-12-01

    The medical curriculum (MeCuM) of the Ludwig Maximilian University (LMU) in Munich is a dynamic curriculum aimed to support the learning process of all students with their different learning styles. It is based on interactive, activating teaching methods in order to increase students' interest, and on repetitive evaluation of teaching units to modify the teaching in order to meet students' needs and wishes. In this context the teaching of surgery at our faculty takes place. Besides interdisciplinary lessons where diseases are taught in cooperation with our colleagues from internal medicine, indications for surgery, complications and consequences of surgery for the patients are analysed in PBL tutorials, online cases, bedside teachings and practical teaching on the ward. Surgical skills like suturing are demonstrated in videos, practiced on models or during practical teaching on the ward and they are tested in OSCEs. During the "praktisches Jahr", the students in the last year of their medical studies are supposed to apply their practical skills besides repeating theoretical knowledge in order to pass the final examination. For this purpose they are taught in a revision course called "LMU-StaR" (revision course for the Staatsexamen). In this paper we describe in detail the teaching of surgery at our faculty. Georg Thieme Verlag KG Stuttgart · New York.

  2. [The medical literature of the Egyptian campaign].

    Science.gov (United States)

    Hutin, Jean-François

    2012-01-01

    Bonaparte's Egyptian Campaign (1798 - 1801), like all other episodes from the Napoleonic era, gave rise to an extensive literature on the subject, but most of all a significant medical literature. This fact is due to many reasons:--an important health service for this expeditionary corps of more than 36.000 men, with two main figures at its hea, Desgenettes and Larrey--but also with valuable subordinates like Assalini, Savaresi, Balme, Pugnet or Barbès.--A Commission for Science and Art, of which a few doctors and surgeons were members, but most of all pharmacists like Boudet or Rouyer--The presence in the field of Ludwig Frank, the nephew of the famous Johann Peter Frank.--The creation in Cairo of an Egyptian Institute and the publication of the masterly Description of Egypt and the establishment of printing houses.--The emergence of the myth of the Orient and its mysteries.--An extensive array of indigenous pathologies, which is characteristic of those countries. For instance: plague, dysentery, yellow fever, Egyptian ophthalmia, as well as more common diseases like tetanus, scurvy or venereal diseases. The main medical works that cover this period and its pathologies are skimmed.

  3. Anti-reductionism at the confluence of philosophy and science: Arthur Koestler and the biological periphery

    Science.gov (United States)

    Stark, James F.

    2016-01-01

    The Hungarian-born intellectual Arthur Koestler produced a wide-ranging corpus of written work throughout the mid twentieth century. Despite being the subject of two huge biographies in recent years, his long-standing engagement with numerous scientific disciplines remains unexplored. This paper situates Koestler's scientific philosophy within the context of mid-twentieth-century science and explores his relationship with key figures, including Dennis Gábor, C. H. Waddington, Ludwig von Bertalanffy and J. R. Smythies. The argument presented is threefold. First, surprisingly, serious scientists, particularly in the biological sciences, took Koestler's scientific work seriously; second, despite Koestler's best efforts, his allies could not agree on a single articulation of anti-reductionism; and third, the reductionist/anti-reductionist debates of the mid twentieth century constituted a battle for the authority to speak on behalf of ‘science’ that led Koestler into direct conflict with figures including Peter Medawar. By exploring the community associated with Koestler, the paper sheds new light on the status of scientific authority and the relationship between scientists’ metaphysical beliefs and their practices.

  4. Female pattern alopecia: current perspectives

    Directory of Open Access Journals (Sweden)

    Levy LL

    2013-08-01

    Full Text Available Lauren L Levy, Jason J Emer Department of Dermatology, Mount Sinai School of Medicine, New York, NY, USA Abstract: Hair loss is a commonly encountered problem in clinical practice, with men presenting with a distinctive pattern involving hairline recession and vertex balding (Norwood-Hamilton classification and women exhibiting diffuse hair thinning over the crown (increased part width and sparing of the frontal hairline (Ludwig classification. Female pattern hair loss has a strikingly overwhelming psychological effect; thus, successful treatments are necessary. Difficulty lies in successful treatment interventions, as only two medications – minoxidil and finasteride – are approved for the treatment of androgenetic alopecia, and these medications offer mediocre results, lack of a permanent cure, and potential complications. Hair transplantation is the only current successful permanent option, and it requires surgical procedures. Several other medical options, such as antiandrogens (eg, spironolactone, oral contraceptives, cyproterone, flutamide, dutasteride, prostaglandin analogs (eg, bimatoprost, latanoprost, and ketoconazole are reported to be beneficial. Laser and light therapies have also become popular despite the lack of a profound benefit. Management of expectations is crucial, and the aim of therapy, given the current therapeutic options, is to slow or stop disease progression with contentment despite patient expectations of permanent hair regrowth. This article reviews current perspectives on therapeutic options for female pattern hair loss. Keywords: androgenetic alopecia, female pattern hair loss, minoxidil, finasteride, antiandrogens, spironolactone

  5. The role of university hospitals as centers of excellence for shared health-care-delivery of in- and outpatients

    International Nuclear Information System (INIS)

    Adelhard, K.; Matzko, M.; Bruening, R.; Holzknecht, N.; Stark, V.; Reiser, M.

    2002-01-01

    Problem. Health care delivery in Germany has to face severe challenges that will lead to a closer integration of services for in- and out-patients. University hospitals play an important role due to their activities in research, education and health care delivery. They are requested to promote and evaluate new means and ways for health care delivery. Methods. The Institute of Clinical Radiology at the University Hospital of the Ludwig-Maximilians-University started teleradiological services for hospitals and general practices in January 1999 in the framework of the ''Imaging services - teleradiological center of excellence''. Legal, technical and organizational prerequisites were analyzed. Results. Networks between university hospitals and general practices are not likely to solve all future problems. They will, however, increase the availability of the knowledge of experts even in rural areas and contribute to a quality ensured health care at the patients home. Future developments may lead to international co-operations and such services may be available to patients abroad. Conclusion. Legal, technical and organizational obstacles have to be overcome to create a framework for high quality telemedical applications. University hospitals will play an important role in promoting and evaluating teleradiological services. (orig.) [de

  6. Disabled people - rehabilitation with sport

    Directory of Open Access Journals (Sweden)

    Tomasz Łosień

    2017-05-01

    Full Text Available Sport was used to complement  therapy in original form, improve of motor patterns and reeducate functions of people with disabilities. With a passing of time, sport evolved to integrated part of rehabilitation as an element of improvement. Moreover, he became as a tool to improve the social integration of people which finished the treatment or/and have deficits. We can notice the huge sport development of people with disabilities, which was initiated by Sir Ludwig Guttmann’s who claimed that view of sport is equal for people with disabilities and able-bodied people. The quality of physical activity of people with disabilities is indicated by motor preparation, training and sport (wellness, nutritionist, sport and exercise psychologist which currently is all the same except individual approach to particular dysfunction of the person with disability. Sport allow to develop not only physical sphere, but also teaches social integration, teamwork skills, self-discipline, improves the quality of life and outcome of the  ADL scale (activities of daily living scale of people with disabilities which do sport actively. The variety of sports disciplines and ability to use appropriate orthopedic stuff allows to activate people with every kind of disabilities and dysfunction.

  7. Wittgenstein y la teoría contemplativa del significado Observaciones a la tesis de Juan Abugattás

    Directory of Open Access Journals (Sweden)

    Álvaro Revolledo Novoa

    2011-05-01

    Full Text Available Este ensayo consiste en una lectura crítica de la interpretación que realiza el filósofo peruano Juan Abugattás en torno a la “teoría contemplativa” del Tractatus Logico Philosophicus (TLP de Ludwig Wittgenstein. En particular, se encarga de revisar la tesis de Bachiller de Juan Abugattás en la que afirma que la teoría del significado del TLP es reemplazada por la teoría del uso en la obra posterior de Wittgenstein. El objetivo central de este ensayo es demostrar que la teoría del significado del TLP no es, como pretende Abugattás, una mera teoría contemplativa, y que la teoría del significado de las Philosophische Bemerkungen (Ph. B., a diferencia de lo que sostiene Abugattás, aun mantiene intacta la perspectiva del TLP respecto de cómo el lenguaje puede permitirnos conocer el mundo. En ambos casos, sostengo que la teoría del significado del TLP obedece a una respuesta a la crítica lingüística de Mauthner y sus consecuencias en el plano del conocimiento.Palabras claves: Wittgenstein, teoría del significado, Tractatus Logico Philosophicus, lenguaje, conocimiento.

  8. Recent developments in the epidemiology and management of tuberculosis – new solutions to old problems?

    Directory of Open Access Journals (Sweden)

    Thaiss WM

    2012-01-01

    Full Text Available Wolfgang M Thaiss1, Cornelius C Thaiss2, Christoph A Thaiss31Christian-Albrechts-Universty, Kiel, 2Ludwig-Maximilians-University, Munich, Germany; 3Yale University School of Medicine, New Haven, CT, USAAbstract: Tuberculosis is an ancient human disease that is still a major cause of death and one of the most challenging public health problems worldwide. After decades of stagnancy, new public–private partnerships to fight the disease and the increasing awareness of a vicious circle between the tuberculosis epidemic and the obstruction of economic development have fuelled recent progress in our understanding of the disease. As a result, new strategies to improve management and treatment of tuberculosis have been initiated. At the same time, however, the devastating effect of human immunodeficiency virus on tuberculosis susceptibility and the rapid expansion of multidrug-resistant (MDR tuberculosis threaten to undermine the advances made by tuberculosis management programs. With an estimated 9 million new cases annually, tuberculosis affects a higher number of individuals worldwide than ever before. Here, recent developments in the epidemiology and management of tuberculosis are summarized and an overview is provided of emerging strategies to combat this ancient scourge.Keywords: tuberculosis, epidemiology, management, multidrug resistance, vaccine

  9. Radioiodination of monoclonal antibody intact anti-CEA

    International Nuclear Information System (INIS)

    Okada, H.; Souza, I.T.T.; Silva, C.P.G.

    1990-11-01

    The purpose of this study is to examine a convenient system that can be used to iodinate monoclonal antibodies which is rapid, simple, efficient and reproducible, and which can be accomplished in radiopharmaceutical laboratories. It is important to remember that antibodies are sensitive biochemicals, subject to losses of the activity that is essential to their mode of action, namely the ability to bind specific antigen. The advent of solid phase iodination agents has greatly expanded the range of gentle iodination techniques available for iodinating sensitive biological materials. The agent most widely used is the Iodogen (1,3,4,6 tetrachloro-3a-6a diphenylglycoluril) method. Anti-CEA 4C sub(11) IgG sub(2a,k) (prepared in the Ludwig Institute-Sao Paulo-Brazil ) is used as model to evaluate the Iodogen methodology. The miniature chromatographic system, also rapid, accurate, simple, efficient was elaborated to determine the labelling efficiency incorporation of iodine into immunoglobulin, and the radiochemical purity of sup(131)I-anti-CEA. (author)

  10. colectivos de pensamiento del Caribe colombiano

    Directory of Open Access Journals (Sweden)

    Yidy Páez Casariegos

    2008-01-01

    Full Text Available Juan Méndez Nieto es un medico judío-portugués formado en la Universidad de Salamanca, quien llega a Cartagena hacia 1.569, huyendo posiblemente de la Inquisición, desde Santo Domingo - por su condición de "cristiano nuevo;-. En Tierra Firme despliega una intensa actividad médica, en la cual se conjugan los saberes de una problemática modernidad peninsular con los saberes prehispánicos. En su obra, Discursos Medicinales (1.607-1.608 el primer texto de medicina escrito en estas tierras- se puede leer el interés de un "etnógrafo; por las condiciones socio-culturales del síntoma y la praxis del clínico sujeta a la tensión de un ethos "barroco‟ que arrastra en su diáspora los estilos de pensamiento protomodernos de ultramar que hacen crisis frente a los colectivos de pensamiento local dominados por las imágenes y los medios de coerción y punición del Santo Oficio. En este ensayo se intentará hacer una lectura hermenéutica de la vida y obra de Juan Méndez Nieto, utilizando como "determinativos; de interpretación las nociones de estilo y colectivo de pensamiento del médico y sociólogo de la ciencia, Ludwig Fleck.

  11. 'Tipping the Balance': Karl Friedrich Meyer, Latent Infections, and the Birth of Modern Ideas of Disease Ecology.

    Science.gov (United States)

    Honigsbaum, Mark

    2016-04-01

    The Swiss-born medical researcher Karl Friedrich Meyer (1884-1974) is best known as a 'microbe hunter' who pioneered investigations into diseases at the intersection of animal and human health in California in the 1920s and 1930s. In particular, historians have singled out Meyer's 1931 Ludwig Hektoen Lecture in which he described the animal kingdom as a 'reservoir of disease' as a forerunner of 'one medicine' approaches to emerging zoonoses. In so doing, however, historians risk overlooking Meyer's other intellectual contributions. Developed in a series of papers from the mid-1930s onwards, these were ordered around the concept of latent infections and sought to link microbial behavior to broader bio-ecological, environmental, and social factors that impact hostpathogen interactions. In this respect Meyer-like the comparative pathologist Theobald Smith and the immunologist Frank Macfarlane Burnet-can be seen as a pioneer of modern ideas of disease ecology. However, while Burnet's and Smith's contributions to this scientific field have been widely acknowledged, Meyer's have been largely ignored. Drawing on Meyer's published writings and private correspondence, this paper aims to correct that lacuna while contributing to a reorientation of the historiography of bacteriological epidemiology. In particular I trace Meyer's intellectual exchanges with Smith, Burnet and the animal ecologist Charles Elton, over brucellosis, psittacosis and plague-exchanges that not only showed how environmental and ecological conditions could 'tip the balance' in favor of parasites but which transformed Meyer thinking about resistance to infection and disease.

  12. New fossil seeds of Eurya (Theaceae from East Asia and their paleobiogeographic implications

    Directory of Open Access Journals (Sweden)

    Hai Zhu

    2016-06-01

    Full Text Available Eurya has an excellent fossil record in Europe, but it has only a few fossil occurrences in East Asia though this vast area houses the highest modern diversity of the genus. In this study, three-dimensionally preserved fossil seeds of Eurya stigmosa (Ludwig Mai from the late Pliocene of northwestern Yunnan, southwestern China are described. The seeds are compressed and flattened, slightly campylotropous, and nearly circular to slightly angular in shape. The surface of the seeds is sculptured by a distinctive foveolate pattern, consisting of funnel-shaped and finely pitted cells. Each seed valve contains a reniform or horseshoe-shaped embryo cavity, a characteristic condyle structure and an internal raphe. These fossil seeds represent one of the few fossil records of Eurya in East Asia. This new finding therefore largely extends the distributional ranges of Eurya during Neogene. Fossil records summarized here show that Eurya persisted in Europe until the early Pleistocene, but disappeared thereafter. The genus might have first appeared in East Asia no later than the late Oligocene, and dispersed widely in regions such as Japan, Nepal, and southwestern China.

  13. Moessbauer Spectroscopy: Elegance and versatility in chemical diagnostics

    Energy Technology Data Exchange (ETDEWEB)

    Guetlich, Philipp; Garcia, Yann, E-mail: guetlich@uni-mainz.d [Unite de Chimie des Materiaux Inorganiques et Organiques, Departement de Chimie, Universite Catholique de Louvain, Place L. Pasteur 1, 1348 Louvain la Neuve (Belgium)

    2010-03-01

    Dedicated to Professor Rudolf Ludwig Moessbauer on the occasion of his 80th birthday. Soon after the discovery of the recoilless nuclear resonance fluorescence by Rudolf L. Moessbauer some fifty years ago a new spectroscopic technique developed quickly on the basis of this resonance phenomenon as an excellent tool for the investigation of materials through electric and magnetic hyperfine interactions between electrons and suitable Moessbauer nu-clides. Many disciplines of solid state research have benefited from applications of the new tool for non-destructive phase analysis. Chemists in particular have recognized the information that can be derived from Moessbauer spectra regarding oxidation and spin state, molecular symmetry, bonding properties, magnetism, dynamic phenomena such as spin state switching, electronic transfer processes and other phase fluctuations to name a few. This Keynote Lecture presents highlights of chemical applications of Moessbauer spectroscopy selected from work during the past five decades which will demonstrate the elegance and versatility of the technique in the hands of (not only) chemists, but materials scientists in the broadest sense. The retrospect begins with studies in the early sixties on simple oxides and coordination compounds, where Moessbauer spectroscopy played a decisive role in solving unanswered questions, and concludes with fascinating current discoveries on the Planet Mars and most recent developments in the use of synchrotron radiation for nuclear resonance scattering (NFS, NIS).

  14. Brenda Escobar Guzmán De los conflictos locales a la guerra civil. Tolima a finales del siglo XIX.

    Directory of Open Access Journals (Sweden)

    Jean Paul Ruiz Martínez

    2016-01-01

    Full Text Available El libro es la tesis doctoral realizada por Brenda Escobar en la Universidad Ludwig-Maximilian de Múnich. En su trabajo, se discute la importancia historiográfica dada a la adscripción partidista como factor que dividió la sociedad colombiana, especialmente a la idea de que el “compromiso partidista definiría las acciones de los colombianos en el siglo xix, tanto de la gente humilde como de los notables locales” (pág. 25, sustentada de manera reiterativa en la obra de Fernán González. En oposición a esta concepción, e influenciada por los estudios subalternos, la autora propone que en el caso del Tolima durante la Regeneración el bipartidismo no fue el principal motivo de oposición entre los sectores populares, y que cuando existían adscripciones partidistas estas no determinaban las conductas hacia otros, pues habría tenido más importancia la defensa de los intereses inmediatos y la supervivencia que la pertenencia a unas redes clientelistas y la herencia de odios de partido.

  15. Paul Ehrenfest and the dilemmas of modernity.

    Science.gov (United States)

    van Lunteren, Frans H; Hollestelle, Marijn J

    2013-09-01

    This essay considers the highly ambivalent attitude of the Austrian-Dutch physicist Paul Ehrenfest toward contemporary developments in both science and society. On the one hand, he was in the vanguard of the quantum and relativity revolutions, supported industrialization and economic planning based on mathematical models, and, in general, cherished technocratic ideals. The essay highlights several influences that shaped his attitude in these respects, from his ties with the Philips Physics Laboratory and his sojourns in the United States to the utopian visions of H. G. Wells. On the other hand, he was extremely worried about the harmful consequences of contemporary changes in science and society, such as specialization, the growing pace of city life, and the increasing dependence on modern technologies, be they material or mathematical. In this regard, he agreed with cultural critics such as Max Nordau, Henri Bergson, Ostwald Spengler, and Ludwig Klages. Rather than attempting to solve this paradox, the essay suggests that this kind of ambiguity characterized a great deal of innovative science in the period.

