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Sample records for low-q instrument lqd

  1. Solutions for implementing time-of-flight techniques in low-angle neutron scattering, as realized on the Low-Q Diffractometer at Los Alamos

    International Nuclear Information System (INIS)

    Hjelm, R.P. Jr.; Seeger, P.A.

    1992-01-01

    The implementation of small-angle (Low-momentum transfer) neutron scattering at pulsed spallation sources, using time of flight methods, has meant the introduction of some new ideas in instrument design, data acquisition, data reduction and computer management of the experiment and the data. Here we recount some of the salient aspects of solutions for implementing time of fight small-angle neutron scattering instruments at pulsed sources, as realized on the Low-Q Diffractometer, LQD, at Los Alamos. We consider, fortlier, some of the problems that are yet to be solved, and take a short excursion into the future of SANS instrumentation at pulsed sources

  2. The resolution of TOF low-Q diffractometers: Instrumental, data acquisition and reduction factors

    International Nuclear Information System (INIS)

    Hjelm, R.P. Jr.

    1988-01-01

    The resolution of scattering vector, Q, in small-angle neutron scattering (SANS) measurements derives from uncertainties in scattered neutron wavelength and direction. The manner in which these are manifest on brod-band time-of-flight (TOF) spectrometers at pulsed sources is different from that for instruments using monochromated sources. In TOF instruments the uncertainties arise from the TOF measurement as well as the directional uncertainties due to collimation, finite sample and detector-element size that are present in any small-angle scattering instrument. Further, data from a TOF instrument must be mapped into Q space, and the strategy used to accomplish this affects the final resolution of the measurement. Thus for TOF-SANS instruments the question of resolution is more complicated than for instruments on monochromated sources. There is considerable flexibility in TOF data acquisition and Q mapping that can be utilized to optimize for intensity and Q resolution requirements of a particular measurement. In this work, present understanding of the effects of instrument geometry, TOF data acquisition and Q mapping strategies on the precision of the measurement is outlined. The goal is to establish guidelines on the best manner in which a particular measurement can be set up. Toward this end some new aspects are presented of optimal Q-mapping procedures, the effect of inelastic scattering on the measurement, and the calculation of instrument resolution functions. Some of these ideas are tested by comparison of simulations with measurement. (orig.)

  3. Low-T, Low-Q Cryocoolers for Science Instruments

    Data.gov (United States)

    National Aeronautics and Space Administration — The purpose of the planned research is to advance the current space science instruments through the development of light weight and low power cryocoolers. Currently,...

  4. A design for a high resolution very-low-Q time-of flight diffractometer

    International Nuclear Information System (INIS)

    Hjelm, R. P.

    1998-01-01

    The design of a high resolution view low-Q time of flight diffractometer was motivated by the anticipated need to perform small-angle neutron scattering measurements at far lower momentum transfer and higher precision than currently available at either pulsed or steady state sources. In addition, it was recognized that flexibility in the configuration of the instrument and ease in which data is acquired are important. The design offers two configurations, a high intensity/very low Q geometry employing a focusing mirror and a medium to high Q-precision/low Q configuration using standard pinhole collimation geometry. The quality of the mirror optics is very important to the performance of the high intensity/very low Q configuration. We believe that the necessary technology exists to fabricate the high quality mirror optics required for the instrument

  5. Design and implementation of low-Q diffractometers at spallation sources

    International Nuclear Information System (INIS)

    Seeger, P.A.; Hjelm, R.P.

    1993-01-01

    Low-Q diffractometers at spallation sources that use time of flight methods have been successfully implemented at several facilities, including the Los Alamos Neutron Scattering Center. The proposal to build new, more powerful, advanced spallation sources using advanced moderator concepts will provide luminosity greater than 20 times the brightest spallation source available today. These developments provide opportunity and challenge to expand the capabilities of present instruments with new designs. The authors review the use of time of flight for low-Q measurements and introduce new designs to extend the capabilities of present-day instruments. They introduce Monte Carlo methods to optimize design and simulate the performance of these instruments. The expected performance of the new instruments are compared to present day pulsed source- and reactor-based small-angle neutron scattering instruments. They review some of the new developments that will be needed to use the power of brighter sources effectively

  6. Metering instrument of quality factor Q of gravitational wave antenna

    International Nuclear Information System (INIS)

    Jia-yan, C.; Tong-ren, G.

    1982-01-01

    The quality factor, Q, of gravitational wave antenna depends on the material property as well as external conditions, such as temperature, residual pressure in vacuum tank, support type, additional loss from transducer on antenna, etc. In order to find out the relationship between the antenna Q and external conditions automatical operating in succession is required. The authors have designed and made a metering instrument for quality factor Q. The metering instrument of Q can measure Q of the metal cylinder and other bar of higher Q. It can give data of the measurement at regular intervals as desired. It can measure accurately the longitudinal fundamental mode frequency of the cylinder with a digital frequency meter record oscillating signal from metering instrument. Because the metering instrument excites free-vibration of the cylinder with free-running type and keep up the stationary amplitude for a long time. (Auth.)

  7. The Manuel Lujan, Jr. Neutron Scattering Center LANSCE experiment reports 1989 run cycle

    Energy Technology Data Exchange (ETDEWEB)

    Hyer, D.K.; DiStravolo, M.A. (comps.)

    1990-10-01

    This report contains a listing and description of experiments carried on at the LANSCE neutron scattering facility in the following areas: High Density Powder Diffraction; Neutron Powder Diffractometer, (NPD); Single Crystal Diffractometer, (SCD); Low-Q Diffractometer, (LQD); Surface Profile Analysis Reflectometer, (SPEAR); Filter Difference Spectrometer, (FDS); and Constant-Q Spectrometer.

  8. The Manuel Lujan, Jr. Neutron Scattering Center LANSCE experiment reports 1989 run cycle

    International Nuclear Information System (INIS)

    Hyer, D.K.; DiStravolo, M.A.

    1990-10-01

    This report contains a listing and description of experiments carried on at the LANSCE neutron scattering facility in the following areas: High Density Powder Diffraction; Neutron Powder Diffractometer, (NPD); Single Crystal Diffractometer, (SCD); Low-Q Diffractometer, (LQD); Surface Profile Analysis Reflectometer, (SPEAR); Filter Difference Spectrometer, (FDS); and Constant-Q Spectrometer

  9. Development of an instrument to measure the quality of documented nursing diagnoses, interventions and outcomes: the Q-DIO.

    Science.gov (United States)

    Müller-Staub, Maria; Lunney, Margaret; Odenbreit, Matthias; Needham, Ian; Lavin, Mary Ann; van Achterberg, Theo

    2009-04-01

    This paper aims to report the development stages of an audit instrument to assess standardised nursing language. Because research-based instruments were not available, the instrument Quality of documentation of nursing Diagnoses, Interventions and Outcomes (Q-DIO) was developed. Standardised nursing language such as nursing diagnoses, interventions and outcomes are being implemented worldwide and will be crucial for the electronic health record. The literature showed a lack of audit instruments to assess the quality of standardised nursing language in nursing documentation. A qualitative design was used for instrument development. Criteria were first derived from a theoretical framework and literature reviews. Second, the criteria were operationalized into items and eight experts assessed face and content validity of the Q-DIO. Criteria were developed and operationalized into 29 items. For each item, a three or five point scale was applied. The experts supported content validity and showed 88.25% agreement for the scores assigned to the 29 items of the Q-DIO. The Q-DIO provides a literature-based audit instrument for nursing documentation. The strength of Q-DIO is its ability to measure the quality of nursing diagnoses and related interventions and nursing-sensitive patient outcomes. Further testing of Q-DIO is recommended. Based on the results of this study, the Q-DIO provides an audit instrument to be used in clinical practice. Its criteria can set the stage for the electronic nursing documentation in electronic health records.

  10. Characteristics of low-q disruptions in PBX

    International Nuclear Information System (INIS)

    Kaye, S.M.; Jahns, G.L.; Morris, A.W.

    1988-06-01

    The results of this study indicate that even within the relatively narrow low-q/sub /psi// operating space, there is a continuum in the characteristics of the low-q/sub /psi// disruptions with a primary dependence on the value of . While the ideal external kink instability may give rise to the growing oscillations that lead up to the ultimate disruption, the instabilities are weighted towards the edge only at the lowest-q/sub /psi// (≤ 3) and highest . At even slightly higher q/sub /psi//, the oscillations are also seen, at the same frequency, in the interior of the plasma. The results further indicate that effects outside the scope of ideal MHD theory may play a significant role in low-q/sub /psi// disruptions. 34 refs., 19 figs

  11. Low q operations in Alcator

    International Nuclear Information System (INIS)

    Overskei, D.O.; Gondhalekar, A.; Hutchinson, I.; Pappas, D.; Parker, R.; Rice, J.; Scaturro, L.; Wolfe, S.

    1979-01-01

    The Alcator Tokamak has successfully achieved stable and routine operation in the low q[q(a) <= 2.6] high density regime. Significant increases in the total β are observed with no degradation in the energy confinement times. Strong MHD activity is suppressed by the programmed increase of the plasma current. (Auth.)

  12. Acceptance Test Procedure for New Pumping Instrumentation and Control Skid ''Q''

    International Nuclear Information System (INIS)

    KOCH, M.R.

    2000-01-01

    This Acceptance Test Procedure (ATP) provides for the inspection and testing of the new Pumping Instrumentation and Control (PIC) skid designed as ''Q''. The ATP will be performed after the construction of the PIC skid in the fabrication shop

  13. Development and validation of an instrument for measuring the quality of teamwork in teaching teams in postgraduate medical training (TeamQ).

    Science.gov (United States)

    Slootweg, Irene A; Lombarts, Kiki M J M H; Boerebach, Benjamin C M; Heineman, Maas Jan; Scherpbier, Albert J J A; van der Vleuten, Cees P M

    2014-01-01

    Teamwork between clinical teachers is a challenge in postgraduate medical training. Although there are several instruments available for measuring teamwork in health care, none of them are appropriate for teaching teams. The aim of this study is to develop an instrument (TeamQ) for measuring teamwork, to investigate its psychometric properties and to explore how clinical teachers assess their teamwork. To select the items to be included in the TeamQ questionnaire, we conducted a content validation in 2011, using a Delphi procedure in which 40 experts were invited. Next, for pilot testing the preliminary tool, 1446 clinical teachers from 116 teaching teams were requested to complete the TeamQ questionnaire. For data analyses we used statistical strategies: principal component analysis, internal consistency reliability coefficient, and the number of evaluations needed to obtain reliable estimates. Lastly, the median TeamQ scores were calculated for teams to explore the levels of teamwork. In total, 31 experts participated in the Delphi study. In total, 114 teams participated in the TeamQ pilot. The median team response was 7 evaluations per team. The principal component analysis revealed 11 factors; 8 were included. The reliability coefficients of the TeamQ scales ranged from 0.75 to 0.93. The generalizability analysis revealed that 5 to 7 evaluations were needed to obtain internal reliability coefficients of 0.70. In terms of teamwork, the clinical teachers scored residents' empowerment as the highest TeamQ scale and feedback culture as the area that would most benefit from improvement. This study provides initial evidence of the validity of an instrument for measuring teamwork in teaching teams. The high response rates and the low number of evaluations needed for reliably measuring teamwork indicate that TeamQ is feasible for use by teaching teams. Future research could explore the effectiveness of feedback on teamwork in follow up measurements.

  14. Inter-laboratory project q calibration of SANS instruments using silver behenate

    International Nuclear Information System (INIS)

    Ikram, Abarrul; Gunawan; Edy Giri, Putra; Suzuki, Jun-ichi; Knott, Robert

    2000-01-01

    The inter-laboratory project for q-calibration of SANS (small angle neutron scattering) using silver behenate was carried out among Indonesia National Nuclear Energy Agency (BATAN), Japan Atomic Energy Research Institute (JAERI) and Australian Nuclear Science and Technology Organization (ANSTO). The standard sample of silver behenate, [CH 3 (CH 2 ) 20 COOAg](AgBE), has been assessed as an international standard for the calibration of both x-ray and neutron scattering instruments. The results indicate excellent agreement for q calibration obtained among the three laboratories, BATAN, JAERI and ANSTO. (Y. Kazumata)

  15. Searching for R-parity violation at run-II of the tevatron

    International Nuclear Information System (INIS)

    Allanach, B.; Banerjee, S.; Berger, E. L.; Chertok, M.; Diaz, M. A.; Dreiner, H.; Eboli, O. J. P.; Harris, B. W.; Hewett, J.; Magro, M. B.; Mondal, N. K.; Narasimham, V. S.; Navarro, L.; Parua, N.; Porod, W.; Restrepo, D. A.; Richardson, P.; Rizzo, T.; Seymour, M. H.; Sullivan, Z.; Valle, J. W. F.; Campos, F. de

    1999-01-01

    The authors present an outlook for possible discovery of supersymmetry with broken R-parity at Run II of the Tevatron. They first present a review of the literature and an update of the experimental bounds. In turn they then discuss the following processes: (1) resonant slepton production followed by R P decay, (a) via LQD c and (b) via LLE c ; (2) how to distinguish resonant slepton production from Zprime or Wprime production; (3) resonant slepton production followed by the decay to neutralino LSP, which decays via LQD c ; (4) resonant stop production followed by the decay to a chargino, which cascades to the neutralino LSP; (5) gluino pair production followed by the cascade decay to charm squarks which decay directly via L 1 Q 2 D 1 c ; (6) squark pair production followed by the cascade decay to the neutralino LSP which decays via L 1 Q 2 D 1 c ; (7) MSSM pair production followed by the cascade decay to the LSP which decays (a) via LLE c , (b) via LQD c , and (c) via U c D c D c , respectively; and (8) top quark and top squark decays in spontaneous R P

  16. Low Q2 kaon electroproduction

    International Nuclear Information System (INIS)

    Markowitz, P.; Acha, A.

    2010-01-01

    A measurement of the H(e, e′ K + ) reaction was performed at Hall A, TJNAF as part of the hypernuclear experiment E94-107. Data was taken at very low Q 2 (~ 0.07 (GeV/c) 2 ) and W = 2.2 GeV. Kaons were detected along the direction of q-vector, the momentum transferred by the incident electron (θ CM = 6°). These measurements provide data about the Σ 0 /Λ ratio which drops rapidly with Q 2 , the angular dependence of the cross sections as Q 2 → 0, and the dependence of the cross section with respect to Q 2 ,W and θ CM . The dependence of the cross section at very forward angles has been poorly known. Available models are inadequate to describe the results. The measurement of the elementary cross section will constrain models for the elementary reaction which are inadequate to describe these results. It is also a key ingredient in the hypernuclear spectroscopy studies performed at the same kinematics. Details of the calculations and results will be shown. (author)

  17. Development and Validation of an Instrument for Measuring the Quality of Teamwork in Teaching Teams in Postgraduate Medical Training (TeamQ)

    Science.gov (United States)

    Slootweg, Irene A.; Lombarts, Kiki M. J. M. H.; Boerebach, Benjamin C. M.; Heineman, Maas Jan; Scherpbier, Albert J. J. A.; van der Vleuten, Cees P. M.

    2014-01-01

    Background Teamwork between clinical teachers is a challenge in postgraduate medical training. Although there are several instruments available for measuring teamwork in health care, none of them are appropriate for teaching teams. The aim of this study is to develop an instrument (TeamQ) for measuring teamwork, to investigate its psychometric properties and to explore how clinical teachers assess their teamwork. Method To select the items to be included in the TeamQ questionnaire, we conducted a content validation in 2011, using a Delphi procedure in which 40 experts were invited. Next, for pilot testing the preliminary tool, 1446 clinical teachers from 116 teaching teams were requested to complete the TeamQ questionnaire. For data analyses we used statistical strategies: principal component analysis, internal consistency reliability coefficient, and the number of evaluations needed to obtain reliable estimates. Lastly, the median TeamQ scores were calculated for teams to explore the levels of teamwork. Results In total, 31 experts participated in the Delphi study. In total, 114 teams participated in the TeamQ pilot. The median team response was 7 evaluations per team. The principal component analysis revealed 11 factors; 8 were included. The reliability coefficients of the TeamQ scales ranged from 0.75 to 0.93. The generalizability analysis revealed that 5 to 7 evaluations were needed to obtain internal reliability coefficients of 0.70. In terms of teamwork, the clinical teachers scored residents' empowerment as the highest TeamQ scale and feedback culture as the area that would most benefit from improvement. Conclusions This study provides initial evidence of the validity of an instrument for measuring teamwork in teaching teams. The high response rates and the low number of evaluations needed for reliably measuring teamwork indicate that TeamQ is feasible for use by teaching teams. Future research could explore the effectiveness of feedback on teamwork in

  18. Characteristics of low-q disruptions in PBX

    International Nuclear Information System (INIS)

    Kaye, S.M.; Morris, A.W.

    1988-01-01

    At low q ψ (2.3 ψ t > well below the first stability regime boundary (approx. = 2.5 μ o I p /aB t ), follows the crash of the precursor mode either immediately or with a delay of several milliseconds, with the immediate disruptions primarily occurring in the discharges with t > close to the first regime limit. The highest t > discharges also exhibit the fastest growth times and the highest level of edge MHD activity. Associated with the precursor mode crash is a loss of up to 30% of the plasma energy; thus, for non-zero delay shots, it is the crash and not the actual disruption that is the t > limiting process. The delay period is interpreted as a period during which a locked mode, consisting of several toroidal components of comparable amplitude, grows. Because of the energy loss associated with the crash, the plasma goes vertically unstable during the delay period. The results of this study indicate that even within the relatively narrow low-q ψ operating space, there is a continuum in the characteristics of the low-q ψ disruptions with a primary dependence on the value of t >. While the ideal external kink instability may give rise to the growing oscillations that lead up to the ultimate disruption, the instabilities are weighted towards the edge only at the lowest q ψ ( t >. The results of this study indicate that effects outside the scope of ideal MHD theory may play a significant role in low-q ψ disruptions. (author). 34 refs, 17 figs

  19. Test Report for Acceptance Test Procedure for Pumping Instrumentation and Control Skid Q

    International Nuclear Information System (INIS)

    KOCH, M.R.

    2000-01-01

    This Acceptance Test Report (ATR) provides the test results for the inspection and testing of the new Pumping Instrumentation and Control (PIC) skid designed as ''Q''. The ATR summaries the results and provides a copy of the ATP and inspections in the Appendix

  20. Reliability of the Q Force; a mobile instrument for measuring isometric quadriceps muscle strength.

    Science.gov (United States)

    Douma, K W; Regterschot, G R H; Krijnen, W P; Slager, G E C; van der Schans, C P; Zijlstra, W

    2016-01-01

    The ability to generate muscle strength is a pre-requisite for all human movement. Decreased quadriceps muscle strength is frequently observed in older adults and is associated with a decreased performance and activity limitations. To quantify the quadriceps muscle strength and to monitor changes over time, instruments and procedures with a sufficient reliability are needed. The Q Force is an innovative mobile muscle strength measurement instrument suitable to measure in various degrees of extension. Measurements between 110 and 130° extension present the highest values and the most significant increase after training. The objective of this study is to determine the test-retest reliability of muscle strength measurements by the Q Force in older adults in 110° extension. Forty-one healthy older adults, 13 males and 28 females were included in the study. Mean (SD) age was 81.9 (4.89) years. Isometric muscle strength of the Quadriceps muscle was assessed with the Q Force at 110° of knee extension. Participants were measured at two sessions with a three to eight day interval between sessions. To determine relative reliability, the intraclass correlation coefficient (ICC) was calculated. To determine absolute reliability, Bland and Altman Limits of Agreement (LOA) were calculated and t-tests were performed. Relative reliability of the Q Force is good to excellent as all ICC coefficients are higher than 0.75. Generally a large 95 % LOA, reflecting only moderate absolute reliability, is found as exemplified for the peak torque left leg of -18.6 N to 33.8 N and the right leg of -9.2 N to 26.4 N was between 15.7 and 23.6 Newton representing 25.2 % to 39.9 % of the size of the mean. Small systematic differences in mean were found between measurement session 1 and 2. The present study shows that the Q Force has excellent relative test-retest reliability, but limited absolute test-retest reliability. Since the Q Force is relatively cheap and mobile it is suitable for

  1. Reliability of the Q Force; a mobile instrument for measuring isometric quadriceps muscle strength

    OpenAIRE

    Schans, van der, C.P.; Zijlstra, W.; Regterschot, G.R.H.; Krijnen, W.P.; Douma, K.W.; Slager, G.E.C.

    2016-01-01

    BACKGROUND: The ability to generate muscle strength is a pre-requisite for all human movement. Decreased quadriceps muscle strength is frequently observed in older adults and is associated with a decreased performance and activity limitations. To quantify the quadriceps muscle strength and to monitor changes over time, instruments and procedures with a sufficient reliability are needed. The Q Force is an innovative mobile muscle strength measurement instrument suitable to measure in various d...

  2. Low-Q MHD activity studies on T.F.R

    International Nuclear Information System (INIS)

    1983-08-01

    T.F.R. has been operated in low q(a) conditions, with a special emphasis on the understanding of the so called current limit. Several schemes have been used, one of the most promising being magnetic surface skinning with a variable toroidal field. Detailed analysis of Mirnov coil and soft X-ray signals is presented and the results discussed. Low q(a) -i.e. high current- discharges have a high poloidal magnetic energy content, which has to be dissipated during the post-disruptive current decrease. The electromagnetic energy balance during this phase is analysed and the dissipation mechanisms identified. Consequences for large tokamaks concerning low-q operation and thermal load associated to major disruptions are deduced

  3. [Psychometric properties of Q-DIO, an instrument to measure the quality of documented nursing diagnoses, interventions and outcomes].

    NARCIS (Netherlands)

    Muller-Staub, M.; Lunney, M.; Lavin, M.A.; Needham, I.; Odenbreit, M.; Achterberg, T. van

    2010-01-01

    The instrument Q-DIO was developed in the years 2005 till 2006 to measure the quality of documented nursing diagnoses, interventions, and nursing sensitive patient outcomes. Testing psychometric properties of the Q-DIO (Quality of nursing Diagnoses, Interventions and Outcomes.) was the study aim.

  4. The proton and deuteron F2 structure function at low Q2

    International Nuclear Information System (INIS)

    Tvaskis, Vladas; Arrington, John; Asaturyan, Razmik; Baker, Oliver; Blok, Henk; Bosted, Peter; Boswell, Melissa; Bruell, Antje; Christy, Michael; Cochran, Anthony; Ent, Rolf; Filippone, Bradley; Gasparian, Ashot; Keppel, Cynthia; Kinney, Edward; Lapikas, L.; Lorenzon, Wolfgang; Mack, David; Mammei, Juliette; Martin, J.W.; Mkrtchyan, Hamlet; Niculescu, Maria-Ioana; Piercey, Rodney; Potterveld, David; Smith, Gregory; Spurlock, Kurt; Van der Steenhoven, Gerard; Stepanyan, Stepan; Tadevosyan, Vardan; Wood, Stephen

    2010-01-01

    Measurements of the proton and deuteron F2 structure functions are presented. The data, taken at Jefferson Lab Hall C, span the four-momentum transfer range 0:06 < Q2 < 2:8 GeV2, and Bjorken x values from 0.009 to 0.45, thus extending the knowledge of F2 to low values of Q2 at low x. Next-to-next-to-leading order calculations using recent parton distribution functions start to deviate from the data for Q2 < 2 GeV2 at the low and high x-values. Down to the lowest value of Q2, the structure function is in good agreement with a parameterization of F2 based on data that have been taken at much higher values of Q2 or much lower values of x, and which is constrained by data at the photon point. The ratio of the deuteron and proton structure functions at low x remains well described by a logarithmic dependence on Q2 at low Q2.

  5. Testing the Q-DIO as an instrument to measure the documented quality of nursing diagnoses, interventions, and outcomes.

    NARCIS (Netherlands)

    Muller-Staub, M.; Lunney, M.; Lavin, M.A.; Needham, I.; Odenbreit, M.; Achterberg, T. van

    2008-01-01

    PURPOSE: To describe pilot testing of Quality of Diagnoses, Interventions and Outcomes (Q-DIO), an instrument to measure quality of nursing documentation. DESIGN: Instrument testing was performed using a random, stratified sample of 60 nursing documentations representing hospital nursing with and

  6. [Psychometric properties of Q-DIO, an instrument to measure the quality of documented nursing diagnoses, interventions and outcomes].

    Science.gov (United States)

    Müller-Staub, Maria; Lunney, Margaret; Lavin, Mary Ann; Needham, Ian; Odenbreit, Matthias; van Achterberg, Theo

    2010-04-01

    The instrument Q-DIO was developed in the years 2005 till 2006 to measure the quality of documented nursing diagnoses, interventions, and nursing sensitive patient outcomes. Testing psychometric properties of the Q-DIO (Quality of nursing Diagnoses, Interventions and Outcomes.) was the study aim. Instrument testing included internal consistency, test-retest reliability, interrater reliability, item analyses, and an assessment of the objectivity. To render variation in scores, a random strata sample of 60 nursing documentations was drawn. The strata represented 30 nursing documentations with and 30 without application of theory based, standardised nursing language. Internal consistency of the subscale nursing diagnoses as process showed Cronbach's Alpha 0.83 [0.78, 0.88]; nursing diagnoses as product 0.98 [0.94, 0.99]; nursing interventions 0.90 [0.85, 0.94]; and nursing-sensitive patient outcomes 0.99 [0.95, 0.99]. With Cohen's Kappa of 0.95, the intrarater reliability was good. The interrater reliability showed a Kappa of 0.94 [0.90, 0.96]. Item analyses confirmed the fulfilment of criteria for degree of difficulty and discriminative validity of the items. In this study, Q-DIO has shown to be a reliable instrument. It allows measuring the documented quality of nursing diagnoses, interventions and outcomes with and without implementation of theory based, standardised nursing languages. Studies for further testing of Q-DIO in other settings are recommended. The results implicitly support the use of nursing classifications such as NANDA, NIC and NOC.

  7. The design and q resolution of the small and wide angle neutron scattering instrument (TAIKAN) in J-PARC

    International Nuclear Information System (INIS)

    Takata, Shin-ichi; Suzuki, Jun-ichi; Shinohara, Takenao; Oku, Takayuki; Tominaga, Taiki; Nakatani, Takeshi; Inamura, Yasuhiro; Suzuya, Kentaro; Aizawa, Kazuya; Arai, Masatoshi; Ohishi, Kazuki; Iwase, Hiroki; Ito, Takayoshi; Otomo, Toshiya; Sugiyama, Masaaki

    2015-01-01

    The small and wide angle neutron scattering instrument (TAIKAN) is designed to cover the wide q range of 0.005 0.3 Å"-"1 with the other banks. The q resolution was compared with the values experimentally obtained from the widths of Bragg peaks of a standard sample, silver behenate. The results of the experiment were consistent with the theory. It was confirmed that TAIKAN was completed as was expected. (author)

  8. Polarimetric receiver in the forty gigahertz band: new instrument for the Q-U-I joint Tenerife experiment

    Science.gov (United States)

    Villa, Enrique; Cano, Juan L.; Aja, Beatriz; Terán, J. Vicente; de la Fuente, Luisa; Mediavilla, Ángel; Artal, Eduardo

    2018-03-01

    This paper describes the analysis, design and characterization of a polarimetric receiver developed for covering the 35 to 47 GHz frequency band in the new instrument aimed at completing the ground-based Q-U-I Joint Tenerife Experiment. This experiment is designed to measure polarization in the Cosmic Microwave Background. The described high frequency instrument is a HEMT-based array composed of 29 pixels. A thorough analysis of the behaviour of the proposed receiver, based on electronic phase switching, is presented for a noise-like linearly polarized input signal, obtaining simultaneously I, Q and U Stokes parameters of the input signal. Wideband subsystems are designed, assembled and characterized for the polarimeter. Their performances are described showing appropriate results within the 35-to-47 GHz frequency band. Functionality tests are performed at room and cryogenic temperatures with adequate results for both temperature conditions, which validate the receiver concept and performance.

  9. Development and validation of an instrument for measuring the quality of teamwork in teaching teams in postgraduate medical training (TeamQ)

    NARCIS (Netherlands)

    Slootweg, Irene A.; Lombarts, Kiki M. J. M. H.; Boerebach, Benjamin C. M.; Heineman, Maas Jan; Scherpbier, Albert J. J. A.; van der Vleuten, Cees P. M.

    2014-01-01

    Teamwork between clinical teachers is a challenge in postgraduate medical training. Although there are several instruments available for measuring teamwork in health care, none of them are appropriate for teaching teams. The aim of this study is to develop an instrument (TeamQ) for measuring

  10. On Combining High and Low Q2 Information on the Polarized Parton Densities

    International Nuclear Information System (INIS)

    Leader, Elliot; Stamenov, Dimiter B.

    2000-01-01

    We draw attention to some problems in the combined use of high-Q 2 deep inelastic scattering (DIS) data and low-Q 2 hyperon β-decay data in the determination of the polarized parton densities. We explain why factorization schemes like the JET or AB schemes are the simplest in which to study the implications of the DIS parton densities for the physics of the low-Q 2 region. (author)

  11. Data reduction for neutron scattering from plutonium samples. Final report

    International Nuclear Information System (INIS)

    Seeger, P.A.

    1997-01-01

    An experiment performed in August, 1993, on the Low-Q Diffractometer (LQD) at the Manual Lujan Jr. Neutron Scattering Center (MLNSC) was designed to study the formation and annealing of He bubbles in aged 239 Pu metal. Significant complications arise in the reduction of the data because of the very high total neutron cross section of 239 Pu, and also because the sample are difficult to make uniform and to characterize. This report gives the details of the data and the data reduction procedures, presents the resulting scattering patterns in terms of macroscopic cross section as a function of momentum transfer, and suggests improvements for future experiments

  12. The thirty gigahertz instrument receiver for the Q-U-I Joint Tenerife experiment: Concept and experimental results

    Energy Technology Data Exchange (ETDEWEB)

    Villa, Enrique, E-mail: villae@unican.es; Cano, Juan L.; Cagigas, Jaime; Pérez, Ana R.; Aja, Beatriz; Terán, J. Vicente; Fuente, Luisa de la; Artal, Eduardo; Mediavilla, Ángel [Departamento Ingeniería de Comunicaciones, Universidad de Cantabria, Plaza de la Ciencia s/n, Santander 39005 (Spain); Ortiz, David; Casas, Francisco J. [Instituto de Física de Cantabria, Avda. Los Castros s/n, Santander 39005 (Spain); Hoyland, Roger [Instituto de Astrofísica de Canarias, Vía Láctea s/n, La Laguna 38205 (Spain)

    2015-02-15

    This paper presents the analysis, design, and characterization of the thirty gigahertz instrument receiver developed for the Q-U-I Joint Tenerife experiment. The receiver is aimed to obtain polarization data of the cosmic microwave background radiation from the sky, obtaining the Q, U, and I Stokes parameters of the incoming signal simultaneously. A comprehensive analysis of the theory behind the proposed receiver is presented for a linearly polarized input signal, and the functionality tests have demonstrated adequate results in terms of Stokes parameters, which validate the concept of the receiver based on electronic phase switching.

  13. The thirty gigahertz instrument receiver for the Q-U-I Joint Tenerife experiment: Concept and experimental results

    International Nuclear Information System (INIS)

    Villa, Enrique; Cano, Juan L.; Cagigas, Jaime; Pérez, Ana R.; Aja, Beatriz; Terán, J. Vicente; Fuente, Luisa de la; Artal, Eduardo; Mediavilla, Ángel; Ortiz, David; Casas, Francisco J.; Hoyland, Roger

    2015-01-01

    This paper presents the analysis, design, and characterization of the thirty gigahertz instrument receiver developed for the Q-U-I Joint Tenerife experiment. The receiver is aimed to obtain polarization data of the cosmic microwave background radiation from the sky, obtaining the Q, U, and I Stokes parameters of the incoming signal simultaneously. A comprehensive analysis of the theory behind the proposed receiver is presented for a linearly polarized input signal, and the functionality tests have demonstrated adequate results in terms of Stokes parameters, which validate the concept of the receiver based on electronic phase switching

  14. Simulations of Low-q Disruptions in the Compact Toroidal Hybrid Experiment

    Science.gov (United States)

    Howell, E. C.; Hanson, J. D.; Ennis, D. A.; Hartwell, G. J.; Maurer, D. A.

    2017-10-01

    Resistive MHD simulations of low-q disruptions in the Compact Toroidal Hybrid Device (CTH) are performed using the NIMROD code. CTH is a current-carrying stellarator used to study the effects of 3D shaping on MHD stability. Experimentally, it is observed that the application of 3D vacuum fields allows CTH to operate with edge safety factor less than 2.0. However, these low-q discharges often disrupt after peak current if the applied 3D fields are too weak. Nonlinear simulations are initialized using model VMEC equilibria representative of low-q discharges with weak vacuum transform. Initially a series of symmetry preserving island chains are excited at the q=6/5, 7/5, 8/5, and 9/5 rational surfaces. These island chains act as transport barriers preventing stochastic magnetic fields in the edge from penetrating into the core. As the simulation progresses, predominately m/n=3/2 and 4/3 instabilities are destabilized. As these instabilities grow to large amplitude they destroy the symmetry preserving islands leading to large regions of stochastic fields. A current spike and loss of core thermal confinement occurs when the innermost island chain (6/5) is destroyed. Work Supported by US-DOE Grant #DE-FG02-03ER54692.

  15. The Ostomy-Q: Development and Psychometric Validation of an Instrument to Evaluate Outcomes Associated with Ostomy Appliances.

    Science.gov (United States)

    Nafees, Beenish; Rasmussen, Mikkel; LLoyd, Andrew

    2017-01-01

    Using an ostomy appliance can affect many aspects of a person's health-related quality of life (HRQL). A 2-part, descrip- tive study was designed to develop and validate an instrument to assess quality-of-life outcomes related to ostomy ap- pliance use. Study inclusion/exclusion criteria stipulated participants should be 18 to 85 years of age, have an ileostomy or colostomy, used an appliance for a minimum of 3 months without assistance, and able to complete an online survey. All participants provided sociodemographic and clinical information. In phase 1, a literature search was conducted and existing instruments used to measure HRQL in persons with an ostomy were assessed. Subsequently, the Ostomy-Q, a 23-item, Likert-response type questionnaire, divided into 4 domains (Discreetness, Comfort, Confidence, and Social Life), was developed based on published evidence and existing ostomy-related HRQL tools. Seven (7) participants re- cruited from a manufacturer user panel took part in exploratory/cognitive qualitative interviews to refine the new quality- of-life questionnaire. In phase 2, the instrument was tested to assess item variability and conceptual structure, item-total correlation, internal consistency, test-retest reliability, sensitivity, and minimal important difference (MID) in an online validation study among 200 participants from the manufacturer's user panel (equally divided by gender, 125 [62.5%] >50 years old, 128 [64%] with an ileostomy). This exercise also included completion of the Stoma Quality of Life Question- naire and 2 domains from the Ostomy Adjustment Inventory-23 to assess convergent validity. Eighty-two (82) participants recompleted these study instruments 2 weeks later to assess test-retest reliability. Sociodemographic and clinical data were assessed using descriptive statistics; Cronbach's alpha was used for internal consistency (minimum 0.70), principle component analysis for item variability/conceptual structure, and item

  16. 3D nonlinear MHD simulations of ultra-low q plasmas

    International Nuclear Information System (INIS)

    Bonfiglio, D.; Cappello, S.; Piovan, R.; Zanotto, L.; Zuin, M.

    2008-01-01

    Magnetohydrodynamic (MHD) phenomena occurring in the ultra-low safety factor (ULq) configuration are investigated by means of 3D nonlinear MHD simulations. The ULq configuration, a screw pinch characterized by the edge safety factor q edge in the interval 0 edge edge values which are about the major rational numbers, suggesting plasma self-organization. Similar behaviour is observed in experimental ULq discharges, like those recently obtained exploiting the flexibility of the RFX-mod device. The transition of q edge from a major rational number to the next one occurs together with the development of a kink deformation of the plasma column, whose stabilization yields a nearly axisymmetric state with a rather flat q profile. Numerical simulations also show that it is possible to sustain either of the two conditions, namely, the saturated kink helical configuration and the axisymmetric one, by forcing q edge at a suitable value. Finally, the effects of this MHD phenomenology on the confinement properties of ULq plasmas are discussed.

  17. Dipole model analysis of highest precision HERA data, including very low Q"2's

    International Nuclear Information System (INIS)

    Luszczak, A.; Kowalski, H.

    2016-12-01

    We analyse, within a dipole model, the final, inclusive HERA DIS cross section data in the low χ region, using fully correlated errors. We show, that these highest precision data are very well described within the dipole model framework starting from Q"2 values of 3.5 GeV"2 to the highest values of Q"2=250 GeV"2. To analyze the saturation effects we evaluated the data including also the very low 0.35< Q"2 GeV"2 region. The fits including this region show a preference of the saturation ansatz.

  18. Narrow Q-switching pulse width and low mode-locking repetition rate Q-switched mode locking with a new coupled laser cavity

    International Nuclear Information System (INIS)

    Peng, J Y; Zheng, Y; Shen, J P; Shi, Y X

    2013-01-01

    An original diode-pumped Q-switched and mode-locked solid state Nd:GdVO 4 laser is demonstrated. The laser operates with double saturable absorbers and a new coupled laser cavity. The Q-switching envelope width is compressed to be about 15 ns and the mode-locking repetition rate is as low as 90 MHz. (paper)

  19. New-generation low-power radiation survey instruments

    International Nuclear Information System (INIS)

    Waechter, D.A.; Bjarke, G.O.; Wolf, M.A.; Trujillo, F.; Umbarger, C.J.

    1983-01-01

    A number of new, ultra-low-powered radiation instruments have recently been developed at Los Alamos. Among these are two instruments which use a novel power source to eliminate costly batteries. The newly developed gamma detecting radiac, nicknamed the Firefly, and the alpha particle detecting instrument, called the Simple Cordless Alpha Monitor, both use recent advances in miniaturization and power-saving electronics to yield devices which are small, rugged, and very power-frugal. The two instruments consume so little power that the need for batteries to run them is eliminated. They are, instead, powered by a charged capacitor which will operate the instruments for an hour or more. Both line power and mechanical sources are used to charge the storage capacitors which power the instruments

  20. Reversed-field-pinch and ultra-low-q discharges in REPUTE-2

    International Nuclear Information System (INIS)

    Inoue, N.; Yoshida, Z.; Kamada, Y.; Saito, M.; Miyamoto, K.

    1987-01-01

    Ultra-low q (ULQ) and very-low q (VLQ) discharge experiments have been done using the REPUTE-1 RFP. It was found that in these q regime, the plasma density and beta are fairly high, and the confinement property is less sensitive to the error field compared to the RFP. However, since the temperature of the REPUTE-1 discharge is limited in low value because of the small plasma current due to the small toroidal field, its magnetic Reynolds number is too small to simulate the reactor plasma behavior. The radiation barrier has not been overcome yet, and consequently the energy confinement time is very short. In order to improve these aspects of the REPUTE-1 experiment, the REPUTE-2 is designed to produce higher toroidal field of 2T. The toroidal field increases slowly to the final value as in the case of the ramp-up mode of the RFP operation. The first stage of the REPUTE-2 project will be devoted to study the confinement physics of RFP, ULQ, and VLQ. In the second stage, innovation of these configurations, such as resistive shell RFP, neutral beam current drive, and higher current density, is planned. 8 refs., 1 fig., 2 tabs

  1. QCD at low Q2 - a correspondence relation for moments of structure functions

    International Nuclear Information System (INIS)

    Schrempp, B.; Schrempp, F.

    1980-01-01

    The precocious validity of QCD predictions in deep inelastic lepton nucleon scattering and e + e - annihilation is interpreted as a signal for an underlying 'correspondence principle' relating perturbative and nonperturbative physics on the Q 2 average. Correspondence relations for nonsinglet moments of deep inelastic structure functions are formulated, discussed and successfully tested against experiment. The relations provide an independent determination of the QCD Λ-parameter from low Q 2 data in perfect agreement with results from large Q 2 analyses. (author)

  2. GVMD Model Predictions for the Low Q2 Behaviour of the Spin Structure Function g1(x,Q2) and of the DHGHY Integral I(Q2)

    International Nuclear Information System (INIS)

    Badelek, B.; Kwiecinski, J.; Ziaja, B.

    2002-01-01

    Predictions for g 1 ( x, Q 2 ) at low Q 2 are obtained in the framework of the GVMD model. contributions from both light and heavy vector mesons are evaluated. The DHGHY sum rule is employed to fix the magnitude of the light vector meson contribution to g 1 , using the Recent measurements in the region of baryonic resonances. The DHGHY moment function is calculated. Predictions are compared to the data. (author)

  3. Low-Dimensional Feature Representation for Instrument Identification

    Science.gov (United States)

    Ihara, Mizuki; Maeda, Shin-Ichi; Ikeda, Kazushi; Ishii, Shin

    For monophonic music instrument identification, various feature extraction and selection methods have been proposed. One of the issues toward instrument identification is that the same spectrum is not always observed even in the same instrument due to the difference of the recording condition. Therefore, it is important to find non-redundant instrument-specific features that maintain information essential for high-quality instrument identification to apply them to various instrumental music analyses. For such a dimensionality reduction method, the authors propose the utilization of linear projection methods: local Fisher discriminant analysis (LFDA) and LFDA combined with principal component analysis (PCA). After experimentally clarifying that raw power spectra are actually good for instrument classification, the authors reduced the feature dimensionality by LFDA or by PCA followed by LFDA (PCA-LFDA). The reduced features achieved reasonably high identification performance that was comparable or higher than those by the power spectra and those achieved by other existing studies. These results demonstrated that our LFDA and PCA-LFDA can successfully extract low-dimensional instrument features that maintain the characteristic information of the instruments.

  4. A low-complexity feed-forward I/Q imbalance compensation algorithm

    NARCIS (Netherlands)

    Moseley, N.A.; Slump, Cornelis H.

    2006-01-01

    This paper presents a low-complexity adaptive feed- forward I/Q imbalance compensation algorithm. The feed-forward so- lution has guaranteed stability. Due to its blind nature the algorithm is easily incorporated into an existing receiver design. The algorithm uses three estimators to obtain the

  5. New generation low power radiation survey instruments

    International Nuclear Information System (INIS)

    Waechter, D.A.; Bjarke, G.O.; Trujillo, F.; Umbarger, C.J.; Wolf, M.A.

    1984-01-01

    A number of new, ultra-low-powered radiation instruments have recently been developed at Los Alamos. Among these are two instruments which use a novel power source to eliminate costly batteries. The newly developed gamma detecting radiac, nicknamed the Firefly, and the alpha particle detecting instrument, called the Simple Cordless Alpha Monitor, both use recent advances in miniaturization and powersaving electronics to yield devices which are small, rugged, and very power-frugal. The two instruments consume so little power that the need for batteries to run them is eliminated. They are, instead, powered by a charged capacitor which will operate the instruments for an hour or more. Use of a capacitor as a power source eliminates many problems commonly associated with battery-operated instruments, such as having to open the case to change batteries, battery storage life, availability of batteries in the field, and some savings in weight. Both line power and mechanical sources are used to charge the storage capacitors which power the instruments

  6. Q FUNCTION AWARE OPTICAL PACKET SWITCH WITH LOW PACKET LOSS RATE

    Directory of Open Access Journals (Sweden)

    OMPAL SINGH

    2017-03-01

    Full Text Available Optical packet switching (OPS is a very promising technology for the next generation data transfer due to the very large bandwidth of the optical fiber. The success of the OPS relies heavily on design of the node architecture which supports comparatively larger buffering capacity without detiorating signal quality too much and it should provide very low packet loss probability with reasonably low average delay. In this paper, a design analysis of low complexity OPS node architecture is discussed along-with its advantages. The presented architecture support both fixed and variable length packets. The packets are stored in a single piece of fiber using the WDM technology. Physical layer analysis presented in this paper is to obtain the Q function (Bit Error Rate. Finally, the Monte Carlo simulation is done to obtain the packet loss. The average delay performance of the switch and effect of Q values on packet loss rates are discussed.

  7. Development and preliminary validation of Brace Questionnaire (BrQ: a new instrument for measuring quality of life of brace treated scoliotics

    Directory of Open Access Journals (Sweden)

    Gkoltsiou Konstantina

    2006-05-01

    Full Text Available Abstract Background The quality of life among children with idiopathic scoliosis during their adolescence has been reported to be affected by the brace itself. However, a controversy exists whether brace treated scoliotics experience a poor quality of life, thus there is a need for the development of a brace-oriented instrument, as the now-existing questionnaires that are commonly used, such as the SRS -22, take into consideration the effects of both the conservative and the surgical treatment on quality of life of scoliotic children. The aim of the present study is to assess the validity and reliability of Brace Questionnaire (BrQ, a new instrument for measuring quality of life of scoliotic adolescents who are treated conservatively with a brace. Material-method Methodology of development involved literature review, patient and health care professionals' in-depth interviews and content validity analysis on patients. A validation study was performed on 28 brace treated scoliotic children aged between 9 and 18 years old. BrQ was assessed for the following psychometric properties: item convergent validity, floor and ceiling effects, internal consistency reliability, clinical validity and responsiveness to change. Results BrQ is self administrated and developmentally appropriate for ages 9 to 18 years old and is consisted of 34 Likert-scale items associated with eight domains: general health perception, physical functioning, emotional functioning, self esteem and aesthetics, vitality, school activity, bodily pain and social functioning of scoliotic children treated conservatively with a brace. The subscales of these eight dimensions can be combined to produce a total score. Higher scores mean a better quality of life. An item convergent validity ≥ 0.40 was satisfied by all items in the present study. A satisfactory internal consistency reliability for the BrQ was recorded (Cronbach's alpha coefficient was 0.82. There were no floor or ceiling

  8. Experimental study of ultra-low q discharges in the linear Extrap L1 device

    International Nuclear Information System (INIS)

    Brunsell, P.; Karlsson, Per.

    1991-01-01

    Linear pinch discharges with combined octupole and longitudinal magnetic fields are experimentally studied in the Extrap L1 device. Plasma currents are around I p =10 kA, plasma temperautres are up to T e =50 eV and plasma densities are of the order of n=5x10 21 m -3 . The plasma equilibria are in the ultra-low q (ULQ) regime corresponding to operation with plasma currents in excess of the Kruskal-Shafranov stability limit (q less than 1). The plasma current exhibits the typical time behaviour seen in toroidal ULQ experiments; the unstable setting up phase and the step-wise decay with current levels corresponding to q-values in windows between rational values. Longitudinal plasma current generated by radial plasma diffusion is seen, with amplitudes up to 30% of the externally driven current during the initial phase of the discharge. The effect of the octupole magnetic field on the ULQ confinement is investigated. The plasma temperature increases by more than a factor of two, for the optimum octupole rod current (I v =I p ), compared to the case without octupole field. A plasma current limitation for stable operation corresponding to q bigger than 1/2 is observed, excepts for low axial magnetic field strength. In the low axial field regime, the octupole field alone provides sufficient stabilization for operation with q less than 1/2. Plasma density and temperature both increase linearly with applied axial magnetic field. The density shows a strong, approximately exponential, dependence on discharge voltage. (au)

  9. The exponent λ (x,Q ) of the proton structure function F (x, Q ) at low ...

    Indian Academy of Sciences (India)

    from the gluon (g —q¯q) and so the contribution from the quark can be neglected. In the DGLAP formalism an approximate relationship can be obtained between the gluon momentum density G(x,Q2) and the logarithmic slope of the structure function F2(x,Q2). There are several such relations [6–8] available in the literature.

  10. Measuring the Neutron and 3He Spin Structure at Low Q2

    International Nuclear Information System (INIS)

    Vince Sulkosky

    2005-01-01

    The spin structure of the nucleon has been of great interest over the past few decades. Sum rules, including the Gerasimov-Drell-Hearn (GDH), and moments of the spin structure functions are powerful tools for understanding nucleon structure. The GDH sum rule, originally derived for real photon absorption, has been generalized to nonzero Q 2 . The goal of Jefferson Lab experiment E97-110 is to perform a precise measurement of the Q 2 dependence of the generalized GDH integral and of the moments of the neutron and 3 He spin structure functions between 0.02 and 0.3 GeV 2 . This Q 2 range will allow us to test predictions of Chiral Perturbation Theory, and verify the GDH sum rule by extrapolating the integral to the real photon point. The measurement will also contribute to the understanding of nucleon resonances. The data have been taken in Hall A using a high resolution spectrometer with the addition of a septum magnet, which allowed us to access the low Q 2 region. The analysis's status, prospects and impact will be discussed

  11. Comparison of SANS instruments at reactors and pulsed sources

    International Nuclear Information System (INIS)

    Thiyagarajan, P.; Epperson, J.E.; Crawford, R.K.; Carpenter, J.M.; Hjelm, R.P. Jr.

    1992-01-01

    Small angle neutron scattering is a general purpose technique to study long range fluctuations and hence has been applied in almost every field of science for material characterization. SANS instruments can be built at steady state reactors and at the pulsed neutron sources where time-of-flight (TOF) techniques are used. The steady state instruments usually give data over small q ranges and in order to cover a large q range these instruments have to be reconfigured several times and SANS measurements have to be made. These instruments have provided better resolution and higher data rates within their restricted q ranges until now, but the TOF instruments are now developing to comparable performance. The TOF-SANS instruments, by using a wide band of wavelengths, can cover a wide dynamic q range in a single measurement. This is a big advantage for studying systems that are changing and those which cannot be exactly reproduced. This paper compares the design concepts and performances of these two types of instruments

  12. Content Validity of the Hypogonadism Impact of Symptoms Questionnaire (HIS-Q): A Patient-Reported Outcome Measure to Evaluate Symptoms of Hypogonadism.

    Science.gov (United States)

    Gelhorn, Heather L; Vernon, Margaret K; Stewart, Katie D; Miller, Michael G; Brod, Meryl; Althof, Stanley E; DeRogatis, Leonard R; Dobs, Adrian; Seftel, Allen D; Revicki, Dennis A

    2016-04-01

    Hypogonadism, or low testosterone, is a common disorder. There are currently no patient-reported outcome (PRO) instruments designed to comprehensively evaluate the symptoms of hypogonadism and to detect changes in these symptoms in response to treatment. The purpose of this study was to develop a PRO instrument, the Hypogonadism Impact of Symptoms Questionnaire (HIS-Q) and to assess its content validity. A literature review, expert clinician input, and qualitative concept elicitation with 39 male hypogonadism patients (four focus groups: n = 25; individual interviews: n = 14; mean age 52.3 ± 14.3 years) from the USA were used to develop the draft HIS-Q. Subsequent cognitive interviews (n = 29; mean age 51.5 ± 15.4 years) were used to evaluate content validity. Emergent discussion with participants yielded symptoms within the sexual, physical, energy, sleep, cognition, and mood domains. Low libido and tiredness were most commonly reported. The initial version of the HIS-Q includes 53 items that were consistently understood by the participants, who found the instrument to be relevant to their experiences with hypogonadism and comprehensive in the content coverage of symptoms. The HIS-Q is a comprehensive PRO measure of hypogonadism symptom severity in males. Its design elements, including the response options and recall period, were suitable, and content validity was confirmed.

  13. Parasitic oscillation in and suppression of a gyro BW mode in a low-Q 8 GHz gyrotron

    International Nuclear Information System (INIS)

    Muggli, P.; Tran, M.Q.; Tran, T.M.

    1991-12-01

    The parasitic oscillation of the TE o 21 gyrotron Backward Wave (gyro BW) mode is observed in a low-Q, 8 GHz TE o 011 gyrotron. Although at low power (P BW o 011 mode efficiency of less than 0.25. The parasitic oscillation is suppressed by operating the gyrotron with a negative magnetic field gradient along the electron beam, which allows the maximum efficiency to reach 0.40 and the output power to be multiplied by a factor varying from 1.4 to 1.7. The optimum efficiency curve of the TE o 011 mode indicates that the low-Q cavity behaves as a much higher Q diff cavity. Too large magnetic field gradient and α values favour the TE o 012 longitudinal mode, which oscillates in place of the TE o 011 mode and limits its maximum output power. This competitive process is responsible for the high-Q like output power. (author) 14 figs., 14 refs

  14. Multifunctional quantum dots and liposome complexes in drug delivery.

    Science.gov (United States)

    Wang, Qi; Chao, Yi-Min

    2017-09-03

    Incorporating both diagnostic and therapeutic functions into a single nanoscale system is an effective modern drug delivery strategy. Combining liposomes with semiconductor quantum dots (QDs) has great potential to achieve such dual functions, referred to in this review as a liposomal QD hybrid system (L-QD). Here we review the recent literature dealing with the design and application of L-QD for advances in bio-imaging and drug delivery. After a summary of L-QD synthesis processes and evaluation of their properties, we will focus on their multifunctional applications, ranging from in vitro cell imaging to theranostic drug delivery approaches.

  15. Multifunctional quantum dots and liposome complexes in drug delivery

    Science.gov (United States)

    Wang, Qi; Chao, Yimin

    2018-01-01

    Incorporating both diagnostic and therapeutic functions into a single nanoscale system is an effective modern drug delivery strategy. Combining liposomes with semiconductor quantum dots (QDs) has great potential to achieve such dual functions, referred to in this review as a liposomal QD hybrid system (L-QD). Here we review the recent literature dealing with the design and application of L-QD for advances in bio-imaging and drug delivery. After a summary of L-QD synthesis processes and evaluation of their properties, we will focus on their multifunctional applications, ranging from in vitro cell imaging to theranostic drug delivery approaches. PMID:28866655

  16. Neutral current cross-section measurement at low Q and high y with ...

    Indian Academy of Sciences (India)

    2012-11-11

    Nov 11, 2012 ... energy, Ee, and polar angle, θe, of the scattered electron [1]. Q2 e = 2Ee Ee ... Prabhdeep Kaur and low-energy-running (LER) samples. ... to the combined detector-level predictions from the Monte Carlo (MC) models. Good.

  17. Low-Q structure related to partially saturated pores within the reservoir beneath The Geysers area in the northern California

    Science.gov (United States)

    Matsubara, M.

    2011-12-01

    A large reservoir is located beneath The Geysers geothermal area, northern California. Seismic tomography revealed high-velocity (high-V) and low-Vp/Vs zones in the reservoir (Julian et al., 1996) and a decrease of Vp/Vs from 1991 to 1998 (Guasekera et al., 2003) owing to withdrawal of steam from the reservoir. I perform attenuation tomography in this region to investigate the state of vapor and liquid within the reservoir. The target region, 38.5-39.0°N and 122.5-123°W, covers The Geysers area. I use seismograms of 1,231 events whose focal mechanism are determined among 65,810 events recorded by the Northern California Earthquake Data Center from 2002 to 2008 in the target region. The band-pass filtered seismograms are analyzed for collecting the maximum amplitude data. There are 26 stations that have a three-component seismometer among 47 seismic stations. I use the P- and S-wave maximum amplitudes during the two seconds after the arrival of those waves in order to avoid coda effects. A total of 8,545 P- and 1,168 S-wave amplitude data for 949 earthquakes recorded at 47 stations are available for the analysis using the attenuation tomographic method derived from the velocity tomographic method (Matsubara et al., 2005, 2008) in which spatial velocity correlation and station corrections are introduced to the original code of Zhao et al. (1992). I use 3-D velocity structure obtained by Thurber et al. (2009). The initial Q value is set to 150, corresponding to the average Q of the northern California (Ford et al., 2010). At sea level, low-Q zones are found extending from the middle of the steam reservoir within the main greywacke to the south part of the reservoir. At a depth of 1 km below sea level, a low-Q zone is located solely in the southern part of the reservoir. However, at a depth of 2 km a low-Q zone is located beneath the northern part of the reservoir. At depths of 1 to 3 km a felsite batholith in the deeper portions of the reservoir, and it corresponds

  18. High density low-q discharges with D-shaped plasmas in Doublet III

    International Nuclear Information System (INIS)

    Nagami, Masayuki; Yoshida, Hidetoshi; Shinya, Kichiro; Yokomizo, Hideaki; Shimada, Michiya; Ioki, Kimihiro; Izumi, Shigeru; Kitsunezaki, Masao; Jahns, G.

    1981-07-01

    The maximum plasma current in Doublet III is found to be limited by disruptions when the limiter safety factor is approximately 2. However, due to the strong toroidal and shaping field effect on rotational transform at the outer plasma edge associated with a D-shape formation having a vertical elongation of 1.5, the safety factor q sub(a) * estimated from simple geometric considerations for D-shaped plasmas corresponds to values as low as 1.5. These discharges operate stably with considerably higher plasma current than most reactor design studies assume. These low-q discharges show excellent plasma performance: very flat spatial electron temperature progiles, high density operation with anti n sub(e)R/B sub(T) up to 7.8, and good energy confinement producing a volume average β of up to 1% with ohmic heating only. This operational regime appears to be applicable to future high β tokamaks with D-shaped cross section. (author)

  19. Demonstration of a switchable damping system to allow low-noise operation of high-Q low-mass suspension systems

    Science.gov (United States)

    Hennig, Jan-Simon; Barr, Bryan W.; Bell, Angus S.; Cunningham, William; Danilishin, Stefan L.; Dupej, Peter; Gräf, Christian; Hough, James; Huttner, Sabina H.; Jones, Russell; Leavey, Sean S.; Pascucci, Daniela; Sinclair, Martin; Sorazu, Borja; Spencer, Andrew; Steinlechner, Sebastian; Strain, Kenneth A.; Wright, Jennifer; Zhang, Teng; Hild, Stefan

    2017-12-01

    Low-mass suspension systems with high-Q pendulum stages are used to enable quantum radiation pressure noise limited experiments. Utilizing multiple pendulum stages with vertical blade springs and materials with high-quality factors provides attenuation of seismic and thermal noise; however, damping of these high-Q pendulum systems in multiple degrees of freedom is essential for practical implementation. Viscous damping such as eddy-current damping can be employed, but it introduces displacement noise from force noise due to thermal fluctuations in the damping system. In this paper we demonstrate a passive damping system with adjustable damping strength as a solution for this problem that can be used for low-mass suspension systems without adding additional displacement noise in science mode. We show a reduction of the damping factor by a factor of 8 on a test suspension and provide a general optimization for this system.

  20. Measurement of Dijet Production at Low $Q^{2}$ at HERA

    CERN Document Server

    Aktas, A.; Anthonis, T.; Asmone, A.; Babaev, A.; Backovic, S.; Bahr, J.; Baranov, P.; Barrelet, E.; Bartel, W.; Baumgartner, S.; Becker, J.; Beckingham, M.; Behnke, O.; Behrendt, O.; Belousov, A.; Berger, Ch.; Berger, N.; Berndt, T.; Bizot, J.C.; Bohme, J.; Boenig, M.O.; Boudry, V.; Bracinik, J.; Braunschweig, W.; Brisson, V.; Broker, H.B.; Brown, D.P.; Bruncko, D.; Busser, F.W.; Bunyatyan, A.; Buschhorn, G.; Bystritskaya, L.; Campbell, A.J.; Caron, S.; Cassol-Brunner, F.; Cerny, K.; Chekelian, V.; Chyla, J.; Collard, C.; Contreras, J.G.; Coppens, Y.R.; Coughlan, J.A.; Cousinou, M.C.; Cox, B.E.; Cozzika, G.; Cvach, J.; Dainton, J.B.; Dau, W.D.; Daum, K.; Delcourt, B.; Delerue, N.; Demirchyan, R.; De Roeck, A.; Desch, K.; De Wolf, E.A.; Diaconu, C.; Dingfelder, J.; Dodonov, V.; Dowell, J.D.; Dubak, A.; Duprel, C.; Eckerlin, Guenter; Efremenko, V.; Egli, S.; Eichler, R.; Eisele, F.; Ellerbrock, M.; Elsen, E.; Erdmann, M.; Erdmann, W.; Faulkner, P.J.W.; Favart, L.; Fedotov, A.; Felst, R.; Ferencei, J.; Fleischer, M.; Fleischmann, P.; Fleming, Y.H.; Flucke, G.; Flugge, G.; Fomenko, A.; Foresti, I.; Formanek, J.; Franke, G.; Frising, G.; Gabathuler, E.; Gabathuler, K.; Garvey, J.; Gassner, J.; Gayler, Joerg; Gerhards, R.; Gerlich, C.; Ghazaryan, Samvel; Goerlich, L.; Gogitidze, N.; Gorbounov, S.; Grab, C.; Grabski, V.; Grassler, H.; Greenshaw, T.; Gregori, M.; Grindhammer, Guenter; Haidt, D.; Hajduk, L.; Haller, J.; Heinzelmann, G.; Henderson, R.C.W.; Henschel, H.; Henshaw, O.; Heremans, R.; Herrera, G.; Herynek, I.; Heuer, R.D.; Hildebrandt, M.; Hiller, K.H.; Hladky, J.; Hoting, P.; Hoffmann, D.; Horisberger, R.; Hovhannisyan, A.; Ibbotson, M.; Ismail, M.; Jacquet, M.; Janauschek, L.; Janssen, X.; Jemanov, V.; Jonsson, L.; Johnson, C.; Johnson, D.P.; Jung, H.; Kant, D.; Kapichine, M.; Karlsson, M.; Katzy, J.; Keller, N.; Kennedy, J.; Kenyon, I.R.; Kiesling, Christian M.; Klein, M.; Kleinwort, C.; Kluge, T.; Knies, G.; Knutsson, A.; Koblitz, B.; Kolya, S.D.; Korbel, V.; Kostka, P.; Koutouev, R.; Kropivnitskaya, A.; Kroseberg, J.; Kuckens, J.; Kuhr, T.; Landon, M.P.J.; Lange, W.; Lastovicka, T.; Laycock, P.; Lebedev, A.; Leissner, B.; Lemrani, R.; Lendermann, V.; Levonian, S.; List, B.; Lobodzinska, E.; Loktionova, N.; Lopez-Fernandez, R.; Lubimov, V.; Lueders, H.; Luders, S.; Luke, D.; Lux, T.; Lytkin, L.; Makankine, A.; Malden, N.; Malinovski, E.; Mangano, S.; Marage, P.; Marks, J.; Marshall, R.; Martisikova, M.; Martyn, H.U.; Martyniak, J.; Maxfield, S.J.; Meer, D.; Mehta, A.; Meier, K.; Meyer, A.B.; Meyer, H.; Meyer, J.; Michine, S.; Mikocki, S.; Milcewicz, I.; Milstead, D.; Moreau, F.; Morozov, A.; Morozov, I.; Morris, J.V.; Mozer, Matthias Ulrich; Muller, K.; Murin, P.; Nagovizin, V.; Naroska, B.; Naumann, J.; Naumann, Th.; Newman, Paul R.; Niebuhr, C.; Nikitin, D.; Nowak, G.; Nozicka, M.; Olivier, B.; Olsson, J.E.; Ossoskov, G.; Ozerov, D.; Pascaud, C.; Patel, G.D.; Peez, M.; Perez, E.; Perieanu, A.; Petrukhin, A.; Pitzl, D.; Poschl, R.; Portheault, B.; Povh, B.; Raicevic, N.; Rauschenberger, J.; Reimer, P.; Reisert, B.; Risler, C.; Rizvi, E.; Robmann, P.; Roosen, R.; Rostovtsev, A.; Rurikova, Z.; Rusakov, S.; Rybicki, K.; Sankey, D.P.C.; Sauvan, E.; Schatzel, S.; Scheins, J.; Schilling, F.P.; Schleper, P.; Schmidt, S.; Schmitt, S.; Schneider, M.; Schoeffel, L.; Schoning, A.; Schroder, V.; Schultz-Coulon, H.C.; Schwanenberger, C.; Sedlak, K.; Sefkow, F.; Sheviakov, I.; Shtarkov, L.N.; Sirois, Y.; Sloan, T.; Smirnov, P.; Soloviev, Y.; South, D.; Spaskov, V.; Specka, Arnd E.; Spitzer, H.; Stamen, R.; Stella, B.; Stiewe, J.; Strauch, I.; Straumann, U.; Tasevsky, M.; Thompson, Graham; Thompson, P.D.; Tomasz, F.; Traynor, D.; Truoel, Peter; Tsipolitis, G.; Tsurin, I.; Turnau, J.; Tzamariudaki, E.; Uraev, A.; Urban, Marcel; Usik, A.; Valkar, S.; Valkarova, A.; Vallee, C.; Van Mechelen, P.; Vargas Trevino, A.; Vassiliev, S.; Vazdik, Y.; Veelken, C.; Vest, A.; Vichnevski, A.; Vinokurova, S.; Volchinski, V.; Wacker, K.; Wagner, J.; Waugh, B.; Weber, G.; Weber, R.; Wegener, D.; Werner, C.; Werner, N.; Wessels, M.; Wessling, B.; Winde, M.; Winter, G.G.; Wissing, Ch.; Woehrling, E.E.; Wunsch, E.; Yan, W.; Zacek, J.; Zalesak, J.; Zhang, Z.; Zhokin, A.; Zohrabyan, H.; Zomer, F.

    2004-01-01

    Triple differential dijet cross sections in e^\\pm p interactions are presented in the region of photon virtualities 27GeV, E_T2>5GeV, and pseudorapidities -2.5 < eta_1^*, eta_2^* <0. The measurements are made in the gamma^* p centre-of-mass frame, using an integrated luminosity of 57pb^-1. The data are compared with NLO QCD calculations and LO Monte Carlo programs with and without a resolved virtual photon contribution. NLO QCD calculations fail to describe the region of low Q^2 and low jet transverse energies, in contrast to a LO Monte Carlo generator which includes direct and resolved photon interactions with both transversely and longitudinally polarised photons. Initial and final state parton showers are tested as a mechanism for including higher order QCD effects in low E_T jet production.

  1. Open-flavor charm and bottom s q q ¯ Q ¯ and q q q ¯ Q ¯ tetraquark states

    Science.gov (United States)

    Chen, Wei; Chen, Hua-Xing; Liu, Xiang; Steele, T. G.; Zhu, Shi-Lin

    2017-06-01

    We provide comprehensive investigations for the mass spectrum of exotic open-flavor charmed/bottom s q q ¯ c ¯ , q q q ¯ c ¯ , s q q ¯ b ¯ , q q q ¯ b ¯ tetraquark states with various spin-parity assignments JP=0+,1+,2+ and 0- , 1- in the framework of QCD sum rules. In the diquark configuration, we construct the diquark-antidiquark interpolating tetraquark currents using the color-antisymmetric scalar and axial-vector diquark fields. The stable mass sum rules are established in reasonable parameter working ranges, which are used to give reliable mass predictions for these tetraquark states. We obtain the mass spectra for the open-flavor charmed/bottom s q q ¯c ¯, q q q ¯c ¯, s q q ¯b ¯, q q q ¯b ¯ tetraquark states with various spin-parity quantum numbers. In addition, we suggest searching for exotic doubly-charged tetraquarks, such as [s d ][u ¯ c ¯ ]→Ds(*)-π- in future experiments at facilities such as BESIII, BelleII, PANDA, LHCb, and CMS, etc.

  2. The Q-angle and sport

    DEFF Research Database (Denmark)

    Hahn, Thomas; Foldspang, Anders

    1997-01-01

    Quadriceps muscle contraction tends to straighten the Q angle. We expected that sports comprising a high amount of quadriceps training could be associated with low Q angles. The aim of the present study was to estimate the Q angle in athletes and to investigate its potential associations with par......Quadriceps muscle contraction tends to straighten the Q angle. We expected that sports comprising a high amount of quadriceps training could be associated with low Q angles. The aim of the present study was to estimate the Q angle in athletes and to investigate its potential associations...... with participation in sport. Three hundred and thirty-nine athletes had their Q angle measured. The mean of right-side Q angles was higher than left side, and the mean Q angle was higher in women than in men. The Q angle was positively associated with years of jogging, and negatively with years of soccer, swimming...... and sports participation at all. It is concluded that the use of Q angle measurements is questionable....

  3. Low-Q structure beneath The Geysers area in the northern California

    Science.gov (United States)

    Matsubara, M.

    2010-12-01

    A large reservoir is located beneath The Geysers geothermal area, northern California. Seismic tomography revealed high-velocity (high-V) and low-Vp/Vs zones in the reservoir (Julian et al., 1996) and a decrease of Vp/Vs from 1991 to 1998 (Guasekera et al., 2003) due to withdrawal of steam from the reservoir. I build on these earlier studies by performing the attenuation tomography in this region to investigate the Q structure. The target region, 38.5-39.0°N and 122.5-123°W, covers The Geysers area. I use seismographs of Northern California Earthquake Data Center, which recorded 1235 earthquakes with magnitude larger than 2.0 and resolved focal mechanisms from 2002 to 2008. The band-pass filtered seismographs are analyzed for collecting the maximum amplitude data. Three kinds of Butterworth band-pass filters, such as 1-3, 3-7, and 7-15, correspond to the analysis of the Q structure for 2, 5, and 10 Hz, respectively. I use the P- and S-wave maximum amplitudes between the two seconds after the arrival of those waves in order to avoid the effects by coda. A total of 8980 P- and 1086 S-wave amplitude data for 949 earthquakes recorded at 48 stations are available for the analysis using the attenuation tomographic method (Zao et al., 1996). Extremely low-Qp and Qs zones are found at the northwestern (NW) of The Geysers area at sea level. These zones are consistent with the high-Vp and Vs and low-Vp/Vs zones located at the NW part of the reservoir. The low-Qs zone extends to the southeast (SE) and with approximately 15 km length and 5 km width and has another negative peak beneath the SE part of the reservoir. This low-Qs zone is also consistent with the high-Vp and Vs regions of the reservoir characterized by a low-Vp/Vs zone. However, Qp in the SE part is slightly high. Below sea level in The Geysers reservoir, there are a main greywacke layer and a felsite layer. Above sea level, there is a greenstone melange beneath the NW extremely low-Qp and Qs region and a

  4. Conventional P-ω/Q-V Droop Control in Highly Resistive Line of Low-Voltage Converter-Based AC Microgrid

    DEFF Research Database (Denmark)

    Hou, Xiaochao; Sun, Yao; Yuan, Wenbin

    2016-01-01

    -ω/Q-V droop control is adopted in the low-voltage AC microgrid. As a result, the active power sharing among the distributed generators (DGs) is easily obtained without communication. More importantly, this study clears up the previous misunderstanding that conventional P-ω/Q-V droop control is only applicable...... to microgrids with highly inductive lines, and lays a foundation for the application of conventional droop control under different line impedances. Moreover, in order to guarantee the accurate reactive power sharing, a guide for designing Q-V droop gains is given, and virtual resistance is adopted to shape......In low-voltage converter-based alternating current (AC) microgrids with resistive distribution lines, the P-V droop with Q-f boost (VPD/FQB) is the most common method for load sharing. However, it cannot achieve the active power sharing proportionally. To overcome this drawback, the conventional P...

  5. In-house validation study of the DuPont Qualicon BAX system Q7 instrument with the BAX system PCR Assay for Salmonella (modification of AOAC Official Method 2003.09 and AOAC Research Institute Performance-Tested Method 100201).

    Science.gov (United States)

    Tice, George; Andaloro, Bridget; White, H Kirk; Bolton, Lance; Wang, Siqun; Davis, Eugene; Wallace, Morgan

    2009-01-01

    In 2006, DuPont Qualicon introduced the BAX system Q7 instrument for use with its assays. To demonstrate the equivalence of the new and old instruments, a validation study was conducted using the BAX system PCR Assay for Salmonella, AOAC Official Method 2003.09, on three food types. The foods were simultaneously analyzed with the BAX system Q7 instrument and either the U.S. Food and Drug Administration Bacteriological Analytical Manual or the U.S. Department of Agriculture-Food Safety and Inspection Service Microbiology Laboratory Guidebook reference method for detecting Salmonella. Comparable performance between the BAX system and the reference methods was observed. Of the 75 paired samples analyzed, 39 samples were positive by both the BAX system and reference methods, and 36 samples were negative by both the BAX system and reference methods, demonstrating 100% correlation. Inclusivity and exclusivity for the BAX system Q7 instrument were also established by testing 50 Salmonella strains and 20 non-Salmonella isolates. All Salmonella strains returned positive results, and all non-Salmonella isolates returned a negative response.

  6. Validation of the Spanish Version of the COPD-Q Questionnaire on COPD Knowledge.

    Science.gov (United States)

    Puente-Maestu, Luis; Chancafe-Morgan, Jorge; Calle, Myriam; Rodríguez-Hermosa, Juan L; Malo de Molina, Rosa; Ortega-González, Ángel; Fuster, Antonia; Márquez-Martín, Eduardo; Marcos, Pedro J; Ramírez, Laura; Ray, Shaunta'; Franks, Andrea

    2016-01-01

    Although recognition of the importance of educating chronic obstructive pulmonary disease (COPD) patients has grown in recent years, their understanding of this disease is not being measured due to a lack of specific instruments. The aim of this study was to validate the COPD-Q questionnaire, a 13-item instrument for determining COPD knowledge. The COPD-Q was translated and backtranslated, and subsequently submitted to logic and content validation by a group of COPD experts and 8 COPD patients. Reliability was studied in an independent group of 59 patients with severe COPD seen in the pulmonology ward or clinics of 6 hospitals in Spain (Andalusia, Baleares, Castilla-La Mancha, Galicia and Madrid). This sample was also used for other internal and external validations. The mean age of the group was approximately 70 years and their health awareness was low-to-medium. The number of correct answers was 8.3 (standard deviation: 1.9), median 8, range 3-13. Floor and ceiling effects were 0% and 1.5%, respectively. Internal consistency of the questionnaire was good (Cronbach's alpha=0.85) and reliability was also high, with a kappa coefficient >0.6 for all items and an intraclass correlation efficient of 0.84 for the total score. The 13-item COPD-Q is a valid, applicable and reliable instrument for determining patients' knowledge of COPD. Copyright © 2014 SEPAR. Published by Elsevier Espana. All rights reserved.

  7. Measurement of the proton structure function FL(x,Q2) at low x

    International Nuclear Information System (INIS)

    Aaron, F.D.; Andreev, V.

    2008-05-01

    A first measurement is reported of the longitudinal proton structure function F L (x,Q 2 ) at the ep collider HERA. It is based on inclusive deep inelastic e + p scattering cross section measurements with a positron beam energy of 27.5 GeV and proton beam energies of 920, 575 and 460 GeV. Employing the energy dependence of the cross section, F L is measured in a range of squared four-momentum transfers 12≤Q 2 ≤90 GeV 2 and low Bjorken x 0.00024≤x≤0.0036. The FL values agree with higher order QCD calculations based on parton densities obtained using cross section data previously measured at HERA. (orig.)

  8. Measurement of the proton structure function FL (x ,Q2) at low x

    Science.gov (United States)

    Aaron, F. D.; Alexa, C.; Andreev, V.; Antunovic, B.; Aplin, S.; Asmone, A.; Astvatsatourov, A.; Bacchetta, A.; Backovic, S.; Baghdasaryan, A.; Baranov, P.; Barrelet, E.; Bartel, W.; Beckingham, M.; Begzsuren, K.; Behnke, O.; Belousov, A.; Berger, N.; Bizot, J. C.; Boenig, M.-O.; Boudry, V.; Bozovic-Jelisavcic, I.; Bracinik, J.; Brandt, G.; Brinkmann, M.; Brisson, V.; Bruncko, D.; Bunyatyan, A.; Buschhorn, G.; Bystritskaya, L.; Campbell, A. J.; Cantun Avila, K. B.; Cassol-Brunner, F.; Cerny, K.; Cerny, V.; Chekelian, V.; Cholewa, A.; Contreras, J. G.; Coughlan, J. A.; Cozzika, G.; Cvach, J.; Dainton, J. B.; Daum, K.; Deák, M.; de Boer, Y.; Delcourt, B.; Del Degan, M.; Delvax, J.; De Roeck, A.; De Wolf, E. A.; Diaconu, C.; Dodonov, V.; Dossanov, A.; Dubak, A.; Eckerlin, G.; Efremenko, V.; Egli, S.; Eliseev, A.; Elsen, E.; Essenov, S.; Falkiewicz, A.; Faulkner, P. J. W.; Favart, L.; Fedotov, A.; Felst, R.; Feltesse, J.; Ferencei, J.; Finke, L.; Fleischer, M.; Fomenko, A.; Gabathuler, E.; Gayler, J.; Ghazaryan, S.; Glazov, A.; Glushkov, I.; Goerlich, L.; Goettlich, M.; Gogitidze, N.; Gouzevitch, M.; Grab, C.; Greenshaw, T.; Grell, B. R.; Grindhammer, G.; Habib, S.; Haidt, D.; Hansson, M.; Helebrant, C.; Henderson, R. C. W.; Henschel, H.; Herrera, G.; Hildebrandt, M.; Hiller, K. H.; Hoffmann, D.; Horisberger, R.; Hovhannisyan, A.; Hreus, T.; Jacquet, M.; Janssen, M. E.; Janssen, X.; Jemanov, V.; Jönsson, L.; Johnson, D. P.; Jung, A. W.; Jung, H.; Kapichine, M.; Katzy, J.; Kenyon, I. R.; Kiesling, C.; Klein, M.; Kleinwort, C.; Klimkovich, T.; Kluge, T.; Knutsson, A.; Kogler, R.; Korbel, V.; Kostka, P.; Kraemer, M.; Krastev, K.; Kretzschmar, J.; Kropivnitskaya, A.; Krüger, K.; Kutak, K.; Landon, M. P. J.; Lange, W.; Laštovička-Medin, G.; Laycock, P.; Lebedev, A.; Leibenguth, G.; Lendermann, V.; Levonian, S.; Li, G.; Lipka, K.; Liptaj, A.; List, B.; List, J.; Loktionova, N.; Lopez-Fernandez, R.; Lubimov, V.; Lucaci-Timoce, A.-I.; Lytkin, L.; Makankine, A.; Malinovski, E.; Marage, P.; Marti, Ll.; Martyn, H.-U.; Maxfield, S. J.; Mehta, A.; Meier, K.; Meyer, A. B.; Meyer, H.; Meyer, H.; Meyer, J.; Michels, V.; Mikocki, S.; Milcewicz-Mika, I.; Moreau, F.; Morozov, A.; Morris, J. V.; Mozer, M. U.; Mudrinic, M.; Müller, K.; Murín, P.; Nankov, K.; Naroska, B.; Naumann, Th.; Newman, P. R.; Niebuhr, C.; Nikiforov, A.; Nowak, G.; Nowak, K.; Nozicka, M.; Olivier, B.; Olsson, J. E.; Osman, S.; Ozerov, D.; Palichik, V.; Panagoulias, I.; Pandurovic, M.; Papadopoulou, Th.; Pascaud, C.; Patel, G. D.; Pejchal, O.; Peng, H.; Perez, E.; Petrukhin, A.; Picuric, I.; Piec, S.; Pitzl, D.; Plačakytė, R.; Polifka, R.; Povh, B.; Preda, T.; Radescu, V.; Rahmat, A. J.; Raicevic, N.; Raspiareza, A.; Ravdandorj, T.; Reimer, P.; Rizvi, E.; Robmann, P.; Roland, B.; Roosen, R.; Rostovtsev, A.; Rotaru, M.; Ruiz Tabasco, J. E.; Rurikova, Z.; Rusakov, S.; Salek, D.; Salvaire, F.; Sankey, D. P. C.; Sauter, M.; Sauvan, E.; Schmidt, S.; Schmitt, S.; Schmitz, C.; Schoeffel, L.; Schöning, A.; Schultz-Coulon, H.-C.; Sefkow, F.; Shaw-West, R. N.; Sheviakov, I.; Shtarkov, L. N.; Shushkevich, S.; Sloan, T.; Smiljanic, I.; Smirnov, P.; Soloviev, Y.; Sopicki, P.; South, D.; Spaskov, V.; Specka, A.; Staykova, Z.; Steder, M.; Stella, B.; Straumann, U.; Sunar, D.; Sykora, T.; Tchoulakov, V.; Thompson, G.; Thompson, P. D.; Toll, T.; Tomasz, F.; Tran, T. H.; Traynor, D.; Trinh, T. N.; Truöl, P.; Tsakov, I.; Tseepeldorj, B.; Tsurin, I.; Turnau, J.; Tzamariudaki, E.; Urban, K.; Valkárová, A.; Vallée, C.; Van Mechelen, P.; Vargas Trevino, A.; Vazdik, Y.; Vinokurova, S.; Volchinski, V.; Wegener, D.; Wessels, M.; Wissing, Ch.; Wünsch, E.; Yeganov, V.; Žáček, J.; Zálešák, J.; Zhang, Z.; Zhelezov, A.; Zhokin, A.; Zhu, Y. C.; Zimmermann, T.; Zohrabyan, H.; Zomer, F.; H1 Collaboration

    2008-07-01

    A first measurement is reported of the longitudinal proton structure function FL (x ,Q2) at the ep collider HERA. It is based on inclusive deep inelastic e+ p scattering cross section measurements with a positron beam energy of 27.5 GeV and proton beam energies of 920, 575 and 460 GeV. Employing the energy dependence of the cross section, FL is measured in a range of squared four-momentum transfers 12 ⩽Q2 ⩽ 90 GeV2 and low Bjorken x 0.00024 ⩽ x ⩽ 0.0036. The FL values agree with higher order QCD calculations based on parton densities obtained using cross section data previously measured at HERA.

  9. q-Space Upsampling Using x-q Space Regularization.

    Science.gov (United States)

    Chen, Geng; Dong, Bin; Zhang, Yong; Shen, Dinggang; Yap, Pew-Thian

    2017-09-01

    Acquisition time in diffusion MRI increases with the number of diffusion-weighted images that need to be acquired. Particularly in clinical settings, scan time is limited and only a sparse coverage of the vast q -space is possible. In this paper, we show how non-local self-similar information in the x - q space of diffusion MRI data can be harnessed for q -space upsampling. More specifically, we establish the relationships between signal measurements in x - q space using a patch matching mechanism that caters to unstructured data. We then encode these relationships in a graph and use it to regularize an inverse problem associated with recovering a high q -space resolution dataset from its low-resolution counterpart. Experimental results indicate that the high-resolution datasets reconstructed using the proposed method exhibit greater quality, both quantitatively and qualitatively, than those obtained using conventional methods, such as interpolation using spherical radial basis functions (SRBFs).

  10. International multiphase mixed methods study protocol to develop a cross-cultural patient-reported outcome instrument for children and young adults with cleft lip and/or palate (CLEFT-Q).

    Science.gov (United States)

    Wong Riff, Karen W Y; Tsangaris, Elena; Goodacre, Tim; Forrest, Christopher R; Pusic, Andrea L; Cano, Stefan J; Klassen, Anne F

    2017-01-11

    Patient-reported outcome (PRO) instruments should be developed according to rigorous guidelines in order to provide clinically meaningful, scientifically sound measurement. Understanding the methodology behind instrument development informs the selection of the most appropriate tool. This mixed methods protocol describes the development of an internationally applicable PRO instrument, the CLEFT-Q, for evaluating outcomes of treatment for cleft lip and/or palate (CL/P). The study includes three main phases that occur iteratively and interactively. In phase I, we determine what concepts are important to patients regarding their outcome. A conceptual framework for the CLEFT-Q is formed through a systematic review and an extensive international qualitative study. The systematic review ascertains what concepts have previously been measured in patients with CL/P. The qualitative study employs interpretive description and involves in-depth interviews with patients in high-income and lower-middle income countries. Preliminary items are generated from the qualitative data. Preliminary scales are then created for each theme in the framework. Cognitive debriefing interviews and expert clinician input are used to refine the scales in an iterative process. In phase II, the preliminary scales are administered to a large international group of patients with CL/P. The modern psychometric method of Rasch Measurement Theory analysis is employed to define the measurement characteristics. The preliminary scales are shortened based on these results. In phase III, further tests assess reliability, validity and responsiveness of the instrument. The study is approved by Research Ethics Boards for each participating site. Findings from this study will be published in open access peer-reviewed journals and presented at national and international conferences. Integrated knowledge translation is employed to engage stakeholders from the outset of the study. Successful execution of the CLEFT-Q

  11. Small-angle scattering instruments on a 1 MW long pulse spallation source

    Energy Technology Data Exchange (ETDEWEB)

    Olah, G.A. [Los Alamos National Lab., Chemical Science and Tehcnology Div., Biosciences and Biotechnology Group, Los aalamos, NM (United States); Hjelm, R.P. [Los Alamos National Lab., Neutron Scattering Center, Los Alamos, NM (United States); Seeger, P.A.

    1995-11-01

    We have designed and optimized two small-angle neutron scattering instruments for installation at a 1 MW long pulse spallation source. The first of these instruments measures a Q-domain from 0.002 to 0.44 A{sup -1}, and the second instrument from 0.00069-0.17 A{sup -1}, Design characteristics were determined and optimization was done using a Monte Carlo instrument simulation package under development at Los alamos. A performance comparison was made between these instruments with D11 at the ILL by evaluating the scattered intensity and rms resolution for the instrument response function at different Q values for various instrument configurations needed to spn a Q-range of 0.0007-0.44 A{sup -1}. We concluded that the first of these instruments outperforms D11 in both intensity and resolution over most of the Q-domain and that the second is comparable to D11. Comparisons were also made of the performance of the optimized long pulse instruments with different reflectors and with a short pulse source, from which we concluded that there is an optimal moderator-reflector combination, and that a short pulse does not substantially improve the instrument performance. (author) 7 figs., 2 tabs., 9 refs.

  12. Small-angle scattering instruments on a 1 MW long pulse spallation source

    International Nuclear Information System (INIS)

    Olah, G.A.; Hjelm, R.P.; Seeger, P.A.

    1995-01-01

    We have designed and optimized two small-angle neutron scattering instruments for installation at a 1 MW long pulse spallation source. The first of these instruments measures a Q-domain from 0.002 to 0.44 A -1 , and the second instrument from 0.00069-0.17 A -1 , Design characteristics were determined and optimization was done using a Monte Carlo instrument simulation package under development at Los alamos. A performance comparison was made between these instruments with D11 at the ILL by evaluating the scattered intensity and rms resolution for the instrument response function at different Q values for various instrument configurations needed to spn a Q-range of 0.0007-0.44 A -1 . We concluded that the first of these instruments outperforms D11 in both intensity and resolution over most of the Q-domain and that the second is comparable to D11. Comparisons were also made of the performance of the optimized long pulse instruments with different reflectors and with a short pulse source, from which we concluded that there is an optimal moderator-reflector combination, and that a short pulse does not substantially improve the instrument performance. (author) 7 figs., 2 tabs., 9 refs

  13. Tsallis’ quantum q-fields

    Science.gov (United States)

    Plastino, A.; Rocca, M. C.

    2018-05-01

    We generalize several well known quantum equations to a Tsallis’ q-scenario, and provide a quantum version of some classical fields associated with them in the recent literature. We refer to the q-Schródinger, q-Klein-Gordon, q-Dirac, and q-Proca equations advanced in, respectively, Phys. Rev. Lett. 106, 140601 (2011), EPL 118, 61004 (2017) and references therein. We also introduce here equations corresponding to q-Yang-Mills fields, both in the Abelian and non-Abelian instances. We show how to define the q-quantum field theories corresponding to the above equations, introduce the pertinent actions, and obtain equations of motion via the minimum action principle. These q-fields are meaningful at very high energies (TeV scale) for q = 1.15, high energies (GeV scale) for q = 1.001, and low energies (MeV scale) for q = 1.000001 [Nucl. Phys. A 955 (2016) 16 and references therein]. (See the ALICE experiment at the LHC). Surprisingly enough, these q-fields are simultaneously q-exponential functions of the usual linear fields’ logarithms.

  14. Conventional P-ω/Q-V Droop Control in Highly Resistive Line of Low-Voltage Converter-Based AC Microgrid

    Directory of Open Access Journals (Sweden)

    Xiaochao Hou

    2016-11-01

    Full Text Available In low-voltage converter-based alternating current (AC microgrids with resistive distribution lines, the P-V droop with Q-f boost (VPD/FQB is the most common method for load sharing. However, it cannot achieve the active power sharing proportionally. To overcome this drawback, the conventional P-ω/Q-V droop control is adopted in the low-voltage AC microgrid. As a result, the active power sharing among the distributed generators (DGs is easily obtained without communication. More importantly, this study clears up the previous misunderstanding that conventional P-ω/Q-V droop control is only applicable to microgrids with highly inductive lines, and lays a foundation for the application of conventional droop control under different line impedances. Moreover, in order to guarantee the accurate reactive power sharing, a guide for designing Q-V droop gains is given, and virtual resistance is adopted to shape the desired output impedance. Finally, the effects of power sharing and transient response are verified through simulations and experiments in converter-based AC Microgrid.

  15. Tailoring the High-Q LC Filter Arrays for Readout of Kilo-Pixel TES Arrays in the SPICA-SAFARI Instrument

    Science.gov (United States)

    Bruijn, M. P.; Gottardi, L.; den Hartog, R. H.; van der Kuur, J.; van der Linden, A. J.; Jackson, B. D.

    2014-08-01

    Following earlier presentations of arrays of high quality factor (Q 10.000) superconducting resonators in the MHz regime, we report on improvement of the packing density of resonance frequencies to 160 in the 1-3 MHz band. Spread in the spacing of resonances is found to be limited to 1 kHz (1 with the present fabrication procedure. The present packing density of frequencies and chip area approaches the requirements for the SAFARI instrument on the SPICA mission (in preparation). The a-Si:H dielectric layer in the planar S-I-S capacitors shows a presently unexplained apparent negative effective series resistance, depending on operating temperature and applied testing voltage.

  16. Intercomparison of NO3 radical detection instruments in the atmosphere simulation chamber SAPHIR

    Directory of Open Access Journals (Sweden)

    H.-P. Dorn

    2013-05-01

    Full Text Available The detection of atmospheric NO3 radicals is still challenging owing to its low mixing ratios (≈ 1 to 300 pptv in the troposphere. While long-path differential optical absorption spectroscopy (DOAS has been a well-established NO3 detection approach for over 25 yr, newly sensitive techniques have been developed in the past decade. This publication outlines the results of the first comprehensive intercomparison of seven instruments developed for the spectroscopic detection of tropospheric NO3. Four instruments were based on cavity ring-down spectroscopy (CRDS, two utilised open-path cavity-enhanced absorption spectroscopy (CEAS, and one applied "classical" long-path DOAS. The intercomparison campaign "NO3Comp" was held at the atmosphere simulation chamber SAPHIR in Jülich (Germany in June 2007. Twelve experiments were performed in the well-mixed chamber for variable concentrations of NO3, N2O5, NO2, hydrocarbons, and water vapour, in the absence and in the presence of inorganic or organic aerosol. The overall precision of the cavity instruments varied between 0.5 and 5 pptv for integration times of 1 s to 5 min; that of the DOAS instrument was 9 pptv for an acquisition time of 1 min. The NO3 data of all instruments correlated excellently with the NOAA-CRDS instrument, which was selected as the common reference because of its superb sensitivity, high time resolution, and most comprehensive data coverage. The median of the coefficient of determination (r2 over all experiments of the campaign (60 correlations is r2 = 0.981 (quartile 1 (Q1: 0.949; quartile 3 (Q3: 0.994; min/max: 0.540/0.999. The linear regression analysis of the campaign data set yielded very small intercepts (median: 1.1 pptv; Q1/Q3: −1.1/2.6 pptv; min/max: −14.1/28.0 pptv, and the slopes of the regression lines were close to unity (median: 1.01; Q1/Q3: 0.92/1.10; min/max: 0.72/1.36. The deviation of individual regression slopes from unity was always within the combined

  17. Extraction of the missing low-Q data from small-angle scattering data

    International Nuclear Information System (INIS)

    Doherty, G.K.; Poland, G.A.

    1996-01-01

    A new method is presented that recovers the scatter intensity curve at low Q values from small-angle neutron scattering data. The method uses only the measured data, requiring no extrapolation of the scatter curve nor any a priori knowledge of the maximum chord length, radius of gyration or molecular weight of the particle under investigation. It is assumed that the incoherent level would have been extracted from the data in the normal course of events but any errors do not affect the method presented. The distance distribution function of any particle has a restricted extension in real space and any nonzero value beyond the maximum size of the particle is due to the effects of missing data segments and noise on the measured data. The effects due to the missing and noisy data are isolated from the distance distribution of the particle and a suitably scaled template particle is used to fill in the missing distribution data segment. The inverse transform of the new distribution function returns the missing low-Q scatter data and to some extent cancels out the noise. While the method is generally explored using noise-free analytically derived particles, its application to real experimental data is demonstrated. (orig.)

  18. Can we measure patients' perception during dental impressions? The Burdens in Dental Impression-Making Questionnaire - BiDIM-Q.

    Science.gov (United States)

    Tsirogiannis, Panagiotis; Neophytou, Sophia; Reul, Anika; Heydecke, Guido; Reissmann, Daniel R

    2017-01-01

    To develop a reliable and valid instrument for the comprehensive assessment of patients' burdens during dental impression making, the Burdens in Dental Impression Making Questionnaire, BiDIM-Q. The item pool was generated in a convenience sample of 20 prosthodontic patients using semi-structured face-to-face interviews. The final instrument was tested in 145 consecutively recruited patients, and psychometric properties of the BiDIM-Q were determined. Four different impression materials were used according to the manufacturers' instructions and indications: alginate, c-silicone, polyvinylsiloxane, and polyether. The final BiDIM-Q consisting of 12 items showed sufficient reliability, indicated by Cronbach's alpha of .82 and an average inter-item correlation of .29. Validity was supported by Pearson correlation coefficients for the correlation between the instrument's total score with the patients' overall satisfaction rating (r=.63), and by the correlation matrix for the correlations of the patients' perceptions with the practitioners' satisfaction ratings. Overall, patient perceived burdens were low with highest burdens observed when using polyether in partially dentate patients for pick-up impressions, while lowest burdens were reported when using c-silicone for impressions of edentulous jaws. The BiDIM-Q is a reliable and valid tool for assessing patient-based process-related quality of care in dentistry allowing a deeper insight into patients' perspective during dental impression making. Copyright © 2016 Japan Prosthodontic Society. Published by Elsevier Ltd. All rights reserved.

  19. Group Delay of High Q Antennas

    DEFF Research Database (Denmark)

    Bahramzy, Pevand; Pedersen, Gert Frølund

    2013-01-01

    Group Delay variations versus frequency is an essential factor which can cause distortion and degradation in the signals. Usually this is an issue in wideband communication systems, such as satellite communication systems, which are used for transmitting wideband data. However, group delay can also...... become an issue, when working with high Q antennas, because of the steep phase shift over the frequency. In this paper, it is measured how large group delay variations can become, when going from a low Q antenna to a high Q antenna. The group delay of a low Q antenna is shown to be around 1.3 ns, whereas...... a high Q antenna has group delay of around 22 ns. It is due to this huge group delay variation characteristics of high Q antennas, that signal distortion might occur in the radio system with high Q antennas....

  20. Additive enhancement of wound healing in diabetic mice by low level light and topical CoQ10

    Science.gov (United States)

    Mao, Zhigang; Wu, Jeffrey H.; Dong, Tingting; Wu, Mei X.

    2016-02-01

    Diabetes, a highly prevalent disease that affects 9.3% of Americans, often leads to severe complications and slow wound healing. Preclinical studies have suggested that low level light therapy (LLLT) can accelerate wound healing in diabetic subjects, but significant improvements must be made to overcome the absence of persuasive evidence for its clinical use. We demonstrate here that LLLT can be combined with topical Coenzyme Q10 (CoQ10) to heal wounds in diabetic mice significantly faster than LLLT alone, CoQ10 alone, or controls. LLLT followed by topical CoQ10 enhanced wound healing by 68~103% in diabetic mice in the first week and more than 24% in the second week compared with untreated controls. All wounds were fully healed in two weeks following the dual treatment, in contrast to only 50% wounds or a fewer being fully healed for single or sham treatment. The accelerated healing was corroborated by at least 50% higher hydroxyproline levels, and tripling cell proliferation rates in LLLT and CoQ10 treated wounds over controls. The beneficial effects on wound healing were probably attributed to additive enhancement of ATP production by LLLT and CoQ10 treatment. The combination of LLLT and topical CoQ10 is safe and convenient, and merits further clinical study.

  1. Additive enhancement of wound healing in diabetic mice by low level light and topical CoQ10.

    Science.gov (United States)

    Mao, Zhigang; Wu, Jeffrey H; Dong, Tingting; Wu, Mei X

    2016-02-02

    Diabetes, a highly prevalent disease that affects 9.3% of Americans, often leads to severe complications and slow wound healing. Preclinical studies have suggested that low level light therapy (LLLT) can accelerate wound healing in diabetic subjects, but significant improvements must be made to overcome the absence of persuasive evidence for its clinical use. We demonstrate here that LLLT can be combined with topical Coenzyme Q10 (CoQ10) to heal wounds in diabetic mice significantly faster than LLLT alone, CoQ10 alone, or controls. LLLT followed by topical CoQ10 enhanced wound healing by 68~103% in diabetic mice in the first week and more than 24% in the second week compared with untreated controls. All wounds were fully healed in two weeks following the dual treatment, in contrast to only 50% wounds or a fewer being fully healed for single or sham treatment. The accelerated healing was corroborated by at least 50% higher hydroxyproline levels, and tripling cell proliferation rates in LLLT and CoQ10 treated wounds over controls. The beneficial effects on wound healing were probably attributed to additive enhancement of ATP production by LLLT and CoQ10 treatment. The combination of LLLT and topical CoQ10 is safe and convenient, and merits further clinical study.

  2. Measurement of the Q^{2} Dependence of the Deuteron Spin Structure Function g_{1} and its Moments at Low Q^{2} with CLAS.

    Science.gov (United States)

    Adhikari, K P; Deur, A; El Fassi, L; Kang, H; Kuhn, S E; Ripani, M; Slifer, K; Zheng, X; Adhikari, S; Akbar, Z; Amaryan, M J; Avakian, H; Ball, J; Balossino, I; Barion, L; Battaglieri, M; Bedlinskiy, I; Biselli, A S; Bosted, P; Briscoe, W J; Brock, J; Bültmann, S; Burkert, V D; Thanh Cao, F; Carlin, C; Carman, D S; Celentano, A; Charles, G; Chen, J-P; Chetry, T; Choi, S; Ciullo, G; Clark, L; Cole, P L; Contalbrigo, M; Crede, V; D'Angelo, A; Dashyan, N; De Vita, R; De Sanctis, E; Defurne, M; Djalali, C; Dodge, G E; Drozdov, V; Dupre, R; Egiyan, H; El Alaoui, A; Elouadrhiri, L; Eugenio, P; Fedotov, G; Filippi, A; Ghandilyan, Y; Gilfoyle, G P; Golovatch, E; Gothe, R W; Griffioen, K A; Guidal, M; Guler, N; Guo, L; Hafidi, K; Hakobyan, H; Hanretty, C; Harrison, N; Hattawy, M; Heddle, D; Hicks, K; Holtrop, M; Hyde, C E; Ilieva, Y; Ireland, D G; Isupov, E L; Jenkins, D; Jo, H S; Johnston, S C; Joo, K; Joosten, S; Kabir, M L; Keith, C D; Keller, D; Khachatryan, G; Khachatryan, M; Khandaker, M; Kim, W; Klein, A; Klein, F J; Konczykowski, P; Kovacs, K; Kubarovsky, V; Lanza, L; Lenisa, P; Livingston, K; Long, E; MacGregor, I J D; Markov, N; Mayer, M; McKinnon, B; Meekins, D G; Meyer, C A; Mineeva, T; Mirazita, M; Mokeev, V; Movsisyan, A; Munoz Camacho, C; Nadel-Turonski, P; Niculescu, G; Niccolai, S; Osipenko, M; Ostrovidov, A I; Paolone, M; Pappalardo, L; Paremuzyan, R; Park, K; Pasyuk, E; Payette, D; Phelps, W; Phillips, S K; Pierce, J; Pogorelko, O; Poudel, J; Price, J W; Prok, Y; Protopopescu, D; Raue, B A; Rizzo, A; Rosner, G; Rossi, P; Sabatié, F; Salgado, C; Schumacher, R A; Sharabian, Y G; Shigeyuki, T; Simonyan, A; Skorodumina, Iu; Smith, G D; Sparveris, N; Sokhan, D; Stepanyan, S; Strakovsky, I I; Strauch, S; Sulkosky, V; Taiuti, M; Tan, J A; Ungaro, M; Voutier, E; Wei, X; Weinstein, L B; Zhang, J; Zhao, Z W

    2018-02-09

    We measured the g_{1} spin structure function of the deuteron at low Q^{2}, where QCD can be approximated with chiral perturbation theory (χPT). The data cover the resonance region, up to an invariant mass of W≈1.9  GeV. The generalized Gerasimov-Drell-Hearn sum, the moment Γ_{1}^{d} and the spin polarizability γ_{0}^{d} are precisely determined down to a minimum Q^{2} of 0.02  GeV^{2} for the first time, about 2.5 times lower than that of previous data. We compare them to several χPT calculations and models. These results are the first in a program of benchmark measurements of polarization observables in the χPT domain.

  3. Role of low order rational q values on the ITB-events in JT-60U plasmas

    International Nuclear Information System (INIS)

    Neudatchin, S.V.; Takizuka, T.; Hayashi, N.; Shirai, H.; Fujita, T.; Isayama, A.; Kamada, Y.; Koide, Y.; Suzuki, T.

    2003-01-01

    The formation of internal transport barriers (ITBs) near q=2,3 surfaces in normal (NrS) or optimized shear discharges of JT-60U and JET is well known. In reverse shear (RS) JT-60U plasmas, the role of q minimum (q min ) equal to 3, 5, 3, 2, 5, 2 is not obvious for ITB formation. ITB-events (non-local confinement bifurcations inside and around ITB in a ms timescale) are found in various JT-60U NrS and RS plasmas. Under sufficient power, ITB-events are seen at rational and not rational values of q min . The space-time evolution of T e and T i is similar even being strongly varied in space and time, suggesting same mechanism(s) of T e and T i transport. The temporal formation of strong ITB in H-mode under passing of q min =3 (after periodical improvements and degradations via ITB-events with 8ms period) in RS mode with P nbi =8MW is presented. Under smaller power, ITB-events are observed only at rational values of q min . In a weak RS shot with P nbi =4MW, abrupt rise of T e is seen at q min =3.5, while more cases of T i rise are observed. The difference of the T e and T i evolution seen regularly under the low power, suggests decoupling of T e and T i transport. (author)

  4. Multisite Semiautomated Clinical Data Repository for Duplication 15q Syndrome: Study Protocol and Early Uses.

    Science.gov (United States)

    Ajayi, Oluwaseun Jessica; Smith, Ebony Jeannae; Viangteeravat, Teeradache; Huang, Eunice Y; Nagisetty, Naga Satya V Rao; Urraca, Nora; Lusk, Laina; Finucane, Brenda; Arkilo, Dimitrios; Young, Jennifer; Jeste, Shafali; Thibert, Ronald; Reiter, Lawrence T

    2017-10-18

    Chromosome 15q11.2-q13.1 duplication syndrome (Dup15q syndrome) is a rare disorder caused by duplications of chromosome 15q11.2-q13.1, resulting in a wide range of developmental disabilities in affected individuals. The Dup15q Alliance is an organization that provides family support and promotes research to improve the quality of life of patients living with Dup15q syndrome. Because of the low prevalence of this condition, the establishment of a single research repository would have been difficult and more time consuming without collaboration across multiple institutions. The goal of this project is to establish a national deidentified database with clinical and survey information on individuals diagnosed with Dup15q syndrome. The development of a multiclinic site repository for clinical and survey data on individuals with Dup15q syndrome was initiated and supported by the Dup15q Alliance. Using collaborative workflows, communication protocols, and stakeholder engagement tools, a comprehensive database of patient-centered information was built. We successfully established a self-report populating, centralized repository for Dup15q syndrome research. This repository also resulted in the development of standardized instruments that can be used for other studies relating to developmental disorders. By standardizing the data collection instruments, it allows us integrate our data with other national databases, such as the National Database for Autism Research. A substantial portion of the data collected from the questionnaires was facilitated through direct engagement of participants and their families. This allowed for a more complete set of information to be collected with a minimal turnaround time. We developed a repository that can efficiently be mined for shared clinical phenotypes observed at multiple clinic sites and used as a springboard for future clinical and basic research studies. ©Oluwaseun Jessica Ajayi, Ebony Jeannae Smith, Teeradache Viangteeravat

  5. The use of contrast variation in small angle neutron scattering on the low-Q diffractometer at the Manuel Lujuan Jr. Neutron Scattering Center at Los Alamos National Laboratory (LANSCE)

    International Nuclear Information System (INIS)

    Spaccavento, J.

    1993-01-01

    As a Department of Energy Teacher Research Associate at Los Alamos National Laboratory this past summer, the author was given the opportunity to exit the class-room and enter the world of intense scientific research for an eight week period. In this paper the author briefly describes the Manual Lujan Jr. Neutron Scattering Center at Los Alamos, then focuses specifically on the Low-Q Diffractometer which was the instrument he worked on. The author details one specific experimental technique namely open-quotes Contrast Variation,close quotes and closes by briefly presenting several other interesting applications of neutron scattering

  6. Measurement of D*± production at low Q2 with the beam-pipe calorimeter of ZEUS at HERA

    International Nuclear Information System (INIS)

    Irrgang, P.

    2004-12-01

    The production of D* mesons in deep-inelastic ep-scattering has been studied using the ZEUS detector at HERA. The total D* production cross-section and the differential cross-sections as functions of Q 2 , y, p t (D*) and η(D*) have been measured at low Q 2 . The data sample used was collected during the period 1998-2000 and amounts to an integrated luminosity of 82.2 pb -1 . The low Q 2 region could be reached using the beam-pipe calorimeter which measures the scattered electron at very small angles. Therefore special emphasis was put on the calibration of the BPC in order to reconstruct events in the kinematic range 0.05 2 2 and 0.02 * +→K - π + π - and the charged conjugated decay in the kinematic region 1.5 t (D*) 2 in agreement with the corresponding perturbative QCD predictions. (orig.)

  7. Breeding of Coenzyme Q10 Produced Strain by Low-Energy Ion Implantation and Optimization of Coenzyme Q10 Fermentation

    International Nuclear Information System (INIS)

    Xu Dejun; Zheng Zhiming; Wang Peng; Wang Li; Yuan Hang; Yu Zengliang

    2008-01-01

    In order to increase the production efficiency of coenzyme Q 10 , the original strain Agrobacterium tumefaciens ATCC 4452 was mutated by means of Nitrogen ions implantation. A mutant strain, ATX 12, with high contents of coenzyme Q 10 was selected. Subsequently, the conditions such as carbohydrate concentration, nitrogen source concentration, inoculum's size, seed age, aeration and temperature which might affect the production of CoQ 10 were investigated in detail. Under optimal conditions, the maximum concentration of the intracellular CoQ 10 reached 200.3 mg/L after 80 h fed-batch fermentation, about 245% increasing in CoQ 10 production after ion implantation, compared to the original strain. (ion beam bioengineering)

  8. Development and psychometric properties of the Shared Decision Making Questionnaire--physician version (SDM-Q-Doc).

    Science.gov (United States)

    Scholl, Isabelle; Kriston, Levente; Dirmaier, Jörg; Buchholz, Angela; Härter, Martin

    2012-08-01

    To develop and psychometrically test a brief instrument for assessing the physician's perspective of the shared decision-making process in clinical encounters. We adapted the 9-item Shared Decision Making Questionnaire (SDM-Q-9) for patients to generate a new version for physicians (SDM-Q-Doc). The physician version was tested in clinical encounters between 29 physicians and 324 patients in German outpatient care contexts. Analyses of the extent to which the instrument was accepted, the reliability of the instrument, and the factorial structure of the scale were performed. Physicians showed a high level of acceptance toward the SDM-Q-Doc. Item discrimination parameters were above .4 for all but one item. An analysis of internal consistency yielded a Cronbach's α of .88. Factor analysis confirmed a one-dimensional structure. The results of this study suggest that the SDM-Q-Doc is a well-accepted and reliable instrument for assessing the physician's perspective during SDM processes in clinical encounters. To our knowledge, the SDM-Q-Doc is the first psychometrically tested scale available for assessing the physician's perspective. The SDM-Q-Doc can be used in studies that analyze the effectiveness of the implementation of SDM and as a quality indicator in quality assurance programs and health service assessments. Copyright © 2012 Elsevier Ireland Ltd. All rights reserved.

  9. Measurement of the Inclusive ep Scattering Cross Section at Low Q^2 and x at HERA

    CERN Document Server

    Aaron, F.D.; Andreev, V.; Antunovic, B.; Aplin, S.; Asmone, A.; Astvatsatourov, A.; Backovic, S.; Baghdasaryan, A.; Barrelet, E.; Bartel, W.; Begzsuren, K.; Behnke, O.; Behrendt, O.; Belousov, A.; Bizot, J.C.; Boudry, V.; Bozovic-Jelisavcic, I.; Bracinik, J.; Brandt, G.; Brinkmann, M.; Brisson, V.; Bruncko, D.; Bunyatyan, A.; Buschhorn, G.; Bystritskaya, L.; Campbell, A.J.; Cantun Avila, K.B.; Cassol-Brunner, F.; Cerny, K.; Cerny, V.; Chekelian, V.; Cholewa, A.; Contreras, J.G.; Coughlan, J.A.; Cozzika, G.; Cvach, J.; Dainton, J.B.; Daum, K.; Deak, M.; de Boer, Y.; Delcourt, B.; Del Degan, M.; Delvax, J.; De Roeck, A.; De Wolf, E.A.; Diaconu, C.; Dodonov, V.; Dossanov, A.; Dubak, A.; Eckerlin, G.; Eckstein, D.; Efremenko, V.; Egli, S.; Eliseev, A.; Elsen, E.; Falkiewicz, A.; Faulkner, P.J.W.; Favart, L.; Fedotov, A.; Felst, R.; Feltesse, J.; Ferencei, J.; Fischer, D.J.; Fleischer, M.; Fomenko, A.; Gabathuler, E.; Gayler, J.; Ghazaryan, S.; Glazov, A.; Glushkov, I.; Goerlich, L.; Gogitidze, N.; Gouzevitch, M.; Grab, C.; Greenshaw, T.; Grell, B.R.; Grindhammer, G.; Habib, S.; Haidt, D.; Hansson, M.; Helebrant, C.; Henderson, R.C.W.; Hennekemper, E.; Henschel, H.; Herbst, M.; Herrera, G.; Hildebrandt, M.; Hiller, K.H.; Hoffmann, D.; Horisberger, R.; Hreus, T.; Jacquet, M.; Janssen, M.E.; Janssen, X.; Jemanov, V.; Jonsson, L.; Jung, A.W.; Jung, H.; Kapichine, M.; Katzy, J.; Kenyon, I.R.; Kiesling, C.; Klein, M.; Kleinwort, C.; Kluge, T.; Knutsson, A.; Kogler, R.; Korbel, V.; Kostka, P.; Kraemer, M.; Krastev, K.; Kretzschmar, J.; Kropivnitskaya, A.; Kruger, K.; Kutak, K.; Landon, M.P.J.; Lange, W.; Lastovicka-Medin, G.; Laycock, P.; Lastovicka, T.; Lebedev, A.; Leibenguth, G.; Lendermann, V.; Levonian, S.; Li, G.; Lipka, K.; Liptaj, A.; List, B.; List, J.; Lobodzinska, E.; Loktionova, N.; Lopez-Fernandez, R.; Lubimov, V.; Lytkin, L.; Makankine, A.; Malinovski, E.; Marage, P.; Marti, Ll.; Martyn, H.U.; Maxfield, S.J.; Mehta, A.; Meier, K.; Meyer, A.B.; Meyer, H.; Meyer, H.; Meyer, J.; Michels, V.; Mikocki, S.; Milcewicz-Mika, I.; Moreau, F.; Morozov, A.; Morris, J.V.; Mozer, M.U.; Mudrinic, M.; Muller, K.; Murin, P.; Naroska, B.; Naumann, Th.; Newman, P.R.; Niebuhr, C.; Nikiforov, A.; Nowak, G.; Nowak, K.; Nozicka, M.; Olivier, B.; Olsson, J.E.; Osman, S.; Ozerov, D.; Palichik, V.; Panagoulias, I.; Pandurovic, M.; Papadopoulou, Th.; Pascaud, C.; Patel, G.D.; Pejchal, O.; Perez, E.; Petrukhin, A.; Picuric, I.; Piec, S.; Pitzl, D.; Placakyte, R.; Polifka, R.; Povh, B.; Preda, T.; Radescu, V.; Rahmat, A.J.; Raicevic, N.; Raspiareza, A.; Ravdandorj, T.; Reimer, P.; Rizvi, E.; Robmann, P.; Roland, B.; Roosen, R.; Rostovtsev, A.; Rotaru, M.; Ruiz Tabasco, J.E.; Rurikova, Z.; Rusakov, S.; Salek, D.; Sankey, D.P.C.; Sauter, M.; Sauvan, E.; Schmitt, S.; Schmitz, C.; Schoeffel, L.; Schoning, A.; Schultz-Coulon, H.C.; Sefkow, F.; Shaw-West, R.N.; Sheviakov, I.; Shtarkov, L.N.; Shushkevich, S.; Sloan, T.; Smiljanic, I.; Soloviev, Y.; Sopicki, P.; South, D.; Spaskov, V.; Specka, A.; Staykova, Z.; Steder, M.; Stella, B.; Stoicea, G.; Straumann, U.; Sunar, D.; Sykora, T.; Tchoulakov, V.; Thompson, G.; Thompson, P.D.; Toll, T.; Tomasz, F.; Tran, T.H.; Traynor, D.; Trinh, T.N.; Truol, P.; Tsakov, I.; Tseepeldorj, B.; Turnau, J.; Urban, K.; Valkarova, A.; Vallee, C.; Van Mechelen, P.; Vargas Trevino, A.; Vazdik, Y.; Vinokurova, S.; Volchinski, V.; von den Driesch, M.; Wegener, D.; Wissing, Ch.; Wunsch, E.; Zacek, J.; Zalesak, J.; Zhang, Z.; Zhokin, A.; Zimmermann, T.; Zohrabyan, H.; Zomer, F.

    2009-01-01

    A measurement of the inclusive ep scattering cross section is presented in the region of low momentum transfers, 0.2 GeV^2 < Q^2 < 12 GeV^2, and low Bjorken x, 5x10^-6 < x < 0.02. The result is based on two data sets collected in dedicated runs by the H1 Collaboration at HERA at beam energies of 27.6 GeV and 920 GeV for positrons and protons, respectively. A combination with data previously published by H1 leads to a cross section measurement of a few percent accuracy. A kinematic reconstruction method exploiting radiative ep events extends the measurement to lower Q^2 and larger x. The data are compared with theoretical models which apply to the transition region from photoproduction to deep inelastic scattering.

  10. HELICOBACTER PYLORI AND t(11;18(q21;q21 TRANSLOCATION IN GASTRIC MALT LYMPHOMA

    Directory of Open Access Journals (Sweden)

    Karine Sampaio LIMA

    2014-04-01

    Full Text Available Context Gastric mucosa-associated lymphoid tissue (MALT lymphoma is clearly associated with Helicobacter pylori gastritis and can be cured with anti- H pylori therapy alone. The presence of t(11;18(q21;q21 translocation is thought to predict a lower response rate to anti- H pylori treatment. Objectives To study the presence of t(11;18(q21;q21 genetic translocation and its clinical impact in low-grade gastric MALT lymphoma Brazilian patients. Methods A consecutive series of eight patients with gastric MALT lymphoma were submitted to gastroscopy, endoscopic ultrasound, histopathological examination, H pylori search and RT-PCR-based methodology. All patients received anti-H pylori treatment. Eradicated patients were followed-up every 3-6 months for 2 years. Results Eight patients were studied. All patients had tumor involvement restricted to the mucosa or submucosa and seven patients had low-grade gastric MALT lymphoma. All infected patients achieved H pylori eradication. Histological tumor regression was observed in 5/7 (71% of the low-grade gastric MALT lymphoma patients. The presence of t(11;18(q21;q21 translocation was found in 4 (57% of these patients; among them only two had histological tumor regression following H pylori eradication. Conclusions RT-PCR is a feasible and efficient method to detect t(11;18(q21;q21 translocation, being carried out in routine molecular biology laboratories. The early detection of such translocation can be very helpful for better targeting the therapy to be applied to gastric MALT lymphoma patients.

  11. Measuring health literacy among low literate people: an exploratory feasibility study with the HLS-EU questionnaire.

    Science.gov (United States)

    Storms, Hannelore; Claes, Neree; Aertgeerts, Bert; Van den Broucke, Stephan

    2017-05-19

    Health literacy (HL) is defined as necessary competencies to make well-informed decisions. As patients' decision making is a key element of patient-centered health care, insight in patients' HL might help healthcare professionals to organize their care accordingly. This is particularly true for people in a vulnerable situation, potentially with limited HL, who are, for instance, at greater risk of having limited access to care [1, 2]. As HL correlates with education, instruments should allow inclusion of low literate people. To that end, the relatively new instrument, HLS-EU-Q47, was subjected to a comprehensibility test, its shorter version, HLS-EU-Q16, was not. Therefore, the goal of this study was to examine feasibility of HLS-EU-Q16 (in Dutch) for use in a population of people with low literacy. Purposive sampling of adults with low (yearly) income (literacy. However, to facilitate the use and interpretation, some questions would benefit from minor adjustments: by simplifying wording or providing explanatory, contextual information.

  12. Understanding High Rate Behavior Through Low Rate Analog

    Science.gov (United States)

    2014-04-28

    challenges in high rate character- isation of polymers. The most important is that, owing to their low stress wavespeed, the structural response of...box’ tool, to provide supporting date for the rate dependent mechanical character- isation . Experiments were performed on a TA instruments Q800

  13. Planck 2015 results: II. Low Frequency Instrument data processings

    DEFF Research Database (Denmark)

    Ade, P. A R; Aghanim, N.; Ashdown, M.

    2016-01-01

    We present an updated description of the Planck Low Frequency Instrument (LFI) data processing pipeline, associated with the 2015 data release. We point out the places where our results and methods have remained unchanged since the 2013 paper and we highlight the changes made for the 2015 release...

  14. Measurement of the inclusive ep scattering cross section at low Q2 and x at HERA

    International Nuclear Information System (INIS)

    Aaron, F.D.; Alexa, C.; Preda, T.; Rotaru, M.; Stoicea, G.; Andreev, V.; Belousov, A.; Eliseev, A.; Fomenko, A.; Gogitidze, N.; Lebedev, A.; Loktionova, N.; Malinovski, E.; Rusakov, S.; Sheviakov, I.; Shtarkov, L.N.; Soloviev, Y.; Vazdik, Y.; Antunovic, B.; Aplin, S.; Bartel, W.; Brandt, G.; Brinkmann, M.; Campbell, A.J.; Cholewa, A.; Deak, M.; Boer, Y. de; Roeck, A. de; Eckerlin, G.; Elsen, E.; Felst, R.; Fischer, D.J.; Fleischer, M.; Gayler, J.; Glazov, A.; Grell, B.R.; Haidt, D.; Helebrant, C.; Janssen, M.E.; Jung, H.; Katzy, J.; Kleinwort, C.; Knutsson, A.; Korbel, V.; Kraemer, M.; Krastev, K.; Kutak, K.; Levonian, S.; List, J.; Marti, L.; Meyer, A.B.; Meyer, H.; Meyer, J.; Michels, V.; Niebuhr, C.; Nikiforov, A.; Nozicka, M.; Olsson, J.E.; Panagoulias, I.; Papadopoulou, T.; Pitzl, D.; Placakyte, R.; Radescu, V.; Rurikova, Z.; Schmitt, S.; Sefkow, F.; Staykova, Z.; Steder, M.; Toll, T.; Vargas Trevino, A.; Vinokurova, S.; Driesch, M. von den; Wissing, C.; Wuensch, E.; Asmone, A.; Stella, B.; Astvatsatourov, A.; Delvax, J.; Wolf, E.A. de; Favart, L.; Hreus, T.; Janssen, X.; Marage, P.; Mozer, M.U.; Roland, B.; Roosen, R.; Sunar, D.; Sykora, T.; Mechelen, P. van; Backovic, S.; Dubak, A.; Lastovicka-Medin, G.; Picuric, I.; Raicevic, N.; Baghdasaryan, A.; Ghazaryan, S.; Volchinski, V.; Zohrabyan, H.; Barrelet, E.; Begzsuren, K.; Ravdandorj, T.; Tseepeldorj, B.; Behnke, O.; Behrendt, O.; South, D.; Wegener, D.; Bizot, J.C.; Brisson, V.; Delcourt, B.; Jacquet, M.; Li, G.; Pascaud, C.; Tran, T.H.; Zhang, Z.; Zomer, F.; Boudry, V.; Gouzevitch, M.; Moreau, F.; Specka, A.; Bozovic-Jelisavcic, I.; Mudrinic, M.; Pandurovic, M.; Smiljanic, I.; Bracinik, J.; Faulkner, P.J.W.; Kenyon, I.R.; Newman, P.R.; Shaw-West, R.N.; Thompson, P.D.; Bruncko, D.; Cerny, V.; Ferencei, J.; Murin, P.; Tomasz, F.; Bunyatyan, A.; Buschhorn, G.; Chekelian, V.; Dossanov, A.; Grindhammer, G.; Kiesling, C.; Kogler, R.; Liptaj, A.; Olivier, B.; Raspiareza, A.; Shushkevich, S.; Bystritskaya, L.; Efremenko, V.; Fedotov, A.; Kropivnitskaya, A.; Lubimov, V.; Ozerov, D.; Petrukhin, A.; Rostovtsev, A.; Zhokin, A.; Cantun Avila, K.B.; Contreras, J.G.; Ruiz Tabasco, J.E.; Cassol-Brunner, F.; Diaconu, C.; Hoffmann, D.; Sauvan, E.; Trinh, T.N.; Vallee, C.; Cerny, K.; Pejchal, O.; Polifka, R.; Salek, D.; Valkarova, A.; Zacek, J.; Coughlan, J.A.; Morris, J.V.; Sankey, D.P.C.; Cozzika, G.; Feltesse, J.; Perez, E.; Schoeffel, L.; Cvach, J.; Reimer, P.; Zalesak, J.; Dainton, J.B.; Gabathuler, E.; Greenshaw, T.; Klein, M.; Kluge, T.; Kretzschmar, J.; Laycock, P.; Maxfield, S.J.; Mehta, A.; Patel, G.D.; Rahmat, A.J.; Daum, K.; Meyer, H.; Del Degan, M.; Grab, C.; Leibenguth, G.; Sauter, M.; Zimmermann, T.; Dodonov, V.; Lytkin, L.; Povh, B.; Eckstein, D.; Glushkov, I.; Henschel, H.; Hiller, K.H.; Kostka, P.; Lange, W.; Lastovicka, T.; Lobodzinska, E.; Naumann, T.; Piec, S.; Egli, S.; Hildebrandt, M.; Horisberger, R.; Falkiewicz, A.; Goerlich, L.; Mikocki, S.; Milcewicz-Mika, I.; Nowak, G.; Sopicki, P.; Turnau, J.; Habib, S.; Jemanov, V.; Lipka, K.; List, B.; Naroska, B.; Hansson, M.; Joensson, L.; Osman, S.; Henderson, R.C.W.; Sloan, T.; Hennekemper, E.; Herbst, M.; Jung, A.W.; Krueger, K.; Lendermann, V.; Meier, K.; Schultz-Coulon, H.C.; Urban, K.; Herrera, G.; Lopez-Fernandez, R.; Kapichine, M.; Makankine, A.; Morozov, A.; Palichik, V.; Spaskov, V.; Tchoulakov, V.; Landon, M.P.J.; Rizvi, E.; Thompson, G.; Traynor, D.; Martyn, H.U.; Mueller, K.; Nowak, K.; Robmann, P.; Schmitz, C.; Straumann, U.; Truoel, P.; Schoening, A.; Tsakov, I.

    2009-01-01

    A measurement of the inclusive ep scattering cross section is presented in the region of low momentum transfers, 0.2 GeV 2 ≤Q 2 ≤12 GeV 2 , and low Bjorken x, 5.10 -6 ≤x≤0.02. The result is based on two data sets collected in dedicated runs by the H1 Collaboration at HERA at beam energies of 27.6 GeV and 920 GeV for positrons and protons, respectively. A combination with data previously published by H1 leads to a cross section measurement of a few percent accuracy. A kinematic reconstruction method exploiting radiative ep events extends the measurement to lower Q 2 and larger x. The data are compared with theoretical models which apply to the transition region from photoproduction to deep inelastic scattering. (orig.)

  15. Open-Source Low-Cost Wireless Potentiometric Instrument for pH Determination Experiments

    Science.gov (United States)

    Jin, Hao; Qin, Yiheng; Pan, Si; Alam, Arif U.; Dong, Shurong; Ghosh, Raja; Deen, M. Jamal

    2018-01-01

    pH determination is an essential experiment in many chemistry laboratories. It requires a potentiometric instrument with extremely low input bias current to accurately measure the voltage between a pH sensing electrode and a reference electrode. In this technology report, we propose an open-source potentiometric instrument for pH determination…

  16. The QUIET Instrument

    Energy Technology Data Exchange (ETDEWEB)

    Bischoff, C.; et al.

    2012-07-01

    The Q/U Imaging ExperimenT (QUIET) is designed to measure polarization in the Cosmic Microwave Background, targeting the imprint of inflationary gravitational waves at large angular scales ({approx}1{sup o}). Between 2008 October and 2010 December, two independent receiver arrays were deployed sequentially on a 1.4m side-fed Dragonian telescope. The polarimeters which form the focal planes use a highly compact design based on High Electron Mobility Transistors (HEMTs) that provides simultaneous measurements of the Stokes parameters Q, U, and I in a single module. The 17-element Q-band polarimeter array, with a central frequency of 43.1 GHz, has the best sensitivity (69 {mu}Ks{sup 1/2}) and the lowest instrumental systematic errors ever achieved in this band, contributing to the tensor-to-scalar ratio at r < 0:1. The 84-element W-band polarimeter array has a sensitivity of 87 {mu}Ks{sup 1/2} at a central frequency of 94.5 GHz. It has the lowest systematic errors to date, contributing at r < 0:01. The two arrays together cover multipoles in the range {ell} {approx} 25 -- 975. These are the largest HEMT-based arrays deployed to date. This article describes the design, calibration, performance of, and sources of systematic error for the instrument.

  17. Measurement of D{sup *{+-}} production at low Q{sup 2} with the beam-pipe calorimeter of ZEUS at HERA

    Energy Technology Data Exchange (ETDEWEB)

    Irrgang, P

    2004-12-01

    The production of D* mesons in deep-inelastic ep-scattering has been studied using the ZEUS detector at HERA. The total D* production cross-section and the differential cross-sections as functions of Q{sup 2}, y, p{sub t}(D*) and {eta}(D*) have been measured at low Q{sup 2}. The data sample used was collected during the period 1998-2000 and amounts to an integrated luminosity of 82.2 pb{sup -1}. The low Q{sup 2} region could be reached using the beam-pipe calorimeter which measures the scattered electron at very small angles. Therefore special emphasis was put on the calibration of the BPC in order to reconstruct events in the kinematic range 0.05 < Q{sup 2} < 0.7 GeV{sup 2} and 0.02 < y < 0.85. The D* mesons have been identified via the decay into lighter mesons D{sup *}+{yields}K{sup -}{pi}{sup +}{pi}{sup -} and the charged conjugated decay in the kinematic region 1.5Q{sup 2} in agreement with the corresponding perturbative QCD predictions. (orig.)

  18. Beam helicity asymmetries in K{sup +}Λ electroproduction off the proton at low Q{sup 2}

    Energy Technology Data Exchange (ETDEWEB)

    Achenbach, P.; Ayerbe Gayoso, C.; Boehm, R.; Distler, M.O.; Esser, A.; Gomez Rodriguez, M.; Merkel, H.; Mueller, U.; Pochodzalla, J.; Sanchez Majos, S.; Schlimme, B.S.; Schoth, M.; Schulz, F.; Sfienti, C.; Thiel, M. [Johannes Gutenberg-Universitaet, Institut fuer Kernphysik, Mainz (Germany); Borodina, O. [Johannes Gutenberg-Universitaet, Institut fuer Kernphysik, Mainz (Germany); GSI Helmholtz Centre for Heavy Ion Research, Darmstadt (Germany); Bosnar, D.; Friscic, I. [University of Zagreb, Department of Physics, Faculty of Science, Zagreb (Croatia); Bozkurt, V.; Kim, E.; Rappold, C. [GSI Helmholtz Centre for Heavy Ion Research, Darmstadt (Germany); Bydzovsky, P.; Skoupil, D. [Nuclear Physics Institute, Rez (Czech Republic); Debenjak, L.; Sirca, S. [University of Ljubljana and Institut ' ' Jozef Stefan' ' , Ljubljana (Slovenia); Fujii, Y.; Gogami, T.; Hashimoto, O.; Hirose, S.; Kanda, H.; Kaneta, M.; Nagao, S.; Nakamura, S.N.; Tsukada, K. [Tohoku University, Department of Physics, Sendai (Japan); Margaryan, A. [Yerevan Physics Institute, Yerevan (Armenia); Reinhold, J. [Florida International University, Department of Physics, Miami, FL (United States); Saito, T.R. [Johannes Gutenberg-Universitaet, Institut fuer Kernphysik, Mainz (Germany); GSI Helmholtz Centre for Heavy Ion Research, Darmstadt (Germany); Helmholtz Institute Mainz, Mainz (Germany); Sanchez Lorente, A. [Helmholtz Institute Mainz, Mainz (Germany); Tang, L. [Hampton University, Department of Physics, Hampton, VA (United States); Collaboration: A1 Collaboration

    2017-10-15

    Beam helicity asymmetries in the vector ep → e{sup '}K{sup +}Λ reaction have been measured at unprecedentedly low four-momentum transfers left angle Q{sup 2} right angle = 0.05 (GeV/c){sup 2}. At the Mainz Microtron (MAMI), the experiment was performed with a longitudinally polarized beam and an out-of-plane detection of the scattered electron. This experiment probed the associated helicity-dependent structure function dσ{sub LT}{sup {sub '}}/dΩ{sub K}{sup c.m.}, which is sensitive to the details of resonances of the proton. The results were compared to models for kaon electroproduction using effective Lagrangians. The MAMI data is not supporting the Kaon-Maid isobar model, which uses strong longitudinal couplings of the virtual photon to nucleon resonances and predicts a strong peaking of the structure function at forward angles and low Q{sup 2}. The data is also in disagreement with a Regge-plus-resonance model that predicts the incorrect sign of the structure function. The combination of the MAMI results with data taken at higher four-momentum transfers measured at Jefferson Lab indicates a smooth transition in Q{sup 2} without significant changes of the interference pattern in the electroproduction process. (orig.)

  19. Instrumentation and Fluorescent Chemistries Used in qPCR

    DEFF Research Database (Denmark)

    Josefsen, Mathilde Hartmann; Löfström, Charlotta; Hansen, Trine

    2012-01-01

    will be discussed from a user perspective leading to an instrument selection guide. Differences between fluorescent DNA binding dyes and target-specific fluorescently labeled primers or probes for detection of amplicon accumulation will be discussed, along with the properties and applications of the most frequently...

  20. Low Cost SU8 Based Above IC Process for High Q RF Power Inductors Integration

    International Nuclear Information System (INIS)

    Ghannam, A.; Bourrier, D.; Viallon, Ch.; Parra, Th.

    2011-01-01

    This paper presents a new process for integration of high-Q RF power inductors above low resistivity silicon substrates. The process uses the SU8 resin as a dielectric layer. The aim of using the SU8 is to form thick dielectric layer that can enhance the performance of the inductors. The flexibility of the process enables the possibility to realize complex shaped planar inductors with various dielectric and metal thicknesses to meet the requirements of the application. Q values of 55 at 5 GHz has been demonstrated for an inductance value of 0.8 nH using a 60 μm thick SU8 layer and 30 μm thick copper ribbons. (author)

  1. Assessment of Patient-Reported Outcome Instruments to Assess Chronic Low Back Pain.

    Science.gov (United States)

    Ramasamy, Abhilasha; Martin, Mona L; Blum, Steven I; Liedgens, Hiltrud; Argoff, Charles; Freynhagen, Rainer; Wallace, Mark; McCarrier, Kelly P; Bushnell, Donald M; Hatley, Noël V; Patrick, Donald L

    2017-06-01

     To identify patient-reported outcome (PRO) instruments that assess chronic low back pain (cLBP) symptoms (specifically pain qualities) and/or impacts for potential use in cLBP clinical trials to demonstrate treatment benefit and support labeling claims.  Literature review of existing PRO measures.  Publications detailing existing PRO measures for cLBP were identified, reviewed, and summarized. As recommended by the US Food & Drug Administration (FDA) PRO development guidance, standard measurement characteristics were reviewed, including development history, psychometric properties (validity and reliability), ability to detect change, and interpretation of observed changes.  Thirteen instruments were selected and reviewed: Low Back Pain Bothersomeness Scale, Neuropathic Pain Symptom Inventory, PainDETECT, Pain Quality Assessment Scale Revised, Revised Short Form McGill Pain Questionnaire, Low Back Pain Impact Questionnaire, Oswestry Disability Index, Pain Disability Index, Roland-Morris Disability Questionnaire, Brief Pain Inventory and Brief Pain Inventory Short Form, Musculoskeletal Outcomes Data Evaluation and Management System Spine Module, Orebro Musculoskeletal Pain Questionnaire, and the West Haven-Yale Multidimensional Pain Inventory Interference Scale. The instruments varied in the aspects of pain and/or impacts that they assessed, and none of the instruments fulfilled all criteria for use in clinical trials to support labeling claims based on recommendations outlined in the FDA PRO guidance.  There is an unmet need for a validated PRO instrument to evaluate cLBP-related symptoms and impacts for use in clinical trials. © 2017 American Academy of Pain Medicine. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com

  2. High Precision Measurement of the Proton Elastic Form Factor Ratio at Low Q2

    Energy Technology Data Exchange (ETDEWEB)

    Xiaohui Zhan

    2009-12-01

    A high precision measurement of the proton elastic form factor ratio µpGEp/GMp in the range Q2 = 0.3–0.7 GeV2/c2 was performed using recoil polarimetry in Jefferson Lab Hall A. In this low Q2 range, previous data from LEDEX [5] along with many fits and calculations [2, 3, 4] indicate substantial deviations of the ratio from unity. In this new measurement, with 80% polarized electron beam for 24 days, we are able to achieve <1% statistical uncertainty. Preliminary results are a few percent lower than expected from previous world data and fits, indicating a smaller GEp at this region. Beyond the intrinsic interest in nucleon structure, the improved form factor measurements also have implications for DVCS, determinations of the proton Zemach radius and strangeness form factors through parity violation experiments.

  3. Jet Production in ep Collisions at Low Q^2 and Determination of $\\alpha_{s}$

    CERN Document Server

    Aaron, F.D.; Alexa, C.; Andreev, V.; Antunovic, B.; Backovic, S.; Baghdasaryan, A.; Barrelet, E.; Bartel, W.; Begzsuren, K.; Belousov, A.; Bizot, J.C.; Boudry, V.; Bozovic-Jelisavcic, I.; Bracinik, J.; Brandt, G.; Brinkmann, M.; Brisson, V.; Bruncko, D.; Bunyatyan, A.; Buschhorn, G.; Bystritskaya, L.; Campbell, A.J.; Cantun Avila, K.B.; Cerny, K.; Cerny, V.; Chekelian, V.; Cholewa, A.; Contreras, J.G.; Coughlan, J.A.; Cozzika, G.; Cvach, J.; Dainton, J.B.; Daum, K.; Deak, M.; Delcourt, B.; Delvax, J.; De Wolf, E.A.; Diaconu, C.; Dodonov, V.; Dossanov, A.; Dubak, A.; Eckerlin, G.; Efremenko, V.; Egli, S.; Eliseev, A.; Elsen, E.; Falkiewicz, A.; Favart, L.; Fedotov, A.; Felst, R.; Feltesse, J.; Ferencei, J.; Fischer, D.J.; Fleischer, M.; Fomenko, A.; Gabathuler, E.; Gayler, J.; Ghazaryan, Samvel; Glazov, A.; Glushkov, I.; Goerlich, L.; Gogitidze, N.; Gouzevitch, M.; Grab, C.; Greenshaw, T.; Grell, B.R.; Grindhammer, G.; Habib, S.; Haidt, D.; Helebrant, C.; Henderson, R.C.W.; Hennekemper, E.; Henschel, H.; Herbst, M.; Herrera, G.; Hildebrandt, M.; Hiller, K.H.; Hoffmann, D.; Horisberger, R.; Hreus, T.; Jacquet, M.; Janssen, X.; Jonsson, L.; Jung, A.W.; Jung, H.; Kapichine, M.; Katzy, J.; Kenyon, I.R.; Kiesling, C.; Klein, M.; Kleinwort, C.; Kluge, T.; Knutsson, A.; Kogler, R.; Kosior, E.; Kostka, P.; Kraemer, M.; Krastev, K.; Kretzschmar, J.; Kropivnitskaya, A.; Kruger, K.; Kutak, K.; Landon, M.P.J.; Lange, W.; Lastovicka-Medin, G.; Laycock, P.; Lebedev, A.; Lendermann, V.; Levonian, S.; Li, G.; Lipka, K.; Liptaj, A.; List, B.; List, J.; Loktionova, N.; Lopez-Fernandez, R.; Lubimov, V.; Makankine, A.; Malinovski, E.; Marage, P.; Marti, Ll.; Martyn, H.U.; Maxfield, S.J.; Mehta, A.; Meyer, A.B.; Meyer, H.; Meyer, H.; Meyer, J.; Mikocki, S.; Milcewicz-Mika, I.; Moreau, F.; Morozov, A.; Morris, J.V.; Mozer, M.U.; Mudrinic, M.; Muller, K.; Murin, P.; Naumann, Th.; Newman, P.R.; Niebuhr, C.; Nikiforov, A.; Nikitin, D.; Nowak, G.; Nowak, K.; Olsson, J.E.; Osman, S.; Ozerov, D.; Palichik, V.; Panagoulias, I.; Pandurovic, M.; Papadopoulou, Th.; Pascaud, C.; Patel, G.D.; Pejchal, O.; Perez, E.; Petrukhin, A.; Picuric, I.; Piec, S.; Pitzl, D.; Placakyte, R.; Pokorny, B.; Polifka, R.; Povh, B.; Radescu, V.; Rahmat, A.J.; Raicevic, N.; Raspiareza, A.; Ravdandorj, T.; Reimer, P.; Rizvi, E.; Robmann, P.; Roland, B.; Roosen, R.; Rostovtsev, A.; Rotaru, M.; Tabasco, J.E.Ruiz; Rusakov, S.; Salek, D.; Sankey, D.P.C.; Sauter, M.; Sauvan, E.; Schmitt, S.; Schoeffel, L.; Schoning, A.; Schultz-Coulon, H.C.; Sefkow, F.; Shaw-West, R.N.; Shtarkov, L.N.; Shushkevich, S.; Sloan, T.; Smiljanic, Ivan; Soloviev, Y.; Sopicki, P.; South, D.; Spaskov, V.; Specka, A.; Staykova, Z.; Steder, M.; Stella, B.; Stoicea, G.; Straumann, U.; Sunar, D.; Sykora, T.; Tchoulakov, V.; Thompson, G.; Thompson, P.D.; Toll, T.; Tomasz, F.; Tran, T.H.; Traynor, D.; Trinh, T.N.; Truol, P.; Tsakov, I.; Tseepeldorj, B.; Turnau, J.; Urban, K.; Valkarova, A.; Vallee, C.; Van Mechelen, P.; Trevino, A.Vargas; Vazdik, Y.; Vinokurova, S.; Volchinski, V.; von den Driesch, M.; Wegener, D.; Wissing, Ch.; Wunsch, E.; Zacek, J.; Zalesak, J.; Zhang, Z.; Zhokin, A.; Zimmermann, T.; Zohrabyan, H.; Zomer, F.

    2010-01-01

    The production of jets is studied in deep-inelastic e+p scattering at low negative four momentum transfer squared 5<Q^2<100 GeV^2 and at inelasticity 0.2Q^2 and jet transverse momentum. The 2-jet cross section is also measured as a function of the proton momentum fraction xi. The measurements are well described by perturbative quantum chromodynamics at next-to-leading order corrected for hadronisation effects and are subsequently used to extract the strong coupling alpha_s.

  4. Measurement of the inclusive ep scattering cross section at low Q{sup 2} and x at HERA

    Energy Technology Data Exchange (ETDEWEB)

    Aaron, F.D. [National Inst. for Physics and Nuclear Engineering (NIPNE), Bucharest (Romania); Bucharest Univ. (Romania). Faculty of Physics; Alexa, C. [National Inst. for Physics and Nuclear Engineering (NIPNE), Bucharest (Romania); Andreev, V. [Lebedev (P.N.) Physical Inst., Moscow (RU)] (and others)

    2009-02-15

    A measurement of the inclusive ep scattering cross section is presented in the region of low momentum transfers, 0.2 GeV{sup 2}{<=}Q{sup 2}{<=}12 GeV{sup 2}, and low Bjorken x, 5.10{sup -6}Q{sup 2} and larger x. The data are compared with theoretical models which apply to the transition region from photoproduction to deep inelastic scattering. (orig.)

  5. Low-cost coding of directivity information for the recording of musical instruments

    Science.gov (United States)

    Braasch, Jonas; Martens, William L.; Woszczyk, Wieslaw

    2004-05-01

    Most musical instruments radiate sound according to characteristic spatial directivity patterns. These patterns are usually not only strongly frequency dependent, but also time-variant functions of various parameters of the instrument, such as pitch and the playing technique applied (e.g., plucking versus bowing of string instruments). To capture the directivity information when recording an instrument, Warusfel and Misdariis (2001) proposed to record an instrument using four channels, one for the monopole and the others for three orthogonal dipole parts. In the new recording setup presented here, it is proposed to store one channel at a high sampling frequency, along with directivity information that is updated only every few milliseconds. Taking the binaural sluggishness of the human auditory system into account in this way provides a low-cost coding scheme for subsequent reproduction of time-variant directivity patterns.

  6. Design and analysis of high gain and low noise figure CMOS low noise amplifier for Q-band nano-sensor application

    Science.gov (United States)

    Suganthi, K.; Malarvizhi, S.

    2018-03-01

    A high gain, low power, low Noise figure (NF) and wide band of milli-meter Wave (mmW) circuits design at 50 GHz are used for Radio Frequency (RF) front end. The fundamental necessity of a receiver front-end includes perfect output and input impedance matching and port-to-port isolation with high gain and low noise over the entire band of interest. In this paper, a design of Cascade-Cascode CMOS LNA circuit at 50 GHz for Q-band application is proposed. The design of Low noise amplifier at 50 GHz using Agilent ADS tool with microstrip lines which provides simplicity in fabrication and less chip area. The low off-leakage current Ioff can be maintained with high K-dielectrics CMOS structure. Nano-scale electronics can be achieved with increased robustness. The design has overall gain of 11.091 dB and noise figure of 2.673 dB for the Q-band of 48.3 GHz to 51.3 GHz. Impedance matching is done by T matching network and the obtained input and output reflection coefficients are S11 = <-10 dB and S22 = <-10 dB. Compared to Silicon (Si) material, Wide Band Gap semiconductor materials used attains higher junction temperatures which is well matched to ceramics used in packaging technology, the protection and reliability also can be achieved with the electronic packaging. The reverse transmission coefficient S21 is less than -21 dB has shown that LNA has better isolation between input and output, Stability factor greater than 1 and Power is also optimized in this design. Layout is designed, power gain of 4.6 dB is achieved and area is optimized which is nearly equal to 502 740 μm2. The observed results show that the proposed Cascade-Cascode LNA design can find its suitability in future milli-meter Wave Radar application.

  7. Measurement of the proton structure function F2 at low χand low Q2 at HERA

    International Nuclear Information System (INIS)

    Derrick, M.; Krakauer, D.; Magill, S.

    1995-10-01

    We report on a measurement of the proton structure function F 2 in the range 3.5x10 -5 ≤x≤4x10 -3 and 1.5 GeV 2 ≤Q 2 ≤15 GeV 2 at the ep collider HERA operating at a centre-of-mass energy of √s=300 GeV. The rise of F 2 with decreasing x observed in the previous HERA measurements persists in this lower x and Q 2 range. The Q 2 evolution of F 2 , even at the lowest Q 2 and x measured, is consistent with perturbative QCD. (orig.)

  8. Possible Heavy Tetraquarks qQ(-q-Q), qq(-Q-Q) and qQ(-Q-Q)%可能的qQ(-q-Q),qq(-Q-Q)和qQ(-Q-Q)重四夸克态

    Institute of Scientific and Technical Information of China (English)

    崔莹; 陈晓林; 邓卫真; 朱世琳

    2007-01-01

    Assuming X(3872) is a qc-q-c tetraquark and using its mass as input, we perform a schematic study of the masses of possible heavy tetraquarks using the color-magnetic interaction with the flavor symmetry breaking corrections.%假设X(3872)是一个qc(-q-c)四夸克态,并用它的质量作为输入,用具有味对称性破坏的色磁相互作用系统研究了可能的重四夸克态的质量谱.

  9. Low power data acquisition unit for autonomous geophysical instrumentation

    Science.gov (United States)

    Prystai, Andrii

    2017-04-01

    The development of an autonomous instrumentation for field research is always a challenge which needs knowledge and application of recent advances in technology and components production. Using this information a super-low power, low-cost, stand-alone GPS time synchronized data acquisition unit was created. It comprises an extended utilization of the microcontroller modules and peripherals and special firmware with flexible PLL parameters. The present report is devoted to a discussion of synchronization mode of data sampling in autonomous field instruments with possibility of GPS random breaks. In the result the achieved sampling timing accuracy is better than ± 60 ns without phase jumps and distortion plus fixed shift depending on the sample rate. The main application of the system is for simultaneous measurement of several channels from magnetic and electric sensors in field conditions for magneto-telluric instruments. First utilization of this system was in the new developed versions of LEMI-026 magnetometer and LEMI-423 field station, where it was applied for digitizing of up to 6 analogue channels with 32-bit resolution in the range ± 2.5V, digital filtration (LPF) and maximum sample rate 4kS/s. It is ready for record in 5 minutes after being turned on. Recently, this system was successfully utilized with the drone-portable magnetometers destined for the search of metallic objects, like UXO, in rural areas, research of engineering underground structure and for mapping ore bodies. The successful tests of drone-portable system were made and tests results are also discussed.

  10. Res-Parity: Parity Violation in Inelastic scattering at Low Q2

    International Nuclear Information System (INIS)

    Paul Reimer; Peter Bosted; John Arrington; Hamlet Mkrtchyan; Xiaochao Zheng

    2006-01-01

    Parity violating electron scattering has become a well established tool which has been used, for example, to probe the Standard Model and the strange-quark contribution to the nucleon. While much of this work has focused on elastic scattering, the RES-Parity experiment, which has been proposed to take place at Jefferson Laboratory, would focus on inelastic scattering in the low-Q 2 , low-W domain. RES-Parity would search for evidence of quark-hadron duality and resonance structure with parity violation in the resonance region. In terms of parity violation, this region is essentially unexplored, but the interpretation of other high-precision electron scattering experiments will rely on a reasonable understanding of scattering at lower energy and low-W through the effects of radiative corrections. RES-Parity would also study nuclear effects with the weak current. Because of the intrinsic broad band energy spectrum of neutrino beams, neutrino experiments are necessarily dependent on an untested, implicit assumption that these effects are identical to electromagnetic nuclear effects. RES-Parity is a relatively straight forward experiment. With a large expected asymmetry (∼ 0.5 x 10 -4 ) these studies may be completed with in a relatively brief period

  11. Role of low order rational q-values in the ITB events in JT-60U reverse shear plasmas

    International Nuclear Information System (INIS)

    Neudatchin, S.V.; Takizuka, T.; Hayashi, N.; Isayama, A.; Shirai, H.; Fujita, T.; Kamada, Y.; Koide, Y.; Suzuki, T.

    2004-01-01

    Non-local confinement bifurcations inside and around internal transport barriers (ITBs) with a ms timescale (ITB events) have previously been found in JT-60U reverse shear (RS) and high-β p plasmas. ITB events are observed as the simultaneous rise and decay of T e in two zones. They are created by an abrupt non-local reduction (or increase) of heat flux inside 30-40% of the minor radius. Under sufficient neutral beam power P nbi (above ∼8 MW for the 1.2-1.5 MA/3.8 T pulses described below), ITB events were previously detected at various q min values. However, the role of q min equal to 3.5, 3, 2.5, 2 is not obvious for ITB formation. In this paper, we focus on new features of ITB evolution near low-order-rational values of q min . The formation of a stronger ITB and its further splitting into two radially separated ITBs is described. These ITBs are located in both positive and negative shear zones of a plasma with L-mode edge. The similarity of space-time evolution of T e and T i at sufficient power is highlighted (even when the variation is significant and complicated in space and time). Within error-bars, ITB splitting occurs as q min passes through 2.5. The similarity of space-time evolution of T e and T i suggests a similarity in the qualitative behaviour of electron and ion heat diffusivities in time and space. The temporal formation of an ITB in the zone with small positive shear, while q min passes through 3 (after periodical improvements and degradations via ITB events with 8 ms period) in H-mode, with P nbi = 8 MW, is described. At lower powers, ITB events are observed only near rational values of q min . In weak RS shots with P nbi = 4 MW, transport is reduced via ITB events during 0.08 s at q min = 3.5, and repetitive short-term phases of reduced transport are observed as q min passes through 3. The behaviour of T i looks different. The difference in T e and T i evolution, which was detected regularly under low power, probably indicates a decoupling

  12. Combination of classical test theory (CTT) and item response theory (IRT) analysis to study the psychometric properties of the French version of the Quality of Life Enjoyment and Satisfaction Questionnaire-Short Form (Q-LES-Q-SF).

    Science.gov (United States)

    Bourion-Bédès, Stéphanie; Schwan, Raymund; Epstein, Jonathan; Laprevote, Vincent; Bédès, Alex; Bonnet, Jean-Louis; Baumann, Cédric

    2015-02-01

    The study aimed to examine the construct validity and reliability of the Quality of Life Enjoyment and Satisfaction Questionnaire-Short Form (Q-LES-Q-SF) according to both classical test and item response theories. The psychometric properties of the French version of this instrument were investigated in a cross-sectional, multicenter study. A total of 124 outpatients with a substance dependence diagnosis participated in the study. Psychometric evaluation included descriptive analysis, internal consistency, test-retest reliability, and validity. The dimensionality of the instrument was explored using a combination of the classical test, confirmatory factor analysis (CFA), and an item response theory analysis, the Person Separation Index (PSI), in a complementary manner. The results of the Q-LES-Q-SF revealed that the questionnaire was easy to administer and the acceptability was good. The internal consistency and the test-retest reliability were 0.9 and 0.88, respectively. All items were significantly correlated with the total score and the SF-12 used in the study. The CFA with one factor model was good, and for the unidimensional construct, the PSI was found to be 0.902. The French version of the Q-LES-Q-SF yielded valid and reliable clinical assessments of the quality of life for future research and clinical practice involving French substance abusers. In response to recent questioning regarding the unidimensionality or bidimensionality of the instrument and according to the underlying theoretical unidimensional construct used for its development, this study suggests the Q-LES-Q-SF as a one-dimension questionnaire in French QoL studies.

  13. Flight experience with lightweight, low-power miniaturized instrumentation systems

    Science.gov (United States)

    Hamory, Philip J.; Murray, James E.

    1992-01-01

    Engineers at the NASA Dryden Flight Research Facility (NASA-Dryden) have conducted two flight research programs with lightweight, low-power miniaturized instrumentation systems built around commercial data loggers. One program quantified the performance of a radio-controlled model airplane. The other program was a laminar boundary-layer transition experiment on a manned sailplane. The purpose of this paper is to report NASA-Dryden personnel's flight experience with the miniaturized instrumentation systems used on these two programs. The paper will describe the data loggers, the sensors, and the hardware and software developed to complete the systems. The paper also describes how the systems were used and covers the challenges encountered to make them work. Examples of raw data and derived results will be shown as well. Finally, future plans for these systems will be discussed.

  14. Elastic J/ψ production at low Q2 at HERA

    International Nuclear Information System (INIS)

    Huber, Florian

    2010-05-01

    In this diploma thesis the elastic J/ψ vector meson photoproduction (ep→eJ/ψp) is studied in the decay channel J/ψ→e + e - with the H1 detector at the electron proton collider HERA. The data from the runs of the year 2007 with an integrated luminosity of 62.4 pb -1 are used. In this time HERA operated with tree different proton energies E p called high (920 GeV), medium (575 GeV) and low (460 GeV) with integrated luminosities 45.5 (high), 5.96 (medium) and 10.9 pb -1 (low). The kinematical region of vertical stroke t vertical stroke 2 , where t is the four momentum transfer at the proton vertex, and Q e 2 γp , is restricted to 40 GeV γp γp γp -b 0 vertical stroke t vertical stroke , which yields to b 0 =4.4±0.2(stat.). The cross section as a function of W γp is fitted by a power law, dσ/dW γp ∝W δ γp , and gives δ=0.66±0.07(stat.). (orig.)

  15. Measurement of the Proton Structure Function $F_{2}$ at low $Q^{2}$ in QED Compton Scattering at HERA

    CERN Document Server

    Aktas, A.; Anthonis, T.; Asmone, A.; Babaev, A.; Backovic, S.; Bahr, J.; Baranov, P.; Barrelet, E.; Bartel, W.; Baumgartner, S.; Becker, J.; Beckingham, M.; Behnke, O.; Behrendt, O.; Belousov, A.; Berger, Ch.; Berger, N.; Berndt, T.; Bizot, J.C.; Bohme, J.; Boenig, M.-O.; Boudry, V.; Bracinik, J.; Brisson, V.; Broker, H.-B.; Brown, D.P.; Bruncko, D.; Busser, F.W.; Bunyatyan, A.; Buschhorn, G.; Bystritskaya, L.; Campbell, A.J.; Caron, S.; Cassol-Brunner, F.; Cerny, K.; Chekelian, V.; Collard, C.; Contreras, J.G.; Coppens, Y.R.; Coughlan, J.A.; Cox, B.E.; Cozzika, G.; Cvach, J.; Dainton, J.B.; Dau, W.D.; Daum, K.; Delcourt, B.; Demirchyan, R.; De Roeck, A.; Desch, K.; De Wolf, E.A.; Diaconu, C.; Dingfelder, J.; Dodonov, V.; Dubak, A.; Duprel, C.; Eckerlin, Guenter; Efremenko, V.; Egli, S.; Eichler, R.; Eisele, F.; Ellerbrock, M.; Elsen, E.; Erdmann, M.; Erdmann, W.; Faulkner, P.J.W.; Favart, L.; Fedotov, A.; Felst, R.; Ferencei, J.; Fleischer, M.; Fleischmann, P.; Fleming, Y.H.; Flucke, G.; Flugge, G.; Fomenko, A.; Foresti, I.; Formanek, J.; Franke, G.; Frising, G.; Gabathuler, E.; Gabathuler, K.; Garutti, E.; Garvey, J.; Gayler, J.; Gerhards, R.; Gerlich, C.; Ghazaryan, Samvel; Goerlich, L.; Gogitidze, N.; Gorbounov, S.; Grab, C.; Grassler, H.; Greenshaw, T.; Gregori, M.; Grindhammer, Guenter; Gwilliam, C.; Haidt, D.; Hajduk, L.; Haller, J.; Hansson, M.; Heinzelmann, G.; Henderson, R.C.W.; Henschel, H.; Henshaw, O.; Heremans, R.; Herrera, G.; Herynek, I.; Heuer, R.-D.; Hildebrandt, M.; Hiller, K.H.; Hoting, P.; Hoffmann, D.; Horisberger, R.; Hovhannisyan, A.; Ibbotson, M.; Ismail, M.; Jacquet, M.; Janauschek, L.; Janssen, X.; Jemanov, V.; Jonsson, L.; Johnson, D.P.; Jung, H.; Kant, D.; Kapichine, M.; Karlsson, M.; Katzy, J.; Keller, N.; Kennedy, J.; Kenyon, I.R.; Kiesling, Christian M.; Klein, M.; Kleinwort, C.; Klimkovich, T.; Kluge, T.; Knies, G.; Knutsson, A.; Koblitz, B.; Korbel, V.; Kostka, P.; Koutouev, R.; Kropivnitskaya, A.; Kroseberg, J.; Kuckens, J.; Kuhr, T.; Landon, M.P.J.; Lange, W.; Lastovicka, T.; Laycock, P.; Lebedev, A.; Leiner, B.; Lemrani, R.; Lendermann, V.; Levonian, S.; Lindfeld, L.; Lipka, K.; List, B.; Lobodzinska, E.; Loktionova, N.; Lopez-Fernandez, R.; Lubimov, V.; Lueders, H.; Luke, D.; Lux, T.; Lytkin, L.; Makankine, A.; Malden, N.; Malinovski, E.; Mangano, S.; Marage, P.; Marks, J.; Marshall, R.; Martisikova, M.; Martyn, H.-U.; Maxfield, S.J.; Meer, D.; Mehta, A.; Meier, K.; Meyer, A.B.; Meyer, H.; Meyer, J.; Michine, S.; Mikocki, S.; Milcewicz-Mika, I.; Milstead, D.; Mohamed, A.; Moreau, F.; Morozov, A.; Morozov, I.; Morris, J.V.; Mozer, Matthias Ulrich; Muller, K.; Murin, P.; Nagovizin, V.; Naroska, B.; Naumann, J.; Naumann, Th.; Newman, Paul R.; Niebuhr, C.; Nikiforov, A.; Nikitin, D.; Nowak, G.; Nozicka, M.; Oganezov, R.; Olivier, B.; Olsson, J.E.; Ossoskov, G.; Ozerov, D.; Pascaud, C.; Patel, G.D.; Peez, M.; Perez, E.; Perieanu, A.; Petrukhin, A.; Pitzl, D.; Placakyte, R.; Poschl, R.; Portheault, B.; Povh, B.; Raicevic, N.; Ratiani, Z.; Reimer, P.; Reisert, B.; Rimmer, A.; Risler, C.; Rizvi, E.; Robmann, P.; Roland, B.; Roosen, R.; Rostovtsev, A.; Rurikova, Z.; Rusakov, S.; Rybicki, K.; Sankey, D.P.C.; Sauvan, E.; Schatzel, S.; Scheins, J.; Schilling, F.-P.; Schleper, P.; Schmidt, S.; Schmitt, S.; Schneider, M.; Schoeffel, L.; Schoning, A.; Schroder, V.; Schultz-Coulon, H.-C.; Schwanenberger, C.; Sedlak, K.; Sefkow, F.; Sheviakov, I.; Shtarkov, L.N.; Sirois, Y.; Sloan, T.; Smirnov, P.; Soloviev, Y.; South, D.; Spaskov, V.; Specka, Arnd E.; Spitzer, H.; Stamen, R.; Stella, B.; Stiewe, J.; Strauch, I.; Straumann, U.; Tchoulakov, V.; Thompson, Graham; Thompson, P.D.; Tomasz, F.; Traynor, D.; Truoel, Peter; Tsipolitis, G.; Tsurin, I.; Turnau, J.; Tzamariudaki, E.; Uraev, A.; Urban, Marcel; Usik, A.; Utkin, D.; Valkar, S.; Valkarova, A.; Vallee, C.; Van Mechelen, P.; Van Remortel, N.; Vargas Trevino, A.; Vazdik, Y.; Veelken, C.; Vest, A.; Vinokurova, S.; Volchinski, V.; Wacker, K.; Wagner, J.; Weber, G.; Weber, R.; Wegener, D.; Werner, C.; Werner, N.; Wessels, M.; Wessling, B.; Winter, G.-G.; Wissing, Ch.; Woehrling, E.-E.; Wolf, R.; Wunsch, E.; Xella, S.; Yan, W.; Yeganov, V.; Zacek, J.; Zalesak, J.; Zhang, Z.; Zhokin, A.; Zohrabyan, H.; Zomer, F.