  16. [Medical history as an academic subject at the Bamberg University].

    Science.gov (United States)

    Locher, W

    2000-01-01

    A full program of medicine was taught at the Catholic University of Bamberg (founded 1648 as the Academia Ottonia) from 1773 through 1803. Within this period of time, the History of Medicine was taught from 1790 through 1795 by Johann Baptist Dominicus Fin(c)k. This paper elucidates how in this instance protestant universities served as models for catholic universities. Interestingly, it was not the medical faculty itself which developed an interest in teaching medical history. Rather, it was Adalbert Friedrich Marcus (1753-1816), physician-in-waiting of the Prince-Bishop Franz Ludwig von Erthal and medical officer in the principality of Bamberg since June 22, 1790, who was charged by the Prince-Bishop with developing guidelines for medical education. The start of the History of Medicine lectures brought with it a heated dispute about an appropriate textbook. The discussion is evidence of a transition from historiography understood as an account of learned doctors of the past to a study of history in a modern sense.

  17. FRM-II: status of construction, licensing fuel tests

    International Nuclear Information System (INIS)

    Axmann, A.; Boening, K.; Nuding, M.; Didier, H.J.

    2001-01-01

    The research reactor FRM-II of the Technische Universitaet Muenchen is now ready for the nuclear start-up, but still waiting for the operational license. The high-flux neutron-source FRM-II (8 x 10 14 n/(s cm 2 ) is a unique tool for solid state physics and materials research by neutron scattering, positron annihilation experiments and activation analysis, as well as for fundamental physics, isotope production, silicone doping, cancer therapy by irradiation with fission neutrons and for tomography with fast and thermal neutrons. Reactor built in facilities as a hot source, a cold source, an uranium loaded converter plate producing an intense beam of fission neutrons, allow to expand the range of usable neutron energies far beyond the thermal spectrum. In addition, a source providing an intense beam of fission products is planned to be constructed by the Ludwig-Maximilians-Universitaet Muenchen and a source of ultra cold neutrons is planned by the Physics Department of the Technische Universitaet Muenchen. The reactor is already prepared for both of these facilities. (author)

  18. Do individual e do coletivo: sobre aproximações entre o pensamento de Freud e Marx

    Directory of Open Access Journals (Sweden)

    Patrícia Magri Granúzzio

    2011-01-01

    Full Text Available O objetivo deste artigo é discutir a aproximação teórica entre duas vertentes distintas de pensamento que, inicialmente, pode parecer improvável: a psicanálise e o marxismo. O texto discorre sobre a reflexão da gênesis do problema político, interpretando sociedade e indivíduo como inter-relação da natureza humana, conectando, a partir desse princípio, o problema político e o problema psicológico, este se situando como base original daquele. Portanto, no entrecruzamento de sociedade, poder político e natureza humana, expande-se um campo de investigação que se abre a diversas possibilidades, inclusive à aproximação teórica entre as ideias de Marx e Freud. Dentre diversos autores que discutem o freudomarxismo e o posicionamento de Sigmund Freud, diante das ideias de Karl Marx, será dada exclusividade a Wilhelm Reich, Herbert Marcuse e a Ludwig Marcuse. Para uma crítica às ideias de Herbert Marcuse e análise da inter-relação entre marxismo e psicanálise, por sua vez, recorre-se ao filósofo marxista Louis Althusser e a outros analistas e críticos dessas mesmas ideias.

  19. Myšlení pozdního Wittgensteina a gramatika náboženského diskursu

    Directory of Open Access Journals (Sweden)

    Jan Regner

    2014-10-01

    Full Text Available The aim of the present paper is to find a way of the theological method after Ludwig Wittgenstein’s remarks, especially in his Philosophical Investigations. As he maintains, language and human behaviour is connected, and so we cannot judge religious discourse without observing other nonverbal phenomena. We focused on works and authors who influenced Wittgenstein’s thoughts such as William James and James G. Frazer; and we briefly introduced to Wittgenstein’s argumentation against scientism. Hlavním cílem tohoto článku je najít podobu teologické metody, která by vzala v potaz pozdní myšlení Ludwiga Wittgensteina, zejména jeho Filosofická zkoumání. Rakouský autor je přesvědčen, že jazyk je úzce spojen s lidským jednáním, a proto není možné posuzovat náboženský diskurs, aniž bychom bedlivě pozorovali nonverbální projevy, které tento diskurs provázejí. Zaměřili jsme se na díla autorů, kteří ovlivnili Wittgensteinovo myšlení, jako byl William James nebo James G. Frazer, a představili jsme také Wittgensteinovu argumentaci proti scientismu.

  20. Wittgenstein jako socjolog codzienności [Wittgenstein as sociologist of everyday life

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    Katarzyna Gurczynska-Sady

    2014-09-01

    Full Text Available The question I would like to ask in this aritcle is: what is the source of human behaviour in everyday life? The question belongs to the field of philosophical anthropology and can be formulated also as following: what it the subject of human behaviour? The answer to this question seems to be obvious. Who if not the individual himself could be an animator of the things he does? Especially when we think of his everyday activities. In what other contexts, if not in the private sphere, human behavior would seem more dependent on the man himself? Setting up this question I tried to refute these obvious. I try to demonstrate that the source of human behavior has nothing to do with so called individual human will. I try to show that the meanings attach to human actions do not depend on an individal, even if it they take place "in the privacy of somebody's home”. I will try to prove it using Ludwig Wittgenstein's remarks concerning the voluntary and involuntary movements and Goffman's remark on human condition as an actor.

  1. Morell Mackenzie's Contribution to the Description of Spasmodic Dysphonia.

    Science.gov (United States)

    Lorch, Marjorie Perlman; Whurr, Renata

    2016-12-01

    Since the middle of the 20th century, most discussions of spasmodic dysphonia (SD) reference a paper by Ludwig Traube published in1871 as the first historical citation, crediting him with priority for this clinical syndrome. However, our recent research has determined that the original observation by Traube was published in 1864 and does not in fact describe what is currently recognized as SD. It appears that many clinics throughout Europe and North America were investigating and publishing observations on a range of voice disorders. The wider context of work on laryngeal disorders in the 1860s-1870s is considered. One of Traube's contemporaries, Morell Mackenzie, made significant contributions to the understanding of laryngeal movement disorder and its consequences for the voice. These will be examined to gain a clearer focus on the characterization of this disorder. The clinical descriptions published by Morrell Mackenzie in the 1860s provide details that conform quite closely to our current-day understanding of SD. The citation of Traube's "hysterical" patient links to mid 20th-century views of the functional nature of SD and the utility of psychiatric treatment. The description presented by Mackenzie is consistent with current views of SD as a movement disorder. © The Author(s) 2016.

  2. Reflexões sobre a contribuição da Carnot à primeira lei da termodinâmica Reflections on the contribution of Carnot to the first law of thermodynamics

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    Cássius K. Nascimento

    2004-06-01

    Full Text Available The classical interpretations of Nicolas Léonard Sadi Carnot on some physical principles involved in the operation of heat engines were fundamental to the development and formulation of the Second Law of Thermodynamics. Moreover, an accurate historical survey clearly reveals that Carnot was, by that time, also well aware about some new concepts, which were further worked out by other scientists to lead to what was, some time later, known as the mechanical equivalent of heat and the conservation of energy. Benoit Paul Émile Clapeyron recognized these original concepts in the first of Carnot´s monographs, published in 1824, but no explicit citation is found in any post-Carnot classical texts dealing with the First Law of Thermodynamics, including those by Julius Robert Mayer, James Prescott Joule and Hermann Ludwig Ferdinand von Helmholtz. The main objective of the present work is to point out some historical evidences of the pioneering contribution of Carnot to the modern concept of the First Law of Thermodynamics.

  3. Da inteligência parcial ao pensamento completo: desafios da ciência e da sociedade contemporânea DOI:10.5007/2175-7984.2011v10n19p41

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    Maria Cecília de Souza Minayo

    2011-10-01

    Full Text Available Este artigo apresenta uma discussão sobre várias noções teóricas e metodológicas que hoje fazem parte do vocabulário do mundo das ciências e das práticas profissionais como: multidisciplinaridade, multiprofissionalidade, interdisciplinaridade, transdisciplinaridade e pensamento complexo. Embora todos esses termos sejam tratados no texto, mesmo que brevemente, o artigo aprofunda a contribuição das teorias da complexidade, a partir de seus pensadores mais renomados: Ludwig von Bertalanffy, Henri Atlan, Ilya Prigogine e Edgard Morin. Entende-se que qualquer esforço de interação entre ciências e práticas é bem vindo para ampliar e aprofundar o conhecimento dos objetos. No entanto, essa interação precisa ser cada vez mais iluminada por conceitos das teorias complexas que apontam um futuro diferente para todas as áreas das ciências, frente a questões como incerteza, ruídos e crises que abrem possibilidades de escolhas e questionam as características principais das ciências tradicionais como regularidades, previsibilidade e verdades estabelecidas.

  4. Teaching physics in a physiologically meaningful manner

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    Michael Plomer

    2010-09-01

    Full Text Available The learning outcome of a physics laboratory course for medical students was examined in an interdisciplinary field study and discussed for the electrical physiology (“Propagation of Excitation and Nerve Cells”. At the Ludwig-Maximilians-University of Munich (LMU at a time about 300 medicine students were assessed in two successive years. Students from the control group worked with standard experiments, while students from the treatment group performed newly developed “addressee-specific” experiments, designed to guide students to transfer physics knowledge to physiological problems. The assessment took place within the laboratory course on physiology, after the students had finished their laboratory classes in physics, and consisted of the construction of a concept map with additional multiple choice questions. The results showed that standard physics experiments are not adequate for teaching students to transfer physical principles to physiology. Introducing new addressee-specific experiments enriched the physics laboratory course by improving student attitudes toward physics and demonstrating better ability of students to relate concepts of physics and medicine, and overall to improve their understanding of the physics taught in the course.

  5. Illusionists

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    N.J Wade

    2014-08-01

    Full Text Available Illusions have been displayed in art for millennia but they were not addressed seriously by visual science until the mid-nineteenth century when Johann Joseph Oppel referred to the small spatial distortions as ‘geometrical optical illusions’. Many of the illusion figures described thereafter bear the names of those who illustrated them. Original forms of the illusions were shown together with illusory portrayals of those who described them. These included (in chronological sequence: Jan Evangelista Purkyně, Louis Albert Necker, Michel Eugène Chevreul, Adolf Fick, Johann Karl Friedrich Zöllner, Johann Christian Poggendorff, Karl Ewald Konstantin Hering, August Kundt, Joseph-Rémi-Léopold Delbæuf, Ernst Mach, Hermann Ludwig Ferdinand Helmholtz, Ludimar Hermann, Wilhelm von Bezold, Henri Beaunis, Franz Carl Müller-Lyer, Theodor Lipps, Armand Thiéry, Wilhelm Maximilian Wundt, Hugo Münsterberg, Friedrich Schumann, Hermann Ebbinghaus, Edward Bradford Titchener, Joseph Jastrow, James Fraser, Mario Ponzo, Edgar Rubin, Matthew Luckiesh, Friedrich Sander, Walter Ehrenstein, Adelbert Ames, Richard Gregory, Gaetano Kanizsa, Michael White, Roger Shepard, and Bernd Lingelbach.

  6. Self-Assertion in the Public Sphere: The Jewish Press on the Eve of Legal Emancipation

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    Dieter J. Hecht

    2016-08-01

    Full Text Available Jews like Adolf Fischhof and Ludwig August Frankl were prominent participants in the revolution of 1848. Their speeches, poems, and portraits circulated in Vienna and throughout the Empire. With the suppression of the revolution, most of these prominent Jews had to either leave Vienna or retreat to the private sphere. Only in the late 1850s did Jews regain their public presence, starting with the opening of the Leopoldstaedter Tempel in 1858 and the building of the Ringstrasse from 1860 onwards. Many Jews hoped that the new liberal era would grant them civil rights and legal emancipation. Jewish intellectuals and journalists supported this struggle from within and outside the growing Jewish community. An important weapon in their struggle were Jewish newspapers. These newspapers not only provided information, but also served as mouthpieces for different Jewish movements. They featured biographies with portraits (in words and images of distinguished Jewish leaders (mostly men and a few women, which were supposed to present the social achievements of a certain group within Jewish society to a broader audience. In fact, these portraits served as a form of self-assertion for the publisher as well as for the audience. It projected the message that Jews not only merited emancipation, but also struggled for it on various levels. The paper therefore addresses questions of biography and the (Jewish identity these portraits at once reflected and shaped.

  7. Less is More: unveiling the functional core of hematopoietic stem cells through knockout mice

    Science.gov (United States)

    Rossi, Lara; Lin, Kuanyin K.; Boles, Nathan C.; Yang, Liubin; King, Katherine Y.; Jeong, Mira; Mayle, Allison; Goodell, Margaret A.

    2012-01-01

    Summary Hematopoietic stem cells (HSCs) represent one of the first recognized somatic stem cells. As such, nearly 200 genes have been examined for roles in HSC function in knockout mice. In this review, we compile the majority of these reports to provide a broad overview of the functional modules revealed by these genetic analyses and highlight some key regulatory pathways involved, including cell cycle control, TGF-β signaling, Pten/AKT signaling, Wnt signaling, and cytokine signaling. Finally, we propose recommendations for characterization of HSC function in knockout mice to facilitate cross-study comparisons that would generate a more cohesive picture of HSC biology. In the field of design, the minimalist movement stripped down buildings and objects to their most basic features, a sentiment that architect Ludwig Mies van der Rohe summarized in his motto “less is more”. By depleting HSCs of specific genes, knockout studies transpose the minimalist approach into research biology, providing insights into the essential core of genetic features that is indispensable for a well-functioning hematopoietic system. PMID:22958929

  8. Thermodynamics of Highly Concentrated Aqueous Electrolytes: Based on Boltzmann's eponymous equation

    Energy Technology Data Exchange (ETDEWEB)

    Ally, Moonis Raza [ORNL

    2018-05-01

    This sharply focused book invites the reader to explore the chemical thermodynamics of highly concentrated aqueous electrolytes from a different vantage point than traditional methods. The book's foundation is deeply rooted in Ludwig Boltzmann's eponymous equation. The pathway from micro to macro thermodynamics is explained heuristically, in a step-by-step approach. Concepts and mathematical formalism are explained in detail to captivate and maintain interest as the algebra twists and turns. Every significant result is derived in a lucid and piecemeal fashion. Application of the theory is exemplified with examples. It is amazing to realize that Boltamann's simple equation contains sufficient information from which such an elaborate theory can emerge. This book is suitable for undergraduate and graduate level classes in chemical engineering, chemistry, geochemistry, environmental sciences, and those studying aerosol particles in the troposphere. Students interested in understanding how thermodynamic theories may be developed would be inspired by the methodology. The author wishes that readers get as much excitement reading this book as he did writing it.

  9. Edukacja etyczna zorientowana na współpracę w kontekście neoliberalnych transformacji [Ethical education centered on cooperation in the context of neoliberal transformations

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    Danuta Anna Michałowska

    2014-03-01

    Full Text Available New problems appear for the development of individuals and the society in the context of global neoliberal transformations, international financial institutions as well as economic, political, technological, communication and cultural changes. It is necessary to make a reflection when we observe the unethical consequences of neoliberalism in today’s world and the influence it has on educational policy, especially on ethical education, as well as teaching and upbringing issues. In this paper an attempt was made to find alternative educational solutions, especially in the field of ethical education, that would encourage the development of individuals and democratic society. The author used the theory of human behaviors (Michael Tomasello and based on this theory – the concept of shared intentionality, which is promoted by Hans-Ludwig Kroeber, to show some alternatives for ethical education. The conclusions derived from this analysis provide a new perspective on the structure and quality of education and especially on the cognitive and ethical development of young people and also their value system. Cognitive and ethical education in cooperative and democratic community, based on concept of shared intentionality, seems to be one of alternatives to the neoliberal vision of individuals and society.

  10. Female pattern alopecia: current perspectives

    Science.gov (United States)

    Levy, Lauren L; Emer, Jason J

    2013-01-01

    Hair loss is a commonly encountered problem in clinical practice, with men presenting with a distinctive pattern involving hairline recession and vertex balding (Norwood-Hamilton classification) and women exhibiting diffuse hair thinning over the crown (increased part width) and sparing of the frontal hairline (Ludwig classification). Female pattern hair loss has a strikingly overwhelming psychological effect; thus, successful treatments are necessary. Difficulty lies in successful treatment interventions, as only two medications – minoxidil and finasteride – are approved for the treatment of androgenetic alopecia, and these medications offer mediocre results, lack of a permanent cure, and potential complications. Hair transplantation is the only current successful permanent option, and it requires surgical procedures. Several other medical options, such as antiandrogens (eg, spironolactone, oral contraceptives, cyproterone, flutamide, dutasteride), prostaglandin analogs (eg, bimatoprost, latanoprost), and ketoconazole are reported to be beneficial. Laser and light therapies have also become popular despite the lack of a profound benefit. Management of expectations is crucial, and the aim of therapy, given the current therapeutic options, is to slow or stop disease progression with contentment despite patient expectations of permanent hair regrowth. This article reviews current perspectives on therapeutic options for female pattern hair loss. PMID:24039457

  11. Mechanical and Controlled PRP Injections in Patients Affected by Androgenetic Alopecia.

    Science.gov (United States)

    Gentile, Pietro; Garcovich, Simone; Scioli, Maria Giovanna; Bielli, Alessandra; Orlandi, Augusto; Cervelli, Valerio

    2018-01-27

    23 patients (18 male and 5 female) aged 21-70 years who displayed male pattern hair loss (MPHL) in Stage 1 to Stage 5 as determined by the Norwood-Hamilton classification scale, and female pattern hair loss (FPHL) in Stage 1 to Stage 2 as determined by the Ludwig classification scale, were treated with non-activated autologous platelet-rich plasma (A-PRP). Autologous blood (55 mL) was harvested using sodium citrate as an anticoagulant. A-PRP (23 mL) was produced for all cases using a closed system according to the transfusion service protocol. Following centrifugation (260 x g for 10 min) the A-PRP was inserted in a laser light selector device, and after the centrifugation, 9 mL of A-PRP was collected. The scalp of the patients affected by androgenetic alopecia (AGA) was divided into four areas (frontal, parietal, vertex, and occipital); local anesthesia was not performed. Interfollicular A-PRP injections (0.2 mL x cm 2 ) were performed by controlled and mechanical injections scheduled at a depth of 5 mm using a medical injector gun. Treatment sessions were performed with a 30-day interval. For each patient, three treatment sessions were performed. PRP was injected in the androgen-related areas of scalp affected by hair loss. Placebo (normal saline solution) was loaded in another syringe (10 mL) and injected on the adjacent side in a similar fashion.