    2004-01-01

    The proton structure function F_2(x,Q^2) is measured in inelastic QED Compton scattering using data collected with the H1 detector at HERA. QED Compton events are used to access the kinematic range of very low virtualities of the exchanged photon, Q^2, down to 0.5 GeV^2, and Bjorken x up to \\sim 0.06, a region which has not been covered previously by inclusive measurements at HERA. The results are in agreement with the measurements from fixed target lepton-nucleon scattering experiments.

  16. Q resolution calculation of small angle neutron scattering spectrometer and analysis of form factor

    International Nuclear Information System (INIS)

    Chen Liang; Peng Mei; Wang Yan; Sun Liangwei; Chen Bo

    2011-01-01

    The calculational methods of Small Angle Neutron Scattering (SANS) spectrometer Q resolution function and its correlative Q standard difference were introduced. The effects of Q standard difference were analysed with the geometry lay out of spectrometer and the spread of neutron wavelength. The one dimension Q resolution Gaussian function were analysed. The form factor curve of ideal solid sphere and two different instrument arrangement parameter was convoluted respectively and the different smearing curve of form factor was obtained. The combination of using the Q resolution function to more accurately analysis SANS data. (authors)

  17. Core outcome measurement instruments for clinical trials in nonspecific low back pain

    Science.gov (United States)

    Chiarotto, Alessandro; Boers, Maarten; Deyo, Richard A.; Buchbinder, Rachelle; Corbin, Terry P.; Costa, Leonardo O.P.; Foster, Nadine E.; Grotle, Margreth; Koes, Bart W.; Kovacs, Francisco M.; Lin, C.-W. Christine; Maher, Chris G.; Pearson, Adam M.; Peul, Wilco C.; Schoene, Mark L.; Turk, Dennis C.; van Tulder, Maurits W.; Terwee, Caroline B.; Ostelo, Raymond W.

    2018-01-01

    Abstract To standardize outcome reporting in clinical trials of patients with nonspecific low back pain, an international multidisciplinary panel recommended physical functioning, pain intensity, and health-related quality of life (HRQoL) as core outcome domains. Given the lack of a consensus on measurement instruments for these 3 domains in patients with low back pain, this study aimed to generate such consensus. The measurement properties of 17 patient-reported outcome measures for physical functioning, 3 for pain intensity, and 5 for HRQoL were appraised in 3 systematic reviews following the COSMIN methodology. Researchers, clinicians, and patients (n = 207) were invited in a 2-round Delphi survey to generate consensus (≥67% agreement among participants) on which instruments to endorse. Response rates were 44% and 41%, respectively. In round 1, consensus was achieved on the Oswestry Disability Index version 2.1a for physical functioning (78% agreement) and the Numeric Rating Scale (NRS) for pain intensity (75% agreement). No consensus was achieved on any HRQoL instrument, although the Short Form 12 (SF12) approached the consensus threshold (64% agreement). In round 2, a consensus was reached on an NRS version with a 1-week recall period (96% agreement). Various participants requested 1 free-to-use instrument per domain. Considering all issues together, recommendations on core instruments were formulated: Oswestry Disability Index version 2.1a or 24-item Roland-Morris Disability Questionnaire for physical functioning, NRS for pain intensity, and SF12 or 10-item PROMIS Global Health form for HRQoL. Further studies need to fill the evidence gaps on the measurement properties of these and other instruments. PMID:29194127

  18. Precise determination of low-Q nucleon electromagnetic form factors and their impact on parity-violating e-p elastic scattering

    International Nuclear Information System (INIS)

    Arrington, John; Sick, Ingo

    2007-01-01

    The extraction of the strangeness form factors from parity-violating elastic electron-proton scattering is sensitive to the electromagnetic form factors at low Q 2 . We provide parametrizations for the form factors and uncertainties, including the effects of two-photon exchange corrections to the extracted electromagnetic form factors. We study effect of the correlations between different form factors, in particular as they impact the parity-violating asymmetry and the extraction of the strangeness form factors. We provide a prescription to extract the strangeness form factors from the asymmetry that provides an excellent approximation of the full two-photon correction. The corrected form factors are also appropriate as input for other low-Q analyses, although the effects of correlations and two-photon exchange corrections may be different

  19. The Coach-Athlete Relationship Questionnaire (CART-Q): development and initial validation.

    Science.gov (United States)

    Jowett, Sophia; Ntoumanis, Nikos

    2004-08-01

    The purpose of the present study was to develop and validate a self-report instrument that measures the nature of the coach-athlete relationship. Jowett et al.'s (Jowett & Meek, 2000; Jowett, in press) qualitative case studies and relevant literature were used to generate items for an instrument that measures affective, cognitive, and behavioral aspects of the coach-athlete relationship. Two studies were carried out in an attempt to assess content, predictive, and construct validity, as well as internal consistency, of the Coach-Athlete Relationship Questionnaire (CART-Q), using two independent British samples. Principal component analysis and confirmatory factor analysis were used to reduce the number of items, identify principal components, and confirm the latent structure of the CART-Q. Results supported the multidimensional nature of the coach-athlete relationship. The latent structure of the CART-Q was underlined by the latent variables of coaches' and athletes' Closeness (emotions), Commitment (cognitions), and Complementarity (behaviors).

  20. Two-photon collisions at very low Q2 from LEP2. Forthcoming results

    International Nuclear Information System (INIS)

    Almehed, S.; Jarlskog, G.; Mjornmark, U.; Nygren, A.; Zimin, N.; Kapusta, F.; Tyapkin, I.

    1998-01-01

    Experimental results that may soon be obtained in two-photon collisions at very low momentum transfer Q 2 at LEP2 are reviewed. A kinematical range is presented for both the forward and very forward detectors used to measure scattered electrons and positrons. A new acceptance, after this year's upgrade of the beam pipe at the position of the very forward detectors, is evaluated. The corresponding statistics is calculated for an integrated luminosity of 400 pb -1 , that must be collected by the end of LEP2 operation according to current plans

  1. Novel features of 3q29 deletion syndrome: Results from the 3q29 registry

    Science.gov (United States)

    Glassford, Megan R.; Rosenfeld, Jill A.; Freedman, Alexa A.; Zwick, Michael E.

    2016-01-01

    3q29 deletion syndrome is caused by a recurrent, typically de novo heterozygous 1.6 Mb deletion, but because incidence of the deletion is rare (1 in 30,000 births) the phenotype is not well described. To characterize the range of phenotypic manifestations associated with 3q29 deletion syndrome, we have developed an online registry (3q29deletion.org) for ascertainment of study subjects and phenotypic data collection via Internet‐based survey instruments. We report here on data collected during the first 18 months of registry operation, from 44 patients. This is the largest cohort of 3q29 deletion carriers ever assembled and surveyed in a systematic way. Our data reveal that 28% of registry participants report neuropsychiatric phenotypes, including anxiety disorder, panic attacks, depression, bipolar disorder, and schizophrenia. Other novel findings include a high prevalence (64%) of feeding problems in infancy and reduced weight at birth for 3q29 deletion carriers (average reduction 13.9 oz (394 g), adjusted for gestational age and sex, P = 6.5e‐07). We further report on the frequency of heart defects, autism, recurrent ear infections, gastrointestinal phenotypes, and dental phenotypes, among others. We also report on the expected timing of delayed developmental milestones. This is the most comprehensive description of the 3q29 deletion phenotype to date. These results are clinically actionable toward improving patient care for 3q29 deletion carriers, and can guide the expectations of physicians and parents. These data also demonstrate the value of patient‐reported outcomes to reveal the full phenotypic spectrum of rare genomic disorders. © 2016 The Authors. American Journal of Medical Genetics Part A Published by Wiley Periodicals, Inc. PMID:26738761

  2. Absorption band Q model for the earth

    International Nuclear Information System (INIS)

    Anderson, D.L.; Given, J.W.

    1982-01-01

    Body wave, surface wave, and normal mode data are used to place constraints on the frequency dependence of Q in the mantle. With a simple absorption band model it is possible to satisfy the shear sensitive data over a broad frequency range. The quality factor Q/sub s/(ω) is proportional to ω/sup α/ in the band and to ω and ω -1 at higher and lower frequencies, respectively, as appropriate for a relaxation mechanism with a spectrum of relaxation time. The parameters of the band are Q(min) = 80, α = 0.15, and width, 5 decades. The center of the band varies from 10 1 seconds in the upper mantle, to 1.6 x 10 3 seconds in the lower mantle. The shift of the band with depth is consistent with the expected effects of temperature, pressure and stress. High Q, regions of the mantle are attributed to a shift of the absorption band to longer periods. To satisfy the gravest fundamental spheroidal modes and the ScS data, the absorption band must shift back into the short-period seismic band at the base of the mantle. This may be due to a high temperature gradient or high shear stresses. A preliminary attempt is also made to specify bulk dissipation in the mantle and core. Specific features of the absorption band model are low Q in the body wave band at both the top and the base of the mantle, low Q for long-period body waves in the outer core, an inner core Q 2 that increases with period, and low Q/sub p//Q/sub s/ at short periods in the middle mantel. The short-period Q/sub s/ increases rapidly at 400 km and is relatively constant from this depth to 2400 km. The deformational Q of the earth at a period of 14 months is predicted to be 463

  3. Active filter for INDUS-2 Q4 and Q5 power supplies

    International Nuclear Information System (INIS)

    Singh, Y.P.; Thakurta, A.C.; Kotaiah, S.

    2003-01-01

    Q4 and Q5 power supplies are SCR based power supplies wherein the rectified voltage is fed to a passive filter to reduce the ripple voltage. The output of the passive filter still contains some ripple particularly on the low frequency side. Attenuation of this ripple with passive filter necessitates increase in size of L and C and leads to sluggishness of the system. The design and the test results of an active filter module have been discussed wherein the low frequency attenuation can be very effectively taken care of by, allowing this to be absorbed in a coupling transformer put after the passive filter. Considerable size reduction has been achieved by using switching techniques. Low frequency attenuation has been made quite a simple task. This filter also helps in handling transients from input. (author)

  4. Measurement of the proton structure function F(x,Q) at low x

    Science.gov (United States)

    H1 Collaboration; Aaron, F. D.; Alexa, C.; Andreev, V.; Antunovic, B.; Aplin, S.; Asmone, A.; Astvatsatourov, A.; Bacchetta, A.; Backovic, S.; Baghdasaryan, A.; Baranov, P.; Barrelet, E.; Bartel, W.; Beckingham, M.; Begzsuren, K.; Behnke, O.; Belousov, A.; Berger, N.; Bizot, J. C.; Boenig, M.-O.; Boudry, V.; Bozovic-Jelisavcic, I.; Bracinik, J.; Brandt, G.; Brinkmann, M.; Brisson, V.; Bruncko, D.; Bunyatyan, A.; Buschhorn, G.; Bystritskaya, L.; Campbell, A. J.; Cantun Avila, K. B.; Cassol-Brunner, F.; Cerny, K.; Cerny, V.; Chekelian, V.; Cholewa, A.; Contreras, J. G.; Coughlan, J. A.; Cozzika, G.; Cvach, J.; Dainton, J. B.; Daum, K.; Deák, M.; de Boer, Y.; Delcourt, B.; Del Degan, M.; Delvax, J.; de Roeck, A.; de Wolf, E. A.; Diaconu, C.; Dodonov, V.; Dossanov, A.; Dubak, A.; Eckerlin, G.; Efremenko, V.; Egli, S.; Eliseev, A.; Elsen, E.; Essenov, S.; Falkiewicz, A.; Faulkner, P. J. W.; Favart, L.; Fedotov, A.; Felst, R.; Feltesse, J.; Ferencei, J.; Finke, L.; Fleischer, M.; Fomenko, A.; Gabathuler, E.; Gayler, J.; Ghazaryan, S.; Glazov, A.; Glushkov, I.; Goerlich, L.; Goettlich, M.; Gogitidze, N.; Gouzevitch, M.; Grab, C.; Greenshaw, T.; Grell, B. R.; Grindhammer, G.; Habib, S.; Haidt, D.; Hansson, M.; Helebrant, C.; Henderson, R. C. W.; Henschel, H.; Herrera, G.; Hildebrandt, M.; Hiller, K. H.; Hoffmann, D.; Horisberger, R.; Hovhannisyan, A.; Hreus, T.; Jacquet, M.; Janssen, M. E.; Janssen, X.; Jemanov, V.; Jönsson, L.; Johnson, D. P.; Jung, A. W.; Jung, H.; Kapichine, M.; Katzy, J.; Kenyon, I. R.; Kiesling, C.; Klein, M.; Kleinwort, C.; Klimkovich, T.; Kluge, T.; Knutsson, A.; Kogler, R.; Korbel, V.; Kostka, P.; Kraemer, M.; Krastev, K.; Kretzschmar, J.; Kropivnitskaya, A.; Krüger, K.; Kutak, K.; Landon, M. P. J.; Lange, W.; Laštovička-Medin, G.; Laycock, P.; Lebedev, A.; Leibenguth, G.; Lendermann, V.; Levonian, S.; Li, G.; Lipka, K.; Liptaj, A.; List, B.; List, J.; Loktionova, N.; Lopez-Fernandez, R.; Lubimov, V.; Lucaci-Timoce, A.-I.; Lytkin, L.; Makankine, A.; Malinovski, E.; Marage, P.; Marti, Ll.; Martyn, H.-U.; Maxfield, S. J.; Mehta, A.; Meier, K.; Meyer, A. B.; Meyer, H.; Meyer, H.; Meyer, J.; Michels, V.; Mikocki, S.; Milcewicz-Mika, I.; Moreau, F.; Morozov, A.; Morris, J. V.; Mozer, M. U.; Mudrinic, M.; Müller, K.; Murín, P.; Nankov, K.; Naroska, B.; Naumann, Th.; Newman, P. R.; Niebuhr, C.; Nikiforov, A.; Nowak, G.; Nowak, K.; Nozicka, M.; Olivier, B.; Olsson, J. E.; Osman, S.; Ozerov, D.; Palichik, V.; Panagoulias, I.; Pandurovic, M.; Papadopoulou, Th.; Pascaud, C.; Patel, G. D.; Pejchal, O.; Peng, H.; Perez, E.; Petrukhin, A.; Picuric, I.; Piec, S.; Pitzl, D.; Plačakytė, R.; Polifka, R.; Povh, B.; Preda, T.; Radescu, V.; Rahmat, A. J.; Raicevic, N.; Raspiareza, A.; Ravdandorj, T.; Reimer, P.; Rizvi, E.; Robmann, P.; Roland, B.; Roosen, R.; Rostovtsev, A.; Rotaru, M.; Ruiz Tabasco, J. E.; Rurikova, Z.; Rusakov, S.; Salek, D.; Salvaire, F.; Sankey, D. P. C.; Sauter, M.; Sauvan, E.; Schmidt, S.; Schmitt, S.; Schmitz, C.; Schoeffel, L.; Schöning, A.; Schultz-Coulon, H.-C.; Sefkow, F.; Shaw-West, R. N.; Sheviakov, I.; Shtarkov, L. N.; Shushkevich, S.; Sloan, T.; Smiljanic, I.; Smirnov, P.; Soloviev, Y.; Sopicki, P.; South, D.; Spaskov, V.; Specka, A.; Staykova, Z.; Steder, M.; Stella, B.; Straumann, U.; Sunar, D.; Sykora, T.; Tchoulakov, V.; Thompson, G.; Thompson, P. D.; Toll, T.; Tomasz, F.; Tran, T. H.; Traynor, D.; Trinh, T. N.; Truöl, P.; Tsakov, I.; Tseepeldorj, B.; Tsurin, I.; Turnau, J.; Tzamariudaki, E.; Urban, K.; Valkárová, A.; Vallée, C.; van Mechelen, P.; Vargas Trevino, A.; Vazdik, Y.; Vinokurova, S.; Volchinski, V.; Wegener, D.; Wessels, M.; Wissing, Ch.; Wünsch, E.; Yeganov, V.; Žáček, J.; Zálešák, J.; Zhang, Z.; Zhelezov, A.; Zhokin, A.; Zhu, Y. C.; Zimmermann, T.; Zohrabyan, H.; Zomer, F.

    2008-07-01

    A first measurement is reported of the longitudinal proton structure function F(x,Q) at the ep collider HERA. It is based on inclusive deep inelastic ep scattering cross section measurements with a positron beam energy of 27.5 GeV and proton beam energies of 920, 575 and 460 GeV. Employing the energy dependence of the cross section, F is measured in a range of squared four-momentum transfers 12⩽Q⩽90 GeV and low Bjorken x0.00024⩽x⩽0.0036. The F values agree with higher order QCD calculations based on parton densities obtained using cross section data previously measured at HERA.

  5. Measuring health literacy among low literate people: an exploratory feasibility study with the HLS-EU questionnaire

    Directory of Open Access Journals (Sweden)

    Hannelore Storms

    2017-05-01

    Full Text Available Abstract Background Health literacy (HL is defined as necessary competencies to make well-informed decisions. As patients’ decision making is a key element of patient-centered health care, insight in patients’ HL might help healthcare professionals to organize their care accordingly. This is particularly true for people in a vulnerable situation, potentially with limited HL, who are, for instance, at greater risk of having limited access to care [1, 2]. As HL correlates with education, instruments should allow inclusion of low literate people. To that end, the relatively new instrument, HLS-EU-Q47, was subjected to a comprehensibility test, its shorter version, HLS-EU-Q16, was not. Therefore, the goal of this study was to examine feasibility of HLS-EU-Q16 (in Dutch for use in a population of people with low literacy. Methods Purposive sampling of adults with low (yearly income (< €16,965.47 and limited education (maximum high school, with Dutch language proficiency. Exclusion criteria were: psychiatric, neurodegenerative diseases or impairments. To determine suitability (length, comprehension and layout participants were randomly distributed either HLS-EU-Q16 or a modified version and were interviewed directly afterwards by one researcher. To determine feasibility a qualitative approach was chosen: cognitive interviews were carried out using the verbal probing technique. Results Thirteen participants completed HLS-EU-Q16 (n = 7 or the modified version (n = 6. Questions about ‘disease prevention’ or ‘appraisal’ of information are frequently reported to be incomprehensible. Difficulties are attributed to vocabulary, sentence structure and the decision process (abstraction, distinguishing ‘appraising’ from ‘applying’ information, indecisive on the appropriate response. Conclusions HLS-EU-Q16 is a suitable instrument to determine HL in people with limited literacy. However, to facilitate the use and interpretation, some

  6. Cdh13 and AdipoQ gene knockout alter instrumental and Pavlovian drug conditioning.

    Science.gov (United States)

    King, C P; Militello, L; Hart, A; St Pierre, C L; Leung, E; Versaggi, C L; Roberson, N; Catlin, J; Palmer, A A; Richards, J B; Meyer, P J

    2017-09-01

    Genome-wide association studies in humans have suggested that variants of the cadherin-13 (CDH13) gene are associated with substance use disorder, subjective response to amphetamine, and attention deficit hyperactivity disorder. To examine the role of the Cdh13 and its peptide ligand adiponectin (AdipoQ) in addiction-related behaviors, we assessed Cdh13 knockout (KO) rats and AdipoQ KO mice using intravenous cocaine self-administration and conditioned place preference (CPP) paradigms. During intravenous cocaine self-administration, male Cdh13 heterozygous (+/-) and KO (-/-) rats showed increased cue-induced reinstatement compared with wild-type (WT) rats when presented with a cocaine-paired stimulus, whereas female Cdh13 rats showed no differences across genotype. Cdh13 -/- rats showed higher responding for a saccharin reinforcer and learned the choice reaction time (RT) task more slowly than WTs. However, we found no differences between Cdh13 -/- and +/+ rats in responding for sensory reinforcement, number of premature responses in the RT task, tendency to approach a Pavlovian food cue, CPP and locomotor activation to cocaine (10 or 20 mg/kg). In AdipoQ -/- mice, there was a significant increase in CPP to methamphetamine (1 mg/kg) but not to a range of d-amphetamine doses (0.5, 1, 2 and 4 mg/kg). Taken together, these data suggest that Cdh13 and AdipoQ regulate sensitivity to psychomotor stimulants and palatable rewards without producing major changes in other behaviors. In humans, these two genes may regulate sensitivity to natural and drug rewards, thus influencing susceptibility to the conditioned drug effects and relapse. © 2017 John Wiley & Sons Ltd and International Behavioural and Neural Genetics Society.

  7. Reduction in bacterial counts in infected root canals after rotary or hand nickel-titanium instrumentation--a clinical study.

    Science.gov (United States)

    Rôças, I N; Lima, K C; Siqueira, J F

    2013-07-01

    To compare the antibacterial efficacy of two instrumentation techniques, one using hand nickel-titanium (NiTi) instruments and the other using rotary NiTi instruments, in root canals of teeth with apical periodontitis. Root canals from single-rooted teeth were instrumented using either hand NiTi instruments in the alternated rotation motion technique or rotary BioRaCe instruments. The irrigant used in both groups was 2.5% NaOCl. DNA extracts from samples taken before and after instrumentation were subjected to quantitative analysis by real-time polymerase chain reaction (qPCR). Qualitative analysis was also performed using presence/absence data from culture and qPCR assays. Bacteria were detected in all S1 samples by both methods. In culture analysis, 45% and 35% of the canals were still positive for bacterial presence after hand and rotary NiTi instrumentation, respectively (P > 0.05). Rotary NiTi instrumentation resulted in significantly fewer qPCR-positive cases (60%) than hand NiTi instrumentation (95%) (P = 0.01). Intergroup comparison of quantitative data showed no significant difference between the two techniques. There was no significant difference in bacterial reduction in infected canals after instrumentation using hand or rotary NiTi instruments. In terms of incidence of positive results for bacteria, culture also showed no significant differences between the groups, but the rotary NiTi instrumentation resulted in more negative results in the more sensitive qPCR analysis. © 2013 International Endodontic Journal. Published by John Wiley & Sons Ltd.

  8. Low-sensitivity, low-bounce, high-linearity current-controlled oscillator suitable for single-supply mixed-mode instrumentation system.

    Science.gov (United States)

    Hwang, Yuh-Shyan; Kung, Che-Min; Lin, Ho-Cheng; Chen, Jiann-Jong

    2009-02-01

    A low-sensitivity, low-bounce, high-linearity current-controlled oscillator (CCO) suitable for a single-supply mixed-mode instrumentation system is designed and proposed in this paper. The designed CCO can be operated at low voltage (2 V). The power bounce and ground bounce generated by this CCO is less than 7 mVpp when the power-line parasitic inductance is increased to 100 nH to demonstrate the effect of power bounce and ground bounce. The power supply noise caused by the proposed CCO is less than 0.35% in reference to the 2 V supply voltage. The average conversion ratio KCCO is equal to 123.5 GHz/A. The linearity of conversion ratio is high and its tolerance is within +/-1.2%. The sensitivity of the proposed CCO is nearly independent of the power supply voltage, which is less than a conventional current-starved oscillator. The performance of the proposed CCO has been compared with the current-starved oscillator. It is shown that the proposed CCO is suitable for single-supply mixed-mode instrumentation systems.

  9. Anomalous Q(sub 0) Results in the CEBAF South Linac

    International Nuclear Information System (INIS)

    William J. Schneider; M. Drury; Joe Preble

    1993-01-01

    While in practice, the performance of cavities - Q(sub 0) versus E(sub acc) - in the assembled CEBAF cryomodule corresponds in nearly every respect to the performance as measured in the vertical test area; there are a few cases where this is not true. On six (6) of the twenty (20) cryomodules installed in the south linac, cavity 4 specifically, and one other cavity in cryomodule 7 have an anomalous low Q(sub 0). Investigation into the source of the low Q(sub 0) on these particular cavities have centered around trapped magnetic fields, slow cooldowns or maldistribution of He flow during cooldown leading to hydride precipitation and Q(sub 0) disease. Other possibilities such as low window Q(sub 0)'s or harmonic content of the klystron were also considered. A detailed investigation to understand the phenomena leading to the low Q(sub 0)'s on cryomodule 7 and 8 is discussed. We have found evidence suggesting cooldown dependent Q(sub 0) disease as well as window heating to account for some of the discrepancies but not all. A complete explanation of the problem is still under further investigation

  10. Skew cyclic codes over F_q+uF_q+vF_q+uvF_q

    Directory of Open Access Journals (Sweden)

    Ting Yao

    2015-09-01

    Full Text Available In this paper, we study skew cyclic codes over the ring $R=F_q+uF_q+vF_q+uvF_q$, where $u^{2}=u,v^{2}=v,uv=vu$, $q=p^{m}$ and $p$ is an odd prime. We investigate the structural properties of skew cyclic codes over $R$ through a decomposition theorem. Furthermore, we give a formula for the number of skew cyclic codes of length $n$ over $R.$

  11. Exploration of extremely low q_e_d_g_e regime in KSTAR

    International Nuclear Information System (INIS)

    Kim, Jayhyun; In, Y.; Park, B.H.; Aydemir, A.

    2015-01-01

    The q_e_d_g_e < 2 regime had long been regarded as an experimentally forbidden regime due to magneto-hydrodynamic instabilities. However, RFX-MOD experiment demonstrated that the control of error field could enable the entrance and sustainment of the discharge even in the forbidden regime. We explored q_e_d_g_e < 2 regime in Korea superconducting tokamak advanced research (KSTAR) without any feedback or feedforward control of error field since the intrinsic level of error field in KSTAR is inherently comparable to the controlled level of other device. The discharge sustained at q_9_5 ∼ 1.9 for 800 ms that is at least one order of magnitude longer than the resistive wall time of the device. Furthermore, simulated error field applied by field error correction coils prevented the passage of q_e_d_g_e = 3 integer rational surface before reaching q_e_d_g_e = 2. The detailed analysis is on-going for revealing the role of error field in the excitation of limiting instability. (author)

  12. Low-q structure of Kr gas at undercritical densities. An accurate SANS determination of triplet forces

    International Nuclear Information System (INIS)

    Guarini, E.; Casanova, G.; Genova Univ.; Bafile, U.; Firenze Univ.; Barocchi, F.; Firenze Univ.

    1999-01-01

    Complete text of publication follows. Besides the promising results of very recent attempts to directly measure the triple-dipole interactions in noble fluids, an alternative method can be applied to get much more accurate experimental information on the long-range triplet contributions from the density behavior of the structure factor S(q) in the low-q region. However this method requires the use of a model for the pair potential and its accuracy critically depends on the agreement between the experimental two-body properties of the fluid and the model assumed. It is shown how this condition is remarkably fulfilled by the results of a SANS measurement in gaseous Kr at densities below 4.3 nm -3 , thus leading to and unprecedented accuracy in the evaluation of triple-dipole forces. (author)

  13. Development of microcontroller based instrumentation for low dose implantation

    International Nuclear Information System (INIS)

    Suresh, K.; Saravanan, K.; Panigrahi, B.K.; Nair, K.G.M.

    2011-01-01

    In experiments like ion implantation based ion track formations, the sample is implanted to low doses of the order of 10 10 ions/cm 2 , limiting the ion beam currents to be less than 1-5 x 10 -12 A. However the standard current integrators available are not sensitive to very low currents, causing an unacceptable high level of error in dose measurement. Hence a low dose implantation measurement system has been developed. It consists of a very sensitive low current preamplifier with full scale input 1nA/100pA, a standard current integrator, a microcontroller based interface circuit, which are connected to a personal computer(PC) through USB. Two types of the software are developed for the system: the microcontroller firmware using C and windows based virtual instrument programs using LabVIEW 7.0. Necessary precautions associated with pA level measurement like rigidly fastened good quality cables, low ripple DC power supply, shielding, close mounting of the preamplifier to the sample are adopted. After necessary calibrations with an ECIL make low current source, the system has been put into regular use. Design and development details, salient features are discussed in this paper. (author)

  14. Latest developments of neutron scattering instrumentation at the Juelich Centre for Neutron Science

    International Nuclear Information System (INIS)

    Ioffe, Alexander

    2013-01-01

    Jülich Centre for Neutron Science (JCNS) is operating a number of world-class neutron scattering instruments situated at the most powerful and advanced neutron sources (FRM II, ILL and SNS) and is continuously undertaking significant efforts in the development and upgrades to keep this instrumentation in line with the continuously changing scientific request. These developments are mostly based upon the latest progress in neutron optics and polarized neutron techniques. For example, the low-Q limit of the suite of small angle-scattering instruments has been extended to 4·10 -5 Å -1 by the successful use of focusing optics. A new generation of correction elements for the neutron spin-echo spectrometer has allowed for the use of the full field integral available, thus pushing further the instrument resolution. A significant progress has been achieved in the developments of 3 He neutron spin filters for purposes of the wide-angle polarization analysis for off-specular reflectometry and (grazing incidence) small-angle neutron scattering, e.g. the on-beam polarization of 3 He in large cells is allowing to achieve a high neutron beam polarization without any degradation in time. The wide Q-range polarization analysis using 3 He neutron spin filters has been implemented for small-angle neutron scattering that lead to the reduction up to 100 times of the intrinsic incoherent background from non-deuterated biological molecules. Also the work on wide-angle XYZ magnetic cavities (Magic PASTIS) will be presented. (author)

  15. Planck 2013 results. IV. Low Frequency Instrument beams and window functions

    DEFF Research Database (Denmark)

    Planck Collaboration,; Aghanim, N.; Armitage-Caplan, C.

    2014-01-01

    This paper presents the characterization of the in-flight beams, the beam window functions and the associated errors for the Planck Low Frequency Instrument (LFI). Knowledge of the beam profiles is the key to determining their imprint on the transfer function from the observed to the actual sky a...

  16. Planck 2013 results. IV. Low Frequency Instrument beams and window functions

    DEFF Research Database (Denmark)

    Planck Collaboration,; Aghanim, N.; Armitage-Caplan, C.

    2013-01-01

    This paper presents the characterization of the in-flight beams, the beam window functions and the associated errors for the Planck Low Frequency Instrument (LFI). Knowledge of the beam profiles is the key to determining their imprint on the transfer function from the observed to the actual sky a...

  17. High rates of de novo 15q11q13 inversions in human spermatozoa

    Directory of Open Access Journals (Sweden)

    Molina Òscar

    2012-02-01

    Full Text Available Abstract Low-Copy Repeats predispose the 15q11-q13 region to non-allelic homologous recombination. We have already demonstrated that a significant percentage of Prader-Willi syndrome (PWS fathers have an increased susceptibility to generate 15q11q13 deletions in spermatozoa, suggesting the participation of intrachromatid exchanges. This work has been focused on assessing the incidence of de novo 15q11q13 inversions in spermatozoa of control donors and PWS fathers in order to determine the basal rates of inversions and to confirm the intrachromatid mechanism as the main cause of 15q11q13 anomalies. Semen samples from 10 control donors and 16 PWS fathers were processed and analyzed by triple-color FISH. Three differentially labeled BAC-clones were used: one proximal and two distal of the 15q11-q13 region. Signal associations allowed the discrimination between normal and inverted haplotypes, which were confirmed by laser-scanning confocal microscopy. Two types of inversions were detected which correspond to the segments involved in Class I and II PWS deletions. No significant differences were observed in the mean frequencies of inversions between controls and PWS fathers (3.59% ± 0.46 and 9.51% ± 0.87 vs 3.06% ± 0.33 and 10.07% ± 0.74. Individual comparisons showed significant increases of inversions in four PWS fathers (P Results suggest that the incidence of heterozygous inversion carriers in the general population could reach significant values. This situation could have important implications, as they have been described as predisposing haplotypes for genomic disorders. As a whole, results confirm the high instability of the 15q11-q13 region, which is prone to different types of de novo reorganizations by intrachromatid NAHR.

  18. A Chinese translation of the EdFED-Q and assessment of equivalence.

    Science.gov (United States)

    Lin, Li-Chan; Chang, Chia-Chi

    2003-01-01

    The purpose of this study was to translate the Edinburgh Feeding Evaluation in Dementia Questionnaire (EdFED-Q) from the original English into a Chinese language version and to assess the equivalence of the English and Chinese EdFED-Q versions. To use a directly translated instrument without minimal explanation of the procedures for determining the equivalence between the original and secondary language instrument is questionable. Ensuring equivalence of a translated Chinese version of the EdFED-Q for patients with dementia is an essential prerequisite for identifying culturally specific expressions of feeding difficulty under investigation. Phase 1 consisted of experts doing the initial translation into Chinese and then English back-translations of the questionnaire. Six experts determined the equality of the Chinese and English versions, and five monolingual nurses provided information for the C-EdFED-Q. In phase 2, two bilingual gerontological nurses rated 33 residents with dementia to determine equivalence across time. In phase 3, three groups of bilingual nurses used the Chinese, English, and finally both versions simultaneously to judge a model case's feeding behavior on the videotape. In phase 1, the rating on the equality of the items on the Chinese and English versions was 0.969. In phase 2, kappa coefficients for all items on the C-EdFED-Q and E-EdFED-Q ranged from 0.44 to 1.00. In determining the consistency of the scores for the C-EdFED-Q and E-EdFED-Q between the two raters across time, the intraclass correlation coefficient for the absolute agreement was found to range from 0.85 to 0.90. In phase 3, except for items 6 and 9, all items showed no significant difference among the three groups. Further studies to assess the relationship between constructs and to compare it with known and predicted relationships are recommended.

  19. Dutch Translation and Psychometric Testing of the 9-Item Shared Decision Making Questionnaire (SDM-Q-9) and Shared Decision Making Questionnaire-Physician Version (SDM-Q-Doc) in Primary and Secondary Care.

    Science.gov (United States)

    Rodenburg-Vandenbussche, Sumayah; Pieterse, Arwen H; Kroonenberg, Pieter M; Scholl, Isabelle; van der Weijden, Trudy; Luyten, Gre P M; Kruitwagen, Roy F P M; den Ouden, Henk; Carlier, Ingrid V E; van Vliet, Irene M; Zitman, Frans G; Stiggelbout, Anne M

    2015-01-01

    The SDM-Q-9 and SDM-Q-Doc measure patient and physician perception of the extent of shared decision making (SDM) during a physician-patient consultation. So far, no self-report instrument for SDM was available in Dutch, and validation of the scales in other languages has been limited. The aim of this study was to translate both scales into Dutch and assess their psychometric characteristics. Participants were patients and their treating physicians (general practitioners and medical specialists). Patients (N = 182) rated their consultation using the SDM-Q-9, 43 physicians rated their consultations using the SDM-Q-Doc (N = 201). Acceptability, reliability (internal consistency), and the factorial structure of the instruments were determined. For convergent validity the CPSpost was used. Reliabilities of both scales were high (alpha SDM-Q-9 0.88; SDM-Q-Doc 0.87). The SDM-Q-9 and SDM-Q-Doc total scores correlated as expected with the CPSpost (SDM-Q-9: r = 0.29; SDM-Q-Doc: r = 0.48) and were significantly different between the CPSpost categories, with lowest mean scores when the physician made the decision alone. Principal Component Analyses showed a two-component model for each scale. A confirmatory factor analysis yielded a mediocre, but acceptable, one-factor model, if Item 1 was excluded; for both scales the best indices of fit were obtained for a one-factor solution, if both Items 1 and 9 were excluded. The Dutch SDM-Q-9 and SDM-Q-Doc demonstrate good acceptance and reliability; they correlated as expected with the CPSpost and are suitable for use in Dutch primary and specialised care. Although the best model fit was found when excluding Items 1 and 9, we believe these items address important aspects of SDM. Therefore, also based on the coherence with theory and comparability with other studies, we suggest keeping all nine items of the scale. Further research on the SDM-concept in patients and physicians, in different clinical settings and different countries, is

  20. Analysis of autism susceptibility gene loci on chromosomes 1p, 4p, 6q, 7q, 13q, 15q, 16p, 17q, 19q and 22q in Finnish multiplex families.

    Science.gov (United States)

    Auranen, M; Nieminen, T; Majuri, S; Vanhala, R; Peltonen, L; Järvelä, I

    2000-05-01

    The role of genetic factors in the etiology of the autistic spectrum of disorders has clearly been demonstrated. Ten chromosomal regions, on chromosomes 1p, 4p, 6q, 7q, 13q, 15q, 16p, 17q, 19q and 22q have potentially been linked to autism.1-8 We have analyzed these chromosomal regions in a total of 17 multiplex families with autism originating from the isolated Finnish population by pairwise linkage analysis and sib-pair analysis. Mild evidence for putative contribution was found only with the 1p chromosomal region in the susceptibility to autism. Our data suggest that additional gene loci exist for autism which will be detectable in and even restricted to the isolated Finnish population.

  1. Validity and reliability of a self-administered foot evaluation questionnaire (SAFE-Q).

    Science.gov (United States)

    Niki, Hisateru; Tatsunami, Shinobu; Haraguchi, Naoki; Aoki, Takafumi; Okuda, Ryuzo; Suda, Yasunori; Takao, Masato; Tanaka, Yasuhito

    2013-03-01

    The Japanese Society for Surgery of the Foot (JSSF) is developing a QOL questionnaire instrument for use in pathological conditions related to the foot and ankle. The main body of the outcome instrument (the Self-Administered Foot Evaluation Questionnaire, SAFE-Q version 2) consists of 34 questionnaire items, which provide five subscale scores (1: Pain and Pain-Related; 2: Physical Functioning and Daily Living; 3: Social Functioning; 4: Shoe-Related; and 5: General Health and Well-Being). In addition, the instrument has nine optional questionnaire items that provide a Sports Activity subscale score. The purpose of this study was to evaluate the test-retest reliability of the SAFE-Q. Version 2 of the SAFE-Q was administered to 876 patients and 491 non-patients, and the test-retest reliability was evaluated for 131 patients. In addition, the SF-36 questionnaire and the JSSF Scale scoring form were administered to all of the participants. Subscale scores were scaled such that the final sum of scores ranged between zero (least healthy) to 100 (healthiest). The intraclass correlation coefficients were larger than 0.7 for all of the scores. The means of the five subscale scores were between 60 and 75. The five subscales easily separated patients from non-patients. The coefficients for the correlations of the subscale scores with the scores on the JSSF Scale and the SF-36 subscales were all highly statistically significantly greater than zero (p valid and reliable. In the future, it will be beneficial to test the responsiveness of the SAFE-Q.

  2. eV-TEM: Transmission electron microscopy in a low energy cathode lens instrument

    Energy Technology Data Exchange (ETDEWEB)

    Geelen, Daniël, E-mail: geelen@physics.leidenuniv.nl [Huygens-Kamerlingh Onnes Laboratory, Leiden Institute of Physics, Leiden University, P.O. Box 9504, 2300 RA Leiden (Netherlands); Thete, Aniket [Huygens-Kamerlingh Onnes Laboratory, Leiden Institute of Physics, Leiden University, P.O. Box 9504, 2300 RA Leiden (Netherlands); Schaff, Oliver; Kaiser, Alexander [SPECS GmbH, Voltastrasse 5, D-13355 Berlin (Germany); Molen, Sense Jan van der [Huygens-Kamerlingh Onnes Laboratory, Leiden Institute of Physics, Leiden University, P.O. Box 9504, 2300 RA Leiden (Netherlands); Tromp, Rudolf [IBM T.J. Watson Research Center, 1101 Kitchawan Road, P.O. Box 218, Yorktown Heights, NY 10598 (United States)

    2015-12-15

    We are developing a transmission electron microscope that operates at extremely low electron energies, 0–40 eV. We call this technique eV-TEM. Its feasibility is based on the fact that at very low electron energies the number of energy loss pathways decreases. Hence, the electron inelastic mean free path increases dramatically. eV-TEM will enable us to study elastic and inelastic interactions of electrons with thin samples. With the recent development of aberration correction in cathode lens instruments, a spatial resolution of a few nm appears within range, even for these very low electron energies. Such resolution will be highly relevant to study biological samples such as proteins and cell membranes. The low electron energies minimize adverse effects due to radiation damage. - Highlights: • We present a new way of performing low energy transmission electron microscopy in an aberration corrected LEEM/PEEM instrument. • We show a proof of principle where we measure transmitted electrons through a suspended graphene monolayer with a preliminary setup. • We present an improved setup design that provides better control of the incident electron beam.

  3. Molecular analysis of Hb Q-H disease and Hb Q-Hb E in a Singaporean family.

    Science.gov (United States)

    Tan, J; Tay, J S; Wong, Y C; Kham, S K; Bte Abd Aziz, N; Teo, S H; Wong, H B

    1995-01-01

    Hb Q (alpha 74Asp-His) results from a mutation in the alpha-gene such that abnormal alpha Q-chains are synthesized. The alpha Q-chains combine with the normal Beta A-chains to form abnormal Hb alpha 2Q beta 2A (Hb Q). Hb Q-H disease is rare, and has been reported only in the Chinese. We report here a Chinese family, were the mother diagnosed with Hb Q-H disease and the father with Hb E heterozygosity and a child with Hb Q-E-thalassemia. Thalassemia screening of the mother's blood revealed a Hb level of 6.8g/dl with low MCV and MCH. Her blood film was indicative of thalassemia. Cellulose acetate electrophoresis showed Hb H and Hb Q with the absence of Hb A. Globin chain biosynthesis was carried out and alpha Q- and beta-chains were detected. Normal alpha- chains were absent. Digestion of the mother's DNA with Bam HI and Bgl II followed by hybridization with the 1.5 kb alpha-Pst probe showed a two alpha-gene deletion on one chromosome and the -alpha Q chain mutant with the -alpha 4.2 defect on the other chromosome. DNA amplification studies indicated the two-gene deletion to be of the -SEA/ defect. The patient was concluded to possess Hb Q-H disease (--SEA/-alpha 4.2Q). Cellulose acetate electrophoresis of the father's blood showed the presence of Hb A, F and E. Molecular analysis of the father's DNA confirmed an intact set of alpha-genes (alpha alpha/alpha alpha). Globin chain biosynthesis of fetal blood of their child showed gamma, beta A, beta E, alpha A and alpha Q-chains. Molecular analysis of the child's DNA showed one alpha-gene deletion, thus giving a genotype of alpha alpha/-alpha 4.2Q beta beta E.

  4. Pretreatment with coenzyme Q10 improves ovarian response and embryo quality in low-prognosis young women with decreased ovarian reserve: a randomized controlled trial.

    Science.gov (United States)

    Xu, Yangying; Nisenblat, Victoria; Lu, Cuiling; Li, Rong; Qiao, Jie; Zhen, Xiumei; Wang, Shuyu

    2018-03-27

    Management of women with reduced ovarian reserve or poor ovarian response (POR) to stimulation is one of the major challenges in reproductive medicine. The primary causes of POR remain elusive and oxidative stress was proposed as one of the important contributors. It has been suggested that focus on the specific subpopulations within heterogeneous group of poor responders could assist in evaluating optimal management strategies for these patients. This study investigated the effect of anti-oxidant treatment with coenzyme Q10 (CoQ10) on ovarian response and embryo quality in young low-prognosis patients with POR. This prospective, randomized controlled study included 186 consecutive patients with POR stratified according to the POSEIDON classification group 3 (age reserve parameters). The participants were randomized to the CoQ10 pre-treatment for 60 days preceding IVF-ICSI cycle or no pre-treatment. The number of high quality embryos was a primary outcome measure. A total of 169 participants were evaluated (76 treated with CoQ10 and 93 controls); 17 women were excluded due to low compliance with CoQ10 administration. The baseline demographic and clinical characteristics were comparable between the groups. CoQ10 pretreatment resulted in significantly lower gonadotrophin requirements and higher peak E2 levels. Women in CoQ10 group had increased number of retrieved oocytes (4, IQR 2-5), higher fertilization rate (67.49%) and more high-quality embryos (1, IQR 0-2); p reserve in IVF-ICSI cycles. Further work is required to determine whether there is an effect on clinical treatment endpoints.

  5. Neutron beam instruments at Harwell

    International Nuclear Information System (INIS)

    Baston, A.H.; Harris, D.H.C.

    1978-11-01

    A list and brief descriptions are given of the neutron beam facilities for U.K. scientists at Harwell and in academic institutions, available under an agreement between the Science Research Council and AERE (Harwell). The list falls under the following headings: reactor instruments (single crystal diffractometers, powder diffractometers, triple axis spectrometers, time-of-flight cold neutron twin rotor spectrometer, beryllium filter spectrometer, MARX spectrometer, Harwell small-angle scattering spectrometer); LINAC instruments (total scattering spectrometer, back scattering spectrometer, active sample spectrometer, inelastic rotor spectrometer, constant Q spectrometer); ancillary equipment (cryostats, superconducting magnets, electromagnets, furnaces). (U.K.)

  6. 18q loss of heterozygosity in microsatellite stable colorectal cancer is correlated with CpG island methylator phenotype-negative (CIMP-0) and inversely with CIMP-low and CIMP-high.

    Science.gov (United States)

    Ogino, Shuji; Kawasaki, Takako; Kirkner, Gregory J; Ohnishi, Mutsuko; Fuchs, Charles S

    2007-05-02

    The CpG island methylator phenotype (CIMP) with widespread promoter methylation is a distinct epigenetic phenotype in colorectal cancer, associated with microsatellite instability-high (MSI-high) and BRAF mutations. 18q loss of heterozygosity (LOH) commonly present in colorectal cancer with chromosomal instability (CIN) is associated with global hypomethylation in tumor cell. A recent study has shown an inverse correlation between CIN and CIMP (determined by MINTs, p16, p14 and MLH1 methylation) in colorectal cancer. However, no study has examined 18q LOH in relation to CIMP-high, CIMP-low (less extensive promoter methylation) and CIMP-0 (CIMP-negative), determined by quantitative DNA methylation analysis. Utilizing MethyLight technology (real-time PCR), we quantified DNA methylation in 8 CIMP-specific promoters {CACNA1G, CDKN2A (p16), CRABP1, IGF2, MLH1, NEUROG1, RUNX3 and SOCS1} in 758 non-MSI-high colorectal cancers obtained from two large prospective cohorts. Using four 18q microsatellite markers (D18S55, D18S56, D18S67 and D18S487) and stringent criteria for 18q LOH, we selected 374 tumors (236 LOH-positive tumors with > or = 2 markers showing LOH; and 138 LOH-negative tumors with > or = 3 informative markers and no LOH). CIMP-0 (0/8 methylated promoters) was significantly more common in 18q LOH-positive tumors (59% = 139/236, p = 0.002) than 18q LOH-negative tumors (44% = 61/138), while CIMP-low/high (1/8-8/8 methylated promoters) was significantly more common (56%) in 18q LOH-negative tumors than 18q LOH-positive tumors (41%). These relations persisted after stratification by sex, location, or the status of MSI, p53 expression (by immunohistochemistry), or KRAS/BRAF mutation. 18q LOH is correlated positively with CIMP-0 and inversely with CIMP-low and CIMP-high. Our findings provide supporting evidence for relationship between CIMP-0 and 18q LOH as well as a molecular difference between CIMP-0 and CIMP-low in colorectal cancer.

  7. q-bosons and the q-analogue quantized field

    International Nuclear Information System (INIS)

    Nelson, C.A.

    1994-01-01

    The q-analogue coherent states |z > q are used to identify physical signatures for the presence of a q-analogue quantized radiation field in the | > q classical limit where |z| is large. In this quantum-optics-like limit, the fractional uncertainties of most physical quantities (momentum, position, amplitude, phase) which characterize the quantum field are O(1). They only vanish as O(1/|z|) when q = 1. However, for the number operator, N, and the N-Hamiltonian for a free q-boson gas, H N = ℎω(N + 1/2), the fractional uncertainties do still approach zero. A signature for q-boson counting statistics is that (ΔN) 2 / → 0 as |z| → ∞. Except for its O(1) fractional uncertainty, the q-generalization of the Hermitian phase operator of Pegg and Barnett, φ q , still exhibits normal classical behavior. The standard number-phase uncertainty-relation, ΔN Δφ q = 1/2, and the approximate commutation relation, [N,φ q ] = i, still hold for the single-mode q-analogue quantized field. So, N and φ q are almost canonically conjugate operators in the |z > q classical limit. The |z > q CS's minimize this uncertainty relation for moderate |z| 2

  8. Jet production in ep collisions at low Q{sup 2} and determination of {alpha}{sub s}

    Energy Technology Data Exchange (ETDEWEB)

    Aaron, F.D. [National Institute for Physics and Nuclear Engineering (NIPNE), Bucharest (Romania); Bucharest Univ. (Romania). Faculty of Physics; Aldaya Martin, M. [DESY Hamburg (Germany); Alexa, C. [National Institute for Physics and Nuclear Engineering (NIPNE), Bucharest (RO)] (and others)

    2009-10-15

    The production of jets is studied in deep-inelastic e{sup +}p scattering at low negative four momentum transfer squared 5 < Q{sup 2} < 100 GeV{sup 2} and at inelasticity 0.2 < y < 0.7 using data recorded by the H1 detector at HERA in the years 1999 and 2000, corresponding to an integrated luminosity of 43.5 pb{sup -1}. Inclusive jet, 2-jet and 3-jet cross sections as well as the ratio of 3-jet to 2-jet cross sections are measured as a function of Q{sup 2} and jet transverse momentum. The 2-jet cross section is also measured as a function of the proton momentum fraction {xi}. The measurements are well described by perturbative quantum chromodynamics at next-to-leading order corrected for hadronisation effects and are subsequently used to extract the strong coupling {alpha}{sub s}. (orig.)

  9. Jet production in ep collisions at low Q {sup 2} and determination of {alpha}{sub s}

    Energy Technology Data Exchange (ETDEWEB)

    Aaron, F.D.; Alexa, C.; Rotaru, M.; Stoicea, G. [National Inst. for Physics and Nuclear Engineering, Bucharest (Romania); Andreev, V.; Belousov, A.; Eliseev, A.; Fomenko, A.; Gogitidze, N.; Lebedev, A.; Loktionova, N.; Malinovski, E.; Rusakov, S.; Shtarkov, L.N.; Soloviev, Y.; Vazdik, Y. [Lebedev Physical Inst., Moscow (Russian Federation); Antunovic, B.; Bartel, W.; Brandt, G.; Campbell, A.J.; Cholewa, A.; Deak, M.; Eckerlin, G.; Elsen, E.; Felst, R.; Fischer, D.J.; Fleischer, M.; Gayler, J.; Ghazaryan, S.; Glazov, A.; Gouzevitch, M.; Grell, B.R.; Haidt, D.; Helebrant, C.; Jung, H.; Katzy, J.; Kleinwort, C.; Knutsson, A.; Kosior, E.; Kraemer, M.; Krastev, K.; Kutak, K.; Levonian, S.; Lipka, K.; List, J.; Marti, Ll.; Meyer, A.B.; Meyer, H.; Meyer, J.; Niebuhr, C.; Nikiforov, A.; Olsson, J.E.; Panagoulias, I.; Papadopoulou, T.; Pitzl, D.; Placakyte, R.; Radescu, V.; Schmitt, S.; Sefkow, F.; Staykova, Z.; Steder, M.; Vargas Trevino, A.; Vinokurova, S.; Driesch, M. von den; Wissing, C.; Wuensch, E. [DESY, Hamburg (Germany); Backovic, S.; Dubak, A.; Lastovicka-Medin, G.; Picuric, I.; Raicevic, N. [Univ. of Montenegro, Podgorica (ME); Baghdasaryan, A.; Volchinski, V.; Zohrabyan, H. [Yerevan Physics Inst. (Armenia); Barrelet, E. [Universites Paris VI et VII, CNRS/IN2P3, LPNHE, Paris (France); Begzsuren, K.; Ravdandorj, T.; Tseepeldorj, B. [Inst. of Physics and Technology of the Mongolian Academy of Sciences, Ulaanbaatar (Mongolia); Bizot, J.C.; Brisson, V.; Delcourt, B.; Jacquet, M.; Li, G.; Pascaud, C.; Tran, T.H.; Zhang, Z.; Zomer, F. [Univ. Paris-Sud, CNRS/IN2P3, LAL, Orsay (France); Boudry, V.; Moreau, F.; Specka, A. [Ecole Polytechnique, CNRS/IN2P3, LLR, Palaiseau (France); Bozovic-Jelisavcic, I.; Mudrinic, M.; Pandurovic, M.; Smiljanic, I. [Vinca Inst. of Nuclear Sciences, Belgrade (RS); Bracinik, J.; Kenyon, I.R.; Newman, P.R.; Shaw-West, R.N.; Thompson, P.D. [Univ. of Birmingham, School of Physics and Astronomy (United Kingdom)] [and others

    2010-05-15

    The production of jets is studied in deep-inelastic e {sup +} p scattering at low negative four momentum transfer squared 5<Q {sup 2}<100 GeV{sup 2} and at inelasticity 0.2Q {sup 2} and jet transverse momentum. The 2-jet cross section is also measured as a function of the proton momentum fraction {xi}. The measurements are well described by perturbative quantum chromodynamics at next-to-leading order corrected for hadronisation effects and are subsequently used to extract the strong coupling {alpha}{sub s}. (orig.)

  10. Utility of the Neuropsychiatric Inventory Questionnaire (NPI-Q in the assessment of a sample of patients with Alzheimer's disease in Chile

    Directory of Open Access Journals (Sweden)

    Gada Musa

    Full Text Available ABSTRACT The Neuropsychiatric Inventory Questionnaire (NPI-Q is an informant-based instrument that measures the presence and severity of 12 Neuropsychiatric Symptoms (NPS in patients with dementia, as well as informant distress. Objective: To measure the psychometric properties of the NPI-Q and the prevalence of NPS in patients with Alzheimer's disease (AD in Chile. Methods: 53 patients with AD were assessed. Subjects were divided into two different groups: mild AD (n=26 and moderate AD (n=27. Convergent validity was estimated by correlating the outcomes of the NPI-Q with Neuropsychiatric Inventory (NPI scores and with a global cognitive efficiency test (Addenbrooke's Cognitive Examination - Revised - ACE-R. Reliability of the NPI-Q was analysed by calculating its internal consistency. Prevalence of NPS was estimated with both the NPI and NPI-Q. Results: Positive and significant correlations were observed between the NPI-Q, the NPI, and the ACE-R (r=0.730; p<0.01 and 0.315; p<0.05 respectively. The instrument displayed an adequate level of reliability (Cronbach's alpha=0.783. The most prevalent NPS were apathy/indifference (62.3% and dysphoria/depression (58.5%. Conclusion: The NPI-Q exhibited acceptable validity and reliability indicators for patients with AD in Chile, indicating that it is a suitable instrument for the routine assessment of NPS in clinical practice.

  11. UNVEILING THE UNIVERSALITY OF I-LOVE-Q RELATIONS

    Energy Technology Data Exchange (ETDEWEB)

    Sham, Y.-H.; Lin, L.-M.; Leung, P. T. [Department of Physics and Institute of Theoretical Physics, The Chinese University of Hong Kong, Hong Kong SAR (China); Chan, T. K., E-mail: yhsham@phy.cuhk.edu.hk, E-mail: chantsangkeung@gmail.com, E-mail: lmlin@phy.cuhk.edu.hk, E-mail: ptleung@phy.cuhk.edu.hk [Present address: Department of Physics, University of California at San Diego, 9500 Gilman Drive, La Jolla, CA 92093, USA. (United States)

    2015-01-10

    The recent discovery of the universal I-Love-Q relations connecting the moment of inertia, tidal deformability, and the spin-induced quadrupole moment of compact stars is intriguing and totally unexpected. In this paper, we provide numerical evidence showing that the universality can be attributed to the incompressible limit of the I-Love-Q relations. The fact that modern equations of state are stiff, with an effective adiabatic index larger than about two, above the nuclear density range is the key to establishing the universality for neutron stars and quark stars with typical compactness from about 0.1 to 0.3. On the other hand, the I-Love-Q relations of low-mass neutron stars near the minimum mass limit depend more sensitively on the underlying equation of state because these stars are composed mainly of softer matter at low densities. However, the I-Love-Q relations for low-mass quark stars can still be represented accurately by the incompressible limit. We also study the I-Love relation connecting the moment of inertia and tidal deformability analytically in Newtonian gravity and show why the I-Love-Q relation is weakly dependent on the underlying equation of state and can be attributed to its incompressible limit.

  12. Unveiling the Universality of I-Love-Q Relations

    Science.gov (United States)

    Sham, Y.-H.; Chan, T. K.; Lin, L.-M.; Leung, P. T.

    2015-01-01

    The recent discovery of the universal I-Love-Q relations connecting the moment of inertia, tidal deformability, and the spin-induced quadrupole moment of compact stars is intriguing and totally unexpected. In this paper, we provide numerical evidence showing that the universality can be attributed to the incompressible limit of the I-Love-Q relations. The fact that modern equations of state are stiff, with an effective adiabatic index larger than about two, above the nuclear density range is the key to establishing the universality for neutron stars and quark stars with typical compactness from about 0.1 to 0.3. On the other hand, the I-Love-Q relations of low-mass neutron stars near the minimum mass limit depend more sensitively on the underlying equation of state because these stars are composed mainly of softer matter at low densities. However, the I-Love-Q relations for low-mass quark stars can still be represented accurately by the incompressible limit. We also study the I-Love relation connecting the moment of inertia and tidal deformability analytically in Newtonian gravity and show why the I-Love-Q relation is weakly dependent on the underlying equation of state and can be attributed to its incompressible limit.

  13. UNVEILING THE UNIVERSALITY OF I-LOVE-Q RELATIONS

    International Nuclear Information System (INIS)

    Sham, Y.-H.; Lin, L.-M.; Leung, P. T.; Chan, T. K.

    2015-01-01

    The recent discovery of the universal I-Love-Q relations connecting the moment of inertia, tidal deformability, and the spin-induced quadrupole moment of compact stars is intriguing and totally unexpected. In this paper, we provide numerical evidence showing that the universality can be attributed to the incompressible limit of the I-Love-Q relations. The fact that modern equations of state are stiff, with an effective adiabatic index larger than about two, above the nuclear density range is the key to establishing the universality for neutron stars and quark stars with typical compactness from about 0.1 to 0.3. On the other hand, the I-Love-Q relations of low-mass neutron stars near the minimum mass limit depend more sensitively on the underlying equation of state because these stars are composed mainly of softer matter at low densities. However, the I-Love-Q relations for low-mass quark stars can still be represented accurately by the incompressible limit. We also study the I-Love relation connecting the moment of inertia and tidal deformability analytically in Newtonian gravity and show why the I-Love-Q relation is weakly dependent on the underlying equation of state and can be attributed to its incompressible limit

  14. Detuning effect study of High-Q Mobile Phone Antennas

    DEFF Research Database (Denmark)

    Bahramzy, Pevand; Pedersen, Gert F.

    2015-01-01

    Number of frequency bands that have to be covered by smart phones, are ever increasing. This broadband coverage can be obtained either by using a low-Q antenna or a high-Q tunable antenna. This study investigates high-Q antennas performance when placed in proximity of the user. This study...

  15. A New Instrument Design for Imaging Low Energy Neutral Atoms

    Science.gov (United States)

    Keller, John W.; Collier, Michael R.; Chornay, Dennis; Rozmarynowski, Paul; Getty, Stephanie; Cooper, John F.; Smith, Billy

    2007-01-01

    The MidSTAR-2 satellite, to be built at the US Naval Academy as a follow-on to the successful MidSTAR-1 satellite (http://web.ew.usna.edu/midstar/), will launch in 2011 and carry three Goddard Space Flight Center (GSFC) experiments developed under Goddard's Internal Research and Development (IRAD) program. One of these GSFC instruments, the Miniature Imager for Neutral Ionospheric atoms and Magnetospheric Electrons (MINI-ME) builds on the heritage of the Goddard-developed Low-Energy Neutral Atom (LENA) imager launched on the IMAGE spacecraft in 2000. MINI-ME features a Venetian-blind conversion surface assembly that improves both light rejection and conversion efficiency in a smaller and lighter package than LENA making this an highly effective instrument for viewing solar wind charge exchange with terrestrial and planetary exospheres. We will describe the MINI-ME prototyping effort and its science targets.

  16. The Spin Structure of 3He and the Neutron at Low Q2: A Measurement of the Generalized GDH Integrand

    Energy Technology Data Exchange (ETDEWEB)

    Sulkosky, Vincent [College of William and Mary, Williamsburg, VA (United States)

    2007-08-01

    Since the 1980's, the study of nucleon (proton or neutron) spin structure has been an active field both experimentally and theoretically. One of the primary goals of this work is to test our understanding of Quantum Chromodynamics (QCD), the fundamental theory of the strong interaction. In the high energy region of asymptotically free quarks, QCD has been verified. However, verifiable predictions in the low energy region are harder to obtain due to the complex interactions between the nucleon's constituents: quarks and gluons. In the non-pertubative regime, low-energy effective field theories such as chiral perturbation theory provide predictions for the spin structure functions in the form of sum rules. Spin-dependent sum rules such as the Gerasimov-Drell-Hearn (GDH) sum rule are important tools available to study nucleon spin structure. Originally derived for real photon absorption, the Gerasimov-Drell-Hearn (GDH) sum rule was first extended for virtual photon absorption in 1989. The extension of the sum rule provides a unique relation, valid at any momentum transfer ($Q^{2}$), that can be used to study the nucleon spin structure and make comparisons between theoretical predictions and experimental data. Experiment E97-110 was performed at the Thomas Jefferson National Accelerator Facility (Jefferson Lab) to examine the spin structure of the neutron and $^{3}$He. The Jefferson Lab longitudinally-polarized electron beam with incident energies between 1.1 and 4.4 GeV was scattered from a longitudinally or transversely polarized $^{3}$He gas target in the Hall A end station. Asymmetries and polarized cross-section differences were measured in the quasielastic and resonance regions to extract the spin structure functions $g_{1}(x,Q^{2})$ and $g_{2}(x,Q^{2})$ at low momentum transfers (0.02 $< Q^{2} <$ 0.3 GeV$^{2}$). The goal of the experiment was to perform a precise measurement of the $Q^{2}$ dependence of the extended GDH integral and of the moments of

  17. Bridging ultrahigh-Q devices and photonic circuits

    Science.gov (United States)

    Yang, Ki Youl; Oh, Dong Yoon; Lee, Seung Hoon; Yang, Qi-Fan; Yi, Xu; Shen, Boqiang; Wang, Heming; Vahala, Kerry

    2018-05-01

    Optical microresonators are essential to a broad range of technologies and scientific disciplines. However, many of their applications rely on discrete devices to attain challenging combinations of ultra-low-loss performance (ultrahigh Q) and resonator design requirements. This prevents access to scalable fabrication methods for photonic integration and lithographic feature control. Indeed, finding a microfabrication bridge that connects ultrahigh-Q device functions with photonic circuits is a priority of the microcavity field. Here, an integrated resonator having a record Q factor over 200 million is presented. Its ultra-low-loss and flexible cavity design brings performance to integrated systems that has been the exclusive domain of discrete silica and crystalline microcavity devices. Two distinctly different devices are demonstrated: soliton sources with electronic repetition rates and high-coherence/low-threshold Brillouin lasers. This multi-device capability and performance from a single integrated cavity platform represents a critical advance for future photonic circuits and systems.

  18. On the q-exponential of matrix q-Lie algebras

    Directory of Open Access Journals (Sweden)

    Ernst Thomas

    2017-01-01

    Full Text Available In this paper, we define several new concepts in the borderline between linear algebra, Lie groups and q-calculus.We first introduce the ring epimorphism r, the set of all inversions of the basis q, and then the important q-determinant and corresponding q-scalar products from an earlier paper. Then we discuss matrix q-Lie algebras with a modified q-addition, and compute the matrix q-exponential to form the corresponding n × n matrix, a so-called q-Lie group, or manifold, usually with q-determinant 1. The corresponding matrix multiplication is twisted under τ, which makes it possible to draw diagrams similar to Lie group theory for the q-exponential, or the so-called q-morphism. There is no definition of letter multiplication in a general alphabet, but in this article we introduce new q-number systems, the biring of q-integers, and the extended q-rational numbers. Furthermore, we provide examples of matrices in suq(4, and its corresponding q-Lie group. We conclude with an example of system of equations with Ward number coeficients.

  19. Retrospective diagnosis of Q fever in a country abattoir by the use of specific IgM globulin estimations

    Energy Technology Data Exchange (ETDEWEB)

    Murphy, A.M.; Hunt, J.G.

    1981-10-03

    Twenty-two cases of pyrexial illness which occurred amongst workers in a country abattoir were investigated retrospectively for Q fever, brucellosis, and leptospirosis. In 18, the illness was shown to be Q fever. No diagnoses were established for the other four. The demonstration of circulating Q-fever-specific IgM globulin was instrumental in establishing the diagnosis in many of the cases.

  20. Spin asymmetries $A_1$ of the proton and the deuteron in the low $x$ and low $Q^2$ region from polarized high energy muon scattering

    CERN Document Server

    AUTHOR|(CDS)2067425; Arvidson, A; Badelek, B; Baum, G; Berglund, P; Betev, L; De Botton, N R; Bradamante, Franco; Bravar, A; Bültmann, S; Burtin, E; Crabb, D; Cranshaw, J; Çuhadar-Dönszelmann, T; Dalla Torre, S; Van Dantzig, R; Derro, B R; Deshpande, A A; Dhawan, S K; Dulya, C M; Eichblatt, S; Fasching, D; Feinstein, F; Fernández, C; Frois, Bernard; Gallas, A; Garzón, J A; Gilly, H; Giorgi, M A; von Goeler, E; Görtz, S; Gracia, G; De Groot, N; Grosse-Perdekamp, M; Haft, K; Von Harrach, D; Hasegawa, T; Hautle, P; Hayashi, N; Heusch, C A; Horikawa, N; Hughes, V W; Igo, G; Ishimoto, S; Iwata, T; Kabuss, E M; Karev, A G; Kessler, H J; Ketel, T; Kiryluk, J; Kiselev, Yu F; Krämer, Dietrich; Kröger, W; Kurek, K; Kyynäräinen, J; Lamanna, M; Landgraf, U; Le Goff, J M; Lehár, F; de Lesquen, A; Lichtenstadt, J; Litmaath, M; Magnon, A; Mallot, G K; Marie, F; Martin, A; Martino, J; Matsuda, T; Mayes, B W; McCarthy, J S; Medved, K S; Meyer, W T; Van Middelkoop, G; Miller, D; Miyachi, Y; Mori, K; Moromisato, J H; Nassalski, J P; Niinikoski, T O; Oberski, J; Ogawa, A; Ozben, C; Pereira, H; Perrot-Kunne, F; Peshekhonov, V D; Piegaia, R; Pinsky, L; Platchkov, S K; Pló, M; Pose, D; Postma, H; Pretz, J; Puntaferro, R; Rädel, G; Reicherz, G; Roberts, J; Rodríguez, M; Rondio, Ewa; Sabo, I; Saborido, J; Sandacz, A; Savin, I A; Schiavon, R P; Sichtermann, E P; Simeoni, F; Smirnov, G I; Staude, A; Steinmetz, A; Stiegler, U; Stuhrmann, H B; Tessarotto, F; Thers, D; Tlaczala, W; Tripet, A; Ünel, G; Velasco, M; Vogt, J; Voss, Rüdiger; Whitten, C; Willumeit, R; Windmolders, R; Wislicki, W; Witzmann, A; Zanetti, A M; Zaremba, K; Zhao, J

    1999-01-01

    We present the results of the spin asymmetries $A_1$ of the proton and the deuteron in the kinematic region extending down to $x=6\\cdot 10^{-5}$ and $Q^2=0.01$ GeV$^2$. The data were taken with a dedicated low $x$ trigger, which required hadron detection in addition to the scattered muon, so as to reduce the background at low $x$. The results complement our previous measurements and the two sets are consistent in the overlap region. No sig\\-ni\\-fi\\-cant spin effects are found in the newly explored region.

  1. Heavy-Quark Symmetry Implies Stable Heavy Tetraquark Mesons Q_{i}Q_{j}q[over ¯]_{k}q[over ¯]_{l}.

    Science.gov (United States)

    Eichten, Estia J; Quigg, Chris

    2017-11-17

    For very heavy quarks Q, relations derived from heavy-quark symmetry predict the existence of novel narrow doubly heavy tetraquark states of the form Q_{i}Q_{j}q[over ¯]_{k}q[over ¯]_{l} (subscripts label flavors), where q designates a light quark. By evaluating finite-mass corrections, we predict that double-beauty states composed of bbu[over ¯]d[over ¯], bbu[over ¯]s[over ¯], and bbd[over ¯]s[over ¯] will be stable against strong decays, whereas the double-charm states ccq[over ¯]_{k}q[over ¯]_{l}, mixed beauty+charm states bcq[over ¯]_{k}q[over ¯]_{l}, and heavier bbq[over ¯]_{k}q[over ¯]_{l} states will dissociate into pairs of heavy-light mesons. Observation of a new double-beauty state through its weak decays would establish the existence of tetraquarks and illuminate the role of heavy color-antitriplet diquarks as hadron constituents.

  2. GDH sum rule measurement at low Q2

    International Nuclear Information System (INIS)

    Bianchi, N.

    1996-01-01

    The Gerasimov-Drell-Hearn (GDH) sum rule is based on a general dispersive relation for the forward Compton scattering. Multipole analysis suggested the possible violation of the sum rule. Some propositions have been made to modify the original GDH expression. An effort is now being made in several laboratories to shred some light on this topic. The purposes of the different planned experiments are briefly presented according to their Q 2 range

  3. Transverse momentum of charged particles in low-Q{sup 2} DIS at HERA

    Energy Technology Data Exchange (ETDEWEB)

    Grebenyuk, Anastasia

    2012-04-15

    In this thesis, measurement of the transverse momentum and pseudorapidity distributions of charged particles in deep-inelastic ep scattering at a centre of mass energy of {radical}(s)=319 GeV are presented. The analysis is based on data collected by the H1 detector in 2006, corresponding to an integrated luminosity of 88.64 pb{sup -1}. The phase space of the measurement is defined by 5<Q{sup 2}<100 GeV{sup 2} and 0.05Q{sup 2}. The measured distributions are compared to predictions from different Monte Carlo generators using different approaches to simulate the parton cascade. The measurement shows the importance of parton emissions unordered in transverse momentum. A QCD model, exhibiting this feature, such as the BFKL-like colour dipole model is best in the description of the data, whereas a model generating emissions according to the DGLAP approach undershoots the data at low Bjorken-x. It is shown that the region of small transverse momenta is primarily affected by the hadronisation process, whereas the region of large transverse momenta is mainly driven by perturbative parton radiation. (orig.)

  4. Low-cost and disposable sensors for the simultaneous determination of coenzyme Q10 and α-lipoic acid using manganese (IV) oxide-modified screen-printed graphene electrodes.

    Science.gov (United States)

    Charoenkitamorn, Kanokwan; Chaiyo, Sudkate; Chailapakul, Orawon; Siangproh, Weena

    2018-04-03

    In this work, for the first time, manganese (IV) oxide-modified screen-printed graphene electrodes (MnO 2 /SPGEs) were developed for the simultaneous electrochemical detection of coenzyme Q10 (CoQ10) and α-lipoic acid (ALA). This sensor exhibits attractive benefits such as simplicity, low production costs, and disposability. Cyclic voltammetry (CV) was used to characterize the electrochemical behavior of the analyte and investigate the capacitance and electroactive surface area of the unmodified and modified electrode surfaces. The electrochemical behavior of CoQ10 and ALA on MnO 2 /SPGEs was also discussed. Additionally, square wave anodic stripping voltammetry (SWASV) was used for the quantitative determination of CoQ10 and ALA. Under optimal conditions, the obtained signals are linear in the concentration range from 2.0 to 75.0 μg mL -1 for CoQ10 and 0.3-25.0 μg mL -1 for ALA. The low limits of detection (LODs) were found to be 0.56 μg mL -1 and 0.088 μg mL -1 for CoQ10 and ALA, respectively. Moreover, we demonstrated the utility and applicability of the MnO 2 /SPGE sensor through simultaneous measurements of CoQ10 and ALA in dietary supplements. The sensor provides high accuracy measurements, exhibiting its high potential for practical applications. Copyright © 2017 Elsevier B.V. All rights reserved.

  5. 18q loss of heterozygosity in microsatellite stable colorectal cancer is correlated with CpG island methylator phenotype-negative (CIMP-0 and inversely with CIMP-low and CIMP-high

    Directory of Open Access Journals (Sweden)

    Kirkner Gregory J

    2007-05-01

    Full Text Available Abstract Background: The CpG island methylator phenotype (CIMP with widespread promoter methylation is a distinct epigenetic phenotype in colorectal cancer, associated with microsatellite instability-high (MSI-high and BRAF mutations. 18q loss of heterozygosity (LOH commonly present in colorectal cancer with chromosomal instability (CIN is associated with global hypomethylation in tumor cell. A recent study has shown an inverse correlation between CIN and CIMP (determined by MINTs, p16, p14 and MLH1 methylation in colorectal cancer. However, no study has examined 18q LOH in relation to CIMP-high, CIMP-low (less extensive promoter methylation and CIMP-0 (CIMP-negative, determined by quantitative DNA methylation analysis. Methods: Utilizing MethyLight technology (real-time PCR, we quantified DNA methylation in 8 CIMP-specific promoters {CACNA1G, CDKN2A (p16, CRABP1, IGF2, MLH1, NEUROG1, RUNX3 and SOCS1} in 758 non-MSI-high colorectal cancers obtained from two large prospective cohorts. Using four 18q microsatellite markers (D18S55, D18S56, D18S67 and D18S487 and stringent criteria for 18q LOH, we selected 374 tumors (236 LOH-positive tumors with ≥ 2 markers showing LOH; and 138 LOH-negative tumors with ≥ 3 informative markers and no LOH. Results: CIMP-0 (0/8 methylated promoters was significantly more common in 18q LOH-positive tumors (59% = 139/236, p = 0.002 than 18q LOH-negative tumors (44% = 61/138, while CIMP-low/high (1/8–8/8 methylated promoters was significantly more common (56% in 18q LOH-negative tumors than 18q LOH-positive tumors (41%. These relations persisted after stratification by sex, location, or the status of MSI, p53 expression (by immunohistochemistry, or KRAS/BRAF mutation. Conclusion: 18q LOH is correlated positively with CIMP-0 and inversely with CIMP-low and CIMP-high. Our findings provide supporting evidence for relationship between CIMP-0 and 18q LOH as well as a molecular difference between CIMP-0 and CIMP-low in

  6. q-Virasoro algebra, q-conformal dimensions and free q-superstring

    International Nuclear Information System (INIS)

    Chaichian, M.

    1996-01-01

    The commutators of standard Virasoro generators and fields generate various representations of the centreless Virasoro algebra depending on a conformal dimension J of the field in question (J is related to the Bargmann index of SU(1,1) generated by L m , m=0,±1). We introduce the notion of q-conformal dimension for various oscillator realizations of q-deformed Virasoro (super)algebras proposed earlier. We use the field theoretical approach introduced recently in which the q-Virasoro currents L α (z) are expressed as Schwinger-like point-split normally ordered quadratic expressions in elementary fields. We extend this approach and probe the elementary fields A(z) (the q-superstring coordinate, momentum and fermionic field) and their powers by the q-Virasoro generators L α m (i.e. we calculate the commutators [L α m ,A(z)]) and show that to all of them can be assigned just the standard non-deformed conformal dimension. (orig.)

  7. Development of new instrumentation for epithermal neutron scattering at very low angles

    International Nuclear Information System (INIS)

    Tardocchi, M.; Pietropaolo, A.; Andreani, C.; Gorini, G.; Perelli-Cippo, E.; Rhodes, N.J.; Schooneveld, E.M.; Senesi, R.

    2004-01-01

    New perspectives for epithermal neutron spectroscopy are opened up by the recent developments of Resonance Detectors (RD) for inverse geometry time-of-flight spectrometers at pulsed neutron sources. The RD is based on the combination of an analyser foil used as neutron-to-gamma converter and a suitable photon detector. Here, we report on the state of the RD which is based on a YAP scintillator viewing a natural uranium analyser foil. The response of the YAP detector to the radiative capture γ emission from the uranium analyser foil has been characterized with a bi-parametric measurement of a reference Pb sample, which allowed simultaneous measurements of both neutron time-of-flight and γ pulse height (energy) spectra. The analysis of the γ pulse height and neutron time-of-flight spectra permitted to identify the signal and background components. These measurements showed that a significant improvement in the signal-to-background ratio can be achieved by setting a lower level discrimination on the photon energy at about 600keV. The first application of RD is the Very Low Angle Detector Bank (VLAD) which is planned to be installed in the next three years as an upgrade of the VESUVIO spectrometer, at the ISIS pulsed neutron source. VLAD will extend the (q,ω) kinematical to low wave vector transfers (q10A-1) coupled to high-energy transfers (-bar ω>1eV), which is still unexplored by neutron scattering experiments. The first measurements obtained on an ice sample with a VLAD prototype consisting of four RD units are presented here

  8. Development of new instrumentation for epithermal neutron scattering at very low angles

    Energy Technology Data Exchange (ETDEWEB)

    Tardocchi, M. [INFM, UdR Milano-Bicocca and Dipartimento di Fisica ' G.Occhialini' , Universita degli Studi di Milano-Bicocca, Pizza Della Scienza 3, Milan 20126 (Italy)]. E-mail: marco.tardocchi@mib.infn.it; Pietropaolo, A. [Dipartimento di Fisica, Universita degli Studi di Roma Tor Vergata and INFM, UdR Roma Tor Vergata, Rome (Italy); Andreani, C. [Dipartimento di Fisica, Universita degli Studi di Roma Tor Vergata and INFM, UdR Roma Tor Vergata, Rome (Italy); Gorini, G. [INFM, UdR Milano-Bicocca and Dipartimento di Fisica ' G.Occhialini' , Universita degli Studi di Milano-Bicocca, Pizza Della Scienza 3, Milan 20126 (Italy); Perelli-Cippo, E. [INFM, UdR Milano-Bicocca and Dipartimento di Fisica ' G.Occhialini' , Universita degli Studi di Milano-Bicocca, Pizza Della Scienza 3, Milan 20126 (Italy); Rhodes, N.J. [Isis Facility, Rutherford Appleton Laboratory, Chilton, Didcot (United Kingdom); Schooneveld, E.M. [Isis Facility, Rutherford Appleton Laboratory, Chilton, Didcot (United Kingdom); Senesi, R. [Dipartimento di Fisica, Universita degli Studi di Roma Tor Vergata and INFM, UdR Roma Tor Vergata, Rome (Italy)

    2004-12-11

    New perspectives for epithermal neutron spectroscopy are opened up by the recent developments of Resonance Detectors (RD) for inverse geometry time-of-flight spectrometers at pulsed neutron sources. The RD is based on the combination of an analyser foil used as neutron-to-gamma converter and a suitable photon detector. Here, we report on the state of the RD which is based on a YAP scintillator viewing a natural uranium analyser foil. The response of the YAP detector to the radiative capture {gamma} emission from the uranium analyser foil has been characterized with a bi-parametric measurement of a reference Pb sample, which allowed simultaneous measurements of both neutron time-of-flight and {gamma} pulse height (energy) spectra. The analysis of the {gamma} pulse height and neutron time-of-flight spectra permitted to identify the signal and background components. These measurements showed that a significant improvement in the signal-to-background ratio can be achieved by setting a lower level discrimination on the photon energy at about 600keV. The first application of RD is the Very Low Angle Detector Bank (VLAD) which is planned to be installed in the next three years as an upgrade of the VESUVIO spectrometer, at the ISIS pulsed neutron source. VLAD will extend the (q,{omega}) kinematical to low wave vector transfers (q10A-1) coupled to high-energy transfers (-bar {omega}>1eV), which is still unexplored by neutron scattering experiments. The first measurements obtained on an ice sample with a VLAD prototype consisting of four RD units are presented here.

  9. Jet production in ep collisions at low Q 2 and determination of αs

    International Nuclear Information System (INIS)

    Aaron, F.D.; Alexa, C.; Rotaru, M.; Stoicea, G.; Andreev, V.; Belousov, A.; Eliseev, A.; Fomenko, A.; Gogitidze, N.; Lebedev, A.; Loktionova, N.; Malinovski, E.; Rusakov, S.; Shtarkov, L.N.; Soloviev, Y.; Vazdik, Y.; Antunovic, B.; Bartel, W.; Brandt, G.; Campbell, A.J.; Cholewa, A.; Deak, M.; Eckerlin, G.; Elsen, E.; Felst, R.; Fischer, D.J.; Fleischer, M.; Gayler, J.; Ghazaryan, S.; Glazov, A.; Gouzevitch, M.; Grell, B.R.; Haidt, D.; Helebrant, C.; Jung, H.; Katzy, J.; Kleinwort, C.; Knutsson, A.; Kosior, E.; Kraemer, M.; Krastev, K.; Kutak, K.; Levonian, S.; Lipka, K.; List, J.; Marti, Ll.; Meyer, A.B.; Meyer, H.; Meyer, J.; Niebuhr, C.; Nikiforov, A.; Olsson, J.E.; Panagoulias, I.; Papadopoulou, T.; Pitzl, D.; Placakyte, R.; Radescu, V.; Schmitt, S.; Sefkow, F.; Staykova, Z.; Steder, M.; Vargas Trevino, A.; Vinokurova, S.; Driesch, M. von den; Wissing, C.; Wuensch, E.; Backovic, S.; Dubak, A.; Lastovicka-Medin, G.; Picuric, I.; Raicevic, N.; Baghdasaryan, A.; Volchinski, V.; Zohrabyan, H.; Barrelet, E.; Begzsuren, K.; Ravdandorj, T.; Tseepeldorj, B.; Bizot, J.C.; Brisson, V.; Delcourt, B.; Jacquet, M.; Li, G.; Pascaud, C.; Tran, T.H.; Zhang, Z.; Zomer, F.; Boudry, V.; Moreau, F.; Specka, A.; Bozovic-Jelisavcic, I.; Mudrinic, M.; Pandurovic, M.; Smiljanic, I.; Bracinik, J.; Kenyon, I.R.; Newman, P.R.; Shaw-West, R.N.; Thompson, P.D.; Brinkmann, M.; Habib, S.; List, B.; Pokorny, B.; Toll, T.; Bruncko, D.; Cerny, V.; Ferencei, J.; Murin, P.; Tomasz, F.; Bunyatyan, A.; Buschhorn, G.; Chekelian, V.; Dossanov, A.; Grindhammer, G.; Kiesling, C.; Kogler, R.; Liptaj, A.; Raspiareza, A.; Shushkevich, S.; Bystritskaya, L.; Efremenko, V.; Fedotov, A.; Kropivnitskaya, A.; Lubimov, V.; Ozerov, D.; Petrukhin, A.; Rostovtsev, A.; Zhokin, A.; Cantun Avila, K.B.; Contreras, J.G.; Ruiz Tabasco, J.E.; Cerny, K.; Pejchal, O.; Polifka, R.; Salek, D.; Valkarova, A.; Zacek, J.; Coughlan, J.A.; Morris, J.V.; Sankey, D.P.C.; Cozzika, G.; Feltesse, J.; Perez, E.; Schoeffel, L.; Cvach, J.; Reimer, P.; Zalesak, J.; Dainton, J.B.; Gabathuler, E.; Greenshaw, T.; Klein, M.; Kluge, T.; Kretzschmar, J.; Laycock, P.; Maxfield, S.J.; Mehta, A.; Patel, G.D.; Rahmat, A.J.; Daum, K.; Meyer, H.; Delvax, J.; Wolf, E.A. de; Favart, L.; Hreus, T.; Janssen, X.; Marage, P.; Mozer, M.U.; Roland, B.; Roosen, R.; Sunar, D.; Sykora, T.; Mechelen, P. van; Diaconu, C.; Hoffmann, D.; Sauvan, E.; Trinh, T.N.; Vallee, C.; Dodonov, V.; Povh, B.; Egli, S.; Hildebrandt, M.; Horisberger, R.; Falkiewicz, A.; Goerlich, L.; Mikocki, S.; Milcewicz-Mika, I.; Nowak, G.; Sopicki, P.; Turnau, J.; Glushkov, I.; Henschel, H.; Hiller, K.H.; Kostka, P.; Lange, W.; Naumann, T.; Piec, S.; Grab, C.; Zimmermann, T.; Henderson, R.C.W.; Sloan, T.; Hennekemper, E.; Herbst, M.; Jung, A.W.; Krueger, K.; Lendermann, V.; Schultz-Coulon, H.C.; Urban, K.; Herrera, G.; Lopez-Fernandez, R.; Joensson, L.; Osman, S.; Kapichine, M.; Makankine, A.; Morozov, A.; Nikitin, D.; Palichik, V.; Spaskov, V.; Tchoulakov, V.; Landon, M.P.J.; Rizvi, E.; Thompson, G.; Traynor, D.; Martyn, H.U.; Mueller, K.; Nowak, K.; Robmann, P.; Straumann, U.; Truoel, P.; Sauter, M.; Schoening, A.; South, D.; Wegener, D.; Stella, B.; Tsakov, I.

    2010-01-01

    The production of jets is studied in deep-inelastic e + p scattering at low negative four momentum transfer squared 5 2 2 and at inelasticity 0.2 -1 . Inclusive jet, 2-jet and 3-jet cross sections as well as the ratio of 3-jet to 2-jet cross sections are measured as a function of Q 2 and jet transverse momentum. The 2-jet cross section is also measured as a function of the proton momentum fraction ξ. The measurements are well described by perturbative quantum chromodynamics at next-to-leading order corrected for hadronisation effects and are subsequently used to extract the strong coupling α s . (orig.)

  10. Planck early results. V. The Low Frequency Instrument data processing

    DEFF Research Database (Denmark)

    Poutanen, T.; Lähteenmäki, A.; León-Tavares, J.

    2011-01-01

    We describe the processing of data from the Low Frequency Instrument (LFI) used in production of the Planck Early Release Compact Source Catalogue (ERCSC). In particular, we discuss the steps involved in reducing the data from telemetry packets to cleaned, calibrated, time-ordered data (TOD) and ...... statistical uncertainties on LFI and Planck products are also produced. Main beams are estimated down to the ≈ -10dB level using Jupiter transits, which are also used for geometrical calibration of the focal plane. © ESO, 2011....

  11. Low-voltage Power Supply Subsystem for a Sub-Orbital Particle Physic Instrument

    Directory of Open Access Journals (Sweden)

    Hector Hugo Silva Lopez

    2014-01-01

    Full Text Available The Japanese Experiment Module–Extreme Universe Space Observatory (JEM-EUSO is a wide-field (+/-~30°of aperture 2.5m refractor telescope to be installed in the International Space Station (ISS. The instrument looks downward from its orbit, into Earth’s atmosphere, with the main objective of observing ultra-violet (UV fluorescence light generated by Ultra-High Energy Cosmic Rays (UHECR extensive air showers (EAS. It is a frontier particle-physics experiment, the first of its kind. The validation of the technical readiness level of such a complex and unique instrument requires prototypes at several levels of integration. At the highest level, the EUSO-Balloon instrument has been conceived, through French space agency (CNES. At a smaller scale and in suborbital flight, EUSO-Balloon integrates all the sub-systems of the full space JEM-EUSO telescope, allowing end-to-end testing of hardware and interfaces, and to probing the global detection chain and strategy, while improving at the same time our knowledge of atmospheric and terrestrial UV background. EUSO-Balloon will be flown by CNES for the first time from Timmins, Canada; on spring 2014.This article presents the low-voltage power supply (LVPS subsystem development for the EUSO-Balloon instrument. This LVPS is the fully operational prototype for the space instrument JEM-EUSO. Besides design and construction, all performance tests and integration results with the other involved subsystems are shown.

  12. Instrumentation for the study of low emittance tuning and beam dynamics at CESR

    Science.gov (United States)

    Billing, M. G.; Dobbins, J. A.; Forster, M. J.; Kreinick, D. L.; Meller, R. E.; Peterson, D. P.; Ramirez, G. A.; Rendina, M. C.; Rider, N. T.; Sagan, D. C.; Shanks, J.; Sikora, J. P.; Stedinger, M. G.; Strohman, C. R.; Williams, H. A.; Palmer, M. A.; Holtzapple, R. L.; Flanagan, J.

    2017-11-01

    The Cornell Electron-positron Storage Ring (CESR) has been converted from a High Energy Physics electron-positron collider to operate as a dedicated synchrotron light source for the Cornell High Energy Synchrotron Source (CHESS) and to conduct accelerator physics research as a test accelerator, capable of studying topics relevant to future damping rings, colliders and light sources. Some of the specific topics that were targeted for the initial phase of operation of the storage ring in this mode for CESR as a Test Accelerator (CesrTA) included 1) tuning techniques to produce low emittance beams, 2) the study of electron cloud development in a storage ring and 3) intra-beam scattering effects. The complete conversion of CESR to CesrTA occurred over a several year period, described elsewhere [1-3]. In addition to instrumentation for the storage ring, which was created for CesrTA, existing instrumentation was modified to facilitate the entire range of investigations to support these studies. Procedures were developed, often requiring coordinated measurements among different instruments [4]. This paper describes the instruments utilized for the study of beam dynamics during the operation of CesrTA. The treatment of these instruments will remain fairly general in this paper as it focusses on an overview of the instruments themselves. Their interaction and inter-relationships during sequences of observations is found in a companion paper describing the associated measurement techniques. More detailed descriptions and detailed operational performance for some of the instrumentation may be found elsewhere and these will be referenced in the related sections of this paper.

  13. q-Sumudu transforms of q-analogues of Bessel functions.

    Science.gov (United States)

    Uçar, Faruk

    2014-01-01

    The main purpose of this paper is to evaluate q-Sumudu transforms of a product of q-Bessel functions. Interesting special cases of theorems are also discussed. Further, the results proved in this paper may find certain applications of q-Sumudu transforms to the solutions of the q-integrodifferential equations involving q-Bessel functions. The results may help to extend the q-theory of orthogonal functions.

  14. A Low-Noise CMOS THz Imager Based on Source Modulation and an In-Pixel High-Q Passive Switched-Capacitor N-Path Filter

    Science.gov (United States)

    Boukhayma, Assim; Dupret, Antoine; Rostaing, Jean-Pierre; Enz, Christian

    2016-01-01

    This paper presents the first low noise complementary metal oxide semiconductor (CMOS) terahertz (THz) imager based on source modulation and in-pixel high-Q filtering. The 31×31 focal plane array has been fully integrated in a 0.13μm standard CMOS process. The sensitivity has been improved significantly by modulating the active THz source that lights the scene and performing on-chip high-Q filtering. Each pixel encompass a broadband bow tie antenna coupled to an N-type metal-oxide-semiconductor (NMOS) detector that shifts the THz radiation, a low noise adjustable gain amplifier and a high-Q filter centered at the modulation frequency. The filter is based on a passive switched-capacitor (SC) N-path filter combined with a continuous-time broad-band Gm-C filter. A simplified analysis that helps in designing and tuning the passive SC N-path filter is provided. The characterization of the readout chain shows that a Q factor of 100 has been achieved for the filter with a good matching between the analytical calculation and the measurement results. An input-referred noise of 0.2μV RMS has been measured. Characterization of the chip with different THz wavelengths confirms the broadband feature of the antenna and shows that this THz imager reaches a total noise equivalent power of 0.6 nW at 270 GHz and 0.8 nW at 600 GHz. PMID:26950131

  15. A Low-Noise CMOS THz Imager Based on Source Modulation and an In-Pixel High-Q Passive Switched-Capacitor N-Path Filter.

    Science.gov (United States)

    Boukhayma, Assim; Dupret, Antoine; Rostaing, Jean-Pierre; Enz, Christian

    2016-03-03

    This paper presents the first low noise complementary metal oxide semiconductor (CMOS) deletedCMOS terahertz (THz) imager based on source modulation and in-pixel high-Q filtering. The 31 × 31 focal plane array has been fully integrated in a 0 . 13 μ m standard CMOS process. The sensitivity has been improved significantly by modulating the active THz source that lights the scene and performing on-chip high-Q filtering. Each pixel encompass a broadband bow tie antenna coupled to an N-type metal-oxide-semiconductor (NMOS) detector that shifts the THz radiation, a low noise adjustable gain amplifier and a high-Q filter centered at the modulation frequency. The filter is based on a passive switched-capacitor (SC) N-path filter combined with a continuous-time broad-band Gm-C filter. A simplified analysis that helps in designing and tuning the passive SC N-path filter is provided. The characterization of the readout chain shows that a Q factor of 100 has been achieved for the filter with a good matching between the analytical calculation and the measurement results. An input-referred noise of 0 . 2 μ V RMS has been measured. Characterization of the chip with different THz wavelengths confirms the broadband feature of the antenna and shows that this THz imager reaches a total noise equivalent power of 0 . 6 nW at 270 GHz and 0 . 8 nW at 600 GHz.

  16. V4: The Small Angle Scattering Instrument (SANS at BER II

    Directory of Open Access Journals (Sweden)

    Uwe Keiderling

    2016-11-01

    Full Text Available V4 is a small-angle neutron scatting instrument with an accessible range of scattering vector 0.01 nm-1 < Q < 8.5 nm-1. Outstanding features of the instrument are the polarized neutron option and the list mode data acquisition, allowing for time-resolved measurements with µs time resolution.

  17. The Psychopathy Q-Sort. Construct Validity Evidence in a Nonclinical Sample

    Science.gov (United States)

    Fowler, Katherine A.; Lilienfeld, Scott O.

    2007-01-01

    Scant research has examined the validity of instruments that permit observer ratings of psychopathy. Using a nonclinical (undergraduate) sample, the authors examined the associations between both self- and observer ratings on a psychopathy prototype (Psychopathy Q-Sort, PQS) and widely used measures of psychopathy, antisocial behavior, and…

  18. Triple quadrupole tandem mass spectrometry: A real alternative to high resolution magnetic sector instrument for the analysis of polychlorinated dibenzo-p-dioxins, furans and dioxin-like polychlorinated biphenyls.

    Science.gov (United States)

    García-Bermejo, Ángel; Ábalos, Manuela; Sauló, Jordi; Abad, Esteban; González, María José; Gómara, Belén

    2015-08-19

    This paper reports on the optimisation, characterisation, validation and applicability of gas chromatography coupled to triple quadrupole mass spectrometry in its tandem operation mode (GC-QqQ(MS/MS) for the quantification of polychlorinated dibenzo-p-dioxins and furans (PCDD/Fs, dioxins) and dioxin-like polychlorinated biphenyls (DL-PCBs) in environmental and food matrices. MS/MS parameters were selected to achieve the high sensitivity and selectivity required for the analysis of this type of compounds and samples. Good repeatability for areas (RSD = 1-10%, for PCDD/Fs and DL-PCBs) and for ion transition ratios (RSD = 0.3-10%, for PCDD/Fs, and 0.2-15%, for DL-PCBs) and low instrumental limits of detection, 0.07-0.75 pg μL(-1) (for dioxins) and 0.05-0.63 pg μL(-1) (for DL-PCBs), were obtained. A comparative study of the congener specific determination using both GC-QqQ(MS/MS) and gas chromatography-high resolution mass spectrometry (GC-HRMS) was also performed by analysing several fortified samples and certified reference materials (CRMs) with low (feed and foodstuffs), median (sewage sludge) and high (fly ash) toxic equivalency (TEQ) concentration levels, i.e. 0.60, 1.83, 72.9 and 3609 pg WHO-TEQ(PCDD/Fs) g(-1). The agreement between the results obtained for the total TEQs (dioxins) on GC-QqQ(MS/MS) and GC-HRMS in all the investigated samples were within the range of ±4%, and that of DL-PCBs at concentration levels of 0.84 pg WHO-TEQs (DL-PCBs) g(-1), in the case of feedstuffs, was 0.11%. Both instrumental methods have similar and comparable linearity, precision and accuracy. The GC-QqQ(MS/MS) sensitivity, lower than that of GC-HRMS, is good enough (iLODs in the down to low pg levels) to detect the normal concentrations of these compounds in food and environmental samples. These results make GC-QqQ(MS/MS) suitable for the quantitative analysis of dioxins and DL-PCBs and a real alternative tool to the reference sector HRMS instruments. Copyright © 2015 Elsevier

  19. Evaluation of the hybrid III and Q-series pediatric ATD upper neck loads as compared to pediatric volunteers in low-speed frontal crashes.

    Science.gov (United States)

    Seacrist, Thomas; Mathews, Emily A; Balasubramanian, Sriram; Maltese, Matthew R; Arbogast, Kristy B

    2013-11-01

    Debate exists in the automotive community regarding the validity of the pediatric ATD neck response and corresponding neck loads. Previous research has shown that the pediatric ATDs exhibit hyper-flexion and chin-to-chest contact resulting in overestimations of neck loads and neck injury criteria. Our previous work comparing the kinematics of the Hybrid III and Q-series 6 and 10-year-old ATDs to pediatric volunteers in low-speed frontal sled tests revealed decreased ATD cervical and thoracic spine excursions. These kinematic differences may contribute to the overestimation of upper neck loads by the ATD. The current study compared upper neck loads of the Hybrid III and Q-series 6 and 10-year-old ATDs against size-matched male pediatric volunteers in low-speed frontal sled tests. A 3-D near-infrared target tracking system quantified the position of markers on the ATD and pediatric volunteers (head top, nasion, bilateral external auditory meatus). Shear force (F x ), axial force (F z ), bending moment (M y ), and head angular acceleration ([Formula: see text]) were calculated about the upper neck using standard equations of motion. In general, the ATDs underestimated axial force and overestimated bending moment compared to the human volunteers. The Hybrid III 6, Q6, and Q10 exhibited reduced head angular acceleration and modest increases in upper neck shear compared to the pediatric volunteers. The reduction in axial force and bending moment has important implications for neck injury predictions as both are used when calculating N ij . These analyses provide insight into the biofidelity of the pediatric ATD upper neck loads in low-speed crash environments.

  20. Translocation t(11;14 (q13;q32 and genomic imbalances in multi-ethnic multiple myeloma patients: a Malaysian study

    Directory of Open Access Journals (Sweden)

    Ivyna Bong Pau Ni

    2012-09-01

    Full Text Available More than 50% of myeloma cases have normal karyotypes under conventional cytogenetic analysis due to low mitotic activity and content of plasma cells in the bone marrow. We used a polymerase chain reaction (PCR-based translocation detection assay to detect BCL1/JH t(11;14 (q13;q32 in 105 myeloma patients, and randomly selected 8 translocation positive samples for array comparative genomic hybridization (aCGH analysis. Our findings revealed 14.3% of myeloma samples were positive for BCL1/JH t(11;14 (q13;q32 translocation (n=15 of 105. We found no significant correlation between this translocation with age (P=0.420, gender (P=0.317, ethnicity (P=0.066 or new/relapsed status of multiple myeloma (P=0.412 at 95% confidence interval level by x2 test. In addition, aCGH results showed genomic imbalances in all samples analyzed. Frequent chromosomal gains were identified at regions 1q, 2q, 3p, 3q, 4p, 4q, 5q, 7q, 9q, 11q, 13q, 15q, 21q, 22q and Xq, while chromosomal losses were detected at 4q and 14q. Copy number variations at genetic loci that contain NAMPT, IVNS1ABP and STK17B genes are new findings that have not previously been reported in myeloma patients. Besides fluorescence in situ hybridization, PCR is another rapid, sensitive and simple technique that can be used for detecting BCL1/JH t(11;14(q13;q32 translocation in multiple myeloma patients. Genes located in the chromosomal aberration regions in our study, such as NAMPT, IVNS1ABP, IRF2BP2, PICALM, STAT1, STK17B, FBXL5, ACSL1, LAMP2, SAMSN1 and ATP8B4 might be potential prognostic markers and therapeutic targets in the treatment and management of multiple myeloma patients positive for BCL1/JH t(11;14 (q13;q32 translocation.

  1. Properties of ΣQ*, ΞQ* and ΩQ* heavy baryons in cold nuclear matter

    Science.gov (United States)

    Azizi, K.; Er, N.

    2018-02-01

    The in-medium properties of the heavy spin-3/2 ΣQ*, ΞQ* and ΩQ* baryons with Q being b or c quark are investigated. The shifts in some spectroscopic parameters of these particles due to the saturated cold nuclear matter are calculated. The variations of those parameters with respect to the changes in the density of the cold nuclear medium are studied, as well. It is observed that the parameters of ΣQ* baryons are considerably affected by the nuclear matter compared to the ΞQ* and ΩQ* particles that roughly do not see the medium. The results obtained may be used in analyses of the data to be provided by the in-medium experiments like PANDA.

  2. Low-Q Electrically Small Spherical Magnetic Dipole Antennas

    DEFF Research Database (Denmark)

    Kim, Oleksiy S.

    2010-01-01

    Three novel electrically small antenna configurations radiating a TE10 spherical mode corresponding to a magnetic dipole are presented and investigated: multiarm spherical helix (MSH) antenna, spherical split ring resonator (S-SRR) antenna, and spherical split ring (SSR) antenna. All three antennas...... are self-resonant, with the input resistance tuned to 50 ohms by an excitation curved dipole/monopole. A prototype of the SSR antenna has been fabricated and measured, yielding results that are consistent with the numerical simulations. Radiation quality factors (Q) of these electrically small antennas (in...

  3. Outcome of instrumented spinal fusion for chronic low back pain: review of 100 patients

    International Nuclear Information System (INIS)

    Qureshi, M.A; Pasha, I.F.; Malik, A.S.; Asad, A.; Aebi, M.

    2010-01-01

    Objective of this study was to evaluate the outcome of instrumented spinal fusion in selected patients with Chronic Low Back Pain (CLBP) in our setup. Consecutive first one hundred patients were selected from spine unit database that underwent instrumented spinal fusion for chronic low back pain lasting more than one year, due to degenerative disease of spine. Average age was 42 years. There were 62 males and 38 females. Diagnosis included; spinal stenosis (26%), failed disc surgery (22%), spondylolisthesis (19%), degenerative disc disease (17%), and instability (16%). Operations performed; Pedicle Screw Fixation (PSF) with Postero-lateral Fusion (PLF) in 3% patients. Trans Laminar Facet Screw (TLFS) with PLF in 24% patients. Anterior Lumbar Inter-body Fusion (ALIF) in 9% patients. Posterior Lumbar Inter-body Fusion (PLIF) in 40% patients and Trans-foraminal Lumbar Inter-body Fusion (TLIF) in 24% patients. Average follow up was for 30 months. 86% patients had full spinal fusion. 71% patients were fully satisfied with treatment, 28% were partially satisfied. Post-operatively, on average, visual analogue scale (VAS) showed 48 points significant improvement and Oswestry Disability Index (ODI) showed 53 points significant improvement. Instrumented Spinal Fusion is effective in our set up for relieving symptoms and improving functional outcome in selected patients with debilitating Chronic Low Back Pain due to degenerative disease of spine. Single fusion technique is not ideal for all types of patients and surgeon has to be versatile and trained in using different fusion techniques as the situation demands. (author)

  4. The Possible Heavy Tetraquarks $qQ\\bar q \\bar Q$, $qq\\bar Q \\bar Q$ and $qQ\\bar Q \\bar Q$

    OpenAIRE

    Cui, Ying; Chen, Xiao-Lin; Deng, Wei-Zhen; Zhu, Shi-Lin

    2006-01-01

    Assuming X(3872) is a $qc \\bar q \\bar c$ tetraquark and using its mass as input, we perform a schematic study of the masses of possible heavy tetraquarks using the color-magnetic interaction with the flavor symmetry breaking corrections.

  5. Electro-optic control of a PPLN-unpoled LiNbO3 boundary for low-voltage Q switching of an intracavity frequency-doubled Nd3+:YVO4 laser.

    Science.gov (United States)

    Torregrosa, A J; Maestre, H; Fernández-Pousa, C R; Pereda, J A; Capmany, J

    2009-08-01

    We present a simple technique to integrate an electro-optic Q switch in a periodically poled bulk lithium niobate crystal bounded by two unpoled (monodomain) regions. The technique exploits the high sensitivity to low applied electric fields of the total internal reflection condition in the periodic poled-unpoled boundary for the small grazing incidence angles associated with the diffraction of a focused Gaussian beam that propagates in the periodically poled region with its axis parallel to the boundary. When the arrangement is placed intracavity to a 1064 nm diode-pumped Nd(3+):YVO(4) laser, it performs simultaneously as a Q switch and as a second-harmonic generator, with Q switching starting at applied voltages as low as 1 V over a 500 microm thickness and with no additional optical elements.

  6. Hierarchy of the low-lying excitations for the (2+1-dimensional q=3 Potts model in the ordered phase

    Directory of Open Access Journals (Sweden)

    Yoshihiro Nishiyama

    2017-03-01

    Full Text Available The (2+1-dimensional q=3 Potts model was simulated with the exact diagonalization method. In the ordered phase, the elementary excitations (magnons are attractive, forming a series of bound states in the low-energy spectrum. We investigate the low-lying spectrum through a dynamical susceptibility, which is readily tractable with the exact diagonalization method via the continued-fraction expansion. As a result, we estimate the series of (scaled mass gaps, m2,3,4/m1 (m1: single-magnon mass, in proximity to the transition point.

  7. Acceptance Test Procedure for New Pumping Instrumentation and Control Skid Q

    International Nuclear Information System (INIS)

    KOCH, M.R.

    2000-01-01

    This Test Plan provides a test method to dedicate the leak detection relays used on the new Pumping Instrumentation and Control (PIC) skids. The new skids are fabricated on-site. The leak detection system is a safety class system per the Authorization Basis

  8. The very low angle detector for high-energy inelastic neutron scattering on the VESUVIO spectrometer

    International Nuclear Information System (INIS)

    Perelli Cippo, E.; Gorini, G.; Tardocchi, M.; Pietropaolo, A.; Andreani, C.; Senesi, R.; Rhodes, N.J.; Schooneveld, E.M.

    2008-01-01

    The Very Low Angle Detector (VLAD) bank has been installed on the VESUVIO spectrometer at the ISIS spallation neutron source. The new device allows for high-energy inelastic neutron scattering measurements, at energies above 1 eV, maintaining the wave vector transfer lower than 10A -1 . This opens a still unexplored region of the kinematical (q,ω) space, enabling new and challenging experimental investigations in condensed matter. This paper describes the main instrumental features of the VLAD device, including instrument design, detector response, and calibration procedure

  9. The very low angle detector for high-energy inelastic neutron scattering on the VESUVIO spectrometer

    Science.gov (United States)

    Perelli Cippo, E.; Gorini, G.; Tardocchi, M.; Pietropaolo, A.; Andreani, C.; Senesi, R.; Rhodes, N. J.; Schooneveld, E. M.

    2008-05-01

    The Very Low Angle Detector (VLAD) bank has been installed on the VESUVIO spectrometer at the ISIS spallation neutron source. The new device allows for high-energy inelastic neutron scattering measurements, at energies above 1 eV, maintaining the wave vector transfer lower than 10Å-1. This opens a still unexplored region of the kinematical (q, ω) space, enabling new and challenging experimental investigations in condensed matter. This paper describes the main instrumental features of the VLAD device, including instrument design, detector response, and calibration procedure.

  10. Discrete q-derivatives and symmetries of q-difference equations

    Energy Technology Data Exchange (ETDEWEB)

    Levi, D [Dipartimento di Fisica, Universita Roma Tre and INFN-Sezione di Roma Tre, Via della Vasca Navale 84, 00146 Rome (Italy); Negro, J [Departamento de FIsica Teorica, Universidad de Valladolid, E-47011, Valladolid (Spain); Olmo, M A del [Departamento de FIsica Teorica, Universidad de Valladolid, E-47011, Valladolid (Spain)

    2004-03-12

    In this paper we extend the umbral calculus, developed to deal with difference equations on uniform lattices, to q-difference equations. We show that many properties considered for shift invariant difference operators satisfying the umbral calculus can be implemented to the case of the q-difference operators. This q-umbral calculus can be used to provide solutions to linear q-difference equations and q-differential delay equations. To illustrate the method, we will apply the obtained results to the construction of symmetry solutions for the q-heat equation.

  11. Normative Data for Interpreting the BREAST-Q: Augmentation

    Science.gov (United States)

    Mundy, Lily R.; Homa, Karen; Klassen, Anne F.; Pusic, Andrea L.; Kerrigan, Carolyn L.

    2016-01-01

    Background The BREAST-Q is a rigorously developed, well-validated, patient-reported outcome (PRO) instrument with a module designed for evaluating breast augmentation outcomes. However, there are no published normative BREAST-Q scores, limiting interpretation. Methods Normative data were generated for the BREAST-Q Augmentation Module via the Army of Women (AOW), an online community of women (with and without breast cancer) engaged in breast-cancer related research. Members were recruited via email, with women 18 years or older without a history of breast cancer or breast surgery invited to participate. Descriptive statistics and a linear multivariate regression were performed. A separate analysis compared normative scores to findings from previously published BREAST-Q augmentation studies. Results The preoperative BREAST-Q Augmentation Module was completed by 1,211 women. Mean age was 54 ±24 years, mean body mass index (BMI) was 27 ±6, and 39% (n=467) had a bra cup size ≥D. Mean scores were Satisfaction with Breasts (54 ±19), Psychosocial Well-being (66 ±20), Sexual Well-being (49 ±20), and Physical Well-being (86 ±15). Women with a BMI of 30 or greater and bra cup size D or greater had lower scores. In comparison to AOW scores, published BREAST-Q augmentation scores were lower before and higher after surgery for all scales except Physical Well-being. Conclusions The AOW normative data represent breast-related satisfaction and well-being in woman not actively seeking breast augmentation. This data may be used as normative comparison values for those seeking and undergoing surgery as we did, demonstrating the value of breast augmentation in this patient population. PMID:28350657

  12. High field Q slope and the effect of low-temperature baking at 3 GHz

    Science.gov (United States)

    Ciovati, G.; Eremeev, G.; Hannon, F.

    2018-01-01

    A strong degradation of the unloaded quality factor with field, called high field Q slope, is commonly observed above Bp ≅100 mT in elliptical superconducting niobium cavities at 1.3 and 1.5 GHz. In the present experiments several 3 GHz niobium cavities were measured up to and above Bp ≅100 mT . The measurements show that a high field Q slope phenomenon limits the field reach at this frequency, that the high field Q slope onset field depends weakly on the frequency, and that the high field Q slope can be removed by the typical empirical solution of electropolishing followed by heating to 120°C for 48 hrs. In addition, one of the cavities reached a quench field of 174 mT and its field dependence of the quality factor was compared against global heating predicted by a thermal feedback model.

  13. A compact time-of-flight SANS instrument optimised for measurements of small sample volumes at the European Spallation Source

    Energy Technology Data Exchange (ETDEWEB)

    Kynde, Søren, E-mail: kynde@nbi.ku.dk [Niels Bohr Institute, University of Copenhagen (Denmark); Hewitt Klenø, Kaspar [Niels Bohr Institute, University of Copenhagen (Denmark); Nagy, Gergely [SINQ, Paul Scherrer Institute (Switzerland); Mortensen, Kell; Lefmann, Kim [Niels Bohr Institute, University of Copenhagen (Denmark); Kohlbrecher, Joachim, E-mail: Joachim.kohlbrecher@psi.ch [SINQ, Paul Scherrer Institute (Switzerland); Arleth, Lise, E-mail: arleth@nbi.ku.dk [Niels Bohr Institute, University of Copenhagen (Denmark)

    2014-11-11

    The high flux at European Spallation Source (ESS) will allow for performing experiments with relatively small beam-sizes while maintaining a high intensity of the incoming beam. The pulsed nature of the source makes the facility optimal for time-of-flight small-angle neutron scattering (ToF-SANS). We find that a relatively compact SANS instrument becomes the optimal choice in order to obtain the widest possible q-range in a single setting and the best possible exploitation of the neutrons in each pulse and hence obtaining the highest possible flux at the sample position. The instrument proposed in the present article is optimised for performing fast measurements of small scattering volumes, typically down to 2×2×2 mm{sup 3}, while covering a broad q-range from about 0.005 1/Å to 0.5 1/Å in a single instrument setting. This q-range corresponds to that available at a typical good BioSAXS instrument and is relevant for a wide set of biomacromolecular samples. A central advantage of covering the whole q-range in a single setting is that each sample has to be loaded only once. This makes it convenient to use the fully automated high-throughput flow-through sample changers commonly applied at modern synchrotron BioSAXS-facilities. The central drawback of choosing a very compact instrument is that the resolution in terms of δλ/λ obtained with the short wavelength neutrons becomes worse than what is usually the standard at state-of-the-art SANS instruments. Our McStas based simulations of the instrument performance for a set of characteristic biomacromolecular samples show that the resulting smearing effects still have relatively minor effects on the obtained data and can be compensated for in the data analysis. However, in cases where a better resolution is required in combination with the large simultaneous q-range characteristic of the instrument, we show that this can be obtained by inserting a set of choppers.

  14. Elastic J/{psi} production at low Q{sup 2} at HERA

    Energy Technology Data Exchange (ETDEWEB)

    Huber, Florian

    2010-05-15

    In this diploma thesis the elastic J/{psi} vector meson photoproduction (ep{yields}eJ/{psi}p) is studied in the decay channel J/{psi}{yields}e{sup +}e{sup -} with the H1 detector at the electron proton collider HERA. The data from the runs of the year 2007 with an integrated luminosity of 62.4 pb{sup -1} are used. In this time HERA operated with tree different proton energies E{sub p} called high (920 GeV), medium (575 GeV) and low (460 GeV) with integrated luminosities 45.5 (high), 5.96 (medium) and 10.9 pb{sup -1} (low). The kinematical region of vertical stroke t vertical stroke <1.2 GeV{sup 2}, where t is the four momentum transfer at the proton vertex, and Q{sub e}{sup 2}<1 GeV (photoproduction) is used. Further the range of the centre of mass energy in the photon proton rest frame, W{sub {gamma}}{sub p}, is restricted to 40 GeVlow). The differential cross section as a function of vertical stroke t vertical stroke is well described by an exponential, d{sigma} /d vertical stroke t vertical stroke {proportional_to} e{sup -b{sub 0}} {sup vertical} {sup stroke} {sup t} {sup vertical} {sup stroke}, which yields to b{sub 0}=4.4{+-}0.2(stat.). The cross section as a function of W{sub {gamma}}{sub p} is fitted by a power law, d{sigma}/dW{sub {gamma}}{sub p}{proportional_to}W{sup {delta}}{sub {gamma}}{sub p}, and gives {delta}=0.66{+-}0.07(stat.). (orig.)

  15. Functional differential equations for the q-Fourier transform of q-Gaussians

    International Nuclear Information System (INIS)

    Umarov, S; Queiros, S M Duarte

    2010-01-01

    In this paper the question 'is the q-Fourier transform of a q-Gaussian a q'-Gaussian (with some q') up to a constant factor?' is studied for the whole range of q in (- infty, 3). This question is connected with applicability of the q-Fourier transform in the study of limit processes in nonextensive statistical mechanics. Using the functional differential equation approach we prove that the answer is affirmative if and only if 1 ≤ q < 3, excluding two particular cases of q < 1, namely q=1/2 and q=2/3. Complementarily, we discuss some applications of the q-Fourier transform to nonlinear partial differential equations such as the porous medium equation.

  16. Functional differential equations for the q-Fourier transform of q-Gaussians

    Energy Technology Data Exchange (ETDEWEB)

    Umarov, S [Department of Mathematics, Tufts University, Medford, MA (United States); Queiros, S M Duarte, E-mail: sdqueiro@gmail.co [Unilever R and D Port Sunlight, Quarry Road East, Wirral, CH63 3JW (United Kingdom)

    2010-02-05

    In this paper the question 'is the q-Fourier transform of a q-Gaussian a q'-Gaussian (with some q') up to a constant factor?' is studied for the whole range of q in (- infty, 3). This question is connected with applicability of the q-Fourier transform in the study of limit processes in nonextensive statistical mechanics. Using the functional differential equation approach we prove that the answer is affirmative if and only if 1 <= q < 3, excluding two particular cases of q < 1, namely q=1/2 and q=2/3. Complementarily, we discuss some applications of the q-Fourier transform to nonlinear partial differential equations such as the porous medium equation.

  17. q-Deformed KP Hierarchy and q-Deformed Constrained KP Hierarchy

    OpenAIRE

    He, Jingsong; Li, Yinghua; Cheng, Yi

    2006-01-01

    Using the determinant representation of gauge transformation operator, we have shown that the general form of $au$ function of the $q$-KP hierarchy is a $q$-deformed generalized Wronskian, which includes the $q$-deformed Wronskian as a special case. On the basis of these, we study the $q$-deformed constrained KP ($q$-cKP) hierarchy, i.e. $l$-constraints of $q$-KP hierarchy. Similar to the ordinary constrained KP (cKP) hierarchy, a large class of solutions of $q$-cKP hierarchy can be represent...

  18. Planck 2013 results. II. The Low Frequency Instrument data processing

    DEFF Research Database (Denmark)

    Aghanim, N.; Armitage-Caplan, C.; Arnaud, M.

    2013-01-01

    We describe the data processing pipeline of the Planck Low Frequency Instrument (LFI) data processing centre (DPC) to create and characterize full-sky maps based on the first 15.5 months of operations at 30, 44, and 70 GHz. In particular, we discuss the various steps involved in reducing the data......) is employed to combine radiometric data and pointing information into sky maps, minimizing the variance of correlated noise. Noise covariance matrices, required to compute statistical uncertainties on LFI and Planck products, are also produced. Main beams are estimated down to the approximate to-20 dB level...

  19. The beam diagnostic instruments in Beijing radioactive ion-beam facilities isotope separator on-line

    International Nuclear Information System (INIS)

    Ma, Y.; Cui, B.; Ma, R.; Tang, B.; Chen, L.; Huang, Q.; Jiang, W.

    2014-01-01

    The beam diagnostic instruments for Beijing Radioactive Ion-beam Facilities Isotope Separator On-Line are introduced [B. Q. Cui, Z. H. Peng, Y. J. Ma, R. G. Ma, B. Tang, T. Zhang, and W. S. Jiang, Nucl. Instrum. Methods 266, 4113 (2008); T. J. Zhang, X. L. Guan, and B. Q. Cui, in Proceedings of APAC 2004, Gyeongju, Korea, 2004, http://www.jacow.org , p. 267]. For low intensity ion beam [30–300 keV/1 pA–10 μA], the beam profile monitor, the emittance measurement unit, and the analyzing slit will be installed. For the primary proton beam [100 MeV/200 μA], the beam profile scanner will be installed. For identification of the nuclide, a beam identification unit will be installed. The details of prototype of the beam diagnostic units and some experiment results will be described in this article

  20. Bose-Einstein correlation and Q-υKυ(Q) distribution

    International Nuclear Information System (INIS)

    Dai Qirun; Zhao Shusong

    1995-01-01

    Bose-Einstein correlation is one of the most useful means to study the source emitting hadrons. Based on the non-perturbative theory of quantum fields, we have proposed a kind of source distribution, i.e., the Q -υ K υ (Q) distribution, which is applied to calculate single inclusion distribution of P // , P perpecular , N, Y and the correlation with each other, i.e., Seagull effect. The results have a better approximation to the corresponding experimental data. The paper emphasizes the calculation of Bose-Einstein correlation for inclusive two particle based on the Q -υ K υ (Q) distribution. The fitted curves agree with experimental data, especially, in the small Q range. The Q -υ K υ (Q) distribution is a more advanced theory as compared with Gauss source and K-P source distribution

  1. Concurrent validation of two key health literacy instruments in a South Eastern European population.

    Science.gov (United States)

    Toçi, Ervin; Burazeri, Genc; Sørensen, Kristine; Kamberi, Haxhi; Brand, Helmut

    2015-06-01

    Public health practice has come to increasing recognition of health promotion and the central role of knowledge, attitude, beliefs and practices in achieving health promotion. Health literacy (HL) is an under-explored topic in South Eastern European countries. There are no HL reports from Albania to date. The aim of this study was to assess the concurrent validity of the European Health Literacy Survey Questionnaire (HLS-EU-Q) and the Test of Functional Health Literacy in Adults (TOFHLA) in a population-based sample of adults in Albania. A cross-sectional study was conducted in 2013 in Tirana, Albania, including 239 individuals aged ≥ 18 years (61% women; 87% response). A structured interviewer-administered questionnaire was applied twice (test and retest procedure after 2 weeks) including HLS-EU-Q and TOFHLA instruments. The internal consistency was high for both instruments (Cronbach's alpha for the test procedure was 0.92 for TOFHLA and 0.98 for HLS-EU-Q). Both tools exhibited a high stability over time (Spearman's rho: 0.88 for TOFHLA and 0.87 for HLS-EU). Mean values of both instruments were similar in men and women (mean score for TOFHLA: 76.0 vs. 76.5, P = 0.83; mean score for HLS-EU-Q: 32.2 vs. 32.6, P = 0.63). For both instruments, higher HL scores were significantly associated with younger age, higher educational and economic level and lower body mass index. Our study provides valuable novel evidence on concurrent validation of two major HL instruments in a South Eastern European population-based sample. Future studies should be conducted in order to confirm and expand our findings. © The Author 2014. Published by Oxford University Press on behalf of the European Public Health Association. All rights reserved.

  2. [Acute myeloid leukemia with monosomy 7 and inv(3)(q21q26.2) complicated with central diabetes insipidus].

    Science.gov (United States)

    Nanno, Satoru; Hagihara, Kiyoyuki; Sakabe, Manami; Okamura, Hiroshi; Inaba, Akiko; Nagata, Yuki; Nishimoto, Mitsutaka; Koh, Hideo; Nakao, Yoshitaka; Nakane, Takahiko; Nakamae, Hirohisa; Shimono, Taro; Hino, Masayuki

    2013-04-01

    A 20-year-old female presented with thirst, polyposia, and polyuria and was referred to our hospital because of leukocytosis and anemia. Bone marrow aspiration revealed 66.8% myeloperoxidase-positive blasts and trilineage myelodysplasia. The karyotype was 45, XX, inv(3)(q21q26.2), -7[19]. Therefore, a diagnosis of AML with inv(3)(q21q26.2) complicated by -7 was made. Moreover, hyposthenuria and a low anti-diuretic hormone (ADH) level were observed. Although cerebrospinal fluid analysis was normal, magnetic resonance imaging (MRI) revealed the absence of hyperintensity in the neurohypophysis in T1-weighted images. Therefore, she was also diagnosed with diabetes insipidus. After she was administered a desmopressin nasal spray, the volume of urine produced decreased. Following treatment with second induction therapy containing high-dose cytarabine for AML, she achieved complete remission in the bone marrow. Moreover, when the abnormality on MRI and the volume of urine were normalized, she discontinued desmopressin. Although diabetes insipidus is a rare complication of AML, the majority of AML patients who have diabetes insipidus have the abnormal karyotypes with inv(3)(q21q26.2)/t(3;3)(q21;q26.2) and monosomy 7. Further study is required to clarify the pathogenesis and develop a strategy for the treatment of this category of AML.

  3. Planck early results. III. First assessment of the Low Frequency Instrument in-flight performance

    DEFF Research Database (Denmark)

    Poutanen, T.; Lähteenmäki, A.; León-Tavares, J.

    2011-01-01

    The scientific performance of the Planck Low Frequency Instrument (LFI) after one year of in-orbit operation is presented. We describe the main optical parameters and discuss photometric calibration, white noise sensitivity, and noise properties. A preliminary evaluation of the impact of the main...

  4. Anti-C1q antibodies in systemic lupus erythematosus

    DEFF Research Database (Denmark)

    Orbai, A-M; Truedsson, L; Sturfelt, G

    2015-01-01

    OBJECTIVE: Anti-C1q has been associated with systemic lupus erythematosus (SLE) and lupus nephritis in previous studies. We studied anti-C1q specificity for SLE (vs rheumatic disease controls) and the association with SLE manifestations in an international multicenter study. METHODS: Information...... in combination with anti-dsDNA and low complement was the strongest serological association with renal involvement. These data support the usefulness of anti-C1q in SLE, especially in lupus nephritis....

  5. The very low angle detector for high-energy inelastic neutron scattering on the VESUVIO spectrometer

    Energy Technology Data Exchange (ETDEWEB)

    Perelli Cippo, E.; Gorini, G.; Tardocchi, M. [Dipartimento di Fisica ' G. Occhialini' , Universita degli Studi di Milano-Bicocca, Piazza della Scienza 3, 20126 Milano (Italy); Pietropaolo, A. [Dipartimento di Fisica ' G. Occhialini' , CNISM-Universita degli Studi di Milano-Bicocca, Piazza della Scienza 3, 20126 Milano (Italy); NAST Center - Nanoscienze-Nanotecnologie-Strumentazione, Universita degli Studi di Roma Tor Vergata, via della Ricerca Scientifica 1, 00133 Roma (Italy)], E-mail: antonino.pietropaolo@mib.infn.it; Andreani, C.; Senesi, R. [Dipartimento di Fisica and Centro NAST - Nanoscienze-Nanotecnologie-Strumentazione, Universita degli Studi di Roma Tor Vergata, via della Ricerca Scientifica 1, 00133 Roma (Italy); Rhodes, N.J.; Schooneveld, E.M. [ISIS Facility, Rutherford Appleton Laboratory, Chilton, Didcot, Oxfordshire 0QX OX11 (United Kingdom)

    2008-05-01

    The Very Low Angle Detector (VLAD) bank has been installed on the VESUVIO spectrometer at the ISIS spallation neutron source. The new device allows for high-energy inelastic neutron scattering measurements, at energies above 1 eV, maintaining the wave vector transfer lower than 10A{sup -1}. This opens a still unexplored region of the kinematical (q,{omega}) space, enabling new and challenging experimental investigations in condensed matter. This paper describes the main instrumental features of the VLAD device, including instrument design, detector response, and calibration procedure.

  6. Comparison of q anti qg and q anti qγ events in e+e- annihilation at PEP

    International Nuclear Information System (INIS)

    Hofmann, W.

    1986-07-01

    In comparing the particle flow in the event plane of three-jet (q anti qg) events and of radiative annihilation events (q anti qγ) for similar kinematic configurations, two PEP experiments find a significant decrease in particle density in the angular region opposite to the gluon jet in q anti qg events, relative to the particle density in the region opposite to the photon in q anti qγ events. The effect is predicted both by QCD and by phenomenological string models. 5 refs., 5 figs

  7. q-conformally covariant q-Minkowski space-time and invariant equations

    International Nuclear Information System (INIS)

    Dobrev, V.K.

    1997-09-01

    We present explicitly the covariant action of the q-conformal algebra on the q-Minkowski space we proposed earlier. We also present some q-conformally invariant equations, namely a hierarchy of q-Maxwell equations, and also a q-d'Alembert equation, proposed earlier by us, in a form different from the original . (author). 19 refs

  8. Lung ventilation-perfusion imbalance in pulmonary emphysema: assessment with automated V/Q quotient SPECT.

    Science.gov (United States)

    Suga, Kazuyoshi; Kawakami, Yasuhiko; Koike, Hiroaki; Iwanaga, Hideyuki; Tokuda, Osamu; Okada, Munemasa; Matsunaga, Naofumi

    2010-05-01

    Tc-99m-Technegas-MAA single photon emission computed tomography (SPECT)-derived ventilation (V)/perfusion (Q) quotient SPECT was used to assess lung V-Q imbalance in patients with pulmonary emphysema. V/Q quotient SPECT and V/Q profile were automatically built in 38 patients with pulmonary emphysema and 12 controls, and V/Q distribution and V/Q profile parameters were compared. V/Q distribution on V/Q quotient SPECT was correlated with low attenuation areas (LAA) on density-mask computed tomography (CT). Parameters of V/Q profile such as the median, standard deviation (SD), kurtosis and skewness were proposed to objectively evaluate the severity of lung V-Q imbalance. In contrast to uniform V/Q distribution on V/Q quotient SPECT and a sharp peak with symmetrical V/Q distribution on V/Q profile in controls, lung areas showing heterogeneously high or low V/Q and flattened peaks with broadened V/Q distribution were frequently seen in patients with emphysema, including lung areas with only slight LAA. V/Q distribution was also often asymmetric regardless of symmetric LAA. All the proposed parameters of V/Q profile in entire lungs of patients with emphysema showed large variations compared with controls; SD and kurtosis were significantly different from controls (P emphysema. SD and kurtosis of V/Q profile can be adequate parameters to assess the severity of lung V-Q imbalance causing gas-exchange impairment in patients with emphysema.

  9. Syntenic homology of human unique DNA sequences within chromossome regions 5q31, 10q22, 13q32-33 and 19q13.1 in the great apes

    Directory of Open Access Journals (Sweden)

    Rhea U. Vallente-Samonte

    2000-09-01

    Full Text Available Homologies between chromosome banding patterns and DNA sequences in the great apes and humans suggest an apparent common origin for these two lineages. The availability of DNA probes for specific regions of human chromosomes (5q31, 10q22, 13q32-33 and 19q13.1 led us to cross-hybridize these to chimpanzee (Pan troglodytes, PTR, gorilla (Gorilla gorilla, GGO and orangutan (Pongo pygmaeus, PPY chromosomes in a search for equivalent regions in the great apes. Positive hybridization signals to the chromosome 5q31-specific DNA probe were observed at HSA 5q31, PTR 4q31, GGO 4q31 and PPY 4q31, while fluorescent signals using the chromosome 10q22-specific DNA probe were noted at HSA 10q22, PTR 8q22, GGO 8q22 and PPY 7q22. The chromosome arms showing hybridization signals to the Quint-EssentialTM 13-specific DNA probe were identified as HSA 13q32-33, PTR 14q32-33, GGO 14q32-33 and PPY 14q32-33, while those presenting hybridization signals to the chromosome 19q13.1-specific DNA probe were identified as HSA 19q13.1, PTR 20q13, GGO 20q13 and PPY 20q13. All four probes presumably hybridized to homologous chromosomal locations in the apes, which suggests a homology of certain unique DNA sequences among hominoid species.Homologias entre os padrões de bandamento de cromossomos e seqüências de DNA em grandes macacos e humanos sugerem uma aparente origem comum para estas duas linhagens. A disponibilidade de sondas de DNA para regiões específicas de cromossomos humanos (5q31, 10q22, 13q32-33 e 19q13.1 nos levou a realizar hibridação cruzada com cromossomos de chimpanzé (Pan troglodytes, PTR, gorila (Gorilla gorilla, GGO e orangotango (Pongo pygmaeus, PPY em um pesquisa de regiões equivalentes em grandes macacos. Sinais positivos de hibridação para a sonda de DNA específica para o cromossomo 5q31 foram observados em HSA 5q31, PTR 4q31, GGO 4q31 e PPY 4q31, enquanto que sinais fluorescentes usando a sonda de DNA específica para o cromossomo 10q22 foram

  10. Fully On-chip High Q Inductors Based on Microtechnologies

    Directory of Open Access Journals (Sweden)

    Kriyang SHAH

    2010-04-01

    Full Text Available Wireless biosensor networks (WBSNs collect information about biological responses and process it using scattered battery-power sensor nodes. Such nodes demand ultra low-power consumption for longer operating time. Ultra Wide Band (UWB is a potential solution for WBSNs due to its advantage in low power consumption at reasonable data rate. However, such UBW technology requires high quality (Q factor passive components. This paper presents detailed analysis, design and optimization of physical parameters of silicon-on-sapphire (SOS and micro-electro-mechanical-systems (MEMS inductors for application in UWB transceivers. Results showed that the 1.5 nH SOS inductor achieved Q factor of 111 and MEMS inductor achieved Q factor of 45 at 4 GHz frequency. The voltage controlled oscillator (VCO designed with SOS inductor achieved more than 10 dBc/Hz reduction in phase noise and consumed half the power compared to VCO with MEMS inductor. Such low power VCO will improve battery life of a UWB wireless sensor node.

  11. Measurement of multijet events at low x{sub Bj} and low Q{sup 2} with the ZEUS detector at HERA

    Energy Technology Data Exchange (ETDEWEB)

    Gosau, T.

    2007-07-15

    In this thesis, cross sections of inclusive and differential di- and trijet production in deep inelastic electron-proton scattering at low Bjorken-x have been determined and compared to perturbative QCD calculations at next-to- leading order. The data were taken during the years 1998-2000 with the ZEUS detector at the HERA collider and had an integrated luminosity of 82 pb{sup -1}. The center-of-mass energy was {radical}(s)=318 GeV. The phase space was defined by 10{sup -4}Q{sup 2}<100 GeV{sup 2}, and 0.1Q{sup 2}, inelasticity of the photon, y, Bjorken-x, x{sub Bj}, transverse energy of the jets in the hadronic center-of-mass frame, E{sup jet}{sub T,HCM}, and the pseudorapidity of the jets in the laboratory frame, {eta}{sup jet}{sub LAB}. Multidifferential cross sections were measured as functions of x{sub Bj} and correlations of the jet momenta in the transverse plane. The 6m Tagger, which was reinstalled in 2003, was calibrated using the measurement of the photon energies by the Spectrometer. First measurements of the acceptance of the luminosity photon detectors where carried out. (orig.)

  12. A low power consumption and multi-function mini-printer for the portable nuclear instruments

    International Nuclear Information System (INIS)

    Jin Yuheng; Zhang Jiahong

    1994-01-01

    The authors presents a method of fitting a commercial printing calculator to the low power consumption and multi-function mini-printer. It can be employed as a compact data recorder and simple data processing device attached to the portable nuclear instruments, which are powered by dry batteries

  13. Exotic tetraquark states with the qq anti Q anti Q configuration

    Energy Technology Data Exchange (ETDEWEB)

    Luo, Si-Qiang; Chen, Kan; Liu, Xiang [Lanzhou University, School of Physical Science and Technology, Lanzhou (China); Lanzhou University and Institute of Modern Physics, CAS, Research Center for Hadron and CSR Physics, Lanzhou (China); Liu, Yan-Rui [Shandong University, School of Physics and Key Laboratory of Particle Physics and Particle Irradiation (MOE), Jinan (China); Zhu, Shi-Lin [Peking University, School of Physics and State Key Laboratory of Nuclear Physics and Technology, Beijing (China); Collaborative Innovation Center of Quantum Matter, Beijing (China); Peking University, Center for High Energy Physics, Beijing (China)

    2017-10-15

    In this work, we study systematically the mass splittings of the qq anti Q anti Q (q = u, d, s and Q = c, b) tetraquark states with the color-magnetic interaction by considering color mixing effects and estimate roughly their masses. We find that the color mixing effect is relatively important for the J{sup P} = 0{sup +} states and possible stable tetraquarks exist in the nn anti Q anti Q (n = u, d) and ns anti Q anti Q systems either with J = 0 or with J = 1. Possible decay patterns of the tetraquarks are briefly discussed. (orig.)

  14. Psychometric Evaluation of the Hypogonadism Impact of Symptoms Questionnaire Short Form (HIS-Q-SF).

    Science.gov (United States)

    Gelhorn, Heather L; Roberts, Laurie J; Khandelwal, Nikhil; Revicki, Dennis A; DeRogatis, Leonard R; Dobs, Adrian; Hepp, Zsolt; Miller, Michael G

    2017-08-01

    The Hypogonadism Impact of Symptoms Questionnaire Short Form (HIS-Q-SF) is a patient-reported outcome measurement designed to evaluate the symptoms of hypogonadism. The HIS-Q-SF is an abbreviated version including17 items from the original 28-item HIS-Q. To conduct item analyses and reduction, evaluate the psychometric properties of the HIS-Q-SF, and provide guidance on score interpretation. A 12-week observational longitudinal study of hypogonadal men was conducted as part of the original HIS-Q psychometric evaluation. Participants completed the original HIS-Q every 2 weeks. Blood samples were collected to evaluate testosterone levels. Participants completed the Aging Male's Symptoms Scale, the International Index of Erectile Function, the Short Form-12, and the PROMIS Sexual Activity, Satisfaction with Sex Life, Sleep Disturbance, and Applied Cognition Scales (baseline and weeks 6 and 12). Clinicians completed the Clinical Global Impression of Severity and Change scales and a clinical form. Item performance was evaluated using descriptive statistics and Rasch analyses. Reliability (internal consistency and test-retest), validity (concurrent and know groups), and responsiveness were assessed. One hundred seventy-seven men participated (mean age = 54.1 years, range = 23-83). Similar to the full HIS-Q, the final abbreviated HIS-Q-SF instrument includes five domains (sexual, energy, sleep, cognition, and mood) with two sexual subdomains (libido and sexual function). For key domains, test-retest reliability was very good, and construct validity was good for all domains. Known-groups validity was demonstrated for all domain scores, subdomain scores, and total score based on the Clinical Global Impression-Severity. All domains and subdomains were responsive to change based on patient-rated anchor questions. The HIS-Q-SF could be a useful tool in clinical practice, epidemiologic studies, and other academic research settings. Careful consideration was given to the

  15. Q-profile requirements for electro ITB formation

    Energy Technology Data Exchange (ETDEWEB)

    Goodman, T. P.; Coda, S.; Henderson, M. A.; Sauter, O.; Behn, R.; Bottino, A.; Fable, E.; Martynov, A.; Nikkola, P.; Zucca, C.

    2005-07-01

    The formation requirements of ITBs on numerous tokamaks have been correlated with either a power threshold, appearance of a low order rational surface near q{sub m}in or q{sub 9}5, weak or negative shear, etc. On TCV, electron ITBs (eITBs) can be formed during a gradual evolution from a centrally peaked to hollow current profile while all external actuators are held constant. The formation occurs rapidly (<{tau}{sub e}E) and locally and, according to ASTRA modeling, is correlated with the appearance of a local minimum in the q-profile. There is no clear evidence that the minimum in q appears at a low order rational. These eITBs are sustained by non-inductively driven current (ECCD and bootstrap current) while the current in the tokamak transformer is beld constant. Thus, they are not inherently transient but can exist for several current redistribution times; limited only by the pulse length of the gyrotrons. After the barrier is formed, the gransformer coil can be used as a counter (or co-) current source with negligible accompanying input power. The eITB performance can be enhanced (degraded) by altering solely the current or q-profile: when negative (positive) inductive current is driven, the on-axis current density decreases (increases) resulting in a stronger (weaker) reversed shear as both the ECCD and bootstrap currents are peaked off-axis. These experiments provide a unique realm of eITB formation and performance characteristics that can be used to isolate the physics criteria governing the eITB. (Author)

  16. Clinical, Molecular, and Prognostic Significance of WHO Type inv(3)(q21q26.2)/t(3;3)(q21;q26.2) and Various Other 3q Abnormalities in Acute Myeloid Leukemia

    NARCIS (Netherlands)

    Lugthart, Sanne; Groschel, Stefan; Beverloo, H. Berna; Kayser, Sabine; Valk, Peter J. M.; van Zelderen-Bhola, Shama Lydia; Ossenkoppele, Gert Jan; Vellenga, Edo; van den Berg-de Ruiter, Eva; Schanz, Urs; Verhoef, Gregor; Vandenberghe, Peter; Ferrant, Augustin; Kohne, Claus-Henning; Pfreundschuh, Michael; Horst, Heinz A.; Koller, Elisabeth; von Lilienfeld-Toal, Marie; Bentz, Martin; Ganser, Arnold; Schlegelberger, Brigitte; Jotterand, Martine; Krauter, Jurgen; Pabst, Thomas; Theobald, Matthias; Schlenk, Richard F.; Delwel, Ruud; Dohner, Konstanze; Lowenberg, Bob; Doehner, Hartmut

    2010-01-01

    Purpose Acute myeloid leukemia (AML) with inv(3)(q21q26.2)/t(3; 3)(q21; q26.2) inv(3)/t(3; 3)] is recognized as a distinctive entity in the WHO classification. Risk assignment and clinical and genetic characterization of AML with chromosome 3q abnormalities other than inv(3)/t(3; 3) remain largely

  17. Test-retest reliability of the eating disorder examination-questionnaire (EDE-Q) in a college sample

    OpenAIRE

    Rose, Jennifer S; Vaewsorn, Adin; Rosselli-Navarra, Francine; Wilson, G Terence; Weissman, Ruth Striegel

    2013-01-01

    Background The Eating Disorder Examination-Questionnaire (EDE-Q), a widely used self-report instrument, is often used for measuring change in eating disorder symptoms over the course of treatment. However, limited data exist about test-retest reliability, particularly for men. The current study evaluated EDE-Q 7-day test-retest reliability in male (n = 47) and female (n = 44) undergraduate students together and separately by gender. Results Internal consistency was consistently higher for wom...

  18. Effect of Coenzyme-Q10 on Doxorubicin-Induced Nephrotoxicity in Rats

    Directory of Open Access Journals (Sweden)

    Azza A. K. El-Sheikh

    2012-01-01

    Full Text Available Nephrotoxicity is one of the limiting factors for using doxorubicin (Dox as an anticancer chemotherapeutic. Here, we investigated possible protective effect of coenzyme-Q10 (CoQ10 on Dox-induced nephrotoxicity and the mechanisms involved. Two doses (10 and 100 mg/kg of CoQ10 were administered orally to rats for 8 days, in the presence or absence of nephrotoxicity induced by a single intraperitoneal injection of Dox (15 mg/kg at day 4 of the experiment. Our results showed that the low dose of CoQ10 succeeded in reversing Dox-induced nephrotoxicity to control levels (e.g., levels of blood urea nitrogen and serum creatinine, concentrations of renal reduced glutathione (GSH and malondialdehyde, catalase activity and caspase 3 expression, and renal histopathology. Alternatively, the high dose of CoQ10 showed no superior nephroprotection over the low dose, as there were no significant improvements in renal histopathology, catalase activity, or caspase 3 expression compared to the Dox-treated group. Interestingly, the high dose of CoQ10 alone significantly decreased renal GSH level as well as catalase activity and caused a mild induction of caspase 3 expression compared to control, probably due to a prooxidant effect at this dose of CoQ10. We conclude that CoQ10 protects from Dox-induced nephrotoxicity with a precaution to dosage adjustment.

  19. Compact, Passively Q-Switched Nd:YAG Laser for the MESSENGER Mission to the Planet Mercury

    Science.gov (United States)

    Krebs, Danny J.; Novo-Gradac, Anne-Marie; Li, Steven X.; Lindauer, Steven J.; Afzal, Robert S.; Yu, Antony

    2004-01-01

    A compact, passively Q-switched Nd:YAG laser has been developed for the Mercury Laser Altimeter (MLA) instrument which is an instrument on the MESSENGER mission to the planet Mercury. The laser achieves 5.4 percent efficiency with a near diffraction limited beam. It has passed all space flight environmental tests at system, instrument, and satellite integration. The laser design draws on a heritage of previous laser altimetry missions, specifically ISESAT and Mars Global Surveyor; but incorporates thermal management features unique to the requirements of an orbit of the planet Mercury.

  20. SKALA, a log-periodic array antenna for the SKA-low instrument: design, simulations, tests and system considerations

    Science.gov (United States)

    de Lera Acedo, E.; Razavi-Ghods, N.; Troop, N.; Drought, N.; Faulkner, A. J.

    2015-10-01

    The very demanding requirements of the SKA-low instrument call for a challenging antenna design capable of delivering excellent performance in radiation patterns, impedance matching, polarization purity, cost, longevity, etc. This paper is devoted to the development (design and test of the first prototypes) of an active ultra-wideband antenna element for the low-frequency instrument of the SKA radio telescope. The antenna element and differential low noise amplifier described here were originally designed to cover the former SKA-low band (70-450 MHz) but it is now aimed to cover the re-defined SKA-low band (50-350 MHz) and furthermore the antenna is capable of performing up to 650 MHz with the current design. The design is focused on maximum sensitivity in a wide field of view (+/- 45° from zenith) and low cross-polarization ratios. Furthermore, the size and cost of the element has to be kept to a minimum as millions of these antennas will need to be deployed for the full SKA in very compact configurations. The primary focus of this paper is therefore to discuss various design implications for the SKA-low telescope.

  1. Instrumentation for low noise nanopore-based ionic current recording under laser illumination

    Science.gov (United States)

    Roelen, Zachary; Bustamante, José A.; Carlsen, Autumn; Baker-Murray, Aidan; Tabard-Cossa, Vincent

    2018-01-01

    We describe a nanopore-based optofluidic instrument capable of performing low-noise ionic current recordings of individual biomolecules under laser illumination. In such systems, simultaneous optical measurements generally introduce significant parasitic noise in the electrical signal, which can severely reduce the instrument sensitivity, critically hindering the monitoring of single-molecule events in the ionic current traces. Here, we present design rules and describe simple adjustments to the experimental setup to mitigate the different noise sources encountered when integrating optical components to an electrical nanopore system. In particular, we address the contributions to the electrical noise spectra from illuminating the nanopore during ionic current recording and mitigate those effects through control of the illumination source and the use of a PDMS layer on the SiNx membrane. We demonstrate the effectiveness of our noise minimization strategies by showing the detection of DNA translocation events during membrane illumination with a signal-to-noise ratio of ˜10 at 10 kHz bandwidth. The instrumental guidelines for noise minimization that we report are applicable to a wide range of nanopore-based optofluidic systems and offer the possibility of enhancing the quality of synchronous optical and electrical signals obtained during single-molecule nanopore-based analysis.

  2. Role of low order rational q values in the ITB-events in JT-60U plasmas

    International Nuclear Information System (INIS)

    Neudatchin, S.V.

    2002-01-01

    The formation of internal transport barriers (ITBs) near q=2,3 surfaces in normal (NrS) or optimized shear discharges of JT-60U and JET is well known. In reverse shear (RS) JT-60U plasmas, the role of q minimum (q min ) equal to 3.5, 3, 2.5, 2 is not obvious for ITB evolution. ITB-events (non-local confinement bifurcations inside and around ITB in a ms timescale) are found in various JT-60U NrS and RS plasmas. (a) Under sufficient power, ITB-events are seen at rational and not rational values of q min . The space-time evolution of Te and Ti is similar. The temporal creation of stronger ITB in H-mode (after periodical improvements and degradations via ITB-events with 8 ms period) under passing of q min = 3 is presented (P nbi = 8 MW, 1.5 MA / 3.7 T). (b) Under smaller power, the influence of some rational q min is seen clearly for ITB-events on T e . In 1.3MA/3.7T shot with very weak RS (Pnbi = 4 MW), abrupt rise of T e is seen at q min 3:5, while more cases of T i rise are observed. (c) The possible role of MHD-activity as ITB-events trigger (ms time scale correlation in some NrS and RS cases) is under investigation. (author)

  3. q-Bernoulli numbers and q-Bernoulli polynomials revisited

    Directory of Open Access Journals (Sweden)

    Kim Taekyun

    2011-01-01

    Full Text Available Abstract This paper performs a further investigation on the q-Bernoulli numbers and q-Bernoulli polynomials given by Acikgöz et al. (Adv Differ Equ, Article ID 951764, 9, 2010, some incorrect properties are revised. It is point out that the generating function for the q-Bernoulli numbers and polynomials is unreasonable. By using the theorem of Kim (Kyushu J Math 48, 73-86, 1994 (see Equation 9, some new generating functions for the q-Bernoulli numbers and polynomials are shown. Mathematics Subject Classification (2000 11B68, 11S40, 11S80

  4. A Boy with an LCR3/4-Flanked 10q22.3q23.2 Microdeletion and Uncommon Phenotypic Features

    Science.gov (United States)

    Petrova, E.; Neuner, C.; Haaf, T.; Schmid, M.; Wirbelauer, J.; Jurkutat, A.; Wermke, K.; Nanda, I.; Kunstmann, E.

    2014-01-01

    The recurrent 10q22.3q23.2 deletion with breakpoints within low copy repeats 3 and 4 is a rare genomic disorder, reported in only 13 patients to date. The phenotype is rather uncharacteristic, which makes a clinical diagnosis difficult. A phenotypic feature described in almost all patients is a delay in speech development, albeit systematic studies are still pending. In this study, we report on a boy with an LCR3/4-flanked 10q22.3q23.2 deletion exhibiting an age-appropriate language development evaluated by a standardized test at an age of 2 years and 3 months. The boy was born with a cleft palate – a feature not present in any of the patients described before. Previously reported cases are reviewed, and the role of the BMPR1A gene is discussed. The phenotype of patients with an LCR3/4-flanked 10q22.3q23.2 deletion can be rather variable, so counseling the families regarding the prognosis of an affected child should be done with caution. Long-term studies of affected children are needed to delineate the natural history of this rare disorder. PMID:24550761

  5. Thales: an instrument to measure the low field magnetophoretic mobility of microscopic objects

    International Nuclear Information System (INIS)

    Hackett, S L; St Pierre, T G

    2005-01-01

    An instrument, Thales, was designed and constructed to measure the induce motion of magnetic microspheres in a low magnetic field strength environment. Results show that Thales can be used to precisely measure the speed of microspheres (± 0.08 μm.s -1 ). We evaluated the motion of magnetic microspheres induced by an inhomogeneous magnetic field, and developed models for the microsphere magnetophoretic mobility, a parameter determining the speed attained by the microsphere in a given static low strength magnetic field environment. The data suggested that the magnetic material was located at the surfaces of the microspheres rather than being distributed evenly through the microspheres. With suitable calibration microspheres, Thales will be capable of directly measuring the low field magnetophoretic mobility of microscopic objects

  6. High Precision Linear And Circular Polarimetry. Sources With Stable Stokes Q,U & V In The Ghz Regime

    Science.gov (United States)

    Myserlis, Ioannis; Angelakis, E.; Zensus, J. A.

    2017-10-01

    We present a novel data analysis pipeline for the reconstruction of the linear and circular polarization parameters of radio sources. It includes several correction steps to minimize the effect of instrumental polarization, allowing the detection of linear and circular polarization degrees as low as 0.3 %. The instrumental linear polarization is corrected across the whole telescope beam and significant Stokes Q and U can be recovered even when the recorded signals are severely corrupted. The instrumental circular polarization is corrected with two independent techniques which yield consistent Stokes V results. The accuracy we reach is of the order of 0.1-0.2 % for the polarization degree and 1\\u00ba for the angle. We used it to recover the polarization of around 150 active galactic nuclei that were monitored monthly between 2010.6 and 2016.3 with the Effelsberg 100-m telescope. We identified sources with stable polarization parameters that can be used as polarization standards. Five sources have stable linear polarization; three are linearly unpolarized; eight have stable polarization angle; and 11 sources have stable circular polarization, four of which with non-zero Stokes V.

  7. Chromosomal amplifications, 3q gain and deletions of 2q33-q37 are the frequent genetic changes in cervical carcinoma

    International Nuclear Information System (INIS)

    Rao, Pulivarthi H; Murty, Vundavalli VVS; Arias-Pulido, Hugo; Lu, Xin-Yan; Harris, Charles P; Vargas, Hernan; Zhang, Fang F; Narayan, Gopeshwar; Schneider, Achim; Terry, Mary Beth

    2004-01-01

    Carcinoma of uterine cervix is the second most common cancers among women worldwide. Combined radiation and chemotherapy is the choice of treatment for advanced stages of the disease. The prognosis is poor, with a five-year survival rate ranging from about 20–65%, depending on stage of the disease. Therefore, genetic characterization is essential for understanding the biology and clinical heterogeneity in cervical cancer (CC). We used a genome-wide screening method – comparative genomic hybridization (CGH) to identify DNA copy number changes in 77 patients with cervical cancer. We applied categorical and survival analyses to analyze whether chromosomal changes were related to clinico-pathologic characteristics and patients survival. The CGH analysis revealed a loss of 2q33-q37 (57.1%), gain of 3q (54.5%) and chromosomal amplifications (20.77%) as frequent genetic changes. A total of 15 amplified chromosomal sites were detected in 16 cases that include 1p31, 2q32, 7q22, 8q21.2-q24, 9p22, 10q21, 10q24, 11q13, 11q21, 12q15, 14q12, 17p11.2, 17q22, 18p11.2, and 19q13.1. Recurrent amplified sites were noted at 11q13, 11q21, and 19q13.1. The genomic alterations were further evaluated for prognostic significance in CC patients, and we did not find any correlation with a number of clinical or histological parameters. The tumors harboring HPV18 exhibited higher genomic instability compared to tumors with HPV 16. This study demonstrated that 2q33-q37 deletions, 3q gains and chromosomal amplifications as characteristic changes in invasive CC. These genetic alterations will aid in the identification of novel tumor suppressor gene(s) at 2q33-q37 and oncogenes at amplified chromosomal sites. Molecular characterization of these chromosomal changes utilizing the current genomic technologies will provide new insights into the biology and clinical behavior of CC

  8. High Precision Measurement of the Proton Elastic Form Factor Ratio at Low Q2

    Energy Technology Data Exchange (ETDEWEB)

    Zhan, Xiaohui [Massachusetts Inst. of Technology (MIT), Cambridge, MA (United States)

    2010-01-01

    Experiment E08-007 measured the proton elastic form factor ratio μpGE/GM in the range of Q2 = 0.3-0.7(GeV/c)2 by recoil polarimetry. Data were taken in 2008 at the Thomas Jefferson National Accelerator Facility in Virginia, USA. A 1.2 GeV polarized electron beam was scattered off a cryogenic hydrogen target. The recoil proton was detected in the left HRS in coincidence with the elasticly scattered electrons tagged by the BigBite spectrometer. The proton polarization was measured by the focal plane polarimeter (FPP). In this low Q2 region, previous measurement from Jefferson Lab Hall A (LEDEX) along with various fits and calculations indicate substantial deviations of the ratio from unity. For this new measurement, the proposed statistical uncertainty (< 1%) was achieved. These new results are a few percent lower than expected from previous world data and fits, which indicate a smaller GEp at this region. Beyond the intrinsic interest in nucleon structure, the new results also have implications in determining the proton Zemach radius and the strangeness form factors from parity violation experiments.

  9. PLANETARY CANDIDATES OBSERVED BY KEPLER IV: PLANET SAMPLE FROM Q1-Q8 (22 MONTHS)

    International Nuclear Information System (INIS)

    Burke, Christopher J.; Mullally, F.; Rowe, Jason F.; Thompson, Susan E.; Coughlin, Jeffrey L.; Caldwell, Douglas A.; Jenkins, Jon M.; Bryson, Stephen T.; Haas, Michael R.; Batalha, Natalie M.; Borucki, William J.; Christiansen, Jessie L.; Ciardi, David R.; Still, Martin; Barclay, Thomas; Chaplin, William J.; Clarke, Bruce D.; Cochran, William D.; Demory, Brice-Olivier; Esquerdo, Gilbert A.

    2014-01-01

    We provide updates to the Kepler planet candidate sample based upon nearly two years of high-precision photometry (i.e., Q1-Q8). From an initial list of nearly 13,400 threshold crossing events, 480 new host stars are identified from their flux time series as consistent with hosting transiting planets. Potential transit signals are subjected to further analysis using the pixel-level data, which allows background eclipsing binaries to be identified through small image position shifts during transit. We also re-evaluate Kepler Objects of Interest (KOIs) 1-1609, which were identified early in the mission, using substantially more data to test for background false positives and to find additional multiple systems. Combining the new and previous KOI samples, we provide updated parameters for 2738 Kepler planet candidates distributed across 2017 host stars. From the combined Kepler planet candidates, 472 are new from the Q1-Q8 data examined in this study. The new Kepler planet candidates represent ∼40% of the sample with R P ∼ 1 R ⊕ and represent ∼40% of the low equilibrium temperature (T eq < 300 K) sample. We review the known biases in the current sample of Kepler planet candidates relevant to evaluating planet population statistics with the current Kepler planet candidate sample

  10. Triply heavy tetraquark states with the $QQ\\bar{Q}\\bar{q}$ configuration

    OpenAIRE

    Chen, Kan; Liu, Xiang; Wu, Jing; Liu, Yan-Rui; Zhu, Shi-Lin

    2016-01-01

    In the framework of the color-magnetic interaction, we systematically investigate the mass splittings of the $QQ\\bar{Q}\\bar{q}$ tetraquark states and estimated their rough masses in this work. These systems include the explicitly exotic states $cc\\bar{b}\\bar{q}$ and $bb\\bar{c}\\bar{q}$ and the hidden exotic states $cc\\bar{c}\\bar{q}$, $cb\\bar{b}\\bar{q}$, $bc\\bar{c}\\bar{q}$, and $bb\\bar{b}\\bar{q}$. If a state around the estimated mass region could be observed, its nature as a genuine tetraquark ...

  11. High field Q slope and the effect of low-temperature baking at 3 GHz

    Directory of Open Access Journals (Sweden)

    G. Ciovati

    2018-01-01

    Full Text Available A strong degradation of the unloaded quality factor with field, called high field Q slope, is commonly observed above B_{p}≅100  mT in elliptical superconducting niobium cavities at 1.3 and 1.5 GHz. In the present experiments several 3 GHz niobium cavities were measured up to and above B_{p}≅100  mT. The measurements show that a high field Q slope phenomenon limits the field reach at this frequency, that the high field Q slope onset field depends weakly on the frequency, and that the high field Q slope can be removed by the typical empirical solution of electropolishing followed by heating to 120°C for 48 hrs. In addition, one of the cavities reached a quench field of 174 mT and its field dependence of the quality factor was compared against global heating predicted by a thermal feedback model.

  12. Partial monosomy 8q and partial trisomy 9q due to the maternal translocation t(8;9(q24.3;q34.1)

    DEFF Research Database (Denmark)

    Tos, T; Alp, M Y; Eker, H K

    2014-01-01

    Partial trisomy 9q34-qter and partial monosomy 8q24.3-qter are very rare chromosomal abnormalities. Characteristic features of partial trisomy 9q34-qter are hypotonia, developmental delay, mild intellectual disability, dolichocephaly, distinct facial phenotype, long and thin fingers, and cardiac...

  13. Lung ventilation-perfusion imbalance in pulmonary emphysema. Assessment with automated V/Q quotient SPECT

    International Nuclear Information System (INIS)

    Suga, Kazuyoshi; Kawakami, Yasuhiko; Koike, Hiroaki; Iwanaga, Hideyuki; Tokuda, Osamu; Okada, Munemasa; Matsunaga, Naofumi

    2010-01-01

    Tc-99m-Technegas-macro-aggregated albumin (MAA) single photon emission computed tomography (SPECT)-derived ventilation (V)/perfusion (Q) quotient SPECT was used to assess lung V-Q imbalance in patients with pulmonary emphysema. V/Q quotient SPECT and V/Q profile were automatically built in 38 patients with pulmonary emphysema and 12 controls, and V/Q distribution and V/Q profile parameters were compared. V/Q distribution on V/Q quotient SPECT was correlated with low attenuation areas (LAA) on density-mask computed tomography (CT). Parameters of V/Q profile such as the median, standard deviation (SD), kurtosis and skewness were proposed to objectively evaluate the severity of lung V-Q imbalance. In contrast to uniform V/Q distribution on V/Q quotient SPECT and a sharp peak with symmetrical V/Q distribution on V/Q profile in controls, lung areas showing heterogeneously high or low V/Q and flattened peaks with broadened V/Q distribution were frequently seen in patients with emphysema, including lung areas with only slight LAA. V/Q distribution was also often asymmetric regardless of symmetric LAA. All the proposed parameters of V/Q profile in entire lungs of patients with emphysema showed large variations compared with controls; SD and kurtosis were significantly different from controls (P<0.0001 and P<0.001, respectively), and a significant correlation was found between SD and A-aDO2 (P<0.0001). V/Q quotient SPECT appears to be more sensitive to detect emphysematous lungs compared with morphologic CT in patients with emphysema. SD and kurtosis of V/Q profile can be adequate parameters to assess the severity of lung V-Q imbalance causing gas-exchange impairment in patients with emphysema. (author)

  14. Q-phonons, Q-invariants, and company

    International Nuclear Information System (INIS)

    Brentano, P. von; Gade, A.; Pietralla, N.; Werner, V.