  12. A history of the ideas of theoretical physics essays on the nineteenth and twentieth century physics

    CERN Document Server

    D’Agostino, Salvo

    2000-01-01

    This book presents a perspective on the history of theoretical physics over the past two hundreds years. It comprises essays on the history of pre-Maxwellian electrodynamics, of Maxwell's and Hertz's field theories, and of the present century's relativity and quantum physics. A common thread across the essays is the search for and the exploration of themes that influenced significant con­ ceptual changes in the great movement of ideas and experiments which heralded the emergence of theoretical physics (hereafter: TP). The fun. damental change involved the recognition of the scien­ tific validity of theoretical physics. In the second half of the nine­ teenth century, it was not easy for many physicists to understand the nature and scope of theoretical physics and of its adept, the theoreti­ cal physicist. A physicist like Ludwig Boltzmann, one of the eminent contributors to the new discipline, confessed in 1895 that, "even the formulation of this concept [of a theoretical physicist] is not entirely without...

  13. The Antarctic holothurian genus Echinopsolus Gutt, 1990 (Dendrochirotida, Cucumariidae): brood pouches, spermatozoa, spermatozeugmata and taxonomic implications.

    Science.gov (United States)

    Bohn, Jens Michael; Heß, Martin

    2014-07-29

    An examination of seven Antarctic brooding cucumariid and psolid holothurian species revealed a variety of characters all of them have in common: (1) All are gonochoric. (2) A genital papilla is present on the oral disc (permanent and digitiform in males). (3) Females brood their offspring in five anterior interradial brood pouches that are situated at the transition of body to introvert. (4) Multiple spermatozoa are always bundled to bunch-like spermato-zeugmata. (5) The spermatozoa have a fusiform head and a hollow cylinder-like mid-piece encircling the anterior end of the flagellum. This combination of characters so far is unique, and indicates a close relationship based on common origin. As a consequence, we unite all species sharing this set of synapomorphies in the genus Echinopsolus Gutt, 1990. The herewith included species are: E. acanthocola Gutt, 1990, E. acutus (Massin, 1992) comb. nov., E. charcoti (Vaney, 1906) comb. nov., E. koehleri (Vaney, 1914) comb. nov., E. mollis (Ludwig & Heding, 1935) comb. nov., E. parvipes Massin, 1992 and E. splendidus (Gutt, 1990) comb. nov.. Because the current assignment of Echinopsolus to the family Psolidae can not be retained, the genus is tranferred to the family Cucumariidae, as relationships to taxa within this family are obvious. The peculiar spermatozoa and spermato-zeugmata of all Echinopsolus species are described using light- and electron-microscopical techniques and the results are evaluated and discussed concerning their taxonomy and phylogeny. 

  14. Silence, an Eye of Knowledge

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    Mehdi Aghamohammadi

    2017-04-01

    Full Text Available One of the conspicuous features of the twentieth-century West was silence. This idea could be supported by examining reflections of Ludwig Wittgenstein, Fritz Mauthner, John Cage, Samuel Beckett, Ihab Hassan, Franz Kafka, Wassily Kandinsky, Jean-Paul Sartre, Virginia Woolf, Wolfgang Iser, Jacques Derrida, and Pierre Macherey. To me, silence is not a mere theory, but rather a phenomenon from which we can get practical benefits. I believe silence is an eye, eye of knowledge. We can broaden our knowledge of the world through silence. To convey the idea that silence is an eye, I have concocted the word slence, where  has replaced the letter i and stands for the eye. This means knowledge can enable us to see, thereby acquiring knowledge of, what used to be invisible, and accordingly unknowable. In other words, through silence, we can achieve a certain type of literacy. I substantiate this claim by exploring the Horus myth, Ojo de Dios, John Cage’s 4' 33", the nature of Expressionist paintings, Hinduism, thoughts of Hermes Trismegistus and Ibn al-Arabi, and practices of Mohammad, the prophet of Islam.

  15. The nuclear phase-out and its consequences

    International Nuclear Information System (INIS)

    Ludwigs, Markus

    2016-01-01

    As a lesson from the Fukushima nuclear disaster, a radical change has taken place in climate and energy policy in Germany since 2011. This is characterized by the phase-out of the nuclear energy, which is fixed by the 13th Atomic Enforcement Act, by the end of 2022. This entails a multitude of complex legal questions and subsequent problems. The latest decisions are the forthcoming decisions of the BVerfG on the constitutional consistency of the nuclear phase-out law and nuclear fuel tax, Vattenfall's much discussed arbitration award before the ICSID arbitration court, and controversial legal questions both in the context of the decommissioning and dismantling of nuclear power plants and the disposal of highly radioactive waste. In addition, the moral-ethical evaluation of the nuclear phase-out and the power turn-around is the focus of the interdisciplinary approach. The problem clusters are analyzed by the contributions of the anthology. He documents a conference organized by Professor Dr. Markus Ludwig, which took place on April 8, 2016, at the University of Wuerzburg, within the framework of a project funded by the Fritz Thyssen Stiftung (''The Law of the Energy Transition''). [de

  16. [Complicities and ambivalences of psychiatry: Münsterlingen and the 1954 feast of fools].

    Science.gov (United States)

    Basso, Elisabetta

    2017-01-01

    In March 1954, Foucault visited the psychiatric asylum of Münsterlingen (Canton Thurgau), on the Swiss side of Lake Constance. Münsterlingen was the chosen place of activity for well-known psychiatrists, including Hermann Rorschach (1910-1913), and it became famous in the history of psychiatry especially through the work of Roland Kuhn, who was active in the asylum from 1939 to 1979. Kuhn was an expert in the Rorschach psycho-diagnostic test, as well as the discoverer of the first antidepressant in the early 1950s. He was also very close to Ludwig Binswanger, whose anthropological approach to mental illness had a strong influence on his own psychiatric practice. It is precisely in order to meet Kuhn and Binswanger that the young Foucault went to Switzerland, at a time when he was interested in philosophical anthropology and "existential psychopathology". Foucault's visit took place during the Carnival at the asylum, when the patients leave the hospital wearing the masks that they have made up and created. © 2017 médecine/sciences – Inserm.

  17. Kahulugan at Kairalan

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    Napoleon M. Mabaquiao Jr.

    2000-12-01

    Full Text Available This essay is a general analysis of how certain ways of understanding the meaningfulness of words (or how certain ways of explaining how words acquire meaning can affect beliefs regarding what exists in the world. The main focus is the philosophical controversy regarding the meaning of general terms. Accordingly, traditional approaches to this issue disagree on the kinds of entities that ought to exist in order for these terms to be meaningful. The author's analysis of this controversy proceeds as follows. First, it is explained how philosophers classify entities into several kinds and how they generally argue in support of their preference for certain types of entities over others. This discussion also distinguishes the method of linguistic analysis from other philosophical methods in dealing with ontological issues (or issues concerning existence. Then, the claims and arguments of the traditional accounts of the meaning of general terms are presented and explained. Lastly, these accounts are criticized using the perspective of the use theory of meaning of the philosopher Ludwig Wittgenstein. Among others, it is shown that the said accounts all assume the referential theory of meaning, which Wittgenstein strongly criticizes. At the latter part, the author also gives his reflections, in the light of this discourse, on the concept of Filipino as it relates to the issue of national identity.

  18. About the specialized myocardial conducting tissue.

    Science.gov (United States)

    de Micheli Serra, Alfredo; Iturralde Torres, Pedro; Aranda Fraustro, Alberto

    2013-01-01

    The chronological succession of discoveries on the location and structure of the atrio-ventricular conducting system are described. The starting point of this system is located in the sinus atrial node, identified by the English scientists A. Keith and M. W. Flack in 1907. The atrioventricular conducting system was pointed out by the Swiss physician Wilhelm His Jr. in 1893. The atrioventricular node (AV) was first identified by the Japanese pathologist Sumao Tawara and his German professor Ludwig Aschoff in 1906. Likewise the structure and routes of the three internodal bundles are described. These bundles include: Bachmann's bundle (1916) connecting the right with the left atrium and the AV node; the middle Wenckebach's bundle (1910) and the posterior or Thörel's bundle (1910), extending from the region of the sinus atrial node towards the posterior margin of the AV node. Lastly, the ventricular left and right conduction systems are detailed. These include the main trunk and their peripheral subdivisions with respective networks. Regarding the controversial existence of the left middle subdivision, it can exist in animal and human hearts. Nevertheless, an intermediate left septal network of specialized fibers seems to act as a functional equivalent of this subdivision. Copyright © 2012 Instituto Nacional de Cardiología Ignacio Chávez. Published by Masson Doyma México S.A. All rights reserved.

  19. Resolving an 80-yr-old controversy: the beginning of the modern era of renal physiology.

    Science.gov (United States)

    Jamison, Rex L

    2014-12-01

    Marcello Malpighi discovered the glomerulus that bears his name in the 17th century, but it was not until the middle of the 19th century, in 1842, that William Bowman in London published his studies of the histological structure of the glomerulus and proposed that urine formation begins with glomerular secretion. At nearly the same time in Marburg, Carl Ludwig, unaware of Bowman's findings, proposed that urine formation begins with glomerular filtration followed by tubule reabsorption. The controversy lasted 80 yr. Prominent investigators weighed in on both sides. Rudolph Heidenhain's findings in 1874 swung the pendulum toward Bowman's theory until Arthur Cushny published his book, The Secretion of Urine, in 1917, in which he found the evidence insufficient to prove either theory. In 1921, a young physician, Joseph Wearn, began his postresidency training in the laboratory of Alfred N. Richards. He read Cushny's book and learned how to expose the glomerulus of a living frog. Richards proposed that Wearn use that experimental preparation to inject epinephrine into the glomerulus. Wearn proposed a different experiment: instead of using injection, collect fluid from the glomerulus and analyze it. Richards agreed, and the landmark results of that experiment, published in 1924, settled the controversy. The modern era of renal physiology was born. Copyright © 2014 The American Physiological Society.

  20. Dynamics and Melting of Finite Plasma Crystals

    Science.gov (United States)

    Ludwig, Patrick; K"Ahlert, Hanno; Baumgartner, Henning; Thomsen, Hauke; Bonitz, Michael

    2009-11-01

    Interacting few-particle systems in external trapping potentials are of strong current interest since they allow to realize and control strong correlation and quantum effects [1]. Here, we present our recent results on the structural and thermodynamic properties of the crystal-like Wigner phase of complex plasma confined in a 3D harmonic potential. We discuss the linear response of the strongly correlated system to external excitations, which can be described in terms of normal modes [2]. By means of first-principle simulations the details of the melting phase transitions of these mesoscopic systems are systematically analysed with the melting temperatures being determined by a modified Lindemann parameter for the pair distance fluctuations [3]. The critical temperatures turn out to be utmost sensitive to finite size effects (i.e., the exact particle number), and form of the (screened) interaction potential.[4pt] [1] PhD Thesis, P. Ludwig, U Rostock (2008)[0pt] [2] C. Henning et al., J. Phys. A 42, 214023 (2009)[0pt] [3] B"oning et al., Phys. Rev. Lett. 100, 113401 (2008)

  1. Female pattern hair loss.

    Science.gov (United States)

    Herskovitz, Ingrid; Tosti, Antonella

    2013-10-01

    Female pattern hair loss (FPHL) also known as female androgenetic alopecia is a common condition afflicting millions of women that can be cosmetically disrupting. Prompt diagnosis and treatment are essential for obtaining optimal outcome. This review addresses the clinical presentation of female pattern hair loss, its differential diagnosis and treatment modalities. A) Diffuse thinning of the crown region with preservation of the frontal hairline (Ludwig's type) B) The "Christmas tree pattern" where the thinning is wider in the frontal scalp giving the alopecic area a triangular shaped figure resembling a christmas tree. C) Thinning associated with bitemporal recession (Hamilton type). Generally, FPHL is not associated with elevated androgens. Less commonly females with FPHL may have other skin or general signs of hyperandrogenism such as hirsutism, acne, irregular menses, infertility, galactorrhea and insulin resistance. The most common endocrinological abnormality associated with FPHL is polycystic ovarian syndrome (PCOS). The most important diseases to consider in the differential diagnosis of FPHL include Chronic Telogen Effluvium (CTE), Permanent Alopecia after Chemotherapy (PAC), Alopecia Areata Incognito (AAI) and Frontal Fibrosing Alopecia (FFA). This review describes criteria for distinguishing these conditions from FPHL. The only approved treatment for FPHL, which is 2% topical Minoxidil, should be applied at the dosage of 1ml twice day for a minimum period of 12 months. This review will discuss off-label alternative modalities of treatment including 5-alfa reductase inhibitors, antiandrogens, estrogens, prostaglandin analogs, lasers, light treatments and hair transplantation.

  2. Ultrasonography in the evaluation of tongue and mouth pathology

    International Nuclear Information System (INIS)

    Lee, Chan Wha; Chung, Tae Sub; Suh, Jung Ho; Kim, Dong Ik; Lee, Jong Tae; Hong, Won Pyo; Park, Hyung Sik

    1991-01-01

    The evaluation of the tongue and mouth floor using the CT scan can be limited due to dental artifacts. Because the therapeutic plan depends on the nature and the cancer staging of lesions, it is essential to obtain accurate evaluation of lesions. In this study are explored the of Ultrasonography for the evaluation of tongue and mouth floor pathology. We have obtained ultrasonograms in 20 patients who had benign and malignant lesions in the tongue and mouth floor. Comparative analysis was made on 15 patients who underwent both CT and ultrasonography. We used the bimanual compression technique and the phonation technique during real-time scanning. Out of 15 cases, six had tongue cancer, and seven of them had cancer of the mouth floor. The other cases included a ranula, a dermoid cyst, a Ludwig's angina, and abscess of salivary gland, and one care with stones of the submandibular gland. All the benign and malignant masses appeared hypoechoic. Even though the lesions of tongue and mouth floor could not be evaluated by CT scan due to dental artifacts and extremely small size in 5 cases, ultrasonogram using the bimanual compression technique demonstrated good localization of the lesion, and also was greatly helpful in visualizing the invasion of the surrounding structures. Ultrasonography of the tongue and mouth floor proved to be superior to the CT scan not only in delineating the size and extent of the primary lesion, but also in visualizing invasion of surrounding structures

  3. Heritage of the romantic philosophy in post-Linnaean botany Reichenbach's reception of Goethe's metamorphosis of plants as a methodological and philosophical framework.

    Science.gov (United States)

    Robin, Nicolas

    2011-01-01

    This paper demonstrates the importance of the reception and development of Goethe's metamorphosis of plants as a methodological and philosophical framework in the history of botanical theories. It proposes a focus on the textbooks written by the German botanist Ludwig Reichenbach and his first attempt to use Goethe's idea of metamorphosis of plants as fundamental to his natural system of plants published under the title 'Botany for Women', in German Botanik für Damen (1828). In this book, Reichenbach paid particular attention to Goethe's sensitive views on the essence of nature; he regarded Goethe's idea of metamorphosis in the plant kingdom as an ideal model to interpret connections of natural phenomena, in particular as a conceptual frame for a natural system. Furthermore, he aimed to develop the philosophical statement of the metamorphosis, in which he called for nature-philosophical conceptions in order to materialize his representation of plant "affinities," and of a kind of "ontogeny" of the whole plant kingdom. This paper demonstrates that, between speculative views and empirical attempts, the extent to which Reichenbach actually belonged to a new "school" of thought, which left its mark on the history and philosophy of botany.

  4. Boltzmann

    International Nuclear Information System (INIS)

    Lin, X.

    1991-01-01

    This paper reports the development of an object-oriented programming methodology for particle simulations. It is established on the [m reductionist] view that many physical phenomena cana be reduced to many-body problems. By doing the reduction, many seemly unrelated physical phenomena can be simulated in a systematic way and a high-level programming system can be constructed to facilitate the programming and the solution of the simulations. In the object-oriented particle simulation methodology, a hierarchy of abstract particles is defined to represent a variety of characteristics in physical system simulations. A simulation program is constructed from particles derived from the abstract particles. The object- oriented particle simulation methodology provides a unifying modeling and simulation framework for a variety of simulation applications with the use of particle methods. It allows easy composition of simulation programs from predefined software modules and facilitates software reusability. It greatly increase the productivity of simulation program constructions. Boltzmann (after Ludwig Boltzmann, 1844-1906) is a prototype programming system in the object-oriented particle simulation methodology. Boltzmann is implemented in C++ and the X Window System. It contains a library of data types and functions that support simulations in particle methods. Moreover, it provides a visualization window to support friendly user-computer interaction. Examples of the application of the Boltzmann programming system are presented. The effectiveness of the object-oriented particle simulation methodology is demonstrated. A user's manual is included in the appendix

  5. Two New Long-period Hot Subdwarf Binaries with Dwarf Companions

    Science.gov (United States)

    Barlow, Brad N.; Liss, Sandra E.; Wade, Richard A.; Green, Elizabeth M.

    2013-07-01

    Hot subdwarf stars with F-K main sequence binary companions have been known for decades, but the first orbital periods for such systems were published just recently. Current observations suggest that most have long periods, on the order of years, and that some are or once were hierarchical triple systems. As part of a survey with the Hobby-Eberly Telescope, we have been monitoring the radial velocities of several composite-spectra binaries since 2005 in order to determine their periods, velocities, and eccentricities. Here we present observations and orbital solutions for two of these systems, PG 1449+653 and PG 1701+359. Similar to the other sdB+F/G/K binaries with solved orbits, their periods are long, 909 and 734 days, respectively, and pose a challenge to current binary population synthesis models of hot subdwarf stars. Intrigued by their relatively large systemic velocities, we also present a kinematical analysis of both targets and find that neither is likely a member of the Galactic thin disk. Based on observations obtained with the Hobby-Eberly Telescope, which is a joint project of the University of Texas at Austin, the Pennsylvania State University, Stanford University, Ludwig-Maximilians-Universität München, and Georg-August-Universität Göttingen.

  6. Parsec-scale Variations in the 7Li I/6Li I Isotope Ratio Toward IC 348 and the Perseus OB 2 Association

    Science.gov (United States)

    Knauth, D. C.; Taylor, C. J.; Ritchey, A. M.; Federman, S. R.; Lambert, D. L.