    2002-01-01

    The paper discusses the concept of Q-phonons and its connection to the concept of Q-invariants and the shape parameters of nuclei. It will also discuss some useful relations between Q-invariants and observables. These relations allow one to determine crucial nuclear observables such as the square of the quadrupole moment of the first 2+ state from lifetime data of the gamma- and ground band which may have applications, in future measurements with rare isotopes beams. These concepts are discussed for the Barium, Xenon and Cerium nuclei with mass numbers around A = 130, because some of these concepts were either introduced or at least heavily used in the discussion of the nuclear structure of these nuclei

  15. Asymptotics of diagonal elements of projection matrices under many instruments/regressors

    Czech Academy of Sciences Publication Activity Database

    Anatolyev, Stanislav; Yaskov, P.

    2017-01-01

    Roč. 33, č. 3 (2017), s. 717-738 ISSN 0266-4666 Institutional support: Progres-Q24 Keywords : instrumental variable estimation * inference * models Subject RIV: AH - Economics OBOR OECD: Applied Economics, Econometrics Impact factor: 1.011, year: 2016

  16. Instrumental analysis by gamma spectrometry of low level caesium-137 in marine samples

    International Nuclear Information System (INIS)

    Figueira, R.C.L.; Silva, L.R.N.; Figueiredo, A.M.G.; Cunha, I.I.L.

    1998-01-01

    An instrumental method for the analysis of low levels of 137 Cs in marine samples consists in calibrating the detector, determining the counting efficiency of the detector, accumulative counts of background and sample and smoothing the 661.6 keV photopeak. The methodology was applied to reference samples containing low levels of 137 Cs, showing a good accuracy. It was further applied to sediment samples from the southern coast of Brazil. The levels obtained ranged between 1.0 and 1.8 Bq.kg -1 , and the lower limit of detection and minimum detectable concentration values were 10 mBq and 0.28 Bq.kg -1 , respectively. (author)

  17. q-deformed Poincare algebra

    International Nuclear Information System (INIS)

    Ogievetsky, O.; Schmidke, W.B.; Wess, J.; Muenchen Univ.; Zumino, B.; Lawrence Berkeley Lab., CA

    1992-01-01

    The q-differential calculus for the q-Minkowski space is developed. The algebra of the q-derivatives with the q-Lorentz generators is found giving the q-deformation of the Poincare algebra. The reality structure of the q-Poincare algebra is given. The reality structure of the q-differentials is also found. The real Laplaacian is constructed. Finally the comultiplication, counit and antipode for the q-Poincare algebra are obtained making it a Hopf algebra. (orig.)

  18. Fermi-Dirac correlation and Q-νKν(Q) distribution

    International Nuclear Information System (INIS)

    Dai Qirun; Li Jimei; Ma Zhanqing; Zhao Shusong

    1996-01-01

    The Fermi-Dirac correlation of identical protons is studied. Based on the non-perturbative theory of quantum fields, we put forward a kind of source distribution--the Q -ν K ν (Q) distribution. The Fermi-Dirac correlation of (p +- -p +- )-pairs is calculated from this distribution. The fitted curves agree with experimental data. The Q -ν K ν (Q) distribution has more advantages than the Gauss Source distribution. The radii of the source emitting hadrons and the anomalous dimensions of the Fermi field are calculated from the Fermi-Dirac correlation of identical protons

  19. Ultra-low noise TES bolometer arrays for SAFARI instrument on SPICA

    Science.gov (United States)

    Khosropanah, P.; Suzuki, T.; Ridder, M. L.; Hijmering, R. A.; Akamatsu, H.; Gottardi, L.; van der Kuur, J.; Gao, J. R.; Jackson, B. D.

    2016-07-01

    SRON is developing ultra-low noise Transition Edge Sensors (TESs) based on a superconducting Ti/Au bilayer on a suspended SiN island with SiN legs for the SAFARI instrument aboard the SPICA mission. We successfully fabricated TESs with very narrow (0.5-0.7 μm) and thin (0.25 μm) SiN legs on different sizes of SiN islands using deep reactiveion etching process. The pixel size is 840x840 μm2 and there are variety of designs with and without optical absorbers. For TESs without absorbers, we measured electrical NEPs as low as <1x10-19 W/√Hz with response time of 0.3 ms and reached the phonon noise limit. Using TESs with absorbers, we quantified the darkness of our setup and confirmed a photon noise level of 2x10-19 W/√Hz.

  20. Open-Source 3-D Platform for Low-Cost Scientific Instrument Ecosystem.

    Science.gov (United States)

    Zhang, C; Wijnen, B; Pearce, J M

    2016-08-01

    The combination of open-source software and hardware provides technically feasible methods to create low-cost, highly customized scientific research equipment. Open-source 3-D printers have proven useful for fabricating scientific tools. Here the capabilities of an open-source 3-D printer are expanded to become a highly flexible scientific platform. An automated low-cost 3-D motion control platform is presented that has the capacity to perform scientific applications, including (1) 3-D printing of scientific hardware; (2) laboratory auto-stirring, measuring, and probing; (3) automated fluid handling; and (4) shaking and mixing. The open-source 3-D platform not only facilities routine research while radically reducing the cost, but also inspires the creation of a diverse array of custom instruments that can be shared and replicated digitally throughout the world to drive down the cost of research and education further. © 2016 Society for Laboratory Automation and Screening.

  1. C anti c q anti q states

    Energy Technology Data Exchange (ETDEWEB)

    Chao, K T [Oxford Univ. (UK). Dept. of Theoretical Physics; Science Research Council, Chilton (UK). Rutherford and Appleton Labs.)

    1980-07-01

    Taking account of the colour magnetic and electric forces, we discuss the spectroscopy of various types of c anti c q anti q states. Their decay, hadronic production, production in e/sup +/e/sup -/ annihilation as well as photoproduction are also studied.

  2. The Q* Index: A Useful Global Measure of Dementia Screening Test Accuracy

    Directory of Open Access Journals (Sweden)

    A.J. Larner

    2015-06-01

    Full Text Available Background/Aims: Single, global or unitary, indicators of test diagnostic performance have intuitive appeal for clinicians. The Q* index, the point in receiver operating characteristic (ROC curve space closest to the ideal top left-hand corner and where test sensitivity and specificity are equal, is one such measure. Methods: Datasets from four pragmatic accuracy studies which examined the Mini-Mental State Examination, Addenbrooke's Cognitive Examination-Revised, Montreal Cognitive Assessment, Test Your Memory test, and Mini-Addenbrooke's Cognitive Examination were examined to calculate and compare the Q* index, the maximal correct classification accuracy, and the maximal Youden index, as well as the sensitivity and specificity at these cutoffs. Results: Tests ranked similarly for the Q* index and the area under the ROC curve (AUC ROC. The Q* index cutoff was more sensitive (and less specific than the maximal correct classification accuracy cutoff, and less sensitive (and more specific than the maximal Youden index cutoff. Conclusion: The Q* index may be a useful global parameter summarising the test accuracy of cognitive screening instruments, facilitating comparison between tests, and defining a possible test cutoff value. As the point of equal sensitivity and specificity, its use may be more intuitive and appealing for clinicians than AUC ROC.

  3. Triply heavy tetraquark states with the QQ anti Q anti q configuration

    Energy Technology Data Exchange (ETDEWEB)

    Chen, Kan; Liu, Xiang [Lanzhou University, School of Physical Science and Technology, Lanzhou (China); Lanzhou University and Institute of Modern Physics of CAS, Research Center for Hadron and CSR Physics, Lanzhou (China); Liu, Yan-Rui; Wu, Jing [Shandong University, School of Physics and Key Laboratory of Particle Physics and Particle Irradiation (MOE), Jinan (China); Zhu, Shi-Lin [Peking University, School of Physics and State Key Laboratory of Nuclear Physics and Technology, Beijing (China); Collaborative Innovation Center of Quantum Matter, Beijing (China); Peking University, Center of High Energy Physics, Beijing (China)

    2017-01-15

    In the framework of the color-magnetic interaction, we systematically investigate the mass splittings of the QQ anti Q anti q tetraquark states and estimate their rough masses in this work. These systems include the explicitly exotic states cc anti b anti q and bb anti c anti q and the hidden exotic states cc anti c anti q, cb anti b anti q, bc anti c anti q, and bb anti b anti q. If a state around the estimated mass region can be observed, its nature as a genuine tetraquark is favored. The strong decay patterns shown here will be helpful to the experimental search for these exotic states. (orig.)

  4. Q QIAO

    Indian Academy of Sciences (India)

    Home; Journals; Bulletin of Materials Science. Q QIAO. Articles written in Bulletin of Materials Science. Volume 39 Issue 2 April 2016 pp 519-523. Effect of temperature on structure and corrosion resistance for electroless NiWP coating · M Q YU Q QIAO F YOU C L LI Y ZHAO Z Z XIAO H L LUO Z F XU KAZUHIRO MATSUGI ...

  5. Symmetric q-Bessel functions

    Directory of Open Access Journals (Sweden)

    Giuseppe Dattoli

    1996-05-01

    Full Text Available q analog of bessel functions, symmetric under the interchange of q and q^ −1 are introduced. The definition is based on the generating function realized as product of symmetric q-exponential functions with appropriate arguments. Symmetric q-Bessel function are shown to satisfy various identities as well as second-order q-differential equations, which in the limit q → 1 reproduce those obeyed by the usual cylindrical Bessel functions. A brief discussion on the possible algebraic setting for symmetric q-Bessel functions is also provided.

  6. Supermassive dark-matter Q-balls in galactic centers?

    Energy Technology Data Exchange (ETDEWEB)

    Troitsky, Sergey [Institute for Nuclear Research of the Russian Academy of Sciences,60th October Anniversary Prospect 7a, Moscow 117312 (Russian Federation); Moscow Institute for Physics and Technology,Institutskii per. 9, 141700, Dolgoprudny, Moscow Region (Russian Federation)

    2016-11-11

    Though widely accepted, it is not proven that supermassive compact objects (SMCOs) residing in galactic centers are black holes. In particular, the Milky Way’s SMCO can be a giant nontopological soliton, Q-ball, made of a scalar field: this fits perfectly all observational data. Similar but tiny Q-balls produced in the early Universe may constitute, partly or fully, the dark matter. This picture explains in a natural way, why our SMCO has very low accretion rate and why the observed angular size of the corresponding radio source is much smaller than expected. Interactions between dark-matter Q-balls may explain how SMCOs were seeded in galaxies and resolve well-known problems of standard (non-interacting) dark matter.

  7. q-deformed Weinberg-Salam model and q-deformed Maxwell equations

    International Nuclear Information System (INIS)

    Alavi, S.A.; Sarbishaei, M.; Mokhtari, A.

    2000-01-01

    We study the q-deformation of the gauge part of the Weinberg-Salam model and show that the q-deformed theory involves new interactions. We then obtain q-deformed Maxwell equations from which magnetic monopoles appear naturally. (author)

  8. Panels with low-Q-factor resonators with theoretically infinite sound-proofing ability at a single frequency

    Science.gov (United States)

    Lazarev, L. A.

    2015-07-01

    An infinite panel with two types of resonators regularly installed on it is theoretically considered. Each resonator is an air-filled cavity hermetically closed by a plate, which executes piston vibrations. The plate and air inside the cavity play the roles of mass and elasticity, respectively. Every other resonator is reversed. At a certain ratio between the parameters of the resonators at the tuning frequency of the entire system, the acoustic-pressure force that directly affects the panel can be fully compensated by the action forces of the resonators. In this case, the sound-proofing ability (transmission loss) tends to infinity. The presented calculations show that a complete transmission-loss effect can be achieved even with low- Q resonators.

  9. Validation of low-cost ozone measurement instruments suitable for use in an air-quality monitoring network

    International Nuclear Information System (INIS)

    Williams, David E; Henshaw, Geoff S; Bart, Mark; Laing, Greer; Wagner, John; Naisbitt, Simon; Salmond, Jennifer A

    2013-01-01

    This paper presents a novel low-cost instrument that uses a sensor based on conductivity changes of heated tungstic oxide, which is capable of accurately measuring ambient concentrations of ozone. A combination of temperature steps and air flow-rate steps is used to continually reset and re-zero the sensor. A two-stage calibration procedure is presented, in which a nonlinear transformation converts sensor resistance to a signal linear in ozone concentration, then a linear correlation is used to align the calibration with a reference instrument. The required calibration functions specific for the sensor, and control system for air flow rate and sensor temperature, are housed with the sensor in a compact, simple-to-exchange assembly. The instrument can be operated on solar power and uses cell phone technology to enable monitoring in remote locations. Data from field trials are presented here to demonstrate that both the accuracy and the stability of the instrument over periods of months are within a few parts-per-billion by volume. We show that common failure modes can be detected through measurement of signals available from the instrument. The combination of long-term stability, self-diagnosis, and simple, inexpensive repair means that the cost of operation and calibration of the instruments is significantly reduced in comparison with traditional reference instrumentation. These instruments enable the economical construction and operation of ozone monitoring networks of accuracy, time resolution and spatial density sufficient to resolve the local gradients that are characteristic of urban air pollution. (paper)

  10. Q2 - a very low level quantitative and qualitative waste assay and release certification system

    International Nuclear Information System (INIS)

    Bronson, F.L.

    1990-01-01

    Low level radioactive waste disposal is very expensive, especially when all of the handling transportation and documentation costs are included. However for most generators, a large fraction of this low level waste is not contaminated at all, or only slightly so. The paper describes the development and performance of a low level counter that is convenient to use, and that can accurately identify and quantify the radioactivity of any gamma emitter thing that can be placed in a 55 gallon (200 liter) container. These measurement results can be used to verify the absence of radioactivity at a very low levels (10 nCi (370 Bq)/sample), and to identify the nuclides and quantities present, while differentiating against natural radioactivity (Radium, Thorium, Potassium). These results can be used as part of a 10CFR20.302 waste stream exemption program, and thus allow significant savings and a less than 1 year payback at a typical nuclear power plant. The Q1 system is fully shielded to allow it's use in the low level radwaste storage area. The detectors are either 3 Intrinsic Germanium detectors or 2 large NaI detectors. The software is fully automated for simple operation. Correlation factors can be entered to estimate non-gamma emitters from pre-established correlations to other nuclides. Typical Ge detector sensitivities are 8 nCi (300 Bq) LLD for Cs-137 at 0.8 g/cc for a 10 minute count time. NaI detector systems can achieve the same LLD in a 1 minute count. 5 figs., 1 tab

  11. Maternal exposure to floricultural work during pregnancy, PON1 Q192R polymorphisms and the risk of low birth weight

    Energy Technology Data Exchange (ETDEWEB)

    Moreno-Banda, G.; Blanco-Munoz, J. [Population Health Research Center, National Institute of Public Health, Avenida Universidad 655, Colonia Santa Maria Ahuacatitlan, 62508 Cuernavaca, Morelos (Mexico); Lacasana, M., E-mail: marina.lacasana.easp@juntadeandalucia.es [Andalusian School of Public Health, Campus Universitario de la Cartuja, Cuesta del Observatorio, 4, 18080 Granada (Spain); CIBER of Epidemiology and Public Health (CIBERESP) (Spain); Rothenberg, S.J. [Population Health Research Center, National Institute of Public Health, Avenida Universidad 655, Colonia Santa Maria Ahuacatitlan, 62508 Cuernavaca, Morelos (Mexico); Center of Research and Advanced Studies, National Institute Polytechnic, Department of Toxicology, Av, Instituto Politecnico Nacional No. 2508, Col. San Pedro Zacatenco, Deleg. Gustavo A. Madero, 07360 Mexico, D.F. (Mexico); Aguilar-Garduno, C. [Andalusian School of Public Health, Campus Universitario de la Cartuja, Cuesta del Observatorio, 4, 18080 Granada (Spain); Andalusian Observatory of Environmental Health, Campus Universitario de la Cartuja, Cuesta del Observatorio, 4, 18080 Granada (Spain); Gamboa, R. [Department of Physiology, National Institute of Cardiology ' Ignacio Chavez' , Juan Badiano 4, Section XVI, 14080, Mexico DF (Mexico); Perez-Mendez, O. [Department of Molecular Biology and cardiovascular Diseases Genomic and Proteomic, National Institute of Cardiology ' Ignacio Chavez' , Juan Badiano 4, Section XVI, 14080, Mexico DF (Mexico)

    2009-10-15

    Background: Although there is evidence from animal studies of impaired reproductive function by exposure to organophosphates (OP), the effects on birth weight have not been sufficiently evaluated in epidemiological studies. Paraoxonase (PON1) detoxifies organophosphates by cleavage of active oxons. Some PON1 gene polymorphisms could reduce the enzyme activity and increase susceptibility to OP toxicity. Objective: To assess the association between maternal exposure to floriculture during pregnancy and the risk of low birth weight (< 2500 g) in their offspring, as well as to evaluate the interaction between this exposure and maternal genotype for PON1 Q192R polymorphisms. Materials and methods: A cross sectional study was carried out in two Mexican states (States of Mexico and Morelos) with high frequencies of greenhouse activity. We interviewed and collected blood samples from 264 females (floriculturists or partners of floricultural workers) who became pregnant during the 10 years prior to the interview. The questionnaire measured socioeconomic characteristics, tobacco and alcohol consumption, diseases and occupational and reproductive history. We also applied a food frequency questionnaire. Information was obtained pertaining to 467 pregnancies. DNA was extracted from white cells, and PON1 genotype was determined by Restriction Fragment Length Polymorphism for Q192R polymorphisms. Results were analyzed with generalized estimating equations models. Results: After adjusting for potential confounders, we detected a statistically significant interaction between maternal exposure to flower growing work during pregnancy and PON1 Q192R polymorphisms on risk of low birth weight. The risk of having a baby with LBW is nearly six times higher if a mother is a floriculture worker during pregnancy and has PON1 192RR genotype (OR 5.93, 95% CI 1.28, 27.5). Conclusion: These results suggest that the interaction between maternal floriculture work during pregnancy and 192RR PON1

  12. Maternal exposure to floricultural work during pregnancy, PON1 Q192R polymorphisms and the risk of low birth weight

    International Nuclear Information System (INIS)

    Moreno-Banda, G.; Blanco-Munoz, J.; Lacasana, M.; Rothenberg, S.J.; Aguilar-Garduno, C.; Gamboa, R.; Perez-Mendez, O.

    2009-01-01

    Background: Although there is evidence from animal studies of impaired reproductive function by exposure to organophosphates (OP), the effects on birth weight have not been sufficiently evaluated in epidemiological studies. Paraoxonase (PON1) detoxifies organophosphates by cleavage of active oxons. Some PON1 gene polymorphisms could reduce the enzyme activity and increase susceptibility to OP toxicity. Objective: To assess the association between maternal exposure to floriculture during pregnancy and the risk of low birth weight (< 2500 g) in their offspring, as well as to evaluate the interaction between this exposure and maternal genotype for PON1 Q192R polymorphisms. Materials and methods: A cross sectional study was carried out in two Mexican states (States of Mexico and Morelos) with high frequencies of greenhouse activity. We interviewed and collected blood samples from 264 females (floriculturists or partners of floricultural workers) who became pregnant during the 10 years prior to the interview. The questionnaire measured socioeconomic characteristics, tobacco and alcohol consumption, diseases and occupational and reproductive history. We also applied a food frequency questionnaire. Information was obtained pertaining to 467 pregnancies. DNA was extracted from white cells, and PON1 genotype was determined by Restriction Fragment Length Polymorphism for Q192R polymorphisms. Results were analyzed with generalized estimating equations models. Results: After adjusting for potential confounders, we detected a statistically significant interaction between maternal exposure to flower growing work during pregnancy and PON1 Q192R polymorphisms on risk of low birth weight. The risk of having a baby with LBW is nearly six times higher if a mother is a floriculture worker during pregnancy and has PON1 192RR genotype (OR 5.93, 95% CI 1.28, 27.5). Conclusion: These results suggest that the interaction between maternal floriculture work during pregnancy and 192RR PON1

  13. q-Derivatives, quantization methods and q-algebras

    International Nuclear Information System (INIS)

    Twarock, Reidun

    1998-01-01

    Using the example of Borel quantization on S 1 , we discuss the relation between quantization methods and q-algebras. In particular, it is shown that a q-deformation of the Witt algebra with generators labeled by Z is realized by q-difference operators. This leads to a discrete quantum mechanics. Because of Z, the discretization is equidistant. As an approach to a non-equidistant discretization of quantum mechanics one can change the Witt algebra using not the number field Z as labels but a quadratic extension of Z characterized by an irrational number τ. This extension is denoted as quasi-crystal Lie algebra, because this is a relation to one-dimensional quasicrystals. The q-deformation of this quasicrystal Lie algebra is discussed. It is pointed out that quasicrystal Lie algebras can be considered also as a 'deformed' Witt algebra with a 'deformation' of the labeling number field. Their application to the theory is discussed

  14. Study protocol for The Emory 3q29 Project: evaluation of neurodevelopmental, psychiatric, and medical symptoms in 3q29 deletion syndrome.

    Science.gov (United States)

    Murphy, Melissa M; Lindsey Burrell, T; Cubells, Joseph F; España, Roberto Antonio; Gambello, Michael J; Goines, Katrina C B; Klaiman, Cheryl; Li, Longchuan; Novacek, Derek M; Papetti, Ava; Sanchez Russo, Rossana Lucia; Saulnier, Celine A; Shultz, Sarah; Walker, Elaine; Mulle, Jennifer Gladys

    2018-06-08

    3q29 deletion syndrome is caused by a recurrent hemizygous 1.6 Mb deletion on the long arm of chromosome 3. The syndrome is rare (1 in 30,000 individuals) and is associated with mild to moderate intellectual disability, increased risk for autism and anxiety, and a 40-fold increased risk for schizophrenia, along with a host of physical manifestations. However, the disorder is poorly characterized, the range of manifestations is not well described, and the underlying molecular mechanism is not understood. We designed the Emory 3q29 Project to document the range of neurodevelopmental and psychiatric manifestations associated with 3q29 deletion syndrome. We will also create a biobank of samples from our 3q29 deletion carriers for mechanistic studies, which will be a publicly-available resource for qualified investigators. The ultimate goals of our study are three-fold: first, to improve management and treatment of 3q29 deletion syndrome. Second, to uncover the molecular mechanism of the disorder. Third, to enable cross-disorder comparison with other rare genetic syndromes associated with neuropsychiatric phenotypes. We will ascertain study subjects, age 6 and older, from our existing registry ( 3q29deletion.org ). Participants and their families will travel to Atlanta, GA for phenotypic assessments, with particular emphasis on evaluation of anxiety, cognitive ability, autism symptomatology, and risk for psychosis via prodromal symptoms and syndromes. Evaluations will be performed using standardized instruments. Structural, diffusion, and resting-state functional MRI data will be collected from eligible study participants. We will also collect blood from the 3q29 deletion carrier and participating family members, to be banked at the NIMH Repository and Genomics Resource (NRGR). The study of 3q29 deletion has the potential to transform our understanding of complex disease. Study of individuals with the deletion may provide insights into long term care and management of

  15. Further psychometric validation of the BODY-Q: ability to detect change following bariatric surgery weight gain and loss.

    Science.gov (United States)

    Klassen, Anne F; Cano, Stefan J; Kaur, Manraj; Breitkopf, Trisia; Pusic, Andrea L

    2017-11-25

    Recent systematic reviews have identified that current patient-reported outcome instruments have content limitations when used to measure change following bariatric surgery. The aim of this study was to measure change after bariatric surgery using the BODY-Q, a PRO instrument designed for weight loss and body contouring. The BODY-Q is composed of 18 independently functioning scales and an obesity-specific symptom checklist that measure appearance, health-related quality of life (HR-QOL) and experience of health-care. The sample for this study included patients who were exploring or seeking bariatric surgery in Hamilton (Canada) at the time of the BODY-Q field-test study and who agreed to further contact from the research team. These patients were invited to complete 12 BODY-Q scales and the symptom checklist between 7 June 2016 and 29 November 2016. Data were collected online (REDCap) and via postal surveys. Clinical change was measured using paired t-tests with effect sizes and standardized response means. The survey was completed by 58 of 89 (65%) pre-bariatric participants from the original BODY-Q field-test sample. The non-participants did not differ from participants in terms of age, gender, ethnicity, BMI or initial BODY-Q scale scores. Participants who had undergone bariatric surgery had a mean BMI of 49 (SD = 7) at time 1 and 35 (SD = 7) at time 2. Time since bariatric surgery was on average 2 years (SD = 0.5) (range 0.4 to 3 years). Percentage total weight loss ranged from 12 to 51 (mean 31, SD = 9). The difference in the proportion of patients to report an obesity-specific symptom on the BODY-Q checklist was significantly lower at follow-up for 5 of 10 symptoms. Participants improved on BODY-Q scales measuring appearance (of abdomen, back, body, buttocks, hips/outer thighs, inner thigh), body image and physical function (p weight loss. BODY-Q scales were responsive to measuring clinical change associated with weight loss 2 years after

  16. Spectroscopic investigation of plasma electrolytic borocarburizing on q235 low-carbon steel

    Energy Technology Data Exchange (ETDEWEB)

    Liu, Run [Key Laboratory for Beam Technology and Materials Modification of Ministry of Education, College of Nuclear Science and Technology, Beijing Normal University, Beijing 100875 (China); Beijing Radiation Center, Beijing 100875 (China); Zhenjiang Watercraft College, Zhenjiang 212000, Jiangsu (China); Wang, Bin; Wu, Jie [Key Laboratory for Beam Technology and Materials Modification of Ministry of Education, College of Nuclear Science and Technology, Beijing Normal University, Beijing 100875 (China); Beijing Radiation Center, Beijing 100875 (China); Xue, Wenbin, E-mail: xuewb@bnu.edu.cn [Key Laboratory for Beam Technology and Materials Modification of Ministry of Education, College of Nuclear Science and Technology, Beijing Normal University, Beijing 100875 (China); Beijing Radiation Center, Beijing 100875 (China); Jin, Xiaoyue; Du, Jiancheng; Hua, Ming [Key Laboratory for Beam Technology and Materials Modification of Ministry of Education, College of Nuclear Science and Technology, Beijing Normal University, Beijing 100875 (China); Beijing Radiation Center, Beijing 100875 (China)

    2014-12-01

    Highlights: • The plasma discharge behaviors for PEB/C on steels were evaluated by OES. • Electron temperature, concentration, atomic ionization degree were calculated. • The decomposition mechanism of electrolyte and was analyzed. - Abstract: A plasma electrolytic borocarburizing process (PEB/C) in borax electrolyte with glycerin additive was employed to fabricate a hardening layer on Q235 low-carbon steel. Optical emission spectroscopy (OES) was utilized to investigate the spectroscopy characteristics of plasma discharge around the steel during PEB/C process. Some plasma parameters were calculated in terms of OES. The electron temperature and electron concentration in plasma discharge zone is about 3000–12,000 K and 2 × 10{sup 22} m{sup −3}–1.4 × 10{sup 23} m{sup −3}. The atomic ionization degrees of iron, carbon and boron are 10{sup −16}–10{sup −3}, and 10{sup −23}–10{sup −6}, 10{sup −19}–10{sup −4}, respectively, which depend on discharge time. The surface morphology and cross-sectional microstructure of PEB/C hardening layer were observed, and the electrolyte decomposition and plasma discharge behaviors were discussed.

  17. Spectroscopic investigation of plasma electrolytic borocarburizing on q235 low-carbon steel

    International Nuclear Information System (INIS)

    Liu, Run; Wang, Bin; Wu, Jie; Xue, Wenbin; Jin, Xiaoyue; Du, Jiancheng; Hua, Ming

    2014-01-01

    Highlights: • The plasma discharge behaviors for PEB/C on steels were evaluated by OES. • Electron temperature, concentration, atomic ionization degree were calculated. • The decomposition mechanism of electrolyte and was analyzed. - Abstract: A plasma electrolytic borocarburizing process (PEB/C) in borax electrolyte with glycerin additive was employed to fabricate a hardening layer on Q235 low-carbon steel. Optical emission spectroscopy (OES) was utilized to investigate the spectroscopy characteristics of plasma discharge around the steel during PEB/C process. Some plasma parameters were calculated in terms of OES. The electron temperature and electron concentration in plasma discharge zone is about 3000–12,000 K and 2 × 10 22 m −3 –1.4 × 10 23 m −3 . The atomic ionization degrees of iron, carbon and boron are 10 −16 –10 −3 , and 10 −23 –10 −6 , 10 −19 –10 −4 , respectively, which depend on discharge time. The surface morphology and cross-sectional microstructure of PEB/C hardening layer were observed, and the electrolyte decomposition and plasma discharge behaviors were discussed

  18. Development of Application Programming Tool for Safety Grade PLC (POSAFE-Q)

    International Nuclear Information System (INIS)

    Koo, Kyungmo; You, Byungyong; Kim, Tae-Wook; Cho, Sengjae; Lee, Jin S.

    2006-01-01

    The pSET (POSAFE-Q Software Engineering Tool) is an application programming tool of the POSAFE-Q which is a safety graded programmable logic controller (PLC) developed for the reactor protect system of the nuclear power plant. The pSET provides an integrated development environment (IDE) which includes editors, compiler, simulator, down loader, debugger, and monitor. The pSET supports the IEC61131-3 standard software model and languages such as LD (ladder diagram) and FBD (function block diagram) which are two of the most widely used PLC programming languages in industry fields. The pSET will also support SFC (sequential function chart) language. The pSET is developed as a part of a Korea Nuclear Instrumentation and Control System (KNICS) project

  19. Siblings with opposite chromosome constitutions, dup(2q)/del(7q) and del(2q)/dup(7q).

    Science.gov (United States)

    Shim, Sung Han; Shim, Jae Sun; Min, Kyunghoon; Lee, Hee Song; Park, Ji Eun; Park, Sang Hee; Hwang, Euna; Kim, Minyoung

    2014-01-15

    Chromosome 7q36 microdeletion syndrome is a rare genomic disorder characterized by underdevelopment of the brain, microcephaly, anomalies of the sex organs, and language problems. Developmental delay, intellectual disability, autistic spectrum disorders, BDMR syndrome, and unusual facial morphology are the key features of the chromosome 2q37 microdeletion syndrome. A genetic screening for two brothers with global developmental delay using high-resolution chromosomal analysis and subtelomeric multiplex ligation-dependent probe amplification revealed subtelomeric rearrangements on the same sites of 2q37.2 and 7q35, with reversed deletion and duplication. Both of them showed dysmorphic facial features, severe disability of physical and intellectual development, and abnormal genitalia with differential abnormalities in their phenotypes. The family did not have abnormal genetic phenotypes. According to the genetic analysis of their parents, adjacent-1 segregation from their mother's was suggested as a mechanism of their gene mutation. By comparing the phenotypes of our patients with previous reports on similar patients, we tried to obtain the information of related genes and their chromosomal locations. © 2013.

  20. Some approximation properties of ( p , q $(p,q$ -Bernstein operators

    Directory of Open Access Journals (Sweden)

    Shin Min Kang

    2016-06-01

    Full Text Available Abstract This paper is concerned with the ( p , q $(p,q$ -analog of Bernstein operators. It is proved that, when the function is convex, the ( p , q $(p,q$ -Bernstein operators are monotonic decreasing, as in the classical case. Also, some numerical examples based on Maple algorithms that verify these properties are considered. A global approximation theorem by means of the Ditzian-Totik modulus of smoothness and a Voronovskaja type theorem are proved.

  1. Study of the AC machines winding having fractional q

    Science.gov (United States)

    Bespalov, V. Y.; Sidorov, A. O.

    2018-02-01

    The winding schemes with a fractional numbers of slots per pole and phase q have been known and used for a long time. However, in the literature on the low-noise machines design there are not recommended to use. Nevertheless, fractional q windings have been realized in many applications of special AC electrical machines, allowing to improve their performance, including vibroacoustic one. This paper deals with harmonic analysis of windings having integer and fractional q in permanent magnet synchronous motors, a comparison of their characteristics is performed, frequencies of subharmonics are revealed. Optimal winding pitch design is found giving reduce the amplitudes of subharmonics. Distribution factors for subharmonics, fractional and high-order harmonics are calculated, results analysis is represented, allowing for giving recommendations how to calculate distribution factors for different harmonics when q is fractional.

  2. The Basic Design Report of the 40M SANS Instrument

    Energy Technology Data Exchange (ETDEWEB)

    Han, Young Soo; Lee, Chang Hee; Hwang, Dong Gil; Kim, Hak Rho [Korea Atomic Energy Research Institute, Daejeon (Korea, Republic of); Kim, Tae Hwan; Choi, Sung Min [Korea Advanced Institute of Science and Technology, Daejeon (Korea, Republic of)

    2006-04-15

    The HANARO cold neutron research facility project was launched on July 1, 2003. A state of the art SANS instrument was selected as a top-priority instrument by an instrument selection committee, which consisted of domestic users and HANARO personnel. An instrument development team and an international and domestic instrument advisory team were formulated. The guide and the instrument simulation were performed using Vitess software and the optimum basic design was completed based on the simulation results and the international advisory team reviews. The optimum design of the guide for the 40M SANS instrument was completed and the optimum basic design of the 40M the SANS instrument was also completed based on the Vitess simulation results. The Q range of the instrument will cover from 0.0008 to 1.0 A-1 and the maximum flux at a sample position can reach about 5.5x10 7 n/cm2sec. The simulation results and the basic design product will be used for the detailed design and the construction of the SANS instrument. The simulation results could be applied to the development of the other instrument.

  3. On alternative q-Weibull and q-extreme value distributions: Properties and applications

    Science.gov (United States)

    Zhang, Fode; Ng, Hon Keung Tony; Shi, Yimin

    2018-01-01

    Tsallis statistics and Tsallis distributions have been attracting a significant amount of research work in recent years. Importantly, the Tsallis statistics, q-distributions have been applied in different disciplines. Yet, a relationship between some existing q-Weibull distributions and q-extreme value distributions that is parallel to the well-established relationship between the conventional Weibull and extreme value distributions through a logarithmic transformation has not be established. In this paper, we proposed an alternative q-Weibull distribution that leads to a q-extreme value distribution via the q-logarithm transformation. Some important properties of the proposed q-Weibull and q-extreme value distributions are studied. Maximum likelihood and least squares estimation methods are used to estimate the parameters of q-Weibull distribution and their performances are investigated through a Monte Carlo simulation study. The methodologies and the usefulness of the proposed distributions are illustrated by fitting the 2014 traffic fatalities data from The National Highway Traffic Safety Administration.

  4. Planck 2013 results. IV. Low Frequency Instrument beams and window functions

    CERN Document Server

    Aghanim, N; Arnaud, M; Ashdown, M; Atrio-Barandela, F; Aumont, J; Baccigalupi, C; Banday, A J; Barreiro, R B; Battaner, E; Benabed, K; Benoît, A; Benoit-Lévy, A; Bernard, J -P; Bersanelli, M; Bielewicz, P; Bobin, J; Bock, J J; Bonaldi, A; Bond, J R; Borrill, J; Bouchet, F R; Bridges, M; Bucher, M; Burigana, C; Butler, R C; Cardoso, J -F; Catalano, A; Chamballu, A; Chiang, L -Y; Christensen, P R; Church, S; Colombi, S; Colombo, L P L; Crill, B P; Curto, A; Cuttaia, F; Danese, L; Davies, R D; Davis, R J; de Bernardis, P; de Rosa, A; de Zotti, G; Delabrouille, J; Dickinson, C; Diego, J M; Dole, H; Donzelli, S; Doré, O; Douspis, M; Dupac, X; Efstathiou, G; Enßlin, T A; Eriksen, H K; Finelli, F; Forni, O; Frailis, M; Franceschi, E; Gaier, T C; Galeotta, S; Ganga, K; Giard, M; Giraud-Héraud, Y; González-Nuevo, J; Górski, K M; Gratton, S; Gregorio, A; Gruppuso, A; Hansen, F K; Hanson, D; Harrison, D; Henrot-Versillé, S; Hernández-Monteagudo, C; Herranz, D; Hildebrandt, S R; Hivon, E; Hobson, M; Holmes, W A; Hornstrup, A; Hovest, W; Huffenberger, K M; Jaffe, T R; Jaffe, A H; Jewell, J; Jones, W C; Juvela, M; Kangaslahti, P; Keihänen, E; Keskitalo, R; Kiiveri, K; Kisner, T S; Knoche, J; Knox, L; Kunz, M; Kurki-Suonio, H; Lagache, G; Lähteenmäki, A; Lamarre, J -M; Lasenby, A; Laureijs, R J; Lawrence, C R; Leahy, J P; Leonardi, R; Lesgourgues, J; Liguori, M; Lilje, P B; Lindholm, V; Linden-Vørnle, M; López-Caniego, M; Lubin, P M; Macías-Pérez, J F; Maino, D; Mandolesi, N; Maris, M; Marshall, D J; Martin, P G; Martínez-González, E; Masi, S; Matarrese, S; Matthai, F; Mazzotta, P; Meinhold, P R; Melchiorri, A; Mendes, L; Mennella, A; Migliaccio, M; Mitra, S; Moneti, A; Montier, L; Morgante, G; Mortlock, D; Moss, A; Munshi, D; Naselsky, P; Natoli, P; Netterfield, C B; Nørgaard-Nielsen, H U; Novikov, D; Novikov, I; O'Dwyer, I J; Osborne, S; Paci, F; Pagano, L; Paoletti, D; Partridge, B; Pasian, F; Patanchon, G; Perdereau, O; Perotto, L; Perrotta, F; Pierpaoli, E; Pietrobon, D; Plaszczynski, S; Platania, P; Pointecouteau, E; Polenta, G; Ponthieu, N; Popa, L; Poutanen, T; Pratt, G W; Prézeau, G; Prunet, S; Puget, J -L; Rachen, J P; Rebolo, R; Reinecke, M; Remazeilles, M; Ricciardi, S; Riller, T; Rocha, G; Rosset, C; Roudier, G; Rubiño-Martín, J A; Rusholme, B; Sandri, M; Santos, D; Scott, D; Seiffert, M D; Shellard, E P S; Spencer, L D; Starck, J -L; Stolyarov, V; Stompor, R; Sureau, F; Sutton, D; Suur-Uski, A -S; Sygnet, J -F; Tauber, J A; Tavagnacco, D; Terenzi, L; Toffolatti, L; Tomasi, M; Tristram, M; Tucci, M; Tuovinen, J; Türler, M; Umana, G; Valenziano, L; Valiviita, J; Van Tent, B; Varis, J; Vielva, P; Villa, F; Vittorio, N; Wade, L A; Wandelt, B D; Zacchei, A; Zonca, A

    2014-01-01

    This paper presents the characterization of the in-flight beams, the beam window functions and the associated uncertainties for the Planck Low Frequency Instrument (LFI). Knowledge of the beam profiles is necessary for determining the transfer function to go from the observed to the actual sky anisotropy power spectrum. The main beam distortions affect the beam window function, complicating the reconstruction of the anisotropy power spectrum at high multipoles, whereas the sidelobes affect the low and intermediate multipoles. The in-flight assessment of the LFI main beams relies on the measurements performed during Jupiter observations. By stacking the data from multiple Jupiter transits, the main beam profiles are measured down to -20 dB at 30 and 44 GHz, and down to -25 dB at 70 GHz. The main beam solid angles are determined to better than 0.2% at each LFI frequency band. The Planck pre-launch optical model is conveniently tuned to characterize the main beams independently of any noise effects. This approac...

  5. Chromosome 10q tetrasomy: First reported case

    Energy Technology Data Exchange (ETDEWEB)

    Blackston, R.D.; May, K.M.; Jones, F.D. [Emory Univ., Atlanta, GA (United States)] [and others

    1994-09-01

    While there are several reports of trisomy 10q (at least 35), we are not aware of previous cases of 10q tetrasomy. We present what we believe to be the initial report of such a case. R.J. is a 6 1/2 year old white male who presented with multiple dysmorphic features, marked articulation problems, hyperactivity, and developmental delays. He is the product of a term uncomplicated pregnancy. There was a normal spontaneous vaginal delivery with a birth weight of 6 lbs. 4oz. and length was 19 1/2 inch. Dysmorphic features include small size, an asymmetrically small head, low set ears with overfolded helixes, bilateral ptosis, downslanting eyes, right eye esotropia, prominent nose, asymmetric facies, high palate, mild pectus excavatum deformity of chest, and hyperextensible elbow joints. The patient is in special needs classes for mildly mentally handicapped students. Chromosome analysis at a resolution of 800 bands revealed a complex rearrangement of chromosomes 10 and 11. The segment 10q25.3 to q16.3 appears to be inverted and duplicated within the long arm of chromosome 10 at band q25.3 and the same segment of chromosome 10 is present on the terminal end of the short arm of chromosome 11. There is no visible loss of material from chromosome 11. Fluorescence in situ hybridization was performed with a chromosome 10 specific {open_quotes}paint{close_quotes} to confirm that all of the material on the abnormal 10 and the material on the terminal short arm of 11 was from chromosome 10. Thus, it appears that the segment 10q25.3 to q26.3 is present in four copies. Parental chromosome studies are normal. We compared findings which differ in that the case of 10q tetrasomy did not have prenatal growth deficiency, microphthalmia, cleft palate, digital anomalies, heart, or renal defects. Whereas most cases of 10q trisomy are said to have severe mental deficiency, our case of 10q tetrasomy was only mildly delayed. We report this first apparent cited case of 10q tetrasomy.

  6. Present status and plans for experiments at the Q3D of Strasbourg

    International Nuclear Information System (INIS)

    Coffin, J.P.; Jundt, F.; Rebmeister, R.; Seltz, R.; Wagner, P.

    1979-01-01

    In describing the Q3D spectrometer of Strasbourg, features with characteristics particular to this instrument are discussed. The light ion counter and the heavy ion counter which have been developed to equip the focal plane are described. Three experiments already undertaken with the facility are briefly mentioned and the future research programme outlined. (UK)

  7. Investigation into the limits of perturbation theory at low Q"2 using HERA deep inelastic scattering data

    International Nuclear Information System (INIS)

    Abt, I.; Myronenko, V.; Wichmann, K.; Wing, M.

    2017-01-01

    A phenomenological study of the final combined HERA data on inclusive deep inelastic scattering (DIS) has been performed. The data are presented and investigated for a kinematic range extending from values of the four-momentum transfer, Q"2, above 10"4 GeV"2 down to the lowest values observable at HERA of Q"2=0.045 GeV"2 and Bjorken x, x_B_j=6.10"-"7. The data are well described by fits based on perturbative quantum chromodynamics (QCD) using collinear factorisation and evolution of the parton densities encompassed in the DGLAP formalism from the highest Q"2 down to Q"2 of a few GeV"2. The Regge formalism with the soft Pomeron pole can describe the data up to Q"2∼0.65 GeV"2. The complete data set can be described by a new fit using the Abramowicz-Levin-Levy-Maor (ALLM) parameterisation. The region between the Regge and the perturbative QCD regimes is of particular interest.

  8. Preventing Raman Lasing in High-Q WGM Resonators

    Science.gov (United States)

    Savchenkov, Anatoliy; Matsko, Andrey; Strekalov, Dmitry; Maleki, Lute

    2007-01-01

    A generic design has been conceived to suppress the Raman effect in whispering- gallery-mode (WGM) optical resonators that have high values of the resonance quality factor (Q). Although it is possible to exploit the Raman effect (even striving to maximize the Raman gain to obtain Raman lasing), the present innovation is intended to satisfy a need that arises in applications in which the Raman effect inhibits the realization of the full potential of WGM resonators as frequency-selection components. Heretofore, in such applications, it has been necessary to operate high-Q WGM resonators at unattractively low power levels to prevent Raman lasing. (The Raman-lasing thresholds of WGM optical resonators are very low and are approximately proportional to Q(sup -2)). Heretofore, two ways of preventing Raman lasting at high power levels have been known, but both entail significant disadvantages: A resonator can be designed so that the optical field is spread over a relatively large mode volume to bring the power density below the threshold. For any given combination of Q and power level, there is certain mode volume wherein Raman lasing does not start. Unfortunately, a resonator that has a large mode volume also has a high spectral density, which is undesirable in a typical photonic application. A resonator can be cooled to the temperature of liquid helium, where the Raman spectrum is narrower and, therefore, the Raman gain is lower. However, liquid-helium cooling is inconvenient. The present design overcomes these disadvantages, making it possible to operate a low-spectral-density (even a single-mode) WGM resonator at a relatively high power level at room temperature, without risk of Raman lasing.

  9. Effect of Q&P heat treatment on fine microstructure and mechanical properties of a low-alloy medium-carbon steel

    Science.gov (United States)

    Jafari, Rahim; Kheirandish, Shahram; Mirdamadi, Shamsoddin

    2018-01-01

    The current research investigates the effect of ultrafine microstructure resulted from Quench and Partitioning (Q&P) process on obtaining ultra-high strengths in a low-alloy steel with 4wt.% carbon. The purpose of Q&P heat treatment is to enrich the austenite with carbon by partitioning of carbon from supersaturated martensite to austenite, in order to stabilize it to the room temperature. The microstructure, consequently, is consists of martensite, retained austenite and in some conditions bainite. Two-step Q&P heat treatment with quench and partitioning temperatures equal to 120°C and 300°C respectively were applied to the samples at different times. Mechanical behavior was studied by tensile test. The microstructure of the samples was observed using SEM, and TEM and to quantify the amount of retained austenite X-ray diffraction was used. The retained austenite grain size was estimated to be about 0.5 µm and the highest amount of retained austenite obtained was 10 vol%. All samples showed a yield strength and a tensile strength of above 900MPa and 1500MP respectively. The yield strength increased with increase in partitioning time, whereas tensile strength showed an inverse behavior. The elongation in samples varied from 5% to 9% which seemed to not have a direct connection with the amount of retained austenite, but instead it was related to the ferritic structures formed during partitioning such as coalesced martensite, bainite and tempered martensite.

  10. Advances in High-Throughput Speed, Low-Latency Communication for Embedded Instrumentation (7th Annual SFAF Meeting, 2012)

    Energy Technology Data Exchange (ETDEWEB)

    Jordan, Scott

    2012-06-01

    Scott Jordan on "Advances in high-throughput speed, low-latency communication for embedded instrumentation" at the 2012 Sequencing, Finishing, Analysis in the Future Meeting held June 5-7, 2012 in Santa Fe, New Mexico.

  11. Replication the association of 2q32.2-q32.3 and 14q32.11 with hepatocellular carcinoma.

    Science.gov (United States)

    Chen, Wei; Wang, Mingquan; Zhang, Zhen; Tang, Huayang; Zuo, Xianbo; Meng, Xiangling; Xiong, Maoming; Zhou, Fusheng; Liang, Bo; Dai, Fen; Fang, Jun; Gao, Jinping; Zhu, Jun; Zhu, Yong; Wan, Hong; Wang, Miaofeng; Chan, Shixin; Sun, Liangdan

    2015-04-25

    Hepatocellular carcinoma (HCC) is a malignant tumor. The morbidity and mortality of HCC tend to ascend and become a serious threat to the population health. Genetic studies of HCC have identified several susceptibility loci of HCC. In this study, we aim to replicate the association of these loci in our samples from Chinese population and further investigate the genetic interaction. We selected 16 SNPs within 1p36.22, 2q32.2-q32.3, 3p21.33, 8p12, 14q32.11 and 21q21.3 and genotyped in 507 HCC patients and 3014 controls by using Sequenom MassARRAY system. Association analyses were performed by using PLINK 1.07. We observed that the STAT4 (2q32.2-q32.3) at rs7574865 (P=1.17×10(-3), OR=0.79) and EFCAB11 (14q32.11) at rs8013403 (P=1.54×10(-3), OR=0.80) were significantly associated with HCC in this study. In 3p21.33, genetic variant rs6795737 within GLB1 was also observed with suggestive evidence (P=9.98×10(-3), OR=0.84). In the interaction analysis, the pair of associated SNPs (rs7574865 within STAT4, rs8013403 within EFCAB11) generated evidence for interaction (P=4.10×10(-3)). In summary, our work first reported the association of 14q32.11 (EFCAB11) with HCC in Chinese Han population and revealed the genetic interaction between STAT4 (2q32.2-q32.3) and EFCAB11 (14q32.11) in HCC. Copyright © 2015 Elsevier B.V. All rights reserved.

  12. Compound Heterozygous Inheritance of Mutations in Coenzyme Q8A Results in Autosomal Recessive Cerebellar Ataxia and Coenzyme Q10 Deficiency in a Female Sib-Pair.

    Science.gov (United States)

    Jacobsen, Jessie C; Whitford, Whitney; Swan, Brendan; Taylor, Juliet; Love, Donald R; Hill, Rosamund; Molyneux, Sarah; George, Peter M; Mackay, Richard; Robertson, Stephen P; Snell, Russell G; Lehnert, Klaus

    2017-11-21

    Autosomal recessive ataxias are characterised by a fundamental loss in coordination of gait with associated atrophy of the cerebellum. There is significant clinical and genetic heterogeneity amongst inherited ataxias; however, an early molecular diagnosis is essential with low-risk treatments available for some of these conditions. We describe two female siblings who presented early in life with unsteady gait and cerebellar atrophy. Whole exome sequencing revealed compound heterozygous inheritance of two pathogenic mutations (p.Leu277Pro, c.1506+1G>A) in the coenzyme Q8A gene (COQ8A), a gene central to biosynthesis of coenzyme Q (CoQ). The paternally derived p.Leu277Pro mutation is predicted to disrupt a conserved motif in the substrate-binding pocket of the protein, resulting in inhibition of CoQ 10 production. The maternal c.1506+1G>A mutation destroys a canonical splice donor site in exon 12 affecting transcript processing and subsequent protein translation. Mutations in this gene can result in primary coenzyme Q 10 deficiency type 4, which is characterized by childhood onset of cerebellar ataxia and exercise intolerance, both of which were observed in this sib-pair. Muscle biopsies revealed unequivocally low levels of CoQ 10, and the siblings were subsequently established on a therapeutic dose of CoQ 10 with distinct clinical evidence of improvement after 1 year of treatment. This case emphasises the importance of an early and accurate molecular diagnosis for suspected inherited ataxias, particularly given the availability of approved treatments for some subtypes.

  13. THOR Ion Mass Spectrometer instrument - IMS

    Science.gov (United States)

    Retinò, Alessandro; Kucharek, Harald; Saito, Yoshifumi; Fraenz, Markus; Verdeil, Christophe; Leblanc, Frederic; Techer, Jean-Denis; Jeandet, Alexis; Macri, John; Gaidos, John; Granoff, Mark; Yokota, Shoichiro; Fontaine, Dominique; Berthomier, Matthieu; Delcourt, Dominique; Kistler, Lynn; Galvin, Antoniette; Kasahara, Satoshi; Kronberg, Elena

    2016-04-01

    Turbulence Heating ObserveR (THOR) is the first mission ever flown in space dedicated to plasma turbulence. Specifically, THOR will study how turbulent fluctuations at kinetic scales heat and accelerate particles in different turbulent environments within the near-Earth space. To achieve this goal, THOR payload is being designed to measure electromagnetic fields and particle distribution functions with unprecedented resolution and accuracy. Here we present the Ion Mass Spectrometer (IMS) instrument that will measure the full three-dimensional distribution functions of near-Earth main ion species (H+, He+, He++ and O+) at high time resolution (~ 150 ms for H+ , ~ 300 ms for He++) with energy resolution down to ~ 10% in the range 10 eV/q to 30 keV/q and angular resolution ~ 10°. Such high time resolution is achieved by mounting multiple sensors around the spacecraft body, in similar fashion to the MMS/FPI instrument. Each sensor combines a top-hat electrostatic analyzer with deflectors at the entrance together with a time-of-flight section to perform mass selection. IMS electronics includes a fast sweeping high voltage board that is required to make measurements at high cadence. Ion detection includes Micro Channel Plates (MCP) combined with Application-Specific Integrated Circuits (ASICs) for charge amplification, discrimination and time-to-digital conversion (TDC). IMS is being designed to address many of THOR science requirements, in particular ion heating and acceleration by turbulent fluctuations in foreshock, shock and magnetosheath regions. The IMS instrument is being designed and will be built by an international consortium of scientific institutes with main hardware contributions from France, USA, Japan and Germany.

  14. Complex Phenotype Associated with 17q21.31 Microdeletion

    Science.gov (United States)

    Dornelles-Wawruk, H.; Pic-Taylor, A.; Rosenberg, C.; Krepischi, A.C.V.; Safatle, H.P.N.; Ferrari, I.; Mazzeu, J.F.

    2013-01-01

    We report on a patient carrying a 17q21.31 microdeletion and exhibiting many common syndrome features, together with other clinical signs which have rarely or never been described to date. The detected 695-kb 17q21.31 deletion is larger than in most previously reported cases but is still probably the result of recombination between flanking low-copy repeats. Due to the complexity of the patient's clinical condition, together with the presence of 3 previously unreported symptoms, namely chronic anemia, cervical vertebrae arthrosis and vertebrae fusion, this case is an important addition to the existing knowledge about the 17q21.31 microdeletion syndrome. PMID:24167466

  15. Measurement of quantitative species diversity on reclaimed coal mine lands: A brief overview of the Wyoming regulatory proposal

    International Nuclear Information System (INIS)

    Vincent, R.B.

    1998-01-01

    The Wyoming Land Quality Division (LQD) Coal Rules and Regulations require mine operators to specify quantitative procedures for evaluating postmining species diversity and composition. Currently, permit commitments range from deferring to commit to a quantitative procedure until some future date to applying various similarity/diversity indices for comparison of reclaimed lands to native vegetation communities. Therefore, the LQD began trying to develop a standardized procedure to evaluate species diversity and composition, while providing operator flexibility. Review of several technical publications on the use of similarity and diversity indices, and other measurement techniques indicate that a consensus has not been reached on which procedure is most appropriate for use on reclaimed mine lands. In addition, implementation of many of the recommended procedures are not practical with regards to staff and data limitations. As a result, the LQD has developed an interim procedure, based on site-specific baseline data, to evaluate postmining species diversity and composition success with respect to bond release requests. This paper reviews many of the recommended procedures, outlines some of the pros and cons, and provides a specific example of how the proposed interim procedure was applied to an actual coal mine permit. Implementation of this or a similar procedure would allow for site-specific standardization of permits and regulatory requirements, thus reducing review time and reducing some of the subjectivity surrounding a component of the Wyoming bond release requirements

  16. Chromosome 12q24.31-q24.33 deletion causes multiple dysmorphic features and developmental delay: First mosaic patient and overview of the phenotype related to 12q24qter defects

    Directory of Open Access Journals (Sweden)

    Sakati Nadia

    2011-04-01

    Full Text Available Abstract Background Genomic imbalances of the 12q telomere are rare; only a few patients having 12q24.31-q24.33 deletions were reported. Interestingly none of these were mosaic. Although some attempts have been made to establish phenotype/genotype interaction for the deletions in this region, no clear relationship has been established to date. Results We have clinically screened more than 100 patients with dysmorphic features, mental retardation and normal karyotype using high density oligo array-CGH (aCGH and identified a ~9.2 Mb hemizygous interstitial deletion at the 12q telomere (Chromosome 12: 46,XY,del(12(q24.31q24.33 in a severely developmentally retarded patient having dysmorphic features such as low set ears, microcephaly, undescended testicles, bent elbow, kyphoscoliosis, and micropenis. Parents were found to be not carriers. MLPA experiments confirmed the aCGH result. Interphase FISH revealed mosaicism in cultured peripheral blood lymphocytes. Conclusions Since conventional G-Banding technique missed the abnormality; this work re-confirms that any child with unexplained developmental delay and systemic involvement should be studied by aCGH techniques. The FISH technique, however, would still be useful to further delineate the research work and identify such rare mosaicism. Among the 52 deleted genes, P2RX2, ULK1, FZD10, RAN, NCOR2 STX2, TESC, FBXW8, and TBX3 are noteworthy since they may have a role in observed phenotype.

  17. Qq(Q-bar)(q-bar)' states in chiral SU(3) quark model

    International Nuclear Information System (INIS)

    Zhang Haixia; Zhang Min; Zhang Zongye

    2007-01-01

    We study the masses of Qq(Q-bar)(q-bar)' states with J PC =0 ++ , 1 ++ , 1 +- and 2 ++ in the chiral SU(3) quark model, where Q is the heavy quark (c or b) and q(q') is the light quark (u,d or s). According to our numerical results, it is improbable to make the interpretation of [cn(c-bar)(n-bar)] 1 ++ and [cn(c-bar)(n-bar)] 2 ++ (n=u,d) states as X(3872) and Y(3940), respectively. However, it is interesting to find the tetraquarks in the bq(b-bar)(q-bar)' system. (authors)

  18. Planck 2013 results. II. Low Frequency Instrument data processing

    CERN Document Server

    Aghanim, N; Arnaud, M; Ashdown, M; Atrio-Barandela, F; Aumont, J; Baccigalupi, C; Banday, A J; Barreiro, R B; Battaner, E; Benabed, K; Benoît, A; Benoit-Lévy, A; Bernard, J -P; Bersanelli, M; Bielewicz, P; Bobin, J; Bock, J J; Bonaldi, A; Bonavera, L; Bond, J R; Borrill, J; Bouchet, F R; Bridges, M; Bucher, M; Burigana, C; Butler, R C; Cappellini, B; Cardoso, J -F; Catalano, A; Chamballu, A; Chen, X; Chiang, L -Y; Christensen, P R; Church, S; Colombi, S; Colombo, L P L; Crill, B P; Cruz, M; Curto, A; Cuttaia, F; Danese, L; Davies, R D; Davis, R J; de Bernardis, P; de Rosa, A; de Zotti, G; Delabrouille, J; Dickinson, C; Diego, J M; Dole, H; Donzelli, S; Doré, O; Douspis, M; Dupac, X; Efstathiou, G; Enßlin, T A; Eriksen, H K; Falvella, M C; Finelli, F; Forni, O; Frailis, M; Franceschi, E; Gaier, T C; Galeotta, S; Ganga, K; Giard, M; Giardino, G; Giraud-Héraud, Y; Gjerløw, E; González-Nuevo, J; Górski, K M; Gratton, S; Gregorio, A; Gruppuso, A; Hansen, F K; Hanson, D; Harrison, D; Henrot-Versillé, S; Hernández-Monteagudo, C; Herranz, D; Hildebrandt, S R; Hivon, E; Hobson, M; Holmes, W A; Hornstrup, A; Hovest, W; Huffenberger, K M; Jaffe, T R; Jaffe, A H; Jewell, J; Jones, W C; Juvela, M; Kangaslahti, P; Keihänen, E; Keskitalo, R; Kiiveri, K; Kisner, T S; Knoche, J; Knox, L; Kunz, M; Kurki-Suonio, H; Lagache, G; Lähteenmäki, A; Lamarre, J -M; Lasenby, A; Lattanzi, M; Laureijs, R J; Lawrence, C R; Leach, S; Leahy, J P; Leonardi, R; Lesgourgues, J; Liguori, M; Lilje, P B; Lindholm, V; Linden-Vørnle, M; López-Caniego, M; Lubin, P M; Macías-Pérez, J F; Maggio, G; Maino, D; Mandolesi, N; Maris, M; Marshall, D J; Martin, P G; Martínez-González, E; Masi, S; Matarrese, S; Matthai, F; Mazzotta, P; Meinhold, P R; Melchiorri, A; Mendes, L; Mennella, A; Migliaccio, M; Mitra, S; Moneti, A; Montier, L; Morgante, G; Mortlock, D; Moss, A; Munshi, D; Naselsky, P; Natoli, P; Netterfield, C B; Nørgaard-Nielsen, H U; Novikov, D; Novikov, I; O'Dwyer, I J; Osborne, S; Paci, F; Pagano, L; Paladini, R; Paoletti, D; Partridge, B; Pasian, F; Patanchon, G; Peel, M; Perdereau, O; Perotto, L; Perrotta, F; Pierpaoli, E; Pietrobon, D; Plaszczynski, S; Platania, P; Pointecouteau, E; Polenta, G; Ponthieu, N; Popa, L; Poutanen, T; Pratt, G W; Prézeau, G; Prunet, S; Puget, J -L; Rachen, J P; Reach, W T; Rebolo, R; Reinecke, M; Remazeilles, M; Ricciardi, S; Riller, T; Rocha, G; Rosset, C; Rossetti, M; Roudier, G; Rubiño-Martín, J A; Rusholme, B; Salerno, E; Sandri, M; Santos, D; Scott, D; Seiffert, M D; Shellard, E P S; Spencer, L D; Starck, J -L; Stolyarov, V; Stompor, R; Sureau, F; Sutton, D; Suur-Uski, A -S; Sygnet, J -F; Tauber, J A; Tavagnacco, D; Terenzi, L; Toffolatti, L; Tomasi, M; Tristram, M; Tucci, M; Tuovinen, J; Türler, M; Umana, G; Valenziano, L; Valiviita, J; Van Tent, B; Varis, J; Vielva, P; Villa, F; Vittorio, N; Wade, L A; Wandelt, B D; Watson, R; Wehus, I K; White, S D M; Wilkinson, A; Yvon, D; Zacchei, A; Zonca, A

    2014-01-01

    We describe the data processing pipeline of the Planck Low Frequency Instrument (LFI) data processing centre (DPC) to create and characterize full-sky maps based on the first 15.5 months of operations at 30, 44 and 70 GHz. In particular, we discuss the various steps involved in reducing the data, starting from telemetry packets through to the production of cleaned, calibrated timelines and calibrated frequency maps. Data are continuously calibrated using the modulation induced on the mean temperature of the cosmic microwave background radiation by the proper motion of the spacecraft. Sky signals other than the dipole are removed by an iterative procedure based on simultaneous fitting of calibration parameters and sky maps. Noise properties are estimated from time-ordered data after the sky signal has been removed, using a generalized least square map-making algorithm. A destriping code (Madam) is employed to combine radiometric data and pointing information into sky maps, minimizing the variance of correlated...

  19. GALAXI: Gallium anode low-angle x-ray instrument

    Directory of Open Access Journals (Sweden)

    Emmanuel Kentzinger

    2016-03-01

    Full Text Available The high brilliance laboratory small angle X-ray scattering instrument GALAXI, which is operated by JCNS, Forschungszentrum Jülich, permits the investigation of chemical correlations in bulk materials or of structures deposited on a surface at nanometre and mesoscopic length scales. The instrument is capable to perform GISAXS experiments in reflection at grazing incidence as well as SAXS experiments in transmission geometry. The X-ray flux on sample is comparable or higher than the one obtained at a comparable beamline at a second generation synchrotron radiation source.

  20. Riems influenza a typing array (RITA): An RT-qPCR-based low density array for subtyping avian and mammalian influenza a viruses.

    Science.gov (United States)

    Hoffmann, Bernd; Hoffmann, Donata; Henritzi, Dinah; Beer, Martin; Harder, Timm C

    2016-06-03

    Rapid and sensitive diagnostic approaches are of the utmost importance for the detection of humans and animals infected by specific influenza virus subtype(s). Cascade-like diagnostics starting with the use of pan-influenza assays and subsequent subtyping devices are normally used. Here, we demonstrated a novel low density array combining 32 TaqMan(®) real-time RT-PCR systems in parallel for the specific detection of the haemagglutinin (HA) and neuraminidase (NA) subtypes of avian and porcine hosts. The sensitivity of the newly developed system was compared with that of the pan-influenza assay, and the specificity of all RT-qPCRs was examined using a broad panel of 404 different influenza A virus isolates representing 45 different subtypes. Furthermore, we analysed the performance of the RT-qPCR assays with diagnostic samples obtained from wild birds and swine. Due to the open format of the array, adaptations to detect newly emerging influenza A virus strains can easily be integrated. The RITA array represents a competitive, fast and sensitive subtyping tool that requires neither new machinery nor additional training of staff in a lab where RT-qPCR is already established.

  1. Constitutional chromosomal events at 22q11 and 15q26 in a child with a pilocytic astrocytoma of the spinal cord.

    Science.gov (United States)

    Mascelli, Samantha; Severino, Mariasavina; Raso, Alessandro; Nozza, Paolo; Tassano, Elisa; Morana, Giovanni; De Marco, Patrizia; Merello, Elisa; Milanaccio, Claudia; Pavanello, Marco; Rossi, Andrea; Cama, Armando; Garrè, Maria Luisa; Capra, Valeria

    2014-01-01

    We report on a 9-years-old patient with mild intellectual disability, facial dimorphisms, bilateral semicircular canal dysplasia, periventricular nodular heterotopias, bilateral hippocampal malrotation and abnormal cerebellar foliation, who developed mild motor impairment and gait disorder due to a pilocytic astrocytoma of the spinal cord. Array-CGH analysis revealed two paternal inherited chromosomal events: a 484.3 Kb duplication on chromosome 15q26.3 and a 247 Kb deletion on 22q11.23. Further, a second de novo 1.5 Mb deletion on 22q11.21 occurred. Chromosome 22 at q11.2 and chromosome 15 at q24q26 are considered unstable regions subjected to copy number variations, i.e. structural alterations of genome, mediated by low copy repeat sequences or segmental duplications. The link between some structural CNVs, which compromise fundamental processes controlling DNA stability, and genomic disorders suggest a plausible scenario for cancer predisposition. Evaluation of the genes at the breakpoints cannot account simultaneously for the phenotype and tumour development in this patient. The two paternal inherited CNVs arguably are not pathogenic and do not contribute to the clinical manifestations. Similarly, although the de novo large deletion at 22q11.21 overlaps with the Di George (DGS) critical region and results in haploinsufficiency of genes compromising critical processes for DNA stability, this case lacks several hallmarks of DGS.

  2. Chromosome 15q24 microdeletion syndrome

    Directory of Open Access Journals (Sweden)

    Magoulas Pilar L

    2012-01-01

    Full Text Available Abstract Chromosome 15q24 microdeletion syndrome is a recently described rare microdeletion syndrome that has been reported in 19 individuals. It is characterized by growth retardation, intellectual disability, and distinct facial features including long face with high anterior hairline, hypertelorism, epicanthal folds, downslanting palpebral fissures, sparse and broad medial eyebrows, broad and/or depressed nasal bridge, small mouth, long smooth philtrum, and full lower lip. Other common findings include skeletal and digital abnormalities, genital abnormalities in males, hypotonia, behavior problems, recurrent infections, and eye problems. Other less frequent findings include hearing loss, growth hormone deficiency, hernias, and obesity. Congenital malformations, while rare, can be severe and include structural brain anomalies, cardiovascular malformations, congenital diaphragmatic hernia, intestinal atresia, imperforate anus, and myelomeningocele. Karyotypes are typically normal, and the deletions were detected in these individuals by array comparative genomic hybridization (aCGH. The deletions range in size from 1.7-6.1 Mb and usually result from nonallelic homologous recombination (NAHR between paralogous low-copy repeats (LCRs. The majority of 15q24 deletions have breakpoints that localize to one of five LCR clusters labeled LCR15q24A, -B, -C, -D, and -E. The smallest region of overlap (SRO spans a 1.2 Mb region between LCR15q24B to LCR15q24C. There are several candidate genes within the SRO, including CYP11A1, SEMA7A, CPLX3, ARID3B, STRA6, SIN3A and CSK, that may predispose to many of the clinical features observed in individuals with 15q24 deletion syndrome. The deletion occurred as a de novo event in all of the individuals when parents were available for testing. Parental aCGH and/or FISH studies are recommended to provide accurate genetic counseling and guidance regarding prognosis, recurrence risk, and reproductive options. Management

  3. High-fidelity quantum gates on quantum-dot-confined electron spins in low-Q optical microcavities

    Science.gov (United States)

    Li, Tao; Gao, Jian-Cun; Deng, Fu-Guo; Long, Gui-Lu

    2018-04-01

    We propose some high-fidelity quantum circuits for quantum computing on electron spins of quantum dots (QD) embedded in low-Q optical microcavities, including the two-qubit controlled-NOT gate and the multiple-target-qubit controlled-NOT gate. The fidelities of both quantum gates can, in principle, be robust to imperfections involved in a practical input-output process of a single photon by converting the infidelity into a heralded error. Furthermore, the influence of two different decay channels is detailed. By decreasing the quality factor of the present microcavity, we can largely increase the efficiencies of these quantum gates while their high fidelities remain unaffected. This proposal also has another advantage regarding its experimental feasibility, in that both quantum gates can work faithfully even when the QD-cavity systems are non-identical, which is of particular importance in current semiconductor QD technology.

  4. Long Term Analysis of Adaptive Low-Power Instrument Platform Power and Battery Performance

    Science.gov (United States)

    Edwards, T.; Bowman, J. R.; Clauer, C. R.

    2017-12-01

    Operation of the Autonomous Adaptive Low-Power Instrument Platform (AAL-PIP) by the Magnetosphere-Ionosphere Science Team (MIST) at Virginia Tech has been ongoing for about 10 years. These instrument platforms are deployed on the East Antarctic Plateau in remote locations that are difficult to access regularly. The systems have been designed to operate unattended for at least 5 years. During the Austral summer, the systems charge batteries using solar panels and power is provided by the batteries during the winter months. If the voltage goes below a critical level, the systems go into hibernation and wait for voltage from the solar panels to initiate a restart sequence to begin operation and battery charging. Our first system was deployed on the East Antarctic Plateau in 2008 and we report here on an analysis of the power and battery performance over multiple years and provide an estimate for how long these systems can operate before major battery maintenance must be performed.

  5. Extended q -Gaussian and q -exponential distributions from gamma random variables

    Science.gov (United States)

    Budini, Adrián A.

    2015-05-01

    The family of q -Gaussian and q -exponential probability densities fit the statistical behavior of diverse complex self-similar nonequilibrium systems. These distributions, independently of the underlying dynamics, can rigorously be obtained by maximizing Tsallis "nonextensive" entropy under appropriate constraints, as well as from superstatistical models. In this paper we provide an alternative and complementary scheme for deriving these objects. We show that q -Gaussian and q -exponential random variables can always be expressed as a function of two statistically independent gamma random variables with the same scale parameter. Their shape index determines the complexity q parameter. This result also allows us to define an extended family of asymmetric q -Gaussian and modified q -exponential densities, which reduce to the standard ones when the shape parameters are the same. Furthermore, we demonstrate that a simple change of variables always allows relating any of these distributions with a beta stochastic variable. The extended distributions are applied in the statistical description of different complex dynamics such as log-return signals in financial markets and motion of point defects in a fluid flow.

  6. Instrumentation amplifier implements second-order active low-pass filter with high gain factor

    International Nuclear Information System (INIS)

    Blomqvist, Kim H; Eskelinen, Pekka; Sepponen, Raimo E

    2011-01-01

    A single-ended second-order active low-pass filter can simultaneously provide high gain factor and dc voltage subtraction. This makes it possible to reduce the number of components and signal processing stages needed in an application where small voltage changes are measured on the top of large dc voltage masked by a large amplitude oscillating carrier. The filter described in this paper is constructed from a conventional 3-op-amp instrumentation amplifier and five passive circuit elements. (technical design note)

  7. Bindi tattoo on forehead: success with modified R-20 technique using low fluence q-switched nd yag laser: a case report.

    Science.gov (United States)

    Zawar, Vijay; Sarda, Aarti; De, Abhishek

    2014-01-01

    Bindi tattoo on the forehead, is one of the cultural practice in Indian women from rural areas. Many patients are not pleased with the appearance of their tattoo and thus seek removal. The development of quality-switched lasers has revolutionized the removal of unwanted tattoos. However, despite multiple treatment sessions, the efficacy is often found to be limited. We herein report a case of green-blue bindi tattoo which failed to clear after 8 sessions of Q-switched Nd YAG laser. The tattoo significantly cleared with R-20 method using low fluence Q-switched Nd YAG Laser. R-20 technique seems to be an effective method of tattoo removal and might be a boon for patients who are reluctant to pursue laser treatment because of fear of expenditure, side effects and uncertainty of result. We report efficacy of R-20 technique for a bindi tattoo on forehead.

  8. Increasing Laser Stability with Improved Electronic Instruments

    Science.gov (United States)

    Troxel, Daylin; Bennett, Aaron; Erickson, Christopher J.; Jones, Tyler; Durfee, Dallin S.

    2010-03-01

    We present several electronic instruments developed to implement an ultra-stable laser lock. These instruments include a high speed, low noise homodyne photo-detector; an ultrahigh stability, low noise current driver with high modulation bandwidth and digital control; a high-speed, low noise PID controller; a low-noise piezo driver; and a laser diode temperature controller. We will present the theory of operation for these instruments, design and construction techniques, and essential characteristics for each device.

  9. High-Q Bandpass Comb Filter for Mains Interference Extraction

    Directory of Open Access Journals (Sweden)

    Neycheva T.

    2009-12-01

    Full Text Available This paper presents a simple digital high-Q bandpass comb filter for power-line (PL or other periodical interference extraction. The filter concept relies on a correlated signal average resulting in alternating constructive and destructive spectrum interference i.e. the so-called comb frequency response. The presented filter is evaluated by Matlab simulations with real ECG signal contaminated with low amplitude PL interference. The made simulations show that this filter accurately extract the PL interference. It has high-Q notches only at PL odd harmonics and is appropriate for extraction of any kind of odd harmonic interference including rectangular shape. The filter is suitable for real-time operation with popular low-cost microcontrollers.

  10. Core barrier formation near integer q surfaces in DIII-D

    International Nuclear Information System (INIS)

    Austin, M. E.; Gentle, K. W.; Burrell, K. H.; Waltz, R. E.; Gohil, P.; Greenfield, C. M.; Groebner, R. J.; Petty, C. C.; Prater, R.; Heidbrink, W. W.; Luo, Y.; Kinsey, J. E.; Makowski, M. A.; McKee, G. R.; Shafer, M. W.; Nazikian, R.; Rhodes, T. L.; Van Zeeland, M. A.

    2006-01-01

    Recent DIII-D experiments have significantly improved the understanding of internal transport barriers (ITBs) that are triggered close to the time when an integer value of the minimum in q is crossed. While this phenomenon has been observed on many tokamaks, the extensive transport and fluctuation diagnostics on DIII-D have permitted a detailed study of the generation mechanisms of q-triggered ITBs as pertaining to turbulence suppression dynamics, shear flows, and energetic particle modes. In these discharges, the evolution of the q profile is measured using motional Stark effect polarimetry and the integer q min crossings are further pinpointed in time by the observation of Alfven cascades. High time resolution measurements of the ion and electron temperatures and the toroidal rotation show that the start of improved confinement is simultaneous in all three channels, and that this event precedes the traversal of integer q min by 5-20 ms. There is no significant low-frequency magnetohydrodynamic activity prior to or just after the crossing of the integer q min and hence magnetic reconnection is determined not to be the precipitant of the confinement change. Instead, results from the GYRO code point to the effects of zonal flows near low order rational q values as playing a role in ITB triggering. A reduction in local turbulent fluctuations is observed at the start of the temperature rise and, concurrently, an increase in turbulence poloidal flow velocity and flow shear is measured with the beam emission spectroscopy diagnostic. For the case of a transition to an enduring internal barrier the fluctuation level remains at a reduced amplitude. The timing and nature of the temperature, rotation, and fluctuation changes leading to internal barriers suggests transport improvement due to increased shear flow arising from the zonal flow structures

  11. Nested Inversion Polymorphisms Predispose Chromosome 22q11.2 to Meiotic Rearrangements

    NARCIS (Netherlands)

    Demaerel, Wolfram; Hestand, Matthew S.; Vergaelen, Elfi; Swillen, Ann; López-Sánchez, Marcos; Pérez-Jurado, Luis A.; McDonald-Mcginn, Donna M.; Zackai, Elaine; Emanuel, Beverly S.; Morrow, Bernice E.; Breckpot, Jeroen; Devriendt, Koenraad; Vermeesch, Joris R.; Antshel, Kevin M.; Arango, Celso; Armando, Marco; Bassett, Anne S.; Bearden, Carrie E.; Boot, Erik; Bravo-Sanchez, Marta; Breetvelt, Elemi; Busa, Tiffany; Butcher, Nancy J.; Campbell, Linda E.; Carmel, Miri; Chow, Eva W C; Crowley, T. Blaine; Cubells, Joseph; Cutler, David; Demaerel, Wolfram; Digilio, Maria Cristina; Duijff, Sasja; Eliez, Stephan; Emanuel, Beverly S.; Epstein, Michael P.; Evers, Rens; Fernandez Garcia-Moya, Luis; Fiksinski, Ania; Fraguas, David; Fremont, Wanda; Fritsch, Rosemarie; Garcia-Minaur, Sixto; Golden, Aaron; Gothelf, Doron; Guo, Tingwei; Gur, Ruben C.; Gur, Raquel E.; Heine-Suner, Damian; Hestand, Matthew; Hooper, Stephen R.; Kates, Wendy R.; Kushan, Leila; Laorden-Nieto, Alejandra; Maeder, Johanna; Marino, Bruno; Marshall, Christian R.; McCabe, Kathryn; McDonald-Mcginn, Donna M.; Michaelovosky, Elena; Morrow, Bernice E.; Moss, Edward; Mulle, Jennifer; Murphy, Declan; Murphy, Kieran C.; Murphy, Clodagh M.; Niarchou, Maria; Ornstein, Claudia; Owen, Michael J; Philip, Nicole; Repetto, Gabriela M.; Schneider, Maude; Shashi, Vandana; Simon, Tony J.; Swillen, Ann; Tassone, Flora; Unolt, Marta; Van Amelsvoort, Therese; van den Bree, Marianne B M; Van Duin, Esther; Vergaelen, Elfi; Vermeesch, Joris R.; Vicari, Stefano; Vingerhoets, Claudia; Vorstman, Jacob; Warren, Steve; Weinberger, Ronnie; Weisman, Omri; Weizman, Abraham; Zackai, Elaine; Zhang, Zhengdong; Zwick, Michael

    2017-01-01

    Inversion polymorphisms between low-copy repeats (LCRs) might predispose chromosomes to meiotic non-allelic homologous recombination (NAHR) events and thus lead to genomic disorders. However, for the 22q11.2 deletion syndrome (22q11.2DS), the most common genomic disorder, no such inversions have

  12. Genetic Algorithm Optimizes Q-LAW Control Parameters

    Science.gov (United States)

    Lee, Seungwon; von Allmen, Paul; Petropoulos, Anastassios; Terrile, Richard

    2008-01-01

    A document discusses a multi-objective, genetic algorithm designed to optimize Lyapunov feedback control law (Q-law) parameters in order to efficiently find Pareto-optimal solutions for low-thrust trajectories for electronic propulsion systems. These would be propellant-optimal solutions for a given flight time, or flight time optimal solutions for a given propellant requirement. The approximate solutions are used as good initial solutions for high-fidelity optimization tools. When the good initial solutions are used, the high-fidelity optimization tools quickly converge to a locally optimal solution near the initial solution. Q-law control parameters are represented as real-valued genes in the genetic algorithm. The performances of the Q-law control parameters are evaluated in the multi-objective space (flight time vs. propellant mass) and sorted by the non-dominated sorting method that assigns a better fitness value to the solutions that are dominated by a fewer number of other solutions. With the ranking result, the genetic algorithm encourages the solutions with higher fitness values to participate in the reproduction process, improving the solutions in the evolution process. The population of solutions converges to the Pareto front that is permitted within the Q-law control parameter space.

  13. IceCube potential for detecting Q-ball dark matter in gauge mediation

    International Nuclear Information System (INIS)

    Kasuya, Shinta; Kawasaki, Masahiro; Yanagida, Tsutomu T.

    2015-01-01

    We study Q-ball dark matter in gauge-mediated supersymmetry breaking, and seek the possibility of detection in the IceCube experiment. We find that the Q balls would be the dark matter in the parameter region different from that for gravitino dark matter. In particular, the Q ball is a good dark matter candidate for low reheating temperature, which may be suitable for the Affleck–Dine baryogenesis and/or nonthermal leptogenesis. Dark matter Q balls are detectable by IceCube-like experiments in the future, which is a peculiar feature compared to the case of gravitino dark matter

  14. A measurement of the proton’s spin structure function g2 at low Q2

    Energy Technology Data Exchange (ETDEWEB)

    Zhu, Pengjia [Univ. of Science and Technology of China, Hefei (China)

    2015-10-21

    JLab E08-027, a measurement of g2p and the longitudinal-transverse (LT) spin polarizability, successfully collected data from March to May, 2012. Nucleon spin structure study has been an active research area, which has attracted a very large effort from both experimentalists and theorists. The spin structure study for the last 2 decades has provided us with many exciting and often surprising results. Recently, new precision results in the low-to-intermediate momentum transfer Q2 region from JLab have provided extensive information on the nucleon structure in the confinement region and the transition region between asymptotic free to confinement. In particular, the extensive comparisons of experimental results with Chiral Perturbation Theory (the effective theory of QCD at low energy) calculations show general good agreements, but strong disagreement in the case of the neutron LT spin polarizability. This experiment completed the measurements of gp2 and the LT spin polarizability on the proton in the low-to-intermediate Q2 region. The experiment used a polarized proton (NH3) target for the first time in Hall A. Scattered electrons were detected by a pair of Hall A high resolution spectrometer (HRS) with a pair of septum magnets. To avoid too much depolarization of the target, beam current was limited to 50-100 nA during the experiment. Since the existing beam current monitors (BCMs), beam position monitors (BPMs) and calibration methods did not work at such a low current range, new BPM and BCM receivers were designed and used for current condition. A pair of super-harps and a tungsten calorimeter were installed to calibrate the BPMs and BCMs. To compensate for the effect of the 2.5/5T transverse magnet field, two chicane dipole magnets were installed. A pair of slow rasters were installed for the first time in Hall A, combining with a pair of fast raster. The standard Hall A DAQ system and the improved high resolution DAQ system were used to record the detector

  15. Clinical delineation of a patient with trisomy 12q23q24

    NARCIS (Netherlands)

    Bouman, Arjan; Schuitema, Anke; Pfundt, Rolph; van de Zande, Guillaume; Kleefstra, Tjitske

    2013-01-01

    Trisomies of 12q23q24 have been described rarely in literature. Only a few case-reports have been published so far almost exclusively reporting on neonates or young infants. We present a 16-year-old patient with a trisomy of 12q23.3q24.3. Full phenotypic evaluation at this age comprised: severe

  16. A survey of tools for the analysis of quantitative PCR (qPCR data

    Directory of Open Access Journals (Sweden)

    Stephan Pabinger

    2014-09-01

    Our comprehensive survey showed that most tools use their own file format and only a fraction of the currently existing tools support the standardized data exchange format RDML. To allow a more streamlined and comparable analysis of qPCR data, more vendors and tools need to adapt the standardized format to encourage the exchange of data between instrument software, analysis tools, and researchers.

  17. The HIA instrument on board the Tan Ce 1 Double Star near-equatorial spacecraft and its first results

    Directory of Open Access Journals (Sweden)

    H. Rème

    2005-11-01

    Full Text Available On 29 December 2003, the Chinese spacecraft Tan Ce 1 (TC-1, the first component of the Double Star mission, was successfully launched within a low-latitude eccentric orbit. In the framework of the scientific cooperation between the Academy of Sciences of China and ESA, several European instruments, identical to those developed for the Cluster spacecraft, were installed on board this spacecraft. The HIA (Hot Ion Analyzer instrument on board the TC-1 spacecraft is an ion spectrometer nearly identical to the HIA sensor of the CIS instrument on board the 4 Cluster spacecraft. This instrument has been specially adapted for TC-1. It measures the 3-D distribution functions of the ions between 5 eV/q and 32 keV/q without mass discrimination. TC-1 is like a fifth Cluster spacecraft to study the interaction of the solar wind with the magnetosphere and to study geomagnetic storms and magnetospheric substorms in the near equatorial plane. HIA was commissioned in February 2004. Due to the 2 RE higher apogee than expected, some in-flight improvements were needed in order to use HIA in the solar wind in the initial phase of the mission. Since this period HIA has obtained very good measurements in the solar wind, the magnetosheath, the dayside and nightside plasma sheet, the ring current and the radiation belts. We present here the first results in the different regions of the magnetosphere and in the solar wind. Some of them are very new and include, for example, ion dispersion structures in the bow shock and ion beams close to the magnetopause. The huge interest in the orbit of TC-1 is strongly demonstrated.

  18. The HIA instrument on board the Tan Ce 1 Double Star near-equatorial spacecraft and its first results

    Directory of Open Access Journals (Sweden)

    H. Rème

    2005-11-01

    Full Text Available On 29 December 2003, the Chinese spacecraft Tan Ce 1 (TC-1, the first component of the Double Star mission, was successfully launched within a low-latitude eccentric orbit. In the framework of the scientific cooperation between the Academy of Sciences of China and ESA, several European instruments, identical to those developed for the Cluster spacecraft, were installed on board this spacecraft.

    The HIA (Hot Ion Analyzer instrument on board the TC-1 spacecraft is an ion spectrometer nearly identical to the HIA sensor of the CIS instrument on board the 4 Cluster spacecraft. This instrument has been specially adapted for TC-1. It measures the 3-D distribution functions of the ions between 5 eV/q and 32 keV/q without mass discrimination.

    TC-1 is like a fifth Cluster spacecraft to study the interaction of the solar wind with the magnetosphere and to study geomagnetic storms and magnetospheric substorms in the near equatorial plane.

    HIA was commissioned in February 2004. Due to the 2 RE higher apogee than expected, some in-flight improvements were needed in order to use HIA in the solar wind in the initial phase of the mission. Since this period HIA has obtained very good measurements in the solar wind, the magnetosheath, the dayside and nightside plasma sheet, the ring current and the radiation belts. We present here the first results in the different regions of the magnetosphere and in the solar wind. Some of them are very new and include, for example, ion dispersion structures in the bow shock and ion beams close to the magnetopause. The huge interest in the orbit of TC-1 is strongly demonstrated.

  19. A survey of tools for the analysis of quantitative PCR (qPCR) data.

    Science.gov (United States)

    Pabinger, Stephan; Rödiger, Stefan; Kriegner, Albert; Vierlinger, Klemens; Weinhäusel, Andreas

    2014-09-01

    Real-time quantitative polymerase-chain-reaction (qPCR) is a standard technique in most laboratories used for various applications in basic research. Analysis of qPCR data is a crucial part of the entire experiment, which has led to the development of a plethora of methods. The released tools either cover specific parts of the workflow or provide complete analysis solutions. Here, we surveyed 27 open-access software packages and tools for the analysis of qPCR data. The survey includes 8 Microsoft Windows, 5 web-based, 9 R-based and 5 tools from other platforms. Reviewed packages and tools support the analysis of different qPCR applications, such as RNA quantification, DNA methylation, genotyping, identification of copy number variations, and digital PCR. We report an overview of the functionality, features and specific requirements of the individual software tools, such as data exchange formats, availability of a graphical user interface, included procedures for graphical data presentation, and offered statistical methods. In addition, we provide an overview about quantification strategies, and report various applications of qPCR. Our comprehensive survey showed that most tools use their own file format and only a fraction of the currently existing tools support the standardized data exchange format RDML. To allow a more streamlined and comparable analysis of qPCR data, more vendors and tools need to adapt the standardized format to encourage the exchange of data between instrument software, analysis tools, and researchers.

  20. A q-Schroedinger algebra, its lowest weight representations and generalized q-deformed heat equations

    International Nuclear Information System (INIS)

    Dobrev, V.K.; Doebner, H.D.; Mrugalla, C.

    1995-12-01

    We give a q-deformation S-perpendicular q of the centrally extended Schroedinger algebra. We construct the lowest weight representations of S-perpendicular q , starting from the Verma modules over S-perpendicular q , finding their singular vectors and factoring the Verma submodules built on the singular vectors. We also give a vector-field realization of S-perpendicular q which provides polynomial realization of the lowest weight representations and an infinite hierarchy of q-difference equations which may be called generalized q-deformed heat equations. We also apply our methods to the on-shell q-Schroedinger algebra proposed by Floreanini and Vinet. (author). 12 refs

  1. Weyl q-coefficients for uq(3) and Racah q -coefficients for suq(2)

    International Nuclear Information System (INIS)

    Asherova, R.M.; Smirnov, Yu.F.; Tolstoy, V.N.

    1996-01-01

    With the aid of the projection-operator technique, the general analytic expression for the elements of the matrix that relates the U and T bases of an arbitrary finite-dimensional irreducible representation of the uq(3) quantum algebra (Weyl q-coefficients) is obtained for the case where the deformation parameter q is not equal to a square root of unity. The procedure for resummation of q-factorial expressions is used to prove that, modulo phase factors, these Weyl q-coefficients coincide with Racah q-coefficients for the suq(2) quantum algebra. It is also shown that, on the basis of one general formula, the q-analogs of all known general analytic expressions for the 6j symbols (and Racah coefficients) of the Lie algebras of the angular momentum can be obtained by using this resummation procedure. The symmetry properties of these q coefficients are discussed. The result is formulated in the following way: the general formulas for the q-6j symbols (Racah q-coefficients) of the suq(2) quantum algebra are obtained from the general formulas for the conventional 6j symbols (Racah coefficients) of the su(2) Lie algebra by replacing directly all factorials with q-factorials, the symmetry properties of the q-6j symbols being completely coincident with the symmetry properties of the conventional 6j symbols

  2. De novo microdeletions of chromosome 6q14.1-q14.3 and 6q12.1-q14.1 in two patients with intellectual disability - further delineation of the 6q14 microdeletion syndrome and review of the literature

    DEFF Research Database (Denmark)

    Becker, Kerstin; Di Donato, Nataliya; Holder-Espinasse, Muriel

    2012-01-01

    with broad nasal tip, anteverted nares, long philtrum, and thin upper lip. In this study we describe two patients with overlapping 6q14 deletions presenting with developmental delay and characteristic dysmorphism. Molecular karyotyping using array CGH analysis revealed a de novo 8.9 Mb deletion at 6q14.1-q14.......3 and a de novo 11.3 Mb deletion at 6q12.1-6q14.1, respectively. We provide a review of the clinical features of twelve other patients with 6q14 deletions detected by array CGH analysis. By assessing all reported data we could not identify a single common region of deletion. Possible candidate genes in 6q14...

  3. $q$-norms are really norms

    OpenAIRE

    Belbachir, H.; Mirzavaziri, M.; Moslehian, M. S.

    2005-01-01

    Replacing the triangle inequality, in the definition of a norm, by $|x + y| ^{q}\\leq 2^{q-1}(|x| ^{q} + |y| ^{q}) $, we introduce the notion of a q-norm. We establish that every q-norm is a norm in the usual sense, and that the converse is true as well.

  4. QqZ decays at Tevatron and SSC energies

    International Nuclear Information System (INIS)

    Agrawal, P.; Ellis, S.D.

    1990-09-01

    The possible existence of a new heavy quark Q that decays predominantly via the flavor changing neutral current transition QqZ is discussed. Candidates include a fourth generation charge -- 1/3 quark, or a more exotic vector-like quark. Such particles are interesting both as extensions of the Standard Model and due to their unique decay modes. The primary experimental indication of the pair production and subsequent decay of quarks is ZZ pair production at an essentially strong interaction rate. This mode can then constitute an unexpected background to the searches for other particles. In particular the channel Q bar Q → ZZ + X can generate a serious background to the search for the Higgs boson via the H 0 → ZZ mode at the SSC. Thus it is essential to search for such new heavy quarks at the Tevatron. Possible detection signatures for this purpose are discussed. 24 refs. , 1 fig., 3 tabs

  5. 18q- and 18q+ mosaicism in a mentally retarded boy

    NARCIS (Netherlands)

    Ausems, M. G.; Bhola, S. L.; Post-Blok, C. A.; Hennekam, R. C.; de France, H. F.

    1994-01-01

    A mentally retarded boy was found to have an unusual chromosomal mosaicism [46,XY, del(18) (q22)/46,XY,iso psu dic(18)(q23)]. The clinical manifestations are compatible with the 18q- syndrome. The chromosome alteration was defined by high resolution banding and fluorescence in situ hybridization

  6. Q and you: The application of Q methodology in recreation research

    Science.gov (United States)

    Whitney. Ward

    2010-01-01

    Researchers have used various qualitative and quantitative methods to deal with subjectivity in studying people's recreation experiences. Q methodology has been the most effective approach for analyzing both qualitative and quantitative aspects of experience, including attitudes or perceptions. The method is composed of two main components--Q sorting and Q factor...

  7. DOSIMETRIC response of a REM-500 in low energy neutron fields typical of nuclear power plants.

    Science.gov (United States)

    Aslam; Matysiak, W; Atanackovic, J; Waker, A J

    2012-06-01

    This study investigates the response of a REM-500 to assess neutron quality factor and dose equivalent in low energy neutron fields, which are commonly encountered in the workplace environment of nuclear power stations. The McMaster University 3 MV Van de Graaff accelerator facility was used to measure the response of the instrument in monoenergetic neutron fields in the energy range 51 to 727 keV by bombarding a thin LiF target with 1.93-2.50 MeV protons. The energy distribution of the neutron fields produced in the facility was measured by a (3)He filled gas ionization chamber. The MCA mode of the REM-500 instrument was used to collect lineal energy distributions at varying neutron energies and to calculate the frequency and dose-mean lineal energies. The effective quality factor, Q-, was also calculated using the values of Q(y)listed in the REM-500 operation manual and compared with those of ICRP 60. The authors observed a continuously increasing trend in y - F, y-D, and Q-with an increase in neutron energy. It is interesting to note that standard tissue equivalent proportional counters (TEPCs) filled with tissue equivalent(TE) gas give rise to a similar trend for these microdosimetric quantities of interest in the same energy range; however, the averages calculated in this study are larger by about 15%compared to a TEPC filled with propane-based TE gas probably because of the larger stopping power of protons in propane compared to TE gas. These somewhat larger event sizes did not result in any significant increase in the Q-compared to those obtained from a TEPC filled with TE gas and were found to be in good agreement with other measurements reported earlier at corresponding neutron energies. The instrument quality factor response, R(Q), defined as the ratio of measured quality factor to the calculated quality factor in an ICRU tissue sphere,was found to vary with neutron energy. The instrument response,R(Q), was ~0.6 at 727 keV, which deteriorates further to

  8. A case of de novo duplication of 15q24-q26.3

    Directory of Open Access Journals (Sweden)

    Hye Ran Kim

    2011-06-01

    Full Text Available Distal duplication, or trisomy 15q, is an extremely rare chromosomal disorder characterized by prenatal and postnatal overgrowth, mental retardation, and craniofacial malformations. Additional abnormalities typically include an unusually short neck, malformations of the fingers and toes, scoliosis and skeletal malformations, genital abnormalities, particularly in affected males, and, in some cases, cardiac defects. The range and severity of symptoms and physical findings may vary from case to case, depending upon the length and location of the duplicated portion of chromosome 15q. Most reported cases of duplication of the long arm of chromosome 15 frequently have more than one segmental imbalance resulting from unbalanced translocations involving chromosome 15 and deletions in another chromosome, as well as other structural chromosomal abnormalities. We report a female newborn with a de novo duplication, 15q24- q26.3, showing intrauterine overgrowth, a narrow asymmetric face with down-slanting palpebral fissures, a large, prominent nose, and micrognathia, arachnodactyly, camptodactyly, congenital heart disease, hydronephrosis, and hydroureter. Chromosomal analysis showed a 46,XX,inv(9(p12q13,dup(15(q24q26.3. Array comparative genomic hybridization analysis revealed a gain of 42 clones on 15q24-q26.3. This case represents the only reported patient with a de novo 15q24-q26.3 duplication that did not result from an unbalanced translocation and did not have a concomitant monosomic component in Korea.

  9. Compact, passively Q-switched Nd:YAG laser for the MESSENGER mission to Mercury.

    Science.gov (United States)

    Krebs, Danny J; Novo-Gradac, Anne-Marie; Li, Steven X; Lindauer, Steven J; Afzal, Robert S; Yu, Anthony W

    2005-03-20

    A compact, passively Q-switched Nd:YAG laser has been developed for the Mercury Laser Altimeter, an instrument on the Mercury Surface, Space Environment, Geochemistry, and Ranging mission to the planet Mercury. The laser achieves 5.4% efficiency with a near-diffraction-limited beam. It passed all space-flight environmental tests at subsystem, instrument, and satellite integration testing and successfully completes a postlaunch aliveness check en route to Mercury. The laser design draws on a heritage of previous laser altimetry missions, specifically the Ice Cloud and Elevation Satellite and the Mars Global Surveyor, but incorporates thermal management features unique to the requirements of an orbit of the planet Mercury.

  10. Q-instantons

    NARCIS (Netherlands)

    Bergshoeff, E. A.; Hartong, J.; Ploegh, A.; Sorokin, D.

    We construct the half-supersymmetric instanton solutions that are electric-magnetically dual to the recently discussed half-supersymmetric Q7-branes. We call these instantons "Q-instantons". Whereas the D-instanton is most conveniently described using the RR axion chi and the dilaton phi, the

  11. Structural and electronic properties of Cu2Q and CuQ (Q = O, S, Se, and Te) studied by first-principles calculations

    Science.gov (United States)

    Zhao, Ting; Wang, Yu-An; Zhao, Zong-Yan; Liu, Qiang; Liu, Qing-Ju

    2018-01-01

    In order to explore the similarity, difference, and tendency of binary copper-based chalcogenides, the crystal structure, electronic structure, and optical properties of eight compounds of Cu2Q and CuQ (Q = O, S, Se, and Te) have been calculated by density functional theory with HSE06 method. According to the calculated results, the electronic structure and optical properties of Cu2Q and CuQ present certain similarities and tendencies, with the increase of atomic number of Q elements: the interactions between Cu-Q, Cu-Cu, and Q-Q are gradually enhancing; the value of band gap is gradually decreasing, due to the down-shifting of Cu-4p states; the covalent feature of Cu atoms is gradually strengthening, while their ionic feature is gradually weakening; the absorption coefficient in the visible-light region is also increasing. On the other hand, some differences can be found, owing to the different crystal structure and component, for example: CuO presents the characteristics of multi-band gap, which is very favorable to absorb infrared-light; the electron transfer in CuQ is stronger than that in Cu2Q; the absorption peaks and intensity are very strong in the ultraviolet-light region and infrared-light region. The findings in the present work will help to understand the underlying physical mechanism of binary copper-based chalcogenides, and available to design novel copper-based chalcogenides photo-electronics materials and devices.

  12. 78 FR 65698 - Notice of Availability of the Final Environmental Impact Statement for the Gas Hills In Situ...

    Science.gov (United States)

    2013-11-01

    ... production areas, or mine units, with subsurface ore bodies within the Wind River Formation for ISR extraction. Construction, operation, groundwater restoration, and surface reclamation of five mine units... Department of Environmental Quality Land Quality Division's (WDEQ-LQD) Mine Permit Application 687. In...

  13. Chemical failure modes of AlQ3-based OLEDs: AlQ3 hydrolysis.

    Science.gov (United States)

    Knox, John E; Halls, Mathew D; Hratchian, Hrant P; Schlegel, H Bernhard

    2006-03-28

    Tris(8-hydroxyquinoline)aluminum(III), AlQ3, is used in organic light-emitting diodes (OLEDs) as an electron-transport material and emitting layer. The reaction of AlQ3 with trace H2O has been implicated as a major failure pathway for AlQ3-based OLEDs. Hybrid density functional calculations have been carried out to characterize the hydrolysis of AlQ3. The thermochemical and atomistic details for this important reaction are reported for both the neutral and oxidized AlQ3/AlQ3+ systems. In support of experimental conclusions, the neutral hydrolysis reaction pathway is found to be a thermally activated process, having a classical barrier height of 24.2 kcal mol(-1). First-principles infrared and electronic absorption spectra are compared to further characterize AlQ3 and the hydrolysis pathway product, AlQ2OH. The activation energy for the cationic AlQ3 hydrolysis pathway is found to be 8.5 kcal mol(-1) lower than for the neutral reaction, which is significant since it suggests a role for charge imbalance in promoting chemical failure modes in OLED devices.

  14. Various endocrine disorders in children with t(13;14(q10;q10 Robertsonian translocation

    Directory of Open Access Journals (Sweden)

    Byung Ho Choi

    2013-09-01

    Full Text Available Purpose45,XY,t(13;14(q10;q10 karyotype can suggest infertility associated with more or less severe oligospermia in male adults. In addition, 45,XX,t(13;14(q10;q10 karyotype carries reproductive risks such as miscarriage or infertility in female adults. However, reports on the phenotype of this karyotype in children are very rare. This study was done to observe various phenotypes of this karyotype in children.MethodsBetween January 2007 and December 2012, children diagnosed with 45,XY,t(13;14(q10;q10 or 45,XX,t(13;14(q10;q10 karyotype by chromosome analysis were analyzed retrospectively.ResultsEight children (5 boys and 3 girls were diagnosed with 45,XY,t(13;14(q10;q10 or 45,XX,t(13;14(q10;q10 karyotype. They ranged in age from 5 years and 6 months to 12 years and 4 months. The phenotypes of the study patients consisted of 1 hypogonadotrophic hypogonadism, 1 precocious puberty, 3 early puberty, 2 growth hormone deficiency (GHD (partial and 1 idiopathic short stature. As shown here t(13;14(q10;q10 Robertsonian translocation shows a wide range of phenotypes.ConclusionIt can be said that t(13;14(q10;q10 Robertsonian translocation shows various phenotypes from GHD to precocious puberty in children. Further large-scale studies are necessary.

  15. Immunomodulatory effects of L-carnitine and q10 in mouse spleen exposed to low-frequency high-intensity magnetic field

    International Nuclear Information System (INIS)

    Arafa, Hossam M.M.; Abd-Allah, Adel R.A.; El-Mahdy, Mohamad A.; Ramadan, Laila A.; Hamada, Farid M.A.

    2003-01-01

    In the current study, we have investigated the bioeffects of repeated exposure to low-frequency (50 Hz) high-intensity (20 mT; 200 G) electromagnetic field (EMF) on some immune parameters in mice. The animals were exposed to EMF daily for 30 min three times per week for 2 weeks. We also studied the possible immunomodulatory effects of two anti-radical substances known to have non-specific immunostimulant effects namely, L-carnitine (200 mg/kg body weight i.p.) and Q10 (200 mg/kg body weight, p.o.). Both drugs were given 1 h prior to each EMF exposure. Immune endpoints included total body weight, spleen/body weight ratio, splenocytes viability, total and differential white blood cell (WBCs; lymphocytes, monocytes, neutrophils) counts, as well as the lymphocyte proliferation induced by the mitogens; phytohaemagglutinin (PHA), concanavalin-A (Con-A) and lipoploysaccharide (LPS). Magnetic field decreased splenocyte viability, WBCs count, as well as mitogens-induced lymphocyte proliferation. L-carnitine, but not Q10 could ameliorate the adverse effects of EMF on the vast majority of the immune parameters tested, suggesting a possible immunoprotective role of L-carnitine under the current experimental conditions

  16. Q2/Q3 2017 Solar Industry Update

    Energy Technology Data Exchange (ETDEWEB)

    Feldman, David J. [National Renewable Energy Lab. (NREL), Golden, CO (United States); Hoskins, Jack [Dept. of Energy (DOE), Washington DC (United States); Margolis, Robert M. [National Renewable Energy Lab. (NREL), Golden, CO (United States)

    2017-10-24

    This technical presentation provides an update on the major trends that occurred in the solar industry in Q2 and Q3 of 2017. Major topics of focus include global and U.S. supply and demand, module and system price, investment trends and business models, and updates on U.S. government programs supporting the solar industry.

  17. Q2/Q3 2016 Solar Industry Update

    Energy Technology Data Exchange (ETDEWEB)

    Feldman, David; Boff, Daniel; Margolis, Robert

    2016-10-11

    This technical presentation provides an update on the major trends that occurred in the solar industry in the Q2 and Q3 of 2016. Major topics of focus include global and U.S. supply and demand, module and system price, investment trends and business models, and updates on U.S. government programs supporting the solar industry.

  18. Q3/Q4 2016 Solar Industry Update

    Energy Technology Data Exchange (ETDEWEB)

    Feldman, David; Boff, Daniel; Margolis, Robert

    2016-12-21

    This technical presentation provides an update on the major trends that occurred in the solar industry in the Q3 and Q4 of 2016. Major topics of focus include global and U.S. supply and demand, module and system price, investment trends and business models, and updates on U.S. government programs supporting the solar industry.

  19. Q3/Q4 2017 Solar Industry Update

    Energy Technology Data Exchange (ETDEWEB)

    Feldman, David J. [National Renewable Energy Lab. (NREL), Golden, CO (United States); Hoskins, Jack [Dept. of Energy (DOE), Washington DC (United States); Margolis, Robert M. [National Renewable Energy Lab. (NREL), Golden, CO (United States)

    2018-02-15

    This technical presentation provides an update on the major trends that occurred in the solar industry in the Q3 and Q4 of 2017. Major topics of focus include global and U.S. supply and demand, module and system price, investment trends and business models, and updates on U.S. government programs supporting the solar industry.

  20. Further validation of the Motivation for Traumatic Brain Injury Rehabilitation Questionnaire (MOT-Q) in patients with acquired brain injury.

    Science.gov (United States)

    Boosman, Hileen; van Heugten, Caroline M; Winkens, Ieke; Smeets, Sanne M J; Visser-Meily, Johanna M A

    2016-01-01

    The Motivation for Traumatic Brain Injury Rehabilitation Questionnaire (MOT-Q) evaluates motivation for rehabilitation in four subscales: Interest in rehabilitation, Lack of anger, Lack of denial, and Reliance on professional help. The objective of this study was to further validate the MOT-Q in 122 inpatients and 92 outpatients with acquired brain injury (ABI). The main measures were motivation for rehabilitation (MOT-Q), self-awareness (Patient Competency Rating Scale), and treatment motivation (Visual Analogue Scale). The MOT-Q showed adequate feasibility in terms of few items with missing responses and few undecided responses. We found no floor or ceiling effects, and significant item-total MOT-Q correlations for 29 of 31 items. Internal consistency was good for the MOT-Q total and acceptable to good for the subscales. The MOT-Q scores were significantly intercorrelated except for the subscales Lack of denial and Reliance on professional help in the inpatient group. The MOT-Q total and subscales were significantly associated with treatment motivation. The Lack of denial subscale showed no significant association with treatment motivation and no to moderate significant associations with self-awareness. In conclusion, the overall MOT-Q is a valid instrument to assess motivation for rehabilitation in patients with ABI. Further research is needed to examine the validity of the subscales.

  1. Search for copy number variants in chromosomes 15q11-q13 and 22q11.2 in obsessive compulsive disorder

    Directory of Open Access Journals (Sweden)

    Grabe Hans

    2010-06-01

    Full Text Available Abstract Background Obsessive-compulsive disorder (OCD is a clinically and etiologically heterogeneous syndrome. The high frequency of obsessive-compulsive symptoms reported in subjects with the 22q11.2 deletion syndrome (DiGeorge/velocardiofacial syndrome or Prader-Willi syndrome (15q11-13 deletion of the paternally derived chromosome, suggests that gene dosage effects in these chromosomal regions could increase risk for OCD. Therefore, the aim of this study was to search for microrearrangements in these two regions in OCD patients. Methods We screened the 15q11-13 and 22q11.2 chromosomal regions for genomic imbalances in 236 patients with OCD using multiplex ligation-dependent probe amplification (MLPA. Results No deletions or duplications involving 15q11-13 or 22q11.2 were identified in our patients. Conclusions Our results suggest that deletions/duplications of chromosomes 15q11-13 and 22q11.2 are rare in OCD. Despite the negative findings in these two regions, the search for copy number variants in OCD using genome-wide array-based methods is a highly promising approach to identify genes of etiologic importance in the development of OCD.

  2. Application of the correction factor for radiation qualityK{sub q} in dosimetry with pencil-type ionization chambers using a Tandem system

    Energy Technology Data Exchange (ETDEWEB)

    Fontes, Ladyjane Pereira; Potiens, Maria da Penha Albuquerque, E-mail: lpfontes@ipen.br [Instituto de Pesquisas Energeticas e Nucleares (IPEN/CNEN-SP), Sao Paulo, SP (Brazil)

    2017-11-01

    The pencil-type ionization chamber widely used in computed tomography (CT) dosimetry, is a measuring instrument that has a cylindrical shape and provides uniform response independent of the angle of incidence of ionizing radiation. Calibration and measurements performed with the pencil-type ionization chamber are done in terms of Kerma product in air-length (P{sub k,l}) and values are given in Gy.cm. To obtain the values of (P{sub k,l}) during clinical measurements, the readings performed with the ionization chamber are multiplied by the calibration coefficient (N{sub k,l}) and the correction factor C for quality (K{sub q}) which are given in Calibration certificates of the chambers. The application of the correction factor for radiation quality K{sub q} is done as a function of the effective energy of the beam that is determined by the Half Value layer (HVL) calculation. In order to estimate the HVL values in this work, a Tandem system made up of cylindrical aluminum and PMMA absorber layers was used as a low cost and easy to apply method. From the Tandem curve, it was possible to construct the calibration curve and obtain the appropriate K{sub q} to the beam of the computed tomography equipment studied. (author)

  3. Nanosecond Q-switched operation of coupled Yb and Tm fibre lasers

    Energy Technology Data Exchange (ETDEWEB)

    Tsang, Yuen H [Laser Photonics Research Group, School of Physics and Astronomy, University of Manchester, Manchester M13 9PL (United Kingdom); Qamar, Fadi [Laser Photonics Research Group, School of Physics and Astronomy, University of Manchester, Manchester M13 9PL (United Kingdom); King, Terence A [Laser Photonics Research Group, School of Physics and Astronomy, University of Manchester, Manchester M13 9PL (United Kingdom); Ko, Do-Kyeong [Advanced Photonics Research Institute, Gwangju Institute of Science and Technology, 1 Oryong-dong, Buk-Gu, Gwangju 500-712 (Korea, Republic of); Lee, Jongmin [Advanced Photonics Research Institute, Gwangju Institute of Science and Technology, 1 Oryong-dong, Buk-Gu, Gwangju 500-712 (Korea, Republic of)

    2005-05-07

    A small scale coupled Yb-silica and Tm-silica fibre laser system is described with output at 1.9 {mu}m and with Q-switching using an acousto-optic modulator and also by mechanical optical modulation. The Yb-fibre laser pump source exhibited strong self-pulsation with high-intensity pulses due to stimulated Brillouin scattering. But regular Q-switched pulses were generated from the Tm-fibre laser with an energy of {approx}2.4 {mu}J and duration (FWHM) of {approx}280 ns for modulation frequencies of 1-20 kHz when using acousto-optic modulation. The main effects that limit the Q-switched pulse peak power are the onset of gain-switched pulsing during the low-Q state and strong pump excited state absorption.

  4. Trisomy 1q42-qter associated with monosomy 6q27-qter: a case report.

    Science.gov (United States)

    Tartaglia, Edoardo; Mastrantonio, Pasquale; Costa, Davide; Giugliano, Brunella; Porcellini, Antonio; Costagliola, Ciro

    2011-01-01

    Partial trisomy 1q42-qter is a rare chromosomal aberration. Most cases arise from de novo unbalanced translocations or from unbalanced inheritance of parental balanced rearrangements. Descriptive case report. A 4-year-old boy had shown an increased neck translucency at the fetal ultrasound examination performed at the 11th week of gestation. Amniocentesis, performed at the 18th week of gestation, did not demonstrate any genetic abnormality. A second fetal ultrasound examination, carried out at the 35th week of gestation, showed congenital clubfeet and hydrocephalus. At birth, clinical examination revealed congenital bilateral ventriculomegaly, bilateral congenital equinovarus clubfeet, low-set ears, plagiocephaly, micrognathia, hypertelorism, prominent forehead, broad nasal bridge, hypertonic syndrome, and inguinal hernia. Ophthalmologic consultation showed the presence of optic pit in his left eye. Genetic counseling was performed. Chromosome analysis demonstrated a partial trisomy 1q42.2-qter associated with a partial monosomy 6q27-qter. Moreover, deletions of the distal region on the long arm of chromosome 6 are frequently associated with both ocular abnormalities and several solid tumor types. Moderate mental and psychomotor retardation has occurred. This case emphasizes the importance of scheduling a screening test for eye diseases and tumor in these patients.

  5. Q selection for an electro-optical earth imaging system: theoretical and experimental results.

    Science.gov (United States)

    Cochrane, Andy; Schulz, Kevin; Kendrick, Rick; Bell, Ray

    2013-09-23

    This paper explores practical design considerations for selecting Q for an electro-optical earth imaging system, where Q is defined as (λ FN) / pixel pitch. Analytical methods are used to show that, under imaging conditions with high SNR, increasing Q with fixed aperture cannot lead to degradation of image quality regardless of the angular smear rate of the system. The potential for degradation of image quality under low SNR is bounded by an increase of the detector noise scaling as Q. An imaging test bed is used to collect representative imagery for various Q configurations. The test bed includes real world errors such as image smear and haze. The value of Q is varied by changing the focal length of the imaging system. Imagery is presented over a broad range of parameters.

  6. The q-G method : A q-version of the Steepest Descent method for global optimization.

    Science.gov (United States)

    Soterroni, Aline C; Galski, Roberto L; Scarabello, Marluce C; Ramos, Fernando M

    2015-01-01

    In this work, the q-Gradient (q-G) method, a q-version of the Steepest Descent method, is presented. The main idea behind the q-G method is the use of the negative of the q-gradient vector of the objective function as the search direction. The q-gradient vector, or simply the q-gradient, is a generalization of the classical gradient vector based on the concept of Jackson's derivative from the q-calculus. Its use provides the algorithm an effective mechanism for escaping from local minima. The q-G method reduces to the Steepest Descent method when the parameter q tends to 1. The algorithm has three free parameters and it is implemented so that the search process gradually shifts from global exploration in the beginning to local exploitation in the end. We evaluated the q-G method on 34 test functions, and compared its performance with 34 optimization algorithms, including derivative-free algorithms and the Steepest Descent method. Our results show that the q-G method is competitive and has a great potential for solving multimodal optimization problems.

  7. q-trace for quantum groups and q-deformed Yang-Mills theory

    International Nuclear Information System (INIS)

    Isaev, A.P.; Popowicz, Z.

    1992-01-01

    The definitions of orbits and q-trace for the quantum groups are introduced. Then the q-trace is used to construct the invariants for the quantum group orbits and to formulate the q-deformed Yang-Mills theory. The amusing formal relation of the Weinberg type mixing angle with the quantum group deformation parameter is discussed. (orig.)

  8. The Inelastic Instrument suite at the SNS

    International Nuclear Information System (INIS)

    Granroth, Garrett E; Abernathy, Douglas L; Ehlers, Georg; Hagen, Mark E; Herwig, Kenneth W; Mamontov, Eugene; Ohl, Michael E; Wildgruber, Christoph U

    2008-01-01

    The instruments in the extensive suite of spectrometers at the SNS are in various stages of installation and commissioning. The Back Scattering Spectrometer (BASIS) is installed and is in commissioning. It's near backscattering analyzer crystals provide the 3 eV resolution as expected. BASIS will enter the user program in the fall of 2007. The ARCS wide angular-range thermal to epithermal neutron spectrometer will come on line in the fall of 2007 followed shortly by the Cold Neutron Chopper Spectrometer. These two direct geometry instruments provide moderate resolution and the ability to trade resolution for flux. In addition both instruments have detector coverage out to 140o to provide a large Q range. The SEQUOIA spectrometer, complete in 2008, is the direct geometry instrument that will provide fine resolution in the thermal to epithermal range. The Spin-Echo spectrometer, to be completed on a similar time scale, will provide the finest energy resolution worldwide. The HYSPEC spectrometer, available no later than 2011, will provide polarized capabilities and optimized flux in the thermal energy range. Finally, the Vision chemical spectrometer will use crystal analyzers to study energy transfers into the epithermal range

  9. Investigation into the limits of perturbation theory at low Q{sup 2} using HERA deep inelastic scattering data

    Energy Technology Data Exchange (ETDEWEB)

    Abt, I. [Max-Planck-Institut fuer Physik, Muenchen (Germany). Werner-Heisenberg-Institut; Cooper-Sarkar, A.M. [Oxford Univ. (United Kingdom). Dept. of Physics; Foster, B. [Oxford Univ. (United Kingdom). Dept. of Physics; Hamburg Univ. (Germany). I. Inst. of Experimental Physics; Deutsches Elektronen-Synchrotron (DESY), Hamburg (Germany); Myronenko, V.; Wichmann, K. [Deutsches Elektronen-Synchrotron (DESY), Hamburg (Germany); Wing, M. [University College London (United Kingdom). Dept. of Physics and Astronomy

    2017-07-18

    A phenomenological study of the final combined HERA data on inclusive deep inelastic scattering (DIS) has been performed. The data are presented and investigated for a kinematic range extending from values of the four-momentum transfer, Q{sup 2}, above 10{sup 4} GeV{sup 2} down to the lowest values observable at HERA of Q{sup 2}=0.045 GeV{sup 2} and Bjorken x, x{sub Bj}=6.10{sup -7}. The data are well described by fits based on perturbative quantum chromodynamics (QCD) using collinear factorisation and evolution of the parton densities encompassed in the DGLAP formalism from the highest Q{sup 2} down to Q{sup 2} of a few GeV{sup 2}. The Regge formalism with the soft Pomeron pole can describe the data up to Q{sup 2}∼0.65 GeV{sup 2}. The complete data set can be described by a new fit using the Abramowicz-Levin-Levy-Maor (ALLM) parameterisation. The region between the Regge and the perturbative QCD regimes is of particular interest.

  10. Best polynomial degree reduction on q-lattices with applications to q-orthogonal polynomials

    KAUST Repository

    Ait-Haddou, Rachid

    2015-06-07

    We show that a weighted least squares approximation of q-Bézier coefficients provides the best polynomial degree reduction in the q-L2-norm. We also provide a finite analogue of this result with respect to finite q-lattices and we present applications of these results to q-orthogonal polynomials. © 2015 Elsevier Inc. All rights reserved.

  11. Best polynomial degree reduction on q-lattices with applications to q-orthogonal polynomials

    KAUST Repository

    Ait-Haddou, Rachid; Goldman, Ron

    2015-01-01

    We show that a weighted least squares approximation of q-Bézier coefficients provides the best polynomial degree reduction in the q-L2-norm. We also provide a finite analogue of this result with respect to finite q-lattices and we present applications of these results to q-orthogonal polynomials. © 2015 Elsevier Inc. All rights reserved.

  12. Enhanced Maternal Origin of the 22q11.2 Deletion in Velocardiofacial and DiGeorge Syndromes

    DEFF Research Database (Denmark)

    Delio, Maria; Guo, Tingwei; McDonald-McGinn, Donna M

    2013-01-01

    Velocardiofacial and DiGeorge syndromes, also known as 22q11.2 deletion syndrome (22q11DS), are congenital-anomaly disorders caused by a de novo hemizygous 22q11.2 deletion mediated by meiotic nonallelic homologous recombination events between low-copy repeats, also known as segmental duplication...

  13. Field comparison of the Kistler 303 and the Q-Flex 1100 and 120 accelerometers

    International Nuclear Information System (INIS)

    Vortman, L.J.

    1981-04-01

    Three orthogonal components of acceleration were measured by three canisters, one containing Kistler 303 accelerometers, one Q-Flex 1100 accelerometers, and the other Q-Flex 1200 accelerometers. Measurements were made of ground motion from six different nuclear weapons tests with the three canisters located at the same station. The results from nine separate gages and associated measuring equipment were processed through the same data processing system, integrated to provide velocity and displacement, and combined into vector sums of the ground motion experienced by each canister. The differences in peak vector acceleration, velocity, and displacement were too small to justify a choice of one type of instrument over another on that basis alone

  14. q-analogue of summability of formal solutions of some linear q-difference-differential equations

    Directory of Open Access Journals (Sweden)

    Hidetoshi Tahara

    2015-01-01

    Full Text Available Let \\(q\\gt 1\\. The paper considers a linear \\(q\\-difference-differential equation: it is a \\(q\\-difference equation in the time variable \\(t\\, and a partial differential equation in the space variable \\(z\\. Under suitable conditions and by using \\(q\\-Borel and \\(q\\-Laplace transforms (introduced by J.-P. Ramis and C. Zhang, the authors show that if it has a formal power series solution \\(\\hat{X}(t,z\\ one can construct an actual holomorphic solution which admits \\(\\hat{X}(t,z\\ as a \\(q\\-Gevrey asymptotic expansion of order \\(1\\.

  15. The q-Onsager algebra and multivariable q-special functions

    Science.gov (United States)

    Baseilhac, Pascal; Vinet, Luc; Zhedanov, Alexei

    2017-09-01

    Two sets of mutually commuting q-difference operators x i and y j , i,j=1,...,N such that x i and y i generate a homomorphic image of the q-Onsager algebra for each i are introduced. The common polynomial eigenfunctions of each set are found to be entangled product of elementary Pochhammer functions in N variables and N+3 parameters. Under certain conditions on the parameters, they form two ‘dual’ bases of polynomials in N variables. The action of each operator with respect to its dual basis is block tridiagonal. The overlap coefficients between the two dual bases are expressed as entangled products of q-Racah polynomials and satisfy an orthogonality relation. The overlap coefficients between either one of these bases and the multivariable monomial basis are also considered. One obtains in this case entangled products of dual q-Krawtchouk polynomials. Finally, the ‘split’ basis in which the two families of operators act as block bidiagonal matrices is also provided.

  16. Could the BIC-Q be a decision-support tool to predict the development of asylum-seeking children?

    NARCIS (Netherlands)

    Zijlstra, A. Elianne; Kalverboer, Margrite E.; Post, Wendy J.; Ten Brummelaar, Mijntje D. C.; Knorth, Erik J.

    2013-01-01

    The Best Interest of the Child Questionnaire (BIC-Q) is an instrument to measure the quality of the childrearing environment. We used a sample of asylum-seeking children (N = 79) in the Netherlands to determine the relationship between the quality of the childrearing environment and the child's

  17. Low-kilovolt coherent electron diffractive imaging instrument based on a single-atom electron source

    Energy Technology Data Exchange (ETDEWEB)

    Lin, Chun-Yueh [Department of Physics, National Taiwan University, Taipei 10617, Taiwan (China); Chang, Wei-Tse; Chen, Yi-Sheng; Hwu, En-Te; Chang, Chia-Seng; Hwang, Ing-Shouh, E-mail: ishwang@phys.sinica.edu.tw [Institute of Physics, Academia Sinica, Nankang, Taipei 11529, Taiwan (China); Hsu, Wei-Hao [Department of Materials Science and Engineering, National Tsing Hua University, Hsinchu 30013, Taiwan (China)

    2016-03-15

    In this work, a transmission-type, low-kilovolt coherent electron diffractive imaging instrument was constructed. It comprised a single-atom field emitter, a triple-element electrostatic lens, a sample holder, and a retractable delay line detector to record the diffraction patterns at different positions behind the sample. It was designed to image materials thinner than 3 nm. The authors analyzed the asymmetric triple-element electrostatic lens for focusing the electron beams and achieved a focused beam spot of 87 nm on the sample plane at the electron energy of 2 kV. High-angle coherent diffraction patterns of a suspended graphene sample corresponding to (0.62 Å){sup −1} were recorded. This work demonstrated the potential of coherent diffractive imaging of thin two-dimensional materials, biological molecules, and nano-objects at a voltage between 1 and 10 kV. The ultimate goal of this instrument is to achieve atomic resolution of these materials with high contrast and little radiation damage.

  18. Development of a low-cost NIR instrument for minced meat analysis: Part 1 - Spectrophotometer and sample presentations

    Science.gov (United States)

    The feasibility of using a compact, low-cost NIR spectrophotometer to predict moisture (MC) and total fat content of minced pork was demonstrated. Results were compared with those obtained using two research type instruments with high signal to noise ratio (S/N). The NIR measuring head of the compac...

  19. Measuring self-reported health in low-income countries: piloting three instruments in semi-rural Burkina Faso

    Directory of Open Access Journals (Sweden)

    Yulia Blomstedt

    2012-07-01

    Full Text Available Background: National surveys in low-income countries increasingly rely on self-reported measures of health. The ease, speed, and economy of collecting self-reports of health make such collection attractive for rapid appraisals. However, the interpretation of these measures is complicated since different cultures understand and respond to the same question in different ways. Objective: The aim of this pilot study was to develop a culturally sensitive tool to study the self-reported health (SRH of the local adult population in Burkina Faso. Design: The study was carried out in the 2009 rainy season. The sample included 27 men and 25 women aged 18 or older who live in semi-urban Nouna, Burkina Faso. Three culturally adapted instruments were tested: a SRH question, a wooden visual analogue scale (VAS, and a drawn VAS. Respondents were asked to explain their answers to each instrument. The narratives were analyzed with the content analysis technique, and the prevalence of poor SRH was estimated from the quantitative data by stratification for respondent background variables (sex, age, literacy, education, marital status, ethnicity, chronic diseases. The correlation between the instruments was tested with Spearman's correlation test. Results: The SRH question showed a 38.5% prevalence of poor SRH and 44.2% prevalence with both VAS. The correlation between the VAS was 0.89, whereas the correlation between the VAS and the SRH question was 0.60–0.64. Nevertheless, the question used as the basis of each instrument was culturally sensitive and clear to all respondents. Analysis of the narratives shows that respondents clearly differentiated between the various health statuses. Conclusion: In this pilot, we developed and tested a new version of the SRH question that may be more culturally sensitive than its non-adapted equivalents. Additional insight into this population's understanding and reporting of health was also obtained. A larger sample is needed

  20. q-Space imaging using small magnetic field gradient

    International Nuclear Information System (INIS)

    Umezawa, Eizou; Yamaguchi, Kojiro; Yoshikawa, Mayo; Ueoku, Sachiko; Tanaka, Eiji

    2006-01-01

    q-space diffusion analysis is a method to obtain the probability density function of the translational displacement of diffusing water molecules. Several quantities can be extracted from the function that indicate a characteristic of the water diffusion in tissue, e.g., the mean displacement of the diffusion, probability for zero displacement, and kurtosis of the function. These quantities are expected to give information about the microstructure of tissues in addition to that obtained from the apparent diffusion coefficient (ADC); however, this method requires high q (i.e., high b) values, which are undesirable in practical applications of the method using clinical magnetic resonance (MR) imaging equipment. We propose a method to obtain certain quantities that indicate a characteristic of the diffusion and that uses low q-value measurements. The quantities we can obtain are the moments of translational displacement, R; the n-th order moment is defined as the average of R n (n: integer). Kurtosis can also be calculated from the second and fourth moments. We tried to map the moments and kurtosis using clinical MR imaging equipment. We also estimated the inherent errors of the moments obtained. Our method requires precision in measuring spin echo signals and setting q values rather than using high q-value measurements. Although our results show that further error reductions are desired, our method is workable using ordinary clinical MR imaging equipment. (author)

  1. Construction of LDPC codes over GF(q) with modified progressive edge growth

    Institute of Scientific and Technical Information of China (English)

    CHEN Xin; MEN Ai-dong; YANG Bo; QUAN Zi-yi

    2009-01-01

    A parity check matrix construction method for constructing a low-density parity-check (LDPC) codes over GF(q) (q>2) based on the modified progressive edge growth (PEG) algorithm is introduced. First, the nonzero locations of the parity check matrix are selected using the PEG algorithm. Then the nonzero elements are defined by avoiding the definition of subcode. A proof is given to show the good minimum distance property of constructed GF(q)-LDPC codes. Simulations are also presented to illustrate the good error performance of the designed codes.

  2. On the link between the q-profile and internal transport barriers

    Energy Technology Data Exchange (ETDEWEB)

    Baranov, Yu F [EURATOM/UKAEA Fusion Association, Culham Science Centre, Abingdon, Oxon, OX14 3DB (United Kingdom); Garbet, X [Association Euratom-CEA, CE de Cadarache, F-13108, St Paul lez Durance (France); Hawkes, N C [EURATOM/UKAEA Fusion Association, Culham Science Centre, Abingdon, Oxon, OX14 3DB (United Kingdom); Alper, B [EURATOM/UKAEA Fusion Association, Culham Science Centre, Abingdon, Oxon, OX14 3DB (United Kingdom); Barnsley, R [EURATOM/UKAEA Fusion Association, Culham Science Centre, Abingdon, Oxon, OX14 3DB (United Kingdom); Challis, C D [EURATOM/UKAEA Fusion Association, Culham Science Centre, Abingdon, Oxon, OX14 3DB (United Kingdom); Giroud, C [EURATOM/UKAEA Fusion Association, Culham Science Centre, Abingdon, Oxon, OX14 3DB (United Kingdom); Joffrin, E [Association Euratom-CEA, CE de Cadarache, F-13108, St Paul lez Durance (France); Mantsinen, M [Helsinki University of Technology, Association Euratom-Tekes (Finland); Orsitto, F [Associazione EURATOM-ENEA sulla Fusione, C.R. Frascati, Frascati (Italy); Parail, V [EURATOM/UKAEA Fusion Association, Culham Science Centre, Abingdon, Oxon, OX14 3DB (United Kingdom); Sharapov, S E [EURATOM/UKAEA Fusion Association, Culham Science Centre, Abingdon, Oxon, OX14 3DB (United Kingdom)

    2004-08-01

    Numerous experiments were performed on JET to clarify the link between rational q, magnetic shear and internal transport barriers (ITBs) by varying the q-profile from a monotonic one to one with a central reversed shear (Challis et al 2002 Plasma Phys. Control. Fusion 44 1031). The q-profile was found to be crucial in two cases: for ITB formation in the presence of a strong negative magnetic shear and for ITBs in the vicinity of low order rational q surfaces with a small magnetic shear. The ITBs of these two types have been modelled and analysed in this work using transport codes (TRANSP, JETTO, TRB). Transport coefficients were calculated using several widely used theories of micro-turbulence and compared with data deduced from the experiment to verify the applicability of the theories. Different underlying physical mechanisms were found to be responsible for ITB formation in a negative magnetic shear and in the vicinity of a rational minimum q.

  3. Technical presentation - KEITHLEY Instruments - CANCELLED

    CERN Multimedia

    FI Department

    2009-01-01

    10 March 2009 13:30 – 15:30, Council Chamber, Bldg. 503 Keithley markets highly accurate instruments and data acquisition products, as well as complete system solutions for high-volume production and assembly testing. Keithley Instruments, Inc. designs, develops, manufactures and markets complex electronic instruments and systems geared to the specialized needs of electronics manufacturers for high-performance production testing, process monitoring, product development and research. Products and Services: Digital Multimeters and Data Acquisition Systems Current / Voltage Source and Measure Products Low Current / High Resistance Measurement Products Function/Pulse/Arbitrary/Pattern Generators Low Voltage/Low Resistance Measurement Products RF Spectrum Analyzer / RF Signal Generator / RF Switching Semiconductor Device Characterization Program: Topic 1: Welcome and short overview of new Products SMU 26XXA / ARB Generator 3390 / DMM 3706 / E-Meter 6517B Topic 2a: Te...

  4. Coenzyme Q10 Status as a Determinant of Muscular Strength in Two Independent Cohorts.

    Directory of Open Access Journals (Sweden)

    Alexandra Fischer

    Full Text Available Aging is associated with sarcopenia, which is a loss of skeletal muscle mass and function. Coenzyme Q10 (CoQ10 is involved in several important functions that are related to bioenergetics and protection against oxidative damage; however, the role of CoQ10 as a determinant of muscular strength is not well documented. The aim of the present study was to evaluate the determinants of muscular strength by examining hand grip force in relation to CoQ10 status, gender, age and body mass index (BMI in two independent cohorts (n = 334, n = 967. Furthermore, peak flow as a function of respiratory muscle force was assessed. Spearman's correlation revealed a significant positive association between CoQ10/cholesterol level and hand grip in the basic study population (p<0.01 as well as in the validation population (p<0.001. In the latter, we also found a negative correlation with the CoQ10 redox state (p<0.01, which represents a lower percentage of the reduced form of CoQ10 (ubiquinol in subjects who exhibit a lower muscular strength. Furthermore, the age of the subjects showed a negative correlation with hand grip (p<0.001, whereas BMI was positively correlated with hand grip (p<0.01, although only in the normal weight subgroup (BMI <25 kg/m2. Analysis of the covariance (ANCOVA with hand grip as the dependent variable revealed CoQ10/cholesterol as a determinant of muscular strength and gender as the strongest effector of hand grip. In conclusion, our data suggest that both a low CoQ10/cholesterol level and a low percentage of the reduced form of CoQ10 could be an indicator of an increased risk of sarcopenia in humans due to their negative associations to upper body muscle strength, peak flow and muscle mass.

  5. Maths-type q-deformed coherent states for q>1

    International Nuclear Information System (INIS)

    Quesne, C.; Penson, K.A.; Tkachuk, V.M.

    2003-01-01

    Maths-type q-deformed coherent states with q>1 allow a resolution of unity in the form of an ordinary integral. They are sub-Poissonian and squeezed. They may be associated with a harmonic oscillator with minimal uncertainties in both position and momentum and are intelligent coherent states for the corresponding deformed Heisenberg algebra

  6. Two girls with a de novo Xq rearrangement of paternal origin: t(X;9(q24;q12 or rea(Xdup q

    Directory of Open Access Journals (Sweden)

    Ana I. Vásquez-Velásquez

    2016-04-01

    Full Text Available Objective: We report on two rare Xq rearrangements, namely a t(X;9(q24;q12 found in a mildly-affected girl (Patient 1 and a rea(Xdup q concomitant with a rob(14;21mat in a Down syndrome girl (Patient 2. Case report: Both rearrangements were characterized by banding techniques [Giemsa (G, constitutive heterochromatin (C, and bromodeoxyuridine (BrdU pulse], fluorescence in situ hybridization (FISH assays, human androgen receptor (HUMAR assays, and microarray analyses. Patient 1 had a t(X;9(q24;q12dn. Patient 2 had a de novo rea(X(qter→q23 or q24::p11.2→qter concomitant with an unbalanced rob(14;21mat. X-Inactivation studies in metaphases and DNA revealed a fully skewed inactivation: the normal homolog was silenced in Patient 1 and the rea(X in Patient 2. Both rearranged X chromosomes were of paternal descent. Microarray analyses revealed no imbalances in Patient 1 whereas loss of Xp (∼52 Mb and duplication of Xq (∼44 Mb and 21q were confirmed in Patient 2. Conclusion: Our observations further document the cytogenetic heterogeneity and predominant paternal origin of certain de novo X-chromosome rearrangements.

  7. Nucleonic instruments from VUPJT Tesla

    International Nuclear Information System (INIS)

    Smola, J.

    1986-01-01

    The instruments currently produced by Tesla Premysleni are listed and briefly characterized. They include a low level alpha-beta counter, an automatic low level alpha-beta counter, detection units for environmental sample counting, instruments for measuring specific activity of liquids and radon concentration in water, a radioactive aerosol meter, dose ratemeters, portable alpha-beta indicators for surface contamintion monitoring, neutron monitors, single-, two- and three-channel spectrometric units. (M.D.)

  8. Q4 2017/Q1 2018 Solar Industry Update

    Energy Technology Data Exchange (ETDEWEB)

    Feldman, David J [National Renewable Energy Laboratory (NREL), Golden, CO (United States); Margolis, Robert M [National Renewable Energy Laboratory (NREL), Golden, CO (United States); Hoskins, Jack [U.S. Department of Energy

    2018-05-16

    This technical presentation provides an update on the major trends that occurred in the solar industry in Q4 2017 and Q1 2018. Major topics of focus include global and U.S. supply and demand, module and system price, investment trends and business models, and updates on U.S. government programs supporting the solar industry.

  9. Fatigue following Acute Q-Fever: A Systematic Literature Review

    Science.gov (United States)

    Delsing, Corine E.; Bleijenberg, Gijs; Langendam, Miranda; Timen, Aura; Bleeker-Rovers, Chantal P.

    2016-01-01

    Background Long-term fatigue with detrimental effects on daily functioning often occurs following acute Q-fever. Following the 2007–2010 Q-fever outbreak in the Netherlands with over 4000 notified cases, the emphasis on long-term consequences of Q-fever increased. The aim of this study was to provide an overview of all relevant available literature, and to identify knowledge gaps regarding the definition, diagnosis, background, description, aetiology, prevention, therapy, and prognosis, of fatigue following acute Q-fever. Design A systematic review was conducted through searching Pubmed, Embase, and PsycInfo for relevant literature up to 26th May 2015. References of included articles were hand searched for additional documents, and included articles were quality assessed. Results Fifty-seven articles were included and four documents classified as grey literature. The quality of most studies was low. The studies suggest that although most patients recover from fatigue within 6–12 months after acute Q-fever, approximately 20% remain chronically fatigued. Several names are used indicating fatigue following acute Q-fever, of which Q-fever fatigue syndrome (QFS) is most customary. Although QFS is described to occur frequently in many countries, a uniform definition is lacking. The studies report major health and work-related consequences, and is frequently accompanied by nonspecific complaints. There is no consensus with regard to aetiology, prevention, treatment, and prognosis. Conclusions Long-term fatigue following acute Q-fever, generally referred to as QFS, has major health-related consequences. However, information on aetiology, prevention, treatment, and prognosis of QFS is underrepresented in the international literature. In order to facilitate comparison of findings, and as platform for future studies, a uniform definition and diagnostic work-up and uniform measurement tools for QFS are proposed. PMID:27223465

  10. Psychometric Properties of the Korean Version of the Overactive Bladder Questionnaire (OAB-q in a Korean Population

    Directory of Open Access Journals (Sweden)

    Seung-June Oh

    2012-06-01

    Full Text Available Purpose Psychometric properties of the overactive bladder questionnaire (OAB-q were recently examined. However, since the cross-cultural adaptation of a non-English version of the OAB-q has never been demonstrated, we evaluated the psychometric properties of a Korean version of the OAB-q in a Korean population with OAB. Methods A prospective cohort study involving 116 women with 58 OAB and 58 control subjects was performed and convergent validity was assessed. Total and subscale OAB-q scores of the control and OAB groups were compared to their sensitivity to score changes before and after administering anti-cholinergic medication for 12 weeks. Short form 36 and King's health questionnaire (KHQ were also used for comparison or correlation. Results Assessment of face validity showed that the Korean version of the OAB-q was reasonable with OAB-q subscale scores being significantly different between the control and patient groups. Significant correlation (range, -0.29 to -0.81 was found between the OAB-q scores and KHQ results for the OAB patients. Cronbach's alpha coefficients (range, 0.77 to 0.95 indicated excellent internal consistency and test-retest analysis involving 35 OAB patients showed that each questions as well as subscale scores were reproducible. Each score of OAB-q also showed statistically significant sensitivity to changes following anti-muscarinic treatment for OAB (n=27, P<0.001 except for social, P=0.059. Conclusions The Korean version of the OAB-q is a valid and reliable instrument to measure outcomes in Korean patients with OAB.

  11. Q fever in Greenland

    DEFF Research Database (Denmark)

    Koch, Anders; Svendsen, Claus Bo; Christensen, Jens Jorgen

    2010-01-01

    We report a patient with Q fever endocarditis in a settlement in eastern Greenland (Isortoq, Ammassalik area). Likely animal sources include sled dogs and seals. Q fever may be underdiagnosed in Arctic areas but may also represent an emerging infection.......We report a patient with Q fever endocarditis in a settlement in eastern Greenland (Isortoq, Ammassalik area). Likely animal sources include sled dogs and seals. Q fever may be underdiagnosed in Arctic areas but may also represent an emerging infection....

  12. Validity of the Greek Eating Disorder Examination Questionnaire 6.0 (EDE-Q-6.0) among Greek adolescents.

    Science.gov (United States)

    Pliatskidou, S; Samakouri, M; Kalamara, E; Papageorgiou, E; Koutrouvi, K; Goulemtzakis, C; Nikolaou, E; Livaditis, M

    2015-01-01

    scale the instrument screens with a sensitivity (Se) of 89.5% and a specificity (Sp) of 73.1%, a Positive Predictive Value (PPV) of 34.7% and a Negative Predictive Value (NPV) of 97.8% The same analyses for both sexes revealed a cut-off point of 2.612 for females and of 3.125 for males on the global EDE-Q-6.0 score (Se=84.62%, Sp=73.33% for females and Se=83.33%, Sp= 84.09% for males), yielding a PPV and a NPV of 35.5% and of 96.5% for females and 41.7% and 97.4% for males, respectively. A very low agreement level, between EDE-Q and interview, was observed regarding the presence of objective bulimic episodes (OBEs) [k=0.191 (SE=0.057)] and the unhealthy weight control behaviors [k=0.295 (SE=0.073)]. Positive correlations were found between EAT-26 and EDE-Q-6.0 for both global scale and subscales (rho=0.50-0.57). The results suggest that EDE-Q-6.0, when using its global score, appears to be a proper screening tool for assessing the core psychopathology of eating disorders in community samples in two-stage screening studies since it distinguishes very well the cases from the non-cases. However, the assessment of the presence and frequency of pathological behaviours which characterize EDs appears to be problematic since adolescents, especially the younger ones, misunderstood terms like large amount of food and loss of control or misinterpret the motivation for excessive exercise. Therefore, marked discrepancies were observed between pathological behaviors self-reported at questionnaire and those detected at interview. We may assume that giving participants more information regarding the definition of these concepts may increase the accuracy with which the participants report these behaviors.

  13. Formation of q bar q resonances in the bar NN system

    International Nuclear Information System (INIS)

    Ivanov, N.Ya.

    1995-01-01

    The formation of q bar q resonances lying on the leading Regge trajectories in the bar NN system is studied in the quark-gluon string model. The model predicts strong suppression of the decays of q bar q states into bar NN pairs in relation to two-meson modes. The author's analysis shows that the contributions of the resonances f 4 (2050) (I G J PC = 0 + 4 ++ ), ρ 5 (2240) (I G J PC = 1 + 5 -- ), and f 6 (2510) (I G J PC = 0 + 6 ++ ) to the processes of two-meson bar NN annihilation (bar pp → ππ, bar KK, hor-ellipsis) are about 1% of the corresponding experimental integrated cross sections. 30 refs., 2 figs., 1 tab

  14. Numerical and Experimental Study of the Q Factor of High-Q Micropillar Cavities

    DEFF Research Database (Denmark)

    Gregersen, Niels; Reitzenstein, S.; Kistner, C.

    2010-01-01

    Micropillar cavities are potential candidates for high-efficiency single-photon sources and are testbeds for cavity quantum electrodynamics experiments. In both applications a high quality (Q) factor is desired. It was recently shown that the Q of high-Q semiconductor micropillar cavities exhibit...

  15. Q fever outbreak in the terraced vineyards of Lavaux, Switzerland

    Directory of Open Access Journals (Sweden)

    C. Bellini

    2014-07-01

    Full Text Available Coxiella burnetii infection (Q fever is a widespread zoonosis with low endemicity in Switzerland, therefore no mandatory public report was required. A cluster of initially ten human cases of acute Q fever infections characterized by prolonged fever, asthenia and mild hepatitis occurred in 2012 in the terraced vineyard of Lavaux. Epidemiological investigations based on patients’ interviews and veterinary investigations included environmental sampling as well as Coxiella-specific serological assay and molecular examinations (real-time PCR in vaginal secretions of suspected sheep. These investigations demonstrated that 43% of sheep carried the bacteria whereas 30% exhibited anti-Coxiella antibodies. Mitigation measures, including limiting human contacts with the flock, hygiene measures, flock vaccination and a public official alert, have permitted the detection of four additional human cases and the avoidance of a much larger outbreak. Since November 2012, mandatory reporting of Q fever to Swiss public health authorities has been reintroduced. A close follow up of human cases will be necessary to identify chronic Q fever.

  16. Mass spectra for q c q ¯ c ¯, s c s ¯ c ¯, q b q ¯ ¯, s b s ¯ ¯ tetraquark states with JP C=0++ and 2++

    Science.gov (United States)

    Chen, Wei; Chen, Hua-Xing; Liu, Xiang; Steele, T. G.; Zhu, Shi-Lin

    2017-12-01

    We have studied the mass spectra of the hidden-charm/bottom q c q ¯c ¯, s c s ¯c ¯ and q b q ¯b ¯, s b s ¯b ¯ tetraquark states with JP C=0++ and 2++ in the framework of QCD sum rules. We construct ten scalar and four tensor interpolating currents in a systematic way and calculate the mass spectra for these tetraquark states. The X*(3860 ) may be either an isoscalar tetraquark state or χc 0(2 P ). If the X*(3860 ) is a tetraquark candidate, our results prefer the 0++ option over the 2++ one. The X (4160 ) may be classified as either the scalar or tensor q c q ¯c ¯ tetraquark state, while the X (3915 ) favors a 0++ q c q ¯c ¯ or s c s ¯c ¯ tetraquark assignment over the tensor one. The X (4350 ) cannot be interpreted as a s c s ¯c ¯ tetraquark with either JP C=0++ or 2++.

  17. BPS dynamics of the triple (p,q) string junction

    International Nuclear Information System (INIS)

    Rey, S.-J.; Yee, J.-T.

    1998-01-01

    We study the dynamics of the triple junction of (p,q) strings in type IIB string theory. We probe the tension and mass density of (p,q) strings by studying harmonic fluctuations of the triple junction. We show that they agree perfectly with the BPS formula provided a suitable geometric interpretation of the junction is given. We provide a precise statement of the BPS limit and force-balance property. At weak coupling and sufficiently dense limit, we argue that a (p,q) string embedded in the string network is a 'wiggly string', whose low-energy dynamics can be described via a renormalization group evolved, smooth effective non-relativistic string. We also suggest the possibility that, upon type IIB strings being promoted to the M-theory membrane, there can exist 'evanescent' bound-states at the triple junction in the continuum. (orig.)

  18. Runaway electrons and rational q-surfaces in a tokamak

    International Nuclear Information System (INIS)

    Cheetham, A.D.; Hogg, G.R.; Kuwahara, H.; Morton, A.H.

    1983-01-01

    Results of measurements with LT-4 of runaway electron behaviour during the current rise stage of discharges when q = rBsub(T)/RBsub(p) (where r and R are minor and major radii, Bsub(T) and Bsub(p) are toroidal and poloidal magnetic fields) is changing continuously are reported. The results establish a role for outward moving rational q regions in removing runaway electrons from a tokamak plasma. The model indicates that as well as carrying a proportion of low energy runaways with them the rational q regions also scatter high energy electrons from the discharge. This leads to an upper limit for the energy of fully confined electrons. The size of the runaway population might be minimised by controlling the rate of movement of rational surfaces. This would be achieved by programming the rate of rise of the plasma current

  19. q-Deformed Kink solutions

    International Nuclear Information System (INIS)

    Lima, A.F. de

    2003-01-01

    The q-deformed kink of the λφ 4 -model is obtained via the normalisable ground state eigenfunction of a fluctuation operator associated with the q-deformed hyperbolic functions. The kink mass, the bosonic zero-mode and the q-deformed potential in 1+1 dimensions are found. (author)

  20. Free radical scavenging activity of coenzyme Q measured by a chemiluminescent assay

    International Nuclear Information System (INIS)

    Battino, Maurizio; Ferri, Elida; Girotti, Stefano; Lenaz, Giorgio

    1991-01-01

    Involvement of coenzyme Q (CoQ) in anti-oxydant activities, in addition to its major redox role, has frequently been suggested in recent years. In order to elucidate if CoQ could really be engaged in scavenging free radicals produced endogenously in a biological system, an experimental system was developed in which beef heart mitochondria in the presence of a saturating NADH concentration and of rotenone produce free radicals. The presence of oxygen-reactive forms was easily detected by a luminol-dependent chemiluminescence process. The chemi-luminescence assay showed that short-chain CoQ homologues can act as pro-oxidants, enhancing free radical effects, while exogenous coenzyme Q 10 could scavenge free radicals, especially at very low concentration. In this system, exogenous CoQ 10 was more effective than α-tocopherol at the same concentration in scavenging free radicals. The molecular mechanism that leads to this activity is still unclear, but these results are of biochemical importance because they indicate that CoQ may act as an anti=oxidant in situations mimicking physiopathological conditions. This direct chemiluminescent method is promising for studies of biochemical processes which involve active oxygen species. (author). 24 refs.; 4 figs

  1. Note: Detector collimators for the nanoscale ordered materials diffractometer instrument at the Spallation Neutron Source

    Energy Technology Data Exchange (ETDEWEB)

    Tamalonis, A. [Materials Development, Inc., Arlington Heights, Illinois 60004 (United States); Weber, J. K. R., E-mail: rweber@anl.gov; Alderman, O. L. G. [Materials Development, Inc., Arlington Heights, Illinois 60004 (United States); Argonne National Laboratory, Argonne, Illinois 60439 (United States); Neuefeind, J. C.; Carruth, J. [Oak Ridge National Laboratory, Oak Ridge, Tennessee 37830 (United States); Skinner, L. B. [Materials Development, Inc., Arlington Heights, Illinois 60004 (United States); Argonne National Laboratory, Argonne, Illinois 60439 (United States); Stony Brook University, Stony Brook, New York 11794 (United States); Benmore, C. J. [Argonne National Laboratory, Argonne, Illinois 60439 (United States)

    2015-09-15

    Five neutron collimator designs were constructed and tested at the nanoscale ordered materials diffractometer (NOMAD) instrument. Collimators were made from High Density PolyEthylene (HDPE) or 5% borated HDPE. In all cases, collimators improved the signal to background ratio and reduced detection of secondary scattering. In the Q-range 10-20 Å{sup −1}, signal to background ratio improved by factors of approximately 1.6 and 2.0 for 50 and 100 mm deep collimators, respectively. In the Q-range 40-50 Å{sup −1}, the improvement factors were 1.8 and 2.7. Secondary scattering as measured at Q ∼ 9.5 Å{sup −1} was significantly decreased when the collimators were installed.

  2. q-fractional calculus and equations

    CERN Document Server

    Annaby, Mahmoud H

    2012-01-01

    This nine-chapter monograph introduces a rigorous investigation of q-difference operators in standard and fractional settings. It starts with elementary calculus of q-differences and integration of Jackson’s type before turning to q-difference equations. The existence and uniqueness theorems are derived using successive approximations, leading to systems of equations with retarded arguments. Regular  q-Sturm–Liouville theory is also introduced; Green’s function is constructed and the eigenfunction expansion theorem is given. The monograph also discusses some integral equations of Volterra and Abel type, as introductory material for the study of fractional q-calculi. Hence fractional q-calculi of the types Riemann–Liouville; Grünwald–Letnikov;  Caputo;  Erdélyi–Kober and Weyl are defined analytically. Fractional q-Leibniz rules with applications  in q-series are  also obtained with rigorous proofs of the formal  results of  Al-Salam-Verma, which remained unproved for decades. In working ...

  3. A characterization of the desarguesian planes of order q2 by SL(2,q

    Directory of Open Access Journals (Sweden)

    D. A. Foulser

    1983-01-01

    Full Text Available The main result is that if the translation complement of a translation plane of order q2 contains a group isomorphic to SL(2,q and if the subgroups of order q are elations (shears, then the plane is Desarguesian. This generalizes earlier work of Walker, who assumed that the kernel of the plane contained GF(q.

  4. Psychometric properties of the Belgian coach version of the coach-athlete relationship questionnaire (CART-Q).

    Science.gov (United States)

    Balduck, A-L; Jowett, S

    2010-10-01

    The study examined the psychometric properties of the Belgian coach version of the Coach-Athlete Relationship Questionnaire (CART-Q). The questionnaire includes three dimensions (Closeness, Commitment, and Complementarity) in a model that intends to measure the quality of the coach-athlete relationship. Belgian coaches (n=144) of athletes who performed at various competition levels in such sports as football, basketball, and volleyball responded to the CART-Q and to the Leadership Scale for Sport (LSS). A confirmatory factor analysis proved to be slightly more satisfactory for a three-order factor model, compared with a hierarchical first-order factor model. The three factors showed acceptable internal consistency scores. Moreover, functional associations between the three factors and coach leadership behaviors were found offering support to the instrument's concurrent validity. The findings support previous validation studies and verify the psychometric properties of the CART-Q applied to Belgian coaches of team sports. © 2009 John Wiley & Sons A/S.

  5. Nested Inversion Polymorphisms Predispose Chromosome 22q11.2 to Meiotic Rearrangements.

    Science.gov (United States)

    Demaerel, Wolfram; Hestand, Matthew S; Vergaelen, Elfi; Swillen, Ann; López-Sánchez, Marcos; Pérez-Jurado, Luis A; McDonald-McGinn, Donna M; Zackai, Elaine; Emanuel, Beverly S; Morrow, Bernice E; Breckpot, Jeroen; Devriendt, Koenraad; Vermeesch, Joris R

    2017-10-05

    Inversion polymorphisms between low-copy repeats (LCRs) might predispose chromosomes to meiotic non-allelic homologous recombination (NAHR) events and thus lead to genomic disorders. However, for the 22q11.2 deletion syndrome (22q11.2DS), the most common genomic disorder, no such inversions have been uncovered as of yet. Using fiber-FISH, we demonstrate that parents transmitting the de novo 3 Mb LCR22A-D 22q11.2 deletion, the reciprocal duplication, and the smaller 1.5 Mb LCR22A-B 22q11.2 deletion carry inversions of LCR22B-D or LCR22C-D. Hence, the inversions predispose chromosome 22q11.2 to meiotic rearrangements and increase the individual risk for transmitting rearrangements. Interestingly, the inversions are nested or flanking rather than coinciding with the deletion or duplication sizes. This finding raises the possibility that inversions are a prerequisite not only for 22q11.2 rearrangements but also for all NAHR-mediated genomic disorders. Copyright © 2017. Published by Elsevier Inc.

  6. Assessment of economic instruments for countries with low municipal waste management performance: An approach based on the analytic hierarchy process.

    Science.gov (United States)

    Kling, Maximilian; Seyring, Nicole; Tzanova, Polia

    2016-09-01

    Economic instruments provide significant potential for countries with low municipal waste management performance in decreasing landfill rates and increasing recycling rates for municipal waste. In this research, strengths and weaknesses of landfill tax, pay-as-you-throw charging systems, deposit-refund systems and extended producer responsibility schemes are compared, focusing on conditions in countries with low waste management performance. In order to prioritise instruments for implementation in these countries, the analytic hierarchy process is applied using results of a literature review as input for the comparison. The assessment reveals that pay-as-you-throw is the most preferable instrument when utility-related criteria are regarded (wb = 0.35; analytic hierarchy process distributive mode; absolute comparison) mainly owing to its waste prevention effect, closely followed by landfill tax (wb = 0.32). Deposit-refund systems (wb = 0.17) and extended producer responsibility (wb = 0.16) rank third and fourth, with marginal differences owing to their similar nature. When cost-related criteria are additionally included in the comparison, landfill tax seems to provide the highest utility-cost ratio. Data from literature concerning cost (contrary to utility-related criteria) is currently not sufficiently available for a robust ranking according to the utility-cost ratio. In general, the analytic hierarchy process is seen as a suitable method for assessing economic instruments in waste management. Independent from the chosen analytic hierarchy process mode, results provide valuable indications for policy-makers on the application of economic instruments, as well as on their specific strengths and weaknesses. Nevertheless, the instruments need to be put in the country-specific context along with the results of this analytic hierarchy process application before practical decisions are made. © The Author(s) 2016.

  7. Deletion of 7q33-q35 in a Patient with Intellectual Disability and Dysmorphic Features: Further Characterization of 7q Interstitial Deletion Syndrome

    Directory of Open Access Journals (Sweden)

    Kristen Dilzell

    2015-01-01

    Full Text Available This case report concerns a 16-year-old girl with a 9.92 Mb, heterozygous interstitial chromosome deletion at 7q33-q35, identified using array comparative genomic hybridization. The patient has dysmorphic facial features, intellectual disability, recurrent infections, self-injurious behavior, obesity, and recent onset of hemihypertrophy. This patient has overlapping features with previously reported individuals who have similar deletions spanning the 7q32-q36 region. It has been difficult to describe an interstitial 7q deletion syndrome due to variations in the sizes and regions in the few patients reported in the literature. This case contributes to the further characterization of an interstitial distal 7q deletion syndrome.

  8. Low current approach to ignition

    International Nuclear Information System (INIS)

    Cenacchi, G.; Sugiyama, L.; Airoldi, A.; Coppi, B.

    1996-01-01

    The open-quotes standardclose quotes path to achieve ignition conditions so far has been that of producing plasmas with the maximum current and poloidal field that axe compatible with the applied toroidal field and the geometry of the adopted configuration (the low q a approach.) The other approach is that motivated by recent experiments with reversed shear configurations, with relatively low currents and high fields corresponding to high values of q a (e-g., q a ≅ 6). While the first approach can be pursued with ohmic heating alone, the second one necessarily involves an auxiliary heating system. One of the advantages of this approach is that the onset of large scale internal modes can be avoided as q(ψ) is kept above 1 over the entire plasma column. Since quite peaked density profiles are produced in the regimes where enhanced confinement is observed, the α-particle power levels for which ignition can be reached and therefore the thermal wall loading on the first wall, can be reduced relatively to the standard, low q a , approach. The possibility is considered that ignition is reached in the reversed shear, high q a , regime and that this is followed by a transition to non-reversed profiles, or even the low q a regime, assuming that the excitation of modes involving magnetic reconnection will not undermine the needed degree of confinement. These results have been demonstrated by numerical transport simulation for the Ignitor-Ult machine, but are applicable to all high field ignition experiments

  9. The Escherichia coli COG1738 Member YhhQ Is Involved in 7-Cyanodeazaguanine (preQ0 Transport

    Directory of Open Access Journals (Sweden)

    Rémi Zallot

    2017-02-01

    Full Text Available Queuosine (Q is a complex modification of the wobble base in tRNAs with GUN anticodons. The full Q biosynthesis pathway has been elucidated in Escherichia coli. FolE, QueD, QueE and QueC are involved in the conversion of guanosine triphosphate (GTP to 7-cyano-7-deazaguanine (preQ0, an intermediate of increasing interest for its central role in tRNA and DNA modification and secondary metabolism. QueF then reduces preQ0 to 7-aminomethyl-7-deazaguanine (preQ1. PreQ1 is inserted into tRNAs by tRNA guanine(34 transglycosylase (TGT. The inserted base preQ1 is finally matured to Q by two additional steps involving QueA and QueG or QueH. Most Eubacteria harbor the full set of Q synthesis genes and are predicted to synthesize Q de novo. However, some bacteria only encode enzymes involved in the second half of the pathway downstream of preQ0 synthesis, including the signature enzyme TGT. Different patterns of distribution of the queF, tgt, queA and queG or queH genes are observed, suggesting preQ0, preQ1 or even the queuine base being salvaged in specific organisms. Such salvage pathways require the existence of specific 7-deazapurine transporters that have yet to be identified. The COG1738 family was identified as a candidate for a missing preQ0/preQ1 transporter in prokaryotes, by comparative genomics analyses. The existence of Q precursor salvage was confirmed for the first time in bacteria, in vivo, through an indirect assay. The involvement of the COG1738 in salvage of a Q precursor was experimentally validated in Escherichia coli, where it was shown that the COG1738 family member YhhQ is essential for preQ0 transport.