    2017-01-01

    Measurements of the lithium isotopic ratio in the diffuse interstellar medium from high-resolution spectra of the Li I λ6708 resonance doublet have now been reported for a number of lines of sight. The majority of the results for the 7Li/6Li ratio are similar to the solar system ratio of 12.2, but the line of sight toward o Per, a star near the star-forming region IC 348, gave a ratio of about two, the expected value for gas exposed to spallation and fusion reactions driven by cosmic rays. To examine the association of IC 348 with cosmic rays more closely, we measured the lithium isotopic ratio for lines of sight to three stars within a few parsecs of o Per. One star, HD 281159, has 7Li/6Li ≃ 2 confirming production by cosmic rays. The lithium isotopic ratio toward o Per and HD 281159 together with published analyses of the chemistry of interstellar diatomic molecules suggest that the superbubble surrounding IC 348 is the source of the cosmic rays. Based on observations obtained with the Hobby-Eberly Telescope, which is a joint project of the University of Texas at Austin, the Pennsylvania State University, Ludwig-Maximilians-Universität München, and Georg-August-Universität Göttingen.

  7. The Masses and Evolutionary State of the Stars in the Dwarf Nova SS Cygni

    Science.gov (United States)

    Bitner, Martin A.; Robinson, Edward L.; Behr, Bradford B.

    2007-06-01

    The dwarf nova SS Cygni is a close binary star consisting of a K star transferring mass to a white dwarf by way of an accretion disk. We have obtained new spectroscopic observations of SS Cyg. Fits of synthetic spectra for Roche lobe-filling stars to the absorption-line spectrum of the K star yield the amplitude of the K star's radial velocity curve and the mass ratio, KK=162.5+/-1.0 km s-1 and q=MK/MWD=0.685+/-0.015. The fits also show that the accretion disk and white dwarf contribute a fraction f=0.535+/-0.075 of the total flux at 5500 Å. Taking the weighted average of our results with previously published results obtained using similar techniques, we find =163.7+/-0.7 km s-1 and =0.683+/-0.012. The orbital light curve of SS Cyg shows an ellipsoidal variation diluted by light from the disk and white dwarf. From an analysis of the ellipsoidal variations, we limit the orbital inclination to the range 45degAustin, the Pennsylvania State University, Stanford University, Ludwig-Maximilians-Universität München, and Georg-August-Universität Göttingen.

  8. Vertex Accentuation in Female Pattern Hair Loss in Asians

    Directory of Open Access Journals (Sweden)

    Chavalit Supsrisunjai

    2016-05-01

    Full Text Available Background: The most common cause of hair loss seen in women is female pattern hair loss (FPHL, also known as female androgenetic alopecia. It affects the central part of the scalp, but spares the frontal hairline. Frontal accentuation was also described by Olsen. In Asian women, vertex thinning patterns are frequently developed, but there has been no report about vertex thinning pattern in female pattern hair loss. Objective: To find prevalence of vertex accentuation in female pattern hair loss (FPHL in Asian women. Methods: Scalp hair counting (n/cm2 were measured at 3 different areas; vertex, mid scalp and frontal area respectively by digital dermoscope (Dino digital AM-413T. Visual counting and photography were performed. Outcomes were evaluated by gross appearance of vertex thinning and/or hair density <120 /cm2 in any of 3 areas. Results: 143 patients were evaluated. Mean age was 45.54 years. Of the hair loss type, 36.4% were mid-scalp, 33.6% were vertex accentuation and 30.1% were frontal accentuation, respectively. Age was not significantly different among the 3 types of hair loss (P- value 0.859. Conclusion: Although the most common female pattern hair loss type is diffuse type (Ludwig type, vertex accentuation pattern is the second most common pattern in this study. This study is the first to mention “Vertex accentuation” to be another pattern for FPHL.

  9. [The influence of music on pictorial expression of young women--a comparative study of different music styles].

    Science.gov (United States)

    Schiltz, L; Maugendre, M; Brytek-Matera, A

    2010-01-01

    Questing one's personal identity and developing a coherent representation of oneself, the other and the world are major tasks in adolescence. Research showed that a satisfactory resolution of the crisis of adolescence can be favoured by psychological counselling based on artistic mediations. The objective of this study consisted in exploring the effect of music on the pictorial expression of a non clinical sample of female adolescents (N=157) aged from 17 to 28 years. We analysed free drawings realised by the test group with the help of a rating scale constructed in a phenomenological and structural perspective (Schiltz, 2006). The adolescents painted under musical induction. We proposed three different styles of music, i.e. baroque music (Georg Friedrich Händel and Johann Sebastian Bach), classical music (Wolfgang Amadeus Mozart and Ludwig van Beethoven) and polish ethnical music (Kapela ze Wsi Warszawa-Warsaw Village Band). By using non parametric inferential and multi dimensional statistics, we could show that structural characteristics of music styles lead to differences in formal and content variables on the rating scales for the pictures. The results of our exploratory study open some tracks for future research. It would be pertinent to enlarge the population to other categories of age and to investigate the influence of gender.

  10. e-Learning strategies in occupational legal medicine based on problem solving through "CASUS" system.

    Science.gov (United States)

    Martínez-Jarreta, B; Monsó, E; Gascón, S; Casalod, Y; Abecia, E; Kolb, S; Reichert, J; Radon, K

    2009-04-01

    The use of online teaching tools facilitate the incorporation of self-learning methods. With a view to encouraging convergence in teaching tools and methods in Occupational Legal Medicine, an initiative was set up within the classes of Legal and Forensic Medicine at Saragossa University, as part of the EU funded NetWoRM project, which has been led since 1999 by Ludwig-Maximilians-Universität in Munich (Germany). The interest of medical students in Occupational Legal Medicine has so far been low and in addition different aspects complicate the teaching of Occupational Legal Medicine at medical schools: One reason for the low interest is the limited availability of bedside teaching, one of the students' most favourite and effective way to learn. The reason for that is that most medical schools with occupational departments only have outpatient clinics. "Interesting" patients who be need for educational purposes are therefore only available for a limited part of the day. However, in order to recognize and prevent occupational disorders each medical student and physician needs profound clinical knowledge in Occupational Legal Medicine. This project has proven to be highly efficient in permitting the creation and validation of teaching tools which cover and improve the traditional training of the Occupational Legal Medicine programme imparted in the degree of Medicine.

  11. Rojas Zorrilla ante la crítica romántica

    Directory of Open Access Journals (Sweden)

    Pedraza Jiménez, Felipe B

    2007-06-01

    Full Text Available To Romantic Criticism, Rojas Zorrilla’s fame becomed obscure by the figure of his contemporary, friend and collaborator, Pedro Calderón de la Barca. This logical situation is clearly evident in the great german critics: Rojas Zorrilla is scarcely mentioned by the Schlegel brothers. To other historians he occupied a secondary place and the only exception was Johann Ludwig Tieck, who exalted his works even above Calderón masterpieces. It can be affirmed that Rojas Zorrilla reception was irregular. If we examine Musso Valiente’s library, Agustín Durán’s Discurso, and the romantic period editions, we will find some interest in his figure and that it was situated in a secondary place in relation to our great theater. It seems clear that Martínez de la Rosa and Alberto Lista were the critics who pay more attention to him. Martínez de la Rosa established an approach based in the neoclassic topics about our writer, meanwhile Alberto Lista developed a closer and original reading, specially centered in the poet’s tragic dimension and elements that, from his point of view, anticipated romantic Aesthetics. Rojas Zorrilla inclusion in romantic Literary Histories, and his edition in the «Biblioteca de Autores Españoles», prepared by Mesonero Romanos, make him enter the canon among the «six great stars» in Spanish Golden Age Theater.Para la crítica romántica, la fama de Rojas Zorrilla quedó oscurecida, de forma perfectamente lógica, por la de su coetáneo, amigo y colaborador don Pedro Calderón de la Barca. Esta situación es muy patente en los grandes críticos alemanes. Los hermanos Schlegel apenas citan a nuestro dramaturgo. Otros historiadores le conceden un lugar secundario, con la excepción de Johann Ludwig Tieck, que lo exaltó incluso por encima del autor de La vida es sueño. La recepción de su obra en España fue irregular. Del análisis de la biblioteca y escritos de Musso Valiente, del discurso de Agustín Durán, de las

  12. A Novel Large-scale Mentoring Program for Medical Students based on a Quantitative and Qualitative Needs Analysis [Aufbau eines innovativen Mentorenprogramms für eine große Zahl Medizinstudierender nach quantitativer und qualitativer Bedarfsanalyse

    Directory of Open Access Journals (Sweden)

    von der Borch, Philip

    2011-05-01

    Full Text Available [english] Purpose: Mentoring plays an important role in students' performance and career. The authors of this study assessed the need for mentoring among medical students and established a novel large-scale mentoring program at Ludwig-Maximilians-University (LMU Munich School of Medicine.Methods: Needs assessment was conducted using a survey distributed to all students at the medical school (n=578 of 4,109 students, return rate 14.1%. In addition, the authors held focus groups with selected medical students (n=24 and faculty physicians (n=22. All students signing up for the individual mentoring completed a survey addressing their expectations (n=534.Results: Needs assessment revealed that 83% of medical students expressed overall satisfaction with the teaching at LMU. In contrast, only 36.5% were satisfied with how the faculty supports their individual professional development and 86% of students voiced a desire for more personal and professional support. When asked to define the role of a mentor, 55.6% "very much" wanted their mentors to act as counselors, arrange contacts for them (36.4%, and provide ideas for professional development (28.1%. Topics that future mentees "very much" wished to discuss included research (56.6%, final year electives (55.8% and experiences abroad (45.5%.Conclusions: Based on the strong desire for mentoring among medical students, the authors developed a novel two-tiered system that introduces one-to-one mentoring for students in their clinical years and offers society-based peer mentoring for pre-clinical students. One year after launching the program, more than 300 clinical students had experienced one-to-one mentoring and 1,503 students and physicians were involved in peer mentoring societies.[german] Hintergrund: Mentoring ist eine wichtige Stütze in der Karriere von Studierenden. In der vorliegenden Untersuchung dokumentieren wir den Mentoring-Bedarf der Medizinstudierenden an der Medizinischen Fakultät der

  13. HANNES MEYER Y LA ESCUELA FEDERAL ADGB: LA SERIE COMO ESTRATEGIA FORMAL / HANNES MEYER AND THE ADGB TRADE UNION SCHOOL: SERIES AS A FORMAL STRATEGY

    Directory of Open Access Journals (Sweden)

    Víctor Larripa Artieda

    2017-11-01

    Full Text Available RESUMEN Hannes Meyer fue uno de los arquitectos más comprometidos con las ideas del ala radical del racionalismo, que él mismo y otros grandes arquitectos, como Mart Stam, Hans Wittwer, Karel Teige, Ludwig Hilberseimer o Ernst May, desarrollaron durante la década de los años veinte. Su voluntad de desvincular la arquitectura del “high–art” burgués y de todo simbolismo propio del pasado, de producir construcciones de carácter objetivo y social, quedó patente en proyectos y obras firmadas por todos ellos: en el caso de Meyer, probablemente, la construcción que mejor expresa tales postulados y aquel nuevo modo de hacer arquitectura sea la Escuela Federal ADGB; construida en Bernau entre 1928 y 1930. El presente artículo estudia la citada obra, a la luz del ideario arquitectónico y social de arquitecto suizo, y trata de exponer la estrategia que se encuentra detrás de su formalización: la serie. En efecto, a partir de este mecanismo de proyecto, basado en la repetición o reproducción casi infinita de sistemas constructivos o de unidades del programa–o de ambas al mismo tiempo–aquellos arquitectos descubrieron un nuevo modo de generar la forma arquitectónica, moderno y muy poco explorado hasta entonces. Una vía donde valores como la horizontalidad, la ausencia de centro o jerarquía, la igualdad y la objetividad se erigían como el nuevo relato de la arquitectura. SUMMARY Hannes Meyer was one of the most committed architects to the ideas of the radical wing of rationalism, which he himself and other great architects, such as Mart Stam, Hans Wittwer, Karel Teige, Ludwig Hilberseimer and Ernst May, developed during the twenties. Their desire to unshackle architecture from bourgeois “high art” and from all symbolism from the past, to produce constructions of an objective and social nature, was made patent in the designs and works signed by all of them. With regard to Meyer, the construction which best expresses these

  14. Linguagens manifestadas por (futuros professores que ensinam matemática em tarefas de multiplicação e divisão

    Directory of Open Access Journals (Sweden)

    Michele Regiane Dias Veronez

    2015-11-01

    Full Text Available By assuming that different languages permeate tasks developed in Mathematics classrooms and that these languages may signal the (lack of knowledge of agents who participate in them, we bring to discussion in this paper, according to Ludwig Wittgenstein’s premises (2009 about language, how students in an undergraduate Education course deal with multiplication and division operations. Supported by Wittgenstein’s notions of language games, we seek to identify the games which are present in actions of these students as they solve the tasks proposed, and the family resemblances saved among them. Therefore, we analyzed productions of students (scripts in natural language, scripts in mathematical language, scripts in pictorial language, as well as transcripts of recordings of their involvement with the tasks. On one hand, the analysis shows that, despite the occurrence of a variety of languages, the mathematical language seems to validate mathematical knowledge. On the other hand, in students’ productions, the languages keep, in general, family resemblances, from a game to another, to a third game, or within own the game. Despite such similarities, inconsistencies related to the conceptual development of students’ multiplication and division, often sustained in routine expressions in the classroom, lead us to infer that there is a lack of epistemological depth related to these operations, and therefore to the decimal numeration system. Ao assumir que diferentes linguagens permeiam as tarefas desenvolvidas nas salas de aula de Matemática e podem sinalizar os (desconhecimentos dos agentes que delas participam, trazemos para discussão, neste artigo, segundo os pressupostos de Ludwig Wittgenstein (2009 a respeito da linguagem, como alunas de um curso de Pedagogia lidam com operações de multiplicação e divisão. Amparados nas noções wittgensteinianas de jogos de linguagem, buscamos identificar os jogos que se encontram presentes nas a

  15. De las normas como compromisos prácticos y de la locura como incumplimiento de tales compromisos

    Directory of Open Access Journals (Sweden)

    Quintana Paz, Miguel Ángel

    2006-06-01

    Full Text Available From a post-metaphysical point of view, and making use of arguments provided mainly by Ludwig Wittgenstein, I will try to endorse the following thesis in this paper: that norms in general receive their normative character only from the responsibility that is attributed to each agent when they act in a social context. This context is full, thus, of normative commitments as its sine qua non. Since (in post-metaphysics these commitments cannot co-respond to any other (metaphysical instance apart from the social agents, we have here a kind of commitments very near to what traditionally has been conceived as an ethical-political notion of responsibility. A rule does not request us to fulfil it, but we humans do request others to do so; if a rule has not been obeyed, we ask for accounts of its unfulfillment, or apply different kinds of measures against the violator. In fact, if someone fails to fulfil an important rule, it is even possible to separate them from our life in society, pronouncing them to be absolutely «evil» or persistently «mad». When we realize in such a way that the power of rules dwells only on this sort of mutual responsibility, a new rule (a rule of tolerance can become reasonable for us: the rule of tolerating the possibility of other commitments with different rules in alien contexts that have generated other responsibilities different from ours.

    Desde un punto de vista postmetafísico y a partir de los argumentos que nos proporciona (fundamentalmente un autor como Ludwig Wittgenstein, trataremos de defender la tesis de que las normas en general cobran su carácter normativo de la responsabilidad que se atribuye a cada agente cuando, al actuar en sociedad, se liga a los compromisos que sostienen la posibilidad de que esa acción sea común. Esos compromisos, ya que (en la postmetafísica no pueden responder ante una instancia ajena a los agentes sociales (metafísica, habrán de tener el cariz práctico (

  16. Os espaços cervicais profundos e seu interesse nas infecções da região Deep neck spaces and their interest in cervical infections

    Directory of Open Access Journals (Sweden)

    M.D. Durazzo

    1997-06-01

    Full Text Available As infecções dos espaços cervicais profundos, embora raras, associam-se a alta morbi-mortalidade. A abordagem cirúrgica faz-se necessária na maioria dos casos e se baseia no conhecimento da complexa anatomia das fáscias cervicais e dos espaços cervicais profundos. OBJETIVO. Apresentar considerações anatômicas de interesse prático sobre fáscias e espaços do pescoço, sua conceituação e nomenclatura, relatando, a título de exemplo, quatro casos de infecções dos espaços cervicais profundos. MATERIAL E MÉTODO. São apresentados um caso de angina de Ludwig complicada com mediastinite, pericardite, pneumonia, empiema pleural, fístula esofágica e choque séptico, um caso de abscesso cervical espontâneo em paciente diabético, um caso de abscesso de loja submandibular e um caso de abscesso parafaríngeo iniciado após manipulação dentária. Nos quatro casos, a documentação imagenológica é rica e, em dois deles, evidencia o comprometimento de mais de um espaço profundo do pescoço. CONCLUSÕES. A literatura enfatiza morbidade e mortalidade elevadas, etiologia diversificada (infecções dentárias, uso de drogas endovenosas, infecções do trato aerodigestivo alto e outras, a necessidade de traqueostomia em cerca de 50% dos casos e o emprego da terapêutica combinada (antibioticoterapia e abordagem cirúrgica do pescoço. Os métodos imagenológicos, como a tomografia computadorizada, são imprescindíveis no estudo de infecções dos espaços profundos do pescoço, tanto para a avaliação do sítio e extensão da afecção, como para o planejamento terapêutico.BACKGROUND. Although rare, deep neck space infections are associated with high morbidity and mortality rates. The surgical approach is necessary in the majority of the cases, and the surgeon must know the complex anatomy of the cervical fasciae and deep neck spaces. PURPOSE. The anatomy of the cervical fasciae and deep neck spaces is reviewed. As an illustration, a

  17. Treatment of respiratory failure in COPD

    Directory of Open Access Journals (Sweden)

    Stephan Budweiser

    2008-12-01

    Full Text Available Stephan Budweiser1, Rudolf A Jörres2, Michael Pfeifer1,31Center for Pneumology, Hospital Donaustauf, Donaustauf, Germany; 2Institute and Outpatient Clinic for Occupational, Social and Environmental Medicine, Ludwig-Maximilians-University, Munich, Germany; 3Department of Internal Medicine II, Division of Respirology, University of Regensburg, Regensburg, GermanyAbstract: Patients with advanced COPD and acute or chronic respiratory failure are at high risk for death. Beyond pharmacological treatment, supplemental oxygen and mechanical ventilation are major treatment options. This review describes the physiological concepts underlying respiratory failure and its therapy, as well as important treatment outcomes. The rationale for the controlled supply of oxygen in acute hypoxic respiratory failure is undisputed. There is also a clear survival benefit from long-term oxygen therapy in patients with chronic hypoxia, while in mild, nocturnal, or exercise-induced hypoxemia such long-term benefits appear questionable. Furthermore, much evidence supports the use of non-invasive positive pressure ventilation in acute hypercapnic respiratory failure. It application reduces intubation and mortality rates, and the duration of intensive care unit or hospital stays, particularly in the presence of mild to moderate respiratory acidosis. COPD with chronic hypercapnic respiratory failure became a major indication for domiciliary mechanical ventilation, based on pathophysiological reasoning and on data regarding symptoms and quality of life. Still, however, its relevance for long-term survival has to be substantiated in prospective controlled studies. Such studies might preferentially recruit patients with repeated hypercapnic decompensation or a high risk for death, while ensuring effective ventilation and the patients’ adherence to therapy.Keywords: respiratory failure, COPD, mechanical ventilation, non-invasive ventilation long-term oxygen therapy, chronic

  18. A wind proxy based on migrating dunes at the Baltic coast: statistical analysis of the link between wind conditions and sand movement

    Science.gov (United States)

    Bierstedt, Svenja E.; Hünicke, Birgit; Zorita, Eduardo; Ludwig, Juliane

    2017-07-01

    We statistically analyse the relationship between the structure of migrating dunes in the southern Baltic and the driving wind conditions over the past 26 years, with the long-term aim of using migrating dunes as a proxy for past wind conditions at an interannual resolution. The present analysis is based on the dune record derived from geo-radar measurements by Ludwig et al. (2017). The dune system is located at the Baltic Sea coast of Poland and is migrating from west to east along the coast. The dunes present layers with different thicknesses that can be assigned to absolute dates at interannual timescales and put in relation to seasonal wind conditions. To statistically analyse this record and calibrate it as a wind proxy, we used a gridded regional meteorological reanalysis data set (coastDat2) covering recent decades. The identified link between the dune annual layers and wind conditions was additionally supported by the co-variability between dune layers and observed sea level variations in the southern Baltic Sea. We include precipitation and temperature into our analysis, in addition to wind, to learn more about the dependency between these three atmospheric factors and their common influence on the dune system. We set up a statistical linear model based on the correlation between the frequency of days with specific wind conditions in a given season and dune migration velocities derived for that season. To some extent, the dune records can be seen as analogous to tree-ring width records, and hence we use a proxy validation method usually applied in dendrochronology, cross-validation with the leave-one-out method, when the observational record is short. The revealed correlations between the wind record from the reanalysis and the wind record derived from the dune structure is in the range between 0.28 and 0.63, yielding similar statistical validation skill as dendroclimatological records.