  10. The Bus Extension Module Design and Verification of POSAFE-Q Using LVDS

    International Nuclear Information System (INIS)

    Lee, Youn Sang; Song, Seung Whan; No, Young Hun; Yoo, Kwan Woo

    2012-01-01

    This paper described the Bus Extension Module using Low Voltage Differential Signal (LVDS). A Bus Extension Module use Safety-Related PLC (Programmable Logic Controller), called POSAFE-Q (made by POSCO ICT), for handling many data (I/O) extension rack. A processor module of POSAFE-Q can control I/O Module installed another rack. This paper explains Bus Extension Module and Data transfer technology using LVDS. (author)

  11. Inversion of chromosome 7q22 and q36 as a sole abnormality presenting in myelodysplastic syndrome: a case report.

    Science.gov (United States)

    Kaneko, Hiroto; Shimura, Kazuho; Kuwahara, Saeko; Ohshiro, Muneo; Tsutsumi, Yasuhiko; Iwai, Toshiki; Horiike, Shigeo; Yokota, Shouhei; Ohkawara, Yasuo; Taniwaki, Masafumi

    2014-08-05

    Deletions of chromosome 7 are often detected in myelodysplastic syndrome. The most commonly deleted segments are clustered at band 7q22. A critical gene is therefore suggested to be located in this region. We report a patient with myelodysplastic syndrome whose marrow cells carried an inversion of 7q22 and q36 as a sole karyotypic abnormality. How this extremely rare chromosomal aberration contributes to the pathogenesis of myelodysplastic syndrome should be clarified by accumulating clinical data of such cases. A 74-year-old Japanese man presented with pancytopenia incidentally detected by routine medical check-up. His complete blood cell counts revealed that his white blood cells had decreased to 2100/mm3, neutrophils 940/mm3, red blood cells 320×104/mm3, hemoglobin 11.1g/dL, hematocrit 33.1%, and platelets 12.6×104/mm3. Bone marrow examination showed normal cellularity with nucleated cells of 9.4×104/mm3. The proportion of blasts was 4%. A morphological examination showed only basophilic stippling of erythroblasts which was seen as dysplasia. According to World Health Organization classification, the diagnosis was myelodysplastic syndrome-u. Karyotypic analysis showed 46,XY,inv(7)(q22q36) in all of 20 metaphases examined. Additional analysis revealed the karyotype of his lymphocytes was 46,XY. He is asymptomatic and cytopenia has slowly progressed. To the best of our knowledge, this karyotype from a clinical sample of de novo malignancies has never been documented although the identical karyotype from secondary myelodysplastic syndrome was reported. Despite the extremely low frequency, inversion of 7q22 appears to play a crucial role for myelodysplastic syndrome in this patient.

  12. q-Power function over q-commuting variables and deformed XXX, XXZ chains

    International Nuclear Information System (INIS)

    Khoroshkin, S.M.; Stolin, A.A.; Tolstoy, V.N.

    2001-01-01

    Certain functional identifies for the Gauss q-power function of a sum of q-commuting variables are found. Then these identifies are used to obtain two-parameter twists of the quantum affine algebra U q (sl 2 ) and of the Yangian Y(sl 2 ). The corresponding deformed trigonometric and rational quantum R matrices, which then are used in the computation of deformed XXX and XXZ Hamiltonians [ru

  13. "ON ALGEBRAIC DECODING OF Q-ARY REED-MULLER AND PRODUCT REED-SOLOMON CODES"

    Energy Technology Data Exchange (ETDEWEB)

    SANTHI, NANDAKISHORE [Los Alamos National Laboratory

    2007-01-22

    We consider a list decoding algorithm recently proposed by Pellikaan-Wu for q-ary Reed-Muller codes RM{sub q}({ell}, m, n) of length n {le} q{sup m} when {ell} {le} q. A simple and easily accessible correctness proof is given which shows that this algorithm achieves a relative error-correction radius of {tau} {le} (1-{radical}{ell}q{sup m-1}/n). This is an improvement over the proof using one-point Algebraic-Geometric decoding method given in. The described algorithm can be adapted to decode product Reed-Solomon codes. We then propose a new low complexity recursive aJgebraic decoding algorithm for product Reed-Solomon codes and Reed-Muller codes. This algorithm achieves a relative error correction radius of {tau} {le} {Pi}{sub i=1}{sup m} (1 - {radical}k{sub i}/q). This algorithm is then proved to outperform the Pellikaan-Wu algorithm in both complexity and error correction radius over a wide range of code rates.

  14. Economic significance of Q for mirror reactors: combinations of Q and M which look promising

    International Nuclear Information System (INIS)

    Werner, R.W.

    1978-01-01

    This term Q is the ratio of the fusion powder produced to the power input. It is a driven device. Q is truly the success parameter for mirrors--widely discussed but not succinctly specified as to required value. The problem is that Q can be treated as a subjective parameter--there are many milestone Qs; for scientific demonstration, for breakeven power, etc. Yet for a successful reactor, there is only one Q and that is the Q which produces mirror fusion power at the busbar that is less than the cost of delivered power in mills/kwhr by other means. We call this Q/sub PRACTICAL/ and believe there is a convincing argument that says this Q/sub PRACTICAL/ can be about 5.0 even assuming modest efficiencies for system components. A direct convertor is necessary. If the direct convertor were deleted, a Q/sub PRACTICAL/ of approximately 7.5 would be required. If we wish to soften the value of Q further, then the technical logic for the fusion fission hybrid is very powerful. With the hybrid a Q/sub PRACTICAL/ of 1.5 to 2.0 appears to be a very reasonable value. The key in being able to specify values of Q/sub PRACTICAL/ lies in economically comparing the capital cost of fusion power to the sum of the capital cost and the present value of all the fuel costs for the competitive fuel intensive plants

  15. Q-profiles in JET

    International Nuclear Information System (INIS)

    Gill, R.D.; Edwards, A.W.; Keegan, B.; Lazzaro, E.; O'Rourke, J.; Weller, A.; Zasche, D.

    1989-01-01

    Tokamak q-profiles play a central role in the determination of plasma stability and q(r) towards the plasma centre is particularly important for the sawtooth instability. On JET, q(r) has been determined from magnetic measurements and Faraday rotation. Further information about the position of the q=1 surface has been found from the sawtooth inversion radius, the position of the snake and the resonance effect observed on visible light and X-ray emission during pellet injection. In addition the shear at the q=1 surface has been measured from pellet ablation. This result is supported by the movement of the snake caused by a sawtooth crash. A summary of these data will be made after presenting the new results from pellet ablation. (author) 5 refs., 8 figs

  16. Compact Q-balls

    Energy Technology Data Exchange (ETDEWEB)

    Bazeia, D., E-mail: bazeia@fisica.ufpb.br [Departamento de Física, Universidade Federal da Paraíba, 58051-970 João Pessoa, PB (Brazil); Losano, L.; Marques, M.A. [Departamento de Física, Universidade Federal da Paraíba, 58051-970 João Pessoa, PB (Brazil); Menezes, R. [Departamento de Ciências Exatas, Universidade Federal da Paraíba, 58297-000 Rio Tinto, PB (Brazil); Departamento de Física, Universidade Federal de Campina Grande, 58109-970 Campina Grande, PB (Brazil); Rocha, R. da [Centro de Matemática, Computação e Cognição, Universidade Federal do ABC, 09210-580 Santo André (Brazil)

    2016-07-10

    In this work we deal with non-topological solutions of the Q-ball type in two space–time dimensions, in models described by a single complex scalar field that engenders global symmetry. The main novelty is the presence of stable Q-balls solutions that live in a compact interval of the real line and appear from a family of models controlled by two distinct parameters. We find analytical solutions and study their charge and energy, and show how to control the parameters to make the Q-balls classically and quantum mechanically stable.

  17. Development of Safety Grade PLC (POSAFE-Q) and Performance Test Results

    International Nuclear Information System (INIS)

    Kim, Chang Hwoi; Park, Won Man; Choi, Jong Gyun; Lee, Dong Young; No, Young Hun; Song, Seung Hwan

    2006-01-01

    The safety grade PLC (POSAFE-Q) is being developed in the Korea Nuclear Instrumentation and Control System (KNICS) R and D project. The PLC satisfies Safety Class 1E, Quality Class 1, and Seismic Category I. The software such as the RTOS and firmware are being developed according to the safety critical software life cycle. Especially, the formal method is applied to design the SRS (Software Requirement Spec.) and the SDS (Software Design Specification.) to be error-free. The POSAFE-Q has several modules such as processor module, input and output modules, communication modules, redundant processor module, redundant power modules, etc,. To verify the function and performance, several tests such as CT, IT and ST were performed. And also, the equipment qualification test for environment, EMI and EMC, and seismic ware performed. All tests are satisfied with the requirements and specification for safety grade PLC, and the criteria for safety system in nuclear power plants

  18. Development of Safety Grade PLC (POSAFE-Q) and Performance Test Results

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Chang Hwoi; Park, Won Man; Choi, Jong Gyun; Lee, Dong Young [Korea Atomic Energy Research Institute, Taejon (Korea, Republic of); No, Young Hun; Song, Seung Hwan [POSCON, Seoul (Korea, Republic of)

    2006-07-01

    The safety grade PLC (POSAFE-Q) is being developed in the Korea Nuclear Instrumentation and Control System (KNICS) R and D project. The PLC satisfies Safety Class 1E, Quality Class 1, and Seismic Category I. The software such as the RTOS and firmware are being developed according to the safety critical software life cycle. Especially, the formal method is applied to design the SRS (Software Requirement Spec.) and the SDS (Software Design Specification.) to be error-free. The POSAFE-Q has several modules such as processor module, input and output modules, communication modules, redundant processor module, redundant power modules, etc,. To verify the function and performance, several tests such as CT, IT and ST were performed. And also, the equipment qualification test for environment, EMI and EMC, and seismic ware performed. All tests are satisfied with the requirements and specification for safety grade PLC, and the criteria for safety system in nuclear power plants.

  19. Bioavailability enhancement of coenzyme Q10: an extensive review of patents.

    Science.gov (United States)

    Beg, Sarwar; Javed, Shamama; Kohli, Kanchan

    2010-11-01

    Coenzyme Q10 (CoQ10) is a major antioxidant principle found in human body which plays a vital role in maintaining several biochemical pathways of body. It acts as a potential mediator in transferring electrons in oxidoreductive reactions of electron transport chain. Chemically, it is a basic quinone containing moiety having a large and high molecular weight structure. Deficiency of this in body leads to several potential disorders like dysfunctions in cellular energetics, neurological degeneration, higher oxidative stress induced damage, breast cancer etc. The high molecular weight and lipophilicity of CoQ10 makes it poorly water soluble and consequently leads to low systemic availability. Several advancements have been made to enhance the bioavailability of CoQ10 using various approaches like size reduction, solubility enhancement (by solid dispersion, prodrug, complexation, ionization) and use of novel drug carriers such as liposomes, microspheres, nanoparticles, nanoemulsions and self-emulsifying system. The primary objective of the present review is to assemble patents representing the various approaches used for enhancement of CoQ10 bioavailability.

  20. Die soeke na die betekenis van Q: Inleidende opmerkings oor die geskiedenis van Q-navorsing

    Directory of Open Access Journals (Sweden)

    Gerhard Nel

    2003-10-01

    According to the two source-theory, large parts of the material in Matthew and Luke which show conformity and which are not found in Mark, point to the existence of a source which comprises sayings of Jesus and reminds one of the typical wisdom material in the Old Testament. In this paper a few introductory remarks are made on the history of the research done in respect of this source, known as Q. The questions regarding the actual existence and origin of Q are briefly discussed in the first part of the paper. Four aspects of Q research are addressed: Q is a document which shows its own integrity; the distinction between tradition and redaction in Q; stratifications and phases in the development of Q; the wisdom character of the material in Q.

  1. Coenzyme Q Metabolism Is Disturbed in High Fat Diet-Induced Non Alcoholic Fatty Liver Disease in Rats

    Directory of Open Access Journals (Sweden)

    Kathleen M Botham

    2012-02-01

    Full Text Available Oxidative stress is believed to be a major contributory factor in the development of non alcoholic fatty liver disease (NAFLD, the most common liver disorder worldwide. In this study, the effects of high fat diet-induced NAFLD on Coenzyme Q (CoQ metabolism and plasma oxidative stress markers in rats were investigated. Rats were fed a standard low fat diet (control or a high fat diet (57% metabolizable energy as fat for 18 weeks. The concentrations of total (reduced + oxidized CoQ9 were increased by > 2 fold in the plasma of animals fed the high fat diet, while those of total CoQ10 were unchanged. Reduced CoQ levels were raised, but oxidized CoQ levels were not, thus the proportion in the reduced form was increased by about 75%. A higher percentage of plasma CoQ9 as compared to CoQ10 was in the reduced form in both control and high fat fed rats. Plasma protein thiol (SH levels were decreased in the high fat-fed rats as compared to the control group, but concentrations of lipid hydroperoxides and low density lipoprotein (LDL conjugated dienes were unchanged. These results indicate that high fat diet-induced NAFLD in rats is associated with altered CoQ metabolism and increased protein, but not lipid, oxidative stress.

  2. Japanese version of the ALS-FTD-Questionnaire (ALS-FTD-Q-J).

    Science.gov (United States)

    Watanabe, Yasuhiro; Beeldman, Emma; Raaphorst, Joost; Izumi, Yuishin; Yoshino, Hiide; Masuda, Michihito; Atsuta, Naoki; Ito, Satoru; Adachi, Tadashi; Adachi, Yoshiki; Yokota, Osamu; Oda, Masaya; Hanashima, Ritsuko; Ogino, Mieko; Ichikawa, Hiroo; Hasegawa, Kazuko; Kimura, Hideki; Shimizu, Toshio; Aiba, Ikuko; Yabe, Hayato; Kanba, Makoto; Kusumi, Kimiyoshi; Aoki, Tetsuya; Hiroe, Yu; Watanabe, Hirohisa; Nishiyama, Kazutoshi; Nomoto, Masahiro; Sobue, Gen; Nakashima, Kenji

    2016-08-15

    Amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD) share common clinical, genetic and neuropathological features. Some ALS patients have behavioral/personality changes, which could result in significant obstacles in the care provided by family members and caregivers. An easy screening tool would contribute greatly to the evaluation of these symptoms. We translated the ALS-FTD-Questionnaire, developed in the Netherlands, into Japanese (ALS-FTD-Q-J) and examined the clinimetric properties (internal consistency, construct and clinical validity). Patients with ALS and/or behavioral variant FTD (bvFTD) were evaluated alongside healthy controls in this multicenter study. All ALS patients, regardless of bvFTD status, were further evaluated by the frontal behavioral inventory (FBI) and for frontal/executive function, cognition, anxiety/depression, and motor functions. Data from 146 subjects were analyzed: ALS (92), ALS-bvFTD (6), bvFTD (16), and healthy controls (32). The internal consistency of the ALS-FTD-Q-J was good (Cronbach α=0.92). The ALS-FTD-Q-J showed construct validity as it exhibited a high correlation with the FBI (r=0.79). However, correlations were moderate with anxiety/depression and low with cognitive scales, in contrast to the original report, i.e. a moderate correlation with cognition and a low correlation with anxiety/depression. The ALS-FTD-Q-J discriminated ALS patients from (ALS-)bvFTD patients and controls. Thus, the ALS-FTD-Q-J is useful for evaluating Japanese ALS/FTD patients. Copyright © 2016 Elsevier B.V. All rights reserved.

  3. Heart defects and other features of the 22q11 distal deletion syndrome

    DEFF Research Database (Denmark)

    Fagerberg, Christina Ringmann; Graakjaer, Jesper; Heinl, Ulrike D

    2013-01-01

    patients with 22q11 distal deletions, of whom two have complex congenital heart malformation, thus broadening the phenotypic spectrum. We compare cardiac malformations reported in 22q11 distal deletion to those reported in the common 22q11 deletion syndrome. We also review the literature for patients...... with 22q11 distal deletions, and discuss the possible roles of haploinsufficiency of the MAPK1 gene. We find the most frequent features in 22q11 distal deletion to be developmental delay or learning disability, short stature, microcephalus, premature birth with low birth weight, and congenital heart...... malformation ranging from minor anomalies to complex malformations. Behavioral problems are also seen in a substantial portion of patients. The following dysmorphic features are relatively common: smooth philtrum, abnormally structured ears, cleft palate/bifid uvula, micro-/retrognathia, upslanting palpebral...

  4. q-deformed Minkowski space

    International Nuclear Information System (INIS)

    Ogievetsky, O.; Pillin, M.; Schmidke, W.B.; Wess, J.; Zumino, B.

    1993-01-01

    In this lecture I discuss the algebraic structure of a q-deformed four-vector space. It serves as a good example of quantizing Minkowski space. To give a physical interpretation of such a quantized Minkowski space we construct the Hilbert space representation and find that the relevant time and space operators have a discrete spectrum. Thus the q-deformed Minkowski space has a lattice structure. Nevertheless this lattice structure is compatible with the operation of q-deformed Lorentz transformations. The generators of the q-deformed Lorentz group can be represented as linear operators in the same Hilbert space. (orig.)

  5. Q2 anti Q2 states with relatively narrow widths

    International Nuclear Information System (INIS)

    Ono, Seiji.

    1978-09-01

    Using the mass formulas which correctly predict the mass of mesons and baryons the mass of diquark states is computed. From this mass spectrum the existance of the observed narrow baryonia and wide baryonia can be naturally understood. Other relatively narrow Q 2 anti Q 2 states are predicted to exist. (orig.) [de

  6. Review of the Frontier Workshop and Q-slope results

    Energy Technology Data Exchange (ETDEWEB)

    Gianluigi Ciovati

    2005-09-20

    Over the last few years, significant progress has been made to produce field emission free niobium surfaces. Nowadays, the major limitation towards achieving the critical field in radio-frequency (rf) superconducting cavities made of bulk niobium of high purity is represented by the so-called ''high field Q-slope'' or ''Q-drop''. This phenomenon is characterized by a sharp decrease of the cavity quality factor, in absence of field emission, starting at a peak surface magnetic field of the order of 100 mT. It has been observed that these losses are usually reduced by a low-temperature ''in-situ'' baking, typically at 100-120 C for 24-48 h. Several models have been proposed to explain the high field Q-slope and many experiments have been conducted in different laboratories to validate such models. A three-day workshop was held in Argonne in September 2004 to present and discuss experimental and theoretical results on the present limitations of superconducting rf cavities. In this paper, we will focus on the high field Q-slope by reviewing the results presented at the workshop along with other experimental data. In order to explain the Q-drop and the baking effect we will discuss an improved version of the oxygen diffusion model.

  7. Analytic derivation of the leading-order gluon distribution function G(x,Q2)=xg(x,Q2) from the proton structure function F2p(x,Q2)

    International Nuclear Information System (INIS)

    Block, Martin M.; Durand, Loyal; McKay, Douglas W.

    2008-01-01

    We derive a second-order linear differential equation for the leading-order gluon distribution function G(x,Q 2 )=xg(x,Q 2 ) which determines G(x,Q 2 ) directly from the proton structure function F 2 p (x,Q 2 ). This equation is derived from the leading-order evolution equation for F 2 p (x,Q 2 ), and does not require knowledge of either the individual quark distributions or the gluon evolution equation. Given an analytic expression that successfully reproduces the known experimental data for F 2 p (x,Q 2 ) in a domain x min (Q 2 )≤x≤x max (Q 2 ), Q min 2 ≤Q 2 ≤Q max 2 of the Bjorken variable x and the virtuality Q 2 in deep inelastic scattering, G(x,Q 2 ) is uniquely determined in the same domain. We give the general solution and illustrate the method using the recently proposed Froissart-bound-type parametrization of F 2 p (x,Q 2 ) of E. L. Berger, M. M. Block and C.-I. Tan [Phys. Rev. Lett. 98, 242001 (2007)]. Existing leading-order gluon distributions based on power-law descriptions of individual parton distributions agree roughly with the new distributions for x > or approx. 10 -3 as they should, but are much larger for x -3 .

  8. A first case of primary amenorrhea with i(X(qter---q10::---qter, rob(13;14(q10;q10, inv(9(p13q33 karyotype

    Directory of Open Access Journals (Sweden)

    Seema Korgaonkar

    2011-01-01

    Full Text Available Primary amenorrhea (PA refers to the absence of menarche by the age of 16-18 years although secondary sexual characters are developed. PA occurs in 1-3% of women in the reproductive age group. Various factors such as anatomical, genetic and hormonal factors reported to influence PA. We report triple chromosomal abnormalities of rob(13;14(q10;q10,inv(9(p13q33, i(Xq(qter---q10::---qter in a case of PA and short stature. Though proband has multiple chromosome aberrations, genotypic effect of only i(Xq is evident as proband has PA and short stature. The rob(13;14 and inv(9, which are paternally derived may have role in later reproductive age. Therefore, chromosomal analysis is essential in such cases for the accurate diagnosis and management of the disease.

  9. Viability qPCR, a new tool for Legionella risk management.

    Science.gov (United States)

    Lizana, X; López, A; Benito, S; Agustí, G; Ríos, M; Piqué, N; Marqués, A M; Codony, F

    2017-11-01

    Viability quantitative Polymerase Chain Reaction (v-qPCR) is a recent analytical approach for only detecting live microorganisms by DNA amplification-based methods This approach is based on the use of a reagent that irreversibly fixes dead cells DNA. In this study, we evaluate the utility of v-qPCR versus culture method for Legionellosis risk management. The present study was performed using 116 real samples. Water samples were simultaneously analysed by culture, v-qPCR and qPCR methods. Results were compared by means of a non-parametric test. In 11.6% of samples using both methods (culture method and v-qPCR) results were positive, in 50.0% of samples both methods gave rise to negative results. As expected, equivalence between methods was not observed in all cases, as in 32.1% of samples positive results were obtained by v-qPCR and all of them gave rise to negative results by culture. Only in 6.3% of samples, with very low Legionella levels, was culture positive and v-qPCR negative. In 3.5% of samples, overgrowth of other bacteria did not allow performing the culture. When comparing both methods, significant differences between culture and v-qPCR were in the samples belonging to the cooling towers-evaporative condensers group. The v-qPCR method detected greater presence and obtained higher concentrations of Legionella spp. (p<0.001). Otherwise, no significant differences between methods were found in the rest of the groups. The v-qPCR method can be used as a quick tool to evaluate Legionellosis risk, especially in cooling towers-evaporative condensers, where this technique can detect higher levels than culture. The combined interpretation of PCR results along with the ratio of live cells is proposed as a tool for understanding the sample context and estimating the Legionellosis risk potential according to 4 levels of hierarchy. Copyright © 2017 Elsevier GmbH. All rights reserved.

  10. The Q{sup p}{sub Weak} experiment

    Energy Technology Data Exchange (ETDEWEB)

    Androic, D. [University of Zagreb (Croatia); Armstrong, D. S. [The College of William and Mary (United States); Asaturyan, A. [Yerevan Physics Institute (Armenia); Averett, T. [The College of William and Mary (United States); Balewski, J. [Massachusetts Institute of Technology (United States); Beaufait, J. [Thomas Jefferson National Accelerator Facility (United States); Beminiwattha, R. S. [Ohio University (United States); Benesch, J. [Thomas Jefferson National Accelerator Facility (United States); Benmokhtar, F. [Duquesne University (United States); Birchall, J. [University of Manitoba (Canada); Carlini, R. D.; Cornejo, J. C. [The College of William and Mary (United States); Covrig, S. [Thomas Jefferson National Accelerator Facility (United States); Dalton, M. M. [University of Virginia (United States); Davis, C. A. [TRIUMF (United States); Deconinck, W. [The College of William and Mary (United States); Diefenbach, J. [Hampton University (United States); Dow, K. [Massachusetts Institute of Technology (United States); Dowd, J. F. [The College of William and Mary (United States); Dunne, J. A. [Mississippi State University (United States); and others

    2013-03-15

    In May 2012, the Q{sup p}{sub Weak} collaboration completed a two year measurement program to determine the weak charge of the proton Q{sub W}{sup p} = ( 1 - 4sin{sup 2}{theta}{sub W}) at the Thomas Jefferson National Accelerator Facility (TJNAF). The experiment was designed to produce a 4.0 % measurement of the weak charge, via a 2.5 % measurement of the parity violating asymmetry in the number of elastically scattered 1.165 GeV electrons from protons, at forward angles. At the proposed precision, the experiment would produce a 0.3 % measurement of the weak mixing angle at a momentum transfer of Q{sup 2} = 0.026 GeV{sup 2}, making it the most precise stand alone measurement of the weak mixing angle at low momentum transfer. In combination with other parity measurements, Q{sup p}{sub Weak} will also provide a high precision determination of the weak charges of the up and down quarks. At the proposed precision, a significant deviation from the Standard Model prediction could be a signal of new physics at mass scales up to Asymptotically-Equal-To 6 TeV, whereas agreement would place new and significant constraints on possible Standard Model extensions at mass scales up to Asymptotically-Equal-To 2 TeV. This paper provides an overview of the physics and the experiment, as well as a brief look at some preliminary diagnostic and analysis data.

  11. Comprehensive review of the duplication 3q syndrome and report of a patient with Currarino syndrome and de novo duplication 3q26.32-q27.2.

    Science.gov (United States)

    Dworschak, G C; Crétolle, C; Hilger, A; Engels, H; Korsch, E; Reutter, H; Ludwig, M

    2017-05-01

    Partial duplications of the long arm of chromosome 3, dup(3q), are a rare but well-described condition, sharing features of Cornelia de Lange syndrome. Around two thirds of cases are derived from unbalanced translocations, whereas pure dup(3q) have rarely been reported. Here, we provide an extensive review of the literature on dup(3q). This search revealed several patients with caudal malformations and anomalies, suggesting that caudal malformations or anomalies represent an inherent phenotypic feature of dup(3q). In this context, we report a patient with a pure de novo duplication 3q26.32-q27.2. The patient had the clinical diagnosis of Currarino syndrome (CS) (characterized by the triad of sacral anomalies, anorectal malformations and a presacral mass) and additional features, frequently detected in patients with a dup(3q). Mutations within the MNX1 gene were found to be causative in CS but no MNX1 mutation could be detected in our patient. Our comprehensive search for candidate genes located in the critical region of the duplication 3q syndrome, 3q26.3-q27, revealed a so far neglected phenotypic overlap of dup(3q) and the Pierpont syndrome, associated with a mutation of the TBL1XR1 gene on 3q26.32. © 2016 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

  12. A Quantitative Electrophysiological Biomarker of Duplication 15q11.2-q13.1 Syndrome.

    Directory of Open Access Journals (Sweden)

    Joel Frohlich

    Full Text Available Duplications of 15q11.2-q13.1 (Dup15q syndrome are highly penetrant for autism spectrum disorder (ASD. A distinct electrophysiological (EEG pattern characterized by excessive activity in the beta band has been noted in clinical reports. We asked whether EEG power in the beta band, as well as in other frequency bands, distinguished children with Dup15q syndrome from those with non-syndromic ASD and then examined the clinical correlates of this electrophysiological biomarker in Dup15q syndrome.In the first study, we recorded spontaneous EEG from children with Dup15q syndrome (n = 11, age-and-IQ-matched children with ASD (n = 10 and age-matched typically developing (TD children (n = 9 and computed relative power in 6 frequency bands for 9 regions of interest (ROIs. Group comparisons were made using a repeated measures analysis of variance. In the second study, we recorded spontaneous EEG from a larger cohort of individuals with Dup15q syndrome (n = 27 across two sites and examined age, epilepsy, and duplication type as predictors of beta power using simple linear regressions.In the first study, spontaneous beta1 (12-20 Hz and beta2 (20-30 Hz power were significantly higher in Dup15q syndrome compared with both comparison groups, while delta (1-4 Hz was significantly lower than both comparison groups. Effect sizes in all three frequency bands were large (|d| > 1. In the second study, we found that beta2 power was significantly related to epilepsy diagnosis in Dup15q syndrome.Here, we have identified an electrophysiological biomarker of Dup15q syndrome that may facilitate clinical stratification, treatment monitoring, and measurement of target engagement for future clinical trials. Future work will investigate the genetic and neural underpinnings of this electrophysiological signature as well as the functional consequences of excessive beta oscillations in Dup15q syndrome.

  13. Linear q-nonuniform difference equations

    International Nuclear Information System (INIS)

    Bangerezako, Gaspard

    2010-01-01

    We introduce basic concepts of q-nonuniform differentiation and integration and study linear q-nonuniform difference equations and systems, as well as their application in q-nonuniform difference linear control systems. (author)

  14. Distinctive phenotype in 9 patients with deletion of chromosome 1q24-q25.

    Science.gov (United States)

    Burkardt, Deepika D'Cunha; Rosenfeld, Jill A; Helgeson, Maria L; Angle, Brad; Banks, Valerie; Smith, Wendy E; Gripp, Karen W; Moline, Jessica; Moran, Rocio T; Niyazov, Dmitriy M; Stevens, Cathy A; Zackai, Elaine; Lebel, Robert Roger; Ashley, Douglas G; Kramer, Nancy; Lachman, Ralph S; Graham, John M

    2011-06-01

    Reports of individuals with deletions of 1q24→q25 share common features of prenatal onset growth deficiency, microcephaly, small hands and feet, dysmorphic face and severe cognitive deficits. We report nine individuals with 1q24q25 deletions, who show distinctive features of a clinically recognizable 1q24q25 microdeletion syndrome: prenatal-onset microcephaly and proportionate growth deficiency, severe cognitive disability, small hands and feet with distinctive brachydactyly, single transverse palmar flexion creases, fifth finger clinodactyly and distinctive facial features: upper eyelid fullness, small ears, short nose with bulbous nasal tip, tented upper lip, and micrognathia. Radiographs demonstrate disharmonic osseous maturation with markedly delayed bone age. Occasional features include cleft lip and/or palate, cryptorchidism, brain and spinal cord defects, and seizures. Using oligonucleotide-based array comparative genomic hybridization, we defined the critical deletion region as 1.9 Mb at 1q24.3q25.1 (chr1: 170,135,865-172,099,327, hg18 coordinates), containing 13 genes and including CENPL, which encodes centromeric protein L, a protein essential for proper kinetochore function and mitotic progression. The growth deficiency in this syndrome is similar to what is seen in other types of primordial short stature with microcephaly, such as Majewski osteodysplastic primordial dwarfism, type II (MOPD2) and Seckel syndrome, which result from loss-of-function mutations in genes coding for centrosomal proteins. DNM3 is also in the deleted region and expressed in the brain, where it participates in the Shank-Homer complex and increases synaptic strength. Therefore, DNM3 is a candidate for the cognitive disability, and CENPL is a candidate for growth deficiency in this 1q24q25 microdeletion syndrome. Copyright © 2011 Wiley-Liss, Inc.

  15. Chemistry and Molecular Dynamics Simulations of Heme b-HemQ and Coproheme-HemQ.

    Science.gov (United States)

    Hofbauer, Stefan; Dalla Sega, Marco; Scheiblbrandner, Stefan; Jandova, Zuzana; Schaffner, Irene; Mlynek, Georg; Djinović-Carugo, Kristina; Battistuzzi, Gianantonio; Furtmüller, Paul G; Oostenbrink, Chris; Obinger, Christian

    2016-09-27

    Recently, a novel pathway for heme b biosynthesis in Gram-positive bacteria has been proposed. The final poorly understood step is catalyzed by an enzyme called HemQ and includes two decarboxylation reactions leading from coproheme to heme b. Coproheme has been suggested to act as both substrate and redox active cofactor in this reaction. In the study presented here, we focus on HemQs from Listeria monocytogenes (LmHemQ) and Staphylococcus aureus (SaHemQ) recombinantly produced as apoproteins in Escherichia coli. We demonstrate the rapid and two-phase uptake of coproheme by both apo forms and the significant differences in thermal stability of the apo forms, coproheme-HemQ and heme b-HemQ. Reduction of ferric high-spin coproheme-HemQ to the ferrous form is shown to be enthalpically favored but entropically disfavored with standard reduction potentials of -205 ± 3 mV for LmHemQ and -207 ± 3 mV for SaHemQ versus the standard hydrogen electrode at pH 7.0. Redox thermodynamics suggests the presence of a pronounced H-bonding network and restricted solvent mobility in the heme cavity. Binding of cyanide to the sixth coproheme position is monophasic but relatively slow (∼1 × 10(4) M(-1) s(-1)). On the basis of the available structures of apo-HemQ and modeling of both loaded forms, molecular dynamics simulation allowed analysis of the interaction of coproheme and heme b with the protein as well as the role of the flexibility at the proximal heme cavity and the substrate access channel for coproheme binding and heme b release. Obtained data are discussed with respect to the proposed function of HemQ in monoderm bacteria.

  16. Report on the Test and Evaluation of the Kinemetrics/Quanterra Q730B Borehole Digitizers; TOPICAL

    International Nuclear Information System (INIS)

    KROMER, RICHARD P.; MCDONALD, TIMOTHY S.

    1999-01-01

    Sandia National Laboratories has tested and evaluated the Kinemetrics/Quanterra Q730B-bb (broadband) and Q730B-sp (short period) borehole installation remote digitizers. The test results included in this report were for response to static and dynamic input signals, seismic application performance, data time-tag accuracy, and reference signal generator (calibrator) performance. Most test methodologies used were based on IEEE Standards 1057 for Digitizing Waveform Recorders and P1241 (Preliminary Draft) for Analog to Digital Converters; others were designed by Sandia specifically for seismic application evaluation and for supplementary criteria not addressed in the IEEE standards. When appropriate, test instrumentation calibration is traceable to the National Institute for Standards Technology (NIST)

  17. Direct Comparison of 19F qNMR and 1H qNMR by Characterizing Atorvastatin Calcium Content

    Directory of Open Access Journals (Sweden)

    Yang Liu

    2016-01-01

    Full Text Available Quantitative nuclear magnetic resonance (qNMR is a powerful tool in measuring drug content because of its high speed, sensitivity, and precision. Most of the reports were based on proton qNMR (1H qNMR and only a few fluorine qNMR (19F qNMR were reported. No research has been conducted to directly compare the advantage and disadvantage between these two methods. In the present study, both 19F and 1H qNMR were performed to characterize the content of atorvastatin calcium with the same internal standard. Linearity, precision, and results from two methods were compared. Results showed that 19F qNMR has similar precision and sensitivity to 1H qNMR. Both methods generate similar results compared to mass balance method. Major advantage from 19F qNMR is that the analyte signal is with less or no interference from impurities. 19F qNMR is an excellent approach to quantify fluorine-containing analytes.

  18. Q-bank phytoplasma database

    DEFF Research Database (Denmark)

    Contaldo, Nicoletta; Bertaccini, Assunta; Nicolaisen, Mogens

    2014-01-01

    The setting of the Q-Bank database free available on line for quarantine phytoplasma and also for general phytoplasma identification is described. The tool was developed in the frame of the EU-FP7 project Qbol and is linked with a new project Q-collect in order to made widely available the identi......The setting of the Q-Bank database free available on line for quarantine phytoplasma and also for general phytoplasma identification is described. The tool was developed in the frame of the EU-FP7 project Qbol and is linked with a new project Q-collect in order to made widely available...

  19. A q-deformed nonlinear map

    International Nuclear Information System (INIS)

    Jaganathan, Ramaswamy; Sinha, Sudeshna

    2005-01-01

    A scheme of q-deformation of nonlinear maps is introduced. As a specific example, a q-deformation procedure related to the Tsallis q-exponential function is applied to the logistic map. Compared to the canonical logistic map, the resulting family of q-logistic maps is shown to have a wider spectrum of interesting behaviours, including the co-existence of attractors-a phenomenon rare in one-dimensional maps

  20. Introduction of helical computed tomography affects patient selection for V/Q lung scan

    International Nuclear Information System (INIS)

    Zettinig, G.; Baudrexel, S.; Leitha, Th.

    2002-01-01

    Aim: Retrospective analysis for determination of the effect of helical computed tomography (HCT) on utilization of V/Q lung scanning to diagnose pulmonary embolism (PE) in a large general hospital. Methods: A total number of 2676 V/Q scans of in- and out-patients referred to our department between March 1992 and December 1998 and between April 1997 and December 1998 were analyzed by an identical group of nuclear physicians. Results: Neither the total number of annually performed V/Q scans (446 ± 135) nor the mean age of patients (56 years ± 17) changed significantly since the introduction of HCT. However, the referral pattern was different. The percentage of patients with high and intermediate probability for PE decreased significantly from 15.2% to 9.4% (p <0.01) and from 10.2% to 7.3% (p <0.05), respectively. Low probability scans significantly increased from 37.8% to 42.7% (p <0.05). The percentage of normal scans did not change significantly, however, there was a highly significant increase summarizing patients with normal and low probability scans (74.6% to 83.3%; p <0.01). Conclusion: The introduction of HCT affected the selection of patients referred for V/Q lung scanning since V/Q scanning was primarily used to exclude rather to confirm PE. (orig.)

  1. Fabrication of Low-Noise TES Arrays for the SAFARI Instrument on SPICA

    Science.gov (United States)

    Ridder, M. L.; Khosropanah, P.; Hijmering, R. A.; Suzuki, T.; Bruijn, M. P.; Hoevers, H. F. C.; Gao, J. R.; Zuiddam, M. R.

    2016-07-01

    Ultra-low-noise transition edge sensors (TES) with noise equivalent power lower than 2 × 10^{-19} W/Hz^{1/2 } have been fabricated by SRON, which meet the sensitivity requirements for the far-infrared SAFARI instrument on space infrared telescope for cosmology and astrophysics. Our TES detector is based on a titanium/gold (Ti/Au) thermistor on a silicon nitride (SiN) island. The island is thermally linked with SiN legs to a silicon support structure at the bath temperature. The SiN legs are very thin (250 nm), narrow (500 nm), and long (above 300 {\\upmu } m); these dimensions are needed in leg-isolated bolometers to achieve the required level of sensitivity. In this paper, we describe the latest fabrication process for our TES bolometers with improved sensitivity.

  2. KFM 01A. Q-logging

    International Nuclear Information System (INIS)

    Barton, Nick

    2003-03-01

    The first Forsmark potential repository site borehole KFM 01A provided core from 101.8 to 1000.7 m depth. This was independently Q-logged during a two-day period (19th-20th February, 2003), without access to BORMAP results or regional jointing frequencies or orientations. The Q-logging was intended to be an independent check for subsequent BORMAP-derived Q-parameter estimation. The Q-logging was accomplished using the manually-recorded 'histogram method' which allows the logger to enter Q-parameter ranges and depths directly into the appropriate histograms, which facilitates subsequent data processing using Excel spreadsheets. Successive pairs of core boxes, which contain an average of 11 meters of core in ten rows, were the source of ten opinions of each of the six Q-parameters, giving a total of 4920 recordings of Q-parameter values for the 164 core boxes. Data processing was divided into several parts, with successively increasing detail. The report therefore contains Q-histograms for the whole core, for four identified fracture(d) zones combined as if one unit, and then for the whole core minus these fracture(d) zones. This background rock mass quality is subsequently divided into nine depth zones or slices, and trends of variation with depth are tabulated. The four identified fracture(d) zones, which are actually of reasonable quality, are also analysed separately, and similarities and subtle differences are discerned between them. The overall quality of this first core is very good to excellent, with Q(mean) of 48.4, and a most frequent Q-value of 100. The range of quality is from 2.1 to 2130, which is the complete upper half of the six order of magnitude Q scale. Even the relatively fracture(d) zones, representing some 13% of the 900 m cored, have a combined Q(mean) of 13.9 and a range of quality of 2.1 to 150

  3. q-deformed Brownian motion

    CERN Document Server

    Man'ko, V I

    1993-01-01

    Brownian motion may be embedded in the Fock space of bosonic free field in one dimension.Extending this correspondence to a family of creation and annihilation operators satisfying a q-deformed algebra, the notion of q-deformation is carried from the algebra to the domain of stochastic processes.The properties of q-deformed Brownian motion, in particular its non-Gaussian nature and cumulant structure,are established.

  4. Translation and cultural adaptation of the CLEFT-Q for use in Colombia, Chile, and Spain.

    Science.gov (United States)

    Tsangaris, Elena; Riff, Karen W Y Wong; Vargas, Federico; Aguilera, Mirta Palomares; Alarcón, Macarena Miranda; Cazalla, Asteria Albert; Thabane, Lehana; Thoma, Achilleas; Klassen, Anne F

    2017-11-28

    Cleft lip and/or palate (CL/P) is a common congenital craniofacial anomaly that may negatively affect an individual's appearance, health-related quality of life, or speech. In Spain, Colombia, and Chile the overall prevalence of CL/P ranges from 0.53 to 1.59 cases per 1000 live births. Currently, there is no patient-reported outcome (PRO) instrument that is specific for patients with CL/P. The CLEFT-Q is a new PRO instrument developed to measure outcomes of treatment in patients 8 to 29 years of age with CL/P. The aim of this study was to translate and culturally adapt the CLEFT-Q for use in Colombia, Chile, and Spain. The CLEFT-Q was translated from English to 3 Spanish language varieties (Colombian, Chilean, and Spanish (Spain)) and Catalan. Translation and cultural adaptation guidelines set forth by the International Society for Pharmacoeconomics and Outcomes Research were followed. The field- test version of the CLEFT-Q consisted of 13 scales (total 154 items) measuring appearance, health-related quality of life, and facial function. Forward translations revealed 10 (7%) items that were difficult to translate into Chilean, and back translations identified 34 (22%) and 21 (13%) items whose meaning differed from the English version in at least 1 of the 3 Spanish varieties and Catalan respectively. Twenty-one participants took part in cognitive debriefing interviews. Participants were recruited from plastic surgery centres in Bogotá, Colombia (n = 4), Santiago, Chile (n = 7), and Barcelona, Spain (n = 10). Most participants were males (n = 14, 67%) and were diagnosed with CL/P (n = 17, 81%). Participants reported difficulty understanding 1 item in the Colombian, 1 item in the Spanish (Spain), and 11 items from the Catalan version. Comparison of the 3 Spanish varieties revealed 61 (40%) of the 154 items whose wording differed across the 3 Spanish versions. Translation and cultural adaptation processes provided evidence of transferability of

  5. [Coenzyme Q10 (Q-ter) in treatment of functional voice disorders].

    Science.gov (United States)

    Sensini, M; Corvino, A; Passeri, L; Gallone, G O; Landolfo, V; Raimondo, L; Giordano, C

    2011-01-01

    Aim of this study was to evaluate the effectivness of Coenzyme Q-Ter and Vitamin A in functional voice disorders. Twenty two patients were treated with CoQ10-ter and vitamin A twice a day for ten days. A general otolaryngological/foniatric and logopedic examination were performed. Videolaringostroboscopy, GIRBAS, Voice Handicap Index questionnaire and Multi-Dimensional Voice analysis were carried out before and after treatment. In all patients an improvement was observed in almost all parameters considered after treatment. CoQ10-ter and Vitamin A risulted effective in treatment of patients with functional voice disorders (caused by vocal "malmenage" or "surmenage").

  6. Jets at low Q{sup 2} at HERA and radiation damage studies for silicon sensors for the XFEL

    Energy Technology Data Exchange (ETDEWEB)

    Perrey, Hanno

    2011-06-15

    In the first part this thesis, jet cross-sections were measured for inclusive jet, inclusive dijet, and inclusive trijet production at photon virtualities in the range of 10<Q{sup 2}<100 GeV{sup 2}. The data analyzed were recorded with the Zeus detector in the years 2004-2007 corresponding to an integrated luminosity of 296 pb{sup -1}. Events in neutral current deep inelastic scattering were selected in the above stated Q{sup 2} region for an inelasticity of 0.28 GeV and to have a pseudorapidity in the laboratory frame in the range of -1< {eta}{sub lab}<2.5. For the dijet and trijet samples, an additional requirement was imposed on the invariant dijet mass of M{sub jj}>20 GeV to avoid phase space regions where the fixed order calculations are sensitive to infrared divergences. The presented analysis is the first jet analysis at such low values of Q{sup 2} to exploit the full HERA-II ZEUS data set, and as such is performed at significant higher luminosities than previous publications. Overall, the next-to-leading order (NLO) calculations correctly predict the measured cross-sections within the uncertainties in all studied quantities and over most of the investigated regions of phase space, except in the pseudorapidity region close to the proton beam direction (''forward'' region) in inclusive jet production where the prediction is considerably below the data. The uncertainty of the NLO prediction, dominated by the uncertainty associated with the choice of the renormalization scale, is typically larger than the experimental uncertainty, which is for the most part dominated by the uncertainty of the jet energy scale. The large theoretical uncertainties indicate the need for calculations including higherorders. Such NNLO calculations will allow to fully

  7. Room Q data report: Test borehole data from April 1989 through November 1991

    International Nuclear Information System (INIS)

    Jensen, A.L.; Howard, C.L.; Jones, R.L.; Peterson, T.P.

    1993-03-01

    Pore-pressure and fluid-flow tests were performed in 15 boreholes drilled into the bedded evaporites of the Salado Formation from within the Waste Isolation Pilot Plant (WIPP). The tests measured fluid flow and pore pressure within the Salado. The boreholes were drilled into the previously undisturbed host rock around a proposed cylindrical test room, Room Q, located on the west side of the facility about 655 m below ground surface. The boreholes were about 23 m deep and ranged over 27.5 m of stratigraphy. They were completed and instrumented before excavation of Room Q. Tests were conducted in isolated zones at the end of each borehole. Three groups of 5 isolated zones extend above, below, and to the north of Room Q at increasing distances from the room axis. Measurements recorded before, during, and after the mining of the circular test room provided data about borehole closure, pressure, temperature, and brine seepage into the isolated zones. The effects of the circular excavation were recorded. This data report presents the data collected from the borehole test zones between April 25, 1989 and November 25, 1991. The report also describes test development, test equipment, and borehole drilling operations

  8. ν-Dimensional ideal quantum q-gas: Bose-Einstein condensation and λ-point transition

    International Nuclear Information System (INIS)

    R-Monteiro, M.; Roditi, I.; Rodrigues, L.M.C.S.

    1994-01-01

    The authors consider an ideal quantum q-gas in ν spatial dimensions and energy spectrum ω i αp α . Departing from the Hamiltonian H = ω[N], the authors study the effect of the deformation on thermodynamic functions and equation of state of that system. The virial expansion is obtained for the high temperature (or low density) regime. The critical temperature is higher than in non-deformed ideal gases. They show that Bose-Einstein condensation always exists (unless when ν/α = 1) for finite q but not for q = ∞. Employing numerical calculations and selecting for ν/α the values 3/2, 2 and 3, the authors show the critical temperature as a function of q, the specific heat C V and the chemical potential μ as functions of T/T c q for q = 1.05 and q= 4.5. C V exhibits a λ-point discontinuity in all cases, instead of the cusp singularity found in the usual ideal gas. The results indicate that physical systems which have quantum symmetries can exhibit Bose-Einstein condensation phenomenon, the critical temperature being favored by the deformation parameter

  9. Cellular telephone-based radiation detection instrument

    Science.gov (United States)

    Craig, William W [Pittsburg, CA; Labov, Simon E [Berkeley, CA

    2011-06-14

    A network of radiation detection instruments, each having a small solid state radiation sensor module integrated into a cellular phone for providing radiation detection data and analysis directly to a user. The sensor module includes a solid-state crystal bonded to an ASIC readout providing a low cost, low power, light weight compact instrument to detect and measure radiation energies in the local ambient radiation field. In particular, the photon energy, time of event, and location of the detection instrument at the time of detection is recorded for real time transmission to a central data collection/analysis system. The collected data from the entire network of radiation detection instruments are combined by intelligent correlation/analysis algorithms which map the background radiation and detect, identify and track radiation anomalies in the region.

  10. Wave-equation Q tomography

    KAUST Repository

    Dutta, Gaurav

    2016-10-12

    Strong subsurface attenuation leads to distortion of amplitudes and phases of seismic waves propagating inside the earth. The amplitude and the dispersion losses from attenuation are often compensated for during prestack depth migration. However, most attenuation compensation or Qcompensation migration algorithms require an estimate of the background Q model. We have developed a wave-equation gradient optimization method that inverts for the subsurface Q distribution by minimizing a skeletonized misfit function ∈, where ∈ is the sum of the squared differences between the observed and the predicted peak/centroid-frequency shifts of the early arrivals. The gradient is computed by migrating the observed traces weighted by the frequency shift residuals. The background Q model is perturbed until the predicted and the observed traces have the same peak frequencies or the same centroid frequencies. Numerical tests determined that an improved accuracy of the Q model by wave-equation Q tomography leads to a noticeable improvement in migration image quality. © 2016 Society of Exploration Geophysicists.

  11. Wave-equation Q tomography

    KAUST Repository

    Dutta, Gaurav; Schuster, Gerard T.

    2016-01-01

    Strong subsurface attenuation leads to distortion of amplitudes and phases of seismic waves propagating inside the earth. The amplitude and the dispersion losses from attenuation are often compensated for during prestack depth migration. However, most attenuation compensation or Qcompensation migration algorithms require an estimate of the background Q model. We have developed a wave-equation gradient optimization method that inverts for the subsurface Q distribution by minimizing a skeletonized misfit function ∈, where ∈ is the sum of the squared differences between the observed and the predicted peak/centroid-frequency shifts of the early arrivals. The gradient is computed by migrating the observed traces weighted by the frequency shift residuals. The background Q model is perturbed until the predicted and the observed traces have the same peak frequencies or the same centroid frequencies. Numerical tests determined that an improved accuracy of the Q model by wave-equation Q tomography leads to a noticeable improvement in migration image quality. © 2016 Society of Exploration Geophysicists.

  12. Coenzyme Q10 and Neurological Diseases

    Directory of Open Access Journals (Sweden)

    Gabriele Siciliano

    2009-12-01

    Full Text Available Coenzyme Q10 (CoQ10, or ubiquinone is a small electron carrier of the mitochondrial respiratory chain with antioxidant properties. CoQ10 supplementation has been widely used for mitochondrial disorders. The rationale for using CoQ10 is very powerful when this compound is primary decreased because of defective synthesis. Primary CoQ10 deficiency is a treatable condition, so heightened “clinical awareness” about this diagnosis is essential. CoQ10 and its analogue, idebenone, have also been widely used in the treatment of other neurodegenerative disorders. These compounds could potentially play a therapeutic role in Parkinson’s disease, Huntington’s disease, amyotrophic lateral sclerosis, Friedreich’s ataxia, and other conditions which have been linked to mitochondrial dysfunction. This article reviews the physiological roles of CoQ10, as well as the rationale and the role in clinical practice of CoQ10 supplementation in different neurological diseases, from primary CoQ10 deficiency to neurodegenerative disorders.

  13. Microstructure development and mechanical properties of quenching and partitioning (Q and P) steel and an incorporation of hot-dipping galvanization during Q and P process

    Energy Technology Data Exchange (ETDEWEB)

    Sun, Jing; Yu, Hao, E-mail: yhzhmr@126.com

    2013-12-01

    The “quenching and partitioning” (Q and P) process has recently been substantiated to be a unique technological route for the production of high strength steels with significant amounts of retained austenite, and thus to provide better combination of strength and ductility. In this work, intercritically annealed specimens followed by Q and P treatment have been applied to low-carbon steel with chemical composition typical for conventional TRIP-assisted steels. Microstructure of the steel treated by the Q and P process was characterized by means of optical microscope, SEM, TEM and XRD. The study suggests that microstructure is mainly composed of ferrite, lath martensite, martensite–austenite islands, retained austenite and a small amount of bainite formed during partitioning. The fraction of bainite formed during partitioning is proportional to quenching temperature. The mechanical property of specimen treated by the Q and P process exhibits an improved combination of strength and ductility than that of the Q and T process. Two schemes of hot-dipping galvanization processes were designed. The results indicate that both hot-dip galvanizing schemes present a limited reduction in tensile strength and a slight enhancement of ductility. The scheme of galvanizing and partitioning after the quenching progress shows a better combination of strength and ductility.

  14. Four novel Loci (19q13, 6q24, 12q24, and 5q14 influence the microcirculation in vivo.

    Directory of Open Access Journals (Sweden)

    M Kamran Ikram

    2010-10-01

    Full Text Available There is increasing evidence that the microcirculation plays an important role in the pathogenesis of cardiovascular diseases. Changes in retinal vascular caliber reflect early microvascular disease and predict incident cardiovascular events. We performed a genome-wide association study to identify genetic variants associated with retinal vascular caliber. We analyzed data from four population-based discovery cohorts with 15,358 unrelated Caucasian individuals, who are members of the Cohort for Heart and Aging Research in Genomic Epidemiology (CHARGE consortium, and replicated findings in four independent Caucasian cohorts (n  =  6,652. All participants had retinal photography and retinal arteriolar and venular caliber measured from computer software. In the discovery cohorts, 179 single nucleotide polymorphisms (SNP spread across five loci were significantly associated (p<5.0×10(-8 with retinal venular caliber, but none showed association with arteriolar caliber. Collectively, these five loci explain 1.0%-3.2% of the variation in retinal venular caliber. Four out of these five loci were confirmed in independent replication samples. In the combined analyses, the top SNPs at each locus were: rs2287921 (19q13; p  =  1.61×10(-25, within the RASIP1 locus, rs225717 (6q24; p = 1.25×10(-16, adjacent to the VTA1 and NMBR loci, rs10774625 (12q24; p  =  2.15×10(-13, in the region of ATXN2,SH2B3 and PTPN11 loci, and rs17421627 (5q14; p = 7.32×10(-16, adjacent to the MEF2C locus. In two independent samples, locus 12q24 was also associated with coronary heart disease and hypertension. Our population-based genome-wide association study demonstrates four novel loci associated with retinal venular caliber, an endophenotype of the microcirculation associated with clinical cardiovascular disease. These data provide further insights into the contribution and biological mechanisms of microcirculatory changes that underlie cardiovascular

  15. Jets at low Q2 at HERA and radiation damage studies for silicon sensors for the XFEL

    International Nuclear Information System (INIS)

    Perrey, Hanno

    2011-06-01

    In the first part this thesis, jet cross-sections were measured for inclusive jet, inclusive dijet, and inclusive trijet production at photon virtualities in the range of 10 2 2 . The data analyzed were recorded with the Zeus detector in the years 2004-2007 corresponding to an integrated luminosity of 296 pb -1 . Events in neutral current deep inelastic scattering were selected in the above stated Q 2 region for an inelasticity of 0.2 T,B >8 GeV and to have a pseudorapidity in the laboratory frame in the range of -1 lab jj >20 GeV to avoid phase space regions where the fixed order calculations are sensitive to infrared divergences. The presented analysis is the first jet analysis at such low values of Q 2 to exploit the full HERA-II ZEUS data set, and as such is performed at significant higher luminosities than previous publications. Overall, the next-to-leading order (NLO) calculations correctly predict the measured cross-sections within the uncertainties in all studied quantities and over most of the investigated regions of phase space, except in the pseudorapidity region close to the proton beam direction (''forward'' region) in inclusive jet production where the prediction is considerably below the data. The uncertainty of the NLO prediction, dominated by the uncertainty associated with the choice of the renormalization scale, is typically larger than the experimental uncertainty, which is for the most part dominated by the uncertainty of the jet energy scale. The large theoretical uncertainties indicate the need for calculations including higherorders. Such NNLO calculations will allow to fully exploit the sensitivity of the low Q 2 jet data in QCD PDF fits and in fits to extract values of α s . In the second part of this thesis, a study of radiation damage of silicon sensors by 12 keV X-rays for doses up to 1GGy is presented. For this study, an irradiation facility has been set up at Hasylab at Desy. Test structures (gate-controlled diodes) have been

  16. Partial trisomy 14q and monosomy 20q due to an unbalanced familial translocation

    Energy Technology Data Exchange (ETDEWEB)

    Menasse-Palmer, L; Leo, J.; Cannizaro, L. [Albert Einstein College of Medicine, Bronx, NY (United States)] [and others

    1994-09-01

    Partial trisomy of distal 14q and monosomy of 20q are rare. There have been several reports of a partial distal trisomy 14q with characteristic clinical findings, including hypogonadism and a conotruncal cardiac anomaly. There is no deletion distal 20q syndrome. We have recently examined a newborn with this unique duplication/deletion syndrome. Case report: J.S. was the 2980 gm product of a term uneventful pregnancy delivered to a 24-year-old gravida 2, para 1001 mother. The newborn exam revealed a dysmorphic newborn male with a sloping forehead, bitemporal narrowing, glabellar furrowing and micrognathia. A systolic murmur was audible. The genital abnormalities were micropenis, hypospadias with chordee and bifid scrotum with prominent raphe, and gonads were palpable. A CAT scan of the head revealed grade I IVH. An echocardiogram showed a VSD, ASD and an AP window. A sonogram of the liver showed absence of the gallbladder. Chromosome analysis revealed an abnormal male karyotype containing a derivative 20, subsequently shown to be inherited as a result of malsegregation of a paternal translocation: 46,XY,-20,+der(20)t(14;20)(q32.1;q13.3)pat. The infant fed poorly and required tube feedings and was treated for congestive heart failure with Digoxin, Lasix and oxygen. A decreased cortisol level and cholestasis were noted. The infant died after a cardiopulmonary arrest at one month of age. No post-mortem was obtained. Clinical cytogenetic correlation (conotruncal abnormality and hypogonadism) with partial duplication of distal 14q was positive. This case helps to further delineate duplication 14q and a syndrome due to partial deletion 20q.

  17. Comparison of low density and high density pedicle screw instrumentation in Lenke 1 adolescent idiopathic scoliosis.

    Science.gov (United States)

    Shen, Mingkui; Jiang, Honghui; Luo, Ming; Wang, Wengang; Li, Ning; Wang, Lulu; Xia, Lei

    2017-08-02

    The correlation between implant density and deformity correction has not yet led to a precise conclusion in adolescent idiopathic scoliosis (AIS). The aim of this study was to evaluate the effects of low density (LD) and high density (HD) pedicle screw instrumentation in terms of the clinical, radiological and Scoliosis Research Society (SRS)-22 outcomes in Lenke 1 AIS. We retrospectively reviewed 62 consecutive Lenke 1 AIS patients who underwent posterior spinal arthrodesis using all-pedicle screw instrumentation with a minimum follow-up of 24 months. The implant density was defined as the number of screws per spinal level fused. Patients were then divided into two groups according to the average implant density for the entire study. The LD group (n = 28) had fewer than 1.61 screws per level, while the HD group (n = 34) had more than 1.61 screws per level. The radiographs were analysed preoperatively, postoperatively and at final follow-up. The perioperative and SRS-22 outcomes were also assessed. Independent sample t tests were used between the two groups. Comparisons between the two groups showed no significant differences in the correction of the main thoracic curve and thoracic kyphosis, blood transfusion, hospital stay, and SRS-22 scores. Compared with the HD group, there was a decreased operating time (278.4 vs. 331.0 min, p = 0.004) and decreased blood loss (823.6 vs. 1010.9 ml, p = 0.048), pedicle screws needed (15.1 vs. 19.6, p density and high density pedicle screw instrumentation achieved satisfactory deformity correction in Lenke 1 AIS patients. However, the operating time and blood loss were reduced, and the implant costs were decreased with the use of low screw density constructs.

  18. I-Love-Q to the extreme

    Science.gov (United States)

    Silva, Hector O.; Yunes, Nicolás

    2018-01-01

    Certain bulk properties of neutron stars, in particular their moment of inertia, rotational quadrupole moment and tidal Love number, when properly normalized, are related to one another in a nearly equation of state independent way. The goal of this paper is to test these relations with extreme equations of state at supranuclear densities constrained to satisfy only a handful of generic, physically sensible conditions. By requiring that the equation of state be (i) barotropic and (ii) its associated speed of sound be real, we construct a piecewise function that matches a tabulated equation of state at low densities, while matching a stiff equation of state parametrized by its sound speed in the high-density region. We show that the I-Love-Q relations hold to 1 percent with this class of equations of state, even in the extreme case where the speed of sound becomes superluminal and independently of the transition density. We also find further support for the interpretation of the I-Love-Q relations as an emergent symmetry due to the nearly constant eccentricity of isodensity contours inside the star. These results reinforce the robustness of the I-Love-Q relations against our current incomplete picture of physics at supranuclear densities, while strengthening our confidence in the applicability of these relations in neutron star astrophysics.

  19. Measurement of target and double-spin asymmetries for the e ⃗p ⃗→e π+(n ) reaction in the nucleon resonance region at low Q2

    Science.gov (United States)

    Zheng, X.; Adhikari, K. P.; Bosted, P.; Deur, A.; Drozdov, V.; El Fassi, L.; Kang, Hyekoo; Kovacs, K.; Kuhn, S.; Long, E.; Phillips, S. K.; Ripani, M.; Slifer, K.; Smith, L. C.; Adikaram, D.; Akbar, Z.; Amaryan, M. J.; Anefalos Pereira, S.; Asryan, G.; Avakian, H.; Badui, R. A.; Ball, J.; Baltzell, N. A.; Battaglieri, M.; Batourine, V.; Bedlinskiy, I.; Biselli, A. S.; Briscoe, W. J.; Bültmann, S.; Burkert, V. D.; Carman, D. S.; Celentano, A.; Chandavar, S.; Charles, G.; Chen, J.-P.; Chetry, T.; Choi, Seonho; Ciullo, G.; Clark, L.; Colaneri, L.; Cole, P. L.; Compton, N.; Contalbrigo, M.; Crede, V.; D'Angelo, A.; Dashyan, N.; De Vita, R.; De Sanctis, E.; Djalali, C.; Dodge, G. E.; Dupre, R.; Egiyan, H.; El Alaoui, A.; Elouadrhiri, L.; Eugenio, P.; Fanchini, E.; Fedotov, G.; Fersch, R.; Filippi, A.; Fleming, J. A.; Gevorgyan, N.; Ghandilyan, Y.; Gilfoyle, G. P.; Giovanetti, K. L.; Girod, F. X.; Gleason, C.; Golovach, E.; Gothe, R. W.; Griffioen, K. A.; Guidal, M.; Guler, N.; Guo, L.; Hanretty, C.; Harrison, N.; Hattawy, M.; Hicks, K.; Holtrop, M.; Hughes, S. M.; Ilieva, Y.; Ireland, D. G.; Ishkhanov, B. S.; Isupov, E. L.; Jenkins, D.; Jiang, H.; Jo, H. S.; Joosten, S.; Keller, D.; Khachatryan, G.; Khandaker, M.; Kim, A.; Kim, W.; Klein, F. J.; Kubarovsky, V.; Lanza, L.; Lenisa, P.; Livingston, K.; MacGregor, I. J. D.; Markov, N.; McKinnon, B.; Mirazita, M.; Mokeev, V.; Movsisyan, A.; Munevar, E.; Munoz Camacho, C.; Murdoch, G.; Nadel-Turonski, P.; Net, L. A.; Ni, A.; Niccolai, S.; Niculescu, G.; Niculescu, I.; Osipenko, M.; Ostrovidov, A. I.; Paolone, M.; Paremuzyan, R.; Park, K.; Pasyuk, E.; Peng, P.; Pisano, S.; Pogorelko, O.; Price, J. W.; Puckett, A. J. R.; Raue, B. A.; Rizzo, A.; Rosner, G.; Rossi, P.; Roy, P.; Sabatié, F.; Salgado, C.; Schumacher, R. A.; Sharabian, Y. G.; Skorodumina, Iu.; Smith, G. D.; Sokhan, D.; Sparveris, N.; Stankovic, I.; Strakovsky, I. I.; Strauch, S.; Taiuti, M.; Tian, Ye; Ungaro, M.; Voskanyan, H.; Voutier, E.; Walford, N. K.; Watts, D. P.; Wei, X.; Weinstein, L. B.; Wood, M. H.; Zachariou, N.; Zhang, J.; Zonta, I.; CLAS Collaboration

    2016-10-01

    We report measurements of target- and double-spin asymmetries for the exclusive channel e ⃗p ⃗→e π+(n ) in the nucleon resonance region at Jefferson Lab using the CEBAF Large Acceptance Spectrometer (CLAS). These asymmetries were extracted from data obtained using a longitudinally polarized NH3 target and a longitudinally polarized electron beam with energies 1.1, 1.3, 2.0, 2.3, and 3.0 GeV. The new results are consistent with previous CLAS publications but are extended to a low Q2 range from 0.0065 to 0.35 (GeV/c ) 2 . The Q2 access was made possible by a custom-built Cherenkov detector that allowed the detection of electrons for scattering angles as low as 6∘. These results are compared with the unitary isobar models JANR and MAID, the partial-wave analysis prediction from SAID, and the dynamic model DMT. In many kinematic regions our results, in particular results on the target asymmetry, help to constrain the polarization-dependent components of these models.

  20. Coenzyme Q10 defects may be associated with a deficiency of Q10-independent mitochondrial respiratory chain complexes

    Directory of Open Access Journals (Sweden)

    Konstantina Fragaki

    Full Text Available BACKGROUND: Coenzyme Q10 (CoQ10 or ubiquinone deficiency can be due either to mutations in genes involved in CoQ10 biosynthesis pathway, or to mutations in genes unrelated to CoQ10 biosynthesis. CoQ10 defect is the only oxidative phosphorylation disorder that can be clinically improved after oral CoQ10 supplementation. Thus, early diagnosis, first evoked by mitochondrial respiratory chain (MRC spectrophotometric analysis, then confirmed by direct measurement of CoQ10 levels, is of critical importance to prevent irreversible damage in organs such as the kidney and the central nervous system. It is widely reported that CoQ10 deficient patients present decreased quinone-dependent activities (segments I + III or G3P + III and II + III while MRC activities of complexes I, II, III, IV and V are normal. We previously suggested that CoQ10 defect may be associated with a deficiency of CoQ10-independent MRC complexes. The aim of this study was to verify this hypothesis in order to improve the diagnosis of this disease. RESULTS: To determine whether CoQ10 defect could be associated with MRC deficiency, we quantified CoQ10 by LC-MSMS in a cohort of 18 patients presenting CoQ10-dependent deficiency associated with MRC defect. We found decreased levels of CoQ10 in eight patients out of 18 (45 %, thus confirming CoQ10 disease. CONCLUSIONS: Our study shows that CoQ10 defect can be associated with MRC deficiency. This could be of major importance in clinical practice for the diagnosis of a disease that can be improved by CoQ10 supplementation.

  1. Measurement of the neutron (3He) spin structure functions at low Q2: A connection between the Bjorken and gerasimov-drell-hearn sum rule

    Energy Technology Data Exchange (ETDEWEB)

    Djawotho, Pibero [College of William and Mary, Williamsburg, VA (United States)

    2002-12-01

    This dissertation presents results of experiment E94-010 performed at Jefferson Laboratory (simply known as JLab) in Hall A. The experiment aimed to measure the low Q2 evolution of the Gerasimov-Drell-Hearn (GDH) integral from Q2 = 0.1 to 0.9 GeV2. The GDH sum rule at the real photon point provides an important test of Quantum Chromodynamics (QCD). The low Q2 evolution of the GDH integral contests various resonance models, Chiral Perturbation Theory ({chi} PT) and lattice QCD calculations, but more importantly, it helps us understand the transition between partonic and hadronic degrees of freedom. At high Q2, beyond 1 GeV2, the difference of the GDH integrals for the proton and the neutron is related to the Bjorken sum rule, another fundamental test of QCD. In addition, results of the measurements for the spin structure functions g1 and g2, cross sections, and asymmetries are presented. E94-010 was the first experiment of its kind at JLab. It used a high-pressure, polarized 3He target with a gas pressure of 10 atm and average target polarization of 35%. For the first time, the polarized electron source delivered an average beam polarization of 70% with a beam current of 15 micro A. The limit on the beam current was only imposed by the target. The experiment required six different beam energies from 0.86 to 5.1 GeV. This was the first time the accelerator ever reached 5.1 GeV. Both High-Resolution Spectrometers of Hall A, used in singles mode, were positioned at 15.5 ° each.

  2. Coenzyme Q10 production in plants: current status and future prospects.

    Science.gov (United States)

    Parmar, Sanjay Singh; Jaiwal, Anjali; Dhankher, Om Parkash; Jaiwal, Pawan K

    2015-06-01

    Coenzyme Q10 (CoQ10) or Ubiquinone10 (UQ10), an isoprenylated benzoquinone, is well-known for its role as an electron carrier in aerobic respiration. It is a sole representative of lipid soluble antioxidant that is synthesized in our body. In recent years, it has been found to be associated with a range of patho-physiological conditions and its oral administration has also reported to be of therapeutic value in a wide spectrum of chronic diseases. Additionally, as an antioxidant, it has been widely used as an ingredient in dietary supplements, neutraceuticals, and functional foods as well as in anti-aging creams. Since its limited dietary uptake and decrease in its endogenous synthesis in the body with age and under various diseases states warrants its adequate supply from an external source. To meet its growing demand for pharmaceutical, cosmetic and food industries, there is a great interest in the commercial production of CoQ10. Various synthetic and fermentation of microbial natural producers and their mutated strains have been developed for its commercial production. Although, microbial production is the major industrial source of CoQ10 but due to low yield and high production cost, other cost-effective and alternative sources need to be explored. Plants, being photosynthetic, producing high biomass and the engineering of pathways for producing CoQ10 directly in food crops will eliminate the additional step for purification and thus could be used as an ideal and cost-effective alternative to chemical synthesis and microbial production of CoQ10. A better understanding of CoQ10 biosynthetic enzymes and their regulation in model systems like E. coli and yeast has led to the use of metabolic engineering to enhance CoQ10 production not only in microbes but also in plants. The plant-based CoQ10 production has emerged as a cost-effective and environment-friendly approach capable of supplying CoQ10 in ample amounts. The current strategies, progress and constraints of

  3. RecQ Helicases

    DEFF Research Database (Denmark)

    Larsen, Nicolai Balle; Hickson, Ian D

    2013-01-01

    The RecQ family of DNA helicases is highly conserved throughout -evolution, and is important for the maintenance of genome stability. In humans, five RecQ family members have been identified: BLM, WRN, RECQ4, RECQ1 and RECQ5. Defects in three of these give rise to Bloom's syndrome (BLM), Werner...

  4. Two-Stage Design Method for Enhanced Inductive Energy Transmission with Q-Constrained Planar Square Loops.

    Directory of Open Access Journals (Sweden)

    Akaa Agbaeze Eteng

    Full Text Available Q-factor constraints are usually imposed on conductor loops employed as proximity range High Frequency Radio Frequency Identification (HF-RFID reader antennas to ensure adequate data bandwidth. However, pairing such low Q-factor loops in inductive energy transmission links restricts the link transmission performance. The contribution of this paper is to assess the improvement that is reached with a two-stage design method, concerning the transmission performance of a planar square loop relative to an initial design, without compromise to a Q-factor constraint. The first stage of the synthesis flow is analytical in approach, and determines the number and spacing of turns by which coupling between similar paired square loops can be enhanced with low deviation from the Q-factor limit presented by an initial design. The second stage applies full-wave electromagnetic simulations to determine more appropriate turn spacing and widths to match the Q-factor constraint, and achieve improved coupling relative to the initial design. Evaluating the design method in a test scenario yielded a more than 5% increase in link transmission efficiency, as well as an improvement in the link fractional bandwidth by more than 3%, without violating the loop Q-factor limit. These transmission performance enhancements are indicative of a potential for modifying proximity HF-RFID reader antennas for efficient inductive energy transfer and data telemetry links.

  5. A Case of 17q21.31 Microduplication and 7q31.33 Microdeletion, Associated with Developmental Delay, Microcephaly, and Mild Dysmorphic Features

    Directory of Open Access Journals (Sweden)

    Adrian Mc Cormack

    2014-01-01

    Full Text Available Concurrent cryptic microdeletion and microduplication syndromes have recently started to reveal themselves with the advent of microarray technology. Analysis has shown that low-copy repeats (LCRs have allowed chromosome regions throughout the genome to become hotspots for nonallelic homologous recombination to take place. Here, we report a case of a 7.5-year-old girl who manifests microcephaly, developmental delay, and mild dysmorphic features. Microarray analysis identified a microduplication in chromosome 17q21.31, which encompasses the CRHR1, MAPT, and KANSL1 genes, as well as a microdeletion in chromosome 7q31.33 that is localised within the GRM8 gene. To our knowledge this is one of only a few cases of 17q21.31 microduplication. The clinical phenotype of patients with this microduplication is milder than of those carrying the reciprocal microdeletions, and suggests that the lower incidence of the former compared to the latter may be due to underascertainment.

  6. High-Q plasmonic bottle microresonator

    Science.gov (United States)

    Mohd Nasir, M. Narizee; Ding, Ming; Murugan, G. Senthil; Zervas, Michalis N.

    2014-03-01

    In this paper, we demonstrate a hybrid plasmonic bottle microresonator (PBMR) which supports whispering gallery modes (WGMs) along with surface plasmon waves (SPWs) for high performance optical sensor applications. The BMR was fabricated through "soften-and-compress" technique with a thin gold layer deposited on top of the resonator. A polarization-resolved measurement was set-up in order to fully characterize the fabricated PBMR. Initially, the uncoated BMR with waist diameter of 181 μm, stem diameter of 125 μm and length of 400 μm was fabricated and then gold film was deposited on the surface. Due to surface curvature, the gold film covering half of the BMR had a characteristic meniscus shape and maximum thickness of 30 nm. The meniscus provides appropriately tapered edges which facilitate the adiabatic transformation of BMR WGMs to SPWs and vice versa. This results in low transition losses, which combined with partially-metal-coated resonator, can result in high hybrid-PBMR Q's. The transmission spectra of the hybrid PBMR are dramatically different to the original uncoated BMR. Under TE(TM) excitation, the PBMR showed composite resonances with Q of ~2100(850) and almost identical ~ 3 nm FSR. We have accurately fitted the observed transmission resonances with Lorentzian-shaped curves and showed that the TE and TM excitations are actually composite resonances comprise of two and three partially overlapping resonances with Q's in excess of 2900 and 2500, respectively. To the best of our knowledge these are the highest Qs observed in plasmonic microcavities.

  7. Q-values and Attenuation of the Shallow Crust Under Uturuncu Volcano, Bolivia

    Science.gov (United States)

    Mcfarlin, H. L.; McNutt, S. R.; Thompson, G.

    2017-12-01

    Uturuncu Volcano, located in the Altiplano-Puna region of the central Andes, near the border of Bolivia and Chile, has been shown to be inflating at a rate of 1-2 cm/yr over an area that is about 70 km wide. The PLUTONS project deployed 28 broadband seismometers around Uturuncu from April 2009 to October 2012. Several thousand shallow (depth < 20 km) local earthquakes were recorded. Attenuation of seismic waves along travel paths for these local crustal earthquakes can be measured by calculating Q-values, which we have performed using the method of single station spectral ratios by Frankel (1982). Large scatter in the Q-values for various distances and travel times appear to be a function of variations in source depth, focal mechanism, and back azimuth. Preliminary Q-values were calculated for azimuths in 30° increments in sectors around each station. Estimates for Q range from about 60 to 700, with many showing a low Q in the direction of the summit from each station. This suggests that the volcanic pile is more highly attenuating than the surrounding crust.

  8. Olanzapine induced Q-Tc shortening.

    Science.gov (United States)

    Shoja Shafti, Saeed; Fallah Jahromi, Parisa

    2014-12-01

    Prolongation of Q-Tc interval is commonly accepted as a surrogate marker for the ability of a drug to cause torsade de pointes. In the present study, safety of olanzapine versus risperidone was compared among a group of patients with schizophrenia to see the frequency of the electrocardiographic alterations induced by those atypical antipsychotics. Two hundred and sixty-eight female inpatients with schizophrenia entered in one of the two parallel groups to participate in an open study for random assignment to olanzapine (n = 148) or risperidone (n = 120). Standard 12-lead surface electrocardiogram (ECG) was taken from each patient at baseline, before initiation of treatment, and then at the end of management, just before discharge. The parameters that were assessed included heart rate (HR), P-R interval, QRS interval, Q-T interval (corrected = Q-Tc), ventricular activation time (VAT), ST segment, T wave, axis of QRS, and finally, interventricular conduction process. A total of 37.83% of cases in the olanzapine group and 30% in the risperidone group showed some Q-Tc changes; 13.51% and 24.32% of the patients in the olanzapine group showed prolongation and shortening of the Q-Tc, respectively, while changes in the risperidone group were restricted to only prolongation of Q-Tc. Comparison of means showed a significant increment in Q-Tc by risperidone (p = 0.02). Also, comparison of proportions in the olanzapine group showed significantly more cases with shortening of Q-Tc versus its prolongation (p = 0.01). No significant alterations with respect to other variables were evident. Olanzapine and risperidone had comparable potentiality for induction of Q-Tc changes, while production of further miscellaneous alterations in ECG was more observable in the olanzapine group compared with the risperidone group. Also shortening of Q-Tc was specific to olanzapine.

  9. Analysis on detection accuracy of binocular photoelectric instrument optical axis parallelism digital calibration instrument

    Science.gov (United States)

    Ying, Jia-ju; Yin, Jian-ling; Wu, Dong-sheng; Liu, Jie; Chen, Yu-dan

    2017-11-01

    Low-light level night vision device and thermal infrared imaging binocular photoelectric instrument are used widely. The maladjustment of binocular instrument ocular axises parallelism will cause the observer the symptom such as dizziness, nausea, when use for a long time. Binocular photoelectric equipment digital calibration instrument is developed for detecting ocular axises parallelism. And the quantitative value of optical axis deviation can be quantitatively measured. As a testing instrument, the precision must be much higher than the standard of test instrument. Analyzes the factors that influence the accuracy of detection. Factors exist in each testing process link which affect the precision of the detecting instrument. They can be divided into two categories, one category is factors which directly affect the position of reticle image, the other category is factors which affect the calculation the center of reticle image. And the Synthesize error is calculated out. And further distribute the errors reasonably to ensure the accuracy of calibration instruments.

  10. On q-analogues of the Mangontarum transform for certain q-Bessel functions and some application

    Directory of Open Access Journals (Sweden)

    S.K.Q. Al-Omari

    2016-10-01

    Full Text Available Several q-analogues of certain integral transforms have been recently investigated by many authors in the recent past. In this paper, we introduce certain analogues of the so-called q-Mangontarum transform and implement the proposed variants to given classes of q-Bessel functions. The results of this paper are new and complement the previously known results of Mangontarum (2014. Some results related to q-Laplace transforms are also obtained.

  11. Q-deformed systems and constrained dynamics

    International Nuclear Information System (INIS)

    Shabanov, S.V.

    1993-01-01

    It is shown that quantum theories of the q-deformed harmonic oscillator and one-dimensional free q-particle (a free particle on the 'quantum' line) can be obtained by the canonical quantization of classical Hamiltonian systems with commutative phase-space variables and a non-trivial symplectic structure. In the framework of this approach, classical dynamics of a particle on the q-line coincides with the one of a free particle with friction. It is argued that q-deformed systems can be treated as ordinary mechanical systems with the second-class constraints. In particular, second-class constrained systems corresponding to the q-oscillator and q-particle are given. A possibility of formulating q-deformed systems via gauge theories (first-class constrained systems) is briefly discussed. (orig.)

  12. Quasi quantum group covariant q-oscillators

    International Nuclear Information System (INIS)

    Schomerus, V.

    1992-05-01

    If q is a p-th root of unity there exists a quasi-co-associative truncated quantum group algebra U T q (sl 2 ) whose indecomposable representations are the physical representations of U q (sl 2 ), whose co-product yields the truneated tensor product of physical representations of U q (sl 2 ), and whose R-matrix satisfies quasi Yang Baxter equations. For primitive p-th roots q, we consider a 2-dimensional q-oscillator which admits U T q (sl 2 ) as a symmetry algebra. Its wave functions lie in a space F T q of 'functions on the truncated quantum plane', i.e. of polynomials in noncommuting complex coordinate functions z a , on which multiplication operators Z a and the elements of U T q (sl 2 ) can act. This illustrates the concept of quasi quantum planes. Due to the truncation, the Hilbert space of states is finite dimensional. The subspaces F T(n) of monomials in x a of n-th degree vanish for n ≥ p-1, and F T(n) carries the 2J+1 dimensional irreducible representation of U T q (sl 2 ) if n=2J, J=0, 1/2, ... 1/2(p-2). Partial derivatives δ a are introduced. We find a *-operation on the algebra of multiplication operators Z i and derivatives δ b such that the adjoints Z * a act as differentiation on the truncated quantum plane. Multiplication operators Z a ('creation operators') and their adjoints ('annihilation operators') obey q -1/2 -commutation relations. The *-operation is used to determine a positive definite scalar product on the truncated quantum plane F T q . Some natural candidates of Hamiltonians for the q-oscillators are determined. (orig./HSI)

  13. Colorectal cancer linkage on chromosomes 4q21, 8q13, 12q24, and 15q22.

    Directory of Open Access Journals (Sweden)

    Mine S Cicek

    Full Text Available A substantial proportion of familial colorectal cancer (CRC is not a consequence of known susceptibility loci, such as mismatch repair (MMR genes, supporting the existence of additional loci. To identify novel CRC loci, we conducted a genome-wide linkage scan in 356 white families with no evidence of defective MMR (i.e., no loss of tumor expression of MMR proteins, no microsatellite instability (MSI-high tumors, or no evidence of linkage to MMR genes. Families were ascertained via the Colon Cancer Family Registry multi-site NCI-supported consortium (Colon CFR, the City of Hope Comprehensive Cancer Center, and Memorial University of Newfoundland. A total of 1,612 individuals (average 5.0 per family including 2.2 affected were genotyped using genome-wide single nucleotide polymorphism linkage arrays; parametric and non-parametric linkage analysis used MERLIN in a priori-defined family groups. Five lod scores greater than 3.0 were observed assuming heterogeneity. The greatest were among families with mean age of diagnosis less than 50 years at 4q21.1 (dominant HLOD = 4.51, α = 0.84, 145.40 cM, rs10518142 and among all families at 12q24.32 (dominant HLOD = 3.60, α = 0.48, 285.15 cM, rs952093. Among families with four or more affected individuals and among clinic-based families, a common peak was observed at 15q22.31 (101.40 cM, rs1477798; dominant HLOD = 3.07, α = 0.29; dominant HLOD = 3.03, α = 0.32, respectively. Analysis of families with only two affected individuals yielded a peak at 8q13.2 (recessive HLOD = 3.02, α = 0.51, 132.52 cM, rs1319036. These previously unreported linkage peaks demonstrate the continued utility of family-based data in complex traits and suggest that new CRC risk alleles remain to be elucidated.

  14. Constitutional 11q14-q22 chromosome deletion syndrome in a child with neuroblastoma MYCN single copy.

    Science.gov (United States)

    Passariello, Annalisa; De Brasi, Daniele; Defferrari, Raffaella; Genesio, Rita; Tufano, Maria; Mazzocco, Katia; Capasso, Maria; Migliorati, Roberta; Martinsson, Tommy; Siani, Paolo; Nitsch, Lucio; Tonini, Gian Paolo

    2013-11-01

    Constitutional 11q deletion is a chromosome imbalance possibly found in MCA/MR patients analyzed for chromosomal anomalies. Its role in determining the phenotype depends on extension and position of deleted region. Loss of heterozygosity of 11q (region 11q23) is also associated with neuroblastoma, the most frequent extra cranial cancer in children. It represents one of the most frequent cytogenetic abnormalities observed in the tumor of patients with high-risk disease even if germline deletion of 11q in neuroblastoma is rare. Hereby, we describe a 18 months old girl presenting with trigonocephaly and dysmorphic facial features, including hypotelorism, broad depressed nasal bridge, micrognathia, synophrys, epicanthal folds, and with a stage 4 neuroblastoma without MYCN amplification, carrying a germline 11q deletion (11q14.1-q22.3), outside from Jacobsen syndrome and from neuroblastoma 11q critical regions. The role of 11q deletion in determining the clinical phenotype and its association with neuroblastoma development in the patient are discussed. Copyright © 2013 Elsevier Masson SAS. All rights reserved.

  15. Cold-Induced Ascites in Broilers: Effects of Vitamin C and Coenzyme Q10

    Directory of Open Access Journals (Sweden)

    MH Nemati

    Full Text Available ABSTRACT We hypothesized that the supplementation of vitamin C (Vit. C and coenzyme Q10 (CoQ10 alone or in combination could reduce the negative effects of cold stress in broilers. Four hundred male chicks were exposed for 24 h to cold stress (15 ºC starting from 15d of age, while a positive control group (PC, 100 birds was kept under normal temperature condition. The experimental groups under cold stress (four treatments in 5 replicates of 20 birds were: negative control (NC, basal diet, Vit. C (basal diet + 300 mg/kg Vit. C, CoQ10 (basal diet + 40 mg/kg CoQ10 and Vit. C plus CoQ10 (basal diet + Vit. C+ CoQ10at above mentioned doses. Vit. C or CoQ10 supplementation were restored (p<0.01 performance and lowered (p<0.01 ascites mortality. Blood hematocrit and hemoglobin concentration were decreased (p<0.01 to the level comparable to PC by Vit. C supplementation. Lower plasma concentrations of thyroxin (T4 and higher triiodothyronine (T3 were observed in NC birds (p<0.01 and were not affected by Vit. C or CoQ10. In conclusion, supplementation of Vit. C or CoQ10 in diet of broilers under cold stress conditions resulted improved performance parameters (body weight and feed conversion ratio and ascites related traits (low red blood cell count, hematocrit, T3, and heart weights and high T4. No additional benefit was observed by combination of Vit. C and CoQ10.

  16. 7Q10 flows for SRS streams

    International Nuclear Information System (INIS)

    Chen, K.F.

    1996-01-01

    The Environmental Transport Group of the Environmental Technology Section was requested to predict the seven-day ten-year low flow (7Q10 flow) for the SRS streams based on historical stream flow records. Most of the historical flow records for the SRS streams include reactor coolant water discharged from the reactors and process water released from the process facilities. The most straight forward way to estimate the stream daily natural flow is to subtract the measured upstream reactor and/or facility daily effluents from the measured downstream daily flow. Unfortunately, this method does not always work, as indicated by the fact that sometimes the measured downstream volumetric flow rates are lower than the reactor effluent volumetric flow rates. For those cases that cannot be analyzed with the simple subtracting method, an alternative method was used to estimate the stream natural flows by statistically separating reactor coolant and process water flow data. The correlation between the calculated 7Q10 flows and the watershed areas for Four Mile Branch and Pen Branch agrees with that calculated by the USGS for Upper Three Runs and Lower Three Runs Creeks. The agreement between these two independent calculations lends confidence to the 7Q10 flow calculations presented in this report

  17. q-bosons, Toda lattice, Pieri rules and Baxter q-operator

    International Nuclear Information System (INIS)

    Duval, Antoine; Pasquier, Vincent

    2016-01-01

    We use the Pieri rules to recover the q-boson model and show it is equivalent to a discretized version of the relativistic Toda chain. We identify its semi infinite transfer matrix and the corresponding Baxter Q-matrix with half vertex operators related by an ω-duality transformation. We observe that the scalar product of two higher spin XXZ wave functions can be expressed with a Gaudin determinant. (paper)

  18. Instrumentation status of the low-b magnet systems at the Large Hadron Collider (LHC)

    CERN Document Server

    Darve, C.; Casas-Cubillos, J.; Perin, A.; Vauthier, N.

    2011-01-01

    The low-beta magnet systems are located in the Large Hadron Collider (LHC) insertion regions around the four interaction points. They are the key elements in the beams focusing/defocusing process allowing proton collisions at luminosity up to 10**34/cm**2s. Those systems are a contribution of the US-LHC Accelerator project. The systems are mainly composed of the quadrupole magnets (triplets), the separation dipoles and their respective electrical feed-boxes (DFBX). The low-beta magnet systems operate in an environment of extreme radiation, high gradient magnetic field and high heat load to the cryogenic system due to the beam dynamic effect. Due to the severe environment, the robustness of the diagnostics is primordial for the operation of the triplets. The hardware commissioning phase of the LHC was completed in February 2010. In the sake of a safer and more user-friendly operation, several consolidations and instrumentation modifications were implemented during this commissioning phase. This paper presents ...

  19. Instrumentation Status of the Low-β Magnet Systems at the Large Hadron Collider (LHC)

    CERN Document Server

    Darve, C; Casas-Cubillos, J; Perin, A; Vauthier, N

    2011-01-01

    The low-β magnet systems are located in the Large Hadron Collider (LHC) insertion regions around the four interaction points. They are the key elements in the beams focusing/defocusing process allowing proton collisions at luminosity up to 1034cm-2s-1. Those systems are a contribution of the US-LHC Accelerator project. The systems are mainly composed of the quadrupole magnets (triplets), the separation dipoles and their respective electrical feed-boxes (DFBX). The low-β magnet systems operate in an environment of extreme radiation, high gradient magnetic field and high heat load to the cryogenic system due to the beam dynamic effect. Due to the severe environment, the robustness of the diagnostics is primordial for the operation of the triplets. The hardware commissioning phase of the LHC was completed in February 2010. In the sake of a safer and more user-friendly operation, several consolidations and instrumentation modifications were implemented during this commissioning phase. This paper presents the in...

  20. Comparative genomic hybridization analysis detects frequent over-representation of DNA sequences at 3q, 7p, 8q and 18q in head and neck carcinomas

    DEFF Research Database (Denmark)

    Bergamo, N A; Rogatto, S R; Poli-Frederico, R C

    2000-01-01

    Comparative genomic hybridization (CGH) was used to identify chromosomal imbalances in 19 samples of squamous cell carcinoma of the head and neck (HNSCC). The chromosome arms most often over-represented were 3q (48%), 8q (42%), and 7p (32%); in many cases, these changes were observed at high copy...... and 2q material were detected in patients exhibiting a clinical history of recurrence and/or metastasis followed by terminal disease. This association suggests that gain of 1q and 2q may be a new marker of head and neck tumors with a refractory clinical response....

  1. 1999 ESH&Q Liability Assessment Report of Envirocare of Utah, Inc. Clive, Utah

    Energy Technology Data Exchange (ETDEWEB)

    Trump, D. E. [INEEL; Vilord, C. E.

    1999-07-01

    This report contains the results of an environment, safety, health, and quality (ESH&Q) assessment of the treatment technologies and treatment-related operations that was conducted of Envirocare of Utah, Inc. (EOU). EOU is a lowlevel radioactive and mixed Resource Conservation and Recovery Act (RCRA)- regulated haz.ardous low-level radioactive waste (mixed low-level waste) treatment/disposal facility located near Clive, Utah. An ESH&Q assessment of the EOU Clive, Utah facility treatment technologies and related treatment operations was conducted in mid-April 1999. The assessment was required as part of the technical evaluation of proposals received by Lockheed Martin Idaho Technologies Company (LMITCO) for modification of a mixed low-level radioactive waste disposal subcontract (No.K79-180572). The EOU Clive, Utah facility is proposed as a potential treatment/disposal facility for mixed low-level radioactive waste regulated under the RCRA and the Atomic Energy Act

  2. Some aspects of q-boson calculus

    International Nuclear Information System (INIS)

    Smirnov, Yu.F.; Kibler, M.R.

    1992-10-01

    The Jordan-Schwinger calculus is discussed, using deformed bosons. This work constitutes a first step toward a complete study of the SU q (2) unit tensor. The objective is to find a realization of the components of this tensor in terms of q-bosons. The q-deformed Schwinger algebra relative to SU q (2) is defined, and an algorithm for producing recurrent relations between Clebsch-Gordan coefficients for SU q (2) is given. (K.A.) 18 refs

  3. Partial trisomy 5q resulting from chromosome 7 insertion: An expansion of the phenotype

    Energy Technology Data Exchange (ETDEWEB)

    Fries, M.H.; Reilly, P.A.; Williams, T.C. [Keesler Medical Center, MS (United States)] [and others

    1994-09-01

    Partial trisomy 5q has been categorized into three separate phenotypes; however, a distinctive phenotype has not been described for duplications spanning 5q23-q35. We report a case of partial trisomy 5q for this region as a result of a ins(7,5)(q31.3;q23.2q35.1)mat. The liveborn male infant was delivered by emergency cesarean section at 37 weeks after a pregnancy notable for oligohydramnios, with birth weight 1792 g (<3%). Postnatal course was marked by psychomotor delay, failure to thrive, and biopsy demonstrated neonatal giant cell hepatitis with a paucity of intrahepatic bile ducts. His appearance was remarkable for lack of subcutaneous fat, midline displaced hair whorl, bitemporal narrowing with frontal bossing, wide anterior fontanel, widow`s peak, protuberant eyes with periorbital and lid edema, short flat nasal bridge with broad flattened nasal tip, long smooth philtrum, wide mouth with thin lips, wide gingival ridges, micrognathia, posteriorly rotated low-set ears, hepatomegaly, flexion contractions of elbows, and generalized hypertonicity. Urine organic acids, oligosaccharide/mucopolysaccharide screen, and plasma amino acids were negative. GTG-banding on prometaphase chromosomes showed an unbalanced translocation involving chr. 7. This was identified as an insertion of chr. 5 (q23.2q35.1) into distal 7q after FISH using chr. 5 and chr. 7 painting probes. The infant`s mother carries the balanced insertional rearrangement: 46,XX,dir ins(7,5)(q31.3;q23.2q35.1). This phenotype overlaps that of previously described duplications with the addition of giant cell hepatitis, coarsened facial features, gingival thickening, and flexion contractures, suggestive of a yet undiagnosed storage disorder.

  4. Measurement of nurses' attitudes and knowledge regarding acute care older patients: Psychometrics of the OPACS-US combined with the KOP-Q.

    Science.gov (United States)

    Dikken, Jeroen; Hoogerduijn, Jita G; Lagerwey, Mary D; Shortridge-Baggett, Lillie; Klaassen, Sharon; Schuurmans, Marieke J

    In clinical practice, identifying positive and negative attitudes toward older patients is very important to improve quality of care provided to them. The Older People in Acute Care Survey - United States (OPACS-US) is an instrument measuring hospital nurses attitudes regarding older patients. However, psychometrics have never been assessed. Furthermore, knowledge being related to attitude and behavior should also be measured complementing the OPACS-US. The purpose of this study was to assess structural validity and reliability of the OPACS-US and assess whether the OPACS-US can be complemented with the Knowledge about Older Patients-Quiz (KOP-Q). A multicenter cross sectional design was conducted. Registered nurses (n = 130, mean age 39,9 years; working experience 14,6 years) working in four general hospitals were included in the study. Nurses completed the OPACS-US section A: practice experiences, B: general opinion and the KOP-Q online. Findings demonstrated that the OPACS-US is a valid and reliable survey instrument that measures practice experiences and general opinion. Furthermore, the OPACS-US can be combined with the KOP-Q adding a knowledge construct, and is ready for use within education and/or quality improvement programs in the USA. Copyright © 2017 Elsevier Inc. All rights reserved.

  5. Measurement of the generalized polarizabilities of the proton in virtual Compton scattering at Q2=0.92 and 1.76 GeV2.

    Science.gov (United States)

    Laveissière, G; Todor, L; Degrande, N; Jaminion, S; Jutier, C; Di Salvo, R; Van Hoorebeke, L; Alexa, L C; Anderson, B D; Aniol, K A; Arundell, K; Audit, G; Auerbach, L; Baker, F T; Baylac, M; Berthot, J; Bertin, P Y; Bertozzi, W; Bimbot, L; Boeglin, W U; Brash, E J; Breton, V; Breuer, H; Burtin, E; Calarco, J R; Cardman, L S; Cavata, C; Chang, C-C; Chen, J-P; Chudakov, E; Cisbani, E; Dale, D S; de Jager, C W; De Leo, R; Deur, A; d'Hose, N; Dodge, G E; Domingo, J J; Elouadrhiri, L; Epstein, M B; Ewell, L A; Finn, J M; Fissum, K G; Fonvieille, H; Fournier, G; Frois, B; Frullani, S; Furget, C; Gao, H; Gao, J; Garibaldi, F; Gasparian, A; Gilad, S; Gilman, R; Glamazdin, A; Glashausser, C; Gomez, J; Gorbenko, V; Grenier, P; Guichon, P A M; Hansen, J O; Holmes, R; Holtrop, M; Howell, C; Huber, G M; Hyde-Wright, C E; Incerti, S; Iodice, M; Jardillier, J; Jones, M K; Kahl, W; Kato, S; Katramatou, A T; Kelly, J J; Kerhoas, S; Ketikyan, A; Khayat, M; Kino, K; Kox, S; Kramer, L H; Kumar, K S; Kumbartzki, G; Kuss, M; Leone, A; LeRose, J J; Liang, M; Lindgren, R A; Liyanage, N; Lolos, G J; Lourie, R W; Madey, R; Maeda, K; Malov, S; Manley, D M; Marchand, C; Marchand, D; Margaziotis, D J; Markowitz, P; Marroncle, J; Martino, J; McCormick, K; McIntyre, J; Mehrabyan, S; Merchez, F; Meziani, Z E; Michaels, R; Miller, G W; Mougey, J Y; Nanda, S K; Neyret, D; Offermann, E A J M; Papandreou, Z; Pasquini, B; Perdrisat, C F; Perrino, R; Petratos, G G; Platchkov, S; Pomatsalyuk, R; Prout, D L; Punjabi, V A; Pussieux, T; Quémenér, G; Ransome, R D; Ravel, O; Real, J S; Renard, F; Roblin, Y; Rowntree, D; Rutledge, G; Rutt, P M; Saha, A; Saito, T; Sarty, A J; Serdarevic, A; Smith, T; Smirnov, G; Soldi, K; Sorokin, P; Souder, P A; Suleiman, R; Templon, J A; Terasawa, T; Tieulent, R; Tomasi-Gustaffson, E; Tsubota, H; Ueno, H; Ulmer, P E; Urciuoli, G M; Vanderhaeghen, M; Van De Vyver, R; Van der Meer, R L J; Vernin, P; Vlahovic, B; Voskanyan, H; Voutier, E; Watson, J W; Weinstein, L B; Wijesooriya, K; Wilson, R; Wojtsekhowski, B B; Zainea, D G; Zhang, W-M; Zhao, J; Zhou, Z-L

    2004-09-17

    We report a virtual Compton scattering study of the proton at low c.m. energies. We have determined the structure functions P(LL)-P(TT)/epsilon and P(LT), and the electric and magnetic generalized polarizabilities (GPs) alpha(E)(Q2) and beta(M)(Q2) at momentum transfer Q(2)=0.92 and 1.76 GeV2. The electric GP shows a strong falloff with Q2, and its global behavior does not follow a simple dipole form. The magnetic GP shows a rise and then a falloff; this can be interpreted as the dominance of a long-distance diamagnetic pion cloud at low Q2, compensated at higher Q2 by a paramagnetic contribution from piN intermediate states.

  6. A Compact, Low Resource Instrument to Measure Atmospheric Methane and Carbon Dioxide From Orbit

    Science.gov (United States)

    Rafkin, Scot; Davis, Michael; Varner, Ruth; Basu, Sourish; Bruhwiler, Lori; Luspay-Kuti, Adrienn; Mandt, Kathy; Roming, Pete; Soto, Alejandro; Tapley, Mark

    2017-04-01

    Methane is the second most important radiatively active trace gas forcing anthropogenic climate change. Methane has ˜28 times more warming potential than carbon dioxide on a 100-year time horizon, and the background atmospheric concentration of methane has increased by more than 150% compared to pre-industrial levels. The increase in methane abundance is driven by a combination of direct human activity, such as fossil fuel extraction and agriculture, and natural feedback processes that respond to human-induced climate change, such as increased wetland production. Accurate accounting of the exchange between the atmosphere and the natural and anthropogenic methane reservoirs is necessary to predict how methane concentration will increase going forward, how that increase will modulate the natural methane cycle, and how effective policy decisions might be at mitigating methane-induced climate change. Monitoring and quantifying methane source intensity and spatial-temporal variability has proven challenging; there are unresolved and scientifically significant discrepancies between flux estimates based on limited surface measurements (the so-called "bottom-up" method) and the values derived from limited, remotely-sensed estimates from orbit and modeling (the so-called "top-down" method). A major source of the discrepancy between bottom-up and top-down estimates is likely a result of insufficient accuracy and resolution of space-based instrumentation. Methane releases, especially anthropogenic sources, are often at kilometer-scale (or less), whereas past remote sensing instruments have at least an order of magnitude greater footprint areas. Natural sources may be larger in areal extent, but the enhancement over background levels can be just a few percent, which demands high spectral resolution and signal-to-noise ratios from monitoring instrumentation. In response to the need for higher performance space-based methane monitoring, we have developed a novel, compact, low

  7. Comparison of V/Q SPECT and planar V/Q lung scintigraphy in diagnosing acute pulmonary embolism

    DEFF Research Database (Denmark)

    Borgwardt, Henrik Gutte; Mortensen, Jann; Jensen, Claus Verner

    2010-01-01

    Planar ventilation/perfusion (V/Q) scintigraphy is currently the standard method for the diagnosis of pulmonary embolism (PE) in most nuclear medicine centers. However, recent studies have shown a superior sensitivity and specificity when applying V/Q single photon emission computed tomography...... (SPECT) in diagnosing PE. This study evaluated the diagnostic performance of three-dimensional V/Q SPECT in comparison with planar V/Q scintigraphy....

  8. q-entropy for symbolic dynamical systems

    International Nuclear Information System (INIS)

    Zhao, Yun; Pesin, Yakov

    2015-01-01

    For symbolic dynamical systems we use the Carathéodory construction as described in (Pesin 1997 Dimension Theory in Dynamical Systems, ConTemporary Views and Applications (Chicago: University of Chicago Press)) to introduce the notions of q-topological and q-metric entropies. We describe some basic properties of these entropies and in particular, discuss relations between q-metric entropy and local metric entropy. Both q-topological and q-metric entropies are new invariants respectively under homeomorphisms and metric isomorphisms of dynamical systems. (paper)

  9. Trisomy 2q11.2-->q21.1 resulting from an unbalanced insertion in two generations.

    Science.gov (United States)

    Glass, I A; Stormer, P; Oei, P T; Hacking, E; Cotter, P D

    1998-01-01

    In this communication, we describe two cases of proximal 2q trisomy (2q11.2--> q21.1) resulting from an interchromosomal insertion. The chromosomal origin of the insertion was confirmed by fluorescence in situ hybridisation. An unbalanced karyotype, 46,XX,der(8) ,ins(8;2) (p21.3; q21.1q11.2), was found in the proband and her mother, who both have mild mental retardation, short stature, dysmorphic features, insulin dependent diabetes mellitus, and a psychotic illness. This family is a rare example of direct transmission of a partial autosomal trisomy. Images PMID:9598728

  10. The clinical presentation of attention deficit-hyperactivity disorder (ADHD) in children with 22q11.2 deletion syndrome.

    Science.gov (United States)

    Niarchou, Maria; Martin, Joanna; Thapar, Anita; Owen, Michael J; van den Bree, Marianne B M

    2015-12-01

    Although attention deficit-hyperactivity disorder (ADHD) is the most prevalent psychiatric disorder in children with 22q11.2DS, it remains unclear whether its clinical presentation is similar to that in children with idiopathic ADHD. The aim of this study is to compare the ADHD phenotype in children with and without 22q11.2DS by examining ADHD symptom scores, patterns of psychiatric comorbidity, IQ and gender distribution. Forty-four children with 22q11.2DS and ADHD (mean age = 9.6), 600 clinic children (mean age = 10.8) and 77 children with ADHD from a population cohort (mean age = 10.8) participated in the study. Psychopathology was assessed using parent-report research diagnostic instruments. There was a higher proportion of females in the 22q11.2DS ADHD sample in relation to the clinical sample (χ(2)  = 18.2, P ADHD inattentive subtype (χ(2)  = 114.76, P hyperactive-impulsive symptoms compared to the clinical group (z = 8.43, P ADHD group parents reported fewer oppositional defiant disorder/conduct disorder symptoms (z = 6.33, P disorder (χ(2)  = 4.56, P = 0.03) in relation to the clinical group. Two percent of the 22q11.2 DS ADHD sample had received ADHD treatment. The results were similar when the 22q11.2 ADHD group was compared to the population cohort ADHD group. The clinical presentation of ADHD and patterns of co-morbidity in 22q11.2DS is different from that in idiopathic ADHD. This could lead to clinical under-recognition of ADHD in this group. Examining psychopathology in 22q11.2DS can provide insights into the genetic origins of psychiatric problems with implications beyond the 22q11.2DS population. © 2015 Wiley Periodicals, Inc.

  11. Low Power 2-Bit ADC Array with Serial Output, Phase II

    Data.gov (United States)

    National Aeronautics and Space Administration — Microwave interferometers for NASA missions such as PATH employ the GeoSTAR instrument, consisting of 600 receivers. Each receiver requires I and Q ADCs...

  12. On sums of q-independent SU[sub q](2) quantum variables

    Energy Technology Data Exchange (ETDEWEB)

    Lenczewski, R. (Politechnika Wroclawska, Wroclaw (Poland). Hugo Steinhaus Center for Stochastic Methods)

    1993-05-01

    A representation-free approach to the q-analog of the quantum central limit theorem for C=SU[sub 1](2) is presented. It is shown that for certain functions [phi][epsilon]-C* one can derive a version of a quantum central limit theorem (qclt) with [radical][N] as a scaling parameter, which may be viewed as a q-analog of qclt. (orig.).

  13. Symbiotic essential amino acids provisioning in the American cockroach, Periplaneta americana (Linnaeus) under various dietary conditions.

    Science.gov (United States)

    Ayayee, Paul A; Larsen, Thomas; Sabree, Zakee

    2016-01-01

    Insect gut microbes have been shown to provide nutrients such as essential amino acids (EAAs) to their hosts. How this symbiotic nutrient provisioning tracks with the host's demand is not well understood. In this study, we investigated microbial essential amino acid (EAA) provisioning in omnivorous American cockroaches (Periplaneta americana), fed low-quality (LQD) and comparatively higher-quality dog food (DF) diets using carbon stable isotope ratios of EAAs (δ (13)CEAA). We assessed non-dietary EAA input, quantified as isotopic offsets (Δ(13)C) between cockroach (δ (13)CCockroach EAA) and dietary (δ (13)CDietary EAA) EAAs, and subsequently determined biosynthetic origins of non-dietary EAAs in cockroaches using (13)C-fingerprinting with dietary and representative bacterial and fungal δ (13)CEAA. Investigation of biosynthetic origins of de novo non-dietary EAAs indicated bacterial origins of EAA in cockroach appendage samples, and a mixture of fungal and bacterial EAA origins in gut filtrate samples for both LQD and DF-fed groups. We attribute the bacteria-derived EAAs in cockroach appendages to provisioning by the fat body residing obligate endosymbiont, Blattabacterium and gut-residing bacteria. The mixed signatures of gut filtrate samples are attributed to the presence of unassimilated dietary, as well as gut microbial (bacterial and fungal) EAAs. This study highlights the potential impacts of dietary quality on symbiotic EAA provisioning and the need for further studies investigating the interplay between host EAA demands, host dietary quality and symbiotic EAA provisioning in response to dietary sufficiency or deficiency.

  14. The use of coenzyme Q0 as a template in the development of a molecularly imprinted polymer for the selective recognition of coenzyme Q10.

    Science.gov (United States)

    Contin, Mario; Flor, Sabrina; Martinefski, Manuela; Lucangioli, Silvia; Tripodi, Valeria

    2014-01-07

    In this work, a novel molecularly imprinted polymer (MIP) for use as a solid phase extraction sorbent was developed for the determination of coenzyme Q10 (CoQ10) in liver extract. CoQ10 is an essential cofactor in mitochondrial oxidative phosphorylation and a powerful antioxidant agent found in low concentrations in biological samples. This fact and its high hydrophobicity make the analysis of CoQ10 technically challenging. Accordingly, a MIP was synthesised using coenzyme Q0 as the template, methacrylic acid as the functional monomer, acetonitrile as the porogen, ethylene glycol dimethacrylate as the crosslinker and benzoyl peroxide as the initiator. Various parameters affecting the polymer preparation and extraction efficiency were evaluated. Morphological characterisation of the MIP and its proper comparison with C18 as a sorbent in solid phase extraction were performed. The optimal conditions for the molecularly imprinted solid phase extraction (MISPE) consisted of 400 μL of sample mixed with 30 mg of MIP and 600 μL of water to reach the optimum solution loading. The loading was followed by a washing step consisting of 1 mL of a 1-propanol solution (1-propanol:water, 30:70,v/v) and elution with 1 mL of 1-propanol. After clean-up, the CoQ10 in the samples was analysed by high performance liquid chromatography. The extraction recoveries were higher than 73.7% with good precision (3.6-8.3%). The limits of detection and quantification were 2.4 and 7.5 μg g(-1), respectively, and a linear range between 7.5 and 150 μg g(-1) of tissue was achieved. The new MISPE procedure provided a successful clean-up for the determination of CoQ10 in a complex matrix. Copyright © 2013 Elsevier B.V. All rights reserved.

  15. X Q TANG

    Indian Academy of Sciences (India)

    Home; Journals; Bulletin of Materials Science. X Q TANG. Articles written in Bulletin of Materials Science. Volume 41 Issue 2 April 2018 pp 51. Effect of oxygen vacancies on Li-storage of anatase TiO 2 (001) facets: a first principles study · H CHEN Y H DING X Q TANG W ZHANG J R YIN P ZHANG Y JIANG · More Details ...

  16. Validation of the Mental Illness Sexual Stigma Questionnaire (MISS-Q in a sample of Brazilian adults in psychiatric care

    Directory of Open Access Journals (Sweden)

    Milton Wainberg

    Full Text Available ABSTRACT Objective We evaluated the psychometric properties of a new instrument “Mental Illness Sexual Stigma Questionnaire” (MISS-Q. Methods We interviewed 641 sexually active adults (ages 18-80 attending public outpatient psychiatric clinics in Rio de Janeiro about their stigma experiences. Results Nine factors were extracted through exploratory factor analysis (EFA and labeled: ‘individual discrimination by others’; ‘staff willingness to talk about sexuality’; ‘staff and family prohibitions’; ‘sexual devaluation of self’; ‘perceived attractiveness’; ‘mental illness concealment’; ‘perceived sexual role competence’; ‘withdrawal’; and ‘locus of social-sexual control’. ‘Withdrawal’ and ‘locus of social-sexual control’ showed poor psychometric properties and were excluded from further analysis. The remaining seven factors had high factorial loadings (.39 to .86, varying from sufficient to optimal reliability (Ordinal α ranged from .57 to .88, and good convergent and discriminant validity. Conclusions The resulting MISS-Q is the first instrument assessing mental illness sexual stigma with demonstrated psychometric properties. It may prove useful in reducing stigma, protecting sexual health, and promoting recovery.

  17. Invariant-mass distributions for the pp{yields}pp{eta} reaction at Q=10 MeV

    Energy Technology Data Exchange (ETDEWEB)

    Moskal, P.; Czerwinski, E.; Klaja, J.; Klaja, P.; Krzemien, W. [Jagellonian University, Institute of Physics, Cracow (Poland); Research Center Juelich, Nuclear Physics Institute, Juelich (Germany); Czyzykiewicz, R. [Jagellonian University, Institute of Physics, Cracow (Poland); University of Silesia, Institute of Physics, Katowice (Poland); Gil, D.; Jarczyk, L.; Kamys, B.; Silarski, M.; Smyrski, J.; Zdebik, J.; Zielinski, M.J. [Jagellonian University, Institute of Physics, Cracow (Poland); Grzonka, D.; Oelert, W.; Ritman, J.; Sefzick, T.; Wuestner, P. [Research Center Juelich, Nuclear Physics Institute, Juelich (Germany); Khoukaz, A.; Taeschner, A.; Zipper, W. [Westfaelische Wilhelms-Universitaet, IKP, Muenster (Germany); Siemaszko, M. [University of Silesia, Institute of Physics, Katowice (Poland); Wolke, M. [SE-751 05 Uppsala University, Department of Physics and Astronomy, Uppsala (Sweden)

    2010-02-15

    Proton-proton and proton-{eta} invariant-mass distributions and the total cross-section for the pp{yields}pp{eta} reaction have been determined near the threshold at an excess energy of Q=10 MeV. The experiment has been conducted using the COSY-11 detector setup and the cooler synchrotron COSY. The determined invariant-mass spectra reveal significant enhancements in the region of low proton-proton relative momenta, similarly as observed previously at higher excess energies of Q=15.5 MeV and Q=40 MeV. (orig.)

  18. Rosuvastatin lowers coenzyme Q10 levels, but not mitochondrial adenosine triphosphate synthesis, in children with familial hypercholesterolemia

    NARCIS (Netherlands)

    Avis, Hans J.; Hargreaves, Ian P.; Ruiter, Jos P. N.; Land, John M.; Wanders, Ronald J.; Wijburg, Frits A.

    2011-01-01

    To investigate whether statin therapy affects coenzyme Q10 (CoQ10) status in children with heterozygous familial hypercholesterolemia (FH). Samples were obtained at baseline (treatment naïve) and after dose titration with rosuvastatin, aiming for a low-density lipoprotein cholesterol level of 110

  19. Integrable Equations of the Form qt=L1(x,t,q,qx,qxx)qxxx+L2(x,t,q,qx,qxx)

    International Nuclear Information System (INIS)

    Satir, Ahmet

    2003-01-01

    Integrable equations of the form q t =L 1 (x,t,q,q x ,q xx )q xxx +L 2 (x,t,q,q x ,q xx ) are considered using linearization. A new type of integrable equations which are the generalization of the integrable equations of Fokas and Ibragimov and Shabat are given

  20. Q-balls in flat potentials

    International Nuclear Information System (INIS)

    Copeland, Edmund J.; Tsumagari, Mitsuo I.

    2009-01-01

    We study the classical and absolute stability of Q-balls in scalar field theories with flat potentials arising in both gravity-mediated and gauge-mediated models. We show that the associated Q-matter formed in gravity-mediated potentials can be stable against decay into their own free particles as long as the coupling constant of the nonrenormalizable term is small, and that all of the possible three-dimensional Q-ball configurations are classically stable against linear fluctuations. Three-dimensional gauge-mediated Q-balls can be absolutely stable in the thin-wall limit, but are completely unstable in the thick-wall limit.

  1. Planck 2015 results. IV. Low Frequency Instrument beams and window functions

    CERN Document Server

    Ade, P.A.R.; Ashdown, M.; Aumont, J.; Baccigalupi, C.; Banday, A.J.; Barreiro, R.B.; Bartolo, N.; Battaner, E.; Benabed, K.; Benoît, A.; Benoit-Lévy, A.; Bernard, J.-P.; Bersanelli, M.; Bielewicz, P.; Bock, J.J.; Bonaldi, A.; Bonavera, L.; Bond, J.R.; Borrill, J.; Bouchet, F.R.; Bucher, M.; Burigana, C.; Butler, R.C.; Calabrese, E.; Cardoso, J.-F.; Catalano, A.; Chamballu, A.; Christensen, P.R.; Colombi, S.; Colombo, L.P.L.; Crill, B.P.; Curto, A.; Cuttaia, F.; Danese, L.; Davies, R.D.; Davis, R.J.; de Bernardis, P.; de Rosa, A.; de Zotti, G.; Delabrouille, J.; Dickinson, C.; Diego, J.M.; Dole, H.; Donzelli, S.; Doré, O.; Douspis, M.; Ducout, A.; Dupac, X.; Efstathiou, G.; Elsner, F.; Enßlin, T.A.; Eriksen, H.K.; Fergusson, J.; Finelli, F.; Forni, O.; Frailis, M.; Franceschi, E.; Frejsel, A.; Galeotta, S.; Galli, S.; Ganga, K.; Giard, M.; Giraud-Héraud, Y.; Gjerløw, E.; González-Nuevo, J.; Górski, K.M.; Gratton, S.; Gregorio, A.; Gruppuso, A.; Hansen, F.K.; Hanson, D.; Harrison, D.L.; Henrot-Versillé, S.; Herranz, D.; Hildebrandt, S.R.; Hivon, E.; Hobson, M.; Holmes, W.A.; Hornstrup, A.; Hovest, W.; Huffenberger, K.M.; Hurier, G.; Jaffe, A.H.; Jaffe, T.R.; Juvela, M.; Keihänen, E.; Keskitalo, R.; Kiiveri, K.; Kisner, T.S.; Knoche, J.; Kunz, M.; Kurki-Suonio, H.; Lähteenmäki, A.; Lamarre, J.-M.; Lasenby, A.; Lattanzi, M.; Lawrence, C.R.; Leahy, J.P.; Leonardi, R.; Lesgourgues, J.; Levrier, F.; Liguori, M.; Lilje, P.B.; Linden-Vørnle, M.; Lindholm, V.; López-Caniego, M.; Lubin, P.M.; Macías-Pérez, J.F.; Maggio, G.; Maino, D.; Mandolesi, N.; Mangilli, A.; Maris, M.; Martin, P.G.; Martínez-González, E.; Masi, S.; Matarrese, S.; Mazzotta, P.; McGehee, P.; Meinhold, P.R.; Melchiorri, A.; Mendes, L.; Mennella, A.; Migliaccio, M.; Mitra, S.; Montier, L.; Morgante, G.; Mortlock, D.; Moss, A.; Munshi, D.; Murphy, J.A.; Naselsky, P.; Nati, F.; Natoli, P.; Netterfield, C.B.; Nørgaard-Nielsen, H.U.; Novikov, D.; Novikov, I.; Paci, F.; Pagano, L.; Paoletti, D.; Partridge, B.; Pasian, F.; Patanchon, G.; Pearson, T.J.; Perdereau, O.; Perotto, L.; Perrotta, F.; Pettorino, V.; Piacentini, F.; Pierpaoli, E.; Pietrobon, D.; Pointecouteau, E.; Polenta, G.; Pratt, G.W.; Prézeau, G.; Prunet, S.; Puget, J.-L.; Rachen, J.P.; Rebolo, R.; Reinecke, M.; Remazeilles, M.; Renzi, A.; Rocha, G.; Rosset, C.; Rossetti, M.; Roudier, G.; Rubiño-Martín, J.A.; Rusholme, B.; Sandri}, M.; Santos, D.; Savelainen, M.; Scott, D.; Seiffert, M.D.; Shellard, E.P.S.; Spencer, L.D.; Stolyarov, V.; Sutton, D.; Suur-Uski, A.-S.; Sygnet, J.-F.; Tauber, J.A.; Terenzi, L.; Toffolatti, L.; Tomasi, M.; Tristram, M.; Tucci, M.; Tuovinen, J.; Umana, G.; Valenziano, L.; Valiviita, J.; Van Tent, B.; Vassallo, T.; Vielva, P.; Villa, F.; Wade, L.A.; Wandelt, B.D.; Watson, R.; Wehus, I.K.; Yvon, D.; Zacchei, A.

    2016-01-01

    This paper presents the characterization of the in-flight beams, the beam window functions, and the associated uncertainties for the Planck Low Frequency Instrument (LFI). The structure of the paper is similar to that presented in the 2013 Planck release; the main differences concern the beam normalization and the delivery of the window functions to be used for polarization analysis. The in-flight assessment of the LFI main beams relies on measurements performed during observations of Jupiter. By stacking data from seven Jupiter transits, the main beam profiles are measured down to -25 dB at 30 and 44 GHz, and down to -30 dB at 70 GHz. The agreement between the simulated beams and the measured beams is confirmed to be better than 1% at each LFI frequency band (within the 20 dB contour from the peak, the rms values are: 0.1% at 30 and 70 GHz; 0.2% at 44 GHz). Simulated polarized beams are used for the computation of the effective beam window functions. The error budget for the window functions is estimated fro...

  2. q-deformations of noncompact Lie (super-) algebras: The examples of q-deformed Lorentz, Weyl, Poincare' and (super-) conformal algebras

    International Nuclear Information System (INIS)

    Dobrev, V.K.

    1992-01-01

    We review and explain a canonical procedure for the q-deformation of the real forms G of complex Lie (super-) algebras associated with (generalized) Cartan matrices. Our procedure gives different q-deformations for the non-conjugate Cartan subalgebras of G. We give several in detail the q-deformed Lorentz and conformal (super-) algebras. The q-deformed conformal algebra contains as a subalgebra a q-deformed Poincare algebra and as Hopf subalgebras two conjugate 11-generator q-deformed Weyl algebras. The q-deformed Lorentz algebra in Hopf subalgebra of both Weyl algebras. (author). 24 refs

  3. PAR-Q & YOU Questionnaire and cardiovascular history of elderly patients on dialysis engaged in physical activity

    Directory of Open Access Journals (Sweden)

    Jorge Enrique Moreno-Collazos

    2017-10-01

    Full Text Available Introduction: During the last few years, physical activity has become a therapeutic tool and a protective mechanism for the elderly; it reduces cardiovascular risk in patients undergoing different types of dialysis and receiving palliative care. Objective: The aim of this study was to establish the inclusion criteria for a therapeutic physical activity program through the use of the PAR-Q & YOU Questionnaire with elderly patients treated with different types of hemodialysis, and to relate it with cardiovascular risk factors. Methods: Pearson's chi-squared test was used to determine the possible association among variables, considering the medical history and discomfort caused by physical activity against the results of PAR-Q & YOU. Binary logistic regression was used with the variables in the chi-squared test. Conclusions: Through logistic regression, we found that cardiovascular history was 10.44 times more significant to establish the relevance of the PAR-Q & YOU as a basic assessment instrument for the inclusion in a physical activity program which is part of a physiotherapy-led renal rehabilitation.

  4. Instrumental analysis of low level of Cs-137 in marine samples by gamma spectrometry; Analise instrumental de baixos niveis de Cs-137 em amostras marinhas por espectrometria gama

    Energy Technology Data Exchange (ETDEWEB)

    Figueira, Rubens C.L.; Silva, Luiz R.N.; Figueiredo, Ana M.G.; Cunha, Ieda I.L. [Instituto de Pesquisas Energeticas e Nucleares (IPEN), Sao Paulo, SP (Brazil). Supervisao de Radioquimica

    1997-12-31

    An instrumental method for low level Cs-137 analysis in marine samples is presented. The method consists in the detector calibration, as well as, determination of detector counting efficiency, accumulative counting of both background and sample and smoothing of 661.6 keV photopeak. The methodology was applied in reference samples and in sediments samples of south Brazilian coast 11 refs., 6 figs., 4 tabs.; e-mail: figueira at net.ipen.br

  5. Chromosome 15q overgrowth syndrome: Prenatal diagnosis, molecular cytogenetic characterization, and perinatal findings in a fetus with dup(15(q26.2q26.3

    Directory of Open Access Journals (Sweden)

    Chih-Ping Chen

    2011-09-01

    Conclusion: The present case provides evidence for prenatal overgrowth, craniosynostosis, and characteristic facial dysmorphism in association with a duplication of 15q26.2→q26.3 and a duplication of the IGF1R gene. Prenatal diagnosis of fetal overgrowth should include a differential diagnosis of the chromosome 15q overgrowth syndrome.

  6. High-Q microsphere resonators for angular velocity sensing in gyroscopes

    International Nuclear Information System (INIS)

    An, Panlong; Zheng, Yongqiu; Yan, Shubin; Xue, Chenyang; Liu, Jun; Wang, Wanjun

    2015-01-01

    A resonator gyroscope based on the Sagnac effect is proposed using a core unit that is generated by water-hydrogen flame melting. The relationship between the quality factor Q and diameter D is revealed. The Q factor of the spectral lines of the microsphere cavity coupling system, which uses tapered fibers, is found to be 10 6 or more before packaging with a low refractive curable ultraviolet polymer, although it drops to approximately 10 5 after packaging. In addition, a rotating test platform is built, and the transmission spectrum and discriminator curves of a microsphere cavity with Q of 3.22×10 6 are measured using a semiconductor laser (linewidth less than 1 kHz) and a real-time proportional-integral circuit tracking and feedback technique. Equations fitting the relation between the voltage and angular rotation rate are obtained. According to the experimentally measured parameters, the sensitivity of the microsphere-coupled system can reach 0.095 ∘ /s

  7. An estimate of higher twist at small xB and low Q2 based upon a saturation model

    International Nuclear Information System (INIS)

    Bartels, J.; Peters, K.

    2000-03-01

    We investigate the influence of higher twist corrections to deep inelastic structure functions in the low-Q 2 and small-x HERA region. We review the general features of the lowest-order QCD diagrams which contribute to twist-4 at small-x, in particular the sign structure of longitudinal and transverse structure functions which offers the possibility of strong cancellations in F 2 . For a numerical analysis we perform a twist analysis of the saturation model which has been very successful both in describing the structure function and the DIS diffractive cross section at HERA. As the main conclusion, twist 4 corrections are not small in F L or F T but in F 2 = F L + F T they almost cancel. We point out that F L analysis needs a large twist-4 correction. We also indicate the region of validity of the twist expansion. (orig.)

  8. Enhancement of numeric cognition in children with low achievement in mathematic after a non-instrumental musical training.

    Science.gov (United States)

    Ribeiro, Fabiana Silva; Santos, Flávia H

    2017-03-01

    Studies suggest that musical training enhances spatial-temporal reasoning and leads to greater learning of mathematical concepts. The aim of this prospective study was to verify the efficacy of a Non-Instrumental Musical Training (NIMT) on the Numerical Cognition systems in children with low achievement in math. For this purpose, we examined, with a cluster analysis, whether children with low scores on Numerical Cognition would be grouped in the same cluster at pre and post-NIMT. Participants were primary school children divided into two groups according to their scores on an Arithmetic test. Results with a specialized battery of Numerical Cognition revealed improvements for Cluster 2 (children with low achievement in math) especially for number production capacity compared to normative data. Besides, the number of children with low scores in Numerical Cognition decreased at post-NIMT. These findings suggest that NIMT enhances Numerical Cognition and seems to be a useful tool for rehabilitation of children with low achievement in math. Copyright © 2016 Elsevier Ltd. All rights reserved.

  9. Analysis of alpha spectrum instrumental errors accounting for the low energy part of semiconductor detector response function

    International Nuclear Information System (INIS)

    Gurbich, A.F.

    1981-01-01

    A technique for processing of instrumental spectrum of charged particles permitting to take account of a low-energy part of spectrometer line shape, to improve accuracy and to estimate detection efficiency is stated on the example of 226 Ra alpha spectrum. The results obtained show that relative intensities of alpha lines within the limits of statistical errors coincide with the known values, line ''tails'' constituting to 3% of total area of the line. Taking account of ''the line tail'' results in shift of centers of peak gravity by 10-20 keV. So low-energy part of the alpha spectrometer line, which is usually not taken account during spectra processing, markedly affect the results [ru

  10. Hamm q.q./ABN AMRO: inning van stil verpande vorderingen tijdens faillissement

    NARCIS (Netherlands)

    M.L. Tuil (Mark)

    2010-01-01

    textabstractIn deze bijdrage wordt het arrest HR 30 oktober 2009, LJN BJ0861, RvdW 2009, 1271 (Hamm q.q./ABN AMRO) besproken. Aan de orde komen de wachtperiode die voor de curator geldt op grond van het arrest ING/Verdonk, de informatieverschaffing door de curator aan de pandhouder en de kosten

  11. Providing instrumental social support is more beneficial to reduce mortality risk among the elderly with low educational level in Taiwan: a 12-year follow-up national longitudinal study.

    Science.gov (United States)

    Liao, C C; Yeh, C J; Lee, S H; Liao, W C; Liao, M Y; Lee, M C

    2015-04-01

    To evaluate whether the effects of providing or receiving social support are more beneficial to reduce mortality risk among the elderly with different educational levels. In this long-term prospective cohort study, data were retrieved from the Taiwan Longitudinal Study on Aging. This study was initiated from 1996 until 2007. The complete data from 1492 males and 1177 females aged ≥67 years were retrieved. Participants received financial, instrumental, and emotional support, and they actively provided instrumental and emotional support to others and involved in social engagement. Education attainment was divided into two levels: high and low. The low education level included illiterate and elementary school. The high education level included junior high school to senior high school and above college. Cox regression analysis was used to examine the association between providing or receiving social support on mortality with different educational levels. The average age of the participants in 1996 was 73.0 (IQR=8.0) years, and the median survival following years (1996-2007) of participants was 10.3 (IQR=6.7) years. Most participants were low educational level including illiterate (39.3%) and elementary school (41.2%). Participants with high educational level tend to be younger and more male significantly. On the contrary, participants with low educational level tend to have significant more poor income, more depression, more cognition impairment, more with IADL and ADL disability than high educational level. Most participants received instrumental support from others (95.5%) and also provided emotional support to others (97.7%). Providing instrumental support can reduce 17% of mortality risk among the elderly with a low level of education after adjusting several covariates [Hazard ratio (HR) = 0.83; 95% confidence interval (CI) = 0.70-0.99; p = 0.036]. Providing instrumental social support to others confer benefits to the giver and prolong life expectancy among the

  12. Measurement of αs(Q2) from the Gross endash Llewellyn Smith Sum Rule

    International Nuclear Information System (INIS)

    Johnson, R.A.; Vakili, M.; Kim, J.H.; Arroyo, C.G.; Bazarko, A.O.; Conrad, J.; King, B.J.; Lefmann, W.C.; McNulty, C.; Mishra, S.R.; Quintas, P.Z.; Romosan, A.; Schellman, H.; Sciulli, F.J.; Seligman, W.G.; Shaevitz, M.H.; Spentzouris, P.; Stern, E.G.; Bernstein, R.H.; Lamm, M.J.; Marsh, W.; McFarland, K.S.; Yu, J.; Bolton, T.; Naples, D.; Barbaro, L. de; Harris, D.A.; Barbaro, P. de; Bodek, A.; Budd, H.; Sakumoto, W.K.; Yang, U.K.; Kinnel, T.; Smith, W.H.

    1998-01-01

    We extract a set of values for the Gross endash Llewellyn Smith sum rule at different values of 4-momentum transfer squared (Q 2 ), by combining revised CCFR neutrino data with data from other neutrino deep-inelastic scattering experiments for 1 2 2 /c 2 . A comparison with the order α 3 s theoretical predictions yields a determination of α s at the scale of the Z -boson mass of 0.114± 0.009 0.012 . This measurement provides a new and useful test of perturbative QCD at low Q 2 , because of the low uncertainties in the higher order calculations. copyright 1998 The American Physical Society

  13. Síndrome 18 q -heredado

    Directory of Open Access Journals (Sweden)

    Manuela Herrera Martínez

    1997-08-01

    Full Text Available Se presenta el hallazgo de una monosomía 18q-heredada por translocación materna (3q, 18q, en un niño de 4 años de edad con las características clínicas típicas, que presenta retraso mental y patrón dismórfico facial. Se realizó la correlación fenotipo-cariotipo, y el árbol genealógico de la familia. Se comparan los hallazgos del paciente con otros informados en la literatura médica y se enfatiza en el interés genético del estudio clínico y citogenético de los padres.It is presented the finding of an 18q-monosomy inherited by maternal translocation (3q, 18q in a 4-year-old boy with the typical clinical characteristics, that is, mental retardation and facial dysmorphia pattern. The phenotype-karyotype correlation and the pedigree were made. The patient's findings are compared with others reported in the medical literature, and the genetical interest of the clinical and cytogenetic study of the parents is emphasized.

  14. Topical treatment with coenzyme Q10-containing formulas improves skin's Q10 level and provides antioxidative effects.

    Science.gov (United States)

    Knott, Anja; Achterberg, Volker; Smuda, Christoph; Mielke, Heiko; Sperling, Gabi; Dunckelmann, Katja; Vogelsang, Alexandra; Krüger, Andrea; Schwengler, Helge; Behtash, Mojgan; Kristof, Sonja; Diekmann, Heike; Eisenberg, Tanya; Berroth, Andreas; Hildebrand, Janosch; Siegner, Ralf; Winnefeld, Marc; Teuber, Frank; Fey, Sven; Möbius, Janne; Retzer, Dana; Burkhardt, Thorsten; Lüttke, Juliane; Blatt, Thomas

    2015-01-01

    Ubiquinone (coenzyme Q10, Q10) represents an endogenously synthesized lipid-soluble antioxidant which is crucial for cellular energy production but is diminished with age and under the influence of external stress factors in human skin. Here, it is shown that topical Q10 treatment is beneficial with regard to effective Q10 replenishment, augmentation of cellular energy metabolism, and antioxidant effects. Application of Q10-containing formulas significantly increased the levels of this quinone on the skin surface. In the deeper layers of the epidermis the ubiquinone level was significantly augmented indicating effective supplementation. Concurrent elevation of ubiquinol levels suggested metabolic transformation of ubiquinone resulting from increased energy metabolism. Incubation of cultured human keratinocytes with Q10 concentrations equivalent to treated skin showed a significant augmentation of energy metabolism. Moreover, the results demonstrated that stressed skin benefits from the topical Q10 treatment by reduction of free radicals and an increase in antioxidant capacity. © 2015 International Union of Biochemistry and Molecular Biology.

  15. A Novel Low-Cost Instrumentation System for Measuring the Water Content and Apparent Electrical Conductivity of Soils

    Directory of Open Access Journals (Sweden)

    Alan Kardek Rêgo Segundo

    2015-10-01

    Full Text Available The scarcity of drinking water affects various regions of the planet. Although climate change is responsible for the water availability, humanity plays an important role in preserving this precious natural resource. In case of negligence, the likely trend is to increase the demand and the depletion of water resources due to the increasing world population. This paper addresses the development, design and construction of a low cost system for measuring soil volumetric water content (θ, electrical conductivity (σ and temperature (T, in order to optimize the use of water, energy and fertilizer in food production. Different from the existing measurement instruments commonly deployed in these applications, the proposed system uses an auto-balancing bridge circuit as measurement method. The proposed models to estimate θ and σ and correct them in function of T are compared to the ones reported in literature. The final prototype corresponds to a simple circuit connected to a pair of electrode probes, and presents high accuracy, high signal to noise ratio, fast response, and immunity to stray capacitance. The instrument calibration is based on salt solutions with known dielectric constant and electrical conductivity as reference. Experiments measuring clay and sandy soils demonstrate the satisfactory performance of the instrument.

  16. A Novel Low-Cost Instrumentation System for Measuring the Water Content and Apparent Electrical Conductivity of Soils.

    Science.gov (United States)

    Rêgo Segundo, Alan Kardek; Martins, José Helvecio; Monteiro, Paulo Marcos de Barros; de Oliveira, Rubens Alves; Freitas, Gustavo Medeiros

    2015-10-05

    The scarcity of drinking water affects various regions of the planet. Although climate change is responsible for the water availability, humanity plays an important role in preserving this precious natural resource. In case of negligence, the likely trend is to increase the demand and the depletion of water resources due to the increasing world population. This paper addresses the development, design and construction of a low cost system for measuring soil volumetric water content (θ), electrical conductivity (σ) and temperature (T), in order to optimize the use of water, energy and fertilizer in food production. Different from the existing measurement instruments commonly deployed in these applications, the proposed system uses an auto-balancing bridge circuit as measurement method. The proposed models to estimate θ and σ and correct them in function of T are compared to the ones reported in literature. The final prototype corresponds to a simple circuit connected to a pair of electrode probes, and presents high accuracy, high signal to noise ratio, fast response, and immunity to stray capacitance. The instrument calibration is based on salt solutions with known dielectric constant and electrical conductivity as reference. Experiments measuring clay and sandy soils demonstrate the satisfactory performance of the instrument.

  17. A method for quantitative analysis of standard and high-throughput qPCR expression data based on input sample quantity.

    Directory of Open Access Journals (Sweden)

    Mateusz G Adamski

    Full Text Available Over the past decade rapid advances have occurred in the understanding of RNA expression and its regulation. Quantitative polymerase chain reactions (qPCR have become the gold standard for quantifying gene expression. Microfluidic next generation, high throughput qPCR now permits the detection of transcript copy number in thousands of reactions simultaneously, dramatically increasing the sensitivity over standard qPCR. Here we present a gene expression analysis method applicable to both standard polymerase chain reactions (qPCR and high throughput qPCR. This technique is adjusted to the input sample quantity (e.g., the number of cells and is independent of control gene expression. It is efficiency-corrected and with the use of a universal reference sample (commercial complementary DNA (cDNA permits the normalization of results between different batches and between different instruments--regardless of potential differences in transcript amplification efficiency. Modifications of the input quantity method include (1 the achievement of absolute quantification and (2 a non-efficiency corrected analysis. When compared to other commonly used algorithms the input quantity method proved to be valid. This method is of particular value for clinical studies of whole blood and circulating leukocytes where cell counts are readily available.

  18. Biochemical Assessment of Coenzyme Q10 Deficiency

    Directory of Open Access Journals (Sweden)

    Juan Carlos Rodríguez-Aguilera

    2017-03-01

    Full Text Available Coenzyme Q10 (CoQ10 deficiency syndrome includes clinically heterogeneous mitochondrial diseases that show a variety of severe and debilitating symptoms. A multiprotein complex encoded by nuclear genes carries out CoQ10 biosynthesis. Mutations in any of these genes are responsible for the primary CoQ10 deficiency, but there are also different conditions that induce secondary CoQ10 deficiency including mitochondrial DNA (mtDNA depletion and mutations in genes involved in the fatty acid β-oxidation pathway. The diagnosis of CoQ10 deficiencies is determined by the decrease of its content in skeletal muscle and/or dermal skin fibroblasts. Dietary CoQ10 supplementation is the only available treatment for these deficiencies that require a rapid and distinct diagnosis. Here we review methods for determining CoQ10 content by HPLC separation and identification using alternative approaches including electrochemical detection and mass spectrometry. Also, we review procedures to determine the CoQ10 biosynthesis rate using labeled precursors.

  19. Cost-effectiveness of decompression according to Gill versus instrumented spondylodesis in the treatment of sciatica due to low grade spondylolytic spondylolisthesis: A prospective randomised controlled trial [NTR1300

    NARCIS (Netherlands)

    M.P. Arts (Mark); M.J.T. Verstegen (Marco); R. Brand (René); B.W. Koes (Bart); M.E. van den Akker-van Marle (Elske); W.C. Peul (Wilco)

    2008-01-01

    textabstractBackground. Nerve root decompression with instrumented spondylodesis is the most frequently performed surgical procedure in the treatment of patients with symptomatic low-grade spondylolytic spondylolisthesis. Nerve root decompression without instrumented fusion, i.e. Gill's procedure,

  20. Artificial intelligence techniques coupled with seasonality measures for hydrological regionalization of Q90 under Brazilian conditions

    Science.gov (United States)

    Beskow, Samuel; de Mello, Carlos Rogério; Vargas, Marcelle M.; Corrêa, Leonardo de L.; Caldeira, Tamara L.; Durães, Matheus F.; de Aguiar, Marilton S.

    2016-10-01

    Information on stream flows is essential for water resources management. The stream flow that is equaled or exceeded 90% of the time (Q90) is one the most used low stream flow indicators in many countries, and its determination is made from the frequency analysis of stream flows considering a historical series. However, stream flow gauging network is generally not spatially sufficient to meet the necessary demands of technicians, thus the most plausible alternative is the use of hydrological regionalization. The objective of this study was to couple the artificial intelligence techniques (AI) K-means, Partitioning Around Medoids (PAM), K-harmonic means (KHM), Fuzzy C-means (FCM) and Genetic K-means (GKA), with measures of low stream flow seasonality, for verification of its potential to delineate hydrologically homogeneous regions for the regionalization of Q90. For the performance analysis of the proposed methodology, location attributes from 108 watersheds situated in southern Brazil, and attributes associated with their seasonality of low stream flows were considered in this study. It was concluded that: (i) AI techniques have the potential to delineate hydrologically homogeneous regions in the context of Q90 in the study region, especially the FCM method based on fuzzy logic, and GKA, based on genetic algorithms; (ii) the attributes related to seasonality of low stream flows added important information that increased the accuracy of the grouping; and (iii) the adjusted mathematical models have excellent performance and can be used to estimate Q90 in locations lacking monitoring.

  1. All-fibre Q-switching YDFL operation with bismuth-doped fibre as saturable absorber

    Science.gov (United States)

    Muhammad, A. R.; Haris, H.; Arof, H.; Tan, S. J.; Ahmad, M. T.; Harun, S. W.

    2018-05-01

    We demonstrate the generation of a passively Q-switched ytterbium-doped fibre laser (YDFL) using a bismuth-doped fibre (BDF) as a solid-state fibre saturable absorber (FSA) in a ring cavity. The BDF used has a wide and low absorption band of 5 dB/m at the 1.0 μm region due to the ion transition of ? that occurs around the region. When introduced into a YDFL laser cavity, a stable Q-switched pulse operation was observed and the pulse repetition rate was proportional to the input pump power. It was limited to 72.99 kHz by the maximum power that the laser diode could supply. Meanwhile, the pulse width decreased from 12.22 to 4.85 μs as the pump power was increased from 215.6 to 475.6 mW. The finding suggests that BDF could be used as a potential SA for the development of robust, compact, efficient and low cost Q-switched fibre lasers operating at 1 micron region.

  2. Coenzyme Q supplementation in pulmonary arterial hypertension

    Directory of Open Access Journals (Sweden)

    Jacqueline Sharp

    2014-01-01

    Full Text Available Mitochondrial dysfunction is a fundamental abnormality in the vascular endothelium and smooth muscle of patients with pulmonary arterial hypertension (PAH. Because coenzyme Q (CoQ is essential for mitochondrial function and efficient oxygen utilization as the electron carrier in the inner mitochondrial membrane, we hypothesized that CoQ would improve mitochondrial function and benefit PAH patients. To test this, oxidized and reduced levels of CoQ, cardiac function by echocardiogram, mitochondrial functions of heme synthesis and cellular metabolism were evaluated in PAH patients (N=8 in comparison to healthy controls (N=7, at baseline and after 12 weeks oral CoQ supplementation. CoQ levels were similar among PAH and control individuals, and increased in all subjects with CoQ supplementation. PAH patients had higher CoQ levels than controls with supplementation, and a tendency to a higher reduced-to-oxidized CoQ ratio. Cardiac parameters improved with CoQ supplementation, although 6-minute walk distances and BNP levels did not significantly change. Consistent with improved mitochondrial synthetic function, hemoglobin increased and red cell distribution width (RDW decreased in PAH patients with CoQ, while hemoglobin declined slightly and RDW did not change in healthy controls. In contrast, metabolic and redox parameters, including lactate, pyruvate and reduced or oxidized gluthathione, did not change in PAH patients with CoQ. In summary, CoQ improved hemoglobin and red cell maturation in PAH, but longer studies and/or higher doses with a randomized placebo-controlled controlled design are necessary to evaluate the clinical benefit of this simple nutritional supplement.

  3. Impact of Chemical Analogs of 4-Hydroxybenzoic Acid on Coenzyme Q Biosynthesis: From Inhibition to Bypass of Coenzyme Q Deficiency

    Directory of Open Access Journals (Sweden)

    Fabien Pierrel

    2017-06-01

    Full Text Available Coenzyme Q is a lipid that participates to important physiological functions. Coenzyme Q is synthesized in multiple steps from the precursor 4-hydroxybenzoic acid. Mutations in enzymes that participate to coenzyme Q biosynthesis result in primary coenzyme Q deficiency, a type of mitochondrial disease. Coenzyme Q10 supplementation of patients is the classical treatment but it shows limited efficacy in some cases. The molecular understanding of the coenzyme Q biosynthetic pathway allowed the design of experiments to bypass deficient biosynthetic steps with analogs of 4-hydroxybenzoic acid. These molecules provide the defective chemical group and can reactivate endogenous coenzyme Q biosynthesis as demonstrated recently in yeast, mammalian cell cultures, and mouse models of primary coenzyme Q deficiency. This mini review presents how the chemical properties of various analogs of 4-hydroxybenzoic acid dictate the effect of the molecules on CoQ biosynthesis and how the reactivation of endogenous coenzyme Q biosynthesis may achieve better results than exogenous CoQ10 supplementation.

  4. q-Extension of Mehta's eigenvectors of the finite Fourier transform for q, a root of unity

    NARCIS (Netherlands)

    Atakishiyeva, M.K.; Atakishiyev, N.M.; Koornwinder, T.H.

    2009-01-01

    It is shown that the continuous q-Hermite polynomials for q, a root of unity, have simple transformation properties with respect to the classical Fourier transform. This result is then used to construct q-extended eigenvectors of the finite Fourier transform in terms of these polynomials.

  5. Constacyclic codes over the ring F_q+v{F}_q+v2F_q and their applications of constructing new non-binary quantum codes

    Science.gov (United States)

    Ma, Fanghui; Gao, Jian; Fu, Fang-Wei

    2018-06-01

    Let R={F}_q+v{F}_q+v2{F}_q be a finite non-chain ring, where q is an odd prime power and v^3=v. In this paper, we propose two methods of constructing quantum codes from (α +β v+γ v2)-constacyclic codes over R. The first one is obtained via the Gray map and the Calderbank-Shor-Steane construction from Euclidean dual-containing (α +β v+γ v2)-constacyclic codes over R. The second one is obtained via the Gray map and the Hermitian construction from Hermitian dual-containing (α +β v+γ v2)-constacyclic codes over R. As an application, some new non-binary quantum codes are obtained.

  6. q-bar q condensate for light quarks beyond the chiral limit

    International Nuclear Information System (INIS)

    Williams, R.; Fischer, C.S.; Pennington, M.R.

    2007-01-01

    We determine the q-bar q condensate for quark masses from zero up to that of the strange quark within a phenomenologically successful modelling of continuum QCD by solving the quark Schwinger-Dyson equation. The existence of multiple solutions to this equation is the key to an accurate and reliable extraction of this condensate using the operator product expansion. We explain why alternative definitions fail to give the physical condensate

  7. Two new ternary chalcogenides Ba{sub 2}ZnQ{sub 3} (Q = Se, Te) with chains of ZnQ{sub 4} tetrahedra. Syntheses, crystal structure, and optical and electronic properties

    Energy Technology Data Exchange (ETDEWEB)

    Prakash, Jai; Beard, Jessica; Malliakas, Christos D.; Ibers, James A. [Northwestern Univ., Evanston, IL (United States). Dept. of Chemistry; Mesbah, Adel [Northwestern Univ., Evanston, IL (United States). Dept. of Chemistry; ICSM, UMR 5257 CEA/CNRS/UM2/ENSCM, Bagnols-sur-Ceze (France); Rocca, Dario; Lebegue, Sebastien [Univ. de Lorraine, Vandoeuvre-les-Nancy (France). Lab. de Cristallographie, Resonance Magnetique et Modelisations (CRM2, UMR CNRS 7036)

    2016-08-01

    Single crystals of Ba{sub 2}ZnQ{sub 3} (Q = Se, Te) were obtained by solid-state reactions at 1173 K. These isostructural compounds crystallize in the K{sub 2}AgI{sub 3} structure type. The Zn atoms in this structure are coordinated to four Q atoms (2 Q1, 1 Q2, 1 Q3) and these form a distorted tetrahedron around each Zn atom. Each ZnQ{sub 4} tetrahedron shares two corners with neighboring ZnQ{sub 4} tetrahedra resulting in the formation of infinite chains of [ZnQ{sub 4}{sup 4-}] units. The absorption spectrum of a single crystal of Ba{sub 2}ZnTe{sub 3} shows an absorption edge at 2.10(2) eV, consistent with the dark-red color of the crystals. From DFT calculations Ba{sub 2}ZnSe{sub 3} and Ba{sub 2}ZnTe{sub 3} are found to be semiconductors with electronic band gaps of 2.6 and 1.9 eV, respectively.

  8. Angelman syndrome associated with an inversion of chromosome 15q11.2q24.3

    Energy Technology Data Exchange (ETDEWEB)

    Greger, V.; Knoll, J.H.M.; Wagstaff, J.; Lalande, M. [and others

    1997-03-01

    Angelman syndrome (AS) most frequently results from large ({ge}5 Mb) de novo deletions of chromosome 15q11-q13. The deletions are exclusively of maternal origin, and a few cases of paternal uniparental disomy of chromosome 15 have been reported. The latter finding indicates that AS is caused by the absence of a maternal contribution to the imprinted 15q11-q13 region. Failure to inherit a paternal 15q11-q13 contribution results in the clinically distinct disorder of Prader-Willi syndrome. Cases of AS resulting from translocations or pericentric inversions have been observed to be associated with deletions, and there have been no confirmed reports of balanced rearrangements in AS. We report the first such case involving a paracentric inversion with a breakpoint located {approximately}25 kb proximal to the reference marker D15S10. This inversion has been inherited from a phenotypically normal mother. No deletion is evident by molecular analysis in this case, by use of cloned fragments mapped to within {approximately}1 kb of the inversion breakpoint. Several hypotheses are discussed to explain the relationship between the inversion and the AS phenotype. 47 refs., 3 figs.

  9. a Circleless "2D/3D Total STATION": a Low Cost Instrument for Surveying, Recording Point Clouds, Documentation, Image Acquisition and Visualisation

    Science.gov (United States)

    Scherer, M.

    2013-07-01

    Hardware and software of the universally applicable instrument - referred to as a 2D/3D total station - are described here, as well as its practical use. At its core it consists of a 3D camera - often also called a ToF camera, a pmd camera or a RIM-camera - combined with a common industrial 2D camera. The cameras are rigidly coupled with their optical axes in parallel. A new type of instrument was created mounting this 2D/3D system on a tripod in a specific way. Because of it sharing certain characteristics with a total station and a tacheometer, respectively, the new device was called a 2D/3D total station. It may effectively replace a common total station or a laser scanner in some respects. After a brief overview of the prototype's features this paper then focuses on the methodological characteristics for practical application. Its usability as a universally applicable stand-alone instrument is demonstrated for surveying, recording RGB-coloured point clouds as well as delivering images for documentation and visualisation. Because of its limited range (10m without reflector and 150 m to reflector prisms) and low range accuracy (ca. 2 cm to 3 cm) compared to present-day total stations and laser scanners, the practical usage of the 2D/3D total station is currently limited to acquisition of accidents, forensic purpuses, speleology or facility management, as well as architectural recordings with low requirements regarding accuracy. However, the author is convinced that in the near future advancements in 3D camera technology will allow this type of comparatively low cost instrument to replace the total station as well as the laser scanner in an increasing number of areas.

  10. The Thirty Gigahertz Instrument Receiver for the QUIJOTE Experiment: Preliminary Polarization Measurements and Systematic-Error Analysis

    Directory of Open Access Journals (Sweden)

    Francisco J. Casas

    2015-08-01

    Full Text Available This paper presents preliminary polarization measurements and systematic-error characterization of the Thirty Gigahertz Instrument receiver developed for the QUIJOTE experiment. The instrument has been designed to measure the polarization of Cosmic Microwave Background radiation from the sky, obtaining the Q, U, and I Stokes parameters of the incoming signal simultaneously. Two kinds of linearly polarized input signals have been used as excitations in the polarimeter measurement tests in the laboratory; these show consistent results in terms of the Stokes parameters obtained. A measurement-based systematic-error characterization technique has been used in order to determine the possible sources of instrumental errors and to assist in the polarimeter calibration process.

  11. The clinical presentation of attention deficit‐hyperactivity disorder (ADHD) in children with 22q11.2 deletion syndrome

    Science.gov (United States)

    Martin, Joanna; Thapar, Anita; Owen, Michael J.

    2015-01-01

    Background: Although attention deficit‐hyperactivity disorder (ADHD) is the most prevalent psychiatric disorder in children with 22q11.2DS, it remains unclear whether its clinical presentation is similar to that in children with idiopathic ADHD. The aim of this study is to compare the ADHD phenotype in children with and without 22q11.2DS by examining ADHD symptom scores, patterns of psychiatric comorbidity, IQ and gender distribution. Methods: Forty‐four children with 22q11.2DS and ADHD (mean age = 9.6), 600 clinic children (mean age = 10.8) and 77 children with ADHD from a population cohort (mean age = 10.8) participated in the study. Psychopathology was assessed using parent‐report research diagnostic instruments. Results: There was a higher proportion of females in the 22q11.2DS ADHD sample in relation to the clinical sample (χ2 = 18.2, P ADHD inattentive subtype (χ2 = 114.76, P ADHD group parents reported fewer oppositional defiant disorder/conduct disorder symptoms (z = 6.33, P ADHD sample had received ADHD treatment. The results were similar when the 22q11.2 ADHD group was compared to the population cohort ADHD group. Conclusions: The clinical presentation of ADHD and patterns of co‐morbidity in 22q11.2DS is different from that in idiopathic ADHD. This could lead to clinical under‐recognition of ADHD in this group. Examining psychopathology in 22q11.2DS can provide insights into the genetic origins of psychiatric problems with implications beyond the 22q11.2DS population. © 2015 The Authors. American Journal of Medical Genetics Part B: Neuropsychiatric Genetics Published by Wiley Periodicals, Inc. PMID:26400629

  12. NEUROD2 and NEUROD3 genes map to human chromosomes 17q12 and 5q23-q31 and mouse chromosomes 11 and 13, respectively

    Energy Technology Data Exchange (ETDEWEB)

    Tamimi, R.M.; Montgomery-Dyer, K.; Tapscott, S.J. [Fred Hutchinson Cancer Research Center, Seattle, WA (United States)] [and others

    1997-03-01

    NEUROD2 and NEUROD3 are transcription factors involved in neurogenesis that are related to the basic helix-loop-helix protein NEUROD. NEUROD2 maps to human chromosome 17q12 and mouse chromosome 11. NEUROD3 maps to human chromosome 5q23-q31 and mouse chromosome 13. 16 refs., 2 figs.

  13. Modeling qRT-PCR dynamics with application to cancer biomarker quantification.

    Science.gov (United States)

    Chervoneva, Inna; Freydin, Boris; Hyslop, Terry; Waldman, Scott A

    2017-01-01

    Quantitative reverse transcription polymerase chain reaction (qRT-PCR) is widely used for molecular diagnostics and evaluating prognosis in cancer. The utility of mRNA expression biomarkers relies heavily on the accuracy and precision of quantification, which is still challenging for low abundance transcripts. The critical step for quantification is accurate estimation of efficiency needed for computing a relative qRT-PCR expression. We propose a new approach to estimating qRT-PCR efficiency based on modeling dynamics of polymerase chain reaction amplification. In contrast, only models for fluorescence intensity as a function of polymerase chain reaction cycle have been used so far for quantification. The dynamics of qRT-PCR efficiency is modeled using an ordinary differential equation model, and the fitted ordinary differential equation model is used to obtain effective polymerase chain reaction efficiency estimates needed for efficiency-adjusted quantification. The proposed new qRT-PCR efficiency estimates were used to quantify GUCY2C (Guanylate Cyclase 2C) mRNA expression in the blood of colorectal cancer patients. Time to recurrence and GUCY2C expression ratios were analyzed in a joint model for survival and longitudinal outcomes. The joint model with GUCY2C quantified using the proposed polymerase chain reaction efficiency estimates provided clinically meaningful results for association between time to recurrence and longitudinal trends in GUCY2C expression.

  14. 氨基酸分析仪和HPLC测定食品中牛磺酸的研究比较%Research and Comparison of the Determination of Taurine in Food by Amino Acid Analyzer and HPLC

    Institute of Scientific and Technical Information of China (English)

    孙洁

    2012-01-01

    分别采用不同的仪器及方法:氨基酸分析仪茚三酮柱后衍生和高效液相色谱丹磺酰氯柱前衍生,建立对食品中牛磺酸测定的方法,比较了两种方法的检出限、定量限以及回收率等,结果表明两种仪器方法各有优点,适应在不同情况下对食品中牛磺酸进行测定。%Use different instruments and methods as amino acid analyzer ninhydrin post-column derivatization and HPLC dansyl chloride pre-column derivatization,to establish the method of determing taurine.By the comparison of LOD,LQD,recovery,etc.,the results show?that??two methods have their own advantages.They can assay?the taurine in?food?in different cases.

  15. Interstitial deletion of 5q33.3q35.1 in a boy with severe mental retardation

    OpenAIRE

    Lee, Jin Hwan; Kim, Hyo Jeong; Yoon, Jung Min; Cheon, Eun Jung; Lim, Jae Woo; Ko, Kyong Og; Lee, Gyung Min

    2016-01-01

    Constitutional interstitial deletions of the long arm of chromosome 5 (5q) are quite rare, and the corresponding phenotype is not yet clearly delineated. Severe mental retardation has been described in most patients who present 5q deletions. Specifically, the interstitial deletion of chromosome 5q33.3q35.1, an extremely rare chromosomal aberration, is characterized by mental retardation, developmental delay, and facial dysmorphism. Although the severity of mental retardation varies across cas...

  16. On q-power cycles in cubic graphs

    DEFF Research Database (Denmark)

    Bensmail, Julien

    2017-01-01

    In the context of a conjecture of Erdos and Gyárfás, we consider, for any q ≥ 2, the existence of q-power cycles (i.e. with length a power of q) in cubic graphs. We exhibit constructions showing that, for every q ≥ 3, there exist arbitrarily large cubic graphs with no q-power cycles. Concerning...... the remaining case q = 2 (which corresponds to the conjecture of Erdos and Gyárfás), we show that there exist arbitrarily large cubic graphs whose only 2-power cycles have length 4 only, or 8 only....

  17. Remote Monitoring of Instrumentation in Sealed Compartments

    International Nuclear Information System (INIS)

    Landron, Clinton; Moser, John C.

    1999-01-01

    The Instrumentation and Telemetry Departments at Sandia National Laboratories have been exploring the instrumentation of sealed canisters where the flight application will not tolerate either the presence of a chemical power source or penetration by power supply wires. This paper will describe the application of a low power micro-controller based instrumentation system that uses magnetic coupling for both power and data to support a flight application

  18. Instrumentation, computer software and experimental techniques used in low-frequency internal friction studies at WNRE

    International Nuclear Information System (INIS)

    Sprugmann, K.W.; Ritchie, I.G.

    1980-04-01

    A detailed and comprehensive account of the equipment, computer programs and experimental methods developed at the Whiteshell Nuclear Research Estalbishment for the study of low-frequency internal friction is presented. Part 1 describes the mechanical apparatus, electronic instrumentation and computer software, while Part II describes in detail the laboratory techniques and various types of experiments performed together with data reduction and analysis. Experimental procedures for the study of internal friction as a function of temperature, strain amplitude or time are described. Computer control of these experiments using the free-decay technique is outlined. In addition, a pendulum constant-amplitude drive system is described. (auth)

  19. Treatment of CoQ(10 deficient fibroblasts with ubiquinone, CoQ analogs, and vitamin C: time- and compound-dependent effects.

    Directory of Open Access Journals (Sweden)

    Luis C López

    2010-07-01

    Full Text Available Coenzyme Q(10 (CoQ(10 and its analogs are used therapeutically by virtue of their functions as electron carriers, antioxidant compounds, or both. However, published studies suggest that different ubiquinone analogs may produce divergent effects on oxidative phosphorylation and oxidative stress.To test these concepts, we have evaluated the effects of CoQ(10, coenzyme Q(2 (CoQ(2, idebenone, and vitamin C on bioenergetics and oxidative stress in human skin fibroblasts with primary CoQ(10 deficiency. A final concentration of 5 microM of each compound was chosen to approximate the plasma concentration of CoQ(10 of patients treated with oral ubiquinone. CoQ(10 supplementation for one week but not for 24 hours doubled ATP levels and ATP/ADP ratio in CoQ(10 deficient fibroblasts therein normalizing the bioenergetics status of the cells. Other compounds did not affect cellular bioenergetics. In COQ2 mutant fibroblasts, increased superoxide anion production and oxidative stress-induced cell death were normalized by all supplements.THESE RESULTS INDICATE THAT: 1 pharmacokinetics of CoQ(10 in reaching the mitochondrial respiratory chain is delayed; 2 short-tail ubiquinone analogs cannot replace CoQ(10 in the mitochondrial respiratory chain under conditions of CoQ(10 deficiency; and 3 oxidative stress and cell death can be counteracted by administration of lipophilic or hydrophilic antioxidants. The results of our in vitro experiments suggest that primary CoQ(10 deficiencies should be treated with CoQ(10 supplementation but not with short-tail ubiquinone analogs, such as idebenone or CoQ(2. Complementary administration of antioxidants with high bioavailability should be considered if oxidative stress is present.

  20. Genetics Home Reference: distal 18q deletion syndrome

    Science.gov (United States)

    ... 18q deletion syndrome chromosome 18q monosomy chromosome 18q- syndrome De Grouchy syndrome del(18q) syndrome monosomy 18q Related Information How ... MS, Tienari PJ, Wirtavuori KO, Valanne LK. 18q-syndrome: brain MRI shows poor differentiation of gray and white matter on ... RL, Hale DE, Rose SR, Leach RJ, Cody JD. The spectrum ...