  19. Model atmospheres for M (sub)dwarf stars. 1: The base model grid

    Science.gov (United States)

    Allard, France; Hauschildt, Peter H.

    1995-01-01

    We have calculated a grid of more than 700 model atmospheres valid for a wide range of parameters encompassing the coolest known M dwarfs, M subdwarfs, and brown dwarf candidates: 1500 less than or equal to T(sub eff) less than or equal to 4000 K, 3.5 less than or equal to log g less than or equal to 5.5, and -4.0 less than or equal to (M/H) less than or equal to +0.5. Our equation of state includes 105 molecules and up to 27 ionization stages of 39 elements. In the calculations of the base grid of model atmospheres presented here, we include over 300 molecular bands of four molecules (TiO, VO, CaH, FeH) in the JOLA approximation, the water opacity of Ludwig (1971), collision-induced opacities, b-f and f-f atomic processes, as well as about 2 million spectral lines selected from a list with more than 42 million atomic and 24 million molecular (H2, CH, NH, OH, MgH, SiH, C2, CN, CO, SiO) lines. High-resolution synthetic spectra are obtained using an opacity sampling method. The model atmospheres and spectra are calculated with the generalized stellar atmosphere code PHOENIX, assuming LTE, plane-parallel geometry, energy (radiative plus convective) conservation, and hydrostatic equilibrium. The model spectra give close agreement with observations of M dwarfs across a wide spectral range from the blue to the near-IR, with one notable exception: the fit to the water bands. We discuss several practical applications of our model grid, e.g., broadband colors derived from the synthetic spectra. In light of current efforts to identify genuine brown dwarfs, we also show how low-resolution spectra of cool dwarfs vary with surface gravity, and how the high-regulation line profile of the Li I resonance doublet depends on the Li abundance.

  20. Psychiatric diagnoses are not mental processes: Wittgenstein on conceptual confusion.

    Science.gov (United States)

    Rosenman, Stephen; Nasti, Julian

    2012-11-01

    Empirical explanation and treatment repeatedly fail for psychiatric diagnoses. Diagnosis is mired in conceptual confusion that is illuminated by Ludwig Wittgenstein's later critique of philosophy (Philosophical Investigations). This paper examines conceptual confusions in the foundation of psychiatric diagnosis from some of Wittgenstein's important critical viewpoints. Diagnostic terms are words whose meanings are given by usages not definitions. Diagnoses, by Wittgenstein's analogy with 'games', have various and evolving usages that are connected by family relationships, and no essence or core phenomenon connects them. Their usages will change according to the demands and contexts in which they are employed. Diagnoses, like many psychological terms, such as 'reading' or 'understanding', are concepts that refer not to fixed behavioural or mental states but to complex apprehensions of the relationship of a variety of behavioural phenomena with the world. A diagnosis is a sort of concept that cannot be located in or explained by a mental process. A diagnosis is an exercise in language and its usage changes according to the context and the needs it addresses. Diagnoses have important uses but they are irreducibly heterogeneous and cannot be identified with or connected to particular mental processes or even with a unity of phenomena that can be addressed empirically. This makes understandable not only the repeated failure of empirical science to replicate or illuminate genetic, neurophysiologic, psychic or social processes underlying diagnoses but also the emptiness of a succession of explanatory theories and treatment effects that cannot be repeated or stubbornly regress to the mean. Attempts to fix the meanings of diagnoses to allow empirical explanation will and should fail as there is no foundation on which a fixed meaning can be built and it can only be done at the cost of the relevance and usefulness of diagnosis.

  1. Bavarian liquid hydrogen bus demonstration project - safety, licensing and acceptability aspects

    Energy Technology Data Exchange (ETDEWEB)

    Wurster, R.; Knorr, H.; Pruemm, W.

    1999-07-01

    A regular 12 m city bus of the MAN SL 202 type with an internal combustion engine adapted to hydrogen operation and auxiliary gasoline operation was demonstrated in the Bavarian cities of Erlangen and Munich between April 1996 and August 1998. Three bus operators, Erlanger Stadtwerke, Stadtwerke Muenchen and Autobus Oberbayern were testing the bus in three different operating schemes. In order to be able to perform this worldwide first public demonstration of a liquid hydrogen (LH{sub 2}) city bus in regular service, several requirements with respect to safety, licensing, training and acceptability had to be fulfilled. These activities were focusing mainly on the hydrogen specific issues such as (a) integration of onboard LH{sub 2} storage vessels, piping and instrumentation, (b) implementation of storage and refueling infrastructure in the operators' yards, (c) adaptation of the maintenance garages, (d) training of operating and maintenance personnel. During phase II of the demonstration activity a poll was performed on passengers traveling onboard the hydrogen-powered city bus in order to determined the level of acceptance among the users of the bus. The bus was designed and manufactured by MAN Nutzfahrzeuge Aktiengesellschaft. The cryogenic fuel storage and the refueling equipment were designed and manufactured by Linde AG. The realization of the hardware was financially supported by the European Commission (EC) within the Euro-Quebec Hydro-Hydrogen Pilot Project. The demonstration phase was financially supported by EC and the Bavarian State Government. Ludwig-Boelkow-Systemtechnik performed project monitoring for both funding organizations. The presentation will summarize the most important results of this demonstration phase and will address the measures undertaken in order to get the bus, the refueling infrastructure and the maintenance and operating procedures approved by the relevant authorities.

  2. Zagadnienie tożsamości bytu w filozofii buddyjskiej

    Directory of Open Access Journals (Sweden)

    Krzysztof JAKUBCZAK

    2015-06-01

    Full Text Available The Buddhist philosophical school of Madhyamaka is famous for its statement that things do not have their own inherent nature, essence or self‑nature (svabhāva. As a result, it is said that there is no objective foundation of the identity of things. Thus, the identity of things is not grounded in things themselves but is solely imputed and externally imposed on them. Things are what they are only for us, whereas for themselves, or from their ‘own side’ they are empty (śūnya. That is why Madhyamaka philosophy is often compared to the philosophical conceptions inspired by a linguistic reflection (from Ludwig Wittgenstein to Jacques Derrida which defines the problem of identity in terms of cognitive subjectivism and constructivism. Starting the analysis from the Abhidharma Buddhist tradition I will show that this reading of Madhyamaka view is too narrow. I will demonstrate that it is a result of an assumption, shared by Parmenides and Plato and wrongly ascribed to this Buddhist school, that the identity of being must be grounded in the self‑existing, self‑defined and (relatively permanent ontological foundation. This tacit assumption, if rejected, makes any identity a completely subjective and relative construct. The point I am going to argue for, however, is that the Madhyamaka school sticks to an alternative understanding of objectivity; the foundation of all things is nothing but pure relation that precedes, in the ontological sense, all co‑related elements (i.e. things. Therefore, the question comes up: how being‑in‑relationship or ‘relationality’ may be the foundation of identity and what kind of identity it endows. I will try to answer these questions.

  3. Triangularity effects on the collisional diffusion for elliptic tokamak plasma

    International Nuclear Information System (INIS)

    Martin, P.; Castro, E.

    2007-01-01

    In this conference the effect of ellipticity and triangularity will be analyzed for axisymmetric tokamak in the collisional regime. Analytic forms for the magnetic field cross sections are taken from those derived recently by other authors [1,2]. Analytical results can be obtained in elliptic plasmas with triangularity by using an special system of tokamak coordinates recently published [3-5]. Our results show that triangularities smaller than 0.6, increases confinement for ellipticities in the range 1.2 to 2. This behavior happens for negative and positive triangularities; however this effect is stronger for positive than for negative triangularities. The maximum diffusion velocity is not obtained for zero triangularity, but for small negative triangularities. Ellipticity is also very important in confinement, but the effect of triangularity seems to be more important. High electric inductive field increases confinement, though this field is difficult to modify once the tokamak has been built. The analytic form of the current produced by this field is like that of a weak Ware pinch with an additional factor, which weakens the effect by an order of magnitude. The dependence of the triangularity effect with the Shafranov shift is also analyzed. References 1. - L. L. Lao, S. P. Hirshman, and R. M. Wieland, Phys. Fluids 24, 1431 (1981) 2. - G. O. Ludwig, Plasma Physics Controlled Fusion 37, 633 (1995) 3. - P. Martin, Phys. Plasmas 7, 2915 (2000) 4. - P. Martin, M. G. Haines and E. Castro, Phys. Plasmas 12, 082506 (2005) 5. - P. Martin, E. Castro and M. G. Haines, Phys. Plasmas 12, 102505 (2005)

  4. Vinflunine in the treatment of bladder cancer

    Directory of Open Access Journals (Sweden)

    Mark Bachner

    2008-11-01

    Full Text Available Mark Bachner, Maria De Santis3rd Medical Department – Center for Oncology and Hematology, Kaiser Franz Josef-Spital der Stadt Wien, and Ludwig Boltzmann-Institute for Applied Cancer Research Vienna (LBI-ACR VIEnna, Cluster Translational Oncology, Kaiser Franz Josef-Spital der Stadt Wien, and Applied Cancer Research – Institution for Translational Research Vienna (ACR-ITR VIEnna/CEADDP, Vienna, AustriaAbstract: Vinflunine (VFL is a third-generation bifluorinated semi-synthetic vinca alkaloid obtained by superacidic chemistry from its parent compound, vinorelbine. As with the other vinca alkaloids, the main antineoplastic effects of VFL arise from its interaction with tubulin, the major component of microtubules in mitotic spindles. In contrast to other vinca alkaloids, VFL shows some distinctive properties in terms of tubulin binding, possibly explaining its superior antitumor activity in vitro and in vivo compared with vinorelbine as well as its excellent safety profile. In transitional cell carcinoma (TCC, two single-agent phase II trials were performed testing VFL in platinum-pretreated patients, showing moderate response rates and promising disease control rates. Therefore, the first phase III trial in modern times for second-line TCC of the urothelium was designed in order to further investigate the activity of VFL. First results were presented at the 2008 ASCO conference. VFL appears to be a possible treatment option for patients with TCC progressing after first-line platinum-containing chemotherapy.Keywords: vinflunine, transitional cell carcinoma (TCC of the bladder, bladder cancer, chemotherapy, second-line chemotherapy

  5. Language games: Christian fundamentalism and the science curriculum

    Science.gov (United States)

    Freund, Cheryl J.

    Eighty years after the Scope's Trial, the debate over evolution in the public school curriculum is alive and well. Historically, Christian fundamentalists, the chief opponents of evolution in the public schools, have used the court system to force policymakers, to adopt their ideology regarding evolution in the science curriculum. However, in recent decades their strategy has shifted from the courts to the local level, where they pressure teachers and school boards to include "alternate theories" and the alleged "flaws" and "inconsistencies" of evolution in the science curriculum. The purpose of this content analysis study was to answer the question: How do Christian fundamentalists employ rhetorical strategies to influence the science curriculum? The rhetorical content of several public legal and media documents resulting from a lawsuit filed against the Athens Public Schools by the American Center of Law and Justice were analyzed for the types of rhetorical strategies employed by the participants engaged in the scientific, legal, and public discourse communities. The study employed an analytical schema based on Ludwig Wittgenstein's theory of language games, Lawrence Prelli's theory of discourse communities, and Michael Apple's notion of constitutive and preference rules. Ultimately, this study revealed that adroit use of the constitutive and preference rules of the legal and public discourse communities allowed the school district to reframe the creation-evolution debate, thereby avoiding a public spectacle and ameliorating the power of creationist language to affect change in the science curriculum. In addition, the study reinforced the assertion that speakers enjoy the most persuasive power when they attend to the preference rules of the public discourse community.

  6. Genetic effects on information processing speed are moderated by age--converging results from three samples.

    Science.gov (United States)

    Ising, M; Mather, K A; Zimmermann, P; Brückl, T; Höhne, N; Heck, A; Schenk, L A; Rujescu, D; Armstrong, N J; Sachdev, P S; Reppermund, S

    2014-06-01

    Information processing is a cognitive trait forming the basis of complex abilities like executive function. The Trail Making Test (TMT) is a well-established test of information processing with moderate to high heritability. Age of the individual also plays an important role. A number of genetic association studies with the TMT have been performed, which, however, did not consider age as a moderating factor. We report the results of genome-wide association studies (GWASs) on age-independent and age-dependent TMT performance in two population-representative community samples (Munich Antidepressant Response Signature, MARS: N1 = 540; Ludwig Maximilians University, LMU: N2 = 350). Age-dependent genome-wide findings were then evaluated in a third sample of healthy elderly subjects (Sydney Memory and Ageing Study, Sydney MAS: N3 = 448). While a meta-analysis on the GWAS findings did not reveal age-independent TMT associations withstanding correction for multiple testing, we found a genome-wide significant age-moderated effect between variants in the DSG1 gene region and TMT-A performance predominantly reflecting visual processing speed (rs2199301, P(meta-analysis) = 1.3 × 10(-7)). The direction of the interaction suggests for the minor allele a beneficial effect in younger adults turning into a detrimental effect in older adults. The detrimental effect of the missense single nucleotide polymorphism rs1426310 within the same DSG1 gene region could be replicated in Sydney MAS participants aged 70-79, but not in those aged 80 years and older, presumably a result of survivor bias. Our findings demonstrate opposing effects of DSG1 variants on information processing speed depending on age, which might be related to the complex processes that DSG1 is involved with, including cell adhesion and apoptosis. © 2014 John Wiley & Sons Ltd and International Behavioural and Neural Genetics Society.

  7. An Augmented Reality magic mirror as additive teaching device for gross anatomy.

    Science.gov (United States)

    Kugelmann, Daniela; Stratmann, Leonard; Nühlen, Nils; Bork, Felix; Hoffmann, Saskia; Samarbarksh, Golbarg; Pferschy, Anna; von der Heide, Anna Maria; Eimannsberger, Andreas; Fallavollita, Pascal; Navab, Nassir; Waschke, Jens

    2018-01-01

    When preparing young medical students for clinical activity, it is indispensable to acquaint them with anatomical section images which enable them to use the clinical application of imaging methods. A new Augmented Reality Magic Mirror (AR MM) system, which provides the advantage of a novel, interactive learning tool in addition to a regular dissection course, was therefore tested and evaluated by 880 first-year medical students as part of the macroscopic anatomy course in 2015/16 at Ludwig-Maximilians-Universität (LMU) in Munich. The system consists of an RGB-D sensor as a real-time tracking device, which enables the system to link a deposited section image to the projection of the user's body, as well as a large display mimicking a real-world physical mirror. Using gesture input, the users have the ability to interactively explore radiological images in different anatomical intersection planes. We designed a tutorial during which students worked with the system in groups of about 12 and evaluated the results. Subsequently, each participant was asked to assess the system's value by filling out a Likert-scale questionnaire. The respondents approved all statements which stressed the potential of the system to serve as an additional learning resource for anatomical education. In this case, emphasis was put on active learning, 3-dimensional understanding, and a better comprehension of the course of structures. We are convinced that such an AR MM system can be beneficially installed into anatomical education in order to prepare medical students more effectively for the clinical standards and for more interactive, student-centered learning. Copyright © 2017. Published by Elsevier GmbH.

  8. Blackbody Radiation and the Carbon Particle

    Directory of Open Access Journals (Sweden)

    Robitaille P.-M.

    2008-07-01

    Full Text Available Since the days of Kirchhoff, blackbody radiation has been considered to be a uni- versal process, independent of the nature and shape of the emitter. Nonetheless, in promoting this concept, Kirchhoff did require, at the minimum, thermal equilibrium with an enclosure. Recently, the author stated (P.-M. Robitaille, IEEE Trans. Plasma Sci. , 2003, v. 31(6, 1263–1267; P.-M. Robitaille, Progr. in Phys. , 2006, v. 2, 22–23, that blackbody radiation is not universal and has called for a return to Stewart’s law (P.-M. Robitaille, Progr. in Phys. , 2008, v. 3, 30–35. In this work, a historical analysis of thermal radiation is presented. It is demonstrated that soot, or lampblack, was the standard for blackbody experiments throughout the 1800s. Furthermore, graphite and carbon black continue to play a central role in the construction of blackbody cavities. The advent of universality is reviewed through the writings of Pierre Prevost, Pierre Louis Dulong, Alexis Therese Petit, Jean Baptiste Joseph Fourier, Simeon Denis Pois- son, Frederick Herve de la Provostaye, Paul Quentin Desain, Balfour Stewart, Gustav Robert Kirchhoff, and Max Karl Ernst Ludwig Planck. These writings illustrate that blackbody radiation, as experimentally produced in cavities and as discussed theoreti- cally, has remained dependent on thermal equilibrium with at least the smallest carbon particle. Finally, Planck’s treatment of Kirchhoff’s law is examined in detail and the shortcomings of his derivation are outlined. It is shown once again, that universality does not exist. Only Stewart’s law of thermal emission, not Kirchhoff’s, is fully valid.

  9. Blackbody Radiation and the Carbon Particle

    Directory of Open Access Journals (Sweden)

    Pierre-Marie Robitaille

    2008-07-01

    Full Text Available Since the days of Kirchhoff, blackbody radiation has been considered to be a universal process, independent of the nature and shape of the emitter. Nonetheless, in promoting this concept, Kirchhoff did require, at the minimum, thermal equilibrium with an enclosure. Recently, the author stated (P.-M. Robitaille, IEEE Trans. Plasma Sci., 2003, v.31(6, 1263-1267; P.-M. Robitaille, Progr. in Phys., 2006, v.2, 22-23, that blackbody radiation is not universal and has called for a return to Stewart's law (P.-M. Robitaille, Progr. in Phys., 2008, v.3, 30-35. In this work, a historical analysis of thermal radiation is presented. It is demonstrated that soot, or lampblack, was the standard for blackbody experiments throughout the 1800s. Furthermore, graphite and carbon black continue to play a central role in the construction of blackbody cavities. The advent of universality is reviewed through the writings of Pierre Prevost, Pierre Louis Dulong, Alexis Therese Petit, Jean Baptiste Joseph Fourier, Simeon Denis Poisson, Frederick Herve de la Provostaye, Paul Quentin Desain, Balfour Stewart, Gustav Robert Kirchhoff, and Max Karl Ernst Ludwig Planck. These writings illustrate that blackbody radiation, as experimentally produced in cavities and as discussed theoretically, has remained dependent on thermal equilibrium with at least the smallest carbon particle. Finally, Planck's treatment of Kirchhoff's law is examined in detail and the shortcomings of his derivation are outlined. It is shown once again, that universality does not exist. Only Stewart's law of thermal emission, not Kirchhoff's, is fully valid.

  10. Long-Term Health Impact of Early Nutrition: The Power of Programming.

    Science.gov (United States)

    Koletzko, Berthold; Brands, Brigitte; Grote, Veit; Kirchberg, Franca F; Prell, Christine; Rzehak, Peter; Uhl, Olaf; Weber, Martina

    2017-01-01

    The Power of Programming conference 2016 at Ludwig-Maximilians-Universität Munich brought together about 600 researchers and other stakeholders from around the world who reviewed the recent evidence on the lasting health impact of environment and nutrition during early life, from pre-pregnancy to early childhood. The conference was hosted by the Early Nutrition Project, a multidisciplinary research collaboration funded by the European Commission with collaborating researchers from 35 institutions in 15 countries in Europe, the United States and Australia. The project explores the early origins of obesity, adiposity and associated non-communicable diseases, underlying mechanisms and opportunities for prevention. The project also proactively supports translational application of research findings. In fact, some existing evidence has already been rapidly adopted into policy, regulatory standards and practice. Further, broad dissemination of findings is achieved through the established digital eLearning platform of the Early Nutrition eAcademy, video clip-based learning and graphically supported messaging to consumers. The project demonstrated powerful effects of early metabolic programming on later health. Compared to other common prevention strategies, modifying risk trajectories in early life can achieve a much larger risk reduction and be more cost-effective. While some effective prevention strategies have been promptly implemented in policy and guidelines, legislation and practice, in other areas, the uptake is limited by a paucity of quality human intervention trials and insufficient evaluation of the feasibility of implementation and econometric impact. This needs to be strengthened by future collaborative research work. © 2017 S. Karger AG, Basel.

  11. Knowledge and awareness of medical doctors, medical students and nurses about dentistry in Nigeria.

    Science.gov (United States)

    Oyetola, Elijah Olufemi; Oyewole, Taiwo; Adedigba, Micheal; Aregbesola, Stephen Tunde; Umezudike, Kehinde; Adewale, Adedotun

    2016-01-01

    Various studies have reported poor awareness and knowledge of dentistry in the Nigerian population. There is, however, paucity of information assessing the knowledge and awareness of medical doctors/students and nurses about dentistry. The present study is aimed at determining the knowledge and awareness of medical doctors/students and nurses about dentistry. Self-administered questionnaires were randomly distributed among medical doctors/students, and nurses of Obafemi Awolowo Teaching Hospitals' Complex, Ile-Ife, Nigeria. Information collected using the questionnaire included participants' biodata, questions evaluating dental awareness, knowledge of systemic and oral health connections as well as referral practices. The data analysis was done with STATA version 11 software. A total of 300 questionnaires were randomly distributed among doctors/students and nurses, 206 were returned (response rate of 69%). Of the returned questionnaires, 129(63%) were males and 77(37%) were females. There were 42 medical doctors, 49 nurses and 115 medical students. The mean age of the participants was 26.7 years (SD 5.2). Majority (99.5%) was aware of dental profession, but 92% had never referred patients for dental consultation. One third (31%) of medical doctors believed that Ludwig angina was a cardiac disease. A large proportion of the respondents (61%) see no need for routine dental visit while 27% would want to visit the dentist only when they had a dental complaint. Although a large percentage of the participants claimed to be aware of dentistry, our findings revealed low level of knowledge and attitude to Dentistry. Efforts should be made towards closing this knowledge gap to achieve efficient oral health.

  12. Spin-Orbit Misalignments of Three Jovian Planets via Doppler Tomography

    Science.gov (United States)

    Johnson, Marshall C.; Cochran, William D.; Addison, Brett C.; Tinney, Chris G.; Wright, Duncan J.

    2017-10-01

    We present measurements of the spin-orbit misalignments of the hot Jupiters HAT-P-41 b and WASP-79 b, and the aligned warm Jupiter Kepler-448 b. We obtain these measurements with Doppler tomography, where we spectroscopically resolve the line profile perturbation during the transit due to the Rossiter-McLaughlin effect. We analyze time series spectra obtained during portions of five transits of HAT-P-41 b, and find a value of the spin-orbit misalignment of λ =-{22.1}-6.0{+0.8^\\circ }. We reanalyze the radial velocity Rossiter-McLaughlin data on WASP-79 b obtained by Addison et al. using Doppler tomographic methodology. We measure λ =-{99.1}-3.9{+4.1^\\circ }, consistent with but more precise than the value found by Addison et al. For Kepler-448 b we perform a joint fit to the Kepler light curve, Doppler tomographic data, and a radial velocity data set from Lillo-Box et al. We find an approximately aligned orbit (λ =-{7.1}-2.8{+4.2^\\circ }), in agreement with the value found by Bourrier et al. Through analysis of the Kepler light curve we measure a stellar rotation period of {P}{rot}=1.27+/- 0.11 days, and use this to argue that the full three-dimensional spin-orbit misalignment is small, \\psi ˜ 0^\\circ . Based in part on observations obtained with the Hobby-Eberly Telescope, which is a joint project of the University of Texas at Austin, the Pennsylvania State University, Stanford University, Ludwig-Maximilians-Universität München, and Georg-August-Universität Göttingen.

  13. Heart rate variability - a historical perspective.

    Science.gov (United States)

    Billman, George E

    2011-01-01

    Heart rate variability (HRV), the beat-to-beat variation in either heart rate or the duration of the R-R interval - the heart period, has become a popular clinical and investigational tool. The temporal fluctuations in heart rate exhibit a marked synchrony with respiration (increasing during inspiration and decreasing during expiration - the so called respiratory sinus arrhythmia, RSA) and are widely believed to reflect changes in cardiac autonomic regulation. Although the exact contributions of the parasympathetic and the sympathetic divisions of the autonomic nervous system to this variability are controversial and remain the subject of active investigation and debate, a number of time and frequency domain techniques have been developed to provide insight into cardiac autonomic regulation in both health and disease. It is the purpose of this essay to provide an historical overview of the evolution in the concept of HRV. Briefly, pulse rate was first measured by ancient Greek physicians and scientists. However, it was not until the invention of the "Physician's Pulse Watch" (a watch with a second hand that could be stopped) in 1707 that changes in pulse rate could be accurately assessed. The Rev. Stephen Hales (1733) was the first to note that pulse varied with respiration and in 1847 Carl Ludwig was the first to record RSA. With the measurement of the ECG (1895) and advent of digital signal processing techniques in the 1960s, investigation of HRV and its relationship to health and disease has exploded. This essay will conclude with a brief description of time domain, frequency domain, and non-linear dynamic analysis techniques (and their limitations) that are commonly used to measure HRV.

  14. Heart Rate Variability - A Historical Perspective

    Directory of Open Access Journals (Sweden)

    George E Billman

    2011-11-01

    Full Text Available Heart rate variability (HRV, the beat-to-beat variation in either heart rate or the duration of the R-R interval – the heart period, has become a popular clinical and investigational tool. The temporal fluctuations in heart rate exhibit a marked synchrony with respiration (increasing during inspiration and decreasing during expiration – the so called respiratory sinus arrhythmia, RSA and are widely believed to reflect changes in cardiac autonomic regulation. Although the exact contributions of the parasympathetic and the sympathetic divisions of the autonomic nervous system to this variability are controversial and remain the subject of active investigation and debate, a number of time and frequency domain techniques have been developed to provide insight into cardiac autonomic regulation in both health and disease. It is the purpose of this essay to provide an historical overview of the evolution in the concept of heart rate variability. Briefly, pulse rate was first measured by ancient Greek physicians and scientists. However, it was not until the invention of the Physician’s Pulse Watch (a watch with a second hand that could be stopped in 1707 that changes in pulse rate could be accurately assessed. The Rev. Stephen Hales (1733 was the first to note that pulse varied with respiration and in 1847 Carl Ludwig was the first to record RSA. With the measurement of the ECG (1895 and advent of digital signal processing techniques in the 1960’s, investigation of HRV and its relationship to health and disease has exploded. This essay will conclude with a brief description of time domain, frequency domain, and non-linear dynamic analysis techniques (and their limitations that are commonly used to measure heart rate variability.

  15. Meniscectomy: indications, procedure, outcomes, and rehabilitation

    Directory of Open Access Journals (Sweden)

    Anetzberger H

    2013-12-01

    Full Text Available Hermann Anetzberger,1 Christof Birkenmaier,2 Stephan Lorenz3 1Orthopädische Gemeinschaftspraxis am OEZ, Munich, Germany; 2Department of Orthopedics, Ludwig-Maximilian-University Munich, Munich, Germany; 3Department of Orthopedic Sports Medicine, Technical University of Munich, Klinikum rechts der Isar, Munich, Germany Abstract: Meniscal injuries are among the most frequent reasons for knee problems. The goal of this manuscript is to review the biomechanical relevance of the human knee's menisci in relation to surgical indications, surgical techniques, rehabilitation, and outcomes. In order to identify the relevant literature, we performed a PubMed search for the years ranging from 1980–2013 using the following search terms: meniscus; biomechanical function; meniscectomy; meniscal repair; and clinical outcome. The meniscus helps to distribute the forces between the tibial and femoral articular cartilage layers in a load-sharing capacity. Meniscus damage or meniscectomy intuitively leads to an overloading of the cartilage and, hence, to the development of osteoarthrosis. Precise knowledge of meniscal shape and function, of the type of injury, of surgical techniques, as well as of postsurgical rehabilitative care are of decisive importance for an individually-adjusted treatment strategy. Other underlying coexisting knee pathologies also need to be considered. The diagnosis of a meniscal injury is based upon clinical history, physical examination, and imaging studies. The treatment of a meniscal lesion includes conservative, as well as operative, procedures. The goals of surgery are to reduce pain and disability, as well as to preserve meniscal function without causing additional cartilage damage. The resection of meniscal tissue should be restricted to as much as is necessary, and as little as is reasonably possible. Postoperative rehabilitation serves the purpose of improving functional deficits and pain, as well as of restoring a good range of

  16. Neuer Atheismus: New Atheism in Germany

    Directory of Open Access Journals (Sweden)

    Thomas Zenk

    2012-06-01

    Full Text Available Matthias Knutzen (born 1646 – died after 1674 was the first author we know of who self-identified as an atheist (Schröder 2010: 8. Before this, the term had solely been used pejoratively to label others. While Knutzen is almost completely forgotten now, authors such as Ludwig Feuerbach, Karl Marx, Friedrich Nietzsche, or Sigmund Freud are better remembered and might even be considered classic writers in the history of the atheist criticism of religion. Whatever may be said about the influence of any one of these authors, there is no doubt that Germany looks back on a notable history in this field. About a decade ago, Germany’s capital Berlin was even dubbed ‘the world capital of atheism’ by the American sociologist Peter L. Berger (2001: 195.Given this situation, I am bewildered by the expression ‘New Atheism’. Yet, undoubtedly, the term has become a catchphrase that is commonly used in the public discourse of several countries. The most prominent authors to be labelled ‘New Atheists’ are Richard Dawkins (The God Delusion, 2006, Daniel Dennett (Breaking the Spell: Religion as a Natural Phenomenon, 2006, Sam Harris (The End of Faith: Religion, Terror, and the Future of Reason, 2004, and Letter to a Christian Nation, 2006, and Christopher Hitchens (God Is Not Great: How Religion Poisons Every­thing, 2007. These authors and their books – all of them international bestsellers – have been intensely discussed around the world, including in Germany. In this paper, I intend to illuminate some of the characteristics and remarkable traits of the German discourse on the ‘New Atheism’. Here we can distinguish between two phases. The German media initially characterised ‘New Atheism’ as a rather peculiarly American phenomenon. However, it soon came to be understood to be a part of German culture as well.

  17. Musical beauty and information compression: Complex to the ear but simple to the mind?

    Science.gov (United States)

    Hudson, Nicholas J

    2011-01-20

    The biological origin of music, its universal appeal across human cultures and the cause of its beauty remain mysteries. For example, why is Ludwig Van Beethoven considered a musical genius but Kylie Minogue is not? Possible answers to these questions will be framed in the context of Information Theory. The entire life-long sensory data stream of a human is enormous. The adaptive solution to this problem of scale is information compression, thought to have evolved to better handle, interpret and store sensory data. In modern humans highly sophisticated information compression is clearly manifest in philosophical, mathematical and scientific insights. For example, the Laws of Physics explain apparently complex observations with simple rules. Deep cognitive insights are reported as intrinsically satisfying, implying that at some point in evolution, the practice of successful information compression became linked to the physiological reward system. I hypothesise that the establishment of this "compression and pleasure" connection paved the way for musical appreciation, which subsequently became free (perhaps even inevitable) to emerge once audio compression had become intrinsically pleasurable in its own right. For a range of compositions, empirically determine the relationship between the listener's pleasure and "lossless" audio compression. I hypothesise that enduring musical masterpieces will possess an interesting objective property: despite apparent complexity, they will also exhibit high compressibility. Artistic masterpieces and deep Scientific insights share the common process of data compression. Musical appreciation is a parasite on a much deeper information processing capacity. The coalescence of mathematical and musical talent in exceptional individuals has a parsimonious explanation. Musical geniuses are skilled in composing music that appears highly complex to the ear yet transpires to be highly simple to the mind. The listener's pleasure is influenced

  18. Alternation Frequency Thresholds for Stereopsis as a Technique for Exploring Stereoscopic Difficulties

    Directory of Open Access Journals (Sweden)

    Svetlana Rychkova

    2011-01-01

    Full Text Available When stereoscopic images are presented alternately to the two eyes, stereopsis occurs at F ⩾ 1 Hz full-cycle frequencies for very simple stimuli, and F ⩾ 3 Hz full-cycle frequencies for random-dot stereograms (eg Ludwig I, Pieper W, Lachnit H, 2007 “Temporal integration of monocular images separated in time: stereopsis, stereoacuity, and binocular luster” Perception & Psychophysics 69 92–102. Using twenty different stereograms presented through liquid crystal shutters, we studied the transition to stereopsis with fifteen subjects. The onset of stereopsis was observed during a stepwise increase of the alternation frequency, and its disappearance was observed during a stepwise decrease in frequency. The lowest F values (around 2.5 Hz were observed with stimuli involving two to four simple disjoint elements (circles, arcs, rectangles. Higher F values were needed for stimuli containing slanted elements or curved surfaces (about 1 Hz increment, overlapping elements at two different depths (about 2.5 Hz increment, or camouflaged overlapping surfaces (> 7 Hz increment. A textured cylindrical surface with a horizontal axis appeared easier to interpret (5.7 Hz than a pair of slanted segments separated in depth but forming a cross in projection (8 Hz. Training effects were minimal, and F usually increased as disparities were reduced. The hierarchy of difficulties revealed in the study may shed light on various problems that the brain needs to solve during stereoscopic interpretation. During the construction of the three-dimensional percept, the loss of information due to natural decay of the stimuli traces must be compensated by refreshes of visual input. In the discussion an attempt is made to link our results with recent advances in the comprehension of visual scene memory.

  19. ARFI cut-off values and significance of standard deviation for liver fibrosis staging in patients with chronic liver disease.

    Science.gov (United States)

    Goertz, Ruediger S; Sturm, Joerg; Pfeifer, Lukas; Wildner, Dane; Wachter, David L; Neurath, Markus F; Strobel, Deike

    2013-01-01

    Acoustic radiation force impulse (ARFI) elastometry quantifies hepatic stiffness, and thus degree of fibrosis, non-invasively. Our aim was to analyse the diagnostic accuracy of ARFI cut-off values, and the significance of a defined limit of standard deviation (SD) as a potential quality parameter for liver fibrosis staging in patients with chronic liver diseases (CLD). 153 patients with CLD (various aetiologies) undergoing liver biopsy, and an additional 25 patients with known liver cirrhosis, were investigated. ARFI measurements were performed in the right hepatic lobe, and correlated with the histopathological Ludwig fibrosis score (inclusion criteria: at least 6 portal tracts). The diagnostic accuracy of cut-off values was analysed with respect to an SD limit of 30% of the mean ARFI value. The mean ARFI elastometry showed 1.95 ± 0.87 m/s (range 0.79-4.40) in 178 patients (80 female, 98 male, mean age: 52 years). The cut-offs were 1.25 m/s for F ≥ 2, 1.72 m/s for F ≥ 3 and 1.75 m/s for F = 4, and the corresponding AUROC 80.7%, 86.2% and 88.7%, respectively. Exclusion of 31 patients (17.4%) with an SD higher than 30% of the mean ARFI improved the diagnostic accuracy: The AUROC for F ≥ 2, F ≥ 3 and F = 4 were 86.1%, 91.2% and 91.5%, respectively. The diagnostic accuracy of ARFI can be improved by applying a maximum SD of 30% of the mean ARFI as a quality parameter--which however leads to an exclusion of a relevant number of patients. ARFI results with a high SD should be interpreted with caution.

  20. The XIIIth International Physiological Congress in Boston in 1929: American physiology comes of age.

    Science.gov (United States)

    Rall, Jack A

    2016-03-01

    In the 19th century, the concept of experimental physiology originated in France with Claude Bernard, evolved in Germany stimulated by the teaching of Carl Ludwig, and later spread to Britain and then to the United States. The goal was to develop a physicochemical understanding of physiological phenomena. The first International Physiological Congress occurred in 1889 in Switzerland with an emphasis on experimental demonstrations. The XIIIth Congress, the first to be held outside of Europe, took place in Boston, MA, in 1929. It was a watershed meeting and indicated that American physiology had come of age. Meticulously organized, it was the largest congress to date, with over 1,200 participants from more than 40 countries. Getting to the congress was a cultural adventure, especially for the 400 scientists and their families from over 20 European countries, who sailed for 10 days on the S.S. Minnekahda. Many of the great physiologists of the world were in attendance, including 22 scientists who were either or would become Nobel Laureates. There were hundreds of platform presentations and many experimental demonstrations. The meeting was not without controversy as a conflict, still not completely settled, arose over the discovery of ATP. After the meeting, hundreds of participants made a memorable trip to the Marine Biological Laboratory at Woods Hole, MA, which culminated in a "good old fashioned Cape Cod Clambake." Although not as spectacular as the 1929 congress, the physiological congresses have continued with goals similar to those established more than a century ago. Copyright © 2016 The American Physiological Society.

  1. Attenuation correction in emission tomography using the emission data—A review

    Energy Technology Data Exchange (ETDEWEB)

    Berker, Yannick, E-mail: berker@mail.med.upenn.edu; Li, Yusheng [Department of Radiology, University of Pennsylvania, 3620 Hamilton Walk, Philadelphia, Pennsylvania 19104 (United States)

    2016-02-15

    The problem of attenuation correction (AC) for quantitative positron emission tomography (PET) had been considered solved to a large extent after the commercial availability of devices combining PET with computed tomography (CT) in 2001; single photon emission computed tomography (SPECT) has seen a similar development. However, stimulated in particular by technical advances toward clinical systems combining PET and magnetic resonance imaging (MRI), research interest in alternative approaches for PET AC has grown substantially in the last years. In this comprehensive literature review, the authors first present theoretical results with relevance to simultaneous reconstruction of attenuation and activity. The authors then look back at the early history of this research area especially in PET; since this history is closely interwoven with that of similar approaches in SPECT, these will also be covered. We then review algorithmic advances in PET, including analytic and iterative algorithms. The analytic approaches are either based on the Helgason–Ludwig data consistency conditions of the Radon transform, or generalizations of John’s partial differential equation; with respect to iterative methods, we discuss maximum likelihood reconstruction of attenuation and activity (MLAA), the maximum likelihood attenuation correction factors (MLACF) algorithm, and their offspring. The description of methods is followed by a structured account of applications for simultaneous reconstruction techniques: this discussion covers organ-specific applications, applications specific to PET/MRI, applications using supplemental transmission information, and motion-aware applications. After briefly summarizing SPECT applications, we consider recent developments using emission data other than unscattered photons. In summary, developments using time-of-flight (TOF) PET emission data for AC have shown promising advances and open a wide range of applications. These techniques may both remedy

  2. The impact of health technology assessment reports on decision making in Austria.

    Science.gov (United States)

    Zechmeister, Ingrid; Schumacher, Ines

    2012-01-01

    Health technology assessment (HTA) was established in Austria in the 1990s and, since then, it has gained considerable importance. In this study, we aim to analyze whether the HTA reports that have been produced at the Institute for Technology Assessment (ITA) and at the Ludwig Boltzmann Institute for HTA (LBI-HTA) have had an impact on decision making within the Austrian health care system. We selected all reports that were intended for supporting (i) reimbursement/investment or (ii) disinvestment decisions. Eleven full HTA reports and fifty-eight rapid assessments fulfilled the inclusion criteria. We used interview data and administrative data on volumes, tariffs and expenditure of products/services to analyze whether and how reports were in reality used in decision making and what the consequences for health care expenditure and resource distribution have been. Five full HTA reports and fifty-six rapid technology assessments were used for reimbursement decisions. Four full HTA reports and two rapid assessments were used for disinvestment decisions and resulted in reduced volumes and expenditure. Two full HTA reports showed no impact on decision making. Impact was most evident for hospital technologies. HTA has played some role in reducing volumes of over-supplied hospital technologies, resulting in reduced expenditure for several hospital providers. Additionally, it has been increasingly included in prospective planning and reimbursement decisions of late, indicating re-distribution of resources toward evidence-based technologies. However, further factors may have influenced the decisions, and the impact could be considerably increased by systematically incorporating HTA into the decision-making process in Austria.

  3. [Animal testing ethics and human testing. Thoughts on our conduct with and our relationship to animals].

    Science.gov (United States)

    Locker, Alfred

    2004-01-01

    After many years of experimental work with animals of diverse species, the author felt confronted with the question whether the great expenditure of sacrificed animal life would pay off when compared with the results gained. By self-critically considering his work, he gradually experienced a conversion from an unconcerned experimenter to a man feeling a deep sympathy with his fellow creatures. This motivated him to ponder the true nature of animals. Instead of applying ethics--though justified in its own realm--the author preferred to look at the problem using the General Systems Theory (GST), which can describe "the other side" of any system, the side into which any system may occasionally or necessarily transform. It occurred to him to assume that--provided we see a living organism as a system (as Ludwig von Bertalanffy, the founder of GST, did)--the "other side" of the animal would correspond to an innocent "genius" who suffers for man (thereby assuming a Christ-like position), whereas in its transitory life the true essence of the animal is hidden. Thus, by fancifully viewing the role of animals destined to suffer, a connection between GST and theology or religion arises. The consequence for us would be to pay honour to the test animal, irrespective of whether or not painful experiments could be avoided. The differentiation between a sacrifice (spiritually surrendering for a greater good) and a victim (involuntarily subjected to suffering) reveals that the experimental animal primarily belongs to the latter. But it can be elevated to the former when the full meaning of its suffering becomes obvious. The same holds true for "human testing", if, in contrast to the formidable atrocities, e.g. of concentration camps, the momentum of voluntariness is guaranteed, as pioneers of medical research frequently demonstrated by carrying out experiments on themselves.

  4. From Magnetotactic Bacteria to Sediment Magnetizations: new insights

    Science.gov (United States)

    Egli, R.; Mao, X.; Zhao, X.

    2015-12-01

    Magnetotactic bacteria (MTB) represent one of the most intriguing examples of iron biomineralization and magnetic navigation in nature. MTB synthesize magnetic nanocrystals, called magnetosomes, which act as an incorporated compass for navigation purposes (magnetotaxis). MTB are ubiquitous organisms living in chemically stratified freshwater and marine environments, where they contribute significantly to the Fe cycle. Magnetosomes accumulate as fossil MTB remains in sediment (magnetofossils). The recent development of magnetic measurement protocols enabling to detect small magnetosome concentrations among complex iron mineral mixtures led to the discovery that magnetofossil preservation over geological times is not uncommon. Therefore, magnetofossils can play an important role in sedimentary records of the Earth's magnetic field, as well as conveying selective information about past environmental conditions (e.g. redox conditions and nutrient concentration). Paleomagnetic and environmental applications require us to understand the processes that control MTB occurrence, magnetofossil formation and preservation, and the final alignment with the Earth's magnetic field. Our current knowledge relies mostly on experiments performed with cultured MTB in aqueous solutions, under physical and chemical conditions that do not necessarily reproduce those encountered in sediment. These experiments have been pivotal for understanding magnetosome growth and the fundaments of magnetotaxis. On the other hand, recent investigations of living MTB populations in sediment with specially developed observation techniques led to unexpected findings, with important implications for magnetotaxis models, MTB ecology, and, indirectly, for modeling the acquisition of natural magnetizations in bioturbated sediments. Ludwig, P. et al. (2013), Global Planet. Change 110, 321-339. Mao, X. et al. (2014), Geochem. Geophys. Geosys. 15, doi:10.1002/2013GC005034. Mao, X. et al. (2014). PLoS ONE 9, doi

  5. Detection of a fluorescent-labeled avidin-nucleic acid nanoassembly by confocal laser endomicroscopy in the microvasculature of chronically inflamed intestinal mucosa

    Directory of Open Access Journals (Sweden)

    Buda A

    2015-01-01

    Full Text Available Andrea Buda,1,* Sonia Facchin,1,* Elisa Dassie,2 Elisabetta Casarin,3 Mark A Jepson,4 Helmut Neumann,5 Giorgia Hatem,1 Stefano Realdon,6 Renata D’Incà,1 Giacomo Carlo Sturniolo,1 Margherita Morpurgo3 1Department of Surgical, Oncological, and Gastroenterological Sciences, University of Padova, 2Department of Molecular Medicine, University of Padova, Padova, Italy; 3Department of Pharmaceutical and Pharmacological Sciences, University of Padova, Padova, Italy; 4School of Biochemistry and Wolfson Bioimaging Facility, University of Bristol, Bristol, UK; 5Ludwig Demlig Endoscopic Center of Excellence, ESGE Endoscopy Training Center, University of Erlangen-Nuremberg, Erlangen, Germany; 6Veneto Institute of Oncology IOV-IRCCS, Padova, Italy *These authors contributed equally to this work Abstract: Inflammatory bowel diseases are chronic gastrointestinal pathologies causing great discomfort in both children and adults. The pathogenesis of inflammatory bowel diseases is not yet fully understood and their diagnosis and treatment are often challenging. Nanoparticle-based strategies have been tested in local drug delivery to the inflamed colon. Here, we have investigated the use of the novel avidin-nucleic acid nanoassembly (ANANAS platform as a potential diagnostic carrier in an experimental model of inflammatory bowel diseases. Fluorescent-labeled ANANAS nanoparticles were administered to mice with chemically induced chronic inflammation of the large intestine. Localization of mucosal nanoparticles was assessed in vivo by dual-band confocal laser endomicroscopy. This technique enables characterization of the mucosal microvasculature and crypt architecture at subcellular resolution. Intravascular nanoparticle distribution was observed in the inflamed mucosa but not in healthy controls, demonstrating the utility of the combination of ANANAS and confocal laser endomicroscopy for highlighting intestinal inflammatory conditions. The specific localization of

  6. Prospective validation of FibroTest in comparison with liver stiffness for predicting liver fibrosis in Asian subjects with chronic hepatitis B.

    Directory of Open Access Journals (Sweden)

    Beom Kyung Kim

    Full Text Available Diagnostic values of FibroTest (FT for hepatic fibrosis have rarely been assessed in Asian chronic hepatitis B (CHB patients. We aimed to validate its diagnostic performances in comparison with liver stiffness (LS.From 2008 to 2010, 194 CHB patients who underwent liver biopsies along with FT and transient elastography were prospectively enrolled. Fibrosis stage was assessed according to the Batts and Ludwig system.To predict significant fibrosis (F≥2, advanced fibrosis (F≥3, and cirrhosis (F = 4, areas under receiver operating characteristic curves (AUROCs of FT were 0.903, 0.907, and 0.866, comparable to those of LS (0.873, 0.897, and 0.910, respectively. Optimized cutoffs of FT to maximize sum of sensitivity and specificity were 0.32, 0.52, and 0.68 for F≥2, F≥3, and F = 4, while those of LS were 8.8, 10.2, and 14.1 kPa, respectively. According to FT and LS cutoffs, 123 (63.4% and 124 (63.9% patients were correctly classified consistent with histological fibrosis (F1, F2, F3, and F4, respectively. Overall concordance between each fibrosis stage estimated by FT and LS was observed in 111 patients, where 88 were correctly classified with histological results. A combination formula adding LS to FT (LS+FT showed similar AUROC levels (0.885, 0.905, and 0.915, while another multiplying LS by FT (LS×FT showed the best AUROCs (0.941, 0.931, and 0.929 for F≥2, F≥3, and F4, respectively.FT provides good fibrosis prediction, with comparable outcomes to LS in Asian CHB patients. FT substantially reduces need for liver biopsy, especially when used in combination with LS.

  7. Philosophical and Ethical Foundations of Systems Thinking

    Directory of Open Access Journals (Sweden)

    Debora Hammond

    2008-07-01

    Full Text Available Drawing on more than a decade of research on the social implications of systems thinking, as well as practical experience in integrative, community-based approaches to education, this paper is an inquiry into philosophical and ethical considerations growing out of recent developments in systems thinking. In his foundational work on general system theory, Ludwig von Bertalanffy distinguishes between three general developments in the systems field: systems technology, systems science, and systems philosophy. These three dimensions of systems thinking each nurture distinct and often widely divergent theoretical and practical orientations. In his abstract for this session, Gary Metcalf asks whether the systems approach really has anything to offer. Science is a form of social feedback; it has created an enormous body of knowledge about the world and shaped humanity’s understanding of the nature of our collective reality. Knowledge then informs action. Assumptions built into scientific frameworks condition certain kinds of actions, as Bertalanffy has noted. Systems thinking as science nurtures a way of thinking that engenders a different kind of practice; systems as philosophy cultivates an ethic of integration and collaboration that has the potential to transform the nature of social organization. Although humanity still has a lot to learn about living more harmoniously and sustainably, systems thinking has made significant contributions in this direction in many fields, both theoretical and practical. The challenge is to integrate what we have learned, to communicate these insights to a larger audience, and to nurture institutional practices that honor the ethical principles inherent in the systems view.

  8. Energetic use of renewable fuels. Logistics of energy carrier supply, technologies of usage, boundary conditions for economically efficient use of biomass. Proceedings; Energetische Nutzung nachwachsender Rohstoffe - Logistik der Energietraegerbereitstellung, Technologien der Energietraegernutzung, Rahmenbedinungen fuer den wirtschaftlichen Einsatz von Biomasse. Vortraege

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2008-07-01

    Within the 14th international conference 'Energetical use of renewable fuels' at Freiberg (Federal Republic of Germany) at 11th and 12th September, 2008, the following lectures were held: (a) State of the legislation procedure for the revision of the Renewable Energy Resources Act and Renewable Energy Resources Heat Act (Bernhard Dreher); (b) Power generation from biomass - A task of investigation? (Martin Kaltschmitt); (c) A physical-chemical online analysis of fine dust emissions from wood furnaces (Michael Sattler, Christian Gaegauf, Nicolas Meyer, Maaren Heringa); (d) Actual state of standardization of biogenic solid fuels (Andreas Neff, Frank Baur); (e) Combined heat and power coupling with thermal gasification of biomass - State of the art and actual developments (Juergen Karl); (f) Wood power generation in the practice - Possibilities and potentials (Michael Hoeffling); (g) Biological natural gas - An analysis and evaluation (Alexander Vogel, Stephan Ramesohl); (h) Digestion of biomass ensures a high yield of biogas (Thilo Lehmann, Christina Dornack); (i) Market for wood pellets in the Federal Republic of Germany - State of the art, development, perspectives (Martin Bentele); (j) Report on the expert opinion ''Utilization of biomass for power generation'' of the Scientific Advisory Council agrarian policy at BMELV (Thomas De Witte); (k) About the ecology of short rotation plants (Heino Wolf); (l) Generation of electricity and heat on the basis of straw - The first straw-fired heating plant in Germany (Rainer Knieper); (m) Standardization of liquid fuels in European context (Thomas Brehmer, Franz Heger); (n) Bio fuels of the second generation: Production, quantities of biomass and strategies of supply (Lutz Freytag); (o) Biomass-fired heating plant Simmering (Ludwig Gockner); (p) Industrial network Renewably Energy in the Free State of Saxony (Klaus Beumler); (q) Exemplary regional conversion of an intelligent, decentralised

  9. Austrian Economics and the Transaction Cost Approach to the Firm

    Directory of Open Access Journals (Sweden)

    Nicolai J. Foss

    2009-10-01

    Full Text Available As the transaction cost theory of the firm was taking shape in the 1970s, another important movement in economics was emerging: a revival of the ‘Austrian’ tradition in economic theory associated with such economists as Ludwig von Mises and F. A. Hayek (1973; Dolan, 1976; Spadaro, 1978. As Oliver Williamson has pointed out, Austrian economics is among the diverse sources for transaction cost economics. In particular, Williamson frequently cites Hayek (e.g., Williamson, 1985, p. 8; 1991, p. 162, particularly Hayek’s emphasis on adaptation as a key problem of economic organisation (Hayek, 1945. Following Williamson’s lead, a reference to Hayek’s ‘The Use of Knowledge in Society’ (Hayek, 1945 has become almost mandatory in discussions of economic organisation (e.g., Ricketts, 1987, p. 59; Milgrom and Roberts, 1992, p. 56; Douma and Schreuder 1991, p. 9. However, there are many other potential links between Austrian and transaction cost economics that have not been explored closely and exploited.This article argues that characteristically Austrian ideas about property, entrepreneurship, economic calculation, tacit knowledge, and the temporal structure of capital have important implications for theories of economic organisation, transaction cost economics in particular. Austrian economists have not, however, devoted substantial attention to the theory of the firm, preferring to focus on business-cycle theory, welfare economics, political economy, comparative economic systems, and other areas. Until recently the theory of the firm was an almost completely neglected area in Austrian economics, but over the last decade, a small Austrian literature on the firm has emerged. While these works cover a wide variety of theoretical and applied topics, their authors share the view that Austrian insights have something to offer students of firm organisation.

  10. Correlation between peripapillary retinal nerve fiber layer thickness and fundus autofluorescence in primary open-angle glaucoma

    Directory of Open Access Journals (Sweden)

    Reznicek L

    2013-09-01

    Full Text Available Lukas Reznicek,* Florian Seidensticker,* Thomas Mann, Irene Hübert, Alexandra Buerger, Christos Haritoglou, Aljoscha S Neubauer, Anselm Kampik, Christoph Hirneiss, Marcus Kernt Department of Ophthalmology, Ludwig-Maximilians-University, Munich, Germany *These authors contributed equally to this work Purpose: To investigate the relationship between retinal nerve fiber layer (RNFL thickness and retinal pigment epithelium alterations in patients with advanced glaucomatous visual field defects. Methods: A consecutive, prospective series of 82 study eyes with primary open-angle glaucoma and advanced glaucomatous visual field defects were included in this study. All study participants underwent a full ophthalmic examination followed by visual field testing with standard automated perimetry as well as spectral-domain optical coherence tomography (SD-OCT for peripapillary RNFL thickness and Optos wide-field fundus autofluorescence (FAF images. A pattern grid with corresponding locations between functional visual field sectors and structural peripapillary RNFL thickness was aligned to the FAF images at corresponding location. Mean FAF intensity (range: 0 = black and 255 = white of each evaluated sector (superotemporal, temporal, inferotemporal, inferonasal, nasal, superonasal was correlated with the corresponding peripapillary RNFL thickness obtained with SD-OCT. Results: Correlation analyses between sectoral RNFL thickness and standardized FAF intensity in the corresponding topographic retina segments revealed partly significant correlations with correlation coefficients ranging between 0.004 and 0.376 and were statistically significant in the temporal inferior central field (r = 0.324, P = 0.036 and the nasal field (r = 0.376, P = 0.014. Conclusion: Retinal pigment epithelium abnormalities correlate with corresponding peripapillary RNFL damage, especially in the temporal inferior sector of patients with advanced glaucomatous visual field defects. A

  11. Prolonged closed cardiac massage using LUCAS device in out-of-hospital cardiac arrest with prolonged transport time

    Directory of Open Access Journals (Sweden)

    Edouard Matevossian

    2009-04-01

    Full Text Available Edouard Matevossian1, Dietrich Doll4, Jakob Säckl1, Inga Sinicina5, Jürgen Schneider2, Gerhard Simon3, Norbert Hüser11Department of Surgery, 2Department of Anesthesiology and Intensive-Care Medicine; 3Department of Radiology, Technische Universität of Munich, Germany; 4Department of Visceral, Vascular and Thoracic Surgery, Philips University of Marburg, Marburg, Germany; 5Institute of Clinical Forensic Medicine, Ludwig-Maximilian University of Munich, Munich, GermanyAbstract: Saving more human lives through more effective reanimation measures is the goal of the new international guidelines on cardiopulmonary resuscitation as the decisive aspect for survival after cardiovascular arrest is that basic resuscitation should start immediately. According to the updated guidelines, the greatest efficacy in cardiac massage is only achieved when the right compression point, an adequate compression depth, vertical pressure, the correct frequency, and equally long phases of compression and decompression are achieved. The very highest priority is placed on restoring continuous circulation. Against this background, standardized continuous chest compression with active decompression has contributed to a favorable outcome in this case. The hydraulically operated and variably adjustable automatic Lund University Cardiac Arrest System (LUCAS device (Jolife, Lund, Sweden undoubtedly meets these requirements. This case report describes a 44-year-old patient who – approximately 15 min after the onset of clinical death due to apparent ventricular fibrillation – received cardiopulmonary resuscitation, initially by laypersons and then by the emergency medical team (manual chest compressions followed by situation-adjusted LUCAS compressions. Sinus rhythm was restored after more than 90 min of continuous resuscitation, with seven defibrillations. Interventional diagnostic workup did not reveal a causal morphological correlate for the condition on coronary

  12. Liposomal nanoparticles encapsulating iloprost exhibit enhanced vasodilation in pulmonary arteries

    Directory of Open Access Journals (Sweden)

    Jain PP

    2014-07-01

    Full Text Available Pritesh P Jain,1 Regina Leber,1,2 Chandran Nagaraj,1 Gerd Leitinger,3 Bernhard Lehofer,4 Horst Olschewski,1,5 Andrea Olschewski,1,6 Ruth Prassl,1,4 Leigh M Marsh11Ludwig Boltzmann Institute for Lung Vascular Research, 2Biophysics Division, Institute of Molecular Biosciences, University of Graz, 3Research Unit Electron Microscopic Techniques, Institute of Cell Biology, Histology, and Embryology, 4Institute of Biophysics, 5Division of Pulmonology, Department of Internal Medicine, 6Department of Anesthesiology and Intensive Care Medicine, Medical University of Graz, Graz, AustriaAbstract: Prostacyclin analogues are standard therapeutic options for vasoconstrictive diseases, including pulmonary hypertension and Raynaud’s phenomenon. Although effective, these treatment strategies are expensive and have several side effects. To improve drug efficiency, we tested liposomal nanoparticles as carrier systems. In this study, we synthesized liposomal nanoparticles tailored for the prostacyclin analogue iloprost and evaluated their pharmacologic efficacy on mouse intrapulmonary arteries, using a wire myograph. The use of cationic lipids, stearylamine, or 1,2-di-(9Z-octadecenoyl-3-trimethylammonium-propane (DOTAP in liposomes promoted iloprost encapsulation to at least 50%. The addition of cholesterol modestly reduced iloprost encapsulation. The liposomal nanoparticle formulations were tested for toxicity and pharmacologic efficacy in vivo and ex vivo, respectively. The liposomes did not affect the viability of human pulmonary artery smooth muscle cells. Compared with an equivalent concentration of free iloprost, four out of the six polymer-coated liposomal formulations exhibited significantly enhanced vasodilation of mouse pulmonary arteries. Iloprost that was encapsulated in liposomes containing the polymer polyethylene glycol exhibited concentration-dependent relaxation of arteries. Strikingly, half the concentration of iloprost in liposomes elicited

  13. Characteristics of dune-paleosol-sequences in Fuerteventura. - What should be questioned?

    Science.gov (United States)

    Faust, Dominik; Willkommen, Tobias; Yanes, Yurena; Richter, David; Zöller, Ludwig

    2013-04-01

    Characteristics of dune-paleosol-sequences in Fuerteventura. - What should be questioned? Dominik Faust, TU Dresden, Germany Tobias Willkommen, TU Dresden, Germany Yurena Yanes, CSIC Granada/Cincinatti, Spain/USA David Richter, TU Dresden, Germany Ludwig Zöller, Uni Bayreuth, Germany The northern part of Fuerteventura is characterized by large dune fields. We investigated dune-paleosol-sequences in four pits to establish a robust stratigraphy and to propose a standard section. An interaction of processes like dune formation, soil formation and redeposition of soils and sand are most important to understand the principles of landscape development in the study area. To our mind a process cycle seem to be important: First climbing-dunes are formed by sand of shelf origin. Then soil formation could have taken place. Soil and/or sand were then eroded and deposited at toe slope position. This material in turn is the source of new sand supply and dune formation. The described cycle may be repeated several times and this ping-pong-process holds on. The results are sections composed of dune layers, paleosols and colluvial material interbedded. Fundamental questions still remain unanswered: Is climate change responsable for changes in process combination (e.g. from dune formation to soil formation)? Or are these features due to divergence phenomenon, where different effects/results (dune and soils) may be linked to similar causes (here: climate)? Assuming that different features (soils and dunes) were formed under one climate, increasing soil forming intensity could be mainly a function of decreasing sand supply. This in turn could be caused by reduced sand production (s. ZECH et al. accepted). However geochemical data and mollusc assemblages point to changing environments in space and even climate modifications in time.

  14. Background to EOHSI study

    International Nuclear Information System (INIS)

    Granville, G.

    2004-01-01

    This paper discusses ongoing public concerns regarding the health impacts of sour gas in Pincher Creek. A description of a 90 day toxicity study on hydrogen sulfide (H 2 S) at the Chemical Industry Institute of Toxicology (CIIT) in 3 strains of rodents was presented. A decade by decade review of events concerning gas emissions was provided, including a description of the 1980s lodgepole blowout and an introduction of a sulphide network in Alberta. The creation of a joint proposal for a comprehensive health review from Alberta researchers and the Canadian Association of Petroleum Producers (CAPP) was also outlined. The 1990s heralded an increased level of public participation in sour gas developments and health and odour issues. Details of the Ludwig saga were presented as well as further research studies and the Energy and Utilities Board (EUB) protocols, processes and hearings. In the 1990s, several human volunteer studies were conducted in response to public concerns about neurotoxicity and reproductive developmental effects. After the year 2000, continued public concern has been voiced at EUB hearings and at panel reviews of health effects. It was noted that development and research data has continued to be the cause of public concern and continued calls for additional work and reviews. However, no additional hazards have been identified with ongoing human volunteer studies, environmental levels and enhanced monitors research almost complete. It was concluded that current controversy seemed to downplay or ignore much of the available science. Human and animal data has consistently revealed that there is no evidence of neuro-developmental reproductive effects. It was recommended that power plays should be avoided and that the ongoing human volunteer study should eventually provide results. tabs, figs

  15. Evaluation of a new in-clinic test system to detect feline immunodeficiency virus and feline leukemia virus infection.

    Science.gov (United States)

    Sand, Christina; Englert, Theresa; Egberink, Herman; Lutz, Hans; Hartmann, Katrin

    2010-06-01

    Many in-house tests for the diagnosis of feline immunodeficiency virus (FIV) and feline leukemia virus (FeLV) infection are licensed for use in veterinary practice. A new test with unknown performance has recently appeared on the market. The aims of this study were to define the efficacy of a new in-clinic test system, the Anigen Rapid FIV Ab/FeLV Ag Test, and to compare it with the current leading in-clinic test, the SNAP Kombi Plus FeLV Antigen/FIB Antibody Test. Three-hundred serum samples from randomly selected healthy and diseased cats presented to the Clinic of Small Animal Medicine at Ludwig Maximilian University were tested using both the Anigen Rapid Test and the SNAP Kombi Plus Test. Diagnostic sensitivity, specificity, and positive and negative predictive values were calculated for both tests using Western blot as the gold standard for verification of FIV infection and PCR as the gold standard for FeLV infection. The presence of antibodies against FIV was confirmed by Western blot in 9/300 samples (prevalence 3%). FeLV DNA was detected by PCR in 15/300 samples (prevalence 5%). For FIV infection the Anigen Rapid Test had a sensitivity of 88.9%, specificity of 99.7%, positive predictive value of 88.9%, and negative predictive value of 99.7%. For FeLV infection, the Anigen Rapid Test had a sensitivity of 40.0%, specificity of 100%, positive predictive value of 100%, and negative predictive value of 96.9%. Diagnostic accuracy was similar to that of the SNAP Kombi Plus Test. The new Anigen Rapid FIV Ab/FeLV Ag Test performed very well and can be recommended for use in veterinary practice.

  16. A Novel Large-scale Mentoring Program for Medical Students based on a Quantitative and Qualitative Needs Analysis

    Science.gov (United States)

    von der Borch, Philip; Dimitriadis, Konstantinos; Störmann, Sylvère; Meinel, Felix G.; Moder, Stefan; Reincke, Martin; Tekian, Ara; Fischer, Martin R.

    2011-01-01

    Purpose: Mentoring plays an important role in students' performance and career. The authors of this study assessed the need for mentoring among medical students and established a novel large-scale mentoring program at Ludwig-Maximilians-University (LMU) Munich School of Medicine. Methods: Needs assessment was conducted using a survey distributed to all students at the medical school (n=578 of 4,109 students, return rate 14.1%). In addition, the authors held focus groups with selected medical students (n=24) and faculty physicians (n=22). All students signing up for the individual mentoring completed a survey addressing their expectations (n=534). Results: Needs assessment revealed that 83% of medical students expressed overall satisfaction with the teaching at LMU. In contrast, only 36.5% were satisfied with how the faculty supports their individual professional development and 86% of students voiced a desire for more personal and professional support. When asked to define the role of a mentor, 55.6% "very much" wanted their mentors to act as counselors, arrange contacts for them (36.4%), and provide ideas for professional development (28.1%). Topics that future mentees "very much" wished to discuss included research (56.6%), final year electives (55.8%) and experiences abroad (45.5%). Conclusions: Based on the strong desire for mentoring among medical students, the authors developed a novel two-tiered system that introduces one-to-one mentoring for students in their clinical years and offers society-based peer mentoring for pre-clinical students. One year after launching the program, more than 300 clinical students had experienced one-to-one mentoring and 1,503 students and physicians were involved in peer mentoring societies. PMID:21818236

  17. Evolution in pharmacologic thinking around the natural analgesic palmitoylethanolamide: from nonspecific resistance to PPAR-α agonist and effective nutraceutical

    Directory of Open Access Journals (Sweden)

    Keppel Hesselink JM

    2013-08-01

    Full Text Available Jan M Keppel Hesselink Department of Pharmacology, University of Witten/Herdecke, Witten, Germany Abstract: The history of development of new concepts in pharmacology is a highly interesting topic. This review discusses scientific insights related to palmitoylethanolamide (PEA and its progression over a period of six decades, especially in light of the work of the science sociologists, Ludwig Fleck and Thomas Kuhn. The discovery of the cannabis receptors and the nuclear peroxisome proliferator-activated receptors was the beginning of a completely new understanding of many important homeostatic physiologic mechanisms in the human body. These discoveries were necessary for us to understand the analgesic and anti-inflammatory activity of PEA, a body-own fatty amide. PEA is a nutrient known already for more than 50 years. PEA is synthesized and metabolized in animal cells via a number of enzymes and has a multitude of physiologic functions related to metabolic homeostasis. PEA was identified in the 1950s as a therapeutic principle with potent anti-inflammatory properties. Since 1975, its analgesic properties have been noted and explored in a variety of chronic pain states. Since 2008, PEA has been available as a nutraceutical under the brand names Normast® and PeaPure®. A literature search on PEA meanwhile has yielded over 350 papers, all referenced in PubMed, describing the physiologic properties of this endogenous modulator and its pharmacologic and therapeutic profile. This review describes the emergence of concepts related to the pharmacologic profile of PEA, with an emphasis on the search into its mechanism of action and the impact of failing to identify such mechanism in the period 1957–1993, on the acceptance of PEA as an anti-inflammatory and analgesic compound. Keywords: palmitoylethanolamide, sociology, science, paradigm, peroxisome proliferator-activated receptor-alpha, nutraceutical

  18. Thermosensitive liposomal drug delivery systems: state of the art review

    Directory of Open Access Journals (Sweden)

    Kneidl B

    2014-09-01

    Full Text Available Barbara Kneidl,1,2 Michael Peller,3 Gerhard Winter,2 Lars H Lindner,1 Martin Hossann11Department of Internal Medicine III, University Hospital Munich, 2Department of Pharmacy, Pharmaceutical Technology and Biopharmaceutics, 3Institute for Clinical Radiology, University Hospital Munich, Ludwig-Maximilians University, Munich, GermanyAbstract: Thermosensitive liposomes are a promising tool for external targeting of drugs to solid tumors when used in combination with local hyperthermia or high intensity focused ultrasound. In vivo results have demonstrated strong evidence that external targeting is superior over passive targeting achieved by highly stable long-circulating drug formulations like PEGylated liposomal doxorubicin. Up to March 2014, the Web of Science listed 371 original papers in this field, with 45 in 2013 alone. Several formulations have been developed since 1978, with lysolipid-containing, low temperature-sensitive liposomes currently under clinical investigation. This review summarizes the historical development and effects of particular phospholipids and surfactants on the biophysical properties and in vivo efficacy of thermosensitive liposome formulations. Further, treatment strategies for solid tumors are discussed. Here we focus on temperature-triggered intravascular and interstitial drug release. Drug delivery guided by magnetic resonance imaging further adds the possibility of performing online monitoring of a heating focus to calculate locally released drug concentrations and to externally control drug release by steering the heating volume and power. The combination of external targeting with thermosensitive liposomes and magnetic resonance-guided drug delivery will be the unique characteristic of this nanotechnology approach in medicine.Keywords: thermosensitive liposomes, phosphatidyloligoglycerol, hyperthermia, high intensity focused ultrasound, drug delivery, drug targeting

  19. Real time shear wave elastography in chronic liver diseases: Accuracy for predicting liver fibrosis, in comparison with serum markers

    Science.gov (United States)

    Jeong, Jae Yoon; Kim, Tae Yeob; Sohn, Joo Hyun; Kim, Yongsoo; Jeong, Woo Kyoung; Oh, Young-Ha; Yoo, Kyo-Sang

    2014-01-01

    AIM: To evaluate the correlation between liver stiffness measurement (LSM) by real-time shear wave elastography (SWE) and liver fibrosis stage and the accuracy of LSM for predicting significant and advanced fibrosis, in comparison with serum markers. METHODS: We consecutively analyzed 70 patients with various chronic liver diseases. Liver fibrosis was staged from F0 to F4 according to the Batts and Ludwig scoring system. Significant and advanced fibrosis was defined as stage F ≥ 2 and F ≥ 3, respectively. The accuracy of prediction for fibrosis was analyzed using receiver operating characteristic curves. RESULTS: Seventy patients, 15 were belonged to F0-F1 stage, 20 F2, 13 F3 and 22 F4. LSM was increased with progression of fibrosis stage (F0-F1: 6.77 ± 1.72, F2: 9.98 ± 3.99, F3: 15.80 ± 7.73, and F4: 22.09 ± 10.09, P < 0.001). Diagnostic accuracies of LSM for prediction of F ≥ 2 and F ≥ 3 were 0.915 (95%CI: 0.824-0.968, P < 0.001) and 0.913 (95%CI: 0.821-0.967, P < 0.001), respectively. The cut-off values of LSM for prediction of F ≥ 2 and F ≥ 3 were 8.6 kPa with 78.2% sensitivity and 93.3% specificity and 10.46 kPa with 88.6% sensitivity and 80.0% specificity, respectively. However, there were no significant differences between LSM and serum hyaluronic acid and type IV collagen in diagnostic accuracy. CONCLUSION: SWE showed a significant correlation with the severity of liver fibrosis and was useful and accurate to predict significant and advanced fibrosis, comparable with serum markers. PMID:25320528

  20. Without Pictorial Detour: Benjamin, Mies and the Architectural Image

    Directory of Open Access Journals (Sweden)

    Lutz Robbers

    2016-05-01

    Full Text Available It can be argued that architectural knowledge was of crucial importance to Walter Benjamin for elaborating his version of an anthropological historical materialism. Between 1929 and 1931 he encounters two publications on architectural history which had a decisive impact on his ensuing works: Sigfried Giedion’s Bauen in Frankreich, Bauen in Eisen, Bauen in Eisenbeton (1928 and Carl Linfert’s Die Grundlagen der Architekturzeichnung (1931. It can be argued that both works played a role in affirming, if not developing his historical method of awakening the dreaming collective into a ‘now of recognisability,’ a method which one can argue is based on a specific image-based epistemology. Especially the architectural image, whether in the form of a printed drawing, photographic illustration, or an actual built object, appears to have been crucial for placing the history of media technologies (architecture being one of these media in a constellation with the ‘archaic symbol-worlds of mythologies.’ If architecture is, as Benjamin claims in his initial notes for The Arcades Project, ‘the most important testimony to latent “mythology,”’ the architectural image might very well be the agent that causes the moment of awakening, the instance when a constellation between technology and ancient symbol worlds is formed. In the second part of this essay, I will attempt to elaborate such a designation for the specificity of the architectural image by analysing a number of Ludwig Mies van der Rohe’s drawings and collages from the 1920s as architectural images in the Benjaminian sense.